guide_name number orf_type target position strand sequence mut1_C>G mut1_C>T mut2_C>G mut2_C>T stan_name name length mut_1_effect_bin mut_1_effect mut_1_proximity mut_2_effect_bin mut_2_effect mut_2_proximity z_score_meanSE uniprot_ID mut1_C>G_envision mut1_C>T_envision mut2_C>G_envision mut2_C>T_envision mut1_C>G_SIFT mut1_C>T_SIFT mut2_C>G_SIFT mut2_C>T_SIFT mut1_C>G_ddg_exp mut1_C>T_ddg_exp mut2_C>G_ddg_exp mut2_C>T_ddg_exp mut1_C>G_ddg_model mut1_C>T_ddg_model mut2_C>G_ddg_model mut2_C>T_ddg_model mut1_C>G_ddg_inter mut1_C>T_ddg_inter mut2_C>G_ddg_inter mut2_C>T_ddg_inter grna_binding %GC orf_strand over_threshold 0 chrI_55603r 1 high_effect YAL047C 1232 + GGACAGCTACATCAATGACT D|412|E silent|GAC>GAT|D|412 S|413|R silent|AGC>AGT|S|413 SPC72 Spindle Pole Component 622.0 0 0 0 0 -0.7588021324418249 P39723 1.0 0.3609844446182251 45.56282838650203 45.0 0.0 no 1 chrI_55964 3 high_effect YAL047C 874 - AATCTCTAATTGAGTGTCTA E|297|D silent|GAG>GAA|E|297 E|297|Q E|297|K SPC72 Spindle Pole Component 622.0 0 0 0 0 -0.03536652172867144 P39723 0.0 0.0 0.0 39.776378809185466 30.0 0.0 no 2 chrI_56041 6 high_effect YAL047C 797 - TTACATTTTCTGTATCAATG V|272|L V|272|I SPC72 Spindle Pole Component 622.0 0 0 0 0 0.5085976236017596 P39723 0.18256093561649325 0.30061811208724976 36.81687523152532 25.0 0.0 no 3 chrI_56071 7 high_effect YAL047C 767 - TGTCATGAATTTCGTCATTC D|262|H D|262|N SPC72 Spindle Pole Component 622.0 0 0 0 0 0.16276537663918098 P39723 42.444084673666175 35.0 0.0 no 4 chrI_56300 11 high_effect YAL047C 538 - CAGCTCTAAAGTTTCCTCCA E|185|D silent|GAG>GAA|E|185 E|185|Q E|185|K SPC72 Spindle Pole Component 622.0 0 0 0 0 -0.014450405304661297 P39723 0.4956592619419098 0.4632943570613861 0.6069009900093079 51.26836814676972 45.0 0.0 no 5 chrI_56299 12 high_effect YAL047C 539 - TCAGCTCTAAAGTTTCCTCC silent|CTG>CTC|L|186 silent|CTG>CTA|L|186 E|185|D silent|GAG>GAA|E|185 SPC72 Spindle Pole Component 622.0 0 0 0 0 -0.1890929375189476 P39723 0.4956592619419098 51.13230876018185 45.0 0.0 no 6 chrI_56329 13 high_effect YAL047C 509 - TCTCTTCTTTATCAAGAAGA E|176|Q E|176|K E|176|D silent|GAG>GAA|E|176 SPC72 Spindle Pole Component 622.0 0 0 0 0 0.9318596723505136 P39723 0.17505468428134918 0.3397166728973389 0.16147851943969727 39.411463678384735 30.0 0.0 no 7 chrI_56563r 17 high_effect YAL047C 272 + AGACGGCAATGCACCATCGC D|92|E silent|GAC>GAT|D|92 silent|GGC>GGG|G|93 silent|GGC>GGT|G|93 SPC72 Spindle Pole Component 622.0 0 0 0 0 -0.8015773013919063 P39723 0.5990722179412842 53.59060977447307 60.0 0.0 no 8 chrI_56802r 25 high_effect YAL047C 33 + CTTCGCAATAATGACAACAC R|13|G R|13|C silent|CGC>CGG|R|13 silent|CGC>CGT|R|13 SPC72 Spindle Pole Component 622.0 0 0 0 0 0.1822632907778441 P39723 0.050341147929430015 0.007041571196168661 39.114411203792145 40.0 0.0 no 9 chrI_59370 30 essential YAL043C 1663 - GGCATCTCCTGAGATTTCTT A|561|P A|561|T D|560|H D|560|N PTA1 Pre-Trna Accumulation 785.0 0 0 0 0 -0.6892096603349838 Q01329 0.9573720097541808 0.9523990154266356 0.9486550092697144 0.956179976463318 0.20779794454574585 0.4186466634273529 0.09343738853931427 0.3821389377117157 52.5742621336841 45.0 0.0 no 10 chrI_59443 35 essential YAL043C 1590 - TCCTCTGGTTCCTCCGCTAG E|536|D silent|GAG>GAA|E|536 E|537|Q E|537|K PTA1 Pre-Trna Accumulation 785.0 0 0 0 0 -4.4969226944919765 Q01329 0.94931298494339 0.956179976463318 0.9475290179252625 0.5941016674041748 0.4834935069084168 0.6944926381111145 61.99725630779312 60.0 0.0 yes 11 chrI_59641r 40 essential YAL043C 1389 + GACAGCACGAAACTGATCAC D|464|E silent|GAC>GAT|D|464 S|465|R silent|AGC>AGT|S|465 PTA1 Pre-Trna Accumulation 785.0 0 0 0 0 0.7158472155241475 Q01329 0.9532920122146606 0.9417110085487366 0.028203882277011868 0.00931382179260254 43.361051402433084 50.0 0.0 no 12 chrI_59678r 42 essential YAL043C 1352 + ACTTATCAAGCTGTCCACAG L|452|V L|452|F I|453|M silent|ATC>ATT|I|453 PTA1 Pre-Trna Accumulation 785.0 0 0 0 0 0.287037568593188 Q01329 0.9512209892272948 0.9587849974632264 0.9598389863967896 0.04421529173851013 0.03835012763738632 0.03707019612193108 48.073771232071685 45.0 0.0 no 13 chrI_59726r 45 essential YAL043C 1304 + GAACAGTTCGAACTCCAACC N|436|K silent|AAC>AAT|N|436 PTA1 Pre-Trna Accumulation 785.0 0 0 0 0 0.014744890047643957 Q01329 0.9439849853515624 0.0 46.43493157929453 50.0 0.0 no 14 chrI_59828r 49 essential YAL043C 1202 + GCAAAAATACACCCTCAACA Q|402|E Q|402|* PTA1 Pre-Trna Accumulation 785.0 0 1 0 0 0.8022950866746096 Q01329 0.9590039849281312 0.03717512637376785 42.16126980398543 40.0 0.0 no 15 chrI_59935r 60 essential YAL043C 1095 + TCCGCGTTATTGTCTACTCT silent|TCC>TCG|S|366 silent|TCC>TCT|S|366 S|366|C S|366|F PTA1 Pre-Trna Accumulation 785.0 0 0 0 0 -0.22482319032051207 Q01329 0.945252001285553 0.9294660091400146 0.0384337492287159 0.04768448695540428 52.60454521520354 45.0 0.0 no 16 chrI_59970r 61 essential YAL043C 1060 + AACTAAAATACATCTCACTA L|355|V silent|CTA>TTA|L|355 PTA1 Pre-Trna Accumulation 785.0 0 0 0 0 0.3825168684100894 Q01329 0.9512209892272948 0.2875567376613617 33.6048675035039 25.0 0.0 no 17 chrI_60013 62 essential YAL043C 1020 - TTCTTGCTATTGCCCTTGGA K|346|N silent|AAG>AAA|K|346 S|345|T S|345|N PTA1 Pre-Trna Accumulation 785.0 0 0 0 0 -0.8664387506105695 Q01329 0.9355990290641784 0.9512869715690612 0.9536849856376648 0.0 0.5653834342956543 0.7476525306701659 54.86925774100626 45.0 0.0 no 18 chrI_60042 64 essential YAL043C 991 - GTTCAAAATTCCCTTGCTCT L|336|F silent|TTG>TTA|L|336 PTA1 Pre-Trna Accumulation 785.0 0 0 0 0 0.9456611346802112 Q01329 0.9587849974632264 0.018353071063756943 48.93003283877618 40.0 0.0 no 19 chrI_60230 69 essential YAL043C 803 - TCAAGTCAGACTTGCCCTCT L|274|F silent|TTG>TTA|L|274 D|273|H D|273|N PTA1 Pre-Trna Accumulation 785.0 0 0 0 0 0.7891131945919789 Q01329 0.9587849974632264 0.9486550092697144 0.956179976463318 0.02495268732309341 0.13356128334999084 0.498499870300293 55.01330540397049 50.0 0.0 no 20 chrI_60244r 70 essential YAL043C 786 + GACGCCAAGTTTCCCCTAGA D|263|E silent|GAC>GAT|D|263 A|264|G A|264|V PTA1 Pre-Trna Accumulation 785.0 0 0 0 0 -1.0200735745956335 Q01329 0.9532920122146606 0.9484469890594482 0.9504740238189696 0.0 0.5764071345329285 0.19539742171764374 56.78981939992241 55.00000000000001 0.0 no 21 chrI_60245r 71 essential YAL043C 785 + CGACGCCAAGTTTCCCCTAG D|263|E silent|GAC>GAT|D|263 A|264|G A|264|V PTA1 Pre-Trna Accumulation 785.0 0 0 0 0 -0.031197592284481438 Q01329 0.9532920122146606 0.9484469890594482 0.9504740238189696 0.0 0.5764071345329285 0.19539742171764374 56.28611736598111 60.0 0.0 no 22 chrI_60315r 73 essential YAL043C 715 + TATCCTTCGTCATCAAAAGA S|240|C S|240|F silent|TCC>TCG|S|240 silent|TCC>TCT|S|240 PTA1 Pre-Trna Accumulation 785.0 0 0 0 0 -0.104567266790662 Q01329 0.945252001285553 0.9294660091400146 0.012847572565078735 0.005258976016193628 41.73524487311254 35.0 0.0 no 23 chrI_60371 74 essential YAL043C 662 - CCATGTACTGTTCCTCAATT M|227|I M|227|I PTA1 Pre-Trna Accumulation 785.0 0 0 0 0 1.0485929198055055 Q01329 0.9553959965705872 0.9553959965705872 0.0 0.0 49.09563787433985 40.0 0.0 no 24 chrI_60371r 75 essential YAL043C 659 + CCTAATTGAGGAACAGTACA L|221|V silent|CTA>TTA|L|221 PTA1 Pre-Trna Accumulation 785.0 0 0 0 0 -0.866883691507261 Q01329 0.9512209892272948 0.0 42.06872216002796 40.0 0.0 no 25 chrI_60437 76 essential YAL043C 596 - AAGCCGGTTTGTTCAACACA A|205|P A|205|T silent|CCG>CCC|P|204 silent|CCG>CCA|P|204 PTA1 Pre-Trna Accumulation 785.0 0 0 0 0 0.3899006009007961 Q01329 0.9573720097541808 0.9523990154266356 0.20087024569511414 0.3793879449367523 48.82043407709215 45.0 0.0 no 26 chrI_60440 77 essential YAL043C 593 - CCGGTTTGTTCAACACAGGG silent|CCG>CCC|P|204 silent|CCG>CCA|P|204 PTA1 Pre-Trna Accumulation 785.0 0 0 0 0 -0.04619529734443527 Q01329 51.46542976255939 55.00000000000001 0.0 no 27 chrI_60449 79 essential YAL043C 584 - TCAACACAGGGTGGTTATCC L|201|F silent|TTG>TTA|L|201 silent|GTG>GTC|V|200 silent|GTG>GTA|V|200 PTA1 Pre-Trna Accumulation 785.0 0 0 0 0 -0.9350981728928432 Q01329 0.9587849974632264 0.031922493129968636 50.52528779160326 50.0 0.0 no 28 chrI_60496r 82 essential YAL043C 534 + TCGCAAACTAAATCACCCAG Q|180|E Q|180|* S|179|W S|179|L PTA1 Pre-Trna Accumulation 785.0 0 0 0 0 0.5700585520728575 Q01329 0.9590039849281312 0.9288619756698608 0.9298099875450134 0.16877537965774536 0.009593087248504162 0.22339273989200592 43.92482402809679 45.0 0.0 no 29 chrI_60597 84 essential YAL043C 436 - GACATCCGTTTCATCGTCAA V|152|L V|152|I D|151|H D|151|N PTA1 Pre-Trna Accumulation 785.0 0 0 0 0 0.25413146018287713 Q01329 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 0.56219482421875 0.7819755673408508 0.2165440022945404 0.2777679264545441 48.97169818967495 45.0 0.0 no 30 chrI_60713 87 essential YAL043C 320 - CAACCAGATCCAACACCAGC V|113|L V|113|I silent|CTG>CTC|L|112 silent|CTG>CTA|L|112 PTA1 Pre-Trna Accumulation 785.0 0 0 0 0 -0.3544311351881609 Q01329 0.9539830088615416 0.9574310183525084 0.03267206624150276 0.1647251695394516 51.02010897423982 55.00000000000001 0.0 no 31 chrI_60722r 89 essential YAL043C 308 + CGCTTCATACCCGCTGGTGT A|104|G A|104|V S|105|* S|105|L PTA1 Pre-Trna Accumulation 785.0 0 0 0 0 0.1945549629299686 Q01329 0.9484469890594482 0.9504740238189696 0.9298099875450134 0.3804877996444702 0.2877437472343445 0.6953974366188049 59.49210200759984 60.0 0.0 no 32 chrI_60793 92 essential YAL043C 240 - TGCGCCATAGCAAGAAGTAG silent|GCG>GCC|A|86 silent|GCG>GCA|A|86 A|86|P A|86|T PTA1 Pre-Trna Accumulation 785.0 0 0 0 0 -1.4043474598930026 Q01329 0.9573720097541808 0.9523990154266356 0.03269580006599426 0.07310466468334198 47.56993859162219 50.0 0.0 no 33 chrI_60797r 93 essential YAL043C 233 + TCTGCCACTACTTCTTGCTA L|79|V silent|CTG>TTG|L|79 P|80|A P|80|S PTA1 Pre-Trna Accumulation 785.0 0 0 0 0 0.6907910069911819 Q01329 0.9512209892272948 0.9562489986419678 0.9498909711837769 0.07503720372915268 0.3805967271327973 0.6036399602890015 53.45312174649712 45.0 0.0 no 34 chrI_60885 95 essential YAL043C 148 - AACTAACTGTGTAAAAAACT V|56|L V|56|I Q|54|H silent|CAG>CAA|Q|54 PTA1 Pre-Trna Accumulation 785.0 0 0 0 0 0.3471384620153968 Q01329 0.9539830088615416 0.9574310183525084 0.9570760130882264 0.4456499814987183 0.09776173532009123 0.21869619190692904 31.043941305256446 25.0 0.0 no 35 chrI_60937r 98 essential YAL043C 93 + ACGGCATCCATGTACCACAA T|32|R T|32|M A|33|G A|33|V PTA1 Pre-Trna Accumulation 785.0 0 0 0 0 0.4111993539622868 Q01329 0.9476869702339172 0.9502379894256592 0.9484469890594482 0.9504740238189696 0.035868465900421136 0.017632218077778816 0.4575277268886566 0.6790167093276978 51.633568668790424 50.0 0.0 no 36 chrI_60955 99 essential YAL043C 78 - GCCGTAGTTTCGAGCACCTT silent|ACG>ACC|T|32 silent|ACG>ACA|T|32 A|33|P A|33|T PTA1 Pre-Trna Accumulation 785.0 0 0 0 0 0.6817166060047855 Q01329 0.9573720097541808 0.9523990154266356 0.34061795473098755 0.7274436354637146 57.66096179145006 55.00000000000001 0.0 no 37 chrI_63082 110 essential YAL041W 242 + GCTATCCCAAAAGCAGCATC L|82|V silent|CTA>TTA|L|82 S|83|C S|83|F CDC24 Cell Division Cycle 854.0 0 0 0 0 -0.09844102089298636 P11433 0.1581275314092636 0.03067240118980408 0.03056959807872772 50.332292968228906 50.0 1.0 no 38 chrI_63088r 111 essential YAL041W 251 - GCAGTTCCTGATGCTGCTTT silent|CTG>CTC|L|90 silent|CTG>CTA|L|90 E|89|Q E|89|K CDC24 Cell Division Cycle 854.0 0 0 0 0 -0.5613550388178234 P11433 0.5768948197364807 0.9037977457046508 57.051208030410464 50.0 1.0 no 39 chrI_63181 116 essential YAL041W 341 + AGCTACCAGTCTCATGTCGA A|115|G A|115|V T|116|S T|116|I CDC24 Cell Division Cycle 854.0 0 0 0 0 1.1134996248386586 P11433 0.36001676321029663 0.2601291537284851 1.0 0.3228914141654968 53.90128095380396 50.0 1.0 no 40 chrI_63141 117 essential YAL041W 301 + GCGACTTGGCACCAACTTTA S|101|R silent|AGC>AGT|S|101 D|102|E silent|GAC>GAT|D|102 CDC24 Cell Division Cycle 854.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.3947281790777678 P11433 0.6629992723464966 0.7102574110031128 51.111497033487865 50.0 1.0 no 41 chrI_63256 124 essential YAL041W 416 + CACTTTACTGACTTTTAGTA T|140|S T|140|I CDC24 Cell Division Cycle 854.0 0 0 0 0 -0.17722416368394628 P11433 0.5577741265296936 0.06256461143493652 40.584603899552405 30.0 1.0 no 42 chrI_63525r 130 essential YAL041W 688 - TTCTAGCACTTTGACCAGCT E|236|Q E|236|K silent|GTG>GTC|V|234 silent|GTG>GTA|V|234 CDC24 Cell Division Cycle 854.0 0 0 0 0 -0.4702703746556726 P11433 0.289668470621109 0.5912004113197327 52.19496681250348 45.0 1.0 no 43 chrI_63588r 136 essential YAL041W 751 - TTGCTGTGTCTTACTCTTAG Q|256|H silent|CAG>CAA|Q|256 CDC24 Cell Division Cycle 854.0 0 0 0 0 0.1619701311125873 P11433 0.09471526741981506 47.66357693625247 40.0 1.0 no 44 chrI_63644r 138 essential YAL041W 807 - TGCTTCTTCGAAGACTGCTG K|275|N silent|AAG>AAA|K|275 K|274|N silent|AAG>AAA|K|274 CDC24 Cell Division Cycle 854.0 0 0 0 0 0.7340348217953203 P11433 0.453307569026947 0.4847913980484009 48.9142505414676 50.0 1.0 no 45 chrI_63794 141 essential YAL041W 954 + TACATGTTGTTCCCTAATTT Y|319|* silent|TAC>TAT|Y|319 CDC24 Cell Division Cycle 854.0 0 0 0 0 0.3778225870800249 P11433 44.921262300052774 30.0 1.0 no 46 chrI_63806r 142 essential YAL041W 969 - TCTATAGCATCACCCAAATT D|330|H D|330|N CDC24 Cell Division Cycle 854.0 0 0 0 0 0.4313195714743284 P11433 0.008132717572152616 0.02364371903240681 44.883695521855486 35.0 1.0 no 47 chrI_63852r 143 essential YAL041W 1015 - TACTAAAGCATTTATTTCCA V|345|L V|345|I CDC24 Cell Division Cycle 854.0 0 0 0 0 0.7185983310996229 P11433 0.28446507453918457 0.53838050365448 39.14401930183817 25.0 1.0 no 48 chrI_63981 147 essential YAL041W 1141 + CTTCAACTTTGCACAAGATG S|382|* S|382|L T|383|S T|383|I CDC24 Cell Division Cycle 854.0 0 0 0 0 -0.5167571581716676 P11433 0.10788359493017197 0.9200011491775512 0.2160761207342148 41.421789515091746 40.0 1.0 no 49 chrI_63982 148 essential YAL041W 1142 + TTCAACTTTGCACAAGATGA S|382|* S|382|L T|383|S T|383|I CDC24 Cell Division Cycle 854.0 0 0 0 0 0.166428967677839 P11433 0.10788359493017197 0.9200011491775512 0.2160761207342148 40.827339262392115 35.0 1.0 no 50 chrI_64056 150 essential YAL041W 1216 + TCCTTTATAAACCCGTGCAA L|407|V L|407|F F|406|L silent|TTC>TTT|F|406 CDC24 Cell Division Cycle 854.0 0 0 0 0 1.2713391079724734 P11433 0.12050400674343108 0.05126025155186653 0.03282991424202919 47.247656035194844 40.0 1.0 no 51 chrI_64057r 151 essential YAL041W 1220 - GCCTTTGCACGGGTTTATAA R|413|T R|413|K R|413|S silent|AGG>AGA|R|413 CDC24 Cell Division Cycle 854.0 0 0 0 0 -0.679149531028836 P11433 0.0 0.0 0.0 1.395359992980957 0.1717199981212616 1.731760025024414 50.689196692939454 45.0 1.0 no 52 chrI_64067r 152 essential YAL041W 1230 - TATCTACAAAGCCTTTGCAC R|416|T R|416|K C|415|S C|415|Y CDC24 Cell Division Cycle 854.0 0 0 0 0 0.07258972748794831 P11433 0.020943664014339447 1.0 0.0 0.0 0.250220000743866 0.056239999830722816 0.3006600141525269 4.102240085601807 44.93286696043441 40.0 1.0 no 53 chrI_64091r 154 essential YAL041W 1254 - AGCAATTCTTTGACCAACAG L|424|F silent|TTG>TTA|L|424 CDC24 Cell Division Cycle 854.0 0 0 0 0 -4.681491336903191 P11433 0.0 43.45684638407971 40.0 1.0 yes 54 chrI_64318 156 essential YAL041W 1478 + TTCAACAACAAATAGCTCCT S|494|* S|494|L T|495|R T|495|I CDC24 Cell Division Cycle 854.0 0 0 0 0 -1.207350943767454 P11433 0.13047583401203156 0.09894151240587233 0.03322755917906761 41.09644884214345 35.0 1.0 no 55 chrI_64472 158 essential YAL041W 1632 + TCGAACATAACGGACAACAA S|545|W S|545|L N|546|K silent|AAC>AAT|N|546 CDC24 Cell Division Cycle 854.0 0 0 0 0 -0.17172332100919052 P11433 37.81104470631527 40.0 1.0 no 56 chrI_64500 160 essential YAL041W 1660 + CTCACCACAGTTACCATAAG H|555|D H|555|Y H|555|Q silent|CAC>CAT|H|555 CDC24 Cell Division Cycle 854.0 0 1 0 0 0.16570845049365346 P11433 0.6470318436622621 0.05990400165319443 0.535728394985199 46.539737139521826 45.0 1.0 no 57 chrI_64513r 162 essential YAL041W 1676 - TACTATTGCTATGCCTCTTA S|565|T S|565|N CDC24 Cell Division Cycle 854.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.4968041896995433 P11433 0.5758579969406128 0.6442697644233704 47.463847136364 35.0 1.0 no 58 chrI_64661 163 essential YAL041W 1821 + GAACCTAAGCTGGATCTAAG P|609|A P|609|S P|609|R P|609|L CDC24 Cell Division Cycle 854.0 0 0 0 0 0.6644228087350982 P11433 0.6499572992324829 0.9192228317260742 0.3342218399047852 0.3355023264884949 42.934828178396906 45.0 1.0 no 59 chrI_64664r 164 essential YAL041W 1827 - CGACCTCTTAGATCCAGCTT G|615|A G|615|D G|615|R G|615|S CDC24 Cell Division Cycle 854.0 0 0 0 0 -1.5800184616743471 P11433 0.0 0.0 0.0 0.0 53.4174523732903 50.0 1.0 no 60 chrI_71985r 169 essential YAL038W 202 - GTACAATTCTTCGGACTTTC L|73|F silent|TTG>TTA|L|73 CDC19 Cell Division Cycle 500.0 0 1 0 0 1.241086294897472 P00549 0.04129448160529137 0.2648000121116638 44.342487285074014 40.0 1.0 no 61 chrI_72391 179 essential YAL038W 605 + TGTCAAGAACGGTGTCCACA silent|GTC>GTG|V|203 silent|GTC>GTT|V|203 CDC19 Cell Division Cycle 500.0 0 0 0 0 0.3000679966701015 P00549 49.15643465955037 50.0 1.0 no 62 chrI_72453r 181 essential YAL038W 670 - TTCACCCAAGACTTCTCTGA E|230|Q E|230|K G|229|A G|229|D CDC19 Cell Division Cycle 500.0 0 1 0 0 0.6094812475509221 P00549 0.3793769776821137 0.5471231341362001 0.018727563321590424 0.01082935743033886 50.33008371478768 45.0 1.0 no 63 chrI_72463 182 essential YAL038W 677 + AGTCTTGGGTGAACAAGGTA silent|GTC>GTG|V|227 silent|GTC>GTT|V|227 CDC19 Cell Division Cycle 500.0 0 0 0 0 0.2254656601470416 P00549 46.62512380913489 45.0 1.0 no 64 chrI_72573r 183 essential YAL038W 790 - TTCAATACCCAAGTCACCTC E|270|Q E|270|K CDC19 Cell Division Cycle 500.0 0 1 0 0 -1.8501808553050312 P00549 0.033312786370515816 0.003832372836768627 49.470949517575654 45.0 1.0 no 65 chrI_72595 184 essential YAL038W 809 + AATCCCAGCCCCAGAAGTCT I|271|M silent|ATC>ATT|I|271 P|272|A P|272|S CDC19 Cell Division Cycle 500.0 0 1 0 0 -0.16048353510326613 P00549 0.0015423200093209743 0.07428549975156784 0.014471933245658875 -2.38759994506836 58.62542784800786 55.00000000000001 1.0 no 66 chrI_72622r 187 essential YAL038W 839 - ACTTAGCAATCAATTTCTTT K|286|N silent|AAG>AAA|K|286 A|285|P A|285|T CDC19 Cell Division Cycle 500.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.3370532621114092 P00549 0.02599813044071197 0.05532962083816528 0.2244122475385666 2.453200101852417 -0.21320000290870667 39.26021281175576 25.0 1.0 no 67 chrI_76488r 201 high_effect YAL035W 64 - ACTGATTTCTTCGTTCTGGG S|28|T S|28|N FUN12 Function Unknown Now 1002.0 0 0 0 0 0.3646558772387492 P39730 0.5742859840393066 0.5279209613800049 49.06912834942813 45.0 1.0 no 68 chrI_76492r 202 high_effect YAL035W 68 - TGGCACTGATTTCTTCGTTC A|29|P A|29|T S|28|T S|28|N FUN12 Function Unknown Now 1002.0 0 0 0 0 -0.10996080029264392 P39730 0.3300847411155701 0.6299148797988892 0.5742859840393066 0.5279209613800049 49.86669277232016 45.0 1.0 no 69 chrI_76596r 209 high_effect YAL035W 172 - AGACATGAAGTCGCCTTCAA M|63|I M|63|I FUN12 Function Unknown Now 1002.0 0 1 0 0 -0.6514459717343285 P39730 0.5732902884483337 0.5732902884483337 46.99105656012455 45.0 1.0 no 70 chrI_76682r 210 high_effect YAL035W 258 - TCCTTCTTGGACTTTAGTAT K|92|N silent|AAG>AAA|K|92 E|93|Q E|93|K FUN12 Function Unknown Now 1002.0 0 1 0 0 -0.35710439162913776 P39730 0.09607184678316116 0.15267090499401093 0.40843427181243896 47.24338725494004 35.0 1.0 no 71 chrI_76758r 212 high_effect YAL035W 334 - TTGCTGTTGGGCCTTCTTCC Q|117|H silent|CAG>CAA|Q|117 FUN12 Function Unknown Now 1002.0 0 0 0 0 -0.37388271541170015 P39730 0.07446249574422836 60.872950105546074 55.00000000000001 1.0 no 72 chrI_76771r 213 high_effect YAL035W 347 - TCTCCTTTTGAGCTTGCTGT E|122|Q E|122|K E|122|D silent|GAG>GAA|E|122 FUN12 Function Unknown Now 1002.0 0 0 0 0 -0.7025681551982409 P39730 0.3393099308013916 0.3556176126003265 0.4712676107883453 55.274967836489346 45.0 1.0 no 73 chrI_76861r 216 high_effect YAL035W 437 - CACTTTCACCTTTAGATTTT S|152|T S|152|N E|151|Q E|151|K FUN12 Function Unknown Now 1002.0 0 0 0 0 0.5142740535680037 P39730 0.5851215720176697 0.5059545636177063 0.5749445557594299 0.9108113646507264 43.728568290338046 30.0 1.0 no 74 chrI_77217r 224 high_effect YAL035W 793 - TCCATCCTTCTTGGCCAGAC G|271|R G|271|R G|271|A G|271|E FUN12 Function Unknown Now 1002.0 0 0 0 0 0.32155529110237324 P39730 0.4584105014801026 0.4584105014801026 0.8455390334129333 1.0 58.511230355788705 55.00000000000001 1.0 no 75 chrI_77252r 225 high_effect YAL035W 828 - TTGCTGTAAACAACCTTCTT S|282|T S|282|N FUN12 Function Unknown Now 1002.0 0 0 0 0 -0.08285830640302022 P39730 0.6663315296173096 0.5818713903427124 43.5832865908269 35.0 1.0 no 76 chrI_77304r 228 high_effect YAL035W 880 - GTCAGATTTAATGGCTTCGG D|300|H D|300|N FUN12 Function Unknown Now 1002.0 0 1 0 0 -0.8803530650024649 P39730 0.07415656000375748 0.2929966747760773 46.506179821075925 45.0 1.0 no 77 chrI_77482r 232 high_effect YAL035W 1058 - CTTCTTCTTCGCCTTGATTT E|359|Q E|359|K E|358|Q E|358|K FUN12 Function Unknown Now 1002.0 0 0 0 0 -0.1030653228407908 P39730 0.5095205903053284 0.9305447340011596 0.4729290902614594 0.8412115573883057 51.105871896436675 40.0 1.0 no 78 chrI_77642r 233 high_effect YAL035W 1218 - TGACCCAAAATACAACAAAT G|412|A G|412|D G|412|R G|412|S FUN12 Function Unknown Now 1002.0 0 0 0 0 0.13393880928440782 P39730 0.0 0.0 0.0 0.0 3.2232000827789307 18.434545516967773 19.869609832763672 6.3231401443481445 35.556065616386256 30.0 1.0 no 79 chrI_77699 235 high_effect YAL035W 1272 + ATCAGACAAACCAACGTTCA I|425|M silent|ATC>ATT|I|425 Q|427|E Q|427|* FUN12 Function Unknown Now 1002.0 0 0 0 0 0.4443592355802832 P39730 0.003038982627913356 0.019799111410975456 -0.8687199950218201 -0.17499999701976776 42.53256236347164 40.0 1.0 no 80 chrI_77702 236 high_effect YAL035W 1275 + AGACAAACCAACGTTCAAGG Q|427|E Q|427|* FUN12 Function Unknown Now 1002.0 0 0 0 0 -1.0919453802242118 P39730 0.019799111410975456 -0.17499999701976776 41.369219952751045 45.0 1.0 no 81 chrI_77709r 238 high_effect YAL035W 1285 - AGCTTCACCACCTTGAACGT A|435|P A|435|T E|434|Q E|434|K FUN12 Function Unknown Now 1002.0 0 0 0 0 -0.649876443595885 P39730 0.00631261896342039 0.007320540025830269 0.0 0.0 5.377600193023682 1.7187000513076782 -0.6410999894142151 -0.7872999906539917 52.79115913792981 50.0 1.0 no 82 chrI_77757r 239 high_effect YAL035W 1333 - AGCGTCGATGGGGAAATAAG A|451|P A|451|T D|450|H D|450|N FUN12 Function Unknown Now 1002.0 0 0 0 0 0.5346644856217921 P39730 0.016477562487125397 0.1377732753753662 0.014134863391518591 0.04121161624789238 1.6851600408554075 2.05787992477417 0.8012999892234802 0.8992400169372559 43.5497892231561 50.0 1.0 no 83 chrI_77764 240 high_effect YAL035W 1337 + TTTCCCCATCGACGCTATTA F|447|L silent|TTC>TTT|F|447 P|448|A P|448|S FUN12 Function Unknown Now 1002.0 0 0 0 0 -0.7129093395903412 P39730 0.03234601765871048 0.0 0.0 1.2174400091171265 2.972899913787842 3.318919897079468 52.622682378577615 45.0 1.0 no 84 chrI_77816 242 high_effect YAL035W 1389 + AAACAAACTTTTGATGTCCC Q|465|E Q|465|* FUN12 Function Unknown Now 1002.0 0 0 0 0 -0.20249116867395253 P39730 0.27741193771362305 0.3709999918937683 40.696286779387606 35.0 1.0 no 85 chrI_78288r 251 high_effect YAL035W 1864 - AGACAAGTACATCAATTGTT L|627|F silent|TTG>TTA|L|627 FUN12 Function Unknown Now 1002.0 0 0 0 0 0.5478456865948879 P39730 0.012774374336004255 0.192100003361702 38.267173355901434 30.0 1.0 no 86 chrI_78310 252 high_effect YAL035W 1883 + TCACGTGGAAGCAACCATTT H|629|Q silent|CAC>CAT|H|629 H|629|D H|629|Y FUN12 Function Unknown Now 1002.0 0 0 0 0 -0.4039822902053936 P39730 0.07187175750732422 0.1959180533885956 0.008059913292527199 -0.3659600019454956 -0.08058000355958939 -0.6231200098991394 47.244528034290504 45.0 1.0 no 87 chrI_78324r 253 high_effect YAL035W 1900 - TACGACTTTCACTTCCAAAA V|640|L V|640|I V|639|L V|639|I FUN12 Function Unknown Now 1002.0 0 0 0 0 0.16006427756028982 P39730 0.016481904312968254 1.0 0.015535060316324234 0.018586503341794014 0.7097200155258179 0.005439999978989364 -0.5884000062942505 -0.4815399944782257 41.07661457879203 35.0 1.0 no 88 chrI_78381r 256 high_effect YAL035W 1957 - ACCTTCTCTCAAGTAACCGT G|659|R G|659|S G|659|A G|659|D FUN12 Function Unknown Now 1002.0 0 0 0 0 -0.8853775771569292 P39730 0.0 0.0 0.0 0.0 3.201580047607422 3.189840078353882 3.205519914627075 3.63673996925354 50.43910389953186 45.0 1.0 no 89 chrI_78406r 258 high_effect YAL035W 1982 - TCATACCACACAGTACAATA M|667|I M|667|I G|666|A G|666|D FUN12 Function Unknown Now 1002.0 0 0 0 0 -0.4770582048271819 P39730 0.11009454727172853 0.11009454727172853 0.023766640573740002 0.0069986339658498755 0.8770400285720825 0.8770400285720825 2.437040090560913 11.07755184173584 41.86830576289208 35.0 1.0 no 90 chrI_78473r 259 high_effect YAL035W 2049 - TTCAAACGTAGTTCACGTAA L|689|F silent|TTG>TTA|L|689 R|688|P R|688|H FUN12 Function Unknown Now 1002.0 0 0 0 0 -0.2857301974479207 P39730 0.010949666611850262 0.0 0.0 -0.24918000400066376 -0.6979600191116333 0.4412199854850769 39.92792462814856 35.0 1.0 no 91 chrI_78570r 261 high_effect YAL035W 2146 - TAGCAGCCTAGAACCAGAAA silent|CTG>CTC|L|721 silent|CTG>CTA|L|721 R|720|S silent|AGG>AGA|R|720 FUN12 Function Unknown Now 1002.0 0 0 0 0 1.34715402523878 P39730 0.08483661711215973 1.4670000076293943 46.01191211272339 45.0 1.0 no 92 chrI_78666r 264 high_effect YAL035W 2242 - ACCTTTACCAGTTGTGTCAA G|754|R G|754|S G|754|A G|754|D FUN12 Function Unknown Now 1002.0 0 0 0 0 0.29726060435290463 P39730 0.0 0.0 0.0 0.0 19.2261905670166 11.478360176086426 7.188300132751465 22.011913299560547 49.69431026504668 40.0 1.0 no 93 chrI_79744 265 essential YAL034W-A 26 + CTCAATATTGACAGAGCATT S|10|* S|10|L MTW1 Mis TWelve-like 289.0 0 0 0 0 0.4925488765881521 P39731 0.9298099875450134 0.39677944779396057 41.03165233989785 35.0 1.0 no 94 chrI_79740r 266 essential YAL034W-A 25 - ATGCTCTGTCAATATTGAGG E|14|D silent|GAG>GAA|E|14 E|14|Q E|14|K MTW1 Mis TWelve-like 289.0 0 0 0 0 -1.0076861839858533 P39731 0.94931298494339 0.956179976463318 0.9475290179252625 0.061198059469461434 0.25672200322151184 0.027569055557250977 44.12916635370237 40.0 1.0 no 95 chrI_79745 267 essential YAL034W-A 27 + TCAATATTGACAGAGCATTT S|10|* S|10|L MTW1 Mis TWelve-like 289.0 0 0 0 0 0.2317956855634552 P39731 0.9298099875450134 0.39677944779396057 39.45813346581906 30.0 1.0 no 96 chrI_79822 269 essential YAL034W-A 104 + GTACAAGTGCACTGCTGCCA Y|36|* silent|TAC>TAT|Y|36 MTW1 Mis TWelve-like 289.0 0 0 0 0 -6.562390118406059 P39731 55.66320368043733 55.00000000000001 1.0 yes 97 chrI_79912 271 essential YAL034W-A 194 + TGCTAAGTTGGAATCACTTT A|66|G A|66|V MTW1 Mis TWelve-like 289.0 0 0 0 0 0.4168880890332076 P39731 0.9484469890594482 0.9504740238189696 0.16566893458366394 0.015381230972707272 42.60525578040625 35.0 1.0 no 98 chrI_79999r 273 essential YAL034W-A 284 - TGGCGTCCAAATACTCTTCA A|101|P A|101|T D|100|H D|100|N MTW1 Mis TWelve-like 289.0 0 0 0 0 -2.352567926708931 P39731 0.9573720097541808 0.9523990154266356 0.9486550092697144 0.956179976463318 0.2818848490715027 0.573039174079895 0.028184115886688232 0.05889564752578736 49.03559372019385 45.0 1.0 yes 99 chrI_80041r 275 essential YAL034W-A 326 - CTACAATGACCAGATCCTTT V|115|L V|115|I MTW1 Mis TWelve-like 289.0 0 1 0 0 -0.32531920118272045 P39731 0.9539830088615416 0.9574310183525084 0.2992716729640961 0.18576039373874664 45.91553890156467 40.0 1.0 no 100 chrI_80174 276 essential YAL034W-A 456 + AGACTGTTGTTTACGATAAG L|154|V silent|CTG>TTG|L|154 MTW1 Mis TWelve-like 289.0 0 0 0 0 -1.1270868832720895 P39731 0.9512209892272948 0.9557827711105348 38.90527063441067 35.0 1.0 no 101 chrI_82753 282 essential YAL033W 47 + ACCTACAGACACCAACGTTG P|17|R P|17|L P|17|A P|17|S POP5 Processing Of Precursor RNAs 173.0 0 0 0 0 0.9314086553928064 P28005 0.8839269876480103 0.8799740076065063 0.9154000282287598 0.9027060270309448 0.1807573288679123 0.1301208734512329 0.3314134478569031 0.3061860501766205 47.841656878546075 50.0 1.0 no 102 chrI_82823r 286 essential YAL033W 120 - GACTTTATGGACACATCCGC K|46|N silent|AAG>AAA|K|46 POP5 Processing Of Precursor RNAs 173.0 1 Series([], Name: modification, dtype: object) 0 0 0 -1.0570422010933056 P28005 0.8459349870681763 0.012776804156601429 49.33572133519209 50.0 1.0 no 103 chrI_82963r 292 essential YAL033W 260 - CGCAATCCTCTCGATGGCAT C|93|S C|93|Y D|92|H D|92|N POP5 Processing Of Precursor RNAs 173.0 0 0 0 0 -0.0050564451648030286 P28005 0.92536598443985 0.9475650191307068 0.9605600237846376 0.944997012615204 0.429545134305954 1.0 0.26878708600997925 0.4991904199123383 53.463804488456496 55.00000000000001 1.0 no 104 chrI_83070r 296 essential YAL033W 367 - AAACTGCTCTATTTTCTTGA Q|128|H silent|CAG>CAA|Q|128 E|127|D silent|GAG>GAA|E|127 POP5 Processing Of Precursor RNAs 173.0 0 1 0 0 0.5384952046009772 P28005 0.8745480179786682 0.8785939812660217 0.025173088535666462 0.0 41.17253770501554 30.0 1.0 no 105 chrI_83791 303 essential YAL032C 664 - AAGCCGCTTCAATTCCATTT silent|CGG>CGC|R|227 silent|CGG>CGA|R|227 R|227|P R|227|Q PRP45 Pre-mRNA Processing 379.0 0 0 0 0 0.6917850354845932 P28004 0.020641028881073 0.06093499064445496 49.58876584695247 40.0 0.0 no 106 chrI_83866 304 essential YAL032C 589 - CTTCATAAACCCATCGTTGA M|202|I M|202|I PRP45 Pre-mRNA Processing 379.0 0 0 0 0 0.0289894099074432 P28004 0.5630868673324585 0.5630868673324585 45.56659581998309 40.0 0.0 no 107 chrI_84012 307 essential YAL032C 443 - TATCATTGCTGCCATCCATA D|154|H D|154|N PRP45 Pre-mRNA Processing 379.0 0 0 0 0 0.9097715010857066 P28004 0.12737107276916504 0.4892945885658264 51.04437580346893 40.0 0.0 no 108 chrI_84043 311 essential YAL032C 412 - CACGACTTCGTCGTTTTCTG V|144|L V|144|M V|143|L V|143|I PRP45 Pre-mRNA Processing 379.0 0 0 0 0 -2.129954291504267 P28004 0.24445249140262604 0.07233844697475432 0.29302453994750977 0.18491961061954496 48.89075241141597 50.0 0.0 yes 109 chrI_84083 313 essential YAL032C 372 - GCCTTCTTCCCAACGAACCT K|130|N silent|AAG>AAA|K|130 A|131|P A|131|T PRP45 Pre-mRNA Processing 379.0 0 0 0 0 -0.2190244600996602 P28004 0.029609084129333493 0.24989335238933566 0.5365772843360901 56.558695098094006 55.00000000000001 0.0 no 110 chrI_84135r 319 essential YAL032C 317 + GAACAACAGCCACCATATTG N|107|K silent|AAC>AAT|N|107 N|108|K silent|AAC>AAT|N|108 PRP45 Pre-mRNA Processing 379.0 0 0 0 0 0.22802254853874904 P28004 0.9271290302276612 1.0 45.037335842823886 45.0 0.0 no 111 chrI_84177r 321 essential YAL032C 275 + GTACGTCACCGAAACACATC Y|93|* silent|TAC>TAT|Y|93 silent|GTC>GTG|V|94 silent|GTC>GTT|V|94 PRP45 Pre-mRNA Processing 379.0 0 0 0 0 -0.2651875767305587 P28004 45.77697837733365 50.0 0.0 no 112 chrI_84210r 322 essential YAL032C 242 + ACTAGCCAACTCAAATAACA L|82|V silent|CTA>TTA|L|82 A|83|G A|83|V PRP45 Pre-mRNA Processing 379.0 0 0 0 0 -0.472456111742241 P28004 0.7020547389984131 0.34916290640830994 0.2653363943099976 39.920561174664435 35.0 0.0 no 113 chrI_84247r 324 essential YAL032C 205 + GAACCAAGTCATACATTCAG T|70|S T|70|I silent|ACC>ACG|T|70 silent|ACC>ACT|T|70 PRP45 Pre-mRNA Processing 379.0 0 0 0 0 0.6955104983182765 P28004 0.0 0.0 41.74077480711702 40.0 0.0 no 114 chrI_100812 336 essential YAL025C 314 - ATCTCTGTTTACACTTATGA R|111|T R|111|K Q|110|H silent|CAG>CAA|Q|110 MAK16 MAintenance of Killer 306.0 0 0 0 0 -1.0814885435035413 P10962 0.0 0.0 0.0019886328373104334 42.096185414266074 30.0 0.0 no 115 chrI_100846r 337 essential YAL025C 277 + TCGACGAACACCTACTACAT I|93|M silent|ATC>ATT|I|93 D|94|E silent|GAC>GAT|D|94 MAK16 MAintenance of Killer 306.0 0 0 0 0 -0.05925303364074816 P10962 0.004181332886219025 0.057430226355791085 44.77975109580973 45.0 0.0 no 116 chrI_100881r 338 essential YAL025C 242 + ACTATCCAAAAATTACACGA L|82|V silent|CTA>TTA|L|82 S|83|C S|83|F MAK16 MAintenance of Killer 306.0 0 0 0 0 0.4021330010522979 P10962 0.0 0.00854515191167593 0.008902883157134056 36.51830409074449 30.0 0.0 no 117 chrI_100914r 339 essential YAL025C 209 + GCACACTCCTGCCAAGTTAT H|71|Q silent|CAC>CAT|H|71 H|71|D H|71|Y MAK16 MAintenance of Killer 306.0 0 0 0 0 -0.20601304448460087 P10962 0.07043616473674774 0.11245522648096083 0.030039850622415543 54.379275710285576 50.0 0.0 no 118 chrI_100915r 340 essential YAL025C 208 + CGCACACTCCTGCCAAGTTA H|71|D H|71|Y H|71|Q silent|CAC>CAT|H|71 MAK16 MAintenance of Killer 306.0 0 0 0 0 0.5941070243944787 P10962 0.11245522648096083 0.030039850622415543 0.07043616473674774 55.1299627669099 55.00000000000001 0.0 no 119 chrI_100972r 343 essential YAL025C 151 + CAACAGTGAAGTGTGACAAT T|52|R T|52|I MAK16 MAintenance of Killer 306.0 0 1 0 0 -3.363230166085998 P10962 0.0 0.0 39.71773764715692 40.0 0.0 yes 120 chrI_101060 347 essential YAL025C 66 - CTGCAAAAATTTTGACCATT C|28|S C|28|Y MAK16 MAintenance of Killer 306.0 0 0 0 0 -0.19303306143309845 P10962 0.0 0.0 38.467158189217464 30.0 0.0 no 121 chrI_101085r 348 essential YAL025C 38 + TTTCTGCTCTCATAGAATTA F|14|L silent|TTC>TTT|F|14 C|15|W silent|TGC>TGT|C|15 MAK16 MAintenance of Killer 306.0 0 0 0 0 -0.2548984726736182 P10962 0.012117433361709118 0.0 41.872860018465026 30.0 0.0 no 122 chrI_101119 349 essential YAL025C 7 - CACTTGCCAAACAATTTCGT V|9|L V|9|M W|7|C W|7|* MAK16 MAintenance of Killer 306.0 0 0 0 0 0.7176538801569794 P10962 0.19922472536563876 0.015656715258955956 0.0 44.338866270133344 40.0 0.0 no 123 chrI_111601 353 high_effect YAL021C 1739 - TCTTGGCTCTTGCCTTTGCA K|586|N silent|AAG>AAA|K|586 A|585|P A|585|T CCR4 Carbon Catabolite Repression 837.0 0 0 0 0 -0.4543673550690779 P31384 0.007002714090049267 0.03477727994322777 0.036595318466424935 58.72994882122362 50.0 0.0 no 124 chrI_111636 355 high_effect YAL021C 1704 - TAACCGTGCTTGTCCAATAG G|574|A G|574|D G|574|R G|574|S CCR4 Carbon Catabolite Repression 837.0 0 0 0 0 0.004736277539760816 P31384 0.012199314311146736 0.15366995334625244 0.005344522651284933 0.018789758905768398 47.40535654277977 45.0 0.0 no 125 chrI_111752r 356 high_effect YAL021C 1585 + GGGCGTTAAGTTGGGATTAC A|530|G A|530|V CCR4 Carbon Catabolite Repression 837.0 0 0 0 0 -0.5155805942014086 P31384 0.0 0.0 48.636064513549464 50.0 0.0 no 126 chrI_111772r 360 high_effect YAL021C 1565 + GTACCGTTACACACCGTCGT Y|523|* silent|TAC>TAT|Y|523 R|524|G R|524|C CCR4 Carbon Catabolite Repression 837.0 0 0 0 0 -0.05608065580197314 P31384 0.9387684464454652 0.026879111304879192 54.628031533280144 55.00000000000001 0.0 no 127 chrI_111851r 362 high_effect YAL021C 1486 + TGGCCACCGATTTAGCCAAG A|497|G A|497|V silent|GCC>GCG|A|497 silent|GCC>GCT|A|497 CCR4 Carbon Catabolite Repression 837.0 0 0 0 0 0.3842385266101721 P31384 0.4118106663227081 0.2694203555583954 53.69760450068503 55.00000000000001 0.0 no 128 chrI_112083 374 high_effect YAL021C 1257 - CACAGGTTCCCAAACTCCCA silent|CTG>CTC|L|425 silent|CTG>CTA|L|425 CCR4 Carbon Catabolite Repression 837.0 0 0 0 0 0.10324227137357787 P31384 55.90544975524409 55.00000000000001 0.0 no 129 chrI_112091r 375 high_effect YAL021C 1246 + CCACATTACCATGGGAGTTT T|417|R T|417|I silent|ACC>ACG|T|416 silent|ACC>ACT|T|416 CCR4 Carbon Catabolite Repression 837.0 0 0 0 0 -0.2830201328514504 P31384 0.013916425406932829 0.009844087064266205 50.4504058228265 45.0 0.0 no 130 chrI_112152 378 high_effect YAL021C 1188 - AAACATGAGCCTAGTTCCGC C|402|S C|402|Y CCR4 Carbon Catabolite Repression 837.0 0 0 0 0 0.3664235335627136 P31384 0.010096067562699318 0.00880836509168148 50.22283606066657 50.0 0.0 no 131 chrI_112491 391 high_effect YAL021C 849 - AGCTCTATCTTGGGAGTCAA E|289|D silent|GAG>GAA|E|289 E|289|Q E|289|K CCR4 Carbon Catabolite Repression 837.0 0 1 0 0 0.6059503819586316 P31384 0.5706471800804138 0.5340003967285156 0.8191782236099243 49.82551669822817 45.0 0.0 no 132 chrI_112560r 393 high_effect YAL021C 777 + GCAAAGAAACAACAACCTAC A|260|G A|260|V CCR4 Carbon Catabolite Repression 837.0 0 1 0 0 -0.14875620540891465 P31384 0.07666482031345367 0.25668829679489136 37.04608430826022 40.0 0.0 no 133 chrI_112574 394 high_effect YAL021C 766 - TTTCTTTGCTGTCTTGCTGT K|261|N silent|AAG>AAA|K|261 CCR4 Carbon Catabolite Repression 837.0 0 1 0 0 0.6217156978654247 P31384 0.5420987606048584 52.995762160432044 40.0 0.0 no 134 chrI_112845r 407 high_effect YAL021C 492 + GCAGTGTCCGCACAATCTCT A|165|G A|165|V CCR4 Carbon Catabolite Repression 837.0 0 0 0 0 -0.14849773489812726 P31384 0.3279465436935425 0.20874564349651334 56.374163239543684 55.00000000000001 0.0 no 135 chrI_112846r 408 high_effect YAL021C 491 + TGCAGTGTCCGCACAATCTC A|165|G A|165|V CCR4 Carbon Catabolite Repression 837.0 0 0 0 0 -0.03775144410591042 P31384 0.3279465436935425 0.20874564349651334 54.467519303417596 55.00000000000001 0.0 no 136 chrI_112921r 411 high_effect YAL021C 416 + CCCTTTATTACACCCGCACT P|140|R P|140|L P|140|A P|140|S CCR4 Carbon Catabolite Repression 837.0 0 0 0 0 0.0446382507985133 P31384 55.69547085803731 50.0 0.0 no 137 chrI_112994r 418 high_effect YAL021C 343 + CAGCCGCAGTAAATTCTATA A|116|G A|116|V silent|GCC>GCG|A|116 silent|GCC>GCT|A|116 CCR4 Carbon Catabolite Repression 837.0 0 0 0 0 0.8548630737110923 P31384 45.19997072787788 40.0 0.0 no 138 chrI_113127r 424 high_effect YAL021C 210 + TTGCTCGACCAATTGGCTAA L|72|V L|72|F silent|CTC>CTG|L|72 silent|CTC>CTT|L|72 CCR4 Carbon Catabolite Repression 837.0 0 0 0 0 0.6509096977775773 P31384 48.230099310620574 45.0 0.0 no 139 chrI_113203r 429 high_effect YAL021C 134 + GCTCACCGGGATACCTCCAC silent|CTC>CTG|L|46 silent|CTC>CTT|L|46 L|46|V L|46|F CCR4 Carbon Catabolite Repression 837.0 0 0 0 0 -0.3680004738673516 P31384 59.93021335151075 65.0 0.0 no 140 chrI_113216r 430 high_effect YAL021C 121 + TACACATGAACCAGCTCACC H|42|D H|42|Y H|42|Q silent|CAC>CAT|H|42 CCR4 Carbon Catabolite Repression 837.0 0 0 0 0 -1.5383820315951724 P31384 49.38529448775364 50.0 0.0 no 141 chrI_113279r 435 high_effect YAL021C 58 + AGCAGCAACAGCAGCATGCC Q|21|E Q|21|* Q|22|E Q|22|* CCR4 Carbon Catabolite Repression 837.0 0 0 0 0 -0.03575976326072103 P31384 57.09144113176803 60.0 0.0 no 142 chrI_142692 444 essential YAL003W 152 + GTTCAACCACATCGCTTCCA F|52|L silent|TTC>TTT|F|52 N|53|K silent|AAC>AAT|N|53 EFB1 Elongation Factor Beta 206.0 0 1 0 0 0.6855017028916326 P32471 0.033997002989053726 1.0 53.90905319747975 50.0 1.0 no 143 chrI_142751r 448 essential YAL003W 214 - ATCTTCTTCTTCTTCGGCAG D|78|H D|78|N E|77|Q E|77|K EFB1 Elongation Factor Beta 206.0 0 0 0 0 -0.4858662718947512 P32471 0.007331045810133219 0.07230176776647568 0.09883849322795868 0.16800445318222046 51.660403164527686 45.0 1.0 no 144 chrI_142908 449 essential YAL003W 368 + CACTCTAGATGTCAAGCCAT T|124|S T|124|I L|125|V silent|CTA>TTA|L|125 EFB1 Elongation Factor Beta 206.0 0 1 0 0 0.514434493814691 P32471 0.006951949093490839 0.8325892090797424 0.00568172475323081 1.5589200258255005 -0.5508999824523926 1.0775400400161743 48.554748001917524 45.0 1.0 no 145 chrI_142907 450 essential YAL003W 367 + TCACTCTAGATGTCAAGCCA T|124|S T|124|I silent|GTC>GTG|V|123 silent|GTC>GTT|V|123 EFB1 Elongation Factor Beta 206.0 0 1 0 0 -3.205811854423285 P32471 0.006951949093490839 0.8325892090797424 1.5589200258255005 -0.5508999824523926 49.67189061424165 45.0 1.0 yes 146 chrI_142973r 453 essential YAL003W 436 - GGTCAAACCTTCCATTTCGA L|151|F silent|TTG>TTA|L|151 EFB1 Elongation Factor Beta 206.0 0 0 0 0 1.37432130302886 P32471 0.003130815224722028 8.054439544677733 2.5861706733703613 49.59059791516734 45.0 1.0 no 147 chrI_143002 455 essential YAL003W 462 + GCTCACCAATTTATCCCAAT H|156|D H|156|Y A|155|G A|155|V EFB1 Elongation Factor Beta 206.0 0 0 0 0 0.3368908826205791 P32471 0.1009601503610611 0.10833687335252762 0.1846660822629929 0.004974686540663242 1.8215999603271484 -1.4865800142288208 0.29649999737739563 0.5595399737358093 1.952538013458252 -1.5145859718322754 0.1496499925851822 0.9218819737434388 49.18412429266181 40.0 1.0 no 148 chrI_143802r 456 high_effect YAL002W 98 - ATGCCAGTTTTTCACTTAAT A|39|P A|39|T silent|CTG>CTC|L|38 silent|CTG>CTA|L|38 0 1 0 0 -0.6107854542742912 P39702 0.9573720097541808 0.9523990154266356 0.3120388686656952 0.3826694488525391 44.39300199594618 30.0 1.0 no 149 chrI_143866r 460 high_effect YAL002W 162 - ACTGCAGAAGCTACCCCTTT V|61|L V|61|M A|60|P A|60|T 0 0 0 0 -0.24257617089491995 P39702 0.9539830088615416 0.9587630033493042 0.9573720097541808 0.9523990154266356 0.4316853582859039 0.14830689132213593 0.2647773921489716 0.547296941280365 55.16262946408585 50.0 1.0 no 150 chrI_143897 462 high_effect YAL002W 190 + GCTCCGAATCCGTAGTCTCA S|65|C S|65|F silent|GGC>GGG|G|64 silent|GGC>GGT|G|64 0 0 0 0 0.0877964433359438 P39702 0.945252001285553 0.9294660091400146 0.16438059508800507 0.1697610765695572 55.98301843169536 55.00000000000001 1.0 no 151 chrI_143928 464 high_effect YAL002W 221 + AACACACGTATATTCCATCC T|75|R T|75|I H|76|D H|76|Y 0 0 0 0 1.1151368454085475 P39702 0.9476869702339172 0.9472420215606691 0.9473130106925964 0.9489949941635132 0.3426553308963776 0.1768050491809845 0.39339134097099293 0.11688468605279922 45.48562704628364 40.0 1.0 no 152 chrI_143929 465 high_effect YAL002W 222 + ACACACGTATATTCCATCCT H|76|D H|76|Y T|75|R T|75|I 0 0 0 0 -0.6335570204372067 P39702 0.9473130106925964 0.9489949941635132 0.9476869702339172 0.9472420215606691 0.39339134097099293 0.11688468605279922 0.3426553308963776 0.1768050491809845 48.74536475824562 40.0 1.0 no 153 chrI_144060 471 high_effect YAL002W 353 + CCTAGTGCCGACCTTATCTG L|119|V silent|CTA>TTA|L|119 0 0 0 0 -0.7334849602948416 P39702 0.9512209892272948 0.0 55.10878317615766 55.00000000000001 1.0 no 154 chrI_144118 475 high_effect YAL002W 411 + TCAATTGTCATATGTTCCGA S|138|* S|138|L 0 0 0 0 0.7636634577791922 P39702 0.9298099875450134 0.3950279951095581 44.55848940935618 35.0 1.0 no 155 chrI_144167r 477 high_effect YAL002W 463 - GTTCCAAATGCATATATTTC W|160|C W|160|* W|160|S W|160|* 0 0 0 0 -1.0533235201473303 P39702 0.8858469724655151 0.8858469724655151 0.0 0.0 40.48084933619936 30.0 1.0 no 156 chrI_144178 478 high_effect YAL002W 471 + TGCATTTGGAACTTGAACGT C|158|W silent|TGC>TGT|C|158 0 0 0 0 0.8166783918282634 P39702 0.9286419749259948 0.11137022078037262 43.27729744635877 40.0 1.0 no 157 chrI_144179 479 high_effect YAL002W 472 + GCATTTGGAACTTGAACGTA C|158|W silent|TGC>TGT|C|158 0 0 0 0 -0.5010818665388705 P39702 0.9286419749259948 0.11137022078037262 42.753829899703305 40.0 1.0 no 158 chrI_144259r 483 high_effect YAL002W 555 - TCATCGATGTGTAAGACTGC D|192|H D|192|N D|191|H D|191|N 0 0 0 0 -1.308737782477591 P39702 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.26579800248146057 1.0 0.17662595212459564 0.7709510326385498 45.09230296213865 45.0 1.0 no 159 chrI_144443r 485 high_effect YAL002W 739 - TGACCTTATTAATTTCTCCT R|252|S silent|AGG>AGA|R|252 R|252|T R|252|K 0 0 0 0 0.2273800506623052 P39702 0.9087679982185364 0.932735025882721 0.955805003643036 1.0 0.7353851199150085 0.8822808861732483 44.39748224978388 30.0 1.0 no 160 chrI_144440 486 high_effect YAL002W 733 + CTTCCAAGGAGAAATTAATA S|246|C S|246|F silent|TCC>TCG|S|246 silent|TCC>TCT|S|246 0 0 0 0 -0.4969196399598299 P39702 0.945252001285553 0.9294660091400146 0.020354218780994412 0.020497510209679604 36.133221411402076 30.0 1.0 no 161 chrI_144937 492 high_effect YAL002W 1230 + ACAAACTACTCATTTAAAAT T|411|R T|411|I N|412|K silent|AAC>AAT|N|412 0 0 0 0 1.1990401003465 P39702 0.9476869702339172 0.9472420215606691 0.9439849853515624 0.07627998292446136 0.043011721223592765 1.0 31.056322915699692 20.0 1.0 no 162 chrI_145257 498 high_effect YAL002W 1550 + TCCTTCTCTAGACGTCTTTT P|518|R P|518|L P|518|A P|518|S 0 0 0 0 -0.17815038543272774 P39702 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.5265827178955078 0.3233495652675629 0.7566354870796204 0.7298918366432191 50.6423186126554 40.0 1.0 no 163 chrI_145636r 503 high_effect YAL002W 1932 - TCAAATATAGTCGTTTCAGG D|651|H D|651|N 0 0 0 0 -0.4155303329142345 P39702 0.9486550092697144 0.956179976463318 0.03974853456020355 0.3636718094348908 39.91821430310364 35.0 1.0 no 164 chrI_146401r 517 high_effect YAL002W 2697 - TTGCCACATTCTAAACTTCC G|905|A G|905|D G|905|R G|905|S 0 0 0 0 0.07425127690222819 P39702 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.8328437209129333 0.6269652247428894 0.5450741648674011 0.7899675965309143 46.786518251568005 40.0 1.0 no 165 chrI_146447 518 high_effect YAL002W 2740 + ACTTTGATCTTCTTCTCTCA N|914|K silent|AAC>AAT|N|914 0 0 0 0 0.5360153440515343 P39702 0.9439849853515624 0.9394928216934204 47.5477075081472 35.0 1.0 no 166 chrI_146532r 520 high_effect YAL002W 2828 - TCTCCTCATTCTTTACTTCC E|949|Q E|949|K E|949|D silent|GAG>GAA|E|949 0 0 0 0 0.3081521755503861 P39702 0.956179976463318 0.9475290179252625 0.94931298494339 0.5767019987106323 0.924209713935852 0.6278437376022339 51.899858106877396 40.0 1.0 no 167 chrI_157540r 532 essential YAR007C 1057 + TTTCTATCTCTGTTGGCCTA S|354|C S|354|F RFA1 Replication Factor A 621.0 0 0 0 0 0.7246601228463583 P22336 0.945252001285553 0.9294660091400146 0.036135703325271606 0.03246791288256645 52.13509626358427 40.0 0.0 no 168 chrI_157565r 534 essential YAR007C 1032 + ATCACAATTGTTGACGACTC I|345|M silent|ATC>ATT|I|345 T|346|R T|346|I RFA1 Replication Factor A 621.0 0 0 0 0 -0.6971336653187002 P22336 0.9598389863967896 0.9476869702339172 0.9472420215606691 0.007213551085442305 0.02900549955666065 0.07838201522827147 42.17985250981985 40.0 0.0 no 169 chrI_157615r 535 essential YAR007C 982 + CACATTTTGAGCTAACTTCA H|329|D H|329|Y RFA1 Replication Factor A 621.0 0 0 0 0 0.8894858551960918 P22336 0.9473130106925964 0.9489949941635132 0.5779515504837036 0.709054172039032 42.55348615389846 35.0 0.0 no 170 chrI_157776 539 essential YAR007C 824 - TATCCAAATTCAGTTCATAA D|281|H D|281|N L|280|F silent|TTG>TTA|L|280 RFA1 Replication Factor A 621.0 0 0 0 0 -0.8615364207882181 P22336 0.9486550092697144 0.956179976463318 0.9587849974632264 0.01979074999690056 0.08539305627346039 0.4064280092716217 -0.70660001039505 -0.378600001335144 -0.4600000083446503 1.0218600034713743 37.5621910570577 25.0 0.0 no 171 chrI_157928r 544 essential YAR007C 669 + GTCAACTTCTTGGATACCTC silent|GTC>GTG|V|224 silent|GTC>GTT|V|224 N|225|K silent|AAC>AAT|N|225 RFA1 Replication Factor A 621.0 0 0 0 0 0.3382890021951405 P22336 0.9439849853515624 0.0553605742752552 -1.0793999433517456 48.414743343900106 45.0 0.0 no 172 chrI_158029r 548 essential YAR007C 568 + TGTCTCCATACCAAAACGTT S|191|C S|191|F P|192|A P|192|S RFA1 Replication Factor A 621.0 0 0 0 0 -1.0690988743183178 P22336 0.945252001285553 0.9294660091400146 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 0.31940001249313354 -0.4796000123023987 1.649799942970276 2.3968000411987305 45.548553975034 40.0 0.0 no 173 chrI_158198r 551 essential YAR007C 399 + GACGAAGATATAACTGACAG D|134|E silent|GAC>GAT|D|134 RFA1 Replication Factor A 621.0 0 0 0 0 -1.0312593573035422 P22336 0.9532920122146606 1.0 36.37551578072117 40.0 0.0 no 174 chrI_158256 554 essential YAR007C 344 - TATCCAAAAAAGTACTAGTT D|121|H D|121|N L|120|F silent|TTG>TTA|L|120 RFA1 Replication Factor A 621.0 0 0 0 0 -1.4827871626937112 P22336 0.9486550092697144 0.956179976463318 0.9587849974632264 0.013324399478733541 0.041130658239126205 0.08458750694990158 34.440180386477216 25.0 0.0 no 175 chrI_158283r 555 essential YAR007C 314 + GGTCCAGTCGCGTGCTGATA silent|GTC>GTG|V|106 silent|GTC>GTT|V|106 Q|107|E Q|107|* RFA1 Replication Factor A 621.0 0 0 0 0 -1.17524399053392 P22336 0.9590039849281312 1.0 58.78638198459107 60.0 0.0 no 176 chrI_158403r 562 essential YAR007C 194 + TGCATCCAAGTTCCAGTCAA A|66|G A|66|V S|67|C S|67|F RFA1 Replication Factor A 621.0 0 0 0 0 0.18302039246612395 P22336 0.9484469890594482 0.9504740238189696 0.945252001285553 0.9294660091400146 0.2870289087295532 1.0 0.04055717587471008 0.04826922714710236 51.198100739173576 45.0 0.0 no 177 chrI_158433 564 essential YAR007C 167 - TTCTCAACAGAGCCTTCATA R|62|T R|62|K L|61|F silent|TTG>TTA|L|61 RFA1 Replication Factor A 621.0 0 0 0 0 -1.6979229711285682 P22336 0.932735025882721 0.955805003643036 0.9587849974632264 0.539281964302063 1.0 0.30357083678245544 47.55966475333321 40.0 0.0 no 178 chrI_158527 567 essential YAR007C 73 - AACTTGATAAACGCCACCGG V|31|L V|31|I RFA1 Replication Factor A 621.0 0 0 0 0 -1.0552538239600808 P22336 0.9539830088615416 0.9574310183525084 0.1333092302083969 0.2962639033794403 45.97883089948078 50.0 0.0 no 179 chrI_158560r 569 essential YAR007C 37 + GCATCTTCACCAATAAGCAA S|13|R silent|AGC>AGT|S|13 I|14|M silent|ATC>ATT|I|14 RFA1 Replication Factor A 621.0 0 0 0 0 -1.1668275547302691 P22336 0.9417110085487366 0.9598389863967896 0.5747150182723999 0.03409893810749054 45.029040835620386 40.0 0.0 no 180 chrI_159505 576 essential YAR008W 539 + GCAGACCTATTTCTTATACA Q|181|E Q|181|* T|182|S T|182|I SEN34 Splicing ENdonuclease 275.0 0 0 0 0 0.5013285225948533 P39707 0.9590039849281312 0.9491789937019348 0.9472420215606691 1.0 0.4835738241672516 0.056765805929899216 45.26699742101607 35.0 1.0 no 181 chrI_159555r 579 essential YAR008W 592 - CCCACCAAAACGTCCACCTG G|204|R G|204|R G|204|A G|204|E SEN34 Splicing ENdonuclease 275.0 0 0 0 0 -1.4647135830361608 P39707 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.02595772780478001 0.02595772780478001 0.38512799143791204 0.03699588030576706 53.98130763092253 60.0 1.0 no 182 chrI_169411r 581 high_effect YAR015W 39 - ACTTTACCTCTGGCCACCAA V|20|L V|20|I G|18|A G|18|D ADE1 ADEnine requiring 306.0 0 0 0 0 0.20619215362349266 P27616 0.9539830088615416 0.9574310183525084 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 0.777180016040802 -0.2872399985790253 1.2780599594116209 -0.20166000723838806 -0.6265199780464172 -0.7149800062179565 55.16886471275279 50.0 1.0 no 183 chrI_169461 582 high_effect YAR015W 86 + TACGTTGCTGTTTGTTGCTA T|30|R T|30|M ADE1 ADEnine requiring 306.0 0 0 0 0 0.37824424773272297 P27616 0.9476869702339172 0.9502379894256592 0.544235348701477 0.11771584302186965 -0.13325999677181244 -1.8215800523757932 49.55360780958204 40.0 1.0 no 184 chrI_169720 592 high_effect YAR015W 345 + CCATTGGAAGTAATTGTCAG P|116|R P|116|L ADE1 ADEnine requiring 306.0 0 0 0 0 -1.1898533911304976 P27616 0.9432820081710817 0.9430609941482544 0.02117546647787094 0.004902913700789213 1.2261999845504759 1.2393399477005005 42.38016486375432 40.0 1.0 no 185 chrI_169845 594 high_effect YAR015W 470 + AATCTTCACCCCATCGACCA I|158|M silent|ATC>ATT|I|158 F|159|L silent|TTC>TTT|F|159 ADE1 ADEnine requiring 306.0 0 1 0 0 -0.23591623751094234 P27616 0.9598389863967896 0.9387490153312684 0.19298875331878665 0.015535619109869003 0.8125600218772888 2.488379955291748 54.436557765097284 50.0 1.0 no 186 chrI_172940 600 essential YAR019C 2176 - GATCTCCAGTCCACTTATGG E|731|D silent|GAG>GAA|E|731 E|731|Q E|731|K CDC15 Cell Division Cycle 974.0 0 0 0 0 0.0477766365777903 P27636 0.9565290212631226 0.9593430161476136 0.954060971736908 0.2532995343208313 0.0758085697889328 0.20085014402866366 52.800141384183576 50.0 0.0 no 187 chrI_173081 602 essential YAR019C 2035 - TGTCTTTGCGTCGTCGATAA K|684|N silent|AAG>AAA|K|684 CDC15 Cell Division Cycle 974.0 0 0 0 0 0.20629069788149207 P27636 0.9838269948959352 0.536361038684845 48.4465167078888 45.0 0.0 no 188 chrI_173405r 607 essential YAR019C 1708 + ATTCGGTACAGTCTCCATCA S|571|W S|571|L CDC15 Cell Division Cycle 974.0 0 1 0 0 -0.18633983459734196 P27636 0.8165209889411926 0.974943995475769 51.99644670437925 45.0 0.0 no 189 chrI_173829r 619 essential YAR019C 1284 + CCTCAGACTTTAATTGAATG Q|430|E Q|430|* P|429|R P|429|L CDC15 Cell Division Cycle 974.0 0 0 0 0 -2.0643768499626782 P27636 1.0025099515914917 0.9653800129890442 1.0257899761199951 0.4617779552936554 0.4433647394180298 0.6904280185699463 39.3236936571584 35.0 0.0 yes 190 chrI_173830 620 essential YAR019C 1286 - CACATTCAATTAAAGTCTGA C|435|S C|435|Y E|434|Q E|434|K CDC15 Cell Division Cycle 974.0 0 0 0 0 -0.057661219272186426 P27636 0.938202977180481 0.8312249779701233 1.0048899650573728 0.9880710244178772 0.2612602114677429 0.02459033951163292 1.0 0.26419928669929504 36.80328418856163 30.0 0.0 no 191 chrI_173936r 624 essential YAR019C 1177 + ATACCCAGCATAACCACTCT T|394|S T|394|I silent|ACC>ACG|T|394 silent|ACC>ACT|T|394 CDC15 Cell Division Cycle 974.0 0 0 0 0 0.4574452152633795 P27636 1.0364199876785278 1.048699975013733 0.4020383656024933 0.3960668742656708 51.38888057013594 45.0 0.0 no 192 chrI_173976r 625 essential YAR019C 1137 + AAACGATTAATAACTGCATT R|381|G R|381|* CDC15 Cell Division Cycle 974.0 0 0 0 0 0.3407868310822059 P27636 0.9557729959487916 0.3880994319915772 34.059719865817215 25.0 0.0 no 193 chrI_174185 634 essential YAR019C 931 - CGCTGCAAGACTGAATTTAG A|317|P A|317|T A|316|P A|316|T CDC15 Cell Division Cycle 974.0 0 0 0 0 -0.2854530597475193 P27636 1.0161499977111816 1.064869999885559 0.9489510059356691 0.9541059732437134 0.30521661043167114 1.0 0.27773067355155945 0.7337928414344788 42.724400416786644 45.0 0.0 no 194 chrI_174245r 635 essential YAR019C 868 + TTACCGACGCTGATTATCAT T|291|S T|291|I silent|ACC>ACG|T|291 silent|ACC>ACT|T|291 CDC15 Cell Division Cycle 974.0 0 0 0 0 0.4605319968031938 P27636 0.98574298620224 0.990090012550354 0.7169443964958191 0.19186839461326602 45.910576503975676 40.0 0.0 no 195 chrI_174274r 638 essential YAR019C 839 + CGACAAGCTCAACAAGTTCA D|281|E silent|GAC>GAT|D|281 CDC15 Cell Division Cycle 974.0 0 0 0 0 0.6260414350091278 P27636 1.0000699758529663 1.0 43.64398308070821 45.0 0.0 no 196 chrI_174397r 639 essential YAR019C 716 + CTCTTTCTCTGAGCCACTAA S|240|C S|240|F F|241|L silent|TTC>TTT|F|241 CDC15 Cell Division Cycle 974.0 0 0 0 0 -0.325063528948322 P27636 0.8388289809226991 0.9398040175437928 0.99692302942276 0.07929704338312149 0.20068703591823575 1.0 50.45434587586624 45.0 0.0 no 197 chrI_174530r 645 essential YAR019C 583 + CTTCTACGCTCAGCGACATT S|196|C S|196|F T|197|R T|197|M CDC15 Cell Division Cycle 974.0 0 0 0 0 -0.06661614859908832 P27636 0.9288560152053832 0.7774720191955566 0.8812969923019409 0.807852029800415 0.0 0.0 0.0 0.0 51.0208056694869 50.0 0.0 no 198 chrI_174639r 652 essential YAR019C 474 + ACTGTCAAACTTGCTGATTT T|159|S T|159|I silent|GTC>GTG|V|160 silent|GTC>GTT|V|160 CDC15 Cell Division Cycle 974.0 0 0 0 0 -0.31287213629585714 P27636 1.0190900564193726 1.0184099674224854 0.03215287998318672 0.4264914095401764 42.97740346272218 35.0 0.0 no 199 chrI_174685 653 essential YAR019C 431 - TAGCCGCCTTGATGTCCCTG A|150|P A|150|T silent|GCG>GCC|A|149 silent|GCG>GCA|A|149 CDC15 Cell Division Cycle 974.0 0 1 0 0 -0.12102232760168675 P27636 0.8199080228805542 0.8220030069351196 0.0 0.0 60.49334034399419 60.0 0.0 no 200 chrI_174786r 657 essential YAR019C 327 + CTCATTTCAAGGAGCTCTAC silent|CTC>CTG|L|110 silent|CTC>CTT|L|110 CDC15 Cell Division Cycle 974.0 0 0 0 0 -0.1169345306753938 P27636 46.64701786487621 45.0 0.0 no 201 chrI_174973r 660 essential YAR019C 140 + TGACCAAGTCGTGGCAATAA D|48|E silent|GAC>GAT|D|48 Q|49|E Q|49|* CDC15 Cell Division Cycle 974.0 0 0 0 0 -0.19951473070786965 P27636 0.9925739765167236 1.006160020828247 1.0 0.04324555769562721 45.51857628458811 45.0 0.0 no 202 chrI_175073 666 essential YAR019C 43 - TTTCTCAGATGCCCTCTGGA E|20|D silent|GAG>GAA|E|20 E|20|Q E|20|K CDC15 Cell Division Cycle 974.0 0 0 0 0 0.11285520306225234 P27636 0.9932379722595216 0.9934890270233154 0.9914820194244384 0.5409513115882874 0.5069244503974915 0.9454224705696106 56.09773133116596 50.0 0.0 no 203 chrI_175085r 667 essential YAR019C 28 + TCAACTTGACTCCCATCCAG silent|GTC>GTG|V|10 silent|GTC>GTT|V|10 N|11|K silent|AAC>AAT|N|11 CDC15 Cell Division Cycle 974.0 0 0 0 0 -0.3261232995142587 P27636 0.9723430275917052 0.02173822931945324 51.966490654061715 50.0 0.0 no 204 chrII_15123 669 essential YBL105C 2554 - ATCTTTCTTCAGAACTTTTA D|858|H D|858|N K|856|N silent|AAG>AAA|K|856 PKC1 Protein Kinase C 1151.0 0 0 0 0 0.2600499339453538 P24583 0.9486550092697144 0.956179976463318 0.9355990290641784 0.006561442743986845 0.014350739307701588 0.0 39.8813644465917 25.0 0.0 no 205 chrII_15412 672 essential YBL105C 2265 - TCACTATTCATATCGCGGAA S|761|T S|761|N E|762|Q E|762|K PKC1 Protein Kinase C 1151.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.17893286745367806 P24583 0.9512869715690612 0.9536849856376648 0.956179976463318 0.9475290179252625 0.5754370093345642 0.4962871074676514 0.6644308567047119 0.8770472407341003 44.41984004752936 40.0 0.0 no 206 chrII_15527 674 essential YBL105C 2150 - GATCAACTTCTAGATCCTCT D|723|H D|723|N V|722|L V|722|I PKC1 Protein Kinase C 1151.0 0 0 0 0 0.993150808498819 P24583 0.9486550092697144 0.956179976463318 0.9539830088615416 0.9574310183525084 0.11705311387777327 0.5353509187698364 0.3761237859725952 0.2324410676956177 46.79751282318625 40.0 0.0 no 207 chrII_15754r 677 essential YBL105C 1920 + GCCTATTTAAATTTTACAGA silent|GCC>GCG|A|641 silent|GCC>GCT|A|641 A|641|G A|641|V PKC1 Protein Kinase C 1151.0 0 0 0 1 0.9870120916768212 P24583 0.9484469890594482 0.9504740238189696 0.3623761832714081 0.2991500496864319 38.37253003623772 25.0 0.0 no 208 chrII_15717 678 essential YBL105C 1960 - TTTCTCTGGTGATGAAAATT E|659|D silent|GAG>GAA|E|659 E|659|Q E|659|K PKC1 Protein Kinase C 1151.0 0 1 0 0 -1.49498943723872 P24583 0.94931298494339 0.956179976463318 0.9475290179252625 0.5601852536201477 0.5270305871963501 0.7930551767349243 38.4652056071663 30.0 0.0 no 209 chrII_16092 690 essential YBL105C 1585 - CATCGACATGCCACAGAAAT silent|TCG>TCC|S|534 silent|TCG>TCA|S|534 M|533|I M|533|I PKC1 Protein Kinase C 1151.0 0 0 0 0 0.3878675264609453 P24583 0.9553959965705872 0.9553959965705872 0.07698998600244522 0.07698998600244522 44.504867216960285 45.0 0.0 no 210 chrII_16093 691 essential YBL105C 1584 - ATCGACATGCCACAGAAATC silent|TCG>TCC|S|534 silent|TCG>TCA|S|534 M|533|I M|533|I PKC1 Protein Kinase C 1151.0 0 0 0 0 -0.6821597369215953 P24583 0.9553959965705872 0.9553959965705872 0.07698998600244522 0.07698998600244522 44.20056342832317 45.0 0.0 no 211 chrII_16118r 692 essential YBL105C 1556 + TCATGCTCAATGTGCTCATT H|520|D H|520|Y A|521|G A|521|V PKC1 Protein Kinase C 1151.0 0 0 0 0 -0.4289150305547392 P24583 0.9473130106925964 0.9489949941635132 0.9484469890594482 0.9504740238189696 0.0 0.0 0.07635307312011719 0.19214317202568051 48.44365260302697 40.0 0.0 no 212 chrII_16208 694 essential YBL105C 1469 - GACAGCACCATTTAGTACCA C|496|S C|496|Y C|495|S C|495|Y PKC1 Protein Kinase C 1151.0 0 0 0 0 0.4715661544957126 P24583 0.9421560168266296 0.9290120005607604 0.9421560168266296 0.9290120005607604 0.0 0.0 0.0 0.0 50.42267202665379 45.0 0.0 no 213 chrII_16215r 695 essential YBL105C 1459 + CTTCAAACCGTGGTACTAAA S|488|* S|488|L PKC1 Protein Kinase C 1151.0 0 0 0 0 -0.3803845774661285 P24583 0.9298099875450134 0.00911245122551918 41.90363424772761 40.0 0.0 no 214 chrII_16283r 699 essential YBL105C 1391 + AACTTCTACTGATACGGATC T|465|S T|465|I S|466|C S|466|F PKC1 Protein Kinase C 1151.0 0 1 0 0 0.3825132137286619 P24583 0.9491789937019348 0.9472420215606691 0.945252001285553 0.9294660091400146 1.0 0.007040858268737794 0.059583630412817 0.03637920692563057 41.712028396570304 40.0 0.0 no 215 chrII_16558r 702 essential YBL105C 1116 + GGGCAGATTTTGTTAACACT Q|374|E Q|374|* PKC1 Protein Kinase C 1151.0 0 0 0 0 0.2229804545725307 P24583 0.9590039849281312 0.03545694053173065 45.78323677524219 40.0 0.0 no 216 chrII_16706r 706 essential YBL105C 968 + TTCTTCTCTCGCTAGCGAAG S|324|C S|324|F S|325|C S|325|F PKC1 Protein Kinase C 1151.0 0 0 0 0 0.2889741866641864 P24583 0.945252001285553 0.9294660091400146 0.945252001285553 0.9294660091400146 0.05970833823084831 0.0550001747906208 0.07811154425144196 0.14276011288166046 50.043185912190275 50.0 0.0 no 217 chrII_16729r 707 essential YBL105C 945 + AACGCTTCAAACATTAATGG N|316|K silent|AAC>AAT|N|316 A|317|G A|317|V PKC1 Protein Kinase C 1151.0 0 0 0 0 -0.588419979063022 P24583 0.9439849853515624 0.9484469890594482 0.9504740238189696 0.1896585524082184 0.0 0.0 37.56612179773458 35.0 0.0 no 218 chrII_16794 709 essential YBL105C 883 - ACGAATTTCTTCAGCGATAT R|301|P R|301|H PKC1 Protein Kinase C 1151.0 0 0 0 0 0.8954318251644022 P24583 0.9099509716033936 0.9570810198783876 0.0 0.0 42.18444518010483 35.0 0.0 no 219 chrII_16996 712 essential YBL105C 681 - TCTGGCTTCCTGGCAAACAT E|234|Q E|234|K K|232|N silent|AAG>AAA|K|232 PKC1 Protein Kinase C 1151.0 0 0 0 0 -0.7927511047074213 P24583 0.956179976463318 0.9475290179252625 0.9355990290641784 0.018496844917535785 0.01436152495443821 0.2341485470533371 52.6832939493819 50.0 0.0 no 220 chrII_17187 716 essential YBL105C 490 - AAGCATTTGAATCCTGTATT M|169|I M|169|I PKC1 Protein Kinase C 1151.0 0 1 0 0 0.3402414916049198 P24583 0.9553959965705872 0.9553959965705872 0.021394819021224976 0.021394819021224976 41.83067485125929 30.0 0.0 no 221 chrII_17254r 719 essential YBL105C 420 + ACTAAATTGTATCAAATTGA T|141|S T|141|I PKC1 Protein Kinase C 1151.0 0 1 0 0 -0.1618644126972036 P24583 0.9491789937019348 0.9472420215606691 0.1637144237756729 0.48182797431945795 31.69173414756005 20.0 0.0 no 222 chrII_40965r 727 essential YBL097W 137 - ATGCGAAATTCCAACTATTT A|52|P A|52|T 0 0 0 0 -0.3996174639448508 P38170 0.9573720097541808 0.9523990154266356 0.018699906766414642 0.013268131762742994 39.86925618874301 30.0 1.0 no 223 chrII_41260r 734 essential YBL097W 432 - ACATCAGGATCATTAGATAT V|151|L V|151|M D|150|H D|150|N 0 0 0 0 0.03184996520372632 P38170 0.9539830088615416 0.9587630033493042 0.9486550092697144 0.956179976463318 0.3793402910232544 0.13657450675964355 0.06651719659566879 0.2997886538505554 39.47432006435122 30.0 1.0 no 224 chrII_41386r 735 essential YBL097W 558 - ACCAAGGCCTTTTTGAATAA L|192|F silent|TTG>TTA|L|192 V|193|L V|193|I 0 0 0 0 -0.5416590397633503 P38170 0.9587849974632264 0.9539830088615416 0.9574310183525084 0.0 0.14035940170288086 0.3152710497379303 43.792164373286255 35.0 1.0 no 225 chrII_41401 736 essential YBL097W 570 + GCCTTGGTTGATTTCGATGA silent|GCC>GCG|A|191 silent|GCC>GCT|A|191 A|191|G A|191|V 0 0 0 0 0.16606188166282887 P38170 0.9484469890594482 0.9504740238189696 0.03176145255565643 0.025389069691300392 50.284552160346315 45.0 1.0 no 226 chrII_41847r 739 essential YBL097W 1019 - TATCATCTTCTGCATTATCT D|346|H D|346|N D|345|H D|345|N 0 0 0 0 -0.042972931160006465 P38170 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.10179810971021652 0.4046509563922882 0.12376546114683153 0.3496510088443756 44.26675957537975 30.0 1.0 no 227 chrII_42135 743 essential YBL097W 1304 + TACTACTGACAAAAACACAA T|436|S T|436|I T|437|S T|437|I 1 Series([], Name: modification, dtype: object) 0 0 0 1.112568155152967 P38170 0.9491789937019348 0.9472420215606691 0.9491789937019348 0.9472420215606691 0.6936953067779541 0.17713738977909088 0.7336018681526184 0.18890981376171112 33.10401119664397 30.0 1.0 no 228 chrII_42150 744 essential YBL097W 1319 + CACAACGGACGACAAATCGA T|441|R T|441|I T|442|R T|442|M 0 1 0 0 0.4515038058785271 P38170 0.9476869702339172 0.9472420215606691 0.9476869702339172 0.9502379894256592 0.5211356282234192 0.1883301287889481 0.5237343907356262 0.10816418379545213 41.6745115684098 50.0 1.0 no 229 chrII_42306 745 essential YBL097W 1475 + CGACACACATTATTTACTGC D|493|E silent|GAC>GAT|D|493 T|494|R T|494|I 0 0 0 0 -1.0946661347997442 P38170 0.9532920122146606 0.9476869702339172 0.9472420215606691 1.0 0.12895354628562927 0.04952341318130493 42.60685286047283 40.0 1.0 no 230 chrII_42286r 747 essential YBL097W 1458 - TCGTTCTTTCTGTTCTTAAT D|493|H D|493|N K|491|N silent|AAG>AAA|K|491 0 0 0 0 0.6793960860292134 P38170 0.9486550092697144 0.956179976463318 0.9355990290641784 0.06168117746710777 0.17706429958343506 0.4877583682537079 44.0839274429037 30.0 1.0 no 231 chrII_42400 751 essential YBL097W 1569 + AGTCATAGGAAGCATACCAG H|525|D H|525|Y 0 0 0 0 -0.4660671075905243 P38170 0.9473130106925964 0.9489949941635132 0.666923463344574 0.779617190361023 45.85925789309226 45.0 1.0 no 232 chrII_44514r 763 high_effect YBL093C 382 + TTCAGCCTCCAAATTTCGAT Q|129|E Q|129|* P|130|A P|130|S ROX3 Regulation by OXygen 220.0 0 0 0 0 0.023582571367549487 P25046 0.9590039849281312 0.9562489986419678 0.9498909711837769 1.0 0.4560104608535767 0.08173692971467973 47.99071173233421 40.0 0.0 no 233 chrII_44662 766 high_effect YBL093C 237 - CCTTTACCATTTTCTCTGGT G|86|R G|86|S G|84|A G|84|D ROX3 Regulation by OXygen 220.0 0 0 0 0 -0.2668045803327956 P25046 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.4798032939434052 0.618870735168457 0.7502766251564026 0.6146730780601501 52.02529578591134 40.0 0.0 no 234 chrII_45990r 775 essential YBL092W 15 - TTCTTGACAATCTTTGGGTG K|11|N silent|AAG>AAA|K|11 RPL32 Ribosomal Protein of the Large subunit 130.0 0 0 0 0 0.04835107490983104 P38061 0.0046319132670760155 0.3747999966144562 44.62296494654811 40.0 1.0 no 235 chrII_46046r 776 essential YBL092W 71 - TTTCAGCAACTCTGTGGTAA E|30|Q E|30|K A|29|P A|29|T RPL32 Ribosomal Protein of the Large subunit 130.0 0 0 0 0 0.6131386109983628 P38061 0.562755286693573 0.8251219987869263 0.12888875603675842 0.1381225734949112 0.4965400099754334 0.6247000098228455 -0.8769999742507935 1.0470999479293823 46.030633789450405 40.0 1.0 no 236 chrII_46196 779 essential YBL092W 218 + TTTCTTAGTCGCTAACGTTA F|74|L silent|TTC>TTT|F|74 RPL32 Ribosomal Protein of the Large subunit 130.0 0 1 0 0 0.9563219073893334 P38061 0.034157350659370415 0.30498000979423523 0.5253999829292297 44.36387571112709 35.0 1.0 no 237 chrII_81831r 784 essential YBL076C 2408 + CCATTTCTTATCTTACCCAG H|804|D H|804|Y F|805|L silent|TTC>TTT|F|805 ILS1 IsoLeucine-tRNA Synthetase 1072.0 0 0 0 0 0.6935651289084237 P09436 0.9473130106925964 0.9489949941635132 0.9387490153312684 0.004129381850361824 0.0019905774388462305 0.04557853937149048 49.40874420881079 40.0 0.0 no 238 chrII_81954r 788 essential YBL076C 2285 + ATTCACATTTGTCCGTGCCA F|763|L silent|TTC>TTT|F|763 T|764|R T|764|I ILS1 IsoLeucine-tRNA Synthetase 1072.0 0 0 0 0 -0.9032066832302909 P09436 0.9387490153312684 0.9476869702339172 0.9472420215606691 1.0 0.10712239891290663 0.0240256879478693 53.878793478307394 45.0 0.0 no 239 chrII_82063r 791 essential YBL076C 2176 + TCATTGATGAATTGACAAAC F|726|L silent|TTC>TTT|F|726 ILS1 IsoLeucine-tRNA Synthetase 1072.0 0 0 0 0 1.4020069781456874 P09436 0.9387490153312684 0.4069257080554962 34.060850262409986 30.0 0.0 no 240 chrII_82288r 792 essential YBL076C 1951 + TTTCAAAGGTCTTACTACCA S|652|* S|652|L ILS1 IsoLeucine-tRNA Synthetase 1072.0 0 0 0 0 -0.7844014851579642 P09436 0.9298099875450134 0.013842988759279251 43.80960733956295 35.0 0.0 no 241 chrII_82399 793 essential YBL076C 1843 - ACCATATTTGTTCAGAACAA G|621|R G|621|S G|621|A G|621|D ILS1 IsoLeucine-tRNA Synthetase 1072.0 0 1 0 0 -1.1200380777320371 P09436 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.001168234972283244 0.06025048345327377 0.012192984111607076 0.00255944998934865 40.00160611276982 30.0 0.0 no 242 chrII_82400r 795 essential YBL076C 1839 + TCCATTGTTCTGAACAAATA silent|TCC>TCG|S|614 silent|TCC>TCT|S|614 S|614|C S|614|F ILS1 IsoLeucine-tRNA Synthetase 1072.0 0 0 0 1 -0.2182325346534049 P09436 0.945252001285553 0.9294660091400146 0.09075412899255753 0.1433473527431488 39.30037877585562 30.0 0.0 no 243 chrII_82517r 798 essential YBL076C 1722 + GTCTTAGGTACCCATCTATT silent|GTC>GTG|V|575 silent|GTC>GTT|V|575 ILS1 IsoLeucine-tRNA Synthetase 1072.0 0 0 0 0 -0.005496823435288012 P09436 51.03531351350938 40.0 0.0 no 244 chrII_82532r 799 essential YBL076C 1707 + TTCTACACGTTAGCTGTCTT F|570|L silent|TTC>TTT|F|570 Y|571|* silent|TAC>TAT|Y|571 ILS1 IsoLeucine-tRNA Synthetase 1072.0 0 0 0 0 1.1596536034852991 P09436 0.9387490153312684 0.019420772790908813 48.78476867612136 40.0 0.0 no 245 chrII_82577r 800 essential YBL076C 1662 + CCAGCTAATTTCATCTCTGA P|555|R P|555|L A|556|G A|556|V ILS1 IsoLeucine-tRNA Synthetase 1072.0 0 0 0 0 0.25274569701378513 P09436 0.9432820081710817 0.9430609941482544 0.9484469890594482 0.9504740238189696 0.0 0.0 0.2714128792285919 0.0037276069633662705 47.52209884864567 40.0 0.0 no 246 chrII_82709 801 essential YBL076C 1533 - TCACCCTTACCTTGCTTGGA G|517|A G|517|D D|518|H D|518|N ILS1 IsoLeucine-tRNA Synthetase 1072.0 0 0 0 0 -0.3867438374069961 P09436 0.9499930143356324 0.9446240067481996 0.9486550092697144 0.956179976463318 0.09068138152360916 0.08609888702630998 0.16210146248340607 0.510197639465332 56.696033269816205 50.0 0.0 no 247 chrII_82841 803 essential YBL076C 1401 - TCTGAAACCCATAAAGGAAT D|474|H D|474|N ILS1 IsoLeucine-tRNA Synthetase 1072.0 0 0 0 0 -0.5168243100774821 P09436 0.9486550092697144 0.956179976463318 0.0046532577835023394 0.008063403889536858 38.95928839711922 35.0 0.0 no 248 chrII_82870r 804 essential YBL076C 1369 + ACGTTTCCAGAAATAGATAT N|457|K silent|AAC>AAT|N|457 S|459|C S|459|F ILS1 IsoLeucine-tRNA Synthetase 1072.0 0 0 0 0 0.2450066483893485 P09436 0.9439849853515624 0.945252001285553 0.9294660091400146 0.12992113828659058 0.0014408719725906847 0.0005505750305019318 38.77560091868645 30.0 0.0 no 249 chrII_82888 806 essential YBL076C 1354 - AACGTTCCAGTCACGGGCAT V|458|L V|458|I W|456|C W|456|* ILS1 IsoLeucine-tRNA Synthetase 1072.0 0 0 0 0 -0.7007694808828271 P09436 0.9539830088615416 0.9574310183525084 0.8858469724655151 0.0199265331029892 1.0 0.0 54.171075248448524 55.00000000000001 0.0 no 250 chrII_82928 808 essential YBL076C 1314 - CTCTTTTCCTTGATGGTGTT K|444|N silent|AAG>AAA|K|444 ILS1 IsoLeucine-tRNA Synthetase 1072.0 0 0 0 0 0.33791580072463245 P09436 0.9355990290641784 0.0955127254128456 50.8738746955334 40.0 0.0 no 251 chrII_82953r 809 essential YBL076C 1286 + TTCTGTGATGAAATCTCACT S|430|C S|430|F ILS1 IsoLeucine-tRNA Synthetase 1072.0 0 0 0 0 0.5892988132264961 P09436 0.945252001285553 0.9294660091400146 0.19751560688018802 0.007340701296925546 41.48072826667168 35.0 0.0 no 252 chrII_82977r 811 essential YBL076C 1262 + AAACATTGTCCCTCAAATGT N|422|K silent|AAC>AAT|N|422 ILS1 IsoLeucine-tRNA Synthetase 1072.0 0 1 0 0 0.23437539868846946 P09436 0.9439849853515624 0.8211916089057922 43.080348706877146 35.0 0.0 no 253 chrII_83552 823 essential YBL076C 690 - ACACATAACGACAAATTGGA C|236|S C|236|Y V|237|L V|237|I ILS1 IsoLeucine-tRNA Synthetase 1072.0 0 0 0 0 0.5573598446783841 P09436 0.9421560168266296 0.9290120005607604 0.9539830088615416 0.9574310183525084 0.08161497861146927 0.00109211599919945 0.01741581410169601 0.05377630144357681 37.126568048680326 35.0 0.0 no 254 chrII_83639r 827 essential YBL076C 600 + AACGACCCAGCTGTGACCAT N|201|K silent|AAC>AAT|N|201 D|202|E silent|GAC>GAT|D|202 ILS1 IsoLeucine-tRNA Synthetase 1072.0 0 0 0 0 0.033012958068743936 P09436 0.9439849853515624 0.9532920122146606 0.9307818412780762 0.004481133073568344 54.00885911697589 55.00000000000001 0.0 no 255 chrII_83756r 828 essential YBL076C 483 + TTCAAGCAACTTCATGAAAA F|162|L silent|TTC>TTT|F|162 Q|164|E Q|164|* ILS1 IsoLeucine-tRNA Synthetase 1072.0 0 0 0 0 0.3633659815847177 P09436 0.9387490153312684 0.9590039849281312 0.005546705331653357 0.2186494767665863 35.98426767385501 30.0 0.0 no 256 chrII_84038 836 essential YBL076C 204 - CCTGTCATGGTAGCGTATCT G|75|R G|75|S M|73|I M|73|I ILS1 IsoLeucine-tRNA Synthetase 1072.0 0 0 0 0 -0.8067685375184426 P09436 0.941340982913971 0.951104998588562 0.9553959965705872 0.9553959965705872 0.001570333493873477 0.00539438147097826 0.14250926673412326 0.14250926673412326 54.20942431715963 50.0 0.0 no 257 chrII_84222r 842 essential YBL076C 17 + ACACTTCTCATTTCCAAAGG H|7|Q silent|CAC>CAT|H|7 H|7|D H|7|Y ILS1 IsoLeucine-tRNA Synthetase 1072.0 0 1 0 0 0.3211835051900876 P09436 0.9588389992713928 0.9473130106925964 0.9489949941635132 0.3848686218261719 0.4246344268321991 0.015812402591109276 44.68411172985799 40.0 0.0 no 258 chrII_87061r 844 essential YBL074C 706 + ACTACGGGTCGAGTTTGCAA N|236|K silent|AAC>AAT|N|236 Y|237|* silent|TAC>TAT|Y|237 AAR2 A1-Alpha2 Repression 355.0 0 0 0 0 -1.9927672993475325 P32357 0.96738600730896 0.021193567663431168 6.147659778594972 49.7478878061437 50.0 0.0 no 259 chrII_87390 850 essential YBL074C 380 - CATCTTTCCTTACTATCTTT D|133|H D|133|N AAR2 A1-Alpha2 Repression 355.0 0 0 0 0 -0.8394745071639093 P32357 0.9728149771690368 0.9840490221977234 0.1393987387418747 0.5415539145469666 0.5117200016975403 0.31384000182151794 45.28382673409863 30.0 0.0 no 260 chrII_87537r 854 essential YBL074C 230 + TTACAAAATGATGGAAGAAA Y|78|* silent|TAC>TAT|Y|78 AAR2 A1-Alpha2 Repression 355.0 0 0 0 0 0.228493921689377 P32357 29.86754987406664 25.0 0.0 no 261 chrII_87540 855 essential YBL074C 230 - TTTCTTCCATCATTTTGTAA E|83|Q E|83|K E|82|Q E|82|K AAR2 A1-Alpha2 Repression 355.0 0 0 0 0 0.5050970667867177 P32357 0.9857460260391236 0.9736970067024232 0.9840490221977234 0.972000002861023 0.0674082562327385 0.060683295130729675 0.5748708248138428 0.9397375583648682 0.239779993891716 0.1929599940776825 -0.2432200014591217 -1.611840009689331 42.3898809253468 25.0 0.0 no 262 chrII_87613r 858 essential YBL074C 154 + CCAGCATGAGGTATGGCTAC silent|TCC>TCG|S|52 silent|TCC>TCT|S|52 S|53|R silent|AGC>AGT|S|53 AAR2 A1-Alpha2 Repression 355.0 0 0 0 0 -0.8639403215923477 P32357 0.9573389887809752 0.10536762326955797 0.16502000391483307 -0.17657999694347382 52.99520156519839 55.00000000000001 0.0 no 263 chrII_87687r 861 essential YBL074C 80 + TCAGCCATTTCACGGAATCA Q|28|E Q|28|* P|29|A P|29|S AAR2 A1-Alpha2 Repression 355.0 0 0 0 0 -0.4383970771864519 P32357 0.987945020198822 0.9201790094375609 0.9116989970207214 0.299668550491333 0.06827298551797867 0.042990528047084815 0.08290000259876251 0.377020001411438 2.3470399379730225 49.10312612831922 45.0 0.0 no 264 chrII_87714r 862 essential YBL074C 53 + TCAGTATTCCTTTAATGTCA Q|19|E Q|19|* AAR2 A1-Alpha2 Repression 355.0 0 0 0 0 0.5735380238538995 P32357 0.986248016357422 0.8424949049949646 0.5316799879074097 43.66623977971933 30.0 0.0 no 265 chrII_111506 865 high_effect YBL058W 69 + GTTCAATATCTCTCTGAATT Q|25|E Q|25|* SHP1 Suppressor of High-copy PP1 423.0 0 0 0 0 0.6541868497177766 P34223 0.9590039849281312 1.0 40.38716230091643 30.0 1.0 no 266 chrII_111577r 867 high_effect YBL058W 143 - CTTCCTCTCTTCTATCCTTT E|54|Q E|54|K E|53|D silent|GAG>GAA|E|53 SHP1 Suppressor of High-copy PP1 423.0 0 0 0 0 -0.0889564008482925 P34223 0.956179976463318 0.9475290179252625 0.94931298494339 53.983490267428074 40.0 1.0 no 267 chrII_111755 877 high_effect YBL058W 318 + ACCTCTCCTGAACCAACCAA silent|ACC>ACG|T|107 silent|ACC>ACT|T|107 T|107|S T|107|I SHP1 Suppressor of High-copy PP1 423.0 0 0 1 Series([], Name: modification, dtype: object) 0 -1.679026813677314 P34223 0.9491789937019348 0.9472420215606691 0.9337788224220276 0.10380925983190536 51.816396108519534 50.0 1.0 no 268 chrII_112029r 887 high_effect YBL058W 595 - ACCTCTTCCAGTAAACCTAT G|205|R G|205|S G|205|A G|205|D SHP1 Suppressor of High-copy PP1 423.0 0 0 0 0 0.7551151230634825 P34223 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 48.95883108745159 40.0 1.0 no 269 chrII_112015r 888 high_effect YBL058W 581 - ACCTATTGGCACCCATTTCA R|200|T R|200|K R|200|S silent|AGG>AGA|R|200 SHP1 Suppressor of High-copy PP1 423.0 0 0 0 0 -0.06986382821274742 P34223 0.932735025882721 0.955805003643036 0.9087679982185364 0.3729316890239716 1.0 0.41610801219940186 54.3413780942264 45.0 1.0 no 270 chrII_125133r 904 essential YBL050W 11 - CTCTTTTCAATAACTCTACA R|10|T R|10|K SEC17 SECretory 292.0 0 0 0 0 -1.7702175572239116 P32602 0.9407349824905396 0.9577590227127076 0.08049976080656053 1.0 0.34279999136924744 -0.4077999889850617 39.557794491505945 30.0 1.0 no 271 chrII_125321 905 essential YBL050W 80 + TTCTGATTCATACAAGTTTG S|28|C S|28|F SEC17 SECretory 292.0 0 0 0 0 -0.8832846550895229 P32602 0.9478139877319336 0.9257050156593324 0.05743241310119629 0.05185521394014359 -0.39079999923706055 -0.66839998960495 0.16315999627113342 -0.20574000477790835 38.63566070155588 30.0 1.0 no 272 chrII_125374r 907 essential YBL050W 136 - CTCTTTTCTTAGACGGTAAA E|52|Q E|52|K SEC17 SECretory 292.0 0 0 0 0 -1.3186765788771346 P32602 0.9594100117683412 0.9491919875144958 0.6306448578834534 0.8961607217788696 -0.5573999881744385 -0.7483999729156494 41.434128112152905 35.0 1.0 no 273 chrII_125426 909 essential YBL050W 185 + AGCTGCTGACTATCAGAAAA A|63|G A|63|V A|64|G A|64|V SEC17 SECretory 292.0 0 0 0 0 0.6774825443367518 P32602 0.9542440176010132 0.95346999168396 0.9672009944915771 0.9664270281791688 0.019042490050196648 0.14190766215324402 0.02460042014718056 0.007838182151317595 1.7189999818801882 4.8917999267578125 1.2719999551773071 4.9892001152038565 1.658519983291626 4.248879909515382 1.4945000410079956 5.9024200439453125 42.20385047687154 40.0 1.0 no 274 chrII_125476r 912 essential YBL050W 238 - GCATTTATAAGCCTCTACGT C|86|S C|86|Y SEC17 SECretory 292.0 0 0 0 0 -0.7571860709762752 P32602 0.9408739805221558 0.9166489839553832 0.5237458944320679 0.011260506696999071 1.5900000333786009 3.6858000755310063 0.6356599926948547 3.0533599853515625 47.86594787558585 40.0 1.0 no 275 chrII_125527r 913 essential YBL050W 289 - AGCATTTTCTAATGAATCCA A|103|P A|103|T SEC17 SECretory 292.0 0 0 0 0 -3.62811732227038 P32602 0.9770879745483398 0.9687960147857666 0.01286088302731514 0.00896896794438362 6.1753997802734375 1.454800009727478 5.893020153045653 0.9520999789237976 41.63346375826347 30.0 1.0 yes 276 chrII_125551 914 essential YBL050W 310 + TTCAAATTTTTACTCATAGG Q|105|E Q|105|* SEC17 SECretory 292.0 0 0 0 0 0.13656814854629226 P32602 0.9537799954414368 1.0 -0.0003999999898951501 35.7024617176844 25.0 1.0 no 277 chrII_125579r 916 essential YBL050W 341 - ACTTGAAATTAGCACCTCTC K|120|N silent|AAG>AAA|K|120 SEC17 SECretory 292.0 0 0 0 0 -3.0072128296173988 P32602 0.9444509744644164 0.032229285687208176 1.749400019645691 44.54016131389756 40.0 1.0 yes 278 chrII_125589 917 essential YBL050W 348 + GCTAATTTCAAGTTTGAGCT A|117|G A|117|V SEC17 SECretory 292.0 0 0 0 0 0.6424574596978505 P32602 0.9109870195388794 0.9102140069007874 0.0 0.0 1.378000020980835 5.781599998474121 1.7717000246047974 4.762499809265137 43.726947606919744 35.0 1.0 no 279 chrII_125891 919 essential YBL050W 650 + TGCTGCAAGAACTTTACAAG A|218|G A|218|V A|219|G A|219|V SEC17 SECretory 292.0 0 0 0 0 0.3117969047975613 P32602 0.9272080063819884 0.928013026714325 0.9410769939422609 0.9418820142745972 0.004785491153597832 0.771602213382721 0.4262559115886688 0.28546050190925604 1.7970000505447388 1.4210000038146973 1.2070000171661377 1.1782000064849854 2.0573999881744385 0.06428000330924988 1.31850004196167 0.478879988193512 40.602178435901976 40.0 1.0 no 280 chrII_141298 920 essential YBL041W 51 + GAACATCAATTCAATCCTTA H|19|D H|19|Y Q|20|E Q|20|* PRE7 PRoteinase yscE 241.0 0 0 0 0 0.19621839049945214 P23724 0.21920807659626007 0.9329797625541688 0.714248776435852 -0.22322000563144684 -0.2567200064659119 39.101717287805 30.0 1.0 no 281 chrII_141258 922 essential YBL041W 11 + TGCATCAGAATACTCTTCGG A|5|G A|5|V S|6|* S|6|L PRE7 PRoteinase yscE 241.0 0 1 0 0 -1.9856108383930715 P23724 0.4188891351222992 0.3501957952976227 0.12196638435125352 45.60563642409375 45.0 1.0 no 282 chrII_141339r 924 essential YBL041W 95 - AATCTTCACCTGCAATGCCC D|38|H D|38|N E|37|Q E|37|K PRE7 PRoteinase yscE 241.0 0 0 0 0 -1.5597206577556997 P23724 0.008317943662405014 0.06367845088243483 0.20602448284626007 0.5456805825233461 53.42709301405392 50.0 1.0 no 283 chrII_141424r 926 essential YBL041W 180 - TCACCACAATCAAAAACCTT G|66|A G|66|D D|67|H D|67|N PRE7 PRoteinase yscE 241.0 0 0 0 0 -0.6290713289238535 P23724 0.27622994780540466 0.3242855370044708 0.015015685930848122 0.15407247841358185 0.4058400094509125 -0.1967799961566925 40.51902197169108 35.0 1.0 no 284 chrII_141577 929 essential YBL041W 330 + AACATTCAACATCTTCTGTA N|111|K silent|AAC>AAT|N|111 Q|113|E Q|113|* PRE7 PRoteinase yscE 241.0 0 0 0 0 -0.09085011219946458 P23724 0.08094880729913713 0.06511502712965013 -0.5653200149536133 0.7916200160980225 40.03062946033344 30.0 1.0 no 285 chrII_141578 931 essential YBL041W 331 + ACATTCAACATCTTCTGTAC N|111|K silent|AAC>AAT|N|111 Q|113|E Q|113|* PRE7 PRoteinase yscE 241.0 0 0 0 0 0.06347685068702813 P23724 0.08094880729913713 0.06511502712965013 -0.5653200149536133 0.7916200160980225 41.946352419504365 35.0 1.0 no 286 chrII_141682r 936 essential YBL041W 438 - TCTCTTTCGTAGGAGCCAAC R|152|T R|152|K E|153|Q E|153|K PRE7 PRoteinase yscE 241.0 0 0 0 0 -1.5650103802061248 P23724 0.0480026938021183 0.0826382264494896 0.1964509338140488 0.2648172378540039 51.17127181980016 50.0 1.0 no 287 chrII_141732 938 essential YBL041W 485 + ATCATTGATCATGCCATTTT S|163|* S|163|L PRE7 PRoteinase yscE 241.0 0 0 0 0 0.2240144935769378 P23724 0.029539821669459343 44.84864407719402 30.0 1.0 no 288 chrII_146313r 941 high_effect YBL038W 129 - TTCTGTACGATTTTGAAACG Q|49|H silent|CAG>CAA|Q|49 MRPL16 Mitochondrial Ribosomal Protein, Large subunit 232.0 0 0 0 0 -0.2217689962978208 P38064 0.13410437107086182 38.3079656441447 35.0 1.0 no 289 chrII_146531 947 high_effect YBL038W 344 + AAACGTTGCTGTATGTATCA N|116|K silent|AAC>AAT|N|116 MRPL16 Mitochondrial Ribosomal Protein, Large subunit 232.0 0 0 0 0 -0.2531906398288599 P38064 0.02782184258103371 42.36138423248383 35.0 1.0 no 290 chrII_146613r 950 high_effect YBL038W 429 - TCGAAAAGGATCTTCCCTGT E|150|Q E|150|K MRPL16 Mitochondrial Ribosomal Protein, Large subunit 232.0 0 0 0 0 -2.3245519099667167 P38064 0.0 0.0 47.62285895988572 45.0 1.0 yes 291 chrII_146695r 953 high_effect YBL038W 511 - TTCATATACCCCAGGTAACT E|177|Q E|177|K MRPL16 Mitochondrial Ribosomal Protein, Large subunit 232.0 0 0 0 0 -0.1351143262566092 P38064 0.03575114533305168 0.027823008596897125 48.99734409607379 40.0 1.0 no 292 chrII_152028 954 essential YBL035C 1563 - TCATTTATTTGAAAAGATGA E|528|Q E|528|K POL12 POLymerase 705.0 0 0 0 0 -0.2537684769568131 P38121 0.039572633802890785 0.031325381249189384 3.5738799571990967 8.56719970703125 31.780076712375546 20.0 0.0 no 293 chrII_152313 960 essential YBL035C 1278 - CCAAACATTATCAAGACGTG G|433|R G|433|S M|431|I M|431|I POL12 POLymerase 705.0 0 0 0 0 -1.40613660189969 P38121 0.0 0.0 0.07908891886472702 0.07908891886472702 10.791119575500488 8.488719940185549 2.7630200386047363 2.7630200386047363 39.59077983741901 40.0 0.0 no 294 chrII_152630 965 essential YBL035C 961 - TCCAACGCCGCCCATTCTTG G|327|R G|327|R G|327|A G|327|E POL12 POLymerase 705.0 0 0 0 0 -1.7228039170935143 P38121 0.0 0.0 0.0 0.0 1.6831599473953247 1.6831599473953247 2.867000102996826 2.7726399898529053 58.38697777549879 60.0 0.0 no 295 chrII_152714 968 essential YBL035C 877 - CCTTCCAACAGCATAAATTT R|299|T R|299|K G|298|A G|298|E POL12 POLymerase 705.0 0 0 0 0 0.6496364308870707 P38121 0.0 0.0 0.0 0.0 2.851680040359497 1.9277800321578982 4.0385799407958975 10.437439918518066 43.55328698941905 35.0 0.0 no 296 chrII_152845r 972 essential YBL035C 743 + AACAATGAGGCAAAACTTAC T|249|R T|249|I POL12 POLymerase 705.0 0 0 0 0 0.44267474705660187 P38121 0.02002793364226818 0.02235955931246281 -1.4005600214004517 0.4239400029182434 -2.01173996925354 -0.4926800131797791 35.45017652375043 35.0 0.0 no 297 chrII_152877 973 essential YBL035C 714 - TACTTTTTAGCATCATAAAA K|244|N silent|AAG>AAA|K|244 POL12 POLymerase 705.0 0 0 0 0 -0.18561462507424856 P38121 0.0 34.014517689680304 20.0 0.0 no 298 chrII_152946r 975 essential YBL035C 642 + TCATCTGGTAATCCAAATGT S|215|* S|215|L S|216|C S|216|F POL12 POLymerase 705.0 0 0 0 0 -0.9006331059234767 P38121 0.7207819223403931 0.11853603273630142 0.32435688376426697 42.79925769778504 35.0 0.0 no 299 chrII_153086 981 essential YBL035C 505 - GGCATCCGAGCTTTTAGCGT A|175|P A|175|T D|174|H D|174|N POL12 POLymerase 705.0 0 1 0 0 0.0488724682187454 P38121 0.2849771082401276 0.5733940005302429 0.3297988772392273 0.5625312328338623 56.940318132274285 55.00000000000001 0.0 no 300 chrII_153207r 986 essential YBL035C 381 + TCCAAGCAAACATATAATGT silent|TCC>TCG|S|128 silent|TCC>TCT|S|128 S|128|C S|128|F POL12 POLymerase 705.0 0 0 0 1 0.30773168936601863 P38121 0.029370004311203964 0.0193020086735487 38.02288158788957 30.0 0.0 no 301 chrII_153575r 991 essential YBL035C 13 + TCGATGTCATCACTCATTTT I|5|M silent|ATC>ATT|I|5 POL12 POLymerase 705.0 0 0 0 0 -0.2633962719033853 P38121 0.10497789829969406 45.112094976896685 35.0 0.0 no 302 chrII_154971 992 essential YBL034C 3399 - TCTGTACTGAATTTTACTGT D|1140|H D|1140|N S|1138|T S|1138|N STU1 Suppressor of TUbulin 1513.0 0 0 0 0 1.093354341264088 P38198 0.9486550092697144 0.956179976463318 0.9512869715690612 0.9536849856376648 0.041112396866083145 0.10165605694055556 0.22230574488639832 0.07456263154745102 40.786132874334726 30.0 0.0 no 303 chrII_155092 994 essential YBL034C 3278 - TATCATCTTCCTCCTTTGCT D|1099|H D|1099|N D|1098|H D|1098|N STU1 Suppressor of TUbulin 1513.0 0 0 0 0 0.2141278917686701 P38198 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.12821528315544128 0.30297696590423584 0.07802519202232361 0.2669229209423065 53.805880843823054 40.0 0.0 no 304 chrII_155097 995 essential YBL034C 3273 - TCTTCCTCCTTTGCTGGGTT D|1098|H D|1098|N E|1097|Q E|1097|K STU1 Suppressor of TUbulin 1513.0 0 0 0 0 0.2062420436397413 P38198 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.07802519202232361 0.2669229209423065 0.4954493045806885 0.6444761753082275 60.1800579682681 50.0 0.0 no 305 chrII_155104r 998 essential YBL034C 3263 + GGACCAGCCAAACCCAGCAA D|1089|E silent|GAC>GAT|D|1089 Q|1090|E Q|1090|* STU1 Suppressor of TUbulin 1513.0 0 0 0 0 0.2392905135740296 P38198 0.9532920122146606 0.9590039849281312 1.0 0.9491600394248962 55.769493489198226 60.0 0.0 no 306 chrII_155255 999 essential YBL034C 3115 - ATCAGTTTCCAAGTTTTTGA D|1045|H D|1045|N STU1 Suppressor of TUbulin 1513.0 0 1 0 0 0.3721740047027841 P38198 0.9486550092697144 0.956179976463318 0.29745855927467346 0.5816419720649719 44.04675906626449 30.0 0.0 no 307 chrII_155776r 1002 essential YBL034C 2591 + TAACTTGATTATAACTATCG N|865|K silent|AAC>AAT|N|865 STU1 Suppressor of TUbulin 1513.0 0 0 0 0 0.6469401904962109 P38198 0.9439849853515624 0.7754652500152588 33.17694323314964 25.0 0.0 no 308 chrII_155789 1004 essential YBL034C 2581 - AATCAAGTTAGTAAGCTCGT L|866|F silent|TTG>TTA|L|866 STU1 Suppressor of TUbulin 1513.0 0 0 0 0 -0.35749667243929345 P38198 0.9587849974632264 0.14772823452949524 41.50310405655063 35.0 0.0 no 309 chrII_155966 1006 essential YBL034C 2404 - GCGTAGCTTTTTCATAATCA R|808|P R|808|H K|806|N silent|AAG>AAA|K|806 STU1 Suppressor of TUbulin 1513.0 0 0 0 0 -0.4470507185514635 P38198 0.9099509716033936 0.9570810198783876 0.9355990290641784 0.01409108191728592 0.015443578362464903 0.5022252202033997 45.17435884874391 35.0 0.0 no 310 chrII_156040r 1007 essential YBL034C 2327 + TGCTTTACAGTATTTACAAA A|777|G A|777|V STU1 Suppressor of TUbulin 1513.0 0 0 0 0 0.02428433650018469 P38198 0.9484469890594482 0.9504740238189696 0.8319779038429259 0.18925565481185916 37.20543562938343 25.0 0.0 no 311 chrII_156132 1008 essential YBL034C 2238 - TTACTGCCTTTTAATGAGAT S|752|T S|752|N G|751|A G|751|D STU1 Suppressor of TUbulin 1513.0 0 0 0 0 -0.16914952469468594 P38198 0.9512869715690612 0.9536849856376648 0.9499930143356324 0.9446240067481996 0.6322332620620728 0.43666210770607 0.8579325079917908 0.6619957685470581 41.71594886516755 30.0 0.0 no 312 chrII_156486 1012 essential YBL034C 1884 - CTTCCACCAGCTGTGACTGC G|634|A G|634|E G|634|R G|634|R STU1 Suppressor of TUbulin 1513.0 0 0 0 0 -0.3935921663541856 P38198 0.9499930143356324 0.9438679814338684 0.941340982913971 0.941340982913971 58.5072020386333 60.0 0.0 no 313 chrII_156620 1021 essential YBL034C 1750 - GTACAATCGAGACGTTGCAG L|589|F silent|TTG>TTA|L|589 STU1 Suppressor of TUbulin 1513.0 0 0 0 0 -0.6870578855506183 P38198 0.9587849974632264 0.0922410860657692 45.57227792777326 50.0 0.0 no 314 chrII_156800 1024 essential YBL034C 1570 - TAACCTCATTGCCTCTCTAA R|529|S silent|AGG>AGA|R|529 R|529|T R|529|K STU1 Suppressor of TUbulin 1513.0 0 0 0 0 0.06392742266166422 P38198 0.9087679982185364 0.932735025882721 0.955805003643036 0.0 0.0 0.0 48.5862292391318 40.0 0.0 no 315 chrII_156803r 1025 essential YBL034C 1564 + CAACCGTTAGAGAGGCAATG T|523|S T|523|I silent|ACC>ACG|T|523 silent|ACC>ACT|T|523 STU1 Suppressor of TUbulin 1513.0 0 0 0 0 -0.20657358481115554 P38198 0.9491789937019348 0.9472420215606691 0.3734770715236664 0.7122408151626587 45.16282568301074 50.0 0.0 no 316 chrII_156883r 1029 essential YBL034C 1484 + AACTTCGCCAACCTCAAAGT T|496|S T|496|I S|497|W S|497|L STU1 Suppressor of TUbulin 1513.0 1 Series([], Name: modification, dtype: object) 0 0 0 -1.2899975673018302 P38198 0.9491789937019348 0.9472420215606691 0.9288619756698608 0.9298099875450134 47.38067423452993 45.0 0.0 no 317 chrII_157126 1030 essential YBL034C 1244 - TCTTGAAAATGACAAATATT K|421|N silent|AAG>AAA|K|421 STU1 Suppressor of TUbulin 1513.0 0 0 0 0 0.9705795114817368 P38198 0.9355990290641784 0.02383178099989891 30.18260016061657 20.0 0.0 no 318 chrII_157150r 1031 essential YBL034C 1217 + TCAGTTGCCCCTATCAATAT Q|407|E Q|407|* STU1 Suppressor of TUbulin 1513.0 0 0 0 0 -1.3769678532854135 P38198 0.9590039849281312 0.9891255497932434 50.93550750279542 40.0 0.0 no 319 chrII_157381 1033 essential YBL034C 989 - GTTCTGTTTCCTTTACACTT E|336|Q E|336|K STU1 Suppressor of TUbulin 1513.0 0 0 0 0 0.5874208496031968 P38198 0.956179976463318 0.9475290179252625 0.0 0.0 49.12369168244072 35.0 0.0 no 320 chrII_157390r 1034 essential YBL034C 977 + GGCACCGTTCCAAAGTGTAA A|327|G A|327|V P|328|A P|328|S STU1 Suppressor of TUbulin 1513.0 0 0 0 0 -0.4756454284316148 P38198 0.9484469890594482 0.9504740238189696 0.9562489986419678 0.9498909711837769 0.011025524698197842 0.6833078265190125 0.0 0.0 50.6320903424966 50.0 0.0 no 321 chrII_157485 1036 essential YBL034C 885 - CTCAAGTTGTTTGATAACTG L|301|F silent|TTG>TTA|L|301 STU1 Suppressor of TUbulin 1513.0 0 0 0 0 -0.5611421567133907 P38198 0.9587849974632264 0.6599173545837402 39.023782837265465 35.0 0.0 no 322 chrII_157499 1037 essential YBL034C 871 - TAACTGCGGCAATTTCGCTT Q|296|H silent|CAG>CAA|Q|296 silent|CCG>CCC|P|295 silent|CCG>CCA|P|295 STU1 Suppressor of TUbulin 1513.0 0 0 0 0 0.2379975981060048 P38198 0.9570760130882264 0.1080739051103592 48.28232478602689 45.0 0.0 no 323 chrII_157538 1038 essential YBL034C 832 - CTCGTACTCTTCGTCAAACA E|284|Q E|284|K E|282|D silent|GAG>GAA|E|282 STU1 Suppressor of TUbulin 1513.0 0 0 0 0 0.2478450186248908 P38198 0.956179976463318 0.9475290179252625 0.94931298494339 0.0 0.0 1.0 46.26499322712015 45.0 0.0 no 324 chrII_157567 1039 essential YBL034C 803 - TATCTTCTTGTGAACCATGC D|274|H D|274|N E|273|Q E|273|K STU1 Suppressor of TUbulin 1513.0 0 0 0 0 1.0938126521172329 P38198 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.13894575834274292 0.5386019945144653 0.5048774480819702 0.786254346370697 46.27753038840586 40.0 0.0 no 325 chrII_157747 1041 essential YBL034C 623 - CATCGTTTGCGTGTTCATTT D|214|H D|214|N STU1 Suppressor of TUbulin 1513.0 0 0 0 0 0.15693827228394694 P38198 0.9486550092697144 0.956179976463318 0.38878870010375977 0.9193481802940368 48.83705962340537 40.0 0.0 no 326 chrII_157902 1043 essential YBL034C 468 - TCTCCGTTTTGGTTTTCACT G|162|A G|162|E D|163|H D|163|N STU1 Suppressor of TUbulin 1513.0 0 0 0 0 0.11778660914419707 P38198 0.9499930143356324 0.9438679814338684 0.9486550092697144 0.956179976463318 52.03326956458204 40.0 0.0 no 327 chrII_158095 1044 essential YBL034C 275 - GCATGGCCACACGTTTGATA M|98|I M|98|I A|97|P A|97|T STU1 Suppressor of TUbulin 1513.0 0 0 0 0 1.1485552014940932 P38198 0.9553959965705872 0.9553959965705872 0.9573720097541808 0.9523990154266356 0.9002759456634521 0.9002759456634521 0.05544764921069145 0.11684750020503998 52.22591220988886 50.0 0.0 no 328 chrII_158250r 1047 essential YBL034C 117 + GCACTGCTTACACGGTTCAA L|41|V silent|CTG>TTG|L|41 A|40|G A|40|V STU1 Suppressor of TUbulin 1513.0 0 0 0 0 -0.7055933085478586 P38198 0.9512209892272948 0.9484469890594482 0.9504740238189696 0.4272902309894562 0.4059234261512756 0.4575643837451935 50.910424460197476 50.0 0.0 no 329 chrII_158302 1050 essential YBL034C 68 - CCTTGAATACGGTATACAAA K|29|N silent|AAG>AAA|K|29 STU1 Suppressor of TUbulin 1513.0 0 0 0 0 0.638173976494188 P38198 0.9355990290641784 0.5269075632095337 39.11640172823007 35.0 0.0 no 330 chrII_158302r 1051 essential YBL034C 65 + CCCTTTGTATACCGTATTCA P|23|R P|23|L P|23|A P|23|S STU1 Suppressor of TUbulin 1513.0 0 0 0 0 0.015107325711527994 P38198 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.036332376301288605 0.03365938737988472 0.2114707976579666 1.0 50.522301937948725 40.0 0.0 no 331 chrII_163292r 1053 essential YBL030C 683 + GGCTTCATTCTTGTTGGGTT A|229|G A|229|V S|230|* S|230|L PET9 PETite 318.0 0 0 0 0 -0.7278999814699072 P18239 0.9672009944915771 0.9664270281791688 0.8566300272941589 0.2605948746204376 0.8633125424385071 0.01273215003311634 -0.008500000461935997 -0.4211600124835968 -0.6416000127792358 0.878000020980835 0.06920000165700912 54.24185800454927 45.0 0.0 no 332 chrII_163437 1058 essential YBL030C 541 - AGCAACACCATCAGATTTTA A|187|P A|187|T V|186|L V|186|I PET9 PETite 318.0 0 1 0 0 1.1007448307620482 P18239 0.9657430052757264 0.9571110010147096 0.9693499803543092 0.9770190119743348 0.3625353872776032 0.7291889786720276 0.5484169125556946 1.0 -0.7400199770927429 0.26069998741149897 -0.9101999998092652 -0.4282400012016296 -0.5950000286102295 0.42500001192092896 -0.7965999841690063 -0.9272000193595886 43.891924640349494 35.0 0.0 no 333 chrII_163494 1059 essential YBL030C 484 - ACGAGCACCACCCTTTTTAG R|168|P R|168|H A|167|P A|167|T PET9 PETite 318.0 0 0 0 0 0.6974659314351905 P18239 0.901601016521454 0.9396970272064208 0.9667009711265564 0.9580690264701844 0.0033504853490740056 0.002527393866330385 0.043411601334810264 0.2531696259975433 0.1536400020122528 0.3292999863624573 -0.13940000534057614 0.9976000189781188 52.76073854772119 50.0 0.0 no 334 chrII_163500 1060 essential YBL030C 478 - ACCACCCTTTTTAGAGGACT G|166|R G|166|S G|166|A G|166|D PET9 PETite 318.0 0 0 0 0 -0.06551584128883713 P18239 0.9381110072135924 0.9584969878196716 0.9572569727897644 0.9439510107040404 0.08395102620124817 0.5084328055381775 0.4968909919261933 0.10005811601877213 -0.3565999865531921 -0.02339999936521053 -0.25200000405311584 -0.16040000319480896 52.3653671692706 45.0 0.0 no 335 chrII_163504r 1062 essential YBL030C 471 + GACTCCAAGTCCTCTAAAAA D|158|E silent|GAC>GAT|D|158 S|159|C S|159|F PET9 PETite 318.0 0 0 0 0 1.4860562356060671 P18239 0.8886929750442505 0.9634199738502502 0.9436050057411194 0.0 0.02706393785774708 0.01820709928870201 3.9428799152374263 -0.4558799862861633 -2.332740068435669 4.553199768066406 35.19940185546875 42.83923877879283 40.0 0.0 no 336 chrII_163505r 1063 essential YBL030C 470 + TGACTCCAAGTCCTCTAAAA D|158|E silent|GAC>GAT|D|158 S|159|C S|159|F PET9 PETite 318.0 0 0 0 0 0.32586793814935594 P18239 0.8886929750442505 0.9634199738502502 0.9436050057411194 0.0 0.02706393785774708 0.01820709928870201 3.9428799152374263 -0.4558799862861633 -2.332740068435669 4.553199768066406 35.19940185546875 44.248280198113775 40.0 0.0 no 337 chrII_163673r 1066 essential YBL030C 302 + AGCTTTGAATTTCGCCTTCA A|102|G A|102|V PET9 PETite 318.0 0 0 0 0 0.22980326132551704 P18239 0.94820898771286 0.9482390284538268 0.010781537741422651 0.0033521517179906373 0.6658999919891357 -0.058699999004602425 -0.006000000052154064 0.06040000170469284 49.502871973938 40.0 0.0 no 338 chrII_163757r 1068 essential YBL030C 218 + TTTCAAGAGAACCGCTACAC F|74|L silent|TTC>TTT|F|74 PET9 PETite 318.0 0 1 0 0 0.7058003070921843 P18239 0.9584370255470276 0.9790010452270508 0.730180025100708 0.33160001039505005 44.213637942974565 45.0 0.0 no 339 chrII_170917r 1077 essential YBL026W 169 - TCTTATAAAAATATTCCTTA R|63|T R|63|K LSM2 Like SM 95.0 0 0 0 0 0.5061495724790058 P38203 0.04333770275115967 0.019323747605085373 0.3500199913978577 -0.2317599952220917 1.7755714654922483 0.8933948874473572 31.988338095854715 15.0 1.0 no 340 chrII_175579r 1079 essential YBL023C 1925 + GCGCTGCTCAATTATTGCTG silent|CGC>CGG|R|643 silent|CGC>CGT|R|643 R|643|G R|643|C MCM2 MiniChromosome Maintenance 868.0 0 0 0 0 -0.6084180472075398 P29469 0.9520599842071532 0.9521039724349976 0.0 0.0 51.11405639515874 50.0 0.0 no 341 chrII_175627r 1081 essential YBL023C 1877 + GCAAAGTATTTCCATTTCCA Q|627|E Q|627|* MCM2 MiniChromosome Maintenance 868.0 0 0 0 0 0.2794850741314542 P29469 1.0024600028991701 0.0 46.46064454145596 35.0 0.0 no 342 chrII_175654r 1082 essential YBL023C 1850 + TACATCTATTCATGAGGCTA T|618|R T|618|I S|619|C S|619|F MCM2 MiniChromosome Maintenance 868.0 0 0 0 0 -0.1003036332545453 P29469 0.8982250094413757 0.9084240198135376 0.9182299971580504 0.9007340073585509 0.004151341971009971 0.028191976249217987 0.0 0.0 43.77446681453909 35.0 0.0 no 343 chrII_176220r 1095 essential YBL023C 1284 + ATCTACAAAAATAACTACGA I|429|M silent|ATC>ATT|I|429 Y|430|* silent|TAC>TAT|Y|430 MCM2 MiniChromosome Maintenance 868.0 0 0 0 0 -0.4982288938811133 P29469 0.988048017024994 0.006426515523344278 31.589904029954372 25.0 0.0 no 344 chrII_176252 1096 essential YBL023C 1255 - TTCTACCTCTTCACCTGGCT E|425|Q E|425|K V|424|L V|424|I MCM2 MiniChromosome Maintenance 868.0 0 0 0 0 -0.7539459448630634 P29469 0.9202449917793274 0.9081959724426271 0.9769399762153624 0.9846090078353882 0.011660908348858356 0.009020816534757614 0.06314481794834137 1.0 57.72014351828437 50.0 0.0 no 345 chrII_176359 1103 essential YBL023C 1148 - GCGTAACCCTTTGATAATTT silent|ACG>ACC|T|389 silent|ACG>ACA|T|389 V|388|L V|388|I MCM2 MiniChromosome Maintenance 868.0 0 0 0 0 0.14277791223962488 P29469 0.9786369800567628 0.9863060116767884 0.4384041726589203 1.0 44.66548532225347 35.0 0.0 no 346 chrII_176457 1104 essential YBL023C 1050 - TCATTAGAATCTTGAAAAAA E|357|Q E|357|K MCM2 MiniChromosome Maintenance 868.0 0 0 0 0 0.4586722464818401 P29469 0.9825940132141112 0.9705449938774108 0.7084285616874695 0.8881945013999939 29.308984571829683 20.0 0.0 no 347 chrII_176562r 1109 essential YBL023C 942 + TCCTCTCTAGTACGCGTCAC silent|TCC>TCG|S|315 silent|TCC>TCT|S|315 S|315|C S|315|F MCM2 MiniChromosome Maintenance 868.0 0 0 0 0 -0.0704711150643837 P29469 0.9077129960060121 0.8902170062065125 0.0011268318630754948 0.0009101369068957863 55.15645208060846 55.00000000000001 0.0 no 348 chrII_176863 1114 essential YBL023C 644 - TTTCATCTGTATATTCCAGC E|221|Q E|221|K D|220|H D|220|N MCM2 MiniChromosome Maintenance 868.0 0 0 0 0 0.8471993740550328 P29469 0.9825940132141112 0.9705449938774108 0.9090110063552856 0.9202449917793274 0.3686347305774689 0.7310124635696411 0.0741303339600563 0.4332585632801056 46.4999013476056 35.0 0.0 no 349 chrII_177125 1119 essential YBL023C 382 - TTCGTCCTCGTCATCTATGT E|134|Q E|134|K D|133|H D|133|N MCM2 MiniChromosome Maintenance 868.0 0 0 0 0 0.1617444364242584 P29469 1.0002599954605105 0.9889079928398132 0.9897220134735109 1.0002599954605105 0.3830207586288452 0.5861233472824097 0.18347208201885226 0.4783768653869629 53.04567363951161 45.0 0.0 no 350 chrII_177363 1121 essential YBL023C 144 - ACTTCATTATCGTCACCTTC V|55|L V|55|I E|54|Q E|54|K MCM2 MiniChromosome Maintenance 868.0 0 0 0 0 0.17053869778911449 P29469 0.995036005973816 1.0020099878311155 1.006500005722046 0.9951429963111876 0.9149523973464966 0.7889283299446106 0.1921846866607666 0.2985012829303741 48.27551036981106 40.0 0.0 no 351 chrII_177364 1122 essential YBL023C 143 - CTTCATTATCGTCACCTTCA E|54|Q E|54|K MCM2 MiniChromosome Maintenance 868.0 0 0 0 0 0.09043117494963067 P29469 1.006500005722046 0.9951429963111876 0.1921846866607666 0.2985012829303741 49.10945287771614 40.0 0.0 no 352 chrII_177435r 1128 essential YBL023C 69 + TCACCTCAGCAACATTTTAG P|25|A P|25|S S|24|* S|24|L MCM2 MiniChromosome Maintenance 868.0 0 1 0 0 -0.25990040332728226 P29469 1.0002000331878662 0.9924110174179076 0.9753659963607788 0.11837220937013625 0.35511070489883423 0.08547577261924744 45.48710830830179 40.0 0.0 no 353 chrII_182487r 1131 essential YBL020W 89 - TTACCAGTTTGGTGAAAAGT V|36|L V|36|I silent|CTG>CTC|L|35 silent|CTG>CTA|L|35 0 0 0 0 0.5769797800034516 P38206 0.9539830088615416 0.9574310183525084 0.8892214298248291 0.9999517798423768 41.81999651977242 35.0 1.0 no 354 chrII_182516 1132 essential YBL020W 115 + TACTAAATAATTTGTTGATC L|40|V silent|CTA>TTA|L|40 0 0 0 0 -0.10630920142107053 P38206 0.9512209892272948 0.0 31.128631682730433 20.0 1.0 no 355 chrII_182539 1133 essential YBL020W 138 + TTTCTGTCGCCCAGAATTTT L|48|V silent|CTG>TTG|L|48 0 0 0 0 -0.29395157098374525 P38206 0.9512209892272948 0.8265800476074219 50.34815000832987 40.0 1.0 no 356 chrII_182548r 1134 essential YBL020W 150 - GCCGTGATACCGAAAATTCT silent|ACG>ACC|T|56 silent|ACG>ACA|T|56 A|57|P A|57|T 0 0 0 0 -0.10394813793237524 P38206 0.9573720097541808 0.9523990154266356 0.16201937198638916 0.5888318419456482 46.12454409397975 45.0 1.0 no 357 chrII_182740 1139 essential YBL020W 339 + GCTTACATTCCGTTTTGGAT A|114|G A|114|V Y|115|* silent|TAC>TAT|Y|115 0 0 0 0 -0.9793331417303192 P38206 0.9484469890594482 0.9504740238189696 1.0 0.024879809468984604 49.37699850944568 40.0 1.0 no 358 chrII_183005 1147 essential YBL020W 604 + AGCAATCCCGCTACCCAATG Q|203|E Q|203|* S|204|C S|204|F 0 0 0 0 -0.3462525029170277 P38206 0.9590039849281312 0.945252001285553 0.9294660091400146 1.0 54.20862305545933 55.00000000000001 1.0 no 359 chrII_183018r 1153 essential YBL020W 620 - CCGATGTGACAACCCCCATT silent|TCG>TCC|S|213 silent|TCG>TCA|S|213 0 0 0 0 -0.3636016041150396 P38206 55.27203327435615 55.00000000000001 1.0 no 360 chrII_183034 1155 essential YBL020W 633 + ACATCGGACATTGACAAAGA T|212|R T|212|I S|213|W S|213|L 0 0 0 0 1.195884586688838 P38206 0.9476869702339172 0.9472420215606691 0.9288619756698608 0.9298099875450134 40.366739737508226 40.0 1.0 no 361 chrII_183327 1160 essential YBL020W 926 + TATCAATTCTTTATGTACTG I|310|M silent|ATC>ATT|I|310 0 0 0 0 0.2642465664311042 P38206 0.9598389863967896 0.16759057343006134 36.44333596177268 25.0 1.0 no 362 chrII_183364 1162 essential YBL020W 963 + TACGCTCTATTGTCGAACTA Y|322|* silent|TAC>TAT|Y|322 A|323|G A|323|V 0 0 0 0 0.08662308647570814 P38206 0.9484469890594482 0.9504740238189696 0.15766815841197968 0.05604011192917824 44.46740705486286 40.0 1.0 no 363 chrII_183569r 1163 essential YBL020W 1171 - AATCAAGAACTGCAATAAAA L|396|F silent|TTG>TTA|L|396 0 0 0 0 0.6124774852559731 P38206 0.9587849974632264 0.05087001994252205 30.929219433594483 25.0 1.0 no 364 chrII_183614r 1164 essential YBL020W 1216 - GACTCTTATAGTGTCCAAAA V|412|L V|412|I R|411|T R|411|K 0 0 0 0 -1.3610250127701886 P38206 0.9539830088615416 0.9574310183525084 0.932735025882721 0.955805003643036 0.8797782063484192 0.6318097710609436 0.6601835489273071 0.7941884994506836 41.35064971810402 35.0 1.0 no 365 chrII_183652r 1165 essential YBL020W 1254 - ATACCATTAAGCGATAAAAA G|424|A G|424|D G|424|R G|424|S 0 0 0 0 -2.5061491960173483 P38206 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.0 0.0 0.0 0.0 33.78993558167838 25.0 1.0 yes 366 chrII_200027r 1170 essential YBL014C 1699 + TCATTGTCGACCATCCCGAA I|567|M silent|ATC>ATT|I|567 0 0 0 0 0.44581635475459225 P32786 0.23125366866588595 52.146343542448285 50.0 0.0 no 367 chrII_200183r 1173 essential YBL014C 1543 + ATCATATAGACGATGAATCT H|516|D H|516|Y 0 0 0 0 0.7294450459470015 P32786 0.2729138135910034 1.0 37.27739132750878 30.0 0.0 no 368 chrII_200245r 1177 essential YBL014C 1481 + CTCAACAGTTCTTGAAATTC S|495|* S|495|L T|496|R T|496|I 0 0 0 0 -0.3183549689001197 P32786 0.13139823079109192 0.5445959568023682 0.4660158455371857 38.8660726069823 35.0 0.0 no 369 chrII_200282 1179 essential YBL014C 1447 - AAACAAGTTTGCTTTCCTAT L|488|F silent|TTG>TTA|L|488 0 0 0 0 0.3128459483946569 P32786 0.04061436280608177 41.67972413429647 30.0 0.0 no 370 chrII_200330 1180 essential YBL014C 1399 - ATGCCGCATCGAATATACAA silent|CGG>CGC|R|472 silent|CGG>CGA|R|472 R|472|P R|472|Q 0 0 0 0 0.06798437761172821 P32786 0.238719254732132 0.6038839221000671 44.0051473287336 40.0 0.0 no 371 chrII_200353r 1183 essential YBL014C 1373 + GCCTGACCATATTCTTCTGG P|459|R P|459|L P|459|A P|459|S 0 0 0 0 -0.4589226059857129 P32786 0.21643389761447904 0.1028270348906517 0.3282927870750427 0.5716369152069092 53.41413154635848 50.0 0.0 no 372 chrII_200397 1185 essential YBL014C 1332 - ATTCTGAGCGTAGTATCATC R|450|T R|450|K 0 0 0 0 1.549319769681281 P32786 0.023974880576133728 0.3169571459293365 45.80136342267622 40.0 0.0 no 373 chrII_200830 1191 essential YBL014C 899 - ATGCAAAATCTACCACCTGA A|306|P A|306|T 0 0 0 0 -2.7322606132912544 P32786 0.0 0.0 44.76019631571523 40.0 0.0 yes 374 chrII_200968r 1198 essential YBL014C 758 + CATCGGGCGGAGATCAAACC I|254|M silent|ATC>ATT|I|254 0 0 0 0 0.34794515764757905 P32786 0.2733924686908722 50.21545379186642 60.0 0.0 no 375 chrII_201004r 1205 essential YBL014C 722 + TATCAAGAGTATTAAGATAC I|242|M silent|ATC>ATT|I|242 0 0 0 0 0.2851177898397121 P32786 0.0 31.89806649205235 25.0 0.0 no 376 chrII_201043 1206 essential YBL014C 686 - TACTCGTTACATTGTTATGT S|235|T S|235|N silent|ACG>ACC|T|234 silent|ACG>ACA|T|234 0 0 0 0 -0.524290038066793 P32786 0.2996923327445984 0.5464031696319579 42.04437340672779 30.0 0.0 no 377 chrII_201402 1213 essential YBL014C 327 - TTCGGTACCACGGGTATCAC silent|CCG>CCC|P|115 silent|CCG>CCA|P|115 0 0 0 0 -1.597770418597518 P32786 52.64674331168453 55.00000000000001 0.0 no 378 chrII_201476 1216 essential YBL014C 253 - GCTAGTTATGAGATCATCGT S|91|T S|91|N 0 0 0 0 -1.1195444430793424 P32786 0.4052599668502808 0.4060400724411011 46.013563826014654 40.0 0.0 no 379 chrII_201506 1217 essential YBL014C 223 - TTCTTGCAAAACCTTGTCGT E|81|Q E|81|K L|79|F silent|TTG>TTA|L|79 0 0 0 0 1.3948500928883236 P32786 0.4795483946800232 0.7103127837181091 0.7153359651565552 46.47933270081803 40.0 0.0 no 380 chrII_201559 1218 essential YBL014C 170 - GACTTTTGACCACTATATGA S|63|T S|63|N 0 0 0 0 1.1310443538384276 P32786 0.5953672528266907 0.4957515597343445 42.6673307093692 35.0 0.0 no 381 chrII_201609 1221 essential YBL014C 120 - TCTACTGGTCTTAGCCATTG D|47|H D|47|N V|46|L V|46|I 0 0 0 0 0.4672387149634043 P32786 0.0804714560508728 0.2430426031351089 0.667828381061554 0.5422918200492859 50.64642801131259 45.0 0.0 no 382 chrII_201645 1223 essential YBL014C 84 - TTCGTAGTGTAATTTTCTTG silent|ACG>ACC|T|34 silent|ACG>ACA|T|34 0 0 0 0 1.0102950372285169 P32786 40.3291918163211 30.0 0.0 no 383 chrII_201711r 1225 essential YBL014C 15 + ATTCCAAGCTCAGATGTGTT P|7|A P|7|S P|7|R P|7|L 0 0 0 0 -0.05354475223896485 P32786 0.0 0.0 0.0 0.0 48.688352920509494 40.0 0.0 no 384 chrII_213668 1230 high_effect YBL007C 2679 - TGCATACCAAAAGTTGTTTG M|899|I M|899|I G|898|A G|898|D SLA1 Synthetic Lethal with ABP1 1244.0 0 1 0 0 0.12134386502538758 P32790 0.9553959965705872 0.9553959965705872 0.9499930143356324 0.9446240067481996 0.34517765045166016 0.34517765045166016 0.0 0.0 40.730929245181706 35.0 0.0 no 385 chrII_213751 1232 high_effect YBL007C 2596 - CATCACAAAGCCAGTAGATA silent|GTG>GTC|V|871 silent|GTG>GTA|V|871 V|871|L V|871|M SLA1 Synthetic Lethal with ABP1 1244.0 0 0 0 1 -0.18879513583682864 P32790 0.9539830088615416 0.9587630033493042 0.2983172237873077 0.03620833903551102 43.19331499434821 40.0 0.0 no 386 chrII_213923 1237 high_effect YBL007C 2424 - GCTGCCTTTTTAGGTTCTAA A|815|P A|815|T A|814|P A|814|T SLA1 Synthetic Lethal with ABP1 1244.0 0 1 0 0 1.364909490084655 P32790 0.9573720097541808 0.9523990154266356 0.9573720097541808 0.9523990154266356 0.2482614815235138 0.3199643790721893 0.15064737200737 0.2518766224384308 50.75857952149442 40.0 0.0 no 387 chrII_214175r 1245 high_effect YBL007C 2169 + TCAATTCCTACAAATGCCAC S|724|* S|724|L P|726|A P|726|S SLA1 Synthetic Lethal with ABP1 1244.0 0 0 0 0 -0.20423204303006806 P32790 0.9298099875450134 0.9562489986419678 0.9498909711837769 0.2323223352432251 0.7556878328323364 0.727493166923523 44.333640210893975 40.0 0.0 no 388 chrII_214268r 1247 high_effect YBL007C 2076 + AACTCAATGTTAAGAACCTT N|693|K silent|AAC>AAT|N|693 S|694|* S|694|L SLA1 Synthetic Lethal with ABP1 1244.0 0 0 0 0 0.5223958916357244 P32790 0.9439849853515624 0.9298099875450134 0.3399903476238251 0.08424694836139679 -0.2966600060462952 -0.2236800044775009 37.99939729817925 30.0 0.0 no 389 chrII_214269r 1248 high_effect YBL007C 2075 + TAACTCAATGTTAAGAACCT N|693|K silent|AAC>AAT|N|693 S|694|* S|694|L SLA1 Synthetic Lethal with ABP1 1244.0 0 0 0 0 -4.203204309954489 P32790 0.9439849853515624 0.9298099875450134 0.3399903476238251 0.08424694836139679 -0.2966600060462952 -0.2236800044775009 37.2555746695101 30.0 0.0 yes 390 chrII_214524 1254 high_effect YBL007C 1823 - ACCTTGATCTTTCTTCATCT R|614|T R|614|K R|614|S silent|AGG>AGA|R|614 SLA1 Synthetic Lethal with ABP1 1244.0 0 1 0 0 0.9736499940359132 P32790 0.932735025882721 0.955805003643036 0.9087679982185364 0.2409257739782333 0.9215638041496276 0.11594283580780028 48.53840491146843 35.0 0.0 no 391 chrII_214687 1258 high_effect YBL007C 1660 - ATTCGCCTTAAATTTCTCTA silent|GCG>GCC|A|559 silent|GCG>GCA|A|559 A|559|P A|559|T SLA1 Synthetic Lethal with ABP1 1244.0 0 0 0 1 0.4186070755202364 P32790 0.9573720097541808 0.9523990154266356 0.7693343758583069 0.4665101766586304 -0.6449599862098694 0.7954400181770325 43.28107592792856 30.0 0.0 no 392 chrII_214866r 1263 high_effect YBL007C 1478 + TCCAAAAAAATCGCGTCTAT P|494|R P|494|L P|494|A P|494|S SLA1 Synthetic Lethal with ABP1 1244.0 0 1 0 0 -0.9188064214241428 P32790 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.16449207067489624 0.2328101545572281 1.0 0.6443619132041931 39.065515726667 35.0 0.0 no 393 chrII_214939 1264 high_effect YBL007C 1408 - ACTTTTTCTTGACCTTTTAC S|476|T S|476|N SLA1 Synthetic Lethal with ABP1 1244.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.3510607508492992 P32790 0.9512869715690612 0.9536849856376648 0.6356852054595947 0.5191673636436462 43.551128863908154 30.0 0.0 no 394 chrII_215047r 1269 high_effect YBL007C 1297 + ACTTCACCAAATCTCCATCT N|433|K silent|AAC>AAT|N|433 F|434|L silent|TTC>TTT|F|434 SLA1 Synthetic Lethal with ABP1 1244.0 0 1 0 0 0.24023669410721984 P32790 0.9439849853515624 0.9387490153312684 1.0 0.4307185709476471 48.2619572173254 40.0 0.0 no 395 chrII_215326 1277 high_effect YBL007C 1021 - TTCTCTCAACCCAGGATCAC E|347|Q E|347|K R|346|T R|346|K SLA1 Synthetic Lethal with ABP1 1244.0 0 0 0 0 -0.7853731397326746 P32790 0.956179976463318 0.9475290179252625 0.932735025882721 0.955805003643036 0.0 0.0 0.012737171724438669 0.2915907800197601 0.3326999843120575 -0.9941700100898744 51.81711181694829 50.0 0.0 no 396 chrII_215575r 1282 high_effect YBL007C 769 + ACGTTACCGAAATCGAGGGA N|257|K silent|AAC>AAT|N|257 T|259|S T|259|I SLA1 Synthetic Lethal with ABP1 1244.0 0 0 0 0 -0.15722746510019925 P32790 0.9439849853515624 0.9491789937019348 0.9472420215606691 0.2451289147138596 0.9533185362815856 0.19456663727760315 46.09544714450141 50.0 0.0 no 397 chrII_215843 1288 high_effect YBL007C 504 - GCTCTATCATTGTGTTGAGG R|174|T R|174|K A|175|P A|175|T SLA1 Synthetic Lethal with ABP1 1244.0 0 0 0 0 0.6582976235588643 P32790 0.932735025882721 0.955805003643036 0.9573720097541808 0.9523990154266356 0.1849239021539688 1.0 1.0 0.5157871842384338 48.82952046539293 45.0 0.0 no 398 chrII_216008r 1295 high_effect YBL007C 336 + TCTACCGTTTCCAATGAATT S|113|C S|113|F T|114|S T|114|I SLA1 Synthetic Lethal with ABP1 1244.0 0 0 0 0 0.3312462543692947 P32790 0.945252001285553 0.9294660091400146 0.9491789937019348 0.9472420215606691 0.027583817020058632 0.02616017684340477 0.6482408046722412 0.1777646690607071 44.5939566660989 35.0 0.0 no 399 chrII_216277 1301 high_effect YBL007C 70 - CAACAGATCGTCTTCTTGGA silent|CTG>CTC|L|29 silent|CTG>CTA|L|29 SLA1 Synthetic Lethal with ABP1 1244.0 0 0 0 0 0.035529186369162025 P32790 46.522423321289246 45.0 0.0 no 400 chrII_216778 1309 high_effect YBL006C 332 - CAGCTTTGCATTCTAATGTG A|117|P A|117|T LDB7 Low Dye Binding 180.0 0 0 0 0 0.448769361797256 P38210 0.2578681409358978 0.4904536902904511 45.05632204762242 40.0 0.0 no 401 chrII_216887 1313 high_effect YBL006C 223 - ATACTCCACCTGTGCCGCAT E|80|D silent|GAG>GAA|E|80 E|80|Q E|80|K LDB7 Low Dye Binding 180.0 0 0 0 0 -0.5694064805612552 P38210 0.6087549328804016 0.5191660523414612 0.775147557258606 58.682306214095384 55.00000000000001 0.0 no 402 chrII_217000r 1321 high_effect YBL006C 107 + ACAATCTCATGCTACCGACA Q|37|E Q|37|* S|38|C S|38|F LDB7 Low Dye Binding 180.0 0 0 0 0 0.6560801346089826 P38210 0.8794776797294617 0.05254710838198662 0.05084170773625374 47.777446335632646 45.0 0.0 no 403 chrII_227688r 1324 essential YBL004W 55 - ATCGTCAATCCTAGCCTTGA D|25|H D|25|N D|24|H D|24|N UTP20 U Three Protein 2493.0 0 0 0 0 -0.4891760034885775 P35194 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.07480941712856293 0.3902084827423096 0.012346337549388409 0.20581819117069244 51.575319648261775 45.0 1.0 no 404 chrII_227775 1326 essential YBL004W 139 + TTCTCGCTTCCTTTGATCAG L|48|V L|48|F silent|CTC>CTG|L|48 silent|CTC>CTT|L|48 UTP20 U Three Protein 2493.0 0 0 0 0 -0.8056892725418254 P35194 0.9512209892272948 0.9587849974632264 0.10212013870477676 0.06734589487314224 51.20431745012411 45.0 1.0 no 405 chrII_227990r 1329 essential YBL004W 357 - TCATAAAATTTAAGAAAATC E|126|Q E|126|K UTP20 U Three Protein 2493.0 0 0 0 0 -0.8596982197841609 P35194 0.956179976463318 0.9475290179252625 0.5605271458625793 0.8825123906135559 25.09319656159784 15.0 1.0 no 406 chrII_228064 1330 essential YBL004W 428 + GTCATCTAATGTTTTTGAGT S|144|* S|144|L S|145|C S|145|F UTP20 U Three Protein 2493.0 0 0 0 0 -0.1647088862026041 P35194 0.9298099875450134 0.945252001285553 0.9294660091400146 0.03936642408370972 0.04082835838198662 0.020431790500879288 41.891855701386135 30.0 1.0 no 407 chrII_228169 1331 essential YBL004W 533 + TCCACTATTGTCTCATTCTA P|179|R P|179|L P|179|A P|179|S UTP20 U Three Protein 2493.0 0 0 0 0 -0.1348619418349803 P35194 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.028440790250897408 0.015027718618512154 0.06112699955701827 0.07810848206281662 47.68545708315668 35.0 1.0 no 408 chrII_228305 1335 essential YBL004W 669 + GAGCAAACTAACCTCTACGA Q|225|E Q|225|* UTP20 U Three Protein 2493.0 0 0 0 0 0.92301245709014 P35194 0.9590039849281312 1.0 43.9161152757356 45.0 1.0 no 409 chrII_228306 1337 essential YBL004W 670 + AGCAAACTAACCTCTACGAA Q|225|E Q|225|* T|226|S T|226|I UTP20 U Three Protein 2493.0 0 0 0 0 0.01938927211037433 P35194 0.9590039849281312 0.9491789937019348 0.9472420215606691 1.0 0.8687773346900941 0.5574470162391663 41.48971127941115 40.0 1.0 no 410 chrII_228450 1341 essential YBL004W 814 + TTTCATTGCTCTCAGATATT S|273|* S|273|L UTP20 U Three Protein 2493.0 0 0 0 0 0.042066047233537816 P35194 0.9298099875450134 0.012829095125198364 43.7809988485194 30.0 1.0 no 411 chrII_228814r 1345 essential YBL004W 1181 - AAGCAAATTGAAAGAATTCA A|400|P A|400|T UTP20 U Three Protein 2493.0 0 0 0 0 -0.3698294181631132 P35194 0.9573720097541808 0.9523990154266356 0.22577737271785736 0.7364562749862671 31.920346501492478 25.0 1.0 no 412 chrII_229616 1354 essential YBL004W 1980 + TTCTTTCTCAAATACTTATT F|661|L silent|TTC>TTT|F|661 L|663|V L|663|F UTP20 U Three Protein 2493.0 0 0 0 0 0.11855387608601288 P35194 0.9387490153312684 0.9512209892272948 0.9587849974632264 0.33286067843437195 1.0 0.23897022008895874 36.375688287327755 20.0 1.0 no 413 chrII_229647 1355 essential YBL004W 2011 + CCGTTAGATTCTCTCCAGTT silent|ACC>ACG|T|671 silent|ACC>ACT|T|671 UTP20 U Three Protein 2493.0 0 0 0 0 -0.08503487833551793 P35194 53.00072416655081 45.0 1.0 no 414 chrII_229661r 1356 essential YBL004W 2028 - TCAAAAACACCAGTCCAAAC D|683|H D|683|N UTP20 U Three Protein 2493.0 0 0 0 0 0.4032343188131749 P35194 0.9486550092697144 0.956179976463318 0.007159467786550522 0.015431026928126812 39.62736899311057 40.0 1.0 no 415 chrII_229754r 1358 essential YBL004W 2121 - TCCAAATTTTGATTTTCATC L|713|F silent|TTG>TTA|L|713 D|714|H D|714|N UTP20 U Three Protein 2493.0 0 0 0 0 -0.34914010315062954 P35194 0.9587849974632264 0.9486550092697144 0.956179976463318 0.3918147385120392 0.11149734258651732 0.4884574115276337 38.43715975822533 25.0 1.0 no 416 chrII_229938r 1362 essential YBL004W 2305 - TCTAATTAAAATTGGGTAGG R|775|T R|775|K UTP20 U Three Protein 2493.0 0 0 0 0 -0.2021843939422326 P35194 0.932735025882721 0.955805003643036 0.011427841149270536 0.16172659397125244 35.01631352995071 30.0 1.0 no 417 chrII_230082 1366 essential YBL004W 2446 + AACGTGTTATTACTGGTTCA R|817|G R|817|C UTP20 U Three Protein 2493.0 0 0 0 0 0.2144690793897286 P35194 0.8994590044021606 0.8926740288734436 0.3845124244689941 0.0863509401679039 43.56025545422534 35.0 1.0 no 418 chrII_230215r 1367 essential YBL004W 2582 - GCTTCTGAACGTCTGTATTA K|867|N silent|AAG>AAA|K|867 Q|866|H silent|CAG>CAA|Q|866 UTP20 U Three Protein 2493.0 0 0 0 0 0.8225214572622113 P35194 0.9355990290641784 0.9570760130882264 0.050722572952508926 0.0 46.1594235709577 40.0 1.0 no 419 chrII_230270r 1369 essential YBL004W 2637 - TCTCTATATTTATTCAACGT R|885|T R|885|K D|886|H D|886|N UTP20 U Three Protein 2493.0 0 0 0 0 0.6508493927053736 P35194 0.932735025882721 0.955805003643036 0.9486550092697144 0.956179976463318 0.024877024814486504 0.8614705204963684 0.0 0.0 38.835924856654906 25.0 1.0 no 420 chrII_230308 1370 essential YBL004W 2672 + ACTAGATGACACCTTATTCA L|892|V silent|CTA>TTA|L|892 UTP20 U Three Protein 2493.0 0 0 0 0 1.5417657589739946 P35194 0.9512209892272948 0.0 43.53355570618686 35.0 1.0 no 421 chrII_230432 1374 essential YBL004W 2796 + GCACAAGTCCCCCCAACTAG Q|934|E Q|934|* A|933|G A|933|V UTP20 U Three Protein 2493.0 0 0 0 0 -0.6262848330393537 P35194 0.9590039849281312 0.9484469890594482 0.9504740238189696 0.0 0.21300208568573 1.0 57.69883985406187 60.0 1.0 no 422 chrII_230442r 1375 essential YBL004W 2809 - TCTTTTCTGTCCACTAGTTG R|943|T R|943|K Q|941|H silent|CAG>CAA|Q|941 UTP20 U Three Protein 2493.0 0 0 0 0 -1.6966468826775152 P35194 0.932735025882721 0.955805003643036 0.9570760130882264 0.5376604199409485 1.0 0.16026850044727325 49.26651226526071 40.0 1.0 no 423 chrII_230443r 1376 essential YBL004W 2810 - TTCTTTTCTGTCCACTAGTT R|943|T R|943|K UTP20 U Three Protein 2493.0 0 0 0 0 -1.7300842620134531 P35194 0.932735025882721 0.955805003643036 0.5376604199409485 1.0 49.60381593594025 35.0 1.0 no 424 chrII_230444r 1377 essential YBL004W 2811 - CTTCTTTTCTGTCCACTAGT R|943|T R|943|K UTP20 U Three Protein 2493.0 0 0 0 0 -0.5005801375521255 P35194 0.932735025882721 0.955805003643036 0.5376604199409485 1.0 51.312463823354285 40.0 1.0 no 425 chrII_230510r 1378 essential YBL004W 2877 - CTCAAAAAATCATTAATATA L|965|F silent|TTG>TTA|L|965 UTP20 U Three Protein 2493.0 0 0 0 0 0.06060358508753064 P35194 0.9587849974632264 0.041318170726299286 27.300676123039807 15.0 1.0 no 426 chrII_230578 1379 essential YBL004W 2942 + CCATCAAATAAATAGCTCAA H|982|D H|982|Y Q|983|E Q|983|* UTP20 U Three Protein 2493.0 0 0 0 0 -0.11495634545125424 P35194 0.9473130106925964 0.9489949941635132 0.9590039849281312 0.6407520174980164 0.5291063785552979 0.8520500659942627 36.661767066769464 30.0 1.0 no 427 chrII_230578r 1380 essential YBL004W 2945 - CCTTTGAGCTATTTATTTGA K|988|N silent|AAG>AAA|K|988 UTP20 U Three Protein 2493.0 0 0 0 0 0.9328933967004888 P35194 0.9355990290641784 0.5584957003593445 43.257202676257926 30.0 1.0 no 428 chrII_230786 1382 essential YBL004W 3150 + GCAAGTAATTTAAGGCAACA A|1051|G A|1051|V UTP20 U Three Protein 2493.0 0 0 0 0 0.16525908611867035 P35194 0.9484469890594482 0.9504740238189696 0.035005997866392136 0.11647561192512512 39.556933965862925 35.0 1.0 no 429 chrII_230899 1384 essential YBL004W 3263 + GCCTCGTATTTCACATTTTT P|1089|R P|1089|L P|1089|A P|1089|S UTP20 U Three Protein 2493.0 0 0 0 0 0.03631436807441568 P35194 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 48.396833463268024 35.0 1.0 no 430 chrII_230981r 1385 essential YBL004W 3348 - TACAAAAACTGGTACAGAGA L|1122|F silent|TTG>TTA|L|1122 UTP20 U Three Protein 2493.0 0 0 0 0 -0.7537323943817629 P35194 0.9587849974632264 0.0 35.8948850337332 35.0 1.0 no 431 chrII_231016 1387 essential YBL004W 3380 + TGCAACTGCCACTGCATTGA A|1128|G A|1128|V T|1129|S T|1129|I UTP20 U Three Protein 2493.0 0 0 0 0 -0.2794489768335256 P35194 0.9484469890594482 0.9504740238189696 0.9491789937019348 0.9472420215606691 0.050966788083314896 0.033374447375535965 0.7098925709724426 0.2902419865131378 52.116456544304754 50.0 1.0 no 432 chrII_231052r 1388 essential YBL004W 3419 - TAACAGCTTCCTTAACGTGT V|1146|L V|1146|I A|1145|P A|1145|T UTP20 U Three Protein 2493.0 0 0 0 0 1.3744681004796615 P35194 0.9539830088615416 0.9574310183525084 0.9573720097541808 0.9523990154266356 0.0 0.0 0.3335067629814148 0.7382780909538269 46.21186320537919 40.0 1.0 no 433 chrII_231079r 1390 essential YBL004W 3446 - AGTCCGCCGCTTCAATTATT D|1155|H D|1155|N silent|GCG>GCC|A|1154 silent|GCG>GCA|A|1154 UTP20 U Three Protein 2493.0 0 0 0 0 0.4624594062059111 P35194 0.9486550092697144 0.956179976463318 0.15195246040821075 0.5047317743301392 52.61038691862649 45.0 1.0 no 434 chrII_231483r 1394 essential YBL004W 3850 - TTCTATGAAGAGCTCTGTCA E|1290|Q E|1290|K UTP20 U Three Protein 2493.0 0 0 0 0 0.0820526127525021 P35194 0.956179976463318 0.9475290179252625 0.3920745849609375 0.7822014093399048 45.93275711715643 40.0 1.0 no 435 chrII_231648r 1398 essential YBL004W 4015 - TAACCACTCTAACTCACTGT W|1344|C W|1344|* W|1344|S W|1344|* UTP20 U Three Protein 2493.0 0 0 0 0 -0.8223381279104892 P35194 0.8858469724655151 0.8858469724655151 0.0 0.0 45.09075178307943 40.0 1.0 no 436 chrII_231850 1400 essential YBL004W 4214 + CCTCAGAGACTCCCTAGAAG silent|CTC>CTG|L|1406 silent|CTC>CTT|L|1406 L|1406|V L|1406|F UTP20 U Three Protein 2493.0 0 0 0 0 -0.1500419160334358 P35194 0.9512209892272948 0.9587849974632264 0.09763499349355698 0.0445818193256855 51.70523973502407 55.00000000000001 1.0 no 437 chrII_231861r 1402 essential YBL004W 4228 - CTCACTTTGTACCTCTTCTA E|1416|Q E|1416|K S|1415|T S|1415|N UTP20 U Three Protein 2493.0 0 0 0 0 -0.5814888271938675 P35194 0.956179976463318 0.9475290179252625 0.9512869715690612 0.9536849856376648 0.0 0.0 1.0 0.4949595928192138 49.89121044737863 40.0 1.0 no 438 chrII_231862r 1403 essential YBL004W 4229 - ACTCACTTTGTACCTCTTCT E|1416|Q E|1416|K E|1416|D silent|GAG>GAA|E|1416 UTP20 U Three Protein 2493.0 0 0 0 0 -1.4633979356771447 P35194 0.956179976463318 0.9475290179252625 0.94931298494339 0.0 0.0 0.0 50.98764833501957 40.0 1.0 no 439 chrII_231925 1404 essential YBL004W 4289 + TTTCACCGACTTCGAAGATA F|1431|L silent|TTC>TTT|F|1431 T|1432|S T|1432|I UTP20 U Three Protein 2493.0 0 0 0 0 1.391839420006503 P35194 0.9387490153312684 0.9491789937019348 0.9472420215606691 0.05377322807908058 0.1945437788963318 0.007914005778729916 43.965069853143866 40.0 1.0 no 440 chrII_231948r 1405 essential YBL004W 4315 - ATCACCATTGTACAGTAAAA D|1445|H D|1445|N G|1444|A G|1444|D UTP20 U Three Protein 2493.0 0 0 0 0 -0.8493144415415202 P35194 0.9486550092697144 0.956179976463318 0.9499930143356324 0.9446240067481996 0.04912365227937698 0.19048701226711276 0.16607069969177246 0.8649593591690063 38.81709560510286 30.0 1.0 no 441 chrII_232099 1407 essential YBL004W 4463 + GATCGAACATTATGTCTTTT I|1489|M silent|ATC>ATT|I|1489 UTP20 U Three Protein 2493.0 0 0 0 0 1.1742456572179836 P35194 0.9598389863967896 0.008320781402289867 39.9212117768123 30.0 1.0 no 442 chrII_232242r 1413 essential YBL004W 4609 - TTGCTTCATTTGGTTAGGCT K|1542|N silent|AAG>AAA|K|1542 M|1541|I M|1541|I UTP20 U Three Protein 2493.0 0 0 0 0 -0.2163578556162232 P35194 0.9355990290641784 0.9553959965705872 0.9553959965705872 0.014652966521680357 0.11108892410993576 0.11108892410993576 51.0564228818049 40.0 1.0 no 443 chrII_232295r 1415 essential YBL004W 4662 - ATACGAAGAGTTTCTCTAAG R|1560|P R|1560|H UTP20 U Three Protein 2493.0 0 0 0 0 0.6184434139635099 P35194 0.9099509716033936 0.9570810198783876 0.27658960223197937 0.13530489802360535 37.993261250287155 35.0 1.0 no 444 chrII_232575r 1422 essential YBL004W 4942 - TACTGCATCTCTTAATTCTT V|1654|L V|1654|I A|1653|P A|1653|T UTP20 U Three Protein 2493.0 0 0 0 0 0.1487489294073864 P35194 0.9539830088615416 0.9574310183525084 0.9573720097541808 0.9523990154266356 0.11437493562698366 0.407688707113266 0.021012350916862488 0.15197588503360748 42.92943304836115 30.0 1.0 no 445 chrII_232717r 1423 essential YBL004W 5084 - GCATACTCTTTAATATGTAG M|1701|I M|1701|I S|1700|T S|1700|N UTP20 U Three Protein 2493.0 0 0 0 0 -0.04767834841363633 P35194 0.9553959965705872 0.9553959965705872 0.9512869715690612 0.9536849856376648 1.0 1.0 0.913376808166504 0.4586351215839386 38.40585294577494 30.0 1.0 no 446 chrII_232721 1424 essential YBL004W 5085 + TACATATTAAAGAGTATGCA Y|1696|* silent|TAC>TAT|Y|1696 UTP20 U Three Protein 2493.0 0 0 0 0 0.2744316986570293 P35194 34.941716310618745 25.0 1.0 no 447 chrII_232744 1425 essential YBL004W 5108 + AGTCTTAAAACACTCCGATT silent|GTC>GTG|V|1704 silent|GTC>GTT|V|1704 UTP20 U Three Protein 2493.0 0 0 0 0 1.04482190051864 P35194 41.49767241899133 35.0 1.0 no 448 chrII_232908r 1427 essential YBL004W 5275 - TTCTGTCAGGCTGATGTTTG E|1765|Q E|1765|K silent|CTG>CTC|L|1763 silent|CTG>CTA|L|1763 UTP20 U Three Protein 2493.0 0 0 0 0 -0.4090866506807265 P35194 0.956179976463318 0.9475290179252625 0.7503738999366759 0.8985587954521179 49.71189154311537 45.0 1.0 no 449 chrII_232936 1428 essential YBL004W 5300 + AACATTACTCTCTCCTGTGA T|1768|R T|1768|I UTP20 U Three Protein 2493.0 0 0 0 0 0.8931894282981584 P35194 0.9476869702339172 0.9472420215606691 0.4267808794975281 0.421870082616806 47.50576184059969 40.0 1.0 no 450 chrII_232949r 1429 essential YBL004W 5316 - ACCATCAACAAAGCCTTCAC M|1778|I M|1778|I V|1779|L V|1779|I UTP20 U Three Protein 2493.0 0 0 0 0 -0.06597209793152335 P35194 0.9553959965705872 0.9553959965705872 0.9539830088615416 0.9574310183525084 0.1989741325378418 0.1989741325378418 0.03416348993778229 0.03037786297500133 46.55395621405757 45.0 1.0 no 451 chrII_233202r 1432 essential YBL004W 5569 - AAGCAAACTGTTTGAGTTGA L|1862|F silent|TTG>TTA|L|1862 UTP20 U Three Protein 2493.0 0 0 0 0 -0.059771189339098224 P35194 0.9587849974632264 0.022533565759658813 40.294495383370254 35.0 1.0 no 452 chrII_241912 1433 essential YBR002C 637 - TATCAAAAAGTCACTTAATC L|218|F silent|TTG>TTA|L|218 RER2 Retention in the Endoplasmic Reticulum 286.0 0 0 0 0 0.06952570748150755 P35196 0.9587849974632264 0.028953710570931438 31.814530263706327 25.0 0.0 no 453 chrII_241974r 1434 essential YBR002C 572 + ATCGCATCTCTACACGGCGG S|192|W S|192|L H|193|D H|193|Y RER2 Retention in the Endoplasmic Reticulum 286.0 0 0 0 0 -0.9340179411062152 P35196 0.9288619756698608 0.9298099875450134 0.9473130106925964 0.9489949941635132 0.012772657908499241 0.19523848593235016 0.2756074368953705 0.3631518483161926 3.525279998779297 7.001140117645264 53.96206787056338 60.0 0.0 no 454 chrII_242024r 1436 essential YBR002C 522 + ACAATTGTTCAACATAAGAA T|175|R T|175|I RER2 Retention in the Endoplasmic Reticulum 286.0 0 0 0 0 1.2096334359186094 P35196 0.9476869702339172 0.9472420215606691 0.023156946524977684 0.8977693319320679 33.47974301863161 25.0 0.0 no 455 chrII_242143r 1440 essential YBR002C 403 + AGTCTCTATTAGAAGATGTT S|136|C S|136|F L|137|V silent|CTA>TTA|L|137 RER2 Retention in the Endoplasmic Reticulum 286.0 0 1 0 0 -2.24149295035977 P35196 0.945252001285553 0.9294660091400146 0.9512209892272948 0.0038504954427480693 0.003022563178092241 1.0 0.4056200087070465 39.96513733595265 30.0 0.0 yes 456 chrII_242169r 1441 essential YBR002C 377 + TATCGGCGATCTCTCTTTGT I|127|M silent|ATC>ATT|I|127 silent|GGC>GGG|G|128 silent|GGC>GGT|G|128 RER2 Retention in the Endoplasmic Reticulum 286.0 0 0 0 0 -0.5346555486564949 P35196 0.9598389863967896 0.026422979310154915 1.1466799974441528 50.97515114582922 45.0 0.0 no 457 chrII_242379 1443 essential YBR002C 170 - TACTAACAAATCCTGCCTCG S|63|T S|63|N V|62|L V|62|I RER2 Retention in the Endoplasmic Reticulum 286.0 0 0 0 0 0.40599393533654426 P35196 0.9512869715690612 0.9536849856376648 0.9539830088615416 0.9574310183525084 0.9806187152862548 0.12245488911867143 0.11766029149293901 0.07012933492660522 -0.8094199895858765 -0.8081799745559692 45.63394963267848 45.0 0.0 no 458 chrII_242462r 1445 essential YBR002C 84 + AACTGTGTACCTAGACATGT N|29|K silent|AAC>AAT|N|29 RER2 Retention in the Endoplasmic Reticulum 286.0 0 0 0 0 0.7721614060119968 P35196 0.9439849853515624 0.09294676780700684 45.576914537967816 40.0 0.0 no 459 chrII_242461r 1446 essential YBR002C 85 + ACTGTGTACCTAGACATGTT N|29|K silent|AAC>AAT|N|29 RER2 Retention in the Endoplasmic Reticulum 286.0 0 0 0 0 -0.19664342044609887 P35196 0.9439849853515624 0.09294676780700684 47.48445202369765 40.0 0.0 no 460 chrII_244750 1448 essential YBR004C 898 - CCAATAATGACTCTGAATGT W|306|S W|306|* 0 0 0 0 -3.218278767325632 P38211 0.8858469724655151 0.0 39.588629560904344 35.0 0.0 yes 461 chrII_244820 1449 essential YBR004C 828 - TTACACCATTCACCCCTTTG C|282|S C|282|Y W|281|C W|281|* 0 0 0 0 -1.9267830000035595 P38211 0.9421560168266296 0.9290120005607604 0.8858469724655151 0.0 0.0 0.0 52.723376818462725 45.0 0.0 no 462 chrII_244984r 1451 essential YBR004C 661 + GTTCAAACTGTGTTTTGTTA S|222|* S|222|L 0 0 0 0 -0.5124446218241349 P38211 0.9298099875450134 0.07839294523000717 41.39996292237839 30.0 0.0 no 463 chrII_245087r 1454 essential YBR004C 558 + TCCATTTCCGTGCCCGTATT silent|TCC>TCG|S|187 silent|TCC>TCT|S|187 S|187|C S|187|F 0 0 0 0 0.9878222719655438 P38211 0.945252001285553 0.9294660091400146 0.018592804670333862 0.007729959674179555 58.33784434447017 50.0 0.0 no 464 chrII_245241 1455 essential YBR004C 407 - ACTGTGATTGCCTTATATTT Q|142|H silent|CAG>CAA|Q|142 0 0 0 0 -0.4217294063872289 P38211 0.9570760130882264 0.2152971476316452 44.444451503986606 30.0 0.0 no 465 chrII_245331 1456 essential YBR004C 317 - CAACTCCAACCCTTAAGGCA V|112|L V|112|I G|111|A G|111|E 0 0 0 0 -0.0073652031337347315 P38211 0.9539830088615416 0.9574310183525084 0.9499930143356324 0.9438679814338684 0.2632964551448822 0.3854488730430603 1.0 0.018128547817468643 50.83372592141603 50.0 0.0 no 466 chrII_245417 1459 essential YBR004C 231 - GCGTATTCATGCTCAAATTG A|84|P A|84|T 0 0 0 0 -0.43521341256309576 P38211 0.9573720097541808 0.9523990154266356 0.03964810073375702 0.09707473963499068 43.628009453153375 40.0 0.0 no 467 chrII_245610 1461 essential YBR004C 38 - CCAGTAAATACTGTATTGAA silent|CTG>CTC|L|19 silent|CTG>CTA|L|19 0 0 0 0 -0.22102164642579594 P38211 37.34700744640156 30.0 0.0 no 468 chrII_245610r 1462 essential YBR004C 35 + CCGTTCAATACAGTATTTAC R|13|G R|13|C S|14|* S|14|L 0 0 0 0 -0.3603896530107176 P38211 0.8994590044021606 0.8926740288734436 0.9298099875450134 0.014057648368179798 0.0018848872277885675 1.0 41.55816050153021 35.0 0.0 no 469 chrII_257334 1463 essential YBR011C 622 - CTTCTTGTTCTTAGCTTCAC K|213|N silent|AAG>AAA|K|213 IPP1 Inorganic PyroPhosphatase 287.0 0 1 0 0 -0.17521909951740702 P00817 0.7701560258865356 0.02311696857213974 1.547600030899048 48.637601216421444 40.0 0.0 no 470 chrII_257456r 1466 essential YBR011C 497 + CCCAAAATTGAACGACATTG P|167|R P|167|L P|167|A P|167|S IPP1 Inorganic PyroPhosphatase 287.0 0 0 0 0 1.0506543058445987 P00817 0.9212669730186462 0.9404410123825072 1.0133899450302124 1.0037599802017212 0.4697693884372711 0.2701787054538727 0.8018221259117126 0.9695794582366944 0.8095399737358093 1.1571999788284302 1.496000051498413 1.7755399942398071 39.48142994303811 40.0 0.0 no 471 chrII_257457 1467 essential YBR011C 499 - CTCAATGTCGTTCAATTTTG E|173|Q E|173|K IPP1 Inorganic PyroPhosphatase 287.0 0 1 0 0 -0.9929485048823656 P00817 0.8948709964752197 0.8984220027923584 0.11635205894708632 0.2302784919738769 -0.0508200004696846 0.14368000626564026 40.916033126877494 35.0 0.0 no 472 chrII_257599 1471 essential YBR011C 357 - CCAATTTCCAACACATCAAT G|126|R G|126|S IPP1 Inorganic PyroPhosphatase 287.0 0 1 0 0 0.6762997058442678 P00817 0.5269160270690918 0.8041419982910156 0.001115250401198864 0.007299263495951891 3.725919961929321 2.7484400272369385 42.496300604681785 35.0 0.0 no 473 chrII_257606r 1472 essential YBR011C 347 + CAACGATCCAATTGATGTGT N|117|K silent|AAC>AAT|N|117 IPP1 Inorganic PyroPhosphatase 287.0 0 1 0 0 0.8256969870014403 P00817 0.7773060202598572 0.005349077749997377 -0.5919600129127502 43.11786864557274 40.0 0.0 no 474 chrII_257629 1473 essential YBR011C 327 - TCACCAACTGCCTTAGTTTC G|115|A G|115|D D|116|H D|116|N IPP1 Inorganic PyroPhosphatase 287.0 0 1 0 0 0.6399637105439151 P00817 0.6330710053443909 0.6176580190658569 0.5592300295829773 0.6124439835548401 0.0 0.0 0.0 0.0 9.485540390014648 21.56765937805176 0.28220000863075256 -0.030239999294281006 51.10092508817746 45.0 0.0 no 475 chrII_257423r 1480 essential YBR011C 530 + ATACTTCCCAGGTCTGTTGA Y|178|* silent|TAC>TAT|Y|178 F|179|L silent|TTC>TTT|F|179 IPP1 Inorganic PyroPhosphatase 287.0 0 1 0 0 -0.7501030638932886 P00817 0.923044979572296 1.0 0.8576800227165222 1.4218399524688718 53.40707264147875 45.0 0.0 no 476 chrII_257599r 1483 essential YBR011C 354 + CCAATTGATGTGTTGGAAAT P|119|R P|119|L IPP1 Inorganic PyroPhosphatase 287.0 0 1 0 0 -0.20837258730465247 P00817 0.5530200004577637 0.5475689768791199 0.0 0.0 3.347640037536621 1.930340051651001 40.45025109826247 35.0 0.0 no 477 chrII_296703r 1484 essential YBR029C 1017 + TCATTATTTGCGCCATTTGG S|340|* S|340|L CDS1 CDP-Diacylglycerol Synthase 457.0 0 0 0 0 0.6047582603604278 P38221 0.004164824262261391 48.22802842414643 40.0 0.0 no 478 chrII_297101r 1495 essential YBR029C 619 + TCATCAAAAACGTGCTCAAT I|207|M silent|ATC>ATT|I|207 I|208|M silent|ATC>ATT|I|208 CDS1 CDP-Diacylglycerol Synthase 457.0 0 0 0 0 0.42965873282297 P38221 0.1874617487192154 0.3077409267425537 38.793538334697026 35.0 0.0 no 479 chrII_297157r 1497 essential YBR029C 563 + ATCATTGTGCGTTACTCATA S|189|* S|189|L CDS1 CDP-Diacylglycerol Synthase 457.0 0 0 0 0 -1.2747797506225047 P38221 1.0 45.434645572209895 35.0 0.0 no 480 chrII_297235r 1501 essential YBR029C 485 + CTGCTATTGTCTCTATCTTA C|163|W silent|TGC>TGT|C|163 CDS1 CDP-Diacylglycerol Synthase 457.0 0 0 0 0 0.1830772779215212 P38221 0.0013668633764609694 46.465652938137616 35.0 0.0 no 481 chrII_297338r 1502 essential YBR029C 382 + CCACTATCTATTACTTAGAT T|129|S T|129|I silent|ACC>ACG|T|128 silent|ACC>ACT|T|128 CDS1 CDP-Diacylglycerol Synthase 457.0 0 0 0 0 -1.0358964298754592 P38221 0.022356584668159485 0.07814329117536545 41.22431514881259 30.0 0.0 no 482 chrII_297339r 1503 essential YBR029C 381 + ACCACTATCTATTACTTAGA silent|ACC>ACG|T|128 silent|ACC>ACT|T|128 T|128|S T|128|I CDS1 CDP-Diacylglycerol Synthase 457.0 0 0 0 0 0.07410318528905624 P38221 0.2496809065341949 0.04204310849308968 41.67303538801582 30.0 0.0 no 483 chrII_297485r 1507 essential YBR029C 235 + CCTTAGCATCGGGTCATGCA silent|ACC>ACG|T|79 silent|ACC>ACT|T|79 A|81|G A|81|V CDS1 CDP-Diacylglycerol Synthase 457.0 0 0 0 0 -1.1418572828920803 P38221 0.331213116645813 0.516961932182312 56.434983255206305 55.00000000000001 0.0 no 484 chrII_297495r 1508 essential YBR029C 225 + TTCTTCATCACCTTAGCATC F|76|L silent|TTC>TTT|F|76 F|77|L silent|TTC>TTT|F|77 CDS1 CDP-Diacylglycerol Synthase 457.0 0 0 0 0 0.6136260434203191 P38221 0.015525709837675096 0.4842462539672852 49.284616980711405 40.0 0.0 no 485 chrII_297496r 1510 essential YBR029C 224 + TTTCTTCATCACCTTAGCAT F|76|L silent|TTC>TTT|F|76 F|77|L silent|TTC>TTT|F|77 CDS1 CDP-Diacylglycerol Synthase 457.0 0 0 0 0 -0.7183378386005337 P38221 0.015525709837675096 0.4842462539672852 48.43827045523057 35.0 0.0 no 486 chrII_309474 1519 high_effect YBR036C 820 - TACAGCAGAATTTTCGTTCT V|280|L V|280|I A|279|P A|279|T 0 0 0 0 0.04460831876597909 P35206 0.9539830088615416 0.9574310183525084 0.9573720097541808 0.9523990154266356 0.6579340100288391 0.5941261649131775 0.2869030833244324 0.9552436470985411 43.773811701074926 35.0 0.0 no 487 chrII_309612 1522 high_effect YBR036C 682 - TTCACCCGTGTTAGGGTTGA E|234|Q E|234|K G|233|A G|233|D 0 0 0 0 -2.4154290399504164 P35206 0.956179976463318 0.9475290179252625 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 54.87243092546112 50.0 0.0 yes 488 chrII_309691r 1525 high_effect YBR036C 600 + ATCATGATGAACGCGGTCAT I|201|M silent|ATC>ATT|I|201 0 0 0 0 -1.101412323030636 P35206 0.9598389863967896 0.18504522740840912 46.06669806431938 45.0 0.0 no 489 chrII_309751r 1529 high_effect YBR036C 540 + ACTTTACTATATGGTGTTTG T|181|S T|181|I L|183|V silent|CTA>TTA|L|183 0 0 0 0 -1.4425299596552243 P35206 0.9491789937019348 0.9472420215606691 0.9512209892272948 0.7283363342285156 0.22587162256240845 0.0 40.34478973581969 30.0 0.0 no 490 chrII_309802 1530 high_effect YBR036C 492 - ATCAAAGCAACATCAAATGC L|170|F silent|TTG>TTA|L|170 0 0 0 0 -1.1627571049791392 P35206 0.9587849974632264 0.033285316079854965 37.316064325744655 35.0 0.0 no 491 chrII_309839r 1531 high_effect YBR036C 452 + CGCTGATTTGACTTATAACA A|152|G A|152|V 0 0 0 0 0.0867551753105574 P35206 0.9484469890594482 0.9504740238189696 0.10349415242671968 0.050151508301496506 40.729456038945386 35.0 0.0 no 492 chrII_310119r 1535 high_effect YBR036C 172 + CCTTTATGTATTTTGCTTCG silent|ACC>ACG|T|58 silent|ACC>ACT|T|58 0 0 0 0 0.5193556529204281 P35206 45.53921183776021 35.0 0.0 no 493 chrII_310284 1544 high_effect YBR036C 10 - ACTTGAAAACCAAAGTAGTG S|10|T S|10|N 0 0 0 0 -1.9347049073990656 P35206 0.9512869715690612 0.9536849856376648 0.5464180707931519 0.07836824655532837 36.30246472920891 35.0 0.0 no 494 chrII_311984 1546 essential YBR038W 86 + CGCTAACAGCAACTCTCGGT A|30|G A|30|V N|31|K silent|AAC>AAT|N|31 CHS2 CHitin Synthase 963.0 0 1 0 0 -0.2197805432081203 P14180 0.9484469890594482 0.9504740238189696 0.9439849853515624 0.4299614131450653 0.3578959107398987 0.9877058267593384 50.95051588627632 55.00000000000001 1.0 no 495 chrII_312012r 1548 essential YBR038W 117 - TCCTCCAAACTCTCCTCACT E|45|D silent|GAG>GAA|E|45 D|46|H D|46|N CHS2 CHitin Synthase 963.0 0 1 0 0 -0.1099383912532695 P14180 0.94931298494339 0.9486550092697144 0.956179976463318 0.6256252527236938 0.15100131928920746 0.6078237295150757 55.12690594646159 50.0 1.0 no 496 chrII_312156r 1554 essential YBR038W 261 - GCATACCTGTTCGGAGCAAC A|94|P A|94|T R|92|S silent|AGG>AGA|R|92 CHS2 CHitin Synthase 963.0 0 0 0 0 -0.7191179083133976 P14180 0.9573720097541808 0.9523990154266356 0.9087679982185364 0.2512930631637573 0.5148633122444153 0.9250110387802124 52.11590276531456 55.00000000000001 1.0 no 497 chrII_312216 1557 essential YBR038W 318 + GCTGTCATACATCTAAGTGA A|107|G A|107|V silent|GTC>GTG|V|108 silent|GTC>GTT|V|108 CHS2 CHitin Synthase 963.0 0 1 0 0 -0.1228246744692823 P14180 0.9484469890594482 0.9504740238189696 0.3708068430423737 0.3132448196411133 45.26522191174502 40.0 1.0 no 498 chrII_312391r 1567 essential YBR038W 496 - ATCGTCTGCTTCTGCCAGAG D|172|H D|172|N D|171|H D|171|N CHS2 CHitin Synthase 963.0 0 1 0 0 -0.4519905830541386 P14180 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.3991475105285645 0.5687833428382874 0.1424902379512787 0.5490382909774779 55.929523578923686 55.00000000000001 1.0 no 499 chrII_312541r 1568 essential YBR038W 646 - TCTTCTCTTACTCTCAGAAT R|222|T R|222|K R|221|T R|221|K CHS2 CHitin Synthase 963.0 0 1 0 0 0.8602998105510942 P14180 0.932735025882721 0.955805003643036 0.932735025882721 0.955805003643036 0.27174437046051025 0.7420867681503296 0.20857417583465576 0.4884125292301178 44.726189405379436 35.0 1.0 no 500 chrII_312664r 1575 essential YBR038W 769 - TCTCATTTCCGTAAACTCAG M|262|I M|262|I R|263|T R|263|K CHS2 CHitin Synthase 963.0 0 0 0 0 -0.7865742787943998 P14180 0.9553959965705872 0.9553959965705872 0.932735025882721 0.955805003643036 0.0 0.0 0.11183767765760423 0.04878837615251541 44.455354121156795 40.0 1.0 no 501 chrII_312665r 1576 essential YBR038W 770 - ATCTCATTTCCGTAAACTCA R|263|T R|263|K M|262|I M|262|I CHS2 CHitin Synthase 963.0 0 0 0 0 0.9411293943454516 P14180 0.932735025882721 0.955805003643036 0.9553959965705872 0.9553959965705872 0.11183767765760423 0.04878837615251541 0.0 0.0 44.38999270713305 35.0 1.0 no 502 chrII_312666r 1577 essential YBR038W 771 - TATCTCATTTCCGTAAACTC R|263|T R|263|K M|262|I M|262|I CHS2 CHitin Synthase 963.0 0 0 0 0 0.4211773677878895 P14180 0.932735025882721 0.955805003643036 0.9553959965705872 0.9553959965705872 0.11183767765760423 0.04878837615251541 0.0 0.0 42.544469606829466 35.0 1.0 no 503 chrII_312708r 1579 essential YBR038W 813 - CCTTCTCTCAAAAAATCGTC G|278|R G|278|S E|277|Q E|277|K CHS2 CHitin Synthase 963.0 0 0 0 0 -0.32771562917918473 P14180 0.941340982913971 0.951104998588562 0.956179976463318 0.9475290179252625 0.14050501585006714 0.1216021254658699 0.2517971694469452 0.4867775142192841 41.39443218933753 40.0 1.0 no 504 chrII_312827r 1580 essential YBR038W 932 - CAACATTCTTCATAATGGAG V|317|L V|317|I CHS2 CHitin Synthase 963.0 0 0 0 0 0.1895447943629676 P14180 0.9539830088615416 0.9574310183525084 0.023837272077798843 1.0 38.13722904174068 35.0 1.0 no 505 chrII_312823r 1581 essential YBR038W 928 - ATTCTTCATAATGGAGTGGA K|315|N silent|AAG>AAA|K|315 M|314|I M|314|I CHS2 CHitin Synthase 963.0 0 0 0 0 -0.4053413334651183 P14180 0.9355990290641784 0.9553959965705872 0.9553959965705872 0.013617897406220436 0.10728159546852112 0.10728159546852112 42.47581836635987 35.0 1.0 no 506 chrII_312887r 1585 essential YBR038W 992 - AGACTTTCTTCCAGCCATTG V|337|L V|337|I CHS2 CHitin Synthase 963.0 0 0 0 0 -0.08550243380934355 P14180 0.9539830088615416 0.9574310183525084 0.05648040398955345 0.7257767319679259 51.81657943536169 45.0 1.0 no 507 chrII_312956 1587 essential YBR038W 1058 + TCTCGACTATTTAGCTGCTT silent|CTC>CTG|L|354 silent|CTC>CTT|L|354 L|354|V L|354|F CHS2 CHitin Synthase 963.0 0 0 0 0 -0.0904007745926818 P14180 0.9512209892272948 0.9587849974632264 0.012309673242270948 0.06532922387123108 48.5381104080784 40.0 1.0 no 508 chrII_313000r 1588 essential YBR038W 1105 - ATCACCATTCACAGACGCCT D|375|H D|375|N G|374|A G|374|D CHS2 CHitin Synthase 963.0 0 0 0 0 -0.7409889627666141 P14180 0.9486550092697144 0.956179976463318 0.9499930143356324 0.9446240067481996 0.0072304182685911655 0.021833758801221848 0.4399650990962982 0.9407764673233032 53.32769993469384 50.0 1.0 no 509 chrII_313104r 1590 essential YBR038W 1209 - AGACAAAAAACCAATTGCAC C|409|S C|409|Y CHS2 CHitin Synthase 963.0 0 0 0 0 -0.43220716237847895 P14180 0.9421560168266296 0.9290120005607604 0.0 0.0 35.837279682398965 35.0 1.0 no 510 chrII_313094 1591 essential YBR038W 1196 + GGACATTGTTCCTGTGCAAT D|400|E silent|GAC>GAT|D|400 CHS2 CHitin Synthase 963.0 0 0 0 0 -0.09490021707071858 P14180 0.9532920122146606 0.014554033987224104 50.29444796958399 45.0 1.0 no 511 chrII_313197r 1597 essential YBR038W 1302 - TCAACCAAAGTAACTACAGT D|441|H D|441|N V|440|L V|440|I CHS2 CHitin Synthase 963.0 0 0 0 0 -6.3366180691976135 P14180 0.9486550092697144 0.956179976463318 0.9539830088615416 0.9574310183525084 0.0 0.0 1.0 0.025887278839945797 39.40559147661037 35.0 1.0 yes 512 chrII_314015 1609 essential YBR038W 2117 + ACATTTATTCATTACCTCCA H|707|D H|707|Y CHS2 CHitin Synthase 963.0 0 0 0 0 -0.3793209217274076 P14180 0.9473130106925964 0.9489949941635132 0.08870445191860199 0.1765950322151184 45.457210900441396 30.0 1.0 no 513 chrII_314032r 1610 essential YBR038W 2137 - ACATATAGACAGTATAACCA C|719|S C|719|Y CHS2 CHitin Synthase 963.0 0 0 0 0 -1.6041174537474836 P14180 0.9421560168266296 0.9290120005607604 0.032783668488264084 0.01556970365345478 38.57558901521514 30.0 1.0 no 514 chrII_314056 1612 essential YBR038W 2158 + CCACATATTCTCTAATTTGT T|721|R T|721|I silent|GCC>GCG|A|720 silent|GCC>GCT|A|720 CHS2 CHitin Synthase 963.0 0 0 0 0 0.16164108993316256 P14180 0.9476869702339172 0.9472420215606691 0.03557223454117775 0.7055140137672424 42.38587530252988 30.0 1.0 no 515 chrII_335135r 1614 essential YBR049C 1661 + TCAATTGCATCCAAACTTAT Q|555|E Q|555|* REB1 RNA polymerase I Enhancer Binding protein 810.0 0 0 0 0 0.22876757448165114 P21538 1.0 40.536562340083094 30.0 0.0 no 516 chrII_335229 1615 essential YBR049C 1570 - CCATCTATTTGATGCTCTAT W|530|S W|530|* R|529|T R|529|K REB1 RNA polymerase I Enhancer Binding protein 810.0 0 0 0 0 -2.1684388488159674 P21538 0.0 0.025965722277760502 1.0 46.090157566556904 35.0 0.0 yes 517 chrII_335229r 1616 essential YBR049C 1567 + CCAATAGAGCATCAAATAGA silent|ACC>ACG|T|523 silent|ACC>ACT|T|523 REB1 RNA polymerase I Enhancer Binding protein 810.0 0 0 0 0 -0.8085275745113469 P21538 38.91977951439611 35.0 0.0 no 518 chrII_335421 1622 essential YBR049C 1378 - TCTCATGTGTTTGTAGATAG M|465|I M|465|I R|466|T R|466|K REB1 RNA polymerase I Enhancer Binding protein 810.0 0 0 0 0 -0.16953945117851804 P21538 0.36530178785324097 0.36530178785324097 0.0 0.0 42.393538711427034 35.0 0.0 no 519 chrII_335840r 1627 essential YBR049C 956 + ACTGCAGAAAGACTCTATGC L|320|V silent|CTG>TTG|L|320 Q|321|E Q|321|* REB1 RNA polymerase I Enhancer Binding protein 810.0 0 1 0 0 0.04475452594574575 P21538 0.3024058043956757 1.0 44.10746807951909 45.0 0.0 no 520 chrII_335807r 1628 essential YBR049C 989 + CAACAAATCTAGAAATTATA N|331|K silent|AAC>AAT|N|331 REB1 RNA polymerase I Enhancer Binding protein 810.0 0 0 0 0 0.6042998812060516 P21538 0.9039359092712402 29.0453027617379 20.0 0.0 no 521 chrII_335996r 1631 essential YBR049C 800 + CCAGCAATACTTGAATACTG Q|268|E Q|268|* Q|269|E Q|269|* REB1 RNA polymerase I Enhancer Binding protein 810.0 0 0 0 0 -2.0814898936118977 P21538 0.0838007926940918 0.13661155104637146 41.439480268647905 40.0 0.0 yes 522 chrII_336036 1633 essential YBR049C 763 - AATCGAATCAGCGTCGATAA silent|TCG>TCC|S|260 silent|TCG>TCA|S|260 REB1 RNA polymerase I Enhancer Binding protein 810.0 0 0 0 0 0.18385315786298487 P21538 41.123120760323566 40.0 0.0 no 523 chrII_336059r 1634 essential YBR049C 737 + TCGTGATCAACTGGTCCATA R|247|G R|247|C REB1 RNA polymerase I Enhancer Binding protein 810.0 0 0 0 0 -1.1720977988339834 P21538 0.2621507048606873 0.06799957901239395 48.672699878562696 45.0 0.0 no 524 chrII_336108 1637 essential YBR049C 691 - GTCATCTGCATCACCCAAGG D|237|H D|237|N D|236|H D|236|N REB1 RNA polymerase I Enhancer Binding protein 810.0 0 1 0 0 0.6797794129193844 P21538 0.013830726966261864 0.03638907894492149 0.2153679728507996 0.2728112041950226 54.52167574760392 55.00000000000001 0.0 no 525 chrII_345257r 1651 essential YBR055C 2022 + GGTCAAATTTATCATTCCAT Q|676|E Q|676|* PRP6 Pre-mRNA Processing 899.0 0 0 0 0 1.0067218975782295 P19735 0.9590039849281312 0.0 42.06026414625694 30.0 0.0 no 526 chrII_345345 1652 essential YBR055C 1937 - TAGCCTCTTCATTCAGATCT A|652|P A|652|T E|651|D silent|GAG>GAA|E|651 PRP6 Pre-mRNA Processing 899.0 0 0 0 0 0.8712068678527479 P19735 0.9573720097541808 0.9523990154266356 0.94931298494339 0.02264530025422573 0.02398376725614071 0.30004996061325073 50.50177133316214 40.0 0.0 no 527 chrII_345426r 1655 essential YBR055C 1853 + GCAAACTTTCTCCTCTTTAG Q|619|E Q|619|* T|620|S T|620|I PRP6 Pre-mRNA Processing 899.0 0 0 0 0 -0.2419878255783441 P19735 0.9590039849281312 0.9491789937019348 0.9472420215606691 0.9926260709762572 1.0 0.3528229594230652 46.25238955808896 40.0 0.0 no 528 chrII_345568 1661 essential YBR055C 1714 - TTGCCTAGTATCCCCTTTTT R|577|S silent|AGG>AGA|R|577 R|577|T R|577|K PRP6 Pre-mRNA Processing 899.0 0 0 0 0 0.6547963064117579 P19735 0.9087679982185364 0.932735025882721 0.955805003643036 0.4496019780635834 0.2703066170215607 0.4414321780204773 55.74995080746214 40.0 0.0 no 529 chrII_345608 1662 essential YBR055C 1674 - ACATACATCATTAACAAGCC V|565|L V|565|I M|563|I M|563|I PRP6 Pre-mRNA Processing 899.0 0 0 0 0 0.5483407809206391 P19735 0.9539830088615416 0.9574310183525084 0.9553959965705872 0.9553959965705872 0.10196591168642044 0.05248210579156876 0.6710963249206543 0.6710963249206543 40.65714002997032 35.0 0.0 no 530 chrII_345652 1663 essential YBR055C 1630 - TCGTATATCATCACTATTCT R|550|P R|550|Q PRP6 Pre-mRNA Processing 899.0 0 0 0 0 -0.8952088271296155 P19735 0.9099509716033936 0.949662983417511 0.2408406287431717 0.512633740901947 42.10678551510722 30.0 0.0 no 531 chrII_345803 1666 essential YBR055C 1479 - GCAATTTGTACCTTTGAGTG A|500|P A|500|T PRP6 Pre-mRNA Processing 899.0 0 0 0 0 -0.1855455224554215 P19735 0.9573720097541808 0.9523990154266356 0.20912262797355646 0.5144221186637878 45.58327863306329 40.0 0.0 no 532 chrII_345892 1667 essential YBR055C 1390 - TTCTAATATAGCGTAAACGA E|470|Q E|470|K PRP6 Pre-mRNA Processing 899.0 0 0 0 0 -0.4272133652859038 P19735 0.956179976463318 0.9475290179252625 0.6021245121955872 0.9419623613357544 36.62319184980771 30.0 0.0 no 533 chrII_345961 1671 essential YBR055C 1321 - ACGTTTCAACCATGCTGACA R|447|P R|447|H L|445|F silent|TTG>TTA|L|445 PRP6 Pre-mRNA Processing 899.0 0 0 0 0 0.09913501738391542 P19735 0.9099509716033936 0.9570810198783876 0.9587849974632264 0.11407283693552014 0.394808828830719 0.03437086567282677 48.5424922243235 45.0 0.0 no 534 chrII_346031 1674 essential YBR055C 1251 - AAACTAACTAGTTTATCTAC S|423|T S|423|N PRP6 Pre-mRNA Processing 899.0 0 0 0 0 -0.3534244251624479 P19735 0.9512869715690612 0.9536849856376648 0.5760597586631775 0.4980449378490448 33.396567963194684 25.0 0.0 no 535 chrII_346194r 1676 essential YBR055C 1085 + ACAATTTATTCCACAAAGTA Q|363|E Q|363|* PRP6 Pre-mRNA Processing 899.0 0 0 0 0 0.9829503050007868 P19735 0.9590039849281312 1.0 36.9797868860457 25.0 0.0 no 536 chrII_346263 1678 essential YBR055C 1019 - AACTGACAGCTAGCTTCCAT S|346|T S|346|N V|345|L V|345|I PRP6 Pre-mRNA Processing 899.0 0 0 0 0 0.4536841794414997 P19735 0.9512869715690612 0.9536849856376648 0.9539830088615416 0.9574310183525084 0.3720782101154328 0.4646784365177154 0.3366883397102356 0.7501386404037476 49.88127864519009 45.0 0.0 no 537 chrII_346467 1680 essential YBR055C 815 - GCCAAATATCGGAGCTTCGA W|278|S W|278|* W|278|C W|278|* PRP6 Pre-mRNA Processing 899.0 0 0 0 0 -0.2536424478550505 P19735 0.8858469724655151 0.8858469724655151 0.0 0.0 49.0614973195672 50.0 0.0 no 538 chrII_346537 1681 essential YBR055C 745 - TCTTGCCTTTTCTTCTAATC R|255|T R|255|K A|254|P A|254|T PRP6 Pre-mRNA Processing 899.0 0 0 0 0 -0.7848756039112947 P19735 0.932735025882721 0.955805003643036 0.9573720097541808 0.9523990154266356 0.29287007451057434 0.9515886306762696 0.10776543617248537 0.09822439402341844 47.324752709869024 35.0 0.0 no 539 chrII_346559 1682 essential YBR055C 723 - GCAGAAGCTATCCAACCCTG A|248|P A|248|T PRP6 Pre-mRNA Processing 899.0 0 0 0 0 0.26484125721567936 P19735 0.9573720097541808 0.9523990154266356 0.03479654341936112 0.06795972585678099 52.99472785574255 55.00000000000001 0.0 no 540 chrII_346718 1683 essential YBR055C 564 - TTCGGTTTATTAACCTGTAT silent|CCG>CCC|P|194 silent|CCG>CCA|P|194 PRP6 Pre-mRNA Processing 899.0 0 0 0 0 0.5765779918097023 P19735 42.86191932964607 30.0 0.0 no 541 chrII_347109 1688 essential YBR055C 173 - CATCTTCATCATCTTTCGGT D|64|H D|64|N E|63|Q E|63|K PRP6 Pre-mRNA Processing 899.0 0 0 0 0 0.032424137698867095 P19735 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.007942971773445606 0.0234895832836628 0.1732834279537201 0.20004449784755707 48.8772462517826 40.0 0.0 no 542 chrII_347212 1689 essential YBR055C 70 - TTCTTTTGTTGAAAATCCAG E|30|Q E|30|K PRP6 Pre-mRNA Processing 899.0 0 0 0 0 -0.42312604663513975 P19735 0.956179976463318 0.9475290179252625 0.06733614206314087 0.09903884679079056 38.83186797616953 30.0 0.0 no 543 chrII_361339 1701 essential YBR060C 1156 - TTCGCTTCTTGTCAACTCAG E|392|Q E|392|K S|391|T S|391|N ORC2 Origin Recognition Complex 620.0 0 0 0 0 -1.9640422998330005 P32833 0.16525906324386594 0.023012381047010425 0.3865490555763245 0.9638882279396056 48.575371046324044 45.0 0.0 no 544 chrII_361340 1702 essential YBR060C 1155 - TCGCTTCTTGTCAACTCAGC S|391|T S|391|N E|392|Q E|392|K ORC2 Origin Recognition Complex 620.0 0 0 0 0 0.12903212457872548 P32833 0.3865490555763245 0.9638882279396056 0.16525906324386594 0.023012381047010425 52.1829510802433 50.0 0.0 no 545 chrII_361418 1706 essential YBR060C 1077 - TAACCATTTAAAATAAGGCA G|365|A G|365|D G|365|R G|365|S ORC2 Origin Recognition Complex 620.0 0 0 0 0 -0.9144133671096342 P32833 0.0 0.0 0.0 0.0 34.767429270856034 25.0 0.0 no 546 chrII_361555 1708 essential YBR060C 940 - ACCTACACCATAAAATAATA G|320|R G|320|S G|320|A G|320|D ORC2 Origin Recognition Complex 620.0 0 0 0 0 -2.038048537525403 P32833 0.0 0.0 0.0 0.0 35.64061903690185 25.0 0.0 yes 547 chrII_361589 1711 essential YBR060C 906 - GTCAATTCAAACCAATACTG L|308|F silent|TTG>TTA|L|308 ORC2 Origin Recognition Complex 620.0 0 0 0 0 -1.321244177086702 P32833 0.033823952078819275 38.31081024433507 35.0 0.0 no 548 chrII_361719r 1713 essential YBR060C 773 + GTCAAGGCACACCATGTCAA S|259|* S|259|L ORC2 Origin Recognition Complex 620.0 0 0 0 0 -0.8130057880812218 P32833 0.0 50.554369652693204 50.0 0.0 no 549 chrII_361694 1714 essential YBR060C 801 - AACTCTTCTCTGGTAACGTC E|273|D silent|GAG>GAA|E|273 E|273|Q E|273|K ORC2 Origin Recognition Complex 620.0 0 0 0 0 0.6573550321801752 P32833 0.0 0.0 0.0 46.74107562936956 45.0 0.0 no 550 chrII_361835 1716 essential YBR060C 660 - AGCTTTTTATTTTTCGGTAC K|226|N silent|AAG>AAA|K|226 ORC2 Origin Recognition Complex 620.0 0 0 0 0 0.680618709114714 P32833 0.6107248067855835 43.25562127205643 30.0 0.0 no 551 chrII_361874 1717 essential YBR060C 621 - CTACTCAAGGTTAATTTACC S|213|T S|213|N L|212|F silent|TTG>TTA|L|212 ORC2 Origin Recognition Complex 620.0 0 1 0 0 0.5503307508977613 P32833 0.3548511266708374 1.0 0.0 40.98224153639888 35.0 0.0 no 552 chrII_361875 1718 essential YBR060C 620 - TACTCAAGGTTAATTTACCT S|213|T S|213|N L|212|F silent|TTG>TTA|L|212 ORC2 Origin Recognition Complex 620.0 0 1 0 0 0.20592829261283066 P32833 0.3548511266708374 1.0 0.0 40.982241536398824 30.0 0.0 no 553 chrII_361927 1720 essential YBR060C 568 - ATTCATTATAATTTGCTTTA M|195|I M|195|I ORC2 Origin Recognition Complex 620.0 0 0 0 0 1.0853431147661508 P32833 0.2986412346363068 0.2986412346363068 35.24347571559059 15.0 0.0 no 554 chrII_361928 1721 essential YBR060C 567 - TTCATTATAATTTGCTTTAG M|195|I M|195|I ORC2 Origin Recognition Complex 620.0 0 0 0 0 0.73269681065871 P32833 0.2986412346363068 0.2986412346363068 35.23395051987313 20.0 0.0 no 555 chrII_362027 1723 essential YBR060C 468 - ACAAAATTATCATCAGTTTG V|163|L V|163|I ORC2 Origin Recognition Complex 620.0 0 1 0 0 0.1495359602145424 P32833 0.217211589217186 0.2944988012313843 34.09807009688842 25.0 0.0 no 556 chrII_362053 1724 essential YBR060C 442 - CACATTATCTTCATATGTTG V|154|L V|154|M ORC2 Origin Recognition Complex 620.0 0 0 0 0 -0.08945303979145723 P32833 0.3926315009593964 0.1388934850692749 39.38525294031473 30.0 0.0 no 557 chrII_362406 1736 essential YBR060C 89 - TCAGTTGTCTTTCTCCATGT silent|CTG>CTC|L|36 silent|CTG>CTA|L|36 ORC2 Origin Recognition Complex 620.0 0 0 0 0 -0.41888806217553204 P32833 52.60925152078454 40.0 0.0 no 558 chrII_362420 1737 essential YBR060C 75 - CCATGTGGGTCAACCCTTTT G|32|R G|32|R ORC2 Origin Recognition Complex 620.0 0 0 0 0 -0.031110324125632863 P32833 0.5049790740013123 0.5049790740013123 55.44863151378404 50.0 0.0 no 559 chrII_379381r 1740 essential YBR070C 531 + GAACTTCTTTTGCCCCTGTT L|179|V L|179|F L|180|V L|180|F 0 0 0 0 -0.2105218494208773 P38242 0.9512209892272948 0.9587849974632264 0.9512209892272948 0.9587849974632264 0.28161561489105225 0.3329535722732544 0.6770100593566895 0.4518260657787323 54.71906575506898 45.0 0.0 no 560 chrII_379447 1741 essential YBR070C 468 - CCATTCAATAAAAACAGATG G|163|R G|163|R L|161|F silent|TTG>TTA|L|161 0 0 0 0 -1.774184842551659 P38242 0.941340982913971 0.941340982913971 0.9587849974632264 0.0 0.0 0.15249165892601013 33.37414261722245 30.0 0.0 no 561 chrII_379449 1742 essential YBR070C 466 - ATTCAATAAAAACAGATGAG L|161|F silent|TTG>TTA|L|161 0 0 0 0 -1.035346104773364 P38242 0.9587849974632264 0.15249165892601013 29.51178977145679 25.0 0.0 no 562 chrII_379829 1750 essential YBR070C 86 - TTTCTGTACCTGCTTGAGTG E|35|Q E|35|K 0 0 0 0 1.226016975862883 P38242 0.956179976463318 0.9475290179252625 0.5703847408294678 0.8884639739990234 50.51832517371411 45.0 0.0 no 563 chrII_379875r 1752 essential YBR070C 37 + TATCGACAGCATATGTTATT S|14|W S|14|L T|15|R T|15|I 0 0 0 0 0.2293479777214612 P38242 0.9288619756698608 0.9298099875450134 0.9476869702339172 0.9472420215606691 0.1850137561559677 0.6881391406059265 0.0936279520392418 0.11737766861915587 40.7891343247295 30.0 0.0 no 564 chrII_379902 1753 essential YBR070C 13 - GAGCACCAATGACGCCAAGT silent|GTG>GTC|V|10 silent|GTG>GTA|V|10 V|10|L V|10|M 0 0 0 0 -0.24461923415901016 P38242 0.9539830088615416 0.9587630033493042 0.7610446810722351 0.18956290185451508 51.64899844802704 55.00000000000001 0.0 no 565 chrII_396200 1756 essential YBR079C 2058 - TCTAAGCTTTTAGCTTCGTT D|693|H D|693|N S|691|T S|691|N RPG1 964.0 0 1 0 0 -0.1759473911384521 P38249 0.014503524638712406 0.07753068208694458 0.6281880140304565 0.9464720487594604 46.607147305817186 35.0 0.0 no 566 chrII_396306 1757 essential YBR079C 1952 - TCTTCTTTTCAATTAAGCGA K|657|N silent|AAG>AAA|K|657 K|656|N silent|AAG>AAA|K|656 RPG1 964.0 0 0 0 0 -1.4172913779500342 P38249 0.17479780316352844 0.032253503799438484 41.015920790841214 30.0 0.0 no 567 chrII_396372r 1759 essential YBR079C 1883 + GGTCAGACAACAGCGTATTT silent|GTC>GTG|V|629 silent|GTC>GTT|V|629 RPG1 964.0 0 0 0 0 -0.9109048893135504 P38249 47.16418288834689 45.0 0.0 no 568 chrII_396463 1762 essential YBR079C 1795 - GACACGTTCGTCAACAATCT V|605|L V|605|I R|604|P R|604|H RPG1 964.0 0 0 0 0 0.3613744803692008 P38249 0.3479721248149872 0.21591883897781367 0.0 0.0 45.17339726712004 45.0 0.0 no 569 chrII_396511 1763 essential YBR079C 1747 - CTTCTTAATTAAAGTTTCAC K|588|N silent|AAG>AAA|K|588 RPG1 964.0 0 0 0 0 0.2468730178403787 P38249 0.4366619884967804 34.752298787969444 25.0 0.0 no 570 chrII_396549r 1764 essential YBR079C 1706 + TTTCAACAATGCTTCATACA F|570|L silent|TTC>TTT|F|570 N|571|K silent|AAC>AAT|N|571 RPG1 964.0 0 0 0 0 0.1308178812191035 P38249 0.7184545397758484 0.5726971626281738 40.09095638020853 30.0 0.0 no 571 chrII_396668 1766 essential YBR079C 1590 - TCACCGTCTTCAGTTTCTTG G|536|A G|536|D E|537|Q E|537|K RPG1 964.0 0 0 0 0 -0.23011990025515394 P38249 0.8641721606254578 0.5019321441650391 0.5143052339553833 0.7236883640289307 51.52215109110472 45.0 0.0 no 572 chrII_396888r 1770 essential YBR079C 1367 + TCCGTTAGACTTATCTGCTT P|457|R P|457|L P|457|A P|457|S RPG1 964.0 0 0 0 0 -1.1956839399758714 P38249 0.033706024289131165 0.023799700662493702 0.13039648532867432 0.2665567100048065 2.3384599685668945 1.239016056060791 2.505239963531494 2.7872600555419917 49.43413356557261 40.0 0.0 no 573 chrII_396925 1772 essential YBR079C 1333 - GAGCTTGTATAATTCGGACT K|450|N silent|AAG>AAA|K|450 RPG1 964.0 0 0 0 0 0.8205163658612302 P38249 0.31010618805885315 -0.056639999151229865 44.457149959566955 40.0 0.0 no 574 chrII_396989 1774 essential YBR079C 1269 - CTCATAATGACGTCTCTTAA M|429|I M|429|I RPG1 964.0 0 0 0 0 0.6607919488031977 P38249 0.18793489038944244 0.18793489038944244 0.3972199857234955 0.3972199857234955 40.538688975087716 35.0 0.0 no 575 chrII_397002 1776 essential YBR079C 1256 - CTCTTAAAGGTGCGATGTAT R|425|T R|425|K RPG1 964.0 0 0 0 0 -1.2717637979894127 P38249 0.4913553595542908 0.717452883720398 -0.07891999930143356 0.6893600225448608 43.55247896565596 40.0 0.0 no 576 chrII_397065r 1777 essential YBR079C 1190 + CGACACAGTGAAACAACAGC D|398|E silent|GAC>GAT|D|398 T|399|R T|399|I RPG1 964.0 0 0 0 0 0.9706043760765104 P38249 1.0 0.01025128923356533 0.011467808857560158 0.18073999881744385 -0.7719799876213074 -0.09430000185966493 41.90112872221255 50.0 0.0 no 577 chrII_397326r 1782 essential YBR079C 929 + TTCTACCAATCCAAGAGCCA S|311|C S|311|F T|312|S T|312|I RPG1 964.0 0 1 0 0 -0.18064221885559933 P38249 0.17364880442619324 0.5264009237289429 0.7634363770484924 0.09369157254695892 0.4369199872016907 -1.0716400146484375 -0.35910001397132874 -1.2450400590896606 50.27767327764838 45.0 0.0 no 578 chrII_397440r 1785 essential YBR079C 815 + TGCTCCTAAACCATCTACTT A|273|G A|273|V P|274|A P|274|S RPG1 964.0 0 1 0 0 0.1904476828978953 P38249 0.4389289915561676 0.1473645567893982 0.28111740946769714 0.07777006179094315 48.003921896049796 40.0 0.0 no 579 chrII_397800r 1790 essential YBR079C 455 + TTCATGGTTAAGATTTACTT S|153|* S|153|L RPG1 964.0 0 0 0 0 -0.27899816239409764 P38249 0.011003111489117146 38.44566514680452 25.0 0.0 no 580 chrII_397871 1792 essential YBR079C 387 - ACAGAAATCAGCAAATTTTC V|136|L V|136|I RPG1 964.0 0 0 0 0 0.8199498608376505 P38249 0.08277849853038788 0.09503526240587233 35.679099684670405 30.0 0.0 no 581 chrII_397984 1794 essential YBR079C 274 - ATCAATGAATTTACGTGCAA D|98|H D|98|N RPG1 964.0 0 1 0 0 -0.12470851143727625 P38249 0.049668468534946435 0.1778591275215149 37.853889777818544 30.0 0.0 no 582 chrII_398123 1798 essential YBR079C 135 - ACGACTGGCTCAACAGTTGA V|52|L V|52|M V|51|L V|51|I RPG1 964.0 0 0 0 0 0.13237246375073314 P38249 0.2876810729503632 0.3429131805896759 0.15037454664707184 1.0 48.743789313807156 50.0 0.0 no 583 chrII_398152r 1800 essential YBR079C 103 + TAACTGCCAGAAGAATCCGT T|36|S T|36|I A|37|G A|37|V RPG1 964.0 0 0 0 0 -0.1698840095859501 P38249 0.4743638038635254 0.2147894650697708 0.07093740999698639 0.024172117933630943 46.14935240661139 45.0 0.0 no 584 chrII_398234 1803 essential YBR079C 24 - GCTCTCTTAATGGCATTTTC R|14|T R|14|K A|15|P A|15|T RPG1 964.0 0 0 0 0 0.08452794728700043 P38249 0.0 0.0 0.026102887466549873 0.2231165021657944 47.79070232521207 40.0 0.0 no 585 chrII_399176 1805 essential YBR080C 1695 - GCTGTTTTACCGGACCCTGC A|572|P A|572|T SEC18 SECretory 758.0 0 0 0 0 -1.0396923333133268 P18759 0.007719840388745069 0.006507326383143663 59.61188588304333 60.0 0.0 no 586 chrII_399337 1811 essential YBR080C 1534 - TTCTTCACTAATCCCAAAAG E|518|Q E|518|K E|517|Q E|517|K SEC18 SECretory 758.0 0 0 0 0 -0.3511553509233978 P18759 0.03684860840439797 0.07205293327569963 0.2844835519790649 0.05889439210295677 40.79868343666072 35.0 0.0 no 587 chrII_399349r 1813 essential YBR080C 1519 + ACGATGTTACTCCCGCTTTT N|507|K silent|AAC>AAT|N|507 SEC18 SECretory 758.0 0 0 0 0 0.4975244685415151 P18759 0.8550757765769958 52.34175271791048 45.0 0.0 no 588 chrII_399439 1816 essential YBR080C 1432 - GGCACCTTTCCCGATGTTGA A|484|P A|484|T G|483|A G|483|D SEC18 SECretory 758.0 0 0 0 0 -3.755499377888871 P18759 0.0472935251891613 0.3762462437152863 0.8300546407699585 0.6317688822746277 57.73221459866284 55.00000000000001 0.0 yes 589 chrII_399448r 1817 essential YBR080C 1420 + TCAACAAAACCGTCAACATC I|474|M silent|ATC>ATT|I|474 N|475|K silent|AAC>AAT|N|475 SEC18 SECretory 758.0 0 0 0 0 0.024292377524193887 P18759 0.7473276853561401 0.01204631756991148 39.44494245137031 40.0 0.0 no 590 chrII_399650 1823 essential YBR080C 1221 - ACTTGGACTTCAAATCTACC V|414|L V|414|I SEC18 SECretory 758.0 0 0 0 0 -0.456070719903227 P18759 0.5800954699516296 0.5118798613548279 43.69027233499571 40.0 0.0 no 591 chrII_399688 1824 essential YBR080C 1183 - GTCTATTAAATCTTTACGAT D|401|H D|401|N SEC18 SECretory 758.0 0 0 0 0 -0.8462178772104363 P18759 0.0 0.0 36.46741889950988 25.0 0.0 no 592 chrII_399775 1825 essential YBR080C 1096 - AACTACATTGTCCCCTACAC V|372|L V|372|I V|371|L V|371|I SEC18 SECretory 758.0 0 0 0 0 -2.606384049647267 P18759 0.0 0.0 0.015206024050712584 0.15825532376766205 49.751959028102185 45.0 0.0 yes 593 chrII_399844 1827 essential YBR080C 1027 - ATCGAAAATAATAATATGTA D|349|H D|349|N SEC18 SECretory 758.0 0 0 0 0 -4.688226368020084 P18759 0.0 0.0 27.609869224815498 15.0 0.0 yes 594 chrII_399961 1829 essential YBR080C 910 - TTCTGGACCATTGACGATTT E|310|Q E|310|K SEC18 SECretory 758.0 0 0 0 0 0.2852727229266674 P18759 0.14511772990226746 0.00834547635167837 46.2942517073825 40.0 0.0 no 595 chrII_399962 1830 essential YBR080C 909 - TCTGGACCATTGACGATTTT E|310|Q E|310|K G|308|A G|308|D SEC18 SECretory 758.0 0 0 0 0 -0.17441194114709735 P18759 0.14511772990226746 0.00834547635167837 0.0 0.0 46.294251707382564 40.0 0.0 no 596 chrII_400040r 1832 essential YBR080C 828 + TTGCTATTGTACGGTCCTCC L|278|V silent|CTA>TTA|L|278 SEC18 SECretory 758.0 0 0 0 0 1.188054517828416 P18759 0.0 54.899867994621445 50.0 0.0 no 597 chrII_400082 1833 essential YBR080C 789 - CCCAGTTTTTCTATAACTGA silent|CTG>CTC|L|269 silent|CTG>CTA|L|269 G|270|R G|270|S SEC18 SECretory 758.0 0 0 0 1 -0.7582687117164921 P18759 0.00437537906691432 0.015720628201961517 45.49181956753802 35.0 0.0 no 598 chrII_400312 1838 essential YBR080C 559 - CTCTATCCCAGTTGCAACAG E|193|Q E|193|K silent|GGG>GGC|G|191 silent|GGG>GGA|G|191 SEC18 SECretory 758.0 0 0 0 0 -0.5780720540457838 P18759 0.5801385045051575 0.9189197421073914 0.21797999739646912 0.3333800137042999 51.417079306595156 50.0 0.0 no 599 chrII_400506r 1844 essential YBR080C 362 + CTCATTCAGAGCTAGAGGTA S|122|* S|122|L F|123|L silent|TTC>TTT|F|123 SEC18 SECretory 758.0 0 0 0 0 0.3429400953970132 P18759 0.0366741381585598 0.11184197664260864 -0.7902200222015381 0.12404000014066695 -0.2433599978685379 48.182394873649294 45.0 0.0 no 600 chrII_400593 1847 essential YBR080C 278 - TTGCTTGCACGTCTTGATTT A|99|P A|99|T SEC18 SECretory 758.0 0 0 0 0 0.568225449412777 P18759 0.01710086688399315 0.048340264707803726 3.631247997283936 0.6810399889945984 3.4991800785064697 1.4298800230026243 49.240425412190284 40.0 0.0 no 601 chrII_400662r 1855 essential YBR080C 206 + ACACTCCAACGACATTCCAC H|70|Q silent|CAC>CAT|H|70 H|70|D H|70|Y SEC18 SECretory 758.0 0 0 0 0 0.5508063927370265 P18759 0.6112955212593079 0.5962269902229309 0.11661802232265472 1.289039969444275 2.0471999645233154 1.212440013885498 0.3879199922084808 0.8022599816322327 0.16415999829769135 49.01080249498688 50.0 0.0 no 602 chrII_423927 1864 essential YBR087W 162 + GCATTATTGGAGTCCATATT A|55|G A|55|V RFC5 Replication Factor C 354.0 0 0 0 0 0.41166673121733177 P38251 0.9484469890594482 0.9504740238189696 0.07731904834508896 0.03001127205789089 0.36980000138282776 2.896199941635132 1.631999969482422 3.0085999965667725 46.229336915056756 35.0 1.0 no 603 chrII_424056r 1867 essential YBR087W 294 - TCATTGTTACCCATATCACT D|105|H D|105|N RFC5 Replication Factor C 354.0 0 0 0 0 0.12107806803354755 P38251 0.9486550092697144 0.956179976463318 0.0 0.0 2.1565999984741206 1.003000020980835 47.48195195300559 35.0 1.0 no 604 chrII_424091r 1868 essential YBR087W 329 - CCACTTCTTTCAATAGTTCT V|116|L V|116|M silent|GTG>GTC|V|116 silent|GTG>GTA|V|116 RFC5 Replication Factor C 354.0 0 0 0 0 -0.16615665953340794 P38251 0.9539830088615416 0.9587630033493042 0.15828856825828552 0.3103416860103607 -1.9925999641418457 -1.7619999647140503 -1.5881999731063845 -1.6934000253677368 46.17119880694253 35.0 1.0 no 605 chrII_424217 1870 essential YBR087W 452 + AGCTGCTTTAAGACGTACCA A|152|G A|152|V A|153|G A|153|V RFC5 Replication Factor C 354.0 0 0 0 0 -0.927570051009338 P38251 0.9484469890594482 0.9504740238189696 0.9484469890594482 0.9504740238189696 0.29406288266181946 0.20323364436626434 0.08096345514059068 0.004487023688852787 0.9179999828338624 0.5591999888420105 1.1396000385284424 0.38019999861717213 0.7889999747276306 -0.2409999966621399 1.491000056266785 1.5290000438690186 1.0447334051132202 0.9619333148002625 1.4077000617980957 0.8174999952316284 49.09283073873462 45.0 1.0 no 606 chrII_424302r 1871 essential YBR087W 540 - AACAGACAACGGGATTTGAT silent|CTG>CTC|L|186 silent|CTG>CTA|L|186 C|185|S C|185|Y RFC5 Replication Factor C 354.0 0 0 0 0 1.0969214765170587 P38251 0.9421560168266296 0.9290120005607604 0.03099622018635273 0.0028077526949346066 0.5559999942779541 13.7298002243042 1.305400013923645 8.788800239562987 0.5388000011444092 12.901800155639648 40.72123483409098 40.0 1.0 no 607 chrII_424313r 1872 essential YBR087W 551 - GACAACGAATCAACAGACAA C|190|S C|190|Y R|189|P R|189|H RFC5 Replication Factor C 354.0 0 0 0 0 -0.6789497775681922 P38251 0.9421560168266296 0.9290120005607604 0.9099509716033936 0.9570810198783876 0.0018172342097386718 0.0014874062035232782 0.003352022496983409 0.003248496446758509 0.8203999996185303 10.465200424194336 -0.9142000079154968 0.6538000106811523 1.2874000072479248 8.154399871826174 1.1038000583648682 11.688599586486815 -0.90420001745224 0.6322000026702881 37.11497353130119 40.0 1.0 no 608 chrII_424358 1873 essential YBR087W 593 + TTCAACTATCTTGTCTGATG S|199|* S|199|L T|200|S T|200|I RFC5 Replication Factor C 354.0 0 0 0 0 -1.423782936418906 P38251 0.9298099875450134 0.9491789937019348 0.9472420215606691 0.27002620697021484 0.7402810454368591 0.18436452746391296 -0.5433999896049501 -0.4027999937534332 -0.09300000220537186 41.41447934646328 35.0 1.0 no 609 chrII_424463 1874 essential YBR087W 698 + CCTATTAATGCTTGAATCTA L|234|V silent|CTA>TTA|L|234 RFC5 Replication Factor C 354.0 0 0 0 0 -0.4075039555337793 P38251 0.9512209892272948 0.017472732812166214 2.4059998989105225 1.4988000392913818 2.2137999534606934 40.31971006948596 30.0 1.0 no 610 chrII_424520r 1875 essential YBR087W 758 - TCCAATCTGGTTTTATTATA W|259|S W|259|* W|259|C W|259|* RFC5 Replication Factor C 354.0 0 1 0 0 -1.203362203674316 P38251 0.8858469724655151 0.8858469724655151 0.0 0.0 0.9172000288963318 1.1984000205993652 3.1754000186920166 2.3341999053955083 0.642799973487854 0.8007999658584595 40.86350444961949 25.0 1.0 no 611 chrII_425249r 1879 essential YBR088C 495 + ACAATAAAGTTTGTAGCTGA T|166|R T|166|I POL30 POLymerase 258.0 0 1 0 0 0.6135987733482993 P15873 0.0048138690181076535 0.0011641720775514839 0.5452319979667664 2.078442096710205 37.74211913393009 30.0 0.0 no 612 chrII_425556 1888 essential YBR088C 191 - CCATACCTAACGTAACAGGA M|70|I M|70|I G|69|A G|69|D POL30 POLymerase 258.0 0 0 0 0 -0.9622222715575041 P15873 0.9463379979133606 0.9463379979133606 0.0 0.0 2.7228798866271973 2.7228798866271973 0.17248600721359253 5.22411584854126 7.0911197662353525 17.333080291748047 45.336843239001674 45.0 0.0 no 613 chrII_425691r 1890 essential YBR088C 53 + TTTCAAAGATTGTGTCCAGT F|19|L silent|TTC>TTT|F|19 POL30 POLymerase 258.0 0 0 0 0 -0.35112077741855763 P15873 0.2988917529582977 0.9669319987297058 44.278172751513516 35.0 0.0 no 614 chrII_445697 1895 essential YBR102C 1607 - TCTCTTCCACGCCTTCATCC E|542|Q E|542|K E|542|D silent|GAG>GAA|E|542 EXO84 EXOcyst 753.0 0 1 0 0 -0.7587341314668417 P38261 0.03572611138224602 0.02826472371816635 0.2873304486274719 -0.9568399786949158 -0.9921200275421144 -0.8925200104713441 59.718211256077325 55.00000000000001 0.0 no 615 chrII_445708r 1896 essential YBR102C 1593 + AGGCTTAAATTCCTGGATGA L|533|V L|533|F EXO84 EXOcyst 753.0 0 1 0 0 -1.1656482876689371 P38261 0.029223026707768437 0.1272767186164856 2.103100061416626 0.5907599925994873 2.5744400024414062 3.4812200069427486 45.49901002993278 40.0 0.0 no 616 chrII_445758r 1900 essential YBR102C 1543 + TATCAATGCATTCGAGGCCA S|516|* S|516|L EXO84 EXOcyst 753.0 0 0 0 0 -1.7300652965258216 P38261 0.006588307209312916 49.14256074346729 45.0 0.0 no 617 chrII_445764r 1901 essential YBR102C 1537 + TAACTCTATCAATGCATTCG T|514|S T|514|I L|515|V silent|CTA>TTA|L|515 EXO84 EXOcyst 753.0 0 0 0 0 1.0736355031085414 P38261 0.5361086130142212 0.17188550531864166 0.3722222745418549 40.05478951482985 35.0 0.0 no 618 chrII_445880 1908 essential YBR102C 1424 - TTCTGTTGTTTTCTCTACCT R|481|T R|481|K EXO84 EXOcyst 753.0 0 1 0 0 0.6502148979368646 P38261 0.4518482685089111 1.0 50.07462744973225 35.0 0.0 no 619 chrII_445881 1909 essential YBR102C 1423 - TCTGTTGTTTTCTCTACCTG R|481|T R|481|K EXO84 EXOcyst 753.0 0 1 0 0 0.9933773465862864 P38261 0.4518482685089111 1.0 49.73414366664292 40.0 0.0 no 620 chrII_446126r 1914 essential YBR102C 1175 + AAGCCAGTGCTATCCTTTAA S|393|R silent|AGC>AGT|S|393 Q|394|E Q|394|* EXO84 EXOcyst 753.0 0 0 0 0 -0.4889641368828288 P38261 0.15501615405082705 0.14276596903800964 49.1256459502245 40.0 0.0 no 621 chrII_446323r 1915 essential YBR102C 978 + CAGCTGTTTAAGAACGTTGA L|328|V silent|CTG>TTG|L|328 EXO84 EXOcyst 753.0 0 0 0 0 1.1568147500202897 P38261 0.030246809124946594 42.5056795671577 40.0 0.0 no 622 chrII_446413 1917 essential YBR102C 891 - CCATTTTGTCCTGCTTTCAA G|304|R G|304|R EXO84 EXOcyst 753.0 0 0 0 0 0.5809455138355457 P38261 51.10737054526533 40.0 0.0 no 623 chrII_446413r 1918 essential YBR102C 888 + CCTTTGAAAGCAGGACAAAA P|297|R P|297|L EXO84 EXOcyst 753.0 0 0 0 0 0.8016224080817428 P38261 0.2347065210342407 0.048908498138189316 40.024656734486605 40.0 0.0 no 624 chrII_446597 1923 essential YBR102C 707 - GCTCCAACATAGCAACATTT E|242|Q E|242|K E|242|D silent|GAG>GAA|E|242 EXO84 EXOcyst 753.0 0 0 0 0 -0.43596794052067495 P38261 0.0 0.0 0.0 46.23377434472514 40.0 0.0 no 625 chrII_446600r 1924 essential YBR102C 701 + CGACCTAAATGTTGCTATGT D|235|E silent|GAC>GAT|D|235 L|236|V silent|CTA>TTA|L|236 EXO84 EXOcyst 753.0 0 0 0 0 0.381601912614002 P38261 0.4594176113605499 0.0 44.389819048157904 40.0 0.0 no 626 chrII_446765 1926 essential YBR102C 539 - AATCTTTAGCATTAAAATGC D|186|H D|186|N EXO84 EXOcyst 753.0 0 0 0 0 0.33002168166703433 P38261 0.10753785073757173 0.5453547239303589 34.798045862702 25.0 0.0 no 627 chrII_446997 1934 essential YBR102C 307 - ACTACTATCCACATTATCAT S|109|T S|109|N S|108|T S|108|N EXO84 EXOcyst 753.0 0 0 0 0 0.2829760801989615 P38261 0.3484697341918945 0.562717616558075 0.8296232223510742 0.7234484553337097 42.52168041907925 30.0 0.0 no 628 chrII_447026 1936 essential YBR102C 278 - TCATGTTTGGCATATCAGGT M|99|I M|99|I EXO84 EXOcyst 753.0 0 0 0 0 0.3582759436084512 P38261 48.94895515703604 40.0 0.0 no 629 chrII_447276 1940 essential YBR102C 28 - TACATGCTTCCAATTGTTTC V|16|L V|16|I K|14|N silent|AAG>AAA|K|14 EXO84 EXOcyst 753.0 0 0 0 0 0.07591190641267684 P38261 0.3531945049762726 0.4791882634162903 0.029313737526535988 45.0653191441242 35.0 0.0 no 630 chrII_458033 1942 essential YBR109C 310 - TAGCACGTGTTTCAACTCAG silent|GTG>GTC|V|109 silent|GTG>GTA|V|109 V|109|L V|109|M CMD1 CalMoDulin 147.0 0 0 0 1 -0.7016378397795572 P06787 0.8610550165176392 0.7627170085906982 0.08578291535377502 0.007309391163289547 -1.0333800315856934 -0.2341199964284897 -0.6918533444404602 -0.9194933772087096 46.38076552040906 45.0 0.0 no 631 chrII_458210 1944 essential YBR109C 133 - ATCATTTACTTCTGCTTCAC D|51|H D|51|N CMD1 CalMoDulin 147.0 0 0 0 0 1.0646208692088328 P06787 0.71561598777771 0.8632500171661377 0.03598879650235176 0.09571125358343124 -0.17674000561237335 -0.42017999291419983 45.3356770785507 35.0 0.0 no 632 chrII_458263r 1945 essential YBR109C 77 + CTCTATCTCATCAAGTGAAT S|27|C S|27|F I|28|M silent|ATC>ATT|I|28 CMD1 CalMoDulin 147.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.8617800152764423 P06787 0.9431300163269044 0.931547999382019 0.739205002784729 0.2915603220462799 0.4748216569423676 0.032232683151960366 -0.24247999489307406 0.9657400250434875 0.06911999732255936 2.511199951171875 -0.4232000112533569 -1.4500000476837158 41.30729653378386 35.0 0.0 no 633 chrII_458286r 1946 essential YBR109C 54 + CTCTTTGATAAAGATAACAA silent|CTC>CTG|L|19 silent|CTC>CTT|L|19 CMD1 CalMoDulin 147.0 0 0 0 0 -0.4943167615558182 P06787 32.31657134247939 25.0 0.0 no 634 chrII_458294 1947 essential YBR109C 49 - ATCTTTATCAAAGAGGGCAA D|23|H D|23|N CMD1 CalMoDulin 147.0 0 1 0 0 -1.7533036775477833 P06787 0.6694009900093079 0.8310700058937073 0.002455081092193723 0.1435842216014862 1.1227999925613403 1.5391199588775637 -1.0898000001907349 -1.0388000011444092 40.879211726940405 35.0 0.0 no 635 chrII_459857 1961 essential YBR110W 985 + GCTGTCAAATCGAATTTGTG silent|CGC>CGG|R|329 silent|CGC>CGT|R|329 Q|331|E Q|331|* ALG1 Asparagine-Linked Glycosylation 449.0 0 0 0 0 -0.018651186653742442 P16661 0.9590039849281312 1.0 41.52595925703282 40.0 1.0 no 636 chrII_485603r 1972 essential YBR123C 1066 + TATCTTATCGTTTCACAATG S|357|C S|357|F TFC1 Transcription Factor class C 649.0 0 0 0 0 -0.0042681791638114475 P32367 0.945252001285553 0.9294660091400146 0.013040995225310327 0.006620693486183882 38.966565549031145 30.0 0.0 no 637 chrII_485632 1973 essential YBR123C 1040 - CCAGCGCTATCTTCATAGTA silent|CTG>CTC|L|353 silent|CTG>CTA|L|353 silent|GCG>GCC|A|352 silent|GCG>GCA|A|352 TFC1 Transcription Factor class C 649.0 0 0 0 0 -0.5311778761061822 P32367 51.242109350194596 45.0 0.0 no 638 chrII_485695r 1975 essential YBR123C 974 + CTTCGCTAGACGTCCAATTT F|326|L silent|TTC>TTT|F|326 A|327|G A|327|V TFC1 Transcription Factor class C 649.0 0 0 0 0 1.441116677960019 P32367 0.9387490153312684 0.9484469890594482 0.9504740238189696 0.24893349409103396 0.039109308272600174 0.023075096309185028 48.84605000715374 45.0 0.0 no 639 chrII_485696r 1976 essential YBR123C 973 + TCTTCGCTAGACGTCCAATT silent|CTC>CTG|L|325 silent|CTC>CTT|L|325 F|326|L silent|TTC>TTT|F|326 TFC1 Transcription Factor class C 649.0 0 0 0 0 0.2757141562971813 P32367 0.9387490153312684 0.24893349409103396 49.618646332352114 45.0 0.0 no 640 chrII_485746r 1977 essential YBR123C 923 + CTCTAAATTTTATGAATCGC S|309|C S|309|F TFC1 Transcription Factor class C 649.0 0 0 0 0 0.5246588359086068 P32367 0.945252001285553 0.9294660091400146 0.1690431386232376 0.5376480221748352 36.529517541380244 30.0 0.0 no 641 chrII_489360 2003 high_effect YBR126C 1013 - TGACCACAGATCTTAAATAT V|344|L V|344|I silent|GTG>GTC|V|343 silent|GTG>GTA|V|343 TPS1 Trehalose-6-Phosphate Synthase 495.0 0 0 0 0 -0.5362162646425727 Q00764 0.014561465941369534 0.0827275812625885 38.282803128880225 30.0 0.0 no 642 chrII_489386 2005 high_effect YBR126C 987 - TCTTCCACATCTCCACGACT E|336|Q E|336|K E|335|Q E|335|K TPS1 Trehalose-6-Phosphate Synthase 495.0 0 0 0 0 0.13491917415540078 Q00764 0.0 0.0 0.2686425447463989 0.3041322231292725 54.1621192226591 50.0 0.0 no 643 chrII_489428 2008 high_effect YBR126C 945 - ACAACCTTGCCCCTCCATTC V|322|L V|322|I V|321|L V|321|I TPS1 Trehalose-6-Phosphate Synthase 495.0 0 0 0 0 -0.6297731272702025 Q00764 0.05763036012649536 0.07647281140089035 0.09264721721410753 0.1131763607263565 1.437000036239624 0.4108000099658966 59.25762058627976 55.00000000000001 0.0 no 644 chrII_489454 2011 high_effect YBR126C 919 - CTCGTTCAGAAACACTTCCA E|313|Q E|313|K silent|CTG>CTC|L|311 silent|CTG>CTA|L|311 TPS1 Trehalose-6-Phosphate Synthase 495.0 0 0 0 0 0.0716370885158886 Q00764 0.3245501816272736 0.5546718835830688 46.90784312356806 45.0 0.0 no 645 chrII_489471r 2013 high_effect YBR126C 899 + GCCTCAGAAGTTGCACGCCA P|301|R P|301|L P|301|A P|301|S TPS1 Trehalose-6-Phosphate Synthase 495.0 0 1 0 0 -0.1587022906375244 Q00764 0.003845071420073509 0.05350624397397041 0.022224877029657364 0.0166365597397089 58.405993931039355 60.0 0.0 no 646 chrII_489588r 2016 high_effect YBR126C 782 + GTTCACCGATGGGTTGAAAA F|262|L silent|TTC>TTT|F|262 T|263|S T|263|I TPS1 Trehalose-6-Phosphate Synthase 495.0 0 1 0 0 -1.9237720649503536 Q00764 0.013280550949275494 0.6622122526168823 0.471954733133316 0.22599999606609344 45.19458401569398 45.0 0.0 no 647 chrII_489642 2024 high_effect YBR126C 731 - CTACGTTAACGAATCTGCCC V|250|L V|250|I TPS1 Trehalose-6-Phosphate Synthase 495.0 0 0 0 0 0.2290046817201299 Q00764 0.058829840272665024 0.1972329169511795 47.99202685757183 50.0 0.0 no 648 chrII_489691 2030 high_effect YBR126C 682 - CACGTTAAGCACTCTTTGCA V|234|L V|234|M TPS1 Trehalose-6-Phosphate Synthase 495.0 0 0 0 0 0.2640876158719337 Q00764 1.0 0.17496860027313232 -1.5099999904632568 -1.3944000005722046 48.4561003468554 45.0 0.0 no 649 chrII_489903r 2037 high_effect YBR126C 467 + TTACCATTTGATGTTGGTTC Y|157|* silent|TAC>TAT|Y|157 H|158|D H|158|Y TPS1 Trehalose-6-Phosphate Synthase 495.0 0 0 0 0 0.6285719851691431 Q00764 0.0 0.0 45.22520953963687 35.0 0.0 no 650 chrII_490037r 2043 high_effect YBR126C 333 + CCGTTATTCCATTACCATCC P|112|R P|112|L TPS1 Trehalose-6-Phosphate Synthase 495.0 0 0 0 0 0.4741067119918697 Q00764 0.0031924056820571427 0.002212047576904297 52.61038691862643 45.0 0.0 no 651 chrII_490082r 2044 high_effect YBR126C 288 + ATCGCAGACTTACACTACAA I|97|M silent|ATC>ATT|I|97 A|98|G A|98|V TPS1 Trehalose-6-Phosphate Synthase 495.0 0 0 0 0 -0.5935664263064239 Q00764 0.06988099217414856 0.06515476107597351 0.9656517505645752 -0.633400022983551 1.2350000143051147 -0.8234000205993652 43.40349634107565 40.0 0.0 no 652 chrII_490160 2048 high_effect YBR126C 213 - ACCTGATCCTTCTCATCGTC Q|77|H silent|CAG>CAA|Q|77 V|78|L V|78|M TPS1 Trehalose-6-Phosphate Synthase 495.0 0 0 0 0 0.3495505356607502 Q00764 0.14180365204811096 0.10597336292266846 0.12407374382019044 0.18639999628067014 -0.7731999754905701 -0.9395999908447266 54.612213304637116 50.0 0.0 no 653 chrII_490286r 2058 high_effect YBR126C 84 + ATCACTAAAAACAGCAGTAC I|29|M silent|ATC>ATT|I|29 T|30|S T|30|I TPS1 Trehalose-6-Phosphate Synthase 495.0 0 0 0 0 1.2282355161089082 Q00764 0.07387959957122803 0.546062171459198 0.16691292822360992 -0.025599999353289604 -0.5794000029563904 0.027400000020861626 36.77782754771306 35.0 0.0 no 654 chrII_490346r 2061 high_effect YBR126C 24 + CAACTGACCTCGTCTTCAGG L|10|V silent|CTG>TTG|L|10 TPS1 Trehalose-6-Phosphate Synthase 495.0 0 1 0 0 -0.1560158685566172 Q00764 0.4250779449939728 51.09242830803674 55.00000000000001 0.0 no 655 chrII_490349r 2063 high_effect YBR126C 21 + GCGCAACTGACCTCGTCTTC Q|9|E Q|9|* A|8|G A|8|V TPS1 Trehalose-6-Phosphate Synthase 495.0 0 1 0 0 -0.9911479242508338 Q00764 1.0 0.3603048026561737 0.27030733227729803 55.59587568486478 60.0 0.0 no 656 chrII_491672 2064 high_effect YBR127C 1131 - TTCATCAATCTACTCAACGA M|383|I M|383|I L|382|F silent|TTG>TTA|L|382 VMA2 Vacuolar Membrane Atpase 517.0 0 1 0 0 -0.37763016031117264 P16140 0.9553959965705872 0.9553959965705872 0.9587849974632264 0.015360257588326931 0.015360257588326931 0.0 0.5128200054168701 0.5128200054168701 -0.4137200117111206 40.85595838098948 35.0 0.0 no 657 chrII_491721r 2066 high_effect YBR127C 1079 + TGACCGTCAATTACATAACA D|361|E silent|GAC>GAT|D|361 R|362|G R|362|C VMA2 Vacuolar Membrane Atpase 517.0 0 0 0 0 0.8146917968782956 P16140 0.9532920122146606 0.8994590044021606 0.8926740288734436 0.040557701140642166 0.0034546349197626114 0.0003890534571837634 40.73574185519965 35.0 0.0 no 658 chrII_492176r 2077 high_effect YBR127C 624 + TCCATCGTTTTTGCTGCCAT silent|TCC>TCG|S|209 silent|TCC>TCT|S|209 S|209|C S|209|F VMA2 Vacuolar Membrane Atpase 517.0 0 0 0 0 -0.06801664588520773 P16140 0.945252001285553 0.9294660091400146 0.008067051880061626 0.007008569315075874 55.30990114068783 45.0 0.0 no 659 chrII_492313 2082 high_effect YBR127C 490 - GATCTTTTGACCTCTGGCAA K|169|N silent|AAG>AAA|K|169 VMA2 Vacuolar Membrane Atpase 517.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.6270098438240305 P16140 0.9355990290641784 0.0019459740724414587 50.00928668637261 45.0 0.0 no 660 chrII_492323r 2083 high_effect YBR127C 477 + ACAATGAACTCCATTGCCAG T|160|R T|160|I VMA2 Vacuolar Membrane Atpase 517.0 0 0 0 0 -0.13200994042481487 P16140 0.9476869702339172 0.9472420215606691 0.2872464656829834 0.46201968193054205 46.53143264758296 45.0 0.0 no 661 chrII_492445 2087 high_effect YBR127C 358 - AACTTTAGGACCGTTGTCAA V|126|L V|126|I VMA2 Vacuolar Membrane Atpase 517.0 0 1 0 0 -0.5061293618654635 P16140 0.9539830088615416 0.9574310183525084 0.18081539869308472 0.7137580513954163 -1.2395399808883667 -1.122480034828186 45.184309996517754 40.0 0.0 no 662 chrII_492446 2088 high_effect YBR127C 357 - ACTTTAGGACCGTTGTCAAT V|126|L V|126|I VMA2 Vacuolar Membrane Atpase 517.0 0 1 0 0 0.935922764569235 P16140 0.9539830088615416 0.9574310183525084 0.18081539869308472 0.7137580513954163 -1.2395399808883667 -1.122480034828186 46.699324200689716 40.0 0.0 no 663 chrII_492526 2093 high_effect YBR127C 277 - ACTCTCACCAGTGAATTCCA E|98|D silent|GAG>GAA|E|98 S|99|T S|99|N VMA2 Vacuolar Membrane Atpase 517.0 0 0 0 0 -2.1413174275659017 P16140 0.94931298494339 0.9512869715690612 0.9536849856376648 0.8098247647285461 1.0 0.3296773433685303 50.91923545222097 45.0 0.0 yes 664 chrII_492629 2097 high_effect YBR127C 174 - CCTTGTCTCACGGTTCCATC G|65|R G|65|S R|63|T R|63|K VMA2 Vacuolar Membrane Atpase 517.0 0 0 0 0 -0.5880330342436676 P16140 0.941340982913971 0.951104998588562 0.932735025882721 0.955805003643036 0.001751367351971567 0.012232281267642977 0.08823636174201965 0.05809345096349716 57.136992756072175 55.00000000000001 0.0 no 665 chrII_492731 2103 high_effect YBR127C 72 - ACCGTATTATAGTTCAATCT silent|ACG>ACC|T|30 silent|ACG>ACA|T|30 V|31|L V|31|I VMA2 Vacuolar Membrane Atpase 517.0 0 0 0 0 0.8577310073829377 P16140 0.9539830088615416 0.9574310183525084 0.10314641892910004 0.6020962595939636 -0.31064000725746155 -0.2556400001049042 42.27272979050696 30.0 0.0 no 666 chrII_492757 2105 high_effect YBR127C 46 - CACATTGAAACCTTGTTCGA V|22|L V|22|M VMA2 Vacuolar Membrane Atpase 517.0 0 1 0 0 -1.8585281756060044 P16140 0.9539830088615416 0.9587630033493042 43.383605437654296 40.0 0.0 no 667 chrII_504860 2108 essential YBR135W 6 + CATCACTATCACGCCTTCCA H|4|D H|4|Y H|4|Q silent|CAC>CAT|H|4 0 0 0 0 0.7513138761243457 P20486 0.9473130106925964 0.9489949941635132 0.9588389992713928 -1.908347964286804 0.5079360008239746 0.8809980154037476 53.90905319747975 50.0 1.0 no 668 chrII_504930 2110 essential YBR135W 76 + ATTCCATTCACTATTCTCCG S|27|C S|27|F silent|TCC>TCG|S|27 silent|TCC>TCT|S|27 0 0 0 0 -0.3006386775540933 P20486 0.945252001285553 0.9294660091400146 0.020129509270191196 0.060289215296506875 -0.0033984000328928232 -0.5199918150901794 48.98029262037568 40.0 1.0 no 669 chrII_505082 2115 essential YBR135W 228 + CTCGGCATCACACAGTCTTT silent|CTC>CTG|L|77 silent|CTC>CTT|L|77 silent|GGC>GGG|G|78 silent|GGC>GGT|G|78 0 0 0 0 -0.2535554062836849 P20486 52.59833450229121 50.0 1.0 no 670 chrII_505086 2116 essential YBR135W 232 + GCATCACACAGTCTTTGGGG silent|GGC>GGG|G|78 silent|GGC>GGT|G|78 I|79|M silent|ATC>ATT|I|79 0 0 0 0 0.14297108171494488 P20486 0.9598389863967896 0.002360308077186346 0.16189460456371307 2.0233800411224365 53.593916936531066 55.00000000000001 1.0 no 671 chrII_505160r 2118 essential YBR135W 309 - AGCTCGGCCTCGTAGTTCAG E|109|D silent|GAG>GAA|E|109 E|109|Q E|109|K 0 0 0 0 -0.9542399168371348 P20486 0.94931298494339 0.956179976463318 0.9475290179252625 0.3436258137226105 0.3634181618690491 0.8699841499328613 -0.18406219780445102 0.048949401825666435 -0.3579320013523102 58.61298414107818 60.0 1.0 no 672 chrII_505707 2122 essential YBR136W 39 + GCAATAAAAGACCTGAACTC A|14|G A|14|V MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 0.40952820714740623 P38111 0.9484469890594482 0.9504740238189696 0.3063308596611023 0.2307616472244263 38.503421610258776 40.0 1.0 no 673 chrII_506145 2130 essential YBR136W 477 + GCCTTGACTGAAGTCTTGTT silent|GCC>GCG|A|160 silent|GCC>GCT|A|160 A|160|G A|160|V MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 -1.8562082549746508 P38111 0.9484469890594482 0.9504740238189696 0.4495321810245514 0.4173029065132141 50.648578496983255 45.0 1.0 no 674 chrII_506216 2132 essential YBR136W 548 + TCTTTTATACTGGTTCACTT L|184|V L|184|F MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 0.28558252450101035 P38111 0.9512209892272948 0.9587849974632264 0.4038455784320831 0.0507102832198143 43.92003267415305 30.0 1.0 no 675 chrII_506312r 2134 essential YBR136W 647 - GAACAATCCTGATTAATCGT V|222|L V|222|I MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 -0.1895358590834323 P38111 0.9539830088615416 0.9574310183525084 0.7326083779335022 0.3663277328014374 40.26662875307943 35.0 1.0 no 676 chrII_506350r 2135 essential YBR136W 685 - TTCTAGTGCTGCTAGTTCGC E|235|Q E|235|K MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 0.5379344257430007 P38111 0.956179976463318 0.9475290179252625 0.22083163261413571 0.26964420080184937 54.28033036901428 50.0 1.0 no 677 chrII_506617 2141 essential YBR136W 949 + ACCACTTCCCAATTGACCAG H|318|D H|318|Y D|317|E silent|GAC>GAT|D|317 MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 0.10737663929340917 P38111 0.9473130106925964 0.9489949941635132 0.9532920122146606 0.4738496243953705 1.0 1.0 52.33957169298702 50.0 1.0 no 678 chrII_506821r 2149 essential YBR136W 1156 - CTGCTTATATCGATCATCAA K|391|N silent|AAG>AAA|K|391 MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 0.07635262943472063 P38111 0.9355990290641784 0.13283875584602356 42.190263064304595 35.0 1.0 no 679 chrII_507033 2151 essential YBR136W 1365 + ACATCATGGACTGTAATTCT T|456|R T|456|I S|457|* S|457|L MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 -1.214557225872102 P38111 0.9476869702339172 0.9472420215606691 0.9298099875450134 0.04648177325725555 0.5315555334091187 0.6755168437957764 42.604864761506796 35.0 1.0 no 680 chrII_507064r 2152 essential YBR136W 1399 - AAACTTCTCTGATTCTAGAC K|472|N silent|AAG>AAA|K|472 E|471|D silent|GAG>GAA|E|471 MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 0.31360349419855577 P38111 0.9355990290641784 0.94931298494339 0.5845074653625488 0.5505128502845764 39.600082114844156 35.0 1.0 no 681 chrII_507098 2153 essential YBR136W 1430 + GCCAAATTCCACAAAGGATA P|478|R P|478|L P|478|A P|478|S MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 -0.5730417570245968 P38111 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 43.35224722932117 40.0 1.0 no 682 chrII_507106r 2155 essential YBR136W 1441 - CCAATTATCCATATCCTTTG W|487|S W|487|* MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 0.3015138218965725 P38111 0.8858469724655151 0.9737315177917479 45.267285883493116 35.0 1.0 no 683 chrII_507185 2158 essential YBR136W 1517 + TCCAAATAGACCAGAGGCTG P|507|R P|507|L P|507|A P|507|S MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 -1.4040433285765432 P38111 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.821711540222168 0.5652162432670593 0.7103198170661926 0.6018362641334534 47.69776585854004 50.0 1.0 no 684 chrII_507255r 2160 essential YBR136W 1590 - TCGCTAAATTCATCTATATT S|536|T S|536|N E|537|Q E|537|K MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 1.1228149729363288 P38111 0.9512869715690612 0.9536849856376648 0.956179976463318 0.9475290179252625 0.6354126334190369 0.629427433013916 0.14423121511936188 0.1828106939792633 37.99658261120084 25.0 1.0 no 685 chrII_507330 2162 essential YBR136W 1662 + CAACCTCCAAAACTTACAGA P|556|A P|556|S P|556|R P|556|L MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 -0.3393588777703809 P38111 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.0 0.0 0.0 0.0 42.00745573482953 40.0 1.0 no 686 chrII_507333r 2163 essential YBR136W 1668 - TTTCCATCTGTAAGTTTTGG G|562|A G|562|E G|562|R G|562|R MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 -1.3479533537386508 P38111 0.9499930143356324 0.9438679814338684 0.941340982913971 0.941340982913971 0.7629907131195068 1.0 0.5030431151390076 0.5030431151390076 44.90679215932107 35.0 1.0 no 687 chrII_507336r 2164 essential YBR136W 1671 - CCGTTTCCATCTGTAAGTTT G|564|R G|564|S G|562|A G|562|E MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 0.7943624095386135 P38111 0.941340982913971 0.951104998588562 0.9499930143356324 0.9438679814338684 0.5228163003921509 0.7778831124305725 0.7629907131195068 1.0 49.87515381795033 40.0 1.0 no 688 chrII_507731 2166 essential YBR136W 2063 + ACCTGTATTACTAAGACAGT P|689|R P|689|L P|689|A P|689|S MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 0.4212935286034897 P38111 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 42.77393202268371 35.0 1.0 no 689 chrII_507732 2167 essential YBR136W 2064 + CCTGTATTACTAAGACAGTT P|689|R P|689|L MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 0.16781799031866446 P38111 0.9432820081710817 0.9430609941482544 0.0 0.0 42.583694584161655 35.0 1.0 no 690 chrII_507785 2171 essential YBR136W 2117 + TCAAAATTTAATAGAATTAT Q|707|E Q|707|* MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 0.2630969834555946 P38111 0.9590039849281312 0.7461904287338257 26.095350257885627 10.0 1.0 no 691 chrII_508090r 2175 essential YBR136W 2425 - TTCAGCTAAAGTTTTATAAT E|815|Q E|815|K A|814|P A|814|T MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 0.4951748583371865 P38111 0.956179976463318 0.9475290179252625 0.9573720097541808 0.9523990154266356 0.14010965824127194 0.13222841918468475 0.1491604447364807 0.12179125100374223 34.463986125071976 20.0 1.0 no 692 chrII_508447r 2178 essential YBR136W 2782 - TTGCAAACAAATACTAATCT L|933|F silent|TTG>TTA|L|933 MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 0.4596781719782456 P38111 0.9587849974632264 0.0 33.706020023327945 25.0 1.0 no 693 chrII_508504r 2181 essential YBR136W 2839 - TAACAGATGCCAACATCTAA silent|CTG>CTC|L|952 silent|CTG>CTA|L|952 MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 0.8778612508933902 P38111 40.27198617227521 35.0 1.0 no 694 chrII_508844 2185 essential YBR136W 3176 + CCAAAATTTAGACGATATAG Q|1060|E Q|1060|* MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 0.6499002497503554 P38111 0.9590039849281312 0.23322011530399325 34.134576065478484 30.0 1.0 no 695 chrII_508844r 2186 essential YBR136W 3179 - CCTCTATATCGTCTAAATTT E|1066|Q E|1066|K E|1066|D silent|GAG>GAA|E|1066 MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 0.5613845545006637 P38111 0.956179976463318 0.9475290179252625 0.94931298494339 0.4750128090381622 0.8670973181724548 0.4914273023605346 41.12193680556664 30.0 1.0 no 696 chrII_508931 2187 essential YBR136W 3263 + TTCTGATATAACATTAGTTT S|1089|C S|1089|F MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 0.919620111189294 P38111 0.945252001285553 0.9294660091400146 0.07799701392650604 0.17822256684303284 35.1618779595961 20.0 1.0 no 697 chrII_509017r 2189 essential YBR136W 3352 - ACCAATCATACTGATACATT G|1124|R G|1124|S G|1124|A G|1124|D MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 -2.3010594395005706 P38111 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 40.15033635108557 30.0 1.0 yes 698 chrII_509120 2190 essential YBR136W 3452 + AACTATTAAGTTCTTGATAT T|1152|S T|1152|I MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 0.09279022227272876 P38111 0.9491789937019348 0.9472420215606691 0.057114113122224815 0.042479436844587326 34.050965388878176 20.0 1.0 no 699 chrII_509356 2196 essential YBR136W 3688 + CCTTGTATCTTGCGCAATCA silent|TCC>TCG|S|1230 silent|TCC>TCT|S|1230 MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 0.3759495527113281 P38111 50.64198970257326 45.0 1.0 no 700 chrII_509356r 2197 essential YBR136W 3691 - CCATGATTGCGCAAGATACA W|1237|S W|1237|* MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 0.2546479564469928 P38111 0.8858469724655151 0.6100329756736755 46.470417656455204 45.0 1.0 no 701 chrII_509497 2201 essential YBR136W 3829 + ACGTGTTTTCCTCTTTGATT H|1277|Q silent|CAC>CAT|H|1277 MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 -1.855265048995344 P38111 0.9588389992713928 0.13403791189193726 48.290073406542255 35.0 1.0 no 702 chrII_509915r 2209 essential YBR136W 4250 - TCTGTCGATAGCACTGTTCA Q|1423|H silent|CAG>CAA|Q|1423 R|1422|P R|1422|Q MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 -1.8341349417337949 P38111 0.9570760130882264 0.9099509716033936 0.949662983417511 0.2016199678182602 0.0 0.0 50.100243099411784 45.0 1.0 no 703 chrII_509940 2210 essential YBR136W 4272 + CCTCACGATAAGAACCAAAA H|1426|D H|1426|Y P|1425|R P|1425|L MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 0.29903282033296025 P38111 0.9473130106925964 0.9489949941635132 0.9432820081710817 0.9430609941482544 0.2544446885585785 1.0 0.5294303297996521 0.339756041765213 39.68933744528045 40.0 1.0 no 704 chrII_509940r 2211 essential YBR136W 4275 - CCATTTTGGTTCTTATCGTG G|1432|R G|1432|R MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 -0.11416505767750655 P38111 0.941340982913971 0.941340982913971 0.5060877203941345 0.5060877203941345 47.63194450216423 40.0 1.0 no 705 chrII_510145r 2214 essential YBR136W 4480 - TAGCATCCTGGTTGTAGTTT M|1499|I M|1499|I R|1498|S silent|AGG>AGA|R|1498 MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 -0.05041443967638065 P38111 0.9553959965705872 0.9553959965705872 0.9087679982185364 0.07239531725645065 0.07239531725645065 0.09287499636411667 51.182728384356146 40.0 1.0 no 706 chrII_510157r 2216 essential YBR136W 4492 - ATACATAGACTTTAGCATCC M|1503|I M|1503|I MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 1.0319003030101848 P38111 0.9553959965705872 0.9553959965705872 0.07239531725645065 0.07239531725645065 43.19005625458704 35.0 1.0 no 707 chrII_510213 2217 essential YBR136W 4545 + TCTTCGTTCCATTCTTCAGA S|1516|C S|1516|F S|1517|W S|1517|L MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 0.950932684674418 P38111 0.945252001285553 0.9294660091400146 0.9288619756698608 0.9298099875450134 0.0531100444495678 0.15266767144203186 0.012768710032105446 0.2077409029006958 50.69025290540441 40.0 1.0 no 708 chrII_510242 2218 essential YBR136W 4574 + TTCTTTGTCTCCAGATGTGA S|1526|C S|1526|F MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 0.8911041781195107 P38111 0.945252001285553 0.9294660091400146 0.05400602146983147 0.1023499146103859 49.68310521149215 40.0 1.0 no 709 chrII_510412 2219 essential YBR136W 4744 + TCTCAAACGAGGATCCATTA S|1583|* S|1583|L I|1582|M silent|ATC>ATT|I|1582 MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 -1.2215901769902069 P38111 0.9298099875450134 0.9598389863967896 0.3682426512241364 0.09360579401254654 43.725039708997365 40.0 1.0 no 710 chrII_510734 2221 essential YBR136W 5066 + ATTCTTCACTTTAGCCCAAT F|1690|L silent|TTC>TTT|F|1690 F|1691|L silent|TTC>TTT|F|1691 MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 0.9156690957361304 P38111 0.9387490153312684 0.9387490153312684 0.26326295733451843 0.5858630537986755 48.26159164274771 35.0 1.0 no 711 chrII_510822r 2225 essential YBR136W 5157 - GCAAACTCCAACTCTGCCTG A|1726|P A|1726|T E|1724|D silent|GAG>GAA|E|1724 MEC1 Mitosis Entry Checkpoint 2368.0 0 0 0 0 -0.04651456999803597 P38111 0.9573720097541808 0.9523990154266356 0.94931298494339 0.0 0.0 0.0 51.930315896211994 55.00000000000001 1.0 no 712 chrII_519732 2229 essential YBR140C 6877 - GTCTTCTTCCATCTTTAACT D|2299|H D|2299|N E|2298|Q E|2298|K IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 -0.5625102877266265 P18963 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.021748656406998638 0.06992889195680617 0.265456885099411 0.3968769907951355 47.740791854204424 35.0 0.0 no 713 chrII_519839r 2233 essential YBR140C 6767 + TAACACCACAGGCGTTTCCT N|2257|K silent|AAC>AAT|N|2257 T|2258|S T|2258|I IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 0.22882879956959576 P18963 0.9439849853515624 0.9491789937019348 0.9472420215606691 0.16834582388401031 0.4260193407535553 0.5409300923347473 52.88531344884552 50.0 0.0 no 714 chrII_519924r 2235 essential YBR140C 6682 + ACAAGGTTACCGTATCAAAC Y|2228|* silent|TAC>TAT|Y|2228 IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 0.03571580080892911 P18963 41.553182813731155 40.0 0.0 no 715 chrII_519988r 2238 essential YBR140C 6618 + TGTCCCGTGTCCTTGAAGAT P|2208|A P|2208|S P|2208|R P|2208|L IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 0.4718324246918738 P18963 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.0 0.0 0.0 0.0 54.37991414396902 50.0 0.0 no 716 chrII_520083 2239 essential YBR140C 6526 - ACTCCTACCACTCAATCCTA R|2181|S silent|AGG>AGA|R|2181 S|2182|T S|2182|N IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 1 0 0 0.2776401531507611 P18963 0.9087679982185364 0.9512869715690612 0.9536849856376648 0.4354233145713806 0.8122380375862122 0.37334880232810974 52.159878642857116 45.0 0.0 no 717 chrII_520205r 2244 essential YBR140C 6401 + CAACGTCAACAAATCATTTA N|2135|K silent|AAC>AAT|N|2135 silent|GTC>GTG|V|2136 silent|GTC>GTT|V|2136 IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 0.27989342992103383 P18963 0.9439849853515624 0.0 35.91581253493457 30.0 0.0 no 718 chrII_520317r 2248 essential YBR140C 6289 + TCGATTGTACCACCTTTTAT I|2097|M silent|ATC>ATT|I|2097 IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 0.7244890784479108 P18963 0.9598389863967896 0.19349491596221924 46.74783653558814 35.0 0.0 no 719 chrII_520546 2249 essential YBR140C 6063 - CTCATGAATTCATACAATGA M|2027|I M|2027|I IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 -0.07325338948000439 P18963 0.9553959965705872 0.9553959965705872 0.0 0.0 36.775545008150466 30.0 0.0 no 720 chrII_520683 2255 essential YBR140C 5926 - GCTGAACTCCCCTGGTAATT S|1982|T S|1982|N E|1980|D silent|GAG>GAA|E|1980 IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 1.1078601030633075 P18963 0.9512869715690612 0.9536849856376648 0.94931298494339 0.5275660753250122 0.4732480347156525 1.0 53.661724232162726 50.0 0.0 no 721 chrII_520928r 2257 essential YBR140C 5678 + TCAAAGTTTAGCTAATGGCA Q|1894|E Q|1894|* IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 0.4577077676625993 P18963 0.9590039849281312 0.0 41.867592019271854 35.0 0.0 no 722 chrII_520954 2259 essential YBR140C 5655 - ACTTTAGCTAGTGTAATAAA V|1892|L V|1892|I IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 -0.01509630077373301 P18963 0.9539830088615416 0.9574310183525084 0.04163708910346031 0.40178823471069336 35.83037148258853 25.0 0.0 no 723 chrII_521015r 2260 essential YBR140C 5591 + TGCTTTAGTTAGTCCTGATT A|1865|G A|1865|V IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 -0.4543380886332397 P18963 0.9484469890594482 0.9504740238189696 0.0 0.0 47.91631391953536 35.0 0.0 no 724 chrII_521041r 2262 essential YBR140C 5565 + TTCGTTTTCTTGAGGTTTAT F|1856|L silent|TTC>TTT|F|1856 IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 0.6811369037280933 P18963 0.9387490153312684 0.055640187114477165 44.19704335058747 30.0 0.0 no 725 chrII_521278 2266 essential YBR140C 5331 - TCCACTATCCCTTGCAAAAC silent|GTG>GTC|V|1783 silent|GTG>GTA|V|1783 D|1784|H D|1784|N IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 -0.7144541642329795 P18963 0.9486550092697144 0.956179976463318 0.02940578199923038 0.3579393029212952 48.34701095372743 45.0 0.0 no 726 chrII_521329r 2267 essential YBR140C 5277 + TCACTTTACACTAGATCTAG L|1761|V L|1761|F S|1760|* S|1760|L IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 -0.29555443085781546 P18963 0.9512209892272948 0.9587849974632264 0.9298099875450134 0.025345448404550552 0.024097761139273643 0.008644131943583487 40.58470079226771 35.0 0.0 no 727 chrII_521405 2270 essential YBR140C 5204 - CCCGTTTGATTTCTTGTTTA R|1741|P R|1741|Q silent|CGG>CGC|R|1741 silent|CGG>CGA|R|1741 IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 0.7661884299967341 P18963 0.9099509716033936 0.949662983417511 0.24439047276973724 0.5650275945663452 48.45805349583014 35.0 0.0 no 728 chrII_521591 2272 essential YBR140C 5018 - TATCCATTTCATGTTTCTCA D|1679|H D|1679|N M|1678|I M|1678|I IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 0.4935140807979229 P18963 0.9486550092697144 0.956179976463318 0.9553959965705872 0.9553959965705872 0.12535016238689425 0.4932436048984528 0.13358740508556366 0.13358740508556366 45.83953084701921 30.0 0.0 no 729 chrII_521787r 2275 essential YBR140C 4819 + ATCAGTTTCCAGTTTCATTA Q|1608|E Q|1608|* IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 0.32687086188965336 P18963 0.9590039849281312 0.3310669958591461 46.00031461523202 30.0 0.0 no 730 chrII_522392 2284 essential YBR140C 4217 - GTTCATCTATTTTCAGTCCT E|1412|Q E|1412|K D|1411|H D|1411|N IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 1 0 0 -0.02188679258054349 P18963 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.2768254578113556 0.08069054782390593 0.03921351954340935 0.4813703298568726 49.377546160941726 35.0 0.0 no 731 chrII_522409r 2285 essential YBR140C 4197 + AACTTATTGTTTAACAACCT N|1400|K silent|AAC>AAT|N|1400 IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 0.2496217326618237 P18963 0.9439849853515624 1.0 37.65309998188685 25.0 0.0 no 732 chrII_522607 2289 essential YBR140C 4002 - AAGCTGTCTCCTTCATTATC S|1340|T S|1340|N IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.494427325640861 P18963 0.9512869715690612 0.9536849856376648 48.744319977820616 40.0 0.0 no 733 chrII_522929r 2296 essential YBR140C 3677 + TCAAAAATACGTAGGCGCTT Q|1227|E Q|1227|* IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 -0.8564823324925818 P18963 0.9590039849281312 1.0 41.915911060789256 40.0 0.0 no 734 chrII_523048 2297 essential YBR140C 3561 - CCTACAGCACCAACTAATAA G|1194|R G|1194|R V|1193|L V|1193|I IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 0.22254500077606265 P18963 0.941340982913971 0.941340982913971 0.9539830088615416 0.9574310183525084 0.0 0.0 0.3800044655799866 0.3756527602672577 43.43386366390654 40.0 0.0 no 735 chrII_523631r 2304 essential YBR140C 2975 + TTCTTCTAATCATTCGATTA S|993|C S|993|F S|994|C S|994|F IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 0.7878994977788604 P18963 0.945252001285553 0.9294660091400146 0.945252001285553 0.9294660091400146 0.12321148812770845 0.2240976244211197 0.047030672430992126 0.053874190896749496 38.88690326915923 25.0 0.0 no 736 chrII_523696 2306 essential YBR140C 2913 - TCACTTTGTTGCAATTGCGG S|977|T S|977|N D|978|H D|978|N IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 -0.018909412956489874 P18963 0.9512869715690612 0.9536849856376648 0.9486550092697144 0.956179976463318 0.5771486759185791 0.552523672580719 0.13200023770332334 0.5275235176086426 47.986891467145774 45.0 0.0 no 737 chrII_523922r 2309 essential YBR140C 2684 + TATCACCAATACGCGCACCT I|896|M silent|ATC>ATT|I|896 T|897|S T|897|I IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 1 0 0 0.6246787812085164 P18963 0.9598389863967896 0.9491789937019348 0.9472420215606691 0.1807033121585846 0.8531872630119324 0.19136767089366916 51.30425008360083 50.0 0.0 no 738 chrII_523947 2310 essential YBR140C 2662 - GCTTCCTGAGTTAATTGATA S|894|T S|894|N G|893|A G|893|E IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 1 Series([], Name: modification, dtype: object) 0 0 0 1.8304971968627008 P18963 0.9512869715690612 0.9536849856376648 0.9499930143356324 0.9438679814338684 0.7924114465713501 0.5290486812591553 0.4822891354560852 0.4579735696315765 44.47986673393876 35.0 0.0 no 739 chrII_523948 2311 essential YBR140C 2661 - CTTCCTGAGTTAATTGATAA G|893|A G|893|E G|893|R G|893|R IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 1 0 0 0.088923277251656 P18963 0.9499930143356324 0.9438679814338684 0.941340982913971 0.941340982913971 0.4822891354560852 0.4579735696315765 0.2354496568441391 0.2354496568441391 39.383504311924696 30.0 0.0 no 740 chrII_523951r 2312 essential YBR140C 2655 + TCACCCTTATCAATTAACTC P|887|A P|887|S S|886|* S|886|L IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 -0.8765337964470704 P18963 0.9562489986419678 0.9498909711837769 0.9298099875450134 0.7547193765640259 0.745956540107727 0.26005104184150696 43.42144471898905 35.0 0.0 no 741 chrII_524544 2317 essential YBR140C 2065 - AGCAATATTTGAATCGATTT A|695|P A|695|T IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 0.3893547413077141 P18963 0.9573720097541808 0.9523990154266356 1.0 0.020971640944480896 36.756216463123216 25.0 0.0 no 742 chrII_524739r 2320 essential YBR140C 1867 + CATCCAAAAACCCAAGTATC S|624|C S|624|F silent|TCC>TCG|S|624 silent|TCC>TCT|S|624 IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.5761260935567467 P18963 0.945252001285553 0.9294660091400146 0.03820974379777908 0.03693366050720215 41.877853928072106 40.0 0.0 no 743 chrII_524791 2322 essential YBR140C 1818 - TTCGGATTAATATTCATTAT silent|CCG>CCC|P|612 silent|CCG>CCA|P|612 IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 -0.1421335443287917 P18963 35.43725844724849 20.0 0.0 no 744 chrII_525277r 2330 essential YBR140C 1329 + TCTCCAATCACTTCAACACT P|445|A P|445|S S|444|C S|444|F IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 -0.3029534094362307 P18963 0.9562489986419678 0.9498909711837769 0.945252001285553 0.9294660091400146 0.4009193480014801 0.5611426830291748 0.022913765162229538 0.026882685720920563 46.248346696894366 40.0 0.0 no 745 chrII_525347r 2335 essential YBR140C 1259 + TGCATCGCCTACTTCCCCTA A|421|G A|421|V S|422|W S|422|L IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 0.7228730679854319 P18963 0.9484469890594482 0.9504740238189696 0.9288619756698608 0.9298099875450134 0.5675479173660278 0.2981207072734833 0.021303277462720868 0.20505273342132568 60.615993083549434 55.00000000000001 0.0 no 746 chrII_525376r 2336 essential YBR140C 1230 + TCTCCGTCTCAGTTTTCTAC P|412|A P|412|S S|411|C S|411|F IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 0.29363316473990364 P18963 0.9562489986419678 0.9498909711837769 0.945252001285553 0.9294660091400146 0.21693728864192965 0.41865599155426025 0.047767523676157005 0.08022055774927139 52.51886444009529 45.0 0.0 no 747 chrII_525714 2338 essential YBR140C 895 - TATCCAAAATAAAAAAGCTT W|304|C W|304|* W|304|S W|304|* IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 -0.16318565767435944 P18963 0.8858469724655151 0.8858469724655151 0.006902242079377174 0.011238093487918377 30.466505953165377 20.0 0.0 no 748 chrII_525770 2340 essential YBR140C 839 - TCCTCTTCATGTAACTTGAC R|286|T R|286|K R|286|S silent|AGG>AGA|R|286 IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 0.33196691575472004 P18963 0.932735025882721 0.955805003643036 0.9087679982185364 0.01981351152062416 1.0 0.01560390926897526 45.900410372323286 40.0 0.0 no 749 chrII_525867 2343 essential YBR140C 742 - TACTACGCCCAATTCGGTTG V|254|L V|254|I V|253|L V|253|I IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 -0.6551505656878125 P18963 0.9539830088615416 0.9574310183525084 0.9539830088615416 0.9574310183525084 0.06874747574329376 0.3596319258213043 0.0760372206568718 0.8839195966720581 50.30274896045768 50.0 0.0 no 750 chrII_525874r 2344 essential YBR140C 732 + TCACACACCTCAACCGAATT H|246|D H|246|Y S|245|* S|245|L IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 0.03425798362225427 P18963 0.9473130106925964 0.9489949941635132 0.9298099875450134 0.5020191073417664 0.11531243473291394 0.05536826327443123 47.11690102466724 45.0 0.0 no 751 chrII_525875r 2345 essential YBR140C 731 + ATCACACACCTCAACCGAAT S|245|* S|245|L H|246|D H|246|Y IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 -1.150593914585325 P18963 0.9298099875450134 0.9473130106925964 0.9489949941635132 0.05536826327443123 0.5020191073417664 0.11531243473291394 46.86856626021154 45.0 0.0 no 752 chrII_526172r 2347 essential YBR140C 434 + CACGAGAATCAATCCAGCTT T|146|R T|146|M IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 0 0 0 -0.4449649762856325 P18963 0.9476869702339172 0.9502379894256592 0.19657573103904724 0.16801796853542328 45.792098634837025 45.0 0.0 no 753 chrII_526408r 2350 essential YBR140C 198 + CCGATTATCGAAAACACATT P|67|R P|67|L IRA1 Inhibitory Regulator of the RAS-cAMP pathway 3092.0 0 1 0 0 -0.4541582746004693 P18963 0.9432820081710817 0.9430609941482544 0.3799982368946075 0.6278070211410522 38.81120519265431 35.0 0.0 no 754 chrII_528725r 2357 essential YBR142W 411 - TCCTCATCCACATCCTCACT E|143|D silent|GAG>GAA|E|143 D|144|H D|144|N MAK5 MAintenance of Killer 773.0 0 1 0 0 0.09698078539396984 P38112 0.4865479171276093 0.12008380144834517 0.4825174510478973 57.50983775205748 50.0 1.0 no 755 chrII_528917 2359 essential YBR142W 600 + TCTATTCCAGTTATTATGCA S|201|C S|201|F P|203|A P|203|S MAK5 MAintenance of Killer 773.0 0 0 0 0 0.4347528655482921 P38112 0.15183553099632266 0.06329977512359619 0.0 0.0 44.84029044676305 30.0 1.0 no 756 chrII_529121r 2364 essential YBR142W 807 - TACTGAGATTTCGCTAGAAC Q|275|H silent|CAG>CAA|Q|275 MAK5 MAintenance of Killer 773.0 0 0 0 0 -0.4496296344911385 P38112 0.11533278226852416 41.294183526633724 40.0 1.0 no 757 chrII_529228 2366 essential YBR142W 911 + CGCAACACCAGGTAGATTTT A|305|G A|305|V T|306|R T|306|I MAK5 MAintenance of Killer 773.0 0 0 0 0 0.4818770154310994 P38112 0.04375578090548515 0.19301797449588776 0.0 0.0 47.59836289406201 45.0 1.0 no 758 chrII_529309r 2367 essential YBR142W 995 - ACAGCCTATCAGCCTCATCA silent|CTG>CTC|L|338 silent|CTG>CTA|L|338 R|337|S silent|AGG>AGA|R|337 MAK5 MAintenance of Killer 773.0 0 0 0 0 -0.12283407323292912 P38112 0.0 56.45467773514065 50.0 1.0 no 759 chrII_529410r 2369 essential YBR142W 1096 - CCAAATTTTGCTACTGCCCT W|372|S W|372|* MAK5 MAintenance of Killer 773.0 0 0 0 0 1.1829794854637496 P38112 0.0490896999835968 51.865446702328136 45.0 1.0 no 760 chrII_529461r 2370 essential YBR142W 1147 - TAGCTTATCAAACAAGTCGA K|388|N silent|AAG>AAA|K|388 MAK5 MAintenance of Killer 773.0 0 0 0 0 0.6057618992023924 P38112 0.0 39.61842195651929 35.0 1.0 no 761 chrII_529483 2372 essential YBR142W 1166 + ATCTTCTTCCCGTCAAGTTA S|390|C S|390|F S|391|C S|391|F MAK5 MAintenance of Killer 773.0 0 0 0 0 0.14160890658765102 P38112 0.04715761542320252 0.05433814972639084 0.03558916226029396 0.03706202656030655 51.018325145465326 40.0 1.0 no 762 chrII_529491r 2373 essential YBR142W 1177 - CCTTCTATCCTTAACTTGAC R|399|T R|399|K R|398|T R|398|K MAK5 MAintenance of Killer 773.0 0 0 0 0 -1.634213683170623 P38112 0.6333982348442078 0.9986358880996704 0.5755042433738708 1.0 46.40036996761796 40.0 1.0 no 763 chrII_529492r 2374 essential YBR142W 1178 - ACCTTCTATCCTTAACTTGA R|399|T R|399|K R|399|S silent|AGG>AGA|R|399 MAK5 MAintenance of Killer 773.0 0 0 0 0 1.4599977518658336 P38112 0.6333982348442078 0.9986358880996704 0.7588576078414917 46.40036996761796 35.0 1.0 no 764 chrII_529685 2375 essential YBR142W 1368 + TACTTTTTAACCATGTTCCC Y|457|* silent|TAC>TAT|Y|457 MAK5 MAintenance of Killer 773.0 0 0 0 0 -0.3163259850371101 P38112 46.908677552367756 35.0 1.0 no 765 chrII_529818 2376 essential YBR142W 1501 + ACCGTTTGAAAAGCTTAGAA R|502|G R|502|C N|501|K silent|AAC>AAT|N|501 MAK5 MAintenance of Killer 773.0 0 0 0 0 -2.62881876177514 P38112 0.0 0.0 1.0 39.893975001417225 35.0 1.0 yes 766 chrII_529819r 2377 essential YBR142W 1505 - ACCTTTCTAAGCTTTTCAAA R|508|T R|508|K R|508|S silent|AGG>AGA|R|508 MAK5 MAintenance of Killer 773.0 0 0 0 0 1.0914612005040272 P38112 0.07726290076971054 0.9970516562461852 0.06912799924612045 42.20066158589276 30.0 1.0 no 767 chrII_529867 2378 essential YBR142W 1550 + AACAATAAATCATTCGAATC T|518|R T|518|I MAK5 MAintenance of Killer 773.0 0 0 0 0 -0.7413696817508202 P38112 31.423137831127967 25.0 1.0 no 768 chrII_529934 2381 essential YBR142W 1617 + GCTAGAGGTTTAGATATTCC A|540|G A|540|V MAK5 MAintenance of Killer 773.0 0 0 0 0 -1.3960862728354162 P38112 0.0 0.0 46.29422811217597 40.0 1.0 no 769 chrII_531248r 2383 essential YBR143C 912 + ACTTTAAAGGCATTGGATTT T|305|S T|305|I SUP45 SUPpressor 437.0 0 0 0 0 0.7173245156885852 P12385 0.9491789937019348 0.9472420215606691 0.09605703502893448 0.0023136085364967585 40.308725495919475 30.0 0.0 no 770 chrII_531281r 2384 essential YBR143C 879 + GACACTGGTAAATTCTGTTA D|294|E silent|GAC>GAT|D|294 T|295|S T|295|I SUP45 SUPpressor 437.0 0 0 0 0 -0.23565418868179466 P12385 0.9532920122146606 0.9491789937019348 0.9472420215606691 0.05029336363077164 0.42666926980018616 0.006733004469424486 41.02485368084251 35.0 0.0 no 771 chrII_531285 2385 essential YBR143C 878 - AACAGAATTTACCAGTGTCC C|299|S C|299|Y SUP45 SUPpressor 437.0 0 0 0 0 -1.371240154503063 P12385 0.9421560168266296 0.9290120005607604 0.009608255699276924 0.002123802900314331 0.5856000185012817 -0.06319999694824219 44.711197502767675 40.0 0.0 no 772 chrII_531343 2388 essential YBR143C 820 - TTCTTGAACATACTTGACAT E|280|Q E|280|K SUP45 SUPpressor 437.0 0 0 0 0 -0.6340592046862211 P12385 0.956179976463318 0.9475290179252625 0.00724364398047328 0.00861242413520813 38.982523233266996 30.0 0.0 no 773 chrII_531413r 2391 essential YBR143C 747 + ATCGTGGATGTTTCTTATGG I|250|M silent|ATC>ATT|I|250 SUP45 SUPpressor 437.0 0 0 0 0 0.15284297033097838 P12385 0.9598389863967896 0.03319152444601059 -0.32260000705718994 45.52829243179861 40.0 0.0 no 774 chrII_531483r 2393 essential YBR143C 677 + TGCTGACTTTAAGACCGATT A|227|G A|227|V D|228|E silent|GAC>GAT|D|228 SUP45 SUPpressor 437.0 0 0 0 0 -0.8561681999224987 P12385 0.9484469890594482 0.9504740238189696 0.9532920122146606 0.0851292684674263 0.03153633698821068 0.09945745021104813 -1.8400000333786009 1.8702000379562376 44.851333196775215 40.0 0.0 no 775 chrII_531650r 2396 essential YBR143C 510 + GTCGATCTGCCAAAAAAGCA silent|GTC>GTG|V|171 silent|GTC>GTT|V|171 L|173|V silent|CTG>TTG|L|173 SUP45 SUPpressor 437.0 0 0 0 1 -0.9570211114121884 P12385 0.9512209892272948 0.0 1.8628000020980835 44.229519636972505 45.0 0.0 no 776 chrII_531716r 2398 essential YBR143C 444 + GACGGTCAAGGTACTTTGTT D|149|E silent|GAC>GAT|D|149 Q|151|E Q|151|* SUP45 SUPpressor 437.0 0 0 0 0 -1.4101234073628397 P12385 0.9532920122146606 0.9590039849281312 0.02592424303293228 0.06110198050737381 47.89959885705042 45.0 0.0 no 777 chrII_531899r 2400 essential YBR143C 261 + AACGGTTTAGTTTTATATTG N|88|K silent|AAC>AAT|N|88 SUP45 SUPpressor 437.0 0 0 0 0 0.6246163474212051 P12385 0.9439849853515624 0.043276164680719376 36.77832592397465 25.0 0.0 no 778 chrII_531997r 2402 essential YBR143C 163 + CTGCCTCGAATATTAAATCT A|56|G A|56|V silent|GCC>GCG|A|56 silent|GCC>GCT|A|56 SUP45 SUPpressor 437.0 0 1 0 0 0.008182521241020091 P12385 0.9484469890594482 0.9504740238189696 0.0 0.0 2.0004000663757324 1.1411999464035034 41.427662873377976 35.0 0.0 no 779 chrII_532131r 2405 essential YBR143C 29 + GATCTGGAAGGTCAAGAAGT I|11|M silent|ATC>ATT|I|11 SUP45 SUPpressor 437.0 0 1 0 0 0.2507525575789255 P12385 0.9598389863967896 0.3847889304161072 0.08560000360012054 43.37645700429101 45.0 0.0 no 780 chrII_546495r 2411 essential YBR152W 122 - TTTCGCCGCCCAAATCACTA E|47|Q E|47|K G|46|A G|46|D SPP381 Suppressor of PrP38-1 291.0 0 1 0 0 -0.06122997271374835 P38282 0.956179976463318 0.9475290179252625 0.9499930143356324 0.9446240067481996 53.141288515243 50.0 1.0 no 781 chrII_546586r 2413 essential YBR152W 213 - TCGGGACTCTCATCACTTTC E|78|Q E|78|K S|76|T S|76|N SPP381 Suppressor of PrP38-1 291.0 0 0 0 0 0.7106548048444358 P38282 0.956179976463318 0.9475290179252625 0.9512869715690612 0.9536849856376648 0.2633752822875977 0.25032705068588257 51.21035269279167 50.0 1.0 no 782 chrII_546667r 2414 essential YBR152W 294 - TTCTTCATAAATAATGGCCT K|104|N silent|AAG>AAA|K|104 M|103|I M|103|I SPP381 Suppressor of PrP38-1 291.0 0 0 0 0 -1.0315481393276404 P38282 0.9355990290641784 0.9553959965705872 0.9553959965705872 0.1638663411140442 0.2738960087299347 0.2738960087299347 41.03643742875488 30.0 1.0 no 783 chrII_546731r 2418 essential YBR152W 358 - TGCGTCATCTTGGGCATTCC A|126|P A|126|T D|125|H D|125|N SPP381 Suppressor of PrP38-1 291.0 0 0 0 0 -0.4489278870687395 P38282 0.9573720097541808 0.9523990154266356 0.9486550092697144 0.956179976463318 0.27465566992759705 0.6050859689712524 0.02626917883753777 0.09216631948947906 57.09815861444394 55.00000000000001 1.0 no 784 chrII_546792 2422 essential YBR152W 416 + CATCGACAAAGCTAATCAAG I|140|M silent|ATC>ATT|I|140 D|141|E silent|GAC>GAT|D|141 SPP381 Suppressor of PrP38-1 291.0 0 0 0 0 -0.7832873664277306 P38282 0.9598389863967896 0.9532920122146606 0.02450714260339737 1.0 37.67748403358951 40.0 1.0 no 785 chrII_547755r 2435 essential YBR153W 298 - ATCTATTATTATTGGCCTTG D|106|H D|106|N 0 0 0 0 -0.9901950808439864 P33312 0.9486550092697144 0.956179976463318 0.0 0.0 6.441740036010742 1.2329800128936768 43.069218720976785 30.0 1.0 no 786 chrII_547763r 2436 essential YBR153W 306 - TGCTTTGTATCTATTATTAT K|108|N silent|AAG>AAA|K|108 0 0 0 0 0.4748315036166209 P33312 0.9355990290641784 0.44494783878326416 0.01624000072479248 0.4798400104045868 38.47293012845114 20.0 1.0 no 787 chrII_547781 2438 essential YBR153W 321 + AAGCAAAAGTGGCGATTTGA Q|109|E Q|109|* 0 0 0 0 0.970824731235007 P33312 0.9590039849281312 0.2806819081306457 0.8694800138473511 41.266471159270615 40.0 1.0 no 788 chrII_547817 2439 essential YBR153W 357 + GAACTTTTTATTAAACGACA L|121|V L|121|F 0 0 0 0 0.619241581126787 P33312 0.9512209892272948 0.9587849974632264 0.7261819839477539 0.13164004683494568 1.9035799503326416 0.9128000140190125 1.3570799827575684 0.7467799782752991 34.0311410864278 25.0 1.0 no 789 chrII_548636 2443 essential YBR154C 354 - GGCACCAATTTCATTGCACT silent|GTG>GTC|V|124 silent|GTG>GTA|V|124 V|124|L V|124|M RPB5 RNA Polymerase B 215.0 0 0 0 0 -0.09557759346495244 P20434 0.5851101875305176 0.2757128179073334 -0.3125199973583221 -0.05385399982333183 -1.3968000411987305 -1.2790000438690186 50.82325166752247 45.0 0.0 no 790 chrII_548640r 2444 essential YBR154C 347 + TACACCAAGTGCAATGAAAT T|117|R T|117|I P|118|A P|118|S RPB5 RNA Polymerase B 215.0 0 0 0 0 -0.5524091368448809 P20434 0.002930542454123497 0.003353327512741089 0.1060635894536972 0.4392079114913941 0.9360520243644714 0.3792159855365753 1.3309880495071411 1.7852200269699097 39.2473353688153 35.0 0.0 no 791 chrII_548728 2445 essential YBR154C 262 - CTTCATTGTCTTTACACCAA M|93|I M|93|I RPB5 RNA Polymerase B 215.0 0 0 0 0 0.055706155954522996 P20434 0.8398217558860779 0.8398217558860779 3.426245927810669 3.426245927810669 2.9739999771118164 2.9739999771118164 44.992859349370185 35.0 0.0 no 792 chrII_548758 2446 essential YBR154C 232 - ATCACAAAATTCTACCCATA D|84|H D|84|N C|83|S C|83|Y RPB5 RNA Polymerase B 215.0 0 0 0 0 -0.0835417722480844 P20434 0.06418346613645554 0.2464582473039627 0.6986480355262756 0.26245591044425964 0.3586199879646301 -0.3504000008106232 0.8508999943733215 13.998372077941895 -0.3607999980449677 0.819599986076355 40.46645238171857 30.0 0.0 no 793 chrII_548826r 2450 essential YBR154C 161 + ACGTAAAATGATGTCCTTCC R|55|G R|55|C RPB5 RNA Polymerase B 215.0 0 0 0 0 -0.4438345715732718 P20434 0.006500072777271271 0.0008612190722487867 2.104700088500977 1.53056001663208 43.81321162392669 40.0 0.0 no 794 chrII_549849r 2453 essential YBR155W 81 - TCTTTAAATTCGGATAGTTG D|34|H D|34|N CNS1 CyclophiliN Seven suppressor 385.0 0 0 0 0 -2.3682058535214963 P33313 0.9486550092697144 0.956179976463318 0.2300367504358292 1.0 37.43861741615433 30.0 1.0 yes 795 chrII_549851r 2454 essential YBR155W 83 - TATCTTTAAATTCGGATAGT D|34|H D|34|N CNS1 CyclophiliN Seven suppressor 385.0 0 0 0 0 -0.6138870594052007 P33313 0.9486550092697144 0.956179976463318 0.2300367504358292 1.0 36.62454878980765 25.0 1.0 no 796 chrII_549925r 2455 essential YBR155W 157 - ACCGTCTGTTTCATCCAACT G|59|R G|59|S G|59|A G|59|D CNS1 CyclophiliN Seven suppressor 385.0 0 1 0 0 0.9150825475776196 P33313 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.1043967455625534 0.22960832715034485 0.24199800193309784 0.7082571387290955 52.20682951355491 45.0 1.0 no 797 chrII_549912r 2461 essential YBR155W 144 - TCCAACTTGGTCATGAAAAA L|54|F silent|TTG>TTA|L|54 D|55|H D|55|N CNS1 CyclophiliN Seven suppressor 385.0 0 1 0 0 -2.6136870995759294 P33313 0.9587849974632264 0.9486550092697144 0.956179976463318 0.09453492611646652 0.02034253440797329 0.05484316125512123 39.2358305328417 35.0 1.0 yes 798 chrII_550329r 2466 essential YBR155W 561 - TTCAAAATTGATTTGTTCTC L|193|F silent|TTG>TTA|L|193 CNS1 CyclophiliN Seven suppressor 385.0 0 0 0 0 0.6797025023009979 P33313 0.9587849974632264 0.08087756484746933 35.737361699107794 25.0 1.0 no 799 chrII_550328r 2467 essential YBR155W 560 - TCAAAATTGATTTGTTCTCT L|193|F silent|TTG>TTA|L|193 CNS1 CyclophiliN Seven suppressor 385.0 0 0 0 0 0.20683047979273333 P33313 0.9587849974632264 0.08087756484746933 37.32072352380658 25.0 1.0 no 800 chrII_550500 2468 essential YBR155W 729 + CCAGTAGAGTTACTTAATGA P|244|R P|244|L CNS1 CyclophiliN Seven suppressor 385.0 0 0 0 0 1.0917373068421352 P33313 0.9432820081710817 0.9430609941482544 0.6295028328895569 0.219571515917778 41.553513111011455 35.0 1.0 no 801 chrII_550500r 2470 essential YBR155W 732 - CCCTCATTAAGTAACTCTAC E|250|D silent|GAG>GAA|E|250 G|251|R G|251|S CNS1 CyclophiliN Seven suppressor 385.0 0 0 0 0 0.1313006845886763 P33313 0.94931298494339 0.941340982913971 0.951104998588562 0.646330714225769 0.5311618447303772 0.7602395415306091 44.68411172985793 40.0 1.0 no 802 chrII_550589r 2471 essential YBR155W 821 - AATCAAATTCATCTTGCGTG D|280|H D|280|N CNS1 CyclophiliN Seven suppressor 385.0 0 0 0 0 0.10714204846230684 P33313 0.9486550092697144 0.956179976463318 0.0 0.0 40.188075151135884 35.0 1.0 no 803 chrII_560381 2477 essential YBR160W 303 + ATTCCAAAGGACCAACCGTT P|103|A P|103|S P|103|R P|103|L CDC28 Cell Division Cycle 298.0 0 0 0 0 0.4418427182760292 P00546 0.7679832577705383 0.7533938884735107 0.5924694538116455 0.3226853609085083 48.182344078217966 45.0 1.0 no 804 chrII_560583 2480 essential YBR160W 505 + CACATGAAATTGTTACTCTA H|170|D H|170|Y CDC28 Cell Division Cycle 298.0 0 1 0 0 -0.04466923050705995 P00546 0.026891585439443588 0.07457537204027176 0.1162400022149086 -0.58160001039505 0.030906667932868007 -0.453443318605423 37.603415205110934 30.0 1.0 no 805 chrII_560615r 2483 essential YBR160W 540 - TTTCCACCCAGTAATACCTC G|186|A G|186|E G|186|R G|186|R CDC28 Cell Division Cycle 298.0 0 1 0 0 -0.1901334255828464 P00546 0.35026338696479803 0.12179408222436905 0.030654234811663624 0.030654234811663624 2.872733354568481 4.105466365814209 4.121933460235597 4.121933460235597 52.19218137313055 45.0 1.0 no 806 chrII_571698r 2486 essential YBR167C 170 + GCAAGGATCATCCTATGTTG Q|58|E Q|58|* 0 0 0 0 -0.36484841974058657 P38291 0.9590039849281312 0.9391661882400512 1.0855799913406372 47.53391282316608 45.0 0.0 no 807 chrII_607757r 2487 essential YBR192W 108 - TCAGATTGCTTCAAATTTAG E|43|Q E|43|K RIM2 Replication In Mitochondria 377.0 0 0 0 0 -0.14360951123213256 P38127 0.956179976463318 0.9475290179252625 0.5528981685638428 0.9000115990638733 38.01102133812185 30.0 1.0 no 808 chrII_607788 2488 essential YBR192W 136 + ATCATCCAACAGTAAAACCA H|47|D H|47|Y P|48|A P|48|S RIM2 Replication In Mitochondria 377.0 0 0 0 0 -0.5037892299315941 P38127 0.9473130106925964 0.9489949941635132 0.9562489986419678 0.9498909711837769 0.609322190284729 0.05604415014386177 0.4052210450172424 0.3665755093097687 41.276656032072076 35.0 1.0 no 809 chrII_608170 2493 essential YBR192W 518 + AACACCTATGATTCATCTGA T|174|R T|174|I P|175|A P|175|S RIM2 Replication In Mitochondria 377.0 0 0 0 0 -0.32991563286140513 P38127 0.9476869702339172 0.9472420215606691 0.9562489986419678 0.9498909711837769 0.5336956381797789 0.17585667967796326 0.7774556279182434 0.8672756552696228 42.80932366134073 35.0 1.0 no 810 chrII_608289 2499 essential YBR192W 637 + TCCGACAGTACAAGAACTCT R|214|G R|214|* silent|GTC>GTG|V|213 silent|GTC>GTT|V|213 RIM2 Replication In Mitochondria 377.0 0 0 0 0 -0.08603857950381816 P38127 0.8994590044021606 0.028203669935464862 45.31250974849128 45.0 1.0 no 811 chrII_609251r 2505 essential YBR193C 480 + ACTACGTTTAGAAACGAATA T|161|S T|161|I T|162|R T|162|M MED8 MEDiator complex 223.0 0 0 0 0 -0.10030237048137107 P38304 0.9281049966812134 0.92494398355484 0.9287580251693726 0.9313089847564696 0.37324509024620056 0.0768030658364296 0.10661260038614273 0.1236349567770958 0.186599999666214 0.2865999937057495 -0.04340000078082085 -0.7129999995231628 35.230699109329635 30.0 0.0 no 812 chrII_609374 2507 essential YBR193C 360 - TTCATCCATTCGTCCACTTC M|126|I M|126|I W|125|C W|125|* MED8 MEDiator complex 223.0 0 0 0 0 0.16097575932043456 P38304 0.9405519962310792 0.9405519962310792 0.9208570122718812 1.0 1.0 0.0 1.0099999904632568 1.0099999904632568 1.4977999925613403 52.78033109918994 45.0 0.0 no 813 chrII_609568r 2512 essential YBR193C 163 + CCAAAGCCGAACTGCCACAA silent|TCC>TCG|S|55 silent|TCC>TCT|S|55 A|57|G A|57|V MED8 MEDiator complex 223.0 0 0 0 0 0.31427052082640744 P38304 0.9392369985580444 0.9400410056114196 0.27015367150306696 0.25334233045578003 0.17499999701976776 0.8460000157356262 50.084842168215395 55.00000000000001 0.0 no 814 chrII_609681 2516 essential YBR193C 53 - AATCAAAACTAACATCTTCT D|24|H D|24|N MED8 MEDiator complex 223.0 0 0 0 0 0.4351038624566429 P38304 0.9325000047683716 0.9476670026779176 0.0 0.0 0.10980000346899033 0.08900000154972076 34.033336152352945 25.0 0.0 no 815 chrII_612681r 2518 essential YBR196C 1197 + TTCTTCCAATTGGTTCACCA F|400|L silent|TTC>TTT|F|400 F|401|L silent|TTC>TTT|F|401 PGI1 PhosphoGlucoIsomerase 554.0 0 1 0 0 -1.4205865988957076 P12709 0.9387490153312684 0.9387490153312684 0.007431191392242909 0.019943427294492718 -0.6362000107765198 -0.1289999932050705 50.54528705085892 40.0 0.0 no 816 chrII_612732r 2519 essential YBR196C 1146 + TCTACTGGTTCTATCTTGTT S|383|C S|383|F T|384|S T|384|I PGI1 PhosphoGlucoIsomerase 554.0 0 0 0 0 0.6537728672998497 P12709 0.945252001285553 0.9294660091400146 0.9491789937019348 0.9472420215606691 0.05171800777316093 0.04833333566784859 0.0109281400218606 0.0014461119426414368 47.30575944937061 35.0 0.0 no 817 chrII_612758 2520 essential YBR196C 1123 - GTCAGTAAACACGTTACCTC D|381|H D|381|N PGI1 PhosphoGlucoIsomerase 554.0 0 0 0 0 -2.625037973069504 P12709 0.9486550092697144 0.956179976463318 0.0314369760453701 0.3597965240478516 45.795687825022185 45.0 0.0 yes 818 chrII_612879r 2524 essential YBR196C 999 + GTCTGGTACAACAACTTCTT silent|GTC>GTG|V|334 silent|GTC>GTT|V|334 PGI1 PhosphoGlucoIsomerase 554.0 0 0 0 0 0.37672141634134015 P12709 44.99199150184654 40.0 0.0 no 819 chrII_612903 2525 essential YBR196C 978 - GACAACAAACCACCCAACAA L|332|F silent|TTG>TTA|L|332 L|331|F silent|TTG>TTA|L|331 PGI1 PhosphoGlucoIsomerase 554.0 0 0 0 0 -0.19491486885132286 P12709 0.9587849974632264 0.9587849974632264 0.009865252301096916 0.0077809998765587815 43.394347382197225 45.0 0.0 no 820 chrII_612937r 2527 essential YBR196C 941 + CCACTTCACCCAAACCCCAT H|315|Q silent|CAC>CAT|H|315 H|315|D H|315|Y PGI1 PhosphoGlucoIsomerase 554.0 0 0 0 0 -0.8588745330298617 P12709 0.9588389992713928 0.9473130106925964 0.9489949941635132 0.002120200777426362 0.005572885740548372 0.03350309655070305 56.997440962961655 55.00000000000001 0.0 no 821 chrII_613181 2534 essential YBR196C 700 - CTTCGACAAGAACCAGTTCT silent|TCG>TCC|S|239 silent|TCG>TCA|S|239 L|238|F silent|TTG>TTA|L|238 PGI1 PhosphoGlucoIsomerase 554.0 0 0 0 1 -0.27971662253330465 P12709 0.9587849974632264 0.0058341603726148605 1.3539999723434448 45.91553890156456 45.0 0.0 no 822 chrII_613271 2539 essential YBR196C 610 - TTCTGGGTCAACAACCTTCA E|210|Q E|210|K PGI1 PhosphoGlucoIsomerase 554.0 0 0 0 0 1.2369543584685387 P12709 0.956179976463318 0.9475290179252625 0.09452083706855774 0.09937994927167892 49.26963042373086 45.0 0.0 no 823 chrII_613458r 2545 essential YBR196C 420 + TTCTCTGAACAAGTTCGTTC F|141|L silent|TTC>TTT|F|141 S|142|C S|142|F PGI1 PhosphoGlucoIsomerase 554.0 0 1 0 0 0.004674189599578341 P12709 0.9387490153312684 0.945252001285553 0.9294660091400146 0.16009411215782166 0.15637019276618958 0.047645363956689835 43.815819702930696 40.0 0.0 no 824 chrII_613530r 2547 essential YBR196C 348 + AACAAGCCAATGTACGTTGA N|117|K silent|AAC>AAT|N|117 P|119|A P|119|S PGI1 PhosphoGlucoIsomerase 554.0 0 1 0 0 0.5466015988022093 P12709 0.9439849853515624 0.9562489986419678 0.9498909711837769 0.21682606637477875 0.22103774547576904 0.3500351309776306 43.054298622273556 40.0 0.0 no 825 chrII_613637 2549 essential YBR196C 244 - ACCGGTGACGTTAGCCTCCT G|88|R G|88|S G|88|A G|88|D PGI1 PhosphoGlucoIsomerase 554.0 0 1 0 0 -1.3257362662773442 P12709 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.4860329926013946 0.7015200853347778 0.760576069355011 0.6285775303840637 60.05540992086157 60.0 0.0 no 826 chrII_613619 2550 essential YBR196C 262 - GAACATAGCATCTCTCAAAC M|93|I M|93|I PGI1 PhosphoGlucoIsomerase 554.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.32930005193864953 P12709 0.9553959965705872 0.9553959965705872 0.020202824845910072 0.020202824845910072 40.50815852792596 40.0 0.0 no 827 chrII_613654r 2552 essential YBR196C 224 + TGCATTGATTGAACTGGCCA A|76|G A|76|V PGI1 PhosphoGlucoIsomerase 554.0 0 0 0 0 -0.6918556003747739 P12709 0.9484469890594482 0.9504740238189696 0.1151144951581955 0.09074702113866806 0.4510000050067902 1.0670000314712524 48.86828302235756 45.0 0.0 no 828 chrII_616733 2557 essential YBR198C 1771 - ATCGCATGACCATAACCTTG D|597|H D|597|N C|596|S C|596|Y TAF5 TATA binding protein-Associated Factor 798.0 0 1 0 0 -1.0698920016714033 P38129 0.9486550092697144 0.956179976463318 0.9421560168266296 0.9290120005607604 0.004363010637462139 0.013696395792067051 0.051308020949363715 0.004398111253976822 47.25141594822578 45.0 0.0 no 829 chrII_616742r 2558 essential YBR198C 1759 + ACGACCAAACCGCAAGGTTA H|587|Q silent|CAC>CAT|H|587 D|588|E silent|GAC>GAT|D|588 TAF5 TATA binding protein-Associated Factor 798.0 0 0 0 0 -0.3813217640646403 P38129 0.9588389992713928 0.9532920122146606 0.0397840291261673 0.14008152484893802 47.81001059725946 50.0 0.0 no 830 chrII_616748r 2559 essential YBR198C 1753 + CATCGCACGACCAAACCGCA S|586|W S|586|L H|587|D H|587|Y TAF5 TATA binding protein-Associated Factor 798.0 0 0 0 0 -1.4887875562648352 P38129 0.9288619756698608 0.9298099875450134 0.9473130106925964 0.9489949941635132 0.0 0.0 0.1498219519853592 0.16044270992279053 52.11721502787231 60.0 0.0 no 831 chrII_616765 2560 essential YBR198C 1739 - GCGATGCAGTGGCGAAATAA silent|TCG>TCC|S|586 silent|TCG>TCA|S|586 A|585|P A|585|T TAF5 TATA binding protein-Associated Factor 798.0 0 0 0 0 -1.185260348222576 P38129 0.9573720097541808 0.9523990154266356 0.0 0.0 46.04498590508047 50.0 0.0 no 832 chrII_616956 2567 essential YBR198C 1548 - CCCACCAAAGTTTTACACGT silent|GTG>GTC|V|522 silent|GTG>GTA|V|522 G|523|R G|523|R TAF5 TATA binding protein-Associated Factor 798.0 0 0 0 1 -0.0119441380368546 P38129 0.941340982913971 0.941340982913971 0.0 0.0 49.10526296749094 45.0 0.0 no 833 chrII_616957 2568 essential YBR198C 1547 - CCACCAAAGTTTTACACGTT V|522|L V|522|M silent|GTG>GTC|V|522 silent|GTG>GTA|V|522 TAF5 TATA binding protein-Associated Factor 798.0 0 0 0 0 0.4095582041105424 P38129 0.9539830088615416 0.9587630033493042 0.06810545176267624 0.013107744976878166 45.87239231585671 40.0 0.0 no 834 chrII_617116 2572 essential YBR198C 1388 - ACATGTCTTTATTTGTGTTT M|469|I M|469|I D|468|H D|468|N TAF5 TATA binding protein-Associated Factor 798.0 0 0 0 0 0.3938539114391697 P38129 0.9553959965705872 0.9553959965705872 0.9486550092697144 0.956179976463318 0.05552919954061508 0.05552919954061508 0.1182698905467987 0.7951752543449402 42.13893624844423 25.0 0.0 no 835 chrII_617469r 2576 essential YBR198C 1032 + CAACTAAATCAACAAACTGC L|346|V silent|CTA>TTA|L|346 TAF5 TATA binding protein-Associated Factor 798.0 0 0 0 0 0.8367137909607424 P38129 0.9512209892272948 0.4730924367904663 34.50005922746982 35.0 0.0 no 836 chrII_617536 2577 essential YBR198C 968 - TAACAAACTCCTCGTCTTTT V|329|L V|329|I TAF5 TATA binding protein-Associated Factor 798.0 0 0 0 0 0.4197439056545914 P38129 0.9539830088615416 0.9574310183525084 0.645966112613678 0.4116410911083221 43.16993228175517 35.0 0.0 no 837 chrII_617645 2579 essential YBR198C 859 - ATCAGCCAATTTTTCCCTTG D|293|H D|293|N A|292|P A|292|T TAF5 TATA binding protein-Associated Factor 798.0 0 0 0 0 0.1538894017063982 P38129 0.9486550092697144 0.956179976463318 0.9573720097541808 0.9523990154266356 0.05636259168386459 0.3604736626148224 0.23067237436771396 0.4934672713279724 50.5121007380933 40.0 0.0 no 838 chrII_617674 2580 essential YBR198C 830 - ATTCTACAATATTTGGATCT E|283|Q E|283|K V|282|L V|282|I TAF5 TATA binding protein-Associated Factor 798.0 0 0 0 0 -1.1009936669006133 P38129 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.5716257691383362 0.8996968865394592 0.5912805199623108 0.5950608253479004 -0.14834000170230865 -0.2804200053215027 -0.5867599844932556 -0.5134599804878235 38.23748638186589 25.0 0.0 no 839 chrII_617886 2581 essential YBR198C 618 - CCATGGAAGTCCTTAAAATC G|213|R G|213|S TAF5 TATA binding protein-Associated Factor 798.0 0 0 0 0 -0.02605905226958749 P38129 0.941340982913971 0.951104998588562 0.24582678079605105 0.6402860879898071 -0.03466000035405159 0.7862799763679504 42.00104202187657 40.0 0.0 no 840 chrII_617988 2583 essential YBR198C 516 - TACATGATGTAGCTTAGTTC M|178|I M|178|I TAF5 TATA binding protein-Associated Factor 798.0 0 0 0 0 -0.9994781259290146 P38129 0.9553959965705872 0.9553959965705872 0.2583727240562439 0.2583727240562439 2.9358398914337163 2.9358398914337163 42.48929325816334 35.0 0.0 no 841 chrII_618089r 2586 essential YBR198C 412 + TATCTAGCGGGCGACTAGAA S|139|C S|139|F TAF5 TATA binding protein-Associated Factor 798.0 0 0 0 0 -0.5156366433602638 P38129 0.945252001285553 0.9294660091400146 0.05524877458810806 0.06012406200170518 48.04793835490205 50.0 0.0 no 842 chrII_618116 2588 essential YBR198C 388 - ACCACCTTCTGCATCTCTCT G|136|R G|136|S G|136|A G|136|D TAF5 TATA binding protein-Associated Factor 798.0 0 0 0 0 0.0558164765119695 P38129 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.5263200402259827 0.7322649955749512 0.7516424655914307 0.626510739326477 57.98219613715531 50.0 0.0 no 843 chrII_618180r 2593 essential YBR198C 321 + TCATCAATTCCTCCGAACCC S|108|* S|108|L S|109|* S|109|L TAF5 TATA binding protein-Associated Factor 798.0 0 1 0 0 -1.2159685497086985 P38129 0.9298099875450134 0.9298099875450134 0.20383524894714355 0.21016575396060946 52.34098942516749 50.0 0.0 no 844 chrII_618216 2594 essential YBR198C 288 - TTACCTGTTTTAGTATTTGC G|102|A G|102|D G|102|R G|102|S TAF5 TATA binding protein-Associated Factor 798.0 0 1 0 0 -0.1871187353384636 P38129 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.6894954442977905 0.10686898976564407 0.07676265388727188 0.6313326358795166 43.95077704595138 30.0 0.0 no 845 chrII_618435r 2607 essential YBR198C 66 + CAACGAACTAATAATGCTGC R|24|G R|24|* TAF5 TATA binding protein-Associated Factor 798.0 0 1 0 0 -0.3887101112898936 P38129 0.8994590044021606 0.453848123550415 38.41399114202369 40.0 0.0 no 846 chrII_620890 2608 high_effect YBR200W 18 + CTCTCAAAAAGAGATAGTAA silent|CTC>CTG|L|7 silent|CTC>CTT|L|7 S|8|* S|8|L BEM1 Bud EMergence 551.0 0 0 0 1 -0.01769455791387911 P29366 33.09614545896653 30.0 1.0 no 847 chrII_620944 2609 high_effect YBR200W 72 + TCCACACCTTCTCATGATAA silent|TCC>TCG|S|25 silent|TCC>TCT|S|25 S|25|C S|25|F BEM1 Bud EMergence 551.0 0 0 0 1 0.3108506452242262 P29366 0.26175999641418457 -0.9046599864959716 47.65636410487043 40.0 1.0 no 848 chrII_620945 2610 high_effect YBR200W 73 + CCACACCTTCTCATGATAAT T|26|R T|26|I silent|TCC>TCG|S|25 silent|TCC>TCT|S|25 BEM1 Bud EMergence 551.0 1 Series([], Name: modification, dtype: object) 0 0 0 -1.3420245431367317 P29366 46.64317661206104 40.0 1.0 no 849 chrII_621132 2615 high_effect YBR200W 260 + TTCAAAGGAACTATCTTTCA S|88|* S|88|L BEM1 Bud EMergence 551.0 0 0 0 0 -1.5523970984132411 P29366 0.11532685905694963 38.290735719338564 30.0 1.0 no 850 chrII_621237r 2618 high_effect YBR200W 368 - ACACTTCAAAATAGGTTTTG V|129|L V|129|M silent|GTG>GTC|V|129 silent|GTG>GTA|V|129 BEM1 Bud EMergence 551.0 0 0 0 0 -0.277192234130936 P29366 0.15246741473674774 0.040166284888982766 36.671395702076666 30.0 1.0 no 851 chrII_621238r 2619 high_effect YBR200W 369 - AACACTTCAAAATAGGTTTT silent|GTG>GTC|V|129 silent|GTG>GTA|V|129 V|129|L V|129|M BEM1 Bud EMergence 551.0 0 0 0 0 -0.3958874724349269 P29366 0.15246741473674774 0.040166284888982766 35.37588617950871 25.0 1.0 no 852 chrII_621245r 2621 high_effect YBR200W 376 - TCTATCAAACACTTCAAAAT R|132|T R|132|K D|131|H D|131|N BEM1 Bud EMergence 551.0 0 0 0 0 -0.3924930382483488 P29366 0.019217023625969887 0.7302218079566956 0.15505343675613406 0.9491428136825562 33.661468425203225 25.0 1.0 no 853 chrII_621315 2623 high_effect YBR200W 443 + TACAAATGATTCATTAAACA T|149|R T|149|I BEM1 Bud EMergence 551.0 0 0 0 0 0.7377280603964356 P29366 0.19704590737819672 0.10482480376958847 30.923258946671357 20.0 1.0 no 854 chrII_621316 2624 high_effect YBR200W 444 + ACAAATGATTCATTAAACAT T|149|R T|149|I BEM1 Bud EMergence 551.0 0 0 0 0 -0.26909199486571217 P29366 0.19704590737819672 0.10482480376958847 31.435928695618372 20.0 1.0 no 855 chrII_621486r 2630 high_effect YBR200W 617 - TAACAAACCCAACAGGAACA V|212|L V|212|I BEM1 Bud EMergence 551.0 0 0 0 0 0.0843367244971771 P29366 0.03110164403915405 0.17848534882068634 -1.76691997051239 0.1088000014424324 40.20773368437773 40.0 1.0 no 856 chrII_621509 2631 high_effect YBR200W 637 + GCATCATAGATATTGCCACG S|213|R silent|AGC>AGT|S|213 I|214|M silent|ATC>ATT|I|214 BEM1 Bud EMergence 551.0 0 0 0 0 0.4424312345131515 P29366 0.2395727336406708 0.006062314379960298 -1.0239800214767456 0.6001999974250793 47.27971870238633 45.0 1.0 no 857 chrII_621576r 2632 high_effect YBR200W 707 - TCCATTCTTGAACAGTTGGT W|242|S W|242|* W|242|C W|242|* BEM1 Bud EMergence 551.0 0 0 0 0 -2.0148016682318213 P29366 0.0 0.0 3.3987998962402344 2.893399953842163 48.013338712521545 40.0 1.0 yes 858 chrII_621636r 2633 high_effect YBR200W 767 - GCTGCTGCTCCACAGAACCA Q|262|H silent|CAG>CAA|Q|262 Q|261|H silent|CAG>CAA|Q|261 BEM1 Bud EMergence 551.0 0 1 0 0 0.5497952657872779 P29366 0.1301390677690506 0.11659639328718185 58.57686551926406 60.0 1.0 no 859 chrII_621740r 2638 high_effect YBR200W 871 - CTTCTCATCTTCTAACCCAA E|296|D silent|GAG>GAA|E|296 E|296|Q E|296|K BEM1 Bud EMergence 551.0 0 0 0 0 -0.5709608025269853 P29366 1.0 0.29529768228530884 0.4005987048149109 0.11940000206232072 -0.4676800072193146 -0.10292000323534012 48.07451159285272 40.0 1.0 no 860 chrII_621867r 2640 high_effect YBR200W 998 - TCAACTTACCGGCCTCTGCT L|339|F silent|TTG>TTA|L|339 K|338|N silent|AAG>AAA|K|338 BEM1 Bud EMergence 551.0 0 0 0 0 0.5201514254032109 P29366 0.17256782948970795 0.29762738943099976 -0.19988000392913816 1.0662599802017212 0.6922221779823303 1.2698001861572266 56.96984798761475 55.00000000000001 1.0 no 861 chrII_621868r 2641 high_effect YBR200W 999 - CTCAACTTACCGGCCTCTGC L|339|F silent|TTG>TTA|L|339 K|338|N silent|AAG>AAA|K|338 BEM1 Bud EMergence 551.0 0 0 0 0 1.0167618761038828 P29366 0.17256782948970795 0.29762738943099976 -0.19988000392913816 1.0662599802017212 0.6922221779823303 1.2698001861572266 56.96984798761475 60.0 1.0 no 862 chrII_626035 2652 essential YBR202W 263 + TCAAAACGAAAAGTTTCTCC Q|89|E Q|89|* N|90|K silent|AAC>AAT|N|90 MCM7 MiniChromosome Maintenance 845.0 0 0 0 0 0.2573301387367089 P38132 0.922443985939026 0.9035819768905641 1.0 0.23828081786632535 36.95077556927339 35.0 1.0 no 863 chrII_626203r 2656 essential YBR202W 434 - TCTCATTCCTCAGTCTCCTT E|151|Q E|151|K E|151|D silent|GAG>GAA|E|151 MCM7 MiniChromosome Maintenance 845.0 0 0 0 0 -3.0453977898954583 P38132 0.9202449917793274 0.9081959724426271 0.912388026714325 0.6511221528053284 0.5996195077896118 0.5818276405334473 57.11179891964491 45.0 1.0 yes 864 chrII_626298r 2664 essential YBR202W 529 - TTCTCTTAACGCATCATTCA E|183|Q E|183|K R|182|T R|182|K MCM7 MiniChromosome Maintenance 845.0 0 0 0 0 -0.6365781611093547 P38132 0.9315000176429749 0.9194509983062744 0.900963008403778 0.9193329811096193 0.4231487214565277 0.7113109230995178 0.1823716014623642 1.0 44.76842807125343 35.0 1.0 no 865 chrII_626433 2666 essential YBR202W 661 + GTTCTAAACCATTATCTGTT S|222|C S|222|F MCM7 MiniChromosome Maintenance 845.0 0 0 0 0 0.017134414704481567 P38132 0.9077129960060121 0.8902170062065125 0.16441388428211212 0.5684424042701721 42.057933430485654 30.0 1.0 no 866 chrII_626515 2669 essential YBR202W 743 + TTCTGATGTCAAACCAGCTG S|249|C S|249|F MCM7 MiniChromosome Maintenance 845.0 0 0 0 0 -1.3752984429974018 P38132 0.9077129960060121 0.8902170062065125 0.012579881586134434 0.007125353906303644 46.37257674283956 45.0 1.0 no 867 chrII_626553r 2671 essential YBR202W 784 - TTCGTACCCACATTGATCGC E|268|Q E|268|K silent|GGG>GGC|G|266 silent|GGG>GGA|G|266 MCM7 MiniChromosome Maintenance 845.0 0 0 0 0 -0.0689135553048794 P38132 0.9315000176429749 0.9194509983062744 0.09473607689142227 0.01986931636929512 51.77300400648864 50.0 1.0 no 868 chrII_626759 2673 essential YBR202W 987 + TCGCTAAATATCCACGTTAA L|331|V silent|CTA>TTA|L|331 S|330|W S|330|L MCM7 MiniChromosome Maintenance 845.0 0 0 0 0 0.17506350910194987 P38132 0.9779649972915648 0.9502170085906982 0.9589700102806092 0.3175411522388458 0.002684257924556732 0.01290670782327652 41.61309667742563 35.0 1.0 no 869 chrII_626770r 2676 essential YBR202W 1001 - TTACCAGCGTCCCGTTAACG V|340|L V|340|I silent|CTG>CTC|L|339 silent|CTG>CTA|L|339 MCM7 MiniChromosome Maintenance 845.0 0 1 0 0 0.10376163138102426 P38132 0.9131360054016112 0.9208049774169922 0.050413742661476135 0.06585069745779037 53.23500601983375 55.00000000000001 1.0 no 870 chrII_626834 2677 essential YBR202W 1062 + TTCTTGCCAGCGCCCTACAC F|355|L silent|TTC>TTT|F|355 P|357|A P|357|S MCM7 MiniChromosome Maintenance 845.0 0 0 0 0 0.4850809764501406 P38132 0.9022229909896852 1.0004199743270874 0.9926369786262512 0.013951902277767658 0.0 0.0 60.49580442034983 60.0 1.0 no 871 chrII_626881 2679 essential YBR202W 1109 + ACTGACAGAAACTTATTTAG L|371|V silent|CTG>TTG|L|371 T|372|R T|372|I MCM7 MiniChromosome Maintenance 845.0 0 0 0 0 0.21956943990071068 P38132 0.9282950162887572 0.8982250094413757 0.9084240198135376 0.1922057420015335 0.00974367279559374 0.010702784173190594 34.92320619447588 30.0 1.0 no 872 chrII_627062 2685 essential YBR202W 1290 + GCGTTGCTGCTATTACTTGT A|431|G A|431|V L|433|V silent|CTG>TTG|L|433 MCM7 MiniChromosome Maintenance 845.0 0 0 0 0 0.8469009844881159 P38132 0.9109870195388794 0.9102140069007874 0.9950990080833436 0.03969994187355042 0.0756106823682785 0.0 52.29551656202182 45.0 1.0 no 873 chrII_627219r 2690 essential YBR202W 1450 - GCCTGAGGAACCCTTACCAG G|490|R G|490|S G|490|A G|490|D MCM7 MiniChromosome Maintenance 845.0 0 1 0 0 -2.7230199879684256 P38132 0.9727219939231871 0.9916149973869324 0.9903749823570251 0.9780880212783812 0.0 0.0 0.0 0.0 56.478839164749964 60.0 1.0 yes 874 chrII_627400 2696 essential YBR202W 1628 + ACAAACAATTTCGATATCCA Q|544|E Q|544|* T|545|R T|545|I MCM7 MiniChromosome Maintenance 845.0 0 0 0 0 -0.21536994308102225 P38132 1.0026899576187134 0.9094799757003784 0.9196789860725404 0.0 0.0 0.0 38.39812111203491 30.0 1.0 no 875 chrII_627404 2698 essential YBR202W 1632 + ACAATTTCGATATCCAAGGC T|545|R T|545|I MCM7 MiniChromosome Maintenance 845.0 0 0 0 0 0.1423627547503459 P38132 0.9094799757003784 0.9196789860725404 0.0 0.0 43.631255563967336 40.0 1.0 no 876 chrII_646460 2704 essential YBR211C 653 - TTCGTACCGATATTATCTGC R|224|P R|224|Q V|223|L V|223|I AME1 Associated with Microtubules and Essential 324.0 0 0 0 0 0.43539183387677016 P38313 0.9099509716033936 0.949662983417511 0.9539830088615416 0.9574310183525084 0.01967362500727177 0.2161046266555786 0.18454459309577945 0.5252835750579834 45.9594526286486 40.0 0.0 no 877 chrII_646807 2708 essential YBR211C 306 - TCATCATTTCTAACATTTTG E|109|Q E|109|K D|108|H D|108|N AME1 Associated with Microtubules and Essential 324.0 0 0 0 0 -0.17512700866422626 P38313 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.43965229392051697 0.6173505187034607 0.01875939592719078 0.05011746287345886 37.454673302976005 25.0 0.0 no 878 chrII_646892 2709 essential YBR211C 221 - GCTGATACCCATGTTCATGA Q|80|H silent|CAG>CAA|Q|80 AME1 Associated with Microtubules and Essential 324.0 0 0 0 0 -1.3068146070456406 P38313 0.9570760130882264 0.027651315554976463 51.03900526047658 45.0 0.0 no 879 chrII_646916r 2711 essential YBR211C 194 + CACTAATAACGTAAATGCGC T|66|S T|66|I AME1 Associated with Microtubules and Essential 324.0 0 0 0 0 0.8271956947446194 P38313 0.9491789937019348 0.9472420215606691 0.5960248112678528 0.14405986666679382 38.67547342444289 40.0 0.0 no 880 chrII_646917 2712 essential YBR211C 196 - CTGCGCATTTACGTTATTAG silent|GCG>GCC|A|71 silent|GCG>GCA|A|71 A|71|P A|71|T AME1 Associated with Microtubules and Essential 324.0 0 0 0 0 -0.3623268353049791 P38313 0.9573720097541808 0.9523990154266356 44.5277900566324 40.0 0.0 no 881 chrII_646951 2713 essential YBR211C 162 - TCGAAAGAATTCGCAAGTTT E|61|Q E|61|K AME1 Associated with Microtubules and Essential 324.0 0 1 0 0 -3.837434199948991 P38313 0.956179976463318 0.9475290179252625 0.4670051634311676 0.6642101407051086 38.94590224381909 35.0 0.0 yes 882 chrII_647017 2714 essential YBR211C 96 - TCCTCTCTATAAACAGCATT E|38|D silent|GAG>GAA|E|38 E|39|Q E|39|K AME1 Associated with Microtubules and Essential 324.0 0 1 0 0 -0.19505761848740266 P38313 0.94931298494339 0.956179976463318 0.9475290179252625 0.6221488118171692 0.6952270865440369 0.8264002203941345 44.36676834879871 35.0 0.0 no 883 chrII_685720 2716 essential YBR234C 853 - CGCAAATTTCCAGCCTTCAG A|291|P A|291|T ARC40 ARp2/3 Complex subunit 384.0 0 0 0 0 -0.17958421489463233 P38328 0.24588076770305636 0.8852062821388245 -0.4814000129699707 0.2899999916553497 50.614696772426846 50.0 0.0 no 884 chrII_685920 2720 essential YBR234C 653 - GACTTCTCCATTCCACATCA S|224|T S|224|N R|223|T R|223|K ARC40 ARp2/3 Complex subunit 384.0 0 0 0 0 1.6459147600820807 P38328 0.03434252738952637 0.14756038784980774 0.02845614776015282 0.013173903338611126 52.53593884549372 45.0 0.0 no 885 chrII_685965r 2721 essential YBR234C 605 + CCCTTTTGGTTGTTTAATCA P|203|R P|203|L P|203|A P|203|S ARC40 ARp2/3 Complex subunit 384.0 0 0 0 0 0.08553495760189687 P38328 0.01334652118384838 0.004012519959360361 0.05156753957271576 0.011587778106331824 47.971563055959166 35.0 0.0 no 886 chrII_685974 2722 essential YBR234C 599 - AACAACCAAAAGGGAATTTC C|206|S C|206|Y G|205|A G|205|D ARC40 ARp2/3 Complex subunit 384.0 0 0 0 0 -2.415760901121257 P38328 0.6857208013534546 0.07381636649370192 0.020121948793530464 0.08364874869585037 0.4501999914646149 -0.8637999892234802 36.219830332824756 35.0 0.0 yes 887 chrII_686222 2730 essential YBR234C 351 - ACAGCAAACTTATAACCATT V|124|L V|124|I A|123|P A|123|T ARC40 ARp2/3 Complex subunit 384.0 0 1 0 0 -0.6754559799026307 P38328 0.06219681724905968 0.01759891398251057 0.0 0.0 39.16566604636199 30.0 0.0 no 888 chrII_686247r 2732 essential YBR234C 323 + AGCAGCTACTTCAGTTACAT A|109|G A|109|V A|110|G A|110|V ARC40 ARp2/3 Complex subunit 384.0 0 0 0 0 0.5545380125039118 P38328 0.01818235963582993 0.0061672148294746884 0.0 0.0 0.34439998865127563 0.9696000218391418 1.753000020980835 1.3655999898910522 48.39706029386667 40.0 0.0 no 889 chrII_686325r 2735 essential YBR234C 245 + AGACCGTAATGCTTACGTTT D|83|E silent|GAC>GAT|D|83 R|84|G R|84|C ARC40 ARp2/3 Complex subunit 384.0 0 0 0 0 0.2560327386412027 P38328 0.01188800111413002 0.004130295477807522 0.0005152411758899689 1.883800029754639 -3.704999923706055 -0.2980000078678131 46.26578356226997 40.0 0.0 no 890 chrII_686467 2741 essential YBR234C 106 - ACAATCTGTTTCGCATGTAA C|42|S C|42|Y D|41|H D|41|N ARC40 ARp2/3 Complex subunit 384.0 0 0 0 0 -0.10452985408298268 P38328 0.6550179719924927 0.041138283908367164 0.4725218415260315 1.0 42.951301690272096 35.0 0.0 no 891 chrII_686560 2743 essential YBR234C 13 - AACGGACTTGTCTTTAGAAT V|11|L V|11|I K|9|N silent|AAG>AAA|K|9 ARC40 ARp2/3 Complex subunit 384.0 0 0 0 0 0.6523010910423888 P38328 0.3617236912250519 0.32746827602386475 0.01612180471420288 40.669896229723356 35.0 0.0 no 892 chrII_690963 2745 essential YBR236C 711 - TCACACGGAAATCTACAGTC C|243|S C|243|Y D|244|H D|244|N ABD1 436.0 0 0 0 0 -0.4221843778929386 P32783 0.9421560168266296 0.9290120005607604 0.9486550092697144 0.956179976463318 0.08791057020425798 0.2008577138185501 0.0 0.0 43.132491984020525 45.0 0.0 no 893 chrII_690822 2747 essential YBR236C 852 - TAACGAATGAATTCTGAATC R|290|P R|290|H ABD1 436.0 0 0 0 0 -3.3678419241047317 P32783 0.9099509716033936 0.9570810198783876 0.23633578419685364 0.15702541172504425 33.147374757806396 30.0 0.0 yes 894 chrII_691054r 2751 essential YBR236C 617 + ATACCGGTCCATGAGAAATT Y|207|* silent|TAC>TAT|Y|207 R|208|G R|208|W ABD1 436.0 0 0 0 0 -1.0548468693526694 P32783 0.8994590044021606 0.9448130130767822 0.17947764694690704 0.008847994729876518 44.905634498448194 40.0 0.0 no 895 chrII_691306 2756 essential YBR236C 368 - TACGTTCATTATAGTGCTCT R|129|P R|129|H E|128|Q E|128|K ABD1 436.0 0 0 0 0 -0.14423983610905622 P32783 0.9099509716033936 0.9570810198783876 0.956179976463318 0.9475290179252625 0.010783448815345764 0.011554082855582236 0.4951054453849793 0.33660730719566345 45.48251479743181 35.0 0.0 no 896 chrII_691328 2757 essential YBR236C 346 - GACAATCTGGTCAACATTTA V|122|L V|122|I Q|120|H silent|CAG>CAA|Q|120 ABD1 436.0 0 0 0 0 0.503998253199741 P32783 0.9539830088615416 0.9574310183525084 0.9570760130882264 0.04036128148436546 0.4281575679779053 0.05346934497356415 40.909637604974186 35.0 0.0 no 897 chrII_691432r 2758 essential YBR236C 239 + ACATGAAAGGTATGATCAAG H|81|D H|81|Y ABD1 436.0 0 0 0 0 -1.7933656805511025 P32783 0.9473130106925964 0.9489949941635132 0.6330698132514954 0.373544991016388 35.96220520991602 35.0 0.0 no 898 chrII_691620r 2763 essential YBR236C 51 + CGTCAGTACGGCTCAATTAC Q|19|E Q|19|* ABD1 436.0 0 0 0 0 -2.6728788793071705 P32783 0.9590039849281312 47.718187862651405 50.0 0.0 yes 899 chrII_691650 2764 essential YBR236C 24 - TCTTCTTGTGACATCCATAT D|15|H D|15|N E|14|Q E|14|K ABD1 436.0 0 1 0 0 0.10225576740293148 P32783 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 46.50046064013885 35.0 0.0 no 900 chrII_692162 2771 essential YBR237W 193 + AACGTGTAAAAGAAGAGCTT R|66|G R|66|C 0 0 0 0 0.4358584728110727 P21372 0.2335866689682007 0.03360828012228012 36.79313501489156 35.0 1.0 no 901 chrII_692353r 2775 essential YBR237W 387 - TCTTTTTCATTATCATGCTC D|136|H D|136|N 0 0 0 0 0.06207222977665641 P21372 0.0 0.0 43.74219818979492 30.0 1.0 no 902 chrII_692645r 2778 essential YBR237W 679 - AACTTCCATCTCTGACATCG V|233|L V|233|I E|232|Q E|232|K 0 0 0 0 1.1144889123381547 P21372 0.148606076836586 0.3588675856590271 0.03049266897141933 0.02426370978355408 -0.17319999635219574 -0.4727599918842316 0.16784000396728516 0.2096399962902069 47.093467277063844 45.0 1.0 no 903 chrII_692720r 2780 essential YBR237W 754 - AGACCACTTTGTGACTGGTT W|257|C W|257|* W|257|S W|257|* 0 0 0 0 -1.4235156696681668 P21372 0.0037992177531123157 0.005506576038897038 4.733540058135986 5.997260093688965 50.25638425273593 45.0 1.0 no 904 chrII_692739 2781 essential YBR237W 770 + GTCTCAACTGGGACTATCAA S|258|C S|258|F Q|259|E Q|259|* 0 0 0 0 -0.5476729773277271 P21372 0.030493322759866718 0.04203922301530838 0.05587232857942581 -0.3170999884605408 -0.042500000447034836 -0.09532000124454497 46.102422381569795 45.0 1.0 no 905 chrII_692824 2783 essential YBR237W 855 + GCTCTTCCCGCTATTATGTC L|287|V L|287|F A|286|G A|286|V 0 0 0 0 -0.019026543488687386 P21372 0.12214194983243942 0.03312909975647926 0.05960603803396225 0.06241352111101151 3.3868799209594727 8.621540069580076 1.409600019454956 3.7163999080657963 56.12753483295126 50.0 1.0 no 906 chrII_692905r 2785 essential YBR237W 939 - GCTTTTACTTGTCTTAGCAA A|320|P A|320|T 0 0 0 0 1.062138229746655 P21372 0.21070808172225952 0.3370485305786133 3.6419799327850337 0.8970400094985962 46.071247638256644 35.0 1.0 no 907 chrII_693247r 2790 essential YBR237W 1281 - TTCATGATTTGCGTTATTTG M|433|I M|433|I 0 1 0 0 0.7208871461329318 P21372 0.242694228887558 0.242694228887558 2.252700090408325 2.252700090408325 41.11027523669271 30.0 1.0 no 908 chrII_693592 2794 essential YBR237W 1623 + TCAAAAAAGCTGTTAAATGC S|542|* S|542|L 0 0 0 0 0.8397659237723737 P21372 0.7261832952499391 -1.4579399824142456 33.565738170503614 30.0 1.0 no 909 chrII_693646r 2795 essential YBR237W 1680 - TTCATAAGCCTTTCTTGATA M|566|I M|566|I 0 0 0 0 0.12916771279872347 P21372 0.433814138174057 0.433814138174057 0.37648001313209534 0.37648001313209534 43.29006277907375 30.0 1.0 no 910 chrII_705963 2804 essential YBR243C 811 - ATTCCATTTCCATAGCGCCA W|276|C W|276|* W|276|S W|276|* 0 0 0 0 0.9775433809006684 P07286 0.8858469724655151 0.8858469724655151 0.009175501763820648 0.022946668788790703 55.02807459122897 45.0 0.0 no 911 chrII_706023r 2811 essential YBR243C 748 + TAGCCACAAGAGACTCCCAT A|251|G A|251|V silent|GCC>GCG|A|251 silent|GCC>GCT|A|251 0 0 0 0 0.1998477562235948 P07286 0.9484469890594482 0.9504740238189696 0.31461256742477417 0.3870134055614472 52.28305796086636 50.0 0.0 no 912 chrII_706132r 2816 essential YBR243C 639 + AACTCCATCAACATCCTGGC N|214|K silent|AAC>AAT|N|214 S|215|C S|215|F 0 0 0 0 -2.8925082461510985 P07286 0.9439849853515624 0.945252001285553 0.9294660091400146 0.013637172989547251 0.0025134996976703405 0.0011381196090951562 51.08438880745279 50.0 0.0 yes 913 chrII_706610 2833 essential YBR243C 164 - TACTCAAGTCCTTACCGAAT S|61|T S|61|N L|60|F silent|TTG>TTA|L|60 0 0 0 0 0.2744997288844026 P07286 0.9512869715690612 0.9536849856376648 0.9587849974632264 0.8563715219497681 0.31660738587379456 0.022193411365151402 45.790289688102796 40.0 0.0 no 914 chrII_713370 2844 essential YBR247C 1066 - TAGCCTTAAAAGATAACTCA R|361|S silent|AGG>AGA|R|361 R|361|T R|361|K ENP1 Essential Nuclear Protein 483.0 0 0 0 0 -1.1325638107849825 P38333 0.9087679982185364 0.932735025882721 0.955805003643036 0.041170932352542884 0.033193942159414284 0.06688429415225983 37.439464227963704 30.0 0.0 no 915 chrII_713373r 2845 essential YBR247C 1060 + CTGCCTTGAGTTATCTTTTA A|355|G A|355|V silent|GCC>GCG|A|355 silent|GCC>GCT|A|355 ENP1 Essential Nuclear Protein 483.0 0 0 0 0 0.5264660298928987 P38333 0.9484469890594482 0.9504740238189696 0.0 0.0 47.28773069378309 35.0 0.0 no 916 chrII_713411r 2848 essential YBR247C 1022 + GCTTGCTAAAGTCTCTGTTC L|342|V L|342|F A|343|G A|343|V ENP1 Essential Nuclear Protein 483.0 0 1 0 0 -0.7696367286638215 P38333 0.9512209892272948 0.9587849974632264 0.9484469890594482 0.9504740238189696 0.02124208211898804 0.016183769330382347 0.1524295061826706 0.5398281216621399 49.16436895576346 45.0 0.0 no 917 chrII_713464 2849 essential YBR247C 972 - TTACACCCTGTTTCAACCAA C|330|S C|330|Y silent|GGG>GGC|G|329 silent|GGG>GGA|G|329 ENP1 Essential Nuclear Protein 483.0 0 0 0 0 0.5568038875198617 P38333 0.9421560168266296 0.9290120005607604 0.011851870454847813 0.00898529402911663 48.28894817672028 40.0 0.0 no 918 chrII_713465 2850 essential YBR247C 971 - TACACCCTGTTTCAACCAAT C|330|S C|330|Y silent|GGG>GGC|G|329 silent|GGG>GGA|G|329 ENP1 Essential Nuclear Protein 483.0 0 0 0 0 0.037646462358573336 P38333 0.9421560168266296 0.9290120005607604 0.011851870454847813 0.00898529402911663 48.027173396961594 40.0 0.0 no 919 chrII_713497r 2852 essential YBR247C 936 + AAACCAAGTGCCTTCTTCAA P|314|A P|314|S P|314|R P|314|L ENP1 Essential Nuclear Protein 483.0 0 1 0 0 -0.12571455721801986 P38333 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.035495415329933167 0.02363003045320511 0.11186322569847107 0.013243396766483784 46.153266859668925 40.0 0.0 no 920 chrII_713721 2855 essential YBR247C 715 - GACATCTTGCCAATTTCTTA V|245|L V|245|I D|244|H D|244|N ENP1 Essential Nuclear Protein 483.0 0 0 0 0 0.058927858057169484 P38333 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 0.7391300797462463 1.0 0.014068442396819592 0.035312090069055564 45.56744217672826 35.0 0.0 no 921 chrII_713940 2861 essential YBR247C 496 - ACTTTCCTTTTCTCGGATAG S|172|T S|172|N E|171|Q E|171|K ENP1 Essential Nuclear Protein 483.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.6528658038246863 P38333 0.9512869715690612 0.9536849856376648 0.956179976463318 0.9475290179252625 0.2673968076705933 0.13485155999660492 0.10428085923194884 0.02676052413880825 47.65505651824151 40.0 0.0 no 922 chrII_714156 2864 essential YBR247C 280 - GTCTTCATCATCATAGCTCA D|100|H D|100|N E|99|Q E|99|K ENP1 Essential Nuclear Protein 483.0 0 0 0 0 -0.6497926787811135 P38333 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.6003847718238831 0.5945777297019958 0.4177727699279785 0.6576735973358154 49.4840537177804 40.0 0.0 no 923 chrII_714260r 2869 essential YBR247C 173 + ATCAAGAAAAATTTTGCAGT S|59|* S|59|L ENP1 Essential Nuclear Protein 483.0 0 0 0 0 1.0388633774273202 P38333 0.9298099875450134 0.005099629983305931 34.22893064448812 25.0 0.0 no 924 chrII_722734r 2880 essential YBR252W 126 - ACCATACCTTGACCCATAGC M|48|I M|48|I V|49|L V|49|I DUT1 DUTp pyrophosphatase 147.0 0 0 0 0 -1.5027869958767068 P33317 0.13844583928585052 0.13844583928585052 0.06709086149930954 0.1637469381093979 -0.22689999639987946 -0.22689999639987946 2.215399980545044 0.35545998811721796 -0.3687199950218201 -0.3687199950218201 -0.2295999974012375 -0.2295999974012375 53.95693347476202 50.0 1.0 no 925 chrII_722846r 2891 essential YBR252W 238 - TCTGTCGACAACACCAGCAC R|86|T R|86|K D|85|H D|85|N DUT1 DUTp pyrophosphatase 147.0 0 1 0 0 -1.2127646109229506 P33317 0.42867663502693176 0.7079129219055176 0.0 0.0 0.013159999623894691 -0.2269800007343292 0.5948600172996521 0.2616400122642517 -0.07231999933719635 -0.09505999833345412 -0.2065799981355667 0.3143799901008606 50.84712015408985 55.00000000000001 1.0 no 926 chrII_722940 2892 essential YBR252W 329 + TCGCGTAGCCCAATTGATTC silent|CGC>CGG|R|111 silent|CGC>CGT|R|111 R|111|G R|111|C DUT1 DUTp pyrophosphatase 147.0 0 0 0 0 0.4172167687043107 P33317 0.001166289672255516 0.00013066180690657347 1.4943200349807741 0.1988999992609024 51.736249873909685 50.0 1.0 no 927 chrII_723322r 2893 essential YBR253W 55 - TATCAATTCCGCCAGCTTCA L|24|F silent|TTG>TTA|L|24 0 0 0 0 0.8510677836882629 P32570 0.9587849974632264 0.0 0.911981999874115 -0.21211999654769895 1.2670667171478271 52.38873220643973 45.0 1.0 no 928 chrII_723454r 2894 essential YBR253W 187 - AACATTTTTAATCAATTGCA V|69|L V|69|I 0 0 0 0 -0.19399462875656195 P32570 0.9539830088615416 0.9574310183525084 0.06814146786928177 0.4948284327983856 -1.3433040380477903 -0.8990899920463562 -0.9278799891471864 -1.1266000270843506 -0.5244899988174438 -0.2291000187397003 34.968495034086125 20.0 1.0 no 929 chrII_723496r 2897 essential YBR253W 229 - CCATTTCTCTTTTATCGATC W|83|S W|83|* E|81|D silent|GAG>GAA|E|81 0 0 0 0 0.11014197708173018 P32570 0.8858469724655151 0.94931298494339 0.0 0.0 0.5335339903831482 0.7970119714736938 0.31275999546051025 5.527939796447754 45.14779479879643 35.0 1.0 no 930 chrII_723521 2898 essential YBR253W 251 + ACTGAACCAAATTCCTGTAA L|85|V silent|CTG>TTG|L|85 N|86|K silent|AAC>AAT|N|86 0 0 0 0 0.7301034331336322 P32570 0.9512209892272948 0.9439849853515624 0.0 0.3010300099849701 1.2885299921035769 -0.3619619905948639 0.8333799839019775 0.3744199872016907 -0.1936399936676025 41.39380424835071 35.0 1.0 no 931 chrII_723886 2899 essential YBR254C 358 - GTCAATAACTACGCTACTGT D|126|H D|126|N TRS20 TRapp Subunit 175.0 0 0 0 0 -0.3200463470220817 P38334 0.040595095604658134 0.30010494589805603 43.55874488216711 40.0 0.0 no 932 chrII_727631r 2911 essential YBR256C 449 + AACTTCCTTGACCATAATCA T|151|S T|151|I S|152|C S|152|F RIB5 RIBoflavin biosynthesis 238.0 0 0 0 0 0.026936572857251373 P38145 0.9491789937019348 0.9472420215606691 0.945252001285553 0.9294660091400146 0.018252082169055942 0.16109202802181244 0.0 0.0 44.180069466590005 35.0 0.0 no 933 chrII_727783r 2912 essential YBR256C 297 + TTCGGTGGTCATTATGTACA F|100|L silent|TTC>TTT|F|100 RIB5 RIBoflavin biosynthesis 238.0 0 0 0 0 -0.5293479031403555 P38145 0.9387490153312684 0.15435445308685306 0.5374000072479248 47.380809561173685 40.0 0.0 no 934 chrII_727857r 2919 essential YBR256C 223 + AACGAAGTAATGTCGCTTCC R|76|G R|76|* RIB5 RIBoflavin biosynthesis 238.0 0 1 0 0 -0.21309310607953108 P38145 0.8994590044021606 0.054773956537246704 1.6169999837875366 44.84656093876873 45.0 0.0 no 935 chrII_727870 2920 essential YBR256C 213 - TTACTTCGTTTTATAGTTTC S|77|T S|77|N R|76|P R|76|Q RIB5 RIBoflavin biosynthesis 238.0 0 1 0 0 -0.06565839404219702 P38145 0.9512869715690612 0.9536849856376648 0.9099509716033936 0.949662983417511 1.0 0.005584918428212404 0.06392548233270645 0.16118872165679932 -2.433919906616211 2.992719888687134 2.8311800956726074 0.7920600175857544 39.59886605221243 25.0 0.0 no 936 chrII_727969r 2921 essential YBR256C 111 + ATTCTCACCGATTGTCACGT L|39|V L|39|F silent|CTC>CTG|L|39 silent|CTC>CTT|L|39 RIB5 RIBoflavin biosynthesis 238.0 0 0 0 0 1.1901892889404802 P38145 0.9512209892272948 0.9587849974632264 0.017027806490659714 0.013561248779296877 3.695600032806397 8.408200263977049 50.49611605431574 45.0 0.0 no 937 chrII_728032 2925 essential YBR256C 51 - CCACTTTCAGAGTCATCATA S|23|T S|23|N G|24|R G|24|R RIB5 RIBoflavin biosynthesis 238.0 0 0 0 0 0.3212195914890713 P38145 0.9512869715690612 0.9536849856376648 0.941340982913971 0.941340982913971 1.0 0.09460540860891342 0.01029833871871233 0.01029833871871233 -0.8537999987602234 -0.8537999987602234 47.51148213190754 40.0 0.0 no 938 chrII_728917 2929 essential YBR257W 32 + TCTTTTCACGAAATGCCTGG L|12|V L|12|F F|13|L silent|TTC>TTT|F|13 POP4 Processing Of Precursor RNAs 279.0 0 0 0 0 0.18814454959623492 P38336 0.0639200434088707 0.0346568338572979 1.0 46.52240358436217 45.0 1.0 no 939 chrII_729232 2931 essential YBR257W 347 + AGACCTTTTACACTACATAG D|117|E silent|GAC>GAT|D|117 L|118|V L|118|F POP4 Processing Of Precursor RNAs 279.0 0 0 0 0 -0.25338360550154393 P38336 1.0 0.21775828301906586 0.17215076088905334 41.55180629626079 35.0 1.0 no 940 chrII_729235r 2932 essential YBR257W 353 - TCTCCTCTATGTAGTGTAAA E|124|Q E|124|K E|124|D silent|GAG>GAA|E|124 POP4 Processing Of Precursor RNAs 279.0 0 0 0 0 0.2396380620030108 P38336 0.19626598060131076 0.4315623641014099 0.2285078763961792 44.383441009159576 35.0 1.0 no 941 chrII_729181 2933 essential YBR257W 296 + TACAAAAAAATGTCTGAAAT T|100|R T|100|I POP4 Processing Of Precursor RNAs 279.0 0 0 0 0 0.044978215485226784 P38336 0.5388606786727905 0.2439786791801453 27.717797879716894 20.0 1.0 no 942 chrII_729388 2934 essential YBR257W 503 + AGCATTATTAAAACTATCTA A|169|G A|169|V POP4 Processing Of Precursor RNAs 279.0 0 0 0 0 0.8507765119854592 P38336 0.07639560103416443 1.0 33.42772797217049 20.0 1.0 no 943 chrII_729469r 2937 essential YBR257W 587 - CCCAGATCACAATGCCTTGA W|202|S W|202|* W|202|C W|202|* POP4 Processing Of Precursor RNAs 279.0 0 0 0 0 0.0007081033859102082 P38336 0.05669045075774193 0.03060182370245457 52.29972534609419 50.0 1.0 no 944 chrII_738755r 2939 essential YBR265W 176 - CGTCAGTGGTTTCCCTTCTC D|65|H D|65|N TSC10 Temperature-sensitive Suppressors of Csg2 mutants 320.0 0 0 0 0 -0.5272176218061358 P38342 58.84080308460102 55.00000000000001 1.0 no 945 chrII_738769r 2940 essential YBR265W 190 - TTGCACTTGGCCCTCGTCAG silent|GTG>GTC|V|69 silent|GTG>GTA|V|69 V|69|L V|69|M TSC10 Temperature-sensitive Suppressors of Csg2 mutants 320.0 0 0 0 0 -0.0722798633402541 P38342 59.59170546331779 60.0 1.0 no 946 chrII_738908r 2949 essential YBR265W 329 - CACAGCATAACGTTTGTGTA C|116|S C|116|Y C|115|S C|115|Y TSC10 Temperature-sensitive Suppressors of Csg2 mutants 320.0 0 0 0 0 -0.0832775420519862 P38342 0.05583078414201737 0.005700279027223587 0.4609235525131226 1.0 44.45288149609337 40.0 1.0 no 947 chrII_738913 2951 essential YBR265W 331 + CACAAACGTTATGCTGTGCA Q|112|E Q|112|* T|113|R T|113|M TSC10 Temperature-sensitive Suppressors of Csg2 mutants 320.0 0 0 0 0 -0.936947575811188 P38342 0.4115535616874695 0.017349150031805042 0.05351142585277557 46.015913203792316 45.0 1.0 no 948 chrII_739037r 2959 essential YBR265W 458 - GTTCCTTGGTTTGCTCTGCA E|159|Q E|159|K K|158|N silent|AAG>AAA|K|158 TSC10 Temperature-sensitive Suppressors of Csg2 mutants 320.0 0 0 0 0 0.1627396676244255 P38342 0.5782309770584106 0.9185873866081238 0.4784953892230988 58.75154530796118 50.0 1.0 no 949 chrII_739086 2961 essential YBR265W 504 + ACCGCGCTTTACCCATTTGT silent|ACC>ACG|T|169 silent|ACC>ACT|T|169 T|169|S T|169|I TSC10 Temperature-sensitive Suppressors of Csg2 mutants 320.0 0 0 0 0 0.08063857833243204 P38342 0.05976647138595581 0.3239608108997345 56.50563288574483 50.0 1.0 no 950 chrII_739203 2966 essential YBR265W 621 + CCTGGTAATTTTGAAAGCGA P|208|R P|208|L TSC10 Temperature-sensitive Suppressors of Csg2 mutants 320.0 0 0 0 0 0.6823130755968261 P38342 0.0 0.0 42.96825269396345 40.0 1.0 no 951 chrII_739251r 2967 essential YBR265W 672 - TCGATCAACTTTGTAATTTC E|231|Q E|231|K L|229|F silent|TTG>TTA|L|229 TSC10 Temperature-sensitive Suppressors of Csg2 mutants 320.0 0 0 0 0 0.005432310369280803 P38342 0.0 0.0 0.05204615741968155 38.230238844307905 30.0 1.0 no 952 chrII_739292r 2970 essential YBR265W 713 - TATCACATGCTTGTTTGCAT D|244|H D|244|N C|243|S C|243|Y TSC10 Temperature-sensitive Suppressors of Csg2 mutants 320.0 0 1 0 0 -0.6115205759865507 P38342 0.04106031730771065 0.325944185256958 0.4463856816291809 0.07589099556207657 46.512399650531165 35.0 1.0 no 953 chrII_741399 2974 high_effect YBR268W 100 + CATCGCTTAACTTAAACATA S|35|W S|35|L L|36|V L|36|F MRPL37 Mitochondrial Ribosomal Protein, Large subunit 105.0 0 0 0 0 0.189134372161243 P36532 0.03332320600748062 0.3616802096366882 0.03528272733092308 0.02332619018852711 37.223227218535726 30.0 1.0 no 954 chrII_761316 2979 high_effect YBR279W 59 + ACAATTACCTCCTAAACTTC Q|21|E Q|21|* PAF1 RNA Polymerase II Associated Factor 445.0 0 0 0 0 0.8164625614036873 P38351 0.9590039849281312 1.0 41.99203675348185 35.0 1.0 no 955 chrII_761645r 2988 high_effect YBR279W 391 - TTTCAACGATGTGTTATCAT L|136|F silent|TTG>TTA|L|136 silent|TCG>TCC|S|135 silent|TCG>TCA|S|135 PAF1 RNA Polymerase II Associated Factor 445.0 0 0 0 0 -0.3630234579253062 P38351 0.9587849974632264 0.2126622051000595 40.449640533720014 30.0 1.0 no 956 chrII_761856r 2993 high_effect YBR279W 602 - ATGCACTGCCCATGAATTTT A|207|P A|207|T S|206|T S|206|N PAF1 RNA Polymerase II Associated Factor 445.0 0 0 0 0 -0.5240078789975624 P38351 0.9573720097541808 0.9523990154266356 0.9512869715690612 0.9536849856376648 0.10785917192697524 0.022921545431017883 0.0 0.0 49.295410191989724 40.0 1.0 no 957 chrII_761926r 2995 high_effect YBR279W 672 - TCGTCTTCTTCCAGTTCCAC E|231|Q E|231|K D|230|H D|230|N PAF1 RNA Polymerase II Associated Factor 445.0 0 0 0 0 -0.517445903799232 P38351 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.05262714996933937 0.13486969470977786 0.1940135508775711 0.8797180652618408 56.459228922124616 50.0 1.0 no 958 chrII_762201 3001 high_effect YBR279W 944 + AAACGACATCATTAAACCTT N|316|K silent|AAC>AAT|N|316 D|317|E silent|GAC>GAT|D|317 PAF1 RNA Polymerase II Associated Factor 445.0 0 0 0 0 0.5593139398370138 P38351 0.9439849853515624 0.9532920122146606 0.6247106790542603 1.0 37.21011637293168 30.0 1.0 no 959 chrII_762243r 3002 high_effect YBR279W 989 - TTCTCAAAGTAACATTAAGT R|336|T R|336|K L|335|F silent|TTG>TTA|L|335 PAF1 RNA Polymerase II Associated Factor 445.0 0 0 0 0 0.38561734066333664 P38351 0.932735025882721 0.955805003643036 0.9587849974632264 0.016393039375543594 0.07196255773305893 0.035433080047368996 34.67430597870475 25.0 1.0 no 960 chrII_768297r 3006 high_effect YBR282W 60 - CCATCTCTGTATTTCTTCCA G|27|R G|27|S D|26|H D|26|N MRPL27 Mitochondrial Ribosomal Protein, Large subunit 146.0 0 0 0 0 0.04751967522261516 P36526 2.482599973678589 1.3032000064849854 3.4790000915527344 1.8550000190734863 52.07544129049808 40.0 1.0 no 961 chrII_768537 3014 high_effect YBR282W 297 + CCTCTAAAACACGAATTTAA L|101|V silent|CTA>TTA|L|101 P|100|R P|100|L MRPL27 Mitochondrial Ribosomal Protein, Large subunit 146.0 0 0 0 0 1.0713821429098775 P36526 0.7329952120780945 0.4620476961135864 0.2699228525161743 1.1131999492645264 1.1253999471664429 0.9828000068664552 35.59396761816953 30.0 1.0 no 962 chrII_779691 3016 high_effect YBR289W 24 + AACAGCGTTCCAAATAGTAT N|9|K silent|AAC>AAT|N|9 S|10|R silent|AGC>AGT|S|10 0 0 0 0 -0.1991652274905307 P18480 0.9439849853515624 0.9417110085487366 41.913217110504775 35.0 1.0 no 963 chrII_780531 3027 high_effect YBR289W 864 + ACCAATGTTCAGCCAACTAT silent|ACC>ACG|T|289 silent|ACC>ACT|T|289 T|289|S T|289|I 0 0 0 0 0.1578502523657841 P18480 0.9491789937019348 0.9472420215606691 0.7347686290740967 0.4358288943767548 47.314139648661296 40.0 1.0 no 964 chrII_780625 3028 high_effect YBR289W 958 + AGCTACCATATCCAACCTAT L|321|V silent|CTA>TTA|L|321 P|322|A P|322|S 0 0 0 0 0.015100849357604168 P18480 0.9512209892272948 0.9562489986419678 0.9498909711837769 0.0783964991569519 0.195943221449852 0.2972351014614105 49.209405159349615 40.0 1.0 no 965 chrII_780744 3031 high_effect YBR289W 1077 + TACGATCCGTTTAGCATTTA Y|360|* silent|TAC>TAT|Y|360 P|362|A P|362|S 0 0 0 0 -0.3825955236125596 P18480 0.9562489986419678 0.9498909711837769 0.0270318016409874 0.030015954747796062 45.08069558316515 35.0 1.0 no 966 chrII_780873r 3034 high_effect YBR289W 1209 - TTTCCCCAAATACTTGCCGA G|409|A G|409|E G|409|R G|409|R 0 0 0 0 -0.7636544483108173 P18480 0.9499930143356324 0.9438679814338684 0.941340982913971 0.941340982913971 0.0 0.0 0.0 0.0 51.53399177513803 45.0 1.0 no 967 chrII_780980r 3038 high_effect YBR289W 1316 - AGACTTTTAATTTATCCTCT V|445|L V|445|I 0 1 0 0 0.5939267473321981 P18480 0.9539830088615416 0.9574310183525084 0.9149282574653624 0.7391185760498047 40.77467168700122 25.0 1.0 no 968 chrII_781031 3040 high_effect YBR289W 1364 + ACAGTTAGTTCCCATAAGAT Q|456|E Q|456|* 0 0 0 0 -0.30573092876509284 P18480 0.9590039849281312 1.0 45.311952803949616 35.0 1.0 no 969 chrII_781082r 3042 high_effect YBR289W 1418 - TCCATAACAAAGTGTCCCTG W|479|S W|479|* W|479|C W|479|* 0 0 0 0 -0.9635846792924014 P18480 0.8858469724655151 0.8858469724655151 0.0022255945950746536 0.0015019540442153811 47.42671627427535 45.0 1.0 no 970 chrII_781163r 3043 high_effect YBR289W 1499 - CTCTCGTAGCGTCCTCAAAT R|506|T R|506|K silent|ACG>ACC|T|505 silent|ACG>ACA|T|505 0 0 0 0 0.2386474665340005 P18480 0.932735025882721 0.955805003643036 0.4931586980819702 1.0 51.22845060701035 50.0 1.0 no 971 chrII_781221 3044 high_effect YBR289W 1554 + GAGCAGATTCAGGAGTTTCA Q|520|E Q|520|* 0 0 0 0 -0.5138214485173832 P18480 0.9590039849281312 0.0 48.73053134126371 45.0 1.0 no 972 chrII_781248r 3046 high_effect YBR289W 1584 - TCCTGATTCAACTCTATATA Q|534|H silent|CAG>CAA|Q|534 D|535|H D|535|N 0 0 0 0 1.1904340656690604 P18480 0.9570760130882264 0.9486550092697144 0.956179976463318 0.18018700182437894 0.09782713651657103 0.519297182559967 41.47394392126319 30.0 1.0 no 973 chrII_781271r 3047 high_effect YBR289W 1607 - TCAAGTCATCACCGCCTAGA L|542|F silent|TTG>TTA|L|542 D|541|H D|541|N 0 0 0 0 1.26515946652599 P18480 0.9587849974632264 0.9486550092697144 0.956179976463318 0.1142742559313774 0.004409465007483959 0.008970994502305984 52.58562457663351 50.0 1.0 no 974 chrII_781331r 3048 high_effect YBR289W 1667 - ACTCAAATTGATCGATTAAC E|562|Q E|562|K E|562|D silent|GAG>GAA|E|562 0 0 0 0 1.4118866327960735 P18480 0.956179976463318 0.9475290179252625 0.94931298494339 0.011038145981729029 0.008577811531722546 0.060608815401792526 35.029203444633595 30.0 1.0 no 975 chrII_781556r 3053 high_effect YBR289W 1892 - CATCATCAAGAGTAATCGTT D|637|H D|637|N D|636|H D|636|N 0 0 0 0 -0.08329028991659126 P18480 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.016430232673883438 0.13809353113174438 0.11995478719472885 0.5022027492523193 40.388187119486076 35.0 1.0 no 976 chrII_781564 3055 high_effect YBR289W 1897 + TTACTCTTGATGATGTTTAT T|634|S T|634|I L|635|V L|635|F 0 0 0 0 0.2968363215228205 P18480 0.9491789937019348 0.9472420215606691 0.9512209892272948 0.9587849974632264 0.3584313690662384 0.06608863919973372 1.0 0.41663530468940735 38.88327269104372 25.0 1.0 no 977 chrII_781614r 3056 high_effect YBR289W 1950 - GCTGAAATCTGTAATAGGTT A|657|P A|657|T 0 0 0 0 0.0021562510039586247 P18480 0.9573720097541808 0.9523990154266356 0.3170899748802185 0.6124560236930847 40.76616016441909 35.0 1.0 no 978 chrIII_22648 3059 essential YCL059C 712 - TTCGACGTTTCTGATCTTCT E|244|Q E|244|K V|243|L V|243|I KRR1 contains KRR-R motif 316.0 0 0 0 0 -0.8804994863898059 P25586 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.4184235334396362 1.0 0.13912834227085116 0.1745179295539856 47.571334742884744 40.0 0.0 no 979 chrIII_22649 3060 essential YCL059C 711 - TCGACGTTTCTGATCTTCTT E|244|Q E|244|K V|243|L V|243|I KRR1 contains KRR-R motif 316.0 0 0 0 0 -0.4576508823465621 P25586 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.4184235334396362 1.0 0.13912834227085116 0.1745179295539856 47.5713347428848 40.0 0.0 no 980 chrIII_22684 3062 essential YCL059C 676 - CACATTCCTCTTCTTAAACA V|232|L V|232|M R|230|S silent|AGG>AGA|R|230 KRR1 contains KRR-R motif 316.0 0 0 0 0 0.5190486929109793 P25586 0.9539830088615416 0.9587630033493042 0.9087679982185364 1.0 0.2064274698495865 0.05938632041215896 43.51059532049732 35.0 0.0 no 981 chrIII_22685 3063 essential YCL059C 675 - ACATTCCTCTTCTTAAACAT V|232|L V|232|M R|230|S silent|AGG>AGA|R|230 KRR1 contains KRR-R motif 316.0 0 0 0 0 -0.5949642581319988 P25586 0.9539830088615416 0.9587630033493042 0.9087679982185364 1.0 0.2064274698495865 0.05938632041215896 42.19578973893885 30.0 0.0 no 982 chrIII_22773 3064 essential YCL059C 587 - ATTCCTTGATATGATAGATA E|202|Q E|202|K K|201|N silent|AAG>AAA|K|201 KRR1 contains KRR-R motif 316.0 0 0 0 0 0.3724042676092843 P25586 0.956179976463318 0.9475290179252625 0.9355990290641784 0.5369480848312378 0.6821274757385254 0.0 -0.09929519891738893 0.14612579345703125 0.3385761976242065 0.7695940136909485 38.32903555029594 25.0 0.0 no 983 chrIII_22809 3065 essential YCL059C 551 - TACAATCTTCTACTACTCGA C|190|S C|190|Y D|189|H D|189|N KRR1 contains KRR-R motif 316.0 0 0 0 0 -0.8023181462795553 P25586 0.9421560168266296 0.9290120005607604 0.9486550092697144 0.956179976463318 0.025441588833928108 0.002644588239490986 0.0031476449221372604 0.010550841689109802 -0.08202920109033585 11.735067367553713 -0.7798423767089844 -0.9697268009185792 41.6365446849461 35.0 0.0 no 984 chrIII_22917r 3068 essential YCL059C 440 + CCCTAACGGTAATACTTTAA P|148|R P|148|L P|148|A P|148|S KRR1 contains KRR-R motif 316.0 0 0 0 0 0.2259925916029623 P25586 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.008565069176256657 0.0036244024522602562 0.012493587099015713 0.08037137985229492 1.3187052011489868 1.3525214195251465 1.4303168058395386 1.5113341808319092 0.17678800225257876 -0.1368650197982788 0.16863799095153809 0.5809030532836914 41.67201814935596 35.0 0.0 no 985 chrIII_23010 3071 essential YCL059C 350 - CGCATGCCATGTCATCTTGT C|123|S C|123|Y A|122|P A|122|T KRR1 contains KRR-R motif 316.0 0 0 0 0 0.9815034955811308 P25586 0.9421560168266296 0.9290120005607604 0.9573720097541808 0.9523990154266356 0.2175516337156296 0.0012314493069425225 0.2333046644926071 0.4590996205806732 -0.4816559851169586 8.016139984130861 0.7903631925582886 -0.6526020169258118 54.651086749299104 50.0 0.0 no 986 chrIII_23258 3075 essential YCL059C 102 - AAACTGGACTCTTCAGCAAA S|40|T S|40|N KRR1 contains KRR-R motif 316.0 0 0 0 0 -0.2664974626653677 P25586 0.9512869715690612 0.9536849856376648 0.2036035507917404 0.009549967013299463 -0.4973979890346527 0.14515720307826996 41.800523918621884 40.0 0.0 no 987 chrIII_23330 3077 essential YCL059C 30 - TCAATATCATCCGTATCCCA D|17|H D|17|N KRR1 contains KRR-R motif 316.0 0 1 0 0 -0.780309151212017 P25586 0.9486550092697144 0.956179976463318 0.04538310691714287 0.11603079736232758 49.50035481641692 40.0 0.0 no 988 chrIII_31571 3080 essential YCL054W 122 + CCACTTCTTAGAAAAATCGA H|42|Q silent|CAC>CAT|H|42 H|42|D H|42|Y SPB1 Suppressor of PaB1 mutant 841.0 0 0 0 0 0.7539068296457891 P25582 0.9588389992713928 0.9473130106925964 0.9489949941635132 0.4214459955692291 0.3427586555480957 0.34579089283943176 38.68488486830921 35.0 1.0 no 989 chrIII_31653 3083 essential YCL054W 204 + CCTGTCAACTCCTTAATTAT P|69|R P|69|L silent|GTC>GTG|V|70 silent|GTC>GTT|V|70 SPB1 Suppressor of PaB1 mutant 841.0 0 0 0 0 1.1528090450996322 P25582 0.9432820081710817 0.9430609941482544 0.0151976328343153 0.005428474862128496 44.967958802990324 35.0 1.0 no 990 chrIII_31705r 3086 essential YCL054W 259 - ACTTTGAAAAGTTATAACAT S|93|T S|93|N SPB1 Suppressor of PaB1 mutant 841.0 0 0 0 0 -0.4191584477354168 P25582 0.9512869715690612 0.9536849856376648 0.16210679709911344 0.20940935611724854 31.49168522342484 20.0 1.0 no 991 chrIII_31885r 3088 essential YCL054W 439 - GTTCACCACCAAATTTTCGA silent|GTG>GTC|V|152 silent|GTG>GTA|V|152 V|152|L V|152|M SPB1 Suppressor of PaB1 mutant 841.0 0 0 0 0 0.004442159472263757 P25582 0.9539830088615416 0.9587630033493042 0.23799598217010495 0.08332792669534682 46.52539913684865 40.0 1.0 no 992 chrIII_31936r 3090 essential YCL054W 490 - AATCAATTTATTATAATCCT L|169|F silent|TTG>TTA|L|169 SPB1 Suppressor of PaB1 mutant 841.0 0 0 0 0 -0.8779818114783132 P25582 0.9587849974632264 0.0 33.30496442821618 15.0 1.0 no 993 chrIII_31919 3091 essential YCL054W 470 + TACTAAAATTTTCAGATCCA T|158|S T|158|I SPB1 Suppressor of PaB1 mutant 841.0 0 1 0 0 0.5143574301186419 P25582 0.9491789937019348 0.9472420215606691 0.0 0.0 36.687964674804284 25.0 1.0 no 994 chrIII_31967r 3092 essential YCL054W 521 - CAACTTTCTCAAACAATTGT V|180|L V|180|I SPB1 Suppressor of PaB1 mutant 841.0 0 0 0 0 1.053819351513508 P25582 0.9539830088615416 0.9574310183525084 0.0 0.0 37.275607843194905 30.0 1.0 no 995 chrIII_32005r 3095 essential YCL054W 559 - TGCAGAAACATTTCTTGATG A|193|P A|193|T SPB1 Suppressor of PaB1 mutant 841.0 0 0 0 0 -0.2727918805245987 P25582 0.9573720097541808 0.9523990154266356 0.0 0.0 39.10848521533524 35.0 1.0 no 996 chrIII_32115r 3100 essential YCL054W 669 - TCCATATTCTGTTGCCCATC M|229|I M|229|I E|230|Q E|230|K SPB1 Suppressor of PaB1 mutant 841.0 0 0 0 0 -1.4049582958170963 P25582 0.9553959965705872 0.9553959965705872 0.956179976463318 0.9475290179252625 0.3618353605270386 0.3618353605270386 0.4989060461521149 0.6488618850708008 54.48855180455541 45.0 1.0 no 997 chrIII_32218 3101 essential YCL054W 769 + CCTCAATTTTGGATTTTGTC S|258|* S|258|L silent|ACC>ACG|T|257 silent|ACC>ACT|T|257 SPB1 Suppressor of PaB1 mutant 841.0 0 0 0 0 0.2247228108738513 P25582 0.9298099875450134 0.3574244976043701 44.31690472665906 35.0 1.0 no 998 chrIII_32335r 3104 essential YCL054W 889 - ACAGGAACGGAACTCGTCTG C|303|S C|303|Y SPB1 Suppressor of PaB1 mutant 841.0 0 0 0 0 -0.1596322912196345 P25582 0.9421560168266296 0.9290120005607604 0.5574010014533997 0.3994162082672119 46.553956214057386 55.00000000000001 1.0 no 999 chrIII_32300r 3105 essential YCL054W 854 - TCTTCAAGATCTTCCATTCA K|291|N silent|AAG>AAA|K|291 L|290|F silent|TTG>TTA|L|290 SPB1 Suppressor of PaB1 mutant 841.0 0 0 0 0 -1.0095858035670684 P25582 0.9355990290641784 0.9587849974632264 0.3950199484825134 0.11387160420417786 46.16253337729705 35.0 1.0 no 1000 chrIII_32353r 3106 essential YCL054W 907 - GACTTTTAAATCTTCAATAC V|309|L V|309|I SPB1 Suppressor of PaB1 mutant 841.0 0 0 0 0 0.2314395995416345 P25582 0.9539830088615416 0.9574310183525084 0.0 0.0 33.85973554624752 25.0 1.0 no 1001 chrIII_32402r 3107 essential YCL054W 956 - TTGCAATCTTTCTCCATCTT A|325|P A|325|T SPB1 Suppressor of PaB1 mutant 841.0 0 0 0 0 0.2177086887777409 P25582 0.9573720097541808 0.9523990154266356 0.03254062309861183 0.11208321154117584 48.392313033836096 35.0 1.0 no 1002 chrIII_32620r 3109 essential YCL054W 1174 - TTCAATACCAATATCAGTGG E|398|Q E|398|K SPB1 Suppressor of PaB1 mutant 841.0 0 0 0 0 -0.7999496645779094 P25582 0.956179976463318 0.9475290179252625 0.01439753733575344 0.011148946359753607 40.59526866500824 35.0 1.0 no 1003 chrIII_32693 3111 essential YCL054W 1244 + GACTGGTATCTTGAACGACT T|416|S T|416|I SPB1 Suppressor of PaB1 mutant 841.0 0 0 0 0 1.3022564167136332 P25582 0.9491789937019348 0.9472420215606691 0.7312198877334595 0.18535593152046204 44.950087910455295 45.0 1.0 no 1004 chrIII_32699 3112 essential YCL054W 1250 + TATCTTGAACGACTTGGCGA I|418|M silent|ATC>ATT|I|418 SPB1 Suppressor of PaB1 mutant 841.0 0 0 0 0 0.3866028798480789 P25582 0.9598389863967896 0.10816715657711028 45.261607865287196 45.0 1.0 no 1005 chrIII_32893r 3115 essential YCL054W 1447 - TGCTTGCTTAGCTCTAAACT A|489|P A|489|T K|487|N silent|AAG>AAA|K|487 SPB1 Suppressor of PaB1 mutant 841.0 0 0 0 0 -0.7421690386715367 P25582 0.9573720097541808 0.9523990154266356 0.9355990290641784 0.1252005398273468 0.3019713759422302 0.010296759195625782 47.17514048827086 40.0 1.0 no 1006 chrIII_33055r 3117 essential YCL054W 1609 - CTTCAATTTGCTAATCAAAT L|542|F silent|TTG>TTA|L|542 SPB1 Suppressor of PaB1 mutant 841.0 0 0 0 0 0.09702817081878642 P25582 0.9587849974632264 0.07218434661626816 35.790425614074024 25.0 1.0 no 1007 chrIII_33172r 3121 essential YCL054W 1726 - ACTCATTATGCCATCATTGA M|581|I M|581|I S|582|T S|582|N SPB1 Suppressor of PaB1 mutant 841.0 0 0 0 0 -0.6024984243082114 P25582 0.9553959965705872 0.9553959965705872 0.9512869715690612 0.9536849856376648 0.13920876383781433 0.13920876383781433 0.5004004836082458 0.4533675611019135 46.05497117477501 35.0 1.0 no 1008 chrIII_34482 3122 essential YCL052C 892 - TGTCACTTCATTCATTGTGC silent|GTG>GTC|V|303 silent|GTG>GTA|V|303 V|303|L V|303|M 0 0 0 1 -0.1897063835846634 P25580 0.9454690217971802 0.9559720158576964 0.1915108412504196 0.01266392320394516 48.14486501366542 40.0 0.0 no 1009 chrIII_35028 3132 essential YCL052C 346 - TGACAGATTCAAATCTACTT silent|CTG>CTC|L|121 silent|CTG>CTA|L|121 0 0 0 0 0.19060045141833834 P25580 37.81567267912391 30.0 0.0 no 1010 chrIII_35029 3133 essential YCL052C 345 - GACAGATTCAAATCTACTTC silent|CTG>CTC|L|121 silent|CTG>CTA|L|121 0 0 0 0 0.4159000214633636 P25580 38.649332139888884 35.0 0.0 no 1011 chrIII_35132r 3136 essential YCL052C 239 + TTCAGTTTACTCAAATTCTT S|81|* S|81|L 0 1 0 0 0.9148488657314972 P25580 0.9753659963607788 0.012793948873877524 38.950232638190926 25.0 0.0 no 1012 chrIII_35296r 3143 essential YCL052C 75 + ACTCATTTGACTGTTCGTGG H|27|D H|27|Y T|26|S T|26|I 0 1 0 0 1.3945768412741455 P25580 0.9917020201683044 0.9918540120124816 0.9913139939308168 0.9893620014190674 0.07185269892215729 0.017810562625527382 0.1975744515657425 0.04110177606344223 47.78947257623923 45.0 0.0 no 1013 chrIII_35299r 3144 essential YCL052C 72 + GACACTCATTTGACTGTTCG D|25|E silent|GAC>GAT|D|25 T|26|S T|26|I 0 1 0 0 -0.6065171653245218 P25580 0.9954699873924256 0.9913139939308168 0.9893620014190674 0.2919847071170807 0.1975744515657425 0.04110177606344223 45.75093697780829 45.0 0.0 no 1014 chrIII_49074r 3149 essential YCL043C 1125 + TCCTCTGTCTTCCAATTGGT silent|TCC>TCG|S|376 silent|TCC>TCT|S|376 S|376|C S|376|F PDI1 Protein Disulfide Isomerase 522.0 0 0 0 0 1.1505094561590163 P17967 0.945252001285553 0.9294660091400146 0.0119347982108593 0.010730628855526449 0.1926800012588501 0.13322000205516815 54.576174095935755 45.0 0.0 no 1015 chrIII_49113 3150 essential YCL043C 1089 - ATCTCTTGGGACTTCACGAT E|369|D silent|GAG>GAA|E|369 E|369|Q E|369|K PDI1 Protein Disulfide Isomerase 522.0 0 0 0 0 0.5805161208553783 P17967 0.94931298494339 0.956179976463318 0.9475290179252625 0.4899960458278656 0.2298706769943237 0.18309178948402405 0.3111000061035156 -0.09458000212907793 -0.10976000130176544 48.86058200358564 45.0 0.0 no 1016 chrIII_49115 3151 essential YCL043C 1087 - CTCTTGGGACTTCACGATTG E|369|Q E|369|K PDI1 Protein Disulfide Isomerase 522.0 0 0 0 0 0.4901132822475505 P17967 0.956179976463318 0.9475290179252625 0.2298706769943237 0.18309178948402405 -0.09458000212907793 -0.10976000130176544 48.05207575089162 50.0 0.0 no 1017 chrIII_49114 3152 essential YCL043C 1088 - TCTCTTGGGACTTCACGATT E|369|Q E|369|K E|369|D silent|GAG>GAA|E|369 PDI1 Protein Disulfide Isomerase 522.0 0 0 0 0 -0.12436412758813856 P17967 0.956179976463318 0.9475290179252625 0.94931298494339 0.2298706769943237 0.18309178948402405 0.4899960458278656 -0.09458000212907793 -0.10976000130176544 0.3111000061035156 49.14943041134347 45.0 0.0 no 1018 chrIII_49420r 3162 essential YCL043C 779 + TTACTTATTCTACAATGACG Y|261|* silent|TAC>TAT|Y|261 PDI1 Protein Disulfide Isomerase 522.0 0 0 0 0 -0.0408601107981672 P17967 36.86047208940107 30.0 0.0 no 1019 chrIII_49484 3168 essential YCL043C 718 - ACCGTCGATTTCACCAAAGT G|246|R G|246|S G|246|A G|246|D PDI1 Protein Disulfide Isomerase 522.0 0 0 0 0 0.17810806055645467 P17967 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.21471227705478668 0.4926782548427582 0.986220121383667 0.21394045650959012 -0.3616200089454651 -0.07649999856948853 -0.2612000107765198 0.13255999982357025 1.0432000160217283 1.4670000076293943 -0.19699999690055847 3.715800046920776 48.32101294721252 45.0 0.0 no 1020 chrIII_49485 3169 essential YCL043C 717 - CCGTCGATTTCACCAAAGTA G|246|R G|246|S D|245|H D|245|N PDI1 Protein Disulfide Isomerase 522.0 0 0 0 0 -0.967075962636662 P17967 0.941340982913971 0.951104998588562 0.9486550092697144 0.956179976463318 0.21471227705478668 0.4926782548427582 0.05739530175924301 1.0 -0.3616200089454651 -0.07649999856948853 2.0591399669647217 0.8618199825286865 1.0432000160217283 1.4670000076293943 -0.9333999752998352 0.0575999990105629 47.39475813290329 45.0 0.0 no 1021 chrIII_49563 3172 essential YCL043C 639 - TTCTTACCGTTGTATACTAC K|219|N silent|AAG>AAA|K|219 G|218|A G|218|D PDI1 Protein Disulfide Isomerase 522.0 0 0 0 0 1.6418070364764152 P17967 0.9355990290641784 0.9499930143356324 0.9446240067481996 0.2788476049900055 0.21259312331676486 0.18062688410282132 0.0837400034070015 -0.3280999958515167 0.08736000210046768 0.6855999827384949 43.86147808809335 35.0 0.0 no 1022 chrIII_49681r 3178 essential YCL043C 518 + CAACGCCACCTTTTACTCCA N|174|K silent|AAC>AAT|N|174 A|175|G A|175|V PDI1 Protein Disulfide Isomerase 522.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.3017363958292283 P17967 0.9439849853515624 0.9484469890594482 0.9504740238189696 0.0 0.13263922929763794 0.10143399238586426 -0.2590999901294708 0.4898999929428101 0.20173999667167666 0.4343999922275543 0.09933999925851822 53.41453404017784 50.0 0.0 no 1023 chrIII_49722r 3180 essential YCL043C 477 + ACTCCAGTTATCGTCCAATC P|161|A P|161|S T|160|S T|160|I PDI1 Protein Disulfide Isomerase 522.0 0 0 0 0 0.19258223944017847 P17967 0.9562489986419678 0.9498909711837769 0.9491789937019348 0.9472420215606691 0.9223297834396362 0.852812647819519 0.878312885761261 0.3198210895061493 2.636620044708252 4.697979927062988 0.6491400003433228 -0.028899999335408214 2.1052000522613525 3.2980000972747803 0.0843999981880188 -1.246999979019165 50.341205508031244 45.0 0.0 no 1024 chrIII_49852r 3188 essential YCL043C 347 + TAACAACTCGATCGATTACG N|117|K silent|AAC>AAT|N|117 N|118|K silent|AAC>AAT|N|118 PDI1 Protein Disulfide Isomerase 522.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.363166792760069 P17967 0.9439849853515624 0.9439849853515624 0.8589611053466797 0.948078155517578 -0.6246600151062012 -0.6689599752426147 -1.0368000268936155 38.712484426848334 40.0 0.0 no 1025 chrIII_49851r 3189 essential YCL043C 348 + AACAACTCGATCGATTACGA N|117|K silent|AAC>AAT|N|117 N|118|K silent|AAC>AAT|N|118 PDI1 Protein Disulfide Isomerase 522.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.01785394537367238 P17967 0.9439849853515624 0.9439849853515624 0.8589611053466797 0.948078155517578 -0.6246600151062012 -0.6689599752426147 -1.0368000268936155 40.252028811941564 40.0 0.0 no 1026 chrIII_49893 3190 essential YCL043C 309 - ATCTTCAAGCTTGGGAACCC K|109|N silent|AAG>AAA|K|109 L|108|F silent|TTG>TTA|L|108 PDI1 Protein Disulfide Isomerase 522.0 0 1 0 0 -0.9237848243720488 P17967 0.9355990290641784 0.9587849974632264 0.0 0.028573479503393177 0.04795999825000763 4.846059799194336 51.29580246814918 50.0 0.0 no 1027 chrIII_49995 3191 essential YCL043C 207 - TCGGCGGCTTTAACGTATTC E|76|Q E|76|K A|75|P A|75|T PDI1 Protein Disulfide Isomerase 522.0 0 0 0 0 -1.232759412561531 P17967 0.956179976463318 0.9475290179252625 0.9573720097541808 0.9523990154266356 0.218888521194458 0.3918624818325043 0.0 0.0 -0.3470999896526337 -0.6175199747085571 7.266079902648926 3.0032401084899902 9.748820304870604 1.8722399473190308 49.61911953179747 50.0 0.0 no 1028 chrIII_50025 3193 essential YCL043C 177 - TTCTTACAGTGGCCACACCA K|65|N silent|AAG>AAA|K|65 C|64|S C|64|Y PDI1 Protein Disulfide Isomerase 522.0 0 1 0 0 -0.7002421327468965 P17967 0.9355990290641784 0.9421560168266296 0.9290120005607604 0.0 0.3593630492687225 0.007857794873416424 1.8218799829483032 1.6066399812698364 35.88610076904297 1.4950400590896606 37.649818420410156 54.97197158316726 50.0 0.0 no 1029 chrIII_50068r 3195 essential YCL043C 131 + GTACATTCAGTCGCACGACT Y|45|* silent|TAC>TAT|Y|45 PDI1 Protein Disulfide Isomerase 522.0 0 0 0 0 -1.018427368278196 P17967 50.42267202665369 50.0 0.0 no 1030 chrIII_50078 3196 essential YCL043C 124 - CGACTGAATGTACTCATTGA Q|47|H silent|CAG>CAA|Q|47 PDI1 Protein Disulfide Isomerase 522.0 0 0 0 0 -0.2319549474697068 P17967 0.9570760130882264 0.07969747483730316 0.8289999961853027 0.003000000026077032 41.71106413374258 40.0 0.0 no 1031 chrIII_50116 3198 essential YCL043C 86 - TAACGACAGCGGAGTCTTCA V|35|L V|35|I V|34|L V|34|I PDI1 Protein Disulfide Isomerase 522.0 0 0 0 0 -1.5104572459844932 P17967 0.9539830088615416 0.9574310183525084 0.9539830088615416 0.9574310183525084 0.04124882444739342 0.33942729234695435 0.0 0.0 0.25839999318122864 0.06390000134706497 2.592159986495972 1.5286999940872192 -0.1928199976682663 -0.08073999732732773 2.4880800247192383 1.4418200254440308 48.18047718985872 50.0 0.0 no 1032 chrIII_50162 3203 essential YCL043C 40 - AACAGAGGAGGCGAGCAGCA V|20|L V|20|I PDI1 Protein Disulfide Isomerase 522.0 0 0 0 0 -0.2865430867032574 P17967 0.9539830088615416 0.9574310183525084 0.8194443583488464 0.534485399723053 52.88347264305088 60.0 0.0 no 1033 chrIII_50189r 3205 essential YCL043C 10 + CTGCTGGTGCCGTCCTGTCA A|5|G A|5|V PDI1 Protein Disulfide Isomerase 522.0 0 0 0 0 -0.5290864229064425 P17967 0.9484469890594482 0.9504740238189696 0.36408883333206177 0.3046771585941315 64.61117593454713 65.0 0.0 no 1034 chrIII_65027 3208 essential YCL031C 522 - TTCAAATAATCAATATCCAG L|180|F silent|TTG>TTA|L|180 RRP7 Ribosomal RNA Processing 297.0 0 0 0 0 0.2009029119669584 P25368 0.033491335809230804 0.10891559720039368 2.6175999641418457 33.893751721589645 25.0 0.0 no 1035 chrIII_65155r 3209 essential YCL031C 391 + CTGCAAGTATAAATAACTGC A|132|G A|132|V RRP7 Ribosomal RNA Processing 297.0 0 0 0 0 -0.6239468649431477 P25368 0.19869232177734372 0.061339646577835076 0.6179075837135315 0.4811860024929047 37.19214275358172 35.0 0.0 no 1036 chrIII_65407 3216 essential YCL031C 142 - AAACAAACAGTCAGACTCGT L|53|F silent|TTG>TTA|L|53 RRP7 Ribosomal RNA Processing 297.0 0 0 0 0 0.308774088694315 P25368 0.02314992249011993 2.026498794555664 40.09808397861394 40.0 0.0 no 1037 chrIII_65496r 3218 essential YCL031C 50 + GTTCAAATTACCGGATCACA F|18|L silent|TTC>TTT|F|18 RRP7 Ribosomal RNA Processing 297.0 0 0 0 0 -0.2529743078506124 P25368 0.5145291686058044 2.048474073410034 44.17271744868884 40.0 0.0 no 1038 chrIII_93231 3222 essential YCL017C 1020 - TCACCAAATCCCGCTACCAA G|346|A G|346|D E|347|Q E|347|K NFS1 NiFS-like 497.0 0 0 0 0 -1.385960741071557 P25374 0.6328570246696472 0.5488979816436768 0.8769729733467102 0.8291500210762024 0.1935919374227524 0.001311180298216641 0.18710198998451236 0.8803192377090454 51.847420770469284 50.0 0.0 no 1039 chrIII_93358r 3230 essential YCL017C 890 + TCACAAGATTTACGGTCCAA H|298|Q silent|CAC>CAT|H|298 H|298|D H|298|Y NFS1 NiFS-like 497.0 0 0 0 0 1.0528705635018187 P25374 0.6223030090332031 0.6270779967308044 0.6290119886398315 0.0013999727088958025 0.0046516964212059975 0.0008104568696580827 44.23369125500442 40.0 0.0 no 1040 chrIII_93428 3232 essential YCL017C 823 - AATCTTACCATAGGCTTGTG K|280|N silent|AAG>AAA|K|280 NFS1 NiFS-like 497.0 0 0 0 0 -1.6374780950302008 P25374 0.6809970140457153 0.031737811863422394 -0.4004000127315521 45.97902806618885 40.0 0.0 no 1041 chrIII_93632 3235 essential YCL017C 619 - TTCAAATCCCTCCTTCATCA E|213|Q E|213|K NFS1 NiFS-like 497.0 0 0 0 0 0.3902868190527956 P25374 0.9392210245132446 0.914098024368286 0.1137024536728859 0.2774829268455505 50.579818218607045 40.0 0.0 no 1042 chrIII_93748r 3240 essential YCL017C 500 + AGCGACCGAATCTAATAATA A|168|G A|168|V T|169|S T|169|I NFS1 NiFS-like 497.0 0 0 0 0 -2.2630397977576955 P25374 0.6501309871673584 0.6235629916191101 0.6616600155830383 0.6859859824180603 0.35697171092033386 0.003415377577766776 0.1369686722755432 0.0008867593714967369 1.0772000551223757 -0.5267999768257141 39.39067301646844 35.0 0.0 yes 1043 chrIII_93916 3244 essential YCL017C 335 - ACATCGTATCCAAAACCCTA M|118|I M|118|I silent|ACG>ACC|T|117 silent|ACG>ACA|T|117 NFS1 NiFS-like 497.0 0 0 0 0 -0.8895828809929082 P25374 0.8721529841423035 0.8721529841423035 0.022234268486499783 0.022234268486499783 0.08479999750852585 0.08479999750852585 45.97019445415515 40.0 0.0 no 1044 chrIII_93932r 3248 essential YCL017C 316 + CCACTACACCAACAGACCCT T|107|S T|107|I silent|GCC>GCG|A|106 silent|GCC>GCT|A|106 NFS1 NiFS-like 497.0 0 0 0 0 0.6163436059346412 P25374 0.8090819716453552 0.5819730162620544 0.029883671551942825 0.0007458889158442616 -2.5053999423980717 0.8669999837875366 53.9834884611455 55.00000000000001 0.0 no 1045 chrIII_93931r 3249 essential YCL017C 317 + CACTACACCAACAGACCCTA T|107|S T|107|I T|108|R T|108|I NFS1 NiFS-like 497.0 0 0 0 0 -0.3048302246731866 P25374 0.8090819716453552 0.5819730162620544 0.5540890097618103 0.7413619756698608 0.029883671551942825 0.0007458889158442616 0.0008476003422401844 0.0009116323781199752 -2.5053999423980717 0.8669999837875366 50.07224749738202 50.0 0.0 no 1046 chrIII_93857 3250 essential YCL017C 394 - CCAACCGTAAGAGTGAGTGT W|138|S W|138|* G|137|A G|137|D NFS1 NiFS-like 497.0 0 0 0 0 -4.251828003079959 P25374 0.6943100094795227 0.6383789777755737 0.5837669968605042 0.17989720404148102 0.03719348832964897 0.0008810758590698242 1.2148000001907349 48.86163171708597 50.0 0.0 yes 1047 chrIII_93984r 3252 essential YCL017C 264 + TATCAAGAAAACACAGGTTT Q|90|E Q|90|* NFS1 NiFS-like 497.0 0 0 0 0 -0.3944636897947316 P25374 1.0237799882888794 35.670846798857845 30.0 0.0 no 1048 chrIII_94144 3260 essential YCL017C 107 - ACTTCACGCCTGCTGCAGGA K|42|N silent|AAG>AAA|K|42 silent|GTG>GTC|V|41 silent|GTG>GTA|V|41 NFS1 NiFS-like 497.0 0 0 0 0 -0.3031803843225301 P25374 1.0028899908065796 58.95102923979431 60.0 0.0 no 1049 chrIII_95069 3265 high_effect YCL016C 675 - TCAATGATTTCTCTTGTGTA E|232|Q E|232|K DCC1 Defective in sister Chromatid Cohesion 380.0 0 0 0 0 1.0801852627040918 P25559 0.31168466806411743 0.7107964158058167 41.895249799134774 30.0 0.0 no 1050 chrIII_95136r 3268 high_effect YCL016C 605 + TCTACAGCATCTGAATGTTG L|203|V silent|CTA>TTA|L|203 Q|204|E Q|204|* DCC1 Defective in sister Chromatid Cohesion 380.0 0 0 0 0 -1.0764571666214775 P25559 0.3383998572826385 0.9684226512908936 43.47986300181879 40.0 0.0 no 1051 chrIII_95305 3272 high_effect YCL016C 439 - GTTCTCAAGTAGTTCTTCCA E|152|D silent|GAG>GAA|E|152 E|152|Q E|152|K DCC1 Defective in sister Chromatid Cohesion 380.0 0 0 0 0 -0.2837189136199452 P25559 0.5844939351081848 0.32433342933654785 0.4044515788555145 50.30454479947496 40.0 0.0 no 1052 chrIII_95347 3275 high_effect YCL016C 397 - TGACCTCTTCATGATTTTGT R|138|S silent|AGG>AGA|R|138 R|138|T R|138|K DCC1 Defective in sister Chromatid Cohesion 380.0 0 0 0 0 -0.5237674244112579 P25559 46.47043892878725 35.0 0.0 no 1053 chrIII_95375 3276 high_effect YCL016C 369 - TCCAGTTCTCCGTTGTATAT silent|CTG>CTC|L|129 silent|CTG>CTA|L|129 D|130|H D|130|N DCC1 Defective in sister Chromatid Cohesion 380.0 0 0 0 0 0.4723311076797571 P25559 51.589143542836844 40.0 0.0 no 1054 chrIII_95376r 3277 high_effect YCL016C 365 + ACCAATATACAACGGAGAAC P|123|R P|123|L P|123|A P|123|S DCC1 Defective in sister Chromatid Cohesion 380.0 0 0 0 0 0.7335699415625421 P25559 0.02062525413930416 0.014769928529858591 0.06787785887718199 0.06522869318723679 38.68477287673488 40.0 0.0 no 1055 chrIII_95437 3278 high_effect YCL016C 307 - CTCAAATTCTGATTCAGTCT E|109|Q E|109|K DCC1 Defective in sister Chromatid Cohesion 380.0 0 0 0 0 0.056277090577297316 P25559 0.0 0.0 42.409826641740544 35.0 0.0 no 1056 chrIII_95495r 3281 high_effect YCL016C 246 + TTCGACGAAACGCTCTTGTT F|83|L silent|TTC>TTT|F|83 D|84|E silent|GAC>GAT|D|84 DCC1 Defective in sister Chromatid Cohesion 380.0 0 0 0 0 -0.21385011583187089 P25559 0.46910759806633 1.0 45.63868654717726 45.0 0.0 no 1057 chrIII_95637r 3284 high_effect YCL016C 104 + CCAGTTAAGGTTTAAGTCAT Q|36|E Q|36|* DCC1 Defective in sister Chromatid Cohesion 380.0 0 0 0 0 -1.5714925141606284 P25559 0.9921339154243468 43.418653797896745 35.0 0.0 no 1058 chrIII_109198 3289 essential YCL004W 93 + GCTGCGAACCCTTCTCCATT A|32|G A|32|V A|33|G A|33|V PGS1 PhosphatidylGlycerolphosphate Synthase 521.0 0 0 0 0 -0.35404753478419904 P25578 0.9484469890594482 0.9504740238189696 0.9484469890594482 0.9504740238189696 0.4179718494415283 0.30946817994117737 0.4156557023525238 0.2612995803356171 57.89057781822237 55.00000000000001 1.0 no 1059 chrIII_109476r 3293 essential YCL004W 374 - GCAATTCTCTTGTTCCTCGA L|131|F silent|TTG>TTA|L|131 E|130|Q E|130|K PGS1 PhosphatidylGlycerolphosphate Synthase 521.0 0 0 0 0 0.3364970457663565 P25578 0.9587849974632264 0.956179976463318 0.9475290179252625 0.05438913032412529 0.0 0.0 51.80170646764492 45.0 1.0 no 1060 chrIII_109525 3295 essential YCL004W 420 + TCGTCTTTAGTAGCCAAATA S|141|W S|141|L S|142|C S|142|F PGS1 PhosphatidylGlycerolphosphate Synthase 521.0 0 0 0 0 1.0065869178901914 P25578 0.9288619756698608 0.9298099875450134 0.945252001285553 0.9294660091400146 0.0014254162088036535 0.013479532673954964 0.010827819816768171 0.0063433945178985604 44.03980562036411 35.0 1.0 no 1061 chrIII_109538r 3297 essential YCL004W 436 - CACTCTCTCTGACCCATATT V|152|L V|152|M R|151|T R|151|K PGS1 PhosphatidylGlycerolphosphate Synthase 521.0 0 0 0 0 -0.7069635316716001 P25578 0.9539830088615416 0.9587630033493042 0.932735025882721 0.955805003643036 0.021793277934193608 0.004288611002266407 0.0 0.0 51.667406729976044 45.0 1.0 no 1062 chrIII_109612 3302 essential YCL004W 507 + GTTCCCAAGAGATTTAATGA P|171|A P|171|S P|171|R P|171|L PGS1 PhosphatidylGlycerolphosphate Synthase 521.0 0 0 0 0 -1.0211067007013763 P25578 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.0 0.0 0.0 0.0 42.70713806348863 35.0 1.0 no 1063 chrIII_109615r 3303 essential YCL004W 513 - AAACCTTCATTAAATCTCTT G|177|A G|177|D G|177|R G|177|S PGS1 PhosphatidylGlycerolphosphate Synthase 521.0 0 0 0 0 0.5101165338957917 P25578 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.31573814153671265 0.06780677288770676 0.05092522501945496 0.17215825617313385 37.73875279848738 25.0 1.0 no 1064 chrIII_109855r 3304 essential YCL004W 753 - TCAACAGTAGGATTCGAATC E|258|Q E|258|K V|257|L V|257|I PGS1 PhosphatidylGlycerolphosphate Synthase 521.0 0 0 0 0 -0.6578639099487209 P25578 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.2322475612163544 0.20625828206539154 0.3809472620487213 0.26336202025413513 40.63756471243392 40.0 1.0 no 1065 chrIII_110026r 3308 essential YCL004W 924 - GTCGATTTGTCATTATATTT silent|TCG>TCC|S|314 silent|TCG>TCA|S|314 PGS1 PhosphatidylGlycerolphosphate Synthase 521.0 0 0 0 0 -0.4631559633359214 P25578 39.98659181559884 25.0 1.0 no 1066 chrIII_110208 3313 essential YCL004W 1103 + AAACGGCTTTTACCAATCAA N|369|K silent|AAC>AAT|N|369 silent|GGC>GGG|G|370 silent|GGC>GGT|G|370 PGS1 PhosphatidylGlycerolphosphate Synthase 521.0 0 0 0 0 -0.8728863906361772 P25578 0.9439849853515624 0.0 41.247312624631384 35.0 1.0 no 1067 chrIII_131025 3317 high_effect YCR009C 498 - CTCAATTCTTTTTCAGCCCT L|172|F silent|TTG>TTA|L|172 RVS161 Reduced Viability on Starvation 265.0 0 1 0 0 0.9760171929504496 P25343 0.9587849974632264 0.7332947850227356 5.347539901733398 51.56651587313087 40.0 0.0 no 1068 chrIII_131036 3318 high_effect YCR009C 487 - TTCAGCCCTTGGCAGTTTAG E|169|Q E|169|K A|168|P A|168|T RVS161 Reduced Viability on Starvation 265.0 0 1 0 0 -0.2051328888967729 P25343 0.956179976463318 0.9475290179252625 0.9573720097541808 0.9523990154266356 0.1887722909450531 0.014642412774264812 0.018451899290084842 0.01711932010948658 5.64192008972168 1.6129200458526611 55.77518084721589 50.0 0.0 no 1069 chrIII_131166 3322 high_effect YCR009C 357 - TACGTCGAAAACTTTGTTAT silent|ACG>ACC|T|125 silent|ACG>ACA|T|125 silent|TCG>TCC|S|124 silent|TCG>TCA|S|124 RVS161 Reduced Viability on Starvation 265.0 0 0 0 0 0.12881202074704012 P25343 37.38509725887377 30.0 0.0 no 1070 chrIII_131190 3324 high_effect YCR009C 333 - TCTAGTACGGTTTCTCTTAA D|118|H D|118|N RVS161 Reduced Viability on Starvation 265.0 0 0 0 0 0.0005729855715578824 P25343 0.9486550092697144 0.956179976463318 0.04102540761232376 0.5003860592842102 44.413071692263095 35.0 0.0 no 1071 chrIII_131213r 3325 high_effect YCR009C 307 + AAACTGTTAAGCAATTAGAC T|104|S T|104|I RVS161 Reduced Viability on Starvation 265.0 0 1 0 0 0.15113279664133766 P25343 0.9491789937019348 0.9472420215606691 0.5153236389160156 0.4401922225952149 34.568448359525746 30.0 0.0 no 1072 chrIII_137856r 3333 essential YCR012W 113 - GCAAAGCAGCAACAATTCTT L|44|F silent|TTG>TTA|L|44 A|43|P A|43|T PGK1 3-PhosphoGlycerate Kinase 416.0 0 1 0 0 -0.959513835975902 P00560 0.00815636944025755 0.0062684244476258755 0.15589073300361633 2.076780080795288 2.9578800201416016 1.4335399866104126 43.30294729238 40.0 1.0 no 1073 chrIII_137877 3334 essential YCR012W 131 + GCCAACCATCAAGTACGTTT P|45|R P|45|L P|45|A P|45|S PGK1 3-PhosphoGlycerate Kinase 416.0 0 1 0 0 0.1220050051457272 P00560 0.0013874339638277886 0.0012253756867721677 0.007046256680041552 0.03673611208796501 0.3190799951553345 0.4911800026893616 1.3240200281143188 1.943560004234314 49.356021597785684 45.0 1.0 no 1074 chrIII_137907r 3337 essential YCR012W 164 - AAGCCAAGACAACGTATCTT A|61|P A|61|T L|60|F silent|TTG>TTA|L|60 PGK1 3-PhosphoGlycerate Kinase 416.0 0 0 0 0 0.2419321183058384 P00560 0.14338184893131256 0.3654773235321045 0.005458476021885872 4.911280155181885 0.7204999923706055 4.997379779815674 43.35854457126368 40.0 1.0 no 1075 chrIII_137970 3339 essential YCR012W 224 + CTCTTTGGCTCCAGTTGCTA S|76|C S|76|F PGK1 3-PhosphoGlycerate Kinase 416.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.8371886598504141 P00560 0.0034210155718028545 0.002220902591943741 1.0415199995040894 6.24015998840332 57.007485900605566 50.0 1.0 no 1076 chrIII_138061 3341 essential YCR012W 315 + GCTGTCAAGGCTTCTGCCCC A|106|G A|106|V silent|GTC>GTG|V|107 silent|GTC>GTT|V|107 PGK1 3-PhosphoGlycerate Kinase 416.0 0 1 0 0 -0.4611937364819999 P00560 0.11985044181346892 0.15366144478321075 1.2862000465393066 0.4973399937152863 64.51698216784217 65.0 1.0 no 1077 chrIII_138078 3343 essential YCR012W 332 + CCCAGGTTCCGTTATTTTGT P|112|R P|112|L P|112|A P|112|S PGK1 3-PhosphoGlycerate Kinase 416.0 0 1 0 0 0.17865787256072813 P00560 0.3843642473220825 0.22120043635368347 0.6228227615356445 0.5379914045333862 1.0850600004196167 1.1184200048446655 0.9688000082969666 1.2309000492095947 55.064223537897355 45.0 1.0 no 1078 chrIII_138078r 3344 essential YCR012W 335 - CCAACAAAATAACGGAACCT L|118|F silent|TTG>TTA|L|118 L|117|F silent|TTG>TTA|L|117 PGK1 3-PhosphoGlycerate Kinase 416.0 0 1 0 0 1.018122127326076 P00560 0.004287330433726311 0.006045325193554163 3.827579975128174 1.1740200519561768 39.12894171697445 40.0 1.0 no 1079 chrIII_138462 3354 essential YCR012W 716 + TTTCACCTTCAAGAAGGTTT F|240|L silent|TTC>TTT|F|240 T|241|S T|241|I PGK1 3-PhosphoGlycerate Kinase 416.0 0 1 0 0 -0.3378778165097427 P00560 0.03516185283660889 0.009549942798912523 0.0012409277260303495 2.4828200340271 1.564460039138794 0.2699199914932251 44.440193222864416 35.0 1.0 no 1080 chrIII_138557r 3357 essential YCR012W 814 - GACTTCGACACCCTTGGCCT V|278|L V|278|I E|277|Q E|277|K PGK1 3-PhosphoGlycerate Kinase 416.0 0 1 0 0 1.193761988479625 P00560 0.586300790309906 1.0 0.24758616089820865 1.0 -0.1053600013256073 -0.06589999794960022 -0.5317999720573425 -1.0607199668884275 59.24934613083554 60.0 1.0 no 1081 chrIII_192125r 3364 essential YCR035C 871 + TTGCATTTGCTTCAAATTAT A|292|G A|292|V RRP43 Ribosomal RNA Processing 394.0 0 0 0 0 0.9201215165943722 P25359 1.0 0.21859386563301086 1.7473000288009644 0.9976199865341188 1.225000023841858 0.6186000108718872 39.73298600413312 25.0 0.0 no 1082 chrIII_192150 3365 essential YCR035C 849 - TTCTTTGCGTTTATCATTAA K|289|N silent|AAG>AAA|K|289 RRP43 Ribosomal RNA Processing 394.0 0 0 0 0 0.020220875074711403 P25359 0.18030335009098053 0.5634999871253967 40.62311355956257 25.0 0.0 no 1083 chrIII_192239 3366 essential YCR035C 760 - TCTTATAGTCATTCTTAAAT R|260|T R|260|K RRP43 Ribosomal RNA Processing 394.0 0 0 0 0 0.4972636019693256 P25359 0.012579490430653095 0.28231582045555115 0.3018600046634674 -0.11141999810934068 -0.18140000104904172 -0.09860000014305116 0.28496000170707697 0.07400000095367433 35.42082068156924 20.0 0.0 no 1084 chrIII_192471r 3368 essential YCR035C 525 + GTTCGTAGTGCGAATGAAGA R|177|G R|177|C RRP43 Ribosomal RNA Processing 394.0 0 0 0 0 -0.9074214299540188 P25359 0.029694292694330212 0.004118075594305992 2.9209001064300537 1.2642600536346436 2.487704038619995 0.7519753575325012 44.3014455526216 45.0 0.0 no 1085 chrIII_192491 3369 essential YCR035C 508 - AACACCAGCTTTTACCTTCA V|176|L V|176|I G|175|A G|175|D RRP43 Ribosomal RNA Processing 394.0 0 0 0 0 0.4098497161202417 P25359 0.4032573103904724 0.7010021209716797 0.061313342303037636 0.019076768308877945 -0.11615999788045885 -0.5894799828529358 4.42356014251709 10.895000457763672 -0.3283999860286713 -0.6380000114440918 2.878312110900879 2.0270490646362305 -0.4896489977836609 0.6002449989318848 49.396687558791825 40.0 0.0 no 1086 chrIII_192530r 3370 essential YCR035C 466 + ACGATTCCATATTGCACTCT H|156|Q silent|CAC>CAT|H|156 S|158|C S|158|F RRP43 Ribosomal RNA Processing 394.0 0 0 0 0 0.9988985274997686 P25359 0.06028831005096436 0.19077414274215695 0.5687867403030396 0.13048000633716586 0.6628599762916565 -2.6722400188446045 1.5125579833984375 0.8268799781799316 -0.6146968007087708 48.1655369976745 40.0 0.0 no 1087 chrIII_192603 3371 essential YCR035C 396 - CCTCTTTCAACTTCCACCAC R|138|T R|138|K G|139|R G|139|S RRP43 Ribosomal RNA Processing 394.0 0 1 0 0 0.2524317794375992 P25359 0.06022631004452705 0.1304587572813034 0.0 0.0 3.135740041732788 2.568959951400757 3.701280117034912 3.8268399238586426 3.48014497756958 2.338675022125244 10.737170219421387 6.3510499000549325 53.51116900581736 50.0 0.0 no 1088 chrIII_192695 3374 essential YCR035C 304 - ATCATCCAAATCTTTAATCG D|108|H D|108|N D|107|H D|107|N RRP43 Ribosomal RNA Processing 394.0 0 0 0 0 0.5582038709524978 P25359 0.2006593495607376 0.5353894233703613 0.3095695376396179 0.5524290204048157 0.2786000072956085 0.09920000284910202 -0.6528000235557556 -0.094200000166893 38.51186713576823 30.0 0.0 no 1089 chrIII_192700r 3375 essential YCR035C 296 + TAGCGCCGCGATTAAAGATT S|100|R silent|AGC>AGT|S|100 A|101|G A|101|V RRP43 Ribosomal RNA Processing 394.0 0 0 0 0 0.7214593867392801 P25359 0.5393829941749573 0.3769277930259705 0.2889547049999237 -0.046599999070167535 1.3458000421524048 46.36592260054936 45.0 0.0 no 1090 chrIII_192876 3378 essential YCR035C 123 - TCTTCATATTTTCTTAGACA E|48|Q E|48|K E|47|Q E|47|K RRP43 Ribosomal RNA Processing 394.0 0 0 0 0 0.4905946476439218 P25359 0.0 0.0 0.2026935964822769 0.12216558307409285 0.6198400259017944 0.7620000243186951 -0.14560000598430636 0.11326000094413755 1.0342600345611572 1.1893700361251829 -0.1045600026845932 -0.020059999078512192 40.033724727721456 25.0 0.0 no 1091 chrIII_192906r 3379 essential YCR035C 90 + TTACAAAGACACTTATCCCT Q|32|E Q|32|* RRP43 Ribosomal RNA Processing 394.0 0 0 0 0 0.14365754299477113 P25359 0.34687530994415283 1.8613799810409544 43.21562955430858 35.0 0.0 no 1092 chrIII_207303 3385 high_effect YCR044C 628 - TATCTTGGGGTACAGGAACA K|215|N silent|AAG>AAA|K|215 0 0 0 0 0.8931924060309608 P25625 0.4119856357574463 46.59122290340719 45.0 0.0 no 1093 chrIII_207373r 3387 high_effect YCR044C 555 + AAGCTAGATTACTTTTTCGC L|187|V silent|CTA>TTA|L|187 0 0 0 0 0.8072212508110881 P25625 0.0 42.814457277758656 35.0 0.0 no 1094 chrIII_207458r 3389 high_effect YCR044C 470 + GAACTACCTTTACGTTACTG N|158|K silent|AAC>AAT|N|158 Y|159|* silent|TAC>TAT|Y|159 0 0 0 0 0.4937790695781799 P25625 0.7785866856575012 42.94459323968806 40.0 0.0 no 1095 chrIII_207521r 3394 high_effect YCR044C 407 + TTCTAGAATCATACGCGAAG S|137|C S|137|F 0 0 0 0 -0.7116652906900256 P25625 0.17781248688697815 0.7020239233970642 39.884447317159534 40.0 0.0 no 1096 chrIII_207556r 3395 high_effect YCR044C 372 + AACTTTATTCCACATTATAA N|125|K silent|AAC>AAT|N|125 0 0 0 0 -0.4109301228868107 P25625 0.0 36.10236434666615 20.0 0.0 no 1097 chrIII_207626 3397 high_effect YCR044C 305 - TCAAAAATGGCCATTTCCCA L|108|F silent|TTG>TTA|L|108 0 0 0 0 1.0185782100167022 P25625 0.09825615584850313 46.84739169513364 40.0 0.0 no 1098 chrIII_207731r 3401 high_effect YCR044C 197 + GTACTCTAAGTTATTGTTCT Y|67|* silent|TAC>TAT|Y|67 S|68|C S|68|F 0 0 0 0 -1.0577901978514146 P25625 0.04989946633577347 0.05553913116455078 42.07366715063523 30.0 0.0 no 1099 chrIII_207736 3402 high_effect YCR044C 195 - AACAATAACTTAGAGTACAA L|71|F silent|TTG>TTA|L|71 0 0 0 0 -0.2501996786725704 P25625 0.0 32.18242602716822 25.0 0.0 no 1100 chrIII_207774 3403 high_effect YCR044C 157 - CTCAATATCATGAAACATGT E|59|Q E|59|K 0 0 0 0 0.7940559663754755 P25625 0.6668530702590942 0.9241374731063844 36.38448673444873 30.0 0.0 no 1101 chrIII_207871 3404 high_effect YCR044C 60 - AACTCATCTAAATTATCTCC E|26|D silent|GAG>GAA|E|26 E|26|Q E|26|K 0 0 0 0 0.7922809469323648 P25625 0.0622909925878048 0.035999458283185966 0.19240978360176086 38.887444619098524 30.0 0.0 no 1102 chrIII_210911 3406 high_effect YCR047C 615 - TTCACCTGCTCCTCCCCCTG silent|GTG>GTC|V|211 silent|GTG>GTA|V|211 V|211|L V|211|M BUD23 BUD site selection 275.0 0 0 0 0 -0.24779750587750984 P25627 0.9539830088615416 0.9587630033493042 0.31431588530540466 0.10527860373258592 67.31281243027485 65.0 0.0 no 1103 chrIII_210915 3407 high_effect YCR047C 611 - CCTGCTCCTCCCCCTGCGGT Q|210|H silent|CAG>CAA|Q|210 E|209|D silent|GAG>GAA|E|209 BUD23 BUD site selection 275.0 0 0 0 0 -1.564634868940596 P25627 0.9570760130882264 0.94931298494339 0.11607072502374648 0.6286253929138184 73.08595926304979 75.0 0.0 no 1104 chrIII_210966 3416 high_effect YCR047C 560 - TCTTATTCTTTTTAGACTCT K|193|N silent|AAG>AAA|K|193 BUD23 BUD site selection 275.0 0 0 0 0 0.10183830558366436 P25627 0.9355990290641784 0.010294822975993156 1.6737200021743774 41.32449613746542 25.0 0.0 no 1105 chrIII_211006 3418 high_effect YCR047C 520 - GCCACTGAACCCTGCCACCT G|180|R G|180|S G|180|A G|180|D BUD23 BUD site selection 275.0 0 0 0 0 0.05849490377760407 P25627 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.001787663553841412 0.012319226749241352 0.1545504331588745 0.0022218727972358465 8.166474342346191 7.268280029296875 5.0756001472473145 10.4679536819458 63.046366028341474 65.0 0.0 no 1106 chrIII_211023r 3422 high_effect YCR047C 500 + CGACATACTGCAGTCTGCCA D|168|E silent|GAC>GAT|D|168 BUD23 BUD site selection 275.0 0 0 0 0 1.117170020826972 P25627 0.9532920122146606 0.007977404631674291 -0.014340000227093697 54.12328975988361 55.00000000000001 0.0 no 1107 chrIII_211046 3424 high_effect YCR047C 480 - TCCACCTGGTCGTCGTTTTT silent|GTG>GTC|V|166 silent|GTG>GTA|V|166 D|167|H D|167|N BUD23 BUD site selection 275.0 0 0 0 0 0.32739593473968703 P25627 0.9486550092697144 0.956179976463318 0.13004229962825775 0.2643618881702423 -0.11206000298261642 -0.05496000126004219 56.95745770967022 50.0 0.0 no 1108 chrIII_211047 3425 high_effect YCR047C 479 - CCACCTGGTCGTCGTTTTTC V|166|L V|166|M silent|GTG>GTC|V|166 silent|GTG>GTA|V|166 BUD23 BUD site selection 275.0 0 0 0 0 -0.12495832808605654 P25627 0.9539830088615416 0.9587630033493042 0.6528114676475525 0.16607224941253662 -1.2477799654006958 -1.440019965171814 56.95745770967022 55.00000000000001 0.0 no 1109 chrIII_211268r 3440 high_effect YCR047C 255 + GGTCTTAGTAGAGAGCTGGA L|87|V L|87|F BUD23 BUD site selection 275.0 0 0 0 0 0.5084519328777536 P25627 0.9512209892272948 0.9587849974632264 0.5877071022987366 0.14559614658355713 0.5647799968719482 -0.4217399954795837 51.09914043157249 50.0 0.0 no 1110 chrIII_211376r 3447 high_effect YCR047C 147 + TTCATTCTGGATATCGGGTG F|50|L silent|TTC>TTT|F|50 L|52|V silent|CTG>TTG|L|52 BUD23 BUD site selection 275.0 0 0 0 0 -0.23717185466974425 P25627 0.9387490153312684 0.9512209892272948 0.9787901639938354 0.009592661634087564 0.3443399965763092 3.274980068206787 47.48382461825082 45.0 0.0 no 1111 chrIII_211431 3451 high_effect YCR047C 95 - CCCTCAGCGTCATCTTCGCC R|38|T R|38|K R|38|S silent|AGG>AGA|R|38 BUD23 BUD site selection 275.0 0 0 0 0 -0.7448326728423413 P25627 0.932735025882721 0.955805003643036 0.9087679982185364 0.0 0.0 0.0 2.082319974899292 1.139559984207153 2.850680112838745 63.12507352859189 65.0 0.0 no 1112 chrIII_211431r 3452 high_effect YCR047C 92 + CCAGGCGAAGATGACGCTGA Q|32|E Q|32|* A|33|G A|33|V BUD23 BUD site selection 275.0 0 0 0 0 -0.7902738449492773 P25627 0.9590039849281312 0.9484469890594482 0.9504740238189696 0.0 0.3286861479282379 0.5084381699562073 -0.2096399962902069 1.4136600494384766 -0.7276399731636047 51.513374838552636 60.0 0.0 no 1113 chrIII_211432r 3453 high_effect YCR047C 91 + TCCAGGCGAAGATGACGCTG Q|32|E Q|32|* I|31|M silent|ATC>ATT|I|31 BUD23 BUD site selection 275.0 0 0 0 0 -3.9541981750672837 P25627 0.9590039849281312 0.9598389863967896 0.0 0.0025498529430478807 -0.2096399962902069 0.13291999697685242 51.42613725581948 60.0 0.0 yes 1114 chrIII_215191r 3464 essential YCR052W 200 - GCATCTCTTTATTGGGGGGA M|73|I M|73|I E|72|D silent|GAG>GAA|E|72 RSC6 Remodel the Structure of Chromatin 483.0 0 0 0 0 -4.2393118963194265 P25632 0.970246970653534 0.970246970653534 0.9761919975280762 0.023309929296374318 0.023309929296374318 0.2520157396793365 53.68217513735141 50.0 1.0 yes 1115 chrIII_215195r 3465 essential YCR052W 204 - CTCAGCATCTCTTTATTGGG silent|CTG>CTC|L|74 silent|CTG>CTA|L|74 M|73|I M|73|I RSC6 Remodel the Structure of Chromatin 483.0 0 0 0 0 -0.5714152320270215 P25632 0.970246970653534 0.970246970653534 0.023309929296374318 0.023309929296374318 49.29838944394419 45.0 1.0 no 1116 chrIII_215197r 3466 essential YCR052W 206 - TCCTCAGCATCTCTTTATTG R|75|T R|75|K R|75|S silent|AGG>AGA|R|75 RSC6 Remodel the Structure of Chromatin 483.0 0 0 0 0 0.1997446522831265 P25632 0.9046339988708496 0.9230039715766908 0.8873720169067383 0.0 0.0 0.0 49.34576844004346 40.0 1.0 no 1117 chrIII_215196r 3467 essential YCR052W 205 - CCTCAGCATCTCTTTATTGG silent|CTG>CTC|L|74 silent|CTG>CTA|L|74 R|75|T R|75|K RSC6 Remodel the Structure of Chromatin 483.0 0 0 0 0 0.846248708034255 P25632 0.9046339988708496 0.9230039715766908 0.0 0.0 50.73518842445077 45.0 1.0 no 1118 chrIII_215199r 3468 essential YCR052W 208 - AATCCTCAGCATCTCTTTAT R|75|S silent|AGG>AGA|R|75 R|75|T R|75|K RSC6 Remodel the Structure of Chromatin 483.0 0 0 0 0 -0.4035525591360389 P25632 0.8873720169067383 0.9046339988708496 0.9230039715766908 0.0 0.0 0.0 47.35710628862779 35.0 1.0 no 1119 chrIII_215268r 3472 essential YCR052W 277 - AGTCTTGCCTGAGTCCGCTG K|98|N silent|AAG>AAA|K|98 RSC6 Remodel the Structure of Chromatin 483.0 0 0 0 0 -2.0181041518599976 P25632 0.9010649919509888 0.4433133602142334 60.04430438683301 60.0 1.0 yes 1120 chrIII_215348r 3477 essential YCR052W 357 - CCTTCCAAAAACTCACTAAA G|126|R G|126|S E|125|Q E|125|K RSC6 Remodel the Structure of Chromatin 483.0 0 0 0 0 0.6005323682142036 P25632 0.904865026473999 0.9219319820404052 0.9315000176429749 0.9194509983062744 0.0597788579761982 0.5683668255805969 1.0 0.053136367350816734 39.24081980405544 35.0 1.0 no 1121 chrIII_215399r 3479 essential YCR052W 408 - CTCTTCTTGCCCATGCCCAG K|142|N silent|AAG>AAA|K|142 K|141|N silent|AAG>AAA|K|141 RSC6 Remodel the Structure of Chromatin 483.0 0 0 0 0 -2.8707783863930887 P25632 0.9018030166625975 0.9054740071296692 0.3767949044704437 0.4922924041748047 62.244687235579356 60.0 1.0 yes 1122 chrIII_215541r 3485 essential YCR052W 550 - TGCGTCTACAATTTCCTCCC A|190|P A|190|T D|189|H D|189|N RSC6 Remodel the Structure of Chromatin 483.0 0 0 0 0 -0.9162555660455786 P25632 0.9846779704093932 0.97638601064682 0.974511981010437 0.9857460260391236 0.1204848289489746 0.33766546845436096 0.01076751109212637 0.037103474140167236 54.6471195351229 50.0 1.0 no 1123 chrIII_215646 3487 essential YCR052W 652 + GCAGTATAACCATCCAGTTG C|218|W silent|TGC>TGT|C|218 RSC6 Remodel the Structure of Chromatin 483.0 0 0 0 0 0.3750497310123342 P25632 0.8880190253257751 0.0011841686209663749 48.7566914338272 45.0 1.0 no 1124 chrIII_215728 3493 essential YCR052W 734 + AACGGGCTCCGTTAATGACG T|246|R T|246|M silent|GGC>GGG|G|247 silent|GGC>GGT|G|247 RSC6 Remodel the Structure of Chromatin 483.0 0 0 0 0 0.183862323897696 P25632 0.9375799894332886 0.9519019722938538 1.0 0.0445970818400383 48.706278951882545 55.00000000000001 1.0 no 1125 chrIII_215832r 3496 essential YCR052W 841 - ATTCTCGTTACTGCTGTCTT E|286|D silent|GAG>GAA|E|286 E|286|Q E|286|K RSC6 Remodel the Structure of Chromatin 483.0 0 0 0 0 -0.010018535344060995 P25632 0.9535670280456544 0.961425006389618 0.9493749737739564 0.6186084151268005 0.5825812816619873 0.9220722317695618 50.48238433408728 40.0 1.0 no 1126 chrIII_215903 3497 essential YCR052W 909 + CCAAAGGATAAGCCCGAATT P|304|R P|304|L RSC6 Remodel the Structure of Chromatin 483.0 0 1 0 0 0.3104065437239548 P25632 0.9589099884033204 0.9670220017433168 0.12203863263130188 0.05002029612660408 45.36478306607768 45.0 1.0 no 1127 chrIII_215916r 3499 essential YCR052W 925 - TAGCTTCACTTCACCCAATT K|314|N silent|AAG>AAA|K|314 silent|GTG>GTC|V|313 silent|GTG>GTA|V|313 RSC6 Remodel the Structure of Chromatin 483.0 0 0 0 0 0.3686100581038983 P25632 0.9648680090904236 0.26845782995224 49.723135865010136 40.0 1.0 no 1128 chrIII_215941 3501 essential YCR052W 947 + TTCACTCTTACAAAAGGTAT S|317|* S|317|L L|318|V L|318|F RSC6 Remodel the Structure of Chromatin 483.0 0 0 0 0 0.581341757502999 P25632 0.9589700102806092 0.9141610264778136 0.9229249954223632 0.23239721357822415 0.5109272003173828 0.6833969354629517 38.23957529402463 30.0 1.0 no 1129 chrIII_218972 3508 essential YCR054C 1076 - ACAAGTCAGAAATTATGTCC L|365|F silent|TTG>TTA|L|365 D|364|H D|364|N CTR86 Copper TRansport protein 563.0 0 0 0 0 0.3686944144296017 P25355 0.9587849974632264 0.9486550092697144 0.956179976463318 0.15537989139556885 0.1308939903974533 0.5369436740875244 39.66367407086825 35.0 0.0 no 1130 chrIII_219077r 3510 essential YCR054C 968 + TCTGCAACGTCTTGCATGCA L|324|V silent|CTG>TTG|L|324 Q|325|E Q|325|* CTR86 Copper TRansport protein 563.0 0 0 0 0 -1.2051052274479708 P25355 0.9512209892272948 0.9590039849281312 0.11155056208372116 1.0 52.5780311962431 50.0 0.0 no 1131 chrIII_219223r 3513 essential YCR054C 822 + TCTTTTGGTAAATACCTCAA S|275|C S|275|F CTR86 Copper TRansport protein 563.0 0 0 0 0 0.3894229349459991 P25355 0.945252001285553 0.9294660091400146 0.0 0.0 40.57643881727137 30.0 0.0 no 1132 chrIII_219238r 3515 essential YCR054C 807 + AGTCTTACAACTGCTTCTTT L|271|V L|271|F CTR86 Copper TRansport protein 563.0 0 0 0 0 1.0279295800128023 P25355 0.9512209892272948 0.9587849974632264 1.0 0.07446562498807907 45.96451862469411 35.0 0.0 no 1133 chrIII_219411 3518 essential YCR054C 637 - AACACAATAATAGTCTTTCT V|219|L V|219|I C|218|S C|218|Y CTR86 Copper TRansport protein 563.0 0 0 0 0 0.2887553210886456 P25355 0.9539830088615416 0.9574310183525084 0.9421560168266296 0.9290120005607604 35.87092175555216 25.0 0.0 no 1134 chrIII_219538 3521 essential YCR054C 510 - TCTTCCAATTTGATCCCATA D|177|H D|177|N E|176|Q E|176|K CTR86 Copper TRansport protein 563.0 0 0 0 0 0.19340644135274224 P25355 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.17869292199611664 0.3250555396080017 0.5538706779479979 0.7817098498344421 47.95506509370017 35.0 0.0 no 1135 chrIII_219712r 3524 essential YCR054C 333 + CTACAAAACCTCGTAATTCG Q|113|E Q|113|* CTR86 Copper TRansport protein 563.0 0 0 0 0 0.6997967075462395 P25355 0.9590039849281312 0.2579404711723328 39.6477699763206 40.0 0.0 no 1136 chrIII_219846 3529 essential YCR054C 202 - TGGCAACAGCATTGCTTCCA L|73|F silent|TTG>TTA|L|73 silent|CTG>CTC|L|72 silent|CTG>CTA|L|72 CTR86 Copper TRansport protein 563.0 0 0 0 0 -1.0642893353225351 P25355 0.9587849974632264 0.695400595664978 53.84471313567508 50.0 0.0 no 1137 chrIII_221161r 3537 essential YCR057C 2045 + TTCGGTGCAATTCTCCCCAA S|683|W S|683|L PWP2 Periodic tryptophan (W) Protein 923.0 0 0 0 0 -0.8472683934338578 P25635 0.9288619756698608 0.9298099875450134 0.015831762924790382 0.09729688614606856 54.725082722592795 50.0 0.0 no 1138 chrIII_221354 3542 essential YCR057C 1855 - ACCATTCAAAGCCATGTTTC G|625|R G|625|S G|625|A G|625|D PWP2 Periodic tryptophan (W) Protein 923.0 0 0 0 0 0.2269525381236391 P25635 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.004213889129459858 0.08293565362691879 0.7279698252677917 0.004986136686056852 47.17014081785914 40.0 0.0 no 1139 chrIII_221365r 3544 essential YCR057C 1841 + ATTCATTGTGTCCAGAAACA F|615|L silent|TTC>TTT|F|615 PWP2 Periodic tryptophan (W) Protein 923.0 0 0 0 0 -1.445233684083108 P25635 0.9387490153312684 0.008097486570477486 43.20362144753466 35.0 0.0 no 1140 chrIII_221463r 3546 essential YCR057C 1743 + ACAATACATTACAGTTTTGA T|582|R T|582|I H|584|D H|584|Y PWP2 Periodic tryptophan (W) Protein 923.0 0 0 0 0 0.5031609559249194 P25635 0.9476869702339172 0.9472420215606691 0.9473130106925964 0.9489949941635132 0.003847170621156693 0.0043981801718473434 0.15628169476985931 0.08318823575973511 36.72564480238208 25.0 0.0 no 1141 chrIII_221581r 3548 essential YCR057C 1625 + CAACATAGAAGATGCCAAGC N|543|K silent|AAC>AAT|N|543 PWP2 Periodic tryptophan (W) Protein 923.0 0 0 0 0 0.6050572969843349 P25635 0.9439849853515624 0.014337880536913872 42.385732096153156 45.0 0.0 no 1142 chrIII_221689 3549 essential YCR057C 1520 - CTTCTATAGGTTCTACTTGT E|513|Q E|513|K PWP2 Periodic tryptophan (W) Protein 923.0 0 0 0 0 -0.6774172969675133 P25635 0.956179976463318 0.9475290179252625 0.8417872190475464 0.8411985635757446 45.64603933287635 35.0 0.0 no 1143 chrIII_221855r 3551 essential YCR057C 1351 + ACAATTTTGACATTCATGTT D|451|E silent|GAC>GAT|D|451 PWP2 Periodic tryptophan (W) Protein 923.0 0 0 0 0 1.2216703109147276 P25635 0.9532920122146606 0.1033373400568962 38.52266310782449 25.0 0.0 no 1144 chrIII_221889 3553 essential YCR057C 1320 - GCACAAACCACTTCACCTGA C|446|S C|446|Y A|447|P A|447|T PWP2 Periodic tryptophan (W) Protein 923.0 0 0 0 0 -0.4816093472562151 P25635 0.9421560168266296 0.9290120005607604 0.9573720097541808 0.9523990154266356 0.3495079576969147 0.004279017448425293 0.0064007071778178215 0.004394541960209608 50.23123229245977 50.0 0.0 no 1145 chrIII_222116 3558 essential YCR057C 1093 - AACTTTGATTTTCCCATCTT V|371|L V|371|I PWP2 Periodic tryptophan (W) Protein 923.0 0 0 0 0 1.1821303160827452 P25635 0.9539830088615416 0.9574310183525084 0.5643933415412903 0.3321693241596222 45.50701792026189 30.0 0.0 no 1146 chrIII_222202r 3563 essential YCR057C 1004 + ATCGTATATCTTGAAGCAGC S|336|W S|336|L PWP2 Periodic tryptophan (W) Protein 923.0 0 0 0 0 -0.027939803067202614 P25635 0.9288619756698608 0.9298099875450134 0.0006049232906661928 0.002516442677006125 44.32645697230794 40.0 0.0 no 1147 chrIII_222233r 3566 essential YCR057C 973 + GCCAATTACTAGTTTACGAA Q|326|E Q|326|* silent|GGC>GGG|G|325 silent|GGC>GGT|G|325 PWP2 Periodic tryptophan (W) Protein 923.0 0 0 0 0 -2.1276358279312904 P25635 0.9590039849281312 0.0073424847796559325 42.00215981364715 35.0 0.0 yes 1148 chrIII_222383r 3577 essential YCR057C 823 + TAGCTGTCGGATTTACTAGT A|276|G A|276|V PWP2 Periodic tryptophan (W) Protein 923.0 0 0 0 0 0.3606971729836896 P25635 0.9484469890594482 0.9504740238189696 0.0012602974893525245 1.0 46.93840748906508 40.0 0.0 no 1149 chrIII_222396r 3580 essential YCR057C 810 + GCAACAAGGCTTTTAGCTGT A|271|G A|271|V T|272|R T|272|I PWP2 Periodic tryptophan (W) Protein 923.0 0 0 0 0 -0.837983634496754 P25635 0.9484469890594482 0.9504740238189696 0.9476869702339172 0.9472420215606691 0.3958438038825989 0.25949934124946594 0.02842017635703087 0.059907902032136924 49.189120339497144 45.0 0.0 no 1150 chrIII_222410r 3582 essential YCR057C 796 + TCACCTTCCATCCAGCAACA T|267|S T|267|I silent|GTC>GTG|V|266 silent|GTC>GTT|V|266 PWP2 Periodic tryptophan (W) Protein 923.0 0 0 0 0 0.8200309843441479 P25635 0.9491789937019348 0.9472420215606691 0.2194058895111084 0.1587238609790802 55.10008236735695 50.0 0.0 no 1151 chrIII_222430 3583 essential YCR057C 779 - TGACACACTTTACTTTGGCT V|266|L V|266|I C|265|S C|265|Y PWP2 Periodic tryptophan (W) Protein 923.0 0 0 0 0 0.8569261728824886 P25635 0.9539830088615416 0.9574310183525084 0.9421560168266296 0.9290120005607604 0.015284957364201547 0.01884930580854416 0.5803477168083191 0.007718676701188086 46.870975514895065 40.0 0.0 no 1152 chrIII_222574r 3586 essential YCR057C 632 + AGACGGTGCTGTCTTTGTCT D|212|E silent|GAC>GAT|D|212 PWP2 Periodic tryptophan (W) Protein 923.0 0 0 0 0 0.0028936684290593877 P25635 0.9532920122146606 0.04625514894723892 54.49542966576935 50.0 0.0 no 1153 chrIII_222686 3592 essential YCR057C 523 - GTTCTTTTCCTCTGAATCTA K|180|N silent|AAG>AAA|K|180 PWP2 Periodic tryptophan (W) Protein 923.0 0 0 0 0 -0.6886674389718581 P25635 0.9355990290641784 0.4670555591583252 47.15108879838152 35.0 0.0 no 1154 chrIII_222808r 3596 essential YCR057C 398 + TGCTCCCTTCGTCCGCCATA A|134|G A|134|V P|135|A P|135|S PWP2 Periodic tryptophan (W) Protein 923.0 0 0 0 0 1.0798872833927584 P25635 0.9484469890594482 0.9504740238189696 0.9562489986419678 0.9498909711837769 0.32752132415771484 0.33248522877693176 0.3897202610969544 0.08046308904886246 63.32682740118771 60.0 0.0 no 1155 chrIII_222809r 3597 essential YCR057C 397 + TTGCTCCCTTCGTCCGCCAT A|134|G A|134|V P|135|A P|135|S PWP2 Periodic tryptophan (W) Protein 923.0 0 0 0 0 0.9256145627039656 P25635 0.9484469890594482 0.9504740238189696 0.9562489986419678 0.9498909711837769 0.32752132415771484 0.33248522877693176 0.3897202610969544 0.08046308904886246 64.13836003316948 60.0 0.0 no 1156 chrIII_222834 3598 essential YCR057C 375 - TGTCTGTCTTTATTAACATC R|131|T R|131|K PWP2 Periodic tryptophan (W) Protein 923.0 0 0 0 0 0.6035685327187188 P25635 0.932735025882721 0.955805003643036 0.08886497467756271 0.6102773547172546 40.46012839559535 30.0 0.0 no 1157 chrIII_222866 3599 essential YCR057C 343 - AATCTGTAAAAACCTGCCTG Q|120|H silent|CAG>CAA|Q|120 PWP2 Periodic tryptophan (W) Protein 923.0 0 0 0 0 0.21148254828493995 P25635 0.9570760130882264 0.4728087186813354 42.080128687762105 40.0 0.0 no 1158 chrIII_223028 3604 essential YCR057C 181 - GCCTTGTTTGTTCAGATCAA G|67|R G|67|S G|67|A G|67|D PWP2 Periodic tryptophan (W) Protein 923.0 0 0 0 0 0.28631285121218714 P25635 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.002094422001391649 0.08914355933666229 0.08965892344713211 0.002734477398917079 49.17458911616552 40.0 0.0 no 1159 chrIII_223128r 3609 essential YCR057C 78 + AAGCAACTACTCTCACCGGT Q|28|E Q|28|* L|29|V silent|CTA>TTA|L|29 PWP2 Periodic tryptophan (W) Protein 923.0 0 0 0 0 1.0822866512809064 P25635 0.9590039849281312 0.9512209892272948 0.04971027001738548 1.0 50.510389935977905 50.0 0.0 no 1160 chrIII_223152r 3612 essential YCR057C 54 + AACATCACCTTTTCCGATGA N|19|K silent|AAC>AAT|N|19 I|20|M silent|ATC>ATT|I|20 PWP2 Periodic tryptophan (W) Protein 923.0 0 0 0 0 -0.36733817886838704 P25635 0.9439849853515624 0.9598389863967896 0.005010573659092188 0.02443920262157917 46.95015851875553 40.0 0.0 no 1161 chrIII_241495r 3619 essential YCR072C 835 + ATTCAGTGTCTTGTGTCAAA S|280|* S|280|L RSA4 RiboSome Assembly 515.0 0 0 0 0 -0.3482499882967177 P25382 0.9298099875450134 0.006927269976586104 0.14499999582767487 44.20573817386645 35.0 0.0 no 1162 chrIII_241616 3621 essential YCR072C 717 - CCCGGCTTCACAAGATGTAT silent|CCG>CCC|P|245 silent|CCG>CCA|P|245 G|246|R G|246|S RSA4 RiboSome Assembly 515.0 0 0 0 1 0.08803686604827847 P25382 0.941340982913971 0.951104998588562 0.18830837309360504 0.9108794927597046 3.2335999011993413 3.7416000366210938 51.628740348576116 50.0 0.0 no 1163 chrIII_241617r 3623 essential YCR072C 713 + ACCTATACATCTTGTGAAGC P|239|R P|239|L P|239|A P|239|S RSA4 RiboSome Assembly 515.0 0 0 0 0 -0.7549285743315717 P25382 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 9.76580047607422 6.1276001930236825 2.920399904251098 5.03980016708374 44.96543856392265 40.0 0.0 no 1164 chrIII_241746 3629 essential YCR072C 587 - TAGCAATTACTTCTCCATCG A|202|P A|202|T RSA4 RiboSome Assembly 515.0 0 0 0 0 -2.509793127207611 P25382 0.9573720097541808 0.9523990154266356 0.008104704320430756 0.010856357403099535 3.596400022506714 -0.23240000009536746 0.7351999878883362 2.5971999168396 45.54756877012869 40.0 0.0 yes 1165 chrIII_241747 3632 essential YCR072C 586 - AGCAATTACTTCTCCATCGG A|202|P A|202|T RSA4 RiboSome Assembly 515.0 0 0 0 0 -3.134671776706188 P25382 0.9573720097541808 0.9523990154266356 0.008104704320430756 0.010856357403099535 3.596400022506714 -0.23240000009536746 0.7351999878883362 2.5971999168396 48.448335476167536 45.0 0.0 yes 1166 chrIII_241799 3635 essential YCR072C 534 - TGACCCTTTAGAGTATGCAT G|184|A G|184|D G|184|R G|184|S RSA4 RiboSome Assembly 515.0 0 0 0 0 -0.441229688725784 P25382 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.0 0.0 0.0 0.0 3.830600023269653 4.893199920654297 5.945799827575684 4.61899995803833 48.65182533323253 40.0 0.0 no 1167 chrIII_241803r 3636 essential YCR072C 527 + AACGCCAATGCATACTCTAA T|177|R T|177|M P|178|A P|178|S RSA4 RiboSome Assembly 515.0 0 0 0 0 -2.007943501072885 P25382 0.9476869702339172 0.9502379894256592 0.9562489986419678 0.9498909711837769 0.004463428165763617 0.11243464797735214 0.022441519424319267 0.011222747154533865 -0.7111999988555908 -0.3273999989032745 1.1837999820709229 2.059999942779541 44.11075773812939 40.0 0.0 no 1168 chrIII_241802r 3637 essential YCR072C 528 + ACGCCAATGCATACTCTAAA P|178|A P|178|S T|177|R T|177|M RSA4 RiboSome Assembly 515.0 0 0 0 0 -0.15050032968447366 P25382 0.9562489986419678 0.9498909711837769 0.9476869702339172 0.9502379894256592 0.022441519424319267 0.011222747154533865 0.004463428165763617 0.11243464797735214 1.1837999820709229 2.059999942779541 -0.7111999988555908 -0.3273999989032745 44.11075773812939 40.0 0.0 no 1169 chrIII_241849 3639 essential YCR072C 484 - TGCAGTATTATCACCTGCAC A|168|P A|168|T RSA4 RiboSome Assembly 515.0 0 0 0 0 0.3614811536342401 P25382 0.9573720097541808 0.9523990154266356 0.035264171659946435 0.10988884419202803 1.3544000387191772 1.4515999555587769 1.937600016593933 4.320000171661377 49.89888901334905 45.0 0.0 no 1170 chrIII_241959r 3646 essential YCR072C 371 + AGCAGTTTTCAAAGTCAAGC A|125|G A|125|V RSA4 RiboSome Assembly 515.0 0 0 0 0 1.0276633543705658 P25382 0.9484469890594482 0.9504740238189696 0.01746784150600433 0.005393057130277157 1.0329999923706057 0.4336000084877014 43.91510279775218 40.0 0.0 no 1171 chrIII_242312 3652 essential YCR072C 21 - TTCTTTTGTTTCTTAGAAGG K|13|N silent|AAG>AAA|K|13 RSA4 RiboSome Assembly 515.0 0 0 0 0 0.4703841384312676 P25382 0.9355990290641784 0.15822473168373108 40.539139853028985 30.0 0.0 no 1172 chrIII_280798r 3661 essential YCR093W 684 - TTCGTTGCGTCTAAAACCAT silent|ACG>ACC|T|234 silent|ACG>ACA|T|234 CDC39 Cell Division Cycle 2108.0 0 0 0 0 0.4577289841978432 P25655 45.11915357374505 40.0 1.0 no 1173 chrIII_281159r 3666 essential YCR093W 1045 - TTCTAAATTCAATGATGCAA E|355|Q E|355|K CDC39 Cell Division Cycle 2108.0 0 0 0 0 0.863952941949808 P25655 0.17685097455978396 0.31955718994140625 -0.2994999885559082 -0.8014000058174133 35.03385072111257 25.0 1.0 no 1174 chrIII_281309 3668 essential YCR093W 1192 + TCGTTTTATTGATAGAAAAC F|398|L silent|TTC>TTT|F|398 CDC39 Cell Division Cycle 2108.0 0 0 0 0 0.9916106887775092 P25655 0.5768283605575562 1.3309199810028076 32.924283064619885 25.0 1.0 no 1175 chrIII_281569r 3672 essential YCR093W 1455 - CAACCAATTTGTCTTGCGCA G|491|A G|491|D G|491|R G|491|S CDC39 Cell Division Cycle 2108.0 0 0 0 0 0.5958570435181384 P25655 0.04890715330839157 0.0341867059469223 0.023894503712654117 0.037856776267290115 3.6241400241851807 4.3870601654052725 3.618880033493042 4.00059986114502 48.741168853425215 45.0 1.0 no 1176 chrIII_281824 3679 essential YCR093W 1707 + TTTCCTAGATTGATCAATTT P|571|A P|571|S P|571|R P|571|L CDC39 Cell Division Cycle 2108.0 0 0 0 0 0.9741901372771524 P25655 0.0 0.0 0.0 0.0 2.441380023956299 3.921880006790161 3.046260118484497 3.0594599246978764 39.818146662324246 25.0 1.0 no 1177 chrIII_281873r 3681 essential YCR093W 1759 - AATCCCTGCGATGTCACCAT silent|GGG>GGC|G|592 silent|GGG>GGA|G|592 G|592|A G|592|E CDC39 Cell Division Cycle 2108.0 0 0 0 0 -0.12834639634288822 P25655 0.3283565044403076 0.07103121280670166 3.5006999969482417 3.4423201084136963 54.00656214467705 50.0 1.0 no 1178 chrIII_282039r 3683 essential YCR093W 1925 - TCGATTCTGCTATAACGGCA silent|TCG>TCC|S|648 silent|TCG>TCA|S|648 E|647|Q E|647|K CDC39 Cell Division Cycle 2108.0 0 0 0 0 0.4118949147546978 P25655 0.0 0.0 0.4539799988269806 0.31064000725746155 47.41960430265283 45.0 1.0 no 1179 chrIII_282063 3685 essential YCR093W 1946 + ATTCTTCCAAGATTATCCAT F|650|L silent|TTC>TTT|F|650 F|651|L silent|TTC>TTT|F|651 CDC39 Cell Division Cycle 2108.0 0 0 0 0 0.1885967841805735 P25655 0.0 0.0 0.3582000136375427 0.26875999569892883 0.38429999351501465 44.26999366094049 30.0 1.0 no 1180 chrIII_282206r 3691 essential YCR093W 2092 - TACAGCAAACTTAAACATCT V|704|L V|704|I A|703|P A|703|T CDC39 Cell Division Cycle 2108.0 0 0 0 0 0.2438695416133147 P25655 0.033854272216558456 0.161074697971344 0.02000043354928493 0.020751357078552246 -1.2085200548171997 -0.4444600045681 9.11818027496338 4.323379993438722 36.497601249461816 30.0 1.0 no 1181 chrIII_282227 3692 essential YCR093W 2110 + TACAAGCTATTTATGCATTT Q|705|E Q|705|* A|706|G A|706|V CDC39 Cell Division Cycle 2108.0 0 0 0 0 0.6741864232879442 P25655 0.0 0.03877807408571243 0.0129733607172966 0.5172200202941895 1.8653000593185425 0.008659999817609787 39.32253415958093 25.0 1.0 no 1182 chrIII_282285r 3694 essential YCR093W 2171 - AAGCCGGAACATCTCTCAAG A|730|P A|730|T silent|CCG>CCC|P|729 silent|CCG>CCA|P|729 CDC39 Cell Division Cycle 2108.0 0 0 0 0 0.010470339453561128 P25655 0.06896526366472244 0.07301856577396393 -1.152999997138977 2.009999990463257 46.640449983657284 50.0 1.0 no 1183 chrIII_282460r 3700 essential YCR093W 2346 - ACTTTTTCTACGACATCTTT V|789|L V|789|I CDC39 Cell Division Cycle 2108.0 0 0 0 0 1.1032026635538026 P25655 0.07645346224308014 1.0 0.21442000567913053 0.2701199948787689 42.7207037234744 30.0 1.0 no 1184 chrIII_282578 3701 essential YCR093W 2461 + CCACATATTTAGTTACGCAA T|822|R T|822|I silent|TCC>TCG|S|821 silent|TCC>TCT|S|821 CDC39 Cell Division Cycle 2108.0 0 0 0 0 -0.3847606101330552 P25655 0.4699128270149231 0.1902199238538742 -0.6271600127220154 -0.9047600030899048 43.04836959672747 35.0 1.0 no 1185 chrIII_282578r 3702 essential YCR093W 2464 - CCTTTGCGTAACTAAATATG R|828|T R|828|K silent|ACG>ACC|T|826 silent|ACG>ACA|T|826 CDC39 Cell Division Cycle 2108.0 0 0 0 0 -0.2876524404751797 P25655 0.0 0.0 5.413980007171631 2.438040018081665 2.9711599349975586 0.8055800199508667 39.369696110987896 35.0 1.0 no 1186 chrIII_282579 3703 essential YCR093W 2462 + CACATATTTAGTTACGCAAA T|822|R T|822|I CDC39 Cell Division Cycle 2108.0 0 0 0 0 -0.15978477050600864 P25655 0.4699128270149231 0.1902199238538742 -0.6271600127220154 -0.9047600030899048 38.01998695878369 30.0 1.0 no 1187 chrIII_282752 3707 essential YCR093W 2635 + ACCTAAAGAATTTGGCTTCA L|880|V silent|CTA>TTA|L|880 H|879|Q silent|CAC>CAT|H|879 CDC39 Cell Division Cycle 2108.0 0 0 0 0 -0.12660974355061747 P25655 0.020058684051036838 0.18285387754440308 2.5121400356292725 -0.5875999927520752 42.52838117505064 35.0 1.0 no 1188 chrIII_282812 3710 essential YCR093W 2695 + AACACAAGAATATCGCATTC H|900|D H|900|Y H|900|Q silent|CAC>CAT|H|900 CDC39 Cell Division Cycle 2108.0 0 0 0 0 -0.6122570690413329 P25655 0.022019267082214355 0.4335246384143829 0.1629602164030075 -0.31797999143600464 -1.787700057029724 -0.16774000227451324 -0.03173999860882759 -0.3481000065803528 0.12943999469280246 37.845172530855216 35.0 1.0 no 1189 chrIII_283116 3716 essential YCR093W 2999 + TGCTTTGGGATCAATCACTC A|1001|G A|1001|V CDC39 Cell Division Cycle 2108.0 0 0 0 0 -0.006059878951740289 P25655 0.3856397271156311 0.28300604224205017 47.61697700957642 45.0 1.0 no 1190 chrIII_283142 3717 essential YCR093W 3025 + AACAACAAACAGAGCAACAA Q|1010|E Q|1010|* Q|1011|E Q|1011|* CDC39 Cell Division Cycle 2108.0 0 0 0 0 -0.8964471694849088 P25655 0.2437686622142792 0.5826289653778076 34.91975886455566 35.0 1.0 no 1191 chrIII_283327 3721 essential YCR093W 3210 + AATCCTTTTAACAACTTACT P|1072|A P|1072|S P|1072|R P|1072|L CDC39 Cell Division Cycle 2108.0 0 0 0 0 0.7449447699512681 P25655 1.0 0.4941785335540772 0.3306042551994324 0.7990450263023376 37.90463230915697 25.0 1.0 no 1192 chrIII_283364 3723 essential YCR093W 3247 + TAACCCACCCTGACTTGAAG T|1084|S T|1084|I silent|ACC>ACG|T|1084 silent|ACC>ACT|T|1084 CDC39 Cell Division Cycle 2108.0 0 0 0 0 -0.5039793000848309 P25655 0.0 0.0 49.49084764331417 50.0 1.0 no 1193 chrIII_283582 3727 essential YCR093W 3465 + TCAATTGAACCATTGAAAGA S|1156|* S|1156|L CDC39 Cell Division Cycle 2108.0 0 0 0 0 0.6212664666240438 P25655 0.13495028018951416 36.125785242437026 30.0 1.0 no 1194 chrIII_283591r 3728 essential YCR093W 3477 - GAACGTATGCCTTCTTTCAA R|1165|P R|1165|H CDC39 Cell Division Cycle 2108.0 0 0 0 0 0.20674778130507648 P25655 0.030080843716859818 0.17056110501289368 46.16535971238221 40.0 1.0 no 1195 chrIII_283647 3730 essential YCR093W 3530 + TCTTTCTTCTTCACCTGCAG L|1178|V L|1178|F S|1179|C S|1179|F CDC39 Cell Division Cycle 2108.0 0 0 0 0 -0.3717785426274915 P25655 0.9473064541816713 0.07747843861579895 0.047459736466407776 0.05017094686627388 52.73011769682279 45.0 1.0 no 1196 chrIII_283779 3733 essential YCR093W 3662 + TGCTATTCGTCGTTATCACA A|1222|G A|1222|V CDC39 Cell Division Cycle 2108.0 0 0 0 0 1.2386199731664151 P25655 0.038286156952381134 0.02028893493115902 47.665460723040844 40.0 1.0 no 1197 chrIII_283843r 3735 essential YCR093W 3729 - TCTGGTAAAGACAGTGAATA E|1250|Q E|1250|K CDC39 Cell Division Cycle 2108.0 0 0 0 0 -0.1428427427784721 P25655 0.049344033002853394 0.03881518170237541 0.05654000118374825 0.26739999651908875 38.14032060980975 35.0 1.0 no 1198 chrIII_283983 3739 essential YCR093W 3866 + TCCACCGATGACTCAAAATG P|1290|R P|1290|L P|1290|A P|1290|S CDC39 Cell Division Cycle 2108.0 0 0 0 0 0.04602724127181407 P25655 0.42205810546875 0.3055203258991241 1.0 0.7292752265930176 43.439058971782124 45.0 1.0 no 1199 chrIII_283984r 3741 essential YCR093W 3870 - CCCACATTTTGAGTCATCGG silent|GTG>GTC|V|1296 silent|GTG>GTA|V|1296 G|1297|R G|1297|S CDC39 Cell Division Cycle 2108.0 0 0 0 0 -0.9432618930896486 P25655 0.5240529775619507 0.8514063358306885 51.26437931558007 50.0 1.0 no 1200 chrIII_284175 3747 essential YCR093W 4058 + TGCTGCAGTTCAATCAGATT A|1354|G A|1354|V A|1355|G A|1355|V CDC39 Cell Division Cycle 2108.0 0 0 0 0 -0.0425231651400068 P25655 0.38158953189849854 0.29646036028862 0.4177034795284271 0.2920680046081543 47.20928568396272 40.0 1.0 no 1201 chrIII_284208 3748 essential YCR093W 4091 + ACGTGTTCTCGTTCACCTCA R|1365|G R|1365|C CDC39 Cell Division Cycle 2108.0 0 0 0 0 -0.248983126753227 P25655 0.4279764890670776 0.06922505050897597 54.9940063237525 50.0 1.0 no 1202 chrIII_284472r 3751 essential YCR093W 4358 - CAACGTCTTTTCTAGCAACG V|1459|L V|1459|I D|1458|H D|1458|N CDC39 Cell Division Cycle 2108.0 0 0 0 0 0.6962629599345949 P25655 0.0 0.0 0.031312987208366394 0.13052262365818024 44.25466452651386 45.0 1.0 no 1203 chrIII_284471r 3752 essential YCR093W 4357 - AACGTCTTTTCTAGCAACGA V|1459|L V|1459|I D|1458|H D|1458|N CDC39 Cell Division Cycle 2108.0 0 0 0 0 0.1618701006582591 P25655 0.0 0.0 0.031312987208366394 0.13052262365818024 44.15312313967479 40.0 1.0 no 1204 chrIV_33612r 3757 essential YDL235C 284 + CTTCCCCAACAAGACCGAAT F|96|L silent|TTC>TTT|F|96 P|97|A P|97|S YPD1 tYrosine Phosphatase Dependent 167.0 0 0 0 0 -0.13707419270310184 Q07688 0.8588870167732239 0.8583599925041199 0.8547409772872925 1.8917399644851685 2.526619911193848 3.0756320953369136 1.9842679500579836 49.504238616652344 50.0 0.0 no 1205 chrIV_33768r 3760 essential YDL235C 128 + TGCTCAAATGCAACGACAGC A|44|G A|44|V Q|45|E Q|45|* YPD1 tYrosine Phosphatase Dependent 167.0 0 0 0 0 1.0474927336606903 Q07688 0.821956992149353 0.8172299861907959 0.8218129873275757 0.28190383315086365 0.21159017086029053 1.0 0.7948799729347229 1.3566800355911257 0.3559800088405609 0.9611700177192688 0.15884000062942505 45.645933330956154 50.0 0.0 no 1206 chrIV_33883 3761 essential YDL235C 16 - GGTCCAATTGATGATTTCTG W|11|C W|11|* W|11|S W|11|* YPD1 tYrosine Phosphatase Dependent 167.0 0 0 0 0 -0.7669389416613022 Q07688 0.7585269808769226 0.745248019695282 0.030314888805150982 0.06025102734565735 3.1370880603790283 3.243220090866089 2.272252082824707 2.3374040126800537 44.74096709225415 40.0 0.0 no 1207 chrIV_46743 3763 exception YDL227C 1269 - ACGGGTTCCCTTTTTATAAT V|430|L V|430|I 0 0 0 0 0.17959108836837118 P09932 0.3327305316925049 0.35486963391304016 -0.3941999971866608 -0.5419999957084656 47.27037553679844 35.0 0.0 no 1208 chrIV_46843 3768 exception YDL227C 1169 - AGTCGTATGTAAATTGACAT D|396|H D|396|N 0 0 0 0 0.6087311908007359 P09932 0.12235760688781737 0.4911854267120361 38.220949429177324 30.0 0.0 no 1209 chrIV_46984 3773 exception YDL227C 1028 - TTGCTATTTTATAAGATTCA A|349|P A|349|T 0 1 0 0 0.4864401810586566 P09932 0.05059622973203659 0.7009169459342957 4.60860013961792 1.8614000082015991 36.21835471650672 20.0 0.0 no 1210 chrIV_47030 3774 exception YDL227C 982 - CCCATCTGAGTCGATCAAGC G|334|R G|334|R G|334|A G|334|E 0 0 0 0 -1.216702060714368 P09932 0.005366514902561903 0.005366514902561903 0.1742001324892044 0.0072688618674874314 52.58122099843053 55.00000000000001 0.0 no 1211 chrIV_47079 3778 exception YDL227C 933 - TGCTCGCCGTACATAAATTC E|317|D silent|GAG>GAA|E|317 E|317|Q E|317|K 0 0 0 0 0.02672578147948296 P09932 1.0 0.04436616972088814 0.035027243196964264 46.825426785580596 45.0 0.0 no 1212 chrIV_47080 3779 exception YDL227C 932 - GCTCGCCGTACATAAATTCA E|317|Q E|317|K E|317|D silent|GAG>GAA|E|317 0 0 0 0 -0.03922309134251378 P09932 0.04436616972088814 0.035027243196964264 1.0 48.029726565374354 45.0 0.0 no 1213 chrIV_47395r 3787 exception YDL227C 614 + AACTCCTGCTGTAAAAAGTA T|206|S T|206|I P|207|A P|207|S 0 0 0 0 -0.45844671922570795 P09932 0.6339804530143738 0.17729856073856354 0.3600715696811676 0.4048686027526856 40.26080015082283 35.0 0.0 no 1214 chrIV_47454 3788 exception YDL227C 558 - ACACCATTTCCTGCGAGTAC G|192|A G|192|D V|193|L V|193|I 0 0 0 0 0.8800638214679108 P09932 0.10344649851322174 0.5244749188423157 0.6807425022125244 0.4117497801780701 -1.0238000154495241 -0.9416000247001648 52.15987864285694 50.0 0.0 no 1215 chrIV_47524r 3790 exception YDL227C 485 + TGACATTGAAGTTAGAGATT D|163|E silent|GAC>GAT|D|163 0 0 0 0 0.4203653606648569 P09932 1.0 37.08142863594003 30.0 0.0 no 1216 chrIV_47579 3791 exception YDL227C 433 - TTCTTCTATGAAGCGTTTTG E|151|Q E|151|K E|150|Q E|150|K 0 0 0 0 0.7102867781891169 P09932 0.6412484645843506 0.9112799167633056 0.3739748299121857 0.7991151213645935 -0.8203999996185303 3.5929999351501465 42.68922721683504 35.0 0.0 no 1217 chrIV_47604 3792 exception YDL227C 408 - AACTCACCTTCAACTGTCAT E|142|D silent|GAG>GAA|E|142 E|142|Q E|142|K 0 0 0 0 0.38131577194899535 P09932 0.4582368433475494 0.6129558682441711 0.930827021598816 46.47910249377594 40.0 0.0 no 1218 chrIV_47605 3793 exception YDL227C 407 - ACTCACCTTCAACTGTCATT E|142|Q E|142|K E|142|D silent|GAG>GAA|E|142 0 0 0 0 0.3435467877766011 P09932 0.6129558682441711 0.930827021598816 0.4582368433475494 48.36188492776824 40.0 0.0 no 1219 chrIV_47620 3795 exception YDL227C 392 - TCATTGGGAATGTCTTATGA M|137|I M|137|I 0 0 0 0 -0.03474100228813942 P09932 0.4164358973503113 0.4164358973503113 1.0920000076293943 1.0920000076293943 42.43563144387275 35.0 0.0 no 1220 chrIV_47696 3797 exception YDL227C 316 - TCTCCATCTCACTTTATATT W|111|C W|111|* R|112|T R|112|K 0 0 0 0 0.05457213287105206 P09932 0.07960019260644913 0.39743533730506897 0.3565844893455505 -5.551400184631348 -1.80840003490448 -1.1591999530792236 45.23722739622343 30.0 0.0 no 1221 chrIV_47937r 3804 exception YDL227C 72 + TCTTACGTTATGTGCGCAGA S|25|C S|25|F Y|26|* silent|TAC>TAT|Y|26 0 0 0 0 -0.158883273627643 P09932 0.044905386865139015 0.04601546376943588 49.26320939821711 45.0 0.0 no 1222 chrIV_63102 3813 essential YDL220C 1897 - CGGCTCACATTCGCGCACAA E|638|D silent|GAG>GAA|E|638 E|638|Q E|638|K CDC13 Cell Division Cycle 924.0 0 0 0 0 -0.417231825155337 P32797 0.6023300290107727 0.5757830739021301 0.9227786064147948 -0.1379999965429306 -0.5134000182151794 -0.819599986076355 53.88244555302367 60.0 0.0 no 1223 chrIV_63478r 3823 essential YDL220C 1518 + ACCATCGAATTCTGTCAGTT silent|ACC>ACG|T|507 silent|ACC>ACT|T|507 T|507|S T|507|I CDC13 Cell Division Cycle 924.0 0 0 0 0 -0.91331549098129 P32797 0.3970852792263031 0.592765212059021 -0.13220000267028809 1.9825999736785889 47.47438717414241 40.0 0.0 no 1224 chrIV_63616 3830 essential YDL220C 1383 - AAACTCCATACTGCCATACC S|467|T S|467|N W|466|C W|466|* CDC13 Cell Division Cycle 924.0 0 0 0 0 -1.2024692101875625 P32797 1.0 0.32301658391952515 0.005609703715890646 -0.5536400079727173 -0.3632600009441376 4.038939952850342 48.52303993828969 45.0 0.0 no 1225 chrIV_63617 3832 essential YDL220C 1382 - AACTCCATACTGCCATACCT S|467|T S|467|N W|466|C W|466|* CDC13 Cell Division Cycle 924.0 0 0 0 0 -4.2248755205737965 P32797 1.0 0.32301658391952515 0.005609703715890646 -0.5536400079727173 -0.3632600009441376 4.038939952850342 51.78654858625902 45.0 0.0 yes 1226 chrIV_63676 3837 essential YDL220C 1323 - ACTTCGACGGAAATTCGATC V|448|L V|448|I E|447|Q E|447|K CDC13 Cell Division Cycle 924.0 0 0 0 0 -0.9255490820811124 P32797 0.6233571171760559 0.9485002160072328 0.45716738700866705 0.5288015007972717 0.9823600053787231 -0.4923999905586242 -0.06939999759197235 -0.4321799874305725 42.32990071782945 45.0 0.0 no 1227 chrIV_63760 3839 essential YDL220C 1239 - TCACAGATTCGCTCTCTCGT C|419|S C|419|Y E|420|Q E|420|K CDC13 Cell Division Cycle 924.0 0 0 0 0 0.2100965504350697 P32797 0.4086374342441559 1.0 0.5851885080337524 0.9773143529891968 0.046819999814033515 0.8758000135421753 -0.2332600057125092 0.14560000598430636 0.4096600115299225 1.5423799753189087 53.16482890356672 50.0 0.0 no 1228 chrIV_64051 3852 essential YDL220C 948 - TCATCATCGTGCCAATTATT D|323|H D|323|N D|322|H D|322|N CDC13 Cell Division Cycle 924.0 0 1 0 0 0.8801484829502759 P32797 0.017547840252518654 0.05117659270763397 45.76294080355444 35.0 0.0 no 1229 chrIV_64134r 3856 essential YDL220C 862 + CCTCAACTACCTCCTCTACC S|289|* S|289|L silent|TCC>TCG|S|288 silent|TCC>TCT|S|288 CDC13 Cell Division Cycle 924.0 0 0 0 0 -2.9452738841236936 P32797 56.353372342518355 55.00000000000001 0.0 yes 1230 chrIV_64135r 3858 essential YDL220C 861 + TCCTCAACTACCTCCTCTAC silent|TCC>TCG|S|288 silent|TCC>TCT|S|288 S|288|C S|288|F CDC13 Cell Division Cycle 924.0 0 0 0 0 0.2434378248239505 P32797 53.89972994054028 50.0 0.0 no 1231 chrIV_64251 3862 essential YDL220C 748 - CTGCGAGTTGAATTCGTTTT silent|TCG>TCC|S|255 silent|TCG>TCA|S|255 CDC13 Cell Division Cycle 924.0 0 0 0 0 -0.18132019742485744 P32797 45.412549752769955 40.0 0.0 no 1232 chrIV_64555 3867 essential YDL220C 444 - ATCACACTTACCAAATCCAA silent|GTG>GTC|V|154 silent|GTG>GTA|V|154 V|154|L V|154|M CDC13 Cell Division Cycle 924.0 0 0 0 1 -0.9250900200228144 P32797 0.2444334626197815 0.07274942100048065 0.8937280178070068 0.12080200016498566 42.608414045478746 35.0 0.0 no 1233 chrIV_64609r 3870 essential YDL220C 387 + GCTTTATATGTATCAAAACA A|130|G A|130|V CDC13 Cell Division Cycle 924.0 0 0 0 0 0.044581698183377434 P32797 0.5745499730110168 0.2482542246580124 1.8240499496459959 -0.9472579956054688 35.855241428879765 25.0 0.0 no 1234 chrIV_64667 3871 essential YDL220C 332 - TATCTCTCAGTATTACTGTT D|117|H D|117|N R|116|T R|116|K CDC13 Cell Division Cycle 924.0 0 0 0 0 0.3817760596222813 P32797 0.04879380390048027 0.7288841605186462 0.3712281882762909 0.6097822189331055 1.1764620542526243 0.4040859937667847 0.3123019933700561 -0.06636399775743483 43.20477015786157 30.0 0.0 no 1235 chrIV_64668 3872 essential YDL220C 331 - ATCTCTCAGTATTACTGTTG D|117|H D|117|N R|116|T R|116|K CDC13 Cell Division Cycle 924.0 0 0 0 0 -0.6064417350328823 P32797 0.04879380390048027 0.7288841605186462 0.3712281882762909 0.6097822189331055 1.1764620542526243 0.4040859937667847 0.3123019933700561 -0.06636399775743483 43.82375871877667 35.0 0.0 no 1236 chrIV_64696r 3873 essential YDL220C 300 + CCAGATTTAGATTCTGACTC P|101|R P|101|L CDC13 Cell Division Cycle 924.0 0 0 0 0 0.5549319745959285 P32797 0.08603941649198532 0.047082241624593735 0.5426719784736633 0.20044399797916407 44.395137738427756 40.0 0.0 no 1237 chrIV_64914 3879 essential YDL220C 85 - CACGGGAACTATTGCTTTGC V|35|L V|35|M CDC13 Cell Division Cycle 924.0 0 0 0 0 0.06155631777495079 P32797 0.3580617904663086 0.029827432706952095 0.7582060098648071 1.243988037109375 48.14138582974789 50.0 0.0 no 1238 chrIV_68218r 3884 essential YDL217C 366 + TACTCTAGTGCTAAGAATTT Y|123|* silent|TAC>TAT|Y|123 S|124|C S|124|F TIM22 Translocase of the Inner Mitochondrial membrane 207.0 0 0 0 0 0.006700570425102359 Q12328 0.945252001285553 0.9294660091400146 0.0063195256516337395 0.007286402862519027 39.283856502298704 30.0 0.0 no 1239 chrIV_68251r 3885 essential YDL217C 333 + AAACTTCAATTTACCGATAT L|113|V L|113|F Q|114|E Q|114|* TIM22 Translocase of the Inner Mitochondrial membrane 207.0 0 0 0 0 0.6994555354733373 Q12328 0.9512209892272948 0.9587849974632264 0.9590039849281312 0.5556177496910095 0.7041071653366089 0.3163183927536011 36.50200181009046 25.0 0.0 no 1240 chrIV_68353 3890 essential YDL217C 234 - GCAGTTGCTGCTGTATTTGC A|85|P A|85|T TIM22 Translocase of the Inner Mitochondrial membrane 207.0 0 0 0 0 0.005433655188025258 Q12328 0.9573720097541808 0.9523990154266356 54.96166390853455 50.0 0.0 no 1241 chrIV_68463 3897 essential YDL217C 124 - CACAACTGATTTTCCAGGAC V|48|L V|48|M V|47|L V|47|I TIM22 Translocase of the Inner Mitochondrial membrane 207.0 0 0 0 0 1.5111946255340118 Q12328 0.9539830088615416 0.9587630033493042 0.9539830088615416 0.9574310183525084 0.5317794680595398 1.0 0.2117595076560974 0.7380045652389526 45.264661285211446 45.0 0.0 no 1242 chrIV_68476r 3899 essential YDL217C 108 + AACTTCATGACTTCCTGTCC N|37|K silent|AAC>AAT|N|37 F|38|L silent|TTC>TTT|F|38 TIM22 Translocase of the Inner Mitochondrial membrane 207.0 0 0 0 0 0.3349463448368524 Q12328 0.9439849853515624 0.9387490153312684 0.9017678499221802 0.7930233478546143 50.35869985987205 45.0 0.0 no 1243 chrIV_68534r 3903 essential YDL217C 50 + ACCTTATAATGAACTAACTC P|18|R P|18|L P|18|A P|18|S TIM22 Translocase of the Inner Mitochondrial membrane 207.0 0 0 0 0 -1.208974294234658 Q12328 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0152595192193985 0.016897441819310192 0.17042416334152222 0.3832722306251526 36.565420485636935 30.0 0.0 no 1244 chrIV_68533 3904 essential YDL217C 54 - TCCGGAGTTAGTTCATTATA silent|CCG>CCC|P|24 silent|CCG>CCA|P|24 E|25|Q E|25|K TIM22 Translocase of the Inner Mitochondrial membrane 207.0 0 0 0 0 0.17811148601810806 Q12328 0.956179976463318 0.9475290179252625 0.05893995612859726 0.19974945485591888 45.51253167116829 35.0 0.0 no 1245 chrIV_78473 3905 essential YDL212W 47 + ATCGGCCACAACGTTCCTAA S|17|W S|17|L A|18|G A|18|V SHR3 Super high Histidine Resistant 210.0 0 0 0 0 0.5280713489261819 Q02774 0.9288619756698608 0.9298099875450134 0.9484469890594482 0.9504740238189696 0.18770597875118256 0.6994088292121887 0.06343787163496017 0.04013520479202271 51.19560463683068 50.0 1.0 no 1246 chrIV_78478r 3907 essential YDL212W 55 - AACACCCATTAGGAACGTTG V|25|L V|25|I G|24|A G|24|D SHR3 Super high Histidine Resistant 210.0 0 0 0 0 -0.2336269872662487 Q02774 0.9539830088615416 0.9574310183525084 0.9499930143356324 0.9446240067481996 0.245383694767952 0.2743683457374573 0.0 0.0 45.15871860631761 45.0 1.0 no 1247 chrIV_78686r 3913 essential YDL212W 263 - ACTCAAACATCTGCAGTTCA E|94|Q E|94|K E|94|D silent|GAG>GAA|E|94 SHR3 Super high Histidine Resistant 210.0 0 0 0 0 -0.06481721662543348 Q02774 0.956179976463318 0.9475290179252625 0.94931298494339 0.0 0.0 0.0 45.42045362494713 40.0 1.0 no 1248 chrIV_78687r 3914 essential YDL212W 264 - TACTCAAACATCTGCAGTTC E|94|D silent|GAG>GAA|E|94 E|94|Q E|94|K SHR3 Super high Histidine Resistant 210.0 0 0 0 0 -0.06298362362128719 Q02774 0.94931298494339 0.956179976463318 0.9475290179252625 0.0 0.0 0.0 43.51030029937693 40.0 1.0 no 1249 chrIV_78775 3915 essential YDL212W 349 + ACTGTTCTGTGAGCCATAAT D|117|E silent|GAC>GAT|D|117 S|119|C S|119|F SHR3 Super high Histidine Resistant 210.0 0 0 0 0 -0.8351969169467375 Q02774 0.9532920122146606 0.945252001285553 0.9294660091400146 1.0 1.0 0.017520265653729442 47.662644742821435 40.0 1.0 no 1250 chrIV_86585 3922 essential YDL209C 622 - ATCATCCCATTCTTTATCGC D|214|H D|214|N D|213|H D|213|N CWC2 Complexed With Cef1p 339.0 0 0 0 0 -0.6783868748945452 Q12046 -0.20715999603271484 -0.5602200031280518 0.17124000191688538 -0.10261999815702437 50.399606477355576 40.0 0.0 no 1251 chrIV_86725r 3927 essential YDL209C 479 + TCGATTTGTATTTTCTCGAT R|161|G R|161|* CWC2 Complexed With Cef1p 339.0 0 0 0 0 -0.4473561693723293 Q12046 0.26139652729034424 1.529420018196106 42.128709659310005 30.0 0.0 no 1252 chrIV_86748 3928 essential YDL209C 459 - ATTCTGCTTTCTATCTGAGC R|159|T R|159|K S|158|T S|158|N CWC2 Complexed With Cef1p 339.0 0 0 0 0 0.4389454138465436 Q12046 0.5492951273918152 0.5958907008171082 0.40527498722076416 0.442997932434082 3.79010009765625 1.6763800382614136 0.4731999933719635 0.07568000257015227 48.61604183029374 40.0 0.0 no 1253 chrIV_86925 3936 essential YDL209C 282 - TTACCTATATCTTCTTCGTC G|100|A G|100|D G|100|R G|100|S CWC2 Complexed With Cef1p 339.0 0 0 0 0 0.06655262927627711 Q12046 -0.9871000051498412 -0.3399200141429901 -1.0039600133895874 -0.7519000172615051 45.850023675265454 35.0 0.0 no 1254 chrIV_87037r 3938 essential YDL209C 167 + ACTTCATTCTGGGAAGACTA L|57|V L|57|F H|58|D H|58|Y CWC2 Complexed With Cef1p 339.0 0 1 0 0 0.8538472906195183 Q12046 0.02378968335688114 0.008750647306442259 1.0 0.005809419322758913 0.6967399716377258 0.5965399742126465 1.4821799993515017 1.4431400299072266 0.7274399995803833 0.6175000071525574 1.151419997215271 0.7277600169181824 44.57005929055504 40.0 0.0 no 1255 chrIV_87047r 3940 essential YDL209C 157 + TGCAGCCGCAACTTCATTCT Q|54|E Q|54|* P|55|A P|55|S CWC2 Complexed With Cef1p 339.0 0 0 0 0 -0.04839697898590351 Q12046 0.1265392303466797 0.2847767472267151 0.05271424725651741 0.26862001419067383 2.082319974899292 3.3409199714660645 54.050140103711946 50.0 0.0 no 1256 chrIV_87048r 3941 essential YDL209C 156 + TTGCAGCCGCAACTTCATTC Q|54|E Q|54|* P|55|A P|55|S CWC2 Complexed With Cef1p 339.0 0 0 0 0 -0.23067872226294064 Q12046 0.1265392303466797 0.2847767472267151 0.05271424725651741 0.26862001419067383 2.082319974899292 3.3409199714660645 52.55807090087745 50.0 0.0 no 1257 chrIV_87146 3943 essential YDL209C 61 - TCCAGTCTGCGCCGGTATAG G|27|R G|27|R G|27|A G|27|E CWC2 Complexed With Cef1p 339.0 0 0 0 0 -0.9641162948188756 Q12046 0.0 0.0 0.0 0.0 1.024500012397766 1.024500012397766 0.3955999910831451 0.5133000016212463 58.04731332459739 60.0 0.0 no 1258 chrIV_87558r 3948 essential YDL208W 100 - TCTGGCCTCATAGTTGTCTA R|40|T R|40|K A|39|P A|39|T NHP2 Non-Histone Protein 156.0 0 0 0 0 -0.15642090626978222 P32495 53.96570242393785 45.0 1.0 no 1259 chrIV_87616 3950 essential YDL208W 155 + CTCTAAGAAACTAAACAAGA S|53|C S|53|F NHP2 Non-Histone Protein 156.0 0 0 0 0 0.09559901288983326 P32495 31.64805448736263 30.0 1.0 no 1260 chrIV_87708r 3953 essential YDL208W 250 - ACCTTTTTCACCCTTTCTTA G|90|R G|90|S G|90|A G|90|D NHP2 Non-Histone Protein 156.0 0 0 0 0 -0.9904797114684872 P32495 51.75241659639454 35.0 1.0 no 1261 chrIV_88293r 3956 essential YDL207W 48 - GAACATGTTTCCTCAAATTC C|22|S C|22|Y GLE1 GLFG (glycine-leucine-phenylalanine-glycine) LEthal 538.0 0 0 0 0 0.535510178154895 Q12315 0.9421560168266296 0.9290120005607604 0.4114686846733093 1.0 40.9238193482924 35.0 1.0 no 1262 chrIV_88500r 3962 essential YDL207W 255 - ATCGATGACGCGGCTACAAT silent|TCG>TCC|S|91 silent|TCG>TCA|S|91 GLE1 GLFG (glycine-leucine-phenylalanine-glycine) LEthal 538.0 0 0 0 0 -0.7033389842359392 Q12315 47.58228926700775 50.0 1.0 no 1263 chrIV_88612r 3966 essential YDL207W 367 - TTCTTCTATTGCCTCGAGTA E|129|Q E|129|K E|128|Q E|128|K GLE1 GLFG (glycine-leucine-phenylalanine-glycine) LEthal 538.0 0 0 0 0 0.43644787889025183 Q12315 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.5663561224937439 0.9231908321380616 0.5933588743209839 0.8399372696876526 50.07921390290619 40.0 1.0 no 1264 chrIV_88611r 3967 essential YDL207W 366 - TCTTCTATTGCCTCGAGTAA E|129|Q E|129|K E|128|Q E|128|K GLE1 GLFG (glycine-leucine-phenylalanine-glycine) LEthal 538.0 0 0 0 0 0.7727902495894778 Q12315 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.5663561224937439 0.9231908321380616 0.5933588743209839 0.8399372696876526 48.104004967034136 40.0 1.0 no 1265 chrIV_93013 3983 essential YDL205C 713 - TCATCAAAGCACGCTCCGAA M|244|I M|244|I L|243|F silent|TTG>TTA|L|243 HEM3 HEMe biosynthesis 327.0 0 0 0 0 0.4456090064529269 P28789 0.9553959965705872 0.9553959965705872 0.9587849974632264 0.039616242051124566 0.039616242051124566 0.04892585799098015 48.263350014007074 50.0 0.0 no 1266 chrIV_93097 3985 essential YDL205C 629 - CCTTTCTAATTTCTATACCC K|216|N silent|AAG>AAA|K|216 R|215|T R|215|K HEM3 HEMe biosynthesis 327.0 0 0 0 0 -0.3260793113268601 P28789 0.9355990290641784 0.932735025882721 0.955805003643036 0.3135339915752411 0.00909368321299553 0.04669547826051712 46.452684816989795 35.0 0.0 no 1267 chrIV_93118 3989 essential YDL205C 608 - GGGCGCCTTGTCCAACTGCA A|209|P A|209|T G|208|A G|208|D HEM3 HEMe biosynthesis 327.0 0 0 0 0 -3.0897668573087325 P28789 0.9573720097541808 0.9523990154266356 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 5.347640037536621 0.770359992980957 62.06256492469424 65.0 0.0 yes 1268 chrIV_93185r 3990 essential YDL205C 538 + CTGCTGGGTTGATGCGTATG A|181|G A|181|V HEM3 HEMe biosynthesis 327.0 0 0 0 0 -3.1039446792533094 P28789 0.9484469890594482 0.9504740238189696 0.017793470993638042 0.005533038172870874 1.5195000171661377 -0.8012999892234802 52.15296483858504 55.00000000000001 0.0 yes 1269 chrIV_93201r 3994 essential YDL205C 522 + TGCATCATCTTGGCGTCTGC C|175|W silent|TGC>TGT|C|175 I|176|M silent|ATC>ATT|I|176 HEM3 HEMe biosynthesis 327.0 0 0 0 0 0.12719238459094845 P28789 0.9286419749259948 0.9598389863967896 0.0022261471021920447 0.2456424832344055 22.29283905029297 56.28034221467988 55.00000000000001 0.0 no 1270 chrIV_93211r 3995 essential YDL205C 512 + TCCGTACCAATGCATCATCT P|172|R P|172|L P|172|A P|172|S HEM3 HEMe biosynthesis 327.0 0 0 0 0 -0.15186891798080168 P28789 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.10871221870183943 0.097389854490757 0.23779135942459104 0.17120301723480225 51.11531979103819 45.0 0.0 no 1271 chrIV_93317 3999 essential YDL205C 409 - TAGCTGAGCAGATCTTCTCA Q|142|H silent|CAG>CAA|Q|142 HEM3 HEMe biosynthesis 327.0 0 0 0 0 -1.9074299391326872 P28789 0.9570760130882264 0.0 50.388855765375574 45.0 0.0 no 1272 chrIV_93323 4000 essential YDL205C 403 - AGCAGATCTTCTCACGGATG A|141|P A|141|T HEM3 HEMe biosynthesis 327.0 0 0 0 0 -5.587735859768066 P28789 0.9573720097541808 0.9523990154266356 0.008123250678181648 0.0066937278024852285 49.0759163055651 50.0 0.0 yes 1273 chrIV_93345 4001 essential YDL205C 381 - GTTCCCACAATCCCCCCGTC G|133|A G|133|E G|133|R G|133|R HEM3 HEMe biosynthesis 327.0 0 0 0 0 -2.103601772127912 P28789 0.9499930143356324 0.9438679814338684 0.941340982913971 0.941340982913971 0.0 0.0 0.0 0.0 65.20652678751145 65.0 0.0 yes 1274 chrIV_93376r 4008 essential YDL205C 347 + TTACTCTGCTTATAAGTCTC Y|117|* silent|TAC>TAT|Y|117 S|118|C S|118|F HEM3 HEMe biosynthesis 327.0 0 0 0 0 0.6853794524057533 P28789 0.945252001285553 0.9294660091400146 0.20252223312854767 0.706562340259552 43.37043555908854 35.0 0.0 no 1275 chrIV_93402 4011 essential YDL205C 324 - GGCATGACAAGACAATCTGT M|114|I M|114|I HEM3 HEMe biosynthesis 327.0 0 0 0 0 -0.5347803081472289 P28789 0.9553959965705872 0.9553959965705872 0.20011809468269348 0.20011809468269348 2.3382198810577397 2.3382198810577397 44.84442507679182 45.0 0.0 no 1276 chrIV_93447r 4014 essential YDL205C 276 + CTACCAGAGGGTTTCGAGCT P|94|A P|94|S P|94|R P|94|L HEM3 HEMe biosynthesis 327.0 0 0 0 0 -1.8758444991545216 P28789 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.015126789920032024 0.01003476232290268 0.012915839441120623 0.005009409040212631 54.42621714008385 55.00000000000001 0.0 no 1277 chrIV_93448r 4015 essential YDL205C 275 + ACTACCAGAGGGTTTCGAGC L|93|V silent|CTA>TTA|L|93 P|94|A P|94|S HEM3 HEMe biosynthesis 327.0 0 0 0 0 -1.2831846724077849 P28789 0.9512209892272948 0.9562489986419678 0.9498909711837769 0.009877131320536137 0.015126789920032024 0.01003476232290268 1.416200041770935 53.06091628109914 55.00000000000001 0.0 no 1278 chrIV_93459r 4017 essential YDL205C 264 + ATGCCCACTTTACTACCAGA P|90|A P|90|S P|90|R P|90|L HEM3 HEMe biosynthesis 327.0 0 1 0 0 -0.6461080732553783 P28789 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.0 0.0 0.0 0.0 52.437358454143585 45.0 0.0 no 1279 chrIV_93500 4018 essential YDL205C 226 - GATCAAGTCAAGCTTCTTTG L|81|F silent|TTG>TTA|L|81 HEM3 HEMe biosynthesis 327.0 0 1 0 0 0.6013338762362455 P28789 0.9587849974632264 0.1794874221086502 43.633772897389285 40.0 0.0 no 1280 chrIV_93511 4019 essential YDL205C 215 - GCTTCTTTGAGGGATCGTCA K|78|N silent|AAG>AAA|K|78 K|77|N silent|AAG>AAA|K|77 HEM3 HEMe biosynthesis 327.0 0 0 0 0 -1.6743626209382878 P28789 0.9355990290641784 0.9355990290641784 0.12770910561084747 0.14322254061698916 1.0901199579238892 0.05575999990105629 53.04226161613457 50.0 0.0 no 1281 chrIV_93570 4021 essential YDL205C 156 - TTACCGCCAAATGAGTACAA G|58|A G|58|D G|58|R G|58|S HEM3 HEMe biosynthesis 327.0 0 0 0 0 0.38336286301072375 P28789 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 1.0 0.024424441158771515 0.02255956083536148 0.16198740899562836 2.251499891281128 1.9402400255203247 2.020080089569092 2.346400022506714 43.78825869930171 40.0 0.0 no 1282 chrIV_93717 4028 essential YDL205C 9 - CCACCAATATGTAGAGTTTC G|9|A G|9|D G|10|R G|10|R HEM3 HEMe biosynthesis 327.0 0 0 0 0 -5.404069603697273 P28789 0.9499930143356324 0.9446240067481996 0.941340982913971 0.941340982913971 0.08559473603963852 0.0035785345826298 0.045296300202608115 0.045296300202608115 1.7126200199127195 10.820940017700195 45.23626118575186 40.0 0.0 yes 1283 chrIV_93717r 4029 essential YDL205C 6 + CCTGAAACTCTACATATTGG P|3|R P|3|L HEM3 HEMe biosynthesis 327.0 0 0 0 0 0.8401813656077823 P28789 0.9432820081710817 0.9430609941482544 0.6050977110862732 0.2547309398651123 41.575651196232904 40.0 0.0 no 1284 chrIV_106748r 4031 essential YDL196W 10 - AGACAATCTTTTCCTTGACT L|9|F silent|TTG>TTA|L|9 0 0 0 0 -0.8741700031674203 Q12187 0.9587849974632264 44.693503083739984 35.0 1.0 no 1285 chrIV_106925 4036 essential YDL196W 184 + TATCCCCTTCCATCCCCTTC S|63|C S|63|F silent|TCC>TCG|S|63 silent|TCC>TCT|S|63 0 0 0 0 -0.016287076897063532 Q12187 0.945252001285553 0.9294660091400146 64.21693602877349 55.00000000000001 1.0 no 1286 chrIV_107239r 4039 essential YDL195W 34 - ATCATGTGACCACGCAAACG D|18|H D|18|N SEC31 SECretory 1273.0 0 0 0 0 -1.69329896255 P38968 0.9486550092697144 0.956179976463318 0.1513512283563614 0.2494378238916397 6.164539813995361 1.7386000156402588 45.93721728809271 50.0 1.0 no 1287 chrIV_107476r 4045 essential YDL195W 271 - AGCGTTGTTTGCTTCATTGG A|97|P A|97|T SEC31 SECretory 1273.0 0 0 0 0 -0.32486082789267845 P38968 0.9573720097541808 0.9523990154266356 0.2414250671863556 0.5736496448516846 50.93808308979754 45.0 1.0 no 1288 chrIV_107533r 4047 essential YDL195W 328 - AAACTTTACCGTCTTCACAG K|115|N silent|AAG>AAA|K|115 SEC31 SECretory 1273.0 0 0 0 0 -2.81774059571051 P38968 0.9355990290641784 0.18157295882701874 43.68076048066672 40.0 1.0 yes 1289 chrIV_107640r 4050 essential YDL195W 435 - GTCAATGGAGTATAATTGGA L|151|F silent|TTG>TTA|L|151 SEC31 SECretory 1273.0 0 0 0 0 -1.5961249592458846 P38968 0.9587849974632264 0.33223846554756165 39.8923061084098 35.0 1.0 no 1290 chrIV_107725 4057 essential YDL195W 517 + CCCATGTTTTTGCATCTGCC H|174|D H|174|Y silent|GCC>GCG|A|173 silent|GCC>GCT|A|173 SEC31 SECretory 1273.0 0 0 0 0 0.548450564318115 P38968 0.9473130106925964 0.9489949941635132 0.0 0.0 56.98209213296508 50.0 1.0 no 1291 chrIV_107725r 4058 essential YDL195W 520 - CCCGGCAGATGCAAAAACAT G|180|R G|180|R G|180|A G|180|E SEC31 SECretory 1273.0 0 0 0 0 -0.872605704101247 P38968 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.041253142058849335 0.041253142058849335 0.6667299866676331 0.07138638943433763 46.97455057185277 50.0 1.0 no 1292 chrIV_107749 4059 essential YDL195W 541 + CGTCTAATTTCGCATCTATT S|182|C S|182|F SEC31 SECretory 1273.0 0 0 0 0 0.7677088390943365 P38968 0.945252001285553 0.9294660091400146 0.007851351983845234 0.004070817492902279 43.92032918087102 35.0 1.0 no 1293 chrIV_107750 4060 essential YDL195W 542 + GTCTAATTTCGCATCTATTT S|182|C S|182|F SEC31 SECretory 1273.0 0 0 0 0 -0.620610880252905 P38968 0.945252001285553 0.9294660091400146 0.007851351983845234 0.004070817492902279 42.89142322063873 30.0 1.0 no 1294 chrIV_107949 4064 essential YDL195W 741 + CCATTGCAGACTTTAAATCA P|248|R P|248|L Q|250|E Q|250|* SEC31 SECretory 1273.0 0 1 0 0 -0.5986400312405011 P38968 0.9432820081710817 0.9430609941482544 0.9590039849281312 0.0 0.0 0.08843773603439331 42.44873547295202 35.0 1.0 no 1295 chrIV_108015 4066 essential YDL195W 807 + GAACATCTATTATTGTCCAG H|271|D H|271|Y L|272|V silent|CTA>TTA|L|272 SEC31 SECretory 1273.0 0 0 0 0 0.052062699961618886 P38968 0.9473130106925964 0.9489949941635132 0.9512209892272948 0.8265311121940613 0.1199079006910324 0.06888000667095184 41.55471251951997 35.0 1.0 no 1296 chrIV_108095r 4071 essential YDL195W 890 - AACACCAGTTTCCACGAGCT C|303|S C|303|Y W|302|C W|302|* SEC31 SECretory 1273.0 0 0 0 0 -0.32931024670443343 P38968 0.9421560168266296 0.9290120005607604 0.8858469724655151 0.023494981229305267 0.006877181585878135 0.08566609025001526 52.39348316665104 50.0 1.0 no 1297 chrIV_108096r 4073 essential YDL195W 891 - AAACACCAGTTTCCACGAGC C|303|S C|303|Y W|302|C W|302|* SEC31 SECretory 1273.0 0 0 0 0 -0.3772085175270908 P38968 0.9421560168266296 0.9290120005607604 0.8858469724655151 0.023494981229305267 0.006877181585878135 0.08566609025001526 49.08376183471688 50.0 1.0 no 1298 chrIV_108280r 4075 essential YDL195W 1075 - CTTCTCTTTTGATTCCTCTC E|364|D silent|GAG>GAA|E|364 E|364|Q E|364|K SEC31 SECretory 1273.0 0 0 0 0 -0.4446667765955492 P38968 0.94931298494339 0.956179976463318 0.9475290179252625 0.4742872714996338 0.2910825610160828 0.3492472469806671 50.11415707416666 40.0 1.0 no 1299 chrIV_108313 4077 essential YDL195W 1105 + TCCATTTACAAGCCCCAACT H|370|D H|370|Y F|369|L silent|TTC>TTT|F|369 SEC31 SECretory 1273.0 0 0 0 0 0.5667421095918378 P38968 0.9473130106925964 0.9489949941635132 0.9387490153312684 0.13838787376880646 0.0506717823445797 0.6584360003471375 52.185404573216545 45.0 1.0 no 1300 chrIV_108314r 4078 essential YDL195W 1109 - ACCAAGTTGGGGCTTGTAAA W|376|S W|376|* W|376|C W|376|* SEC31 SECretory 1273.0 0 0 0 0 -4.0448995319774514 P38968 0.8858469724655151 0.8858469724655151 0.0 0.0 0.20200000703334808 0.2160000056028366 0.623740017414093 0.35857999324798584 1.4491000175476074 1.8494800329208372 47.88176477482853 45.0 1.0 yes 1301 chrIV_108319 4080 essential YDL195W 1111 + TACAAGCCCCAACTTGGTAT Q|372|E Q|372|* A|373|G A|373|V SEC31 SECretory 1273.0 0 0 0 0 -2.5962137547889554 P38968 0.9590039849281312 0.9484469890594482 0.9504740238189696 0.30689844489097595 0.12950775027275085 0.04409162700176239 -0.03799999877810478 0.08619999885559082 -0.1225999966263771 0.2074200063943863 50.43073955835166 45.0 1.0 yes 1302 chrIV_108492r 4087 essential YDL195W 1287 - ACCAGTCTTTGATTTATTAA silent|CTG>CTC|L|435 silent|CTG>CTA|L|435 V|436|L V|436|I SEC31 SECretory 1273.0 0 0 0 0 1.1828436884442424 P38968 0.9539830088615416 0.9574310183525084 0.2707880735397339 0.4418965280056 -0.7842000126838684 -0.7369999885559082 -0.6041799783706665 -0.6337000131607056 40.02073573207667 25.0 1.0 no 1303 chrIV_108643r 4089 essential YDL195W 1438 - ATCGTCTTCTTTCTCATTGT D|486|H D|486|N D|485|H D|485|N SEC31 SECretory 1273.0 0 0 0 0 -0.4610431315534167 P38968 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.011192264966666698 0.02620762027800083 0.03307171911001205 0.33758872747421265 -0.707859992980957 -0.6827800273895264 48.60097386549182 35.0 1.0 no 1304 chrIV_108842 4095 essential YDL195W 1634 + TTCAAATAACGAAAGATTAA S|546|* S|546|L SEC31 SECretory 1273.0 0 0 0 0 -1.161334663352123 P38968 0.9298099875450134 0.0198771134018898 -1.589400053024292 -1.7043000459671018 28.61679329030181 20.0 1.0 no 1305 chrIV_109033r 4098 essential YDL195W 1828 - AATCAACATTTCATTCCTCT L|615|F silent|TTG>TTA|L|615 M|614|I M|614|I SEC31 SECretory 1273.0 0 0 0 0 -0.11169451372562887 P38968 0.9587849974632264 0.9553959965705872 0.9553959965705872 0.12659350037574768 0.2015895396471024 0.2015895396471024 0.36059999465942383 0.36059999465942383 1.0012799501419067 1.0012799501419067 42.76020907835544 30.0 1.0 no 1306 chrIV_109164r 4099 essential YDL195W 1959 - TTCAATTTATCCTCCAAATC L|659|F silent|TTG>TTA|L|659 SEC31 SECretory 1273.0 0 0 0 0 -0.3016542975934747 P38968 0.9587849974632264 0.217026561498642 0.8479999899864197 0.2342399954795837 41.08432338548454 30.0 1.0 no 1307 chrIV_109326 4100 essential YDL195W 2118 + ATCAACTTAACTACTTCCAC I|707|M silent|ATC>ATT|I|707 N|708|K silent|AAC>AAT|N|708 SEC31 SECretory 1273.0 0 0 0 0 0.2503505053380666 P38968 0.9598389863967896 0.9439849853515624 0.011263804510235786 0.10336998105049132 0.6615999937057495 -0.7081999778747559 -0.6120200157165527 41.352463760455116 35.0 1.0 no 1308 chrIV_109342r 4101 essential YDL195W 2137 - GGCTAGTTCGAAATTTCCTG A|719|P A|719|T SEC31 SECretory 1273.0 0 0 0 0 -1.5269752203727798 P38968 0.9573720097541808 0.9523990154266356 0.020040150731801987 0.020342523232102398 5.938199996948242 2.573400020599365 46.870170165423524 45.0 1.0 no 1309 chrIV_109521 4107 essential YDL195W 2313 + GTTCCTGTACTACCAACTCC P|773|A P|773|S P|773|R P|773|L SEC31 SECretory 1273.0 0 0 0 0 0.5013810494589477 P38968 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 1.0 0.6446612477302551 0.15327531099319458 0.19893626868724826 53.61705480332579 50.0 1.0 no 1310 chrIV_109556 4108 essential YDL195W 2348 + TACTTCTATTCCTAGTATGC T|784|S T|784|I S|785|C S|785|F SEC31 SECretory 1273.0 0 0 0 0 -0.14152141804611795 P38968 0.9491789937019348 0.9472420215606691 0.945252001285553 0.9294660091400146 0.7252213358879089 0.06301569938659668 0.18639610707759854 0.7097757458686829 45.54913656428642 35.0 1.0 no 1311 chrIV_109836 4115 essential YDL195W 2628 + ACTTTTGCTCCTATACAACC T|877|S T|877|I SEC31 SECretory 1273.0 0 0 0 0 -0.012259441794488436 P38968 0.9491789937019348 0.9472420215606691 0.8000092506408691 0.3013272285461426 47.75127999904693 40.0 1.0 no 1312 chrIV_109910 4119 essential YDL195W 2702 + ACCTCCAATTAATGCTGTAT P|902|R P|902|L P|902|A P|902|S SEC31 SECretory 1273.0 0 0 0 0 -0.4482948315406521 P38968 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.20387457311153406 0.08962306380271913 0.2285879850387573 0.4791751801967621 45.5181384715288 35.0 1.0 no 1313 chrIV_109914r 4121 essential YDL195W 2709 - TGACCCGATACAGCATTAAT G|909|A G|909|D G|909|R G|909|S SEC31 SECretory 1273.0 0 0 0 0 0.6648738074701325 P38968 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.0 0.0 0.0 0.0 0.09700000286102296 0.06027999892830849 -0.046720001846551895 0.10452000051736833 45.33925275248061 40.0 1.0 no 1314 chrIV_110049 4124 essential YDL195W 2841 + TCGACACCAACTCCATTAAA S|948|W S|948|L T|949|R T|949|I SEC31 SECretory 1273.0 0 0 0 0 -0.2719974669419122 P38968 0.9288619756698608 0.9298099875450134 0.9476869702339172 0.9472420215606691 0.02342292852699757 0.3213944137096405 0.07297836244106293 0.04320371150970459 43.67392598833453 40.0 1.0 no 1315 chrIV_114712r 4125 essential YDL193W 43 - TCTATGCGGTTTTTCATTAG R|21|T R|21|K silent|CCG>CCC|P|19 silent|CCG>CCA|P|19 NUS1 Nuclear Undecaprenyl pyrophosphate Synthase 375.0 0 0 0 0 -0.31114717533324 Q12063 0.932735025882721 0.955805003643036 44.3689497260487 35.0 1.0 no 1316 chrIV_114726r 4126 essential YDL193W 57 - TCTCTTTCGATCTTTCTATG R|25|T R|25|K D|26|H D|26|N NUS1 Nuclear Undecaprenyl pyrophosphate Synthase 375.0 0 0 0 0 0.6367477051196988 Q12063 0.932735025882721 0.955805003643036 0.9486550092697144 0.956179976463318 44.32384434512312 35.0 1.0 no 1317 chrIV_114771 4128 essential YDL193W 99 + CACATCCCACCTCCAGAATC H|34|Q silent|CAC>CAT|H|34 I|35|M silent|ATC>ATT|I|35 NUS1 Nuclear Undecaprenyl pyrophosphate Synthase 375.0 0 0 0 0 0.3910420925568481 Q12063 0.9588389992713928 0.9598389863967896 54.709884474949554 55.00000000000001 1.0 no 1318 chrIV_114783r 4132 essential YDL193W 114 - CCCTTTAAAACACCAGATTC K|44|N silent|AAG>AAA|K|44 G|45|R G|45|S NUS1 Nuclear Undecaprenyl pyrophosphate Synthase 375.0 0 0 0 0 -0.7485562651726291 Q12063 0.9355990290641784 0.941340982913971 0.951104998588562 0.4861021041870117 0.3108462393283844 0.7251096367835999 44.06031658827538 40.0 1.0 no 1319 chrIV_114876r 4136 essential YDL193W 207 - TCATTGTTCACTTTCTTCTG E|76|Q E|76|K NUS1 Nuclear Undecaprenyl pyrophosphate Synthase 375.0 0 0 0 0 0.1437991349539591 Q12063 0.956179976463318 0.9475290179252625 0.5793737769126892 0.8895775675773621 45.59948585700437 35.0 1.0 no 1320 chrIV_114911r 4137 essential YDL193W 242 - AATCTTCTGTCTTTTGCTTT D|87|H D|87|N E|86|Q E|86|K NUS1 Nuclear Undecaprenyl pyrophosphate Synthase 375.0 0 0 0 0 0.35315755681861605 Q12063 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.13781501352787018 0.5792287588119507 0.5871005654335022 0.9236403107643129 45.746143098111645 30.0 1.0 no 1321 chrIV_114994 4138 essential YDL193W 322 + ACATCTGCTTCGGGTTGTTT Y|108|* silent|TAC>TAT|Y|108 I|109|M silent|ATC>ATT|I|109 NUS1 Nuclear Undecaprenyl pyrophosphate Synthase 375.0 0 0 0 0 -0.3242693373465442 Q12063 0.9598389863967896 0.12539255619049072 52.74063700119757 45.0 1.0 no 1322 chrIV_115086r 4141 essential YDL193W 417 - ACGTCCTGTCTAATCAACTG V|146|L V|146|I D|145|H D|145|N NUS1 Nuclear Undecaprenyl pyrophosphate Synthase 375.0 0 0 0 0 0.4986805870412243 Q12063 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 0.07583796977996826 0.6292887926101685 0.0 0.0 46.31564457315568 45.0 1.0 no 1323 chrIV_115114 4143 essential YDL193W 442 + CTCTGAAAAAAATTCCTAAA L|149|V silent|CTG>TTG|L|149 NUS1 Nuclear Undecaprenyl pyrophosphate Synthase 375.0 0 0 0 0 0.3368252246338421 Q12063 0.9512209892272948 0.0 31.55076405360484 25.0 1.0 no 1324 chrIV_115141r 4144 essential YDL193W 472 - TGGCTTGACTTCCAAGATAG K|163|N silent|AAG>AAA|K|163 NUS1 Nuclear Undecaprenyl pyrophosphate Synthase 375.0 0 0 0 0 0.9598081950725088 Q12063 0.9355990290641784 0.013112484477460384 46.477278663613326 45.0 1.0 no 1325 chrIV_115341r 4151 essential YDL193W 672 - GCGTAGTTTGGAACATGAGC A|231|P A|231|T NUS1 Nuclear Undecaprenyl pyrophosphate Synthase 375.0 0 0 0 0 -0.7385746255993112 Q12063 0.9573720097541808 0.9523990154266356 0.2002282589673996 0.7466719746589661 47.964305731836184 50.0 1.0 no 1326 chrIV_115417r 4152 essential YDL193W 748 - CTCATTGCCTACATCAGTCT E|256|Q E|256|K NUS1 Nuclear Undecaprenyl pyrophosphate Synthase 375.0 0 0 0 0 -0.36536662456801977 Q12063 0.956179976463318 0.9475290179252625 0.5379716157913208 0.4487665891647339 52.2436540602124 45.0 1.0 no 1327 chrIV_115517 4153 essential YDL193W 845 + TGTCGATCTGACCAAAACTA silent|GTC>GTG|V|283 silent|GTC>GTT|V|283 NUS1 Nuclear Undecaprenyl pyrophosphate Synthase 375.0 0 0 0 0 0.48158683482743 Q12063 42.13165293600679 40.0 1.0 no 1328 chrIV_115451r 4154 essential YDL193W 782 - TAGCAATTTTGTCCTTTTCT A|267|P A|267|T NUS1 Nuclear Undecaprenyl pyrophosphate Synthase 375.0 0 0 0 0 0.642219546010456 Q12063 0.9573720097541808 0.9523990154266356 0.32864582538604736 0.6687344908714294 45.759171453643255 30.0 1.0 no 1329 chrIV_126954r 4158 high_effect YDL185W 170 - TTCTAATGACTTCACCCACC R|63|T R|63|K VMA1 Vacuolar Membrane Atpase 1071.0 0 0 0 0 0.1764681631547741 P17255 0.9788659811019896 0.9986129999160768 0.006359724327921867 0.0329647995531559 49.77563957797355 45.0 1.0 no 1330 chrIV_127039r 4163 high_effect YDL185W 255 - GGCTTACCTGTTCTCAAAAC K|91|N silent|AAG>AAA|K|91 G|90|A G|90|D VMA1 Vacuolar Membrane Atpase 1071.0 1 Series([], Name: modification, dtype: object) 0 0 0 1.1789880194958315 P17255 0.9806249737739564 0.9901490211486816 0.9780880212783812 0.03155713900923729 0.01123762410134077 0.008164233528077602 46.63817512432638 45.0 1.0 no 1331 chrIV_127120r 4167 high_effect YDL185W 336 - TCTTCCTTAATGGCTTTCAA E|119|Q E|119|K E|118|Q E|118|K VMA1 Vacuolar Membrane Atpase 1071.0 0 1 0 0 -0.7622112948030062 P17255 1.0002599954605105 0.9889079928398132 1.0004899501800537 0.9891330003738404 0.6014595627784729 0.9208118319511414 0.16524581611156464 0.30944427847862244 46.286012179213905 35.0 1.0 no 1332 chrIV_127197 4170 high_effect YDL185W 410 + TATCAAGTGGCAATTTACTC I|138|M silent|ATC>ATT|I|138 VMA1 Vacuolar Membrane Atpase 1071.0 0 1 0 0 -0.6839308215872312 P17255 1.0025700330734253 0.18208035826683044 41.01256055592279 35.0 1.0 no 1333 chrIV_127333 4175 high_effect YDL185W 546 + ATCACTTGGATTGCTCCAGC I|183|M silent|ATC>ATT|I|183 T|184|S T|184|I VMA1 Vacuolar Membrane Atpase 1071.0 0 0 0 0 0.36633776501267146 P17255 1.0025700330734253 0.9910879731178284 0.9891359806060792 0.003685589646920562 0.17409230768680573 0.0317695327103138 53.56943442512914 50.0 1.0 no 1334 chrIV_127453r 4181 high_effect YDL185W 669 - GCAGATAACTTTTCAGTAAC A|230|P A|230|T VMA1 Vacuolar Membrane Atpase 1071.0 0 1 0 0 0.043814037188179784 P17255 1.002079963684082 0.9944819808006288 0.3857005536556244 0.0456574521958828 39.5852871289332 35.0 1.0 no 1335 chrIV_127474 4182 high_effect YDL185W 687 + GCTGACTATCCTTTGTTAAC A|230|G A|230|V D|231|E silent|GAC>GAT|D|231 VMA1 Vacuolar Membrane Atpase 1071.0 0 1 0 0 -0.929715959418882 P17255 0.9928870201110841 0.992114007472992 0.995244026184082 0.12859691679477692 0.03876066952943802 0.1316387951374054 45.961691908541574 40.0 1.0 no 1336 chrIV_127483r 4183 high_effect YDL185W 699 - ACTCTTTGACCTGTTAACAA R|239|T R|239|K V|240|L V|240|I VMA1 Vacuolar Membrane Atpase 1071.0 0 0 0 0 1.0211761688152892 P17255 0.9851019978523254 1.0048500299453735 1.0000799894332886 1.0070600509643557 0.0 0.0 0.010223190300166609 0.09634038060903548 43.102935706495096 35.0 1.0 no 1337 chrIV_127513 4184 high_effect YDL185W 726 + GCTTTGTTTCCTTGTGTTCA A|243|G A|243|V VMA1 Vacuolar Membrane Atpase 1071.0 0 0 0 0 0.5493565815695558 P17255 0.9916989803314208 0.9909250140190125 0.023436220362782482 0.0649198591709137 53.644063244179506 40.0 1.0 no 1338 chrIV_127552r 4187 high_effect YDL185W 768 - TTACCACAACCAAAAGCACC G|262|A G|262|D G|262|R G|262|S VMA1 Vacuolar Membrane Atpase 1071.0 0 0 0 0 -1.2366223590651777 P17255 0.9963840246200562 0.984323024749756 0.978958010673523 0.9976239800453186 0.0 0.0 0.0 0.0 45.06039898047106 45.0 1.0 no 1339 chrIV_127692 4192 high_effect YDL185W 905 + AAACATTGAGGTTGGTAATA N|303|K silent|AAC>AAT|N|303 VMA1 Vacuolar Membrane Atpase 1071.0 0 0 0 0 1.0691697665085809 P17255 0.940957009792328 0.8356981873512268 0.08263999968767166 37.152580125762256 30.0 1.0 no 1340 chrIV_127809r 4195 high_effect YDL185W 1025 - CACGACTTGAGTCACTTTTG R|348|P R|348|H S|347|T S|347|N VMA1 Vacuolar Membrane Atpase 1071.0 0 1 0 0 0.8750022812058662 P17255 0.9393370151519777 0.9690049886703492 0.975284993648529 0.9761030077934264 0.2124245762825012 0.16958294808864596 0.5300981998443604 0.4365245997905731 0.012199999764561651 -0.24779999256134036 45.08260138004061 45.0 1.0 no 1341 chrIV_127905 4197 high_effect YDL185W 1118 + CCGTTTGTCTCGTACCATTA R|374|G R|374|C VMA1 Vacuolar Membrane Atpase 1071.0 0 1 0 0 0.25141435928341954 P17255 0.9380459785461426 0.9352790117263794 1.240339994430542 0.3322800099849701 1.7461999654769895 0.33219999074935913 52.01582956058502 45.0 1.0 no 1342 chrIV_127978r 4201 high_effect YDL185W 1194 - AGCTCAACAATTCTACCGTC E|404|D silent|GAG>GAA|E|404 E|404|Q E|404|K VMA1 Vacuolar Membrane Atpase 1071.0 0 1 0 0 -1.0901974556844294 P17255 0.9202479720115662 0.9265930056571959 0.8951629996299744 0.3912495374679565 0.5161020159721375 0.9946234822273254 0.09842000156641006 0.02353999949991703 -0.16898000240325928 47.25606643209914 45.0 1.0 no 1343 chrIV_127979r 4202 high_effect YDL185W 1195 - AAGCTCAACAATTCTACCGT E|404|D silent|GAG>GAA|E|404 E|404|Q E|404|K VMA1 Vacuolar Membrane Atpase 1071.0 0 1 0 0 0.8722305217381532 P17255 0.9202479720115662 0.9265930056571959 0.8951629996299744 0.3912495374679565 0.5161020159721375 0.9946234822273254 0.09842000156641006 0.02353999949991703 -0.16898000240325928 44.78555582289931 40.0 1.0 no 1344 chrIV_128041r 4205 high_effect YDL185W 1257 - ACTAATTCGTTGGCTCTCTC V|426|L V|426|I VMA1 Vacuolar Membrane Atpase 1071.0 0 0 0 0 -0.7538379554385115 P17255 0.9525160193443298 0.9661740064620972 0.3265569806098938 0.20503905415534973 0.2659800052642822 0.19298000633716586 -1.4453999996185305 -1.4462000131607056 49.360843532241574 45.0 1.0 no 1345 chrIV_128488r 4210 high_effect YDL185W 1704 - CCAACAATAGCGTCCCATAA G|575|R G|575|S V|574|L V|574|I VMA1 Vacuolar Membrane Atpase 1071.0 0 0 0 0 0.8053367805438792 P17255 0.9246039986610411 0.9383580088615416 0.9625340104103088 0.9726319909095764 0.5593239665031433 0.7344265580177307 0.3071749806404114 0.18369141221046448 2.341660022735596 1.2492799758911133 -0.8343200087547302 -0.34130001068115234 -1.4323999881744385 -1.0607999563217163 47.520314958889166 45.0 1.0 no 1346 chrIV_128575 4212 high_effect YDL185W 1788 + ACTCGTGAAACATTTCTTGC R|598|G R|598|C T|597|S T|597|I VMA1 Vacuolar Membrane Atpase 1071.0 0 0 0 0 0.6324097636441988 P17255 0.7305939793586731 0.6804289817810059 0.8175410032272339 0.7602649927139282 0.04818280041217804 0.0067440071143209926 0.25127553939819336 0.11654096841812135 5.00685977935791 3.322700023651123 0.25534000992774963 -1.8415800333023071 43.404980425149965 40.0 1.0 no 1347 chrIV_128659 4215 high_effect YDL185W 1872 + ATTCATACTTCTGTCAGAGA H|626|D H|626|Y VMA1 Vacuolar Membrane Atpase 1071.0 0 1 0 0 0.4177880790404191 P17255 0.9078969955444336 0.9096230268478394 0.2905941903591156 1.0 -0.7545599937438965 -1.6867200136184692 -4.23420000076294 -1.4944000244140625 43.8466059499375 35.0 1.0 no 1348 chrIV_128664 4216 high_effect YDL185W 1877 + TACTTCTGTCAGAGATGGTT T|627|S T|627|I S|628|C S|628|F VMA1 Vacuolar Membrane Atpase 1071.0 0 1 0 0 -1.0378318051232678 P17255 0.9025610089302064 0.8869990110397339 0.7837179899215698 0.7642319798469543 0.3714396059513092 0.11203955113887787 0.05079928785562515 0.04842618852853775 0.21352000534534452 -0.709119975566864 0.1350799947977066 -0.9173399806022644 46.73398888452266 40.0 1.0 no 1349 chrIV_128734r 4219 high_effect YDL185W 1950 - CCATTCATGTCAACCTTAGC G|657|R G|657|S M|655|I M|655|I VMA1 Vacuolar Membrane Atpase 1071.0 0 0 0 0 0.9616099823478992 P17255 0.9580469727516174 0.9705550074577332 0.9772379994392396 0.9772379994392396 0.015621377155184748 0.05780062824487686 0.43514925241470337 0.43514925241470337 0.07419999688863754 0.07419999688863754 49.75755784718672 45.0 1.0 no 1350 chrIV_128812 4221 high_effect YDL185W 2025 + AACGTTCTTTCGAAGTGTGC N|676|K silent|AAC>AAT|N|676 L|678|V L|678|F VMA1 Vacuolar Membrane Atpase 1071.0 0 0 0 0 0.1141327732353414 P17255 0.7051050066947937 0.8218899965286255 0.8330979943275452 0.4432784616947174 0.1480051428079605 0.08737499266862869 0.3212200105190277 3.805959939956665 3.4929399490356445 46.12421321443093 45.0 1.0 no 1351 chrIV_129105 4230 high_effect YDL185W 2318 + CGCTAATACATCTAACATGC A|774|G A|774|V VMA1 Vacuolar Membrane Atpase 1071.0 0 1 0 0 -0.2400124002467232 P17255 0.9483640193939208 0.9499040246009828 0.0 0.0 41.39609978580319 40.0 1.0 no 1352 chrIV_163652r 4235 essential YDL166C 368 + AAACCTCGATGCCGAGATTA N|124|K silent|AAC>AAT|N|124 L|125|V L|125|F FAP7 Factor Activating Pos9 197.0 0 0 0 0 -0.2578582806269226 Q12055 0.8622270226478577 1.1010700464248655 0.942035973072052 0.0038034792523831133 0.8684772849082947 0.057378634810447686 1.0986399650573728 2.3727400302886963 46.381238338405296 45.0 0.0 no 1353 chrIV_163754 4237 essential YDL166C 269 - CCAAGTCAATCAGCCTCTCT L|96|F silent|TTG>TTA|L|96 D|95|H D|95|N FAP7 Factor Activating Pos9 197.0 0 0 0 0 0.6220051833144611 Q12055 0.8777769804000854 0.9085109829902648 0.9222260117530824 0.02076576091349125 0.1859092861413956 0.08422383666038513 53.64695003121466 50.0 0.0 no 1354 chrIV_163893 4242 essential YDL166C 130 - TTCGAAACAGTCGTTATCTT E|50|Q E|50|K FAP7 Factor Activating Pos9 197.0 0 0 0 0 -0.3133565078969912 Q12055 1.0335299968719482 1.0433399677276611 0.03765450045466423 0.04126091673970223 41.78971330825669 35.0 0.0 no 1355 chrIV_163922r 4243 essential YDL166C 98 + TTACAAATACTATAACATTT Y|34|* silent|TAC>TAT|Y|34 FAP7 Factor Activating Pos9 197.0 0 1 0 0 0.2479158317528281 Q12055 30.055472235121158 15.0 0.0 no 1356 chrIV_164325r 4246 essential YDL165W 38 - GTTCTTTGTCCTCTAGCTTA E|19|Q E|19|K CDC36 Cell Division Cycle 191.0 0 1 0 0 0.8328401170874458 P06100 0.956179976463318 0.9475290179252625 0.031761392951011665 0.02777812443673611 52.97715112763665 40.0 1.0 no 1357 chrIV_164364 4247 essential YDL165W 74 + CCATTCCATGACCTTAGGAG H|26|D H|26|Y S|27|C S|27|F CDC36 Cell Division Cycle 191.0 0 0 0 0 -3.4557602322372074 P06100 0.9473130106925964 0.9489949941635132 0.945252001285553 0.9294660091400146 -0.3752375841140747 -0.6040746569633484 51.35802780354413 50.0 1.0 yes 1358 chrIV_164391 4249 essential YDL165W 101 + ATCGTCGATGCTATATTCGT S|35|W S|35|L S|36|W S|36|L CDC36 Cell Division Cycle 191.0 0 0 0 0 0.2351779769946877 P06100 0.9288619756698608 0.9298099875450134 0.9288619756698608 0.9298099875450134 0.005086231045424938 0.02014325186610222 0.19093972444534305 0.8752251863479614 0.1429399996995926 -0.3984799981117249 -0.30153998732566833 -0.7342200279235841 46.67819645806578 40.0 1.0 no 1359 chrIV_164392 4250 essential YDL165W 102 + TCGTCGATGCTATATTCGTT S|35|W S|35|L S|36|W S|36|L CDC36 Cell Division Cycle 191.0 0 0 0 0 -0.42418952577852576 P06100 0.9288619756698608 0.9298099875450134 0.9288619756698608 0.9298099875450134 0.005086231045424938 0.02014325186610222 0.19093972444534305 0.8752251863479614 0.1429399996995926 -0.3984799981117249 -0.30153998732566833 -0.7342200279235841 46.947333357275575 40.0 1.0 no 1360 chrIV_164658 4257 essential YDL165W 368 + CATCCAGGAACTAACGTATT I|124|M silent|ATC>ATT|I|124 Q|125|E Q|125|* CDC36 Cell Division Cycle 191.0 0 0 0 0 0.6137622195252109 P06100 0.9598389863967896 0.9590039849281312 0.4592917859554291 0.0 1.2138400077819824 0.8446599841117859 -0.6780999898910522 1.3935199975967407 43.02375843435607 40.0 1.0 no 1361 chrIV_164661r 4258 essential YDL165W 374 - GTTCCAAATACGTTAGTTCC E|131|Q E|131|K L|130|F silent|TTG>TTA|L|130 CDC36 Cell Division Cycle 191.0 0 0 0 0 -0.21325687716123504 P06100 0.956179976463318 0.9475290179252625 0.9587849974632264 0.13883279263973236 0.028670867905020717 0.17044074833393094 0.17973999679088593 0.7277799844741821 0.4029799997806549 -0.5177199840545654 -0.0774800032377243 46.116012363241616 40.0 1.0 no 1362 chrIV_164666 4259 essential YDL165W 376 + AACTAACGTATTTGGAACTC L|127|V silent|CTA>TTA|L|127 T|128|R T|128|M CDC36 Cell Division Cycle 191.0 0 0 0 0 -0.3440042303717196 P06100 0.9512209892272948 0.9476869702339172 0.9502379894256592 0.16544495522975922 0.013617095537483692 0.010465807281434536 2.1262400150299072 9.323320388793944 0.5792999863624573 1.0276199579238892 5.039460182189941 0.8482999801635742 37.822928414166476 35.0 1.0 no 1363 chrIV_165917 4269 essential YDL164C 1318 - AGTCATATTCTCGCCATTTC M|445|I M|445|I CDC9 Cell Division Cycle 755.0 0 0 0 0 1.2219281127968404 P04819 0.3876543939113617 0.3876543939113617 49.36755162240149 40.0 0.0 no 1364 chrIV_166041 4271 essential YDL164C 1194 - ACTTCATTAATTGCCTTGGT V|405|L V|405|I E|404|Q E|404|K CDC9 Cell Division Cycle 755.0 0 0 0 0 1.3059195362142209 P04819 0.0753413513302803 0.01873786933720112 0.006853906437754631 0.0053051533177495 46.998064472089936 35.0 0.0 no 1365 chrIV_166206 4272 essential YDL164C 1029 - GCACTTTCTAACACATCCAT S|349|T S|349|N A|350|P A|350|T CDC9 Cell Division Cycle 755.0 0 0 0 0 -1.3659430178836385 P04819 0.20904403924942014 0.3591113090515137 0.12332551926374435 0.3301200270652771 47.32995423209872 40.0 0.0 no 1366 chrIV_166205 4273 essential YDL164C 1030 - AGCACTTTCTAACACATCCA A|350|P A|350|T S|349|T S|349|N CDC9 Cell Division Cycle 755.0 0 0 0 0 -0.4468673515722735 P04819 0.12332551926374435 0.3301200270652771 0.20904403924942014 0.3591113090515137 47.420286753185955 40.0 0.0 no 1367 chrIV_166470r 4281 essential YDL164C 762 + AAGCCCAAACCCTTGACCGT P|256|A P|256|S P|256|R P|256|L CDC9 Cell Division Cycle 755.0 0 0 0 0 0.5342516719242122 P04819 0.12345302850008012 0.11743605881929398 0.05163304880261421 0.1099996268749237 55.112321637965294 55.00000000000001 0.0 no 1368 chrIV_166544r 4283 essential YDL164C 688 + AACTTAAATACAAGGATATT L|231|V L|231|F CDC9 Cell Division Cycle 755.0 0 0 0 0 -0.04806931363709588 P04819 0.2334495633840561 0.04443836957216263 30.86480515298621 20.0 0.0 no 1369 chrIV_166583 4285 essential YDL164C 652 - TTTCCCGCAAGTTTCGCTTA silent|GGG>GGC|G|223 silent|GGG>GGA|G|223 G|223|A G|223|E CDC9 Cell Division Cycle 755.0 0 0 0 0 0.6574833578920298 P04819 0.0 0.0 53.17872693276638 45.0 0.0 no 1370 chrIV_166639 4288 essential YDL164C 596 - CCAAGCCTGCTTCGTAGTCA L|205|F silent|TTG>TTA|L|205 G|204|A G|204|D CDC9 Cell Division Cycle 755.0 0 0 0 0 -0.1253378129398331 P04819 0.018251879140734676 0.004110005218535662 0.055550217628479004 57.03379392535107 55.00000000000001 0.0 no 1371 chrIV_166663r 4290 essential YDL164C 569 + ATACCTTTTCATCAATAGAT Y|191|* silent|TAC>TAT|Y|191 L|192|V L|192|F CDC9 Cell Division Cycle 755.0 0 0 0 0 -1.2584605703863516 P04819 0.011117169633507729 0.010552866384387016 39.33484130278914 25.0 0.0 no 1372 chrIV_166795 4293 essential YDL164C 440 - CCTCACAAACTTCAGAATAG E|153|Q E|153|K E|153|D silent|GAG>GAA|E|153 CDC9 Cell Division Cycle 755.0 0 0 0 0 0.0761624632177979 P04819 0.15016789734363556 0.9622012376785278 0.06397422403097153 40.21046606271312 40.0 0.0 no 1373 chrIV_166876r 4295 essential YDL164C 356 + ACCGCAACAATCTCAGAGGT P|120|R P|120|L P|120|A P|120|S CDC9 Cell Division Cycle 755.0 0 1 0 0 -4.429457188806656 P04819 0.4601321816444397 0.3190435469150543 0.6928319334983826 0.6842754483222961 49.5615816773028 50.0 0.0 yes 1374 chrIV_166911r 4301 essential YDL164C 321 + CCATCATCCGCTCCCTCTTC P|108|R P|108|L S|109|* S|109|L CDC9 Cell Division Cycle 755.0 0 0 0 0 0.13607902163243846 P04819 0.4966732561588288 0.3018922507762909 0.3330700695514679 62.4356060384867 60.0 0.0 no 1375 chrIV_167045 4302 essential YDL164C 190 - TCTATCTTCCAGCATATGTT R|70|T R|70|K D|69|H D|69|N CDC9 Cell Division Cycle 755.0 0 0 0 0 -1.0378656960573531 P04819 0.4713595807552338 0.8034989237785339 0.13018125295639038 0.5011330842971802 48.16246175151622 35.0 0.0 no 1376 chrIV_167093 4303 essential YDL164C 142 - TTCTGTTGGCTTATTTTTCA E|54|Q E|54|K CDC9 Cell Division Cycle 755.0 0 1 0 0 0.4935045337935393 P04819 0.5229136943817139 0.788223147392273 46.0956471477777 30.0 0.0 no 1377 chrIV_167157r 4307 essential YDL164C 75 + TCCTCATTACCTTCCTCTGC silent|TCC>TCG|S|26 silent|TCC>TCT|S|26 S|26|C S|26|F CDC9 Cell Division Cycle 755.0 0 0 0 0 -0.7587121790039795 P04819 0.08968684822320938 0.22326467931270602 57.861569861413564 50.0 0.0 no 1378 chrIV_170919r 4311 high_effect YDL160C 989 + TCAAGGTAAGGTTCGTACAT Q|331|E Q|331|* DHH1 DEAD box Helicase Homolog 506.0 0 0 0 0 -0.9557718799753864 P39517 0.3790296912193297 0.02807999961078167 44.0856736490552 40.0 0.0 no 1379 chrIV_170931r 4312 high_effect YDL160C 977 + CCACGAATTTCGTCAAGGTA H|327|Q silent|CAC>CAT|H|327 H|327|D H|327|Y DHH1 DEAD box Helicase Homolog 506.0 0 1 0 0 -0.14400388059585315 P39517 0.31369468569755554 0.09495346248149872 0.033375225961208344 -0.4559600055217743 2.3528599739074707 -0.7397999763488771 46.09352408224628 45.0 0.0 no 1380 chrIV_170931 4313 high_effect YDL160C 980 - CCTTACCTTGACGAAATTCG K|333|N silent|AAG>AAA|K|333 G|332|A G|332|D DHH1 DEAD box Helicase Homolog 506.0 0 0 0 0 0.9158530553090842 P39517 0.5048612356185913 0.04670558124780655 0.0060477377846837035 0.8086199760437012 3.899399995803833 5.030720233917236 44.496531740183116 45.0 0.0 no 1381 chrIV_171010 4314 high_effect YDL160C 901 - GCCTAAATCAGTGATTTTCT G|307|R G|307|S G|307|A G|307|D DHH1 DEAD box Helicase Homolog 506.0 0 0 0 0 0.4392408190667153 P39517 0.02152924053370953 0.08110453188419342 0.030593095347285267 0.5092412829399109 1.788100004196167 3.6479198932647705 3.496000051498413 5.013160228729248 44.604060874674815 35.0 0.0 no 1382 chrIV_171027 4315 high_effect YDL160C 884 - TCTTGGCTAGTAATTCGACA K|301|N silent|AAG>AAA|K|301 A|300|P A|300|T DHH1 DEAD box Helicase Homolog 506.0 0 0 0 0 0.3816061505845417 P39517 0.14276373386383054 0.019000111147761345 0.8380383253097534 0.3108800053596497 5.238480091094972 0.04912000149488449 45.561079079159136 40.0 0.0 no 1383 chrIV_171179 4316 high_effect YDL160C 732 - TCCATCAAATTAATTTCATA M|250|I M|250|I E|251|Q E|251|K DHH1 DEAD box Helicase Homolog 506.0 0 0 0 0 0.17400755359656933 P39517 0.05361168459057808 0.05361168459057808 0.007434210740029813 0.036067645996809006 0.5753600001335144 0.5753600001335144 0.1475600004196167 0.540120005607605 35.53078348075826 20.0 0.0 no 1384 chrIV_171228r 4318 high_effect YDL160C 680 + TACTTTCCCACTAACGGTTA T|228|S T|228|I F|229|L silent|TTC>TTT|F|229 DHH1 DEAD box Helicase Homolog 506.0 0 0 0 0 0.7159291246974566 P39517 0.0 0.0 0.9527253508567809 0.2759400010108948 0.03254000097513199 1.4212599992752075 0.9455440044403076 47.793135007867924 40.0 0.0 no 1385 chrIV_171492r 4322 high_effect YDL160C 416 + ACACTGTGGTATTTCATGTA H|140|Q silent|CAC>CAT|H|140 H|140|D H|140|Y DHH1 DEAD box Helicase Homolog 506.0 0 0 0 0 -0.2779761115387006 P39517 0.01644239015877247 0.01146457623690367 0.871342658996582 0.4894199967384338 0.7837399840354919 -1.8578200340271 0.4641799926757813 0.8685240149497986 -1.0158419609069824 44.93287453515751 35.0 0.0 no 1386 chrIV_171544 4324 high_effect YDL160C 367 - TTGCAGAGCTAACTCTCTTG silent|CTG>CTC|L|128 silent|CTG>CTA|L|128 DHH1 DEAD box Helicase Homolog 506.0 0 0 0 0 0.9258860128150576 P39517 47.441828075916526 45.0 0.0 no 1387 chrIV_171545 4325 high_effect YDL160C 366 - TGCAGAGCTAACTCTCTTGT silent|CTG>CTC|L|128 silent|CTG>CTA|L|128 DHH1 DEAD box Helicase Homolog 506.0 0 0 0 0 0.08693022382985027 P39517 49.923745816196345 45.0 0.0 no 1388 chrIV_171646 4327 high_effect YDL160C 265 - ACCTGTACCATTCTTTGCTC G|95|R G|95|S G|95|A G|95|D DHH1 DEAD box Helicase Homolog 506.0 0 0 0 0 -1.964433344567192 P39517 0.0 0.0 0.0 0.0 7.514259815216064 4.101679801940918 3.0438199043273926 3.27649998664856 53.28554516094231 45.0 0.0 no 1389 chrIV_182166r 4337 essential YDL153C 830 + CACATCTATGAAGGGACATC T|278|R T|278|I S|279|C S|279|F SAS10 Something About Silencing 610.0 0 0 0 0 0.8755046024094195 Q12136 0.9476869702339172 0.9472420215606691 0.945252001285553 0.9294660091400146 0.263876736164093 0.2633702158927917 0.008743224665522575 0.005156680010259152 43.02934910094484 45.0 0.0 no 1390 chrIV_182303 4339 essential YDL153C 696 - TTCTTTAATTCGTCAAACTT K|238|N silent|AAG>AAA|K|238 SAS10 Something About Silencing 610.0 0 0 0 0 -0.3507272199513731 Q12136 0.9355990290641784 0.1797391027212143 37.712229089785644 25.0 0.0 no 1391 chrIV_182627r 4343 essential YDL153C 369 + TCCACAAAAGGAGAATATTA silent|TCC>TCG|S|124 silent|TCC>TCT|S|124 S|124|C S|124|F SAS10 Something About Silencing 610.0 0 0 0 0 0.8371174815572688 Q12136 0.945252001285553 0.9294660091400146 0.04730134829878807 0.034269768744707114 35.91209726898757 30.0 0.0 no 1392 chrIV_182678 4344 essential YDL153C 321 - CCATTCTCTTCATCTTCCTC G|114|R G|114|S E|112|D silent|GAG>GAA|E|112 SAS10 Something About Silencing 610.0 0 0 0 0 -0.23618536947478924 Q12136 0.941340982913971 0.951104998588562 0.94931298494339 0.1860893964767456 0.317471981048584 0.3634152412414551 54.223904112476255 45.0 0.0 no 1393 chrIV_182872 4347 essential YDL153C 127 - ATCTTTATTACTGTCGCCAA D|49|H D|49|N SAS10 Something About Silencing 610.0 0 0 0 0 0.6028151365247086 Q12136 0.9486550092697144 0.956179976463318 0.2258899211883545 0.5376979112625122 45.96304938389017 35.0 0.0 no 1394 chrIV_182888r 4348 essential YDL153C 108 + TTACTTGGACAATCCACCTT L|38|V L|38|F SAS10 Something About Silencing 610.0 0 0 0 0 0.9440417562370264 Q12136 0.9512209892272948 0.9587849974632264 0.037005413323640816 0.1828796863555908 47.687597623846045 40.0 0.0 no 1395 chrIV_182965 4349 essential YDL153C 34 - AATCTCATCCCCAACTTCAG E|17|D silent|GAG>GAA|E|17 E|17|Q E|17|K SAS10 Something About Silencing 610.0 0 1 0 0 -0.2446071126578576 Q12136 0.94931298494339 0.956179976463318 0.9475290179252625 0.8419511318206787 0.459065854549408 0.26658302545547485 49.80138211655651 45.0 0.0 no 1396 chrIV_182973r 4350 essential YDL153C 23 + AACTAAGACCTCTGAAGTTG T|9|S T|9|I SAS10 Something About Silencing 610.0 0 1 0 0 -0.44034839404617054 Q12136 0.9491789937019348 0.9472420215606691 1.0 0.1896963119506836 40.718603978624635 40.0 0.0 no 1397 chrIV_183480 4354 essential YDL150W 137 + TGCGTCCAAAGTAAAGCTAG A|47|G A|47|V S|48|C S|48|F RPC53 RNA Polymerase C 422.0 0 0 0 0 0.3186533322075076 P25441 0.0574401281774044 1.0 0.06663225591182709 0.0443173348903656 43.80330799880681 45.0 1.0 no 1398 chrIV_183604 4358 essential YDL150W 261 + AACACACACGTTATCTCTAG N|88|K silent|AAC>AAT|N|88 T|89|R T|89|I RPC53 RNA Polymerase C 422.0 0 1 0 0 0.06192936166803676 P25441 0.0 0.0 0.0 42.03282950110514 40.0 1.0 no 1399 chrIV_183628r 4361 essential YDL150W 288 - ACAAAGTTCCCAGCCGCCAA V|103|L V|103|I RPC53 RNA Polymerase C 422.0 0 1 0 0 0.15802578639573986 P25441 0.3337657153606415 0.5340664386749268 55.468615209219024 55.00000000000001 1.0 no 1400 chrIV_183679 4362 essential YDL150W 336 + TTCATCAAATCAGAAGGAAG F|113|L silent|TTC>TTT|F|113 I|114|M silent|ATC>ATT|I|114 RPC53 RNA Polymerase C 422.0 0 1 0 0 0.34602157531425537 P25441 0.0 0.029072573408484462 35.65694013439213 35.0 1.0 no 1401 chrIV_183957r 4369 essential YDL150W 617 - CAACGTCTTCGTGTCTTACG V|212|L V|212|I D|211|H D|211|N RPC53 RNA Polymerase C 422.0 0 0 0 0 0.8175818720040369 P25441 0.27127841114997864 0.7416704297065735 0.011547813192009926 0.028582114726305008 47.61260548432267 50.0 1.0 no 1402 chrIV_184039r 4373 essential YDL150W 699 - ACAGGCTCTGTCTTCACACT V|240|L V|240|I E|238|D silent|GAG>GAA|E|238 RPC53 RNA Polymerase C 422.0 0 0 0 0 -1.0131162400584093 P25441 0.3039757013320923 0.19233720004558566 0.5934546589851379 54.455133628707934 50.0 1.0 no 1403 chrIV_188790r 4379 essential YDL148C 1774 + GACTAGACTCTTACGAGTTG L|593|V silent|CTA>TTA|L|593 NOP14 NucleOlar Protein 810.0 0 0 0 0 -0.6478920883706776 Q99207 0.3269824087619781 43.90534942135719 45.0 0.0 no 1404 chrIV_188987 4383 essential YDL148C 1580 - ACTTGATTTGTTCCAGGAAC K|533|N silent|AAG>AAA|K|533 NOP14 NucleOlar Protein 810.0 0 0 0 0 -0.2086211183024773 Q99207 0.4739421904087066 44.99268881885757 40.0 0.0 no 1405 chrIV_189183 4387 essential YDL148C 1384 - TCTATTATATTTCTCTGAAA R|468|T R|468|K NOP14 NucleOlar Protein 810.0 0 0 0 0 1.7497963184540029 Q99207 0.5158742666244507 0.8847734928131104 34.75447918637741 20.0 0.0 no 1406 chrIV_189640r 4388 essential YDL148C 924 + CAGCGTCTTGATCGTATGAA R|310|G R|310|C L|311|V L|311|F NOP14 NucleOlar Protein 810.0 0 0 0 0 -1.020903978911712 Q99207 0.0 0.0 0.19017821550369265 0.07102924585342407 46.08969066802649 45.0 0.0 no 1407 chrIV_189774 4391 essential YDL148C 793 - ATCATACTCCTTATCTAGAT D|271|H D|271|N E|269|D silent|GAG>GAA|E|269 NOP14 NucleOlar Protein 810.0 0 0 0 0 0.8684123143625849 Q99207 0.006245979107916354 0.01885601133108139 0.5260463356971741 43.01733792028682 30.0 0.0 no 1408 chrIV_189782r 4393 essential YDL148C 782 + ACCTAAGACCGATCTAGATA P|262|R P|262|L P|262|A P|262|S NOP14 NucleOlar Protein 810.0 0 0 0 0 0.7938503030399562 Q99207 0.061282161623239524 0.056006725877523415 0.18824711441993716 0.6799145936965942 44.2425933035301 40.0 0.0 no 1409 chrIV_190002 4396 essential YDL148C 565 - ATCATCTTCATTGAATCGTT D|195|H D|195|N D|194|H D|194|N NOP14 NucleOlar Protein 810.0 0 0 0 0 0.5082138522057404 Q99207 0.017275422811508182 0.04070330783724785 0.139741450548172 0.4728562533855438 41.76529808704152 30.0 0.0 no 1410 chrIV_190343r 4401 essential YDL148C 221 + AACTGCTGATCGTATTGCTG T|75|S T|75|I A|76|G A|76|V NOP14 NucleOlar Protein 810.0 0 0 0 0 -1.1943172174870629 Q99207 1.0 0.20711541175842285 0.6271989345550537 0.2952343821525574 46.50655637762714 45.0 0.0 no 1411 chrIV_190425 4404 essential YDL148C 142 - CTCTTCTCTGATTTCAGCAA E|54|Q E|54|K E|53|Q E|53|K NOP14 NucleOlar Protein 810.0 0 0 0 0 1.007020312575134 Q99207 1.0 0.1342337131500244 0.07629856467247009 0.1969817876815796 47.40800697105527 40.0 0.0 no 1412 chrIV_190470 4405 essential YDL148C 97 - ATACTCCTTCGCTTGTCTTT E|38|D silent|GAG>GAA|E|38 E|38|Q E|38|K NOP14 NucleOlar Protein 810.0 0 0 0 0 0.2970802741090429 Q99207 0.18679164350032806 0.031696151942014694 0.02523247897624969 51.95483839559125 40.0 0.0 no 1413 chrIV_191034r 4406 essential YDL147W 113 - TCTTCTCCAACACTAACAGT K|44|N silent|AAG>AAA|K|44 E|43|D silent|GAG>GAA|E|43 RPN5 Regulatory Particle Non-ATPase 445.0 0 0 0 0 -1.084749211655764 Q12250 0.0039587169885635385 0.059072870761156075 46.02131917486497 40.0 1.0 no 1414 chrIV_191394 4411 essential YDL147W 470 + AGACATCTTGTGTGAGTTAC D|158|E silent|GAC>GAT|D|158 I|159|M silent|ATC>ATT|I|159 RPN5 Regulatory Particle Non-ATPase 445.0 0 0 0 0 0.5072689809212121 Q12250 0.5115104913711548 0.01370043121278286 44.26922060401864 40.0 1.0 no 1415 chrIV_191423r 4412 essential YDL147W 502 - AGACATTTCCATGGAGCCAT M|173|I M|173|I RPN5 Regulatory Particle Non-ATPase 445.0 0 0 0 0 -0.6197235618457079 Q12250 0.031119463965296745 0.031119463965296745 51.329667764757566 45.0 1.0 no 1416 chrIV_191504r 4415 essential YDL147W 583 - TCTTGAAAGCACCGTGGCTT R|201|T R|201|K RPN5 Regulatory Particle Non-ATPase 445.0 0 1 0 0 0.4854067249422447 Q12250 0.009943561628460884 0.8790428042411804 51.33925091119153 50.0 1.0 no 1417 chrIV_191505r 4416 essential YDL147W 584 - TTCTTGAAAGCACCGTGGCT R|201|T R|201|K RPN5 Regulatory Particle Non-ATPase 445.0 0 1 0 0 -1.195868025804911 Q12250 0.009943561628460884 0.8790428042411804 51.33925091119158 50.0 1.0 no 1418 chrIV_191554r 4417 essential YDL147W 633 - AGCTTCAATGACTCGTATTT K|217|N silent|AAG>AAA|K|217 L|216|F silent|TTG>TTA|L|216 RPN5 Regulatory Particle Non-ATPase 445.0 0 0 0 0 0.8996346967575635 Q12250 0.0034452294930815697 0.00895753689110279 43.954153082936045 35.0 1.0 no 1419 chrIV_191625r 4419 essential YDL147W 704 - GCAGATACTGCGCAACTTCT silent|CTG>CTC|L|241 silent|CTG>CTA|L|241 RPN5 Regulatory Particle Non-ATPase 445.0 0 0 0 0 -0.6511238867662157 Q12250 50.71181393680779 50.0 1.0 no 1420 chrIV_191722 4420 essential YDL147W 798 + TTCTTAGTCCTTTCACCTTA F|267|L silent|TTC>TTT|F|267 RPN5 Regulatory Particle Non-ATPase 445.0 0 0 0 0 1.2409190534089904 Q12250 0.02072437666356564 50.25825591895227 35.0 1.0 no 1421 chrIV_191737r 4422 essential YDL147W 816 - TCATTTTGTAAATTGCCGTA D|279|H D|279|N RPN5 Regulatory Particle Non-ATPase 445.0 0 0 0 0 0.34958477841356383 Q12250 0.004592612385749817 0.07563050836324693 42.269547714522325 30.0 1.0 no 1422 chrIV_191808r 4423 essential YDL147W 887 - ACAATTTTACTAAAGATTCT L|302|F silent|TTG>TTA|L|302 RPN5 Regulatory Particle Non-ATPase 445.0 0 1 0 0 -0.4017812526848372 Q12250 0.6735562086105347 33.09372683950954 20.0 1.0 no 1423 chrIV_195549 4429 essential YDL145C 2608 - ATCTTCGTCACCCAAATCCC D|876|H D|876|N E|875|Q E|875|K COP1 COat Protein 1201.0 0 0 0 0 -3.5926604752065865 P53622 0.8588730096817017 0.988381028175354 0.9043909907341005 0.9806360006332396 0.03628835082054138 0.09322454780340196 0.2641145586967468 0.29635798931121826 53.71397273581397 50.0 0.0 yes 1424 chrIV_195864 4436 essential YDL145C 2293 - ATCTCCGTTAGCCTTTGCTA D|771|H D|771|N G|770|A G|770|E COP1 COat Protein 1201.0 0 0 0 0 -0.8490380620373539 P53622 0.9220160245895386 0.9443740248680116 0.966946005821228 0.859483003616333 0.17846991121768951 0.07939224690198897 0.00995884370058775 0.054700449109077454 -0.01547999959439039 -0.2273799926042557 1.375599980354309 1.8915599584579468 55.35807118893217 45.0 0.0 no 1425 chrIV_196028 4439 essential YDL145C 2129 - CGTCACCTGTAACTAAATAC D|716|H D|716|N G|715|A G|715|D COP1 COat Protein 1201.0 0 0 0 0 -6.458454828863647 P53622 0.7815650105476379 0.9353979825973512 0.7056769728660583 0.5907639861106873 0.019443552941083908 1.0 0.0 0.0 3.5175199508666988 0.2385600060224533 3.5166800022125244 5.134580135345459 40.683916116005655 40.0 0.0 yes 1426 chrIV_196032 4440 essential YDL145C 2125 - ACCTGTAACTAAATACAGGA G|715|R G|715|S G|715|A G|715|D COP1 COat Protein 1201.0 0 0 0 0 -0.9162696911557964 P53622 0.5781090259552002 0.6638380289077759 0.7056769728660583 0.5907639861106873 0.0 0.0 0.0 0.0 3.6424601078033447 4.904560089111328 3.5166800022125244 5.134580135345459 39.62507490389851 35.0 0.0 no 1427 chrIV_196142r 4442 essential YDL145C 2012 + ACTGAATGATTCTAGTACTT L|672|V silent|CTG>TTG|L|672 COP1 COat Protein 1201.0 0 1 0 0 0.2772706934998327 P53622 0.9758639931678772 0.02215499989688396 1.6805599927902222 39.270913724692655 30.0 0.0 no 1428 chrIV_196190r 4443 essential YDL145C 1964 + AGCTTTGGAATACGGTAATT A|656|G A|656|V COP1 COat Protein 1201.0 0 0 0 0 -0.4515159115459694 P53622 0.8769879937171936 0.7689149975776672 0.0144911240786314 0.0044627003371715546 1.8986999988555908 4.1858201026916495 41.70394183099359 35.0 0.0 no 1429 chrIV_196205r 4445 essential YDL145C 1949 + TATCCGTTTTGATTTAGCTT I|651|M silent|ATC>ATT|I|651 R|652|G R|652|C COP1 COat Protein 1201.0 0 0 0 0 0.14669944819866865 P53622 0.9530439972877502 0.6741690039634705 0.6249070167541504 0.004023617133498192 0.0029936027713119984 0.00038470476283691823 -0.6240800023078918 2.403160095214844 1.7863999605178833 45.00161845154395 30.0 0.0 no 1430 chrIV_196361r 4449 essential YDL145C 1793 + TACAGAATATCGCTTCAAAA T|599|R T|599|I COP1 COat Protein 1201.0 0 0 0 0 -0.20125386057223127 P53622 0.9213179945945741 0.8819230198860168 0.0020210938528180122 0.002299800282344222 36.12391974588167 30.0 0.0 no 1431 chrIV_196489r 4451 essential YDL145C 1665 + TCACTATTGAACGGGGATAG L|557|V silent|CTA>TTA|L|557 S|556|* S|556|L COP1 COat Protein 1201.0 0 0 0 0 -1.1465637434167908 P53622 0.9434760212898254 1.000540018081665 0.04681537672877312 0.3578161895275116 42.83515359805108 45.0 0.0 no 1432 chrIV_196545 4452 essential YDL145C 1612 - TACACCAGTTTCATCCCAAG V|544|L V|544|I G|543|A G|543|D COP1 COat Protein 1201.0 0 0 0 0 -0.08251911813627028 P53622 0.9743090271949768 1.0179699659347534 0.9640139937400818 0.964347004890442 0.014981385320425034 0.1411600410938263 0.02706923522055149 0.06441592425107956 49.84998601344029 45.0 0.0 no 1433 chrIV_196957 4464 essential YDL145C 1200 - ACAGCTCCAACTGGTTGTTT V|407|L V|407|M A|406|P A|406|T COP1 COat Protein 1201.0 0 0 0 0 0.09646217470233676 P53622 1.0475499629974363 1.012310028076172 1.0764800310134888 1.1011899709701538 0.33220329880714417 0.11272046715021132 0.17903365194797516 0.5886604189872742 51.85199754555879 45.0 0.0 no 1434 chrIV_197242 4470 essential YDL145C 915 - GCACCAAATAGATTGATATG G|311|A G|311|D A|312|P A|312|T COP1 COat Protein 1201.0 0 0 0 0 -1.156578619659603 P53622 1.0005199909210205 0.8980540037155151 0.8602169752120972 0.958085000514984 1.0 0.0027690448332577944 0.00725916586816311 0.07657507807016373 3.727139949798584 2.3564000129699707 38.74857136748807 35.0 0.0 no 1435 chrIV_197245r 4471 essential YDL145C 909 + CATCCTCATATCAATCTATT P|305|A P|305|S P|305|R P|305|L COP1 COat Protein 1201.0 0 0 0 0 -1.2599280798884775 P53622 0.8970909714698792 0.8952000141143799 0.8547559976577759 0.8646739721298218 0.009394248016178608 0.00696587422862649 0.02247871272265911 0.004707168787717818 42.165971768558734 30.0 0.0 no 1436 chrIV_197469r 4473 essential YDL145C 685 + ACGACCGTCAAGTTAAATTA D|229|E silent|GAC>GAT|D|229 D|230|E silent|GAC>GAT|D|230 COP1 COat Protein 1201.0 0 0 0 0 0.4095415946439364 P53622 0.9499710202217102 0.8978829979896545 0.0 0.0 40.335937677081354 35.0 0.0 no 1437 chrIV_197465 4474 essential YDL145C 692 - TTCTCCATAATTTAACTTGA R|237|T R|237|K W|236|C W|236|* COP1 COat Protein 1201.0 0 0 0 0 -0.6434189784509573 P53622 0.95627099275589 0.9934380054473876 0.7476300001144409 0.0 0.0 0.0 38.66276645279078 25.0 0.0 no 1438 chrIV_197478 4475 essential YDL145C 679 - AACTTGACGGTCGTCACTGC V|233|L V|233|I COP1 COat Protein 1201.0 0 0 0 0 -1.0104303958179857 P53622 0.8569980263710022 0.91457200050354 0.15010912716388702 0.3506714105606079 50.83403714605049 55.00000000000001 0.0 no 1439 chrIV_197629 4483 essential YDL145C 528 - TCCTCAAATGAACTAGTACC E|182|D silent|GAG>GAA|E|182 E|183|Q E|183|K COP1 COat Protein 1201.0 0 1 0 0 -0.7229982307606166 P53622 1.0529400110244749 1.004330039024353 0.9752050042152404 0.6208304762840271 0.3833006322383881 0.6030940413475037 0.9003400206565857 42.91427782854846 40.0 0.0 no 1440 chrIV_197891r 4493 essential YDL145C 263 + ATACACCTTAACTGGGCATT Y|89|* silent|TAC>TAT|Y|89 T|90|S T|90|I COP1 COat Protein 1201.0 0 0 0 0 0.4200559066989323 P53622 0.962302029132843 0.9438390135765076 0.08141721785068512 0.0036226452793926 46.92327572094053 40.0 0.0 no 1441 chrIV_197962r 4495 essential YDL145C 192 + CAACCGATTTTTGTTTCGGC P|66|A P|66|S P|66|R P|66|L COP1 COat Protein 1201.0 0 0 0 0 0.35784560733208737 P53622 0.8930429816246033 0.8829789757728577 0.7657849788665771 0.7829430103302002 0.07016493380069733 0.017389802262187004 0.003187269438058138 0.0033929841592907906 47.86213827944681 45.0 0.0 no 1442 chrIV_198016r 4498 essential YDL145C 138 + CACAGATTTGAAGACCACGA H|47|Q silent|CAC>CAT|H|47 COP1 COat Protein 1201.0 0 0 0 0 1.1581258285469536 P53622 0.9486590027809144 0.023128781467676163 -0.20943999290466309 43.610743557960795 45.0 0.0 no 1443 chrIV_198085 4501 essential YDL145C 72 - AACAAAGCCACCAAAACCCA L|30|F silent|TTG>TTA|L|30 COP1 COat Protein 1201.0 0 0 0 0 -0.2303421885100132 P53622 0.8539689779281616 0.010771870613098145 0.37474000453948975 45.55542072387146 45.0 0.0 no 1444 chrIV_198101r 4505 essential YDL145C 53 + CTTCCACCCCTCCAGACCTT F|19|L silent|TTC>TTT|F|19 H|20|D H|20|Y COP1 COat Protein 1201.0 0 0 0 0 0.674425078196636 P53622 0.9457740187644958 0.8657360076904297 0.8535720109939575 0.0 0.0 0.0 63.97181024627275 60.0 0.0 no 1445 chrIV_198130r 4509 essential YDL145C 24 + TCAAAGTCCACTAGGGCCAA S|9|* S|9|L COP1 COat Protein 1201.0 0 1 0 0 -5.1780255402370825 P53622 0.8715919852256775 0.007126261480152606 50.804102853758074 50.0 0.0 yes 1446 chrIV_198131r 4510 essential YDL145C 23 + ATCAAAGTCCACTAGGGCCA S|9|* S|9|L COP1 COat Protein 1201.0 0 1 0 0 -4.749170478104363 P53622 0.8715919852256775 0.007126261480152606 52.44644357641312 50.0 0.0 yes 1447 chrIV_200116r 4516 essential YDL143W 123 - ATCATCTTGTCCATACCCTT M|47|I M|47|I K|46|N silent|AAG>AAA|K|46 CCT4 Chaperonin Containing TCP-1 528.0 0 1 0 0 -2.8518680999182773 P39078 0.9553959965705872 0.9553959965705872 0.9355990290641784 0.04478127136826515 0.04478127136826515 0.00345303094945848 0.5631999969482422 0.5631999969482422 1.5820000171661377 53.04267127366245 40.0 1.0 yes 1448 chrIV_200117r 4517 essential YDL143W 124 - AATCATCTTGTCCATACCCT M|47|I M|47|I K|46|N silent|AAG>AAA|K|46 CCT4 Chaperonin Containing TCP-1 528.0 0 1 0 0 -0.9068205900575784 P39078 0.9553959965705872 0.9553959965705872 0.9355990290641784 0.04478127136826515 0.04478127136826515 0.00345303094945848 0.5631999969482422 0.5631999969482422 1.5820000171661377 51.039978959411876 40.0 1.0 no 1449 chrIV_200178 4518 essential YDL143W 182 + CCACACCATTCTAAAACAGA H|62|Q silent|CAC>CAT|H|62 H|62|D H|62|Y CCT4 Chaperonin Containing TCP-1 528.0 0 1 0 0 1.4764704721513668 P39078 0.9588389992713928 0.9473130106925964 0.9489949941635132 0.020802764222025868 0.08005641400814056 0.01070316880941391 0.21739999949932096 1.7111999988555908 -2.0002000331878658 42.89015189261869 40.0 1.0 no 1450 chrIV_200287 4524 essential YDL143W 291 + ATCTTGACCGGAGCTCTATT I|98|M silent|ATC>ATT|I|98 CCT4 Chaperonin Containing TCP-1 528.0 0 0 0 0 -1.7670306901200326 P39078 0.9598389863967896 0.007559475954622029 1.416800022125244 50.690428651822 45.0 1.0 no 1451 chrIV_200337 4529 essential YDL143W 341 + CATCCATCCAACCATCATTG I|115|M silent|ATC>ATT|I|115 H|116|D H|116|Y CCT4 Chaperonin Containing TCP-1 528.0 0 0 0 0 -0.13043682375786653 P39078 0.9598389863967896 0.9473130106925964 0.9489949941635132 0.003588654333725572 0.01764433085918426 0.003753948956727981 0.26840001344680786 -1.8184000253677368 0.5932000279426575 -0.09780000150203703 -0.15399999916553495 1.4420000314712524 49.14751481515333 45.0 1.0 no 1452 chrIV_200484 4532 essential YDL143W 488 + GTCTCAATACTCTTCGTTTT S|164|C S|164|F Q|165|E Q|165|* CCT4 Chaperonin Containing TCP-1 528.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.4862130971821351 P39078 0.945252001285553 0.9294660091400146 0.9590039849281312 0.0257168747484684 0.07714657485485077 0.3665028512477875 0.6200000047683716 0.2313999980688095 0.2150000035762787 45.68443899714482 35.0 1.0 no 1453 chrIV_200525r 4534 essential YDL143W 532 - TTCATCAGATATCTTCAATA E|184|Q E|184|K D|183|H D|183|N CCT4 Chaperonin Containing TCP-1 528.0 0 1 0 0 -1.1471421697173734 P39078 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.6090999841690063 0.9621345996856691 0.01943591982126236 0.27755582332611084 -0.04399999976158142 -0.3792000114917755 0.06260000169277191 0.07720000296831131 37.7989231725004 25.0 1.0 no 1454 chrIV_200565r 4536 essential YDL143W 572 - TGACCAGTCTGATATCGTTC V|197|L V|197|I silent|CTG>CTC|L|196 silent|CTG>CTA|L|196 CCT4 Chaperonin Containing TCP-1 528.0 0 0 0 0 -1.6254153742606503 P39078 0.9539830088615416 0.9574310183525084 0.05282153934240341 0.6628463268280029 -0.6462000012397766 -1.1926000118255615 48.187899611691314 45.0 1.0 no 1455 chrIV_200603r 4537 essential YDL143W 610 - TATCATTTCTGTGTCATCAA M|209|I M|209|I CCT4 Chaperonin Containing TCP-1 528.0 0 0 0 0 -1.265408629416904 P39078 0.9553959965705872 0.9553959965705872 0.02014726959168911 0.02014726959168911 1.2079999446868896 1.2079999446868896 0.6880000233650208 0.6880000233650208 42.23799044374135 30.0 1.0 no 1456 chrIV_200661 4539 essential YDL143W 665 + TGCTGGTGGTCCGACAAGAA A|223|G A|223|V CCT4 Chaperonin Containing TCP-1 528.0 0 0 0 0 0.06872334729959045 P39078 0.9484469890594482 0.9504740238189696 0.3306591510772705 0.5166293978691101 0.9480000138282776 0.1858000010251999 51.46629714412915 55.00000000000001 1.0 no 1457 chrIV_201032r 4543 essential YDL143W 1039 - GATCTCCTCAACTAAATCAG E|352|D silent|GAG>GAA|E|352 E|352|Q E|352|K CCT4 Chaperonin Containing TCP-1 528.0 0 0 0 0 -4.649153390383108 P39078 0.94931298494339 0.956179976463318 0.9475290179252625 0.08178142458200455 0.18178823590278625 0.02076597884297371 -0.01779999956488609 -0.8023999929428101 -0.5424000024795532 41.73339878461121 40.0 1.0 yes 1458 chrIV_201067 4544 essential YDL143W 1071 + TCCAAGATAGTTAGAGTAAC silent|TCC>TCG|S|358 silent|TCC>TCT|S|358 S|358|C S|358|F CCT4 Chaperonin Containing TCP-1 528.0 0 0 0 0 -0.35136524635157795 P39078 0.945252001285553 0.9294660091400146 0.048923760652542114 0.05727991089224816 -0.7925999760627747 -0.9240000247955322 38.916714770430076 35.0 1.0 no 1459 chrIV_201068r 4545 essential YDL143W 1075 - ACCAGTTACTCTAACTATCT G|365|R G|365|S G|365|A G|365|D CCT4 Chaperonin Containing TCP-1 528.0 0 0 0 0 -0.30254945047107146 P39078 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.09871605783700944 0.15462584793567655 0.14287878572940824 0.05913509801030159 3.3194000720977783 4.042600154876709 3.0394001007080083 3.1161999702453613 44.630641861549975 35.0 1.0 no 1460 chrIV_203261 4556 essential YDL141W 222 + AAACATTTTGTTAGCAAACA H|76|D H|76|Y BPL1 Biotin:apoProtein Ligase 690.0 0 0 0 0 0.1877431914576233 P48445 0.9473130106925964 0.9489949941635132 0.5385834574699402 0.04744462668895722 35.344330012889365 25.0 1.0 no 1461 chrIV_203354r 4560 essential YDL141W 318 - CTTCCTGATACTTCCATTGT G|112|A G|112|E G|112|R G|112|R BPL1 Biotin:apoProtein Ligase 690.0 0 0 0 0 0.5567901474975236 P48445 0.9499930143356324 0.9438679814338684 0.941340982913971 0.941340982913971 0.0 0.0 0.0 0.0 50.17492187284961 40.0 1.0 no 1462 chrIV_203405 4563 essential YDL141W 366 + AGCAGAGGACCTGCGTACAA S|123|R silent|AGC>AGT|S|123 BPL1 Biotin:apoProtein Ligase 690.0 0 0 0 0 0.08782041047362515 P48445 0.9417110085487366 0.03522416204214096 52.162107568848846 55.00000000000001 1.0 no 1463 chrIV_203414r 4564 essential YDL141W 378 - TACTGAAATCCATTGTACGC Q|132|H silent|CAG>CAA|Q|132 BPL1 Biotin:apoProtein Ligase 690.0 0 0 0 0 0.536772449583956 P48445 0.9570760130882264 0.1375151127576828 42.89893942943246 40.0 1.0 no 1464 chrIV_203588 4567 essential YDL141W 549 + CCTTCTTCTGACTCAGGAAA P|184|R P|184|L S|185|C S|185|F BPL1 Biotin:apoProtein Ligase 690.0 0 1 0 0 -1.0950536025964153 P48445 0.9432820081710817 0.9430609941482544 0.945252001285553 0.9294660091400146 0.17458218336105347 0.10582214593887328 0.15536421537399292 0.4341951310634613 47.40523612874614 45.0 1.0 no 1465 chrIV_203623r 4569 essential YDL141W 587 - TACATAGCACTACAGCAGCT C|202|S C|202|Y BPL1 Biotin:apoProtein Ligase 690.0 0 0 0 0 0.5673545259568384 P48445 0.9421560168266296 0.9290120005607604 0.4337611198425293 0.13598521053791046 49.09861562353848 45.0 1.0 no 1466 chrIV_203739r 4575 essential YDL141W 703 - TGCTTTCAGGTTTTCCACAA A|241|P A|241|T silent|CTG>CTC|L|239 silent|CTG>CTA|L|239 BPL1 Biotin:apoProtein Ligase 690.0 0 0 0 0 -0.2373606721996557 P48445 0.9573720097541808 0.9523990154266356 0.25368285179138184 0.5672328472137451 49.79942966613015 40.0 1.0 no 1467 chrIV_203752r 4576 essential YDL141W 716 - TCATGATTTCCTGTGCTTTC M|245|I M|245|I BPL1 Biotin:apoProtein Ligase 690.0 0 0 0 0 -0.02128018768686125 P48445 0.9553959965705872 0.9553959965705872 0.18321342766284945 0.18321342766284945 49.71961529560178 40.0 1.0 no 1468 chrIV_203871 4578 essential YDL141W 832 + TGGCTAGTGCACCTAATAAG A|279|G A|279|V BPL1 Biotin:apoProtein Ligase 690.0 0 0 0 0 0.12499952067636805 P48445 0.9484469890594482 0.9504740238189696 0.11641058325767514 0.3225627541542053 46.07417459642392 45.0 1.0 no 1469 chrIV_203992r 4579 essential YDL141W 956 - CTCTATAGCCTCTATAAAAT R|325|T R|325|K BPL1 Biotin:apoProtein Ligase 690.0 0 0 0 0 0.10734147935081854 P48445 0.932735025882721 0.955805003643036 0.5815219283103943 0.9155513644218444 39.39489230023406 30.0 1.0 no 1470 chrIV_203984 4580 essential YDL141W 945 + GACTCTTTCCAATTTTATAG D|316|E silent|GAC>GAT|D|316 S|317|C S|317|F BPL1 Biotin:apoProtein Ligase 690.0 0 0 0 0 0.51304004117059 P48445 0.9532920122146606 0.945252001285553 0.9294660091400146 0.0 0.008912836201488972 0.005340654868632555 40.29783288372312 30.0 1.0 no 1471 chrIV_204551 4591 essential YDL141W 1512 + AACTTGAAATTGGTTAACAC N|505|K silent|AAC>AAT|N|505 BPL1 Biotin:apoProtein Ligase 690.0 0 0 0 0 0.2556405165697445 P48445 0.9439849853515624 1.0 34.69445483197171 30.0 1.0 no 1472 chrIV_206660 4594 essential YDL140C 3882 - TCCTTAACGTATTCACCAGT K|1300|N silent|AAG>AAA|K|1300 E|1301|Q E|1301|K RPO21 RNA POlymerase 1733.0 0 0 0 0 0.2748454767920629 P04050 0.28117501735687256 0.5981892347335815 0.9268186092376708 -0.4081999957561493 48.38615538454571 40.0 0.0 no 1473 chrIV_207061 4599 essential YDL140C 3481 - TTCATCTTCTGGAATAACTG E|1167|Q E|1167|K D|1166|H D|1166|N RPO21 RNA POlymerase 1733.0 0 0 0 0 0.27052959244019564 P04050 0.9366211891174316 0.5537853240966797 0.0 0.0 39.900874505016304 35.0 0.0 no 1474 chrIV_207163 4600 essential YDL140C 3379 - CAACTTCGCTTGTTCTTGAT K|1132|N silent|AAG>AAA|K|1132 silent|GCG>GCC|A|1131 silent|GCG>GCA|A|1131 RPO21 RNA POlymerase 1733.0 1 Series([], Name: modification, dtype: object) 0 0 0 -1.7447846708789434 P04050 0.03686110675334929 1.823199987411499 46.53210278887104 40.0 0.0 no 1475 chrIV_207196 4601 essential YDL140C 3346 - AGGCTCTAAGTATACAGTCA E|1121|D silent|GAG>GAA|E|1121 E|1121|Q E|1121|K RPO21 RNA POlymerase 1733.0 0 0 0 0 -1.7006794323459105 P04050 0.3916193246841431 0.4708665013313294 1.0 46.1277875100941 40.0 0.0 no 1476 chrIV_207245 4605 essential YDL140C 3297 - TTCAAAATTTCCTTTAAACG L|1105|F silent|TTG>TTA|L|1105 RPO21 RNA POlymerase 1733.0 0 1 0 0 0.28858008467719465 P04050 0.010182486847043036 34.39371414269198 25.0 0.0 no 1477 chrIV_207255r 4607 essential YDL140C 3284 + TTCTGGTGTCCCCCGTTTAA S|1096|C S|1096|F RPO21 RNA POlymerase 1733.0 0 1 0 0 0.2601521969209123 P04050 0.002520210575312376 0.01176499854773283 57.88943340632864 50.0 0.0 no 1478 chrIV_207344r 4612 essential YDL140C 3195 + GTTCTAGCAGCCCAATCCAT L|1067|V silent|CTA>TTA|L|1067 RPO21 RNA POlymerase 1733.0 0 0 0 0 -0.06986375484577961 P04050 0.39978066086769104 56.634202276830024 50.0 0.0 no 1479 chrIV_207363 4613 essential YDL140C 3179 - GAACACCAACCATTTCACCA V|1066|L V|1066|I G|1065|A G|1065|D RPO21 RNA POlymerase 1733.0 0 0 0 0 -0.038184268224417006 P04050 0.06404032558202744 0.08515522629022597 0.0 0.0 48.37757936816155 45.0 0.0 no 1480 chrIV_207596r 4621 essential YDL140C 2943 + ACAATCAAAGACATCGTTCT T|982|R T|982|I I|983|M silent|ATC>ATT|I|983 RPO21 RNA POlymerase 1733.0 0 0 0 0 -0.3358927808163327 P04050 0.5640971064567566 0.1730319857597351 0.03508089855313301 39.78007622084596 35.0 0.0 no 1481 chrIV_207874 4625 essential YDL140C 2668 - TCTCTTTTCAAAAGCTGCAT K|895|N silent|AAG>AAA|K|895 R|896|T R|896|K RPO21 RNA POlymerase 1733.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.5370457116016742 P04050 0.10552547872066498 0.375213086605072 1.0 43.828961447681706 35.0 0.0 no 1482 chrIV_207981r 4628 essential YDL140C 2558 + TAACACCACAAGAAACTCAT N|854|K silent|AAC>AAT|N|854 T|855|S T|855|I RPO21 RNA POlymerase 1733.0 0 0 0 0 0.7285693729015916 P04050 0.02989926002919674 0.05403875932097435 0.0014064073329791427 -0.8916000127792358 -1.7242000102996826 38.24162580310161 35.0 0.0 no 1483 chrIV_208095 4630 essential YDL140C 2447 - CTTCACGACCACCCATTGCA E|822|Q E|822|K R|821|P R|821|H RPO21 RNA POlymerase 1733.0 0 0 0 0 -1.3973883406148744 P04050 0.005692058242857456 0.0354689322412014 0.0 0.0 1.2117999792099 0.5297999978065491 55.7803165648121 55.00000000000001 0.0 no 1484 chrIV_208160 4631 essential YDL140C 2382 - TCAACAAAACCTTTAGACTC E|801|Q E|801|K V|800|L V|800|I RPO21 RNA POlymerase 1733.0 0 1 0 0 -0.1947853749941736 P04050 0.037153232842683785 0.10826899856328964 0.008209498599171637 0.0350942462682724 38.23228241220062 35.0 0.0 no 1485 chrIV_208162 4633 essential YDL140C 2380 - AACAAAACCTTTAGACTCTG V|800|L V|800|I RPO21 RNA POlymerase 1733.0 0 1 0 0 0.3254945062293472 P04050 0.008209498599171637 0.0350942462682724 37.873845883465094 35.0 0.0 no 1486 chrIV_208377 4636 essential YDL140C 2165 - CCTTATCTCTTGCTTCATTT K|728|N silent|AAG>AAA|K|728 D|727|H D|727|N RPO21 RNA POlymerase 1733.0 0 0 0 0 0.2060903877719905 P04050 0.4131537973880768 0.0023567681200802326 0.04589780420064926 5.3368000984191895 1.4869999885559082 49.26604892367146 35.0 0.0 no 1487 chrIV_208416r 4638 essential YDL140C 2123 + GACTCTCCGTGAGTCTTTTG T|709|S T|709|I L|710|V L|710|F RPO21 RNA POlymerase 1733.0 0 1 0 0 -1.0267671065740842 P04050 0.21785810589790344 0.0038201727438718076 0.4336026906967163 0.028781192377209663 -1.5468000173568726 0.10499999672174454 0.9954000115394592 0.23240000009536746 51.85724795500994 50.0 0.0 no 1488 chrIV_208442r 4639 essential YDL140C 2097 + AACTTATTGACTGCTAAACA N|700|K silent|AAC>AAT|N|700 RPO21 RNA POlymerase 1733.0 0 1 0 0 -0.7975133228782629 P04050 0.15928824245929718 1.2364000082015991 37.47301090452135 30.0 0.0 no 1489 chrIV_208449 4640 essential YDL140C 2093 - TAGCAGTCAATAAGTTTGCC A|704|P A|704|T RPO21 RNA POlymerase 1733.0 0 1 0 0 0.17934116259541172 P04050 0.9306015968322754 0.9500013589859008 -0.6715999841690063 1.4081000089645386 45.60837386619937 40.0 0.0 no 1490 chrIV_208520 4644 essential YDL140C 2022 - TCTGTAATTTCCCTCATTGT E|681|Q E|681|K RPO21 RNA POlymerase 1733.0 0 0 0 0 0.4029991774159037 P04050 0.28740382194519043 0.4017733037471771 48.6977336137794 35.0 0.0 no 1491 chrIV_208594r 4646 essential YDL140C 1945 + TACAGAAAGTTGTTAACTTT Q|650|E Q|650|* RPO21 RNA POlymerase 1733.0 0 0 0 0 -1.4902938468950968 P04050 0.007490787655115127 35.06503362746128 25.0 0.0 no 1492 chrIV_208625 4647 essential YDL140C 1917 - AACAACTTAGCACAAACTTG L|645|F silent|TTG>TTA|L|645 K|644|N silent|AAG>AAA|K|644 RPO21 RNA POlymerase 1733.0 0 0 0 0 0.4943108379182491 P04050 1.0 0.5067272782325745 36.88162178042745 35.0 0.0 no 1493 chrIV_208650r 4648 essential YDL140C 1889 + TCATGTTGTTACGAGAGAAA H|631|D H|631|Y RPO21 RNA POlymerase 1733.0 0 0 0 0 -0.2670152979197833 P04050 0.03840132057666778 0.0017079366371035574 39.034819689555256 35.0 0.0 no 1494 chrIV_208666 4649 essential YDL140C 1876 - AACATGAATTAAACCACCAT V|632|L V|632|I RPO21 RNA POlymerase 1733.0 0 0 0 0 0.7402308029133472 P04050 0.24234919250011444 1.0 38.00412489287129 30.0 0.0 no 1495 chrIV_208782r 4651 essential YDL140C 1757 + TCATTTACAACGTTTTGATG H|587|D H|587|Y RPO21 RNA POlymerase 1733.0 0 0 0 0 0.279149154964161 P04050 0.028135363012552258 0.01245680917054415 38.123145953212095 30.0 0.0 no 1496 chrIV_208822 4652 essential YDL140C 1720 - CACAGACAAGATTTGTTTAC V|580|L V|580|M L|578|F silent|TTG>TTA|L|578 RPO21 RNA POlymerase 1733.0 0 0 0 0 0.3298477686561585 P04050 1.0 0.3496009707450867 1.0 38.49434590588317 35.0 0.0 no 1497 chrIV_208998r 4658 essential YDL140C 1541 + ACAATCTAACAAACCTTGTA Q|515|E Q|515|* S|516|C S|516|F RPO21 RNA POlymerase 1733.0 0 0 0 0 0.526481500593146 P04050 0.0 0.05052721127867699 0.022110098972916603 37.80527746755155 30.0 0.0 no 1498 chrIV_209000 4659 essential YDL140C 1542 - ATACAAGGTTTGTTAGATTG C|520|S C|520|Y RPO21 RNA POlymerase 1733.0 0 0 0 0 -0.021534101375446767 P04050 0.0022077588364481926 0.0010132106253877282 37.93555103193933 30.0 0.0 no 1499 chrIV_209076r 4662 essential YDL140C 1463 + TCTTCACGTTCCTCAGTCTG L|489|V L|489|F H|490|D H|490|Y RPO21 RNA POlymerase 1733.0 0 1 0 0 -0.8297219983348161 P04050 0.010552024468779564 0.01014796644449234 0.00700144749134779 0.003196379402652383 54.08857406457105 50.0 0.0 no 1500 chrIV_209111r 4664 essential YDL140C 1428 + CCATACAATGCCGATTTCGA P|477|R P|477|L Y|478|* silent|TAC>TAT|Y|478 RPO21 RNA POlymerase 1733.0 0 1 0 0 -1.899083085787588 P04050 0.0 0.0 47.54304956383544 45.0 0.0 no 1501 chrIV_209341 4666 essential YDL140C 1201 - ACGAATGACGTATTTGGCAC R|407|P R|407|H RPO21 RNA POlymerase 1733.0 0 0 0 0 -0.30655697933248083 P04050 0.002115546725690365 0.0023924848064780235 0.7275999784469604 0.5451999902725221 43.822956849988145 45.0 0.0 no 1502 chrIV_209424r 4669 essential YDL140C 1115 + GACTTTAACATACCCAGAAG T|373|S T|373|I RPO21 RNA POlymerase 1733.0 0 1 0 0 1.3800266962528709 P04050 0.21799029409885406 0.16835616528987885 41.79193789027505 40.0 0.0 no 1503 chrIV_209471 4670 essential YDL140C 1071 - ACTTGGTCTAATTCCAAATT V|364|L V|364|I RPO21 RNA POlymerase 1733.0 0 1 0 0 -0.6172290306851123 P04050 0.3192492723464966 0.024998689070343968 41.11112416765457 30.0 0.0 no 1504 chrIV_209571r 4673 essential YDL140C 968 + ATCTATTCGTGCTCGTTTGA S|324|C S|324|F RPO21 RNA POlymerase 1733.0 0 0 0 0 0.6006974806989269 P04050 0.0036680209450423717 0.0015590738039463758 48.491473344266815 40.0 0.0 no 1505 chrIV_209788 4679 essential YDL140C 754 - ACCTCTTTGAGATTCATTGA G|258|R G|258|S G|258|A G|258|D RPO21 RNA POlymerase 1733.0 0 0 0 0 -1.0046053887972601 P04050 0.03863710165023804 0.7789440751075745 0.30566129088401794 0.15889251232147214 9.335800170898438 2.9193999767303467 1.5225000381469729 4.724200248718262 45.16713245348723 35.0 0.0 no 1506 chrIV_209946r 4682 essential YDL140C 593 + ACTAAGAGTTTTAAGTACGG L|199|V silent|CTA>TTA|L|199 RPO21 RNA POlymerase 1733.0 0 0 0 0 -0.9108479603782804 P04050 0.08529723435640335 38.14032060980969 35.0 0.0 no 1507 chrIV_209951 4683 essential YDL140C 591 - GTACTTAAAACTCTTAGTTC S|203|T S|203|N RPO21 RNA POlymerase 1733.0 0 0 0 0 -0.2788921063858372 P04050 1.0 0.18353553116321564 36.9387930347155 30.0 0.0 no 1508 chrIV_210033r 4685 essential YDL140C 506 + TACACAGCCTACAATTCGTA T|170|R T|170|I Q|171|E Q|171|* RPO21 RNA POlymerase 1733.0 0 1 0 0 -0.7957782633477 P04050 0.4114016592502594 0.4168286919593811 0.013432755134999752 45.657562602295855 40.0 0.0 no 1509 chrIV_210069r 4689 essential YDL140C 470 + TCCTACTCAGCTCGTATCAA P|158|R P|158|L P|158|A P|158|S RPO21 RNA POlymerase 1733.0 0 0 0 0 0.022424007528995062 P04050 0.5226770639419556 0.31149739027023315 0.7299289703369141 0.7138926386833191 0.9897400140762328 0.41617000102996826 0.9245699644088744 0.8961000442504883 50.488439451906515 45.0 0.0 no 1510 chrIV_210281r 4691 essential YDL140C 258 + GCAAAACCTGTATTTCATGT A|87|G A|87|V P|89|A P|89|S RPO21 RNA POlymerase 1733.0 0 0 0 0 0.5831613842178576 P04050 0.13655750453472135 0.1997777670621872 0.0 0.0 43.076766136319684 35.0 0.0 no 1511 chrIV_210317r 4693 essential YDL140C 222 + AACGAATGTCCTGGTCATTT N|75|K silent|AAC>AAT|N|75 RPO21 RNA POlymerase 1733.0 0 1 0 0 -0.21500509111789365 P04050 1.0 0.1635066717863083 45.907429199999676 40.0 0.0 no 1512 chrIV_210512 4698 essential YDL140C 30 - ACCTCTTTTACTGTACGGAG E|16|D silent|GAG>GAA|E|16 V|17|L V|17|I RPO21 RNA POlymerase 1733.0 0 0 0 0 0.4698784623722132 P04050 0.3997438251972199 0.13373713195323944 0.7764922976493835 1.7899856567382812 47.971563055959045 45.0 0.0 no 1513 chrIV_211772 4701 essential YDL139C 255 - ACTTCATCATCGGTTAGTTT V|92|L V|92|I E|91|Q E|91|K SCM3 Suppressor of Chromosome Missegregation 223.0 0 0 0 0 0.9460182530071616 Q12334 0.9539830088615416 0.9574310183525084 0.956179976463318 0.9475290179252625 0.04470901936292648 0.3096351623535156 0.2855924069881439 0.022152433171868324 46.402053763354786 35.0 0.0 no 1514 chrIV_211773 4702 essential YDL139C 254 - CTTCATCATCGGTTAGTTTA E|91|Q E|91|K D|90|H D|90|N SCM3 Suppressor of Chromosome Missegregation 223.0 0 0 0 0 0.028737480506630938 Q12334 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.2855924069881439 0.022152433171868324 0.013817744329571724 0.027863554656505585 45.33288124814726 35.0 0.0 no 1515 chrIV_211809r 4703 essential YDL139C 215 + TCATGTGTATATAATGTCCA H|73|D H|73|Y SCM3 Suppressor of Chromosome Missegregation 223.0 0 0 0 0 0.37115404874788055 Q12334 0.9473130106925964 0.9489949941635132 0.15505044162273407 0.6706499457359314 41.943271793993404 30.0 0.0 no 1516 chrIV_211829 4704 essential YDL139C 198 - TGACCATTTCTTTCAGCAAT G|72|A G|72|D G|72|R G|72|S SCM3 Suppressor of Chromosome Missegregation 223.0 0 0 0 0 0.6927736675360585 Q12334 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.06782299280166626 0.10458091646432877 0.056073684245347984 0.06389843672513963 45.67337972418665 35.0 0.0 no 1517 chrIV_211969 4706 essential YDL139C 58 - CTCTTTCAATAGTCCTTTTA E|26|Q E|26|K L|24|F silent|TTG>TTA|L|24 SCM3 Suppressor of Chromosome Missegregation 223.0 0 0 0 0 0.4627617789682194 Q12334 0.956179976463318 0.9475290179252625 0.9587849974632264 0.4580525457859039 0.7739955186843872 0.0 -0.900600016117096 -0.8151999711990356 44.01653476699311 30.0 0.0 no 1518 chrIV_211989 4708 essential YDL139C 38 - AGGCACCATGGAGATTTTTC A|19|P A|19|T G|18|A G|18|D SCM3 Suppressor of Chromosome Missegregation 223.0 0 0 0 0 0.5602426629176311 Q12334 0.9573720097541808 0.9523990154266356 0.9499930143356324 0.9446240067481996 0.0 0.0 0.07413914054632187 0.04688679799437523 49.27120289868617 45.0 0.0 no 1519 chrIV_224341r 4710 essential YDL132W 40 - TGGCTCTATAAAGTTCCAAG E|19|D silent|GAG>GAA|E|19 E|19|Q E|19|K CDC53 Cell Division Cycle 815.0 0 0 0 0 -0.930687651119848 Q12018 0.10176083445549013 0.5969340801239014 0.232345387339592 43.280698114396564 40.0 1.0 no 1520 chrIV_224343 4711 essential YDL132W 39 + ACTTGGAACTTTATAGAGCC T|14|S T|14|I CDC53 Cell Division Cycle 815.0 0 0 0 0 -0.4971464565819014 Q12018 0.18520542979240415 0.006532601080834866 44.33869740126528 40.0 1.0 no 1521 chrIV_224360 4712 essential YDL132W 56 + GCCAGGAATTAACCAAATAC P|20|R P|20|L P|20|A P|20|S CDC53 Cell Division Cycle 815.0 0 0 0 0 -0.9054741370664118 Q12018 0.10586632043123244 0.06489486247301103 0.2596854567527771 0.2438653260469437 41.21342296477872 40.0 1.0 no 1522 chrIV_224525 4718 essential YDL132W 221 + AACTGGCCAATCAACAATTT T|75|S T|75|I silent|GGC>GGG|G|76 silent|GGC>GGT|G|76 CDC53 Cell Division Cycle 815.0 0 1 0 0 -0.003709507310620753 Q12018 0.8102555274963379 0.1824997216463089 41.49412124270896 35.0 1.0 no 1523 chrIV_224764 4720 essential YDL132W 460 + ACACCTTGTGCTTGATGACA T|155|S T|155|I N|154|K silent|AAC>AAT|N|154 CDC53 Cell Division Cycle 815.0 0 0 0 0 -0.2288703566689597 Q12018 0.1755874752998352 0.006443289574235678 0.3328970372676849 49.76370506408944 45.0 1.0 no 1524 chrIV_224912 4724 essential YDL132W 608 + TGCACTAGGTATCGATCCAC A|204|G A|204|V L|205|V silent|CTA>TTA|L|205 CDC53 Cell Division Cycle 815.0 0 0 0 0 -0.3575964916151053 Q12018 0.3276691436767578 0.5113683342933655 0.0 50.36480302689733 50.0 1.0 no 1525 chrIV_224928r 4725 essential YDL132W 627 - TTCAACTTTTTCAAATCCTG L|215|F silent|TTG>TTA|L|215 K|214|N silent|AAG>AAA|K|214 CDC53 Cell Division Cycle 815.0 0 0 0 0 -0.01788572069999636 Q12018 0.09824154525995256 0.011647969484329224 39.64344144530521 30.0 1.0 no 1526 chrIV_225125 4728 essential YDL132W 821 + TACAAAAAAACCACTATCCA T|275|R T|275|I CDC53 Cell Division Cycle 815.0 0 0 0 0 0.218053702876343 Q12018 0.005890653003007174 0.006502514239400625 36.256421594980786 30.0 1.0 no 1527 chrIV_225595r 4735 essential YDL132W 1294 - CATCTCGGAAGTCTTCGAGG E|437|D silent|GAG>GAA|E|437 E|437|Q E|437|K CDC53 Cell Division Cycle 815.0 0 0 0 0 -0.8014808415553241 Q12018 0.32324716448783875 0.16901211440563202 0.032877743244171136 49.14977677986985 55.00000000000001 1.0 no 1528 chrIV_225655r 4738 essential YDL132W 1354 - GTCACTTGCCACTTCAGGTT D|458|H D|458|N S|457|T S|457|N CDC53 Cell Division Cycle 815.0 0 0 0 0 0.3409033439474173 Q12018 0.02526522055268288 0.10996221750974657 0.4458786249160767 0.35762667655944824 56.29342307812345 50.0 1.0 no 1529 chrIV_225660r 4739 essential YDL132W 1359 - GACATGTCACTTGCCACTTC M|459|I M|459|I CDC53 Cell Division Cycle 815.0 0 0 0 0 0.5504346809496028 Q12018 0.22729386389255524 0.22729386389255524 52.138247916383364 50.0 1.0 no 1530 chrIV_225996r 4742 essential YDL132W 1695 - TCAACTTCTTGGTATGAAAA E|572|Q E|572|K V|571|L V|571|I CDC53 Cell Division Cycle 815.0 0 0 0 0 -0.1449644499776621 Q12018 0.5824213624000549 0.9161663651466371 0.6195583343505859 0.381614625453949 36.939368503744674 30.0 1.0 no 1531 chrIV_226113r 4745 essential YDL132W 1812 - TTCAATTCGCCACGACATAA L|610|F silent|TTG>TTA|L|610 CDC53 Cell Division Cycle 815.0 0 0 0 0 0.4121607190931773 Q12018 0.049133241176605225 44.160154859398354 40.0 1.0 no 1532 chrIV_236847 4747 essential YDL126C 1798 - AGCACCACCAGCATCACCCA A|606|P A|606|T G|605|A G|605|D CDC48 Cell Division Cycle 835.0 0 0 0 0 -0.3112565297601982 P25694 0.019319260492920882 0.2139068692922592 0.6250448822975159 0.6894798874855042 1.5140000581741333 1.0740000009536743 61.36465781833323 60.0 0.0 no 1533 chrIV_236871 4748 essential YDL126C 1774 - ACCACCTCTTGCCTTGGCAA G|598|R G|598|S G|598|A G|598|D CDC48 Cell Division Cycle 835.0 0 1 0 0 -2.7297505308328804 P25694 0.2645909786224365 1.0 0.5094961524009705 0.2458746433258057 58.79806970428154 55.00000000000001 0.0 yes 1534 chrIV_236875r 4750 essential YDL126C 1767 + GACTCCATTGCCAAGGCAAG D|590|E silent|GAC>GAT|D|590 S|591|C S|591|F CDC48 Cell Division Cycle 835.0 0 1 0 0 0.06485905587482349 P25694 0.0 0.002932516857981682 0.0011448018485680225 51.98786633705914 55.00000000000001 0.0 no 1535 chrIV_236936 4752 essential YDL126C 1709 - TTGCCTTATCAAAAATATCA A|576|P A|576|T K|575|N silent|AAG>AAA|K|575 CDC48 Cell Division Cycle 835.0 0 1 0 0 -0.6311753382614895 P25694 0.0 0.0 0.003052120795473457 37.06701286112826 25.0 0.0 no 1536 chrIV_236939r 4753 essential YDL126C 1703 + CATCCGTGATATTTTTGATA I|569|M silent|ATC>ATT|I|569 R|570|G R|570|C CDC48 Cell Division Cycle 835.0 0 1 0 0 0.07304622244284659 P25694 0.004167981445789336 0.002765043638646602 0.0003895187692251056 0.7319999933242798 0.5640000104904175 41.5271398470644 30.0 0.0 no 1537 chrIV_237004r 4754 essential YDL126C 1638 + GCCAACTTTATCTCAGTCAA silent|GCC>GCG|A|547 silent|GCC>GCT|A|547 A|547|G A|547|V CDC48 Cell Division Cycle 835.0 0 0 0 1 -0.17172874910920888 P25694 0.012700852006673813 0.03743529692292213 47.247009761325614 40.0 0.0 no 1538 chrIV_237003 4755 essential YDL126C 1642 - ACCTTTGACTGAGATAAAGT G|554|R G|554|S G|554|A G|554|D CDC48 Cell Division Cycle 835.0 0 0 0 0 -2.002814938126969 P25694 0.0 0.0 0.0 0.0 40.863351308701965 35.0 0.0 no 1539 chrIV_237170 4759 essential YDL126C 1475 - ATTCCTCCTTGATTTCATCT E|498|Q E|498|K E|497|D silent|GAG>GAA|E|497 CDC48 Cell Division Cycle 835.0 0 0 0 0 -0.41309127383058186 P25694 0.1705746352672577 0.03175915777683258 0.1290791481733322 50.09792505552474 35.0 0.0 no 1540 chrIV_237232 4761 essential YDL126C 1413 - ACGGTTTCACGCAATGCAGA V|478|L V|478|I CDC48 Cell Division Cycle 835.0 0 0 0 0 0.9414403159256416 P25694 0.6151900291442871 0.3081501424312592 49.678935382103255 50.0 0.0 no 1541 chrIV_237265r 4762 essential YDL126C 1377 + GACAACTTCAGATTCGCATT D|460|E silent|GAC>GAT|D|460 N|461|K silent|AAC>AAT|N|461 CDC48 Cell Division Cycle 835.0 0 0 0 0 0.08511412803194625 P25694 0.7491253614425659 0.13975171744823456 44.46023654480132 40.0 0.0 no 1542 chrIV_237298r 4764 essential YDL126C 1344 + GCAGAGGTGCTCGATTCTTT A|449|G A|449|V CDC48 Cell Division Cycle 835.0 0 0 0 0 0.20036459125167647 P25694 0.13371479511260986 0.13863304257392886 53.39017088725125 50.0 0.0 no 1543 chrIV_237549 4773 essential YDL126C 1096 - TCTACCAAATCTTCTTAAAG R|372|T R|372|K G|371|A G|371|D CDC48 Cell Division Cycle 835.0 0 0 0 0 -2.1231642864318983 P25694 0.0 0.0 0.017112094908952713 0.003379997098818421 3.2999999523162837 0.07400000095367433 36.99167023584971 30.0 0.0 yes 1544 chrIV_237550 4774 essential YDL126C 1095 - CTACCAAATCTTCTTAAAGC G|371|A G|371|D G|371|R G|371|S CDC48 Cell Division Cycle 835.0 0 0 0 0 0.4655358662412489 P25694 0.017112094908952713 0.003379997098818421 0.002049407223239541 0.00875832699239254 39.568459140063794 35.0 0.0 no 1545 chrIV_237573 4775 essential YDL126C 1072 - ATCAATCGAATTTGGTCTAT D|364|H D|364|N silent|TCG>TCC|S|362 silent|TCG>TCA|S|362 CDC48 Cell Division Cycle 835.0 0 0 0 0 -0.5092054653682601 P25694 0.00160049251280725 0.006667392794042826 39.68347458798127 30.0 0.0 no 1546 chrIV_237747 4780 essential YDL126C 898 - GTTCTTTTCGGCTTCTTCAA K|305|N silent|AAG>AAA|K|305 CDC48 Cell Division Cycle 835.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.5132807643825306 P25694 0.07099318504333496 50.070797057699785 40.0 0.0 no 1547 chrIV_237800r 4782 essential YDL126C 842 + TCCAGAAGTCATGTCAAAAA P|282|R P|282|L P|282|A P|282|S CDC48 Cell Division Cycle 835.0 0 0 0 0 -3.887582699109245 P25694 0.0 0.0 0.0 0.0 39.03333620358933 35.0 0.0 yes 1548 chrIV_237858 4783 essential YDL126C 787 - AGCAACAGCTCTTGCCATCA A|269|P A|269|T V|268|L V|268|I CDC48 Cell Division Cycle 835.0 0 0 0 0 -0.4042803658584384 P25694 0.006051578558981419 0.0049806819297373295 0.19749344885349274 0.29800742864608765 54.326495399196006 50.0 0.0 no 1549 chrIV_238051 4788 essential YDL126C 594 - TCTTCATCTTCCCTGTTGAT E|205|Q E|205|K E|204|Q E|204|K CDC48 Cell Division Cycle 835.0 0 0 0 0 0.07377496291428894 P25694 0.07103138417005539 0.22053585946559906 0.29489243030548096 0.397819846868515 52.588570736503065 40.0 0.0 no 1550 chrIV_238105 4791 essential YDL126C 540 - GCAACGACGGCATATTCTTC A|187|P A|187|T V|186|L V|186|I CDC48 Cell Division Cycle 835.0 0 0 0 0 -0.11509568315299824 P25694 0.08331990987062454 0.5722559690475464 0.03663982078433037 0.4803955852985382 0.7663999795913696 -0.6872000098228455 48.14281589802806 50.0 0.0 no 1551 chrIV_238136r 4792 essential YDL126C 506 + ACAAGTCGAATTCAAGGTTG Q|170|E Q|170|* silent|GTC>GTG|V|171 silent|GTC>GTT|V|171 CDC48 Cell Division Cycle 835.0 0 0 0 0 -1.1776374902888938 P25694 1.0 40.3679205880112 40.0 0.0 no 1552 chrIV_238496r 4806 essential YDL126C 146 + TGCTATTAATTCTAACACCA A|50|G A|50|V CDC48 Cell Division Cycle 835.0 0 0 0 0 1.065944905341672 P25694 0.32926443219184875 0.4869854748249054 40.83140749868875 30.0 0.0 no 1553 chrIV_238627r 4812 essential YDL126C 15 + AAACCACTTTTGGACGCCTC P|7|A P|7|S P|7|R P|7|L CDC48 Cell Division Cycle 835.0 0 1 0 0 0.12944911747902138 P25694 49.94087876732005 50.0 0.0 no 1554 chrIV_246022r 4814 essential YDL120W 102 - TTCTTTTTATTTGTTACAGC K|40|N silent|AAG>AAA|K|40 YFH1 Yeast Frataxin Homolog 174.0 0 0 0 0 0.6225689125374204 Q07540 0.4874942004680634 40.69368564428749 25.0 1.0 no 1555 chrIV_246208r 4820 essential YDL120W 288 - TCTACATCAGGTATACAATC E|103|Q E|103|K V|102|L V|102|I YFH1 Yeast Frataxin Homolog 174.0 0 0 0 0 -0.6036674717013668 Q07540 0.0368235781788826 0.029137492179870605 0.2232365906238556 0.29087623953819275 -0.4346399903297424 -0.9164599776268004 -0.684220016002655 -0.5245400071144104 -0.12758000195026398 -0.8469399809837341 -0.4221999943256378 -0.8889999985694885 40.43942349985872 35.0 1.0 no 1556 chrIV_246220r 4822 essential YDL120W 300 - CCATGGCTTAGCTCTACATC G|107|R G|107|S S|105|T S|105|N YFH1 Yeast Frataxin Homolog 174.0 0 0 0 0 -0.7096671176895809 Q07540 0.0 0.0 0.29529818892478943 0.2812827527523041 3.200400114059448 3.115040063858032 -1.0115000009536743 -0.3680199980735779 -1.024799942970276 -0.36739999055862427 52.804679258407994 50.0 1.0 no 1557 chrIV_246237r 4824 essential YDL120W 317 - TTTCCAATGTCATTACGCCA E|112|Q E|112|K L|111|F silent|TTG>TTA|L|111 YFH1 Yeast Frataxin Homolog 174.0 0 0 0 0 0.1891722224433124 Q07540 0.352909654378891 0.441395103931427 0.04847786575555802 -0.1281999945640564 -0.5864800214767456 2.27396011352539 -0.2879999876022339 -0.7020000219345093 49.13803304563203 40.0 1.0 no 1558 chrIV_246298r 4826 essential YDL120W 378 - GCCAACCAAATTTGCTTATT L|132|F silent|TTG>TTA|L|132 A|133|P A|133|T YFH1 Yeast Frataxin Homolog 174.0 0 0 0 0 0.29009570949401176 Q07540 0.1499769538640976 0.06808456778526306 0.0891045555472374 1.3735799789428709 2.0386400222778316 -0.4138000011444092 2.027139902114868 -0.37095999717712397 44.97998460641953 35.0 1.0 no 1559 chrIV_263517 4827 essential YDL111C 574 - TAGCATATTGTTGCCTACAA M|197|I M|197|I RRP42 Ribosomal RNA Processing 265.0 0 0 0 0 0.4010515076091992 Q12277 0.9802876114845276 0.9802876114845276 0.4589000046253204 0.4589000046253204 0.23010000586509705 0.23010000586509705 45.17128928529002 35.0 0.0 no 1560 chrIV_263615r 4831 essential YDL111C 473 + TTCAGCTTTTGACGACTTAG S|159|* S|159|L A|160|G A|160|V RRP42 Ribosomal RNA Processing 265.0 0 0 0 0 0.7838902749402015 Q12277 0.0 0.3547942638397217 0.13808338344097135 0.840179979801178 0.4092400074005127 0.5679200291633606 0.4990000128746033 0.1695999950170517 44.221871129755705 40.0 0.0 no 1561 chrIV_263898 4835 essential YDL111C 193 - CACATGATGATCCACAACTT V|71|L V|71|M RRP42 Ribosomal RNA Processing 265.0 0 0 0 0 0.4928966106541599 Q12277 0.3061801493167877 0.10642806440591812 -0.2012600004673004 -0.038199998438358314 -0.5725600123405457 -0.6233400106430054 43.64754181881489 40.0 0.0 no 1562 chrIV_263946 4836 essential YDL111C 145 - TCCATCACTAGCTATAATTC G|55|R G|55|R G|55|A G|55|E RRP42 Ribosomal RNA Processing 265.0 0 0 0 0 -0.11706317824128296 Q12277 0.0 0.0 0.0 0.0 3.3639400005340576 3.3639400005340576 3.7658998966217037 4.0980000495910645 43.486757729650094 35.0 0.0 no 1563 chrIV_263947r 4837 essential YDL111C 141 + TCCAGAATTATAGCTAGTGA silent|TCC>TCG|S|48 silent|TCC>TCT|S|48 S|48|C S|48|F RRP42 Ribosomal RNA Processing 265.0 0 0 0 0 -0.1032900182280752 Q12277 0.010445350781083107 0.004306047223508358 1.0417399406433103 11.965120315551758 42.98779279150853 35.0 0.0 no 1564 chrIV_263974r 4838 essential YDL111C 114 + GACTTCCTACCAAGTTCCAA D|39|E silent|GAC>GAT|D|39 F|40|L silent|TTC>TTT|F|40 RRP42 Ribosomal RNA Processing 265.0 0 0 0 0 0.6451404397486157 Q12277 0.2697695195674896 0.0 0.5105000138282776 2.3417201042175293 1.4183399677276611 50.41012584718885 45.0 0.0 no 1565 chrIV_264034 4840 essential YDL111C 57 - CTTCCATCGGGCCTAATTGA G|25|A G|25|E G|25|R G|25|R RRP42 Ribosomal RNA Processing 265.0 0 0 0 0 -3.424435046894465 Q12277 1.0 0.3250255882740021 0.2828699052333832 0.2828699052333832 2.659199953079224 2.677680015563965 2.045919895172119 2.045919895172119 52.68360503906462 50.0 0.0 yes 1566 chrIV_264037r 4841 essential YDL111C 51 + ACGCCTTCAATTAGGCCCGA P|19|A P|19|S T|18|R T|18|M RRP42 Ribosomal RNA Processing 265.0 0 0 0 0 0.4293156679060196 Q12277 0.07253245264291762 0.21838316321372986 0.5391605496406555 0.12631389498710632 0.7749000191688538 0.9341999888420104 -0.5947999954223633 -0.1726599931716919 55.93433181464144 55.00000000000001 0.0 no 1567 chrIV_264045r 4842 essential YDL111C 43 + TAGCAAGCACGCCTTCAATT A|16|G A|16|V RRP42 Ribosomal RNA Processing 265.0 0 0 0 0 0.3528975682937585 Q12277 0.3594401478767395 0.2710913419723511 0.4844799935817719 -0.14433999359607694 1.4481600522994995 0.5505800247192383 49.21807075954769 45.0 0.0 no 1568 chrIV_267826 4845 essential YDL108W 35 + TACTTATGCGGTTGTTTACT T|13|S T|13|I KIN28 protein KINase 306.0 0 1 0 0 -0.5766290896559044 P06242 45.47741820420607 35.0 1.0 no 1569 chrIV_267968r 4847 essential YDL108W 180 - TCTATTAGTTCTATGACGTT D|67|H D|67|N KIN28 protein KINase 306.0 0 0 0 0 -0.23102364404011885 P06242 41.78132761100079 30.0 1.0 no 1570 chrIV_268246r 4856 essential YDL108W 458 - TACTTGTCAGTATCTCATGT S|159|T S|159|N KIN28 protein KINase 306.0 0 1 0 0 0.5524812530107542 P06242 45.79314224230888 35.0 1.0 no 1571 chrIV_268385r 4860 essential YDL108W 597 - TCATTCTGTCCTGGTAAATA D|206|H D|206|N Q|204|H silent|CAG>CAA|Q|204 KIN28 protein KINase 306.0 0 0 0 0 -0.5055283678705367 P06242 44.508263333151035 35.0 1.0 no 1572 chrIV_268414 4861 essential YDL108W 623 + TCAAATGGAAGTAACGTTCA Q|209|E Q|209|* KIN28 protein KINase 306.0 0 0 0 0 -0.4679105001864509 P06242 38.268558167892365 35.0 1.0 no 1573 chrIV_268437r 4862 essential YDL108W 649 - TCTATCTGTAGGTGTCCCTA R|223|T R|223|K D|222|H D|222|N KIN28 protein KINase 306.0 0 0 0 0 1.0812818174996892 P06242 54.61603185221617 45.0 1.0 no 1574 chrIV_268448r 4864 essential YDL108W 660 - TCGGGCCAATCTCTATCTGT E|227|Q E|227|K W|225|C W|225|* KIN28 protein KINase 306.0 0 0 0 0 -1.3814744966107773 P06242 54.00745386963587 50.0 1.0 no 1575 chrIV_268467r 4865 essential YDL108W 679 - CGTCATAAAGGAAGAAACTT M|232|I M|232|I KIN28 protein KINase 306.0 0 0 0 0 -2.425904899031126 P06242 35.59834022352743 35.0 1.0 yes 1576 chrIV_272517r 4867 essential YDL105W 131 - AAACTTTAAATTCTAGCTGG V|50|L V|50|I NSE4 Non-SMC Element 402.0 0 0 0 0 1.5361496958465932 P43124 0.14646880328655246 0.864716112613678 36.22405262742717 30.0 1.0 no 1577 chrIV_272594r 4869 essential YDL105W 208 - AACACCTATATCTCCTGTTC V|76|L V|76|I G|75|A G|75|D NSE4 Non-SMC Element 402.0 0 0 0 0 -0.13912045578044685 P43124 0.12634985148906708 0.8544384837150574 0.4495466351509094 0.5829246044158936 47.7380244618966 40.0 1.0 no 1578 chrIV_272645r 4870 essential YDL105W 259 - ACCAATAACCTTATTGAATA G|93|R G|93|S G|93|A G|93|D NSE4 Non-SMC Element 402.0 0 0 0 0 0.17587022397302174 P43124 0.02457576245069504 0.2378765791654587 0.054225437343120575 0.15309354662895205 37.21674660239564 25.0 1.0 no 1579 chrIV_273090 4873 essential YDL105W 701 + CCCAATTACCGACCATTTAA P|235|R P|235|L P|235|A P|235|S NSE4 Non-SMC Element 402.0 0 0 0 0 0.6648772899272904 P43124 0.6133829355239868 0.5667356252670288 1.0 0.996262550354004 46.82041581489227 40.0 1.0 no 1580 chrIV_273091 4875 essential YDL105W 702 + CCAATTACCGACCATTTAAT P|235|R P|235|L NSE4 Non-SMC Element 402.0 0 0 0 0 0.3195430074110332 P43124 0.6133829355239868 0.5667356252670288 43.494132338949896 35.0 1.0 no 1581 chrIV_273243r 4880 essential YDL105W 857 - AACATTTCTTGACCTGTTCA C|292|S C|292|Y NSE4 Non-SMC Element 402.0 0 0 0 0 -0.19565572019062832 P43124 0.17731477320194244 0.011716686189174652 45.44520766367469 35.0 1.0 no 1582 chrIV_273244r 4881 essential YDL105W 858 - AAACATTTCTTGACCTGTTC C|292|S C|292|Y NSE4 Non-SMC Element 402.0 0 0 0 0 0.15790559423693934 P43124 0.17731477320194244 0.011716686189174652 42.605638062389225 35.0 1.0 no 1583 chrIV_275515 4884 essential YDL103C 1047 - TTCTTCTTCGCAATGTGATA K|355|N silent|AAG>AAA|K|355 K|354|N silent|AAG>AAA|K|354 QRI1 477.0 0 0 0 0 0.2253687666484758 P43123 0.9355990290641784 0.9355990290641784 0.0 0.07046572118997574 0.5821999907493591 1.3913999795913696 44.430777556805076 35.0 0.0 no 1584 chrIV_275668 4887 essential YDL103C 894 - TCAGAATATTCTATGACACA E|305|Q E|305|K QRI1 477.0 0 0 0 0 0.6226868323039357 P43123 0.956179976463318 0.9475290179252625 0.0 0.0 37.932001080456466 30.0 0.0 no 1585 chrIV_275733 4888 essential YDL103C 829 - ATCTCTCTTTCTAACGGCTT D|283|H D|283|N R|282|T R|282|K QRI1 477.0 0 0 0 0 1.0160456985946464 P43123 0.9486550092697144 0.956179976463318 0.932735025882721 0.955805003643036 0.11083918064832687 1.0 0.8838151693344116 0.9670507907867432 0.3319999873638153 -0.04740000143647194 48.83593329125148 40.0 0.0 no 1586 chrIV_275882 4894 essential YDL103C 680 - ACTTGTTTTCCTTGATGGCA K|233|N silent|AAG>AAA|K|233 QRI1 477.0 0 0 0 0 0.0009330866042722152 P43123 0.9355990290641784 0.5045378804206848 50.73603464996546 40.0 0.0 no 1587 chrIV_275964 4896 essential YDL103C 598 - ATGCTTCCCGGTTAAATCAA K|205|N silent|AAG>AAA|K|205 silent|GGG>GGC|G|204 silent|GGG>GGA|G|204 QRI1 477.0 0 1 0 0 0.6225388970198948 P43123 0.9355990290641784 0.10884199291467668 0.9922000169754028 46.99183572072616 40.0 0.0 no 1588 chrIV_275971r 4897 essential YDL103C 588 + CTGCCTGCCTTTGATTTAAC P|198|A P|198|S P|198|R P|198|L QRI1 477.0 0 0 0 0 0.9307935993116592 P43123 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.0 0.0 0.0 0.0 50.11803875262762 45.0 0.0 no 1589 chrIV_276034r 4899 essential YDL103C 525 + TTTCAAGAACACAATTATTT Q|177|E Q|177|* QRI1 477.0 0 0 0 0 -0.3012376966369006 P43123 0.9590039849281312 1.0 33.08798758062733 20.0 0.0 no 1590 chrIV_276085 4903 essential YDL103C 477 - CCTGATGTCATAATATACCA G|166|R G|166|S QRI1 477.0 0 0 0 0 0.17737310449792998 P43123 0.941340982913971 0.951104998588562 0.15325286984443665 0.10871434956789017 43.36270409413054 35.0 0.0 no 1591 chrIV_276196 4907 essential YDL103C 366 - CCAATGTCGTAACAGCCCTT G|129|R G|129|R QRI1 477.0 0 0 0 0 -0.3194398292799417 P43123 0.941340982913971 0.941340982913971 0.003204982494935393 0.003204982494935393 52.64485814371477 50.0 0.0 no 1592 chrIV_276346 4916 essential YDL103C 216 - TCGTACGAAGTAGGGGGCAA E|79|Q E|79|K silent|TCG>TCC|S|77 silent|TCG>TCA|S|77 QRI1 477.0 0 0 0 0 -0.1938780291270318 P43123 0.956179976463318 0.9475290179252625 0.38779065012931824 0.5956728458404541 49.64501344768695 55.00000000000001 0.0 no 1593 chrIV_276389r 4917 essential YDL103C 170 + CTCACTAGCTAACTCTTCTA S|58|* S|58|L L|59|V silent|CTA>TTA|L|59 QRI1 477.0 0 0 0 0 -0.38020509430298616 P43123 0.9298099875450134 0.9512209892272948 0.09286180883646013 0.2839025557041168 0.12880000472068787 46.186904401838724 40.0 0.0 no 1594 chrIV_276458 4919 essential YDL103C 104 - TCTTGGAAGATATTTGCTCC K|41|N silent|AAG>AAA|K|41 QRI1 477.0 0 0 0 0 0.3318746653516321 P43123 0.9355990290641784 0.2632361054420471 0.1324000060558319 45.923315376762325 40.0 0.0 no 1595 chrIV_276893r 4921 essential YDL102W 24 - TCGATCTTCACATCAACCAT D|15|H D|15|N K|13|N silent|AAG>AAA|K|13 POL3 POLymerase 1097.0 0 0 0 0 0.5795084726362243 P15436 0.8784540295600891 1.0258300304412842 1.0091300010681152 46.0808617648786 40.0 1.0 no 1596 chrIV_277275r 4930 essential YDL102W 406 - GACACCAAAAAACCTTACCA V|142|L V|142|I G|141|A G|141|D POL3 POLymerase 1097.0 0 0 0 0 -1.4298588230887643 P15436 0.8291440010070801 0.9054369926452636 0.6597189903259277 0.5727769732475281 0.13627365231513974 0.1793111264705658 0.02129730582237244 0.005140472203493118 42.06855939795014 40.0 1.0 no 1597 chrIV_277313 4931 essential YDL102W 441 + TCTGTACTTTGTAATGTTAC S|148|C S|148|F L|150|V L|150|F POL3 POLymerase 1097.0 0 0 0 0 1.1439317937037856 P15436 0.5645989775657654 0.5388249754905701 0.8560709953308105 0.8079869747161865 0.0014121123822405937 0.0007051844149827957 0.21986165642738345 0.053616534918546684 39.57038002804751 30.0 1.0 no 1598 chrIV_277519 4937 essential YDL102W 647 + ATACGTCACCTATCCGCATA Y|217|* silent|TAC>TAT|Y|217 silent|GTC>GTG|V|218 silent|GTC>GTT|V|218 POL3 POLymerase 1097.0 0 0 0 0 -0.5464798328790136 P15436 50.80129265966172 45.0 1.0 no 1599 chrIV_277572 4940 essential YDL102W 700 + GTCATCTTTCATTCAACTCG H|235|D H|235|Y L|236|V L|236|F POL3 POLymerase 1097.0 0 0 0 0 -0.08014987383155038 P15436 0.9936540126800536 0.9940099716186525 0.9736109972000122 0.9820629954338074 0.23242340981960294 1.0 0.5387352705001831 0.7164498567581177 45.19522875348577 40.0 1.0 no 1600 chrIV_277674r 4942 essential YDL102W 805 - TCCTTTTGGTAATGTTATCC G|275|R G|275|R G|275|A G|275|E POL3 POLymerase 1097.0 0 0 0 0 -0.04263350983303157 P15436 0.9077479839324952 0.9077479839324952 0.952498972415924 0.9108660221099854 0.01946750283241272 0.01946750283241272 0.06456845253705977 0.03933651000261307 46.60381536393663 35.0 1.0 no 1601 chrIV_277688r 4943 essential YDL102W 819 - ATCATCGAATACTTTCCTTT M|279|I M|279|I silent|TCG>TCC|S|278 silent|TCG>TCA|S|278 POL3 POLymerase 1097.0 0 0 0 0 0.07696842060445237 P15436 0.9884650111198424 0.9884650111198424 0.8937838673591614 0.8937838673591614 42.849471214314924 30.0 1.0 no 1602 chrIV_277768 4945 essential YDL102W 896 + CCTAATAGCACATCCTGCTG L|300|V silent|CTA>TTA|L|300 POL3 POLymerase 1097.0 0 0 0 0 0.1460812629888945 P15436 0.8986120223999023 0.4800081849098206 50.954767281096174 50.0 1.0 no 1603 chrIV_277811r 4947 essential YDL102W 942 - TCAAAGGACATGATACGCAA D|321|H D|321|N POL3 POLymerase 1097.0 0 0 0 0 -0.5908616920291261 P15436 0.6276029944419861 0.697646975517273 0.0 0.0 40.13684942168778 40.0 1.0 no 1604 chrIV_277891r 4953 essential YDL102W 1022 - TACTCACAACGTTGGCAATT S|347|T S|347|N silent|GTG>GTC|V|346 silent|GTG>GTA|V|346 POL3 POLymerase 1097.0 0 0 0 0 -0.4285073104501877 P15436 0.956831991672516 0.8790720105171204 0.6090661883354187 0.3702546954154968 44.056548407103655 40.0 1.0 no 1605 chrIV_278163r 4959 essential YDL102W 1294 - CTCTTTAATTTCTTGCTTAA E|438|Q E|438|K POL3 POLymerase 1097.0 0 0 0 0 0.04500179119052383 P15436 0.9975119829177856 0.9966319799423218 0.13919970393180847 0.3428693115711212 39.43463345365689 25.0 1.0 no 1606 chrIV_278222 4960 essential YDL102W 1350 + ACCAAAAATGTCAATATTGA silent|ACC>ACG|T|451 silent|ACC>ACT|T|451 T|451|S T|451|I POL3 POLymerase 1097.0 0 0 0 0 0.8618966882005962 P15436 0.9569320082664491 0.8770989775657654 0.949518084526062 0.02694874256849289 34.20300481605966 25.0 1.0 no 1607 chrIV_278363 4962 essential YDL102W 1491 + ATCATTTCTGATCTACAAAA I|498|M silent|ATC>ATT|I|498 POL3 POLymerase 1097.0 0 0 0 0 -0.4299545996827113 P15436 0.9769229888916016 0.2328860312700272 35.743773501406906 25.0 1.0 no 1608 chrIV_278557 4968 essential YDL102W 1685 + TCAACTATTTCGAAAGTGCC Q|563|E Q|563|* L|564|V silent|CTA>TTA|L|564 POL3 POLymerase 1097.0 0 0 0 0 -1.5798277242184162 P15436 0.637470006942749 0.8254370093345642 0.014905339106917381 0.007573532406240702 42.79305859446987 40.0 1.0 no 1609 chrIV_278642 4971 essential YDL102W 1770 + ACTGTTATTGAGCCTATTCG T|591|S T|591|I POL3 POLymerase 1097.0 0 0 0 0 0.012809557130885774 P15436 0.7768750190734863 0.7676479816436768 0.022525817155838013 0.082967109978199 46.48356073343735 40.0 1.0 no 1610 chrIV_278734r 4973 essential YDL102W 1865 - TACAAAGTGTTGTATAACAT C|628|S C|628|Y POL3 POLymerase 1097.0 0 0 0 0 0.8470204342966777 P15436 0.8621640205383301 0.857155978679657 0.00655368110165 0.007881062105298042 34.5840612999919 25.0 1.0 no 1611 chrIV_284745r 4979 essential YDL098C 398 + GTGCTATCATAACTTGATAA C|134|W silent|TGC>TGT|C|134 SNU23 Small NUclear ribonucleoprotein associated 194.0 0 0 0 0 0.1461027340679888 Q12368 0.9286419749259948 0.1696455180644989 38.565908966131026 30.0 0.0 no 1612 chrIV_284765 4980 essential YDL098C 381 - CACAACTCAAACTCCTCTTG L|133|F silent|TTG>TTA|L|133 E|132|D silent|GAG>GAA|E|132 SNU23 Small NUclear ribonucleoprotein associated 194.0 0 0 0 0 -0.2426812282702112 Q12368 0.9587849974632264 0.94931298494339 0.09473754465579988 0.5156487226486206 44.28082439626554 45.0 0.0 no 1613 chrIV_284801 4981 essential YDL098C 345 - TCTCTTATATCTATAATTAA R|121|T R|121|K D|122|H D|122|N SNU23 Small NUclear ribonucleoprotein associated 194.0 0 0 0 0 0.07718059195758227 Q12368 0.932735025882721 0.955805003643036 0.9486550092697144 0.956179976463318 0.021596277132630348 0.3398589789867401 0.020146682858467102 0.0748545229434967 32.12504087705412 15.0 0.0 no 1614 chrIV_284943r 4982 essential YDL098C 200 + GAGCTTATCGTCTTTCAAGA S|68|R silent|AGC>AGT|S|68 SNU23 Small NUclear ribonucleoprotein associated 194.0 0 0 0 0 0.2244931330849058 Q12368 0.9417110085487366 0.0403263196349144 45.83013836087394 40.0 0.0 no 1615 chrIV_284986r 4983 essential YDL098C 157 + CGCTAAAAGACCTAAATAAA L|54|V silent|CTA>TTA|L|54 SNU23 Small NUclear ribonucleoprotein associated 194.0 0 0 0 0 -0.3320641848771352 Q12368 0.9512209892272948 1.0 33.367304005405735 30.0 0.0 no 1616 chrIV_286002 4989 essential YDL097C 674 - AGTCTTTATCTTCACAGTGC D|231|H D|231|N RPN6 Regulatory Particle Non-ATPase 434.0 0 0 0 0 0.003103300276861093 Q12377 0.0 0.0 48.395087319772934 40.0 0.0 no 1617 chrIV_286119 4996 essential YDL097C 557 - TGGCTAGATTCCTCAGTTTA A|192|P A|192|T RPN6 Regulatory Particle Non-ATPase 434.0 0 0 0 0 -1.7707117271181152 Q12377 1.0 0.1097393035888672 -1.7873599529266355 -0.18469999730587008 49.946532465492794 40.0 0.0 no 1618 chrIV_286402 5000 essential YDL097C 274 - TTTCAATACCTTTACCGTTT L|97|F silent|TTG>TTA|L|97 RPN6 Regulatory Particle Non-ATPase 434.0 0 1 0 0 0.033993924567143896 Q12377 0.005542564671486615 44.60949743549536 30.0 0.0 no 1619 chrIV_286543 5005 essential YDL097C 133 - TCTACGCTTGTCATCCACAC R|51|T R|51|K R|50|P R|50|H RPN6 Regulatory Particle Non-ATPase 434.0 0 1 0 0 -2.297845499735372 Q12377 0.33665668964385986 0.3777444362640381 0.2753431499004364 0.13127239048480988 52.1457809178301 50.0 0.0 yes 1620 chrIV_286660r 5008 essential YDL097C 13 + GTTCGAAATTAGAAGAGGCC S|6|W S|6|L RPN6 Regulatory Particle Non-ATPase 434.0 0 1 0 0 0.3579583337700328 Q12377 0.012503568083047869 0.21813589334487915 43.13937087788207 45.0 0.0 no 1621 chrIV_292858 5012 essential YDL092W 77 + ACATATAACTGTGCGTCTAA H|27|D H|27|Y SRP14 Signal Recognition Particle 146.0 0 1 0 0 0.4571381496191688 P38985 0.1716892421245575 0.06435086578130722 41.36179161508443 35.0 1.0 no 1622 chrIV_292935r 5015 essential YDL092W 157 - TACATCATAGTCAGGATGGT V|59|L V|59|I D|58|H D|58|N SRP14 Signal Recognition Particle 146.0 0 1 0 0 -1.1237705362387689 P38985 0.4489638507366181 0.5691571235656738 0.053016800433397286 0.1626378744840622 -0.6793799996376038 -0.585860013961792 45.711977649431326 40.0 1.0 no 1623 chrIV_295487 5020 high_effect YDL090C 823 - TTCAACATTTATTTGGTCCA E|281|Q E|281|K V|280|L V|280|I RAM1 RAS protein and A-factor Maturation 431.0 0 0 0 0 0.4749202140660268 P22007 0.15404272079467773 0.3812741935253143 0.5438091754913329 0.7794559001922607 -0.02199999988079071 -0.6741999983787537 43.55332960623082 30.0 0.0 no 1624 chrIV_295511r 5021 high_effect YDL090C 796 + CAGCTAGTCTAGCAATTTTA A|267|G A|267|V RAM1 RAS protein and A-factor Maturation 431.0 0 0 0 0 0.8637040666181532 P22007 0.0 0.0 44.052335325293825 35.0 0.0 no 1625 chrIV_295504r 5022 high_effect YDL090C 803 + TCTAGCAATTTTAAGGTCCA L|269|V silent|CTA>TTA|L|269 A|270|G A|270|V RAM1 RAS protein and A-factor Maturation 431.0 0 0 0 0 0.6913250592381998 P22007 0.0360342375934124 0.41118279099464417 0.5744319558143616 44.81111027482342 35.0 0.0 no 1626 chrIV_295713r 5026 high_effect YDL090C 594 + TTCAAGACCTGTTTAGAAGT F|199|L silent|TTC>TTT|F|199 RAM1 RAS protein and A-factor Maturation 431.0 0 0 0 0 -0.5155131596613699 P22007 0.0 42.414214466414535 35.0 0.0 no 1627 chrIV_295805 5029 high_effect YDL090C 505 - TCCATCTATGTTATCGCAAA G|175|R G|175|R G|175|A G|175|E RAM1 RAS protein and A-factor Maturation 431.0 0 0 0 0 0.4430745780469017 P22007 0.5249994993209839 0.5249994993209839 0.7631367444992065 1.0 43.98952009374977 35.0 0.0 no 1628 chrIV_295899r 5038 high_effect YDL090C 408 + CTCTTTACTATTAGTCCTTC silent|CTC>CTG|L|137 silent|CTC>CTT|L|137 RAM1 RAS protein and A-factor Maturation 431.0 0 0 0 0 -0.5922649363111877 P22007 45.82535493346893 35.0 0.0 no 1629 chrIV_300574r 5052 essential YDL087C 403 + AACTAGATGTCTTGGACGTG L|136|V silent|CTA>TTA|L|136 LUC7 Lethal Unless Cap-binding complex is produced 261.0 0 0 0 0 -0.02627228168568585 Q07508 0.2482472658157349 44.064071803676306 45.0 0.0 no 1630 chrIV_300757 5055 essential YDL087C 223 - CTCGTACTGAATTTTATGCT E|81|Q E|81|K Q|79|H silent|CAG>CAA|Q|79 LUC7 Lethal Unless Cap-binding complex is produced 261.0 0 1 0 0 -0.5524331568784296 Q07508 0.05275115743279457 0.04955371841788292 0.09168075025081636 42.882119046149676 35.0 0.0 no 1631 chrIV_300848r 5062 essential YDL087C 129 + ATCTGCAAGTCATACCTTGT I|44|M silent|ATC>ATT|I|44 C|45|W silent|TGC>TGT|C|45 LUC7 Lethal Unless Cap-binding complex is produced 261.0 0 0 0 0 -0.3520825690212065 Q07508 0.02088664285838604 0.0 48.84610286473014 40.0 0.0 no 1632 chrIV_300913r 5064 essential YDL087C 64 + ACTTCAGTTTCCGCCACAAC D|22|E silent|GAC>GAT|D|22 F|23|L silent|TTC>TTT|F|23 LUC7 Lethal Unless Cap-binding complex is produced 261.0 0 0 0 0 0.4701482707655292 Q07508 0.8755061626434326 0.7018846273422241 52.4773500257777 50.0 0.0 no 1633 chrIV_305463r 5077 essential YDL084W 229 - TTCAAAACCACAGTCAATGA E|83|Q E|83|K SUB2 SUppressor of Brr1-1 446.0 0 0 0 0 -1.0228893862021515 Q07478 0.956179976463318 0.9475290179252625 0.006988368928432465 0.006951550953090191 39.54084108755933 35.0 1.0 no 1634 chrIV_305600 5084 essential YDL084W 363 + CAACAATTGGACCCTGTTCC Q|123|E Q|123|* SUB2 SUppressor of Brr1-1 446.0 0 0 0 0 -0.20393105814211432 Q07478 0.9590039849281312 0.06672392785549164 50.26866883299607 50.0 1.0 no 1635 chrIV_305792 5089 essential YDL084W 555 + CACATTGTTGTTGCAACTCC H|186|Q silent|CAC>CAT|H|186 SUB2 SUppressor of Brr1-1 446.0 0 0 0 0 0.016515093888852084 Q07478 0.9588389992713928 0.15784016251564026 48.679264717637345 45.0 1.0 no 1636 chrIV_305810r 5090 essential YDL084W 576 - ACTAACGCTTTTAAACGACC V|199|L V|199|M silent|GCG>GCC|A|197 silent|GCG>GCA|A|197 SUB2 SUppressor of Brr1-1 446.0 0 1 0 0 0.19473483170030406 Q07478 0.9539830088615416 0.9587630033493042 0.2156988680362701 0.11203018575906754 -1.580880045890808 -2.283499956130981 41.388556581112475 40.0 1.0 no 1637 chrIV_306029r 5095 essential YDL084W 795 - TCATCGACGAAAATTTCCAA D|272|H D|272|N D|271|H D|271|N SUB2 SUppressor of Brr1-1 446.0 0 0 0 0 0.016170845950949947 Q07478 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.020465333014726642 0.044670645147562034 0.021178247407078743 0.04055839404463768 -0.3659000098705292 -0.0053599998354911796 39.24141296850212 35.0 1.0 no 1638 chrIV_306227 5098 essential YDL084W 990 + TTTCCGGCTATCACCGTTCA P|332|A P|332|S P|332|R P|332|L SUB2 SUppressor of Brr1-1 446.0 0 0 0 0 -1.1261657878431142 Q07478 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.09063724428415297 0.23717527091503146 0.019553806632757187 0.012659951113164423 55.62461235180014 50.0 1.0 no 1639 chrIV_306230r 5099 essential YDL084W 996 - TGACCATGAACGGTGATAGC G|338|A G|338|D G|338|R G|338|S SUB2 SUppressor of Brr1-1 446.0 0 1 0 0 -0.13858995186960044 Q07478 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.9373608231544496 0.06285115331411363 0.4204508364200592 0.9072397351264954 46.557427268383435 50.0 1.0 no 1640 chrIV_337723 5104 essential YDL064W 126 + GCTGGTATCCCAGGCAAAGA A|43|G A|43|V UBC9 UBiquitin-Conjugating 157.0 0 0 0 0 -0.10554218550180762 P50623 0.9484469890594482 0.9504740238189696 0.011989923194050787 0.08846056461334229 1.4163000583648682 1.681380033493042 1.6546159982681274 1.3916820287704468 54.473068796765006 55.00000000000001 1.0 no 1641 chrIV_337813r 5107 essential YDL064W 219 - CCGGCTGGAAATTTAACCTT G|80|R G|80|R A|79|P A|79|T UBC9 UBiquitin-Conjugating 157.0 0 0 0 0 -0.1784439748103357 P50623 0.941340982913971 0.941340982913971 0.9573720097541808 0.9523990154266356 0.732799232006073 0.732799232006073 1.0 0.0555037185549736 3.014539957046509 3.014539957046509 -0.9942600131034852 -0.5084999799728394 -1.035773992538452 -0.2963919937610626 47.1952262996665 45.0 1.0 no 1642 chrIV_337913r 5110 essential YDL064W 319 - AACAATTTGTTTTAACGTGA V|113|L V|113|I UBC9 UBiquitin-Conjugating 157.0 0 0 0 0 0.4719434824656591 P50623 0.9539830088615416 0.9574310183525084 1.0 0.018205247819423682 -1.0135999917984009 0.3495599925518036 35.7248324439189 25.0 1.0 no 1643 chrIV_342079 5120 essential YDL060W 460 + TAGCAGACTTTGTTGTGTTT A|155|G A|155|V TSR1 Twenty S rRNA accumulation 788.0 0 0 0 0 -0.388784801901346 Q07381 0.054829485714435584 0.018001975491642952 46.249111167854316 35.0 1.0 no 1644 chrIV_342200 5121 essential YDL060W 581 + CCTCTCAGCAGTCCATGAAA silent|CTC>CTG|L|195 silent|CTC>CTT|L|195 L|195|V L|195|F TSR1 Twenty S rRNA accumulation 788.0 0 0 0 0 -0.13597490845439408 Q07381 0.042548544704914086 0.02573441155254841 51.847037919575136 50.0 1.0 no 1645 chrIV_342250r 5123 essential YDL060W 634 - GTGCTTGAAATAACTTTCTA K|217|N silent|AAG>AAA|K|217 TSR1 Twenty S rRNA accumulation 788.0 0 0 0 0 0.4914906546518426 Q07381 0.5214444994926453 38.681386503559736 30.0 1.0 no 1646 chrIV_342667r 5136 essential YDL060W 1051 - CCAATCTTCCGTGCCTTCTG W|357|S W|357|* D|356|H D|356|N TSR1 Twenty S rRNA accumulation 788.0 0 0 0 0 -3.381797733445984 Q07381 0.60136878490448 0.1053042784333229 0.3955662548542023 56.39899257575171 55.00000000000001 1.0 yes 1647 chrIV_342668r 5137 essential YDL060W 1052 - ACCAATCTTCCGTGCCTTCT W|357|S W|357|* W|357|C W|357|* TSR1 Twenty S rRNA accumulation 788.0 0 0 0 0 0.2016023583852087 Q07381 0.60136878490448 0.15339790284633634 56.93859583386529 50.0 1.0 no 1648 chrIV_343104 5152 essential YDL060W 1485 + GAACGTTTGAAAAGGTATAG R|497|G R|497|C TSR1 Twenty S rRNA accumulation 788.0 0 0 0 0 0.06362328961096536 Q07381 0.01633286476135254 0.003180092200636864 34.960414248952425 35.0 1.0 no 1649 chrIV_343344 5157 essential YDL060W 1725 + CAACTATTATTTGCTGTCTA L|577|V silent|CTA>TTA|L|577 TSR1 Twenty S rRNA accumulation 788.0 0 0 0 0 0.6176029019806648 Q07381 0.31665000319480896 41.09820313205694 30.0 1.0 no 1650 chrIV_345725r 5160 essential YDL058W 63 - TCAACTCGATCGCACAACGT E|28|Q E|28|K V|27|L V|27|I USO1 yUSOu - transport in Japanese 1790.0 0 0 0 0 -0.8006586908880171 P25386 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.04078363999724388 0.17524807155132294 0.2460643798112869 0.3303029239177704 47.03133006743877 50.0 1.0 no 1651 chrIV_345805r 5163 essential YDL058W 143 - TCACTGATTCTCTATACTGC V|54|L V|54|M silent|GTG>GTC|V|54 silent|GTG>GTA|V|54 USO1 yUSOu - transport in Japanese 1790.0 0 0 0 0 -1.085682274756057 P25386 0.9539830088615416 0.9587630033493042 0.0 0.0 45.73622618988537 40.0 1.0 no 1652 chrIV_345856 5164 essential YDL058W 191 + TACTTTGAAACGTGATTATA T|65|S T|65|I USO1 yUSOu - transport in Japanese 1790.0 0 0 0 0 0.21788588217512367 P25386 0.9491789937019348 0.9472420215606691 0.36028021574020386 0.1578601896762848 34.79558777210042 25.0 1.0 no 1653 chrIV_345917 5165 essential YDL058W 252 + ATTCTTTTCATCAGAGGCGA L|86|V L|86|F USO1 yUSOu - transport in Japanese 1790.0 0 0 0 0 -0.662587416862087 P25386 0.9512209892272948 0.9587849974632264 0.0 0.0 47.590104695027605 40.0 1.0 no 1654 chrIV_346093 5169 essential YDL058W 428 + TCACCTACTTGTTGAATTTT H|144|Q silent|CAC>CAT|H|144 H|144|D H|144|Y USO1 yUSOu - transport in Japanese 1790.0 0 0 0 0 0.6566359954685119 P25386 0.9588389992713928 0.9473130106925964 0.9489949941635132 0.18325023353099826 0.042471244931221015 0.0187640730291605 42.834419216132396 30.0 1.0 no 1655 chrIV_346213 5173 essential YDL058W 548 + TCCAACGAGCATATCCACAA P|184|R P|184|L P|184|A P|184|S USO1 yUSOu - transport in Japanese 1790.0 0 0 0 0 -0.7052183145204148 P25386 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 47.30512269220543 45.0 1.0 no 1656 chrIV_346309 5176 essential YDL058W 644 + TTCACCTCACGTTCAAAAAT S|216|* S|216|L P|217|A P|217|S USO1 yUSOu - transport in Japanese 1790.0 0 0 0 0 0.2881929297322813 P25386 0.9298099875450134 0.9562489986419678 0.9498909711837769 0.0 0.11192257702350616 0.4498559534549713 41.184288838885664 35.0 1.0 no 1657 chrIV_346490r 5181 essential YDL058W 828 - CTCAAAAGGTGTGCCAGTTT L|282|F silent|TTG>TTA|L|282 USO1 yUSOu - transport in Japanese 1790.0 0 0 0 0 0.3640727191766551 P25386 0.9587849974632264 0.0 48.1843176140701 45.0 1.0 no 1658 chrIV_346623r 5183 essential YDL058W 961 - CAACGCATTTTGATGCTTAG silent|GCG>GCC|A|326 silent|GCG>GCA|A|326 A|326|P A|326|T USO1 yUSOu - transport in Japanese 1790.0 0 0 0 0 0.6542284184129579 P25386 0.9573720097541808 0.9523990154266356 0.10160166025161743 0.3635813593864441 42.95210659672273 40.0 1.0 no 1659 chrIV_346814 5187 essential YDL058W 1149 + CCTGTAAACTCTACTGCAAA P|384|R P|384|L USO1 yUSOu - transport in Japanese 1790.0 0 0 0 0 -0.26680651839099423 P25386 0.9432820081710817 0.9430609941482544 0.012023592367768288 0.011710054241120815 42.64641926159675 40.0 1.0 no 1660 chrIV_346899r 5191 essential YDL058W 1237 - TCTTGTATCAAACGTGTGAA R|419|T R|419|K USO1 yUSOu - transport in Japanese 1790.0 0 0 0 0 -0.07702914335705242 P25386 0.932735025882721 0.955805003643036 0.0 0.0 40.049730360960325 35.0 1.0 no 1661 chrIV_346936 5192 essential YDL058W 1271 + ACTATTAAAGGCTTATTTCA L|425|V silent|CTA>TTA|L|425 USO1 yUSOu - transport in Japanese 1790.0 0 0 0 0 0.4770901789437606 P25386 0.9512209892272948 0.0 38.05861527179269 25.0 1.0 no 1662 chrIV_347097r 5194 essential YDL058W 1435 - TTCAGTGCCATCCTTCCCGT E|485|Q E|485|K USO1 yUSOu - transport in Japanese 1790.0 0 0 0 0 -1.002564752629032 P25386 0.956179976463318 0.9475290179252625 62.395112747057745 55.00000000000001 1.0 no 1663 chrIV_347394 5198 essential YDL058W 1729 + ACTTAACGTTCCTAATATAT Y|577|* silent|TAC>TAT|Y|577 T|579|R T|579|M USO1 yUSOu - transport in Japanese 1790.0 0 0 0 0 0.6538281178466723 P25386 0.9476869702339172 0.9502379894256592 0.016704881563782692 0.009059528820216656 37.962545533847496 25.0 1.0 no 1664 chrIV_347902 5204 essential YDL058W 2237 + AACTTCTTTGCAAACAGAAA T|747|S T|747|I S|748|C S|748|F USO1 yUSOu - transport in Japanese 1790.0 0 0 0 0 -0.6456741489604756 P25386 0.9491789937019348 0.9472420215606691 0.945252001285553 0.9294660091400146 0.715011715888977 0.18513166904449466 0.05687882378697395 0.06431268900632857 36.21676820329168 30.0 1.0 no 1665 chrIV_348895 5212 essential YDL058W 3230 + CTCAGAATTGACTAAAACTA S|1078|* S|1078|L USO1 yUSOu - transport in Japanese 1790.0 0 0 0 0 -0.2826537035000018 P25386 0.9298099875450134 0.3205471336841583 34.17338074763637 30.0 1.0 no 1666 chrIV_349621 5218 essential YDL058W 3956 + CACTAATTTATCTAAGGCCA T|1320|S T|1320|I USO1 yUSOu - transport in Japanese 1790.0 0 0 0 0 -0.10123546996620096 P25386 0.9491789937019348 0.9472420215606691 0.5266461968421936 0.1397547870874405 42.74677801598949 35.0 1.0 no 1667 chrIV_356074r 5223 essential YDL055C 663 + CAACCAAAGGACTTCTTGTC P|223|A P|223|S P|223|R P|223|L PSA1 361.0 0 0 0 0 -0.13900134696208355 P41940 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.0 0.0 0.0 0.0 44.3438340549734 45.0 0.0 no 1668 chrIV_356317 5228 essential YDL055C 423 - ACAATGACACCGTATTTAGA V|148|L V|148|I PSA1 361.0 0 1 0 0 -0.3786191157204306 P41940 0.9539830088615416 0.9574310183525084 0.3654865324497223 0.032915245741605766 -3.0409998893737797 0.6984000205993652 41.34996739945558 35.0 0.0 no 1669 chrIV_356377r 5232 essential YDL055C 360 + GCTGACTTCCACAAAGCTCA A|121|G A|121|V D|122|E silent|GAC>GAT|D|122 PSA1 361.0 0 1 0 0 1.3663417944551728 P41940 0.9484469890594482 0.9504740238189696 0.9532920122146606 0.12253403663635255 0.40791794657707214 1.0 1.2640000581741333 1.544800043106079 51.01438284347943 50.0 0.0 no 1670 chrIV_356473 5234 essential YDL055C 267 - ACATCTTCAGCCAATTTCAA V|96|L V|96|I D|95|H D|95|N PSA1 361.0 0 1 0 0 -0.8236891870402935 P41940 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 0.882491946220398 0.6114872694015503 0.17131377756595612 0.3240145742893219 -0.7667999863624573 -0.5979999899864197 44.97600054004864 35.0 0.0 no 1671 chrIV_356506r 5237 essential YDL055C 231 + TCTGTAGAAACTGAACCATT S|78|C S|78|F PSA1 361.0 0 0 0 0 -0.4669895379363053 P41940 0.945252001285553 0.9294660091400146 0.004872131161391735 0.010960768908262251 40.23810500267393 35.0 0.0 no 1672 chrIV_356626r 5239 essential YDL055C 111 + ATCGAGGCTTTAGCCAACGC I|38|M silent|ATC>ATT|I|38 PSA1 361.0 0 0 0 0 -1.9976840985084667 P41940 0.9598389863967896 0.04533009603619576 52.74832628947917 55.00000000000001 0.0 no 1673 chrIV_372953 5243 essential YDL045C 636 - TTACCATATAGTCCACAAAT G|218|A G|218|D G|218|R G|218|S FAD1 FAD synthetase 306.0 0 0 0 0 0.20439424507940804 P38913 0.2986807227134705 1.0 0.20776192843914032 0.7399011850357056 -0.8923400044441223 -0.682699978351593 -1.0971599817275999 -0.747439980506897 41.042133599139106 30.0 0.0 no 1674 chrIV_373054r 5246 essential YDL045C 532 + TTCAAAGAACAGATTCTAAC Q|179|E Q|179|* FAD1 FAD synthetase 306.0 0 0 0 0 0.7552416979340293 P38913 0.74072265625 1.007580041885376 33.486476169582204 30.0 0.0 no 1675 chrIV_373080 5247 essential YDL045C 509 - GCTTTAATGCTTCACCAAAT K|176|N silent|AAG>AAA|K|176 FAD1 FAD synthetase 306.0 0 0 0 0 0.5562082599419222 P38913 0.19766433537006375 0.6425600051879883 43.76174933919293 35.0 0.0 no 1676 chrIV_373198 5251 essential YDL045C 391 - TTGCCTTTGTGATTCGTATA R|136|S silent|AGG>AGA|R|136 R|136|T R|136|K FAD1 FAD synthetase 306.0 0 0 0 0 0.9183194827286184 P38913 0.21549513936042786 0.21295250952243805 1.0 0.2292400002479553 1.425719976425171 0.17316000163555145 46.95864306620297 35.0 0.0 no 1677 chrIV_373245r 5252 essential YDL045C 341 + TACATTAGAGAATTTTGTAC T|115|R T|115|I FAD1 FAD synthetase 306.0 0 0 0 0 0.2896309702412632 P38913 0.11469581723213194 0.07655885815620422 13.454999923706055 5.037360191345215 34.12203803817954 25.0 0.0 no 1678 chrIV_373524 5260 essential YDL045C 65 - TTGCTATTATCTGAGATTTC A|28|P A|28|T FAD1 FAD synthetase 306.0 0 0 0 0 0.5587255407697547 P38913 0.27219492197036743 0.5961660742759705 2.0836000442504883 0.4770399928092957 1.991163969039917 0.8650379776954651 40.62189441953387 30.0 0.0 no 1679 chrIV_375927 5262 essential YDL043C 534 - CCAGATACAATCCTAATGAG G|185|R G|185|S PRP11 Pre-mRNA Processing 266.0 0 1 0 0 -0.1171180586945046 Q07350 0.4237758815288544 1.0 41.375317626604435 40.0 0.0 no 1680 chrIV_375927r 5263 essential YDL043C 531 + CCTCTCATTAGGATTGTATC L|179|V L|179|F P|178|R P|178|L PRP11 Pre-mRNA Processing 266.0 0 0 0 0 0.15008180448341088 Q07350 0.4910129904747009 0.766322910785675 0.0 0.0 46.7036690169295 40.0 0.0 no 1681 chrIV_376023 5266 essential YDL043C 438 - AAACCTACTGAACCGTTCTT G|152|A G|152|D G|152|R G|152|S PRP11 Pre-mRNA Processing 266.0 0 0 0 0 -0.19160188829463554 Q07350 0.0 0.0 0.0 0.0 45.012872279062385 40.0 0.0 no 1682 chrIV_376129 5269 essential YDL043C 332 - GTCGGAAATCATGAGTTGTT R|117|P R|117|Q PRP11 Pre-mRNA Processing 266.0 0 0 0 0 0.5349055474101699 Q07350 0.2836340665817261 0.6014943122863771 43.63568663783303 40.0 0.0 no 1683 chrIV_376298 5273 essential YDL043C 163 - ATTCTTGTAAATGTACGGAT K|60|N silent|AAG>AAA|K|60 PRP11 Pre-mRNA Processing 266.0 0 0 0 0 0.09481085696354784 Q07350 0.00993180088698864 38.88231721181211 30.0 0.0 no 1684 chrIV_376371r 5275 essential YDL043C 87 + GTCGAATCATTACTTAGTAA silent|GTC>GTG|V|30 silent|GTC>GTT|V|30 PRP11 Pre-mRNA Processing 266.0 0 0 0 0 0.5763721329960756 Q07350 38.145699002650865 30.0 0.0 no 1685 chrIV_376400r 5276 essential YDL043C 58 + CTCAGTTTAACTTACAACGA Q|21|E Q|21|* PRP11 Pre-mRNA Processing 266.0 0 1 0 0 -0.3847696902308945 Q07350 1.0 39.67743434673957 35.0 0.0 no 1686 chrIV_394314r 5282 essential YDL031W 100 - ATCACTCTCACTATCATTTA D|40|H D|40|N S|39|T S|39|N DBP10 Dead Box Protein 995.0 0 0 0 0 0.7514917431114765 Q12389 42.735930919345996 30.0 1.0 no 1687 chrIV_394387r 5285 essential YDL031W 173 - AGCTGTACTCGATCACATCC S|64|T S|64|N DBP10 Dead Box Protein 995.0 0 0 0 0 1.308623449153221 Q12389 51.454279596481854 50.0 1.0 no 1688 chrIV_394502r 5286 essential YDL031W 288 - TCATCTGACATTTCTAACAT D|103|H D|103|N D|102|H D|102|N DBP10 Dead Box Protein 995.0 0 1 0 0 0.5257912525485045 Q12389 0.02315863966941833 0.1771131455898285 0.017214030027389526 0.14982889592647552 40.220334671357755 30.0 1.0 no 1689 chrIV_394535 5287 essential YDL031W 318 + GCATCTGGTAAAACTCAAAC A|107|G A|107|V S|108|C S|108|F DBP10 Dead Box Protein 995.0 0 1 0 0 0.07521344085760112 Q12389 0.39296114444732666 0.3127407133579254 0.06346026808023453 0.0937541127204895 39.117028037739146 40.0 1.0 no 1690 chrIV_394554r 5289 essential YDL031W 340 - GACATCATCCTCATCATCAC V|120|L V|120|I D|119|H D|119|N DBP10 Dead Box Protein 995.0 0 0 0 0 0.09129056632356236 Q12389 0.5878861546516418 0.4403766691684723 0.0669088214635849 0.2581622004508972 48.627068172021275 45.0 1.0 no 1691 chrIV_394720r 5292 essential YDL031W 506 - CCCTACTTTGCAAAATTAAT R|175|T R|175|K R|175|S silent|AGG>AGA|R|175 DBP10 Dead Box Protein 995.0 0 0 0 0 -1.2840959579134656 Q12389 0.13504283130168915 0.5513439178466797 0.15423190593719482 40.081443152465965 30.0 1.0 no 1692 chrIV_394720 5293 essential YDL031W 503 + CCCATTAATTTTGCAAAGTA P|169|R P|169|L P|169|A P|169|S DBP10 Dead Box Protein 995.0 0 0 0 0 0.8309867625769721 Q12389 0.0 0.0 0.0 0.0 41.378171353328646 30.0 1.0 no 1693 chrIV_394730 5294 essential YDL031W 513 + TTGCAAAGTAGGGATATTGT Q|173|E Q|173|* DBP10 Dead Box Protein 995.0 0 0 0 0 -0.5538862835602267 Q12389 1.0 41.68399132907165 35.0 1.0 no 1694 chrIV_394780 5295 essential YDL031W 563 + TGCAGCATTCATCTTGCCAA A|189|G A|189|V A|190|G A|190|V DBP10 Dead Box Protein 995.0 0 0 0 0 0.9459726491764624 Q12389 0.03184384480118752 0.0321122370660305 0.0 0.0 52.11265677946296 45.0 1.0 no 1695 chrIV_394859r 5298 essential YDL031W 645 - TGCATGGCTAATTCTCTGGA M|221|I M|221|I DBP10 Dead Box Protein 995.0 0 0 0 0 -0.045565087057618685 Q12389 0.03686311841011048 0.03686311841011048 49.537739339494756 45.0 1.0 no 1696 chrIV_394863r 5299 essential YDL031W 649 - AGTCTGCATGGCTAATTCTC Q|222|H silent|CAG>CAA|Q|222 M|221|I M|221|I DBP10 Dead Box Protein 995.0 0 0 0 0 -2.110436627052776 Q12389 0.0 0.03686311841011048 0.03686311841011048 49.78336101185033 45.0 1.0 yes 1697 chrIV_394879 5300 essential YDL031W 662 + GCAGACTTTCAACGTTTTCA Q|222|E Q|222|* T|223|S T|223|I DBP10 Dead Box Protein 995.0 0 0 0 0 0.8152395587964995 Q12389 0.0 0.03548454493284225 0.08289254456758499 46.31624920581953 40.0 1.0 no 1698 chrIV_394983r 5302 essential YDL031W 769 - TGCAATAATAACGTCTGGGT A|263|P A|263|T DBP10 Dead Box Protein 995.0 0 0 0 0 -1.570191756839571 Q12389 0.0 0.0 42.9200168381505 40.0 1.0 no 1699 chrIV_395044r 5304 essential YDL031W 830 - ACTCAACACTCTTCAAATCG E|283|Q E|283|K E|283|D silent|GAG>GAA|E|283 DBP10 Dead Box Protein 995.0 0 0 0 0 0.7421909474701982 Q12389 0.3866770267486572 0.6306947469711304 0.03580927848815918 41.02138008241275 40.0 1.0 no 1700 chrIV_395317r 5310 essential YDL031W 1103 - TTTCTTGCAAAATATATAAT E|374|Q E|374|K DBP10 Dead Box Protein 995.0 0 0 0 0 -2.1528714789987595 Q12389 0.03959200531244278 0.03689029440283775 31.004148832262732 15.0 1.0 yes 1701 chrIV_395380 5311 essential YDL031W 1163 + GCTGCAAAATAGTAACAATG L|389|V silent|CTG>TTG|L|389 Q|390|E Q|390|* DBP10 Dead Box Protein 995.0 0 1 0 0 -0.6106710529463302 Q12389 0.4709834456443786 0.6274507641792297 36.085079762054704 35.0 1.0 no 1702 chrIV_395561 5312 essential YDL031W 1344 + TCTCAACTCTTAAGAGACTG Q|450|E Q|450|* S|449|C S|449|F DBP10 Dead Box Protein 995.0 0 0 0 0 -0.22488687135145607 Q12389 0.8442819118499756 0.05825526267290115 0.10282589495182036 40.770078793052726 40.0 1.0 no 1703 chrIV_395593 5313 essential YDL031W 1376 + TTCGTACATCTACGGTACTT S|460|W S|460|L Y|461|* silent|TAC>TAT|Y|461 DBP10 Dead Box Protein 995.0 0 0 0 0 -0.919415057773338 Q12389 0.0 0.0 46.2559300600887 40.0 1.0 no 1704 chrIV_395744r 5316 essential YDL031W 1530 - ACAAAAATTTTTGATGAACC V|517|L V|517|I DBP10 Dead Box Protein 995.0 0 0 0 0 0.2607433603085573 Q12389 0.03952817991375923 0.3960050344467163 32.762351220417656 25.0 1.0 no 1705 chrIV_395783 5317 essential YDL031W 1566 + ACTGCAAGAGCCGGTAACAA T|523|S T|523|I A|524|G A|524|V DBP10 Dead Box Protein 995.0 0 0 0 0 0.03230318159683596 Q12389 0.06205019354820252 0.0066251493990421295 0.08469948917627335 0.007360438350588082 47.78592484808291 50.0 1.0 no 1706 chrIV_395840r 5318 essential YDL031W 1626 - AGCTCCAAATCTAATAGGTA E|548|D silent|GAG>GAA|E|548 E|548|Q E|548|K DBP10 Dead Box Protein 995.0 0 0 0 0 0.4676091965737569 Q12389 0.04914950206875801 1.0 0.02249985188245773 42.472742089092385 35.0 1.0 no 1707 chrIV_395981 5320 essential YDL031W 1764 + TACACAAAAAGACTCGTTCT Y|589|* silent|TAC>TAT|Y|589 T|590|R T|590|I DBP10 Dead Box Protein 995.0 0 0 0 0 -1.1168512303221692 Q12389 0.09037569165229796 0.0427190400660038 37.97060471258254 35.0 1.0 no 1708 chrIV_396011r 5326 essential YDL031W 1797 - AAGCCTTCAACATCCAGTCT G|605|A G|605|D G|605|R G|605|S DBP10 Dead Box Protein 995.0 0 0 0 0 -0.7360543256457643 Q12389 0.7630608677864075 0.6237465143203735 0.5340837240219116 0.7433808445930481 51.42746371717288 45.0 1.0 no 1709 chrIV_396141r 5327 essential YDL031W 1927 - ACTTCTCTTTAAAGATTCAG S|649|T S|649|N R|648|T R|648|K DBP10 Dead Box Protein 995.0 0 0 0 0 -1.0286526281384636 Q12389 0.016068190336227417 0.005572676192969085 0.0 0.0 37.94912214084826 30.0 1.0 no 1710 chrIV_396299r 5329 essential YDL031W 2085 - AACACTGCCATTTCATCGTC silent|GTG>GTC|V|701 silent|GTG>GTA|V|701 V|701|L V|701|M DBP10 Dead Box Protein 995.0 0 0 0 0 0.2499023428608201 Q12389 0.1516958475112915 0.047075685113668435 49.00254252479567 45.0 1.0 no 1711 chrIV_396298r 5330 essential YDL031W 2084 - ACACTGCCATTTCATCGTCT V|701|L V|701|M silent|GTG>GTC|V|701 silent|GTG>GTA|V|701 DBP10 Dead Box Protein 995.0 0 0 0 0 0.3627791422910017 Q12389 0.1516958475112915 0.047075685113668435 52.49310218685964 45.0 1.0 no 1712 chrIV_397562r 5334 essential YDL030W 28 - AATCTCCATCTCCTCCAACA E|15|D silent|GAG>GAA|E|15 E|15|Q E|15|K PRP9 Pre-mRNA Processing 530.0 0 0 0 0 -0.15130183887578444 P19736 0.9930989742279052 1.0002599954605105 0.9889079928398132 0.0 0.0 0.0 1.3307600021362305 0.7247599959373474 0.7983199954032898 52.263678357761314 45.0 1.0 no 1713 chrIV_397595r 5335 essential YDL030W 61 - CCGCTGAATTCTTTCTGCTA Q|26|H silent|CAG>CAA|Q|26 R|27|P R|27|Q PRP9 Pre-mRNA Processing 530.0 0 0 0 0 -0.14150323576618926 P19736 1.0004700422286987 0.960108995437622 0.9934489727020264 0.04112239554524422 0.0 0.0 1.8279199600219729 50.61995022324584 45.0 1.0 no 1714 chrIV_397595 5336 essential YDL030W 58 + CCATAGCAGAAAGAATTCAG silent|GCC>GCG|A|20 silent|GCC>GCT|A|20 A|22|G A|22|V PRP9 Pre-mRNA Processing 530.0 0 0 0 0 0.4227739844370865 P19736 0.9919250011444092 0.991150975227356 0.06195473298430443 0.04862155020236969 0.9972000122070312 0.8494399785995483 1.881659984588623 5.600339889526367 39.697478726626464 40.0 1.0 no 1715 chrIV_397831r 5339 essential YDL030W 297 - TCATCCTCCTGTGTCTCTTC D|106|H D|106|N D|105|H D|105|N PRP9 Pre-mRNA Processing 530.0 0 0 0 0 -0.29446580476550005 P19736 0.9899479746818542 1.0004899501800537 0.9899479746818542 1.0004899501800537 0.11839485168457033 0.5603489875793457 0.4753251969814301 0.6226399540901184 -0.7915400266647339 -0.905340015888214 -0.336080014705658 -0.5178599953651428 58.257394634337004 50.0 1.0 no 1716 chrIV_397970 5340 essential YDL030W 433 + CATCTTCTTCTGATCCATCG S|146|C S|146|F S|147|C S|147|F PRP9 Pre-mRNA Processing 530.0 0 0 0 0 -0.2172480811756291 P19736 0.9182299971580504 0.9007340073585509 0.9182299971580504 0.9007340073585509 0.0466248132288456 0.032950714230537415 0.03106484189629555 0.03861472755670548 -0.01582000032067299 -1.525480031967163 -1.2931400537490845 -4.1461400985717765 49.09813988071494 45.0 1.0 no 1717 chrIV_398192r 5341 essential YDL030W 658 - ATTCTTGCGATCCATCGGTG K|225|N silent|AAG>AAA|K|225 PRP9 Pre-mRNA Processing 530.0 0 0 0 0 -0.8329822426257366 P19736 0.95727801322937 0.35755494236946106 51.69883127304882 50.0 1.0 no 1718 chrIV_398194r 5342 essential YDL030W 660 - TCATTCTTGCGATCCATCGG D|227|H D|227|N K|225|N silent|AAG>AAA|K|225 PRP9 Pre-mRNA Processing 530.0 0 0 0 0 -1.3112601855845667 P19736 0.965224027633667 0.97645902633667 0.95727801322937 0.11704111099243165 0.4725011587142944 0.35755494236946106 51.438531587039684 50.0 1.0 no 1719 chrIV_398325 5344 essential YDL030W 788 + CTTCGAACATTCATACTGTA F|264|L silent|TTC>TTT|F|264 PRP9 Pre-mRNA Processing 530.0 0 0 0 0 0.9328464417766796 P19736 0.9677240252494812 0.035463064908981316 1.9645800590515137 41.25427355256346 35.0 1.0 no 1720 chrIV_398350 5346 essential YDL030W 813 + TCTCTTCGGTCCGAGGCAAA L|273|V L|273|F S|272|C S|272|F PRP9 Pre-mRNA Processing 530.0 0 0 0 0 1.6500527554273128 P19736 0.9703750014305116 0.9798439741134644 0.9634199738502502 0.9436050057411194 0.15842220187187195 0.0606878399848938 0.016769420355558395 0.0073285289108753204 1.059540033340454 0.1399800032377243 53.508753135380346 55.00000000000001 1.0 no 1721 chrIV_398375 5347 essential YDL030W 838 + TCTATTGCCCTTTTTGTTCG I|280|M silent|ATC>ATT|I|280 PRP9 Pre-mRNA Processing 530.0 0 0 0 0 0.17097673952723633 P19736 0.9787610173225404 0.20204561948776245 0.5171800255775452 50.95768293470468 40.0 1.0 no 1722 chrIV_398622 5350 essential YDL030W 1085 + AGCACCTGCATATGATTCGA A|363|G A|363|V P|364|A P|364|S PRP9 Pre-mRNA Processing 530.0 0 0 0 0 0.6389231637557387 P19736 0.9672009944915771 0.9664270281791688 0.9763929843902588 0.9679129719734192 0.3807695508003235 0.2584691643714905 0.07273507118225098 0.09280197322368622 0.7332000136375427 0.12605999410152435 49.495476795048255 45.0 1.0 no 1723 chrIV_398657r 5351 essential YDL030W 1123 - CTGCTCACCATCCACTTGTT E|380|D silent|GAG>GAA|E|380 E|380|Q E|380|K PRP9 Pre-mRNA Processing 530.0 0 0 0 0 -0.4158983407798743 P19736 0.9686009883880616 0.97645902633667 0.9644089937210084 0.5823777318000793 0.5076386332511902 0.7730197310447693 56.04692763242321 50.0 1.0 no 1724 chrIV_398324 5352 essential YDL030W 787 + ACTTCGAACATTCATACTGT D|263|E silent|GAC>GAT|D|263 F|264|L silent|TTC>TTT|F|264 PRP9 Pre-mRNA Processing 530.0 0 0 0 0 -0.06760007811062789 P19736 0.9707459807395936 0.9677240252494812 1.0 0.035463064908981316 1.9645800590515137 42.22878399458517 35.0 1.0 no 1725 chrIV_398692 5353 essential YDL030W 1155 + CTGCAAGAAGAGCACCTCTC Q|387|E Q|387|* PRP9 Pre-mRNA Processing 530.0 0 0 0 0 -0.005261294378140401 P19736 0.9786580204963684 1.0 50.446073307745905 55.00000000000001 1.0 no 1726 chrIV_398725 5355 essential YDL030W 1188 + GACATGCCATTGGGTCCGGA D|397|E silent|GAC>GAT|D|397 P|399|A P|399|S PRP9 Pre-mRNA Processing 530.0 0 0 0 0 0.13242518325534372 P19736 0.9707459807395936 0.9314339756965636 0.9229540228843688 0.04655224084854126 0.0 0.0 57.66707117036577 60.0 1.0 no 1727 chrIV_399572r 5358 essential YDL029W 112 - ACGTTCTTCCGCCCTCAAGA R|44|P R|44|H E|43|Q E|43|K ARP2 Actin-Related Protein 391.0 0 0 0 0 -0.3952051207067643 P32381 0.17405223846435547 0.1125924587249756 0.5750737190246582 0.4493232369422913 0.08079999685287476 -0.009399999864399431 57.22080713716542 55.00000000000001 1.0 no 1728 chrIV_399597 5359 essential YDL029W 134 + CAGCGTTGCTACACCATTAA S|46|R silent|AGC>AGT|S|46 ARP2 Actin-Related Protein 391.0 0 0 0 0 -0.3564019082372807 P32381 0.5030706524848938 -0.11620000004768373 -0.07079999893903732 48.522898684832974 45.0 1.0 no 1729 chrIV_399610 5360 essential YDL029W 147 + CCATTAAAGGACATTATGAT P|50|R P|50|L ARP2 Actin-Related Protein 391.0 0 1 0 0 -0.178832032682556 P32381 0.4924078285694122 0.3030713796615601 37.8442147207918 30.0 1.0 no 1730 chrIV_399660 5362 essential YDL029W 197 + TCTGCAAATATCTTATCCTA L|67|V silent|CTG>TTG|L|67 Q|68|E Q|68|* ARP2 Actin-Related Protein 391.0 0 1 0 0 -0.4530753737053203 P32381 0.0 0.6164495348930359 0.23199999332427976 -0.13760000467300415 41.99864002338649 30.0 1.0 no 1731 chrIV_400172r 5374 essential YDL029W 712 - CTCATACGATTCCACAAGGG E|244|Q E|244|K silent|TCG>TCC|S|242 silent|TCG>TCA|S|242 ARP2 Actin-Related Protein 391.0 0 0 0 0 -1.0766363965400079 P32381 0.2304453104734421 0.4408414363861084 47.02592314287847 50.0 1.0 no 1732 chrIV_400175r 5375 essential YDL029W 715 - TAACTCATACGATTCCACAA E|244|D silent|GAG>GAA|E|244 E|244|Q E|244|K ARP2 Actin-Related Protein 391.0 0 0 0 0 -0.32297570334940384 P32381 0.17008669674396515 0.2304453104734421 0.4408414363861084 40.988211274825225 35.0 1.0 no 1733 chrIV_400335 5382 essential YDL029W 872 + TATCAGAAGTTCCCTGTATA I|292|M silent|ATC>ATT|I|292 ARP2 Actin-Related Protein 391.0 0 0 0 0 0.14679684982573954 P32381 0.012196550145745277 -1.1261999607086182 45.490359622253656 35.0 1.0 no 1734 chrIV_401770 5387 essential YDL028C 1502 - CCATTTCATAATCTAGTAGT M|507|I M|507|I E|506|Q E|506|K 0 0 0 0 -1.2965474051024146 P54199 0.9929800033569336 0.9929800033569336 0.9376909732818604 0.9258220195770264 0.0350402407348156 0.0350402407348156 0.4958120286464691 0.09471789002418518 41.85623849387065 30.0 0.0 no 1735 chrIV_401915 5388 essential YDL028C 1357 - TCCTTTCACCTTGTAAACTC G|459|R G|459|R G|459|A G|459|E 0 0 0 0 -1.5727536959673492 P54199 0.904591977596283 0.904591977596283 0.988297998905182 0.9560530185699464 0.07550914585590363 0.07550914585590363 0.10827969759702682 0.15523894131183624 47.24114267594342 40.0 0.0 no 1736 chrIV_402051 5393 essential YDL028C 1221 - TTCTTGGTGACTGGAGGTTT K|413|N silent|AAG>AAA|K|413 0 1 0 0 -1.3683141944235613 P54199 0.9158589839935304 0.0 50.5079681321443 45.0 0.0 no 1737 chrIV_402369 5395 essential YDL028C 903 - CCAGTAGAAACTTTTCGCCT G|308|R G|308|R 0 1 0 0 0.07959950657730752 P54199 0.916221022605896 0.916221022605896 0.5521397590637207 0.5521397590637207 48.982319490317316 45.0 0.0 no 1738 chrIV_402386r 5398 essential YDL028C 883 + CCAATAATGGTTCTCAACCC silent|TCC>TCG|S|295 silent|TCC>TCT|S|295 0 0 0 0 -0.19424491100870994 P54199 47.43711813859454 45.0 0.0 no 1739 chrIV_402433r 5400 essential YDL028C 836 + ACTTTCTAGTAACAACTTAT L|280|V L|280|F S|281|C S|281|F 0 1 0 0 0.5155750147577085 P54199 0.9837629795074464 0.9189339876174928 0.8627139925956726 0.9929699897766112 1.0 0.4810530841350555 0.0875527635216713 0.19939692318439484 36.88296145771358 25.0 0.0 no 1740 chrIV_402487 5401 essential YDL028C 785 - ATTCTCTGGAACTATGTTTT E|268|Q E|268|K R|267|T R|267|K 0 0 0 0 0.7269487484646241 P54199 0.9688940048217772 1.0125900506973269 0.9856789708137512 1.0077799558639526 0.5668497681617737 1.0 0.6258373260498047 1.0 42.0621249242589 30.0 0.0 no 1741 chrIV_402658 5402 essential YDL028C 614 - TCGTTTCTTTAAAGTTTGTT silent|ACG>ACC|T|211 silent|ACG>ACA|T|211 E|210|Q E|210|K 0 0 0 1 1.3627991708110547 P54199 0.9653769731521606 0.9922829866409302 0.36017149686813354 0.6103506088256836 39.93303915817943 25.0 0.0 no 1742 chrIV_402709 5405 essential YDL028C 563 - TCTCCCTTGCATTTATTGGC E|194|Q E|194|K E|194|D silent|GAG>GAA|E|194 0 1 0 0 -0.7963233248684796 P54199 1.0155400037765503 0.9653769731521606 1.0115100145339966 0.6056562662124634 0.9179263710975648 0.6296094655990601 54.25910811263049 45.0 0.0 no 1743 chrIV_402996r 5410 essential YDL028C 273 + TCATCGCATTCAACCTTGTT S|92|* S|92|L S|93|W S|93|L 0 0 0 0 -0.9144150322178856 P54199 0.9285470247268676 0.8209779858589172 0.9704989790916444 0.30162233114242554 0.03633064404129982 0.3130192160606384 48.81531879545497 40.0 0.0 no 1744 chrIV_403182r 5417 essential YDL028C 87 + CCTCCAAAACTAAGCAATTT P|31|A P|31|S P|30|R P|30|L 0 1 0 0 -0.10380925001841224 P54199 0.8684859871864319 0.8306000232696533 0.7691540122032166 0.8032580018043518 0.0 0.0 0.044202346354722984 1.0 41.1132255035094 35.0 0.0 no 1745 chrIV_424268 5418 essential YDL017W 59 + ACAGCTCTATCATGATCTAC Q|21|E Q|21|* L|22|V L|22|F CDC7 Cell Division Cycle 507.0 0 0 0 0 -0.8022026314868608 P06243 0.43151620030403137 0.12392282485961915 0.09384145587682724 44.980942330683604 40.0 1.0 no 1746 chrIV_424245r 5420 essential YDL017W 39 - ATCATCTCTTCTTTGATTTC M|19|I M|19|I E|18|D silent|GAG>GAA|E|18 CDC7 Cell Division Cycle 507.0 0 0 0 0 1.6285664700388347 P06243 0.6612979173660278 0.6612979173660278 0.1798427402973175 43.280339578156536 30.0 1.0 no 1747 chrIV_424481 5423 essential YDL017W 272 + CAACCTGCTGTACATAATGA N|92|K silent|AAC>AAT|N|92 L|93|V silent|CTG>TTG|L|93 CDC7 Cell Division Cycle 507.0 0 0 0 0 0.5585242086707667 P06243 0.16353046894073486 0.019513871520757675 43.498413717824285 40.0 1.0 no 1748 chrIV_424458r 5424 essential YDL017W 252 - AGCTCATTATAAATTCTTTG E|90|D silent|GAG>GAA|E|90 E|90|Q E|90|K CDC7 Cell Division Cycle 507.0 0 0 0 0 0.2100299669100143 P06243 0.0 0.0 0.0 36.67280947846513 25.0 1.0 no 1749 chrIV_424519r 5425 essential YDL017W 313 - CCTTTTTGCATCACATAGAG R|111|T R|111|K CDC7 Cell Division Cycle 507.0 0 0 0 0 -0.06871540532300502 P06243 0.0 0.0 45.736804967992725 40.0 1.0 no 1750 chrIV_424520r 5427 essential YDL017W 314 - CCCTTTTTGCATCACATAGA R|111|T R|111|K R|111|S silent|AGG>AGA|R|111 CDC7 Cell Division Cycle 507.0 0 0 0 0 -1.2976491437686124 P06243 0.0 0.0 0.0 49.45915118478899 40.0 1.0 no 1751 chrIV_424614r 5430 essential YDL017W 408 - TACTTCTTGATTCCCTTGAT K|142|N silent|AAG>AAA|K|142 K|141|N silent|AAG>AAA|K|141 CDC7 Cell Division Cycle 507.0 0 0 0 0 0.4256591883469371 P06243 0.5737197995185852 0.0170688945800066 47.72612916058347 35.0 1.0 no 1752 chrIV_424602 5431 essential YDL017W 393 + TACAGGGATCTACCAATCAA Y|132|* silent|TAC>TAT|Y|132 CDC7 Cell Division Cycle 507.0 0 0 0 0 -0.3118896738609732 P06243 43.63386082090239 40.0 1.0 no 1753 chrIV_424835r 5433 essential YDL017W 629 - TCATTGAATATCCACCATCA M|216|I M|216|I CDC7 Cell Division Cycle 507.0 0 0 0 0 0.036688084678884465 P06243 0.42661404609680176 0.42661404609680176 44.925419130780604 35.0 1.0 no 1754 chrIV_424913 5434 essential YDL017W 704 + ACATAACCAAACACCTCCTA H|236|D H|236|Y N|237|K silent|AAC>AAT|N|237 CDC7 Cell Division Cycle 507.0 0 1 0 0 1.2020551123914889 P06243 0.6706389784812927 0.6672454476356506 0.9464411735534668 45.341138086105616 40.0 1.0 no 1755 chrIV_424961 5438 essential YDL017W 752 + CCACTTAAACAATGTAAATG H|252|Q silent|CAC>CAT|H|252 H|252|D H|252|Y CDC7 Cell Division Cycle 507.0 0 0 0 0 0.21595749588340205 P06243 0.2027538865804672 0.7113375663757324 0.3491388261318207 33.92869953368614 30.0 1.0 no 1756 chrIV_425004r 5439 essential YDL017W 798 - ATTCTACGCGTTTCATTTTT R|272|T R|272|K R|271|P R|271|H CDC7 Cell Division Cycle 507.0 0 0 0 0 0.43269369396841983 P06243 0.3952604830265045 0.6450755596160889 0.0 0.0 44.671980559343645 30.0 1.0 no 1757 chrIV_425067r 5443 essential YDL017W 861 - CCACACTTCATTAACACTTC C|293|S C|293|Y G|294|R G|294|R CDC7 Cell Division Cycle 507.0 0 0 0 0 -6.255244824453407 P06243 0.0 0.0 0.2301521301269531 0.2301521301269531 0.2547999918460846 0.5505999922752379 8.654899597167969 8.654899597167969 44.42124213716341 40.0 1.0 yes 1758 chrIV_425119r 5444 essential YDL017W 913 - ACTTAAAAGAATAACACCTA S|311|T S|311|N CDC7 Cell Division Cycle 507.0 0 0 0 0 0.4810501134645851 P06243 0.9100360870361328 0.05523715168237686 33.076785910702824 25.0 1.0 no 1759 chrIV_425160r 5445 essential YDL017W 954 - TCATCTAAACTTTGGAACAT D|325|H D|325|N D|324|H D|324|N CDC7 Cell Division Cycle 507.0 0 0 0 0 -0.5783833207448265 P06243 0.0 0.0 0.014371335506439209 0.1454143077135086 -0.3867999911308289 -0.4266999959945679 -0.9110000133514404 -1.6399999856948853 37.65299256540948 30.0 1.0 no 1760 chrIV_425168r 5447 essential YDL017W 962 - AATCCGCATCATCTAAACTT D|327|H D|327|N silent|GCG>GCC|A|326 silent|GCG>GCA|A|326 CDC7 Cell Division Cycle 507.0 0 0 0 0 -0.2811492094587881 P06243 0.010751480236649513 0.1126973032951355 -0.17659999430179596 -1.1432000398635864 42.87645769701726 35.0 1.0 no 1761 chrIV_425289 5452 essential YDL017W 1080 + AAACCAAACGGATATTCTAA P|362|A P|362|S P|362|R P|362|L CDC7 Cell Division Cycle 507.0 0 0 0 0 -0.2700184632975054 P06243 0.7549212574958801 0.73799067735672 0.5241960883140564 0.2833276093006134 35.889402632362874 30.0 1.0 no 1762 chrIV_425292r 5453 essential YDL017W 1086 - AATCCATTAGAATATCCGTT G|368|A G|368|E G|368|R G|368|R CDC7 Cell Division Cycle 507.0 0 0 0 0 0.3991137075365095 P06243 0.3364655375480652 0.3907724022865296 0.2152777761220932 0.2152777761220932 41.751128932992565 30.0 1.0 no 1763 chrIV_426238 5454 essential YDL015C 677 - TCTTTTGATAGTCACCCCAT K|232|N silent|AAG>AAA|K|232 TSC13 Temperature-sensitive Suppressors of Csg2 mutants 310.0 0 0 0 0 -0.3053330740199593 Q99190 0.16059258580207825 51.702938778571756 40.0 0.0 no 1764 chrIV_426252r 5455 essential YDL015C 660 + CACATTAAATTGCGCCTATG H|221|Q silent|CAC>CAT|H|221 TSC13 Temperature-sensitive Suppressors of Csg2 mutants 310.0 0 0 0 0 -0.5985959293489145 Q99190 0.0 43.01078978473771 40.0 0.0 no 1765 chrIV_426253r 5457 essential YDL015C 659 + CCACATTAAATTGCGCCTAT H|221|Q silent|CAC>CAT|H|221 H|221|D H|221|Y TSC13 Temperature-sensitive Suppressors of Csg2 mutants 310.0 0 0 0 0 -0.8117536432481209 Q99190 0.0 0.0 0.0 46.467631008441174 40.0 0.0 no 1766 chrIV_426254r 5458 essential YDL015C 658 + GCCACATTAAATTGCGCCTA H|221|D H|221|Y C|220|W silent|TGC>TGT|C|220 TSC13 Temperature-sensitive Suppressors of Csg2 mutants 310.0 0 0 0 0 0.036366652578701655 Q99190 0.0 0.0 0.00901738181710243 49.80105509308953 45.0 0.0 no 1767 chrIV_426334r 5459 essential YDL015C 578 + ATACTATTCATATTTGAAAT Y|194|* silent|TAC>TAT|Y|194 TSC13 Temperature-sensitive Suppressors of Csg2 mutants 310.0 0 0 0 0 -0.3980716054333117 Q99190 31.46032891451239 15.0 0.0 no 1768 chrIV_426387r 5460 essential YDL015C 525 + TCATTCGGTTACTTTGGCTA S|176|* S|176|L F|177|L silent|TTC>TTT|F|177 TSC13 Temperature-sensitive Suppressors of Csg2 mutants 310.0 0 0 0 0 0.1344985027333059 Q99190 0.47261697053909296 1.0 48.863615240578326 40.0 0.0 no 1769 chrIV_426551r 5461 essential YDL015C 361 + ACTATAATCCATTTTTAAAC D|121|E silent|GAC>GAT|D|121 TSC13 Temperature-sensitive Suppressors of Csg2 mutants 310.0 0 0 0 0 0.6407864669646873 Q99190 0.17888925969600675 33.55602069884088 20.0 0.0 no 1770 chrIV_426587 5462 essential YDL015C 328 - GTGCCATCTATCAACAACTG W|115|C W|115|* W|115|S W|115|* TSC13 Temperature-sensitive Suppressors of Csg2 mutants 310.0 0 0 0 0 0.4834079437618621 Q99190 46.03285105912028 45.0 0.0 no 1771 chrIV_426655r 5464 essential YDL015C 257 + AGTCTTCTTTTGTGAGTATT silent|GTC>GTG|V|87 silent|GTC>GTT|V|87 F|88|L silent|TTC>TTT|F|88 TSC13 Temperature-sensitive Suppressors of Csg2 mutants 310.0 0 0 0 0 0.2111447475471071 Q99190 0.0433746799826622 44.45387791127894 30.0 0.0 no 1772 chrIV_426675 5467 essential YDL015C 240 - ACTAATCTCCATGAAATTTG V|87|L V|87|I R|85|T R|85|K TSC13 Temperature-sensitive Suppressors of Csg2 mutants 310.0 0 0 0 0 0.3808470035553373 Q99190 0.0 0.0 0.19531555473804474 0.6140662431716919 37.46039183091113 30.0 0.0 no 1773 chrIV_426805 5468 essential YDL015C 110 - TCCTGTACTTGCTGATATTG R|43|T R|43|K R|43|S silent|AGG>AGA|R|43 TSC13 Temperature-sensitive Suppressors of Csg2 mutants 310.0 0 0 0 0 -0.6013468117833758 Q99190 0.0 0.0 0.0 46.7983109782989 40.0 0.0 no 1774 chrIV_426806r 5469 essential YDL015C 106 + ACCACAATATCAGCAAGTAC H|37|D H|37|Y N|36|K silent|AAC>AAT|N|36 TSC13 Temperature-sensitive Suppressors of Csg2 mutants 310.0 0 0 0 0 0.18318575337368576 Q99190 0.33799952268600464 0.0674414113163948 0.9259201288223268 42.82872742680326 40.0 0.0 no 1775 chrIV_426846 5470 essential YDL015C 69 - TTCAAAACATCATCTAAAGT L|29|F silent|TTG>TTA|L|29 TSC13 Temperature-sensitive Suppressors of Csg2 mutants 310.0 0 0 0 0 -0.02335804481010884 Q99190 0.06448592990636826 33.697165603207175 25.0 0.0 no 1776 chrIV_426902r 5471 essential YDL015C 10 + CCATAAAAAGCCGCTCTAAA silent|ACC>ACG|T|4 silent|ACC>ACT|T|4 TSC13 Temperature-sensitive Suppressors of Csg2 mutants 310.0 0 0 0 0 0.9784767752110726 Q99190 41.72989828643409 40.0 0.0 no 1777 chrIV_426903r 5474 essential YDL015C 9 + ACCATAAAAAGCCGCTCTAA silent|ACC>ACG|T|4 silent|ACC>ACT|T|4 T|4|S T|4|I TSC13 Temperature-sensitive Suppressors of Csg2 mutants 310.0 0 0 0 0 0.4784488939669885 Q99190 0.7207961678504944 0.18620797991752625 43.361252146431006 40.0 0.0 no 1778 chrIV_426654r 5476 essential YDL015C 258 + GTCTTCTTTTGTGAGTATTT silent|GTC>GTG|V|87 silent|GTC>GTT|V|87 F|88|L silent|TTC>TTT|F|88 TSC13 Temperature-sensitive Suppressors of Csg2 mutants 310.0 0 0 0 0 -1.009363318336658 Q99190 0.0433746799826622 44.68134962535771 30.0 0.0 no 1779 chrIV_427395r 5477 essential YDL014W 34 - GCCACCTCTGGAACCTCCAC G|18|R G|18|S G|18|A G|18|D NOP1 NucleOlar Protein 327.0 0 0 0 0 -4.630819683595752 P15646 60.930316888036145 65.0 1.0 yes 1780 chrIV_427602r 5481 essential YDL014W 241 - AACGACCTTGGCACCACCAC V|87|L V|87|I V|86|L V|86|I NOP1 NucleOlar Protein 327.0 0 1 0 0 -1.2308212034965669 P15646 0.6351403594017029 1.0 0.12937210500240326 0.1681748777627945 -1.3424999713897705 -0.3529199957847595 54.78252898517053 60.0 1.0 no 1781 chrIV_427603r 5482 essential YDL014W 242 - TAACGACCTTGGCACCACCA V|87|L V|87|I V|86|L V|86|I NOP1 NucleOlar Protein 327.0 0 1 0 0 0.06163073581621381 P15646 0.6351403594017029 1.0 0.12937210500240326 0.1681748777627945 -1.3424999713897705 -0.3529199957847595 53.86153943169189 55.00000000000001 1.0 no 1782 chrIV_427643 5483 essential YDL014W 279 + GCCGGTGTTTACATTGCTAG silent|GCC>GCG|A|94 silent|GCC>GCT|A|94 A|94|G A|94|V NOP1 NucleOlar Protein 327.0 0 0 0 0 0.12536882247693648 P15646 0.15863320231437686 0.089043989777565 0.5874199867248535 -0.2709400057792664 52.4329969814637 50.0 1.0 no 1783 chrIV_427698r 5486 essential YDL014W 337 - ACCATAAACTGATTCACCTG G|119|R G|119|S G|119|A G|119|D NOP1 NucleOlar Protein 327.0 0 1 0 0 0.4627490230544785 P15646 0.003857963718473911 0.011944965459406376 0.005435521714389324 0.019969159737229347 43.44397960077606 40.0 1.0 no 1784 chrIV_427773 5489 essential YDL014W 409 + CCAAGGTCGAATACCGTGTA silent|ACC>ACG|T|137 silent|ACC>ACT|T|137 NOP1 NucleOlar Protein 327.0 0 0 0 0 -4.346742157364054 P15646 48.81698693078926 50.0 1.0 yes 1785 chrIV_427786r 5491 essential YDL014W 425 - ATCTGAATGGGTTCCATACA R|148|T R|148|K NOP1 NucleOlar Protein 327.0 0 1 0 0 -2.1477254779555643 P15646 0.0018811603076756 0.039064712822437286 46.619079816965154 40.0 1.0 yes 1786 chrIV_427821r 5495 essential YDL014W 460 - ATCTAGACCACCCATAATAC D|160|H D|160|N NOP1 NucleOlar Protein 327.0 0 0 0 0 -2.933001816545484 P15646 0.013760644011199473 0.12206757068634032 45.55521429304729 40.0 1.0 yes 1787 chrIV_427893r 5497 essential YDL014W 532 - AACGTGAGAAACAGAAGTAC V|184|L V|184|I NOP1 NucleOlar Protein 327.0 0 0 0 0 -3.2253441889761683 P15646 0.010028831660747528 0.1882832944393158 35.997935424719174 40.0 1.0 yes 1788 chrIV_427907 5498 essential YDL014W 543 + TCTCACGTTTCAGATGTTGT H|183|D H|183|Y S|182|C S|182|F NOP1 NucleOlar Protein 327.0 0 0 0 0 -0.6159763203535711 P15646 0.0 0.0 0.0 0.0 48.16941622783242 40.0 1.0 no 1789 chrIV_428041r 5501 essential YDL014W 680 - TCAACATTCTGTATTTTTGT L|233|F silent|TTG>TTA|L|233 M|232|I M|232|I NOP1 NucleOlar Protein 327.0 0 0 0 0 0.7362814675516338 P15646 0.005659612361341715 0.1492093801498413 0.1492093801498413 0.35354000329971313 0.07865999639034271 0.07865999639034271 40.12241134678521 25.0 1.0 no 1790 chrIV_433550r 5506 essential YDL008W 56 - CGTCCTCATCAGATGTGCTA D|25|H D|25|N E|24|D silent|GAG>GAA|E|24 APC11 Anaphase Promoting Complex 165.0 0 0 0 0 -1.3519430987039882 Q12157 0.22516705095767972 0.3983506262302399 0.6056699156761169 53.199079108536814 50.0 1.0 no 1791 chrIV_433587r 5507 essential YDL008W 93 - TCGTCTTCATCATTGCCAAT E|38|Q E|38|K D|37|H D|37|N APC11 Anaphase Promoting Complex 165.0 0 0 0 0 0.8257893124581348 Q12157 0.05104756355285645 0.04054334387183189 0.13596771657466888 0.4269348680973053 49.13679878855289 40.0 1.0 no 1792 chrIV_433650 5509 essential YDL008W 153 + TGTCCAAGCTGTAAATTTCC P|53|A P|53|S P|53|R P|53|L APC11 Anaphase Promoting Complex 165.0 0 0 0 0 0.19720994258648614 Q12157 0.0 0.0 0.0 0.0 46.135871793084725 40.0 1.0 no 1793 chrIV_433675 5513 essential YDL008W 178 + ATCAATGCCCTTTAGTGATT Q|61|E Q|61|* APC11 Anaphase Promoting Complex 165.0 0 0 0 0 0.0967212985064893 Q12157 1.0 47.144300664744826 35.0 1.0 no 1794 chrIV_433682r 5514 essential YDL008W 188 - GACATAGCCCAATCACTAAA C|69|S C|69|Y APC11 Anaphase Promoting Complex 165.0 0 0 0 0 -0.7906612250837531 Q12157 0.0 0.0 43.854375044734866 40.0 1.0 no 1795 chrIV_433683r 5515 essential YDL008W 189 - TGACATAGCCCAATCACTAA C|69|S C|69|Y APC11 Anaphase Promoting Complex 165.0 0 0 0 0 -0.6839849864447058 Q12157 0.0 0.0 45.26346986513687 40.0 1.0 no 1796 chrIV_433753r 5517 essential YDL008W 259 - CATCGGACACAGTCCTTTTG silent|CCG>CCC|P|92 silent|CCG>CCA|P|92 APC11 Anaphase Promoting Complex 165.0 0 0 0 0 0.3741693248092064 Q12157 49.842964241757564 50.0 1.0 no 1797 chrIV_433781 5518 essential YDL008W 284 + GCAAACTTTCCAGCTACAGA Q|96|E Q|96|* T|97|S T|97|I APC11 Anaphase Promoting Complex 165.0 0 0 0 0 0.9454034929172992 Q12157 0.0 0.7276561856269836 0.20705346763134005 48.020625884221715 45.0 1.0 no 1798 chrIV_433829r 5519 essential YDL008W 335 - AAACTATTTCAACGAACTTT V|118|L V|118|I APC11 Anaphase Promoting Complex 165.0 0 0 0 0 0.4540915563844743 Q12157 0.8882979750633241 0.9455099701881408 34.45807886668598 25.0 1.0 no 1799 chrIV_438247r 5525 essential YDL007W 203 - ATTCTTCTTCTAATAACAAA E|74|Q E|74|K E|73|Q E|73|K RPT2 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 437.0 0 0 0 0 1.1401747191243303 P40327 0.12136414647102355 0.1471022367477417 0.27997350692749023 0.26875364780426025 33.387572616399105 20.0 1.0 no 1800 chrIV_438296r 5526 essential YDL007W 252 - TCCTCCTGCTTCTTTTCAAA E|90|D silent|GAG>GAA|E|90 E|91|Q E|91|K RPT2 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 437.0 0 0 0 0 -0.3400711820808931 P40327 0.5565401911735535 0.18255563080310824 0.24999216198921204 0.5357999801635742 0.4018000066280365 51.13384853980018 40.0 1.0 no 1801 chrIV_438353r 5528 essential YDL007W 309 - TCAAGGGTCCCAATGCTCAA E|110|Q E|110|K RPT2 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 437.0 0 0 0 0 -0.3703341120736591 P40327 0.10728875547647476 0.10856591165065764 51.795117565928926 50.0 1.0 no 1802 chrIV_438532 5531 essential YDL007W 485 + TGACGCCGATCCAATGGTTT D|163|E silent|GAC>GAT|D|163 A|164|G A|164|V RPT2 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 437.0 0 0 0 0 0.41440309073508375 P40327 1.0 0.1043660044670105 1.0 2.1744000911712646 -0.5063999891281128 0.9341999888420104 51.38838095727362 50.0 1.0 no 1803 chrIV_438578 5532 essential YDL007W 531 + ACAGAATCATACAGTGATAT T|178|R T|178|I RPT2 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 437.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.02488479631858897 P40327 0.22770719230175016 0.0860978215932846 8.397699356079103 12.851099967956545 37.403675607393104 30.0 1.0 no 1804 chrIV_438473r 5533 essential YDL007W 429 - TGCAATAACACAGAACATCC L|149|F silent|TTG>TTA|L|149 RPT2 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 437.0 0 0 0 0 -0.09043612977014297 P40327 0.005146084353327751 40.754384855169356 40.0 1.0 no 1805 chrIV_438658r 5536 essential YDL007W 614 - CCATCTCTTCATACAGTTCG M|211|I M|211|I E|210|D silent|GAG>GAA|E|210 RPT2 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 437.0 0 0 0 0 -0.42975608535779264 P40327 1.0 1.0 0.4041513502597809 0.934939980506897 0.934939980506897 48.92540850886525 45.0 1.0 no 1806 chrIV_438693r 5538 essential YDL007W 649 - ACCATAAAGAATCACACCCT G|223|R G|223|S G|223|A G|223|D RPT2 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 437.0 0 0 0 0 -6.3544771553995405 P40327 0.0 0.0 0.0 0.0 44.94093670230711 40.0 1.0 yes 1807 chrIV_438762 5539 essential YDL007W 715 + AAACATCTGCCACATTCTTA T|240|R T|240|I S|241|C S|241|F RPT2 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 437.0 0 0 0 0 -0.1184057192161149 P40327 0.0 0.0 0.009188676252961159 0.008282704278826714 44.0872545628763 35.0 1.0 no 1808 chrIV_438872r 5544 essential YDL007W 828 - TCATCAATAAATACAATACT E|283|Q E|283|K D|282|H D|282|N RPT2 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 437.0 0 0 0 0 -2.9276218208362432 P40327 0.0 0.0 0.0 0.0 0.10360000282526016 1.562999963760376 -0.8253999948501587 -1.0331000089645386 31.18735213798448 20.0 1.0 yes 1809 chrIV_439916 5549 high_effect YDL006W 7 + ATCATTCTGAAATCTTAGAA H|4|D H|4|Y S|5|C S|5|F PTC1 Phosphatase type Two C 281.0 0 1 0 0 0.9039309767628472 P35182 35.135362895352046 25.0 1.0 no 1810 chrIV_439959 5551 high_effect YDL006W 50 + AACTTATAGAGTAGGTGTGG T|18|S T|18|I PTC1 Phosphatase type Two C 281.0 0 1 0 0 0.08483612994120016 P35182 1.0 0.006791240070015192 42.16032523656878 40.0 1.0 no 1811 chrIV_440255 5554 high_effect YDL006W 346 + CTGCTGTTTGCGTATTACGT A|117|G A|117|V PTC1 Phosphatase type Two C 281.0 0 0 0 0 0.9770899365937162 P35182 0.0037357686087489132 1.0 1.694000005722046 0.8999999761581421 50.295582589599974 45.0 1.0 no 1812 chrIV_440256 5555 high_effect YDL006W 347 + TGCTGTTTGCGTATTACGTT A|117|G A|117|V PTC1 Phosphatase type Two C 281.0 0 0 0 0 -0.6650180466572615 P35182 0.0037357686087489132 1.0 1.694000005722046 0.8999999761581421 48.75405407427718 40.0 1.0 no 1813 chrIV_440460r 5557 high_effect YDL006W 554 - TTACACGACTTTTCATTATC V|191|L V|191|I R|190|P R|190|H PTC1 Phosphatase type Two C 281.0 0 1 0 0 -0.18738247105783945 P35182 0.008943318389356136 0.05566975846886635 0.0 0.0 5.4566001892089835 3.308000087738037 39.59376597120581 30.0 1.0 no 1814 chrIV_443254r 5569 essential YDL004W 228 - TCCATAACTTCAACGACACC M|82|I M|82|I E|83|Q E|83|K 0 0 0 0 -1.3958997914347644 Q12165 1.0 1.0 0.03167716786265373 0.111154206097126 0.24602000415325165 0.24602000415325165 -0.184579998254776 -0.5523599982261658 -0.4736999869346618 -0.4736999869346618 45.444081428231584 45.0 1.0 no 1815 chrIV_443287 5571 essential YDL004W 258 + TCTAAAAAATTCTTTATATC S|87|C S|87|F 0 0 0 0 -0.509817378994955 Q12165 0.001993783051148057 0.0009439894929528236 -0.017160000279545784 -0.3747200071811676 28.242732210855078 15.0 1.0 no 1816 chrIV_444740r 5574 essential YDL003W 60 - GCAAGCCATATTTGTGCTAA A|27|P A|27|T W|25|C W|25|* MCD1 Mitotic Chromosome Determinant 566.0 0 0 0 0 -1.1425926091090624 Q12158 1.0011199712753296 0.9935200214385986 0.9440850019454956 0.0 0.0 0.0 47.34760233157209 40.0 1.0 no 1817 chrIV_444805 5576 essential YDL003W 122 + ACATATTGCTGAATCAGCAA H|42|D H|42|Y MCD1 Mitotic Chromosome Determinant 566.0 0 0 0 0 -0.0064716688819650425 Q12158 0.9917020201683044 0.9918540120124816 0.6687643527984619 0.03024319745600224 41.711541290975276 35.0 1.0 no 1818 chrIV_444875 5578 essential YDL003W 192 + TACATAACTTTACGAACATC Y|65|* silent|TAC>TAT|Y|65 MCD1 Mitotic Chromosome Determinant 566.0 0 0 0 0 1.689753069898665 Q12158 35.35799772605213 30.0 1.0 no 1819 chrIV_445103r 5582 essential YDL003W 423 - TCATCTAAGAACTCTAACCC D|148|H D|148|N D|147|H D|147|N MCD1 Mitotic Chromosome Determinant 566.0 0 0 0 0 -4.497556807703192 Q12158 0.9899479746818542 1.0004899501800537 0.9899479746818542 1.0004899501800537 0.013696466572582722 0.042049124836921685 0.06797545403242111 0.6880451440811157 43.18337836341817 40.0 1.0 yes 1820 chrIV_445136r 5585 essential YDL003W 456 - TCCTGCGCCATTAAGCCCAC Q|158|H silent|CAG>CAA|Q|158 E|159|Q E|159|K MCD1 Mitotic Chromosome Determinant 566.0 0 1 0 0 -1.898954297336798 Q12158 1.0004700422286987 1.0004899501800537 0.9891330003738404 0.3595046103000641 0.0725180134177208 0.09277980029582976 59.578409206466006 60.0 1.0 no 1821 chrIV_445501 5595 essential YDL003W 818 + AATCATGTCTGAGGAGCCTA I|274|M silent|ATC>ATT|I|274 MCD1 Mitotic Chromosome Determinant 566.0 0 0 0 0 0.008495319386330413 Q12158 1.0025700330734253 0.1760983020067215 49.15261008373857 45.0 1.0 no 1822 chrIV_445560r 5598 essential YDL003W 880 - TATCGTATCTATATTGCCTG silent|ACG>ACC|T|299 silent|ACG>ACA|T|299 MCD1 Mitotic Chromosome Determinant 566.0 0 0 0 0 -0.04997139530211767 Q12158 44.10344840869976 35.0 1.0 no 1823 chrIV_445607r 5599 essential YDL003W 927 - CTTCTTGTGCCAGTTTGTTT R|315|T R|315|K MCD1 Mitotic Chromosome Determinant 566.0 0 0 0 0 -0.1153033850939388 Q12158 0.979092001914978 0.9988390207290648 0.2624630928039551 1.0 52.51311329881639 40.0 1.0 no 1824 chrIV_445926r 5603 essential YDL003W 1246 - CGCATTACTAATTACATCGT A|422|P A|422|T MCD1 Mitotic Chromosome Determinant 566.0 0 0 0 0 -1.8984253704930365 Q12158 1.0011199712753296 0.9935200214385986 0.05166487023234368 0.3000757992267609 41.706436633248295 35.0 1.0 no 1825 chrIV_453225r 5610 essential YDR002W 183 - ACTGGTTCAAAATGGATATC V|68|L V|68|M YRB1 Yeast Ran Binder 201.0 0 0 0 0 -0.0977234577952012 P41920 0.9454690217971802 0.9559720158576964 0.11204519867897034 0.0042895092628896245 38.5679078866894 35.0 1.0 no 1826 chrIV_453254r 5612 essential YDR002W 212 - TCTTAACATCTACCTTTTCC K|77|N silent|AAG>AAA|K|77 V|76|L V|76|I YRB1 Yeast Ran Binder 201.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.8089255403797997 P41920 0.9173640012741088 0.9449430108070374 0.9525229930877686 0.0037734117358922963 0.04804385825991631 0.3167361617088318 -0.2392099946737289 -0.2342739999294281 -0.11512800306081772 45.96204081506278 35.0 1.0 no 1827 chrIV_453343r 5616 essential YDR002W 301 - ACCTCTTTCTTTCCATTCCT G|107|R G|107|S G|107|A G|107|D YRB1 Yeast Ran Binder 201.0 0 0 0 0 -1.4407967454352455 P41920 0.8943480253219604 0.9106770157814026 0.9094370007514954 0.8989760279655457 0.0 0.0 0.0 0.0 15.203455924987793 7.07668399810791 4.817302227020264 11.348261833190918 55.46804244530893 40.0 1.0 no 1828 chrIV_453486r 5618 essential YDR002W 444 - GATCTATCAGAACCAACGTT R|154|T R|154|K YRB1 Yeast Ran Binder 201.0 0 0 0 0 -0.7386431268859324 P41920 0.922694981098175 0.9502609968185424 0.003702004672959447 0.2454299628734589 2.315246105194092 -0.05958399921655655 43.32663515904125 40.0 1.0 no 1829 chrIV_453490 5619 essential YDR002W 445 + ACGTTGGTTCTGATAGATCT N|149|K silent|AAC>AAT|N|149 YRB1 Yeast Ran Binder 201.0 0 1 0 0 0.7504793706469144 P41920 0.9253829717636108 0.003451414639130235 -0.3907420039176941 46.47501752713328 40.0 1.0 no 1830 chrIV_473372 5623 essential YDR013W 215 + TTTCGTTACCTTGTTATGTA F|73|L silent|TTC>TTT|F|73 PSF1 Partner of Sld Five 208.0 0 0 0 0 0.2918119639061192 Q12488 0.9387490153312684 1.0 44.76016198376732 30.0 1.0 no 1831 chrIV_473380r 5624 essential YDR013W 226 - GTTCCTTTCCATACATAACA R|81|S silent|AGG>AGA|R|81 R|81|T R|81|K PSF1 Partner of Sld Five 208.0 0 0 0 0 -0.0653786882078603 Q12488 0.9087679982185364 0.932735025882721 0.955805003643036 0.009988895617425442 0.01094770524650812 0.05906863883137702 46.191225468351256 35.0 1.0 no 1832 chrIV_473435 5628 essential YDR013W 278 + AACAGACATACTAGATTCTA T|94|R T|94|I D|95|E silent|GAC>GAT|D|95 PSF1 Partner of Sld Five 208.0 0 0 0 0 0.8479745048294522 Q12488 0.9476869702339172 0.9472420215606691 0.9532920122146606 0.07498335838317871 0.4266321361064911 0.6291810274124146 37.36299802379557 30.0 1.0 no 1833 chrIV_480219 5637 high_effect YDR017C 2029 - TTCGCCATCATCTCTAGAAT E|683|Q E|683|K G|682|A G|682|D KCS1 pKC1 Suppressor 1050.0 0 0 0 0 -0.5853010389737902 Q12494 0.956179976463318 0.9475290179252625 0.9499930143356324 0.9446240067481996 0.5415653586387634 0.8694791793823242 0.5271756052970886 0.2231881767511368 47.58331370925083 40.0 0.0 no 1834 chrIV_480554r 5641 high_effect YDR017C 1691 + AAACTCTAATACGACTACAA N|565|K silent|AAC>AAT|N|565 S|566|C S|566|F KCS1 pKC1 Suppressor 1050.0 0 1 0 0 -0.13519265505784858 Q12494 0.9439849853515624 0.945252001285553 0.9294660091400146 1.0 0.05622130259871483 0.07610621303319931 34.63443265377037 30.0 0.0 no 1835 chrIV_480924 5652 high_effect YDR017C 1324 - CGACGAATGTTCCAAGGGGA silent|TCG>TCC|S|447 silent|TCG>TCA|S|447 KCS1 pKC1 Suppressor 1050.0 0 0 0 0 -0.08506315044504872 Q12494 48.45272145378237 55.00000000000001 0.0 no 1836 chrIV_480935r 5653 high_effect YDR017C 1310 + ACACATACATTCCTTCCCCT H|438|Q silent|CAC>CAT|H|438 H|438|D H|438|Y KCS1 pKC1 Suppressor 1050.0 0 1 0 0 -0.015188663536201132 Q12494 0.9588389992713928 0.9473130106925964 0.9489949941635132 0.06293206661939621 0.05418085306882858 0.3510105609893799 55.06097538323246 45.0 0.0 no 1837 chrIV_480969r 5654 high_effect YDR017C 1276 + CGCTTAATACAGAACCCACG L|427|V L|427|F KCS1 pKC1 Suppressor 1050.0 0 0 0 0 0.5131455519197969 Q12494 0.9512209892272948 0.9587849974632264 0.5649403929710388 0.7055976986885071 45.9711121511312 50.0 0.0 no 1838 chrIV_480971r 5656 high_effect YDR017C 1274 + TGCGCTTAATACAGAACCCA A|426|G A|426|V L|427|V L|427|F KCS1 pKC1 Suppressor 1050.0 0 0 0 0 0.0367641688355787 Q12494 0.9484469890594482 0.9504740238189696 0.9512209892272948 0.9587849974632264 0.3506668508052826 0.2218495011329651 0.5649403929710388 0.7055976986885071 47.813078713164536 45.0 0.0 no 1839 chrIV_481120 5657 high_effect YDR017C 1128 - TTCAGGACACCAATATAACG silent|CTG>CTC|L|382 silent|CTG>CTA|L|382 KCS1 pKC1 Suppressor 1050.0 0 0 0 0 0.37477217593105466 Q12494 40.71337400502102 40.0 0.0 no 1840 chrIV_481676r 5666 high_effect YDR017C 569 + GAGCTTACATGGAATATCGG S|191|R silent|AGC>AGT|S|191 KCS1 pKC1 Suppressor 1050.0 0 0 0 0 0.2689301823528112 Q12494 0.9417110085487366 0.4390099346637726 43.59614872247277 45.0 0.0 no 1841 chrIV_481700r 5669 high_effect YDR017C 545 + TTCGCCTAAGTCCACTTATC S|183|W S|183|L P|184|A P|184|S KCS1 pKC1 Suppressor 1050.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.8257005032475668 Q12494 0.9288619756698608 0.9298099875450134 0.9562489986419678 0.9498909711837769 0.013715727254748344 0.15837888419628146 0.8092333674430847 0.7832311987876892 50.61913387973614 45.0 0.0 no 1842 chrIV_481729r 5671 high_effect YDR017C 516 + CCAATTCAGAATGTTGATGA P|173|R P|173|L Q|175|E Q|175|* KCS1 pKC1 Suppressor 1050.0 0 0 0 0 -0.4270185264491997 Q12494 0.9432820081710817 0.9430609941482544 0.9590039849281312 0.6171510219573975 0.3074340522289276 1.0 40.513593405976344 35.0 0.0 no 1843 chrIV_481848 5675 high_effect YDR017C 400 - TCTATGCGCCACGTGTTTAT R|140|T R|140|K silent|GCG>GCC|A|138 silent|GCG>GCA|A|138 KCS1 pKC1 Suppressor 1050.0 0 1 0 0 0.5089973260252831 Q12494 0.932735025882721 0.955805003643036 0.38247108459472656 0.8687059879302979 51.641596967127036 45.0 0.0 no 1844 chrIV_481886r 5677 high_effect YDR017C 359 + TTTCATTTTATCTAACCACG F|121|L silent|TTC>TTT|F|121 KCS1 pKC1 Suppressor 1050.0 0 1 0 0 -0.017148982972586442 Q12494 0.9387490153312684 0.8152137398719788 40.45447903830609 30.0 0.0 no 1845 chrIV_481976r 5679 high_effect YDR017C 269 + GTCAGAAGCAACTCCCAAAT S|91|* S|91|L KCS1 pKC1 Suppressor 1050.0 0 0 0 0 -2.6248729087984346 Q12494 0.9298099875450134 0.1967926174402237 46.37606100664277 45.0 0.0 yes 1846 chrIV_482043 5682 high_effect YDR017C 205 - ATCTACACCATTGTTGTTAT D|75|H D|75|N V|74|L V|74|I KCS1 pKC1 Suppressor 1050.0 0 0 0 0 -1.0158166795343515 Q12494 0.9486550092697144 0.956179976463318 0.9539830088615416 0.9574310183525084 0.13456663489341736 0.5344247221946716 0.8833350539207458 0.8863069415092468 44.074301092713604 30.0 0.0 no 1847 chrIV_482177 5683 high_effect YDR017C 71 - TGCACCCTTCCGACTCTTTT C|30|S C|30|Y silent|GGG>GGC|G|29 silent|GGG>GGA|G|29 KCS1 pKC1 Suppressor 1050.0 0 1 0 0 0.6401356893557729 Q12494 0.9421560168266296 0.9290120005607604 1.0 0.17100591957569122 57.078748578165566 50.0 0.0 no 1848 chrIV_482116r 5684 high_effect YDR017C 129 + AAACTTTCCTCCGTCTTACA L|45|V L|45|F KCS1 pKC1 Suppressor 1050.0 0 0 0 0 -0.19869984639866267 Q12494 0.9512209892272948 0.9587849974632264 0.07489185035228729 0.03836248070001602 48.32303663089516 40.0 0.0 no 1849 chrIV_482182r 5686 high_effect YDR017C 63 + TTGCGCCAAAAAGAGTCGGA R|23|G R|23|C silent|CGC>CGG|R|23 silent|CGC>CGT|R|23 KCS1 pKC1 Suppressor 1050.0 0 1 0 0 -0.2472637997669984 Q12494 0.8994590044021606 0.8926740288734436 46.50109672975759 50.0 0.0 no 1850 chrIV_486938 5689 essential YDR021W 134 + ACCATCCTCTATCCAATCAA P|46|R P|46|L P|46|A P|46|S FAL1 eukaryotic translation initiation factor Four A Like 399.0 0 0 0 0 -3.0039125018445025 Q12099 0.0 0.0 0.0 0.0 48.906552304540526 40.0 1.0 yes 1851 chrIV_486959 5693 essential YDR021W 155 + GGCTATTACACAGATTATTT A|53|G A|53|V FAL1 eukaryotic translation initiation factor Four A Like 399.0 0 0 0 0 -1.102084503959547 Q12099 0.1834174990653992 0.0050322283059358605 41.17305707134955 30.0 1.0 no 1852 chrIV_486960 5694 essential YDR021W 156 + GCTATTACACAGATTATTTC A|53|G A|53|V FAL1 eukaryotic translation initiation factor Four A Like 399.0 0 0 0 0 -0.07934237201080838 Q12099 0.1834174990653992 0.0050322283059358605 39.62957342193408 30.0 1.0 no 1853 chrIV_487098r 5696 essential YDR021W 297 - TGGCTTGCTAATTCACGTGT S|105|T S|105|N FAL1 eukaryotic translation initiation factor Four A Like 399.0 0 0 0 0 -0.4777556448410884 Q12099 0.5748026371002197 0.4934380352497101 50.03943470945819 45.0 1.0 no 1854 chrIV_487237r 5699 essential YDR021W 436 - TCTTCCTGGTGTTCCGCTAA R|152|T R|152|K G|151|A G|151|E FAL1 eukaryotic translation initiation factor Four A Like 399.0 0 0 0 0 -5.2032044894759295 Q12099 0.0041700899600982675 0.1134847104549408 0.011347777210175993 0.0018717923667281864 56.20729651938183 50.0 1.0 yes 1855 chrIV_487392r 5700 essential YDR021W 591 - ACAACAACTTGGCAATTTTT V|204|L V|204|I V|203|L V|203|I FAL1 eukaryotic translation initiation factor Four A Like 399.0 0 0 0 0 0.6808127804583788 Q12099 1.0 0.07985135167837143 0.2159203141927719 0.35773828625679016 39.45081188830977 30.0 1.0 no 1856 chrIV_487415 5701 essential YDR021W 611 + TGTCAGCGCAACAATGAATA silent|GTC>GTG|V|205 silent|GTC>GTT|V|205 S|206|R silent|AGC>AGT|S|206 FAL1 eukaryotic translation initiation factor Four A Like 399.0 0 0 0 0 -0.4908897064913044 Q12099 0.0009884468745440245 41.99553443617805 40.0 1.0 no 1857 chrIV_487403r 5702 essential YDR021W 602 - TTGCGCTGACAACAACAACT A|207|P A|207|T S|206|T S|206|N FAL1 eukaryotic translation initiation factor Four A Like 399.0 0 0 0 0 -0.5017108933847523 Q12099 0.0 0.0 0.050832781940698624 0.0028107510879635807 44.07539178431733 45.0 1.0 no 1858 chrIV_489519 5704 essential YDR023W 11 + CAACCAATTTATCGAAGATA N|5|K silent|AAC>AAT|N|5 Q|6|E Q|6|* SES1 SEryl-tRNA Synthetase 462.0 0 0 0 0 0.8779436378935347 P07284 0.9470080137252808 1.0217000246047974 0.5411183834075928 0.988109290599823 36.609990356854894 30.0 1.0 no 1859 chrIV_489758r 5708 essential YDR023W 253 - AGTCAATTCCTTCTTTTGTT L|90|F silent|TTG>TTA|L|90 SES1 SEryl-tRNA Synthetase 462.0 0 1 0 0 0.22174856045443608 P07284 0.9792410135269164 0.1220754012465477 0.5689600110054016 46.235240182721384 30.0 1.0 no 1860 chrIV_489878 5709 essential YDR023W 370 + ACAATGAATTGGTCCGTACT N|124|K silent|AAC>AAT|N|124 SES1 SEryl-tRNA Synthetase 462.0 0 1 0 0 0.9290028994838924 P07284 0.9080389738082886 0.06413602828979492 44.60598884005435 40.0 1.0 no 1861 chrIV_490255 5716 essential YDR023W 747 + CCTATCTCCGCTTACCACAG P|250|R P|250|L I|251|M silent|ATC>ATT|I|251 SES1 SEryl-tRNA Synthetase 462.0 0 0 0 0 -3.940771193775017 P07284 0.5625730156898499 0.5615760087966919 0.8614590167999268 0.0026429828722029924 0.007431429345160724 0.06458022445440292 55.34041507283258 55.00000000000001 1.0 yes 1862 chrIV_490262r 5719 essential YDR023W 757 - CCATTCACCGCTGTGGTAAG W|259|S W|259|* E|258|Q E|258|K SES1 SEryl-tRNA Synthetase 462.0 0 0 0 0 -1.7918296100442324 P07284 0.7494590282440186 0.8205609917640686 0.7931060194969177 0.1299726366996765 0.09169312566518784 0.08220819383859634 2.7350800037384038 53.003877273804854 55.00000000000001 1.0 no 1863 chrIV_490269r 5720 essential YDR023W 764 - TTTCAAACCATTCACCGCTG E|261|Q E|261|K SES1 SEryl-tRNA Synthetase 462.0 0 0 0 0 0.09274760048362274 P07284 0.9374030232429504 0.9066100120544434 0.6854804754257202 0.6221363544464111 47.83939992145707 45.0 1.0 no 1864 chrIV_490432r 5728 essential YDR023W 927 - AACTCCTCCCAAGATTTTTC E|315|D silent|GAG>GAA|E|315 E|315|Q E|315|K SES1 SEryl-tRNA Synthetase 462.0 0 1 0 0 0.5970487067763564 P07284 0.8076189756393433 0.8584929704666138 0.7646610140800476 0.23216837644577026 0.3794408440589905 0.3330783843994141 48.2825466290023 40.0 1.0 no 1865 chrIV_495618r 5733 high_effect YDR027C 1678 + AAGCTCTTCGAAGACTTTAT A|561|G A|561|V L|562|V L|562|F VPS54 Vacuolar Protein Sorting 889.0 0 0 0 0 0.11023506518991 Q12071 0.9484469890594482 0.9504740238189696 0.9512209892272948 0.9587849974632264 0.3210133910179138 0.0712863877415657 0.05540885403752327 0.1660488247871399 41.73745989273625 35.0 0.0 no 1866 chrIV_495876 5734 high_effect YDR027C 1423 - ATTCAATCTGACTATTAATT L|480|F silent|TTG>TTA|L|480 VPS54 Vacuolar Protein Sorting 889.0 0 0 0 0 0.8869031193396171 Q12071 0.9587849974632264 0.0 34.52456608244461 20.0 0.0 no 1867 chrIV_496362 5746 high_effect YDR027C 937 - TCTTATATTCTCTGCGTCAA R|319|T R|319|K VPS54 Vacuolar Protein Sorting 889.0 0 0 0 0 1.1948364347927036 Q12071 0.932735025882721 0.955805003643036 0.4744517207145691 0.4920668005943298 45.24175848051442 35.0 0.0 no 1868 chrIV_496962 5752 high_effect YDR027C 337 - GTTCATCACAATTTCATAGA M|118|I M|118|I silent|GTG>GTC|V|117 silent|GTG>GTA|V|117 VPS54 Vacuolar Protein Sorting 889.0 0 0 0 0 0.930561167758538 Q12071 0.9553959965705872 0.9553959965705872 0.2405977100133896 0.2405977100133896 40.19125625469394 30.0 0.0 no 1869 chrIV_496993r 5753 high_effect YDR027C 303 + TCCATGGACTTTTCGCCATT silent|TCC>TCG|S|102 silent|TCC>TCT|S|102 S|102|C S|102|F VPS54 Vacuolar Protein Sorting 889.0 0 0 0 0 0.2344745909172876 Q12071 0.945252001285553 0.9294660091400146 0.08031663298606873 0.07038121670484543 53.01266027686813 45.0 0.0 no 1870 chrIV_497119 5755 high_effect YDR027C 180 - CTCGAAGATCTTCTCGCTCT silent|TCG>TCC|S|66 silent|TCG>TCA|S|66 VPS54 Vacuolar Protein Sorting 889.0 0 0 0 0 -0.7034729702264422 Q12071 50.60938453520896 50.0 0.0 no 1871 chrIV_497160 5756 high_effect YDR027C 139 - ACTTAACAAGTCGTCATTAA S|53|T S|53|N L|51|F silent|TTG>TTA|L|51 VPS54 Vacuolar Protein Sorting 889.0 0 0 0 0 0.007974426093185756 Q12071 0.9512869715690612 0.9536849856376648 0.9587849974632264 0.0 0.0 0.037689831107854836 37.94568279155982 30.0 0.0 no 1872 chrIV_497152r 5757 high_effect YDR027C 144 + GACGACTTGTTAAGTATATC D|49|E silent|GAC>GAT|D|49 D|50|E silent|GAC>GAT|D|50 VPS54 Vacuolar Protein Sorting 889.0 0 0 0 0 -0.732233067520081 Q12071 0.9532920122146606 0.9532920122146606 0.0 0.2959059476852417 38.936324760265215 35.0 0.0 no 1873 chrIV_497209 5758 high_effect YDR027C 90 - CCACTATCACTATTACGAGA S|36|T S|36|N G|37|R G|37|S VPS54 Vacuolar Protein Sorting 889.0 0 1 0 0 -0.43068516873515217 Q12071 0.9512869715690612 0.9536849856376648 0.941340982913971 0.951104998588562 0.4522115886211395 0.3484531342983246 0.4533863365650177 0.8320217728614807 43.9851681569769 40.0 0.0 no 1874 chrIV_497236r 5761 high_effect YDR027C 60 + CCTAAAATTGTTGTTCCTGA P|21|R P|21|L VPS54 Vacuolar Protein Sorting 889.0 0 0 0 0 0.7047735813297586 Q12071 0.9432820081710817 0.9430609941482544 43.485757704725636 35.0 0.0 no 1875 chrIV_497237r 5762 high_effect YDR027C 59 + TCCTAAAATTGTTGTTCCTG P|21|R P|21|L P|21|A P|21|S VPS54 Vacuolar Protein Sorting 889.0 0 0 0 0 0.7864231259187159 Q12071 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 43.24970122959138 35.0 0.0 no 1876 chrIV_497281r 5765 high_effect YDR027C 15 + ACACCTCATAATAAAAGCCA P|7|A P|7|S T|6|R T|6|I VPS54 Vacuolar Protein Sorting 889.0 0 1 0 0 -0.7894315419237322 Q12071 0.9562489986419678 0.9498909711837769 0.9476869702339172 0.9472420215606691 41.42045178202824 35.0 0.0 no 1877 chrIV_525489 5768 essential YDR037W 49 + TACATCTCGACGAAGCTACC H|18|D H|18|Y L|19|V L|19|F KRS1 Lysyl (K) tRNA Synthetase 591.0 0 0 0 0 -1.9056505998627915 P15180 0.9473130106925964 0.9489949941635132 0.9512209892272948 0.9587849974632264 0.2013306170701981 1.0 0.2790985703468323 0.16488927602767944 47.11950970499731 50.0 1.0 no 1878 chrIV_525490 5769 essential YDR037W 50 + ACATCTCGACGAAGCTACCG H|18|D H|18|Y L|19|V L|19|F KRS1 Lysyl (K) tRNA Synthetase 591.0 0 0 0 0 0.13102333796686902 P15180 0.9473130106925964 0.9489949941635132 0.9512209892272948 0.9587849974632264 0.2013306170701981 1.0 0.2790985703468323 0.16488927602767944 48.60946876265109 55.00000000000001 1.0 no 1879 chrIV_525522r 5771 essential YDR037W 85 - ACGCTTCTTCAATTCAGACT K|34|N silent|AAG>AAA|K|34 R|35|P R|35|H KRS1 Lysyl (K) tRNA Synthetase 591.0 0 1 0 0 -0.4619854911827879 P15180 0.9355990290641784 0.9099509716033936 0.9570810198783876 0.1875233501195908 0.07333473116159439 0.031313717365264886 0.2912000119686127 46.57763075335208 40.0 1.0 no 1880 chrIV_525895 5782 essential YDR037W 455 + TCAATTGATGTCCCAATTGC Q|153|E Q|153|* KRS1 Lysyl (K) tRNA Synthetase 591.0 0 0 0 0 -0.7251786865687699 P15180 0.9590039849281312 0.0 46.27845383959965 40.0 1.0 no 1881 chrIV_525925 5784 essential YDR037W 485 + CGACCCAGACTCTTACGAAA D|163|E silent|GAC>GAT|D|163 P|164|A P|164|S KRS1 Lysyl (K) tRNA Synthetase 591.0 0 0 0 0 -2.223623574971046 P15180 0.9532920122146606 0.9562489986419678 0.9498909711837769 0.8428782820701599 0.22780779004096985 0.1716039627790451 46.70925283261346 50.0 1.0 yes 1882 chrIV_525928r 5785 essential YDR037W 491 - GATCCTTTTCGTAAGAGTCT D|170|H D|170|N K|169|N silent|AAG>AAA|K|169 KRS1 Lysyl (K) tRNA Synthetase 591.0 0 0 0 0 -0.25319943603321704 P15180 0.9486550092697144 0.956179976463318 0.9355990290641784 0.5360338091850281 0.3071538805961609 0.2353521585464477 47.299135945361 40.0 1.0 no 1883 chrIV_526007 5786 essential YDR037W 567 + CAACCAAAGAAAGGTGGTGA P|191|A P|191|S P|191|R P|191|L KRS1 Lysyl (K) tRNA Synthetase 591.0 0 0 0 0 -1.266287382942639 P15180 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.0 0.0 0.0 0.0 41.25009411611279 45.0 1.0 no 1884 chrIV_526010r 5787 essential YDR037W 573 - TCACCTTCACCACCTTTCTT G|197|A G|197|D E|198|Q E|198|K KRS1 Lysyl (K) tRNA Synthetase 591.0 0 0 0 0 -2.6046213259840747 P15180 0.9499930143356324 0.9446240067481996 0.956179976463318 0.9475290179252625 0.02665484882891178 0.006182712968438864 0.04546291008591652 0.0049913832917809495 55.56257881734661 45.0 1.0 yes 1885 chrIV_526038r 5788 essential YDR037W 601 - TTGCACTCTGCTAACGAAGA silent|GTG>GTC|V|206 silent|GTG>GTA|V|206 V|206|L V|206|M KRS1 Lysyl (K) tRNA Synthetase 591.0 0 0 0 0 -0.13370690725733825 P15180 0.9539830088615416 0.9587630033493042 0.7146620750427246 0.28193241357803345 45.49763457178898 45.0 1.0 no 1886 chrIV_526114r 5793 essential YDR037W 677 - GCTTTCTGTATCTGGTTTCC K|232|N silent|AAG>AAA|K|232 R|231|T R|231|K KRS1 Lysyl (K) tRNA Synthetase 591.0 0 0 0 0 -0.6632238364214813 P15180 0.9355990290641784 0.932735025882721 0.955805003643036 0.12392137199640275 0.004402453079819679 0.06817799806594849 54.03558964677797 45.0 1.0 no 1887 chrIV_526201 5795 essential YDR037W 761 + CCGTTACATCAGAAGATTTT R|255|G R|255|C Y|256|* silent|TAC>TAT|Y|256 KRS1 Lysyl (K) tRNA Synthetase 591.0 0 0 0 0 0.4801411064434009 P15180 0.8994590044021606 0.8926740288734436 0.329350620508194 0.036442551761865616 42.44597117564837 35.0 1.0 no 1888 chrIV_526201r 5796 essential YDR037W 764 - CCAAAAATCTTCTGATGTAA L|261|F silent|TTG>TTA|L|261 KRS1 Lysyl (K) tRNA Synthetase 591.0 0 1 0 0 -0.1183746114277516 P15180 0.9587849974632264 0.0952482596039772 36.567637581616744 30.0 1.0 no 1889 chrIV_526225r 5797 essential YDR037W 788 - CTACTTCAATAAACTTTCTT V|269|L V|269|I E|268|Q E|268|K KRS1 Lysyl (K) tRNA Synthetase 591.0 0 1 0 0 -0.2914330179795605 P15180 0.9539830088615416 0.9574310183525084 0.956179976463318 0.9475290179252625 0.014447541907429697 0.21003372967243195 0.04461285471916199 0.004892284516245128 0.8312000036239624 0.6119999885559082 36.238431441782666 25.0 1.0 no 1890 chrIV_526306r 5801 essential YDR037W 869 - TGTCCATATCAAGGTCATTA D|296|H D|296|N M|295|I M|295|I KRS1 Lysyl (K) tRNA Synthetase 591.0 0 0 0 0 -1.0820438274890027 P15180 0.9486550092697144 0.956179976463318 0.9553959965705872 0.9553959965705872 0.014903943985700609 0.2687802016735077 0.14647309482097626 0.14647309482097626 0.5925999879837036 0.5925999879837036 45.10320279297793 35.0 1.0 no 1891 chrIV_526586r 5807 essential YDR037W 1149 - TTCAATTCTAGTTCTTTGGC L|389|F silent|TTG>TTA|L|389 KRS1 Lysyl (K) tRNA Synthetase 591.0 0 0 0 0 -0.129571791927584 P15180 0.9587849974632264 0.009356901049613951 3.5357999801635738 45.018941443201015 35.0 1.0 no 1892 chrIV_526661 5808 essential YDR037W 1221 + TTCAACGTTAAGTTCCCATC F|408|L silent|TTC>TTT|F|408 N|409|K silent|AAC>AAT|N|409 KRS1 Lysyl (K) tRNA Synthetase 591.0 0 1 0 0 -0.5326269244490015 P15180 0.9387490153312684 0.9439849853515624 1.0 0.1985003650188446 1.22979998588562 46.4169459460748 40.0 1.0 no 1893 chrIV_539857r 5812 essential YDR041W 57 - GCCTCTACATTTACAGGATA E|25|D silent|GAG>GAA|E|25 A|26|P A|26|T RSM10 Ribosomal Small subunit of Mitochondria 203.0 0 0 0 0 0.07376319067251913 Q03201 0.94931298494339 0.9573720097541808 0.9523990154266356 0.4061613976955414 0.17291705310344696 0.2646945118904114 47.45000790629223 40.0 1.0 no 1894 chrIV_539977 5813 essential YDR041W 174 + TCAGACTTCATACTTAGAAC S|59|* S|59|L D|60|E silent|GAC>GAT|D|60 RSM10 Ribosomal Small subunit of Mitochondria 203.0 0 0 0 0 -1.3181064776670173 Q03201 0.9298099875450134 0.9532920122146606 0.058298002928495414 0.01885068975389004 39.055043892202384 35.0 1.0 no 1895 chrIV_540117 5817 essential YDR041W 314 + TACACATAAGAGGCTCATTA T|106|R T|106|I H|107|D H|107|Y RSM10 Ribosomal Small subunit of Mitochondria 203.0 0 0 0 0 0.009263719974184098 Q03201 0.9476869702339172 0.9472420215606691 0.9473130106925964 0.9489949941635132 0.0 0.0 0.11546776443719865 0.7415404915809631 41.29131696583289 35.0 1.0 no 1896 chrIV_540153r 5819 essential YDR041W 353 - TCAACATCTGTAGCACTTCG L|124|F silent|TTG>TTA|L|124 M|123|I M|123|I RSM10 Ribosomal Small subunit of Mitochondria 203.0 0 0 0 0 0.13540793870848952 Q03201 0.9587849974632264 0.9553959965705872 0.9553959965705872 0.6159214377403259 0.8912340402603149 0.8912340402603149 46.30800488008339 45.0 1.0 no 1897 chrIV_540155r 5821 essential YDR041W 355 - TATCAACATCTGTAGCACTT L|124|F silent|TTG>TTA|L|124 M|123|I M|123|I RSM10 Ribosomal Small subunit of Mitochondria 203.0 0 0 0 0 0.11820363406007532 Q03201 0.9587849974632264 0.9553959965705872 0.9553959965705872 0.6159214377403259 0.8912340402603149 0.8912340402603149 43.483114324423696 35.0 1.0 no 1898 chrIV_540180 5822 essential YDR041W 377 + TTACATTACGAAGCACTCTA Y|127|* silent|TAC>TAT|Y|127 RSM10 Ribosomal Small subunit of Mitochondria 203.0 0 0 0 0 -0.2408880014376329 Q03201 41.400290611411094 35.0 1.0 no 1899 chrIV_540190 5823 essential YDR041W 387 + AAGCACTCTATGGCAGGCGT H|131|D H|131|Y H|131|Q silent|CAC>CAT|H|131 RSM10 Ribosomal Small subunit of Mitochondria 203.0 0 0 0 0 -2.7528143032682526 Q03201 0.9473130106925964 0.9489949941635132 0.9588389992713928 0.10268756747245787 0.7094427943229675 0.11293590813875197 54.51496238154891 55.00000000000001 1.0 yes 1900 chrIV_546668 5827 essential YDR044W 26 + TCTTCCAATTAGACAACAAA L|10|V L|10|F P|11|A P|11|S HEM13 HEMe biosynthesis 328.0 0 0 0 0 0.6299425706351982 P11353 0.9512209892272948 0.9587849974632264 0.9562489986419678 0.9498909711837769 0.2767958343029022 0.05551772192120552 0.08030858635902405 0.17518554627895355 1.6259479522705078 0.0444520004093647 1.7605240345001218 1.8837080001831052 1.5373799800872805 0.3657400012016296 37.43005208039216 30.0 1.0 no 1901 chrIV_546672r 5828 essential YDR044W 33 - GCTTCCATTTGTTGTCTAAT A|18|P A|18|T E|17|Q E|17|K HEM13 HEMe biosynthesis 328.0 0 0 0 0 1.0604294531184866 P11353 0.9573720097541808 0.9523990154266356 0.956179976463318 0.9475290179252625 0.33337247371673584 0.7087892889976501 0.33675509691238403 0.36659500002861023 3.607943058013916 1.0602359771728516 -0.29449400305747986 0.02365799993276596 5.0864601135253915 0.3657400012016296 47.788666569689724 35.0 1.0 no 1902 chrIV_546708 5829 essential YDR044W 66 + AAACAAGCTGAAATCACGCA Q|24|E Q|24|* HEM13 HEMe biosynthesis 328.0 0 0 0 0 0.5547906961902997 P11353 0.9590039849281312 0.0 1.0496020317077637 39.744624575359246 40.0 1.0 no 1903 chrIV_546713 5830 essential YDR044W 71 + AGCTGAAATCACGCAAGGTT A|25|G A|25|V HEM13 HEMe biosynthesis 328.0 0 0 0 0 -0.28156080957533264 P11353 0.9484469890594482 0.9504740238189696 0.3795758783817291 0.2895732522010803 0.6025639772415161 0.3579300045967102 0.679099977016449 0.1827400028705597 45.52035582933587 45.0 1.0 no 1904 chrIV_546775r 5834 essential YDR044W 136 - ACCACCACCATCGTTACCAC G|52|R G|52|S G|52|A G|52|D HEM13 HEMe biosynthesis 328.0 0 0 0 0 -1.3156725689651911 P11353 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.18791091442108154 0.270091325044632 0.2208805233240128 0.09541736543178557 0.5153260231018066 0.32976800203323364 0.6997140049934387 0.6412339806556702 9.676480293273926 8.80735969543457 4.941299915313722 11.119359970092773 55.592014017473495 55.00000000000001 1.0 no 1905 chrIV_546801 5835 essential YDR044W 159 + ACCTCTATGGTTATCCAAGA silent|ACC>ACG|T|54 silent|ACC>ACT|T|54 T|54|S T|54|I HEM13 HEMe biosynthesis 328.0 0 0 0 0 -0.3461112364406522 P11353 0.9491789937019348 0.9472420215606691 0.6158350706100464 1.0 0.024469999596476555 -0.14479200541973114 48.113107495655186 40.0 1.0 no 1906 chrIV_546886r 5840 essential YDR044W 247 - ATCAGCTTTCATGGCTGAAA D|89|H D|89|N A|88|P A|88|T HEM13 HEMe biosynthesis 328.0 0 0 0 0 -0.2582719545945201 P11353 0.9486550092697144 0.956179976463318 0.9573720097541808 0.9523990154266356 0.14084698259830475 0.6458383798599243 0.08856633305549623 0.24929179251194 -0.15722599625587466 -0.1801140010356903 0.5249699950218201 0.011744000017642977 -0.494599997997284 0.34404000639915466 2.369140148162842 1.2978299856185913 -0.6411399841308594 0.9544000029563904 45.88719753377268 40.0 1.0 no 1907 chrIV_546927r 5842 essential YDR044W 288 - AAACCAGTCTTTGGATCTTC G|102|A G|102|D G|102|R G|102|S HEM13 HEMe biosynthesis 328.0 0 1 0 0 0.8320875895827005 P11353 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.7601534724235535 0.6619195342063904 0.5112080574035645 0.7342483401298523 45.358075845662825 40.0 1.0 no 1908 chrIV_547039 5846 essential YDR044W 397 + ACTACCGTTACTTCGAAACT N|133|K silent|AAC>AAT|N|133 Y|134|* silent|TAC>TAT|Y|134 HEM13 HEMe biosynthesis 328.0 0 1 0 0 -1.773419519847054 P11353 0.9439849853515624 0.0 -0.5837699770927429 0.5119900107383728 43.924897216417094 40.0 1.0 no 1909 chrIV_547154 5853 essential YDR044W 512 + CCAACTGCACAAGGATGCCT Q|172|E Q|172|* L|173|V silent|CTG>TTG|L|173 HEM13 HEMe biosynthesis 328.0 0 0 0 0 0.7149154959840662 P11353 0.9590039849281312 0.9512209892272948 0.6871470808982849 0.3273989260196686 0.28653401136398315 0.24145400524139404 0.11828000098466873 52.65309534399745 55.00000000000001 1.0 no 1910 chrIV_548047r 5860 essential YDR045C 241 + ACTTTTTCCAACTACAAATT Y|81|* silent|TAC>TAT|Y|81 RPC11 RNA Polymerase C 110.0 0 0 0 0 0.7387037186937959 Q04307 38.23784563896618 25.0 0.0 no 1911 chrIV_548081 5861 essential YDR045C 210 - CCACCACAAGTATCATAATT G|76|A G|76|D G|77|R G|77|S RPC11 RNA Polymerase C 110.0 0 0 0 0 -1.0542454253573204 Q04307 0.4709480702877045 0.7896736264228821 0.14943470060825348 0.4639556407928467 42.831710473186824 35.0 0.0 no 1912 chrIV_548084r 5863 essential YDR045C 204 + TGTCCCAATTATGATACTTG P|70|A P|70|S P|70|R P|70|L RPC11 RNA Polymerase C 110.0 0 0 0 0 -0.5332567847322731 Q04307 0.18043074011802676 0.02571223303675652 0.0071503291837871075 0.016626816242933273 43.119144658467924 35.0 0.0 no 1913 chrIV_548080 5864 essential YDR045C 211 - ACCACCACAAGTATCATAAT G|77|R G|77|S G|77|A G|77|D RPC11 RNA Polymerase C 110.0 0 0 0 0 -0.6546746699018976 Q04307 0.14943470060825348 0.4639556407928467 0.20777077972888947 0.8110140562057495 43.007384478684465 35.0 0.0 no 1914 chrIV_548201 5865 essential YDR045C 90 - CCCTCTATAGGAAACTCATA E|36|D silent|GAG>GAA|E|36 G|37|R G|37|S RPC11 RNA Polymerase C 110.0 0 0 0 0 -2.3000931303725625 Q04307 0.6295697093009949 0.9846054315567015 0.7404835820198059 45.03761156677598 40.0 0.0 yes 1915 chrIV_548201r 5866 essential YDR045C 87 + CCATATGAGTTTCCTATAGA P|30|R P|30|L RPC11 RNA Polymerase C 110.0 0 0 0 0 0.7115832681237646 Q04307 0.0023828139528632164 0.003228286514058709 44.946844286008165 35.0 0.0 no 1916 chrIV_552049 5877 essential YDR047W 189 + CAGCCGGTAAGACGCTATAG P|65|A P|65|S P|65|R P|65|L HEM12 HEMe biosynthesis 362.0 0 0 0 0 -1.7643426184595865 P32347 0.0 0.0 0.0 0.0 49.237487259649974 55.00000000000001 1.0 no 1917 chrIV_552198 5885 essential YDR047W 338 + CCAAACGGTATTAGACTACA Q|114|E Q|114|* T|115|R T|115|M HEM12 HEMe biosynthesis 362.0 0 0 0 0 0.2064389289528838 P32347 1.0 1.0 0.03643303364515305 42.04501116353497 40.0 1.0 no 1918 chrIV_552251 5887 essential YDR047W 391 + TCAAGGCAATCACCATGACA F|131|L silent|TTC>TTT|F|131 A|133|G A|133|V HEM12 HEMe biosynthesis 362.0 0 0 0 0 -0.07940414854399773 P32347 0.4676016271114349 0.0475546158850193 0.003939111251384021 -2.5448598861694336 46.65270741340942 45.0 1.0 no 1919 chrIV_552324 5890 essential YDR047W 464 + GACTCTAATGGTTTATATGA T|156|S T|156|I L|157|V silent|CTA>TTA|L|157 HEM12 HEMe biosynthesis 362.0 0 0 0 0 0.028440023290950182 P32347 0.02113189548254013 0.0021580047905445103 0.012981520034372808 38.83262225668051 30.0 1.0 no 1920 chrIV_552443r 5891 essential YDR047W 586 - TTGCTGACTCAGAAACTCCA Q|201|H silent|CAG>CAA|Q|201 HEM12 HEMe biosynthesis 362.0 0 0 0 0 -0.2485982446977191 P32347 0.13705666363239288 47.2933634628875 45.0 1.0 no 1921 chrIV_555955 5899 essential YDR050C 498 - CCGGTACCAATGGCCCAGAC G|173|R G|173|S G|171|A G|171|D TPI1 Triose-Phosphate Isomerase 248.0 0 0 0 0 -0.8179337177796726 P00942 0.0 0.0 0.0 0.0 3.5325200557708736 4.054920196533203 2.287800073623657 2.2700400352478027 58.05179964619418 65.0 0.0 no 1922 chrIV_555968r 5901 essential YDR050C 482 + TGTCGCTTACGAACCAGTCT silent|GTC>GTG|V|162 silent|GTC>GTT|V|162 A|163|G A|163|V TPI1 Triose-Phosphate Isomerase 248.0 0 0 0 1 -0.16786418489423702 P00942 0.04761789739131928 0.0032211977522820234 1.698799967765808 -1.0687799453735352 51.28478085888617 50.0 0.0 no 1923 chrIV_556044 5904 essential YDR050C 409 - AACAACATCCAAAGTCTTAC V|143|L V|143|I V|142|L V|142|I TPI1 Triose-Phosphate Isomerase 248.0 0 1 0 0 0.16466973348542602 P00942 0.2975345551967621 0.4375834465026856 0.016808001324534416 0.07948616147041321 -0.6354799866676331 0.3670400083065033 0.08058000355958939 -0.23499999940395355 -0.07791999727487564 -0.4230599999427795 38.69915697937552 35.0 0.0 no 1924 chrIV_556113 5908 essential YDR050C 340 - ACCTTGACCTAAAGCGAACT G|120|R G|120|S G|120|A G|120|D TPI1 Triose-Phosphate Isomerase 248.0 0 0 0 0 0.06350594294652362 P00942 0.004276807885617018 0.011119239032268524 0.005782401654869318 0.018809961155056957 3.580319881439209 3.94163990020752 3.2405600547790527 4.12116003036499 46.03363827220358 45.0 0.0 no 1925 chrIV_556208 5912 essential YDR050C 245 - TAGCACCAACATCCTTGATT A|88|P A|88|T G|87|A G|87|D TPI1 Triose-Phosphate Isomerase 248.0 0 1 0 0 -0.9686997925283404 P00942 0.004989672917872667 0.024880224838852882 0.01512190140783787 0.2168877273797989 4.132040023803712 3.857439994812012 4.064899921417236 4.9360198974609375 3.970380067825317 1.2039999961853027 47.7879786727121 40.0 0.0 no 1926 chrIV_556215 5913 essential YDR050C 238 - AACATCCTTGATTTGGTCAA V|86|L V|86|I D|85|H D|85|N TPI1 Triose-Phosphate Isomerase 248.0 0 1 0 0 -0.7541285886817621 P00942 1.0 0.44100838899612427 0.003429221920669079 0.1620115041732788 -1.0137200355529783 -0.8289999961853027 -0.21216000616550448 -0.3280400037765503 -0.7821800112724304 -0.6632000207901001 -1.1733999252319336 -0.8145999908447266 3.4842000007629395 1.151600003242493 43.79336031805372 35.0 0.0 no 1927 chrIV_556355 5916 essential YDR050C 98 - TAACAACTTCGACATTTTCT V|39|L V|39|I V|38|L V|38|I TPI1 Triose-Phosphate Isomerase 248.0 0 0 0 0 0.3852543560633287 P00942 0.0251713115721941 0.021957326680421833 0.015426421537995337 0.1098986342549324 3.2732601165771484 1.5506600141525269 0.9491999745368958 -0.91729998588562 38.961109429830636 30.0 0.0 no 1928 chrIV_556395 5917 essential YDR050C 58 - TCTTTCAACAATTTCCTTAA R|26|T R|26|K E|25|Q E|25|K TPI1 Triose-Phosphate Isomerase 248.0 0 1 0 0 0.4328451439780256 P00942 0.7618038654327393 0.9439682960510254 0.5592008233070374 1.0 0.7863399982452393 0.2198999971151352 -0.03359999880194664 -0.10627999901771544 39.0851181238869 25.0 0.0 no 1929 chrIV_559319 5926 essential YDR052C 1287 - TCTTTTTCTTCTTTCAACGG E|436|Q E|436|K DBF4 DumbBell Former 704.0 0 1 0 0 0.02642272908100607 P32325 0.5340204238891602 0.7746645212173462 44.304124346145954 35.0 0.0 no 1930 chrIV_559483r 5927 essential YDR052C 1120 + CTACCAAGAGCTTCAAAAAA T|375|S T|375|I silent|ACC>ACG|T|375 silent|ACC>ACT|T|375 DBF4 DumbBell Former 704.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.6916435919047695 P32325 0.8160831928253174 0.23461806774139404 37.27030874634363 35.0 0.0 no 1931 chrIV_559327 5928 essential YDR052C 1279 - TTCTTTCAACGGAGGCTCTT E|433|Q E|433|K L|431|F silent|TTG>TTA|L|431 DBF4 DumbBell Former 704.0 0 0 0 0 -0.6442935576340489 P32325 0.4026702344417572 0.4690928757190704 0.07084622979164124 49.96396675099322 45.0 0.0 no 1932 chrIV_559555 5929 essential YDR052C 1051 - AACTGATGACGTATTCAGTA V|357|L V|357|I DBF4 DumbBell Former 704.0 0 1 0 0 0.2382492380278999 P32325 40.630128559265025 35.0 0.0 no 1933 chrIV_559693r 5931 essential YDR052C 910 + TCGGAAGATGCCCTTTTATA F|304|L silent|TTC>TTT|F|304 DBF4 DumbBell Former 704.0 0 0 0 0 0.02012518164452237 P32325 0.0 47.457901501666974 40.0 0.0 no 1934 chrIV_559694r 5932 essential YDR052C 909 + TTCGGAAGATGCCCTTTTAT F|304|L silent|TTC>TTT|F|304 DBF4 DumbBell Former 704.0 0 0 0 0 -0.5105694987540937 P32325 0.0 48.23577877307457 40.0 0.0 no 1935 chrIV_559721 5933 essential YDR052C 885 - CCTATTTTCAATATTGGGTA G|302|R G|302|S DBF4 DumbBell Former 704.0 0 0 0 0 -2.1791171161829634 P32325 0.0 0.0 42.346710754729706 30.0 0.0 yes 1936 chrIV_559776 5935 essential YDR052C 830 - TCCATTCCAAAGTTATTATG W|283|S W|283|* W|283|C W|283|* DBF4 DumbBell Former 704.0 0 0 0 0 -1.0347021142865196 P32325 0.0 0.0 40.81624286177987 30.0 0.0 no 1937 chrIV_559854 5937 essential YDR052C 752 - TATCGTCTCTTTTAGTTCTG D|257|H D|257|N D|256|H D|256|N DBF4 DumbBell Former 704.0 0 0 0 0 -0.6181180439497288 P32325 0.00567963905632496 0.01693686656653881 0.0 0.0 44.92011442617314 35.0 0.0 no 1938 chrIV_560179 5939 essential YDR052C 427 - ATCTCTGCGTTTGTCCATCT D|149|H D|149|N R|148|T R|148|K DBF4 DumbBell Former 704.0 0 0 0 0 -1.1320177966578888 P32325 0.05473775416612625 0.2531746029853821 0.07590746879577638 0.9602435827255248 0.4196609854698181 -0.17930300533771515 1.6556129455566406 -0.3942620158195496 54.81502835455348 45.0 0.0 no 1939 chrIV_560340r 5943 essential YDR052C 263 + TGTCCAAGTCAGCAAAGGTA silent|GTC>GTG|V|89 silent|GTC>GTT|V|89 Q|90|E Q|90|* DBF4 DumbBell Former 704.0 0 0 0 1 -0.0723356790085639 P32325 0.5659663677215576 47.711177664818194 45.0 0.0 no 1940 chrIV_560374 5946 essential YDR052C 232 - AGACCTGGCCCTTTCTATTC R|83|S silent|AGG>AGA|R|83 R|83|T R|83|K DBF4 DumbBell Former 704.0 0 1 0 0 0.4369431616788607 P32325 0.0 0.0 0.0 56.42890280092519 50.0 0.0 no 1941 chrIV_561956 5958 essential YDR054C 352 - CACACTTTCCACGGTCTGCA V|124|L V|124|M S|123|T S|123|N CDC34 Cell Division Cycle 295.0 0 0 0 0 -0.363179503606257 P14682 0.9539830088615416 0.9587630033493042 0.9512869715690612 0.9536849856376648 0.01892455480992794 0.0034903869964182377 0.44452935457229614 0.012627097778022291 55.454518509737966 55.00000000000001 0.0 no 1942 chrIV_562018r 5964 essential YDR054C 287 + TTCTATTTTACATCAAAGTG S|97|C S|97|F CDC34 Cell Division Cycle 295.0 0 1 0 0 0.12188972836611185 P14682 0.945252001285553 0.9294660091400146 0.0 0.0 35.44243924831028 25.0 0.0 no 1943 chrIV_562019r 5965 essential YDR054C 286 + TTTCTATTTTACATCAAAGT S|97|C S|97|F CDC34 Cell Division Cycle 295.0 0 1 0 0 0.012805581972993677 P14682 0.945252001285553 0.9294660091400146 0.0 0.0 35.63523087188332 20.0 0.0 no 1944 chrIV_562050 5966 essential YDR054C 258 - CTGCCATCCCTGTAAACGTT G|92|A G|92|D G|92|R G|92|S CDC34 Cell Division Cycle 295.0 0 1 0 0 -0.7065987605635347 P14682 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.0 0.0 0.0 0.0 53.02905072547054 50.0 0.0 no 1945 chrIV_562084r 5971 essential YDR054C 221 + ACCACAGTTTCGATTTACGC P|75|R P|75|L P|75|A P|75|S CDC34 Cell Division Cycle 295.0 0 0 0 0 0.3368495801955568 P14682 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 48.26898300560993 45.0 0.0 no 1946 chrIV_562186r 5973 essential YDR054C 119 + CACTTGGAACATAGGTGTTA T|41|S T|41|I CDC34 Cell Division Cycle 295.0 0 0 0 0 -1.1924635290020955 P14682 0.9491789937019348 0.9472420215606691 0.7184030413627625 0.1798335313796997 43.540339811669696 40.0 0.0 no 1947 chrIV_562227 5977 essential YDR054C 81 - TCTAGTTCTATATGAAATGA E|34|Q E|34|K CDC34 Cell Division Cycle 295.0 0 0 0 0 0.3733122844689405 P14682 0.956179976463318 0.9475290179252625 0.4135667085647583 0.482001543045044 35.230361189329706 25.0 0.0 no 1948 chrIV_570747r 5981 essential YDR060W 101 - CCTTCACGTCCTTGCCTTTG K|40|N silent|AAG>AAA|K|40 silent|GTG>GTC|V|39 silent|GTG>GTA|V|39 MAK21 MAintenance of Killer 1025.0 0 0 0 0 0.5397612339155606 Q12176 0.0549166314303875 58.06701131522567 55.00000000000001 1.0 no 1949 chrIV_570905r 5984 essential YDR060W 259 - GTCAGCATCCTCGTCAGCGA D|93|H D|93|N A|92|P A|92|T MAK21 MAintenance of Killer 1025.0 0 0 0 0 -1.6585532360027233 Q12176 0.15187080204486847 0.5040322542190552 0.17437100410461426 0.35104462504386896 59.304423232101094 60.0 1.0 no 1950 chrIV_570981r 5987 essential YDR060W 335 - CTACATCTTCGAGTTTGTGT V|118|L V|118|I D|117|H D|117|N MAK21 MAintenance of Killer 1025.0 0 0 0 0 0.7245446739604965 Q12176 0.308864563703537 0.5649080872535706 0.14386554062366486 0.4974578320980072 47.031506265843284 40.0 1.0 no 1951 chrIV_571054r 5988 essential YDR060W 408 - GCATGTTCCTTCTCTTGAGC A|143|P A|143|T MAK21 MAintenance of Killer 1025.0 0 0 0 0 0.3238035467566862 Q12176 0.17543944716453552 0.3112259805202484 55.64634215355579 50.0 1.0 no 1952 chrIV_571055r 5989 essential YDR060W 409 - TGCATGTTCCTTCTCTTGAG A|143|P A|143|T MAK21 MAintenance of Killer 1025.0 0 0 0 0 -0.3352122645938992 Q12176 0.17543944716453552 0.3112259805202484 51.49736350394653 45.0 1.0 no 1953 chrIV_571192r 5991 essential YDR060W 546 - TTCTCTGCAGATTCTGATTC E|188|D silent|GAG>GAA|E|188 E|188|Q E|188|K MAK21 MAintenance of Killer 1025.0 0 0 0 0 -0.6153913662716364 Q12176 0.6054878234863281 0.5151856541633606 0.812082827091217 47.054469448602674 40.0 1.0 no 1954 chrIV_571300r 5993 essential YDR060W 654 - TCCAATGGAATTTCATACCA L|224|F silent|TTG>TTA|L|224 D|225|H D|225|N MAK21 MAintenance of Killer 1025.0 0 0 0 0 0.793779175276447 Q12176 0.1141042709350586 0.06238872185349464 0.15991514921188354 43.83049202231409 35.0 1.0 no 1955 chrIV_571324r 5995 essential YDR060W 678 - TCATCATTTTGTCCAACTTG D|233|H D|233|N D|232|H D|232|N MAK21 MAintenance of Killer 1025.0 0 0 0 0 -0.0339464873120901 Q12176 0.0871630534529686 0.3025898039340973 0.0829717144370079 0.4299396574497223 44.247037759815036 35.0 1.0 no 1956 chrIV_571425 5996 essential YDR060W 776 + TTACTATGAGGAGTTTACAA Y|260|* silent|TAC>TAT|Y|260 MAK21 MAintenance of Killer 1025.0 0 0 0 0 -1.5794234918232073 Q12176 38.18108763573082 30.0 1.0 no 1957 chrIV_571797r 6002 essential YDR060W 1151 - TAACGTGAATAATTGGATCG V|390|L V|390|I MAK21 MAintenance of Killer 1025.0 0 0 0 0 0.3940421643440295 Q12176 0.21429000794887546 0.42801377177238464 36.097045220784025 35.0 1.0 no 1958 chrIV_571941 6004 essential YDR060W 1292 + GTCATATTTACTACTGAAGT S|432|* S|432|L MAK21 MAintenance of Killer 1025.0 0 0 0 0 -1.25967065994301 Q12176 0.0 39.45029186719614 30.0 1.0 no 1959 chrIV_572642 6008 essential YDR060W 1993 + TTCTTCAAGTTTGTTCTCAT L|666|V L|666|F Q|667|E Q|667|* MAK21 MAintenance of Killer 1025.0 0 0 0 0 0.5983752937629883 Q12176 1.0 0.09457972645759584 0.0 44.2759667645131 30.0 1.0 no 1960 chrIV_572691 6009 essential YDR060W 2042 + TTTCTTCTTATTAATCCAGT F|682|L silent|TTC>TTT|F|682 F|683|L silent|TTC>TTT|F|683 MAK21 MAintenance of Killer 1025.0 0 0 0 0 1.0645892825735566 Q12176 1.0 0.03764601796865463 42.08919515365028 25.0 1.0 no 1961 chrIV_572936r 6011 essential YDR060W 2290 - CTCTGTTTCTCCTGTCACAT E|770|Q E|770|K MAK21 MAintenance of Killer 1025.0 0 0 0 0 -0.5147729036308099 Q12176 0.5867488384246826 0.8470582365989685 53.711739355909174 45.0 1.0 no 1962 chrIV_576585 6016 essential YDR062W 111 + TATCAAGTCAAGTCACGTCA Q|39|E Q|39|* LCB2 Long-Chain Base 561.0 0 1 0 0 1.629497391958494 P40970 1.0 44.172227414400986 40.0 1.0 no 1963 chrIV_576834 6022 essential YDR062W 360 + TGCTTTTCTAGACCAACTAC C|121|W silent|TGC>TGT|C|121 LCB2 Long-Chain Base 561.0 0 0 0 0 0.370898319663681 P40970 0.009301037527620792 45.24515111469674 40.0 1.0 no 1964 chrIV_577181r 6029 essential YDR062W 710 - TAACTAAACACTTTTTATCG V|243|L V|243|I LCB2 Long-Chain Base 561.0 0 0 0 0 0.8517909644751219 P40970 0.07647588104009627 1.0 33.49475467304825 25.0 1.0 no 1965 chrIV_577225r 6031 essential YDR062W 754 - CCTAACACCTGTTCTAATAG R|258|T R|258|K V|257|L V|257|I LCB2 Long-Chain Base 561.0 0 0 0 0 -0.17210147027900596 P40970 0.0 0.0 0.2993679642677307 0.1894683837890625 43.72587110672117 40.0 1.0 no 1966 chrIV_577272 6035 essential YDR062W 798 + TTCAAGCATGGTGATATGGT F|267|L silent|TTC>TTT|F|267 H|269|D H|269|Y LCB2 Long-Chain Base 561.0 0 0 0 0 -1.900611688117768 P40970 0.007427184376865625 0.0 0.0 45.793286047424715 40.0 1.0 no 1967 chrIV_577373 6037 essential YDR062W 899 + CGCAGAAGGGTTGTTTTCCA A|301|G A|301|V LCB2 Long-Chain Base 561.0 0 0 0 0 0.3764150515664288 P40970 0.0004147975996602327 1.0 52.21899310710478 50.0 1.0 no 1968 chrIV_577461 6038 essential YDR062W 987 + ATCGATGAAGCCCATTCTAT I|330|M silent|ATC>ATT|I|330 LCB2 Long-Chain Base 561.0 0 0 0 0 0.5550848434284089 P40970 0.011386608704924585 47.38392516167129 40.0 1.0 no 1969 chrIV_577642r 6043 essential YDR062W 1171 - TGACTCACTATAACTCACAG E|396|D silent|GAG>GAA|E|396 E|396|Q E|396|K LCB2 Long-Chain Base 561.0 0 0 0 0 -0.15599500865579569 P40970 0.18839402496814728 0.1682726889848709 0.2569824159145355 40.99151151668735 40.0 1.0 no 1970 chrIV_577728r 6045 essential YDR062W 1257 - AATCTTTCAGTACCTTGTCC R|425|T R|425|K LCB2 Long-Chain Base 561.0 0 0 0 0 0.4658133201300804 P40970 0.02009149827063084 0.1495295912027359 49.320419599879415 40.0 1.0 no 1971 chrIV_577416r 6046 essential YDR062W 945 - TTCTTCAATTCAACCAATTT K|321|N silent|AAG>AAA|K|321 L|320|F silent|TTG>TTA|L|320 LCB2 Long-Chain Base 561.0 0 0 0 0 0.7541174800257985 P40970 0.003921026363968849 0.0071104615926742545 39.182219001648214 25.0 1.0 no 1972 chrIV_580135r 6049 essential YDR064W 141 - AACAAGACACCAATTTGAGA L|53|F silent|TTG>TTA|L|53 RPS13 Ribosomal Protein of the Small subunit 151.0 0 0 0 0 0.2082810864806318 P05756 0.05060509964823723 0.4191800057888031 0.08959999680519104 38.58022621633256 35.0 1.0 no 1973 chrIV_580988 6059 high_effect YDR065W 301 + TCAACTCTTTGACTTCATTA silent|CTC>CTG|L|101 silent|CTC>CTT|L|101 N|102|K silent|AAC>AAT|N|102 0 0 0 0 0.17904545740187133 Q12167 1.0 41.21401754393503 30.0 1.0 no 1974 chrIV_581140r 6062 high_effect YDR065W 456 - GCATGTTCGTTCAATGCTAA A|159|P A|159|T 0 0 0 0 -0.026996071046206216 Q12167 0.20040327310562134 0.3812113404273987 46.10780193916099 40.0 1.0 no 1975 chrIV_581218 6063 high_effect YDR065W 531 + GGGCTGTCATATACAAAAGA L|179|V silent|CTG>TTG|L|179 0 0 0 0 -0.3449762819819826 Q12167 0.38936907052993774 41.74324921558792 40.0 1.0 no 1976 chrIV_581399r 6068 high_effect YDR065W 715 - CTCTAGATATTCCTCCCAAA E|245|Q E|245|K 0 0 0 0 0.08703140313723484 Q12167 0.0 0.0 47.73419751179182 40.0 1.0 no 1977 chrIV_581500r 6070 high_effect YDR065W 816 - ACTTTCTGATATTGACTCGA V|279|L V|279|I Q|277|H silent|CAG>CAA|Q|277 0 0 0 0 -0.07800126340384461 Q12167 0.3013918101787567 0.4530268311500549 0.12239695340394975 42.60538416393325 35.0 1.0 no 1978 chrIV_585703 6071 high_effect YDR069C 1997 - CTTCATGAAGACCATCTAGA E|672|Q E|672|K 0 0 0 0 -0.6708828961656562 P32571 0.956179976463318 0.9475290179252625 0.0 0.0 43.6709936477859 40.0 0.0 no 1979 chrIV_586375r 6084 high_effect YDR069C 1322 + ACATTCGCCTGACCCAGTTA H|442|D H|442|Y S|443|W S|443|L 0 1 0 0 0.7504341984414127 P32571 0.9473130106925964 0.9489949941635132 0.9288619756698608 0.9298099875450134 0.23444049060344696 1.0 0.018235435709357258 0.28961899876594543 55.27292832775999 50.0 0.0 no 1980 chrIV_586932 6090 high_effect YDR069C 768 - AACATTTTAATCTCACTATT M|262|I M|262|I 0 0 0 0 0.05402024664459463 P32571 0.9553959965705872 0.9553959965705872 0.031793262809515 0.031793262809515 35.31847233629446 20.0 0.0 no 1981 chrIV_587084 6094 high_effect YDR069C 616 - TATCAGTAGTATCTCCATTT silent|CTG>CTC|L|211 silent|CTG>CTA|L|211 0 0 0 0 0.5902908849594601 P32571 44.47860371502736 30.0 0.0 no 1982 chrIV_587675 6100 high_effect YDR069C 25 - ACGAATACACTCATCCCTTA R|15|P R|15|H 0 0 0 0 -0.14803577233000606 P32571 0.9099509716033936 0.9570810198783876 0.27272942662239075 0.15877912938594818 46.4272862513696 40.0 0.0 no 1983 chrIV_607999r 6101 essential YDR081C 2060 + ACTTCCTTCAAGCACGGCCA L|688|V L|688|F P|689|A P|689|S PDC2 Pyruvate DeCarboxylase 925.0 0 0 0 0 0.17147930038459344 P32896 0.9512209892272948 0.9587849974632264 0.9562489986419678 0.9498909711837769 56.79443252071303 55.00000000000001 0.0 no 1984 chrIV_608184 6103 essential YDR081C 1878 - GTACTGACATTATAATCTAA S|632|T S|632|N PDC2 Pyruvate DeCarboxylase 925.0 0 0 0 0 0.7534987330201852 P32896 0.9512869715690612 0.9536849856376648 0.057308424264192574 0.11687537282705307 34.86900825952614 25.0 0.0 no 1985 chrIV_608575 6110 essential YDR081C 1487 - ATACATCAAAATTATCATCA V|502|L V|502|I D|501|H D|501|N PDC2 Pyruvate DeCarboxylase 925.0 0 0 0 0 0.7411504474862711 P32896 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 0.4250427484512329 0.22890524566173556 0.1092500388622284 0.5422669649124146 33.01183494194265 20.0 0.0 no 1986 chrIV_608820 6113 essential YDR081C 1242 - TCATTCAAATGTATCATTTC E|421|Q E|421|K L|419|F silent|TTG>TTA|L|419 PDC2 Pyruvate DeCarboxylase 925.0 0 0 0 0 0.3035590776085251 P32896 0.956179976463318 0.9475290179252625 0.9587849974632264 0.4785538911819458 0.8205386996269226 0.6885594725608826 36.58695225928284 25.0 0.0 no 1987 chrIV_609343r 6124 essential YDR081C 716 + TCCTGTGTCACAATCAATGT P|240|R P|240|L P|240|A P|240|S PDC2 Pyruvate DeCarboxylase 925.0 0 0 0 0 0.16029002641499773 P32896 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.5976054668426514 0.3360927104949951 0.7889354228973389 0.8154333233833313 46.76693117303222 40.0 0.0 no 1988 chrIV_609411 6127 essential YDR081C 651 - TCATATTTGCCCACGACAAC D|224|H D|224|N PDC2 Pyruvate DeCarboxylase 925.0 0 0 0 0 0.2847467067409182 P32896 0.9486550092697144 0.956179976463318 0.016253553330898285 0.4452823698520661 47.45521785610345 45.0 0.0 no 1989 chrIV_609513 6130 essential YDR081C 549 - TCATATTGAGCATAATCCAA E|190|Q E|190|K PDC2 Pyruvate DeCarboxylase 925.0 0 0 0 0 0.35531551338830925 P32896 0.956179976463318 0.9475290179252625 0.07367861270904541 0.0618499219417572 40.1527634300013 30.0 0.0 no 1990 chrIV_609529r 6131 essential YDR081C 530 + TCTCTCCTACAACCTACCGT silent|CTC>CTG|L|178 silent|CTC>CTT|L|178 L|178|V L|178|F PDC2 Pyruvate DeCarboxylase 925.0 0 0 0 0 -0.4853383867205371 P32896 0.9512209892272948 0.9587849974632264 0.0 0.0 54.4202077615501 50.0 0.0 no 1991 chrIV_609577r 6132 essential YDR081C 482 + TTTCTCCAAAATTCCTCCAA F|162|L silent|TTC>TTT|F|162 S|163|C S|163|F PDC2 Pyruvate DeCarboxylase 925.0 0 0 0 0 -0.4608328703448887 P32896 0.9387490153312684 0.945252001285553 0.9294660091400146 1.0 0.05098119750618935 0.04798310995101929 45.56659581998309 35.0 0.0 no 1992 chrIV_609621 6133 essential YDR081C 441 - TCTTCAAATGTCCAGACTTT E|154|Q E|154|K E|153|Q E|153|K PDC2 Pyruvate DeCarboxylase 925.0 0 0 0 0 0.08829894483696997 P32896 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.016379602253437042 0.012728620320558548 0.034580331295728683 0.026923317462205887 44.25047563493598 35.0 0.0 no 1993 chrIV_609622 6134 essential YDR081C 440 - CTTCAAATGTCCAGACTTTT E|153|Q E|153|K PDC2 Pyruvate DeCarboxylase 925.0 0 0 0 0 0.23996632946584315 P32896 0.956179976463318 0.9475290179252625 0.034580331295728683 0.026923317462205887 43.5333572469018 35.0 0.0 no 1994 chrIV_609629 6136 essential YDR081C 433 - TGTCCAGACTTTTGGGGTTT W|150|C W|150|* W|150|S W|150|* PDC2 Pyruvate DeCarboxylase 925.0 0 0 0 0 0.2256991834760761 P32896 0.8858469724655151 0.8858469724655151 0.0 0.0 52.933775801850565 45.0 0.0 no 1995 chrIV_609732 6137 essential YDR081C 330 - TTTCCCTCGCGATGCTCCGC G|116|A G|116|E G|116|R G|116|R PDC2 Pyruvate DeCarboxylase 925.0 0 0 0 0 -1.146828662050252 P32896 0.9499930143356324 0.9438679814338684 0.941340982913971 0.941340982913971 0.021048028022050858 0.01406032592058182 0.010069576092064379 0.010069576092064379 62.16785953592967 65.0 0.0 no 1996 chrIV_609836r 6140 essential YDR081C 223 + TTCGGAAAATTTTACAAGAA R|76|G R|76|W PDC2 Pyruvate DeCarboxylase 925.0 0 0 0 0 0.8692889017546231 P32896 0.8994590044021606 0.9448130130767822 0.006161186844110489 0.0012734585907310247 32.566764966057804 25.0 0.0 no 1997 chrIV_609957r 6143 essential YDR081C 102 + CTGCCAAAAATTCCATCCCA P|36|A P|36|S P|36|R P|36|L PDC2 Pyruvate DeCarboxylase 925.0 0 0 0 0 0.3268126499380452 P32896 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.4938974678516388 0.6607986092567444 0.3093820214271545 0.3544468283653259 49.428062290445844 45.0 0.0 no 1998 chrIV_610740 6150 essential YDR082W 299 + TACTTCAGACTCTTCATTGG T|101|S T|101|I S|102|* S|102|L 0 0 0 0 0.4723320466321521 P38960 0.801864743232727 0.02059582993388176 0.132466122508049 45.07637929477596 40.0 1.0 no 1999 chrIV_610741 6151 essential YDR082W 300 + ACTTCAGACTCTTCATTGGT T|101|S T|101|I S|102|* S|102|L 0 0 0 0 -0.9442607491366805 P38960 0.801864743232727 0.02059582993388176 0.132466122508049 48.444030259373896 40.0 1.0 no 2000 chrIV_610850 6153 essential YDR082W 409 + GCTTAACTCTTCATGTCTAC silent|GGC>GGG|G|137 silent|GGC>GGT|G|137 T|139|S T|139|I 0 0 0 0 0.2416881446688963 P38960 0.4276593327522278 0.1606457233428955 45.80690467312058 40.0 1.0 no 2001 chrIV_611368r 6160 essential YDR082W 930 - GACTTTGCTGATGTCCTATT K|316|N silent|AAG>AAA|K|316 0 0 0 0 -0.2963374376198885 P38960 0.0307795237749815 0.7701200246810913 48.925909650391255 40.0 1.0 no 2002 chrIV_611369r 6162 essential YDR082W 931 - TGACTTTGCTGATGTCCTAT K|316|N silent|AAG>AAA|K|316 0 0 0 0 0.1844536322297141 P38960 0.0307795237749815 0.7701200246810913 48.6160752525371 40.0 1.0 no 2003 chrIV_617772r 6163 essential YDR087C 512 + TCATATCGTCGATATTCTGC H|172|D H|172|Y I|173|M silent|ATC>ATT|I|173 RRP1 Ribosomal RNA Processing 278.0 0 0 0 0 0.5139668303475052 P35178 0.0 0.0 0.04276888072490692 45.281692593829355 40.0 0.0 no 2004 chrIV_618088 6170 essential YDR087C 199 - ATGCAATTCACCTAATTCAT L|72|F silent|TTG>TTA|L|72 RRP1 Ribosomal RNA Processing 278.0 0 0 0 0 0.462254488848947 P35178 0.0 41.90016987796719 30.0 0.0 no 2005 chrIV_618098r 6171 essential YDR087C 186 + CAACGTTTAGCCAATGAATT R|64|G R|64|C RRP1 Ribosomal RNA Processing 278.0 0 0 0 0 0.2604923588272373 P35178 0.07030832022428513 0.007893314585089684 40.858774344057736 35.0 0.0 no 2006 chrIV_618196 6173 essential YDR087C 91 - GTTCTCCTTGAACTGTTTAG E|36|D silent|GAG>GAA|E|36 E|36|Q E|36|K RRP1 Ribosomal RNA Processing 278.0 0 0 0 0 -0.3433921516947959 P35178 0.5350052714347839 0.5541599988937378 0.9974730014801024 46.32034936248437 40.0 0.0 no 2007 chrIV_619015 6178 essential YDR088C 611 - CCCATAGTGTTTCATCAGTT W|210|S W|210|* W|210|C W|210|* SLU7 Synergistic Lethal with U5 snRNA 382.0 0 1 0 0 0.09396772337463573 Q02775 0.9205849766731262 0.9208570122718812 0.22513628005981445 0.10617734491825104 51.148438720450834 40.0 0.0 no 2008 chrIV_618960r 6179 essential YDR088C 663 + GAACTTTACAAGGATTCCGT L|223|V L|223|F SLU7 Synergistic Lethal with U5 snRNA 382.0 0 0 0 0 0.23449234458117865 Q02775 0.9703750014305116 0.9798439741134644 0.0 0.0 43.924963346140544 40.0 0.0 no 2009 chrIV_619016 6181 essential YDR088C 610 - CCATAGTGTTTCATCAGTTT W|210|S W|210|* SLU7 Synergistic Lethal with U5 snRNA 382.0 0 1 0 0 -0.4429756124958624 Q02775 0.9205849766731262 0.22513628005981445 47.37886561974455 35.0 0.0 no 2010 chrIV_619118 6183 essential YDR088C 508 - ACCGTACCATCTATCTTTTC G|176|R G|176|S G|176|A G|176|D SLU7 Synergistic Lethal with U5 snRNA 382.0 0 1 0 0 0.0782246206117789 Q02775 0.9727219939231871 0.9916149973869324 0.9903749823570251 0.9780880212783812 0.0 0.0 0.0 0.0 49.18405373912475 40.0 0.0 no 2011 chrIV_619145r 6185 essential YDR088C 478 + TACGAGCTACTGATGATGAC R|161|G R|161|* A|162|G A|162|V SLU7 Synergistic Lethal with U5 snRNA 382.0 0 0 0 0 -0.1840719765244482 Q02775 0.9288319945335388 0.9672009944915771 0.9664270281791688 0.3527111411094665 0.319890171289444 0.2994993329048157 42.89939548506953 45.0 0.0 no 2012 chrIV_619301 6193 essential YDR088C 325 - ATCTCGGACGGACATCTTCT D|115|H D|115|N R|114|P R|114|Q SLU7 Synergistic Lethal with U5 snRNA 382.0 0 0 0 0 0.2067397548273222 Q02775 0.965224027633667 0.97645902633667 0.9368820190429688 0.9689509868621826 0.17627455294132233 0.6663485169410706 0.2337057590484619 0.5092846751213074 50.697406039617825 50.0 0.0 no 2013 chrIV_619353r 6195 essential YDR088C 270 + TCAGAACCAAAAATTGGTAT S|91|* S|91|L P|93|A P|93|S SLU7 Synergistic Lethal with U5 snRNA 382.0 0 0 0 0 -0.3846001817662844 Q02775 0.9594640135765076 0.9763929843902588 0.9679129719734192 0.21338315308094025 0.5553873777389526 0.07966885715723038 36.299469705450925 30.0 0.0 no 2014 chrIV_619484 6199 essential YDR088C 142 - CTTCCCTTCTTGTTCTTTGG silent|GGG>GGC|G|53 silent|GGG>GGA|G|53 G|53|A G|53|E SLU7 Synergistic Lethal with U5 snRNA 382.0 0 0 0 0 -0.18013833177675068 Q02775 0.9732409715652466 0.9595270156860352 0.5858718156814575 0.9737457633018494 54.18794417031921 45.0 0.0 no 2015 chrIV_627282 6204 essential YDR091C 1233 - TTCATAGAAACATTCAATTT M|417|I M|417|I RLI1 RNase L Inhibitor 608.0 0 0 0 0 0.6158899621931861 Q03195 0.17079803347587585 0.17079803347587585 0.8827999830245972 0.8827999830245972 33.21660433371193 20.0 0.0 no 2016 chrIV_627336r 6205 essential YDR091C 1176 + ACTTTGATCAAATTACTAGC T|393|S T|393|I RLI1 RNase L Inhibitor 608.0 0 1 0 0 0.5626346304099954 Q03195 0.020388208329677585 0.009685697965323923 37.63684465617485 30.0 0.0 no 2017 chrIV_627381r 6206 essential YDR091C 1131 + TCCGAAATCCTTGTTATGAT silent|TCC>TCG|S|378 silent|TCC>TCT|S|378 S|378|C S|378|F RLI1 RNase L Inhibitor 608.0 0 0 0 1 0.5289840714695191 Q03195 0.06058798730373384 0.026173053309321404 43.82633378005364 35.0 0.0 no 2018 chrIV_627535 6208 essential YDR091C 980 - AAGCTTCAGTTCTGAATCTC A|333|P A|333|T E|332|Q E|332|K RLI1 RNase L Inhibitor 608.0 0 0 0 0 -0.1899052533205744 Q03195 0.4458625912666321 0.4222314953804016 0.2497299462556839 0.5416806936264038 0.34439998865127563 0.1858000010251999 44.932413557030536 40.0 0.0 no 2019 chrIV_627837r 6210 essential YDR091C 675 + GAACTGCAAAGATTTGCCAT L|227|V silent|CTG>TTG|L|227 Q|228|E Q|228|* RLI1 RNase L Inhibitor 608.0 0 0 0 0 0.5862482645302112 Q03195 0.009938114322721958 0.0 0.22380000352859494 43.7422762289612 40.0 0.0 no 2020 chrIV_627901r 6211 essential YDR091C 611 + CTACATCAAAATTTTACAGT Y|205|* silent|TAC>TAT|Y|205 I|206|M silent|ATC>ATT|I|206 RLI1 RNase L Inhibitor 608.0 0 0 0 0 0.7667403882503411 Q03195 0.11211393773555756 -1.6649999618530271 34.904146877952144 25.0 0.0 no 2021 chrIV_627990r 6213 essential YDR091C 522 + AACATTCCTCGTGCTATTAA N|175|K silent|AAC>AAT|N|175 P|177|A P|177|S RLI1 RNase L Inhibitor 608.0 0 0 0 0 -0.2007586190241593 Q03195 0.9549760222434998 0.148651123046875 0.02663949690759182 44.214735113419685 35.0 0.0 no 2022 chrIV_628128 6214 essential YDR091C 387 - TCATCAAAACGACCTAAATT D|136|H D|136|N D|135|H D|135|N RLI1 RNase L Inhibitor 608.0 0 0 0 0 0.4597827452278648 Q03195 0.0849156305193901 0.9099048972129822 0.02456358820199966 0.09316888451576233 0.10520000010728836 0.17520000040531158 36.213515838864396 30.0 0.0 no 2023 chrIV_681231r 6227 essential YDR113C 364 + TACGCAAAAACGACCAACTC R|123|G R|123|C silent|CGC>CGG|R|123 silent|CGC>CGT|R|123 0 1 0 0 -0.6804321151092559 P40316 0.8776019811630249 0.8776469826698303 0.4515725672245026 0.12245598435401915 40.31699954166146 45.0 0.0 no 2024 chrIV_681363 6230 essential YDR113C 235 - TCTTCCTTGTTGTTGCGCAT R|85|T R|85|K G|84|A G|84|E 0 0 0 0 -0.8551500583722028 P40316 0.9511560201644896 0.970902979373932 0.9101750254631042 0.8975480198860168 0.0 0.0 0.4740979373455048 0.2595868408679962 54.95278802844928 45.0 0.0 no 2025 chrIV_681589 6234 essential YDR113C 9 - TTCTCTTTATCTTCGTTAGC E|9|D silent|GAG>GAA|E|9 E|9|Q E|9|K 0 0 0 0 0.12444458804930375 P40316 0.9236429929733276 0.9315000176429749 0.9194509983062744 0.0 0.0 0.0 46.45673579294345 35.0 0.0 no 2026 chrIV_685891r 6235 essential YDR118W 12 - TCAATGAAATAATCATTAAT D|11|H D|11|N 0 0 0 0 -0.04641310166985796 Q04601 0.14821258187294006 0.5353705883026123 28.302436630103674 15.0 1.0 no 2027 chrIV_685959 6238 essential YDR118W 77 + CCTTGCTATTTACAGAGTCT L|27|V L|27|F A|28|G A|28|V 0 0 0 0 1.4174478614874375 Q04601 0.07205794751644135 0.2636072039604187 0.18390224874019626 0.4604506194591522 48.66921831492749 40.0 1.0 no 2028 chrIV_686005r 6241 essential YDR118W 126 - ACCAAGTTTATATTTCTTAT L|48|F silent|TTG>TTA|L|48 V|49|L V|49|M 0 0 0 0 0.7224003189350352 Q04601 0.2829152345657349 0.1569022685289383 0.01275321189314127 38.207537693816334 20.0 1.0 no 2029 chrIV_686362 6248 essential YDR118W 480 + GTTCACGTAGTATTCAATGA H|162|D H|162|Y H|162|Q silent|CAC>CAT|H|162 0 0 0 0 0.6541852316082111 Q04601 0.0 0.0 0.0 42.14590412312134 35.0 1.0 no 2030 chrIV_686930r 6256 essential YDR118W 1051 - GAGCTTATTCTGTATAGAAA K|356|N silent|AAG>AAA|K|356 0 0 0 0 0.4898536216735765 Q04601 0.5228490829467773 38.213456338904855 30.0 1.0 no 2031 chrIV_687211r 6259 essential YDR118W 1332 - TTCACGTCGATTATTGAGCT silent|GTG>GTC|V|450 silent|GTG>GTA|V|450 V|450|L V|450|M 0 0 0 0 0.3890429194133638 Q04601 0.8203772306442261 0.2252189517021179 46.091352305201156 40.0 1.0 no 2032 chrIV_721124r 6263 no_effect YDR133C 151 + CTACACTGGTGCCGCTGTTA T|52|R T|52|I L|53|V silent|CTG>TTG|L|53 0 0 0 0 -0.1635460892480784 Q03904 0.9476869702339172 0.9472420215606691 0.9512209892272948 55.8072448300008 55.00000000000001 0.0 no 2033 chrIV_721171r 6266 no_effect YDR133C 104 + ACTGAAAAGCCAACCCAACA L|36|V silent|CTG>TTG|L|36 0 0 0 0 -0.4173533531562357 Q03904 0.9512209892272948 45.074941499212684 45.0 0.0 no 2034 chrIV_730978 6269 high_effect YDR138W 400 + CATCTACGTTTTTGAAGTTT S|135|C S|135|F T|136|R T|136|M HPR1 HyPerRecombination 752.0 0 0 0 0 0.5102328516544904 P17629 0.04344741255044937 0.047609709203243256 0.3162444233894348 0.07012523710727693 40.77516407959836 30.0 1.0 no 2035 chrIV_731002r 6270 high_effect YDR138W 427 - TTCGATACGTGATTCAGCAT E|149|Q E|149|K HPR1 HyPerRecombination 752.0 0 0 0 0 -0.3031079656262965 P17629 0.5517855882644653 0.8512928485870361 45.317257131987965 40.0 1.0 no 2036 chrIV_731042 6273 high_effect YDR138W 464 + ATCTGTTGAGCCAGTATCAT S|156|C S|156|F HPR1 HyPerRecombination 752.0 0 0 0 0 -1.7321118735835503 P17629 0.044434890151023865 0.04471350088715553 49.543351996781844 40.0 1.0 no 2037 chrIV_731094r 6276 high_effect YDR138W 519 - TGGCGCAGCTTTTCGTATAA R|179|P R|179|H silent|CTG>CTC|L|178 silent|CTG>CTA|L|178 HPR1 HyPerRecombination 752.0 0 0 0 0 1.2836817922102213 P17629 0.0 0.0 49.71623546066144 45.0 1.0 no 2038 chrIV_731114r 6277 high_effect YDR138W 539 - TAGCTAAAATATCGTTCCAG A|186|P A|186|T HPR1 HyPerRecombination 752.0 0 0 0 0 0.6828620676024265 P17629 0.2473534643650055 0.5135117173194885 39.976704228350506 35.0 1.0 no 2039 chrIV_731164r 6278 high_effect YDR138W 589 - TTTCATATTATAATGTTTGA M|202|I M|202|I HPR1 HyPerRecombination 752.0 0 0 0 0 0.3651502969932917 P17629 0.11106601357460022 0.11106601357460022 33.189390666051786 15.0 1.0 no 2040 chrIV_731672 6285 high_effect YDR138W 1094 + CACTCTTCGACCTACCATTA T|366|S T|366|I L|367|V L|367|F HPR1 HyPerRecombination 752.0 0 0 0 0 -0.19371265125381545 P17629 0.11366355419158936 0.8374221324920654 0.5652036666870117 0.19295601546764374 49.95320502332397 45.0 1.0 no 2041 chrIV_731894r 6289 high_effect YDR138W 1319 - GCTTTTTGTTAACTTCATCA K|446|N silent|AAG>AAA|K|446 HPR1 HyPerRecombination 752.0 0 0 0 0 -0.30965433005841675 P17629 0.1292140930891037 43.50672247738328 30.0 1.0 no 2042 chrIV_732040r 6291 high_effect YDR138W 1465 - TTCTTTAAAGCCATCGATCT E|495|Q E|495|K HPR1 HyPerRecombination 752.0 0 0 0 0 0.9117602109287696 P17629 0.5764325261116028 0.9006116986274719 44.31051910812124 35.0 1.0 no 2043 chrIV_732180r 6292 high_effect YDR138W 1605 - TCAATTTTATCTAGACCAGT E|542|Q E|542|K HPR1 HyPerRecombination 752.0 0 0 0 0 0.8295600306067217 P17629 0.5313805341720581 0.9960793256759644 41.84600179468663 30.0 1.0 no 2044 chrIV_732219r 6293 high_effect YDR138W 1644 - GCTGCTTCATAGACACCTTC A|555|P A|555|T A|554|P A|554|T HPR1 HyPerRecombination 752.0 0 1 0 0 0.18307320883017247 P17629 0.025960236787796017 0.041782259941101074 0.25173354148864746 0.5101001262664795 52.951772531235626 50.0 1.0 no 2045 chrIV_736238r 6297 essential YDR141C 3737 + TGCATTTTTGTTTAACTACG A|1247|G A|1247|V DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 1.06228988528345 Q03921 0.3945559859275818 0.3049089908599853 39.717737647156866 30.0 0.0 no 2046 chrIV_736273r 6298 essential YDR141C 3702 + TCCATGTTAAAAAGATTAAG silent|TCC>TCG|S|1235 silent|TCC>TCT|S|1235 S|1235|C S|1235|F DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 0.4222042534690494 Q03921 0.08334934711456299 0.11438111960887908 32.157966324135536 25.0 0.0 no 2047 chrIV_736390r 6302 essential YDR141C 3585 + ACAATACCACATTTATTGTA T|1196|R T|1196|I P|1198|A P|1198|S DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 0.5620739976799958 Q03921 0.04417715221643448 0.03776078298687935 0.07421551644802094 0.2940079271793365 38.64444449052093 25.0 0.0 no 2048 chrIV_736793r 6308 essential YDR141C 3182 + TTACCTTGTCACCGAGGAAA Y|1062|* silent|TAC>TAT|Y|1062 L|1063|V L|1063|F DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 -0.3711357741918697 Q03921 0.0 0.0 47.27109018686974 45.0 0.0 no 2049 chrIV_736799r 6309 essential YDR141C 3176 + ACATGGTTACCTTGTCACCG H|1060|D H|1060|Y DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 -0.05769385162728935 Q03921 0.02170853689312935 0.2974132299423218 52.12518626170845 50.0 0.0 no 2050 chrIV_736816r 6310 essential YDR141C 3159 + GAGCTATTAGAGATTTCACA L|1055|V silent|CTA>TTA|L|1055 DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 -0.7820282877801712 Q03921 0.029853612184524536 42.100475679032286 35.0 0.0 no 2051 chrIV_736846r 6312 essential YDR141C 3129 + CCAATAGCTTTGCTTCTGGG P|1044|R P|1044|L DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 0.5768331326696927 Q03921 0.03748738393187523 0.038613520562648766 51.69908107545746 50.0 0.0 no 2052 chrIV_736968 6318 essential YDR141C 3010 - CTCAAAATAAACAATGCTTT E|1010|Q E|1010|K DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 -1.3393160942683715 Q03921 0.4990961253643036 0.03465355187654495 32.938099345130865 25.0 0.0 no 2053 chrIV_737002 6319 essential YDR141C 2976 - ACATAGGCCGTTACAATAAG V|999|L V|999|M DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 0.051313136371314017 Q03921 0.05341794341802597 0.010065300390124321 42.230496765323146 40.0 0.0 no 2054 chrIV_737110r 6321 essential YDR141C 2865 + CTCAGACTATCACACGATAA silent|CTC>CTG|L|956 silent|CTC>CTT|L|956 L|958|V silent|CTA>TTA|L|958 DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 1 0.3137232009513221 Q03921 0.10419713705778122 41.311439944628546 40.0 0.0 no 2055 chrIV_737373 6325 essential YDR141C 2605 - AACGTCTTCATTCTTCCATA V|875|L V|875|I D|874|H D|874|N DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 -0.07146419512622082 Q03921 0.2928543984889984 0.7442781925201416 0.0399751253426075 0.3429391384124756 46.181437902356656 35.0 0.0 no 2056 chrIV_737348r 6327 essential YDR141C 2627 + CACATATAAAAGTTTGCTGT T|877|R T|877|I DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 -0.304795530551899 Q03921 0.013513181358575821 0.013509459793567656 37.90317640495118 30.0 0.0 no 2057 chrIV_737788 6331 essential YDR141C 2190 - GCACTTTCAATAAATTTGGA S|736|T S|736|N A|737|P A|737|T DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 0.0984769634228252 Q03921 0.22990430891513824 0.19437743723392487 0.10322768986225128 0.21563708782196045 38.56236252522655 30.0 0.0 no 2058 chrIV_737837 6332 essential YDR141C 2141 - TCTTGACACCTAGTATTTGA K|720|N silent|AAG>AAA|K|720 V|719|L V|719|I DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 0.166085942505157 Q03921 0.14654862880706787 0.0818621888756752 0.5340885519981384 44.56592136833075 35.0 0.0 no 2059 chrIV_737845r 6334 essential YDR141C 2130 + GATCCACGCCATCAAATACT P|712|A P|712|S P|712|R P|712|L DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 0.8886556747812694 Q03921 0.5589197278022766 0.32630404829978943 0.06349510699510574 0.06055422499775887 47.70676407383786 45.0 0.0 no 2060 chrIV_737865 6335 essential YDR141C 2113 - ATCTTTTAAAGATTTCCATA D|711|H D|711|N DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 -0.3242952565407113 Q03921 0.1104152724146843 0.5244233012199402 36.67625137658842 20.0 0.0 no 2061 chrIV_737930r 6336 essential YDR141C 2045 + TAACTACTTATATTCACGCA N|683|K silent|AAC>AAT|N|683 Y|684|* silent|TAC>TAT|Y|684 DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 0.2132862173216656 Q03921 1.0 39.66677760556957 30.0 0.0 no 2062 chrIV_738056r 6340 essential YDR141C 1919 + ACGATCTCACATAAGCTGGT R|641|G R|641|* S|642|C S|642|F DOP1 homolog of A. nidulans DOPey 1698.0 0 1 0 0 -1.9766540851822931 Q03921 0.3672668635845184 0.10263383388519287 0.2631709575653076 47.32475434195567 45.0 0.0 no 2063 chrIV_738253 6341 essential YDR141C 1725 - TCTTTCTCTAAAATGCTAGA E|582|Q E|582|K E|580|D silent|GAG>GAA|E|580 DOP1 homolog of A. nidulans DOPey 1698.0 0 1 0 0 -0.1127629375277776 Q03921 0.4403115212917328 0.719548761844635 0.8403716683387756 39.17370700434947 30.0 0.0 no 2064 chrIV_738297r 6342 essential YDR141C 1678 + AACTTTTGGCCAAAATACGT L|561|V L|561|F DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 0.8162766174379421 Q03921 1.0 0.07809099555015564 41.422757880622726 35.0 0.0 no 2065 chrIV_738447 6346 essential YDR141C 1531 - ATCTTTATCATTAGATGGAA D|517|H D|517|N DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 -1.4236927987989731 Q03921 0.19602160155773166 0.5320866107940674 37.19192422273807 25.0 0.0 no 2066 chrIV_738554r 6348 essential YDR141C 1421 + CATCAAAAACCTAAAAATTT I|475|M silent|ATC>ATT|I|475 DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 0.4322565065938962 Q03921 0.10451976209878923 29.794141826055867 20.0 0.0 no 2067 chrIV_738680r 6350 essential YDR141C 1295 + CATCCCACTTCTCTATTCCT I|433|M silent|ATC>ATT|I|433 P|434|A P|434|S DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 0.3852296149919499 Q03921 0.016688596457242966 0.09142570942640303 0.11455163359642027 55.22611497589828 45.0 0.0 no 2068 chrIV_738759 6352 essential YDR141C 1219 - TATCCTGAATGCAGTTAACA R|412|S silent|AGG>AGA|R|412 R|412|T R|412|K DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 0.00979394840829162 Q03921 0.15166302025318146 0.15772204101085666 1.0 42.53570553465335 35.0 0.0 no 2069 chrIV_738762r 6354 essential YDR141C 1213 + AATCCGTGTTAACTGCATTC S|406|C S|406|F silent|TCC>TCG|S|406 silent|TCC>TCT|S|406 DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 -0.4366208640236787 Q03921 0.043540194630622864 0.04430694505572319 45.4295275131575 40.0 0.0 no 2070 chrIV_738925r 6356 essential YDR141C 1050 + CTTCTCGGTCCTACTGCTGG L|352|V L|352|F silent|CTC>CTG|L|352 silent|CTC>CTT|L|352 DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 -1.8437479728369377 Q03921 0.14955559372901914 0.022436732426285744 57.87994776232847 60.0 0.0 no 2071 chrIV_739124 6363 essential YDR141C 854 - CATCTTCTAAACAACCGACA D|291|H D|291|N E|290|Q E|290|K DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 1.6378693276380107 Q03921 0.15727733075618744 0.15618421137332916 0.4820314049720764 0.8266605734825134 41.83589653406108 40.0 0.0 no 2072 chrIV_739138r 6364 essential YDR141C 837 + CTACTTATCCGATGCCTTGT L|281|V L|281|F DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 0.3648842466425522 Q03921 0.0 0.0 51.65477752307231 45.0 0.0 no 2073 chrIV_739233 6367 essential YDR141C 745 - CCTGTCTAGATGAGAATCGT R|255|T R|255|K D|254|H D|254|N DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 -1.5068432449612066 Q03921 0.5937516689300537 0.9366722106933594 0.05019137635827065 0.5474878549575806 46.617939593507 45.0 0.0 no 2074 chrIV_739233r 6368 essential YDR141C 742 + CCAACGATTCTCATCTAGAC silent|ACC>ACG|T|248 silent|ACC>ACT|T|248 N|249|K silent|AAC>AAT|N|249 DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 1 -0.04697750110950352 Q03921 0.9249188303947448 45.05508349453503 45.0 0.0 no 2075 chrIV_739678r 6379 essential YDR141C 297 + ACGTATATCTTTGAACATAT T|100|R T|100|M DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 -0.2033706442217452 Q03921 0.07514162361621858 0.149067685008049 36.74406551818089 25.0 0.0 no 2076 chrIV_739762 6380 essential YDR141C 216 - AATCTTCGACTTACTTGATA R|78|T R|78|K R|77|P R|77|Q DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 0.2749704008813394 Q03921 0.09363680332899094 0.2494664639234543 0.011197143234312534 0.13486887514591214 39.419712584951526 30.0 0.0 no 2077 chrIV_739871r 6385 essential YDR141C 104 + TGACTCTGTAACAGAATGGG D|36|E silent|GAC>GAT|D|36 S|37|C S|37|F DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 0.12219184850647476 Q03921 0.0 0.03654656931757927 0.05104530230164528 42.269065198902695 45.0 0.0 no 2078 chrIV_739920 6386 essential YDR141C 58 - AGCACGAAACTTCTTCTGTT A|26|P A|26|T R|25|P R|25|H DOP1 homolog of A. nidulans DOPey 1698.0 0 0 0 0 -0.02492122204758984 Q03921 0.3311971724033356 0.7011150121688843 0.2507035434246063 0.3741065561771393 45.25894152958465 40.0 0.0 no 2079 chrIV_746840r 6390 essential YDR145W 105 - GCCATTTCTTGCAACTGTCT M|41|I M|41|I A|42|P A|42|T TAF12 TATA binding protein-Associated Factor 539.0 0 0 0 0 0.017447741284203344 Q03761 0.9553959965705872 0.9553959965705872 0.9573720097541808 0.9523990154266356 0.03934377059340477 0.03934377059340477 0.05915474891662598 0.702425479888916 52.885417566903584 45.0 1.0 no 2080 chrIV_746915r 6391 essential YDR145W 180 - AACATCAATTCCTTGCCCCT M|66|I M|66|I L|65|F silent|TTG>TTA|L|65 TAF12 TATA binding protein-Associated Factor 539.0 0 0 0 0 -1.6014773395082211 Q03761 0.9553959965705872 0.9553959965705872 0.9587849974632264 0.13307806849479675 0.13307806849479675 0.08505111932754518 53.67915578804326 45.0 1.0 no 2081 chrIV_746970r 6393 essential YDR145W 235 - TCTTCTCCTATTCAGTGTAA R|85|T R|85|K R|84|T R|84|K TAF12 TATA binding protein-Associated Factor 539.0 0 0 0 0 -0.1336287191556739 Q03761 0.932735025882721 0.955805003643036 0.932735025882721 0.955805003643036 0.6098545789718628 0.9232492446899414 0.030898839235305783 0.13836312294006348 46.96679063272711 35.0 1.0 no 2082 chrIV_746971r 6394 essential YDR145W 236 - GTCTTCTCCTATTCAGTGTA R|85|T R|85|K R|84|T R|84|K TAF12 TATA binding protein-Associated Factor 539.0 0 0 0 0 -0.3308066640387661 Q03761 0.932735025882721 0.955805003643036 0.932735025882721 0.955805003643036 0.6098545789718628 0.9232492446899414 0.030898839235305783 0.13836312294006348 51.74490260151981 40.0 1.0 no 2083 chrIV_747161r 6396 essential YDR145W 426 - TCATATTCTTGGTTCTCTTC E|149|Q E|149|K TAF12 TATA binding protein-Associated Factor 539.0 0 0 0 0 0.3804580647196273 Q03761 0.956179976463318 0.9475290179252625 0.15349562466144562 0.4887380301952362 46.551760779743745 35.0 1.0 no 2084 chrIV_747205 6398 essential YDR145W 467 + AGTCCGTCATACGAGTATAA silent|GTC>GTG|V|157 silent|GTC>GTT|V|157 R|158|G R|158|C TAF12 TATA binding protein-Associated Factor 539.0 0 0 0 0 0.08379350268748828 Q03761 0.8994590044021606 0.8926740288734436 0.2385920286178589 0.030535208061337468 44.96741542892107 40.0 1.0 no 2085 chrIV_747632r 6408 essential YDR145W 897 - TGCTGCGATTTCAGTGCATC Q|305|H silent|CAG>CAA|Q|305 silent|TCG>TCC|S|304 silent|TCG>TCA|S|304 TAF12 TATA binding protein-Associated Factor 539.0 0 0 0 0 -0.5460176374779133 Q03761 0.9570760130882264 0.082438625395298 52.38098865343551 50.0 1.0 no 2086 chrIV_747674 6409 essential YDR145W 936 + ACTGCCACCAATAATCCCAG T|313|S T|313|I A|314|G A|314|V TAF12 TATA binding protein-Associated Factor 539.0 0 0 0 0 -0.3037879483768468 Q03761 0.9491789937019348 0.9472420215606691 0.9484469890594482 0.9504740238189696 0.7524769902229309 0.2365606725215912 0.3907335698604584 0.30598515272140503 51.61990275501933 50.0 1.0 no 2087 chrIV_747715 6411 essential YDR145W 977 + GACTGAACAATCGAAAGCTA T|327|S T|327|I TAF12 TATA binding protein-Associated Factor 539.0 0 1 0 0 0.05650921460221036 Q03761 0.9491789937019348 0.9472420215606691 0.7196885347366333 0.16608214378356936 38.627759259587656 40.0 1.0 no 2088 chrIV_747915r 6418 essential YDR145W 1180 - TGCTGGTGTATTCAAAGCAC A|400|P A|400|T TAF12 TATA binding protein-Associated Factor 539.0 0 0 0 0 -0.9943296296417392 Q03761 0.9573720097541808 0.9523990154266356 0.11716842651367188 0.14691084623336792 46.598109009898 45.0 1.0 no 2089 chrIV_767194r 6421 no_effect YDR153C 755 + TACTCGCAGGCGTTCTCATA T|253|S T|253|I R|254|G R|254|C ENT5 Epsin N-Terminal homology 411.0 0 0 0 0 0.9395829082618232 Q03769 0.9216309785842896 0.9196789860725404 0.8844469785690308 0.8844919800758362 0.5373481512069702 0.08772365748882294 0.5003599524497986 0.09052461385726927 52.88636078151092 50.0 0.0 no 2090 chrIV_767378 6424 no_effect YDR153C 574 - TCCTTGCTGTCGAATTTTCA G|198|R G|198|R G|198|A G|198|E ENT5 Epsin N-Terminal homology 411.0 0 0 0 0 0.21664960913896464 Q03769 0.9563270211219788 0.9563270211219788 0.9732409715652466 0.9595270156860352 0.015852702781558037 0.015852702781558037 0.13296662271022794 0.02400752529501915 49.09768098481698 40.0 0.0 no 2091 chrIV_767498 6426 no_effect YDR153C 454 - AATCTCCATTTTACCATCAT E|157|D silent|GAG>GAA|E|157 E|157|Q E|157|K ENT5 Epsin N-Terminal homology 411.0 0 0 0 0 0.10371550168022264 Q03769 0.9933249950408936 1.0004899501800537 0.9891330003738404 0.5833665728569031 0.5304238200187683 0.824743926525116 44.75613069554021 30.0 0.0 no 2092 chrIV_767548r 6427 no_effect YDR153C 401 + TCATAAGCATATTTTAACCA H|135|D H|135|Y ENT5 Epsin N-Terminal homology 411.0 0 0 0 0 -0.08754745851079115 Q03769 0.9917020201683044 0.9918540120124816 0.3214758634567261 0.032876066863536835 38.47428429260441 25.0 0.0 no 2093 chrIV_767549r 6428 no_effect YDR153C 400 + CTCATAAGCATATTTTAACC H|135|D H|135|Y ENT5 Epsin N-Terminal homology 411.0 0 0 0 0 0.764374034327663 Q03769 0.9917020201683044 0.9918540120124816 0.3214758634567261 0.032876066863536835 38.906665651613935 30.0 0.0 no 2094 chrIV_767666r 6429 no_effect YDR153C 283 + ACGTTAATTATGGGTCCGAA Y|95|* silent|TAC>TAT|Y|95 ENT5 Epsin N-Terminal homology 411.0 0 0 0 0 0.029036791809628593 Q03769 44.38800763485977 40.0 0.0 no 2095 chrIV_767692 6430 no_effect YDR153C 260 - CCTTTCTTGCCTTTTCGTAT K|93|N silent|AAG>AAA|K|93 R|92|T R|92|K ENT5 Epsin N-Terminal homology 411.0 0 0 0 0 0.4876131613969627 Q03769 0.912319004535675 0.9114800095558168 0.9298490285873412 0.0 0.02745221741497517 0.7743297219276428 52.830291669665705 40.0 0.0 no 2096 chrIV_767806r 6435 no_effect YDR153C 143 + CACACCGAAGCACCTCGCCA T|49|R T|49|I P|50|A P|50|S ENT5 Epsin N-Terminal homology 411.0 0 0 0 0 -1.147842137498039 Q03769 0.8989629745483398 0.9091619849205016 0.9763929843902588 0.9679129719734192 0.0377638041973114 0.1182083934545517 0.6706843376159668 0.9127876758575441 57.822313255303364 65.0 0.0 no 2097 chrIV_767832r 6437 no_effect YDR153C 117 + GCTACAAATACCGATGCTTG A|40|G A|40|V T|41|R T|41|I ENT5 Epsin N-Terminal homology 411.0 0 0 0 0 0.2688939540729791 Q03769 0.9919250011444092 0.991150975227356 0.9026349782943726 0.9128339886665344 0.0 0.0 0.0 0.0 44.73526688506929 45.0 0.0 no 2098 chrIV_767834r 6439 no_effect YDR153C 115 + GTGCTACAAATACCGATGCT A|40|G A|40|V T|41|R T|41|I ENT5 Epsin N-Terminal homology 411.0 0 0 0 0 0.4993144542480287 Q03769 0.9919250011444092 0.991150975227356 0.9026349782943726 0.9128339886665344 0.0 0.0 0.0 0.0 46.83996122101218 45.0 0.0 no 2099 chrIV_767911 6443 no_effect YDR153C 41 - TTGCGGCATTTCTAATATCA A|20|P A|20|T A|19|P A|19|T ENT5 Epsin N-Terminal homology 411.0 0 0 0 0 0.1770989126989198 Q03769 0.9863749742507936 0.9780830144882202 0.921612024307251 0.913320004940033 0.10200691223144533 0.31529057025909424 0.14237990975379944 0.21183335781097407 44.70497349830367 35.0 0.0 no 2100 chrIV_776295r 6446 essential YDR160W 135 - ATGCCAGTGTCTATACTACC G|51|A G|51|D G|51|R G|51|S 0 0 0 0 0.2336367634328431 Q03770 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.6787109375 0.7828340530395508 0.4686373472213745 1.0 51.093670691492825 45.0 1.0 no 2101 chrIV_776492r 6447 essential YDR160W 332 - GAACACGTTTGTTATATGTT V|117|L V|117|I R|116|P R|116|H 0 0 0 0 0.18676745810252326 Q03770 0.9539830088615416 0.9574310183525084 0.9099509716033936 0.9570810198783876 0.27888455986976624 0.4398460388183594 0.25791123509407043 0.14572304487228396 39.84968503622547 30.0 1.0 no 2102 chrIV_776646r 6451 essential YDR160W 486 - ATTCTGGAGTATCTATCGAG R|168|T R|168|K 0 0 0 0 -0.4589790452153091 Q03770 0.932735025882721 0.955805003643036 0.4650857746601105 1.0 43.59652138373781 40.0 1.0 no 2103 chrIV_776712r 6454 essential YDR160W 552 - CTTCTTCTTTTCAGTTTTCT R|190|T R|190|K R|189|T R|189|K 0 0 0 0 0.6550703310502234 Q03770 0.932735025882721 0.955805003643036 0.932735025882721 0.955805003643036 0.4623225927352905 0.7726433277130127 0.5669130682945251 0.97734934091568 46.68469974057388 30.0 1.0 no 2104 chrIV_776944 6458 essential YDR160W 781 + ACATTGAAAAGGTTTTCAAT D|261|E silent|GAC>GAT|D|261 0 0 0 0 1.2060732536385268 Q03770 0.9532920122146606 0.6050557494163513 34.96849503408617 25.0 1.0 no 2105 chrIV_777052 6462 essential YDR160W 889 + TCGGATTATTTTTAACCTCA silent|GTC>GTG|V|297 silent|GTC>GTT|V|297 0 0 0 0 -0.00047472462389491765 Q03770 42.20699335426235 30.0 1.0 no 2106 chrIV_777402 6474 essential YDR160W 1239 + TTACTGGATGTCAGCATAAT L|415|V silent|CTG>TTG|L|415 0 0 0 0 0.18680589800429345 Q03770 0.9512209892272948 0.2276294529438019 42.52078555656095 35.0 1.0 no 2107 chrIV_777561 6478 essential YDR160W 1398 + TCTGTCCGAAATTTGACCTA S|467|C S|467|F silent|GTC>GTG|V|468 silent|GTC>GTT|V|468 0 0 0 0 -0.7888312321842571 Q03770 0.945252001285553 0.9294660091400146 0.0166770052164793 0.09194968640804292 45.9608234212335 40.0 1.0 no 2108 chrIV_777647r 6481 essential YDR160W 1487 - TAGCTAAAAATCGGCCTTTT A|502|P A|502|T 0 0 0 0 -0.05778259808986514 Q03770 0.9573720097541808 0.9523990154266356 0.1199743002653122 0.15127870440483093 42.47683680342777 35.0 1.0 no 2109 chrIV_778002r 6488 essential YDR160W 1842 - TTCTGCAATGCAACAACCCA Q|620|H silent|CAG>CAA|Q|620 L|619|F silent|TTG>TTA|L|619 0 0 0 0 -1.091807217405547 Q03770 0.9570760130882264 0.9587849974632264 0.014306006953120232 0.03918572887778282 48.454462939522784 45.0 1.0 no 2110 chrIV_782595r 6489 essential YDR164C 1598 + ACAATACTTCCCATATTTAA Q|534|E Q|534|* Y|535|* silent|TAC>TAT|Y|535 SEC1 SECretory 724.0 0 0 0 0 0.9331083421932992 P30619 0.9590039849281312 1.0 39.624262281937426 25.0 0.0 no 2111 chrIV_782663r 6490 essential YDR164C 1530 + TCAAGGTTCGTTCCCGCTGT S|511|* S|511|L SEC1 SECretory 724.0 0 0 0 0 -0.5922790270731142 P30619 0.9298099875450134 0.0 57.97797280425471 55.00000000000001 0.0 no 2112 chrIV_782921 6491 essential YDR164C 1275 - CGCAATTTATCTAAGATTGT L|431|F silent|TTG>TTA|L|431 SEC1 SECretory 724.0 0 0 0 0 0.6653761258824891 P30619 0.9587849974632264 0.02421447075903416 38.85027274458025 30.0 0.0 no 2113 chrIV_783006 6493 essential YDR164C 1190 - AATCCATTCCAAATCCGGAT D|403|H D|403|N M|402|I M|402|I SEC1 SECretory 724.0 0 0 0 0 0.0279243766824585 P30619 0.9486550092697144 0.956179976463318 0.9553959965705872 0.9553959965705872 0.034261155873537064 0.17819444835186005 0.4101146459579468 0.4101146459579468 46.589515505893814 40.0 0.0 no 2114 chrIV_783060 6497 essential YDR164C 1136 - TTCTTTCCGCGTTCTCTCCT R|385|T R|385|K E|384|Q E|384|K SEC1 SECretory 724.0 0 0 0 0 -0.16886416092101966 P30619 0.932735025882721 0.955805003643036 0.956179976463318 0.9475290179252625 0.024889852851629257 0.6668177247047424 0.2598307728767395 0.3776290714740753 59.10819001197553 50.0 0.0 no 2115 chrIV_783123 6501 essential YDR164C 1073 - TTTCTTCATCAAAATCTTTC E|364|Q E|364|K E|363|Q E|363|K SEC1 SECretory 724.0 0 0 0 0 0.3924939162968441 P30619 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.031234875321388245 0.024855369701981544 0.0 0.0 36.991444943524534 25.0 0.0 no 2116 chrIV_783232 6502 essential YDR164C 964 - TCTTCCTTGAATATATTCGT R|328|T R|328|K G|327|A G|327|E SEC1 SECretory 724.0 0 0 0 0 1.0186744874202032 P30619 0.932735025882721 0.955805003643036 0.9499930143356324 0.9438679814338684 0.02398508600890636 0.6284221410751343 0.9229223728179932 0.9852852821350098 42.760659756441434 30.0 0.0 no 2117 chrIV_783331 6504 essential YDR164C 865 - TTGCTCACCAGCTTCATTCT E|294|D silent|GAG>GAA|E|294 E|294|Q E|294|K SEC1 SECretory 724.0 0 0 0 0 0.18600128338904906 P30619 0.94931298494339 0.956179976463318 0.9475290179252625 0.2506910562515259 0.050111074000597 0.16537149250507355 54.558662838095806 45.0 0.0 no 2118 chrIV_783701 6511 essential YDR164C 495 - ACAATCTTCCTCACGTTAGT V|172|L V|172|I K|170|N silent|AAG>AAA|K|170 SEC1 SECretory 724.0 0 0 0 0 -1.975916069975619 P30619 0.9539830088615416 0.9574310183525084 0.9355990290641784 0.2642242908477783 0.4773553907871246 0.2360430806875229 48.02511771118884 40.0 0.0 no 2119 chrIV_783840r 6513 essential YDR164C 353 + ACGTTACATTGCTCAAAATT R|119|G R|119|C Y|120|* silent|TAC>TAT|Y|120 SEC1 SECretory 724.0 0 0 0 0 -0.2226560168120496 P30619 0.8994590044021606 0.8926740288734436 0.4306925535202025 0.07555387914180756 39.015678484589785 30.0 0.0 no 2120 chrIV_783756r 6515 essential YDR164C 437 + ACAAATGGAACACTCATTAC Q|147|E Q|147|* SEC1 SECretory 724.0 0 0 0 0 0.6615828470089188 P30619 0.9590039849281312 1.0 37.01464907069118 35.0 0.0 no 2121 chrIV_783899r 6517 essential YDR164C 294 + TGTCACATCAGATTTTTACC H|100|D H|100|Y H|100|Q silent|CAC>CAT|H|100 SEC1 SECretory 724.0 0 0 0 0 0.31678932352410594 P30619 0.9473130106925964 0.9489949941635132 0.9588389992713928 0.09031829982995987 0.13570278882980347 0.10420552641153336 44.12509622656818 35.0 0.0 no 2122 chrIV_783990r 6519 essential YDR164C 203 + CATCGAGGCAATTTACATAT I|69|M silent|ATC>ATT|I|69 SEC1 SECretory 724.0 0 0 0 0 -0.3359320958082105 P30619 0.9598389863967896 0.24822987616062164 41.18651951581796 35.0 0.0 no 2123 chrIV_784060 6520 essential YDR164C 136 - GACATTATTTAAAAGTTCTT V|52|L V|52|I SEC1 SECretory 724.0 0 0 0 0 0.6669390697796506 P30619 0.9539830088615416 0.9574310183525084 0.14046354591846466 0.18989330530166626 33.36137975451425 20.0 0.0 no 2124 chrIV_784113r 6523 essential YDR164C 80 + TCTTATTATCGATAAAACTG L|28|V L|28|F SEC1 SECretory 724.0 0 0 0 0 0.7332826622804935 P30619 0.9512209892272948 0.9587849974632264 0.0 0.0 32.88029601889525 25.0 0.0 no 2125 chrIV_784175r 6525 essential YDR164C 18 + TTACAGAGGAACTATTTGAT Q|8|E Q|8|* SEC1 SECretory 724.0 0 0 0 0 -1.1318469108479021 P30619 0.9590039849281312 0.07024984806776048 37.55723832400685 30.0 0.0 no 2126 chrIV_787432 6534 essential YDR166C 1770 - CAACTCAATCCATTACAATT S|596|T S|596|N L|595|F silent|TTG>TTA|L|595 SEC5 SECretory 971.0 0 0 0 0 -0.8012176039754692 P89102 0.9512869715690612 0.9536849856376648 0.9587849974632264 0.0 0.0 0.0243633221834898 38.8342075144227 30.0 0.0 no 2127 chrIV_787513r 6537 essential YDR166C 1686 + TCATCATTGAAGGATTCTAC S|563|* S|563|L S|564|* S|564|L SEC5 SECretory 971.0 0 0 0 0 0.5911866057623418 P89102 0.9298099875450134 0.9298099875450134 0.3008217513561249 0.7285671234130859 40.246589393540724 35.0 0.0 no 2128 chrIV_787637r 6538 essential YDR166C 1562 + CCAAAAAAGCTTGATCTTGA Q|522|E Q|522|* SEC5 SECretory 971.0 0 0 0 0 0.3530770137348077 P89102 0.9590039849281312 1.0 38.69627367529142 35.0 0.0 no 2129 chrIV_787737r 6539 essential YDR166C 1462 + ACATTGAAAAGTTCCTCGAT H|488|Q silent|CAC>CAT|H|488 SEC5 SECretory 971.0 0 0 0 0 -0.4843605388085029 P89102 0.9588389992713928 0.14222128689289093 41.04393585298885 35.0 0.0 no 2130 chrIV_787738r 6540 essential YDR166C 1461 + CACATTGAAAAGTTCCTCGA H|488|Q silent|CAC>CAT|H|488 SEC5 SECretory 971.0 0 0 0 0 0.1694385065919215 P89102 0.9588389992713928 0.14222128689289093 42.292110246489976 40.0 0.0 no 2131 chrIV_788267 6548 essential YDR166C 935 - ACAAAATTGTTTCTTGGGGT L|318|F silent|TTG>TTA|L|318 SEC5 SECretory 971.0 0 0 0 0 0.2122439340721137 P89102 0.9587849974632264 0.0 42.514001100856376 35.0 0.0 no 2132 chrIV_788482 6552 essential YDR166C 720 - AAACATCTCTTTAAAGATTT C|246|S C|246|Y R|245|T R|245|K SEC5 SECretory 971.0 0 0 0 0 -1.653897865119219 P89102 0.9421560168266296 0.9290120005607604 0.932735025882721 0.955805003643036 0.4211350381374359 1.0 0.5781651139259338 1.0 32.789398921593204 20.0 0.0 no 2133 chrIV_788566 6553 essential YDR166C 636 - TTCTGATAGTTATCCATTAG Q|218|H silent|CAG>CAA|Q|218 SEC5 SECretory 971.0 0 0 0 0 0.9581582499215126 P89102 0.9570760130882264 0.1267118752002716 40.924107166267284 30.0 0.0 no 2134 chrIV_788579r 6555 essential YDR166C 620 + TTTCAAACTGAAACCGCTAA F|208|L silent|TTC>TTT|F|208 SEC5 SECretory 971.0 0 0 0 0 0.7629476064916063 P89102 0.9387490153312684 1.0 39.17721821868157 35.0 0.0 no 2135 chrIV_788702 6557 essential YDR166C 500 - CGTCAAATTCTTTGTAAATT D|173|H D|173|N SEC5 SECretory 971.0 0 0 0 0 0.5630768586489987 P89102 0.9486550092697144 0.956179976463318 35.57588917413216 25.0 0.0 no 2136 chrIV_788914 6559 essential YDR166C 288 - TTCAACCGCATTGAATCATT L|102|F silent|TTG>TTA|L|102 silent|CGG>CGC|R|101 silent|CGG>CGA|R|101 SEC5 SECretory 971.0 0 0 0 0 0.8642055412807608 P89102 0.9587849974632264 0.6958038210868835 43.335226567599754 35.0 0.0 no 2137 chrIV_788919r 6560 essential YDR166C 280 + ATCTACCAAATGATTCAATG L|95|V silent|CTA>TTA|L|95 P|96|A P|96|S SEC5 SECretory 971.0 0 0 0 0 0.36290246703121776 P89102 0.9512209892272948 0.9562489986419678 0.9498909711837769 0.4749771654605866 0.8437909483909607 0.8117083907127379 36.83272399139491 30.0 0.0 no 2138 chrIV_789509 6564 essential YDR167W 60 + ACACCTTTTCCATCGGTTGC P|22|A P|22|S T|21|R T|21|I TAF10 TATA binding protein-Associated Factor 206.0 0 0 0 0 -0.4760610772010215 Q12030 0.9922440052032472 1.018030047416687 0.9608430266380309 0.9708430171012878 0.3972179293632507 0.5470120310783386 54.9781092544053 50.0 1.0 no 2139 chrIV_789728 6571 essential YDR167W 279 + GACTACTATTTAACCAAAAA D|94|E silent|GAC>GAT|D|94 Y|95|* silent|TAC>TAT|Y|95 TAF10 TATA binding protein-Associated Factor 206.0 0 0 0 0 0.2508020026457388 Q12030 0.9110530018806458 0.014797024428844454 33.296323624126785 25.0 1.0 no 2140 chrIV_789741r 6572 essential YDR167W 295 - TGCTACGTTAAACCCGTTTT A|105|P A|105|T V|104|L V|104|I TAF10 TATA binding protein-Associated Factor 206.0 0 0 0 0 -0.3829352389305144 Q12030 0.9546470046043396 0.9561290144920348 0.9889580011367798 0.937261998653412 0.35578396916389465 0.5239954590797424 0.4730764627456665 0.4377643167972565 47.38989686576144 40.0 1.0 no 2141 chrIV_789868 6576 essential YDR167W 419 + ATCTAATGCTAACAACAGTC S|141|C S|141|F TAF10 TATA binding protein-Associated Factor 206.0 0 0 0 0 1.2714980106258211 Q12030 0.7603319883346558 0.8617920279502869 0.13374739885330197 0.2840738296508789 38.9577561567765 35.0 1.0 no 2142 chrIV_790394r 6579 essential YDR168W 69 - AACGATTTCTTGTCCACATT silent|TCG>TCC|S|29 silent|TCG>TCA|S|29 CDC37 Cell Division Cycle 506.0 0 0 0 0 0.2631199277201096 P06101 44.8379987055249 35.0 1.0 no 2143 chrIV_790640r 6584 essential YDR168W 315 - TCATTGTATGTTGCAATCTC E|112|Q E|112|K CDC37 Cell Division Cycle 506.0 0 0 0 0 -0.3242873488589817 P06101 0.1616690158843994 0.029561301693320274 43.68481128855946 35.0 1.0 no 2144 chrIV_790841 6587 essential YDR168W 513 + TCATCTGAAGACATTCATAC S|172|* S|172|L S|173|C S|173|F CDC37 Cell Division Cycle 506.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.7934042596780427 P06101 0.0606117844581604 0.0 0.0 39.372163043572705 35.0 1.0 no 2145 chrIV_790874 6588 essential YDR168W 546 + AGCTTTATGAACAAGCAAAA S|183|R silent|AGC>AGT|S|183 CDC37 Cell Division Cycle 506.0 0 1 0 0 0.3872067447530315 P06101 0.0 35.94483814788174 30.0 1.0 no 2146 chrIV_791150 6592 essential YDR168W 822 + GCCTTTGAGTATCAGTTACA silent|GCC>GCG|A|275 silent|GCC>GCT|A|275 A|275|G A|275|V CDC37 Cell Division Cycle 506.0 0 0 0 0 -0.8332135293976258 P06101 0.06235523149371147 0.038930598646402366 48.937894161511345 40.0 1.0 no 2147 chrIV_791151r 6593 essential YDR168W 826 - ACCATGTAACTGATACTCAA G|282|R G|282|S G|282|A G|282|D CDC37 Cell Division Cycle 506.0 0 0 0 0 0.1290464936323744 P06101 0.18519830703735352 0.4359804093837738 0.2549794912338257 0.974562644958496 41.354216809853256 35.0 1.0 no 2148 chrIV_791220r 6594 essential YDR168W 895 - GTCGTAGATTTCCTTAATGT D|305|H D|305|N CDC37 Cell Division Cycle 506.0 0 0 0 0 0.6678452373635897 P06101 0.04023418575525284 0.6637958288192749 45.08418962910866 35.0 1.0 no 2149 chrIV_791314 6595 essential YDR168W 986 + CTTCAACAAGGACAAGCCAA F|330|L silent|TTC>TTT|F|330 N|331|K silent|AAC>AAT|N|331 CDC37 Cell Division Cycle 506.0 0 0 0 0 0.4359191523981795 P06101 0.7531642317771912 0.793303370475769 43.65768970918776 45.0 1.0 no 2150 chrIV_797920r 6597 essential YDR170C 4280 + TCTTGAATCCTTACAATATA L|1428|V L|1428|F SEC7 SECretory 2009.0 0 0 0 0 0.8734884207980479 P11075 0.9512209892272948 0.9587849974632264 0.051829848438501365 1.0 37.652882113900255 25.0 0.0 no 2151 chrIV_798116 6599 essential YDR170C 4087 - TCTCATAGACAATTGACGCA M|1368|I M|1368|I R|1369|T R|1369|K SEC7 SECretory 2009.0 0 0 0 0 -0.24597672219699598 P11075 0.9553959965705872 0.9553959965705872 0.932735025882721 0.955805003643036 0.2898693084716797 0.2898693084716797 0.0 0.0 43.41861475373157 40.0 0.0 no 2152 chrIV_798375r 6605 essential YDR170C 3825 + ACCAAAAGTTCCGAGTTATC silent|ACC>ACG|T|1276 silent|ACC>ACT|T|1276 T|1276|S T|1276|I SEC7 SECretory 2009.0 0 0 0 0 0.5183598672715645 P11075 0.9491789937019348 0.9472420215606691 0.5044259428977966 0.008601357229053974 43.69739959837881 40.0 0.0 no 2153 chrIV_798410 6606 essential YDR170C 3793 - CATCAAAACGACTAATTCAC L|1270|F silent|TTG>TTA|L|1270 SEC7 SECretory 2009.0 0 0 0 0 -0.5974909168444996 P11075 0.9587849974632264 0.08609166741371155 35.44396484049417 35.0 0.0 no 2154 chrIV_798516r 6607 essential YDR170C 3684 + ACATCTTTCTTTGATGTTTG T|1229|R T|1229|I S|1230|C S|1230|F SEC7 SECretory 2009.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.5855203647936611 P11075 0.9476869702339172 0.9472420215606691 0.945252001285553 0.9294660091400146 0.3371811509132385 0.16740265488624573 0.12441658228635788 0.3058633506298065 41.688875481401574 30.0 0.0 no 2155 chrIV_798517r 6608 essential YDR170C 3683 + TACATCTTTCTTTGATGTTT T|1229|R T|1229|I S|1230|C S|1230|F SEC7 SECretory 2009.0 1 Series([], Name: modification, dtype: object) 0 0 0 1.0079302488151392 P11075 0.9476869702339172 0.9472420215606691 0.945252001285553 0.9294660091400146 0.3371811509132385 0.16740265488624573 0.12441658228635788 0.3058633506298065 41.08448533661965 25.0 0.0 no 2156 chrIV_798518r 6609 essential YDR170C 3682 + ATACATCTTTCTTTGATGTT T|1229|R T|1229|I S|1230|C S|1230|F SEC7 SECretory 2009.0 1 Series([], Name: modification, dtype: object) 0 0 0 1.4728161052462152 P11075 0.9476869702339172 0.9472420215606691 0.945252001285553 0.9294660091400146 0.3371811509132385 0.16740265488624573 0.12441658228635788 0.3058633506298065 40.81504801834126 25.0 0.0 no 2157 chrIV_798664r 6611 essential YDR170C 3536 + ATCGTGGAAGGACATTTTGC S|1180|W S|1180|L SEC7 SECretory 2009.0 0 0 0 0 0.5009037004293203 P11075 0.9288619756698608 0.9298099875450134 0.0011566783068701625 0.007352381013333797 45.87623548994952 45.0 0.0 no 2158 chrIV_798895 6616 essential YDR170C 3308 - TGTCATCATAATCCTTAAAT D|1109|H D|1109|N D|1108|H D|1108|N SEC7 SECretory 2009.0 0 1 0 0 0.9492777305058496 P11075 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.010032124817371368 0.03641276434063912 0.010795717127621174 0.15992684662342072 37.77640722550677 25.0 0.0 no 2159 chrIV_798907r 6620 essential YDR170C 3293 + AGCTCTAACCCCCCCATTTA A|1099|G A|1099|V L|1100|V silent|CTA>TTA|L|1100 SEC7 SECretory 2009.0 0 0 0 0 0.2908989203337309 P11075 0.9484469890594482 0.9504740238189696 0.9512209892272948 1.0 0.02425883151590824 0.0 59.09000293679957 50.0 0.0 no 2160 chrIV_798944r 6621 essential YDR170C 3256 + AATCAATTTTCGAGACACTA S|1087|* S|1087|L SEC7 SECretory 2009.0 0 0 0 0 0.17782362968288495 P11075 0.9298099875450134 0.17540757358074188 37.75432754473388 30.0 0.0 no 2161 chrIV_799221 6626 essential YDR170C 2982 - AAACCTTCCAAGAAGTCTCT G|1000|A G|1000|D G|1000|R G|1000|S SEC7 SECretory 2009.0 0 0 0 0 0.032056476578824336 P11075 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.7552211284637451 0.6262327432632446 0.5164671540260315 0.7222049832344055 -0.7380999922752379 -0.2506999969482422 -1.0278199911117554 0.1109599992632866 45.08927817697964 40.0 0.0 no 2162 chrIV_799378r 6630 essential YDR170C 2822 + AAACCCCGGAGTCTTTTCAA N|942|K silent|AAC>AAT|N|942 P|943|A P|943|S SEC7 SECretory 2009.0 0 0 0 0 -0.8855991047646448 P11075 0.9439849853515624 0.9562489986419678 0.9498909711837769 0.0 0.053939081728458405 0.10405319184064864 1.5937000513076782 1.131420016288757 1.2583400011062622 1.5206141471862793 1.8189344406127932 49.4742499324226 45.0 0.0 no 2163 chrIV_799610 6636 essential YDR170C 2593 - TTCTGTTTCTAATAACCACT E|871|Q E|871|K SEC7 SECretory 2009.0 0 0 0 0 0.2621054137792237 P11075 0.956179976463318 0.9475290179252625 0.16862893104553225 0.1342286914587021 0.10255999863147736 -0.3810400068759918 41.85104096764928 30.0 0.0 no 2164 chrIV_799748 6638 essential YDR170C 2455 - TTTCAAATTTTCAAATTGTG L|824|F silent|TTG>TTA|L|824 SEC7 SECretory 2009.0 0 0 0 0 0.4580877542840392 P11075 0.9587849974632264 0.14789101481437686 -0.0821399986743927 32.40808673634285 20.0 0.0 no 2165 chrIV_799930r 6640 essential YDR170C 2270 + AAACACACACACTGCTAATA N|758|K silent|AAC>AAT|N|758 T|759|R T|759|I SEC7 SECretory 2009.0 0 0 0 0 0.06081420860119169 P11075 0.9439849853515624 0.9476869702339172 0.9472420215606691 0.920942485332489 0.3983133137226105 0.1726597249507904 38.815497421627576 35.0 0.0 no 2166 chrIV_800230r 6644 essential YDR170C 1970 + CCCTGGAATGCCAAATGTAA P|658|R P|658|L P|658|A P|658|S SEC7 SECretory 2009.0 0 0 0 0 -1.3167617178837028 P11075 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.5668335556983948 0.29921409487724304 0.7973303794860841 1.0 46.70925283261357 45.0 0.0 no 2167 chrIV_800538 6648 essential YDR170C 1665 - AAGCACACACGCTCCTTTCC C|561|S C|561|Y silent|GTG>GTC|V|560 silent|GTG>GTA|V|560 SEC7 SECretory 2009.0 0 0 0 0 -0.17721386306314282 P11075 0.9421560168266296 0.9290120005607604 0.7742393016815186 0.1922169327735901 54.960318654391024 55.00000000000001 0.0 no 2168 chrIV_800725 6652 essential YDR170C 1478 - CATCTTTAACAGCTAGATCT D|499|H D|499|N SEC7 SECretory 2009.0 0 0 0 0 -0.4069368673790044 P11075 0.9486550092697144 0.956179976463318 0.0 0.0 42.51848776465096 35.0 0.0 no 2169 chrIV_800839r 6656 essential YDR170C 1361 + TTCTGAAAATGCAGAAACGC S|455|C S|455|F SEC7 SECretory 2009.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.861905931336499 P11075 0.945252001285553 0.9294660091400146 0.05710742250084878 0.05804279074072838 38.26013712166082 40.0 0.0 no 2170 chrIV_800997r 6657 essential YDR170C 1203 + TCGTTGAACCCATCCAATCA S|402|W S|402|L SEC7 SECretory 2009.0 0 0 0 0 -0.027963708385693908 P11075 0.9288619756698608 0.9298099875450134 0.0 0.0 49.78835469739101 45.0 0.0 no 2171 chrIV_801091r 6659 essential YDR170C 1109 + ATCTAGTTGCATTTTAGAAG S|371|C S|371|F SEC7 SECretory 2009.0 0 0 0 0 0.8144588212591941 P11075 0.945252001285553 0.9294660091400146 0.07163172215223312 0.11711645126342772 39.02287545787994 30.0 0.0 no 2172 chrIV_801121 6662 essential YDR170C 1082 - TAACGATTTGTAGTTCCACA V|367|L V|367|I SEC7 SECretory 2009.0 0 0 0 0 0.4285261715916631 P11075 0.9539830088615416 0.9574310183525084 0.059293977916240685 0.6287899613380432 43.295537981590364 35.0 0.0 no 2173 chrIV_801159r 6664 essential YDR170C 1041 + ACTATTTCAGACTGTTTTCA T|348|S T|348|I SEC7 SECretory 2009.0 0 0 0 0 0.7645243629403615 P11075 0.9491789937019348 0.9472420215606691 0.09790853410959244 0.15587899088859558 42.758857013205954 30.0 0.0 no 2174 chrIV_801228r 6666 essential YDR170C 972 + CAACGACAAGATGCTGCCGA R|326|G R|326|* Q|327|E Q|327|* SEC7 SECretory 2009.0 0 0 0 0 -1.7577895741247158 P11075 0.8994590044021606 0.9590039849281312 0.3692299723625183 1.0 48.2698593155435 55.00000000000001 0.0 no 2175 chrIV_801380r 6669 essential YDR170C 820 + TACTAGTATTCGAAGCACTA L|275|V silent|CTA>TTA|L|275 SEC7 SECretory 2009.0 0 0 0 0 -0.3185232679931048 P11075 0.9512209892272948 1.0 41.307550990136974 35.0 0.0 no 2176 chrIV_801409r 6671 essential YDR170C 791 + CACGAATAACCCACATTACG T|265|R T|265|M SEC7 SECretory 2009.0 0 0 0 0 0.2287221534572949 P11075 0.9476869702339172 0.9502379894256592 42.75060734219454 45.0 0.0 no 2177 chrIV_801830 6677 essential YDR170C 373 - ATCTTCCCCGTCTTCGGAAC D|131|H D|131|N E|130|Q E|130|K SEC7 SECretory 2009.0 0 0 0 0 -0.009660957891685692 P11075 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.10778465867042543 0.3527469933032989 0.5533202290534973 0.8667894005775452 55.7650468873066 55.00000000000001 0.0 no 2178 chrIV_801824 6678 essential YDR170C 379 - TTCAGAATCTTCCCCGTCTT E|133|Q E|133|K SEC7 SECretory 2009.0 0 0 0 0 0.3714491293955137 P11075 0.956179976463318 0.9475290179252625 0.3845341801643372 0.5052708387374878 53.826218982797634 45.0 0.0 no 2179 chrIV_801940 6681 essential YDR170C 263 - CATCTTCACCTTCATCGTCA D|94|H D|94|N E|93|Q E|93|K SEC7 SECretory 2009.0 0 0 0 0 -0.3589847892072047 P11075 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.0349215492606163 0.597148597240448 0.5177504420280457 0.8006688952445984 51.806409247193024 45.0 0.0 no 2180 chrIV_802104 6682 essential YDR170C 99 - TCTTCTTTAATAGCATTCTG E|40|Q E|40|K E|39|Q E|39|K SEC7 SECretory 2009.0 0 0 0 0 -2.095696787027568 P11075 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 40.86564830533945 30.0 0.0 yes 2181 chrIV_808433 6687 essential YDR172W 109 + CTCAAGCCCAACCTGCAGGT Q|38|E Q|38|* A|39|G A|39|V SUP35 SUPpressor 685.0 0 0 0 0 -0.7595863946125699 P05453 1.0024600028991701 0.9916989803314208 0.9909250140190125 58.42603893644269 60.0 1.0 no 2182 chrIV_808488r 6688 essential YDR172W 167 - ACTGTTGATAGCCACCTTGT Q|62|H silent|CAG>CAA|Q|62 SUP35 SUPpressor 685.0 0 0 0 0 -2.17835929590078 P05453 1.0016599893569946 52.86827057613744 45.0 1.0 yes 2183 chrIV_808504 6689 essential YDR172W 180 + CAACAGTACAATCCCGACGC Q|62|E Q|62|* SUP35 SUPpressor 685.0 0 0 0 0 -0.4589802702773307 P05453 1.0036499500274658 48.92259237748289 55.00000000000001 1.0 no 2184 chrIV_808531 6691 essential YDR172W 207 + CAGCAACAGTATAATCCTCA Q|71|E Q|71|* Q|72|E Q|72|* SUP35 SUPpressor 685.0 0 0 0 0 -0.32621457717612473 P05453 1.0036499500274658 1.0036499500274658 0.8344830870628357 0.9339277744293212 44.69315085174828 40.0 1.0 no 2185 chrIV_808558 6692 essential YDR172W 234 + TATCAACAGTACAATCCTCA Q|80|E Q|80|* Q|81|E Q|81|* SUP35 SUPpressor 685.0 0 0 0 0 -0.20272020903314064 P05453 1.0036499500274658 1.0036499500274658 0.4003121554851532 0.2360284924507141 42.43128994152386 35.0 1.0 no 2186 chrIV_808588 6698 essential YDR172W 264 + CAGCAGCAATTCAATCCACA Q|90|E Q|90|* Q|91|E Q|91|* SUP35 SUPpressor 685.0 0 0 0 0 -0.9223540150749926 P05453 1.0087000131607056 1.0087000131607056 1.0 0.9433793425559998 47.86989010230605 45.0 1.0 no 2187 chrIV_808787r 6700 essential YDR172W 466 - GCCAACCTTCTTGGTAGCAT G|162|R G|162|S G|162|A G|162|D SUP35 SUPpressor 685.0 0 0 0 0 0.4072776514109088 P05453 0.9727219939231871 0.9916149973869324 0.9903749823570251 0.9780880212783812 0.5170151591300964 0.7599600553512573 0.7532410621643066 0.6303210258483887 55.37609466263722 50.0 1.0 no 2188 chrIV_808859r 6704 essential YDR172W 538 - TGGCTCTTTAGTTGGTTCTT E|185|D silent|GAG>GAA|E|185 E|185|Q E|185|K SUP35 SUPpressor 685.0 0 0 0 0 -0.2191371874732583 P05453 0.9933249950408936 1.0004899501800537 0.9891330003738404 0.5978288054466248 0.5297496914863586 0.8340572118759155 51.757987212708095 40.0 1.0 no 2189 chrIV_809033r 6710 essential YDR172W 712 - TTCTTCCTGTTCCTTGATCA E|244|Q E|244|K E|243|Q E|243|K SUP35 SUPpressor 685.0 0 0 0 0 0.2470250862253683 P05453 0.9202449917793274 0.9081959724426271 0.9209830164909364 0.9089339971542358 0.4939343929290772 0.7706422805786133 0.5636264681816101 0.8518282771110535 52.906396289069725 40.0 1.0 no 2190 chrIV_809101 6711 essential YDR172W 777 + CACGTTTCTTTAATTTTCAT H|260|Q silent|CAC>CAT|H|260 SUP35 SUPpressor 685.0 0 0 0 0 0.42213802419350266 P05453 0.9229769706726074 0.005266496911644936 0.4465999901294708 39.59223647322432 25.0 1.0 no 2191 chrIV_809100 6712 essential YDR172W 776 + TCACGTTTCTTTAATTTTCA H|260|Q silent|CAC>CAT|H|260 H|260|D H|260|Y SUP35 SUPpressor 685.0 0 0 0 0 0.7681570596314484 P05453 0.9229769706726074 0.9115030169487 0.9116550087928772 0.005266496911644936 0.019763223826885223 0.03747321665287018 0.4465999901294708 1.125 -0.09239999949932097 40.49799114226949 25.0 1.0 no 2192 chrIV_809219r 6717 essential YDR172W 898 - ACCTTGTCTGCCTGCATCCT G|306|R G|306|S G|306|A G|306|D SUP35 SUPpressor 685.0 0 0 0 0 -0.7436846553455612 P05453 0.9563270211219788 0.9761779904365541 0.9749379754066468 0.9628639817237854 0.02506004460155964 1.0 0.1650175005197525 0.048117157071828835 -1.4606000185012815 -0.16699999570846558 -0.6284000277519226 -0.16459999978542328 62.187016182507314 55.00000000000001 1.0 no 2193 chrIV_809432r 6722 essential YDR172W 1111 - TTCGTACTCACCCTTTCTGG E|377|Q E|377|K E|375|D silent|GAG>GAA|E|375 SUP35 SUPpressor 685.0 0 0 0 0 -4.96661973337792 P05453 1.006500005722046 0.9951429963111876 0.999334990978241 0.0 0.0 0.0 2.711800098419189 2.804800033569336 1.606600046157837 -0.6424000263214111 53.97569006248648 50.0 1.0 yes 2194 chrIV_809730r 6732 essential YDR172W 1409 - CCAGATATTCTAACAGAGTT silent|CTG>CTC|L|476 silent|CTG>CTA|L|476 SUP35 SUPpressor 685.0 0 0 0 0 0.2533897314015712 P05453 41.9100715848432 35.0 1.0 no 2195 chrIV_809731r 6734 essential YDR172W 1410 - TCCAGATATTCTAACAGAGT silent|CTG>CTC|L|476 silent|CTG>CTA|L|476 D|477|H D|477|N SUP35 SUPpressor 685.0 0 0 0 0 0.4809710557705426 P05453 0.9202659726142884 0.9315000176429749 0.028871998190879825 0.032043714076280594 2.1157999038696294 -0.3043999969959259 10.16100025177002 -0.13379999995231628 42.61505899383246 35.0 1.0 no 2196 chrIV_809831r 6739 essential YDR172W 1510 - TTCAATTTTACCTTCAACGA E|510|Q E|510|K SUP35 SUPpressor 685.0 0 0 0 0 -0.6563700333152537 P05453 1.0002599954605105 0.9889079928398132 0.0 0.0 -1.2705999612808228 -1.007599949836731 40.77508305386869 30.0 1.0 no 2197 chrIV_810839r 6740 high_effect YDR173C 771 + AGTCTTTTGTTTATTTACGA L|259|V L|259|F ARG82 ARGinine requiring 355.0 0 0 0 0 0.8743625790313171 P07250 0.9410560131072998 0.8742089867591858 0.0 0.0 2.4149599075317383 8.180680274963379 40.535972285856815 25.0 0.0 no 2198 chrIV_810947 6742 high_effect YDR173C 666 - TTTCTCGCATCCGACAGATG R|228|T R|228|K silent|GCG>GCC|A|227 silent|GCG>GCA|A|227 ARG82 ARGinine requiring 355.0 0 0 0 0 -1.0380345487112144 P07250 0.9483450055122375 0.9721180200576782 0.2494338601827621 0.7937008142471313 1.4420599937438965 0.9309399724006652 49.79921285563052 50.0 0.0 no 2199 chrIV_811412 6748 high_effect YDR173C 201 - TTCAAGACTCCAAGATACGT L|73|F silent|TTG>TTA|L|73 ARG82 ARGinine requiring 355.0 0 0 0 0 -0.08115328579262901 P07250 0.8541949987411499 0.02947299741208553 0.4192399978637695 -0.8187999725341797 43.38175333658245 40.0 0.0 no 2200 chrIV_811421r 6749 high_effect YDR173C 189 + TCTTGGATGCCCACGTATCT S|64|C S|64|F ARG82 ARGinine requiring 355.0 0 0 0 0 -1.0764226190591923 P07250 0.9424830079078674 0.8615679740905762 0.18139694631099698 0.7015397548675537 0.534820020198822 0.0444599986076355 54.82380353120891 50.0 0.0 no 2201 chrIV_808386r 6750 essential YDR172W 65 - ATCTGTTGTTACCTTGTTGT R|28|T R|28|K SUP35 SUPpressor 685.0 0 0 0 0 1.016402471330952 P05453 0.9788659811019896 0.9986129999160768 49.10015375144246 35.0 1.0 no 2202 chrIV_811518r 6752 high_effect YDR173C 92 + ACCGGCCTTTCCGCAGGAAC P|32|R P|32|L P|32|A P|32|S ARG82 ARGinine requiring 355.0 0 0 0 0 -1.1111175703620149 P07250 0.8383769989013672 0.936303973197937 0.9561960101127625 0.9417170286178588 0.11323852837085725 0.8719272017478943 0.3620106279850006 0.18335826694965365 1.4562599658966064 1.4420599937438965 1.4689999818801882 2.26557993888855 59.055453503376434 65.0 0.0 no 2203 chrIV_813524r 6755 high_effect YDR175C 606 + AGCGTTAAAACCAAGGAATT S|203|R silent|AGC>AGT|S|203 RSM24 Ribosomal Small subunit of Mitochondria 319.0 0 0 0 0 -0.9645313674255768 Q03976 0.9417110085487366 0.050192147493362434 39.06623927983468 35.0 0.0 no 2204 chrIV_813525r 6756 high_effect YDR175C 605 + AAGCGTTAAAACCAAGGAAT S|203|R silent|AGC>AGT|S|203 RSM24 Ribosomal Small subunit of Mitochondria 319.0 0 0 0 0 0.5409885008434394 Q03976 0.9417110085487366 0.050192147493362434 37.669769664791374 35.0 0.0 no 2205 chrIV_813559r 6757 high_effect YDR175C 571 + GCGAAGAGCATCCCAATTCG silent|GGC>GGG|G|191 silent|GGC>GGT|G|191 RSM24 Ribosomal Small subunit of Mitochondria 319.0 0 0 0 0 -0.6808166345059525 Q03976 50.381946611670344 55.00000000000001 0.0 no 2206 chrIV_813609r 6759 high_effect YDR175C 521 + ACCATCTCCAGAAAGTCATC P|175|R P|175|L P|175|A P|175|S RSM24 Ribosomal Small subunit of Mitochondria 319.0 0 0 0 0 -0.14434327434879846 Q03976 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.36063602566719055 0.16709744930267334 0.1809045970439911 0.11429187655448915 47.886093393626034 45.0 0.0 no 2207 chrIV_813833 6766 high_effect YDR175C 300 - AGCTTTTTAATATCGTTAAC K|106|N silent|AAG>AAA|K|106 RSM24 Ribosomal Small subunit of Mitochondria 319.0 0 0 0 0 0.7253303098742301 Q03976 0.9355990290641784 0.3719035387039185 36.643509915527375 25.0 0.0 no 2208 chrIV_814077 6769 high_effect YDR175C 56 - ACATTGTCAAAACCCTTTTC M|25|I M|25|I RSM24 Ribosomal Small subunit of Mitochondria 319.0 0 0 0 0 -0.7854154974670179 Q03976 0.9553959965705872 0.9553959965705872 0.5002579689025879 0.5002579689025879 43.2768776330829 35.0 0.0 no 2209 chrIV_814591 6772 high_effect YDR176W 139 + TGCTCAATGGCAAAAGTGTT L|48|V L|48|F silent|CTC>CTG|L|48 silent|CTC>CTT|L|48 NGG1 702.0 0 1 0 0 0.6530222977823185 P32494 0.9512209892272948 0.9587849974632264 0.0 0.0 43.64688650795984 40.0 1.0 no 2210 chrIV_814822 6775 high_effect YDR176W 370 + AAACGAATATAATTGATAAA T|125|R T|125|M NGG1 702.0 0 0 0 0 0.8809477881312087 P32494 0.9476869702339172 0.9502379894256592 0.4694175124168396 0.09603605419397354 26.304130472309513 15.0 1.0 no 2211 chrIV_814885r 6780 high_effect YDR176W 436 - TACATCGTTCTCAATTGTGC V|152|L V|152|I D|151|H D|151|N NGG1 702.0 0 1 0 0 -0.7362196755215605 P32494 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 0.31468501687049866 0.19838573038578036 0.04986131936311722 0.6308660507202148 45.450712798643906 40.0 1.0 no 2212 chrIV_815438 6785 high_effect YDR176W 986 + TGACAAAACTTATGACCCTG D|330|E silent|GAC>GAT|D|330 NGG1 702.0 0 0 0 0 0.2793557904455153 P32494 0.9532920122146606 0.2427761852741241 41.1432017694857 40.0 1.0 no 2213 chrIV_815466 6786 high_effect YDR176W 1014 + CCGTTTATTATACCGAAACT P|339|R P|339|L NGG1 702.0 0 0 0 0 -0.8252995750741496 P32494 0.9432820081710817 0.9430609941482544 0.0 0.0 42.20805893675009 35.0 1.0 no 2214 chrIV_815599r 6788 high_effect YDR176W 1150 - AGCATTATCATCAAGTTCGT A|390|P A|390|T NGG1 702.0 0 0 0 0 0.7980796551005312 P32494 0.9573720097541808 0.9523990154266356 0.06956261396408081 0.3077387511730194 44.602075965584724 35.0 1.0 no 2215 chrIV_815650r 6791 high_effect YDR176W 1201 - ACTCAACAGCCTAGATAATA L|406|F silent|TTG>TTA|L|406 S|407|T S|407|N NGG1 702.0 0 1 0 0 0.4252071081474901 P32494 0.9587849974632264 0.9512869715690612 0.9536849856376648 0.0 0.028721421957015988 0.009303723461925985 41.56994526280785 35.0 1.0 no 2216 chrIV_815707 6792 high_effect YDR176W 1255 + TGCAATCTTCTAAAATAATA Q|420|E Q|420|* S|421|C S|421|F NGG1 702.0 0 0 0 0 1.2859846542577709 P32494 0.9590039849281312 0.945252001285553 0.9294660091400146 1.0 0.06927561014890671 0.12265577167272568 31.849232935391054 20.0 1.0 no 2217 chrIV_815712 6793 high_effect YDR176W 1260 + TCTTCTAAAATAATACGGGA S|421|C S|421|F S|422|C S|422|F NGG1 702.0 0 0 0 0 -2.266747441692272 P32494 0.945252001285553 0.9294660091400146 0.945252001285553 0.9294660091400146 0.06927561014890671 0.12265577167272568 0.07523301988840103 0.06305311620235443 35.8633679905974 30.0 1.0 yes 2218 chrIV_815742r 6797 high_effect YDR176W 1293 - TCGTCTTCCCCTCCGGTTCT D|438|H D|438|N D|437|H D|437|N NGG1 702.0 0 1 0 0 -0.917774769294662 P32494 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.12328611314296722 0.9915645122528076 0.13331177830696106 0.4880149662494659 65.25441227530628 60.0 1.0 no 2219 chrIV_815976r 6803 high_effect YDR176W 1527 - TTCAATCGTTCTTCGAATGT L|515|F silent|TTG>TTA|L|515 R|514|P R|514|Q NGG1 702.0 0 0 0 0 -0.09562055274630443 P32494 0.9587849974632264 0.9099509716033936 0.949662983417511 0.0 0.0 0.0 42.77807242758769 35.0 1.0 no 2220 chrIV_816965 6805 essential YDR177W 87 + TCTGATATCCACCATTTAAA S|30|C S|30|F UBC1 UBiquitin-Conjugating 215.0 0 0 0 0 -0.3899298677991632 P21734 0.934786021709442 0.9174950122833252 0.044109955430030816 0.035487040877342224 0.31700000166893005 -0.16920000314712524 41.51046082997789 30.0 1.0 no 2221 chrIV_816976 6806 essential YDR177W 98 + CCATTTAAAAGGCACATTTT H|34|D H|34|Y UBC1 UBiquitin-Conjugating 215.0 0 0 0 0 0.4492028701981141 P21734 0.9439060091972352 0.9440569877624512 0.009329956024885178 0.012570181861519814 0.1534000039100647 -1.1543999910354614 2.231100082397461 -0.4541000127792358 40.0981584282502 30.0 1.0 no 2222 chrIV_816976r 6808 essential YDR177W 101 - CCAAAAATGTGCCTTTTAAA L|40|F silent|TTG>TTA|L|40 UBC1 UBiquitin-Conjugating 215.0 0 0 0 0 0.7268919581536558 P21734 0.9559940099716188 0.3925141990184784 -0.14419999718666074 1.8559199571609497 38.29791627012026 30.0 1.0 no 2223 chrIV_817000r 6810 essential YDR177W 125 - CCTCGTAAGGTGTTCCAGGT E|48|Q E|48|K E|48|D silent|GAG>GAA|E|48 UBC1 UBiquitin-Conjugating 215.0 0 1 0 0 -1.7755897872302833 P21734 0.9594100117683412 0.9491919875144958 0.9537240266799928 0.17319966852664948 0.11331544071435927 0.2503194212913513 -1.791800022125244 -1.358199954032898 0.13920000195503235 56.80229082152545 55.00000000000001 1.0 no 2224 chrIV_817013r 6812 essential YDR177W 138 - ACAAATTTGCCACCCTCGTA V|53|L V|53|I UBC1 UBiquitin-Conjugating 215.0 0 0 0 0 -0.1331997287650065 P21734 0.9454690217971802 0.9546409845352172 0.28845328092575073 0.18690082430839536 -0.2702000141143799 -0.5690000057220459 0.1412000060081482 -0.32513999938964844 50.775872166737436 45.0 1.0 no 2225 chrIV_817319 6819 essential YDR177W 441 + TACGCCAGTGAAACTTCCAA Y|148|* silent|TAC>TAT|Y|148 A|149|G A|149|V UBC1 UBiquitin-Conjugating 215.0 0 0 0 0 -0.3410762421015319 P21734 0.9109870195388794 0.9102140069007874 0.0 0.0 0.8230000138282776 1.6075999736785889 46.81883463161285 45.0 1.0 no 2226 chrIV_821376r 6823 essential YDR180W 84 - AGCGCGGCTAACCCATCCTT silent|GCG>GCC|A|34 silent|GCG>GCA|A|34 A|34|P A|34|T SCC2 Sister Chromatid Cohesion 1493.0 0 0 0 0 -0.17334884218142854 Q04002 0.9573720097541808 0.9523990154266356 0.21995261311531067 0.6140933036804199 0.19088000059127808 0.09837999939918518 59.645805743665676 60.0 1.0 no 2227 chrIV_821395 6825 essential YDR180W 100 + CGCTAGTAAATGCCCCAATG L|35|V silent|CTA>TTA|L|35 SCC2 Sister Chromatid Cohesion 1493.0 0 0 0 0 1.0628963289979267 Q04002 0.9512209892272948 0.06097854673862457 1.1358599662780762 48.752160791234814 50.0 1.0 no 2228 chrIV_821712r 6832 essential YDR180W 420 - TCGAGCTTATGCTTTGCCTC E|147|Q E|147|K K|145|N silent|AAG>AAA|K|145 SCC2 Sister Chromatid Cohesion 1493.0 0 0 0 0 0.20216977882095927 Q04002 0.956179976463318 0.9475290179252625 0.9355990290641784 0.10027873516082764 0.2329594194889069 0.12257559597492218 54.405341411372824 50.0 1.0 no 2229 chrIV_822009r 6835 essential YDR180W 717 - TCGATTGAGTTCGATAGCTG E|246|Q E|246|K SCC2 Sister Chromatid Cohesion 1493.0 0 0 0 0 0.21400450802283064 Q04002 0.956179976463318 0.9475290179252625 0.26680457592010504 0.4648698568344116 45.349634917059234 45.0 1.0 no 2230 chrIV_822327 6836 essential YDR180W 1032 + CTACCGAAATACATACGTAA P|346|A P|346|S P|346|R P|346|L SCC2 Sister Chromatid Cohesion 1493.0 0 0 0 0 -0.2980871779819002 Q04002 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.0 0.0 0.0 0.0 37.988838457090075 35.0 1.0 no 2231 chrIV_822440r 6838 essential YDR180W 1148 - TATCCCAAAAACTTTGAAAT D|389|H D|389|N W|388|C W|388|* SCC2 Sister Chromatid Cohesion 1493.0 0 0 0 0 1.7371665412185944 Q04002 0.9486550092697144 0.956179976463318 0.8858469724655151 0.09308652579784392 0.13814517855644226 0.0224491935223341 35.0967366656692 25.0 1.0 no 2232 chrIV_822608r 6839 essential YDR180W 1316 - AATCAGTGATATAAATGTTT D|445|H D|445|N SCC2 Sister Chromatid Cohesion 1493.0 0 0 0 0 1.1930432552214931 Q04002 0.9486550092697144 0.956179976463318 0.14470690488815308 0.06756020337343216 32.85922486113162 20.0 1.0 no 2233 chrIV_822805 6842 essential YDR180W 1510 + TCAAGAACCCGTCCGCTTTA F|504|L silent|TTC>TTT|F|504 SCC2 Sister Chromatid Cohesion 1493.0 0 1 0 0 0.2977060088019615 Q04002 0.9387490153312684 1.0 52.30895109965167 50.0 1.0 no 2234 chrIV_822812r 6843 essential YDR180W 1520 - TTACATACCTTAAAGCGGAC V|513|L V|513|I SCC2 Sister Chromatid Cohesion 1493.0 0 0 0 0 0.6479137469432279 Q04002 0.9539830088615416 0.9574310183525084 0.1613619327545166 0.4464624524116516 42.110194381295905 40.0 1.0 no 2235 chrIV_822817r 6844 essential YDR180W 1525 - GTCAATTACATACCTTAAAG D|515|H D|515|N SCC2 Sister Chromatid Cohesion 1493.0 0 0 0 0 -1.7498193446874837 Q04002 0.9486550092697144 0.956179976463318 0.024186275899410248 0.07309260964393616 36.63499793570378 30.0 1.0 no 2236 chrIV_822862 6845 essential YDR180W 1567 + TGCTAATTTCCTCCCCTCAG L|524|V silent|CTA>TTA|L|524 SCC2 Sister Chromatid Cohesion 1493.0 0 0 0 0 0.18947151254952324 Q04002 0.9512209892272948 0.04139586165547371 56.256528055036476 50.0 1.0 no 2237 chrIV_822875r 6847 essential YDR180W 1583 - TTTCTGTTACAGGCCACTGA E|534|Q E|534|K SCC2 Sister Chromatid Cohesion 1493.0 0 0 0 0 -1.6170199558738203 Q04002 0.956179976463318 0.9475290179252625 0.4098182022571564 0.329061359167099 51.53549084877256 45.0 1.0 no 2238 chrIV_822972 6849 essential YDR180W 1677 + ACAATATGTTTACAACTTAT T|560|R T|560|I SCC2 Sister Chromatid Cohesion 1493.0 0 0 0 0 0.5337877810506878 Q04002 0.9476869702339172 0.9472420215606691 0.0934119150042534 0.06036306545138359 33.92336840526747 20.0 1.0 no 2239 chrIV_823150 6850 essential YDR180W 1855 + GTTCTGCAACAAGATTCCTT S|620|C S|620|F A|621|G A|621|V SCC2 Sister Chromatid Cohesion 1493.0 0 0 0 0 0.5505133504130104 Q04002 0.945252001285553 0.9294660091400146 0.9484469890594482 0.9504740238189696 0.17508183419704434 0.7094928622245789 0.7303488254547119 0.40993690490722656 46.934037843284436 40.0 1.0 no 2240 chrIV_823296r 6851 essential YDR180W 2004 - GCTTCTCTGTTCTCTAATTC A|675|P A|675|T E|674|Q E|674|K SCC2 Sister Chromatid Cohesion 1493.0 0 0 0 0 0.2758200919370091 Q04002 0.9573720097541808 0.9523990154266356 0.956179976463318 0.9475290179252625 0.3426539599895477 0.6786562204360962 0.4323955178260803 1.0 48.568435132651814 40.0 1.0 no 2241 chrIV_823297r 6852 essential YDR180W 2005 - TGCTTCTCTGTTCTCTAATT A|675|P A|675|T E|674|Q E|674|K SCC2 Sister Chromatid Cohesion 1493.0 0 0 0 0 -0.004969175224627226 Q04002 0.9573720097541808 0.9523990154266356 0.956179976463318 0.9475290179252625 0.3426539599895477 0.6786562204360962 0.4323955178260803 1.0 47.37342821225195 35.0 1.0 no 2242 chrIV_823420r 6853 essential YDR180W 2128 - TCTCAGTTTGATTTTATCCT silent|CTG>CTC|L|715 silent|CTG>CTA|L|715 R|716|T R|716|K SCC2 Sister Chromatid Cohesion 1493.0 0 0 0 0 0.8043176122634792 Q04002 0.932735025882721 0.955805003643036 0.01786548085510731 0.3609333336353302 45.57956126247484 30.0 1.0 no 2243 chrIV_823538 6854 essential YDR180W 2243 + CGACTCATCTGCATCTGTCA D|749|E silent|GAC>GAT|D|749 S|750|* S|750|L SCC2 Sister Chromatid Cohesion 1493.0 0 0 0 0 0.5131267443352869 Q04002 0.9532920122146606 0.9298099875450134 0.0393419973552227 0.020276941359043118 51.841831277443646 50.0 1.0 no 2244 chrIV_823736r 6856 essential YDR180W 2444 - CCTCGTCTTCTATTTTCATT E|821|Q E|821|K E|821|D silent|GAG>GAA|E|821 SCC2 Sister Chromatid Cohesion 1493.0 0 0 0 0 -0.5132419431757002 Q04002 0.956179976463318 0.9475290179252625 0.94931298494339 0.0 0.0 0.0 48.444604266291606 35.0 1.0 no 2245 chrIV_823883r 6862 essential YDR180W 2591 - TCTCATTCATTATAGCCACA E|870|Q E|870|K E|870|D silent|GAG>GAA|E|870 SCC2 Sister Chromatid Cohesion 1493.0 0 0 0 0 0.08588439594467115 Q04002 0.956179976463318 0.9475290179252625 0.94931298494339 0.40974068641662603 0.5097437500953674 0.37926185131073 46.73285916855178 35.0 1.0 no 2246 chrIV_824099r 6863 essential YDR180W 2807 - AATCAGCAAACTTCGCCAAA D|942|H D|942|N A|941|P A|941|T SCC2 Sister Chromatid Cohesion 1493.0 0 0 0 0 1.3817620391628662 Q04002 0.9486550092697144 0.956179976463318 0.9573720097541808 0.9523990154266356 0.040252119302749634 0.18022993206977844 0.04480089992284775 0.0583035983145237 42.736918699163034 40.0 1.0 no 2247 chrIV_824153 6864 essential YDR180W 2858 + TACAGCATTGTATCCTTATA T|954|R T|954|I A|955|G A|955|V SCC2 Sister Chromatid Cohesion 1493.0 0 0 0 0 0.2576637725785733 Q04002 0.9476869702339172 0.9472420215606691 0.9484469890594482 0.9504740238189696 0.2367487847805023 0.4345093071460724 0.2728613615036011 0.033110104501247406 43.43910664921618 30.0 1.0 no 2248 chrIV_824301r 6866 essential YDR180W 3009 - ATCTCTCTTACATTCATCTT E|1009|D silent|GAG>GAA|E|1009 E|1009|Q E|1009|K SCC2 Sister Chromatid Cohesion 1493.0 0 0 0 0 -0.0056073725631874405 Q04002 0.94931298494339 0.956179976463318 0.9475290179252625 0.0 0.0 0.0 44.72327553101576 30.0 1.0 no 2249 chrIV_824594r 6870 essential YDR180W 3302 - TGTCTTTAGATAGTACAAGT D|1107|H D|1107|N SCC2 Sister Chromatid Cohesion 1493.0 0 0 0 0 0.4724024046054274 Q04002 0.9486550092697144 0.956179976463318 0.11040789633989334 0.500404953956604 39.68166956076408 30.0 1.0 no 2250 chrIV_827623 6871 essential YDR182W 41 + CAGCAAGAAGAGCGACGATA S|15|R silent|AGC>AGT|S|15 CDC1 Cell Division Cycle 491.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.3313692034629321 P40986 43.636457138786284 50.0 1.0 no 2251 chrIV_827721 6872 essential YDR182W 139 + TATCTATTGTATGGATCTTA S|48|C S|48|F CDC1 Cell Division Cycle 491.0 0 0 0 0 0.4425289484250597 P40986 0.13839545845985413 0.3430798649787903 38.90220556999782 25.0 1.0 no 2252 chrIV_827941r 6880 essential YDR182W 362 - TCCAATTTCTCCTGTGATAA W|127|S W|127|* W|127|C W|127|* CDC1 Cell Division Cycle 491.0 0 0 0 0 0.7780311714496891 P40986 0.11989270150661467 0.052922170609235764 45.443200112595655 35.0 1.0 no 2253 chrIV_828085r 6882 essential YDR182W 506 - TTCTTCTCAGTGGCTTCTTG R|175|T R|175|K R|174|T R|174|K CDC1 Cell Division Cycle 491.0 0 0 0 0 1.1885662872494462 P40986 0.1397443413734436 0.9732349514961244 0.416945606470108 0.994674801826477 52.319368655641135 45.0 1.0 no 2254 chrIV_828122r 6883 essential YDR182W 543 - AAACCAATATCGTGATTACC G|187|A G|187|D G|187|R G|187|S CDC1 Cell Division Cycle 491.0 0 1 0 0 -0.758071356842083 P40986 0.0 0.0 0.0 0.0 40.15138853230764 35.0 1.0 no 2255 chrIV_828268 6887 essential YDR182W 686 + AACAAATCCGAATGTCTCGA T|230|R T|230|I CDC1 Cell Division Cycle 491.0 0 0 0 0 0.20159528546558256 P40986 0.37901726365089417 0.13565798103809354 41.34547679267529 40.0 1.0 no 2256 chrIV_828416 6891 essential YDR182W 834 + GAACCTTTTCCTATTCAGAA P|280|A P|280|S P|280|R P|280|L CDC1 Cell Division Cycle 491.0 0 0 0 0 1.0090698752815341 P40986 0.22602206468582156 0.19412685930728912 0.8227097392082214 0.1923273354768753 44.210136167319384 35.0 1.0 no 2257 chrIV_828448r 6893 essential YDR182W 869 - TATCGTTTTCTATAACTGTC D|296|H D|296|N CDC1 Cell Division Cycle 491.0 0 0 0 0 0.0014388571867418527 P40986 0.06819374114274979 0.2055831253528595 39.93686703557681 30.0 1.0 no 2258 chrIV_828545 6896 essential YDR182W 963 + TCACACTCATATCCGTTTCA H|323|D H|323|Y S|322|* S|322|L CDC1 Cell Division Cycle 491.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.7614830866343112 P40986 0.057974759489297874 0.02323699183762073 0.30460667610168457 48.74568784831222 40.0 1.0 no 2259 chrIV_828544 6897 essential YDR182W 962 + ATCACACTCATATCCGTTTC S|322|* S|322|L H|323|D H|323|Y CDC1 Cell Division Cycle 491.0 0 1 0 0 -0.06290078028801123 P40986 0.30460667610168457 0.057974759489297874 0.02323699183762073 47.4346327332018 40.0 1.0 no 2260 chrIV_836442r 6900 essential YDR188W 24 - CTTCTCAACGATTCAGCCTT R|14|T R|14|K L|13|F silent|TTG>TTA|L|13 CCT6 Chaperonin Containing TCP-1 546.0 0 1 0 0 0.16519647254782235 P39079 0.00852489285171032 0.08360737562179565 0.2573020160198212 1.6085000038146973 49.8911425779981 45.0 1.0 no 2261 chrIV_836534r 6902 essential YDR188W 116 - GCATCTTTAGCGTGCCCTTA M|45|I M|45|I K|44|N silent|AAG>AAA|K|44 CCT6 Chaperonin Containing TCP-1 546.0 0 1 0 0 -0.5274723877444412 P39079 0.08825784921646118 0.08825784921646118 0.002902171807363629 57.3487312157235 50.0 1.0 no 2262 chrIV_836587r 6904 essential YDR188W 169 - CAGCAACACTTTACCGTCCT L|62|F silent|TTG>TTA|L|62 silent|GTG>GTC|V|61 silent|GTG>GTA|V|61 CCT6 Chaperonin Containing TCP-1 546.0 0 1 0 0 -1.1131244948359036 P39079 0.010902578942477705 52.328558922835434 50.0 1.0 no 2263 chrIV_836692r 6913 essential YDR188W 274 - CACAAGACACACAACCGTCG V|98|L V|98|M CCT6 Chaperonin Containing TCP-1 546.0 0 0 0 0 -1.0397235469489847 P39079 0.3396585285663605 0.01676412113010883 45.88598691305452 55.00000000000001 1.0 no 2264 chrIV_836732 6918 essential YDR188W 311 + AGCGCACCGTTTCATTCAAG A|105|G A|105|V H|106|D H|106|Y CCT6 Chaperonin Containing TCP-1 546.0 0 0 0 0 0.16735641206539795 P39079 0.025058018043637283 0.3229571282863617 0.5520843863487244 0.0037266791332513094 1.565999984741211 -1.8912999629974363 50.796111709695985 50.0 1.0 no 2265 chrIV_836935r 6925 essential YDR188W 517 - TAGCACCGCATCCGTTACAA silent|GTG>GTC|V|178 silent|GTG>GTA|V|178 V|178|L V|178|M CCT6 Chaperonin Containing TCP-1 546.0 0 0 0 0 1.438273714056112 P39079 0.05999983102083206 0.006169974338263272 52.02272376280695 50.0 1.0 no 2266 chrIV_837098r 6933 essential YDR188W 680 - AAACATACGCGTTCTTCACA V|233|L V|233|I CCT6 Chaperonin Containing TCP-1 546.0 0 0 0 0 1.0112463356633974 P39079 0.01353358943015337 1.0 43.902697679949426 40.0 1.0 no 2267 chrIV_837097r 6934 essential YDR188W 679 - AACATACGCGTTCTTCACAC V|233|L V|233|I silent|GCG>GCC|A|231 silent|GCG>GCA|A|231 CCT6 Chaperonin Containing TCP-1 546.0 0 0 0 0 0.4651743273492158 P39079 0.01353358943015337 1.0 45.76107081411079 45.0 1.0 no 2268 chrIV_837208r 6939 essential YDR188W 790 - CACAAACTTCCTCTCACTAG V|270|L V|270|M K|268|N silent|AAG>AAA|K|268 CCT6 Chaperonin Containing TCP-1 546.0 0 0 0 0 -0.4150881686115914 P39079 0.27994051575660706 0.03255332261323929 0.04257628694176674 45.293716496358506 45.0 1.0 no 2269 chrIV_837255 6940 essential YDR188W 834 + GACTTGAAAAACGAAGTTTG D|279|E silent|GAC>GAT|D|279 CCT6 Chaperonin Containing TCP-1 546.0 0 0 0 0 -0.6296650729362435 P39079 1.0 33.938229032908 35.0 1.0 no 2270 chrIV_837235r 6941 essential YDR188W 817 - GTCGATGATCTTCTTCAACT D|279|H D|279|N CCT6 Chaperonin Containing TCP-1 546.0 0 0 0 0 0.05201197949765185 P39079 0.01140509732067585 0.03821093961596489 45.56162640548547 40.0 1.0 no 2271 chrIV_837356 6945 essential YDR188W 935 + CAACATCTTGGCTTTGAGAA N|313|K silent|AAC>AAT|N|313 I|314|M silent|ATC>ATT|I|314 CCT6 Chaperonin Containing TCP-1 546.0 0 1 0 0 0.2518361356904196 P39079 0.0818222314119339 0.0021520026493817568 43.203111188444154 40.0 1.0 no 2272 chrIV_837445 6946 essential YDR188W 1024 + ACTTGTCGCCTCAGATTCTT D|342|E silent|GAC>GAT|D|342 S|344|W S|344|L CCT6 Chaperonin Containing TCP-1 546.0 0 0 0 0 -0.6668440241357723 P39079 0.17311005294322968 0.009529784321784971 0.16004009544849396 53.018360853064564 45.0 1.0 no 2273 chrIV_837542 6951 essential YDR188W 1121 + GTCTTGCACCATCTTAATCA S|375|C S|375|F C|376|W silent|TGC>TGT|C|376 CCT6 Chaperonin Containing TCP-1 546.0 0 0 0 0 0.2812314236901633 P39079 0.0025145690888166428 0.0031738497782498602 0.014569087885320188 48.77447408952014 40.0 1.0 no 2274 chrIV_837581r 6953 essential YDR188W 1163 - CCGCATCCTTTGTTTGAGCG A|394|P A|394|T silent|GCG>GCC|A|394 silent|GCG>GCA|A|394 CCT6 Chaperonin Containing TCP-1 546.0 0 1 0 0 1.1361638827640452 P39079 0.01096981018781662 0.18436096608638766 55.030321221450265 55.00000000000001 1.0 no 2275 chrIV_838415r 6959 essential YDR189W 26 - CTCTTAAACTAATGTCCTTG R|15|T R|15|K SLY1 Suppressor of Loss of Ypt1 666.0 0 0 0 0 -1.0475218177334569 P22213 0.9114800095558168 0.9298490285873412 0.017266944050788883 0.24820618331432345 40.242963051320096 35.0 1.0 no 2276 chrIV_838414r 6960 essential YDR189W 25 - TCTTAAACTAATGTCCTTGC R|15|T R|15|K SLY1 Suppressor of Loss of Ypt1 666.0 0 0 0 0 -1.2388023718892136 P22213 0.9114800095558168 0.9298490285873412 0.017266944050788883 0.24820618331432345 41.9951526179841 35.0 1.0 no 2277 chrIV_838517 6961 essential YDR189W 125 + AGACGATATTTTTAACCAGC D|43|E silent|GAC>GAT|D|43 SLY1 Suppressor of Loss of Ypt1 666.0 0 0 0 0 0.568047541769221 P22213 0.9954699873924256 1.0 -0.37619999051094055 41.26182636773626 35.0 1.0 no 2278 chrIV_838532r 6963 essential YDR189W 143 - CCTTCCAGATGATCTCCTGC K|54|N silent|AAG>AAA|K|54 W|53|C W|53|* SLY1 Suppressor of Loss of Ypt1 666.0 0 0 0 0 -2.1691729938574587 P22213 0.9806249737739564 0.8764719963073729 0.0 0.0 5.1697998046875 57.05067745156748 55.00000000000001 1.0 yes 2279 chrIV_838700r 6967 essential YDR189W 311 - TGTCAATGTTTTCCTTTGTG D|110|H D|110|N SLY1 Suppressor of Loss of Ypt1 666.0 0 0 0 0 0.7866857400527812 P22213 0.974511981010437 0.9857460260391236 0.09628711640834807 0.3872338533401489 45.54644401797924 35.0 1.0 no 2280 chrIV_838943r 6972 essential YDR189W 554 - TTTCCTCTTCTGTGGTTTTC E|191|Q E|191|K E|190|D silent|GAG>GAA|E|190 SLY1 Suppressor of Loss of Ypt1 666.0 0 0 0 0 -0.4380368818010401 P22213 0.9857460260391236 0.9736970067024232 0.9692980051040648 0.5757126212120056 0.8417386412620544 0.5786899924278259 52.381374601966506 40.0 1.0 no 2281 chrIV_839031 6975 essential YDR189W 639 + CCCATTATAAGAGCAGCTAA silent|CCC>CCG|P|214 silent|CCC>CCT|P|214 P|214|R P|214|L SLY1 Suppressor of Loss of Ypt1 666.0 0 0 0 0 0.2959950599251364 P22213 0.9753050208091736 0.9834169745445251 0.0 0.0 45.55737301327798 40.0 1.0 no 2282 chrIV_839030r 6976 essential YDR189W 641 - CCTTAGCTGCTCTTATAATG K|220|N silent|AAG>AAA|K|220 A|219|P A|219|T SLY1 Suppressor of Loss of Ypt1 666.0 0 0 0 0 -1.3745259921989454 P22213 0.9665650129318236 0.9846779704093932 0.97638601064682 0.2247634679079056 1.0 0.4985835552215576 46.0297471949375 40.0 1.0 no 2283 chrIV_839058r 6977 essential YDR189W 669 - TTCTCAGCGATGATCTCAGC E|229|D silent|GAG>GAA|E|229 E|229|Q E|229|K SLY1 Suppressor of Loss of Ypt1 666.0 0 0 0 0 -0.18467754397784145 P22213 0.9761919975280762 0.9840490221977234 0.972000002861023 0.3976978361606598 1.0 0.975681483745575 51.10376612610554 50.0 1.0 no 2284 chrIV_839124 6978 essential YDR189W 732 + TCCTCCACTTCCACTTTGCA silent|TCC>TCG|S|245 silent|TCC>TCT|S|245 S|245|C S|245|F SLY1 Suppressor of Loss of Ypt1 666.0 0 0 0 0 -0.9749339908290668 P22213 0.9634199738502502 0.9436050057411194 0.12001176178455353 0.3820003271102905 58.530103422920554 50.0 1.0 no 2285 chrIV_839206r 6979 essential YDR189W 817 - AATCCACGAATGTGAAAACA W|278|C W|278|* W|278|S W|278|* SLY1 Suppressor of Loss of Ypt1 666.0 0 0 0 0 0.022940450507623042 P22213 0.8764719963073729 0.8762000203132629 0.02125093527138233 0.1932092905044556 37.325995917556895 35.0 1.0 no 2286 chrIV_839272r 6981 essential YDR189W 883 - ACTTTCAAGTGGAATAGTAA S|301|T S|301|N E|300|Q E|300|K SLY1 Suppressor of Loss of Ypt1 666.0 0 0 0 0 -0.8048709544768474 P22213 0.9669449925422668 0.9709960222244264 0.97645902633667 0.9644089937210084 0.5245597362518309 0.5351320505142212 0.4770763218402863 0.7201609611511229 37.389016517396605 30.0 1.0 no 2287 chrIV_839276 6983 essential YDR189W 884 + TACTATTCCACTTGAAAGTA T|296|S T|296|I SLY1 Suppressor of Loss of Ypt1 666.0 0 0 0 0 0.35121370186006384 P22213 0.9665899872779846 0.9646379947662354 0.44404104351997375 0.037394586950540536 39.57726345904922 30.0 1.0 no 2288 chrIV_839283r 6984 essential YDR189W 894 - CCGTTTTCCTTACTTTCAAG G|305|R G|305|R SLY1 Suppressor of Loss of Ypt1 666.0 0 0 0 0 0.3846873127775592 P22213 0.9477360248565674 0.9477360248565674 47.525474236307275 40.0 1.0 no 2289 chrIV_839400r 6986 essential YDR189W 1011 - TCAACGTTCTCTGCAGCTTC E|344|Q E|344|K V|343|L V|343|I SLY1 Suppressor of Loss of Ypt1 666.0 0 0 0 0 -0.0035331062694967798 P22213 0.9202449917793274 0.9081959724426271 0.9786369800567628 0.9863060116767884 0.03606157377362251 0.028879376128315926 0.5312528014183044 0.9940075278282166 52.18295108024324 50.0 1.0 no 2290 chrIV_839399r 6988 essential YDR189W 1010 - CAACGTTCTCTGCAGCTTCT V|343|L V|343|I SLY1 Suppressor of Loss of Ypt1 666.0 0 0 0 0 -2.5087261968905024 P22213 0.9786369800567628 0.9863060116767884 0.5312528014183044 0.9940075278282166 52.88541756690364 50.0 1.0 yes 2291 chrIV_839454 6991 essential YDR189W 1062 + GCAGAAATTACTAGGAAAAC A|355|G A|355|V SLY1 Suppressor of Loss of Ypt1 666.0 0 0 0 0 -0.4529527791029852 P22213 0.9678980112075806 0.9671239852905272 0.30297985672950745 0.21649841964244845 34.33212513032652 35.0 1.0 no 2292 chrIV_839771 6994 essential YDR189W 1379 + ATCAACGACAGGCTTACCAA S|461|* S|461|L T|462|R T|462|M SLY1 Suppressor of Loss of Ypt1 666.0 0 0 0 0 -0.6367171180163715 P22213 0.9508730173110962 0.9528260231018066 0.9669359922409058 0.09065781533718108 0.5317990183830261 0.10465292632579803 46.223771353203524 45.0 1.0 no 2293 chrIV_840981r 6997 essential YDR190C 992 + TATCGCCCCCGTTGTTGTAT I|332|M silent|ATC>ATT|I|332 A|333|G A|333|V RVB1 RuVB-like 463.0 0 0 0 0 -1.0970632956131494 Q03940 0.9346629977226256 0.8726660013198853 0.8665040135383606 0.3214235305786133 0.01302206702530384 0.054374758154153824 -0.5088000297546387 0.6516000032424927 2.373600006103516 57.836966629174746 50.0 0.0 no 2294 chrIV_841277 7000 essential YDR190C 699 - TTCTTATGCACTTCGCCTTT K|239|N silent|AAG>AAA|K|239 RVB1 RuVB-like 463.0 0 0 0 0 -0.4813410274064684 Q03940 0.9018030166625975 0.0051108868792653075 -0.3334000110626221 51.58926371474047 40.0 0.0 no 2295 chrIV_841323r 7002 essential YDR190C 650 + ATACGCTACTGAATTTGATT Y|218|* silent|TAC>TAT|Y|218 A|219|G A|219|V RVB1 RuVB-like 463.0 0 0 0 0 -1.4328619520828418 Q03940 0.9672009944915771 0.9664270281791688 0.02302928455173969 0.0291127972304821 1.1175999641418457 3.1092000007629395 39.44096946631487 30.0 0.0 no 2296 chrIV_841357 7004 essential YDR190C 619 - GCCAACTCGCTTAACTGCAC G|213|R G|213|S G|213|A G|213|D RVB1 RuVB-like 463.0 0 0 0 0 -1.9462982573529208 Q03940 0.9727219939231871 0.9916149973869324 0.9903749823570251 0.9780880212783812 0.0 0.0 0.0 0.0 51.86106184022998 55.00000000000001 0.0 no 2297 chrIV_841456 7006 essential YDR190C 520 - TCTTAGTGTCTTGGTACCCT R|180|T R|180|K RVB1 RuVB-like 463.0 0 0 0 0 -0.1884826654455201 Q03940 0.955632984638214 0.9748079776763916 0.044740941375494 1.0 55.10245274311177 45.0 0.0 no 2298 chrIV_841490r 7008 essential YDR190C 483 + ACTATCTCACATGTAATTGT T|162|S T|162|I I|163|M silent|ATC>ATT|I|163 RVB1 RuVB-like 463.0 0 0 0 0 1.1383352497580366 Q03940 0.9665899872779846 0.9646379947662354 0.9787610173225404 0.3109928071498871 0.0529501736164093 0.0082505252212286 0.373199999332428 40.85764993106318 30.0 0.0 no 2299 chrIV_841615 7012 essential YDR190C 361 - TCTTCTAAAATTTTCCATTA R|127|T R|127|K R|126|T R|126|K RVB1 RuVB-like 463.0 0 0 0 0 -0.478630711353475 Q03940 0.7878609895706177 0.8167579770088196 0.8403450250625609 0.8711959719657898 0.0050529097206890574 0.6399426460266113 0.003579160664230585 0.013679409399628641 36.795473744147046 20.0 0.0 no 2300 chrIV_841676r 7014 essential YDR190C 297 + GTTCCATTCTGTCCTCTTGT P|101|A P|101|S P|101|R P|101|L RVB1 RuVB-like 463.0 0 0 0 0 -0.15358103950194482 Q03940 0.8326749801635742 0.8368340134620667 0.783411979675293 0.7679579854011536 0.0058366707526147366 0.003811665112152696 0.03173493593931198 0.0028711340855807066 57.25854110926292 45.0 0.0 no 2301 chrIV_848652 7023 high_effect YDR195W 53 + CACTATCCAGCAAATTCGTT T|19|S T|19|I I|20|M silent|ATC>ATT|I|20 REF2 RNA End Formation 533.0 0 0 0 0 -0.2400843025746725 P42073 0.9491789937019348 0.9472420215606691 0.9598389863967896 0.242439404129982 0.5469124317169191 0.015282149426639082 45.573806532951714 40.0 1.0 no 2302 chrIV_849027r 7032 high_effect YDR195W 431 - CCATTTTAGATAATCGATTA M|150|I M|150|I REF2 RNA End Formation 533.0 0 0 0 0 0.1876692305522478 P42073 0.9553959965705872 0.9553959965705872 0.1206268072128296 0.1206268072128296 37.32065076706056 25.0 1.0 no 2303 chrIV_849031 7033 high_effect YDR195W 432 + AATCGATTATCTAAAATGGA R|146|G R|146|* REF2 RNA End Formation 533.0 0 0 0 0 -0.9537576527252912 P42073 0.8994590044021606 0.34933531284332275 33.310528967811706 25.0 1.0 no 2304 chrIV_849570 7046 high_effect YDR195W 971 + GTCAGGATCGTCAACCACAA S|325|* S|325|L REF2 RNA End Formation 533.0 0 0 0 0 -0.6241164573757155 P42073 0.9298099875450134 48.92951378590322 50.0 1.0 no 2305 chrIV_856343r 7048 essential YDR201W 29 - AAACTGTTCCCTCCAACGCA V|16|L V|16|I SPC19 Spindle Pole Component 165.0 0 0 0 0 -0.8243265505691042 Q03954 0.9539830088615416 0.9574310183525084 0.0 0.0 52.14851525157872 50.0 1.0 no 2306 chrIV_856467r 7054 essential YDR201W 153 - GATCTTTCAACATCATATTC R|57|T R|57|K SPC19 Spindle Pole Component 165.0 0 0 0 0 -2.09466031620712 Q03954 0.932735025882721 0.955805003643036 0.1063804104924202 0.5457774400711061 39.05311412213547 30.0 1.0 yes 2307 chrIV_865636 7064 high_effect YDR207C 1867 - CCTTGTCCTTGACTCAAAAG R|629|T R|629|K R|627|S silent|AGG>AGA|R|627 UME6 Unscheduled Meiotic gene Expression 836.0 0 0 0 0 1.168296396074512 P39001 0.979092001914978 0.9988390207290648 0.9618290066719056 0.10807829350233078 0.7809293866157532 0.7393494844436646 45.78033757480768 45.0 0.0 no 2308 chrIV_865636r 7065 high_effect YDR207C 1864 + CCACTTTTGAGTCAAGGACA T|623|S T|623|I silent|CCC>CCG|P|622 silent|CCC>CCT|P|622 UME6 Unscheduled Meiotic gene Expression 836.0 0 1 0 0 -0.5527001929979575 P39001 0.9913139939308168 0.9893620014190674 47.43064673448054 45.0 0.0 no 2309 chrIV_866030r 7070 high_effect YDR207C 1470 + TACATCAATTCTAAATTGGA Y|491|* silent|TAC>TAT|Y|491 I|492|M silent|ATC>ATT|I|492 UME6 Unscheduled Meiotic gene Expression 836.0 0 1 0 0 0.20346903487292908 P39001 0.9225469827651978 0.09966759383678436 34.986838132491414 25.0 0.0 no 2310 chrIV_866140r 7072 high_effect YDR207C 1360 + CTTCGTCAAGACCTTCTACT S|455|W S|455|L S|456|* S|456|L UME6 Unscheduled Meiotic gene Expression 836.0 0 0 0 0 -0.733461346083861 P39001 0.966612994670868 0.9753659963607788 0.9753659963607788 0.1072816401720047 0.5219943523406982 0.3582373857498169 49.011967970972655 45.0 0.0 no 2311 chrIV_866141r 7073 high_effect YDR207C 1359 + ACTTCGTCAAGACCTTCTAC T|454|S T|454|I S|455|W S|455|L UME6 Unscheduled Meiotic gene Expression 836.0 0 0 0 0 0.8901417941457431 P39001 0.9910879731178284 0.9891359806060792 0.966612994670868 0.9753659963607788 0.7671527862548828 0.6206788420677185 0.1072816401720047 0.5219943523406982 47.64304086089577 45.0 0.0 no 2312 chrIV_866129 7075 high_effect YDR207C 1374 - CCGTAAAAAAACCCAGTAGA G|465|R G|465|S UME6 Unscheduled Meiotic gene Expression 836.0 0 0 0 0 0.46118396436899 P39001 0.9727219939231871 0.9916149973869324 0.08672790229320526 0.2422578930854797 40.6378376913126 40.0 0.0 no 2313 chrIV_866318 7081 high_effect YDR207C 1185 - TTCGCATGTCGAGAGTTTGT silent|GCG>GCC|A|401 silent|GCG>GCA|A|401 A|401|P A|401|T UME6 Unscheduled Meiotic gene Expression 836.0 0 0 0 1 -0.7407529113561586 P39001 1.002079963684082 0.9944819808006288 0.21797476708889008 0.6899363398551941 49.67036934938153 45.0 0.0 no 2314 chrIV_866346r 7082 high_effect YDR207C 1154 + CAACAATGCTAGTTCAAACA N|386|K silent|AAC>AAT|N|386 UME6 Unscheduled Meiotic gene Expression 836.0 0 0 0 0 0.6881540453475175 P39001 0.9907550215721129 0.7235935926437378 38.45217760077446 35.0 0.0 no 2315 chrIV_866454r 7083 high_effect YDR207C 1046 + AACAGACCCAAATGTAAAAC T|350|R T|350|I D|351|E silent|GAC>GAT|D|351 UME6 Unscheduled Meiotic gene Expression 836.0 0 1 0 0 -2.024800100942854 P39001 0.9773380160331726 0.9893620014190674 0.9954699873924256 0.07145825773477554 0.28015124797821045 0.2273895889520645 36.343263218996704 35.0 0.0 yes 2316 chrIV_866612r 7091 high_effect YDR207C 888 + TCCTCTAATAACAATGAGAT silent|TCC>TCG|S|297 silent|TCC>TCT|S|297 S|297|C S|297|F UME6 Unscheduled Meiotic gene Expression 836.0 0 0 0 0 -0.4882832581407386 P39001 0.994148015975952 0.974826991558075 0.058921493589878075 0.05324634164571762 37.597573552362924 30.0 0.0 no 2317 chrIV_866690 7092 high_effect YDR207C 813 - TTTCTGCTCAGTATCGACAT R|277|T R|277|K S|276|T S|276|N UME6 Unscheduled Meiotic gene Expression 836.0 0 1 0 0 -0.7572355975071194 P39001 0.9851019978523254 1.0048500299453735 0.9926310181617736 0.9966819882392884 0.3202330470085144 0.7606774568557739 47.65201887595936 40.0 0.0 no 2318 chrIV_866722 7093 high_effect YDR207C 781 - AGTCTTACCGTTGTTCTTGT K|266|N silent|AAG>AAA|K|266 UME6 Unscheduled Meiotic gene Expression 836.0 0 1 0 0 0.6241256356516589 P39001 0.9868599772453308 0.4130285680294037 51.5526412590636 40.0 0.0 no 2319 chrIV_866761 7094 high_effect YDR207C 742 - CGGCAAATCCGATCCTGTGC L|253|F silent|TTG>TTA|L|253 UME6 Unscheduled Meiotic gene Expression 836.0 0 1 0 0 -0.1918257974200966 P39001 1.009179949760437 53.84888882170844 60.0 0.0 no 2320 chrIV_866968 7115 high_effect YDR207C 535 - ATACTGCGGCTGAATAGCAC Q|184|H silent|CAG>CAA|Q|184 silent|CCG>CCC|P|183 silent|CCG>CCA|P|183 UME6 Unscheduled Meiotic gene Expression 836.0 0 0 0 0 -0.21255754175535307 P39001 1.0067000389099119 48.15364726524222 50.0 0.0 no 2321 chrIV_866987r 7116 high_effect YDR207C 513 + GCTACAGACCCACAAATTTC A|172|G A|172|V T|173|R T|173|I UME6 Unscheduled Meiotic gene Expression 836.0 0 0 0 0 0.2905664151483044 P39001 0.9928870201110841 0.992114007472992 0.9782999753952026 0.9903240203857422 46.727629492394044 45.0 0.0 no 2322 chrIV_867000 7117 high_effect YDR207C 503 - GGTCTGTAGCCTGTGCGACA D|174|H D|174|N UME6 Unscheduled Meiotic gene Expression 836.0 0 0 0 0 -1.0866793842841964 P39001 0.9909110069274902 1.0014499425888062 59.225637109625275 60.0 0.0 no 2323 chrIV_867029 7119 high_effect YDR207C 474 - CACAATGACTTAGGATCCGA L|164|F silent|TTG>TTA|L|164 UME6 Unscheduled Meiotic gene Expression 836.0 0 0 0 0 -0.32961039369560685 P39001 1.0041300058364868 44.861977960137146 45.0 0.0 no 2324 chrIV_867179 7125 high_effect YDR207C 324 - CCACTTTGGACTTTCAAACT S|114|T S|114|N G|115|R G|115|S UME6 Unscheduled Meiotic gene Expression 836.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.10705746543982267 P39001 0.9926310181617736 0.9966819882392884 0.9739099740982056 0.9925770163536072 45.05469800601486 40.0 0.0 no 2325 chrIV_867206r 7128 high_effect YDR207C 294 + ACTCCCGTGCATACTCCGTC P|100|A P|100|S T|99|S T|99|I UME6 Unscheduled Meiotic gene Expression 836.0 0 1 0 0 -0.6350190174974278 P39001 1.0064300298690796 0.9986460208892822 0.997323989868164 0.9953709840774536 59.672341204743255 60.0 0.0 no 2326 chrIV_868461r 7140 essential YDR208W 240 - GACTCACCATCTGACAAGCG E|86|D silent|GAG>GAA|E|86 E|86|Q E|86|K MSS4 Multicopy Suppressor of Stt4 mutation 779.0 0 1 0 0 -0.2527384964563103 P38994 0.94931298494339 0.956179976463318 0.9475290179252625 49.548863300485614 55.00000000000001 1.0 no 2327 chrIV_868577 7143 essential YDR208W 353 + TGACAACAGCAATAATAATA D|119|E silent|GAC>GAT|D|119 N|120|K silent|AAC>AAT|N|120 MSS4 Multicopy Suppressor of Stt4 mutation 779.0 0 1 0 0 -0.2595520149830097 P38994 0.9532920122146606 0.9439849853515624 32.48702856698452 25.0 1.0 no 2328 chrIV_868677r 7145 essential YDR208W 456 - TTCTTCGACTCCTTACCTTC K|158|N silent|AAG>AAA|K|158 silent|TCG>TCC|S|157 silent|TCG>TCA|S|157 MSS4 Multicopy Suppressor of Stt4 mutation 779.0 0 0 0 0 -0.7512235431719637 P38994 0.9355990290641784 0.4974644482135773 52.128748188875186 45.0 1.0 no 2329 chrIV_868634 7146 essential YDR208W 410 + ACCAAATAGCACTAGTAACA P|138|R P|138|L P|138|A P|138|S MSS4 Multicopy Suppressor of Stt4 mutation 779.0 0 0 0 0 1.0225921182586812 P38994 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 40.47434743448639 35.0 1.0 no 2330 chrIV_868635r 7147 essential YDR208W 414 - TCCTTGTTACTAGTGCTATT K|144|N silent|AAG>AAA|K|144 E|145|Q E|145|K MSS4 Multicopy Suppressor of Stt4 mutation 779.0 0 0 0 0 0.3786306497844353 P38994 0.9355990290641784 0.956179976463318 0.9475290179252625 48.08594518524393 35.0 1.0 no 2331 chrIV_868711r 7148 essential YDR208W 490 - ACAATTATTCGAGTTTAACG C|170|S C|170|Y MSS4 Multicopy Suppressor of Stt4 mutation 779.0 0 1 0 0 -0.1946717449678124 P38994 0.9421560168266296 0.9290120005607604 0.6661849021911621 1.0 36.232605090805244 30.0 1.0 no 2332 chrIV_868931 7152 essential YDR208W 707 + GCATTCTCAAATTCTACCTA H|237|D H|237|Y S|238|C S|238|F MSS4 Multicopy Suppressor of Stt4 mutation 779.0 0 1 0 0 0.1965473298040108 P38994 0.9473130106925964 0.9489949941635132 0.945252001285553 0.9294660091400146 0.3523114919662476 1.0 0.02279020845890045 0.016511907801032066 44.56563581572505 35.0 1.0 no 2333 chrIV_869162r 7155 essential YDR208W 941 - CAGCATTAGCAGCGTGATTA A|320|P A|320|T MSS4 Multicopy Suppressor of Stt4 mutation 779.0 0 0 0 0 -0.3376802091585984 P38994 0.9573720097541808 0.9523990154266356 0.29892250895500183 0.6044858694076538 48.71580124574223 45.0 1.0 no 2334 chrIV_869204 7156 essential YDR208W 980 + TACTACTACTACCGCTGCTA T|328|S T|328|I T|329|S T|329|I MSS4 Multicopy Suppressor of Stt4 mutation 779.0 0 0 0 0 -0.6762376147953889 P38994 0.9491789937019348 0.9472420215606691 0.9491789937019348 0.9472420215606691 1.0 0.5142982602119446 0.9341769218444824 0.5023802518844604 49.60758144012499 45.0 1.0 no 2335 chrIV_869205 7157 essential YDR208W 981 + ACTACTACTACCGCTGCTAC T|328|S T|328|I T|329|S T|329|I MSS4 Multicopy Suppressor of Stt4 mutation 779.0 0 0 0 0 0.3053138148168421 P38994 0.9491789937019348 0.9472420215606691 0.9491789937019348 0.9472420215606691 1.0 0.5142982602119446 0.9341769218444824 0.5023802518844604 50.60335367995231 50.0 1.0 no 2336 chrIV_869415 7161 essential YDR208W 1191 + GTCGCAGTGTCACGTTGTTC silent|GTC>GTG|V|398 silent|GTC>GTT|V|398 A|399|G A|399|V MSS4 Multicopy Suppressor of Stt4 mutation 779.0 0 0 0 0 -1.7521880195616673 P38994 0.9484469890594482 0.9504740238189696 0.08569634705781938 0.010173547081649305 55.41205546288671 55.00000000000001 1.0 no 2337 chrIV_869481 7162 essential YDR208W 1257 + AAGCTTGCCTTTGATTATCA L|421|V L|421|F MSS4 Multicopy Suppressor of Stt4 mutation 779.0 0 0 0 0 1.14808420616561 P38994 0.9512209892272948 0.9587849974632264 0.1139792799949646 0.22241239249706268 46.53862828449104 35.0 1.0 no 2338 chrIV_869457r 7163 essential YDR208W 1236 - TTCGTAAATCTAAAGTCTGC silent|ACG>ACC|T|418 silent|ACG>ACA|T|418 MSS4 Multicopy Suppressor of Stt4 mutation 779.0 0 0 0 0 0.5367621621133836 P38994 38.999248163754366 35.0 1.0 no 2339 chrIV_869525 7164 essential YDR208W 1301 + TCAGTATGCATTTAAGTTTA Q|435|E Q|435|* MSS4 Multicopy Suppressor of Stt4 mutation 779.0 0 0 0 0 -0.2755507669726142 P38994 0.9590039849281312 0.04311569780111313 39.20370371830876 25.0 1.0 no 2340 chrIV_869549 7165 essential YDR208W 1325 + CTACTGTCCCGAAGTCTTTA Y|443|* silent|TAC>TAT|Y|443 MSS4 Multicopy Suppressor of Stt4 mutation 779.0 0 0 0 0 -0.2323594575663377 P38994 50.19799590919661 45.0 1.0 no 2341 chrIV_869548 7166 essential YDR208W 1324 + ACTACTGTCCCGAAGTCTTT D|442|E silent|GAC>GAT|D|442 Y|443|* silent|TAC>TAT|Y|443 MSS4 Multicopy Suppressor of Stt4 mutation 779.0 0 0 0 0 -0.07377907724520694 P38994 0.9532920122146606 0.0 51.2138059488969 45.0 1.0 no 2342 chrIV_869597r 7167 essential YDR208W 1376 - ACGAAACCAAATAATCAGCA silent|TCG>TCC|S|465 silent|TCG>TCA|S|465 V|464|L V|464|I MSS4 Multicopy Suppressor of Stt4 mutation 779.0 0 0 0 0 -0.2558160367128258 P38994 0.9539830088615416 0.9574310183525084 0.0912051796913147 0.3923940062522888 37.98109337315304 35.0 1.0 no 2343 chrIV_884898r 7177 essential YDR211W 174 - TCTAAGGTGTATTCAATGAG E|65|Q E|65|K GCD6 General Control Derepressed 712.0 0 0 0 0 0.5567714167615423 P32501 0.956179976463318 0.9475290179252625 0.0 0.0 39.00341753012316 35.0 1.0 no 2344 chrIV_885051 7185 essential YDR211W 324 + TCTCCAGAAGCTAGATGTAC P|110|A P|110|S S|109|C S|109|F GCD6 General Control Derepressed 712.0 0 0 0 0 0.42221752307428784 P32501 0.9562489986419678 0.9498909711837769 0.945252001285553 0.9294660091400146 0.6205968856811523 0.29628878831863403 0.017654890194535255 0.011608847416937351 46.68162710536666 45.0 1.0 no 2345 chrIV_885327r 7186 essential YDR211W 603 - TTCTCTCTAGAGCTTGGTAA E|207|D silent|GAG>GAA|E|207 E|207|Q E|207|K GCD6 General Control Derepressed 712.0 0 0 0 0 -0.25077496585642844 P32501 0.94931298494339 0.956179976463318 0.9475290179252625 0.6125364899635315 0.5808584094047546 0.956396758556366 47.51185196455981 40.0 1.0 no 2346 chrIV_885359 7187 essential YDR211W 632 + TCAGATTGACCCAGAATTGT Q|212|E Q|212|* GCD6 General Control Derepressed 712.0 0 0 0 0 0.3369059425075025 P32501 0.9590039849281312 1.0 46.1975928430761 40.0 1.0 no 2347 chrIV_885368r 7188 essential YDR211W 644 - CGACATTATCCAACAATTCT V|221|L V|221|I GCD6 General Control Derepressed 712.0 0 0 0 0 0.2035906427249464 P32501 0.9539830088615416 0.9574310183525084 0.9284371733665466 0.5886073708534241 41.32412347653286 35.0 1.0 no 2348 chrIV_885413r 7189 essential YDR211W 689 - TGTCAATTCTACAATCGATG D|236|H D|236|N GCD6 General Control Derepressed 712.0 0 0 0 0 0.1000798994891074 P32501 0.9486550092697144 0.956179976463318 0.0 0.0 38.885154314528734 35.0 1.0 no 2349 chrIV_885512 7190 essential YDR211W 785 + TGTCATTTCAAGCGATATAT silent|GTC>GTG|V|263 silent|GTC>GTT|V|263 GCD6 General Control Derepressed 712.0 0 0 0 0 0.5858136944940393 P32501 40.396538164982424 30.0 1.0 no 2350 chrIV_885550r 7192 essential YDR211W 826 - AGCATATTCGTCCGTCAAAT A|282|P A|282|T GCD6 General Control Derepressed 712.0 0 0 0 0 -0.576385690531802 P32501 0.9573720097541808 0.9523990154266356 0.0492144450545311 0.05350537970662117 46.4213648365718 40.0 1.0 no 2351 chrIV_885603 7194 essential YDR211W 876 + ACCATTTCTCAAGACTTTTT silent|ACC>ACG|T|293 silent|ACC>ACT|T|293 T|293|S T|293|I GCD6 General Control Derepressed 712.0 0 0 0 0 0.4216809579558773 P32501 0.9491789937019348 0.9472420215606691 0.21549536287784574 0.009690361097455023 43.487115774245694 30.0 1.0 no 2352 chrIV_885610 7196 essential YDR211W 883 + CTCAAGACTTTTTAGGTAGA Q|296|E Q|296|* GCD6 General Control Derepressed 712.0 0 0 0 0 0.7934621111443994 P32501 0.9590039849281312 0.055030319839715965 41.38147885531646 35.0 1.0 no 2353 chrIV_885644 7197 essential YDR211W 917 + GGTCTTAGACTCTAACATAC silent|GTC>GTG|V|307 silent|GTC>GTT|V|307 GCD6 General Control Derepressed 712.0 0 0 0 0 0.026777585106164403 P32501 42.461559825095776 40.0 1.0 no 2354 chrIV_885824r 7201 essential YDR211W 1100 - TTCTAATATTTTCACCGATT R|373|T R|373|K GCD6 General Control Derepressed 712.0 0 0 0 0 -0.4812589812190355 P32501 0.932735025882721 0.955805003643036 0.5966641902923584 0.975085973739624 39.89235722571732 25.0 1.0 no 2355 chrIV_885916r 7203 essential YDR211W 1192 - ACTCCCTAACGTGGCATTAG silent|GGG>GGC|G|403 silent|GGG>GGA|G|403 S|404|T S|404|N GCD6 General Control Derepressed 712.0 0 0 1 Series([], Name: modification, dtype: object) 0 -0.3210218185914413 P32501 0.9512869715690612 0.9536849856376648 0.4830023944377899 0.4688709974288941 50.9526131612401 50.0 1.0 no 2356 chrIV_887256 7208 essential YDR212W 24 + CGCTCAGATACCCTTTTCCT silent|CGC>CGG|R|9 silent|CGC>CGT|R|9 S|10|* S|10|L TCP1 Tailless Complex Polypeptide 559.0 0 0 0 1 -1.904405046402836 P12612 0.9487630128860474 0.2181610316038132 0.03579999506473541 55.98032479383539 50.0 1.0 no 2357 chrIV_887368r 7215 essential YDR212W 139 - AAGCATTTTGTCCAGTCCAA M|52|I M|52|I TCP1 Tailless Complex Polypeptide 559.0 0 0 0 0 0.4034944595110021 P12612 0.9457209706306458 0.9457209706306458 0.050679061561822884 0.050679061561822884 0.2906000018119812 0.2906000018119812 49.38946877806313 40.0 1.0 no 2358 chrIV_887431r 7216 essential YDR212W 202 - ATCTAACAAAGACAAAATAG D|74|H D|74|N L|72|F silent|TTG>TTA|L|72 TCP1 Tailless Complex Polypeptide 559.0 0 0 0 0 -1.642461184958907 P12612 0.9573519825935364 0.9906269907951356 0.95687597990036 0.09263961762189864 0.3353027403354645 0.10321646928787233 0.17100000381469727 28.645412260856858 25.0 1.0 no 2359 chrIV_887592 7220 essential YDR212W 360 + CATCCAACTACCATCATAAC P|122|A P|122|S P|122|R P|122|L TCP1 Tailless Complex Polypeptide 559.0 0 0 0 0 -0.512328455931452 P12612 0.9886239767074584 0.9653319716453552 0.844353973865509 0.8574029803276062 0.13871897757053375 0.020745353773236275 0.0033496455289423466 0.008557253517210484 2.7827999591827397 4.575799942016602 7.335599899291992 3.026400089263916 43.2262828557067 40.0 1.0 no 2360 chrIV_887664 7221 essential YDR212W 432 + TCCACAAGTGTTGACACTTT silent|TCC>TCG|S|145 silent|TCC>TCT|S|145 S|145|C S|145|F TCP1 Tailless Complex Polypeptide 559.0 0 0 0 0 -0.4748110813552927 P12612 0.9581969976425172 0.8542410135269165 0.033812042325735085 0.03208429366350174 46.75129077366347 40.0 1.0 no 2361 chrIV_887725r 7225 essential YDR212W 496 - GTCAGCACCAATGATCTTAG D|172|H D|172|N A|171|P A|171|T TCP1 Tailless Complex Polypeptide 559.0 0 0 0 0 -3.54737607826096 P12612 0.9676650166511536 1.0163799524307249 1.0119999647140503 1.009660005569458 0.027880992740392685 0.21640273928642276 0.28969937562942505 0.5649502277374268 2.1772000789642334 -0.6796000003814697 46.97569102505617 45.0 1.0 yes 2362 chrIV_887827r 7226 essential YDR212W 598 - CAACACATTGACAGCCTTTA silent|GTG>GTC|V|205 silent|GTG>GTA|V|205 V|205|L V|205|M TCP1 Tailless Complex Polypeptide 559.0 0 0 0 0 0.4027427527324589 P12612 1.0098700523376465 0.8680210113525391 0.05094866082072258 0.003099597990512848 45.08049262103635 40.0 1.0 no 2363 chrIV_887864 7229 essential YDR212W 632 + ATCTGCCACTGAATCACTGT S|212|C S|212|F A|213|G A|213|V TCP1 Tailless Complex Polypeptide 559.0 0 1 0 0 0.2552563849951752 P12612 0.9289829730987548 0.9137160181999208 0.9808459877967834 1.0130599737167358 0.002106020925566554 0.0012587818782776596 0.07867958396673203 1.0 0.6913999915122986 0.30379998683929443 49.88739619835542 45.0 1.0 no 2364 chrIV_887944r 7234 essential YDR212W 715 - TGCGATTTTCACATTGCCAC A|245|P A|245|T TCP1 Tailless Complex Polypeptide 559.0 0 0 0 0 -0.6699189091752991 P12612 0.8560199737548828 0.9476320147514344 0.07859121263027191 0.28402990102767944 49.48291767354988 45.0 1.0 no 2365 chrIV_888322r 7242 essential YDR212W 1093 - ACACTCATCATCAGAAAATT E|370|D silent|GAG>GAA|E|370 C|371|S C|371|Y TCP1 Tailless Complex Polypeptide 559.0 0 0 0 0 -0.5978406319995633 P12612 1.0109599828720093 0.9523940086364746 0.9897220134735109 0.28357309103012085 0.03127993643283844 0.13021855056285858 1.1749999523162842 -0.5293999910354614 37.355597569284896 30.0 1.0 no 2366 chrIV_888375 7243 essential YDR212W 1143 + TCTTCTTCGATCATTTTAAG S|382|C S|382|F S|383|C S|383|F TCP1 Tailless Complex Polypeptide 559.0 0 0 0 0 0.06699409253544072 P12612 0.9605950117111206 0.8458179831504822 0.9645720124244691 0.8530610203742981 0.10132388025522232 0.06727829575538635 0.0686635747551918 0.14281374216079712 1.6998000144958496 18.05699920654297 -0.8262000083923341 -0.9297999739646912 39.724325925461706 30.0 1.0 no 2367 chrIV_914611 7249 essential YDR224C 82 - GCTTCTCTTCTTACCATCAG S|34|T S|34|N R|33|T R|33|K 0 1 0 0 -2.803083152366081 P02293 0.9512869715690612 0.9536849856376648 0.932735025882721 0.955805003643036 0.1289142221212387 0.12929730117321014 0.052029721438884735 0.4577348828315735 2.3644399642944336 -0.10292000323534012 0.2736999988555908 -0.07373999804258348 1.7095671892166138 0.935616672039032 51.862760378448 45.0 0.0 yes 2368 chrIV_916491 7253 high_effect YDR226W 5 + TAGCTCAGAATCCATTAGAA S|3|R silent|AGC>AGT|S|3 S|4|* S|4|L ADK1 ADenylate Kinase 222.0 0 1 0 0 -0.8331472140571186 P07170 0.9515600204467772 0.9003270268440247 0.5106635093688965 0.28934985399246216 41.8539719175306 35.0 1.0 no 2369 chrIV_916648 7261 high_effect YDR226W 162 + GCAAAGAAAATTATGGACCA A|55|G A|55|V ADK1 ADenylate Kinase 222.0 0 1 0 0 0.8490806235834408 P07170 0.607928991317749 0.8542550206184387 0.007502454798668624 0.4723565876483917 2.13112211227417 -1.7498500347137451 2.183510065078736 -1.5059679746627808 37.69336526958665 35.0 1.0 no 2370 chrIV_916835r 7268 high_effect YDR226W 352 - ATCATCAACCTTCAATTCGA D|124|H D|124|N D|123|H D|123|N ADK1 ADenylate Kinase 222.0 0 0 0 0 0.9704969707961036 P07170 0.6272090077400208 0.6660760045051575 0.8176389932632446 0.9336770176887512 0.002344486536458135 0.00661015510559082 0.06238195300102234 0.3632814288139343 0.32282400131225586 -0.4129959940910339 0.3287839889526367 0.37553998827934265 43.187112653602235 35.0 1.0 no 2371 chrIV_916880r 7269 high_effect YDR226W 397 - GGCTGGGTGAATTAATCTAC A|139|P A|139|T ADK1 ADenylate Kinase 222.0 0 1 0 0 0.4430938031771103 P07170 0.9715179800987244 0.937720000743866 0.39712193608284 0.07930663228034973 1.626505970954895 1.0803320407867432 0.9116960167884828 0.3755519986152649 44.96601565861886 45.0 1.0 no 2372 chrIV_916933r 7272 high_effect YDR226W 450 - TCCTTCATGTCTTCCTTTGG K|156|N silent|AAG>AAA|K|156 D|157|H D|157|N ADK1 ADenylate Kinase 222.0 1 Series([], Name: modification, dtype: object) 0 0 0 -3.0162381885798943 P07170 0.8184459805488586 0.6681810021400452 0.7223970293998718 0.052447624504566186 0.0 0.0 1.4515719413757324 5.6052818298339835 1.9891279935836792 54.169086976466815 45.0 1.0 yes 2373 chrIV_916936r 7273 high_effect YDR226W 453 - TCATCCTTCATGTCTTCCTT D|158|H D|158|N D|157|H D|157|N ADK1 ADenylate Kinase 222.0 0 1 0 0 -0.4739045566827783 P07170 0.7767009735107422 0.9016770124435424 0.6681810021400452 0.7223970293998718 0.0 0.0 0.0 0.0 0.3468819856643677 0.30303800106048584 5.6052818298339835 1.9891279935836792 53.88812065788903 40.0 1.0 no 2374 chrIV_922422r 7276 essential YDR228C 1362 + TCACAAAACACAGCAAATAC Q|456|E Q|456|* S|455|* S|455|L PCF11 Protein 1 of Cleavage and polyadenylation Factor I 626.0 0 0 0 0 0.9708815503641088 P39081 0.9590039849281312 0.9298099875450134 1.0 0.2819763422012329 -0.24768400192260745 -0.02401399984955788 35.21596523036635 35.0 0.0 no 2375 chrIV_922385r 7277 essential YDR228C 1399 + ACTTAAATACAACTACCACA N|467|K silent|AAC>AAT|N|467 PCF11 Protein 1 of Cleavage and polyadenylation Factor I 626.0 0 1 0 0 1.1900020905392124 P39081 0.9439849853515624 37.58794146369695 30.0 0.0 no 2376 chrIV_922533 7281 essential YDR228C 1254 - CCACACACGCTACATTTATT C|424|S C|424|Y G|425|R G|425|S PCF11 Protein 1 of Cleavage and polyadenylation Factor I 626.0 0 0 0 0 -1.0269933483517288 P39081 0.9421560168266296 0.9290120005607604 0.941340982913971 0.951104998588562 0.0 0.0 0.008707096800208092 0.054703310132026665 46.366205348566275 40.0 0.0 no 2377 chrIV_922832r 7285 essential YDR228C 952 + ATGCATCTCTTAAGGCTGAA A|319|G A|319|V S|320|C S|320|F PCF11 Protein 1 of Cleavage and polyadenylation Factor I 626.0 0 0 0 0 0.3380650516085643 P39081 0.9484469890594482 0.9504740238189696 0.945252001285553 0.9294660091400146 0.41457369923591614 0.26854345202445984 0.04560992494225502 0.042807910591363914 45.587148625863286 40.0 0.0 no 2378 chrIV_922840r 7286 essential YDR228C 944 + TAACCTCTATGCATCTCTTA N|316|K silent|AAC>AAT|N|316 L|317|V L|317|F PCF11 Protein 1 of Cleavage and polyadenylation Factor I 626.0 0 1 0 0 0.33228136151246146 P39081 0.9439849853515624 0.9512209892272948 0.9587849974632264 0.5371044278144836 0.33969151973724365 0.032910522073507316 45.80730727176035 35.0 0.0 no 2379 chrIV_923032r 7289 essential YDR228C 752 + GCAGCAGTATCACGAAACTA Q|252|E Q|252|* Q|253|E Q|253|* PCF11 Protein 1 of Cleavage and polyadenylation Factor I 626.0 0 0 0 0 -0.7172208394003502 P39081 0.9590039849281312 0.9590039849281312 1.0 0.5297770500183105 45.08090024499978 45.0 0.0 no 2380 chrIV_923319 7293 essential YDR228C 468 - TCAATGTCTCTTAATAGGAG D|163|H D|163|N PCF11 Protein 1 of Cleavage and polyadenylation Factor I 626.0 0 0 0 0 0.6050950327033682 P39081 0.9486550092697144 0.956179976463318 0.0 0.0 39.28320817523394 35.0 0.0 no 2381 chrIV_923317 7294 essential YDR228C 470 - TATCAATGTCTCTTAATAGG D|163|H D|163|N PCF11 Protein 1 of Cleavage and polyadenylation Factor I 626.0 0 0 0 0 -3.174646551774332 P39081 0.9486550092697144 0.956179976463318 0.0 0.0 37.45006191362404 30.0 0.0 yes 2382 chrIV_923362 7296 essential YDR228C 425 - TTGCTTGCAGGTTTTTCTGG A|148|P A|148|T PCF11 Protein 1 of Cleavage and polyadenylation Factor I 626.0 0 0 0 0 0.5067725705302275 P39081 0.9573720097541808 0.9523990154266356 0.3193366229534149 0.23401130735874176 51.92090866181224 45.0 0.0 no 2383 chrIV_923433r 7299 essential YDR228C 351 + ACCGGCCTGCCTCTGTTTGA silent|ACC>ACG|T|118 silent|ACC>ACT|T|118 T|118|S T|118|I PCF11 Protein 1 of Cleavage and polyadenylation Factor I 626.0 0 0 0 0 0.03156122881246913 P39081 0.9491789937019348 0.9472420215606691 1.0 0.044696036726236336 -0.3555999994277954 -0.3444800078868866 62.27918285375199 60.0 0.0 no 2384 chrIV_923471r 7300 essential YDR228C 313 + TCATCAATATGTTTAAGCTT silent|CTC>CTG|L|105 silent|CTC>CTT|L|105 I|106|M silent|ATC>ATT|I|106 PCF11 Protein 1 of Cleavage and polyadenylation Factor I 626.0 0 0 0 0 -0.1062020748724196 P39081 0.9598389863967896 0.0 -0.4934999942779541 38.38478551462527 25.0 0.0 no 2385 chrIV_923518r 7301 essential YDR228C 266 + GTACAAAAGAACATACTTAT Y|90|* silent|TAC>TAT|Y|90 PCF11 Protein 1 of Cleavage and polyadenylation Factor I 626.0 0 0 0 0 -6.702623166174632 P39081 32.214673069129056 25.0 0.0 yes 2386 chrIV_923579 7304 essential YDR228C 208 - GCTGCCAACATTCTTACAAA S|76|T S|76|N G|75|A G|75|D PCF11 Protein 1 of Cleavage and polyadenylation Factor I 626.0 0 0 0 0 0.4615045248606633 P39081 0.9512869715690612 0.9536849856376648 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 0.11959999799728395 -0.4078600108623505 2.884740114212036 2.7530200481414795 45.179978838762 40.0 0.0 no 2387 chrIV_927492 7311 essential YDR232W 40 + CCGCTGTTTCCACACTGAAT A|15|G A|15|V silent|GCC>GCG|A|14 silent|GCC>GCT|A|14 HEM1 HEMe biosynthesis 548.0 0 0 0 0 -0.3064492856622313 P09950 0.9916989803314208 0.9909250140190125 52.170668954919904 50.0 1.0 no 2388 chrIV_927527 7314 essential YDR232W 75 + GCCGCACCACATGCGAAAAA silent|GCC>GCG|A|26 silent|GCC>GCT|A|26 A|26|G A|26|V HEM1 HEMe biosynthesis 548.0 0 0 0 1 -3.36560930109815 P09950 0.9916989803314208 0.9909250140190125 0.2860460579395294 0.05746414512395859 49.27141191489675 55.00000000000001 1.0 yes 2389 chrIV_927631 7320 essential YDR232W 179 + TGCTGCCAACCATTCCACCC A|61|G A|61|V A|62|G A|62|V HEM1 HEMe biosynthesis 548.0 0 0 0 0 -0.016320211954879368 P09950 0.9979339838027954 0.9971609711647034 0.9979339838027954 0.9971609711647034 0.4115768373012543 0.2842578291893005 0.4112191200256348 0.3603100180625916 60.661437840922424 60.0 1.0 no 2390 chrIV_927637 7322 essential YDR232W 185 + CAACCATTCCACCCAGGAGT N|63|K silent|AAC>AAT|N|63 H|64|D H|64|Y HEM1 HEMe biosynthesis 548.0 0 0 0 0 0.37254554644646826 P09950 0.9177160263061525 0.9248980283737184 0.9250500202178956 0.9620320200920104 0.6156116724014282 0.07622764259576797 56.03623838577198 55.00000000000001 1.0 no 2391 chrIV_927727 7325 essential YDR232W 275 + TTTCAACAATATCAACCGAT F|93|L silent|TTC>TTT|F|93 N|94|K silent|AAC>AAT|N|94 HEM1 HEMe biosynthesis 548.0 0 0 0 0 0.08939340126441013 P09950 0.982241988182068 0.9035819768905641 0.054363470524549484 0.8878093957901001 38.39812111203491 30.0 1.0 no 2392 chrIV_927775r 7330 essential YDR232W 326 - TGACCTTGTCCGCCTCTCTC V|115|L V|115|I K|114|N silent|AAG>AAA|K|114 HEM1 HEMe biosynthesis 548.0 0 0 0 0 1.1234340590325873 P09950 0.9786369800567628 0.9863060116767884 0.95727801322937 0.012297237291932106 0.2582898437976837 0.07071703672409058 61.580768292865 60.0 1.0 no 2393 chrIV_927823 7331 essential YDR232W 371 + AGCACTTTCCAAGCACCCTG A|125|G A|125|V L|126|V L|126|F HEM1 HEMe biosynthesis 548.0 0 0 0 0 -0.4217712778739017 P09950 0.9747909903526306 0.9740179777145386 0.9254159927368164 0.9341800212860109 1.0 0.007297352887690067 0.006207451689988375 0.005819575395435096 56.24764582220456 55.00000000000001 1.0 no 2394 chrIV_927839r 7334 essential YDR232W 390 - TGCATGGCGTCCAATACCTC M|136|I M|136|I HEM1 HEMe biosynthesis 548.0 0 0 0 0 -3.5215328729023265 P09950 0.9849619865417479 0.9849619865417479 0.208366259932518 0.208366259932518 54.709781278908736 55.00000000000001 1.0 yes 2395 chrIV_927891r 7337 essential YDR232W 442 - AGCAATGTTTCTTGTACCAC A|154|P A|154|T HEM1 HEMe biosynthesis 548.0 0 0 0 0 0.048707843007866784 P09950 0.9863749742507936 0.9780830144882202 0.025875004008412358 0.018868297338485718 46.920035328750544 40.0 1.0 no 2396 chrIV_927919 7338 essential YDR232W 467 + TAACATCCCCACTTTGAATC N|157|K silent|AAC>AAT|N|157 I|158|M silent|ATC>ATT|I|158 HEM1 HEMe biosynthesis 548.0 0 0 0 0 0.7782030614181675 P09950 0.96908301115036 0.988048017024994 0.04462837055325508 0.1445683240890503 46.08227347527816 40.0 1.0 no 2397 chrIV_927762r 7343 essential YDR232W 313 - CTCTCTCTGGCGATGAGCTA E|111|Q E|111|K R|110|T R|110|K HEM1 HEMe biosynthesis 548.0 0 0 0 0 0.39340260132254257 P09950 0.9857460260391236 0.9736970067024232 0.955632984638214 0.9748079776763916 0.5114326477050781 0.7993395924568176 0.5941950678825378 0.8607555031776428 54.514286234321105 55.00000000000001 1.0 no 2398 chrIV_928023r 7344 essential YDR232W 574 - CTTCATCTTTTGACCCAGTA M|197|I M|197|I K|196|N silent|AAG>AAA|K|196 HEM1 HEMe biosynthesis 548.0 0 0 0 0 0.2067912595935261 P09950 0.9756749868392944 0.9756749868392944 0.9665650129318236 0.2663155496120453 0.2663155496120453 0.2971971929073334 50.036228169792935 40.0 1.0 no 2399 chrIV_928224r 7351 essential YDR232W 775 - TTCTATGTCGGCCACTGAAC E|265|Q E|265|K HEM1 HEMe biosynthesis 548.0 0 0 0 0 -1.0252807562942563 P09950 0.97645902633667 0.9644089937210084 0.21076728403568268 0.3860524892807007 49.96257414419586 50.0 1.0 no 2400 chrIV_927953 7356 essential YDR232W 501 + GCCACTTTACACAAGAAGGA silent|GCC>GCG|A|168 silent|GCC>GCT|A|168 A|168|G A|168|V HEM1 HEMe biosynthesis 548.0 0 0 0 0 -1.3722541576326346 P09950 0.9919250011444092 0.991150975227356 0.01055228989571333 0.003204291220754385 45.635992850115315 45.0 1.0 no 2401 chrIV_928395r 7364 essential YDR232W 946 - CTTCGCGCCGCCCTTGTCAT silent|GCG>GCC|A|321 silent|GCG>GCA|A|321 A|321|P A|321|T HEM1 HEMe biosynthesis 548.0 0 0 0 0 0.055514544755123664 P09950 0.9863749742507936 0.9780830144882202 0.07679358124732971 0.17118875682353973 63.52699697163632 65.0 1.0 no 2402 chrIV_928494r 7368 essential YDR232W 1045 - CCAATCGATCAATTTCCTAG W|355|S W|355|* D|354|H D|354|N HEM1 HEMe biosynthesis 548.0 0 1 0 0 -1.4927820207118287 P09950 0.9205849766731262 0.9959579706192015 1.006500005722046 0.06841564178466797 0.0 0.0 43.78218919002211 40.0 1.0 no 2403 chrIV_928666r 7376 essential YDR232W 1217 - TAACTGGAATGCCCAACTCA V|412|L V|412|I HEM1 HEMe biosynthesis 548.0 0 0 0 0 0.2550640829042014 P09950 0.9786369800567628 0.9863060116767884 0.12209424376487732 0.018388250842690468 46.955038138485115 45.0 1.0 no 2404 chrIV_933572r 7379 essential YDR235W 71 - CCCAATATGCCAAACTTTTA W|30|S W|30|* W|30|C W|30|* PRP42 Pre-mRNA Processing 544.0 0 0 0 0 -0.2895450492846895 Q03776 0.0 0.0 44.416155352473936 35.0 1.0 no 2405 chrIV_933953r 7386 essential YDR235W 452 - ATCTTGAGCTAATTTGTTCC R|157|T R|157|K PRP42 Pre-mRNA Processing 544.0 0 0 0 0 0.3033363582964621 Q03776 0.037717968225479126 0.18718264997005465 45.0942191453833 35.0 1.0 no 2406 chrIV_934173r 7389 essential YDR235W 672 - TTCTTTGCATCCTGCAGGTA K|230|N silent|AAG>AAA|K|230 PRP42 Pre-mRNA Processing 544.0 0 0 0 0 -1.1710791908890958 Q03776 0.0714363157749176 54.3933414193745 45.0 1.0 no 2407 chrIV_934178r 7390 essential YDR235W 677 - ACTTTTTCTTTGCATCCTGC K|232|N silent|AAG>AAA|K|232 PRP42 Pre-mRNA Processing 544.0 0 0 0 0 1.7651986526467658 Q03776 0.4940470159053802 51.46830570869236 40.0 1.0 no 2408 chrIV_934468 7393 essential YDR235W 964 + ATTCAAAAAATGACCTTTTG S|323|* S|323|L PRP42 Pre-mRNA Processing 544.0 0 0 0 0 0.7027558076985614 Q03776 0.3469641506671905 33.62597561609516 25.0 1.0 no 2409 chrIV_934469 7394 essential YDR235W 965 + TTCAAAAAATGACCTTTTGG S|323|* S|323|L PRP42 Pre-mRNA Processing 544.0 0 0 0 0 -0.044292391436991485 Q03776 0.3469641506671905 35.75074956705174 30.0 1.0 no 2410 chrIV_934490 7395 essential YDR235W 986 + GGCAAAAAACGTTCTATTAA A|330|G A|330|V PRP42 Pre-mRNA Processing 544.0 0 0 0 0 0.119531934981097 Q03776 0.0 0.0 35.18947112489832 30.0 1.0 no 2411 chrIV_934621r 7397 essential YDR235W 1120 - TTCAACATTGTCGGAATATG E|380|Q E|380|K V|379|L V|379|I PRP42 Pre-mRNA Processing 544.0 0 0 0 0 -0.7565839270211727 Q03776 0.3598333299160004 0.3622766435146332 0.8289781808853149 0.6831978559494019 38.833838947675424 35.0 1.0 no 2412 chrIV_934723 7399 essential YDR235W 1219 + ATTCTGATTCACAATCAAAC S|408|C S|408|F PRP42 Pre-mRNA Processing 544.0 0 0 0 0 0.273181326518012 Q03776 0.03472939133644104 0.03407721221446991 36.276211488213335 30.0 1.0 no 2413 chrIV_935622r 7404 essential YDR236C 248 + TATCAACGATTTGGATTTAG I|84|M silent|ATC>ATT|I|84 N|85|K silent|AAC>AAT|N|85 FMN1 FMN biosynthesis 218.0 0 0 0 0 0.5426523488312431 Q03778 0.9598389863967896 0.9439849853515624 0.2751384675502777 0.7955982685089111 -0.019999999552965164 36.78103825862644 30.0 0.0 no 2414 chrIV_935630 7405 essential YDR236C 243 - TCCAAATCGTTGATACCTTT L|87|F silent|TTG>TTA|L|87 D|88|H D|88|N FMN1 FMN biosynthesis 218.0 0 0 0 0 -0.5360980451897658 Q03778 0.9587849974632264 0.9486550092697144 0.956179976463318 0.25631657242774963 0.11688972264528275 0.5042904615402222 0.8226000070571899 44.593956666098784 35.0 0.0 no 2415 chrIV_935645r 7406 essential YDR236C 225 + CCTATAAATCAGTTACCTAA P|76|R P|76|L FMN1 FMN biosynthesis 218.0 0 1 0 0 0.8815733515168388 Q03778 0.9432820081710817 0.9430609941482544 0.01861093565821648 0.009390446357429028 39.64877613637185 30.0 0.0 no 2416 chrIV_935726 7412 essential YDR236C 147 - TCACAATAGTCAGTAACAAG C|55|S C|55|Y D|56|H D|56|N FMN1 FMN biosynthesis 218.0 0 0 0 0 1.0274266423810254 Q03778 0.9421560168266296 0.9290120005607604 0.9486550092697144 0.956179976463318 0.7241314649581909 0.7394574880599976 0.11616665124893187 0.4978024959564209 -0.8623999953269958 15.272199630737305 36.88652210127583 35.0 0.0 no 2417 chrIV_938889 7423 essential YDR238C 1908 - ACTTCTTCCTTCTTTTCCTC V|643|L V|643|I E|642|Q E|642|K SEC26 SECretory 973.0 0 0 0 0 -0.11455185847738153 P41810 0.9539830088615416 0.9574310183525084 0.956179976463318 0.9475290179252625 0.4760505855083466 0.2894074022769928 0.5645493268966675 0.8748026490211487 53.76978055839192 40.0 0.0 no 2418 chrIV_939115r 7426 essential YDR238C 1679 + TTTCTACACAGCTGCCATTC F|561|L silent|TTC>TTT|F|561 Y|562|* silent|TAC>TAT|Y|562 SEC26 SECretory 973.0 0 0 0 0 0.1294652014217092 P41810 0.9387490153312684 0.013829024508595468 51.370560619307525 45.0 0.0 no 2419 chrIV_939141r 7427 essential YDR238C 1653 + ATTCGCCGGTTTGTTTTAAG R|553|G R|553|C silent|CGC>CGG|R|553 silent|CGC>CGT|R|553 SEC26 SECretory 973.0 0 0 0 0 0.3950077587585812 P41810 0.8994590044021606 0.8926740288734436 0.00407694885507226 0.0005479778628796339 47.06760873779979 40.0 0.0 no 2420 chrIV_939136 7428 essential YDR238C 1661 - AATCACCACTTAAAACAAAC D|560|H D|560|N G|559|A G|559|D SEC26 SECretory 973.0 0 0 0 0 0.4989872402864226 P41810 0.9486550092697144 0.956179976463318 0.9499930143356324 0.9446240067481996 0.06619257479906082 0.01937313750386238 0.03643589839339256 0.009466297924518585 33.86064246491725 30.0 0.0 no 2421 chrIV_939155r 7429 essential YDR238C 1639 + ATTCTAGACCTCCAATTCGC S|548|C S|548|F SEC26 SECretory 973.0 0 0 0 0 -0.36434145644081656 P41810 0.945252001285553 0.9294660091400146 0.05120093747973442 0.0478711910545826 49.737744104851906 45.0 0.0 no 2422 chrIV_939170 7430 essential YDR238C 1627 - TCTAGAATCACGTTCTTCAT R|549|T R|549|K SEC26 SECretory 973.0 0 0 0 0 -3.3586214081394057 P41810 0.932735025882721 0.955805003643036 0.2416859418153763 1.0 43.29757558860075 35.0 0.0 yes 2423 chrIV_939215 7431 essential YDR238C 1582 - CACATCGAAAGCGCTTTCAG V|534|L V|534|M D|533|H D|533|N SEC26 SECretory 973.0 0 0 0 0 0.8699598306784733 P41810 0.9539830088615416 0.9587630033493042 0.9486550092697144 0.956179976463318 0.4912451207637787 0.15806853771209714 0.023889385163784027 0.13281692564487454 45.86457931158702 50.0 0.0 no 2424 chrIV_939328 7436 essential YDR238C 1469 - ACTTTTTGATTTCTGATTGA K|496|N silent|AAG>AAA|K|496 SEC26 SECretory 973.0 0 0 0 0 1.3634764385593052 P41810 0.9355990290641784 0.4591140151023865 39.55061236885484 25.0 0.0 no 2425 chrIV_939585r 7444 essential YDR238C 1209 + TCGCTATTATTAGATTTCAT L|405|V silent|CTA>TTA|L|405 S|404|W S|404|L SEC26 SECretory 973.0 0 0 0 0 0.1105541054959367 P41810 0.9512209892272948 0.9288619756698608 0.9298099875450134 1.0 0.07449332624673842 0.31492429971694946 39.759989626689155 25.0 0.0 no 2426 chrIV_939743 7450 essential YDR238C 1054 - AACAACATCTTCAGCATTTC V|358|L V|358|I V|357|L V|357|I SEC26 SECretory 973.0 0 0 0 0 1.5666444552314158 P41810 0.9539830088615416 0.9574310183525084 0.9539830088615416 0.9574310183525084 0.097980834543705 0.31215527653694153 0.17440922558307648 0.13204088807106018 41.562876619992146 35.0 0.0 no 2427 chrIV_939826 7451 essential YDR238C 971 - TCAAGACTCTCAAAATATCC L|330|F silent|TTG>TTA|L|330 V|329|L V|329|I SEC26 SECretory 973.0 0 0 0 0 0.8078059945348736 P41810 0.9587849974632264 0.9539830088615416 0.9574310183525084 0.010181121528148651 0.047309279441833496 0.2018187791109085 38.6064349982052 35.0 0.0 no 2428 chrIV_939964r 7458 essential YDR238C 830 + TCCAAATGTCTTGGTTCCTG P|278|R P|278|L P|278|A P|278|S SEC26 SECretory 973.0 0 0 0 0 -0.38791621175405855 P41810 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.013820473104715349 0.009196690283715723 0.14922049641609192 0.026398118585348133 49.73289627513622 45.0 0.0 no 2429 chrIV_940060 7461 essential YDR238C 737 - CCATCAATAATTCGATATAT M|252|I M|252|I L|251|F silent|TTG>TTA|L|251 SEC26 SECretory 973.0 0 0 0 0 0.09957500878505887 P41810 0.9553959965705872 0.9553959965705872 0.9587849974632264 0.2877205610275269 0.2877205610275269 0.015275730751454832 36.371204242708416 25.0 0.0 no 2430 chrIV_940060r 7462 essential YDR238C 734 + CCAATATATCGAATTATTGA Q|246|E Q|246|* SEC26 SECretory 973.0 0 0 0 0 0.265828014452878 P41810 0.9590039849281312 0.021531738340854645 35.694609096444424 25.0 0.0 no 2431 chrIV_940061 7463 essential YDR238C 736 - CATCAATAATTCGATATATT L|251|F silent|TTG>TTA|L|251 SEC26 SECretory 973.0 0 0 0 0 0.3218001769037371 P41810 0.9587849974632264 0.015275730751454832 32.87235848526069 20.0 0.0 no 2432 chrIV_940318r 7466 essential YDR238C 476 + AGCAGTTTTCTCCATTTTCA A|160|G A|160|V SEC26 SECretory 973.0 0 0 0 0 0.12077065127494513 P41810 0.9484469890594482 0.9504740238189696 0.02068740501999855 0.01593497022986412 50.098587674587975 35.0 0.0 no 2433 chrIV_940351 7467 essential YDR238C 446 - ACTTACGAACATATGCATGA K|155|N silent|AAG>AAA|K|155 R|154|P R|154|H SEC26 SECretory 973.0 0 0 0 0 0.07419493960920998 P41810 0.9355990290641784 0.9099509716033936 0.9570810198783876 0.01227232813835144 0.0 0.0 1.8323999643325808 40.23082911947557 35.0 0.0 no 2434 chrIV_940536r 7470 essential YDR238C 258 + GTTCCCAAACTAGCTGAAGA P|88|A P|88|S P|88|R P|88|L SEC26 SECretory 973.0 0 0 0 0 -1.4711688351094452 P41810 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.033066526055336005 0.02173314057290554 0.060001857578754425 0.007837757468223572 47.043297814965285 45.0 0.0 no 2435 chrIV_940629 7471 essential YDR238C 168 - TGCATCAACAATTCAGGCAT M|62|I M|62|I L|61|F silent|TTG>TTA|L|61 SEC26 SECretory 973.0 0 0 0 0 0.2857427549897308 P41810 0.9553959965705872 0.9553959965705872 0.9587849974632264 0.09106141328811647 0.09106141328811647 0.07177487760782242 45.15106420050978 40.0 0.0 no 2436 chrIV_940718 7473 essential YDR238C 79 - TTCAAGAGCTTTCTGAAAAT E|33|Q E|33|K SEC26 SECretory 973.0 0 0 0 0 1.2971191272881193 P41810 0.956179976463318 0.9475290179252625 0.11425699293613435 0.0100117027759552 37.28368382183953 30.0 0.0 no 2437 chrIV_940756r 7475 essential YDR238C 38 + TTTCGATCCTTCTCCGAGTA F|14|L silent|TTC>TTT|F|14 SEC26 SECretory 973.0 0 0 0 0 -2.2955638832763823 P41810 0.9387490153312684 0.6465863585472107 52.1505914577017 45.0 0.0 yes 2438 chrIV_944065 7476 essential YDR240C 1068 - CTTCCGTCCTCAAAAGTTTT G|362|A G|362|E G|362|R G|362|R 0 0 0 0 -0.3082823442021968 Q03782 0.4216742217540741 0.032315798103809364 0.02198351733386517 0.02198351733386517 47.512703045596886 40.0 0.0 no 2439 chrIV_944088r 7478 essential YDR240C 1042 + ATTCTTCCAATCGTCATTCC S|349|C S|349|F S|350|C S|350|F 0 0 0 0 -0.8533803242839462 Q03782 0.11381485313177107 0.3356614112854004 0.07881778478622438 0.10065367072820663 49.306495196045034 40.0 0.0 no 2440 chrIV_944377r 7481 essential YDR240C 753 + GAACTTCCATTAATTGGCGA L|253|V L|253|F P|254|A P|254|S 0 0 0 0 0.4138110310347188 Q03782 0.5411709547042847 0.2911593317985535 1.0 0.7913212776184082 44.50722191683786 40.0 0.0 no 2441 chrIV_944371 7483 essential YDR240C 762 - AACAAGCCATCGCCAATTAA L|260|F silent|TTG>TTA|L|260 G|259|A G|259|D 0 0 0 0 0.2906076762719707 Q03782 0.0282672680914402 0.7810639739036559 0.4416670799255371 44.500560548843744 40.0 0.0 no 2442 chrIV_944383r 7484 essential YDR240C 747 + CTCTACGAACTTCCATTAAT silent|CTC>CTG|L|250 silent|CTC>CTT|L|250 Y|251|* silent|TAC>TAT|Y|251 0 0 0 0 -0.13697219286466628 Q03782 41.69622472949635 35.0 0.0 no 2443 chrIV_944583 7486 essential YDR240C 550 - AACTTCTACAATACTGGATG V|190|L V|190|I E|189|Q E|189|K 0 0 0 0 0.5295839437951161 Q03782 0.39174625277519226 0.6092818379402161 0.2837832570075989 0.5193412899971008 38.229038756471034 35.0 0.0 no 2444 chrIV_944615 7487 essential YDR240C 518 - TTCTATAGCTTGTTATTATA R|179|T R|179|K 0 0 0 0 0.0894807587040505 Q03782 0.29277396202087397 1.0 37.863874293802326 20.0 0.0 no 2445 chrIV_944640 7488 essential YDR240C 493 - TCTACCAGTTTCTATATTCT R|171|T R|171|K G|170|A G|170|D 0 0 0 0 -0.18383449093833293 Q03782 0.6050295233726501 0.8463211059570312 0.7357173562049866 0.6325705051422119 44.97050214049261 30.0 0.0 no 2446 chrIV_944641 7489 essential YDR240C 492 - CTACCAGTTTCTATATTCTT G|170|A G|170|D G|170|R G|170|S 0 0 0 0 1.1431553078733383 Q03782 0.7357173562049866 0.6325705051422119 0.5608236193656921 0.7199733853340149 44.190844453563614 30.0 0.0 no 2447 chrIV_944677 7491 essential YDR240C 456 - CCTGTCAAGTTAATATTCTT G|159|R G|159|S L|157|F silent|TTG>TTA|L|157 0 0 0 0 0.3516054550659806 Q03782 0.0 0.0 0.06687537580728531 41.65443615203702 30.0 0.0 no 2448 chrIV_944798r 7497 essential YDR240C 332 + GCTTTTCTACATAGTTTTGA L|112|V L|112|F F|113|L silent|TTC>TTT|F|113 0 0 0 0 -0.06182015156996309 Q03782 0.5501894354820251 0.7116027474403381 0.6213997602462769 43.41805166207661 30.0 0.0 no 2449 chrIV_944827 7498 essential YDR240C 306 - TCATCTTTCTGCTCTTTCTG E|109|Q E|109|K D|108|H D|108|N 0 0 0 0 0.2264993997425499 Q03782 0.4113328158855438 0.6583008170127869 0.16218943893909454 0.5194919109344482 49.78166312128325 40.0 0.0 no 2450 chrIV_944894r 7499 essential YDR240C 236 + ACAACAGTTCGACGAGTGCA Q|80|E Q|80|* Q|81|E Q|81|* 0 0 0 0 0.7513282681051491 Q03782 1.0 1.0 47.790570460678 50.0 0.0 no 2451 chrIV_945048 7502 essential YDR240C 85 - CTTCCTTCTTTGGCCATCAT R|34|S silent|AGG>AGA|R|34 R|34|T R|34|K 0 0 0 0 -0.7913623254927571 Q03782 0.11131055653095244 0.2865705490112305 0.8363479375839233 55.325864039289854 45.0 0.0 no 2452 chrIV_945061r 7503 essential YDR240C 69 + TATCCTACGACATCCAATGA P|25|A P|25|S P|25|R P|25|L 0 0 0 0 0.6117157077482317 Q03782 45.17819703843196 40.0 0.0 no 2453 chrIV_945124 7507 essential YDR240C 9 - TACGCTAATCCTCTCCTTCT silent|GCG>GCC|A|9 silent|GCG>GCA|A|9 A|9|P A|9|T 0 0 0 0 -0.046700522201730786 Q03782 52.8701265725901 45.0 0.0 no 2454 chrIV_945125 7509 essential YDR240C 8 - ACGCTAATCCTCTCCTTCTT A|9|P A|9|T silent|GCG>GCC|A|9 silent|GCG>GCA|A|9 0 0 0 0 0.4643975788946907 Q03782 53.70212948196848 45.0 0.0 no 2455 chrIV_949038 7511 essential YDR243C 1227 - TCCACAACCTGTTGAATCAA silent|GTG>GTC|V|415 silent|GTG>GTA|V|415 E|416|Q E|416|K PRP28 Pre-mRNA Processing 588.0 0 0 0 0 1.0712352047107767 P23394 0.1961025446653366 0.07666689902544023 -1.0329999923706057 -0.8378000259399414 44.920894955834 40.0 0.0 no 2456 chrIV_949039r 7512 essential YDR243C 1223 + ACCTTTGATTCAACAGGTTG P|409|R P|409|L P|409|A P|409|S PRP28 Pre-mRNA Processing 588.0 0 0 0 0 -0.18379206788403785 P23394 0.041864287108182914 0.03299462050199509 0.14836330711841586 0.08381008356809616 1.2120599746704102 0.4697000086307526 1.2727999687194824 1.8427000045776367 45.091517298128004 40.0 0.0 no 2457 chrIV_949080r 7517 essential YDR243C 1182 + AAGCCTGTTTATGCAACCAT P|396|A P|396|S P|396|R P|396|L PRP28 Pre-mRNA Processing 588.0 0 0 0 0 1.538938084040808 P23394 0.025242628529667854 0.015420527197420597 0.008196951821446419 0.005787849426269531 2.368259906768799 2.534980058670044 3.909339904785156 3.307339906692505 48.41654669244849 40.0 0.0 no 2458 chrIV_949442r 7525 essential YDR243C 820 + CACAAAAAGTTACAAAAATA Q|275|E Q|275|* PRP28 Pre-mRNA Processing 588.0 0 0 0 0 0.06756189252852471 P23394 1.0 -0.07633999735116959 26.94689089008648 20.0 0.0 no 2459 chrIV_949479 7526 essential YDR243C 786 - TGCTGCACTAATTCCCTTGT Q|268|H silent|CAG>CAA|Q|268 silent|GTG>GTC|V|267 silent|GTG>GTA|V|267 PRP28 Pre-mRNA Processing 588.0 0 0 0 0 0.22717394590059484 P23394 0.0 0.7290400266647339 53.32969562744546 45.0 0.0 no 2460 chrIV_949501 7527 essential YDR243C 764 - GAGCTAAAATTAACGCTTTG A|261|P A|261|T PRP28 Pre-mRNA Processing 588.0 0 0 0 0 0.5466776400087963 P23394 0.016503095626831055 0.02666980773210525 3.7050800323486333 1.0587600469589231 4.034200191497804 2.265399932861328 37.43187933457097 35.0 0.0 no 2461 chrIV_949536 7531 essential YDR243C 729 - TTCAAAGATGGTGGCCTTGG L|249|F silent|TTG>TTA|L|249 PRP28 Pre-mRNA Processing 588.0 0 0 0 0 -0.7369816047809319 P23394 0.3370587229728699 0.8575199842453003 -0.3702000081539154 49.19142241592806 50.0 0.0 no 2462 chrIV_949601 7533 essential YDR243C 664 - AGTCTTACCCGAACCTGTAG K|227|N silent|AAG>AAA|K|227 PRP28 Pre-mRNA Processing 588.0 0 0 0 0 -3.7310034112604775 P23394 0.0 1.4873199462890625 51.29494667009385 50.0 0.0 yes 2463 chrIV_949614r 7534 essential YDR243C 648 + TTTCTTGGTGTTGCCTCTAC L|218|V L|218|F PRP28 Pre-mRNA Processing 588.0 0 0 0 0 0.9605855594778364 P23394 0.2735059559345245 0.024415453895926482 2.026900053024292 3.1282200813293457 53.24158134601606 45.0 0.0 no 2464 chrIV_949755 7535 essential YDR243C 510 - AGCTCTTCCCAATTTCTCAA E|176|D silent|GAG>GAA|E|176 E|176|Q E|176|K PRP28 Pre-mRNA Processing 588.0 0 0 0 0 0.4563009333373421 P23394 0.1109168753027916 0.015762314200401306 0.012265218421816826 0.692520022392273 1.3075400590896606 1.4252599477767944 50.41716819166868 40.0 0.0 no 2465 chrIV_949838 7537 essential YDR243C 427 - TCTCTCATTCATTTCGTGCA E|148|D silent|GAG>GAA|E|148 R|149|T R|149|K PRP28 Pre-mRNA Processing 588.0 0 0 0 0 -0.788177445796223 P23394 0.5651090741157532 0.00743492878973484 0.13480712473392487 0.7434200048446655 0.5876799821853638 -0.16053999960422516 50.252875113080854 40.0 0.0 no 2466 chrIV_949880r 7540 essential YDR243C 382 + CTGCAGAATCTTCATATATG A|129|G A|129|V PRP28 Pre-mRNA Processing 588.0 0 0 0 0 -0.3372152889559272 P23394 0.4536955654621124 0.5822854042053223 39.94233922143741 35.0 0.0 no 2467 chrIV_952841r 7554 high_effect YDR245W 44 - CATCTTCATCGTACTCTAGA D|21|H D|21|N E|20|Q E|20|K MNN10 MaNNosyltransferase 393.0 0 1 0 0 0.13452627122744126 P50108 0.9899479746818542 1.0004899501800537 1.0004899501800537 0.9891330003738404 45.93404773349693 40.0 1.0 no 2468 chrIV_953025 7555 high_effect YDR245W 225 + CCATCTACCACAAGTTTTCA P|76|R P|76|L S|77|C S|77|F MNN10 MaNNosyltransferase 393.0 0 0 0 0 0.05424051460608287 P50108 0.9753050208091736 0.9834169745445251 0.920378029346466 0.9028819799423218 0.12273786216974257 0.10834822803735733 0.10784583538770676 0.0901401713490486 48.1017063944214 40.0 1.0 no 2469 chrIV_953025r 7556 high_effect YDR245W 228 - CCTTGAAAACTTGTGGTAGA G|83|R G|83|S MNN10 MaNNosyltransferase 393.0 0 0 0 0 0.6321515399898898 P50108 0.8943480253219604 0.9106770157814026 0.23961684107780454 0.5951460003852844 42.5471978313621 40.0 1.0 no 2470 chrIV_953115r 7557 high_effect YDR245W 318 - CATCTTGATCTCTTAGAATA R|112|T R|112|K MNN10 MaNNosyltransferase 393.0 0 0 0 0 -0.2537873796727812 P50108 0.9564380049705504 0.9748079776763916 0.6888318657875061 0.8692500591278076 39.10482944280858 30.0 1.0 no 2471 chrIV_953417r 7564 high_effect YDR245W 620 - GCTCCATTATCATAGTATCC E|213|Q E|213|K E|213|D silent|GAG>GAA|E|213 MNN10 MaNNosyltransferase 393.0 0 0 0 0 -0.3991790119403577 P50108 0.9594100117683412 0.9491919875144958 0.9537240266799928 0.059037629514932626 0.038641087710857384 0.14966389536857605 49.387349300243386 40.0 1.0 no 2472 chrIV_953538r 7566 high_effect YDR245W 741 - TCCTCTGAATAATCGACATA E|253|D silent|GAG>GAA|E|253 E|254|Q E|254|K MNN10 MaNNosyltransferase 393.0 0 0 0 0 -0.06517914088161142 P50108 0.9317309856414796 0.9413359761238098 0.92774897813797 0.39086073637008667 0.2228383272886276 0.2692795991897583 41.11713582355157 35.0 1.0 no 2473 chrIV_953638 7567 high_effect YDR245W 838 + AGCTGCTTCTAGATATGTGG L|281|V silent|CTG>TTG|L|281 L|282|V L|282|F MNN10 MaNNosyltransferase 393.0 0 0 0 0 0.08383699552025163 P50108 0.9577580094337464 0.9320489764213562 0.943248987197876 0.4987601935863495 0.06936275213956833 0.008185901679098606 48.654196678157575 45.0 1.0 no 2474 chrIV_954352r 7572 essential YDR246W 67 - GTTCAATTTCTGTTCGTCGT L|28|F silent|TTG>TTA|L|28 TRS23 TRapp Subunit 219.0 0 0 0 0 0.9184248907706052 Q03784 0.07833664864301683 0.05660000070929527 48.54832502194745 40.0 1.0 no 2475 chrIV_954390 7573 essential YDR246W 102 + ATTCTTGCTAGTACACTGCA L|36|V L|36|F TRS23 TRapp Subunit 219.0 0 0 0 0 -0.909094542629902 Q03784 0.024911053478717804 0.13125936686992645 1.4522000551223757 0.7824000120162964 48.73167110482161 40.0 1.0 no 2476 chrIV_954485 7576 essential YDR246W 197 + CATCCCATATATACCTTACG I|67|M silent|ATC>ATT|I|67 P|68|A P|68|S TRS23 TRapp Subunit 219.0 0 0 0 0 0.1872961433593284 Q03784 0.0832260325551033 0.8582577705383301 0.7357165217399597 -0.2142000049352646 46.208573265257826 40.0 1.0 no 2477 chrIV_954498r 7578 essential YDR246W 213 - TTGCTGGACATGCCCACGTA S|77|T S|77|N TRS23 TRapp Subunit 219.0 0 0 0 0 0.12757703976454826 Q03784 0.5970605611801147 0.5701560378074646 1.9414000511169436 -0.3826000094413757 56.00834858255024 55.00000000000001 1.0 no 2478 chrIV_954607 7582 essential YDR246W 319 + TCAAAGAACCATTTACGAAC F|107|L silent|TTC>TTT|F|107 TRS23 TRapp Subunit 219.0 0 0 0 0 -0.6598049992831339 Q03784 0.22278685867786407 -0.026200000196695328 36.67248176444025 35.0 1.0 no 2479 chrIV_954689r 7584 essential YDR246W 404 - CGACAAACTTCAGGCCGGTT V|141|L V|141|I TRS23 TRapp Subunit 219.0 0 0 0 0 -0.2647268426920518 Q03784 0.9008964896202089 0.39059779047966 50.93958620892192 55.00000000000001 1.0 no 2480 chrIV_954698r 7586 essential YDR246W 413 - AGCTGATAGCGACAAACTTC S|144|T S|144|N TRS23 TRapp Subunit 219.0 0 0 0 0 0.5429533452371842 Q03784 1.0 0.23278957605361936 43.814020664576 45.0 1.0 no 2481 chrIV_954777r 7589 essential YDR246W 492 - GCCAAATTGGATGTACTCTT L|170|F silent|TTG>TTA|L|170 A|171|P A|171|T TRS23 TRapp Subunit 219.0 0 0 0 0 -0.2792751909261577 Q03784 0.3709399700164795 0.2695958316326141 0.550274670124054 -0.2272000014781952 -1.0770000219345093 0.8245999813079834 46.10681550285699 40.0 1.0 no 2482 chrIV_975220 7593 no_effect YDR259C 543 - TCAGCACTGTTTTGAAAAGA D|188|H D|188|N A|187|P A|187|T 0 0 0 0 -0.19643520820442384 Q03935 0.01611836440861225 0.11606787145137787 0.3001135289669037 0.551966667175293 40.10716695318018 35.0 0.0 no 2483 chrIV_975254 7595 no_effect YDR259C 509 - TAACACTGGTATTGCGAGAT V|176|L V|176|I S|175|T S|175|N 0 0 0 0 0.6220676576049693 Q03935 0.6685187220573425 0.4315023720264435 0.2635921835899353 0.15531808137893674 43.197003383743954 40.0 0.0 no 2484 chrIV_975325 7598 no_effect YDR259C 438 - CTCTGGTTCGGAAGTCCATT Q|152|H silent|CAG>CAA|Q|152 0 0 0 0 0.3125733176798927 Q03935 0.2151160091161728 52.44231666395632 50.0 0.0 no 2485 chrIV_975308 7599 no_effect YDR259C 455 - CCTTATTCAAAGATATGCTC K|158|N silent|AAG>AAA|K|158 0 0 0 0 -0.22010943574391767 Q03935 0.4457998275756836 41.31012521304365 35.0 0.0 no 2486 chrIV_975466 7601 no_effect YDR259C 297 - TTTCTTTCATTTGAATGCGG R|105|T R|105|K 0 0 0 0 0.5714888471478932 Q03935 0.27299779653549194 0.7055734992027283 42.870319120285394 35.0 0.0 no 2487 chrIV_975421 7602 no_effect YDR259C 342 - ATACTAACATGAGCATTTTG S|120|T S|120|N 0 0 0 0 -0.6135251321042988 Q03935 0.23316259682178495 0.13961762189865112 37.72601492448649 30.0 0.0 no 2488 chrIV_975544r 7606 no_effect YDR259C 216 + CCAAACTTGATGCATCTATC P|73|R P|73|L N|74|K silent|AAC>AAT|N|74 0 0 0 0 0.4702764194184059 Q03935 43.295690228289224 40.0 0.0 no 2489 chrIV_975735 7611 no_effect YDR259C 28 - GCTTCCCTGATTATACATAT S|16|T S|16|N G|15|A G|15|E 0 0 0 0 0.240143681614362 Q03935 46.98813888846587 35.0 0.0 no 2490 chrIV_995299r 7624 no_effect YDR263C 213 + AAGCCATATATAGTTTTTGA P|73|A P|73|S P|73|R P|73|L 0 0 0 0 0.32128996191060755 Q12086 0.0 0.0 0.0 0.0 39.69405258965843 25.0 0.0 no 2491 chrIV_995430 7625 no_effect YDR263C 85 - TAGCCACGCATAACCATCAA W|34|C W|34|* W|34|S W|34|* 0 1 0 0 0.017231225392051568 Q12086 0.0 0.0 48.10466325423272 45.0 0.0 no 2492 chrIV_996721r 7630 high_effect YDR264C 1580 + CACATTTCTTGCACTTTGCC T|528|R T|528|I AKR1 AnKyrin Repeat containing 764.0 0 0 0 0 0.15608937361876624 P39010 0.9476869702339172 0.9472420215606691 0.3857091665267944 0.466875433921814 51.209023907672126 45.0 0.0 no 2493 chrIV_996801 7631 high_effect YDR264C 1503 - CCGACATCATTAAAGATCCA G|508|R G|508|R V|507|L V|507|I AKR1 AnKyrin Repeat containing 764.0 0 0 0 0 -2.217502812716288 P39010 0.941340982913971 0.941340982913971 0.9539830088615416 0.9574310183525084 0.0 0.0 0.08824019879102707 1.0 43.71612224929163 40.0 0.0 yes 2494 chrIV_996801r 7632 high_effect YDR264C 1500 + CCTTGGATCTTTAATGATGT P|501|R P|501|L AKR1 AnKyrin Repeat containing 764.0 0 1 0 0 0.7229614957843172 P39010 0.9432820081710817 0.9430609941482544 0.0 0.0 43.70984585625729 35.0 0.0 no 2495 chrIV_996842 7633 high_effect YDR264C 1462 - TGCAACCACAGCATTGTTTA A|494|P A|494|T V|493|L V|493|I AKR1 AnKyrin Repeat containing 764.0 0 0 0 0 -0.06987930820467486 P39010 0.9573720097541808 0.9523990154266356 0.9539830088615416 0.9574310183525084 0.2955822348594665 0.992210566997528 0.07118157297372818 0.6258915066719055 47.74407029025804 40.0 0.0 no 2496 chrIV_996843 7634 high_effect YDR264C 1461 - GCAACCACAGCATTGTTTAA A|494|P A|494|T V|493|L V|493|I AKR1 AnKyrin Repeat containing 764.0 0 0 0 0 -0.5173010674584191 P39010 0.9573720097541808 0.9523990154266356 0.9539830088615416 0.9574310183525084 0.2955822348594665 0.992210566997528 0.07118157297372818 0.6258915066719055 46.21791069543377 40.0 0.0 no 2497 chrIV_996933r 7636 high_effect YDR264C 1368 + ATCTCGAACTTGCTCGAAAT I|457|M silent|ATC>ATT|I|457 S|458|W S|458|L AKR1 AnKyrin Repeat containing 764.0 0 0 0 0 0.8533326540269045 P39010 0.9598389863967896 0.9288619756698608 0.9298099875450134 0.009229576215147972 0.014044549316167831 0.21053417026996613 42.48528360816999 40.0 0.0 no 2498 chrIV_996982 7637 high_effect YDR264C 1322 - TTTCTTCTGGCAAACATCCT E|447|Q E|447|K E|446|Q E|446|K AKR1 AnKyrin Repeat containing 764.0 0 0 0 0 0.11016316435625872 P39010 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.5203204154968262 0.7963632941246033 0.5896074175834656 0.9291784763336182 48.31057506863527 40.0 0.0 no 2499 chrIV_997160 7640 high_effect YDR264C 1144 - TAACAAAGGTGACCTTAACA L|387|F silent|TTG>TTA|L|387 AKR1 AnKyrin Repeat containing 764.0 0 0 0 0 1.447706127643139 P39010 0.9587849974632264 1.0 38.66180532847096 35.0 0.0 no 2500 chrIV_997172r 7642 high_effect YDR264C 1129 + TCCACAACGTTACCTTGTTA H|378|D H|378|Y silent|GTC>GTG|V|377 silent|GTC>GTT|V|377 AKR1 AnKyrin Repeat containing 764.0 0 0 0 0 -0.1863282292853512 P39010 0.9473130106925964 0.9489949941635132 0.13529065251350406 0.7330358028411865 47.97233622042103 40.0 0.0 no 2501 chrIV_997198r 7643 high_effect YDR264C 1103 + TCTGCCGTCATATGGACGAA L|369|V silent|CTG>TTG|L|369 P|370|A P|370|S AKR1 AnKyrin Repeat containing 764.0 0 0 0 0 0.8251535840916592 P39010 0.9512209892272948 0.9562489986419678 0.9498909711837769 0.4249433875083923 0.0 0.0 49.61116907700064 50.0 0.0 no 2502 chrIV_997314 7644 high_effect YDR264C 990 - GCGATTCCTAGAAATAGAAA A|337|P A|337|T G|335|A G|335|E AKR1 AnKyrin Repeat containing 764.0 0 0 0 0 -0.9435595026184568 P39010 0.9573720097541808 0.9523990154266356 0.9499930143356324 0.9438679814338684 0.08147649466991425 0.2415372133255005 1.0 0.13690823316574094 38.25015404170301 35.0 0.0 no 2503 chrIV_997621 7650 high_effect YDR264C 683 - TCAACAATTCTGCTACAGTT L|234|F silent|TTG>TTA|L|234 L|233|F silent|TTG>TTA|L|233 AKR1 AnKyrin Repeat containing 764.0 0 0 0 0 -1.1459199050292872 P39010 0.9587849974632264 0.9587849974632264 0.0 0.0 42.7937102564203 35.0 0.0 no 2504 chrIV_997622 7651 high_effect YDR264C 682 - CAACAATTCTGCTACAGTTA L|233|F silent|TTG>TTA|L|233 AKR1 AnKyrin Repeat containing 764.0 0 0 0 0 -0.11182926851987336 P39010 0.9587849974632264 0.0 41.30025904478117 35.0 0.0 no 2505 chrIV_997797r 7658 high_effect YDR264C 504 + CCCACCATGACCGATGACCA silent|CCC>CCG|P|169 silent|CCC>CCT|P|169 P|169|R P|169|L AKR1 AnKyrin Repeat containing 764.0 0 0 0 0 -0.5145814467061143 P39010 0.9432820081710817 0.9430609941482544 0.0 0.0 56.712631263403175 60.0 0.0 no 2506 chrIV_997862r 7659 high_effect YDR264C 439 + TACATTGGGCTGCAAGGTAT H|148|D H|148|Y AKR1 AnKyrin Repeat containing 764.0 0 0 0 0 -0.6712562349623713 P39010 0.9473130106925964 0.9489949941635132 0.0 0.0 48.8573447876467 45.0 0.0 no 2507 chrIV_997876r 7661 high_effect YDR264C 425 + GCATGCCACACCATTACATT H|143|D H|143|Y A|144|G A|144|V AKR1 AnKyrin Repeat containing 764.0 0 0 0 0 -0.3653085522039992 P39010 0.9473130106925964 0.9489949941635132 0.9484469890594482 0.9504740238189696 0.9845622777938844 0.0997883602976799 0.0 0.0 51.76233284978366 45.0 0.0 no 2508 chrIV_997989r 7663 high_effect YDR264C 312 + GACTCTACGGAACATATCAC D|105|E silent|GAC>GAT|D|105 S|106|C S|106|F AKR1 AnKyrin Repeat containing 764.0 0 0 0 0 -1.0339820020728068 P39010 0.9532920122146606 0.945252001285553 0.9294660091400146 0.4051384925842285 0.06961351633071901 0.13229317963123322 42.71688134943582 45.0 0.0 no 2509 chrIV_997979r 7664 high_effect YDR264C 322 + AACATATCACTGGTTTGCAT H|109|D H|109|Y AKR1 AnKyrin Repeat containing 764.0 0 0 0 0 0.7502354002598695 P39010 0.9473130106925964 0.9489949941635132 0.5374197363853455 0.04936990886926651 43.85280608250696 35.0 0.0 no 2510 chrIV_998155 7668 high_effect YDR264C 149 - TTTCCTCTTCATTTCCTGAT E|56|Q E|56|K E|55|D silent|GAG>GAA|E|55 AKR1 AnKyrin Repeat containing 764.0 0 1 0 0 -0.7675797809460408 P39010 0.956179976463318 0.9475290179252625 0.94931298494339 0.5767836570739746 0.9023656845092772 0.6297670006752014 50.400599513568636 35.0 0.0 no 2511 chrIV_998169r 7669 high_effect YDR264C 132 + TCATTAAAGGCTATCCGATC S|45|* S|45|L AKR1 AnKyrin Repeat containing 764.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.9325833809726952 P39010 0.9298099875450134 0.12265842407941817 43.83261846956623 40.0 0.0 no 2512 chrIV_998194r 7672 high_effect YDR264C 107 + TTCTAACGAAATTACTTCGT S|37|C S|37|F N|38|K silent|AAC>AAT|N|38 AKR1 AnKyrin Repeat containing 764.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.21061069164792456 P39010 0.945252001285553 0.9294660091400146 0.9439849853515624 0.039358265697956085 0.03840263187885285 0.8681600093841553 37.62885268341761 30.0 0.0 no 2513 chrIV_1002746 7677 essential YDR267C 737 - CCTGTCTTTTGTGTACATCC Q|252|H silent|CAG>CAA|Q|252 R|251|T R|251|K CIA1 Cytosolic Iron-sulfur protein Assembly 330.0 0 0 0 0 -0.2446526144796703 Q05583 0.9570760130882264 0.932735025882721 0.955805003643036 0.0298518929630518 0.022681770846247677 0.2130894660949707 -0.7056599855422974 1.7096199989318848 -0.8021600246429443 -4.144999980926514 -0.6173999905586243 52.559899514017275 45.0 0.0 no 2514 chrIV_1002745 7678 essential YDR267C 738 - ACCTGTCTTTTGTGTACATC Q|252|H silent|CAG>CAA|Q|252 V|253|L V|253|I CIA1 Cytosolic Iron-sulfur protein Assembly 330.0 0 0 0 0 0.22148159002112847 Q05583 0.9570760130882264 0.9539830088615416 0.9574310183525084 0.0298518929630518 0.04390144720673561 1.0 -0.7056599855422974 1.4264999628067017 0.4472799897193909 -0.8069999814033508 0.08240000158548355 49.03327233685457 40.0 0.0 no 2515 chrIV_1002874r 7684 essential YDR267C 606 + TCTGATTTTGACAAGACTGA S|203|C S|203|F CIA1 Cytosolic Iron-sulfur protein Assembly 330.0 0 0 0 0 -0.6161705077072714 Q05583 0.945252001285553 0.9294660091400146 0.09227340668439864 0.08876698464155197 -1.0203800201416016 18.482999801635746 40.194874757534535 35.0 0.0 no 2516 chrIV_1003241r 7692 essential YDR267C 239 + CACTGTATCTATCTGGGCTA T|81|S T|81|I CIA1 Cytosolic Iron-sulfur protein Assembly 330.0 0 0 0 0 -0.17882690496795467 Q05583 0.9491789937019348 0.9472420215606691 0.0 0.0 0.43281999230384827 0.1818999946117401 49.846423859666636 45.0 0.0 no 2517 chrIV_1002830r 7693 essential YDR267C 650 + AAGCGACGATTCCACTGTAC S|218|R silent|AGC>AGT|S|218 D|219|E silent|GAC>GAT|D|219 CIA1 Cytosolic Iron-sulfur protein Assembly 330.0 0 0 0 0 -4.230457702879947 Q05583 0.9417110085487366 0.9532920122146606 0.008152421563863754 0.15348781645298004 25.492919921875 0.05195999890565872 47.612374794375675 50.0 0.0 yes 2518 chrIV_1003414r 7698 essential YDR267C 66 + TCTCAAGGTATATTAGCAAC Q|24|E Q|24|* S|23|C S|23|F CIA1 Cytosolic Iron-sulfur protein Assembly 330.0 0 0 0 0 0.3327336426890713 Q05583 0.9590039849281312 0.945252001285553 0.9294660091400146 0.3174895942211151 0.02319570630788803 0.053877715021371834 0.11974000185728073 -0.26877999305725103 6.952040195465088 40.20736382768854 35.0 0.0 no 2519 chrIV_1020937 7706 essential YDR280W 190 + TAGCACAACCATACGAAGAC A|65|G A|65|V Q|66|E Q|66|* RRP45 Ribosomal RNA Processing 305.0 0 0 0 0 0.02966911098352415 Q05636 0.012215040624141691 0.2955436110496521 0.5743967294692993 0.724560022354126 0.720687985420227 0.4197399914264679 1.1727709770202637 0.783939003944397 42.28721369002716 45.0 1.0 no 2520 chrIV_1020983 7708 essential YDR280W 236 + ATCTACAGAAATATCTCCTA S|80|C S|80|F T|81|R T|81|I RRP45 Ribosomal RNA Processing 305.0 0 0 0 0 1.0035771045820374 Q05636 0.04192229732871056 0.0434400737285614 0.029617832973599437 0.13688962161540985 -0.5306280255317688 -2.085642099380493 2.081471920013428 -1.1759380102157593 39.812278837692475 30.0 1.0 no 2521 chrIV_1020945r 7709 essential YDR280W 201 - TCAAATGGCCTGTCTTCGTA E|74|Q E|74|K RRP45 Ribosomal RNA Processing 305.0 0 0 0 0 0.430792815372044 Q05636 0.04152628779411316 0.032389085739851005 -0.4238699972629547 -1.3522039651870728 49.88514485220464 45.0 1.0 no 2522 chrIV_1021236 7718 essential YDR280W 489 + AAACCAGATATAACTGTCCA P|165|A P|165|S P|165|R P|165|L RRP45 Ribosomal RNA Processing 305.0 0 0 0 0 0.6510947286391288 Q05636 0.0 0.0 0.0 0.0 1.84864604473114 1.9401140213012693 1.7790679931640625 1.0412640571594238 41.56719404116973 35.0 1.0 no 2523 chrIV_1021253r 7719 essential YDR280W 509 - GAACAATGATCTGCTCGCCA V|176|L V|176|I RRP45 Ribosomal RNA Processing 305.0 0 0 0 0 1.3405115967291656 Q05636 0.0330728180706501 0.3998286128044128 -1.3965740203857422 -0.8822680115699768 -1.2842615842819214 -1.0698260068893433 49.29771700499372 50.0 1.0 no 2524 chrIV_1021346 7721 essential YDR280W 599 + CTTCAATCCTCAAGACACCG F|201|L silent|TTC>TTT|F|201 RRP45 Ribosomal RNA Processing 305.0 0 0 0 0 0.7563863526467092 Q05636 0.0562378354370594 2.80757999420166 0.4850605428218842 47.7944486813513 50.0 1.0 no 2525 chrIV_1037652r 7729 essential YDR288W 460 - ATCGTCACCAATATACTCTC D|160|H D|160|N D|159|H D|159|N NSE3 Non SMC Element 303.0 0 0 0 0 0.17457788925169748 Q05541 0.05115775763988495 0.40977606177330017 0.08999940752983092 0.6524866223335266 -0.08699999749660492 -0.12700000405311584 45.27952749475594 40.0 1.0 no 2526 chrIV_1037691r 7730 essential YDR288W 499 - CAACTTGCTTTCTAAGGTAT K|172|N silent|AAG>AAA|K|172 NSE3 Non SMC Element 303.0 0 0 0 0 0.5871597898619166 Q05541 0.2228275090456009 -0.4293999969959259 42.65749959661764 35.0 1.0 no 2527 chrIV_1037834r 7732 essential YDR288W 642 - GCAATCTTTGAACCATCGCT A|221|P A|221|T K|219|N silent|AAG>AAA|K|219 NSE3 Non SMC Element 303.0 0 0 0 0 1.2103757241009458 Q05541 1.0 0.032295819371938705 0.44816020131111145 1.0937000513076782 48.69907056422471 45.0 1.0 no 2528 chrIV_1043752r 7735 essential YDR292C 1237 + ATCTTTCAAAGCTAGCGTTT L|414|V L|414|F S|415|* S|415|L SRP101 Signal Recognition Particle 621.0 0 0 0 0 0.029425013420215487 P32916 0.9512209892272948 0.9587849974632264 0.9298099875450134 0.0 0.0 0.0 44.76727813500185 35.0 0.0 no 2529 chrIV_1043801r 7738 essential YDR292C 1188 + CCCTATGTGTTCTCTATAGT silent|CCC>CCG|P|397 silent|CCC>CCT|P|397 P|397|R P|397|L SRP101 Signal Recognition Particle 621.0 0 0 0 0 0.930655242938722 P32916 0.9432820081710817 0.9430609941482544 0.0 0.0 51.03896085391273 40.0 0.0 no 2530 chrIV_1044584r 7744 essential YDR292C 405 + AACTACGTCGATATTCTTCA N|136|K silent|AAC>AAT|N|136 Y|137|* silent|TAC>TAT|Y|137 SRP101 Signal Recognition Particle 621.0 0 0 0 0 0.02987657340282496 P32916 0.9439849853515624 0.3518275916576385 0.1990779936313629 0.5023599863052368 42.17454390363434 35.0 0.0 no 2531 chrIV_1044687r 7747 essential YDR292C 302 + AACTCAACAAACACTTGCAC T|102|S T|102|I Q|103|E Q|103|* SRP101 Signal Recognition Particle 621.0 0 0 0 0 -0.5001959552317131 P32916 0.9491789937019348 0.9472420215606691 0.9590039849281312 0.8071093559265137 0.3920381665229797 1.0 2.755458116531372 -0.6949340105056763 0.523140013217926 39.595649305558936 40.0 0.0 no 2532 chrIV_1044869 7748 essential YDR292C 123 - ACACTTTCTTTTCTAGTTAC S|47|T S|47|N V|48|L V|48|I SRP101 Signal Recognition Particle 621.0 0 0 0 0 -0.49188314328835 P32916 0.9512869715690612 0.9536849856376648 0.9539830088615416 0.9574310183525084 0.5561566948890686 0.4788940250873566 0.7747292518615723 0.5092490911483765 0.3795520067214966 -0.0057299998588860035 -0.919875979423523 -0.4906159937381744 -0.5908600091934204 -0.6561800241470337 42.123085138124 30.0 0.0 no 2533 chrIV_1044870 7752 essential YDR292C 122 - CACTTTCTTTTCTAGTTACT S|47|T S|47|N E|46|Q E|46|K SRP101 Signal Recognition Particle 621.0 0 0 0 0 0.5056790444960224 P32916 0.9512869715690612 0.9536849856376648 0.956179976463318 0.9475290179252625 0.5561566948890686 0.4788940250873566 0.2328735440969467 0.249764546751976 0.3795520067214966 -0.0057299998588860035 0.985360026359558 0.582177996635437 43.635761183435925 30.0 0.0 no 2534 chrIV_1059858r 7757 essential YDR299W 234 - CCTTTAACACCTGTATATTT G|85|R G|85|S BFR2 BreFeldin A Resistance 534.0 0 0 0 0 0.5555860484459967 Q06631 0.941340982913971 0.951104998588562 0.058614321053028114 0.4299161434173584 43.169808690275715 30.0 1.0 no 2535 chrIV_1059910r 7758 essential YDR299W 286 - TTCTTCTTCGTCCTCATTCT E|102|Q E|102|K E|101|Q E|101|K BFR2 BreFeldin A Resistance 534.0 0 0 0 0 -0.16342324744695358 Q06631 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.2409094870090485 0.2259330302476883 0.5646846890449524 0.8339062333106995 53.04537205232453 40.0 1.0 no 2536 chrIV_1060244 7760 essential YDR299W 617 + CCCATTAACTACAGAGTCCT P|207|R P|207|L P|207|A P|207|S BFR2 BreFeldin A Resistance 534.0 0 0 0 0 0.18252541224787933 Q06631 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 50.25217305379146 45.0 1.0 no 2537 chrIV_1060359 7763 essential YDR299W 732 + TTCAGAATAAAATTCCAACT F|245|L silent|TTC>TTT|F|245 BFR2 BreFeldin A Resistance 534.0 0 1 0 0 -0.323364480875162 Q06631 0.9387490153312684 1.0 34.58086954148263 25.0 1.0 no 2538 chrIV_1060618r 7768 essential YDR299W 994 - TTTCATCAAACGGGACATAT M|337|I M|337|I L|336|F silent|TTG>TTA|L|336 BFR2 BreFeldin A Resistance 534.0 0 0 0 0 -0.9904772560581024 Q06631 0.9553959965705872 0.9553959965705872 0.9587849974632264 0.4667294025421143 0.4667294025421143 0.03383136913180351 40.461127221572326 35.0 1.0 no 2539 chrIV_1060726r 7769 essential YDR299W 1102 - ATCAACACTATCTTTGACAA D|374|H D|374|N V|373|L V|373|I BFR2 BreFeldin A Resistance 534.0 0 1 0 0 0.3998182744719869 Q06631 0.9486550092697144 0.956179976463318 0.9539830088615416 0.9574310183525084 0.1101783961057663 0.4929835796356201 0.3504121005535126 0.21660517156124115 38.38862388411144 30.0 1.0 no 2540 chrIV_1060749 7770 essential YDR299W 1122 + GACAATGAGAATTCGGATGA D|375|E silent|GAC>GAT|D|375 BFR2 BreFeldin A Resistance 534.0 0 1 0 0 -1.0373744093266244 Q06631 0.9532920122146606 1.0 39.30168363257326 40.0 1.0 no 2541 chrIV_1060781r 7772 essential YDR299W 1157 - TTCTTGGGTCATAGTTTTTC R|392|T R|392|K BFR2 BreFeldin A Resistance 534.0 0 0 0 0 -0.0383697948359345 Q06631 0.932735025882721 0.955805003643036 0.06551982462406157 0.3938872218132019 46.43660276887312 35.0 1.0 no 2542 chrIV_1060797r 7774 essential YDR299W 1173 - GCATTGTTATCCTTTCTTCT A|398|P A|398|T BFR2 BreFeldin A Resistance 534.0 0 0 0 0 -0.5424988709821914 Q06631 0.9573720097541808 0.9523990154266356 0.24468135833740234 0.8584223389625549 50.143810298661954 35.0 1.0 no 2543 chrIV_1063461 7775 essential YDR301W 109 + TTTCTGTCTACAGGCCTACT S|38|C S|38|F CFT1 Cleavage Factor Two 1357.0 0 0 0 0 0.3760615538610205 Q06632 0.945252001285553 0.9294660091400146 0.05020536482334137 0.038255497813224786 53.14925614443206 45.0 1.0 no 2544 chrIV_1063462 7776 essential YDR301W 110 + TTCTGTCTACAGGCCTACTA S|38|C S|38|F silent|GTC>GTG|V|39 silent|GTC>GTT|V|39 CFT1 Cleavage Factor Two 1357.0 0 0 0 0 -0.4076164726992654 Q06632 0.945252001285553 0.9294660091400146 0.05020536482334137 0.038255497813224786 52.25698675181593 45.0 1.0 no 2545 chrIV_1063475r 7778 essential YDR301W 126 - TACAGTTTACCATCCCTAGT silent|CTG>CTC|L|48 silent|CTG>CTA|L|48 CFT1 Cleavage Factor Two 1357.0 0 0 0 0 -1.5095185355572804 Q06632 51.29138587424171 40.0 1.0 no 2546 chrIV_1063551r 7781 essential YDR301W 202 - ACTTAACGGACTGTCTTTTT S|74|T S|74|N silent|CCG>CCC|P|72 silent|CCG>CCA|P|72 CFT1 Cleavage Factor Two 1357.0 0 0 0 0 -0.06827206501110528 Q06632 0.9512869715690612 0.9536849856376648 0.10384801775217056 0.14166635274887085 43.59539063818181 35.0 1.0 no 2547 chrIV_1063647r 7783 essential YDR301W 298 - TTCGTAGTAATGCAGGCTTA E|106|Q E|106|K CFT1 Cleavage Factor Two 1357.0 0 0 0 0 0.8551475300335676 Q06632 0.956179976463318 0.9475290179252625 0.02723161317408085 0.021528849378228188 46.838895866402474 40.0 1.0 no 2548 chrIV_1063661 7787 essential YDR301W 309 + TACTACGAAGGAAAGTTCAA Y|104|* silent|TAC>TAT|Y|104 Y|105|* silent|TAC>TAT|Y|105 CFT1 Cleavage Factor Two 1357.0 0 0 0 0 -2.7443592869260405 Q06632 36.66054649365845 35.0 1.0 yes 2549 chrIV_1063716r 7789 essential YDR301W 367 - ACTTCCAGGATCCATTCTCA S|129|T S|129|N G|128|A G|128|E CFT1 Cleavage Factor Two 1357.0 0 0 0 0 -0.8323828229941872 Q06632 0.9512869715690612 0.9536849856376648 0.9499930143356324 0.9438679814338684 0.3898111283779144 1.0 0.7666210532188416 1.0 53.37750259790329 45.0 1.0 no 2550 chrIV_1064041 7794 essential YDR301W 689 + ATACCAACCAAAGCTTGTTT Y|231|* silent|TAC>TAT|Y|231 Q|232|E Q|232|* CFT1 Cleavage Factor Two 1357.0 0 0 0 0 -0.9421051303858754 Q06632 0.9590039849281312 0.4448601007461548 44.170841861544545 35.0 1.0 no 2551 chrIV_1064044r 7795 essential YDR301W 695 - CTGCCCAAACAAGCTTTGGT A|238|P A|238|T W|237|C W|237|* CFT1 Cleavage Factor Two 1357.0 0 0 0 0 -0.099834233242224 Q06632 0.9573720097541808 0.9523990154266356 0.8858469724655151 0.059556066989898675 0.05991413071751595 0.0 51.369980985662316 50.0 1.0 no 2552 chrIV_1064198 7799 essential YDR301W 846 + ACCATTGTACCTGTTTCGAA silent|ACC>ACG|T|283 silent|ACC>ACT|T|283 T|283|S T|283|I CFT1 Cleavage Factor Two 1357.0 0 0 0 0 -1.405698807008948 Q06632 0.9491789937019348 0.9472420215606691 0.5417386293411255 0.1670272946357727 47.96541656261292 40.0 1.0 no 2553 chrIV_1064212 7800 essential YDR301W 860 + TTCGAATGGTGCTATCATTG S|288|W S|288|L CFT1 Cleavage Factor Two 1357.0 0 0 0 0 0.6040739819246259 Q06632 0.9288619756698608 0.9298099875450134 0.007385528180748223 0.031568683683872216 43.76901746572855 40.0 1.0 no 2554 chrIV_1064400r 7806 essential YDR301W 1051 - ACTTCCTCCGTTTTTGCTCT S|357|T S|357|N G|356|A G|356|E CFT1 Cleavage Factor Two 1357.0 0 0 0 0 1.439094403732645 Q06632 0.9512869715690612 0.9536849856376648 0.9499930143356324 0.9438679814338684 56.664322383700956 45.0 1.0 no 2555 chrIV_1064396 7807 essential YDR301W 1044 + TCGTCCAAGAGCAAAAACGG S|349|W S|349|L S|350|C S|350|F CFT1 Cleavage Factor Two 1357.0 0 0 0 0 -0.08691662662035182 Q06632 0.9288619756698608 0.9298099875450134 0.945252001285553 0.9294660091400146 43.101313583952894 50.0 1.0 no 2556 chrIV_1064476r 7809 essential YDR301W 1127 - ACCTGCCCTCTGCTTCCATT R|382|T R|382|K R|382|S silent|AGG>AGA|R|382 CFT1 Cleavage Factor Two 1357.0 0 0 0 0 0.511917920130311 Q06632 0.932735025882721 0.955805003643036 0.9087679982185364 0.08227257430553436 1.0 0.07345104217529297 63.23004729702564 55.00000000000001 1.0 no 2557 chrIV_1064528r 7810 essential YDR301W 1179 - TTCAAAAGATCATTGACTAT L|399|F silent|TTG>TTA|L|399 CFT1 Cleavage Factor Two 1357.0 0 0 0 0 0.8547576220347674 Q06632 0.9587849974632264 0.7171675562858582 34.36523421407878 25.0 1.0 no 2558 chrIV_1064564r 7812 essential YDR301W 1215 - TTCAAACGTGTTATACATTT L|411|F silent|TTG>TTA|L|411 R|410|P R|410|H CFT1 Cleavage Factor Two 1357.0 0 0 0 0 0.3464494576202815 Q06632 0.9587849974632264 0.9099509716033936 0.9570810198783876 0.036702193319797516 0.2812258005142212 0.5679137110710144 37.15281264910675 25.0 1.0 no 2559 chrIV_1064811r 7817 essential YDR301W 1462 - AACAGTTTCCACAGTGCCTT V|494|L V|494|I CFT1 Cleavage Factor Two 1357.0 0 0 0 0 1.1332628727665488 Q06632 0.9539830088615416 0.9574310183525084 0.3065973222255707 0.19123464822769165 52.77288106989765 45.0 1.0 no 2560 chrIV_1064879 7818 essential YDR301W 1527 + CCCATCACATCGTTAACTGT silent|CCC>CCG|P|510 silent|CCC>CCT|P|510 P|510|R P|510|L CFT1 Cleavage Factor Two 1357.0 0 0 0 0 -0.5330410091701943 Q06632 0.9432820081710817 0.9430609941482544 0.0 0.0 49.75597809469906 45.0 1.0 no 2561 chrIV_1065114 7823 essential YDR301W 1762 + CTACTGATTCCACAAAATCC T|589|S T|589|I CFT1 Cleavage Factor Two 1357.0 0 0 0 0 0.15223536545570895 Q06632 0.9491789937019348 0.9472420215606691 0.6622533202171326 0.011817111633718014 42.54108354368441 40.0 1.0 no 2562 chrIV_1065133r 7825 essential YDR301W 1784 - CACTTTCATATATGTCACTC S|601|T S|601|N E|600|Q E|600|K CFT1 Cleavage Factor Two 1357.0 0 0 0 0 0.008174727367221819 Q06632 0.9512869715690612 0.9536849856376648 0.956179976463318 0.9475290179252625 0.028571257367730137 0.007462752517312766 0.4765619337558746 0.686187207698822 42.43786111138973 35.0 1.0 no 2563 chrIV_1065206 7827 essential YDR301W 1854 + ACAGTTTACATTTCAATGTT T|619|R T|619|I CFT1 Cleavage Factor Two 1357.0 0 0 0 0 -0.3230250383895746 Q06632 0.9476869702339172 0.9472420215606691 0.0 0.0 39.16852831203784 25.0 1.0 no 2564 chrIV_1065599 7831 essential YDR301W 2247 + GACAGAATCTTTCAACTAAA D|750|E silent|GAC>GAT|D|750 CFT1 Cleavage Factor Two 1357.0 0 0 0 0 0.8850250059379721 Q06632 0.9532920122146606 0.9486154913902284 35.22720851129617 30.0 1.0 no 2565 chrIV_1065700 7833 essential YDR301W 2348 + ACAAGTAATGATAAACAAAC Q|784|E Q|784|* CFT1 Cleavage Factor Two 1357.0 0 0 0 0 -0.2029641248460699 Q06632 0.9590039849281312 0.4394679069519043 28.826034087783114 25.0 1.0 no 2566 chrIV_1065857 7834 essential YDR301W 2505 + CCTGACAATGCATACGCCAA P|836|R P|836|L D|837|E silent|GAC>GAT|D|837 CFT1 Cleavage Factor Two 1357.0 0 0 0 0 -0.3341849559392663 Q06632 0.9432820081710817 0.9430609941482544 0.9532920122146606 0.0 0.0 0.9154778122901917 49.08694972206519 50.0 1.0 no 2567 chrIV_1065856 7835 essential YDR301W 2504 + TCCTGACAATGCATACGCCA P|836|R P|836|L P|836|A P|836|S CFT1 Cleavage Factor Two 1357.0 0 0 0 0 0.19591688031423848 Q06632 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 51.57650663762718 50.0 1.0 no 2568 chrIV_1065873r 7836 essential YDR301W 2524 - TTCGATGGAACTAACACCCT E|848|Q E|848|K CFT1 Cleavage Factor Two 1357.0 0 0 0 0 0.32702088759238057 Q06632 0.956179976463318 0.9475290179252625 0.05835032090544701 0.2447015941143036 46.66956902269516 45.0 1.0 no 2569 chrIV_1065959r 7839 essential YDR301W 2610 - TCTTCTTTTATTAATATGTA D|877|H D|877|N E|876|Q E|876|K CFT1 Cleavage Factor Two 1357.0 0 0 0 0 -0.9415253981775632 Q06632 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.5539265275001526 0.6665096282958984 0.4342929720878601 0.6422213315963745 34.41214298064375 15.0 1.0 no 2570 chrIV_1066100 7842 essential YDR301W 2748 + ACTACTGACAATATGTACTA T|917|S T|917|I T|918|S T|918|I CFT1 Cleavage Factor Two 1357.0 0 0 0 0 0.26475956177746923 Q06632 0.9491789937019348 0.9472420215606691 0.9491789937019348 0.9472420215606691 0.9915670156478882 0.12606176733970642 0.8720753788948059 0.499323159456253 37.79291951788173 30.0 1.0 no 2571 chrIV_1066244r 7843 essential YDR301W 2895 - TCTTCTCCTAATGCTTCGTA D|972|H D|972|N E|971|Q E|971|K CFT1 Cleavage Factor Two 1357.0 0 0 0 0 -0.6011787960612437 Q06632 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.012768099084496498 0.028587851673364636 0.10938521474599837 0.11056764423847197 49.721443995583456 40.0 1.0 no 2572 chrIV_1066343r 7846 essential YDR301W 2994 - TCAATGACCTTCCAACTTTT D|1005|H D|1005|N CFT1 Cleavage Factor Two 1357.0 0 0 0 0 -0.14426163576885725 Q06632 0.9486550092697144 0.956179976463318 0.006176235619932413 0.019299032166600227 45.208418330511286 35.0 1.0 no 2573 chrIV_1066379r 7847 essential YDR301W 3030 - TCATTGACGACAGAATTCTT E|1017|Q E|1017|K CFT1 Cleavage Factor Two 1357.0 0 0 0 0 0.4424281031776767 Q06632 0.956179976463318 0.9475290179252625 0.5128864645957947 0.8016250133514404 40.80513373118498 35.0 1.0 no 2574 chrIV_1067840 7848 essential YDR302W 109 + ATCGTCCACCTGTGTATGTG R|38|G R|38|C P|39|A P|39|S 0 0 0 0 -0.06404876265427642 Q06636 0.8994590044021606 0.8926740288734436 0.9562489986419678 0.9498909711837769 0.4480426609516144 0.08980938792228699 1.0 0.8267288208007812 53.406290017378865 50.0 1.0 no 2575 chrIV_1067998 7849 essential YDR302W 267 + TTCAATAAATGCACAGTTTA F|90|L silent|TTC>TTT|F|90 0 0 0 0 -0.5110921440586347 Q06636 0.9387490153312684 0.9284325838088988 36.20798400650301 25.0 1.0 no 2576 chrIV_1069651 7853 essential YDR303C 1716 - TCAAAATCGTTGTTCAACAA E|579|Q E|579|K RSC3 Remodel the Structure of Chromatin 885.0 0 0 0 0 -0.01645765656195035 Q06639 0.410547137260437 0.5728840231895447 36.49115702123584 30.0 0.0 no 2577 chrIV_1069664 7854 essential YDR303C 1703 - TCAACAAAGGATCAATAATT L|574|F silent|TTG>TTA|L|574 L|573|F silent|TTG>TTA|L|573 RSC3 Remodel the Structure of Chromatin 885.0 0 0 0 0 -1.3172408105963498 Q06639 0.0 0.0914805456995964 32.532112168611434 25.0 0.0 no 2578 chrIV_1069663 7855 essential YDR303C 1704 - TTCAACAAAGGATCAATAAT L|574|F silent|TTG>TTA|L|574 L|573|F silent|TTG>TTA|L|573 RSC3 Remodel the Structure of Chromatin 885.0 0 0 0 0 -1.5840827986837347 Q06639 0.0 0.0914805456995964 32.532112168611434 25.0 0.0 no 2579 chrIV_1069718 7857 essential YDR303C 1649 - ACGGCAATTGACCTAAGAAA silent|CCG>CCC|P|556 silent|CCG>CCA|P|556 L|555|F silent|TTG>TTA|L|555 RSC3 Remodel the Structure of Chromatin 885.0 0 0 0 0 -0.8501771611152529 Q06639 0.0460524782538414 40.98090461001073 40.0 0.0 no 2580 chrIV_1069729r 7859 essential YDR303C 1635 + TGCTGGAGACACCTTTTCTT C|546|W silent|TGC>TGT|C|546 RSC3 Remodel the Structure of Chromatin 885.0 0 0 0 0 -0.10744782939229812 Q06639 0.0018447617767378688 51.477575670719936 45.0 0.0 no 2581 chrIV_1069773r 7860 essential YDR303C 1591 + ATCAATCTCATATTTTGACC Q|532|E Q|532|* S|533|C S|533|F RSC3 Remodel the Structure of Chromatin 885.0 0 0 0 0 0.6243164234546774 Q06639 0.8475260734558105 0.08994989842176437 0.21184159815311432 40.78217547217628 30.0 0.0 no 2582 chrIV_1070179 7865 essential YDR303C 1188 - GGCTTATTAATGGTGTTAGA K|402|N silent|AAG>AAA|K|402 RSC3 Remodel the Structure of Chromatin 885.0 0 0 0 0 -0.7926156926684007 Q06639 43.33905959529659 35.0 0.0 no 2583 chrIV_1070459 7870 essential YDR303C 908 - GTTCAATCAAATACTGAATC E|309|Q E|309|K RSC3 Remodel the Structure of Chromatin 885.0 0 0 0 0 -1.075068880822629 Q06639 0.37570005655288696 0.4225439131259918 34.75848635522374 30.0 0.0 no 2584 chrIV_1070602 7871 essential YDR303C 765 - TCCTTAAATTCATTAAGATG K|261|N silent|AAG>AAA|K|261 D|262|H D|262|N RSC3 Remodel the Structure of Chromatin 885.0 0 0 0 0 0.2934968787743745 Q06639 0.01979844085872173 0.08898350596427917 0.3299266993999481 35.001006609424216 25.0 0.0 no 2585 chrIV_1070905r 7879 essential YDR303C 459 + ACTCCACTCAATTGGGTTCA P|155|A P|155|S T|154|S T|154|I RSC3 Remodel the Structure of Chromatin 885.0 0 0 0 0 1.2129510346048091 Q06639 0.9449355602264404 0.956121563911438 0.0893622487783432 0.3375561833381653 50.93777909953985 45.0 0.0 no 2586 chrIV_1070963r 7882 essential YDR303C 401 + TCCAAAATCAGTGCCTTCCT P|135|R P|135|L P|135|A P|135|S RSC3 Remodel the Structure of Chromatin 885.0 0 0 0 0 -0.9895390487425182 Q06639 0.0 0.0 0.0 0.0 51.58359308015218 45.0 0.0 no 2587 chrIV_1071023r 7883 essential YDR303C 341 + ACTTAATAATAGATCATCTG L|115|V L|115|F RSC3 Remodel the Structure of Chromatin 885.0 0 0 0 0 -1.7778769257813902 Q06639 0.3523800075054169 0.1833573430776596 33.50609229377602 25.0 0.0 no 2588 chrIV_1071195 7887 essential YDR303C 172 - TACTTGGCGTGTATTGGAAG V|64|L V|64|I RSC3 Remodel the Structure of Chromatin 885.0 0 0 0 0 -0.5471652263557248 Q06639 0.7127929329872131 0.6006066203117371 45.35695084951078 45.0 0.0 no 2589 chrIV_1071314 7892 essential YDR303C 53 - CGCAGCCTATCTTCCTCTTA C|24|S C|24|Y G|23|A G|23|D RSC3 Remodel the Structure of Chromatin 885.0 0 0 0 0 -4.119581106535456 Q06639 0.0 0.0 0.0 0.0 56.60032067188928 50.0 0.0 yes 2590 chrIV_1078205r 7899 essential YDR308C 222 + AAGCTTATTGACTCGTTACC L|76|V L|76|F SRB7 Suppressor of RNA polymerase B 140.0 0 0 0 0 0.5161256606225834 P47822 0.9417229890823364 0.9538249969482422 0.030779654160141945 0.0219047237187624 0.7081999778747559 1.7809400558471682 45.400201281053675 40.0 0.0 no 2591 chrIV_1078257r 7900 essential YDR308C 170 + CACGATAGATGAGCTATCCA T|58|R T|58|M SRB7 Suppressor of RNA polymerase B 140.0 0 0 0 0 0.11103847545110496 P47822 0.929751992225647 0.93230402469635 0.5409209132194519 0.1154145449399948 46.39746350044806 45.0 0.0 no 2592 chrIV_1078300 7902 essential YDR308C 130 - TACTACTGTGGCATGCTTAT V|50|L V|50|I V|49|L V|49|I SRB7 Suppressor of RNA polymerase B 140.0 0 0 0 0 -0.4569346625840661 P47822 0.9558470249176024 0.9592949748039246 0.9558470249176024 0.9592949748039246 0.3067775368690491 0.1897432953119278 0.3531173765659332 0.4795298576354981 -1.1110600233078003 -0.319379985332489 -0.6004999876022339 -0.2448199987411499 47.809425481592996 40.0 0.0 no 2593 chrIV_1078389 7906 essential YDR308C 41 - CACAGAATTGCTCCGTCATT C|20|S C|20|Y SRB7 Suppressor of RNA polymerase B 140.0 0 0 0 0 0.6335330489520042 P47822 0.9446370005607604 0.9329959750175476 0.3947692513465881 1.0 -0.07637999951839447 -1.1918599605560305 -0.20371000468730927 -1.50764000415802 48.780641429182886 45.0 0.0 no 2594 chrIV_1085083 7907 essential YDR311W 18 + GCCATTTTTGAGAAAGTTTC silent|GCC>GCG|A|7 silent|GCC>GCT|A|7 A|7|G A|7|V TFB1 Transcription Factor B 642.0 0 0 0 0 0.3372705014585585 P32776 0.9484469890594482 0.9504740238189696 0.0 0.0 -1.4177600145339966 8.436739921569824 -2.0226399898529053 9.615360260009766 42.57384171526485 35.0 1.0 no 2595 chrIV_1085135r 7910 essential YDR311W 73 - AGACCTCCATGTCAATTCTG R|30|S silent|AGG>AGA|R|30 R|30|T R|30|K TFB1 Transcription Factor B 642.0 0 0 0 0 0.543164708757753 P32776 0.9087679982185364 0.932735025882721 0.955805003643036 0.26432693004608154 0.07803625613451004 0.9169238209724426 1.3393800258636477 0.8173999786376953 -0.14880000054836273 49.133183327867066 45.0 1.0 no 2596 chrIV_1085192r 7911 essential YDR311W 130 - AGCTTGTAACTTGTCAATAG A|50|P A|50|T TFB1 Transcription Factor B 642.0 0 0 0 0 0.4432532148849557 P32776 0.9573720097541808 0.9523990154266356 0.0 0.0 1.1970000267028809 0.8241400122642517 1.136199951171875 0.2289399951696396 40.6562551070686 35.0 1.0 no 2597 chrIV_1085308r 7912 essential YDR311W 246 - AACATATGACGTTGCGGTTT M|88|I M|88|I TFB1 Transcription Factor B 642.0 0 0 0 0 0.2520573500535988 P32776 0.9553959965705872 0.9553959965705872 0.3731800317764282 0.3731800317764282 0.1599999964237213 0.1599999964237213 -0.1816200017929077 -0.1816200017929077 44.869107199567175 40.0 1.0 no 2598 chrIV_1085468 7915 essential YDR311W 403 + GCTCTTCTTCTGTTACTGCA S|136|C S|136|F S|135|R silent|AGC>AGT|S|135 TFB1 Transcription Factor B 642.0 0 0 0 0 0.8417356379775287 P32776 0.945252001285553 0.9294660091400146 0.9417110085487366 0.024349436163902283 0.015555577352643013 0.3008333444595337 54.04770728315867 45.0 1.0 no 2599 chrIV_1085510 7916 essential YDR311W 445 + ATACACCACAATTGAATAAT T|150|R T|150|I P|151|A P|151|S TFB1 Transcription Factor B 642.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.12211123734037392 P32776 0.9476869702339172 0.9472420215606691 0.9562489986419678 0.9498909711837769 0.6666080355644226 0.18790727853775024 0.966475248336792 1.0 35.166037621269986 25.0 1.0 no 2600 chrIV_1085697 7917 essential YDR311W 632 + AACTAGAATTCCGTTATTGA T|212|S T|212|I TFB1 Transcription Factor B 642.0 0 0 0 0 0.5664810432221934 P32776 0.9491789937019348 0.9472420215606691 0.2358389347791672 0.008787820115685463 39.44069751213493 30.0 1.0 no 2601 chrIV_1085772 7919 essential YDR311W 707 + TATCAAGCCGGTGGCTTCAT I|237|M silent|ATC>ATT|I|237 TFB1 Transcription Factor B 642.0 0 0 0 0 -0.4495191680717432 P32776 0.9598389863967896 0.0 53.45290301012949 50.0 1.0 no 2602 chrIV_1086267 7928 essential YDR311W 1202 + ATCTAATATTACAAACGATG S|402|C S|402|F TFB1 Transcription Factor B 642.0 0 0 0 0 0.3699564514277921 P32776 0.945252001285553 0.9294660091400146 32.00760853148688 25.0 1.0 no 2603 chrIV_1112847 7932 high_effect YDR323C 1161 - TGTCTCTCTAGATGACTTTG R|393|T R|393|K E|392|D silent|GAG>GAA|E|392 PEP7 carboxyPEPtidase Y-deficient 515.0 0 0 0 0 -1.1091876650090842 P32609 0.932735025882721 0.955805003643036 0.94931298494339 0.4873028993606568 1.0 0.0 44.88170850731053 40.0 0.0 no 2604 chrIV_1112986 7933 high_effect YDR323C 1022 - CCTTGGCAGTCTCCACCTTC K|347|N silent|AAG>AAA|K|347 A|346|P A|346|T PEP7 carboxyPEPtidase Y-deficient 515.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.9866060736016192 P32609 0.9355990290641784 0.9573720097541808 0.9523990154266356 0.13007083535194394 0.2827363908290863 0.5948053002357483 62.09152285348985 60.0 0.0 no 2605 chrIV_1113201 7942 high_effect YDR323C 807 - TTCTGTATATTGTATTCGAA Q|275|H silent|CAG>CAA|Q|275 PEP7 carboxyPEPtidase Y-deficient 515.0 0 0 0 0 -0.6710647717803326 P32609 0.9570760130882264 0.12153930962085725 37.98922280594189 25.0 0.0 no 2606 chrIV_1113341r 7943 high_effect YDR323C 664 + ACATATGTTCCGAACCATTT N|222|K silent|AAC>AAT|N|222 PEP7 carboxyPEPtidase Y-deficient 515.0 0 0 0 0 -0.21297746409038432 P32609 0.9439849853515624 0.2977010607719421 45.03744747377863 35.0 0.0 no 2607 chrIV_1113342r 7944 high_effect YDR323C 663 + AACATATGTTCCGAACCATT N|222|K silent|AAC>AAT|N|222 PEP7 carboxyPEPtidase Y-deficient 515.0 0 0 0 0 -0.6492894013533741 P32609 0.9439849853515624 0.2977010607719421 43.40056042629681 35.0 0.0 no 2608 chrIV_1113375 7945 high_effect YDR323C 633 - ACACTTCTATCATCTCTCCA S|217|T S|217|N V|218|L V|218|I PEP7 carboxyPEPtidase Y-deficient 515.0 0 0 0 0 0.35770176677326765 P32609 0.9512869715690612 0.9536849856376648 0.9539830088615416 0.9574310183525084 0.6031613945960999 0.5320104360580444 0.08022589236497879 0.11437040567398073 50.159840840987044 40.0 0.0 no 2609 chrIV_1113597 7947 high_effect YDR323C 411 - TCGCCATAATCGTTATAGCC G|143|A G|143|D E|144|Q E|144|K PEP7 carboxyPEPtidase Y-deficient 515.0 0 0 0 0 -0.8972396146060991 P32609 0.9499930143356324 0.9446240067481996 0.956179976463318 0.9475290179252625 0.0 0.0 0.5357815027236938 0.7743799090385437 49.320372464646255 45.0 0.0 no 2610 chrIV_1113600r 7948 high_effect YDR323C 405 + AAACCTGGCTATAACGATTA P|137|A P|137|S P|137|R P|137|L PEP7 carboxyPEPtidase Y-deficient 515.0 0 0 0 0 -0.2710726831058121 P32609 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.0 0.0 0.0 0.0 40.57981688880545 35.0 0.0 no 2611 chrIV_1113734 7949 high_effect YDR323C 274 - ACCACATTTCCTACAATTAA G|98|R G|98|S G|98|A G|98|D PEP7 carboxyPEPtidase Y-deficient 515.0 0 0 0 0 -0.7045867427967961 P32609 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 41.81516111691252 30.0 0.0 no 2612 chrIV_1113938r 7954 high_effect YDR323C 67 + CACATTTAGATGTTGAGCAT H|24|D H|24|Y PEP7 carboxyPEPtidase Y-deficient 515.0 0 0 0 0 0.1476038310115682 P32609 0.9473130106925964 0.9489949941635132 0.0 0.0 42.477074190971216 35.0 0.0 no 2613 chrIV_1113980 7957 high_effect YDR323C 28 - ATCAAACTTCCTTAGACAAA D|16|H D|16|N K|14|N silent|AAG>AAA|K|14 PEP7 carboxyPEPtidase Y-deficient 515.0 0 0 0 0 0.5149354186077697 P32609 0.9486550092697144 0.956179976463318 0.9355990290641784 0.1668734848499298 0.5164920687675476 0.5173729658126831 37.8363531045809 30.0 0.0 no 2614 chrIV_1115121r 7959 essential YDR324C 1620 + GCAGTAATTTCTCGTGGCTG A|541|G A|541|V UTP4 U Three Protein 776.0 0 0 0 0 0.6709882999907365 Q06679 0.9484469890594482 0.9504740238189696 0.0058664595708251 0.38363462686538696 50.8249607165003 50.0 0.0 no 2615 chrIV_1115174r 7960 essential YDR324C 1567 + TCAAAGTTCCCTATATTAAC I|523|M silent|ATC>ATT|I|523 UTP4 U Three Protein 776.0 0 0 0 0 1.0507829853005275 Q06679 0.9598389863967896 0.2522986233234405 39.52489277165239 30.0 0.0 no 2616 chrIV_1115378 7964 essential YDR324C 1366 - CACTTTCAATTTATTACCTA V|462|L V|462|M L|460|F silent|TTG>TTA|L|460 UTP4 U Three Protein 776.0 0 0 0 0 -0.05834638593988588 Q06679 0.9539830088615416 0.9587630033493042 0.9587849974632264 0.11773772537708282 0.027474287897348404 0.282429963350296 39.40765717568411 25.0 0.0 no 2617 chrIV_1115379 7965 essential YDR324C 1365 - ACTTTCAATTTATTACCTAC V|462|L V|462|M L|460|F silent|TTG>TTA|L|460 UTP4 U Three Protein 776.0 0 0 0 0 -0.13354327197502416 Q06679 0.9539830088615416 0.9587630033493042 0.9587849974632264 0.11773772537708282 0.027474287897348404 0.282429963350296 38.47687940010161 25.0 0.0 no 2618 chrIV_1115439 7967 essential YDR324C 1305 - ACGACTAAAACTTGTCCATC V|442|L V|442|I V|441|L V|441|I UTP4 U Three Protein 776.0 0 0 0 0 0.2607608465356768 Q06679 0.9539830088615416 0.9574310183525084 0.9539830088615416 0.9574310183525084 0.0 0.0 0.4447465837001801 0.684183657169342 41.645191185872534 40.0 0.0 no 2619 chrIV_1115525 7968 essential YDR324C 1219 - ATTCTGTTCTGTACTAGAAT Q|412|H silent|CAG>CAA|Q|412 UTP4 U Three Protein 776.0 0 0 0 0 0.20840929092795327 Q06679 0.9570760130882264 0.11099900305271147 41.04821440616973 30.0 0.0 no 2620 chrIV_1115454r 7969 essential YDR324C 1287 + ACTTGTTCTTTATCACCTGA T|430|S T|430|I UTP4 U Three Protein 776.0 0 0 0 0 0.6613649542838316 Q06679 0.9491789937019348 0.9472420215606691 1.0 0.06614011526107788 47.02869427684965 35.0 0.0 no 2621 chrIV_1115550r 7971 essential YDR324C 1191 + ACTGTTAAGATATGGACAAT T|398|S T|398|I UTP4 U Three Protein 776.0 0 1 0 0 0.4572274174323773 Q06679 0.9491789937019348 0.9472420215606691 0.19440224766731265 0.01174746360629797 36.94108020083314 30.0 0.0 no 2622 chrIV_1115613 7975 essential YDR324C 1131 - ACTAAAACATTCTTTGAATA V|384|L V|384|I UTP4 U Three Protein 776.0 0 0 0 0 0.5069378987862051 Q06679 0.9539830088615416 0.9574310183525084 0.11585482954978946 0.3509313762187958 31.81453048883543 20.0 0.0 no 2623 chrIV_1115932r 7980 essential YDR324C 809 + CACGCTAAACCAGTCATTTA T|271|R T|271|M L|272|V silent|CTA>TTA|L|272 UTP4 U Three Protein 776.0 0 0 0 0 -0.13088319418476976 Q06679 0.9476869702339172 0.9502379894256592 0.9512209892272948 0.017049668356776237 0.012253751046955584 0.019762279465794563 44.5421268985711 40.0 0.0 no 2624 chrIV_1116073r 7981 essential YDR324C 668 + TCGTCTATTACACACTATGA R|224|G R|224|C L|225|V silent|CTA>TTA|L|225 UTP4 U Three Protein 776.0 0 0 0 0 -0.3164940714160951 Q06679 0.8994590044021606 0.8926740288734436 0.9512209892272948 0.015815651044249538 0.0021878795232623816 0.11458908766508102 42.333894125545896 35.0 0.0 no 2625 chrIV_1116245r 7987 essential YDR324C 496 + TCCTCATAGATATCTCTGGC L|167|V L|167|F silent|GTC>GTG|V|166 silent|GTC>GTT|V|166 UTP4 U Three Protein 776.0 0 1 0 0 -1.1011362334131582 Q06679 0.9512209892272948 0.9587849974632264 1.0 0.019322669133543968 50.382438674802245 45.0 0.0 no 2626 chrIV_1116288r 7989 essential YDR324C 453 + TCACAAGACAAGCTGTCTGT Q|153|E Q|153|* S|152|* S|152|L UTP4 U Three Protein 776.0 0 1 0 0 0.02829705137273092 Q06679 0.9590039849281312 0.9298099875450134 0.6738371253013611 0.17983773350715634 46.70886960168855 45.0 0.0 no 2627 chrIV_1116345 7990 essential YDR324C 399 - TTGCAATCATAGTTTCTTAA C|139|S C|139|Y UTP4 U Three Protein 776.0 0 0 0 0 -0.2190175821353104 Q06679 0.9421560168266296 0.9290120005607604 0.03308376297354698 0.002887862734496593 38.63186123849732 25.0 0.0 no 2628 chrIV_1116411r 7995 essential YDR324C 330 + TCTCTAAGGCTATTTTCTAT L|112|V silent|CTA>TTA|L|112 S|111|C S|111|F UTP4 U Three Protein 776.0 0 0 0 0 -1.6826563939174144 Q06679 0.9512209892272948 0.945252001285553 0.9294660091400146 0.6345824003219604 0.04653852805495262 0.04624414071440697 43.05741985517909 30.0 0.0 no 2629 chrIV_1116554 8001 essential YDR324C 190 - ACCAATAGCTAATCTCAAAT G|70|R G|70|S G|70|A G|70|D UTP4 U Three Protein 776.0 0 0 0 0 -0.7719706038395474 Q06679 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0054925219155848035 0.03527546674013138 0.14906172454357147 0.008338719606399536 38.68317120457994 30.0 0.0 no 2630 chrIV_1116665 8005 essential YDR324C 79 - CACTATCATCCTTTCCTGAC V|33|L V|33|M M|31|I M|31|I UTP4 U Three Protein 776.0 0 0 0 0 -0.6600622317042643 Q06679 0.9539830088615416 0.9587630033493042 0.9553959965705872 0.9553959965705872 0.05556310713291168 0.010256954468786716 0.08523046970367433 0.08523046970367433 50.10558755249849 45.0 0.0 no 2631 chrIV_1116678 8006 essential YDR324C 66 - TCCTGACTGGTCATCTTCAC Q|28|H silent|CAG>CAA|Q|28 E|29|Q E|29|K UTP4 U Three Protein 776.0 0 0 0 0 -4.672514394686513 Q06679 0.9570760130882264 0.956179976463318 0.9475290179252625 52.933744921379116 50.0 0.0 yes 2632 chrIV_1117320r 8008 essential YDR325W 197 - TCTCATTCTTTTTCAGAGGA E|72|Q E|72|K E|72|D silent|GAG>GAA|E|72 YCG1 Yeast Cap G 1035.0 0 0 0 0 1.331917907415992 Q06680 0.956179976463318 0.9475290179252625 0.94931298494339 0.04329317435622215 0.035714220255613334 0.20552800595760345 45.778596901759435 35.0 1.0 no 2633 chrIV_1117477 8009 essential YDR325W 351 + TTCATAAGACATGTTTTGCG F|118|L silent|TTC>TTT|F|118 YCG1 Yeast Cap G 1035.0 0 0 0 0 0.9250580962071844 Q06680 0.9387490153312684 0.8720378279685974 40.98431068044664 35.0 1.0 no 2634 chrIV_1117639r 8013 essential YDR325W 516 - ACAGCCTGTATCCTAACCGT V|179|L V|179|M A|178|P A|178|T YCG1 Yeast Cap G 1035.0 0 0 0 0 -3.624618619713223 Q06680 0.9539830088615416 0.9587630033493042 0.9573720097541808 0.9523990154266356 0.4207168221473694 0.022302670404315 0.0 0.0 54.52113928737879 50.0 1.0 yes 2635 chrIV_1117776 8016 essential YDR325W 650 + TCCGTCAGCTGAAGTACGGA P|218|R P|218|L P|218|A P|218|S YCG1 Yeast Cap G 1035.0 0 0 0 0 -2.550871365956741 Q06680 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.05436960980296135 0.038494031876325614 0.13113895058631894 0.348349928855896 52.410719878532745 55.00000000000001 1.0 yes 2636 chrIV_1118025 8019 essential YDR325W 899 + TCATGATTGGTTAAATGCTC H|301|D H|301|Y YCG1 Yeast Cap G 1035.0 0 0 0 0 -0.8670859413445909 Q06680 0.9473130106925964 0.9489949941635132 0.24334540963172915 1.0 40.98011505318016 35.0 1.0 no 2637 chrIV_1118408r 8025 essential YDR325W 1285 - GCTATAATCATACCTTTCGG S|435|T S|435|N YCG1 Yeast Cap G 1035.0 0 0 0 0 -0.2600735386328761 Q06680 0.9512869715690612 0.9536849856376648 0.0 0.0 45.02899435325139 40.0 1.0 no 2638 chrIV_1118411r 8026 essential YDR325W 1288 - ATCGCTATAATCATACCTTT D|436|H D|436|N S|435|T S|435|N YCG1 Yeast Cap G 1035.0 0 0 0 0 0.7118424262339421 Q06680 0.9486550092697144 0.956179976463318 0.9512869715690612 0.9536849856376648 0.02970861829817295 0.13195981085300446 0.0 0.0 42.70664970192678 30.0 1.0 no 2639 chrIV_1118494 8028 essential YDR325W 1368 + TCCGAACCTCTTATTAAAAT silent|TCC>TCG|S|457 silent|TCC>TCT|S|457 S|457|C S|457|F YCG1 Yeast Cap G 1035.0 0 0 0 0 0.07059089277661472 Q06680 0.945252001285553 0.9294660091400146 0.047829851508140564 0.028155907988548282 39.39101313648911 30.0 1.0 no 2640 chrIV_1118934 8036 essential YDR325W 1808 + GGACACTTTGATCACACCAG D|604|E silent|GAC>GAT|D|604 T|605|S T|605|I YCG1 Yeast Cap G 1035.0 0 0 0 0 -1.6871461247681312 Q06680 0.9532920122146606 0.9491789937019348 0.9472420215606691 0.2381448298692703 0.398747444152832 0.00822004396468401 48.275644185368826 50.0 1.0 no 2641 chrIV_1118971r 8038 essential YDR325W 1848 - ACACCAAGCTCCCTAATATT G|622|A G|622|D V|623|L V|623|I YCG1 Yeast Cap G 1035.0 0 0 0 0 -2.1795554225012816 Q06680 0.9499930143356324 0.9446240067481996 0.9539830088615416 0.9574310183525084 0.0 0.0 0.4191620647907257 0.7139620184898376 48.453424665643404 40.0 1.0 yes 2642 chrIV_1119223r 8044 essential YDR325W 2100 - GCTGCTATCACCTGACATTC A|707|P A|707|T A|706|P A|706|T YCG1 Yeast Cap G 1035.0 0 0 0 0 -0.11977415810954672 Q06680 0.9573720097541808 0.9523990154266356 0.9573720097541808 0.9523990154266356 0.022785311564803123 0.016229430213570598 0.08806725591421127 0.4526152908802033 52.46607902170706 50.0 1.0 no 2643 chrIV_1119368r 8047 essential YDR325W 2245 - ACAATAGACTGGAATGCAGA C|755|S C|755|Y YCG1 Yeast Cap G 1035.0 0 0 0 0 -0.7645025635657996 Q06680 0.9421560168266296 0.9290120005607604 0.05407893657684326 0.004368783440440893 40.89525339548123 40.0 1.0 no 2644 chrIV_1119408 8050 essential YDR325W 2282 + TCAACAACGTATGTCTAGGA Q|762|E Q|762|* Q|763|E Q|763|* YCG1 Yeast Cap G 1035.0 0 0 0 0 -0.4664012944752599 Q06680 0.9590039849281312 0.9590039849281312 0.0 1.0 42.36240384884872 40.0 1.0 no 2645 chrIV_1125654 8058 essential YDR328C 345 - TCTCTGTCCCATGAGTCCAC R|121|T R|121|K E|122|Q E|122|K SKP1 Suppressor of Kinetochore Protein mutant 194.0 0 0 0 0 0.16724961846196296 P52286 0.574602484703064 0.9487013816833496 0.19693489372730252 0.6929065585136414 0.19708000123500824 -0.4122200012207031 -0.09860000014305116 -0.03562000021338463 58.51135234892786 55.00000000000001 0.0 no 2646 chrIV_1125743 8059 essential YDR328C 256 - TTCGATAACCTTCTGCAAAA E|92|Q E|92|K SKP1 Suppressor of Kinetochore Protein mutant 194.0 0 0 0 0 0.7954132481240742 P52286 0.5171075463294983 0.1412399858236313 -0.5091000199317932 -0.369599997997284 40.82552920267398 35.0 0.0 no 2647 chrIV_1125976 8061 essential YDR328C 23 - GTTCACCCTCACCACTCACT E|14|Q E|14|K G|13|A G|13|D SKP1 Suppressor of Kinetochore Protein mutant 194.0 0 0 0 0 -1.385238344388278 P52286 0.15729795396327972 0.3722975254058838 0.026659952476620674 0.2973300516605377 0.1525000035762787 -0.37553998827934265 2.9813001155853267 2.8844199180603027 59.18402904375 55.00000000000001 0.0 no 2648 chrIV_1129706 8064 essential YDR331W 118 + CCGTATTAGTATCCACGTCG silent|GCC>GCG|A|40 silent|GCC>GCT|A|40 0 0 0 0 0.5838300994430982 P49018 50.22382372817082 50.0 1.0 no 2649 chrIV_1129761r 8066 essential YDR331W 176 - TTACAGTCCTATACATACTA V|65|L V|65|I 0 0 0 0 0.9281847466529052 P49018 0.9539830088615416 0.9574310183525084 0.03410358354449272 0.1332448273897171 41.64304045332409 30.0 1.0 no 2650 chrIV_1129885 8067 essential YDR331W 297 + GATCACGCTATTGACCTTTA H|101|D H|101|Y H|101|Q silent|CAC>CAT|H|101 0 0 0 0 0.2672615658538475 P49018 0.9473130106925964 0.9489949941635132 0.9588389992713928 0.1437392234802246 0.0834951177239418 0.4430336058139801 0.6647999882698059 0.3192000091075897 -0.024000000208616257 46.80874649865665 40.0 1.0 no 2651 chrIV_1130215 8076 essential YDR331W 627 + TCTCCAAATATTCTGGCTGT P|211|A P|211|S S|210|C S|210|F 0 0 0 0 -0.5638219049710893 P49018 0.9562489986419678 0.9498909711837769 0.945252001285553 0.9294660091400146 0.009259309619665146 0.007642553187906742 0.0014596014516428113 0.0006690529990009964 48.048291848673784 40.0 1.0 no 2652 chrIV_1130082r 8077 essential YDR331W 497 - AAGCAATCTCTTCAGCATCT A|172|P A|172|T 0 0 0 0 0.10597912255640644 P49018 0.9573720097541808 0.9523990154266356 0.1814887821674347 0.944448947906494 -0.436599999666214 0.8672000169754028 47.30707600732569 40.0 1.0 no 2653 chrIV_1130449r 8083 essential YDR331W 864 - TCAGTAATCAATACTTCTGA D|295|H D|295|N 0 0 0 0 0.21738243283384764 P49018 0.9486550092697144 0.956179976463318 0.002702056895941496 0.09303044527769087 38.642562465697715 30.0 1.0 no 2654 chrIV_1150132 8087 essential YDR339C 369 - CAGCTTAGTCTCTTTATTCT S|129|T S|129|N FCF1 Faf1p Copurifying Factor 189.0 0 0 0 0 -0.034672205136981486 Q05498 0.9512869715690612 0.9536849856376648 0.5811094641685486 0.19574087858200076 47.3082880486245 35.0 0.0 no 2655 chrIV_1150168 8090 essential YDR339C 333 - TTCAAGGCGATACGGTACTT L|117|F silent|TTG>TTA|L|117 FCF1 Faf1p Copurifying Factor 189.0 0 0 0 0 -0.8647844003875075 Q05498 0.9587849974632264 0.004026308190077543 46.7270552036964 45.0 0.0 no 2656 chrIV_1150213 8092 essential YDR339C 288 - ATCACACAATCTGTGATTAA silent|GTG>GTC|V|102 silent|GTG>GTA|V|102 V|102|L V|102|M FCF1 Faf1p Copurifying Factor 189.0 0 0 0 0 0.5819890998487898 Q05498 0.9539830088615416 0.9587630033493042 0.012865089811384678 0.003917350433766842 38.31942646712975 30.0 0.0 no 2657 chrIV_1152256 8097 essential YDR341C 1351 - GGCAGAGATACCAACTAAAT A|457|P A|457|T 607.0 0 0 0 0 -2.8827590257721214 Q05506 0.9573720097541808 0.9523990154266356 0.013043474406003952 0.009331390261650084 9.171339988708496 2.796380043029785 41.53646896875893 40.0 0.0 yes 2658 chrIV_1152357r 8098 essential YDR341C 1247 + CTTCTTAGATAATATCTTGG F|417|L silent|TTC>TTT|F|417 607.0 0 0 0 0 0.7827727790493403 Q05506 0.9387490153312684 0.19624090194702148 0.3894599974155426 37.701659424146726 30.0 0.0 no 2659 chrIV_1152360r 8099 essential YDR341C 1244 + TGTCTTCTTAGATAATATCT silent|GTC>GTG|V|416 silent|GTC>GTT|V|416 F|417|L silent|TTC>TTT|F|417 607.0 0 0 0 0 -0.07143654305230572 Q05506 0.9387490153312684 0.19624090194702148 0.3894599974155426 38.33271123048803 25.0 0.0 no 2660 chrIV_1152419r 8102 essential YDR341C 1185 + GATCTACAGCATGTCAACTT L|397|V silent|CTA>TTA|L|397 Q|398|E Q|398|* 607.0 0 0 0 0 -0.07843095330718469 Q05506 0.9512209892272948 0.9590039849281312 0.2671650946140289 0.3961036503314972 2.5848000049591064 0.20136000216007235 45.306629860156924 40.0 0.0 no 2661 chrIV_1152459r 8106 essential YDR341C 1145 + CTTCGAAATTTTGAAGCAGA F|383|L silent|TTC>TTT|F|383 607.0 0 0 0 0 0.08552163771941063 Q05506 0.9387490153312684 0.07149457186460495 1.3459800481796265 38.854663690553885 35.0 0.0 no 2662 chrIV_1152690r 8110 essential YDR341C 914 + TATCGACCTGTTCAAGGAAA I|306|M silent|ATC>ATT|I|306 D|307|E silent|GAC>GAT|D|307 607.0 0 0 0 0 0.343038349698764 Q05506 0.9598389863967896 0.9532920122146606 0.27329498529434204 0.7208873629570007 -0.6173200011253357 -0.5787000060081482 42.53070151908997 40.0 0.0 no 2663 chrIV_1152877 8113 essential YDR341C 730 - TTCACGAGCTTTTCCATTGG E|250|Q E|250|K R|249|P R|249|H 607.0 0 0 0 0 -0.4424390252724385 Q05506 0.956179976463318 0.9475290179252625 0.9099509716033936 0.9570810198783876 0.5730739831924438 0.8858781456947327 0.0067509799264371395 0.00753709953278303 0.012600000016391277 0.1956399977207184 2.2775800228118896 0.8659399747848511 49.74945864089398 45.0 0.0 no 2664 chrIV_1152890r 8114 essential YDR341C 714 + CCATTAGAACAATCCACCAA P|239|R P|239|L 607.0 0 1 0 0 0.5022183717530084 Q05506 0.9432820081710817 0.9430609941482544 0.3711741268634796 0.21390703320503235 2.1359798908233643 1.3379000425338743 44.321608416873744 40.0 0.0 no 2665 chrIV_1152948 8116 essential YDR341C 659 - TACGAACGTAAACATCGAAC R|226|P R|226|H V|225|L V|225|I 607.0 0 1 0 0 1.4038887421441757 Q05506 0.9099509716033936 0.9570810198783876 0.9539830088615416 0.9574310183525084 0.012690852396190166 0.013955626636743546 0.061021629720926285 0.026876352727413174 4.520899772644043 0.3980399966239929 -1.354040026664734 -0.9647200107574464 36.30841204957767 40.0 0.0 no 2666 chrIV_1153087 8120 essential YDR341C 520 - ACCTAATTTTTCATAAAGGT G|180|R G|180|S G|180|A G|180|D 607.0 0 0 0 0 0.4252487696454596 Q05506 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0021344339475035667 0.05069931223988533 0.021745827049016956 0.00531168794259429 12.822279930114744 7.661280155181885 3.691400051116944 15.53514003753662 38.19489093708279 25.0 0.0 no 2667 chrIV_1153110r 8122 essential YDR341C 494 + CACTATTATTGGTGGCTTTT T|166|S T|166|I 607.0 0 0 0 0 1.4725021187042795 Q05506 0.9491789937019348 0.9472420215606691 0.0 0.0 1.6721800565719604 -1.386639952659607 45.81775893445461 35.0 0.0 no 2668 chrIV_1153232 8124 essential YDR341C 375 - TCCTTTCTGGTTAAGATATC K|131|N silent|AAG>AAA|K|131 E|132|Q E|132|K 607.0 0 0 0 0 -2.2565899299295284 Q05506 0.9355990290641784 0.956179976463318 0.9475290179252625 0.4136877655982971 0.5486805438995361 0.8709034919738771 1.622499942779541 0.9167600274086 0.4260799884796143 43.9606679480981 35.0 0.0 yes 2669 chrIV_1153233r 8126 essential YDR341C 371 + CCCAGATATCTTAACCAGAA P|125|R P|125|L P|125|A P|125|S 607.0 0 0 0 0 -0.02557823035598367 Q05506 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.2742576599121094 0.1601673662662506 0.3950711488723755 0.6982454061508179 1.7587000131607056 3.821540117263794 3.2002999782562256 3.799360036849976 45.228825152759846 40.0 0.0 no 2670 chrIV_1153385 8130 essential YDR341C 222 - GCACCTTTGATTCTCAATCT G|80|A G|80|D A|81|P A|81|T 607.0 0 0 0 0 0.6646163609107889 Q05506 0.9499930143356324 0.9446240067481996 0.9573720097541808 0.9523990154266356 0.03250560536980629 0.02654882147908211 0.1169656664133072 0.20581816136837008 1.7488000392913818 1.2572799921035769 5.97376012802124 0.5098599791526794 48.74142666471682 40.0 0.0 no 2671 chrIV_1153566r 8134 essential YDR341C 38 + ACTATCTATCGCGGAACCTG L|14|V silent|CTA>TTA|L|14 S|15|C S|15|F 607.0 0 1 0 0 -0.09296018986867803 Q05506 0.9512209892272948 0.945252001285553 0.9294660091400146 0.5381268858909607 0.11816295981407166 0.22326841950416565 1.3214800357818604 -0.24408000707626346 -0.054200001060962684 48.19106349329058 50.0 0.0 no 2672 chrIV_1183305 8135 essential YDR353W 6 + CACAACAAAGTTACTATCAT H|3|Q silent|CAC>CAT|H|3 N|4|K silent|AAC>AAT|N|4 TRR1 ThioRedoxin Reductase 319.0 0 0 0 0 -0.3083125892226258 P29509 0.26309192180633545 0.9085159897804259 0.3769200146198273 2.1908600330352783 0.20960000157356265 36.197117190420606 30.0 1.0 no 2673 chrIV_1183377 8138 essential YDR353W 78 + ATCAAGCCAATCCTATATGA I|27|M silent|ATC>ATT|I|27 P|29|A P|29|S TRR1 ThioRedoxin Reductase 319.0 0 0 0 0 0.2601415317261717 P29509 0.0653703436255455 0.0 0.0 -0.6220600008964539 2.5228800773620605 4.7083401679992685 -0.4933399856090546 44.09895733230462 35.0 1.0 no 2674 chrIV_1183383r 8139 essential YDR353W 87 - ATCATACCTTCATATAGGAT M|35|I M|35|I G|34|A G|34|D TRR1 ThioRedoxin Reductase 319.0 0 0 0 0 1.3856701543642516 P29509 0.1256486475467682 0.1256486475467682 0.0 0.0 0.8864399790763855 0.8864399790763855 4.2017998695373535 8.17411994934082 0.4670400023460388 0.4670400023460388 42.12984107444436 30.0 1.0 no 2675 chrIV_1183388r 8141 essential YDR353W 92 - TCGCCATCATACCTTCATAT A|37|P A|37|T silent|GCG>GCC|A|37 silent|GCG>GCA|A|37 TRR1 ThioRedoxin Reductase 319.0 0 0 0 0 -1.7115783702522869 P29509 0.0702543780207634 0.2581830620765686 -1.2446399927139282 0.3912000060081482 -1.2735400199890137 0.3307600021362305 49.93285726039153 40.0 1.0 no 2676 chrIV_1183458 8145 essential YDR353W 159 + AACTTCCCAGGTTTCCCAGA N|54|K silent|AAC>AAT|N|54 F|55|L silent|TTC>TTT|F|55 TRR1 ThioRedoxin Reductase 319.0 0 0 0 0 -2.5067444290526324 P29509 0.0 0.007431563921272755 -0.3518199920654297 1.5211399793624878 1.2646199464797974 2.780466794967652 6.072713375091553 56.76584936488832 50.0 1.0 yes 2677 chrIV_1183472r 8147 essential YDR353W 176 - CGCTACCTGTTAGACCATCT S|65|T S|65|N G|64|A G|64|D TRR1 ThioRedoxin Reductase 319.0 0 0 0 0 0.3270658373734726 P29509 0.09046982228755952 0.010381105355918407 0.0 0.0 0.07292000204324722 0.009100000374019146 4.5441999435424805 19.067800521850586 53.22790067802964 50.0 1.0 no 2678 chrIV_1183628 8151 essential YDR353W 329 + GACGACTGACGCTATAATCT T|111|R T|111|M T|112|S T|112|I TRR1 ThioRedoxin Reductase 319.0 0 0 0 0 -1.2502923357760116 P29509 0.5495026707649231 0.1041094809770584 0.12047800421714785 0.006153812631964684 -1.1387799978256226 -1.4764599800109863 -0.10465999692678453 3.1847798824310303 44.13914800250797 45.0 1.0 no 2679 chrIV_1183664 8153 essential YDR353W 365 + TGCTAAGAGAATGCATTTGC A|123|G A|123|V TRR1 ThioRedoxin Reductase 319.0 0 1 0 0 -0.32409747096305197 P29509 0.014617400243878363 0.04355488717556 0.7282999753952026 -0.1806199997663498 0.8103600144386292 0.21512000262737274 42.77960552613831 40.0 1.0 no 2680 chrIV_1183761 8157 essential YDR353W 462 + AAGCCATTGGCCGTCATTGG P|156|A P|156|S P|156|R P|156|L TRR1 ThioRedoxin Reductase 319.0 0 0 0 0 0.25063702205012023 P29509 0.1985401064157486 0.14509297907352448 0.09748239070177077 0.06204065307974816 1.38510000705719 1.7637200355529783 1.2590999603271484 0.6978800296783447 54.88452194491481 55.00000000000001 1.0 no 2681 chrIV_1183764r 8160 essential YDR353W 468 - CCACCACCAATGACGGCCAA G|162|A G|162|D G|163|R G|163|S TRR1 ThioRedoxin Reductase 319.0 0 0 0 0 -4.310018889984603 P29509 0.0 0.0 0.0 0.0 -0.6672000288963318 -0.12393999844789505 2.8657801151275635 1.7780599594116209 -1.0177199840545654 -0.5625799894332886 54.792792315584 60.0 1.0 yes 2682 chrIV_1186227r 8166 essential YDR356W 123 - TCATCACCATTATTGGCATT E|48|Q E|48|K D|47|H D|47|N SPC110 Spindle Pole Component 944.0 0 0 0 0 0.7387564665812192 P32380 0.8994529843330383 0.8996379971504211 0.8015149831771851 0.900596022605896 0.4418604075908661 0.6695989966392517 0.5462695360183716 0.5953994393348694 47.00515021598882 35.0 1.0 no 2683 chrIV_1186259r 8168 essential YDR356W 155 - TTCTCTGCCTTTTCTTAACA R|58|T R|58|K Q|57|H silent|CAG>CAA|Q|57 SPC110 Spindle Pole Component 944.0 0 1 0 0 0.5561633461578822 P32380 0.8890569806098938 0.931436002254486 0.8288440108299255 0.0 0.0 0.12670350074768064 48.064010757936565 35.0 1.0 no 2684 chrIV_1186340 8170 essential YDR356W 233 + TGACAGCTTTCCAGAAATTA D|79|E silent|GAC>GAT|D|79 S|80|R silent|AGC>AGT|S|80 SPC110 Spindle Pole Component 944.0 0 1 0 0 -0.04033914927015084 P32380 0.9384809732437134 0.8605239987373352 1.0 0.0155795281752944 42.37465559506251 35.0 1.0 no 2685 chrIV_1186459r 8173 essential YDR356W 355 - TCTTACTTCTTGTTCTTTCA R|125|T R|125|K V|124|L V|124|I SPC110 Spindle Pole Component 944.0 0 0 0 0 0.7024930538828233 P32380 0.992900013923645 1.026769995689392 0.9321269989013672 0.954712986946106 0.5172795057296753 0.9546060562133788 0.25598394870758057 0.17901715636253354 45.873255069097354 30.0 1.0 no 2686 chrIV_1186670r 8176 essential YDR356W 566 - AGTCATCTGTTTCTTCTTCA D|195|H D|195|N D|194|H D|194|N SPC110 Spindle Pole Component 944.0 0 0 0 0 0.13971269858395471 P32380 0.7962340116500854 0.8992729783058167 0.7922949790954591 0.8976179957389832 0.0 0.0 0.05852871760725975 0.2461592555046081 48.98501661029474 35.0 1.0 no 2687 chrIV_1187312r 8180 essential YDR356W 1208 - CTTCTTCCCTTGAGCCCAAC E|409|Q E|409|K E|408|Q E|408|K SPC110 Spindle Pole Component 944.0 0 0 0 0 -0.14605413278982712 P32380 0.966172993183136 0.9678279757499696 0.959900975227356 0.9480329751968384 0.6135392785072327 0.8755658268928528 0.4514116942882538 0.5456372499465942 57.572245607592784 55.00000000000001 1.0 no 2688 chrIV_1187623r 8181 essential YDR356W 1519 - TTCATCTTCCAACTTTGATT E|513|Q E|513|K D|512|H D|512|N SPC110 Spindle Pole Component 944.0 0 0 0 0 0.08424009943265838 P32380 0.9002659916877747 0.9025980234146118 0.8426210284233093 0.9427239894866944 0.2781350314617157 0.35036590695381165 0.04651831090450287 0.16281841695308685 43.69650338774335 30.0 1.0 no 2689 chrIV_1187735r 8182 essential YDR356W 1631 - TCTCATAGTTTTCTTTCATA E|550|Q E|550|K E|550|D silent|GAG>GAA|E|550 SPC110 Spindle Pole Component 944.0 0 0 0 0 0.17097389792974438 P32380 1.016080021858215 1.0168499946594238 1.0195599794387815 0.1839294731616974 1.0 0.2127753347158432 41.918272270616 25.0 1.0 no 2690 chrIV_1192682 8184 high_effect YDR359C 2183 - TCTGTCTCTGCTGAAATTTA Q|734|H silent|CAG>CAA|Q|734 R|733|T R|733|K EAF1 Esa1p-Associated Factor 982.0 0 0 0 0 0.04215725312364675 Q06337 0.0 0.03433223068714142 0.7377296090126038 43.71100731170157 35.0 0.0 no 2691 chrIV_1192786 8187 high_effect YDR359C 2079 - AAACGCTCAAAACACTGCCA R|699|P R|699|H E|698|D silent|GAG>GAA|E|698 EAF1 Esa1p-Associated Factor 982.0 0 0 0 0 -0.7697840395293938 Q06337 0.0 0.0 0.0 43.98650488473925 45.0 0.0 no 2692 chrIV_1192877r 8189 high_effect YDR359C 1985 + TAACACATATGGCTACAATT N|663|K silent|AAC>AAT|N|663 T|664|R T|664|I EAF1 Esa1p-Associated Factor 982.0 0 0 0 0 0.3093284440474398 Q06337 0.0 0.10770034044981004 0.08970604836940765 38.264689506960615 30.0 0.0 no 2693 chrIV_1193173 8196 high_effect YDR359C 1692 - TCATTAATACCATTATACAG E|571|Q E|571|K EAF1 Esa1p-Associated Factor 982.0 0 0 0 0 -1.9359470433430888 Q06337 0.11827079206705092 0.1374659687280655 35.96595779625926 25.0 0.0 no 2694 chrIV_1193578 8199 high_effect YDR359C 1287 - TCATTTCTTGAAGTATCCGA D|436|H D|436|N R|434|T R|434|K EAF1 Esa1p-Associated Factor 982.0 0 1 0 0 0.7427374267904632 Q06337 0.1357080489397049 0.495450109243393 0.6021255254745483 1.0 44.08305780352015 35.0 0.0 no 2695 chrIV_1193700r 8203 high_effect YDR359C 1162 + CACAGGCAATCAAGGACTAC Q|389|E Q|389|* A|390|G A|390|V EAF1 Esa1p-Associated Factor 982.0 0 0 0 0 -0.4729613521776753 Q06337 0.05021375417709351 0.23643457889556885 0.02707054652273655 44.793911756258815 50.0 0.0 no 2696 chrIV_1194095 8213 high_effect YDR359C 770 - CAACATTGTTCTCGTTATAA V|263|L V|263|I EAF1 Esa1p-Associated Factor 982.0 0 0 0 0 0.15734617492529945 Q06337 0.05603640526533127 1.0 39.10700012620993 30.0 0.0 no 2697 chrIV_1194164r 8214 high_effect YDR359C 698 + GCAACCTGCAGTAAAATTCA Q|234|E Q|234|* P|235|A P|235|S EAF1 Esa1p-Associated Factor 982.0 0 0 0 0 -0.15650278534643874 Q06337 1.0 0.4449132382869721 0.8299704790115356 43.80827985164302 40.0 0.0 no 2698 chrIV_1194240 8221 high_effect YDR359C 625 - TGCTAATGCATTAGGCACTG A|215|P A|215|T EAF1 Esa1p-Associated Factor 982.0 0 0 0 0 1.0349079327775184 Q06337 0.2708866000175476 0.6447176337242126 46.94876079864912 45.0 0.0 no 2699 chrIV_1194361r 8226 high_effect YDR359C 501 + CCACTTGAGTCAACTATGGG L|169|V L|169|F P|168|R P|168|L EAF1 Esa1p-Associated Factor 982.0 0 0 0 0 -0.036660526801187365 Q06337 0.8893095850944519 0.7579436898231506 0.8408095836639404 0.6391466856002808 47.94799260112336 50.0 0.0 no 2700 chrIV_1194397 8228 high_effect YDR359C 468 - ATACCTCCTGTCTTTTCAGC G|162|A G|162|D G|162|R G|162|S EAF1 Esa1p-Associated Factor 982.0 0 0 0 0 0.21694792313983388 Q06337 0.8367175459861755 0.4801971614360809 0.5960973501205444 0.724849283695221 54.200089561850405 45.0 0.0 no 2701 chrIV_1194713 8234 high_effect YDR359C 152 - CATCTGTTAACTCTAGCAGC D|57|H D|57|N EAF1 Esa1p-Associated Factor 982.0 0 0 0 0 0.743562309540261 Q06337 0.014191871508955956 0.18236678838729856 47.47513888190088 45.0 0.0 no 2702 chrIV_1194784 8237 high_effect YDR359C 81 - TCAATTAAGTCATCTGCCTT D|34|H D|34|N EAF1 Esa1p-Associated Factor 982.0 0 0 0 0 -0.37894057776204026 Q06337 0.13183078169822693 0.5408306121826172 45.447026560419204 35.0 0.0 no 2703 chrIV_1195953r 8246 essential YDR361C 288 + ACCACCACAATTAAAACAGA silent|ACC>ACG|T|97 silent|ACC>ACT|T|97 T|97|S T|97|I BCP1 283.0 0 0 0 1 0.8614665941286845 Q06338 0.9491789937019348 0.9472420215606691 0.8201408982276917 0.20105090737342834 39.56226931475072 35.0 0.0 no 2704 chrIV_1197232r 8250 essential YDR362C 1443 + GTCAGTACAGTTGCGGTGGA silent|GTC>GTG|V|482 silent|GTC>GTT|V|482 TFC6 Transcription Factor C 672.0 0 0 0 0 0.5574677095131488 Q06339 54.81627050396339 55.00000000000001 0.0 no 2705 chrIV_1197382r 8254 essential YDR362C 1293 + TCTCCTACTACTGTTGTTTG P|433|A P|433|S S|432|C S|432|F TFC6 Transcription Factor C 672.0 0 0 0 0 -0.1925831444453114 Q06339 0.9562489986419678 0.9498909711837769 0.945252001285553 0.9294660091400146 0.101535364985466 0.5117296576499939 0.0047994344495236865 0.002524547511711717 48.17705049918732 40.0 0.0 no 2706 chrIV_1197437r 8256 essential YDR362C 1238 + GCCTTCTTTGACTTTATCCC P|414|R P|414|L P|414|A P|414|S TFC6 Transcription Factor C 672.0 0 0 0 0 -1.0244840590622248 Q06339 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.04259917140007019 0.04646701738238335 1.0 0.4190093278884888 54.4296817713585 45.0 0.0 no 2707 chrIV_1197553r 8259 essential YDR362C 1122 + TGTCACGCACCTCATCTGGT H|376|D H|376|Y H|376|Q silent|CAC>CAT|H|376 TFC6 Transcription Factor C 672.0 0 1 0 0 -0.8538109534189241 Q06339 0.9473130106925964 0.9489949941635132 0.9588389992713928 0.3732579648494721 0.06270063668489456 0.4234810471534729 -1.562000036239624 -0.06700000166893005 -0.43140000104904175 57.094433342865216 55.00000000000001 0.0 no 2708 chrIV_1197603 8261 essential YDR362C 1075 - TTCACCAAATGAGTGTACAA E|365|Q E|365|K G|364|A G|364|D TFC6 Transcription Factor C 672.0 0 0 0 0 -2.2706879313818487 Q06339 0.956179976463318 0.9475290179252625 0.9499930143356324 0.9446240067481996 0.026602905243635174 0.021032838150858883 0.0 0.0 40.52118006474024 35.0 0.0 yes 2709 chrIV_1198033 8268 essential YDR362C 645 - GCACTTTCCTTTTTACACGG S|221|T S|221|N A|222|P A|222|T TFC6 Transcription Factor C 672.0 0 0 0 0 1.2430760233240203 Q06339 0.9512869715690612 0.9536849856376648 0.9573720097541808 0.9523990154266356 0.9678717851638794 0.5390450358390808 0.31699055433273315 0.7361328005790709 0.38760000467300415 2.175800085067749 49.86449258469611 45.0 0.0 no 2710 chrIV_1198240 8269 essential YDR362C 438 - TTCTGTCCTAGACTTGACCC Q|152|H silent|CAG>CAA|Q|152 G|151|A G|151|E TFC6 Transcription Factor C 672.0 0 0 0 0 0.421210656477964 Q06339 0.9570760130882264 0.9499930143356324 0.9438679814338684 0.05041879788041115 0.5441843271255493 0.8368794322013855 54.314546723897934 50.0 0.0 no 2711 chrIV_1198315 8273 essential YDR362C 363 - ACAGTATTTCTTCTTCCACT V|128|L V|128|I TFC6 Transcription Factor C 672.0 0 0 0 0 -0.43602177505909545 Q06339 0.9539830088615416 0.9574310183525084 0.4790328145027161 0.4243740141391754 48.351274389412936 35.0 0.0 no 2712 chrIV_1198564 8277 essential YDR362C 114 - TTCTTAGATGCGTTTCTCCT K|44|N silent|AAG>AAA|K|44 TFC6 Transcription Factor C 672.0 0 0 0 0 0.3464687016744976 Q06339 0.9355990290641784 0.01899445429444313 50.947742065624645 40.0 0.0 no 2713 chrIV_1198642 8280 essential YDR362C 36 - TCTGCTACCACAGATTTTCT E|19|Q E|19|K A|18|P A|18|T TFC6 Transcription Factor C 672.0 0 1 0 0 -0.14649505801894708 Q06339 0.956179976463318 0.9475290179252625 0.9573720097541808 0.9523990154266356 0.5514815449714661 0.6388320326805115 0.2998285889625549 0.7326359748840332 49.341810031419975 40.0 0.0 no 2714 chrIV_1205115 8283 essential YDR365C 1249 - TTTCTCGTTTCCTCCTTCCA E|422|D silent|GAG>GAA|E|422 E|422|Q E|422|K ESF1 Eighteen S rRNA Factor 628.0 0 1 0 0 -1.4081227610002751 Q06344 0.94931298494339 0.956179976463318 0.9475290179252625 0.6136773228645325 0.557284951210022 0.8992799520492554 57.94442065373824 45.0 0.0 no 2715 chrIV_1205128r 8284 essential YDR365C 1233 + ACATTTACTCCAGCCTTGGA T|412|R T|412|I ESF1 Eighteen S rRNA Factor 628.0 0 0 0 0 0.5389774575138022 Q06344 0.9476869702339172 0.9472420215606691 0.0 0.0 52.621011246515714 45.0 0.0 no 2716 chrIV_1205166 8285 essential YDR365C 1198 - TTCTTCATCTTCATCGTTAG E|406|Q E|406|K E|405|Q E|405|K ESF1 Eighteen S rRNA Factor 628.0 0 0 0 0 0.8127516696946 Q06344 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.032906446605920785 0.02644552662968636 0.28128474950790405 0.3659494519233704 44.71918441841433 35.0 0.0 no 2717 chrIV_1205178 8286 essential YDR365C 1186 - ATCGTTAGGGGTTTCTTTCT D|402|H D|402|N ESF1 Eighteen S rRNA Factor 628.0 0 0 0 0 -0.5880688354857168 Q06344 0.9486550092697144 0.956179976463318 0.026948831975460046 0.28337162733078003 50.59702692114757 40.0 0.0 no 2718 chrIV_1205165 8288 essential YDR365C 1199 - CTTCTTCATCTTCATCGTTA E|406|Q E|406|K E|405|Q E|405|K ESF1 Eighteen S rRNA Factor 628.0 0 0 0 0 -0.3774199340392618 Q06344 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.032906446605920785 0.02644552662968636 0.28128474950790405 0.3659494519233704 46.60202171902216 35.0 0.0 no 2719 chrIV_1205473 8294 essential YDR365C 891 - TCATCAAAAGTCATACCATC D|304|H D|304|N D|303|H D|303|N ESF1 Eighteen S rRNA Factor 628.0 0 0 0 0 1.2931251577992668 Q06344 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.01696160063147545 0.07767976820468903 0.005683897528797388 0.016922088339924812 40.23969042845891 35.0 0.0 no 2720 chrIV_1205502r 8296 essential YDR365C 859 + CCGCTAATATGTTCGATTTA A|288|G A|288|V silent|ACC>ACG|T|287 silent|ACC>ACT|T|287 ESF1 Eighteen S rRNA Factor 628.0 0 0 0 0 -0.5270705933503695 Q06344 0.9484469890594482 0.9504740238189696 0.0 0.0 43.38878528101686 35.0 0.0 no 2721 chrIV_1205695r 8301 essential YDR365C 666 + TCTGATTCTGATATGGACAT S|223|C S|223|F ESF1 Eighteen S rRNA Factor 628.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.5028926027491872 Q06344 0.945252001285553 0.9294660091400146 0.043419227004051215 0.04325474798679352 42.233198784842614 35.0 0.0 no 2722 chrIV_1205891 8305 essential YDR365C 473 - TCAAATCCTCAGATTTAACA L|164|F silent|TTG>TTA|L|164 D|163|H D|163|N ESF1 Eighteen S rRNA Factor 628.0 0 0 0 0 -0.8747191280799399 Q06344 0.9587849974632264 0.9486550092697144 0.956179976463318 0.02261647023260593 0.0 0.0 39.12332225063767 30.0 0.0 no 2723 chrIV_1206003 8308 essential YDR365C 361 - GCTTTCAACTTCACTTTCTC S|127|T S|127|N E|126|Q E|126|K ESF1 Eighteen S rRNA Factor 628.0 0 0 0 0 0.2845318758537235 Q06344 0.9512869715690612 0.9536849856376648 0.956179976463318 0.9475290179252625 0.4972463548183441 0.4290599524974823 0.4022817015647888 0.52553790807724 47.60954065450722 40.0 0.0 no 2724 chrIV_1206088r 8309 essential YDR365C 273 + ACAGTAGTGGACCGTGCCCG T|92|R T|92|I ESF1 Eighteen S rRNA Factor 628.0 0 1 0 0 0.5416409463317973 Q06344 0.9476869702339172 0.9472420215606691 0.5260295271873474 0.2117266207933426 59.00193529361946 65.0 0.0 no 2725 chrIV_1206071 8310 essential YDR365C 293 - AATCATCAGGAACTTCACCA D|104|H D|104|N D|103|H D|103|N ESF1 Eighteen S rRNA Factor 628.0 0 0 0 0 -0.6482280959415209 Q06344 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.10459477454423904 0.4015231728553772 0.1210416704416275 0.5799055099487305 44.8548200071205 40.0 0.0 no 2726 chrIV_1206072 8311 essential YDR365C 292 - ATCATCAGGAACTTCACCAC D|104|H D|104|N D|103|H D|103|N ESF1 Eighteen S rRNA Factor 628.0 0 0 0 0 -0.2355521602808968 Q06344 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.10459477454423904 0.4015231728553772 0.1210416704416275 0.5799055099487305 46.839169526483204 45.0 0.0 no 2727 chrIV_1206183r 8313 essential YDR365C 178 + TCAAAAATGCGCAGAATAAC I|60|M silent|ATC>ATT|I|60 ESF1 Eighteen S rRNA Factor 628.0 0 1 0 0 0.3608322621406487 Q06344 0.9598389863967896 0.038903873413801186 34.968457163630774 35.0 0.0 no 2728 chrIV_1206221 8314 essential YDR365C 143 - TGTCAACCTTAGATTTATGC D|54|H D|54|N V|53|L V|53|I ESF1 Eighteen S rRNA Factor 628.0 0 1 0 0 -0.12134313970732424 Q06344 0.9486550092697144 0.956179976463318 0.9539830088615416 0.9574310183525084 0.0 0.0 0.053746022284030914 0.5064069032669067 43.19397241005839 35.0 0.0 no 2729 chrIV_1206347 8316 essential YDR365C 17 - CATCTACACCTTCCTTCTTT D|12|H D|12|N V|11|L V|11|I ESF1 Eighteen S rRNA Factor 628.0 0 0 0 0 -0.0481841716941521 Q06344 0.9486550092697144 0.956179976463318 0.9539830088615416 0.9574310183525084 0.0 0.0 0.30491551756858826 0.19714419543743134 51.340861896501686 40.0 0.0 no 2730 chrIV_1222814r 8317 essential YDR373W 58 - TTCTCTTCTATCAAAATAGG E|26|Q E|26|K R|25|T R|25|K FRQ1 FReQuenin homolog 190.0 0 0 0 0 -0.15792116871290438 Q06389 0.9078890085220336 0.8767830133438109 0.8830710053443909 0.9088720083236694 0.16133038699626925 0.004238178487867117 0.15197062492370605 1.0 -0.09700000286102296 -1.1023999452590942 0.07540000230073929 -0.6769999861717224 37.164587162438686 30.0 1.0 no 2731 chrIV_1226869 8324 essential YDR376W 47 + GACTGTATCCATTGTTGGAT T|17|S T|17|I ARH1 Adrenodoxin Reductase Homolog 493.0 0 0 0 0 -0.0347484456790369 P48360 0.9491789937019348 0.9472420215606691 0.18817703425884247 0.059937875717878335 47.540119292312575 40.0 1.0 no 2732 chrIV_1226941 8327 essential YDR376W 119 + TCCATTAAATGTTACTATAT P|41|R P|41|L P|41|A P|41|S ARH1 Adrenodoxin Reductase Homolog 493.0 0 0 0 0 -0.6521507827753434 P48360 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.2709464132785797 0.15011030435562134 0.526153564453125 0.6189688444137573 35.65672456764236 20.0 1.0 no 2733 chrIV_1226978r 8330 essential YDR376W 159 - CCATATCTACTTAAACCAAA G|60|R G|60|S R|58|T R|58|K ARH1 Adrenodoxin Reductase Homolog 493.0 0 0 0 0 -1.4270775752618092 P48360 0.941340982913971 0.951104998588562 0.932735025882721 0.955805003643036 0.0 0.0 0.0 0.0 38.31711075353496 30.0 1.0 no 2734 chrIV_1227017r 8331 essential YDR376W 198 - TCTTCACAATTTTTGACTTC E|73|Q E|73|K E|72|Q E|72|K ARH1 Adrenodoxin Reductase Homolog 493.0 0 0 0 0 0.7240945543722288 P48360 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.07422638684511185 0.05946791172027587 0.27236253023147583 0.031391628086566925 40.420189570187226 30.0 1.0 no 2735 chrIV_1227212r 8334 essential YDR376W 393 - CCTTTTGTTCCGAGTTCGCC G|138|R G|138|R ARH1 Adrenodoxin Reductase Homolog 493.0 0 0 0 0 0.449212888060234 P48360 0.941340982913971 0.941340982913971 0.01322635728865862 0.01322635728865862 57.9423747768775 55.00000000000001 1.0 no 2736 chrIV_1227668r 8343 essential YDR376W 849 - TTCTTCGAACGTTCATTAAA K|289|N silent|AAG>AAA|K|289 silent|TCG>TCC|S|288 silent|TCG>TCA|S|288 ARH1 Adrenodoxin Reductase Homolog 493.0 0 0 0 0 0.4724753918549427 P48360 0.9355990290641784 38.355647222025816 30.0 1.0 no 2737 chrIV_1227762r 8346 essential YDR376W 943 - ATCGTCTCTATTAATTTTCA D|321|H D|321|N D|320|H D|320|N ARH1 Adrenodoxin Reductase Homolog 493.0 0 0 0 0 -2.326124208596865 P48360 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.08592601120471954 0.5218166708946228 0.1268504559993744 0.5409753918647766 40.122084018769776 25.0 1.0 yes 2738 chrIV_1227835 8347 essential YDR376W 1013 + TAACAGTTTGCAACCCTTGA N|339|K silent|AAC>AAT|N|339 ARH1 Adrenodoxin Reductase Homolog 493.0 0 0 0 0 0.3022168062021351 P48360 0.9439849853515624 0.5178365111351013 46.76483925625496 40.0 1.0 no 2739 chrIV_1236625r 8351 essential YDR381W 70 - ACCACGAGTACCACCGACAC G|30|R G|30|S G|30|A G|30|D YRA1 Yeast RNA Annealing protein 226.0 0 1 0 0 -0.28338009534875075 Q12159 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.8341183066368103 0.19801998138427732 0.2234136164188385 0.11695221811532976 53.29869708966879 60.0 1.0 no 2740 chrIV_1236654r 8354 essential YDR381W 99 - ACTTGCTTACCAACTCTTCT V|40|L V|40|I K|38|N silent|AAG>AAA|K|38 YRA1 Yeast RNA Annealing protein 226.0 0 1 0 0 -1.4521339009454055 Q12159 0.9539830088615416 0.9574310183525084 0.9355990290641784 0.5234307646751404 1.0 0.08350926637649536 49.2272703663773 40.0 1.0 no 2741 chrIV_1236813r 8361 essential YDR381W 258 - GCATCCTGCTTAATGTCCCT A|93|P A|93|T D|92|H D|92|N YRA1 Yeast RNA Annealing protein 226.0 0 1 0 0 -0.055611952597340135 Q12159 0.9573720097541808 0.9523990154266356 0.9486550092697144 0.956179976463318 0.31888365745544434 0.7262151837348938 0.11584285646677014 0.4187786281108856 2.1700601577758794 1.7441500425338743 57.4384397234199 50.0 1.0 no 2742 chrIV_1237687 8363 essential YDR381W 363 + GCTAACATCACATTCAAAAA A|122|G A|122|V N|123|K silent|AAC>AAT|N|123 YRA1 Yeast RNA Annealing protein 226.0 0 0 0 0 0.20036890811286973 Q12159 0.9484469890594482 0.9504740238189696 0.9439849853515624 0.0 0.0 0.03877534344792366 35.789065409038464 30.0 1.0 no 2743 chrIV_1250446 8370 high_effect YDR388W 260 + CCCTAACGCTACCATACCAG P|88|R P|88|L P|88|A P|88|S RVS167 Reduced Viability on Starvation 482.0 0 0 0 0 0.5018998194601281 P39743 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.11116813868284224 0.3721950650215149 0.24790482223033905 0.13226838409900665 52.94190596438933 55.00000000000001 1.0 no 2744 chrIV_1250459 8371 high_effect YDR388W 273 + ATACCAGAGGACAACCCACA P|93|A P|93|S P|93|R P|93|L RVS167 Reduced Viability on Starvation 482.0 0 0 0 0 -0.04011958058357337 P39743 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.837436318397522 0.8005700707435608 0.5309408307075499 0.3698343336582184 50.21582396429949 50.0 1.0 no 2745 chrIV_1250473r 8374 high_effect YDR388W 290 - CACTTGCTTCAATACCTTGT S|103|T S|103|N A|102|P A|102|T RVS167 Reduced Viability on Starvation 482.0 0 0 0 0 0.008418070686526918 P39743 0.9512869715690612 0.9536849856376648 0.9573720097541808 0.9523990154266356 0.11856117099523544 0.04557475820183754 0.07727465033531189 0.16309583187103271 47.90279066473988 40.0 1.0 no 2746 chrIV_1250474r 8376 high_effect YDR388W 291 - TCACTTGCTTCAATACCTTG S|103|T S|103|N E|104|Q E|104|K RVS167 Reduced Viability on Starvation 482.0 0 0 0 0 0.7052683215273826 P39743 0.9512869715690612 0.9536849856376648 0.956179976463318 0.9475290179252625 0.11856117099523544 0.04557475820183754 0.06582802534103394 0.06843011826276779 46.35974458842378 40.0 1.0 no 2747 chrIV_1250576r 8380 high_effect YDR388W 393 - ATCTTCAACAGTTCCTGGCA K|137|N silent|AAG>AAA|K|137 L|136|F silent|TTG>TTA|L|136 RVS167 Reduced Viability on Starvation 482.0 0 0 0 0 0.4371687946340909 P39743 0.9355990290641784 0.9587849974632264 0.06838058680295944 0.10481065511703493 51.943900271223924 45.0 1.0 no 2748 chrIV_1250706r 8381 high_effect YDR388W 523 - ATACAATCTTTCTTCGTCTT L|180|F silent|TTG>TTA|L|180 RVS167 Reduced Viability on Starvation 482.0 0 0 0 0 0.05876402612971399 P39743 0.9587849974632264 0.020374944433569908 43.03396517791441 30.0 1.0 no 2749 chrIV_1250996 8384 high_effect YDR388W 810 + ACTATTACACACTTTAAACT T|271|S T|271|I RVS167 Reduced Viability on Starvation 482.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.3484488526011205 P39743 0.9491789937019348 0.9472420215606691 1.0 0.07219699025154114 35.95194508539254 25.0 1.0 no 2750 chrIV_1251140 8393 high_effect YDR388W 954 + GCCACTTCTCCAACCCCTAC silent|GCC>GCG|A|319 silent|GCC>GCT|A|319 A|319|G A|319|V RVS167 Reduced Viability on Starvation 482.0 0 0 0 0 -0.6310448943496539 P39743 0.9484469890594482 0.9504740238189696 0.5109236240386963 0.3640916347503662 60.737851962482516 60.0 1.0 no 2751 chrIV_1251146 8395 high_effect YDR388W 960 + TCTCCAACCCCTACAGGATA P|322|A P|322|S S|321|C S|321|F RVS167 Reduced Viability on Starvation 482.0 0 1 0 0 -0.6584242817770799 P39743 0.9562489986419678 0.9498909711837769 0.945252001285553 0.9294660091400146 0.7132478952407837 0.5550987720489502 0.05312095582485199 0.05128907039761543 54.26258109286232 50.0 1.0 no 2752 chrIV_1251153r 8397 high_effect YDR388W 970 - ACCATAACCGTATCCTGTAG G|330|R G|330|S G|330|A G|330|D RVS167 Reduced Viability on Starvation 482.0 0 0 0 0 0.08248251109310976 P39743 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.5224378705024719 0.7693061232566833 0.7532685995101929 0.653722882270813 48.688423694305925 45.0 1.0 no 2753 chrIV_1255632 8414 essential YDR390C 1196 - AATCAGTATACTTAGTAGTT D|405|H D|405|N UBA2 UBiquitin Activating 636.0 0 1 0 0 0.0245810966417509 P52488 0.9486550092697144 0.956179976463318 0.09612622112035753 0.5921651721000671 37.73328157504341 25.0 0.0 no 2754 chrIV_1255633 8415 essential YDR390C 1195 - ATCAGTATACTTAGTAGTTG D|405|H D|405|N UBA2 UBiquitin Activating 636.0 0 1 0 0 0.6152140755044351 P52488 0.9486550092697144 0.956179976463318 0.09612622112035753 0.5921651721000671 39.27803535214707 30.0 0.0 no 2755 chrIV_1255862 8418 essential YDR390C 966 - TCAATATGATTTTGCTCTTT E|329|Q E|329|K UBA2 UBiquitin Activating 636.0 0 0 0 0 -0.4247790266571868 P52488 0.956179976463318 0.9475290179252625 0.2246713787317276 0.2903446555137634 40.1024944001751 25.0 0.0 no 2756 chrIV_1256067r 8419 essential YDR390C 758 + TCTTAATAAATTATTCATTC L|254|V L|254|F UBA2 UBiquitin Activating 636.0 0 0 0 0 1.2013523387037344 P52488 0.9512209892272948 0.9587849974632264 0.9290809631347656 0.2191919982433319 30.300880789813217 15.0 0.0 no 2757 chrIV_1256375r 8425 essential YDR390C 450 + TACATGCAGCCTATTATCCC Y|151|* silent|TAC>TAT|Y|151 Q|153|E Q|153|* UBA2 UBiquitin Activating 636.0 0 0 0 0 -1.4353254442691707 P52488 0.9590039849281312 0.2717982828617096 52.48260323885768 45.0 0.0 no 2758 chrIV_1256374r 8426 essential YDR390C 451 + ACATGCAGCCTATTATCCCC Y|151|* silent|TAC>TAT|Y|151 Q|153|E Q|153|* UBA2 UBiquitin Activating 636.0 0 0 0 0 -1.0752759316444556 P52488 0.9590039849281312 0.2717982828617096 56.61805563180627 50.0 0.0 no 2759 chrIV_1256411 8429 essential YDR390C 417 - GCTGTTCCAGATTCTATTAA A|146|P A|146|T G|144|A G|144|E UBA2 UBiquitin Activating 636.0 0 0 0 0 -5.501682670699964 P52488 0.9573720097541808 0.9523990154266356 0.9499930143356324 0.9438679814338684 0.11226698756217957 1.0 0.0 0.0 45.61355422322902 35.0 0.0 yes 2760 chrIV_1256521r 8431 essential YDR390C 304 + TTTCTACCTTCCCACTGCAT S|103|C S|103|F T|104|S T|104|I UBA2 UBiquitin Activating 636.0 0 0 0 0 0.31771758860035376 P52488 0.945252001285553 0.9294660091400146 0.9491789937019348 0.9472420215606691 0.03870092332363129 0.03736041113734245 0.8214185237884521 0.5215513706207275 55.54162323440522 45.0 0.0 no 2761 chrIV_1256764 8436 essential YDR390C 64 - ACCGACCAGAAGACATCTTG G|28|R G|28|S G|28|A G|28|D UBA2 UBiquitin Activating 636.0 0 0 0 0 -4.390833056033607 P52488 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 47.19833627316802 50.0 0.0 yes 2762 chrIV_1256765r 8437 essential YDR390C 60 + TCCTCAAGATGTCTTCTGGT silent|TCC>TCG|S|21 silent|TCC>TCT|S|21 S|21|C S|21|F UBA2 UBiquitin Activating 636.0 0 0 0 0 -1.147607413733147 P52488 0.945252001285553 0.9294660091400146 0.04947856441140175 0.057489834725856774 51.75115567839555 45.0 0.0 no 2763 chrIV_1261753 8440 essential YDR394W 72 + TCATTGTTGGCTCAACTCAA S|25|* S|25|L RPT3 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 428.0 0 0 0 0 0.7730546434986041 P33298 46.26372247129859 40.0 1.0 no 2764 chrIV_1261796r 8441 essential YDR394W 118 - ATCAGAATTCACATTAGACA D|46|H D|46|N RPT3 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 428.0 0 0 0 0 0.22270830920949505 P33298 0.08498427271842958 0.14697107672691345 38.27060338287527 30.0 1.0 no 2765 chrIV_1261797r 8442 essential YDR394W 119 - TATCAGAATTCACATTAGAC D|46|H D|46|N RPT3 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 428.0 0 0 0 0 0.07524460062306199 P33298 0.08498427271842958 0.14697107672691345 36.30900364555714 30.0 1.0 no 2766 chrIV_1261899r 8443 essential YDR394W 221 - TCTTCAATTCACGTTTCAAA K|80|N silent|AAG>AAA|K|80 L|79|F silent|TTG>TTA|L|79 RPT3 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 428.0 0 0 0 0 -0.0019054279976448152 P33298 0.4894437491893768 0.7238175272941589 0.3837999999523163 39.75167464281078 30.0 1.0 no 2767 chrIV_1262018r 8446 essential YDR394W 340 - AACGACATAACTCATACCTG V|120|L V|120|I V|119|L V|119|I RPT3 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 428.0 0 0 0 0 -0.6650199802078306 P33298 0.00644274242222309 0.009738082066178322 0.5902069211006165 0.4643660187721253 0.3287000060081482 -0.18140000104904172 0.9223999977111816 -0.6471999883651733 40.765553200126185 40.0 1.0 no 2768 chrIV_1262179r 8451 essential YDR394W 501 - ACATCTGCATAAGTGACGTC V|174|L V|174|I D|173|H D|173|N RPT3 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 428.0 0 0 0 0 -0.4626225551649673 P33298 0.011459914967417715 1.0 0.002119239186868072 0.02994339913129806 0.6360999941825867 0.5192999839782715 0.4874700009822846 0.30906999111175537 45.65300959004651 45.0 1.0 no 2769 chrIV_1262185 8452 essential YDR394W 504 + GTCACTTATGCAGATGTTGG silent|GTC>GTG|V|169 silent|GTC>GTT|V|169 T|170|S T|170|I RPT3 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 428.0 0 0 0 0 -2.026851024936621 P33298 0.7585873007774353 0.013659216463565826 47.60157909031392 45.0 1.0 yes 2770 chrIV_1262507r 8463 essential YDR394W 829 - ATCAAAACGCTTTGTGGCAA D|283|H D|283|N RPT3 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 428.0 0 1 0 0 -1.038501173925508 P33298 0.0032079671509563927 0.0604366846382618 -0.2847999930381775 -0.22405000030994413 43.11727072117139 40.0 1.0 no 2771 chrIV_1266644 8472 essential YDR397C 116 - TTTCGGAAGCCATCGAGGAC E|45|Q E|45|K NCB2 Negative Cofactor B 146.0 0 0 0 0 -0.54308336582244 Q92317 50.11508243223568 55.00000000000001 0.0 no 2772 chrIV_1267589r 8482 essential YDR398W 121 - ATTCCACACTGTATCAACTC W|46|C W|46|* W|46|S W|46|* UTP5 U Three Protein 643.0 0 0 0 0 0.3622882382980679 Q04177 0.8858469724655151 0.8858469724655151 0.02816433273255825 0.0410044863820076 45.65849687490896 40.0 1.0 no 2773 chrIV_1267586r 8483 essential YDR398W 118 - CCACACTGTATCAACTCCGG silent|GTG>GTC|V|45 silent|GTG>GTA|V|45 W|46|S W|46|* UTP5 U Three Protein 643.0 0 0 0 0 -3.545084551345523 Q04177 0.8858469724655151 0.0410044863820076 51.43130379820435 55.00000000000001 1.0 yes 2774 chrIV_1267671 8485 essential YDR398W 200 + CCTGGCTTCTTCCGACACAG L|68|V silent|CTG>TTG|L|68 A|69|G A|69|V UTP5 U Three Protein 643.0 0 0 0 0 -1.5353518041628709 Q04177 0.9512209892272948 0.9484469890594482 0.9504740238189696 0.5087076425552368 0.792399525642395 0.15193204581737518 56.60576638914921 60.0 1.0 no 2775 chrIV_1267752 8488 essential YDR398W 281 + AGTCACCTATAAATTCACTA silent|GTC>GTG|V|95 silent|GTC>GTT|V|95 T|96|S T|96|I UTP5 U Three Protein 643.0 0 0 0 0 -0.6239719069721114 Q04177 0.9491789937019348 0.9472420215606691 0.01299209613353014 0.8923283815383911 40.35007253411726 30.0 1.0 no 2776 chrIV_1267753 8489 essential YDR398W 282 + GTCACCTATAAATTCACTAC silent|GTC>GTG|V|95 silent|GTC>GTT|V|95 T|96|S T|96|I UTP5 U Three Protein 643.0 0 0 0 0 0.5771764614542534 Q04177 0.9491789937019348 0.9472420215606691 0.01299209613353014 0.8923283815383911 40.74848938533472 35.0 1.0 no 2777 chrIV_1267754 8490 essential YDR398W 283 + TCACCTATAAATTCACTACG T|96|S T|96|I silent|GTC>GTG|V|95 silent|GTC>GTT|V|95 UTP5 U Three Protein 643.0 0 0 0 0 -1.001061864759743 Q04177 0.9491789937019348 0.9472420215606691 0.01299209613353014 0.8923283815383911 39.792376606534155 35.0 1.0 no 2778 chrIV_1267788 8492 essential YDR398W 317 + AATCAAAGACATAGACTTGA I|107|M silent|ATC>ATT|I|107 UTP5 U Three Protein 643.0 0 0 0 0 0.9513848983953096 Q04177 0.9598389863967896 0.00915954541414976 34.913938671957176 30.0 1.0 no 2779 chrIV_1268135r 8499 essential YDR398W 667 - TTCAGCCACAAGGACGCATT E|229|Q E|229|K A|228|P A|228|T UTP5 U Three Protein 643.0 0 0 0 0 0.11157978339047656 Q04177 0.956179976463318 0.9475290179252625 0.9573720097541808 0.9523990154266356 1.0 0.1792990267276764 0.22341084480285645 0.6076251268386841 51.13100871773634 50.0 1.0 no 2780 chrIV_1268404r 8504 essential YDR398W 936 - CACTGCAAGTTCTTGAAGTA Q|318|H silent|CAG>CAA|Q|318 L|317|F silent|TTG>TTA|L|317 UTP5 U Three Protein 643.0 0 0 0 0 -0.16635618802520888 Q04177 0.9570760130882264 0.9587849974632264 0.054502513259649284 0.04112595319747925 43.846412077859725 40.0 1.0 no 2781 chrIV_1268436r 8506 essential YDR398W 968 - TTTCGACGGTATATTCATTA E|329|Q E|329|K V|328|L V|328|I UTP5 U Three Protein 643.0 0 0 0 0 1.281904370665066 Q04177 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.5851225256919861 0.9322653412818908 0.6535085439682007 0.6133862137794495 40.99539760067626 30.0 1.0 no 2782 chrIV_1268488 8507 essential YDR398W 1017 + TCCGCCGATCGCGATCTACA silent|TCC>TCG|S|340 silent|TCC>TCT|S|340 S|340|C S|340|F UTP5 U Three Protein 643.0 0 0 0 0 -0.9204830629511628 Q04177 0.945252001285553 0.9294660091400146 0.07674069702625275 0.1490323394536972 55.972214051987855 60.0 1.0 no 2783 chrIV_1268524 8509 essential YDR398W 1053 + TCAGCCACCAACTACGTGGA S|352|* S|352|L A|353|G A|353|V UTP5 U Three Protein 643.0 0 1 0 0 -0.4887323317222066 Q04177 0.9298099875450134 0.9484469890594482 0.9504740238189696 0.02446269989013672 0.08300528675317764 0.7714871168136597 53.44962196448785 55.00000000000001 1.0 no 2784 chrIV_1268705r 8515 essential YDR398W 1237 - TTTCCCACTAATCCTTGCGA silent|GGG>GGC|G|418 silent|GGG>GGA|G|418 G|418|A G|418|E UTP5 U Three Protein 643.0 0 0 0 0 -0.9011709567040354 Q04177 0.9499930143356324 0.9438679814338684 0.8321148753166199 1.0 52.38577775882038 45.0 1.0 no 2785 chrIV_1268808 8518 essential YDR398W 1337 + ATCAAATGATCATTCACTGT S|447|* S|447|L UTP5 U Three Protein 643.0 0 0 0 0 -0.8074326754390987 Q04177 0.9298099875450134 0.009500215761363506 39.31033742259972 30.0 1.0 no 2786 chrIV_1268877 8524 essential YDR398W 1406 + CTTCCGTCTGAAACCAGCAC F|470|L silent|TTC>TTT|F|470 R|471|G R|471|C UTP5 U Three Protein 643.0 0 0 0 0 0.3246777698941853 Q04177 0.9387490153312684 0.8994590044021606 0.8926740288734436 0.8006494045257568 0.009172944352030754 0.001229006564244628 51.51769064731361 55.00000000000001 1.0 no 2787 chrIV_1268107 8527 essential YDR398W 636 + AACGTATATGATATTCATTC N|213|K silent|AAC>AAT|N|213 UTP5 U Three Protein 643.0 0 0 0 0 0.20563887514314388 Q04177 0.9439849853515624 0.0 35.35990954299439 25.0 1.0 no 2788 chrIV_1276802 8530 essential YDR404C 348 - GCATTAAAGGTTAAATCTTG A|123|P A|123|T RPB7 RNA Polymerase B 171.0 0 0 0 0 0.15293074649935 P34087 1.0 0.031967230141162865 4.588019847869873 0.9475200176239014 -1.478960037231445 0.4753200113773346 35.91761785555258 30.0 0.0 no 2789 chrIV_1276877r 8533 essential YDR404C 270 + GTCGTTTCATGTTCTCAGCA silent|GTC>GTG|V|91 silent|GTC>GTT|V|91 RPB7 RNA Polymerase B 171.0 0 0 0 0 -0.6664280095624038 P34087 53.00923075075593 45.0 0.0 no 2790 chrIV_1276907 8534 essential YDR404C 243 - TCCACTACTTCCCCTTTAAA silent|GTG>GTC|V|87 silent|GTG>GTA|V|87 D|88|H D|88|N RPB7 RNA Polymerase B 171.0 0 0 0 0 -2.1180491555000125 P34087 0.0021309508010745053 0.005856831092387439 0.6695600152015686 0.1178399994969368 50.47419797479382 40.0 0.0 yes 2791 chrIV_1285057r 8545 essential YDR407C 2859 + GCTGTTCCATTTAATTTCAC A|954|G A|954|V P|956|A P|956|S TRS120 TRapp Subunit 1289.0 0 0 0 0 0.014055707286598051 Q04183 0.9484469890594482 0.9504740238189696 0.9562489986419678 0.9498909711837769 0.4031597971916199 0.3252799212932587 0.419778972864151 0.4373389184474945 45.34152928471934 35.0 0.0 no 2792 chrIV_1285114 8546 essential YDR407C 2805 - TCATTTGGCTTGATTACCGT E|942|Q E|942|K TRS120 TRapp Subunit 1289.0 0 0 0 0 -0.1335033512810012 Q04183 0.956179976463318 0.9475290179252625 0.04691887274384498 0.04539930447936058 49.075786765538396 40.0 0.0 no 2793 chrIV_1285130r 8548 essential YDR407C 2786 + ACGTATTATTAAATTACCAA R|930|G R|930|C TRS120 TRapp Subunit 1289.0 0 0 0 0 0.4878302334460503 Q04183 0.8994590044021606 0.8926740288734436 0.05251801759004593 0.007598132360726595 34.14374405557953 20.0 0.0 no 2794 chrIV_1285877 8557 essential YDR407C 2042 - GTCTATTTTCTAGGCTTTCA R|687|T R|687|K TRS120 TRapp Subunit 1289.0 0 1 0 0 0.11163893804473064 Q04183 0.932735025882721 0.955805003643036 0.5287007689476013 1.0 48.17265317389217 35.0 0.0 no 2795 chrIV_1285900 8560 essential YDR407C 2019 - CTGCTAACATCTGACTCTAA S|679|T S|679|N TRS120 TRapp Subunit 1289.0 0 1 0 0 -0.07134901278401679 Q04183 0.9512869715690612 0.9536849856376648 0.703869104385376 0.5750367641448975 43.201529583778274 40.0 0.0 no 2796 chrIV_1285901 8561 essential YDR407C 2018 - TGCTAACATCTGACTCTAAT S|679|T S|679|N V|678|L V|678|I TRS120 TRapp Subunit 1289.0 0 1 0 0 -0.7653942034875358 Q04183 0.9512869715690612 0.9536849856376648 0.9539830088615416 0.9574310183525084 0.703869104385376 0.5750367641448975 0.19460390508174896 1.0 41.394719559539574 35.0 0.0 no 2797 chrIV_1285966 8562 essential YDR407C 1953 - ACAACTTCCCTCAGAATGAA V|658|L V|658|I V|657|L V|657|I TRS120 TRapp Subunit 1289.0 0 0 0 0 -0.002939688774730561 Q04183 0.9539830088615416 0.9574310183525084 0.9539830088615416 0.9574310183525084 0.233465239405632 0.14517343044281006 0.7906239628791809 0.7567408680915833 44.229022669553 40.0 0.0 no 2798 chrIV_1285965 8563 essential YDR407C 1954 - AACAACTTCCCTCAGAATGA V|658|L V|658|I V|657|L V|657|I TRS120 TRapp Subunit 1289.0 0 0 0 0 0.8896318141924968 Q04183 0.9539830088615416 0.9574310183525084 0.9539830088615416 0.9574310183525084 0.233465239405632 0.14517343044281006 0.7906239628791809 0.7567408680915833 44.229022669553 40.0 0.0 no 2799 chrIV_1286144 8565 essential YDR407C 1775 - AAACTTTAATGCATAGTTGT V|598|L V|598|I TRS120 TRapp Subunit 1289.0 0 0 0 0 0.12595656800968913 Q04183 0.9539830088615416 0.9574310183525084 0.08150152862071991 0.4279599189758301 36.785331979210355 25.0 0.0 no 2800 chrIV_1286274r 8568 essential YDR407C 1642 + TAGCATGGCATCCTGACTAC A|549|G A|549|V TRS120 TRapp Subunit 1289.0 0 0 0 0 1.4413365751517189 Q04183 0.9484469890594482 0.9504740238189696 0.4933699667453766 0.6384666562080383 51.176703767324845 50.0 0.0 no 2801 chrIV_1286351 8571 essential YDR407C 1568 - GCTTTCTTTTGTATCCCAAA K|529|N silent|AAG>AAA|K|529 R|528|T R|528|K TRS120 TRapp Subunit 1289.0 0 0 0 0 -0.21247135667067424 Q04183 0.9355990290641784 0.932735025882721 0.955805003643036 0.0 0.016485031694173813 0.3692412078380585 47.68285070655953 35.0 0.0 no 2802 chrIV_1286470 8573 essential YDR407C 1449 - ACTTCAAACCTTGGGAACAT V|490|L V|490|I E|489|Q E|489|K TRS120 TRapp Subunit 1289.0 0 0 0 0 0.5465688704456511 Q04183 0.9539830088615416 0.9574310183525084 0.956179976463318 0.9475290179252625 0.07294680923223495 1.0 0.04655921459197998 0.036895446479320526 43.67536369011657 40.0 0.0 no 2803 chrIV_1286611 8576 essential YDR407C 1308 - AACTCGCAATAAACCACTTG E|442|D silent|GAG>GAA|E|442 E|442|Q E|442|K TRS120 TRapp Subunit 1289.0 0 0 0 0 0.1919919908217222 Q04183 0.94931298494339 0.956179976463318 0.9475290179252625 0.4505684077739716 0.4169377088546753 0.5597232580184937 40.69468952714783 40.0 0.0 no 2804 chrIV_1286727 8580 essential YDR407C 1192 - TACATCAATATTTAATGCTG V|404|L V|404|I D|403|H D|403|N TRS120 TRapp Subunit 1289.0 0 0 0 0 0.32997928639521634 Q04183 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 0.2870365679264069 0.5851781368255615 0.03435678035020828 0.08436785638332367 34.90414687795197 25.0 0.0 no 2805 chrIV_1286791 8581 essential YDR407C 1128 - GCTATAGATATGCTGTTCCT A|383|P A|383|T TRS120 TRapp Subunit 1289.0 0 1 0 0 -0.4720207372285754 Q04183 0.9573720097541808 0.9523990154266356 0.2813720703125 1.0 49.447620713758056 40.0 0.0 no 2806 chrIV_1286887 8585 essential YDR407C 1032 - TCAAAATTGAGCTTCTCCAC E|351|Q E|351|K TRS120 TRapp Subunit 1289.0 0 1 0 0 -0.4799968354698042 Q04183 0.956179976463318 0.9475290179252625 43.62568893462321 40.0 0.0 no 2807 chrIV_1287144 8591 essential YDR407C 775 - ATTCTCAGATGTGGAAAGCG E|264|D silent|GAG>GAA|E|264 E|264|Q E|264|K TRS120 TRapp Subunit 1289.0 0 0 0 0 -0.07779617357665264 Q04183 0.94931298494339 0.956179976463318 0.9475290179252625 1.0 0.1041029617190361 0.08757883310317993 43.882763387446964 45.0 0.0 no 2808 chrIV_1287358 8595 essential YDR407C 561 - GCATTCCCACCAATCGCACC A|194|P A|194|T silent|GGG>GGC|G|192 silent|GGG>GGA|G|192 TRS120 TRapp Subunit 1289.0 0 0 0 0 0.09633796528985243 Q04183 0.9573720097541808 0.9523990154266356 0.07532071322202682 0.6828849911689758 58.572851070194424 60.0 0.0 no 2809 chrIV_1287384 8598 essential YDR407C 535 - CCTCAAAGTAACATGTTTAT L|184|F silent|TTG>TTA|L|184 R|185|T R|185|K TRS120 TRapp Subunit 1289.0 0 1 0 0 0.9619553821138422 Q04183 0.9587849974632264 0.932735025882721 0.955805003643036 0.0 0.0 0.0 39.073888610369295 30.0 0.0 no 2810 chrIV_1287466 8599 essential YDR407C 453 - TCTATGTTTTTCTGCATATC E|158|Q E|158|K TRS120 TRapp Subunit 1289.0 0 0 0 0 0.9075255027018838 Q04183 0.956179976463318 0.9475290179252625 0.1366509199142456 0.0226485338062048 43.089819646742285 30.0 0.0 no 2811 chrIV_1287501 8600 essential YDR407C 418 - TACATTTTCCATCGTATCTA V|146|L V|146|I TRS120 TRapp Subunit 1289.0 0 0 0 0 0.7094897348647047 Q04183 0.9539830088615416 0.9574310183525084 0.6639896631240845 0.6194614171981812 43.76951586255456 30.0 0.0 no 2812 chrIV_1287853 8607 essential YDR407C 66 - TTTCGCGTCCAATGGCCAAT R|28|P R|28|Q silent|ACG>ACC|T|27 silent|ACG>ACA|T|27 TRS120 TRapp Subunit 1289.0 0 0 0 0 -0.002913077607350989 Q04183 0.9099509716033936 0.949662983417511 0.18031840026378632 0.4157830476760864 52.779802952243756 50.0 0.0 no 2813 chrIV_1294706r 8610 essential YDR412W 16 - TCTTGTAAGGATTTGCCTAT R|12|T R|12|K RRP17 Ribosomal RNA Processing 235.0 0 0 0 0 0.19315796124595624 Q04031 0.3217282295227051 1.0 45.696332964859494 35.0 1.0 no 2814 chrIV_1295142 8619 essential YDR412W 449 + TGACTCAACTACTGTTGAAT D|151|E silent|GAC>GAT|D|151 S|152|* S|152|L RRP17 Ribosomal RNA Processing 235.0 0 0 0 0 0.3918093818398988 Q04031 0.3595479726791382 0.17365530133247375 39.97652751368349 35.0 1.0 no 2815 chrIV_1298731r 8624 essential YDR416W 302 - AATCTCGTACACAGCTTTTC D|107|H D|107|N R|106|P R|106|Q SYF1 SYnthetic lethal with cdcForty 859.0 0 0 0 0 0.4061500360599663 Q04048 0.9486550092697144 0.956179976463318 0.9099509716033936 0.949662983417511 0.1546964794397354 0.888935387134552 0.17687654495239258 0.5141033530235289 45.534982526355115 40.0 1.0 no 2816 chrIV_1299262r 8630 essential YDR416W 833 - TATCTAAACCTAGTTTTTCT D|284|H D|284|N SYF1 SYnthetic lethal with cdcForty 859.0 0 0 0 0 0.8965661031307657 Q04048 0.9486550092697144 0.956179976463318 0.2198011726140976 0.16195866465568542 39.76130711464805 25.0 1.0 no 2817 chrIV_1299327r 8632 essential YDR416W 898 - GATCAAAAAAAGCCATTTGT L|305|F silent|TTG>TTA|L|305 SYF1 SYnthetic lethal with cdcForty 859.0 0 0 0 0 0.4266679577900807 Q04048 0.9587849974632264 0.029912140220403668 36.4921408503621 30.0 1.0 no 2818 chrIV_1299492r 8636 essential YDR416W 1063 - TAGCTTTCCCAGAATAAATT K|360|N silent|AAG>AAA|K|360 SYF1 SYnthetic lethal with cdcForty 859.0 0 0 0 0 0.8630638936983035 Q04048 0.9355990290641784 0.37902215123176575 41.30801484079433 30.0 1.0 no 2819 chrIV_1299645r 8637 essential YDR416W 1216 - CATCCACGTTTCCACCAAGT W|411|C W|411|* W|411|S W|411|* SYF1 SYnthetic lethal with cdcForty 859.0 0 0 0 0 -0.2342497848388003 Q04048 0.8858469724655151 0.8858469724655151 0.0 0.0 53.71282594813465 50.0 1.0 no 2820 chrIV_1299740r 8640 essential YDR416W 1311 - CCAGGCGTACCAACTTTTCG G|444|R G|444|S silent|ACG>ACC|T|442 silent|ACG>ACA|T|442 SYF1 SYnthetic lethal with cdcForty 859.0 0 0 0 0 0.7664606520921685 Q04048 0.941340982913971 0.951104998588562 0.6985040903091431 0.16947539150714874 52.35303658526158 55.00000000000001 1.0 no 2821 chrIV_1299866r 8644 essential YDR416W 1437 - TCTTCCAGATCTTCTATATA E|486|Q E|486|K E|485|Q E|485|K SYF1 SYnthetic lethal with cdcForty 859.0 0 0 0 0 0.4746346050844776 Q04048 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.6021567583084106 0.9013118147850036 0.0553525909781456 0.05613953247666359 43.847931873956846 30.0 1.0 no 2822 chrIV_1299895r 8645 essential YDR416W 1466 - ATTCTCTATCAGCCCAGTTT E|495|Q E|495|K R|494|T R|494|K SYF1 SYnthetic lethal with cdcForty 859.0 0 0 0 0 -0.3823929373837404 Q04048 0.956179976463318 0.9475290179252625 0.932735025882721 0.955805003643036 0.0 0.0 0.17341803014278412 1.0 53.22690049673645 40.0 1.0 no 2823 chrIV_1300084 8648 essential YDR416W 1652 + TCTAGAGGCTTACTGCCCAA L|552|V silent|CTA>TTA|L|552 SYF1 SYnthetic lethal with cdcForty 859.0 0 0 0 0 -0.3148945960420111 Q04048 0.9512209892272948 0.4712272882461548 53.76630563251405 50.0 1.0 no 2824 chrIV_1300184r 8650 essential YDR416W 1755 - GCAAAATTTTCTGCCATTGC A|592|P A|592|T SYF1 SYnthetic lethal with cdcForty 859.0 0 0 0 0 1.0596944161603077 Q04048 0.9573720097541808 0.9523990154266356 0.02466085180640221 0.02671157941222191 45.84497274347468 40.0 1.0 no 2825 chrIV_1300119r 8651 essential YDR416W 1690 - TGTCTTATTGAATATTTTAT K|569|N silent|AAG>AAA|K|569 SYF1 SYnthetic lethal with cdcForty 859.0 0 0 0 0 0.11366704519960875 Q04048 0.9355990290641784 0.21097424626350406 33.594347613783725 15.0 1.0 no 2826 chrIV_1300281r 8655 essential YDR416W 1852 - CCATAATTCGTATTGGATTT W|624|S W|624|* SYF1 SYnthetic lethal with cdcForty 859.0 0 0 0 0 0.7639133803346277 Q04048 0.8858469724655151 0.0 41.27248828046419 30.0 1.0 no 2827 chrIV_1322274r 8659 essential YDR427W 72 - TTCTCAAATTGTTCGAATAA E|30|D silent|GAG>GAA|E|30 E|30|Q E|30|K RPN9 Regulatory Particle Non-ATPase 393.0 0 0 0 0 1.5286910776591398 Q04062 0.19657456874847407 0.1149960234761238 0.14239753782749176 1.0343220233917236 -0.36349400877952576 -0.2530339956283569 35.062758202474924 25.0 1.0 no 2828 chrIV_1322356 8661 essential YDR427W 151 + ATGCTAAATCTACACCATTG A|52|G A|52|V RPN9 Regulatory Particle Non-ATPase 393.0 0 1 0 0 -0.2463955582067425 Q04062 0.04680722579360008 0.020684298127889637 0.399509996175766 0.6219559907913208 41.132975558448955 35.0 1.0 no 2829 chrIV_1322567r 8663 essential YDR427W 365 - TCAACAAAATACCATCACCA L|128|F silent|TTG>TTA|L|128 L|127|F silent|TTG>TTA|L|127 RPN9 Regulatory Particle Non-ATPase 393.0 0 0 0 0 0.8069863986851398 Q04062 0.67035973072052 0.015003777109086512 0.7128120064735413 0.10173799842596054 40.6513485032026 35.0 1.0 no 2830 chrIV_1322694r 8665 essential YDR427W 492 - AAGCTGTTTGTTATCCTTAA S|170|T S|170|N RPN9 Regulatory Particle Non-ATPase 393.0 0 0 0 0 0.2029407624679337 Q04062 0.13176465034484866 0.15850931406021118 1.770823955535889 -0.9756699800491332 43.30272912695313 30.0 1.0 no 2831 chrIV_1324675 8668 essential YDR429C 607 - TTCTCTCAAACTATTTTCAT E|209|Q E|209|K R|208|T R|208|K TIF35 Translation Initiation Factor 274.0 0 0 0 0 -0.12432620566038632 Q04067 0.9430189728736876 0.9292250275611876 0.913004994392395 0.9395849704742432 0.5070840120315552 0.6749984622001648 0.07687858492136003 0.3653386831283569 38.98111942882434 25.0 0.0 no 2832 chrIV_1324846 8674 essential YDR429C 436 - GCCTGCCTTCTCTTCACTGG G|152|R G|152|S G|152|A G|152|D TIF35 Translation Initiation Factor 274.0 0 1 0 0 -1.2052308998484729 Q04067 0.9226509928703308 0.9307469725608826 0.9296349883079528 0.9259340167045592 0.5310261249542236 0.8027715682983398 0.8218758106231691 0.6763901114463806 61.68841524155482 60.0 0.0 no 2833 chrIV_1325145 8680 essential YDR429C 137 - TTCTTTCTGCAACAGATTTA R|52|T R|52|K E|51|Q E|51|K TIF35 Translation Initiation Factor 274.0 0 0 0 0 -2.170615271449285 Q04067 0.9002249836921692 0.9185940027236938 0.9594100117683412 0.9491919875144958 0.0 0.0 0.3298881947994232 0.18694572150707245 0.3685399889945984 -0.5048999786376953 0.07406000047922134 0.3125799894332886 41.9628190555045 30.0 0.0 yes 2834 chrIV_1329092r 8691 high_effect YDR432W 312 - CGACCGTGCATGTGTTCACC G|110|A G|110|D G|110|R G|110|S NPL3 Nuclear Protein Localization 414.0 0 0 0 0 -0.17613484235251176 Q01560 0.9901490211486816 0.9780880212783812 0.9727219939231871 0.991388976573944 55.9942625341539 60.0 1.0 no 2835 chrIV_1329116r 8692 high_effect YDR432W 336 - TCTTGACGGTGGTGCATTGG E|119|Q E|119|K R|117|P R|117|H NPL3 Nuclear Protein Localization 414.0 0 0 0 0 -0.03249259055225456 Q01560 0.97645902633667 0.9644089937210084 0.960108995437622 0.9998890161514282 0.3085285425186157 0.4411069452762604 52.73448199760981 55.00000000000001 1.0 no 2836 chrIV_1329119 8693 high_effect YDR432W 336 + CCAATGCACCACCGTCAAGA P|113|R P|113|L H|115|D H|115|Y NPL3 Nuclear Protein Localization 414.0 0 0 0 0 0.2885926171579944 Q01560 0.9753050208091736 0.9834169745445251 0.9914770126342772 0.9916279911994934 52.56362290544632 55.00000000000001 1.0 no 2837 chrIV_1329130r 8695 high_effect YDR432W 350 - TCGAGAGTTCTCCTTCTTGA silent|TCG>TCC|S|123 silent|TCG>TCA|S|123 NPL3 Nuclear Protein Localization 414.0 0 0 0 0 -0.2260872300924349 Q01560 51.15981040851914 45.0 1.0 no 2838 chrIV_1329198r 8699 high_effect YDR432W 418 - ACCAAAGATTTCATTCAACT G|146|R G|146|S G|146|A G|146|D NPL3 Nuclear Protein Localization 414.0 0 0 0 0 0.4019042782215477 Q01560 0.9360229969024658 0.9557530283927916 0.9545140266418456 0.941208004951477 0.4496743381023407 0.8027300238609314 0.6411998867988586 0.4519459903240204 -0.5212600231170654 1.3286199569702148 0.5773199796676636 1.803699970245361 39.45201313664262 30.0 1.0 no 2839 chrIV_1329404r 8701 high_effect YDR432W 624 - TCTTGCCATGAACAACCTTC D|215|H D|215|N W|213|C W|213|* NPL3 Nuclear Protein Localization 414.0 0 1 0 0 -0.5636756091881989 Q01560 0.974511981010437 0.9857460260391236 0.9440850019454956 0.09259390830993652 0.006841748487204313 0.003831578884273768 2.295419931411743 2.6717000007629395 3.1071200370788574 48.20183523049741 45.0 1.0 no 2840 chrIV_1329389 8702 high_effect YDR432W 606 + ACCATGAAAAACTTACCAGA silent|ACC>ACG|T|203 silent|ACC>ACT|T|203 T|203|S T|203|I NPL3 Nuclear Protein Localization 414.0 0 0 0 1 -1.044015897762298 Q01560 0.9513729810714722 0.9485089778900146 0.6888231635093689 0.7458829283714294 0.5679000020027161 -0.7858800292015076 39.46680469825827 35.0 1.0 no 2841 chrIV_1329476 8703 high_effect YDR432W 693 + GTCAATACCAGAGATTTTGA silent|GTC>GTG|V|232 silent|GTC>GTT|V|232 NPL3 Nuclear Protein Localization 414.0 0 0 0 0 -0.03835813897537831 Q01560 42.073094814674846 35.0 1.0 no 2842 chrIV_1329517r 8708 high_effect YDR432W 737 - CGACCAAGATTTCTTCACTA V|252|L V|252|I L|251|F silent|TTG>TTA|L|251 NPL3 Nuclear Protein Localization 414.0 0 0 0 0 0.05240526383313685 Q01560 0.9786369800567628 0.9863060116767884 0.989130973815918 0.2638099193572998 0.10732103139162064 0.0038736707065254454 -1.147860050201416 -0.7988799810409546 3.010900020599365 44.607740111036435 40.0 1.0 no 2843 chrIV_1331473 8715 essential YDR434W 236 + TAACCATTTATTGAATTCTC N|80|K silent|AAC>AAT|N|80 H|81|D H|81|Y GPI17 GlycosylPhosphatidylInositol anchor biosynthesis 534.0 0 0 0 0 -1.4444707969118529 Q04080 0.9439849853515624 0.9473130106925964 0.9489949941635132 0.023268025368452072 0.5860243439674377 1.0 36.88753738281883 25.0 1.0 no 2844 chrIV_1331528r 8716 essential YDR434W 294 - TGCTCAATAGTCTCATTATA E|104|D silent|GAG>GAA|E|104 E|104|Q E|104|K GPI17 GlycosylPhosphatidylInositol anchor biosynthesis 534.0 0 1 0 0 -0.21843927236109406 Q04080 0.94931298494339 0.956179976463318 0.9475290179252625 1.0 0.06683413684368134 0.0725603699684143 41.573039695914304 30.0 1.0 no 2845 chrIV_1331722r 8718 essential YDR434W 488 - TCAAATGCGTCCATTCCAAT L|169|F silent|TTG>TTA|L|169 GPI17 GlycosylPhosphatidylInositol anchor biosynthesis 534.0 0 1 0 0 -0.18606131765537712 Q04080 0.9587849974632264 0.5008465647697449 46.68901328391843 40.0 1.0 no 2846 chrIV_1332120 8724 essential YDR434W 883 + TGGCGTTCATTAATGGCACT A|296|G A|296|V GPI17 GlycosylPhosphatidylInositol anchor biosynthesis 534.0 0 1 0 0 0.42968759091165065 Q04080 0.9484469890594482 0.9504740238189696 0.3704806268215179 0.2834469377994537 49.278809925647685 45.0 1.0 no 2847 chrIV_1332345 8730 essential YDR434W 1108 + TTACCATAGATTCATTCAAA T|371|S T|371|I silent|ACC>ACG|T|371 silent|ACC>ACT|T|371 GPI17 GlycosylPhosphatidylInositol anchor biosynthesis 534.0 0 0 0 0 -0.3311363770934113 Q04080 0.9491789937019348 0.9472420215606691 0.9595500230789183 0.3059314787387848 37.552700358917946 25.0 1.0 no 2848 chrIV_1337427 8731 essential YDR437W 75 + TCCATCTTACCATCATCGCT silent|TCC>TCG|S|26 silent|TCC>TCT|S|26 S|26|C S|26|F 0 0 0 0 0.5126867122926166 Q04082 0.945252001285553 0.9294660091400146 0.009389747865498066 0.004627590533345939 53.36572493756347 45.0 1.0 no 2849 chrIV_1337436r 8732 essential YDR437W 87 - GCAGCCTCACCCAGCGATGA A|36|P A|36|T A|35|P A|35|T 0 0 0 0 -2.1552780527905537 Q04082 0.9573720097541808 0.9523990154266356 0.9573720097541808 0.9523990154266356 0.26050627231597895 0.5334455966949463 0.3290283977985382 0.6713714003562927 61.803074247130674 65.0 1.0 yes 2850 chrIV_1337518r 8735 essential YDR437W 169 - CATCAGCATTATGCTCTCCA silent|CTG>CTC|L|62 silent|CTG>CTA|L|62 M|61|I M|61|I 0 0 0 0 0.07398743176302602 Q04082 0.9553959965705872 0.9553959965705872 0.7210668325424194 0.7210668325424194 52.23402935807457 45.0 1.0 no 2851 chrIV_1337564r 8737 essential YDR437W 215 - TATCTTCATTGTACATCAGA D|78|H D|78|N E|77|Q E|77|K 0 0 0 0 0.8479815486502713 Q04082 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.007636657450348139 0.028828782960772518 0.2238258570432663 0.1927478164434433 41.3613384156385 30.0 1.0 no 2852 chrIV_1356155 8742 high_effect YDR448W 90 + TGCGTGCCCTGCTTTTCACA C|31|W silent|TGC>TGT|C|31 P|33|A P|33|S 0 0 0 0 0.5250063347923618 Q02336 0.9286419749259948 0.9562489986419678 0.9498909711837769 0.0 0.2983817160129547 0.3907426595687866 59.79453381204286 55.00000000000001 1.0 no 2853 chrIV_1356239 8747 high_effect YDR448W 174 + CCCATTCTCTGTCCTGATTG silent|CCC>CCG|P|59 silent|CCC>CCT|P|59 P|59|R P|59|L 0 0 0 0 -0.3150140195330012 Q02336 0.9432820081710817 0.9430609941482544 0.0 0.0 54.85971539562684 50.0 1.0 no 2854 chrIV_1356264r 8748 high_effect YDR448W 202 - AATCAACTGCAATTCTTCAT L|73|F silent|TTG>TTA|L|73 Q|72|H silent|CAG>CAA|Q|72 0 0 0 0 0.0363374383526697 Q02336 0.9587849974632264 0.9570760130882264 0.0 0.0683276355266571 39.92060219617622 30.0 1.0 no 2855 chrIV_1356436 8754 high_effect YDR448W 371 + TGTCCCACAAGATGAATTTT silent|GTC>GTG|V|125 silent|GTC>GTT|V|125 P|126|A P|126|S 0 0 0 0 0.4913268283414924 Q02336 0.9562489986419678 0.9498909711837769 0.25059929490089417 0.7295496463775635 43.73277913634905 35.0 1.0 no 2856 chrIV_1356541r 8764 high_effect YDR448W 479 - GCATAAACCCCTGTACTTCA M|166|I M|166|I 0 0 0 0 0.33601636060356754 Q02336 0.9553959965705872 0.9553959965705872 0.017968889325857162 0.017968889325857162 50.819663769799604 45.0 1.0 no 2857 chrIV_1356612r 8765 high_effect YDR448W 550 - TTCAAAAACCATATCCTTTA E|190|Q E|190|K 0 0 0 0 1.38447928577587 Q02336 0.956179976463318 0.9475290179252625 0.037698358297348016 0.043093793094158166 38.00620172122626 25.0 1.0 no 2858 chrIV_1356705r 8766 high_effect YDR448W 643 - TAGCCTTTTCTTTTCTGCTC R|220|S silent|AGG>AGA|R|220 R|220|T R|220|K 0 0 0 0 0.3916695714796649 Q02336 0.9087679982185364 0.932735025882721 0.955805003643036 0.22123943269252774 0.17340593039989471 1.0 52.38783742684842 40.0 1.0 no 2859 chrIV_1356648r 8768 high_effect YDR448W 586 - AAACTTCAATTCAATGTCTA K|201|N silent|AAG>AAA|K|201 L|200|F silent|TTG>TTA|L|200 0 0 0 0 0.920574390587168 Q02336 0.9355990290641784 0.9587849974632264 0.0 0.13456031680107114 35.5784750454543 25.0 1.0 no 2860 chrIV_1356647r 8769 high_effect YDR448W 585 - AACTTCAATTCAATGTCTAA K|201|N silent|AAG>AAA|K|201 L|200|F silent|TTG>TTA|L|200 0 0 0 0 -0.5842299168650948 Q02336 0.9355990290641784 0.9587849974632264 0.0 0.13456031680107114 35.5784750454543 25.0 1.0 no 2861 chrIV_1357948 8779 essential YDR449C 935 - ACCTTAGTGACTCACTGAAT R|318|T R|318|K R|318|S silent|AGG>AGA|R|318 UTP6 U Three Protein 440.0 0 0 0 0 -0.1661247335477915 Q02354 0.932735025882721 0.955805003643036 0.9087679982185364 0.06988122314214706 1.0 0.06695827841758728 45.34359794827872 40.0 0.0 no 2862 chrIV_1357958 8781 essential YDR449C 925 - CTCACTGAATAGGTAATTCA E|315|Q E|315|K S|314|T S|314|N UTP6 U Three Protein 440.0 0 0 0 0 -0.8436806304316065 Q02354 0.956179976463318 0.9475290179252625 0.9512869715690612 0.9536849856376648 0.05231231078505516 0.04386787861585617 0.4296427667140961 0.4623973369598389 40.17386552259944 35.0 0.0 no 2863 chrIV_1358000 8782 essential YDR449C 883 - ATTCATTTTGGAATCTGAGA M|300|I M|300|I UTP6 U Three Protein 440.0 0 0 0 0 -1.7886269747368764 Q02354 0.9553959965705872 0.9553959965705872 39.82264622776683 30.0 0.0 no 2864 chrIV_1358032r 8784 essential YDR449C 848 + GCATTATATTAATAAGCATA H|284|D H|284|Y UTP6 U Three Protein 440.0 0 0 0 0 0.3321416061026238 Q02354 0.9473130106925964 0.9489949941635132 0.2830021381378174 1.0 34.21648661141245 20.0 0.0 no 2865 chrIV_1358174 8786 essential YDR449C 709 - ATCTTTCATTGAATCACCAG D|243|H D|243|N M|241|I M|241|I UTP6 U Three Protein 440.0 0 0 0 0 1.1827334935562923 Q02354 0.9486550092697144 0.956179976463318 0.9553959965705872 0.9553959965705872 0.113352470099926 0.4415602385997772 1.0 1.0 42.73013820319301 35.0 0.0 no 2866 chrIV_1358346 8788 essential YDR449C 537 - ACATATTCATACCATAGCTT V|186|L V|186|I UTP6 U Three Protein 440.0 0 0 0 0 -1.4732392351276304 Q02354 0.9539830088615416 0.9574310183525084 0.3897923529148102 0.7171739339828491 43.25254616278761 30.0 0.0 no 2867 chrIV_1358461 8790 essential YDR449C 422 - TCCAAATGTCCACATTCGTT W|147|S W|147|* W|147|C W|147|* UTP6 U Three Protein 440.0 0 0 0 0 -2.1280810049265853 Q02354 0.8858469724655151 0.8858469724655151 0.0 0.0 47.82791909016203 40.0 0.0 yes 2868 chrIV_1358747 8793 essential YDR449C 136 - GTCATTTATGCTAGACCCTC D|52|H D|52|N UTP6 U Three Protein 440.0 0 0 0 0 -0.43077527066357857 Q02354 0.9486550092697144 0.956179976463318 0.0 0.0 51.449887127469815 45.0 0.0 no 2869 chrIV_1358763r 8795 essential YDR449C 117 + GAGCATAGATTAAATTCCAG H|41|D H|41|Y UTP6 U Three Protein 440.0 0 0 0 0 0.2628937231050959 Q02354 0.9473130106925964 0.9489949941635132 0.02023959718644619 0.1499161720275879 39.4073022972342 35.0 0.0 no 2870 chrIV_1358844 8796 essential YDR449C 39 - TCCACCAAGTCATCCATTTC silent|GTG>GTC|V|19 silent|GTG>GTA|V|19 E|20|Q E|20|K UTP6 U Three Protein 440.0 0 0 0 0 0.5975393500730033 Q02354 0.956179976463318 0.9475290179252625 0.5946050882339478 1.0 52.01007640642467 45.0 0.0 no 2871 chrIV_1366728 8808 essential YDR454C 80 - CACTAAACCCGAAAGAATCT S|33|T S|33|N GUK1 GUanylate Kinase 187.0 0 0 0 0 -5.963813515634941 P15454 0.8264529705047607 0.6782209873199463 0.003986174240708351 0.0013875423464924095 0.6188240051269531 0.06600800156593323 40.07843022476021 40.0 0.0 yes 2872 chrIV_1383876 8813 essential YDR460W 65 + TTCTCCGGATGTGAAATTTT S|23|C S|23|F P|24|A P|24|S TFB3 Transcription Factor B subunit 3 321.0 0 0 0 0 -0.6049893155683147 Q03290 0.945252001285553 0.9294660091400146 0.9562489986419678 0.9498909711837769 0.0072055328637361535 0.005020249169319868 0.0 0.0 43.457520789469584 35.0 1.0 no 2873 chrIV_1383880r 8814 essential YDR460W 72 - TTCACCAAAAATTTCACATC silent|GTG>GTC|V|30 silent|GTG>GTA|V|30 V|30|L V|30|M TFB3 Transcription Factor B subunit 3 321.0 0 0 0 0 0.014375129422593225 Q03290 0.9539830088615416 0.9587630033493042 0.0633939728140831 0.011914541013538836 37.424459707235826 30.0 1.0 no 2874 chrIV_1383973r 8819 essential YDR460W 165 - ATCTTGTCACACCCTTTATA K|61|N silent|AAG>AAA|K|61 TFB3 Transcription Factor B subunit 3 321.0 0 0 0 0 -0.6162819716169206 Q03290 0.9355990290641784 0.0 48.31147638980798 35.0 1.0 no 2875 chrIV_1384020r 8820 essential YDR460W 212 - CTTCCACATCATCGAATATT E|77|Q E|77|K silent|GTG>GTC|V|76 silent|GTG>GTA|V|76 TFB3 Transcription Factor B subunit 3 321.0 0 0 0 0 0.0036631367949113078 Q03290 0.956179976463318 0.9475290179252625 0.4615004360675812 0.6755337715148926 43.160350949664746 35.0 1.0 no 2876 chrIV_1384214r 8825 essential YDR460W 406 - TTGCTTGTTTAATTCCTCGT K|141|N silent|AAG>AAA|K|141 TFB3 Transcription Factor B subunit 3 321.0 0 0 0 0 0.036836218908974594 Q03290 0.9355990290641784 0.020967323333024982 47.86916944975133 35.0 1.0 no 2877 chrIV_1388928 8829 essential YDR464W 56 + ACTAAGCTCACATAACCAAG L|20|V silent|CTA>TTA|L|20 S|21|R silent|AGC>AGT|S|21 SPP41 Suppressor of PrP4 1435.0 0 0 0 0 1.021496000962984 P38904 0.9512209892272948 0.9417110085487366 0.0 0.07422389090061188 41.27071332740428 40.0 1.0 no 2878 chrIV_1389034r 8831 essential YDR464W 165 - TGGCTGTCATCTGGATGCTT S|61|T S|61|N SPP41 Suppressor of PrP4 1435.0 0 0 0 0 0.2087812767658413 P38904 0.9512869715690612 0.9536849856376648 0.18722613155841827 0.2405213564634323 54.65719442395937 50.0 1.0 no 2879 chrIV_1389305r 8836 essential YDR464W 436 - CCTTTCTGTATTCTCCCGCA R|152|T R|152|K E|151|Q E|151|K SPP41 Suppressor of PrP4 1435.0 0 0 0 0 0.6541386988115543 P38904 0.932735025882721 0.955805003643036 0.956179976463318 0.9475290179252625 58.029774317380024 50.0 1.0 no 2880 chrIV_1389483r 8840 essential YDR464W 614 - TGCTGCTCAACTTATCATTC S|211|T S|211|N S|210|T S|210|N SPP41 Suppressor of PrP4 1435.0 0 0 0 0 -0.09061837703988013 P38904 0.9512869715690612 0.9536849856376648 0.9512869715690612 0.9536849856376648 0.4677519202232361 0.4188609421253204 0.3205181360244751 0.28656527400016785 46.519074339227934 40.0 1.0 no 2881 chrIV_1389482r 8841 essential YDR464W 613 - GCTGCTCAACTTATCATTCG S|211|T S|211|N S|210|T S|210|N SPP41 Suppressor of PrP4 1435.0 0 0 0 0 -0.4579936261249702 P38904 0.9512869715690612 0.9536849856376648 0.9512869715690612 0.9536849856376648 0.4677519202232361 0.4188609421253204 0.3205181360244751 0.28656527400016785 47.672206083500605 45.0 1.0 no 2882 chrIV_1389484r 8842 essential YDR464W 615 - TTGCTGCTCAACTTATCATT S|211|T S|211|N S|210|T S|210|N SPP41 Suppressor of PrP4 1435.0 0 0 0 0 -0.844308637270917 P38904 0.9512869715690612 0.9536849856376648 0.9512869715690612 0.9536849856376648 0.4677519202232361 0.4188609421253204 0.3205181360244751 0.28656527400016785 45.74305378487286 35.0 1.0 no 2883 chrIV_1389865r 8848 essential YDR464W 996 - CCAATCGACTGTTCTTGTGA G|339|R G|339|R silent|TCG>TCC|S|337 silent|TCG>TCA|S|337 SPP41 Suppressor of PrP4 1435.0 0 1 0 0 0.22177957483839866 P38904 0.941340982913971 0.941340982913971 0.4723666906356812 0.4723666906356812 48.05453001625972 45.0 1.0 no 2884 chrIV_1389866 8849 essential YDR464W 994 + CTTCACAAGAACAGTCGATT S|333|* S|333|L Q|334|E Q|334|* SPP41 Suppressor of PrP4 1435.0 0 1 0 0 0.18027727488418194 P38904 0.9298099875450134 0.9590039849281312 0.1913800686597824 0.8035138845443726 41.70434427672581 40.0 1.0 no 2885 chrIV_1390005 8853 essential YDR464W 1133 + AACAAAAAGTAAGACATCCA T|379|R T|379|I SPP41 Suppressor of PrP4 1435.0 0 0 0 0 -0.4595835575177613 P38904 0.9476869702339172 0.9472420215606691 0.5267320871353149 0.1900469958782196 34.37924843892256 30.0 1.0 no 2886 chrIV_1390200 8855 essential YDR464W 1328 + ATCAACGCATACTGCCACAC S|444|* S|444|L T|445|R T|445|M SPP41 Suppressor of PrP4 1435.0 0 0 0 0 -2.5050403667552668 P38904 0.9298099875450134 0.9476869702339172 0.9502379894256592 0.14170262217521667 0.6525938510894775 0.15790250897407532 49.042943822307855 50.0 1.0 yes 2887 chrIV_1390446 8858 essential YDR464W 1574 + GCATGATAACCTTTCTAGGA H|526|D H|526|Y SPP41 Suppressor of PrP4 1435.0 0 0 0 0 -0.34244408934173115 P38904 0.9473130106925964 0.9489949941635132 0.6699153184890747 0.4651606678962708 45.858262431223295 40.0 1.0 no 2888 chrIV_1390483r 8859 essential YDR464W 1614 - TCAGATTTGCTCGAACTTTT E|545|Q E|545|K SPP41 Suppressor of PrP4 1435.0 0 0 0 0 0.35143918911003713 P38904 0.956179976463318 0.9475290179252625 0.4949527978897095 0.8449980020523071 43.7292034789653 35.0 1.0 no 2889 chrIV_1390644 8863 essential YDR464W 1772 + ATACGTCTCTATTGCCAACG Y|592|* silent|TAC>TAT|Y|592 silent|GTC>GTG|V|593 silent|GTC>GTT|V|593 SPP41 Suppressor of PrP4 1435.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.9922209743888504 P38904 46.987795617301224 45.0 1.0 no 2890 chrIV_1390737r 8864 essential YDR464W 1868 - TCCTTTCCTCTCTGGCAGTT R|629|T R|629|K R|629|S silent|AGG>AGA|R|629 SPP41 Suppressor of PrP4 1435.0 0 0 0 0 0.009073165783707815 P38904 0.932735025882721 0.955805003643036 0.9087679982185364 0.04665306583046913 1.0 0.03876867890357971 60.179990392103775 50.0 1.0 no 2891 chrIV_1390885r 8868 essential YDR464W 2016 - TCCGGAGTCCATCTTCTGTA silent|CCG>CCC|P|678 silent|CCG>CCA|P|678 E|679|Q E|679|K SPP41 Suppressor of PrP4 1435.0 0 0 0 0 0.2447048581659416 P38904 0.956179976463318 0.9475290179252625 0.0 0.0 55.93476651521519 50.0 1.0 no 2892 chrIV_1391016 8870 essential YDR464W 2144 + TCCTCTCTTCAACTTTGTAA P|716|R P|716|L P|716|A P|716|S SPP41 Suppressor of PrP4 1435.0 0 0 0 0 -0.05140883940003765 P38904 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 45.78790568128585 35.0 1.0 no 2893 chrIV_1391050r 8871 essential YDR464W 2181 - TTCAGACGATGTCTTGCACT silent|CTG>CTC|L|733 silent|CTG>CTA|L|733 R|732|P R|732|H SPP41 Suppressor of PrP4 1435.0 0 0 0 0 -0.5219429319626078 P38904 0.9099509716033936 0.9570810198783876 0.2745505273342133 0.1321743130683899 48.843353655444325 45.0 1.0 no 2894 chrIV_1391062 8872 essential YDR464W 2190 + CATCGTCTGAATGACATTGA R|732|G R|732|C L|733|V silent|CTG>TTG|L|733 SPP41 Suppressor of PrP4 1435.0 0 0 0 0 0.4383651474655075 P38904 0.8994590044021606 0.8926740288734436 0.9512209892272948 0.38159239292144775 0.056720506399869926 0.1304570436477661 42.25666571897386 40.0 1.0 no 2895 chrIV_1391314r 8876 essential YDR464W 2445 - TTTCTATACTTTTTGATATT R|821|T R|821|K SPP41 Suppressor of PrP4 1435.0 0 0 0 0 0.7982276282036928 P38904 0.932735025882721 0.955805003643036 0.7664363384246826 0.9639014601707458 35.250577073181944 15.0 1.0 no 2896 chrIV_1391350 8877 essential YDR464W 2478 + TCTTTTCGTGTCTCCAAAGA S|827|C S|827|F R|829|G R|829|C SPP41 Suppressor of PrP4 1435.0 0 0 0 0 -0.6163009159511555 P38904 0.945252001285553 0.9294660091400146 0.8994590044021606 0.8926740288734436 0.17862015962600708 0.7034626603126526 0.2340143769979477 0.033207625150680535 47.27798231470611 40.0 1.0 no 2897 chrIV_1391355 8878 essential YDR464W 2483 + TCGTGTCTCCAAAGAAGGTA R|829|G R|829|C silent|GTC>GTG|V|830 silent|GTC>GTT|V|830 SPP41 Suppressor of PrP4 1435.0 0 0 0 0 -0.8503679930377707 P38904 0.8994590044021606 0.8926740288734436 0.2340143769979477 0.033207625150680535 46.543177800634105 45.0 1.0 no 2898 chrIV_1391468r 8883 essential YDR464W 2599 - TTTCCTTGCCTCCTCAGGTG R|872|S silent|AGG>AGA|R|872 R|872|T R|872|K SPP41 Suppressor of PrP4 1435.0 0 0 0 0 0.2999137826133961 P38904 0.9087679982185364 0.932735025882721 0.955805003643036 0.8422736525535583 1.0 0.4317297637462616 60.59139956739061 55.00000000000001 1.0 no 2899 chrIV_1391513 8885 essential YDR464W 2641 + ATGCCAAGTCTACAGTTATT A|882|G A|882|V silent|GCC>GCG|A|882 silent|GCC>GCT|A|882 SPP41 Suppressor of PrP4 1435.0 0 0 0 0 0.3817709767337826 P38904 0.9484469890594482 0.9504740238189696 0.15289387106895447 0.20878005027771 45.68754267779383 35.0 1.0 no 2900 chrIV_1391755r 8890 essential YDR464W 2886 - GCGATTGTAGAATTAGAGTG A|969|P A|969|T SPP41 Suppressor of PrP4 1435.0 0 0 0 0 -1.914889754231616 P38904 0.9573720097541808 0.9523990154266356 0.23969027400016785 0.46549338102340704 40.80980745656473 40.0 1.0 no 2901 chrIV_1391758 8893 essential YDR464W 2886 + CACTCTAATTCTACAATCGC H|963|Q silent|CAC>CAT|H|963 S|964|C S|964|F SPP41 Suppressor of PrP4 1435.0 0 0 0 0 0.3584849714792237 P38904 0.9588389992713928 0.945252001285553 0.9294660091400146 0.5525367856025696 0.052636440843343735 0.06630391627550125 42.21569864609995 40.0 1.0 no 2902 chrIV_1391772 8895 essential YDR464W 2900 + AATCGCTGGGCATACTTTAA I|968|M silent|ATC>ATT|I|968 A|969|G A|969|V SPP41 Suppressor of PrP4 1435.0 0 0 0 0 -0.8197746632100863 P38904 0.9598389863967896 0.9484469890594482 0.9504740238189696 0.06958823651075363 0.3254794180393219 0.2310613542795181 45.257972696179316 40.0 1.0 no 2903 chrIV_1391773 8896 essential YDR464W 2901 + ATCGCTGGGCATACTTTAAA I|968|M silent|ATC>ATT|I|968 A|969|G A|969|V SPP41 Suppressor of PrP4 1435.0 0 0 0 0 -0.8223939916367378 P38904 0.9598389863967896 0.9484469890594482 0.9504740238189696 0.06958823651075363 0.3254794180393219 0.2310613542795181 45.2579726961792 40.0 1.0 no 2904 chrIV_1392014 8901 essential YDR464W 3142 + TAACTGAAGACAAGACAAAT T|1049|S T|1049|I SPP41 Suppressor of PrP4 1435.0 0 0 0 0 0.2514812920829986 P38904 0.9491789937019348 0.9472420215606691 0.9442819356918336 0.2644067704677582 32.081077716639875 30.0 1.0 no 2905 chrIV_1392100r 8903 essential YDR464W 3231 - TCTGTAGCAATTTTCTCACC D|1084|H D|1084|N SPP41 Suppressor of PrP4 1435.0 0 0 0 0 0.3925766719616969 P38904 0.9486550092697144 0.956179976463318 0.11463751643896106 0.4546054899692536 47.831999484338844 40.0 1.0 no 2906 chrIV_1398346r 8907 essential YDR468C 332 + TTCAACACTTAACACCAGCA S|112|* S|112|L T|113|R T|113|I TLG1 T-snare affecting a Late Golgi compartment 224.0 0 0 0 0 -1.3498968715634034 Q03322 0.9298099875450134 0.9476869702339172 0.9472420215606691 0.2936599850654602 0.5230692625045776 0.194158747792244 44.850590883252785 40.0 0.0 no 2907 chrIV_1398376r 8908 essential YDR468C 302 + AACTATTCCTCTAGAAGAGA T|102|S T|102|I TLG1 T-snare affecting a Late Golgi compartment 224.0 0 0 0 0 0.4909508426176398 Q03322 0.9491789937019348 0.9472420215606691 0.7792466878890991 0.2083634585142136 40.83283441391751 35.0 0.0 no 2908 chrIV_1398652r 8911 essential YDR468C 26 + ACAAGTTGTTAAGGACACCA Q|10|E Q|10|* TLG1 T-snare affecting a Late Golgi compartment 224.0 0 0 0 0 -0.7531538948318941 Q03322 0.9590039849281312 0.4260253608226776 -0.30893999338150024 44.05662896211658 40.0 0.0 no 2909 chrIV_1402226 8913 high_effect YHR010W 72 + ATCGTTAAGCCACACGATGA error error 0 0 0 0 -0.5378898802930318 P0C2H6 46.68755217162533 45.0 1.0 no 2910 chrIV_1402258 8915 high_effect YHR010W 104 + TCATCCATTCGGTCACGCTT error error error error 0 0 0 0 0.7461659748623433 P0C2H6 54.62050130444288 50.0 1.0 no 2911 chrIV_1403367r 8919 essential YDR472W 48 - TCATATCCATCAGATTTACC E|23|Q E|23|K G|21|A G|21|E TRS31 TRapp Subunit 283.0 0 0 0 0 -0.10573568435424498 Q03337 0.036315899342298515 0.038438115268945694 0.0 0.0 44.928952443118995 35.0 1.0 no 2912 chrIV_1403403r 8920 essential YDR472W 84 - TCGCTTGTTATCGCTTGCTT S|34|T S|34|N E|35|Q E|35|K TRS31 TRapp Subunit 283.0 0 0 0 0 -0.037895734113224167 Q03337 0.30852606892585754 0.14175932109355927 0.4713894724845886 0.6882781386375427 53.158579679187774 45.0 1.0 no 2913 chrIV_1403446r 8921 essential YDR472W 127 - AGACTCTGAGTATATTCTAG E|48|D silent|GAG>GAA|E|48 E|48|Q E|48|K TRS31 TRapp Subunit 283.0 0 0 0 0 0.03642711967394471 Q03337 0.3500865399837494 0.2226315587759018 0.12771853804588318 40.44095880876785 35.0 1.0 no 2914 chrIV_1403519r 8924 essential YDR472W 200 - GCAACTGTGAAATCATTTCC L|73|F silent|TTG>TTA|L|73 Q|72|H silent|CAG>CAA|Q|72 TRS31 TRapp Subunit 283.0 0 0 0 0 0.5113837971846735 Q03337 0.7109113335609436 0.5422499179840088 0.9340000152587892 1.294399976730347 43.29569022828929 40.0 1.0 no 2915 chrIV_1403709 8925 essential YDR472W 387 + TCAAATGCGTCAAATTCCCC S|130|* S|130|L TRS31 TRapp Subunit 283.0 0 1 0 0 -2.3259328790240072 Q03337 0.2071017175912857 -0.1687999963760376 47.532817882411564 45.0 1.0 yes 2916 chrIV_1404785 8929 essential YDR473C 1050 - TTCAACTTGAATCTTATTTT L|356|F silent|TTG>TTA|L|356 K|355|N silent|AAG>AAA|K|355 PRP3 Pre-mRNA Processing 469.0 0 0 0 0 0.3059138670261837 Q03338 0.023676510900259014 0.0 -0.8157860040664673 0.8914092183113098 35.76311561228954 20.0 0.0 no 2917 chrIV_1404786 8930 essential YDR473C 1049 - TCAACTTGAATCTTATTTTT L|356|F silent|TTG>TTA|L|356 K|355|N silent|AAG>AAA|K|355 PRP3 Pre-mRNA Processing 469.0 0 0 0 0 0.09757008485621736 Q03338 0.023676510900259014 0.0 -0.8157860040664673 0.8914092183113098 35.76311561228954 20.0 0.0 no 2918 chrIV_1404958 8935 essential YDR473C 877 - GTCTTTCACTACTTTTTCCC D|299|H D|299|N silent|GTG>GTC|V|297 silent|GTG>GTA|V|297 PRP3 Pre-mRNA Processing 469.0 0 0 0 0 0.70818228456138 Q03338 0.09819217026233673 0.38203549385070795 51.535820930009784 40.0 0.0 no 2919 chrIV_1404965 8936 essential YDR473C 870 - ACTACTTTTTCCCAGGCAGT V|297|L V|297|M V|296|L V|296|I PRP3 Pre-mRNA Processing 469.0 0 0 0 0 1.0731712012873564 Q03338 0.0 0.0 0.563575029373169 0.8412207961082458 54.64854608010853 45.0 0.0 no 2920 chrIV_1404966 8937 essential YDR473C 869 - CTACTTTTTCCCAGGCAGTT V|296|L V|296|I PRP3 Pre-mRNA Processing 469.0 0 0 0 0 -0.6173064449830885 Q03338 0.563575029373169 0.8412207961082458 54.447197545629756 45.0 0.0 no 2921 chrIV_1405258 8940 essential YDR473C 577 - ATCTTCTGCTAGCTTTTCTT D|199|H D|199|N E|198|Q E|198|K PRP3 Pre-mRNA Processing 469.0 0 0 0 0 0.1845710255755303 Q03338 0.012928799726068974 0.036304231733083725 0.1422250270843506 0.15379826724529266 49.93712099949618 35.0 0.0 no 2922 chrIV_1405262 8941 essential YDR473C 573 - TCTGCTAGCTTTTCTTCGGC E|198|Q E|198|K A|197|P A|197|T PRP3 Pre-mRNA Processing 469.0 0 0 0 0 -0.9174260098346076 Q03338 0.1422250270843506 0.15379826724529266 0.2566443383693695 0.5625832080841064 55.32470379235616 50.0 0.0 no 2923 chrIV_1405415 8943 essential YDR473C 420 - TCCTCATGTAACTCTAAATT E|146|D silent|GAG>GAA|E|146 D|147|H D|147|N PRP3 Pre-mRNA Processing 469.0 0 0 0 0 -0.17516873931899316 Q03338 0.0 0.052848275750875466 0.1744353473186493 40.40976967998381 30.0 0.0 no 2924 chrIV_1405816 8949 essential YDR473C 19 - TTTCGGATTACCTTTTTCAT silent|CCG>CCC|P|12 silent|CCG>CCA|P|12 PRP3 Pre-mRNA Processing 469.0 0 0 0 0 0.5093016086771076 Q03338 44.71752140226106 30.0 0.0 no 2925 chrIV_1405826 8950 essential YDR473C 9 - CCTTTTTCATAGGTATTTCT G|10|R G|10|S PRP3 Pre-mRNA Processing 469.0 0 0 0 0 -0.2426758840231744 Q03338 45.47741679982113 30.0 0.0 no 2926 chrIV_1412534 8956 high_effect YDR477W 161 + CTACCAAATCGTCAAAACGC Y|55|* silent|TAC>TAT|Y|55 Q|56|E Q|56|* SNF1 Sucrose NonFermenting 633.0 0 1 0 0 -0.2766184033663232 P06782 0.9590039849281312 1.0 -0.3247599899768829 41.39207717239145 45.0 1.0 no 2927 chrIV_1413386r 8979 high_effect YDR477W 1016 - CATCAATTTCATCGTTATCT D|345|H D|345|N SNF1 Sucrose NonFermenting 633.0 0 0 0 0 -0.17735954030880574 P06782 0.9486550092697144 0.956179976463318 0.5856953859329224 0.5398557782173157 41.331215250936744 30.0 1.0 no 2928 chrIV_1413387r 8980 high_effect YDR477W 1017 - TCATCAATTTCATCGTTATC D|346|H D|346|N D|345|H D|345|N SNF1 Sucrose NonFermenting 633.0 0 0 0 0 0.2686096023279096 P06782 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.0235582385212183 0.32311487197875977 0.5856953859329224 0.5398557782173157 40.409791065303295 30.0 1.0 no 2929 chrIV_1413436r 8982 high_effect YDR477W 1066 - CTCGTCTTTTTCGTAACCCA E|362|Q E|362|K D|361|H D|361|N SNF1 Sucrose NonFermenting 633.0 0 1 0 0 0.988715401411463 P06782 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.06311345845460893 0.11930151283740995 0.08686591684818268 0.24872227013111115 51.47329199108901 45.0 1.0 no 2930 chrIV_1413542 8983 high_effect YDR477W 1169 + ATCTTTGATCAAGGATATGA S|391|C S|391|F SNF1 Sucrose NonFermenting 633.0 0 0 0 0 0.16555253629398314 P06782 0.945252001285553 0.9294660091400146 0.152336448431015 0.4649318158626557 38.762760039907896 30.0 1.0 no 2931 chrIV_1413670 8986 high_effect YDR477W 1297 + CTGCCAAGCAACACGCAAGA A|434|G A|434|V silent|GCC>GCG|A|434 silent|GCC>GCT|A|434 SNF1 Sucrose NonFermenting 633.0 0 1 0 0 0.13244609272790425 P06782 0.9484469890594482 0.9504740238189696 0.4828282594680786 0.2134108692407608 49.405331709316734 55.00000000000001 1.0 no 2932 chrIV_1413735r 8989 high_effect YDR477W 1365 - TCTTTATACTGATCCATGAA E|462|Q E|462|K SNF1 Sucrose NonFermenting 633.0 0 1 0 0 1.1120302142790708 P06782 0.956179976463318 0.9475290179252625 0.5571231245994568 0.8723425865173341 40.759850258618826 30.0 1.0 no 2933 chrIV_1413736r 8990 high_effect YDR477W 1366 - TTCTTTATACTGATCCATGA E|462|Q E|462|K SNF1 Sucrose NonFermenting 633.0 0 1 0 0 0.4218661345132071 P06782 0.956179976463318 0.9475290179252625 0.5571231245994568 0.8723425865173341 42.46766028333389 30.0 1.0 no 2934 chrIV_1414647r 8993 essential YDR478W 75 - AACGCTCTGGAATTCAGTGT silent|GCG>GCC|A|31 silent|GCG>GCA|A|31 A|31|P A|31|T SNM1 Suppressor of Nuclear Mitochondrial endoribonuclease 198.0 0 0 0 0 -1.4081279040021446 P40993 0.1770336776971817 0.19675271213054654 47.379984835697776 45.0 1.0 no 2935 chrIV_1414880r 8998 essential YDR478W 308 - CACAATTCAAGCAATTAACC C|109|S C|109|Y SNM1 Suppressor of Nuclear Mitochondrial endoribonuclease 198.0 0 0 0 0 -0.2425006840207487 P40993 0.0 0.0 38.41057479571657 35.0 1.0 no 2936 chrIV_1415019r 9003 essential YDR478W 447 - GTACTAGTTTTACTCTTTTG S|155|T S|155|N SNM1 Suppressor of Nuclear Mitochondrial endoribonuclease 198.0 0 0 0 0 0.2173400951446299 P40993 0.4389365613460541 0.4975568950176239 41.25063721167572 30.0 1.0 no 2937 chrIV_1423123r 9008 high_effect YDR484W 363 - ATCATCAAATCATTAACCAT M|127|I M|127|I L|126|F silent|TTG>TTA|L|126 VPS52 Vacuolar Protein Sorting 641.0 0 0 0 0 0.3270838734672295 P39904 0.6952382922172546 0.6952382922172546 0.0 37.319305324268434 25.0 1.0 no 2938 chrIV_1423107 9009 high_effect YDR484W 344 + ACTGGCACATATCTCTCCTA L|116|V silent|CTG>TTG|L|116 A|117|G A|117|V VPS52 Vacuolar Protein Sorting 641.0 0 0 0 0 0.06914338753060584 P39904 0.16012713313102722 0.3778744041919708 0.2901270687580109 52.05180831817603 45.0 1.0 no 2939 chrIV_1423290 9011 high_effect YDR484W 527 + TTCAGCAATGCTAGCACCAA S|177|* S|177|L A|178|G A|178|V VPS52 Vacuolar Protein Sorting 641.0 0 1 0 0 -0.14566217363856573 P39904 49.16906799972857 45.0 1.0 no 2940 chrIV_1423602 9012 high_effect YDR484W 839 + AATCGACTCGCAATTTGCAT I|281|M silent|ATC>ATT|I|281 D|282|E silent|GAC>GAT|D|282 VPS52 Vacuolar Protein Sorting 641.0 0 0 0 0 -0.05399464247342689 P39904 0.025360874831676483 0.5468292832374573 44.52191792150961 40.0 1.0 no 2941 chrIV_1423881r 9015 high_effect YDR484W 1121 - TACAGTTATCTAAAATTGCA C|380|S C|380|Y VPS52 Vacuolar Protein Sorting 641.0 0 0 0 0 0.5040644709948363 P39904 0.42178627848625183 0.07870805263519287 35.851069079208 25.0 1.0 no 2942 chrIV_1428518 9018 essential YDR487C 443 - AATCGACACCGGCCTCAGTG D|154|H D|154|N V|153|L V|153|I RIB3 RIBoflavin biosynthesis 208.0 0 0 0 0 -1.3411608630104084 Q99258 0.9486550092697144 0.956179976463318 0.9539830088615416 0.9574310183525084 0.0008549058111384512 0.0016916573513299227 0.10572854429483414 0.2027590572834015 54.19253759688922 60.0 0.0 no 2943 chrIV_1428549 9020 essential YDR487C 412 - CTGCAAAACACCGCCATCAG L|143|F silent|TTG>TTA|L|143 RIB3 RIBoflavin biosynthesis 208.0 0 0 0 0 0.3552781374998343 Q99258 0.9587849974632264 0.036929912865161896 1.9969199895858765 49.23855491914321 55.00000000000001 0.0 no 2944 chrIV_1428787 9029 essential YDR487C 174 - TCAGCAATGGCATTCGTCAT D|65|H D|65|N A|64|P A|64|T RIB3 RIBoflavin biosynthesis 208.0 0 0 0 0 -0.04224176733837123 Q99258 0.9486550092697144 0.956179976463318 0.9573720097541808 0.9523990154266356 0.007488324772566556 0.13751114904880524 0.09016352146863936 0.40218251943588257 5.027659893035889 -0.7245399951934814 49.67547478497471 45.0 0.0 no 2945 chrIV_1428888 9031 essential YDR487C 73 - ATCACCTTCATTTTCACGAC D|31|H D|31|N G|30|A G|30|D RIB3 RIBoflavin biosynthesis 208.0 0 1 0 0 -5.119608355103223 Q99258 0.9486550092697144 0.956179976463318 0.9499930143356324 0.9446240067481996 0.0 0.0 0.11930561065673828 0.001043309224769473 46.58161816452281 40.0 0.0 yes 2946 chrIV_1428751 9032 essential YDR487C 210 - TTCATGCCTGTTCTCAGTAG M|76|I M|76|I G|75|A G|75|D RIB3 RIBoflavin biosynthesis 208.0 0 0 0 0 0.6845708612483521 Q99258 0.9553959965705872 0.9553959965705872 0.9499930143356324 0.9446240067481996 0.4028911292552948 0.4028911292552948 0.7620155811309814 0.6247108578681946 1.8692799806594849 1.8692799806594849 51.727511860827576 45.0 0.0 no 2947 chrIV_1431069 9034 essential YDR489W 57 + GACTCTACCAAGATCACGCA D|20|E silent|GAC>GAT|D|20 S|21|C S|21|F SLD5 Synthetic Lethality with Dpb11-1 294.0 0 0 0 0 0.03444547171456114 Q03406 1.0 0.04464075714349747 0.05602025240659714 49.050521533012606 50.0 1.0 no 2948 chrIV_1431249r 9036 essential YDR489W 240 - AATCTTTTCATCAACTGATG R|86|T R|86|K SLD5 Synthetic Lethality with Dpb11-1 294.0 0 0 0 0 0.27306344587354603 Q03406 0.10938089340925217 0.4896100163459778 37.85849022217718 30.0 1.0 no 2949 chrIV_1431286r 9037 essential YDR489W 277 - TTCAATTAATTGAGATTGCA E|99|Q E|99|K SLD5 Synthetic Lethality with Dpb11-1 294.0 0 0 0 0 0.910632561681902 Q03406 0.03951098769903183 0.03176846727728844 36.59022748387912 25.0 1.0 no 2950 chrIV_1438860 9041 high_effect YDR495C 2271 - TTCAGGGATGTTTCTTCTGC silent|CTG>CTC|L|763 silent|CTG>CTA|L|763 VPS3 Vacuolar Protein Sorting 1011.0 0 0 0 0 0.7905996538749569 P23643 51.02971073822607 45.0 0.0 no 2951 chrIV_1438974r 9044 high_effect YDR495C 2154 + CTTCTCCTCACTCTTAAACA L|720|V L|720|F silent|CTC>CTG|L|720 silent|CTC>CTT|L|720 VPS3 Vacuolar Protein Sorting 1011.0 0 0 0 0 -0.3828923848747928 P23643 0.14768829941749573 0.1041407585144043 46.561440063160155 40.0 0.0 no 2952 chrIV_1439139 9046 high_effect YDR495C 1992 - TCAATTAGTAACTCTATCCT E|671|Q E|671|K VPS3 Vacuolar Protein Sorting 1011.0 0 0 0 0 -0.05982114687039184 P23643 0.4089064300060272 1.0 41.304884757715456 30.0 0.0 no 2953 chrIV_1439540 9050 high_effect YDR495C 1591 - TTCTATGTGATCGTAATGTA E|537|Q E|537|K VPS3 Vacuolar Protein Sorting 1011.0 0 0 0 0 0.4176268655186065 P23643 0.35302478075027466 0.5400635004043579 39.96412223645956 30.0 0.0 no 2954 chrIV_1440030 9057 high_effect YDR495C 1101 - AACTCAACAATTACATTTCT E|373|D silent|GAG>GAA|E|373 E|373|Q E|373|K VPS3 Vacuolar Protein Sorting 1011.0 0 0 0 0 -0.7438183289603669 P23643 0.4838452041149139 0.3646225035190582 0.3098781704902649 36.13339940076082 25.0 0.0 no 2955 chrIV_1440075r 9058 high_effect YDR495C 1053 + CATCATGGCGACATAATAAA H|353|D H|353|Y VPS3 Vacuolar Protein Sorting 1011.0 0 0 0 0 0.0224592060992874 P23643 0.8756089210510254 0.1389060616493225 38.14996015409912 35.0 0.0 no 2956 chrIV_1440089 9059 high_effect YDR495C 1042 - GCCATGATGATTTACCACTA G|354|R G|354|S G|354|A G|354|D VPS3 Vacuolar Protein Sorting 1011.0 0 0 0 0 0.8673694629120156 P23643 0.0 0.0 0.0 0.0 47.616234832837044 40.0 0.0 no 2957 chrIV_1440458 9067 high_effect YDR495C 673 - ACCTTTAAGTCTAGTTGTGT G|231|R G|231|S G|231|A G|231|D VPS3 Vacuolar Protein Sorting 1011.0 0 0 0 0 -0.2947447230804687 P23643 0.5274199843406677 0.8752514719963074 0.8523323535919191 0.7460491061210632 46.6830982384933 35.0 0.0 no 2958 chrIV_1440459 9068 high_effect YDR495C 672 - CCTTTAAGTCTAGTTGTGTT G|231|R G|231|S VPS3 Vacuolar Protein Sorting 1011.0 0 0 0 0 0.5468342275155125 P23643 0.5274199843406677 0.8752514719963074 46.47657872545676 35.0 0.0 no 2959 chrIV_1440459r 9069 high_effect YDR495C 669 + CCCAACACAACTAGACTTAA silent|CCC>CCG|P|224 silent|CCC>CCT|P|224 P|224|R P|224|L VPS3 Vacuolar Protein Sorting 1011.0 0 0 0 0 0.7039394701618839 P23643 0.0 0.0 42.37533738086887 40.0 0.0 no 2960 chrIV_1440482r 9071 high_effect YDR495C 646 + TTCTCCCAGAATTTGCACCA L|217|V L|217|F silent|CTC>CTG|L|217 silent|CTC>CTT|L|217 VPS3 Vacuolar Protein Sorting 1011.0 0 0 0 0 -0.6871944603613844 P23643 0.0 0.0 52.82656683889593 45.0 0.0 no 2961 chrIV_1440543r 9072 high_effect YDR495C 585 + CTTCTTTTACCTAAAGTAGA L|197|V L|197|F VPS3 Vacuolar Protein Sorting 1011.0 0 0 0 0 1.4244755631420514 P23643 0.05935487896203995 0.03458419442176819 40.104896062491946 30.0 0.0 no 2962 chrIV_1440852 9075 high_effect YDR495C 279 - ACATTATCTTCTGCGCTGCT V|100|L V|100|I VPS3 Vacuolar Protein Sorting 1011.0 0 0 0 0 0.7689404225474191 P23643 0.3436520993709564 0.21328461170196533 52.54055122350496 45.0 0.0 no 2963 chrIV_1440940r 9077 high_effect YDR495C 188 + ACGAGCTGATAAATTTTCCC R|64|G R|64|* A|65|G A|65|V VPS3 Vacuolar Protein Sorting 1011.0 0 0 0 0 -0.5235369108807902 P23643 0.37684622406959534 0.4520508050918579 0.3472251892089844 44.68946931897045 40.0 0.0 no 2964 chrIV_1440954 9078 high_effect YDR495C 177 - TCAGCTCGTACTGTTTCATT D|66|H D|66|N A|65|P A|65|T VPS3 Vacuolar Protein Sorting 1011.0 0 0 0 0 0.7047870894298565 P23643 0.1631791591644287 0.9210920929908752 0.3158914744853973 0.8609993457794191 49.427471443451346 40.0 0.0 no 2965 chrIV_1446166 9085 essential YDR498C 809 - AGACATCTCGTTTCTCTTGA V|276|L V|276|I D|275|H D|275|N SEC20 SECretory 383.0 0 0 0 0 -0.08145570087989151 P28791 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 0.0 0.0 0.01214121375232935 0.16302932798862454 47.57779528894315 40.0 0.0 no 2966 chrIV_1446170 9088 essential YDR498C 805 - ATCTCGTTTCTCTTGATGGG D|275|H D|275|N R|274|P R|274|Q SEC20 SECretory 383.0 0 0 0 0 -0.7394810828988725 P28791 0.9486550092697144 0.956179976463318 0.9099509716033936 0.949662983417511 0.01214121375232935 0.16302932798862454 0.0 0.0 49.41406494725936 45.0 0.0 no 2967 chrIV_1446415r 9090 essential YDR498C 557 + AAGCTTAACGTCCACATCGA S|187|R silent|AGC>AGT|S|187 SEC20 SECretory 383.0 0 0 0 0 0.21112217484903445 P28791 0.9417110085487366 0.5175248980522156 46.76024148013561 45.0 0.0 no 2968 chrIV_1446517 9092 essential YDR498C 458 - TCCAAGCTAAGTCACGTTTG W|159|S W|159|* W|159|C W|159|* SEC20 SECretory 383.0 0 0 0 0 0.07958502642571746 P28791 0.8858469724655151 0.8858469724655151 0.6145027279853821 0.12341728061437607 46.8703656488795 45.0 0.0 no 2969 chrIV_1446518r 9093 essential YDR498C 454 + ACCACAAACGTGACTTAGCT H|153|D H|153|Y H|152|Q silent|CAC>CAT|H|152 SEC20 SECretory 383.0 0 0 0 0 0.4259119705004784 P28791 0.9473130106925964 0.9489949941635132 0.9588389992713928 0.1147814467549324 0.5073698163032532 0.5964306592941284 46.327314486236794 45.0 0.0 no 2970 chrIV_1446833 9096 essential YDR498C 142 - TTCTTCATCATTGTGTTCGT E|54|Q E|54|K E|53|Q E|53|K SEC20 SECretory 383.0 0 0 0 0 0.1214097611531676 P28791 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 47.68637359261015 35.0 0.0 no 2971 chrIV_1446893 9097 essential YDR498C 82 - TTCTCCGCTTTCTTTTCTGC E|34|Q E|34|K G|33|A G|33|E SEC20 SECretory 383.0 0 0 0 0 -0.19327896308141904 P28791 0.956179976463318 0.9475290179252625 0.9499930143356324 0.9438679814338684 54.96855086181347 45.0 0.0 no 2972 chrIV_1446949 9098 essential YDR498C 26 - ATGCATCTTGCAAAACTTCC A|15|P A|15|T D|14|H D|14|N SEC20 SECretory 383.0 0 0 0 0 -1.339708185640032 P28791 0.9573720097541808 0.9523990154266356 0.9486550092697144 0.956179976463318 0.14856640994548798 0.234780415892601 0.07624321430921555 0.8821045756340027 44.969277952307436 40.0 0.0 no 2973 chrIV_1447981r 9102 essential YDR499W 154 - ACTCTGTTTATTGTTTAATG Q|57|H silent|CAG>CAA|Q|57 S|58|T S|58|N LCD1 Lethal, Checkpoint-defective, DNA damage sensitive 747.0 0 0 0 0 0.4936047149380526 Q04377 0.12347980588674545 0.7959011793136597 0.800152063369751 37.6884066765831 25.0 1.0 no 2974 chrIV_1448141 9103 essential YDR499W 311 + AGTCAAGCATCTTCAAGAGT silent|GTC>GTG|V|105 silent|GTC>GTT|V|105 LCD1 Lethal, Checkpoint-defective, DNA damage sensitive 747.0 0 0 0 0 0.5624508156613367 Q04377 45.355958714896076 40.0 1.0 no 2975 chrIV_1448075 9104 essential YDR499W 245 + AAACTTTTTGAACATTGAAA N|83|K silent|AAC>AAT|N|83 LCD1 Lethal, Checkpoint-defective, DNA damage sensitive 747.0 0 0 0 0 1.239189962711998 Q04377 1.0 30.97393471166214 20.0 1.0 no 2976 chrIV_1448573r 9110 essential YDR499W 746 - AAACTATGGACTTCCCTATG V|255|L V|255|I LCD1 Lethal, Checkpoint-defective, DNA damage sensitive 747.0 0 0 0 0 0.4401157498212482 Q04377 0.420913964509964 0.9158979058265686 43.9837539104426 40.0 1.0 no 2977 chrIV_1448694r 9115 essential YDR499W 867 - ACAGCTAATTTCGATTCATT V|296|L V|296|I A|295|P A|295|T LCD1 Lethal, Checkpoint-defective, DNA damage sensitive 747.0 0 0 0 0 0.43167935731275 Q04377 0.04107504338026047 0.2203439176082611 0.019989222288131717 0.02026142925024033 41.23815539319651 30.0 1.0 no 2978 chrIV_1448847r 9117 essential YDR499W 1020 - TTCATATTTGATTCATGTAT M|346|I M|346|I LCD1 Lethal, Checkpoint-defective, DNA damage sensitive 747.0 0 0 0 0 0.7377740547619909 Q04377 0.32588568329811096 0.32588568329811096 37.12085059494325 20.0 1.0 no 2979 chrIV_1448768 9118 essential YDR499W 938 + CACTCATAATTTAGCACTGA T|314|S T|314|I H|315|D H|315|Y LCD1 Lethal, Checkpoint-defective, DNA damage sensitive 747.0 0 0 0 0 0.2190824802718212 Q04377 0.014198794960975647 0.06450958549976349 0.206969290971756 1.0 41.491309036269506 35.0 1.0 no 2980 chrIV_1449113 9123 essential YDR499W 1283 + CACTAGTATAATATTAAATA T|429|S T|429|I LCD1 Lethal, Checkpoint-defective, DNA damage sensitive 747.0 0 0 0 0 1.4691062476455097 Q04377 1.0 0.008006078191101551 28.500248613157396 15.0 1.0 no 2981 chrIV_1449142r 9124 essential YDR499W 1315 - TATCAAGGATTTCAGATCTG L|444|F silent|TTG>TTA|L|444 LCD1 Lethal, Checkpoint-defective, DNA damage sensitive 747.0 0 0 0 0 0.1495548543832494 Q04377 0.39827576279640203 39.83034084297964 35.0 1.0 no 2982 chrIV_1449157 9125 essential YDR499W 1327 + CCTTGATAAGCGGTAGTTGG silent|TCC>TCG|S|443 silent|TCC>TCT|S|443 LCD1 Lethal, Checkpoint-defective, DNA damage sensitive 747.0 0 0 0 0 -1.140234366828134 Q04377 48.75959702330079 50.0 1.0 no 2983 chrIV_1449157r 9126 essential YDR499W 1330 - CCACCAACTACCGCTTATCA W|449|C W|449|* W|450|S W|450|* LCD1 Lethal, Checkpoint-defective, DNA damage sensitive 747.0 0 0 0 0 -0.23614755682441724 Q04377 0.0 0.0 52.38300163173227 50.0 1.0 no 2984 chrIV_1449305r 9128 essential YDR499W 1478 - ATTCATTATCACCTATATTT E|499|Q E|499|K LCD1 Lethal, Checkpoint-defective, DNA damage sensitive 747.0 0 0 0 0 -0.11297344216984012 Q04377 0.579511284828186 0.7861495614051819 39.184087273732594 20.0 1.0 no 2985 chrIV_1449377r 9130 essential YDR499W 1550 - CCTCTTTAGAAATTACCCTT E|523|Q E|523|K E|523|D silent|GAG>GAA|E|523 LCD1 Lethal, Checkpoint-defective, DNA damage sensitive 747.0 0 0 0 0 -0.3065479492816942 Q04377 0.049357041716575616 0.03950253501534462 1.0 45.741919163751966 35.0 1.0 no 2986 chrIV_1449378r 9131 essential YDR499W 1551 - TCCTCTTTAGAAATTACCCT E|523|D silent|GAG>GAA|E|523 D|524|H D|524|N LCD1 Lethal, Checkpoint-defective, DNA damage sensitive 747.0 0 0 0 0 -1.59374773724022 Q04377 1.0 0.013578797690570354 0.1982344090938568 46.460221077730466 35.0 1.0 no 2987 chrIV_1449431r 9135 essential YDR499W 1604 - CCATCTTGTAACCTATTATA M|541|I M|541|I K|540|N silent|AAG>AAA|K|540 LCD1 Lethal, Checkpoint-defective, DNA damage sensitive 747.0 0 0 0 0 0.21106986994975407 Q04377 0.12934733927249908 0.12934733927249908 0.38847288489341736 42.62647847642779 30.0 1.0 no 2988 chrIV_1449432r 9136 essential YDR499W 1605 - TCCATCTTGTAACCTATTAT M|541|I M|541|I E|542|Q E|542|K LCD1 Lethal, Checkpoint-defective, DNA damage sensitive 747.0 0 0 0 0 -0.1997090722180456 Q04377 0.12934733927249908 0.12934733927249908 0.0 0.0 44.12642902048992 30.0 1.0 no 2989 chrIV_1469469 9138 essential YDR510W 69 + ATCAATTTAAAGGTGTCCGA I|24|M silent|ATC>ATT|I|24 SMT3 Suppressor of Mif Two 101.0 0 1 0 0 -0.09388969473014903 Q12306 0.9598389863967896 0.06115320697426796 1.7782000303268433 41.83139606717504 35.0 1.0 no 2990 chrIV_1469529r 9141 essential YDR510W 132 - GCTTCCATCAGCCTTCTTAA A|51|P A|51|T E|50|Q E|50|K SMT3 Suppressor of Mif Two 101.0 0 1 0 0 -1.6744003246741728 Q12306 0.9573720097541808 0.9523990154266356 0.956179976463318 0.9475290179252625 0.0021859204862266783 0.035231798887252815 0.10986336320638657 1.0 5.002600193023682 2.1816000938415527 -0.25679999589920044 0.2108000069856644 2.2733399868011475 1.7577400207519531 54.26269344818701 45.0 1.0 no 2991 chrIV_1491160 9145 essential YDR527W 66 + ACTCTTAGTACCAACAACTG L|24|V L|24|F T|23|S T|23|I RBA50 RNA polymerase II (B) Associated protein 439.0 0 0 0 0 -0.15422118494532505 Q04418 0.5080645680427551 0.7219133377075195 0.7796739339828491 0.16777478158473969 42.656906027712644 40.0 1.0 no 2992 chrIV_1491209r 9148 essential YDR527W 118 - CTTCCAAGATGATATTTTCT W|45|C W|45|* W|45|S W|45|* RBA50 RNA polymerase II (B) Associated protein 439.0 0 0 0 0 -0.2836540369880043 Q04418 0.011774824932217598 0.14445458352565765 41.39830402017635 30.0 1.0 no 2993 chrIV_1491587r 9158 essential YDR527W 496 - TAACATAGGCCTAATTTCTA M|171|I M|171|I RBA50 RNA polymerase II (B) Associated protein 439.0 0 0 0 0 0.09033235319476593 Q04418 0.4069175720214844 0.4069175720214844 40.90788409898073 30.0 1.0 no 2994 chrIV_1491702 9160 essential YDR527W 608 + CGCACCCTTAGATTTCCAGA A|204|G A|204|V P|205|A P|205|S RBA50 RNA polymerase II (B) Associated protein 439.0 0 0 0 0 0.4028777998099488 Q04418 0.07083788514137268 0.3145065903663635 0.42269787192344666 0.11640454083681108 53.81701145802509 50.0 1.0 no 2995 chrIV_1491867r 9162 essential YDR527W 776 - CGACCTCTTTGGGCAAATCA V|265|L V|265|I E|264|D silent|GAG>GAA|E|264 RBA50 RNA polymerase II (B) Associated protein 439.0 0 0 0 0 0.17891511031799187 Q04418 0.302603542804718 0.5033646821975708 0.4546321034431458 49.7295256620929 50.0 1.0 no 2996 chrIV_1498332 9168 essential YDR531W 100 + TCTCGCCTATACACAGTAAC S|35|W S|35|L F|34|L silent|TTC>TTT|F|34 CAB1 Coenzyme A Biosynthesis 367.0 0 0 0 0 -0.5489654323456821 Q04430 0.9288619756698608 0.9298099875450134 0.9387490153312684 0.0723206102848053 0.2532462775707245 0.00617967639118433 -2.7709999084472656 46.90150892523923 45.0 1.0 no 2997 chrIV_1498479r 9172 essential YDR531W 250 - CAACAAATCATAAAACTTGA L|89|F silent|TTG>TTA|L|89 CAB1 Coenzyme A Biosynthesis 367.0 0 0 0 0 -0.5065973773148252 Q04430 0.9587849974632264 0.1749504953622818 0.04800000041723251 30.75077017160328 25.0 1.0 no 2998 chrIV_1498514r 9173 essential YDR531W 285 - CTCGATATACCTTTTATTTG silent|TCG>TCC|S|101 silent|TCG>TCA|S|101 CAB1 Coenzyme A Biosynthesis 367.0 0 0 0 0 0.2972541475005592 Q04430 40.3172106117699 30.0 1.0 no 2999 chrIV_1498679 9178 essential YDR531W 447 + CCATACCTTCTAGTCAATAT P|150|R P|150|L Y|151|* silent|TAC>TAT|Y|151 CAB1 Coenzyme A Biosynthesis 367.0 0 0 0 0 -1.7130913800596193 Q04430 0.9432820081710817 0.9430609941482544 0.0 0.0 45.243306271348104 35.0 1.0 no 3000 chrIV_1498684r 9181 essential YDR531W 455 - CCGACCCTATATTGACTAGA silent|TCG>TCC|S|158 silent|TCG>TCA|S|158 silent|GGG>GGC|G|157 silent|GGG>GGA|G|157 CAB1 Coenzyme A Biosynthesis 367.0 0 0 0 0 -0.4281399701910221 Q04430 48.497497344495116 45.0 1.0 no 3001 chrIV_1498871 9190 essential YDR531W 639 + ATGCTAGTTGGAGATATTTA L|215|V silent|CTA>TTA|L|215 CAB1 Coenzyme A Biosynthesis 367.0 0 0 0 0 0.13861378761572554 Q04430 0.9512209892272948 0.06002005934715271 1.9101999998092647 41.073330612419745 30.0 1.0 no 3002 chrIV_1498859 9191 essential YDR531W 627 + TCTAGCGTTGATATGCTAGT S|210|C S|210|F S|211|R silent|AGC>AGT|S|211 CAB1 Coenzyme A Biosynthesis 367.0 0 0 0 0 0.3710350879800631 Q04430 0.945252001285553 0.9294660091400146 0.9417110085487366 0.01387014053761959 0.012925416231155396 0.336984783411026 47.503582051909454 40.0 1.0 no 3003 chrIV_1499996 9193 high_effect YDR532C 538 - ACAATTTTCAATATCACCAG C|186|S C|186|Y KRE28 385.0 0 0 0 0 1.0444049047860673 Q04431 0.9421560168266296 0.9290120005607604 0.0 0.0 38.66303310198822 30.0 0.0 no 3004 chrIV_1500151 9196 high_effect YDR532C 383 - TTTCATTAAGTTTTACAAAT E|134|Q E|134|K KRE28 385.0 0 0 0 0 0.3277278089183182 Q04431 0.956179976463318 0.9475290179252625 0.4542962312698364 0.9460539221763612 32.02332291969424 15.0 0.0 no 3005 chrIV_1500152 9197 high_effect YDR532C 382 - TTCATTAAGTTTTACAAATT E|134|Q E|134|K KRE28 385.0 0 0 0 0 0.5679182478230967 Q04431 0.956179976463318 0.9475290179252625 0.4542962312698364 0.9460539221763612 32.02332291969424 15.0 0.0 no 3006 chrIV_1500153 9198 high_effect YDR532C 381 - TCATTAAGTTTTACAAATTG E|134|Q E|134|K KRE28 385.0 0 0 0 0 1.0753624786782887 Q04431 0.956179976463318 0.9475290179252625 0.4542962312698364 0.9460539221763612 31.86732515617888 20.0 0.0 no 3007 chrIV_1500224r 9201 high_effect YDR532C 307 + AGACATTGGACTATTTCTTC T|104|R T|104|I KRE28 385.0 0 0 0 0 -0.32955732878256594 Q04431 0.9476869702339172 0.9472420215606691 0.034392770379781716 0.0283934623003006 42.263600282366845 35.0 0.0 no 3008 chrIV_1500368r 9203 high_effect YDR532C 163 + ACAAGTTTGTGAATCCTCTT N|55|K silent|AAC>AAT|N|55 KRE28 385.0 0 0 0 0 1.049780978895285 Q04431 0.9439849853515624 0.11081745475530624 44.47285507547701 35.0 0.0 no 3009 chrIV_1500354 9204 high_effect YDR532C 180 - AAGCTCTCATCGTTCCTAAG S|66|T S|66|N E|65|D silent|GAG>GAA|E|65 KRE28 385.0 0 0 0 0 0.1904654368188889 Q04431 0.9512869715690612 0.9536849856376648 0.94931298494339 0.5708265900611877 0.7567545771598816 0.6189380288124084 47.99896002327341 45.0 0.0 no 3010 chrIV_1500446r 9205 high_effect YDR532C 85 + TGCTAAATAACCAAGAACTA L|30|V silent|CTA>TTA|L|30 KRE28 385.0 0 0 0 0 -0.1108213054985245 Q04431 0.9512209892272948 0.0 35.68128291139442 30.0 0.0 no 3011 chrIV_1500395 9206 high_effect YDR532C 139 - TTCATTTATTGCCAGAATGC E|53|Q E|53|K KRE28 385.0 0 0 0 0 -0.8923300067979403 Q04431 0.956179976463318 0.9475290179252625 1.0 0.8598747849464417 44.20182760884131 35.0 0.0 no 3012 chrV_43329 9207 essential YEL058W 77 + TACGGCCGGATTCAGAACGC T|27|R T|27|M A|28|G A|28|V PCM1 PhosphoaCetylglucosamine Mutase 557.0 0 0 0 0 -5.8640567240282975 P38628 0.9476869702339172 0.9502379894256592 0.9484469890594482 0.9504740238189696 0.0 0.0 0.0 0.0 51.82982392282918 60.0 1.0 yes 3013 chrV_43352r 9208 essential YEL058W 103 - CATCACCGTATCCAAATTCT silent|GTG>GTC|V|40 silent|GTG>GTA|V|40 V|40|L V|40|M PCM1 PhosphoaCetylglucosamine Mutase 557.0 0 0 0 0 -0.2392647402538147 P38628 0.9539830088615416 0.9587630033493042 0.023812223225831985 0.005931111518293619 46.34781321470104 40.0 1.0 no 3014 chrV_43413 9214 essential YEL058W 161 + GCTTCAGGGTCAGTATGTGG L|55|V L|55|F Q|56|E Q|56|* PCM1 PhosphoaCetylglucosamine Mutase 557.0 0 0 0 0 -0.99521106268377 P38628 0.9512209892272948 0.9587849974632264 0.9590039849281312 0.2744063138961792 0.3541386425495148 0.7496580481529236 55.023411253940886 55.00000000000001 1.0 no 3015 chrV_43500 9224 essential YEL058W 248 + ATCGATGCTTTTGGCCACAT S|84|W S|84|L PCM1 PhosphoaCetylglucosamine Mutase 557.0 0 0 0 0 0.7937296355669171 P38628 0.9288619756698608 0.9298099875450134 0.002968121552839875 0.0146675119176507 51.613914910872495 45.0 1.0 no 3016 chrV_43553r 9225 essential YEL058W 304 - TTCAAAATTAGTGGCAAAAG E|108|Q E|108|K PCM1 PhosphoaCetylglucosamine Mutase 557.0 0 0 0 0 0.3909844022187393 P38628 0.956179976463318 0.9475290179252625 0.3326522409915924 0.10444562137126924 33.45205701492165 30.0 1.0 no 3017 chrV_43775 9234 essential YEL058W 523 + ACATTACTGATTTGTCCAAC Y|175|* silent|TAC>TAT|Y|175 T|177|S T|177|I PCM1 PhosphoaCetylglucosamine Mutase 557.0 0 0 0 0 0.47726647342104495 P38628 0.9491789937019348 0.9472420215606691 0.03927916288375855 0.10067001730203627 42.27681264429913 35.0 1.0 no 3018 chrV_43778 9236 essential YEL058W 526 + TTACTGATTTGTCCAACAGG T|177|S T|177|I PCM1 PhosphoaCetylglucosamine Mutase 557.0 0 0 0 0 0.04257168406422263 P38628 0.9491789937019348 0.9472420215606691 0.03927916288375855 0.10067001730203627 44.27936538879465 40.0 1.0 no 3019 chrV_43790r 9238 essential YEL058W 541 - TCCTTCCAGTTTCCGCCTGT G|187|R G|187|R G|187|A G|187|E PCM1 PhosphoaCetylglucosamine Mutase 557.0 0 0 0 0 0.17416881272199222 P38628 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.4427485466003418 0.4427485466003418 0.6284466981887817 0.4488303959369659 63.41582692065987 55.00000000000001 1.0 no 3020 chrV_43883r 9242 essential YEL058W 634 - CCTCTTCTCCAGCTGATACG K|217|N silent|AAG>AAA|K|217 R|218|T R|218|K PCM1 PhosphoaCetylglucosamine Mutase 557.0 0 0 0 0 0.06994740842565622 P38628 0.9355990290641784 0.932735025882721 0.955805003643036 0.06295493245124817 0.470746248960495 1.0 54.70303225243259 55.00000000000001 1.0 no 3021 chrV_43976r 9247 essential YEL058W 727 - TGGCACGTCCCAATCTTCGG silent|GTG>GTC|V|248 silent|GTG>GTA|V|248 V|248|L V|248|M PCM1 PhosphoaCetylglucosamine Mutase 557.0 0 0 0 0 -1.6736729836242847 P38628 0.9539830088615416 0.9587630033493042 0.31873196363449097 0.10565035790205002 56.08641362410975 60.0 1.0 no 3022 chrV_44030r 9249 essential YEL058W 781 - ATTCAACAGTTCTGGAACAT L|266|F silent|TTG>TTA|L|266 silent|CTG>CTC|L|265 silent|CTG>CTA|L|265 PCM1 PhosphoaCetylglucosamine Mutase 557.0 0 0 0 0 -4.308323618085458 P38628 0.9587849974632264 0.0 41.498046623324505 35.0 1.0 yes 3023 chrV_44080 9250 essential YEL058W 828 + ACTAACCAGAGATTACCCAA T|277|S T|277|I N|278|K silent|AAC>AAT|N|278 PCM1 PhosphoaCetylglucosamine Mutase 557.0 0 1 0 0 0.7537357433446449 P38628 0.9491789937019348 0.9472420215606691 0.9439849853515624 0.31185510754585266 0.09508812427520752 1.0 45.144410674554656 40.0 1.0 no 3024 chrV_44138r 9253 essential YEL058W 889 - CCTGTCTGCGTCACCATCAA R|303|T R|303|K D|302|H D|302|N PCM1 PhosphoaCetylglucosamine Mutase 557.0 0 1 0 0 -3.6996926571340434 P38628 0.932735025882721 0.955805003643036 0.9486550092697144 0.956179976463318 0.0 0.0 0.0 0.0 56.01691767150618 55.00000000000001 1.0 yes 3025 chrV_44188 9255 essential YEL058W 936 + TCAAAATTTCATTTGTTGGA S|313|* S|313|L PCM1 PhosphoaCetylglucosamine Mutase 557.0 0 0 0 0 0.1895602605151187 P38628 0.9298099875450134 0.2404659688472748 36.86830487154248 25.0 1.0 no 3026 chrV_44356 9256 essential YEL058W 1104 + CCCGTGTCTTGCACTAAGAC silent|CCC>CCG|P|369 silent|CCC>CCT|P|369 P|369|R P|369|L PCM1 PhosphoaCetylglucosamine Mutase 557.0 0 0 0 0 0.08596440487984111 P38628 0.9432820081710817 0.9430609941482544 0.016106592491269108 0.006061757914721966 52.90072509163797 55.00000000000001 1.0 no 3027 chrV_44296 9257 essential YEL058W 1044 + GTGCAAACTGCCTATGCAAA Q|350|E Q|350|* PCM1 PhosphoaCetylglucosamine Mutase 557.0 0 0 0 0 -0.22647668024241235 P38628 0.9590039849281312 0.0 46.43493157929447 45.0 1.0 no 3028 chrV_49422 9263 essential YEL055C 2098 - TTCTTCTCCTTCGAATAGCT E|706|Q E|706|K E|705|Q E|705|K POL5 POLymerase 1022.0 0 0 0 0 -0.0718919538090863 P39985 0.07782255113124847 0.07273935526609421 0.4653062522411346 0.6622476577758789 49.245845347513686 40.0 0.0 no 3029 chrV_49550 9264 essential YEL055C 1970 - TCCTGAGTAAGGCCTTCTTT R|663|T R|663|K R|663|S silent|AGG>AGA|R|663 POL5 POLymerase 1022.0 0 0 0 0 -0.8753190983856847 P39985 0.16963574290275574 1.0 0.030467817559838295 53.28978035678433 45.0 0.0 no 3030 chrV_49562r 9266 essential YEL055C 1955 + ATCACTTTTAGCCCAAAAGA S|653|* S|653|L L|654|V L|654|F POL5 POLymerase 1022.0 0 0 0 0 -1.683538096390227 P39985 0.013669544830918312 0.018209295347332958 0.017295600846409798 43.50162916972994 35.0 0.0 no 3031 chrV_49647 9271 essential YEL055C 1873 - TTCGATCACAGAAATAGAAT E|631|Q E|631|K silent|GTG>GTC|V|629 silent|GTG>GTA|V|629 POL5 POLymerase 1022.0 0 0 0 0 -1.0303859220588991 P39985 0.4912606477737427 0.16168223321437836 35.10157333242773 30.0 0.0 no 3032 chrV_49721r 9272 essential YEL055C 1796 + ATCAAGAACTGCTCAATCTT S|600|* S|600|L POL5 POLymerase 1022.0 0 0 0 0 -0.3184246266451131 P39985 0.13283754885196686 41.349189288676094 35.0 0.0 no 3033 chrV_49722r 9273 essential YEL055C 1795 + GATCAAGAACTGCTCAATCT S|600|* S|600|L POL5 POLymerase 1022.0 0 0 0 0 -0.2427480132605108 P39985 0.13283754885196686 42.289891518793134 40.0 0.0 no 3034 chrV_49949r 9276 essential YEL055C 1568 + ACAGCTACACGAATTAGCCA Q|524|E Q|524|* L|525|V silent|CTA>TTA|L|525 POL5 POLymerase 1022.0 0 0 0 0 -1.68075601835625 P39985 1.0 0.7114887833595276 47.49334149863722 45.0 0.0 no 3035 chrV_50242 9278 essential YEL055C 1278 - TCAAAGTTTATGGAACCGTG D|433|H D|433|N POL5 POLymerase 1022.0 0 0 0 0 -2.8886427794728564 P39985 0.0 0.0 41.38411248559015 40.0 0.0 yes 3036 chrV_50313 9280 essential YEL055C 1207 - TTCTTCACAAGCCTTCACTA E|409|Q E|409|K E|408|Q E|408|K POL5 POLymerase 1022.0 0 0 0 0 -0.632100851953939 P39985 0.5160650610923767 0.9932454228401184 0.1576988846063614 0.15250898897647858 48.85343322078165 40.0 0.0 no 3037 chrV_50431r 9282 essential YEL055C 1086 + GCAGTTCCTGGCTCGTACAT A|363|G A|363|V P|365|A P|365|S POL5 POLymerase 1022.0 0 0 0 0 0.010640121926184631 P39985 0.0976519137620926 1.0 0.17444440722465515 0.4532165229320526 57.99974387464375 55.00000000000001 0.0 no 3038 chrV_50663 9286 essential YEL055C 857 - TCCAAACAAAATGCAGCCTA W|292|S W|292|* W|292|C W|292|* POL5 POLymerase 1022.0 0 0 0 0 -2.23791704096857 P39985 0.0 0.0 43.44775421452482 40.0 0.0 yes 3039 chrV_50728r 9287 essential YEL055C 789 + TCTGTAATTCCGGATGCCAA S|264|C S|264|F POL5 POLymerase 1022.0 0 0 0 0 -0.24647052225376864 P39985 0.053782247006893165 0.06593543291091919 49.3389656718806 45.0 0.0 no 3040 chrV_50757 9289 essential YEL055C 763 - TCTCAATACTTTTGTTAAAA L|260|F silent|TTG>TTA|L|260 R|261|T R|261|K POL5 POLymerase 1022.0 0 0 0 0 0.23304841666494786 P39985 0.022190550342202187 0.1917870044708252 1.0 33.35705958917879 20.0 0.0 no 3041 chrV_51041r 9293 essential YEL055C 476 + CACGGAACAGCTAATTGATC T|160|R T|160|M POL5 POLymerase 1022.0 0 0 0 0 0.4641931930090066 P39985 0.06378229707479477 0.5584065914154053 42.12276357609136 45.0 0.0 no 3042 chrV_51177 9294 essential YEL055C 343 - ACGCTCATCTTTGCCCTTCA E|120|D silent|GAG>GAA|E|120 R|121|P R|121|H POL5 POLymerase 1022.0 0 0 0 0 -0.13211422950755314 P39985 0.0 0.0 0.0 57.63727776781832 50.0 0.0 no 3043 chrV_51449r 9303 essential YEL055C 68 + TGCAGCTGTCGCATTAATAA A|24|G A|24|V A|25|G A|25|V POL5 POLymerase 1022.0 0 0 0 0 -0.4134460469150625 P39985 0.05395744740962982 0.017840106040239334 0.030499139800667763 0.2789490818977356 45.486733982361095 40.0 0.0 no 3044 chrV_58405r 9305 high_effect YEL051W 30 - AAACCCAGCGTCATACGCGT G|16|A G|16|D G|16|R G|16|S VMA8 Vacuolar Membrane Atpase 256.0 0 1 0 0 -1.2362902419321231 P32610 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.3015473783016205 0.1600266546010971 0.1200113371014595 0.5341490507125854 52.79892555861318 55.00000000000001 1.0 no 3045 chrV_58560 9307 high_effect YEL051W 182 + GCAAACTGCTGCCTTTTCCT Q|62|E Q|62|* T|63|S T|63|I VMA8 Vacuolar Membrane Atpase 256.0 0 0 0 0 -0.5995595223102911 P32610 0.9590039849281312 0.9491789937019348 0.9472420215606691 0.023559102788567543 0.5278949737548828 0.18523108959198 55.28499403346007 50.0 1.0 no 3046 chrV_58720r 9311 high_effect YEL051W 345 - AATCTGAAATCATTAATTTC R|121|T R|121|K VMA8 Vacuolar Membrane Atpase 256.0 0 0 0 0 0.5508655067781254 P32610 0.932735025882721 0.955805003643036 0.2755746841430664 0.5782217383384705 31.260477898872754 20.0 1.0 no 3047 chrV_58833 9314 high_effect YEL051W 455 + ACAGACTGCATTTATTATTT Q|153|E Q|153|* T|154|S T|154|I VMA8 Vacuolar Membrane Atpase 256.0 0 0 0 0 -0.1645046947853283 P32610 0.9590039849281312 0.9491789937019348 0.9472420215606691 0.0 0.1803138107061386 0.0050649200566113 39.56046545411243 25.0 1.0 no 3048 chrV_69992r 9324 high_effect YEL044W 238 - CTCTGCAGCTTTGTTAGCCT E|86|Q E|86|K A|85|P A|85|T IES6 Ino Eighty Subunit 166.0 0 0 0 0 -0.4540715253272128 P32617 0.361091822385788 0.3481660485267639 0.1372748613357544 0.4865249395370483 57.36058931288619 50.0 1.0 no 3049 chrV_76088r 9332 no_effect YEL041W 147 - TAACCGCACCTCATTAAGCC G|55|A G|55|D G|55|R G|55|S 0 0 0 0 0.11752349891511045 P32622 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.3455914556980133 0.12868985533714294 0.8977422118186951 0.2824167609214783 51.12816110314691 50.0 1.0 no 3050 chrV_76348r 9337 no_effect YEL041W 407 - GTACATATACAGTTATTGAA V|142|L V|142|I 0 0 0 0 -1.6039102020211782 P32622 0.9539830088615416 0.9574310183525084 0.044619712978601456 0.096229687333107 35.664747352323104 25.0 1.0 no 3051 chrV_76574 9340 no_effect YEL041W 630 + CCATTTGCCCTTGGATCATT P|211|R P|211|L 0 0 0 0 -0.2472658197126577 P32622 0.9432820081710817 0.9430609941482544 0.063402459025383 0.08217941224575043 54.150976130218105 45.0 1.0 no 3052 chrV_76767r 9344 no_effect YEL041W 826 - TTCGTTCAATACGTGATGTT E|282|Q E|282|K L|280|F silent|TTG>TTA|L|280 0 0 0 0 0.2633842972793876 P32622 0.956179976463318 0.9475290179252625 0.9587849974632264 0.011738903820514679 0.009069475345313549 0.005807102657854557 42.911328267814326 35.0 1.0 no 3053 chrV_76843 9346 no_effect YEL041W 899 + AAACGACTCACTAATGACTA N|301|K silent|AAC>AAT|N|301 D|302|E silent|GAC>GAT|D|302 0 0 0 0 1.3696936401716566 P32622 0.9439849853515624 0.9532920122146606 0.006554958876222372 0.3256756961345673 37.43311065164846 35.0 1.0 no 3054 chrV_76905r 9349 no_effect YEL041W 964 - TGCACTCAATGAGTATGCCG A|328|P A|328|T S|327|T S|327|N 0 0 0 0 -0.020952985629753854 P32622 0.9573720097541808 0.9523990154266356 0.9512869715690612 0.9536849856376648 0.0 0.0 0.006162240169942379 0.002028236398473382 48.98975244855978 50.0 1.0 no 3055 chrV_76946r 9350 no_effect YEL041W 1005 - ACCGCTATGGCATTTACGCT silent|GCG>GCC|A|341 silent|GCG>GCA|A|341 V|342|L V|342|M 0 0 0 0 -0.5944099676980457 P32622 0.9539830088615416 0.9587630033493042 0.8109784722328186 0.011512774974107742 53.505292442856216 50.0 1.0 no 3056 chrV_76959r 9354 no_effect YEL041W 1018 - ACATATAGGCGTCACCGCTA C|346|S C|346|Y 0 0 0 0 0.3987258712431573 P32622 0.9421560168266296 0.9290120005607604 0.0 0.0 52.14380679970395 50.0 1.0 no 3057 chrV_77015r 9356 no_effect YEL041W 1074 - ACTTTTAATTCCATGCTATC V|365|L V|365|I 0 0 0 0 0.21814418311090888 P32622 0.9539830088615416 0.9574310183525084 0.06399203091859818 0.7656591534614563 42.4583775918278 30.0 1.0 no 3058 chrV_83454r 9359 high_effect YEL036C 1076 + CAGCGACGACTTAAAGCACA S|360|R silent|AGC>AGT|S|360 D|361|E silent|GAC>GAT|D|361 ANP1 ANP and osmotic sensitive 500.0 0 0 0 0 0.7402315765814176 P32629 0.9417110085487366 0.9532920122146606 0.4099710881710053 0.10890725255012512 45.22193344628505 50.0 0.0 no 3059 chrV_83521 9363 high_effect YEL036C 1012 - GACATTGTAATTCATCCTGC V|344|L V|344|I ANP1 ANP and osmotic sensitive 500.0 0 0 0 0 -0.2805234929180752 P32629 0.9539830088615416 0.9574310183525084 0.008635310456156729 0.0355241633951664 45.75409223633898 40.0 0.0 no 3060 chrV_83669 9367 high_effect YEL036C 864 - TCGTCTTCTGGATTACCGTT E|295|Q E|295|K D|294|H D|294|N ANP1 ANP and osmotic sensitive 500.0 0 0 0 0 -0.23522315765441 P32629 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.07608387619256972 0.18873654305934906 0.06740899384021759 0.1836876720190048 51.48124776940893 45.0 0.0 no 3061 chrV_83745r 9370 high_effect YEL036C 785 + AGACGAAGATGCTGTCATTG D|263|E silent|GAC>GAT|D|263 ANP1 ANP and osmotic sensitive 500.0 0 0 0 0 1.674371036171472 P32629 0.9532920122146606 0.03346284106373787 43.67499332558822 45.0 0.0 no 3062 chrV_83803 9376 high_effect YEL036C 730 - CTTCCATGAATTTAAATCGT W|249|C W|249|* W|249|S W|249|* ANP1 ANP and osmotic sensitive 500.0 0 0 0 0 -1.7679874725711953 P32629 0.8858469724655151 0.8858469724655151 0.0 0.0 39.21098614624219 30.0 0.0 no 3063 chrV_83834 9377 high_effect YEL036C 699 - TTTCCCAGCCAGTCTGGTAA G|239|A G|239|E G|239|R G|239|R ANP1 ANP and osmotic sensitive 500.0 0 0 0 0 0.36048115268119824 P32629 0.9499930143356324 0.9438679814338684 0.941340982913971 0.941340982913971 0.012472930364310741 0.016310887411236763 0.007669419515877962 0.007669419515877962 57.10001788270319 50.0 0.0 no 3064 chrV_83893 9380 high_effect YEL036C 640 - ATGCATTAGATCCTCCATGA M|219|I M|219|I ANP1 ANP and osmotic sensitive 500.0 0 0 0 0 0.18407429100454376 P32629 0.9553959965705872 0.9553959965705872 0.16344472765922546 0.16344472765922546 49.14806148440477 40.0 0.0 no 3065 chrV_83938 9383 high_effect YEL036C 595 - CACGTCTCTCCAGTAAACCC V|205|L V|205|M D|204|H D|204|N ANP1 ANP and osmotic sensitive 500.0 0 0 0 0 -0.2771374082585459 P32629 0.9539830088615416 0.9587630033493042 0.9486550092697144 0.956179976463318 0.08021943271160126 0.025488274171948436 0.0 0.0 53.22034801792324 55.00000000000001 0.0 no 3066 chrV_83955r 9385 high_effect YEL036C 575 + CCTGAAACCATACCACTCCT L|193|V silent|CTG>TTG|L|193 ANP1 ANP and osmotic sensitive 500.0 0 0 0 0 -0.04653007351228283 P32629 0.9512209892272948 0.007152104284614325 51.83398770328677 50.0 0.0 no 3067 chrV_83956r 9387 high_effect YEL036C 574 + CCCTGAAACCATACCACTCC L|193|V silent|CTG>TTG|L|193 silent|GCC>GCG|A|192 silent|GCC>GCT|A|192 ANP1 ANP and osmotic sensitive 500.0 0 0 0 0 -0.12831764501702092 P32629 0.9512209892272948 0.007152104284614325 53.53149703300796 55.00000000000001 0.0 no 3068 chrV_84043r 9399 high_effect YEL036C 487 + AGTCCTTTTCTGATCGTCAC S|164|C S|164|F silent|TCC>TCG|S|164 silent|TCC>TCT|S|164 ANP1 ANP and osmotic sensitive 500.0 0 0 0 0 0.628053365532802 P32629 0.945252001285553 0.9294660091400146 0.007137146778404713 0.006074124947190285 51.1768338094579 45.0 0.0 no 3069 chrV_84087r 9400 high_effect YEL036C 443 + TAACATCGAAATCTATGAGA N|149|K silent|AAC>AAT|N|149 I|150|M silent|ATC>ATT|I|150 ANP1 ANP and osmotic sensitive 500.0 0 0 0 0 0.0552883332924613 P32629 0.9439849853515624 0.9598389863967896 0.2488452643156052 0.005182197783142328 34.80523789911763 30.0 0.0 no 3070 chrV_84115r 9401 high_effect YEL036C 415 + CGCAACAAGACAAGTCCAAA Q|140|E Q|140|* Q|141|E Q|141|* ANP1 ANP and osmotic sensitive 500.0 0 0 0 0 -0.457952776966021 P32629 0.9590039849281312 0.9590039849281312 0.2963109314441681 1.0 41.74474410403587 45.0 0.0 no 3071 chrV_84206 9403 high_effect YEL036C 327 - GACAGATCAATCAGGTTGTG silent|CTG>CTC|L|115 silent|CTG>CTA|L|115 ANP1 ANP and osmotic sensitive 500.0 0 0 0 0 0.11738176409570485 P32629 44.271351093294236 45.0 0.0 no 3072 chrV_84241 9405 high_effect YEL036C 292 - ATTCAGATGGTTAAAAAACA silent|CTG>CTC|L|103 silent|CTG>CTA|L|103 ANP1 ANP and osmotic sensitive 500.0 0 0 0 0 -3.6883301117852136 P32629 32.85933746188476 25.0 0.0 yes 3073 chrV_84314r 9408 high_effect YEL036C 216 + AACAAAGATGGTTGGCAACA N|73|K silent|AAC>AAT|N|73 ANP1 ANP and osmotic sensitive 500.0 0 0 0 0 0.11208407608791583 P32629 0.9439849853515624 0.011803217232227324 40.775526078296366 40.0 0.0 no 3074 chrV_84321 9409 high_effect YEL036C 212 - GCCAACCATCTTTGTTGCCT W|77|S W|77|* W|77|C W|77|* ANP1 ANP and osmotic sensitive 500.0 0 0 0 0 0.6169692302744815 P32629 0.8858469724655151 0.8858469724655151 0.3978960812091827 0.17942821979522705 57.23335245014306 50.0 0.0 no 3075 chrV_85310r 9425 essential YEL035C 213 + AACGCTACGGAATACATCGA N|72|K silent|AAC>AAT|N|72 A|73|G A|73|V 0 0 0 0 -0.24152138178350024 P32630 0.9439849853515624 0.9484469890594482 0.9504740238189696 42.93354680542785 45.0 0.0 no 3076 chrV_85311r 9426 essential YEL035C 212 + TAACGCTACGGAATACATCG N|72|K silent|AAC>AAT|N|72 A|73|G A|73|V 0 0 0 0 0.3648253271640961 P32630 0.9439849853515624 0.9484469890594482 0.9504740238189696 41.406293115078476 45.0 0.0 no 3077 chrV_85461 9432 essential YEL035C 65 - CGTCGTCGTCGATCGGCTTT D|28|H D|28|N D|27|H D|27|N 0 0 0 0 0.3660536017848238 P32630 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 55.75082170169367 60.0 0.0 no 3078 chrV_87097r 9445 essential YEL032W 163 - ATCTTGATCATCGTTGTAGT D|61|H D|61|N MCM3 MiniChromosome Maintenance 971.0 0 0 0 0 0.4711552101113482 P24279 1.011430025100708 0.9817010164260864 45.385811352448165 35.0 1.0 no 3079 chrV_87323 9453 essential YEL032W 386 + TACTGACCTAGCAGATTCCA T|130|S T|130|I D|131|E silent|GAC>GAT|D|131 MCM3 MiniChromosome Maintenance 971.0 0 0 0 0 -0.0583791365974064 P24279 1.1038800477981567 1.0804400444030762 1.0199099779129028 0.3690938353538513 0.10429129749536514 1.0 50.42875080687969 45.0 1.0 no 3080 chrV_87390 9458 essential YEL032W 453 + CCTTGGAAGCTTTCGTTCAA P|152|R P|152|L MCM3 MiniChromosome Maintenance 971.0 0 0 0 0 0.5954497687964222 P24279 0.9826639890670776 1.0016000270843506 0.5557689070701599 0.3987396061420441 48.92307204615099 45.0 1.0 no 3081 chrV_87452 9459 essential YEL032W 515 + GGCACAACATTTAAACAAAC A|173|G A|173|V Q|174|E Q|174|* MCM3 MiniChromosome Maintenance 971.0 0 0 0 0 -0.5142807567269936 P24279 0.974888026714325 0.8960899710655212 1.0272300243377686 0.07815245538949966 0.025244344025850296 1.0 35.79907401946957 35.0 1.0 no 3082 chrV_87524 9462 essential YEL032W 587 + TATCAGATCTGTCCACTACG I|197|M silent|ATC>ATT|I|197 MCM3 MiniChromosome Maintenance 971.0 0 0 0 0 -0.18585084202116148 P24279 1.0062199831008911 0.04991276189684868 47.117566112405434 45.0 1.0 no 3083 chrV_87614 9465 essential YEL032W 677 + AACGCCTGCCATCTATCCAA T|227|R T|227|M P|228|A P|228|S MCM3 MiniChromosome Maintenance 971.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.20374008893713014 P24279 0.9508609771728516 0.945649027824402 1.0191700458526611 1.0233399868011477 0.05175555869936943 0.06541318446397781 0.384480744600296 1.0 53.45802408927807 50.0 1.0 no 3084 chrV_87630r 9468 essential YEL032W 696 - TTACCTTCAGTGTCCTCCGT G|238|A G|238|D G|238|R G|238|S MCM3 MiniChromosome Maintenance 971.0 0 0 0 0 -0.4525660996996566 P24279 0.9437639713287354 0.9224119782447816 0.9196460247039796 0.9456070065498352 0.032783329486846924 0.021076584234833717 0.014531766064465048 0.02441236563026905 58.4150769151554 50.0 1.0 no 3085 chrV_87651 9469 essential YEL032W 714 + AACAAACTAACCACCGAATA N|239|K silent|AAC>AAT|N|239 L|241|V silent|CTA>TTA|L|241 MCM3 MiniChromosome Maintenance 971.0 0 0 0 0 1.3614177689716012 P24279 0.952219009399414 0.9477670192718506 0.0 0.0 38.18683147541293 35.0 1.0 no 3086 chrV_87652 9470 essential YEL032W 715 + ACAAACTAACCACCGAATAT N|239|K silent|AAC>AAT|N|239 L|241|V silent|CTA>TTA|L|241 MCM3 MiniChromosome Maintenance 971.0 0 0 0 0 1.1624190587147396 P24279 0.952219009399414 0.9477670192718506 0.0 0.0 39.337180760936796 35.0 1.0 no 3087 chrV_87861 9481 essential YEL032W 924 + TCCAACTCTAATACATTGAT silent|TCC>TCG|S|309 silent|TCC>TCT|S|309 S|309|C S|309|F MCM3 MiniChromosome Maintenance 971.0 0 0 0 0 -0.029034575278031938 P24279 0.9326710104942322 0.9524869918823242 0.054519586265087135 0.05286658555269241 39.6900607997942 30.0 1.0 no 3088 chrV_87862 9483 essential YEL032W 925 + CCAACTCTAATACATTGATC silent|TCC>TCG|S|309 silent|TCC>TCT|S|309 N|310|K silent|AAC>AAT|N|310 MCM3 MiniChromosome Maintenance 971.0 0 0 0 0 -0.14480320012303866 P24279 0.9993529915809632 0.10389262437820436 39.6900607997942 35.0 1.0 no 3089 chrV_87917 9484 essential YEL032W 980 + TCCTCTCCACGCCAGATCCA P|328|R P|328|L P|328|A P|328|S MCM3 MiniChromosome Maintenance 971.0 0 0 0 0 0.02992301861585917 P24279 0.9773079752922058 0.9986029863357544 1.0113400220870972 1.0032600164413452 0.8118976354598999 0.5816932916641235 0.5099107027053833 0.4290675222873688 62.07753874903318 60.0 1.0 no 3090 chrV_88032 9488 essential YEL032W 1095 + TCTTTAGCGCCTTCTATTTA S|366|C S|366|F MCM3 MiniChromosome Maintenance 971.0 0 0 0 0 0.1939709479966958 P24279 0.8553090095520021 0.8282279968261719 0.0 0.0 48.853433220781774 35.0 1.0 no 3091 chrV_88174 9493 essential YEL032W 1237 + CTGCCAAGTCCCAATTGCTA A|414|G A|414|V silent|GCC>GCG|A|414 silent|GCC>GCT|A|414 MCM3 MiniChromosome Maintenance 971.0 0 0 0 0 0.2845864669299491 P24279 0.9510049819946288 0.8557800054550171 0.02338459156453609 0.007416409905999898 54.065411948469155 50.0 1.0 no 3092 chrV_88184r 9495 essential YEL032W 1250 - TCAACACAAACCTTAGCAAT L|423|F silent|TTG>TTA|L|423 silent|GTG>GTC|V|422 silent|GTG>GTA|V|422 MCM3 MiniChromosome Maintenance 971.0 0 0 0 0 -0.05006224218764771 P24279 0.8657379746437073 0.011844483204185964 40.22955623962514 35.0 1.0 no 3093 chrV_88183r 9496 essential YEL032W 1249 - CAACACAAACCTTAGCAATT silent|GTG>GTC|V|422 silent|GTG>GTA|V|422 V|422|L V|422|M MCM3 MiniChromosome Maintenance 971.0 0 0 0 0 0.3305594015410156 P24279 0.9294670224189758 0.8861079812049866 0.017912358045578003 0.00529340049251914 39.64447343352021 35.0 1.0 no 3094 chrV_88215 9497 essential YEL032W 1278 + TCACTGGCAATTGCTACTAC L|428|V silent|CTG>TTG|L|428 S|427|* S|427|L MCM3 MiniChromosome Maintenance 971.0 0 0 0 0 1.0663517698863134 P24279 0.9420400261878968 1.0456600189208984 0.020890885964035988 0.00460062688216567 46.973823604347565 45.0 1.0 no 3095 chrV_88221 9498 essential YEL032W 1284 + GCAATTGCTACTACTGGTAG A|429|G A|429|V MCM3 MiniChromosome Maintenance 971.0 0 0 0 0 1.0986922965685293 P24279 0.9455639719963074 0.9382860064506532 0.0 0.0 46.283050108641426 45.0 1.0 no 3096 chrV_88264r 9502 essential YEL032W 1330 - CCTATCAGTAGTGACCGCTG R|450|T R|450|K D|449|H D|449|N MCM3 MiniChromosome Maintenance 971.0 0 1 0 0 0.10802878841061564 P24279 1.0009599924087524 1.0365400314331057 0.8759239912033081 0.9363020062446594 0.12597791850566864 1.0 0.0 0.0 53.43376107377628 55.00000000000001 1.0 no 3097 chrV_88385 9509 essential YEL032W 1448 + AGTCGCCATTCATGAAGTAA silent|GTC>GTG|V|484 silent|GTC>GTT|V|484 A|485|G A|485|V MCM3 MiniChromosome Maintenance 971.0 0 0 0 0 -0.18556309074559887 P24279 0.8644959926605225 0.8887519836425781 0.0 0.0 45.55383522284728 40.0 1.0 no 3098 chrV_88477 9511 essential YEL032W 1540 + CTGCCGCAAATCCCGTTTTT A|515|G A|515|V silent|GCC>GCG|A|515 silent|GCC>GCT|A|515 MCM3 MiniChromosome Maintenance 971.0 0 0 0 0 -0.5621657395445048 P24279 0.8569729924201965 0.8559970259666443 0.0 0.0 53.95829302641016 50.0 1.0 no 3099 chrV_88615r 9519 essential YEL032W 1681 - TCTTAAGACATGCTCACTAA R|567|T R|567|K MCM3 MiniChromosome Maintenance 971.0 0 0 0 0 -0.2845615432965699 P24279 0.931859016418457 0.9897400140762328 0.015788594260811806 0.16194432973861694 41.2001533439369 35.0 1.0 no 3100 chrV_88653r 9520 essential YEL032W 1719 - TCACCCTCTAAATAACCTGG G|579|A G|579|D E|580|Q E|580|K MCM3 MiniChromosome Maintenance 971.0 0 0 0 0 -6.1058714508972685 P24279 0.9239559769630432 0.9056479930877686 0.96526300907135 0.9275749921798706 0.0389271080493927 0.010969722643494606 0.1386340856552124 0.18713748455047607 46.89779392402454 45.0 1.0 yes 3101 chrV_88650 9521 essential YEL032W 1713 + TTGCCTCCAGGTTATTTAGA P|573|A P|573|S P|573|R P|573|L MCM3 MiniChromosome Maintenance 971.0 0 0 0 0 -0.4592377183716949 P24279 1.0558400154113772 1.0427000522613523 1.0157400369644165 0.9833109974861144 0.6284101605415344 0.6045790910720825 0.5236291885375977 0.25090140104293823 51.115971838707885 40.0 1.0 no 3102 chrV_88734 9523 essential YEL032W 1797 + CCTGAAGAGCATTCCAACTC P|600|R P|600|L MCM3 MiniChromosome Maintenance 971.0 0 0 0 0 0.948758665186272 P24279 0.9538050293922424 0.9669110178947448 0.4868130385875702 0.2450772821903229 48.86163171708603 50.0 1.0 no 3103 chrV_88814r 9528 essential YEL032W 1880 - TAGCACCTGCTTGTAATAAG A|633|P A|633|T G|632|A G|632|D MCM3 MiniChromosome Maintenance 971.0 0 0 0 0 -1.170992225419582 P24279 0.9732310175895692 0.9646989703178406 1.0809700489044192 1.0570600032806396 0.21322795748710632 0.4539015889167786 0.024773605167865757 0.2130054384469986 43.97227850069783 40.0 1.0 no 3104 chrV_88809 9529 essential YEL032W 1872 + TTCAACCCCTTATTACAAGC F|625|L silent|TTC>TTT|F|625 N|626|K silent|AAC>AAT|N|626 MCM3 MiniChromosome Maintenance 971.0 0 0 0 0 0.3043246612307138 P24279 1.0788999795913696 0.9427360296249391 0.0666646733880043 0.04578859359025955 47.26258076766418 40.0 1.0 no 3105 chrV_89062 9534 essential YEL032W 2125 + CCACAGCTCACGCCAAAGTC T|710|R T|710|I silent|GCC>GCG|A|709 silent|GCC>GCT|A|709 MCM3 MiniChromosome Maintenance 971.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.6377046945468571 P24279 0.8546779751777649 0.8666750192642212 0.00669368589296937 0.007981119677424429 54.417338577098405 60.0 1.0 no 3106 chrV_88912 9536 essential YEL032W 1975 + ACGTTCAATATGCCAAGGAA Y|659|* silent|TAC>TAT|Y|659 Q|661|E Q|661|* MCM3 MiniChromosome Maintenance 971.0 0 0 0 0 -1.4621919462930022 P24279 0.919165015220642 0.023103123530745503 43.43296898744035 40.0 1.0 no 3107 chrV_97336 9544 high_effect YEL029C 441 - ATCTCCAGCTCAAATTGATT E|153|D silent|GAG>GAA|E|153 E|153|Q E|153|K BUD16 BUD site selection 312.0 0 0 0 0 0.3650448282638815 P39988 0.94931298494339 0.956179976463318 0.9475290179252625 0.0 0.0 0.0 44.66442779615545 35.0 0.0 no 3108 chrV_97441r 9546 high_effect YEL029C 333 + GATCCTGTTATGGGTGACGA P|113|A P|113|S P|113|R P|113|L BUD16 BUD site selection 312.0 0 0 0 0 1.0042354167403944 P39988 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.0 0.0 0.0 0.0 50.69394268045824 50.0 0.0 no 3109 chrV_97450r 9547 high_effect YEL029C 324 + TGGCTTATGGATCCTGTTAT L|110|V L|110|F BUD16 BUD site selection 312.0 0 0 0 0 -0.734778233925013 P39988 0.9512209892272948 0.9587849974632264 0.4760089218616486 0.03172258287668228 49.41448256396706 40.0 0.0 no 3110 chrV_97463r 9548 high_effect YEL029C 311 + TCCAGAAATGATATGGCTTA P|105|R P|105|L P|105|A P|105|S BUD16 BUD site selection 312.0 0 0 0 0 -0.00698663904875685 P39988 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0787682756781578 0.022292645648121837 0.05615566298365593 0.03992066904902458 41.91053635058461 35.0 0.0 no 3111 chrV_97462 9549 high_effect YEL029C 315 - TCCATAAGCCATATCATTTC M|111|I M|111|I D|112|H D|112|N BUD16 BUD site selection 312.0 0 0 0 0 -1.7083158879249771 P39988 0.9553959965705872 0.9553959965705872 0.9486550092697144 0.956179976463318 0.08888836950063705 0.08888836950063705 0.0 0.0 45.394678163869116 35.0 0.0 no 3112 chrV_97521 9554 high_effect YEL029C 256 - ACATCGAACGGAATTCTTAT C|92|S C|92|Y R|91|P R|91|Q BUD16 BUD site selection 312.0 0 0 0 0 -1.9462060882942005 P39988 0.9421560168266296 0.9290120005607604 0.9099509716033936 0.949662983417511 0.2283161580562592 0.172247976064682 0.1811070293188095 0.3889829218387604 0.8086000084877014 -0.4426000118255615 39.86279910142554 35.0 0.0 no 3113 chrV_97644 9557 high_effect YEL029C 133 - CACTTTATCTAAACCATATC V|51|L V|51|M BUD16 BUD site selection 312.0 0 0 0 0 0.093396908952169 P39988 0.9539830088615416 0.9587630033493042 0.4784280955791474 0.135776549577713 -0.5396000146865845 -0.8650000095367432 38.203938795308375 30.0 0.0 no 3114 chrV_97663r 9559 high_effect YEL029C 111 + GTTCAGTTTTCCAACCATAC Q|39|E Q|39|* BUD16 BUD site selection 312.0 0 0 0 0 -0.8155992525827297 P39988 0.9590039849281312 0.1652582287788391 47.87199750642343 40.0 0.0 no 3115 chrV_97748r 9563 high_effect YEL029C 26 + TCATGTTGTACATGGATATG H|10|D H|10|Y BUD16 BUD site selection 312.0 0 0 0 0 -0.2709638964232255 P39988 0.9473130106925964 0.9489949941635132 0.0 0.0 40.93524971382175 35.0 0.0 no 3116 chrV_100784 9566 high_effect YEL027W 15 + CCTGTCTACGCCCCTTTCTT P|6|R P|6|L silent|GTC>GTG|V|7 silent|GTC>GTT|V|7 VMA3 Vacuolar Membrane Atpase 160.0 0 0 0 0 -0.5295786839174452 P25515 0.014782103709876537 0.0013919612392783165 61.45577496852917 55.00000000000001 1.0 no 3117 chrV_100826 9570 high_effect YEL027W 57 + GCAATTATCTTCACCTCATT A|20|G A|20|V VMA3 Vacuolar Membrane Atpase 160.0 0 0 0 0 -1.1903077392893553 P25515 0.0871780589222908 0.004113272298127414 46.416145537315394 35.0 1.0 no 3118 chrV_100912r 9574 high_effect YEL027W 146 - GAACAATGTTCTTGAATAAT V|55|L V|55|I VMA3 Vacuolar Membrane Atpase 160.0 0 0 0 0 0.10167662500426797 P25515 0.10698754340410233 1.0 -0.44562000036239613 0.1685599982738495 33.33464762647032 25.0 1.0 no 3119 chrV_100924 9575 high_effect YEL027W 155 + GAACATTGTTCCTGTTATTA N|53|K silent|AAC>AAT|N|53 VMA3 Vacuolar Membrane Atpase 160.0 0 0 0 0 0.3074286463969702 P25515 0.036651361733675 42.2347494378614 30.0 1.0 no 3120 chrV_101046r 9579 high_effect YEL027W 280 - ACTCAAACCGACTGATAGAC L|99|F silent|TTG>TTA|L|99 S|100|T S|100|N VMA3 Vacuolar Membrane Atpase 160.0 0 0 0 0 0.16945912530241508 P25515 0.06116385757923126 0.3932873904705048 0.03636786714196205 -0.362419992685318 42.292110246489976 45.0 1.0 no 3121 chrV_101129 9582 high_effect YEL027W 360 + CAACAACCAAGATTATTCGT Q|122|E Q|122|* P|123|A P|123|S VMA3 Vacuolar Membrane Atpase 160.0 0 0 0 0 0.8810973929826961 P25515 0.08275508880615234 0.008560863323509693 0.20650459825992584 39.79318770259249 35.0 1.0 no 3122 chrV_102060 9588 essential YEL026W 117 + GCTACCAAAACTTTGAACCG A|40|G A|40|V T|41|S T|41|I SNU13 Small NUclear ribonucleoprotein associated 126.0 0 1 0 0 -1.0733186226531162 P39990 0.9484469890594482 0.9504740238189696 0.9491789937019348 0.9472420215606691 0.05041786655783653 0.2580538094043732 0.008619075641036034 0.2320594936609268 2.0011000633239746 1.2527199983596802 0.9393600225448608 -1.596119999885559 1.1494799852371216 1.6827199459075928 43.367472891605416 45.0 1.0 no 3123 chrV_102144r 9589 essential YEL026W 204 - TTCTTGTCTTCACATAGTAA K|74|N silent|AAG>AAA|K|74 SNU13 Small NUclear ribonucleoprotein associated 126.0 0 0 0 0 0.3639217652047679 P39990 0.9355990290641784 0.10999657213687897 1.0772199630737305 41.941610896500386 30.0 1.0 no 3124 chrV_120700 9593 essential YEL019C 582 - TTACATTTTCTTGATATCAA C|200|S C|200|Y MMS21 Methyl MethaneSulfonate sensitivity 267.0 0 0 0 0 0.10523745782108744 P38632 0.0 0.0 4.254079818725587 10.613180160522461 0.9830200076103209 1.3396199941635132 35.85488773419564 20.0 0.0 no 3125 chrV_120975r 9598 essential YEL019C 304 + CGCAAATCGACCTTTCTACC Q|103|E Q|103|* MMS21 Methyl MethaneSulfonate sensitivity 267.0 0 0 0 0 0.7402861326288508 P38632 0.986342430114746 -0.5167800188064575 48.50845327149227 50.0 0.0 no 3126 chrV_121067r 9600 essential YEL019C 212 + ACTCCTCTCGACATACGAAT silent|CTC>CTG|L|72 silent|CTC>CTT|L|72 L|72|V L|72|F MMS21 Methyl MethaneSulfonate sensitivity 267.0 0 0 0 0 -1.5422532748151856 P38632 0.2976842820644379 0.06716332584619522 0.6352800130844116 0.15197999775409698 0.6581799983978271 0.2786400020122528 1.4275200366973877 0.5695000290870667 46.773796306508245 45.0 0.0 no 3127 chrV_121120 9601 essential YEL019C 162 - TCTTCAATGCCGATGGTGGA E|61|Q E|61|K E|60|Q E|60|K MMS21 Methyl MethaneSulfonate sensitivity 267.0 0 0 0 0 0.5752402638618833 P38632 0.23151175677776334 0.6212390065193176 0.2287525087594986 0.3087212145328522 -0.4238600134849548 -0.3957599997520447 -0.6002799868583679 -0.6113799810409546 51.289866669535066 50.0 0.0 no 3128 chrV_121129r 9602 essential YEL019C 150 + TCTACATCTCCTTCCACCAT S|51|C S|51|F T|52|R T|52|I MMS21 Methyl MethaneSulfonate sensitivity 267.0 0 0 0 0 0.5084869851322502 P38632 0.20150579512119293 0.6382174491882324 0.1332520991563797 0.07368926703929901 -0.06614000350236893 -0.21991999447345734 0.8235200047492981 1.2695000171661377 -0.20295999944210047 -0.6958799958229065 0.6724600195884705 0.1004600003361702 54.80715343595296 45.0 0.0 no 3129 chrV_120796 9606 essential YEL019C 486 - TCTGCGGGGTTTTGCAGATC D|169|H D|169|N A|168|P A|168|T MMS21 Methyl MethaneSulfonate sensitivity 267.0 0 0 0 0 -0.609011735776822 P38632 0.07162237167358397 0.28703421354293823 0.2577659487724304 0.4396604597568512 0.8210800290107727 -0.125560000538826 4.5503201484680185 2.142780065536499 8.004879951477049 2.399300098419189 55.051986582692614 55.00000000000001 0.0 no 3130 chrV_125167 9607 no_effect YEL016C 1032 - TTCAAACATACCATCATCAT L|350|F silent|TTG>TTA|L|350 C|349|S C|349|Y 0 0 0 0 0.8759884619280356 P39997 0.1894710808992386 0.8720255494117737 0.9094860553741456 40.32216161469472 30.0 0.0 no 3131 chrV_125166 9609 no_effect YEL016C 1033 - TTTCAAACATACCATCATCA L|350|F silent|TTG>TTA|L|350 0 0 0 0 -0.25610491965460125 P39997 0.1894710808992386 40.561631914168686 30.0 0.0 no 3132 chrV_125585 9621 no_effect YEL016C 614 - TTTCCCTAGGTACATCCCCG E|211|Q E|211|K R|210|S silent|AGG>AGA|R|210 0 0 0 0 0.19921468149597027 P39997 0.21727880835533145 0.31291037797927856 0.6427299976348877 58.81585577804884 55.00000000000001 0.0 no 3133 chrV_125611 9623 no_effect YEL016C 588 - TCATACACAACCTCACTTCC E|203|Q E|203|K silent|GTG>GTC|V|201 silent|GTG>GTA|V|201 0 0 0 0 -0.3170072057031201 P39997 0.206517830491066 0.2877463400363922 48.65509621380312 45.0 0.0 no 3134 chrV_125662r 9627 no_effect YEL016C 534 + CTACTGCAAACTGAATCGCA L|180|V silent|CTG>TTG|L|180 Q|181|E Q|181|* 0 0 0 0 0.7706379964248005 P39997 1.0 0.19132623076438904 43.863664459213 45.0 0.0 no 3135 chrV_125875 9633 no_effect YEL016C 324 - GTCGTGATATTCATATCGTA silent|ACG>ACC|T|114 silent|ACG>ACA|T|114 0 0 0 0 0.5493967109560761 P39997 43.2823544187533 35.0 0.0 no 3136 chrV_125939 9634 no_effect YEL016C 260 - TTGCATCTATCAATCTCGGA A|93|P A|93|T D|92|H D|92|N 0 0 0 0 -0.4969152898599815 P39997 0.2277880311012268 0.4700988531112671 0.03494303300976753 0.3495724201202393 46.083891243719556 40.0 0.0 no 3137 chrV_126028 9635 no_effect YEL016C 171 - GATCTATTCGCAATTGTCCG R|63|T R|63|K 0 1 0 0 -0.4226703086656062 P39997 0.4853029847145081 0.4764910638332367 47.29747588211024 45.0 0.0 no 3138 chrV_149146 9640 essential YEL002C 849 - ACTTTGTCCTTGATTTTGTA V|290|L V|290|I WBP1 Wheat germ agglutinin-Binding Protein 430.0 0 0 0 0 1.2927775210436676 P33767 0.9539830088615416 0.9574310183525084 0.08960484713315964 1.0 45.43650809366494 30.0 0.0 no 3139 chrV_149404r 9648 essential YEL002C 588 + ACATCCTTTACTGAGTCCAA T|197|R T|197|I S|198|C S|198|F WBP1 Wheat germ agglutinin-Binding Protein 430.0 0 0 0 0 -0.17104692227463564 P33767 0.9476869702339172 0.9472420215606691 0.945252001285553 0.9294660091400146 0.1673404723405838 0.03902460634708405 0.0 0.0 48.28265637519411 40.0 0.0 no 3140 chrV_149410 9650 essential YEL002C 585 - GACTCAGTAAAGGATGTTCT E|201|D silent|GAG>GAA|E|201 E|201|Q E|201|K WBP1 Wheat germ agglutinin-Binding Protein 430.0 0 1 0 0 0.6166321272301004 P33767 0.94931298494339 0.956179976463318 0.9475290179252625 0.34893062710762024 0.43693608045578 0.5398580431938171 43.16719267124876 40.0 0.0 no 3141 chrV_149557 9652 essential YEL002C 438 - ACCACTAGCTCTTCTGAGGA silent|GTG>GTC|V|152 silent|GTG>GTA|V|152 V|153|L V|153|I WBP1 Wheat germ agglutinin-Binding Protein 430.0 0 0 0 1 -1.1815478182574384 P33767 0.9539830088615416 0.9574310183525084 0.4632326662540436 0.9160788655281068 53.267413493776075 50.0 0.0 no 3142 chrV_149496 9653 essential YEL002C 499 - AACAAAATCCTCGCTTTTTC V|173|L V|173|I WBP1 Wheat germ agglutinin-Binding Protein 430.0 0 1 0 0 0.7701834542572282 P33767 0.9539830088615416 0.9574310183525084 0.4131479263305664 0.2936407625675201 41.51110503357614 35.0 0.0 no 3143 chrV_149742 9656 essential YEL002C 253 - CGCTAAATTCTTGCCTCCTT A|91|P A|91|T WBP1 Wheat germ agglutinin-Binding Protein 430.0 0 1 0 0 -0.3801156350226603 P33767 0.9573720097541808 0.9523990154266356 0.2087496966123581 0.7450723648071289 51.45743361710237 45.0 0.0 no 3144 chrV_149972r 9660 essential YEL002C 20 + TTTCTTTTGTATCCTTCTGC F|8|L silent|TTC>TTT|F|8 WBP1 Wheat germ agglutinin-Binding Protein 430.0 0 0 0 0 0.0005293424441404904 P33767 0.9387490153312684 0.8248708844184875 49.04503553933216 35.0 0.0 no 3145 chrV_149957r 9661 essential YEL002C 35 + TCTGCAGGCCATTTTCGTTG L|13|V silent|CTG>TTG|L|13 Q|14|E Q|14|* WBP1 Wheat germ agglutinin-Binding Protein 430.0 0 0 0 0 -2.1119627582891924 P33767 0.9512209892272948 0.9590039849281312 0.30182889103889465 0.54652339220047 54.18507694736304 50.0 0.0 yes 3146 chrV_149956r 9662 essential YEL002C 36 + CTGCAGGCCATTTTCGTTGT Q|14|E Q|14|* WBP1 Wheat germ agglutinin-Binding Protein 430.0 0 0 0 0 0.6775272224248381 P33767 0.9590039849281312 0.54652339220047 55.7732073187421 50.0 0.0 no 3147 chrV_158101r 9667 essential YER003C 902 + AGGCTTCACTCCAAAATTCA silent|GGC>GGG|G|302 silent|GGC>GGT|G|302 F|303|L silent|TTC>TTT|F|303 PMI40 PhosphoMannose Isomerase 429.0 0 0 0 1 1.132396536265576 P29952 0.9677240252494812 1.0 46.061048301665146 40.0 0.0 no 3148 chrV_158121r 9668 essential YER003C 882 + TCTGACAACGTAGTTAGAGC S|295|C S|295|F D|296|E silent|GAC>GAT|D|296 PMI40 PhosphoMannose Isomerase 429.0 0 0 0 0 -0.8440819861849407 P29952 0.9879119992256165 0.9685909748077391 0.9783369898796082 0.0 0.0 0.0 44.39405625147101 45.0 0.0 no 3149 chrV_158217r 9671 essential YER003C 786 + AATCACTGCAGATTGAATGC H|264|D H|264|Y H|264|Q silent|CAC>CAT|H|264 PMI40 PhosphoMannose Isomerase 429.0 0 0 0 0 -1.1410084683020487 P29952 0.9669790267944336 0.9671300053596495 0.9784529805183412 0.12894482910633087 1.0 0.1844460517168045 42.13135321171575 40.0 0.0 no 3150 chrV_158342 9674 essential YER003C 664 - ATTCTTTGATCTTTCGACCA K|227|N silent|AAG>AAA|K|227 PMI40 PhosphoMannose Isomerase 429.0 0 1 0 0 0.4459921427039548 P29952 0.9443619847297668 0.18057098984718326 46.36551015224808 35.0 0.0 no 3151 chrV_158460r 9676 essential YER003C 543 + ATTCAACCTTCTGCTCAGAA Q|183|E Q|183|* P|184|A P|184|S PMI40 PhosphoMannose Isomerase 429.0 0 0 0 0 -2.5601820312251307 P29952 0.967860996723175 0.9637759923934937 0.9549559950828552 0.7852781414985657 0.7520060539245605 0.7432536482810974 46.941439847801924 40.0 0.0 yes 3152 chrV_158514 9678 essential YER003C 492 - CCAACAATGTTGCGTAATTC G|171|R G|171|S V|170|L V|170|I PMI40 PhosphoMannose Isomerase 429.0 0 0 0 0 0.2905778897095833 P29952 0.9477360248565674 0.9668909907341005 0.9589639902114868 0.9666330218315125 0.015869993716478348 0.04538480192422867 0.02774009853601456 0.2720356285572052 42.59850231489583 40.0 0.0 no 3153 chrV_158550 9679 essential YER003C 456 - TCATCTGCAATCTCTTGCAA E|159|Q E|159|K D|158|H D|158|N PMI40 PhosphoMannose Isomerase 429.0 0 1 0 0 -0.10662273709595464 P29952 0.97645902633667 0.9644089937210084 0.953902006149292 0.9663879871368408 0.11598788946866988 0.11699075996875764 0.8660935163497925 0.3986639082431793 47.10321367430186 40.0 0.0 no 3154 chrV_158676r 9683 essential YER003C 327 + GCACATCCCGACAAAGCCTT H|111|D H|111|Y A|110|G A|110|V PMI40 PhosphoMannose Isomerase 429.0 1 Series([], Name: modification, dtype: object) 0 0 0 -2.9603715458507995 P29952 0.9914770126342772 0.9916279911994934 0.9672009944915771 0.9664270281791688 0.0 0.0 0.0 0.0 54.335780731858854 55.00000000000001 0.0 yes 3155 chrV_158781 9687 essential YER003C 225 - TCCTTACCTAACATGGCAGA K|81|N silent|AAG>AAA|K|81 D|82|H D|82|N PMI40 PhosphoMannose Isomerase 429.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.03137537027483127 P29952 0.9430890083312988 0.9559190273284912 0.96840500831604 0.3914313614368439 0.11938690394163133 0.4892058372497559 49.8534284144547 45.0 0.0 no 3156 chrV_158874 9693 essential YER003C 132 - CCCATCCATAACTCTGCATA M|50|I M|50|I G|51|R G|51|S PMI40 PhosphoMannose Isomerase 429.0 0 0 0 0 -0.7672849901265989 P29952 0.9849619865417479 0.9849619865417479 0.9727219939231871 0.9916149973869324 0.0 0.0 0.0 0.0 51.39873973614964 45.0 0.0 no 3157 chrV_158900 9695 essential YER003C 106 - ATCTTGTTCAATTTGAACAG D|42|H D|42|N PMI40 PhosphoMannose Isomerase 429.0 0 0 0 0 0.7175752373414263 P29952 0.9559190273284912 0.96840500831604 0.04706714302301407 0.3189519345760345 37.81308175711792 30.0 0.0 no 3158 chrV_158973r 9698 essential YER003C 30 + GGCTACCAACAATACGACTG silent|GGC>GGG|G|11 silent|GGC>GGT|G|11 Y|12|* silent|TAC>TAT|Y|12 PMI40 PhosphoMannose Isomerase 429.0 0 0 0 0 -5.272424149177253 P29952 45.36850985887765 50.0 0.0 yes 3159 chrV_159092 9700 essential YER003C 7 - ATCTAACCTGAACAGCTTGT D|9|H D|9|N R|7|S silent|AGG>AGA|R|7 PMI40 PhosphoMannose Isomerase 429.0 0 0 0 0 0.6441312673277979 P29952 0.965224027633667 0.97645902633667 0.9386019706726074 0.11835437268018725 0.4738190174102783 0.02394706010818481 45.79754449860485 40.0 0.0 no 3160 chrV_162872 9704 essential YER006W 149 + TCCTTCTAACTTTCCTTATA P|51|R P|51|L P|51|A P|51|S NUG1 NUclear GTPase 520.0 0 1 0 0 0.5994005704269921 P40010 0.034645378589630134 0.017500199377536774 0.055785439908504486 0.037952721118927 45.46659949613435 30.0 1.0 no 3161 chrV_162885r 9705 essential YER006W 165 - TCTAAGATCTTAGCCTTATA E|62|Q E|62|K NUG1 NUclear GTPase 520.0 0 1 0 0 0.3654202707692055 P40010 0.5855399966239929 0.8730157017707825 42.175170297984096 30.0 1.0 no 3162 chrV_162950 9707 essential YER006W 227 + GCTTGCCAAACAACAACGAT L|77|V L|77|F A|78|G A|78|V NUG1 NUclear GTPase 520.0 0 0 0 0 -0.3883243933589072 P40010 0.16607633233070376 0.035344917327165604 0.12558510899543762 0.09978784620761873 44.14045974706585 45.0 1.0 no 3163 chrV_162988r 9709 essential YER006W 268 - TGCATCAACGCCTTGTTCCT A|96|P A|96|T D|95|H D|95|N NUG1 NUclear GTPase 520.0 0 0 0 0 -2.8970336097317766 P40010 0.27096983790397644 0.5631399154663086 0.10142266005277634 0.15627188980579376 55.247775650580756 50.0 1.0 yes 3164 chrV_163284r 9711 essential YER006W 564 - TTTCTTGATCTTGTACTCTC R|194|T R|194|K NUG1 NUclear GTPase 520.0 0 0 0 0 -0.29083148730907715 P40010 0.017975285649299618 0.5166976451873779 45.15906698467194 35.0 1.0 no 3165 chrV_163321 9714 essential YER006W 598 + TCTTACAAAGTCAGGGTAAA silent|GTC>GTG|V|200 silent|GTC>GTT|V|200 Q|202|E Q|202|* NUG1 NUclear GTPase 520.0 0 0 0 0 -0.8140313604083694 P40010 1.0 39.176998325624204 35.0 1.0 no 3166 chrV_163604 9720 essential YER006W 881 + ATCTGTTATCAACGCTCTTT S|295|C S|295|F NUG1 NUclear GTPase 520.0 0 0 0 0 0.5013305134519331 P40010 0.0 0.0 45.51287517164923 35.0 1.0 no 3167 chrV_163656r 9724 essential YER006W 936 - ACACCTGCTTCATTACCGAC G|318|A G|318|D V|319|L V|319|I NUG1 NUclear GTPase 520.0 0 1 0 0 -0.6127177792047058 P40010 0.0 0.0 0.17242906987667084 0.3325980305671692 51.6687837901577 50.0 1.0 no 3168 chrV_163749r 9726 essential YER006W 1029 - GATCTTTTCTTATTTTCGCT R|349|T R|349|K NUG1 NUclear GTPase 520.0 0 0 0 0 0.15550412850381487 P40010 0.4405618906021118 1.0 45.009940669947746 30.0 1.0 no 3169 chrV_163836r 9728 essential YER006W 1116 - AACATTAAGACAGCTGGATA M|378|I M|378|I NUG1 NUclear GTPase 520.0 0 0 0 0 -0.008817181039134956 P40010 0.0937306210398674 0.0937306210398674 39.41865030738478 35.0 1.0 no 3170 chrV_169106 9732 essential YER008C 2693 - TGTCCCATTCATTTAGTAAC D|904|H D|904|N W|903|C W|903|* SEC3 SECretory 1336.0 0 0 0 0 0.4109673343608993 P33332 0.9486550092697144 0.956179976463318 0.8858469724655151 0.0327138788998127 0.09865240007638933 0.0 45.220928426820706 35.0 0.0 no 3171 chrV_169525 9736 essential YER008C 2274 - TTCAATTGGTTTTCCATCCA L|764|F silent|TTG>TTA|L|764 SEC3 SECretory 1336.0 0 0 0 0 0.493756970033534 P33332 0.9587849974632264 0.0 48.51567607845822 35.0 0.0 no 3172 chrV_169546 9737 essential YER008C 2253 - GGCAAGTTCTTCTCTCTTAT L|757|F silent|TTG>TTA|L|757 SEC3 SECretory 1336.0 0 0 0 0 0.7570674326689324 P33332 0.9587849974632264 0.0 49.574981515099815 40.0 0.0 no 3173 chrV_169568 9738 essential YER008C 2231 - GACATTCTAATAACTGATTT C|750|S C|750|Y E|749|Q E|749|K SEC3 SECretory 1336.0 0 0 0 0 1.0365512269586772 P33332 0.9421560168266296 0.9290120005607604 0.956179976463318 0.9475290179252625 0.5526249408721924 0.9404807686805724 0.5305576324462891 1.0 35.32116666432938 25.0 0.0 no 3174 chrV_169569 9739 essential YER008C 2230 - ACATTCTAATAACTGATTTA C|750|S C|750|Y E|749|Q E|749|K SEC3 SECretory 1336.0 0 0 0 0 0.3946613342058005 P33332 0.9421560168266296 0.9290120005607604 0.956179976463318 0.9475290179252625 0.5526249408721924 0.9404807686805724 0.5305576324462891 1.0 33.61100500577237 20.0 0.0 no 3175 chrV_169770 9743 essential YER008C 2029 - GTCATTGACCTTGTCTTCGT D|683|H D|683|N SEC3 SECretory 1336.0 0 0 0 0 0.8883048726750502 P33332 0.9486550092697144 0.956179976463318 0.10399053990840912 0.4143950641155243 52.66607095144821 45.0 0.0 no 3176 chrV_169771 9744 essential YER008C 2028 - TCATTGACCTTGTCTTCGTA D|683|H D|683|N SEC3 SECretory 1336.0 0 0 0 0 0.09539392598257336 P33332 0.9486550092697144 0.956179976463318 0.10399053990840912 0.4143950641155243 49.29590881542947 40.0 0.0 no 3177 chrV_169887 9749 essential YER008C 1912 - ACTATCAGCATCGTCTTCAA S|644|T S|644|N D|643|H D|643|N SEC3 SECretory 1336.0 0 1 0 0 -0.6651634564164608 P33332 0.9512869715690612 0.9536849856376648 0.9486550092697144 0.956179976463318 0.7570284605026245 0.3746810257434845 0.032096829265356064 0.08321794122457504 46.895532107664735 40.0 0.0 no 3178 chrV_169999 9751 essential YER008C 1800 - TCAGATTCGTTATTCTCTTC E|607|Q E|607|K SEC3 SECretory 1336.0 0 1 0 0 0.3142867376205233 P33332 0.956179976463318 0.9475290179252625 0.551105260848999 0.8513614535331726 44.6078411113749 35.0 0.0 no 3179 chrV_170003 9752 essential YER008C 1796 - ATTCGTTATTCTCTTCCGGA E|605|Q E|605|K SEC3 SECretory 1336.0 0 1 0 0 -0.09582969208607016 P33332 0.956179976463318 0.9475290179252625 0.5694375038146973 0.8848954439163208 49.753371975505104 40.0 0.0 no 3180 chrV_170018r 9753 essential YER008C 1778 + TTCGCAGAAATTAATCCTTC S|594|W S|594|L Q|595|E Q|595|* SEC3 SECretory 1336.0 0 0 0 0 0.010923507570856555 P33332 0.9288619756698608 0.9298099875450134 0.9590039849281312 1.0 41.159541426730364 35.0 0.0 no 3181 chrV_170254 9759 essential YER008C 1545 - TCAACTTTGGCAATATTTAG E|522|Q E|522|K V|521|L V|521|I SEC3 SECretory 1336.0 0 0 0 0 0.473546062817808 P33332 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.2519897222518921 0.18588998913764954 0.5159694552421571 0.5040291547775269 38.19895978149725 30.0 0.0 no 3182 chrV_170654r 9766 essential YER008C 1142 + CCAACGACAACTCGAAGAAG Q|382|E Q|382|* R|383|G R|383|* SEC3 SECretory 1336.0 0 0 0 0 0.2716150059192046 P33332 0.9590039849281312 0.8994590044021606 0.7783020734786987 0.3535141348838806 40.66137072451414 50.0 0.0 no 3183 chrV_170999r 9776 essential YER008C 797 + GACAAACACTACCCAATCGG T|267|R T|267|I N|268|K silent|AAC>AAT|N|268 SEC3 SECretory 1336.0 0 0 0 0 0.14576331203902246 P33332 0.9476869702339172 0.9472420215606691 0.9439849853515624 0.43130195140838623 0.19239753484725952 0.8984759449958801 45.08385653615966 50.0 0.0 no 3184 chrV_171002r 9777 essential YER008C 794 + CACGACAAACACTACCCAAT T|266|R T|266|M T|267|R T|267|I SEC3 SECretory 1336.0 0 0 0 0 -0.6145711671880246 P33332 0.9476869702339172 0.9502379894256592 0.9476869702339172 0.9472420215606691 0.117921844124794 0.025749266147613525 0.43130195140838623 0.19239753484725952 43.687506693955136 45.0 0.0 no 3185 chrV_171125r 9779 essential YER008C 671 + TGTCCCTGAATTGGTCAATT silent|GTC>GTG|V|225 silent|GTC>GTT|V|225 P|226|A P|226|S SEC3 SECretory 1336.0 0 0 0 1 -0.485617147615921 P33332 0.9562489986419678 0.9498909711837769 0.0 0.0 3.136759996414185 3.4727799892425537 1.521649956703186 1.8089100122451784 48.061566582029116 40.0 0.0 no 3186 chrV_171484 9785 essential YER008C 315 - ACATGTGTAATATAATTATT V|112|L V|112|I SEC3 SECretory 1336.0 0 0 0 0 0.10694161357194094 P33332 0.9539830088615416 0.9574310183525084 0.0 0.0 -0.9061599969863892 -0.22585999965667725 31.47275690063589 15.0 0.0 no 3187 chrV_171649r 9789 essential YER008C 147 + TCCGCACCACCTGTTTCTGG silent|TCC>TCG|S|50 silent|TCC>TCT|S|50 S|50|C S|50|F SEC3 SECretory 1336.0 0 0 0 1 -0.2468443080858264 P33332 0.945252001285553 0.9294660091400146 0.07542487233877182 0.11324548721313475 59.67379728642669 60.0 0.0 no 3188 chrV_171652r 9790 essential YER008C 144 + TCTTCCGCACCACCTGTTTC S|49|C S|49|F S|50|C S|50|F SEC3 SECretory 1336.0 0 0 0 0 -0.05811290812060119 P33332 0.945252001285553 0.9294660091400146 0.945252001285553 0.9294660091400146 0.06340668350458145 0.06854655593633653 0.07542487233877182 0.11324548721313475 58.944537160267494 55.00000000000001 0.0 no 3189 chrV_172300 9794 essential YER009W 185 + CCAACATCGTATCACTACTT Q|63|E Q|63|* H|64|D H|64|Y NTF2 Nuclear Transport Factor 125.0 0 1 0 0 -0.6748975316821748 P33331 0.6315399408340454 0.0 0.0 0.6695659756660461 4.7359957695007315 -0.3955000042915344 45.30407327400758 40.0 1.0 no 3190 chrV_172338r 9796 essential YER009W 226 - GACTAAGACATCGCCATTTG V|82|L V|82|I NTF2 Nuclear Transport Factor 125.0 0 0 0 0 -0.6818519450926431 P33331 0.012984506785869598 0.20743416249752045 3.6056940555572514 1.809000015258789 45.15604328193525 45.0 1.0 no 3191 chrV_177883 9799 essential YER012W 48 + TCTTCTAAGGCAGTCACAAG S|17|C S|17|F S|18|C S|18|F PRE1 PRoteinase yscE 198.0 0 1 0 0 -0.8668007776790572 P22141 0.938103973865509 0.9208130240440368 0.9634199738502502 0.9436050057411194 0.021522816270589832 0.008812826126813889 0.004863728769123554 0.0036596402060240507 -1.6496399641036987 1.0863800048828125 45.67555622558354 45.0 1.0 no 3192 chrV_178063r 9801 essential YER012W 231 - ACAAAACTAGATACTGCTTG V|84|L V|84|I S|82|T S|82|N PRE1 PRoteinase yscE 198.0 0 1 0 0 -0.19312617408979588 P22141 0.9333149790763856 0.9412109851837158 0.9317610263824464 0.9360769987106324 0.13189716637134552 0.8482242226600647 0.4724518358707428 0.929071307182312 1.892300009727478 6.064333915710449 37.25622955803635 35.0 1.0 no 3193 chrV_177974r 9802 essential YER012W 142 - AACGGTGTCACCAGCTTCAC V|54|L V|54|I PRE1 PRoteinase yscE 198.0 0 0 0 0 -0.24637589940773816 P22141 0.9343010187149048 0.942196011543274 0.24928735196590426 0.3251082003116608 -0.997730016708374 -0.6893360018730164 -0.5127999782562256 -0.4551999866962433 53.245440410667975 55.00000000000001 1.0 no 3194 chrV_178100r 9804 essential YER012W 268 - TCTTCTCGACCTAATTGACT R|96|T R|96|K R|95|T R|95|K PRE1 PRoteinase yscE 198.0 0 0 0 0 0.07760912648916378 P22141 0.913004994392395 0.9405699968338012 0.915979027748108 0.9435449838638306 0.595086932182312 1.0 0.0 0.0 0.1393599957227707 0.029759999364614487 0.8688820004463196 0.4745739996433258 0.0004480000061448664 -0.05885599926114082 46.251256582131184 40.0 1.0 no 3195 chrV_178123r 9805 essential YER012W 291 - ATCAATACGTTGACTTGGTA L|103|F silent|TTG>TTA|L|103 PRE1 PRoteinase yscE 198.0 0 0 0 0 0.07708214153784909 P22141 0.9538249969482422 0.10133236646652223 42.022235918001684 35.0 1.0 no 3196 chrV_179119r 9813 essential YER013W 281 - GGACGAATTCAGTCACAACA V|100|L V|100|I PRP22 Pre-mRNA Processing 1145.0 0 0 0 0 -1.751088382685439 P24384 0.7615177035331726 0.4649986922740936 43.673338129906256 45.0 1.0 no 3197 chrV_179179r 9814 essential YER013W 341 - GCATCAAGTTCAGTTGTTCC M|120|I M|120|I L|119|F silent|TTG>TTA|L|119 PRP22 Pre-mRNA Processing 1145.0 0 0 0 0 0.6352675313678227 P24384 0.19644638895988464 0.19644638895988464 0.7151240110397339 51.130298986112784 45.0 1.0 no 3198 chrV_179300r 9816 essential YER013W 462 - ATCTTTGCTTCTATCTTTGC K|160|N silent|AAG>AAA|K|160 PRP22 Pre-mRNA Processing 1145.0 0 0 0 0 0.2485723270309256 P24384 0.5518954992294312 47.7810172766844 35.0 1.0 no 3199 chrV_179292r 9817 essential YER013W 454 - TTCTATCTTTGCTGGTATCT E|158|Q E|158|K K|156|N silent|AAG>AAA|K|156 PRP22 Pre-mRNA Processing 1145.0 0 0 0 0 -0.4311576245880593 P24384 0.5480709075927734 0.8747342228889465 0.357933908700943 48.011454396813576 35.0 1.0 no 3200 chrV_179617r 9826 essential YER013W 779 - CACTTTCAGTATTTCTTTTC S|266|T S|266|N E|265|Q E|265|K PRP22 Pre-mRNA Processing 1145.0 0 0 0 0 0.3469553106610785 P24384 0.5711031556129456 0.5716354846954346 0.54218989610672 0.8202454447746277 42.54459356475644 30.0 1.0 no 3201 chrV_179735 9827 essential YER013W 894 + ATTCGCCAACTAATTGCCAG R|300|G R|300|C silent|CGC>CGG|R|300 silent|CGC>CGT|R|300 PRP22 Pre-mRNA Processing 1145.0 0 0 0 0 0.7691733676061752 P24384 0.034318696707487106 0.005192652344703674 47.986243343052884 45.0 1.0 no 3202 chrV_179814r 9832 essential YER013W 976 - ATCTCTTTTCGCGGTCAAAT D|332|H D|332|N R|331|T R|331|K PRP22 Pre-mRNA Processing 1145.0 0 1 0 0 0.5358140705063943 P24384 0.1340751051902771 0.4219285547733307 0.5342337489128113 0.8855815529823303 46.80894350502536 40.0 1.0 no 3203 chrV_179823r 9833 essential YER013W 985 - ACTGCCGTCATCTCTTTTCG S|335|T S|335|N G|334|A G|334|D PRP22 Pre-mRNA Processing 1145.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.3786802102271846 P24384 0.5765877962112427 0.4958391487598419 0.8682445287704468 0.6354756355285645 53.667594077901704 50.0 1.0 no 3204 chrV_180189 9839 essential YER013W 1348 + ACCAGCTGATTGTTACTGAA Q|451|E Q|451|* N|450|K silent|AAC>AAT|N|450 PRP22 Pre-mRNA Processing 1145.0 0 0 0 0 -1.5491850630702932 P24384 1.0 0.9698715209960938 45.987716322467286 40.0 1.0 no 3205 chrV_180190 9842 essential YER013W 1349 + CCAGCTGATTGTTACTGAAT Q|451|E Q|451|* L|452|V silent|CTG>TTG|L|452 PRP22 Pre-mRNA Processing 1145.0 0 0 0 0 -0.7718755864022285 P24384 1.0 0.4160710871219635 45.53270052579353 40.0 1.0 no 3206 chrV_180290r 9843 essential YER013W 1452 - TCAGACCTCATCGCGTATAC E|491|Q E|491|K R|489|S silent|AGG>AGA|R|489 PRP22 Pre-mRNA Processing 1145.0 0 0 0 0 -0.13656216020057907 P24384 1.0 0.4946788847446442 0.0046558198519051075 50.063786461031036 50.0 1.0 no 3207 chrV_180468r 9849 essential YER013W 1630 - TTCAGCCACTCTTTTAGCAA E|550|Q E|550|K A|549|P A|549|T PRP22 Pre-mRNA Processing 1145.0 0 0 0 0 -0.01846523146758617 P24384 0.11097962409257887 0.05241592228412628 0.006991468835622072 0.0059359860606491574 49.59720710528717 40.0 1.0 no 3208 chrV_180500 9850 essential YER013W 1659 + TGCAAAGTTGGCCATGACGT C|554|W silent|TGC>TGT|C|554 PRP22 Pre-mRNA Processing 1145.0 0 0 0 0 -0.2219201516991404 P24384 0.000451009051175788 50.24042584184292 50.0 1.0 no 3209 chrV_180805 9855 essential YER013W 1964 + ACCTGGTAAAACTTTTCCCG P|656|R P|656|L P|656|A P|656|S PRP22 Pre-mRNA Processing 1145.0 0 0 0 0 -2.132770076893936 P24384 0.0016350378282368185 0.001841095625422895 0.01489369571208954 0.055180560797452934 47.72183121461256 45.0 1.0 yes 3210 chrV_180835 9857 essential YER013W 1994 + CTACTCACAGACGCCCCAAA Y|666|* silent|TAC>TAT|Y|666 S|667|* S|667|L PRP22 Pre-mRNA Processing 1145.0 0 0 0 0 -3.0742771158794238 P24384 0.11116939783096312 52.285932222351725 55.00000000000001 1.0 yes 3211 chrV_181079r 9859 essential YER013W 2241 - ACGACTTTTCGACTGCCCTT V|754|L V|754|I V|753|L V|753|I PRP22 Pre-mRNA Processing 1145.0 0 0 0 0 0.6919453543599863 P24384 0.011845799162983894 0.3197673559188843 0.028644153848290443 0.040665827691555016 53.62897703798228 50.0 1.0 no 3212 chrV_180614r 9860 essential YER013W 1776 - ACTGAATATTTTGACATCTC V|599|L V|599|I PRP22 Pre-mRNA Processing 1145.0 0 0 0 0 1.1123769696336698 P24384 0.07423160970211029 0.11922587454319 38.051251579518244 30.0 1.0 no 3213 chrV_192243r 9874 essential YER018C 359 + TGTCCAATTACGCGCACGTT silent|GTC>GTG|V|121 silent|GTC>GTT|V|121 Q|122|E Q|122|* 0 0 0 0 -0.16869785059203266 P40014 0.14847756922245026 51.36953142183734 50.0 0.0 no 3214 chrV_192297r 9877 essential YER018C 305 + AGCAGCCCAATCGCGCGAGC A|103|G A|103|V A|104|G A|104|V 0 0 0 0 -1.5927641957301093 P40014 0.2670670449733734 1.0 0.363174706697464 0.2745877802371979 60.594137888769524 70.0 0.0 no 3215 chrV_192961r 9896 high_effect YER019W 167 - TTGCTCTGAGTCTTTCTTTA A|62|P A|62|T R|61|T R|61|K ISC1 Inositol phosphoSphingolipid phospholipase C 477.0 0 0 0 0 -2.703037765888312 P40015 0.9573720097541808 0.9523990154266356 0.932735025882721 0.955805003643036 0.1760023683309555 0.2966538369655609 0.6088288426399231 0.9334685802459716 48.02263762428737 35.0 1.0 yes 3216 chrV_193025 9899 high_effect YER019W 228 + TCTGACGAGTTGTTGCCCAA S|77|C S|77|F D|78|E silent|GAC>GAT|D|78 ISC1 Inositol phosphoSphingolipid phospholipase C 477.0 0 0 0 0 0.6796134480064405 P40015 0.945252001285553 0.9294660091400146 0.9532920122146606 52.61911897052676 50.0 1.0 no 3217 chrV_193041r 9903 high_effect YER019W 247 - TTCATTACTATCTCCACCAT E|89|Q E|89|K ISC1 Inositol phosphoSphingolipid phospholipase C 477.0 0 0 0 0 -0.17299483706887764 P40015 0.956179976463318 0.9475290179252625 47.778178276933936 35.0 1.0 no 3218 chrV_193086r 9904 high_effect YER019W 292 - CACACACCAGATTTCTTGTA V|104|L V|104|M C|103|S C|103|Y ISC1 Inositol phosphoSphingolipid phospholipase C 477.0 0 1 0 0 0.02370999163952292 P40015 0.9539830088615416 0.9587630033493042 0.9421560168266296 0.9290120005607604 0.7036064267158508 0.23969919979572296 0.9047570824623108 0.09597621113061904 46.50446792611717 40.0 1.0 no 3219 chrV_193165 9907 high_effect YER019W 368 + GTTCCATTCTGGTATTCTGA F|124|L silent|TTC>TTT|F|124 H|125|D H|125|Y ISC1 Inositol phosphoSphingolipid phospholipase C 477.0 0 0 0 0 0.19067457498090928 P40015 0.9387490153312684 0.9473130106925964 0.9489949941635132 0.04009568691253662 0.1860333234071732 1.0 50.288280718826115 40.0 1.0 no 3220 chrV_193307 9919 high_effect YER019W 510 + GCAATCACCGTATTGAACAC A|171|G A|171|V I|172|M silent|ATC>ATT|I|172 ISC1 Inositol phosphoSphingolipid phospholipase C 477.0 0 0 0 0 -1.0641313663814032 P40015 0.9484469890594482 0.9504740238189696 0.9598389863967896 0.1169031485915184 0.013157162815332413 0.0818248987197876 44.597474880583036 45.0 1.0 no 3221 chrV_193405r 9929 high_effect YER019W 611 - CCCAGGCCTGACAAGATCTG W|210|S W|210|* W|210|C W|210|* ISC1 Inositol phosphoSphingolipid phospholipase C 477.0 0 0 0 0 -3.807851793296113 P40015 0.8858469724655151 0.8858469724655151 0.0 0.0 54.995556076449134 60.0 1.0 yes 3222 chrV_193434 9932 high_effect YER019W 637 + GCAGGCTCATTAAGCTTTAC S|213|R silent|AGC>AGT|S|213 L|215|V L|215|F ISC1 Inositol phosphoSphingolipid phospholipase C 477.0 0 0 0 0 0.13823066766926115 P40015 0.9417110085487366 0.9512209892272948 0.9587849974632264 0.3617168664932251 0.2116351276636124 0.026425721123814583 48.730909000634824 45.0 1.0 no 3223 chrV_193516 9935 high_effect YER019W 719 + CCACAAATTTCTCACGCAGG H|241|Q silent|CAC>CAT|H|241 H|241|D H|241|Y ISC1 Inositol phosphoSphingolipid phospholipase C 477.0 0 0 0 0 -0.033269282422765445 P40015 0.9588389992713928 0.9473130106925964 0.9489949941635132 0.02528197877109051 0.03284332528710365 0.8378047943115234 47.584763243063485 50.0 1.0 no 3224 chrV_193606 9938 high_effect YER019W 809 + TCCATTGCAACAATTGCTTA P|271|R P|271|L P|271|A P|271|S ISC1 Inositol phosphoSphingolipid phospholipase C 477.0 0 1 0 0 -0.32036729405621783 P40015 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.08356007188558577 0.8258898854255676 0.7292987704277039 0.2103278785943985 44.72179246054162 35.0 1.0 no 3225 chrV_193607 9940 high_effect YER019W 810 + CCATTGCAACAATTGCTTAA P|271|R P|271|L Q|273|E Q|273|* ISC1 Inositol phosphoSphingolipid phospholipase C 477.0 0 1 0 0 0.5546313289888923 P40015 0.9432820081710817 0.9430609941482544 0.9590039849281312 0.08356007188558577 0.8258898854255676 1.0 42.41890623007629 35.0 1.0 no 3226 chrV_193644 9941 high_effect YER019W 847 + ATTCGCTGCTCAACACATGG S|284|W S|284|L L|285|V silent|CTG>TTG|L|285 ISC1 Inositol phosphoSphingolipid phospholipase C 477.0 0 0 0 0 -1.7298293636386184 P40015 0.9288619756698608 0.9298099875450134 0.9512209892272948 0.0012372916098684072 0.0054589398205280295 1.0 49.158050100479784 50.0 1.0 no 3227 chrV_193679r 9944 high_effect YER019W 885 - TCCAACCTGCATGCCTCATC L|301|F silent|TTG>TTA|L|301 D|302|H D|302|N ISC1 Inositol phosphoSphingolipid phospholipase C 477.0 0 0 0 0 -2.15909007155882 P40015 0.9587849974632264 0.9486550092697144 0.956179976463318 0.0 0.0 0.0 57.17679935527627 55.00000000000001 1.0 yes 3228 chrV_193857r 9953 high_effect YER019W 1063 - AGTCTTCGCACGCTTAACGG K|360|N silent|AAG>AAA|K|360 silent|GCG>GCC|A|359 silent|GCG>GCA|A|359 ISC1 Inositol phosphoSphingolipid phospholipase C 477.0 0 0 0 0 0.13761050804687808 P40015 0.9355990290641784 0.4925543665885925 51.05656020631381 55.00000000000001 1.0 no 3229 chrV_197004r 9955 essential YER021W 59 - CCGCATATTTCTTCTCAGAA A|26|P A|26|T silent|GCG>GCC|A|26 silent|GCG>GCA|A|26 RPN3 Regulatory Particle Non-ATPase 523.0 0 1 0 0 0.9607247640126202 P40016 0.31842195987701416 0.5848206281661987 47.09464434668274 40.0 1.0 no 3230 chrV_197094r 9957 essential YER021W 149 - AACTCCTCCATATATATCTT S|56|T S|56|N R|55|S silent|AGG>AGA|R|55 RPN3 Regulatory Particle Non-ATPase 523.0 0 1 0 0 -0.7794498062226874 P40016 0.22623118758201602 0.051469042897224426 0.007609973661601543 44.145345286572244 30.0 1.0 no 3231 chrV_197095r 9958 essential YER021W 150 - AAACTCCTCCATATATATCT S|56|T S|56|N R|55|S silent|AGG>AGA|R|55 RPN3 Regulatory Particle Non-ATPase 523.0 0 1 0 0 -0.4567684179055828 P40016 0.22623118758201602 0.051469042897224426 0.007609973661601543 42.425653645133366 30.0 1.0 no 3232 chrV_197306r 9964 essential YER021W 361 - GGTCTTTTTCTCAGTGTTTA K|126|N silent|AAG>AAA|K|126 RPN3 Regulatory Particle Non-ATPase 523.0 0 0 0 0 0.5388486004916153 P40016 0.5147780776023865 48.74871484457788 35.0 1.0 no 3233 chrV_197373r 9965 essential YER021W 428 - TACTGTCCCATAAAAACAAC S|149|T S|149|N D|148|H D|148|N RPN3 Regulatory Particle Non-ATPase 523.0 0 0 0 0 0.6438830440976059 P40016 0.5985697507858276 0.5493690967559814 0.021440831944346428 0.16952310502529144 38.29146781279803 35.0 1.0 no 3234 chrV_197582r 9968 essential YER021W 637 - TTTCAAAAACTTCATCATCG L|218|F silent|TTG>TTA|L|218 RPN3 Regulatory Particle Non-ATPase 523.0 0 0 0 0 -0.5788401913013272 P40016 0.09989672154188156 36.00422909271407 30.0 1.0 no 3235 chrV_197730 9970 essential YER021W 782 + CACAGACGTTTCCAGTTCAT T|262|R T|262|I D|263|E silent|GAC>GAT|D|263 RPN3 Regulatory Particle Non-ATPase 523.0 0 0 0 0 1.1115490344156926 P40016 0.06702780723571777 0.06603781878948213 1.0 0.2648000121116638 1.0013999938964844 49.653305320376894 45.0 1.0 no 3236 chrV_197848r 9973 essential YER021W 903 - CCTAAACTCTTGGAATTATG G|308|R G|308|R S|306|T S|306|N RPN3 Regulatory Particle Non-ATPase 523.0 0 0 0 0 -1.6597072537868267 P40016 0.008793799206614494 0.008793799206614494 0.1919779032468796 0.011740821413695812 38.795853525059435 35.0 1.0 no 3237 chrV_197849 9974 essential YER021W 901 + CACATAATTCCAAGAGTTTA H|302|D H|302|Y RPN3 Regulatory Particle Non-ATPase 523.0 0 0 0 0 0.12553146949286453 P40016 0.6300922036170961 0.1724729984998703 39.04700892531434 30.0 1.0 no 3238 chrV_197993r 9976 essential YER021W 1048 - GTCACCTAATTTAACGGCTT D|356|H D|356|N G|355|A G|355|D RPN3 Regulatory Particle Non-ATPase 523.0 0 0 0 0 -0.40799255426996217 P40016 0.013376085087656977 0.3785226941108704 0.08287093788385391 0.004521499387919903 1.4734699726104736 1.1356799602508545 -0.6299999952316284 0.9757200479507446 46.247393711957905 40.0 1.0 no 3239 chrV_197999r 9977 essential YER021W 1054 - TTTCAAGTCACCTAATTTAA L|357|F silent|TTG>TTA|L|357 RPN3 Regulatory Particle Non-ATPase 523.0 0 0 0 0 -0.6190339036906575 P40016 0.01508157607167959 38.039379626965626 25.0 1.0 no 3240 chrV_198947r 9982 essential YER022W 138 - TTTCCTGCAGATTCAGGTAC G|52|A G|52|E G|52|R G|52|R SRB4 Suppressor of RNA polymerase B 687.0 0 0 0 0 -1.7495043031176418 P32569 0.9903749823570251 0.9759219884872437 0.9727219939231871 0.9727219939231871 0.8251364827156067 1.0 0.4944268465042114 0.4944268465042114 50.43807819527864 45.0 1.0 no 3241 chrV_198953r 9983 essential YER022W 144 - TCTGCTTTTCCTGCAGATTC D|55|H D|55|N A|54|P A|54|T SRB4 Suppressor of RNA polymerase B 687.0 0 1 0 0 -0.3956145384166965 P32569 0.9899479746818542 1.0004899501800537 1.0011199712753296 0.9935200214385986 0.034936532378196716 0.14988847076892853 0.3116027414798737 0.6221371293067932 52.98891304211014 45.0 1.0 no 3242 chrV_199098r 9984 essential YER022W 289 - GATCAATTGCTCCAACGGCA L|102|F silent|TTG>TTA|L|102 SRB4 Suppressor of RNA polymerase B 687.0 0 0 0 0 -2.032655299463461 P32569 0.9341800212860109 0.1277865320444107 0.4590399861335754 50.17202715340653 50.0 1.0 yes 3243 chrV_199121 9986 essential YER022W 309 + CCAATCATCTTAAGACAGCG P|104|R P|104|L I|105|M silent|ATC>ATT|I|105 SRB4 Suppressor of RNA polymerase B 687.0 0 0 0 0 -1.5188300337852243 P32569 0.9753050208091736 0.9834169745445251 1.0027899742126465 0.0 0.0 0.025748729705810547 44.14078056001529 45.0 1.0 no 3244 chrV_199527 9992 essential YER022W 715 + CATCAATGTCACCATTTCTT S|240|* S|240|L SRB4 Suppressor of RNA polymerase B 687.0 0 0 0 0 -1.6653029251255969 P32569 0.9056829810142516 0.0 -1.2676000595092771 45.30828659058892 35.0 1.0 no 3245 chrV_199716 9994 essential YER022W 904 + TACAGAACGAACATGACTAT Q|303|E Q|303|* SRB4 Suppressor of RNA polymerase B 687.0 0 0 0 0 -0.6924899801326371 P32569 0.9336990118026732 0.9900503754615784 36.931885701529325 35.0 1.0 no 3246 chrV_199922 9997 essential YER022W 1110 + CACAGTAGTTCAGTGTTCAA H|371|Q silent|CAC>CAT|H|371 SRB4 Suppressor of RNA polymerase B 687.0 0 0 0 0 -0.18601737555292047 P32569 0.933493971824646 0.2861829996109009 -0.4510000050067902 45.718789613966635 40.0 1.0 no 3247 chrV_199959 9998 essential YER022W 1147 + ATTCAGTAAAGAAATTCTTA S|384|* S|384|L SRB4 Suppressor of RNA polymerase B 687.0 0 0 0 0 -0.29140888244812146 P32569 0.9753659963607788 0.3160539269447327 32.03956893375721 20.0 1.0 no 3248 chrV_200156 10001 essential YER022W 1344 + TGCGCTTTGTTGATTTCCTA C|449|W silent|TGC>TGT|C|449 A|450|G A|450|V SRB4 Suppressor of RNA polymerase B 687.0 0 0 0 0 -0.6357538642429541 P32569 0.9663929939270021 0.9919250011444092 0.991150975227356 0.005520090460777283 0.4715075790882111 0.27169573307037354 -0.7789999842643738 0.2825999855995178 5.375800132751465 50.73765568880464 40.0 1.0 no 3249 chrV_200265r 10004 essential YER022W 1456 - GTCTTGTTCATGATTGACAA D|492|H D|492|N SRB4 Suppressor of RNA polymerase B 687.0 0 0 0 0 -0.20299535995282844 P32569 0.9899479746818542 1.0004899501800537 0.011227197013795376 0.0292363204061985 42.711875217358745 35.0 1.0 no 3250 chrV_200291r 10005 essential YER022W 1482 - GCTCTCTTGTCGTTGATTTT R|500|T R|500|K A|501|P A|501|T SRB4 Suppressor of RNA polymerase B 687.0 0 0 0 0 -0.8986310290738915 P32569 0.979092001914978 0.9988390207290648 1.0011199712753296 0.9935200214385986 0.01060516107827425 0.16302131116390228 0.0 0.0 12.383600234985352 7.222400188446045 4.598060131072998 2.4696199893951416 50.52033796252448 40.0 1.0 no 3251 chrV_201184r 10007 essential YER023W 111 - TTACATGTGATAATTTTGGA C|43|S C|43|Y PRO3 PROline requiring 286.0 0 0 0 0 -0.7447277243571351 P32263 0.924465000629425 0.908594012260437 0.0462915264070034 0.006107041612267493 0.20479999482631686 7.561800003051758 36.77501218608239 25.0 1.0 no 3252 chrV_201236r 10010 essential YER023W 163 - GTCGAATGTCTCAACTAGAT D|61|H D|61|N PRO3 PROline requiring 286.0 0 0 0 0 -0.04059646345696072 P32263 0.9349290132522584 0.9486119747161864 0.1173979789018631 0.6357713341712952 42.70942653304286 40.0 1.0 no 3253 chrV_201349r 10012 essential YER023W 276 - AACACTTCTTCGGCCAAAAA silent|GTG>GTC|V|98 silent|GTG>GTA|V|98 V|98|L V|98|M PRO3 PROline requiring 286.0 0 0 0 0 0.15238783540036954 P32263 0.9523900151252748 0.961428999900818 0.26253893971443176 0.016481133177876472 42.6550789669318 40.0 1.0 no 3254 chrV_201403 10014 essential YER023W 327 + CTACTTATTTCCCTGGCTGC L|111|V L|111|F PRO3 PROline requiring 286.0 0 0 0 0 -0.2954502933523893 P32263 0.9369500279426576 0.9490529894828796 0.01631853170692921 0.1109885424375534 55.175261028643654 50.0 1.0 no 3255 chrV_201487r 10016 essential YER023W 414 - CAACCATATCCGTACTTGGC G|144|A G|144|D G|144|R G|144|S PRO3 PROline requiring 286.0 0 1 0 0 -1.7189930770658275 P32263 0.9572569727897644 0.9439510107040404 0.9381110072135924 0.9584969878196716 0.0935475006699562 0.02541770599782467 0.009412775747478008 0.5335915088653564 50.3058241192976 50.0 1.0 no 3256 chrV_201484 10018 essential YER023W 408 + ACACCTGCCAAGTACGGATA P|138|A P|138|S T|137|R T|137|I PRO3 PROline requiring 286.0 0 1 0 0 -0.20425752000206368 P32263 0.9763929843902588 0.9679129719734192 0.9528260231018066 0.9646379947662354 0.6632732152938843 0.06565023958683014 0.003490080591291189 0.005251005291938782 50.70043810162002 50.0 1.0 no 3257 chrV_201646r 10026 essential YER023W 573 - AACATCAAGAGAACAAAAGC M|197|I M|197|I L|196|F silent|TTG>TTA|L|196 PRO3 PROline requiring 286.0 0 0 0 0 0.7363885526488109 P32263 0.9431359767913818 0.9431359767913818 0.946524977684021 1.0 1.0 0.06106475740671158 1.0784000158309937 1.0784000158309937 0.03440000116825104 0.19520001113414764 0.19520001113414764 1.534980058670044 33.441271693522594 35.0 1.0 no 3258 chrV_201705r 10028 essential YER023W 632 - ACTCCTTACTCTCTTGTAAT E|217|Q E|217|K E|217|D silent|GAG>GAA|E|217 PRO3 PROline requiring 286.0 0 1 0 0 -0.14163200041330393 P32263 0.9533889889717102 0.9383190274238586 0.9420210123062134 0.5532621741294861 0.8479349613189697 0.5975363254547119 -0.22271999716758728 -0.2546800076961517 0.5576599836349487 46.5156486408469 35.0 1.0 no 3259 chrV_205275r 10030 essential YER025W 27 - TTACCGTTGATAATAATGCT G|15|A G|15|D G|15|R G|15|S GCD11 General Control Derepressed 527.0 0 0 0 0 -0.6602095893750692 P32481 40.089339327186345 30.0 1.0 no 3260 chrV_205399r 10033 essential YER025W 151 - GTCTTCTTCCAAGCCAGTGA D|57|H D|57|N E|56|Q E|56|K GCD11 General Control Derepressed 527.0 0 1 0 0 -2.3001691044629187 P32481 55.79965575739567 50.0 1.0 yes 3261 chrV_205522r 10036 essential YER025W 274 - TTGCCTGTTGATAATTTCGG R|97|S silent|AGG>AGA|R|97 R|97|T R|97|K GCD11 General Control Derepressed 527.0 0 0 0 0 -1.2307650516230386 P32481 0.004808472003787756 0.006178452167659998 0.28085219860076904 45.789733132338654 40.0 1.0 no 3262 chrV_205548 10038 essential YER025W 297 + ACAATAAACATCGGTACCAT T|100|R T|100|I GCD11 General Control Derepressed 527.0 0 0 0 0 0.21787985668916204 P32481 0.02027326077222824 0.08195259422063828 40.285524220635644 35.0 1.0 no 3263 chrV_205593 10044 essential YER025W 342 + ACAGTAGTTAGGGCTATTTC T|115|R T|115|I GCD11 General Control Derepressed 527.0 0 0 0 0 -1.137028647561076 P32481 0.0014573325170204046 0.050341874361038215 46.8291083423909 40.0 1.0 no 3264 chrV_205716r 10047 essential YER025W 468 - GATCTATAACAATCAGGTTC R|162|T R|162|K GCD11 General Control Derepressed 527.0 0 0 0 0 0.3924286501907439 P32481 0.4429839551448822 0.4231237471103668 39.20796559686124 35.0 1.0 no 3265 chrV_206094r 10058 essential YER025W 846 - TACTTCAACTGAGCGGATAT K|288|N silent|AAG>AAA|K|288 L|287|F silent|TTG>TTA|L|287 GCD11 General Control Derepressed 527.0 0 0 0 0 -0.5191299053260304 P32481 0.2968197762966156 0.6335688829421997 0.4532000124454498 43.469371919277314 40.0 1.0 no 3266 chrV_206208 10059 essential YER025W 957 + TCATTTGATGTTAATAAGCC S|320|* S|320|L GCD11 General Control Derepressed 527.0 0 0 0 0 0.2315161875427841 P32481 0.0 39.492632013468665 30.0 1.0 no 3267 chrV_206187r 10060 essential YER025W 939 - GAACGAATAACAATTAACCT R|319|P R|319|H GCD11 General Control Derepressed 527.0 0 0 0 0 -2.8435332838583984 P32481 0.0 0.0 34.53991704592602 30.0 1.0 yes 3268 chrV_206406 10064 essential YER025W 1155 + GACTTGAAGTTTGCTGTTCC D|386|E silent|GAC>GAT|D|386 GCD11 General Control Derepressed 527.0 0 0 0 0 -0.15842053717679594 P32481 0.9039385318756104 49.03471937748218 45.0 1.0 no 3269 chrV_206386r 10065 essential YER025W 1138 - GTCATTTTGTTCGGCAAATA D|386|H D|386|N GCD11 General Control Derepressed 527.0 0 0 0 0 0.16278395849276395 P32481 0.11585657298564912 0.26382628083229065 43.588327734300044 35.0 1.0 no 3270 chrV_206425r 10067 essential YER025W 1177 - ACCAACACCAATCAGACCAC G|399|R G|399|S G|399|A G|399|D GCD11 General Control Derepressed 527.0 0 1 0 0 -4.3504981725424665 P32481 0.07885552942752838 0.07706737518310547 0.11933089792728425 0.014908066019415855 48.38440495630988 50.0 1.0 yes 3271 chrV_206424r 10069 essential YER025W 1176 - CCAACACCAATCAGACCACC G|399|R G|399|S V|398|L V|398|I GCD11 General Control Derepressed 527.0 0 1 0 0 -2.0757038695900367 P32481 0.07885552942752838 0.07706737518310547 0.06580831110477448 0.3623862862586975 51.34716698394084 55.00000000000001 1.0 yes 3272 chrV_212845 10073 essential YER029C 313 - TCTCACTAGTCTTTCCTTCT silent|GTG>GTC|V|110 silent|GTG>GTA|V|110 R|111|T R|111|K SMB1 SmB/B' homolog 196.0 0 0 0 1 0.13017178846488706 P40018 0.7097122669219971 1.0 52.604188684513986 40.0 0.0 no 3273 chrV_212875 10074 essential YER029C 283 - CGGCTTATCCTCCACCACTG K|100|N silent|AAG>AAA|K|100 SMB1 SmB/B' homolog 196.0 0 0 0 0 -1.6981323371503785 P40018 0.22131691873073575 57.944568587570075 60.0 0.0 no 3274 chrV_213114r 10080 essential YER029C 41 + CCTTATTGATTATAAGCTGA L|15|V L|15|F SMB1 SmB/B' homolog 196.0 0 0 0 0 0.3933191197289384 P40018 0.0 0.0 1.6211999654769895 0.2372000068426132 40.49318934006021 30.0 0.0 no 3275 chrV_223917r 10086 essential YER036C 1260 + GACTCACGTATTGCCCTTGT D|421|E silent|GAC>GAT|D|421 S|422|* S|422|L ARB1 ATP-binding cassette protein involved in Ribosome Biogenesis 610.0 0 0 0 0 -0.5245637123046252 P40024 0.9532920122146606 0.9298099875450134 0.09046172350645064 0.00376143935136497 54.77352893975701 50.0 0.0 no 3276 chrV_223963 10088 essential YER036C 1217 - GTTCGTACAAGTTTTCGGAT E|412|Q E|412|K ARB1 ATP-binding cassette protein involved in Ribosome Biogenesis 610.0 0 0 0 0 -1.4376780297161404 P40024 0.956179976463318 0.9475290179252625 0.2283740192651749 1.0 45.62176376443818 40.0 0.0 no 3277 chrV_224306 10095 essential YER036C 874 - AGCTCTCATGTCAATCATAT A|298|P A|298|T R|297|T R|297|K ARB1 ATP-binding cassette protein involved in Ribosome Biogenesis 610.0 0 1 0 0 0.9994149137011524 P40024 0.9573720097541808 0.9523990154266356 0.932735025882721 0.955805003643036 0.31309962272644043 0.6694647073745728 0.6674460172653198 0.9594846963882446 -1.0512000322341921 0.9276000261306764 44.895468706096096 35.0 0.0 no 3278 chrV_224507 10099 essential YER036C 673 - CCATCCACCAGACATATCTT W|231|S W|231|* G|230|A G|230|E ARB1 ATP-binding cassette protein involved in Ribosome Biogenesis 610.0 0 0 0 0 -4.309939540178797 P40024 0.8858469724655151 0.9499930143356324 0.9438679814338684 0.0 0.0 0.0 1.0046000480651855 51.455436076072324 45.0 0.0 yes 3279 chrV_224634 10102 essential YER036C 546 - GGCTCTAATAACTCGGACTC E|188|D silent|GAG>GAA|E|188 E|188|Q E|188|K ARB1 ATP-binding cassette protein involved in Ribosome Biogenesis 610.0 0 0 0 0 -0.25733970526507705 P40024 0.94931298494339 0.956179976463318 0.9475290179252625 0.6306531429290771 0.5762356519699097 0.8540756106376648 47.04892451973467 50.0 0.0 no 3280 chrV_224922r 10110 essential YER036C 255 + TCTGTTTCTTTACTGTTCCA S|86|C S|86|F ARB1 ATP-binding cassette protein involved in Ribosome Biogenesis 610.0 0 0 0 0 0.06210423271227871 P40024 0.945252001285553 0.9294660091400146 0.020619980990886688 0.019300853833556172 49.4622022951205 35.0 0.0 no 3281 chrV_225152 10114 essential YER036C 28 - AGCTTTCTTAGCATCTCTCT A|16|P A|16|T K|14|N silent|AAG>AAA|K|14 ARB1 ATP-binding cassette protein involved in Ribosome Biogenesis 610.0 0 0 0 0 0.3817563275688245 P40024 0.9573720097541808 0.9523990154266356 0.9355990290641784 0.20196013152599332 0.05313214659690857 52.131650093207156 40.0 0.0 no 3282 chrV_227250 10116 essential YER038C 983 - GGACCTTAAAACACAGTCTA V|334|L V|334|I K|333|N silent|AAG>AAA|K|333 0 0 0 0 -0.8226000877478574 P40026 0.1402575522661209 0.9989692568778992 0.553963840007782 42.52758557041028 40.0 0.0 no 3283 chrV_227559 10121 essential YER038C 674 - GCGATCTACTACTACCAAAC silent|TCG>TCC|S|231 silent|TCG>TCA|S|231 R|230|T R|230|K 0 0 0 0 0.14834684551728927 P40026 0.27349799871444697 0.6135731339454651 44.03679115944697 45.0 0.0 no 3284 chrV_227613r 10122 essential YER038C 617 + CTGCCATTACGAGCAATTGA C|207|W silent|TGC>TGT|C|207 H|208|D H|208|Y 0 0 0 0 -0.4967582084768406 P40026 0.05138427764177322 0.5764052271842957 0.1033029407262802 47.214229419506246 45.0 0.0 no 3285 chrV_227656 10123 essential YER038C 577 - ATCTTTATATTTATCTGATA D|199|H D|199|N 0 0 0 0 -0.5325768155744837 P40026 0.0 0.0 34.348584564224375 15.0 0.0 no 3286 chrV_227691 10124 essential YER038C 542 - CCACATCCAAATAAATTTCT V|187|L V|187|M silent|GTG>GTC|V|187 silent|GTG>GTA|V|187 0 0 0 0 0.9651560501737306 P40026 0.9853439331054688 0.34445711970329285 39.52397761276762 30.0 0.0 no 3287 chrV_227873r 10126 essential YER038C 357 + CCTTTAAAAATTTTCAATCT P|120|R P|120|L 0 0 0 0 0.17679453106939913 P40026 0.4189512729644776 0.24116206169128415 34.12602386016226 20.0 0.0 no 3288 chrV_227933 10128 essential YER038C 300 - TCCTCATCCTCGTTATTACT E|106|D silent|GAG>GAA|E|106 E|107|Q E|107|K 0 1 0 0 -0.13903717278436706 P40026 51.38892803014546 40.0 0.0 no 3289 chrV_228092 10134 essential YER038C 141 - TCAGGATCACTAATAAAGTT E|54|Q E|54|K 0 0 0 0 0.4480357469513247 P40026 0.3476106822490692 0.4400056004524231 36.98363113897233 30.0 0.0 no 3290 chrV_228156r 10136 essential YER038C 74 + TCCTTTGATACCGACTAGTG P|26|R P|26|L P|26|A P|26|S 0 0 0 0 0.3691913312801071 P40026 47.993931874507844 45.0 0.0 no 3291 chrV_236189 10139 essential YER043C 911 - CATCAATTTCGATATCGAAA D|310|H D|310|N SAH1 S-Adenosyl-l-Homocysteine hydrolase 449.0 0 0 0 0 0.3199719841298929 P39954 0.965224027633667 0.97645902633667 0.003459515515714884 0.015086630359292032 36.091461037655726 30.0 0.0 no 3292 chrV_236291 10141 essential YER043C 809 - TAACGAAAACTTGACCAATG V|276|L V|276|I SAH1 S-Adenosyl-l-Homocysteine hydrolase 449.0 0 0 0 0 -0.04199205540302259 P39954 0.9754850268363952 0.983153998851776 0.022052522748708725 0.802794873714447 35.086027124621296 35.0 0.0 no 3293 chrV_236292 10142 essential YER043C 808 - AACGAAAACTTGACCAATGT V|276|L V|276|I SAH1 S-Adenosyl-l-Homocysteine hydrolase 449.0 0 0 0 0 -0.7259911214347051 P39954 0.9754850268363952 0.983153998851776 0.022052522748708725 0.802794873714447 37.54023230823231 35.0 0.0 no 3294 chrV_236397 10149 essential YER043C 703 - ACGAGCACCCATTCCTCTTA R|241|P R|241|H A|240|P A|240|T SAH1 S-Adenosyl-l-Homocysteine hydrolase 449.0 0 0 0 0 -1.1963804622317693 P39954 0.9368820190429688 0.9760839939117432 0.9770879745483398 0.9687960147857666 0.16626109182834625 0.33963078260421753 0.06986351311206818 0.013160408474504948 5.3418002128601065 2.752000093460083 55.57533311295958 50.0 0.0 no 3295 chrV_236442 10151 essential YER043C 658 - ATCACCGTAACCAGCAACAA D|226|H D|226|N G|225|A G|225|D SAH1 S-Adenosyl-l-Homocysteine hydrolase 449.0 0 1 0 0 -6.025794562386341 P39954 0.9897220134735109 1.0002599954605105 0.9913370013237 0.9792760014533995 0.010723637416958807 0.019974874332547188 0.0 0.0 46.594391999431714 45.0 0.0 yes 3296 chrV_236628 10157 essential YER043C 472 - AACACCGGTGGTAGTTTCTT V|164|L V|164|I G|163|A G|163|D SAH1 S-Adenosyl-l-Homocysteine hydrolase 449.0 0 0 0 0 -1.2446863928820329 P39954 0.9940739870071412 1.0010499954223633 0.9901490211486816 0.9780880212783812 0.01360872108489275 0.13206297159194946 0.0069304960779845715 0.010579990223050116 0.3587999939918518 -0.07840000092983246 50.50504905995575 45.0 0.0 no 3297 chrV_236660 10158 essential YER043C 440 - AGCAGTCTTCCAGCATTTCA C|153|S C|153|Y D|152|H D|152|N SAH1 S-Adenosyl-l-Homocysteine hydrolase 449.0 0 0 0 0 -0.16258502214066686 P39954 0.9601609706878662 0.9424200057983398 0.965224027633667 0.97645902633667 0.005621465854346752 0.003974184859544039 0.11253311485052107 0.4767495393753052 1.2222000360488892 18.487199783325195 54.740208103852304 45.0 0.0 no 3298 chrV_236793 10163 essential YER043C 307 - TTCTTCAGTTTCACCCTTCC E|109|Q E|109|K E|108|Q E|108|K SAH1 S-Adenosyl-l-Homocysteine hydrolase 449.0 0 0 0 0 -0.6551254566451616 P39954 0.9840490221977234 0.972000002861023 0.97645902633667 0.9644089937210084 0.3499807119369507 0.11256032437086104 0.18242236971855166 0.1474209725856781 55.99251270966619 45.0 0.0 no 3299 chrV_237017r 10173 essential YER043C 80 + ACATGAAATGCCAGGTTTGA H|28|D H|28|Y SAH1 S-Adenosyl-l-Homocysteine hydrolase 449.0 0 0 0 0 -0.4839759664877025 P39954 0.9669790267944336 0.9671300053596495 0.6068083047866821 0.038057513535022736 1.3767999410629272 0.1897999942302704 44.644619478686316 40.0 0.0 no 3300 chrV_237048 10174 essential YER043C 52 - TTCGATTTCCTTTCTACCGA E|24|Q E|24|K SAH1 S-Adenosyl-l-Homocysteine hydrolase 449.0 0 1 0 0 0.07763961861636609 P39954 0.97645902633667 0.9644089937210084 0.2543879449367523 0.4342605471611023 49.37308192165 40.0 0.0 no 3301 chrV_237780 10181 high_effect YER044C 217 - TCTGATAACACAGGAAATAA R|79|T R|79|K ERG28 ERGosterol biosynthesis 148.0 0 0 0 0 -2.1131542866231983 P40030 0.932735025882721 0.955805003643036 0.0 0.0 34.12210663676814 30.0 0.0 yes 3302 chrV_237826 10185 high_effect YER044C 171 - CTCAAATGGGTTGTTTCAGT L|63|F silent|TTG>TTA|L|63 ERG28 ERGosterol biosynthesis 148.0 0 0 0 0 -3.699480621631293 P40030 0.9587849974632264 0.0 45.84261460015325 40.0 0.0 yes 3303 chrV_237883r 10186 high_effect YER044C 111 + TCTATCCAGACTTACGTTTC S|38|C S|38|F I|39|M silent|ATC>ATT|I|39 ERG28 ERGosterol biosynthesis 148.0 0 0 0 0 -0.013805192866450431 P40030 0.945252001285553 0.9294660091400146 0.9598389863967896 0.003896437119692564 0.0018629535334184766 0.03125018998980522 46.64287285682157 40.0 0.0 no 3304 chrV_237971r 10188 high_effect YER044C 23 + AACTACAACCAAGACCACCT T|9|S T|9|I T|10|R T|10|I ERG28 ERGosterol biosynthesis 148.0 0 0 0 0 -0.5621490950394032 P40030 0.9491789937019348 0.9472420215606691 0.9476869702339172 0.9472420215606691 1.0 0.02262590266764164 0.25476419925689703 0.2005099505186081 46.48369197876127 45.0 0.0 no 3305 chrV_293059r 10190 high_effect YER068W 12 - TGCAAATTTTCTTGAACGTG L|10|F silent|TTG>TTA|L|10 MOT2 Modulator Of Transcription 587.0 0 0 0 0 0.11073694070949301 P34909 39.25582388579744 35.0 1.0 no 3306 chrV_293148 10192 high_effect YER068W 98 + CCCTCTTTGTATTGAACCAA P|34|R P|34|L P|34|A P|34|S MOT2 Modulator Of Transcription 587.0 0 0 0 0 -0.1763581746221812 P34909 0.0 0.0 0.0 0.0 1.4670679569244385 1.8638617992401123 1.983192086219788 2.014044046401977 47.83945226963056 40.0 1.0 no 3307 chrV_293200r 10193 high_effect YER068W 153 - TGACAAATTTGATAACCACA C|57|S C|57|Y MOT2 Modulator Of Transcription 587.0 0 0 0 0 1.5020986986025675 P34909 0.0 0.0 1.075936794281006 4.277510166168213 36.99082623600145 30.0 1.0 no 3308 chrV_293272r 10198 high_effect YER068W 225 - TCATATTTACGACGACATGC D|82|H D|82|N MOT2 Modulator Of Transcription 587.0 0 0 0 0 0.9786942770765112 P34909 0.005207712762057781 0.015349982306361197 0.6099960207939148 0.35333600640296936 42.25747997800482 40.0 1.0 no 3309 chrV_293326r 10199 high_effect YER068W 279 - CTCTCCATTTTTAACTCCTC E|99|D silent|GAG>GAA|E|99 E|99|Q E|99|K MOT2 Modulator Of Transcription 587.0 0 1 0 0 0.4840595525297021 P34909 0.1571395844221115 0.061523295938968665 0.0635673776268959 48.97694231221783 40.0 1.0 no 3310 chrV_293541r 10204 high_effect YER068W 494 - TCTTATTTATCTTACCATAT K|171|N silent|AAG>AAA|K|171 MOT2 Modulator Of Transcription 587.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.6390148220655767 P34909 0.0 39.08076280810508 20.0 1.0 no 3311 chrV_293660r 10208 high_effect YER068W 613 - ACATCTTGCAGCATCGTCCT C|211|S C|211|Y R|210|T R|210|K MOT2 Modulator Of Transcription 587.0 0 0 0 0 -0.7371304243192599 P34909 0.0 0.0 0.03244863077998161 1.0 55.680275090027116 50.0 1.0 no 3312 chrV_293749 10212 high_effect YER068W 699 + TACTGTTCTTCTTATTTAAG Y|234|* silent|TAC>TAT|Y|234 MOT2 Modulator Of Transcription 587.0 0 0 0 0 -0.05961317467473301 P34909 37.35785391121812 25.0 1.0 no 3313 chrV_293789r 10214 high_effect YER068W 742 - TTCATGCAAAAACATACAGT E|254|Q E|254|K L|252|F silent|TTG>TTA|L|252 MOT2 Modulator Of Transcription 587.0 0 0 0 0 -0.44791891264210704 P34909 0.0 0.0 0.0 36.755603373165 30.0 1.0 no 3314 chrV_293986r 10218 high_effect YER068W 939 - AACTGAGCCCTCATCGCCGC Q|319|H silent|CAG>CAA|Q|319 MOT2 Modulator Of Transcription 587.0 0 0 0 0 -0.3308662791408048 P34909 0.08950410038232802 59.880342088872965 65.0 1.0 no 3315 chrV_294039 10220 high_effect YER068W 989 + ACCGGTATTAACACCTGCTC P|331|R P|331|L P|331|A P|331|S MOT2 Modulator Of Transcription 587.0 0 1 0 0 0.5128078891375651 P34909 0.0 0.0 0.0 0.0 51.298275428034856 50.0 1.0 no 3316 chrV_294079r 10225 high_effect YER068W 1032 - GCTGATTGAGTAACTCCCCA A|351|P A|351|T MOT2 Modulator Of Transcription 587.0 0 1 0 0 0.521038327177476 P34909 0.3428546786308289 0.8646484017372131 53.76644113528397 50.0 1.0 no 3317 chrV_302253 10229 no_effect YER071C 55 - TAACGTAACTAGTTTTCTTT silent|ACG>ACC|T|24 silent|ACG>ACA|T|24 TDA2 Topoisomerase I Damage Affected 126.0 0 0 0 0 0.9472899533686292 P40045 37.673916443120326 25.0 0.0 no 3318 chrV_302260 10230 no_effect YER071C 48 - ACTAGTTTTCTTTCGGGCAG V|23|L V|23|I TDA2 Topoisomerase I Damage Affected 126.0 0 0 0 0 -0.4757895628461155 P40045 0.9539830088615416 0.9574310183525084 0.22940847277641296 0.6679353713989258 49.97185867764267 45.0 0.0 no 3319 chrV_324762 10233 essential YER082C 1155 - ACACCTAGTAAATCTTCAAA G|391|A G|391|D V|392|L V|392|I UTP7 U Three Protein 554.0 0 0 0 0 -0.1340780867681896 P40055 0.9499930143356324 0.9446240067481996 0.9539830088615416 0.9574310183525084 0.0 0.0 0.2249457687139511 0.600817084312439 38.19441424301056 30.0 0.0 no 3320 chrV_324765r 10234 essential YER082C 1149 + GTACCATTTGAAGATTTACT P|385|A P|385|S P|385|R P|385|L UTP7 U Three Protein 554.0 0 0 0 0 0.2416354239796324 P40055 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.0 0.0 0.0 0.0 40.51111804238718 30.0 0.0 no 3321 chrV_324818 10237 essential YER082C 1099 - AAACAAATGTGACATGTAAG L|372|F silent|TTG>TTA|L|372 UTP7 U Three Protein 554.0 0 0 0 0 -0.17551310038424855 P40055 0.9587849974632264 0.5916792750358582 32.12001871338373 30.0 0.0 no 3322 chrV_324910 10243 essential YER082C 1007 - CCTTCCACAACGTAACGTGA K|342|N silent|AAG>AAA|K|342 W|341|C W|341|* UTP7 U Three Protein 554.0 0 0 0 0 0.5795977388501371 P40055 0.9355990290641784 0.8858469724655151 0.008024710230529308 0.002272054087370634 48.583436380747635 50.0 0.0 no 3323 chrV_325000r 10246 essential YER082C 914 + CTTCAAGCAACTACATTCTG F|306|L silent|TTC>TTT|F|306 UTP7 U Three Protein 554.0 0 0 0 0 -0.7069676827201511 P40055 0.9387490153312684 0.1074138656258583 42.13437923766458 40.0 0.0 no 3324 chrV_325222r 10255 essential YER082C 692 + AGCTGGGCCAACTATGGCAA A|232|G A|232|V UTP7 U Three Protein 554.0 0 0 0 0 0.8196595920591349 P40055 0.9484469890594482 0.9504740238189696 0.013667843304574491 0.09263741970062256 53.96576935565014 55.00000000000001 0.0 no 3325 chrV_325395r 10262 essential YER082C 519 + ACATTTATTTATGATCACGA T|174|R T|174|I UTP7 U Three Protein 554.0 0 0 0 0 0.020577780308370763 P40055 0.9476869702339172 0.9472420215606691 0.011092375963926315 0.11398917436599733 37.495288447075545 25.0 0.0 no 3326 chrV_325609r 10266 essential YER082C 305 + AGCTTTGGATTTATCTTTGA A|103|G A|103|V UTP7 U Three Protein 554.0 0 0 0 0 0.3823177768303184 P40055 0.9484469890594482 0.9504740238189696 0.41108763217926025 0.5453196763992311 43.302631846728445 30.0 0.0 no 3327 chrV_326371 10272 high_effect YER083C 641 - GTTCCACATTCTTCAATAGC E|220|Q E|220|K silent|GTG>GTC|V|219 silent|GTG>GTA|V|219 GET2 Guided Entry of Tail-anchored proteins 285.0 0 0 0 0 0.3245661117391111 P40056 0.97645902633667 0.9644089937210084 0.22667428851127625 0.023930393159389496 47.283226408024966 40.0 0.0 no 3328 chrV_326471r 10275 high_effect YER083C 538 + ATGCATTTACTCAATCAGCT A|181|G A|181|V GET2 Guided Entry of Tail-anchored proteins 285.0 0 0 0 0 -0.6394389045086427 P40056 0.9672009944915771 0.9664270281791688 0.4892100095748901 0.7545647621154785 45.019682580785904 35.0 0.0 no 3329 chrV_326558r 10281 high_effect YER083C 451 + CCTGGACCATTCTTGTGAAG silent|GCC>GCG|A|151 silent|GCC>GCT|A|151 T|153|S T|153|I GET2 Guided Entry of Tail-anchored proteins 285.0 0 0 0 0 -0.4664384501598068 P40056 0.9665899872779846 0.9646379947662354 0.7095052003860474 0.3782173991203308 49.5769982800619 50.0 0.0 no 3330 chrV_326587 10283 high_effect YER083C 425 - GTCTGTTCAGCAAGTAATCA R|148|T R|148|K GET2 Guided Entry of Tail-anchored proteins 285.0 0 0 0 0 -1.5178342458470568 P40056 0.955632984638214 0.9748079776763916 0.3220798671245575 1.0 46.040902457926684 40.0 0.0 no 3331 chrV_326613 10284 high_effect YER083C 399 - TCCAAAGCAGCTTGATTGAT L|139|F silent|TTG>TTA|L|139 D|140|H D|140|N GET2 Guided Entry of Tail-anchored proteins 285.0 0 0 0 0 0.548712937289183 P40056 0.9798439741134644 0.965224027633667 0.97645902633667 0.05100324004888535 0.08633662760257721 0.341474711894989 45.76814000716871 40.0 0.0 no 3332 chrV_326766r 10298 high_effect YER083C 243 + AAACAGCTCGCTGCCATGCA Q|83|E Q|83|* L|84|V L|84|F GET2 Guided Entry of Tail-anchored proteins 285.0 0 0 0 0 0.3934702545989984 P40056 0.9786580204963684 0.9703750014305116 0.9798439741134644 0.20894700288772586 0.02904304303228855 0.021201271563768387 54.24017499053417 55.00000000000001 0.0 no 3333 chrV_326782 10300 high_effect YER083C 230 - GCTGTTTCAATAGGTCCAAT Q|83|H silent|CAG>CAA|Q|83 GET2 Guided Entry of Tail-anchored proteins 285.0 0 0 0 0 -0.7946943544752377 P40056 0.9766640067100524 0.14797364175319672 47.60928423294689 40.0 0.0 no 3334 chrV_326814 10302 high_effect YER083C 198 - TTGCTATCTTCTTTGATATC S|72|T S|72|N GET2 Guided Entry of Tail-anchored proteins 285.0 0 0 0 0 0.3814794332417201 P40056 0.9669449925422668 0.9709960222244264 1.0 0.4638020098209381 42.23312040385019 30.0 0.0 no 3335 chrV_344804r 10327 essential YER093C 2786 + TTGCCGCGTCATTATCGGCA C|930|W silent|TGC>TGT|C|930 R|931|G R|931|C 0 0 0 0 -0.8703589743068794 P40061 0.9286419749259948 0.8994590044021606 0.8926740288734436 0.002296976977959275 0.009311692789196968 0.0012480850564315915 56.332247544031645 55.00000000000001 0.0 no 3336 chrV_344809r 10328 essential YER093C 2781 + TCACATTGCCGCGTCATTAT H|929|D H|929|Y S|928|* S|928|L 0 0 0 0 0.3209492736783397 P40061 0.9473130106925964 0.9489949941635132 0.9298099875450134 0.04714610055088997 0.13609164953231812 0.7000061869621277 51.34922160439999 45.0 0.0 no 3337 chrV_344881r 10330 essential YER093C 2709 + TTTCAATTTGAATCGAAACT Q|905|E Q|905|* 0 0 0 0 0.7039559248202496 P40061 0.9590039849281312 0.28308531641960144 34.41645548336845 25.0 0.0 no 3338 chrV_345080r 10334 essential YER093C 2510 + TACAAAAATTATACCGCAAC T|838|R T|838|I 0 0 0 0 0.5201496537047674 P40061 0.9476869702339172 0.9472420215606691 0.012820819392800331 0.01236502081155777 34.680939199515194 30.0 0.0 no 3339 chrV_345067 10335 essential YER093C 2526 - AACATTAAAGACGCCAGTTG M|848|I M|848|I 0 0 0 0 -0.4487078664201972 P40061 0.9553959965705872 0.9553959965705872 0.042171966284513474 0.042171966284513474 41.06138868185445 40.0 0.0 no 3340 chrV_345137r 10337 essential YER093C 2453 + CCAGTTTTTCAAAACACTAA Q|819|E Q|819|* 0 0 0 0 0.5798658535194088 P40061 0.9590039849281312 0.7786698937416077 38.16982300892215 30.0 0.0 no 3341 chrV_345398 10340 essential YER093C 2195 - ATCGGAAATCATCTACTTCG R|738|P R|738|Q 0 0 0 0 0.11888145135142072 P40061 0.9099509716033936 0.949662983417511 0.12800662219524386 0.3366008102893829 41.48098687501209 40.0 0.0 no 3342 chrV_346210 10346 essential YER093C 1383 - CGGCATTCTTTAACCATTTC C|467|S C|467|Y 0 0 0 0 0.2603334403614705 P40061 0.9421560168266296 0.9290120005607604 0.0 0.0 46.36816951479625 40.0 0.0 no 3343 chrV_346260 10348 essential YER093C 1333 - TTCTAATGCCATGTGCCTTA E|451|Q E|451|K 0 0 0 0 0.2341789530152829 P40061 0.956179976463318 0.9475290179252625 0.0 0.0 50.49688967680476 40.0 0.0 no 3344 chrV_346327r 10349 essential YER093C 1263 + TACAACAACGGTGTTACTCA Y|422|* silent|TAC>TAT|Y|422 N|423|K silent|AAC>AAT|N|423 0 0 0 0 -1.9880863004909868 P40061 0.9439849853515624 0.6205821633338928 42.62680353707572 40.0 0.0 no 3345 chrV_346531r 10351 essential YER093C 1059 + ATTCAAAATCTGCTTCTCAA Q|355|E Q|355|* 0 0 0 0 0.14712551390640266 P40061 0.9590039849281312 0.0457085445523262 39.45482349832838 30.0 0.0 no 3346 chrV_346706r 10356 essential YER093C 884 + CACATCCACAACAACTGAAG T|296|R T|296|I S|297|C S|297|F 0 0 0 0 -0.020627545181183617 P40061 0.9476869702339172 0.9472420215606691 0.945252001285553 0.9294660091400146 0.4735915064811706 0.1697724461555481 0.05098442360758781 0.04931709915399552 41.255521941960076 45.0 0.0 no 3347 chrV_346777r 10357 essential YER093C 813 + TCTAATAAAGTAAACTTAAC S|272|C S|272|F 0 0 0 0 -0.13114432968095324 P40061 0.945252001285553 0.9294660091400146 0.15450145304203033 0.5026483535766602 27.732419983177518 20.0 0.0 no 3348 chrV_346900r 10359 essential YER093C 690 + TATCTTACGACTCCCACTTC L|232|V L|232|F 0 0 0 0 0.35204572947821666 P40061 0.9512209892272948 0.9587849974632264 0.5015008449554443 0.7046871185302734 49.786061259568214 45.0 0.0 no 3349 chrV_346970 10360 essential YER093C 623 - ATTCTTCACTATCGTTATTT E|214|Q E|214|K E|213|Q E|213|K 0 0 0 0 0.824315523141187 P40061 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.24815917015075686 0.3419272899627685 0.4474984705448151 0.7774928212165833 41.36808921606871 25.0 0.0 no 3350 chrV_347014r 10362 essential YER093C 576 + AGCTCAATAAAGGCTGACGT S|193|R silent|AGC>AGT|S|193 S|194|* S|194|L 1 Series([], Name: modification, dtype: object) 0 0 0 0.7168410116509513 P40061 0.9417110085487366 0.9298099875450134 0.2189207524061203 0.3040153682231903 45.23370408193267 45.0 0.0 no 3351 chrV_347024r 10366 essential YER093C 566 + CACAACATCCAGCTCAATAA T|190|R T|190|I T|191|R T|191|I 0 1 0 0 0.02532009912528474 P40061 0.9476869702339172 0.9472420215606691 0.9476869702339172 0.9472420215606691 0.4521715641021729 0.24046316742897034 0.8039960861206055 0.4501828551292419 43.01298504135503 40.0 0.0 no 3352 chrV_347194r 10367 essential YER093C 396 + ACAATATCTGATATATACTC T|133|R T|133|I 0 0 0 0 -0.7325316268339964 P40061 0.01508032251149416 0.015968130901455883 34.40218088543168 25.0 0.0 no 3353 chrV_347329 10370 essential YER093C 264 - CTCGTTCGTCTTGCCATTAA silent|ACG>ACC|T|94 silent|ACG>ACA|T|94 R|93|P R|93|Q 0 0 0 0 0.10516162447581966 P40061 0.06771284341812134 0.3120030462741852 50.69324769026287 45.0 0.0 no 3354 chrV_347342r 10371 essential YER093C 248 + TTCACCGACCAGTCCCTTAA S|84|* S|84|L P|85|A P|85|S 1 Series([], Name: modification, dtype: object) 0 0 0 -1.3201628836484027 P40061 0.6956312656402588 0.0 0.0 54.670881978827374 50.0 0.0 no 3355 chrV_347367 10372 essential YER093C 226 - TGCACTATTTTCTAGCCTCT A|82|P A|82|T S|81|T S|81|N 0 1 0 0 -0.2435985041263853 P40061 0.4390121102333069 0.4669720530509949 0.7181646823883057 0.6006967425346375 51.497812136841105 40.0 0.0 no 3356 chrV_347370 10373 essential YER093C 223 - ACTATTTTCTAGCCTCTTGG S|81|T S|81|N 1 Series([], Name: modification, dtype: object) 0 0 0 0.6258990135272362 P40061 0.7181646823883057 0.6006967425346375 49.05750037973621 40.0 0.0 no 3357 chrV_348869 10379 essential YER094C 458 - GCTCTAGATTAGGTTCGTAC E|159|Q E|159|K E|159|D silent|GAG>GAA|E|159 PUP3 PUtative Proteasome subunit 205.0 0 0 0 0 0.19625694792601805 P25451 0.9603850245475768 0.9719409942626952 0.9952329993247986 0.1459711790084839 0.3346073031425476 0.9664390683174132 2.1690959930419917 2.3228800296783447 -1.2405200004577637 48.07704187815546 45.0 0.0 no 3358 chrV_348904r 10382 essential YER094C 420 + ACTGCATCCGACCAACTGTT T|141|S T|141|I A|142|G A|142|V PUP3 PUtative Proteasome subunit 205.0 0 0 0 0 0.3305974942529642 P25451 0.8282359838485718 0.6441180109977722 0.90317702293396 0.7039369940757751 0.0801314190030098 0.004521111957728864 0.4816811084747314 0.06242823973298073 0.2946600019931793 2.215320110321045 0.034359999001026154 3.546377897262573 -0.9128199815750122 6.059020042419434 52.35116712099961 50.0 0.0 no 3359 chrV_348927 10383 essential YER094C 400 - ACCGCTAACGATAAAATCCT G|140|R G|140|S G|140|A G|140|D PUP3 PUtative Proteasome subunit 205.0 0 0 0 0 -2.841018001515299 P25451 0.6182590126991272 0.6971849799156189 0.7007179856300354 0.6345800161361694 0.0 0.0 0.0 0.0 32.31732177734375 16.412321090698242 8.997761726379395 27.45708084106445 42.864149930450075 40.0 0.0 yes 3360 chrV_349021 10388 essential YER094C 306 - ACCACCGGCCCCACAAAGTA silent|GTG>GTC|V|108 silent|GTG>GTA|V|108 V|109|L V|109|I PUP3 PUtative Proteasome subunit 205.0 0 0 0 1 -6.432735603947233 P25451 0.9357730150222778 0.97325998544693 0.021740058436989784 1.0 0.6365600228309631 0.9247000217437744 57.961887489556325 60.0 0.0 yes 3361 chrV_349318r 10398 essential YER094C 6 + GATCCAAGTTCTATTAACGG P|4|A P|4|S P|4|R P|4|L PUP3 PUtative Proteasome subunit 205.0 0 1 0 0 -0.4115335017380678 P25451 0.9582589864730836 0.8148779869079591 0.7736489772796631 0.9193509817123412 0.2973184287548065 0.1265803724527359 0.07032611221075058 0.4520646929740906 1.7691600322723389 2.875341892242432 1.432420015335083 0.9100599884986876 42.48756533889782 40.0 0.0 no 3362 chrV_366863r 10402 essential YER104W 64 - ACCTGTACGCTGTAGTTCTG G|28|R G|28|S G|28|A G|28|D 0 0 0 0 -0.19873947380017856 P40063 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 52.38534544170824 50.0 1.0 no 3363 chrV_367118r 10417 essential YER104W 319 - TCGACGTCTAGTTAATCTCA R|113|P R|113|Q R|112|P R|112|H 0 0 0 0 0.5521898350670487 P40063 0.9099509716033936 0.949662983417511 0.9099509716033936 0.9570810198783876 0.18191209435462952 0.6820201277732849 0.0 0.0 44.97453283880873 40.0 1.0 no 3364 chrV_367151r 10419 essential YER104W 352 - TTCTAGGCCACCGCGTACTT E|124|Q E|124|K 0 0 0 0 0.5067941612283724 P40063 0.956179976463318 0.9475290179252625 0.05474913492798805 0.043243683874607086 57.353971578943394 55.00000000000001 1.0 no 3365 chrV_367245 10421 essential YER104W 443 + GAACGCTCTACCCTCTGACA N|149|K silent|AAC>AAT|N|149 A|150|G A|150|V 0 0 0 0 -1.1453885282803131 P40063 0.9439849853515624 0.9484469890594482 0.9504740238189696 0.3220300078392029 0.16601110994815824 0.4617508351802826 53.572415117676144 55.00000000000001 1.0 no 3366 chrV_410257r 10435 essential YER125W 71 - TCAGAACAGCAAACGGATCC silent|CTG>CTC|L|30 silent|CTG>CTA|L|30 V|29|L V|29|I RSP5 Reverses Spt- Phenotype 809.0 0 0 0 0 -1.3690181307940514 P39940 0.27958321571350103 0.1669563204050064 45.07836642697987 50.0 1.0 no 3367 chrV_410565r 10443 essential YER125W 379 - AACAATCAACCTACCGCTGA V|133|L V|133|I L|131|F silent|TTG>TTA|L|131 RSP5 Reverses Spt- Phenotype 809.0 0 0 0 0 0.19344654163046776 P39940 1.0 0.6309767365455627 0.013904338702559471 46.24366683331169 45.0 1.0 no 3368 chrV_410615 10444 essential YER125W 426 + CCGCATTCACAAGCTCCTTC H|144|D H|144|Y P|143|R P|143|L RSP5 Reverses Spt- Phenotype 809.0 0 1 0 0 -0.3957185609770116 P39940 0.6367762684822083 0.06671406328678131 0.4534411132335663 0.2673064172267914 55.156882811081225 55.00000000000001 1.0 no 3369 chrV_410717 10445 essential YER125W 528 + TCAACGTCTCATCCTTCCAG S|177|* S|177|L T|178|R T|178|M RSP5 Reverses Spt- Phenotype 809.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.3748078782319748 P39940 0.4254472553730011 0.5260737538337708 0.10963936150074004 52.4284010680243 50.0 1.0 no 3370 chrV_410776 10448 essential YER125W 587 + TACAACAGCTGCTACTAATA T|197|R T|197|I T|198|R T|198|I RSP5 Reverses Spt- Phenotype 809.0 0 1 0 0 0.1679244783956203 P39940 0.41576531529426575 0.2447747141122818 0.2945540249347687 0.11609307676553725 40.854084793305844 35.0 1.0 no 3371 chrV_410841r 10450 essential YER125W 655 - TTCAAACGAAGAGTATTGTC E|225|Q E|225|K silent|TCG>TCC|S|223 silent|TCG>TCA|S|223 RSP5 Reverses Spt- Phenotype 809.0 0 0 0 0 -1.9503632733259264 P39940 0.35817185044288635 0.329971581697464 37.34424504222415 35.0 1.0 no 3372 chrV_411077 10457 essential YER125W 888 + TCCTCTGTAACAGTTCAAGT silent|TCC>TCG|S|297 silent|TCC>TCT|S|297 S|297|C S|297|F RSP5 Reverses Spt- Phenotype 809.0 0 0 0 0 -0.18979031006776198 P39940 0.05582028254866599 0.1480586975812912 47.23928181324346 40.0 1.0 no 3373 chrV_411116r 10458 essential YER125W 930 - GCTGCTGCACCATTAACAGG A|317|P A|317|T A|316|P A|316|T RSP5 Reverses Spt- Phenotype 809.0 0 0 0 0 -1.009934963134397 P39940 0.27278879284858704 0.5380812883377075 0.2854253649711609 0.587266206741333 52.93821058048565 55.00000000000001 1.0 no 3374 chrV_411108r 10459 essential YER125W 922 - ACCATTAACAGGAGGTATAT G|314|R G|314|S G|314|A G|314|D RSP5 Reverses Spt- Phenotype 809.0 0 0 0 0 -2.2705367040161155 P39940 0.21419502794742584 0.4122735857963562 0.7617307305335999 0.4593049585819245 42.32911943484663 35.0 1.0 yes 3375 chrV_411258r 10470 essential YER125W 1072 - TCTCCTTGGATCCACCCAAG R|363|S silent|AGG>AGA|R|363 R|364|T R|364|K RSP5 Reverses Spt- Phenotype 809.0 0 0 0 0 -1.7402168794979085 P39940 0.007960462011396885 0.24368858337402344 1.0 56.20766754847802 55.00000000000001 1.0 no 3376 chrV_411281 10471 essential YER125W 1092 + CAACAGTATATACGTACTTA Q|366|E Q|366|* RSP5 Reverses Spt- Phenotype 809.0 0 0 0 0 -0.5509190022698525 P39940 0.42734894156456 37.47076693820981 30.0 1.0 no 3377 chrV_411616r 10480 essential YER125W 1430 - ATCTTTTCTTTAAATCTTCT R|483|T R|483|K RSP5 Reverses Spt- Phenotype 809.0 0 0 0 0 0.2947292235555262 P39940 0.0103752464056015 0.031763691455125816 0.8674200177192688 -0.0952399969100952 38.08202736198359 20.0 1.0 no 3378 chrV_411617r 10481 essential YER125W 1431 - AATCTTTTCTTTAAATCTTC R|483|T R|483|K RSP5 Reverses Spt- Phenotype 809.0 0 0 0 0 0.6986193666187792 P39940 0.0103752464056015 0.031763691455125816 0.8674200177192688 -0.0952399969100952 34.833429507381595 20.0 1.0 no 3379 chrV_411771r 10483 essential YER125W 1585 - ACTGTTAGGATTTATTTGAA S|535|T S|535|N RSP5 Reverses Spt- Phenotype 809.0 0 0 0 0 -0.10004273306979086 P39940 0.0 0.0 3.359639883041382 5.920360088348389 37.41978522026011 25.0 1.0 no 3380 chrV_413572 10487 essential YER126C 588 - TTCTTCTTAACTGCCAAAAT K|202|N silent|AAG>AAA|K|202 K|201|N silent|AAG>AAA|K|201 NSA2 Nop Seven Associated 261.0 0 0 0 0 -0.08747067444581172 P40078 0.004279380664229393 0.057312659919261925 40.31593583806523 30.0 0.0 no 3381 chrV_413585r 10488 essential YER126C 572 + AACTGTCTTCTTGCCAATTT T|192|S T|192|I silent|GTC>GTG|V|193 silent|GTC>GTT|V|193 NSA2 Nop Seven Associated 261.0 0 0 0 0 0.2956308142791513 P40078 0.07423845678567886 0.05620160698890686 46.420430057007025 35.0 0.0 no 3382 chrV_413701r 10490 essential YER126C 456 + AAACACACTTTTGTGGGTGA H|154|D H|154|Y H|154|Q silent|CAC>CAT|H|154 NSA2 Nop Seven Associated 261.0 0 0 0 0 -0.022532850460970755 P40078 0.2139205634593964 1.0 0.30089956521987915 43.79760251002017 40.0 0.0 no 3383 chrV_413675r 10491 essential YER126C 482 + CACTAGAAGACCAGTTAAAA T|162|S T|162|I NSA2 Nop Seven Associated 261.0 0 0 0 0 -0.5602124972225386 P40078 0.00923260860145092 0.02091530151665211 37.16698980576661 35.0 0.0 no 3384 chrV_413896 10493 essential YER126C 264 - TCTCTGTCCAATAGATATGT R|94|T R|94|K E|95|Q E|95|K NSA2 Nop Seven Associated 261.0 0 0 0 0 -2.223514543766418 P40078 0.004684537649154663 0.018778599798679352 0.3435293436050415 0.5640056133270264 44.642660107214105 35.0 0.0 yes 3385 chrV_413903r 10496 essential YER126C 254 + TGCTTTGCCGACATATCTAT A|86|G A|86|V NSA2 Nop Seven Associated 261.0 0 0 0 0 -0.35402539012915085 P40078 0.11158116906881332 0.08929013460874557 48.487912766034974 40.0 0.0 no 3386 chrV_414042 10503 essential YER126C 118 - CTTCCAACCAGTCAACTTCT W|45|C W|45|* W|45|S W|45|* NSA2 Nop Seven Associated 261.0 0 0 0 0 -2.1870938919568124 P40078 0.004702771548181772 0.00740951346233487 50.16999071898118 45.0 0.0 yes 3387 chrV_414154 10506 essential YER126C 6 - CGCTCGATATAATCGTTTTG E|8|D silent|GAG>GAA|E|8 E|8|Q E|8|K NSA2 Nop Seven Associated 261.0 0 0 0 0 -0.3964689223207562 P40078 42.40772118788891 40.0 0.0 no 3388 chrV_414525 10507 essential YER127W 44 + CACTGCGACATCAGAATCCT T|16|S T|16|I A|17|G A|17|V LCP5 Lethal with Conditional Pap1 357.0 0 1 0 0 -1.3091213637273422 P40079 0.6171556115150452 0.1583418846130371 0.25252223014831543 0.21476393938064572 49.09639688132762 50.0 1.0 no 3389 chrV_414496 10508 essential YER127W 15 + GCATTATTAAAAGATATCAA A|6|G A|6|V LCP5 Lethal with Conditional Pap1 357.0 0 1 0 0 -0.2790717988156819 P40079 0.2987963855266571 0.2315360456705093 31.46616297897515 20.0 1.0 no 3390 chrV_414542r 10510 essential YER127W 64 - AATCCCAGACAACCTCTCCA silent|GGG>GGC|G|27 silent|GGG>GGA|G|27 G|27|A G|27|E LCP5 Lethal with Conditional Pap1 357.0 0 0 0 0 -0.471128719855695 P40079 0.7308962941169739 1.0 53.621745371871775 50.0 1.0 no 3391 chrV_414656 10514 essential YER127W 175 + CGCTGCTATCCTTAAAAAAT L|60|V silent|CTG>TTG|L|60 L|61|V silent|CTA>TTA|L|61 LCP5 Lethal with Conditional Pap1 357.0 0 0 0 0 0.4637329654633604 P40079 0.0 0.02404107339680195 40.20600573010933 35.0 1.0 no 3392 chrV_414837r 10516 essential YER127W 359 - CTCTAGTCAGCTTGTCCAAT R|126|T R|126|K LCP5 Lethal with Conditional Pap1 357.0 0 0 0 0 -0.015595508254713038 P40079 0.029013440012931824 0.2647141218185425 51.5879772316045 45.0 1.0 no 3393 chrV_415246r 10529 essential YER127W 768 - CCAATAGATGCACTCCAGTC G|263|R G|263|S LCP5 Lethal with Conditional Pap1 357.0 0 0 0 0 -3.3491126022401962 P40079 0.0 0.0 50.521377096320975 50.0 1.0 yes 3394 chrV_415273 10530 essential YER127W 792 + GACATTGTGAACCATGGAAG D|265|E silent|GAC>GAT|D|265 LCP5 Lethal with Conditional Pap1 357.0 0 0 0 0 -0.3674212621785017 P40079 0.1866791695356369 42.50946240370308 45.0 1.0 no 3395 chrV_433230 10533 essential YER133W 210 + TTACTACGTCTATTTGAGTA L|72|V silent|CTA>TTA|L|72 R|73|G R|73|C GLC7 GLyCogen 312.0 0 0 0 0 0.09213805256337593 P32598 0.07819144427776338 0.045632507652044296 0.00032429117709398264 1.8203400373458865 40.69314966969984 30.0 1.0 no 3396 chrV_433398 10535 essential YER133W 378 + GCTTCCATTAATAGAATTTA A|127|G A|127|V S|128|C S|128|F GLC7 GLyCogen 312.0 0 1 0 0 0.2964958822177076 P32598 0.08306562155485152 0.056234918534755714 0.021427618339657784 0.05791619420051575 1.1513999700546265 2.15201997756958 1.2899800539016724 0.036419998854398734 -0.17076000571250916 -0.48157998919487 38.565500081907146 25.0 1.0 no 3397 chrV_433638 10542 essential YER133W 618 + GATCCAGATAAAGATATCGT P|208|A P|208|S P|208|R P|208|L GLC7 GLyCogen 312.0 0 0 0 0 -3.0952994922331074 P32598 0.0025390810333192353 0.0016528804553672671 0.0015950966626405714 0.0023892729077488184 39.88908634773236 35.0 1.0 yes 3398 chrV_439730 10548 essential YER136W 114 + GACAAGCAAGACCATTATGG D|39|E silent|GAC>GAT|D|39 Q|41|E Q|41|* GDI1 GDP Dissociation Inhibitor 451.0 0 0 0 0 0.3357035274546675 P39958 0.9532920122146606 0.9590039849281312 0.0 0.005792129784822464 0.2459399998188019 0.3406600058078766 43.22304801023614 45.0 1.0 no 3399 chrV_439741r 10549 essential YER136W 128 - AAGCAGCTTCGCCACCATAA A|49|P A|49|T A|48|P A|48|T GDI1 GDP Dissociation Inhibitor 451.0 0 0 0 0 0.3988024674118026 P39958 0.9573720097541808 0.9523990154266356 0.9573720097541808 0.9523990154266356 0.011249112896621227 0.1873013526201248 0.1795561909675598 0.2654296159744263 3.771480083465576 2.142659902572632 0.5156000256538391 0.2123800069093704 4.281077861785889 0.9153000116348268 1.1932599544525146 0.9071000218391418 52.45831915779644 50.0 1.0 no 3400 chrV_439871 10552 essential YER136W 255 + CCTAAATTCCTGATGGCCAA P|86|R P|86|L GDI1 GDP Dissociation Inhibitor 451.0 0 0 0 0 0.9398576470841842 P39958 0.9432820081710817 0.9430609941482544 0.0022643725387752056 0.0025207053404301405 5.498720169067383 0.9942799806594848 48.63742388981183 45.0 1.0 no 3401 chrV_440015 10559 essential YER136W 399 + GCCATTTCATCGCCATTGAT silent|GCC>GCG|A|134 silent|GCC>GCT|A|134 A|134|G A|134|V GDI1 GDP Dissociation Inhibitor 451.0 0 0 0 0 0.19756725101410466 P39958 0.9484469890594482 0.9504740238189696 0.012132099829614162 0.006044830661267042 1.0653400421142578 0.6802600026130676 1.0649399757385254 0.1889200061559677 52.991653563225725 45.0 1.0 no 3402 chrV_440181r 10561 essential YER136W 568 - TGCATGACCGATGAATTCTT A|196|P A|196|T GDI1 GDP Dissociation Inhibitor 451.0 0 0 0 0 -0.12431722823295055 P39958 0.9573720097541808 0.9523990154266356 0.008311210200190544 0.05078065767884255 2.008140087127685 2.363719940185547 5.101776123046875 1.6718000173568726 45.07930938516858 40.0 1.0 no 3403 chrV_440226 10563 essential YER136W 610 + ACTACTTACAACAACCTGCT D|204|E silent|GAC>GAT|D|204 Y|205|* silent|TAC>TAT|Y|205 GDI1 GDP Dissociation Inhibitor 451.0 0 0 0 0 -0.07909221374474304 P39958 0.9532920122146606 0.3604586124420166 -0.7911199927330017 44.94424557167201 40.0 1.0 no 3404 chrV_440249r 10565 essential YER136W 636 - AACAAAATCCTCTCAAACGA L|218|F silent|TTG>TTA|L|218 GDI1 GDP Dissociation Inhibitor 451.0 0 0 0 0 0.040449428837401435 P39958 0.9587849974632264 0.06259827315807343 0.6192600131034851 0.5594000220298767 37.628724082998815 35.0 1.0 no 3405 chrV_440344 10569 essential YER136W 728 + ACAAGGATTTGCTCGTTTGT Q|244|E Q|244|* GDI1 GDP Dissociation Inhibitor 451.0 0 0 0 0 0.5533603761750031 P39958 0.9590039849281312 0.43745356798172 0.3440800011157989 1.312559962272644 46.918642158298276 40.0 1.0 no 3406 chrV_440452 10571 essential YER136W 836 + GACTAAGCTGGGAACTTTCA T|280|S T|280|I GDI1 GDP Dissociation Inhibitor 451.0 0 0 0 0 0.4431003442609642 P39958 0.9491789937019348 0.9472420215606691 1.0 0.1883807182312012 1.2035000324249268 0.8333600163459778 45.71317114028751 45.0 1.0 no 3407 chrV_440620r 10576 essential YER136W 1007 - TATCGCTTTTCCTTCCCAGT D|342|H D|342|N S|341|T S|341|N GDI1 GDP Dissociation Inhibitor 451.0 0 0 0 0 -0.30776838527997297 P39958 0.9486550092697144 0.956179976463318 0.9512869715690612 0.9536849856376648 0.0 0.0 0.26529765129089355 1.0 11.456000328063965 1.6993999481201172 -0.8392000198364258 -0.5501400232315063 56.73770723479106 45.0 1.0 no 3408 chrV_463456r 10579 essential YER147C 1364 + ACTCGTAGAGCAATGCAACA silent|CTC>CTG|L|456 silent|CTC>CTT|L|456 L|456|V L|456|F SCC4 Sister Chromatid Cohesion 624.0 0 0 0 0 -0.6076021990998886 P40090 0.9950990080833436 1.0031700134277344 0.5050833225250244 0.6990311145782471 3.0157999992370605 1.0313999652862549 45.605465721862345 45.0 0.0 no 3409 chrV_463483 10580 essential YER147C 1340 - CCTGTTTGTCCCCCGAACAT Q|453|H silent|CAG>CAA|Q|453 SCC4 Sister Chromatid Cohesion 624.0 0 0 0 0 0.43186940573707705 P40090 1.0006899833679201 0.2372219711542129 0.2443999946117401 58.15095629987326 55.00000000000001 0.0 no 3410 chrV_463586 10588 essential YER147C 1237 - AAGCCGCGTGTACTCTTCTA silent|CGG>CGC|R|418 silent|CGG>CGA|R|418 R|418|P R|418|Q SCC4 Sister Chromatid Cohesion 624.0 0 0 0 0 0.04379648393397051 P40090 0.960108995437622 0.9936749935150146 0.2681038677692413 0.5764511823654175 3.2026000022888184 0.19280000030994413 53.326191100709146 50.0 0.0 no 3411 chrV_463616 10590 essential YER147C 1207 - GCCTTCAAACTGAACCTTCA G|409|R G|409|S G|409|A G|409|D SCC4 Sister Chromatid Cohesion 624.0 0 0 0 0 0.6441739983897766 P40090 0.9727219939231871 0.9916149973869324 0.9903749823570251 0.9780880212783812 0.6504159569740295 1.0 0.9654223918914796 0.6748611927032471 1.817199945449829 2.5460000038146973 2.7609999179840092 2.4577999114990234 48.420926122332496 45.0 0.0 no 3412 chrV_463671r 10596 essential YER147C 1149 + ACGACCGAGTCACCTAAGTT T|384|R T|384|M T|385|S T|385|I SCC4 Sister Chromatid Cohesion 624.0 0 1 0 0 -0.5465100424733197 P40090 0.9773380160331726 0.9916599988937378 0.9913139939308168 0.9893620014190674 0.6803978085517883 0.26550015807151794 0.465717762708664 0.11944530159235 50.251463201675556 50.0 0.0 no 3413 chrV_463790 10599 essential YER147C 1033 - ATTCATCGAAACACCGCCAG M|350|I M|350|I silent|TCG>TCC|S|349 silent|TCG>TCA|S|349 SCC4 Sister Chromatid Cohesion 624.0 0 0 0 0 0.8818726760940363 P40090 0.999705970287323 0.999705970287323 0.2597024142742157 0.2597024142742157 2.5546000003814697 2.5546000003814697 47.867173060521225 50.0 0.0 no 3414 chrV_463832 10600 essential YER147C 991 - CTGCGTTGTAGAATAGACTT silent|ACG>ACC|T|336 silent|ACG>ACA|T|336 SCC4 Sister Chromatid Cohesion 624.0 0 0 0 0 0.2551580261410298 P40090 43.65529654600697 40.0 0.0 no 3415 chrV_463971 10605 essential YER147C 852 - TCTACTTTCAGCGCTATCCT E|291|Q E|291|K V|290|L V|290|I SCC4 Sister Chromatid Cohesion 624.0 0 0 0 0 0.02387947814415771 P40090 1.0004899501800537 0.9891330003738404 0.9940739870071412 1.0010499954223633 0.5342613458633423 0.7514071464538574 0.4698646068572998 1.0 -0.24480000138282776 -0.5317999720573425 0.239999994635582 -0.3853999972343445 53.34436838089749 45.0 0.0 no 3416 chrV_464014r 10606 essential YER147C 806 + TCTAGTCACTAATGAAGGTA L|270|V silent|CTA>TTA|L|270 silent|GTC>GTG|V|271 silent|GTC>GTT|V|271 SCC4 Sister Chromatid Cohesion 624.0 0 0 0 0 0.9891937764092388 P40090 0.9950990080833436 0.1261032521724701 2.1568000316619877 40.48802342808568 35.0 0.0 no 3417 chrV_464130 10608 essential YER147C 693 - AACTTCCATGCATATAGCTC K|237|N silent|AAG>AAA|K|237 W|236|C W|236|* SCC4 Sister Chromatid Cohesion 624.0 0 0 0 0 -1.2681647309951614 P40090 0.9806249737739564 0.9440850019454956 0.14907537400722504 0.0 4.824399948120117 5.062399864196777 46.759322615974845 40.0 0.0 no 3418 chrV_464457 10622 essential YER147C 366 - AACTTACTGTCTCTCATAAG K|128|N silent|AAG>AAA|K|128 S|127|T S|127|N SCC4 Sister Chromatid Cohesion 624.0 0 0 0 0 0.8949050739175277 P40090 0.9806249737739564 0.9916689991950988 0.9957190155982972 0.029313115403056145 0.9136036038398744 0.3680875599384308 0.631600022315979 0.5009999871253967 0.09380000084638596 40.18851044238409 35.0 0.0 no 3419 chrV_465408r 10631 essential YER148W 108 - TCACTCTGGAAAGTAGTTGC S|42|T S|42|N E|43|Q E|43|K SPT15 SuPpressor of Ty insertions 240.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.26762915327008 P13393 1.0115000009536743 1.0149300098419192 1.0151400566101074 1.0056699514389038 0.6369054317474365 0.7151461839675903 0.59331876039505 0.89308100938797 45.735573157202786 45.0 1.0 no 3420 chrV_465494 10634 essential YER148W 191 + TCCAACACTACAAAACATTG P|65|R P|65|L P|65|A P|65|S SPT15 SuPpressor of Ty insertions 240.0 0 0 0 0 -0.9799711995967472 P13393 0.531948983669281 0.6818580031394958 0.7469509840011597 0.7723379731178284 0.0022334442473948 0.06886184215545654 0.01976757310330868 0.003983933478593825 12.06594181060791 5.652966022491455 3.036370038986206 4.924466133117676 37.39775822254825 35.0 1.0 no 3421 chrV_465495r 10635 essential YER148W 195 - GCCACAATGTTTTGTAGTGT silent|GTG>GTC|V|71 silent|GTG>GTA|V|71 A|72|P A|72|T SPT15 SuPpressor of Ty insertions 240.0 0 0 0 0 0.1816413846507972 P13393 0.5578609704971313 0.7443869709968567 0.01728932373225689 0.012179510667920113 2.1275439262390137 -0.2121479958295822 2.0942850112915044 0.7126700282096863 48.83534956423489 40.0 1.0 no 3422 chrV_465637 10638 essential YER148W 334 + CAGCTTTAATTTTTGCCTCA A|113|G A|113|V SPT15 SuPpressor of Ty insertions 240.0 0 0 0 0 0.9006964705151246 P13393 0.6393169760704039 0.75484699010849 0.04598219320178032 0.06542455404996872 1.831820011138916 -1.635740041732788 2.0654768943786617 3.05420184135437 47.17964798060524 35.0 1.0 no 3423 chrV_465673r 10640 essential YER148W 373 - GTCATCCTCACTTTTTGCAC D|131|H D|131|N D|130|H D|130|N SPT15 SuPpressor of Ty insertions 240.0 0 1 0 0 -1.783369104049256 P13393 0.8820210099220276 0.893684983253479 0.9408209919929504 0.9669489860534668 0.10265210270881653 0.3645518720149994 0.20771831274032596 0.11273140460252762 -0.6477640271186829 -0.5499200224876404 0.6606760025024414 0.7579200267791748 1.0712000131607056 0.30300000309944153 52.19359352172153 45.0 1.0 no 3424 chrV_477976 10641 high_effect YER155C 4853 - ACCTTGAAATGAACCAACCA R|1624|T R|1624|K R|1624|S silent|AGG>AGA|R|1624 BEM2 Bud EMergence 2167.0 0 0 0 0 -0.1948967134144497 P39960 0.932735025882721 0.955805003643036 0.9087679982185364 0.0 0.0 0.0 43.32246819075283 40.0 0.0 no 3425 chrV_478090 10642 high_effect YER155C 4739 - TACTAATCGATCTTAGATTT S|1586|T S|1586|N BEM2 Bud EMergence 2167.0 0 0 0 0 0.6632762691442137 P39960 0.9512869715690612 0.9536849856376648 0.7232037782669067 0.43580618500709534 36.64039090130535 25.0 0.0 no 3426 chrV_478091 10643 high_effect YER155C 4738 - ACTAATCGATCTTAGATTTT S|1586|T S|1586|N silent|TCG>TCC|S|1584 silent|TCG>TCA|S|1584 BEM2 Bud EMergence 2167.0 0 0 0 0 -0.3171186424784571 P39960 0.9512869715690612 0.9536849856376648 0.7232037782669067 0.43580618500709534 37.42803774787376 25.0 0.0 no 3427 chrV_478279 10647 high_effect YER155C 4550 - CCAAACTTCCGTTTTTCCAG L|1523|F silent|TTG>TTA|L|1523 S|1522|T S|1522|N BEM2 Bud EMergence 2167.0 0 0 0 0 0.5656838736261612 P39960 0.9587849974632264 0.9512869715690612 0.9536849856376648 0.053943797945976264 0.2137531340122223 0.1300378441810608 49.33353774034129 45.0 0.0 no 3428 chrV_478343r 10649 high_effect YER155C 4483 + TCAACAAAAGCAGTAGTGAA silent|GTC>GTG|V|1495 silent|GTC>GTT|V|1495 N|1496|K silent|AAC>AAT|N|1496 BEM2 Bud EMergence 2167.0 0 0 0 0 -0.9495957702772188 P39960 0.9439849853515624 0.8610823154449463 36.934939402406776 35.0 0.0 no 3429 chrV_478560 10652 high_effect YER155C 4269 - TTGCTTGACTTAAAATGTAG S|1429|T S|1429|N BEM2 Bud EMergence 2167.0 0 0 0 0 1.2432431442031446 P39960 0.9512869715690612 0.9536849856376648 0.3837950229644776 0.3120648562908173 36.12167548385651 30.0 0.0 no 3430 chrV_478709 10653 high_effect YER155C 4120 - TTCTAGTATATCTTCGTAAT E|1380|Q E|1380|K BEM2 Bud EMergence 2167.0 0 0 0 0 0.03919035045085645 P39960 0.956179976463318 0.9475290179252625 0.5305926203727722 0.9586625099182128 38.65054683388354 25.0 0.0 no 3431 chrV_478869r 10656 high_effect YER155C 3957 + AAGCAACTATACAGACCTAT Q|1321|E Q|1321|* L|1322|V silent|CTA>TTA|L|1322 BEM2 Bud EMergence 2167.0 0 1 0 0 -1.3014287728781202 P39960 0.9590039849281312 0.9512209892272948 0.02133976481854916 0.028150243684649467 41.10067513138404 35.0 0.0 no 3432 chrV_478911r 10657 high_effect YER155C 3915 + ACGTTAACTGATCTATTTCA T|1306|R T|1306|M BEM2 Bud EMergence 2167.0 0 0 0 0 0.2511577530290788 P39960 0.9476869702339172 0.9502379894256592 0.7674716711044312 0.0662693977355957 40.1661312796561 30.0 0.0 no 3433 chrV_479152r 10660 high_effect YER155C 3674 + AAACATAAACCTTATTTATA N|1226|K silent|AAC>AAT|N|1226 BEM2 Bud EMergence 2167.0 0 0 0 0 0.7281404609393535 P39960 0.9439849853515624 0.9234490394592284 31.0333638541469 15.0 0.0 no 3434 chrV_479198r 10661 high_effect YER155C 3628 + ACGACCAAAATTTTCCTGTT Y|1210|* silent|TAC>TAT|Y|1210 D|1211|E silent|GAC>GAT|D|1211 BEM2 Bud EMergence 2167.0 0 0 0 0 -0.3973187506388711 P39960 0.9532920122146606 0.9534940719604492 43.46959556943864 35.0 0.0 no 3435 chrV_479273 10662 high_effect YER155C 3556 - ATCACTGCGATCTAAAATCT D|1192|H D|1192|N S|1191|T S|1191|N BEM2 Bud EMergence 2167.0 0 0 0 0 0.6370958065330247 P39960 0.9486550092697144 0.956179976463318 0.9512869715690612 0.9536849856376648 0.09307332336902617 0.5713168978691101 0.3340713381767273 1.0 40.58731866833796 35.0 0.0 no 3436 chrV_479353r 10663 high_effect YER155C 3473 + AAGCTTTACTACTACAACTA S|1159|R silent|AGC>AGT|S|1159 BEM2 Bud EMergence 2167.0 0 0 0 0 0.5314525597657648 P39960 0.9417110085487366 0.0 38.668885484735206 30.0 0.0 no 3437 chrV_479416r 10664 high_effect YER155C 3410 + TGCATTCGTTAAACTAACTA A|1138|G A|1138|V F|1139|L silent|TTC>TTT|F|1139 BEM2 Bud EMergence 2167.0 0 0 0 0 0.005363360668283662 P39960 0.9484469890594482 0.9504740238189696 0.9387490153312684 0.0 0.0 0.3068311810493469 38.17155520268261 30.0 0.0 no 3438 chrV_479707r 10667 high_effect YER155C 3119 + CCAAAAGATGAGAGATTCCT Q|1041|E Q|1041|* BEM2 Bud EMergence 2167.0 0 1 0 0 -0.3491627772249767 P39960 0.9590039849281312 0.9686387181282043 41.92332794175286 40.0 0.0 no 3439 chrV_479937 10670 high_effect YER155C 2892 - GACGACATCTCTTTGATCAC silent|TCG>TCC|S|970 silent|TCG>TCA|S|970 M|969|I M|969|I BEM2 Bud EMergence 2167.0 0 0 0 1 -0.20149672931339896 P39960 0.9553959965705872 0.9553959965705872 0.7707458138465881 0.7707458138465881 45.15523161608144 45.0 0.0 no 3440 chrV_480034r 10671 high_effect YER155C 2792 + AGCTTCAAACAGTCACACTA A|932|G A|932|V S|933|* S|933|L BEM2 Bud EMergence 2167.0 0 0 0 0 0.28093730153889457 P39960 0.9484469890594482 0.9504740238189696 0.9298099875450134 0.345447450876236 0.3781000077724457 0.3100920617580414 44.3835297799904 40.0 0.0 no 3441 chrV_480033r 10672 high_effect YER155C 2793 + GCTTCAAACAGTCACACTAT A|932|G A|932|V S|933|* S|933|L BEM2 Bud EMergence 2167.0 0 0 0 0 -2.720738604285612 P39960 0.9484469890594482 0.9504740238189696 0.9298099875450134 0.345447450876236 0.3781000077724457 0.3100920617580414 44.31682243557458 40.0 0.0 yes 3442 chrV_480141r 10676 high_effect YER155C 2685 + TTTCCTAAGAATACATTAGT P|897|A P|897|S P|897|R P|897|L BEM2 Bud EMergence 2167.0 0 1 0 0 0.28650261740398786 P39960 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.2721375524997711 0.4397235214710236 0.010999318212270737 0.013875006698071957 37.58383615490021 25.0 0.0 no 3443 chrV_480230r 10677 high_effect YER155C 2596 + ATTCTACTATTGGTTCTCAA S|867|C S|867|F T|868|S T|868|I BEM2 Bud EMergence 2167.0 0 0 0 0 0.8930658633878521 P39960 0.945252001285553 0.9294660091400146 0.9491789937019348 0.9472420215606691 0.015820395201444626 0.16273629665374756 0.9432243704795836 0.17959001660346985 42.32932450268135 30.0 0.0 no 3444 chrV_480303 10680 high_effect YER155C 2526 - ATTCCTTCAATGTTCAACGG G|848|A G|848|E G|848|R G|848|R BEM2 Bud EMergence 2167.0 0 0 0 0 0.039284485742949515 P39960 0.9499930143356324 0.9438679814338684 0.941340982913971 0.941340982913971 0.7620777487754822 1.0 0.4702922701835632 0.4702922701835632 44.78044765372886 40.0 0.0 no 3445 chrV_480492 10681 high_effect YER155C 2337 - TACTTGAATTTCGTATCAGA K|785|N silent|AAG>AAA|K|785 BEM2 Bud EMergence 2167.0 0 0 0 0 0.8496563177935681 P39960 0.9355990290641784 0.011459984816610813 39.150594855044396 30.0 0.0 no 3446 chrV_480543r 10682 high_effect YER155C 2283 + GCTAACGTGATTTCTTATTT A|762|G A|762|V N|763|K silent|AAC>AAT|N|763 BEM2 Bud EMergence 2167.0 0 0 0 0 0.6795180374540031 P39960 0.9484469890594482 0.9504740238189696 0.9439849853515624 0.310818612575531 0.19165554642677307 0.013631932437419891 41.570918749569046 30.0 0.0 no 3447 chrV_480638 10684 high_effect YER155C 2191 - TCGCCTCTCTAACTGAATAA R|736|S silent|AGG>AGA|R|736 R|737|P R|737|Q BEM2 Bud EMergence 2167.0 0 0 0 0 0.008880137177093156 P39960 0.9087679982185364 0.9099509716033936 0.949662983417511 0.0 0.0 0.0 44.18158424468084 40.0 0.0 no 3448 chrV_480641r 10685 high_effect YER155C 2185 + CTACCATTATTCAGTTAGAG T|730|S T|730|I silent|ACC>ACG|T|730 silent|ACC>ACT|T|730 BEM2 Bud EMergence 2167.0 0 0 0 0 0.5676515725990673 P39960 0.9491789937019348 0.9472420215606691 0.0 0.0 41.85623849387071 35.0 0.0 no 3449 chrV_481293r 10692 high_effect YER155C 1533 + ACAATCCTTGATGTATTTCC T|512|R T|512|I I|513|M silent|ATC>ATT|I|513 BEM2 Bud EMergence 2167.0 0 0 0 0 -0.0616026881361853 P39960 0.9476869702339172 0.9472420215606691 0.9598389863967896 0.006257487460970879 0.034008469432592385 0.017663506790995598 44.87730221464528 35.0 0.0 no 3450 chrV_481444r 10696 high_effect YER155C 1382 + TCATTTCATTAAGTTTCTAA H|462|D H|462|Y F|463|L silent|TTC>TTT|F|463 BEM2 Bud EMergence 2167.0 0 0 0 0 -0.23955341351763945 P39960 0.9473130106925964 0.9489949941635132 0.9387490153312684 0.8876652121543884 0.07253522425889969 0.296082079410553 36.04550714258511 20.0 0.0 no 3451 chrV_481557r 10699 high_effect YER155C 1269 + CACACAGTCTTATTTTACCC H|424|Q silent|CAC>CAT|H|424 T|425|R T|425|I BEM2 Bud EMergence 2167.0 0 0 0 0 -0.7675478896924258 P39960 0.9588389992713928 0.9476869702339172 0.9472420215606691 0.0 0.2552759051322937 0.13438111543655396 47.55660441688696 40.0 0.0 no 3452 chrV_481870 10706 high_effect YER155C 959 - TCAATTGAGCCCTATAAAGA L|326|F silent|TTG>TTA|L|326 BEM2 Bud EMergence 2167.0 0 0 0 0 0.023233696554525986 P39960 0.9587849974632264 0.0 41.97875430181659 35.0 0.0 no 3453 chrV_481946 10708 high_effect YER155C 883 - CACATCATTGCCACTGTTAG V|301|L V|301|M D|300|H D|300|N BEM2 Bud EMergence 2167.0 0 1 0 0 0.0888068713783622 P39960 0.9539830088615416 0.9587630033493042 0.9486550092697144 0.956179976463318 0.6404799222946167 0.20716777443885806 0.08594638109207152 0.4727678596973419 48.24717623991143 45.0 0.0 no 3454 chrV_482038 10711 high_effect YER155C 791 - TTCTAGAATACGCATCATTA R|270|T R|270|K BEM2 Bud EMergence 2167.0 0 0 0 0 0.5188937100293346 P39960 0.932735025882721 0.955805003643036 0.6861500144004822 1.0 39.6607685865344 30.0 0.0 no 3455 chrV_482152r 10713 high_effect YER155C 674 + AACTGTTTTTAAGACTGGAT T|226|S T|226|I BEM2 Bud EMergence 2167.0 0 0 0 0 -0.2408713222901239 P39960 0.9491789937019348 0.9472420215606691 0.13690702617168427 0.1380586177110672 38.626802317840884 30.0 0.0 no 3456 chrV_482384 10720 high_effect YER155C 445 - GGCACTCTTCTTGTACGCAA A|155|P A|155|T S|154|T S|154|N BEM2 Bud EMergence 2167.0 0 1 0 0 -0.647414252727347 P39960 0.9573720097541808 0.9523990154266356 0.9512869715690612 0.9536849856376648 0.3373775780200958 0.6857309937477112 0.44555121660232544 0.2644495368003845 52.12433066728874 50.0 0.0 no 3457 chrV_482385 10721 high_effect YER155C 444 - GCACTCTTCTTGTACGCAAT S|154|T S|154|N A|155|P A|155|T BEM2 Bud EMergence 2167.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.15598230918413047 P39960 0.9512869715690612 0.9536849856376648 0.9573720097541808 0.9523990154266356 0.44555121660232544 0.2644495368003845 0.3373775780200958 0.6857309937477112 49.695684379870215 45.0 0.0 no 3458 chrV_482540 10728 high_effect YER155C 289 - CATCCCCAAGTTCACCTGAC silent|GGG>GGC|G|102 silent|GGG>GGA|G|102 G|102|A G|102|E BEM2 Bud EMergence 2167.0 0 0 0 1 0.5626628542824644 P39960 0.9499930143356324 0.9438679814338684 0.9109404683113098 1.0 55.281255679645604 55.00000000000001 0.0 no 3459 chrV_482635 10733 high_effect YER155C 194 - CTCTGTGGTGACTGTGTCCC R|71|T R|71|K BEM2 Bud EMergence 2167.0 0 0 0 0 -0.4213542528047665 P39960 0.932735025882721 0.955805003643036 0.5066785216331482 1.0 59.61228907515539 60.0 0.0 no 3460 chrV_484858r 10740 essential YER157W 73 - ATCGTCCAGTAAACCCACTA D|31|H D|31|N D|30|H D|30|N COG3 Conserved Oligomeric Golgi complex 801.0 0 0 0 0 -0.4415326884772833 P40094 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.0 0.0 0.012775098904967308 0.026966046541929245 49.90425970226386 45.0 1.0 no 3461 chrV_485301r 10745 essential YER157W 516 - GAGCTCTTCTTAACAATAGC S|178|T S|178|N K|177|N silent|AAG>AAA|K|177 COG3 Conserved Oligomeric Golgi complex 801.0 0 0 0 0 0.9715494019997922 P40094 0.9512869715690612 0.9536849856376648 0.9355990290641784 0.03369250148534775 0.4196487963199616 0.02117768302559853 43.374746798977576 40.0 1.0 no 3462 chrV_485638r 10748 essential YER157W 853 - TTCATCGTGATACTTGTTGT E|291|Q E|291|K D|290|H D|290|N COG3 Conserved Oligomeric Golgi complex 801.0 0 0 0 0 -0.7712523276309706 P40094 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.0 0.0 0.07598020881414412 0.4972399473190308 45.009940669947746 35.0 1.0 no 3463 chrV_485705 10750 essential YER157W 917 + ACGTTTAAGACTGCTAACTC R|307|G R|307|C COG3 Conserved Oligomeric Golgi complex 801.0 0 0 0 0 -0.8430635930692396 P40094 0.8994590044021606 0.8926740288734436 0.0 0.0 42.09812530447522 40.0 1.0 no 3464 chrV_485872 10751 essential YER157W 1084 + GTCGTTTCAAGATTAATCAG R|363|G R|363|C COG3 Conserved Oligomeric Golgi complex 801.0 0 0 0 0 -0.3043271296040451 P40094 0.8994590044021606 0.8926740288734436 0.045530632138252265 0.005358153022825718 39.521464590670405 35.0 1.0 no 3465 chrV_485913r 10752 essential YER157W 1128 - ACTCTAATGGAGTCATAAAG R|382|T R|382|K V|383|L V|383|I COG3 Conserved Oligomeric Golgi complex 801.0 0 0 0 0 -1.5471056527356302 P40094 0.932735025882721 0.955805003643036 0.9539830088615416 0.9574310183525084 0.2554897665977478 0.1827435940504074 0.3409749567508697 0.33001604676246643 37.212193456404975 35.0 1.0 no 3466 chrV_485926r 10755 essential YER157W 1141 - TTTCAAAACCCTGACTCTAA L|386|F silent|TTG>TTA|L|386 COG3 Conserved Oligomeric Golgi complex 801.0 0 0 0 0 1.2126812660597022 P40094 0.9587849974632264 0.05590928345918656 41.87885676134249 35.0 1.0 no 3467 chrV_485994r 10756 essential YER157W 1209 - CCTTCTTCAAATTCATAATA G|410|R G|410|S E|409|Q E|409|K COG3 Conserved Oligomeric Golgi complex 801.0 0 0 0 0 0.9536536400934016 P40094 0.941340982913971 0.951104998588562 0.956179976463318 0.9475290179252625 0.11657193303108215 0.3713241815567017 0.0 0.0 37.67336770212341 25.0 1.0 no 3468 chrV_491770 10774 essential YER159C 169 - CTGCATTATTTTCTTTACCT M|62|I M|62|I BUR6 Bypass UAS Requirement 142.0 0 1 0 0 -0.006850350788878773 P40096 0.9553959965705872 0.9553959965705872 0.07271258533000946 0.07271258533000946 0.9734740257263184 0.9734740257263184 45.38644051428661 30.0 0.0 no 3469 chrV_491787r 10775 essential YER159C 149 + GACACACTTCCCTCCGGCCA T|51|R T|51|I H|52|D H|52|Y BUR6 Bypass UAS Requirement 142.0 0 0 0 0 -0.14946524362327915 P40096 0.9476869702339172 0.9472420215606691 0.9473130106925964 0.9489949941635132 0.0 0.0 0.01158878393471241 0.029268348589539524 62.933758588658236 65.0 0.0 no 3470 chrV_491900 10779 essential YER159C 39 - ACCTCATGTTCAGGTTTTAT E|19|D silent|GAG>GAA|E|19 V|20|L V|20|I BUR6 Bypass UAS Requirement 142.0 0 0 0 0 -0.20939400758626267 P40096 0.94931298494339 0.9539830088615416 0.9574310183525084 0.6620993614196777 0.657550036907196 0.3994079232215881 48.154853679845765 35.0 0.0 no 3471 chrV_510566r 10782 essential YER165W 196 - ATCACGACAGACACGAATGG D|72|H D|72|N R|71|P R|71|H PAB1 Poly(A) Binding protein 577.0 0 1 0 0 0.07851892642461482 P04147 0.741769015789032 0.8676210045814514 0.6909700036048889 0.7171059846878052 0.0 0.0 0.0 0.0 43.1049345597379 50.0 1.0 no 3472 chrV_510589 10784 essential YER165W 216 + GCCATCACTAAGACCTCTTT silent|GCC>GCG|A|73 silent|GCC>GCT|A|73 A|73|G A|73|V PAB1 Poly(A) Binding protein 577.0 0 0 0 1 0.010638681487615377 P04147 0.962565004825592 0.9639059901237488 0.1922321766614914 0.9461766481399536 0.2536860108375549 0.3221920132637024 51.21380594889683 45.0 1.0 no 3473 chrV_510636r 10787 essential YER165W 266 - TTGCTTTTCTGCCGGCTTCA A|95|P A|95|T PAB1 Poly(A) Binding protein 577.0 0 1 0 0 0.35865212241891997 P04147 0.6275449991226196 0.665058970451355 0.0041354247368872174 0.004025871865451336 11.588793754577635 5.851163864135742 57.85668267489507 50.0 1.0 no 3474 chrV_510724r 10791 essential YER165W 354 - GAACCCTTCTTTCTCAATGA G|124|A G|124|D G|124|R G|124|S PAB1 Poly(A) Binding protein 577.0 0 1 0 0 -0.6343150321101747 P04147 0.7789750099182129 0.6293690204620361 0.58610600233078 0.8022879958152771 0.005138514097779989 0.009868265129625796 0.001909723505377769 0.006674567237496376 47.17014081785908 40.0 1.0 no 3475 chrV_510849 10794 essential YER165W 476 + CGACGAAAACGGAAAATCCA D|160|E silent|GAC>GAT|D|160 PAB1 Poly(A) Binding protein 577.0 0 1 0 0 0.40774906015605095 P04147 0.9282709956169128 0.004149037413299085 38.55397160882069 45.0 1.0 no 3476 chrV_510996 10797 essential YER165W 623 + CTCTCAATTGGAAGAGACTA S|209|C S|209|F Q|210|E Q|210|* PAB1 Poly(A) Binding protein 577.0 0 0 0 0 0.15953910979325805 P04147 0.8462349772453308 0.8378400206565857 1.0370299816131592 0.027763396501541138 0.02786913514137268 1.0 41.205983988297476 40.0 1.0 no 3477 chrV_511254r 10800 essential YER165W 884 - GCATACGTTCATTCTTCTTT M|301|I M|301|I R|300|P R|300|H PAB1 Poly(A) Binding protein 577.0 0 1 0 0 0.519565130873099 P04147 1.0210900306701658 1.0210900306701658 0.861657977104187 0.7976099848747253 0.07211152464151382 0.07211152464151382 0.0 0.0 47.16102558773383 35.0 1.0 no 3478 chrV_511482 10805 essential YER165W 1109 + AACTCCAGAGGAAGCTACTA T|371|S T|371|I P|372|A P|372|S PAB1 Poly(A) Binding protein 577.0 0 0 0 0 0.5341085541091386 P04147 1.020859956741333 0.9603859782218932 0.9606490135192872 0.9328060150146484 1.0 0.01007333770394325 0.1500002294778824 0.04972108453512192 46.2075935485579 45.0 1.0 no 3479 chrV_511521r 10806 essential YER165W 1151 - GCTTACCAGCAACAATTTGT K|390|N silent|AAG>AAA|K|390 G|389|A G|389|D PAB1 Poly(A) Binding protein 577.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.2896629451580783 P04147 0.912064015865326 0.9690529704093932 0.9538580179214478 0.0023520053364336486 0.34636828303337097 0.17369601130485535 46.724703114568854 40.0 1.0 no 3480 chrV_511605r 10808 essential YER165W 1235 - ATCTCATTTGATTTCTGGCT R|418|T R|418|K M|417|I M|417|I PAB1 Poly(A) Binding protein 577.0 0 0 0 0 0.11885965802148048 P04147 0.8467410206794739 0.9600319862365724 1.0242600440979004 1.0242600440979004 0.3889847099781037 0.31156986951828003 0.655648946762085 0.655648946762085 47.410943202850206 35.0 1.0 no 3481 chrV_521434 10814 essential YER168C 1216 - ACATATTGAATCTACGGTCT C|412|S C|412|Y CCA1 tRNA CCA-pyrophosphorylase 546.0 0 0 0 0 0.4900345294705517 P21269 0.9421560168266296 0.9290120005607604 0.7241623401641846 0.08143100142478943 42.043410732688415 35.0 0.0 no 3482 chrV_521505 10816 essential YER168C 1145 - TGCTTTCTGTCACCGAAACC S|388|T S|388|N E|387|Q E|387|K CCA1 tRNA CCA-pyrophosphorylase 546.0 0 0 0 0 0.4666987265502389 P21269 0.9512869715690612 0.9536849856376648 0.956179976463318 0.9475290179252625 0.5256627798080444 0.37123963236808777 0.35485103726387024 0.5468357205390929 50.46398044709008 50.0 0.0 no 3483 chrV_521828 10817 essential YER168C 822 - ATCAGCTGCAAAGCCAATAA silent|CTG>CTC|L|280 silent|CTG>CTA|L|280 Q|279|H silent|CAG>CAA|Q|279 CCA1 tRNA CCA-pyrophosphorylase 546.0 0 0 0 1 0.8582577796260895 P21269 0.9570760130882264 0.07300764322280884 44.258420832796624 40.0 0.0 no 3484 chrV_521939 10822 essential YER168C 711 - CCCATTTCAGCCATCACTTC M|243|I M|243|I G|244|R G|244|S CCA1 tRNA CCA-pyrophosphorylase 546.0 0 0 0 0 0.6262637815575259 P21269 0.9553959965705872 0.9553959965705872 0.941340982913971 0.951104998588562 0.0 0.0 0.5762873888015747 0.5460211038589478 55.768342781936504 50.0 0.0 no 3485 chrV_521958r 10823 essential YER168C 689 + ATTCAACTTTACCATAGATC F|231|L silent|TTC>TTT|F|231 N|232|K silent|AAC>AAT|N|232 CCA1 tRNA CCA-pyrophosphorylase 546.0 0 0 0 0 -0.5188971264188577 P21269 0.9387490153312684 0.9439849853515624 0.028637330979108814 0.1628212183713913 39.76690988984228 30.0 0.0 no 3486 chrV_521996 10825 essential YER168C 654 - ATCAACCTCAAAACCCTCAA L|224|F silent|TTG>TTA|L|224 R|223|S silent|AGG>AGA|R|223 CCA1 tRNA CCA-pyrophosphorylase 546.0 0 0 0 0 0.0867378859981256 P21269 0.9587849974632264 0.9087679982185364 0.0 0.0 44.56567397235074 40.0 0.0 no 3487 chrV_521995 10826 essential YER168C 655 - GATCAACCTCAAAACCCTCA L|224|F silent|TTG>TTA|L|224 R|223|S silent|AGG>AGA|R|223 CCA1 tRNA CCA-pyrophosphorylase 546.0 0 0 0 0 0.08995269603528022 P21269 0.9587849974632264 0.9087679982185364 0.0 0.0 47.02434676054953 45.0 0.0 no 3488 chrV_522023 10827 essential YER168C 627 - TCCAAAAATGTTTGTTTTGC L|215|F silent|TTG>TTA|L|215 D|216|H D|216|N CCA1 tRNA CCA-pyrophosphorylase 546.0 0 0 0 0 0.3453058980984212 P21269 0.9587849974632264 0.9486550092697144 0.956179976463318 0.08098028600215912 0.0 0.0 39.511185799108254 30.0 0.0 no 3489 chrV_522154 10831 essential YER168C 496 - CCTTCTTAAAGCGTCTTCCT R|172|T R|172|K R|171|T R|171|K CCA1 tRNA CCA-pyrophosphorylase 546.0 0 0 0 0 -0.7706222989571638 P21269 0.932735025882721 0.955805003643036 0.932735025882721 0.955805003643036 0.0 0.0 0.0 0.0 51.673055349390786 45.0 0.0 no 3490 chrV_522257r 10833 essential YER168C 390 + ACTGCCACTACTAAGCTCTT T|131|S T|131|I A|132|G A|132|V CCA1 tRNA CCA-pyrophosphorylase 546.0 0 0 0 0 -0.3907346143452711 P21269 0.9491789937019348 0.9472420215606691 0.9484469890594482 0.9504740238189696 0.0 0.0 0.0962146669626236 0.06115564331412315 50.880466172358176 45.0 0.0 no 3491 chrV_522253 10834 essential YER168C 397 - AACGCCAAAGAGCTTAGTAG V|139|L V|139|I G|138|A G|138|D CCA1 tRNA CCA-pyrophosphorylase 546.0 0 0 0 0 0.1403180677169422 P21269 0.9539830088615416 0.9574310183525084 0.9499930143356324 0.9446240067481996 0.269597589969635 0.3801442682743073 0.0453953854739666 0.2955183088779449 43.79829557482253 45.0 0.0 no 3492 chrV_522550 10844 essential YER168C 100 - ACAGATGTTCTGTTCCACTT C|40|S C|40|Y CCA1 tRNA CCA-pyrophosphorylase 546.0 0 0 0 0 -0.5160277147511024 P21269 0.9421560168266296 0.9290120005607604 0.5754987597465515 0.07348527759313582 49.6037169220146 40.0 0.0 no 3493 chrV_522556 10846 essential YER168C 94 - GTTCTGTTCCACTTTGGTTA Q|37|H silent|CAG>CAA|Q|37 CCA1 tRNA CCA-pyrophosphorylase 546.0 0 0 0 0 0.8566341681501854 P21269 0.9570760130882264 0.11833057552576065 51.808830034894974 40.0 0.0 no 3494 chrV_527124r 10848 essential YER171W 45 - TACTGCTCTGGATATATCTT Q|21|H silent|CAG>CAA|Q|21 E|20|D silent|GAG>GAA|E|20 RAD3 RADiation sensitive 778.0 0 0 0 0 -2.5160906068051268 P06839 0.00191914604511112 0.01265285536646843 44.76479980048202 35.0 1.0 yes 3495 chrV_527433r 10856 essential YER171W 354 - TTTCGTTCCTTACTCACTTC R|124|P R|124|Q RAD3 RADiation sensitive 778.0 0 0 0 0 -0.03004294251268739 P06839 0.2660095989704132 0.5700768828392029 49.44092629981789 40.0 1.0 no 3496 chrV_527480r 10857 essential YER171W 401 - CCTGCCCATTTGTCATTCTA Q|140|H silent|CAG>CAA|Q|140 silent|GGG>GGC|G|139 silent|GGG>GGA|G|139 RAD3 RADiation sensitive 778.0 0 0 0 0 -1.7316406058063218 P06839 0.23206646740436554 55.43534335734324 45.0 1.0 no 3497 chrV_527749r 10861 essential YER171W 670 - GCTATCTTTAGAAACCTCGT S|230|T S|230|N D|229|H D|229|N RAD3 RADiation sensitive 778.0 0 0 0 0 -3.687405618916837 P06839 0.5577560663223267 0.1131180301308632 0.043841544538736336 0.6102414131164551 45.95909438352585 40.0 1.0 yes 3498 chrV_527822 10862 essential YER171W 740 + GCTGTCATTAGACTTGACAA L|248|V silent|CTG>TTG|L|248 S|249|* S|249|L RAD3 RADiation sensitive 778.0 0 0 0 0 -1.939631584751296 P06839 0.009435037150979042 0.001492357929237187 44.45136706274104 40.0 1.0 no 3499 chrV_527980r 10866 essential YER171W 901 - CACAAATGGCTCTTCCTGGT V|307|L V|307|M RAD3 RADiation sensitive 778.0 0 0 0 0 -1.1908622980849737 P06839 1.0 0.3707515299320221 51.643334042293596 50.0 1.0 no 3500 chrV_528044r 10871 essential YER171W 965 - CGGCTCTTCGTATATTTCCC A|328|P A|328|T R|327|T R|327|K RAD3 RADiation sensitive 778.0 0 0 0 0 -1.0032208037594392 P06839 0.0038985700812190775 0.0026561759877949953 0.2646879553794861 1.0 54.0146884384805 50.0 1.0 no 3501 chrV_528345r 10876 essential YER171W 1266 - GCAGCATTTTCGATTTCATA A|429|P A|429|T A|428|P A|428|T RAD3 RADiation sensitive 778.0 0 0 0 0 0.2829452395057652 P06839 0.2685834169387817 0.6492075920104979 1.0 0.21279162168502808 45.69050277973679 35.0 1.0 no 3502 chrV_528378r 10877 essential YER171W 1299 - AAGCAAGTAAATCTCATAAT C|439|S C|439|Y RAD3 RADiation sensitive 778.0 0 0 0 0 0.8909406440318492 P06839 0.0 0.0 33.80935887360857 25.0 1.0 no 3503 chrV_528442 10879 essential YER171W 1360 + CTTCCGTTATTATCACTTCA S|455|C S|455|F silent|TCC>TCG|S|455 silent|TCC>TCT|S|455 RAD3 RADiation sensitive 778.0 0 0 0 0 0.016568590888470403 P06839 0.0013971434673294425 0.000716024253051728 46.44701722758946 35.0 1.0 no 3504 chrV_528474r 10882 essential YER171W 1395 - ATTCTTGGATACATGTCTAA R|471|T R|471|K RAD3 RADiation sensitive 778.0 0 0 0 0 0.027954371441454292 P06839 0.003866481361910701 1.0 40.47327695890976 30.0 1.0 no 3505 chrV_528558 10885 essential YER171W 1476 + CTACCAATGATTATTACCAA P|494|A P|494|S P|494|R P|494|L RAD3 RADiation sensitive 778.0 0 0 0 0 -0.427112149133258 P06839 0.0 0.0 0.0 0.0 39.707600978027294 30.0 1.0 no 3506 chrV_528627 10887 essential YER171W 1545 + CCTAGTATTGTTCGTAATTA P|516|R P|516|L RAD3 RADiation sensitive 778.0 0 0 0 0 0.7346932597427879 P06839 0.4420776069164276 0.8411608338356018 41.735610269465845 30.0 1.0 no 3507 chrV_531142r 10888 essential YER172C 4857 + TACATTGAAAAGTTAACAGA Y|1620|* silent|TAC>TAT|Y|1620 BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 0.24134566236638602 P32639 32.0099779232757 25.0 0.0 no 3508 chrV_531244 10889 essential YER172C 4758 - TCCATACAATCCTTTCTAGA M|1592|I M|1592|I E|1593|Q E|1593|K BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 -0.08695959995765609 P32639 0.9553959965705872 0.9553959965705872 0.956179976463318 0.9475290179252625 0.7748408317565918 0.7748408317565918 0.5267403721809387 0.8585394620895386 45.73617674000849 35.0 0.0 no 3509 chrV_531844r 10900 essential YER172C 4155 + AATCATTGGAGACAGAATAA H|1387|D H|1387|Y BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 0.7096371539141817 P32639 0.9473130106925964 0.9489949941635132 0.056419942528009415 0.2421053797006607 35.07032762007128 30.0 0.0 no 3510 chrV_531916r 10902 essential YER172C 4083 + TCGAATGACTCGGTCTTTGT S|1362|W S|1362|L BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 0.153955764913496 P32639 0.9288619756698608 0.9298099875450134 0.0075605236925184735 0.03541683778166771 47.539427296982645 45.0 0.0 no 3511 chrV_532036 10906 essential YER172C 3966 - ATACTAATATTCTCCAGAAG S|1328|T S|1328|N BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 -0.3874563366238921 P32639 0.9512869715690612 0.9536849856376648 0.5887055397033691 0.5051952004432678 37.406193327686076 30.0 0.0 no 3512 chrV_532049r 10907 essential YER172C 3950 + TCCTCCTCCTACTCCCCTTC P|1318|R P|1318|L P|1318|A P|1318|S BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 -0.020421518353028568 P32639 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.010783115401864052 0.01616681180894375 0.19906775653362274 0.06778925657272339 66.66038343376505 60.0 0.0 no 3513 chrV_532279r 10911 essential YER172C 3720 + CTCATGCTAGAAGACACTGA silent|CTC>CTG|L|1241 silent|CTC>CTT|L|1241 L|1243|V silent|CTA>TTA|L|1243 BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 -0.6263380884830106 P32639 0.9512209892272948 1.0 44.498779808586114 45.0 0.0 no 3514 chrV_532288 10913 essential YER172C 3714 - TCTTCTAGCATGAGCAAAAA D|1245|H D|1245|N E|1244|Q E|1244|K BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 0.28468377997974165 P32639 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.010194390080869198 0.13611340522766113 0.0 0.0 0.5347999930381775 0.11720000207424165 39.89071684026111 35.0 0.0 no 3515 chrV_532392 10917 essential YER172C 3610 - TGGCTGAGCGTTGCATGTTA Q|1209|H silent|CAG>CAA|Q|1209 BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 0.8578770493343331 P32639 0.9570760130882264 0.0 53.40629001737892 50.0 0.0 no 3516 chrV_532470 10920 essential YER172C 3532 - TCTGATTGCACGACCAACTT R|1184|T R|1184|K BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 0.6897418257326108 P32639 0.932735025882721 0.955805003643036 0.056934371590614326 0.1759202480316162 47.74137737616263 45.0 0.0 no 3517 chrV_532602r 10924 essential YER172C 3397 + AATCTGCCACAACTAAAATG S|1134|C S|1134|F A|1135|G A|1135|V BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 -0.59168989733224 P32639 0.945252001285553 0.9294660091400146 0.9484469890594482 0.9504740238189696 0.11914069205522534 0.08014918863773346 0.005806634668260814 1.0 37.599608997494784 35.0 0.0 no 3518 chrV_532694 10925 essential YER172C 3308 - GCAATAACCTACCAGCATTT L|1109|F silent|TTG>TTA|L|1109 BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 -0.2930148935608169 P32639 0.9587849974632264 0.34349727630615234 47.127993047745406 40.0 0.0 no 3519 chrV_532976r 10928 essential YER172C 3023 + TTACATAAATCATGCTTCCA Y|1009|* silent|TAC>TAT|Y|1009 BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 0.29999058515739985 P32639 41.37098523175007 30.0 0.0 no 3520 chrV_533004 10929 essential YER172C 2998 - CGACGCTATATTTCCTAGAT silent|GCG>GCC|A|1005 silent|GCG>GCA|A|1005 A|1005|P A|1005|T BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 -0.17365462535364012 P32639 0.9573720097541808 0.9523990154266356 0.019406961277127262 0.020002013072371483 45.52854889139331 40.0 0.0 no 3521 chrV_533171 10931 essential YER172C 2831 - AAGCTAACATTCTGACATAT A|950|P A|950|T BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 -0.4536591953744468 P32639 0.9573720097541808 0.9523990154266356 0.2775768041610718 0.5807678699493408 38.51803617391937 30.0 0.0 no 3522 chrV_533368 10932 essential YER172C 2634 - TCGCCAAATGTGTCATATCT G|884|A G|884|D E|885|Q E|885|K BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 -4.255635947949567 P32639 0.9499930143356324 0.9446240067481996 0.956179976463318 0.9475290179252625 0.0 0.0 0.025327473878860474 0.123779758810997 46.71697426120107 40.0 0.0 yes 3523 chrV_533407 10935 essential YER172C 2595 - AACATTTGAAGTACATCTTG M|871|I M|871|I BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 0.3239433452200089 P32639 0.9553959965705872 0.9553959965705872 0.0 0.0 36.60234075703164 30.0 0.0 no 3524 chrV_533442r 10936 essential YER172C 2557 + ATTCACCTGAAAAGGGGTCC S|854|* S|854|L P|855|A P|855|S BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 -3.691187768527025 P32639 0.9298099875450134 0.9562489986419678 0.9498909711837769 0.004747198894619943 0.0 0.0 48.941725319915406 50.0 0.0 yes 3525 chrV_533623r 10940 essential YER172C 2376 + CTACGAAAGTTGATTGAAAG R|794|G R|794|* BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 1.0606880751279233 P32639 0.8994590044021606 0.2642771601676941 33.97887568177015 35.0 0.0 no 3526 chrV_533688 10942 essential YER172C 2314 - CTTCGATCCTGCATCATTTT silent|TCG>TCC|S|777 silent|TCG>TCA|S|777 BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 0.09956685327982276 P32639 49.38971921090484 40.0 0.0 no 3527 chrV_533828r 10943 essential YER172C 2171 + TGCTTGTTATGAAAAGGTAT A|725|G A|725|V BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 -0.3226846537652584 P32639 0.9484469890594482 0.9504740238189696 0.008864403702318668 0.6097820401191711 38.34477569578417 30.0 0.0 no 3528 chrV_533888r 10945 essential YER172C 2111 + TCAACAGTTTTGTGGCATTA Q|705|E Q|705|* Q|706|E Q|706|* BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 0.8264916559486966 P32639 0.9590039849281312 0.9590039849281312 0.0 0.18384799361228946 44.71287143522903 35.0 0.0 no 3529 chrV_533896 10946 essential YER172C 2106 - CCACAAAACTGTTGAGATAG C|708|S C|708|Y G|709|R G|709|S BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 -1.7837657134131062 P32639 0.9421560168266296 0.9290120005607604 0.941340982913971 0.951104998588562 0.035211727023124695 0.021160470321774483 0.006827494129538536 0.14444738626480105 38.991362126216295 40.0 0.0 no 3530 chrV_533980r 10947 essential YER172C 2019 + TTACCAAATTATGAGGATGT P|675|A P|675|S P|675|R P|675|L BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 -0.3972162311500449 P32639 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.0 0.0 0.0 0.0 38.82917136804065 30.0 0.0 no 3531 chrV_533982 10948 essential YER172C 2020 - GACATCCTCATAATTTGGTA V|680|L V|680|I D|679|H D|679|N BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 0.08074653666197268 P32639 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 0.032174669206142426 0.1537240445613861 0.0 0.0 43.92990558817212 35.0 0.0 no 3532 chrV_534040r 10950 essential YER172C 1959 + ACATTTTGGGCTTCCAAATA T|654|R T|654|I BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 0.2443724829929089 P32639 0.9476869702339172 0.9472420215606691 0.06693703681230545 0.17678578197956085 44.814323129971505 35.0 0.0 no 3533 chrV_534092r 10955 essential YER172C 1907 + ACATTTGTTACATGATGACA H|637|D H|637|Y BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 0.6123273471897426 P32639 0.9473130106925964 0.9489949941635132 0.0 0.0 39.64240229773151 30.0 0.0 no 3534 chrV_534093r 10956 essential YER172C 1906 + TACATTTGTTACATGATGAC H|637|D H|637|Y BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 -0.7510373095958458 P32639 0.9473130106925964 0.9489949941635132 0.0 0.0 37.70630350432026 30.0 0.0 no 3535 chrV_534287 10957 essential YER172C 1715 - CCAACCTCCTTTGAAATTCT L|578|F silent|TTG>TTA|L|578 R|577|S silent|AGG>AGA|R|577 BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 0.4702499995039448 P32639 0.9587849974632264 0.9087679982185364 0.0 0.008391207084059715 47.137147451686076 40.0 0.0 no 3536 chrV_534306 10959 essential YER172C 1696 - TCGGACTTGTTCCTGTACTA R|572|P R|572|Q V|571|L V|571|I BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 0.5986518472902852 P32639 0.9099509716033936 0.949662983417511 0.9539830088615416 0.9574310183525084 0.03461997210979462 0.0502784289419651 0.050124414265155785 0.07594917714595795 50.86475900888252 45.0 0.0 no 3537 chrV_534316 10960 essential YER172C 1686 - TCCTGTACTAAGGCTTTCAA Q|568|H silent|CAG>CAA|Q|568 E|569|Q E|569|K BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 -1.8635143471493671 P32639 0.9570760130882264 0.956179976463318 0.9475290179252625 0.0 0.0 0.0 47.2934130412989 40.0 0.0 no 3538 chrV_534435 10963 essential YER172C 1567 - ATTCGTCTTACCTGAACCAG silent|ACG>ACC|T|528 silent|ACG>ACA|T|528 K|527|N silent|AAG>AAA|K|527 BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 0.07566509366548829 P32639 0.9355990290641784 0.0 48.07194946960038 45.0 0.0 no 3539 chrV_534436 10964 essential YER172C 1566 - TTCGTCTTACCTGAACCAGT silent|ACG>ACC|T|528 silent|ACG>ACA|T|528 K|527|N silent|AAG>AAA|K|527 BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 1.023437183440224 P32639 0.9355990290641784 0.0 50.65102877469752 45.0 0.0 no 3540 chrV_534539r 10966 essential YER172C 1460 + TCAGGAGGCGTTTCCTTCAT Q|488|E Q|488|* BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 1.7710424697762712 P32639 0.9590039849281312 0.10162675380706787 55.19896166470744 50.0 0.0 no 3541 chrV_534550 10968 essential YER172C 1452 - AACGCCTCCTGACACCAATC silent|GCG>GCC|A|490 silent|GCG>GCA|A|490 A|490|P A|490|T BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 -2.2385854561665406 P32639 0.9573720097541808 0.9523990154266356 0.022072024643421173 0.016469432041049004 52.53210639982017 55.00000000000001 0.0 yes 3542 chrV_534726 10973 essential YER172C 1276 - AATCTTTTCCAAATCTATGA K|431|N silent|AAG>AAA|K|431 BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 0.7219976903890905 P32639 0.9355990290641784 0.4934968948364258 38.06786905750874 25.0 0.0 no 3543 chrV_534788r 10975 essential YER172C 1211 + TGACGACCAGCCACAGTCTT D|405|E silent|GAC>GAT|D|405 D|406|E silent|GAC>GAT|D|406 BRR2 Bad Response to Refrigeration 2163.0 0 1 0 0 0.7114855959564813 P32639 0.9532920122146606 0.9532920122146606 1.0 1.0 54.93910639657412 55.00000000000001 0.0 no 3544 chrV_534889 10977 essential YER172C 1113 - ACCATTTTCTCTATTAAGTT M|377|I M|377|I V|378|L V|378|I BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 -0.2493644917269997 P32639 0.9553959965705872 0.9553959965705872 0.9539830088615416 0.9574310183525084 0.037234127521514886 0.037234127521514886 0.31014662981033325 0.1977817565202713 41.570923042711 25.0 0.0 no 3545 chrV_535109r 10980 essential YER172C 890 + TCGGTCAGAGCTTGGTTACA R|298|G R|298|W S|299|* S|299|L BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 -1.0558173318331812 P32639 0.8994590044021606 0.9448130130767822 0.9298099875450134 0.4796749949455261 0.08983799815177917 0.31768929958343506 52.54923025613135 50.0 0.0 no 3546 chrV_535324r 10982 essential YER172C 675 + AACAATGCTAATGTTCTTGG N|226|K silent|AAC>AAT|N|226 BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 0.6832628457713799 P32639 0.9439849853515624 0.6572597622871399 39.72716559974015 35.0 0.0 no 3547 chrV_535326r 10984 essential YER172C 673 + CCAACAATGCTAATGTTCTT silent|TCC>TCG|S|225 silent|TCC>TCT|S|225 N|226|K silent|AAC>AAT|N|226 BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 0.8373637364041138 P32639 0.9439849853515624 0.6572597622871399 42.440858407831115 35.0 0.0 no 3548 chrV_535463 10986 essential YER172C 539 - TAACTAATTCGTTAAACTTC V|186|L V|186|I BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 0.8760396282194944 P32639 0.9539830088615416 0.9574310183525084 0.3563772141933441 0.4467419683933258 33.26329302193233 25.0 0.0 no 3549 chrV_535597r 10988 essential YER172C 402 + ATACCCCATGATCTTATTAT P|136|A P|136|S P|136|R P|136|L BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 -0.880950150916585 P32639 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.042511336505413055 0.051567353308200836 0.018857071176171303 0.010273044928908348 45.340323017765066 30.0 0.0 no 3550 chrV_535643r 10990 essential YER172C 356 + TTACGAGCAGATTTTGCAGT Y|120|* silent|TAC>TAT|Y|120 BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 -0.5838857945401824 P32639 46.47804986762014 40.0 0.0 no 3551 chrV_535855 10992 essential YER172C 147 - ATTCTACCACTCATGGATTT R|55|T R|55|K G|54|A G|54|D BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 -0.2571382963642651 P32639 0.932735025882721 0.955805003643036 0.9499930143356324 0.9446240067481996 0.08780090510845184 0.8750334978103638 0.0 0.0 46.03853416042432 35.0 0.0 no 3552 chrV_535848 10993 essential YER172C 154 - AGCACTAATTCTACCACTCA A|58|P A|58|T S|57|T S|57|N BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 -0.24493884044984826 P32639 0.9573720097541808 0.9523990154266356 0.9512869715690612 0.9536849856376648 0.02907460927963257 0.10002759099006653 0.0557103157043457 0.3413380980491638 47.131742622681095 40.0 0.0 no 3553 chrV_535932 10997 essential YER172C 70 - ATCAACTTTCAACACCTTAT D|30|H D|30|N V|29|L V|29|I BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 0.3124718847309953 P32639 0.9486550092697144 0.956179976463318 0.9539830088615416 0.9574310183525084 0.011990339495241642 0.17435894906520846 0.149105504155159 0.15439444780349731 41.246908966344854 30.0 0.0 no 3554 chrV_535896r 10998 essential YER172C 103 + ATACCAGCCAAAATCCTCAA T|36|S T|36|I silent|ACC>ACG|T|36 silent|ACC>ACT|T|36 BRR2 Bad Response to Refrigeration 2163.0 0 0 0 0 -0.4613586304523787 P32639 0.9491789937019348 0.9472420215606691 0.5331286787986755 0.12679368257522586 45.8463190287768 40.0 0.0 no 3555 chrVI_28237r 11000 no_effect YFL052W 8 - AGTCGCACGCTTGTCTATTG D|9|H D|9|N C|8|S C|8|Y 0 0 0 0 -0.7006577265878643 P43551 0.9486550092697144 0.956179976463318 0.9421560168266296 0.9290120005607604 0.0 0.0 0.0 0.0 51.52748583466257 50.0 1.0 no 3556 chrVI_28364r 11002 no_effect YFL052W 135 - TTTCTCACCTTGACGGGTTT R|51|T R|51|K silent|GTG>GTC|V|50 silent|GTG>GTA|V|50 0 0 0 0 0.3722633477694822 P43551 0.932735025882721 0.955805003643036 0.5460042953491211 0.8060086369514465 52.02597967342525 45.0 1.0 no 3557 chrVI_28776 11010 no_effect YFL052W 544 + CCAACTCAAGAACTTCGTAT silent|TCC>TCG|S|182 silent|TCC>TCT|S|182 N|183|K silent|AAC>AAT|N|183 0 0 0 0 0.3433733595441878 P43551 0.9439849853515624 0.9090129733085632 42.51171993729861 40.0 1.0 no 3558 chrVI_28982r 11022 no_effect YFL052W 753 - TCCGTTACGTTCTCCGGTTG silent|ACG>ACC|T|257 silent|ACG>ACA|T|257 D|258|H D|258|N 0 0 0 0 0.5151333235479439 P43551 0.9486550092697144 0.956179976463318 0.09462720900774002 0.2398015409708023 55.62461235180014 55.00000000000001 1.0 no 3559 chrVI_29011 11025 no_effect YFL052W 779 + ACTATCTCTCGACAGCTTCT L|261|V silent|CTA>TTA|L|261 S|262|C S|262|F 0 0 0 0 0.5733800272394681 P43551 0.9512209892272948 0.945252001285553 0.9294660091400146 0.08858099579811096 0.18033288419246676 50.66431326100843 45.0 1.0 no 3560 chrVI_29272r 11034 no_effect YFL052W 1043 - GCGTATTCTTGCTATTTGAA silent|ACG>ACC|T|354 silent|ACG>ACA|T|354 0 0 0 0 1.064441148989177 P43551 44.51034156414481 35.0 1.0 no 3561 chrVI_42906r 11036 no_effect YFL046W 94 - ATCTTTAAAGTGGTTCGTAT D|38|H D|38|N FMP32 Found in Mitochondrial Proteome 207.0 0 0 0 0 0.9687798549831166 P43557 0.024175668135285374 0.0956939160823822 40.80521910903325 30.0 1.0 no 3562 chrVI_43054r 11041 no_effect YFL046W 242 - CACGTTGTTGATAGCTAAGT R|87|P R|87|H FMP32 Found in Mitochondrial Proteome 207.0 0 0 0 0 -7.005880359785039 P43557 0.0035478493664413686 0.004029722884297371 44.46589664125378 40.0 1.0 yes 3563 chrVI_43815r 11045 essential YFL045C 555 + TCTTTCGACGTTTTCCCCGC S|186|C S|186|F F|187|L silent|TTC>TTT|F|187 SEC53 SECretory 254.0 0 0 0 0 -0.4643228538456581 P07283 0.0 0.0 0.11828704178333282 57.43022985164885 55.00000000000001 0.0 no 3564 chrVI_43848r 11047 essential YFL045C 522 + TACGGTTTGACTTTCTCCAT Y|175|* silent|TAC>TAT|Y|175 SEC53 SECretory 254.0 0 0 0 0 -1.0450037671791832 P07283 48.75669143382714 40.0 0.0 no 3565 chrVI_43886 11048 essential YFL045C 487 - TTTCAAAGCTTCAACGAACT L|168|F silent|TTG>TTA|L|168 SEC53 SECretory 254.0 0 1 0 0 -0.3923413689001785 P07283 0.03277655318379402 39.629859746477905 35.0 0.0 no 3566 chrVI_43998r 11050 essential YFL045C 372 + ACTTTCTTGGAATTTAGAAA T|125|S T|125|I F|126|L silent|TTC>TTT|F|126 SEC53 SECretory 254.0 0 1 0 0 -0.06666038062006767 P07283 0.11572454124689102 0.008610142394900322 0.0 -1.0200799703598022 35.611808622962776 25.0 0.0 no 3567 chrVI_44337 11057 essential YFL045C 36 - TCGAATAAAACCAAAGTTTC D|19|H D|19|N SEC53 SECretory 254.0 1 Series([], Name: modification, dtype: object) 0 0 0 -1.4567447528976714 P07283 0.0 0.0 34.14278394870661 30.0 0.0 no 3568 chrVI_44365r 11058 essential YFL045C 5 + TATCGCTGAATTCGCTTACA I|3|M silent|ATC>ATT|I|3 A|4|G A|4|V SEC53 SECretory 254.0 0 1 0 0 0.4106803582121728 P07283 45.4016272206851 40.0 0.0 no 3569 chrVI_53524 11060 essential YFL039C 799 - ATCGACATCACACTTCATGA D|273|H D|273|N V|272|L V|272|I ACT1 ACTin 375.0 0 0 0 0 -4.09659489662341 P60010 44.482786394954026 40.0 0.0 yes 3570 chrVI_53580r 11061 essential YFL039C 740 + CCATCCTTCTGTTTTGGGTT H|248|D H|248|Y P|249|A P|249|S ACT1 ACTin 375.0 0 0 0 0 0.8164685123389117 P60010 55.49503181399446 45.0 0.0 no 3571 chrVI_53932 11064 essential YFL039C 391 - AACAATACCAGTAGTTCTAC V|137|L V|137|I ACT1 ACTin 375.0 0 0 0 0 -5.599322291306744 P60010 40.525871043433476 35.0 0.0 yes 3572 chrVI_54033 11068 essential YFL039C 290 - TCTTTTCTCTGTTTGATTTA K|103|N silent|AAG>AAA|K|103 E|102|Q E|102|K ACT1 ACTin 375.0 0 0 0 0 0.37326670760462777 P60010 42.41878514870035 25.0 0.0 no 3573 chrVI_54032 11069 essential YFL039C 291 - ATCTTTTCTCTGTTTGATTT K|103|N silent|AAG>AAA|K|103 ACT1 ACTin 375.0 0 0 0 0 -0.2346965053415101 P60010 43.024863372711316 25.0 0.0 no 3574 chrVI_54151r 11074 essential YFL039C 169 + AACACGGTATTGTCACCAAC H|58|D H|58|Y H|58|Q silent|CAC>CAT|H|58 ACT1 ACTin 375.0 0 1 0 0 0.2974069050659053 P60010 45.07950257996493 45.0 0.0 no 3575 chrVI_54167r 11076 essential YFL039C 153 + TTACGTTACCCAATTGAACA R|53|G R|53|C ACT1 ACTin 375.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.6149402718295258 P60010 42.6742125965771 35.0 0.0 no 3576 chrVI_54281r 11084 essential YFL039C 39 + GCTGTCTTCCCATCTATCGT A|14|G A|14|V silent|GTC>GTG|V|15 silent|GTC>GTT|V|15 ACT1 ACTin 375.0 0 1 0 0 -0.6733353866658219 P60010 57.84578871658306 50.0 0.0 no 3577 chrVI_55681 11091 essential YFL038C 286 - CCACATCTTCACGCCGTTGA M|101|I M|101|I W|102|S W|102|* YPT1 Yeast Protein Two 206.0 0 0 0 0 -0.6932596272455755 P01123 0.8237619996070862 0.8237619996070862 0.5976409912109375 0.1821648180484772 0.1821648180484772 0.0 0.8251799941062927 0.8251799941062927 4.107180118560791 0.985360026359558 0.985360026359558 55.15600730451155 55.00000000000001 0.0 no 3578 chrVI_55748r 11093 essential YFL038C 216 + ATCACTTCATCTTACTACCG I|73|M silent|ATC>ATT|I|73 T|74|S T|74|I YPT1 Yeast Protein Two 206.0 0 0 0 0 -0.4743395521537029 P01123 0.7808970212936401 0.7081810235977173 0.5773419737815857 0.0225916039198637 0.004272185731679201 0.0016093278536573052 0.046620000153779984 0.6530799865722656 0.10350000113248824 -1.0172400474548342 0.04370000958442688 0.5171999931335449 -1.356299877166748 46.07935826372892 40.0 0.0 no 3579 chrVI_56377 11100 essential YFL037W 41 + CCAAATTGGTGCTGCATTCT Q|15|E Q|15|* TUB2 TUBulin 457.0 0 0 0 0 0.6640748205742679 P02557 0.03238969296216965 -0.294979989528656 49.847498556429 45.0 1.0 no 3580 chrVI_56404 11103 essential YFL037W 68 + TATCTGTGGTGAGCACGGTT I|24|M silent|ATC>ATT|I|24 TUB2 TUBulin 457.0 0 0 0 0 -1.972306561882544 P02557 0.036730345338582986 0.6716200113296509 52.3516091064318 50.0 1.0 no 3581 chrVI_56483 11105 essential YFL037W 147 + TACTTCAACGAGGCATCTTC Y|50|* silent|TAC>TAT|Y|50 F|51|L silent|TTC>TTT|F|51 TUB2 TUBulin 457.0 0 0 0 0 -0.3703738024909892 P02557 0.006671386305242778 1.4952199459075928 46.340923505094224 45.0 1.0 no 3582 chrVI_56605 11108 essential YFL037W 269 + TATCTTTGGGCAAAGTTCTG I|91|M silent|ATC>ATT|I|91 TUB2 TUBulin 457.0 0 0 0 0 0.7134527736271763 P02557 0.013397468253970146 1.6814600229263306 0.8122000098228455 44.34248728507407 40.0 1.0 no 3583 chrVI_56640r 11113 essential YFL037W 307 - ACCTTCTGTGTAGTGACCCT G|109|R G|109|S G|109|A G|109|D TUB2 TUBulin 457.0 0 0 0 0 -6.444645235875268 P02557 0.0025855535641312604 0.007274238392710686 0.010698960162699224 0.00727941608056426 17.794679641723633 8.403840065002441 2.9463000297546387 17.188199996948242 57.167293730627996 50.0 1.0 yes 3584 chrVI_56763r 11114 essential YFL037W 430 - AAGCGTACCCATACCGGAAC silent|ACG>ACC|T|149 silent|ACG>ACA|T|149 TUB2 TUBulin 457.0 0 0 0 0 -3.7572142324513607 P02557 50.67982290793765 55.00000000000001 1.0 yes 3585 chrVI_56952 11118 essential YFL037W 616 + CACTTTATGACATCTGTCAA L|207|V L|207|F TUB2 TUBulin 457.0 0 0 0 0 0.11361980875856292 P02557 0.06715646386146545 0.042776912450790405 1.6731400489807131 7.1719398498535165 41.787311470354716 35.0 1.0 no 3586 chrVI_57044 11119 essential YFL037W 708 + ACAACTTCATTGCGTTATCC T|237|R T|237|I T|238|S T|238|I TUB2 TUBulin 457.0 0 0 0 0 0.22355179728496016 P02557 0.0014449837617576122 0.0017615489196032286 0.3000788986682892 0.007629309780895709 2.412359952926636 2.687160015106201 0.9642000198364258 0.1081399992108345 46.438727899203464 40.0 1.0 no 3587 chrVI_57115 11121 essential YFL037W 779 + CCCACGTTTACATTTCTTCA P|261|R P|261|L P|261|A P|261|S TUB2 TUBulin 457.0 0 0 0 0 -1.4716346876045383 P02557 0.038294583559036255 0.0017517965752631426 0.01322873681783676 0.05591651424765587 1.9442000389099119 1.872040033340454 1.8260999917984009 2.203939914703369 0.3694999814033508 1.1306999921798706 1.0860999822616575 1.486600041389465 49.91810162810003 40.0 1.0 no 3588 chrVI_57115r 11122 essential YFL037W 782 - CCATGAAGAAATGTAAACGT M|267|I M|267|I TUB2 TUBulin 457.0 0 0 0 0 -0.5692841080378188 P02557 0.566421627998352 0.566421627998352 2.1267800331115723 2.1267800331115723 36.603211258340025 35.0 1.0 no 3589 chrVI_57193r 11126 essential YFL037W 860 - ACATTTGCTGTGTTAATTCA M|293|I M|293|I TUB2 TUBulin 457.0 0 0 0 0 0.01807859823901209 P02557 0.2908838391304016 0.2908838391304016 3.4346399307250977 3.4346399307250977 42.679316637389256 30.0 1.0 no 3590 chrVI_57300r 11129 essential YFL037W 967 - TTCATCTTCCACCTCCTTAA E|329|Q E|329|K D|328|H D|328|N TUB2 TUBulin 457.0 0 0 0 0 -2.157625319899089 P02557 1.0 0.25925949215888977 0.043390385806560516 0.2289468348026276 -0.5299199819564819 -0.4944599866867066 0.08628000319004059 -0.13561999797821045 0.7554000020027161 -0.15520000457763672 51.925634921487465 40.0 1.0 yes 3591 chrVI_78333r 11131 essential YFL029C 806 + TTGCTCAATATTCGAAAAGT C|270|W silent|TGC>TGT|C|270 S|271|* S|271|L CAK1 Cdk-Activating Kinase 368.0 0 0 0 0 -0.7201629840464324 P43568 0.9286419749259948 0.9298099875450134 0.09702327847480774 0.006360648665577172 37.388131781315046 30.0 0.0 no 3592 chrVI_78426 11138 essential YFL029C 716 - CCATACGGCTTGTTTCTCTC M|245|I M|245|I R|244|P R|244|H CAK1 Cdk-Activating Kinase 368.0 0 0 0 0 0.052349137527879085 P43568 0.9553959965705872 0.9553959965705872 0.9099509716033936 0.9570810198783876 0.20217010378837585 0.20217010378837585 0.35530516505241394 0.3916781842708588 53.547412142328426 50.0 0.0 no 3593 chrVI_78508 11141 essential YFL029C 634 - TACTCCAAAAAGCACTTCTG V|218|L V|218|I G|217|A G|217|E CAK1 Cdk-Activating Kinase 368.0 0 0 0 0 -0.27204501692509164 P43568 0.9539830088615416 0.9574310183525084 0.9499930143356324 0.9438679814338684 0.035834640264511115 0.17810921370983124 0.12172680348157885 0.020034322515130043 41.553182813731105 40.0 0.0 no 3594 chrVI_78554 11142 essential YFL029C 588 - TCCGTCACCTTGCTATCCAT silent|ACG>ACC|T|202 silent|ACG>ACA|T|202 D|203|H D|203|N CAK1 Cdk-Activating Kinase 368.0 0 0 0 1 -0.28081344522197804 P43568 0.9486550092697144 0.956179976463318 0.0 0.0 57.285163169343605 50.0 0.0 no 3595 chrVI_78624 11145 essential YFL029C 518 - AATCAATTATGTACAACTTT D|179|H D|179|N CAK1 Cdk-Activating Kinase 368.0 0 0 0 0 -0.4270937476165049 P43568 0.9486550092697144 0.956179976463318 0.0 0.0 33.60966852804904 20.0 0.0 no 3596 chrVI_78625 11146 essential YFL029C 517 - ATCAATTATGTACAACTTTG D|179|H D|179|N CAK1 Cdk-Activating Kinase 368.0 0 0 0 0 -2.7050704475634992 P43568 0.9486550092697144 0.956179976463318 0.0 0.0 34.880365226537826 25.0 0.0 yes 3597 chrVI_78931 11151 essential YFL029C 211 - CAACAATAGGTCATTATTAT L|76|F silent|TTG>TTA|L|76 CAK1 Cdk-Activating Kinase 368.0 0 0 0 0 -0.5943142906644321 P43568 0.9587849974632264 0.060359727591276176 35.54874487773486 25.0 0.0 no 3598 chrVI_79122r 11154 essential YFL029C 17 + AGACATTACACACTGTCAGT D|7|E silent|GAC>GAT|D|7 CAK1 Cdk-Activating Kinase 368.0 0 0 0 0 0.009352935862086936 P43568 0.9532920122146606 45.18023859409283 40.0 0.0 no 3599 chrVI_88550r 11157 essential YFL024C 1773 + ATCAGAATATATGATTCAAA I|592|M silent|ATC>ATT|I|592 EPL1 Enhancer of Polycomb Like 832.0 0 0 0 0 0.9027359205860352 P43572 0.9598389863967896 0.196548193693161 31.496753615633335 20.0 0.0 no 3600 chrVI_88587r 11158 essential YFL024C 1736 + ACATTTACCAGAATACTTGA H|580|D H|580|Y EPL1 Enhancer of Polycomb Like 832.0 0 0 0 0 -0.2228460765115904 P43572 0.9473130106925964 0.9489949941635132 1.0 0.06201238930225372 39.64433420466338 30.0 0.0 no 3601 chrVI_89251 11170 essential YFL024C 1075 - TTCATCATTAATCCAATTTA E|365|Q E|365|K D|364|H D|364|N EPL1 Enhancer of Polycomb Like 832.0 0 0 0 0 0.2853118861115781 P43572 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.08193506300449371 0.08196084946393968 0.12089785933494568 0.5027574300765991 37.01996661177515 20.0 0.0 no 3602 chrVI_89250 11171 essential YFL024C 1076 - ATTCATCATTAATCCAATTT E|365|Q E|365|K D|364|H D|364|N EPL1 Enhancer of Polycomb Like 832.0 0 0 0 0 0.2424704761186225 P43572 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.08193506300449371 0.08196084946393968 0.12089785933494568 0.5027574300765991 37.56219105705776 20.0 0.0 no 3603 chrVI_89281 11173 essential YFL024C 1045 - CTCACGTTTAGCAACAAGCA E|355|Q E|355|K R|354|P R|354|H EPL1 Enhancer of Polycomb Like 832.0 0 1 0 0 -0.4615653009826575 P43572 0.956179976463318 0.9475290179252625 0.9099509716033936 0.9570810198783876 0.0 0.0 0.0 0.0 46.21791069543372 45.0 0.0 no 3604 chrVI_89341r 11174 essential YFL024C 982 + TCTTAAACAGTCAGCGTTTA I|328|M silent|ATC>ATT|I|328 EPL1 Enhancer of Polycomb Like 832.0 0 0 0 0 0.1078495664174814 P43572 0.9598389863967896 0.08366405963897705 42.75164186503059 35.0 0.0 no 3605 chrVI_89402 11176 essential YFL024C 924 - CTTCTTCTGAAACAGACGTA R|314|T R|314|K R|313|T R|313|K EPL1 Enhancer of Polycomb Like 832.0 0 0 0 0 -1.6817279772000142 P43572 0.932735025882721 0.955805003643036 0.932735025882721 0.955805003643036 0.00814687181264162 0.04969572275876999 0.0 0.0 42.070827481478936 40.0 0.0 no 3606 chrVI_89426 11178 essential YFL024C 900 - TCAATCTCTTCTTTTTCACC D|307|H D|307|N E|305|D silent|GAG>GAA|E|305 EPL1 Enhancer of Polycomb Like 832.0 0 0 0 0 0.9821069520374364 P43572 0.9486550092697144 0.956179976463318 0.94931298494339 0.00761337811127305 0.1137256771326065 1.0 46.40439117659661 35.0 0.0 no 3607 chrVI_89537 11181 essential YFL024C 789 - TTCTCTATCAGCTGAATTAA E|269|D silent|GAG>GAA|E|269 E|269|Q E|269|K EPL1 Enhancer of Polycomb Like 832.0 0 0 0 0 -0.7121839989617273 P43572 0.94931298494339 0.956179976463318 0.9475290179252625 0.18903735280036926 0.025225017219781883 0.02078360319137573 40.126736634047525 30.0 0.0 no 3608 chrVI_89845 11187 essential YFL024C 481 - TCTTTCATCCATATTGTAGT R|167|T R|167|K E|166|Q E|166|K EPL1 Enhancer of Polycomb Like 832.0 0 0 0 0 -0.2317202953064069 P43572 0.932735025882721 0.955805003643036 0.956179976463318 0.9475290179252625 0.5639666318893433 0.9201831221580504 0.0 0.0 45.29093611583494 30.0 0.0 no 3609 chrVI_89956 11190 essential YFL024C 370 - CCAAGTCATAGAAGCATCCG W|130|S W|130|* M|128|I M|128|I EPL1 Enhancer of Polycomb Like 832.0 0 0 0 0 0.3007873191105197 P43572 0.8858469724655151 0.9553959965705872 0.9553959965705872 0.0 0.14157868921756744 0.14157868921756744 47.81885260927481 50.0 0.0 no 3610 chrVI_90227r 11196 essential YFL024C 96 + GGTCTAGATTCATTCTCAAA L|34|V silent|CTA>TTA|L|34 EPL1 Enhancer of Polycomb Like 832.0 0 0 0 0 0.09873009173965423 P43572 0.9512209892272948 42.4300358284242 35.0 0.0 no 3611 chrVI_90277r 11199 essential YFL024C 46 + AATCTGGTAGAAGCACTAGG S|17|C S|17|F EPL1 Enhancer of Polycomb Like 832.0 0 0 0 0 0.14106667273607065 P43572 0.945252001285553 0.9294660091400146 43.79788560854047 45.0 0.0 no 3612 chrVI_94118 11219 essential YFL022C 873 - TCCATGTATGTCTTGTCATC M|297|I M|297|I D|298|H D|298|N 0 1 0 0 0.029306029793861214 P15625 1.0282399654388428 1.0282399654388428 0.9651989936828612 1.0199799537658691 0.2283681035041809 0.2283681035041809 0.07623065263032912 0.2809291779994965 1.4138000011444092 1.4138000011444092 49.146376344397936 40.0 0.0 no 3613 chrVI_94261 11226 essential YFL022C 730 - GGGCATCTCTGTGAATCCCA M|249|I M|249|I E|248|D silent|GAG>GAA|E|248 0 0 0 0 -1.1773556842705226 P15625 0.907164990901947 0.907164990901947 0.6027560234069824 0.0 0.0 0.0 1.6640000343322754 1.6640000343322754 56.87471232326209 55.00000000000001 0.0 no 3614 chrVI_94304 11227 essential YFL022C 687 - TCCTCTCTGACTTTGTTTAA E|235|D silent|GAG>GAA|E|235 E|236|Q E|236|K 0 1 0 0 -0.28625461794945706 P15625 0.9894880056381226 0.992467999458313 0.9448779821395874 0.4697931408882141 0.3470129072666168 0.022012419998645786 46.53260590239603 35.0 0.0 no 3615 chrVI_94355r 11228 essential YFL022C 633 + CCTTACAATTTCAATTCTCA P|212|R P|212|L Y|213|* silent|TAC>TAT|Y|213 0 1 0 0 0.7285529333388869 P15625 0.9157339930534364 0.8655940294265747 0.13628098368644714 0.13205888867378235 41.54057367819075 30.0 0.0 no 3616 chrVI_94305 11229 essential YFL022C 686 - CCTCTCTGACTTTGTTTAAG E|235|Q E|235|K E|235|D silent|GAG>GAA|E|235 0 1 0 0 0.0764051769307863 P15625 0.9902740120887756 0.9426329731941224 0.9894880056381226 0.5279290676116943 0.8191457390785217 0.4697931408882141 45.548474493276956 40.0 0.0 no 3617 chrVI_94384 11230 essential YFL022C 607 - CTTCAAGTCCTTGTATGCAT L|208|F silent|TTG>TTA|L|208 0 1 0 0 0.4708772090485862 P15625 0.964892029762268 0.09888596832752228 -0.30059999227523804 48.64835893822942 40.0 0.0 no 3618 chrVI_94437r 11231 essential YFL022C 551 + CTCGACCGACCTCACCAAAT S|185|W S|185|L T|186|S T|186|I 0 0 0 0 -0.03941219299540817 P15625 0.6552900075912476 0.8434140086174011 0.9576539993286132 0.955632984638214 0.004064173903316259 0.06470295041799545 0.628413200378418 0.17622476816177368 51.12586889665164 55.00000000000001 0.0 no 3619 chrVI_94428 11232 essential YFL022C 563 - GATCGGTTTCCAATTTGGTG D|194|H D|194|N 0 0 0 0 -0.6381093906952431 P15625 0.8519889712333679 0.96111798286438 0.002076159929856658 0.005402494221925736 48.10170639442129 45.0 0.0 no 3620 chrVI_94557r 11234 essential YFL022C 431 + AATCAAGAACAACTCGCATC I|145|M silent|ATC>ATT|I|145 0 1 0 0 -0.4002224221061376 P15625 0.9878270030021667 0.03176553174853325 -2.8136000633239746 39.347365867093394 40.0 0.0 no 3621 chrVI_94603 11235 essential YFL022C 388 - ATCAGTAAGCTCATTTAAAT D|136|H D|136|N 0 0 0 0 0.7831210321402359 P15625 0.7215549945831299 0.8757920265197754 0.00356636312790215 0.052948985248804085 36.76450963560456 25.0 0.0 no 3622 chrVI_94710r 11238 essential YFL022C 278 + ACTGGGTCCTCAAGTTGGTA L|94|V silent|CTG>TTG|L|94 0 1 0 0 -0.21043658526107167 P15625 1.0151200294494631 1.0 0.08500000089406967 54.02800595097682 50.0 0.0 no 3623 chrVI_94764r 11241 essential YFL022C 224 + AGTCAAGCTCATCCAAGAGT silent|GTC>GTG|V|76 silent|GTC>GTT|V|76 0 0 0 0 0.4919660120551019 P15625 49.119797058022975 45.0 0.0 no 3624 chrVI_94914 11243 essential YFL022C 77 - CATCTTGAGAGCCGTGCTGA D|32|H D|32|N 0 0 0 0 -0.7583317802992896 P15625 0.8481460213661194 0.9980859756469728 0.10349071770906447 0.4405026435852051 54.07315411100012 55.00000000000001 0.0 no 3625 chrVI_104141r 11247 essential YFL017C 299 + TGCAGTAAACTCCAAGTATC A|101|G A|101|V GNA1 GlucosamiNe-6-phosphate Acetyltransferase 159.0 0 0 0 0 -0.3840640786669488 P43577 0.7461109757423401 0.8570690155029297 0.01520939543843269 0.11226247251033784 1.8458499908447263 1.324571967124939 43.07128685644108 40.0 0.0 no 3626 chrVI_104251 11253 essential YFL017C 192 - CGCTTGTCCACAATCACCAT K|70|N silent|AAG>AAA|K|70 GNA1 GlucosamiNe-6-phosphate Acetyltransferase 159.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.6049409434341795 P43577 0.9528689980506896 0.5016114115715027 1.0571140050888062 52.47588846212574 50.0 0.0 no 3627 chrVI_104430 11259 essential YFL017C 13 - TCGCCTTATATAAAATCCAT R|10|S silent|AGG>AGA|R|10 R|11|P R|11|Q GNA1 GlucosamiNe-6-phosphate Acetyltransferase 159.0 0 0 0 0 -0.47336542221724 P43577 0.5528439879417419 0.878915011882782 0.7883009910583496 0.004295899532735348 1.0 0.03595080226659775 4.30036211013794 1.3328759670257568 2.657965898513794 41.274907389632226 30.0 0.0 no 3628 chrVI_116193r 11265 essential YFL009W 51 - CCAGACACACGGTAGCTATA invalid seq invalid seq invalid seq invalid seq CDC4 Cell Division Cycle 779.0 0 0 0 0 -0.8712744596281599 P07834 49.5142925857092 50.0 1.0 no 3629 chrVI_116227r 11266 essential YFL009W 85 - AAGCGCAGTAACACTACCTG invalid seq invalid seq invalid seq invalid seq CDC4 Cell Division Cycle 779.0 0 0 0 0 0.707429404907435 P07834 47.52155168492834 50.0 1.0 no 3630 chrVI_116204r 11267 essential YFL009W 62 - AAGCTATACCGCCAGACACA invalid seq invalid seq invalid seq invalid seq CDC4 Cell Division Cycle 779.0 0 0 0 0 -1.4014934038674824 P07834 50.76266583120634 50.0 1.0 no 3631 chrVI_116424 11271 essential YFL009W 279 + CCAGTTAACTTACAGAACAC invalid seq invalid seq invalid seq invalid seq CDC4 Cell Division Cycle 779.0 0 0 0 0 0.1158022495869384 P07834 40.964410574868566 40.0 1.0 no 3632 chrVI_116654 11276 essential YFL009W 509 + TGCTACTATTAACAATCCTA invalid seq invalid seq invalid seq invalid seq CDC4 Cell Division Cycle 779.0 0 0 0 0 0.6646943327184511 P07834 40.50946170996377 30.0 1.0 no 3633 chrVI_116697 11279 essential YFL009W 552 + TCACCCACTGCTTCCTCTCC invalid seq invalid seq invalid seq invalid seq CDC4 Cell Division Cycle 779.0 0 0 0 0 -0.33816595378826303 P07834 63.502240435128726 60.0 1.0 no 3634 chrVI_116811r 11282 essential YFL009W 669 - ATCTCATCAGAAAGGTATTC invalid seq invalid seq invalid seq invalid seq CDC4 Cell Division Cycle 779.0 0 0 0 0 -0.5398396874885669 P07834 40.292173886711225 35.0 1.0 no 3635 chrVI_116924 11284 essential YFL009W 779 + CGACTTGGGGACTTTAATCA invalid seq invalid seq invalid seq invalid seq CDC4 Cell Division Cycle 779.0 0 0 0 0 0.1977339235403001 P07834 45.55128610602145 45.0 1.0 no 3636 chrVI_117002 11286 essential YFL009W 857 + TTTCAATTATTTGCAATTCG invalid seq invalid seq invalid seq invalid seq CDC4 Cell Division Cycle 779.0 0 0 0 0 0.4179727674619813 P07834 37.030742333302896 25.0 1.0 no 3637 chrVI_117393 11287 essential YFL009W 1248 + CAACTATCAGGTCATGATGG invalid seq invalid seq invalid seq invalid seq CDC4 Cell Division Cycle 779.0 0 0 0 0 0.17605118073448356 P07834 43.881446205377415 45.0 1.0 no 3638 chrVI_119484r 11289 essential YFL008W 58 - CGACTCGCCGAATCCTACCT E|25|D silent|GAG>GAA|E|25 E|25|Q E|25|K SMC1 Stability of MiniChromosomes 1225.0 0 0 0 0 0.11513677855068327 P32908 0.94931298494339 0.956179976463318 0.9475290179252625 0.6900457143783569 0.2993634343147278 0.4347332715988159 -0.34279999136924744 0.3135200142860413 0.13048000633716586 55.16732681735141 60.0 1.0 no 3639 chrVI_119692 11294 essential YFL008W 263 + CCCACAATCCGCATACGTGA P|89|R P|89|L P|89|A P|89|S SMC1 Stability of MiniChromosomes 1225.0 0 1 0 0 0.3095286149614522 P32908 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.04640154540538788 0.06927694380283356 0.3257763087749481 0.3759338557720184 -0.26330000162124634 -0.3578599989414215 -0.10797999799251556 0.2353599965572357 53.152242177913934 55.00000000000001 1.0 no 3640 chrVI_119722 11298 essential YFL008W 293 + TCAAAAAGGTAACAAACTGG Q|99|E Q|99|* SMC1 Stability of MiniChromosomes 1225.0 0 1 0 0 -0.1666935063346104 P32908 0.9590039849281312 1.0 0.31407999992370605 33.30748480426695 35.0 1.0 no 3641 chrVI_119774 11300 essential YFL008W 345 + GACACTAGTTATAAAATTGA D|116|E silent|GAC>GAT|D|116 T|117|S T|117|I SMC1 Stability of MiniChromosomes 1225.0 0 0 0 0 0.4262710185563655 P32908 0.9532920122146606 0.9491789937019348 0.9472420215606691 0.7653904557228088 1.0 0.013158449903130531 -0.404119998216629 0.4066399931907654 2.209820032119751 33.03131828355316 25.0 1.0 no 3642 chrVI_119913r 11301 essential YFL008W 487 - AAACATTCTTGATAATTCTA M|168|I M|168|I SMC1 Stability of MiniChromosomes 1225.0 0 0 0 0 0.4430233016624889 P32908 0.9553959965705872 0.9553959965705872 0.10940108448266984 0.10940108448266984 1.1154199838638306 1.1154199838638306 33.298899371803714 20.0 1.0 no 3643 chrVI_120208 11306 essential YFL008W 779 + CTCTGAAATATCGTCTTTAA S|261|C S|261|F SMC1 Stability of MiniChromosomes 1225.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.4326894558781402 P32908 0.945252001285553 0.9294660091400146 0.053737644106149667 0.06306701898574829 37.688797353419204 30.0 1.0 no 3644 chrVI_120209 11307 essential YFL008W 780 + TCTGAAATATCGTCTTTAAA S|261|C S|261|F SMC1 Stability of MiniChromosomes 1225.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.41228960097104816 P32908 0.945252001285553 0.9294660091400146 0.053737644106149667 0.06306701898574829 34.71043178923805 25.0 1.0 no 3645 chrVI_120276r 11309 essential YFL008W 850 - TACTGCGCTTTCTTTAACAA V|290|L V|290|I A|289|P A|289|T SMC1 Stability of MiniChromosomes 1225.0 0 0 0 0 0.11438193125358055 P32908 0.9539830088615416 0.9574310183525084 0.9573720097541808 0.9523990154266356 0.3488755226135254 0.2356977015733719 0.34223729372024536 0.6854225993156433 43.35060863424411 35.0 1.0 no 3646 chrVI_120651r 11311 essential YFL008W 1225 - TCGCTTATCGTTGTTCAAAA K|414|N silent|AAG>AAA|K|414 R|415|P R|415|Q SMC1 Stability of MiniChromosomes 1225.0 0 0 0 0 -0.2521535840057469 P32908 0.9355990290641784 0.9099509716033936 0.949662983417511 0.19128993153572085 0.26506325602531433 0.5955930948257446 42.2547788922605 35.0 1.0 no 3647 chrVI_120501r 11312 essential YFL008W 1075 - TTCAAAAGCTTCCTTTGATC E|365|Q E|365|K SMC1 Stability of MiniChromosomes 1225.0 0 0 0 0 1.4229433004300387 P32908 0.956179976463318 0.9475290179252625 0.2332519292831421 0.16173627972602844 42.3914856176296 35.0 1.0 no 3648 chrVI_120885 11317 essential YFL008W 1456 + ACGACTTAAATTTCAAGTTG Y|486|* silent|TAC>TAT|Y|486 D|487|E silent|GAC>GAT|D|487 SMC1 Stability of MiniChromosomes 1225.0 0 0 0 0 0.047063159313810936 P32908 0.9532920122146606 1.0 35.7468953941447 30.0 1.0 no 3649 chrVI_121184r 11320 essential YFL008W 1758 - TCTGTCTCAATTGTGTCTAG E|593|Q E|593|K E|591|D silent|GAG>GAA|E|591 SMC1 Stability of MiniChromosomes 1225.0 0 0 0 0 -0.6541807892802469 P32908 0.956179976463318 0.9475290179252625 0.94931298494339 0.3896695971488953 0.5757606029510498 0.725691020488739 45.86917945894015 40.0 1.0 no 3650 chrVI_121122r 11321 essential YFL008W 1696 - TGCAATGCATTCTTGAGCTA A|572|P A|572|T SMC1 Stability of MiniChromosomes 1225.0 0 0 0 0 -0.5833723131434603 P32908 0.9573720097541808 0.9523990154266356 0.26037901639938354 0.6007592082023621 47.15796351643086 40.0 1.0 no 3651 chrVI_121006r 11324 essential YFL008W 1580 - GAACAAGACCTTTTACTCCG V|533|L V|533|I SMC1 Stability of MiniChromosomes 1225.0 0 0 0 0 0.24112400342186724 P32908 0.9539830088615416 0.9574310183525084 0.2036980837583542 0.11084058880805968 45.04557734000679 45.0 1.0 no 3652 chrVI_121446r 11325 essential YFL008W 2020 - TTCTTTATCCCACCTATTAT E|680|Q E|680|K SMC1 Stability of MiniChromosomes 1225.0 0 0 0 0 0.7207903457822575 P32908 0.956179976463318 0.9475290179252625 0.5089702010154724 0.6095154881477356 47.490705933015654 30.0 1.0 no 3653 chrVI_121638r 11326 essential YFL008W 2212 - CTCTAAACGATTTTCATCCA E|744|Q E|744|K SMC1 Stability of MiniChromosomes 1225.0 0 0 0 0 0.4438963820095057 P32908 0.956179976463318 0.9475290179252625 0.0 0.0 42.47052232945015 35.0 1.0 no 3654 chrVI_121700r 11328 essential YFL008W 2274 - TTCTTTAGTTCAGTTATCTT K|764|N silent|AAG>AAA|K|764 SMC1 Stability of MiniChromosomes 1225.0 0 0 0 0 -0.06263053361435908 P32908 0.9355990290641784 0.25105226039886475 42.481556977971756 25.0 1.0 no 3655 chrVI_130594 11338 essential YFL005W 260 + AGCGTATTATCGTGGTGCTA A|88|G A|88|V SEC4 SECretory 215.0 0 0 0 0 -1.8205281713968773 P07560 0.9484469890594482 0.9504740238189696 0.005885989870876074 0.007128816563636065 0.628898024559021 0.6235079765319824 0.6449999809265137 0.3858999907970429 0.8405334949493408 1.4497339725494385 50.53593436414047 45.0 1.0 no 3656 chrVI_145805r 11349 essential YFL002C 1107 + GCAATTACGTTTCTTAATGA A|370|G A|370|V SPB4 Suppressor of PAB1 606.0 0 0 0 0 0.015579651734697832 P25808 0.9117249846458436 0.9109519720077516 0.16027724742889404 0.01946118660271168 39.477421202660594 30.0 0.0 no 3657 chrVI_146016r 11354 essential YFL002C 896 + GCATGGAAAACTTCAAACAT H|300|D H|300|Y SPB4 Suppressor of PAB1 606.0 0 0 0 0 0.510433878090955 P25808 0.9914770126342772 0.9916279911994934 0.0 0.0 37.56298919764277 35.0 0.0 no 3658 chrVI_146082r 11356 essential YFL002C 830 + CTACTCATTTATCCAGTATT Y|278|* silent|TAC>TAT|Y|278 S|279|* S|279|L SPB4 Suppressor of PAB1 606.0 0 0 0 0 -0.8747410404656333 P25808 0.9589700102806092 0.4955281913280487 43.38628514675583 30.0 0.0 no 3659 chrVI_146212 11357 essential YFL002C 703 - ACAGTAATTTAATTTCAAAG C|241|S C|241|Y SPB4 Suppressor of PAB1 606.0 0 0 0 0 -0.3939730759491833 P25808 0.9687510132789612 0.95100998878479 0.1567947119474411 0.13412918150424954 30.41876580632362 20.0 0.0 no 3660 chrVI_146333 11362 essential YFL002C 582 - AGACCCGTCCTTCTTTGTTT G|200|A G|200|D G|200|R G|200|S SPB4 Suppressor of PAB1 606.0 0 0 0 0 0.6137284585834354 P25808 0.9557030200958252 0.9452409744262696 0.9398760199546814 0.9569429755210876 0.0 0.0 0.0 0.0 55.79955191274416 45.0 0.0 no 3661 chrVI_146421r 11363 essential YFL002C 491 + AGCATGCAGTATGGTAGTTA A|165|G A|165|V C|166|W silent|TGC>TGT|C|166 SPB4 Suppressor of PAB1 606.0 0 0 0 0 -0.018508505099333945 P25808 0.9764879941940308 0.9757149815559388 0.9499980211257936 0.134698286652565 0.07196886092424393 0.03737207502126694 48.22129962001219 40.0 0.0 no 3662 chrVI_146867 11374 essential YFL002C 48 - TCGAGTCCTGTCCTTATCCA D|23|H D|23|N G|21|A G|21|E SPB4 Suppressor of PAB1 606.0 0 0 0 0 -0.17782217517585688 P25808 0.965224027633667 0.97645902633667 0.9749379754066468 0.9595270156860352 0.1076887547969818 0.4105948507785797 1.0 0.031511764973402016 57.22024892221305 50.0 0.0 no 3663 chrVI_146873r 11375 essential YFL002C 39 + TTACTTCCCTGGATAAGGAC L|15|V L|15|F P|16|A P|16|S SPB4 Suppressor of PAB1 606.0 0 0 0 0 0.6846273892034854 P25808 0.9779649972915648 0.9867290258407592 0.9856799840927124 0.9771999716758728 0.5598936080932617 0.4800252914428711 0.1692408174276352 0.3783336579799652 47.54343036253067 45.0 0.0 no 3664 chrVI_146878r 11376 essential YFL002C 34 + TTTCTTTACTTCCCTGGATA S|13|C S|13|F SPB4 Suppressor of PAB1 606.0 0 0 0 0 0.4619147359449907 P25808 0.9720100164413452 0.9521960020065308 0.050416000187397 0.047498811036348336 48.686051956911 35.0 0.0 no 3665 chrVI_150112r 11380 essential YFR002W 99 - CCTAATTCAGAGGATGCTGA G|40|R G|40|S NIC96 Nucleoporin-Interacting Component of 96 kDa 839.0 0 0 0 0 -3.0720076877635627 P34077 0.0 0.0 46.95651990662799 45.0 1.0 yes 3666 chrVI_150112 11381 essential YFR002W 96 + CCATCAGCATCCTCTGAATT P|33|R P|33|L S|34|* S|34|L NIC96 Nucleoporin-Interacting Component of 96 kDa 839.0 0 0 0 0 -0.4400044027181508 P34077 0.0 0.0 0.27618253231048584 51.02394750777256 45.0 1.0 no 3667 chrVI_150213 11383 essential YFR002W 197 + TACTAAAGCCCACTATTTAT T|67|S T|67|I NIC96 Nucleoporin-Interacting Component of 96 kDa 839.0 0 0 0 0 0.9252659615283944 P34077 0.27838635444641113 0.01664821244776249 41.88261986111922 30.0 1.0 no 3668 chrVI_150438 11388 essential YFR002W 422 + TCATAACTTAAATCTTGATT H|142|D H|142|Y N|143|K silent|AAC>AAT|N|143 NIC96 Nucleoporin-Interacting Component of 96 kDa 839.0 0 0 0 0 0.5292862179544701 P34077 0.5746132731437683 0.07755564153194427 0.0 33.298899371803714 20.0 1.0 no 3669 chrVI_150562r 11392 essential YFR002W 549 - TTGCCCTTATTACCCCAGCT G|189|A G|189|D G|189|R G|189|S NIC96 Nucleoporin-Interacting Component of 96 kDa 839.0 0 0 0 0 -0.4659961301832943 P34077 0.7834556102752686 0.4396669864654541 0.5731167793273926 0.6702704429626465 60.11793780508282 50.0 1.0 no 3670 chrVI_150621 11393 essential YFR002W 605 + CAACGAAAATAATATCCTTA N|203|K silent|AAC>AAT|N|203 NIC96 Nucleoporin-Interacting Component of 96 kDa 839.0 0 1 0 0 0.06935987667219666 P34077 0.2814646363258362 0.7444000244140625 33.01462997054608 25.0 1.0 no 3671 chrVI_150682 11394 essential YFR002W 666 + AACAATAGTAGACAAGCAAA N|223|K silent|AAC>AAT|N|223 NIC96 Nucleoporin-Interacting Component of 96 kDa 839.0 0 0 0 0 -0.4849362175830802 P34077 0.0 9.166159629821776 33.844336329202015 30.0 1.0 no 3672 chrVI_150733 11395 essential YFR002W 717 + TCAATATTATCTTCTGCGAA S|240|* S|240|L NIC96 Nucleoporin-Interacting Component of 96 kDa 839.0 0 0 0 0 0.7274117662784769 P34077 0.10125018656253816 -1.1664999723434448 39.72831548463654 30.0 1.0 no 3673 chrVI_150982 11398 essential YFR002W 966 + TCTAATTTAACTGTTATCAA S|323|C S|323|F NIC96 Nucleoporin-Interacting Component of 96 kDa 839.0 0 0 0 0 0.6925193562204386 P34077 0.024850502610206604 0.01856746338307857 0.7092999815940857 0.6298199892044067 33.80863407074793 20.0 1.0 no 3674 chrVI_151298 11401 essential YFR002W 1282 + TTACTTTAAGCATTGAAGAT T|429|S T|429|I NIC96 Nucleoporin-Interacting Component of 96 kDa 839.0 0 0 0 0 -0.4306123389258039 P34077 0.4410865306854248 0.07431238889694214 0.8304200172424316 -2.0611600875854488 36.02595602559217 25.0 1.0 no 3675 chrVI_151450 11403 essential YFR002W 1434 + TTACAGACCCTTTTGTTAAG Q|480|E Q|480|* NIC96 Nucleoporin-Interacting Component of 96 kDa 839.0 0 0 0 0 1.0782997230426266 P34077 0.06408993154764175 2.020780086517334 43.478041466946365 35.0 1.0 no 3676 chrVI_151597r 11406 essential YFR002W 1584 - GCGAACCTGATATCCCTTTT A|535|P A|535|T R|533|S silent|AGG>AGA|R|533 NIC96 Nucleoporin-Interacting Component of 96 kDa 839.0 0 0 0 0 0.857338382804766 P34077 0.04203515127301216 0.05956390872597695 0.9561021327972412 -1.5670000314712524 1.065400004386902 -0.4095200002193451 51.29979191336354 45.0 1.0 no 3677 chrVI_151598r 11407 essential YFR002W 1585 - TGCGAACCTGATATCCCTTT A|535|P A|535|T R|533|S silent|AGG>AGA|R|533 NIC96 Nucleoporin-Interacting Component of 96 kDa 839.0 0 0 0 0 0.04036908570498271 P34077 0.04203515127301216 0.05956390872597695 0.9561021327972412 -1.5670000314712524 1.065400004386902 -0.4095200002193451 51.00517447182784 45.0 1.0 no 3678 chrVI_152877 11420 essential YFR003C 228 - TCTTCTTCATCCTCATTTTG E|83|Q E|83|K E|82|Q E|82|K 0 0 0 0 0.6381733646265084 P43587 0.93996000289917 0.9271510243415833 0.9423410296440125 0.9295319914817809 0.4583761394023895 0.6758403182029724 0.2645341753959656 0.3077675998210907 47.585519637063335 35.0 0.0 no 3679 chrVI_152967 11422 essential YFR003C 138 - CATCTTACATTGTGCCTTGT R|52|T R|52|K 0 0 0 0 0.3727531400561708 P43587 0.9260129928588868 0.9535790085792542 0.02091595716774464 0.12256046384572986 49.87659694944398 40.0 0.0 no 3680 chrVI_153049 11425 essential YFR003C 56 - CCTCTTCCACACTCACCGTT E|25|Q E|25|K E|25|D silent|GAG>GAA|E|25 0 1 0 0 0.3023167931210524 P43587 0.9439200162887572 0.9301249980926514 0.9338279962539672 0.2766284048557281 0.20217072963714602 0.2738856971263885 58.38859260689053 55.00000000000001 0.0 no 3681 chrVI_153050 11428 essential YFR003C 55 - CTCTTCCACACTCACCGTTC E|25|Q E|25|K E|24|Q E|24|K 0 1 0 0 0.540371259064047 P43587 0.9439200162887572 0.9301249980926514 0.9430189728736876 0.9292250275611876 0.2766284048557281 0.20217072963714602 0.5290790200233461 0.403312623500824 56.00117219846248 55.00000000000001 0.0 no 3682 chrVI_153445r 11433 essential YFR004W 55 - TTCTTTCGTATCGTCACGGC E|25|Q E|25|K silent|ACG>ACC|T|23 silent|ACG>ACA|T|23 RPN11 Regulatory Particle Non-ATPase 306.0 0 0 0 0 -1.2049105283907786 P43588 0.07719869166612625 0.007041207049041986 1.1253399848937988 1.5942399501800537 51.773120708875005 50.0 1.0 no 3683 chrVI_153528r 11436 essential YFR004W 138 - ATCAACCCCATGACTTCCAT L|52|F silent|TTG>TTA|L|52 silent|GGG>GGC|G|51 silent|GGG>GGA|G|51 RPN11 Regulatory Particle Non-ATPase 306.0 0 0 0 0 -1.1863586885679758 P43588 0.008698015473783016 -0.743399977684021 52.55627649623085 45.0 1.0 no 3684 chrVI_153529r 11437 essential YFR004W 139 - CATCAACCCCATGACTTCCA L|52|F silent|TTG>TTA|L|52 silent|GGG>GGC|G|51 silent|GGG>GGA|G|51 RPN11 Regulatory Particle Non-ATPase 306.0 0 0 0 0 -2.3080453367573184 P43588 0.008698015473783016 -0.743399977684021 53.70748590402769 50.0 1.0 yes 3685 chrVI_153653r 11439 essential YFR004W 263 - ACATGTCCATCATCTTCGCT M|94|I M|94|I D|93|H D|93|N RPN11 Regulatory Particle Non-ATPase 306.0 0 0 0 0 0.4067351949917485 P43588 0.03007692657411098 0.03007692657411098 0.0050150956958532325 0.013536946848034859 0.8138999938964844 0.8138999938964844 -0.0187199991196394 -0.392520010471344 3.1263000965118413 3.1263000965118413 52.868270576137384 45.0 1.0 no 3686 chrVI_153709 11441 essential YFR004W 316 + GCTGGTACCACTCTCATCCA silent|GGC>GGG|G|106 silent|GGC>GGT|G|106 RPN11 Regulatory Particle Non-ATPase 306.0 0 0 0 0 -0.2064707739252025 P43588 58.68357451511935 55.00000000000001 1.0 no 3687 chrVI_153815 11443 essential YFR004W 422 + TGACCCTATTCAATCCGTTA D|142|E silent|GAC>GAT|D|142 P|143|A P|143|S RPN11 Regulatory Particle Non-ATPase 306.0 0 0 0 0 -0.6748611013974711 P43588 0.0 0.017485901713371273 0.038363266736269 8.99888801574707 2.714060068130493 4.3282999992370605 48.884254149129454 40.0 1.0 no 3688 chrVI_153903 11447 essential YFR004W 510 + AGACAAACAACCTCCAACAC Q|172|E Q|172|* RPN11 Regulatory Particle Non-ATPase 306.0 0 0 0 0 0.3955271526028903 P43588 0.21642163395881653 42.627687957551025 45.0 1.0 no 3689 chrVI_153913r 11448 essential YFR004W 523 - GTTCAATAAGCCTGTGTTGG L|180|F silent|TTG>TTA|L|180 RPN11 Regulatory Particle Non-ATPase 306.0 0 0 0 0 -0.5066711383088047 P43588 0.024198586121201515 47.84457379757652 45.0 1.0 no 3690 chrVI_153917 11449 essential YFR004W 524 + CAACACAGGCTTATTGAACA N|176|K silent|AAC>AAT|N|176 T|177|R T|177|I RPN11 Regulatory Particle Non-ATPase 306.0 0 0 0 0 -1.343116108729165 P43588 0.04279380664229393 0.19133490324020386 0.7161875367164612 42.0078217496565 40.0 1.0 no 3691 chrVI_153942 11452 essential YFR004W 549 + AACATTCAAGCCTTAATTCA N|184|K silent|AAC>AAT|N|184 Q|186|E Q|186|* RPN11 Regulatory Particle Non-ATPase 306.0 0 0 0 0 0.8187034793877013 P43588 0.1876870095729828 0.9928894639015198 40.78982926032529 30.0 1.0 no 3692 chrVI_154009r 11453 essential YFR004W 619 - TAACATCTTGGTTTCCTTCG M|212|I M|212|I K|211|N silent|AAG>AAA|K|211 RPN11 Regulatory Particle Non-ATPase 306.0 0 0 0 0 -0.2707388975194209 P43588 0.14066839218139648 0.14066839218139648 0.4436317682266235 0.4951199889183045 0.4951199889183045 0.4360199868679047 1.2041000127792358 1.2041000127792358 0.3532800078392029 46.52563356906086 40.0 1.0 no 3693 chrVI_155087 11457 essential YFR005C 767 - TTACTTTGCCTTTACAAGAA V|262|L V|262|I SAD1 SnRNP Assembly Defective 448.0 0 0 0 0 -0.7396116496051078 P43589 0.9539830088615416 0.9574310183525084 0.04688622429966927 0.3663330972194672 -0.6525400280952454 0.24276000261306765 41.1057671834908 30.0 0.0 no 3694 chrVI_155202 11459 essential YFR005C 652 - ACCTTCTCTAACTTTCAAAT G|224|R G|224|S G|224|A G|224|D SAD1 SnRNP Assembly Defective 448.0 0 0 0 0 0.002979649174924437 P43589 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.3880517184734345 0.4474844634532929 0.5576548576354979 0.2487209737300873 2.5398199558258057 2.4962000846862797 2.646199941635132 2.438499927520752 41.242577543371 30.0 0.0 no 3695 chrVI_155203r 11460 essential YFR005C 648 + TCCTATTTGAAAGTTAGAGA silent|TCC>TCG|S|217 silent|TCC>TCT|S|217 S|217|C S|217|F SAD1 SnRNP Assembly Defective 448.0 0 0 0 0 0.3163976192369253 P43589 0.945252001285553 0.9294660091400146 0.05837089940905571 0.058373864740133286 0.093019999563694 -0.617900013923645 38.790075944926 30.0 0.0 no 3696 chrVI_155271 11461 essential YFR005C 583 - CCAAATTTTCTTTACACATA W|201|S W|201|* SAD1 SnRNP Assembly Defective 448.0 0 0 0 0 0.5141934210307126 P43589 0.8858469724655151 0.0 6.0381598472595215 38.178622284809705 25.0 0.0 no 3697 chrVI_155763 11468 essential YFR005C 91 - TCTTACTACAGTCTCAAGAT R|37|T R|37|K V|36|L V|36|I SAD1 SnRNP Assembly Defective 448.0 0 0 0 0 0.2717884234037778 P43589 0.932735025882721 0.955805003643036 0.9539830088615416 0.9574310183525084 0.34091365337371826 1.0 0.13395223021507266 0.08115432411432266 0.9585800170898438 0.06508000195026398 0.4277600049972534 -0.23837999999523166 42.50346594320922 35.0 0.0 no 3698 chrVI_186194 11471 high_effect YFR019W 53 + CAACAAAATGACACGGCAAA invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 0.6439427176603159 P34756 36.829863277534685 40.0 1.0 no 3699 chrVI_186299 11472 high_effect YFR019W 243 + AACATTCCCTCAAACGACAA invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 0.663738740058035 P34756 42.85225905673156 40.0 1.0 no 3700 chrVI_186477 11479 high_effect YFR019W 421 + ACAATCCAATTAGATCAATG invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 -0.19747213184831053 P34756 36.40172471985136 30.0 1.0 no 3701 chrVI_186952r 11487 high_effect YFR019W 899 - TACGCAAAGCGCCATCTAGA invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 -1.0015335597263335 P34756 49.09337672508605 50.0 1.0 no 3702 chrVI_187147r 11488 high_effect YFR019W 1094 - ACATGATTAATAGTATCCTT invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 -0.808545597807496 P34756 38.71755813350683 25.0 1.0 no 3703 chrVI_187218r 11490 high_effect YFR019W 1165 - TTCGCGCTCTTGCCTAAAGA invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 0.6850557281566828 P34756 51.608421249664275 50.0 1.0 no 3704 chrVI_187302r 11492 high_effect YFR019W 1249 - TAACGCGTACCCACTAACAT invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 0.3968990665501559 P34756 46.76487294553532 45.0 1.0 no 3705 chrVI_187809r 11497 high_effect YFR019W 1756 - TCTGGCTTTTTCCAATAAAA invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 0.12540854460480164 P34756 40.6849363511177 30.0 1.0 no 3706 chrVI_187931 11500 high_effect YFR019W 1875 + ACTATCACTAAGAAACACTT invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 0.3702263137150749 P34756 36.31741052834201 30.0 1.0 no 3707 chrVI_187969r 11502 high_effect YFR019W 1916 - TTTCAATTTCCATTTCATGC invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 -0.4615076789320907 P34756 43.62343265496679 30.0 1.0 no 3708 chrVI_188042 11504 high_effect YFR019W 1986 + TCATCATCACAGAACTTACT invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 0.059332084156991476 P34756 41.80294764465225 35.0 1.0 no 3709 chrVI_188137r 11506 high_effect YFR019W 2084 - AGTCAATAGTAACAATTTGA invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 -0.674510357000345 P34756 34.58448444710814 25.0 1.0 no 3710 chrVI_188225 11510 high_effect YFR019W 2169 + CCCTGCCAACAAGGCTGTAA invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 -0.5427199259531806 P34756 53.7668754827913 55.00000000000001 1.0 no 3711 chrVI_188225r 11511 high_effect YFR019W 2172 - CCATTACAGCCTTGTTGGCA invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 -0.3260824999543739 P34756 55.600669084707654 50.0 1.0 no 3712 chrVI_188230r 11513 high_effect YFR019W 2177 - ACAGACCATTACAGCCTTGT invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 -0.4348383834568042 P34756 51.50184423206014 45.0 1.0 no 3713 chrVI_188593r 11515 high_effect YFR019W 2540 - TCCATTTTATTTTGCGTGGT invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 0.8742956328502298 P34756 48.74568784831212 35.0 1.0 no 3714 chrVI_188620 11517 high_effect YFR019W 2564 + TCATATCGACATCAAACTGA invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 0.6473976443125399 P34756 39.19686622166864 35.0 1.0 no 3715 chrVI_188623 11518 high_effect YFR019W 2567 + TATCGACATCAAACTGAAGG invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 0.9016467607735752 P34756 38.08292565838253 40.0 1.0 no 3716 chrVI_189068r 11522 high_effect YFR019W 3015 - AACGGTAATTCGTTCTTTTC invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 -0.2065332373171757 P34756 42.098125304475325 35.0 1.0 no 3717 chrVI_189086r 11523 high_effect YFR019W 3033 - ACATCTTTCAATCCCTCTAA invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 0.7797692837864466 P34756 46.272684702717235 35.0 1.0 no 3718 chrVI_189302r 11528 high_effect YFR019W 3249 - GTTCCACTTCTGCTTATTGG invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 -0.6890809149153592 P34756 51.70618685579933 45.0 1.0 no 3719 chrVI_189305r 11529 high_effect YFR019W 3252 - CCTGTTCCACTTCTGCTTAT invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 -1.0530830841105812 P34756 54.67225669330156 45.0 1.0 no 3720 chrVI_189484r 11532 high_effect YFR019W 3431 - CCAGTTCAAATTCTTTCGAC invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 0.1778402281002992 P34756 43.94839009496633 40.0 1.0 no 3721 chrVI_189562 11533 high_effect YFR019W 3506 + ACAAACATCCACACCAATTG invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 0.4602162702238005 P34756 42.222622576100996 40.0 1.0 no 3722 chrVI_189658 11536 high_effect YFR019W 3602 + TGCGAATGTTAAGACTTTGG invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 -0.3412498386373984 P34756 41.1222971998871 40.0 1.0 no 3723 chrVI_189722r 11540 high_effect YFR019W 3669 - TCCAAGTTTTGATCTAAATT invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 0.1619205858165183 P34756 38.02661910724697 25.0 1.0 no 3724 chrVI_189769r 11541 high_effect YFR019W 3716 - TCAAAATGTTTTCTCCCCAT invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 -0.1672765690059703 P34756 46.750681761523936 35.0 1.0 no 3725 chrVI_189922 11545 high_effect YFR019W 3866 + AACAACAACAACTGTCAATA invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 0.7117313686179858 P34756 34.53976866220262 30.0 1.0 no 3726 chrVI_190287 11552 high_effect YFR019W 4231 + CAACTTCTCATAATAAGGGG invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 0.39774646477480186 P34756 39.91541494932847 40.0 1.0 no 3727 chrVI_190288 11553 high_effect YFR019W 4232 + AACTTCTCATAATAAGGGGA invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 -0.3375681363072829 P34756 39.76586562892085 35.0 1.0 no 3728 chrVI_190335r 11554 high_effect YFR019W 4282 - GTTCAACAAGCCCTCTTTGG invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 -0.5585102379171545 P34756 51.881089780044526 50.0 1.0 no 3729 chrVI_190365r 11558 high_effect YFR019W 4312 - CCTATCTCGGGCGCCTTCAA invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 -1.797831866785701 P34756 58.40483617400679 60.0 1.0 no 3730 chrVI_190389r 11561 high_effect YFR019W 4336 - ATGCGTTTGTGATTCTTGTG invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 -0.11086682080772864 P34756 46.78955116903933 40.0 1.0 no 3731 chrVI_190617r 11564 high_effect YFR019W 4564 - GCTCCCACTTTTCCCCCCAT invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 0.3945984949069623 P34756 67.66415091078721 60.0 1.0 no 3732 chrVI_190720 11565 high_effect YFR019W 4664 + ACCAAGTTATTTTGAATACA invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 0.9727646811784424 P34756 37.5378906109064 25.0 1.0 no 3733 chrVI_190756 11566 high_effect YFR019W 4700 + CCATGATTTGCCCACGACTT invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 -0.034812593971022106 P34756 53.34483077070405 50.0 1.0 no 3734 chrVI_190770 11569 high_effect YFR019W 4714 + CGACTTTGGCTAAAGTATTT invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 -0.5364673461800618 P34756 41.392334407532026 35.0 1.0 no 3735 chrVI_190830r 11570 high_effect YFR019W 4777 - AACGTCCATTTTATAACTTT invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 0.5298165502386838 P34756 39.277506643129975 25.0 1.0 no 3736 chrVI_191000r 11571 high_effect YFR019W 4947 - TCATATTCGCGAACATGAAT invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 -2.0026061485967444 P34756 39.935666842018925 35.0 1.0 no 3737 chrVI_191149 11574 high_effect YFR019W 5093 + TTTCATTCGAACGTTTACAT invalid seq invalid seq invalid seq invalid seq FAB1 Forms Aploid and Binucleate cells 2278.0 0 0 0 0 -0.09078683375470437 P34756 40.34155363033312 30.0 1.0 no 3738 chrVI_207777r 11587 essential YFR027W 328 - TACAATCTTCTCCTCCTGAT V|116|L V|116|I K|114|N silent|AAG>AAA|K|114 0 0 0 0 -4.320911619148844 P43605 0.15791331231594086 0.17658139765262604 0.22129881381988525 49.337517711822564 40.0 1.0 yes 3739 chrVI_207778r 11588 essential YFR027W 329 - ATACAATCTTCTCCTCCTGA V|116|L V|116|I 0 0 0 0 0.7757257242358486 P43605 0.15791331231594086 0.17658139765262604 49.337517711822436 40.0 1.0 no 3740 chrVI_207809r 11589 essential YFR027W 360 - ACTTCACCATTCGACTTATC V|127|L V|127|I E|126|Q E|126|K 0 0 0 0 -0.3091189472835334 P43605 0.05716006830334664 0.5649522542953491 0.08156271278858185 0.09911254048347473 46.2887838651153 40.0 1.0 no 3741 chrVI_208009 11593 essential YFR027W 557 + ATCTAGTCGTGGACGTTGGA S|187|C S|187|F 0 0 0 0 1.101461365357162 P43605 0.08532612770795822 0.06983169913291931 50.59520260699765 50.0 1.0 no 3742 chrVI_208819 11595 essential YFR028C 1230 - CTTCCATTATTCGCCGTAGA G|416|A G|416|E G|416|R G|416|R CDC14 Cell Division Cycle 551.0 0 1 0 0 -0.0006705504670175833 Q00684 0.9499930143356324 0.9438679814338684 0.941340982913971 0.941340982913971 0.5999167561531067 0.7359066009521484 0.2989349961280823 0.2989349961280823 51.309203330700655 45.0 0.0 no 3743 chrVI_208870r 11600 essential YFR028C 1176 + ACGCCGCCATCCAACGGTCA P|394|A P|394|S T|393|R T|393|M CDC14 Cell Division Cycle 551.0 0 1 0 0 0.1682278684908479 Q00684 0.9562489986419678 0.9498909711837769 0.9476869702339172 0.9502379894256592 0.05515379458665848 0.0631345584988594 0.017051294445991516 0.009076008573174477 59.723580149580755 65.0 0.0 no 3744 chrVI_209051 11605 essential YFR028C 998 - TCCATTCTCTAAAATCATTC W|339|S W|339|* W|339|C W|339|* CDC14 Cell Division Cycle 551.0 0 0 0 0 -2.7790889597762085 Q00684 0.8858469724655151 0.8858469724655151 0.002413482405245304 0.0017549627227708695 39.676674882476284 30.0 0.0 yes 3745 chrVI_209113r 11607 essential YFR028C 933 + TTCTTAAGGTTTATAAGGCC F|312|L silent|TTC>TTT|F|312 CDC14 Cell Division Cycle 551.0 0 0 0 0 0.07794676842294446 Q00684 0.9387490153312684 0.036962833255529404 43.27990659916816 35.0 0.0 no 3746 chrVI_209327r 11613 essential YFR028C 719 + AGACATTGGCATTCAACATT D|241|E silent|GAC>GAT|D|241 CDC14 Cell Division Cycle 551.0 0 0 0 0 0.8922982001638562 Q00684 0.9532920122146606 0.7953358888626099 42.933495447380274 35.0 0.0 no 3747 chrVI_209390r 11614 essential YFR028C 656 + CAACAATAACGTCCAATTAG N|220|K silent|AAC>AAT|N|220 CDC14 Cell Division Cycle 551.0 0 0 0 0 0.3924989736943227 Q00684 0.9439849853515624 0.7094820141792297 36.784943887176276 35.0 0.0 no 3748 chrVI_209465 11617 essential YFR028C 584 - TAGCGAGATAGCCCTTTGGA A|201|P A|201|T CDC14 Cell Division Cycle 551.0 0 0 0 0 0.39871754854125335 Q00684 0.9573720097541808 0.9523990154266356 0.2711799740791321 0.5253656506538391 4.691999912261963 -0.08380000293254852 52.69193447033001 50.0 0.0 no 3749 chrVI_209476r 11619 essential YFR028C 570 + CCACAAGAGGACCATCCAAA Q|192|E Q|192|* P|191|R P|191|L CDC14 Cell Division Cycle 551.0 0 0 0 0 -0.2977119491615317 Q00684 0.9590039849281312 0.9432820081710817 0.9430609941482544 0.2897695004940033 0.0 0.0 0.14579999446868894 47.867593640692924 50.0 0.0 no 3750 chrVI_209565 11624 essential YFR028C 484 - CTCGTAACTCTCCAAATTGA E|168|Q E|168|K CDC14 Cell Division Cycle 551.0 0 0 0 0 1.2694941416387406 Q00684 0.956179976463318 0.9475290179252625 0.0 0.0 43.40600888905425 40.0 0.0 no 3751 chrVI_209680 11628 essential YFR028C 369 - GCATCTCTAAATGGCATGAA A|130|P A|130|T D|129|H D|129|N CDC14 Cell Division Cycle 551.0 0 0 0 0 -4.093032075986471 Q00684 0.9573720097541808 0.9523990154266356 0.9486550092697144 0.956179976463318 0.0 0.0 0.0 0.0 1.0626000165939329 0.4603999853134155 43.274154844483746 40.0 0.0 yes 3752 chrVI_209830 11635 essential YFR028C 219 - ACGGCTTTATTGGCATTTTC V|80|L V|80|I A|79|P A|79|T CDC14 Cell Division Cycle 551.0 0 0 0 0 -0.3142613497503189 Q00684 0.9539830088615416 0.9574310183525084 0.9573720097541808 0.9523990154266356 0.08176262676715851 0.8054884672164917 0.3365956246852875 0.4307826161384583 -1.9206000566482544 2.8926000595092773 48.14809733394504 40.0 0.0 no 3753 chrVI_227912 11640 essential YFR037C 1255 - GCTTTCTTCAATGTACTTTT S|425|T S|425|N E|424|Q E|424|K RSC8 Remodel the Structure of Chromatin 557.0 0 0 0 0 -0.05613337832406279 P43609 0.4005758762359619 0.32102397084236145 0.33949485421180725 0.04817383736371994 44.032125459985075 30.0 0.0 no 3754 chrVI_228081r 11645 essential YFR037C 1083 + AACTACATCCGAGAAGTTGT N|362|K silent|AAC>AAT|N|362 Y|363|* silent|TAC>TAT|Y|363 RSC8 Remodel the Structure of Chromatin 557.0 0 0 0 0 0.5298174580437107 P43609 1.0 43.58669382742739 40.0 0.0 no 3755 chrVI_228106r 11647 essential YFR037C 1058 + ATTCCTAAGCTTACCGATCG F|354|L silent|TTC>TTT|F|354 L|355|V silent|CTA>TTA|L|355 RSC8 Remodel the Structure of Chromatin 557.0 0 0 0 0 -0.2193204649603358 P43609 0.02336189709603786 0.060147039592266076 47.96992255735426 45.0 0.0 no 3756 chrVI_228318r 11651 essential YFR037C 846 + TGCTCCCGTTGTTTCCAAGA C|283|W silent|TGC>TGT|C|283 S|284|C S|284|F RSC8 Remodel the Structure of Chromatin 557.0 0 0 0 0 -1.2819021964343276 P43609 0.0015311792958527806 0.057019706815481186 0.13207581639289856 56.024110728344 50.0 0.0 no 3757 chrVI_228319r 11652 essential YFR037C 845 + GTGCTCCCGTTGTTTCCAAG C|283|W silent|TGC>TGT|C|283 S|284|C S|284|F RSC8 Remodel the Structure of Chromatin 557.0 0 0 0 0 -0.6053194967367921 P43609 0.0015311792958527806 0.057019706815481186 0.13207581639289856 57.569515784447276 55.00000000000001 0.0 no 3758 chrVI_228352r 11655 essential YFR037C 812 + CTACCACAATTTGCGTGCAC Y|272|* silent|TAC>TAT|Y|272 H|273|D H|273|Y RSC8 Remodel the Structure of Chromatin 557.0 0 0 0 0 0.4233861326930416 P43609 0.027425460517406464 0.032919153571128845 49.368062989538366 50.0 0.0 no 3759 chrVI_228570 11659 essential YFR037C 597 - ATCACATTCTCTGGTAAAAA silent|GTG>GTC|V|205 silent|GTG>GTA|V|205 V|205|L V|205|M RSC8 Remodel the Structure of Chromatin 557.0 0 0 0 0 -0.8080573126082526 P43609 0.5089083313941956 0.1564870923757553 37.66318710279523 30.0 0.0 no 3760 chrVI_228561 11660 essential YFR037C 606 - TCTTGCTTGATCACATTCTC E|209|Q E|209|K K|207|N silent|AAG>AAA|K|207 RSC8 Remodel the Structure of Chromatin 557.0 0 0 0 0 -1.2131878205426871 P43609 0.06561505049467088 0.481746256351471 0.43195411562919617 47.545280001697385 40.0 0.0 no 3761 chrVI_228610 11663 essential YFR037C 557 - TGTCCAGAACCACTTGGAAG D|192|H D|192|N silent|CTG>CTC|L|191 silent|CTG>CTA|L|191 RSC8 Remodel the Structure of Chromatin 557.0 0 0 0 0 -4.646622008828039 P43609 0.0 0.0 47.77652514110548 50.0 0.0 yes 3762 chrVI_228725 11671 essential YFR037C 442 - CACTATCGAGGCAACATCCA V|154|L V|154|M silent|TCG>TCC|S|152 silent|TCG>TCA|S|152 RSC8 Remodel the Structure of Chromatin 557.0 0 0 0 0 -5.941802989707928 P43609 0.7044115662574768 0.2590889632701874 49.205832849509314 50.0 0.0 yes 3763 chrVI_228746 11672 essential YFR037C 421 - GGCAACATTTCTTCTCACAG A|147|P A|147|T V|146|L V|146|I RSC8 Remodel the Structure of Chromatin 557.0 0 0 0 0 -0.5380661636220673 P43609 0.017442263662815094 0.012315294705331327 0.9183602929115297 1.0 47.42501333201 45.0 0.0 no 3764 chrVI_228854r 11673 essential YFR037C 310 + ACTTTTTCAACGATTCATCA D|104|E silent|GAC>GAT|D|104 RSC8 Remodel the Structure of Chromatin 557.0 0 0 0 0 0.4921619178861441 P43609 0.8641849756240845 41.09972648753592 30.0 0.0 no 3765 chrVI_228930 11676 essential YFR037C 237 - GCAAACGACGGAATAATCAC A|86|P A|86|T silent|TCG>TCC|S|84 silent|TCG>TCA|S|84 RSC8 Remodel the Structure of Chromatin 557.0 0 0 0 0 -6.0861508390959775 P43609 0.0178061593323946 0.017947178333997726 39.326461790170185 45.0 0.0 yes 3766 chrVI_229031 11679 essential YFR037C 136 - AGCTACTTCTGCTCCCAATG A|52|P A|52|T V|51|L V|51|I RSC8 Remodel the Structure of Chromatin 557.0 0 0 0 0 -1.3506552162748906 P43609 0.1533299833536148 0.316905289888382 0.342837393283844 0.5147745609283447 53.478180175763605 50.0 0.0 no 3767 chrVI_229068 11681 essential YFR037C 99 - GCCTGTTCCTGTGCTAAGTG Q|39|H silent|CAG>CAA|Q|39 A|40|P A|40|T RSC8 Remodel the Structure of Chromatin 557.0 0 0 0 0 -0.8557040746747341 P43609 0.08744940161705017 57.02190374155714 55.00000000000001 0.0 no 3768 chrVI_229069 11682 essential YFR037C 98 - CCTGTTCCTGTGCTAAGTGA Q|39|H silent|CAG>CAA|Q|39 E|38|Q E|38|K RSC8 Remodel the Structure of Chromatin 557.0 0 0 0 0 -4.909869922746584 P43609 0.08744940161705017 0.34667015075683594 0.3577057421207428 54.34536282616125 50.0 0.0 yes 3769 chrVI_229075r 11684 essential YFR037C 89 + ATCTTTCCCTCACTTAGCAC S|31|C S|31|F F|32|L silent|TTC>TTT|F|32 RSC8 Remodel the Structure of Chromatin 557.0 0 0 0 0 0.2502750782512498 P43609 0.07734139263629912 0.10038086771965027 0.8003718256950378 53.17566381303027 45.0 0.0 no 3770 chrVI_238522 11692 essential YFR042W 64 + ATGCTGCATTATTGATACGG A|23|G A|23|V A|24|G A|24|V 0 0 0 0 -1.5440062968388502 P43614 0.2278652191162109 0.6146948337554932 0.11210758984088898 0.07615939527750015 44.33767767479111 40.0 1.0 no 3771 chrVI_238624r 11693 essential YFR042W 169 - CCAAATAACTTCCATGATGC W|63|S W|63|* 0 0 0 0 0.26008463591159603 P43614 0.012951243668794632 42.92902046987905 40.0 1.0 no 3772 chrVI_238658r 11695 essential YFR042W 203 - GCAAACCATATTTGAACCCG L|74|F silent|TTG>TTA|L|74 G|73|A G|73|D 0 0 0 0 0.1608678442763415 P43614 0.127689391374588 0.7059063911437988 0.6763108968734741 45.588024283969844 45.0 1.0 no 3773 chrVI_238832 11697 essential YFR042W 374 + GTGCAAACTTTTTAAACGTA C|126|W silent|TGC>TGT|C|126 0 0 0 0 1.2219642686161178 P43614 0.18506281077861786 37.59927334076292 30.0 1.0 no 3774 chrVI_238810 11698 essential YFR042W 352 + TATCACAGGCATATTGCCAT S|119|* S|119|L Q|120|E Q|120|* 0 0 0 0 -5.152317283691209 P43614 0.11931757628917695 0.8830617666244507 48.647716422888486 40.0 1.0 yes 3775 chrVI_238833 11699 essential YFR042W 375 + TGCAAACTTTTTAAACGTAA C|126|W silent|TGC>TGT|C|126 L|128|V L|128|F 0 0 0 0 0.3514631272937655 P43614 0.18506281077861786 0.4934845566749573 0.2950226664543152 34.31226768766209 25.0 1.0 no 3776 chrVI_249289 11701 essential YFR050C 558 - TCTACAACTTTCCTTAACAG D|193|H D|193|N V|192|L V|192|I PRE4 PRoteinase yscE 266.0 0 1 0 0 -0.7933169938092551 P30657 0.030711382627487183 0.055703550577163696 0.8993121385574341 0.7407285571098328 1.3211599588394165 -0.16646000742912292 41.21030400832257 35.0 0.0 no 3777 chrVI_249341r 11707 essential YFR050C 503 + TACGTATTCGTCTCCCACCT T|169|R T|169|M PRE4 PRoteinase yscE 266.0 0 0 0 0 0.2968954615668463 P30657 0.00670250505208969 0.005125979892909528 55.814436030987 50.0 0.0 no 3778 chrVI_249524r 11711 essential YFR050C 320 + TGCGTATGACAATCCTCTAG A|108|G A|108|V PRE4 PRoteinase yscE 266.0 0 0 0 0 -0.04137411675322236 P30657 0.40600162744522095 0.5607224106788635 0.36010000109672546 0.243479996919632 46.43078004927679 45.0 0.0 no 3779 chrVI_249600 11713 essential YFR050C 247 - ATCACCTGAAATGCCCACAA D|89|H D|89|N G|88|A G|88|D PRE4 PRoteinase yscE 266.0 0 0 0 0 -1.1692147859711588 P30657 0.002440214389935136 0.006548712961375713 0.0 0.0 48.21968377685977 45.0 0.0 no 3780 chrVI_249615 11714 essential YFR050C 232 - CACAACGGTGTTATCACCCA V|84|L V|84|M V|83|L V|83|I PRE4 PRoteinase yscE 266.0 0 0 0 0 -1.9537396627881904 P30657 0.3827895224094391 0.01048324815928936 0.21296793222427368 0.305588036775589 50.9127651897761 50.0 0.0 no 3781 chrVI_249745r 11721 essential YFR050C 99 + ACACAGCAACCAATAGTAAC Q|35|E Q|35|* T|34|R T|34|I PRE4 PRoteinase yscE 266.0 0 0 0 0 -1.9601058941848448 P30657 0.5022034049034119 0.005151889752596618 0.006921679712831974 -0.2666400074958801 -0.02617999911308289 0.18476000428199768 40.96406910521876 40.0 0.0 no 3782 chrVI_250591r 11731 essential YFR051C 1190 + TCCATTAACTCTAACTACAT P|398|R P|398|L P|398|A P|398|S RET2 RETrieval from ER 546.0 0 0 0 0 -1.0662607973694649 P43621 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 7.046396732330322 1.3443640470504759 2.989451169967652 4.068583011627196 40.14619922972753 30.0 0.0 no 3783 chrVI_250651 11733 essential YFR051C 1133 - ATCTTAGAACACCCAGGCTT R|384|T R|384|K RET2 RETrieval from ER 546.0 0 0 0 0 0.8009663065374713 P43621 0.932735025882721 0.955805003643036 0.0 0.0 0.9195640087127686 -0.11931999772787096 50.7989291649426 45.0 0.0 no 3784 chrVI_250662 11734 essential YFR051C 1122 - CCCAGGCTTTGGTCGTTGGC silent|CTG>CTC|L|380 silent|CTG>CTA|L|380 G|381|R G|381|S RET2 RETrieval from ER 546.0 0 0 0 0 0.313764547462357 P43621 0.941340982913971 0.951104998588562 0.0 0.0 -0.3521159887313843 0.04123599827289581 62.8294002902536 65.0 0.0 no 3785 chrVI_250662r 11736 essential YFR051C 1119 + CCAGCCAACGACCAAAGCCT P|374|R P|374|L A|375|G A|375|V RET2 RETrieval from ER 546.0 0 0 0 0 -0.1865435776405797 P43621 0.9432820081710817 0.9430609941482544 0.9484469890594482 0.9504740238189696 0.0 0.0 0.25774678587913513 0.11539586633443832 1.7340480089187622 1.2415180206298828 0.8718500137329102 2.262432336807251 54.84337507591374 60.0 0.0 no 3786 chrVI_250687 11739 essential YFR051C 1097 - AAGCCTTAGATTTATCACGC A|372|P A|372|T K|371|N silent|AAG>AAA|K|371 RET2 RETrieval from ER 546.0 0 0 0 0 -0.2024434626894518 P43621 0.9573720097541808 0.9523990154266356 0.9355990290641784 0.6277408003807068 0.4392361640930176 0.0149356871843338 0.7927860021591187 0.18124599754810333 0.8282060027122498 45.62359072004678 40.0 0.0 no 3787 chrVI_250926 11743 essential YFR051C 858 - ATCAAAATACCATTGTTCTC L|292|F silent|TTG>TTA|L|292 RET2 RETrieval from ER 546.0 0 0 0 0 0.5177834824291132 P43621 0.9587849974632264 0.2771008610725403 3.0619170665740967 38.96377211282055 30.0 0.0 no 3788 chrVI_250927 11744 essential YFR051C 857 - TCAAAATACCATTGTTCTCT L|292|F silent|TTG>TTA|L|292 RET2 RETrieval from ER 546.0 0 0 0 0 -1.3339189669536144 P43621 0.9587849974632264 0.2771008610725403 3.0619170665740967 40.73821038700055 30.0 0.0 no 3789 chrVI_250941 11745 essential YFR051C 843 - TTCTCTGGGACATCCTCCTC E|287|D silent|GAG>GAA|E|287 E|287|Q E|287|K RET2 RETrieval from ER 546.0 0 0 0 0 -0.9700287442733 P43621 0.94931298494339 0.956179976463318 0.9475290179252625 0.4728682935237885 0.37022504210472107 0.5057580471038818 0.8587999939918518 0.9054780006408693 1.1999119520187378 57.946240739572495 55.00000000000001 0.0 no 3790 chrVI_250960r 11747 essential YFR051C 821 + TTCTGGCACTCCACCTCCTC S|275|C S|275|F silent|GGC>GGG|G|276 silent|GGC>GGT|G|276 RET2 RETrieval from ER 546.0 0 1 0 0 0.3635402396859207 P43621 0.945252001285553 0.9294660091400146 0.08392807096242905 0.1107845976948738 62.343781809742616 60.0 0.0 no 3791 chrVI_250957r 11748 essential YFR051C 824 + TGGCACTCCACCTCCTCCGG silent|GGC>GGG|G|276 silent|GGC>GGT|G|276 T|277|S T|277|I RET2 RETrieval from ER 546.0 0 0 1 Series([], Name: modification, dtype: object) 0 0.07039230318292139 P43621 0.9491789937019348 0.9472420215606691 0.6437598466873169 0.5212635993957521 65.09057731567407 70.0 0.0 no 3792 chrVI_251279r 11764 essential YFR051C 502 + TTGCTAGAAAAGAACATGAA A|169|G A|169|V RET2 RETrieval from ER 546.0 0 0 0 0 0.004533903092102998 P43621 0.9484469890594482 0.9504740238189696 0.16067779064178467 0.1177557185292244 33.473857083865084 30.0 0.0 no 3793 chrVI_251293 11765 essential YFR051C 491 - TTCTAGCAATTTCCTTAGCA R|170|T R|170|K A|169|P A|169|T RET2 RETrieval from ER 546.0 0 0 0 0 0.4768878516859121 P43621 0.932735025882721 0.955805003643036 0.9573720097541808 0.9523990154266356 0.20310933887958527 0.5684750080108643 0.14375518262386322 0.22881728410720825 47.22938356980194 35.0 0.0 no 3794 chrVI_251365r 11766 essential YFR051C 416 + GTCGCACGAAGAAAGAATCC S|140|W S|140|L H|141|D H|141|Y RET2 RETrieval from ER 546.0 0 0 0 0 -2.596449633549234 P43621 0.9288619756698608 0.9298099875450134 0.9473130106925964 0.9489949941635132 0.0 0.0 0.0 0.0 43.25434864690965 50.0 0.0 yes 3795 chrVI_251563 11775 essential YFR051C 221 - AATCCTTGATAATATTGGAC D|80|H D|80|N K|79|N silent|AAG>AAA|K|79 RET2 RETrieval from ER 546.0 0 0 0 0 0.8406868761515316 P43621 0.9486550092697144 0.956179976463318 0.9355990290641784 0.0 0.0 0.022800184786319733 37.78271041863832 30.0 0.0 no 3796 chrVI_251566 11776 essential YFR051C 218 - CCTTGATAATATTGGACTGG K|79|N silent|AAG>AAA|K|79 RET2 RETrieval from ER 546.0 0 0 0 0 0.2221163833775412 P43621 0.9355990290641784 0.022800184786319733 42.32902664572259 40.0 0.0 no 3797 chrVI_251566r 11777 essential YFR051C 215 + CCGCCAGTCCAATATTATCA silent|CGC>CGG|R|73 silent|CGC>CGT|R|73 R|73|G R|73|C RET2 RETrieval from ER 546.0 0 0 0 0 0.06400351375660834 P43621 0.8994590044021606 0.8926740288734436 0.01903427578508854 0.0025628884322941303 51.31627126800197 45.0 0.0 no 3798 chrVI_251765r 11783 essential YFR051C 16 + CTTCTATCACTACGCGTCAG S|7|C S|7|F RET2 RETrieval from ER 546.0 0 1 0 0 0.5508193870567838 P43621 0.945252001285553 0.9294660091400146 0.0 0.0 49.01452538448183 50.0 0.0 no 3799 chrVI_251766r 11784 essential YFR051C 15 + GCTTCTATCACTACGCGTCA A|6|G A|6|V S|7|C S|7|F RET2 RETrieval from ER 546.0 0 1 0 0 0.008366633594533102 P43621 0.9484469890594482 0.9504740238189696 0.945252001285553 0.9294660091400146 0.046223994344472885 0.015855157747864727 0.0 0.0 52.654079320256024 50.0 0.0 no 3800 chrVI_253044r 11797 essential YFR052W 542 - CGTCTCTTATAGCTGATTTT D|187|H D|187|N R|186|T R|186|K RPN12 Regulatory Particle Non-ATPase 274.0 0 0 0 0 -1.4175233872354225 P32496 0.20220993459224698 0.6383810043334961 0.0 0.0 45.28154284744085 35.0 1.0 no 3801 chrVI_253101 11798 essential YFR052W 596 + TCTCCCTCTCTCCAACATAA silent|CTC>CTG|L|200 silent|CTC>CTT|L|200 L|200|V L|200|F RPN12 Regulatory Particle Non-ATPase 274.0 0 0 0 0 0.8381724924243815 P32496 0.05057509243488312 0.030898652970790863 3.208440065383911 1.3891600370407104 2.053400039672852 -0.20280000567436215 52.30688532229175 45.0 1.0 no 3802 chrVII_36981r 11803 essential YGL247W 51 - ACTTCCTCCCTTCCCAATCT V|24|L V|24|I E|23|Q E|23|K 0 0 0 0 0.18733457044672872 P53062 0.9539830088615416 0.9574310183525084 0.956179976463318 0.9475290179252625 0.4576464891433716 0.3150721788406372 59.98900769356817 50.0 1.0 no 3803 chrVII_37040r 11804 essential YGL247W 110 - GGCTCAACCAAATGCTTTGT S|43|T S|43|N L|42|F silent|TTG>TTA|L|42 0 0 0 0 -0.2185310003439432 P53062 0.9512869715690612 0.9536849856376648 0.9587849974632264 0.2941974401473999 0.7202744483947754 0.6960787773132324 48.746905166722854 45.0 1.0 no 3804 chrVII_37241 11807 essential YGL247W 308 + CCAGTGCGAACCTCATATGA Q|104|E Q|104|* C|105|W silent|TGC>TGT|C|105 0 0 0 0 -4.568667000124812 P53062 0.9590039849281312 0.9286419749259948 1.0 0.0 50.21377083129482 50.0 1.0 yes 3805 chrVII_37266r 11810 essential YGL247W 336 - TTGCAACGTACCTCCAATGC C|118|S C|118|Y R|117|P R|117|H 0 0 0 0 -1.7767823115778183 P53062 0.9421560168266296 0.9290120005607604 0.9099509716033936 0.9570810198783876 0.0 0.0 0.19600747525691986 0.14522257447242734 50.4730248026895 50.0 1.0 no 3806 chrVII_37330r 11813 essential YGL247W 400 - TGCTTTAGCCCATTGGTAAT A|140|P A|140|T 0 0 0 0 -1.0146332556150994 P53062 0.9573720097541808 0.9523990154266356 0.017688257619738582 0.037860631942749016 50.399339623875726 40.0 1.0 no 3807 chrVII_37337r 11815 essential YGL247W 407 - GAGCCCATGCTTTAGCCCAT A|142|P A|142|T W|141|C W|141|* 0 0 0 0 0.5406666940264305 P53062 0.9573720097541808 0.9523990154266356 0.8858469724655151 0.02145935222506523 0.13069356977939606 0.0 60.81721734018504 55.00000000000001 1.0 no 3808 chrVII_37910 11817 high_effect YGL246C 851 - CCACAGTTTTTAATACATAA V|290|L V|290|M silent|GTG>GTC|V|290 silent|GTG>GTA|V|290 RAI1 Rat1p Interacting Protein 387.0 0 0 0 0 -0.2082485754881217 P53063 0.05123422294855118 0.009787758812308313 -1.4479999542236328 -3.0176000595092773 37.146652256753036 25.0 0.0 no 3809 chrVII_37965r 11818 high_effect YGL246C 793 + GGCTGCAATGCTTCTTAGTT L|266|V silent|CTG>TTG|L|266 Q|267|E Q|267|* RAI1 Rat1p Interacting Protein 387.0 0 0 0 0 -0.4479084643695849 P53063 0.4475422501564026 0.0 52.00786965366268 45.0 0.0 no 3810 chrVII_38040 11824 high_effect YGL246C 721 - TTGCTGCGTACATTTCAATT Q|246|H silent|CAG>CAA|Q|246 silent|ACG>ACC|T|245 silent|ACG>ACA|T|245 RAI1 Rat1p Interacting Protein 387.0 0 1 0 0 -0.3827742696160069 P53063 0.07495982199907303 0.25040000677108765 45.099255419700796 35.0 0.0 no 3811 chrVII_38152r 11825 high_effect YGL246C 606 + TACATTAGTGTTGTGAGAAC Y|203|* silent|TAC>TAT|Y|203 RAI1 Rat1p Interacting Protein 387.0 0 1 0 0 0.8044917121848911 P53063 39.1530871781103 35.0 0.0 no 3812 chrVII_38313r 11828 high_effect YGL246C 445 + CTTCCTCTGCAACTGAAGCA S|150|C S|150|F silent|TCC>TCG|S|150 silent|TCC>TCT|S|150 RAI1 Rat1p Interacting Protein 387.0 0 0 0 0 -0.05685253036261876 P53063 0.0644225925207138 0.0979674756526947 0.6723999977111816 0.07199999690055847 51.071874093201984 50.0 0.0 no 3813 chrVII_38464r 11830 high_effect YGL246C 294 + GCTGATATAATTACTTTTAG A|99|G A|99|V RAI1 Rat1p Interacting Protein 387.0 0 0 0 0 0.4103337231099585 P53063 0.35576575994491577 0.3547297418117523 1.0944000482559204 1.5324000120162964 35.440117041153485 25.0 0.0 no 3814 chrVII_39054r 11834 essential YGL245W 34 - TTCAGCATAAGCCACAATTG E|18|Q E|18|K A|17|P A|17|T GUS1 GlUtamyl-tRNA Synthetase 708.0 0 0 0 0 -0.11668647201216813 P46655 0.956179976463318 0.9475290179252625 0.9573720097541808 0.9523990154266356 0.20611228048801425 0.3054042756557465 0.3414202332496643 0.19855310022830966 1.9740400314331052 2.2426199913024902 -1.12090003490448 1.4082599878311155 44.10944322553735 40.0 1.0 no 3815 chrVII_39110r 11836 essential YGL245W 90 - AACTTAATAGCTATGGAGTT K|36|N silent|AAG>AAA|K|36 GUS1 GlUtamyl-tRNA Synthetase 708.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.7139751819003727 P46655 0.9355990290641784 0.4349744915962219 0.7672399878501892 38.97553206335692 30.0 1.0 no 3816 chrVII_39112 11837 essential YGL245W 89 + TAACTCCATAGCTATTAAGT N|31|K silent|AAC>AAT|N|31 S|32|C S|32|F GUS1 GlUtamyl-tRNA Synthetase 708.0 0 0 0 0 -0.7358689999648078 P46655 0.9439849853515624 0.945252001285553 0.9294660091400146 0.8902847170829773 0.02735196985304356 0.03725527226924896 -0.005840000230818987 0.13198000192642212 -0.6419199705123901 40.73873941130249 30.0 1.0 no 3817 chrVII_39213r 11841 essential YGL245W 193 - ATCACCATTATCGAAGATGG D|71|H D|71|N G|70|A G|70|D GUS1 GlUtamyl-tRNA Synthetase 708.0 0 1 0 0 0.2508003699168788 P46655 0.9486550092697144 0.956179976463318 0.9499930143356324 0.9446240067481996 0.06667739897966385 0.3721957802772522 0.8801811933517456 0.6115935444831848 4.895520210266113 3.21072006225586 3.5952401161193848 6.678160190582275 42.499594331434366 40.0 1.0 no 3818 chrVII_39295 11842 essential YGL245W 272 + TGCTAAATTATCACAATCAT A|92|G A|92|V GUS1 GlUtamyl-tRNA Synthetase 708.0 0 1 0 0 0.0745715609248297 P46655 0.9484469890594482 0.9504740238189696 0.2102913558483124 0.17426881194114685 0.4898000061511994 0.22935999929904935 0.5898000001907349 0.2773999869823456 36.05044356336305 25.0 1.0 no 3819 chrVII_39429r 11846 essential YGL245W 409 - ATCAACCTTGTTCTTGATGA D|143|H D|143|N V|142|L V|142|I GUS1 GlUtamyl-tRNA Synthetase 708.0 0 0 0 0 0.7392529579732526 P46655 0.9486550092697144 0.956179976463318 0.9539830088615416 0.9574310183525084 0.5514221787452698 0.3026154637336731 0.40838077664375305 0.2462611496448517 -1.67385995388031 -1.5849000215530396 -1.0609200000762942 0.4745799899101257 -1.6757800579071045 -0.1881600022315979 44.613348908052 35.0 1.0 no 3820 chrVII_39605r 11849 essential YGL245W 585 - ACTTCACCCATTTTGGCATC V|202|L V|202|I E|201|Q E|201|K GUS1 GlUtamyl-tRNA Synthetase 708.0 0 0 0 0 0.6246294079478208 P46655 0.9539830088615416 0.9574310183525084 0.956179976463318 0.9475290179252625 0.035960789769887924 0.12934435904026031 0.6583436131477356 1.0 52.66301603777346 45.0 1.0 no 3821 chrVII_39778r 11851 essential YGL245W 758 - AATCTTCCAAAATAGAGTCT D|259|H D|259|N E|258|Q E|258|K GUS1 GlUtamyl-tRNA Synthetase 708.0 0 0 0 0 -1.0627053665424502 P46655 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.0 0.0 0.053647056221961975 0.19844402372837067 38.592757741656214 30.0 1.0 no 3822 chrVII_39853r 11853 essential YGL245W 833 - CACAGTAGTCGTACATTTCT C|284|S C|284|Y GUS1 GlUtamyl-tRNA Synthetase 708.0 0 0 0 0 -0.5129948220398186 P46655 0.9421560168266296 0.9290120005607604 0.20512032508850095 0.011807343922555448 46.285503492860975 40.0 1.0 no 3823 chrVII_39917r 11854 essential YGL245W 897 - TCTTCTCTCATCTTTTCAGT E|306|Q E|306|K E|305|Q E|305|K GUS1 GlUtamyl-tRNA Synthetase 708.0 0 1 0 0 -0.7185820439676409 P46655 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.3965027034282684 0.03969869017601013 0.4600175619125366 0.6821891665458679 49.3310798886916 35.0 1.0 no 3824 chrVII_40181r 11860 essential YGL245W 1161 - CCTTCAATAGCATCAACAAT G|394|R G|394|S E|393|Q E|393|K GUS1 GlUtamyl-tRNA Synthetase 708.0 0 0 0 0 0.7899764134548818 P46655 0.941340982913971 0.951104998588562 0.956179976463318 0.9475290179252625 0.0 0.0 0.05415290594100952 0.007631430868059397 41.586851299514535 35.0 1.0 no 3825 chrVII_40240r 11863 essential YGL245W 1220 - TCCAATCATATTGAGCGTTA W|413|S W|413|* W|413|C W|413|* GUS1 GlUtamyl-tRNA Synthetase 708.0 0 0 0 0 -0.06389037564011385 P46655 0.8858469724655151 0.8858469724655151 0.0 0.0 44.225084548925906 35.0 1.0 no 3826 chrVII_40329r 11865 essential YGL245W 1309 - TAACTTTCTCTTAGACAACA K|442|N silent|AAG>AAA|K|442 GUS1 GlUtamyl-tRNA Synthetase 708.0 0 0 0 0 0.6572752167802719 P46655 0.9355990290641784 0.0 38.50986141095871 30.0 1.0 no 3827 chrVII_40403r 11869 essential YGL245W 1383 - CTTCTCACACCCCTGACAGT R|467|T R|467|K silent|GTG>GTC|V|466 silent|GTG>GTA|V|466 GUS1 GlUtamyl-tRNA Synthetase 708.0 0 0 0 0 0.5118856201798818 P46655 0.932735025882721 0.955805003643036 0.14193999767303467 0.598480761051178 57.55095996392663 55.00000000000001 1.0 no 3828 chrVII_40510 11875 essential YGL245W 1487 + GATCTGGGCTTTCAACAAGA I|497|M silent|ATC>ATT|I|497 GUS1 GlUtamyl-tRNA Synthetase 708.0 0 0 0 0 0.07318224422119078 P46655 0.9598389863967896 0.06573515385389328 46.2969731119241 45.0 1.0 no 3829 chrVII_48819 11888 high_effect YGL240W 206 + CCACCAAGGTATTGAAATAT H|70|Q silent|CAC>CAT|H|70 H|70|D H|70|Y 0 0 0 0 -0.3969445345009003 P53068 0.9588389992713928 0.9473130106925964 0.9489949941635132 0.3259668052196503 0.2397011965513229 1.0 -0.8391799926757812 0.3199400007724762 -0.5346199870109558 41.076614578792096 35.0 1.0 no 3830 chrVII_48805 11889 high_effect YGL240W 192 + TTGCAACATATGTTCCACCA Q|66|E Q|66|* H|67|D H|67|Y 0 0 0 0 0.06689793571870872 P53068 0.9590039849281312 0.9473130106925964 0.9489949941635132 1.0 0.6255343556404114 0.10439740121364594 -0.13053999841213226 0.1770000010728836 -0.5255399942398071 48.49898472887594 40.0 1.0 no 3831 chrVII_48819r 11890 high_effect YGL240W 209 - CCAATATTTCAATACCTTGG L|76|F silent|TTG>TTA|L|76 0 0 0 0 0.24068889760547185 P53068 0.9587849974632264 0.030453331768512726 1.5672199726104736 41.991053666661 35.0 1.0 no 3832 chrVII_48822r 11891 high_effect YGL240W 212 - AATCCAATATTTCAATACCT D|77|H D|77|N L|76|F silent|TTG>TTA|L|76 0 0 0 0 0.4434475652637648 P53068 0.9486550092697144 0.956179976463318 0.9587849974632264 0.057682499289512634 0.3828352093696594 0.030453331768512726 0.7649199962615967 -0.010080000385642052 1.5672199726104736 39.039799852864924 25.0 1.0 no 3833 chrVII_48883 11892 high_effect YGL240W 270 + AAGCCTTCTTCTTTTAAGTT P|92|A P|92|S P|92|R P|92|L 0 0 0 0 0.455892268304921 P53068 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.8180829286575317 0.11756063997745515 0.020197581499814987 0.02873406745493412 2.078439950942993 3.6142199039459233 3.694040060043335 3.819580078125 44.76721424686725 30.0 1.0 no 3834 chrVII_49060r 11898 high_effect YGL240W 450 - GCGTAAACTTTCACTAAGCT A|157|P A|157|T 0 0 0 0 0.2226868395045424 P53068 0.9573720097541808 0.9523990154266356 0.181610643863678 0.3448235392570496 0.6956200003623962 0.10760000348091124 5.003119945526123 2.201940059661865 43.86968758888411 40.0 1.0 no 3835 chrVII_49709r 11908 essential YGL238W 160 - GAACAAAGCACCTGCTAATC L|59|F silent|TTG>TTA|L|59 CSE1 Chromosome SEgregation 960.0 0 0 0 0 -1.7141330717683831 P33307 0.9587849974632264 0.017360346391797066 43.24075332548648 45.0 1.0 no 3836 chrVII_49892 11912 essential YGL238W 340 + ACTCTGATTTTCCTGATAGG S|115|C S|115|F D|114|E silent|GAC>GAT|D|114 CSE1 Chromosome SEgregation 960.0 0 0 0 0 0.6622490817907829 P33307 0.945252001285553 0.9294660091400146 0.9532920122146606 0.004120042081922293 0.002486618235707283 0.3118763864040375 -0.20919999480247495 -0.3052000105381012 -0.878000020980835 46.08715337639791 40.0 1.0 no 3837 chrVII_49915r 11913 essential YGL238W 366 - GCTAAATCACTCAAAAGTGT A|129|P A|129|T CSE1 Chromosome SEgregation 960.0 0 0 0 0 -2.3573132235836134 P33307 0.9573720097541808 0.9523990154266356 0.015355031937360762 0.1301884949207306 38.73404642651428 35.0 1.0 yes 3838 chrVII_49991 11914 essential YGL238W 439 + CACATTCTATTTTTAAAAGA H|148|D H|148|Y S|149|C S|149|F CSE1 Chromosome SEgregation 960.0 0 0 0 0 0.2784694080642884 P33307 0.9473130106925964 0.9489949941635132 0.945252001285553 0.9294660091400146 0.0 0.0 0.004956910386681557 0.0020752563141286373 32.54387759394307 20.0 1.0 no 3839 chrVII_50271 11915 essential YGL238W 719 + GTCATATTCTAATCCTTTAT S|241|* S|241|L CSE1 Chromosome SEgregation 960.0 0 0 0 0 -0.2729739735628379 P33307 0.9298099875450134 0.6465292572975159 40.93381314687258 25.0 1.0 no 3840 chrVII_50374 11919 essential YGL238W 822 + ACAAGATATGAAGATGTCTT T|275|R T|275|I CSE1 Chromosome SEgregation 960.0 0 0 0 0 0.8004213434486037 P33307 0.9476869702339172 0.9472420215606691 0.16674567759037018 0.5989402532577515 0.4584000110626221 -1.5335999727249146 36.72564480238203 30.0 1.0 no 3841 chrVII_50672r 11923 essential YGL238W 1123 - ACATGCCCTTCTTCTAGTGT C|381|S C|381|Y A|380|P A|380|T CSE1 Chromosome SEgregation 960.0 0 0 0 0 -1.014138172749142 P33307 0.9421560168266296 0.9290120005607604 0.9573720097541808 0.9523990154266356 0.1618245095014572 0.005387514363974333 0.03655927255749703 0.030474567785859108 55.49611238793625 45.0 1.0 no 3842 chrVII_50798r 11924 essential YGL238W 1249 - ATCTTTAAATTTCCAATTTT D|423|H D|423|N CSE1 Chromosome SEgregation 960.0 0 0 0 0 0.5180395126848479 P33307 0.9486550092697144 0.956179976463318 0.0 0.0 35.23730333231117 15.0 1.0 no 3843 chrVII_50837 11926 essential YGL238W 1285 + TCACTGCATTGGCCATTAAT T|430|S T|430|I F|429|L silent|TTC>TTT|F|429 CSE1 Chromosome SEgregation 960.0 0 0 0 0 -0.06290615224041332 P33307 0.9491789937019348 0.9472420215606691 0.9387490153312684 1.0 0.09002344310283661 0.03853344544768333 48.28939397088647 40.0 1.0 no 3844 chrVII_50885r 11927 essential YGL238W 1336 - AACATTTAGTAAGTTGTTTG V|452|L V|452|I CSE1 Chromosome SEgregation 960.0 0 0 0 0 0.6522136117078062 P33307 0.9539830088615416 0.9574310183525084 0.048763468861579895 0.7211437821388245 35.524171072551496 25.0 1.0 no 3845 chrVII_51147 11929 essential YGL238W 1595 + TCCTGCTTTTATTTTTCATA P|533|R P|533|L P|533|A P|533|S CSE1 Chromosome SEgregation 960.0 0 0 0 0 0.24762587352127724 P33307 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.6195902228355408 0.7297733426094055 0.8294561505317688 0.8435764908790588 0.7020000219345093 0.8163999915122986 1.0808000564575195 0.27079999446868896 44.33666350138424 25.0 1.0 no 3846 chrVII_51241r 11930 essential YGL238W 1692 - TCGTTTTCAGCTAGTTTTTC E|571|Q E|571|K CSE1 Chromosome SEgregation 960.0 0 0 0 0 0.33881272200268553 P33307 0.956179976463318 0.9475290179252625 0.016709715127944946 0.013015303760766985 46.86420359531081 35.0 1.0 no 3847 chrVII_51576 11933 essential YGL238W 2024 + TCCAGAAAGTATCAAGCCGT P|676|R P|676|L P|676|A P|676|S CSE1 Chromosome SEgregation 960.0 0 0 0 0 0.6370674432817303 P33307 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.02234358713030815 0.1363517940044403 0.16404113173484802 0.27120938897132874 47.549091788332255 45.0 1.0 no 3848 chrVII_51616r 11937 essential YGL238W 2067 - CCTTTCAATTCCCATACATT G|696|R G|696|S L|694|F silent|TTG>TTA|L|694 CSE1 Chromosome SEgregation 960.0 0 0 0 0 0.2266309023355901 P33307 0.941340982913971 0.951104998588562 0.9587849974632264 0.0 0.0 0.707373321056366 47.73290976399079 35.0 1.0 no 3849 chrVII_51700 11940 essential YGL238W 2148 + CCCGATCTAGTCCCTGTTTT silent|CCC>CCG|P|717 silent|CCC>CCT|P|717 P|717|R P|717|L CSE1 Chromosome SEgregation 960.0 0 0 0 0 -0.3985531487004774 P33307 0.9432820081710817 0.9430609941482544 0.5150896310806274 0.31450480222702026 57.78923165145858 50.0 1.0 no 3850 chrVII_59136r 11942 essential YGL233W 17 - AATCTTTTGAAAGCAATGGC D|12|H D|12|N SEC15 SECretory 910.0 0 0 0 0 0.7557787468461951 P22224 39.2891705701856 35.0 1.0 no 3851 chrVII_59186r 11945 essential YGL233W 67 - TGTCCACGATGAATTGTTTC W|28|C W|28|* W|28|S W|28|* SEC15 SECretory 910.0 0 0 0 0 -0.4001553669232065 P22224 44.729202152652086 40.0 1.0 no 3852 chrVII_59257r 11947 essential YGL233W 138 - ACATCATTTTGGCCCAGCGC V|53|L V|53|M D|52|H D|52|N SEC15 SECretory 910.0 0 0 0 0 0.16225708654199952 P22224 0.4128913283348084 0.12434238195419313 0.025965841487050056 0.05958907306194305 57.26531963999207 55.00000000000001 1.0 no 3853 chrVII_59355r 11950 essential YGL233W 236 - TTTCCAATTCATCAATTACG E|85|Q E|85|K L|84|F silent|TTG>TTA|L|84 SEC15 SECretory 910.0 0 0 0 0 -0.1253270967372674 P22224 0.5162651538848877 0.5810301303863525 0.0 39.41642355652061 30.0 1.0 no 3854 chrVII_59380 11951 essential YGL233W 258 + TCAATTGAGGATAACTTTCA S|87|* S|87|L SEC15 SECretory 910.0 0 0 0 0 -1.9254379878684151 P22224 0.21746599674224854 38.204622863838274 30.0 1.0 no 3855 chrVII_59461 11952 essential YGL233W 339 + GACGAAATTGCAAACATCCA D|114|E silent|GAC>GAT|D|114 SEC15 SECretory 910.0 0 0 0 0 1.39528290584493 P22224 0.9753590822219848 40.90413592531586 40.0 1.0 no 3856 chrVII_59613 11953 essential YGL233W 491 + AGCAACAATTTTAATCACTA A|165|G A|165|V T|166|R T|166|I SEC15 SECretory 910.0 0 0 0 0 0.3621744805902599 P22224 0.08528818935155869 0.08622188121080399 0.1882358342409134 0.3135809898376465 36.071410917021524 25.0 1.0 no 3857 chrVII_59657r 11955 essential YGL233W 538 - GATCAATTCTTGACATTTGC L|185|F silent|TTG>TTA|L|185 SEC15 SECretory 910.0 0 0 0 0 -0.3612520033420368 P22224 0.06272691488265991 41.60640343981999 35.0 1.0 no 3858 chrVII_59694 11956 essential YGL233W 572 + TTTCAAAGTTTTACAAAACT F|192|L silent|TTC>TTT|F|192 SEC15 SECretory 910.0 0 0 0 0 0.8301528019059268 P22224 0.06574530899524689 32.15305730854578 20.0 1.0 no 3859 chrVII_60146 11961 essential YGL233W 1024 + AACTAATGTATCCATTGATA L|343|V silent|CTA>TTA|L|343 SEC15 SECretory 910.0 0 0 0 0 1.2932658573177565 P22224 0.8213552832603455 37.165917912858895 25.0 1.0 no 3860 chrVII_60599r 11966 essential YGL233W 1480 - TTCATCGTCAAAAGCTCTCA E|500|Q E|500|K D|499|H D|499|N SEC15 SECretory 910.0 0 0 0 0 1.0736270268090302 P22224 0.32421737909317017 0.041084032505750656 0.12824460864067078 0.4941394031047821 44.87796627408829 40.0 1.0 no 3861 chrVII_77124r 11976 essential YGL225W 233 - CGTCTGTTTTGTTTAATGAA D|84|H D|84|N VRG4 Vandate Resistance Glycosylation 337.0 0 0 0 0 -0.3882607083336379 P40107 0.965224027633667 0.97645902633667 0.2101875990629196 0.30653977394104004 39.761704663535056 30.0 1.0 no 3862 chrVII_77199 11978 essential YGL225W 305 + TTCGAAGGCTTTACAATACT S|103|W S|103|L VRG4 Vandate Resistance Glycosylation 337.0 0 0 0 0 -0.1515028426086864 P40107 0.9416270256042479 0.9508730173110962 0.0024137008003890514 0.08566990494728087 41.38004748749489 35.0 1.0 no 3863 chrVII_77343 11982 essential YGL225W 449 + TTCTTCTGTCGTTGCAACTT S|151|C S|151|F S|152|C S|152|F VRG4 Vandate Resistance Glycosylation 337.0 0 0 0 0 0.09452402484865302 P40107 0.9720100164413452 0.9521960020065308 0.9720100164413452 0.9521960020065308 0.0 0.0 0.0049881129525601855 0.0019236161606386304 49.02350429306949 40.0 1.0 no 3864 chrVII_77370r 11985 essential YGL225W 479 - CCTTGGCAGCCACAGCTTGC K|166|N silent|AAG>AAA|K|166 A|165|P A|165|T VRG4 Vandate Resistance Glycosylation 337.0 0 0 0 0 -0.0814148171371907 P40107 0.94167298078537 0.9600390195846558 0.9535790085792542 0.4997361898422241 0.29837796092033386 0.6277987957000732 62.68550798566474 65.0 1.0 no 3865 chrVII_77387r 11987 essential YGL225W 496 - TTCAGCCAATGAAGCAGCCT E|172|Q E|172|K A|171|P A|171|T VRG4 Vandate Resistance Glycosylation 337.0 0 0 0 0 0.012403615330955577 P40107 0.9656620025634766 0.953271985054016 0.9690340161323548 0.960402011871338 0.585207998752594 0.9084485769271852 0.3014585375785828 0.5765781402587891 52.942339625985774 50.0 1.0 no 3866 chrVII_77422 11988 essential YGL225W 528 + GCTGTTGCCTCCTTTAACCC A|177|G A|177|V VRG4 Vandate Resistance Glycosylation 337.0 0 0 0 0 0.875641498045288 P40107 0.9542440176010132 0.95346999168396 0.3799796998500824 0.2985609471797943 59.7300591065835 55.00000000000001 1.0 no 3867 chrVII_77585 11991 essential YGL225W 691 + TTTCTTTCTGTGTGGAAGAT S|232|C S|232|F VRG4 Vandate Resistance Glycosylation 337.0 0 0 0 0 0.4579341408199544 P40107 0.9634199738502502 0.9436050057411194 0.0032980197574943304 0.0019611031748354435 44.233601565030476 35.0 1.0 no 3868 chrVII_81779r 11996 no_effect YGL221C 491 + ATTCAATAAAGACATCTCTT F|165|L silent|TTC>TTT|F|165 NIF3 Ngg1p-Interacting Factor 288.0 0 0 0 0 1.0651295046852225 P53081 1.0 -2.6884000301361084 35.6991665407682 25.0 0.0 no 3869 chrVII_81837 11999 no_effect YGL221C 436 - TTCGCCACTTACAGTTTCCA E|152|Q E|152|K G|151|A G|151|D NIF3 Ngg1p-Interacting Factor 288.0 0 0 0 0 0.4952974508868711 P53081 0.3635675609111786 0.5129000544548035 0.8284159898757935 0.6237164735794067 53.45755022407235 45.0 0.0 no 3870 chrVII_81909 12004 no_effect YGL221C 364 - GTCATTTACACCGCCACGAG D|128|H D|128|N NIF3 Ngg1p-Interacting Factor 288.0 0 0 0 0 0.3703550033714743 P53081 0.0 0.0 52.479777158362815 55.00000000000001 0.0 no 3871 chrVII_82016 12012 no_effect YGL221C 257 - GGCTTAATCTGTTCCAGCTT S|92|T S|92|N NIF3 Ngg1p-Interacting Factor 288.0 0 0 0 0 0.17866528281631885 P53081 1.0 0.20553657412528992 53.21706726295224 45.0 0.0 no 3872 chrVII_82208 12017 no_effect YGL221C 65 - TCTTGTCTGCGTACTTTTGA K|28|N silent|AAG>AAA|K|28 D|27|H D|27|N NIF3 Ngg1p-Interacting Factor 288.0 0 0 0 0 0.3357413584641429 P53081 0.16128087043762207 0.00421639159321785 0.01156067941337824 48.95126206662548 40.0 0.0 no 3873 chrVII_99027r 12020 essential YGL207W 61 - ACCTTCAAACTCATTGTACT G|27|R G|27|S G|27|A G|27|D SPT16 SuPpressor of Ty 1035.0 0 0 0 0 0.4569285307799251 P32558 0.8749529719352722 0.9426419734954834 0.9376609921455384 0.8936529755592346 0.42491865158081055 0.6925805807113647 0.7242363691329956 0.9421668052673341 1.3968000411987305 2.6184000968933105 1.968000054359436 2.1480000019073486 43.90606004875668 35.0 1.0 no 3874 chrVII_99155 12023 essential YGL207W 186 + ACTTTGATTGCATTAGTTCC T|63|S T|63|I SPT16 SuPpressor of Ty 1035.0 0 0 0 0 0.4949696110705684 P32558 0.8074929714202881 0.614982008934021 0.0 0.0 1.2319999933242798 1.6275999546051023 45.87292879231239 35.0 1.0 no 3875 chrVII_99248r 12025 essential YGL207W 282 - TCCAGCGTAATTTTGCTTTC silent|CTG>CTC|L|100 silent|CTG>CTA|L|100 E|101|Q E|101|K SPT16 SuPpressor of Ty 1035.0 0 0 0 0 0.21454884553939507 P32558 0.9157350063323976 0.9241359829902648 0.06795598566532135 0.07309195399284363 -0.06840000301599503 -0.2667999863624573 48.544761651641295 40.0 1.0 no 3876 chrVII_99385r 12028 essential YGL207W 419 - ACTCAGTCATAAATTTACCT E|146|Q E|146|K E|146|D silent|GAG>GAA|E|146 SPT16 SuPpressor of Ty 1035.0 0 0 0 0 0.0691724524068919 P32558 0.9281650185585022 0.8806899785995483 0.9648290276527404 0.02206735499203205 0.01717875897884369 0.2373295277357101 0.7343999743461609 1.4736000299453735 1.2300000190734863 41.14965339164815 30.0 1.0 no 3877 chrVII_99412r 12032 essential YGL207W 446 - TCACAGCCGCTTCCCATACT V|155|L V|155|M silent|GTG>GTC|V|155 silent|GTG>GTA|V|155 SPT16 SuPpressor of Ty 1035.0 0 0 0 0 -0.08060050446368207 P32558 0.9796169996261596 0.9505040049552916 0.3193404674530029 0.10945937037467957 0.6552000045776367 -0.39660000801086426 0.5614799857139587 -0.799019992351532 58.92040334011829 55.00000000000001 1.0 no 3878 chrVII_99413r 12033 essential YGL207W 447 - TTCACAGCCGCTTCCCATAC silent|GTG>GTC|V|155 silent|GTG>GTA|V|155 V|155|L V|155|M SPT16 SuPpressor of Ty 1035.0 0 0 0 0 -0.27202522475934743 P32558 0.9796169996261596 0.9505040049552916 0.3193404674530029 0.10945937037467957 0.6552000045776367 -0.39660000801086426 0.5614799857139587 -0.799019992351532 57.46318901855295 55.00000000000001 1.0 no 3879 chrVII_99514 12035 essential YGL207W 545 + CTTCCTGTCCGTTTCAAGTA F|183|L silent|TTC>TTT|F|183 L|184|V silent|CTG>TTG|L|184 SPT16 SuPpressor of Ty 1035.0 0 0 0 0 -0.1820169778529672 P32558 0.9089890122413636 0.8861060142517091 0.7586609721183777 0.786726176738739 2.1440000534057617 1.4573999643325806 52.58311815234907 45.0 1.0 no 3880 chrVII_99674r 12039 essential YGL207W 708 - GGGCATAATGCGCTTAAATC C|242|S C|242|Y SPT16 SuPpressor of Ty 1035.0 0 0 0 0 0.13706638676983368 P32558 0.8891630172729492 0.8145110011100769 0.5856496095657349 1.0 1.0413999557495115 7.078199863433838 0.3608199954032898 7.49560022354126 44.87107221935344 45.0 1.0 no 3881 chrVII_99786r 12041 essential YGL207W 820 - CAACTGATCATTGGTAGAAC Q|279|H silent|CAG>CAA|Q|279 SPT16 SuPpressor of Ty 1035.0 0 0 0 0 -0.052136516546700866 P32558 0.9861209988594056 0.12108584493398665 1.7319999933242798 39.67364136481297 40.0 1.0 no 3882 chrVII_99791 12043 essential YGL207W 822 + TCTACCAATGATCAGTTGTA S|275|C S|275|F T|276|S T|276|I SPT16 SuPpressor of Ty 1035.0 0 0 0 0 -1.6423133179679164 P32558 0.6862930059432983 0.6474459767341614 0.9300180077552797 0.8602150082588196 0.0070920973084867 0.0036764573305845256 0.2893942594528198 0.023583484813570976 2.0190000534057617 3.9916000366210938 -0.2755999863147736 0.9154000282287598 43.841129783391246 35.0 1.0 no 3883 chrVII_99968r 12046 essential YGL207W 1002 - ACTTCTTTTGGTGTACGGCC V|341|L V|341|I E|340|Q E|340|K SPT16 SuPpressor of Ty 1035.0 0 0 0 0 -3.6795036911766834 P32558 0.8715159893035889 0.9354289770126344 0.9369189739227296 0.926666021347046 0.5162827372550964 0.660828173160553 0.07386855036020279 0.2896982431411743 0.4424000084400177 -0.4465999901294708 0.6672000288963318 1.448799967765808 54.04982444545397 50.0 1.0 yes 3884 chrVII_100040 12048 essential YGL207W 1071 + CCCAATTTCACCAAAAACAT silent|CCC>CCG|P|358 silent|CCC>CCT|P|358 P|358|R P|358|L SPT16 SuPpressor of Ty 1035.0 0 0 0 0 -0.17566281406607287 P32558 0.9856510162353516 0.9573950171470642 0.4804352521896362 0.2761113941669464 0.9990000128746032 1.3411999940872192 41.36637083320039 35.0 1.0 no 3885 chrVII_100050r 12049 essential YGL207W 1084 - AATCAATGAACCAATGTTTT L|367|F silent|TTG>TTA|L|367 SPT16 SuPpressor of Ty 1035.0 0 0 0 0 0.7132524571207386 P32558 0.6192139983177185 0.43792957067489613 1.35099995136261 1.521939992904663 36.28543953958024 25.0 1.0 no 3886 chrVII_100204 12051 essential YGL207W 1235 + CGCTTTACAATTAGCTGATA A|413|G A|413|V SPT16 SuPpressor of Ty 1035.0 0 0 0 0 0.24552708479870394 P32558 0.8463379740715027 0.8165500164031982 0.17672692239284515 0.19611628353595734 1.7050000429153442 4.514599800109863 1.6979999542236328 3.5552399158477783 42.10787462032886 35.0 1.0 no 3887 chrVII_100356r 12053 essential YGL207W 1390 - GTCTGGTTTACTAGGGACTT D|470|H D|470|N SPT16 SuPpressor of Ty 1035.0 0 0 0 0 -0.3675463710809233 P32558 0.9766839742660522 1.0189900398254397 0.11879414319992065 0.4827535152435303 50.24915991203318 45.0 1.0 no 3888 chrVII_100419r 12056 essential YGL207W 1453 - AGCGTCTTCGGCACCACCAC A|491|P A|491|T D|490|H D|490|N SPT16 SuPpressor of Ty 1035.0 0 1 0 0 -2.019939941495432 P32558 0.9719979763031006 1.0155500173568726 0.9716339707374572 1.0184899568557741 0.2341925352811813 0.5441467761993408 0.01238267868757248 0.20377370715141296 60.305998382507255 65.0 1.0 yes 3889 chrVII_100649 12058 essential YGL207W 1680 + ACAATTATTCTACCCATTTA T|561|R T|561|I SPT16 SuPpressor of Ty 1035.0 0 0 0 0 0.8651667652158258 P32558 0.7930759787559509 0.8146799802780151 0.005109355319291353 0.005785528104752302 41.208818170428856 25.0 1.0 no 3890 chrVII_100744 12059 essential YGL207W 1775 + ACGTTTGAACTTTAATTCAC R|593|G R|593|C SPT16 SuPpressor of Ty 1035.0 0 0 0 0 0.7649745855431054 P32558 0.8077729940414429 0.8070939779281616 0.0 0.0 1.6418000459671018 0.6277999877929688 37.62230584866506 30.0 1.0 no 3891 chrVII_100857r 12060 essential YGL207W 1891 - ACTCATGCGGTCACCATCTT M|636|I M|636|I S|637|T S|637|N SPT16 SuPpressor of Ty 1035.0 0 0 0 0 -1.457781388005169 P32558 1.0259499549865725 1.0259499549865725 1.0138800144195557 1.0207300186157229 0.41025510430336 0.41025510430336 0.6210615038871765 0.5336380004882812 1.5861999988555908 1.5861999988555908 54.628049647723124 50.0 1.0 no 3892 chrVII_101082 12066 essential YGL207W 2113 + TCAGATTTCAATCCCCACTA I|705|M silent|ATC>ATT|I|705 SPT16 SuPpressor of Ty 1035.0 0 0 0 0 0.02748895050816589 P32558 0.9521149992942809 0.026377787813544273 0.38321998715400696 49.50201296333017 40.0 1.0 no 3893 chrVII_101095r 12068 essential YGL207W 2129 - TTCTGCTATCAGTCCTTAGT R|716|T R|716|K S|715|T S|715|N SPT16 SuPpressor of Ty 1035.0 0 0 0 0 -0.6265771695208636 P32558 0.9461849927902222 1.0183099508285522 0.9054579734802246 0.9503009915351868 0.047151453793048866 1.0 0.21249260008335116 0.2889586091041565 0.3287000060081482 -0.11630000174045566 -0.6424000263214111 -1.334820032119751 51.80256530500896 40.0 1.0 no 3894 chrVII_101207r 12070 essential YGL207W 2241 - TTCTTTTTACCCATTAAAAT K|753|N silent|AAG>AAA|K|753 SPT16 SuPpressor of Ty 1035.0 0 0 0 0 0.348078188670588 P32558 0.8356549739837646 0.010890320874750614 0.6948999762535095 37.86088306006803 20.0 1.0 no 3895 chrVII_118975r 12081 essential YGL201C 1910 + TATCGATGAATTTGATAAAA I|638|M silent|ATC>ATT|I|638 MCM6 MiniChromosome Maintenance 1017.0 0 0 0 0 0.3377133079082729 P53091 0.8604419827461243 0.0 30.210488553548323 20.0 0.0 no 3896 chrVII_119074r 12082 essential YGL201C 1811 + GGCTGCTGGTTTAACAGCTG A|605|G A|605|V A|606|G A|606|V MCM6 MiniChromosome Maintenance 1017.0 0 0 0 0 -0.9916280822313688 P53091 0.9497479796409608 0.8519179821014404 0.9245759844779968 0.9503390192985536 0.0 0.0 0.0 0.0 53.485170968842795 55.00000000000001 0.0 no 3897 chrVII_119140r 12088 essential YGL201C 1745 + TCAATTTTTAAAATACGTAG Q|583|E Q|583|* MCM6 MiniChromosome Maintenance 1017.0 0 0 0 0 -0.3864559921711041 P53091 0.9453110098838806 0.0 30.347985816052127 20.0 0.0 no 3898 chrVII_119292r 12093 essential YGL201C 1593 + TCTATTGCTCCAGCTGTGTT S|532|C S|532|F MCM6 MiniChromosome Maintenance 1017.0 0 0 0 0 0.3661836625905618 P53091 0.9136430025100708 0.818576991558075 0.0 0.0 55.035355919976276 45.0 0.0 no 3899 chrVII_119455r 12094 essential YGL201C 1430 + CCGAGAAACTGAACTACAGA R|478|G R|478|* MCM6 MiniChromosome Maintenance 1017.0 0 0 0 0 -1.6950219922685077 P53091 0.9572200179100036 0.3766768574714661 40.872353217013774 45.0 0.0 no 3900 chrVII_119542r 12097 essential YGL201C 1343 + GACATACAAGATTAGCTTTC T|449|R T|449|I Y|450|* silent|TAC>TAT|Y|450 MCM6 MiniChromosome Maintenance 1017.0 0 0 0 0 0.6654098722972478 P53091 0.8169419765472412 0.9039729833602904 0.0031404132023453712 0.003520992584526539 39.77496928841981 35.0 0.0 no 3901 chrVII_119707 12101 essential YGL201C 1181 - CCACACCCGTAAATTTGCAA V|400|L V|400|M silent|GTG>GTC|V|400 silent|GTG>GTA|V|400 MCM6 MiniChromosome Maintenance 1017.0 0 0 0 0 -0.34089588044273444 P53091 1.0068800449371338 1.019070029258728 0.2635628581047058 0.2598296105861664 47.87501182394914 45.0 0.0 no 3902 chrVII_119982 12108 essential YGL201C 906 - AAGCTTGCCTTGTATAATTC S|308|T S|308|N MCM6 MiniChromosome Maintenance 1017.0 0 0 0 0 -0.5899405930247954 P53091 1.0204199552536009 0.9620019793510436 1.0 0.09561876952648164 44.19096955708125 35.0 0.0 no 3903 chrVII_119986 12109 essential YGL201C 902 - TTGCCTTGTATAATTCTGGA A|307|P A|307|T K|306|N silent|AAG>AAA|K|306 MCM6 MiniChromosome Maintenance 1017.0 0 0 0 0 0.9608696725801279 P53091 0.8715530037879944 0.9618729948997498 0.946892023086548 0.031793978065252304 0.022279633209109303 0.3115890324115753 45.61566532922308 35.0 0.0 no 3904 chrVII_120075 12111 essential YGL201C 813 - TCACGAATTCTGTGAACTGT R|277|P R|277|H D|278|H D|278|N MCM6 MiniChromosome Maintenance 1017.0 0 0 0 0 0.2445475541733229 P53091 0.8114060163497925 0.8462460041046143 1.0558099746704102 1.0903700590133667 0.0 0.0 0.04043841361999512 0.1199161559343338 42.97000928811474 40.0 0.0 no 3905 chrVII_120130r 12112 essential YGL201C 755 + TTCTACGTCACCTGAACAGA S|253|C S|253|F T|254|R T|254|M MCM6 MiniChromosome Maintenance 1017.0 0 1 0 0 -0.3923725339545483 P53091 0.8409389853477478 0.9335389733314514 0.9502400159835817 0.9468219876289368 47.00068335918371 45.0 0.0 no 3906 chrVII_120234r 12117 essential YGL201C 651 + CAACAGGACGATGATATGAA Q|219|E Q|219|* MCM6 MiniChromosome Maintenance 1017.0 0 0 0 0 -1.2422734055707314 P53091 1.0801500082015991 0.9996469616889954 38.31408278363653 40.0 0.0 no 3907 chrVII_120620 12127 essential YGL201C 268 - AGCTCTACTTTTGAAGCTTC A|96|P A|96|T R|95|T R|95|K MCM6 MiniChromosome Maintenance 1017.0 0 1 0 0 -0.2215656194363615 P53091 1.0192400217056274 0.9998000264167786 0.9623280167579652 1.0223499536514282 0.2922058403491974 0.5926446914672852 0.162804514169693 0.6450836062431335 46.66095820753702 40.0 0.0 no 3908 chrVII_120692r 12132 essential YGL201C 193 + CCACTCAGTTTAGTTCTCAA T|66|S T|66|I silent|TCC>TCG|S|65 silent|TCC>TCT|S|65 MCM6 MiniChromosome Maintenance 1017.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.25512246965725616 P53091 1.0131200551986694 1.0088599920272827 0.8169574737548828 0.20080722868442533 48.14800771499114 40.0 0.0 no 3909 chrVII_120822 12135 essential YGL201C 66 - AAGCCAGCACCTATCGACGA G|28|A G|28|D G|28|R G|28|S MCM6 MiniChromosome Maintenance 1017.0 0 0 0 0 0.060575895361731275 P53091 0.98615700006485 0.960860013961792 0.8903049826622009 1.0178300142288208 52.665851840868356 55.00000000000001 0.0 no 3910 chrVII_120831r 12139 essential YGL201C 54 + TCTCCGCCACCATCGTCGAT P|20|A P|20|S S|19|C S|19|F MCM6 MiniChromosome Maintenance 1017.0 0 1 0 0 -4.148248699792372 P53091 1.118749976158142 1.0799399614334106 0.862089991569519 0.889028012752533 59.338174111456006 60.0 0.0 yes 3911 chrVII_171867 12143 no_effect YGL176C 1193 - TTTCGGTCAGAATGTCCTCC E|404|Q E|404|K 0 0 0 0 -0.065862560276089 P46945 0.5667980313301086 0.6408768892288208 53.09092618432896 50.0 0.0 no 3912 chrVII_171933r 12145 no_effect YGL176C 1124 + CCTAATACTTATATCTGGAA L|376|V silent|CTA>TTA|L|376 0 0 0 0 0.164522019443871 P46945 0.4345608949661255 38.79290305982357 30.0 0.0 no 3913 chrVII_172037r 12147 no_effect YGL176C 1020 + TTACAGTACTCCAAGACCAA Q|342|E Q|342|* 0 0 0 0 0.5188500110251748 P46945 0.7455617785453796 44.95145136074069 40.0 0.0 no 3914 chrVII_172130r 12149 no_effect YGL176C 927 + CCTTTAAAAAAAACGAACAC P|310|R P|310|L 0 0 0 0 1.439067202006847 P46945 31.175148760323964 30.0 0.0 no 3915 chrVII_172563r 12155 no_effect YGL176C 494 + TTTCTTTACGGGGTTTTCCA F|166|L silent|TTC>TTT|F|166 0 0 0 0 0.4038141717009325 P46945 0.8097169995307922 50.96001714585708 40.0 0.0 no 3916 chrVII_172588 12157 no_effect YGL176C 472 - TTCTTCAGAAAAATTATCCA E|164|Q E|164|K E|163|Q E|163|K 0 0 0 0 -0.8119760934723815 P46945 0.3919639885425568 0.5967581868171692 0.2907191812992096 0.32449695467948914 36.35344544193879 25.0 0.0 no 3917 chrVII_172706 12159 no_effect YGL176C 354 - ACTCCTATCTGTATCCTGTG G|124|A G|124|E V|125|L V|125|I 0 0 0 0 0.40548313765700017 P46945 0.20746739208698275 0.2694544196128845 0.3428609371185303 0.2196292132139206 51.95142871901066 45.0 0.0 no 3918 chrVII_172772r 12161 no_effect YGL176C 285 + GCATCGCATTCTCTCACTGA A|96|G A|96|V S|97|W S|97|L 0 0 0 0 0.1866360040805202 P46945 0.4151076972484589 0.4422958493232727 0.1852330416440964 0.6706036925315857 53.2738812848205 50.0 0.0 no 3919 chrVII_172720r 12162 no_effect YGL176C 337 + AATCACTCAATTTTCCACAC S|114|* S|114|L L|115|V L|115|F 0 0 0 0 -0.7382683521810773 P46945 0.30324676632881165 0.4359998404979706 0.04746482521295548 42.222945408839 35.0 0.0 no 3920 chrVII_172848r 12165 no_effect YGL176C 209 + TCTTCTGAATCCGTTGGAAA L|71|V L|71|F L|72|V silent|CTG>TTG|L|72 0 0 0 0 -0.9748781557249648 P46945 0.8860687017440796 0.13658174872398374 0.5842934846878052 44.19247840584956 40.0 0.0 no 3921 chrVII_172991r 12167 no_effect YGL176C 66 + AATCAAAGCATTTCTACCAC Q|24|E Q|24|* 0 0 0 0 0.3435289433770038 P46945 40.96666201210047 35.0 0.0 no 3922 chrVII_180718 12169 essential YGL172W 18 + GCATCTTCGACACCTGCAGG A|7|G A|7|V S|8|C S|8|F NUP49 NUclear Pore 472.0 0 0 0 0 0.6957381817723389 Q02199 0.11731118708848952 0.0960993692278862 0.05549326166510582 0.057559121400117874 55.83787632070943 60.0 1.0 no 3923 chrVII_180719 12170 essential YGL172W 19 + CATCTTCGACACCTGCAGGT S|8|C S|8|F S|9|W S|9|L NUP49 NUclear Pore 472.0 0 0 0 0 -0.4121156751323688 Q02199 0.05549326166510582 0.057559121400117874 0.029262671247124675 0.2673183381557465 54.81559286002778 55.00000000000001 1.0 no 3924 chrVII_180973 12191 essential YGL172W 273 + CCTAACAATACGGCGAACAC P|92|R P|92|L N|93|K silent|AAC>AAT|N|93 NUP49 NUclear Pore 472.0 0 0 0 0 0.3566530653630284 Q02199 0.22224879264831546 0.12530072033405304 0.08486583828926086 43.52815965552775 50.0 1.0 no 3925 chrVII_180973r 12192 essential YGL172W 276 - CCAGTGTTCGCCGTATTGTT G|99|R G|99|R NUP49 NUclear Pore 472.0 0 0 0 0 -4.1044257051151085 Q02199 0.08593899756669998 0.08593899756669998 55.622154323888644 50.0 1.0 yes 3926 chrVII_180975 12193 essential YGL172W 275 + TAACAATACGGCGAACACTG N|93|K silent|AAC>AAT|N|93 NUP49 NUclear Pore 472.0 0 0 0 0 0.2904200427802732 Q02199 0.08486583828926086 40.20455856436229 45.0 1.0 no 3927 chrVII_181049r 12198 essential YGL172W 352 - ACGACTCGTCTGTGCATTGT R|124|P R|124|H S|123|T S|123|N NUP49 NUclear Pore 472.0 0 0 0 0 0.761693310258465 Q02199 0.28032049536705017 0.17754358053207395 1.0 0.4352841675281525 52.27543127888134 50.0 1.0 no 3928 chrVII_181051 12199 essential YGL172W 351 + AACAATGCACAGACGAGTCG N|118|K silent|AAC>AAT|N|118 NUP49 NUclear Pore 472.0 0 0 0 0 1.0357727589415058 Q02199 0.3620569109916687 43.69682871324437 50.0 1.0 no 3929 chrVII_181159r 12201 essential YGL172W 462 - AACAAAGAAGTGCCTCCTGC L|160|F silent|TTG>TTA|L|160 NUP49 NUclear Pore 472.0 0 0 0 0 0.2564508189526808 Q02199 0.10818816721439363 48.124221788502034 50.0 1.0 no 3930 chrVII_181283r 12210 essential YGL172W 586 - GCCAAATAACCCTCCACCAG G|202|R G|202|S G|202|A G|202|D NUP49 NUclear Pore 472.0 0 0 0 0 -1.3409091917995717 Q02199 0.0376020297408104 0.3441447913646698 0.08184043318033217 0.19324533641338348 53.44494984150764 55.00000000000001 1.0 no 3931 chrVII_181481r 12219 essential YGL172W 784 - TTCGGAAATCCGTGTCATTG E|268|Q E|268|K NUP49 NUclear Pore 472.0 0 0 0 0 -0.1909483216820404 Q02199 0.07745811343193054 0.062089953571558 45.82388463393528 45.0 1.0 no 3932 chrVII_181563 12221 essential YGL172W 863 + GCAGATCTCGCACCATTTGA Q|289|E Q|289|* I|290|M silent|ATC>ATT|I|290 NUP49 NUclear Pore 472.0 0 0 0 0 0.30636877983053684 Q02199 0.5090821981430054 0.035113055258989334 52.667912539819724 50.0 1.0 no 3933 chrVII_181700r 12222 essential YGL172W 1003 - ATCGATTAGCGATTTAAATG D|341|H D|341|N NUP49 NUclear Pore 472.0 0 0 0 0 0.2633815920940197 Q02199 0.019262967631220814 0.08185554295778275 36.22185217620137 30.0 1.0 no 3934 chrVII_182443r 12227 essential YGL171W 56 - AATCTGCTGCCTTAGCCTTT D|25|H D|25|N A|24|P A|24|T ROK1 Rescuer Of Kem1 564.0 0 0 0 0 -0.4170243316251675 P45818 0.11839345097541808 0.4505794644355774 0.18782781064510345 0.46283873915672297 54.96267857304297 45.0 1.0 no 3935 chrVII_182599 12230 essential YGL171W 209 + AAACGATTCTCCAAACAAAG N|71|K silent|AAC>AAT|N|71 ROK1 Rescuer Of Kem1 564.0 0 1 0 0 0.9040927918425864 P45818 0.8828772306442261 35.570173062340935 35.0 1.0 no 3936 chrVII_182609r 12231 essential YGL171W 222 - CCGCTCTTCTCCTCTTTGTT S|80|T S|80|N G|81|R G|81|S ROK1 Rescuer Of Kem1 564.0 0 0 0 0 -0.5342741410774768 P45818 0.4513416588306427 0.4306998550891876 0.5261104106903076 0.7125697731971741 59.01536477723118 50.0 1.0 no 3937 chrVII_182670r 12234 essential YGL171W 283 - TCTCAACGCGGATGCCTCAA L|100|F silent|TTG>TTA|L|100 R|101|T R|101|K ROK1 Rescuer Of Kem1 564.0 0 0 0 0 -0.10599283614484004 P45818 1.0 0.017845498397946358 0.10826314240694046 -0.1005999967455864 -0.5803999900817871 52.32829737285607 55.00000000000001 1.0 no 3938 chrVII_182849r 12239 essential YGL171W 462 - TCTCTATTATTCAAAGCAAC R|160|T R|160|K D|161|H D|161|N ROK1 Rescuer Of Kem1 564.0 0 0 0 0 -0.034742776084312615 P45818 0.0 0.0 0.013770884834229946 0.0907067358493805 37.47546580381049 30.0 1.0 no 3939 chrVII_182889r 12242 essential YGL171W 502 - TAACGTCTTACCAGACCCTG silent|ACG>ACC|T|173 silent|ACG>ACA|T|173 K|172|N silent|AAG>AAA|K|172 ROK1 Rescuer Of Kem1 564.0 0 0 0 0 -3.2926996331340304 P45818 0.0 50.30082958420371 50.0 1.0 yes 3940 chrVII_183031 12244 essential YGL171W 641 + GCTATCTTACAAGATATTTT L|215|V silent|CTA>TTA|L|215 S|216|C S|216|F ROK1 Rescuer Of Kem1 564.0 0 0 0 0 0.1247601411964438 P45818 0.384994775056839 0.01014142669737339 0.005355968605726957 38.226731064287435 25.0 1.0 no 3941 chrVII_183077 12245 essential YGL171W 687 + GCACTCTTATCTAAATCTTT L|231|V L|231|F A|230|G A|230|V ROK1 Rescuer Of Kem1 564.0 0 0 0 0 -0.009146511955395759 P45818 0.8915373682975769 0.0433758907020092 0.5854400396347046 0.6403509378433228 -4.02899980545044 4.718599796295166 0.4749999940395355 -0.6502000093460083 41.40387067924206 30.0 1.0 no 3942 chrVII_183299r 12249 essential YGL171W 912 - AACATCGCTTTACGCAACGA M|310|I M|310|I silent|GCG>GCC|A|309 silent|GCG>GCA|A|309 ROK1 Rescuer Of Kem1 564.0 0 0 0 0 -1.1473279921247623 P45818 0.04755083844065666 0.04755083844065666 45.05270778800377 45.0 1.0 no 3943 chrVII_183335r 12250 essential YGL171W 948 - GCAATCTCTTCTACATTGGA A|323|P A|323|T E|321|D silent|GAG>GAA|E|321 ROK1 Rescuer Of Kem1 564.0 0 0 0 0 0.5358684018987491 P45818 0.09962563961744307 0.08333493024110794 0.2138497978448868 4.633399963378906 0.8673999905586243 46.4639917184436 40.0 1.0 no 3944 chrVII_186150r 12257 essential YGL169W 94 - ACCATCTATATGCGCATCAG G|38|R G|38|S G|38|A G|38|D SUA5 Suppressor of Upstream AUG 426.0 0 0 0 0 -1.2393535816584924 P32579 0.5288249254226685 0.7862334847450256 0.7716436386108398 0.6269503831863403 48.62642681238288 45.0 1.0 no 3945 chrVII_186152r 12258 essential YGL169W 96 - GAACCATCTATATGCGCATC G|38|A G|38|D G|38|R G|38|S SUA5 Suppressor of Upstream AUG 426.0 0 0 0 0 0.7627388147696621 P32579 0.7716436386108398 0.6269503831863403 0.5288249254226685 0.7862334847450256 46.922585098165825 45.0 1.0 no 3946 chrVII_186181 12259 essential YGL169W 122 + AACGATAACAGATCCTGAAA T|42|R T|42|M SUA5 Suppressor of Upstream AUG 426.0 0 0 0 0 -0.002619457217201998 P32579 0.5564247369766235 0.13810288906097412 37.352934364248206 35.0 1.0 no 3947 chrVII_186194r 12260 essential YGL169W 138 - ACTAGCGCTGCTTCCGTTTC V|53|L V|53|I silent|GCG>GCC|A|51 silent|GCG>GCA|A|51 SUA5 Suppressor of Upstream AUG 426.0 0 0 0 0 -0.3786512747217158 P32579 0.3683957159519196 0.22379612922668454 57.27310821464989 55.00000000000001 1.0 no 3948 chrVII_186260 12262 essential YGL169W 201 + TTTCCAACCGAAACTGTTTA P|69|A P|69|S P|69|R P|69|L SUA5 Suppressor of Upstream AUG 426.0 0 0 0 0 0.5096578850140343 P32579 0.0 0.0 0.0 0.0 42.974109683114186 35.0 1.0 no 3949 chrVII_186310 12267 essential YGL169W 251 + TTCAGTGCTTAGTATATACA S|85|* S|85|L SUA5 Suppressor of Upstream AUG 426.0 0 0 0 0 -4.5452671059647765 P32579 0.004669161047786474 42.01779761231643 30.0 1.0 yes 3950 chrVII_186552r 12268 essential YGL169W 496 - CGCAAACGTAGGCTGATCTG A|172|P A|172|T silent|ACG>ACC|T|170 silent|ACG>ACA|T|170 SUA5 Suppressor of Upstream AUG 426.0 0 0 0 0 -3.944854801921873 P32579 0.016286145895719528 0.011253143660724165 -1.181399941444397 1.1829999685287476 47.69803267766422 55.00000000000001 1.0 yes 3951 chrVII_186685 12279 essential YGL169W 626 + TCATGTTTATCATGATCTAA H|210|D H|210|Y SUA5 Suppressor of Upstream AUG 426.0 0 0 0 0 -0.32348636761270744 P32579 0.0 0.0 37.9988564037165 25.0 1.0 no 3952 chrVII_186956 12288 essential YGL169W 897 + TTACTAGTTCCTCATTGCGA L|301|V silent|CTA>TTA|L|301 SUA5 Suppressor of Upstream AUG 426.0 0 0 0 0 0.6688689738483558 P32579 0.0721350908279419 1.9381999969482424 48.87067316584006 40.0 1.0 no 3953 chrVII_186962 12289 essential YGL169W 903 + GTTCCTCATTGCGAAGGCGA P|303|A P|303|S P|303|R P|303|L SUA5 Suppressor of Upstream AUG 426.0 0 0 0 0 -1.44225854996124 P32579 0.8478092551231384 0.8811166882514954 0.4989993870258331 0.4649654030799866 53.90772261709242 55.00000000000001 1.0 no 3954 chrVII_188475 12297 high_effect YGL167C 1974 - ACAATGTTTAACTTATGCTC V|665|L V|665|I PMR1 Plasma Membrane ATPase Related 950.0 0 0 0 0 0.16614500938370286 P13586 0.020207881927490238 0.753790557384491 38.82978746409333 30.0 0.0 no 3955 chrVII_188574r 12299 high_effect YGL167C 1872 + CCAAAGCTTTCCGTTTTATC P|625|R P|625|L L|627|V L|627|F PMR1 Plasma Membrane ATPase Related 950.0 0 0 0 0 -0.6443746493736735 P13586 0.4369322955608368 0.25209668278694153 0.2820528745651245 0.05072929710149765 47.081448428580934 40.0 0.0 no 3956 chrVII_188679r 12301 high_effect YGL167C 1767 + ATCGAACAATTACTACAAGG I|590|M silent|ATC>ATT|I|590 Q|592|E Q|592|* PMR1 Plasma Membrane ATPase Related 950.0 0 0 0 0 1.1782021655691108 P13586 0.003569790394976735 1.0 36.27731457563596 35.0 0.0 no 3957 chrVII_188697 12302 high_effect YGL167C 1752 - TCGATGGCAAATTTAACGTT E|591|Q E|591|K PMR1 Plasma Membrane ATPase Related 950.0 0 0 0 0 0.0954789970897002 P13586 0.6031205654144287 0.9012277126312256 40.340881504456895 35.0 0.0 no 3958 chrVII_188703 12303 high_effect YGL167C 1746 - GCAAATTTAACGTTCGGTCT A|589|P A|589|T PMR1 Plasma Membrane ATPase Related 950.0 0 0 0 0 0.5324241188064864 P13586 0.01251455955207348 0.10221268981695177 44.02382956413425 40.0 0.0 no 3959 chrVII_188748r 12304 high_effect YGL167C 1698 + ATCAAAGATTTAACCTTTAC I|567|M silent|ATC>ATT|I|567 PMR1 Plasma Membrane ATPase Related 950.0 0 0 0 0 0.4683414884966847 P13586 0.2322686016559601 35.200889727866866 25.0 0.0 no 3960 chrVII_188863 12306 high_effect YGL167C 1586 - ACTCATTTATCGTAGCTTTT E|535|Q E|535|K E|535|D silent|GAG>GAA|E|535 PMR1 Plasma Membrane ATPase Related 950.0 0 1 0 0 0.35945118253400776 P13586 0.9329873323440552 0.8071053624153137 0.6029030084609985 44.23197350011196 30.0 0.0 no 3961 chrVII_188864 12307 high_effect YGL167C 1585 - CTCATTTATCGTAGCTTTTT E|535|Q E|535|K PMR1 Plasma Membrane ATPase Related 950.0 0 1 0 0 1.2789856475038663 P13586 0.9329873323440552 0.8071053624153137 44.035737563749244 30.0 0.0 no 3962 chrVII_188976 12308 high_effect YGL167C 1473 - ACTGTACACTTATTGTCGAC V|498|L V|498|I C|496|S C|496|Y PMR1 Plasma Membrane ATPase Related 950.0 0 0 0 0 0.36847084551200815 P13586 0.6455740332603455 0.3934201300144196 0.4548553824424744 0.02045281603932381 43.822085404123136 40.0 0.0 no 3963 chrVII_189133r 12311 high_effect YGL167C 1313 + TCAAGAACATGCCATATTTC Q|439|E Q|439|* PMR1 Plasma Membrane ATPase Related 950.0 0 0 0 0 0.17823988003441024 P13586 0.9875625371932985 41.35101601922275 35.0 0.0 no 3964 chrVII_189378 12314 high_effect YGL167C 1071 - GAGCCTAAAGTTTCGACACT G|363|A G|363|D G|363|R G|363|S PMR1 Plasma Membrane ATPase Related 950.0 0 0 0 0 -1.8229471573216307 P13586 0.01570634543895721 0.003586596110835672 0.001532203983515501 0.03825030103325844 46.695218339172925 45.0 0.0 no 3965 chrVII_189395 12316 high_effect YGL167C 1054 - ACTTGGTAACCTTCTCACGA S|358|T S|358|N PMR1 Plasma Membrane ATPase Related 950.0 0 0 0 0 -0.3958915584142828 P13586 0.5525712370872498 0.09350735694169998 48.86792772216819 45.0 0.0 no 3966 chrVII_189445r 12319 high_effect YGL167C 1001 + TGTCACTGTTACTTTGGCAT silent|GTC>GTG|V|335 silent|GTC>GTT|V|335 T|336|S T|336|I PMR1 Plasma Membrane ATPase Related 950.0 0 0 0 0 0.4149087807292298 P13586 0.014711389318108559 0.0033499386627227072 48.941093141974925 40.0 0.0 no 3967 chrVII_189499r 12322 high_effect YGL167C 947 + CCAAATATCGGTATCCTTAG Q|317|E Q|317|* PMR1 Plasma Membrane ATPase Related 950.0 0 0 0 0 0.624722755405677 P13586 0.010464735329151155 43.82144071206358 40.0 0.0 no 3968 chrVII_189897 12330 high_effect YGL167C 552 - TCAATAATTCTAATGTCTGC E|191|Q E|191|K PMR1 Plasma Membrane ATPase Related 950.0 0 0 0 0 0.8292065168327217 P13586 0.14221885800361633 0.5461581945419312 37.85758065007616 30.0 0.0 no 3969 chrVII_189961r 12332 high_effect YGL167C 485 + TCATGTACTGGCTTCCACCT H|163|D H|163|Y PMR1 Plasma Membrane ATPase Related 950.0 0 0 0 0 0.5714112324159318 P13586 0.6546905636787415 0.04148292541503906 56.41755107178535 50.0 0.0 no 3970 chrVII_189999 12333 high_effect YGL167C 450 - CTCATTAAGTGACATTCAGC M|156|I M|156|I PMR1 Plasma Membrane ATPase Related 950.0 0 0 0 0 -0.18439096326870885 P13586 1.0 1.0 43.284482601336386 40.0 0.0 no 3971 chrVII_190150r 12336 high_effect YGL167C 296 + ACTTTTAATAGGATCCGCAG L|100|V L|100|F PMR1 Plasma Membrane ATPase Related 950.0 0 0 0 0 0.171293911392549 P13586 0.0052964859642088405 0.005204002372920513 44.398047490448505 40.0 0.0 no 3972 chrVII_190229 12338 high_effect YGL167C 220 - ATCTTCTACGGTTATTTCAT D|80|H D|80|N E|79|Q E|79|K PMR1 Plasma Membrane ATPase Related 950.0 0 0 0 0 0.3420025079724528 P13586 0.06749530881643295 0.2845900058746338 0.3162028193473816 0.5313948392868042 43.609494361087464 30.0 0.0 no 3973 chrVII_190302r 12341 high_effect YGL167C 144 + AAACTGGACACTGACAAAAA L|50|V silent|CTG>TTG|L|50 PMR1 Plasma Membrane ATPase Related 950.0 0 1 0 0 0.3835706506020561 P13586 0.08521056175231934 34.56591749568907 35.0 0.0 no 3974 chrVII_190399 12343 high_effect YGL167C 50 - CATCTAGTATTTCTCTCTCA D|23|H D|23|N PMR1 Plasma Membrane ATPase Related 950.0 0 0 0 0 0.3878597075323139 P13586 0.1766742318868637 0.7055408954620361 46.232393980247366 35.0 0.0 no 3975 chrVII_190434 12345 high_effect YGL167C 15 - TCAAGAAGACTCGCATTAAA D|12|H D|12|N PMR1 Plasma Membrane ATPase Related 950.0 0 0 0 0 0.2623802101719718 P13586 0.008312586694955826 0.03009041212499142 37.73382248340153 35.0 0.0 no 3976 chrVII_214094r 12346 essential YGL155W 16 - CACAACTCTACTCGGGCCAT V|12|L V|12|M V|11|L V|11|I CDC43 Cell Division Cycle 376.0 0 0 0 0 -0.6551312212072681 P18898 0.33550530672073364 0.11687047779560088 1.0 0.9939041137695312 -1.027999997138977 -0.9828000068664552 -0.2596000134944916 -0.6913999915122986 52.94631110404083 55.00000000000001 1.0 no 3977 chrVII_214712 12355 essential YGL155W 631 + CCCACAATGAACCACACTCA H|212|D H|212|Y silent|GCC>GCG|A|211 silent|GCC>GCT|A|211 CDC43 Cell Division Cycle 376.0 0 0 0 0 0.17343572217465525 P18898 0.0925360694527626 1.0 -0.15760000050067902 -0.17960000038146973 49.49616834282796 50.0 1.0 no 3978 chrVII_214817r 12358 essential YGL155W 739 - TACTTGCCTATGTAATAGCC V|253|L V|253|I R|251|S silent|AGG>AGA|R|251 CDC43 Cell Division Cycle 376.0 0 0 0 0 0.3643339630908283 P18898 0.03945532813668251 0.4087887406349182 0.0 -0.13899999856948853 -0.6930000185966492 47.38750582542349 40.0 1.0 no 3979 chrVII_214845r 12359 essential YGL155W 767 - TTTCAAATTTCATACATCCA E|262|Q E|262|K CDC43 Cell Division Cycle 376.0 0 0 0 0 0.3481692710724953 P18898 0.3201430141925812 0.26010116934776306 39.31142758489676 25.0 1.0 no 3980 chrVII_214893 12361 essential YGL155W 812 + ATCTGATGATGGCGGTTTCC S|272|C S|272|F CDC43 Cell Division Cycle 376.0 0 0 0 0 0.8470070407799564 P18898 0.18931926786899567 0.4939764738082886 52.0100764064245 50.0 1.0 no 3981 chrVII_222238 12363 essential YGL150C 3316 - TTTCACGTTCTTCAGTTTAT silent|GTG>GTC|V|1111 silent|GTG>GTA|V|1111 V|1111|L V|1111|M INO80 INOsitol requiring 1489.0 0 0 0 0 -0.11678752039398982 P53115 0.9539830088615416 0.9587630033493042 0.6606048345565796 0.22478921711444852 44.404443577815016 30.0 0.0 no 3982 chrVII_222300 12364 essential YGL150C 3254 - CTTCATAAATCAACCTTGGT E|1091|Q E|1091|K INO80 INOsitol requiring 1489.0 0 0 0 0 0.3190323975421203 P53115 0.956179976463318 0.9475290179252625 0.41225048899650574 0.393331378698349 42.16084689212761 35.0 0.0 no 3983 chrVII_222371r 12366 essential YGL150C 3180 + AGCAGTAATAATATTTCCAA S|1061|R silent|AGC>AGT|S|1061 INO80 INOsitol requiring 1489.0 0 0 0 0 0.04673504450438512 P53115 0.9417110085487366 0.3046850860118866 37.50656533163999 25.0 0.0 no 3984 chrVII_223012r 12376 essential YGL150C 2539 + AATCTTCACAGTCATCTAGA S|848|C S|848|F S|849|* S|849|L INO80 INOsitol requiring 1489.0 0 0 0 0 -0.9443362876891518 P53115 0.945252001285553 0.9294660091400146 0.9298099875450134 0.0007259614649228753 0.0004657066601794213 0.001049401704221964 43.11512409971567 35.0 0.0 no 3985 chrVII_222938 12378 essential YGL150C 2616 - TCCTGCATACTGTTTTGGAT Q|878|H silent|CAG>CAA|Q|878 E|879|Q E|879|K INO80 INOsitol requiring 1489.0 0 0 0 0 -2.1814766369883856 P53115 0.9570760130882264 0.956179976463318 0.9475290179252625 0.0916510373353958 0.003326902631670237 0.0031294673681259155 49.584346980311295 40.0 0.0 yes 3986 chrVII_223183r 12384 essential YGL150C 2368 + CCAATGACCGTAAAGTTCTT silent|GCC>GCG|A|790 silent|GCC>GCT|A|790 INO80 INOsitol requiring 1489.0 0 0 0 0 1.4981037594117743 P53115 44.42834154238818 40.0 0.0 no 3987 chrVII_223199 12385 essential YGL150C 2355 - TCATTGGCATTACCCCAGTA D|792|H D|792|N INO80 INOsitol requiring 1489.0 0 0 0 0 -1.3523217261548208 P53115 0.9486550092697144 0.956179976463318 0.0009128145175054668 0.002610695781186223 54.077255566039135 45.0 0.0 no 3988 chrVII_223263r 12386 essential YGL150C 2288 + CGCTTCTACTCTGCATAACT A|764|G A|764|V S|765|C S|765|F INO80 INOsitol requiring 1489.0 0 0 0 0 -1.1318460043482217 P53115 0.9484469890594482 0.9504740238189696 0.945252001285553 0.9294660091400146 0.006817707326263189 0.002494259737432003 0.00114877219311893 0.00046892240061424667 48.61670919707132 45.0 0.0 no 3989 chrVII_223404r 12394 essential YGL150C 2147 + GCTAGCTAACCTTTACGACC L|717|V silent|CTA>TTA|L|717 A|718|G A|718|V INO80 INOsitol requiring 1489.0 0 0 0 0 -0.06284289616985342 P53115 0.9512209892272948 0.9484469890594482 0.9504740238189696 0.003531910944730044 0.06897913664579391 0.2029844969511032 50.563917951383466 50.0 0.0 no 3990 chrVII_223467r 12395 essential YGL150C 2084 + CATCGAGCAACCAAAGATTT I|696|M silent|ATC>ATT|I|696 INO80 INOsitol requiring 1489.0 0 0 0 0 0.5773535483416289 P53115 0.9598389863967896 0.028387919068336487 42.07635606905143 40.0 0.0 no 3991 chrVII_223540 12397 essential YGL150C 2014 - CTCTTCTTCCTCATGCGCAT E|678|Q E|678|K E|677|Q E|677|K INO80 INOsitol requiring 1489.0 0 0 0 0 -0.00294767492775843 P53115 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.5095002055168152 0.8391774892807007 0.5379759669303894 0.8714893460273743 56.22077311248012 50.0 0.0 no 3992 chrVII_224032 12400 essential YGL150C 1522 - GGCTTCTCTAGCACAAAGTG A|514|P A|514|T E|513|Q E|513|K INO80 INOsitol requiring 1489.0 0 0 0 0 -0.19433313027590096 P53115 0.9573720097541808 0.9523990154266356 0.956179976463318 0.9475290179252625 0.017828598618507385 0.018752880394458767 0.145718052983284 0.011917006224393845 48.88774943718215 50.0 0.0 no 3993 chrVII_224201 12402 essential YGL150C 1353 - TTCATTTTCATGCCGTAAGT M|457|I M|457|I INO80 INOsitol requiring 1489.0 0 0 0 0 -0.5817107841530079 P53115 0.9553959965705872 0.9553959965705872 0.4451577663421631 0.4451577663421631 46.617939593506954 35.0 0.0 no 3994 chrVII_224681 12407 essential YGL150C 873 - TTTCTCCTTTTCTCGACATC R|297|T R|297|K R|296|S silent|AGG>AGA|R|296 INO80 INOsitol requiring 1489.0 0 0 0 0 0.8851651689246003 P53115 0.932735025882721 0.955805003643036 0.9087679982185364 0.12952297925949094 0.7966894507408142 0.12883032858371735 49.16776980697046 40.0 0.0 no 3995 chrVII_225378 12413 essential YGL150C 176 - TCGAATCCCTTCTCTTGATA silent|TCG>TCC|S|65 silent|TCG>TCA|S|65 D|64|H D|64|N INO80 INOsitol requiring 1489.0 0 0 0 1 0.6386864787976188 P53115 0.9486550092697144 0.956179976463318 48.31005759382907 40.0 0.0 no 3996 chrVII_225448 12417 essential YGL150C 106 - CACTCTGGTGGGCGCCACAT V|42|L V|42|M R|41|T R|41|K INO80 INOsitol requiring 1489.0 0 0 0 0 -0.8087328766978088 P53115 0.9539830088615416 0.9587630033493042 0.932735025882721 0.955805003643036 60.3722483828094 65.0 0.0 no 3997 chrVII_230349r 12419 essential YGL145W 109 - TGCTACTTCTGTGTCATTGC A|43|P A|43|T V|42|L V|42|I TIP20 SEC20 (Twenty) Interacting Protein 701.0 0 0 0 0 -0.07632991834514223 P33891 0.9573720097541808 0.9523990154266356 0.9539830088615416 0.9574310183525084 0.2177546918392181 0.5090770125389099 0.3719819486141205 0.2293373942375183 51.317111733032895 45.0 1.0 no 3998 chrVII_230389 12422 essential YGL145W 146 + ACAAGATATTATTGAAGTAG Q|50|E Q|50|* TIP20 SEC20 (Twenty) Interacting Protein 701.0 0 0 0 0 0.19657309474278845 P33891 0.9590039849281312 1.0 32.001456508011984 25.0 1.0 no 3999 chrVII_230866 12430 essential YGL145W 623 + TCTGCTCTACTTACCTTTGG L|209|V silent|CTG>TTG|L|209 L|210|V L|210|F TIP20 SEC20 (Twenty) Interacting Protein 701.0 0 0 0 0 0.06597131406327708 P33891 0.9512209892272948 0.9512209892272948 0.9587849974632264 0.35384878516197205 0.12995824217796326 0.21354566514492035 51.04308979062864 45.0 1.0 no 4000 chrVII_230869 12431 essential YGL145W 626 + GCTCTACTTACCTTTGGAGG silent|CTC>CTG|L|210 silent|CTC>CTT|L|210 L|210|V L|210|F TIP20 SEC20 (Twenty) Interacting Protein 701.0 0 0 0 0 -0.05935335548619298 P33891 0.9512209892272948 0.9587849974632264 0.12995824217796326 0.21354566514492035 51.913502981483994 50.0 1.0 no 4001 chrVII_230973 12432 essential YGL145W 730 + TAGCAAACAATTTCAACGTT A|245|G A|245|V TIP20 SEC20 (Twenty) Interacting Protein 701.0 0 0 0 0 -0.04767455331886997 P33891 0.9484469890594482 0.9504740238189696 0.04064179956912994 0.03744302317500114 37.340674633478436 30.0 1.0 no 4002 chrVII_231157 12433 essential YGL145W 914 + TTACGTCTTACAACCCATTA Y|306|* silent|TAC>TAT|Y|306 silent|GTC>GTG|V|307 silent|GTC>GTT|V|307 TIP20 SEC20 (Twenty) Interacting Protein 701.0 0 0 0 0 1.0390687451730116 P33891 45.012175537563 35.0 1.0 no 4003 chrVII_231170r 12434 essential YGL145W 930 - GATCTTACTTTATCCCTAAT R|316|T R|316|K TIP20 SEC20 (Twenty) Interacting Protein 701.0 0 0 0 0 0.8956122000892432 P33891 0.932735025882721 0.955805003643036 0.3691138029098511 1.0 43.58563693905722 30.0 1.0 no 4004 chrVII_231283r 12436 essential YGL145W 1043 - ACGACACCAAACCTAGCCCA silent|TCG>TCC|S|354 silent|TCG>TCA|S|354 silent|GTG>GTC|V|353 silent|GTG>GTA|V|353 TIP20 SEC20 (Twenty) Interacting Protein 701.0 0 0 0 0 -0.06772731864213638 P33891 53.36061611555454 55.00000000000001 1.0 no 4005 chrVII_231312r 12440 essential YGL145W 1072 - CCATTTCTCCCATACTTCAT W|364|S W|364|* E|362|D silent|GAG>GAA|E|362 TIP20 SEC20 (Twenty) Interacting Protein 701.0 0 0 0 0 -0.15220918415382018 P33891 0.8858469724655151 0.94931298494339 0.0 1.0 51.90567463095522 40.0 1.0 no 4006 chrVII_231783 12446 essential YGL145W 1540 + TGCAAAACTCCATTGTACAC Q|515|E Q|515|* TIP20 SEC20 (Twenty) Interacting Protein 701.0 0 0 0 0 0.2497387946454681 P33891 0.9590039849281312 0.060926228761672974 42.578231734892604 40.0 1.0 no 4007 chrVII_236757 12447 essential YGL142C 1343 - CTTCGATAGATCCAGATTCG E|454|Q E|454|K 0 0 0 0 -0.3012665113117198 P30777 0.956179976463318 0.9475290179252625 0.2858327925205231 0.4208343327045441 45.29672996686776 45.0 0.0 no 4008 chrVII_236888r 12449 essential YGL142C 1209 + TTCATATTAATATCATCATT F|404|L silent|TTC>TTT|F|404 0 0 0 0 -0.4126073542563967 P30777 0.9387490153312684 0.5112309455871582 33.54304270557162 15.0 0.0 no 4009 chrVII_237381r 12455 essential YGL142C 716 + GTCGCTTATTTTTGCATTTC S|240|W S|240|L L|241|V L|241|F 0 0 0 0 0.5126009424212603 P30777 0.9288619756698608 0.9298099875450134 0.9512209892272948 0.9587849974632264 0.0036679024342447524 0.02822088822722435 0.07083240151405333 0.051191400736570365 46.74772103858829 35.0 0.0 no 4010 chrVII_237439 12458 essential YGL142C 661 - TGTCCAGTCCCAGTAGTAGA W|226|C W|226|* W|226|S W|226|* 0 0 0 0 -1.9601524347799704 P30777 0.8858469724655151 0.8858469724655151 0.0 0.0 56.87470349952554 50.0 0.0 no 4011 chrVII_237448r 12461 essential YGL142C 649 + CTTCTATTGCCCTCTACTAC S|218|C S|218|F 0 0 0 0 -0.08628910427736636 P30777 0.945252001285553 0.9294660091400146 0.21191488206386566 0.01983771845698357 51.5933764675924 45.0 0.0 no 4012 chrVII_237649 12463 essential YGL142C 451 - TACGATATAATATTCCCCTA V|157|L V|157|I 0 0 0 0 -0.4180748854353184 P30777 0.9539830088615416 0.9574310183525084 0.2589808404445648 0.9571708440780641 42.58942113671952 30.0 0.0 no 4013 chrVII_237664r 12465 essential YGL142C 433 + TGGCAGTACTAGCTTCCATA A|146|G A|146|V 0 0 0 0 -1.367611462111887 P30777 0.9484469890594482 0.9504740238189696 0.0 0.0 52.09560998107645 45.0 0.0 no 4014 chrVII_237820r 12466 essential YGL142C 277 + TTCTTCTTCTCTCAACGATA L|94|V L|94|F L|95|V L|95|F 0 0 0 0 0.7706759553251777 P30777 0.9512209892272948 0.9587849974632264 0.9512209892272948 0.9587849974632264 0.2748169004917145 0.061923231929540634 0.6630029678344727 0.6862052083015442 44.31698912646408 35.0 0.0 no 4015 chrVII_237821r 12467 essential YGL142C 276 + CTTCTTCTTCTCTCAACGAT L|94|V L|94|F L|95|V L|95|F 0 0 0 0 0.010781805840306302 P30777 0.9512209892272948 0.9587849974632264 0.9512209892272948 0.9587849974632264 0.2748169004917145 0.061923231929540634 0.6630029678344727 0.6862052083015442 46.7656648919484 40.0 0.0 no 4016 chrVII_237997 12470 essential YGL142C 103 - AAACTCATCAGCCTGAAAGA E|40|D silent|GAG>GAA|E|40 E|40|Q E|40|K 0 0 0 0 -0.2959749350441889 P30777 0.94931298494339 0.956179976463318 0.9475290179252625 0.0 0.0 0.0 42.01665921921267 40.0 0.0 no 4017 chrVII_238030 12472 essential YGL142C 70 - AACTGCATTCAGTACTCTAA V|30|L V|30|I A|29|P A|29|T 0 0 0 0 -0.7991299487235208 P30777 0.9539830088615416 0.9574310183525084 0.9573720097541808 0.9523990154266356 1.0 0.4785033464431762 0.032476190477609634 0.038368325680494315 42.46766028333383 35.0 0.0 no 4018 chrVII_250128 12474 essential YGL137W 59 + TTTCCATCCTACTGAGCCAT F|21|L silent|TTC>TTT|F|21 H|22|D H|22|Y SEC27 SECretory 889.0 0 1 0 0 0.042731927506382834 P41811 0.9387490153312684 0.9473130106925964 0.9489949941635132 1.0 0.0 0.0 1.1505999565124512 2.286200046539306 5.09119987487793 54.29452029379559 45.0 1.0 no 4019 chrVII_250131r 12475 essential YGL137W 65 - AAACCCATGGCTCAGTAGGA V|28|L V|28|I W|27|C W|27|* SEC27 SECretory 889.0 0 0 0 0 -1.211282953045626 P41811 0.9539830088615416 0.9574310183525084 0.8858469724655151 0.51264888048172 1.0 0.0 0.0142000000923872 0.1703999936580658 3.3343999385833736 51.279689228173936 50.0 1.0 no 4020 chrVII_250390 12482 essential YGL137W 321 + ACAAAGCCTTATGTTTTATC T|108|R T|108|I P|110|A P|110|S SEC27 SECretory 889.0 0 1 0 0 0.6166498307609096 P41811 0.9476869702339172 0.9472420215606691 0.9562489986419678 0.9498909711837769 0.08832281082868576 0.007957686670124529 0.0254100114107132 0.08267473429441452 0.5504000186920166 0.21299999952316284 2.14520001411438 3.541599988937378 40.75726930501685 30.0 1.0 no 4021 chrVII_250409r 12483 essential YGL137W 343 - GACTGTCAAATCATCACTGC V|121|L V|121|I L|119|F silent|TTG>TTA|L|119 SEC27 SECretory 889.0 0 0 0 0 -0.5137585062401768 P41811 0.9539830088615416 0.9574310183525084 0.9587849974632264 0.016699813306331638 1.0 0.02235735021531582 1.0626000165939329 0.4815999865531922 0.07119999825954437 44.97453283880873 45.0 1.0 no 4022 chrVII_250424 12484 essential YGL137W 355 + TGACAGTCAAACTATGGAAT T|120|R T|120|I SEC27 SECretory 889.0 0 0 0 0 -0.37955150705677626 P41811 0.9476869702339172 0.9472420215606691 0.1934592574834824 0.429610937833786 -0.4702000021934509 3.808000087738037 38.10055995895897 35.0 1.0 no 4023 chrVII_250500 12486 essential YGL137W 431 + GTGCGTCGCATTCAATCCAA C|145|W silent|TGC>TGT|C|145 silent|GTC>GTG|V|146 silent|GTC>GTT|V|146 SEC27 SECretory 889.0 0 0 0 0 0.3020359952238217 P41811 0.9286419749259948 0.0568520724773407 9.922200202941896 51.541752757169654 50.0 1.0 no 4024 chrVII_250591 12489 essential YGL137W 522 + CCAAATTTCACGTTAACCAC P|175|R P|175|L SEC27 SECretory 889.0 0 0 0 0 0.7278893926414348 P41811 0.9432820081710817 0.9430609941482544 0.00706678070127964 0.014657639898359776 4.729599952697754 4.886000156402588 42.80317819487141 40.0 1.0 no 4025 chrVII_250663r 12490 essential YGL137W 597 - TCCGACGCAGTAATCATATA silent|TCG>TCC|S|205 silent|TCG>TCA|S|205 D|206|H D|206|N SEC27 SECretory 889.0 0 0 0 0 -0.9939057229387104 P41811 0.9486550092697144 0.956179976463318 0.005841644946485758 0.02030763402581215 0.5375999808311462 0.16019999980926514 44.811114436863186 40.0 1.0 no 4026 chrVII_250686 12493 essential YGL137W 617 + CGACTTAACCATCAAAATTT D|207|E silent|GAC>GAT|D|207 SEC27 SECretory 889.0 0 0 0 0 0.6888840502199525 P41811 0.9532920122146606 0.0 2.7374000549316406 37.05019317018883 30.0 1.0 no 4027 chrVII_250713r 12494 essential YGL137W 647 - TGGCTACACATGACTTCGTT A|222|P A|222|T V|221|L V|221|I SEC27 SECretory 889.0 0 0 0 0 -0.2822290691996606 P41811 0.9573720097541808 0.9523990154266356 0.9539830088615416 0.9574310183525084 0.21221481263637546 0.3740147948265076 0.16522985696792605 0.49893057346344 5.01800012588501 2.024199962615967 -0.11140000075101852 -0.4778000116348266 48.78100967436296 45.0 1.0 no 4028 chrVII_250723 12495 essential YGL137W 654 + TCATGTGTAGCCACTCTAGA S|219|* S|219|L SEC27 SECretory 889.0 0 0 0 0 -0.7476763309440837 P41811 0.9298099875450134 0.09050340950489044 0.6308000087738037 51.136745929144865 45.0 1.0 no 4029 chrVII_250841r 12497 essential YGL137W 775 - AGTCTTTTCTACCTTGTAAG K|264|N silent|AAG>AAA|K|264 SEC27 SECretory 889.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.0009234513870830797 P41811 0.9355990290641784 0.9818009734153748 0.8772000074386597 44.51882034210661 35.0 1.0 no 4030 chrVII_250984 12501 essential YGL137W 915 + ACTTTATCACTTGACCCTGT T|306|S T|306|I SEC27 SECretory 889.0 0 0 0 0 0.2149336145251496 P41811 0.9491789937019348 0.9472420215606691 0.15219752490520475 0.4418959617614746 1.3982000350952148 1.954599976539612 50.02501377383993 40.0 1.0 no 4031 chrVII_250998r 12502 essential YGL137W 932 - ACCATACTAGCTTACCGACA W|317|S W|317|* W|317|C W|317|* SEC27 SECretory 889.0 0 0 0 0 -0.6311190905794648 P41811 0.8858469724655151 0.8858469724655151 0.002954369178041816 0.04923965036869049 3.6387999057769775 3.034199953079224 49.445857445702536 45.0 1.0 no 4032 chrVII_251098r 12504 essential YGL137W 1032 - TCCTTAGTTTGTAAAGATAA K|350|N silent|AAG>AAA|K|350 E|351|Q E|351|K SEC27 SECretory 889.0 1 Series([], Name: modification, dtype: object) 0 0 0 1.1090424046630878 P41811 0.9355990290641784 0.956179976463318 0.9475290179252625 0.004312396049499512 0.02751144021749496 0.021334847435355183 0.3009999990463257 0.06239999830722809 -0.5451999902725221 36.841303419634755 25.0 1.0 no 4033 chrVII_251164r 12509 essential YGL137W 1098 - ACTGTAACAAACCTACCATT V|373|L V|373|I SEC27 SECretory 889.0 0 0 0 0 0.2729077604786476 P41811 0.9539830088615416 0.9574310183525084 0.009601620025932787 0.013447077013552187 0.17059999704360962 -1.3495999574661257 42.27633034630833 35.0 1.0 no 4034 chrVII_251358r 12516 essential YGL137W 1292 - TATCAATAGCAGAATGCATT D|437|H D|437|N SEC27 SECretory 889.0 0 0 0 0 0.8899142989745863 P41811 0.9486550092697144 0.956179976463318 0.004400361794978379 0.00781650934368372 0.11599999666213988 0.3955999910831451 38.98592183176589 30.0 1.0 no 4035 chrVII_251421 12517 essential YGL137W 1352 + CTTCGTCTATTTCTTCGATT F|452|L silent|TTC>TTT|F|452 silent|GTC>GTG|V|453 silent|GTC>GTT|V|453 SEC27 SECretory 889.0 0 0 0 0 0.3753110606930969 P41811 0.9387490153312684 0.3112702667713165 0.2223999947309494 45.57933520952122 35.0 1.0 no 4036 chrVII_251498r 12518 essential YGL137W 1432 - CATCACCAGCTCACCGTTAT silent|GTG>GTC|V|483 silent|GTG>GTA|V|483 V|483|L V|483|M SEC27 SECretory 889.0 0 0 0 0 0.3910786599819531 P41811 0.9539830088615416 0.9587630033493042 0.4499182105064392 0.1565278023481369 0.35920000076293945 -0.6128000020980835 53.78490861824515 50.0 1.0 no 4037 chrVII_251531r 12519 essential YGL137W 1465 - TGCTTCATCACCATTACTAT A|495|P A|495|T E|494|Q E|494|K SEC27 SECretory 889.0 0 0 0 0 -0.2947270004772227 P41811 0.9573720097541808 0.9523990154266356 0.956179976463318 0.9475290179252625 0.18637944757938385 1.0 -1.2181999683380127 1.9520000219345093 -0.0006000000284984707 -0.027000000700354576 46.59122290340719 35.0 1.0 no 4038 chrVII_251669 12521 essential YGL137W 1600 + AATCCATTACATCAGGCAAA S|535|C S|535|F silent|TCC>TCG|S|535 silent|TCC>TCT|S|535 SEC27 SECretory 889.0 0 0 0 0 1.1059877470284796 P41811 0.945252001285553 0.9294660091400146 0.08396487683057785 0.12408368289470673 -0.05400000140070915 -0.186599999666214 42.130962399714114 35.0 1.0 no 4039 chrVII_251768r 12526 essential YGL137W 1702 - ATACATTTCCTTTGTGTAAT M|573|I M|573|I SEC27 SECretory 889.0 0 0 0 0 0.0908089802857191 P41811 0.9553959965705872 0.9553959965705872 0.08739043772220613 0.08739043772220613 1.4174000024795532 1.4174000024795532 41.00103052779758 25.0 1.0 no 4040 chrVII_251886 12529 essential YGL137W 1817 + CCAAACATTGACTTTAAGAG Q|607|E Q|607|* T|608|R T|608|I SEC27 SECretory 889.0 0 0 0 0 0.5209286814604017 P41811 0.9590039849281312 0.9476869702339172 0.9472420215606691 0.14180350303649902 0.0039034930523484954 0.04121332243084908 37.19846602105656 35.0 1.0 no 4041 chrVII_251937r 12531 essential YGL137W 1871 - AGTCCTTACCCTCAACATTT D|630|H D|630|N K|629|N silent|AAG>AAA|K|629 SEC27 SECretory 889.0 0 1 0 0 -0.1715849892413383 P41811 0.9486550092697144 0.956179976463318 0.9355990290641784 0.030715515837073326 0.09844104945659636 0.029054619371891018 51.12913023033588 40.0 1.0 no 4042 chrVII_266524r 12545 essential YGL130W 382 - GACAAGTTCACCATCTAATA V|134|L V|134|I CEG1 Capping Enzyme Guanylyltransferase 459.0 0 0 0 0 -1.4246820776541511 Q01159 0.8208739757537842 0.8423929810523987 0.0254938155412674 0.12699294090270996 -0.8393999934196472 -0.6585999727249146 41.6260494775804 35.0 1.0 no 4043 chrVII_266595 12546 essential YGL130W 450 + TTCGATTGTCTTGCTATCAA F|151|L silent|TTC>TTT|F|151 CEG1 Capping Enzyme Guanylyltransferase 459.0 0 0 0 0 0.03780223813002796 Q01159 0.78233802318573 0.0 0.4307999908924103 44.43077755680497 35.0 1.0 no 4044 chrVII_266799 12548 essential YGL130W 654 + AAACTACCACATCTTTCTGA L|220|V silent|CTA>TTA|L|220 P|221|A P|221|S CEG1 Capping Enzyme Guanylyltransferase 459.0 0 0 0 0 0.19754312126575607 Q01159 0.9207149744033812 0.9181770086288452 0.907164990901947 0.09993494302034378 0.9343613386154176 1.0 0.4986000061035156 42.646695917355146 35.0 1.0 no 4045 chrVII_266857r 12551 essential YGL130W 715 - TAACAATGAATCTTTTCCGC L|244|F silent|TTG>TTA|L|244 CEG1 Capping Enzyme Guanylyltransferase 459.0 0 0 0 0 0.6388527433478234 Q01159 0.8656449913978577 0.20106399059295652 0.6836000084877014 40.69350309923875 35.0 1.0 no 4046 chrVII_266847r 12552 essential YGL130W 705 - TCTTTTCCGCCGGCAGTGTA D|242|H D|242|N G|240|A G|240|E CEG1 Capping Enzyme Guanylyltransferase 459.0 0 0 0 0 -2.4602398481746914 Q01159 0.8954830169677734 0.9174209833145142 0.8981860280036926 0.8883270025253296 0.0 0.0 0.2357610911130905 0.04931989312171936 59.33824029816896 55.00000000000001 1.0 yes 4047 chrVII_267075r 12558 essential YGL130W 933 - TCAAATTCCTTCCTATCGAA E|318|Q E|318|K CEG1 Capping Enzyme Guanylyltransferase 459.0 0 1 0 0 0.4659887576940639 Q01159 0.927986979484558 0.905135989189148 43.70246519725055 35.0 1.0 no 4048 chrVII_269707r 12560 essential YGL128C 415 + TCAACTTGCCCTATGGTGAC F|139|L silent|TTC>TTT|F|139 N|140|K silent|AAC>AAT|N|140 0 0 0 0 -0.5593785111731853 P52868 0.0 1.0 51.59033058077229 50.0 0.0 no 4049 chrVII_269714r 12561 essential YGL128C 408 + AAACATTTCAACTTGCCCTA H|138|D H|138|Y 0 0 0 0 0.3267444240216626 P52868 0.02657170593738556 0.2335521578788757 44.376827019530204 35.0 0.0 no 4050 chrVII_270015 12567 essential YGL128C 110 - TCCTGTATTTGCGTTTAATT R|43|T R|43|K R|43|S silent|AGG>AGA|R|43 0 0 0 0 -0.42380039425781424 P52868 0.01761433482170105 0.2716354429721832 0.014217080548405647 44.45962404673668 30.0 0.0 no 4051 chrVII_270016 12568 essential YGL128C 109 - CCTGTATTTGCGTTTAATTT R|43|T R|43|K 0 0 0 0 0.8373925285590897 P52868 0.01761433482170105 0.2716354429721832 43.751272994557674 30.0 0.0 no 4052 chrVII_270016r 12569 essential YGL128C 106 + CCCAAATTAAACGCAAATAC Q|37|E Q|37|* silent|CCC>CCG|P|36 silent|CCC>CCT|P|36 0 0 0 0 -1.0361542357260405 P52868 1.0 37.03212116762808 35.0 0.0 no 4053 chrVII_277695r 12574 essential YGL123W 81 - CCCTTTTCTTCAGTGTTTCT K|33|N silent|AAG>AAA|K|33 G|34|R G|34|R RPS2 Ribosomal Protein of the Small subunit 254.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.2117954203470878 P25443 0.16643811762332916 0.08857978135347366 0.08857978135347366 0.5376900434494019 0.08032000064849854 0.08032000064849854 54.09994184922721 40.0 1.0 no 4054 chrVII_277903r 12579 essential YGL123W 289 - AACGACAACAGCCTTAAATC V|103|L V|103|I V|102|L V|102|I RPS2 Ribosomal Protein of the Small subunit 254.0 0 0 0 0 0.3171192426170701 P25443 0.053286131471395486 0.18581826984882355 0.0555066242814064 0.012994492426514627 2.273819923400879 -1.0214400291442869 -0.4124999940395355 -0.8293399810791016 40.16565356173396 40.0 1.0 no 4055 chrVII_277934 12580 essential YGL123W 317 + CTCTAACGGTCACGTTGGTT S|107|C S|107|F N|108|K silent|AAC>AAT|N|108 RPS2 Ribosomal Protein of the Small subunit 254.0 0 0 0 0 0.4347485672472571 P25443 0.17702442407608032 0.6882963180541992 0.26593753695487976 -0.017680000513792038 -0.6546000242233276 0.7142000198364258 50.25048844442029 50.0 1.0 no 4056 chrVII_278160r 12592 essential YGL123W 546 - TGCAACAACTTTTTGACAGC L|188|F silent|TTG>TTA|L|188 L|187|F silent|TTG>TTA|L|187 RPS2 Ribosomal Protein of the Small subunit 254.0 0 1 0 0 0.4178476005046417 P25443 0.16751140356063846 0.037355970591306686 1.97160005569458 4.740260124206543 42.93804158863094 40.0 1.0 no 4057 chrVII_278132r 12593 essential YGL123W 518 - CGACGATACCAGAACCTCTT V|179|L V|179|I RPS2 Ribosomal Protein of the Small subunit 254.0 0 1 0 0 -0.8293055471499957 P25443 0.03810097649693489 0.14134114980697632 -0.8731200098991394 -0.966539978981018 48.118315648279065 50.0 1.0 no 4058 chrVII_279344r 12596 essential YGL122C 1121 + CTCTTCATTGTCGAAGATCA S|375|C S|375|F S|376|* S|376|L NAB2 Nuclear polyAdenylated RNA-Binding 525.0 0 0 0 0 0.7506339594971707 P32505 44.64533350999795 40.0 0.0 no 4059 chrVII_279348 12597 essential YGL122C 1120 - GATCTTCGACAATGAAGAGT K|379|N silent|AAG>AAA|K|379 silent|TCG>TCC|S|378 silent|TCG>TCA|S|378 NAB2 Nuclear polyAdenylated RNA-Binding 525.0 0 0 0 0 0.23052363729546904 P32505 40.7761000516698 40.0 0.0 no 4060 chrVII_279430 12598 essential YGL122C 1038 - ACTTTCGCATCTTCATTTGC V|353|L V|353|I silent|GCG>GCC|A|351 silent|GCG>GCA|A|351 NAB2 Nuclear polyAdenylated RNA-Binding 525.0 0 0 0 0 0.6906424329819771 P32505 48.856707422854974 40.0 0.0 no 4061 chrVII_279463r 12602 essential YGL122C 1002 + TCCAATCCATCATGCCCATT silent|TCC>TCG|S|335 silent|TCC>TCT|S|335 S|335|C S|335|F NAB2 Nuclear polyAdenylated RNA-Binding 525.0 0 0 0 0 1.1660990926488783 P32505 54.561135141905424 45.0 0.0 no 4062 chrVII_279643r 12605 essential YGL122C 822 + CCAAATTGTCCAAAGCCTCC P|275|R P|275|L NAB2 Nuclear polyAdenylated RNA-Binding 525.0 0 0 0 0 0.6579687033363505 P32505 0.9432820081710817 0.9430609941482544 0.8131776452064514 0.17761990427970886 0.4286479949951172 0.6168199777603149 50.7584239907452 50.0 0.0 no 4063 chrVII_279680r 12609 essential YGL122C 785 + CCCACATGCACACCCAACTA P|263|R P|263|L P|263|A P|263|S NAB2 Nuclear polyAdenylated RNA-Binding 525.0 0 0 0 0 0.12484607553141334 P32505 55.126565781103636 55.00000000000001 0.0 no 4064 chrVII_279746r 12611 essential YGL122C 719 + CTTCACTCCAACCAAGAAAG F|241|L silent|TTC>TTT|F|241 T|242|S T|242|I NAB2 Nuclear polyAdenylated RNA-Binding 525.0 0 0 0 0 0.3318272496653264 P32505 43.00534052825157 45.0 0.0 no 4065 chrVII_279735 12612 essential YGL122C 733 - TCTGCAACGCCCCTCTTTCT R|251|T R|251|K C|250|S C|250|Y NAB2 Nuclear polyAdenylated RNA-Binding 525.0 0 1 0 0 -0.20327412057150213 P32505 59.67610983506735 55.00000000000001 0.0 no 4066 chrVII_279790 12615 essential YGL122C 678 - ATTCCAAGTGCTTTTGCTAA G|232|A G|232|E G|232|R G|232|R NAB2 Nuclear polyAdenylated RNA-Binding 525.0 0 0 0 0 -0.3474384329432944 P32505 46.327071446753386 35.0 0.0 no 4067 chrVII_279864 12619 essential YGL122C 604 - ACCTCTACGATTCTTTCCAA G|208|R G|208|S G|208|A G|208|D NAB2 Nuclear polyAdenylated RNA-Binding 525.0 0 0 0 0 -1.1340772294408783 P32505 48.53343881047306 40.0 0.0 no 4068 chrVII_279921 12623 essential YGL122C 547 - ATCTACAGGCGCAAACTGAG D|189|H D|189|N V|188|L V|188|I NAB2 Nuclear polyAdenylated RNA-Binding 525.0 0 0 0 0 0.05732126818645511 P32505 0.9539830088615416 0.9574310183525084 1.0 0.6269380450248718 45.956327725204744 50.0 0.0 no 4069 chrVII_280015 12630 essential YGL122C 453 - GCATTCTGGGTCCCTAGTTG A|158|P A|158|T Q|156|H silent|CAG>CAA|Q|156 NAB2 Nuclear polyAdenylated RNA-Binding 525.0 0 0 0 0 -0.07369323257664609 P32505 58.15820741270068 55.00000000000001 0.0 no 4070 chrVII_280236 12634 essential YGL122C 268 - CGCATTCATCATTCTAATTT A|96|P A|96|T M|94|I M|94|I NAB2 Nuclear polyAdenylated RNA-Binding 525.0 0 0 0 0 -0.3124129628547017 P32505 0.9573720097541808 0.9523990154266356 0.9553959965705872 0.9553959965705872 0.27672094106674194 0.6433203816413879 0.3734448850154877 0.3734448850154877 2.392620086669922 0.3677600026130676 0.3721399903297424 0.3721399903297424 1.7634600400924685 0.36976000666618347 0.2832399904727936 0.2832399904727936 41.81235545485572 30.0 0.0 no 4071 chrVII_280396r 12637 essential YGL122C 105 + GTCTTATTGATCGTTAACGG silent|GTC>GTG|V|36 silent|GTC>GTT|V|36 NAB2 Nuclear polyAdenylated RNA-Binding 525.0 0 0 0 0 -0.2133420610965676 P32505 42.758005050762506 40.0 0.0 no 4072 chrVII_282343r 12643 essential YGL120C 1572 + ATGCTAGCGGTGATGTTAAT L|526|V silent|CTA>TTA|L|526 PRP43 Pre-mRNA Processing 767.0 0 0 0 0 -0.4703814638379002 P53131 0.9512209892272948 0.015175646170973778 2.3366000652313232 45.891908796604405 40.0 0.0 no 4073 chrVII_282355 12644 essential YGL120C 1563 - ACCGCTAGCATAGGATCCAA silent|GCG>GCC|A|527 silent|GCG>GCA|A|527 V|528|L V|528|M PRP43 Pre-mRNA Processing 767.0 0 0 0 0 0.5406383125669818 P53131 0.9539830088615416 0.9587630033493042 0.012223930098116398 0.004046869464218617 1.674399971961975 -0.1225999966263771 51.9959872019287 50.0 0.0 no 4074 chrVII_282479r 12649 essential YGL120C 1436 + TTTCGATTTTATGGATCCAC F|480|L silent|TTC>TTT|F|480 PRP43 Pre-mRNA Processing 767.0 0 0 0 0 0.2310638269887087 P53131 0.9387490153312684 0.0 1.9299999475479128 43.594476137578404 35.0 0.0 no 4075 chrVII_282520r 12651 essential YGL120C 1395 + GTTCTAGAACTAAAAAAATT L|467|V silent|CTA>TTA|L|467 PRP43 Pre-mRNA Processing 767.0 0 0 0 0 -0.11493823397316585 P53131 0.9512209892272948 0.0036163046024739742 2.6614000797271733 28.66441452737985 20.0 0.0 no 4076 chrVII_282683r 12660 essential YGL120C 1232 + ACTTGTTTCCCCTATCTCCA L|412|V L|412|F PRP43 Pre-mRNA Processing 767.0 0 1 0 0 1.3554534977662045 P53131 0.9512209892272948 0.9587849974632264 0.8308120965957642 0.027987832203507423 -0.598800003528595 0.19380000233650208 57.717524002482044 45.0 0.0 no 4077 chrVII_282841r 12663 essential YGL120C 1074 + CCTGCTCCAGAGTCACATAA P|359|R P|359|L A|360|G A|360|V PRP43 Pre-mRNA Processing 767.0 0 0 0 0 -1.4094468228875563 P53131 0.9432820081710817 0.9430609941482544 0.9484469890594482 0.9504740238189696 0.002067818073555827 0.0015578658785670994 0.19902366399765012 0.05415971204638481 0.7098000049591064 0.8108000159263611 1.0335999727249146 3.4932000637054443 52.3549931830151 50.0 0.0 no 4078 chrVII_283086r 12668 essential YGL120C 829 + ACTATACACCGGAATTTCAA Y|277|* silent|TAC>TAT|Y|277 T|279|R T|279|I PRP43 Pre-mRNA Processing 767.0 0 0 0 0 -0.8488029504937957 P53131 0.9476869702339172 0.9472420215606691 0.0014388550771400332 0.0016037567984312773 -0.5663999915122986 -0.39660000801086426 41.33880729260893 35.0 0.0 no 4079 chrVII_283114 12670 essential YGL120C 804 - TCAACTGGATATGTTCTGCC E|275|Q E|275|K V|274|L V|274|I PRP43 Pre-mRNA Processing 767.0 0 0 0 0 0.6928602298371787 P53131 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.056837547570467 0.017478663474321362 0.0 0.0 0.0689999982714653 -0.3100000023841858 2.262399911880493 -0.9164000153541564 48.44699856192978 45.0 0.0 no 4080 chrVII_283133r 12672 essential YGL120C 782 + TGCTCCATTACTTGCCGTTC A|262|G A|262|V P|263|A P|263|S PRP43 Pre-mRNA Processing 767.0 0 0 0 0 0.09947772649938152 P53131 0.9484469890594482 0.9504740238189696 0.9562489986419678 0.9498909711837769 0.04922257736325264 0.004739112686365843 0.01060344837605953 0.0787239819765091 1.7103999853134155 1.5484000444412231 1.8860000371932983 2.388799905776977 55.5817027732835 50.0 0.0 no 4081 chrVII_283151 12673 essential YGL120C 767 - GAGCATCGTTGAAGTAGCGT A|262|P A|262|T D|261|H D|261|N PRP43 Pre-mRNA Processing 767.0 0 0 0 0 0.3927075836431199 P53131 0.9573720097541808 0.9523990154266356 0.9486550092697144 0.956179976463318 0.007217959500849247 0.004953891504555941 0.10378486663103104 0.5613007545471191 3.974400043487549 3.2033998966217037 -0.243599995970726 -0.49020001292228704 49.676978876957655 50.0 0.0 no 4082 chrVII_283253r 12674 essential YGL120C 662 + ACTAGCTACTGATATTTTGA L|222|V silent|CTA>TTA|L|222 A|223|G A|223|V PRP43 Pre-mRNA Processing 767.0 0 0 0 0 0.8798783216075414 P53131 0.9512209892272948 0.9484469890594482 0.9504740238189696 0.1816623955965042 0.5365666151046753 0.16610689461231232 2.12940001487732 1.0393999814987185 1.6044000387191772 40.69193152590964 30.0 0.0 no 4083 chrVII_283636 12680 essential YGL120C 282 - TCATCTCTCTGGGCATGTAC E|101|Q E|101|K D|100|H D|100|N PRP43 Pre-mRNA Processing 767.0 0 0 0 0 -1.7741940191849503 P53131 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.4121444523334503 0.3023281693458557 0.0046706218272447595 0.008476480841636658 0.3267999887466431 0.45480000972747797 1.680999994277954 0.5249999761581421 52.83504818387041 50.0 0.0 no 4084 chrVII_283784r 12683 essential YGL120C 131 + TCATGATGCTGGTGAATTCA H|45|D H|45|Y PRP43 Pre-mRNA Processing 767.0 0 0 0 0 0.02917275643374978 P53131 0.9473130106925964 0.9489949941635132 0.6368981599807739 0.11660505831241608 1.4766000509262085 -0.17219999432563782 45.34633556192381 40.0 0.0 no 4085 chrVII_283795r 12685 essential YGL120C 120 + CCACTTGTCCATCATGATGC L|42|V L|42|F P|41|R P|41|L PRP43 Pre-mRNA Processing 767.0 0 1 0 0 -0.4207678671710913 P53131 0.9512209892272948 0.9587849974632264 0.9432820081710817 0.9430609941482544 0.602182924747467 0.7111380696296692 0.5327060818672179 0.2962259650230408 1.146399974822998 5.340400218963623 0.5709999799728394 1.0232000350952148 52.74073522500714 50.0 0.0 no 4086 chrVII_290022 12691 essential YGL116W 213 + TCAAGACCTAAGATTACAAT S|72|* S|72|L P|74|A P|74|S 0 0 0 0 -0.30688157985022363 P26309 0.2755654454231262 1.0 0.6922463774681091 36.98795846428493 30.0 1.0 no 4087 chrVII_290323 12696 essential YGL116W 514 + CGTCGCCAATTTCACACTTA S|173|W S|173|L P|174|A P|174|S 0 0 0 0 0.6190881247708165 P26309 0.005735392216593027 0.11221709847450256 0.2842206954956055 0.18345406651496887 48.734865842167146 45.0 1.0 no 4088 chrVII_290483 12700 essential YGL116W 674 + AACACATTATAGTTATCAGC T|226|R T|226|I H|227|D H|227|Y 0 0 0 0 0.7221659110424604 P26309 0.5161076188087463 0.16085168719291687 0.5439831614494324 0.9914685487747192 38.485332049204935 30.0 1.0 no 4089 chrVII_290713r 12704 essential YGL116W 907 - CCACGTAACGCTGCATATTG silent|ACG>ACC|T|308 silent|ACG>ACA|T|308 W|309|S W|309|* 0 0 0 0 -1.3886225107495584 P26309 0.0022880698088556532 47.95804834928936 50.0 1.0 no 4090 chrVII_291123 12716 essential YGL116W 1314 + TCGCCAAATATTCTAGCCTC P|440|A P|440|S S|439|W S|439|L 0 0 0 0 -0.12286953879358993 P26309 0.771185576915741 0.7745007276535034 0.08428221195936203 0.5868852734565735 49.31229785729681 45.0 1.0 no 4091 chrVII_291126 12719 essential YGL116W 1317 + CCAAATATTCTAGCCTCTGG P|440|R P|440|L 0 0 0 0 0.4713775775967498 P26309 0.5359823107719421 0.3313347399234772 47.75261084515183 45.0 1.0 no 4092 chrVII_292143 12722 high_effect YGL115W 110 + TTCTTACCGTTTAATTGTCT S|38|C S|38|F Y|39|* silent|TAC>TAT|Y|39 SNF4 Sucrose NonFermenting 322.0 0 0 0 0 0.277423511570142 P12904 0.9879119992256165 0.9685909748077391 0.0 0.0 0.3441999852657318 -0.12031999975442885 0.11271999776363373 1.0332000255584717 44.06098457336713 30.0 1.0 no 4093 chrVII_292214 12723 high_effect YGL115W 181 + GCATTGTCTCTGCGCCATTA S|61|R silent|AGC>AGT|S|61 SNF4 Sucrose NonFermenting 322.0 0 0 0 0 0.6576640264770695 P12904 0.9487490057945251 0.006183996330946685 -1.2331000566482544 56.124957024512746 50.0 1.0 no 4094 chrVII_292315r 12726 high_effect YGL115W 285 - TCTACTAATTCGAACTTATC D|102|H D|102|N V|101|L V|101|I SNF4 Sucrose NonFermenting 322.0 0 0 0 0 0.7166991773873718 P12904 0.965224027633667 0.97645902633667 0.9693499803543092 0.9770190119743348 0.004295089282095432 0.007676764391362667 0.34363657236099243 0.6842683553695679 0.07744000107049942 -0.06375999748706818 -1.3540600538253784 0.25154000520706177 36.939662903445246 30.0 1.0 no 4095 chrVII_292413 12728 high_effect YGL115W 380 + TCCTTCTAGACCCTTATTTG P|128|R P|128|L P|128|A P|128|S SNF4 Sucrose NonFermenting 322.0 0 0 0 0 -0.5832231816438019 P12904 0.9074479937553406 0.9137349724769592 0.9314339756965636 0.9229540228843688 0.0 0.0 0.0 0.0 2.6985199451446533 2.094480037689209 3.3910601139068604 4.8441200256347665 10.073047637939453 2.3363959789276123 3.430001974105835 4.192516803741455 49.896362495159856 40.0 1.0 no 4096 chrVII_292548 12730 high_effect YGL115W 515 + GTTCGTTGCTTTAAATTGCA F|173|L silent|TTC>TTT|F|173 SNF4 Sucrose NonFermenting 322.0 0 1 0 0 0.19908125468141505 P12904 0.9824680089950562 0.0 1.6444200277328491 0.044978000223636634 44.61321691213801 35.0 1.0 no 4097 chrVII_292632 12731 high_effect YGL115W 599 + AAGCTGTCAAATGACCACTC S|201|R silent|AGC>AGT|S|201 SNF4 Sucrose NonFermenting 322.0 0 0 0 0 0.3653158454717083 P12904 0.9391239881515504 0.05705743283033371 -0.8593800067901611 45.04632802375557 45.0 1.0 no 4098 chrVII_296174 12740 essential YGL113W 242 + CAGCTTACCAGAAAGGCGTA S|82|R silent|AGC>AGT|S|82 0 0 0 0 -0.1246572343637905 P53135 0.5235376954078674 48.70991781197523 50.0 1.0 no 4099 chrVII_296231 12741 essential YGL113W 299 + GCGTGAAACGTTAAAAACAT R|101|G R|101|C 0 0 0 0 -1.3811602812099515 P53135 0.43355172872543335 0.09232369065284728 35.989622107447026 35.0 1.0 no 4100 chrVII_296181r 12742 essential YGL113W 252 - ACAACTTCCGTACGCCTTTC V|91|L V|91|I V|90|L V|90|I 0 0 0 0 0.3737946801616709 P53135 0.4720055460929871 0.4344920516014099 1.0 0.7502056360244751 52.045937302027596 50.0 1.0 no 4101 chrVII_296298r 12743 essential YGL113W 369 - TCAAGCTTACACGAGCCCTT E|130|Q E|130|K K|128|N silent|AAG>AAA|K|128 0 0 0 0 -0.3756267039828495 P53135 0.4645199775695801 0.56056809425354 0.5900568962097168 52.97902147749056 50.0 1.0 no 4102 chrVII_296399r 12747 essential YGL113W 470 - TACTTTCTATGTACTCTTTA S|163|T S|163|N E|162|Q E|162|K 0 0 0 0 0.14668240907756802 P53135 1.0 0.5541225671768188 0.0 0.0 0.6275799870491028 0.7923600077629089 1.9265799522399905 1.66211998462677 40.37540488720134 25.0 1.0 no 4103 chrVII_296504r 12751 essential YGL113W 575 - TGTCACTTCCGTACTTGGTT D|198|H D|198|N S|197|T S|197|N 0 0 0 0 0.4069181916033698 P53135 0.01573738269507885 0.03799309581518173 0.2541041970252991 0.2329340428113937 1.6102999448776243 1.5754799842834473 -0.10307999700307846 0.0036800000816583633 52.64802727411444 45.0 1.0 no 4104 chrVII_297211r 12762 essential YGL113W 1282 - GCTATCGTTGACCTTTTTCA S|434|T S|434|N D|433|H D|433|N 1 Series([], Name: modification, dtype: object) 0 0 0 0.7132579157772917 P53135 0.803106963634491 0.5724865198135376 0.3624159395694733 0.5501783490180969 49.89307120827056 40.0 1.0 no 4105 chrVII_297325 12767 essential YGL113W 1393 + CATCTTCACCCGCATTGAGA S|466|C S|466|F S|467|* S|467|L 1 Series([], Name: modification, dtype: object) 0 0 0 0.11630065915924735 P53135 0.0 0.0 0.058869071304798126 52.62616577725152 50.0 1.0 no 4106 chrVII_297326 12769 essential YGL113W 1394 + ATCTTCACCCGCATTGAGAA S|466|C S|466|F S|467|* S|467|L 1 Series([], Name: modification, dtype: object) 0 0 0 0.1383455829070929 P53135 0.0 0.0 0.058869071304798126 49.82394019632363 45.0 1.0 no 4107 chrVII_297334r 12771 essential YGL113W 1405 - AGCGTCCACCCTTCTCAATG A|475|P A|475|T D|474|H D|474|N 0 1 0 0 -0.13207996381512013 P53135 0.3217867016792297 0.21162697672843933 0.17507076263427734 0.5847388505935669 56.19635385869913 55.00000000000001 1.0 no 4108 chrVII_298658 12780 essential YGL112C 1051 - TACATAGTCCAACAAAGATG V|357|L V|357|I TAF6 TATA binding protein-Associated Factor 516.0 0 0 0 0 0.5092917592341666 P53040 0.9539830088615416 0.9574310183525084 0.04907411336898804 1.0 37.48008064136536 35.0 0.0 no 4109 chrVII_298816r 12785 essential YGL112C 890 + AAGCAATACTTCTATTTTCC S|298|R silent|AGC>AGT|S|298 TAF6 TATA binding protein-Associated Factor 516.0 0 0 0 0 0.7508333311974067 P53040 0.9417110085487366 0.4628501236438751 41.03165233989779 30.0 0.0 no 4110 chrVII_298950r 12787 essential YGL112C 756 + ACTTCACTACGAACTGATAG T|253|S T|253|I S|254|* S|254|L TAF6 TATA binding protein-Associated Factor 516.0 0 0 0 0 -1.2091473891547548 P53040 0.9491789937019348 0.9472420215606691 0.9298099875450134 1.0 0.0431080162525177 0.005764152854681015 40.26023996231049 40.0 0.0 no 4111 chrVII_299009 12788 essential YGL112C 700 - AGCTTGACTCTTCGCTGTCA A|240|P A|240|T TAF6 TATA binding protein-Associated Factor 516.0 0 0 0 0 -0.27043148668709904 P53040 0.9573720097541808 0.9523990154266356 0.06312339007854463 0.6258140206336975 54.6676057206614 50.0 0.0 no 4112 chrVII_299300r 12794 essential YGL112C 406 + CACATTGGCTAGCAGTTGAA H|137|D H|137|Y TAF6 TATA binding protein-Associated Factor 516.0 0 0 0 0 -0.25262842060617363 P53040 0.9473130106925964 0.9489949941635132 0.0 0.0 47.45163867496114 45.0 0.0 no 4113 chrVII_299380 12796 essential YGL112C 329 - AATCTACTTCTTCCTCATCC D|116|H D|116|N V|115|L V|115|I TAF6 TATA binding protein-Associated Factor 516.0 0 0 0 0 0.1590022541056023 P53040 0.9486550092697144 0.956179976463318 0.9539830088615416 0.9574310183525084 0.004082533065229654 0.012339106760919094 0.035570792853832245 0.15648983418941498 49.513578059109705 40.0 0.0 no 4114 chrVII_299491 12801 essential YGL112C 218 - GTTCCACATTCAGAACACGC E|79|Q E|79|K silent|GTG>GTC|V|78 silent|GTG>GTA|V|78 TAF6 TATA binding protein-Associated Factor 516.0 0 0 0 0 0.3641871477570636 P53040 0.956179976463318 0.9475290179252625 0.0 0.0 49.18652124642955 50.0 0.0 no 4115 chrVII_299515r 12802 essential YGL112C 191 + AACTACAGACGATGTATCGA T|65|S T|65|I T|66|R T|66|I TAF6 TATA binding protein-Associated Factor 516.0 0 0 0 0 -0.38653485352586814 P53040 0.9491789937019348 0.9472420215606691 0.9476869702339172 0.9472420215606691 0.318965345621109 0.013053770177066326 0.02207125723361969 0.020322350785136226 0.4972259998321533 0.768992006778717 0.576475977897644 0.6020539999008179 40.9593113889942 40.0 0.0 no 4116 chrVII_299578 12803 essential YGL112C 131 - GTTCAATAATCTCTAGAATA E|50|Q E|50|K TAF6 TATA binding protein-Associated Factor 516.0 0 0 0 0 -0.5995404210294019 P53040 0.956179976463318 0.9475290179252625 0.09445524215698242 0.014107456430792809 -0.4878619909286499 -0.9227359890937804 34.859842691121344 25.0 0.0 no 4117 chrVII_299696r 12805 essential YGL112C 10 + AGCAGCAATCTTACACAATT Q|5|E Q|5|* Q|6|E Q|6|* TAF6 TATA binding protein-Associated Factor 516.0 0 0 0 0 -1.6320653297359289 P53040 0.9590039849281312 0.9590039849281312 42.5448194248811 35.0 0.0 no 4118 chrVII_300096r 12809 essential YGL111W 121 - AACGTAAGCTTTCAATCCTT V|47|L V|47|I NSA1 Nop Seven Associated 463.0 0 0 0 0 -0.1215218842463113 P53136 0.1248846799135208 0.94704669713974 43.61045944771786 35.0 1.0 no 4119 chrVII_300108 12810 essential YGL111W 130 + AAGCTTACGTTGACAGGATG A|45|G A|45|V NSA1 Nop Seven Associated 463.0 0 0 0 0 -1.6697326569045727 P53136 0.6481005549430847 0.17837771773338318 44.0421610681193 45.0 1.0 no 4120 chrVII_300150 12812 essential YGL111W 172 + CCATCTTAGCAAGGAATTCA silent|GCC>GCG|A|58 silent|GCC>GCT|A|58 I|59|M silent|ATC>ATT|I|59 NSA1 Nop Seven Associated 463.0 0 0 0 0 -0.9953146296484928 P53136 0.02753186598420143 45.0815246449676 40.0 1.0 no 4121 chrVII_300149 12813 essential YGL111W 171 + GCCATCTTAGCAAGGAATTC silent|GCC>GCG|A|58 silent|GCC>GCT|A|58 A|58|G A|58|V NSA1 Nop Seven Associated 463.0 0 0 0 0 -0.06626123087775126 P53136 0.1893981546163559 0.3753177523612976 47.43818519911451 45.0 1.0 no 4122 chrVII_300150r 12814 essential YGL111W 175 - CCCTGAATTCCTTGCTAAGA G|65|R G|65|R G|65|A G|65|E NSA1 Nop Seven Associated 463.0 0 0 0 0 -1.2991377908307071 P53136 0.0 0.0 0.0 0.0 49.91842065028714 45.0 1.0 no 4123 chrVII_300218 12816 essential YGL111W 240 + GCTCTCCAGGTCGATCCCAA L|82|V L|82|F A|81|G A|81|V NSA1 Nop Seven Associated 463.0 0 0 0 0 -0.8001644675560007 P53136 60.24478674739197 60.0 1.0 no 4124 chrVII_300325r 12820 essential YGL111W 350 - CCAATTTGGCATCATCAAAA L|123|F silent|TTG>TTA|L|123 NSA1 Nop Seven Associated 463.0 0 0 0 0 0.08436072764439806 P53136 0.044275425374507904 41.10763552548599 35.0 1.0 no 4125 chrVII_300339r 12821 essential YGL111W 364 - ACTTGAAAGTGATTCCAATT S|128|T S|128|N NSA1 Nop Seven Associated 463.0 0 0 0 0 0.11296138667521395 P53136 0.4314214885234833 0.3722802996635437 39.08909678787995 30.0 1.0 no 4126 chrVII_300378r 12822 essential YGL111W 403 - GACAAAACCATCCACCAACT V|141|L V|141|I NSA1 Nop Seven Associated 463.0 0 0 0 0 0.23799896248692395 P53136 0.04151668027043343 0.2880095839500427 45.5644049351107 45.0 1.0 no 4127 chrVII_300439 12823 essential YGL111W 461 + ATTCGTAGCTGCTACCAAAT F|155|L silent|TTC>TTT|F|155 NSA1 Nop Seven Associated 463.0 0 0 0 0 1.114457272555386 P53136 0.5211749076843262 46.57636451044016 40.0 1.0 no 4128 chrVII_300440 12824 essential YGL111W 462 + TTCGTAGCTGCTACCAAATC F|155|L silent|TTC>TTT|F|155 NSA1 Nop Seven Associated 463.0 0 0 0 0 0.5549844923814968 P53136 0.5211749076843262 47.58374891479672 45.0 1.0 no 4129 chrVII_300400 12825 essential YGL111W 422 + CACATTATGTCCCATAAAAA T|142|R T|142|I NSA1 Nop Seven Associated 463.0 0 0 0 0 -0.15109195919639734 P53136 0.4803667664527893 0.1765032857656479 38.567704063051046 30.0 1.0 no 4130 chrVII_300516r 12826 essential YGL111W 541 - TACTGGTGCTTTCAGTCCAA V|187|L V|187|I NSA1 Nop Seven Associated 463.0 0 0 0 0 -0.04807158097971058 P53136 1.0 0.11986088007688522 51.66665140389017 45.0 1.0 no 4131 chrVII_300646 12828 essential YGL111W 668 + CCAATCTTTAAAGCAAATTT Q|224|E Q|224|* S|225|C S|225|F NSA1 Nop Seven Associated 463.0 0 0 0 0 0.6057028131717248 P53136 1.0 0.04257702827453613 0.04039960354566574 36.012484144850134 25.0 1.0 no 4132 chrVII_300646r 12830 essential YGL111W 671 - CCCAAATTTGCTTTAAAGAT W|230|S W|230|* W|230|C W|230|* NSA1 Nop Seven Associated 463.0 0 0 0 0 -1.1475472146424663 P53136 0.0 0.0 39.887831695714794 30.0 1.0 no 4133 chrVII_300815 12833 essential YGL111W 837 + ACCAAATACAGCACACAACA silent|ACC>ACG|T|280 silent|ACC>ACT|T|280 T|280|S T|280|I NSA1 Nop Seven Associated 463.0 0 0 0 0 0.9097129463412132 P53136 0.8281421661376953 0.4315218627452849 42.049378340173575 40.0 1.0 no 4134 chrVII_300957r 12834 essential YGL111W 982 - AATCACATTCAGTTCATTAA silent|GTG>GTC|V|333 silent|GTG>GTA|V|333 V|333|L V|333|M NSA1 Nop Seven Associated 463.0 0 0 0 0 0.7859205986098105 P53136 0.6958968639373779 0.12281157076358795 37.54219312445042 25.0 1.0 no 4135 chrVII_314754 12836 essential YGL099W 123 + GCCATCGAGTATTTACCTGA silent|GCC>GCG|A|42 silent|GCC>GCT|A|42 A|42|G A|42|V LSG1 Large-Subunit Gtpase 640.0 0 0 0 0 0.18878224566596624 P53145 0.15446984767913818 0.07560980319976808 50.65476728809392 45.0 1.0 no 4136 chrVII_314794r 12840 essential YGL099W 166 - CCAGTTGGCCTCATGCTTAT W|62|S W|62|* LSG1 Large-Subunit Gtpase 640.0 0 0 0 0 0.2890644005468777 P53145 0.5737438201904297 56.63628097496229 50.0 1.0 no 4137 chrVII_315039r 12844 essential YGL099W 411 - TCGTTCCATTCAGGCCTCCT E|144|Q E|144|K W|142|C W|142|* LSG1 Large-Subunit Gtpase 640.0 0 0 0 0 -0.5879752626389001 P53145 0.3039761483669281 1.0 0.0 61.575753620763074 55.00000000000001 1.0 no 4138 chrVII_315048r 12845 essential YGL099W 420 - GACATGCCCTCGTTCCATTC M|146|I M|146|I G|145|A G|145|D LSG1 Large-Subunit Gtpase 640.0 0 0 0 0 -0.4148265009993892 P53145 0.022127959877252582 0.022127959877252582 0.5963701009750366 0.475408285856247 57.53279132601779 55.00000000000001 1.0 no 4139 chrVII_315184 12848 essential YGL099W 553 + TCGAAGTTTGGAAACAGTTA I|185|M silent|ATC>ATT|I|185 LSG1 Large-Subunit Gtpase 640.0 0 0 0 0 0.1507980411694726 P53145 0.016192976385354996 39.0635837146001 35.0 1.0 no 4140 chrVII_315603 12853 essential YGL099W 972 + CCTTTATTGCCACCTCTGCC P|325|R P|325|L LSG1 Large-Subunit Gtpase 640.0 0 0 0 0 0.054775735872502784 P53145 0.5116024017333984 0.3204270899295807 59.924828900242176 55.00000000000001 1.0 no 4141 chrVII_315627 12854 essential YGL099W 996 + CAACCTCCACTGATTAATAT P|334|A P|334|S P|334|R P|334|L LSG1 Large-Subunit Gtpase 640.0 0 0 0 0 -0.3848071159482824 P53145 0.696358323097229 0.6031374931335449 0.4562882483005524 0.2809437215328217 42.511719937298665 35.0 1.0 no 4142 chrVII_315630r 12855 essential YGL099W 1002 - AAACCAATATTAATCAGTGG G|340|A G|340|D G|340|R G|340|S LSG1 Large-Subunit Gtpase 640.0 0 0 0 0 -0.5324181769924636 P53145 0.03960887342691422 0.04256024956703186 0.010698990896344185 0.0375346839427948 35.89215672940515 30.0 1.0 no 4143 chrVII_315633r 12857 essential YGL099W 1005 - ACCAAACCAATATTAATCAG L|341|F silent|TTG>TTA|L|341 V|342|L V|342|I LSG1 Large-Subunit Gtpase 640.0 0 0 0 0 -0.5549239785455866 P53145 0.11836861819028854 0.10572514683008194 0.03674603998661041 36.81250624622385 30.0 1.0 no 4144 chrVII_315947 12864 essential YGL099W 1316 + CCATATTCAAACCAAATCAA H|440|D H|440|Y LSG1 Large-Subunit Gtpase 640.0 0 0 0 0 0.5971733978268611 P53145 0.4997873604297638 0.03454725816845894 37.70447150993721 30.0 1.0 no 4145 chrVII_316024r 12872 essential YGL099W 1396 - AGTCATATAACCACGAGCTC M|471|I M|471|I LSG1 Large-Subunit Gtpase 640.0 0 0 0 0 0.8461433645701328 P53145 0.4980328381061554 0.4980328381061554 46.46487622943914 45.0 1.0 no 4146 chrVII_317575r 12877 essential YGL098W 236 - TTCTTGTTTTTGAACTGCTT R|85|T R|85|K USE1 Unconventional SNARE in the ER 245.0 0 0 0 0 -0.5109613612535252 P53146 0.932735025882721 0.955805003643036 0.0 0.0 43.74981762202629 30.0 1.0 no 4147 chrVII_317791r 12884 essential YGL098W 452 - AATCCTGTTGCAACGTGTCC D|157|H D|157|N Q|156|H silent|CAG>CAA|Q|156 USE1 Unconventional SNARE in the ER 245.0 0 0 0 0 0.09308455364285134 P53146 0.9486550092697144 0.956179976463318 0.9570760130882264 0.07293854653835298 0.868543803691864 0.09826747328042984 51.899652530667936 50.0 1.0 no 4148 chrVII_321913 12888 essential YGL097W 131 + ACCATTGGATATATTTTGCT P|45|R P|45|L P|45|A P|45|S SRM1 Suppressor of Receptor Mutations 482.0 0 0 0 0 -0.08157542361546201 P21827 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.7721137404441833 0.20178048312664032 0.3366554081439972 0.3217146396636963 2.1239490509033203 2.835569143295288 1.5940276384353638 2.1560769081115723 43.8201229411181 30.0 1.0 no 4149 chrVII_321943 12891 essential YGL097W 161 + TTCTATGTGTGAGCTTGGGT S|55|C S|55|F SRM1 Suppressor of Receptor Mutations 482.0 0 0 0 0 -0.8524777669683282 P21827 0.945252001285553 0.9294660091400146 0.018235452473163605 0.01581268385052681 0.06056639924645424 -0.631630003452301 51.77058236537432 45.0 1.0 no 4150 chrVII_321975r 12894 essential YGL097W 196 - TCTTTTAACTTCCTTATTTT R|72|T R|72|K SRM1 Suppressor of Receptor Mutations 482.0 0 0 0 0 0.2636094065839022 P21827 0.932735025882721 0.955805003643036 0.0 0.0 0.2557662129402161 -0.3057459890842438 40.270808736212025 20.0 1.0 no 4151 chrVII_322037 12899 essential YGL097W 255 + ATCATTTCTTTTGCAGTCGG I|86|M silent|ATC>ATT|I|86 SRM1 Suppressor of Receptor Mutations 482.0 0 0 0 0 -0.11537377669487593 P21827 0.9598389863967896 0.01345430128276348 2.24478530883789 1.229200005531311 47.93646649472055 40.0 1.0 no 4152 chrVII_322176r 12905 essential YGL097W 397 - TTCGTCATCACTTGAGTCAT E|139|Q E|139|K D|138|H D|138|N SRM1 Suppressor of Receptor Mutations 482.0 0 1 0 0 -0.7925156056675114 P21827 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.15022727847099304 0.1302785724401474 0.02010164223611355 0.238169327378273 -0.8583999872207642 -0.7785999774932861 -1.100000023841858 -1.0362000465393066 47.609487092347315 40.0 1.0 no 4153 chrVII_322230r 12906 essential YGL097W 451 - TGACTCTCTTGGGATTTTAG E|156|D silent|GAG>GAA|E|156 E|156|Q E|156|K SRM1 Suppressor of Receptor Mutations 482.0 0 0 0 0 0.7790759220837447 P21827 0.94931298494339 0.956179976463318 0.9475290179252625 0.4173409938812256 0.1819690018892288 0.11944860219955444 44.86736476336886 40.0 1.0 no 4154 chrVII_322249 12907 essential YGL097W 467 + GTCATTTCCTCCCTTAGCGG S|157|* S|157|L SRM1 Suppressor of Receptor Mutations 482.0 0 0 0 0 0.7110291737616224 P21827 0.9298099875450134 -2.0317659378051762 58.859609134211894 55.00000000000001 1.0 no 4155 chrVII_322250 12908 essential YGL097W 468 + TCATTTCCTCCCTTAGCGGA S|157|* S|157|L P|159|A P|159|S SRM1 Suppressor of Receptor Mutations 482.0 0 0 0 0 -0.9645035001040068 P21827 0.9298099875450134 0.9562489986419678 0.9498909711837769 0.8597375154495239 0.4614904522895813 -2.0317659378051762 1.963763952255249 2.387053966522217 57.269980808856594 50.0 1.0 no 4156 chrVII_322259r 12909 essential YGL097W 480 - ACCTTGTGTCCCTCCGCTAA K|166|N silent|AAG>AAA|K|166 V|167|L V|167|I SRM1 Suppressor of Receptor Mutations 482.0 0 0 0 0 0.7995824863503389 P21827 0.9355990290641784 0.9539830088615416 0.9574310183525084 0.3259547054767609 0.3343369960784912 1.0 0.7761871814727783 2.6325597763061523 -0.1988767981529236 59.92892437011506 55.00000000000001 1.0 no 4157 chrVII_322760r 12922 essential YGL097W 981 - CTTCTGATAACAACGTTATC R|333|T R|333|K SRM1 Suppressor of Receptor Mutations 482.0 0 0 0 0 -2.5144875617744504 P21827 0.932735025882721 0.955805003643036 0.28741455078125 1.0 2.35192608833313 -0.6396759748458862 38.56271473100958 35.0 1.0 yes 4158 chrVII_322847 12926 essential YGL097W 1065 + AGACTAGACATGTTTGAAGT L|357|V silent|CTA>TTA|L|357 SRM1 Suppressor of Receptor Mutations 482.0 0 0 0 0 -0.3130348925282376 P21827 0.9512209892272948 0.691986620426178 2.2123701572418213 2.9611999988555913 40.37159214039656 35.0 1.0 no 4159 chrVII_329592 12931 high_effect YGL095C 996 - CCAGATAATTTTCTAAACTC G|339|R G|339|R VPS45 Vacuolar Protein Sorting 577.0 0 0 0 0 0.6719301882405554 P38932 0.941340982913971 0.941340982913971 0.002206607023254037 0.002206607023254037 37.10076093021468 30.0 0.0 no 4160 chrVII_329638 12933 high_effect YGL095C 950 - TATCCTCAATGGAATTTATT D|323|H D|323|N E|322|D silent|GAG>GAA|E|322 VPS45 Vacuolar Protein Sorting 577.0 0 0 0 0 0.4406711188333239 P38932 0.9486550092697144 0.956179976463318 0.94931298494339 0.0 0.0 0.5570988655090332 38.572679426244065 25.0 0.0 no 4161 chrVII_329641r 12934 high_effect YGL095C 944 + CAGCCAAATAAATTCCATTG S|316|R silent|AGC>AGT|S|316 Q|317|E Q|317|* VPS45 Vacuolar Protein Sorting 577.0 0 1 0 0 -0.3907365698294134 P38932 0.9417110085487366 0.9590039849281312 0.5244830250740051 0.4629298150539398 39.97167308694458 35.0 0.0 no 4162 chrVII_329720 12935 high_effect YGL095C 868 - TTCACCAAAATTCAAATACA E|296|Q E|296|K G|295|A G|295|D VPS45 Vacuolar Protein Sorting 577.0 0 0 0 0 -0.7699059072086676 P38932 0.956179976463318 0.9475290179252625 0.9499930143356324 0.9446240067481996 0.009124482050538065 0.007188548333942891 0.10071323812007904 0.0022257259115576744 34.78123461496915 25.0 0.0 no 4163 chrVII_329844r 12937 high_effect YGL095C 741 + TCAATGATCAATGAGTATAT S|248|* S|248|L VPS45 Vacuolar Protein Sorting 577.0 0 0 0 0 -3.3481617469331364 P38932 0.9298099875450134 0.0029226313345134263 34.73425174474852 25.0 0.0 yes 4164 chrVII_329859 12939 high_effect YGL095C 729 - ATCATTGATTGGTAGGTCCA M|249|I M|249|I VPS45 Vacuolar Protein Sorting 577.0 0 0 0 0 0.18852703304420687 P38932 0.9553959965705872 0.9553959965705872 0.0 0.0 48.958264536914946 40.0 0.0 no 4165 chrVII_329876r 12940 high_effect YGL095C 709 + TAACACCTTTACTTCAACCT T|238|R T|238|I P|239|A P|239|S VPS45 Vacuolar Protein Sorting 577.0 0 0 0 0 0.5048874654375889 P38932 0.9476869702339172 0.9472420215606691 0.9562489986419678 0.9498909711837769 0.001483946107327938 0.0016776879783719778 0.0 0.0 44.41103206301898 35.0 0.0 no 4166 chrVII_330030 12942 high_effect YGL095C 558 - GCTCCTTCATACCTGATATC G|192|A G|192|E A|193|P A|193|T VPS45 Vacuolar Protein Sorting 577.0 0 0 0 0 -0.3725518462822312 P38932 0.9499930143356324 0.9438679814338684 0.9573720097541808 0.9523990154266356 0.1679661124944687 0.14798405766487122 0.11923549324274064 1.0 51.30311232573428 45.0 0.0 no 4167 chrVII_330214r 12945 high_effect YGL095C 371 + CGACTTGGAAGCTGTTACTA D|125|E silent|GAC>GAT|D|125 VPS45 Vacuolar Protein Sorting 577.0 0 0 0 0 -0.4444011282207262 P38932 0.9532920122146606 1.0 45.7212396387231 45.0 0.0 no 4168 chrVII_330368 12949 high_effect YGL095C 220 - AACTAAGCACCTTAAATGCC V|80|L V|80|I VPS45 Vacuolar Protein Sorting 577.0 0 0 0 0 -0.3112093578656913 P38932 0.9539830088615416 0.9574310183525084 0.02230390533804893 0.02828357927501202 43.31208703281595 40.0 0.0 no 4169 chrVII_330449 12951 high_effect YGL095C 139 - CTCACTTTGAGTGGCACATA E|53|Q E|53|K S|52|T S|52|N VPS45 Vacuolar Protein Sorting 577.0 0 0 0 0 -0.9018406064493508 P38932 0.956179976463318 0.9475290179252625 0.9512869715690612 0.9536849856376648 0.4834163784980774 0.6514747142791748 0.06455089896917343 0.0045015071518719205 48.6412707382259 45.0 0.0 no 4170 chrVII_330464 12952 high_effect YGL095C 124 - ACATAAGGATATCGTAGGTG C|48|S C|48|Y VPS45 Vacuolar Protein Sorting 577.0 0 0 0 0 -0.2662334250410677 P38932 0.9421560168266296 0.9290120005607604 0.3051914870738983 0.01535086240619421 41.17776332327338 40.0 0.0 no 4171 chrVII_330499 12953 high_effect YGL095C 89 - ACAGCAAAACCTTAATCCTT silent|CTG>CTC|L|36 silent|CTG>CTA|L|36 L|35|F silent|TTG>TTA|L|35 VPS45 Vacuolar Protein Sorting 577.0 0 0 0 0 -0.14828372582805 P38932 0.9587849974632264 0.0 42.815853130095256 35.0 0.0 no 4172 chrVII_330515 12954 high_effect YGL095C 73 - CCTTTGGTGTTCATTGACAT R|31|T R|31|K VPS45 Vacuolar Protein Sorting 577.0 0 0 0 0 -0.13588249301975186 P38932 0.932735025882721 0.955805003643036 0.1191248670220375 1.0 48.74668740101367 40.0 0.0 no 4173 chrVII_334906r 12958 essential YGL093W 23 - CCTTCTCTCTACCCCCAATC K|14|N silent|AAG>AAA|K|14 E|13|D silent|GAG>GAA|E|13 SPC105 Spindle Pole Component 917.0 0 0 0 0 -0.5180050887604748 P53148 0.9355990290641784 0.94931298494339 59.162367394810765 55.00000000000001 1.0 no 4174 chrVII_334937r 12959 essential YGL093W 54 - TGCTTAAGAATGCCTTTCCC K|24|N silent|AAG>AAA|K|24 SPC105 Spindle Pole Component 917.0 0 0 0 0 -2.083417940002025 P53148 0.9355990290641784 0.0 50.841139730734426 45.0 1.0 yes 4175 chrVII_334938r 12960 essential YGL093W 55 - CTGCTTAAGAATGCCTTTCC K|24|N silent|AAG>AAA|K|24 SPC105 Spindle Pole Component 917.0 0 0 0 0 -2.8109687457858827 P53148 0.9355990290641784 0.0 48.97169818967495 45.0 1.0 yes 4176 chrVII_335371 12966 essential YGL093W 485 + ACAGCATGATCCCACATCAA Q|163|E Q|163|* H|164|D H|164|Y SPC105 Spindle Pole Component 917.0 0 0 0 0 -0.15614532009504936 P53148 0.9590039849281312 0.9473130106925964 0.9489949941635132 0.8069040179252625 0.22658956050872806 0.6726431846618652 49.50679852223095 45.0 1.0 no 4177 chrVII_335381r 12967 essential YGL093W 498 - TCAGTCATTTCCATTGATGT E|173|Q E|173|K M|171|I M|171|I SPC105 Spindle Pole Component 917.0 0 0 0 0 0.6558782995600283 P53148 0.956179976463318 0.9475290179252625 0.9553959965705872 0.9553959965705872 0.4083126783370972 0.17590367794036865 0.5326052308082581 0.5326052308082581 0.1904280036687851 0.38846999406814575 0.22757600247859955 0.22757600247859955 47.20865599419233 35.0 1.0 no 4178 chrVII_335382r 12968 essential YGL093W 499 - TTCAGTCATTTCCATTGATG E|173|Q E|173|K M|171|I M|171|I SPC105 Spindle Pole Component 917.0 0 0 0 0 0.518549672426744 P53148 0.956179976463318 0.9475290179252625 0.9553959965705872 0.9553959965705872 0.4083126783370972 0.17590367794036865 0.5326052308082581 0.5326052308082581 0.1904280036687851 0.38846999406814575 0.22757600247859955 0.22757600247859955 44.78508529717743 35.0 1.0 no 4179 chrVII_335435r 12971 essential YGL093W 552 - ATGCTTTCTCCCTCTACATC S|190|T S|190|N SPC105 Spindle Pole Component 917.0 0 0 0 0 1.190372451932648 P53148 0.9512869715690612 0.9536849856376648 0.7355160117149353 0.485606461763382 54.00988627699753 45.0 1.0 no 4180 chrVII_335646r 12977 essential YGL093W 763 - TCTTTCCACGCTATAGTCAG R|261|T R|261|K E|260|Q E|260|K SPC105 Spindle Pole Component 917.0 0 0 0 0 0.31935166736575377 P53148 0.932735025882721 0.955805003643036 0.956179976463318 0.9475290179252625 0.24245348572731015 1.0 0.0 0.0 49.88292262742408 45.0 1.0 no 4181 chrVII_335923 12981 essential YGL093W 1037 + TGTCTCTGATTATGCTGCAT silent|GTC>GTG|V|347 silent|GTC>GTT|V|347 S|348|C S|348|F SPC105 Spindle Pole Component 917.0 0 0 0 0 0.4563649668666279 P53148 0.945252001285553 0.9294660091400146 0.051249846816062934 0.0538431815803051 48.941093141974925 40.0 1.0 no 4182 chrVII_335886 12983 essential YGL093W 1000 + ATGCGTTTTCTTCTAATAAG A|335|G A|335|V SPC105 Spindle Pole Component 917.0 0 0 0 0 -1.0119187198478887 P53148 0.9484469890594482 0.9504740238189696 0.5307502150535583 0.3049952685832977 39.21284893873912 30.0 1.0 no 4183 chrVII_336026r 12986 essential YGL093W 1143 - TCAACATCGCTAAATGTAAT D|388|H D|388|N V|387|L V|387|I SPC105 Spindle Pole Component 917.0 0 1 0 0 -0.014077587191070525 P53148 0.9486550092697144 0.956179976463318 0.9539830088615416 0.9574310183525084 0.10362041741609572 1.0 1.0 0.5395367741584778 36.987635303142035 30.0 1.0 no 4184 chrVII_336027r 12987 essential YGL093W 1144 - ATCAACATCGCTAAATGTAA D|388|H D|388|N V|387|L V|387|I SPC105 Spindle Pole Component 917.0 0 1 0 0 -4.0466915082220805 P53148 0.9486550092697144 0.956179976463318 0.9539830088615416 0.9574310183525084 0.10362041741609572 1.0 1.0 0.5395367741584778 36.987635303142035 30.0 1.0 yes 4185 chrVII_336039 12989 essential YGL093W 1153 + GCGATGTTGATAATAAGATT S|385|R silent|AGC>AGT|S|385 SPC105 Spindle Pole Component 917.0 1 Series([], Name: modification, dtype: object) 0 0 0 -1.4673475460736247 P53148 0.9417110085487366 0.525424063205719 37.076480978224204 30.0 1.0 no 4186 chrVII_336120r 12994 essential YGL093W 1237 - ATCTTCTTCATCGTCTGTCG D|419|H D|419|N E|418|Q E|418|K SPC105 Spindle Pole Component 917.0 0 1 0 0 -0.0737428034336256 P53148 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 50.26535566752607 45.0 1.0 no 4187 chrVII_336195r 12995 essential YGL093W 1312 - CTGCCCTTCCTTGTCTATTT silent|GGG>GGC|G|443 silent|GGG>GGA|G|443 G|443|A G|443|E SPC105 Spindle Pole Component 917.0 0 0 0 0 0.3254578050535236 P53148 0.9499930143356324 0.9438679814338684 57.008824549715825 45.0 1.0 no 4188 chrVII_336334 13000 essential YGL093W 1448 + GCTTAACAGCTTTAATTTTG L|484|V L|484|F N|485|K silent|AAC>AAT|N|485 SPC105 Spindle Pole Component 917.0 0 0 0 0 0.7855455362532182 P53148 0.9512209892272948 0.9587849974632264 0.9439849853515624 0.39703017473220825 0.13987404108047485 1.0 39.43251970079235 30.0 1.0 no 4189 chrVII_336537r 13005 essential YGL093W 1654 - TTGCTTCATTTTCTCATCCG K|557|N silent|AAG>AAA|K|557 M|556|I M|556|I SPC105 Spindle Pole Component 917.0 0 0 0 0 -0.1183998702625007 P53148 0.9355990290641784 0.9553959965705872 0.9553959965705872 0.026131067425012592 0.6765314340591431 0.6765314340591431 49.54414842697293 40.0 1.0 no 4190 chrVII_338351r 13020 essential YGL092W 448 - GAACAGACCACCATTTTGCG silent|CTG>CTC|L|155 silent|CTG>CTA|L|155 NUP145 NUclear Pore 1317.0 0 0 0 0 0.4624696850317659 P49687 48.44270445742575 50.0 1.0 no 4191 chrVII_338377 13022 essential YGL092W 471 + AAGCCTACTACAACCCCTGC P|159|A P|159|S P|159|R P|159|L NUP145 NUclear Pore 1317.0 0 0 0 0 0.3799033383413622 P49687 0.8538060188293457 1.0 0.5129252076148987 0.2979559898376465 55.04305258522726 55.00000000000001 1.0 no 4192 chrVII_338590r 13040 essential YGL092W 687 - TTACTTATGTTAATTCCATA S|235|T S|235|N NUP145 NUclear Pore 1317.0 0 0 0 0 0.822011895309215 P49687 1.0 0.5962913036346436 37.42330450389773 20.0 1.0 no 4193 chrVII_338601 13041 essential YGL092W 695 + TAACATAAGTAATGTTCCTA N|233|K silent|AAC>AAT|N|233 NUP145 NUclear Pore 1317.0 0 0 0 0 0.5324902460673492 P49687 0.0 36.4257765852451 25.0 1.0 no 4194 chrVII_338653 13043 essential YGL092W 747 + TCTTCTCTATCAGATGTGAA S|250|C S|250|F S|251|C S|251|F NUP145 NUclear Pore 1317.0 0 1 0 0 0.6404529935440634 P49687 0.051692921668291085 0.03568834438920021 0.02865119837224484 0.020562082529067997 42.99227543365129 35.0 1.0 no 4195 chrVII_338692r 13044 essential YGL092W 789 - CTTCTATTTTCAATTGGTTT R|269|T R|269|K NUP145 NUclear Pore 1317.0 0 1 0 0 0.3671707340060412 P49687 0.023253794759511948 1.0 40.62091991154182 25.0 1.0 no 4196 chrVII_338693r 13045 essential YGL092W 790 - TCTTCTATTTTCAATTGGTT R|270|T R|270|K R|269|T R|269|K NUP145 NUclear Pore 1317.0 0 1 0 0 0.26040266707809023 P49687 0.029051238670945168 0.31890568137168884 0.023253794759511948 1.0 41.3241934197344 25.0 1.0 no 4197 chrVII_338765r 13048 essential YGL092W 862 - ACTCACTAAACTTGACTGTG silent|GTG>GTC|V|293 silent|GTG>GTA|V|293 S|294|T S|294|N NUP145 NUclear Pore 1317.0 0 0 0 0 0.5332038229599081 P49687 0.19213217496871948 0.9976016879081726 41.01074214483492 40.0 1.0 no 4198 chrVII_338863r 13051 essential YGL092W 960 - GAACCTGCTCCATTCAGCCA G|326|A G|326|D G|326|R G|326|S NUP145 NUclear Pore 1317.0 0 0 0 0 -0.31360800892354146 P49687 0.8260458707809448 0.5009360313415527 0.3941673040390015 1.0 0.6846666932106018 0.6922667026519775 0.7592666745185852 0.8003332614898682 57.69281694553665 55.00000000000001 1.0 no 4199 chrVII_338910 13052 essential YGL092W 1004 + TTCTTCAAAGATGACTTCTT S|336|C S|336|F S|337|* S|337|L NUP145 NUclear Pore 1317.0 0 0 0 0 0.058532081447697226 P49687 0.06612308323383331 0.07953911274671555 0.3581865131855011 39.761307114647934 30.0 1.0 no 4200 chrVII_339303r 13063 essential YGL092W 1400 - ACAAACGCTCCAGCTGTTCT L|473|F silent|TTG>TTA|L|473 R|472|P R|472|H NUP145 NUclear Pore 1317.0 0 0 0 0 -2.264901278769792 P49687 0.024362772703170776 0.2770634293556213 0.1949513852596283 -0.37398600578308105 1.8520259857177732 0.6769019961357117 -0.062206000089645386 52.10926061233772 50.0 1.0 yes 4201 chrVII_339506r 13069 essential YGL092W 1603 - CCCATGCCCAATCATTGGTT G|541|R G|541|R G|541|A G|541|E NUP145 NUclear Pore 1317.0 0 0 0 0 0.4076952719615576 P49687 0.0 0.0 0.0 0.0 4.380348205566406 4.380348205566406 4.744939804077148 4.215792179107666 56.258939019980346 50.0 1.0 no 4202 chrVII_339708 13075 essential YGL092W 1802 + AGTCAATCATTTTAGCATTT silent|GTC>GTG|V|602 silent|GTC>GTT|V|602 NUP145 NUclear Pore 1317.0 0 0 0 0 1.1723846038662775 P49687 40.4343758731066 25.0 1.0 no 4203 chrVII_339710 13076 essential YGL092W 1804 + TCAATCATTTTAGCATTTGG silent|GTC>GTG|V|602 silent|GTC>GTT|V|602 H|604|D H|604|Y NUP145 NUclear Pore 1317.0 0 0 0 0 -0.15385116736913754 P49687 0.0 0.0 0.9233620166778564 -0.7393100261688232 1.0938199758529663 -0.25267601013183594 40.38436693641364 30.0 1.0 no 4204 chrVII_339859 13078 essential YGL092W 1953 + CTCAAAACAGATGGCACTTT silent|CTC>CTG|L|652 silent|CTC>CTT|L|652 NUP145 NUclear Pore 1317.0 0 0 0 0 -0.5036569019672892 P49687 42.076817855820366 40.0 1.0 no 4205 chrVII_339972 13080 essential YGL092W 2066 + CCCTAAACTTGACGTTTCTA P|690|R P|690|L P|690|A P|690|S NUP145 NUclear Pore 1317.0 0 1 0 0 -0.06217119939217175 P49687 0.0 0.0 0.0 0.0 45.75429460178998 40.0 1.0 no 4206 chrVII_339972r 13081 essential YGL092W 2069 - CCTTAGAAACGTCAAGTTTA K|696|N silent|AAG>AAA|K|696 NUP145 NUclear Pore 1317.0 0 1 0 0 -0.03264833015191198 P49687 1.0 40.56176397063643 35.0 1.0 no 4207 chrVII_339978 13084 essential YGL092W 2072 + ACTTGACGTTTCTAAGGATT L|692|V L|692|F D|693|E silent|GAC>GAT|D|693 NUP145 NUclear Pore 1317.0 0 1 0 0 -0.4532725432003758 P49687 0.03382730484008789 0.15994597971439362 0.29614314436912537 42.33730939524628 35.0 1.0 no 4208 chrVII_340122 13086 essential YGL092W 2216 + TAACGCAAAACTCATCATGA N|740|K silent|AAC>AAT|N|740 A|741|G A|741|V NUP145 NUclear Pore 1317.0 0 0 0 0 -0.0010776593538710038 P49687 0.9494764804840088 0.338591992855072 0.26273223757743835 38.06388052194831 35.0 1.0 no 4209 chrVII_340338r 13087 essential YGL092W 2435 - TTTCACTAATTTGTGGGTAT E|818|Q E|818|K S|817|T S|817|N NUP145 NUclear Pore 1317.0 0 0 0 0 -0.6938070106281116 P49687 0.6035829186439514 0.86272132396698 0.6647957563400269 0.4991439282894135 41.92668514045084 30.0 1.0 no 4210 chrVII_340403 13089 essential YGL092W 2497 + CCTCTAGTGATTACAATCTA S|834|C S|834|F silent|ACC>ACG|T|833 silent|ACC>ACT|T|833 NUP145 NUclear Pore 1317.0 0 0 0 0 -0.451130580556036 P49687 0.0661010891199112 0.091381274163723 43.081189539911115 35.0 1.0 no 4211 chrVII_340677 13098 essential YGL092W 2771 + GAGCGTTTTGATATCCTATT S|925|R silent|AGC>AGT|S|925 NUP145 NUclear Pore 1317.0 0 0 0 0 0.4000516139659277 P49687 0.00926118716597557 45.687625883388755 35.0 1.0 no 4212 chrVII_340710r 13101 essential YGL092W 2807 - CCGCTAAATCACGTATCCTT A|942|P A|942|T silent|GCG>GCC|A|942 silent|GCG>GCA|A|942 NUP145 NUclear Pore 1317.0 0 0 0 0 -2.301177636836978 P49687 0.04209794849157333 0.03395859152078628 48.600398298826754 45.0 1.0 yes 4213 chrVII_342366 13105 essential YGL091C 657 - TCTAATAAAGCTACTTCCTG D|226|H D|226|N NBP35 Nucleotide Binding Protein 328.0 0 0 0 0 -0.7434484325976093 P52920 0.9486550092697144 0.956179976463318 0.0 0.0 40.6139308482791 35.0 0.0 no 4214 chrVII_342701 13118 essential YGL091C 322 - TCCACATATATCTAAATCCA G|114|R G|114|R G|114|A G|114|E NBP35 Nucleotide Binding Protein 328.0 0 0 0 0 -5.007079533336536 P52920 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.0 0.0 0.0 0.0 41.502420703802564 30.0 0.0 yes 4215 chrVII_342933 13124 essential YGL091C 90 - TTACCTGCCATGTCTGATTC G|36|A G|36|D G|36|R G|36|S NBP35 Nucleotide Binding Protein 328.0 0 0 0 0 0.4424771299473165 P52920 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.0 0.0 0.0 0.0 51.81657943536169 45.0 0.0 no 4216 chrVII_342957r 13130 essential YGL091C 63 + CCGGAACCAGAACACTGTCC P|22|R P|22|L P|24|A P|24|S NBP35 Nucleotide Binding Protein 328.0 0 0 0 0 0.11997024476661895 P52920 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.15596933662891388 0.08880695700645448 0.2014414221048355 0.2710615396499634 52.29634771142986 60.0 0.0 no 4217 chrVII_367302r 13136 essential YGL075C 764 + AGACACCATATCTTTCCTAA D|256|E silent|GAC>GAT|D|256 T|257|S T|257|I MPS2 MonoPolar Spindle 387.0 0 0 0 0 -0.008622048100138002 P53159 0.9954699873924256 0.9910879731178284 0.9891359806060792 1.0 0.14664267003536224 0.8420984745025635 45.18756202208249 35.0 0.0 no 4218 chrVII_367386r 13142 essential YGL075C 680 + ATCTGACCCAGGATCACCTC S|228|C S|228|F D|229|E silent|GAC>GAT|D|229 MPS2 MonoPolar Spindle 387.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.5361973623917448 P53159 0.9182299971580504 0.9007340073585509 0.9257869720458984 55.77356963659304 55.00000000000001 0.0 no 4219 chrVII_367542r 13146 essential YGL075C 524 + TGCGAAACAAAGCCTCCTTC A|176|G A|176|V MPS2 MonoPolar Spindle 387.0 0 0 0 0 -0.1261605172353994 P53159 0.9230139851570128 0.9222400188446044 0.613930881023407 0.5259556174278259 47.87861015950165 50.0 0.0 no 4220 chrVII_367682r 13151 essential YGL075C 384 + AACAAGAACAAGAATACAGA N|129|K silent|AAC>AAT|N|129 MPS2 MonoPolar Spindle 387.0 0 0 0 0 0.3326112168660673 P53159 0.9845200181007384 0.6935471296310425 31.654679770422767 30.0 0.0 no 4221 chrVII_367703 13153 essential YGL075C 366 - TTCTCAACCAGAAATTTGGA E|128|D silent|GAG>GAA|E|128 E|128|Q E|128|K MPS2 MonoPolar Spindle 387.0 0 0 0 0 0.2343794782370971 P53159 0.9933249950408936 1.0004899501800537 0.9891330003738404 0.2860304117202759 0.07047135382890701 0.17550985515117645 41.19167563994762 35.0 0.0 no 4222 chrVII_367775r 13154 essential YGL075C 291 + ATCTTAGAAAACGCGTTCAT I|98|M silent|ATC>ATT|I|98 MPS2 MonoPolar Spindle 387.0 0 0 0 0 -1.9067053673714616 P53159 0.9338020086288452 0.12795427441596985 40.42356665212367 35.0 0.0 no 4223 chrVII_367973 13156 essential YGL075C 96 - TCAATTATCTCGATTAGCTT E|39|Q E|39|K MPS2 MonoPolar Spindle 387.0 0 0 0 0 -0.3967460623824832 P53159 1.0004899501800537 0.9891330003738404 0.07152482122182846 0.07929593324661255 41.393624122333215 30.0 0.0 no 4224 chrVII_368047r 13160 essential YGL075C 19 + ATGCTATTTTTGAGTACGCA A|8|G A|8|V MPS2 MonoPolar Spindle 387.0 0 0 0 0 -0.09960642386376696 P53159 0.9919250011444092 0.991150975227356 45.05589479970222 35.0 0.0 no 4225 chrVII_368950 13167 essential YGL073W 197 + TCCGCAGTCAGCAGCATCGC P|67|R P|67|L P|67|A P|67|S HSF1 Heat Shock transcription Factor 833.0 0 0 0 0 -1.5330624095629926 P10961 0.12772135436534882 1.0 0.5880917310714722 0.2602623999118805 61.17053853653027 65.0 1.0 no 4226 chrVII_369012 13171 essential YGL073W 259 + CCACCAGTACACATTTAGTA T|88|S T|88|I silent|TCC>TCG|S|87 silent|TCC>TCT|S|87 HSF1 Heat Shock transcription Factor 833.0 0 0 0 0 -0.2189122580676528 P10961 0.8393888473510742 0.268784373998642 47.56061133251563 40.0 1.0 no 4227 chrVII_369134 13175 essential YGL073W 381 + GCGCATCCACCAGTTCCTTA H|129|D H|129|Y A|128|G A|128|V HSF1 Heat Shock transcription Factor 833.0 0 0 0 0 1.1950596661466353 P10961 0.7126041054725647 0.8166919350624084 0.3731977641582489 0.2793550491333008 59.7300591065835 55.00000000000001 1.0 no 4228 chrVII_369270 13183 essential YGL073W 517 + CTGCATTTGTTAATAAACTA A|174|G A|174|V HSF1 Heat Shock transcription Factor 833.0 0 0 0 0 -0.24402046949469225 P10961 0.034482132643461234 0.028159944340586662 35.739939044802156 25.0 1.0 no 4229 chrVII_369348 13184 essential YGL073W 595 + AATCTTTTATTGTCACGAAT S|200|C S|200|F HSF1 Heat Shock transcription Factor 833.0 0 0 0 0 1.4275949434653916 P10961 0.0 0.0 37.39560329749014 25.0 1.0 no 4230 chrVII_369435 13186 essential YGL073W 682 + GACAATTGAACATGTATGGA Q|229|E Q|229|* HSF1 Heat Shock transcription Factor 833.0 0 0 0 0 -1.0847160686696793 P10961 0.0 38.23350579967109 35.0 1.0 no 4231 chrVII_369786r 13190 essential YGL073W 1036 - CTCTAATTCCCCCAAAATCG E|352|Q E|352|K HSF1 Heat Shock transcription Factor 833.0 0 0 0 0 0.9260557240449372 P10961 0.021418258547782898 0.020514203235507008 46.96270328311675 45.0 1.0 no 4232 chrVII_369823r 13191 essential YGL073W 1073 - AATCTTTGGAAATTGCAATC D|364|H D|364|N HSF1 Heat Shock transcription Factor 833.0 0 1 0 0 0.19288919522800985 P10961 0.0 0.0 36.71170173368017 30.0 1.0 no 4233 chrVII_369978r 13196 essential YGL073W 1228 - CAGCCCGTCCATAATCATTT silent|GGG>GGC|G|415 silent|GGG>GGA|G|415 G|415|A G|415|E HSF1 Heat Shock transcription Factor 833.0 0 0 0 0 0.3834261749333384 P10961 0.8746547102928162 1.0 52.09709783030058 45.0 1.0 no 4234 chrVII_370007r 13197 essential YGL073W 1257 - AGCTTTTCATTATTAACTTT K|425|N silent|AAG>AAA|K|425 HSF1 Heat Shock transcription Factor 833.0 0 0 0 0 0.08522210568288546 P10961 0.4906168580055237 38.305803747316645 20.0 1.0 no 4235 chrVII_370166r 13200 essential YGL073W 1416 - ATACTATTGTCATCATTGTT S|478|T S|478|N HSF1 Heat Shock transcription Factor 833.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.6977655076401774 P10961 0.6163489818572998 0.5283769369125366 40.50627389550323 25.0 1.0 no 4236 chrVII_370310 13202 essential YGL073W 1557 + TACAATTCCAACAATAATGC Y|520|* silent|TAC>TAT|Y|520 HSF1 Heat Shock transcription Factor 833.0 0 0 0 0 -0.4673115019150788 P10961 36.46418594439717 30.0 1.0 no 4237 chrVII_372100r 13206 high_effect YGL071W 91 - TACATATTCACTAGCACTTT V|37|L V|37|I 0 0 0 0 0.646928130259351 P22149 0.9539830088615416 0.9574310183525084 41.8653235532721 30.0 1.0 no 4238 chrVII_372215r 13209 high_effect YGL071W 206 - GAACATGCTGATCAATATTG V|75|L V|75|I 0 0 0 0 -0.02613536764359714 P22149 0.9539830088615416 0.9574310183525084 38.08808627452237 35.0 1.0 no 4239 chrVII_372214r 13210 high_effect YGL071W 205 - AACATGCTGATCAATATTGA V|75|L V|75|I Q|73|H silent|CAG>CAA|Q|73 0 0 0 0 -0.4687354425908857 P22149 0.9539830088615416 0.9574310183525084 0.9570760130882264 38.08808627452237 30.0 1.0 no 4240 chrVII_372236 13211 high_effect YGL071W 224 + TCATACCTCAACATCGCCGA H|76|D H|76|Y T|77|S T|77|I 0 0 0 0 0.2783855067256404 P22149 0.9473130106925964 0.9489949941635132 0.9491789937019348 0.9472420215606691 51.1135770176939 50.0 1.0 no 4241 chrVII_372327r 13214 high_effect YGL071W 318 - TCGGACTTATCTTCAAAGTT D|113|H D|113|N K|111|N silent|AAG>AAA|K|111 0 0 0 0 -0.1238400728327701 P22149 0.9486550092697144 0.956179976463318 0.9355990290641784 0.004838510882109404 0.025014540180563927 0.004438135307282209 42.18188399148204 35.0 1.0 no 4242 chrVII_372346r 13216 high_effect YGL071W 337 - TTGCAACCAAGGCTTAATAT L|118|F silent|TTG>TTA|L|118 W|117|C W|117|* 0 0 0 0 1.2489420136825558 P22149 0.9587849974632264 0.8858469724655151 0.0053524645045399675 0.0 42.694692083389896 35.0 1.0 no 4243 chrVII_372381r 13217 high_effect YGL071W 372 - ATCACAAGTTCTATTCCTTG silent|GTG>GTC|V|130 silent|GTG>GTA|V|130 V|130|L V|130|M 0 0 0 0 -0.34413916604266603 P22149 0.9539830088615416 0.9587630033493042 0.006636390928179026 0.0019859997555613518 43.989836898213575 35.0 1.0 no 4244 chrVII_372489r 13219 high_effect YGL071W 480 - TCTTCGTGGTCCTGTCCTTT D|167|H D|167|N E|166|Q E|166|K 0 0 0 0 0.5248899221222565 P22149 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 59.26662898737129 50.0 1.0 no 4245 chrVII_372558 13221 high_effect YGL071W 546 + TCTAATGCCACAGTAACCAA S|183|C S|183|F 0 1 0 0 0.18539415782592955 P22149 0.945252001285553 0.9294660091400146 0.08402081578969955 0.2365572601556778 45.070802047799084 40.0 1.0 no 4246 chrVII_372503r 13222 high_effect YGL071W 494 - TCTTGGATTTCTCGTCTTCG K|171|N silent|AAG>AAA|K|171 0 0 0 0 0.7391020717220689 P22149 0.9355990290641784 49.41438014456031 45.0 1.0 no 4247 chrVII_373020 13229 high_effect YGL071W 1008 + TTACCCTCTGTAAATAACAC P|338|A P|338|S P|338|R P|338|L 0 0 0 0 -0.1568789993669784 P22149 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.3624666929244995 0.3644149601459503 0.21159572899341586 0.20972862839698792 40.97471680527673 35.0 1.0 no 4248 chrVII_373054r 13232 high_effect YGL071W 1045 - TTTCGGTTTCCTTACGTTAT silent|CCG>CCC|P|354 silent|CCG>CCA|P|354 0 0 0 0 0.11643974100658325 P22149 47.664827857149646 35.0 1.0 no 4249 chrVII_373182 13234 high_effect YGL071W 1170 + CACTCATCTACAGCATTTTC H|391|Q silent|CAC>CAT|H|391 S|392|* S|392|L 0 0 0 0 0.2931421224873408 P22149 0.9588389992713928 0.9298099875450134 0.3555257320404053 0.09087597578763963 45.97805096534313 40.0 1.0 no 4250 chrVII_373318 13236 high_effect YGL071W 1306 + AATCGCCGCATCCACATAGC S|437|W S|437|L P|438|A P|438|S 0 0 0 0 -0.09084252939228832 P22149 0.9288619756698608 0.9298099875450134 0.9562489986419678 0.9498909711837769 0.01449877955019474 0.11230108141899107 0.4308573007583618 0.4746338129043579 53.81536521294356 55.00000000000001 1.0 no 4251 chrVII_375208 13247 essential YGL068W 121 + CATCACATAAGGATGATGTA S|42|* S|42|L H|43|D H|43|Y MNP1 Mitochondrial-Nucleoid Protein 194.0 0 0 0 0 -2.284203031504454 P53163 0.9073870182037354 0.9458060264587402 0.9464880228042604 0.28621044754981995 0.6411715745925903 0.9510827660560608 39.383713344528864 35.0 1.0 yes 4252 chrVII_375332 13248 essential YGL068W 245 + TCCAGAAATTTCCATGCCTA P|83|R P|83|L P|83|A P|83|S MNP1 Mitochondrial-Nucleoid Protein 194.0 0 0 0 0 0.6672827262086379 P53163 0.9249039888381958 0.9246829748153688 0.9426339864730836 0.932117998600006 0.15616300702095032 0.12006140500307085 0.625710129737854 0.9657506942749025 48.76756193723338 40.0 1.0 no 4253 chrVII_375295r 13249 essential YGL068W 211 - TTTCAGCTCGTTGATTAAAC silent|CTG>CTC|L|76 silent|CTG>CTA|L|76 E|75|D silent|GAG>GAA|E|75 MNP1 Mitochondrial-Nucleoid Protein 194.0 0 0 0 0 -0.4859082193424401 P53163 0.92986798286438 0.606305718421936 40.927274156838735 35.0 1.0 no 4254 chrVII_375333 13250 essential YGL068W 246 + CCAGAAATTTCCATGCCTAT P|83|R P|83|L MNP1 Mitochondrial-Nucleoid Protein 194.0 0 0 0 0 -0.2093547980378564 P53163 0.9249039888381958 0.9246829748153688 0.15616300702095032 0.12006140500307085 47.767310063349846 40.0 1.0 no 4255 chrVII_375348r 13252 essential YGL068W 264 - CCTGCCATGAATCCGCCCAT G|95|R G|95|S A|94|P A|94|T MNP1 Mitochondrial-Nucleoid Protein 194.0 0 0 0 0 0.15121858051184536 P53163 0.9224320054054259 0.9315779805183412 0.9421370029449464 0.9307979941368104 59.95028611152628 60.0 1.0 no 4256 chrVII_375482 13254 essential YGL068W 395 + CTCGTTCGACACGAAGACTA S|133|W S|133|L F|134|L silent|TTC>TTT|F|134 MNP1 Mitochondrial-Nucleoid Protein 194.0 0 1 0 0 -0.3908767964919647 P53163 0.9130470156669616 0.9139950275421144 0.924991011619568 0.0007616031798534094 0.0048237359151244155 0.02293882705271244 45.4987457655684 50.0 1.0 no 4257 chrVII_380166r 13256 essential YGL065C 1083 + ACTATCAAATCTTACGTTGC T|362|S T|362|I I|363|M silent|ATC>ATT|I|363 ALG2 Asparagine-Linked Glycosylation 503.0 0 0 0 0 -0.5694095364869212 P43636 0.9491789937019348 0.9472420215606691 0.9598389863967896 0.1496298909187317 0.003771729301661253 0.007940237410366535 40.88564339560503 35.0 0.0 no 4258 chrVII_380202 13258 essential YGL065C 1050 - CCATTGTTTACTGCTAGTAC G|357|R G|357|R ALG2 Asparagine-Linked Glycosylation 503.0 0 0 0 0 -0.8166546535338938 P43636 0.941340982913971 0.941340982913971 0.0 0.0 46.89647226188612 40.0 0.0 no 4259 chrVII_380259r 13262 essential YGL065C 990 + ACACCAGCATATGAGCACTT P|332|A P|332|S T|331|R T|331|I ALG2 Asparagine-Linked Glycosylation 503.0 0 0 0 0 -2.612515173800002 P43636 0.9562489986419678 0.9498909711837769 0.9476869702339172 0.9472420215606691 0.0 0.0 0.0 0.0 49.79433273307063 45.0 0.0 yes 4260 chrVII_380505r 13264 essential YGL065C 744 + AACGTTAAGTTAGTTATTTG N|249|K silent|AAC>AAT|N|249 ALG2 Asparagine-Linked Glycosylation 503.0 0 0 0 0 -0.2649751408409968 P43636 0.9439849853515624 0.6026986241340637 35.175578286072835 25.0 0.0 no 4261 chrVII_380590 13265 essential YGL065C 662 - TCTCAAAACGATTTATACTT E|227|Q E|227|K E|227|D silent|GAG>GAA|E|227 ALG2 Asparagine-Linked Glycosylation 503.0 0 0 0 0 -1.03361000268152 P43636 0.956179976463318 0.9475290179252625 0.94931298494339 0.0 0.0 0.0 35.25857765105968 25.0 0.0 no 4262 chrVII_380689r 13266 essential YGL065C 560 + AGACGTCATTTATCCATGCG D|188|E silent|GAC>GAT|D|188 silent|GTC>GTG|V|189 silent|GTC>GTT|V|189 ALG2 Asparagine-Linked Glycosylation 503.0 0 0 0 0 -0.17617937693817035 P43636 0.9532920122146606 1.0 47.837156861450694 45.0 0.0 no 4263 chrVII_380802 13267 essential YGL065C 450 - AACTGTTCTATTAAGTCAAA Q|156|H silent|CAG>CAA|Q|156 ALG2 Asparagine-Linked Glycosylation 503.0 0 0 0 0 0.05096857967417382 P43636 0.9570760130882264 0.037407319992780685 35.13685962371449 25.0 0.0 no 4264 chrVII_380863r 13271 essential YGL065C 386 + TCATTTCCCCGACCAATTAT H|130|D H|130|Y F|131|L silent|TTC>TTT|F|131 ALG2 Asparagine-Linked Glycosylation 503.0 0 0 0 0 -1.444127207445246 P43636 0.9473130106925964 0.9489949941635132 0.9387490153312684 0.022189248353242874 0.005317221861332655 0.013393980450928213 50.19846899786261 40.0 0.0 no 4265 chrVII_381165r 13273 essential YGL065C 84 + GCATTAGGTCTACAGCAACA A|29|G A|29|V ALG2 Asparagine-Linked Glycosylation 503.0 0 0 0 0 0.22094351105869967 P43636 0.9484469890594482 0.9504740238189696 0.0 0.0 48.26827434512495 45.0 0.0 no 4266 chrVII_381205 13275 essential YGL065C 47 - TTTCAGCGCCCCCAATACCT E|22|Q E|22|K A|21|P A|21|T ALG2 Asparagine-Linked Glycosylation 503.0 0 0 0 0 -1.8201144206605653 P43636 0.956179976463318 0.9475290179252625 0.9573720097541808 0.9523990154266356 0.0 0.0 0.0 0.0 59.70793465486429 55.00000000000001 0.0 no 4267 chrVII_381215r 13276 essential YGL065C 34 + TTCATCCAGACCTAGGTATT H|13|D H|13|Y P|14|A P|14|S ALG2 Asparagine-Linked Glycosylation 503.0 0 0 0 0 -4.738444383833887 P43636 0.9473130106925964 0.9489949941635132 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 49.62526819738224 40.0 0.0 yes 4268 chrVII_381222r 13278 essential YGL065C 27 + GCTTTTATTCATCCAGACCT A|10|G A|10|V ALG2 Asparagine-Linked Glycosylation 503.0 0 0 0 0 0.20424009287677525 P43636 0.9484469890594482 0.9504740238189696 0.0023726916406303644 1.0 51.165815527181614 40.0 0.0 no 4269 chrVII_389359r 13282 essential YGL061C 330 + ATCAACATTCATTCTCAAGC I|111|M silent|ATC>ATT|I|111 N|112|K silent|AAC>AAT|N|112 DUO1 Death Upon Overproduction 247.0 0 0 0 0 -0.041205074966767286 P53168 0.009038220159709455 0.2742397487163544 41.802947644652185 35.0 0.0 no 4270 chrVII_389587 13283 essential YGL061C 105 - GCTCCACCTCCTGTGCTTTT G|41|A G|41|E A|42|P A|42|T DUO1 Death Upon Overproduction 247.0 0 0 0 0 0.5963851031717384 P53168 62.95735941672154 55.00000000000001 0.0 no 4271 chrVII_393995r 13287 high_effect YGL058W 12 - CTCATCAACCTTCTTCTAGC M|10|I M|10|I L|9|F silent|TTG>TTA|L|9 0 0 0 0 0.7818090735846468 P06104 0.9258790016174316 0.9258790016174316 0.8540800213813782 0.35887205600738525 0.35887205600738525 0.006959869060665369 0.7300999760627747 0.7300999760627747 16.391372680664062 0.4248400032520294 0.4248400032520294 49.76785915851008 45.0 1.0 no 4272 chrVII_394066 13288 high_effect YGL058W 80 + ACCATTACCTGATAACGTCA P|28|R P|28|L P|28|A P|28|S 0 0 0 0 -0.8030759936697304 P06104 0.7546219825744629 0.7393109798431396 0.7900630235671997 0.7948700189590454 0.0020599765703082085 0.004077189601957798 0.012800781987607479 0.006115548778325318 2.3237600326538086 1.8170599937438965 2.7695000171661377 2.8750600814819336 46.156466966076486 40.0 1.0 no 4273 chrVII_394217 13295 high_effect YGL058W 231 + CATCCCAATGTCTATGCAAA P|79|A P|79|S P|79|R P|79|L 0 0 0 0 0.5844151584021426 P06104 0.7891700267791748 0.8134160041809082 0.7523980140686035 0.7244459986686707 0.0 0.0 0.0 0.0 3.4329800605773926 5.663879871368407 14.416740417480467 4.848899841308594 45.59498826391882 40.0 1.0 no 4274 chrVII_398763r 13305 essential YGL055W 138 - CCAAAACCGTTGACAATTCT G|53|R G|53|S G|51|A G|51|D OLE1 OLEic acid requiring 510.0 0 0 0 0 -0.8627443674389303 P21147 0.9727219939231871 0.991388976573944 0.9903749823570251 0.9780880212783812 42.871465807981046 40.0 1.0 no 4275 chrVII_398774 13306 essential YGL055W 146 + CAACGGTTTTGGTTCTTTAA N|50|K silent|AAC>AAT|N|50 OLE1 OLEic acid requiring 510.0 0 0 0 0 0.31843636643363193 P21147 0.9845200181007384 42.85947912796826 35.0 1.0 no 4276 chrVII_399100r 13316 essential YGL055W 475 - AGACCATAATCTATGGTAAC W|164|C W|164|* W|164|S W|164|* OLE1 OLEic acid requiring 510.0 0 0 0 0 -1.3988243090370829 P21147 0.9208570122718812 0.9205849766731262 0.001127073890529573 0.0014782021753489973 39.65981201617143 35.0 1.0 no 4277 chrVII_399171 13320 essential YGL055W 543 + TTCGGTTGTGCTTCCGTTGA F|182|L silent|TTC>TTT|F|182 OLE1 OLEic acid requiring 510.0 0 0 0 0 0.8979114581339886 P21147 0.9584370255470276 0.8471574783325195 55.282222765438966 50.0 1.0 no 4278 chrVII_399184r 13321 essential YGL055W 559 - CCATTTAGCGGACCCTTCAA W|193|S W|193|* OLE1 OLEic acid requiring 510.0 0 0 0 0 -4.444508986038408 P21147 0.929980993270874 0.016944879665970802 53.16684610192715 50.0 1.0 yes 4279 chrVII_399247r 13323 essential YGL055W 622 - AGCGTCATAAGGATCTCTCA A|214|P A|214|T D|213|H D|213|N OLE1 OLEic acid requiring 510.0 0 0 0 0 -0.817406690349425 P21147 0.9770879745483398 0.9687960147857666 0.965224027633667 0.97645902633667 0.03725218027830124 0.1614886224269867 0.02767280302941799 0.2835954427719116 48.641270738225785 45.0 1.0 no 4280 chrVII_399258r 13325 essential YGL055W 633 - AGACCTCTACGAGCGTCATA G|217|A G|217|D G|217|R G|217|S OLE1 OLEic acid requiring 510.0 0 0 0 0 -2.4684365559489665 P21147 0.9903749823570251 0.9780880212783812 0.9727219939231871 0.9916149973869324 0.0 0.0 0.0 0.0 50.84244223865244 50.0 1.0 yes 4281 chrVII_399321r 13328 essential YGL055W 696 - TCAGCTCTAGCCTTGTATTT D|239|H D|239|N A|238|P A|238|T OLE1 OLEic acid requiring 510.0 0 0 0 0 -0.08764761130838364 P21147 0.965224027633667 0.97645902633667 0.9770879745483398 0.9687960147857666 0.008068772964179516 0.2215634435415268 0.03389102593064308 0.5748153328895569 52.03955123493376 40.0 1.0 no 4282 chrVII_399349r 13329 essential YGL055W 724 - GGTCCAATCATCAGTCATAT W|247|C W|247|* W|247|S W|247|* OLE1 OLEic acid requiring 510.0 0 0 0 0 -0.12625154208087416 P21147 0.9208570122718812 0.9205849766731262 0.05802518501877785 0.4894081354141235 47.83199948433901 40.0 1.0 no 4283 chrVII_399423 13331 essential YGL055W 795 + GTCATTCCAACTCTTATCTG silent|GTC>GTG|V|266 silent|GTC>GTT|V|266 P|268|A P|268|S OLE1 OLEic acid requiring 510.0 0 0 0 0 -0.11165896920011706 P21147 1.0004199743270874 0.9926369786262512 0.0 0.0 46.583226160241786 40.0 1.0 no 4284 chrVII_399447 13332 essential YGL055W 819 + TACTTTTTCAACGACTATAT Y|274|* silent|TAC>TAT|Y|274 OLE1 OLEic acid requiring 510.0 0 0 0 0 1.2926977846917578 P21147 37.05443346112281 25.0 1.0 no 4285 chrVII_399531 13334 essential YGL055W 903 + AACTCCTTGGCTCATTACAT N|302|K silent|AAC>AAT|N|302 S|303|C S|303|F OLE1 OLEic acid requiring 510.0 0 0 0 0 -2.580187101941624 P21147 0.9148370027542114 0.9879119992256165 0.9685909748077391 0.0 0.0 0.0 48.50058864348239 40.0 1.0 yes 4286 chrVII_399650r 13339 essential YGL055W 1025 - TAGCGTTTCTGTAATCAGTT A|348|P A|348|T OLE1 OLEic acid requiring 510.0 0 1 0 0 -0.4553338531602179 P21147 0.9770879745483398 0.9687960147857666 0.010848168283700943 0.0076537542045116425 45.07617458921475 35.0 1.0 no 4287 chrVII_399708 13342 essential YGL055W 1080 + ATCTATTTGACTTCTTTAGT I|361|M silent|ATC>ATT|I|361 OLE1 OLEic acid requiring 510.0 0 0 0 0 -0.13850747618523224 P21147 0.936680018901825 0.006958179175853729 40.74529952801959 25.0 1.0 no 4288 chrVII_410540 13346 essential YGL048C 727 - TTCATCCATAAAGATAATTG E|249|Q E|249|K D|248|H D|248|N RPT6 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 405.0 0 0 0 0 -6.573241928686921 Q01939 0.0 0.0 0.0 0.0 0.6863999962806702 0.8772666454315186 34.39730725992928 25.0 0.0 yes 4289 chrVII_410545r 13347 essential YGL048C 719 + TGCTCCCTCAATTATCTTTA A|241|G A|241|V P|242|A P|242|S RPT6 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 405.0 0 0 0 0 0.30594517278637184 Q01939 0.15630367398262024 0.11668919026851655 0.3932651877403259 0.03628362342715264 0.2865599989891052 1.6942399740219116 48.46703233567234 35.0 0.0 no 4290 chrVII_410575 13348 essential YGL048C 692 - TAGCCATCACAAACAGCTCA A|237|P A|237|T M|236|I M|236|I RPT6 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 405.0 0 0 0 0 -0.16535018577429855 Q01939 0.0 0.0 0.09449589252471924 0.09449589252471924 0.1393200010061264 0.1393200010061264 0.6183333396911621 0.6183333396911621 48.049963864606134 45.0 0.0 no 4291 chrVII_410578r 13349 essential YGL048C 686 + GGTCCGTGAGCTGTTTGTGA silent|GTC>GTG|V|230 silent|GTC>GTT|V|230 R|231|G R|231|C RPT6 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 405.0 0 0 0 0 0.23775260697758915 Q01939 0.001509036053903401 0.000178707399754785 56.91759632085024 55.00000000000001 0.0 no 4292 chrVII_410610r 13352 essential YGL048C 654 + GTACAAAAGTATATCGGCGA Q|220|E Q|220|* RPT6 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 405.0 0 1 0 0 -1.007647876441576 Q01939 0.18529435992240906 -0.1225999966263771 40.88497570338365 40.0 0.0 no 4293 chrVII_410678 13355 essential YGL048C 589 - TGCGACAGCTCTTGCCAATA A|203|P A|203|T V|202|L V|202|I RPT6 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 405.0 0 0 0 0 -0.4235726975100017 Q01939 0.0033722217194736004 0.002557089086622 0.00907929986715317 0.20530638098716736 7.878419876098633 3.1312201023101807 52.07338302902043 50.0 0.0 no 4294 chrVII_410839r 13362 essential YGL048C 425 + TCCTGATTCCACATACGATA P|143|R P|143|L P|143|A P|143|S RPT6 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 405.0 0 0 0 0 -0.4481759635265336 Q01939 0.2744967341423035 0.12521351873874664 0.8834646344184875 0.4728262424468994 -0.4172666072845459 -1.1480000019073486 0.2532000243663788 0.7054666876792908 46.892123407683364 40.0 0.0 no 4295 chrVII_410872 13364 essential YGL048C 395 - CCATCATCAACGAAACTAGT M|138|I M|138|I M|137|I M|137|I RPT6 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 405.0 0 0 0 0 -0.07831142371599975 Q01939 0.17807365953922272 0.17807365953922272 0.004609466530382633 0.004609466530382633 0.7051600217819214 0.7051600217819214 1.4896399974822998 1.4896399974822998 2.091900110244751 2.091900110244751 0.3145333230495453 0.3145333230495453 41.82929632165616 40.0 0.0 no 4296 chrVII_410872r 13365 essential YGL048C 392 + CCCACTAGTTTCGTTGATGA P|132|R P|132|L P|132|A P|132|S RPT6 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 405.0 0 0 0 0 -0.3717941642678929 Q01939 0.00233063125051558 0.003081208094954491 0.15629097819328308 0.03343552350997925 50.387918723232595 45.0 0.0 no 4297 chrVII_410939r 13367 essential YGL048C 325 + CATCTCAAAGAGTTTGTCTA S|110|C S|110|F Q|111|E Q|111|* RPT6 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 405.0 0 0 0 0 0.1531472660773467 Q01939 0.0017991733038797977 0.0012407220201566815 0.41307365894317627 41.577243440646896 35.0 0.0 no 4298 chrVII_410971r 13368 essential YGL048C 293 + TGCAAAAGATATAAACGTGA A|99|G A|99|V RPT6 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 405.0 0 1 0 0 0.9047647111082692 Q01939 0.4705917239189148 0.2630579173564911 33.693082438083245 30.0 0.0 no 4299 chrVII_411013r 13370 essential YGL048C 251 + TCTCGTTAAAGTGCAACCTG silent|CTC>CTG|L|85 silent|CTC>CTT|L|85 L|85|V L|85|F RPT6 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 405.0 0 0 0 1 -0.01699732776659679 Q01939 0.5067284107208252 0.006351244170218706 45.516127012136224 45.0 0.0 no 4300 chrVII_411012r 13371 essential YGL048C 252 + CTCGTTAAAGTGCAACCTGA silent|CTC>CTG|L|85 silent|CTC>CTT|L|85 RPT6 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 405.0 0 0 0 0 -0.11383261122921835 Q01939 45.70925005829406 45.0 0.0 no 4301 chrVII_411063 13373 essential YGL048C 204 - ACTTCACCCACATAAGATCC V|75|L V|75|I E|74|Q E|74|K RPT6 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 405.0 0 0 0 0 -1.2023959533163928 Q01939 0.09686465561389923 0.09937682002782823 0.07800406217575072 0.05192683637142181 49.09248019060993 45.0 0.0 no 4302 chrVII_411081r 13374 essential YGL048C 183 + CTGCGTCTATTACAGGAACC R|63|G R|63|C L|64|V silent|CTA>TTA|L|64 RPT6 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 405.0 0 0 0 0 -0.30160802939009 Q01939 0.10710744559764862 0.008311158046126366 0.5502762794494629 48.49463421202131 50.0 0.0 no 4303 chrVII_411109r 13376 essential YGL048C 155 + TGACAAAGTACGTTTTATCA D|53|E silent|GAC>GAT|D|53 RPT6 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 405.0 0 0 0 0 -0.4990086522606337 Q01939 0.7727510929107666 38.09412372011707 30.0 0.0 no 4304 chrVII_411572 13380 essential YGL047W 20 + GGCTCTTTTTGTTACGTGTG A|8|G A|8|V L|9|V L|9|F ALG13 Asparagine-Linked Glycosylation 202.0 0 0 0 0 -1.1484889874940163 P53178 0.9484469890594482 0.9504740238189696 0.9512209892272948 0.9587849974632264 0.019860101863741875 0.01981749944388866 0.7328346967697144 0.10538700968027116 1.4043999910354614 0.7481600046157837 2.048919916152954 8.341059684753418 0.5248000025749207 0.9193999767303468 50.216411003501605 45.0 1.0 no 4305 chrVII_411673 13384 essential YGL047W 121 + TACGTCTAATCATTCAGTTT R|42|G R|42|C L|43|V silent|CTA>TTA|L|43 ALG13 Asparagine-Linked Glycosylation 202.0 0 0 0 0 0.06217111327075489 P53178 0.8994590044021606 0.8926740288734436 0.9512209892272948 0.05040653422474861 0.008208687417209148 1.0 1.520699977874756 0.2359199970960617 1.5330400466918943 41.44688850883267 30.0 1.0 no 4306 chrVII_411809r 13391 essential YGL047W 260 - CCTTTAATTTCCCGTTCATC K|93|N silent|AAG>AAA|K|93 ALG13 Asparagine-Linked Glycosylation 202.0 0 0 0 0 -0.4641211448346146 P53178 0.9355990290641784 0.07392263412475586 0.864080011844635 49.648807904018895 40.0 1.0 no 4307 chrVII_411891 13395 essential YGL047W 339 + GTCATATCACACGCTGGAAC silent|GTC>GTG|V|114 silent|GTC>GTT|V|114 ALG13 Asparagine-Linked Glycosylation 202.0 0 0 0 0 0.13002568341977885 P53178 47.17168707912077 50.0 1.0 no 4308 chrVII_411945r 13397 essential YGL047W 396 - TCGTTTACGCAAACTATCAA D|139|H D|139|N ALG13 Asparagine-Linked Glycosylation 202.0 0 0 0 0 -0.18557460325973216 P53178 0.9486550092697144 0.956179976463318 0.19587424397468567 0.2415632307529449 0.4246599972248077 0.1447799950838089 40.421878097880146 35.0 1.0 no 4309 chrVII_416535 13403 essential YGL044C 482 - CGCTCGATATCATCATAGCA S|167|T S|167|N silent|TCG>TCC|S|166 silent|TCG>TCA|S|166 0 0 0 0 0.035389241171167575 P25299 0.9512869715690612 0.9536849856376648 0.5292079448699951 0.45623633265495295 0.5414400100708008 0.3652999997138977 47.75692374076914 45.0 0.0 no 4310 chrVII_416797 13412 essential YGL044C 220 - ATTCAAATTACGTACTGCGC L|79|F silent|TTG>TTA|L|79 0 0 0 0 0.012471549712488485 P25299 0.9587849974632264 0.0 2.1359400749206543 43.002274650114714 40.0 0.0 no 4311 chrVII_416857 13414 essential YGL044C 160 - CCCTTTCGACCTACCAGTTT G|60|R G|60|R G|60|A G|60|E 0 0 0 0 -0.9602393847177816 P25299 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.0 0.0 0.0 0.0 6.901080131530763 6.901080131530763 3.8559200763702393 6.415019989013673 56.36914210423835 50.0 0.0 no 4312 chrVII_416858 13415 essential YGL044C 159 - CCTTTCGACCTACCAGTTTG G|60|R G|60|R silent|TCG>TCC|S|58 silent|TCG>TCA|S|58 0 0 0 0 0.7481013161067487 P25299 0.941340982913971 0.941340982913971 0.0 0.0 6.901080131530763 6.901080131530763 52.78988822257094 50.0 0.0 no 4313 chrVII_419805 13427 essential YGL040C 731 - TTTCCAACGCCCTACGTGCC E|250|Q E|250|K L|249|F silent|TTG>TTA|L|249 HEM2 HEMe biosynthesis 342.0 0 1 0 0 -1.1403289815226374 P05373 0.956179976463318 0.9475290179252625 0.9587849974632264 0.593060314655304 0.9010308384895324 0.6877661347389221 -0.20951999723911285 -0.573199987411499 3.747100114822388 58.711916426069926 60.0 0.0 no 4314 chrVII_419867r 13435 essential YGL040C 666 + GCTTGTTCAGCTCCTTCGAA A|223|G A|223|V HEM2 HEMe biosynthesis 342.0 0 0 0 0 0.4102381450500773 P05373 0.9484469890594482 0.9504740238189696 0.0031928305979818106 0.28035664558410645 0.7826600074768066 3.860939979553223 1.6365599632263184 0.8763399720191956 54.61015808503515 50.0 0.0 no 4315 chrVII_419877 13436 essential YGL040C 659 - GAGCTGAACAAGCAGCATCA A|226|P A|226|T HEM2 HEMe biosynthesis 342.0 0 0 0 0 0.4326932146212487 P05373 0.9573720097541808 0.9523990154266356 0.03343590721487999 0.292012631893158 -0.4725199937820434 0.7898799777030945 -1.1949399709701538 0.4811399877071381 48.20591645053605 50.0 0.0 no 4316 chrVII_419917 13439 essential YGL040C 619 - ACCGCTAAACTTAGCTGCAT G|213|R G|213|S G|213|A G|213|D HEM2 HEMe biosynthesis 342.0 0 1 0 0 -0.4704215818235177 P05373 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.004149500746279955 1.0 0.04398125410079956 0.009351702407002449 4.813199996948242 3.6791799068450928 3.0548200607299805 2.520159959793091 48.78770248269791 45.0 0.0 no 4317 chrVII_420111 13447 essential YGL040C 425 - CATCGTATAGAACCCCGCAA D|148|H D|148|N HEM2 HEMe biosynthesis 342.0 0 1 0 0 0.5282329838968747 P05373 0.9486550092697144 0.956179976463318 0.03816448524594307 0.2222483456134796 0.15904000401496887 -0.005919999908655882 0.30017998814582825 0.21330000460147855 49.81062722180889 50.0 0.0 no 4318 chrVII_420134r 13451 essential YGL040C 399 + CTCTGTGAATACACTTCTCA silent|CTC>CTG|L|134 silent|CTC>CTT|L|134 HEM2 HEMe biosynthesis 342.0 0 0 0 0 0.22664192098328045 P05373 44.88914782618781 40.0 0.0 no 4319 chrVII_420164 13452 essential YGL040C 372 - TCGCAAATAATATACAGTTC C|130|S C|130|Y D|131|H D|131|N HEM2 HEMe biosynthesis 342.0 0 1 0 0 0.044886579584151036 P05373 0.9421560168266296 0.9290120005607604 0.9486550092697144 0.956179976463318 0.012431912124156952 0.0011767125688493252 0.0 0.0 1.0016599893569946 14.197440147399902 4.725279808044434 1.8207199573516848 36.1930961930679 30.0 0.0 no 4320 chrVII_420165 13453 essential YGL040C 371 - CGCAAATAATATACAGTTCA C|130|S C|130|Y HEM2 HEMe biosynthesis 342.0 0 1 0 0 -0.3336782271418771 P05373 0.9421560168266296 0.9290120005607604 0.012431912124156952 0.0011767125688493252 1.0016599893569946 14.197440147399902 36.72189306361645 30.0 0.0 no 4321 chrVII_420227r 13457 essential YGL040C 306 + ACAGCGGCTGACGATCCTGC T|103|R T|103|I A|104|G A|104|V HEM2 HEMe biosynthesis 342.0 0 0 0 0 1.1991937129659418 P05373 0.9476869702339172 0.9472420215606691 0.9484469890594482 0.9504740238189696 0.006476808339357376 0.007316987495869398 0.4702858328819275 0.4375196397304535 -1.307479977607727 -0.028240000829100612 1.0565199851989746 0.682699978351593 1.385599970817566 0.8898199796676636 57.50282462605776 65.0 0.0 no 4322 chrVII_420236 13458 essential YGL040C 300 - TCGTCAGCCGCTGTACCCAC D|107|H D|107|N D|106|H D|106|N HEM2 HEMe biosynthesis 342.0 0 0 0 0 -1.2451310635522106 P05373 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.0985124260187149 0.5215409398078918 0.0142478309571743 0.05574451759457588 0.7019000053405762 0.3038400113582611 3.2016599178314213 -0.02711999975144863 61.69209651032793 65.0 0.0 no 4323 chrVII_420318r 13466 essential YGL040C 215 + AGACTACTTAAAGCCATTAG D|73|E silent|GAC>GAT|D|73 Y|74|* silent|TAC>TAT|Y|74 HEM2 HEMe biosynthesis 342.0 0 0 0 0 1.1312412291293068 P05373 0.9532920122146606 1.0 -0.34731999039649963 39.887332867849686 35.0 0.0 no 4324 chrVII_420353 13469 essential YGL040C 183 - ACACCGATTCTATTGATATT G|67|A G|67|D V|68|L V|68|I HEM2 HEMe biosynthesis 342.0 0 0 0 0 -2.5094718911967995 P05373 0.9499930143356324 0.9446240067481996 0.9539830088615416 0.9574310183525084 0.008067908696830273 0.022859247401356697 0.29418978095054626 0.5117121934890747 6.566539764404298 29.185199737548828 -1.132699966430664 -1.3622399568557741 -1.4993400573730469 -1.294100046157837 41.50076049847849 30.0 0.0 yes 4325 chrVII_420383 13470 essential YGL040C 153 - TCAATTTCAGTAAAGTCATC D|58|H D|58|N HEM2 HEMe biosynthesis 342.0 0 0 0 0 0.2064362298903252 P05373 0.9486550092697144 0.956179976463318 0.13736632466316226 0.3297141194343567 0.005719999782741071 0.013779999688267708 37.375503780490476 30.0 0.0 no 4326 chrVII_420494r 13472 essential YGL040C 39 + ATCTCATCTGTTCTAGCAGG I|14|M silent|ATC>ATT|I|14 S|15|* S|15|L HEM2 HEMe biosynthesis 342.0 0 0 0 0 -1.0898937732086302 P05373 0.9598389863967896 0.9298099875450134 0.030926413834095 0.08640511333942412 -0.2428199946880341 -0.403439998626709 0.178739994764328 0.035659998655319214 0.1908400058746338 -0.30866000056266785 50.25280356110943 45.0 0.0 no 4327 chrVII_439497 13476 essential YGL030W 179 + CGCTATGTTGTCCAAGACTA A|61|G A|61|V RPL30 Ribosomal Protein of the Large subunit 105.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.5120272814921065 P14120 48.220248912107714 45.0 1.0 no 4328 chrVII_452448 13481 essential YGL022W 44 + CCTCAAGCTCGTCATCTTCG silent|CTC>CTG|L|16 silent|CTC>CTT|L|16 L|16|V L|16|F STT3 STaurosporine and Temperature sensitive 718.0 0 0 0 0 -1.0259654780950551 P39007 0.1592085063457489 0.1750391125679016 53.4253625285196 55.00000000000001 1.0 no 4329 chrVII_452486r 13485 essential YGL022W 85 - TGCAAACAAACGTGATGATA A|35|P A|35|T L|33|F silent|TTG>TTA|L|33 STT3 STaurosporine and Temperature sensitive 718.0 0 0 0 0 0.9509811487730552 P39007 0.013118606992065908 0.01200495008379221 0.006574262399226427 36.94780861545678 35.0 1.0 no 4330 chrVII_452632r 13490 essential YGL022W 231 - CCTCCAGTAACCCTTCCGAG G|83|A G|83|E G|84|R G|84|R STT3 STaurosporine and Temperature sensitive 718.0 0 0 0 0 -5.93746261140925 P39007 0.0 0.0 0.0049586850218474865 0.0049586850218474865 58.05039157774382 60.0 1.0 yes 4331 chrVII_452726r 13500 essential YGL022W 325 - ACAAACGTTTCTGATGTCAA C|115|S C|115|Y V|114|L V|114|I STT3 STaurosporine and Temperature sensitive 718.0 0 0 0 0 0.3149149418496008 P39007 0.0 0.0 0.012257077731192112 0.4101183414459229 40.188075151135884 35.0 1.0 no 4332 chrVII_452863r 13504 essential YGL022W 462 - ACTGATCTAGATATATAACC V|161|L V|161|M R|159|T R|159|K STT3 STaurosporine and Temperature sensitive 718.0 0 0 0 0 -0.13684450585481694 P39007 0.005035914480686189 0.00166201195679605 0.0 0.0 37.3734911404041 30.0 1.0 no 4333 chrVII_452934 13507 essential YGL022W 530 + CACTTTCATGTTTTGGATTA T|178|S T|178|I F|179|L silent|TTC>TTT|F|179 STT3 STaurosporine and Temperature sensitive 718.0 0 0 0 0 -0.5123172282571188 P39007 0.06496468931436539 0.0032207819167524576 0.010301612317562105 42.13101502705291 30.0 1.0 no 4334 chrVII_452958r 13508 essential YGL022W 557 - GCATGATAGAGCCAGTCTTT M|192|I M|192|I STT3 STaurosporine and Temperature sensitive 718.0 0 0 0 0 0.6023778332508348 P39007 0.12063620984554292 0.12063620984554292 51.27272671152792 45.0 1.0 no 4335 chrVII_452994 13509 essential YGL022W 590 + AGCTTTATTCTACTTCTACA A|198|G A|198|V STT3 STaurosporine and Temperature sensitive 718.0 0 0 0 0 0.08175494456971992 P39007 0.0887545645236969 0.012497358024120329 43.707945695775614 30.0 1.0 no 4336 chrVII_453063r 13517 essential YGL022W 662 - TCAAAATCAGCAAAAAGACA L|227|F silent|TTG>TTA|L|227 STT3 STaurosporine and Temperature sensitive 718.0 0 0 0 0 0.9174703998379148 P39007 0.21351784467697146 32.88573352307219 30.0 1.0 no 4337 chrVII_453058r 13518 essential YGL022W 657 - ATCAGCAAAAAGACATGGAG silent|CTG>CTC|L|225 silent|CTG>CTA|L|225 L|224|F silent|TTG>TTA|L|224 STT3 STaurosporine and Temperature sensitive 718.0 0 0 0 0 -1.5043850675110817 P39007 0.15406052768230438 37.65320448673367 40.0 1.0 no 4338 chrVII_453067 13519 essential YGL022W 663 + GTCTTTTTGCTGATTTTGAT silent|GTC>GTG|V|222 silent|GTC>GTT|V|222 STT3 STaurosporine and Temperature sensitive 718.0 0 0 0 0 0.28401904852011284 P39007 44.21718970634789 30.0 1.0 no 4339 chrVII_453151 13521 essential YGL022W 747 + TCCATGCAGATCCCATTTGT silent|TCC>TCG|S|250 silent|TCC>TCT|S|250 S|250|C S|250|F STT3 STaurosporine and Temperature sensitive 718.0 0 0 0 0 -3.68281726267556 P39007 0.05713919922709465 0.0053671360947191715 54.60947802597423 45.0 1.0 yes 4340 chrVII_453183 13523 essential YGL022W 779 + TATCAGGTCTAACGACCACA I|261|M silent|ATC>ATT|I|261 STT3 STaurosporine and Temperature sensitive 718.0 0 0 0 0 -0.459553615779027 P39007 0.0073981909081339845 46.85477196083042 45.0 1.0 no 4341 chrVII_453339 13528 essential YGL022W 935 + ACTTTCTGCCTTGACCTATA L|313|V L|313|F S|314|C S|314|F STT3 STaurosporine and Temperature sensitive 718.0 0 0 0 0 1.0416909279138844 P39007 0.7702914476394653 0.7080003023147583 0.07093930244445801 0.5938798189163208 50.650851691037985 40.0 1.0 no 4342 chrVII_453341 13529 essential YGL022W 937 + TTTCTGCCTTGACCTATATG S|314|C S|314|F A|315|G A|315|V STT3 STaurosporine and Temperature sensitive 718.0 0 0 0 0 -0.11807074951560916 P39007 0.07093930244445801 0.5938798189163208 0.4125727415084839 0.6570761203765869 48.317754392602126 40.0 1.0 no 4343 chrVII_453347r 13530 essential YGL022W 946 - AATCAACCCCATATAGGTCA L|321|F silent|TTG>TTA|L|321 silent|GGG>GGC|G|320 silent|GGG>GGA|G|320 STT3 STaurosporine and Temperature sensitive 718.0 0 0 0 0 -0.3890331550050937 P39007 0.6816302537918091 47.756639028138295 40.0 1.0 no 4344 chrVII_453449 13532 essential YGL022W 1045 + CCGAACATCAACCCGTTTCG silent|TCC>TCG|S|349 silent|TCC>TCT|S|349 H|351|D H|351|Y STT3 STaurosporine and Temperature sensitive 718.0 0 0 0 0 0.5438170783829821 P39007 0.004157560877501965 0.002797172637656331 50.136984176323146 55.00000000000001 1.0 no 4345 chrVII_453580 13536 essential YGL022W 1176 + GTTCTGTGTTCGTACTTTGC L|394|V silent|CTG>TTG|L|394 STT3 STaurosporine and Temperature sensitive 718.0 0 0 0 0 0.5581583151731998 P39007 0.5363404154777527 51.394729961879136 45.0 1.0 no 4346 chrVII_453588 13537 essential YGL022W 1184 + TTCGTACTTTGCCGGTGTTA S|396|W S|396|L Y|397|* silent|TAC>TAT|Y|397 STT3 STaurosporine and Temperature sensitive 718.0 0 0 0 0 -0.3285357210751529 P39007 0.15123224258422852 0.4520122408866882 52.32334746050634 45.0 1.0 no 4347 chrVII_453720 13541 essential YGL022W 1316 + CATCAAACCTGCGGCACTAC I|440|M silent|ATC>ATT|I|440 STT3 STaurosporine and Temperature sensitive 718.0 0 1 0 0 0.6398907527921673 P39007 0.1030668392777443 49.829766796054116 55.00000000000001 1.0 no 4348 chrVII_453795r 13542 essential YGL022W 1394 - TTCTTGTTACCCAAGTAGAA R|471|T R|471|K STT3 STaurosporine and Temperature sensitive 718.0 0 0 0 0 -0.4592957564545795 P39007 0.09830224514007567 0.054127153009176254 -4.611400127410889 0.11460000276565553 -1.3167999982833862 0.1387999951839447 44.48491812801392 35.0 1.0 no 4349 chrVII_453844 13543 essential YGL022W 1440 + TTGCCATCACAAACCCCAGA P|482|A P|482|S P|482|R P|482|L STT3 STaurosporine and Temperature sensitive 718.0 0 0 0 0 0.5302452759263642 P39007 1.0 0.8372612595558167 0.19681087136268616 0.06414962559938431 1.212000012397766 1.3708000183105469 2.513200044631958 1.0759999752044678 52.961269688099215 50.0 1.0 no 4350 chrVII_453857r 13546 essential YGL022W 1456 - CAACGCCAATTTACCATCTG silent|GCG>GCC|A|491 silent|GCG>GCA|A|491 A|491|P A|491|T STT3 STaurosporine and Temperature sensitive 718.0 0 0 0 0 0.8892167156484749 P39007 0.2030862867832184 0.3921926021575928 1.739199995994568 -0.07479999959468843 6.063000202178955 1.0820000171661377 46.15735779876508 45.0 1.0 no 4351 chrVII_453858r 13547 essential YGL022W 1457 - TCAACGCCAATTTACCATCT L|492|F silent|TTG>TTA|L|492 silent|GCG>GCC|A|491 silent|GCG>GCA|A|491 STT3 STaurosporine and Temperature sensitive 718.0 0 1 0 0 -0.5861844235121183 P39007 0.006054433528333902 -0.5848000049591064 -0.4359999895095825 47.09933495910201 40.0 1.0 no 4352 chrVII_453859r 13548 essential YGL022W 1458 - ATCAACGCCAATTTACCATC L|492|F silent|TTG>TTA|L|492 silent|GCG>GCC|A|491 silent|GCG>GCA|A|491 STT3 STaurosporine and Temperature sensitive 718.0 0 1 0 0 0.5043002035911173 P39007 0.006054433528333902 -0.5848000049591064 -0.4359999895095825 45.42980457020224 40.0 1.0 no 4353 chrVII_453966r 13553 essential YGL022W 1565 - TGTCTGCCATGCCACCAATT D|528|H D|528|N A|527|P A|527|T STT3 STaurosporine and Temperature sensitive 718.0 0 0 0 0 0.33976330259601634 P39007 0.005896504502743483 1.0 0.00639490969479084 0.0044474308378994465 -1.2236000299453735 -1.8766000270843504 8.622200012207031 0.5788000226020813 12.179800033569336 2.309000015258789 55.977708203276684 50.0 1.0 no 4354 chrVII_459296 13555 essential YGL018C 349 - ACCAGCTTCGTCGTCCATCT G|123|R G|123|S G|123|A G|123|D JAC1 J-type Accessory Chaperone 184.0 0 0 0 0 -0.7103629634093018 P53193 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.1831870973110199 0.2867065966129303 0.3439598083496094 0.5267640948295593 -1.1175400018692017 0.4308600127696991 -1.1242799758911133 -0.042440000921487815 59.1254142614352 55.00000000000001 0.0 no 4355 chrVII_459440r 13557 essential YGL018C 202 + CTCTCAAAGATCCCCTTAGA L|69|V L|69|F silent|CTC>CTG|L|69 silent|CTC>CTT|L|69 JAC1 J-type Accessory Chaperone 184.0 0 0 0 0 0.5772077666635583 P53193 0.9512209892272948 0.9587849974632264 0.0 0.0 2.330219984054565 10.89173984527588 49.53876732225446 45.0 0.0 no 4356 chrVII_459575 13561 essential YGL018C 70 - AGTCCAAATGGGTAGCTTTT W|29|C W|29|* W|29|S W|29|* JAC1 J-type Accessory Chaperone 184.0 0 0 0 0 -2.1268045496590053 P53193 0.8858469724655151 0.8858469724655151 0.009068314917385578 0.013028538785874844 2.486860036849976 4.089000225067139 2.7126760482788086 4.01281213760376 48.05301732555176 40.0 0.0 yes 4357 chrVII_474768 13566 essential YGL011C 460 - TGCAGGGTCAGTTTTGTAAA A|160|P A|160|T SCL1 Suppressor of Crl3 ts Lethality 252.0 0 0 0 0 -0.6799762084502068 P21243 0.8313930034637451 0.826898992061615 0.006712706293910742 0.0053348103538155564 1.3271199464797974 2.278019905090332 1.5609400272369385 2.607379913330078 2.7809948921203613 1.0426349639892578 46.22837037959 40.0 0.0 no 4358 chrVII_474914 13569 essential YGL011C 314 - TATCATAACCATATTTATAA D|111|H D|111|N SCL1 Suppressor of Crl3 ts Lethality 252.0 0 1 0 0 0.1411209317712414 P21243 0.7802879810333252 0.8044790029525757 0.02408468723297119 0.1831832230091095 0.020239999517798424 -0.2343199998140335 -0.041517004370689385 -0.17796100676059726 32.49085256036034 15.0 0.0 no 4359 chrVII_474889 13570 essential YGL011C 339 - CTCTTAGCCAATACATCGCA K|119|N silent|AAG>AAA|K|119 SCL1 Suppressor of Crl3 ts Lethality 252.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.7927646261741066 P21243 0.6967300176620483 0.022329632192850116 0.4526799917221069 1.4607900381088257 49.115736267693755 45.0 0.0 no 4360 chrVII_475115r 13575 essential YGL011C 110 + AACTAACATAAACTCACTAG T|38|S T|38|I N|39|K silent|AAC>AAT|N|39 SCL1 Suppressor of Crl3 ts Lethality 252.0 0 0 0 0 -0.1862721348882831 P21243 0.892274022102356 0.8796520233154297 0.8263450264930725 0.8949767351150513 0.20903077721595764 0.03387690335512161 -0.4781000018119812 -2.813699960708618 0.26513999700546265 -0.2305440008640289 33.2459236127051 30.0 0.0 no 4361 chrVII_475164 13576 essential YGL011C 64 - TACTTGATATAAACGACCCT V|28|L V|28|I SCL1 Suppressor of Crl3 ts Lethality 252.0 0 0 0 0 -1.0098333368842252 P21243 0.7981879711151123 0.8188930153846741 0.017707007005810738 0.3461788892745972 1.8777400255203247 0.8668199777603149 -0.8274000287055969 -0.7685999870300293 41.45019716619339 35.0 0.0 no 4362 chrVII_475180r 13578 essential YGL011C 45 + ATCACTATCTTTTCCCCCGA I|16|M silent|ATC>ATT|I|16 T|17|S T|17|I SCL1 Suppressor of Crl3 ts Lethality 252.0 0 0 0 0 0.3556180044319457 P21243 0.8870069980621338 0.868071973323822 0.8080989718437195 0.047611035406589515 0.09226207435131073 0.001769151305779815 -0.10524000227451323 0.7319999933242798 1.692620038986206 -0.19750000536441806 -0.26808667182922363 0.5288066864013672 0.5529666543006897 55.112890718573674 45.0 0.0 no 4363 chrVII_475181r 13579 essential YGL011C 44 + CATCACTATCTTTTCCCCCG I|16|M silent|ATC>ATT|I|16 T|17|S T|17|I SCL1 Suppressor of Crl3 ts Lethality 252.0 0 0 0 0 0.4828826021434442 P21243 0.8870069980621338 0.868071973323822 0.8080989718437195 0.047611035406589515 0.09226207435131073 0.001769151305779815 -0.10524000227451323 0.7319999933242798 1.692620038986206 -0.19750000536441806 -0.26808667182922363 0.5288066864013672 0.5529666543006897 55.10277395888079 50.0 0.0 no 4364 chrVII_494625 13583 no_effect YGL002W 108 + TCCAAAGACACCCTTTTAAA silent|TCC>TCG|S|37 silent|TCC>TCT|S|37 S|37|C S|37|F ERP6 Emp24p/Erv25p Related Protein 216.0 0 0 0 0 0.23057571120132425 P53198 0.945252001285553 0.9294660091400146 0.0690787062048912 0.043216511607170105 42.719877376205496 35.0 1.0 no 4365 chrVII_494694 13584 no_effect YGL002W 177 + CTTCCCAGTTATAATGACTA P|61|A P|61|S P|61|R P|61|L ERP6 Emp24p/Erv25p Related Protein 216.0 0 0 0 0 0.13541789017515438 P53198 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.5121133923530579 0.2663574814796448 0.0204378254711628 0.02368052490055561 44.41862829186107 35.0 1.0 no 4366 chrVII_494738 13586 no_effect YGL002W 221 + AGTCTTTGATAATAATCATA silent|GTC>GTG|V|75 silent|GTC>GTT|V|75 ERP6 Emp24p/Erv25p Related Protein 216.0 0 0 0 0 -0.014299975320716226 P53198 33.78966118723082 20.0 1.0 no 4367 chrVII_494789 13589 no_effect YGL002W 272 + TGACTTCAGCTTTCTAGCTT D|92|E silent|GAC>GAT|D|92 F|93|L silent|TTC>TTT|F|93 ERP6 Emp24p/Erv25p Related Protein 216.0 0 0 0 0 0.38964376356068997 P53198 0.9532920122146606 0.9387490153312684 1.0 0.3985530734062195 49.79476362628958 40.0 1.0 no 4368 chrVII_494869r 13595 no_effect YGL002W 355 - TTCGATTTCTAACTTTGTTT E|125|Q E|125|K ERP6 Emp24p/Erv25p Related Protein 216.0 0 0 0 0 0.048444103810455504 P53198 0.956179976463318 0.9475290179252625 0.15670481324195862 0.0331948846578598 39.92002604967701 25.0 1.0 no 4369 chrVII_495699 13597 essential YGL001C 784 - ATCTGCCTTCCACACAGTAC D|268|H D|268|N A|267|P A|267|T ERG26 ERGosterol biosynthesis 349.0 0 0 0 0 -1.1026348401422066 P53199 0.5410826206207275 0.30973803997039795 0.22364704310894007 0.4284081161022186 9.712599754333496 2.621999979019165 54.0274305073246 50.0 0.0 no 4370 chrVII_495705 13598 essential YGL001C 778 - CTTCCACACAGTACGGGCCA W|265|C W|265|* W|265|S W|265|* ERG26 ERGosterol biosynthesis 349.0 0 0 0 0 -2.3735496648124883 P53199 0.001974879764020443 0.0027221080381423235 1.531999945640564 1.5221999883651731 57.78096367570453 60.0 0.0 yes 4371 chrVII_495929 13605 essential YGL001C 554 - GTACTAATTGCCTATCACCT V|191|L V|191|I ERG26 ERGosterol biosynthesis 349.0 0 0 0 0 0.4053823733279993 P53199 0.1452394425868988 0.8933663964271545 48.77825984196227 40.0 0.0 no 4372 chrVII_495952r 13608 essential YGL001C 528 + CTTCGTCCAGCTGGTATTTT R|178|G R|178|C P|179|A P|179|S ERG26 ERGosterol biosynthesis 349.0 0 0 0 0 -2.004137703785692 P53199 0.0 0.0 0.12886932492256165 0.055386673659086234 53.21014156202546 45.0 0.0 no 4373 chrVII_496052 13613 essential YGL001C 431 - ACGCATCCATAGGAACTTCT A|150|P A|150|T silent|GCG>GCC|A|150 silent|GCG>GCA|A|150 ERG26 ERGosterol biosynthesis 349.0 0 1 0 0 0.5291642624075722 P53199 0.2258466333150864 0.38541564345359797 0.06859999895095825 2.051399946212769 48.77796985271971 45.0 0.0 no 4374 chrVII_496058r 13615 essential YGL001C 422 + GCCAATCCCAGAAGTTCCTA P|142|R P|142|L P|142|A P|142|S ERG26 ERGosterol biosynthesis 349.0 0 0 0 0 -2.1333319082469933 P53199 0.007939680479466915 0.0056182267144322395 0.02448433823883533 0.015043360181152819 54.76550773688013 50.0 0.0 yes 4375 chrVII_496080r 13616 essential YGL001C 400 + TGCACAATGCAGACGAAACC H|135|D H|135|Y H|135|Q silent|CAC>CAT|H|135 ERG26 ERGosterol biosynthesis 349.0 0 0 0 0 -0.9727276043513664 P53199 0.04152827709913254 0.10649719089269638 0.33816105127334595 -0.9031999707221984 -1.753000020980835 -0.8542000055313109 44.76046345048326 50.0 0.0 no 4376 chrVII_496110r 13617 essential YGL001C 370 + CTGCTGGTGTTATTTTTAAT A|125|G A|125|V ERG26 ERGosterol biosynthesis 349.0 0 0 0 0 -1.0134257312879769 P53199 0.026087427511811256 0.008353426121175291 -0.06440000236034392 4.8368000984191895 42.54006074790328 30.0 0.0 no 4377 chrVII_496169 13618 essential YGL001C 314 - TGCACATATCTATCACGTTA C|111|S C|111|Y M|110|I M|110|I ERG26 ERGosterol biosynthesis 349.0 0 0 0 0 0.828807042775231 P53199 0.05284927040338516 0.003769053844735026 0.15057887136936188 0.15057887136936188 0.3741999864578247 19.291200637817386 2.669800043106079 2.669800043106079 43.83343051213871 35.0 0.0 no 4378 chrVII_496204 13620 essential YGL001C 279 - TTCACTATGTCATAAATATC silent|GTG>GTC|V|99 silent|GTG>GTA|V|99 V|99|L V|99|M ERG26 ERGosterol biosynthesis 349.0 0 0 0 0 0.07521321433043675 P53199 0.0 0.0 -1.1308000087738037 -0.9214000105857848 34.999416052521724 25.0 0.0 no 4379 chrVII_496222 13621 essential YGL001C 261 - TCTGGATTTTGACCATGCAT D|94|H D|94|N ERG26 ERGosterol biosynthesis 349.0 0 0 0 0 0.4385006710211262 P53199 0.04682458937168121 0.18432463705539706 48.15660779467038 40.0 0.0 no 4380 chrVII_496357 13622 essential YGL001C 126 - AACTGTTTTGAAAGTTTTTC Q|48|H silent|CAG>CAA|Q|48 ERG26 ERGosterol biosynthesis 349.0 0 1 0 0 0.8603566239529125 P53199 0.5426144003868103 35.919905758969385 25.0 0.0 no 4381 chrVII_498921 13625 essential YGR002C 966 - TGCTTCATCCAAGGATTTTC K|328|N silent|AAG>AAA|K|328 M|327|I M|327|I SWC4 SWr Complex 476.0 0 0 0 0 0.46951792729263997 P53201 0.13300088047981262 0.3870447874069214 0.3870447874069214 47.37275893601525 40.0 0.0 no 4382 chrVII_498922 13627 essential YGR002C 965 - GCTTCATCCAAGGATTTTCA K|328|N silent|AAG>AAA|K|328 M|327|I M|327|I SWC4 SWr Complex 476.0 0 0 0 0 -2.9297416950174364 P53201 0.13300088047981262 0.3870447874069214 0.3870447874069214 48.70688016956165 40.0 0.0 yes 4383 chrVII_498998 13628 essential YGR002C 889 - TAACTGAGACATTCCCTGAG Q|302|H silent|CAG>CAA|Q|302 SWC4 SWr Complex 476.0 0 0 0 0 -0.3185408369261038 P53201 0.034686129540205 45.63781551837138 45.0 0.0 no 4384 chrVII_499012r 13630 essential YGR002C 872 + TACACAATACCTTACCTCTC T|292|R T|292|I Q|293|E Q|293|* SWC4 SWr Complex 476.0 0 0 0 0 -0.31412327676846513 P53201 0.01583891361951828 0.01626594550907612 0.04678377509117127 45.81097348128049 40.0 0.0 no 4385 chrVII_499011r 13631 essential YGR002C 873 + ACACAATACCTTACCTCTCA Q|293|E Q|293|* T|292|R T|292|I SWC4 SWr Complex 476.0 0 0 0 0 0.3966602998723943 P53201 0.04678377509117127 0.01583891361951828 0.01626594550907612 47.612685500960986 40.0 0.0 no 4386 chrVII_499082 13632 essential YGR002C 805 - TCTTTCTGCAAGTGTTCTCT R|275|T R|275|K E|274|Q E|274|K SWC4 SWr Complex 476.0 0 0 0 0 -0.9013897101630424 P53201 0.0 0.0 0.0 0.0 50.39555327326252 40.0 0.0 no 4387 chrVII_499333 13633 essential YGR002C 554 - AACTGTATCTGTCAAAGATC S|191|T S|191|N SWC4 SWr Complex 476.0 0 0 0 0 1.259696598866041 P53201 0.12013426423072815 0.6376346349716187 38.63186123849732 35.0 0.0 no 4388 chrVII_499435r 13636 essential YGR002C 449 + AAACTTTACTAATGAAAAGA N|151|K silent|AAC>AAT|N|151 SWC4 SWr Complex 476.0 0 1 0 0 0.5594422218235886 P53201 0.4180697798728943 28.603158146048884 20.0 0.0 no 4389 chrVII_499531r 13639 essential YGR002C 353 + ATCTATTCCATCATTCACCA S|119|C S|119|F SWC4 SWr Complex 476.0 0 0 0 0 -0.15708534966402354 P53201 0.05083119124174118 0.042230900377035134 48.3826926235671 35.0 0.0 no 4390 chrVII_499618r 13642 essential YGR002C 266 + GACTCTGCGTCATTGGGTCA T|90|S T|90|I L|91|V silent|CTG>TTG|L|91 SWC4 SWr Complex 476.0 0 0 0 0 -0.8067577406846065 P53201 0.7130329608917236 0.1892381012439728 0.023730486631393436 55.625291477762225 55.00000000000001 0.0 no 4391 chrVII_499624r 13643 essential YGR002C 260 + CTCTGTGACTCTGCGTCATT S|88|C S|88|F SWC4 SWr Complex 476.0 0 0 0 0 0.4395877970536172 P53201 0.17635196447372434 0.6761817932128906 53.0467126877 50.0 0.0 no 4392 chrVII_499719 13646 essential YGR002C 168 - TTTCCAGACTTAATAACAAC G|62|A G|62|E G|62|R G|62|R SWC4 SWr Complex 476.0 0 0 0 0 1.027266431541682 P53201 0.9191245436668396 1.0 0.5402931571006775 0.5402931571006775 36.69341577706422 30.0 0.0 no 4393 chrVII_505018r 13656 essential YGR005C 819 + AACTCGAATTTCTTGAAAGT N|274|K silent|AAC>AAT|N|274 S|275|W S|275|L TFG2 Transcription Factor G 400.0 0 1 0 0 -0.7997802936164788 P41896 0.9439849853515624 0.9288619756698608 0.9298099875450134 0.2529025673866272 0.0023777184542268515 0.012244882062077522 36.72205968110745 30.0 0.0 no 4394 chrVII_505032 13657 essential YGR005C 808 - ATTCGAGTTGTCTGACCTCA silent|TCG>TCC|S|275 silent|TCG>TCA|S|275 TFG2 Transcription Factor G 400.0 0 0 0 0 0.6176377252247958 P41896 50.949461750408936 45.0 0.0 no 4395 chrVII_505081r 13660 essential YGR005C 756 + ACAACTTTGGATGAAACCGT T|253|R T|253|I T|254|S T|254|I TFG2 Transcription Factor G 400.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.01814779837348281 P41896 0.9476869702339172 0.9472420215606691 0.9491789937019348 0.9472420215606691 0.009497576393187046 0.047956693917512894 0.22341512143611908 0.3008696436882019 42.31204886166961 40.0 0.0 no 4396 chrVII_505203 13663 essential YGR005C 637 - GCAAACTGTACCCACAATGG C|219|S C|219|Y V|218|L V|218|I TFG2 Transcription Factor G 400.0 0 0 0 0 -0.3745631065857078 P41896 0.9421560168266296 0.9290120005607604 0.9539830088615416 0.9574310183525084 0.041732478886842735 0.015629369765520096 0.07591606676578523 0.4117460250854492 47.1905526351764 50.0 0.0 no 4397 chrVII_505213r 13664 essential YGR005C 624 + CCCAAAAAAACCGCCATTGT silent|CCC>CCG|P|209 silent|CCC>CCT|P|209 P|209|R P|209|L TFG2 Transcription Factor G 400.0 0 0 0 0 0.6962235473691591 P41896 0.9432820081710817 0.9430609941482544 0.0 0.0 45.87573568894976 45.0 0.0 no 4398 chrVII_505355 13666 essential YGR005C 485 - CTTCACGTTCTTGCTTCTTC E|168|Q E|168|K R|167|P R|167|H TFG2 Transcription Factor G 400.0 0 0 0 0 0.05870906915979224 P41896 0.956179976463318 0.9475290179252625 0.9099509716033936 0.9570810198783876 0.3516236245632172 0.5684723258018494 0.2807047665119171 0.14603137969970706 51.40632662148886 45.0 0.0 no 4399 chrVII_505571 13669 essential YGR005C 269 - TCCTAATTTTACCCAGTTCT R|96|T R|96|K R|96|S silent|AGG>AGA|R|96 TFG2 Transcription Factor G 400.0 0 0 0 0 -1.4875594578704985 P41896 0.932735025882721 0.955805003643036 0.9087679982185364 0.02330673672258854 0.5994709134101868 0.018543791025877 49.135002111291676 35.0 0.0 no 4400 chrVII_505671 13674 essential YGR005C 169 - ACGTTCCAAGTCCAAATCTA R|63|P R|63|H E|62|Q E|62|K TFG2 Transcription Factor G 400.0 0 0 0 0 0.7671789594817964 P41896 0.9099509716033936 0.9570810198783876 0.956179976463318 0.9475290179252625 0.2492227852344513 0.12744595110416412 0.3656695783138275 0.5151628255844116 46.14677722587975 40.0 0.0 no 4401 chrVII_505755 13675 essential YGR005C 85 - TTGCGAAAGATACTCATCAC silent|TCG>TCC|S|34 silent|TCG>TCA|S|34 TFG2 Transcription Factor G 400.0 0 0 0 0 -1.1380125180491765 P41896 40.73092924518164 40.0 0.0 no 4402 chrVII_509730 13678 essential YGR009C 1253 - CTTCATCTTCTTCCTGCTGC E|424|Q E|424|K D|423|H D|423|N SEC9 SECretory 651.0 0 0 0 0 1.1473250005835107 P40357 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.12408285588026048 0.022145148366689682 0.0072339470498263845 0.01903469860553741 56.411565944202145 50.0 0.0 no 4403 chrVII_509887 13681 essential YGR009C 1096 - TCTTGAACTATGATCAACTT R|372|T R|372|K SEC9 SECretory 651.0 0 0 0 0 0.07752790715308219 P40357 0.932735025882721 0.955805003643036 0.5165314674377441 0.7488712072372437 38.26855105345624 30.0 0.0 no 4404 chrVII_510179r 13686 essential YGR009C 801 + GCGAACGACTCATATAGTAA A|268|G A|268|V N|269|K silent|AAC>AAT|N|269 SEC9 SECretory 651.0 0 1 0 0 1.2415073047642584 P40357 0.9484469890594482 0.9504740238189696 0.9439849853515624 0.6160593628883362 0.2346771359443665 0.8977937102317809 40.93004073335101 40.0 0.0 no 4405 chrVII_510247 13689 essential YGR009C 736 - ACCGCTAGATCTATTAGTAT G|252|R G|252|S G|252|A G|252|D SEC9 SECretory 651.0 0 0 0 0 -0.7163728733270062 P40357 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.38268613815307617 0.7153881788253784 1.0 0.3003752529621124 44.91980355952404 35.0 0.0 no 4406 chrVII_510320 13694 essential YGR009C 663 - TCTTGCATCGGGTTTGCTAA E|228|Q E|228|K M|226|I M|226|I SEC9 SECretory 651.0 0 1 0 0 0.6125769681702282 P40357 0.956179976463318 0.9475290179252625 0.9553959965705872 0.9553959965705872 0.5901951789855957 0.9113819003105164 0.4191734790802002 0.4191734790802002 50.73765568880458 45.0 0.0 no 4407 chrVII_510557r 13704 essential YGR009C 423 + AGCGTCAATGCTGCGCCTTA S|142|R silent|AGC>AGT|S|142 silent|GTC>GTG|V|143 silent|GTC>GTT|V|143 SEC9 SECretory 651.0 0 0 0 0 0.2027967059193168 P40357 0.9417110085487366 0.6187855005264282 56.247870559025785 55.00000000000001 0.0 no 4408 chrVII_510641 13705 essential YGR009C 342 - TCATCATTTTCGATAGCGTA D|121|H D|121|N D|120|H D|120|N SEC9 SECretory 651.0 0 0 0 0 0.5558743757797153 P40357 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.15842542052268982 0.7127856612205505 0.12999431788921356 0.8420501947402954 44.37610324144953 35.0 0.0 no 4409 chrVII_510742 13711 essential YGR009C 241 - CTCGTTAGCATTGGCATCTA E|87|Q E|87|K SEC9 SECretory 651.0 0 0 0 0 -2.205840516585804 P40357 0.956179976463318 0.9475290179252625 0.4988515675067902 0.9336071014404296 50.567484536566155 45.0 0.0 yes 4410 chrVII_510743 13712 essential YGR009C 240 - TCGTTAGCATTGGCATCTAA E|87|Q E|87|K SEC9 SECretory 651.0 0 0 0 0 0.2290176238235013 P40357 0.956179976463318 0.9475290179252625 0.4988515675067902 0.9336071014404296 47.05286124410993 40.0 0.0 no 4411 chrVII_510927r 13714 essential YGR009C 53 + ACAGAACAAGGATACTTTGA Q|19|E Q|19|* N|20|K silent|AAC>AAT|N|20 SEC9 SECretory 651.0 0 0 0 0 -0.2830431015623585 P40357 0.9590039849281312 0.9439849853515624 0.31780123710632324 0.0 38.30399585141447 35.0 0.0 no 4412 chrVII_514893 13723 essential YGR013W 339 + ATTCATACAGTATCTTTACA H|115|D H|115|Y SNU71 Small NUclear ribonucleoprotein associated 620.0 0 0 0 0 0.5460994666103517 P53207 0.9473130106925964 0.9489949941635132 0.05216217413544655 0.1234961673617363 39.22949946552848 25.0 1.0 no 4413 chrVII_515002r 13724 essential YGR013W 451 - CCAAGCTTCTACTTTCAATG W|157|S W|157|* A|156|P A|156|T SNU71 Small NUclear ribonucleoprotein associated 620.0 0 0 0 0 0.1059239317672982 P53207 0.8858469724655151 0.9573720097541808 0.9523990154266356 0.0 0.1111871302127838 0.15528620779514313 44.45780571499626 40.0 1.0 no 4414 chrVII_515033 13725 essential YGR013W 479 + TTCTTCGTTTTTAGATACCC S|161|C S|161|F S|162|W S|162|L SNU71 Small NUclear ribonucleoprotein associated 620.0 0 0 0 0 -2.224504938137558 P53207 0.945252001285553 0.9294660091400146 0.9288619756698608 0.9298099875450134 0.07269597798585893 0.11330286413431168 0.056212417781353 0.26213330030441284 46.663239322419656 35.0 1.0 yes 4415 chrVII_515327 13729 essential YGR013W 773 + CTCTTCCACACAATACAAAG S|259|C S|259|F S|260|C S|260|F SNU71 Small NUclear ribonucleoprotein associated 620.0 0 0 0 0 0.7178608649841844 P53207 0.945252001285553 0.9294660091400146 0.945252001285553 0.9294660091400146 0.051887165755033486 0.057060167193412774 0.03099378198385238 0.030140800401568413 40.72801049576964 40.0 1.0 no 4416 chrVII_515357 13731 essential YGR013W 803 + CACTTTAAGTGATTTGCCAT T|269|S T|269|I SNU71 Small NUclear ribonucleoprotein associated 620.0 0 0 0 0 0.032069529176511964 P53207 0.9491789937019348 0.9472420215606691 0.0 0.0 44.35684507294997 35.0 1.0 no 4417 chrVII_515539r 13733 essential YGR013W 988 - CTCTGTATTGGCGCTCCCTT E|336|Q E|336|K SNU71 Small NUclear ribonucleoprotein associated 620.0 0 0 0 0 -0.07205467212980765 P53207 0.956179976463318 0.9475290179252625 0.2095802277326584 0.03994004428386688 59.65294045659977 55.00000000000001 1.0 no 4418 chrVII_515722r 13735 essential YGR013W 1171 - ACTCATGATATCAGCCCTAA M|396|I M|396|I S|397|T S|397|N SNU71 Small NUclear ribonucleoprotein associated 620.0 0 0 0 0 0.6876207159796592 P53207 0.9553959965705872 0.9553959965705872 0.9512869715690612 0.9536849856376648 0.40446218848228455 0.40446218848228455 0.5001415610313416 0.4129386842250824 47.81328934906793 40.0 1.0 no 4419 chrVII_515882 13738 essential YGR013W 1328 + AGCTAAAAATGGAAATGCAA A|444|G A|444|V SNU71 Small NUclear ribonucleoprotein associated 620.0 0 0 0 0 -0.574862199314515 P53207 0.9484469890594482 0.9504740238189696 0.2540266811847687 0.18854263424873352 33.83691395890645 30.0 1.0 no 4420 chrVII_515906 13739 essential YGR013W 1352 + ACTGGCGCCTATACAACTAT L|452|V silent|CTG>TTG|L|452 A|453|G A|453|V SNU71 Small NUclear ribonucleoprotein associated 620.0 0 0 0 0 0.26751862912396185 P53207 0.9512209892272948 0.9484469890594482 0.9504740238189696 1.0 0.4952127635478973 0.4207089245319367 48.65868446052025 45.0 1.0 no 4421 chrVII_515910 13740 essential YGR013W 1356 + GCGCCTATACAACTATCGGA P|454|A P|454|S A|453|G A|453|V SNU71 Small NUclear ribonucleoprotein associated 620.0 0 0 0 0 -1.073318239826836 P53207 0.9562489986419678 0.9498909711837769 0.9484469890594482 0.9504740238189696 0.8609097599983215 0.6125080585479736 0.4952127635478973 0.4207089245319367 49.637807200625154 50.0 1.0 no 4422 chrVII_515913r 13741 essential YGR013W 1362 - TTACCATCCGATAGTTGTAT G|460|A G|460|D G|460|R G|460|S SNU71 Small NUclear ribonucleoprotein associated 620.0 0 0 0 0 -1.0694804915300993 P53207 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.7504091262817383 0.6242700219154358 0.5238499045372009 0.7346621751785278 46.037447499094704 35.0 1.0 no 4423 chrVII_527212 13746 high_effect YGR020C 98 - AAACAAAAAAGTTCTTTTCT V|39|L V|39|I VMA7 Vacuolar Membrane Atpase 118.0 0 0 0 0 0.2226279333362924 P39111 0.9539830088615416 0.9574310183525084 0.8747674226760864 0.8443213701248169 0.5537019968032837 -0.6458460092544556 0.10234999656677246 -0.5697900056838989 30.92325894667141 20.0 0.0 no 4424 chrVII_532102r 13751 essential YGR024C 472 + ATCTTTATAATACGACGTTT L|159|V L|159|F THG1 tRNAHis Guanylyltransferase 237.0 0 0 0 0 -0.3559014899046121 P53215 0.02858096733689308 0.027111683040857315 2.6872000694274902 1.2625999450683594 37.352987592286354 25.0 0.0 no 4425 chrVII_532258r 13754 essential YGR024C 316 + CGTCCAATTACGTCGCATTA S|107|C S|107|F silent|TCC>TCG|S|107 silent|TCC>TCT|S|107 THG1 tRNAHis Guanylyltransferase 237.0 0 0 0 0 0.17847493370218093 P53215 0.009173232130706309 0.031752053648233414 48.06378634012748 45.0 0.0 no 4426 chrVII_532318r 13756 essential YGR024C 256 + GTACAACTTTATTTAACAGA T|87|R T|87|I T|88|S T|88|I THG1 tRNAHis Guanylyltransferase 237.0 0 0 0 0 0.7860339179149765 P53215 0.020571548491716385 0.02212599106132984 0.66659015417099 0.14579442143440247 35.25660484247283 25.0 0.0 no 4427 chrVII_532442 13758 essential YGR024C 135 - TTCAAAGCATTTTCATCGTT L|51|F silent|TTG>TTA|L|51 THG1 tRNAHis Guanylyltransferase 237.0 0 0 0 0 -0.2145333444582677 P53215 0.004727409686893225 41.85688115686952 30.0 0.0 no 4428 chrVII_546086r 13766 essential YGR030C 49 + CTTCCTCCACTCAATGTCTT S|18|C S|18|F silent|TCC>TCG|S|18 silent|TCC>TCT|S|18 POP6 Processing Of Precursor RNAs 158.0 0 0 0 0 -0.27876429273701264 P53218 0.03900359943509102 0.024832054972648617 0.8410000205039978 0.378600001335144 52.95589070368038 45.0 0.0 no 4429 chrVII_584939r 13767 essential YGR046W 47 - ACATGCTTACGTTCGTTGAA M|22|I M|22|I S|21|T S|21|N TAM41 Translocator Assembly and Maintenance 385.0 0 0 0 0 -0.1575760426799885 P53230 0.9553959965705872 0.9553959965705872 0.9512869715690612 0.9536849856376648 45.26924143042004 40.0 1.0 no 4430 chrVII_585095r 13774 essential YGR046W 203 - TTCTTATACCTTTTTCCAAG R|74|T R|74|K TAM41 Translocator Assembly and Maintenance 385.0 0 0 0 0 0.8953220600995149 P53230 0.932735025882721 0.955805003643036 0.30137041211128235 0.7152055501937866 43.27029892976452 30.0 1.0 no 4431 chrVII_585165 13775 essential YGR046W 270 + CACAGATTGCCCCCCAACTA H|91|Q silent|CAC>CAT|H|91 TAM41 Translocator Assembly and Maintenance 385.0 0 0 0 0 -0.20798748942199907 P53230 0.9588389992713928 0.5956101417541504 56.86855923013115 55.00000000000001 1.0 no 4432 chrVII_585194 13779 essential YGR046W 299 + CCAGCTCATTACTATCGATA Q|101|E Q|101|* L|102|V L|102|F TAM41 Translocator Assembly and Maintenance 385.0 0 0 0 0 0.5817224338399013 P53230 0.9590039849281312 0.9512209892272948 0.9587849974632264 0.0 0.5042042732238771 0.7027063369750977 46.466744656971635 40.0 1.0 no 4433 chrVII_585261r 13787 essential YGR046W 369 - TAACCAAATACAAACCGGCA G|129|A G|129|D G|129|R G|129|S TAM41 Translocator Assembly and Maintenance 385.0 0 0 0 0 -0.9989803982556688 P53230 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 1.0 0.007740284781903027 0.00636327313259244 0.04465462639927864 41.41229797901218 40.0 1.0 no 4434 chrVII_585288 13789 essential YGR046W 393 + TCAGGAGTTTTCGAACAAGC S|132|* S|132|L TAM41 Translocator Assembly and Maintenance 385.0 0 0 0 0 1.2774636374707529 P53230 0.9298099875450134 0.0 44.413332883019045 45.0 1.0 no 4435 chrVII_585332 13790 essential YGR046W 437 + ACCTCAAATCGATATAATCT P|147|R P|147|L P|147|A P|147|S TAM41 Translocator Assembly and Maintenance 385.0 0 0 0 0 0.8103301696459261 P53230 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.08378104120492935 0.010435270145535469 0.03350907936692238 0.03837209939956665 38.667521603495175 30.0 1.0 no 4436 chrVII_585333r 13792 essential YGR046W 441 - CCCAAGATTATATCGATTTG L|153|F silent|TTG>TTA|L|153 G|154|R G|154|S TAM41 Translocator Assembly and Maintenance 385.0 0 0 0 0 -0.16861075167982806 P53230 0.9587849974632264 0.941340982913971 0.951104998588562 1.0 0.01242412906140089 0.08945807814598082 41.315027410394976 35.0 1.0 no 4437 chrVII_585486r 13793 essential YGR046W 594 - TGTCCATTTATATTTGCAAA G|204|A G|204|E G|204|R G|204|R TAM41 Translocator Assembly and Maintenance 385.0 0 0 0 0 0.333614851202561 P53230 0.9499930143356324 0.9438679814338684 0.941340982913971 0.941340982913971 0.022902116179466248 0.01764262467622757 0.007681366987526417 0.007681366987526417 39.86077651101357 25.0 1.0 no 4438 chrVII_587277 13801 essential YGR047C 2173 - CGACAATCCTCTCAATTCTG L|730|F silent|TTG>TTA|L|730 TFC4 Transcription Factor class C 1025.0 0 0 0 0 -0.035976444286505815 P33339 0.8682780265808105 0.05126165226101875 45.14811877816311 45.0 0.0 no 4439 chrVII_587373r 13803 essential YGR047C 2074 + AGCTTGATTTCCAAATTGAA L|693|V L|693|F TFC4 Transcription Factor class C 1025.0 0 0 0 0 0.2477540735612621 P33339 1.0212199687957764 0.90972101688385 0.4247654676437378 0.02767270803451538 40.03307335725748 30.0 0.0 no 4440 chrVII_587511r 13806 essential YGR047C 1936 + AAGCCAAACAGGCATCTATA A|647|G A|647|V silent|GCC>GCG|A|647 silent|GCC>GCT|A|647 TFC4 Transcription Factor class C 1025.0 0 0 0 0 0.18137311125624733 P33339 1.0252000093460083 1.01350998878479 0.3863988816738129 0.29174959659576416 44.41103206301915 40.0 0.0 no 4441 chrVII_587929 13808 essential YGR047C 1521 - TCCTTGTAGCATCTTGCTAG K|513|N silent|AAG>AAA|K|513 E|514|Q E|514|K TFC4 Transcription Factor class C 1025.0 0 0 0 0 -0.38519616608586416 P33339 0.9393060207366944 0.8158079981803894 0.8881549835205078 0.21604304015636444 0.10627658665180206 0.11192888766527176 51.687545985318366 45.0 0.0 no 4442 chrVII_587978r 13809 essential YGR047C 1469 + TACGCCGTTGTTATCCCTTG T|491|R T|491|M P|492|A P|492|S TFC4 Transcription Factor class C 1025.0 0 0 0 0 -0.5332982428615597 P33339 0.9680010080337524 0.8711709976196289 0.9928119778633118 0.9389230012893676 0.4095124900341034 0.23340414464473724 0.10991062968969344 0.07913769036531447 54.24798333502129 50.0 0.0 no 4443 chrVII_588157 13811 essential YGR047C 1293 - AATCTAACTCTAATATCGAT R|437|T R|437|K TFC4 Transcription Factor class C 1025.0 0 0 0 0 0.7675135561553813 P33339 0.915220022201538 1.01010000705719 0.04255666583776474 0.5571136474609375 34.8398936393212 25.0 0.0 no 4444 chrVII_588077 13812 essential YGR047C 1373 - CACTGAAAGTCTCATCATAC S|464|T S|464|N TFC4 Transcription Factor class C 1025.0 0 0 0 0 -1.089436903100884 P33339 1.0164999961853027 0.9763870239257812 0.5139826536178589 0.4214607775211334 40.779709109134274 40.0 0.0 no 4445 chrVII_588269 13814 essential YGR047C 1181 - GAACATGATCCCAAAATGTC V|400|L V|400|I TFC4 Transcription Factor class C 1025.0 0 0 0 0 -0.6796939076419404 P33339 1.009119987487793 1.0202499628067017 0.3877710998058319 0.4927971363067627 41.11771868545185 40.0 0.0 no 4446 chrVII_588377r 13821 essential YGR047C 1070 + GTCTTCTTTGAACATTCTCG S|358|C S|358|F S|359|C S|359|F TFC4 Transcription Factor class C 1025.0 0 0 0 0 0.9750434426351312 P33339 0.8315150141716003 0.8087649941444397 0.8504049777984619 0.8803690075874329 0.0 0.0 0.051838260143995285 0.038710035383701324 44.862435966200344 40.0 0.0 no 4447 chrVII_588388 13822 essential YGR047C 1062 - TTCAAAGAAGACCAGTCAAA L|360|F silent|TTG>TTA|L|360 TFC4 Transcription Factor class C 1025.0 0 0 0 0 -0.7661524760474898 P33339 0.8942779898643494 0.0 37.72723494760231 35.0 0.0 no 4448 chrVII_588464 13823 essential YGR047C 986 - GCCTATCTTCATCTTGTTCA R|335|T R|335|K R|335|S silent|AGG>AGA|R|335 TFC4 Transcription Factor class C 1025.0 0 0 0 0 -0.0929638362966067 P33339 0.9989910125732422 1.041210055351257 0.9785590171813964 52.10403562511442 40.0 0.0 no 4449 chrVII_588498 13825 essential YGR047C 952 - GTCTGCATCCTCCCCTTCTG D|324|H D|324|N A|323|P A|323|T TFC4 Transcription Factor class C 1025.0 0 0 0 0 -0.6067580853016523 P33339 0.9012399911880492 1.0283999443054201 1.0233800411224363 1.0362900495529177 64.17417930692369 60.0 0.0 no 4450 chrVII_588511r 13827 essential YGR047C 936 + GACGAAGAAAGCGCCGCAGA D|313|E silent|GAC>GAT|D|313 TFC4 Transcription Factor class C 1025.0 0 1 0 0 0.8549271312268192 P33339 1.0228699445724487 1.0 49.15180717501642 60.0 0.0 no 4451 chrVII_588633r 13830 essential YGR047C 814 + TTCTTTATGTTGATTATGAT L|273|V L|273|F TFC4 Transcription Factor class C 1025.0 0 0 0 0 0.3405196717223853 P33339 1.0041899681091309 0.8773840069770813 0.8848328590393066 0.05733647570014 36.78734037924573 20.0 0.0 no 4452 chrVII_588659r 13831 essential YGR047C 788 + TGCAAACATATTGAGGGAGT A|264|G A|264|V N|265|K silent|AAC>AAT|N|265 TFC4 Transcription Factor class C 1025.0 0 0 0 0 0.4291297420656651 P33339 1.0165300369262695 1.0061800479888916 0.929973006248474 0.37968066334724426 0.2809271812438965 1.0 42.49446663748381 40.0 0.0 no 4453 chrVII_588667 13832 essential YGR047C 783 - CTCAATATGTTTGCATCATA L|267|F silent|TTG>TTA|L|267 TFC4 Transcription Factor class C 1025.0 0 0 0 0 1.2637530780458721 P33339 0.936719000339508 0.07645778357982635 40.93298570388372 30.0 0.0 no 4454 chrVII_588807r 13835 essential YGR047C 640 + AGGCCATCTACTGCTTTTCC A|215|G A|215|V silent|GCC>GCG|A|215 silent|GCC>GCT|A|215 TFC4 Transcription Factor class C 1025.0 0 0 0 0 1.0341963344022254 P33339 0.8447080254554749 0.8868370056152344 0.0 0.0 56.56218802328562 50.0 0.0 no 4455 chrVII_588828 13836 essential YGR047C 622 - CTGCCTAACATGATCTAAAT R|213|S silent|AGG>AGA|R|213 R|213|T R|213|K TFC4 Transcription Factor class C 1025.0 0 0 0 0 0.4373368766555669 P33339 0.9085509777069092 0.930059015750885 0.9859189987182616 0.9542655348777772 0.8451780080795288 0.9869323968887328 40.719940225039686 35.0 0.0 no 4456 chrVII_588867 13839 essential YGR047C 583 - TATCTTCCAGAATTCCCAAT K|200|N silent|AAG>AAA|K|200 W|199|C W|199|* TFC4 Transcription Factor class C 1025.0 0 0 0 0 0.6636543675095051 P33339 0.9462829828262328 0.7381510138511658 0.3102276623249054 0.0 46.260288723016465 35.0 0.0 no 4457 chrVII_588878 13840 essential YGR047C 572 - ATTCCCAATCGGAAGCATTT E|197|Q E|197|K W|196|C W|196|* TFC4 Transcription Factor class C 1025.0 0 1 0 0 -0.17967485776829645 P33339 0.9794340133666992 0.9581050276756288 0.9010379910469056 0.15143272280693054 0.029032580554485318 0.1769734025001526 47.546981561328145 40.0 0.0 no 4458 chrVII_588881r 13841 essential YGR047C 566 + TCACCTAAATGCTTCCGATT H|190|Q silent|CAC>CAT|H|190 H|190|D H|190|Y TFC4 Transcription Factor class C 1025.0 0 1 0 0 -1.4921701419676987 P33339 0.8606600165367126 0.8543540239334106 0.9305359721183776 0.0 0.0 0.0 47.08017769137143 40.0 0.0 no 4459 chrVII_588882r 13842 essential YGR047C 565 + CTCACCTAAATGCTTCCGAT H|190|D H|190|Y H|190|Q silent|CAC>CAT|H|190 TFC4 Transcription Factor class C 1025.0 0 1 0 0 0.11099007109836187 P33339 0.8543540239334106 0.9305359721183776 0.8606600165367126 0.0 0.0 0.0 48.50910557174365 45.0 0.0 no 4460 chrVII_589031r 13845 essential YGR047C 416 + TGTCAGGAATGATTTACAAG silent|GTC>GTG|V|140 silent|GTC>GTT|V|140 TFC4 Transcription Factor class C 1025.0 0 0 0 0 0.5955787490849035 P33339 37.71589278773712 35.0 0.0 no 4461 chrVII_589047r 13846 essential YGR047C 400 + AAGCCAATGAAGCTTTTGTC A|135|G A|135|V silent|GCC>GCG|A|135 silent|GCC>GCT|A|135 TFC4 Transcription Factor class C 1025.0 0 0 0 0 -0.2792652436694715 P33339 0.9370980262756348 0.9374179840087892 0.17233730852603912 0.018616974353790283 44.546424402301064 40.0 0.0 no 4462 chrVII_590100 13858 essential YGR048W 274 + GCAGAGTTTACTTACCACAA silent|GGC>GGG|G|92 silent|GGC>GGT|G|92 UFD1 Ubiquitin Fusion Degradation protein 361.0 0 0 0 0 -0.2328057296839654 P53044 45.83640241453492 40.0 1.0 no 4463 chrVII_590289r 13863 essential YGR048W 466 - AATCTCAATAACATCGTCCA E|161|D silent|GAG>GAA|E|161 E|161|Q E|161|K UFD1 Ubiquitin Fusion Degradation protein 361.0 0 0 0 0 0.2727963915308985 P53044 0.94931298494339 0.956179976463318 0.9475290179252625 0.4986963868141174 0.7094210386276245 0.8051880002021791 1.9032000303268437 -0.3937999904155731 -1.0980000495910645 41.99431180351331 35.0 1.0 no 4464 chrVII_590420r 13866 essential YGR048W 597 - TCCGGTTCCACATATCCTAC silent|CCG>CCC|P|205 silent|CCG>CCA|P|205 D|206|H D|206|N UFD1 Ubiquitin Fusion Degradation protein 361.0 0 0 0 0 -1.4197684120962897 P53044 0.9486550092697144 0.956179976463318 0.1080394685268402 0.4371282458305359 0.032600000500679016 -0.06499999761581421 54.14779106363785 50.0 1.0 no 4465 chrVII_590513r 13871 essential YGR048W 690 - GATCCCTGGCCAAGCACCGA G|236|A G|236|E G|236|R G|236|R UFD1 Ubiquitin Fusion Degradation protein 361.0 0 0 0 0 -0.6539899290122083 P53044 0.9499930143356324 0.9438679814338684 0.941340982913971 0.941340982913971 0.0 0.0 0.0 0.0 60.715885133325116 65.0 1.0 no 4466 chrVII_590582 13874 essential YGR048W 756 + AACAAACTATCTAAATTTGT N|253|K silent|AAC>AAT|N|253 L|255|V silent|CTA>TTA|L|255 UFD1 Ubiquitin Fusion Degradation protein 361.0 0 1 0 0 -0.2974495298164964 P53044 0.9439849853515624 0.9512209892272948 0.938916265964508 0.6554855704307556 31.471175880210982 20.0 1.0 no 4467 chrVII_590620 13876 essential YGR048W 794 + ATCTGGTAAAGCTCCGAAAG S|266|C S|266|F UFD1 Ubiquitin Fusion Degradation protein 361.0 0 1 0 0 -1.2912589481283652 P53044 0.945252001285553 0.9294660091400146 0.04011752083897591 0.036127947270870216 43.26139945106394 45.0 1.0 no 4468 chrVII_610654r 13880 essential YGR060W 93 - TTCTCCATGAAATTCAATTG E|37|D silent|GAG>GAA|E|37 E|37|Q E|37|K ERG25 ERGosterol biosynthesis 309.0 0 0 0 0 -0.4824821848207384 P53045 0.94931298494339 0.956179976463318 0.9475290179252625 0.0 0.0 0.0 38.203281813305246 30.0 1.0 no 4469 chrVII_610927r 13886 essential YGR060W 366 - ATACCTAATTTTTCACACAT G|128|A G|128|D G|128|R G|128|S ERG25 ERGosterol biosynthesis 309.0 0 0 0 0 0.4656032170897838 P53045 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.0087065864354372 0.020481076091527942 0.010460738092660904 0.013343226164579391 39.68245245278786 25.0 1.0 no 4470 chrVII_611092 13890 essential YGR060W 528 + CACAGATACGCTGCTCCATT H|177|Q silent|CAC>CAT|H|177 ERG25 ERGosterol biosynthesis 309.0 0 0 0 0 -1.5102558333363592 P53045 0.9588389992713928 0.0 51.794699178690784 50.0 1.0 no 4471 chrVII_611136 13891 essential YGR060W 572 + TCCTGCTGAAACTTTGTCTT P|192|R P|192|L P|192|A P|192|S ERG25 ERGosterol biosynthesis 309.0 0 0 0 0 0.15303039405580324 P53045 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 47.8934044080242 40.0 1.0 no 4472 chrVII_611137 13892 essential YGR060W 573 + CCTGCTGAAACTTTGTCTTT P|192|R P|192|L A|193|G A|193|V ERG25 ERGosterol biosynthesis 309.0 0 0 0 0 -0.5428667585286233 P53045 0.9432820081710817 0.9430609941482544 0.9484469890594482 0.9504740238189696 0.0 0.0 0.025618366897106167 0.4253402352333069 47.119991176198255 40.0 1.0 no 4473 chrVII_611240r 13895 essential YGR060W 679 - AACAGCTTGGAATAATCTTA V|233|L V|233|I A|232|P A|232|T ERG25 ERGosterol biosynthesis 309.0 0 0 0 0 -0.7690694861555936 P53045 0.9539830088615416 0.9574310183525084 0.9573720097541808 0.9523990154266356 0.02966554835438728 1.0 0.011563651263713837 0.16550973057746887 38.00889329154745 30.0 1.0 no 4474 chrVII_618606 13899 essential YGR065C 1233 - TACGCAAATCCTAAACATGC silent|GCG>GCC|A|417 silent|GCG>GCA|A|417 A|417|P A|417|T 0 0 0 0 -1.03284419442319 P53241 0.9573720097541808 0.9523990154266356 0.02094765566289425 0.06732572615146637 41.17773038070163 40.0 0.0 no 4475 chrVII_618619 13900 essential YGR065C 1220 - AACATGCGGGTATAACACTC C|413|S C|413|Y A|412|P A|412|T 0 0 0 0 -0.4448761418535093 P53241 0.9421560168266296 0.9290120005607604 0.9573720097541808 0.9523990154266356 0.2822985649108887 0.0195467509329319 1.0 0.011593800038099287 44.061575327409 45.0 0.0 no 4476 chrVII_618631 13901 essential YGR065C 1208 - TAACACTCAGGTTGTTCACT V|409|L V|409|I S|408|T S|408|N 0 0 0 0 -0.10047548339255392 P53241 0.9539830088615416 0.9574310183525084 0.9512869715690612 0.9536849856376648 0.2932361662387848 0.5036548376083374 1.0 0.21912617981433868 46.141514604585105 40.0 0.0 no 4477 chrVII_619040 13911 essential YGR065C 799 - TTGCAGAAGTCCTGAAGTCA silent|CTG>CTC|L|272 silent|CTG>CTA|L|272 0 0 0 0 -0.27974750004996696 P53241 48.094684879526206 45.0 0.0 no 4478 chrVII_619096 13914 essential YGR065C 743 - CTCTTGAATTAATTTCATCT R|254|T R|254|K 0 0 0 0 0.7751305416973691 P53241 0.932735025882721 0.955805003643036 0.09145309776067734 0.13462412357330322 37.52673913196333 25.0 0.0 no 4479 chrVII_619097 13916 essential YGR065C 742 - TCTTGAATTAATTTCATCTG R|254|T R|254|K 0 0 0 0 0.6259267739133761 P53241 0.932735025882721 0.955805003643036 0.09145309776067734 0.13462412357330322 35.737361699107794 25.0 0.0 no 4480 chrVII_619124 13917 essential YGR065C 715 - CCAACAACCTAGTATATATT W|245|S W|245|* C|244|S C|244|Y 0 0 0 0 -1.2799076310594426 P53241 0.8858469724655151 0.9421560168266296 0.9290120005607604 0.002724555786699057 1.0 0.0106241749599576 40.10030255880474 30.0 0.0 no 4481 chrVII_619195r 13920 essential YGR065C 641 + AAACTCACTAGCCGAACTAA N|215|K silent|AAC>AAT|N|215 S|216|* S|216|L 0 0 0 0 0.6408794232148364 P53241 0.9439849853515624 0.9298099875450134 1.0 0.02224000915884972 41.48971127941115 40.0 0.0 no 4482 chrVII_619219r 13921 essential YGR065C 617 + GTTCACATTTGCATGTTATA F|207|L silent|TTC>TTT|F|207 T|208|R T|208|I 0 0 0 0 -0.3271016389009757 P53241 0.9387490153312684 0.9476869702339172 0.9472420215606691 1.0 0.0 0.0 43.128902261676906 30.0 0.0 no 4483 chrVII_619258r 13922 essential YGR065C 578 + TCATATTATTTTGCCTGTAA H|194|D H|194|Y 0 0 0 0 -0.19105675969790886 P53241 0.9473130106925964 0.9489949941635132 0.4581523537635803 0.06458275020122528 41.17805463418397 25.0 0.0 no 4484 chrVII_619573r 13927 essential YGR065C 263 + ATTCGAGTATCGTGTTAATA F|89|L silent|TTC>TTT|F|89 0 0 0 0 -0.23265915335201265 P53241 0.9387490153312684 0.06266970187425612 39.825730437373856 30.0 0.0 no 4485 chrVII_619626 13928 essential YGR065C 213 - GCTTCATCTCTCACTTCATA A|78|P A|78|T E|77|Q E|77|K 0 0 0 0 0.4644502339921848 P53241 0.9573720097541808 0.9523990154266356 0.956179976463318 0.9475290179252625 0.03782469406723976 0.24290868639945984 0.02725563384592533 0.022890746593475345 49.91698270022765 40.0 0.0 no 4486 chrVII_639940 13935 high_effect YGR078C 412 - TTTCTTCTTTAACAACTCTA K|143|N silent|AAG>AAA|K|143 K|142|N silent|AAG>AAA|K|142 PAC10 Perish in the Absence of Cin8p 199.0 0 0 0 0 0.2889498545757286 P48363 0.9355990290641784 0.9355990290641784 0.4042341411113739 0.5496373772621155 38.666347160081436 25.0 0.0 no 4487 chrVII_640016 13940 high_effect YGR078C 336 - TTCAAATCCGCCCGATCTTC L|118|F silent|TTG>TTA|L|118 PAC10 Perish in the Absence of Cin8p 199.0 0 0 0 0 -1.1511597970498972 P48363 0.9587849974632264 0.05127045512199402 51.865116412081136 50.0 0.0 no 4488 chrVII_640053r 13941 high_effect YGR078C 296 + GAACGACACGCTCTACACAA N|100|K silent|AAC>AAT|N|100 D|101|E silent|GAC>GAT|D|101 PAC10 Perish in the Absence of Cin8p 199.0 0 0 0 0 0.3749380799708783 P48363 0.9439849853515624 0.9532920122146606 0.023971866816282272 0.07718635350465775 44.91712883577907 50.0 0.0 no 4489 chrVII_640047r 13942 high_effect YGR078C 302 + CACGCTCTACACAAAGGCTC T|102|R T|102|M L|103|V L|103|F PAC10 Perish in the Absence of Cin8p 199.0 0 0 0 0 -1.3949839508813664 P48363 0.9476869702339172 0.9502379894256592 0.9512209892272948 0.9587849974632264 0.0 0.0 0.010242163203656672 0.009041954763233662 49.14713639833696 55.00000000000001 0.0 no 4490 chrVII_640331r 13951 high_effect YGR078C 18 + TCCACGGAAAAGAATGCCAG silent|TCC>TCG|S|7 silent|TCC>TCT|S|7 S|7|C S|7|F PAC10 Perish in the Absence of Cin8p 199.0 0 0 0 0 0.5274568976811226 P48363 0.945252001285553 0.9294660091400146 0.0549059584736824 0.052910279482603066 44.679572339721176 50.0 0.0 no 4491 chrVII_644152r 13956 essential YGR082W 111 - CTCAACACTTTCCTGAATTG L|43|F silent|TTG>TTA|L|43 silent|GTG>GTC|V|42 silent|GTG>GTA|V|42 TOM20 Translocase of the Outer Mitochondrial membrane 183.0 0 0 0 0 0.2387891053943759 P35180 0.026542935520410538 43.00556861748753 40.0 1.0 no 4492 chrVII_644327r 13964 essential YGR082W 286 - TCTTTCACCATTTTCTACGT R|102|T R|102|K E|101|Q E|101|K TOM20 Translocase of the Outer Mitochondrial membrane 183.0 0 0 0 0 1.1636786797468583 P35180 0.3716164231300354 1.0 0.0 0.0 47.7575392794077 35.0 1.0 no 4493 chrVII_645373r 13971 essential YGR083C 1420 + CCCATTCTATCCTATCTAAT H|475|D H|475|Y silent|GCC>GCG|A|474 silent|GCC>GCT|A|474 GCD2 General Control Derepressed 651.0 0 0 0 0 -0.5775227511906927 P12754 0.055462654680013664 0.008804589509963991 47.4783752906181 35.0 0.0 no 4494 chrVII_645605r 13975 essential YGR083C 1188 + TCTACTACTATTGTGACATA S|397|C S|397|F T|398|S T|398|I GCD2 General Control Derepressed 651.0 0 0 0 0 1.0141791243099736 P12754 0.0037534914445132017 0.003123743925243616 0.6825441718101501 0.04019730538129807 39.89761150650372 30.0 0.0 no 4495 chrVII_645791 13978 essential YGR083C 1005 - TTACCCATAGTAACACTTAA G|341|A G|341|D G|341|R G|341|S GCD2 General Control Derepressed 651.0 0 0 0 0 -0.3512078287947724 P12754 0.0 0.0 0.0 0.0 40.7486083803866 30.0 0.0 no 4496 chrVII_645794r 13979 essential YGR083C 999 + AGACCTTTAAGTGTTACTAT P|335|A P|335|S P|335|R P|335|L GCD2 General Control Derepressed 651.0 0 0 0 0 -0.4998938448593664 P12754 0.0 0.0 0.0 0.0 41.46975155582317 30.0 0.0 no 4497 chrVII_646184 13988 essential YGR083C 612 - ATCTCTTGTTGTATAGCTGT E|210|D silent|GAG>GAA|E|210 E|210|Q E|210|K GCD2 General Control Derepressed 651.0 0 0 0 0 0.2515217358280083 P12754 0.5908176302909851 0.5800189971923828 0.952723264694214 47.69393042391538 35.0 0.0 no 4498 chrVII_646341r 13994 essential YGR083C 452 + ATCAGGATCTAACGTATTAA S|152|* S|152|L GCD2 General Control Derepressed 651.0 0 0 0 0 -1.8032961076377487 P12754 0.11952748149633408 37.924322526488474 30.0 0.0 no 4499 chrVII_646386r 13996 essential YGR083C 407 + AATCACCGCTGCTGGGTTGA I|137|M silent|ATC>ATT|I|137 T|138|S T|138|I GCD2 General Control Derepressed 651.0 0 0 0 0 0.419020345346168 P12754 0.29601410031318665 0.2586109936237335 0.07015388458967209 54.86531763505229 55.00000000000001 0.0 no 4500 chrVII_662417 14005 essential YGR090W 59 + GCAAAAGAAACATTCCACAC Q|21|E Q|21|* UTP22 U Three Protein 1237.0 0 0 0 0 -0.028025615057245074 P53254 0.9590039849281312 1.0 38.92154242724155 40.0 1.0 no 4501 chrVII_662461r 14006 essential YGR090W 106 - ACTACTGTGATCATTTTCTT S|42|T S|42|N S|41|T S|41|N UTP22 U Three Protein 1237.0 1 Series([], Name: modification, dtype: object) 0 0 0 1.018243499345086 P53254 0.9512869715690612 0.9536849856376648 0.9512869715690612 0.9536849856376648 0.502354621887207 0.4404613077640533 0.8585898876190186 0.2693230509757996 42.95696261287464 30.0 1.0 no 4502 chrVII_662488r 14007 essential YGR090W 133 - GGGCACGGTACGCTCGTTGA silent|GTG>GTC|V|50 silent|GTG>GTA|V|50 V|50|L V|50|M UTP22 U Three Protein 1237.0 0 0 0 0 -1.4175510982191126 P53254 0.9539830088615416 0.9587630033493042 0.3014616072177887 0.10570036619901656 57.7432431579033 65.0 1.0 no 4503 chrVII_662534 14009 essential YGR090W 176 + TACTTCACCTGAAAGTAACG T|60|S T|60|I S|61|* S|61|L UTP22 U Three Protein 1237.0 1 Series([], Name: modification, dtype: object) 0 0 0 -1.157298178723138 P53254 0.9491789937019348 0.9472420215606691 0.9298099875450134 0.7590512037277222 0.2272992879152298 0.24719448387622836 40.32073017359436 40.0 1.0 no 4504 chrVII_662916 14017 essential YGR090W 558 + GGCTCCTTTGCTCTTAAAGC silent|GGC>GGG|G|187 silent|GGC>GGT|G|187 S|188|C S|188|F UTP22 U Three Protein 1237.0 0 0 0 0 -1.0803936638983358 P53254 0.945252001285553 0.9294660091400146 0.018980057910084724 0.009088647551834585 53.12238851270792 50.0 1.0 no 4505 chrVII_662969 14019 essential YGR090W 611 + TACTTTACTAACAATGCCAA T|205|S T|205|I UTP22 U Three Protein 1237.0 0 0 0 0 0.27205289277515804 P53254 0.9491789937019348 0.9472420215606691 0.013717273250222206 0.4887174069881439 39.07522317482852 30.0 1.0 no 4506 chrVII_663065r 14020 essential YGR090W 710 - TCAATAATATCAATAGGTGG L|243|F silent|TTG>TTA|L|243 UTP22 U Three Protein 1237.0 0 0 0 0 -0.8942929528318476 P53254 0.9587849974632264 0.2765766978263855 35.22991399263128 30.0 1.0 no 4507 chrVII_663225 14022 essential YGR090W 867 + TTCTCTATCAACTTGCTTAT F|290|L silent|TTC>TTT|F|290 S|291|C S|291|F UTP22 U Three Protein 1237.0 0 0 0 0 0.3653492188667967 P53254 0.9387490153312684 0.945252001285553 0.9294660091400146 0.3040894567966461 0.054227396845817566 0.09060892462730408 42.929433048361204 30.0 1.0 no 4508 chrVII_663220r 14023 essential YGR090W 865 - AAGCAAGTTGATAGAGAATC L|294|F silent|TTG>TTA|L|294 UTP22 U Three Protein 1237.0 0 0 0 0 -0.7478876743456225 P53254 0.9587849974632264 0.061798684298992164 36.68967351581472 35.0 1.0 no 4509 chrVII_663483 14026 essential YGR090W 1125 + TCATCCAATATGTCGCATTC S|376|* S|376|L S|377|C S|377|F UTP22 U Three Protein 1237.0 0 0 0 0 0.7463446565490045 P53254 0.9298099875450134 0.945252001285553 0.9294660091400146 0.11848683655261992 0.0 0.0 46.503201155949114 40.0 1.0 no 4510 chrVII_663606 14030 essential YGR090W 1248 + TCATCATACCAATTGTTTAA S|417|* S|417|L S|418|* S|418|L UTP22 U Three Protein 1237.0 0 0 0 0 -0.4338465204948627 P53254 0.9298099875450134 0.9298099875450134 0.0 0.0 38.71226702642372 25.0 1.0 no 4511 chrVII_663714r 14032 essential YGR090W 1359 - TCATCAATATATTTAGAAGC E|460|Q E|460|K D|459|H D|459|N UTP22 U Three Protein 1237.0 0 0 0 0 0.2148226218109333 P53254 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.4024847447872162 0.455109179019928 0.129681333899498 0.4934922158718109 34.554672152033675 25.0 1.0 no 4512 chrVII_663717 14033 essential YGR090W 1359 + GCTTCTAAATATATTGATGA A|454|G A|454|V S|455|C S|455|F UTP22 U Three Protein 1237.0 0 0 0 0 0.7794557907057522 P53254 0.9484469890594482 0.9504740238189696 0.945252001285553 0.9294660091400146 0.5199322104454039 0.3901954889297485 0.1129669025540352 0.14509843289852142 35.874996041073416 25.0 1.0 no 4513 chrVII_663936 14037 essential YGR090W 1578 + TACGATGTACAGTTACCTTT Y|527|* silent|TAC>TAT|Y|527 UTP22 U Three Protein 1237.0 0 0 0 0 -0.731125560873527 P53254 44.20765723424023 35.0 1.0 no 4514 chrVII_663978 14038 essential YGR090W 1620 + ACTTCTTTAGCTGCTACATT T|541|S T|541|I S|542|C S|542|F UTP22 U Three Protein 1237.0 0 0 0 0 1.2570367990192732 P53254 0.9491789937019348 0.9472420215606691 0.945252001285553 0.9294660091400146 47.13976021158652 35.0 1.0 no 4515 chrVII_663979 14039 essential YGR090W 1621 + CTTCTTTAGCTGCTACATTT S|542|C S|542|F UTP22 U Three Protein 1237.0 0 0 0 0 -0.946416307721916 P53254 0.945252001285553 0.9294660091400146 46.938869576805814 35.0 1.0 no 4516 chrVII_664219r 14042 essential YGR090W 1864 - GACTAATTTGTCACATTCAG V|628|L V|628|I UTP22 U Three Protein 1237.0 0 0 0 0 0.11175762008338523 P53254 0.9539830088615416 0.9574310183525084 0.04378858208656311 0.2034977823495865 40.20736382768854 35.0 1.0 no 4517 chrVII_664218r 14043 essential YGR090W 1863 - ACTAATTTGTCACATTCAGA V|628|L V|628|I UTP22 U Three Protein 1237.0 0 0 0 0 0.06445607007531345 P53254 0.9539830088615416 0.9574310183525084 0.04378858208656311 0.2034977823495865 40.20736382768854 30.0 1.0 no 4518 chrVII_664313 14047 essential YGR090W 1955 + ATCTTCCTTAAGAAGATTCA S|653|C S|653|F S|654|C S|654|F UTP22 U Three Protein 1237.0 0 0 0 0 -0.10061164879749146 P53254 0.945252001285553 0.9294660091400146 0.945252001285553 0.9294660091400146 0.018930738791823387 0.009800017811357977 0.01860668510198593 0.02633887343108654 40.65046804995171 30.0 1.0 no 4519 chrVII_664318r 14050 essential YGR090W 1963 - GCCATCCTTGAATCTTCTTA G|661|R G|661|S G|661|A G|661|D UTP22 U Three Protein 1237.0 0 0 0 0 0.12999942367965192 P53254 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 50.24787619635322 40.0 1.0 no 4520 chrVII_664342 14051 essential YGR090W 1984 + CCATCACCCATTGTTGTGTT silent|TCC>TCG|S|662 silent|TCC>TCT|S|662 I|663|M silent|ATC>ATT|I|663 UTP22 U Three Protein 1237.0 0 0 0 0 1.2681024573796795 P53254 0.9598389863967896 0.008871125988662243 54.51159972464996 45.0 1.0 no 4521 chrVII_664688 14059 essential YGR090W 2330 + TTTCTTTCAAGACGTCATTT F|778|L silent|TTC>TTT|F|778 UTP22 U Three Protein 1237.0 0 0 0 0 0.4577282431694242 P53254 0.9387490153312684 0.18624702095985413 42.075365145700225 30.0 1.0 no 4522 chrVII_664881 14063 essential YGR090W 2523 + ATCTTGACACCTGAAGGTTA I|842|M silent|ATC>ATT|I|842 UTP22 U Three Protein 1237.0 0 0 0 0 0.8047963360246669 P53254 0.9598389863967896 0.012838616035878658 45.73924216933268 40.0 1.0 no 4523 chrVII_666740r 14069 essential YGR091W 402 - ATCACTTTTGAGTATTGTAA silent|GTG>GTC|V|140 silent|GTG>GTA|V|140 V|140|L V|140|M PRP31 Pre-mRNA Processing 494.0 0 0 0 0 0.7622085569869836 P49704 0.9539830088615416 0.9587630033493042 0.048027627170085914 0.011339237913489342 38.214388449371775 25.0 1.0 no 4524 chrVII_666996r 14073 essential YGR091W 658 - GGCAATTATTGATATCTTTG A|226|P A|226|T PRP31 Pre-mRNA Processing 494.0 0 0 0 0 -0.9240264321903244 P49704 0.9573720097541808 0.9523990154266356 0.0 0.0 38.977891823864006 30.0 1.0 no 4525 chrVII_667423r 14084 essential YGR091W 1085 - CAGCTCTTTTCTTTTTGGGT A|368|P A|368|T R|367|T R|367|K PRP31 Pre-mRNA Processing 494.0 0 0 0 0 0.6348499369291786 P49704 0.9573720097541808 0.9523990154266356 0.932735025882721 0.955805003643036 0.02650178782641888 0.02994744293391705 0.0 0.0 51.44611365465329 40.0 1.0 no 4526 chrVII_672229 14085 essential YGR094W 43 + GGCTTTTGAACTGTCATTAT L|16|V L|16|F VAS1 VAlyl-tRNA Synthetase 1104.0 0 0 0 0 -0.1630085583676956 P07806 0.9512209892272948 0.9587849974632264 44.32980269868153 35.0 1.0 no 4527 chrVII_672371 14089 essential YGR094W 185 + GGTCATCATTAATCCGTTAA silent|GTC>GTG|V|63 silent|GTC>GTT|V|63 I|64|M silent|ATC>ATT|I|64 VAS1 VAlyl-tRNA Synthetase 1104.0 0 0 0 0 -0.0625229816838826 P07806 0.9598389863967896 0.1332750767469406 43.69979113815151 35.0 1.0 no 4528 chrVII_672405r 14091 essential YGR094W 222 - TCAATTTCCTTAGGAGTCTT E|81|Q E|81|K VAS1 VAlyl-tRNA Synthetase 1104.0 0 0 0 0 -1.8738031345425001 P07806 0.956179976463318 0.9475290179252625 0.10285617411136627 0.8846361637115479 46.29423137275177 35.0 1.0 no 4529 chrVII_672634 14093 essential YGR094W 448 + CTGCTAACGTTGAAAGTTCT A|151|G A|151|V VAS1 VAlyl-tRNA Synthetase 1104.0 0 0 0 0 -0.6883779234743765 P07806 0.9484469890594482 0.9504740238189696 0.3896133899688721 0.28849512338638306 42.76665233294955 40.0 1.0 no 4530 chrVII_672759 14097 essential YGR094W 573 + GTCACTGGTGCCTTACATAT silent|GTC>GTG|V|192 silent|GTC>GTT|V|192 T|193|S T|193|I VAS1 VAlyl-tRNA Synthetase 1104.0 0 0 0 0 -0.1680380020754358 P07806 0.9491789937019348 0.9472420215606691 0.0 0.0 51.7544057687764 45.0 1.0 no 4531 chrVII_672855 14098 essential YGR094W 669 + TTGCCAGGTTTCGACCATGC P|225|A P|225|S P|225|R P|225|L VAS1 VAlyl-tRNA Synthetase 1104.0 0 0 0 0 -0.3473334293187389 P07806 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.0 0.0 0.0 0.0 56.254253424858796 55.00000000000001 1.0 no 4532 chrVII_672892r 14101 essential YGR094W 709 - CCAGATTTGCTTCTCCACAA W|243|S W|243|* VAS1 VAlyl-tRNA Synthetase 1104.0 0 0 0 0 -0.15726319779660902 P07806 0.8858469724655151 0.14190611243247986 50.9676797802681 45.0 1.0 no 4533 chrVII_673068r 14105 essential YGR094W 885 - TCAACAGACTTGGTCAATTC E|302|Q E|302|K V|301|L V|301|I VAS1 VAlyl-tRNA Synthetase 1104.0 0 1 0 0 1.2247919342520817 P07806 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.3262160718441009 0.5179711580276489 0.007291085552424192 0.011208600364625454 42.446320583978036 40.0 1.0 no 4534 chrVII_673138r 14106 essential YGR094W 955 - AACAGACCAATTAACTAATC V|325|L V|325|I W|323|C W|323|* VAS1 VAlyl-tRNA Synthetase 1104.0 0 0 0 0 -0.6364694660177901 P07806 0.9539830088615416 0.9574310183525084 0.8858469724655151 0.03374428674578667 0.04842906445264816 0.0 35.05180242729625 30.0 1.0 no 4535 chrVII_673232r 14109 essential YGR094W 1049 - CAACCTTTTCATCATAGCCT V|356|L V|356|I K|355|N silent|AAG>AAA|K|355 VAS1 VAlyl-tRNA Synthetase 1104.0 0 0 0 0 -0.5974230255244318 P07806 0.9539830088615416 0.9574310183525084 0.9355990290641784 0.046199843287467963 0.5398328304290771 0.014720646664500238 49.252513136885796 40.0 1.0 no 4536 chrVII_673233r 14110 essential YGR094W 1050 - TCAACCTTTTCATCATAGCC E|357|Q E|357|K V|356|L V|356|I VAS1 VAlyl-tRNA Synthetase 1104.0 0 0 0 0 0.1469021911151938 P07806 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.009540957398712637 0.04013347253203392 0.046199843287467963 0.5398328304290771 48.50875171670901 40.0 1.0 no 4537 chrVII_673554 14113 essential YGR094W 1368 + ATCAATATTTTGACTGACGA I|457|M silent|ATC>ATT|I|457 VAS1 VAlyl-tRNA Synthetase 1104.0 0 0 0 0 -0.10035805472422447 P07806 0.9598389863967896 0.015551657415926456 38.10803877158856 30.0 1.0 no 4538 chrVII_673599r 14117 essential YGR094W 1416 - CTCTTCATGCCTTGCCACTC K|478|N silent|AAG>AAA|K|478 M|477|I M|477|I VAS1 VAlyl-tRNA Synthetase 1104.0 0 0 0 0 0.8106347590220169 P07806 0.9355990290641784 0.9553959965705872 0.9553959965705872 0.01711135543882847 0.07797393202781677 0.07797393202781677 58.48573085733551 55.00000000000001 1.0 no 4539 chrVII_673630r 14118 essential YGR094W 1447 - CTGCTCAATGACCTTCTTTC E|488|D silent|GAG>GAA|E|488 E|488|Q E|488|K VAS1 VAlyl-tRNA Synthetase 1104.0 0 1 0 0 -0.6073265325131313 P07806 0.94931298494339 0.956179976463318 0.9475290179252625 0.221248522400856 0.17850324511528015 0.2352566123008728 49.284413585961325 45.0 1.0 no 4540 chrVII_673701 14120 essential YGR094W 1515 + ATTCCAACTTGTTCCAGATC P|507|A P|507|S P|507|R P|507|L VAS1 VAlyl-tRNA Synthetase 1104.0 0 0 0 0 -0.8937912528566061 P07806 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.09016470611095427 0.05019593611359596 0.05126595124602318 0.01156980823725462 47.866868074924184 40.0 1.0 no 4541 chrVII_673714r 14122 essential YGR094W 1531 - TTCAATAATGTCACCAGATC E|517|Q E|517|K VAS1 VAlyl-tRNA Synthetase 1104.0 0 0 0 0 -0.6507875553423971 P07806 0.956179976463318 0.9475290179252625 0.0 0.0 40.864359171959 35.0 1.0 no 4542 chrVII_673780r 14123 essential YGR094W 1597 - AACAACCTTAATAGCATCTT V|539|L V|539|I V|538|L V|538|I VAS1 VAlyl-tRNA Synthetase 1104.0 0 0 0 0 -0.16485287411002747 P07806 0.9539830088615416 0.9574310183525084 0.9539830088615416 0.9574310183525084 0.013695684261620043 0.0196967925876379 0.06377153098583221 0.13205790519714355 40.02182470541254 30.0 1.0 no 4543 chrVII_673871r 14129 essential YGR094W 1688 - GTCTGGAAATACACCAATCT R|569|T R|569|K VAS1 VAlyl-tRNA Synthetase 1104.0 0 0 0 0 -5.025456200188604 P07806 0.932735025882721 0.955805003643036 0.002969403984025121 0.05240492522716522 43.25053335224595 40.0 1.0 yes 4544 chrVII_674035r 14133 essential YGR094W 1852 - ATCTTGTTCCAGAGTAAATT D|624|H D|624|N VAS1 VAlyl-tRNA Synthetase 1104.0 0 0 0 0 0.6671581442470019 P07806 0.9486550092697144 0.956179976463318 0.0035782300401479006 0.014171754010021688 41.63561817922022 30.0 1.0 no 4545 chrVII_674074 14134 essential YGR094W 1888 + CCTGGTTCTCGTCCGGTTTG silent|ACC>ACG|T|630 silent|ACC>ACT|T|630 VAS1 VAlyl-tRNA Synthetase 1104.0 0 0 0 0 -0.24122002254370084 P07806 59.12979009289342 60.0 1.0 no 4546 chrVII_674104r 14137 essential YGR094W 1921 - CTTCTCTGGCCAACCCAAAG E|646|D silent|GAG>GAA|E|646 E|646|Q E|646|K VAS1 VAlyl-tRNA Synthetase 1104.0 0 0 0 0 -0.3009328216945089 P07806 0.94931298494339 0.956179976463318 0.9475290179252625 0.6714450120925903 0.2334408164024353 0.34585344791412354 52.42017231777851 55.00000000000001 1.0 no 4547 chrVII_674265 14143 essential YGR094W 2079 + TCTTTAGTCCGTGACGCTCA S|694|C S|694|F VAS1 VAlyl-tRNA Synthetase 1104.0 0 0 0 0 0.35948562358173536 P07806 0.945252001285553 0.9294660091400146 0.02197087183594704 0.008270662277936934 53.93859293758533 50.0 1.0 no 4548 chrVII_674610 14149 essential YGR094W 2424 + TATCAACCACCTGCCACTGA Q|810|E Q|810|* P|811|A P|811|S VAS1 VAlyl-tRNA Synthetase 1104.0 0 0 0 0 0.2155366296636604 P07806 0.9590039849281312 0.9562489986419678 0.9498909711837769 1.0 0.1022990494966507 0.06472335755825043 52.87409029678611 50.0 1.0 no 4549 chrVII_675875 14155 essential YGR095C 448 - AATCTTCAATTGCTCGGCAG K|155|N silent|AAG>AAA|K|155 L|154|F silent|TTG>TTA|L|154 RRP46 Ribosomal RNA Processing 223.0 0 0 0 0 -0.4199765100666455 P53256 0.30718564987182617 0.026511821895837784 0.814266562461853 2.130948543548584 0.4729659855365753 46.847128359024445 45.0 0.0 no 4550 chrVII_675876 14156 essential YGR095C 447 - ATCTTCAATTGCTCGGCAGT K|155|N silent|AAG>AAA|K|155 L|154|F silent|TTG>TTA|L|154 RRP46 Ribosomal RNA Processing 223.0 0 0 0 0 0.07936459124065771 P53256 0.30718564987182617 0.026511821895837784 0.814266562461853 2.130948543548584 0.4729659855365753 51.105871896436604 45.0 0.0 no 4551 chrVII_675919 14157 essential YGR095C 404 - TGTCTTTGATTATTGCAATA D|141|H D|141|N RRP46 Ribosomal RNA Processing 223.0 0 0 0 0 0.020805532070915168 P53256 0.06242407485842705 0.6286248564720154 0.5364941954612732 0.5837662220001221 39.008972797275256 25.0 0.0 no 4552 chrVII_676006 14159 essential YGR095C 317 - TACAACAACTTAGCTCTCTC C|112|S C|112|Y C|111|S C|111|Y RRP46 Ribosomal RNA Processing 223.0 0 0 0 0 0.2485527433676562 P53256 0.08110074698925017 0.0304548442363739 0.9027995467185974 0.14805492758750916 0.34894275665283203 13.896653175354006 1.0773600339889526 19.8336124420166 43.21065397201892 40.0 0.0 no 4553 chrVII_676007 14160 essential YGR095C 316 - ACAACAACTTAGCTCTCTCA C|112|S C|112|Y C|111|S C|111|Y RRP46 Ribosomal RNA Processing 223.0 0 0 0 0 -0.6203611185443874 P53256 0.08110074698925017 0.0304548442363739 0.9027995467185974 0.14805492758750916 0.34894275665283203 13.896653175354006 1.0773600339889526 19.8336124420166 45.119721726437426 40.0 0.0 no 4554 chrVII_676215 14167 essential YGR095C 108 - GGCAGTTCTTGTCTTGCTTT silent|CTG>CTC|L|42 silent|CTG>CTA|L|42 RRP46 Ribosomal RNA Processing 223.0 0 0 0 0 0.11098300021573657 P53256 55.29429786437288 45.0 0.0 no 4555 chrVII_683972 14171 essential YGR098C 3467 - TGCTCTCCATTAAGTCCTTC S|1162|T S|1162|N E|1161|D silent|GAG>GAA|E|1161 0 0 0 0 0.6927632984115076 Q03018 0.9512869715690612 0.9536849856376648 0.94931298494339 0.8750925660133362 0.7635100483894348 0.5828556418418884 52.752705515539844 45.0 0.0 no 4556 chrVII_683973 14172 essential YGR098C 3466 - GCTCTCCATTAAGTCCTTCT E|1161|D silent|GAG>GAA|E|1161 S|1162|T S|1162|N 0 0 0 0 -0.5600040170031935 Q03018 0.94931298494339 0.9512869715690612 0.9536849856376648 0.5828556418418884 0.8750925660133362 0.7635100483894348 54.73624357718649 45.0 0.0 no 4557 chrVII_684006 14173 essential YGR098C 3433 - TCTAATACTCTCTGTAATTG R|1151|T R|1151|K 0 0 0 0 0.02474448169531351 Q03018 0.932735025882721 0.955805003643036 0.4866004586219788 1.0 37.76462250319838 30.0 0.0 no 4558 chrVII_684334 14176 essential YGR098C 3105 - TGTCTTATATTCTTACCTCT R|1041|T R|1041|K 0 0 0 0 -1.0180257172821836 Q03018 0.932735025882721 0.955805003643036 0.04293539375066757 0.8190326094627379 45.44407713915609 30.0 0.0 no 4559 chrVII_684394 14179 essential YGR098C 3045 - AATCCTGTACTATGCTTGGA G|1021|A G|1021|E G|1021|R G|1021|R 0 0 0 0 1.0122367944276922 Q03018 0.9499930143356324 0.9438679814338684 0.941340982913971 0.941340982913971 1.0 0.1046820804476738 0.06370504945516586 0.06370504945516586 47.37001645534292 40.0 0.0 no 4560 chrVII_684552 14183 essential YGR098C 2887 - TACTCTATTGATTACATTTT V|969|L V|969|I R|968|T R|968|K 0 0 0 0 0.3853508701661759 Q03018 0.9539830088615416 0.9574310183525084 0.932735025882721 0.955805003643036 1.0 0.473345398902893 0.040935155004262924 1.0 36.64621494995225 20.0 0.0 no 4561 chrVII_684540r 14184 essential YGR098C 2896 + TCAATAGAGTACACAATATG I|966|M silent|ATC>ATT|I|966 0 0 0 0 -0.12346755085787695 Q03018 0.9598389863967896 0.012957382015883923 34.36123239638329 30.0 0.0 no 4562 chrVII_684564 14185 essential YGR098C 2875 - TACATTTTTGGGCATATATT V|965|L V|965|I 0 0 0 0 0.6594142492418299 Q03018 0.9539830088615416 0.9574310183525084 0.7201614975929259 0.8105372190475464 40.32734201112754 25.0 0.0 no 4563 chrVII_684630r 14186 essential YGR098C 2806 + AAACATTCCTACCTAATTTG T|937|R T|937|I 0 0 0 0 -0.5246612122484361 Q03018 0.9476869702339172 0.9472420215606691 0.00967437494546175 0.010482622310519218 39.290757124045 30.0 0.0 no 4564 chrVII_685234r 14193 essential YGR098C 2202 + ACAGCGTTTCAAATATATTT T|735|R T|735|I A|736|G A|736|V 0 0 0 0 0.4437529069903364 Q03018 0.9476869702339172 0.9472420215606691 0.9484469890594482 0.9504740238189696 0.3879250884056091 0.14197631180286407 0.5340511798858643 0.35287660360336304 37.878333205464116 25.0 0.0 no 4565 chrVII_685408 14196 essential YGR098C 2031 - AGCAAATAATTGTCGGCATA L|683|F silent|TTG>TTA|L|683 0 0 0 0 -0.3495190214568746 Q03018 0.9587849974632264 0.1222059652209282 41.1540569198566 35.0 0.0 no 4566 chrVII_685643 14201 essential YGR098C 1796 - TACTCATGTCCAGGTTCAAT S|605|T S|605|N M|604|I M|604|I 0 0 0 0 -1.1940164096842727 Q03018 0.9512869715690612 0.9536849856376648 0.9553959965705872 0.9553959965705872 0.5266577005386353 0.2460966110229492 0.0 0.0 48.0553043748244 40.0 0.0 no 4567 chrVII_685717 14202 essential YGR098C 1722 - AACGTATTATTTAGCTCTAA silent|ACG>ACC|T|580 silent|ACG>ACA|T|580 0 0 0 0 1.0195099722904912 Q03018 37.41819202629711 25.0 0.0 no 4568 chrVII_686320 14208 essential YGR098C 1119 - CTCAATATATCCTTATTTTT L|379|F silent|TTG>TTA|L|379 0 0 0 0 0.8743599665002113 Q03018 0.9587849974632264 0.18357039988040924 38.06356187764794 20.0 0.0 no 4569 chrVII_686376 14209 essential YGR098C 1063 - GACTAAACATTTTAATGTTG V|361|L V|361|I 0 0 0 0 0.8095805046683613 Q03018 0.9539830088615416 0.9574310183525084 0.7210119962692261 0.7167692184448242 32.92777680218637 25.0 0.0 no 4570 chrVII_686602r 14210 essential YGR098C 834 + TCCTATTCCATGCTGTACGA silent|TCC>TCG|S|279 silent|TCC>TCT|S|279 S|279|C S|279|F 0 0 0 0 0.9453652566107468 Q03018 0.945252001285553 0.9294660091400146 0.055022723972797394 0.08314217627048492 51.919667136304334 45.0 0.0 no 4571 chrVII_686660r 14212 essential YGR098C 776 + TCATAAAAATTATTTGGAGA H|260|D H|260|Y 0 0 0 0 1.0970964237556746 Q03018 0.9473130106925964 0.9489949941635132 0.4704174995422363 0.15122349560260773 30.996555863152768 20.0 0.0 no 4572 chrVII_686716 14213 essential YGR098C 723 - TTGCTAATGAACTTTTTAAA S|247|T S|247|N 0 0 0 0 0.014317206634844232 Q03018 0.9512869715690612 0.9536849856376648 0.23140355944633484 0.13811251521110535 33.133937753521764 20.0 0.0 no 4573 chrVII_687397 14227 essential YGR098C 42 - TTGCTAGTCATCGGAGTATT S|20|T S|20|N 0 0 0 0 -2.1297254523788447 Q03018 0.9512869715690612 0.9536849856376648 0.3806994557380676 0.324564665555954 47.56608486663612 40.0 0.0 yes 4574 chrVII_688039 14231 essential YGR099W 140 + ATCACTACCAGAAAGATCGA S|48|* S|48|L L|49|V silent|CTA>TTA|L|49 TEL2 TELomere maintenance 688.0 0 0 0 0 -0.005306712887633701 P53038 0.9298099875450134 0.9512209892272948 0.0 0.0 41.92841021328661 40.0 1.0 no 4575 chrVII_688104 14233 essential YGR099W 205 + GCCAAATTGTCACCTTCTCA Q|70|E Q|70|* C|69|W silent|TGC>TGT|C|69 TEL2 TELomere maintenance 688.0 0 0 0 0 -0.3657877961460312 P53038 0.9590039849281312 0.9286419749259948 0.0 0.010558698326349258 51.44422499423854 45.0 1.0 no 4576 chrVII_688379 14242 essential YGR099W 480 + ACAGATCCACCTGGGTTTTT T|161|R T|161|I P|163|A P|163|S TEL2 TELomere maintenance 688.0 0 0 0 0 0.04502038232155122 P53038 0.9476869702339172 0.9472420215606691 0.9562489986419678 0.9498909711837769 0.6041452288627625 0.3249645829200745 0.6082109808921814 0.5494761466979979 52.99035965560035 45.0 1.0 no 4577 chrVII_688432r 14243 essential YGR099W 536 - ACATATCTGCCGCTAGCACT M|185|I M|185|I D|184|H D|184|N TEL2 TELomere maintenance 688.0 0 0 0 0 0.28567348171663204 P53038 0.9553959965705872 0.9553959965705872 0.9486550092697144 0.956179976463318 1.0 1.0 0.07119864970445633 0.4099306762218475 54.03508287289259 50.0 1.0 no 4578 chrVII_688433r 14244 essential YGR099W 537 - AACATATCTGCCGCTAGCAC M|185|I M|185|I TEL2 TELomere maintenance 688.0 0 0 0 0 1.1168398598789353 P53038 0.9553959965705872 0.9553959965705872 1.0 1.0 50.588147083271906 50.0 1.0 no 4579 chrVII_688565r 14245 essential YGR099W 669 - GTCACGATAACTTGAATATA silent|GTG>GTC|V|229 silent|GTG>GTA|V|229 V|229|L V|229|M TEL2 TELomere maintenance 688.0 0 0 0 0 -0.028829255999989038 P53038 0.9539830088615416 0.9587630033493042 0.32303714752197266 0.07772094011306763 36.40216145967032 30.0 1.0 no 4580 chrVII_688726 14247 essential YGR099W 827 + CACGAAGTTTGTTAGCGCTT T|277|R T|277|M TEL2 TELomere maintenance 688.0 0 0 0 0 0.7108881980253541 P53038 0.9476869702339172 0.9502379894256592 0.5355587601661682 0.1189655214548111 47.81827034008603 45.0 1.0 no 4581 chrVII_688828 14248 essential YGR099W 929 + TCTCAATCATTCCCAGAGAG silent|CTC>CTG|L|311 silent|CTC>CTT|L|311 L|311|V L|311|F TEL2 TELomere maintenance 688.0 0 0 0 0 -0.34536619253396605 P53038 0.9512209892272948 0.9587849974632264 0.319680392742157 0.26104867458343506 48.01048408814762 45.0 1.0 no 4582 chrVII_688887r 14250 essential YGR099W 991 - TTCATTGCTACCTAAATGTT E|337|Q E|337|K TEL2 TELomere maintenance 688.0 0 0 0 0 0.1980933157505621 P53038 0.956179976463318 0.9475290179252625 0.05682009831070901 0.07816125452518463 42.280805592521226 30.0 1.0 no 4583 chrVII_689069 14253 essential YGR099W 1170 + TGCAATACCCAAACTGATGT C|391|W silent|TGC>TGT|C|391 TEL2 TELomere maintenance 688.0 0 0 0 0 1.1952662997925911 P53038 0.9286419749259948 0.019927741959691048 44.500720257751205 40.0 1.0 no 4584 chrVII_689077r 14254 essential YGR099W 1181 - TATCCTTACCCACATCAGTT D|400|H D|400|N K|399|N silent|AAG>AAA|K|399 TEL2 TELomere maintenance 688.0 0 1 0 0 0.6076583841274955 P53038 0.9486550092697144 0.956179976463318 0.9355990290641784 0.13776333630084991 0.7782149910926819 0.5313919186592102 51.4118778589376 40.0 1.0 no 4585 chrVII_695593 14263 essential YGR103W 176 + AACTACTTTTTACTATGCTA T|60|S T|60|I T|61|S T|61|I NOP7 NucleOlar Protein 605.0 0 0 0 0 0.5153512785176003 P53261 0.07725203037261963 0.09684592485427856 0.5027935504913329 0.006628591101616621 38.73910975267961 25.0 1.0 no 4586 chrVII_695640r 14266 essential YGR103W 226 - TTCTCTAAATTTAGCCAAAA E|82|Q E|82|K R|81|T R|81|K NOP7 NucleOlar Protein 605.0 0 0 0 0 -0.2440737510223171 P53261 0.2265298664569855 0.028115885332226757 0.0 0.0 36.42745022666412 25.0 1.0 no 4587 chrVII_695752 14269 essential YGR103W 335 + TACTTTAGACCATATTATCA T|113|S T|113|I NOP7 NucleOlar Protein 605.0 0 0 0 0 0.8985163557690571 P53261 0.6863037347793579 0.0678078755736351 39.1606079481221 25.0 1.0 no 4588 chrVII_695792r 14270 essential YGR103W 378 - TCAATATCCCTTATAGCATC D|133|H D|133|N NOP7 NucleOlar Protein 605.0 0 0 0 0 -0.5210550609181951 P53261 0.006968478206545114 0.03017033450305462 45.09177690841539 35.0 1.0 no 4589 chrVII_695985r 14272 essential YGR103W 571 - AACTTCTTCACCCTTAATAT V|197|L V|197|I E|196|Q E|196|K NOP7 NucleOlar Protein 605.0 0 0 0 0 -2.1430890439738777 P53261 0.04374400898814202 1.0 0.484904408454895 0.4687928855419159 43.21635717724206 30.0 1.0 yes 4590 chrVII_696152r 14276 essential YGR103W 738 - TCCTTTTTAAGATCCAATTT K|252|N silent|AAG>AAA|K|252 D|253|H D|253|N NOP7 NucleOlar Protein 605.0 0 0 0 0 -0.15078220634705136 P53261 0.15815135836601255 0.006127873901277781 0.03185265883803368 41.3246548745655 25.0 1.0 no 4591 chrVII_696244r 14277 essential YGR103W 830 - CGTCTTCCTCAATCTCAGTT D|283|H D|283|N E|282|Q E|282|K NOP7 NucleOlar Protein 605.0 0 0 0 0 -0.6465996145082453 P53261 0.0312759131193161 0.2548301815986633 0.5730022788047789 0.901561200618744 51.764080715933005 45.0 1.0 no 4592 chrVII_696301 14279 essential YGR103W 884 + GTCTGCCTTGAATGCCGATG S|296|C S|296|F A|297|G A|297|V NOP7 NucleOlar Protein 605.0 1 Series([], Name: modification, dtype: object) 0 0 0 1.1343581459211889 P53261 0.050199374556541436 0.04738367348909378 0.3691578209400177 0.3513828217983246 53.26718383365197 55.00000000000001 1.0 no 4593 chrVII_696548 14287 essential YGR103W 1131 + TTCTTGATCTTATCTTGTGG F|378|L silent|TTC>TTT|F|378 NOP7 NucleOlar Protein 605.0 0 0 0 0 -0.7638636846096722 P53261 0.0 44.201849113585304 35.0 1.0 no 4594 chrVII_696636 14290 essential YGR103W 1219 + TCACTCATCAAATTGTTGAC T|408|S T|408|I silent|GTC>GTG|V|407 silent|GTC>GTT|V|407 NOP7 NucleOlar Protein 605.0 0 0 0 0 0.15321063348984593 P53261 0.0 0.0 39.9904171481607 35.0 1.0 no 4595 chrVII_696775 14292 essential YGR103W 1358 + TCCACCTCACTTAAGCCCAT P|454|R P|454|L P|454|A P|454|S NOP7 NucleOlar Protein 605.0 0 0 0 0 -0.3161869307142413 P53261 0.0 0.0 0.0 0.0 56.36699610394862 50.0 1.0 no 4596 chrVII_697860 14298 high_effect YGR104C 489 - TCTGAAATTTGCAATGACCA D|170|H D|170|N 0 0 0 0 1.2456084259729812 P32585 0.9486550092697144 0.956179976463318 0.0 0.0 0.14309999346733093 0.12303999811410905 0.5396000146865845 0.3351599872112274 41.22131201041435 35.0 0.0 no 4597 chrVII_697918r 14300 high_effect YGR104C 428 + TGACATCATAGATGTCGACA D|144|E silent|GAC>GAT|D|144 I|145|M silent|ATC>ATT|I|145 0 0 0 0 -0.08354163105955557 P32585 0.9532920122146606 0.9598389863967896 1.0 0.18681879341602325 -0.8037999868392944 -0.3892000019550324 42.904224811438276 40.0 0.0 no 4598 chrVII_698051r 14301 high_effect YGR104C 295 + CGCTTAACTATGCTATGACA L|100|V L|100|F 0 0 0 0 -0.09773715488750867 P32585 0.9512209892272948 0.9587849974632264 0.9528576731681824 0.4539307355880737 0.27900001406669617 -0.3937999904155731 43.738118936390265 40.0 0.0 no 4599 chrVII_697997 14302 high_effect YGR104C 352 - TTCGTTTGTGCTGTTGAAGT E|124|Q E|124|K 0 0 0 0 -0.5142978368848033 P32585 0.956179976463318 0.9475290179252625 47.949713104325895 40.0 0.0 no 4600 chrVII_698125 14303 high_effect YGR104C 224 - CCATCATTGTTTCATCGATC M|81|I M|81|I M|80|I M|80|I 0 0 0 0 0.08296693756339568 P32585 0.9553959965705872 0.9553959965705872 0.9553959965705872 0.9553959965705872 0.18854522705078125 0.18854522705078125 0.227977067232132 0.227977067232132 -0.03099999949336052 -0.03099999949336052 -0.10199999809265137 -0.10199999809265137 46.69557085278905 40.0 0.0 no 4601 chrVII_698220 14308 high_effect YGR104C 129 - TCGACGTCGTAAGATGGATT E|50|Q E|50|K V|49|L V|49|I 0 0 0 0 -0.4509929634720456 P32585 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.18865860998630524 0.06689828634262085 0.2564294934272766 1.0 -0.028680000454187393 -0.03167999908328056 -0.5232800245285034 -0.5101799964904785 0.7839999794960022 0.7311999797821045 -0.8579999804496765 -0.6222000122070312 0.03147999942302704 -0.2827199995517731 -0.5477400422096252 -0.2924266755580902 44.63528491828259 45.0 0.0 no 4602 chrVII_698286r 14310 high_effect YGR104C 60 + TCAACTTTGACCACAATATC S|21|* S|21|L T|22|S T|22|I 0 0 0 0 -0.321665364923444 P32585 0.9298099875450134 0.9491789937019348 0.9472420215606691 0.019477106630802155 0.19253426790237427 0.0062617091462016106 -1.0805799961090088 0.32047998905181885 -1.310420036315918 -0.4018000066280365 -1.3941999673843384 40.43214468292013 35.0 0.0 no 4603 chrVII_718935 14312 essential YGR113W 42 + ACGGAATATCGTTTATCCAT T|15|R T|15|M DAM1 Duo1 And Mps1 interacting 343.0 0 0 0 0 -1.3215965656434312 P53267 0.0 0.0 43.35178641006207 35.0 1.0 no 4604 chrVII_719166 14318 essential YGR113W 273 + GCTGATCTTAATGAATCCCT A|92|G A|92|V L|94|V L|94|F DAM1 Duo1 And Mps1 interacting 343.0 0 0 0 0 0.4596848330163454 P53267 0.014017349109053612 1.0 0.07707594335079193 0.3887610137462616 46.96101748621231 40.0 1.0 no 4605 chrVII_719182r 14319 essential YGR113W 292 - ACCGTACAACAACGAACCTA G|104|R G|104|S G|104|A G|104|D DAM1 Duo1 And Mps1 interacting 343.0 0 0 0 0 -6.759207037088717 P53267 0.0 0.0 0.0 0.0 44.185761855624435 45.0 1.0 yes 4606 chrVII_719559 14326 essential YGR113W 666 + GTTCTAAATCCAACAAATAT L|224|V silent|CTA>TTA|L|224 DAM1 Duo1 And Mps1 interacting 343.0 0 0 0 0 0.24734442914420424 P53267 0.4431876838207245 34.885537789890925 25.0 1.0 no 4607 chrVII_720439r 14328 essential YGR116W 33 - ACTATTTCTTCCTCGTCCCT V|18|L V|18|I SPT6 SuPpressor of Ty's 1451.0 0 0 0 0 -5.445516299248951 P23615 0.8153456449508667 0.7741823196411133 56.636280974962176 45.0 1.0 yes 4608 chrVII_720487r 14329 essential YGR116W 81 - TCTCCTTCTTCTTCCTCACT G|33|A G|33|E E|34|Q E|34|K SPT6 SuPpressor of Ty's 1451.0 0 1 0 0 0.4995938631091397 P23615 1.0 0.8612391352653503 0.4762937426567078 0.6029464602470398 57.44125904783112 45.0 1.0 no 4609 chrVII_720689r 14330 essential YGR116W 283 - TAACAAATCCAAATCATCTT L|100|F silent|TTG>TTA|L|100 SPT6 SuPpressor of Ty's 1451.0 0 0 0 0 -0.9296275898927181 P23615 0.0 35.291885633338666 25.0 1.0 no 4610 chrVII_720736 14331 essential YGR116W 327 + ACCAAAGCGAGCTCCTCTTC silent|ACC>ACG|T|110 silent|ACC>ACT|T|110 T|110|S T|110|I SPT6 SuPpressor of Ty's 1451.0 0 0 0 0 0.33874940650585383 P23615 0.7186504602432251 0.20263917744159696 53.883913203259965 55.00000000000001 1.0 no 4611 chrVII_721043r 14338 essential YGR116W 637 - TTCTTGGATCCTCCTTTGTC E|219|Q E|219|K SPT6 SuPpressor of Ty's 1451.0 0 0 0 0 -0.2779322505547153 P23615 0.4657795131206513 0.8760316371917725 54.16962786710417 45.0 1.0 no 4612 chrVII_721059r 14339 essential YGR116W 653 - CTCTTAAAAGCTTCTTTTCT R|224|T R|224|K SPT6 SuPpressor of Ty's 1451.0 0 1 0 0 -0.056026730179309966 P23615 0.3548135757446289 0.9490591883659364 41.09258308225691 30.0 1.0 no 4613 chrVII_721088r 14340 essential YGR116W 682 - AATCTGTGTAGGTTGTTTGA Q|233|H silent|CAG>CAA|Q|233 SPT6 SuPpressor of Ty's 1451.0 0 1 0 0 -0.421053568219179 P23615 0.07428731769323349 44.463625952009686 35.0 1.0 no 4614 chrVII_721093 14341 essential YGR116W 684 + AAACAACCTACACAGATTAC Q|230|E Q|230|* P|231|A P|231|S SPT6 SuPpressor of Ty's 1451.0 0 1 0 0 -0.3607309804874006 P23615 1.0 0.9536184072494508 0.8110114932060242 37.541022711792266 35.0 1.0 no 4615 chrVII_721104 14342 essential YGR116W 695 + ACAGATTACTGGTCTATCGT Q|233|E Q|233|* SPT6 SuPpressor of Ty's 1451.0 0 1 0 0 -0.1991856849155942 P23615 0.7630575299263 46.197130947724865 40.0 1.0 no 4616 chrVII_721413 14344 essential YGR116W 1004 + CTACGGAAATATGTCATCGG Y|336|* silent|TAC>TAT|Y|336 SPT6 SuPpressor of Ty's 1451.0 0 0 0 0 -0.5140614623815267 P23615 41.83922986801929 45.0 1.0 no 4617 chrVII_721770 14350 essential YGR116W 1361 + TCAGAATACTGCATCTATTG Q|455|E Q|455|* SPT6 SuPpressor of Ty's 1451.0 0 0 0 0 -0.8976694241972352 P23615 0.11570098996162415 40.38106820867819 35.0 1.0 no 4618 chrVII_721869r 14352 essential YGR116W 1463 - TCTTACCAGTCTTTCCAGTG K|494|N silent|AAG>AAA|K|494 G|493|A G|493|D SPT6 SuPpressor of Ty's 1451.0 0 1 0 0 -3.2449719550132805 P23615 0.017245471477508545 0.7526586651802063 0.6246035695075989 52.58659775111181 45.0 1.0 yes 4619 chrVII_722036r 14357 essential YGR116W 1630 - TTCTATCACTTCTACTGGTT E|550|Q E|550|K silent|GTG>GTC|V|548 silent|GTG>GTA|V|548 SPT6 SuPpressor of Ty's 1451.0 0 0 0 0 0.2448095287573535 P23615 0.4919179379940033 0.672760546207428 46.407798142476686 35.0 1.0 no 4620 chrVII_722294 14367 essential YGR116W 1885 + GAACTCCAATGCACTTCCGT T|630|S T|630|I P|631|A P|631|S SPT6 SuPpressor of Ty's 1451.0 0 0 0 0 0.01665696902424919 P23615 0.9213382005691528 0.08675391227006912 0.09682334214448927 0.039461903274059296 51.40053508640528 50.0 1.0 no 4621 chrVII_722295 14368 essential YGR116W 1886 + AACTCCAATGCACTTCCGTA T|630|S T|630|I P|631|A P|631|S SPT6 SuPpressor of Ty's 1451.0 0 0 0 0 0.3663733542526909 P23615 0.9213382005691528 0.08675391227006912 0.09682334214448927 0.039461903274059296 49.74855155987086 45.0 1.0 no 4622 chrVII_722427 14370 essential YGR116W 2018 + ACTTGAAACTACCAATACCT L|674|V L|674|F SPT6 SuPpressor of Ty's 1451.0 0 0 0 0 -0.6899763058469353 P23615 0.035635393112897866 0.13721303641796112 41.566380712011274 35.0 1.0 no 4623 chrVII_722444r 14371 essential YGR116W 2038 - CCATTCTATTGCGATGTCCG W|686|S W|686|* E|685|Q E|685|K SPT6 SuPpressor of Ty's 1451.0 0 0 0 0 -1.2705664139614627 P23615 0.0 0.5438340306282043 0.9108244776725768 51.37131885926016 50.0 1.0 no 4624 chrVII_722481 14373 essential YGR116W 2072 + ACTGGCATTCAACCAAGCGA L|692|V silent|CTG>TTG|L|692 A|693|G A|693|V SPT6 SuPpressor of Ty's 1451.0 0 0 0 0 0.3949917035287217 P23615 0.35887908935546875 0.0962926670908928 1.0 49.697652144777116 50.0 1.0 no 4625 chrVII_722514r 14374 essential YGR116W 2108 - TGACTTCTTGAGATATATCC V|709|L V|709|I E|708|Q E|708|K SPT6 SuPpressor of Ty's 1451.0 0 0 0 0 -3.705559273889147 P23615 0.1207081452012062 0.6854908466339111 0.24578811228275302 0.3827224373817444 42.1219527424206 35.0 1.0 yes 4626 chrVII_722573r 14375 essential YGR116W 2167 - AAACTTATGGCGAACAGTCT K|728|N silent|AAG>AAA|K|728 SPT6 SuPpressor of Ty's 1451.0 0 0 0 0 -3.2223181865740664 P23615 0.5039800405502319 42.392945213921344 40.0 1.0 yes 4627 chrVII_722547 14376 essential YGR116W 2138 + AACAAAAAATTGTCAAAAAT T|714|R T|714|I SPT6 SuPpressor of Ty's 1451.0 0 0 0 0 -0.3626384582784412 P23615 1.0 0.016123440116643906 25.247772062706762 15.0 1.0 no 4628 chrVII_722616 14377 essential YGR116W 2207 + TCCATTCATTCCTAATGTCA P|737|R P|737|L P|737|A P|737|S SPT6 SuPpressor of Ty's 1451.0 0 0 0 0 0.07571728311366578 P23615 0.0 0.0 0.0 0.0 47.60549542475917 35.0 1.0 no 4629 chrVII_722669r 14379 essential YGR116W 2263 - TCCGAATCTACCCTGTCCAC G|761|R G|761|R G|761|A G|761|E SPT6 SuPpressor of Ty's 1451.0 0 0 0 0 -6.281487048156724 P23615 0.2128691673278809 0.2128691673278809 0.317041277885437 0.4258527755737305 55.6092028518089 55.00000000000001 1.0 yes 4630 chrVII_722707 14382 essential YGR116W 2298 + GCTGTCTACGTCAACAGAAA A|767|G A|767|V silent|GTC>GTG|V|768 silent|GTC>GTT|V|768 SPT6 SuPpressor of Ty's 1451.0 0 0 0 0 -1.0510703047620382 P23615 0.6989292502403259 0.05756254121661186 44.431478413455686 45.0 1.0 no 4631 chrVII_722801r 14383 essential YGR116W 2395 - GCTTTGAATGATATTATCCA S|805|T S|805|N SPT6 SuPpressor of Ty's 1451.0 0 0 0 0 -6.346701685946915 P23615 0.5858944654464722 0.8496455550193787 41.43653525604003 30.0 1.0 yes 4632 chrVII_722830r 14386 essential YGR116W 2424 - CCATTGATTCCGATGGCATT G|815|R G|815|S SPT6 SuPpressor of Ty's 1451.0 0 0 0 0 -1.3680638527305518 P23615 0.008100379258394241 0.13861066102981567 50.58290755598796 45.0 1.0 no 4633 chrVII_723369 14395 essential YGR116W 2960 + GACTATTTTTATGAATTCCG T|988|S T|988|I SPT6 SuPpressor of Ty's 1451.0 0 0 0 0 0.31653383609991353 P23615 0.19943316280841827 0.05551423504948616 38.9146281821802 30.0 1.0 no 4634 chrVII_723480 14398 essential YGR116W 3071 + AGACTACCATTTGGCCACCA D|1025|E silent|GAC>GAT|D|1025 Y|1026|* silent|TAC>TAT|Y|1026 SPT6 SuPpressor of Ty's 1451.0 0 0 0 0 0.4121914556482309 P23615 0.0 54.70978127890868 50.0 1.0 no 4635 chrVII_723486r 14399 essential YGR116W 3080 - CGGCAACCTTGGTGGCCAAA A|1033|P A|1033|T V|1032|L V|1032|I SPT6 SuPpressor of Ty's 1451.0 0 0 0 0 -0.8920895962029126 P23615 0.0 0.0 0.1209552064538002 0.07138983905315399 54.481666295252246 60.0 1.0 no 4636 chrVII_728502 14403 essential YGR119C 1150 - ATGCTTTTGTTGCAATTGTG K|389|N silent|AAG>AAA|K|389 NUP57 NUclear Pore 541.0 0 0 0 0 0.4944093218142688 P48837 0.0 44.45136706274104 35.0 0.0 no 4637 chrVII_728541 14404 essential YGR119C 1111 - GTTCAAAATTATTCTAGCTT L|376|F silent|TTG>TTA|L|376 NUP57 NUclear Pore 541.0 0 0 0 0 -0.014891006512203375 P48837 0.0 37.67134968238878 25.0 0.0 no 4638 chrVII_728666r 14408 essential YGR119C 983 + ACATGTACTTCAAGAAGAGT H|329|D H|329|Y NUP57 NUclear Pore 541.0 0 0 0 0 -0.9634959314780334 P48837 0.2540307939052582 0.013085490092635156 39.7255348795174 35.0 0.0 no 4639 chrVII_728744r 14411 essential YGR119C 905 + CACAACGAAAACAAAACTCA T|303|R T|303|I T|304|R T|304|M NUP57 NUclear Pore 541.0 0 0 0 0 -0.01688306971834547 P48837 0.008395165205001831 0.008352483622729778 0.5399618744850159 0.12234087288379668 33.366650052641035 35.0 0.0 no 4640 chrVII_728928r 14417 essential YGR119C 721 + CCACACAACCATCATTTGCT T|242|R T|242|I silent|TCC>TCG|S|241 silent|TCC>TCT|S|241 NUP57 NUclear Pore 541.0 0 0 0 0 -0.9724754012256684 P48837 0.5473131537437439 0.22979047894477844 49.929830235999354 45.0 0.0 no 4641 chrVII_729020r 14422 essential YGR119C 629 + CCAGAATAACAATACCCTTG Q|211|E Q|211|* NUP57 NUclear Pore 541.0 0 0 0 0 0.10457757992400574 P48837 0.8675083518028259 42.24276947534355 40.0 0.0 no 4642 chrVII_729064 14427 essential YGR119C 588 - CCATTAGTTGTTGATCCTTG G|203|R G|203|S NUP57 NUclear Pore 541.0 0 0 0 0 0.4419945586490873 P48837 0.0 0.0 47.90705401698097 40.0 0.0 no 4643 chrVII_729094r 14428 essential YGR119C 555 + GCGACTACGGGAGGCCTATT A|186|G A|186|V T|187|S T|187|I NUP57 NUclear Pore 541.0 0 0 0 0 -0.8375524818403267 P48837 0.4317733347415924 0.29418206214904785 0.7136466503143309 0.1234150379896164 55.54054598964461 60.0 0.0 no 4644 chrVII_729107r 14429 essential YGR119C 542 + TCAGAATACTACAGCGACTA Q|182|E Q|182|* NUP57 NUclear Pore 541.0 0 0 0 0 0.6441203106151763 P48837 1.0 42.122834594971955 40.0 0.0 no 4645 chrVII_729148r 14430 essential YGR119C 501 + ACATCTAACATGAATGCAGG T|168|R T|168|I S|169|C S|169|F NUP57 NUclear Pore 541.0 0 0 0 0 -0.16143434478048596 P48837 0.22962120175361636 0.09199512004852296 0.06599903106689453 0.06982069462537767 40.71722477632875 40.0 0.0 no 4646 chrVII_729151r 14431 essential YGR119C 498 + AACACATCTAACATGAATGC N|167|K silent|AAC>AAT|N|167 T|168|R T|168|I NUP57 NUclear Pore 541.0 0 0 0 0 -0.7988154575282465 P48837 0.2197776436805725 0.22962120175361636 0.09199512004852296 37.52159703086039 35.0 0.0 no 4647 chrVII_729186 14433 essential YGR119C 466 - GCCGCCCATCAGTGAGCCAG G|162|R G|162|S G|162|A G|162|D NUP57 NUclear Pore 541.0 0 0 0 0 -0.6916035128884658 P48837 0.3989337384700775 0.759352445602417 1.0 0.4089947938919067 64.77155302473506 70.0 0.0 no 4648 chrVII_729222 14434 essential YGR119C 430 - ACCAAATAAACCCCCACTTG G|150|R G|150|S G|150|A G|150|D NUP57 NUclear Pore 541.0 0 0 0 0 0.18171566219237106 P48837 0.04373396560549736 0.17958766222000122 0.22030259668827054 0.09575917571783066 47.31594847264261 45.0 0.0 no 4649 chrVII_729232r 14436 essential YGR119C 417 + AACAATAGTACCACAAGTGG N|140|K silent|AAC>AAT|N|140 NUP57 NUclear Pore 541.0 0 0 0 0 -0.5465134300969153 P48837 0.34795936942100525 40.45563108521429 40.0 0.0 no 4650 chrVII_729303 14442 essential YGR119C 349 - TCCAAATAACCCACCTCCAA G|123|R G|123|R G|123|A G|123|E NUP57 NUclear Pore 541.0 0 0 0 0 -0.4916639577402717 P48837 0.0 0.0 0.0 0.0 49.59699191786649 45.0 0.0 no 4651 chrVII_729280r 14443 essential YGR119C 369 + AACAAGCCAACTACCACAAC N|124|K silent|AAC>AAT|N|124 P|126|A P|126|S NUP57 NUclear Pore 541.0 0 0 0 0 0.4435411350429531 P48837 0.12948159873485565 0.3143469989299774 0.9024266004562378 43.441698762795 45.0 0.0 no 4652 chrVII_729316r 14447 essential YGR119C 333 + CCTCAACAATCCACCATTGG Q|113|E Q|113|* P|112|R P|112|L NUP57 NUclear Pore 541.0 0 0 0 0 -1.0284950915641229 P48837 0.5631679892539978 0.4843925535678864 0.6182374954223633 49.80518701517622 50.0 0.0 no 4653 chrVII_729319r 14448 essential YGR119C 330 + CAACCTCAACAATCCACCAT P|112|A P|112|S P|112|R P|112|L NUP57 NUclear Pore 541.0 0 0 0 0 -0.6028759819507782 P48837 0.774891197681427 0.9617414474487304 0.4843925535678864 0.6182374954223633 47.512878528891974 45.0 0.0 no 4654 chrVII_729418r 14454 essential YGR119C 231 + TTCGGTAATAAGCCTGCTCT F|78|L silent|TTC>TTT|F|78 NUP57 NUclear Pore 541.0 0 0 0 0 0.5127470370784895 P48837 0.27724510431289673 50.01311191652883 45.0 0.0 no 4655 chrVII_729475r 14457 essential YGR119C 174 + AATCAGGCCACAAATACTTT Q|60|E Q|60|* NUP57 NUclear Pore 541.0 0 0 0 0 0.747379392221371 P48837 1.0 42.355306486433726 35.0 0.0 no 4656 chrVII_729553r 14467 essential YGR119C 96 + CAACCTTCGGCTTCAGGATT P|34|A P|34|S P|34|R P|34|L NUP57 NUclear Pore 541.0 0 0 0 0 -0.4581336726896088 P48837 1.0 0.7563670873641968 0.364567756652832 0.5808819532394409 51.72794846625066 50.0 0.0 no 4657 chrVII_730233 14469 essential YGR120C 569 - ACTTATACAACTGCTCAATC K|196|N silent|AAG>AAA|K|196 COG2 Conserved Oligomeric Golgi complex 262.0 0 0 0 0 0.4164935450237098 P53271 0.9355990290641784 0.4273732304573059 0.4618799984455109 40.396538164982296 35.0 0.0 no 4658 chrVII_730281 14470 essential YGR120C 521 - GTTCTATACCGCACATTTCA E|180|Q E|180|K COG2 Conserved Oligomeric Golgi complex 262.0 0 0 0 0 0.3487201580280889 P53271 0.956179976463318 0.9475290179252625 0.16014480590820312 0.18354035913944244 -0.2683199942111969 -0.5773199796676636 48.76754778657085 40.0 0.0 no 4659 chrVII_730516 14472 essential YGR120C 286 - TTCATTTTCTTCATCTGTAT E|102|Q E|102|K COG2 Conserved Oligomeric Golgi complex 262.0 0 0 0 0 0.4940417750500832 P53271 0.956179976463318 0.9475290179252625 0.14681565761566162 0.030864719301462173 42.488056949996576 25.0 0.0 no 4660 chrVII_730599r 14473 essential YGR120C 200 + GTCTGGACTTTCACAAAAAA S|68|C S|68|F COG2 Conserved Oligomeric Golgi complex 262.0 0 0 0 0 0.25304335483275303 P53271 0.945252001285553 0.9294660091400146 0.030644625425338745 0.0292099267244339 37.86879450525356 35.0 0.0 no 4661 chrVII_730615 14474 essential YGR120C 187 - TCCAGACAAATCTCTAATAA G|69|R G|69|R G|69|A G|69|E COG2 Conserved Oligomeric Golgi complex 262.0 0 0 0 0 0.005310002770462868 P53271 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.5089279413223267 0.5089279413223267 0.7336084842681885 1.0 37.268609468686755 30.0 0.0 no 4662 chrVII_730699 14477 essential YGR120C 103 - AACATCGGTCCCATTAGTCT V|41|L V|41|I D|40|H D|40|N COG2 Conserved Oligomeric Golgi complex 262.0 0 0 0 0 0.2850918823074213 P53271 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 0.4437676668167114 1.0 0.05835920199751854 0.4646572768688202 51.636703964658864 45.0 0.0 no 4663 chrVII_730753 14479 essential YGR120C 49 - TAACTCTTTCGATATTTCTG E|22|D silent|GAG>GAA|E|22 E|22|Q E|22|K COG2 Conserved Oligomeric Golgi complex 262.0 0 0 0 0 0.8580252639755892 P53271 0.94931298494339 0.956179976463318 0.9475290179252625 1.0 0.0375409796833992 0.030137658119201664 38.91643779273642 30.0 0.0 no 4664 chrVII_730760 14480 essential YGR120C 42 - TTCGATATTTCTGCGGTTAC silent|TCG>TCC|S|20 silent|TCG>TCA|S|20 COG2 Conserved Oligomeric Golgi complex 262.0 0 0 0 0 -0.5273645412501157 P53271 45.62523487097695 40.0 0.0 no 4665 chrVII_748705 14482 essential YGR128C 1367 - TTTCAATAACTTCATTACAG E|462|Q E|462|K UTP8 U Three Protein 713.0 0 0 0 0 -0.5488678327704555 P53276 0.956179976463318 0.9475290179252625 0.5815145373344421 1.0 34.89854629376629 25.0 0.0 no 4666 chrVII_748886 14484 essential YGR128C 1186 - ATCAATATTAATTATTTCTA D|402|H D|402|N UTP8 U Three Protein 713.0 0 0 0 0 0.7092247773714877 P53276 0.9486550092697144 0.956179976463318 0.014354245737195015 0.2398024797439575 30.20268126670641 10.0 0.0 no 4667 chrVII_749145 14489 essential YGR128C 927 - GGACTGAGTTTATCCACCAT S|315|T S|315|N UTP8 U Three Protein 713.0 0 0 0 0 0.3831702158163791 P53276 0.9512869715690612 0.9536849856376648 0.3751514852046967 0.3406757116317749 50.650851691038035 45.0 0.0 no 4668 chrVII_749161r 14490 essential YGR128C 908 + ACAAGTTATTGAATTTCCGA Q|304|E Q|304|* UTP8 U Three Protein 713.0 0 0 0 0 0.2206148254521625 P53276 0.9590039849281312 1.0 39.764884550277095 30.0 0.0 no 4669 chrVII_749178 14491 essential YGR128C 894 - ACTTGTTGCAATTGGCAATG V|305|L V|305|I UTP8 U Three Protein 713.0 0 0 0 0 -0.1784186975097098 P53276 0.9539830088615416 0.9574310183525084 0.3615359961986542 0.28111040592193604 44.06482845438496 40.0 0.0 no 4670 chrVII_749247r 14493 essential YGR128C 822 + TCAAAGCTTTGTTATCAATT S|275|* S|275|L L|277|V L|277|F UTP8 U Three Protein 713.0 0 0 0 0 0.4639804214121939 P53276 0.9298099875450134 0.9512209892272948 0.9587849974632264 0.10991480946540833 0.25320181250572205 0.4009697139263153 37.819193966699856 25.0 0.0 no 4671 chrVII_749337r 14495 essential YGR128C 732 + TTGCTCGAGCTAACAGATTG L|246|V L|246|F silent|CTC>CTG|L|246 silent|CTC>CTT|L|246 UTP8 U Three Protein 713.0 0 0 0 0 -0.5620906617134468 P53276 0.9512209892272948 0.9587849974632264 0.4423070549964905 0.8236509561538696 45.107999733844004 45.0 0.0 no 4672 chrVII_749645 14497 essential YGR128C 427 - CTCACTCAGATGGTCATTTG E|149|Q E|149|K S|148|T S|148|N UTP8 U Three Protein 713.0 0 1 0 0 -1.697111247991748 P53276 0.956179976463318 0.9475290179252625 0.9512869715690612 0.9536849856376648 47.048042349404795 45.0 0.0 no 4673 chrVII_749689r 14498 essential YGR128C 380 + TACGCTAAATGTTATCACTA T|128|R T|128|M L|129|V silent|CTA>TTA|L|129 UTP8 U Three Protein 713.0 0 0 0 0 0.3355817479432865 P53276 0.9476869702339172 0.9502379894256592 0.9512209892272948 0.12307094782590865 0.05713437870144844 0.07861315459012985 38.71166612144884 30.0 0.0 no 4674 chrVII_767712r 14513 essential YGR140W 286 - TTTCTCTCCAGGCTTATCAT E|101|D silent|GAG>GAA|E|101 E|101|Q E|101|K CBF2 Centromere-Binding Factor 956.0 0 0 0 0 0.9367211087313844 P32504 51.96888478706553 40.0 1.0 no 4675 chrVII_767889 14514 essential YGR140W 460 + TCACCAAGCTTCATACCCAT T|155|S T|155|I silent|GTC>GTG|V|154 silent|GTC>GTT|V|154 CBF2 Centromere-Binding Factor 956.0 0 0 0 0 -0.12253522976293013 P32504 0.35825037956237793 0.627713143825531 1.4248000383377075 -1.0460000038146973 52.25743538902049 45.0 1.0 no 4676 chrVII_767892r 14515 essential YGR140W 466 - TATCCAATGGGTATGAAGCT W|161|C W|161|* W|161|S W|161|* CBF2 Centromere-Binding Factor 956.0 0 0 0 0 -4.163279265408766 P32504 0.045258637517690666 0.19739824533462524 3.1073999404907227 3.00819993019104 45.23883080366767 40.0 1.0 yes 4677 chrVII_767978r 14516 essential YGR140W 552 - TTCAAAGACACTTTCAATAA L|190|F silent|TTG>TTA|L|190 CBF2 Centromere-Binding Factor 956.0 0 0 0 0 0.8456112297587699 P32504 0.059653837233781815 -0.1348000019788742 33.92814204586017 25.0 1.0 no 4678 chrVII_768142r 14517 essential YGR140W 716 - TGTCCCTTTTACCGAGCTTG D|245|H D|245|N R|244|S silent|AGG>AGA|R|244 CBF2 Centromere-Binding Factor 956.0 0 0 0 0 0.22204813969923826 P32504 0.12212003022432327 0.4880748987197876 0.6718727946281433 0.2879999876022339 -0.2931999862194061 1.2455999851226809 54.741092167092525 50.0 1.0 no 4679 chrVII_768320r 14525 essential YGR140W 894 - CCATCCCCTTTCGAAACAGA G|305|R G|305|S D|304|H D|304|N CBF2 Centromere-Binding Factor 956.0 0 0 0 0 0.8675537855470931 P32504 0.0 0.0 0.009176853112876415 0.02743334136903286 2.2985999584198 2.7985999584198 3.990600109100342 2.0218000411987305 51.76847841117621 50.0 1.0 no 4680 chrVII_768514 14529 essential YGR140W 1085 + TAACCTTGTTTACCCAACTT N|363|K silent|AAC>AAT|N|363 L|364|V L|364|F CBF2 Centromere-Binding Factor 956.0 0 0 0 0 -0.3966570097912807 P32504 0.987898290157318 1.0 0.2190149426460266 -1.1987999677658079 1.10479998588562 2.370800018310547 1.141577959060669 2.062295913696289 46.3454973022196 35.0 1.0 no 4681 chrVII_768613r 14532 essential YGR140W 1187 - AGTCGAACGGTATTTTGTCA D|402|H D|402|N CBF2 Centromere-Binding Factor 956.0 0 0 0 0 -3.798394326918052 P32504 0.0 0.0 19.099000930786133 1.9562000036239624 45.349634917059404 40.0 1.0 yes 4682 chrVII_768694 14533 essential YGR140W 1265 + GGACCCTTTTCCGCCTCCAA D|423|E silent|GAC>GAT|D|423 P|424|A P|424|S CBF2 Centromere-Binding Factor 956.0 0 0 0 0 0.3169547663376792 P32504 1.0 0.7238883376121521 0.7053170800209045 1.2130000591278076 0.7329999804496765 1.0252000093460083 61.91632506179264 60.0 1.0 no 4683 chrVII_769085r 14539 essential YGR140W 1659 - TCAGATTCTTGTTTTTGAGT E|560|Q E|560|K CBF2 Centromere-Binding Factor 956.0 0 1 0 0 -0.9351734888952647 P32504 43.33845826718283 30.0 1.0 no 4684 chrVII_769086r 14540 essential YGR140W 1660 - CTCAGATTCTTGTTTTTGAG E|560|Q E|560|K CBF2 Centromere-Binding Factor 956.0 0 1 0 0 0.8459748015068438 P32504 42.60261860273522 35.0 1.0 no 4685 chrVII_769112r 14543 essential YGR140W 1686 - TCAAGTTGACTCATTTGTAA D|569|H D|569|N CBF2 Centromere-Binding Factor 956.0 0 1 0 0 0.038883396305546984 P32504 0.08347509056329727 0.3521020710468292 39.43545429978161 30.0 1.0 no 4686 chrVII_781939r 14548 essential YGR145W 175 - ACTCACTTTAATCTTATTGG silent|GTG>GTC|V|64 silent|GTG>GTA|V|64 S|65|T S|65|N ENP2 Essential Nuclear Protein 707.0 0 0 0 1 -0.4259933800760442 P48234 0.9512869715690612 0.9536849856376648 1.0 0.013256537728011608 39.54803216965821 30.0 1.0 no 4687 chrVII_781828 14550 essential YGR145W 61 + TTTCAAGATCACTTCCAGAC S|22|* S|22|L ENP2 Essential Nuclear Protein 707.0 0 0 0 0 -1.2209439572975271 P48234 0.9298099875450134 0.05468546599149704 44.47037832366175 40.0 1.0 no 4688 chrVII_781942r 14551 essential YGR145W 178 - TCTACTCACTTTAATCTTAT R|66|T R|66|K S|65|T S|65|N ENP2 Essential Nuclear Protein 707.0 0 0 0 0 0.18766227574830768 P48234 0.932735025882721 0.955805003643036 0.9512869715690612 0.9536849856376648 0.15454494953155518 0.6415476799011229 1.0 0.013256537728011608 39.01305652294195 25.0 1.0 no 4689 chrVII_782051 14553 essential YGR145W 284 + ACACACAGATGCTGAAAACG H|96|Q silent|CAC>CAT|H|96 H|96|D H|96|Y ENP2 Essential Nuclear Protein 707.0 0 0 0 0 0.5853174023709964 P48234 0.9588389992713928 0.9473130106925964 0.9489949941635132 0.02151940017938614 0.04108970612287522 0.011483192443847656 40.102562108091384 45.0 1.0 no 4690 chrVII_782077 14555 essential YGR145W 310 + TCACTATTCTCTCTGACGAT T|105|S T|105|I F|104|L silent|TTC>TTT|F|104 ENP2 Essential Nuclear Protein 707.0 0 0 0 0 0.2545811725573753 P48234 0.9491789937019348 0.9472420215606691 0.9387490153312684 0.6006612181663513 0.5392663478851318 0.0 46.03479296938491 40.0 1.0 no 4691 chrVII_782166 14556 essential YGR145W 399 + ACCACAAGAATTCCTAAATT silent|ACC>ACG|T|134 silent|ACC>ACT|T|134 T|134|S T|134|I ENP2 Essential Nuclear Protein 707.0 0 0 0 0 1.4101131781969538 P48234 0.9491789937019348 0.9472420215606691 0.2407554090023041 0.017355931922793392 38.99331337853067 30.0 1.0 no 4692 chrVII_782167 14557 essential YGR145W 400 + CCACAAGAATTCCTAAATTT T|135|R T|135|I silent|ACC>ACG|T|134 silent|ACC>ACT|T|134 ENP2 Essential Nuclear Protein 707.0 0 0 0 0 -0.7287422077297808 P48234 0.9476869702339172 0.9472420215606691 0.006216054782271385 0.10255339741706848 38.82760426379196 30.0 1.0 no 4693 chrVII_782178r 14558 essential YGR145W 414 - ACTAAACTTCTCCCAAATTT V|145|L V|145|I S|143|T S|143|N ENP2 Essential Nuclear Protein 707.0 0 0 0 0 0.8104098147059906 P48234 0.9539830088615416 0.9574310183525084 0.9512869715690612 0.9536849856376648 0.06091136112809181 0.08171524107456207 1.0 0.2635584771633148 40.98821127482535 30.0 1.0 no 4694 chrVII_782253 14559 essential YGR145W 486 + TACAGGTTGAACTTGGAAAA Y|163|* silent|TAC>TAT|Y|163 ENP2 Essential Nuclear Protein 707.0 0 0 0 0 -1.957973982973353 P48234 37.43255490627161 35.0 1.0 no 4695 chrVII_782365 14566 essential YGR145W 598 + AAACAAATGTAGTGGAATTC T|201|R T|201|I ENP2 Essential Nuclear Protein 707.0 0 0 0 0 -0.3699651191275072 P48234 0.9476869702339172 0.9472420215606691 0.2052144855260849 0.07188770174980164 33.489426346594826 30.0 1.0 no 4696 chrVII_782467r 14569 essential YGR145W 703 - TAACCCGTCATTACGGAAAC silent|GGG>GGC|G|240 silent|GGG>GGA|G|240 G|240|A G|240|E ENP2 Essential Nuclear Protein 707.0 0 0 0 0 0.09483523783424884 P48234 0.9499930143356324 0.9438679814338684 0.1521150767803192 0.005954641848802567 43.841495768321806 45.0 1.0 no 4697 chrVII_782481 14570 essential YGR145W 714 + GACGGGTTAACTTTTGCATG D|239|E silent|GAC>GAT|D|239 ENP2 Essential Nuclear Protein 707.0 0 0 0 0 0.4501365281321772 P48234 0.9532920122146606 0.015596437267959118 45.582887749845845 45.0 1.0 no 4698 chrVII_782550 14571 essential YGR145W 783 + CCTTCCATTATTAAAGACCA P|262|R P|262|L S|263|C S|263|F ENP2 Essential Nuclear Protein 707.0 0 0 0 0 -1.1415863105004875 P48234 0.9432820081710817 0.9430609941482544 0.945252001285553 0.9294660091400146 0.006733829155564308 0.008887817151844501 0.12501265108585358 0.8097947835922241 44.530887021075564 35.0 1.0 no 4699 chrVII_782784 14573 essential YGR145W 1017 + ACATATTATATTCCAAGTTT T|340|R T|340|I ENP2 Essential Nuclear Protein 707.0 0 0 0 0 0.15747057736325454 P48234 0.9476869702339172 0.9472420215606691 0.024005603045225143 0.025411086156964302 37.51907169107068 20.0 1.0 no 4700 chrVII_782984 14577 essential YGR145W 1217 + TAACACTGAACTTTACGATA N|407|K silent|AAC>AAT|N|407 T|408|S T|408|I ENP2 Essential Nuclear Protein 707.0 0 1 0 0 0.3124010264420444 P48234 0.9439849853515624 0.9491789937019348 0.9472420215606691 0.2690949141979217 0.7186678647994995 0.08605458587408066 36.14254701789628 30.0 1.0 no 4701 chrVII_783165 14579 essential YGR145W 1398 + AAACGTGGTGATAAAGTTGC R|468|G R|468|C ENP2 Essential Nuclear Protein 707.0 0 1 0 0 0.9501063906045322 P48234 0.8994590044021606 0.8926740288734436 0.3669779598712921 0.05031073465943337 39.716039866557935 40.0 1.0 no 4702 chrVII_783301r 14580 essential YGR145W 1537 - ACGTTTAGCAGCACCTTCTT R|519|P R|519|H ENP2 Essential Nuclear Protein 707.0 0 0 0 0 0.29438595922650684 P48234 0.9099509716033936 0.9570810198783876 0.0741642490029335 0.03991873562335968 53.073808709065936 45.0 1.0 no 4703 chrVII_786272r 14584 essential YGR147C 626 + CATCGTTAGAGTACCCCTGA I|210|M silent|ATC>ATT|I|210 NAT2 N-terminal AcetylTransferase 288.0 0 0 0 0 -1.0478869931803436 P37293 0.9598389863967896 0.07186467200517654 53.11416940028136 50.0 0.0 no 4704 chrVII_786312 14585 essential YGR147C 589 - GCCATACGCAATTAGCAATT G|203|R G|203|S G|203|A G|203|D NAT2 N-terminal AcetylTransferase 288.0 0 0 0 0 -0.5968152521444063 P37293 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 45.942327545535186 40.0 0.0 no 4705 chrVII_786530 14591 essential YGR147C 371 - TCTTCTCTTCACCTAGTGAG K|130|N silent|AAG>AAA|K|130 E|129|D silent|GAG>GAA|E|129 NAT2 N-terminal AcetylTransferase 288.0 0 0 0 0 0.18276474612452548 P37293 0.9355990290641784 0.94931298494339 0.11815932393074036 0.4199016690254211 50.440252899097906 45.0 0.0 no 4706 chrVII_786813r 14598 essential YGR147C 85 + CCGTATCCCATACACTGCGC silent|ACC>ACG|T|29 silent|ACC>ACT|T|29 S|31|C S|31|F NAT2 N-terminal AcetylTransferase 288.0 0 0 0 0 0.7501821944920353 P37293 0.945252001285553 0.9294660091400146 57.11583527708388 60.0 0.0 no 4707 chrVII_786879r 14600 essential YGR147C 19 + GTGCTTCACCAGTTTTCAAG A|8|G A|8|V S|9|* S|9|L NAT2 N-terminal AcetylTransferase 288.0 0 0 0 0 1.1119709897646108 P37293 0.9484469890594482 0.9504740238189696 0.9298099875450134 49.86307160971928 45.0 0.0 no 4708 chrVII_798650 14603 high_effect YGR155W 107 + ACCACAAATTTATGCTAAGC P|37|R P|37|L P|37|A P|37|S CYS4 CYStathionine beta-synthase 507.0 0 0 0 0 -0.4991455305434394 P32582 0.896930992603302 0.9032179713249208 0.9201790094375609 0.9116989970207214 0.005374286789447069 0.008516882546246052 0.18302293121814728 0.038174718618392944 40.864964426438924 35.0 1.0 no 4709 chrVII_798712r 14607 high_effect YGR155W 172 - AGCTTCTTCCACCATAGACT A|64|P A|64|T E|63|Q E|63|K CYS4 CYStathionine beta-synthase 507.0 0 0 0 0 -0.9589211230953758 P32582 0.9321290254592896 0.9238370060920716 0.97645902633667 0.9644089937210084 0.0 0.0 0.03422945365309715 0.026341252028942108 4.040999889373778 1.8356000185012815 53.075086650800024 45.0 1.0 no 4710 chrVII_798783 14611 high_effect YGR155W 240 + ACTTCTGGTAACACCGGTAT T|81|S T|81|I S|82|C S|82|F CYS4 CYStathionine beta-synthase 507.0 0 0 0 0 -2.2625345278363227 P32582 0.9913139939308168 0.9893620014190674 0.9879119992256165 0.9685909748077391 0.0 0.0 0.0027965214103460308 0.0011349619599059224 48.94953202909773 45.0 1.0 yes 4711 chrVII_798810 14612 high_effect YGR155W 267 + GCTTTAATCGGCGCCATCAA A|90|G A|90|V CYS4 CYStathionine beta-synthase 507.0 0 0 0 0 -0.031502593636151384 P32582 0.922241985797882 0.92146897315979 0.05583403632044792 0.004655021242797375 1.5959999561309814 2.4916000366210938 51.55527363221643 50.0 1.0 no 4712 chrVII_798917 14614 high_effect YGR155W 374 + AACTCCAACTGCTGCTGCCT T|126|S T|126|I P|127|A P|127|S CYS4 CYStathionine beta-synthase 507.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.6200332188850075 P32582 0.9103760123252868 0.9084240198135376 0.9314339756965636 0.9229540228843688 0.1677241027355194 0.00609288876876235 0.0 0.0 56.59416999344614 55.00000000000001 1.0 no 4713 chrVII_799032r 14617 high_effect YGR155W 492 - GTACCAAAGTAATGAGCTTC G|170|A G|170|D G|170|R G|170|S CYS4 CYStathionine beta-synthase 507.0 0 0 0 0 0.05126315163922422 P32582 0.9656509757041932 0.9535760283470154 0.9477360248565674 0.9668909907341005 0.9755409359931946 0.6515916585922241 0.6461066603660583 0.953496754169464 42.25580401235254 40.0 1.0 no 4714 chrVII_799067r 14618 high_effect YGR155W 527 - TCAAGTCTTCTAGCTGTCTT L|182|F silent|TTG>TTA|L|182 D|181|H D|181|N CYS4 CYStathionine beta-synthase 507.0 0 0 0 0 0.03811627846869989 P32582 0.9867290258407592 0.965224027633667 0.97645902633667 0.11281300336122513 0.518956184387207 8.438199996948242 49.614495162701985 40.0 1.0 no 4715 chrVII_799117 14620 high_effect YGR155W 574 + TTGCTGGTGCTGGTACTGGT A|193|G A|193|V CYS4 CYStathionine beta-synthase 507.0 0 0 0 0 0.6710235384745273 P32582 0.9672009944915771 0.9664270281791688 0.0015806695446372032 0.351187139749527 -4.875999927520752 10.729999542236328 57.9076376934072 55.00000000000001 1.0 no 4716 chrVII_799156r 14621 high_effect YGR155W 616 - ATTCTGTTCTTTCAAGTACT Q|211|H silent|CAG>CAA|Q|211 CYS4 CYStathionine beta-synthase 507.0 0 1 0 0 0.05245763918964436 P32582 0.9766640067100524 0.7223883867263794 43.35166787079596 30.0 1.0 no 4717 chrVII_799226r 14624 high_effect YGR155W 686 - TCTTATTCAAGTTTTCAGGT K|235|N silent|AAG>AAA|K|235 CYS4 CYStathionine beta-synthase 507.0 0 0 0 0 -0.4078872755905136 P32582 0.95727801322937 0.4407074153423309 43.297020158279736 30.0 1.0 no 4718 chrVII_799254 14626 high_effect YGR155W 711 + ATCACTGACTACAAAGTTGA I|238|M silent|ATC>ATT|I|238 T|239|S T|239|I CYS4 CYStathionine beta-synthase 507.0 0 0 0 0 -0.03771039890953271 P32582 0.9787610173225404 0.9665899872779846 0.9646379947662354 0.1088174283504486 0.7243741750717163 0.18915003538131714 -0.5705999732017517 39.52924042593286 35.0 1.0 no 4719 chrVII_799368 14628 high_effect YGR155W 825 + AGACAATTGATTTCTAACGA Q|277|E Q|277|* CYS4 CYStathionine beta-synthase 507.0 0 1 0 0 -0.06553442131909637 P32582 0.9786580204963684 0.1248168796300888 36.815884144770045 30.0 1.0 no 4720 chrVII_799451r 14633 high_effect YGR155W 911 - CATCTTCAGTCAGTTCAGGG D|310|H D|310|N E|309|Q E|309|K CYS4 CYStathionine beta-synthase 507.0 0 0 0 0 0.14792524764568618 P32582 0.965224027633667 0.97645902633667 0.97645902633667 0.9644089937210084 0.010302584618330002 0.10403644293546677 0.2119219154119492 0.697641134262085 51.58546262603414 50.0 1.0 no 4721 chrVII_799454r 14634 high_effect YGR155W 914 - CATCATCTTCAGTCAGTTCA D|311|H D|311|N D|310|H D|310|N CYS4 CYStathionine beta-synthase 507.0 0 0 0 0 1.1849325811432525 P32582 0.965224027633667 0.97645902633667 0.965224027633667 0.97645902633667 0.014062702655792236 0.02829196490347385 0.010302584618330002 0.10403644293546677 0.18780000507831573 -1.176800012588501 48.68829660800185 40.0 1.0 no 4722 chrVII_799455r 14635 high_effect YGR155W 915 - ACATCATCTTCAGTCAGTTC V|312|L V|312|I D|311|H D|311|N CYS4 CYStathionine beta-synthase 507.0 0 0 0 0 0.0328186750142071 P32582 0.9693499803543092 0.9770190119743348 0.965224027633667 0.97645902633667 0.09725932031869887 0.055819537490606315 0.014062702655792236 0.02829196490347385 0.18780000507831573 -1.176800012588501 47.75899388326594 40.0 1.0 no 4723 chrVII_799486 14637 high_effect YGR155W 943 + CCATATTCCCAGATTCCATC silent|GCC>GCG|A|315 silent|GCC>GCT|A|315 CYS4 CYStathionine beta-synthase 507.0 0 0 0 0 0.14344367524656948 P32582 52.544860747759905 45.0 1.0 no 4724 chrVII_799580 14640 high_effect YGR155W 1037 + CCGTTTTGACTCTTCAAAGC R|347|G R|347|C CYS4 CYStathionine beta-synthase 507.0 0 1 0 0 0.7568218041980616 P32582 0.9288319945335388 0.9288759827613832 0.22416876256465912 0.03151919692754745 47.038527949348286 45.0 1.0 no 4725 chrVII_800638 14645 essential YGR156W 92 + GAACCAAGATATAATTACTT N|32|K silent|AAC>AAT|N|32 Q|33|E Q|33|* PTI1 PTa1p Interacting protein 425.0 0 0 0 0 -1.5039510602316557 P39927 0.9597960114479064 0.987945020198822 0.3648200631141663 0.4786895215511322 34.623939002734915 25.0 1.0 no 4726 chrVII_800641r 14646 essential YGR156W 98 - CGACCGAAGTAATTATATCT V|39|L V|39|I silent|TCG>TCC|S|38 silent|TCG>TCA|S|38 PTI1 PTa1p Interacting protein 425.0 0 0 0 0 -0.034402395481172236 P39927 0.9138749837875366 0.9215430021286012 0.05576394498348236 0.3969277739524841 39.80538803696436 35.0 1.0 no 4727 chrVII_800708r 14650 essential YGR156W 165 - CCGGTTAGTTTACCAGTTCT G|62|R G|62|S PTI1 PTa1p Interacting protein 425.0 0 0 0 0 0.7186341671926357 P39927 0.9563270211219788 0.9744809865951538 0.0748492181301117 0.6775506734848022 53.00450449543621 45.0 1.0 no 4728 chrVII_800912r 14652 essential YGR156W 369 - AGCTCCAAACCCGCCTCGAA E|129|D silent|GAG>GAA|E|129 E|129|Q E|129|K PTI1 PTa1p Interacting protein 425.0 0 0 0 0 -0.2423596769621291 P39927 0.9535670280456544 0.961425006389618 0.9493749737739564 0.6160570383071899 0.2575011849403381 0.13558143377304074 56.46953752381928 60.0 1.0 no 4729 chrVII_800913r 14653 essential YGR156W 370 - TAGCTCCAAACCCGCCTCGA E|129|D silent|GAG>GAA|E|129 E|129|Q E|129|K PTI1 PTa1p Interacting protein 425.0 0 0 0 0 -1.0128951840964806 P39927 0.9535670280456544 0.961425006389618 0.9493749737739564 0.6160570383071899 0.2575011849403381 0.13558143377304074 57.59267874918601 60.0 1.0 no 4730 chrVII_800936r 14655 essential YGR156W 393 - ACTTCTGTCACCATTTCGAA V|138|L V|138|I E|137|Q E|137|K PTI1 PTa1p Interacting protein 425.0 0 0 0 0 0.9568496565058529 P39927 0.9131360054016112 0.9208049774169922 0.9202449917793274 0.9081959724426271 0.0 0.0 0.1059526652097702 0.1168893501162529 47.35991521716034 40.0 1.0 no 4731 chrVII_801401r 14662 essential YGR156W 858 - TCATTAGAAGGTACATGCAA E|293|Q E|293|K PTI1 PTa1p Interacting protein 425.0 0 0 0 0 1.0165751682133712 P39927 0.9315000176429749 0.9194509983062744 0.4846078455448151 0.7479472756385803 40.61865377858106 35.0 1.0 no 4732 chrVII_805967r 14673 essential YGR158C 32 + CCCTGCTGCTGCCAAGCCAA P|12|R P|12|L P|12|A P|12|S MTR3 MRNA TRansport 250.0 0 0 0 0 0.3154650359033759 P48240 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 62.642529342659365 65.0 0.0 no 4733 chrVII_829423 14679 high_effect YGR165W 307 + CCAAGAAGCCATTGCAACTA silent|ACC>ACG|T|103 silent|ACC>ACT|T|103 MRPS35 Mitochondrial Ribosomal Protein, Small subunit 345.0 0 0 0 0 0.7011115972190841 P53292 46.68901328391832 45.0 1.0 no 4734 chrVII_829423r 14680 high_effect YGR165W 310 - CCTTAGTTGCAATGGCTTCT R|110|T R|110|K MRPS35 Mitochondrial Ribosomal Protein, Small subunit 345.0 0 0 0 0 -0.010113135784305616 P53292 0.932735025882721 0.955805003643036 0.597704291343689 0.9314159154891968 51.983002983969186 45.0 1.0 no 4735 chrVII_829431r 14681 high_effect YGR165W 318 - CCATCATACCTTAGTTGCAA G|113|R G|113|R D|112|H D|112|N MRPS35 Mitochondrial Ribosomal Protein, Small subunit 345.0 0 0 0 0 0.14447400928697013 P53292 0.941340982913971 0.941340982913971 0.9486550092697144 0.956179976463318 0.6557639837265015 0.6557639837265015 0.15427306294441226 0.5947980880737305 48.15162226809355 40.0 1.0 no 4736 chrVII_829431 14682 high_effect YGR165W 315 + CCATTGCAACTAAGGTATGA P|106|R P|106|L Q|108|E Q|108|* MRPS35 Mitochondrial Ribosomal Protein, Small subunit 345.0 0 0 0 0 -0.9708083412496564 P53292 0.9432820081710817 0.9430609941482544 0.9590039849281312 0.4305473268032074 0.4312941133975983 1.0 43.92497718469177 40.0 1.0 no 4737 chrVII_829587 14686 high_effect YGR165W 471 + TTCGAAGAGATTACTGTGGA F|158|L silent|TTC>TTT|F|158 MRPS35 Mitochondrial Ribosomal Protein, Small subunit 345.0 0 0 0 0 0.01262130259761507 P53292 0.9387490153312684 0.3803682625293732 42.041201820458866 40.0 1.0 no 4738 chrVII_829814 14690 high_effect YGR165W 698 + TCCTGTTCCGCAAAAGACTT P|234|R P|234|L P|234|A P|234|S MRPS35 Mitochondrial Ribosomal Protein, Small subunit 345.0 0 0 0 0 0.25905563892012995 P53292 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 48.60228255272143 45.0 1.0 no 4739 chrVII_829869r 14693 high_effect YGR165W 756 - GCTGCATCAACAGGCCCAAA A|259|P A|259|T A|258|P A|258|T MRPS35 Mitochondrial Ribosomal Protein, Small subunit 345.0 0 0 0 0 0.2120237752484387 P53292 0.9573720097541808 0.9523990154266356 0.9573720097541808 0.9523990154266356 0.02070688270032406 0.021389750763773918 0.0 0.0 53.518742031040524 55.00000000000001 1.0 no 4740 chrVII_832474r 14694 high_effect YGR167W 21 - TCAATGTTTTGATCTTCCAA D|14|H D|14|N CLC1 Clathrin Light Chain 233.0 0 1 0 0 0.4030994906277097 P17891 0.9486550092697144 0.956179976463318 42.18188399148204 30.0 1.0 no 4741 chrVII_832563 14695 high_effect YGR167W 107 + AGACGAGTTCAAGACTGAAC D|37|E silent|GAC>GAT|D|37 CLC1 Clathrin Light Chain 233.0 0 1 0 0 -0.32478813755478525 P17891 0.9532920122146606 0.06470292806625366 40.771729740065105 45.0 1.0 no 4742 chrVII_832611r 14697 high_effect YGR167W 158 - TTTCGTCATCATCTTTGGCG E|59|Q E|59|K D|58|H D|58|N CLC1 Clathrin Light Chain 233.0 0 0 0 0 0.12396227118694847 P17891 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.11988836526870728 0.1197081208229065 0.026367148384451863 0.09101328253746033 49.72230605598776 45.0 1.0 no 4743 chrVII_832657 14698 high_effect YGR167W 201 + CCAGATATCAACTCCGCAAA P|68|R P|68|L CLC1 Clathrin Light Chain 233.0 0 0 0 0 1.0666945545602808 P17891 0.9432820081710817 0.9430609941482544 0.014558065682649612 0.01950829476118088 45.94771734977485 45.0 1.0 no 4744 chrVII_832790r 14703 high_effect YGR167W 337 - TTCAGAACGATCCTCTTTAA E|119|Q E|119|K CLC1 Clathrin Light Chain 233.0 0 0 0 0 0.3990830529936066 P17891 0.956179976463318 0.9475290179252625 0.427868515253067 0.5760530233383179 42.39772514121836 35.0 1.0 no 4745 chrVII_832839 14705 high_effect YGR167W 383 + TGCTGTAGAGATTCACGAAA A|129|G A|129|V CLC1 Clathrin Light Chain 233.0 0 1 0 0 -0.14970013327932566 P17891 0.9484469890594482 0.9504740238189696 0.14632035791873932 0.14710171520709991 41.69719099631885 40.0 1.0 no 4746 chrVII_843068r 14706 essential YGR172C 501 + TTCAATACAGCGTCCATCTT F|168|L silent|TTC>TTT|F|168 0 0 0 0 0.23257342520007315 P53039 0.9502609968185424 0.6127352118492126 48.11492042769277 40.0 0.0 no 4747 chrVII_843179r 14708 essential YGR172C 390 + GTTCATTTTGGATATATCTA H|132|D H|132|Y 0 0 0 0 0.6352783661681849 P53039 0.8342199921607971 0.8292719721794128 0.02288595587015152 0.026247046887874603 39.504109414471095 25.0 0.0 no 4748 chrVII_843290 14710 essential YGR172C 282 - ACACCACTACCAAAACGTAT G|100|A G|100|D V|101|L V|101|M 0 0 0 0 1.2247932365522107 P53039 0.9681630134582521 0.9567970037460328 0.9768360257148744 0.928928017616272 0.7531214356422424 0.6898833513259888 0.388313502073288 0.0977398008108139 43.18101973541769 40.0 0.0 no 4749 chrVII_843293r 14711 essential YGR172C 276 + ATACCAATACGTTTTGGTAG P|94|A P|94|S P|94|R P|94|L 0 0 0 0 0.3881164114465603 P53039 0.8351309895515442 0.9062460064888 0.8017969727516174 0.8358439803123474 0.0 0.0 0.0 0.0 41.6937789109661 35.0 0.0 no 4750 chrVII_843356 14713 essential YGR172C 216 - ATTCCAATTTCCTCCAGTAA G|78|A G|78|E G|78|R G|78|R 0 0 0 0 0.8395314946246165 P53039 0.9067869782447816 0.8937749862670898 0.7933369874954224 0.7933369874954224 0.026025138795375824 0.07065945118665695 0.005702625960111618 0.005702625960111618 47.8490405998283 35.0 0.0 no 4751 chrVII_843369r 14718 essential YGR172C 200 + TCCACATGAACCTCCATTAC P|68|R P|68|L P|68|A P|68|S 0 0 0 0 -0.2374896012511296 P53039 0.8303819894790649 0.9131720066070556 1.0039399862289429 0.9864360094070436 0.09211238473653792 0.06461151689291 0.4899397194385529 0.4274304807186127 48.97604446721607 45.0 0.0 no 4752 chrVII_843395r 14719 essential YGR172C 174 + TTACATGCTCTTTCAACTAA H|60|D H|60|Y 0 0 0 0 0.7943226606737949 P53039 0.975000023841858 1.0036900043487549 0.5166419148445129 0.07666169852018356 40.46123711300486 30.0 0.0 no 4753 chrVII_843508r 14722 essential YGR172C 61 + CACAATTTGCCGTTCCCCAA Q|22|E Q|22|* 0 0 0 0 -0.1939217582325291 P53039 0.9809970259666444 1.0 53.90780414417589 50.0 0.0 no 4754 chrVII_843509r 14724 essential YGR172C 60 + GCACAATTTGCCGTTCCCCA Q|22|E Q|22|* A|21|G A|21|V 0 0 0 0 -0.4008070832773541 P53039 0.9809970259666444 1.0111600160598757 0.9749590158462524 1.0 0.600400447845459 0.5581503510475159 58.97847121580469 55.00000000000001 0.0 no 4755 chrVII_847336r 14728 essential YGR175C 1065 + GTCTTGTTGATTAAGAAAAT silent|GTC>GTG|V|356 silent|GTC>GTT|V|356 ERG1 ERGosterol biosynthesis 496.0 0 0 0 0 -0.12023498402227112 P32476 33.965512549211375 25.0 0.0 no 4756 chrVII_847565 14737 essential YGR175C 839 - TCCAACTCTTGATATCAGCT W|286|S W|286|* W|286|C W|286|* ERG1 ERGosterol biosynthesis 496.0 0 1 0 0 -1.35912756043522 P32476 0.8858469724655151 0.8858469724655151 0.07232062518596649 0.03191988542675972 47.71550602019392 40.0 0.0 no 4757 chrVII_847772r 14744 essential YGR175C 629 + TATCTTTTCACGTTTCAGAA I|211|M silent|ATC>ATT|I|211 ERG1 ERGosterol biosynthesis 496.0 0 0 0 0 1.144520865594604 P32476 0.9598389863967896 0.10588899254798888 41.253155800026775 30.0 0.0 no 4758 chrVII_847795r 14746 essential YGR175C 606 + CACTTGACATTTATCTGTGA H|203|Q silent|CAC>CAT|H|203 ERG1 ERGosterol biosynthesis 496.0 0 0 0 0 1.0854204771434548 P32476 0.9588389992713928 0.5501168370246887 42.45559490416729 35.0 0.0 no 4759 chrVII_847797 14747 essential YGR175C 607 - GTCACAGATAAATGTCAAGT D|209|H D|209|N C|208|S C|208|Y ERG1 ERGosterol biosynthesis 496.0 0 0 0 0 -3.681492302126076 P32476 0.9486550092697144 0.956179976463318 0.9421560168266296 0.9290120005607604 0.0 0.0 0.3537685871124268 0.10374652594327928 39.25963852368358 35.0 0.0 yes 4760 chrVII_847886r 14750 essential YGR175C 515 + TAACTGTATTGAGATATTGA N|173|K silent|AAC>AAT|N|173 ERG1 ERGosterol biosynthesis 496.0 0 0 0 0 1.111296557972457 P32476 0.9439849853515624 0.02367364801466465 34.979810748198645 25.0 0.0 no 4761 chrVII_848018r 14751 essential YGR175C 383 + AGACAGCACTATTCACATCA D|129|E silent|GAC>GAT|D|129 S|130|R silent|AGC>AGT|S|130 ERG1 ERGosterol biosynthesis 496.0 0 0 0 0 0.2873087385275101 P32476 0.9532920122146606 0.9417110085487366 1.0 0.4869107902050018 45.64028205950035 40.0 0.0 no 4762 chrVII_848212 14755 essential YGR175C 192 - CTCAATGCTCTAACACCACC L|70|F silent|TTG>TTA|L|70 ERG1 ERGosterol biosynthesis 496.0 0 0 0 0 -0.3577363801443874 P32476 0.9587849974632264 0.022259319201111797 49.40975866321425 50.0 0.0 no 4763 chrVII_848317r 14759 essential YGR175C 84 + ATCGGTCCATGTGTTGCTAC I|29|M silent|ATC>ATT|I|29 P|31|A P|31|S ERG1 ERGosterol biosynthesis 496.0 0 0 0 0 -0.10337522166595436 P32476 0.9598389863967896 0.9562489986419678 0.9498909711837769 0.0922003760933876 0.5273083448410034 1.0 53.498549208659476 50.0 0.0 no 4764 chrVII_853983r 14764 essential YGR179C 890 + TCCAGTACTTAACAAAGCAA P|298|R P|298|L P|298|A P|298|S OKP1 Outer Kinetochore Protein 406.0 0 0 0 0 -0.8153991680538848 P53298 0.017444010823965073 0.01642206870019436 0.10958202928304672 0.29364803433418274 40.34082644746832 35.0 0.0 no 4765 chrVII_854073 14765 essential YGR179C 803 - ACTTCCTAGTTTCCTCCAAA K|274|N silent|AAG>AAA|K|274 R|273|S silent|AGG>AGA|R|273 OKP1 Outer Kinetochore Protein 406.0 0 0 0 0 -0.15851407419080987 P53298 0.29200130701065063 0.027017764747142792 50.66401825446735 40.0 0.0 no 4766 chrVII_854203 14767 essential YGR179C 673 - ATCTCTTTCCGATATCCTAG D|231|H D|231|N R|230|T R|230|K OKP1 Outer Kinetochore Protein 406.0 0 0 0 0 0.19544250522593407 P53298 0.0 0.0 0.04208020493388176 0.43931108713150013 48.268447023693845 40.0 0.0 no 4767 chrVII_854591r 14778 essential YGR179C 282 + AAACAACTTCGATTTGAGGT Q|96|E Q|96|* L|97|V L|97|F OKP1 Outer Kinetochore Protein 406.0 0 0 0 0 1.7101469045740036 P53298 0.8961954712867737 1.0 0.13684692978858948 39.41642355652056 35.0 0.0 no 4768 chrVII_854595r 14779 essential YGR179C 278 + ATCTAAACAACTTCGATTTG S|94|C S|94|F OKP1 Outer Kinetochore Protein 406.0 0 0 0 0 0.012471989768677541 P53298 0.07620136439800262 0.0757235512137413 35.815654802416866 30.0 0.0 no 4769 chrVII_854790 14781 essential YGR179C 86 - TATCGCTTTCAGAGGAACTT D|35|H D|35|N S|34|T S|34|N OKP1 Outer Kinetochore Protein 406.0 0 0 0 0 -2.009753193217548 P53298 0.16779662668704987 0.7272956967353821 0.6508519053459167 0.5382131338119507 45.118576978898886 40.0 0.0 no 4770 chrVII_855817 14787 high_effect YGR180C 465 - GCAGCCTTATGCTTGACTTC A|162|P A|162|T A|161|P A|161|T RNR4 RiboNucleotide Reductase 345.0 0 1 0 0 0.5374558645303622 P49723 0.12797999382019046 0.2632444202899933 0.015492200851440431 0.018702203407883644 4.54334020614624 0.6029000282287598 3.485280036926269 0.33348000049591064 3.835033893585205 0.2060759961605072 2.876872062683105 0.5671120285987854 54.142039327488135 50.0 0.0 no 4771 chrVII_855845 14788 high_effect YGR180C 437 - TGGCAATTTCCTTGAATAGA A|152|P A|152|T RNR4 RiboNucleotide Reductase 345.0 0 1 0 0 0.010869376568616656 P49723 0.046268656849861145 0.095959834754467 0.6314600110054016 0.4972400069236755 -0.22203600406646729 0.22491799294948575 42.93696271076129 35.0 0.0 no 4772 chrVII_856163r 14796 high_effect YGR180C 116 + TATCAAATACCACGAAATCT I|40|M silent|ATC>ATT|I|40 RNR4 RiboNucleotide Reductase 345.0 0 0 0 0 -0.6120246650900718 P49723 0.004211693536490202 0.5812199711799622 1.127311944961548 36.672481764440185 30.0 0.0 no 4773 chrVII_866730 14799 essential YGR185C 771 - CCATTCTCTTCGACGTTACC G|264|R G|264|S E|262|D silent|GAG>GAA|E|262 TYS1 TYrosyl-tRNA Synthetase 394.0 0 0 0 0 0.3458939678597551 P36421 0.941340982913971 0.951104998588562 0.94931298494339 0.003063820069655776 0.06763587146997453 0.8023186326026917 4.830999851226807 0.9812800288200378 0.1761000007390976 51.8803806486029 50.0 0.0 no 4774 chrVII_866729 14800 essential YGR185C 772 - ACCATTCTCTTCGACGTTAC G|264|R G|264|S G|264|A G|264|D TYS1 TYrosyl-tRNA Synthetase 394.0 0 0 0 0 0.6911453957971523 P36421 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.003063820069655776 0.06763587146997453 0.0384984128177166 0.0060121361166238785 4.830999851226807 0.9812800288200378 0.5582000017166138 5.547999858856201 48.677255150217256 45.0 0.0 no 4775 chrVII_866772 14802 essential YGR185C 729 - ATCTTTTTCTTAACTTGCTT K|249|N silent|AAG>AAA|K|249 TYS1 TYrosyl-tRNA Synthetase 394.0 0 1 0 0 0.4946626519138803 P36421 0.9355990290641784 0.0 1.6499199867248535 42.190216042143454 25.0 0.0 no 4776 chrVII_867115r 14810 essential YGR185C 383 + GCTAACTCCAGACTATACCA L|129|V silent|CTA>TTA|L|129 T|130|S T|130|I TYS1 TYrosyl-tRNA Synthetase 394.0 0 0 0 0 1.141473977754127 P36421 0.9512209892272948 0.9491789937019348 0.9472420215606691 0.0333966426551342 1.0 0.012202696874737741 0.538860023021698 -0.21661999821662906 0.1731799989938736 0.1628199964761734 1.5477999448776243 -0.2427999973297119 0.22740000486373899 48.96249399120563 45.0 0.0 no 4777 chrVII_867188 14811 essential YGR185C 313 - GCTTCTCAAGATAGCTTTGA S|111|T S|111|N R|110|T R|110|K TYS1 TYrosyl-tRNA Synthetase 394.0 0 0 0 0 0.7315864488799195 P36421 0.9512869715690612 0.9536849856376648 0.932735025882721 0.955805003643036 0.05541916191577912 0.03807662427425385 0.6956916451454163 0.8751901984214783 0.9528999924659728 2.9961800575256348 0.3983800113201141 -0.2865200042724609 46.61434350700489 40.0 0.0 no 4778 chrVII_867387r 14818 essential YGR185C 111 + AGACATTTGAAATTATACTG H|39|D H|39|Y TYS1 TYrosyl-tRNA Synthetase 394.0 0 0 0 0 -0.498429672114925 P36421 0.9473130106925964 0.9489949941635132 0.7149590849876404 0.03870267421007157 0.2105800062417984 -0.12929999828338626 0.2306399941444397 -0.05347999930381775 32.842782989043485 25.0 0.0 no 4779 chrVII_867788 14820 essential YGR186W 14 + TCCACCAGGCAGTAGAAACG P|6|R P|6|L P|6|A P|6|S TFG1 Transcription Factor G 735.0 0 0 0 0 -1.0234150940631002 P41895 49.95523924104043 55.00000000000001 1.0 no 4780 chrVII_867831r 14825 essential YGR186W 60 - ATTCTGTCTCTTTTAATGAA R|26|T R|26|K TFG1 Transcription Factor G 735.0 0 1 0 0 -0.4717494325024379 P41895 38.582977406295576 25.0 1.0 no 4781 chrVII_867963r 14831 essential YGR186W 192 - TCTCTCTCTTCAGCATACTC R|70|T R|70|K E|71|Q E|71|K TFG1 Transcription Factor G 735.0 0 0 0 0 0.06233455928443354 P41895 51.615572447479046 45.0 1.0 no 4782 chrVII_868015r 14833 essential YGR186W 244 - AACATTGCTCCTGCCAGCAT V|88|L V|88|I TFG1 Transcription Factor G 735.0 0 0 0 0 0.4735860236546569 P41895 0.6349027752876282 0.3959634602069855 55.38560970890706 50.0 1.0 no 4783 chrVII_868077r 14834 essential YGR186W 306 - TCCTTTGGAATAGCTCTTAA K|108|N silent|AAG>AAA|K|108 E|109|Q E|109|K TFG1 Transcription Factor G 735.0 0 0 0 0 0.5336059200832791 P41895 0.3797745704650879 0.25844746828079224 0.2152007818222046 44.438583207533725 35.0 1.0 no 4784 chrVII_868179r 14836 essential YGR186W 408 - TCCTTCCTATGCAGTCTTAC K|142|N silent|AAG>AAA|K|142 D|143|H D|143|N TFG1 Transcription Factor G 735.0 0 0 0 0 -0.5842042597778763 P41895 0.0 0.0 0.0 53.30438142325744 45.0 1.0 no 4785 chrVII_868342 14838 essential YGR186W 568 + TCAATAATACTGTTAAAGAT silent|CTC>CTG|L|190 silent|CTC>CTT|L|190 TFG1 Transcription Factor G 735.0 0 0 0 0 -0.4598140924288249 P41895 30.863725051283666 20.0 1.0 no 4786 chrVII_868422 14840 essential YGR186W 648 + TCCTCCATTCCTACTGTAAC silent|TCC>TCG|S|217 silent|TCC>TCT|S|217 S|217|C S|217|F TFG1 Transcription Factor G 735.0 0 0 0 0 0.04816267835649664 P41895 51.55567800600704 45.0 1.0 no 4787 chrVII_868616r 14851 essential YGR186W 845 - TGACCATTCCAACTTTAGTA V|288|L V|288|I M|287|I M|287|I TFG1 Transcription Factor G 735.0 0 1 0 0 -0.612069848811009 P41895 45.170098160878354 35.0 1.0 no 4788 chrVII_868732r 14857 essential YGR186W 961 - CCTTCTCAAATTTCCTCGTT R|327|T R|327|K R|326|T R|326|K TFG1 Transcription Factor G 735.0 0 0 0 0 0.05440704436097099 P41895 0.0140198627486825 0.6465520858764648 0.02152529545128345 1.0 49.248342043591954 40.0 1.0 no 4789 chrVII_868818r 14858 essential YGR186W 1047 - TCAAAATCTTCCATAACCCA D|356|H D|356|N TFG1 Transcription Factor G 735.0 0 0 0 0 -0.011213334807297692 P41895 0.01149948313832283 0.054585553705692284 43.631840548939635 35.0 1.0 no 4790 chrVII_868935r 14859 essential YGR186W 1164 - AACTTATAAACCTTATCAGC K|394|N silent|AAG>AAA|K|394 TFG1 Transcription Factor G 735.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.1878940187120299 P41895 0.01439614500850439 38.19638691284921 30.0 1.0 no 4791 chrVII_869114 14860 essential YGR186W 1340 + CGTCGCTGATCAACAAGCTA silent|GTC>GTG|V|448 silent|GTC>GTT|V|448 A|449|G A|449|V TFG1 Transcription Factor G 735.0 0 0 0 0 0.01006885276990832 P41895 0.3809170722961426 0.2859366238117218 47.65063201985679 50.0 1.0 no 4792 chrVII_880699 14872 essential YGR191W 279 + CATCTTTTAACTCTAGCTGT L|95|V L|95|F HIP1 HIstidine Permease 603.0 0 0 0 0 0.3808600490746713 P06775 0.1349392533302307 0.015195049345493315 44.61171221469817 35.0 1.0 no 4793 chrVII_880701 14874 essential YGR191W 281 + TCTTTTAACTCTAGCTGTCG L|95|V L|95|F HIP1 HIstidine Permease 603.0 0 0 0 0 0.3236658489132804 P06775 0.1349392533302307 0.015195049345493315 45.5598027340526 40.0 1.0 no 4794 chrVII_880781 14879 essential YGR191W 361 + CGGCCAGTTTAGTTATTGAT A|122|G A|122|V silent|GCC>GCG|A|122 silent|GCC>GCT|A|122 HIP1 HIstidine Permease 603.0 0 0 0 0 -0.2722200020293 P06775 0.1868862509727478 0.0077695962972939014 47.99896002327336 40.0 1.0 no 4795 chrVII_880934 14884 essential YGR191W 514 + ACTTAAACTATTTAGCACAA N|172|K silent|AAC>AAT|N|172 HIP1 HIstidine Permease 603.0 0 0 0 0 0.2700174302036053 P06775 0.011800941079854963 35.56084407941199 25.0 1.0 no 4796 chrVII_880962 14885 essential YGR191W 542 + TCTTCTACCCTTGGAATTAG L|182|V L|182|F L|183|V silent|CTA>TTA|L|183 HIP1 HIstidine Permease 603.0 0 0 0 0 0.10339281530057336 P06775 1.0 0.010169290006160736 0.013864999637007713 46.603065497052285 40.0 1.0 no 4797 chrVII_881057r 14888 essential YGR191W 640 - CAACATATTAGCCAGTGCAA M|219|I M|219|I HIP1 HIstidine Permease 603.0 0 0 0 0 -4.8104218248351485 P06775 0.12775398790836334 0.12775398790836334 44.80560732205265 40.0 1.0 yes 4798 chrVII_881137 14889 essential YGR191W 717 + ATCATTGGCTTTACTATCTT I|240|M silent|ATC>ATT|I|240 HIP1 HIstidine Permease 603.0 0 0 0 0 -0.41772009574168906 P06775 0.011835281737148762 44.366683981654994 30.0 1.0 no 4799 chrVII_881360r 14901 essential YGR191W 943 - TCTCTTTGCTGCCTTGGGAA K|320|N silent|AAG>AAA|K|320 R|321|T R|321|K HIP1 HIstidine Permease 603.0 0 0 0 0 0.8936881107573345 P06775 0.0051304432563483715 0.006058814004063606 0.0343252457678318 55.091197822589436 50.0 1.0 no 4800 chrVII_881484 14904 essential YGR191W 1064 + GGACGCTGCCTCATCTCCTC D|356|E silent|GAC>GAT|D|356 A|357|G A|357|V HIP1 HIstidine Permease 603.0 0 0 0 0 -1.5702072452712987 P06775 0.034388184547424316 0.04139521718025208 0.22985647618770602 62.31268408100635 65.0 1.0 no 4801 chrVII_888986 14916 essential YGR195W 104 + TGCAGACGGTTCATCCTACA A|36|G A|36|V D|37|E silent|GAC>GAT|D|37 SKI6 SuperKIller 246.0 0 0 0 0 1.5995350469354233 P46948 0.050013694912195206 0.01679389178752899 0.01252805907279253 0.9912099838256836 1.6392259597778318 0.4369400143623352 1.445099949836731 0.9877200126647948 52.4558141673084 50.0 1.0 no 4802 chrVII_889151r 14918 essential YGR195W 272 - GAACACGCCTTTCATTCTTG V|97|L V|97|I R|96|P R|96|H SKI6 SuperKIller 246.0 0 0 0 0 -0.3060381901709855 P46948 0.5369520783424377 0.6758885979652405 0.006962466053664684 0.007874136790633202 -1.2404979467391968 -0.3311919867992401 0.702564001083374 0.3391039967536926 -1.885200023651123 -1.7419600486755369 1.0653599500656128 0.36340001225471497 1.5959000587463381 0.12479334324598312 47.68049783675889 45.0 1.0 no 4803 chrVII_889081r 14919 essential YGR195W 202 - TACGTTCAATAAAGCCTTTG V|74|L V|74|I L|72|F silent|TTG>TTA|L|72 SKI6 SuperKIller 246.0 0 0 0 0 0.2915041899178721 P46948 0.09700338542461397 0.24653199315071106 0.016828427091240883 0.2471099942922592 -0.9262580275535583 -0.4198099970817566 0.16986000537872314 40.51192237791065 35.0 1.0 no 4804 chrVII_889234r 14923 essential YGR195W 355 - CTCGATATCGATAACTGTTC E|125|Q E|125|K SKI6 SuperKIller 246.0 0 0 0 0 1.0725478502044874 P46948 0.3368707895278931 0.3613830208778381 -0.686735987663269 -0.920643985271454 0.5092446804046631 0.40260925889015203 41.3833058551981 40.0 1.0 no 4805 chrVII_889402r 14928 essential YGR195W 523 - AGCATTTTCTTCTAATGAAT A|181|P A|181|T SKI6 SuperKIller 246.0 0 0 0 0 0.818388142128936 P46948 0.18300014734268188 0.3198018968105316 2.6951000690460205 -0.3856860101222992 2.5350799560546875 0.31613999605178833 38.44275711663437 25.0 1.0 no 4806 chrVII_894960r 14940 essential YGR198W 270 - TCCACTAGTTTTGTAATCTC silent|GTG>GTC|V|96 silent|GTG>GTA|V|96 E|97|Q E|97|K YPP1 alpha-sYnuclein Protective Protein 817.0 0 0 0 0 -0.6012640330640187 P46951 0.6527650952339172 0.8790259361267091 44.682875837039774 35.0 1.0 no 4807 chrVII_895028r 14943 essential YGR198W 338 - ACCGCTGCGATTCCTGAAAT R|119|P R|119|Q silent|CGG>CGC|R|119 silent|CGG>CGA|R|119 YPP1 alpha-sYnuclein Protective Protein 817.0 0 0 0 0 -0.06669968565443607 P46951 0.09582615643739699 0.2547226846218109 50.57089157677386 50.0 1.0 no 4808 chrVII_895088 14944 essential YGR198W 395 + ATCGCAAAAAACAGCACTTA S|133|W S|133|L Q|134|E Q|134|* YPP1 alpha-sYnuclein Protective Protein 817.0 0 0 0 0 0.2297589061328325 P46951 0.018300961703062057 0.2553103268146515 1.0 38.39658744950025 35.0 1.0 no 4809 chrVII_895102 14945 essential YGR198W 409 + CACTTATGGAGCAGTATGAT L|138|V L|138|F YPP1 alpha-sYnuclein Protective Protein 817.0 0 0 0 0 -1.3240627288713882 P46951 0.8364473581314087 0.719534158706665 44.35561650076961 40.0 1.0 no 4810 chrVII_895142r 14946 essential YGR198W 452 - AAACTAGACCACGGTAGTAC V|157|L V|157|I YPP1 alpha-sYnuclein Protective Protein 817.0 0 0 0 0 -0.3141247813967282 P46951 0.6779739856719971 1.0 43.350608634244175 45.0 1.0 no 4811 chrVII_895151r 14947 essential YGR198W 461 - TGTCTTGCGAAACTAGACCA D|160|H D|160|N YPP1 alpha-sYnuclein Protective Protein 817.0 0 0 0 0 -0.3930301752589124 P46951 0.15216892957687378 0.821226954460144 46.34080079957045 45.0 1.0 no 4812 chrVII_895458r 14951 essential YGR198W 768 - TCATTTGTCTCACTAGCAGT D|263|H D|263|N YPP1 alpha-sYnuclein Protective Protein 817.0 0 0 0 0 0.2556275591013836 P46951 0.01688552089035511 1.0 49.51981533901619 40.0 1.0 no 4813 chrVII_895646r 14953 essential YGR198W 956 - CGTCATTACTGTTATCGCTT D|325|H D|325|N YPP1 alpha-sYnuclein Protective Protein 817.0 0 1 0 0 -0.6401089248993047 P46951 47.42309934690877 40.0 1.0 no 4814 chrVII_895924 14954 essential YGR198W 1231 + GCCAATCAGAATCTTTAGAT Q|412|E Q|412|* S|411|R silent|AGC>AGT|S|411 YPP1 alpha-sYnuclein Protective Protein 817.0 0 0 0 0 -0.7714812878975355 P46951 1.0 0.4602460563182831 42.60588820673883 35.0 1.0 no 4815 chrVII_896278 14960 essential YGR198W 1585 + GGCATCTATTAGCTCTTTGT H|530|D H|530|Y L|531|V silent|CTA>TTA|L|531 YPP1 alpha-sYnuclein Protective Protein 817.0 0 0 0 0 -0.8230701706064205 P46951 0.0 0.0 0.0 50.44612795178591 40.0 1.0 no 4816 chrVII_896414 14962 essential YGR198W 1721 + TCACCTAAAATTAACGCAAT H|575|Q silent|CAC>CAT|H|575 H|575|D H|575|Y YPP1 alpha-sYnuclein Protective Protein 817.0 0 0 0 0 0.5781842998053964 P46951 0.9301652908325196 0.3184723556041717 0.1348305344581604 37.04681269749864 30.0 1.0 no 4817 chrVII_896517r 14966 essential YGR198W 1827 - TTCAATTCAGGTTGTGAATC L|615|F silent|TTG>TTA|L|615 YPP1 alpha-sYnuclein Protective Protein 817.0 0 0 0 0 -0.6082399418451659 P46951 0.7183715105056763 41.09165353936152 35.0 1.0 no 4818 chrVII_896526 14967 essential YGR198W 1833 + CAACCTGAATTGAACAGCAT P|613|A P|613|S P|613|R P|613|L YPP1 alpha-sYnuclein Protective Protein 817.0 0 0 0 0 0.8146586217195642 P46951 0.5190486311912537 0.4784835278987885 0.3368492126464844 0.1966252624988556 41.79812946756732 40.0 1.0 no 4819 chrVII_915271r 14969 essential YGR211W 33 - TCTGCAGCAGCTTCTCCTAC E|18|Q E|18|K A|17|P A|17|T ZPR1 Zinc finger PRotein 486.0 0 0 0 0 -1.6920459935803895 P53303 0.956179976463318 0.9475290179252625 0.9573720097541808 0.9523990154266356 0.5598164200782776 0.6615020036697388 0.16529110074043274 0.19367888569831848 58.255716290337936 55.00000000000001 1.0 no 4820 chrVII_915314r 14970 essential YGR211W 76 - GTCATTAGCTTTGTTCTGTT D|32|H D|32|N ZPR1 Zinc finger PRotein 486.0 0 0 0 0 0.5019706304515977 P53303 0.9486550092697144 0.956179976463318 0.17099010944366455 0.4991630911827088 48.66766820188195 35.0 1.0 no 4821 chrVII_915617r 14976 essential YGR211W 379 - TAGCTCGACAAACTTACAAG E|132|D silent|GAG>GAA|E|132 E|132|Q E|132|K ZPR1 Zinc finger PRotein 486.0 0 0 0 0 0.8503518712082454 P53303 0.94931298494339 0.956179976463318 0.9475290179252625 0.34912240505218506 0.20940367877483368 0.2081657201051712 2.0371999740600586 1.0784000158309937 1.0125999450683594 39.0388926768419 40.0 1.0 no 4822 chrVII_915664 14978 essential YGR211W 423 + GGTCAATTGACGACAGTTGA Q|143|E Q|143|* ZPR1 Zinc finger PRotein 486.0 0 1 0 0 -0.02007744831520697 P53303 0.9590039849281312 0.013668721541762352 45.07313757040862 45.0 1.0 no 4823 chrVII_915981r 14989 essential YGR211W 743 - CCAATTGTTTTAATTGTTCT L|254|F silent|TTG>TTA|L|254 ZPR1 Zinc finger PRotein 486.0 0 0 0 0 -0.22246218356980446 P53303 0.9587849974632264 0.4381990134716034 -0.006000000052154064 40.19222575253633 25.0 1.0 no 4824 chrVII_916080 14994 essential YGR211W 839 + CATCGAAAACTTTAACAACG I|281|M silent|ATC>ATT|I|281 ZPR1 Zinc finger PRotein 486.0 0 0 0 0 -0.2528266532342989 P53303 0.9598389863967896 0.11588578671216965 -0.3882000148296356 34.0983041970984 35.0 1.0 no 4825 chrVII_916313r 14997 essential YGR211W 1075 - CTCAGATTTCAAAATATCAC E|365|Q E|365|K ZPR1 Zinc finger PRotein 486.0 0 0 0 0 -0.7163878272684101 P53303 0.956179976463318 0.9475290179252625 0.01498163491487503 0.01161373034119606 35.29066757502767 30.0 1.0 no 4826 chrVII_923157 14999 essential YGR216C 1286 - TCCTCTTTTTACCGCAGAAC R|435|T R|435|K R|435|S silent|AGG>AGA|R|435 0 0 0 0 0.8206931189429476 P53306 0.932735025882721 0.955805003643036 0.9087679982185364 0.2645840346813202 1.0 0.2706364989280701 49.69228350475663 45.0 0.0 no 4827 chrVII_923266 15004 essential YGR216C 1177 - TGCAAAAAAATCAATCGCTA A|399|P A|399|T 0 0 0 0 1.0287434290982005 P53306 0.9573720097541808 0.9523990154266356 0.030841097235679626 0.5242988467216492 34.744535698983725 30.0 0.0 no 4828 chrVII_923444 15008 essential YGR216C 999 - GCATTTAATTTGATGCCAAG A|340|P A|340|T 0 0 0 0 0.9317879515542316 P53306 0.9573720097541808 0.9523990154266356 0.21152645349502566 0.38550680875778204 41.82852090976769 35.0 0.0 no 4829 chrVII_923913r 15015 essential YGR216C 527 + ATCTACTTGTATTTATAAAA S|177|C S|177|F T|178|S T|178|I 0 0 0 0 -2.6882809529546767 P53306 0.945252001285553 0.9294660091400146 0.9491789937019348 0.9472420215606691 0.19647471606731412 0.6669847369194031 0.4808911085128784 0.053072869777679436 31.128326162085386 15.0 0.0 yes 4830 chrVII_923941r 15016 essential YGR216C 499 + TGCTTAATAGTGTCGCAGCT L|168|V L|168|F 0 0 0 0 -0.003584447860852435 P53306 0.9512209892272948 0.9587849974632264 0.4432609081268311 0.8335589766502379 50.31073937111296 45.0 0.0 no 4831 chrVII_923982r 15018 essential YGR216C 458 + CCCGTTTATTCAAACATCAC P|154|R P|154|L P|154|A P|154|S 0 0 0 0 0.3816835031035097 P53306 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.011411462910473348 0.011083388701081276 0.08020758628845215 0.16615839302539825 44.64005107617425 40.0 0.0 no 4832 chrVII_924267r 15022 essential YGR216C 173 + TACTAAGAACAATGGAGCGG T|59|S T|59|I 0 0 0 0 0.6116116015240091 P53306 0.9491789937019348 0.9472420215606691 0.8353643417358398 0.44165554642677307 40.21060576816103 45.0 0.0 no 4833 chrVII_924419 15027 essential YGR216C 24 - TTCTCGAACAAGGATTCGTA E|14|D silent|GAG>GAA|E|14 E|14|Q E|14|K 0 0 0 0 0.7825075763130298 P53306 0.94931298494339 0.956179976463318 0.9475290179252625 0.4634368121623993 0.4322463870048523 0.836700975894928 42.636713606327596 40.0 0.0 no 4834 chrVII_932662 15029 essential YGR218W 121 + TTCAAGATAATCCAGACGCT Q|42|E Q|42|* CRM1 Chromosome Region Maintenance 1084.0 0 0 0 0 1.1555414161907287 P30822 0.9590039849281312 0.017844147980213162 1.8935999870300293 44.038526453560905 40.0 1.0 no 4835 chrVII_932673r 15030 essential YGR218W 135 - TCAGCTTTTTGCCAAGCGTC D|52|H D|52|N A|51|P A|51|T CRM1 Chromosome Region Maintenance 1084.0 0 1 0 0 0.6508485320165951 P30822 0.9486550092697144 0.956179976463318 0.9573720097541808 0.9523990154266356 0.11386469751596452 0.25471264123916626 0.00966600701212883 0.020904185250401497 53.98523868304841 50.0 1.0 no 4836 chrVII_932839r 15032 essential YGR218W 301 - TACTTCATCGTCTTGGCACA V|107|L V|107|I E|106|Q E|106|K CRM1 Chromosome Region Maintenance 1084.0 0 0 0 0 0.2259261718640679 P30822 0.9539830088615416 0.9574310183525084 0.956179976463318 0.9475290179252625 0.7559927105903625 0.4200903475284576 0.5724567174911499 0.8521313071250916 50.59086158167979 45.0 1.0 no 4837 chrVII_932909r 15034 essential YGR218W 371 - GCCATTCCTGCTTTAAAATT W|130|S W|130|* W|130|C W|130|* CRM1 Chromosome Region Maintenance 1084.0 0 0 0 0 0.26779549075922404 P30822 0.8858469724655151 0.8858469724655151 0.0 0.0 45.968698497322244 35.0 1.0 no 4838 chrVII_933152 15036 essential YGR218W 611 + TTCTTCAAGCTCTCTAATAG S|205|C S|205|F S|206|* S|206|L CRM1 Chromosome Region Maintenance 1084.0 0 0 0 0 -0.2124030475405871 P30822 0.945252001285553 0.9294660091400146 0.9298099875450134 0.06359129399061203 0.1059759184718132 0.07436452805995941 41.73879073323224 35.0 1.0 no 4839 chrVII_933699r 15045 essential YGR218W 1161 - CCGACTGATAACTGTATCAA G|394|R G|394|S V|393|L V|393|I CRM1 Chromosome Region Maintenance 1084.0 0 0 0 0 0.025115508947390786 P30822 0.941340982913971 0.951104998588562 0.9539830088615416 0.9574310183525084 0.593743622303009 0.9085240364074708 0.3773920834064484 0.2285522818565369 42.100325623317424 40.0 1.0 no 4840 chrVII_933751r 15047 essential YGR218W 1213 - TTTCATATATTCCGGATTTA M|410|I M|410|I CRM1 Chromosome Region Maintenance 1084.0 0 0 0 0 -0.25203575844604936 P30822 0.9553959965705872 0.9553959965705872 0.4679974913597107 0.4679974913597107 40.87273271205322 25.0 1.0 no 4841 chrVII_933863r 15049 essential YGR218W 1325 - CTTCATCATTTTCAACCACA E|448|Q E|448|K D|447|H D|447|N CRM1 Chromosome Region Maintenance 1084.0 0 0 0 0 0.5674469251267891 P30822 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.424413412809372 0.1872670203447342 0.003862858284264803 0.00783472415059805 44.80780553241488 35.0 1.0 no 4842 chrVII_934197 15054 essential YGR218W 1656 + TCGGATATTATGTACGTCGT S|553|W S|553|L CRM1 Chromosome Region Maintenance 1084.0 0 0 0 0 0.543576457689099 P30822 0.9288619756698608 0.9298099875450134 0.00035966112045571213 0.002281880471855402 45.08110662798122 40.0 1.0 no 4843 chrVII_934439 15058 essential YGR218W 1898 + TGCTGACCTACAGCCGCAAC A|634|G A|634|V D|635|E silent|GAC>GAT|D|635 CRM1 Chromosome Region Maintenance 1084.0 0 0 0 0 0.26744359468674617 P30822 0.9484469890594482 0.9504740238189696 0.9532920122146606 0.3800642490386963 0.322513222694397 0.009601770900189877 55.115229154053104 60.0 1.0 no 4844 chrVII_934588r 15061 essential YGR218W 2050 - CAACAATGTTGGGTTAGCAG L|689|F silent|TTG>TTA|L|689 CRM1 Chromosome Region Maintenance 1084.0 0 0 0 0 0.7940231606580794 P30822 0.9587849974632264 0.13395611941814425 44.139748397044 45.0 1.0 no 4845 chrVII_934683 15063 essential YGR218W 2142 + GCAGATTTCTATCCACAGTT A|715|G A|715|V CRM1 Chromosome Region Maintenance 1084.0 0 0 0 0 -0.11849215501006938 P30822 0.9484469890594482 0.9504740238189696 0.3764359056949616 0.2622066736221313 49.24551933702645 40.0 1.0 no 4846 chrVII_934864r 15064 essential YGR218W 2326 - ATCATCCAAATTTCTCGCCT D|782|H D|782|N D|781|H D|781|N CRM1 Chromosome Region Maintenance 1084.0 0 0 0 0 0.8022471415442345 P30822 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.6000341176986694 0.3466179966926575 0.09906034916639328 0.4397449195384979 49.21683926095165 40.0 1.0 no 4847 chrVII_934966r 15066 essential YGR218W 2428 - TGTCATACAATTTAGCACTT M|815|I M|815|I CRM1 Chromosome Region Maintenance 1084.0 0 0 0 0 0.3782532137317384 P30822 0.9553959965705872 0.9553959965705872 0.17360232770442965 0.17360232770442965 41.167198738398035 30.0 1.0 no 4848 chrVII_949814 15071 high_effect YGR229C 1066 - CACGTATTTCTGCTCCTGCA V|362|L V|362|M SMI1 Suppressor of MAR Inhibitor 505.0 0 1 0 0 0.24871654865372586 P32566 0.30882757902145386 0.10812990367412567 54.64123714304218 50.0 0.0 no 4849 chrVII_949828r 15072 high_effect YGR229C 1049 + TCAACCTGACACATCCTTGC Q|351|E Q|351|* P|352|A P|352|S SMI1 Suppressor of MAR Inhibitor 505.0 0 1 0 0 -0.02258547681058802 P32566 1.0 0.417926162481308 0.8806860446929932 51.19726002863911 50.0 0.0 no 4850 chrVII_949911 15073 high_effect YGR229C 969 - ACTTCGAAATAATCTTGTAT V|330|L V|330|I E|329|Q E|329|K SMI1 Suppressor of MAR Inhibitor 505.0 0 0 0 0 -0.5841339785445572 P32566 0.0 0.0 0.12549276649951935 0.11368024349212645 35.558374230917714 25.0 0.0 no 4851 chrVII_949974r 15074 high_effect YGR229C 903 + GACAATGACGACTACTTTAG D|302|E silent|GAC>GAT|D|302 SMI1 Suppressor of MAR Inhibitor 505.0 0 0 0 0 -0.5826313544148276 P32566 0.426257997751236 39.055165652576314 40.0 0.0 no 4852 chrVII_950209r 15087 high_effect YGR229C 668 + TCCTCCAAATGCAGTGCAAC P|224|R P|224|L P|224|A P|224|S SMI1 Suppressor of MAR Inhibitor 505.0 0 0 0 0 0.15234724196427515 P32566 0.0 0.0 0.0 0.0 50.123034969660075 50.0 0.0 no 4853 chrVII_950392 15091 high_effect YGR229C 488 - CCTGATCTAGTGTCATTAGT Q|169|H silent|CAG>CAA|Q|169 D|168|H D|168|N SMI1 Suppressor of MAR Inhibitor 505.0 0 0 0 0 -0.08284466620177666 P32566 0.011894693598151207 0.0 0.0 48.36793355643579 40.0 0.0 no 4854 chrVII_950466r 15092 high_effect YGR229C 411 + GCGTCTTTCAAAATTCATGA A|138|G A|138|V S|139|C S|139|F SMI1 Suppressor of MAR Inhibitor 505.0 0 0 0 0 0.9265851497668338 P32566 0.03136350214481354 0.16354107856750488 0.0 0.0 41.5642101871905 35.0 0.0 no 4855 chrVII_950562 15096 high_effect YGR229C 318 - CTCAAAGTTGCATTTAAATC L|112|F silent|TTG>TTA|L|112 SMI1 Suppressor of MAR Inhibitor 505.0 0 0 0 0 0.11381903285419133 P32566 0.12471607327461245 36.280498393747735 30.0 0.0 no 4856 chrVII_971816r 15107 high_effect YGR240C 1896 + TTCAGTGGATTGATTCAAAC F|633|L silent|TTC>TTT|F|633 PFK1 PhosphoFructoKinase 987.0 0 1 0 0 1.0292770041965569 P16861 0.9393529891967772 0.01227047760039568 2.1454000473022456 39.35947161006516 35.0 0.0 no 4857 chrVII_971867r 15111 high_effect YGR240C 1845 + ACTCTATACTGTTTGTCTCA L|617|V silent|CTA>TTA|L|617 T|616|S T|616|I PFK1 PhosphoFructoKinase 987.0 0 0 0 0 0.6751151895858104 P16861 0.9474369883537292 1.0095499753952026 1.0112500190734863 0.2603481709957123 0.007829908281564713 0.07771466672420503 1.3528000116348269 1.0886000394821167 -0.3856000006198883 46.2790598200021 35.0 0.0 no 4858 chrVII_971877 15112 high_effect YGR240C 1838 - AACAGTATAGAGTTGCGGCA C|619|S C|619|Y PFK1 PhosphoFructoKinase 987.0 0 0 0 0 0.025295548773205667 P16861 0.8039720058441162 0.5673800110816956 0.2204106152057648 0.007836805656552315 0.9236000180244446 11.07260036468506 47.31418164530476 45.0 0.0 no 4859 chrVII_971930r 15117 high_effect YGR240C 1782 + AACATTGGTATTGTCCATGT N|595|K silent|AAC>AAT|N|595 PFK1 PhosphoFructoKinase 987.0 0 1 0 0 0.07856629301205945 P16861 1.0071899890899658 0.8168835043907166 1.0371999740600586 45.530539615692184 35.0 0.0 no 4860 chrVII_971977 15118 high_effect YGR240C 1738 - TTCGGAACCATCATCTTTAA E|586|Q E|586|K PFK1 PhosphoFructoKinase 987.0 0 1 0 0 0.4509197753195802 P16861 1.0221500396728516 1.0125199556350708 0.6139789819717407 0.8967314958572388 0.10980000346899033 -0.3310000002384186 43.01826136420368 35.0 0.0 no 4861 chrVII_972104 15120 high_effect YGR240C 1611 - AACTTCACAGATTCAACCAA K|543|N silent|AAG>AAA|K|543 silent|GTG>GTC|V|542 silent|GTG>GTA|V|542 PFK1 PhosphoFructoKinase 987.0 0 1 0 0 0.6245288358796748 P16861 0.920903980731964 0.2079915553331375 0.3352000117301941 40.90604003424096 35.0 0.0 no 4862 chrVII_972198r 15122 high_effect YGR240C 1514 + ACAAGGTGTCGATGCTGTTA Q|506|E Q|506|* PFK1 PhosphoFructoKinase 987.0 0 0 0 0 -0.7241701562118016 P16861 0.6860269904136658 0.01269111968576908 2.4518001079559326 48.146631934643615 45.0 0.0 no 4863 chrVII_972262 15124 high_effect YGR240C 1453 - TCTTTGAACGTGACCTAGAA R|491|T R|491|K PFK1 PhosphoFructoKinase 987.0 0 0 0 0 -1.807544945883245 P16861 0.5878369808197021 0.6379320025444031 0.0 0.0 0.6805999875068665 0.6496000289916992 43.029203137364284 40.0 0.0 no 4864 chrVII_972368r 15127 high_effect YGR240C 1344 + AACACAATTATTGTCGCTGA N|449|K silent|AAC>AAT|N|449 T|450|R T|450|I PFK1 PhosphoFructoKinase 987.0 0 1 0 0 0.5406459161132938 P16861 0.9529910087585448 0.8197500109672546 0.985276997089386 0.021140385419130325 0.00289227650500834 1.0 4.678599834442139 0.5740000009536743 -2.2792000770568848 41.255310574605524 35.0 0.0 no 4865 chrVII_972437 15129 high_effect YGR240C 1278 - TCGTCCTGCCATTTTCCGTG E|433|Q E|433|K D|432|H D|432|N PFK1 PhosphoFructoKinase 987.0 0 1 0 0 -0.3321592721658342 P16861 1.0164999961853027 1.0043400526046753 0.936029016971588 0.956754982471466 0.4295641779899597 0.4213365912437439 0.013501442037522793 0.15211836993694305 0.3571999967098236 0.19740000367164606 0.3984000086784363 0.10620000213384627 58.28214386041748 55.00000000000001 0.0 no 4866 chrVII_972543 15132 high_effect YGR240C 1172 - TAACTTCAACAACAAAGGCA V|397|L V|397|I E|396|Q E|396|K PFK1 PhosphoFructoKinase 987.0 0 0 0 0 0.6015285571882468 P16861 0.6765900254249573 0.775967001914978 0.6809840202331543 0.6452640295028687 0.0 0.0 0.0 0.0 0.0130000002682209 1.3767999410629272 0.11479999870061874 -0.4839999973773956 37.58389524966333 35.0 0.0 no 4867 chrVII_972635r 15136 high_effect YGR240C 1077 + TCTGGTACTGACTCTACCAT S|360|C S|360|F PFK1 PhosphoFructoKinase 987.0 0 1 0 0 0.08894220415905688 P16861 0.8978220224380493 0.7245150208473206 0.21007640659809115 0.009653207845985891 0.5835999846458435 6.537199974060059 50.207563658526624 45.0 0.0 no 4868 chrVII_972686r 15137 high_effect YGR240C 1026 + TACAAGAATTTGTCCATTGT Y|343|* silent|TAC>TAT|Y|343 PFK1 PhosphoFructoKinase 987.0 0 0 0 0 0.7925871157023807 P16861 40.64897930717899 30.0 0.0 no 4869 chrVII_973136r 15144 high_effect YGR240C 576 + GACTTACTAAGACAAACATT D|193|E silent|GAC>GAT|D|193 L|195|V silent|CTA>TTA|L|195 PFK1 PhosphoFructoKinase 987.0 0 1 0 0 0.7089444474138318 P16861 1.020300030708313 1.0155099630355835 1.0 0.9100773334503174 35.180668866187766 30.0 0.0 no 4870 chrVII_973137r 15146 high_effect YGR240C 575 + TGACTTACTAAGACAAACAT D|193|E silent|GAC>GAT|D|193 PFK1 PhosphoFructoKinase 987.0 0 1 0 0 0.2794087475638433 P16861 1.020300030708313 1.0 35.0061227531304 30.0 0.0 no 4871 chrVII_973177 15147 high_effect YGR240C 538 - TCTAGAGATGATTTCGTCTT R|186|T R|186|K PFK1 PhosphoFructoKinase 987.0 0 1 0 0 0.6577165394246554 P16861 1.0033899545669556 1.0234600305557249 0.2199750542640686 1.0 43.4718097273954 35.0 0.0 no 4872 chrVII_973216 15149 high_effect YGR240C 499 - AGCATCTTTGGAAGTTGGAG A|173|P A|173|T D|172|H D|172|N PFK1 PhosphoFructoKinase 987.0 0 0 0 0 -0.6210615557070905 P16861 1.01774001121521 1.0170300006866455 0.9794660210609436 1.0084999799728394 0.34542596340179443 0.7061594128608704 0.09966077655553818 0.3987825512886048 46.236996896447295 45.0 0.0 no 4873 chrVII_973291 15151 high_effect YGR240C 424 - TTTCAAAAACACTAAGGTAT L|147|F silent|TTG>TTA|L|147 PFK1 PhosphoFructoKinase 987.0 0 1 0 0 0.5706593700809839 P16861 0.994211971759796 0.0907885953783989 33.23734799957674 25.0 0.0 no 4874 chrVII_973313 15152 high_effect YGR240C 402 - GACAATTTTTCGGCTTGTTT L|140|F silent|TTG>TTA|L|140 PFK1 PhosphoFructoKinase 987.0 0 1 0 0 -0.04696834294115332 P16861 1.016690015792847 0.6303997039794922 45.091259926278326 35.0 0.0 no 4875 chrVII_973314 15153 high_effect YGR240C 401 - ACAATTTTTCGGCTTGTTTT L|140|F silent|TTG>TTA|L|140 PFK1 PhosphoFructoKinase 987.0 0 1 0 0 0.19967400655053547 P16861 1.016690015792847 0.6303997039794922 44.145345286572244 30.0 0.0 no 4876 chrVII_973476 15155 high_effect YGR240C 239 - TAGCTTCTTGTTGTGGTATA A|86|P A|86|T E|85|Q E|85|K PFK1 PhosphoFructoKinase 987.0 0 1 0 0 0.26163132094742 P16861 0.9081990122795104 1.0082099437713623 0.964721977710724 0.9993000030517578 0.3409939408302307 0.6444121599197388 0.5817556381225586 0.9100729823112488 46.873045899867584 35.0 0.0 no 4877 chrVII_973543 15157 high_effect YGR240C 172 - AACTTCTCTCAAGGAATCTT V|64|L V|64|I E|63|Q E|63|K PFK1 PhosphoFructoKinase 987.0 0 0 0 0 -0.10538119063936953 P16861 1.0200400352478027 1.0250600576400757 0.8685610294342041 0.9542940258979796 41.776311360274356 35.0 0.0 no 4878 chrVII_973634r 15158 high_effect YGR240C 78 + ATTCACTTTTATCACACTCT H|28|D H|28|Y H|28|Q silent|CAC>CAT|H|28 PFK1 PhosphoFructoKinase 987.0 0 1 0 0 0.6409512632298928 P16861 1.034500002861023 0.9827929735183716 1.0390599966049194 0.847076952457428 0.04055118560791016 0.6401497721672058 43.32632787424457 30.0 0.0 no 4879 chrVII_980374 15162 essential YGR245C 1675 - ATCGACATCTACTTCCCAGT D|565|H D|565|N V|564|L V|564|I SDA1 Severe Depolymerization of Actin 767.0 0 0 0 0 -0.3978403109174706 P53313 0.9899479746818542 1.0004899501800537 0.9940739870071412 1.0010499954223633 0.013478362001478672 0.029975699260830883 0.3014551103115082 0.18632960319519046 51.76814625979324 45.0 0.0 no 4880 chrVII_980467 15164 essential YGR245C 1582 - AATCCCTTGAACACTGTTGT silent|GGG>GGC|G|533 silent|GGG>GGA|G|533 G|533|A G|533|E SDA1 Severe Depolymerization of Actin 767.0 0 0 0 0 -0.8065880485247334 P53313 0.9101750254631042 0.8975480198860168 0.21151115000247955 0.22879406809806824 47.37466415322791 40.0 0.0 no 4881 chrVII_980530 15167 essential YGR245C 1519 - GGCTTCTTGTACTTCCATGG A|513|P A|513|T E|512|Q E|512|K SDA1 Severe Depolymerization of Actin 767.0 0 0 0 0 -0.6168403185154085 P53313 0.920873999595642 0.912581980228424 0.934378981590271 0.9223290085792542 0.07044826447963715 0.2235596776008606 0.4528204798698425 0.7081598043441772 53.94574734264779 50.0 0.0 no 4882 chrVII_980602 15169 essential YGR245C 1447 - ATACAACGCTATCAATGACT L|488|F silent|TTG>TTA|L|488 silent|GCG>GCC|A|487 silent|GCG>GCA|A|487 SDA1 Severe Depolymerization of Actin 767.0 0 0 0 0 -0.0293131586375761 P53313 1.0031700134277344 0.0 40.07832297705022 35.0 0.0 no 4883 chrVII_980707 15170 essential YGR245C 1342 - ACGAGAGCATATTTCTCTAA R|454|P R|454|H SDA1 Severe Depolymerization of Actin 767.0 0 0 0 0 0.3486645715733756 P53313 0.960108995437622 1.0001100301742554 0.0 0.0 41.902141946278334 35.0 0.0 no 4884 chrVII_980799r 15173 essential YGR245C 1247 + TCCTGAAGTTATAAATGTCA P|417|R P|417|L P|417|A P|417|S SDA1 Severe Depolymerization of Actin 767.0 0 0 0 0 -1.7188619630004869 P53313 0.9753050208091736 0.9834169745445251 1.0002000331878662 0.9924110174179076 0.0 0.0 0.0 0.0 39.141466998724866 30.0 0.0 no 4885 chrVII_980942r 15177 essential YGR245C 1104 + CAGCTGTTATCAAGGTTGAT L|370|V silent|CTG>TTG|L|370 SDA1 Severe Depolymerization of Actin 767.0 0 0 0 0 -0.7608184456062519 P53313 0.9254159927368164 0.0 45.553157776993714 40.0 0.0 no 4886 chrVII_981121 15179 essential YGR245C 928 - CTTCTTCTTCACAGTTTTTA K|315|N silent|AAG>AAA|K|315 K|314|N silent|AAG>AAA|K|314 SDA1 Severe Depolymerization of Actin 767.0 0 1 0 0 0.4205374939316116 P53313 0.9018030166625975 0.9018030166625975 0.01085109356790781 0.1342305988073349 44.56304729845755 30.0 0.0 no 4887 chrVII_981214 15180 essential YGR245C 835 - ATCAAACCCATCCTCATCCT D|285|H D|285|N silent|GGG>GGC|G|283 silent|GGG>GGA|G|283 SDA1 Severe Depolymerization of Actin 767.0 0 0 0 0 -0.2288349285916437 P53313 0.9090110063552856 0.9202449917793274 0.0 0.0 52.97031461101585 45.0 0.0 no 4888 chrVII_981363r 15182 essential YGR245C 683 + ACTTTGGAGACGTGGTATTT L|229|V L|229|F SDA1 Severe Depolymerization of Actin 767.0 0 0 0 0 -1.1127164874397892 P53313 0.9950990080833436 1.0031700134277344 0.012141057290136814 0.011748573742806913 45.995946846037604 40.0 0.0 no 4889 chrVII_981682 15191 essential YGR245C 367 - TTCTTTCAATTCAAATGGCA E|129|Q E|129|K L|127|F silent|TTG>TTA|L|127 SDA1 Severe Depolymerization of Actin 767.0 0 0 0 0 0.4380506923044747 P53313 0.9209830164909364 0.9089339971542358 0.9229249954223632 0.05729011818766594 0.3183310627937317 0.029248280450701717 40.54634717771762 30.0 0.0 no 4890 chrVII_981798r 15193 essential YGR245C 248 + AACTTCGCAACTTATTGAAT T|84|S T|84|I S|85|W S|85|L SDA1 Severe Depolymerization of Actin 767.0 0 0 0 0 0.7843787281136242 P53313 0.9216309785842896 0.9196789860725404 0.8882390260696411 0.8951669931411743 0.8737765550613403 0.5875058174133301 0.016944469884037968 0.2934053540229797 38.32871513494069 30.0 0.0 no 4891 chrVII_981794r 15194 essential YGR245C 252 + TCGCAACTTATTGAATTGGT Q|86|E Q|86|* S|85|W S|85|L SDA1 Severe Depolymerization of Actin 767.0 0 0 0 0 -6.567760352304987 P53313 0.922443985939026 0.8882390260696411 0.8951669931411743 1.0 0.016944469884037968 0.2934053540229797 42.08300578296603 35.0 0.0 yes 4892 chrVII_981839r 15195 essential YGR245C 207 + TCTACAATGGCAGGTACTAA S|70|C S|70|F T|71|R T|71|I SDA1 Severe Depolymerization of Actin 767.0 0 0 0 0 0.6518038753931497 P53313 0.9879119992256165 0.9685909748077391 0.9773380160331726 0.9893620014190674 43.690442632971276 40.0 0.0 no 4893 chrVII_981939r 15199 essential YGR245C 107 + TGCACATTATGAATCGCTAA A|37|G A|37|V H|38|D H|38|Y SDA1 Severe Depolymerization of Actin 767.0 0 0 0 0 0.07761561552667656 P53313 0.9109870195388794 0.9102140069007874 0.9220200181007384 0.9221709966659546 0.5507314205169678 0.5799826979637146 0.1892268806695938 0.05854737013578415 41.1801561425645 35.0 0.0 no 4894 chrVII_981940r 15200 essential YGR245C 106 + ATGCACATTATGAATCGCTA A|37|G A|37|V H|38|D H|38|Y SDA1 Severe Depolymerization of Actin 767.0 0 0 0 0 0.2140526581765393 P53313 0.9109870195388794 0.9102140069007874 0.9220200181007384 0.9221709966659546 0.5507314205169678 0.5799826979637146 0.1892268806695938 0.05854737013578415 42.547855578822976 35.0 0.0 no 4895 chrVII_982974 15204 essential YGR246C 1279 - TTCTAGAGAGTAACCATCAA E|433|Q E|433|K BRF1 B-Related Factor 596.0 0 0 0 0 0.6032370304295993 P29056 0.956179976463318 0.9475290179252625 0.548064649105072 0.8400290012359619 41.132804389579746 35.0 0.0 no 4896 chrVII_983204 15208 essential YGR246C 1049 - CCTTAATCCTCTCCACAACA K|356|N silent|AAG>AAA|K|356 BRF1 B-Related Factor 596.0 0 0 0 0 -0.1131203093903068 P29056 0.9355990290641784 0.413997083902359 50.32739450859884 45.0 0.0 no 4897 chrVII_983290r 15210 essential YGR246C 960 + CCAATTTTGACGCAAGTATT P|321|R P|321|L BRF1 B-Related Factor 596.0 0 0 0 0 -1.1744724379383054 P29056 0.9432820081710817 0.9430609941482544 0.03992163017392159 0.047153227031230927 42.41584673313446 35.0 0.0 no 4898 chrVII_983385 15211 essential YGR246C 868 - TTTCTTTCTGTTCTTCACAA K|295|N silent|AAG>AAA|K|295 BRF1 B-Related Factor 596.0 0 0 0 0 0.6515965269012829 P29056 0.9355990290641784 0.25680238008499146 44.22613056258263 30.0 0.0 no 4899 chrVII_983580 15216 essential YGR246C 673 - AGCTAGTAGAATACATGCGC A|231|P A|231|T BRF1 B-Related Factor 596.0 0 0 0 0 -4.529458325053529 P29056 0.9573720097541808 0.9523990154266356 0.018223721534013748 0.017285998910665512 45.719083042140255 45.0 0.0 yes 4900 chrVII_983634r 15219 essential YGR246C 616 + CTCAAAGAATGTCCAAGGAC Q|207|E Q|207|* BRF1 B-Related Factor 596.0 0 0 0 0 0.14445549013482314 P29056 0.9590039849281312 0.5788738131523132 41.472805846024016 45.0 0.0 no 4901 chrVII_983744r 15221 essential YGR246C 506 + TATCACAGAATTGCCGTTAG I|170|M silent|ATC>ATT|I|170 T|171|R T|171|I BRF1 B-Related Factor 596.0 0 0 0 0 0.3839253392868522 P29056 0.9598389863967896 0.9476869702339172 0.9472420215606691 0.03804581239819527 0.014361288398504255 0.010999700985848905 43.77142930607636 40.0 0.0 no 4902 chrVII_983886 15225 essential YGR246C 367 - ACATGAAGCGATAACATTTT C|129|S C|129|Y BRF1 B-Related Factor 596.0 0 0 0 0 0.2566950333102121 P29056 0.9421560168266296 0.9290120005607604 0.0 0.0 37.825188744455254 30.0 0.0 no 4903 chrVII_983936 15227 essential YGR246C 317 - CCAATGCAAGCTTATACCAT L|112|F silent|TTG>TTA|L|112 A|111|P A|111|T BRF1 B-Related Factor 596.0 0 0 0 0 -0.11839224451170792 P29056 0.9587849974632264 0.9573720097541808 0.9523990154266356 0.026755966246128082 0.030948031693696976 0.02879672311246395 46.431143799721546 40.0 0.0 no 4904 chrVII_983963 15228 essential YGR246C 290 - CAGCATCTGTGATATATTCC A|103|P A|103|T D|102|H D|102|N BRF1 B-Related Factor 596.0 0 0 0 0 -0.5877635478341633 P29056 0.9573720097541808 0.9523990154266356 0.9486550092697144 0.956179976463318 0.104366235435009 0.4886208772659302 0.011353079229593277 0.02652835659682751 46.11788889956671 40.0 0.0 no 4905 chrVII_983981r 15229 essential YGR246C 269 + TTCTTACGCATTACATATCC S|91|C S|91|F Y|92|* silent|TAC>TAT|Y|92 BRF1 B-Related Factor 596.0 0 0 0 0 -1.3167227826533057 P29056 0.945252001285553 0.9294660091400146 0.011026664637029173 0.004609173163771629 44.375297865112884 35.0 0.0 no 4906 chrVII_984070r 15230 essential YGR246C 180 + GGACAAAGTCATGCTGCATT Q|62|E Q|62|* BRF1 B-Related Factor 596.0 0 0 0 0 0.8313058192103413 P29056 0.9590039849281312 0.0 47.089362282763204 45.0 0.0 no 4907 chrVII_984201 15234 essential YGR246C 52 - AACTAAATCGTTGTTAGCAT V|24|L V|24|I BRF1 B-Related Factor 596.0 0 1 0 0 -0.1734739927250542 P29056 0.9539830088615416 0.9574310183525084 0.22330784797668454 0.4501304626464844 38.85178191137186 30.0 0.0 no 4908 chrVII_995704 15236 essential YGR251W 65 + TAACAATACTGCTGCAGTTT N|23|K silent|AAC>AAT|N|23 NOP19 NucleOlar Protein 196.0 0 0 0 0 0.9098372817153816 P53317 0.9117769598960876 42.64685631616555 35.0 1.0 no 4909 chrVII_995831 15238 essential YGR251W 192 + AAGCTTCCCGTTTTGCAGAT L|66|V L|66|F P|67|A P|67|S NOP19 NucleOlar Protein 196.0 0 0 0 0 -0.007483308242901694 P53317 0.0 0.0 0.0 0.0 52.74594158839807 45.0 1.0 no 4910 chrVII_995985 15243 essential YGR251W 346 + TGCAACGAAATAATATGTAC Q|117|E Q|117|* R|118|G R|118|* NOP19 NucleOlar Protein 196.0 0 0 0 0 -1.020517570066822 P53317 1.0 0.3602352738380432 33.62388977829869 30.0 1.0 no 4911 chrVII_997136r 15251 high_effect YGR252W 270 - TCATTTTCCTCTACGACACT E|97|Q E|97|K GCN5 General Control Nonderepressible 439.0 0 0 0 0 -0.406245060348839 Q03330 0.956179976463318 0.9475290179252625 0.6200488805770874 0.9594432711601256 48.114018954948556 40.0 1.0 no 4912 chrVII_997137r 15252 high_effect YGR252W 271 - TTCATTTTCCTCTACGACAC E|97|Q E|97|K GCN5 General Control Nonderepressible 439.0 0 0 0 0 0.2235307301680929 Q03330 0.956179976463318 0.9475290179252625 0.6200488805770874 0.9594432711601256 46.56286377186024 40.0 1.0 no 4913 chrVII_997263r 15254 high_effect YGR252W 397 - TAACCTGGCAATGTATTCTT R|138|S silent|AGG>AGA|R|138 R|138|T R|138|K GCN5 General Control Nonderepressible 439.0 0 0 0 0 -0.8791540307182876 Q03330 0.9087679982185364 0.932735025882721 0.955805003643036 0.002110424218699336 0.0026484637055546045 0.051444988697767265 0.4388599991798401 1.0080800056457522 -0.2467000037431717 44.380863690586516 35.0 1.0 no 4914 chrVII_997302 15255 high_effect YGR252W 433 + ATCTTTCCATGGCTGTCATT L|146|V L|146|F S|147|C S|147|F GCN5 General Control Nonderepressible 439.0 0 0 0 0 0.21176911329546955 Q03330 0.9512209892272948 0.9587849974632264 0.945252001285553 0.9294660091400146 0.5013396143913269 0.7013927102088928 0.13098342716693878 0.009015179239213468 1.5545200109481812 -0.24167999625205994 -0.4374000132083893 14.981088638305664 52.04499893835128 40.0 1.0 no 4915 chrVII_997308r 15256 high_effect YGR252W 442 - TGGCTTCCTAATGACAGCCA K|153|N silent|AAG>AAA|K|153 R|152|S silent|AGG>AGA|R|152 GCN5 General Control Nonderepressible 439.0 0 0 0 0 -0.7193058566946308 Q03330 0.9355990290641784 0.9087679982185364 0.04780328646302223 0.004116872791200875 0.21673999726772308 2.5877599716186523 53.530367465250386 50.0 1.0 no 4916 chrVII_997328r 15257 high_effect YGR252W 462 - ATGCCACCTACGACAGTCAA G|160|A G|160|D G|160|R G|160|S GCN5 General Control Nonderepressible 439.0 0 0 0 0 -0.27612309353508857 Q03330 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.0 0.0 0.0 0.0 6.904652118682861 22.19642448425293 30.44239997863769 12.633813858032227 51.17652459527295 50.0 1.0 no 4917 chrVII_997393 15259 high_effect YGR252W 524 + TTTCTGTGCCATCAGTTCGA F|176|L silent|TTC>TTT|F|176 GCN5 General Control Nonderepressible 439.0 0 0 0 0 1.1308367375267303 Q03330 0.9387490153312684 0.0 1.4469200372695925 52.786494210081635 45.0 1.0 no 4918 chrVII_997687r 15261 high_effect YGR252W 821 - TCGTTCTTATTTTTCTTCGC silent|ACG>ACC|T|280 silent|ACG>ACA|T|280 R|279|T R|279|K GCN5 General Control Nonderepressible 439.0 0 0 0 0 0.9535434359464364 Q03330 0.932735025882721 0.955805003643036 0.009318229742348194 0.5285149216651917 46.805775596015785 35.0 1.0 no 4919 chrVII_997733r 15263 high_effect YGR252W 867 - TCTTTGAATTGCTCTAAACC D|296|H D|296|N GCN5 General Control Nonderepressible 439.0 0 0 0 0 -0.4549486987830647 Q03330 0.9486550092697144 0.956179976463318 0.07132074981927873 0.6962499022483826 41.55644514527978 35.0 1.0 no 4920 chrVII_997781r 15264 high_effect YGR252W 915 - TTCAAGCCAGGAATAGTCAT L|311|F silent|TTG>TTA|L|311 G|310|A G|310|D GCN5 General Control Nonderepressible 439.0 0 0 0 0 -1.24082737725376 Q03330 0.9587849974632264 0.9499930143356324 0.9446240067481996 0.009110906161367891 0.2270334213972092 0.00216781347990036 45.60447674213481 40.0 1.0 no 4921 chrVII_998607 15269 essential YGR253C 514 - TCCTTCAGAGCCTGAACCAA G|178|R G|178|R G|178|A G|178|E PUP2 PUtative Proteasome subunit 260.0 0 0 0 0 -0.1869384892611567 P32379 0.9334250092506408 0.9334250092506408 0.9504340291023254 0.9366250038146972 0.05492783337831497 0.05492783337831497 0.2541066408157349 0.1860361099243164 -1.3387199640274048 -1.3387199640274048 -0.8505200147628784 -0.7080640196800232 0.5917999744415283 0.5917999744415283 -0.06679999828338623 0.2003999948501587 52.4766074351042 50.0 0.0 no 4922 chrVII_998641 15271 essential YGR253C 480 - TAACGGTAAAATGTCCCAGA R|166|P R|166|H PUP2 PUtative Proteasome subunit 260.0 0 1 0 0 -0.3098238792105199 P32379 0.9226930141448976 0.963467001914978 0.0974223166704178 0.04323868080973625 0.061514001339674 0.6246860027313232 0.07970000803470613 1.0216699838638306 42.62760908225465 40.0 0.0 no 4923 chrVII_998723r 15273 essential YGR253C 395 + ACTAATGTCTCGACCATTCG L|133|V silent|CTA>TTA|L|133 PUP2 PUtative Proteasome subunit 260.0 0 1 0 0 -0.5429613869635508 P32379 0.9703750014305116 0.3441812098026276 0.28871798515319824 0.05302000045776367 0.36039999127388 46.14677722587965 45.0 0.0 no 4924 chrVII_998787 15275 essential YGR253C 334 - ATCACACACCGATTGCGTTA D|118|H D|118|N C|117|S C|117|Y PUP2 PUtative Proteasome subunit 260.0 0 0 0 0 0.5336784868642945 P32379 0.965224027633667 0.97645902633667 0.9445559978485109 0.9245190024375916 0.009445800445973871 0.32413530349731445 0.6525237560272217 0.0047891540452837935 0.2639099955558777 -0.15144799649715426 1.032014012336731 17.287982940673828 0.7807999849319458 14.629779815673828 -0.008275002241134644 -0.20247000455856326 1.0943000316619873 16.81962013244629 48.84061685208076 45.0 0.0 no 4925 chrVII_999030 15277 essential YGR253C 91 - TGCTGTAGATCCTAATTTGA A|37|P A|37|T PUP2 PUtative Proteasome subunit 260.0 0 1 0 0 0.32275927697004675 P32379 0.9527850151062012 0.9463250041007996 0.010117042809724808 0.2668790817260742 8.192939758300781 -0.3729360103607178 44.212313456980105 35.0 0.0 no 4926 chrVII_999056r 15280 essential YGR253C 62 + ATTCCAAGTTGAGTATTCTT F|22|L silent|TTC>TTT|F|22 Q|23|E Q|23|* PUP2 PUtative Proteasome subunit 260.0 0 0 0 0 -0.5369288158382846 P32379 0.9483659863471984 1.0026899576187134 0.4016789793968201 0.006502117495983839 0.5330359935760498 -0.2185979932546616 0.4169400036334992 1.3035600185394287 1.368399977684021 43.437166859392335 30.0 0.0 no 4927 chrVII_999070 15281 essential YGR253C 51 - ACTTGGAATAACCTCCCTTC V|24|L V|24|I PUP2 PUtative Proteasome subunit 260.0 0 0 0 0 0.3674373637618478 P32379 0.9769399762153624 0.9846090078353882 0.007183825131505728 0.009899129159748554 -0.8110979795455933 -1.0452599525451658 -0.8273599743843079 -1.0883599519729614 0.36212000250816345 1.0928733348846436 49.367335432685366 45.0 0.0 no 4928 chrVII_1017206 15288 high_effect YGR262C 534 - AGACCGAAATCAATCAAATG G|184|A G|184|D G|184|R G|184|S BUD32 BUD site selection 261.0 0 0 0 0 -0.8751691899228811 P53323 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.0 0.0 0.0 0.0 -0.4186800122261048 0.6990799903869629 -0.5073999762535095 -0.5543199777603149 35.63374652695671 35.0 0.0 no 4929 chrVII_1017297 15291 high_effect YGR262C 443 - TCCAGTGCAACAACCCAATT W|154|S W|154|* W|154|C W|154|* BUD32 BUD site selection 261.0 0 0 0 0 -1.1417516373757068 P53323 0.8858469724655151 0.8858469724655151 0.8203386664390564 0.121639184653759 2.7557199001312256 2.358099937438965 49.3526831561835 45.0 0.0 no 4930 chrVII_1017281r 15292 high_effect YGR262C 456 + CACTGGAATGACTACTGTCA H|153|Q silent|CAC>CAT|H|153 BUD32 BUD site selection 261.0 0 0 0 0 -0.2526286568081183 P53323 0.9588389992713928 0.0 1.6099799871444702 44.87730221464505 45.0 0.0 no 4931 chrVII_1017323r 15295 high_effect YGR262C 414 + GCAACTACACTACGGAAAGT A|139|G A|139|V T|140|S T|140|I BUD32 BUD site selection 261.0 0 0 0 0 -1.7397359432744763 P53323 0.9484469890594482 0.9504740238189696 0.9491789937019348 0.9472420215606691 0.4033767580986023 0.3592990040779114 0.7304550409317017 0.18811944127082825 1.0262000560760498 -0.03313999995589256 -0.17655999958515167 -0.7929800152778625 42.818904651668724 45.0 0.0 no 4932 chrVII_1017331r 15296 high_effect YGR262C 406 + ATCTTGTAGCAACTACACTA L|137|V L|137|F BUD32 BUD site selection 261.0 0 0 0 0 0.6618395752341361 P53323 0.9512209892272948 0.9587849974632264 0.2616923451423645 0.04622698202729225 1.3905800580978394 1.2953599691390991 42.89239303342959 35.0 0.0 no 4933 chrVII_1017465 15300 high_effect YGR262C 275 - GATCACACGCTATCAGTTGA D|98|H D|98|N C|97|S C|97|Y BUD32 BUD site selection 261.0 0 0 0 0 0.0653173915435937 P53323 0.9486550092697144 0.956179976463318 0.9421560168266296 0.9290120005607604 0.0 0.0 0.1864684671163559 0.15707357227802274 2.3769400119781494 1.2767599821090698 1.2353999614715576 0.4218400120735169 47.469891875808905 45.0 0.0 no 4934 chrVII_1017496r 15301 high_effect YGR262C 241 + CCAAATTATACTTGATTCCA silent|GCC>GCG|A|81 silent|GCC>GCT|A|81 BUD32 BUD site selection 261.0 0 0 0 0 0.6389269351096407 P53323 40.881759955728505 30.0 0.0 no 4935 chrVII_1020438 15311 essential YGR264C 1396 - CCACCATTGTTTCCATTCTT W|471|C W|471|* W|472|S W|472|* MES1 MEthionyl-tRNA Synthetase 751.0 0 0 0 0 -2.383343675459027 P00958 0.7836369872093201 0.7959150075912476 0.0005103986477479339 0.002556701423600316 52.72498394727063 40.0 0.0 yes 4936 chrVII_1020447 15312 essential YGR264C 1387 - TTTCCATTCTTTGGTGTAGT W|468|C W|468|* W|468|S W|468|* MES1 MEthionyl-tRNA Synthetase 751.0 0 0 0 0 0.1438955088604828 P00958 0.7853369712829591 0.8391590118408203 0.0006597759784199297 0.0010958830825984476 49.39234333091389 35.0 0.0 no 4937 chrVII_1020869r 15320 essential YGR264C 962 + TCCAGTTCATAATTCTTATC P|322|R P|322|L P|322|A P|322|S MES1 MEthionyl-tRNA Synthetase 751.0 0 0 0 0 0.12488226414634372 P00958 0.9411640167236328 0.9969499707221984 1.0185099840164185 1.0077999830245972 0.15265490114688873 0.08795289695262909 0.23851557075977325 0.23150499165058136 42.03258075423275 30.0 0.0 no 4938 chrVII_1021020r 15321 essential YGR264C 811 + TCCACAGTGACGTTTACAAG H|272|D H|272|Y I|271|M silent|ATC>ATT|I|271 MES1 MEthionyl-tRNA Synthetase 751.0 0 1 0 0 -2.658360052383061 P00958 0.8447369933128357 0.8453490138053894 0.8680869936943054 0.0 0.0 0.012564236298203468 45.36993391028914 45.0 0.0 yes 4939 chrVII_1021019 15322 essential YGR264C 815 - ACCACTTGTAAACGTCACTG W|278|S W|278|* W|278|C W|278|* MES1 MEthionyl-tRNA Synthetase 751.0 0 1 0 0 -0.9381408015227412 P00958 0.8041380047798157 0.7861989736557007 0.0006507031503133477 0.000546925060916692 45.01217553756277 45.0 0.0 no 4940 chrVII_1021122 15324 essential YGR264C 712 - ATCAGTACCACAAATAAACA D|244|H D|244|N MES1 MEthionyl-tRNA Synthetase 751.0 0 0 0 0 -6.181017358410681 P00958 0.8330860137939453 0.8595960140228271 0.0016361959278583527 0.005201566033065319 36.76475708886011 30.0 0.0 yes 4941 chrVII_1021213r 15326 essential YGR264C 618 + GTCAACAACGTTCCACACTT silent|GTC>GTG|V|207 silent|GTC>GTT|V|207 N|208|K silent|AAC>AAT|N|208 MES1 MEthionyl-tRNA Synthetase 751.0 0 0 0 0 -2.0390347550011034 P00958 0.8486019968986511 0.0 47.51673617076494 45.0 0.0 yes 4942 chrVII_1025272r 15345 essential YGR267C 441 + ATACCAAATAAAAAAGTCAT P|149|A P|149|S P|149|R P|149|L FOL2 FOLic acid synthesis 243.0 0 0 0 0 -1.319891840451002 P51601 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.0 0.0 0.0 0.0 30.222196585121765 20.0 0.0 no 4943 chrVII_1025314r 15346 essential YGR267C 399 + CATCATTTGGTGCCATTTTT H|135|D H|135|Y FOL2 FOLic acid synthesis 243.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.7689194370574619 P51601 0.9473130106925964 0.9489949941635132 0.0 0.0 0.09130000323057176 -0.5430600047111511 0.1599999964237213 -1.565600037574768 48.16831948230094 35.0 0.0 no 4944 chrVII_1025702 15353 essential YGR267C 14 - TTTCTATCTCTTGCACTAAT E|11|Q E|11|K FOL2 FOLic acid synthesis 243.0 0 1 0 0 0.21821918737889784 P51601 0.956179976463318 0.9475290179252625 0.3381794393062592 0.4587681293487549 42.929433048361204 30.0 0.0 no 4945 chrVII_1040794 15354 essential YGR274C 2282 - CCTGACTCATTGATTCAACT Q|767|H silent|CAG>CAA|Q|767 S|766|T S|766|N TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 -1.345598564024154 P46677 0.9570760130882264 0.9512869715690612 0.9536849856376648 0.2153359055519104 0.5292611718177795 0.8756164312362671 -0.5767999887466431 0.734000027179718 -0.9132000207901 45.39863188621485 40.0 0.0 no 4946 chrVII_1040808 15356 essential YGR274C 2268 - TCAACTTGGCTGATCTGCTC E|763|Q E|763|K V|762|L V|762|I TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 -0.5908224983816102 P46677 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.027429496869444847 0.021685102954506874 1.0 0.2439333349466324 -0.2696000039577484 0.32499998807907104 0.01720000058412552 0.07980000227689743 51.13230876018167 50.0 0.0 no 4947 chrVII_1040966 15359 essential YGR274C 2110 - GTCGGGAAAGTGCTTTGCAA D|710|H D|710|N TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 0.3460395173464141 P46677 0.9486550092697144 0.956179976463318 0.02353413961827755 0.12223672866821288 0.13379999995231628 0.1298000067472458 48.784468577730415 50.0 0.0 no 4948 chrVII_1040944 15360 essential YGR274C 2132 - GTCTGTTTTGTCCATAATCT R|717|T R|717|K TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 0.4674578325043287 P46677 0.932735025882721 0.955805003643036 0.0 0.0 -0.11640000343322755 -0.125 47.441303554137725 35.0 0.0 no 4949 chrVII_1040955r 15361 essential YGR274C 2118 + CACTTTCCCGACCAAGATTA H|707|Q silent|CAC>CAT|H|707 P|709|A P|709|S TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 0.4308219046632645 P46677 0.9588389992713928 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.5266000032424927 0.8658000230789185 1.4794000387191772 0.2482600063085556 2.1940600872039795 2.509200096130371 49.07951634445907 45.0 0.0 no 4950 chrVII_1041177r 15367 essential YGR274C 1896 + TTTCTTCTGACAAAAAGTTC L|634|V L|634|F L|635|V silent|CTG>TTG|L|635 TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 0.6749434665289571 P46677 0.9512209892272948 0.9587849974632264 0.9512209892272948 0.0 0.0 0.15198630094528198 1.975600004196167 0.8518000245094299 1.008999943733215 2.0053200721740723 4.0575599670410165 1.6198400259017944 36.38492406501757 30.0 0.0 no 4951 chrVII_1041241 15368 essential YGR274C 1835 - TCATGTTATTGTATAATGTG M|618|I M|618|I TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 0.35412569182969755 P46677 0.9553959965705872 0.9553959965705872 0.04658322408795357 0.04658322408795357 2.338200092315674 2.338200092315674 36.079078830368815 25.0 0.0 no 4952 chrVII_1041282 15370 essential YGR274C 1794 - ACAAATCCAAAGTTCCAAAA V|605|L V|605|I G|603|A G|603|E TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 0.036852261247054346 P46677 0.9539830088615416 0.9574310183525084 0.9499930143356324 0.9438679814338684 0.0 0.0 0.0 0.0 2.58240008354187 -0.7310000061988831 4.493400096893311 15.321399688720705 36.725767891747296 30.0 0.0 no 4953 chrVII_1041296r 15371 essential YGR274C 1777 + TTCAAGACAAATCACCATTT Q|594|E Q|594|* TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 0.3173504158036973 P46677 0.9590039849281312 0.048913929611444466 -0.07739999890327454 39.0244340423817 30.0 0.0 no 4954 chrVII_1041356r 15372 essential YGR274C 1717 + CCAATGAACAAGATACTCTA silent|GCC>GCG|A|573 silent|GCC>GCT|A|573 TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 0.5151018312760903 P46677 38.48119216992427 35.0 0.0 no 4955 chrVII_1041409r 15373 essential YGR274C 1664 + AGCTTTGTCTAAATTTGGTA A|556|G A|556|V TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 0.9580880531765724 P46677 0.9484469890594482 0.9504740238189696 0.053055793046951294 1.0 1.2510000467300415 -0.7563999891281128 41.77542006872972 30.0 0.0 no 4956 chrVII_1041454r 15375 essential YGR274C 1619 + TACTGCTCCTGTTTATTTAA T|541|S T|541|I A|542|G A|542|V TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 0.24797540898686604 P46677 0.9491789937019348 0.9472420215606691 0.9484469890594482 0.9504740238189696 1.0 0.008979236707091331 0.15186139941215515 0.014908991754055025 0.12139999866485594 0.2804000079631805 0.9290000200271606 0.5892000198364258 1.5438599586486816 -1.258020043373108 43.96921257308526 30.0 0.0 no 4957 chrVII_1041478r 15377 essential YGR274C 1595 + ATCTCAAGATCTAACCATCG S|533|C S|533|F Q|534|E Q|534|* TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 -0.9156546847977016 P46677 0.945252001285553 0.9294660091400146 0.9590039849281312 0.009722895920276642 0.005042825359851122 1.0 -1.0363999605178833 0.6863999962806702 0.12999999523162842 0.521340012550354 10.275659561157227 0.3317799866199493 42.686371838191796 40.0 0.0 no 4958 chrVII_1041479r 15378 essential YGR274C 1594 + CATCTCAAGATCTAACCATC S|533|C S|533|F Q|534|E Q|534|* TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 -0.6019276051419044 P46677 0.945252001285553 0.9294660091400146 0.9590039849281312 0.009722895920276642 0.005042825359851122 1.0 -1.0363999605178833 0.6863999962806702 0.12999999523162842 0.521340012550354 10.275659561157227 0.3317799866199493 42.69838768418549 40.0 0.0 no 4959 chrVII_1041480r 15379 essential YGR274C 1593 + ACATCTCAAGATCTAACCAT T|532|R T|532|I S|533|C S|533|F TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 0.6541470113172707 P46677 0.9476869702339172 0.9472420215606691 0.945252001285553 0.9294660091400146 0.4578651785850525 0.0657910704612732 0.009722895920276642 0.005042825359851122 -0.9860000014305116 0.08860000222921371 -1.0363999605178833 0.6863999962806702 -2.2070798873901367 -0.8292999863624573 0.521340012550354 10.275659561157227 42.20066158589282 35.0 0.0 no 4960 chrVII_1041788 15382 essential YGR274C 1288 - TTGCAAAATAGTTTCGTTGA L|435|F silent|TTG>TTA|L|435 TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 0.6421481120716851 P46677 0.9587849974632264 0.27985432744026184 38.875912413349965 30.0 0.0 no 4961 chrVII_1041789 15383 essential YGR274C 1287 - TGCAAAATAGTTTCGTTGAG L|435|F silent|TTG>TTA|L|435 TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 0.8110442145965742 P46677 0.9587849974632264 0.27985432744026184 38.66095219073037 35.0 0.0 no 4962 chrVII_1041992 15384 essential YGR274C 1084 - GCTCTTCAATTTATAACCGC K|367|N silent|AAG>AAA|K|367 S|368|T S|368|N TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 0.0658980530035806 P46677 0.9355990290641784 0.9512869715690612 0.9536849856376648 0.5575931668281555 0.5564955472946167 0.8441801071166992 45.55128610602145 40.0 0.0 no 4963 chrVII_1042045r 15388 essential YGR274C 1028 + TTCATCAACAGCAACCTTGG S|344|* S|344|L S|345|* S|345|L TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 -0.32026603761886085 P46677 0.9298099875450134 0.9298099875450134 0.06187413632869721 0.3116205334663391 46.513075750826424 45.0 0.0 no 4964 chrVII_1042031 15390 essential YGR274C 1045 - TGTCATAGACGAATCCGCCA M|354|I M|354|I TAF1 TATA binding protein-Associated Factor 1066.0 0 1 0 0 1.0299289915553769 P46677 0.9553959965705872 0.9553959965705872 0.2467202842235565 0.2467202842235565 50.472449039950114 50.0 0.0 no 4965 chrVII_1042048r 15391 essential YGR274C 1025 + TACTTCATCAACAGCAACCT T|343|S T|343|I S|344|* S|344|L TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 -0.4561101494181924 P46677 0.9491789937019348 0.9472420215606691 0.9298099875450134 0.6896649599075317 0.15697605907917025 0.06187413632869721 45.61028348611944 40.0 0.0 no 4966 chrVII_1042097r 15393 essential YGR274C 976 + TGCTTATTGCCACTGATGAT L|327|V L|327|F TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 -0.259134753393564 P46677 0.9512209892272948 0.9587849974632264 0.76927649974823 0.7073816657066345 48.09464117977768 40.0 0.0 no 4967 chrVII_1042202 15395 essential YGR274C 874 - AACATGAATTAAACCTCTTC V|298|L V|298|I TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 0.06233207242261692 P46677 0.9539830088615416 0.9574310183525084 0.3908003270626068 1.0 -0.477180004119873 -0.2655200064182281 36.57541463628058 30.0 0.0 no 4968 chrVII_1042201 15396 essential YGR274C 875 - AAACATGAATTAAACCTCTT V|298|L V|298|I TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 0.38528296584686383 P46677 0.9539830088615416 0.9574310183525084 0.3908003270626068 1.0 -0.477180004119873 -0.2655200064182281 34.661078508038266 25.0 0.0 no 4969 chrVII_1042215r 15397 essential YGR274C 858 + AACTCTTCTGCATCCCGAAG N|287|K silent|AAC>AAT|N|287 S|288|C S|288|F TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 -1.5327929297232066 P46677 0.9439849853515624 0.945252001285553 0.9294660091400146 0.9322391152381896 0.07279615104198456 0.11545995622873305 50.130274383078756 50.0 0.0 no 4970 chrVII_1042259r 15398 essential YGR274C 814 + ACGTCGCTCCGATTTATCAA Y|272|* silent|TAC>TAT|Y|272 silent|GTC>GTG|V|273 silent|GTC>GTT|V|273 TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 1.0316516109532703 P46677 48.76136090992589 45.0 0.0 no 4971 chrVII_1042260r 15399 essential YGR274C 813 + TACGTCGCTCCGATTTATCA Y|272|* silent|TAC>TAT|Y|272 silent|GTC>GTG|V|273 silent|GTC>GTT|V|273 TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 -0.40296949876727145 P46677 49.78127772443202 45.0 0.0 no 4972 chrVII_1042335 15400 essential YGR274C 741 - TTCAAATTTAAAGGCATAAA L|253|F silent|TTG>TTA|L|253 TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 0.1987458783754392 P46677 0.9587849974632264 0.05280809849500656 31.09610296383164 20.0 0.0 no 4973 chrVII_1042518 15401 essential YGR274C 558 - TGCTTGCCATCTGACATATC K|192|N silent|AAG>AAA|K|192 G|191|A G|191|D TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 0.42176914585081227 P46677 0.9355990290641784 0.9499930143356324 0.9446240067481996 0.4089198112487793 0.7525136470794678 0.6191587448120117 50.06304872308334 45.0 0.0 no 4974 chrVII_1042590r 15402 essential YGR274C 483 + GGGCATTCTCAACTTTCCAT H|163|D H|163|Y TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 -0.12951919086427405 P46677 0.9473130106925964 0.9489949941635132 0.5832245349884033 1.0 51.85695838699371 45.0 0.0 no 4975 chrVII_1042683r 15403 essential YGR274C 390 + ACTAGCAATGCTTTGTTTAT T|131|S T|131|I S|132|R silent|AGC>AGT|S|132 TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 -0.4345487075204793 P46677 0.9491789937019348 0.9472420215606691 0.9417110085487366 0.7891439199447632 0.18887296319007876 0.3255073726177216 42.859958254461105 30.0 0.0 no 4976 chrVII_1042684r 15404 essential YGR274C 389 + AACTAGCAATGCTTTGTTTA T|131|S T|131|I S|132|R silent|AGC>AGT|S|132 TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 0.9429899301499466 P46677 0.9491789937019348 0.9472420215606691 0.9417110085487366 0.7891439199447632 0.18887296319007876 0.3255073726177216 41.38072817081871 30.0 0.0 no 4977 chrVII_1042746 15407 essential YGR274C 330 - GACAAATCACCATTAATTTC L|116|F silent|TTG>TTA|L|116 TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 0.035459543863989564 P46677 0.9587849974632264 0.7227304577827454 37.198524531426585 30.0 0.0 no 4978 chrVII_1042839r 15410 essential YGR274C 234 + CATCCAGCTATGATGACTAT P|80|A P|80|S P|80|R P|80|L TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 0.4879291711944463 P46677 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.39711734652519226 0.4418053328990936 0.248175784945488 0.129863902926445 45.76174166654482 40.0 0.0 no 4979 chrVII_1042981r 15416 essential YGR274C 92 + AATCGGGTCATACATTGGCG I|32|M silent|ATC>ATT|I|32 TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 0.5552226802667363 P46677 0.9598389863967896 0.13275837898254395 1.8768999576568604 48.05709055567718 50.0 0.0 no 4980 chrVII_1043045 15419 essential YGR274C 31 - TTCATCTTCGTTGGCCAAGT E|17|Q E|17|K D|16|H D|16|N TAF1 TATA binding protein-Associated Factor 1066.0 0 0 0 0 -1.377395094650627 P46677 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.0690242201089859 0.05615842714905739 0.008040014654397964 0.02404191344976425 -0.3274399936199188 -0.2983199954032898 1.2241400480270386 0.8873800039291382 52.27408326036806 45.0 0.0 no 4981 chrVII_1045864 15421 essential YGR277C 678 - ATCTCGGGTACTTTCCCTGT E|232|D silent|GAG>GAA|E|232 E|232|Q E|232|K CAB4 Coenzyme A Biosynthesis 305.0 0 0 0 0 0.013179643773260169 P53332 0.94931298494339 0.956179976463318 0.9475290179252625 0.29640984535217285 0.06845846772193909 0.05919039249420166 57.20219984808483 50.0 0.0 no 4982 chrVII_1045909 15426 essential YGR277C 633 - ACTAGTTCTACGGAGAGATC V|218|L V|218|I CAB4 Coenzyme A Biosynthesis 305.0 0 0 0 0 1.3498276081953997 P53332 0.9539830088615416 0.9574310183525084 0.635109543800354 0.8050857186317444 44.85856078673197 45.0 0.0 no 4983 chrVII_1046035r 15428 essential YGR277C 504 + ACGTCACAAAGGTTAATTTG T|169|R T|169|M S|170|* S|170|L CAB4 Coenzyme A Biosynthesis 305.0 0 0 0 0 0.1675967809184445 P53332 0.9476869702339172 0.9502379894256592 0.9298099875450134 0.006328640505671501 0.0041911364533007145 0.1854914426803589 38.463078686731755 35.0 0.0 no 4984 chrVII_1046046r 15429 essential YGR277C 493 + CTACATTCATCACGTCACAA T|166|R T|166|I CAB4 Coenzyme A Biosynthesis 305.0 0 0 0 0 0.03335876049759287 P53332 0.9476869702339172 0.9472420215606691 0.0167684406042099 0.01649680733680725 43.850039831857536 40.0 0.0 no 4985 chrVII_1046171r 15433 essential YGR277C 368 + TGCATTACACGATAATATAA A|124|G A|124|V CAB4 Coenzyme A Biosynthesis 305.0 0 0 0 0 -0.09844466405911778 P53332 0.9484469890594482 0.9504740238189696 0.3680708110332489 0.2762144207954407 34.760574462757056 25.0 0.0 no 4986 chrVII_1046189 15434 essential YGR277C 353 - ATGCATAATGTTCTATACTA A|124|P A|124|T CAB4 Coenzyme A Biosynthesis 305.0 0 0 0 0 0.502667469131558 P53332 0.9573720097541808 0.9523990154266356 0.27936697006225586 0.5545672774314879 38.171623110399366 25.0 0.0 no 4987 chrVII_1046232 15435 essential YGR277C 310 - TAGCTTCCAAGTTTCAAAAG K|109|N silent|AAG>AAA|K|109 W|108|C W|108|* CAB4 Coenzyme A Biosynthesis 305.0 0 0 0 0 -0.36328295936572935 P53332 0.9355990290641784 0.8858469724655151 0.2871147692203522 0.15791963040828705 40.11173198994669 35.0 0.0 no 4988 chrVII_1046402r 15440 essential YGR277C 137 + ATTCAAAACCTCATTCCAGT F|47|L silent|TTC>TTT|F|47 CAB4 Coenzyme A Biosynthesis 305.0 0 0 0 0 0.4894180102640753 P53332 0.9387490153312684 0.27136772871017456 44.59889711955043 35.0 0.0 no 4989 chrVII_1046863 15444 essential YGR278W 132 + TTTCAAGTCAATATACTTAT Q|46|E Q|46|* CWC22 Complexed With Cef1p 577.0 0 0 0 0 -0.16738394486229974 P53333 0.9590039849281312 0.6652505993843079 34.60077515206564 20.0 1.0 no 4990 chrVII_1047237r 15448 essential YGR278W 509 - ACTTCTCCCAAATCATATCA K|176|N silent|AAG>AAA|K|176 E|175|D silent|GAG>GAA|E|175 CWC22 Complexed With Cef1p 577.0 0 0 0 0 -0.5266579234438982 P53333 0.9355990290641784 0.94931298494339 0.0 0.2079019844532013 45.49901002993289 35.0 1.0 no 4991 chrVII_1047862 15453 essential YGR278W 1131 + ACTGACCAACTGCGAATCTT T|378|S T|378|I D|379|E silent|GAC>GAT|D|379 CWC22 Complexed With Cef1p 577.0 0 0 0 0 -0.5672664700895353 P53333 0.9491789937019348 0.9472420215606691 0.9532920122146606 0.10038239508867264 0.020514748990535736 0.6229610443115234 46.50603256199332 45.0 1.0 no 4992 chrVII_1047867r 15454 essential YGR278W 1139 - ACTTACCTAAGATTCGCAGT K|386|N silent|AAG>AAA|K|386 G|385|A G|385|D CWC22 Complexed With Cef1p 577.0 0 0 0 0 -0.1149778293548718 P53333 0.9355990290641784 0.9499930143356324 0.9446240067481996 0.019152306020259857 0.0 0.0 46.504886921540276 40.0 1.0 no 4993 chrVII_1047872 15456 essential YGR278W 1141 + TGCGAATCTTAGGTAAGTTT R|382|G R|382|* CWC22 Complexed With Cef1p 577.0 0 0 0 0 -0.8800767718139206 P53333 0.8994590044021606 0.0 42.30451093183814 35.0 1.0 no 4994 chrVII_1051264 15459 essential YGR280C 442 - CCTCTTTCGTTTCTTCGCGT K|153|N silent|AAG>AAA|K|153 R|154|T R|154|K PXR1 PinX1-Related gene 271.0 0 0 0 0 1.3071392075766093 P53335 0.9355990290641784 0.932735025882721 0.955805003643036 0.30246931314468384 0.5346620082855225 1.0 56.12723757883606 50.0 0.0 no 4995 chrVII_1051292 15460 essential YGR280C 414 - TTTCTTAACTTGTGAGTCTT R|144|T R|144|K PXR1 PinX1-Related gene 271.0 0 1 0 0 0.08454615791401178 P53335 0.932735025882721 0.955805003643036 0.5642143487930298 0.925272524356842 42.467855702916495 30.0 0.0 no 4996 chrVII_1051332 15461 essential YGR280C 374 - AAACTTCACCCTTCACAAAA V|131|L V|131|I E|130|Q E|130|K PXR1 PinX1-Related gene 271.0 0 0 0 0 0.6143284914249256 P53335 0.9539830088615416 0.9574310183525084 0.956179976463318 0.9475290179252625 0.4550570845603943 0.16977982223033905 0.24433885514736176 0.2305918782949448 41.153051371156494 35.0 0.0 no 4997 chrVII_1051529r 15466 essential YGR280C 174 + TCAATTAAGGACGACAACGT S|59|* S|59|L PXR1 PinX1-Related gene 271.0 0 1 0 0 -0.2461646813648105 P53335 0.9298099875450134 0.035982396453618996 39.7534940278186 40.0 0.0 no 4998 chrVII_1051542r 15467 essential YGR280C 161 + GCATATCAAAGTGTCAATTA H|55|D H|55|Y I|56|M silent|ATC>ATT|I|56 PXR1 PinX1-Related gene 271.0 0 0 0 0 0.18768767413663584 P53335 0.9473130106925964 0.9489949941635132 0.9598389863967896 0.0 0.0 0.019522052258253098 38.476879400101716 30.0 0.0 no 4999 chrVII_1051688r 15472 essential YGR280C 15 + ACAAGAACCAAACAGCGGTT T|6|R T|6|I PXR1 PinX1-Related gene 271.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.3674500809759679 P53335 0.9476869702339172 0.9472420215606691 0.10197872668504716 0.13958202302455902 43.75866729361991 45.0 0.0 no 5000 chrVII_1051693r 15473 essential YGR280C 10 + CAGCTACAAGAACCAAACAG A|5|G A|5|V T|6|R T|6|I PXR1 PinX1-Related gene 271.0 0 1 0 0 0.6283507774624008 P53335 0.9484469890594482 0.9504740238189696 0.9476869702339172 0.9472420215606691 1.0 0.02314539067447185 0.10197872668504716 0.13958202302455902 40.335937677081226 45.0 0.0 no 5001 chrVIII_54895 15474 high_effect YHL025W 44 + GCGCCAACAATACTACTCTG silent|CGC>CGG|R|16 silent|CGC>CGT|R|16 R|16|G R|16|C SNF6 Sucrose NonFermenting 332.0 0 0 0 0 0.27496408048773385 P18888 0.8994590044021606 0.8926740288734436 47.612300867116566 50.0 1.0 no 5002 chrVIII_54894 15475 high_effect YHL025W 43 + CGCGCCAACAATACTACTCT R|16|G R|16|C silent|CGC>CGG|R|16 silent|CGC>CGT|R|16 SNF6 Sucrose NonFermenting 332.0 0 0 0 0 0.6875554657126921 P18888 0.8994590044021606 0.8926740288734436 48.60175185757032 50.0 1.0 no 5003 chrVIII_54965r 15482 high_effect YHL025W 117 - TCCGCGAAGCTCGTCAACGA silent|GCG>GCC|A|45 silent|GCG>GCA|A|45 E|46|Q E|46|K SNF6 Sucrose NonFermenting 332.0 0 0 0 0 -1.9323131642810016 P18888 0.956179976463318 0.9475290179252625 52.6532746984176 60.0 1.0 no 5004 chrVIII_55229r 15490 high_effect YHL025W 381 - GACTTCTCAATTCTGTCGCA K|133|N silent|AAG>AAA|K|133 E|132|D silent|GAG>GAA|E|132 SNF6 Sucrose NonFermenting 332.0 0 0 0 0 -0.003651248511015704 P18888 0.9355990290641784 0.94931298494339 0.3037551343441009 0.3992845118045807 49.440667971728146 45.0 1.0 no 5005 chrVIII_55578r 15506 high_effect YHL025W 730 - CTTCTGCCTGATACGCTCCT Q|249|H silent|CAG>CAA|Q|249 R|248|S silent|AGG>AGA|R|248 SNF6 Sucrose NonFermenting 332.0 0 0 0 0 0.8087847640447736 P18888 0.9570760130882264 0.9087679982185364 0.1850796788930893 0.2942807674407959 57.66242742116759 55.00000000000001 1.0 no 5006 chrVIII_75480 15508 essential YHL015W 68 + AATCACTTTGACCTCCACCA I|24|M silent|ATC>ATT|I|24 T|25|S T|25|I RPS20 Ribosomal Protein of the Small subunit 121.0 0 1 0 0 0.2004276386842197 P38701 0.06482353806495668 0.04378245770931244 0.020223181694746014 0.39287999272346497 1.127060055732727 -1.940160036087036 51.50059016767796 45.0 1.0 no 5007 chrVIII_75527r 15509 essential YHL015W 118 - TTCAGCGTTCTTGACAATGT E|46|Q E|46|K A|45|P A|45|T RPS20 Ribosomal Protein of the Small subunit 121.0 0 1 0 0 0.16186944259375047 P38701 0.07774676382541656 1.0 0.007187847513705492 0.1280706822872162 -0.3199000060558319 -0.5303199887275696 4.473139762878418 2.0106201171875 46.56673284313672 40.0 1.0 no 5008 chrVIII_75573 15513 essential YHL015W 161 + TCCAGTCAGACTACCAACCA P|55|R P|55|L P|55|A P|55|S RPS20 Ribosomal Protein of the Small subunit 121.0 0 1 0 0 -1.3613211421799796 P38701 0.0 0.0 0.0 0.0 2.00440001487732 0.06661999970674515 1.1891000270843506 2.241179943084717 52.74164917305927 50.0 1.0 no 5009 chrVIII_75608r 15515 essential YHL015W 199 - ACCATTTGGAGTCTTTCTGG G|73|R G|73|S G|73|A G|73|D RPS20 Ribosomal Protein of the Small subunit 121.0 0 1 0 0 -5.157455081085892 P38701 0.0010852327104657886 0.05677800253033637 0.05131613090634346 0.001360177993774414 -0.2109600007534027 -0.12933999300003052 -0.2511999905109405 -0.07751999795436859 50.35796921249164 45.0 1.0 yes 5010 chrVIII_75611r 15516 essential YHL015W 202 - TTCACCATTTGGAGTCTTTC E|74|Q E|74|K G|73|A G|73|D RPS20 Ribosomal Protein of the Small subunit 121.0 0 1 0 0 -0.8486745092118068 P38701 0.08487772941589355 0.032810647040605545 0.05131613090634346 0.001360177993774414 0.2322400063276291 0.0828000009059906 -0.2511999905109405 -0.07751999795436859 48.69076579284257 40.0 1.0 no 5011 chrVIII_120635r 15519 essential YHR007C 1026 + GAACAAATGCGTGTTTTGGA Q|344|E Q|344|* ERG11 ERGosterol biosynthesis 530.0 0 0 0 0 -1.5870732727016268 P10614 0.8788300156593323 0.00728692440316081 0.422760009765625 42.106510109160865 40.0 0.0 no 5012 chrVIII_120709r 15524 essential YHR007C 952 + CTTCTGCTGCCACTTCTGCT S|319|C S|319|F A|320|G A|320|V ERG11 ERGosterol biosynthesis 530.0 0 0 0 0 0.2641613518260805 P10614 0.8231639862060547 0.8180429935455322 0.9542239904403688 0.8906689882278442 0.0017322192434221506 0.0008679467136971653 0.050092656165361404 0.015691664069890976 -0.237639993429184 3.052419900894165 1.8068599700927732 2.7795000076293945 0.6977999806404114 3.376800060272217 59.904812747369135 55.00000000000001 0.0 no 5013 chrVIII_120787 15525 essential YHR007C 877 - CATCTTCACACCATCCTTGT K|298|N silent|AAG>AAA|K|298 silent|GTG>GTC|V|297 silent|GTG>GTA|V|297 ERG11 ERGosterol biosynthesis 530.0 0 1 0 0 -0.2545847156192235 P10614 0.993561029434204 0.1631913185119629 0.7057600021362305 52.833728331942844 45.0 0.0 no 5014 chrVIII_120873r 15526 essential YHR007C 788 + TACTTACATGTCTTTGATTA T|264|S T|264|I Y|265|* silent|TAC>TAT|Y|265 ERG11 ERGosterol biosynthesis 530.0 0 1 0 0 0.3639144086644071 P10614 0.9411500096321106 1.005489945411682 0.21225348114967346 0.6941296458244324 0.6214399933815002 0.04129999876022339 38.896434290991465 25.0 0.0 no 5015 chrVIII_120896r 15528 essential YHR007C 765 + CACGCTCAAAAGGCTATCTC H|256|Q silent|CAC>CAT|H|256 A|257|G A|257|V ERG11 ERGosterol biosynthesis 530.0 0 1 0 0 -4.73122051909818 P10614 1.019819974899292 0.8563870191574097 0.8558239936828613 0.545476496219635 0.0 0.0 -0.7910199761390686 1.8289999961853027 4.390480041503906 -0.5198000073432922 1.7990000247955322 3.5585999488830566 46.49307477654753 50.0 0.0 yes 5016 chrVIII_120923 15529 essential YHR007C 741 - CTCTTTCTATAGTGTTCCAA K|253|N silent|AAG>AAA|K|253 R|252|T R|252|K ERG11 ERGosterol biosynthesis 530.0 0 0 0 0 0.7800322854095698 P10614 0.9495689868927002 0.8545699715614319 1.0135400295257568 0.00878189317882061 0.1601264774799347 0.807643473148346 0.755840003490448 0.40939998626708973 -0.0545400008559227 46.148063584191725 35.0 0.0 no 5017 chrVIII_120939r 15530 essential YHR007C 722 + CGTCTTCCCTAACTTACCAT silent|GTC>GTG|V|242 silent|GTC>GTT|V|242 F|243|L silent|TTC>TTT|F|243 ERG11 ERGosterol biosynthesis 530.0 0 0 0 0 0.5330186463423501 P10614 1.0028400421142578 0.505806028842926 0.4539999961853027 0.04919999837875366 51.65583219540054 45.0 0.0 no 5018 chrVIII_121038r 15532 essential YHR007C 623 + TTCAAGATCATTATTGGGTA S|209|* S|209|L ERG11 ERGosterol biosynthesis 530.0 0 0 0 0 -1.956350753466137 P10614 0.8878409862518309 0.004565214738249779 -1.8805199861526491 40.41323470794117 30.0 0.0 no 5019 chrVIII_121061 15534 essential YHR007C 603 - GCGGTGAAAATAGTCATTTC A|208|P A|208|T ERG11 ERGosterol biosynthesis 530.0 0 0 0 0 0.6173383280910572 P10614 0.8774539828300476 0.9005690217018127 0.0 0.0 6.849639892578125 1.3970600366592407 41.566045654664826 40.0 0.0 no 5020 chrVIII_121472 15538 essential YHR007C 192 - ACAACAGCACTACCGACCCA V|71|L V|71|M V|70|L V|70|I ERG11 ERGosterol biosynthesis 530.0 0 0 0 0 -0.3347069349446414 P10614 1.0118000507354736 0.9902430176734924 1.0148299932479858 1.0225600004196167 0.18801458179950714 0.06584148108959198 0.07719545066356659 0.8040041923522949 -0.5546000003814697 -1.161120057106018 -0.6101800203323364 -0.6247400045394897 -0.8935999870300293 -1.045199990272522 -0.8564000129699707 -0.6632000207901001 -0.7128000259399414 -0.5827999711036682 -0.9391999840736388 -0.963599979877472 53.14087887569065 55.00000000000001 0.0 no 5021 chrVIII_121602r 15539 essential YHR007C 59 + TCATTTCTTGGCTTTACCAT H|21|D H|21|Y F|22|L silent|TTC>TTT|F|22 ERG11 ERGosterol biosynthesis 530.0 0 0 0 0 -0.9578819999562946 P10614 1.0133099555969238 1.0173900127410889 0.9991899728775024 0.309186190366745 1.0 1.0 -0.03643999993801117 -0.7178999781608582 0.06784000247716904 48.667347120515096 35.0 0.0 no 5022 chrVIII_127123r 15542 high_effect YHR010W 44 - TCTTACCGGCGTAACGACCA K|21|N silent|AAG>AAA|K|21 G|20|A G|20|D 0 1 0 0 -2.4237241154577185 P0C2H6 0.9355990290641784 0.9499930143356324 0.9446240067481996 0.03044215030968189 0.016305191442370415 0.00796007551252842 0.8134999871253967 3.318099975585937 4.367599964141847 5.544400215148926 9.550600051879883 52.43279389664633 55.00000000000001 1.0 yes 5023 chrVIII_127229r 15548 high_effect YHR010W 150 - TGCTTCTTGGTGACCTTCAA K|56|N silent|AAG>AAA|K|56 K|55|N silent|AAG>AAA|K|55 0 1 0 0 -0.8589207867590479 P0C2H6 0.9355990290641784 0.9355990290641784 0.33915871381759644 0.029850732535123825 0.2823399901390076 0.19643999636173248 1.1171000003814695 51.44900316791274 45.0 1.0 no 5024 chrVIII_129765 15551 exception YHR012W 165 + AACAATATAACAATCGTAAG N|56|K silent|AAC>AAT|N|56 VPS29 Vacuolar Protein Sorting 282.0 0 0 0 0 0.2508123403096346 P38759 0.9439849853515624 0.05101847276091576 30.19301345541368 25.0 1.0 no 5025 chrVIII_130085 15554 exception YHR012W 485 + GCCAATTGTCTTTGATGTTG P|163|R P|163|L P|163|A P|163|S VPS29 Vacuolar Protein Sorting 282.0 0 0 0 0 -0.5808564608281969 P38759 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.06903859227895738 0.04313354194164276 0.11831823736429214 0.0891222357749939 46.62260628013559 40.0 1.0 no 5026 chrVIII_130086r 15555 exception YHR012W 489 - TCCTCAACATCAAAGACAAT E|169|D silent|GAG>GAA|E|169 D|170|H D|170|N VPS29 Vacuolar Protein Sorting 282.0 0 0 0 0 0.5780944790850312 P38759 0.94931298494339 0.9486550092697144 0.956179976463318 0.3973284959793091 0.02091888897120953 0.06832636892795563 39.56337226857932 35.0 1.0 no 5027 chrVIII_142394r 15572 essential YHR019C 1142 + ACAATTGAATCCAAACTTTA Q|382|E Q|382|* DED81 Defines Essential Domain 554.0 0 1 0 0 0.22633613858094986 P38707 0.9590039849281312 1.0 35.6499982138908 25.0 0.0 no 5028 chrVIII_142545 15574 essential YHR019C 994 - GGACAAATGTCTTCTTGTGT L|337|F silent|TTG>TTA|L|337 DED81 Defines Essential Domain 554.0 0 0 0 0 -0.5048461636479865 P38707 0.9587849974632264 0.0071787252090871325 -1.5923999547958374 45.25286398163763 40.0 0.0 no 5029 chrVIII_142702r 15577 essential YHR019C 834 + GTGCAAACTCAAGTCGAAGG Q|280|E Q|280|* DED81 Defines Essential Domain 554.0 0 0 0 0 -2.5230622214043064 P38707 0.9590039849281312 0.010599858127534391 43.697399598378695 50.0 0.0 yes 5030 chrVIII_142711 15578 essential YHR019C 828 - ACTTGAGTTTGCACCATACA V|283|L V|283|I DED81 Defines Essential Domain 554.0 0 0 0 0 0.42210653124334097 P38707 0.9539830088615416 0.9574310183525084 0.040323875844478614 0.053154300898313515 0.026799999177455902 -0.5766000151634216 47.86410806714185 40.0 0.0 no 5031 chrVIII_142800 15579 essential YHR019C 739 - GACTTTCATGACTGCAGACA V|253|L V|253|I M|251|I M|251|I DED81 Defines Essential Domain 554.0 0 0 0 0 0.2378027082228021 P38707 0.9539830088615416 0.9574310183525084 0.9553959965705872 0.9553959965705872 0.4628371000289917 0.43461331725120544 0.047697175294160836 0.047697175294160836 0.9800000190734864 0.9800000190734864 47.03214104113255 45.0 0.0 no 5032 chrVIII_142815 15581 essential YHR019C 724 - AGACAAGGCATCTCCTCTCA L|247|F silent|TTG>TTA|L|247 DED81 Defines Essential Domain 554.0 0 0 0 0 -0.2704978912071376 P38707 0.9587849974632264 0.6815530061721802 0.3472000062465668 53.06325752285818 50.0 0.0 no 5033 chrVIII_142945 15587 essential YHR019C 594 - ACATTCAATTCAACACCACC V|205|L V|205|I L|203|F silent|TTG>TTA|L|203 DED81 Defines Essential Domain 554.0 0 0 0 0 0.4070262700519604 P38707 0.9539830088615416 0.9574310183525084 0.9587849974632264 0.062480337917804725 0.07239535450935364 0.007472784258425236 44.6952383187629 40.0 0.0 no 5034 chrVIII_143024r 15591 essential YHR019C 512 + ACAAACTTTGGACCTGACTT Q|172|E Q|172|* T|173|S T|173|I DED81 Defines Essential Domain 554.0 0 0 0 0 -0.12437910188770032 P38707 0.9590039849281312 0.9491789937019348 0.9472420215606691 0.23779331147670746 0.04555583745241165 0.06546125560998918 44.192478405849506 40.0 0.0 no 5035 chrVIII_143065r 15593 essential YHR019C 471 + TTCATTCAATGTGTCTTGTC F|158|L silent|TTC>TTT|F|158 Q|160|E Q|160|* DED81 Defines Essential Domain 554.0 0 0 0 0 -0.2023510598346175 P38707 0.9387490153312684 0.9590039849281312 0.2693590223789215 0.0 0.4733999967575073 44.396738013330776 35.0 0.0 no 5036 chrVIII_143123 15595 essential YHR019C 416 - TCTTGTTAGAACGTAATCTA K|145|N silent|AAG>AAA|K|145 DED81 Defines Essential Domain 554.0 0 0 0 0 -2.077987842335085 P38707 0.9355990290641784 0.08703688532114029 0.6574000120162964 38.61995688906853 30.0 0.0 yes 5037 chrVIII_143190 15598 essential YHR019C 349 - GTCATAAATTCTAGTCTTAA D|123|H D|123|N DED81 Defines Essential Domain 554.0 0 1 0 0 -0.19511559995368485 P38707 0.9486550092697144 0.956179976463318 0.032165784388780594 0.2605355381965637 36.244947561694524 25.0 0.0 no 5038 chrVIII_143220 15599 essential YHR019C 319 - TAGCGATTCGTCCTCCTTAA silent|TCG>TCC|S|112 silent|TCG>TCA|S|112 DED81 Defines Essential Domain 554.0 0 0 0 0 0.4998673254750643 P38707 51.04373754894198 45.0 0.0 no 5039 chrVIII_143234r 15601 essential YHR019C 302 + TGCTTTGAATATCACCATTA A|102|G A|102|V DED81 Defines Essential Domain 554.0 0 1 0 0 0.4519018991437639 P38707 0.9484469890594482 0.9504740238189696 0.02117905206978321 0.00663328031077981 41.99985474609901 30.0 0.0 no 5040 chrVIII_143432r 15609 essential YHR019C 104 + TCAACAGAAGAGCGATGCCA Q|36|E Q|36|* Q|37|E Q|37|* DED81 Defines Essential Domain 554.0 0 1 0 0 -0.6776691776061843 P38707 0.9590039849281312 0.9590039849281312 0.3835597634315491 0.8537020087242126 47.52236029306721 50.0 0.0 no 5041 chrVIII_144018r 15613 essential YHR020W 25 - CTTCTCATTCACACACAACT E|14|D silent|GAG>GAA|E|14 E|14|Q E|14|K 688.0 0 1 0 0 -1.2027044868526342 P38708 0.94931298494339 0.956179976463318 0.9475290179252625 44.983826445418636 40.0 1.0 no 5042 chrVIII_144044r 15614 essential YHR020W 51 - ACCGCAACGGCAGATTCAGC silent|GCG>GCC|A|23 silent|GCG>GCA|A|23 V|24|L V|24|M 688.0 0 0 0 0 0.01720248763647769 P38708 0.9539830088615416 0.9587630033493042 0.2743842899799347 0.09525499492883682 54.036994882261524 60.0 1.0 no 5043 chrVIII_144043 15615 essential YHR020W 47 + TCCTGCTGAATCTGCCGTTG P|17|R P|17|L P|17|A P|17|S 688.0 0 1 0 0 0.5403843277013725 P38708 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 54.978033506207794 55.00000000000001 1.0 no 5044 chrVIII_144567 15637 essential YHR020W 571 + AAGCGTTGGATTTCCCAGGC A|192|G A|192|V 688.0 0 0 0 0 -0.8858087342742759 P38708 0.9484469890594482 0.9504740238189696 0.031373728066682816 0.008716508746147156 0.1648000031709671 0.4273799955844879 55.38284765901597 55.00000000000001 1.0 no 5045 chrVIII_144937 15642 essential YHR020W 941 + ACTAAACCAATGGAATTCTG L|315|V silent|CTA>TTA|L|315 N|316|K silent|AAC>AAT|N|316 688.0 0 1 0 0 0.04134148495441832 P38708 0.9512209892272948 0.9439849853515624 0.02024887502193451 0.0023615984246134762 0.6447799801826477 37.81217320743275 35.0 1.0 no 5046 chrVIII_144999r 15644 essential YHR020W 1006 - TTCTTGCCACAAGAATTCTC E|342|Q E|342|K W|340|C W|340|* 688.0 0 0 0 0 -6.3494464814552405 P38708 0.956179976463318 0.9475290179252625 0.8858469724655151 0.0 0.0 0.0 45.3875020867419 40.0 1.0 yes 5047 chrVIII_145072 15647 essential YHR020W 1076 + AATCTTAGATTTCTACGCTG I|360|M silent|ATC>ATT|I|360 688.0 0 0 0 0 0.2813341268344185 P38708 0.9598389863967896 0.01444519218057394 41.39649947344589 35.0 1.0 no 5048 chrVIII_145166 15649 essential YHR020W 1170 + GACTTCACCACAACTTGTGA D|391|E silent|GAC>GAT|D|391 F|392|L silent|TTC>TTT|F|392 688.0 0 1 0 0 0.6676979968722396 P38708 0.9532920122146606 0.9387490153312684 0.15107347071170807 0.007747118826955556 -1.25901997089386 47.312666487446 45.0 1.0 no 5049 chrVIII_145118r 15650 essential YHR020W 1125 - GTCTTTCTACCCTTAACCAC K|381|N silent|AAG>AAA|K|381 R|380|T R|380|K 688.0 0 0 0 0 -0.3488589967480633 P38708 0.9355990290641784 0.932735025882721 0.955805003643036 0.0 0.03482111915946007 0.14110185205936432 51.52234342777614 45.0 1.0 no 5050 chrVIII_145417 15655 essential YHR020W 1421 + CCAATCCGTTGTCATTCCAG Q|475|E Q|475|* S|476|C S|476|F 688.0 0 0 0 0 -0.5857858969240753 P38708 0.9590039849281312 0.945252001285553 0.9294660091400146 0.002787966281175613 0.02365456894040108 0.016601182520389557 52.666403847860295 50.0 1.0 no 5051 chrVIII_151711r 15660 essential YHR023W 48 - ACGAAAACTTCTTTCTCATC V|23|L V|23|I 0 0 0 0 1.0795430293263992 P08964 0.9539830088615416 0.9574310183525084 0.07272501289844513 0.1068417951464653 39.64433420466338 35.0 1.0 no 5052 chrVIII_151867r 15664 essential YHR023W 204 - TCAAAAGTCGATGGGTTAAC D|75|H D|75|N 0 0 0 0 1.1422469320685664 P08964 0.9486550092697144 0.956179976463318 0.0 0.0 39.23142804049303 40.0 1.0 no 5053 chrVIII_151820r 15665 essential YHR023W 157 - CACTAGATTAGAAACCTCTG V|59|L V|59|M 0 0 0 0 0.31128126649838994 P08964 0.9539830088615416 0.9587630033493042 0.7752098441123962 0.23626169562339785 40.490503829300735 40.0 1.0 no 5054 chrVIII_151876r 15667 essential YHR023W 213 - TCTACTTTGTCAAAAGTCGA E|78|Q E|78|K V|77|L V|77|I 0 0 0 0 0.2529363072859786 P08964 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.03576517105102539 0.038468290120363235 0.049069829285144806 0.42474564909935 40.572648080555894 35.0 1.0 no 5055 chrVIII_151947r 15669 essential YHR023W 284 - CACAATCGTACCTCTTTTCT C|101|S C|101|Y D|100|H D|100|N 0 0 0 0 0.7766912234188146 P08964 0.9421560168266296 0.9290120005607604 0.9486550092697144 0.956179976463318 0.2197132557630539 0.04423987120389938 0.1637459695339203 0.4846058487892151 47.43244685917711 40.0 1.0 no 5056 chrVIII_151982r 15671 essential YHR023W 319 - CACTAAAAATAAGCCGGAAT V|113|L V|113|M 0 0 0 0 -1.8361725695272144 P08964 0.9539830088615416 0.9587630033493042 0.0 0.0 36.535640172124936 35.0 1.0 no 5057 chrVIII_152182 15676 essential YHR023W 516 + GATCAATCTATTTTAGTCAC Q|174|E Q|174|* 0 0 0 0 -0.2055648571082808 P08964 0.9590039849281312 0.0 38.65469169562834 30.0 1.0 no 5058 chrVIII_152281 15678 essential YHR023W 615 + TCCAATATAGCTCCTGTTAG silent|TCC>TCG|S|206 silent|TCC>TCT|S|206 S|206|C S|206|F 0 0 0 0 -0.6759463579224038 P08964 0.945252001285553 0.9294660091400146 47.256799588145846 40.0 1.0 no 5059 chrVIII_152293r 15679 essential YHR023W 630 - ACAATAGAACTACCACTAAC V|217|L V|217|I 0 0 0 0 -0.1323300168766781 P08964 0.9539830088615416 0.9574310183525084 0.6640378832817078 0.4004970788955689 37.21100311503813 35.0 1.0 no 5060 chrVIII_152818 15686 essential YHR023W 1152 + AGCGCAATTTGTAGCAATTT S|385|R silent|AGC>AGT|S|385 A|386|G A|386|V 0 0 0 0 -0.6508610450620074 P08964 0.9417110085487366 0.9484469890594482 0.9504740238189696 0.3532963097095489 0.3101716041564941 0.3609939515590668 44.12925281603743 35.0 1.0 no 5061 chrVIII_152878r 15688 essential YHR023W 1215 - TCTTTTCCGGCTTTTGATCT E|412|Q E|412|K G|410|A G|410|E 0 0 0 0 0.3009959812972111 P08964 0.956179976463318 0.9475290179252625 0.9499930143356324 0.9438679814338684 0.03016356192529201 0.023740546777844432 0.0 0.0 51.70569829374085 40.0 1.0 no 5062 chrVIII_152954 15690 essential YHR023W 1288 + TATCAAGAAATCTTTATGAG S|431|* S|431|L 0 0 0 0 -1.3457718608109712 P08964 0.9298099875450134 0.0 32.035862268525136 25.0 1.0 no 5063 chrVIII_152973 15691 essential YHR023W 1307 + GCGGTTGTTCGGATATATTG R|437|G R|437|W 0 0 0 0 -1.2127402105615446 P08964 0.8994590044021606 0.9448130130767822 0.238483801484108 0.013977005146443844 46.994475584842064 45.0 1.0 no 5064 chrVIII_153329 15697 essential YHR023W 1663 + ACTCTAAACTGATCTCAACT S|556|C S|556|F Y|555|* silent|TAC>TAT|Y|555 0 0 0 0 -0.10233138031552086 P08964 0.945252001285553 0.9294660091400146 0.011819443665444851 0.01084724348038435 40.083890448428065 35.0 1.0 no 5065 chrVIII_153398 15698 essential YHR023W 1732 + TCATTTTGAAACACTATGCT F|578|L silent|TTC>TTT|F|578 0 0 0 0 -0.38455023817312506 P08964 0.9387490153312684 0.0 39.53834260863494 30.0 1.0 no 5066 chrVIII_153572r 15703 essential YHR023W 1909 - AACTTCTTGGTTGGAGATGT V|643|L V|643|I E|642|Q E|642|K 0 0 0 0 -0.1874821610337732 P08964 0.9539830088615416 0.9574310183525084 0.956179976463318 0.9475290179252625 45.92111194029736 40.0 1.0 no 5067 chrVIII_153803r 15708 essential YHR023W 2140 - CCTATTTGGGTAACCTTCTC R|720|T R|720|K 0 0 0 0 -2.300520471512232 P08964 0.932735025882721 0.955805003643036 0.0 0.0 50.33531324929726 45.0 1.0 yes 5068 chrVIII_153936 15710 essential YHR023W 2270 + TCTTCTAACGTCTTTGCAAC L|758|V L|758|F L|759|V silent|CTA>TTA|L|759 0 0 0 0 -0.1240229907321983 P08964 0.9512209892272948 0.9587849974632264 0.9512209892272948 0.23316152393817904 0.026389185339212414 0.04874271526932717 44.42928338150404 40.0 1.0 no 5069 chrVIII_154063 15712 essential YHR023W 2397 + AAACTAACAGCAACTATACG L|801|V silent|CTA>TTA|L|801 0 0 0 0 -1.0192567490392237 P08964 0.9512209892272948 0.05041062086820602 2.9932000637054443 35.62492008822983 35.0 1.0 no 5070 chrVIII_154293r 15715 essential YHR023W 2630 - TCTTAGATTCCATTTCTTGA K|883|N silent|AAG>AAA|K|883 0 0 0 0 1.1324643484424135 P08964 0.9355990290641784 0.4469283223152161 44.16860936970335 30.0 1.0 no 5071 chrVIII_154554r 15718 essential YHR023W 2891 - GTTCTCTAATAGTTTCTTGA E|970|Q E|970|K R|969|T R|969|K 0 0 0 0 0.3505099708396835 P08964 0.956179976463318 0.9475290179252625 0.932735025882721 0.955805003643036 0.470789760351181 0.519345223903656 0.600398063659668 0.8928245902061462 42.12095039426862 30.0 1.0 no 5072 chrVIII_154556 15719 essential YHR023W 2890 + TTCAAGAAACTATTAGAGAA Q|965|E Q|965|* 0 0 0 0 1.316489119592838 P08964 0.9590039849281312 0.3198321759700775 31.609249026374755 25.0 1.0 no 5073 chrVIII_154859r 15722 essential YHR023W 3196 - ATCTGAATTTTCTGTTACAA D|1072|H D|1072|N 0 0 0 0 0.3858692380117836 P08964 0.9486550092697144 0.956179976463318 0.1081879734992981 0.5229593515396118 37.684754868058796 25.0 1.0 no 5074 chrVIII_155129r 15723 essential YHR023W 3466 - CTTCGTTTCTCTTTGGAAGT silent|ACG>ACC|T|1161 silent|ACG>ACA|T|1161 0 0 0 0 -1.0896286420892372 P08964 47.51148213190743 40.0 1.0 no 5075 chrVIII_155373r 15727 essential YHR023W 3710 - TTTCAGTAAACGCTAATTGA E|1243|Q E|1243|K 0 0 0 0 0.3055304547853029 P08964 0.956179976463318 0.9475290179252625 0.2844967246055603 0.25153064727783203 37.95428723024975 30.0 1.0 no 5076 chrVIII_155469 15728 essential YHR023W 3803 + ACTAGCATCTTCGTCTTTTG L|1269|V silent|CTA>TTA|L|1269 A|1270|G A|1270|V 0 0 0 0 0.4701363017110137 P08964 0.9512209892272948 0.9484469890594482 0.9504740238189696 0.0 0.0 0.0 47.51493451023612 40.0 1.0 no 5077 chrVIII_155854r 15731 essential YHR023W 4191 - TTCTTTATAATATCTCCGAC K|1403|N silent|AAG>AAA|K|1403 1 Series([], Name: modification, dtype: object) 0 0 0 0.2433134673840309 P08964 0.9355990290641784 0.4633955657482147 40.19601820687228 30.0 1.0 no 5078 chrVIII_155976r 15732 essential YHR023W 4313 - GCCTCAAGTCAAGAGTGAGT R|1444|T R|1444|K R|1444|S silent|AGG>AGA|R|1444 0 0 0 0 -0.2876825201490005 P08964 0.932735025882721 0.955805003643036 0.9087679982185364 0.17276182770729065 1.0 0.20720110833644867 50.69025290540441 50.0 1.0 no 5079 chrVIII_155975 15733 essential YHR023W 4309 + GCCAACTCACTCTTGACTTG Q|1438|E Q|1438|* S|1437|R silent|AGC>AGT|S|1437 0 0 0 0 -0.008235691506959658 P08964 0.9590039849281312 0.9417110085487366 1.0 0.1885976791381836 50.13901631272756 50.0 1.0 no 5080 chrVIII_158085r 15734 essential YHR024C 1085 + AACTGAAGACGAAGTCTCCA T|363|S T|363|I MAS2 Mitochondrial ASsembly 482.0 0 0 0 0 -0.3856427926263679 P11914 0.96737802028656 0.917581021785736 0.5094272494316101 0.045036416500806815 -0.5647000074386597 1.2771999835968018 43.861861587504336 45.0 0.0 no 5081 chrVIII_158150 15736 essential YHR024C 1023 - GCAATTACCTCAACCGCTTG A|348|P A|348|T MAS2 Mitochondrial ASsembly 482.0 0 0 0 0 1.100268569371082 P11914 0.8538699746131897 0.9370279908180236 0.21052630245685575 0.12098352611064912 5.106460094451903 0.5474399924278259 49.996103616338026 50.0 0.0 no 5082 chrVIII_158220r 15741 essential YHR024C 950 + TGCGTTCAACCATTCTTATT A|318|G A|318|V F|319|L silent|TTC>TTT|F|319 MAS2 Mitochondrial ASsembly 482.0 0 0 0 0 0.38976048535319896 P11914 0.8074820041656494 0.7927979826927185 0.800370991230011 0.05431729555130005 0.01773262396454811 0.011733881197869778 2.025000095367432 -0.3590599894523621 1.5805599689483645 1.5226099491119385 1.0618900060653689 1.3979820013046265 46.254138455632535 35.0 0.0 no 5083 chrVIII_158339r 15745 essential YHR024C 831 + ACATTACAAACTTTACTTGG T|278|R T|278|I Q|280|E Q|280|* MAS2 Mitochondrial ASsembly 482.0 0 0 0 0 -0.8465806509827248 P11914 0.5571590065956116 0.8442019820213318 0.7409330010414124 0.0094188516959548 0.08170762658119203 0.014205600135028362 10.570679664611816 -0.7634199857711792 0.5962200164794922 36.899987132180115 30.0 0.0 no 5084 chrVIII_158399r 15747 essential YHR024C 771 + CACATCCAGATCGGATTTGA H|258|Q silent|CAC>CAT|H|258 I|259|M silent|ATC>ATT|I|259 MAS2 Mitochondrial ASsembly 482.0 0 0 0 0 -0.15795850590408184 P11914 0.8323919773101807 0.8768230080604553 0.0070130471140146255 0.21029534935951236 0.869700014591217 0.032979998737573624 47.15076912669014 45.0 0.0 no 5085 chrVIII_158466 15752 essential YHR024C 707 - AACTTTCCCCGCCCGTATAT S|242|T S|242|N E|241|Q E|241|K MAS2 Mitochondrial ASsembly 482.0 0 0 0 0 -1.0155881437052123 P11914 0.9026849865913392 0.8179799914360046 0.8577359914779663 0.8043220043182373 0.4553684890270233 0.3484127521514893 0.4960545897483826 0.7595452666282654 0.891219973564148 0.0009599999757483602 -0.222680002450943 0.2632800042629242 56.59954295175044 50.0 0.0 no 5086 chrVIII_158467 15753 essential YHR024C 706 - ACTTTCCCCGCCCGTATATT S|242|T S|242|N E|241|Q E|241|K MAS2 Mitochondrial ASsembly 482.0 0 0 0 0 -1.5090714911884144 P11914 0.9026849865913392 0.8179799914360046 0.8577359914779663 0.8043220043182373 0.4553684890270233 0.3484127521514893 0.4960545897483826 0.7595452666282654 0.891219973564148 0.0009599999757483602 -0.222680002450943 0.2632800042629242 58.52161796688944 50.0 0.0 no 5087 chrVIII_158699r 15760 essential YHR024C 471 + TTGCACACAGCAGCATACTC H|159|D H|159|Y H|159|Q silent|CAC>CAT|H|159 MAS2 Mitochondrial ASsembly 482.0 0 0 0 0 -0.2540430931249797 P11914 0.5896900296211243 0.6699529886245728 0.7809900045394897 0.017707007005810738 0.004069414921104908 0.14205868542194364 2.7809200286865234 4.562620162963867 3.02701997756958 50.939864753584175 50.0 0.0 no 5088 chrVIII_158799 15764 essential YHR024C 374 - GTTCTTGCTCAGTAATCTTA E|131|Q E|131|K MAS2 Mitochondrial ASsembly 482.0 0 0 0 0 0.7128239188788159 P11914 0.7887459993362427 0.6888989806175232 0.013829639181494713 0.010728416964411736 3.1738998889923096 2.8442199230194087 45.986456143784324 35.0 0.0 no 5089 chrVIII_158865r 15767 essential YHR024C 305 + TCAGGCTTCTGTGTTCAACC Q|103|E Q|103|* A|104|G A|104|V MAS2 Mitochondrial ASsembly 482.0 0 0 0 0 -0.9989823353880299 P11914 0.7150869965553284 0.787244975566864 0.8249970078468323 0.0 0.02785271406173706 0.01226974744349718 1.4649399518966677 0.5307000279426575 4.037859916687012 0.8436020016670227 3.601501941680908 53.45461520203844 50.0 0.0 no 5090 chrVIII_158890 15769 essential YHR024C 283 - CATCAAATTTTCTCTAGACG L|100|F silent|TTG>TTA|L|100 MAS2 Mitochondrial ASsembly 482.0 0 0 0 0 0.4976408241673528 P11914 0.8696860074996948 0.04457148909568786 -0.8169000148773193 38.76511967506275 35.0 0.0 no 5091 chrVIII_158926r 15770 essential YHR024C 244 + AGACGTTGGAGTTACTGGGT T|83|R T|83|M MAS2 Mitochondrial ASsembly 482.0 0 0 0 0 0.22388907962267104 P11914 0.8544480204582214 0.8318660259246826 0.4904510974884033 0.09893670678138733 0.2848399877548218 -1.0321199893951416 50.70935500056111 50.0 0.0 no 5092 chrVIII_158956 15776 essential YHR024C 217 - TGCTCGGCCCTCGACGTGTT A|79|P A|79|T R|78|P R|78|Q MAS2 Mitochondrial ASsembly 482.0 0 0 0 0 -3.788814498396852 P11914 0.7913720011711121 0.9159430265426636 0.9211800098419191 0.9844030141830444 0.2378566265106201 0.5672957897186279 0.22955948114395144 0.4218553304672241 -0.35523998737335205 0.3632600009441376 0.8759599924087524 -0.3321000039577484 -1.0691599845886228 0.6530100107192993 61.78330321371038 65.0 0.0 yes 5093 chrVIII_159113r 15782 essential YHR024C 57 + AAGCTTTCGTCACTAGCGAA L|21|V L|21|F MAS2 Mitochondrial ASsembly 482.0 0 0 0 0 0.20480856804806505 P11914 0.9586309790611268 0.921321988105774 0.711124062538147 0.0507272444665432 1.7207399606704712 1.2217400074005127 1.5280419588088991 1.999642014503479 47.04421338954836 45.0 0.0 no 5094 chrVIII_159124 15783 essential YHR024C 49 - TGACGAAAGCTTAAAATTAT silent|TCG>TCC|S|22 silent|TCG>TCA|S|22 MAS2 Mitochondrial ASsembly 482.0 0 0 0 0 -0.3330229728153061 P11914 32.39833162296373 25.0 0.0 no 5095 chrVIII_160946 15785 high_effect YHR026W 102 + TACAAGCTTTTCACTGGACA Y|35|* silent|TAC>TAT|Y|35 L|37|V L|37|F VMA16 Vacuolar Membrane Atpase 213.0 0 0 0 0 0.6170894072716189 P23968 0.06026353687047959 0.017449455335736275 45.15469482871389 40.0 1.0 no 5096 chrVIII_160971r 15786 high_effect YHR026W 130 - GAACTTCCCGAAATTAATGT K|49|N silent|AAG>AAA|K|49 silent|GGG>GGC|G|48 silent|GGG>GGA|G|48 VMA16 Vacuolar Membrane Atpase 213.0 0 0 0 0 0.0753688285324661 P23968 0.4905921816825866 40.70591271851936 35.0 1.0 no 5097 chrVIII_161009r 15788 high_effect YHR026W 168 - CCAAGATTGGCCCACATATA G|63|R G|63|S VMA16 Vacuolar Membrane Atpase 213.0 0 0 0 0 -2.121517350033065 P23968 0.001989012351259589 0.007033908274024725 49.674728642400396 45.0 1.0 yes 5098 chrVIII_161037r 15790 high_effect YHR026W 196 - GACACTTAAGCCTACACAAA V|72|L V|72|I S|71|T S|71|N VMA16 Vacuolar Membrane Atpase 213.0 0 0 0 0 0.4418640127036674 P23968 0.024242136627435684 0.26739686727523804 0.0039956262335181245 0.0033074866514652967 0.18286000192165372 -1.7008600234985352 42.138005689116255 40.0 1.0 no 5099 chrVIII_161097r 15791 high_effect YHR026W 256 - ACGCACACCGGCACCAATCA silent|GTG>GTC|V|91 silent|GTG>GTA|V|91 R|92|P R|92|H VMA16 Vacuolar Membrane Atpase 213.0 0 0 0 0 -0.3281901252650113 P23968 0.048993408679962165 0.08977200835943222 4.26039981842041 3.5561299324035645 55.39902668443574 60.0 1.0 no 5100 chrVIII_161175r 15794 high_effect YHR026W 334 - GGCAATAATCAGACCGTAAA A|118|P A|118|T VMA16 Vacuolar Membrane Atpase 213.0 0 0 0 0 0.04530224507172444 P23968 0.01529769878834486 0.048721134662628174 6.571690082550049 4.232190132141113 41.36496265477382 40.0 1.0 no 5101 chrVIII_161246 15795 high_effect YHR026W 402 + TCGAAATCAAACCTGTACAC S|135|W S|135|L VMA16 Vacuolar Membrane Atpase 213.0 0 0 0 0 0.6530403761337502 P23968 0.04592390730977058 0.38870909810066223 39.68967522814074 40.0 1.0 no 5102 chrVIII_161263 15796 high_effect YHR026W 419 + CACTGGTTATTCTCTTTTCT T|141|S T|141|I VMA16 Vacuolar Membrane Atpase 213.0 0 0 0 0 -0.7246150344752946 P23968 0.33132362365722656 0.09982117265462877 47.09693892810453 35.0 1.0 no 5103 chrVIII_180430 15804 essential YHR036W 85 + ACCTAAGTATATCTAAGCAG L|30|V silent|CTA>TTA|L|30 D|29|E silent|GAC>GAT|D|29 BRL1 BRr6 Like protein 471.0 0 0 0 0 0.1316399079401909 P38770 0.9512209892272948 0.9532920122146606 0.0 0.38534015417099 40.5221477576726 35.0 1.0 no 5104 chrVIII_180509 15807 essential YHR036W 164 + ATCACCTCTGCGAAATACAT S|56|* S|56|L P|57|A P|57|S BRL1 BRr6 Like protein 471.0 1 Series([], Name: modification, dtype: object) 0 0 0 -1.1863206037963487 P38770 0.9298099875450134 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 44.66401411848256 40.0 1.0 no 5105 chrVIII_180685r 15811 essential YHR036W 343 - TTGCTTTTGTCTTTCTTCTG K|120|N silent|AAG>AAA|K|120 BRL1 BRr6 Like protein 471.0 0 0 0 0 0.8290454887650018 P38770 0.9355990290641784 0.3866924047470093 47.76676331928661 35.0 1.0 no 5106 chrVIII_180687r 15812 essential YHR036W 345 - TCTTGCTTTTGTCTTTCTTC E|122|Q E|122|K K|120|N silent|AAG>AAA|K|120 BRL1 BRr6 Like protein 471.0 0 0 0 0 0.5817310519253727 P38770 0.956179976463318 0.9475290179252625 0.9355990290641784 0.2309706658124924 0.09720692038536073 0.3866924047470093 48.991240687726076 35.0 1.0 no 5107 chrVIII_180722r 15813 essential YHR036W 380 - CCTCTTCTACACTTTGGTCT E|133|Q E|133|K E|133|D silent|GAG>GAA|E|133 BRL1 BRr6 Like protein 471.0 0 1 0 0 0.7492914379322047 P38770 0.956179976463318 0.9475290179252625 0.94931298494339 0.1788763552904129 0.21632814407348636 0.3974391222000122 53.062426518524326 45.0 1.0 no 5108 chrVIII_180722 15814 essential YHR036W 377 + CCAAGACCAAAGTGTAGAAG Q|127|E Q|127|* D|128|E silent|GAC>GAT|D|128 BRL1 BRr6 Like protein 471.0 0 1 0 0 -0.4653073683421619 P38770 0.9590039849281312 0.9532920122146606 1.0 1.0 41.30008703038681 45.0 1.0 no 5109 chrVIII_180728r 15815 essential YHR036W 386 - TCTCGACCTCTTCTACACTT E|135|Q E|135|K E|135|D silent|GAG>GAA|E|135 BRL1 BRr6 Like protein 471.0 0 1 0 0 0.8185030294839901 P38770 0.956179976463318 0.9475290179252625 0.94931298494339 0.43820467591285706 0.6473944187164307 0.6587409973144531 51.35158861062689 45.0 1.0 no 5110 chrVIII_180764 15816 essential YHR036W 419 + GCATCGTTCAACTGTCATAA H|141|D H|141|Y R|142|G R|142|C BRL1 BRr6 Like protein 471.0 0 1 0 0 0.5895749427655596 P38770 0.9473130106925964 0.9489949941635132 0.8994590044021606 0.8926740288734436 0.6550533771514893 0.05739438533782959 0.19122089445590973 0.026735831052064896 44.95795386894422 40.0 1.0 no 5111 chrVIII_180862r 15821 essential YHR036W 520 - ACTTTCATTGTCATCTTGAT S|180|T S|180|N E|179|Q E|179|K BRL1 BRr6 Like protein 471.0 0 0 0 0 -0.1277241894425946 P38770 0.9512869715690612 0.9536849856376648 0.956179976463318 0.9475290179252625 0.4041468799114227 0.2959791421890259 0.4014664888381958 0.4866812527179718 43.569852280332384 30.0 1.0 no 5112 chrVIII_181067 15827 essential YHR036W 722 + CAACTACTTCTATTCAGATA N|242|K silent|AAC>AAT|N|242 Y|243|* silent|TAC>TAT|Y|243 BRL1 BRr6 Like protein 471.0 0 0 0 0 -1.1206302742981382 P38770 0.9439849853515624 0.09450557082891464 38.657790178261905 30.0 1.0 no 5113 chrVIII_181119r 15829 essential YHR036W 777 - TCATCTATTTTATTGTGATT E|266|Q E|266|K D|265|H D|265|N BRL1 BRr6 Like protein 471.0 0 0 0 0 0.5078699765991818 P38770 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.2526315748691559 0.2887375056743622 0.23827752470970154 0.469717264175415 37.83276694201305 20.0 1.0 no 5114 chrVIII_188059r 15839 essential YHR040W 138 - TCACTCGATATATACTCCTT S|52|T S|52|N E|53|Q E|53|K BCD1 Box C/D snoRNA accumulation 366.0 0 0 0 0 -0.5901727512641282 P38772 0.2149047404527664 0.5532475113868713 0.31171914935112 0.2796802222728729 44.716162159933155 35.0 1.0 no 5115 chrVIII_188232r 15845 essential YHR040W 311 - TCTTCTTGAAATTAGAGTTG K|110|N silent|AAG>AAA|K|110 K|109|N silent|AAG>AAA|K|109 BCD1 Box C/D snoRNA accumulation 366.0 0 0 0 0 0.8726220156774562 P38772 0.5394954681396484 0.2078520953655243 37.08679864458748 30.0 1.0 no 5116 chrVIII_188322 15850 essential YHR040W 398 + GAACTGTTTGATGCTACCCA N|134|K silent|AAC>AAT|N|134 BCD1 Box C/D snoRNA accumulation 366.0 0 0 0 0 -0.8136688501064766 P38772 0.2446306049823761 49.624692455752104 45.0 1.0 no 5117 chrVIII_188394r 15857 essential YHR040W 473 - ACTCCACGCTCCATACAAAT E|164|Q E|164|K E|164|D silent|GAG>GAA|E|164 BCD1 Box C/D snoRNA accumulation 366.0 0 0 0 0 0.15564028203802122 P38772 0.03514083102345466 0.035252388566732414 0.08444702625274657 48.68638319663523 45.0 1.0 no 5118 chrVIII_188428r 15859 essential YHR040W 507 - TTCTCACCCTTTTCCTGCAT E|175|D silent|GAG>GAA|E|175 E|175|Q E|175|K BCD1 Box C/D snoRNA accumulation 366.0 0 0 0 0 0.5083534650209707 P38772 0.6152495741844177 0.5775365233421326 0.8960472345352173 57.118488050757605 45.0 1.0 no 5119 chrVIII_188481 15860 essential YHR040W 557 + TATCAAAGAGACAGACTTTT I|187|M silent|ATC>ATT|I|187 BCD1 Box C/D snoRNA accumulation 366.0 0 0 0 0 1.4302081241289393 P38772 0.13830110430717468 36.58514789557751 30.0 1.0 no 5120 chrVIII_188600r 15865 essential YHR040W 679 - GATCTGTGTTCTTTCCTCTT Q|232|H silent|CAG>CAA|Q|232 BCD1 Box C/D snoRNA accumulation 366.0 0 0 0 0 0.6306582999040943 P38772 0.15714146196842196 52.43832261804243 40.0 1.0 no 5121 chrVIII_190764 15878 essential YHR042W 221 + TTACGCCAAAAAGTTTTCCA Y|75|* silent|TAC>TAT|Y|75 A|76|G A|76|V NCP1 NADP-Cytochrome P450 reductase 691.0 0 0 0 0 -1.2290727366327292 P16603 0.9484469890594482 0.9504740238189696 0.04480137303471565 0.022379364818334583 1.8830000162124636 5.168000221252441 43.025170528193094 35.0 1.0 no 5122 chrVIII_190757r 15879 essential YHR042W 217 - AAACTTTTTGGCGTAATCCT K|78|N silent|AAG>AAA|K|78 NCP1 NADP-Cytochrome P450 reductase 691.0 0 0 0 0 0.6849444041309587 P16603 0.9355990290641784 0.019884448498487476 43.90254357898903 35.0 1.0 no 5123 chrVIII_190769r 15880 essential YHR042W 229 - CAGCTCCTTGGAAAACTTTT E|82|D silent|GAG>GAA|E|82 E|82|Q E|82|K NCP1 NADP-Cytochrome P450 reductase 691.0 0 0 0 0 0.6553037324005613 P16603 0.94931298494339 0.956179976463318 0.9475290179252625 0.03904656320810318 0.02122035808861256 0.1093449741601944 0.7401999831199646 0.46279999613761896 -0.015599999576807022 45.03756371494461 40.0 1.0 no 5124 chrVIII_190796r 15882 essential YHR042W 256 - CATCACGTTTAGGTTGAACT silent|GTG>GTC|V|91 silent|GTG>GTA|V|91 V|91|L V|91|M NCP1 NADP-Cytochrome P450 reductase 691.0 0 0 0 0 0.6814806640569089 P16603 0.9539830088615416 0.9587630033493042 0.14949198067188266 0.0393875315785408 0.7397999763488771 2.161600112915039 44.192441532260254 40.0 1.0 no 5125 chrVIII_190806r 15883 essential YHR042W 266 - CATCTGCGCACATCACGTTT D|95|H D|95|N A|94|P A|94|T NCP1 NADP-Cytochrome P450 reductase 691.0 0 0 0 0 -0.0964626831584845 P16603 0.9486550092697144 0.956179976463318 0.9573720097541808 0.9523990154266356 0.008332259953022003 0.04317393526434898 0.04514745250344277 0.032153818756341934 -1.111799955368042 -0.9742000102996826 4.82420015335083 1.8614000082015991 3.0455799102783203 1.850780010223389 51.6999793071301 50.0 1.0 no 5126 chrVIII_190876 15884 essential YHR042W 333 + TCGATTTTTATCTCTACATA S|112|W S|112|L NCP1 NADP-Cytochrome P450 reductase 691.0 0 0 0 0 0.3154557960559397 P16603 0.9288619756698608 0.9298099875450134 0.04624791070818901 0.8056330680847168 23.14459991455078 5.7189998626708975 39.271676914399336 25.0 1.0 no 5127 chrVIII_191005 15887 essential YHR042W 462 + TCTACTTATGAATTCTTTAA S|155|C S|155|F T|156|S T|156|I NCP1 NADP-Cytochrome P450 reductase 691.0 0 0 0 0 0.38167265693833663 P16603 0.945252001285553 0.9294660091400146 0.9491789937019348 0.9472420215606691 0.01447239797562361 0.009221657179296015 0.0 0.0 -0.2248000055551529 -0.8069999814033508 0.02580000087618828 -0.5058000087738037 34.60017537303247 20.0 1.0 no 5128 chrVIII_191147r 15893 essential YHR042W 607 - GTCTTTCAAAACCTCCAGGA D|209|H D|209|N L|207|F silent|TTG>TTA|L|207 NCP1 NADP-Cytochrome P450 reductase 691.0 0 0 0 0 0.4550732740635259 P16603 0.9486550092697144 0.956179976463318 0.9587849974632264 0.08928386121988298 0.5194023251533508 0.020051177591085437 0.0284000001847744 -0.328000009059906 6.446800231933594 48.61791583630992 45.0 1.0 no 5129 chrVIII_191151r 15894 essential YHR042W 611 - GTTCGTCTTTCAAAACCTCC E|210|Q E|210|K D|209|H D|209|N NCP1 NADP-Cytochrome P450 reductase 691.0 0 0 0 0 0.6916256541191033 P16603 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.5609593391418457 0.9169989824295044 0.08928386121988298 0.5194023251533508 -0.5644000172615051 -0.5382000207901001 0.0284000001847744 -0.328000009059906 48.631199122129885 45.0 1.0 no 5130 chrVIII_191316r 15900 essential YHR042W 776 - ACAAATCGAAGGGACCCAAT L|265|F silent|TTG>TTA|L|265 D|264|H D|264|N NCP1 NADP-Cytochrome P450 reductase 691.0 0 0 0 0 0.11853220757613768 P16603 0.9587849974632264 0.9486550092697144 0.956179976463318 0.18557147681713104 0.3730674982070923 1.0 0.6011999845504761 2.0820000171661377 0.7454000115394592 0.1143599972128868 43.928923928174235 45.0 1.0 no 5131 chrVIII_191477r 15910 essential YHR042W 937 - TTCGACCTTTTCCAATGGGT E|319|Q E|319|K V|318|L V|318|I NCP1 NADP-Cytochrome P450 reductase 691.0 0 0 0 0 -1.0324200271487398 P16603 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.2588634788990021 0.21618054807186127 0.027905484661459926 0.14749868214130402 0.04899999871850014 0.02199999988079071 0.2770000100135803 0.219200000166893 51.468343147700644 45.0 1.0 no 5132 chrVIII_191482r 15911 essential YHR042W 942 - AACTGTTCGACCTTTTCCAA Q|320|H silent|CAG>CAA|Q|320 NCP1 NADP-Cytochrome P450 reductase 691.0 0 0 0 0 0.18224635417721413 P16603 0.9570760130882264 0.1878088116645813 1.0496000051498413 47.50746228722539 40.0 1.0 no 5133 chrVIII_191502 15912 essential YHR042W 959 + GTTCTTATCCATATTCAACC F|321|L silent|TTC>TTT|F|321 NCP1 NADP-Cytochrome P450 reductase 691.0 0 0 0 0 -0.3067613803712731 P16603 0.9387490153312684 0.23792099952697754 2.146399974822998 45.43817955071818 35.0 1.0 no 5134 chrVIII_191611 15920 essential YHR042W 1068 + AAACACTATTTGGAAATTAC H|358|D H|358|Y H|358|Q silent|CAC>CAT|H|358 NCP1 NADP-Cytochrome P450 reductase 691.0 0 0 0 0 -0.714673116527786 P16603 0.9473130106925964 0.9489949941635132 0.9588389992713928 0.18284407258033752 1.0 0.08130116760730742 1.4390000104904177 -1.8971999883651731 1.3874000310897827 32.032887786696165 25.0 1.0 no 5135 chrVIII_191676r 15921 essential YHR042W 1136 - TTTCCTTGACGTCAGCGTTG E|385|Q E|385|K K|384|N silent|AAG>AAA|K|384 NCP1 NADP-Cytochrome P450 reductase 691.0 0 0 0 0 -0.9751823968335313 P16603 0.956179976463318 0.9475290179252625 0.9355990290641784 0.5647925734519958 0.8735787272453308 0.012607302516698836 -0.08860000222921371 -0.4555999934673309 1.3555999994277954 52.037575778161965 50.0 1.0 no 5136 chrVIII_191773 15923 essential YHR042W 1230 + GCTCTGAAATATTTGTCTGA L|412|V silent|CTG>TTG|L|412 A|411|G A|411|V NCP1 NADP-Cytochrome P450 reductase 691.0 0 1 0 0 -0.032852407574934565 P16603 0.9512209892272948 0.9484469890594482 0.9504740238189696 0.02127762883901596 0.037396516650915146 1.0 2.6733999252319336 2.0739998817443848 2.042200088500977 42.09925721064093 35.0 1.0 no 5137 chrVIII_191901 15925 essential YHR042W 1358 + CGTCCATGTCACCTCCATTG silent|GTC>GTG|V|454 silent|GTC>GTT|V|454 H|455|D H|455|Y NCP1 NADP-Cytochrome P450 reductase 691.0 0 0 0 0 0.3751505154177622 P16603 0.9473130106925964 0.9489949941635132 0.3073011636734009 0.1198774427175522 3.1496000289916988 1.9221999645233157 56.15044777036882 55.00000000000001 1.0 no 5138 chrVIII_191932r 15927 essential YHR042W 1392 - GCATCAGGCAATTCTGGGTT A|471|P A|471|T D|470|H D|470|N NCP1 NADP-Cytochrome P450 reductase 691.0 0 0 0 0 -0.9397072161982848 P16603 0.9573720097541808 0.9523990154266356 0.9486550092697144 0.956179976463318 0.06562110781669618 0.09307318925857544 0.2407403439283371 0.5383561253547668 3.0741999149322514 2.781399965286255 0.21660000085830688 0.2360000014305115 3.2488200664520264 1.872480034828186 53.398450832754975 50.0 1.0 no 5139 chrVIII_192040 15929 essential YHR042W 1497 + CCTGTTCACTACGATTTAAA P|500|R P|500|L H|502|D H|502|Y NCP1 NADP-Cytochrome P450 reductase 691.0 0 0 0 0 -0.9233547327089444 P16603 0.9432820081710817 0.9430609941482544 0.9473130106925964 0.9489949941635132 0.23364880681037906 0.1756456345319748 0.2168940156698227 0.10430429875850676 3.524199962615967 3.6054000854492183 2.4570000171661377 -0.3571999967098236 1.74344003200531 -0.5123599767684937 41.675767020722326 35.0 1.0 no 5140 chrVIII_219214r 15931 essential YHR058C 648 + AACGGGAACAACGCTGGAGG N|217|K silent|AAC>AAT|N|217 MED6 MEDiator complex 295.0 0 1 0 0 -2.5800646368164952 P38782 0.9224518537521362 46.96415413765328 60.0 0.0 yes 5141 chrVIII_219231r 15938 essential YHR058C 631 + CTGCAACGGCTGCCACCAAC A|212|G A|212|V T|213|R T|213|M MED6 MEDiator complex 295.0 0 1 0 0 0.310305656172965 P38782 0.6054096221923828 0.2599114179611206 0.5299236774444579 0.11446766555309296 56.016896474931 65.0 0.0 no 5142 chrVIII_219273 15942 essential YHR058C 592 - TACTTTATAGTGTACTCCTT V|204|L V|204|I MED6 MEDiator complex 295.0 0 0 0 0 -0.2794788967813072 P38782 0.38482120633125305 0.2383820861577988 44.03866536745322 30.0 0.0 no 5143 chrVIII_219329r 15943 essential YHR058C 533 + CTACCATCTAAATAGCACAT Y|179|* silent|TAC>TAT|Y|179 H|180|D H|180|Y MED6 MEDiator complex 295.0 0 0 0 0 -0.1768083803277722 P38782 0.3969895243644713 0.21161431074142456 0.3740000128746033 -0.2800000011920929 41.65858073744079 35.0 0.0 no 5144 chrVIII_219326 15944 essential YHR058C 539 - TCTCCAATGTGCTATTTAGA E|186|Q E|186|K E|186|D silent|GAG>GAA|E|186 MED6 MEDiator complex 295.0 0 0 0 0 1.4367395636267566 P38782 0.5360530018806458 0.8782315850257874 0.5908688902854919 45.332514303657256 35.0 0.0 no 5145 chrVIII_219571 15950 essential YHR058C 294 - TCCTCCAGTTGCATATACAT E|104|D silent|GAG>GAA|E|104 E|105|Q E|105|K MED6 MEDiator complex 295.0 0 0 0 0 -0.8383100371753311 P38782 0.2634248733520508 0.761613130569458 1.0 50.59520260699782 40.0 0.0 no 5146 chrVIII_219612 15951 essential YHR058C 253 - TCTTCTTGCCGGATCCACAT R|91|T R|91|K R|90|T R|90|K MED6 MEDiator complex 295.0 0 0 0 0 -0.7614576354296987 P38782 3.486000061035156 -0.19480000436306 55.36063624207037 50.0 0.0 no 5147 chrVIII_219654 15952 essential YHR058C 211 - TCCATTCTTCCCATCTGGTA G|77|R G|77|R G|77|A G|77|E MED6 MEDiator complex 295.0 0 0 0 0 -0.4425655548018725 P38782 56.24185762187602 45.0 0.0 no 5148 chrVIII_219691 15956 essential YHR058C 174 - GTCATATTCACGGCAGCATT M|64|I M|64|I MED6 MEDiator complex 295.0 0 0 0 0 0.131891176989528 P38782 0.8919033408164978 0.8919033408164978 0.42719998955726624 0.42719998955726624 50.48260389626239 45.0 0.0 no 5149 chrVIII_219823 15959 essential YHR058C 42 - CCAAAAACTTGAATCCATTC G|21|R G|21|S MED6 MEDiator complex 295.0 0 0 0 0 -0.6209271493130637 P38782 0.0 0.0 38.66423725805004 35.0 0.0 no 5150 chrVIII_220810r 15961 high_effect YHR060W 88 - CTTCTGCAACTGCTCTAAGG Q|35|H silent|CAG>CAA|Q|35 L|34|F silent|TTG>TTA|L|34 VMA22 Vacuolar Membrane Atpase 181.0 0 0 0 0 -0.8923882391990934 P38784 0.9570760130882264 0.9587849974632264 0.02118677459657192 0.0 48.51003379115497 50.0 1.0 no 5151 chrVIII_220884 15966 high_effect YHR060W 159 + GACTCATTACGAGGAAACTA D|54|E silent|GAC>GAT|D|54 S|55|* S|55|L VMA22 Vacuolar Membrane Atpase 181.0 0 0 0 0 -0.34810215120748805 P38784 0.9532920122146606 0.9298099875450134 0.0 0.023349607363343242 40.183094064138174 40.0 1.0 no 5152 chrVIII_220969r 15968 high_effect YHR060W 247 - GACGATTTCGACAACTACCT V|89|L V|89|I VMA22 Vacuolar Membrane Atpase 181.0 0 0 0 0 -0.13652955535254094 P38784 0.9539830088615416 0.9574310183525084 0.5734115839004517 0.575513482093811 45.25708124387813 45.0 1.0 no 5153 chrVIII_221879 15972 no_effect YHR061C 580 - CATCGTTGTAGCTATTGTGG silent|ACG>ACC|T|199 silent|ACG>ACA|T|199 0 0 0 0 0.3481915761884657 P38785 47.78384502885416 45.0 0.0 no 5154 chrVIII_222104 15974 no_effect YHR061C 355 - ACTTGACTGTTTTGCGGTTT S|125|T S|125|N Q|123|H silent|CAG>CAA|Q|123 0 0 0 0 -0.29205118165166083 P38785 0.9669449925422668 0.9709960222244264 0.985951006412506 0.6054365038871765 0.41170406341552734 0.16946057975292206 48.95265615436621 40.0 0.0 no 5155 chrVIII_223088 15986 essential YHR062C 651 - GCCTTCGAACACCTATCGCT K|223|N silent|AAG>AAA|K|223 A|224|P A|224|T RPP1 Ribonuclease P Protein 293.0 0 0 0 0 -0.3562338807788244 P38786 0.4973520636558533 0.22689467668533325 0.4376853108406067 54.85303194238327 55.00000000000001 0.0 no 5156 chrVIII_223115r 15988 essential YHR062C 621 + ACAAGTCTAATCAAGAATTT T|208|R T|208|I L|210|V silent|CTA>TTA|L|210 RPP1 Ribonuclease P Protein 293.0 0 0 0 0 -0.9632995267521308 P38786 0.3595066070556641 0.4431644976139069 0.5408104062080383 34.14389602933653 25.0 0.0 no 5157 chrVIII_223317 15994 essential YHR062C 422 - TGCATATGCTTTTATGCTTA C|147|S C|147|Y RPP1 Ribonuclease P Protein 293.0 0 0 0 0 0.9064586471071008 P38786 0.6651859879493713 0.1321258693933487 44.48693222964221 30.0 0.0 no 5158 chrVIII_223357r 15995 essential YHR062C 379 + ACTTGTTGACCTTTCAGTAC D|127|E silent|GAC>GAT|D|127 RPP1 Ribonuclease P Protein 293.0 0 0 0 0 1.1521308237011274 P38786 0.0 47.316662239162 40.0 0.0 no 5159 chrVIII_223386r 15997 essential YHR062C 350 + TACTTTATCAACTACCAATC T|118|S T|118|I RPP1 Ribonuclease P Protein 293.0 0 0 0 0 0.2620507224014242 P38786 0.4976304173469544 0.4832904636859894 38.617550525695435 30.0 0.0 no 5160 chrVIII_227942 16006 essential YHR065C 1076 - GATCCAAAGATCCCATTCTC D|365|H D|365|N L|364|F silent|TTG>TTA|L|364 RRP3 Ribosomal RNA Processing 501.0 0 0 0 0 0.11535618420799265 P38712 0.028433723375201225 1.0 0.04707348719239235 48.705991723817256 45.0 0.0 no 5161 chrVIII_228021 16008 essential YHR065C 997 - TCCTGACAACCTTTCCGCGT G|339|R G|339|R G|339|A G|339|E RRP3 Ribosomal RNA Processing 501.0 0 0 0 0 -0.9296200309981472 P38712 0.07140611112117767 0.07140611112117767 0.16416186094284058 0.05595533922314644 56.337412107148 55.00000000000001 0.0 no 5162 chrVIII_228027 16010 essential YHR065C 991 - CAACCTTTCCGCGTTGGCCT R|336|S silent|AGG>AGA|R|336 R|336|T R|336|K RRP3 Ribosomal RNA Processing 501.0 0 0 0 0 0.20590358350565488 P38712 0.05545780062675476 0.06869211047887802 0.6230117678642273 59.58457412467585 60.0 0.0 no 5163 chrVIII_228134r 16015 essential YHR065C 881 + TACATTAGTGCAAACACTGA T|295|R T|295|I RRP3 Ribosomal RNA Processing 501.0 0 0 0 0 0.9457318598414554 P38712 0.08748903125524521 0.0262681283056736 40.00359687177422 35.0 0.0 no 5164 chrVIII_228509r 16022 essential YHR065C 506 + TGACTCATTAGGATCCTTAA D|170|E silent|GAC>GAT|D|170 S|171|* S|171|L RRP3 Ribosomal RNA Processing 501.0 0 0 0 0 0.7361912309623186 P38712 1.0 0.009847951121628284 43.187727372328474 35.0 0.0 no 5165 chrVIII_228508r 16023 essential YHR065C 507 + GACTCATTAGGATCCTTAAT D|170|E silent|GAC>GAT|D|170 S|171|* S|171|L RRP3 Ribosomal RNA Processing 501.0 0 0 0 0 -0.920549223796486 P38712 1.0 0.009847951121628284 43.17967624668722 35.0 0.0 no 5166 chrVIII_228612r 16026 essential YHR065C 403 + TTGCTATTCCCATTTTGAAT A|136|G A|136|V RRP3 Ribosomal RNA Processing 501.0 0 0 0 0 1.0174311424724642 P38712 0.1095735728740692 0.16880740225315094 45.08110662798129 30.0 0.0 no 5167 chrVIII_228809 16032 essential YHR065C 209 - CTTCATTAGTATTTTCATTT E|76|Q E|76|K RRP3 Ribosomal RNA Processing 501.0 0 0 0 0 0.7408937273564321 P38712 0.5340823531150818 0.8259095549583435 -0.909875988960266 -0.4799219965934754 38.485670479306066 20.0 0.0 no 5168 chrVIII_232244r 16035 essential YHR068W 114 - GCTCTCATATTAGTGGCTTC R|44|T R|44|K A|45|P A|45|T DYS1 DeoxyhYpusine Synthase 387.0 0 0 0 0 0.061855794177428765 P38791 0.4303618967533112 0.26139378547668457 0.11190968006849288 0.21406634151935575 -1.7796000242233276 0.14880000054836273 51.36748326204964 45.0 1.0 no 5169 chrVIII_232423 16037 essential YHR068W 290 + CCAAAAGACTACTATCTTCA Q|98|E Q|98|* DYS1 DeoxyhYpusine Synthase 387.0 0 0 0 0 0.42028361886414856 P38791 1.0 40.095767686446145 35.0 1.0 no 5170 chrVIII_232451 16039 essential YHR068W 318 + ACTTCTAACTTGATCAGTTC T|107|S T|107|I S|108|C S|108|F DYS1 DeoxyhYpusine Synthase 387.0 0 0 0 0 -0.5461260986798729 P38791 0.013206634670495987 0.001813102513551712 0.0 0.0 42.16981547737237 35.0 1.0 no 5171 chrVIII_232470r 16040 essential YHR068W 340 - ACGTAAAGTTTCACGTACAC R|120|P R|120|H DYS1 DeoxyhYpusine Synthase 387.0 0 0 0 0 -1.6051151443068468 P38791 0.06617724150419235 0.11862915009260178 41.24046643452068 40.0 1.0 no 5172 chrVIII_232520 16042 essential YHR068W 387 + GCTGTCGTTACTTCTGCTGG A|130|G A|130|V silent|GTC>GTG|V|131 silent|GTC>GTT|V|131 DYS1 DeoxyhYpusine Synthase 387.0 0 0 0 0 -0.4607687002977565 P38791 0.3585706353187561 1.0 55.507879354932925 55.00000000000001 1.0 no 5173 chrVIII_232655r 16043 essential YHR068W 525 - AACTTACAGTAGTTATCATT K|181|N silent|AAG>AAA|K|181 C|180|S C|180|Y DYS1 DeoxyhYpusine Synthase 387.0 0 0 0 0 -1.0002800317704277 P38791 0.38954126834869385 0.022898154333233837 0.021107330918312076 0.2440000027418137 -0.11760000139474867 37.958096006216 25.0 1.0 no 5174 chrVIII_232694r 16046 essential YHR068W 564 - TCCAACATCTTATCCAAAAT L|194|F silent|TTG>TTA|L|194 E|195|Q E|195|K DYS1 DeoxyhYpusine Synthase 387.0 0 0 0 0 0.7220342264861176 P38791 0.1960198134183884 0.5400753021240234 0.8204304575920105 3.259000062942505 40.10902901389511 30.0 1.0 no 5175 chrVIII_232796r 16049 essential YHR068W 666 - AAACGATCTATCATCTTAGA R|228|P R|228|H DYS1 DeoxyhYpusine Synthase 387.0 0 1 0 0 0.06387318494129879 P38791 0.01635170914232731 0.11334482580423355 37.593557793654156 30.0 1.0 no 5176 chrVIII_232799 16050 essential YHR068W 666 + TCTAAGATGATAGATCGTTT S|223|C S|223|F DYS1 DeoxyhYpusine Synthase 387.0 0 0 0 0 -1.2289337084253813 P38791 0.0027553390245884657 0.001796950469724834 38.329035550296 30.0 1.0 no 5177 chrVIII_232836 16051 essential YHR068W 703 + ACGAATCCTCCGTATTGTAC D|235|E silent|GAC>GAT|D|235 S|237|C S|237|F DYS1 DeoxyhYpusine Synthase 387.0 0 1 0 0 0.8210264666801564 P38791 0.02039358764886856 0.04222013428807258 0.03938157483935356 47.74551327842761 45.0 1.0 no 5178 chrVIII_232955 16053 essential YHR068W 822 + CAACTAAGAGTTGACATTGT L|276|V silent|CTA>TTA|L|276 DYS1 DeoxyhYpusine Synthase 387.0 0 0 0 0 -0.2918405625247542 P38791 0.09906085580587387 2.1933999061584477 39.07764210638493 35.0 1.0 no 5179 chrVIII_233834 16055 essential YHR069C 805 - CTCTTCTTCCAGTCTTGTTA E|275|Q E|275|K E|274|Q E|274|K RRP4 Ribosomal RNA Processing 359.0 0 0 0 0 -0.982523586077884 P38792 0.5876129269599915 0.7532429695129395 0.1045651063323021 0.09042584151029588 0.06492000073194504 -0.010940000414848328 -0.7584000229835509 -0.8921999931335449 0.17820000648498535 -0.2897999882698059 52.04086017837727 40.0 0.0 no 5180 chrVIII_233963r 16062 essential YHR069C 673 + TCGGAGTCAATGGTTACATA silent|CTC>CTG|L|225 silent|CTC>CTT|L|225 RRP4 Ribosomal RNA Processing 359.0 0 0 0 0 -0.02242083965582373 P38792 44.228918260750284 40.0 0.0 no 5181 chrVIII_233973r 16064 essential YHR069C 663 + ACCGTAGTTCTCGGAGTCAA silent|ACC>ACG|T|222 silent|ACC>ACT|T|222 T|222|S T|222|I RRP4 Ribosomal RNA Processing 359.0 0 0 0 0 -0.7712966604241029 P38792 0.16576455533504486 0.006262853741645813 1.5816600322723389 0.9001200199127197 51.599474396173036 50.0 0.0 no 5182 chrVIII_234031 16066 essential YHR069C 608 - CTCTCACTATTAATGAACTC R|209|T R|209|K silent|GTG>GTC|V|208 silent|GTG>GTA|V|208 RRP4 Ribosomal RNA Processing 359.0 0 0 0 0 0.7012953026584622 P38792 0.0065317368134856215 0.11718846112489699 2.7690200805664062 2.045939922332764 38.92632417583451 35.0 0.0 no 5183 chrVIII_234222r 16069 essential YHR069C 414 + GGCTCTGTGAATTTACCGGG silent|GGC>GGG|G|139 silent|GGC>GGT|G|139 S|140|C S|140|F RRP4 Ribosomal RNA Processing 359.0 0 0 0 1 -0.8894397336721873 P38792 0.00534675782546401 0.002167881233617664 0.7849000096321106 -0.6553400158882141 52.15751091884068 55.00000000000001 0.0 no 5184 chrVIII_234317r 16073 essential YHR069C 319 + AAACTGGTGATCACGTCGTA T|108|S T|108|I RRP4 Ribosomal RNA Processing 359.0 0 0 0 0 -0.04021534197588028 P38792 0.00918866042047739 0.8054526448249817 0.8575999736785889 -0.6705600023269653 0.20679999887943268 -0.9684000015258788 45.216856413014796 45.0 0.0 no 5185 chrVIII_234624r 16084 essential YHR069C 12 + ATCACAATTACCAAGCGGAA I|5|M silent|ATC>ATT|I|5 T|6|R T|6|I RRP4 Ribosomal RNA Processing 359.0 0 1 0 0 0.307495117819379 P38792 0.1627800017595291 1.4031800031661987 1.4693399667739868 -0.1242000013589859 -0.3188000023365021 0.11599999666213988 -0.4117400050163269 4.70704984664917 1.1229699850082395 42.776134668928755 40.0 0.0 no 5186 chrVIII_234965r 16088 essential YHR070W 87 - TCTCGCATTTGGCGATTCAC R|35|P R|35|Q E|36|Q E|36|K TRM5 tRNA Methyltransferase 499.0 0 0 0 0 0.9098695983640668 P38793 0.10452503710985184 0.2712602913379669 0.5543909072875977 0.86491858959198 51.09828388183973 50.0 1.0 no 5187 chrVIII_234975 16089 essential YHR070W 94 + GCCAAATGCGAGAATTGGAT Q|33|E Q|33|* silent|CGC>CGG|R|32 silent|CGC>CGT|R|32 TRM5 tRNA Methyltransferase 499.0 0 0 0 0 -0.8512808109210434 P38793 1.0 44.661870948885614 45.0 1.0 no 5188 chrVIII_235074 16093 essential YHR070W 193 + ACTTCAAAAATTGCATCTTG N|65|K silent|AAC>AAT|N|65 F|66|L silent|TTC>TTT|F|66 TRM5 tRNA Methyltransferase 499.0 0 1 0 0 -0.9390240439045716 P38793 0.9425097703933716 0.6582084894180298 36.740280379990786 30.0 1.0 no 5189 chrVIII_235075 16094 essential YHR070W 194 + CTTCAAAAATTGCATCTTGA F|66|L silent|TTC>TTT|F|66 TRM5 tRNA Methyltransferase 499.0 0 1 0 0 -0.8142838369825611 P38793 0.6582084894180298 37.47152549724558 30.0 1.0 no 5190 chrVIII_235202r 16098 essential YHR070W 324 - AGCAGCACACCTTTCGTGAC silent|CTG>CTC|L|114 silent|CTG>CTA|L|114 silent|GTG>GTC|V|113 silent|GTG>GTA|V|113 TRM5 tRNA Methyltransferase 499.0 0 0 0 0 0.950723805028999 P38793 54.11611197603838 55.00000000000001 1.0 no 5191 chrVIII_235379r 16104 essential YHR070W 501 - ACCTCTTCCAGGAATTGCTC E|173|D silent|GAG>GAA|E|173 V|174|L V|174|I TRM5 tRNA Methyltransferase 499.0 0 0 0 0 -0.15575990573108953 P38793 0.3631877303123474 0.23871712386608124 0.5265424847602844 53.56572538512489 50.0 1.0 no 5192 chrVIII_235403 16105 essential YHR070W 522 + CCAACGGGTTTTACAATCAC P|175|R P|175|L T|176|R T|176|M TRM5 tRNA Methyltransferase 499.0 0 0 0 0 -1.3599645975232793 P38793 0.0 0.0 0.031326957046985626 0.016452202573418617 45.02910775905508 45.0 1.0 no 5193 chrVIII_235536 16113 essential YHR070W 655 + GCTCCATTGCCACACAGTTC S|220|C S|220|F S|219|R silent|AGC>AGT|S|219 TRM5 tRNA Methyltransferase 499.0 0 0 0 0 0.06483764364027345 P38793 0.015385229140520098 0.00874966196715832 0.015596531331539152 57.67393055043697 55.00000000000001 1.0 no 5194 chrVIII_235630 16116 essential YHR070W 749 + TTTCAAATTCGACTTTAGCA F|251|L silent|TTC>TTT|F|251 TRM5 tRNA Methyltransferase 499.0 0 0 0 0 0.999605937608148 P38793 0.0 40.09565339701618 30.0 1.0 no 5195 chrVIII_235665r 16117 essential YHR070W 787 - TTCATGCTCTGTGTGCAATC E|269|Q E|269|K E|267|D silent|GAG>GAA|E|267 TRM5 tRNA Methyltransferase 499.0 0 0 0 0 -1.3461223832355722 P38793 0.11026480793952942 0.09701337665319444 0.0 49.85567363556925 45.0 1.0 no 5196 chrVIII_235865 16128 essential YHR070W 984 + GTCAAATCCTTCAACATGGA silent|GTC>GTG|V|329 silent|GTC>GTT|V|329 TRM5 tRNA Methyltransferase 499.0 0 0 0 0 0.9909351145748828 P38793 44.054552794784 40.0 1.0 no 5197 chrVIII_239269r 16136 essential YHR072W 174 - TTTCTTTCTGGATGAGGTTG R|64|T R|64|K ERG7 ERGosterol biosynthesis 731.0 0 0 0 0 0.78862086958214 P38604 0.932735025882721 0.955805003643036 0.5711695551872253 0.9620678424835204 46.02288297515304 40.0 1.0 no 5198 chrVIII_239315r 16139 essential YHR072W 220 - ACCATTATGACACGCATCGA G|80|R G|80|S G|80|A G|80|D ERG7 ERGosterol biosynthesis 731.0 0 0 0 0 -1.868435161830004 P38604 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.009324602782726288 0.06802444159984589 0.2825044691562653 0.010762440972030165 47.300223997736786 45.0 1.0 no 5199 chrVIII_239353 16140 essential YHR072W 255 + CTGCTTCAAGAGCCTGACTC L|87|V L|87|F Q|88|E Q|88|* ERG7 ERGosterol biosynthesis 731.0 0 0 0 0 -2.2959422186877165 P38604 0.9512209892272948 0.9587849974632264 0.9590039849281312 0.26436886191368103 0.02432618103921413 0.0 52.889851252688 55.00000000000001 1.0 yes 5200 chrVIII_239490 16144 essential YHR072W 392 + CATCGTCAATACAGCACATC I|132|M silent|ATC>ATT|I|132 silent|GTC>GTG|V|133 silent|GTC>GTT|V|133 ERG7 ERGosterol biosynthesis 731.0 0 0 0 0 0.18958178915772075 P38604 0.9598389863967896 0.013046297244727613 45.011251096339436 45.0 1.0 no 5201 chrVIII_239509r 16149 essential YHR072W 414 - AGACCCCAGCCACCATCAAC G|144|A G|144|D G|144|R G|144|S ERG7 ERGosterol biosynthesis 731.0 0 0 0 0 -0.44300371954417 P38604 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.0 0.0 0.0 0.0 58.30889016637826 60.0 1.0 no 5202 chrVIII_239586 16151 essential YHR072W 488 + ACGTTTATTGGGTCTACCCA R|164|G R|164|C ERG7 ERGosterol biosynthesis 731.0 0 0 0 0 -0.4685191667927902 P38604 0.8994590044021606 0.8926740288734436 0.0 0.0 52.58691581427763 45.0 1.0 no 5203 chrVIII_239607 16154 essential YHR072W 509 + GGACCACCCGGTTTGCGCCA D|171|E silent|GAC>GAT|D|171 H|172|D H|172|Y ERG7 ERGosterol biosynthesis 731.0 0 0 0 0 0.9523984087895684 P38604 0.9532920122146606 0.9473130106925964 0.9489949941635132 0.627210259437561 1.0 0.3832583725452423 64.5780985151399 70.0 1.0 no 5204 chrVIII_239624r 16158 essential YHR072W 529 - TAACAATGTGCTTCTTGCCT L|182|F silent|TTG>TTA|L|182 ERG7 ERGosterol biosynthesis 731.0 0 0 0 0 0.4258429549421688 P38604 0.9587849974632264 0.011004372499883177 47.95691029868335 40.0 1.0 no 5205 chrVIII_239670r 16165 essential YHR072W 575 - GCCAAATTTTTCCCCAGTGA W|198|S W|198|* W|198|C W|198|* ERG7 ERGosterol biosynthesis 731.0 0 0 0 0 -1.0638812737925458 P38604 0.8858469724655151 0.8858469724655151 0.0 0.0 53.098803941452616 45.0 1.0 no 5206 chrVIII_239696 16166 essential YHR072W 598 + GTGCACTAAACTTGTATAAA A|201|G A|201|V L|202|V silent|CTA>TTA|L|202 ERG7 ERGosterol biosynthesis 731.0 0 0 0 0 -0.7276048487861773 P38604 0.9484469890594482 0.9504740238189696 0.9512209892272948 0.002782200463116169 1.0 0.010549752041697502 36.669558914682504 30.0 1.0 no 5207 chrVIII_239697 16167 essential YHR072W 599 + TGCACTAAACTTGTATAAAT A|201|G A|201|V L|202|V silent|CTA>TTA|L|202 ERG7 ERGosterol biosynthesis 731.0 0 0 0 0 0.032963291594626964 P38604 0.9484469890594482 0.9504740238189696 0.9512209892272948 0.002782200463116169 1.0 0.010549752041697502 34.48333536315545 25.0 1.0 no 5208 chrVIII_240183 16180 essential YHR072W 1085 + GCGTCTCCAATATAGGTTCA R|363|G R|363|C L|364|V L|364|F ERG7 ERGosterol biosynthesis 731.0 0 0 0 0 -1.0825782238303132 P38604 0.8994590044021606 0.8926740288734436 0.9512209892272948 0.9587849974632264 0.29053160548210144 0.04082752391695976 0.09356825798749924 0.05147254467010498 50.606756783576834 45.0 1.0 no 5209 chrVIII_240223r 16186 essential YHR072W 1128 - CCCATAATGGTCATACCCTG M|382|I M|382|I G|383|R G|383|R ERG7 ERGosterol biosynthesis 731.0 0 0 0 0 -0.16002928379641074 P38604 0.9553959965705872 0.9553959965705872 0.941340982913971 0.941340982913971 0.1923091858625412 0.1923091858625412 0.0 0.0 52.18592426478107 50.0 1.0 no 5210 chrVIII_240319r 16190 essential YHR072W 1224 - ACAATTGTGTTATAGAATTC V|415|L V|415|I ERG7 ERGosterol biosynthesis 731.0 0 0 0 0 -0.08741156466957309 P38604 0.9539830088615416 0.9574310183525084 0.3736949563026428 0.22571240365505216 34.73923725806929 25.0 1.0 no 5211 chrVIII_240391r 16193 essential YHR072W 1296 - CTCTTATCCCTATAACTACC K|438|N silent|AAG>AAA|K|438 ERG7 ERGosterol biosynthesis 731.0 0 0 0 0 -0.7220145263093249 P38604 0.9355990290641784 0.35596203804016113 47.35501034375257 40.0 1.0 no 5212 chrVIII_240477 16194 essential YHR072W 1379 + AGCAATTAAAGCCATCATCA A|461|G A|461|V ERG7 ERGosterol biosynthesis 731.0 0 1 0 0 0.6334027614262712 P38604 0.9484469890594482 0.9504740238189696 0.8725130558013916 0.02834106981754303 42.9230164291842 35.0 1.0 no 5213 chrVIII_240531r 16195 essential YHR072W 1436 - AACGTTCACTGCTAATCATA R|485|P R|485|H E|484|Q E|484|K ERG7 ERGosterol biosynthesis 731.0 0 0 0 0 -0.30370381224960863 P38604 0.9099509716033936 0.9570810198783876 0.956179976463318 0.9475290179252625 0.007821534760296345 0.008654708042740822 0.6353520750999451 0.41970738768577576 41.94692234245122 35.0 1.0 no 5214 chrVIII_240589 16196 essential YHR072W 1491 + AACATCGGATCTTTTGAATA N|498|K silent|AAC>AAT|N|498 I|499|M silent|ATC>ATT|I|499 ERG7 ERGosterol biosynthesis 731.0 0 0 0 0 0.5624193906262028 P38604 0.9439849853515624 0.9598389863967896 0.006082288920879364 0.097528874874115 38.334912434546204 30.0 1.0 no 5215 chrVIII_240633 16197 essential YHR072W 1535 + AATCAAGGCCCCACTAGCAA I|513|M silent|ATC>ATT|I|513 ERG7 ERGosterol biosynthesis 731.0 0 0 0 0 0.7584697758170422 P38604 0.9598389863967896 0.12222994863986968 51.991767954201244 50.0 1.0 no 5216 chrVIII_240643r 16199 essential YHR072W 1548 - TTCAAGGTTTCCATTGCTAG L|522|F silent|TTG>TTA|L|522 ERG7 ERGosterol biosynthesis 731.0 0 0 0 0 -0.13055692212657674 P38604 0.9587849974632264 0.28084930777549744 47.23926219210552 40.0 1.0 no 5217 chrVIII_240716 16201 essential YHR072W 1618 + GTACTGATTCATCCGTTCTG T|541|S T|541|I ERG7 ERGosterol biosynthesis 731.0 0 0 0 0 0.03593436054295169 P38604 0.9491789937019348 0.9472420215606691 0.16415467858314514 0.0028512924909591675 49.001416044306325 45.0 1.0 no 5218 chrVIII_246215 16202 essential YHR074W 22 + CTACATGCAACTTGAATCAA T|9|R T|9|I QNS1 glutamine (Q) dependent Nad+ Synthetase 714.0 0 0 0 0 -0.3700754798440303 P38795 0.9476869702339172 0.9472420215606691 0.008332967758178711 0.05756748095154762 39.048719473803494 35.0 1.0 no 5219 chrVIII_246290r 16207 essential YHR074W 100 - TAACCTGGCACCCCTCTCTT R|39|S silent|AGG>AGA|R|39 R|39|T R|39|K QNS1 glutamine (Q) dependent Nad+ Synthetase 714.0 0 0 0 0 -0.2391338938025669 P38795 0.9087679982185364 0.932735025882721 0.955805003643036 0.7892568111419678 0.8988649249076843 1.0 59.67639742854192 55.00000000000001 1.0 no 5220 chrVIII_246305r 16208 essential YHR074W 115 - TTCTGGGCCGACACGTAACC E|45|Q E|45|K QNS1 glutamine (Q) dependent Nad+ Synthetase 714.0 0 0 0 0 -5.572726315929733 P38795 0.956179976463318 0.9475290179252625 0.005602199584245682 0.004334934521466494 54.29999454221832 60.0 1.0 yes 5221 chrVIII_246322r 16209 essential YHR074W 132 - TAGCCAGTTATTTCCAGTTC G|50|A G|50|D G|50|R G|50|S QNS1 glutamine (Q) dependent Nad+ Synthetase 714.0 0 0 0 0 0.5810224057273233 P38795 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.0 0.0 0.0 0.0 50.83563692378175 40.0 1.0 no 5222 chrVIII_246372 16210 essential YHR074W 179 + TGACGTTTGCCTTCATTCAT D|61|E silent|GAC>GAT|D|61 QNS1 glutamine (Q) dependent Nad+ Synthetase 714.0 0 0 0 0 0.6141285258326077 P38795 0.9532920122146606 0.0 49.567165986144225 40.0 1.0 no 5223 chrVIII_246500r 16213 essential YHR074W 310 - GAACAATATCTCACCATCCA L|109|F silent|TTG>TTA|L|109 QNS1 glutamine (Q) dependent Nad+ Synthetase 714.0 0 0 0 0 0.9409966898260856 P38795 0.9587849974632264 0.101845420897007 45.38508685051977 40.0 1.0 no 5224 chrVIII_246648 16221 essential YHR074W 455 + CCAGAGACTTGTGCCATTTG Q|153|E Q|153|* QNS1 glutamine (Q) dependent Nad+ Synthetase 714.0 0 0 0 0 0.4073894487224121 P38795 0.9590039849281312 0.04944583401083946 51.27750603401296 50.0 1.0 no 5225 chrVIII_246848r 16225 essential YHR074W 658 - AACACCACCACAACGTTTAG V|226|L V|226|I G|225|A G|225|D QNS1 glutamine (Q) dependent Nad+ Synthetase 714.0 0 0 0 0 0.015616521951050566 P38795 0.9539830088615416 0.9574310183525084 0.9499930143356324 0.9446240067481996 0.2372187376022339 1.0 0.08484616875648499 0.001584555022418499 45.08547668028859 45.0 1.0 no 5226 chrVIII_247067r 16231 essential YHR074W 877 - GAACTTTATTTCTGCCAAGG K|298|N silent|AAG>AAA|K|298 QNS1 glutamine (Q) dependent Nad+ Synthetase 714.0 0 0 0 0 0.7558145207813473 P38795 0.9355990290641784 0.4072419703006744 44.215876178730014 40.0 1.0 no 5227 chrVIII_247130r 16234 essential YHR074W 940 - ACACACTGTAGGATCAAATC silent|GTG>GTC|V|319 silent|GTG>GTA|V|319 C|320|S C|320|Y QNS1 glutamine (Q) dependent Nad+ Synthetase 714.0 0 0 0 1 0.17113567119522952 P38795 0.9421560168266296 0.9290120005607604 0.8323612213134766 0.5589113831520081 40.880489871959576 40.0 1.0 no 5228 chrVIII_247170 16236 essential YHR074W 977 + GCCTTTCTATCACTCTCCTG P|327|R P|327|L P|327|A P|327|S QNS1 glutamine (Q) dependent Nad+ Synthetase 714.0 0 1 0 0 -1.1471376256666304 P38795 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.4361871182918549 0.7066187858581543 0.6461194753646851 0.5257689356803894 55.94755262269132 50.0 1.0 no 5229 chrVIII_247186r 16239 essential YHR074W 996 - CCCAGTGCAATTTCTTCCTC silent|CTG>CTC|L|338 silent|CTG>CTA|L|338 G|339|R G|339|R QNS1 glutamine (Q) dependent Nad+ Synthetase 714.0 0 0 0 0 -0.6771057516141485 P38795 0.941340982913971 0.941340982913971 0.006023090798407793 0.006023090798407793 55.60042990795432 50.0 1.0 no 5230 chrVIII_247311r 16241 essential YHR074W 1121 - TCACTAAACGGCACATAGAG V|380|L V|380|M silent|GTG>GTC|V|380 silent|GTG>GTA|V|380 QNS1 glutamine (Q) dependent Nad+ Synthetase 714.0 0 0 0 0 0.5119226370995312 P38795 0.9539830088615416 0.9587630033493042 0.13546614348888394 0.004412739537656307 -0.03400000184774399 0.06300000101327896 41.936038580046564 45.0 1.0 no 5231 chrVIII_247478r 16246 essential YHR074W 1288 - TGCTCTGTTTCTTGTCTCCT A|436|P A|436|T R|435|T R|435|K QNS1 glutamine (Q) dependent Nad+ Synthetase 714.0 0 0 0 0 -0.4816511775762074 P38795 0.9573720097541808 0.9523990154266356 0.932735025882721 0.955805003643036 0.008545568212866783 0.00747918663546443 0.01610768958926201 0.09034641087055206 56.995432992780934 45.0 1.0 no 5232 chrVIII_247515 16247 essential YHR074W 1322 + TGCAATTGGATCTTACCACG A|442|G A|442|V QNS1 glutamine (Q) dependent Nad+ Synthetase 714.0 0 0 0 0 0.4865282290061808 P38795 0.9484469890594482 0.9504740238189696 0.2998073697090149 0.2434762120246887 46.19972363462097 45.0 1.0 no 5233 chrVIII_247603 16252 essential YHR074W 1410 + CCAATATACAAAATATTTGG P|471|R P|471|L QNS1 glutamine (Q) dependent Nad+ Synthetase 714.0 0 0 0 0 -0.008204237413633603 P38795 0.9432820081710817 0.9430609941482544 0.0015697181224822998 0.002125125611200929 32.828046185948274 25.0 1.0 no 5234 chrVIII_247656 16253 essential YHR074W 1463 + CATCCAGGCGCGTCTAAGAA I|489|M silent|ATC>ATT|I|489 Q|490|E Q|490|* QNS1 glutamine (Q) dependent Nad+ Synthetase 714.0 0 0 0 0 -0.7918908673486622 P38795 0.9598389863967896 0.9590039849281312 0.025558266788721085 0.0 0.0544000007212162 51.39417998913638 55.00000000000001 1.0 no 5235 chrVIII_247726r 16257 essential YHR074W 1536 - ACTAACAATCCACCCGAGTT V|519|L V|519|I L|517|F silent|TTG>TTA|L|517 QNS1 glutamine (Q) dependent Nad+ Synthetase 714.0 0 0 0 0 -0.8071353530860621 P38795 0.9539830088615416 0.9574310183525084 0.9587849974632264 0.0061569344252347955 0.009327976033091543 0.009249244816601276 -0.8575999736785889 48.793297558531656 45.0 1.0 no 5236 chrVIII_272721r 16260 essential YHR083W 97 - CCGCTGTATTTCTAATGCAA Q|38|H silent|CAG>CAA|Q|38 R|39|P R|39|Q SAM35 Sorting and Assembly Machinery 329.0 0 0 0 0 -0.39898884706070026 P14693 0.985951006412506 0.9462770223617554 0.9782379865646362 0.0916658565402031 0.2731509804725647 0.6548577547073364 46.312312857331044 40.0 1.0 no 5237 chrVIII_272753 16264 essential YHR083W 126 + ACATTCACAGAACGCGGTGG T|43|R T|43|I F|44|L silent|TTC>TTT|F|44 SAM35 Sorting and Assembly Machinery 329.0 0 0 0 0 0.4888098399335673 P14693 0.9528260231018066 0.9646379947662354 0.9022229909896852 0.44350314140319824 0.4123811423778534 0.0 48.629425063584854 55.00000000000001 1.0 no 5238 chrVIII_272777 16266 essential YHR083W 150 + AGCTCTGAGTTGACTGTGGA S|51|R silent|AGC>AGT|S|51 S|52|C S|52|F SAM35 Sorting and Assembly Machinery 329.0 0 0 0 0 0.7052812124178454 P14693 0.9573389887809752 0.9720100164413452 0.9521960020065308 0.0846516340970993 0.12175539880990982 0.1726359724998474 51.80918349746407 50.0 1.0 no 5239 chrVIII_272914 16270 essential YHR083W 287 + AGTCTTACCCACGCACTCGC silent|GTC>GTG|V|97 silent|GTC>GTT|V|97 SAM35 Sorting and Assembly Machinery 329.0 0 0 0 0 -0.3338593777432697 P14693 58.088741753509744 60.0 1.0 no 5240 chrVIII_272945r 16271 essential YHR083W 321 - TCATGGTTACAGGTATGCGA E|114|Q E|114|K SAM35 Sorting and Assembly Machinery 329.0 0 0 0 0 -0.6722798108351697 P14693 0.9857460260391236 0.9736970067024232 0.3139162361621857 0.4747701287269592 48.49027871543058 45.0 1.0 no 5241 chrVIII_273294r 16279 essential YHR083W 670 - GAACTTGTTCCGCTTTGTTA K|229|N silent|AAG>AAA|K|229 SAM35 Sorting and Assembly Machinery 329.0 0 0 0 0 -0.11580890426758993 P14693 0.942243993282318 0.6821622848510742 48.500588643482274 40.0 1.0 no 5242 chrVIII_273322r 16280 essential YHR083W 698 - TCTTGACGATTTCTCGATGG K|239|N silent|AAG>AAA|K|239 V|238|L V|238|I SAM35 Sorting and Assembly Machinery 329.0 0 0 0 0 -0.3341847411728278 P14693 0.9648680090904236 0.9786369800567628 0.9863060116767884 0.5208560228347778 0.08883118629455566 0.08726498484611511 45.49056922211071 45.0 1.0 no 5243 chrVIII_273325r 16281 essential YHR083W 701 - TACTCTTGACGATTTCTCGA S|240|T S|240|N K|239|N silent|AAG>AAA|K|239 SAM35 Sorting and Assembly Machinery 329.0 0 0 0 0 0.36961838346652987 P14693 0.9762319922447203 0.98028302192688 0.9648680090904236 0.4536210298538208 0.3863379657268524 0.5208560228347778 44.83552443667093 40.0 1.0 no 5244 chrVIII_277286 16285 essential YHR085W 522 + AAACTTTTGAACGGTGTCTT L|176|V L|176|F IPI1 Involved in Processing ITS2 334.0 0 0 0 0 0.5305592126251113 P38803 0.9703750014305116 0.9798439741134644 0.5105133056640625 0.21455955505371094 41.24046643452056 35.0 1.0 no 5245 chrVIII_280967r 16295 no_effect YHR087W 150 - TCGGCACCCCTACCGTCCTG E|57|Q E|57|K A|56|P A|56|T RTC3 Restriction of Telomere Capping 111.0 0 0 0 0 -0.5625861737641784 P38804 0.956179976463318 0.9475290179252625 0.9573720097541808 0.9523990154266356 0.5014132261276245 0.7347555160522461 0.0743030533194542 0.42286089062690735 0.03680000081658363 -0.3055999875068665 -0.7505999803543091 -0.010599999688565731 -0.9863600134849548 -0.0015999999595806005 64.62734574181229 70.0 1.0 no 5246 chrVIII_281627r 16301 essential YHR088W 135 - AATCTCTGCTCCCGCAGCTC R|51|T R|51|K Q|50|H silent|CAG>CAA|Q|50 RPF1 Ribosome Production Factor 295.0 0 1 0 0 -0.03206698164059614 P38805 0.2061457931995392 0.3384138345718384 0.05001823604106903 60.24617207951701 60.0 1.0 no 5247 chrVIII_281898 16303 essential YHR088W 403 + TATCTGATATTTGTATAAAA S|136|C S|136|F RPF1 Ribosome Production Factor 295.0 0 0 0 0 0.6695356295023116 P38805 0.2437397390604019 0.032401349395513535 29.99841566156164 15.0 1.0 no 5248 chrVIII_281974 16305 essential YHR088W 479 + AACATTCATACATCTGCCAG T|161|R T|161|I F|162|L silent|TTC>TTT|F|162 RPF1 Ribosome Production Factor 295.0 0 0 0 0 0.4210839720866956 P38805 0.02733110822737217 0.8075816631317139 1.0 44.87927741543182 40.0 1.0 no 5249 chrVIII_281975 16306 essential YHR088W 480 + ACATTCATACATCTGCCAGA T|161|R T|161|I F|162|L silent|TTC>TTT|F|162 RPF1 Ribosome Production Factor 295.0 0 0 0 0 -0.1654001682661818 P38805 0.02733110822737217 0.8075816631317139 1.0 47.65052306619867 40.0 1.0 no 5250 chrVIII_282149r 16310 essential YHR088W 657 - CCTTCAATATCAGGATTCTG G|226|R G|226|S E|225|Q E|225|K RPF1 Ribosome Production Factor 295.0 0 0 0 0 -0.8050482729549263 P38805 0.0 0.0 0.7520809173583984 0.8866023421287537 44.37978631583081 40.0 1.0 no 5251 chrVIII_282158r 16311 essential YHR088W 666 - ACTTGTCGACCTTCAATATC V|229|L V|229|I R|227|P R|227|Q RPF1 Ribosome Production Factor 295.0 0 0 0 0 -0.5548412413945665 P38805 0.014252258464694025 0.019835727289319042 0.003009953536093235 0.04136090725660324 45.25991820434529 40.0 1.0 no 5252 chrVIII_282848 16312 essential YHR089C 431 - AAGCACCACCACGGCCACCT A|150|P A|150|T G|149|A G|149|D GAR1 Glycine Arginine Rich 205.0 0 0 0 0 0.8159800551066272 P28007 0.9846779704093932 0.97638601064682 0.9732409715652466 0.9609550237655641 0.13730534911155698 0.17552918195724487 1.0 0.1353866308927536 60.87905756465511 65.0 0.0 no 5253 chrVIII_282849 16313 essential YHR089C 430 - AGCACCACCACGGCCACCTG A|150|P A|150|T G|149|A G|149|D GAR1 Glycine Arginine Rich 205.0 0 0 0 0 -3.343604278127835 P28007 0.9846779704093932 0.97638601064682 0.9732409715652466 0.9609550237655641 0.13730534911155698 0.17552918195724487 1.0 0.1353866308927536 62.55133972909442 70.0 0.0 yes 5254 chrVIII_283009r 16317 essential YHR089C 267 + TTCACTATCAAGTGTGGTGA F|90|L silent|TTC>TTT|F|90 T|91|S T|91|I GAR1 Glycine Arginine Rich 205.0 0 0 0 0 0.05195428141669467 P28007 0.9584370255470276 0.9665899872779846 0.9646379947662354 0.01489891577512026 1.0 0.002397200325503945 1.7054200172424316 0.8292800188064575 2.2207200527191158 1.3147000074386597 2.486920118331909 45.55357502205675 40.0 0.0 no 5255 chrVIII_283153r 16318 essential YHR089C 123 + GCTTTTCTACATCCATGTGA A|42|G A|42|V L|44|V silent|CTA>TTA|L|44 GAR1 Glycine Arginine Rich 205.0 0 0 0 0 0.6458120929279125 P28007 0.9519839882850648 0.9512100219726562 0.9703750014305116 0.2861952781677246 0.3243020176887512 0.6536576151847839 1.2619999647140503 -1.8495800495147705 0.6110000014305115 1.1131999492645264 -0.05316000059247017 0.701479971408844 0.9908999800682068 49.56016256203765 40.0 0.0 no 5256 chrVIII_283154r 16319 essential YHR089C 122 + AGCTTTTCTACATCCATGTG A|42|G A|42|V GAR1 Glycine Arginine Rich 205.0 0 0 0 0 1.0737010660466753 P28007 0.9519839882850648 0.9512100219726562 0.2861952781677246 0.3243020176887512 1.2619999647140503 -1.8495800495147705 1.1131999492645264 -0.05316000059247017 48.386311947354564 40.0 0.0 no 5257 chrVIII_283177 16320 essential YHR089C 102 - CCCATTTCTAGAACAGTGTC M|40|I M|40|I G|41|R G|41|R GAR1 Glycine Arginine Rich 205.0 0 0 0 0 -2.909395337378053 P28007 0.9437090158462524 0.9437090158462524 0.9477360248565674 0.9477360248565674 0.6507714986801147 0.6507714986801147 0.0010555506451055408 0.0010555506451055408 3.9885799884796143 3.9885799884796143 23.40024185180664 23.40024185180664 48.7093078075095 45.0 0.0 yes 5258 chrVIII_315244 16325 essential YHR101C 618 - TCGTGAGCCAGCGTAGTTCC E|213|Q E|213|K 0 0 0 0 -0.16176100594865567 P38813 0.97645902633667 0.9644089937210084 0.2805156111717224 0.3606238067150116 58.910257578907874 60.0 0.0 no 5259 chrVIII_315324r 16326 essential YHR101C 535 + GCCATTATGACAAGTATTTG H|180|D H|180|Y silent|CGC>CGG|R|179 silent|CGC>CGT|R|179 0 0 0 0 -0.355290836394851 P38813 0.9745690226554872 0.9747200012207032 0.875876784324646 0.08559808135032654 41.758920866010605 35.0 0.0 no 5260 chrVIII_315326 16327 essential YHR101C 536 - TCAAATACTTGTCATAATGG L|185|F silent|TTG>TTA|L|185 0 0 0 0 -0.4671048328796312 P38813 0.9229249954223632 0.0 35.88294971635713 30.0 0.0 no 5261 chrVIII_315358 16328 essential YHR101C 504 - TTACGTTCATTAGTGTCCTC R|174|P R|174|H 0 0 0 0 -5.243303205846667 P38813 0.8924970030784607 0.931124985218048 0.0 0.0 48.40383854954365 40.0 0.0 yes 5262 chrVIII_315687 16332 essential YHR101C 175 - TTTCTCAGCCGCTTCAATAA E|64|D silent|GAG>GAA|E|64 E|64|Q E|64|K 0 0 0 0 0.7095701193830019 P38813 0.9686009883880616 0.97645902633667 0.9644089937210084 0.2920561134815216 0.5957615971565247 0.8537044525146484 47.96206862136381 40.0 0.0 no 5263 chrVIII_315744 16333 essential YHR101C 118 - CTCTTGATACTTTAAAATAC E|46|Q E|46|K 0 0 0 0 -0.20919304551612 P38813 0.9857460260391236 0.9736970067024232 0.2682033181190491 0.16064031422138214 32.79631220820147 25.0 0.0 no 5264 chrVIII_316609r 16335 essential YHR102W 40 - ACTCACATCCATCTCTCCTT silent|GTG>GTC|V|19 silent|GTG>GTA|V|19 S|20|T S|20|N KIC1 Kinase that Interacts with Cdc31p 1080.0 0 0 0 0 0.13266841191332554 P38692 0.9512869715690612 0.9536849856376648 1.0 0.4115082919597626 54.67508302615072 45.0 1.0 no 5265 chrVIII_316742 16340 essential YHR102W 170 + TTCTGATTCTGACGAGGTGG S|58|C S|58|F KIC1 Kinase that Interacts with Cdc31p 1080.0 0 0 0 0 -0.5548370791052368 P38692 0.945252001285553 0.9294660091400146 0.12097462266683577 0.010757727548480034 48.103021107329646 50.0 1.0 no 5266 chrVIII_316801 16342 essential YHR102W 229 + AACAGATTTCCAATATCACG Q|78|E Q|78|* KIC1 Kinase that Interacts with Cdc31p 1080.0 0 0 0 0 -0.7107356003684581 P38692 0.9590039849281312 0.0 39.67718872596589 35.0 1.0 no 5267 chrVIII_316810 16343 essential YHR102W 238 + CCAATATCACGCGGTATTAT silent|TCC>TCG|S|80 silent|TCC>TCT|S|80 KIC1 Kinase that Interacts with Cdc31p 1080.0 0 0 0 0 -0.2233217997022025 P38692 45.16834728995661 40.0 1.0 no 5268 chrVIII_316810r 16344 essential YHR102W 241 - CCCATAATACCGCGTGATAT G|87|R G|87|R G|87|A G|87|E KIC1 Kinase that Interacts with Cdc31p 1080.0 0 0 0 0 0.10827254003096272 P38692 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.0 0.0 0.0 0.0 48.58953970701077 45.0 1.0 no 5269 chrVIII_316847 16345 essential YHR102W 275 + CACAAGCCTTTGGATCATAA T|93|R T|93|I S|94|R silent|AGC>AGT|S|94 KIC1 Kinase that Interacts with Cdc31p 1080.0 0 0 0 0 0.10456037370116132 P38692 0.9476869702339172 0.9472420215606691 0.9417110085487366 0.0 0.0 0.2822290956974029 44.492073385447156 40.0 1.0 no 5270 chrVIII_316885 16347 essential YHR102W 313 + GTTCACTGCGTTCGTTGTTA S|106|* S|106|L L|107|V silent|CTG>TTG|L|107 KIC1 Kinase that Interacts with Cdc31p 1080.0 0 0 0 0 -0.1683776701117305 P38692 0.9298099875450134 0.9512209892272948 0.0 0.02652420662343502 51.79532712603868 45.0 1.0 no 5271 chrVIII_316890 16348 essential YHR102W 318 + CTGCGTTCGTTGTTAAGGCC R|108|G R|108|C KIC1 Kinase that Interacts with Cdc31p 1080.0 0 0 0 0 -0.30649637360023313 P38692 0.8994590044021606 0.8926740288734436 0.0 0.0 54.23260722005897 55.00000000000001 1.0 no 5272 chrVIII_317016 16350 essential YHR102W 444 + AACGTTCTGATCACTAACGA N|149|K silent|AAC>AAT|N|149 L|151|V silent|CTG>TTG|L|151 KIC1 Kinase that Interacts with Cdc31p 1080.0 0 1 0 0 -0.3837618385639221 P38692 0.9439849853515624 0.9512209892272948 0.0 0.0 41.76343995170232 40.0 1.0 no 5273 chrVIII_317092 16351 essential YHR102W 520 + TACGACGTCAAACTATGGCT R|175|G R|175|* R|176|G R|176|C KIC1 Kinase that Interacts with Cdc31p 1080.0 0 0 0 0 -0.9618057332693156 P38692 0.8994590044021606 0.8994590044021606 0.8926740288734436 0.012155471369624138 0.0 0.0 -0.4633999764919281 -5.372000217437744 -1.2379000186920166 44.58576101746666 45.0 1.0 no 5274 chrVIII_317215r 16362 essential YHR102W 646 - ATCGCAGTATGGCGGATTTC D|222|H D|222|N C|221|S C|221|Y KIC1 Kinase that Interacts with Cdc31p 1080.0 0 0 0 0 -0.20674437065633366 P38692 0.9486550092697144 0.956179976463318 0.9421560168266296 0.9290120005607604 0.22047078609466556 0.07085579633712769 0.0 0.0 13.006799697875975 2.3929998874664307 -0.358599990606308 0.0908000022172928 50.78518960636825 50.0 1.0 no 5275 chrVIII_317266 16365 essential YHR102W 694 + TCATCAAATCGAAACCACCG I|232|M silent|ATC>ATT|I|232 I|233|M silent|ATC>ATT|I|233 KIC1 Kinase that Interacts with Cdc31p 1080.0 0 0 0 0 -0.6021050806661136 P38692 0.9598389863967896 0.9598389863967896 0.0 0.028004640713334084 -1.8686000108718872 42.6370347449847 45.0 1.0 no 5276 chrVIII_317443 16371 essential YHR102W 871 + TATCACGATATCTACTATTT S|292|* S|292|L R|293|G R|293|* KIC1 Kinase that Interacts with Cdc31p 1080.0 0 0 0 0 0.0001448026382986356 P38692 0.9298099875450134 0.8994590044021606 0.008582951501011848 0.0 37.774821309427644 25.0 1.0 no 5277 chrVIII_317535 16372 essential YHR102W 963 + GCTCCAAAACCATCACAAAA P|323|A P|323|S A|322|G A|322|V KIC1 Kinase that Interacts with Cdc31p 1080.0 0 1 0 0 0.15545498840779387 P38692 0.9562489986419678 0.9498909711837769 0.9484469890594482 0.9504740238189696 0.9041248559951782 0.8871564269065857 0.4020617604255676 0.4024687707424164 41.809476339284345 40.0 1.0 no 5278 chrVIII_317544r 16376 essential YHR102W 975 - TCACCCCCGCCATTTTGTGA G|331|A G|331|D D|332|H D|332|N KIC1 Kinase that Interacts with Cdc31p 1080.0 0 1 0 0 -0.9670188866547074 P38692 0.9499930143356324 0.9446240067481996 0.9486550092697144 0.956179976463318 60.481580784116545 55.00000000000001 1.0 no 5279 chrVIII_317693r 16377 essential YHR102W 1124 - TGTCCTCAGCCAAAGCATCG D|381|H D|381|N E|380|D silent|GAG>GAA|E|380 KIC1 Kinase that Interacts with Cdc31p 1080.0 0 0 0 0 -1.0923450014799212 P38692 0.9486550092697144 0.956179976463318 0.94931298494339 0.013874819502234459 0.14093117415905 0.05597435683012009 53.385440233922225 55.00000000000001 1.0 no 5280 chrVIII_317909 16382 essential YHR102W 1337 + CTCAAAATACCCTTCCAAAA S|447|* S|447|L KIC1 Kinase that Interacts with Cdc31p 1080.0 0 1 0 0 -1.619821393117404 P38692 0.9298099875450134 0.3812318742275238 40.67822386191017 35.0 1.0 no 5281 chrVIII_317934 16383 essential YHR102W 1362 + GCTGGAACTACAAACACCTC A|455|G A|455|V KIC1 Kinase that Interacts with Cdc31p 1080.0 0 0 0 0 -0.6150611289231739 P38692 0.9484469890594482 0.9504740238189696 0.4186999797821045 0.32440316677093506 45.968698497322244 50.0 1.0 no 5282 chrVIII_317945 16384 essential YHR102W 1373 + AAACACCTCTGGAACACATA N|459|K silent|AAC>AAT|N|459 T|460|S T|460|I KIC1 Kinase that Interacts with Cdc31p 1080.0 0 1 0 0 0.5542008463588943 P38692 0.9439849853515624 0.9491789937019348 0.9472420215606691 0.3449346423149109 0.3992578685283661 0.4113922417163849 42.113828065839186 40.0 1.0 no 5283 chrVIII_318096 16387 essential YHR102W 1524 + TCCATTTCATCTCTAAATGC silent|TCC>TCG|S|509 silent|TCC>TCT|S|509 S|509|C S|509|F KIC1 Kinase that Interacts with Cdc31p 1080.0 0 0 1 Series([], Name: modification, dtype: object) 0 0.08249206168189384 P38692 0.034878905862569816 0.02065480314195156 43.823725475418826 35.0 1.0 no 5284 chrVIII_318199 16389 essential YHR102W 1627 + ACCTTCCACCTTTATCCAGT L|544|V L|544|F H|543|Q silent|CAC>CAT|H|543 KIC1 Kinase that Interacts with Cdc31p 1080.0 0 0 0 0 -0.4063858502895157 P38692 0.5017839074134827 0.699734628200531 0.60601806640625 56.567109556177066 45.0 1.0 no 5285 chrVIII_318214r 16391 essential YHR102W 1645 - GCTATAATAATTGTTCCCAC S|555|T S|555|N KIC1 Kinase that Interacts with Cdc31p 1080.0 0 1 0 0 -0.0953141196789114 P38692 0.1675046980381012 0.015893947333097458 43.4884661457549 35.0 1.0 no 5286 chrVIII_318492r 16397 essential YHR102W 1923 - TTACTGACTGTCAACCGCCT S|647|T S|647|N KIC1 Kinase that Interacts with Cdc31p 1080.0 0 0 0 0 0.4812844175270646 P38692 0.785060703754425 0.4875749051570892 52.39378782178426 50.0 1.0 no 5287 chrVIII_318713 16402 essential YHR102W 2141 + AACAAAGTTATCTACTCATA T|715|R T|715|I KIC1 Kinase that Interacts with Cdc31p 1080.0 0 0 0 0 1.6289738595874617 P38692 35.09163259597557 25.0 1.0 no 5288 chrVIII_318741 16403 essential YHR102W 2169 + TCACCCTCAAGGCCACTATT P|725|A P|725|S S|724|* S|724|L KIC1 Kinase that Interacts with Cdc31p 1080.0 0 1 0 0 -2.513608701549113 P38692 0.0 0.0 0.013809998519718649 55.159757781035005 50.0 1.0 yes 5289 chrVIII_318745r 16404 essential YHR102W 2176 - AACTCCAAATAGTGGCCTTG V|732|L V|732|I G|731|A G|731|E KIC1 Kinase that Interacts with Cdc31p 1080.0 0 1 0 0 0.2369690142854849 P38692 0.4584416151046753 0.2831842303276062 0.7823677062988281 0.7480745911598206 46.921573232897465 45.0 1.0 no 5290 chrVIII_318774 16407 essential YHR102W 2202 + TCTCCCAATAGAAAGCCTGC P|736|A P|736|S S|735|C S|735|F KIC1 Kinase that Interacts with Cdc31p 1080.0 0 1 0 0 0.3241693918981277 P38692 0.0 0.0 0.004056444391608238 0.0020936229266226287 50.82488510159124 50.0 1.0 no 5291 chrVIII_318777r 16408 essential YHR102W 2208 - GAACCGGCAGGCTTTCTATT G|742|A G|742|D G|742|R G|742|S KIC1 Kinase that Interacts with Cdc31p 1080.0 0 1 0 0 -1.4015068689105088 P38692 0.9087745547294616 0.6372200846672058 0.5495578050613403 0.8323724269866943 52.530780692608964 50.0 1.0 no 5292 chrVIII_318848 16410 essential YHR102W 2276 + TCCTCCTACGATGAAACCAA P|760|R P|760|L P|760|A P|760|S KIC1 Kinase that Interacts with Cdc31p 1080.0 0 1 0 0 -0.5098131465173034 P38692 0.04230499640107155 0.3792421221733093 0.1488177627325058 0.0746648982167244 46.792013510879364 45.0 1.0 no 5293 chrVIII_327097r 16416 essential YHR107C 917 + ATACAGAAGATTAAGACTTG Y|307|* silent|TAC>TAT|Y|307 CDC12 Cell Division Cycle 407.0 0 0 0 0 -0.9621965230148932 P32468 33.682888204824394 30.0 0.0 no 5294 chrVIII_327219 16419 essential YHR107C 798 - TCGATTTCCACAAGTCCCCA E|273|Q E|273|K CDC12 Cell Division Cycle 407.0 0 0 0 0 -1.6117320639019337 P32468 0.956179976463318 0.9475290179252625 0.015739385038614273 0.012236409820616244 55.26045661668991 50.0 0.0 no 5295 chrVIII_327356 16424 essential YHR107C 661 - ATCTGGATTACTGCCACTTT D|227|H D|227|N CDC12 Cell Division Cycle 407.0 0 1 0 0 0.5539453408785332 P32468 0.9486550092697144 0.956179976463318 49.26009885470666 40.0 0.0 no 5296 chrVIII_327385r 16426 essential YHR107C 629 + TCCATTAGACGCTGATTCTA P|211|R P|211|L P|211|A P|211|S CDC12 Cell Division Cycle 407.0 0 0 0 0 -0.1495944118860598 P32468 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.21938036382198334 0.4042969048023224 1.0 0.8948192596435547 47.19169794159603 40.0 0.0 no 5297 chrVIII_327434 16427 essential YHR107C 583 - TTCTATTACTTGCCTGATTC E|201|Q E|201|K CDC12 Cell Division Cycle 407.0 0 0 0 0 0.4402371363110128 P32468 0.956179976463318 0.9475290179252625 0.5643560290336609 0.8634628057479858 45.77697888991935 35.0 0.0 no 5298 chrVIII_327457 16429 essential YHR107C 560 - ACTTGAACTGTTGTAATTCT K|193|N silent|AAG>AAA|K|193 CDC12 Cell Division Cycle 407.0 0 0 0 0 -0.050169997545277456 P32468 0.9355990290641784 0.0 39.89751636663016 30.0 0.0 no 5299 chrVIII_327500 16431 essential YHR107C 517 - CGCAATAACTGGAATCAGAT A|179|P A|179|T CDC12 Cell Division Cycle 407.0 0 1 0 0 0.7270010120856047 P32468 0.9573720097541808 0.9523990154266356 0.01662287302315235 0.012233103625476359 4.673999786376953 3.400599956512451 40.16284707527024 40.0 0.0 no 5300 chrVIII_327540 16432 essential YHR107C 477 - TTCATAGTCTCAATGTCAAT M|165|I M|165|I CDC12 Cell Division Cycle 407.0 0 0 0 0 -0.9213766756208794 P32468 0.9553959965705872 0.9553959965705872 0.0 0.0 40.47112156308377 30.0 0.0 no 5301 chrVIII_327675 16436 essential YHR107C 342 - TCATCAATAAAATCCACCAA D|121|H D|121|N D|120|H D|120|N CDC12 Cell Division Cycle 407.0 0 0 0 0 0.29778025661502217 P32468 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.004125736653804779 0.009875706396996977 0.0031867905054241423 0.009908623993396759 38.2433960783722 30.0 0.0 no 5302 chrVIII_327618 16438 essential YHR107C 399 - TCAAATTTCTTAGTACGGTA D|140|H D|140|N CDC12 Cell Division Cycle 407.0 0 0 0 0 -1.91920584518738 P32468 0.9486550092697144 0.956179976463318 0.006307004019618034 0.03289151936769485 39.580841673917924 30.0 0.0 no 5303 chrVIII_327701r 16440 essential YHR107C 313 + ACGTGAATAACAACAAAGCC N|105|K silent|AAC>AAT|N|105 CDC12 Cell Division Cycle 407.0 0 0 0 0 0.6441997629820736 P32468 0.9439849853515624 0.14743204414844513 -0.4190000295639038 38.49834528862459 40.0 0.0 no 5304 chrVIII_327718 16441 essential YHR107C 299 - TCACGTTATCTCCAAAACCT V|106|L V|106|M silent|GTG>GTC|V|106 silent|GTG>GTA|V|106 CDC12 Cell Division Cycle 407.0 0 0 0 0 0.10218405261066926 P32468 0.9539830088615416 0.9587630033493042 0.06757713109254837 0.019103744998574257 -0.13519999384880066 -0.1387999951839447 -1.3434998989105225 -1.4779000282287598 45.81437818872257 40.0 0.0 no 5305 chrVIII_327719 16442 essential YHR107C 298 - CACGTTATCTCCAAAACCTG V|106|L V|106|M CDC12 Cell Division Cycle 407.0 0 0 0 0 -0.20660891003119086 P32468 0.9539830088615416 0.9587630033493042 0.06757713109254837 0.019103744998574257 -0.13519999384880066 -0.1387999951839447 -1.3434998989105225 -1.4779000282287598 44.89180599310816 45.0 0.0 no 5306 chrVIII_327908 16446 essential YHR107C 109 - GCTCTCACCACATAACATCA E|42|D silent|GAG>GAA|E|42 S|43|T S|43|N CDC12 Cell Division Cycle 407.0 0 0 0 0 -4.500936569978763 P32468 0.94931298494339 0.9512869715690612 0.9536849856376648 0.03874740749597549 0.17924712598323822 0.01490943878889084 0.6369333267211914 0.17373333871364596 -0.37733331322669983 49.10619739073866 45.0 0.0 yes 5307 chrVIII_327915r 16447 essential YHR107C 99 + ACATTCACCGTGATGTTATG T|34|R T|34|I F|35|L silent|TTC>TTT|F|35 CDC12 Cell Division Cycle 407.0 0 0 0 0 -0.1807997746404616 P32468 0.9476869702339172 0.9472420215606691 0.9387490153312684 0.5609520673751831 0.2978638708591461 0.0 2.121999979019165 44.99385211376318 40.0 0.0 no 5308 chrVIII_327953 16449 essential YHR107C 64 - AACAATTTTATAACGCTGGT V|28|L V|28|I CDC12 Cell Division Cycle 407.0 0 0 0 0 -0.4687694672854252 P32468 0.9539830088615416 0.9574310183525084 0.05958366394042969 0.33373817801475525 38.6440926058408 30.0 0.0 no 5309 chrVIII_344853 16457 essential YHR118C 756 - GCCGTCTTCAATTCTGATTG silent|ACG>ACC|T|258 silent|ACG>ACA|T|258 A|259|P A|259|T ORC6 Origin Recognition Complex 435.0 0 0 0 0 -0.24372408045792104 P38826 0.920873999595642 0.912581980228424 0.29666975140571594 0.9691445231437684 48.81452589832225 45.0 0.0 no 5310 chrVIII_344975 16460 essential YHR118C 634 - CTCATCAGAATCTACATTTC E|218|Q E|218|K D|217|H D|217|N ORC6 Origin Recognition Complex 435.0 0 1 0 0 0.3616890736032282 P38826 0.9202449917793274 0.9081959724426271 0.923143982887268 0.934378981590271 0.5484029650688171 0.7330648303031921 0.04263320192694664 0.13239967823028564 40.72160396957429 35.0 0.0 no 5311 chrVIII_344944 16461 essential YHR118C 665 - CACTTGTAGGGTCACTTTCA S|228|T S|228|N ORC6 Origin Recognition Complex 435.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.01037359330875947 P38826 0.9248650074005128 0.9289150238037108 0.4633971154689789 0.402277022600174 50.23198881130258 45.0 0.0 no 5312 chrVIII_345168 16465 essential YHR118C 441 - TGGCTTTTCCTAACTTTAGT S|153|T S|153|N ORC6 Origin Recognition Complex 435.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.3959732286390592 P38826 0.9745349884033204 0.9785860180854796 0.5116440653800964 0.17695091664791107 47.370245923111895 35.0 0.0 no 5313 chrVIII_345148 16466 essential YHR118C 461 - TTACGAACGAATCATTATTT V|160|L V|160|I ORC6 Origin Recognition Complex 435.0 0 1 0 0 -0.13732674761615635 P38826 0.9131360054016112 0.9208049774169922 0.21784836053848267 0.2336355596780777 35.20735221966828 25.0 0.0 no 5314 chrVIII_345258 16470 essential YHR118C 351 - GGACTGCGTTTGTTCTTTTT S|123|T S|123|N R|122|P R|122|H ORC6 Origin Recognition Complex 435.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.11494916797726405 P38826 0.9916689991950988 0.9957190155982972 0.8819800019264221 0.9198700189590454 0.0 0.0 0.21898308396339414 0.15183882415294647 49.9078954782837 40.0 0.0 no 5315 chrVIII_345589 16472 essential YHR118C 20 - GTACTTCTGCGACACAATGT V|13|L V|13|I E|12|Q E|12|K ORC6 Origin Recognition Complex 435.0 0 0 0 0 -0.09332698259149608 P38826 0.9131360054016112 0.9208049774169922 0.9202449917793274 0.9081959724426271 0.23581282794475555 1.0 0.03389785438776016 0.02720868587493896 47.10469466192478 45.0 0.0 no 5316 chrVIII_353697 16474 essential YHR122W 72 + ACCAAGGACCTTTTGTTAGG silent|ACC>ACG|T|25 silent|ACC>ACT|T|25 T|25|S T|25|I CIA2 Cytosolic Iron-sulfur protein Assembly 231.0 0 0 0 1 0.6506013596232207 P38829 0.9491789937019348 0.9472420215606691 0.7014489769935608 0.16686560213565824 48.51180275876857 45.0 1.0 no 5317 chrVIII_353705r 16476 essential YHR122W 83 - TGCTGAACCCGCCTAACAAA S|34|T S|34|N CIA2 Cytosolic Iron-sulfur protein Assembly 231.0 0 0 0 0 0.4319333269916822 P38829 0.9512869715690612 0.9536849856376648 0.505418598651886 0.4901586472988129 48.91244314569048 50.0 1.0 no 5318 chrVIII_353854r 16484 essential YHR122W 232 - TGCTGGCAAACTATCCTCAT A|84|P A|84|T L|82|F silent|TTG>TTA|L|82 CIA2 Cytosolic Iron-sulfur protein Assembly 231.0 0 0 0 0 -0.4163979129633441 P38829 0.9573720097541808 0.9523990154266356 0.9587849974632264 0.2379027605056763 0.4445966184139252 0.0693027675151825 49.52042181516634 45.0 1.0 no 5319 chrVIII_353978 16489 essential YHR122W 353 + CCCTGAGCACCCGTTAAGTC P|119|R P|119|L P|119|A P|119|S CIA2 Cytosolic Iron-sulfur protein Assembly 231.0 0 0 0 0 -1.99932164225858 P38829 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 57.93451246093093 60.0 1.0 no 5320 chrVIII_354053r 16495 essential YHR122W 431 - CGACTTCAGCCATTTCGTTC V|150|L V|150|I E|149|Q E|149|K CIA2 Cytosolic Iron-sulfur protein Assembly 231.0 0 0 0 0 0.4071407315635757 P38829 0.9539830088615416 0.9574310183525084 0.956179976463318 0.9475290179252625 0.023959612473845482 0.12377779930830002 0.5356068015098572 0.8096839785575867 51.79831119337962 50.0 1.0 no 5321 chrVIII_354092 16497 essential YHR122W 467 + AACAATTACCCATTGTTCTC T|157|R T|157|I CIA2 Cytosolic Iron-sulfur protein Assembly 231.0 0 0 0 0 -1.813136913869072 P38829 0.9476869702339172 0.9472420215606691 0.0 0.0 43.93432786535783 35.0 1.0 no 5322 chrVIII_362277r 16504 essential YHR128W 165 - TCCACAATTTGCTTTTGCAC silent|GTG>GTC|V|61 silent|GTG>GTA|V|61 E|62|Q E|62|K FUR1 5-FluoroURidine resistant 216.0 0 0 0 0 0.15905538498873162 P18562 0.956179976463318 0.9475290179252625 0.5754125714302063 0.820841372013092 47.74116146690835 40.0 1.0 no 5323 chrVIII_362308r 16506 essential YHR128W 196 - GACACCTTCGAAGTTTTCGT V|72|L V|72|I G|71|A G|71|D FUR1 5-FluoroURidine resistant 216.0 0 0 0 0 -0.858547561378967 P18562 0.9539830088615416 0.9574310183525084 0.9499930143356324 0.9446240067481996 0.669694721698761 0.4471152126789093 0.009698937647044659 0.002329398412257433 -0.3583399951457977 -0.5853199958801271 48.45997366790965 45.0 1.0 no 5324 chrVIII_362318 16507 essential YHR128W 203 + CTTCGAAGGTGTCTCATTCA F|69|L silent|TTC>TTT|F|69 FUR1 5-FluoroURidine resistant 216.0 0 0 0 0 0.18045905998128964 P18562 0.9387490153312684 0.008119238540530205 0.04230000078678131 48.53242319082108 45.0 1.0 no 5325 chrVIII_362331 16508 essential YHR128W 216 + TCATTCATGGGTAAAATCTG S|73|* S|73|L F|74|L silent|TTC>TTT|F|74 FUR1 5-FluoroURidine resistant 216.0 0 0 0 0 -0.6084616230593775 P18562 0.9298099875450134 0.9387490153312684 0.2917732298374176 0.1604776680469513 -0.6331400275230408 39.166449948447045 35.0 1.0 no 5326 chrVIII_362513 16514 essential YHR128W 398 + CTTCCTATTAGACCCAATGC F|134|L silent|TTC>TTT|F|134 L|135|V silent|CTA>TTA|L|135 FUR1 5-FluoroURidine resistant 216.0 0 0 0 0 -0.6003918410494611 P18562 0.9387490153312684 0.9512209892272948 1.0 0.1513940691947937 49.75195902810214 45.0 1.0 no 5327 chrVIII_393611r 16520 essential YHR148W 80 - TCATGACCTGAGTGTCCCGG M|33|I M|33|I V|32|L V|32|I IMP3 Interacting with Mpp10p 183.0 0 0 0 0 -3.3974995091008147 P32899 0.9391760230064392 0.9391760230064392 0.9460229873657228 0.9551950097084044 0.6313856840133667 0.6313856840133667 0.06974200159311295 0.6903481483459473 1.8144400119781492 1.8144400119781492 -0.3737600147724152 -0.23122000694274905 57.16638821141851 60.0 1.0 yes 5328 chrVIII_393835 16526 essential YHR148W 301 + TTACTGTTAGTGCCATCTGT T|102|S T|102|I IMP3 Interacting with Mpp10p 183.0 0 0 0 0 2.156157040618392 P32899 0.9288010001182556 0.9256410002708436 0.8332359790802002 0.00816425122320652 50.59545102300472 40.0 1.0 no 5329 chrVIII_393912 16527 essential YHR148W 378 + GCAGTCAAGTTCATTGAACA A|127|G A|127|V silent|GTC>GTG|V|128 silent|GTC>GTT|V|128 IMP3 Interacting with Mpp10p 183.0 0 0 0 0 -0.5419346439310844 P32899 0.929311990737915 0.9301170110702516 0.012835103087127207 0.0039269449189305305 -0.20190000534057614 9.23583984375 44.3844638287049 40.0 1.0 no 5330 chrVIII_425854r 16531 essential YHR164C 3302 + ATCATACACACATTCAGCAG S|1102|* S|1102|L Y|1103|* silent|TAC>TAT|Y|1103 DNA2 DNA synthesis defective 1522.0 0 0 0 0 -6.647290577472358 P38859 0.0 43.866154395335165 40.0 0.0 yes 5331 chrVIII_425931 16532 essential YHR164C 3228 - ACAGTAGTCTTACCAGTCCC V|1083|L V|1083|I DNA2 DNA synthesis defective 1522.0 0 0 0 0 0.04248921627367058 P38859 0.7865960597991943 0.1981062740087509 55.79690346328528 50.0 0.0 no 5332 chrVIII_426066 16535 essential YHR164C 3093 - TCATTTGCATCTCTAAACTT D|1038|H D|1038|N DNA2 DNA synthesis defective 1522.0 0 0 0 0 -0.4559625970450333 P38859 0.1618594229221344 0.4537153244018554 41.496256641449634 30.0 0.0 no 5333 chrVIII_426184r 16539 essential YHR164C 2972 + ACCAGCTGTTTCACCTGGCG P|992|R P|992|L P|992|A P|992|S DNA2 DNA synthesis defective 1522.0 0 0 0 0 -0.8341699094151448 P38859 0.014412760734558104 0.01609333418309689 0.06474383175373077 0.06842797994613647 58.82846820445735 60.0 0.0 no 5334 chrVIII_426271 16540 essential YHR164C 2888 - TTCTATATGTGACCAAATTT R|969|T R|969|K DNA2 DNA synthesis defective 1522.0 0 0 0 0 1.5780640581555594 P38859 0.0 0.0 38.16618105740173 25.0 0.0 no 5335 chrVIII_426319 16541 essential YHR164C 2840 - GCTCTGATTCGACCACACTT E|953|Q E|953|K E|953|D silent|GAG>GAA|E|953 DNA2 DNA synthesis defective 1522.0 0 0 0 0 -0.6781822467060561 P38859 0.5838736891746521 0.9248244762420654 0.6203508973121643 52.166948278352145 50.0 0.0 no 5336 chrVIII_426331r 16542 essential YHR164C 2825 + AGTCACTACCATCCAAAGTG silent|GTC>GTG|V|943 silent|GTC>GTT|V|943 T|944|S T|944|I DNA2 DNA synthesis defective 1522.0 0 0 0 0 -0.219909594211772 P38859 0.7217869162559509 0.19051936268806455 47.07290382153184 45.0 0.0 no 5337 chrVIII_426626 16548 essential YHR164C 2533 - TCCACTTCTGGATTCTCTTG G|851|R G|851|R G|851|A G|851|E DNA2 DNA synthesis defective 1522.0 0 1 0 0 -1.135862312110376 P38859 0.008284065872430801 0.008284065872430801 0.07298999279737473 0.01243243832141161 50.78168000474296 45.0 0.0 no 5338 chrVIII_426778 16550 essential YHR164C 2381 - TTTCAAACTCACCTTCTACC E|800|Q E|800|K DNA2 DNA synthesis defective 1522.0 0 0 0 0 -0.3494747529097784 P38859 0.2992036044597626 0.3867492973804474 46.438727899203464 40.0 0.0 no 5339 chrVIII_426792 16552 essential YHR164C 2367 - TCTACCAGGCCACTTTCTTC E|796|Q E|796|K V|795|L V|795|I DNA2 DNA synthesis defective 1522.0 0 0 0 0 -0.4001457793685363 P38859 0.5906891822814941 0.9388768076896667 0.29806312918663025 0.15372133255004886 55.710048253033285 50.0 0.0 no 5340 chrVIII_426927r 16554 essential YHR164C 2229 + CATCAACTCCAAGAGGTTTT Q|745|E Q|745|* L|746|V L|746|F DNA2 DNA synthesis defective 1522.0 0 0 0 0 0.2290683265344451 P38859 0.690074622631073 0.052326887845993035 0.029298994690179825 45.22483212592238 40.0 0.0 no 5341 chrVIII_426922r 16555 essential YHR164C 2234 + ACTCCAAGAGGTTTTCGGAC silent|CTC>CTG|L|746 silent|CTC>CTT|L|746 L|746|V L|746|F DNA2 DNA synthesis defective 1522.0 0 0 0 0 -0.6442563939705452 P38859 0.052326887845993035 0.029298994690179825 49.42133386000727 50.0 0.0 no 5342 chrVIII_426956 16558 essential YHR164C 2203 - ATTCATACTCATTCTATTTC M|740|I M|740|I DNA2 DNA synthesis defective 1522.0 0 0 0 0 0.3272985176003419 P38859 0.226481094956398 0.226481094956398 39.40008829360824 25.0 0.0 no 5343 chrVIII_427110r 16559 essential YHR164C 2046 + AGCGTTTCATACGAGGTTCA S|683|R silent|AGC>AGT|S|683 DNA2 DNA synthesis defective 1522.0 0 0 0 0 -0.4253319159935517 P38859 0.027284376323223114 49.45985728026722 45.0 0.0 no 5344 chrVIII_427140 16560 essential YHR164C 2019 - TTTCCAGTTTTCACTTCTAA G|679|A G|679|E G|679|R G|679|R DNA2 DNA synthesis defective 1522.0 0 0 0 0 0.7279220004211617 P38859 0.0 0.0 0.0 0.0 44.821183480033945 30.0 0.0 no 5345 chrVIII_427250 16563 essential YHR164C 1909 - TTCTTCAATATCAATCACAT E|643|Q E|643|K E|642|Q E|642|K DNA2 DNA synthesis defective 1522.0 0 0 0 0 -1.4496159909607325 P38859 0.0 0.0 0.0 0.0 37.59160270520289 25.0 0.0 no 5346 chrVIII_427483r 16565 essential YHR164C 1673 + CTCGCATAATAAAATTTCTA S|559|W S|559|L H|560|D H|560|Y DNA2 DNA synthesis defective 1522.0 0 0 0 0 0.5115675407646583 P38859 0.014849704690277575 0.2405587583780289 0.6991484761238098 0.313621461391449 34.7464055422052 25.0 0.0 no 5347 chrVIII_427678r 16573 essential YHR164C 1478 + ACTGGCTAACGACAACCTGT L|494|V silent|CTG>TTG|L|494 A|495|G A|495|V DNA2 DNA synthesis defective 1522.0 0 0 0 0 -0.6108488176864424 P38859 0.20508505403995514 0.4363644421100617 0.3967212736606598 48.705187752524175 50.0 0.0 no 5348 chrVIII_427689 16574 essential YHR164C 1470 - TCGTTAGCCAGTTGAGTTTT D|497|H D|497|N DNA2 DNA synthesis defective 1522.0 0 0 0 0 -0.7029051435395239 P38859 0.0 0.0 50.32071646179611 40.0 0.0 no 5349 chrVIII_427914 16576 essential YHR164C 1245 - AATCGTACTACGCCGTCTCT R|421|P R|421|Q DNA2 DNA synthesis defective 1522.0 0 0 0 0 -2.974793801791152 P38859 0.0 0.0 51.735402264838974 50.0 0.0 yes 5350 chrVIII_428255 16578 essential YHR164C 904 - ATTCTTCCCACAACTTTCCT K|307|N silent|AAG>AAA|K|307 silent|GGG>GGC|G|306 silent|GGG>GGA|G|306 DNA2 DNA synthesis defective 1522.0 0 0 0 0 0.8352157752420201 P38859 0.4624103605747223 52.099189755947286 40.0 0.0 no 5351 chrVIII_428379r 16579 essential YHR164C 777 + TCAACAGGAGATAGCAACGA S|260|* S|260|L T|261|R T|261|I DNA2 DNA synthesis defective 1522.0 0 0 0 0 0.7017011792452749 P38859 0.1698312610387802 0.2916467487812042 0.3504478335380554 42.64651737670891 45.0 0.0 no 5352 chrVIII_428676 16584 essential YHR164C 483 - TTCAGTCGATTAGGGACTAT silent|CTG>CTC|L|167 silent|CTG>CTA|L|167 R|166|P R|166|Q DNA2 DNA synthesis defective 1522.0 0 0 0 0 -0.9314327822336284 P38859 0.05363881960511208 0.15614557266235352 45.29753104551321 40.0 0.0 no 5353 chrVIII_428867r 16589 essential YHR164C 289 + ATTCACAAGTTAAACCGAAA S|98|* S|98|L Q|99|E Q|99|* DNA2 DNA synthesis defective 1522.0 0 0 0 0 0.5860496892521189 P38859 0.7099784016609192 1.0 36.1542433246114 30.0 0.0 no 5354 chrVIII_428871 16590 essential YHR164C 288 - TTCGGTTTAACTTGTGAATT silent|CCG>CCC|P|102 silent|CCG>CCA|P|102 DNA2 DNA synthesis defective 1522.0 0 0 0 0 0.7183538803554105 P38859 40.14198080151317 30.0 0.0 no 5355 chrVIII_428972 16591 essential YHR164C 187 - TGACTTTAGGACACTTGCAT K|68|N silent|AAG>AAA|K|68 DNA2 DNA synthesis defective 1522.0 0 0 0 0 0.3320715017382466 P38859 0.05170102044939995 45.59203158183397 40.0 0.0 no 5356 chrVIII_431500 16595 essential YHR165C 5429 - CACGAAGGACATATAATGCT R|1816|P R|1816|H PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 -1.8092721283753896 P33334 0.0017483575502410529 0.0017530320910736918 40.5197984720686 40.0 0.0 no 5357 chrVIII_431541 16596 essential YHR165C 5388 - CTCATACTATTTTGTATCAA M|1802|I M|1802|I S|1801|T S|1801|N PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 -0.12821656068811732 P33334 0.1990385502576828 0.1990385502576828 0.6525821089744568 0.2613445818424225 37.83252991304914 25.0 0.0 no 5358 chrVIII_431619 16599 essential YHR165C 5310 - ATACCGATCATAACACCTGT G|1776|A G|1776|D G|1776|R G|1776|S PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 -0.03129048413248786 P33334 1.0 0.014824382029473782 0.013937833718955515 0.2641496956348419 45.90273870336415 40.0 0.0 no 5359 chrVIII_431634r 16603 essential YHR165C 5292 + AGCATGTATCCCTCCCCAAC S|1765|R silent|AGC>AGT|S|1765 PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 0.9547814899035736 P33334 0.008873151615262032 58.80197548852489 55.00000000000001 0.0 no 5360 chrVIII_431782 16605 essential YHR165C 5147 - AGTCATTTGTTTCATGTAAT D|1722|H D|1722|N PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 -0.6119876213117779 P33334 0.058295294642448425 0.08784704655408859 40.07441979101793 25.0 0.0 no 5361 chrVIII_431839r 16607 essential YHR165C 5087 + ATCTGCCGCTGACATAACTA S|1697|C S|1697|F A|1698|G A|1698|V PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 -0.2540439802191117 P33334 0.0 0.0 0.025777215138077736 0.007976580411195755 48.60256499536996 45.0 0.0 no 5362 chrVIII_431864 16608 essential YHR165C 5065 - ATTCATCTTGTACGATTTGC M|1694|I M|1694|I K|1693|N silent|AAG>AAA|K|1693 PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 0.26720883820566016 P33334 0.09692898392677307 0.09692898392677307 0.018281048163771633 43.83652299345772 35.0 0.0 no 5363 chrVIII_432084r 16613 essential YHR165C 4842 + AACAGAGCAAATGTCTATGT N|1615|K silent|AAC>AAT|N|1615 PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 -0.2266513259736332 P33334 0.0 40.0296773791821 35.0 0.0 no 5364 chrVIII_432607r 16624 essential YHR165C 4319 + CTTCCGTTACATCACTACTT F|1441|L silent|TTC>TTT|F|1441 R|1442|G R|1442|C PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 0.5769222775960456 P33334 0.466435045003891 0.0442885272204876 0.02961791679263115 47.89552986671402 40.0 0.0 no 5365 chrVIII_432608r 16625 essential YHR165C 4318 + TCTTCCGTTACATCACTACT I|1440|M silent|ATC>ATT|I|1440 F|1441|L silent|TTC>TTT|F|1441 PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 0.3624431582478405 P33334 0.020189302042126656 0.466435045003891 48.690677642979146 40.0 0.0 no 5366 chrVIII_432850 16629 essential YHR165C 4079 - TTCTTGTTTCTCCTTTCACC R|1366|T R|1366|K PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 -1.0489819396382494 P33334 0.0035630196798592815 1.0 52.79005332398259 40.0 0.0 no 5367 chrVIII_432864 16630 essential YHR165C 4065 - TTCACCAGGATATCTAATAA silent|GTG>GTC|V|1361 silent|GTG>GTA|V|1361 V|1361|L V|1361|M PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 -2.0441092823344995 P33334 0.22568951547145846 0.02882474660873413 39.29946899834158 30.0 0.0 yes 5368 chrVIII_432881 16631 essential YHR165C 4048 - TAACGGCTCCGTGGCAACAA silent|CCG>CCC|P|1355 silent|CCG>CCA|P|1355 E|1354|D silent|GAG>GAA|E|1354 PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 -1.2782476075238556 P33334 0.6212602853775024 50.56588078764384 55.00000000000001 0.0 no 5369 chrVIII_432955r 16632 essential YHR165C 3971 + TTCAACCACTTTTACTAAAG S|1325|* S|1325|L T|1326|S T|1326|I PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 -0.8773362299792913 P33334 0.0035474591422826047 0.3247756361961365 0.015881562605500218 37.49984265739579 30.0 0.0 no 5370 chrVIII_433116 16635 essential YHR165C 3813 - ACCTCTTCCATTCTTTGTCT E|1277|D silent|GAG>GAA|E|1277 V|1278|L V|1278|M PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 -0.5125430115362704 P33334 0.3021535277366638 0.7219036221504211 0.2461436688899994 54.115650155357905 40.0 0.0 no 5371 chrVIII_433158r 16636 essential YHR165C 3768 + AACTTACTCTTCTCTATGTG N|1257|K silent|AAC>AAT|N|1257 L|1259|V L|1259|F PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 1.2140084926461552 P33334 0.16355477273464206 0.0985962375998497 0.12241391837596892 42.43786111138973 35.0 0.0 no 5372 chrVIII_433219r 16638 essential YHR165C 3707 + TTCGTTAACGTCAATTAAAT S|1237|W S|1237|L PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 0.8511502061760894 P33334 0.0018682912923395636 0.048929311335086816 35.04591288738152 25.0 0.0 no 5373 chrVIII_433264 16640 essential YHR165C 3665 - CCCAAAACACTGCTCGCCCT W|1228|S W|1228|* W|1228|C W|1228|* PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 -1.2426891963558568 P33334 0.28072819113731384 0.08443153649568558 56.61656679907338 60.0 0.0 no 5374 chrVIII_433280r 16643 essential YHR165C 3646 + TACGTCAGGACGTTAACCTA R|1217|G R|1217|C Q|1218|E Q|1218|* PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 -0.3441063571784706 P33334 0.06983112543821335 0.009458066895604134 0.07078006118535995 46.675443517275816 45.0 0.0 no 5375 chrVIII_433596r 16648 essential YHR165C 3330 + TCTTTCATATTCCAATATTA S|1111|C S|1111|F F|1112|L silent|TTC>TTT|F|1112 PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 0.4685950302687548 P33334 0.028442546725273125 0.010708240792155266 0.0 38.241025863417406 20.0 0.0 no 5376 chrVIII_433831r 16651 essential YHR165C 3095 + AAACAACCTATCTGAAATTT N|1033|K silent|AAC>AAT|N|1033 N|1034|K silent|AAC>AAT|N|1034 PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 0.6621043820899923 P33334 0.01490662433207035 0.14715290069580078 34.661078508038266 25.0 0.0 no 5377 chrVIII_433825 16652 essential YHR165C 3104 - ATACATCCCAAATTTCAGAT V|1041|L V|1041|I D|1040|H D|1040|N PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 0.6701214540934388 P33334 0.7223280668258667 0.4650150239467621 0.01964508183300495 0.29297688603401184 41.606860231431824 30.0 0.0 no 5378 chrVIII_433876r 16655 essential YHR165C 3050 + TTCAGAGATACCACCTCTTC S|1018|* S|1018|L PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 -2.2701697839311348 P33334 0.2477888613939285 49.73798783091132 45.0 0.0 yes 5379 chrVIII_433970 16657 essential YHR165C 2959 - TGCATCGGTAATCTTTTCCA A|993|P A|993|T D|992|H D|992|N PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 -1.101397936884377 P33334 0.008034100756049156 0.06879787892103195 0.0 0.0 48.93056384008514 40.0 0.0 no 5380 chrVIII_434032r 16659 essential YHR165C 2894 + GCCTGTTGATATAACCATGA P|966|R P|966|L P|966|A P|966|S PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 -0.013575005865807122 P33334 0.008944272063672544 0.02992026507854462 0.0734633207321167 0.015010460279881952 46.612415452424784 40.0 0.0 no 5381 chrVIII_434183 16665 essential YHR165C 2746 - GACATCTTTTAGGTCTTCGA V|922|L V|922|I D|921|H D|921|N PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 -2.1794290788985697 P33334 0.3940703570842743 0.3540818989276886 0.0031327735632658005 0.0061417315155267715 46.81365448347634 40.0 0.0 yes 5382 chrVIII_434400r 16668 essential YHR165C 2526 + ACTATGGTTAAAAAAAATCT T|843|S T|843|I PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 0.2444603507420444 P33334 0.1851293593645096 0.0058998330496251574 29.661999548962054 20.0 0.0 no 5383 chrVIII_434743 16674 essential YHR165C 2186 - CTTCAAATTGACGTGTGATA E|735|Q E|735|K PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 -0.7146699649398517 P33334 0.11807894706726076 0.15750399231910706 39.6060040216384 35.0 0.0 no 5384 chrVIII_435110 16679 essential YHR165C 1819 - TGACTTTTTACGTTCTTTTG K|612|N silent|AAG>AAA|K|612 PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 0.481702334119451 P33334 0.002495317254215479 41.15573413454075 30.0 0.0 no 5385 chrVIII_435166 16680 essential YHR165C 1763 - AGTCGAGATGTAAATAAGTT D|594|H D|594|N PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 -1.0288670957527295 P33334 0.0024304629769176245 0.10204055905342102 36.2877545096585 30.0 0.0 no 5386 chrVIII_435477r 16686 essential YHR165C 1449 + TTTCCATTTAATAGAACTAA P|485|A P|485|S P|485|R P|485|L PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 0.559509227314044 P33334 0.041607391089200974 0.05767672136425973 0.007633388973772527 0.11668208241462708 34.2816478162581 20.0 0.0 no 5387 chrVIII_435795 16692 essential YHR165C 1134 - ACCTTATATTCGCTTCTAAT K|384|N silent|AAG>AAA|K|384 V|385|L V|385|I PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 -0.05271016786667737 P33334 0.053208786994218826 0.5481647253036499 1.0 43.43684114829938 30.0 0.0 no 5388 chrVIII_435859 16694 essential YHR165C 1070 - AATCTTCCTCCTCTTCTCTT D|363|H D|363|N E|362|Q E|362|K PRP8 Pre-mRNA Processing 2413.0 0 1 0 0 -1.0830278622374665 P33334 0.007016044110059738 0.04625734686851502 0.3055846989154816 0.3192709684371948 53.623424546082965 40.0 0.0 no 5389 chrVIII_435978 16697 essential YHR165C 951 - TCAGTTACTTCATCTCTAAG D|324|H D|324|N PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 -0.19484803298055506 P33334 0.4574473202228546 0.2671195566654205 42.015263450739276 35.0 0.0 no 5390 chrVIII_436128 16703 essential YHR165C 801 - TCATCATCTTGAGAGTCTAA E|274|Q E|274|K D|273|H D|273|N PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 -0.1174300039438586 P33334 0.5058389902114868 0.5093317031860352 0.1900182068347931 0.14772965013980865 42.51361451951465 35.0 0.0 no 5391 chrVIII_436283 16705 essential YHR165C 646 - TATCCAAGTAGCTGACCATT W|221|C W|221|* W|221|S W|221|* PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 -0.06421533275002338 P33334 0.0 0.0 47.904851735299815 40.0 0.0 no 5392 chrVIII_436383 16707 essential YHR165C 546 - ACTTCTTTGGCTTGCTCCCA V|189|L V|189|I E|188|Q E|188|K PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 -2.0172335913215558 P33334 0.08183390647172928 0.23047469556331635 0.28230351209640503 0.2793864905834198 59.098376423433145 50.0 0.0 yes 5393 chrVIII_436422 16708 essential YHR165C 507 - AACAATTTTAAAATCGCGTG L|175|F silent|TTG>TTA|L|175 PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 0.543430471752691 P33334 0.26236051321029663 34.825312609203195 30.0 0.0 no 5394 chrVIII_436539 16712 essential YHR165C 390 - TCCGGTGGCATCTCGGCTTT silent|CCG>CCC|P|136 silent|CCG>CCA|P|136 E|137|Q E|137|K PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 0.5864364734114305 P33334 0.03466648235917092 0.005518979392945766 60.830193985762996 60.0 0.0 no 5395 chrVIII_436713r 16720 essential YHR165C 213 + CCACCGCCACCACCCCCTCC P|73|A P|73|S P|72|R P|72|L PRP8 Pre-mRNA Processing 2413.0 0 0 0 0 -0.8070683851634549 P33334 71.91656058940208 80.0 0.0 no 5396 chrVIII_437646 16730 essential YHR166C 1385 - ACCATGCTTTGAAGTCTCGA W|468|S W|468|* W|468|C W|468|* CDC23 Cell Division Cycle 626.0 0 0 0 0 -2.6940293694960613 P16522 0.0 0.0 49.24614819830424 45.0 0.0 yes 5397 chrVIII_437659 16731 essential YHR166C 1372 - GTCTCGAGGGCATATATCTA D|464|H D|464|N R|463|P R|463|Q CDC23 Cell Division Cycle 626.0 0 0 0 0 -0.7294644046142521 P16522 0.0 0.0 0.05394351109862328 0.14870916306972504 49.154105812028725 45.0 0.0 no 5398 chrVIII_437683r 16735 essential YHR166C 1345 + CCGCAATAGAATGCTATCGT A|450|G A|450|V silent|GCC>GCG|A|449 silent|GCC>GCT|A|449 CDC23 Cell Division Cycle 626.0 0 0 0 0 0.5169298255223085 P16522 0.0 0.0 46.39620274063453 45.0 0.0 no 5399 chrVIII_437769 16737 essential YHR166C 1262 - TATCCAAAGTTAGTGCTCGA D|427|H D|427|N L|426|F silent|TTG>TTA|L|426 CDC23 Cell Division Cycle 626.0 0 0 0 0 -0.30151483677838864 P16522 0.0242041926831007 1.0 0.0 45.52414965042385 40.0 0.0 no 5400 chrVIII_437952r 16741 essential YHR166C 1076 + TCCGTACCGTCTCAACGATT P|360|R P|360|L P|360|A P|360|S CDC23 Cell Division Cycle 626.0 0 0 0 0 -0.7826487999216853 P16522 0.0 0.0 0.0 0.0 51.4055093314052 50.0 0.0 no 5401 chrVIII_438021r 16743 essential YHR166C 1007 + TACTATTAGTTACAACAATT T|337|S T|337|I CDC23 Cell Division Cycle 626.0 0 0 0 0 1.109080094005659 P16522 0.013381187804043293 0.05537192150950432 33.30508495760972 20.0 0.0 no 5402 chrVIII_438054 16745 essential YHR166C 977 - CCTTTAAAAAAGTGAAATTG K|332|N silent|AAG>AAA|K|332 CDC23 Cell Division Cycle 626.0 0 0 0 0 0.6045822325579777 P16522 0.041570816189050674 30.518724314857078 25.0 0.0 no 5403 chrVIII_438385r 16750 essential YHR166C 643 + CACTGTTGTATTATTTACGA L|216|V silent|CTG>TTG|L|216 CDC23 Cell Division Cycle 626.0 0 0 0 0 1.032812949758828 P16522 0.09629184752702713 40.09776184747233 30.0 0.0 no 5404 chrVIII_438474r 16754 essential YHR166C 554 + GAACATATCATCTATTTTGA N|186|K silent|AAC>AAT|N|186 CDC23 Cell Division Cycle 626.0 0 0 0 0 0.9076325428632775 P16522 0.8131007552146912 36.59215181086154 25.0 0.0 no 5405 chrVIII_438666r 16758 essential YHR166C 362 + ATACAGTAAATTTCTATCGT Y|122|* silent|TAC>TAT|Y|122 CDC23 Cell Division Cycle 626.0 0 0 0 0 -0.3369015736802629 P16522 36.94896815983975 25.0 0.0 no 5406 chrVIII_438851 16762 essential YHR166C 180 - ACACCTTGTTTATTTCTTAG G|66|A G|66|D V|67|L V|67|I CDC23 Cell Division Cycle 626.0 0 0 0 0 0.25926222505144564 P16522 0.8533110618591309 0.6270188093185425 0.30620187520980835 0.18877238035202026 42.85355895734011 30.0 0.0 no 5407 chrVIII_439014 16765 essential YHR166C 17 - TATCATGTATTATTTTATCC D|12|H D|12|N CDC23 Cell Division Cycle 626.0 0 0 0 0 -0.313340235180694 P16522 0.010735722258687021 0.020729834213852882 37.369011458963364 20.0 0.0 no 5408 chrVIII_442249 16767 essential YHR169W 68 + TCAGCCAACCGCTATCCAAA Q|24|E Q|24|* P|25|A P|25|S DBP8 Dead Box Protein 431.0 0 0 0 0 -0.7013744658173393 P38719 0.904374659061432 0.0756022036075592 0.015800215303897858 51.54540490526944 50.0 1.0 no 5409 chrVIII_442281r 16768 essential YHR169W 103 - ATCTCTTCCTTCTAAGATTT D|41|H D|41|N R|40|T R|40|K DBP8 Dead Box Protein 431.0 0 0 0 0 0.7613387316385195 P38719 0.005964238662272693 0.20928484201431274 0.03201930969953537 0.4977815449237824 44.50625427436671 30.0 1.0 no 5410 chrVIII_442355r 16769 essential YHR169W 177 - TCGGACCATTTAGTCAGCAT E|66|Q E|66|K W|64|C W|64|* DBP8 Dead Box Protein 431.0 0 0 0 0 -0.07110939863395174 P38719 0.2642337381839752 0.38586270809173584 0.013817243278026579 -3.170799970626831 50.580862608494556 45.0 1.0 no 5411 chrVIII_442475 16776 essential YHR169W 294 + ATTCGCGTGTCAGTTATAGT R|100|G R|100|C silent|CGC>CGG|R|100 silent|CGC>CGT|R|100 DBP8 Dead Box Protein 431.0 0 0 0 0 0.5884485993409357 P38719 0.007606442552059889 0.000982134835794568 48.45387021003053 40.0 1.0 no 5412 chrVIII_442605r 16784 essential YHR169W 427 - AGCTCTCATTAGCCCTCCAA A|149|P A|149|T R|148|T R|148|K DBP8 Dead Box Protein 431.0 0 0 0 0 -2.21038949656948 P38719 0.05815065279603005 0.35245051980018616 0.06209631264209747 0.6021885275840759 1.4117000102996826 2.3217198848724365 0.6338599920272827 -0.1995999962091446 57.53213879947447 50.0 1.0 yes 5413 chrVIII_442735 16785 essential YHR169W 554 + TCTATTCACTGCAACTATAA L|186|V silent|CTA>TTA|L|186 F|187|L silent|TTC>TTT|F|187 DBP8 Dead Box Protein 431.0 0 0 0 0 0.28017774203488505 P38719 0.0 0.06602735072374344 0.8389800190925598 39.42014675825982 30.0 1.0 no 5414 chrVIII_442909 16790 essential YHR169W 728 + GTACCAATTATTAACATGCG Y|244|* silent|TAC>TAT|Y|244 Q|245|E Q|245|* DBP8 Dead Box Protein 431.0 0 0 0 0 -1.2852137307045135 P38719 0.24818941950798035 40.18310054951513 35.0 1.0 no 5415 chrVIII_442987r 16792 essential YHR169W 809 - ACTGCTTCAGGGTTCTTCTA Q|276|H silent|CAG>CAA|Q|276 K|275|N silent|AAG>AAA|K|275 DBP8 Dead Box Protein 431.0 0 0 0 0 -1.2416780878139022 P38719 0.12296710908412932 0.5353748798370361 53.38174616923283 45.0 1.0 no 5416 chrVIII_442998r 16794 essential YHR169W 820 - CCTCACTTCCAACTGCTTCA silent|GTG>GTC|V|279 silent|GTG>GTA|V|279 R|280|T R|280|K DBP8 Dead Box Protein 431.0 0 0 0 0 0.2252953137706608 P38719 0.3242732286453247 0.7042006254196167 54.571523578797276 50.0 1.0 no 5417 chrVIII_443140r 16798 essential YHR169W 962 - TCACTACAAGCTCAACAGTT V|327|L V|327|M silent|GTG>GTC|V|327 silent|GTG>GTA|V|327 DBP8 Dead Box Protein 431.0 0 0 0 0 -0.9535634513098686 P38719 0.1499997228384018 0.007297586649656295 44.38352977999034 40.0 1.0 no 5418 chrVIII_443141r 16799 essential YHR169W 963 - TTCACTACAAGCTCAACAGT silent|GTG>GTC|V|327 silent|GTG>GTA|V|327 V|327|L V|327|M DBP8 Dead Box Protein 431.0 0 0 0 0 -0.2031569791067352 P38719 0.1499997228384018 0.007297586649656295 44.38352977999034 40.0 1.0 no 5419 chrVIII_443888 16802 essential YHR170W 60 + AACTGTGGTACCCCAATCGA N|21|K silent|AAC>AAT|N|21 NMD3 Nonsense-Mediated mRNA Decay 518.0 0 0 0 0 1.2880803466264257 P38861 0.8970403075218201 51.414995372714536 50.0 1.0 no 5420 chrVIII_444026r 16807 essential YHR170W 201 - GCTCTGATCCATTGTCCAGG R|73|T R|73|K A|74|P A|74|T NMD3 Nonsense-Mediated mRNA Decay 518.0 0 0 0 0 -1.383597161921382 P38861 0.39841389656066895 0.3039807081222534 0.02008391171693802 0.015479711815714838 56.75222238787109 55.00000000000001 1.0 no 5421 chrVIII_444075r 16808 essential YHR170W 250 - CTTCAAACGACGCAAACAAA L|89|F silent|TTG>TTA|L|89 NMD3 Nonsense-Mediated mRNA Decay 518.0 0 0 0 0 -0.6855257425066011 P38861 0.0151884313672781 37.36976059829033 40.0 1.0 no 5422 chrVIII_444100 16809 essential YHR170W 272 + CCTAACAAAAGTCAGATTAG L|92|V silent|CTA>TTA|L|92 T|93|R T|93|I NMD3 Nonsense-Mediated mRNA Decay 518.0 0 0 0 0 -0.06362623990527076 P38861 0.007507483009248972 0.030302692204713818 0.008494877256453037 36.432818920494405 35.0 1.0 no 5423 chrVIII_444100r 16810 essential YHR170W 275 - CCACTAATCTGACTTTTGTT V|98|L V|98|M silent|GTG>GTC|V|98 silent|GTG>GTA|V|98 NMD3 Nonsense-Mediated mRNA Decay 518.0 0 0 0 0 -0.5658548231629811 P38861 0.06246905028820038 0.0860692709684372 44.40131786975502 35.0 1.0 no 5424 chrVIII_444270 16813 essential YHR170W 442 + GATCCTACACTACAAATACT S|149|C S|149|F silent|TCC>TCG|S|149 silent|TCC>TCT|S|149 NMD3 Nonsense-Mediated mRNA Decay 518.0 0 0 0 0 0.8627050226051891 P38861 0.21209293603897092 0.7334279417991638 40.61319549340118 35.0 1.0 no 5425 chrVIII_444273 16814 essential YHR170W 445 + CCTACACTACAAATACTTGG silent|TCC>TCG|S|149 silent|TCC>TCT|S|149 Y|150|* silent|TAC>TAT|Y|150 NMD3 Nonsense-Mediated mRNA Decay 518.0 0 0 0 0 -0.3482520581227432 P38861 41.12776775565419 40.0 1.0 no 5426 chrVIII_444273r 16815 essential YHR170W 448 - CCTCCAAGTATTTGTAGTGT W|155|C W|155|* R|156|T R|156|K NMD3 Nonsense-Mediated mRNA Decay 518.0 0 0 0 0 -2.4764837991399515 P38861 0.0 0.09924992918968199 0.7164437770843506 49.3806228956297 40.0 1.0 yes 5427 chrVIII_444393r 16818 essential YHR170W 568 - CCCGTCCTTAGCTTCACTAA G|196|R G|196|R G|196|A G|196|E NMD3 Nonsense-Mediated mRNA Decay 518.0 0 0 0 0 0.6550713007647845 P38861 0.0 0.0 0.0 0.0 54.93058638628395 50.0 1.0 no 5428 chrVIII_444442r 16819 essential YHR170W 617 - AATCAATCATCTTAACTGCG D|212|H D|212|N NMD3 Nonsense-Mediated mRNA Decay 518.0 0 0 0 0 0.01684807385051812 P38861 0.04147837683558464 0.017102610319852832 39.255269097548926 35.0 1.0 no 5429 chrVIII_444482r 16820 essential YHR170W 657 - TCAGACTTTTTATGTTTAAT E|226|Q E|226|K K|224|N silent|AAG>AAA|K|224 NMD3 Nonsense-Mediated mRNA Decay 518.0 0 0 0 0 1.1561489898936688 P38861 0.6564479470252991 0.4615383744239807 0.5444577336311339 36.21569522980411 20.0 1.0 no 5430 chrVIII_444574 16821 essential YHR170W 746 + TCCTATCTGTAAAGATGACT P|250|R P|250|L P|250|A P|250|S NMD3 Nonsense-Mediated mRNA Decay 518.0 0 0 0 0 0.3467641374316667 P38861 0.0 0.0 0.0 0.0 41.77835049102959 35.0 1.0 no 5431 chrVIII_444575r 16822 essential YHR170W 750 - ACCAAGTCATCTTTACAGAT L|256|F silent|TTG>TTA|L|256 V|257|L V|257|I NMD3 Nonsense-Mediated mRNA Decay 518.0 0 0 0 0 0.07268031560078189 P38861 0.009816455654799938 0.05407516285777092 0.019980709999799732 43.9692125730852 35.0 1.0 no 5432 chrVIII_444664 16824 essential YHR170W 836 + TTCTAACACTGTCCAGTTTA S|280|C S|280|F N|281|K silent|AAC>AAT|N|281 NMD3 Nonsense-Mediated mRNA Decay 518.0 0 0 0 0 -0.7026916190940806 P38861 0.02034209854900837 0.009925513528287409 0.04695498570799828 45.496589232045146 35.0 1.0 no 5433 chrVIII_444715 16826 essential YHR170W 887 + GTCACCATCTGTGTACTGGA S|297|* S|297|L P|298|A P|298|S NMD3 Nonsense-Mediated mRNA Decay 518.0 0 0 0 0 0.12637667236065814 P38861 0.3357972204685211 1.0 0.6720166802406311 53.37740642419817 50.0 1.0 no 5434 chrVIII_444751r 16831 essential YHR170W 926 - CCAACTGGGTCACATCAGCC L|315|F silent|TTG>TTA|L|315 Q|314|H silent|CAG>CAA|Q|314 NMD3 Nonsense-Mediated mRNA Decay 518.0 0 0 0 0 0.9820332324432264 P38861 0.01105836033821106 0.20527926087379456 56.22444161060315 60.0 1.0 no 5435 chrVIII_444766r 16834 essential YHR170W 941 - GAACAATGAACTCCACCAAC V|320|L V|320|I NMD3 Nonsense-Mediated mRNA Decay 518.0 0 0 0 0 0.3902813157448707 P38861 0.01797664351761341 0.3873453736305237 42.087524281815426 45.0 1.0 no 5436 chrVIII_444962 16838 essential YHR170W 1134 + TACAACTCAGATCTTTTTGA Y|379|* silent|TAC>TAT|Y|379 N|380|K silent|AAC>AAT|N|380 NMD3 Nonsense-Mediated mRNA Decay 518.0 0 0 0 0 -0.4673244443235497 P38861 0.010512852109968662 39.686126508359344 30.0 1.0 no 5437 chrVIII_448380 16839 essential YHR172W 45 + ACCAACAATATTCCGTTACT silent|ACC>ACG|T|16 silent|ACC>ACT|T|16 T|16|S T|16|I 0 0 0 1 0.5269247946574412 P38863 0.9491789937019348 0.9472420215606691 0.9106877446174622 0.23613102734088895 43.86322375534621 35.0 1.0 no 5438 chrVIII_448632r 16843 essential YHR172W 300 - CTACTGAATGTTTTGAATGA S|106|T S|106|N 0 0 0 0 0.2245849274192873 P38863 0.9512869715690612 0.9536849856376648 0.1694314330816269 0.05341184139251709 36.85677476885184 30.0 1.0 no 5439 chrVIII_449006 16846 essential YHR172W 671 + CAGCTTGCACTTACGATTAA S|225|R silent|AGC>AGT|S|225 0 0 0 0 -0.2394497626662663 P38863 0.9417110085487366 0.211628332734108 44.343435954127706 40.0 1.0 no 5440 chrVIII_449058r 16848 essential YHR172W 726 - TTCAATATGGCACCACCTTT L|248|F silent|TTG>TTA|L|248 0 0 0 0 -3.0669082020714997 P38863 0.9587849974632264 0.02450605295598507 49.105042873755856 40.0 1.0 yes 5441 chrVIII_449059r 16849 essential YHR172W 727 - TTTCAATATGGCACCACCTT L|248|F silent|TTG>TTA|L|248 0 0 0 0 0.8356959630330951 P38863 0.9587849974632264 0.02450605295598507 49.105042873755856 40.0 1.0 no 5442 chrVIII_449098 16851 essential YHR172W 763 + TACTGGAAAATTTGGGTGAT L|256|V silent|CTG>TTG|L|256 0 0 0 0 0.380284718944758 P38863 0.9512209892272948 0.2811470329761505 39.28898902524901 35.0 1.0 no 5443 chrVIII_449222r 16855 essential YHR172W 890 - CATCATAAGTCATGAATTCT D|303|H D|303|N 0 0 0 0 -0.7478014516739581 P38863 0.9486550092697144 0.956179976463318 0.017506521195173264 0.3253290355205536 38.31928183383071 30.0 1.0 no 5444 chrVIII_449383r 16859 essential YHR172W 1051 - AACAACTTTGAGTAAAATAC V|357|L V|357|I V|356|L V|356|I 0 0 0 0 0.6719161037150427 P38863 0.9539830088615416 0.9574310183525084 0.9539830088615416 0.9574310183525084 0.3759327232837677 0.8858354091644287 0.8734597563743591 0.9902550578117372 30.56049521915975 25.0 1.0 no 5445 chrVIII_449746r 16864 essential YHR172W 1414 - CATCAGGTTGTTTGGATTTT silent|CTG>CTC|L|477 silent|CTG>CTA|L|477 0 0 0 0 0.6613746294886936 P38863 45.55357502205681 35.0 1.0 no 5446 chrVIII_449850r 16865 essential YHR172W 1518 - TCATTTGCTGAGTTATTCTC D|513|H D|513|N 0 0 0 0 0.2375613502113516 P38863 0.9486550092697144 0.956179976463318 0.13700129091739655 0.6058980226516724 45.09780271883437 35.0 1.0 no 5447 chrVIII_450110 16870 essential YHR172W 1775 + ACAATACCACTCAAGGCTTT Q|593|E Q|593|* Y|594|* silent|TAC>TAT|Y|594 0 0 0 0 0.3196367889015813 P38863 0.9590039849281312 0.5030932426452637 45.95170921102073 40.0 1.0 no 5448 chrVIII_450148 16871 essential YHR172W 1813 + ACTTAAACAAAACACCCAGC D|605|E silent|GAC>GAT|D|605 0 0 0 0 1.1397896132094196 P38863 0.9532920122146606 1.0 40.82487983772757 40.0 1.0 no 5449 chrVIII_477158 16876 essential YHR186C 3495 - GCATTATACTCAACACTGCC A|1172|P A|1172|T KOG1 Kontroller Of Growth 1557.0 0 0 0 0 -0.15429781030251946 P38873 0.9573720097541808 0.9523990154266356 0.2414694577455521 0.5031774044036865 47.84671073650344 45.0 0.0 no 5450 chrVIII_477428r 16884 essential YHR186C 3222 + GCTAAACTTTTCCAGAGTCT A|1075|G A|1075|V L|1077|V L|1077|F KOG1 Kontroller Of Growth 1557.0 0 0 0 0 -0.3236313475820585 P38873 0.9484469890594482 0.9504740238189696 0.9512209892272948 0.9587849974632264 0.4781540930271149 0.2670734822750092 0.3019317388534546 0.1254289448261261 47.017083745652094 40.0 0.0 no 5451 chrVIII_477526r 16887 essential YHR186C 3124 + GATCATTCTCACCAAATGAG S|1043|* S|1043|L KOG1 Kontroller Of Growth 1557.0 0 1 0 0 -0.5697394208607572 P38873 0.9298099875450134 0.3273196816444397 41.97081560629414 40.0 0.0 no 5452 chrVIII_477599r 16889 essential YHR186C 3051 + AGCTCGAAAGCTCACCAAAC S|1018|R silent|AGC>AGT|S|1018 S|1019|W S|1019|L KOG1 Kontroller Of Growth 1557.0 0 0 0 0 -0.7393349255839129 P38873 0.9417110085487366 0.9288619756698608 0.9298099875450134 0.2948474884033203 0.016729015856981274 0.17179696261882782 45.85469587814725 50.0 0.0 no 5453 chrVIII_477766 16893 essential YHR186C 2887 - TTTCCAAACAGTGTAGAAAA W|968|C W|968|* W|968|S W|968|* KOG1 Kontroller Of Growth 1557.0 0 0 0 0 -0.6236024696061906 P38873 0.8858469724655151 0.8858469724655151 0.010828861035406591 0.026462296023964882 36.46696266515136 30.0 0.0 no 5454 chrVIII_478340 16897 essential YHR186C 2313 - ATACATACAAACCTGTTTAA C|777|S C|777|Y KOG1 Kontroller Of Growth 1557.0 0 0 0 0 1.1088705531798793 P38873 0.9421560168266296 0.9290120005607604 0.7644324898719788 1.0 36.284082002029656 25.0 0.0 no 5455 chrVIII_478351r 16899 essential YHR186C 2299 + TTGCTGATAACCCCTTAAAC A|768|G A|768|V KOG1 Kontroller Of Growth 1557.0 0 0 0 0 -1.1775185696177046 P38873 0.9484469890594482 0.9504740238189696 0.3803938031196594 0.2881455421447754 44.94835634287614 40.0 0.0 no 5456 chrVIII_478392 16900 essential YHR186C 2261 - TAACACACCACTGTCTTAGT V|760|L V|760|I C|759|S C|759|Y KOG1 Kontroller Of Growth 1557.0 0 0 0 0 -1.7430630438878538 P38873 0.9539830088615416 0.9574310183525084 0.9421560168266296 0.9290120005607604 0.43154892325401306 0.5489783883094788 0.5003835558891296 0.17342069745063782 46.18315305959987 40.0 0.0 no 5457 chrVIII_478393 16901 essential YHR186C 2260 - AACACACCACTGTCTTAGTA V|760|L V|760|I C|759|S C|759|Y KOG1 Kontroller Of Growth 1557.0 0 0 0 0 0.2267283279782499 P38873 0.9539830088615416 0.9574310183525084 0.9421560168266296 0.9290120005607604 0.43154892325401306 0.5489783883094788 0.5003835558891296 0.17342069745063782 46.18315305959987 40.0 0.0 no 5458 chrVIII_478483r 16902 essential YHR186C 2167 + TCGTTCGAAACTTTCCTCTG F|723|L silent|TTC>TTT|F|723 R|725|G R|725|* KOG1 Kontroller Of Growth 1557.0 0 0 0 0 -0.222050691588943 P38873 0.9387490153312684 0.8994590044021606 0.8185949325561523 0.2525395750999451 46.73462902751624 45.0 0.0 no 5459 chrVIII_478484r 16903 essential YHR186C 2166 + TTCGTTCGAAACTTTCCTCT F|723|L silent|TTC>TTT|F|723 R|725|G R|725|* KOG1 Kontroller Of Growth 1557.0 0 0 0 0 -0.5274458951817186 P38873 0.9387490153312684 0.8994590044021606 0.8185949325561523 0.2525395750999451 47.006024972027724 40.0 0.0 no 5460 chrVIII_478485r 16904 essential YHR186C 2165 + ATTCGTTCGAAACTTTCCTC F|723|L silent|TTC>TTT|F|723 KOG1 Kontroller Of Growth 1557.0 0 0 0 0 -0.4808157818872849 P38873 0.9387490153312684 0.8185949325561523 45.25233217827451 40.0 0.0 no 5461 chrVIII_478679r 16907 essential YHR186C 1971 + GGCTCAGCCATGATAAATAG silent|GGC>GGG|G|658 silent|GGC>GGT|G|658 S|659|* S|659|L KOG1 Kontroller Of Growth 1557.0 0 0 0 0 -0.03302632810309227 P38873 0.9298099875450134 0.23951153457164764 45.3416197403252 45.0 0.0 no 5462 chrVIII_478715 16908 essential YHR186C 1938 - ATGCCATTAACACCCCAATC G|652|A G|652|D G|652|R G|652|S KOG1 Kontroller Of Growth 1557.0 0 0 0 0 -2.9737205572044982 P38873 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.8607666492462158 0.6368288993835449 0.5990055799484253 0.8048273921012878 50.12088846054906 45.0 0.0 yes 5463 chrVIII_478818 16913 essential YHR186C 1835 - TACGGGCCCAAATAAAAACT R|618|P R|618|H A|617|P A|617|T KOG1 Kontroller Of Growth 1557.0 0 0 0 0 -1.8718515113272296 P38873 0.9099509716033936 0.9570810198783876 0.9573720097541808 0.9523990154266356 0.0 0.0 0.024566194042563442 0.3344208300113678 41.124117333472206 40.0 0.0 no 5464 chrVIII_479238 16919 essential YHR186C 1415 - TACTTCCGGCTTTCGTATCT S|478|T S|478|N G|477|A G|477|E KOG1 Kontroller Of Growth 1557.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.5312207979541141 P38873 0.9512869715690612 0.9536849856376648 0.9499930143356324 0.9438679814338684 0.3850143253803253 0.2924621403217316 0.7362184524536133 1.0 52.63886429234231 45.0 0.0 no 5465 chrVIII_479239 16920 essential YHR186C 1414 - ACTTCCGGCTTTCGTATCTT S|478|T S|478|N G|477|A G|477|E KOG1 Kontroller Of Growth 1557.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.3854273762438908 P38873 0.9512869715690612 0.9536849856376648 0.9499930143356324 0.9438679814338684 0.3850143253803253 0.2924621403217316 0.7362184524536133 1.0 53.47421266603379 45.0 0.0 no 5466 chrVIII_479453 16925 essential YHR186C 1200 - ACAGGATGGCAATTGTACCA V|407|L V|407|I KOG1 Kontroller Of Growth 1557.0 0 0 0 0 -3.601904343937294 P38873 0.9539830088615416 0.9574310183525084 0.6026143431663513 0.9182205200195312 48.220875549037935 45.0 0.0 yes 5467 chrVIII_479470r 16926 essential YHR186C 1180 + TAGCCAAAAGAATAATGCCG A|395|G A|395|V silent|GCC>GCG|A|395 silent|GCC>GCT|A|395 KOG1 Kontroller Of Growth 1557.0 0 0 0 0 -0.6520380486238644 P38873 0.9484469890594482 0.9504740238189696 0.02934212610125542 0.14897668361663818 40.15084792957315 40.0 0.0 no 5468 chrVIII_479645 16930 essential YHR186C 1008 - ATTCCAGGGATATTGACGTT G|342|A G|342|E G|342|R G|342|R KOG1 Kontroller Of Growth 1557.0 0 0 0 0 -0.7667402447720775 P38873 0.9499930143356324 0.9438679814338684 0.941340982913971 0.941340982913971 0.0 0.0 0.0 0.0 47.02594461946751 40.0 0.0 no 5469 chrVIII_479648r 16931 essential YHR186C 1002 + ATACCCAACGTCAATATCCC P|336|A P|336|S P|336|R P|336|L KOG1 Kontroller Of Growth 1557.0 0 0 0 0 0.6840833608260708 P38873 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 1.0 0.7739544510841371 0.2965134382247925 0.2428695857524872 49.165772975497475 45.0 0.0 no 5470 chrVIII_479819 16934 essential YHR186C 834 - AACAAATCTGCGGGTAGTTC L|284|F silent|TTG>TTA|L|284 KOG1 Kontroller Of Growth 1557.0 0 0 0 0 -2.2434332250797286 P38873 0.9587849974632264 0.0206917654722929 44.688518954779795 45.0 0.0 yes 5471 chrVIII_480331 16944 essential YHR186C 322 - GTCTACCCATGCTTCAACTC D|114|H D|114|N V|113|L V|113|I KOG1 Kontroller Of Growth 1557.0 0 0 0 0 -1.1406355103244796 P38873 0.9486550092697144 0.956179976463318 0.9539830088615416 0.9574310183525084 0.0 0.0 0.5201144218444824 0.5238211750984192 53.40219681445154 50.0 0.0 no 5472 chrVIII_480337 16946 essential YHR186C 316 - CCATGCTTCAACTCTGGCAC W|112|S W|112|* A|111|P A|111|T KOG1 Kontroller Of Growth 1557.0 0 0 0 0 -1.3283294834040331 P38873 0.8858469724655151 0.9573720097541808 0.9523990154266356 0.0029773556161671877 0.0619453676044941 0.06431514024734497 53.71736131421074 55.00000000000001 0.0 no 5473 chrVIII_480488 16948 essential YHR186C 165 - TCTCGTTGTTTATCCTCTTC R|61|P R|61|Q D|62|H D|62|N KOG1 Kontroller Of Growth 1557.0 0 0 0 0 1.0200097113339803 P38873 0.9099509716033936 0.949662983417511 0.9486550092697144 0.956179976463318 50.75696698660596 40.0 0.0 no 5474 chrVIII_480450 16950 essential YHR186C 203 - TCTTCCAATCGGTAATCGGC K|74|N silent|AAG>AAA|K|74 W|73|C W|73|* KOG1 Kontroller Of Growth 1557.0 0 0 0 0 -0.2958736342022668 P38873 0.9355990290641784 0.8858469724655151 0.0165997501462698 0.0 49.952885414043855 50.0 0.0 no 5475 chrVIII_482788 16963 essential YHR188C 1030 - AACTGACAAAAACGCAGTCC V|350|L V|350|I L|348|F silent|TTG>TTA|L|348 GPI16 GlycosylPhosphatidylInositol anchor biosynthesis 610.0 0 0 0 0 -0.22308395326023667 P38875 0.9539830088615416 0.9574310183525084 0.9587849974632264 0.3181815445423126 0.1933220773935318 0.4811628460884094 41.345476792675406 45.0 0.0 no 5476 chrVIII_482822 16964 essential YHR188C 996 - ACTTCTGCACAAATTCTTGT V|339|L V|339|I E|338|Q E|338|K GPI16 GlycosylPhosphatidylInositol anchor biosynthesis 610.0 0 0 0 0 0.8718506878790526 P38875 0.9539830088615416 0.9574310183525084 0.956179976463318 0.9475290179252625 0.5377108454704285 0.432875007390976 0.5476366877555847 0.8781711459159851 44.06098457336713 35.0 0.0 no 5477 chrVIII_482922r 16969 essential YHR188C 893 + TTACCAATGCTTCCCTCTAC Y|299|* silent|TAC>TAT|Y|299 Q|300|E Q|300|* GPI16 GlycosylPhosphatidylInositol anchor biosynthesis 610.0 0 0 0 0 -2.0997442246871527 P38875 0.9590039849281312 0.5979663133621216 51.774896537954255 45.0 0.0 yes 5478 chrVIII_482972 16972 essential YHR188C 846 - CGCAATGTGTTCCCATCCAA L|288|F silent|TTG>TTA|L|288 GPI16 GlycosylPhosphatidylInositol anchor biosynthesis 610.0 0 0 0 0 -1.0805837153762097 P38875 0.9587849974632264 0.11019958555698396 53.06013351550024 50.0 0.0 no 5479 chrVIII_482984r 16974 essential YHR188C 831 + CCTATCCCCAAACCTTTGGA P|278|R P|278|L I|279|M silent|ATC>ATT|I|279 GPI16 GlycosylPhosphatidylInositol anchor biosynthesis 610.0 0 0 0 0 -0.2867782140294921 P38875 0.9432820081710817 0.9430609941482544 0.9598389863967896 0.0327291376888752 0.04104937613010407 0.010578845627605915 54.24190728393739 50.0 0.0 no 5480 chrVIII_483007 16975 essential YHR188C 811 - TCTCTCACCTCTTGCCAAGG E|276|D silent|GAG>GAA|E|276 R|277|T R|277|K GPI16 GlycosylPhosphatidylInositol anchor biosynthesis 610.0 0 0 0 0 0.20469122667344344 P38875 0.94931298494339 0.932735025882721 0.955805003643036 0.5417642593383789 0.3277008533477783 0.4853932857513428 56.34649398365138 55.00000000000001 0.0 no 5481 chrVIII_483021r 16976 essential YHR188C 794 + AACACACGTTCCCTCCGCCT T|266|R T|266|I H|267|D H|267|Y GPI16 GlycosylPhosphatidylInositol anchor biosynthesis 610.0 0 0 0 0 0.027137655345625008 P38875 0.9476869702339172 0.9472420215606691 0.9473130106925964 0.9489949941635132 0.012627354823052885 0.6059590578079224 1.0 0.03893432393670082 59.82729407399511 60.0 0.0 no 5482 chrVIII_483063r 16979 essential YHR188C 752 + TGCTCTTTGTCACTACGAGA A|252|G A|252|V L|253|V L|253|F GPI16 GlycosylPhosphatidylInositol anchor biosynthesis 610.0 0 0 0 0 0.4984832258180016 P38875 0.9484469890594482 0.9504740238189696 0.9512209892272948 0.9587849974632264 0.379807323217392 0.2862709164619446 0.29074859619140625 0.05530497059226036 48.84979116904111 45.0 0.0 no 5483 chrVIII_483088 16980 essential YHR188C 730 - TTCATCTTCAGAACAAATAG E|250|Q E|250|K D|249|H D|249|N GPI16 GlycosylPhosphatidylInositol anchor biosynthesis 610.0 0 0 0 0 0.18006119278035926 P38875 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.13463521003723145 0.13960705697536469 0.10322547703981401 0.3921487927436829 35.28188711717928 30.0 0.0 no 5484 chrVIII_483306 16987 essential YHR188C 512 - TATCAGAAGCATATGACCGC D|177|H D|177|N GPI16 GlycosylPhosphatidylInositol anchor biosynthesis 610.0 0 0 0 0 0.060109269817656415 P38875 0.9486550092697144 0.956179976463318 0.0855424553155899 0.9035654067993164 45.516127012136224 45.0 0.0 no 5485 chrVIII_483308 16990 essential YHR188C 510 - TCAGAAGCATATGACCGCCG D|177|H D|177|N GPI16 GlycosylPhosphatidylInositol anchor biosynthesis 610.0 0 0 0 0 -0.2782726023637637 P38875 0.9486550092697144 0.956179976463318 0.0855424553155899 0.9035654067993164 50.54366707511241 55.00000000000001 0.0 no 5486 chrVIII_483325r 16992 essential YHR188C 490 + AGTCAAGGACGACCTTTCCC S|165|* S|165|L GPI16 GlycosylPhosphatidylInositol anchor biosynthesis 610.0 0 0 0 0 -3.3731707254333902 P38875 0.9298099875450134 0.16267231106758118 54.106022918304575 55.00000000000001 0.0 yes 5487 chrVIII_483380r 16993 essential YHR188C 435 + AAACTGTCCAATTCATTGAG L|147|V silent|CTG>TTG|L|147 GPI16 GlycosylPhosphatidylInositol anchor biosynthesis 610.0 0 0 0 0 -1.55955319569567 P38875 0.9512209892272948 0.11309549957513808 39.85460520485486 35.0 0.0 no 5488 chrVIII_483415 16994 essential YHR188C 403 - GAACGCCTGTTCCTGATCCA silent|GCG>GCC|A|140 silent|GCG>GCA|A|140 A|140|P A|140|T GPI16 GlycosylPhosphatidylInositol anchor biosynthesis 610.0 0 0 0 0 -0.1680589832010423 P38875 0.9573720097541808 0.9523990154266356 0.016408829018473625 0.015652766451239586 56.024663044488996 55.00000000000001 0.0 no 5489 chrVIII_483448 16997 essential YHR188C 370 - CGACCACAATTCCACACCTG W|129|C W|129|* W|129|S W|129|* GPI16 GlycosylPhosphatidylInositol anchor biosynthesis 610.0 0 0 0 0 -0.4814973957921538 P38875 0.8858469724655151 0.8858469724655151 0.00753991911187768 0.015569002367556097 50.97322988183817 55.00000000000001 0.0 no 5490 chrVIII_483570r 17004 essential YHR188C 245 + ACGGGCCATCCCACCATTGT R|83|G R|83|W A|84|G A|84|V GPI16 GlycosylPhosphatidylInositol anchor biosynthesis 610.0 0 0 0 0 -0.15821870940687935 P38875 0.8994590044021606 0.9448130130767822 0.9484469890594482 0.9504740238189696 0.016847772523760796 0.0036401890683919187 0.17219097912311554 0.9460923075675964 61.51576528788769 60.0 0.0 no 5491 chrVIII_483589r 17009 essential YHR188C 226 + AGCACTACACGACTTTCCCA H|77|D H|77|Y H|77|Q silent|CAC>CAT|H|77 GPI16 GlycosylPhosphatidylInositol anchor biosynthesis 610.0 0 0 0 0 0.1525774213621084 P38875 0.9473130106925964 0.9489949941635132 0.9588389992713928 0.06292062997817993 0.010426258668303491 0.13691480457782745 53.020111062229894 50.0 0.0 no 5492 chrVIII_483610 17010 essential YHR188C 208 - CTCATACGCATCATATGACA E|76|Q E|76|K silent|GCG>GCC|A|74 silent|GCG>GCA|A|74 GPI16 GlycosylPhosphatidylInositol anchor biosynthesis 610.0 0 0 0 0 -0.3411500274562597 P38875 0.956179976463318 0.9475290179252625 0.5517476797103882 1.0 44.13465979811775 40.0 0.0 no 5493 chrVIII_483619 17011 essential YHR188C 199 - ATCATATGACATGGATGATA D|73|H D|73|N GPI16 GlycosylPhosphatidylInositol anchor biosynthesis 610.0 0 0 0 0 -1.258346219951796 P38875 0.9486550092697144 0.956179976463318 0.09953437745571136 0.3733442723751068 38.213905309552615 30.0 0.0 no 5494 chrVIII_483713 17014 essential YHR188C 105 - AACACCAGTGCTTCGTCGTA silent|GTG>GTC|V|41 silent|GTG>GTA|V|41 V|41|L V|41|M GPI16 GlycosylPhosphatidylInositol anchor biosynthesis 610.0 0 0 0 0 -0.11626374422857776 P38875 0.9539830088615416 0.9587630033493042 0.3076285123825073 0.10476533323526382 52.15060126856172 50.0 0.0 no 5495 chrVIII_485050 17019 essential YHR190W 205 + CTCTCTTTTATTTGATTTTA L|70|V L|70|F silent|CTC>CTG|L|70 silent|CTC>CTT|L|70 ERG9 ERGosterol biosynthesis 444.0 0 0 0 0 0.5383502368455759 P29704 0.7412220239639282 0.032158467918634415 38.442673444605816 20.0 1.0 no 5496 chrVIII_485188r 17023 essential YHR190W 346 - AACGGCTCTGTCCTTCACAT V|122|L V|122|I A|121|P A|121|T ERG9 ERGosterol biosynthesis 444.0 0 1 0 0 -1.189643617878304 P29704 1.0 0.08382125943899155 0.2410816103219986 0.5708795189857483 0.20127999782562256 0.7106599807739258 53.47331671392863 50.0 1.0 no 5497 chrVIII_485576 17031 essential YHR190W 731 + ACAATACGCTCCTCAGTTGA Q|245|E Q|245|* Y|246|* silent|TAC>TAT|Y|246 ERG9 ERGosterol biosynthesis 444.0 0 0 0 0 0.6069906851929899 P29704 0.01224703062325716 48.972699184163844 45.0 1.0 no 5498 chrVIII_485675 17035 essential YHR190W 830 + TATCGATGTGTTGACTTATT I|278|M silent|ATC>ATT|I|278 ERG9 ERGosterol biosynthesis 444.0 0 0 0 0 0.9969436552578492 P29704 0.10140109062194824 0.08686000108718872 40.7493092987022 30.0 1.0 no 5499 chrVIII_485778 17036 essential YHR190W 933 + AACAACCGTGAAGTGCTACA N|312|K silent|AAC>AAT|N|312 N|313|K silent|AAC>AAT|N|313 ERG9 ERGosterol biosynthesis 444.0 0 0 0 0 0.48789591142891997 P29704 0.3464711606502533 0.010311100631952286 44.897862532239685 45.0 1.0 no 5500 chrVIII_485798 17037 essential YHR190W 953 + TGGCAATGTAAAGATTCGTA silent|GGC>GGG|G|319 silent|GGC>GGT|G|319 ERG9 ERGosterol biosynthesis 444.0 0 0 0 0 0.20294291147705595 P29704 39.931381343437295 35.0 1.0 no 5501 chrVIII_491990r 17041 essential YHR196W 62 - TCTTTTGTGCGACGCTTGCT K|27|N silent|AAG>AAA|K|27 UTP9 U Three Protein 575.0 0 0 0 0 -1.0253505315602702 P38882 0.9355990290641784 0.011966681107878685 54.204778668205684 50.0 1.0 no 5502 chrVIII_492109 17042 essential YHR196W 178 + TTTCAGATGTAATCTTCTTT S|61|* S|61|L UTP9 U Three Protein 575.0 0 0 0 0 0.17939392701402573 P38882 0.9298099875450134 0.008782070130109787 39.82080778164675 25.0 1.0 no 5503 chrVIII_492334 17043 essential YHR196W 403 + ACACAGACGAGTCTGATATA T|136|R T|136|I D|135|E silent|GAC>GAT|D|135 UTP9 U Three Protein 575.0 0 0 0 0 -0.6440089665456208 P38882 0.9476869702339172 0.9472420215606691 0.9532920122146606 0.03245136141777038 0.11061527580022812 0.5160666704177856 42.37725188251017 40.0 1.0 no 5504 chrVIII_492470 17044 essential YHR196W 539 + GCACCAAAATGGCACTTTAT H|181|Q silent|CAC>CAT|H|181 H|181|D H|181|Y UTP9 U Three Protein 575.0 0 0 0 0 -0.03951515472634515 P38882 0.9588389992713928 0.9473130106925964 0.9489949941635132 0.4055801331996918 0.22926297783851626 0.10700732469558716 44.79046051792113 40.0 1.0 no 5505 chrVIII_492473r 17046 essential YHR196W 545 - ATACCAATAAAGTGCCATTT V|188|L V|188|I L|187|F silent|TTG>TTA|L|187 UTP9 U Three Protein 575.0 0 0 0 0 -1.1974373183998006 P38882 0.9539830088615416 0.9574310183525084 0.9587849974632264 1.0 0.5000449419021606 0.6250943541526794 41.31502741039503 30.0 1.0 no 5506 chrVIII_492625r 17047 essential YHR196W 697 - AGCTATTAATTCTTCGTTGT A|239|P A|239|T UTP9 U Three Protein 575.0 0 0 0 0 -0.6936483344585646 P38882 0.9573720097541808 0.9523990154266356 0.029207488521933563 0.08932895958423615 43.16513720490253 30.0 1.0 no 5507 chrVIII_492834r 17052 essential YHR196W 906 - ACCTGTTGCTTGCTGTTTAT Q|308|H silent|CAG>CAA|Q|308 V|309|L V|309|I UTP9 U Three Protein 575.0 0 0 0 0 -0.8570854052617644 P38882 0.9570760130882264 0.9539830088615416 0.9574310183525084 0.14686016738414764 0.6711323261260986 0.4444058239459992 52.17301075519526 40.0 1.0 no 5508 chrVIII_492847 17053 essential YHR196W 916 + AGCAACAGGTTCTAATTTCA Q|307|E Q|307|* Q|308|E Q|308|* UTP9 U Three Protein 575.0 0 0 0 0 0.4133853745187869 P38882 0.9590039849281312 0.9590039849281312 0.9453784823417664 43.24145709297829 35.0 1.0 no 5509 chrVIII_494114 17056 essential YHR197W 218 + GACTTGCGCCTATAATCCAC T|74|S T|74|I C|75|W silent|TGC>TGT|C|75 RIX1 RIbosome eXport 763.0 0 0 0 0 0.6102246557664917 P38883 0.9491789937019348 0.9472420215606691 0.9286419749259948 0.02472114562988281 1.0 0.0 50.730838657624595 50.0 1.0 no 5510 chrVIII_494165 17058 essential YHR197W 269 + TGCTGCCATTTATTCCAGAT A|91|G A|91|V A|92|G A|92|V RIX1 RIbosome eXport 763.0 0 0 0 0 0.2926160541375189 P38883 0.9484469890594482 0.9504740238189696 0.9484469890594482 0.9504740238189696 0.5504270195960999 0.2583480179309845 0.1972937285900116 1.0 51.12880119331828 40.0 1.0 no 5511 chrVIII_494211 17061 essential YHR197W 315 + TCGGTTATTTCTTCATCACA S|106|W S|106|L RIX1 RIbosome eXport 763.0 0 0 0 0 0.6516361690153336 P38883 0.9288619756698608 0.9298099875450134 0.01125688385218382 0.0770021378993988 46.06584869990098 35.0 1.0 no 5512 chrVIII_494315 17063 essential YHR197W 419 + AGCACTGGTTCCCAAATTAA A|141|G A|141|V L|142|V silent|CTG>TTG|L|142 RIX1 RIbosome eXport 763.0 0 0 0 0 0.11691508262944572 P38883 0.9484469890594482 0.9504740238189696 0.9512209892272948 0.7146396636962891 0.3501669466495514 0.0 46.69129844786824 40.0 1.0 no 5513 chrVIII_494391r 17065 essential YHR197W 498 - TTCAATATCCTCTGTAGTAC L|172|F silent|TTG>TTA|L|172 RIX1 RIbosome eXport 763.0 0 0 0 0 0.43561898912858776 P38883 0.9587849974632264 0.0 43.53105397904733 35.0 1.0 no 5514 chrVIII_494658 17068 essential YHR197W 762 + AAGCCCATAATTCAATTATG P|256|A P|256|S P|256|R P|256|L RIX1 RIbosome eXport 763.0 0 0 0 0 -0.37784215543088817 P38883 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.06489799171686172 0.20361489057540894 0.01604669913649559 0.01081582345068455 39.50558952202322 30.0 1.0 no 5515 chrVIII_494661r 17069 essential YHR197W 768 - TCTCCACATAATTGAATTAT G|262|A G|262|E E|263|Q E|263|K RIX1 RIbosome eXport 763.0 0 0 0 0 -0.05155548610279044 P38883 0.9499930143356324 0.9438679814338684 0.956179976463318 0.9475290179252625 0.11260977387428285 0.08237398415803909 0.0 0.0 37.765279801212394 25.0 1.0 no 5516 chrVIII_494794 17071 essential YHR197W 898 + TCAACGCACCTTTAACTTTA F|300|L silent|TTC>TTT|F|300 N|301|K silent|AAC>AAT|N|301 RIX1 RIbosome eXport 763.0 0 0 0 0 0.30616349040520136 P38883 0.9387490153312684 0.9439849853515624 0.7742336392402649 0.0 43.51396025784475 35.0 1.0 no 5517 chrVIII_494822 17072 essential YHR197W 926 + TCCACAACGTTTGTCCTTAT P|310|R P|310|L P|310|A P|310|S RIX1 RIbosome eXport 763.0 0 0 0 0 -0.3695937842130768 P38883 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.12755152583122253 0.08691953122615814 0.7277904748916626 0.7526528835296631 49.07572534374401 40.0 1.0 no 5518 chrVIII_494836r 17074 essential YHR197W 943 - AACAAGCATGTCAGCCAATA V|321|L V|321|I M|319|I M|319|I RIX1 RIbosome eXport 763.0 0 0 0 0 0.33333768221630466 P38883 0.9539830088615416 0.9574310183525084 0.9553959965705872 0.9553959965705872 0.6865430474281311 0.7516152858734131 0.0501030758023262 0.0501030758023262 44.56921576709874 40.0 1.0 no 5519 chrVIII_494881r 17077 essential YHR197W 988 - CAGCGGAACTCGAATGGGAA silent|CCG>CCC|P|335 silent|CCG>CCA|P|335 RIX1 RIbosome eXport 763.0 0 0 0 0 0.9620743044467746 P38883 46.014805950894576 55.00000000000001 1.0 no 5520 chrVIII_494883 17078 essential YHR197W 987 + TTTCCCATTCGAGTTCCGCT P|331|A P|331|S P|331|R P|331|L RIX1 RIbosome eXport 763.0 0 0 0 0 0.044007275154110216 P38883 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.4175979197025299 0.09515747427940367 0.03635350987315178 0.028640115633606914 57.33302546448266 50.0 1.0 no 5521 chrVIII_494887r 17081 essential YHR197W 994 - ACCACCCAGCGGAACTCGAA G|338|R G|338|S G|338|A G|338|D RIX1 RIbosome eXport 763.0 0 0 0 0 -0.022165675601440227 P38883 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.4491500854492188 0.7006101608276367 1.0 0.5430353879928589 54.00264981423072 60.0 1.0 no 5522 chrVIII_495078 17082 essential YHR197W 1182 + TGCGGTTTATCATTTTTCGA C|395|W silent|TGC>TGT|C|395 RIX1 RIbosome eXport 763.0 0 0 0 0 -0.5610716941746976 P38883 0.9286419749259948 0.18645210564136505 45.73556535902702 35.0 1.0 no 5523 chrVIII_495551 17086 essential YHR197W 1655 + CACGCAATCTTTAAGATTAA T|553|R T|553|M Q|554|E Q|554|* RIX1 RIbosome eXport 763.0 0 0 0 0 0.4157907933754485 P38883 0.9476869702339172 0.9502379894256592 0.9590039849281312 0.3887860476970673 0.24346333742141724 0.8015282154083252 37.004902543962935 30.0 1.0 no 5524 chrIX_61549 17088 essential YIL150C 1160 - GTCTTTCCTCCTCTTCTGAC R|393|T R|393|K E|392|Q E|392|K MCM10 MiniChromosome Maintenance 571.0 0 0 0 0 1.2413193784164789 P32354 0.979092001914978 0.9988390207290648 1.0004899501800537 0.9891330003738404 0.5695562362670898 0.9709606170654296 0.18982185423374176 0.18129274249076846 57.125869941911105 50.0 0.0 no 5525 chrIX_61606 17090 essential YIL150C 1103 - TTTCCCCTTTGGCCTTATAT E|374|Q E|374|K silent|GGG>GGC|G|373 silent|GGG>GGA|G|373 MCM10 MiniChromosome Maintenance 571.0 0 0 0 0 -2.461723845747448 P32354 1.0004899501800537 0.9891330003738404 0.575544536113739 0.9301472902297974 55.23687903749948 40.0 0.0 yes 5526 chrIX_61705 17095 essential YIL150C 1004 - CACGAAATTGCACTTCTCTA R|341|P R|341|H MCM10 MiniChromosome Maintenance 571.0 0 0 0 0 0.3859602989429369 P32354 0.960108995437622 1.0001100301742554 0.0 0.0 43.24619639576417 40.0 0.0 no 5527 chrIX_61816 17097 essential YIL150C 893 - CTCTACTTGAACCTATCTCC R|304|T R|304|K S|303|T S|303|N MCM10 MiniChromosome Maintenance 571.0 0 0 0 0 -0.5744830320618939 P32354 0.900963008403778 0.9193329811096193 0.9219859838485718 0.9260370135307312 0.024835607036948204 1.0 0.0 0.0 48.72946378644292 45.0 0.0 no 5528 chrIX_61985r 17101 essential YIL150C 721 + CACTAGATGTTTATATCTTC L|242|V silent|CTA>TTA|L|242 MCM10 MiniChromosome Maintenance 571.0 0 0 0 0 -0.3485800580483181 P32354 0.9282950162887572 0.5122858285903931 39.1090758054832 30.0 0.0 no 5529 chrIX_62321 17107 essential YIL150C 388 - ATTCATCATGCTTTCAAACT M|135|I M|135|I M|134|I M|134|I MCM10 MiniChromosome Maintenance 571.0 0 1 0 0 0.22323800677051284 P32354 0.9307159781455994 0.9307159781455994 0.9314879775047302 0.9314879775047302 0.0673137754201889 0.0673137754201889 0.14846153557300568 0.14846153557300568 41.57091874956893 30.0 0.0 no 5530 chrIX_62256 17108 essential YIL150C 453 - TCTAATTCGTTTGTGATTAT E|158|Q E|158|K MCM10 MiniChromosome Maintenance 571.0 0 0 0 0 0.8022318331907224 P32354 0.9202449917793274 0.9081959724426271 0.0 0.0 38.79753059513661 25.0 0.0 no 5531 chrIX_62481r 17110 essential YIL150C 225 + TCTCATAATGCTACACAACA H|77|D H|77|Y S|76|C S|76|F MCM10 MiniChromosome Maintenance 571.0 0 0 0 0 0.37879922961187695 P32354 0.9917020201683044 0.9918540120124816 0.9879119992256165 0.9685909748077391 0.6378538012504578 0.3992551565170288 0.05718991905450821 0.06604722887277603 41.0183230453984 35.0 0.0 no 5532 chrIX_70781 17119 essential YIL147C 2653 - GCCAGTACCACCATATTGCC G|891|R G|891|S G|891|A G|891|D SLN1 Synthetic Lethal of N-end rule 1220.0 0 0 0 0 -6.452045577198397 P39928 0.0 0.0 0.0 0.0 58.023305278887385 55.00000000000001 0.0 yes 5533 chrIX_70959r 17123 essential YIL147C 2472 + AGTCAGTTCAATAAAGCACC Q|826|E Q|826|* SLN1 Synthetic Lethal of N-end rule 1220.0 0 0 0 0 -0.2283147936892481 P39928 0.09704795479774476 43.43794276352725 40.0 0.0 no 5534 chrIX_71332 17127 essential YIL147C 2102 - CATCAACGGTACCATCTACA D|707|H D|707|N V|706|L V|706|I SLN1 Synthetic Lethal of N-end rule 1220.0 0 0 0 0 -0.481799415046132 P39928 0.1506844460964203 0.8025687336921692 0.0295088030397892 0.1413823813199997 46.84720887162069 45.0 0.0 no 5535 chrIX_71333 17128 essential YIL147C 2101 - ATCAACGGTACCATCTACAG D|707|H D|707|N V|706|L V|706|I SLN1 Synthetic Lethal of N-end rule 1220.0 0 0 0 0 0.4175661549719635 P39928 0.1506844460964203 0.8025687336921692 0.0295088030397892 0.1413823813199997 45.676737997854396 45.0 0.0 no 5536 chrIX_71424 17130 essential YIL147C 2010 - ACCATTGTCCTTATCAAATT M|676|I M|676|I V|677|L V|677|I SLN1 Synthetic Lethal of N-end rule 1220.0 0 0 0 0 0.7093140829553555 P39928 0.049267664551734924 0.049267664551734924 0.1561311036348343 0.2045112252235413 43.49799690823129 30.0 0.0 no 5537 chrIX_71493r 17131 essential YIL147C 1938 + TTACAAATAAAATCGATATT Q|648|E Q|648|* SLN1 Synthetic Lethal of N-end rule 1220.0 0 0 0 0 -0.031043937919345288 P39928 0.0 28.128555245323128 15.0 0.0 no 5538 chrIX_71593r 17132 essential YIL147C 1838 + GCTTTTGCTTCATATTCTAA L|614|V L|614|F SLN1 Synthetic Lethal of N-end rule 1220.0 0 0 0 0 0.8170730181717656 P39928 0.0 0.0 43.900113890443954 30.0 0.0 no 5539 chrIX_71695r 17134 essential YIL147C 1736 + AACGCCTTTAAATGGTATTC T|580|R T|580|M P|581|A P|581|S SLN1 Synthetic Lethal of N-end rule 1220.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.4210992066132256 P39928 0.0 0.0 0.0 0.0 41.45199839466079 35.0 0.0 no 5540 chrIX_71717 17135 essential YIL147C 1717 - TCTCAATTCGTGCGAAATAT L|578|F silent|TTG>TTA|L|578 R|579|T R|579|K SLN1 Synthetic Lethal of N-end rule 1220.0 0 1 0 0 0.3734971746313931 P39928 0.0 0.0 0.0 40.615463453801176 35.0 0.0 no 5541 chrIX_72185 17143 essential YIL147C 1249 - TCCATGGCCACTTACGCTTG G|423|R G|423|R G|423|A G|423|E SLN1 Synthetic Lethal of N-end rule 1220.0 0 0 0 0 -0.2756172030555657 P39928 0.6763402223587036 0.6763402223587036 0.697526752948761 0.8755660057067871 55.426593565349435 55.00000000000001 0.0 no 5542 chrIX_72192r 17145 essential YIL147C 1239 + GGCAGCACCACAAGCGTAAG silent|GGC>GGG|G|414 silent|GGC>GGT|G|414 S|415|R silent|AGC>AGT|S|415 SLN1 Synthetic Lethal of N-end rule 1220.0 0 0 0 0 0.8160427837064039 P39928 0.05729915201663971 52.44584299336083 60.0 0.0 no 5543 chrIX_72290 17147 essential YIL147C 1144 - GGCTCTGCTTATCGTTCTTG A|388|P A|388|T R|387|T R|387|K SLN1 Synthetic Lethal of N-end rule 1220.0 0 0 0 0 -0.21658640975931914 P39928 0.2886218726634979 0.6236224770545961 0.24809905886650085 1.0 53.685270975873145 50.0 0.0 no 5544 chrIX_72289 17148 essential YIL147C 1145 - TGGCTCTGCTTATCGTTCTT A|388|P A|388|T R|387|T R|387|K SLN1 Synthetic Lethal of N-end rule 1220.0 0 0 0 0 -0.8297640210989543 P39928 0.2886218726634979 0.6236224770545961 0.24809905886650085 1.0 53.685270975873145 45.0 0.0 no 5545 chrIX_72553 17162 essential YIL147C 881 - AAGCAGTATTCCGTGTAGAA A|300|P A|300|T SLN1 Synthetic Lethal of N-end rule 1220.0 0 0 0 0 -1.7363769890411904 P39928 0.014231353998184202 0.019170651212334636 45.31466384651225 40.0 0.0 no 5546 chrIX_72563r 17165 essential YIL147C 868 + AAACCAATATCCTTTCTACA T|291|S T|291|I silent|ACC>ACG|T|291 silent|ACC>ACT|T|291 SLN1 Synthetic Lethal of N-end rule 1220.0 0 0 0 0 0.13817850693752295 P39928 0.2111707180738449 0.3790983557701111 41.133028225830905 30.0 0.0 no 5547 chrIX_72601r 17166 essential YIL147C 830 + TAGCGCATTTAGAAACGGGA S|278|R silent|AGC>AGT|S|278 A|279|G A|279|V SLN1 Synthetic Lethal of N-end rule 1220.0 0 0 0 0 0.39593386881602055 P39928 0.4548205733299256 0.03894353657960892 0.4439739286899567 44.466988445092 45.0 0.0 no 5548 chrIX_72801r 17169 essential YIL147C 630 + ACTATAATAATGTCGGCAGA T|211|S T|211|I SLN1 Synthetic Lethal of N-end rule 1220.0 0 0 0 0 -0.2408266915702368 P39928 0.14904507994651794 0.0050603742711246005 40.32509365032377 35.0 0.0 no 5549 chrIX_72848 17171 essential YIL147C 586 - AGTCAAGATAATAGAAGGAT L|201|F silent|TTG>TTA|L|201 SLN1 Synthetic Lethal of N-end rule 1220.0 0 0 0 0 0.18226481302020764 P39928 0.4725068211555481 34.71937517605073 30.0 0.0 no 5550 chrIX_72884 17172 essential YIL147C 550 - AGACATAGACATCAAATAGT M|189|I M|189|I SLN1 Synthetic Lethal of N-end rule 1220.0 0 0 0 0 -0.5394174188999821 P39928 0.042023170739412315 0.042023170739412315 36.04482809232542 30.0 0.0 no 5551 chrIX_72946r 17175 essential YIL147C 485 + TACACCGCTACCTTCTTCAC T|163|R T|163|I P|164|A P|164|S SLN1 Synthetic Lethal of N-end rule 1220.0 0 0 0 0 -0.11376191830427558 P39928 0.5147030949592589 0.20489417016506195 0.4434391260147095 0.8025901913642883 52.87130916542271 50.0 0.0 no 5552 chrIX_72987 17178 essential YIL147C 447 - AAACTGTCTAAAACATCTTC S|155|T S|155|N SLN1 Synthetic Lethal of N-end rule 1220.0 0 0 0 0 0.4179257008719202 P39928 0.20719271898269653 0.1809147149324417 34.91484508104509 30.0 0.0 no 5553 chrIX_73158r 17181 essential YIL147C 273 + TCACTAACAAGTTACGTTGC L|93|V silent|CTA>TTA|L|93 S|92|* S|92|L SLN1 Synthetic Lethal of N-end rule 1220.0 0 0 0 0 0.0062385214994781215 P39928 0.13513486087322235 0.06936071068048477 42.39239662512245 40.0 0.0 no 5554 chrIX_73292r 17185 essential YIL147C 139 + CCTCGAACTATAAAAATTTA S|48|W S|48|L silent|ACC>ACG|T|47 silent|ACC>ACT|T|47 SLN1 Synthetic Lethal of N-end rule 1220.0 0 0 0 0 -0.2386904234703004 P39928 0.059860914945602424 0.3167009949684143 33.54596874532757 25.0 0.0 no 5555 chrIX_73381r 17187 essential YIL147C 50 + AGGCATCCGAACTCAACTAA silent|GGC>GGG|G|18 silent|GGC>GGT|G|18 I|19|M silent|ATC>ATT|I|19 SLN1 Synthetic Lethal of N-end rule 1220.0 0 0 0 0 -0.01979763471075061 P39928 0.051281299442052834 45.538562641106815 45.0 0.0 no 5556 chrIX_73401r 17188 essential YIL147C 30 + CTCACTCCTCCGTTTAGGAT silent|CTC>CTG|L|11 silent|CTC>CTT|L|11 T|12|S T|12|I SLN1 Synthetic Lethal of N-end rule 1220.0 0 0 0 0 1.1986127195695295 P39928 0.3799438178539276 0.042697492986917496 -0.3228600025177002 -0.24167999625205994 54.601485477799095 50.0 0.0 no 5557 chrIX_78097 17190 essential YIL144W 23 + TCAACATGTGCTACATCACA Q|9|E Q|9|* H|10|D H|10|Y NDC80 Nuclear Division Cycle 691.0 0 1 0 0 -2.069762163295677 P40460 0.9590039849281312 0.9473130106925964 0.9489949941635132 1.0 0.9899479150772096 0.2328377366065979 45.002011348028134 40.0 1.0 yes 5558 chrIX_78108 17191 essential YIL144W 34 + TACATCACATGGACCCTCAT H|13|D H|13|Y H|14|D H|14|Y NDC80 Nuclear Division Cycle 691.0 0 0 0 0 0.6454571184167774 P40460 0.9473130106925964 0.9489949941635132 0.9473130106925964 0.9489949941635132 0.8027475476264954 0.08450576663017273 0.6724691987037659 0.1870105117559433 50.19579708193015 45.0 1.0 no 5559 chrIX_78139r 17192 essential YIL144W 68 - ACGATGTTGCAGTTGGTATT silent|TCG>TCC|S|29 silent|TCG>TCA|S|29 NDC80 Nuclear Division Cycle 691.0 0 0 0 0 -1.6166612250328762 P40460 47.39880132346076 40.0 1.0 no 5560 chrIX_78150 17193 essential YIL144W 76 + CTGCAACATCGTCACAATTG A|27|G A|27|V T|28|R T|28|I NDC80 Nuclear Division Cycle 691.0 0 1 0 0 -0.2593416149398682 P40460 0.9484469890594482 0.9504740238189696 0.9476869702339172 0.9472420215606691 0.5485818982124329 0.2881042957305908 0.5342298746109009 0.2403454482555389 43.80740673109813 45.0 1.0 no 5561 chrIX_78342r 17196 essential YIL144W 271 - GCTGACGCTGTTTCTACTGT S|97|T S|97|N V|96|L V|96|I NDC80 Nuclear Division Cycle 691.0 0 1 0 0 0.6482664599375647 P40460 0.9512869715690612 0.9536849856376648 0.9539830088615416 0.9574310183525084 0.7244283556938171 0.5765596628189087 0.6869128346443176 0.4228864014148712 53.524507177813575 50.0 1.0 no 5562 chrIX_78402 17198 essential YIL144W 328 + ATCTGAGCAATAGAGATCCA L|111|V silent|CTG>TTG|L|111 NDC80 Nuclear Division Cycle 691.0 0 0 0 0 0.6147423715238497 P40460 0.9512209892272948 0.4991919100284576 44.856997081706886 40.0 1.0 no 5563 chrIX_78532 17201 essential YIL144W 458 + TCTAAAACAACCCACTCAAA L|154|V silent|CTA>TTA|L|154 NDC80 Nuclear Division Cycle 691.0 0 0 0 0 0.6269794898477401 P40460 0.9512209892272948 0.0 39.00877934285711 35.0 1.0 no 5564 chrIX_78874 17209 essential YIL144W 800 + ACAAGAAAGATATGAGCTAA Q|268|E Q|268|* NDC80 Nuclear Division Cycle 691.0 0 0 0 0 0.8220520024569136 P40460 0.9590039849281312 0.0413426011800766 33.83435259539755 30.0 1.0 no 5565 chrIX_78968r 17210 essential YIL144W 897 - AACTTTAGTTCTTGCATCGA K|305|N silent|AAG>AAA|K|305 NDC80 Nuclear Division Cycle 691.0 0 0 0 0 -0.3969844732384311 P40460 0.9355990290641784 0.4775632917881012 44.221871129755705 35.0 1.0 no 5566 chrIX_79093 17215 essential YIL144W 1019 + CCAAAAGATCAAAACCACCA Q|341|E Q|341|* NDC80 Nuclear Division Cycle 691.0 0 1 0 0 -0.057256478961921986 P40460 0.9590039849281312 1.0 40.78779215939449 40.0 1.0 no 5567 chrIX_79254r 17218 essential YIL144W 1183 - TTCGGAAATATTACTTTGTA E|401|Q E|401|K NDC80 Nuclear Division Cycle 691.0 0 0 0 0 0.5283249328523268 P40460 0.956179976463318 0.9475290179252625 0.23052148520946505 0.5755730271339417 36.48810035286692 25.0 1.0 no 5568 chrIX_79196r 17219 essential YIL144W 1125 - TTCATCTTTTCCAGTTTACC M|381|I M|381|I K|380|N silent|AAG>AAA|K|380 NDC80 Nuclear Division Cycle 691.0 0 0 0 0 -0.4955161640542406 P40460 0.9553959965705872 0.9553959965705872 0.9355990290641784 0.1668049693107605 0.1668049693107605 0.02854070626199245 48.59690931842704 35.0 1.0 no 5569 chrIX_79221r 17220 essential YIL144W 1150 - TTCTTCTTTCAGTTCACACT E|390|Q E|390|K E|389|Q E|389|K NDC80 Nuclear Division Cycle 691.0 0 0 0 0 0.2026359000416937 P40460 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.6159306168556213 0.8982800841331482 0.5943602919578552 1.0 47.663576936252404 35.0 1.0 no 5570 chrIX_79409 17223 essential YIL144W 1335 + TCCAGAAAGCTGGAAGCCGA silent|TCC>TCG|S|446 silent|TCC>TCT|S|446 S|446|C S|446|F NDC80 Nuclear Division Cycle 691.0 0 0 0 0 -0.329022725543227 P40460 0.945252001285553 0.9294660091400146 0.015366794541478157 0.012687521055340769 50.61925267879406 55.00000000000001 1.0 no 5571 chrIX_79490 17224 essential YIL144W 1416 + ACCAGATCGCGTAGTCAATT silent|ACC>ACG|T|473 silent|ACC>ACT|T|473 T|473|S T|473|I NDC80 Nuclear Division Cycle 691.0 0 0 0 0 1.0047485123411273 P40460 0.9491789937019348 0.9472420215606691 0.03736376389861107 0.6942727565765381 48.6425035539159 45.0 1.0 no 5572 chrIX_81179 17226 essential YIL143C 1843 - TTTCAAAGCATATTCTTGTA L|620|F silent|TTG>TTA|L|620 SSL2 Suppressor of Stem-Loop mutation 843.0 0 0 0 0 1.1680000387840328 Q00578 0.9587849974632264 0.7205430865287781 0.44381383061409 38.63186123849732 25.0 0.0 no 5573 chrIX_81237r 17227 essential YIL143C 1782 + ATTCAATATCACGAAAGGAG Q|596|E Q|596|* SSL2 Suppressor of Stem-Loop mutation 843.0 0 0 0 0 0.040032667242275 Q00578 0.9590039849281312 0.5831816792488098 36.21038763022728 35.0 0.0 no 5574 chrIX_81364 17228 essential YIL143C 1658 - GACACCAAACCTCTGCACAT C|559|S C|559|Y W|558|C W|558|* SSL2 Suppressor of Stem-Loop mutation 843.0 0 0 0 0 -1.8772449680495438 Q00578 0.9421560168266296 0.9290120005607604 0.8858469724655151 0.004706802312284708 0.003798358608037234 0.0011078849202021956 1.7136019468307495 7.27389669418335 3.6946988105773926 49.96346871815342 50.0 0.0 no 5575 chrIX_81479 17230 essential YIL143C 1543 - ATCTTCTCTAACCAGCGTTG D|521|H D|521|N E|520|Q E|520|K SSL2 Suppressor of Stem-Loop mutation 843.0 0 0 0 0 -6.610665757188753 Q00578 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.0 0.0 0.0 0.0 49.19060737029843 45.0 0.0 yes 5576 chrIX_81507r 17231 essential YIL143C 1512 + ATCGCAGCACACGCCAAATT I|505|M silent|ATC>ATT|I|505 A|506|G A|506|V SSL2 Suppressor of Stem-Loop mutation 843.0 0 0 0 0 -0.27401428817934315 Q00578 0.9598389863967896 0.9484469890594482 0.9504740238189696 0.033138446509838104 0.05739269778132439 0.04302743822336197 50.19645492590558 50.0 0.0 no 5577 chrIX_81508r 17232 essential YIL143C 1511 + CATCGCAGCACACGCCAAAT I|505|M silent|ATC>ATT|I|505 A|506|G A|506|V SSL2 Suppressor of Stem-Loop mutation 843.0 0 0 0 0 0.8622943890939659 Q00578 0.9598389863967896 0.9484469890594482 0.9504740238189696 0.033138446509838104 0.05739269778132439 0.04302743822336197 51.05936454878349 55.00000000000001 0.0 no 5578 chrIX_81619r 17236 essential YIL143C 1400 + TCATGATTCACAAAAAGTTA H|468|D H|468|Y SSL2 Suppressor of Stem-Loop mutation 843.0 0 0 0 0 0.7593667217773745 Q00578 0.9473130106925964 0.9489949941635132 0.21082274615764615 1.0 33.82233779622709 25.0 0.0 no 5579 chrIX_81685r 17238 essential YIL143C 1334 + GTTCCAGACAGAATCCGGTT F|446|L silent|TTC>TTT|F|446 Q|447|E Q|447|* SSL2 Suppressor of Stem-Loop mutation 843.0 0 0 0 0 -1.092900611382812 Q00578 0.9387490153312684 0.9590039849281312 1.0 1.0 52.080331116192504 50.0 0.0 no 5580 chrIX_81704 17239 essential YIL143C 1318 - GAACATTTCCTTATTATCAG M|445|I M|445|I SSL2 Suppressor of Stem-Loop mutation 843.0 0 0 0 0 -1.106381802082825 Q00578 0.9553959965705872 0.9553959965705872 0.4378684461116791 0.4378684461116791 39.58157088077968 30.0 0.0 no 5581 chrIX_82064 17243 essential YIL143C 958 - TACGACTTCAACAGACTCAT V|326|L V|326|I V|325|L V|325|I SSL2 Suppressor of Stem-Loop mutation 843.0 0 0 0 0 0.10482576846299646 Q00578 0.9539830088615416 0.9574310183525084 0.9539830088615416 0.9574310183525084 0.15212035179138186 0.0730033740401268 0.29829081892967224 0.1864340901374817 42.51627326810552 40.0 0.0 no 5582 chrIX_82148 17244 essential YIL143C 874 - ACCTATAACTGCACTAAACA G|298|R G|298|S G|298|A G|298|D SSL2 Suppressor of Stem-Loop mutation 843.0 0 0 0 0 0.006952378675240109 Q00578 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.5387351512908936 0.7532116770744324 0.7758274078369141 0.6467976570129395 40.69350309923875 35.0 0.0 no 5583 chrIX_82209r 17248 essential YIL143C 810 + CAACAACTTCAGCAAACCGC Q|272|E Q|272|* L|273|V L|273|F SSL2 Suppressor of Stem-Loop mutation 843.0 0 0 0 0 -0.2220109190300885 Q00578 0.9590039849281312 0.9512209892272948 0.9587849974632264 1.0 0.3442565500736237 0.14164330065250394 45.15533051559839 50.0 0.0 no 5584 chrIX_82286r 17251 essential YIL143C 733 + TGCTGAATGATTCCGTCATC L|246|V silent|CTG>TTG|L|246 SSL2 Suppressor of Stem-Loop mutation 843.0 0 0 0 0 0.32123528594772344 Q00578 0.9512209892272948 0.03528503328561783 47.645702694667136 45.0 0.0 no 5585 chrIX_82287r 17252 essential YIL143C 732 + TTGCTGAATGATTCCGTCAT L|246|V silent|CTG>TTG|L|246 SSL2 Suppressor of Stem-Loop mutation 843.0 0 0 0 0 -0.11799372737757685 Q00578 0.9512209892272948 0.03528503328561783 46.89292682238431 40.0 0.0 no 5586 chrIX_82370 17253 essential YIL143C 652 - TTTCACTTTACCGTATGAAA silent|GTG>GTC|V|223 silent|GTG>GTA|V|223 V|223|L V|223|M SSL2 Suppressor of Stem-Loop mutation 843.0 0 0 0 0 -0.29108440955035986 Q00578 0.9539830088615416 0.9587630033493042 0.02447453700006008 0.007215846795588731 40.20282603043569 30.0 0.0 no 5587 chrIX_82643r 17262 essential YIL143C 376 + ACCATGCTTCCAGGCCCCTT H|127|D H|127|Y D|126|E silent|GAC>GAT|D|126 SSL2 Suppressor of Stem-Loop mutation 843.0 0 0 0 0 -0.5327084291655594 Q00578 0.9473130106925964 0.9489949941635132 0.9532920122146606 0.08276046812534332 0.029444819316267967 0.02379260025918484 65.52324079839696 60.0 0.0 no 5588 chrIX_82675 17263 essential YIL143C 347 - ACCGCAAATAACTAAAGTCA R|122|P R|122|Q silent|CGG>CGC|R|122 silent|CGG>CGA|R|122 SSL2 Suppressor of Stem-Loop mutation 843.0 0 0 0 0 0.28416949944013425 Q00578 0.9099509716033936 0.949662983417511 0.3168323636054993 0.5797886252403259 38.91525546412197 35.0 0.0 no 5589 chrIX_82676r 17264 essential YIL143C 343 + GCCATGACTTTAGTTATTTG H|116|D H|116|Y S|115|R silent|AGC>AGT|S|115 SSL2 Suppressor of Stem-Loop mutation 843.0 0 0 0 0 -1.0069262242773172 Q00578 0.9473130106925964 0.9489949941635132 0.9417110085487366 0.07884208858013153 0.06644274294376372 0.5386167168617249 44.26557514344245 35.0 0.0 no 5590 chrIX_82710r 17265 essential YIL143C 309 + TTCGTTCCAGATTCCGTCTC F|104|L silent|TTC>TTT|F|104 P|106|A P|106|S SSL2 Suppressor of Stem-Loop mutation 843.0 0 0 0 0 -0.17545384966911262 Q00578 0.9387490153312684 0.9562489986419678 0.9498909711837769 0.6466220021247864 0.7357245683670044 0.7083868980407715 54.79521336285183 50.0 0.0 no 5591 chrIX_82697 17267 essential YIL143C 325 - GCTTCTGAACATTCCAGAGA S|115|T S|115|N R|114|T R|114|K SSL2 Suppressor of Stem-Loop mutation 843.0 0 0 0 0 -0.8149234360011606 Q00578 0.9512869715690612 0.9536849856376648 0.932735025882721 0.955805003643036 0.5910941958427429 0.5077306032180786 0.4626960158348084 1.0 48.197114933166525 45.0 0.0 no 5592 chrIX_82847 17270 essential YIL143C 175 - CTTCTTCAACCCTGTTACCA K|64|N silent|AAG>AAA|K|64 L|63|F silent|TTG>TTA|L|63 SSL2 Suppressor of Stem-Loop mutation 843.0 0 0 0 0 0.08903409195327205 Q00578 0.9355990290641784 0.9587849974632264 0.4961528182029724 0.1594671607017517 52.778710305487486 45.0 0.0 no 5593 chrIX_82824 17271 essential YIL143C 198 - CTACTCTTGGTCTTTTTCCG S|72|T S|72|N K|71|N silent|AAG>AAA|K|71 SSL2 Suppressor of Stem-Loop mutation 843.0 0 0 0 0 -0.6878607255759002 Q00578 0.9512869715690612 0.9536849856376648 0.9355990290641784 0.5663496255874634 0.4902657866477966 0.43571215867996216 50.868123945521745 45.0 0.0 no 5594 chrIX_83003r 17278 essential YIL143C 16 + GCTACCAACCTAAGAGCAAG silent|GGC>GGG|G|6 silent|GGC>GGT|G|6 Y|7|* silent|TAC>TAT|Y|7 SSL2 Suppressor of Stem-Loop mutation 843.0 0 0 0 0 0.04906948957202797 Q00578 46.93555249092202 50.0 0.0 no 5595 chrIX_83354r 17283 essential YIL142W 55 - ACCGACAAACGCCGACAAAC G|25|R G|25|S G|25|A G|25|D CCT2 Chaperonin Containing TCP-1 527.0 0 0 0 0 -0.8371780355056522 P39076 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.004061510320752859 0.012817553244531156 0.01827654056251049 0.01325997058302164 7.709000110626222 1.8760000467300413 -1.0609999895095823 7.065599918365479 6.9079999923706055 2.5420000553131104 1.0399999618530271 5.22599983215332 45.27119815562338 55.00000000000001 1.0 no 5596 chrIX_83445 17285 essential YIL142W 143 + TGCGTCCAGTAACACTTGCA A|49|G A|49|V S|50|C S|50|F CCT2 Chaperonin Containing TCP-1 527.0 0 1 0 0 -0.5509215687415939 P39076 0.9484469890594482 0.9504740238189696 0.945252001285553 0.9294660091400146 0.4302144348621368 0.27842745184898376 0.040954049676656716 0.038216106593608856 0.19200000166893005 0.16599999368190765 0.06620000302791595 -0.9965999722480774 0.8528800010681152 0.9626399874687196 -0.19220000505447388 0.02359999716281891 52.38802335845514 50.0 1.0 no 5597 chrIX_83515r 17286 essential YIL142W 216 - TTCACCAACACTTTGGCTGC silent|GTG>GTC|V|78 silent|GTG>GTA|V|78 V|78|L V|78|M CCT2 Chaperonin Containing TCP-1 527.0 0 0 0 0 0.6062330454398597 P39076 0.9539830088615416 0.9587630033493042 0.08674166351556778 0.02742666006088257 1.9279999732971191 0.4005999863147736 51.83249559829852 50.0 1.0 no 5598 chrIX_83516r 17287 essential YIL142W 217 - GTTCACCAACACTTTGGCTG silent|GTG>GTC|V|78 silent|GTG>GTA|V|78 V|78|L V|78|M CCT2 Chaperonin Containing TCP-1 527.0 0 0 0 0 1.3240323812244272 P39076 0.9539830088615416 0.9587630033493042 0.08674166351556778 0.02742666006088257 1.9279999732971191 0.4005999863147736 50.77413956781891 50.0 1.0 no 5599 chrIX_83522r 17288 essential YIL142W 223 - ACTGATGTTCACCAACACTT S|81|T S|81|N CCT2 Chaperonin Containing TCP-1 527.0 0 1 0 0 0.07769712197582762 P39076 0.9512869715690612 0.9536849856376648 0.03677451983094216 0.008475036360323429 1.9084000587463381 3.947200059890747 46.11139434649556 40.0 1.0 no 5600 chrIX_83690r 17293 essential YIL142W 391 - TTTCGTTAACGCATCCAATG silent|ACG>ACC|T|136 silent|ACG>ACA|T|136 CCT2 Chaperonin Containing TCP-1 527.0 0 0 0 0 1.1034680566905026 P39076 43.97739038243196 40.0 1.0 no 5601 chrIX_83911 17296 essential YIL142W 609 + TCAGATTCGTTCCTTGACGA S|204|* S|204|L CCT2 Chaperonin Containing TCP-1 527.0 0 0 0 0 -0.5770997725335593 P39076 0.9298099875450134 0.23395699262619016 0.16979999840259552 48.972699184163844 45.0 1.0 no 5602 chrIX_83994 17298 essential YIL142W 692 + TCTAATCGCCAATACAACTT L|232|V silent|CTA>TTA|L|232 I|233|M silent|ATC>ATT|I|233 CCT2 Chaperonin Containing TCP-1 527.0 0 0 0 0 0.6430281257005966 P39076 0.9512209892272948 0.9598389863967896 0.007209289353340864 0.004609584342688322 2.610599994659424 -0.3206000030040741 41.90846476053434 35.0 1.0 no 5603 chrIX_84002r 17300 essential YIL142W 703 - GTCTGTATCCAAAGTTGTAT D|241|H D|241|N CCT2 Chaperonin Containing TCP-1 527.0 0 1 0 0 -2.32835704995276 P39076 0.9486550092697144 0.956179976463318 0.0 0.0 3.601799964904785 1.3703999519348145 -0.9767000079154968 -1.6345999240875244 44.4060774963786 35.0 1.0 yes 5604 chrIX_84355r 17307 essential YIL142W 1056 - CAACCACTAAACTTCAAGAA G|358|A G|358|D G|358|R G|358|S CCT2 Chaperonin Containing TCP-1 527.0 0 0 0 0 0.11446730931173332 P39076 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.0 0.0 0.0 0.0 1.4678000211715698 1.3833999633789062 1.0585999488830566 1.521399974822998 0.3810000121593475 1.3414000272750854 0.18539999425411224 0.7138000130653381 37.2645026411056 35.0 1.0 no 5605 chrIX_84352 17308 essential YIL142W 1050 + CAGCCATTCTTGAAGTTTAG P|352|A P|352|S P|352|R P|352|L CCT2 Chaperonin Containing TCP-1 527.0 0 0 0 0 -0.20175896263716955 P39076 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.08378972113132477 0.07985746115446091 0.5280799865722656 0.039820540696382516 1.5961999893188477 2.599600076675415 1.9234000444412231 0.9553999900817872 0.7164000272750854 1.163599967956543 0.259799987077713 0.31540000438690186 45.03799755486881 40.0 1.0 no 5606 chrIX_85407 17312 no_effect YIL140W 41 + ATCACTACTCCATCTAGTAG S|15|* S|15|L L|16|V silent|CTA>TTA|L|16 AXL2 AXiaL 2 bud site selection 823.0 0 0 0 0 0.2715827008799278 P38928 0.9298099875450134 0.9512209892272948 0.8133561015129089 0.4299989342689514 46.085751162003874 40.0 1.0 no 5607 chrIX_85436r 17314 no_effect YIL140W 73 - TCCGATAGGATATGCCTCAT G|31|R G|31|R G|31|A G|31|E AXL2 AXiaL 2 bud site selection 823.0 0 0 0 0 -1.1661978645797555 P38928 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.1040235087275505 0.1040235087275505 0.15526658296585086 0.2106265872716904 50.46061536974594 45.0 1.0 no 5608 chrIX_85469r 17316 no_effect YIL140W 106 - TTCATTGACTCTTGCCACTG E|42|Q E|42|K AXL2 AXiaL 2 bud site selection 823.0 0 1 0 0 0.1699409643089179 P38928 0.956179976463318 0.9475290179252625 0.15924420952796936 0.19182339310646054 49.74482886753685 45.0 1.0 no 5609 chrIX_85597 17319 no_effect YIL140W 231 + TCTAGTTCTAGAACGTTCTC S|78|C S|78|F AXL2 AXiaL 2 bud site selection 823.0 0 0 0 0 -0.2073913412460445 P38928 0.945252001285553 0.9294660091400146 0.020650813356041908 0.019871678203344345 44.57186735964007 40.0 1.0 no 5610 chrIX_85761 17324 no_effect YIL140W 395 + ATCGTCAGATTTCAATCTAT S|133|W S|133|L S|134|* S|134|L AXL2 AXiaL 2 bud site selection 823.0 0 0 0 0 -0.6813997468092774 P38928 0.9288619756698608 0.9298099875450134 0.9298099875450134 0.006529982667416334 0.03723766282200813 0.231704980134964 40.97156793220114 30.0 1.0 no 5611 chrIX_86117r 17331 no_effect YIL140W 754 - TATCAAACTATTTTGAATAG L|257|F silent|TTG>TTA|L|257 AXL2 AXiaL 2 bud site selection 823.0 0 1 0 0 0.5498080260056991 P38928 0.9587849974632264 0.04960842803120613 30.28138309261573 20.0 1.0 no 5612 chrIX_86208 17333 no_effect YIL140W 842 + TCCTATTTCTTCTGATAAAT P|282|R P|282|L P|282|A P|282|S AXL2 AXiaL 2 bud site selection 823.0 0 0 0 0 1.5975337087987884 P38928 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.2753045856952667 0.5049583911895752 0.8010635972023009 0.41280820965766907 39.31033742259979 25.0 1.0 no 5613 chrIX_86209 17334 no_effect YIL140W 843 + CCTATTTCTTCTGATAAATT P|282|R P|282|L AXL2 AXiaL 2 bud site selection 823.0 0 0 0 0 0.9321287309297204 P38928 0.9432820081710817 0.9430609941482544 0.2753045856952667 0.5049583911895752 38.683452099148326 25.0 1.0 no 5614 chrIX_86240 17335 no_effect YIL140W 874 + ACTTATTGGATGCTCCAGAC N|292|K silent|AAC>AAT|N|292 AXL2 AXiaL 2 bud site selection 823.0 0 0 0 0 -0.8812759212780774 P38928 0.9439849853515624 0.9065594673156738 48.462091624214004 45.0 1.0 no 5615 chrIX_86298r 17338 no_effect YIL140W 935 - TCTTACCGAGTAATTCATCT K|318|N silent|AAG>AAA|K|318 G|317|A G|317|D AXL2 AXiaL 2 bud site selection 823.0 0 0 0 0 -0.3874730195628021 P38928 0.9355990290641784 0.9499930143356324 0.9446240067481996 0.324016273021698 0.8504738807678223 0.6276252269744873 44.329318263514146 35.0 1.0 no 5616 chrIX_86348r 17339 no_effect YIL140W 985 - ATCACCATAAGTATCATAAA D|335|H D|335|N G|334|A G|334|D AXL2 AXiaL 2 bud site selection 823.0 0 0 0 0 0.7679231003081005 P38928 0.9486550092697144 0.956179976463318 0.9499930143356324 0.9446240067481996 0.0 0.0 0.4371764361858368 0.3950151801109314 36.170121122685366 25.0 1.0 no 5617 chrIX_86531 17343 no_effect YIL140W 1165 + ATTCAAGCCAAGACCATGAC S|390|* S|390|L AXL2 AXiaL 2 bud site selection 823.0 0 1 0 0 0.10574858763416073 P38928 0.9298099875450134 0.05484320595860481 46.04365791676753 45.0 1.0 no 5618 chrIX_86656 17346 no_effect YIL140W 1290 + GAGCTATATTTTAACATCAT L|432|V silent|CTA>TTA|L|432 AXL2 AXiaL 2 bud site selection 823.0 0 0 0 0 0.7015322685490089 P38928 0.9512209892272948 0.0 37.53444617389221 25.0 1.0 no 5619 chrIX_86983 17351 no_effect YIL140W 1617 + AACTTACCGCATGCTATTAG N|540|K silent|AAC>AAT|N|540 P|542|A P|542|S AXL2 AXiaL 2 bud site selection 823.0 0 0 0 0 -0.16991276474196773 P38928 0.9439849853515624 0.9562489986419678 0.9498909711837769 0.4253434538841248 0.7263661623001099 0.7803654074668884 44.82559899305403 40.0 1.0 no 5620 chrIX_87022r 17353 no_effect YIL140W 1659 - TCTTGATTTGGTTTATTTGC E|560|Q E|560|K AXL2 AXiaL 2 bud site selection 823.0 0 0 0 0 0.6717866645861024 P38928 0.956179976463318 0.9475290179252625 0.6681562066078186 0.8944218158721924 42.95696261287464 30.0 1.0 no 5621 chrIX_87099 17355 no_effect YIL140W 1733 + TACTTCAATAGCAAGAAGAT T|579|S T|579|I S|580|* S|580|L AXL2 AXiaL 2 bud site selection 823.0 0 0 0 0 -1.041441097179116 P38928 0.9491789937019348 0.9472420215606691 0.9298099875450134 0.8940064907073975 0.18289445340633392 0.031128812581300732 36.18465056845997 30.0 1.0 no 5622 chrIX_87176r 17357 no_effect YIL140W 1813 - ATCTCTCTTTTCATCCACGC D|611|H D|611|N R|610|T R|610|K AXL2 AXiaL 2 bud site selection 823.0 0 1 0 0 0.4975290130798158 P38928 0.9486550092697144 0.956179976463318 0.932735025882721 0.955805003643036 0.11908697336912155 0.5801421403884888 0.5513461232185364 1.0 52.51423059834815 45.0 1.0 no 5623 chrIX_108371r 17364 essential YIL129C 4844 + CCAAAATATACACGTATCGC Q|1616|E Q|1616|* TAO3 Transcriptional Activator of OCH1 2376.0 0 0 0 0 0.3711438334161393 P40468 0.9590039849281312 1.0 40.542568762546466 40.0 0.0 no 5624 chrIX_108719r 17368 essential YIL129C 4496 + TTCTTATACCAAGGTATTTA S|1500|C S|1500|F TAO3 Transcriptional Activator of OCH1 2376.0 0 0 0 0 0.4122686641618348 P40468 0.945252001285553 0.9294660091400146 0.02685183472931385 0.025980187579989437 39.834869860127704 25.0 0.0 no 5625 chrIX_108728r 17369 essential YIL129C 4487 + ACATAATTCTTCTTATACCA H|1497|D H|1497|Y TAO3 Transcriptional Activator of OCH1 2376.0 0 0 0 0 0.5260298802780926 P40468 0.9473130106925964 0.9489949941635132 0.117733396589756 1.0 39.800303018637074 25.0 0.0 no 5626 chrIX_108813 17370 essential YIL129C 4405 - CACTAAACCATACAAACCCA V|1475|L V|1475|M TAO3 Transcriptional Activator of OCH1 2376.0 0 0 0 0 -0.4676668193285955 P40468 0.9539830088615416 0.9587630033493042 0.04919983074069023 0.022605618461966515 42.73412336832706 40.0 0.0 no 5627 chrIX_108917r 17372 essential YIL129C 4298 + TTCACACCACTCACATCCTT S|1434|* S|1434|L H|1435|D H|1435|Y TAO3 Transcriptional Activator of OCH1 2376.0 0 0 0 0 -0.4727705385254866 P40468 0.9298099875450134 0.9473130106925964 0.9489949941635132 0.7234277129173279 0.3549239039421081 1.0 52.37808996201853 45.0 0.0 no 5628 chrIX_109203 17374 essential YIL129C 4015 - TTCTATTCCAGTTGTAATAG E|1345|Q E|1345|K TAO3 Transcriptional Activator of OCH1 2376.0 0 0 0 0 0.794756168341572 P40468 0.956179976463318 0.9475290179252625 0.0 0.0 40.72315189857608 30.0 0.0 no 5629 chrIX_109264 17375 essential YIL129C 3954 - GCATATCTTTCTTCAGATAT A|1325|P A|1325|T R|1323|T R|1323|K TAO3 Transcriptional Activator of OCH1 2376.0 0 0 0 0 -0.6561643784881068 P40468 0.9573720097541808 0.9523990154266356 0.932735025882721 0.955805003643036 0.27670520544052124 0.5681901574134827 0.0 0.0 42.903575521722644 30.0 0.0 no 5630 chrIX_109388r 17376 essential YIL129C 3827 + TCTTATATTGAGCTACTATA L|1277|V L|1277|F TAO3 Transcriptional Activator of OCH1 2376.0 0 0 0 0 0.08102595522363784 P40468 0.9512209892272948 0.9587849974632264 0.3217609226703644 0.4374311864376068 38.48163005567904 25.0 0.0 no 5631 chrIX_109815 17382 essential YIL129C 3403 - CCTGCCATGCTGAGGAATAT R|1141|T R|1141|K G|1140|A G|1140|D TAO3 Transcriptional Activator of OCH1 2376.0 0 1 0 0 -1.269101673236297 P40468 0.932735025882721 0.955805003643036 0.9499930143356324 0.9446240067481996 0.010905313305556774 0.23004138469696045 0.4444192051887512 0.03350144252181053 51.60780839342437 50.0 0.0 no 5632 chrIX_109706r 17384 essential YIL129C 3509 + TGCAAAGTATATTATGATTA A|1171|G A|1171|V TAO3 Transcriptional Activator of OCH1 2376.0 0 0 0 0 0.09848169894559064 P40468 0.9484469890594482 0.9504740238189696 0.35167351365089417 0.2551566362380981 33.44191920853149 20.0 0.0 no 5633 chrIX_110485 17395 essential YIL129C 2733 - TCCTCTTGTTCTGCATCGAT E|917|D silent|GAG>GAA|E|917 E|918|Q E|918|K TAO3 Transcriptional Activator of OCH1 2376.0 0 0 0 0 0.2830536574120657 P40468 0.94931298494339 0.956179976463318 0.9475290179252625 0.5966055393218994 0.14640985429286954 0.4045699536800385 53.22725352577442 45.0 0.0 no 5634 chrIX_111227r 17403 essential YIL129C 1988 + ATCTTTCAATGGCTCTAACC S|664|C S|664|F F|665|L silent|TTC>TTT|F|665 TAO3 Transcriptional Activator of OCH1 2376.0 0 0 0 0 0.4397424371428106 P40468 0.945252001285553 0.9294660091400146 0.9387490153312684 0.025984007865190503 0.01788957603275776 0.05149439349770546 46.2012694636079 40.0 0.0 no 5635 chrIX_111414r 17405 essential YIL129C 1801 + AAACTTTAAATAATACTACA T|602|S T|602|I TAO3 Transcriptional Activator of OCH1 2376.0 0 0 0 0 0.32013114197644604 P40468 0.9491789937019348 0.9472420215606691 0.5736361145973206 0.008936796337366104 28.11602211878437 15.0 0.0 no 5636 chrIX_111492 17406 essential YIL129C 1726 - AATCCTTTCATTCAGACTTT R|581|S silent|AGG>AGA|R|581 R|581|T R|581|K TAO3 Transcriptional Activator of OCH1 2376.0 0 0 0 0 1.7449052852592153 P40468 0.9087679982185364 0.932735025882721 0.955805003643036 0.011628100648522377 0.014731827192008497 1.0 43.752688723019155 30.0 0.0 no 5637 chrIX_111670 17412 essential YIL129C 1548 - GACATTGCCTCTACCCACGT M|522|I M|522|I TAO3 Transcriptional Activator of OCH1 2376.0 0 0 0 0 0.226985406232035 P40468 0.9553959965705872 0.9553959965705872 1.0 1.0 57.055248661022695 55.00000000000001 0.0 no 5638 chrIX_112145 17422 essential YIL129C 1073 - TTTCATTTAGCACCCTGCAT E|364|Q E|364|K TAO3 Transcriptional Activator of OCH1 2376.0 0 0 0 0 0.11110299452024362 P40468 0.956179976463318 0.9475290179252625 0.022247852757573128 0.017425695434212685 51.965305329125606 40.0 0.0 no 5639 chrIX_112245 17425 essential YIL129C 973 - TTTCAATTGTGAGTTCGCTA L|330|F silent|TTG>TTA|L|330 TAO3 Transcriptional Activator of OCH1 2376.0 0 0 0 0 0.07919477608791292 P40468 0.9587849974632264 0.15393859148025513 44.47741165563548 35.0 0.0 no 5640 chrIX_112294 17426 essential YIL129C 924 - CTGCTACTAGCTTTGATTAA S|314|T S|314|N S|313|T S|313|N TAO3 Transcriptional Activator of OCH1 2376.0 0 1 0 0 0.3709594538075642 P40468 0.9512869715690612 0.9536849856376648 0.9512869715690612 0.9536849856376648 43.0880771910393 35.0 0.0 no 5641 chrIX_112317 17427 essential YIL129C 901 - AACTTTGTTGTTGAAAGATG V|307|L V|307|I TAO3 Transcriptional Activator of OCH1 2376.0 0 1 0 0 0.34823987296028897 P40468 0.9539830088615416 0.9574310183525084 0.31558385491371155 0.20008957386016848 35.69051181388915 30.0 0.0 no 5642 chrIX_112546 17430 essential YIL129C 672 - AACATCATTGCATCAATCAC M|230|I M|230|I M|229|I M|229|I TAO3 Transcriptional Activator of OCH1 2376.0 0 0 0 0 0.2499467462001204 P40468 0.9553959965705872 0.9553959965705872 0.9553959965705872 0.9553959965705872 0.0 0.0 0.08839154988527298 0.08839154988527298 40.57267594418363 35.0 0.0 no 5643 chrIX_112636 17431 essential YIL129C 582 - TCACCAAGAATTTCTACAAT G|200|A G|200|D E|201|Q E|201|K TAO3 Transcriptional Activator of OCH1 2376.0 0 0 0 0 0.8189073893766081 P40468 0.9499930143356324 0.9446240067481996 0.956179976463318 0.9475290179252625 1.0 0.07482575625181198 0.0 0.0 38.69722284154591 30.0 0.0 no 5644 chrIX_112638 17432 essential YIL129C 580 - ACCAAGAATTTCTACAATTG G|200|R G|200|S G|200|A G|200|D TAO3 Transcriptional Activator of OCH1 2376.0 0 0 0 0 0.7333498056567371 P40468 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0574059784412384 0.6157656908035278 1.0 0.07482575625181198 36.8565259273168 30.0 0.0 no 5645 chrIX_112639 17433 essential YIL129C 579 - CCAAGAATTTCTACAATTGG G|200|R G|200|S TAO3 Transcriptional Activator of OCH1 2376.0 0 0 0 0 0.4639657806791328 P40468 0.941340982913971 0.951104998588562 0.0574059784412384 0.6157656908035278 38.694982216341494 35.0 0.0 no 5646 chrIX_112852 17440 essential YIL129C 366 - ATTCTTTGCTGCTTTTGTTC R|128|T R|128|K TAO3 Transcriptional Activator of OCH1 2376.0 0 0 0 0 0.2245521791088595 P40468 0.932735025882721 0.955805003643036 0.5212175846099854 0.8930862545967102 48.6708430757954 35.0 0.0 no 5647 chrIX_112910r 17442 essential YIL129C 305 + TCTTCCGCCTACCTTTGTTG L|103|V L|103|F P|104|A P|104|S TAO3 Transcriptional Activator of OCH1 2376.0 0 0 0 0 0.31838742897334504 P40468 0.9512209892272948 0.9587849974632264 0.9562489986419678 0.9498909711837769 1.0 0.18559569120407104 0.7438991665840149 0.7337521314620972 56.36380232394521 50.0 0.0 no 5648 chrIX_112999r 17448 essential YIL129C 216 + TCTCCTACTGATATGTCTGA P|74|A P|74|S S|73|C S|73|F TAO3 Transcriptional Activator of OCH1 2376.0 0 0 0 0 0.5503403766690921 P40468 0.9562489986419678 0.9498909711837769 0.945252001285553 0.9294660091400146 0.5895622372627258 0.16434302926063538 0.07585354894399643 0.1166464239358902 47.73928812232322 40.0 0.0 no 5649 chrIX_113045r 17451 essential YIL129C 170 + TCCTCTTCACCAATCCGTTA P|58|R P|58|L P|58|A P|58|S TAO3 Transcriptional Activator of OCH1 2376.0 0 0 0 0 -0.8694554262033835 P40468 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.4292091429233551 0.2434345483779907 0.5562276244163513 0.4753017425537109 53.358179730570036 45.0 0.0 no 5650 chrIX_113113r 17455 essential YIL129C 102 + TCAATAGATATTGATCCTTC S|35|* S|35|L TAO3 Transcriptional Activator of OCH1 2376.0 0 0 0 0 0.06745590282136542 P40468 0.9298099875450134 39.40969034900479 30.0 0.0 no 5651 chrIX_113159 17457 essential YIL129C 59 - CTTCTGCTTTATTTGTCGGT E|26|Q E|26|K A|25|P A|25|T TAO3 Transcriptional Activator of OCH1 2376.0 0 0 0 0 0.01996133882112161 P40468 0.956179976463318 0.9475290179252625 0.9573720097541808 0.9523990154266356 50.026490528544166 40.0 0.0 no 5652 chrIX_113158 17458 essential YIL129C 60 - CCTTCTGCTTTATTTGTCGG G|27|R G|27|S E|26|Q E|26|K TAO3 Transcriptional Activator of OCH1 2376.0 0 0 0 0 0.002862117947093901 P40468 0.941340982913971 0.951104998588562 0.956179976463318 0.9475290179252625 51.16045624118527 45.0 0.0 no 5653 chrIX_118158 17469 essential YIL126W 166 + AGCAGCTACTCTACCGCTAT Q|57|E Q|57|* L|58|V silent|CTA>TTA|L|58 STH1 SNF Two Homolog 1359.0 0 1 0 0 0.5610585285081298 P32597 0.9590039849281312 0.9512209892272948 54.28586734378354 50.0 1.0 no 5654 chrIX_118159 17470 essential YIL126W 167 + GCAGCTACTCTACCGCTATA Q|57|E Q|57|* L|58|V silent|CTA>TTA|L|58 STH1 SNF Two Homolog 1359.0 0 1 0 0 0.2422299525608339 P32597 0.9590039849281312 0.9512209892272948 53.603108169284894 50.0 1.0 no 5655 chrIX_118196r 17471 essential YIL126W 207 - ATCTCCAACTTGTTTTCCTT E|75|D silent|GAG>GAA|E|75 E|75|Q E|75|K STH1 SNF Two Homolog 1359.0 0 0 0 0 -1.3288625113566512 P32597 0.94931298494339 0.956179976463318 0.9475290179252625 49.51901675796864 35.0 1.0 no 5656 chrIX_118192r 17472 essential YIL126W 203 - CCAACTTGTTTTCCTTTGGA L|74|F silent|TTG>TTA|L|74 K|73|N silent|AAG>AAA|K|73 STH1 SNF Two Homolog 1359.0 0 0 0 0 0.13696740774260618 P32597 0.9587849974632264 0.9355990290641784 49.408876372205725 40.0 1.0 no 5657 chrIX_118353r 17474 essential YIL126W 364 - ATCTTTCTCCAGTAACTGTA D|128|H D|128|N E|126|D silent|GAG>GAA|E|126 STH1 SNF Two Homolog 1359.0 0 0 0 0 -1.574731253436048 P32597 0.9486550092697144 0.956179976463318 0.94931298494339 46.34980848234051 35.0 1.0 no 5658 chrIX_118474 17475 essential YIL126W 482 + ATCAGCAGATTTCAATGCGA S|162|* S|162|L A|163|G A|163|V STH1 SNF Two Homolog 1359.0 0 1 0 0 0.1721188225260183 P32597 0.9298099875450134 0.9484469890594482 0.9504740238189696 0.34221261739730835 0.4614965915679932 0.4469215571880341 45.1782104203765 40.0 1.0 no 5659 chrIX_118743 17479 essential YIL126W 751 + TAACTAAACAAAAATCGATT T|252|S T|252|I STH1 SNF Two Homolog 1359.0 0 0 0 0 -1.227379168271015 P32597 0.9491789937019348 0.9472420215606691 0.8515136241912842 0.14565779268741608 28.403796579417644 20.0 1.0 no 5660 chrIX_118879 17483 essential YIL126W 887 + TGTCCCACAAACCGTTCGTT silent|GTC>GTG|V|297 silent|GTC>GTT|V|297 P|298|A P|298|S STH1 SNF Two Homolog 1359.0 0 0 0 0 1.1439835874707165 P32597 0.9562489986419678 0.9498909711837769 0.5311889052391052 0.19137461483478546 52.94592517831518 50.0 1.0 no 5661 chrIX_118883r 17485 essential YIL126W 894 - TCTGCCAAACGAACGGTTTG E|305|Q E|305|K A|304|P A|304|T STH1 SNF Two Homolog 1359.0 0 0 0 0 -2.383531003407361 P32597 0.956179976463318 0.9475290179252625 0.9573720097541808 0.9523990154266356 0.21842020750045776 0.3336580991744995 0.02869858033955097 1.0 46.07017760635183 50.0 1.0 yes 5662 chrIX_119128 17486 essential YIL126W 1136 + TGCTTTGAAGTCTAACGATG A|380|G A|380|V STH1 SNF Two Homolog 1359.0 0 0 0 0 0.3737474870917208 P32597 0.9484469890594482 0.9504740238189696 0.0 0.0 41.2088181704288 40.0 1.0 no 5663 chrIX_119056 17487 essential YIL126W 1064 + CGCTTCATTACACAATCAAA A|356|G A|356|V S|357|* S|357|L STH1 SNF Two Homolog 1359.0 0 0 0 0 0.3102087654770653 P32597 0.9484469890594482 0.9504740238189696 0.9298099875450134 0.34597671031951904 0.514171302318573 0.20639175176620486 39.875227818107994 35.0 1.0 no 5664 chrIX_119297r 17491 essential YIL126W 1308 - TCTCTTTCTTCATCTGTAAT R|442|T R|442|K E|443|Q E|443|K STH1 SNF Two Homolog 1359.0 0 0 0 0 -0.27109794026632794 P32597 0.932735025882721 0.955805003643036 0.956179976463318 0.9475290179252625 0.6173821687698364 0.9653267860412598 0.2498300969600677 0.5048062205314636 43.88832299704813 30.0 1.0 no 5665 chrIX_119369 17492 essential YIL126W 1377 + AAACAACCTTCTATTCTTGT Q|461|E Q|461|* P|462|A P|462|S STH1 SNF Two Homolog 1359.0 0 1 0 0 0.379363189091496 P32597 0.9590039849281312 0.9562489986419678 0.9498909711837769 0.0 0.29505985975265503 0.1097244918346405 40.97429967841464 30.0 1.0 no 5666 chrIX_119372 17493 essential YIL126W 1380 + CAACCTTCTATTCTTGTTGG P|462|A P|462|S P|462|R P|462|L STH1 SNF Two Homolog 1359.0 0 1 0 0 -0.3917615193925239 P32597 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.29505985975265503 0.1097244918346405 0.0048054782673716545 0.006467819679528475 46.1579125859165 40.0 1.0 no 5667 chrIX_119664 17497 essential YIL126W 1672 + ACTCTTTACAGCATCAAATA S|559|C S|559|F H|558|Q silent|CAC>CAT|H|558 STH1 SNF Two Homolog 1359.0 0 0 0 0 -1.313651601592804 P32597 0.945252001285553 0.9294660091400146 0.9588389992713928 0.050751961767673485 0.04871492087841034 0.031636055558919914 39.762993746600216 30.0 1.0 no 5668 chrIX_119743 17500 essential YIL126W 1751 + TCTTTTATCAAAACATGATT L|585|V L|585|F STH1 SNF Two Homolog 1359.0 0 0 0 0 -0.8514813977625981 P32597 0.9512209892272948 0.9587849974632264 0.31047120690345764 0.015069724060595037 33.669766751419786 20.0 1.0 no 5669 chrIX_119884 17502 essential YIL126W 1892 + GAACAATCTACCAGAATTAT N|632|K silent|AAC>AAT|N|632 STH1 SNF Two Homolog 1359.0 0 0 0 0 0.022805701954291324 P32597 0.9439849853515624 0.0 36.98322213771843 30.0 1.0 no 5670 chrIX_119894r 17503 essential YIL126W 1905 - TTCAACAGTGCCCATAATTC L|641|F silent|TTG>TTA|L|641 silent|CTG>CTC|L|640 silent|CTG>CTA|L|640 STH1 SNF Two Homolog 1359.0 0 0 0 0 -1.5270008935365382 P32597 0.9587849974632264 0.0 46.3714978254755 40.0 1.0 no 5671 chrIX_119988r 17505 essential YIL126W 1999 - TTCTAGTTTCTCTTGGGTAC E|673|Q E|673|K STH1 SNF Two Homolog 1359.0 0 1 0 0 -0.9343419026929658 P32597 0.956179976463318 0.9475290179252625 0.032162558287382126 0.025590911507606503 48.40377921387528 40.0 1.0 no 5672 chrIX_119293r 17507 essential YIL126W 1304 - TTTCTTCATCTGTAATTGGT E|441|Q E|441|K E|440|Q E|440|K STH1 SNF Two Homolog 1359.0 0 0 0 0 0.10717455145245952 P32597 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.4681130647659302 0.9310837984085084 0.1626451015472412 0.05753324925899505 43.439367766191985 30.0 1.0 no 5673 chrIX_120188 17509 essential YIL126W 2196 + AACGCGCTATTTGTTGGTGC N|733|K silent|AAC>AAT|N|733 A|734|G A|734|V STH1 SNF Two Homolog 1359.0 0 0 0 0 -0.3627863997298474 P32597 0.9439849853515624 0.9484469890594482 0.9504740238189696 0.5351682305335999 0.18803170323371887 0.1696816086769104 50.81752366484715 50.0 1.0 no 5674 chrIX_120283r 17514 essential YIL126W 2294 - CTTCATCAAATACGAATGGA E|771|Q E|771|K D|770|H D|770|N STH1 SNF Two Homolog 1359.0 0 0 0 0 -3.002157966819247 P32597 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.02373290061950684 0.021059749647974968 0.010568995028734207 0.02698901481926441 37.902765606862545 35.0 1.0 yes 5675 chrIX_120287r 17515 essential YIL126W 2298 - TCCACTTCATCAAATACGAA silent|GTG>GTC|V|772 silent|GTG>GTA|V|772 E|773|Q E|773|K STH1 SNF Two Homolog 1359.0 0 0 0 0 -0.4744911136128147 P32597 0.956179976463318 0.9475290179252625 0.0 0.0 40.62562931298823 35.0 1.0 no 5676 chrIX_120389 17519 essential YIL126W 2397 + CTACCGAAATTCAAAGCCTC P|801|A P|801|S P|801|R P|801|L STH1 SNF Two Homolog 1359.0 0 0 0 0 -0.02004770001244352 P32597 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.02000758796930313 0.018115488812327385 0.0063884537667036065 0.004895334132015705 44.10450639253639 45.0 1.0 no 5677 chrIX_120430 17520 essential YIL126W 2438 + TTTCCAAATGACTCAAGTTA F|814|L silent|TTC>TTT|F|814 Q|815|E Q|815|* STH1 SNF Two Homolog 1359.0 0 0 0 0 -1.5776680628472002 P32597 0.9387490153312684 0.9590039849281312 0.0 0.0 39.53776839847063 30.0 1.0 no 5678 chrIX_120433r 17521 essential YIL126W 2444 - TATCCATAACTTGAGTCATT D|821|H D|821|N M|820|I M|820|I STH1 SNF Two Homolog 1359.0 0 0 0 0 0.3801086394649062 P32597 0.9486550092697144 0.956179976463318 0.9553959965705872 0.9553959965705872 0.007275761105120181 0.21126589179039 0.0 0.0 41.55471251951997 30.0 1.0 no 5679 chrIX_120469r 17523 essential YIL126W 2480 - ACTTCAAATCTTTCATTCTT K|833|N silent|AAG>AAA|K|833 L|832|F silent|TTG>TTA|L|832 STH1 SNF Two Homolog 1359.0 0 0 0 0 0.4375955037830047 P32597 0.9355990290641784 0.9587849974632264 0.026957467198371887 0.14344540238380432 39.80250935245897 25.0 1.0 no 5680 chrIX_120667r 17526 essential YIL126W 2678 - TATCTTGGGCCTGTAAATCT D|899|H D|899|N STH1 SNF Two Homolog 1359.0 0 0 0 0 -1.7939693578195293 P32597 0.9486550092697144 0.956179976463318 0.0 0.0 47.564574016878396 40.0 1.0 no 5681 chrIX_139876r 17535 essential YIL118W 127 - AACAGTAGGCTCATAAACTT V|49|L V|49|I RHO3 Ras HOmolog 231.0 0 0 0 0 -0.19563134771625235 Q00245 0.9539830088615416 0.9574310183525084 0.009618867188692093 0.19861340522766116 -0.00279999990016222 -0.11906000226736067 40.69450467596738 35.0 1.0 no 5682 chrIX_139936 17536 essential YIL118W 184 + AACATATCACGCTATCGTTG H|63|D H|63|Y RHO3 Ras HOmolog 231.0 0 0 0 0 0.13536091166317515 Q00245 0.9473130106925964 0.9489949941635132 0.4439896047115326 0.3658638894557953 0.051419999450445175 -0.6974599957466125 42.881482984025524 40.0 1.0 no 5683 chrIX_140229 17539 essential YIL118W 477 + AACATAAATAGCACCTCAAA N|160|K silent|AAC>AAT|N|160 RHO3 Ras HOmolog 231.0 0 1 0 0 0.2025244517286706 Q00245 0.9439849853515624 0.9140688180923462 36.66717880448885 30.0 1.0 no 5684 chrIX_158093 17541 essential YIL109C 2053 - CACTATTTCCTTCTTGTACG V|691|L V|691|M SEC24 SECretory 926.0 0 1 0 0 0.674316265017415 P40482 0.9539830088615416 0.9587630033493042 0.18939825892448425 0.033317241817712784 0.036600001156330116 -0.09120000153779984 46.395921749563904 40.0 0.0 no 5685 chrIX_158101r 17542 essential YIL109C 2042 + TATCTTAGCCACGTACAAGA I|682|M silent|ATC>ATT|I|682 SEC24 SECretory 926.0 0 1 0 0 0.2197173756933697 P40482 0.9598389863967896 0.07483723759651184 0.13920000195503235 45.19488848568977 40.0 0.0 no 5686 chrIX_158244 17547 essential YIL109C 1902 - TCTGCCAACGATTCCGTGGT E|641|Q E|641|K A|640|P A|640|T SEC24 SECretory 926.0 0 0 0 0 -0.7614867379662698 P40482 0.956179976463318 0.9475290179252625 0.9573720097541808 0.9523990154266356 0.19435256719589236 0.047006618231534965 0.07453489303588867 0.4030709862709045 0.2150000035762787 -0.11339999735355374 -1.0795999765396118 0.1793999969959259 55.25773029161565 55.00000000000001 0.0 no 5687 chrIX_158465 17551 essential YIL109C 1681 - TCTCAAACCTGTGGAACCAC L|566|F silent|TTG>TTA|L|566 R|567|T R|567|K SEC24 SECretory 926.0 0 0 0 0 -2.3427659662883555 P40482 0.9587849974632264 0.932735025882721 0.955805003643036 0.11525210738182068 0.006350296083837748 0.1315784901380539 6.627999782562256 0.6955999732017517 0.44859999418258667 47.83945226963061 50.0 0.0 yes 5688 chrIX_158583r 17552 essential YIL109C 1560 + GGTCAAACGCATTTCTATCC Q|522|E Q|522|* SEC24 SECretory 926.0 0 0 0 0 1.1456539519313853 P40482 0.9590039849281312 0.022293085232377045 0.00019999999494757506 47.55130780839772 45.0 0.0 no 5689 chrIX_158802r 17554 essential YIL109C 1341 + ACTTTGCCCAACTTAGGCAT T|448|S T|448|I P|450|A P|450|S SEC24 SECretory 926.0 0 0 0 0 0.8952724717761673 P40482 0.9491789937019348 0.9472420215606691 0.9562489986419678 0.9498909711837769 1.0 0.005527900531888008 0.0 0.0 1.215999960899353 2.4749999046325684 2.778599977493286 3.708600044250488 52.295405041083434 45.0 0.0 no 5690 chrIX_158808r 17555 essential YIL109C 1335 + TCAGGTACTTTGCCCAACTT S|446|* S|446|L SEC24 SECretory 926.0 0 0 0 0 -0.375343454642421 P40482 0.9298099875450134 0.03878482058644295 -0.9538000226020812 52.3872905574774 45.0 0.0 no 5691 chrIX_159066 17562 essential YIL109C 1080 - TCATTGTTTTCAGAATCCAA E|367|Q E|367|K SEC24 SECretory 926.0 0 0 0 0 0.9191452939465126 P40482 0.956179976463318 0.9475290179252625 0.4560531079769135 0.7062550783157349 41.7348574298793 30.0 0.0 no 5692 chrIX_159082r 17563 essential YIL109C 1061 + TCACTACTTTAAAATCCCAT H|355|Q silent|CAC>CAT|H|355 H|355|D H|355|Y SEC24 SECretory 926.0 0 0 0 0 0.4340135383165435 P40482 0.9588389992713928 0.9473130106925964 0.9489949941635132 0.007475901860743761 0.0152281504124403 0.15353761613368988 1.503000020980835 3.9493999481201167 -1.2200000286102295 41.133028225830905 30.0 0.0 no 5693 chrIX_159140 17565 essential YIL109C 1006 - TCTTTCATCATGGTTTGGAA R|342|T R|342|K E|341|Q E|341|K SEC24 SECretory 926.0 0 0 0 0 -5.390582593169483 P40482 0.932735025882721 0.955805003643036 0.956179976463318 0.9475290179252625 0.08876410871744156 0.04743264988064766 0.5457022786140442 0.9308770298957824 3.261199951171875 1.1269999742507937 -0.37619999051094055 -0.5085999965667725 44.65573855708294 35.0 0.0 yes 5694 chrIX_159269 17571 essential YIL109C 877 - TCTTAGAGTATATTCCTTTG R|299|T R|299|K SEC24 SECretory 926.0 0 0 0 0 0.07802996258258668 P40482 0.932735025882721 0.955805003643036 0.0 0.0 1.0155999660491943 0.41760000586509705 41.70089031188911 30.0 0.0 no 5695 chrIX_159324 17572 essential YIL109C 822 - TTTCTGTCGTATCTACTCTT R|280|T R|280|K SEC24 SECretory 926.0 0 1 0 0 -0.5349496034477188 P40482 0.932735025882721 0.955805003643036 0.014735399745404719 0.07475711405277252 3.861000061035156 1.827399969100952 47.04488764827136 35.0 0.0 no 5696 chrIX_159633 17581 essential YIL109C 513 - GACGCATTGGACAATTCAGA silent|GCG>GCC|A|177 silent|GCG>GCA|A|177 A|177|P A|177|T SEC24 SECretory 926.0 0 0 0 1 0.7512611775930713 P40482 0.9573720097541808 0.9523990154266356 0.2067689299583435 0.2669129967689514 5.186999797821045 3.388200044631958 44.97784434990415 45.0 0.0 no 5697 chrIX_159781r 17588 essential YIL109C 362 + TGGCCAACCTAGCGCCGCAA silent|GGC>GGG|G|122 silent|GGC>GGT|G|122 Q|123|E Q|123|* SEC24 SECretory 926.0 0 0 0 0 0.7405979064802198 P40482 0.9590039849281312 1.0 59.32773542555145 65.0 0.0 no 5698 chrIX_159817r 17592 essential YIL109C 326 + GCAGCAACAGCAACAACCAA Q|110|E Q|110|* Q|111|E Q|111|* SEC24 SECretory 926.0 0 0 0 0 -0.02225582577002455 P40482 0.9590039849281312 0.9590039849281312 0.4855335652828217 1.0 47.01035787560068 50.0 0.0 no 5699 chrIX_159865r 17596 essential YIL109C 278 + TAACGCTTATATGCAGCCAC N|94|K silent|AAC>AAT|N|94 A|95|G A|95|V SEC24 SECretory 926.0 0 0 0 0 -0.2402859144888603 P40482 0.9439849853515624 0.9484469890594482 0.9504740238189696 0.934787094593048 0.4049579799175263 0.2673014998435974 47.56322656171966 45.0 0.0 no 5700 chrIX_160050r 17604 essential YIL109C 93 + CCGCAGGATCCTGCTGCAGC Q|33|E Q|33|* P|32|R P|32|L SEC24 SECretory 926.0 0 0 0 0 -0.7711340029484416 P40482 0.9590039849281312 0.9432820081710817 0.9430609941482544 1.0 0.37894171476364136 0.6627687215805054 63.326174591502244 70.0 0.0 no 5701 chrIX_160116r 17609 essential YIL109C 27 + CCACAAGCTCAGCTCCAGTA Q|11|E Q|11|* P|10|R P|10|L SEC24 SECretory 926.0 0 0 0 0 -1.8721492164143425 P40482 0.9590039849281312 0.9432820081710817 0.9430609941482544 1.0 0.05614892765879631 0.07473171502351761 56.374163239543755 55.00000000000001 0.0 no 5702 chrIX_160116 17610 essential YIL109C 30 - CCATACTGGAGCTGAGCTTG G|17|R G|17|R Q|15|H silent|CAG>CAA|Q|15 SEC24 SECretory 926.0 0 0 0 0 0.7603613229443256 P40482 0.941340982913971 0.941340982913971 0.9570760130882264 0.3837134540081024 0.3837134540081024 0.1681743562221527 52.298999216697375 55.00000000000001 0.0 no 5703 chrIX_166535r 17611 essential YIL106W 38 - CTCTAGTAGATCTTATTGTT R|19|T R|19|K MOB1 Mps One Binder 314.0 0 1 0 0 -0.14157142463138367 P40484 0.932735025882721 0.955805003643036 41.84896627894518 30.0 1.0 no 5704 chrIX_166660r 17615 essential YIL106W 163 - TGCTCTATTGTTAATAGTAT A|61|P A|61|T R|60|T R|60|K MOB1 Mps One Binder 314.0 0 1 0 0 -0.8231175222394361 P40484 0.9573720097541808 0.9523990154266356 0.932735025882721 0.955805003643036 39.06038575073711 25.0 1.0 no 5705 chrIX_166741 17618 essential YIL106W 241 + CCGTCCTCACTACGCCAAAG silent|CCC>CCG|P|81 silent|CCC>CCT|P|81 silent|GTC>GTG|V|82 silent|GTC>GTT|V|82 MOB1 Mps One Binder 314.0 0 0 0 0 -1.066196598524222 P40484 53.86486666440078 60.0 1.0 no 5706 chrIX_166773r 17621 essential YIL106W 276 - ACATTTTGTAATTGTTCAGG V|99|L V|99|I MOB1 Mps One Binder 314.0 0 0 0 0 0.10624201252487607 P40484 0.9539830088615416 0.9574310183525084 0.5945568680763245 0.2714873254299164 -0.12380000203847885 -0.08529999852180481 -1.0751999616622925 -0.3192000091075897 39.81943726480353 30.0 1.0 no 5707 chrIX_166871 17624 essential YIL106W 371 + TCAAGACATCAAGCAAATTG Q|125|E Q|125|* D|126|E silent|GAC>GAT|D|126 MOB1 Mps One Binder 314.0 0 0 0 0 -0.6727708883376923 P40484 0.9590039849281312 0.9532920122146606 0.22000586986541748 1.0 2.2965199947357178 0.34279999136924744 -0.8330000042915344 36.589990094122136 35.0 1.0 no 5708 chrIX_166941r 17627 essential YIL106W 444 - TCATTCTCATCCTCACCACG E|155|Q E|155|K E|153|D silent|GAG>GAA|E|153 MOB1 Mps One Binder 314.0 0 0 0 0 -0.33381277745246984 P40484 0.956179976463318 0.9475290179252625 0.94931298494339 0.01461496204137802 0.00242633861489594 0.549909770488739 -0.04165999963879585 -0.8782600164413452 0.8284400105476379 53.031473752586976 50.0 1.0 no 5709 chrIX_167035 17629 essential YIL106W 535 + GCTCCCCACAAACATGCCCG S|180|C S|180|F C|179|W silent|TGC>TGT|C|179 MOB1 Mps One Binder 314.0 0 1 0 0 -1.0150871165148194 P40484 0.945252001285553 0.9294660091400146 0.9286419749259948 0.0011422729585319755 0.0005788594717159867 0.0 0.4649600088596344 2.8240199089050293 41.04433822631836 59.22025255597066 65.0 1.0 no 5710 chrIX_167038r 17630 essential YIL106W 541 - CATCCTCGGGCATGTTTGTG R|186|S silent|AGG>AGA|R|186 R|186|T R|186|K MOB1 Mps One Binder 314.0 0 1 0 0 -0.7963661922611359 P40484 0.9087679982185364 0.932735025882721 0.955805003643036 0.6925862431526184 0.5711965560913086 0.8785125017166138 0.8787000179290771 1.4181599617004397 -0.3692600131034851 54.770977182626886 55.00000000000001 1.0 no 5711 chrIX_167082 17634 essential YIL106W 582 + TATCTTTGGGCATTTCAAAA L|196|V L|196|F MOB1 Mps One Binder 314.0 0 0 0 0 -0.9011265592740259 P40484 0.9512209892272948 0.9587849974632264 0.07396579533815384 0.08832994848489761 3.1923999786376958 0.04039999842643738 3.357800006866455 2.5566000938415527 40.143775970340975 30.0 1.0 no 5712 chrIX_167129r 17635 essential YIL106W 632 - TCAAACATTCCACATACTTA L|217|F silent|TTG>TTA|L|217 C|216|S C|216|Y MOB1 Mps One Binder 314.0 0 0 0 0 1.3823319011589246 P40484 0.9587849974632264 0.9421560168266296 0.9290120005607604 0.0028211683966219425 0.39843717217445374 1.0 4.465079784393311 0.07398000359535217 -0.192440003156662 -0.0982000008225441 -0.4882000088691712 40.02787939999017 30.0 1.0 no 5713 chrIX_167130r 17636 essential YIL106W 633 - ATCAAACATTCCACATACTT L|217|F silent|TTG>TTA|L|217 C|216|S C|216|Y MOB1 Mps One Binder 314.0 0 0 0 0 0.4787002930881696 P40484 0.9587849974632264 0.9421560168266296 0.9290120005607604 0.0028211683966219425 0.39843717217445374 1.0 4.465079784393311 0.07398000359535217 -0.192440003156662 -0.0982000008225441 -0.4882000088691712 40.554361731908564 30.0 1.0 no 5714 chrIX_170391r 17641 essential YIL104C 1092 + ATCAAGATTGCAATCATTAC I|365|M silent|ATC>ATT|I|365 SHQ1 Small nucleolar RNAs of the box H/ACA family Quantitative accumulation 507.0 0 0 0 0 -0.01604456012457767 P40486 0.026629557833075523 0.12678000330924988 -0.319676011800766 37.5061053026916 30.0 0.0 no 5715 chrIX_170520r 17642 essential YIL104C 963 + ACAGAGAGTGCTTGGACCAT T|322|R T|322|I SHQ1 Small nucleolar RNAs of the box H/ACA family Quantitative accumulation 507.0 0 0 0 0 0.29047843753748354 P40486 0.04351836070418358 0.6489613056182861 -0.2488600015640259 -0.1320199966430664 -0.5719519853591919 0.015399999916553497 51.22042509879788 50.0 0.0 no 5716 chrIX_170719 17650 essential YIL104C 767 - TACTGTCTTTGTACCATTGC S|262|T S|262|N D|261|H D|261|N SHQ1 Small nucleolar RNAs of the box H/ACA family Quantitative accumulation 507.0 0 0 0 0 0.6526622539545619 P40486 0.5572288632392883 0.4808042049407959 0.15320388972759247 0.4926439225673676 0.2514800131320953 3.0817999839782715 0.33625999093055725 -0.6551200151443481 48.46850141501608 40.0 0.0 no 5717 chrIX_171002 17656 essential YIL104C 484 - TGTCTTCAATATTCCATTAT K|167|N silent|AAG>AAA|K|167 L|166|F silent|TTG>TTA|L|166 SHQ1 Small nucleolar RNAs of the box H/ACA family Quantitative accumulation 507.0 0 0 0 0 0.3306938801432949 P40486 0.500073254108429 0.5675877928733826 1.0792000293731692 -0.2853200137615204 -0.2081799954175949 41.034872771749406 25.0 0.0 no 5718 chrIX_171214r 17663 essential YIL104C 269 + GGACCTACCGACAAAGTTGT D|91|E silent|GAC>GAT|D|91 L|92|V silent|CTA>TTA|L|92 SHQ1 Small nucleolar RNAs of the box H/ACA family Quantitative accumulation 507.0 0 0 0 0 -0.19680167523384545 P40486 0.0 0.02135700546205044 -0.08243999630212784 0.516219973564148 48.88425030325664 50.0 0.0 no 5719 chrIX_171278 17665 essential YIL104C 208 - TACATTGATGCATTCATCTT V|76|L V|76|I SHQ1 Small nucleolar RNAs of the box H/ACA family Quantitative accumulation 507.0 0 0 0 0 -0.0861413555650894 P40486 0.2135864645242691 0.7042884826660156 0.4107800126075745 0.9711599946022034 42.402580781796864 30.0 0.0 no 5720 chrIX_171348 17669 essential YIL104C 138 - AATCTTAATCTTAAATAGTA R|52|T R|52|K SHQ1 Small nucleolar RNAs of the box H/ACA family Quantitative accumulation 507.0 0 0 0 0 0.8064924724157005 P40486 0.009631607681512831 0.05655986070632935 1.1050599813461304 -0.15967999398708346 29.976483917938648 15.0 0.0 no 5721 chrIX_191647 17675 essential YIL091C 1529 - TCCATCTTCCTGCCATGTTA W|516|S W|516|* W|516|C W|516|* UTP25 U Three Protein 721.0 0 0 0 0 -1.8830797755898256 P40498 0.3645476996898651 0.16249705851078033 56.36037867612653 45.0 0.0 no 5722 chrIX_191695r 17678 essential YIL091C 1478 + CACAAAATACATCTCGCCAG T|494|R T|494|I UTP25 U Three Protein 721.0 0 0 0 0 -0.2009448976585756 P40498 0.040547676384449005 0.04778241366147995 42.99128077236463 45.0 0.0 no 5723 chrIX_191879 17682 essential YIL091C 1297 - AATCACCATCAACTCTATTG silent|GTG>GTC|V|438 silent|GTG>GTA|V|438 V|438|L V|438|M UTP25 U Three Protein 721.0 0 0 0 0 0.3013148050358665 P40498 0.23560963571071625 0.01657051220536232 41.241864448854024 35.0 0.0 no 5724 chrIX_192064r 17686 essential YIL091C 1109 + ATCTTTCCAACACATATTTA S|371|C S|371|F F|372|L silent|TTC>TTT|F|372 UTP25 U Three Protein 721.0 0 0 0 0 0.7300406223192859 P40498 0.0038875578902661796 0.0032143199350684877 0.0 40.13767864577 25.0 0.0 no 5725 chrIX_192249r 17689 essential YIL091C 924 + GACACTGAACACCTAGATCA D|309|E silent|GAC>GAT|D|309 T|310|S T|310|I UTP25 U Three Protein 721.0 0 0 0 0 0.0038497024511215954 P40498 0.9948588013648988 0.301481693983078 0.5773757696151733 45.011597155110614 45.0 0.0 no 5726 chrIX_192365 17691 essential YIL091C 811 - CTCGTCTTCGTCCTTTTCGT E|277|Q E|277|K D|276|H D|276|N UTP25 U Three Protein 721.0 0 0 0 0 -0.7183345378014444 P40498 0.6036467552185059 0.8812476992607117 0.07976175844669342 0.31235769391059875 56.019446234049504 50.0 0.0 no 5727 chrIX_192558 17693 essential YIL091C 618 - GCTTCCTCACCAATTACTAC A|213|P A|213|T E|212|Q E|212|K UTP25 U Three Protein 721.0 0 0 0 0 1.5810059360607107 P40498 0.2799573838710785 0.5820602178573608 0.5417353510856628 0.7789769768714905 49.81870553265161 45.0 0.0 no 5728 chrIX_192605 17694 essential YIL091C 571 - GTCACTTAGTGAGCCCTTTA D|197|H D|197|N S|196|T S|196|N UTP25 U Three Protein 721.0 0 1 0 0 -0.4759540392618724 P40498 0.11677836626768112 0.44109097123146057 0.4299294948577881 0.3347960710525513 53.548377959350546 45.0 0.0 no 5729 chrIX_192666 17696 essential YIL091C 510 - AACTTATCAACGAATTTCTC K|176|N silent|AAG>AAA|K|176 UTP25 U Three Protein 721.0 0 0 0 0 -0.3351114754250229 P40498 0.04860785230994225 36.54879627505903 30.0 0.0 no 5730 chrIX_192807 17701 essential YIL091C 369 - ATCTCCAATTGATCATCCAC E|129|D silent|GAG>GAA|E|129 E|129|Q E|129|K UTP25 U Three Protein 721.0 0 0 0 0 1.3889161524843303 P40498 0.2549787759780884 0.11931093782186508 0.1262420415878296 46.96426992198536 40.0 0.0 no 5731 chrIX_192848 17703 essential YIL091C 328 - GTGCTCATCCTCCCCAACTT E|115|D silent|GAG>GAA|E|115 E|115|Q E|115|K UTP25 U Three Protein 721.0 0 0 0 0 0.2582493876336549 P40498 0.2210034728050232 0.05240052193403244 0.18285483121871948 60.76204540102845 55.00000000000001 0.0 no 5732 chrIX_192976r 17708 essential YIL091C 197 + TTTCGATATTGAGGATGAAG F|67|L silent|TTC>TTT|F|67 UTP25 U Three Protein 721.0 0 1 0 0 -0.9987505539425064 P40498 0.2647326588630676 37.70437983037897 35.0 0.0 no 5733 chrIX_193016 17711 essential YIL091C 160 - ATCGGACACTTCATCCTCAT D|60|H D|60|N silent|GTG>GTC|V|58 silent|GTG>GTA|V|58 UTP25 U Three Protein 721.0 0 1 0 0 0.20664369616156114 P40498 0.06814808398485184 0.5082643628120422 50.55553808986997 45.0 0.0 no 5734 chrIX_193024 17712 essential YIL091C 152 - CTTCATCCTCATCGGATCTA E|57|Q E|57|K D|56|H D|56|N UTP25 U Three Protein 721.0 0 1 0 0 0.3384638197065837 P40498 0.5085352063179016 0.6375985145568848 0.18983985483646396 0.4709116220474243 50.73685673184025 45.0 0.0 no 5735 chrIX_203851 17714 essential YIL083C 783 - ACTAATCTTCTCAAAAACTT V|268|L V|268|M R|266|T R|266|K CAB2 Coenzyme A Biosynthesis 365.0 0 0 0 0 0.6256256554178906 P40506 0.9539830088615416 0.9587630033493042 0.932735025882721 0.955805003643036 0.017215671017766002 0.004480517003685236 0.5930982828140259 0.9437135457992554 34.62511811147391 25.0 0.0 no 5736 chrIX_204045 17720 essential YIL083C 589 - ACCACTATTATTCAATAGCT G|203|R G|203|S G|203|A G|203|D CAB2 Coenzyme A Biosynthesis 365.0 0 0 0 0 -2.0644353353646387 P40506 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.287784218788147 0.1950116902589798 0.09844755381345748 0.14891961216926575 42.26631448675085 30.0 0.0 yes 5737 chrIX_204101r 17723 essential YIL083C 530 + ACTTTTACTACCATTCACCA L|178|V L|178|F CAB2 Coenzyme A Biosynthesis 365.0 0 0 0 0 0.2888000486899073 P40506 0.9512209892272948 0.9587849974632264 0.03143400698900223 0.13737130165100098 47.165666783695485 35.0 0.0 no 5738 chrIX_204224r 17724 essential YIL083C 407 + TAGCATTAATACTTTATTCT S|137|R silent|AGC>AGT|S|137 CAB2 Coenzyme A Biosynthesis 365.0 0 0 0 0 0.8863923356253189 P40506 0.9417110085487366 0.09516558796167374 36.4284125708478 20.0 0.0 no 5739 chrIX_204426 17728 essential YIL083C 208 - AACTATTTTGTTCCTTTTCA V|76|L V|76|I CAB2 Coenzyme A Biosynthesis 365.0 0 0 0 0 -0.10636221098924993 P40506 0.9539830088615416 0.9574310183525084 0.01196351833641529 0.014701207168400288 42.63647916178081 25.0 0.0 no 5740 chrIX_204491 17730 essential YIL083C 143 - CATCGATATAGGCAGGTTTA D|54|H D|54|N CAB2 Coenzyme A Biosynthesis 365.0 0 0 0 0 -0.2879443287408011 P40506 0.9486550092697144 0.956179976463318 0.20081092417240146 0.4449280500411987 45.228218303965996 40.0 0.0 no 5741 chrIX_329356r 17737 no_effect YIL013C 3064 + AGCAATCTGATTCAATTAAC Q|1023|E Q|1023|* S|1024|C S|1024|F 0 0 0 0 -0.1407995839848635 P40550 0.9590039849281312 0.945252001285553 0.9294660091400146 0.05390240624547005 0.1055566743016243 36.625696036253096 30.0 0.0 no 5742 chrIX_329392 17738 no_effect YIL013C 3031 - TGGCTCATCAATTTTGCTTG E|1016|D silent|GAG>GAA|E|1016 E|1016|Q E|1016|K 0 0 0 0 0.662583427868236 P40550 0.94931298494339 0.956179976463318 0.9475290179252625 46.69479763175997 40.0 0.0 no 5743 chrIX_329355r 17740 no_effect YIL013C 3065 + GCAATCTGATTCAATTAACT Q|1023|E Q|1023|* S|1024|C S|1024|F 0 0 0 0 -0.09029339073236817 P40550 0.9590039849281312 0.945252001285553 0.9294660091400146 0.05390240624547005 0.1055566743016243 38.37549540996588 30.0 0.0 no 5744 chrIX_329417 17741 no_effect YIL013C 3006 - GGCTTCTCTGCATCATCCAT K|1008|N silent|AAG>AAA|K|1008 E|1007|D silent|GAG>GAA|E|1007 0 0 0 0 0.07300313908739295 P40550 0.9355990290641784 0.94931298494339 57.053166813921784 50.0 0.0 no 5745 chrIX_329582r 17744 no_effect YIL013C 2838 + AACATCTATTTACTAAAAAG N|947|K silent|AAC>AAT|N|947 I|948|M silent|ATC>ATT|I|948 0 0 0 0 0.3557848418545663 P40550 0.9439849853515624 0.9598389863967896 0.5667915940284729 0.03752653300762177 28.825882809508077 20.0 0.0 no 5746 chrIX_329722r 17747 no_effect YIL013C 2698 + TCCTAGATGAACCTACTTCA L|901|V silent|CTA>TTA|L|901 F|900|L silent|TTC>TTT|F|900 0 0 0 0 -0.483790576416955 P40550 0.9512209892272948 0.9387490153312684 0.0 0.2655577063560486 46.629240932611076 40.0 0.0 no 5747 chrIX_329816 17749 no_effect YIL013C 2607 - TCAGCAACCAGTTTTTCCGA D|876|H D|876|N A|875|P A|875|T 0 0 0 0 -0.4465935031073745 P40550 0.9486550092697144 0.956179976463318 0.9573720097541808 0.9523990154266356 0.052924036979675286 0.2722569406032562 0.2799643874168396 0.5907466411590576 51.35802780354413 45.0 0.0 no 5748 chrIX_329829 17750 no_effect YIL013C 2594 - TTTCCGAAGGCAATCTTAAT E|871|Q E|871|K silent|TCG>TCC|S|870 silent|TCG>TCA|S|870 0 0 0 0 1.4985134061218301 P40550 0.956179976463318 0.9475290179252625 0.5194658041000366 0.7723554968833923 42.53107885221573 35.0 0.0 no 5749 chrIX_329874 17751 no_effect YIL013C 2549 - CTCTATCCCCATCACCTCTT R|856|T R|856|K D|855|H D|855|N 0 0 0 0 -0.13697223440778122 P40550 0.932735025882721 0.955805003643036 0.9486550092697144 0.956179976463318 0.6195746660232544 0.7173715233802795 0.16144466400146484 0.3593117594718933 58.60517203833496 50.0 0.0 no 5750 chrIX_329881 17754 no_effect YIL013C 2542 - CCCATCACCTCTTAGGACGC G|854|R G|854|R G|854|A G|854|E 0 0 0 0 1.083329999741538 P40550 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.3256643116474152 0.3256643116474152 1.0 0.6421128511428833 57.600342773766954 60.0 0.0 no 5751 chrIX_330025 17756 no_effect YIL013C 2398 - ACCGGTAACAACCCCGCTTT G|806|R G|806|S G|806|A G|806|D 0 0 0 0 0.5868425535292155 P40550 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 55.281267763358024 55.00000000000001 0.0 no 5752 chrIX_330084 17760 no_effect YIL013C 2339 - CAGCACCAGATTCACCCATT A|786|P A|786|T G|785|A G|785|D 0 0 0 0 0.5925976271609853 P40550 0.9573720097541808 0.9523990154266356 0.9499930143356324 0.9446240067481996 0.02144310623407364 0.02252215147018433 0.0 0.0 54.354695503310325 50.0 0.0 no 5753 chrIX_330085 17761 no_effect YIL013C 2338 - AGCACCAGATTCACCCATTA A|786|P A|786|T G|785|A G|785|D 0 0 0 0 0.4126851797408614 P40550 0.9573720097541808 0.9523990154266356 0.9499930143356324 0.9446240067481996 0.02144310623407364 0.02252215147018433 0.0 0.0 52.63372936254712 45.0 0.0 no 5754 chrIX_330098r 17763 no_effect YIL013C 2322 + TCCGGATTAACTGCCCTAAT silent|TCC>TCG|S|775 silent|TCC>TCT|S|775 S|775|C S|775|F 0 0 0 0 0.5364618574513421 P40550 0.945252001285553 0.9294660091400146 0.0089424354955554 0.004455494228750467 49.83970533940185 45.0 0.0 no 5755 chrIX_330116r 17764 no_effect YIL013C 2304 + GCTTCTGGATATATAAGTTC A|769|G A|769|V S|770|C S|770|F 0 0 0 0 -0.9653276872030526 P40550 0.9484469890594482 0.9504740238189696 0.945252001285553 0.9294660091400146 0.0029307438526302576 1.0 0.02061138115823269 0.01893259771168232 41.83227322793198 35.0 0.0 no 5756 chrIX_330184r 17765 no_effect YIL013C 2236 + CGCAAAAGCACGTCATCTCC Q|747|E Q|747|* 0 0 0 0 -1.3577004762864395 P40550 0.9590039849281312 1.0 49.532150425608044 55.00000000000001 0.0 no 5757 chrIX_330356r 17768 no_effect YIL013C 2064 + AGCGCTATTACCAACAACGA S|689|R silent|AGC>AGT|S|689 A|690|G A|690|V 0 0 0 0 0.470992592218719 P40550 0.9417110085487366 0.9484469890594482 0.9504740238189696 0.509144127368927 0.3916212916374207 0.2795737981796265 45.83695376416471 45.0 0.0 no 5758 chrIX_330595 17769 no_effect YIL013C 1828 - TCTGACGTAATCGTTACCTA R|616|T R|616|K V|615|L V|615|I 0 0 0 0 0.1151876773629512 P40550 0.932735025882721 0.955805003643036 0.9539830088615416 0.9574310183525084 0.6378788948059082 0.9415511488914491 0.0 0.0 45.32935402930645 40.0 0.0 no 5759 chrIX_330628r 17772 no_effect YIL013C 1792 + TCAGTCATAAAGCTTGTGCC F|598|L silent|TTC>TTT|F|598 H|600|D H|600|Y 0 1 0 0 -0.31882642879421197 P40550 0.9387490153312684 0.9473130106925964 0.9489949941635132 0.7762767672538757 0.4642752110958099 1.0 48.73971956741354 45.0 0.0 no 5760 chrIX_330715 17774 no_effect YIL013C 1708 - AAACAATTCGTTACTCAAAA L|575|F silent|TTG>TTA|L|575 0 0 0 0 -0.5756017872234553 P40550 0.9587849974632264 1.0 32.77652948389857 25.0 0.0 no 5761 chrIX_330225r 17776 no_effect YIL013C 2195 + AACTGTTAACAATCATACTA T|733|S T|733|I 0 0 0 0 0.90021454251623 P40550 0.9491789937019348 0.9472420215606691 0.7630883455276489 0.22684486210346225 34.77181716156775 25.0 0.0 no 5762 chrIX_330796 17777 no_effect YIL013C 1627 - ATCTTTCATATAAATAACAT D|549|H D|549|N M|547|I M|547|I 0 0 0 0 0.9497212910004456 P40550 0.9486550092697144 0.956179976463318 0.9553959965705872 0.9553959965705872 0.09204887598752977 0.4144956469535828 0.3705908358097077 0.3705908358097077 30.982670634446894 15.0 0.0 no 5763 chrIX_330855r 17779 no_effect YIL013C 1565 + TCTATCAATGGCAAACCTAT L|523|V silent|CTA>TTA|L|523 S|524|* S|524|L 0 0 0 0 -1.0613410147033262 P40550 0.9512209892272948 0.9298099875450134 0.9270264506340028 0.3721368610858917 42.24615624663824 35.0 0.0 no 5764 chrIX_330963 17781 no_effect YIL013C 1460 - TAGCTGCATTGTACTGTAAA A|493|P A|493|T A|492|P A|492|T 0 0 0 0 -0.6059011525025279 P40550 0.9573720097541808 0.9523990154266356 0.9573720097541808 0.9523990154266356 0.06755632907152176 0.057843845337629325 0.1381060630083084 0.10955556482076644 42.55283655234007 35.0 0.0 no 5765 chrIX_331072r 17786 no_effect YIL013C 1348 + AGCTCCATTTTTATTATAAT L|451|V L|451|F silent|CTC>CTG|L|451 silent|CTC>CTT|L|451 0 0 0 0 0.4403328202636706 P40550 0.9512209892272948 0.9587849974632264 0.3206659555435181 0.6363199353218079 38.97671567294867 20.0 0.0 no 5766 chrIX_331120r 17788 no_effect YIL013C 1300 + ACATGCCTGCTTCCTTTCAA D|434|E silent|GAC>GAT|D|434 P|436|A P|436|S 0 0 0 0 0.27854868956097645 P40550 0.9532920122146606 0.9562489986419678 0.9498909711837769 1.0 1.0 0.5583913326263428 53.878793478307436 45.0 0.0 no 5767 chrIX_331193r 17789 no_effect YIL013C 1227 + ACAATTGGTTCGTTTTCTAG T|410|R T|410|I 0 0 0 0 0.3884233772901629 P40550 0.9476869702339172 0.9472420215606691 0.010526200756430626 0.06085478514432908 42.67901089870708 35.0 0.0 no 5768 chrIX_331202 17790 no_effect YIL013C 1221 - AACGAACCAATTGTTGTCAG silent|TCG>TCC|S|413 silent|TCG>TCA|S|413 G|412|A G|412|D 0 0 0 0 0.6713345614116265 P40550 0.9499930143356324 0.9446240067481996 0.04154608026146889 0.29210105538368225 41.325322870077684 40.0 0.0 no 5769 chrIX_331201 17791 no_effect YIL013C 1222 - AAACGAACCAATTGTTGTCA silent|TCG>TCC|S|413 silent|TCG>TCA|S|413 0 0 0 0 -0.41260265361696696 P40550 39.99834723079511 35.0 0.0 no 5770 chrIX_331414 17795 no_effect YIL013C 1009 - TTGCACTGTTTTTGAAGTGA silent|GTG>GTC|V|342 silent|GTG>GTA|V|342 V|342|L V|342|M 0 0 0 0 0.5115619480433433 P40550 0.9539830088615416 0.9587630033493042 0.3365741968154907 0.1175527125597 43.7169133205511 35.0 0.0 no 5771 chrIX_331468r 17797 no_effect YIL013C 952 + AAACAGATTTGCATACATTA T|319|R T|319|I 0 0 0 0 0.8369478538795607 P40550 0.9476869702339172 0.9472420215606691 0.5263649225234985 0.19670598208904266 35.986061356545235 25.0 0.0 no 5772 chrIX_331569r 17798 no_effect YIL013C 851 + AATCTTAAATTTTAAGTTCA I|285|M silent|ATC>ATT|I|285 0 0 0 0 0.43611907416703455 P40550 0.9598389863967896 0.018209559842944145 31.33691313213325 15.0 0.0 no 5773 chrIX_331858 17804 no_effect YIL013C 565 - CCATAAGTAAACAGACCCAT W|195|S W|195|* 0 0 0 0 -0.7698430546922305 P40550 0.8858469724655151 0.007786841131746769 43.842578169599456 40.0 0.0 no 5774 chrIX_332267r 17815 no_effect YIL013C 153 + ATCACTTTTCGTGCTAATGA I|52|M silent|ATC>ATT|I|52 T|53|S T|53|I 0 0 0 0 0.14730411729488746 P40550 0.9598389863967896 0.9491789937019348 0.9472420215606691 0.2683548033237457 0.7380182147026062 0.5464379787445068 43.89634199806693 35.0 0.0 no 5775 chrIX_332219r 17816 no_effect YIL013C 201 + CCAACATCAGCGCTCTTCAA P|68|R P|68|L T|69|R T|69|I 0 0 0 0 0.3566853247867683 P40550 0.9432820081710817 0.9430609941482544 0.9476869702339172 0.9472420215606691 0.05510655045509338 0.016317080706357956 0.033703088760375984 0.019474761560559276 50.83820650689898 50.0 0.0 no 5776 chrIX_332385r 17823 no_effect YIL013C 35 + CGCTTCAGTCACCTTTGATG A|13|G A|13|V S|14|* S|14|L 0 0 0 0 -0.18020169489407906 P40550 0.9484469890594482 0.9504740238189696 0.9298099875450134 0.24328847229480746 1.0 0.04053063690662384 51.22472603479854 50.0 0.0 no 5777 chrIX_332386r 17824 no_effect YIL013C 34 + ACGCTTCAGTCACCTTTGAT A|13|G A|13|V D|12|E silent|GAC>GAT|D|12 0 0 0 0 0.4943499072371724 P40550 0.9484469890594482 0.9504740238189696 0.9532920122146606 0.24328847229480746 1.0 0.0 51.7423338716755 45.0 0.0 no 5778 chrIX_332387r 17825 no_effect YIL013C 33 + GACGCTTCAGTCACCTTTGA D|12|E silent|GAC>GAT|D|12 A|13|G A|13|V 0 0 0 0 -0.30680974724335125 P40550 0.9532920122146606 0.9484469890594482 0.9504740238189696 0.0 0.24328847229480746 1.0 52.990359655600294 50.0 0.0 no 5779 chrIX_348187r 17828 essential YIL004C 165 + TCTCAAAGTGAGGAACAGAT Q|57|E Q|57|* S|56|C S|56|F 0 0 0 0 -0.36063737040487626 P22804 0.9590039849281312 0.945252001285553 0.9294660091400146 0.0 0.0 0.0 1.240365982055664 0.3520820140838623 -0.11944600194692613 40.27415577516837 40.0 0.0 no 5780 chrIX_348197r 17830 essential YIL004C 155 + ATCTCTTGAATCTCAAAGTG S|53|C S|53|F L|54|V L|54|F 0 0 0 0 0.7953196139402634 P22804 0.945252001285553 0.9294660091400146 0.9512209892272948 0.9587849974632264 0.031556729227304466 0.038639135658741 0.0 0.0 0.2898640036582947 0.04323400184512138 0.6016460061073303 0.2789140045642853 39.309575755888936 35.0 0.0 no 5781 chrIX_349139 17834 essential YIL003W 17 + AGGCGTTCCTGCGGCCTCTT silent|GGC>GGG|G|7 silent|GGC>GGT|G|7 CFD1 Cytosolic Fe-S cluster Deficient 293.0 0 0 0 0 -0.016717532712010718 P40558 65.34723002661644 65.0 1.0 no 5782 chrIX_349332 17844 essential YIL003W 210 + TCTATATATCAAGGTCCTGA S|71|C S|71|F CFD1 Cytosolic Fe-S cluster Deficient 293.0 0 0 0 0 0.6109292891393754 P40558 0.0290788933634758 0.02711549773812294 43.94500772227048 35.0 1.0 no 5783 chrIX_349347r 17845 essential YIL003W 228 - TTCACAGGTTGCCAACCTTC silent|GTG>GTC|V|82 silent|GTG>GTA|V|82 V|82|L V|82|M CFD1 Cytosolic Fe-S cluster Deficient 293.0 0 0 0 0 0.2221556919344007 P40558 0.03158983588218689 0.0015391741180792449 0.43299999833107 -1.1890000104904177 53.50306562284413 50.0 1.0 no 5784 chrIX_349392 17846 essential YIL003W 270 + TCTCTTAGTGTAATATCATT L|92|V L|92|F S|91|C S|91|F CFD1 Cytosolic Fe-S cluster Deficient 293.0 0 0 0 0 -0.15432799489083968 P40558 0.02302375249564648 0.0045012678019702435 0.08294499665498734 0.010293873958289623 0.8953999876976013 9.50220012664795 39.13358093353536 25.0 1.0 no 5785 chrIX_349588r 17853 essential YIL003W 469 - TACAATACCACCATCTGGTT V|163|L V|163|I CFD1 Cytosolic Fe-S cluster Deficient 293.0 0 0 0 0 0.4922602585243592 P40558 0.4765691161155701 1.0 47.44042399335103 40.0 1.0 no 5786 chrIX_349618r 17855 essential YIL003W 499 - AGCTGTTGCAACACTCTGTG A|173|P A|173|T CFD1 Cytosolic Fe-S cluster Deficient 293.0 0 0 0 0 0.04033862972352431 P40558 0.2726561427116394 0.5686172842979431 4.942200183868408 0.8040000200271606 50.58198132076615 50.0 1.0 no 5787 chrIX_349688r 17856 essential YIL003W 569 - ACATGTTTTCAATTATACCG M|196|I M|196|I CFD1 Cytosolic Fe-S cluster Deficient 293.0 0 0 0 0 1.315501782320082 P40558 0.0 0.0 -0.9315999746322632 -0.9315999746322632 39.95587809817579 30.0 1.0 no 5788 chrIX_349741 17858 essential YIL003W 619 + GTACAAATATCTTTTCCAGT T|208|R T|208|I CFD1 Cytosolic Fe-S cluster Deficient 293.0 0 1 0 0 0.9656150347518144 P40558 0.005518812220543623 0.00649277213960886 41.60246836543854 30.0 1.0 no 5789 chrIX_349743 17859 essential YIL003W 621 + ACAAATATCTTTTCCAGTGG T|208|R T|208|I CFD1 Cytosolic Fe-S cluster Deficient 293.0 0 1 0 0 -0.005664799253825625 P40558 0.005518812220543623 0.00649277213960886 42.10268998520746 35.0 1.0 no 5790 chrIX_349742 17860 essential YIL003W 620 + TACAAATATCTTTTCCAGTG T|208|R T|208|I CFD1 Cytosolic Fe-S cluster Deficient 293.0 0 1 0 0 0.156113686193022 P40558 0.005518812220543623 0.00649277213960886 39.17645833311701 30.0 1.0 no 5791 chrIX_366670 17863 essential YIR006C 3198 - ACATATTTTTCTTCTTGGAA V|1073|L V|1073|M PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 0 0 0 0.8559962623786186 P32521 39.5486709770986 25.0 0.0 no 5792 chrIX_366902 17869 essential YIR006C 2966 - ACGAGGAACGGTCATCTACA silent|TCG>TCC|S|995 silent|TCG>TCA|S|995 PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 0 0 0 0.030938855593009438 P32521 47.03412312913912 50.0 0.0 no 5793 chrIX_367038 17873 essential YIR006C 2830 - CCATCTTTCAAATTCTTGAT W|950|S W|950|* R|949|T R|949|K PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 0 0 0 -0.1079203790321012 P32521 41.52978305974091 30.0 0.0 no 5794 chrIX_367074 17874 essential YIR006C 2794 - TCCTGTCATAGTAGACTTCA G|938|R G|938|R G|938|A G|938|E PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 0 0 0 -0.2541349496503585 P32521 48.61400539145353 40.0 0.0 no 5795 chrIX_367075r 17875 essential YIR006C 2790 + TCCTTGAAGTCTACTATGAC silent|TCC>TCG|S|931 silent|TCC>TCT|S|931 S|931|C S|931|F PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 0 0 0 -0.08347793155036881 P32521 0.945252001285553 0.9294660091400146 0.0 0.0 43.99449422671961 40.0 0.0 no 5796 chrIX_367607r 17882 essential YIR006C 2258 + CCTTCAAACCGATGACATTT L|754|V L|754|F Q|755|E Q|755|* PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 1 0 0 0.4887804192890893 P32521 44.604394661111705 40.0 0.0 no 5797 chrIX_367864 17888 essential YIR006C 2004 - AAACTTGAAGGTAGGACATT S|674|T S|674|N PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 0 0 0 -0.7090125067391604 P32521 38.705843287079794 35.0 0.0 no 5798 chrIX_368197 17892 essential YIR006C 1671 - CCTGTCTTTTGGGCAGTCAA G|564|R G|564|R K|562|N silent|AAG>AAA|K|562 PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 1 0 0 -0.685892079631062 P32521 54.5537274272711 50.0 0.0 no 5799 chrIX_368197r 17893 essential YIR006C 1668 + CCGTTGACTGCCCAAAAGAC P|557|R P|557|L PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 0 0 0 0.2870340075447381 P32521 49.6683912344252 55.00000000000001 0.0 no 5800 chrIX_368324 17895 essential YIR006C 1544 - TACTTGCAGGACCGCTTTGC S|521|T S|521|N A|520|P A|520|T PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 0 0 0 0.7832813943074667 P32521 54.8269146852773 55.00000000000001 0.0 no 5801 chrIX_368335r 17898 essential YIR006C 1530 + TCCGTTATGCCCCAGCAAAG silent|TCC>TCG|S|511 silent|TCC>TCT|S|511 S|511|C S|511|F PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 0 0 1 0.19055936588030864 P32521 55.00017631445724 55.00000000000001 0.0 no 5802 chrIX_368368r 17901 essential YIR006C 1497 + GCTTTGCAATCTCAGTATAC A|500|G A|500|V Q|502|E Q|502|* PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 1 0 0 0.5948974672205023 P32521 0.9590039849281312 0.2787408530712128 45.73879799764707 40.0 0.0 no 5803 chrIX_368410r 17902 essential YIR006C 1455 + ACTTCATTTGGCGTTAATTT T|486|S T|486|I S|487|* S|487|L PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 1 0 0 -0.4008498365554428 P32521 0.9491789937019348 0.9472420215606691 1.0 0.27976036071777344 43.07810053590429 30.0 0.0 no 5804 chrIX_368488r 17903 essential YIR006C 1398 + GCTTTGCAACCTCAGACAAC A|467|G A|467|V Q|469|E Q|469|* PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 0 0 0 -0.4164732800389252 P32521 0.9484469890594482 0.9504740238189696 0.9590039849281312 0.5411422848701477 0.408975750207901 0.218761682510376 48.89723117225685 50.0 0.0 no 5805 chrIX_368515r 17904 essential YIR006C 1371 + TCTATGCAACCCAACATTAC S|458|C S|458|F Q|460|E Q|460|* PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 0 0 0 -0.4175186276152203 P32521 0.945252001285553 0.9294660091400146 0.9590039849281312 0.19339652359485626 0.6601596474647522 1.0 44.73659054133083 40.0 0.0 no 5806 chrIX_368586 17907 essential YIR006C 1303 - ATTCATTGACATGTTGAAAG M|440|I M|440|I PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 0 0 0 0.26809936726934475 P32521 0.9553959965705872 0.9553959965705872 0.4154138565063477 0.4154138565063477 36.16925380306401 30.0 0.0 no 5807 chrIX_368615r 17909 essential YIR006C 1271 + TCCTCAATCCACAGGATTTA P|425|R P|425|L P|425|A P|425|S PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 1 0 0 -1.5820344588590278 P32521 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.04139349237084389 0.020776772871613503 0.06382497400045395 0.04426474496722221 48.15023539952773 40.0 0.0 no 5808 chrIX_368662r 17912 essential YIR006C 1224 + CCATTACAGTCTCAAATTAC P|409|R P|409|L Q|411|E Q|411|* PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 0 0 0 0.4878827068963364 P32521 0.9432820081710817 0.9430609941482544 0.9590039849281312 0.010306031443178655 0.014257456175982954 0.04082435742020607 40.683143238774456 35.0 0.0 no 5809 chrIX_368704 17913 essential YIR006C 1185 - GGCATATATCCTGTTGGTTG M|401|I M|401|I PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 1 0 0 -0.0484663364257413 P32521 0.9553959965705872 0.9553959965705872 0.20221982896327967 0.20221982896327967 50.31586633779494 45.0 0.0 no 5810 chrIX_368854 17916 essential YIR006C 1035 - GTCTTAGAATCCAATTCGTA K|351|N silent|AAG>AAA|K|351 PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 0 0 0 1.2996432667218558 P32521 0.9355990290641784 0.014897007495164871 43.06967941614687 35.0 0.0 no 5811 chrIX_368855 17917 essential YIR006C 1034 - TCTTAGAATCCAATTCGTAA K|351|N silent|AAG>AAA|K|351 PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 0 0 0 0.24158109890865925 P32521 0.9355990290641784 0.014897007495164871 39.288806393429866 30.0 0.0 no 5812 chrIX_368864r 17918 essential YIR006C 1022 + TGACACTATCCCTTACGAAT D|342|E silent|GAC>GAT|D|342 T|343|S T|343|I PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 0 0 0 -0.16722495036894644 P32521 0.9532920122146606 0.9491789937019348 0.9472420215606691 0.04965735599398613 1.0 0.0119295259937644 45.39275187905486 40.0 0.0 no 5813 chrIX_368973r 17919 essential YIR006C 913 + CTTCTCAACTCGCAAGAATT S|306|C S|306|F Q|307|E Q|307|* PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 0 0 0 -0.791300009401543 P32521 0.945252001285553 0.9294660091400146 0.9590039849281312 0.01233725808560848 0.010215628892183304 0.03489784523844719 42.892923045923226 40.0 0.0 no 5814 chrIX_368911 17920 essential YIR006C 978 - TGCATTGCTAATGCAAATTC M|332|I M|332|I PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 0 0 0 0.2997790753360809 P32521 0.9553959965705872 0.9553959965705872 0.0 0.0 41.143694085162224 35.0 0.0 no 5815 chrIX_369055r 17922 essential YIR006C 831 + TTCAGATCAATTGTTACCAA F|278|L silent|TTC>TTT|F|278 PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 0 0 0 -0.5937714341203161 P32521 0.9387490153312684 0.0 40.458926057566536 30.0 0.0 no 5816 chrIX_369244r 17931 essential YIR006C 642 + CCTTTGAAGCCGCAGCAAAC P|215|R P|215|L PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 0 0 0 0.3411079709112141 P32521 0.9432820081710817 0.9430609941482544 0.03581903874874115 0.014467081055045128 50.58961038403504 55.00000000000001 0.0 no 5817 chrIX_369338r 17940 essential YIR006C 548 + TCAAACCCAGCAGCCCCTTC Q|184|E Q|184|* T|185|S T|185|I PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 0 0 0 0.2374183257803457 P32521 0.9590039849281312 0.9491789937019348 0.9472420215606691 1.0 1.0 0.2259461879730225 60.11944664341843 60.0 0.0 no 5818 chrIX_369397 17941 essential YIR006C 492 - CCTGTCCCTTGAGATTGCAA G|171|R G|171|R silent|GGG>GGC|G|169 silent|GGG>GGA|G|169 PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 1 0 0 -0.5676747491727296 P32521 0.941340982913971 0.941340982913971 0.4615367650985718 0.4615367650985718 54.06069628012562 50.0 0.0 no 5819 chrIX_369402r 17943 essential YIR006C 484 + TACAACCTTTGCAATCTCAA Q|163|E Q|163|* P|164|A P|164|S PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 0 0 0 0.1780675891349081 P32521 0.9590039849281312 0.9562489986419678 0.9498909711837769 0.6959383487701416 0.6802957057952881 0.5357138514518738 42.66605320740115 35.0 0.0 no 5820 chrIX_369469r 17945 essential YIR006C 417 + CTACAATCCATACAACCCCA Q|141|E Q|141|* PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 0 0 0 -0.3788612549386572 P32521 0.9590039849281312 1.0 49.264177701632995 45.0 0.0 no 5821 chrIX_369761r 17957 essential YIR006C 125 + GCCTCAACCACAACAGCAAA P|43|R P|43|L P|43|A P|43|S PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 0 0 0 -0.8432736010099285 P32521 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.6203429102897644 0.6648769378662109 1.0 0.8801618218421936 48.44566852168896 50.0 0.0 no 5822 chrIX_369835r 17959 essential YIR006C 51 + CAACAGCAGCAACAACCAAA Q|19|E Q|19|* Q|20|E Q|20|* PAN1 Poly(A)-binding protein-dependent poly(A) riboNuclease 1480.0 0 0 0 0 -0.09407840680404284 P32521 0.9590039849281312 0.9590039849281312 42.4205454911048 45.0 0.0 no 5823 chrIX_373489 17960 essential YIR008C 798 - TTCTCTTTGCTTGACCTCCT E|272|D silent|GAG>GAA|E|272 E|272|Q E|272|K PRI1 DNA PRImase 409.0 0 0 0 0 0.4193965431905107 P10363 0.33930617570877075 0.3410447537899017 0.4036563634872437 -0.14535999298095706 0.6165000200271606 0.9522600173950196 55.843111869701204 45.0 0.0 no 5824 chrIX_374178 17976 essential YIR008C 109 - AATCATATCCCTAGAAGGTT M|42|I M|42|I PRI1 DNA PRImase 409.0 0 1 0 0 -1.5509036117395645 P10363 0.024782255291938785 0.024782255291938785 1.3080999851226809 1.3080999851226809 44.3660768508974 35.0 0.0 no 5825 chrIX_374187r 17978 essential YIR008C 97 + ATCATTCGCCCAAACCTTCT H|34|D H|34|Y S|35|W S|35|L PRI1 DNA PRImase 409.0 0 0 0 0 -0.7267211348115605 P10363 0.12121859937906265 0.022155812010169033 0.010001854971051216 0.10536260157823564 8.832280158996582 4.952139854431152 -0.4766800105571747 0.2650200128555298 52.13752187824957 45.0 0.0 no 5826 chrIX_374186r 17979 essential YIR008C 98 + TCATTCGCCCAAACCTTCTA H|34|D H|34|Y S|35|W S|35|L PRI1 DNA PRImase 409.0 0 0 0 0 -2.4854548330943187 P10363 0.12121859937906265 0.022155812010169033 0.010001854971051216 0.10536260157823564 8.832280158996582 4.952139854431152 -0.4766800105571747 0.2650200128555298 51.642887134393504 45.0 0.0 yes 5827 chrIX_375492 17984 essential YIR010W 61 + ACAAACAAGTATACCCATTG H|21|Q silent|CAC>CAT|H|21 Q|23|E Q|23|* DSN1 Dosage Suppressor of NNF1 576.0 0 0 0 0 -0.10274743765046243 P40568 0.3405434191226959 0.6521979570388794 39.81764519792904 35.0 1.0 no 5828 chrIX_375658 17986 essential YIR010W 227 + ACACAAGAATAAACATATCC H|77|Q silent|CAC>CAT|H|77 H|77|D H|77|Y DSN1 Dosage Suppressor of NNF1 576.0 0 0 0 0 -0.3425492708089585 P40568 0.0 0.0 0.0 34.47140482938079 30.0 1.0 no 5829 chrIX_375659 17987 essential YIR010W 228 + CACAAGAATAAACATATCCA H|77|Q silent|CAC>CAT|H|77 DSN1 Dosage Suppressor of NNF1 576.0 0 0 0 0 0.19985030442498208 P40568 0.0 35.36371436974053 30.0 1.0 no 5830 chrIX_375914 17993 essential YIR010W 483 + CCTGCAATGATACCATATCC P|162|R P|162|L A|163|G A|163|V DSN1 Dosage Suppressor of NNF1 576.0 0 0 0 0 0.006028983413030736 P40568 0.3554912805557251 0.6494327187538147 0.3599678874015808 0.223244771361351 48.5719434271511 45.0 1.0 no 5831 chrIX_375986 17997 essential YIR010W 555 + TCGCAACCCACTGCTGCAGG Q|187|E Q|187|* S|186|W S|186|L DSN1 Dosage Suppressor of NNF1 576.0 0 0 0 0 -1.5560214602137197 P40568 0.927587628364563 0.08974052965641023 0.36110281944274897 58.52485697766224 65.0 1.0 no 5832 chrIX_376064r 18000 essential YIR010W 636 - GATCCGTACGGAAACAATTG G|218|A G|218|E G|218|R G|218|R DSN1 Dosage Suppressor of NNF1 576.0 0 0 0 0 -0.010605491032953884 P40568 41.61453698532426 45.0 1.0 no 5833 chrIX_376061 18001 essential YIR010W 630 + GCTCCGCAATTGTTTCCGTA P|212|A P|212|S A|211|G A|211|V DSN1 Dosage Suppressor of NNF1 576.0 0 0 0 0 -0.29859277773214943 P40568 0.21504072844982147 0.04932626709342003 0.458107978105545 0.19008229672908786 55.042609967703534 50.0 1.0 no 5834 chrIX_376223r 18004 essential YIR010W 795 - TCTTCAGGAATATCCTTGTG E|272|Q E|272|K E|271|Q E|271|K DSN1 Dosage Suppressor of NNF1 576.0 0 0 0 0 0.5559644490714438 P40568 0.2742895483970642 0.23831377923488614 0.22468292713165286 0.11793328076601027 45.63138368328526 40.0 1.0 no 5835 chrIX_377693 18012 essential YIR011C 534 - TGCAAATTTTCCAAACGTGG L|184|F silent|TTG>TTA|L|184 0 0 0 0 -0.2004893873805519 P38637 0.11020129919052124 41.93747972961029 40.0 0.0 no 5836 chrIX_377690 18013 essential YIR011C 537 - GCGTGCAAATTTTCCAAACG A|186|P A|186|T L|184|F silent|TTG>TTA|L|184 0 0 0 0 -1.2877391117629522 P38637 0.08435355126857758 0.08870697021484375 0.11020129919052124 44.161723377681646 45.0 0.0 no 5837 chrIX_377807 18014 essential YIR011C 420 - CTCTCATAAGACCTATTGTA E|146|D silent|GAG>GAA|E|146 E|146|Q E|146|K 0 0 0 0 -0.30394464413185457 P38637 0.6195063591003418 0.39932647347450256 0.6580421924591064 43.081189539911115 35.0 0.0 no 5838 chrIX_377817 18015 essential YIR011C 410 - ACCTATTGTAAGGTATGCTC R|143|T R|143|K R|143|S silent|AGG>AGA|R|143 0 0 0 0 -0.3666123002238684 P38637 0.018992867320775986 0.4907506406307221 0.01503194682300091 46.43668443489685 40.0 0.0 no 5839 chrIX_377818r 18016 essential YIR011C 406 + ACCAGAGCATACCTTACAAT Q|137|E Q|137|* Y|136|* silent|TAC>TAT|Y|136 0 0 0 0 -1.1786999257336443 P38637 1.0 46.53786908683196 40.0 0.0 no 5840 chrIX_377871r 18017 essential YIR011C 353 + CTTCAGTATACAAAAGTGTC F|119|L silent|TTC>TTT|F|119 0 0 0 0 0.004451136999006372 P38637 0.5889041423797607 38.16972298854454 35.0 0.0 no 5841 chrIX_377900r 18018 essential YIR011C 324 + AGCGTACATACGAGAGTCAT S|109|R silent|AGC>AGT|S|109 H|111|D H|111|Y 0 0 0 0 0.6251625548677617 P38637 0.3918679654598236 0.2951723635196686 0.4540395438671112 46.37602344471885 45.0 0.0 no 5842 chrIX_377955 18019 essential YIR011C 272 - CCACCAACAACTGCTGTAAT V|97|L V|97|M silent|GTG>GTC|V|97 silent|GTG>GTA|V|97 0 0 0 0 0.3310976053995353 P38637 0.6383257508277893 0.2329131364822388 46.66151976563794 45.0 0.0 no 5843 chrIX_378074 18028 essential YIR011C 153 - TTCATCACATTCTTGTTACG M|57|I M|57|I silent|GTG>GTC|V|56 silent|GTG>GTA|V|56 0 0 0 0 -0.24622030953514235 P38637 0.29024362564086914 0.29024362564086914 43.02793883172262 35.0 0.0 no 5844 chrIX_378541r 18035 essential YIR012W 58 - GTCTTGTTCGACCTCCACAG D|26|H D|26|N SQT1 Suppressor of QSR1 Truncations 431.0 0 0 0 0 -0.7540430755975359 P35184 0.9899479746818542 1.0004899501800537 0.03608182072639465 0.08169840276241302 55.34640903353983 55.00000000000001 1.0 no 5845 chrIX_378561 18036 essential YIR012W 75 + GACGTTCCCGTTGATATTGA D|26|E silent|GAC>GAT|D|26 P|28|A P|28|S SQT1 Suppressor of QSR1 Truncations 431.0 0 0 0 0 1.1079412815117284 P35184 0.9954699873924256 1.0004199743270874 0.9926369786262512 1.0 1.0 0.8028252124786377 49.42783834405526 45.0 1.0 no 5846 chrIX_378802r 18044 essential YIR012W 319 - AATCACAGATTCGCCATAAC silent|GTG>GTC|V|112 silent|GTG>GTA|V|112 V|112|L V|112|M SQT1 Suppressor of QSR1 Truncations 431.0 0 0 0 0 1.0527774700303385 P35184 0.9693499803543092 0.9784780144691468 0.04615536704659462 0.00915154255926609 1.8215179443359373 3.3036572933197017 42.80102924113498 40.0 1.0 no 5847 chrIX_378825 18045 essential YIR012W 339 + TCATGTTCTTTCACTTCTGA S|114|* S|114|L SQT1 Suppressor of QSR1 Truncations 431.0 0 0 0 0 0.5664617514269508 P35184 0.950007975101471 0.10452507436275482 2.6159799098968506 46.63934251580969 35.0 1.0 no 5848 chrIX_378975r 18050 essential YIR012W 492 - GCAAACGTCCTTGCTATAGT A|171|P A|171|T silent|ACG>ACC|T|169 silent|ACG>ACA|T|169 SQT1 Suppressor of QSR1 Truncations 431.0 0 0 0 0 -0.9657333983006179 P35184 1.0011199712753296 0.9935200214385986 0.0 0.0 7.291354179382324 0.4458180069923401 49.09283073873462 45.0 1.0 no 5849 chrIX_378967 18051 essential YIR012W 481 + AAACTCATCCCACTATAGCA T|162|S T|162|I H|163|D H|163|Y SQT1 Suppressor of QSR1 Truncations 431.0 0 0 0 0 0.8374157956402349 P35184 0.9554529786109924 0.9525889754295348 0.9669790267944336 0.9671300053596495 0.20712243020534515 0.5417578220367432 0.1977502554655075 0.16108188033103946 1.0453979969024658 1.2507319450378418 2.703399896621704 1.125767946243286 46.809523393926156 40.0 1.0 no 5850 chrIX_379003 18053 essential YIR012W 517 + GTGCAACTGATGGATCTGTT A|174|G A|174|V T|175|S T|175|I SQT1 Suppressor of QSR1 Truncations 431.0 0 0 0 0 -0.3684374192270161 P35184 0.9764879941940308 0.9757149815559388 0.9665899872779846 0.9646379947662354 0.1732562631368637 0.017012873664498333 0.7170995473861694 0.21831166744232175 1.0718439817428589 4.175858020782472 -0.7990959882736206 0.468207985162735 47.934842035563285 45.0 1.0 no 5851 chrIX_379082 18056 essential YIR012W 596 + ACACCAGCAAGATTGCTCTA H|200|Q silent|CAC>CAT|H|200 H|200|D H|200|Y SQT1 Suppressor of QSR1 Truncations 431.0 0 0 0 0 -0.25752231680097937 P35184 1.0024800300598145 0.9917020201683044 0.9918540120124816 0.0 0.0 0.0 3.68770170211792 6.029860019683838 5.320717811584473 49.32645189688582 45.0 1.0 no 5852 chrIX_379120r 18058 essential YIR012W 637 - CAGCGTATTTTCACCCTTGT silent|ACG>ACC|T|218 silent|ACG>ACA|T|218 SQT1 Suppressor of QSR1 Truncations 431.0 0 0 0 0 0.8669046634769738 P35184 53.24544041066793 45.0 1.0 no 5853 chrIX_379157 18059 essential YIR012W 671 + TTCTTTGGATAGCACTATTG S|225|C S|225|F SQT1 Suppressor of QSR1 Truncations 431.0 0 0 0 0 0.860135495269662 P35184 0.9634199738502502 0.9436050057411194 0.07641414552927017 0.008465156890451908 2.0170419216156006 43.796085357666016 42.77654738306677 35.0 1.0 no 5854 chrIX_379214 18062 essential YIR012W 728 + GATCACACAGGCAGAAATCA I|244|M silent|ATC>ATT|I|244 T|245|R T|245|I SQT1 Suppressor of QSR1 Truncations 431.0 0 0 0 0 0.7441972082138574 P35184 0.9661440253257751 0.9528260231018066 0.9646379947662354 0.09687834233045578 0.5294889211654663 0.1963973343372345 0.3415299952030182 0.1126200035214424 -0.5586159825325012 44.19742752053082 45.0 1.0 no 5855 chrIX_379248r 18064 essential YIR012W 765 - GCTAATGATAGGGAAATCCA A|262|P A|262|T SQT1 Suppressor of QSR1 Truncations 431.0 0 0 0 0 -1.6536647186258182 P35184 0.9644709825515748 0.955838978290558 0.3918772339820862 0.7573032379150391 6.801539897918701 2.9322729110717773 42.54914333837871 40.0 1.0 no 5856 chrIX_379272r 18067 essential YIR012W 789 - TTACCCTTGGTCAAAGTTTC G|269|A G|269|D G|269|R G|269|S SQT1 Suppressor of QSR1 Truncations 431.0 0 0 0 0 -0.5887757655478755 P35184 0.9434890151023864 0.9316660165786744 0.9264810085296632 0.9447289705276488 3.106105089187622 3.4349565505981445 3.2173428535461426 3.434770345687866 47.44403773381094 40.0 1.0 no 5857 chrIX_379277 18068 essential YIR012W 791 + AACTTTGACCAAGGGTAACT T|265|S T|265|I SQT1 Suppressor of QSR1 Truncations 431.0 0 0 0 0 0.18408147542997186 P35184 0.9513729810714722 0.9485089778900146 0.7449239492416382 0.1695653647184372 -0.1315159946680069 -0.3353840112686157 43.411436145347004 40.0 1.0 no 5858 chrIX_379318r 18073 essential YIR012W 835 - TACTGCCAGAAGACCATTGT V|285|L V|285|I A|284|P A|284|T SQT1 Suppressor of QSR1 Truncations 431.0 0 0 0 0 -0.17040444008904135 P35184 0.9580950140953064 0.9656739830970764 0.9770879745483398 0.9687960147857666 0.4764381051063538 1.0 0.1941099762916565 0.3833678066730499 3.1192739009857178 -0.4883959889411926 7.0958499908447275 0.8117380142211914 49.03731321092431 45.0 1.0 no 5859 chrIX_379335 18074 essential YIR012W 849 + GCAGTAATTAATTGTAACAA A|284|G A|284|V SQT1 Suppressor of QSR1 Truncations 431.0 0 0 0 0 -0.3671474407468664 P35184 0.9672009944915771 0.9664270281791688 0.29095613956451416 0.5624154806137085 1.8614000082015991 -0.4761799871921539 34.323421750139396 25.0 1.0 no 5860 chrIX_379398r 18075 essential YIR012W 915 - GCATCTAATTCGTCTTGTTC A|312|P A|312|T D|311|H D|311|N SQT1 Suppressor of QSR1 Truncations 431.0 0 0 0 0 0.3614343723984405 P35184 0.96628999710083 0.9576590061187744 0.965224027633667 0.97645902633667 0.2743940353393555 0.5726783275604248 0.038662657141685486 0.13921231031417847 6.585450172424316 1.4469660520553589 -0.9946399927139282 -0.3063139915466309 46.871962020918595 40.0 1.0 no 5861 chrIX_379420 18076 essential YIR012W 934 + CCTCCATTGAATCCATTTCT S|313|C S|313|F silent|GCC>GCG|A|312 silent|GCC>GCT|A|312 SQT1 Suppressor of QSR1 Truncations 431.0 0 0 0 0 -0.3849118535113797 P35184 0.9634199738502502 0.9436050057411194 0.01810320653021336 0.008786541409790516 0.9033420085906982 13.407164573669435 50.25299895635567 40.0 1.0 no 5862 chrIX_379442 18077 essential YIR012W 956 + GTCATCCAAATTCTCCCTTA S|320|* S|320|L S|321|C S|321|F SQT1 Suppressor of QSR1 Truncations 431.0 0 0 0 0 -0.7537797861856621 P35184 0.9508730173110962 0.9534689784049988 0.9306049942970276 0.0941862016916275 0.05803653597831726 0.05800391733646393 0.7573360204696655 -0.07690200209617615 -0.8243520259857178 50.33073579040314 40.0 1.0 no 5863 chrIX_382003 18080 essential YIR015W 55 + CTCTGCTAGTACCGCCACCA L|20|V silent|CTG>TTG|L|20 L|21|V silent|CTA>TTA|L|21 RPR2 RNase P Ribonucleoprotein 144.0 0 0 0 0 -1.712767058587915 P40571 0.1112205758690834 0.19267435371875766 60.1803789698626 60.0 1.0 no 5864 chrIX_382136 18084 essential YIR015W 188 + ACGCAATTATATCAAATCAA silent|CGC>CGG|R|64 silent|CGC>CGT|R|64 R|64|G R|64|C RPR2 RNase P Ribonucleoprotein 144.0 0 0 0 0 -0.5359986150089264 P40571 0.0 0.0 34.67508979244536 25.0 1.0 no 5865 chrIX_378661r 18089 essential YIR012W 178 - GTCTGTGTGCTTATCGAAAT D|66|H D|66|N SQT1 Suppressor of QSR1 Truncations 431.0 0 0 0 0 0.33880583201324804 P35184 0.950190007686615 0.961425006389618 0.01370903570204973 0.0699567049741745 0.3855319917201996 -0.26340600848197937 45.13730561731518 40.0 1.0 no 5866 chrIX_398838r 18093 essential YIR022W 108 - CCTGAAAGCACCACCACGAT G|43|R G|43|S SEC11 SECretory 167.0 0 1 0 0 -2.285744000968454 P15367 0.9297440052032472 0.9479920268058776 0.01097983680665493 0.02999894134700298 51.19955626612103 55.00000000000001 1.0 yes 5867 chrIX_398971 18100 essential YIR022W 238 + CCATTGTGCATAGAGTTTTG silent|CCC>CCG|P|80 silent|CCC>CCT|P|80 SEC11 SECretory 167.0 0 0 0 0 -0.044755521762740655 P15367 46.25177237035621 40.0 1.0 no 5868 chrIX_399093 18103 essential YIR022W 360 + AACAAGTCAAAGGAGATTGT N|121|K silent|AAC>AAT|N|121 SEC11 SECretory 167.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.2575906293335484 P15367 0.9230020046234132 0.4541463851928711 37.68645477842768 35.0 1.0 no 5869 chrX_53347r 18104 essential YJL203W 9 - TCTTTCAGCTGGGTATCTTC E|10|Q E|10|K silent|CTG>CTC|L|8 silent|CTG>CTA|L|8 PRP21 Pre-mRNA Processing 280.0 0 0 0 0 -1.4137261954454414 P32524 0.13898523151874542 0.3721684217453003 52.07525618971982 45.0 1.0 no 5870 chrX_53671 18110 essential YJL203W 330 + GAACAGATGATTTCAAAGGA Q|112|E Q|112|* PRP21 Pre-mRNA Processing 280.0 0 0 0 0 -0.1205871807081512 P32524 1.0 36.95964959962856 35.0 1.0 no 5871 chrX_53909 18113 essential YJL203W 568 + TACAATTTGCAGCCATTCCA Q|191|E Q|191|* PRP21 Pre-mRNA Processing 280.0 0 0 0 0 -0.41818833714561465 P32524 0.3798161745071411 1.3769999742507937 49.48291767355 40.0 1.0 no 5872 chrX_57063 18117 no_effect YJL200C 1731 - TTCAATTCCTTCCCGTTCCA L|583|F silent|TTG>TTA|L|583 ACO2 ACOnitase 789.0 0 1 0 0 0.39819574156656334 P39533 0.9587849974632264 0.6466665863990784 55.77958329642172 45.0 0.0 no 5873 chrX_57138 18121 no_effect YJL200C 1656 - TCTACATTGCTATCTGGCTT E|559|Q E|559|K V|558|L V|558|I ACO2 ACOnitase 789.0 0 0 0 0 0.012667567220632465 P39533 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.5895516872406006 0.3650466203689575 0.23966944217681885 0.2937415838241577 49.615833666898205 40.0 0.0 no 5874 chrX_57189 18122 no_effect YJL200C 1605 - CCGTGTTCAAATCCTCTTTT G|542|R G|542|S ACO2 ACOnitase 789.0 0 1 0 0 -0.16596289230777986 P39533 0.941340982913971 0.951104998588562 0.0025884381029754877 0.064577117562294 48.95883108745159 40.0 0.0 no 5875 chrX_57223r 18124 no_effect YJL200C 1568 + TTTCAAATTCCAACCACCAA F|524|L silent|TTC>TTT|F|524 ACO2 ACOnitase 789.0 0 0 0 0 -0.11535741694214804 P39533 0.9387490153312684 0.06536909937858583 43.67911504272252 35.0 0.0 no 5876 chrX_57252r 18125 no_effect YJL200C 1539 + GACTCAATTAAATTGCCAAA D|514|E silent|GAC>GAT|D|514 S|515|* S|515|L ACO2 ACOnitase 789.0 0 0 0 0 -0.03285088538470005 P39533 0.9532920122146606 0.9298099875450134 0.0 0.048094477504491806 37.07155525910122 30.0 0.0 no 5877 chrX_57309 18126 no_effect YJL200C 1485 - CTCATCGCTGTTACTATTTC M|501|I M|501|I silent|GCG>GCC|A|500 silent|GCG>GCA|A|500 ACO2 ACOnitase 789.0 0 0 0 0 0.2357748784254933 P39533 0.9553959965705872 0.9553959965705872 0.18145346641540527 0.18145346641540527 46.55796304658549 40.0 0.0 no 5878 chrX_57310 18127 no_effect YJL200C 1484 - TCATCGCTGTTACTATTTCT M|501|I M|501|I silent|GCG>GCC|A|500 silent|GCG>GCA|A|500 ACO2 ACOnitase 789.0 0 0 0 0 -0.04872930474162772 P39533 0.9553959965705872 0.9553959965705872 0.18145346641540527 0.18145346641540527 46.55796304658549 35.0 0.0 no 5879 chrX_57670 18137 no_effect YJL200C 1124 - TCAAACCAGCGCTAACTTTT L|381|F silent|TTG>TTA|L|381 G|380|A G|380|D ACO2 ACOnitase 789.0 0 1 0 0 -0.4406391212434421 P39533 0.9587849974632264 0.9499930143356324 0.9446240067481996 0.027771733701229092 0.460246205329895 0.005414667073637247 45.39934570626315 40.0 0.0 no 5880 chrX_57672 18138 no_effect YJL200C 1122 - AAACCAGCGCTAACTTTTTG G|380|A G|380|D G|380|R G|380|S ACO2 ACOnitase 789.0 0 0 0 0 0.1859497937387377 P39533 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.460246205329895 0.005414667073637247 0.004974612034857272 0.16038450598716736 43.53192305220313 40.0 0.0 no 5881 chrX_57762r 18141 no_effect YJL200C 1029 + GCAATTGAACCTCACGTTAA A|344|G A|344|V ACO2 ACOnitase 789.0 0 0 0 0 0.32495321146857675 P39533 0.9484469890594482 0.9504740238189696 0.06670374423265457 0.046929512172937386 43.49900516754371 40.0 0.0 no 5882 chrX_58011r 18145 no_effect YJL200C 780 + ATCGTCGAGTACTTCGGCGA I|261|M silent|ATC>ATT|I|261 silent|GTC>GTG|V|262 silent|GTC>GTT|V|262 ACO2 ACOnitase 789.0 0 0 0 0 0.2877494658045687 P39533 0.9598389863967896 0.0013852148549631238 52.258835129468316 55.00000000000001 0.0 no 5883 chrX_57982r 18146 no_effect YJL200C 809 + CACTCTATCTTGCACAGGTA T|271|S T|271|I L|272|V silent|CTA>TTA|L|272 ACO2 ACOnitase 789.0 0 0 0 0 -0.061068405422108375 P39533 0.9491789937019348 0.9472420215606691 0.9512209892272948 0.979881465435028 0.007202547509223224 0.026930805295705795 49.569359253435316 45.0 0.0 no 5884 chrX_58071 18148 no_effect YJL200C 723 - AGCTTTGTGATTACATCTTT K|247|N silent|AAG>AAA|K|247 ACO2 ACOnitase 789.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.5123976908267542 P39533 0.9355990290641784 0.09975344687700273 43.73055709794846 30.0 0.0 no 5885 chrX_58097 18149 no_effect YJL200C 697 - GGACCATCCGTTTAACTTTC W|238|C W|238|* W|238|S W|238|* ACO2 ACOnitase 789.0 0 0 0 0 0.3613905748210576 P39533 0.8858469724655151 0.8858469724655151 0.0 0.0 49.101186682374866 45.0 0.0 no 5886 chrX_58100r 18150 no_effect YJL200C 691 + TGACCGGAAAGTTAAACGGA T|232|S T|232|I silent|ACC>ACG|T|232 silent|ACC>ACT|T|232 ACO2 ACOnitase 789.0 0 1 0 0 -0.05986137439692299 P39533 0.9491789937019348 0.9472420215606691 0.07018765807151794 0.004982417449355125 41.55638074006527 45.0 0.0 no 5887 chrX_58153 18151 no_effect YJL200C 641 - ATTCCCATGGAGTGCCTGTG E|220|Q E|220|K W|219|C W|219|* ACO2 ACOnitase 789.0 0 0 0 0 0.6226805770621678 P39533 0.956179976463318 0.9475290179252625 0.8858469724655151 0.005074895918369293 0.004005105700343847 0.0010819530580192804 57.599367821746796 55.00000000000001 0.0 no 5888 chrX_58288r 18162 no_effect YJL200C 503 + TATCATTCACCAGATTGTTT I|169|M silent|ATC>ATT|I|169 ACO2 ACOnitase 789.0 0 0 0 0 0.4233728743190025 P39533 0.9598389863967896 0.0 43.65644968556154 30.0 0.0 no 5889 chrX_58360 18163 no_effect YJL200C 434 - CCAAGAAATCGAAAACTTCT L|151|F silent|TTG>TTA|L|151 ACO2 ACOnitase 789.0 0 0 0 0 0.9076982980663476 P39533 0.9587849974632264 0.004511076956987381 36.59996557967361 35.0 0.0 no 5890 chrX_58482r 18167 no_effect YJL200C 309 + CTTCTACAATTCATGACCAC L|105|V silent|CTA>TTA|L|105 Q|106|E Q|106|* ACO2 ACOnitase 789.0 0 0 0 0 -0.5329647877331516 P39533 0.9512209892272948 0.9590039849281312 0.006103587802499533 0.005329643841832876 43.61372429943617 40.0 0.0 no 5891 chrX_58519 18168 no_effect YJL200C 275 - AAGCGTCCTGCATAGCTACA A|98|P A|98|T D|97|H D|97|N ACO2 ACOnitase 789.0 0 0 0 0 0.8221554853600479 P39533 0.9573720097541808 0.9523990154266356 0.9486550092697144 0.956179976463318 0.006091695744544268 0.0041897823102772245 0.002483958611264825 0.012050204910337923 52.862198713069354 50.0 0.0 no 5892 chrX_58552 18172 no_effect YJL200C 242 - GCTTCAAGTATTTATTACCA K|87|N silent|AAG>AAA|K|87 L|86|F silent|TTG>TTA|L|86 ACO2 ACOnitase 789.0 0 0 0 0 0.7779615432038465 P39533 0.9355990290641784 0.9587849974632264 0.02379961870610714 0.005762757733464241 43.00582331993411 30.0 0.0 no 5893 chrX_58569r 18173 no_effect YJL200C 222 + TCTGATCTGTCCACCATCCG S|75|C S|75|F L|77|V silent|CTG>TTG|L|77 ACO2 ACOnitase 789.0 0 0 0 0 -0.01260504058202895 P39533 0.945252001285553 0.9294660091400146 0.9512209892272948 0.184869721531868 0.7134310007095337 0.28803613781929016 56.12944334713626 55.00000000000001 0.0 no 5894 chrX_69359r 18175 essential YJL194W 24 - TTTCTTCTGATACGCTTAGT R|14|T R|14|K R|13|T R|13|K 0 0 0 0 -1.3386614565033983 P09119 0.9657250046730042 0.9840949773788452 0.9640290141105652 0.9823979735374452 0.5775856375694275 0.9552758932113647 0.14552049338817594 1.0 45.76248304665774 35.0 1.0 no 5895 chrX_69542 18179 essential YJL194W 204 + GTCAACTTGAATAGCAGCGA silent|GTC>GTG|V|69 silent|GTC>GTT|V|69 N|70|K silent|AAC>AAT|N|70 0 0 0 0 0.19274354329600013 P09119 0.96908301115036 45.33310803250942 45.0 1.0 no 5896 chrX_69638 18181 essential YJL194W 300 + TCCGATTCACTGTACATCAC silent|TCC>TCG|S|101 silent|TCC>TCT|S|101 S|101|C S|101|F 0 0 0 0 -0.31412459709206564 P09119 0.9634199738502502 0.9436050057411194 0.03662645071744919 0.01707226037979126 47.783692200425996 45.0 1.0 no 5897 chrX_69733 18187 essential YJL194W 395 + GCTCTCCACGCCACGCTCGA silent|CTC>CTG|L|133 silent|CTC>CTT|L|133 L|133|V L|133|F 0 0 0 0 0.7632964954763417 P09119 0.9703750014305116 0.9798439741134644 0.5042374134063721 0.4572948515415192 63.143181030001536 70.0 1.0 no 5898 chrX_69810r 18191 essential YJL194W 475 - CACGGATTCTAGCCTTCCAT V|165|L V|165|M 0 0 0 0 -0.5156548412760009 P09119 0.9693499803543092 0.9784780144691468 0.06301933526992798 0.011806177906692028 53.85857093503303 50.0 1.0 no 5899 chrX_69876r 18194 essential YJL194W 541 - ATCGAAAATCTTCTGGAAAA D|187|H D|187|N 0 0 0 0 0.7477099769760641 P09119 0.965224027633667 0.97645902633667 0.13052821159362793 0.4977818727493286 34.38034713616014 30.0 1.0 no 5900 chrX_69968r 18197 essential YJL194W 633 - AACGTAGTTTTCTTATGATA silent|ACG>ACC|T|217 silent|ACG>ACA|T|217 0 0 0 0 0.5530882856358176 P09119 37.77650393774393 25.0 1.0 no 5901 chrX_70261 18203 essential YJL194W 923 + CACTATTATCTTCCAACCGA T|309|S T|309|I 0 0 0 0 0.12262876673750925 P09119 0.9665899872779846 0.9646379947662354 0.5852420926094055 0.16859762370586395 46.250790739096935 40.0 1.0 no 5902 chrX_70284r 18204 essential YJL194W 949 - CTTCTTTGCTGCGAATTTGA K|322|N silent|AAG>AAA|K|322 0 0 0 0 0.8947022181107218 P09119 0.9665650129318236 0.023299654945731163 46.339636899039995 40.0 1.0 no 5903 chrX_69795r 18205 essential YJL194W 460 - TCCATCGGGCAATTCAAACC G|160|R G|160|R G|160|A G|160|E 0 0 0 0 -2.1216653779008543 P09119 0.9477360248565674 0.9477360248565674 0.9656509757041932 0.9509360194206238 0.03718676418066025 0.03718676418066025 0.055303443223237984 0.07620400190353394 49.14076930824894 50.0 1.0 yes 5904 chrX_70388 18207 essential YJL194W 1050 + TTTCTGCTTTCACCAACAAG L|352|V silent|CTG>TTG|L|352 L|353|V L|353|F 0 1 0 0 -0.6160442000780006 P09119 0.9534149765968324 0.959119975566864 0.9684990048408508 0.5555720925331116 0.5495321750640869 0.3324263095855713 45.20425070017956 40.0 1.0 no 5905 chrX_70334 18208 essential YJL194W 996 + AAACTTTTTGATGTCTTAAG L|334|V L|334|F 0 0 0 0 0.6721258941166419 P09119 0.9148989915847778 0.9236630201339722 0.5039512515068054 0.11146462708711624 34.40535815057484 25.0 1.0 no 5906 chrX_70472 18209 essential YJL194W 1134 + CCAGAACCACAAGGTAAAAT P|379|R P|379|L P|381|A P|381|S 0 0 0 0 0.5294097386756071 P09119 0.95032000541687 0.9589239954948424 0.9650480151176452 0.9562280178070068 0.5254899263381958 0.35354793071746826 0.7712257504463196 0.9182974100112916 40.41410406159884 40.0 1.0 no 5907 chrX_70492 18210 essential YJL194W 1154 + AGGCTTGAACTACATAGCCA silent|GGC>GGG|G|386 silent|GGC>GGT|G|386 0 0 0 0 -0.9067464109060848 P09119 48.8381342713326 45.0 1.0 no 5908 chrX_84080r 18212 high_effect YJL183W 15 - TACGTTTTGCCCTTCGTTCT silent|ACG>ACC|T|11 silent|ACG>ACA|T|11 MNN11 MaNNosyltransferase 422.0 0 0 0 0 0.4752465836410766 P46985 54.74452512874916 45.0 1.0 no 5909 chrX_84097 18213 high_effect YJL183W 29 + AACGTACTCCTCAAGATCGG T|11|R T|11|M Y|12|* silent|TAC>TAT|Y|12 MNN11 MaNNosyltransferase 422.0 0 0 0 0 -0.9665633850627406 P46985 0.9476869702339172 0.9502379894256592 0.6374380588531494 0.219590425491333 46.76640412236139 50.0 1.0 no 5910 chrX_84105r 18214 high_effect YJL183W 40 - CTGCGAACCCACCGATCTTG silent|TCG>TCC|S|19 silent|TCG>TCA|S|19 MNN11 MaNNosyltransferase 422.0 0 0 0 0 0.4714653344012015 P46985 53.57492736808234 60.0 1.0 no 5911 chrX_84233 18218 high_effect YJL183W 165 + TATCCAATTTCTCGTTCCGC P|57|A P|57|S P|57|R P|57|L MNN11 MaNNosyltransferase 422.0 0 0 0 0 -0.16060873690702154 P46985 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.579491376876831 0.5412612557411194 0.3835127651691437 0.6370702385902405 51.07921311688466 45.0 1.0 no 5912 chrX_84258 18219 high_effect YJL183W 190 + CATCATATTCTCCATCCCAT S|65|* S|65|L MNN11 MaNNosyltransferase 422.0 0 0 0 0 -0.5836903856067636 P46985 0.9298099875450134 0.33618608117103577 51.39817624788606 40.0 1.0 no 5913 chrX_84257 18220 high_effect YJL183W 189 + GCATCATATTCTCCATCCCA A|64|G A|64|V S|65|* S|65|L MNN11 MaNNosyltransferase 422.0 0 0 0 0 -0.2754274389106149 P46985 0.9484469890594482 0.9504740238189696 0.9298099875450134 0.3503825068473816 0.5381234884262085 0.33618608117103577 55.16975456784672 45.0 1.0 no 5914 chrX_84291 18222 high_effect YJL183W 223 + ACGAAATTCCTGCCTCCAGC N|75|K silent|AAC>AAT|N|75 MNN11 MaNNosyltransferase 422.0 0 0 0 0 -0.35408443077397256 P46985 0.9439849853515624 0.0781719982624054 54.35495487298772 55.00000000000001 1.0 no 5915 chrX_84341r 18224 high_effect YJL183W 276 - ACGGTCATTTGTTTTAACAC V|99|L V|99|I M|97|I M|97|I MNN11 MaNNosyltransferase 422.0 0 0 0 0 0.9873295314947916 P46985 0.9539830088615416 0.9574310183525084 0.9553959965705872 0.9553959965705872 0.8586407303810121 1.0 0.3641262948513031 0.3641262948513031 42.07942363259917 35.0 1.0 no 5916 chrX_84422r 18227 high_effect YJL183W 357 - TCTGTCAAAGCATTCTCTTC D|126|H D|126|N L|124|F silent|TTG>TTA|L|124 MNN11 MaNNosyltransferase 422.0 0 0 0 0 0.4036749078788056 P46985 0.9486550092697144 0.956179976463318 0.9587849974632264 0.07870543748140335 0.2968483567237854 0.7539466619491577 46.040902457926684 40.0 1.0 no 5917 chrX_84502r 18228 high_effect YJL183W 437 - TCCGATACACTAATTTACCA R|152|P R|152|Q silent|CGG>CGC|R|152 silent|CGG>CGA|R|152 MNN11 MaNNosyltransferase 422.0 0 0 0 0 -0.2497367398492293 P46985 0.9099509716033936 0.949662983417511 0.2539753019809723 0.3676523566246033 43.54423259440779 35.0 1.0 no 5918 chrX_84637r 18231 high_effect YJL183W 572 - AACGAATGTATACACCATAT R|197|P R|197|H MNN11 MaNNosyltransferase 422.0 0 0 0 0 0.3188595341837478 P46985 0.9099509716033936 0.9570810198783876 0.012539489194750786 0.013548715971410276 37.95456096182778 30.0 1.0 no 5919 chrX_84765r 18232 high_effect YJL183W 700 - ATCAACAAAATGAATATACT D|240|H D|240|N V|239|L V|239|I MNN11 MaNNosyltransferase 422.0 0 1 0 0 0.4344900424487357 P46985 0.9486550092697144 0.956179976463318 0.9539830088615416 0.9574310183525084 0.0051979292184114465 0.015382799319922926 1.0 0.17501141130924225 29.824756884207034 20.0 1.0 no 5920 chrX_84832 18233 high_effect YJL183W 764 + CCTGTTAGATCCAAAGATTA L|256|V silent|CTG>TTG|L|256 MNN11 MaNNosyltransferase 422.0 0 1 0 0 0.9984362754140012 P46985 0.9512209892272948 0.05968234315514565 42.51627326810558 35.0 1.0 no 5921 chrX_90998r 18239 essential YKL180W 215 - TGACACCAAATTCCTTACCT V|78|L V|78|I G|77|A G|77|D 0 1 0 0 0.7026249067058126 P05740 0.9539830088615416 0.9574310183525084 0.9499930143356324 0.9446240067481996 0.6604101657867432 0.4019313752651215 0.03337157145142555 0.11594486981630325 -0.4406000077724457 -0.3144800066947937 3.7195000648498535 3.870620012283325 47.2462010597219 40.0 1.0 no 5922 chrX_92685r 18240 high_effect YJL176C 1823 + ATCAACAATAGCATTCTTGG S|609|* S|609|L T|610|R T|610|I SWI3 SWItching deficient 825.0 0 0 0 0 -2.4618874706408125 P32591 0.0 0.0 0.0 40.473835021130746 35.0 0.0 yes 5923 chrX_92837 18246 high_effect YJL176C 1674 - AAACGTAAGATACACTGTTC R|564|P R|564|H SWI3 SWItching deficient 825.0 0 0 0 0 -1.3921617816624028 P32591 0.012474660761654377 0.013669840060174463 37.16623249942046 35.0 0.0 no 5924 chrX_92860 18247 high_effect YJL176C 1651 - CGACTTATTGCCAACGTTTT K|556|N silent|AAG>AAA|K|556 SWI3 SWItching deficient 825.0 0 0 0 0 0.7926073786522501 P32591 0.0 46.03083554170758 40.0 0.0 no 5925 chrX_93015r 18255 high_effect YJL176C 1493 + GACTGGTGATGCCAATCTAT T|499|S T|499|I SWI3 SWItching deficient 825.0 0 0 0 0 -0.3493158011230515 P32591 0.7287099361419678 0.18317607045173645 48.31753986131911 45.0 0.0 no 5926 chrX_93286r 18261 high_effect YJL176C 1222 + TAACGTCTCAATATTCCACA T|409|R T|409|M S|410|C S|410|F SWI3 SWItching deficient 825.0 0 0 0 0 0.2216776980780869 P32591 0.0 0.0 0.04386252909898758 0.028698125854134563 42.62684865152306 35.0 0.0 no 5927 chrX_93367r 18262 high_effect YJL176C 1141 + TGCATAAATTCTTAACAAAA H|382|D H|382|Y SWI3 SWItching deficient 825.0 0 0 0 0 0.59728176429285 P32591 0.0 0.0 2.6938800811767583 0.5102000236511229 30.84059277869125 20.0 0.0 no 5928 chrX_93438 18264 high_effect YJL176C 1073 - TGACACTGAAATATTCGTTG V|364|L V|364|I S|363|T S|363|N SWI3 SWItching deficient 825.0 0 0 0 0 1.1120449973949942 P32591 0.0 0.0 0.8097890019416809 0.0830024853348732 -1.243880033493042 -1.0425000190734863 1.0381599664688108 1.1203800439834597 -0.89792400598526 -1.0328400135040283 37.74060336954562 35.0 0.0 no 5929 chrX_93629 18267 high_effect YJL176C 882 - TGCGGTATCTCAAAAGTTTC silent|CCG>CCC|P|300 silent|CCG>CCA|P|300 SWI3 SWItching deficient 825.0 0 0 0 0 -0.12216782107749692 P32591 43.09980292085129 40.0 0.0 no 5930 chrX_93673 18268 high_effect YJL176C 838 - TTTCTTTGGATTGGCACTTT K|285|N silent|AAG>AAA|K|285 SWI3 SWItching deficient 825.0 0 0 0 0 -0.5305464102199068 P32591 0.4318645596504211 47.18348076568475 35.0 0.0 no 5931 chrX_93868 18273 high_effect YJL176C 643 - ACTCTTTGTGTCTCCAAAAA K|220|N silent|AAG>AAA|K|220 S|221|T S|221|N SWI3 SWItching deficient 825.0 0 0 0 0 -0.9322343818431984 P32591 0.4589547514915466 0.5853338241577148 0.5097233653068542 42.747953999845436 35.0 0.0 no 5932 chrX_93995 18277 high_effect YJL176C 516 - TCAATAACAGTGTTATTCTC E|179|Q E|179|K SWI3 SWItching deficient 825.0 0 1 0 0 0.2326864475192698 P32591 0.10957828164100647 0.309166818857193 38.23783929340186 30.0 0.0 no 5933 chrX_94197 18283 high_effect YJL176C 314 - TATCACTATCCTCATTATCT D|111|H D|111|N S|110|T S|110|N SWI3 SWItching deficient 825.0 0 0 0 0 0.2057606100172937 P32591 0.08159016072750093 0.2884058356285095 0.2607077658176422 0.6645339131355286 44.09688254421332 30.0 0.0 no 5934 chrX_94212 18285 high_effect YJL176C 299 - TATCTTGGCCAAAGACGTTC D|106|H D|106|N SWI3 SWItching deficient 825.0 0 0 0 0 -0.05774142007832195 P32591 0.12947380542755127 0.4982286989688873 46.54268918619505 45.0 0.0 no 5935 chrX_94274 18290 high_effect YJL176C 237 - AGCTTATTCGCTTGCATAGT K|85|N silent|AAG>AAA|K|85 SWI3 SWItching deficient 825.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.20315101292002494 P32591 0.5703424215316772 49.89216571430541 40.0 0.0 no 5936 chrX_95111r 18299 essential YJL174W 22 - AAACACCAAAGCACATATGA silent|GTG>GTC|V|13 silent|GTG>GTA|V|13 V|13|L V|13|M KRE9 Killer toxin REsistant 276.0 0 0 0 0 1.1719380051654311 P39005 1.0 0.214718833565712 38.6829176305439 35.0 1.0 no 5937 chrX_95214 18303 essential YJL174W 122 + CTCTGTTCCCGTTGAATGGA S|42|C S|42|F KRE9 Killer toxin REsistant 276.0 0 0 0 0 0.3883215130234666 P39005 0.02475181594491005 0.024333367124199867 52.388380702565364 50.0 1.0 no 5938 chrX_95221r 18304 essential YJL174W 132 - CCATTATCCATCCATTCAAC G|51|R G|51|R KRE9 Killer toxin REsistant 276.0 0 0 0 0 -0.3933415385798504 P39005 0.525718629360199 0.525718629360199 47.697765858540144 40.0 1.0 no 5939 chrX_95222r 18306 essential YJL174W 133 - CCCATTATCCATCCATTCAA G|51|R G|51|R G|51|A G|51|E KRE9 Killer toxin REsistant 276.0 0 0 0 0 0.4184704196136985 P39005 0.525718629360199 0.525718629360199 0.7438397407531738 1.0 50.82727187284184 40.0 1.0 no 5940 chrX_95275 18307 essential YJL174W 183 + TTCACGTTCAGTCTTTGTAC F|62|L silent|TTC>TTT|F|62 T|63|R T|63|M KRE9 Killer toxin REsistant 276.0 0 0 0 0 -2.5623456448361157 P39005 0.5420411229133606 0.031147228553891182 0.01023726724088192 47.07874928230956 40.0 1.0 yes 5941 chrX_95347r 18309 essential YJL174W 258 - TCATCTTGTGTTAGCTCACT D|93|H D|93|N D|92|H D|92|N KRE9 Killer toxin REsistant 276.0 0 0 0 0 -0.6741113461243813 P39005 0.12017635256052014 0.5114781260490417 0.10081467777490616 0.6726651191711426 49.994629718637846 40.0 1.0 no 5942 chrX_95626r 18316 essential YJL174W 537 - GTACCAGTCTGCTTGGTGTA G|185|A G|185|D G|185|R G|185|S KRE9 Killer toxin REsistant 276.0 0 0 0 0 0.002666657527488292 P39005 0.13874998688697815 0.11857730150222777 0.041312847286462784 0.11672347784042357 55.89717882188189 50.0 1.0 no 5943 chrX_96314r 18322 essential YJL173C 193 + AAACATTTGAGATCGACTCG T|66|R T|66|I RFA3 Replication Factor A 122.0 0 0 0 0 0.5560364240160424 P26755 0.9476869702339172 0.9472420215606691 39.3249044387598 40.0 0.0 no 5944 chrX_105061r 18329 essential YJL167W 50 - TCAATTCCTCTACTAATTTA L|23|F silent|TTG>TTA|L|23 E|22|Q E|22|K ERG20 ERGosterol biosynthesis 352.0 0 0 0 0 -1.1430771080284905 P08524 0.02164829708635807 0.1149190440773964 0.10380148142576218 39.32262035993875 25.0 1.0 no 5945 chrX_105062r 18330 essential YJL167W 51 - TTCAATTCCTCTACTAATTT L|23|F silent|TTG>TTA|L|23 ERG20 ERGosterol biosynthesis 352.0 0 0 0 0 -0.1933472283502195 P08524 0.02164829708635807 40.12146141934738 25.0 1.0 no 5946 chrX_105214 18335 essential YJL167W 200 + CAACAAGACCGTTGAACAAT N|68|K silent|AAC>AAT|N|68 ERG20 ERGosterol biosynthesis 352.0 0 0 0 0 1.7236383073733401 P08524 0.2547927498817444 39.50768152386223 40.0 1.0 no 5947 chrX_105216 18337 essential YJL167W 202 + ACAAGACCGTTGAACAATTG N|68|K silent|AAC>AAT|N|68 T|70|S T|70|I ERG20 ERGosterol biosynthesis 352.0 0 0 0 0 0.29744932918283024 P08524 0.2547927498817444 0.7708869576454163 0.14480790495872498 39.776191280434375 40.0 1.0 no 5948 chrX_105261r 18340 essential YJL167W 250 - CTCAATGCACCAACCTAGAA E|90|Q E|90|K ERG20 ERGosterol biosynthesis 352.0 0 0 0 0 -0.9753736583703324 P08524 0.0 0.0 46.026881206084965 45.0 1.0 no 5949 chrX_105336 18342 essential YJL167W 322 + CCAGAAGAGGCCAACCATGT silent|ACC>ACG|T|108 silent|ACC>ACT|T|108 ERG20 ERGosterol biosynthesis 352.0 0 0 0 0 1.159175612712762 P08524 52.702297579604426 55.00000000000001 1.0 no 5950 chrX_105309r 18343 essential YJL167W 298 - GGACTTGTCCATCATATCAT K|105|N silent|AAG>AAA|K|105 ERG20 ERGosterol biosynthesis 352.0 0 1 0 0 1.1908353390107516 P08524 0.5021784901618958 48.180539014905605 40.0 1.0 no 5951 chrX_105350r 18346 essential YJL167W 339 - TCAGGAACCTTGTACCAACA E|120|Q E|120|K ERG20 ERGosterol biosynthesis 352.0 0 0 0 0 0.02562873322647985 P08524 0.2391049712896347 0.3687198460102081 47.6937962085641 45.0 1.0 no 5952 chrX_105491 18348 essential YJL167W 477 + GTCACCTTCCAAACCGAATT silent|GTC>GTG|V|160 silent|GTC>GTT|V|160 T|161|S T|161|I ERG20 ERGosterol biosynthesis 352.0 0 0 0 0 0.6114833748958411 P08524 0.553024411201477 0.13462497293949127 48.52814071737021 45.0 1.0 no 5953 chrX_105539r 18350 essential YJL167W 528 - CTCAAGTCGACTTTGTCTTC L|182|F silent|TTG>TTA|L|182 ERG20 ERGosterol biosynthesis 352.0 0 1 0 0 0.1354200239411602 P08524 0.2385495901107788 3.0218400955200195 47.3489631901702 45.0 1.0 no 5954 chrX_105619 18352 essential YJL167W 605 + TTTCTACTTGCCTGTCGCAT F|203|L silent|TTC>TTT|F|203 Y|204|* silent|TAC>TAT|Y|204 ERG20 ERGosterol biosynthesis 352.0 0 0 0 0 0.8974903954272636 P08524 0.0 53.70065083169293 45.0 1.0 no 5955 chrX_105758r 18356 essential YJL167W 747 - CCGATCTTACCGATCTGTTC G|256|R G|256|S K|254|N silent|AAG>AAA|K|254 ERG20 ERGosterol biosynthesis 352.0 0 0 0 0 -1.3709142137996475 P08524 0.0 0.0 0.0 1.7348999977111816 51.07403153485985 50.0 1.0 no 5956 chrX_127540 18361 essential YJL156C 1393 - CTTCTCAGATAATACAACGT E|470|D silent|GAG>GAA|E|470 E|470|Q E|470|K SSY5 Sulfonylurea Sensitive on YPD 699.0 0 1 0 0 0.287402904318363 P47002 0.10029668360948564 0.05176898837089538 0.05033805221319199 39.64433420466338 35.0 0.0 no 5957 chrX_127983r 18371 essential YJL156C 947 + TTCTTCAATAATCTCTGACC S|317|C S|317|F S|318|* S|318|L SSY5 Sulfonylurea Sensitive on YPD 699.0 0 0 0 0 -1.2380973693305601 P47002 0.025389928370714188 0.022310884669423103 0.03937717527151108 42.32326955772203 35.0 0.0 no 5958 chrX_128046r 18373 essential YJL156C 884 + CCATTGCAACTTACCAAGTA H|296|D H|296|Y C|297|W silent|TGC>TGT|C|297 SSY5 Sulfonylurea Sensitive on YPD 699.0 0 0 0 0 0.12918954787645875 P47002 0.5547215938568115 0.026262788102030758 0.018834764137864116 46.07514912602403 40.0 0.0 no 5959 chrX_128118 18378 essential YJL156C 815 - TCAAATCGTCATCCGTAATA L|278|F silent|TTG>TTA|L|278 D|277|H D|277|N SSY5 Sulfonylurea Sensitive on YPD 699.0 0 0 0 0 0.492521611374442 P47002 0.15469180047512054 0.09344512224197388 0.7466978430747986 41.68908842574013 35.0 0.0 no 5960 chrX_128723r 18390 essential YJL156C 207 + TCGTCATCCATATTTTCTAG S|70|W S|70|L S|71|* S|71|L SSY5 Sulfonylurea Sensitive on YPD 699.0 0 1 0 0 -0.1989677266381424 P47002 0.021016806364059448 0.13265568017959595 0.0066477763466537 44.94531855011064 35.0 0.0 no 5961 chrX_131887 18394 exception YJL154C 2029 - AGACTCTTCAAATATTGTGA E|682|D silent|GAG>GAA|E|682 E|682|Q E|682|K VPS35 Vacuolar Protein Sorting 944.0 0 0 0 0 0.31998318247206503 P34110 0.2394049316644669 0.1039051115512848 0.021562485024333 38.42689223910628 30.0 0.0 no 5962 chrX_132063 18395 exception YJL154C 1853 - GCTTTAAAAGATTGGAATAA K|624|N silent|AAG>AAA|K|624 VPS35 Vacuolar Protein Sorting 944.0 0 0 0 0 0.4424020370162871 P34110 0.2205219715833664 32.776155128613375 25.0 0.0 no 5963 chrX_132160r 18396 exception YJL154C 1753 + CAGCAATAATCACAAATTTT A|586|G A|586|V VPS35 Vacuolar Protein Sorting 944.0 0 0 0 0 0.9813619707920695 P34110 0.061190322041511536 0.2834523916244507 34.609297727557696 25.0 0.0 no 5964 chrX_132330 18397 exception YJL154C 1586 - GTGCCAACTTTTCCTGTATT A|535|P A|535|T L|534|F silent|TTG>TTA|L|534 VPS35 Vacuolar Protein Sorting 944.0 0 0 0 0 0.2143279815317312 P34110 0.015501389279961588 0.014947961084544659 0.01984752155840397 51.052452773777866 40.0 0.0 no 5965 chrX_132397 18399 exception YJL154C 1519 - TTCGTCTACATTTGTATCCG E|513|Q E|513|K D|512|H D|512|N VPS35 Vacuolar Protein Sorting 944.0 0 0 0 0 0.003678997714830129 P34110 0.25018906593322754 0.14734791219234467 0.5242555737495422 0.7224129438400269 46.7610946808 40.0 0.0 no 5966 chrX_132526r 18402 exception YJL154C 1387 + AATCGAAACTGCATCCTCCA S|464|W S|464|L VPS35 Vacuolar Protein Sorting 944.0 0 0 0 0 -0.5136095236831585 P34110 47.76014884314607 45.0 0.0 no 5967 chrX_132663r 18405 exception YJL154C 1250 + TCAATTAATCTCCCAGTGCC Q|418|E Q|418|* VPS35 Vacuolar Protein Sorting 944.0 0 0 0 0 -0.243268805529208 P34110 1.0 50.92115689700574 45.0 0.0 no 5968 chrX_132863 18409 exception YJL154C 1053 - TTCAAATTATCAAAATTATT L|357|F silent|TTG>TTA|L|357 VPS35 Vacuolar Protein Sorting 944.0 0 0 0 0 -0.31881330061805474 P34110 0.037866029888391495 27.710165435901107 10.0 0.0 no 5969 chrX_132905 18410 exception YJL154C 1011 - ACAATCACACTCTCAACTAG V|344|L V|344|I silent|GTG>GTC|V|342 silent|GTG>GTA|V|342 VPS35 Vacuolar Protein Sorting 944.0 0 0 0 0 -0.1621744192867256 P34110 0.15734241902828214 0.0971793681383133 41.15518629379193 40.0 0.0 no 5970 chrX_133009 18413 exception YJL154C 907 - ATCTAAATAAGCATTCGTGG D|309|H D|309|N VPS35 Vacuolar Protein Sorting 944.0 0 0 0 0 0.3774531796818117 P34110 0.12945251166820526 0.6971016526222229 39.043309320782036 35.0 0.0 no 5971 chrX_133086r 18414 exception YJL154C 827 + AAACAAGATTGTTCTCACTT N|277|K silent|AAC>AAT|N|277 VPS35 Vacuolar Protein Sorting 944.0 0 0 0 0 -0.7398882447532684 P34110 1.0 38.42448727777287 30.0 0.0 no 5972 chrX_133348 18417 exception YJL154C 568 - CTCTTTTCTTTCACGTGTTC E|196|Q E|196|K VPS35 Vacuolar Protein Sorting 944.0 0 0 0 0 -0.2618849741980232 P34110 0.0 0.0 48.55970250707254 40.0 0.0 no 5973 chrX_133581r 18421 exception YJL154C 332 + TTTCAATGAAGCGCCCAAGA F|112|L silent|TTC>TTT|F|112 VPS35 Vacuolar Protein Sorting 944.0 0 0 0 0 -0.001095520625255364 P34110 0.4739329218864441 47.251177579195605 45.0 0.0 no 5974 chrX_133801 18426 exception YJL154C 115 - TCTCAATTCGGTCAACATTA L|44|F silent|TTG>TTA|L|44 R|45|T R|45|K VPS35 Vacuolar Protein Sorting 944.0 0 0 0 0 -0.9249455142285296 P34110 0.0 0.0 0.0 42.46304986384672 35.0 0.0 no 5975 chrX_147137 18430 essential YJL143W 36 + GTCATACTAAATGATTTCGG silent|GTC>GTG|V|13 silent|GTC>GTT|V|13 L|15|V silent|CTA>TTA|L|15 0 0 0 0 0.7776879465061257 P39515 0.91568785905838 38.70779599952459 35.0 1.0 no 5976 chrX_147177r 18433 essential YJL143W 79 - ATGCCAAACAACACCACCAA W|32|C W|32|* W|32|S W|32|* 0 0 0 0 -1.1098432667950895 P39515 0.0017151304055005312 0.002334983553737402 46.35235706845509 45.0 1.0 no 5977 chrX_147224r 18434 essential YJL143W 126 - CCTGAACCACGCTCACCTAA G|49|R G|49|R G|47|A G|47|D 0 0 0 0 -0.8514711540137407 P39515 0.002058389596641064 0.002058389596641064 0.110184445977211 0.04160063341259957 52.65661353800789 55.00000000000001 1.0 no 5978 chrX_147275r 18438 essential YJL143W 177 - CCAAAATTACCACCCAGTAC G|66|R G|66|S 0 0 0 0 -1.6375676408629962 P39515 0.0022041399497538805 0.07594657689332962 46.77745991573028 45.0 1.0 no 5979 chrX_147276r 18439 essential YJL143W 178 - ACCAAAATTACCACCCAGTA G|66|R G|66|S G|66|A G|66|D 0 0 0 0 -3.4230745581077846 P39515 0.0022041399497538805 0.07594657689332962 1.0 0.002487714402377605 46.77745991573022 40.0 1.0 yes 5980 chrX_147362 18442 essential YJL143W 261 + CCATGGAATGCTATCATTGC P|88|R P|88|L 0 0 0 0 0.19252234531327853 P39515 0.00402074260637164 0.003675309242680669 47.48266420557252 45.0 1.0 no 5981 chrX_147374 18444 essential YJL143W 273 + ATCATTGCAGGGTTTTTCAC I|92|M silent|ATC>ATT|I|92 0 0 0 0 0.414593904380524 P39515 0.0 48.14723597170071 40.0 1.0 no 5982 chrX_147446 18448 essential YJL143W 345 + ATCACGTGTGCTTGTTTGTT I|116|M silent|ATC>ATT|I|116 T|117|R T|117|M 0 0 0 0 -0.06889848701836379 P39515 0.2166452258825302 0.02413336932659149 0.3556009829044342 50.123604561392476 40.0 1.0 no 5983 chrX_150980r 18449 high_effect YJL140W 22 - TCTTCTCCGTCTTGTTTGAA R|14|T R|14|K R|13|T R|13|K RPB4 RNA Polymerase B 221.0 0 0 0 0 0.43929212557858704 P20433 0.21613183617591855 0.9703323245048524 0.035476673394441605 0.29857441782951355 -0.0997999981045723 -0.1446000039577484 0.31700000166893005 -0.02580000087618828 49.66543137074722 40.0 1.0 no 5984 chrX_150974 18450 high_effect YJL140W 13 + CATCAACCTTTCAAACAAGA S|6|* S|6|L T|7|S T|7|I RPB4 RNA Polymerase B 221.0 0 1 0 0 -1.0401180988313607 P20433 0.005279984325170517 0.1961318701505661 0.025606920942664143 -1.7574000358581543 -1.0959999561309814 39.20127211969668 35.0 1.0 no 5985 chrX_151113r 18455 high_effect YJL140W 155 - TTACTAACCTGGCTTCACTT V|58|L V|58|I RPB4 RNA Polymerase B 221.0 0 0 0 0 -0.1946006747860769 P20433 1.0 0.662643551826477 -1.0178459882736206 -0.6640200018882751 -0.6959999799728394 -0.6657999753952026 -0.9473800063133241 -1.151479959487915 48.184317614070046 40.0 1.0 no 5986 chrX_151124r 18456 high_effect YJL140W 166 - AGCTTCTTTGATTACTAACC A|62|P A|62|T E|61|Q E|61|K RPB4 RNA Polymerase B 221.0 0 0 0 0 -1.6518261330030903 P20433 0.024209585040807724 0.21781206130981445 0.38269364833831787 0.5236726999282837 3.0749316215515137 1.8144999742507932 -0.06347200274467467 -0.21509599685668945 1.8819999694824217 1.6684000492095947 3.719340085983277 1.7483199834823608 43.720294558042326 35.0 1.0 no 5987 chrX_151215 18457 high_effect YJL140W 254 + AAACGCCAATGATGAAACTA N|86|K silent|AAC>AAT|N|86 A|87|G A|87|V RPB4 RNA Polymerase B 221.0 0 0 0 0 0.7386981455606051 P20433 0.15541553497314453 0.3972313404083252 0.2858589291572571 -1.7649999856948853 1.939200043678284 37.523989145780256 35.0 1.0 no 5988 chrX_151220r 18458 high_effect YJL140W 262 - TACTGCCGTAGTTTCATCAT V|94|L V|94|I A|93|P A|93|T RPB4 RNA Polymerase B 221.0 0 1 0 0 0.12842183494231432 P20433 0.30151459574699396 0.1869478523731232 0.2678622901439667 0.5522551536560059 -0.09179999679327012 -0.1607999950647354 -0.4634000062942505 0.21480000019073486 49.4602236100169 40.0 1.0 no 5989 chrX_151450 18463 high_effect YJL140W 489 + ATACAGCTTCTGAAAAGCAC Q|165|E Q|165|* L|166|V L|166|F RPB4 RNA Polymerase B 221.0 0 0 0 0 -1.0499245432564095 P20433 0.1611090898513794 0.022185279056429863 0.01711643673479557 0.3905900120735169 2.0039300918579097 1.728461980819702 1.3365999460220337 0.5005999803543091 41.225900781002785 40.0 1.0 no 5990 chrX_185849r 18465 essential YJL125C 808 + CACTCAATGATGCCCTGGAA L|271|V L|271|F silent|CTC>CTG|L|271 silent|CTC>CTT|L|271 GCD14 General Control Nonderepressible 383.0 0 0 0 0 0.6710589430047493 P46959 1.0 0.0408276803791523 49.610149176546145 50.0 0.0 no 5991 chrX_186120r 18468 essential YJL125C 537 + GACACTACATCTTACGAATT D|180|E silent|GAC>GAT|D|180 T|181|S T|181|I GCD14 General Control Nonderepressible 383.0 0 0 0 0 -0.12907636826337127 P46959 40.00514788441808 35.0 0.0 no 5992 chrX_186178r 18472 essential YJL125C 479 + TAACGTTACGATTACACATC N|161|K silent|AAC>AAT|N|161 GCD14 General Control Nonderepressible 383.0 0 0 0 0 0.05440258340605039 P46959 0.08832534402608871 38.57855761269445 35.0 0.0 no 5993 chrX_186331 18477 essential YJL125C 329 - CCTCGATCACTCTGCTGTGA E|116|Q E|116|K E|116|D silent|GAG>GAA|E|116 GCD14 General Control Nonderepressible 383.0 0 0 0 0 -0.2292019024737387 P46959 0.0 0.0 0.0 54.99996752701208 55.00000000000001 0.0 no 5994 chrX_186359 18479 essential YJL125C 301 - ATTCAACCTTTGCATGATGT L|106|F silent|TTG>TTA|L|106 R|105|S silent|AGG>AGA|R|105 GCD14 General Control Nonderepressible 383.0 0 0 0 0 0.1260683497485224 P46959 0.02365570142865181 0.046945866197347634 45.551994910043156 35.0 0.0 no 5995 chrX_186365r 18480 essential YJL125C 292 + ACTCTTCCTACATCATGCAA S|99|C S|99|F D|98|E silent|GAC>GAT|D|98 GCD14 General Control Nonderepressible 383.0 0 0 0 0 -1.211910590170982 P46959 0.1211707666516304 0.8718375563621521 0.0 48.16240215733404 40.0 0.0 no 5996 chrX_186431r 18483 essential YJL125C 226 + TGCAACCAACTCCTGAATTG Q|77|E Q|77|* P|78|A P|78|S GCD14 General Control Nonderepressible 383.0 0 0 0 0 -1.4701362570167311 P46959 0.3766803741455078 0.0 0.0 45.50111533799964 45.0 0.0 no 5997 chrX_186554 18485 essential YJL125C 106 - ACGAGTATTGAATACCTCTT R|42|P R|42|H GCD14 General Control Nonderepressible 383.0 0 0 0 0 -0.1921771343726284 P46959 0.00936837587505579 0.010552593506872654 42.747559151651615 35.0 0.0 no 5998 chrX_186613r 18487 essential YJL125C 44 + AGGCGATTTAACTCTAATAT silent|GGC>GGG|G|16 silent|GGC>GGT|G|16 GCD14 General Control Nonderepressible 383.0 0 0 0 0 -0.3360284955993209 P46959 38.89998838359953 30.0 0.0 no 5999 chrX_186633r 18488 essential YJL125C 24 + TACAAAGACCTCATCAAGGA Y|9|* silent|TAC>TAT|Y|9 GCD14 General Control Nonderepressible 383.0 0 0 0 0 -1.8011618640374798 P46959 41.665528287817786 40.0 0.0 no 6000 chrX_207925 18492 essential YJL111W 48 + ACAGACGCATCTCAAGGTAA T|17|R T|17|I D|18|E silent|GAC>GAT|D|18 CCT7 Chaperonin Containing TCP-1 550.0 0 0 0 0 -0.9351869619444284 P42943 0.9476869702339172 0.9472420215606691 0.9532920122146606 0.004268762189894915 0.18550997972488406 0.13098886609077454 1.0789999961853027 -0.17679999768733978 -0.311599999666214 2.589400053024292 -0.8668000102043152 45.35999173314303 45.0 1.0 no 6001 chrX_207997 18493 essential YJL111W 120 + AAACCAACTTTAGGTCCCTT P|42|A P|42|S P|42|R P|42|L CCT7 Chaperonin Containing TCP-1 550.0 0 0 0 0 0.3146535075173119 P42943 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.10442371666431427 0.4416323900222778 0.007591426372528076 0.007876843214035034 1.9185999631881716 2.558000087738037 0.7721999883651733 1.6751999855041504 48.00569330436741 40.0 1.0 no 6002 chrX_208000r 18494 essential YJL111W 126 - GAACCTAAGGGACCTAAAGT G|48|A G|48|D G|48|R G|48|S CCT7 Chaperonin Containing TCP-1 550.0 0 0 0 0 -4.626701661357778 P42943 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.019152767956256863 0.0043792687356472015 0.0018335016211494806 0.07929925620555878 4.86959981918335 12.455400466918945 14.095000267028807 8.411600112915039 44.14627763677697 45.0 1.0 yes 6003 chrX_208083r 18496 essential YJL111W 209 - GTACTACATCTAATAATTTT V|76|L V|76|I V|75|L V|75|I CCT7 Chaperonin Containing TCP-1 550.0 0 1 0 0 0.29195585817057923 P42943 0.9539830088615416 0.9574310183525084 0.9539830088615416 0.9574310183525084 0.2777751088142395 0.2050417959690094 0.14256955683231354 1.0 -0.2442000061273575 0.2752000093460083 -1.187800049781799 -1.5582000017166138 34.08557493696253 20.0 1.0 no 6004 chrX_208210 18499 essential YJL111W 333 + GCCAAGCCCTTTTTGGAAGA silent|GCC>GCG|A|112 silent|GCC>GCT|A|112 A|112|G A|112|V CCT7 Chaperonin Containing TCP-1 550.0 0 0 0 0 1.6583292996117365 P42943 0.9484469890594482 0.9504740238189696 0.014104077592492104 1.0 1.2699999809265137 1.0434000492095947 53.60929922131919 50.0 1.0 no 6005 chrX_208236 18501 essential YJL111W 359 + TTCATCTCATTTGATTATGA S|121|* S|121|L S|122|C S|122|F CCT7 Chaperonin Containing TCP-1 550.0 0 0 0 0 -0.2193175006992729 P42943 0.9298099875450134 0.945252001285553 0.9294660091400146 0.33671364188194275 0.12043759971857072 0.0563814751803875 0.08380000293254852 1.0268000364303589 0.929199993610382 -0.7549999952316284 -0.1615999937057495 3.3136000633239746 39.26987269774065 25.0 1.0 no 6006 chrX_208440r 18502 essential YJL111W 566 - CATCCAAATCGTTTCTATCA D|195|H D|195|N L|194|F silent|TTG>TTA|L|194 CCT7 Chaperonin Containing TCP-1 550.0 0 0 0 0 0.2125384044295769 P42943 0.9486550092697144 0.956179976463318 0.9587849974632264 0.053688257932662964 0.6911152005195618 0.12616826593875885 1.0734000205993652 0.520799994468689 1.1751999855041504 -1.8272000551223757 -0.746999979019165 -0.19480000436306 43.46637706140223 35.0 1.0 no 6007 chrX_208591r 18504 essential YJL111W 717 - ACATTCAAACTTAAAATTTT V|246|L V|246|I L|244|F silent|TTG>TTA|L|244 CCT7 Chaperonin Containing TCP-1 550.0 0 0 0 0 -0.3181092129540878 P42943 0.9539830088615416 0.9574310183525084 0.9587849974632264 0.11421643942594527 0.737382173538208 0.012267936952412128 -0.09239999949932097 -0.3882000148296356 0.5604000091552734 -1.2807999849319458 -0.25279998779296875 30.14809932563452 15.0 1.0 no 6008 chrX_208846 18508 essential YJL111W 969 + AATCGTGTCATCCAAGCTGT R|325|G R|325|C CCT7 Chaperonin Containing TCP-1 550.0 0 0 0 0 1.0673862755255854 P42943 0.8994590044021606 0.8926740288734436 0.0032002031803131104 0.0003926122153643519 0.8628000020980835 0.9538000226020812 49.93001648043242 45.0 1.0 no 6009 chrX_214122r 18521 essential YJL109C 3165 + GCTTTAGTCAACTTTAAAAT A|1056|G A|1056|V UTP10 U Three Protein 1769.0 0 0 0 0 0.6472233067832582 P42945 0.9484469890594482 0.9504740238189696 0.627967119216919 0.5071928501129149 35.94856440448143 25.0 0.0 no 6010 chrX_214310 18527 essential YJL109C 2980 - TCCTTTGCTATTCTTGATCA G|1000|R G|1000|R G|1000|A G|1000|E UTP10 U Three Protein 1769.0 0 0 0 0 0.23908891012709554 P42945 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.08749189972877502 0.08749189972877502 0.13095155358314514 0.17708991467952728 48.31242995016294 35.0 0.0 no 6011 chrX_214381 18528 essential YJL109C 2909 - CATCATCTTGACGAATACTA D|976|H D|976|N D|975|H D|975|N UTP10 U Three Protein 1769.0 0 0 0 0 0.31196400476873065 P42945 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.0 0.0 0.0 0.0 39.818588885897896 35.0 0.0 no 6012 chrX_214382 18529 essential YJL109C 2908 - ATCATCTTGACGAATACTAT D|976|H D|976|N D|975|H D|975|N UTP10 U Three Protein 1769.0 0 0 0 0 0.9342522062052856 P42945 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.0 0.0 0.0 0.0 38.503443016074975 30.0 0.0 no 6013 chrX_214473r 18532 essential YJL109C 2814 + AACAAACTATTACTTGTAAT N|939|K silent|AAC>AAT|N|939 L|941|V silent|CTA>TTA|L|941 UTP10 U Three Protein 1769.0 0 0 0 0 -1.4283676277509063 P42945 0.9439849853515624 0.9512209892272948 0.0 0.040441520512104034 31.752227647181314 20.0 0.0 no 6014 chrX_214546r 18534 essential YJL109C 2741 + TACAGAACTAACCAACGTAA T|915|R T|915|I UTP10 U Three Protein 1769.0 0 0 0 0 0.16536445009822998 P42945 0.9476869702339172 0.9472420215606691 0.5198078751564026 0.19604352116584775 37.52709819387383 35.0 0.0 no 6015 chrX_214579r 18535 essential YJL109C 2708 + GAACACTATCACATACTTGA N|904|K silent|AAC>AAT|N|904 T|905|S T|905|I UTP10 U Three Protein 1769.0 0 0 0 0 0.2688307902838909 P42945 0.9439849853515624 0.9491789937019348 0.9472420215606691 1.0 0.810696005821228 0.3876597285270691 39.697420503396074 35.0 0.0 no 6016 chrX_215242r 18542 essential YJL109C 2045 + TTCTTATTCCTCCCTATTTG S|683|C S|683|F UTP10 U Three Protein 1769.0 0 0 0 0 0.20697260629265016 P42945 0.945252001285553 0.9294660091400146 0.06778756529092789 0.08688655495643616 49.46003930382386 35.0 0.0 no 6017 chrX_215375 18543 essential YJL109C 1915 - TCTCTTTGGCGTTAAAATTC K|644|N silent|AAG>AAA|K|644 R|645|T R|645|K UTP10 U Three Protein 1769.0 0 0 0 0 0.608552465940454 P42945 0.9355990290641784 0.932735025882721 0.955805003643036 0.04066912829875946 0.039042890071868896 1.0 41.590508059616134 35.0 0.0 no 6018 chrX_215298 18546 essential YJL109C 1992 - AACAACACTGTCTTGGCATA L|670|F silent|TTG>TTA|L|670 silent|GTG>GTC|V|669 silent|GTG>GTA|V|669 UTP10 U Three Protein 1769.0 0 0 0 0 0.4262445622202887 P42945 0.9587849974632264 0.2361564636230469 44.35341320886108 40.0 0.0 no 6019 chrX_215441 18547 essential YJL109C 1849 - TAACCATGCCTCACTATCTT W|622|C W|622|* W|622|S W|622|* UTP10 U Three Protein 1769.0 0 0 0 0 0.195602997625088 P42945 0.8858469724655151 0.8858469724655151 0.04095562919974327 0.07519091665744781 49.04786964676635 40.0 0.0 no 6020 chrX_215507 18548 essential YJL109C 1783 - AGACAAAAAGTAGTGCTTAG L|600|F silent|TTG>TTA|L|600 UTP10 U Three Protein 1769.0 0 0 0 0 0.8621330629230529 P42945 0.9587849974632264 0.1016167774796486 36.17333762404678 35.0 0.0 no 6021 chrX_215843 18551 essential YJL109C 1447 - TTCTCCAGTTTCTGTTAGCA E|489|Q E|489|K G|488|A G|488|E UTP10 U Three Protein 1769.0 0 0 0 0 -0.1790163047918782 P42945 0.956179976463318 0.9475290179252625 0.9499930143356324 0.9438679814338684 0.5453425645828247 0.8130639791488647 0.7862727642059326 1.0 52.417839963089705 40.0 0.0 no 6022 chrX_215928 18552 essential YJL109C 1362 - TCCTTTTTAGTAGTTTCCAC K|460|N silent|AAG>AAA|K|460 D|461|H D|461|N UTP10 U Three Protein 1769.0 0 0 0 0 -0.16094653005911186 P42945 0.9355990290641784 0.9486550092697144 0.956179976463318 0.3096828758716583 0.07921487838029861 0.2507223784923553 48.40534034545335 35.0 0.0 no 6023 chrX_215929 18553 essential YJL109C 1361 - CCTTTTTAGTAGTTTCCACG K|460|N silent|AAG>AAA|K|460 UTP10 U Three Protein 1769.0 0 0 0 0 0.3106495990908043 P42945 0.9355990290641784 0.3096828758716583 48.39683346326797 40.0 0.0 no 6024 chrX_216062 18556 essential YJL109C 1228 - TAACACCAAATCTTCATTTA silent|GTG>GTC|V|415 silent|GTG>GTA|V|415 V|415|L V|415|M UTP10 U Three Protein 1769.0 0 0 0 0 0.09997179166172857 P42945 0.9539830088615416 0.9587630033493042 0.566230833530426 0.12477169930934905 37.2559003582175 25.0 0.0 no 6025 chrX_216116 18557 essential YJL109C 1174 - TGACTTGTCCTCTAAAATTT K|397|N silent|AAG>AAA|K|397 UTP10 U Three Protein 1769.0 0 0 0 0 1.3038674985233294 P42945 0.9355990290641784 0.3402842283248901 40.42601977470128 30.0 0.0 no 6026 chrX_216124r 18559 essential YJL109C 1163 + TTACCTTTCCGAAATTTTAG Y|389|* silent|TAC>TAT|Y|389 L|390|V L|390|F UTP10 U Three Protein 1769.0 0 0 0 0 -0.0535571529152486 P42945 0.9512209892272948 0.9587849974632264 0.4317932426929474 0.2933475971221924 40.39736458043751 30.0 0.0 no 6027 chrX_216239 18561 essential YJL109C 1051 - CCTTGCTATGGATCTTGTAT R|357|T R|357|K A|356|P A|356|T UTP10 U Three Protein 1769.0 0 0 0 0 -0.07344670794083498 P42945 0.932735025882721 0.955805003643036 0.9573720097541808 0.9523990154266356 0.5936726927757263 1.0 0.17282697558403015 0.32306212186813354 48.81203324714926 40.0 0.0 no 6028 chrX_216239r 18562 essential YJL109C 1048 + CCTATACAAGATCCATAGCA silent|TCC>TCG|S|350 silent|TCC>TCT|S|350 T|352|R T|352|I UTP10 U Three Protein 1769.0 0 0 0 0 -0.7237713813703532 P42945 0.9476869702339172 0.9472420215606691 0.03143589198589325 0.7334567308425903 45.85040212644924 40.0 0.0 no 6029 chrX_216556r 18565 essential YJL109C 731 + ACTTTTAGCCTCTAAATCAA L|245|V L|245|F UTP10 U Three Protein 1769.0 0 0 0 0 -0.05234402458302645 P42945 0.9512209892272948 0.9587849974632264 0.04835626482963562 0.162229984998703 41.165722164507656 30.0 0.0 no 6030 chrX_216814 18569 essential YJL109C 476 - TCGACAAACAATTAAACAAA silent|TCG>TCC|S|165 silent|TCG>TCA|S|165 L|164|F silent|TTG>TTA|L|164 UTP10 U Three Protein 1769.0 0 0 0 0 0.533808583604009 P42945 0.9587849974632264 0.1752280294895172 30.098560412727466 25.0 0.0 no 6031 chrX_216950r 18572 essential YJL109C 337 + CTACACTACATGCAACAGAA T|114|R T|114|I L|115|V silent|CTA>TTA|L|115 UTP10 U Three Protein 1769.0 0 0 0 0 0.6275206895727685 P42945 0.9476869702339172 0.9472420215606691 0.9512209892272948 0.038796547800302505 0.0352618545293808 0.21807976067066195 40.872228773167315 40.0 0.0 no 6032 chrX_216983r 18574 essential YJL109C 304 + TGCTATTGGCTTCTTCTAAA L|103|V silent|CTA>TTA|L|103 UTP10 U Three Protein 1769.0 0 0 0 0 1.1214232780142512 P42945 0.9512209892272948 0.34081387519836426 44.79267852457547 35.0 0.0 no 6033 chrX_216997r 18575 essential YJL109C 290 + TATCAATGCTTACTTGCTAT I|98|M silent|ATC>ATT|I|98 UTP10 U Three Protein 1769.0 0 0 0 0 0.711682449133564 P42945 0.9598389863967896 0.0150905791670084 42.0190779013514 30.0 0.0 no 6034 chrX_217108 18576 essential YJL109C 182 - TGGCAAATTTTGGCTCAATT A|67|P A|67|T UTP10 U Three Protein 1769.0 0 0 0 0 0.536343646520401 P42945 0.9573720097541808 0.9523990154266356 0.2565121054649353 0.7065352797508241 43.269623151018784 35.0 0.0 no 6035 chrX_217249r 18577 essential YJL109C 38 + CAACAATGCTACTGTTGCGT N|14|K silent|AAC>AAT|N|14 UTP10 U Three Protein 1769.0 0 0 0 0 0.9476282285186316 P42945 0.9439849853515624 0.9993186593055724 46.51012793874753 45.0 0.0 no 6036 chrX_221564 18585 no_effect YJL106W 174 + TTTCCTTTATCGAACATATT P|60|A P|60|S P|60|R P|60|L 0 0 0 0 -0.18393945536597608 P32581 0.4356244504451752 0.4364137351512909 0.2882295846939087 0.1912933737039566 39.89235722571743 25.0 1.0 no 6037 chrX_221567r 18586 no_effect YJL106W 180 - TTACCCAATATGTTCGATAA G|66|A G|66|D G|66|R G|66|S 0 0 0 0 0.1716463104998882 P32581 0.6935713887214661 0.6148713231086731 0.4875466525554657 0.8802021741867065 40.767300969986884 30.0 1.0 no 6038 chrX_221650 18588 no_effect YJL106W 260 + AACAAAGACACAAGGTGTAG T|88|R T|88|I 0 0 0 0 0.16603648149829686 P32581 0.11450418829917908 0.08896922320127487 37.09557075215844 40.0 1.0 no 6039 chrX_221707r 18591 no_effect YJL106W 320 - CTCTGACCCTCGTATAATCC R|113|T R|113|K V|112|L V|112|I 0 0 0 0 0.2541325389277685 P32581 0.0 0.0 0.032966304570436485 0.17115049064159393 51.66257670945117 50.0 1.0 no 6040 chrX_221815 18594 no_effect YJL106W 425 + ACATATCGTAATGGAATGTA H|143|D H|143|Y I|144|M silent|ATC>ATT|I|144 0 0 0 0 -0.20103865803466425 P32581 0.0 0.0 0.0 37.45760669015135 30.0 1.0 no 6041 chrX_221809r 18595 no_effect YJL106W 422 - ATTCCATTACGATATGTAAT E|147|Q E|147|K M|146|I M|146|I 0 0 0 0 1.0412679198638228 P32581 0.0 0.0 0.0 0.0 38.399421770388756 25.0 1.0 no 6042 chrX_221806 18596 no_effect YJL106W 416 + TTACCAATTACATATCGTAA Y|140|* silent|TAC>TAT|Y|140 Q|141|E Q|141|* 0 0 0 0 -0.5687885216299893 P32581 0.06701093912124634 37.14173895865649 25.0 1.0 no 6043 chrX_222056 18601 no_effect YJL106W 666 + GTCATTAAACTTGCAGATTT silent|GTC>GTG|V|223 silent|GTC>GTT|V|223 0 0 0 0 -0.10314155191890724 P32581 39.95246870989449 30.0 1.0 no 6044 chrX_222088r 18602 no_effect YJL106W 701 - ACGGGTTTTTATTTTCAACA silent|CCG>CCC|P|240 silent|CCG>CCA|P|240 0 0 0 0 0.5251220493144586 P32581 42.06664872288218 30.0 1.0 no 6045 chrX_222117r 18604 no_effect YJL106W 730 - ATACCATCTTGTGGAAACGT W|249|C W|249|* W|249|S W|249|* 0 1 0 0 0.4302540561310328 P32581 0.0 0.0 44.60598884005435 40.0 1.0 no 6046 chrX_222385r 18613 no_effect YJL106W 998 - GCAATTTCAAGTTTAATTTA L|339|F silent|TTG>TTA|L|339 0 0 0 0 0.18316480919112216 P32581 1.0 35.07702187772861 20.0 1.0 no 6047 chrX_222450r 18615 no_effect YJL106W 1063 - CTCAGATAAATCGGATAGTT E|361|Q E|361|K 0 0 0 0 -0.5379206259397484 P32581 0.6224678158760071 0.6968017220497131 39.23913016157599 35.0 1.0 no 6048 chrX_222680r 18622 no_effect YJL106W 1293 - TCATTAGACTCTGTTTCTGC D|438|H D|438|N 0 0 0 0 1.6957497880607542 P32581 0.1194000244140625 0.4902517199516296 47.326044688125364 40.0 1.0 no 6049 chrX_222818 18624 no_effect YJL106W 1428 + GATCACTCAATACCTGATGT H|478|D H|478|Y H|478|Q silent|CAC>CAT|H|478 0 0 0 0 -0.19688965197737912 P32581 0.6362607479095459 0.9682465195655824 0.6833894848823547 45.037837147836676 40.0 1.0 no 6050 chrX_227342 18626 essential YJL104W 15 + TTCATACAGGTTATAATCAC F|6|L silent|TTC>TTT|F|6 Q|8|E Q|8|* 0 0 0 0 0.3000428205069549 P42949 0.9387490153312684 0.9590039849281312 0.389269083738327 0.02174072898924351 38.142937263108756 30.0 1.0 no 6051 chrX_227434 18631 essential YJL104W 107 + TGCTACAAATGCATCTAGAA A|37|G A|37|V T|38|R T|38|I 0 0 0 0 -0.08924083513410266 P42949 0.9484469890594482 0.9504740238189696 0.9476869702339172 0.9472420215606691 0.3442015051841736 0.15029782056808472 0.5313370227813721 0.1888028383255005 40.016520047797655 35.0 1.0 no 6052 chrX_245629r 18638 essential YJL097W 41 - CAGCAGAAAGCAAATTATAA A|20|P A|20|T PHS1 PTPLA Homolog involved in Sphingolipid biosynthesis 1 217.0 0 0 0 0 0.2603263894118745 P40857 0.024887796491384503 0.018219701945781708 34.429954845525856 30.0 1.0 no 6053 chrX_245681 18639 essential YJL097W 90 + ATCTCCTTGTACCCAAAAGT I|31|M silent|ATC>ATT|I|31 S|32|C S|32|F PHS1 PTPLA Homolog involved in Sphingolipid biosynthesis 1 217.0 0 0 0 0 -0.2147558338945814 P40857 0.07138146460056305 0.198757141828537 0.7199382781982422 48.215011077885656 40.0 1.0 no 6054 chrX_245692r 18640 essential YJL097W 104 - ATGCTGGCTGTCCAACTTTT A|41|P A|41|T PHS1 PTPLA Homolog involved in Sphingolipid biosynthesis 1 217.0 0 0 0 0 0.7922860426541344 P40857 0.2725470066070557 0.5367915034294128 52.8601391240324 45.0 1.0 no 6055 chrX_245863r 18645 essential YJL097W 275 - CACTTGTGTTTGGCAACAAT S|98|T S|98|N PHS1 PTPLA Homolog involved in Sphingolipid biosynthesis 1 217.0 0 0 0 0 1.261687562725748 P40857 1.0 0.08915629982948302 44.68706234628934 40.0 1.0 no 6056 chrX_246023 18646 essential YJL097W 432 + TTCTGGATTTTGTACCCCAC F|145|L silent|TTC>TTT|F|145 PHS1 PTPLA Homolog involved in Sphingolipid biosynthesis 1 217.0 0 1 0 0 -0.80756768831645 P40857 0.0 52.34643768976542 45.0 1.0 no 6057 chrX_261586 18654 essential YJL091C 947 - ACAAGTAAAATCCCGTGTTT L|322|F silent|TTG>TTA|L|322 0 0 0 0 0.8697062771822651 P47026 0.9587849974632264 0.035257093608379364 42.570387132939175 35.0 0.0 no 6058 chrX_262009r 18661 essential YJL091C 521 + TAACGGTATTGTTTCTTCTA N|175|K silent|AAC>AAT|N|175 0 0 0 0 0.04321542033372 P47026 0.9439849853515624 0.4232901036739349 41.732913778959066 30.0 0.0 no 6059 chrX_262046 18662 essential YJL091C 487 - TCCTACACCAAGATCCATCA G|169|R G|169|R G|169|A G|169|E 0 0 0 0 -6.9514646757902385 P47026 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.0 0.0 0.0 0.0 50.63860484156443 45.0 0.0 yes 6060 chrX_262060r 18663 essential YJL091C 470 + AACTTGGGGGACATCCCTGA T|158|S T|158|I 0 0 0 0 -0.034833482425097616 P47026 0.9491789937019348 0.9472420215606691 0.0 0.0 54.07867144932493 55.00000000000001 0.0 no 6061 chrX_262161r 18670 essential YJL091C 369 + CCGTATATTACTGCGTATCG P|124|R P|124|L 0 0 0 0 0.21797502068971386 P47026 0.9432820081710817 0.9430609941482544 0.09517303109169006 0.0675169825553894 46.591330786766825 45.0 0.0 no 6062 chrX_262379 18672 essential YJL091C 154 - ATCAATTATGTATTGCACGC D|58|H D|58|N 0 0 0 0 0.3926689869035835 P47026 0.9486550092697144 0.956179976463318 0.0 0.0 42.26280118883665 35.0 0.0 no 6063 chrX_263772 18683 essential YJL090C 1260 - AACTCTATTGTGCTGAGGAA E|426|D silent|GAG>GAA|E|426 E|426|Q E|426|K 0 0 0 0 0.3201483042862911 P47027 0.9933249950408936 1.0004899501800537 0.9891330003738404 0.6721294522285461 0.3837432861328125 0.6581385135650635 43.804280796383686 40.0 0.0 no 6064 chrX_264033r 18686 essential YJL090C 996 + ATCATTCATCATATTTTTCC I|333|M silent|ATC>ATT|I|333 H|335|D H|335|Y 0 0 0 0 0.4207707711538429 P47027 1.0027899742126465 0.9917020201683044 0.9918540120124816 0.23296302556991574 0.8577048778533936 0.9818522930145264 41.52795079168681 25.0 0.0 no 6065 chrX_264134r 18687 essential YJL090C 895 + AGACAAATTTTTCAGTACTA T|300|R T|300|I 0 0 0 0 -0.4294559297495865 P47027 0.9773380160331726 0.9893620014190674 0.5793947577476501 0.2241091877222061 36.20536738730039 25.0 0.0 no 6066 chrX_264275r 18694 essential YJL090C 754 + ATGCCCAATCCTCTCTGCAG A|253|G A|253|V silent|GCC>GCG|A|253 silent|GCC>GCT|A|253 0 1 0 0 0.020953930033968338 P47027 0.9919250011444092 0.991150975227356 0.37809765338897705 0.9982590079307556 57.46083375733747 55.00000000000001 0.0 no 6067 chrX_264332r 18695 essential YJL090C 697 + GATCAAACTCTTGCGATTGC S|234|* S|234|L 0 0 0 0 -0.01750696065537405 P47027 0.9753659963607788 0.7192925214767456 44.98602313497816 45.0 0.0 no 6068 chrX_264514r 18698 essential YJL090C 515 + GCAGATATCCATTTTTGTTA Q|173|E Q|173|* 0 0 0 0 -0.011076724347258815 P47027 1.0026899576187134 44.29430079639303 30.0 0.0 no 6069 chrX_264635r 18704 essential YJL090C 394 + CTTCCATCGATTCATTGGTT S|133|C S|133|F silent|TCC>TCG|S|133 silent|TCC>TCT|S|133 0 0 0 0 0.4342926621734531 P47027 0.9879119992256165 0.9685909748077391 0.0576147809624672 0.06671321392059326 48.884279112987315 40.0 0.0 no 6070 chrX_264734 18705 essential YJL090C 298 - TATCTTCAGCATCTCATAGG K|105|N silent|AAG>AAA|K|105 silent|CTG>CTC|L|104 silent|CTG>CTA|L|104 0 0 0 0 -0.245314088475124 P47027 0.9806249737739564 0.5318827033042908 46.18713820199065 40.0 0.0 no 6071 chrX_270648 18711 essential YJL087C 1818 - CCAACTATTTTTCTCACAGT G|613|R G|613|S V|612|L V|612|I TRL1 tRNA Ligase 827.0 0 0 0 0 0.11565796604047995 P09880 0.941340982913971 0.951104998588562 0.9539830088615416 0.9574310183525084 0.603461503982544 0.6832282543182373 0.4246309399604797 0.6050814390182495 45.06531914412403 35.0 0.0 no 6072 chrX_270708 18712 essential YJL087C 1758 - TCATCATCTTTCGGGATCTC E|593|Q E|593|K D|592|H D|592|N TRL1 tRNA Ligase 827.0 0 0 0 0 -2.1861478616013663 P09880 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.5781587958335876 0.9072480201721193 0.08686437457799911 0.3397880792617798 49.43424675321796 45.0 0.0 yes 6073 chrX_270919 18713 essential YJL087C 1547 - ATTCGTCCCATTTAATACTT E|522|Q E|522|K D|521|H D|521|N TRL1 tRNA Ligase 827.0 0 0 0 0 0.8565906001018267 P09880 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.055738605558872216 0.07907965034246445 0.1150163933634758 0.4557777643203736 44.61483895895691 30.0 0.0 no 6074 chrX_270991r 18715 essential YJL087C 1472 + CGCGCCATATGACAAACTAT A|492|G A|492|V P|493|A P|493|S TRL1 tRNA Ligase 827.0 0 0 0 0 -0.2158267585675443 P09880 0.9484469890594482 0.9504740238189696 0.9562489986419678 0.9498909711837769 0.3957465887069702 1.0 0.8032315373420715 0.7583310008049011 45.13033993161394 45.0 0.0 no 6075 chrX_271360 18721 essential YJL087C 1106 - CCAACTCGGCCACTTTTTCG L|375|F silent|TTG>TTA|L|375 E|374|D silent|GAG>GAA|E|374 TRL1 tRNA Ligase 827.0 0 0 0 0 -0.07988894047204333 P09880 0.9587849974632264 0.94931298494339 0.10502729564905168 0.22456762194633484 53.242386333190616 55.00000000000001 0.0 no 6076 chrX_271398r 18726 essential YJL087C 1065 + CTACAATCATATGGCATGAG Q|357|E Q|357|* TRL1 tRNA Ligase 827.0 0 0 0 0 -1.3149259721894575 P09880 0.9590039849281312 1.0 41.14390962864371 40.0 0.0 no 6077 chrX_271452r 18727 essential YJL087C 1011 + ATCTGTGAGAATTACTTGAA I|338|M silent|ATC>ATT|I|338 TRL1 tRNA Ligase 827.0 0 0 0 0 -0.20021937278210286 P09880 0.9598389863967896 0.04849110916256905 37.42200456865089 30.0 0.0 no 6078 chrX_271648 18730 essential YJL087C 818 - GCTTTTCAGTACTCTTCAAG K|279|N silent|AAG>AAA|K|279 E|278|Q E|278|K TRL1 tRNA Ligase 827.0 0 0 0 0 0.6863783229731875 P09880 0.9355990290641784 0.956179976463318 0.9475290179252625 0.5197145938873291 0.4162769615650177 0.5979542136192322 46.1006651587312 40.0 0.0 no 6079 chrX_271700r 18731 essential YJL087C 763 + CTGCAACCGGATCTTTTGAA A|256|G A|256|V T|257|S T|257|I TRL1 tRNA Ligase 827.0 0 0 0 0 -0.3518190827053352 P09880 0.9484469890594482 0.9504740238189696 0.9491789937019348 0.9472420215606691 0.3693799674510956 0.2911774218082428 0.35713157057762146 0.030778994783759117 46.69489741849082 45.0 0.0 no 6080 chrX_272142 18742 essential YJL087C 324 - GCTTTTATAGTGACATCGTA A|115|P A|115|T TRL1 tRNA Ligase 827.0 0 1 0 0 0.6077245371363931 P09880 0.9573720097541808 0.9523990154266356 0.03761110454797745 0.03429952636361122 44.079880597501976 35.0 0.0 no 6081 chrX_272238r 18745 essential YJL087C 225 + AATCCAGTTATTGTTGCTAG P|77|A P|77|S P|77|R P|77|L TRL1 tRNA Ligase 827.0 0 0 0 0 0.1915651038197773 P09880 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.5597460865974426 0.2664857804775238 0.16282449662685394 0.14188092947006226 44.125096226568076 35.0 0.0 no 6082 chrX_272390 18750 essential YJL087C 76 - TCTATAAGCTCTGCCTCTAC R|32|T R|32|K TRL1 tRNA Ligase 827.0 0 0 0 0 0.318912770066672 P09880 0.932735025882721 0.955805003643036 0.02783088758587837 1.0 50.02266154270114 45.0 0.0 no 6083 chrX_273182r 18756 essential YJL085W 358 - TTCTGAGTTTTCTTCTCGAT E|126|Q E|126|K EXO70 EXOcyst 623.0 0 0 0 0 0.6762008698915185 P19658 0.2336173355579376 0.32343509793281555 1.2278000116348269 1.6579999923706057 46.27649374236103 35.0 1.0 no 6084 chrX_273207r 18758 essential YJL085W 383 - CCAAGTGAGTTAAAATCCCA L|134|F silent|TTG>TTA|L|134 EXO70 EXOcyst 623.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.4530967306651376 P19658 0.07936769723892212 3.460400104522705 44.373473295891465 40.0 1.0 no 6085 chrX_273356 18761 essential YJL085W 529 + AGCAGTTAGGCGCTTTATCG Q|178|E Q|178|* EXO70 EXOcyst 623.0 0 0 0 0 -0.982786466356362 P19658 1.0 0.6772000193595886 51.62310340259427 50.0 1.0 no 6086 chrX_273354r 18762 essential YJL085W 530 - ACGATAAAGCGCCTAACTGC silent|TCG>TCC|S|183 silent|TCG>TCA|S|183 EXO70 EXOcyst 623.0 0 0 0 0 0.7991483852940398 P19658 46.3689129304181 50.0 1.0 no 6087 chrX_273402 18763 essential YJL085W 575 + TTCAGAAGGTTCTATTATAC S|193|* S|193|L EXO70 EXOcyst 623.0 0 0 0 0 -1.5275118852806768 P19658 0.04716868326067925 0.11060000211000444 38.250473815004455 30.0 1.0 no 6088 chrX_273515r 18764 essential YJL085W 691 - GCTACTGCCCTTCTCATACG S|237|T S|237|N S|236|T S|236|N EXO70 EXOcyst 623.0 0 0 0 0 0.6531356871001911 P19658 0.07508786022663116 1.0 0.0 0.0 1.0072000026702879 -0.10660000145435332 0.18880000710487368 0.12160000205039978 55.860569991957 55.00000000000001 1.0 no 6089 chrX_273516r 18765 essential YJL085W 692 - CGCTACTGCCCTTCTCATAC S|237|T S|237|N S|236|T S|236|N EXO70 EXOcyst 623.0 0 0 0 0 0.3382049743506407 P19658 0.07508786022663116 1.0 0.0 0.0 1.0072000026702879 -0.10660000145435332 0.18880000710487368 0.12160000205039978 55.86056999195704 55.00000000000001 1.0 no 6090 chrX_273517r 18767 essential YJL085W 693 - CCGCTACTGCCCTTCTCATA S|237|T S|237|N G|238|R G|238|R EXO70 EXOcyst 623.0 0 0 0 0 -3.0152317118990566 P19658 0.07508786022663116 1.0 0.04644085466861725 0.04644085466861725 1.0072000026702879 -0.10660000145435332 6.604400157928468 6.604400157928468 58.91609221956054 55.00000000000001 1.0 yes 6091 chrX_273667 18770 essential YJL085W 840 + AGCGCATATGCTAAGCTTTT S|281|R silent|AGC>AGT|S|281 A|282|G A|282|V EXO70 EXOcyst 623.0 0 0 0 0 -0.6866878564447114 P19658 0.5093168616294861 0.3546750247478485 0.2737960517406464 -0.4560000002384186 0.8277999758720398 0.3355999886989593 48.240890096868725 40.0 1.0 no 6092 chrX_273732 18771 essential YJL085W 905 + ATTCTTTAGTTTTGAGCTAG F|303|L silent|TTC>TTT|F|303 EXO70 EXOcyst 623.0 0 0 0 0 1.0943186345897509 P19658 1.0 0.5184000134468079 41.58525352944008 30.0 1.0 no 6093 chrX_273913r 18772 essential YJL085W 1089 - TCAGTGACACCATTATTGGA E|370|Q E|370|K EXO70 EXOcyst 623.0 0 0 0 0 -2.7158481006942403 P19658 0.1238626390695572 0.13815532624721527 0.6467999815940857 0.9896000027656556 46.258332327535754 40.0 1.0 yes 6094 chrX_273917r 18774 essential YJL085W 1093 - TGCTTCAGTGACACCATTAT A|371|P A|371|T E|370|Q E|370|K EXO70 EXOcyst 623.0 0 0 0 0 -0.6204669973674082 P19658 0.3202708661556244 0.14204417169094086 0.1238626390695572 0.13815532624721527 -2.0634000301361084 1.0296000242233276 0.6467999815940857 0.9896000027656556 48.18219488570338 40.0 1.0 no 6095 chrX_273950r 18775 essential YJL085W 1126 - GAACTTTCTTAGTCTTGACA K|381|N silent|AAG>AAA|K|381 EXO70 EXOcyst 623.0 0 0 0 0 -0.13527473551503874 P19658 0.03447139263153076 0.2608000040054321 42.72391102974882 35.0 1.0 no 6096 chrX_273984 18776 essential YJL085W 1157 + AAACGGATGTTTAGGCGCCA N|387|K silent|AAC>AAT|N|387 EXO70 EXOcyst 623.0 0 0 0 0 -0.4499230314247329 P19658 0.8425596356391907 -0.5594000220298767 49.571362080670845 50.0 1.0 no 6097 chrX_274007 18777 essential YJL085W 1180 + ACAATATCACACGTGAAAAT D|394|E silent|GAC>GAT|D|394 EXO70 EXOcyst 623.0 0 0 0 0 0.1805832568459294 P19658 1.0 0.7279999852180481 35.00933377619373 30.0 1.0 no 6098 chrX_274001r 18783 essential YJL085W 1177 - TTCACGTGTGATATTGTCCA E|399|Q E|399|K R|398|P R|398|H EXO70 EXOcyst 623.0 0 0 0 0 0.0738795126800015 P19658 0.4124213457107544 0.6545796990394592 0.4896831512451172 0.15642954409122467 0.6883999705314636 0.8145999908447266 1.2913999557495115 3.5485999584198 48.139385343024685 40.0 1.0 no 6099 chrX_281294r 18787 no_effect YJL082W 112 - GACAAAATCCATTGCCTTTA V|44|L V|44|I IML2 Increased Minichromosome Loss 731.0 0 0 0 0 0.29587062403893205 P47031 0.9539830088615416 0.9574310183525084 0.2890574038028717 0.09355003386735916 43.39929886969554 35.0 1.0 no 6100 chrX_281606r 18793 no_effect YJL082W 424 - TTCACTAAATAACATCAACA E|148|Q E|148|K S|147|T S|147|N IML2 Increased Minichromosome Loss 731.0 0 0 0 0 -2.083646872565831 P47031 0.956179976463318 0.9475290179252625 0.9512869715690612 0.9536849856376648 0.05547673255205154 0.047474123537540436 0.05485660582780838 0.03250875324010849 33.59142241460109 25.0 1.0 yes 6101 chrX_281645 18794 no_effect YJL082W 460 + CCAAGGCTTTGCTAAAGTTA silent|GCC>GCG|A|154 silent|GCC>GCT|A|154 A|156|G A|156|V IML2 Increased Minichromosome Loss 731.0 0 0 0 0 -0.9135128061795234 P47031 0.9484469890594482 0.9504740238189696 0.0 0.0 45.444728069617845 40.0 1.0 no 6102 chrX_281645r 18795 no_effect YJL082W 463 - CCTTAACTTTAGCAAAGCCT R|161|T R|161|K K|159|N silent|AAG>AAA|K|159 IML2 Increased Minichromosome Loss 731.0 0 0 0 0 0.3721349197149289 P47031 0.932735025882721 0.955805003643036 0.9355990290641784 0.0 0.0 0.010072554461658 46.543647098991975 40.0 1.0 no 6103 chrX_281740r 18797 no_effect YJL082W 558 - TGGCTCTTTTCGCTTGGAGA S|192|T S|192|N K|191|N silent|AAG>AAA|K|191 IML2 Increased Minichromosome Loss 731.0 0 0 0 0 0.0918603369262212 P47031 0.9512869715690612 0.9536849856376648 0.9355990290641784 0.8632286190986633 0.4660906195640564 0.4505079090595245 53.80518672879424 50.0 1.0 no 6104 chrX_281817 18800 no_effect YJL082W 632 + ACCATACAAATTGTCTTCCG P|212|R P|212|L P|212|A P|212|S IML2 Increased Minichromosome Loss 731.0 0 0 0 0 -1.8529463879924184 P47031 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.1372244954109192 0.09774735569953917 0.4056292772293091 0.5543568730354309 44.86334063449272 40.0 1.0 no 6105 chrX_281928 18804 no_effect YJL082W 743 + TCCATCTTTTCATAGGTTAA P|249|R P|249|L P|249|A P|249|S IML2 Increased Minichromosome Loss 731.0 0 0 0 0 -1.5111067507729676 P47031 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.2762441635131836 0.3775904476642609 0.8476351499557495 0.8123628497123718 43.824996611260595 30.0 1.0 no 6106 chrX_282094 18809 no_effect YJL082W 909 + TCCTTACTTCCACCTGCAAT silent|TCC>TCG|S|304 silent|TCC>TCT|S|304 S|304|C S|304|F IML2 Increased Minichromosome Loss 731.0 0 0 0 0 1.1577775599138993 P47031 0.945252001285553 0.9294660091400146 0.0 0.0 53.509949790191115 45.0 1.0 no 6107 chrX_282168 18815 no_effect YJL082W 983 + GCTAGTTTGGAAGGCTACAA L|329|V silent|CTA>TTA|L|329 IML2 Increased Minichromosome Loss 731.0 0 0 0 0 0.04045682541226367 P47031 0.9512209892272948 0.08368295431137085 46.9744398817416 45.0 1.0 no 6108 chrX_282573r 18827 no_effect YJL082W 1391 - ATTCGTGTAAGTTGACTAAA E|470|Q E|470|K IML2 Increased Minichromosome Loss 731.0 0 0 0 0 -0.21132924665261266 P47031 0.956179976463318 0.9475290179252625 0.3349836468696594 0.4927992224693298 37.562191057057646 30.0 1.0 no 6109 chrX_282608r 18828 no_effect YJL082W 1426 - AAGCAAACTTATTAAATCAT L|481|F silent|TTG>TTA|L|481 IML2 Increased Minichromosome Loss 731.0 0 0 0 0 -1.471490982088654 P47031 0.9587849974632264 0.018324146047234532 31.8196228180276 20.0 1.0 no 6110 chrX_282651 18829 no_effect YJL082W 1466 + CGCATTGTACACTTATTTTG A|490|G A|490|V IML2 Increased Minichromosome Loss 731.0 0 0 0 0 0.32203978978444714 P47031 0.9484469890594482 0.9504740238189696 0.4374805688858032 0.02553287893533707 42.18861188908181 35.0 1.0 no 6111 chrX_282809r 18831 no_effect YJL082W 1627 - TCTATCCAATGGAAGATTTT R|549|T R|549|K D|548|H D|548|N IML2 Increased Minichromosome Loss 731.0 0 0 0 0 0.6090950109609328 P47031 0.932735025882721 0.955805003643036 0.9486550092697144 0.956179976463318 0.14885017275810242 1.0 0.005125705152750015 0.015847168862819668 40.308725495919475 30.0 1.0 no 6112 chrX_284349 18835 essential YJL081C 903 - TTCGAGCGAGGCCAATTTGC silent|TCG>TCC|S|307 silent|TCG>TCA|S|307 R|306|P R|306|H ARP4 Actin-Related Protein 489.0 0 0 0 0 -0.2015143364321968 P80428 0.2759299874305725 0.121151365339756 52.47588846212562 55.00000000000001 0.0 no 6113 chrX_284500 18837 essential YJL081C 752 - TTTCTTCCAAAGTTTTTGTT E|257|Q E|257|K E|256|Q E|256|K ARP4 Actin-Related Protein 489.0 0 0 0 0 -0.661745230000043 P80428 0.5093635320663452 0.8546510338783264 0.5019142627716064 0.7857034206390381 0.1168000027537346 -0.08760000020265579 42.2284747030767 25.0 0.0 no 6114 chrX_284880r 18843 essential YJL081C 369 + TCTTTAGAAGTGCTCTTAGA S|124|C S|124|F ARP4 Actin-Related Protein 489.0 0 0 0 0 0.5263581584386939 P80428 0.08293374627828598 0.2501851320266724 43.492110403818295 35.0 0.0 no 6115 chrX_284958r 18847 essential YJL081C 291 + CTCTATTTGAATTCCAACTC silent|CTC>CTG|L|98 silent|CTC>CTT|L|98 ARP4 Actin-Related Protein 489.0 0 0 0 0 -0.7382701604567762 P80428 41.64026355251957 35.0 0.0 no 6116 chrX_285057 18849 essential YJL081C 195 - TTCAGTTCATAATCTTTTCT silent|CTG>CTC|L|71 silent|CTG>CTA|L|71 ARP4 Actin-Related Protein 489.0 0 0 0 0 0.4333966850165116 P80428 40.93709498742346 25.0 0.0 no 6117 chrX_295542r 18866 essential YJL076W 300 - TCAATGTCTTCTTGCAAACT E|107|Q E|107|K NET1 Nucleolar silencing Establishing factor and Telophase regulator 1189.0 0 0 0 0 0.9518332121339422 P47035 0.956179976463318 0.9475290179252625 0.05348654091358185 0.043114211410284035 42.82273634574739 35.0 1.0 no 6118 chrX_295598r 18867 essential YJL076W 356 - TTACCAAAAAATCCGGATCA V|125|L V|125|I L|124|F silent|TTG>TTA|L|124 NET1 Nucleolar silencing Establishing factor and Telophase regulator 1189.0 0 0 0 0 0.8040364821534653 P47035 0.9539830088615416 0.9574310183525084 0.9587849974632264 0.05312258377671242 0.2807105779647827 0.06925523281097412 39.734071434861214 35.0 1.0 no 6119 chrX_295730 18870 essential YJL076W 485 + GAACAACGGGTCGCCCCAGT N|163|K silent|AAC>AAT|N|163 N|164|K silent|AAC>AAT|N|164 NET1 Nucleolar silencing Establishing factor and Telophase regulator 1189.0 0 1 0 0 -0.15537099595307008 P47035 0.9439849853515624 0.9439849853515624 0.0 0.2058338224887848 57.891477740262644 65.0 1.0 no 6120 chrX_295764 18872 essential YJL076W 519 + CAACAAATCCCGTCCTCTTC Q|175|E Q|175|* NET1 Nucleolar silencing Establishing factor and Telophase regulator 1189.0 0 1 0 0 0.1874334609094347 P47035 0.9590039849281312 0.9098917245864868 50.37132661429246 50.0 1.0 no 6121 chrX_296000 18884 essential YJL076W 755 + ACCTCCCATAAGAATTAGTT P|253|R P|253|L P|253|A P|253|S NET1 Nucleolar silencing Establishing factor and Telophase regulator 1189.0 0 1 0 0 -0.2960819515480122 P47035 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.06266135722398758 0.030997961759567264 0.08937259018421173 0.06380900740623474 45.50150827059736 35.0 1.0 no 6122 chrX_296275 18895 essential YJL076W 1030 + TCACTGCTCAGGACATTAAT T|345|S T|345|I silent|GTC>GTG|V|344 silent|GTC>GTT|V|344 NET1 Nucleolar silencing Establishing factor and Telophase regulator 1189.0 0 0 0 0 -0.9144136116829088 P47035 0.9491789937019348 0.9472420215606691 45.16475901415083 40.0 1.0 no 6123 chrX_296310 18896 essential YJL076W 1065 + ACCACTCCAAGAATAACATC silent|ACC>ACG|T|356 silent|ACC>ACT|T|356 T|356|S T|356|I NET1 Nucleolar silencing Establishing factor and Telophase regulator 1189.0 0 0 0 0 -0.2532158849709515 P47035 0.9491789937019348 0.9472420215606691 0.8173523545265198 0.1654716432094574 42.30069870902736 40.0 1.0 no 6124 chrX_296316r 18899 essential YJL076W 1074 - AACATTCCTGATGTTATTCT M|364|I M|364|I G|363|A G|363|E NET1 Nucleolar silencing Establishing factor and Telophase regulator 1189.0 0 1 0 0 0.583760548286973 P47035 0.9553959965705872 0.9553959965705872 0.9499930143356324 0.9438679814338684 0.23668311536312106 0.23668311536312106 0.21215780079364774 0.012492325156927107 42.82551468858139 30.0 1.0 no 6125 chrX_296347r 18902 essential YJL076W 1105 - AATCTCTGAGATTCTTGGCT E|374|D silent|GAG>GAA|E|374 E|374|Q E|374|K NET1 Nucleolar silencing Establishing factor and Telophase regulator 1189.0 0 0 0 0 -0.04397210470647995 P47035 0.94931298494339 0.956179976463318 0.9475290179252625 0.0 0.0 0.0 47.09611751774696 40.0 1.0 no 6126 chrX_296674 18914 essential YJL076W 1429 + AATCTTCAAATGGCGAATCC S|478|C S|478|F S|479|* S|479|L NET1 Nucleolar silencing Establishing factor and Telophase regulator 1189.0 0 0 0 0 -0.4386602149471656 P47035 0.945252001285553 0.9294660091400146 0.9298099875450134 42.055079530378976 40.0 1.0 no 6127 chrX_296676 18916 essential YJL076W 1431 + TCTTCAAATGGCGAATCCTG S|478|C S|478|F S|479|* S|479|L NET1 Nucleolar silencing Establishing factor and Telophase regulator 1189.0 0 0 0 0 -0.6550835934547872 P47035 0.945252001285553 0.9294660091400146 0.9298099875450134 45.09521069055575 45.0 1.0 no 6128 chrX_296772r 18919 essential YJL076W 1530 - TTCGGTTCCACAATACCGGA silent|CCG>CCC|P|516 silent|CCG>CCA|P|516 NET1 Nucleolar silencing Establishing factor and Telophase regulator 1189.0 0 0 0 0 0.4201546622412531 P47035 51.23004378086147 50.0 1.0 no 6129 chrX_296810r 18920 essential YJL076W 1568 - CTCTTACCTGATTATCATCT R|529|T R|529|K V|528|L V|528|I NET1 Nucleolar silencing Establishing factor and Telophase regulator 1189.0 0 0 0 0 0.8366682403864201 P47035 0.932735025882721 0.955805003643036 0.9539830088615416 0.9574310183525084 0.5798739790916443 0.9647799730300904 0.31992632150650024 0.20627127587795255 45.70830854177376 35.0 1.0 no 6130 chrX_297102 18927 essential YJL076W 1857 + GATCTTTTCAAAATGATCGA L|621|V L|621|F NET1 Nucleolar silencing Establishing factor and Telophase regulator 1189.0 0 0 0 0 0.3087860311421603 P47035 0.9512209892272948 0.9587849974632264 0.3053509593009949 0.195664644241333 36.8676292961996 30.0 1.0 no 6131 chrX_297240r 18930 essential YJL076W 1998 - GGCAAAATATTTCTTGGATC L|672|F silent|TTG>TTA|L|672 NET1 Nucleolar silencing Establishing factor and Telophase regulator 1189.0 0 1 0 0 0.9174047783882828 P47035 0.9587849974632264 0.04044024646282196 39.75413605102778 35.0 1.0 no 6132 chrX_297272r 18936 essential YJL076W 2030 - CCCTCTTAGCCGCACTTCTT R|683|T R|683|K R|683|S silent|AGG>AGA|R|683 NET1 Nucleolar silencing Establishing factor and Telophase regulator 1189.0 0 1 0 0 -0.14136019968162158 P47035 0.932735025882721 0.955805003643036 0.9087679982185364 0.030896157026290894 0.7942758202552795 0.024795643985271454 60.309126597444326 55.00000000000001 1.0 no 6133 chrX_297332r 18937 essential YJL076W 2090 - AATCTTCAGTACTTTTCTGT D|703|H D|703|N E|702|Q E|702|K NET1 Nucleolar silencing Establishing factor and Telophase regulator 1189.0 0 0 0 0 0.9152983670842872 P47035 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.16867417097091675 0.4161023795604706 0.0 0.0 43.35166787079596 30.0 1.0 no 6134 chrX_297608 18941 essential YJL076W 2363 + TAGCAAAATAAGTGAACAAA S|789|R silent|AGC>AGT|S|789 NET1 Nucleolar silencing Establishing factor and Telophase regulator 1189.0 0 1 0 0 0.2468661959207427 P47035 0.9417110085487366 0.5238567590713501 30.127665751967243 25.0 1.0 no 6135 chrX_297708 18945 essential YJL076W 2463 + TCGTCTTTTCCTGTTGTTGG S|822|W S|822|L S|823|C S|823|F NET1 Nucleolar silencing Establishing factor and Telophase regulator 1189.0 0 1 0 0 -0.591778344411048 P47035 0.9288619756698608 0.9298099875450134 0.945252001285553 0.9294660091400146 0.02166503295302391 0.2534066140651703 0.04138845577836037 0.04573897644877434 52.67768098161781 45.0 1.0 no 6136 chrX_297732 18946 essential YJL076W 2487 + TCTCCTTCTGTTGCTACTAA P|831|A P|831|S S|830|C S|830|F NET1 Nucleolar silencing Establishing factor and Telophase regulator 1189.0 0 1 0 0 0.3228308582772807 P47035 0.9562489986419678 0.9498909711837769 0.945252001285553 0.9294660091400146 0.6067836284637451 0.8861380815505981 0.02280152402818203 0.02342325262725353 49.917385936058395 40.0 1.0 no 6137 chrX_297735r 18949 essential YJL076W 2493 - GTTCCTTTAGTAGCAACAGA G|837|A G|837|E G|837|R G|837|R NET1 Nucleolar silencing Establishing factor and Telophase regulator 1189.0 0 1 0 0 0.34715722852602904 P47035 0.9499930143356324 0.9438679814338684 0.941340982913971 0.941340982913971 0.3114415407180786 0.3865504860877991 0.21173012256622314 0.21173012256622314 47.346367152998255 40.0 1.0 no 6138 chrX_300293 18952 essential YJL074C 2537 - ATTCTAGATCATTTTCTTGT E|852|Q E|852|K SMC3 Stability of MiniChromosomes 1230.0 0 0 0 0 0.5306194646655452 P47037 0.956179976463318 0.9475290179252625 0.4936336874961853 0.6328755021095276 41.36120992105396 25.0 0.0 no 6139 chrX_300855 18957 essential YJL074C 1975 - TCTATCACCATCTAAAGTGA R|665|T R|665|K D|664|H D|664|N SMC3 Stability of MiniChromosomes 1230.0 0 0 0 0 -0.8187864874698372 P47037 0.932735025882721 0.955805003643036 0.9486550092697144 0.956179976463318 0.1359107792377472 1.0 0.0 0.0 42.35617147505218 35.0 0.0 no 6140 chrX_301096r 18962 essential YJL074C 1731 + AACGAACTATATCGTATGAA N|578|K silent|AAC>AAT|N|578 L|580|V silent|CTA>TTA|L|580 SMC3 Stability of MiniChromosomes 1230.0 0 0 0 0 0.2256030596236447 P47037 0.9439849853515624 0.9512209892272948 0.1978815793991089 0.0 35.21442910050979 30.0 0.0 no 6141 chrX_301133r 18965 essential YJL074C 1694 + TGTCGTGGATACCGAAGAAA silent|GTC>GTG|V|566 silent|GTC>GTT|V|566 SMC3 Stability of MiniChromosomes 1230.0 0 0 0 0 -1.0429686468169344 P47037 43.12892767246739 45.0 0.0 no 6142 chrX_301139 18966 essential YJL074C 1691 - CTTCGGTATCCACGACAATG E|570|Q E|570|K SMC3 Stability of MiniChromosomes 1230.0 0 0 0 0 0.14573244101419666 P47037 0.956179976463318 0.9475290179252625 0.0371401272714138 0.030342258512973782 46.94159649231256 50.0 0.0 no 6143 chrX_301145 18968 essential YJL074C 1685 - TATCCACGACAATGTGGAAG D|568|H D|568|N silent|GTG>GTC|V|567 silent|GTG>GTA|V|567 SMC3 Stability of MiniChromosomes 1230.0 0 0 0 0 -0.5693661030379611 P47037 0.9486550092697144 0.956179976463318 0.0 0.0 42.74196349368589 45.0 0.0 no 6144 chrX_301174r 18969 essential YJL074C 1653 + ACATGTGCTGAAGTAATTGG T|552|R T|552|I SMC3 Stability of MiniChromosomes 1230.0 0 0 0 0 0.9272794718883508 P47037 0.9476869702339172 0.9472420215606691 0.30303892493247986 0.639065682888031 41.824673274303386 40.0 0.0 no 6145 chrX_301427 18970 essential YJL074C 1403 - TTTCACTCAGCTTCTGTTTG E|474|Q E|474|K S|473|T S|473|N SMC3 Stability of MiniChromosomes 1230.0 0 0 0 0 0.5017165543040051 P47037 0.956179976463318 0.9475290179252625 0.9512869715690612 0.9536849856376648 0.5826663970947266 0.9146701097488404 0.9411056637763976 0.664387047290802 48.616041830293796 40.0 0.0 no 6146 chrX_301483r 18972 essential YJL074C 1344 + ATCAATGGACCAGATACCAA I|449|M silent|ATC>ATT|I|449 SMC3 Stability of MiniChromosomes 1230.0 0 0 0 0 0.7100798379556099 P47037 0.9598389863967896 0.08330031484365462 44.035942944233 40.0 0.0 no 6147 chrX_301498r 18973 essential YJL074C 1329 + GAGCTAATTGATTCTATCAA L|445|V silent|CTA>TTA|L|445 SMC3 Stability of MiniChromosomes 1230.0 0 0 0 0 -0.4745590927850045 P47037 0.9512209892272948 0.027819627895951268 38.60719257697474 30.0 0.0 no 6148 chrX_301656 18975 essential YJL074C 1174 - TTCATCCTTTGATTTAAAAC E|398|Q E|398|K D|397|H D|397|N SMC3 Stability of MiniChromosomes 1230.0 0 0 0 0 -0.0009039768817672713 P47037 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.07636076211929321 0.07117194682359695 0.049200352281332016 0.18121764063835144 36.3755696519197 25.0 0.0 no 6149 chrX_301704 18977 essential YJL074C 1126 - ATCTCTCTGCTTTTGTTGCA D|382|H D|382|N R|381|T R|381|K SMC3 Stability of MiniChromosomes 1230.0 0 0 0 0 0.2272657457127409 P47037 0.9486550092697144 0.956179976463318 0.932735025882721 0.955805003643036 0.5617713332176208 0.4092848002910614 0.4109393060207367 0.6153184175491333 52.357346878502476 40.0 0.0 no 6150 chrX_301806r 18979 essential YJL074C 1021 + TCAAATCTATAATTGAGCAA I|341|M silent|ATC>ATT|I|341 S|343|C S|343|F SMC3 Stability of MiniChromosomes 1230.0 0 0 0 0 -0.1070854126744426 P47037 0.9598389863967896 0.945252001285553 0.9294660091400146 0.13769418001174927 0.025805987417697903 0.0257943831384182 34.240338291189396 25.0 0.0 no 6151 chrX_302036 18982 essential YJL074C 794 - CCTCTCTTTTATCCAACTCC E|271|Q E|271|K E|271|D silent|GAG>GAA|E|271 SMC3 Stability of MiniChromosomes 1230.0 0 0 0 0 0.2265805499127793 P47037 0.956179976463318 0.9475290179252625 0.94931298494339 0.0 0.0 0.0 52.506837340535576 45.0 0.0 no 6152 chrX_302054r 18984 essential YJL074C 773 + CTCTTCCGAACAATACATCC S|259|C S|259|F S|260|C S|260|F SMC3 Stability of MiniChromosomes 1230.0 0 0 0 0 0.2536353065782562 P47037 0.945252001285553 0.9294660091400146 0.945252001285553 0.9294660091400146 0.05067242309451103 0.048678919672965996 0.1797347068786621 0.6868168115615845 46.00786617349434 45.0 0.0 no 6153 chrX_302471r 18991 essential YJL074C 356 + TGACAGAAACGTGACCAAAG D|120|E silent|GAC>GAT|D|120 SMC3 Stability of MiniChromosomes 1230.0 0 0 0 0 0.14438305663109866 P47037 0.9532920122146606 0.29803773760795593 39.196572003615415 45.0 0.0 no 6154 chrX_302550 18994 essential YJL074C 280 - ATCTCCTCTCGAAAGTACAC D|100|H D|100|N G|99|A G|99|E SMC3 Stability of MiniChromosomes 1230.0 0 0 0 0 -0.22461603040947647 P47037 0.9486550092697144 0.956179976463318 0.9499930143356324 0.9438679814338684 0.04010200873017311 0.31669405102729803 0.6647444367408752 0.8931198120117188 46.08764002899494 45.0 0.0 no 6155 chrX_302676r 19001 essential YJL074C 151 + ACGATTACTCTAATCTTAAG D|51|E silent|GAC>GAT|D|51 SMC3 Stability of MiniChromosomes 1230.0 0 0 0 0 -0.33151701620967816 P47037 0.9532920122146606 0.0 36.13541441275396 30.0 0.0 no 6156 chrX_305573 19012 essential YJL072C 270 - TCTTTCGTCGTTAACCACTG E|97|Q E|97|K silent|ACG>ACC|T|95 silent|ACG>ACA|T|95 0 0 0 0 -0.6240067933503973 P40359 0.9435089826583862 0.9307000041007996 0.6952230930328369 0.9871208667755128 47.988455420791645 45.0 0.0 no 6157 chrX_305587r 19013 essential YJL072C 253 + GCAGTATTGTAGCACCACAG C|85|W silent|TGC>TGT|C|85 0 0 0 0 0.0110247301965341 P40359 0.9199889898300172 0.0008048566523939371 32.031360626220696 51.19345845796232 50.0 0.0 no 6158 chrX_311423 19018 essential YJL069C 1264 - CGCGTTTACAGCAATTAAAA A|428|P A|428|T UTP18 U Three Protein 594.0 0 0 0 0 0.12664964619253466 P40362 0.9573720097541808 0.9523990154266356 0.2643176317214966 0.7432558536529541 39.02499698717571 35.0 0.0 no 6159 chrX_311532r 19022 essential YJL069C 1152 + AACATTTTACATTCCACTTC N|385|K silent|AAC>AAT|N|385 UTP18 U Three Protein 594.0 0 0 0 0 0.1307453988348534 P40362 0.9439849853515624 0.012828311882913113 41.367993954234464 30.0 0.0 no 6160 chrX_311572r 19024 essential YJL069C 1112 + CCATGGAATTGTCCTTTTAC H|372|D H|372|Y UTP18 U Three Protein 594.0 0 0 0 0 0.6663636661379173 P40362 0.9473130106925964 0.9489949941635132 0.24586166441440585 0.039116736501455314 46.52241643205929 40.0 0.0 no 6161 chrX_311911r 19029 essential YJL069C 773 + TTCTAAGCCTCTACTGTTAA S|259|C S|259|F UTP18 U Three Protein 594.0 0 0 0 0 -0.4688732410789069 P40362 0.945252001285553 0.9294660091400146 0.012618054635822771 0.007391040679067373 44.818436734751295 35.0 0.0 no 6162 chrX_311999 19032 essential YJL069C 688 - CACAATGTCAAGTTTCTTAG V|236|L V|236|M UTP18 U Three Protein 594.0 0 0 0 0 -0.3984531647906032 P40362 0.9539830088615416 0.9587630033493042 0.2830348610877991 0.0996951088309288 39.60008211484421 35.0 0.0 no 6163 chrX_312266 19036 essential YJL069C 421 - TCTTAATTTCTTTGTCTTAT R|147|T R|147|K UTP18 U Three Protein 594.0 0 0 0 0 0.09808472090637928 P40362 0.932735025882721 0.955805003643036 0.0105076115578413 0.20432905852794647 38.65894359973913 20.0 0.0 no 6164 chrX_312352r 19037 essential YJL069C 332 + TTCAAGCGATGATTATTCTG S|112|* S|112|L S|113|R silent|AGC>AGT|S|113 UTP18 U Three Protein 594.0 0 0 0 0 -0.7561110901198089 P40362 0.9298099875450134 0.9417110085487366 0.2971939444541931 0.11891727149486543 40.45550611590676 35.0 0.0 no 6165 chrX_312380 19038 essential YJL069C 307 - ATCTTCGTCATCCACGTCCA D|109|H D|109|N E|108|Q E|108|K UTP18 U Three Protein 594.0 0 0 0 0 -1.2272620962562493 P40362 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.08172144740819931 0.2773765325546265 0.4981724321842194 0.7797512412071228 55.74545142445272 50.0 0.0 no 6166 chrX_312624r 19040 essential YJL069C 60 + TTACTAGCCAAATTTGTATT L|22|V silent|CTA>TTA|L|22 UTP18 U Three Protein 594.0 0 0 0 0 -0.4786959703425029 P40362 0.9512209892272948 0.0 39.32312640957901 25.0 0.0 no 6167 chrX_320088 19042 essential YJL061W 72 + TACATTTTTAGTTCTCAGAA Y|25|* silent|TAC>TAT|Y|25 NUP82 NUclear Pore 713.0 0 0 0 0 1.0974859478022625 P40368 38.26782147216966 25.0 1.0 no 6168 chrX_320693r 19050 essential YJL061W 680 - ACATTACTAAAGATTTGTTT M|233|I M|233|I V|232|L V|232|I NUP82 NUclear Pore 713.0 0 0 0 0 -0.4016602082420888 P40368 0.2783786952495575 0.2783786952495575 0.8950080871582031 1.0 0.220660001039505 0.220660001039505 -0.6425399780273438 -0.7155200242996216 1.5618000030517578 1.5618000030517578 -0.8823999762535095 -0.7084000110626221 0.7113199830055237 0.2295600026845932 34.2849014170618 20.0 1.0 no 6169 chrX_320722r 19054 essential YJL061W 709 - AACATCTGTTGTAGAATCCA V|243|L V|243|I D|242|H D|242|N NUP82 NUclear Pore 713.0 0 0 0 0 -0.3222409999160033 P40368 0.3915309309959412 0.2609265148639679 0.1205720752477646 0.5584781169891357 -0.3709999918937683 -0.2940999865531921 4.65746021270752 3.980639934539795 -0.8726000189781189 -0.6064000129699707 42.88575701769104 35.0 1.0 no 6170 chrX_320923 19058 essential YJL061W 907 + CAACCATACTAATTGATAAT T|304|S T|304|I silent|ACC>ACG|T|304 silent|ACC>ACT|T|304 NUP82 NUclear Pore 713.0 0 0 0 0 -0.1960423411145107 P40368 0.7810006141662598 0.3289468288421631 1.775439977645874 0.9166200160980223 34.66300267653401 25.0 1.0 no 6171 chrX_320926r 19059 essential YJL061W 913 - TTGCCCATTATCAATTAGTA silent|GGG>GGC|G|310 silent|GGG>GGA|G|310 G|310|A G|310|E NUP82 NUclear Pore 713.0 0 0 0 0 -0.1812778729956404 P40368 0.1322777271270752 0.18028604984283447 0.0949999988079071 0.4621799886226654 44.34760251241249 30.0 1.0 no 6172 chrX_334338r 19069 essential YJL054W 76 - CCTCAAGGCGGGTATACCAA L|31|F silent|TTG>TTA|L|31 R|32|T R|32|K TIM54 Translocase of the Inner Mitochondrial membrane 478.0 0 0 0 0 -1.652728683528845 P47045 0.9587849974632264 0.932735025882721 0.955805003643036 0.3017983436584473 0.02455740235745907 1.0 52.65309534399751 55.00000000000001 1.0 no 6173 chrX_334456r 19075 essential YJL054W 194 - GCTTCACCAAGTCTGTTGCA K|71|N silent|AAG>AAA|K|71 silent|GTG>GTC|V|70 silent|GTG>GTA|V|70 TIM54 Translocase of the Inner Mitochondrial membrane 478.0 0 0 0 0 -0.2385543415196075 P47045 0.9355990290641784 0.0320635661482811 54.95249468290854 50.0 1.0 no 6174 chrX_334494r 19078 essential YJL054W 232 - TGGCACTTTGTCTACCTCCA silent|GTG>GTC|V|83 silent|GTG>GTA|V|83 V|83|L V|83|M TIM54 Translocase of the Inner Mitochondrial membrane 478.0 0 0 0 0 0.5016271801574224 P47045 0.9539830088615416 0.9587630033493042 0.4195838868618012 0.13272592425346375 56.73961866787619 50.0 1.0 no 6175 chrX_334540 19079 essential YJL054W 275 + ACCTCCTCCAAATGATTATC P|93|R P|93|L P|93|A P|93|S TIM54 Translocase of the Inner Mitochondrial membrane 478.0 0 0 0 0 -0.5143997107949085 P47045 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 46.85470478854677 40.0 1.0 no 6176 chrX_334595 19081 essential YJL054W 330 + AAGCCTGTACTGTATTATGC P|112|A P|112|S P|112|R P|112|L TIM54 Translocase of the Inner Mitochondrial membrane 478.0 0 0 0 0 0.040233264005601684 P47045 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.06362839043140411 0.04412670060992241 0.04124197736382485 0.02070925012230873 46.6850354313616 40.0 1.0 no 6177 chrX_334838 19084 essential YJL054W 573 + GACTCGTTTGATCCAGAAAT D|192|E silent|GAC>GAT|D|192 S|193|W S|193|L TIM54 Translocase of the Inner Mitochondrial membrane 478.0 0 0 0 0 0.2027025278050673 P47045 0.9532920122146606 0.9288619756698608 0.9298099875450134 1.0 0.015365002676844597 0.2462625503540039 43.56717519740072 40.0 1.0 no 6178 chrX_336047r 19099 exception YJL053W 152 - TCAAAGTAACAATTCCACCA L|57|F silent|TTG>TTA|L|57 PEP8 carboxyPEPtidase Y-deficient 379.0 0 0 0 0 0.8355281162772439 P40335 0.9798439741134644 0.0074428622610867015 41.508738577209954 35.0 1.0 no 6179 chrX_336495 19104 exception YJL053W 597 + GCAACCACTAATGACATCGC A|200|G A|200|V T|201|S T|201|I PEP8 carboxyPEPtidase Y-deficient 379.0 0 1 0 0 0.3453345407403128 P40335 0.9672009944915771 0.9664270281791688 0.9665899872779846 0.9646379947662354 0.14000000059604645 0.40400001406669617 -0.4300000071525574 0.38960000872612 47.063909269122064 50.0 1.0 no 6180 chrX_336499r 19106 exception YJL053W 604 - ACCACCAGCGATGTCATTAG G|208|R G|208|S G|208|A G|208|D PEP8 carboxyPEPtidase Y-deficient 379.0 0 1 0 0 0.3750753290704105 P40335 0.9477360248565674 0.9668909907341005 0.9656509757041932 0.9535760283470154 1.806399941444397 4.072999954223634 2.3919999599456787 4.1192002296447745 50.96532417407639 50.0 1.0 no 6181 chrX_336551 19109 exception YJL053W 653 + CACGCAAACAAAGAGCACCC T|219|R T|219|M Q|220|E Q|220|* PEP8 carboxyPEPtidase Y-deficient 379.0 0 1 0 0 -0.23228384401898106 P40335 0.9528260231018066 0.9669359922409058 0.9786580204963684 46.90149644325862 55.00000000000001 1.0 no 6182 chrX_336568r 19110 exception YJL053W 673 - AACGTCTGCCGCCTCACCCT V|231|L V|231|I D|230|H D|230|N PEP8 carboxyPEPtidase Y-deficient 379.0 0 0 0 0 0.06853621959474665 P40335 0.9629039764404296 0.9705730080604552 0.9559190273284912 0.96840500831604 0.4416925013065338 0.9113925695419312 0.4496188163757324 0.5965111255645752 -0.41359999775886536 -0.4560000002384186 63.09252262120748 65.0 1.0 no 6183 chrX_336633r 19113 exception YJL053W 738 - ATACCTATATCCAATCTAAC G|252|A G|252|D G|252|R G|252|S PEP8 carboxyPEPtidase Y-deficient 379.0 0 0 0 0 0.6582853883910005 P40335 0.9094370007514954 0.8989760279655457 0.8943480253219604 0.9106770157814026 0.0 0.0 0.0 0.0 39.676448849456 30.0 1.0 no 6184 chrX_342756r 19117 essential YJL050W 237 - TCGAACGAATCTGCCAACAC E|86|Q E|86|K silent|TCG>TCC|S|84 silent|TCG>TCA|S|84 MTR4 Mrna TRansport 1073.0 0 1 0 0 -1.4318962901909984 P47047 0.956179976463318 0.9475290179252625 0.5389744043350221 0.5578997135162354 44.75558490760949 50.0 1.0 no 6185 chrX_342832r 19119 essential YJL050W 313 - ACCGTCTTGCTCAACTTGTA G|111|R G|111|S G|111|A G|111|D MTR4 Mrna TRansport 1073.0 0 1 0 0 0.7950486773541412 P47047 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.4285702705383301 0.7705286741256714 0.6608043909072876 0.5287721157073975 51.096617133945294 45.0 1.0 no 6186 chrX_343410r 19129 essential YJL050W 891 - TCAGCAAACTCCATTGCATT E|304|Q E|304|K A|303|P A|303|T MTR4 Mrna TRansport 1073.0 0 0 0 0 0.1484767180363872 P47047 0.956179976463318 0.9475290179252625 0.9573720097541808 0.9523990154266356 0.0482550747692585 0.06747439503669739 0.0065864850766956815 0.005309125874191523 47.3060317499793 40.0 1.0 no 6187 chrX_343623 19134 essential YJL050W 1101 + CCAAATTCCACTGATTCAAG P|368|R P|368|L MTR4 Mrna TRansport 1073.0 0 0 0 0 -1.5438959079570165 P47047 0.9432820081710817 0.9430609941482544 0.4800010919570923 0.3720302879810333 42.47459599516566 40.0 1.0 no 6188 chrX_343597r 19135 essential YJL050W 1078 - ATCACCTATCTGGTTACTTA D|366|H D|366|N G|365|A G|365|D MTR4 Mrna TRansport 1073.0 0 0 0 0 0.7282719809547331 P47047 0.9486550092697144 0.956179976463318 0.9499930143356324 0.9446240067481996 0.1133781000971794 0.557034432888031 0.936295449733734 0.3271206021308899 46.56639450644724 35.0 1.0 no 6189 chrX_343623r 19136 essential YJL050W 1104 - CCTCTTGAATCAGTGGAATT R|374|T R|374|K G|375|R G|375|S MTR4 Mrna TRansport 1073.0 0 0 0 0 -0.9148659074465226 P47047 0.932735025882721 0.955805003643036 0.941340982913971 0.951104998588562 0.3514842689037323 1.0 0.2608948051929474 0.2497412860393524 44.842817507752216 40.0 1.0 no 6190 chrX_343675r 19139 essential YJL050W 1156 - ACCTTTTGCGTCACCCTTAG G|392|R G|392|S G|392|A G|392|D MTR4 Mrna TRansport 1073.0 0 0 0 0 -0.9210357520951928 P47047 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.007346254773437977 1.0 0.08652128279209137 0.016824154183268547 55.262468819421365 50.0 1.0 no 6191 chrX_343917r 19142 essential YJL050W 1398 - CCGATACCTCTTCTTAATAA G|473|R G|473|S G|471|A G|471|D MTR4 Mrna TRansport 1073.0 0 0 0 0 -2.0843836926635158 P47047 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.00200949190184474 0.013401903212070463 0.0 0.0 43.14590074524125 35.0 1.0 yes 6192 chrX_343962r 19144 essential YJL050W 1443 - TCAATGACTTCCTTCAAAAT E|488|Q E|488|K MTR4 Mrna TRansport 1073.0 0 0 0 0 -0.8161652079404134 P47047 0.956179976463318 0.9475290179252625 0.0 0.0 38.77393471544133 30.0 1.0 no 6193 chrX_344214r 19153 essential YJL050W 1695 - ACCATTCCTTTAGCAACTTG M|571|I M|571|I V|572|L V|572|I MTR4 Mrna TRansport 1073.0 0 0 0 0 -0.6848728387526053 P47047 0.9553959965705872 0.9553959965705872 0.9539830088615416 0.9574310183525084 1.0 1.0 0.5420435667037964 0.2554766535758972 47.66360087937153 40.0 1.0 no 6194 chrX_344376r 19157 essential YJL050W 1857 - GCAAGTTTCTTTTCCATAAC A|626|P A|626|T MTR4 Mrna TRansport 1073.0 0 0 0 0 -0.07544268754332441 P47047 0.9573720097541808 0.9523990154266356 0.24951842427253726 0.556898832321167 43.8568372991441 35.0 1.0 no 6195 chrX_344501 19160 essential YJL050W 1979 + TCGTCAAGTTGTCACCCATC R|661|G R|661|C Q|662|E Q|662|* MTR4 Mrna TRansport 1073.0 0 0 0 0 1.4170852213198264 P47047 0.8994590044021606 0.8926740288734436 0.9590039849281312 0.032915614545345306 0.005882380064576864 1.0 53.01253612554973 50.0 1.0 no 6196 chrX_344529 19163 essential YJL050W 2007 + GCCTTAAGTTTCCTACAACC silent|GCC>GCG|A|670 silent|GCC>GCT|A|670 A|670|G A|670|V MTR4 Mrna TRansport 1073.0 0 0 0 0 -1.1814943276333647 P47047 0.9484469890594482 0.9504740238189696 0.007214474957436323 0.8828089833259583 50.2977632831832 45.0 1.0 no 6197 chrX_344668r 19167 essential YJL050W 2149 - GACGACCACATTGACAATAT V|723|L V|723|I V|722|L V|722|I MTR4 Mrna TRansport 1073.0 0 0 0 0 -0.31871195001233776 P47047 0.9539830088615416 0.9574310183525084 0.9539830088615416 0.9574310183525084 1.0 0.14523400366306305 1.0 0.07083027809858322 42.07253221434485 40.0 1.0 no 6198 chrX_344733 19169 essential YJL050W 2211 + TTCAACCCTACCTTACCAGA F|738|L silent|TTC>TTT|F|738 N|739|K silent|AAC>AAT|N|739 MTR4 Mrna TRansport 1073.0 0 0 0 0 0.5840760528440556 P47047 0.9387490153312684 0.9439849853515624 0.6603047251701355 0.9154396057128906 51.90738679979057 45.0 1.0 no 6199 chrX_344734 19170 essential YJL050W 2212 + TCAACCCTACCTTACCAGAA F|738|L silent|TTC>TTT|F|738 N|739|K silent|AAC>AAT|N|739 MTR4 Mrna TRansport 1073.0 0 0 0 0 0.6710760940146223 P47047 0.9387490153312684 0.9439849853515624 0.6603047251701355 0.9154396057128906 50.079602565812024 45.0 1.0 no 6200 chrX_344792 19173 essential YJL050W 2270 + TGCTGTTATTCCCATAACTT A|758|G A|758|V MTR4 Mrna TRansport 1073.0 0 0 0 0 -0.1980910375059416 P47047 0.9484469890594482 0.9504740238189696 0.3805156946182251 0.3166818916797638 47.57974148087306 35.0 1.0 no 6201 chrX_344854r 19174 essential YJL050W 2335 - ACCGCTGGCTCTAATATCTT G|785|R G|785|S G|785|A G|785|D MTR4 Mrna TRansport 1073.0 0 0 0 0 -2.3891058467992736 P47047 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.241614043712616 0.5167111158370972 0.4968162477016449 0.8246268630027771 51.18182899921385 45.0 1.0 yes 6202 chrX_344884 19175 essential YJL050W 2362 + AAACTGTTGGGAAGTCTTTA T|789|S T|789|I MTR4 Mrna TRansport 1073.0 0 0 0 0 0.26164719951561743 P47047 0.9491789937019348 0.9472420215606691 1.0 0.15666848421096802 41.04829153199989 35.0 1.0 no 6203 chrX_344869r 19176 essential YJL050W 2350 - AACAGTTTCTTTTTGACCGC V|790|L V|790|I MTR4 Mrna TRansport 1073.0 0 0 0 0 1.4900742908348323 P47047 0.9539830088615416 0.9574310183525084 0.3483613133430481 0.07474945485591887 46.76935298275664 40.0 1.0 no 6204 chrX_370046 19182 essential YJL039C 3734 - CTCTTTTAATCAGGCGCATA R|1251|T R|1251|K NUP192 NUclear Pore 1683.0 0 0 0 0 0.7787567923116561 P47054 0.02219549939036369 0.29154065251350403 46.58161816452275 40.0 0.0 no 6205 chrX_370338r 19186 essential YJL039C 3439 + TTCTGTCATTCTTAGCCTAC L|1148|V silent|CTG>TTG|L|1148 S|1149|* S|1149|L NUP192 NUclear Pore 1683.0 0 0 0 0 0.10298381364743693 P47054 0.059104133397340775 0.6182767152786255 49.57305746346549 40.0 0.0 no 6206 chrX_370718r 19199 essential YJL039C 3059 + TCATCTGTTATTAGGTTTCC H|1021|D H|1021|Y L|1022|V silent|CTG>TTG|L|1022 NUP192 NUclear Pore 1683.0 0 0 0 0 0.7213211496788132 P47054 0.0 0.0 0.08282208442687987 46.7946646223412 35.0 0.0 no 6207 chrX_370726r 19200 essential YJL039C 3051 + ACTATTTCTCATCTGTTATT T|1018|S T|1018|I NUP192 NUclear Pore 1683.0 0 0 0 0 0.03220309811642677 P47054 0.39565739035606384 0.008890983648598194 41.586175277219006 25.0 0.0 no 6208 chrX_371007r 19205 essential YJL039C 2770 + CACACTTGGGTTTATACGTC H|925|D H|925|Y H|925|Q silent|CAC>CAT|H|925 NUP192 NUclear Pore 1683.0 0 0 0 0 0.011196690793844331 P47054 0.7595712542533875 0.6846656799316406 0.3851658701896668 1.675179958343506 0.9736599922180176 -0.11377999931573868 46.77498416036542 45.0 0.0 no 6209 chrX_371020r 19206 essential YJL039C 2757 + ATTCCACTTGTTGCACACTT P|921|A P|921|S P|921|R P|921|L NUP192 NUclear Pore 1683.0 0 0 0 0 0.3147933606597453 P47054 0.13161253929138186 0.5596228837966919 0.07759688794612885 0.036798764020204544 2.6206800937652592 3.534820079803467 2.064039945602417 2.222640037536621 50.3112096308185 40.0 0.0 no 6210 chrX_371569 19215 essential YJL039C 2211 - TATCCCTGACCTAATCTTGT G|743|A G|743|E G|743|R G|743|R NUP192 NUclear Pore 1683.0 0 0 0 0 0.8614436801596661 P47054 0.4507019519805908 0.3056129217147827 0.13826477527618408 0.13826477527618408 49.903117095303905 40.0 0.0 no 6211 chrX_371678r 19217 essential YJL039C 2099 + AACAAAATACTCTGACGTTT T|701|R T|701|I NUP192 NUclear Pore 1683.0 0 0 0 0 1.1622792868360134 P47054 0.118244506418705 0.114999420940876 36.17551205387235 30.0 0.0 no 6212 chrX_371756r 19219 essential YJL039C 2021 + TCTAGACTCTCTAATTTTCA L|675|V silent|CTA>TTA|L|675 D|676|E silent|GAC>GAT|D|676 NUP192 NUclear Pore 1683.0 0 0 0 0 0.03258495219784308 P47054 0.04015834257006645 0.2637438178062439 41.40386528998687 30.0 0.0 no 6213 chrX_371794 19220 essential YJL039C 1986 - GTTCTAGAAGATTCAAGTTT R|668|T R|668|K NUP192 NUclear Pore 1683.0 0 0 0 0 0.3819245768330219 P47054 0.017007702961564064 0.39486309885978704 39.07172998588021 30.0 0.0 no 6214 chrX_371991 19223 essential YJL039C 1789 - TTCATTTAAGCCTTCTTCTA E|603|Q E|603|K NUP192 NUclear Pore 1683.0 0 0 0 0 0.4457773823410028 P47054 0.030652547255158424 0.024236114695668217 45.206716261297466 30.0 0.0 no 6215 chrX_371950r 19224 essential YJL039C 1827 + TCTTCTTTATTAACTTTAGT S|610|C S|610|F S|611|C S|611|F NUP192 NUclear Pore 1683.0 0 0 0 0 0.4150059057606511 P47054 0.009599845856428145 0.004175866954028606 0.01886790059506893 0.008846169337630272 37.57782002859108 20.0 0.0 no 6216 chrX_372050 19227 essential YJL039C 1730 - CACTAAACTGCTGCCTCTTA S|583|T S|583|N NUP192 NUclear Pore 1683.0 0 0 0 0 -0.4134084396325398 P47054 0.84522545337677 1.0 48.64445193031918 45.0 0.0 no 6217 chrX_372709 19236 essential YJL039C 1071 - TCATCATCAAGTAACTGTTT E|364|Q E|364|K D|363|H D|363|N NUP192 NUclear Pore 1683.0 0 0 0 0 0.7891882730926192 P47054 0.3299934864044189 0.1617065817117691 0.13626675307750702 0.4964039027690888 40.240235968725294 30.0 0.0 no 6218 chrX_372721 19237 essential YJL039C 1059 - AACTGTTTAGGAATTAGCCT Q|359|H silent|CAG>CAA|Q|359 NUP192 NUclear Pore 1683.0 0 0 0 0 -0.6344258255564138 P47054 0.15738090872764587 43.68653724909029 35.0 0.0 no 6219 chrX_372902 19239 essential YJL039C 878 - TCGTGTCAGCCCTTCTTTTA silent|ACG>ACC|T|299 silent|ACG>ACA|T|299 D|298|H D|298|N NUP192 NUclear Pore 1683.0 0 0 0 0 -0.4226473729350128 P47054 0.12878893315792084 0.5261206030845642 55.791503822539035 45.0 0.0 no 6220 chrX_373007r 19240 essential YJL039C 770 + TCAGTTTATGAAAGACTTAA Q|258|E Q|258|* NUP192 NUclear Pore 1683.0 0 0 0 0 -0.7204224023134057 P47054 0.8279435038566589 34.12276726856658 25.0 0.0 no 6221 chrX_373204r 19244 essential YJL039C 573 + ATTCTGAGTCAAATTTTATA L|193|V silent|CTG>TTG|L|193 NUP192 NUclear Pore 1683.0 0 0 0 0 1.0479465038093347 P47054 0.0 34.81668579546113 20.0 0.0 no 6222 chrX_373196r 19245 essential YJL039C 581 + TCAAATTTTATATGGTTTAG Q|195|E Q|195|* NUP192 NUclear Pore 1683.0 0 0 0 0 0.5952214711681755 P47054 1.0 33.070108382402914 20.0 0.0 no 6223 chrX_373488 19246 essential YJL039C 292 - TACTTTGCCATTATTAGCGG V|104|L V|104|I NUP192 NUclear Pore 1683.0 0 0 0 0 -0.6485599202042089 P47054 0.4666051268577576 0.8630262613296509 46.95447814021362 40.0 0.0 no 6224 chrX_373595r 19248 essential YJL039C 182 + CTCTACTTTTAAGGTCAATC S|62|C S|62|F T|63|S T|63|I NUP192 NUclear Pore 1683.0 0 0 0 0 0.045221934863069364 P47054 0.07032168656587601 0.08619166165590286 0.18093352019786835 0.5830454230308533 40.83875470065613 35.0 0.0 no 6225 chrX_380447r 19249 essential YJL035C 532 + ACACGTTTCCGCCTATGGAA T|179|R T|179|M N|178|K silent|AAC>AAT|N|178 0 0 0 0 -0.2338336375476751 P47058 0.9476869702339172 0.9502379894256592 0.9439849853515624 0.5121265649795532 0.1060464009642601 0.9042806029319764 51.914659657265865 50.0 0.0 no 6226 chrX_380556 19252 essential YJL035C 426 - GCTTCTTTCCTCAAGATCCC A|149|P A|149|T E|148|Q E|148|K 0 0 0 0 -2.1838478303783795 P47058 0.9573720097541808 0.9523990154266356 0.956179976463318 0.9475290179252625 0.02677834779024124 0.019030947238206863 0.0 0.0 55.94037818174888 50.0 0.0 yes 6227 chrX_380591 19255 essential YJL035C 391 - CCCTGCCGCACTATTGTTCT G|137|R G|137|R G|137|A G|137|E 0 0 0 0 -0.6836942665088113 P47058 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.5429486632347107 0.5429486632347107 0.7614669799804688 1.0 59.421953103518035 55.00000000000001 0.0 no 6228 chrX_380592 19257 essential YJL035C 390 - CCTGCCGCACTATTGTTCTT G|137|R G|137|R A|136|P A|136|T 0 0 0 0 -0.09763643305934896 P47058 0.941340982913971 0.941340982913971 0.9573720097541808 0.9523990154266356 0.5429486632347107 0.5429486632347107 1.0 0.30833700299263 3.1689999103546143 0.4092000126838684 56.18603240642619 50.0 0.0 no 6229 chrX_380700r 19261 essential YJL035C 279 + GCTCTCAAGCAATTAGACAT L|95|V L|95|F A|94|G A|94|V 0 1 0 0 -0.8188964405696899 P47058 0.9512209892272948 0.9587849974632264 0.9484469890594482 0.9504740238189696 0.0 0.0 0.07195943593978882 0.1956057846546173 1.5740000009536743 -0.20880000293254847 44.50578903264983 40.0 0.0 no 6230 chrX_380721 19262 essential YJL035C 261 - GCAGATGCACACATTATACA A|94|P A|94|T 0 1 0 0 -4.178582505983611 P47058 0.9573720097541808 0.9523990154266356 0.056686487048864365 0.09922254830598833 3.893599987030029 0.9854000210762024 44.842003335667584 40.0 0.0 yes 6231 chrX_380774 19263 essential YJL035C 208 - GAACACGTCAACAACTCCTC silent|GTG>GTC|V|75 silent|GTG>GTA|V|75 V|75|L V|75|M 0 0 0 1 -0.2803363710777333 P47058 0.9539830088615416 0.9587630033493042 0.728297770023346 0.2462547719478607 -0.9715999960899352 -0.84579998254776 45.70650794728698 50.0 0.0 no 6232 chrX_381429 19273 essential YJL034W 102 + TCCTCCAATGTTTTAGTTAG silent|TCC>TCG|S|35 silent|TCC>TCT|S|35 S|35|C S|35|F KAR2 KARyogamy 682.0 0 0 0 0 0.4882896107570272 P16474 0.945252001285553 0.9294660091400146 45.63408606290562 35.0 1.0 no 6233 chrX_381430r 19274 essential YJL034W 106 - ACCTCTAACTAAAACATTGG G|42|R G|42|S G|42|A G|42|D KAR2 KARyogamy 682.0 0 0 0 0 -1.0171981472256224 P16474 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.4112823605537415 0.6240749359130859 1.0 0.5601912140846252 38.22571245185213 35.0 1.0 no 6234 chrX_381698 19277 essential YJL034W 371 + TAACGACAGATCTGTTCAGA N|125|K silent|AAC>AAT|N|125 D|126|E silent|GAC>GAT|D|126 KAR2 KARyogamy 682.0 0 0 0 0 -0.394547459260056 P16474 0.9439849853515624 0.9532920122146606 0.0902184396982193 0.13987581431865692 -0.3659999966621399 1.9290200471878047 42.2241984709168 40.0 1.0 no 6235 chrX_381735r 19279 essential YJL034W 411 - TCTTTATTAACCACATTAAA D|144|H D|144|N KAR2 KARyogamy 682.0 0 0 0 0 0.6288129654653287 P16474 0.9486550092697144 0.956179976463318 0.03670094534754753 0.6288079619407654 -0.02786000072956085 0.0797400027513504 34.87897003419681 20.0 1.0 no 6236 chrX_381810r 19281 essential YJL034W 486 - ATCATACCAGAAATTTCTTC M|168|I M|168|I G|167|A G|167|D KAR2 KARyogamy 682.0 0 0 0 0 -0.1345144210036094 P16474 0.9553959965705872 0.9553959965705872 0.9499930143356324 0.9446240067481996 0.02936578169465065 0.02936578169465065 1.0 0.002337384037673473 1.5547000169754028 1.5547000169754028 -0.4470199942588806 9.150480270385742 39.38381884200391 30.0 1.0 no 6237 chrX_382040 19285 essential YJL034W 713 + TCAAATTATTGTTTATGATT Q|239|E Q|239|* KAR2 KARyogamy 682.0 0 0 0 0 -0.6121531311115761 P16474 0.9590039849281312 0.042787924408912666 1.935920000076294 32.52153827528912 15.0 1.0 no 6238 chrX_382110 19286 essential YJL034W 783 + TTCGAAGTCCAAGCCACTTC F|262|L silent|TTC>TTT|F|262 KAR2 KARyogamy 682.0 0 0 0 0 1.7583488742111684 P16474 0.9387490153312684 0.02371155098080635 1.7637799978256226 2.4233241081237797 50.8042447014422 50.0 1.0 no 6239 chrX_382125 19287 essential YJL034W 798 + ACTTCTGGTGATACTCATTT T|267|S T|267|I S|268|C S|268|F KAR2 KARyogamy 682.0 0 0 0 0 -0.15181683435811386 P16474 0.9491789937019348 0.9472420215606691 0.945252001285553 0.9294660091400146 0.0659286230802536 0.001560101518407464 0.07368947565555573 0.03614858910441399 0.6082000136375427 -1.67467999458313 -0.3401800096035004 0.021139999851584438 45.23817397321227 35.0 1.0 no 6240 chrX_382237r 19288 essential YJL034W 913 - TTCTCTCTTCAATTTAGCTA E|311|Q E|311|K R|310|T R|310|K KAR2 KARyogamy 682.0 0 0 0 0 -0.23002023689535875 P16474 0.956179976463318 0.9475290179252625 0.932735025882721 0.955805003643036 0.08168555796146393 0.04685108363628388 0.9655372500419616 0.8360316157341003 -0.21065999567508695 -0.7416800260543823 2.0209200382232666 0.6039800047874451 1.3029999732971191 2.967400074005127 3.8059999942779537 0.8855999708175659 43.81589304552063 30.0 1.0 no 6241 chrX_382289r 19290 essential YJL034W 965 - TTTCAATACGGGTGGACATT E|328|Q E|328|K KAR2 KARyogamy 682.0 0 0 0 0 -0.7340489949892667 P16474 0.956179976463318 0.9475290179252625 0.028450727462768555 0.032353412359952934 -0.5329200029373169 -0.9592999815940856 -1.4450000524520874 0.02219999954104424 44.579294766826536 40.0 1.0 no 6242 chrX_382407r 19292 essential YJL034W 1083 - TCTTGCAAAACCTTCTCGAC D|368|H D|368|N L|366|F silent|TTG>TTA|L|366 KAR2 KARyogamy 682.0 0 0 0 0 0.4717212713226522 P16474 0.9486550092697144 0.956179976463318 0.9587849974632264 0.0005737686879001558 0.0013708389597013593 0.0024347594007849693 -0.7695199847221375 -0.7489200234413147 4.559519767761231 2.210983991622925 45.658403717605495 45.0 1.0 no 6243 chrX_382491r 19293 essential YJL034W 1167 - TCTAACAATTGTTGGACCTT E|396|Q E|396|K L|394|F silent|TTG>TTA|L|394 KAR2 KARyogamy 682.0 0 0 0 0 -1.014984363854566 P16474 0.956179976463318 0.9475290179252625 0.9587849974632264 1.0 0.9559044241905212 0.002775059081614017 -0.2682200074195862 -0.7088599801063538 0.7768599987030029 0.5032359957695007 43.23243210767964 35.0 1.0 no 6244 chrX_382554 19296 essential YJL034W 1227 + CCAGATGAAGCTGTTGCATA P|410|R P|410|L KAR2 KARyogamy 682.0 0 0 0 0 0.10797533665218327 P16474 0.9432820081710817 0.9430609941482544 0.0006818139809183776 0.0008722489001229405 2.2012200355529785 2.006119966506958 48.01780738296146 45.0 1.0 no 6245 chrX_382603r 19299 essential YJL034W 1279 - ATCTTCGACACCTTCTTCAC D|433|H D|433|N E|432|Q E|432|K KAR2 KARyogamy 682.0 0 0 0 0 0.06297870052646015 P16474 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.002602625172585249 0.1743128001689911 1.0 0.5901409983634949 49.75110949736347 45.0 1.0 no 6246 chrX_382857r 19308 essential YJL034W 1533 - TCAATTTGAGGTACACCTCT E|518|Q E|518|K KAR2 KARyogamy 682.0 0 0 0 0 -0.9441508301672544 P16474 0.956179976463318 0.9475290179252625 0.0806756243109703 0.09764734655618668 0.0024119999725371604 -1.3101600408554075 46.871080728170064 40.0 1.0 no 6247 chrX_383987r 19312 essential YJL033W 153 - TCTCTTAAACCTTTTAATGT R|57|T R|57|K E|58|Q E|58|K HCA4 Helicase CA 770.0 0 1 0 0 0.5284219659054057 P20448 0.1751500368118286 1.0 0.5716676115989685 0.9568514227867126 38.92448061333204 25.0 1.0 no 6248 chrX_384015r 19313 essential YJL033W 181 - GATCTCAGTAAGTTTTATAA E|66|D silent|GAG>GAA|E|66 E|66|Q E|66|K HCA4 Helicase CA 770.0 0 0 0 0 0.12075568602110673 P20448 0.986855447292328 0.18126454949378967 0.15774232149124146 36.35601968720864 25.0 1.0 no 6249 chrX_383988r 19314 essential YJL033W 154 - TTCTCTTAAACCTTTTAATG E|58|Q E|58|K R|57|T R|57|K HCA4 Helicase CA 770.0 0 1 0 0 0.5014553793483539 P20448 0.5716676115989685 0.9568514227867126 0.1751500368118286 1.0 36.84535841308423 25.0 1.0 no 6250 chrX_384047 19316 essential YJL033W 210 + TCTATTCCCGTGTCCCTGCA S|71|C S|71|F P|73|A P|73|S HCA4 Helicase CA 770.0 0 0 0 0 0.9526450027779876 P20448 0.0950959250330925 0.010616058483719826 0.030232364311814305 0.11257361620664597 61.92956533552393 55.00000000000001 1.0 no 6251 chrX_384061r 19319 essential YJL033W 227 - CCAATACATCATGACCTTGC L|82|F silent|TTG>TTA|L|82 V|81|L V|81|I HCA4 Helicase CA 770.0 0 0 0 0 -1.4451405170251619 P20448 0.009337997063994408 0.12789170444011688 0.7679353952407837 47.422263000094866 45.0 1.0 no 6252 chrX_384162r 19321 essential YJL033W 328 - GGCACCTAACCCATCGAATT A|116|P A|116|T G|115|A G|115|D HCA4 Helicase CA 770.0 0 0 0 0 -0.6142234602037143 P20448 0.0 0.0 0.08889847248792647 0.0036151774693280463 51.40412582350962 50.0 1.0 no 6253 chrX_384317 19326 essential YJL033W 480 + TCAAGGATTAACATTCTTAT S|161|* S|161|L HCA4 Helicase CA 770.0 0 0 0 0 -2.4741756130495847 P20448 0.6422609686851501 36.43140806406189 25.0 1.0 yes 6254 chrX_384300 19328 essential YJL033W 463 + TCGAACTAGAAAGGATATCA F|155|L silent|TTC>TTT|F|155 L|157|V silent|CTA>TTA|L|157 HCA4 Helicase CA 770.0 0 0 0 0 -0.13713301827626878 P20448 0.662219762802124 0.07725811749696733 -0.2628200054168701 1.0238200426101685 36.98906267061813 35.0 1.0 no 6255 chrX_384570r 19332 essential YJL033W 736 - CATCACATCATGTGTACCAA silent|GTG>GTC|V|251 silent|GTG>GTA|V|251 V|251|L V|251|M HCA4 Helicase CA 770.0 0 0 0 0 0.26605957835247884 P20448 0.32479313015937805 0.10913392901420592 45.43634709673593 40.0 1.0 no 6256 chrX_384640 19336 essential YJL033W 803 + ATTCTACATTGAAGTTCCTT F|269|L silent|TTC>TTT|F|269 Y|270|* silent|TAC>TAT|Y|270 HCA4 Helicase CA 770.0 0 0 0 0 0.34138555762823897 P20448 0.3353342115879059 43.13834257169315 30.0 1.0 no 6257 chrX_384823 19337 essential YJL033W 986 + ACGTGCTAGGACAGAAACTT R|330|G R|330|C A|331|G A|331|V HCA4 Helicase CA 770.0 0 0 0 0 0.18010199810976074 P20448 0.4242224097251892 0.08367393165826797 0.26615840196609497 0.1814906746149063 0.12849999964237213 -0.09620000422000884 44.5231137362959 45.0 1.0 no 6258 chrX_384907 19338 essential YJL033W 1070 + TGACTTTCCTGCAGTCGATT D|358|E silent|GAC>GAT|D|358 HCA4 Helicase CA 770.0 0 0 0 0 1.3497653015492328 P20448 0.0 51.1928928846877 45.0 1.0 no 6259 chrX_385268 19345 essential YJL033W 1431 + GCTTATTCTCTTGGTTTACC A|478|G A|478|V HCA4 Helicase CA 770.0 0 0 0 0 0.06662783123407799 P20448 0.0 0.0 50.119907490764895 40.0 1.0 no 6260 chrX_385323r 19346 essential YJL033W 1489 - TCTTTCTTTGGCCTGCTCAA R|503|T R|503|K E|502|Q E|502|K HCA4 Helicase CA 770.0 0 0 0 0 -0.4217332935674342 P20448 0.4471481144428253 1.0 0.5684584975242615 0.8377771377563477 54.1864783365773 45.0 1.0 no 6261 chrX_385480 19347 essential YJL033W 1643 + ACACTATTTGAATATAACGA H|549|Q silent|CAC>CAT|H|549 H|549|D H|549|Y HCA4 Helicase CA 770.0 0 0 0 0 0.12500931396372267 P20448 0.010277352295815943 0.08528734743595122 0.005141031462699175 34.095882167063515 25.0 1.0 no 6262 chrX_386515 19349 essential YJL031C 706 - GCACCAAATATTTTGCTTCC W|241|C W|241|* C|242|S C|242|Y BET4 Blocked Early in Transport 327.0 0 0 0 0 0.2733868184873526 Q00618 0.35920488834381104 0.8222854733467102 -0.5663999915122986 -0.3646000027656555 47.39616315970039 40.0 0.0 no 6263 chrX_386580 19353 essential YJL031C 641 - TCAAGTCTTTCAACATTTTA L|220|F silent|TTG>TTA|L|220 D|219|H D|219|N BET4 Blocked Early in Transport 327.0 0 0 0 0 0.40632179181113415 Q00618 38.485332049205105 25.0 0.0 no 6264 chrX_386797r 19357 essential YJL031C 421 + ACATTTCAAATTATTCTGCA N|141|K silent|AAC>AAT|N|141 S|143|* S|143|L BET4 Blocked Early in Transport 327.0 0 0 0 0 0.9436389630533534 Q00618 0.0 38.57319147963523 25.0 0.0 no 6265 chrX_386856r 19358 essential YJL031C 362 + CACTAATAAAAGTCTTGACA T|122|S T|122|I BET4 Blocked Early in Transport 327.0 0 0 0 0 -0.9085229742849172 Q00618 34.82438987655462 30.0 0.0 no 6266 chrX_386917r 19360 essential YJL031C 301 + ATGCAAGAAATTACCACGGA A|102|G A|102|V BET4 Blocked Early in Transport 327.0 0 0 0 0 -0.3193887089352832 Q00618 41.830017698312304 40.0 0.0 no 6267 chrX_386946r 19361 essential YJL031C 272 + TGCTGTCGTGAATAAGTTAT A|92|G A|92|V silent|GTC>GTG|V|93 silent|GTC>GTT|V|93 BET4 Blocked Early in Transport 327.0 0 0 0 0 1.7108125139172747 Q00618 41.840234056115264 35.0 0.0 no 6268 chrX_386970 19362 essential YJL031C 251 - GTTCAGTTTGCCACACTTTA E|90|Q E|90|K BET4 Blocked Early in Transport 327.0 0 0 0 0 0.3471424843145854 Q00618 50.566801230917065 40.0 0.0 no 6269 chrX_386971 19363 essential YJL031C 250 - TTCAGTTTGCCACACTTTAG E|90|Q E|90|K BET4 Blocked Early in Transport 327.0 0 0 0 0 -1.7490753800588883 Q00618 47.900631468541405 40.0 0.0 no 6270 chrX_387031 19366 essential YJL031C 190 - ATTCCATATCCAATAGACTT W|69|C W|69|* W|69|S W|69|* BET4 Blocked Early in Transport 327.0 0 0 0 0 -2.524588783009352 Q00618 42.951301690272096 30.0 0.0 yes 6271 chrX_387142r 19367 essential YJL031C 76 + ATGCTATTTGGAATTACAGA A|27|G A|27|V BET4 Blocked Early in Transport 327.0 0 0 0 0 0.3322606550571924 Q00618 39.50562903353693 30.0 0.0 no 6272 chrX_392598r 19371 essential YJL026W 197 - CCATTTCCTTAAGTTTGTGA M|72|I M|72|I E|71|Q E|71|K RNR2 RiboNucleotide Reductase 399.0 0 1 0 0 0.7673531711740793 P09938 0.9553959965705872 0.9553959965705872 0.956179976463318 0.9475290179252625 0.36362025141716 0.36362025141716 0.3541235029697418 0.4504124224185944 0.7351999878883362 0.7351999878883362 -0.5156999826431274 -0.6507999897003174 46.584397080615425 35.0 1.0 no 6273 chrX_392760r 19374 essential YJL026W 359 - TCATTCTGTTGTTCCAGTCA M|126|I M|126|I R|125|T R|125|K RNR2 RiboNucleotide Reductase 399.0 0 0 0 0 0.06810988371294285 P09938 0.9553959965705872 0.9553959965705872 0.932735025882721 0.955805003643036 0.06044670194387436 0.06044670194387436 0.07454288750886917 1.0 1.620319962501526 1.620319962501526 1.7880799770355225 0.13447999954223633 5.3424601554870605 5.3424601554870605 51.9567905345076 40.0 1.0 no 6274 chrX_392818 19375 essential YJL026W 414 + GCCTTTTTCGCCGCTTCTGA silent|GCC>GCG|A|139 silent|GCC>GCT|A|139 A|139|G A|139|V RNR2 RiboNucleotide Reductase 399.0 0 0 0 0 -0.07988764806101427 P09938 0.9484469890594482 0.9504740238189696 0.09058400243520737 0.0056549450382590285 2.172260046005249 -0.4783599972724914 59.737035144362714 55.00000000000001 1.0 no 6275 chrX_392890r 19381 essential YJL026W 489 - CCGTAGAAACTCTTTGCCTC G|170|R G|170|S RNR2 RiboNucleotide Reductase 399.0 0 0 0 0 0.35831373417850704 P09938 0.941340982913971 0.951104998588562 0.003014823887497187 0.17577621340751648 -0.8337000012397766 0.11466000229120255 -0.9744000434875488 -0.031333327293396 50.15968290564285 50.0 1.0 no 6276 chrX_393013 19383 essential YJL026W 609 + ATTCACACCATCCCAGAAAT H|205|D H|205|Y H|205|Q silent|CAC>CAT|H|205 RNR2 RiboNucleotide Reductase 399.0 0 0 0 0 0.0433827985230103 P09938 0.9473130106925964 0.9489949941635132 0.9588389992713928 0.3395557701587677 0.008170804940164091 0.2243974357843399 1.2775399684906006 -0.07287999987602234 0.3555999994277954 0.016279999166727066 -0.4611600041389465 -0.2296800017356873 0.22386665642261505 -0.4823333323001862 -0.3957333564758301 47.13845384392084 40.0 1.0 no 6277 chrX_393020r 19384 essential YJL026W 619 - CTTCTCACCGATTTCTGGGA E|212|D silent|GAG>GAA|E|212 E|212|Q E|212|K RNR2 RiboNucleotide Reductase 399.0 0 0 0 0 0.2494368828856481 P09938 0.94931298494339 0.956179976463318 0.9475290179252625 0.16367550194263458 0.08696756511926651 1.0 1.6158200502395632 -0.4424999952316284 0.2251800000667572 52.45125878414405 50.0 1.0 no 6278 chrX_393025r 19386 essential YJL026W 624 - TCGGCCTTCTCACCGATTTC E|215|Q E|215|K A|214|P A|214|T RNR2 RiboNucleotide Reductase 399.0 0 0 0 0 0.9813872723129012 P09938 0.956179976463318 0.9475290179252625 0.9573720097541808 0.9523990154266356 0.5731791853904724 0.28278791904449463 0.011493617668747902 0.008293123915791513 -0.23673999309539795 -0.03805999830365181 6.05210018157959 0.3702600002288817 56.418596177956715 55.00000000000001 1.0 no 6279 chrX_393044r 19389 essential YJL026W 643 - AATCCATCTTAAAGCCCATT W|220|C W|220|* W|220|S W|220|* RNR2 RiboNucleotide Reductase 399.0 0 0 0 0 0.19790956475315885 P09938 0.8858469724655151 0.8858469724655151 0.0012381906853988767 0.003909830469638109 4.792019844055176 6.0722999572753915 46.14744853602997 35.0 1.0 no 6280 chrX_393080r 19390 essential YJL026W 679 - AACTAGTCTTTCACCAAACA V|233|L V|233|I RNR2 RiboNucleotide Reductase 399.0 0 0 0 0 -0.13487173872479286 P09938 0.9539830088615416 0.9574310183525084 0.0702267736196518 0.24002359807491305 1.2417000532150269 -0.813319981098175 42.02526042227993 35.0 1.0 no 6281 chrX_393137 19392 essential YJL026W 733 + GTTCCTTTGCCTCCATTTTC S|246|C S|246|F silent|TCC>TCG|S|246 silent|TCC>TCT|S|246 RNR2 RiboNucleotide Reductase 399.0 0 0 0 0 0.7857943766301179 P09938 0.945252001285553 0.9294660091400146 0.003562796162441373 0.035641711205244064 -1.5411200523376465 -0.9665799736976624 57.00816990197461 45.0 1.0 no 6282 chrX_393149r 19394 essential YJL026W 748 - TCTCTTTTTCAACCAGAAAA K|255|N silent|AAG>AAA|K|255 R|256|T R|256|K RNR2 RiboNucleotide Reductase 399.0 0 0 0 0 0.7970877754496475 P09938 0.9355990290641784 0.932735025882721 0.955805003643036 0.21700190007686612 0.00492735905572772 0.12577977776527405 1.0236599445343018 0.7031599879264832 -0.28496000170707697 1.2810399532318115 39.2303634306208 30.0 1.0 no 6283 chrX_393233r 19398 essential YJL026W 832 - GAACAACAAGCATGCAAAGT L|283|F silent|TTG>TTA|L|283 L|282|F silent|TTG>TTA|L|282 RNR2 RiboNucleotide Reductase 399.0 0 0 0 0 -0.4296836733667729 P09938 0.9587849974632264 0.9587849974632264 0.011704530566930773 0.034806322306394584 6.449120044708253 0.6531000137329102 0.8088600039482117 39.41452100008286 40.0 1.0 no 6284 chrX_393257r 19399 essential YJL026W 856 - GTCTGGTTTGTTCTTCAAAT D|292|H D|292|N RNR2 RiboNucleotide Reductase 399.0 0 1 0 0 -0.4280777429952778 P09938 0.9486550092697144 0.956179976463318 0.06715903431177139 0.26846009492874146 3.717839956283569 2.969899892807007 45.11507883681082 35.0 1.0 no 6285 chrX_393998 19402 essential YJL025W 31 + GTACAGACAACTGCCCCTCA T|12|R T|12|I 0 1 0 0 0.17740876678514425 P40992 0.02085491269826889 0.1640658676624298 55.6716147220302 55.00000000000001 1.0 no 6286 chrX_394004 19403 essential YJL025W 37 + ACAACTGCCCCTCACGGCTT D|13|E silent|GAC>GAT|D|13 N|14|K silent|AAC>AAT|N|14 0 1 0 0 -1.7472518183235246 P40992 0.1947573870420456 0.0 59.57577530658654 60.0 1.0 no 6287 chrX_394147 19409 essential YJL025W 180 + AATCTTACCACCAATGCCAC L|62|V L|62|F 0 0 0 0 -0.11880504748785485 P40992 0.0 0.0 48.77996331378711 45.0 1.0 no 6288 chrX_394355 19414 essential YJL025W 388 + AACATGTCGCCAAGATAATT H|131|D H|131|Y 0 0 0 0 0.3956443483197598 P40992 0.6293187737464905 0.13431231677532196 41.23585059620035 35.0 1.0 no 6289 chrX_394364r 19416 essential YJL025W 400 - TATCTTGAGCCAAATTATCT K|139|N silent|AAG>AAA|K|139 0 0 0 0 -0.16507374896721194 P40992 0.17278288304805756 41.310125213043754 30.0 1.0 no 6290 chrX_394615 19422 essential YJL025W 648 + GGCTCAATTTCACCTTTTAA silent|GGC>GGG|G|217 silent|GGC>GGT|G|217 S|218|* S|218|L 0 0 0 0 0.5985960493168887 P40992 0.01840970292687416 45.487889494222316 35.0 1.0 no 6291 chrX_394696 19426 essential YJL025W 729 + AACTCTGAAATTTCGTGTCA N|244|K silent|AAC>AAT|N|244 S|245|C S|245|F 0 0 0 0 0.3209674582549516 P40992 0.13388730585575104 0.12759239971637726 0.1620904803276062 41.09460664610555 35.0 1.0 no 6292 chrX_394805 19427 essential YJL025W 838 + ACATTCGGAACCTGACACTG D|280|E silent|GAC>GAT|D|280 R|282|G R|282|W 0 0 0 0 -0.4247694200126793 P40992 0.042717911303043365 0.3810551166534424 0.01931793615221977 46.71566872627238 50.0 1.0 no 6293 chrX_395051 19437 essential YJL025W 1084 + CTTCTAGTGATTATTTCCAG S|363|C S|363|F 0 0 0 0 -0.6349893290220817 P40992 0.04202787950634957 0.029946638271212574 43.715888150889676 35.0 1.0 no 6294 chrX_395088r 19438 essential YJL025W 1124 - CCATCCACTTCAAAAACTCT M|381|I M|381|I W|380|C W|380|* 0 0 0 0 1.0615628875359735 P40992 0.8924399018287659 0.8924399018287659 0.0 44.34193383203552 40.0 1.0 no 6295 chrX_403176r 19446 essential YJL019W 282 - TGTCCATTATCCTCAATGTA G|100|A G|100|E G|100|R G|100|R MPS3 MonoPolar Spindle 682.0 0 0 0 0 0.0850403386208656 P47069 0.9499930143356324 0.9438679814338684 0.941340982913971 0.941340982913971 0.3658573031425476 1.0 0.1968279629945755 0.1968279629945755 47.01540890420728 35.0 1.0 no 6296 chrX_403270r 19449 essential YJL019W 376 - ACTTTCCAAATCGTAGCTGT S|132|T S|132|N E|131|Q E|131|K MPS3 MonoPolar Spindle 682.0 0 0 0 0 -0.5663120885133819 P47069 0.9512869715690612 0.9536849856376648 0.956179976463318 0.9475290179252625 0.691999614238739 0.517383873462677 0.07253045588731766 0.07461336255073547 47.3051719900061 40.0 1.0 no 6297 chrX_403449 19452 essential YJL019W 552 + TCCGGCGCTACATCCTCTCC silent|TCC>TCG|S|185 silent|TCC>TCT|S|185 S|185|C S|185|F MPS3 MonoPolar Spindle 682.0 0 0 0 0 -1.4274372894025618 P47069 0.945252001285553 0.9294660091400146 0.042590465396642685 0.03538622707128525 62.75947818904182 65.0 1.0 no 6298 chrX_403478 19455 essential YJL019W 581 + ATTCAGCAACCTACAAAAAC F|195|L silent|TTC>TTT|F|195 S|196|R silent|AGC>AGT|S|196 MPS3 MonoPolar Spindle 682.0 0 0 0 0 0.08639754408677858 P47069 0.9387490153312684 0.9417110085487366 1.0 0.5978809595108032 37.75109070455278 35.0 1.0 no 6299 chrX_403994r 19462 essential YJL019W 1100 - GCAACCTTCTGTTCATTTCT L|373|F silent|TTG>TTA|L|373 R|372|S silent|AGG>AGA|R|372 MPS3 MonoPolar Spindle 682.0 0 0 0 0 0.4753326611670697 P47069 0.9587849974632264 0.9087679982185364 0.0 0.35575684905052185 50.50346857017309 40.0 1.0 no 6300 chrX_404180r 19465 essential YJL019W 1286 - AATCTAAATCGTCCTCCCAT D|435|H D|435|N MPS3 MonoPolar Spindle 682.0 0 0 0 0 -1.1496829053191588 P47069 0.9486550092697144 0.956179976463318 0.0 0.0 47.98992251435834 40.0 1.0 no 6301 chrX_404236 19467 essential YJL019W 1339 + ACCATTTAACTTCACCAACC H|448|D H|448|Y N|447|K silent|AAC>AAT|N|447 MPS3 MonoPolar Spindle 682.0 0 0 0 0 -0.5736728205761883 P47069 0.9473130106925964 0.9489949941635132 0.9439849853515624 0.09332896023988724 0.029178703203797337 0.4517785608768463 46.32451295236138 40.0 1.0 no 6302 chrX_404250r 19468 essential YJL019W 1356 - CCACTGCCCTGTCTCCAGGT S|458|T S|458|N G|459|R G|459|R MPS3 MonoPolar Spindle 682.0 0 0 0 0 -1.3280718559114852 P47069 0.9512869715690612 0.9536849856376648 0.941340982913971 0.941340982913971 0.6829212307929993 1.0 0.04086950793862343 0.04086950793862343 66.56357418854435 65.0 1.0 no 6303 chrX_404314r 19474 essential YJL019W 1420 - CTCACATTGCCAGTAAGTTG E|480|Q E|480|K C|479|S C|479|Y MPS3 MonoPolar Spindle 682.0 0 0 0 0 -0.02499415107186496 P47069 0.956179976463318 0.9475290179252625 0.9421560168266296 0.9290120005607604 0.5679812431335449 0.8399425148963928 0.0 0.0 47.578942955379716 45.0 1.0 no 6304 chrX_404305 19475 essential YJL019W 1408 + AACAAAGCTCCTCAACTTAC Q|471|E Q|471|* MPS3 MonoPolar Spindle 682.0 0 0 0 0 0.03190421879129285 P47069 0.9590039849281312 0.7337962985038757 41.95385464495144 40.0 1.0 no 6305 chrX_404389r 19477 essential YJL019W 1495 - GCCATGCATGTACGAAATTT G|505|R G|505|S G|505|A G|505|D MPS3 MonoPolar Spindle 682.0 0 0 0 0 1.6283838461716234 P47069 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 45.25165764622046 40.0 1.0 no 6306 chrX_404388 19478 essential YJL019W 1491 + ACCAAAATTTCGTACATGCA silent|ACC>ACG|T|498 silent|ACC>ACT|T|498 T|498|S T|498|I MPS3 MonoPolar Spindle 682.0 0 0 0 0 0.21488443014887265 P47069 0.9491789937019348 0.9472420215606691 0.6508299112319946 0.33192086219787603 41.95247521800553 35.0 1.0 no 6307 chrX_407708r 19482 essential YJL014W 153 - GTCAACACAAGACCGCCCAT L|57|F silent|TTG>TTA|L|57 silent|GTG>GTC|V|56 silent|GTG>GTA|V|56 CCT3 Chaperonin Containing TCP-1 534.0 0 0 0 0 -2.3675944376965194 P39077 0.9587849974632264 0.03087354265153408 -0.4923999905586242 0.477400004863739 53.03440445433364 55.00000000000001 1.0 yes 6308 chrX_407733 19484 essential YJL014W 175 + ACGATGGCCACGCTATTTTA N|59|K silent|AAC>AAT|N|59 CCT3 Chaperonin Containing TCP-1 534.0 0 0 0 0 -0.28913077860824604 P39077 0.9439849853515624 0.003751568263396621 1.6288000345230105 49.72783647035203 45.0 1.0 no 6309 chrX_407803r 19485 essential YJL014W 248 - CAACCTCTTCGTCTTGAGTA V|89|L V|89|I E|88|D silent|GAG>GAA|E|88 CCT3 Chaperonin Containing TCP-1 534.0 0 0 0 0 -2.860147920064442 P39077 0.9539830088615416 0.9574310183525084 0.94931298494339 0.028563208878040317 0.10496628284454346 0.01397471595555544 1.7064000368118286 1.590999960899353 0.2804000079631805 49.33040015794262 45.0 1.0 yes 6310 chrX_407837 19486 essential YJL014W 279 + ACAACAGTTATTATTCTAGC T|94|R T|94|I T|95|R T|95|I CCT3 Chaperonin Containing TCP-1 534.0 0 0 0 0 0.6574680665388868 P39077 0.9476869702339172 0.9472420215606691 0.9476869702339172 0.9472420215606691 0.0 0.0 0.0032743702176958323 0.003106799442321062 -0.6959999799728394 0.4185999929904938 0.6764000058174133 -0.5759999752044678 39.20562904674455 30.0 1.0 no 6311 chrX_407923r 19487 essential YJL014W 368 - TCAGTGCTTTCTTCAAGGCT silent|CTG>CTC|L|129 silent|CTG>CTA|L|129 A|128|P A|128|T CCT3 Chaperonin Containing TCP-1 534.0 0 0 0 0 0.5832793288046791 P39077 0.9573720097541808 0.9523990154266356 0.012980727478861807 0.017545983195304867 7.303800106048584 3.9514000415802 52.527923701989266 45.0 1.0 no 6312 chrX_407928r 19488 essential YJL014W 373 - ATCAGTCAGTGCTTTCTTCA D|131|H D|131|N silent|CTG>CTC|L|129 silent|CTG>CTA|L|129 CCT3 Chaperonin Containing TCP-1 534.0 0 1 0 0 0.13370150321160745 P39077 0.9486550092697144 0.956179976463318 0.07013066858053207 0.13921476900577545 0.903599977493286 0.7832000255584717 51.17091569801517 40.0 1.0 no 6313 chrX_407981r 19489 essential YJL014W 426 - GCATCATTTTCCACATCGAC A|149|P A|149|T D|148|H D|148|N CCT3 Chaperonin Containing TCP-1 534.0 0 0 0 0 0.4690048396259555 P39077 0.9573720097541808 0.9523990154266356 0.9486550092697144 0.956179976463318 0.07305431365966797 0.1520576924085617 0.16651231050491333 0.4234336912631989 0.671999990940094 0.4697999954223633 1.2843999862670898 1.0424000024795532 48.9764752480744 45.0 1.0 no 6314 chrX_408036 19490 essential YJL014W 478 + GTACTAAATATGTCATACAT T|161|S T|161|I CCT3 Chaperonin Containing TCP-1 534.0 0 0 0 0 0.191228105522952 P39077 0.9491789937019348 0.9472420215606691 0.19135987758636475 0.005208517890423536 -1.434399962425232 2.509999990463257 35.33903794610443 25.0 1.0 no 6315 chrX_408199 19493 essential YJL014W 641 + TCTAGATTCTCGCGTCTTAA L|215|V silent|CTA>TTA|L|215 CCT3 Chaperonin Containing TCP-1 534.0 0 0 0 0 0.006993962921941489 P39077 0.9512209892272948 0.01571105793118477 0.6633999943733215 1.7273999452590942 46.44081768762374 40.0 1.0 no 6316 chrX_408262r 19494 essential YJL014W 707 - CACGTGGATTCTCTATGTGA R|242|P R|242|H CCT3 Chaperonin Containing TCP-1 534.0 0 0 0 0 -0.4284822486276131 P39077 0.9099509716033936 0.9570810198783876 0.0029905461706221104 0.003392460756003857 2.795399904251098 -0.17180000245571134 47.434632733201674 45.0 1.0 no 6317 chrX_408683 19505 essential YJL014W 1125 + GCTTGTACCATAATGTTACG A|376|G A|376|V CCT3 Chaperonin Containing TCP-1 534.0 0 1 0 0 0.16991550472762298 P39077 0.9484469890594482 0.9504740238189696 0.05904744565486907 0.003574158996343613 1.3741999864578247 3.1142001152038574 44.35573181293438 40.0 1.0 no 6318 chrX_414545r 19509 essential YJL011C 203 + AAACAAAAACTTTATCAACC N|69|K silent|AAC>AAT|N|69 RPC17 RNA Polymerase C 161.0 0 0 0 0 0.8210098289399685 P47076 0.7539493441581726 31.43569769506666 25.0 0.0 no 6319 chrX_414601r 19510 essential YJL011C 147 + TACAATCATCCTGAATTGCA Y|50|* silent|TAC>TAT|Y|50 H|52|D H|52|Y RPC17 RNA Polymerase C 161.0 0 0 0 0 -0.3315817389371381 P47076 0.3691421151161194 1.0 -0.6685199737548828 0.022579999640583992 42.8246720250341 35.0 0.0 no 6320 chrX_414683r 19515 essential YJL011C 65 + TCTAGAAAAAAAACATCTTT L|23|V silent|CTA>TTA|L|23 RPC17 RNA Polymerase C 161.0 0 0 0 0 -0.20965376377539488 P47076 0.05629098042845726 1.6787400245666504 29.13255609804355 20.0 0.0 no 6321 chrX_418103 19516 essential YJL010C 1440 - CGTCTTCTTTCTTCTGCTGT R|486|T R|486|K R|485|T R|485|K NOP9 NucleOlar Protein 666.0 0 0 0 0 0.7878863334728438 P47077 0.07617318630218506 0.5866909623146057 0.10115792602300644 0.2945684492588043 54.10758591643696 45.0 0.0 no 6322 chrX_418117 19517 essential YJL010C 1426 - TGCTGTTGGCCAGTCATCTC A|482|P A|482|T NOP9 NucleOlar Protein 666.0 0 0 0 0 -2.286689797294025 P47077 0.2941778004169464 0.4774361252784729 58.59611645902339 55.00000000000001 0.0 yes 6323 chrX_418187 19518 essential YJL010C 1356 - TTCTTTGCATCAGACTTTTC K|458|N silent|AAG>AAA|K|458 NOP9 NucleOlar Protein 666.0 0 0 0 0 1.0855562813454414 P47077 0.549735426902771 45.43656694234829 35.0 0.0 no 6324 chrX_418465 19521 essential YJL010C 1078 - TCTTTCAACATATTTTAGCC R|366|T R|366|K E|365|Q E|365|K NOP9 NucleOlar Protein 666.0 0 0 0 0 1.6017414256626692 P47077 0.0 0.0 0.08699972182512282 0.09537909924983977 42.26714080411949 30.0 0.0 no 6325 chrX_418505 19522 essential YJL010C 1038 - TCTAAGAAATGAGAACCGAC E|353|Q E|353|K NOP9 NucleOlar Protein 666.0 0 0 0 0 0.6066910389135866 P47077 0.2566393315792084 0.02756559103727341 37.19833644277094 40.0 0.0 no 6326 chrX_418628r 19526 essential YJL010C 912 + CAGCTCATTATTCAAGTCGA L|306|V L|306|F silent|CTC>CTG|L|306 silent|CTC>CTT|L|306 NOP9 NucleOlar Protein 666.0 0 0 0 0 0.37048190442250506 P47077 0.0 0.0 45.11972172643749 40.0 0.0 no 6327 chrX_418947 19527 essential YJL010C 596 - AAACATGTGATGCATACTGA V|205|L V|205|I NOP9 NucleOlar Protein 666.0 0 0 0 0 0.34418305552772377 P47077 0.03794977813959122 0.0626867339015007 39.74684069178301 35.0 0.0 no 6328 chrX_419233 19529 essential YJL010C 310 - CATCAATTTCGAAGTTATTT L|109|F silent|TTG>TTA|L|109 NOP9 NucleOlar Protein 666.0 0 0 0 0 0.5851924160253615 P47077 0.0 36.77090413544767 25.0 0.0 no 6329 chrX_420365 19538 essential YJL008C 1279 - CCTAGAAATCAATTCAATTT R|433|T R|433|K CCT8 Chaperonin Containing TCP-1 568.0 0 0 0 0 0.2317427057396649 P47079 0.01722436398267746 0.20961427688598636 1.6266000270843506 -0.5979999899864197 35.590545127633675 25.0 0.0 no 6330 chrX_420402 19540 essential YJL008C 1242 - GGCAACAACTTACCGCCTGA L|420|F silent|TTG>TTA|L|420 L|419|F silent|TTG>TTA|L|419 CCT8 Chaperonin Containing TCP-1 568.0 0 1 0 0 -2.8035870962876612 P47079 0.006889432668685913 0.2859881222248077 3.8081998825073238 6.458799839019775 52.44929285485971 55.00000000000001 0.0 yes 6331 chrX_420422 19542 essential YJL008C 1222 - TGGCTTCATTAGTCCCTTGA K|413|N silent|AAG>AAA|K|413 M|412|I M|412|I CCT8 Chaperonin Containing TCP-1 568.0 0 0 0 0 -3.8818532961705774 P47079 0.007471745368093251 0.5209182500839233 0.5209182500839233 -0.4907999932765961 2.559400081634521 2.559400081634521 54.29864992711708 45.0 0.0 yes 6332 chrX_420629 19550 essential YJL008C 1015 - ACCTAATCTAGGCAATGGAG G|345|R G|345|S G|345|A G|345|D CCT8 Chaperonin Containing TCP-1 568.0 0 0 0 0 -4.626755166172401 P47079 0.17128412425518036 0.489152580499649 0.2481961101293564 0.44143468141555786 2.3977999687194824 3.5708000659942627 3.2000000476837163 4.491399765014648 45.055083494535104 45.0 0.0 yes 6333 chrX_420672 19552 essential YJL008C 972 - CTTCTTAATTCGAATTTGCT R|330|T R|330|K CCT8 Chaperonin Containing TCP-1 568.0 0 1 0 0 0.3733994273899141 P47079 0.004052152391523123 0.024760527536273003 0.3508000075817108 -0.1316000074148178 40.56149729205527 30.0 0.0 no 6334 chrX_420697r 19553 essential YJL008C 944 + ATACGGTATACTAGTCTTGA Y|316|* silent|TAC>TAT|Y|316 CCT8 Chaperonin Containing TCP-1 568.0 0 0 0 0 0.059990610470240076 P47079 42.657918287423634 35.0 0.0 no 6335 chrX_420785 19555 essential YJL008C 859 - GTCGGCAATCTCTTTCATCA D|293|H D|293|N A|292|P A|292|T CCT8 Chaperonin Containing TCP-1 568.0 0 0 0 0 -0.9269685009124584 P47079 0.02959725446999073 0.15056726336479187 0.12387040257453917 0.28701052069664 -0.30300000309944153 -0.901799976825714 3.5885999202728267 0.39660000801086426 50.76172907324143 45.0 0.0 no 6336 chrX_420923 19558 essential YJL008C 721 - AACTTTATGCTTTTTATCTT V|247|L V|247|I CCT8 Chaperonin Containing TCP-1 568.0 0 0 0 0 0.33084276633099546 P47079 0.029079144820570942 0.5110549926757812 -1.7115999460220337 -1.4658000469207764 38.77737371656383 20.0 0.0 no 6337 chrX_420990r 19559 essential YJL008C 651 + TCCAATTCTACCGTCATCAA silent|TCC>TCG|S|218 silent|TCC>TCT|S|218 S|218|C S|218|F CCT8 Chaperonin Containing TCP-1 568.0 0 0 0 0 0.22402880108751816 P47079 0.12280938774347305 0.35566046833992004 0.0982000008225441 -0.3106000125408173 47.32642177104077 40.0 0.0 no 6338 chrX_421074r 19564 essential YJL008C 567 + TTACCAGTTGCTCAGCAAGC P|191|A P|191|S P|191|R P|191|L CCT8 Chaperonin Containing TCP-1 568.0 0 0 0 0 0.06444809001866869 P47079 0.0 0.0 0.0 0.0 1.2330000400543213 1.4672000408172607 1.2640000581741333 -0.0130000002682209 52.68039379423573 50.0 0.0 no 6339 chrX_421139 19566 essential YJL008C 505 - TTCAGATCCGTACTTTTTGG E|175|Q E|175|K CCT8 Chaperonin Containing TCP-1 568.0 0 0 0 0 -0.6241318040736417 P47079 0.007903857156634329 0.006127249449491501 0.3107999861240387 0.05400000140070915 46.815104520507994 40.0 0.0 no 6340 chrX_421146r 19567 essential YJL008C 495 + GTCATCTCCTCCAAAAAGTA silent|GTC>GTG|V|166 silent|GTC>GTT|V|166 I|167|M silent|ATC>ATT|I|167 CCT8 Chaperonin Containing TCP-1 568.0 0 0 0 0 0.25708250271987154 P47079 0.004881720989942551 -1.9184000492095947 45.55383522284735 40.0 0.0 no 6341 chrX_421259r 19569 essential YJL008C 382 + TTCAAGGTTATAATATGGCA Q|129|E Q|129|* CCT8 Chaperonin Containing TCP-1 568.0 0 0 0 0 -1.0807234648752306 P47079 1.0 0.3930000066757202 39.689741868323146 30.0 0.0 no 6342 chrX_421459r 19571 essential YJL008C 182 + AATCATTATTACCAACGACG I|62|M silent|ATC>ATT|I|62 CCT8 Chaperonin Containing TCP-1 568.0 0 0 0 0 0.0843981384315195 P47079 0.16051138937473294 -0.7166000008583069 38.85162824657107 35.0 0.0 no 6343 chrX_421629r 19576 essential YJL008C 12 + TTGCCACAAAATCCCAACGC P|6|A P|6|S P|6|R P|6|L CCT8 Chaperonin Containing TCP-1 568.0 0 1 0 0 -2.534197194949664 P47079 0.18329422175884247 0.13519372045993805 0.618639349937439 0.1447468400001526 48.57497268794612 50.0 0.0 yes 6344 chrX_425446 19580 essential YJL005W 289 + CGACAGAACCGAAAATCAAA T|98|R T|98|I CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 0.7414882488189933 P08678 36.526152239979695 40.0 1.0 no 6345 chrX_425589 19582 essential YJL005W 432 + TCTACTCATAACCATCATGA S|145|C S|145|F T|146|S T|146|I CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 0.08682551501166877 P08678 43.06808389897867 35.0 1.0 no 6346 chrX_425671r 19587 essential YJL005W 517 - CCCTGAAAACCTTTTGAATA G|179|R G|179|R G|179|A G|179|E CYR1 CYclic AMP Requirement 2026.0 0 1 0 0 -0.7432522544728903 P08678 41.78644552545819 35.0 1.0 no 6347 chrX_426107r 19598 essential YJL005W 953 - AAACATTAGATACGTTATGT V|324|L V|324|I CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 0.030374197726445562 P08678 0.6977882385253906 0.4504441916942597 35.19161073023474 25.0 1.0 no 6348 chrX_426379 19599 essential YJL005W 1222 + CTACACTAAATTCTACACAC T|409|R T|409|I L|410|V silent|CTA>TTA|L|410 CYR1 CYclic AMP Requirement 2026.0 0 1 0 0 -0.28887737553066284 P08678 0.21224600076675412 0.0945267304778099 0.3147764503955841 37.63751847065868 35.0 1.0 no 6349 chrX_426418r 19601 essential YJL005W 1264 - TTCAGGCATGATCACCGTTT E|428|Q E|428|K M|426|I M|426|I CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 0.13732446601037618 P08678 0.5523665547370911 0.989470899105072 0.393955796957016 0.393955796957016 51.26699984574532 45.0 1.0 no 6350 chrX_426444r 19603 essential YJL005W 1290 - GCCATTGACACCGACTTCCT M|436|I M|436|I A|437|P A|437|T CYR1 CYclic AMP Requirement 2026.0 0 1 0 0 -0.10126089479051514 P08678 0.4230927228927612 0.4230927228927612 0.2739102244377136 0.574918270111084 56.37167766453933 55.00000000000001 1.0 no 6351 chrX_426631 19608 essential YJL005W 1474 + AACTTGATCCCATGTCACCG L|493|V L|493|F CYR1 CYclic AMP Requirement 2026.0 0 1 0 0 -0.2373856244217287 P08678 0.4935924112796784 0.7017154097557068 51.23569964878999 50.0 1.0 no 6352 chrX_426674 19610 essential YJL005W 1517 + TCGTCATCATCACGATCGAA R|507|G R|507|C H|508|D H|508|Y CYR1 CYclic AMP Requirement 2026.0 0 1 0 0 -0.6300384164855799 P08678 0.13035802543163302 0.016040917485952374 0.1999031901359558 1.0 45.56501976713196 45.0 1.0 no 6353 chrX_426850 19613 essential YJL005W 1693 + ATGCTCCATCAAATTTAGAT A|566|G A|566|V P|567|A P|567|S CYR1 CYclic AMP Requirement 2026.0 0 1 0 0 0.4509143615390268 P08678 0.43598824739456177 0.3806332945823669 0.4206269681453705 0.484247088432312 41.38496784740681 30.0 1.0 no 6354 chrX_426956 19617 essential YJL005W 1799 + TTCGTACACTAACGCGTATA S|601|W S|601|L Y|602|* silent|TAC>TAT|Y|602 CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 0.12439811281470207 P08678 0.033707134425640106 0.14203354716300964 43.67177997874012 40.0 1.0 no 6355 chrX_427074r 19620 essential YJL005W 1920 - CCAGAACTCTGGGCACCATC G|647|R G|647|R S|645|T S|645|N CYR1 CYclic AMP Requirement 2026.0 0 1 0 0 -0.5687193164975104 P08678 0.3676346242427826 0.3676346242427826 0.5468323230743408 0.3937584459781647 55.30577693815764 60.0 1.0 no 6356 chrX_427415 19625 essential YJL005W 2258 + GTCAGACCCACTTCATATTA S|754|* S|754|L D|755|E silent|GAC>GAT|D|755 CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 -1.1872345589889584 P08678 0.26885402202606196 0.0 48.83650314812321 40.0 1.0 no 6357 chrX_427416 19626 essential YJL005W 2259 + TCAGACCCACTTCATATTAT S|754|* S|754|L D|755|E silent|GAC>GAT|D|755 CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 -1.5535260328023166 P08678 0.26885402202606196 0.0 46.20952326259442 35.0 1.0 no 6358 chrX_427634 19631 essential YJL005W 2477 + CGCAAATATATTCCTACCTC A|827|G A|827|V CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 -0.7087596990114317 P08678 0.2629148066043854 0.24607688188552854 44.69793583936313 40.0 1.0 no 6359 chrX_427791r 19633 essential YJL005W 2637 - CTCAGTTTCATGATTGAGTT silent|CTG>CTC|L|885 silent|CTG>CTA|L|885 CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 -0.09053850365235766 P08678 44.2185183873566 35.0 1.0 no 6360 chrX_427832r 19634 essential YJL005W 2678 - TTTCAAGCTCATTACATTGA E|899|Q E|899|K CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 -0.19236254594864355 P08678 0.5375824570655823 0.8287794589996338 41.212919331787475 30.0 1.0 no 6361 chrX_427856r 19636 essential YJL005W 2702 - GTTCAACAAATCCAGCCGGT E|907|Q E|907|K V|906|L V|906|I CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 0.28418290312424865 P08678 0.5421211123466492 0.9736520648002625 0.1833772510290146 0.10314181447029114 50.88903885069754 50.0 1.0 no 6362 chrX_428015r 19642 essential YJL005W 2861 - TCATCTTCGCAAGCTTTACT M|960|I M|960|I K|959|N silent|AAG>AAA|K|959 CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 -2.0469416089700703 P08678 0.20958119630813601 0.20958119630813601 0.05714889243245125 48.06154830134353 40.0 1.0 yes 6363 chrX_428074 19643 essential YJL005W 2917 + TATCGGAAATGACAGATTTG S|974|W S|974|L CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 0.9625081826531022 P08678 0.008070649579167366 0.11333873122930528 36.776044510856146 35.0 1.0 no 6364 chrX_428282 19644 essential YJL005W 3125 + GACAAGTTTGACGTTGAACA T|1043|R T|1043|I CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 0.2156509713400329 P08678 0.004279537126421928 0.004733203444629908 41.05797480603167 40.0 1.0 no 6365 chrX_428394r 19647 essential YJL005W 3240 - GTCAACTTGGATATCTCCTG L|1086|F silent|TTG>TTA|L|1086 K|1085|N silent|AAG>AAA|K|1085 CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 -0.5042505438246592 P08678 0.0 0.4762924313545227 47.62461141879368 45.0 1.0 no 6366 chrX_428503 19649 essential YJL005W 3346 + ATCTACATTCTAACAACATA L|1117|V silent|CTA>TTA|L|1117 H|1118|D H|1118|Y CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 1.2392986489784814 P08678 0.31634265184402466 0.06500692665576935 0.012924663722515106 35.86834544861261 25.0 1.0 no 6367 chrX_428504 19650 essential YJL005W 3347 + TCTACATTCTAACAACATAA L|1117|V silent|CTA>TTA|L|1117 H|1118|D H|1118|Y CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 -0.029908454096912236 P08678 0.31634265184402466 0.06500692665576935 0.012924663722515106 34.62612703933979 25.0 1.0 no 6368 chrX_428974 19656 essential YJL005W 3817 + TATCAAACTATCATTACGAT S|1274|* S|1274|L CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 -0.5991756528368457 P08678 0.02302232570946217 35.12218592657848 25.0 1.0 no 6369 chrX_428983 19658 essential YJL005W 3826 + ATCATTACGATTGGAACTGG H|1277|D H|1277|Y CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 0.9037256761904232 P08678 0.09068220108747482 0.1119384989142418 41.28217589577071 40.0 1.0 no 6370 chrX_429104 19659 essential YJL005W 3947 + GACAGTATTACCTCAGTTAA T|1317|R T|1317|I CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 0.7894124770562806 P08678 0.23084212839603424 0.14152538776397705 43.05494279871385 35.0 1.0 no 6371 chrX_429114r 19661 essential YJL005W 3960 - AAACCTAGTACCTTTAACTG G|1326|A G|1326|D G|1326|R G|1326|S CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 0.15483286703916513 P08678 0.05693219974637032 0.01732420176267624 0.006115573458373547 0.12837086617946625 40.82658069772242 35.0 1.0 no 6372 chrX_429160r 19662 essential YJL005W 4006 - GACATTTTCATCCGGTACTT V|1342|L V|1342|I CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 0.023102516128132744 P08678 0.5235491394996643 0.7678509354591371 48.22635529179814 40.0 1.0 no 6373 chrX_429198 19663 essential YJL005W 4041 + ACAACTGCATCAATAATAAA T|1348|R T|1348|I T|1349|S T|1349|I CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 0.6914344010653717 P08678 0.0055046817287802705 0.008798100054264069 0.4913683831691742 0.08179270476102829 33.14905330558372 25.0 1.0 no 6374 chrX_429199 19664 essential YJL005W 4042 + CAACTGCATCAATAATAAAT T|1349|S T|1349|I A|1350|G A|1350|V CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 0.04854155832484025 P08678 0.4913683831691742 0.08179270476102829 0.6801407337188721 0.051907353103160865 32.79156002870383 25.0 1.0 no 6375 chrX_429296r 19666 essential YJL005W 4142 - AGCATTCGTCGTCATTTCCG C|1387|S C|1387|Y E|1386|Q E|1386|K CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 -0.20332799732064832 P08678 0.1217011734843254 0.05115848407149315 0.0 0.0 52.678966210162905 50.0 1.0 no 6376 chrX_429362r 19667 essential YJL005W 4208 - TAACAATTCTTGATATATTG V|1409|L V|1409|I CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 -0.5002931222427589 P08678 0.5809604525566101 0.7419532537460327 31.517005095057243 20.0 1.0 no 6377 chrX_429403 19668 essential YJL005W 4246 + TACTGATCAGACAACTGGAA L|1417|V silent|CTG>TTG|L|1417 CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 -0.9929328678611388 P08678 0.06903906166553497 40.43871801684401 40.0 1.0 no 6378 chrX_429546 19671 essential YJL005W 4389 + TCATATGCAGACTTGCTAAG S|1464|* S|1464|L CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 -3.533237916600648 P08678 0.02163257822394371 43.15118537947939 40.0 1.0 yes 6379 chrX_429603 19673 essential YJL005W 4446 + AAACTCTTCGCTGCAAATTT L|1484|V L|1484|F silent|CTC>CTG|L|1484 silent|CTC>CTT|L|1484 CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 0.4829231029235873 P08678 0.2820065021514893 0.05104956403374672 41.85368362982257 35.0 1.0 no 6380 chrX_429679 19676 essential YJL005W 4522 + AACAACATCTCCCAACAAAG Q|1509|E Q|1509|* H|1510|D H|1510|Y CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 0.4830595860000815 P08678 0.1813767701387405 0.12928536534309387 0.007738882675766945 40.329263183220924 40.0 1.0 no 6381 chrX_429690r 19677 essential YJL005W 4536 - TCGTATTCTTCCCGCTTTGT E|1519|Q E|1519|K CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 0.5444570969730367 P08678 0.18551589548587802 0.19871248304843905 55.137756500630466 45.0 1.0 no 6382 chrX_429708 19678 essential YJL005W 4551 + TACGAGAGGATCAGAATATC Y|1518|* silent|TAC>TAT|Y|1518 CYR1 CYclic AMP Requirement 2026.0 0 0 0 0 -2.2873528720299627 P08678 39.018536082752526 40.0 1.0 yes 6383 chrX_433660r 19681 essential YJL002C 969 + AGACCAAGATTCCCAATCTT P|325|A P|325|S P|325|R P|325|L OST1 OligoSaccharylTransferase 476.0 0 0 0 0 -1.437010111740349 P41543 0.9209179878234864 0.9124370217323304 0.896930992603302 0.9032179713249208 0.0 0.0 0.0 0.0 47.47500713139488 40.0 0.0 no 6384 chrX_433955r 19685 essential YJL002C 674 + CCACAATGCCCCATTGAATC H|226|Q silent|CAC>CAT|H|226 H|226|D H|226|Y OST1 OligoSaccharylTransferase 476.0 0 0 0 0 -0.6895949491577882 P41543 0.9877399802207948 0.9762660264968872 0.9764170050621032 0.02703241631388664 0.07688799500465393 0.01909494213759899 51.2526188346335 50.0 0.0 no 6385 chrX_434011 19686 essential YJL002C 621 - AATCTCGGAATATCTTCCCA R|213|T R|213|K silent|CCG>CCC|P|212 silent|CCG>CCA|P|212 OST1 OligoSaccharylTransferase 476.0 0 1 0 0 0.7068456400267304 P41543 0.955632984638214 0.9748079776763916 0.4800499975681305 0.5886332392692566 47.145168260525 40.0 0.0 no 6386 chrX_433947 19687 essential YJL002C 685 - ATTCACTACCTGATTCAATG silent|GTG>GTC|V|234 silent|GTG>GTA|V|234 V|234|L V|234|M OST1 OligoSaccharylTransferase 476.0 0 0 0 0 -0.5756918480496076 P41543 0.9693499803543092 0.9784780144691468 0.5827221274375916 0.17173731327056885 41.87326427581292 35.0 0.0 no 6387 chrX_434065 19690 essential YJL002C 567 - CCCAGTAAACTCTCGTCATT silent|CTG>CTC|L|195 silent|CTG>CTA|L|195 G|196|R G|196|R OST1 OligoSaccharylTransferase 476.0 0 0 0 0 -0.7460641471481453 P41543 0.9477360248565674 0.9477360248565674 0.11939433217048645 0.11939433217048645 49.42777191110292 45.0 0.0 no 6388 chrX_434135r 19695 essential YJL002C 494 + TTCTGCTTACGATACCAAGA S|166|C S|166|F A|167|G A|167|V OST1 OligoSaccharylTransferase 476.0 0 0 0 0 0.29283396712925697 P41543 0.9077129960060121 0.8902170062065125 0.9672009944915771 0.9664270281791688 0.0 0.0 0.282518208026886 0.6076362729072571 45.123131548376186 40.0 0.0 no 6389 chrX_434197 19696 essential YJL002C 435 - TCTGACATTCCAACGTGCTC E|152|Q E|152|K M|150|I M|150|I OST1 OligoSaccharylTransferase 476.0 0 0 0 0 0.34187655972637016 P41543 0.97645902633667 0.9644089937210084 0.983264982700348 0.983264982700348 0.16425998508930206 0.1509615182876587 0.764362633228302 0.764362633228302 50.45655368234026 50.0 0.0 no 6390 chrX_434257 19700 essential YJL002C 375 - ACTAAAGAAACTTCTTCCTG V|132|L V|132|M OST1 OligoSaccharylTransferase 476.0 0 0 0 0 -1.5421554038162737 P41543 0.9786369800567628 0.9877660274505616 0.4366389513015747 0.16628818213939667 38.69722284154585 35.0 0.0 no 6391 chrX_434273r 19702 essential YJL002C 356 + TCCAAATGCAATTTCCCCTC P|120|R P|120|L P|120|A P|120|S OST1 OligoSaccharylTransferase 476.0 0 0 0 0 0.0069829099144262646 P41543 0.9110649824142456 0.917351007461548 0.9343129992485046 0.925832986831665 0.0 0.0 0.0 0.0 51.025076347076386 45.0 0.0 no 6392 chrX_434338r 19705 essential YJL002C 291 + GCCAATTCGACTACAGCACC silent|GCC>GCG|A|98 silent|GCC>GCT|A|98 A|98|G A|98|V OST1 OligoSaccharylTransferase 476.0 0 0 0 1 -0.338385768702663 P41543 0.9672009944915771 0.9664270281791688 0.4025201499462128 0.2789449095726013 52.4801616344057 55.00000000000001 0.0 no 6393 chrX_434424 19707 essential YJL002C 208 - ACTGAAGATGCCACTCTCAA S|76|T S|76|N OST1 OligoSaccharylTransferase 476.0 0 0 0 0 0.0977688299944659 P41543 0.9762319922447203 0.98028302192688 0.520070493221283 0.4547546803951264 47.0234162177673 45.0 0.0 no 6394 chrX_434434r 19708 essential YJL002C 195 + TACTTCACAGCCTTTGAGAG Y|66|* silent|TAC>TAT|Y|66 F|67|L silent|TTC>TTT|F|67 OST1 OligoSaccharylTransferase 476.0 0 0 0 0 -1.0897930927258397 P41543 0.9677240252494812 0.04442903771996498 47.80942548159294 45.0 0.0 no 6395 chrX_434548 19709 essential YJL002C 84 - TCAACATTCTCCCAAGTCGC D|35|H D|35|N V|34|L V|34|I OST1 OligoSaccharylTransferase 476.0 0 0 0 0 -0.7230029043268559 P41543 0.9090110063552856 0.9202449917793274 0.9693499803543092 0.9770190119743348 0.06660435348749161 0.5028094053268433 0.5973279476165771 0.4413624107837677 51.52739054484374 50.0 0.0 no 6396 chrX_435180 19714 essential YJL001W 17 + GGACATCAATCGTTTGAAAA D|7|E silent|GAC>GAT|D|7 I|8|M silent|ATC>ATT|I|8 PRE3 PRoteinase yscE 215.0 0 0 0 0 0.2600990576633928 P38624 0.18546287715435028 0.4410195350646973 37.902765606862545 35.0 1.0 no 6397 chrX_435381 19715 essential YJL001W 102 + GCTGATTCACGTACCACCAC A|35|G A|35|V PRE3 PRoteinase yscE 215.0 0 0 0 0 -0.09778190197834412 P38624 0.007409675046801567 0.0029631389770656824 53.42411641494822 55.00000000000001 1.0 no 6398 chrX_435349r 19716 essential YJL001W 73 - CACACCATCCTTAAATGTCA V|31|L V|31|M G|30|A G|30|D PRE3 PRoteinase yscE 215.0 0 0 0 0 -0.5384980517522531 P38624 0.03718584030866623 0.0017564086010679605 0.015399858355522156 0.0031407945789396767 45.94457470798562 40.0 1.0 no 6399 chrX_435394r 19717 essential YJL001W 118 - AGCTATGTACGCACCAGTGG A|46|P A|46|T PRE3 PRoteinase yscE 215.0 0 0 0 0 0.029428377313884143 P38624 0.0601222962141037 0.09158734232187273 1.0545799732208252 -0.08218000084161757 53.41380785091781 55.00000000000001 1.0 no 6400 chrX_435419r 19718 essential YJL001W 143 - TCGTTAATTTATCTGTCACA silent|ACG>ACC|T|54 silent|ACG>ACA|T|54 PRE3 PRoteinase yscE 215.0 0 0 0 0 0.1252420376500692 P38624 41.419913713697326 30.0 1.0 no 6401 chrX_435503 19719 essential YJL001W 224 + CGACATTGTTCAGTACCATT D|76|E silent|GAC>GAT|D|76 PRE3 PRoteinase yscE 215.0 0 0 0 0 0.6929175825160467 P38624 0.11565946787595748 46.636106136783035 40.0 1.0 no 6402 chrX_435571r 19722 essential YJL001W 295 - ACATAATTCTTTGAACACCG C|105|S C|105|Y PRE3 PRoteinase yscE 215.0 0 0 0 0 -0.5884404166345647 P38624 0.2771848738193512 0.07774544507265091 1.4946199655532837 6.352439880371094 39.897099584838145 35.0 1.0 no 6403 chrX_435611r 19724 essential YJL001W 335 - CCACAATTATACCAGCAGTA V|118|L V|118|M silent|GTG>GTC|V|118 silent|GTG>GTA|V|118 PRE3 PRoteinase yscE 215.0 0 0 0 0 -0.1598355895703869 P38624 0.026413962244987488 0.0018474268727004528 46.36816951479625 40.0 1.0 no 6404 chrX_435720 19730 essential YJL001W 441 + TCTGGCTCTACTTTCATATA S|148|C S|148|F silent|GGC>GGG|G|149 silent|GGC>GGT|G|149 PRE3 PRoteinase yscE 215.0 0 0 0 0 -0.12759872110077486 P38624 0.0 0.0 46.22964410940051 35.0 1.0 no 6405 chrX_439132 19734 essential YJR002W 267 + CCTTCTCACAATCTCTCTGA P|90|R P|90|L S|91|C S|91|F MPP10 M Phase Phosphoproteins 593.0 0 0 0 0 -0.1215064386722031 P47083 0.9753050208091736 0.9834169745445251 0.9879119992256165 0.9685909748077391 0.4989223182201386 0.32978495955467224 0.053100936114788055 0.05054781958460808 50.33408302556643 45.0 1.0 no 6406 chrX_439161r 19737 essential YJR002W 299 - CTTCCCCGGATGATGAGTTC E|106|Q E|106|K silent|GGG>GGC|G|105 silent|GGG>GGA|G|105 MPP10 M Phase Phosphoproteins 593.0 0 1 0 0 -1.9292555241397389 P47083 1.0002599954605105 0.9889079928398132 0.25557348132133484 0.22358062863349915 54.624847609748876 55.00000000000001 1.0 no 6407 chrX_439402r 19745 essential YJR002W 540 - AACTTATCATTGATACCATA K|186|N silent|AAG>AAA|K|186 MPP10 M Phase Phosphoproteins 593.0 0 1 0 0 0.6455753244862531 P47083 0.912319004535675 0.43475487828254705 38.11940201080529 25.0 1.0 no 6408 chrX_439157 19746 essential YJR002W 292 + GCACCCTGAACTCATCATCC T|99|S T|99|I S|98|R silent|AGC>AGT|S|98 MPP10 M Phase Phosphoproteins 593.0 0 1 0 0 0.12199268916955072 P47083 0.9910879731178284 0.9891359806060792 0.973734974861145 0.7370545864105225 0.1903046518564224 0.5292857885360718 55.20813297076319 55.00000000000001 1.0 no 6409 chrX_439582r 19748 essential YJR002W 720 - TTCTTCACAGGTTCTTTTGT K|246|N silent|AAG>AAA|K|246 silent|GTG>GTC|V|245 silent|GTG>GTA|V|245 MPP10 M Phase Phosphoproteins 593.0 0 0 0 0 -1.7683856206398842 P47083 0.9806249737739564 0.4338776767253876 48.37799204023218 35.0 1.0 no 6410 chrX_439528r 19749 essential YJR002W 666 - TCCTCCTCCTCGTCATCTGA E|228|D silent|GAG>GAA|E|228 E|229|Q E|229|K MPP10 M Phase Phosphoproteins 593.0 0 0 0 0 -0.24086385043736505 P47083 0.9933249950408936 1.0004899501800537 0.9891330003738404 0.3593229353427887 0.0371604822576046 0.029107904061675068 60.7217343651912 55.00000000000001 1.0 no 6411 chrX_439667r 19751 essential YJR002W 805 - GTCTAATTTCACTTTATCCA D|275|H D|275|N MPP10 M Phase Phosphoproteins 593.0 0 0 0 0 0.5560639225867641 P47083 0.9090110063552856 0.9202449917793274 0.0 0.0 43.626051047856606 30.0 1.0 no 6412 chrX_439714r 19753 essential YJR002W 852 - TCTCCCACTCCCTCAGCATT G|290|A G|290|E E|291|Q E|291|K MPP10 M Phase Phosphoproteins 593.0 0 1 0 0 -0.7126165930812276 P47083 0.9732409715652466 0.9595270156860352 0.9840490221977234 0.972000002861023 0.6968870162963867 1.0 0.4474730789661408 0.7646392583847046 62.56827539226504 55.00000000000001 1.0 no 6413 chrX_440027 19757 essential YJR002W 1162 + ACATCACACGTAAGTCTCAA D|388|E silent|GAC>GAT|D|388 I|389|M silent|ATC>ATT|I|389 MPP10 M Phase Phosphoproteins 593.0 0 0 0 0 -0.7851022093514988 P47083 0.9707459807395936 0.9787610173225404 0.028486717492341995 0.16915847361087802 43.34217622383193 40.0 1.0 no 6414 chrX_440050r 19758 essential YJR002W 1188 - ACATCACTCAATTCAAATTG V|403|L V|403|I D|402|H D|402|N MPP10 M Phase Phosphoproteins 593.0 0 0 0 0 0.0003353747077911584 P47083 0.9693499803543092 0.9770190119743348 0.965224027633667 0.97645902633667 0.3864419758319855 0.3342932760715485 0.011780989356338978 0.02229214459657669 36.46050547397113 30.0 1.0 no 6415 chrX_440168r 19762 essential YJR002W 1306 - AGCATAAAGTTCTGATATTT A|442|P A|442|T MPP10 M Phase Phosphoproteins 593.0 0 0 0 0 0.6872752033894844 P47083 0.9770879745483398 0.9687960147857666 0.15130199491977692 0.9576585292816162 37.35030164385017 25.0 1.0 no 6416 chrX_449265r 19764 essential YJR006W 66 - ACAATTCTTACTCTCGTTCG V|29|L V|29|I R|27|T R|27|K POL31 POLymerase 487.0 0 0 0 0 0.6758901894542495 P46957 0.3994571566581726 0.2575943171977997 0.5698063373565674 0.9153227806091307 -0.4456000030040741 -0.5171999931335449 2.5826001167297363 0.02500000037252903 44.51481597178548 40.0 1.0 no 6417 chrX_449488 19771 essential YJR006W 286 + TTCAGGGAAACCAACCATGT Q|97|E Q|97|* POL31 POLymerase 487.0 0 0 0 0 -0.258279700406271 P46957 0.8733229637145996 0.2046000063419342 46.825426785580596 45.0 1.0 no 6418 chrX_449687 19773 essential YJR006W 485 + TCGGTCTACACCCTTCATCA R|163|G R|163|W S|164|C S|164|F POL31 POLymerase 487.0 0 0 0 0 -0.8505115400050631 P46957 0.3858509659767151 0.01965051144361496 0.03019842877984047 0.02824903279542923 55.237638577946605 50.0 1.0 no 6419 chrX_449746r 19777 essential YJR006W 547 - GTCTAAAACTTGAAATGTCC D|189|H D|189|N POL31 POLymerase 487.0 0 0 0 0 -1.4087007499844066 P46957 0.0 0.0 37.863628834977995 35.0 1.0 no 6420 chrX_449804r 19779 essential YJR006W 605 - GGCAGGTAGCAATTGGTGCA C|208|S C|208|Y POL31 POLymerase 487.0 0 0 0 0 -1.6730092972226582 P46957 0.7363235950469971 0.051937427371740334 1.0776000022888184 5.519199848175049 55.06458645440114 55.00000000000001 1.0 no 6421 chrX_449830r 19781 essential YJR006W 631 - AACAAGAGCAATTTTTCCCC V|217|L V|217|I POL31 POLymerase 487.0 0 0 0 0 0.6976873032963746 P46957 0.4000777900218964 0.2578369081020355 46.14744853603008 40.0 1.0 no 6422 chrX_449880r 19783 essential YJR006W 681 - TCCAATCTCAATAGCCTATC L|233|F silent|TTG>TTA|L|233 E|234|Q E|234|K POL31 POLymerase 487.0 0 0 0 0 -0.9372337104343088 P46957 0.10055947303771973 0.21083274483680725 0.1051572635769844 5.274400234222412 46.65895086187589 40.0 1.0 no 6423 chrX_450169r 19790 essential YJR006W 970 - ACCGTTGAAGTATGATTCTA G|330|R G|330|S G|330|A G|330|D POL31 POLymerase 487.0 0 0 0 0 -0.07676063136531164 P46957 0.5363858938217163 0.6543030738830566 0.7960578799247742 0.5726857781410217 42.973665480392754 35.0 1.0 no 6424 chrX_451416r 19794 essential YJR007W 399 - TGACCAAATTTTCGACTTAA G|139|A G|139|D G|139|R G|139|S SUI2 SUppressor of Initiator codon 304.0 0 1 0 0 0.7932001409177472 P20459 0.8968020081520081 0.8909209966659546 0.8869400024414062 0.904299020767212 0.1036461591720581 0.006148186512291431 0.005673221778124571 0.029427865520119667 2.7527999877929688 2.9016599655151367 2.742840051651001 2.9051198959350586 38.32864368860317 30.0 1.0 no 6425 chrX_451462r 19795 essential YJR007W 445 - CCAAACAGTTTCGTCAATGA W|155|S W|155|* V|154|L V|154|I SUI2 SUppressor of Initiator codon 304.0 0 0 0 0 0.28943624943279145 P20459 0.7755069732666016 0.9118689894676208 0.9259250164031982 0.02270866557955742 0.3028539717197418 0.24167492985725406 4.9476399421691895 -1.1474000215530396 1.5887600183486938 2.5539920330047607 -0.4591419994831085 43.02375843435596 40.0 1.0 no 6426 chrX_451463 19796 essential YJR007W 443 + CATCATTGACGAAACTGTTT I|149|M silent|ATC>ATT|I|149 SUI2 SUppressor of Initiator codon 304.0 0 0 0 0 -1.2823970634069894 P20459 0.9063839912414552 0.012895206920802591 -0.05127999931573868 -0.3169020116329193 39.75112582590697 35.0 1.0 no 6427 chrX_451540r 19797 essential YJR007W 523 - AGCTTGTGGTGTTAATCTCT A|181|P A|181|T SUI2 SUppressor of Initiator codon 304.0 0 1 0 0 0.227792426125574 P20459 0.8970440030097961 0.8906980156898499 1.0 0.10340794175863266 49.18947031724787 40.0 1.0 no 6428 chrX_451462 19798 essential YJR007W 442 + CCATCATTGACGAAACTGTT silent|TCC>TCG|S|148 silent|TCC>TCT|S|148 I|149|M silent|ATC>ATT|I|149 SUI2 SUppressor of Initiator codon 304.0 0 0 0 1 0.3162447211850258 P20459 0.9063839912414552 0.012895206920802591 -0.05127999931573868 -0.3169020116329193 43.14241260575478 40.0 1.0 no 6429 chrX_451554r 19799 essential YJR007W 537 - GCTCTAATCTTTACAGCTTG R|185|T R|185|K A|186|P A|186|T SUI2 SUppressor of Initiator codon 304.0 0 1 0 0 -0.950757510584757 P20459 0.8849449753761292 0.905120015144348 0.8500279784202576 0.8618280291557312 0.00403234688565135 0.11870872229337692 0.008082680404186249 0.007449110038578509 45.79820735226878 40.0 1.0 no 6430 chrX_452724r 19806 no_effect YJR008W 297 - TCCACTTTCAGATTACCCAA silent|GTG>GTC|V|105 silent|GTG>GTA|V|105 D|106|H D|106|N 0 0 0 0 -0.6669182110849111 P47085 0.9486550092697144 0.956179976463318 0.0 0.0 49.18313584719539 40.0 1.0 no 6431 chrX_452784r 19807 no_effect YJR008W 357 - AACAGCTTCTTTCCGTTCTC silent|CTG>CTC|L|125 silent|CTG>CTA|L|125 K|124|N silent|AAG>AAA|K|124 0 0 0 0 0.19328554794994907 P47085 0.9355990290641784 0.2715111970901489 0.397599995136261 51.4982466005796 45.0 1.0 no 6432 chrX_453018 19812 no_effect YJR008W 588 + AGCAGTGATTTCTGTCATTG S|197|R silent|AGC>AGT|S|197 0 0 0 0 -0.4894244510532091 P47085 0.9417110085487366 0.0 46.605457604911116 40.0 1.0 no 6433 chrX_453145 19815 no_effect YJR008W 715 + CACATCATCAAGTTCCCATT H|240|D H|240|Y H|241|D H|241|Y 0 0 0 0 0.7946798525470529 P47085 0.9473130106925964 0.9489949941635132 0.9473130106925964 0.9489949941635132 0.21570360660552976 0.1393621861934662 0.7055754661560059 0.3875419497489929 0.1055999994277954 -0.5803999900817871 0.46279999613761896 -0.8727999925613403 48.41493648709297 40.0 1.0 no 6434 chrX_460514 19817 essential YJR013W 132 + GCTGCTAAATATGTATACGA A|45|G A|45|V A|46|G A|46|V 0 0 0 0 -1.00494275477856 P47088 0.9484469890594482 0.9504740238189696 0.9484469890594482 0.9504740238189696 0.0 0.0 0.02336985245347023 0.0073489020578563205 40.51418278401826 35.0 1.0 no 6435 chrX_460758r 19821 essential YJR013W 379 - AGCGTTTCCCCTTGTACTGA A|133|P A|133|T 0 0 0 0 -0.41490448939034463 P47088 0.9573720097541808 0.9523990154266356 0.06662821024656296 0.0728171169757843 57.181426798588454 50.0 1.0 no 6436 chrX_461235 19830 essential YJR013W 853 + CCACATTCGATAACCTATTG T|286|R T|286|I silent|CCC>CCG|P|285 silent|CCC>CCT|P|285 0 0 0 0 -0.932124368266254 P47088 0.9476869702339172 0.9472420215606691 0.014794072136282919 0.011898852884769441 43.63986284297754 40.0 1.0 no 6437 chrX_461236 19832 essential YJR013W 854 + CACATTCGATAACCTATTGA T|286|R T|286|I F|287|L silent|TTC>TTT|F|287 0 0 0 0 -0.048760650374336106 P47088 0.9476869702339172 0.9472420215606691 0.9387490153312684 0.014794072136282919 0.011898852884769441 0.0963079184293747 41.17480485444946 35.0 1.0 no 6438 chrX_461248r 19833 essential YJR013W 869 - GCACAAATAAAACCCTCAAT V|296|L V|296|M silent|GTG>GTC|V|296 silent|GTG>GTA|V|296 0 0 0 0 0.938299458533832 P47088 0.9539830088615416 0.9587630033493042 0.6426352262496948 0.16236403584480286 39.39992709694678 35.0 1.0 no 6439 chrX_465008r 19840 essential YJR016C 1178 + GCCACTCTCCCACCCAATCA P|394|R P|394|L P|394|A P|394|S ILV3 IsoLeucine-plus-Valine requiring 585.0 0 1 0 0 -0.23112460438946925 P39522 0.005359375383704901 0.0707884132862091 0.029855577275156975 0.023658929392695427 62.147741326111934 60.0 0.0 no 6440 chrX_465083r 19842 essential YJR016C 1103 + GACTGTTACCGGTGACACTT T|369|S T|369|I ILV3 IsoLeucine-plus-Valine requiring 585.0 0 0 0 0 0.18511232065723288 P39522 0.019469739869236943 0.0025243316777050486 50.78798747927971 50.0 0.0 no 6441 chrX_465322r 19846 essential YJR016C 864 + ACTTATGTCGTTGCAACCGG T|289|S T|289|I ILV3 IsoLeucine-plus-Valine requiring 585.0 0 0 0 0 0.21642993011470685 P39522 0.29090848565101624 0.7128378748893738 49.75037622441618 50.0 0.0 no 6442 chrX_465306 19847 essential YJR016C 883 - AACAGCATTAGTGGACCCAC V|301|L V|301|I A|300|P A|300|T ILV3 IsoLeucine-plus-Valine requiring 585.0 0 0 0 0 -1.2995613592493758 P39522 0.013440501876175405 0.13542434573173526 0.01344437710940838 0.07911853492259979 50.13950764186802 50.0 0.0 no 6443 chrX_465362r 19848 essential YJR016C 824 + TCGTGATATCCTCACAAAAG R|276|G R|276|C ILV3 IsoLeucine-plus-Valine requiring 585.0 0 0 0 0 0.3537207694515776 P39522 0.00626409100368619 0.0008786274120211601 41.04892164051421 40.0 0.0 no 6444 chrX_465435 19850 essential YJR016C 754 - ACACTCAGCTAACTTCTCCT E|257|D silent|GAG>GAA|E|257 C|258|S C|258|Y ILV3 IsoLeucine-plus-Valine requiring 585.0 0 0 0 0 -3.3299547281276443 P39522 0.2403276860713959 0.029149984940886494 0.0017304191133007407 51.21529413779257 45.0 0.0 yes 6445 chrX_465625r 19860 essential YJR016C 561 + GTCTCTGCGTTCCAATCCTA silent|GTC>GTG|V|188 silent|GTC>GTT|V|188 S|189|C S|189|F ILV3 IsoLeucine-plus-Valine requiring 585.0 0 0 0 0 0.18778864774755333 P39522 0.008147096261382103 0.004950657021254301 55.9633819399079 50.0 0.0 no 6446 chrX_465709 19864 essential YJR016C 480 - CCACCATATACCATGATGGA G|166|A G|166|D G|167|R G|167|S ILV3 IsoLeucine-plus-Valine requiring 585.0 0 0 0 0 -2.9118267981393124 P39522 0.05804720520973205 0.0020143052097409964 0.0023415700998157267 0.011103248223662376 48.93370784197759 45.0 0.0 yes 6447 chrX_465719r 19867 essential YJR016C 467 + ACATAACAGACCTTCCATCA H|157|D H|157|Y N|158|K silent|AAC>AAT|N|158 ILV3 IsoLeucine-plus-Valine requiring 585.0 0 0 0 0 0.8035760435964969 P39522 0.20462356507778168 1.0 0.0040128519758582115 46.672122456907346 40.0 0.0 no 6448 chrX_465901r 19873 essential YJR016C 285 + AACACCATCGGTGTTTCAGA N|96|K silent|AAC>AAT|N|96 T|97|S T|97|I ILV3 IsoLeucine-plus-Valine requiring 585.0 0 1 0 0 0.3510159121504016 P39522 0.0601549968123436 0.1335529386997223 0.0019483509240671992 48.7463137291145 45.0 0.0 no 6449 chrX_465936 19875 essential YJR016C 253 - TTTCAAACCCGCTTTTTCAA L|90|F silent|TTG>TTA|L|90 ILV3 IsoLeucine-plus-Valine requiring 585.0 0 1 0 0 0.3290534672112093 P39522 0.17681917548179624 45.55816967155766 35.0 0.0 no 6450 chrX_465983 19878 essential YJR016C 206 - CCAATAGATGCATGTTACAT L|75|F silent|TTG>TTA|L|75 ILV3 IsoLeucine-plus-Valine requiring 585.0 0 0 0 0 0.7295682102924657 P39522 0.706981897354126 42.56638062309094 35.0 0.0 no 6451 chrX_466053 19883 essential YJR016C 136 - ATCTTCCTTCTTGAAACCGG D|52|H D|52|N E|51|Q E|51|K ILV3 IsoLeucine-plus-Valine requiring 585.0 0 1 0 0 0.4999705302267016 P39522 0.005599863827228546 0.010979318059980871 0.1561894714832306 0.10822943598031998 48.12342012786172 45.0 0.0 no 6452 chrX_466099r 19885 essential YJR016C 87 + ATCACTGAACCTAAGGGCCA I|30|M silent|ATC>ATT|I|30 T|31|S T|31|I ILV3 IsoLeucine-plus-Valine requiring 585.0 0 1 0 0 -1.0027160070764098 P39522 0.010839260183274746 0.03929989784955978 0.0109988646581769 50.814436608510675 50.0 0.0 no 6453 chrX_466676 19890 essential YJR017C 338 - AATCTGATCTCTCTTTAGCC D|119|H D|119|N ESS1 ESSential 170.0 0 0 0 0 0.08179316809859719 P22696 0.8410459756851196 0.8675090074539185 0.0 0.0 47.83452006501426 40.0 0.0 no 6454 chrX_466677 19892 essential YJR017C 337 - ATCTGATCTCTCTTTAGCCA D|119|H D|119|N ESS1 ESSential 170.0 0 0 0 0 1.1462777087364378 P22696 0.8410459756851196 0.8675090074539185 0.0 0.0 50.95829445011049 40.0 0.0 no 6455 chrX_466725 19896 essential YJR017C 289 - GTCATCCAACCTCGTGATTA D|103|H D|103|N D|102|H D|102|N ESS1 ESSential 170.0 0 1 0 0 0.4061873883853272 P22696 0.908900022506714 0.9803090095520021 0.9332820177078248 0.9899290204048156 0.10892015695571901 0.41124072670936573 0.13908115029335022 0.492218017578125 -0.08513999730348587 -0.13196000456809998 50.3196259521016 45.0 0.0 no 6456 chrX_466734r 19897 essential YJR017C 277 + AACTGAAAACCTTAATCACG L|94|V silent|CTG>TTG|L|94 ESS1 ESSential 170.0 0 0 0 0 0.6271861090119022 P22696 0.8931679725646973 0.047333087772130966 36.263097754138414 35.0 0.0 no 6457 chrX_466973 19906 essential YJR017C 41 - TACTATACCTGACGGTCCAC S|20|T S|20|N ESS1 ESSential 170.0 0 0 0 0 1.040164044416015 P22696 0.9123070240020752 0.8326470255851746 0.007415082771331072 0.0024430712219327693 50.15253488604424 50.0 0.0 no 6458 chrX_466972 19907 essential YJR017C 42 - TTACTATACCTGACGGTCCA S|20|T S|20|N ESS1 ESSential 170.0 0 0 0 0 0.5445623040739073 P22696 0.9123070240020752 0.8326470255851746 0.007415082771331072 0.0024430712219327693 49.96796799890421 45.0 0.0 no 6459 chrX_511171 19915 essential YJR041C 2573 - ACTCCAACTTGTTTTCTGTA E|864|Q E|864|K E|864|D silent|GAG>GAA|E|864 URB2 Unhealthy Ribosome Biogenesis 1174.0 0 0 0 0 0.3323081220296901 P47108 0.956179976463318 0.9475290179252625 0.94931298494339 0.3805481791496277 0.047475624829530716 0.09356027841567993 46.805775596015785 35.0 0.0 no 6460 chrX_511213 19918 essential YJR041C 2531 - TTTCCTGTTCTTCTGGCGCA E|850|Q E|850|K Q|849|H silent|CAG>CAA|Q|849 URB2 Unhealthy Ribosome Biogenesis 1174.0 0 0 0 0 -0.6281007315794613 P47108 0.956179976463318 0.9475290179252625 0.9570760130882264 0.5508952736854553 0.8534838557243347 0.05622312799096108 57.79386513438374 50.0 0.0 no 6461 chrX_511560 19920 essential YJR041C 2184 - TCTAAGAACTTCTCACTCAC E|735|Q E|735|K URB2 Unhealthy Ribosome Biogenesis 1174.0 0 0 0 0 0.3097595771886058 P47108 0.956179976463318 0.9475290179252625 0.30442315340042114 0.5709964036941528 42.261378835069024 40.0 0.0 no 6462 chrX_511831r 19927 essential YJR041C 1910 + CATCAACAAAAACGTTAGAG I|638|M silent|ATC>ATT|I|638 N|639|K silent|AAC>AAT|N|639 URB2 Unhealthy Ribosome Biogenesis 1174.0 0 0 0 0 -0.6798548132142812 P47108 0.9598389863967896 0.9439849853515624 0.05551334097981453 0.10801106691360474 33.65779759235045 35.0 0.0 no 6463 chrX_511871 19928 essential YJR041C 1873 - AATCAAAGCTTCTAGAGCGA L|630|F silent|TTG>TTA|L|630 URB2 Unhealthy Ribosome Biogenesis 1174.0 0 0 0 0 0.9516272253919952 P47108 0.9587849974632264 0.044593844562768936 42.49707663135359 40.0 0.0 no 6464 chrX_512296 19929 essential YJR041C 1448 - CTTCCATTATATGATACTTT E|489|Q E|489|K M|488|I M|488|I URB2 Unhealthy Ribosome Biogenesis 1174.0 0 0 0 0 0.3618761367318719 P47108 0.956179976463318 0.9475290179252625 0.9553959965705872 0.9553959965705872 0.09068021178245544 0.09335368126630783 0.07135943323373795 0.07135943323373795 39.9904171481607 25.0 0.0 no 6465 chrX_512453r 19933 essential YJR041C 1288 + TCAATCACGATTCCACCAAC silent|GTC>GTG|V|430 silent|GTC>GTT|V|430 H|432|D H|432|Y URB2 Unhealthy Ribosome Biogenesis 1174.0 0 0 0 0 0.9465748873174086 P47108 0.9473130106925964 0.9489949941635132 0.6247866153717041 0.17722247540950775 45.977131978595416 45.0 0.0 no 6466 chrX_512507r 19934 essential YJR041C 1234 + TCACTTTATCTTCTTTACAA T|413|S T|413|I F|412|L silent|TTC>TTT|F|412 URB2 Unhealthy Ribosome Biogenesis 1174.0 0 0 0 0 0.2676978953186301 P47108 0.9491789937019348 0.9472420215606691 0.9387490153312684 1.0 0.1440081149339676 0.7669138312339783 39.62865717203744 25.0 0.0 no 6467 chrX_512735r 19938 essential YJR041C 1006 + TTGCTATTAAACATATTTTT A|337|G A|337|V URB2 Unhealthy Ribosome Biogenesis 1174.0 0 0 0 0 0.5147790144922805 P47108 0.9484469890594482 0.9504740238189696 1.0 0.021984457969665527 33.61331900174781 15.0 0.0 no 6468 chrX_512674r 19939 essential YJR041C 1067 + TCTCTTTTCCTCTCATATTT silent|CTC>CTG|L|357 silent|CTC>CTT|L|357 L|357|V L|357|F URB2 Unhealthy Ribosome Biogenesis 1174.0 0 0 0 0 0.2346479867687716 P47108 0.9512209892272948 0.9587849974632264 0.39587441086769104 0.12788709998130798 47.58926890465085 30.0 0.0 no 6469 chrX_513576r 19945 essential YJR041C 165 + CTCATTGATAGGCTCAACAA silent|CTC>CTG|L|56 silent|CTC>CTT|L|56 URB2 Unhealthy Ribosome Biogenesis 1174.0 0 0 0 0 -0.4627104439518679 P47108 43.20725795159109 40.0 0.0 no 6470 chrX_513587r 19946 essential YJR041C 154 + TCTTAGATTTACTCATTGAT silent|GTC>GTG|V|52 silent|GTC>GTT|V|52 URB2 Unhealthy Ribosome Biogenesis 1174.0 0 0 0 0 -0.481864729258393 P47108 38.686087144624885 25.0 0.0 no 6471 chrX_513647 19947 essential YJR041C 97 - ATCAAATTTTGAAACTATCT D|39|H D|39|N URB2 Unhealthy Ribosome Biogenesis 1174.0 0 0 0 0 -0.01614554278419078 P47108 0.9486550092697144 0.956179976463318 0.01920122466981411 0.0964570939540863 32.66002027072068 20.0 0.0 no 6472 chrX_514247 19956 essential YJR042W 192 + ATGCCTTTAAAGTTCAAGCT P|66|A P|66|S P|66|R P|66|L NUP85 NUclear Pore 744.0 0 0 0 0 0.13765482965456974 P46673 0.708830714225769 0.6850314140319824 0.4749369919300079 0.2764379680156708 1.0123000144958496 1.3538000583648682 -0.0704599991440773 0.6747000217437744 44.605946500726596 35.0 1.0 no 6473 chrX_514328r 19958 essential YJR042W 276 - TCTAATCTAGGAATTCTAAC D|99|H D|99|N R|97|T R|97|K NUP85 NUclear Pore 744.0 0 0 0 0 -0.1249034852594422 P46673 0.02197928167879581 0.07705656439065932 0.7306925058364868 0.8482375741004944 3.525599956512451 2.1375799179077153 3.8063600063323975 0.9403600096702576 35.766240313440726 30.0 1.0 no 6474 chrX_514399r 19960 essential YJR042W 347 - CTCTGTCATCACCTAAATCA R|122|T R|122|K D|121|H D|121|N NUP85 NUclear Pore 744.0 0 0 0 0 0.5960684410553304 P46673 0.01273183058947325 0.1782991886138916 0.2630566358566284 0.11258243024349213 3.4989800453186035 0.5486999750137329 -0.64301997423172 -0.7755600214004517 45.76491271091454 40.0 1.0 no 6475 chrX_514494r 19963 essential YJR042W 442 - TTCATTCAGAATCGCCTCCA E|154|Q E|154|K silent|CTG>CTC|L|152 silent|CTG>CTA|L|152 NUP85 NUclear Pore 744.0 0 0 0 0 -1.3123971704861943 P46673 0.0 0.0 -0.5112000107765198 -1.2268999814987185 51.56469410753994 45.0 1.0 no 6476 chrX_515150r 19977 essential YJR042W 1098 - TCTGCTGATAGTTCTAATGA E|373|Q E|373|K A|372|P A|372|T NUP85 NUclear Pore 744.0 0 0 0 0 -2.332888238859524 P46673 0.11618317663669585 0.021829545497894287 0.22481802105903625 0.603123664855957 0.16500000655651093 0.2192800045013428 0.7648000121116638 0.2329999953508377 -0.6690999865531921 0.3251799941062927 -0.1037999987602234 -0.08406666666269302 0.5925333499908447 0.4979999959468842 42.832084846605774 35.0 1.0 yes 6477 chrX_515231 19979 essential YJR042W 1176 + CCATGCGTCGACATCATTAG P|393|R P|393|L C|394|W silent|TGC>TGT|C|394 NUP85 NUclear Pore 744.0 0 0 0 0 0.3102745957328212 P46673 0.04652804881334305 0.059342432767152786 0.004485385492444038 6.7358598709106445 2.61680006980896 25.92962074279785 48.79568431100671 50.0 1.0 no 6478 chrX_515260 19981 essential YJR042W 1205 + ACACTCAATTTTACCGGTAA H|403|Q silent|CAC>CAT|H|403 H|403|D H|403|Y NUP85 NUclear Pore 744.0 0 0 0 0 -0.1283565249459005 P46673 0.21796974539756772 0.15237301588058472 1.0 -0.5188999772071838 0.4763999879360199 -0.9282400012016296 -0.3765799999237061 -0.09994000196456908 -0.5523999929428101 -0.2635999917984009 1.135200023651123 -1.9117000102996824 42.743398225417145 35.0 1.0 no 6479 chrX_515492 19988 essential YJR042W 1437 + GAACTATGGCCCGTTGCCAT L|481|V silent|CTA>TTA|L|481 NUP85 NUclear Pore 744.0 0 0 0 0 -0.3791904091123054 P46673 0.0 2.8146800994873047 56.1907021133369 55.00000000000001 1.0 no 6480 chrX_515523r 19990 essential YJR042W 1471 - TCTCGTCCCTGTTGCAGATA silent|ACG>ACC|T|496 silent|ACG>ACA|T|496 R|497|T R|497|K NUP85 NUclear Pore 744.0 0 0 0 0 -0.21152189299866744 P46673 0.5753180384635925 0.8057571649551392 0.5856000185012817 0.006200000178068875 56.0583190007181 50.0 1.0 no 6481 chrX_515587r 19991 essential YJR042W 1535 - TGTCATCATTCGTAACAAAT D|518|H D|518|N D|517|H D|517|N NUP85 NUclear Pore 744.0 0 0 0 0 -1.0837142286219366 P46673 0.0 0.0 0.0 0.0 1.9615999460220337 2.8996000289916988 0.3106000125408173 0.27160000801086426 38.25489915800307 30.0 1.0 no 6482 chrX_515673r 19994 essential YJR042W 1621 - TAACATTTGATTACCCAACG M|546|I M|546|I NUP85 NUclear Pore 744.0 0 0 0 0 -0.4571595253695105 P46673 0.5868658423423767 0.5868658423423767 0.4002799987792969 0.4002799987792969 40.47749734059687 35.0 1.0 no 6483 chrX_520189 19998 essential YJR045C 1394 - TAACCAATTCTCTTTCACCT V|471|L V|471|I L|470|F silent|TTG>TTA|L|470 SSC1 Stress-Seventy subfamily C 654.0 0 1 0 0 0.11406233362251733 P0CS90 0.013999093323946001 0.017274364829063416 0.2252392023801804 1.3249399662017822 2.0834400653839107 1.6033400297164917 45.98791859639317 35.0 0.0 no 6484 chrX_520327 20000 essential YJR045C 1256 - TTTCGATACCTAGAGACAAT E|425|Q E|425|K SSC1 Stress-Seventy subfamily C 654.0 0 0 0 0 0.43877863574198456 P0CS90 0.0 0.0 41.10067513138398 35.0 0.0 no 6485 chrX_520239r 20002 essential YJR045C 1341 + ATCTTCTCCACTGCCGCTGC I|448|M silent|ATC>ATT|I|448 F|449|L silent|TTC>TTT|F|449 SSC1 Stress-Seventy subfamily C 654.0 0 1 0 0 -0.3924435855697349 P0CS90 0.036895252764225006 0.002898724749684334 -0.11698000133037567 1.8655600547790527 61.43263532535161 60.0 0.0 no 6486 chrX_520481 20007 essential YJR045C 1102 - TTCGACAACCTTAGGCATTC E|374|Q E|374|K V|373|L V|373|I SSC1 Stress-Seventy subfamily C 654.0 0 1 0 0 0.3498101150578995 P0CS90 0.9168499112129213 0.5840549468994141 0.017147427424788475 0.048154298216104514 47.55130780839761 45.0 0.0 no 6487 chrX_520516r 20009 essential YJR045C 1064 + AGACATATCTGAAGTCTTAT D|356|E silent|GAC>GAT|D|356 SSC1 Stress-Seventy subfamily C 654.0 0 0 0 0 -0.029684208169561577 P0CS90 0.625787615776062 39.01194496752697 30.0 0.0 no 6488 chrX_520582 20010 essential YJR045C 1001 - CGACAGTTCTCTTAACTAGT V|340|L V|340|I SSC1 Stress-Seventy subfamily C 654.0 0 1 0 0 0.5609127661542049 P0CS90 1.0 0.7239322662353516 44.35258485301893 40.0 0.0 no 6489 chrX_520581 20011 essential YJR045C 1002 - TCGACAGTTCTCTTAACTAG D|341|H D|341|N V|340|L V|340|I SSC1 Stress-Seventy subfamily C 654.0 0 1 0 0 0.9237715382056501 P0CS90 0.06323867291212082 0.2577444314956665 1.0 0.7239322662353516 42.76487252768851 40.0 0.0 no 6490 chrX_520567r 20012 essential YJR045C 1013 + AACTGTCGACCCAGTCAAGA T|339|S T|339|I silent|GTC>GTG|V|340 silent|GTC>GTT|V|340 SSC1 Stress-Seventy subfamily C 654.0 0 1 0 0 -1.9909871400773047 P0CS90 0.1714305877685547 0.033945366740226746 49.76186809486131 50.0 0.0 no 6491 chrX_520583 20013 essential YJR045C 1000 - GACAGTTCTCTTAACTAGTG V|340|L V|340|I SSC1 Stress-Seventy subfamily C 654.0 0 1 0 0 0.4888775203402271 P0CS90 1.0 0.7239322662353516 43.00610958196136 40.0 0.0 no 6492 chrX_520635 20014 essential YJR045C 948 - AACTTCATGTTGATATGCTT K|322|N silent|AAG>AAA|K|322 M|321|I M|321|I SSC1 Stress-Seventy subfamily C 654.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.1599682313587851 P0CS90 0.1775592416524887 0.21984602510929108 0.21984602510929108 41.61363688351696 30.0 0.0 no 6493 chrX_520851r 20017 essential YJR045C 729 + ACTAACGGTGACACTCATTT T|244|S T|244|I N|245|K silent|AAC>AAT|N|245 SSC1 Stress-Seventy subfamily C 654.0 0 0 0 0 -0.5143973556230063 P0CS90 0.0 0.0 0.09113838523626328 44.07406357349964 40.0 0.0 no 6494 chrX_520975r 20021 essential YJR045C 605 + CGCTGCCTTAGCTTACGGTT A|203|G A|203|V A|204|G A|204|V SSC1 Stress-Seventy subfamily C 654.0 0 0 0 0 0.5060497572371851 P0CS90 0.006557936780154705 0.002828925149515271 0.05609525367617607 0.0020155876409262423 56.68099991857145 55.00000000000001 0.0 no 6495 chrX_521023 20025 essential YJR045C 560 - AAACGTTCAAACCAACAATT V|193|L V|193|I SSC1 Stress-Seventy subfamily C 654.0 0 0 0 0 -0.09791413686619756 P0CS90 0.0037325427401810884 0.0044609764590859404 36.03517561093412 30.0 0.0 no 6496 chrX_521169r 20026 essential YJR045C 411 + TACTCACCAGCCCAAATCGG Y|138|* silent|TAC>TAT|Y|138 S|139|* S|139|L SSC1 Stress-Seventy subfamily C 654.0 0 1 0 0 -1.9476264001648296 P0CS90 0.024905061349272728 52.30055332120821 55.00000000000001 0.0 no 6497 chrX_521158 20029 essential YJR045C 425 - TCAAGACGAACCCACCGATT L|148|F silent|TTG>TTA|L|148 V|147|L V|147|I SSC1 Stress-Seventy subfamily C 654.0 0 0 0 0 -0.6446520478283642 P0CS90 0.0028745101299136877 0.008710008114576341 0.4435355365276337 48.43262959193458 50.0 0.0 no 6498 chrX_521206r 20030 essential YJR045C 374 + CAACGGGGATGCTTGGGTTG N|126|K silent|AAC>AAT|N|126 SSC1 Stress-Seventy subfamily C 654.0 0 1 0 0 -0.1318961315658475 P0CS90 0.5545904636383057 52.039709779686746 60.0 0.0 no 6499 chrX_521207 20031 essential YJR045C 376 - CTCAACCCAAGCATCCCCGT E|132|Q E|132|K V|131|L V|131|I SSC1 Stress-Seventy subfamily C 654.0 0 0 0 0 -0.9775780068588688 P0CS90 0.5512084364891052 0.8882189393043518 0.041012167930603034 0.3447907865047455 59.246090568513644 60.0 0.0 no 6500 chrX_521314 20035 essential YJR045C 269 - TAGCAAATAGGGTGTTTTCT A|96|P A|96|T SSC1 Stress-Seventy subfamily C 654.0 0 1 0 0 -1.5172598163970648 P0CS90 0.06522384285926819 0.08290612697601317 43.54092097989388 35.0 0.0 no 6501 chrX_521336 20036 essential YJR045C 247 - GTTCACTACGGCTTGACGCT silent|GTG>GTC|V|88 silent|GTG>GTA|V|88 V|88|L V|88|M SSC1 Stress-Seventy subfamily C 654.0 0 0 0 1 0.3629084046961589 P0CS90 0.4704210758209229 0.37880006432533264 54.00397288086282 55.00000000000001 0.0 no 6502 chrX_521399 20039 essential YJR045C 184 - TACTACAGAAGGAGTAGTTC V|68|L V|68|I V|67|L V|67|I SSC1 Stress-Seventy subfamily C 654.0 0 1 0 0 -0.24882501792300066 P0CS90 0.004930636379867792 0.09230045974254608 0.236250713467598 0.7108283638954163 41.16907478845263 40.0 0.0 no 6503 chrX_521521r 20042 essential YJR045C 59 + CACACGTTTGCAGTCAACCA T|21|R T|21|I R|22|G R|22|C SSC1 Stress-Seventy subfamily C 654.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.3250800848514145 P0CS90 0.6874764561653137 0.40800899267196655 0.33753809332847595 0.04767725244164467 50.71077408551229 50.0 0.0 no 6504 chrX_522093r 20046 essential YJR046W 48 - ACTCTATTCAAATCTATCAC R|22|T R|22|K V|23|L V|23|I TAH11 Topo-A Hypersensitive 604.0 0 0 0 0 0.17682295877942966 P47112 0.932735025882721 0.955805003643036 0.9539830088615416 0.9574310183525084 0.5804514288902283 0.9667997360229492 0.08002249151468277 1.0 38.10536331482285 30.0 1.0 no 6505 chrX_522138r 20049 essential YJR046W 93 - AGCAAAATTGCCCTCACCAC L|37|F silent|TTG>TTA|L|37 TAH11 Topo-A Hypersensitive 604.0 0 0 0 0 -0.9689075276158916 P47112 0.9587849974632264 0.0 50.846568090959245 50.0 1.0 no 6506 chrX_522204 20050 essential YJR046W 156 + GTTCTAGATGCACTACTAGC L|54|V silent|CTA>TTA|L|54 TAH11 Topo-A Hypersensitive 604.0 0 0 0 0 -1.379548024278832 P47112 0.9512209892272948 0.2364659160375595 47.90055007698436 45.0 1.0 no 6507 chrX_522246r 20053 essential YJR046W 201 - TCAAAACCTTGACTCGTGTC D|74|H D|74|N G|72|A G|72|D TAH11 Topo-A Hypersensitive 604.0 0 0 0 0 0.7767448287022314 P47112 0.9486550092697144 0.956179976463318 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 45.02043832962033 45.0 1.0 no 6508 chrX_522376 20055 essential YJR046W 328 + CACTGTGCTCCATATATAGT L|111|V silent|CTG>TTG|L|111 TAH11 Topo-A Hypersensitive 604.0 0 0 0 0 -0.21759763530401272 P47112 0.9512209892272948 0.0574452206492424 47.98930843796354 40.0 1.0 no 6509 chrX_522424r 20056 essential YJR046W 379 - CACACTTTTCACACACAGTT V|133|L V|133|M S|132|T S|132|N TAH11 Topo-A Hypersensitive 604.0 0 0 0 0 0.30227651708630043 P47112 0.9539830088615416 0.9587630033493042 0.9512869715690612 0.9536849856376648 0.6298630833625793 0.3853434920310974 0.1858455091714859 0.05763889476656914 45.79861217651205 40.0 1.0 no 6510 chrX_522425r 20058 essential YJR046W 380 - CCACACTTTTCACACACAGT V|133|L V|133|M silent|GTG>GTC|V|133 silent|GTG>GTA|V|133 TAH11 Topo-A Hypersensitive 604.0 0 0 0 0 -0.4067744761081773 P47112 0.9539830088615416 0.9587630033493042 0.6298630833625793 0.3853434920310974 49.37666984721835 45.0 1.0 no 6511 chrX_522531 20061 essential YJR046W 483 + ACACACGATGGTGCAGATGC H|163|D H|163|Y T|162|R T|162|I TAH11 Topo-A Hypersensitive 604.0 0 0 0 0 0.4088060174508303 P47112 0.9473130106925964 0.9489949941635132 0.9476869702339172 0.9472420215606691 50.29722881583029 55.00000000000001 1.0 no 6512 chrX_522590r 20066 essential YJR046W 545 - TAACATAGTCCCTTTCAAAC V|188|L V|188|I TAH11 Topo-A Hypersensitive 604.0 0 0 0 0 0.6980612358532856 P47112 0.9539830088615416 0.9574310183525084 0.31032902002334595 0.19452182948589325 41.773728649645186 35.0 1.0 no 6513 chrX_522672r 20069 essential YJR046W 627 - TCCGTCGTCGCCATAGTCGA silent|ACG>ACC|T|215 silent|ACG>ACA|T|215 D|216|H D|216|N TAH11 Topo-A Hypersensitive 604.0 0 0 0 0 0.5424240337977478 P47112 0.9486550092697144 0.956179976463318 0.15913067758083346 0.2908767759799957 58.20259365267135 60.0 1.0 no 6514 chrX_522804r 20076 essential YJR046W 759 - AACGAAACAATGTTCGCACG silent|TCG>TCC|S|259 silent|TCG>TCA|S|259 TAH11 Topo-A Hypersensitive 604.0 0 0 0 0 1.0320316029378795 P47112 40.253388531136004 45.0 1.0 no 6515 chrX_521172r 20077 essential YJR045C 408 + ACTTACTCACCAGCCCAAAT T|137|S T|137|I Y|138|* silent|TAC>TAT|Y|138 SSC1 Stress-Seventy subfamily C 654.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.3453159089363681 P0CS90 0.713523268699646 0.18081055581569672 50.59219360663496 45.0 0.0 no 6516 chrX_522840r 20078 essential YJR046W 795 - CTCGAGATTGGCGTAGTAAG silent|TCG>TCC|S|271 silent|TCG>TCA|S|271 TAH11 Topo-A Hypersensitive 604.0 0 0 0 0 -0.32689548354573617 P47112 45.794284226332756 50.0 1.0 no 6517 chrX_522846 20079 essential YJR046W 798 + ACTACGCCAATCTCGAGTAA T|267|S T|267|I T|268|R T|268|M TAH11 Topo-A Hypersensitive 604.0 0 0 0 0 0.29024142251790624 P47112 0.9491789937019348 0.9472420215606691 0.9476869702339172 0.9502379894256592 0.8866704106330872 0.17832918465137482 0.3376638889312744 0.2173549234867096 46.48948232134563 45.0 1.0 no 6518 chrX_522926 20084 essential YJR046W 878 + CGCTCAGCAATACTACCCAC A|294|G A|294|V Q|295|E Q|295|* TAH11 Topo-A Hypersensitive 604.0 0 0 0 0 -0.5809589340305997 P47112 0.9484469890594482 0.9504740238189696 0.9590039849281312 0.2733296155929565 0.05190148577094078 1.0 52.261568103931104 55.00000000000001 1.0 no 6519 chrX_522971 20085 essential YJR046W 923 + AGACGCAATGAAGTTTGTTA D|309|E silent|GAC>GAT|D|309 A|310|G A|310|V TAH11 Topo-A Hypersensitive 604.0 0 0 0 0 1.0150132311006144 P47112 0.9532920122146606 0.9484469890594482 0.9504740238189696 1.0 0.20922258496284485 0.16423726081848145 40.733961885099795 35.0 1.0 no 6520 chrX_523028 20087 essential YJR046W 980 + AAACGCTCTTTCCAGATCCA N|328|K silent|AAC>AAT|N|328 A|329|G A|329|V TAH11 Topo-A Hypersensitive 604.0 0 0 0 0 0.09355368522628968 P47112 0.9439849853515624 0.9484469890594482 0.9504740238189696 0.3540942072868347 0.4103146493434906 0.55954909324646 49.895525132854736 45.0 1.0 no 6521 chrX_523029 20088 essential YJR046W 981 + AACGCTCTTTCCAGATCCAC N|328|K silent|AAC>AAT|N|328 A|329|G A|329|V TAH11 Topo-A Hypersensitive 604.0 0 0 0 0 -0.7062172492968277 P47112 0.9439849853515624 0.9484469890594482 0.9504740238189696 0.3540942072868347 0.4103146493434906 0.55954909324646 51.961779203721456 50.0 1.0 no 6522 chrX_523056r 20091 essential YJR046W 1011 - AACAAAACGTGCAGCTCTGG L|343|F silent|TTG>TTA|L|343 TAH11 Topo-A Hypersensitive 604.0 0 0 0 0 1.1243695047388236 P47112 0.9587849974632264 0.031102042645215988 44.767445936387844 50.0 1.0 no 6523 chrX_523080r 20092 essential YJR046W 1035 - TTCATCATGCTGGATATCTG M|351|I M|351|I M|350|I M|350|I TAH11 Topo-A Hypersensitive 604.0 0 0 0 0 -1.012172523267446 P47112 0.9553959965705872 0.9553959965705872 0.9553959965705872 0.9553959965705872 0.18543536961078644 0.18543536961078644 0.04760763049125672 0.04760763049125672 45.41105322682597 40.0 1.0 no 6524 chrX_523081r 20093 essential YJR046W 1036 - TTTCATCATGCTGGATATCT M|351|I M|351|I M|350|I M|350|I TAH11 Topo-A Hypersensitive 604.0 0 0 0 0 0.1891482570511362 P47112 0.9553959965705872 0.9553959965705872 0.9553959965705872 0.9553959965705872 0.18543536961078644 0.18543536961078644 0.04760763049125672 0.04760763049125672 45.69649723994428 35.0 1.0 no 6525 chrX_523141r 20094 essential YJR046W 1096 - TACGTATGCATCAGACCAAA V|372|L V|372|I TAH11 Topo-A Hypersensitive 604.0 0 0 0 0 0.048041923665404135 P47112 0.9539830088615416 0.9574310183525084 0.3438468873500824 0.22490915656089785 43.4834962393827 40.0 1.0 no 6526 chrX_523192r 20095 essential YJR046W 1147 - GTCTCTTTTGGGTAGATTCA D|389|H D|389|N R|388|T R|388|K TAH11 Topo-A Hypersensitive 604.0 0 0 0 0 1.0146714543449495 P47112 0.9486550092697144 0.956179976463318 0.932735025882721 0.955805003643036 0.14017042517662048 1.0 0.6181086301803589 0.9823516607284546 49.24861630899404 40.0 1.0 no 6527 chrX_523222 20096 essential YJR046W 1174 + CAACGTTGACCAATAAGTCT T|393|R T|393|M TAH11 Topo-A Hypersensitive 604.0 0 0 0 0 0.1811176563166597 P47112 0.9476869702339172 0.9502379894256592 0.660034716129303 0.2918922603130341 42.252968432359644 40.0 1.0 no 6528 chrX_523244 20100 essential YJR046W 1196 + GACTTTGGCATTCGTGGAAA T|400|S T|400|I TAH11 Topo-A Hypersensitive 604.0 0 0 0 0 0.2729360978640856 P47112 0.9491789937019348 0.9472420215606691 0.10087858885526656 0.04061591252684593 46.064211180393784 45.0 1.0 no 6529 chrX_523280 20101 essential YJR046W 1232 + CCAACAAGTGATAGCTTCCA Q|412|E Q|412|* Q|413|E Q|413|* TAH11 Topo-A Hypersensitive 604.0 0 0 0 0 0.90956807062962 P47112 0.9590039849281312 0.9590039849281312 1.0 0.9318130016326904 48.12697988322378 45.0 1.0 no 6530 chrX_523280r 20102 essential YJR046W 1235 - CCTTGGAAGCTATCACTTGT K|418|N silent|AAG>AAA|K|418 TAH11 Topo-A Hypersensitive 604.0 0 0 0 0 0.22235410610371525 P47112 0.9355990290641784 0.2313067466020584 49.61414241335046 45.0 1.0 no 6531 chrX_523297r 20103 essential YJR046W 1252 - ATCAGTCATAATCTCATCCT D|424|H D|424|N M|422|I M|422|I TAH11 Topo-A Hypersensitive 604.0 0 0 0 0 -0.15822868346390112 P47112 0.9486550092697144 0.956179976463318 0.9553959965705872 0.9553959965705872 0.018396712839603424 0.3659613430500031 0.5012091398239136 0.5012091398239136 46.14660278379796 35.0 1.0 no 6532 chrX_523324r 20104 essential YJR046W 1279 - TCTTTTATTTATTTTGAAAG R|433|T R|433|K TAH11 Topo-A Hypersensitive 604.0 0 1 0 0 -0.3752614441469291 P47112 0.932735025882721 0.955805003643036 0.013392110355198385 0.21315935254096985 31.229209328086313 15.0 1.0 no 6533 chrX_544074 20107 essential YJR057W 12 + GGCAAATTAATACTGATAGA silent|GGC>GGG|G|5 silent|GGC>GGT|G|5 CDC8 Cell Division Cycle 216.0 0 0 0 0 0.23416913889533525 P00572 35.86736819466864 30.0 1.0 no 6534 chrX_544152r 20108 essential YJR057W 93 - AACTTCAATAGTTTACAGTT K|37|N silent|AAG>AAA|K|37 L|36|F silent|TTG>TTA|L|36 CDC8 Cell Division Cycle 216.0 0 0 0 0 0.018411330215347826 P00572 0.03473731502890587 0.4300230145454407 1.0539920330047607 2.000241994857788 -0.1813800036907196 37.380852284710436 25.0 1.0 no 6535 chrX_544162 20109 essential YJR057W 100 + AACTATTGAAGTTCCCCGAA L|35|V silent|CTA>TTA|L|35 CDC8 Cell Division Cycle 216.0 0 0 0 0 0.0810613215372043 P00572 0.5306103825569153 1.6569559574127195 1.6928000450134275 45.52675301583589 40.0 1.0 no 6536 chrX_544176 20110 essential YJR057W 114 + CCCGAAAGGTCTACCCGAAT silent|CCC>CCG|P|39 silent|CCC>CCT|P|39 P|39|R P|39|L CDC8 Cell Division Cycle 216.0 0 0 0 0 -1.0602663930330862 P00572 0.0 0.0 8.179935455322267 5.069573879241943 51.383966219688254 55.00000000000001 1.0 no 6537 chrX_544250 20112 essential YJR057W 188 + GGCAATTCACCTCTTGTTTT A|64|G A|64|V CDC8 Cell Division Cycle 216.0 0 0 0 0 0.6350522551483384 P00572 0.05009341984987259 0.1984461545944214 1.13224995136261 0.07440199702978134 1.1090999841690063 -0.2272599935531616 1.7141239643096924 0.9352499842643738 50.257231335740926 40.0 1.0 no 6538 chrX_544202 20113 essential YJR057W 140 + ACTCATAAACGAATATTTGA silent|CTC>CTG|L|48 silent|CTC>CTT|L|48 L|48|V L|48|F CDC8 Cell Division Cycle 216.0 0 0 0 0 0.7726464839778046 P00572 0.10035790503025056 0.08607136458158493 0.7502700090408325 0.8103820085525513 0.3591200113296509 0.639739990234375 1.351660966873169 0.3840169906616211 33.79759271361229 25.0 1.0 no 6539 chrX_544479 20118 essential YJR057W 417 + AACGCCGAAAAATCTGGATT N|140|K silent|AAC>AAT|N|140 A|141|G A|141|V CDC8 Cell Division Cycle 216.0 0 0 0 0 -1.0164909390902048 P00572 0.6457933187484741 0.36022090911865234 0.3114529550075531 -0.7484779953956604 0.3686380088329315 1.8176000118255613 0.5608999729156494 0.5865200161933899 40.659933758168286 40.0 1.0 no 6540 chrX_544483r 20119 essential YJR057W 424 - GTCACCAAATCCAGATTTTT D|148|H D|148|N G|147|A G|147|D CDC8 Cell Division Cycle 216.0 0 0 0 0 -0.5428310793775111 P00572 0.013603271916508676 0.024938451126217842 0.0 0.0 -0.5784819722175598 -0.5258219838142395 2.47802996635437 3.088468074798584 45.03768485793705 35.0 1.0 no 6541 chrX_555931 20122 essential YJR064W 17 + ACAACCTCCTATGGAAATGC Q|7|E Q|7|* P|8|A P|8|S CCT5 Chaperonin Containing TCP-1 562.0 0 0 0 0 0.6882119431723411 P40413 0.9590039849281312 0.9562489986419678 0.9498909711837769 45.76133359911114 45.0 1.0 no 6542 chrX_555938r 20123 essential YJR064W 27 - GACAGATCCGGCATTTCCAT silent|CTG>CTC|L|15 silent|CTG>CTA|L|15 CCT5 Chaperonin Containing TCP-1 562.0 0 0 0 0 -1.8125371896490032 P40413 53.222821621982916 50.0 1.0 no 6543 chrX_555966r 20125 essential YJR064W 55 - CATCTCGTCTTGTGCCACAA E|24|D silent|GAG>GAA|E|24 E|24|Q E|24|K CCT5 Chaperonin Containing TCP-1 562.0 0 0 0 0 0.6532722242316965 P40413 0.94931298494339 0.956179976463318 0.9475290179252625 0.024183616042137143 0.012639591470360756 0.06243781000375748 52.66990512332842 50.0 1.0 no 6544 chrX_556088 20127 essential YJR064W 174 + TCTATTATCAAAACTTCGTT S|59|C S|59|F CCT5 Chaperonin Containing TCP-1 562.0 0 0 0 0 -0.09222955572629424 P40413 0.945252001285553 0.9294660091400146 0.04383717849850655 0.04098755493760109 0.33480000495910645 0.4745999872684479 36.71442890040584 25.0 1.0 no 6545 chrX_556188r 20129 essential YJR064W 277 - CTCATTATCTAGCTCCATTT E|99|Q E|99|K CCT5 Chaperonin Containing TCP-1 562.0 0 0 0 0 -2.877313125179053 P40413 0.956179976463318 0.9475290179252625 0.6429631114006042 0.3679729998111725 0.2125999927520752 -0.10499999672174454 0.8046000003814697 0.5727999806404114 47.644728910706256 35.0 1.0 yes 6546 chrX_556189r 20130 essential YJR064W 278 - TCTCATTATCTAGCTCCATT E|99|Q E|99|K E|99|D silent|GAG>GAA|E|99 CCT5 Chaperonin Containing TCP-1 562.0 0 0 0 0 0.33010064101503817 P40413 0.956179976463318 0.9475290179252625 0.94931298494339 0.6429631114006042 0.3679729998111725 0.5604366660118103 0.2125999927520752 -0.10499999672174454 0.2554000020027161 0.8046000003814697 0.5727999806404114 0.5835999846458435 48.47930668259761 35.0 1.0 no 6547 chrX_556267 20131 essential YJR064W 353 + TACTACTGGTGTTGTTGTTC T|119|S T|119|I T|120|S T|120|I CCT5 Chaperonin Containing TCP-1 562.0 0 0 0 0 0.3732950910617302 P40413 0.9491789937019348 0.9472420215606691 0.9491789937019348 0.9472420215606691 0.0 0.0 0.0 0.0 -0.3759999871253967 5.9079999923706055 0.725600004196167 -0.6481999754905701 47.172983302698746 40.0 1.0 no 6548 chrX_556294 20132 essential YJR064W 380 + TGCGCTACTTGACCAAGCAT A|128|G A|128|V L|129|V silent|CTA>TTA|L|129 CCT5 Chaperonin Containing TCP-1 562.0 0 0 0 0 -0.0942601096741679 P40413 0.9484469890594482 0.9504740238189696 0.9512209892272948 0.2747231721878052 0.10056472569704056 0.009464084170758724 1.8176000118255613 1.4021999835968018 2.315000057220459 51.45257243375903 50.0 1.0 no 6549 chrX_556374r 20134 essential YJR064W 463 - TAACTTGGAAATGGCTAATT K|160|N silent|AAG>AAA|K|160 CCT5 Chaperonin Containing TCP-1 562.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.2305853564621207 P40413 0.9355990290641784 0.3539859354496002 1.274399995803833 36.92349230686517 30.0 1.0 no 6550 chrX_556494r 20138 essential YJR064W 583 - AGCAAATCTATCATGATCCT A|201|P A|201|T CCT5 Chaperonin Containing TCP-1 562.0 0 0 0 0 -6.433488575930637 P40413 0.9573720097541808 0.9523990154266356 0.02666500955820084 0.021203106269240383 7.241799831390381 3.204400062561035 43.598002154304716 35.0 1.0 yes 6551 chrX_556574 20140 essential YJR064W 660 + TTCGATTTAATCAAAATGCA F|221|L silent|TTC>TTT|F|221 CCT5 Chaperonin Containing TCP-1 562.0 0 1 0 0 -0.18762323259795627 P40413 0.9387490153312684 0.7797722220420837 1.846199989318848 0.902999997138977 35.07148475229445 25.0 1.0 no 6552 chrX_556676r 20142 essential YJR064W 765 - TCTTTTGGTAAAACACATTT E|262|Q E|262|K CCT5 Chaperonin Containing TCP-1 562.0 0 0 0 0 -1.2144609711815493 P40413 0.956179976463318 0.9475290179252625 0.058200001716613776 0.14900000393390656 -0.2125999927520752 -0.3463999927043915 36.896732355923916 25.0 1.0 no 6553 chrX_556882r 20146 essential YJR064W 971 - CCTCATCGTCAAACCCCCAT E|330|Q E|330|K E|330|D silent|GAG>GAA|E|330 CCT5 Chaperonin Containing TCP-1 562.0 0 0 0 0 -1.6563179702946698 P40413 0.956179976463318 0.9475290179252625 0.94931298494339 0.09051907062530518 0.08547478169202805 0.12061654031276706 -0.1746000051498413 0.019600000232458115 0.2863999903202057 56.796543529074434 55.00000000000001 1.0 no 6554 chrX_556934r 20148 essential YJR064W 1023 - CCACCTACCCATCTTACGGC G|347|A G|347|D G|348|R G|348|S CCT5 Chaperonin Containing TCP-1 562.0 0 0 0 0 -1.5889355700708618 P40413 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.06383635103702545 0.03168168291449547 0.03115464001893997 0.05155453458428383 1.406999945640564 0.053599998354911804 -0.2152000069618225 -0.2870000004768372 -0.1687999963760376 0.748199999332428 58.48447654277828 60.0 1.0 no 6555 chrX_556957r 20149 essential YJR064W 1046 - TGGCAATGTGTTCTAGTTCT A|355|P A|355|T CCT5 Chaperonin Containing TCP-1 562.0 0 0 0 0 1.0740077343241154 P40413 0.9573720097541808 0.9523990154266356 0.007811644580215216 0.007523698732256889 2.5271999835968018 0.4023999869823456 1.5157999992370603 0.7928000092506409 48.5896407283347 40.0 1.0 no 6556 chrX_556970 20150 essential YJR064W 1056 + CACATTGCCATTTCCACAAA H|353|Q silent|CAC>CAT|H|353 CCT5 Chaperonin Containing TCP-1 562.0 0 0 0 0 -0.03347674519445512 P40413 0.9588389992713928 0.32516810297966003 1.410599946975708 0.3778000175952912 46.557971240565045 40.0 1.0 no 6557 chrX_557046r 20151 essential YJR064W 1135 - AAACTCCTGCTCGTAAATTC E|384|D silent|GAG>GAA|E|384 E|384|Q E|384|K CCT5 Chaperonin Containing TCP-1 562.0 0 0 0 0 0.8197248101071299 P40413 0.94931298494339 0.956179976463318 0.9475290179252625 0.565900444984436 0.4854556024074554 1.0 -0.1987999975681305 0.1404000073671341 -0.07559999823570251 43.0440749833856 40.0 1.0 no 6558 chrX_557120 20153 essential YJR064W 1206 + ACTGTAACATGTTTTGTTCG T|403|S T|403|I CCT5 Chaperonin Containing TCP-1 562.0 0 0 0 0 1.3445549586652623 P40413 0.9491789937019348 0.9472420215606691 0.16665449738502502 0.19336548447608948 0.4767999947071075 -2.0706000328063965 41.956420614268886 35.0 1.0 no 6559 chrX_558156r 20154 essential YJR065C 980 + GACTCCTTTACCCACGGTAG T|328|S T|328|I P|329|A P|329|S ARP3 Actin-Related Protein 449.0 0 0 0 0 -0.20212574212846213 P47117 0.429602712392807 0.09638982266187668 0.03589751198887825 0.527502179145813 1.8028000593185425 2.3015999794006348 54.53822909184226 55.00000000000001 0.0 no 6560 chrX_558162r 20155 essential YJR065C 974 + CTTCTTGACTCCTTTACCCA F|326|L silent|TTC>TTT|F|326 ARP3 Actin-Related Protein 449.0 0 0 0 0 0.23441286071675266 P47117 0.16976696252822876 0.9121999740600586 53.89473356773874 45.0 0.0 no 6561 chrX_558333r 20156 essential YJR065C 803 + CGTCTGTCCAGATATTGTAA silent|GTC>GTG|V|269 silent|GTC>GTT|V|269 ARP3 Actin-Related Protein 449.0 0 0 0 0 0.0032893057290055983 P47117 45.86910417531697 40.0 0.0 no 6562 chrX_558489 20159 essential YJR065C 650 - TGACGTAACCTTCCGCCACT V|223|L V|223|I ARP3 Actin-Related Protein 449.0 0 0 0 0 0.4797097697040254 P47117 0.09202969819307327 0.02846923470497132 54.92523303906614 55.00000000000001 0.0 no 6563 chrX_558504r 20162 essential YJR065C 632 + TGTCACCCACGTCATCCCAG silent|GTC>GTG|V|212 silent|GTC>GTT|V|212 T|213|S T|213|I ARP3 Actin-Related Protein 449.0 0 0 0 0 -0.5116886781350817 P47117 0.02352144755423069 0.0027838870882987976 59.485023274191406 60.0 0.0 no 6564 chrX_558668 20166 essential YJR065C 471 - ACTTGCTCTCTGTTTTCTGG V|164|L V|164|M E|162|D silent|GAG>GAA|E|162 ARP3 Actin-Related Protein 449.0 0 0 0 0 0.2475423607739004 P47117 0.419698178768158 0.18559305369853973 0.0 52.048175726903146 45.0 0.0 no 6565 chrX_558666r 20167 essential YJR065C 470 + TCCAGAAAACAGAGAGCAAG P|158|R P|158|L P|158|A P|158|S ARP3 Actin-Related Protein 449.0 0 0 0 0 1.0393116880109476 P47117 0.001986338058486581 0.0026995367370545864 0.08009947091341019 0.012041096575558186 40.23342406420392 45.0 0.0 no 6566 chrX_558665 20168 essential YJR065C 474 - GCCACTTGCTCTCTGTTTTC silent|GTG>GTC|V|164 silent|GTG>GTA|V|164 A|165|P A|165|T ARP3 Actin-Related Protein 449.0 0 0 0 0 0.19442681573358275 P47117 0.008866354823112488 0.0060872966423630714 57.017046127224376 50.0 0.0 no 6567 chrX_558794 20170 essential YJR065C 345 - TCCACTTGACCGTGTCTGAT silent|GTG>GTC|V|121 silent|GTG>GTA|V|121 E|122|Q E|122|K ARP3 Actin-Related Protein 449.0 0 0 0 1 0.8155545291015276 P47117 0.2888464033603668 0.08924750983715057 53.604834398707396 50.0 0.0 no 6568 chrX_558979 20175 essential YJR065C 160 - TGCTTCATTACTAACTGCTG A|60|P A|60|T E|59|Q E|59|K ARP3 Actin-Related Protein 449.0 0 0 0 0 -0.07498553029655522 P47117 1.8523999452590945 -0.3066000044345856 1.997599959373474 0.8669999837875366 44.875275190347004 40.0 0.0 no 6569 chrX_558980 20176 essential YJR065C 159 - GCTTCATTACTAACTGCTGA A|60|P A|60|T E|59|Q E|59|K ARP3 Actin-Related Protein 449.0 0 0 0 0 0.8693070331643459 P47117 1.8523999452590945 -0.3066000044345856 1.997599959373474 0.8669999837875366 46.11087253930759 40.0 0.0 no 6570 chrX_559013r 20178 essential YJR065C 123 + TCAAATACAAAGAAGTCCTC S|42|* S|42|L ARP3 Actin-Related Protein 449.0 0 0 0 0 -2.312076069089992 P47117 0.4571326673030853 37.05139602610535 35.0 0.0 yes 6571 chrX_559118 20185 essential YJR065C 21 - CCATTGTCCATGACAACAGC G|14|R G|14|S ARP3 Actin-Related Protein 449.0 0 0 0 0 -1.2091188669289283 P47117 0.0 0.0 50.02946687560376 50.0 0.0 no 6572 chrX_567168 20188 essential YJR067C 257 - CATCAATATATGCCTTACTG D|92|H D|92|N YAE1 141.0 0 0 0 0 0.5294461036899712 P47118 0.9486550092697144 0.956179976463318 0.06487033516168594 0.2548050880432129 41.56317461693357 35.0 0.0 no 6573 chrX_567201 20189 essential YJR067C 224 - CATCACCAAAACGTGTTCGT D|81|H D|81|N G|80|A G|80|D YAE1 141.0 0 0 0 0 -0.2232929662996826 P47118 0.9486550092697144 0.956179976463318 0.9499930143356324 0.9446240067481996 0.12624555826187134 0.5027696490287781 0.18482135236263275 0.04395027086138725 45.49141493857826 45.0 0.0 no 6574 chrX_567235r 20190 essential YJR067C 187 + AACAAGTTGGCATAATTATG Q|64|E Q|64|* YAE1 141.0 0 0 0 0 -0.5353498487349899 P47118 0.9590039849281312 0.4377417266368866 36.1930961930679 30.0 0.0 no 6575 chrX_567236r 20192 essential YJR067C 186 + AAACAAGTTGGCATAATTAT Q|64|E Q|64|* YAE1 141.0 0 0 0 0 -0.11624080311091232 P47118 0.9590039849281312 0.4377417266368866 34.93465493444933 25.0 0.0 no 6576 chrX_567272r 20193 essential YJR067C 150 + TTCAATGATGGTTTCCCAAC F|51|L silent|TTC>TTT|F|51 YAE1 141.0 0 0 0 0 0.3970444595338051 P47118 0.9387490153312684 0.0 45.76199356939708 40.0 0.0 no 6577 chrX_567273r 20194 essential YJR067C 149 + TTTCAATGATGGTTTCCCAA F|51|L silent|TTC>TTT|F|51 YAE1 141.0 0 0 0 0 -0.09651556799252148 P47118 0.9387490153312684 0.0 45.580589034785596 35.0 0.0 no 6578 chrX_567701 20198 essential YJR068W 58 + AATCATTGGCACAACAACCC S|21|* S|21|L RFC2 Replication Factor C 353.0 0 0 0 0 -0.906591609620094 P40348 0.9298099875450134 0.347007691860199 46.064431315153065 45.0 1.0 no 6579 chrX_567702 20199 essential YJR068W 59 + ATCATTGGCACAACAACCCT S|21|* S|21|L RFC2 Replication Factor C 353.0 0 0 0 0 -1.4637011118624832 P40348 0.9298099875450134 0.347007691860199 49.192917137437455 45.0 1.0 no 6580 chrX_567739r 20201 essential YJR068W 99 - GTCACTTCATCTAGGTTTTT silent|GTG>GTC|V|39 silent|GTG>GTA|V|39 V|39|L V|39|M RFC2 Replication Factor C 353.0 0 0 0 0 0.25077645277437965 P40348 0.9539830088615416 0.9587630033493042 0.013710474595427513 0.0028750000055879354 -1.1823999881744385 -0.4767999947071075 -1.649399995803833 -0.6650000214576721 47.46752516992643 35.0 1.0 no 6581 chrX_567863r 20204 essential YJR068W 223 - TTCTTTTGTTAGCGCTAAAA E|81|Q E|81|K RFC2 Replication Factor C 353.0 0 0 0 0 0.21480807327729048 P40348 0.956179976463318 0.9475290179252625 0.7670866250991821 0.041328810155391686 0.7167999744415283 0.13619999587535858 40.725542419808455 30.0 1.0 no 6582 chrX_568003r 20206 essential YJR068W 363 - TTCTCCAAGTCATGTTTGCT E|127|D silent|GAG>GAA|E|127 E|127|Q E|127|K RFC2 Replication Factor C 353.0 0 0 0 0 0.17026521896100458 P40348 0.94931298494339 0.956179976463318 0.9475290179252625 0.9216934442520142 0.2758915722370148 0.4963918924331665 0.3441999852657318 -0.15559999644756314 -0.4187999963760376 50.67233409506928 40.0 1.0 no 6583 chrX_568039r 20207 essential YJR068W 399 - TCGAGAATAATGATCTTATA D|140|H D|140|N RFC2 Replication Factor C 353.0 0 0 0 0 -1.3026512871904354 P40348 0.9486550092697144 0.956179976463318 0.0 0.0 5.642199993133545 1.791800022125244 33.97676699005541 25.0 1.0 no 6584 chrX_568082r 20209 essential YJR068W 442 - ACGTAATGCACTCTGTGCAT R|154|P R|154|H RFC2 Replication Factor C 353.0 0 0 0 0 -0.813720814603532 P40348 0.9099509716033936 0.9570810198783876 0.0 0.0 6.75059986114502 1.5836000442504885 48.8116012074874 45.0 1.0 no 6585 chrX_567839r 20210 essential YJR068W 199 - AGACGTTTTACCAGTTCCTG silent|ACG>ACC|T|72 silent|ACG>ACA|T|72 RFC2 Replication Factor C 353.0 0 0 0 0 0.4589773357041497 P40348 50.067314534657385 45.0 1.0 no 6586 chrX_568239r 20211 essential YJR068W 599 - GTTCGCTGATAAACCTCAAA E|206|Q E|206|K S|205|T S|205|N RFC2 Replication Factor C 353.0 0 0 0 0 -0.5988076629149672 P40348 0.956179976463318 0.9475290179252625 0.9512869715690612 0.9536849856376648 0.5042689442634583 0.955422341823578 0.08786439895629883 0.02659996971487999 -0.5350000262260437 -0.2867999970912933 -1.3586000204086304 0.335999995470047 42.82580881869546 40.0 1.0 no 6587 chrX_568389 20213 essential YJR068W 746 + AAACATAACTTCTACCCAAG N|250|K silent|AAC>AAT|N|250 RFC2 Replication Factor C 353.0 0 0 0 0 -0.2410244362970892 P40348 0.9439849853515624 0.8743523955345154 -0.4586000144481659 39.21453289135803 35.0 1.0 no 6588 chrX_568403r 20214 essential YJR068W 763 - ACCAGCTAATTCTTCCACTT G|261|R G|261|S G|261|A G|261|D RFC2 Replication Factor C 353.0 0 0 0 0 0.6660100815882852 P40348 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 3.271199941635132 3.661200046539306 3.51200008392334 3.511199951171875 50.27807542065864 40.0 1.0 no 6589 chrX_571323 20215 essential YJR072C 782 - CACGTTCTTGCTTATAGTAT R|267|P R|267|H E|266|Q E|266|K NPA3 Nucleolar Preribosomal Associated 385.0 0 1 0 0 0.9453237056708406 P47122 0.9099509716033936 0.9570810198783876 0.956179976463318 0.9475290179252625 0.008477671071887016 0.013801981694996357 0.09100192040205002 0.04267222061753273 44.71287143522909 35.0 0.0 no 6590 chrX_571251r 20216 essential YJR072C 851 + ATCATTGAATGGCCTGATGA S|285|* S|285|L NPA3 Nucleolar Preribosomal Associated 385.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.8547254088067677 P47122 0.9298099875450134 0.17188559472560885 45.53058008049953 40.0 0.0 no 6591 chrX_571413 20218 essential YJR072C 692 - AAACGCCCACGACGTCTAGC V|237|L V|237|I G|236|A G|236|D NPA3 Nucleolar Preribosomal Associated 385.0 0 0 0 0 -1.0981944718225856 P47122 0.9539830088615416 0.9574310183525084 0.9499930143356324 0.9446240067481996 0.01306380145251751 0.09210301190614699 0.07979901134967804 0.003688317025080323 1.8212820291519165 2.1949999332427983 -0.22629599273204806 0.059962000697851174 52.44078198166568 60.0 0.0 no 6592 chrX_571776 20227 essential YJR072C 329 - TCCACACAAAACATTCGATT W|116|S W|116|* W|116|C W|116|* NPA3 Nucleolar Preribosomal Associated 385.0 0 0 0 0 -0.596764047106945 P47122 0.8858469724655151 0.8858469724655151 0.0 0.0 1.8988480567932131 1.8969680070877075 1.1389000415802002 0.7168999314308167 40.50056468576446 35.0 0.0 no 6593 chrX_571781 20228 essential YJR072C 324 - ACAAAACATTCGATTTGGCC V|115|L V|115|M C|113|S C|113|Y NPA3 Nucleolar Preribosomal Associated 385.0 0 0 0 0 0.3247507373578311 P47122 0.9539830088615416 0.9587630033493042 0.9421560168266296 0.9290120005607604 0.022878313437104225 0.0073735248297452935 0.009413596242666245 0.0032952420879155397 1.2458839416503906 1.5699540376663208 0.2617439925670624 5.354147911071777 -2.6735999584198 -3.499000072479248 2.094000101089477 10.30820083618164 42.49726267932851 40.0 0.0 no 6594 chrX_571965 20231 essential YJR072C 140 - TATCGATGTTTGCACCATAG D|53|H D|53|N NPA3 Nucleolar Preribosomal Associated 385.0 0 0 0 0 -0.4744624876600818 P47122 0.9486550092697144 0.956179976463318 0.0 0.0 0.9057679772377014 -0.3266020119190216 45.18690056771578 40.0 0.0 no 6595 chrX_572006 20233 essential YJR072C 99 - TCAAGATTGATTACGTATGG D|40|H D|40|N NPA3 Nucleolar Preribosomal Associated 385.0 0 0 0 0 -4.3321986793462575 P47122 0.9486550092697144 0.956179976463318 0.0 0.0 0.3555020093917847 0.3679833710193634 11.022000312805176 2.65339994430542 38.64228643518783 35.0 0.0 yes 6596 chrX_572091r 20235 essential YJR072C 11 + CACAATCATATGTATTGGTA T|5|R T|5|I I|6|M silent|ATC>ATT|I|6 NPA3 Nucleolar Preribosomal Associated 385.0 0 0 0 0 0.30409396856622056 P47122 0.9476869702339172 0.9472420215606691 0.9598389863967896 0.16675294935703278 0.223872110247612 0.05929863080382348 10.606160163879396 -1.4929646253585815 0.045138001441955566 39.049966584437975 30.0 0.0 no 6597 chrX_575658 20237 essential YJR076C 924 - CCATTCAATTTTGTCAGATT G|315|R G|315|S L|313|F silent|TTG>TTA|L|313 CDC11 Cell Division Cycle 415.0 0 1 0 0 -0.15751186534978873 P32458 0.4761994183063507 0.6734930872917175 0.1430855244398117 42.51116136649324 30.0 0.0 no 6598 chrX_575832 20238 essential YJR076C 750 - TCCACGTCCAGTATGCCCCA silent|GTG>GTC|V|256 silent|GTG>GTA|V|256 E|257|Q E|257|K CDC11 Cell Division Cycle 415.0 0 0 0 1 -1.0073929758285585 P32458 0.15913571417331696 0.14792104065418246 63.227668484296096 60.0 0.0 no 6599 chrX_575798r 20239 essential YJR076C 781 + TCTCTGATTTTGTTATCTTA S|262|C S|262|F I|261|M silent|ATC>ATT|I|261 CDC11 Cell Division Cycle 415.0 0 0 0 0 1.6131092449100572 P32458 0.002770586404949427 0.001759291859343648 0.22714853286743164 0.5136200189590454 -0.043299999088048935 -0.10440000146627426 -0.07400000095367433 -0.5802000164985657 18.84499931335449 -1.6134500503540041 41.249768660201475 25.0 0.0 no 6600 chrX_575849r 20243 essential YJR076C 730 + TTCGTGGCAGAAAGTATCCA R|245|G R|245|C CDC11 Cell Division Cycle 415.0 0 0 0 0 0.31481443418121136 P32458 0.015402750112116337 0.002355781616643071 47.910901488995364 45.0 0.0 no 6601 chrX_575913r 20246 essential YJR076C 666 + CTTCTACCTTTTGCTATTAT L|224|V silent|CTA>TTA|L|224 P|225|A P|225|S CDC11 Cell Division Cycle 415.0 0 0 0 0 0.06819359442550169 P32458 0.3033647537231445 0.0 0.0 1.3285200595855713 7.4653000831604 8.441760063171388 1.9026000499725344 45.074984792373705 30.0 0.0 no 6602 chrX_576056 20249 essential YJR076C 526 - TTTCAGTTCATCTCTTGTCA silent|CTG>CTC|L|181 silent|CTG>CTA|L|181 CDC11 Cell Division Cycle 415.0 0 0 0 0 0.1988535231119672 P32458 48.355873714855754 35.0 0.0 no 6603 chrX_576079 20250 essential YJR076C 503 - AATCTGATTTGCTGATCACA D|174|H D|174|N CDC11 Cell Division Cycle 415.0 0 0 0 0 -0.8808421913486206 P32458 0.0 0.0 -0.07485999912023544 0.13184000551700592 1.2838499546051023 0.8837499618530273 42.93790718442443 35.0 0.0 no 6604 chrX_576142 20252 essential YJR076C 440 - CATCAATCTCTTTTAAACCG D|153|H D|153|N CDC11 Cell Division Cycle 415.0 0 0 0 0 0.5917700733039435 P32458 0.0 0.0 5.888319969177246 2.113719940185547 40.004292639545845 35.0 0.0 no 6605 chrX_576244 20254 essential YJR076C 338 - CCAATAAGATTTCATCATAT L|119|F silent|TTG>TTA|L|119 CDC11 Cell Division Cycle 415.0 0 0 0 0 -0.6185305450093734 P32458 0.11669935286045074 0.21104000508785248 0.4672000110149384 36.91894205236093 25.0 0.0 no 6606 chrX_576309 20255 essential YJR076C 273 - TCGAGAGAATCACCGAATCC D|98|H D|98|N CDC11 Cell Division Cycle 415.0 0 0 0 0 -0.09718689922320307 P32458 0.009625596925616264 0.2591860890388489 0.707260012626648 0.6446400284767151 0.1812000274658203 -0.1003333330154419 45.86356502664444 50.0 0.0 no 6607 chrX_576328r 20257 essential YJR076C 251 + ACTTAATATCATCGATACTC L|85|V L|85|F CDC11 Cell Division Cycle 415.0 0 0 0 0 -2.0228132206853724 P32458 0.017220590263605118 0.014008790254592896 1.5859999656677246 1.295300006866455 1.1239999532699585 -0.001000000047497451 37.594840191026385 30.0 0.0 yes 6608 chrX_576198 20258 essential YJR076C 384 - ACTCTGCCGTCCTTAAATCT R|134|T R|134|K V|135|L V|135|I CDC11 Cell Division Cycle 415.0 0 0 0 0 -0.20454404549576144 P32458 0.0 0.0 0.027614237740635872 0.25928425788879395 -1.3345600366592407 -1.1644999980926514 0.3640399873256683 -1.2908799648284912 51.423549192870844 45.0 0.0 no 6609 chrX_587761r 20263 essential YJR089W 46 - CCTTAACCTATTCTCCAGTT R|22|T R|22|K R|20|S silent|AGG>AGA|R|20 0 0 0 0 -0.8933895914115978 P47134 0.932735025882721 0.955805003643036 0.9087679982185364 0.5722506642341614 1.0 0.0 50.67715075511671 40.0 1.0 no 6610 chrX_587998 20265 essential YJR089W 280 + AGACTCTAAGCAATATAATG T|95|S T|95|I L|96|V silent|CTA>TTA|L|96 0 0 0 0 -1.304780777552448 P47134 0.9491789937019348 0.9472420215606691 0.9512209892272948 0.11465766280889512 0.028205035254359245 0.7507507801055908 34.714575095258 30.0 1.0 no 6611 chrX_588089 20267 essential YJR089W 371 + GGACTATAGCTTCCATATGG D|125|E silent|GAC>GAT|D|125 0 0 0 0 0.8194272250250556 P47134 0.9532920122146606 1.0 47.81732602106194 45.0 1.0 no 6612 chrX_588087 20268 essential YJR089W 369 + ACGGACTATAGCTTCCATAT T|124|R T|124|M D|125|E silent|GAC>GAT|D|125 0 0 0 0 0.7265986526245958 P47134 0.9476869702339172 0.9502379894256592 0.9532920122146606 0.5542775988578796 0.05964751169085504 1.0 46.99377858424469 40.0 1.0 no 6613 chrX_588201r 20271 essential YJR089W 486 - TCATTTTGAGAACCACTGTG E|169|Q E|169|K 0 0 0 0 -0.006347702681539183 P47134 0.956179976463318 0.9475290179252625 0.5846938490867615 0.8981341123580933 43.64398768362423 40.0 1.0 no 6614 chrX_588212 20272 essential YJR089W 494 + TTCTCAAAATGAACATCCGC S|166|C S|166|F Q|167|E Q|167|* 0 0 0 0 -0.4122066417586076 P47134 0.945252001285553 0.9294660091400146 0.9590039849281312 0.0442182794213295 0.051156409084796906 0.6632456779479979 41.49798103630104 40.0 1.0 no 6615 chrX_588213 20273 essential YJR089W 495 + TCTCAAAATGAACATCCGCT Q|167|E Q|167|* S|166|C S|166|F 0 0 0 0 -0.07683116252002861 P47134 0.9590039849281312 0.945252001285553 0.9294660091400146 0.6632456779479979 0.0442182794213295 0.051156409084796906 42.906818418792795 40.0 1.0 no 6616 chrX_588228r 20274 essential YJR089W 513 - ACCATCTTTTCTATACCCAG M|177|I M|177|I V|178|L V|178|M 0 0 0 0 0.002681131407119397 P47134 0.9553959965705872 0.9553959965705872 0.9539830088615416 0.9587630033493042 0.4150637686252594 0.4150637686252594 0.2567867636680603 0.08876528590917587 49.598371366121064 40.0 1.0 no 6617 chrX_588277r 20276 essential YJR089W 562 - ATCGCCTAAGCCTTCTATGC D|194|H D|194|N G|193|A G|193|D 0 0 0 0 0.3977647083423705 P47134 0.9486550092697144 0.956179976463318 0.9499930143356324 0.9446240067481996 0.02715545333921909 0.08731319010257721 0.5776366591453552 0.9812032580375672 54.014688438480384 50.0 1.0 no 6618 chrX_588386 20279 essential YJR089W 668 + TCCGATGAGCCGACATTATA P|224|R P|224|L P|224|A P|224|S 0 1 0 0 0.4403463483355203 P47134 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 48.269419075315454 45.0 1.0 no 6619 chrX_588504 20281 essential YJR089W 786 + TCTCCAACTTTAGGCGAAAA P|264|A P|264|S S|263|C S|263|F 0 1 0 0 0.782473731876608 P47134 0.9562489986419678 0.9498909711837769 0.945252001285553 0.9294660091400146 0.8658284544944763 0.7477268576622009 0.08785558491945268 0.2417831569910049 43.02251938171878 40.0 1.0 no 6620 chrX_588544 20282 essential YJR089W 826 + ACACGAAAACCGCTTCTCAA T|277|R T|277|M N|276|K silent|AAC>AAT|N|276 0 0 0 0 0.5096423026373245 P47134 0.9476869702339172 0.9502379894256592 0.9439849853515624 0.5469469428062439 0.1450585275888443 0.17620760202407834 44.19754169921856 45.0 1.0 no 6621 chrX_588606r 20283 essential YJR089W 891 - TCATTATAATCGTCAAGTTG E|304|Q E|304|K 0 0 0 0 -0.019280456759021902 P47134 0.956179976463318 0.9475290179252625 0.2838625311851501 0.3842550218105316 37.52296818315165 30.0 1.0 no 6622 chrX_589009 20287 essential YJR089W 1291 + TCATAAAAAATAGAGATGTA I|431|M silent|ATC>ATT|I|431 0 0 0 0 0.18022589892775467 P47134 0.9598389863967896 0.054201781749725335 28.593528421896394 20.0 1.0 no 6623 chrX_589116 20289 essential YJR089W 1398 + ACCTCATCACATTTGCTCAA silent|ACC>ACG|T|467 silent|ACC>ACT|T|467 T|467|S T|467|I 0 0 0 0 0.2101423244032697 P47134 0.9491789937019348 0.9472420215606691 0.35123175382614136 0.694486141204834 48.444215763081615 40.0 1.0 no 6624 chrX_589182 20290 essential YJR089W 1464 + GGCATAAATACAGACACAAA silent|GGC>GGG|G|489 silent|GGC>GGT|G|489 0 0 0 0 -1.9599389702837853 P47134 36.75669602077238 35.0 1.0 no 6625 chrX_589358r 20294 essential YJR089W 1643 - CTTCTGGGGATCCACCATTG E|554|Q E|554|K 0 1 0 0 -0.3188108385813433 P47134 0.956179976463318 0.9475290179252625 0.2549202442169189 0.3162636756896973 54.40301166013092 55.00000000000001 1.0 no 6626 chrX_589450 20295 essential YJR089W 1732 + ATCAAAAAGATTCAACTGTA Q|579|E Q|579|* 0 1 0 0 0.25143994277299186 P47134 0.9590039849281312 1.0 32.82026786818352 25.0 1.0 no 6627 chrX_589536r 20297 essential YJR089W 1821 - CCTCTCCTTTGTTCCTCTTT R|613|T R|613|K G|614|R G|614|S 0 0 0 0 0.4934916158499521 P47134 0.932735025882721 0.955805003643036 0.941340982913971 0.951104998588562 0.4818689525127411 0.9604851007461548 0.3616385757923126 0.4159331321716309 58.49976343237808 45.0 1.0 no 6628 chrX_589537r 20298 essential YJR089W 1822 - GCCTCTCCTTTGTTCCTCTT G|614|R G|614|S G|614|A G|614|D 0 0 0 0 -0.20210830721269704 P47134 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.3616385757923126 0.4159331321716309 0.5238774418830872 0.21991445124149325 62.30180273307179 50.0 1.0 no 6629 chrX_589623r 20300 essential YJR089W 1908 - CCACTTATTGATAGGCTTCT S|642|T S|642|N G|643|R G|643|R 0 1 0 0 0.31100868724756753 P47134 0.9512869715690612 0.9536849856376648 0.941340982913971 0.941340982913971 0.5525330305099487 0.572088897228241 0.4750197529792786 0.4750197529792786 48.34757915470232 40.0 1.0 no 6630 chrX_589631r 20301 essential YJR089W 1916 - CAACTTTTCCACTTATTGAT V|645|L V|645|I 0 1 0 0 -0.4361927665307621 P47134 0.9539830088615416 0.9574310183525084 0.4803602993488312 0.5986136794090271 41.69408009470135 30.0 1.0 no 6631 chrX_589751 20302 essential YJR089W 2033 + CTCAAGCGTTATTTCAACGC S|679|* S|679|L S|680|R silent|AGC>AGT|S|680 0 0 0 0 -1.7313177766523593 P47134 0.9298099875450134 0.9417110085487366 0.1964426338672638 0.06933373212814331 45.563403129582355 45.0 1.0 no 6632 chrX_589313 20303 essential YJR089W 1595 + GCAAATTGTAGATCAGAATT Q|533|E Q|533|* 0 0 0 0 0.4700821153551251 P47134 0.9590039849281312 37.099186834116104 30.0 1.0 no 6633 chrX_591862r 20306 high_effect YJR090C 2443 + AAACACTTGAAGATGCTCTT T|816|R T|816|I L|817|V L|817|F 0 0 0 0 0.31364224085612985 P24814 0.9373570084571838 1.003239989280701 0.96418297290802 0.9768720269203186 0.0574757419526577 0.3237292170524597 0.1940716654062271 0.2406283915042877 40.11620888935988 35.0 0.0 no 6634 chrX_591887r 20308 high_effect YJR090C 2418 + TCCAAGAATTTGATATTTAA silent|TCC>TCG|S|807 silent|TCC>TCT|S|807 S|807|C S|807|F 0 0 0 0 0.3199873711019488 P24814 0.8456869721412659 0.8741949796676636 0.010803762823343277 0.010258211754262449 33.885963845240376 20.0 0.0 no 6635 chrX_592068 20313 high_effect YJR090C 2240 - TGCAATACATCGTTATATCG C|753|S C|753|Y 0 0 0 0 0.09985687294862684 P24814 0.940962016582489 0.7728869915008545 0.11105083674192427 0.010026409290730951 40.22757160225984 35.0 0.0 no 6636 chrX_592067 20315 high_effect YJR090C 2241 - CTGCAATACATCGTTATATC C|753|S C|753|Y 0 0 0 0 0.20606268090824748 P24814 0.940962016582489 0.7728869915008545 0.11105083674192427 0.010026409290730951 40.60685245480829 35.0 0.0 no 6637 chrX_592142 20316 high_effect YJR090C 2166 - GACATTAGAAGCTCATATAT M|728|I M|728|I 0 0 0 0 -0.3060993438975048 P24814 0.9914019703865052 0.9914019703865052 0.16563649475574493 0.16563649475574493 38.27681549124213 30.0 0.0 no 6638 chrX_592260 20317 high_effect YJR090C 2048 - TCATTTGCGTACATTTGACA M|689|I M|689|I 0 0 0 0 0.05920320980219663 P24814 1.0305299758911133 1.0305299758911133 1.0 1.0 44.134192957499685 35.0 0.0 no 6639 chrX_592283r 20318 high_effect YJR090C 2022 + TTACCAAAATTAAAGAGAAT P|676|A P|676|S P|676|R P|676|L 0 0 0 0 -0.6232151078467679 P24814 0.9750660061836244 1.0015599727630615 0.9315940141677856 0.9387339949607848 0.048205476254224784 0.10867289453744887 0.042728401720523834 0.07868178933858871 29.841592989422 20.0 0.0 no 6640 chrX_592401r 20319 high_effect YJR090C 1904 + TTTCAATATAACTGATAACG F|636|L silent|TTC>TTT|F|636 0 0 0 0 0.1897081609291063 P24814 0.9833940267562866 0.4819847643375397 32.20459834901931 25.0 0.0 no 6641 chrX_592430r 20320 high_effect YJR090C 1875 + AACTTGCAAACAGTGCATTT N|626|K silent|AAC>AAT|N|626 Q|628|E Q|628|* 0 1 0 0 0.5976000048346402 P24814 0.9254990220069884 0.9944580197334291 0.07595451921224594 0.2258620709180832 42.070767846407705 35.0 0.0 no 6642 chrX_592476 20321 high_effect YJR090C 1832 - ACAACGATGCATCTGTAATT L|617|F silent|TTG>TTA|L|617 silent|TCG>TCC|S|616 silent|TCG>TCA|S|616 0 0 0 0 0.1891598527646836 P24814 0.8620190024375916 0.04700009897351265 41.01642054052047 35.0 0.0 no 6643 chrX_592687r 20324 high_effect YJR090C 1618 + TCACTAGGTTAGTTCAGCTG T|541|S T|541|I silent|CTC>CTG|L|540 silent|CTC>CTT|L|540 0 0 0 0 0.4566263786222857 P24814 1.003209948539734 0.98750901222229 0.32399728894233704 0.05242612212896347 49.0860509121747 45.0 0.0 no 6644 chrX_592689 20325 high_effect YJR090C 1619 - TCAGCTGAACTAACCTAGTG silent|CTG>CTC|L|546 silent|CTG>CTA|L|546 Q|545|H silent|CAG>CAA|Q|545 0 0 0 0 -0.16581539929043135 P24814 1.0004500150680542 0.15195780992507935 45.064454780033095 45.0 0.0 no 6645 chrX_592721 20326 high_effect YJR090C 1587 - AAACTAGAATCAGTGACATT S|535|T S|535|N 0 0 0 0 0.8142864067428209 P24814 0.9800959825515748 0.9490270018577576 0.07635179907083511 0.014854923821985722 35.9937032532942 30.0 0.0 no 6646 chrX_592755 20327 high_effect YJR090C 1553 - TATCGACCTCTACAAGCAAA D|524|H D|524|N V|523|L V|523|I 0 0 0 0 1.1627883094392997 P24814 0.9268940091133118 0.9540169835090636 1.014580011367798 1.0206899642944336 0.0133786303922534 0.10513290762901306 0.6995530128479004 0.327378511428833 42.82708876724604 40.0 0.0 no 6647 chrX_592839 20328 high_effect YJR090C 1469 - TTCTTTTCAACATCGGGGAA R|496|T R|496|K 0 0 0 0 -0.059719920789833125 P24814 0.8803939819335938 0.9247969985008241 0.07046549022197722 0.05556900799274445 44.69281585378832 40.0 0.0 no 6648 chrX_592897r 20329 high_effect YJR090C 1408 + GCTTTTATGTTCCTCAGGCA silent|GGC>GGG|G|470 silent|GGC>GGT|G|470 0 0 0 0 -0.28544618697373964 P24814 54.76405318145584 45.0 0.0 no 6649 chrX_592902r 20331 high_effect YJR090C 1403 + ACAGGGCTTTTATGTTCCTC Q|469|E Q|469|* silent|GGC>GGG|G|470 silent|GGC>GGT|G|470 0 0 0 0 -1.5902461032403234 P24814 0.9304490089416504 0.14175251126289368 52.50190270271162 45.0 0.0 no 6650 chrX_592910 20332 high_effect YJR090C 1398 - ACATAAAAGCCCTGTACTCT V|473|L V|473|I 0 0 0 0 0.4462244461583761 P24814 1.0085400342941284 1.0010900497436523 0.7349718809127808 0.2668424546718597 46.03989070011903 40.0 0.0 no 6651 chrX_592919r 20334 high_effect YJR090C 1386 + ACATATTGTCCCAGAGTACA T|463|R T|463|I 0 0 0 0 -0.531482305171979 P24814 1.00531005859375 0.9974380135536194 0.5255621671676636 0.10067152976989746 48.34757915470242 40.0 0.0 no 6652 chrX_593015 20336 high_effect YJR090C 1293 - CCTCTCAAAACAGCCGATAT R|437|T R|437|K G|438|R G|438|R 0 0 0 0 0.43541284961062776 P24814 0.9989600181579591 1.025689959526062 0.9392629861831664 0.9392629861831664 0.12104020267724992 0.6777563691139221 0.06465751677751541 0.06465751677751541 46.41488614628349 45.0 0.0 no 6653 chrX_593015r 20337 high_effect YJR090C 1290 + CCAATATCGGCTGTTTTGAG P|431|R P|431|L 0 0 0 0 -0.8057223137146857 P24814 0.9795129895210266 0.993932008743286 0.07877985388040543 0.16635164618492124 46.86997839905678 45.0 0.0 no 6654 chrX_593209r 20340 high_effect YJR090C 1096 + GTCAATTAGACTTGTTTTTA Q|367|E Q|367|* 0 0 0 0 0.4653887013455572 P24814 0.96035498380661 0.10657256841659546 38.69510802619317 25.0 0.0 no 6655 chrX_593284r 20341 high_effect YJR090C 1021 + TCCTTACCGTTTCCAAACTC L|342|V L|342|F F|341|L silent|TTC>TTT|F|341 0 0 0 0 0.3548115591091035 P24814 0.9954019784927368 0.9562429785728456 1.0135600566864014 0.035281088203191764 0.024987565353512764 0.6359496116638184 50.18486900961932 45.0 0.0 no 6656 chrX_593411 20344 high_effect YJR090C 897 - GTACATATGTTTTGATTTGA C|305|S C|305|Y 0 1 0 0 -0.4684887989125132 P24814 1.0216499567031858 0.9983950257301332 0.4998795986175537 1.0 38.35943228847498 25.0 0.0 no 6657 chrX_593563 20345 high_effect YJR090C 745 - CACTTGTTGACCTCTTAGCT V|255|L V|255|M 0 0 0 0 -0.2247132387471758 P24814 1.0114799737930298 0.8767619729042053 0.2258041054010391 0.04391361027956009 51.522201464972675 45.0 0.0 no 6658 chrX_593644r 20346 high_effect YJR090C 661 + ACATGGAAATTAGAAATTTA N|221|K silent|AAC>AAT|N|221 0 0 0 0 -0.2165443563411508 P24814 0.9537730216979979 0.08403531461954117 30.70191298211409 20.0 0.0 no 6659 chrX_593708 20347 high_effect YJR090C 600 - TGCAAATAACTAATTGCTTG L|206|F silent|TTG>TTA|L|206 0 1 0 0 1.0784699280987016 P24814 0.9067490100860596 35.997369385746765 30.0 0.0 no 6660 chrX_593709 20348 high_effect YJR090C 599 - GCAAATAACTAATTGCTTGT L|206|F silent|TTG>TTA|L|206 0 1 0 0 -0.4617971835881353 P24814 0.9067490100860596 38.155843613200034 30.0 0.0 no 6661 chrX_593840r 20351 high_effect YJR090C 465 + CACGAATTCAAGCTAATAGT H|156|Q silent|CAC>CAT|H|156 0 0 0 0 0.31502189928954905 P24814 1.0215599536895752 38.78070192106685 35.0 0.0 no 6662 chrX_593841r 20352 high_effect YJR090C 464 + CCACGAATTCAAGCTAATAG H|156|Q silent|CAC>CAT|H|156 H|156|D H|156|Y 0 0 0 0 -0.5179541486109436 P24814 1.0215599536895752 1.010210037231445 1.0228500366210938 40.18429358781378 40.0 0.0 no 6663 chrX_593868 20353 high_effect YJR090C 440 - GCTTCCGTTCTTCCTCTGGT K|153|N silent|AAG>AAA|K|153 silent|CGG>CGC|R|152 silent|CGG>CGA|R|152 0 0 0 0 0.3220002902227177 P24814 0.937973976135254 62.34818382639799 55.00000000000001 0.0 no 6664 chrX_594038r 20358 high_effect YJR090C 267 + ACGCTTTTGCCAACCAACAA L|91|V L|91|F T|90|R T|90|M 0 0 0 0 -0.9418170959136531 P24814 1.018939971923828 1.0400700569152832 0.904021978378296 0.831404983997345 48.2390806944627 45.0 0.0 no 6665 chrX_594082r 20360 high_effect YJR090C 223 + CAACGCTAAATAATATCTTT T|76|R T|76|M L|77|V silent|CTA>TTA|L|77 1 Series([], Name: modification, dtype: object) 0 0 0 0.0232044773832501 P24814 0.904021978378296 0.831404983997345 1.0171899795532229 34.403963298385804 25.0 0.0 no 6666 chrX_594140 20362 high_effect YJR090C 168 - GCCGTTTCTCTAGTTCGTGA silent|ACG>ACC|T|62 silent|ACG>ACA|T|62 A|63|P A|63|T 0 0 0 0 0.7241596476374295 P24814 0.9923409819602966 1.0361399650573728 55.31249947221318 50.0 0.0 no 6667 chrX_594233 20363 high_effect YJR090C 75 - CTACTATTCAGCCACAATTG S|31|T S|31|N 0 0 0 0 0.16684928064947546 P24814 0.9792150259017944 0.9489039778709412 44.12705536467041 40.0 0.0 no 6668 chrX_594234 20364 high_effect YJR090C 74 - TACTATTCAGCCACAATTGA S|31|T S|31|N 0 0 0 0 1.4185519718921449 P24814 0.9792150259017944 0.9489039778709412 43.529888575611274 35.0 0.0 no 6669 chrX_594257 20366 high_effect YJR090C 51 - CCCAAATTTGGATGTATATC L|23|F silent|TTG>TTA|L|23 G|24|R G|24|S 0 0 0 0 0.7017400781043106 P24814 0.9311789870262146 0.8052539825439453 0.9205039739608764 41.83139606717509 35.0 0.0 no 6670 chrX_594257r 20368 high_effect YJR090C 48 + CCTGATATACATCCAAATTT P|17|R P|17|L 0 0 0 0 -0.9080390147085776 P24814 0.8449479937553406 0.904717981815338 40.647984072183476 30.0 0.0 no 6671 chrX_594285 20369 high_effect YJR090C 23 - GCAGCCTATTGCTGTCATTG silent|CTG>CTC|L|14 silent|CTG>CTA|L|14 R|13|S silent|AGG>AGA|R|13 0 0 0 0 -0.19576211274176736 P24814 0.9045770168304444 54.220473364744244 50.0 0.0 no 6672 chrX_603477 20370 essential YJR093C 707 - TCAACTTCCCTTGCTGTTGG L|242|F silent|TTG>TTA|L|242 K|241|N silent|AAG>AAA|K|241 FIP1 Factor Interacting with Poly(A) polymerase 327.0 0 0 0 0 -0.1348603355200007 P45976 0.0 0.013558072037994863 53.97937554790713 50.0 0.0 no 6673 chrX_603506 20372 essential YJR093C 678 - AGGCCCATTAGGATCCTCCT G|232|A G|232|D G|232|R G|232|S FIP1 Factor Interacting with Poly(A) polymerase 327.0 0 0 0 0 -3.3325730349719733 P45976 0.027442634105682373 0.06566925346851349 0.012029370293021202 0.042439088225364685 60.965049766527216 55.00000000000001 0.0 yes 6674 chrX_603523r 20375 essential YJR093C 658 + TACAACAAGATTATAATCCT Q|221|E Q|221|* Q|222|E Q|222|* FIP1 Factor Interacting with Poly(A) polymerase 327.0 0 1 0 0 -0.26712473199528897 P45976 0.08186985552310944 0.8130765557289124 35.344330012889365 25.0 0.0 no 6675 chrX_603556 20376 essential YJR093C 628 - TCTATGTAAATACTCCATCC R|216|T R|216|K FIP1 Factor Interacting with Poly(A) polymerase 327.0 0 1 0 0 0.34570907821071456 P45976 0.02324127778410912 0.5966694355010986 43.08644968093154 35.0 0.0 no 6676 chrX_603745 20379 essential YJR093C 439 - ATCGCTCTCTGTAGCTTTTA D|153|H D|153|N S|152|T S|152|N FIP1 Factor Interacting with Poly(A) polymerase 327.0 0 1 0 0 -0.18558264336823194 P45976 0.12626366317272186 0.4945733845233917 0.7096378207206726 0.3932871222496033 50.69474154165573 40.0 0.0 no 6677 chrX_603942 20383 essential YJR093C 242 - CCAGACTTATGATAACCTCT silent|CTG>CTC|L|87 silent|CTG>CTA|L|87 S|86|T S|86|N FIP1 Factor Interacting with Poly(A) polymerase 327.0 0 0 0 0 -2.0608844591123483 P45976 0.0931667760014534 0.09931318461894988 45.626954128856255 40.0 0.0 yes 6678 chrX_603942r 20384 essential YJR093C 239 + CCTAGAGGTTATCATAAGTC L|81|V silent|CTA>TTA|L|81 FIP1 Factor Interacting with Poly(A) polymerase 327.0 0 1 0 0 -0.1434717068479845 P45976 1.0 44.047820677866696 40.0 0.0 no 6679 chrX_604006 20385 essential YJR093C 178 - TTCATCAGAACGATCATCTC E|66|Q E|66|K D|65|H D|65|N FIP1 Factor Interacting with Poly(A) polymerase 327.0 0 0 0 0 0.3278716170417565 P45976 0.30964991450309753 0.3932400643825531 0.08222535252571106 0.5959857106208801 42.762496624365895 40.0 0.0 no 6680 chrX_604047r 20386 essential YJR093C 134 + GCAAAAATTCGACTCTCCCG Q|46|E Q|46|* FIP1 Factor Interacting with Poly(A) polymerase 327.0 0 1 0 0 1.0342379507561408 P45976 1.0 46.459642039261034 50.0 0.0 no 6681 chrX_604118 20387 essential YJR093C 66 - TCTCTTGATCGTTTAGATGA R|28|T R|28|K D|29|H D|29|N FIP1 Factor Interacting with Poly(A) polymerase 327.0 0 1 0 0 -1.3228244258259916 P45976 0.6077620983123779 1.0 0.16743896901607513 0.4963548481464386 43.417441779024564 35.0 0.0 no 6682 chrX_637040 20388 essential YJR112W 10 + CACATGGAATACGGTATATT H|5|D H|5|Y NNF1 Necessary for Nuclear Function 201.0 0 0 0 0 0.06226076519918845 P47149 0.5151789188385011 0.16656671464443207 39.845622879523894 35.0 1.0 no 6683 chrX_637092r 20391 essential YJR112W 65 - TCTGTAATTTCGAAATCGAT Q|28|H silent|CAG>CAA|Q|28 NNF1 Necessary for Nuclear Function 201.0 0 0 0 0 1.0047257628558104 P47149 0.2126669138669968 37.386098124791204 30.0 1.0 no 6684 chrX_637140r 20392 essential YJR112W 113 - GCTTGCTATTCACATATTGC K|44|N silent|AAG>AAA|K|44 S|43|T S|43|N NNF1 Necessary for Nuclear Function 201.0 1 Series([], Name: modification, dtype: object) 0 0 0 -1.0794979303153378 P47149 0.4926167726516724 1.0 0.1299862563610077 47.6597351286884 40.0 1.0 no 6685 chrX_637143 20393 essential YJR112W 113 + GCAATATGTGAATAGCAAGC Q|39|E Q|39|* NNF1 Necessary for Nuclear Function 201.0 0 0 0 0 -1.1651939097789106 P47149 0.9824868440628052 41.067380958799454 40.0 1.0 no 6686 chrX_637194r 20396 essential YJR112W 167 - CCGTCCAGAATTCCGTTAAT silent|ACG>ACC|T|62 silent|ACG>ACA|T|62 W|61|C W|61|* NNF1 Necessary for Nuclear Function 201.0 0 0 0 0 -0.14866698095074227 P47149 0.005844666622579098 49.24974253251395 45.0 1.0 no 6687 chrX_637392r 20399 essential YJR112W 365 - GCATCCGTTGGCTGTATAAA M|128|I M|128|I silent|CGG>CGC|R|127 silent|CGG>CGA|R|127 NNF1 Necessary for Nuclear Function 201.0 0 0 0 0 -0.5630428060716515 P47149 0.23592853546142575 0.23592853546142575 49.07988898317518 45.0 1.0 no 6688 chrX_637475r 20401 essential YJR112W 448 - CTCTAAGTCTTTCAACTCCT E|156|Q E|156|K NNF1 Necessary for Nuclear Function 201.0 0 0 0 0 0.7607928345991632 P47149 0.5543572306632996 0.2475496381521225 47.49686078721379 40.0 1.0 no 6689 chrX_637418r 20403 essential YJR112W 391 - CCGCTCGTCTATCTCGTGTA E|136|D silent|GAG>GAA|E|136 R|137|P R|137|Q NNF1 Necessary for Nuclear Function 201.0 0 0 0 0 0.5539561481192347 P47149 0.596453070640564 0.014465751126408575 0.042602766305208206 56.25181272858725 55.00000000000001 1.0 no 6690 chrX_652102 20405 essential YJR123W 201 + ATCTTTGTTGCTCACACCGC I|68|M silent|ATC>ATT|I|68 RPS5 Ribosomal Protein of the Small subunit 225.0 0 0 0 0 0.1672460274513389 P26783 0.22840723395347595 0.12894000113010404 54.141404953720844 50.0 1.0 no 6691 chrX_652206 20407 essential YJR123W 305 + AAACAACGGTAAGAAATTAA N|103|K silent|AAC>AAT|N|103 N|104|K silent|AAC>AAT|N|104 RPS5 Ribosomal Protein of the Small subunit 225.0 0 0 0 0 0.0017702112682415059 P26783 0.009130708873271942 0.14278939366340634 -0.4905200004577637 -0.7685800194740295 30.088401042654933 25.0 1.0 no 6692 chrX_652278r 20408 essential YJR123W 380 - CAACAACTTGGATTGGGTTT V|133|L V|133|I V|132|L V|132|I RPS5 Ribosomal Protein of the Small subunit 225.0 0 0 0 0 -0.44418662094891176 P26783 1.0 0.07136958837509155 0.10148610919713974 0.14622862637043 -2.8534998893737797 -0.7770599722862244 -1.6706800460815432 -0.6055200099945068 43.50751679507693 40.0 1.0 no 6693 chrX_652284r 20409 essential YJR123W 386 - CGTCAACAACAACTTGGATT D|135|H D|135|N V|134|L V|134|I RPS5 Ribosomal Protein of the Small subunit 225.0 0 0 0 0 -0.8907536372345931 P26783 0.04460366070270538 0.6174077391624451 0.04505641385912895 0.08195094764232635 -0.3390200138092041 -0.5867400169372559 -1.922659993171692 -1.2740199565887451 40.95338589325638 40.0 1.0 no 6694 chrX_652340r 20415 essential YJR123W 442 - AGCACCACCACCACCGACTC A|154|P A|154|T G|153|A G|153|D RPS5 Ribosomal Protein of the Small subunit 225.0 0 0 0 0 -1.4858210886720895 P26783 0.027152175083756447 1.0 0.02517075277864933 0.006200924981385469 0.31742000579833984 0.048920001834630966 -0.24130000174045566 -0.14166000485420227 59.69918190093637 65.0 1.0 no 6695 chrX_652390r 20416 essential YJR123W 492 - GCTTGGTTAACTCTTCTCAA A|171|P A|171|T RPS5 Ribosomal Protein of the Small subunit 225.0 0 0 0 0 -0.8911124171795277 P26783 0.004949610214680432 0.00344501412473619 5.426080226898193 3.762200117111206 47.07742472118605 40.0 1.0 no 6696 chrX_696164 20420 essential YJR141W 258 + TCTATCATGTCGCTTCCAGA S|87|C S|87|F I|88|M silent|ATC>ATT|I|88 IPA1 Important for cleavage and PolyAdenylation 347.0 0 0 0 0 -0.9411618177259468 P47172 0.041617441922426224 0.04167058691382408 0.3220056593418121 51.92872961049835 45.0 1.0 no 6697 chrX_696179r 20422 essential YJR141W 276 - TCTTTAGTCCATCTTCCATC E|99|Q E|99|K IPA1 Important for cleavage and PolyAdenylation 347.0 0 0 0 0 0.5557179668820631 P47172 0.07474810630083084 1.0 51.50250650293464 40.0 1.0 no 6698 chrX_696334 20423 essential YJR141W 428 + TTGCCACAAACCCGATGTTA C|144|W silent|TGC>TGT|C|144 H|145|D H|145|Y IPA1 Important for cleavage and PolyAdenylation 347.0 0 0 0 0 -0.9805961942749106 P47172 0.0 0.0 0.0 49.224992395959816 45.0 1.0 no 6699 chrX_696344r 20424 essential YJR141W 441 - GACTTGTCTTCCTTAACATC K|153|N silent|AAG>AAA|K|153 IPA1 Important for cleavage and PolyAdenylation 347.0 0 0 0 0 0.4963428286865755 P47172 0.07224756479263306 46.188497572358024 40.0 1.0 no 6700 chrX_696337r 20425 essential YJR141W 434 - CTTCCTTAACATCGGGTTTG E|151|Q E|151|K K|150|N silent|AAG>AAA|K|150 IPA1 Important for cleavage and PolyAdenylation 347.0 0 0 0 0 -0.6440378539236058 P47172 0.4110408127307892 0.5848087668418884 0.5191747546195984 47.870392328666924 45.0 1.0 no 6701 chrX_696345r 20426 essential YJR141W 442 - AGACTTGTCTTCCTTAACAT K|153|N silent|AAG>AAA|K|153 IPA1 Important for cleavage and PolyAdenylation 347.0 0 0 0 0 0.5576428267166144 P47172 0.07224756479263306 45.21349932944901 35.0 1.0 no 6702 chrX_696369r 20427 essential YJR141W 466 - TAGCGTTTCAAATCTTGTGT silent|ACG>ACC|T|161 silent|ACG>ACA|T|161 IPA1 Important for cleavage and PolyAdenylation 347.0 0 0 0 0 0.3026190662262441 P47172 43.99848553614065 35.0 1.0 no 6703 chrX_696560 20429 essential YJR141W 654 + AAACTGCAGTTAATACGCAG L|220|V silent|CTG>TTG|L|220 Q|221|E Q|221|* IPA1 Important for cleavage and PolyAdenylation 347.0 0 0 0 0 -2.0303327282577865 P47172 0.2431258112192154 0.4606974720954895 40.60878139023804 40.0 1.0 yes 6704 chrX_696678 20430 essential YJR141W 772 + AAACGGAATCATTGCTAGTT T|259|R T|259|M IPA1 Important for cleavage and PolyAdenylation 347.0 0 0 0 0 0.4484035424732952 P47172 0.5017633438110352 0.10138198733329773 40.50384224162457 35.0 1.0 no 6705 chrXI_34582 20432 high_effect YKL212W 39 + ATCTTCTTCAAGCTTGCTGA I|14|M silent|ATC>ATT|I|14 F|15|L silent|TTC>TTT|F|15 SAC1 Suppressor of ACtin 623.0 0 0 0 0 1.1247706821974852 P32368 0.9598389863967896 0.9387490153312684 0.0575576052069664 0.619576632976532 0.01841999962925911 2.674760103225708 0.7753999829292297 48.83475145444163 40.0 1.0 no 6706 chrXI_34630 20433 high_effect YKL212W 87 + CACTTGGCCAATCAAGATCA H|30|Q silent|CAC>CAT|H|30 SAC1 Suppressor of ACtin 623.0 0 0 0 0 0.06125237496692679 P32368 0.9588389992713928 0.6073784828186035 1.4225599765777588 46.975459626184254 45.0 1.0 no 6707 chrXI_34614 20434 high_effect YKL212W 71 + TAACGATGCTGTTATTCACT N|25|K silent|AAC>AAT|N|25 SAC1 Suppressor of ACtin 623.0 0 1 0 0 0.5758774047920004 P32368 0.9439849853515624 0.7436789274215698 -0.13991999626159668 42.585940341648275 35.0 1.0 no 6708 chrXI_34724 20438 high_effect YKL212W 181 + TCATTAAGCTAAAGTTGAAC F|61|L silent|TTC>TTT|F|61 SAC1 Suppressor of ACtin 623.0 0 0 0 0 0.673209263679729 P32368 0.9387490153312684 0.3589894473552704 2.8859798908233643 34.934799876458214 30.0 1.0 no 6709 chrXI_34712r 20439 high_effect YKL212W 172 - TAGCTTAATGAACCCCATCA K|63|N silent|AAG>AAA|K|63 SAC1 Suppressor of ACtin 623.0 0 0 0 0 -0.1816019743487916 P32368 0.9355990290641784 0.05416439473628998 0.28922000527381897 1.1316800117492676 47.43980245245746 40.0 1.0 no 6710 chrXI_34778r 20441 high_effect YKL212W 238 - AACGTGGCCATTGAATCTAC V|86|L V|86|I SAC1 Suppressor of ACtin 623.0 0 0 0 0 0.08954335129329691 P32368 0.9539830088615416 0.9574310183525084 0.32347816228866577 0.20013481378555295 0.2015399932861328 -0.3035599887371063 -0.06379999965429306 0.004600000102072954 45.666443277325975 45.0 1.0 no 6711 chrXI_34835r 20443 high_effect YKL212W 295 - ATCGATTCTCGAGTTAAACT D|105|H D|105|N SAC1 Suppressor of ACtin 623.0 0 0 0 0 1.263577870459598 P32368 0.9486550092697144 0.956179976463318 0.011037204414606094 0.15911929309368136 4.1174798011779785 2.8620200157165527 40.79852741596704 35.0 1.0 no 6712 chrXI_34991r 20449 high_effect YKL212W 451 - CCAAAAGAATCGTTCATCAG W|157|S W|157|* SAC1 Suppressor of ACtin 623.0 0 0 0 0 -0.32084268900174473 P32368 0.8858469724655151 0.0 6.282279968261719 7.121300220489503 39.662347505713 40.0 1.0 no 6713 chrXI_35153 20452 high_effect YKL212W 610 + TTACCAGACGTAGTATATTT T|205|S T|205|I silent|ACC>ACG|T|205 silent|ACC>ACT|T|205 SAC1 Suppressor of ACtin 623.0 0 0 0 0 -0.1369213103763084 P32368 0.9491789937019348 0.9472420215606691 0.15037763118743894 0.005890596657991409 1.8818199634552 2.9945199489593506 41.42712369041095 30.0 1.0 no 6714 chrXI_35193r 20456 high_effect YKL212W 653 - CGTCTTTGTCAACACCACGA D|224|H D|224|N SAC1 Suppressor of ACtin 623.0 0 0 0 0 0.5474406899356279 P32368 0.9486550092697144 0.956179976463318 0.17859995365142822 0.13722404837608335 0.08117999881505966 -0.1431799978017807 49.52915447197876 50.0 1.0 no 6715 chrXI_35290 20457 high_effect YKL212W 747 + TTCTCCTTCTTACAGACAAG F|250|L silent|TTC>TTT|F|250 S|251|C S|251|F SAC1 Suppressor of ACtin 623.0 0 1 0 0 0.4413583856111151 P32368 0.9387490153312684 0.945252001285553 0.9294660091400146 0.3541966378688812 0.0048951045610010615 0.0025705206207931037 2.620419979095459 0.7057999968528748 9.050200462341307 45.056541408733146 40.0 1.0 no 6716 chrXI_35469r 20460 high_effect YKL212W 929 - CCTCTTTCACGGGTAGTTCG E|316|Q E|316|K E|316|D silent|GAG>GAA|E|316 SAC1 Suppressor of ACtin 623.0 0 0 0 0 -1.7434086372760564 P32368 0.956179976463318 0.9475290179252625 0.94931298494339 0.5995520353317261 0.9490745663642884 0.618313193321228 -0.36625999212265015 -1.2430800199508667 0.3472599983215332 54.098062099388464 55.00000000000001 1.0 no 6717 chrXI_35709 20462 high_effect YKL212W 1166 + AACAAACTGTATGGATTGTT T|390|R T|390|I N|391|K silent|AAC>AAT|N|391 SAC1 Suppressor of ACtin 623.0 0 0 0 0 0.34334778706239955 P32368 0.9476869702339172 0.9472420215606691 0.9439849853515624 0.0 0.0 0.0 1.1566799879074097 -1.550860047340393 2.1613800525665283 37.56357034214818 30.0 1.0 no 6718 chrXI_35747 20463 high_effect YKL212W 1204 + TTCAATCTGTTTTAGCCCAG Q|403|E Q|403|* S|404|C S|404|F SAC1 Suppressor of ACtin 623.0 0 0 0 0 0.7011609922760617 P32368 0.9590039849281312 0.945252001285553 0.9294660091400146 0.0 0.0 0.0 -1.3840600252151491 -0.4494999945163727 3.33624005317688 48.66991214765693 40.0 1.0 no 6719 chrXI_35748 20464 high_effect YKL212W 1205 + TCAATCTGTTTTAGCCCAGT Q|403|E Q|403|* S|404|C S|404|F SAC1 Suppressor of ACtin 623.0 0 0 0 0 -0.05128605965910017 P32368 0.9590039849281312 0.945252001285553 0.9294660091400146 0.0 0.0 0.0 -1.3840600252151491 -0.4494999945163727 3.33624005317688 51.1048349606586 40.0 1.0 no 6720 chrXI_35801 20466 high_effect YKL212W 1258 + TCGTTGCTACTGGAAGCACT silent|GTC>GTG|V|420 silent|GTC>GTT|V|420 A|422|G A|422|V SAC1 Suppressor of ACtin 623.0 0 0 0 0 0.2012769801099417 P32368 0.9484469890594482 0.9504740238189696 0.3826560080051422 0.2833163142204285 0.2483000010251999 0.6819400191307068 0.15299999713897705 1.0989999771118164 50.76306351411421 50.0 1.0 no 6721 chrXI_35843 20467 high_effect YKL212W 1300 + TAACTTCTTACCAAAACTTA T|435|S T|435|I S|436|C S|436|F SAC1 Suppressor of ACtin 623.0 0 0 0 0 0.2279808527448714 P32368 0.9491789937019348 0.9472420215606691 0.945252001285553 0.9294660091400146 0.5861204266548157 0.4707300066947937 0.185739740729332 0.7460613250732422 -0.18941999971866608 -0.8464199900627136 0.3229599893093109 -0.8920000195503235 35.92179261219286 25.0 1.0 no 6722 chrXI_39191r 20472 essential YKL210W 31 - ACTTTCATCGATTTCTCCGG S|17|T S|17|N E|16|Q E|16|K UBA1 UBiquitin Activating 1024.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.21651786302505494 P22515 0.9512869715690612 0.9536849856376648 0.956179976463318 0.9475290179252625 0.02913696691393852 0.05933735147118568 0.008569754660129547 0.006643330212682486 49.402915358388945 45.0 1.0 no 6723 chrXI_39219 20473 essential YKL210W 56 + TTCTCGTCAACTTTATGTGT S|20|C S|20|F R|21|G R|21|C UBA1 UBiquitin Activating 1024.0 0 1 0 0 -0.8017974221954074 P22515 0.945252001285553 0.9294660091400146 0.8994590044021606 0.8926740288734436 0.0016914441948756573 0.0010723834857344627 0.002967716194689274 0.0003756224759854376 45.09450284200637 35.0 1.0 no 6724 chrXI_39220 20474 essential YKL210W 57 + TCTCGTCAACTTTATGTGTT R|21|G R|21|C S|20|C S|20|F UBA1 UBiquitin Activating 1024.0 0 1 0 0 -4.002270938144939 P22515 0.8994590044021606 0.8926740288734436 0.945252001285553 0.9294660091400146 0.002967716194689274 0.0003756224759854376 0.0016914441948756573 0.0010723834857344627 45.09450284200643 35.0 1.0 yes 6725 chrXI_39225 20475 essential YKL210W 62 + TCAACTTTATGTGTTGGGTA Q|22|E Q|22|* L|23|V L|23|F UBA1 UBiquitin Activating 1024.0 0 1 0 0 -1.085886695457548 P22515 0.9590039849281312 0.9512209892272948 0.9587849974632264 0.010273268446326256 0.012897934764623642 0.011401576921343805 44.27431276479222 35.0 1.0 no 6726 chrXI_39268 20476 essential YKL210W 105 + ACCTCCAACGTATTAATTCT silent|ACC>ACG|T|36 silent|ACC>ACT|T|36 T|36|S T|36|I UBA1 UBiquitin Activating 1024.0 0 0 0 0 0.1388664508310739 P22515 0.9491789937019348 0.9472420215606691 0.7859203219413757 0.08562670648097992 0.08669999986886978 0.06020000204443932 44.82727741813403 35.0 1.0 no 6727 chrXI_39269r 20477 essential YKL210W 109 - GCCGAGAATTAATACGTTGG G|43|R G|43|S G|43|A G|43|D UBA1 UBiquitin Activating 1024.0 0 0 0 0 -1.1831530297900779 P22515 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 43.505175344647284 45.0 1.0 no 6728 chrXI_39363r 20481 essential YKL210W 203 - CTGCCAATTGAACCGGCTCA A|74|P A|74|T L|73|F silent|TTG>TTA|L|73 UBA1 UBiquitin Activating 1024.0 0 0 0 0 -0.3536086268042209 P22515 0.9573720097541808 0.9523990154266356 0.9587849974632264 0.2874756753444672 0.5882999897003174 0.5895215272903442 53.06191981780836 55.00000000000001 1.0 no 6729 chrXI_39364r 20482 essential YKL210W 204 - TCTGCCAATTGAACCGGCTC D|75|H D|75|N A|74|P A|74|T UBA1 UBiquitin Activating 1024.0 0 0 0 0 -0.4331261428768284 P22515 0.9486550092697144 0.956179976463318 0.9573720097541808 0.9523990154266356 0.042123768478631966 0.06500206887722015 0.2874756753444672 0.5882999897003174 52.98981367844028 55.00000000000001 1.0 no 6730 chrXI_39446r 20483 essential YKL210W 286 - CAACTCTGCCAATTTGGCTC E|101|D silent|GAG>GAA|E|101 E|101|Q E|101|K UBA1 UBiquitin Activating 1024.0 0 0 0 0 -0.04504952819618577 P22515 0.94931298494339 0.956179976463318 0.9475290179252625 0.081793412566185 0.016640542075037956 0.01500375848263502 50.608892257810275 50.0 1.0 no 6731 chrXI_39452r 20484 essential YKL210W 292 - TGCGTTCAACTCTGCCAATT A|104|P A|104|T L|102|F silent|TTG>TTA|L|102 UBA1 UBiquitin Activating 1024.0 0 0 0 0 -0.32484462683468274 P22515 0.9573720097541808 0.9523990154266356 0.9587849974632264 0.3407096564769745 0.2526818811893463 0.0 50.02248293647949 45.0 1.0 no 6732 chrXI_39543 20487 essential YKL210W 380 + CGCTACGGACACTGTTTCTT A|128|G A|128|V T|129|R T|129|M UBA1 UBiquitin Activating 1024.0 0 0 0 0 1.0145786688938268 P22515 0.9484469890594482 0.9504740238189696 0.9476869702339172 0.9502379894256592 0.014592504128813744 0.6798086762428284 0.016336094588041306 0.04298113286495209 50.618386208213046 50.0 1.0 no 6733 chrXI_39552 20488 essential YKL210W 389 + CACTGTTTCTTTGGAAGATA T|131|S T|131|I UBA1 UBiquitin Activating 1024.0 0 0 0 0 -0.03143391820534647 P22515 0.9491789937019348 0.9472420215606691 1.0 0.17346902191638947 41.89342449162183 35.0 1.0 no 6734 chrXI_39620r 20491 essential YKL210W 460 - AAACAGCCCTCTTGTCTCCG silent|CTG>CTC|L|159 silent|CTG>CTA|L|159 silent|GGG>GGC|G|158 silent|GGG>GGA|G|158 UBA1 UBiquitin Activating 1024.0 0 0 0 0 0.8112459374295771 P22515 55.06856813481494 55.00000000000001 1.0 no 6735 chrXI_39660r 20494 essential YKL210W 500 - ACACTGTGAACTCGTCACCT V|173|L V|173|M silent|GTG>GTC|V|173 silent|GTG>GTA|V|173 UBA1 UBiquitin Activating 1024.0 0 0 0 0 -0.7876044771935573 P22515 0.9539830088615416 0.9587630033493042 0.12324469536542892 0.006104464642703533 50.7634838838668 50.0 1.0 no 6736 chrXI_39672 20495 essential YKL210W 509 + GTTCACAGTGTTGGACCCAA F|171|L silent|TTC>TTT|F|171 T|172|R T|172|I UBA1 UBiquitin Activating 1024.0 0 0 0 0 -0.048501470417925824 P22515 0.9387490153312684 0.9476869702339172 0.9472420215606691 0.09265519678592682 0.034482698887586594 0.4496936798095703 53.072554196894544 50.0 1.0 no 6737 chrXI_39703r 20500 essential YKL210W 543 - TCTGAAACCATACCAGTGCG D|188|H D|188|N UBA1 UBiquitin Activating 1024.0 0 1 0 0 0.9474783680095056 P22515 0.9486550092697144 0.956179976463318 0.2727580070495605 0.552464485168457 48.00461364436836 50.0 1.0 no 6738 chrXI_39751 20503 essential YKL210W 588 + ATGCTAGATGATAACAGACA L|198|V silent|CTA>TTA|L|198 UBA1 UBiquitin Activating 1024.0 0 0 0 0 0.5376022604892849 P22515 0.9512209892272948 0.3873555660247803 39.39558775948376 35.0 1.0 no 6739 chrXI_39752 20504 essential YKL210W 589 + TGCTAGATGATAACAGACAC L|198|V silent|CTA>TTA|L|198 UBA1 UBiquitin Activating 1024.0 0 0 0 0 0.8329639892649034 P22515 0.9512209892272948 0.3873555660247803 39.821288722975225 40.0 1.0 no 6740 chrXI_39793 20506 essential YKL210W 630 + GTCAGGTTCTCCGAAGTAGA silent|GTC>GTG|V|211 silent|GTC>GTT|V|211 UBA1 UBiquitin Activating 1024.0 0 0 0 0 0.18541842313583867 P22515 51.54927919043894 50.0 1.0 no 6741 chrXI_39815 20507 essential YKL210W 652 + GTCTTGATAAGTTGAATGAT L|219|V L|219|F UBA1 UBiquitin Activating 1024.0 0 0 0 0 0.5337220878710011 P22515 0.9512209892272948 0.9587849974632264 0.015419183298945429 0.05811959877610207 37.54998029442498 30.0 1.0 no 6742 chrXI_39840 20508 essential YKL210W 677 + CCTTTTTAAAGTTGAGGTTT L|227|V L|227|F UBA1 UBiquitin Activating 1024.0 0 0 0 0 0.2509843103169616 P22515 0.9512209892272948 0.9587849974632264 0.01333780772984028 0.0032295652199536558 2.9811999797821045 2.0742998123168945 41.85005990297896 30.0 1.0 no 6743 chrXI_39840r 20509 essential YKL210W 680 - CCAAAACCTCAACTTTAAAA L|233|F silent|TTG>TTA|L|233 V|232|L V|232|I UBA1 UBiquitin Activating 1024.0 0 0 0 0 -0.016059263183899913 P22515 0.9587849974632264 0.9539830088615416 0.9574310183525084 0.34925222396850586 0.03120394237339497 0.13133421540260315 36.022388831971966 30.0 1.0 no 6744 chrXI_39944r 20513 essential YKL210W 784 - AGACTTGAATGAGATTTTAC K|267|N silent|AAG>AAA|K|267 UBA1 UBiquitin Activating 1024.0 0 1 0 0 0.5142350351172091 P22515 0.9355990290641784 0.036396563053131104 35.801489011089075 30.0 1.0 no 6745 chrXI_40093r 20515 essential YKL210W 933 - TCTTCGTCATTCATTGTTCT D|318|H D|318|N E|317|Q E|317|K UBA1 UBiquitin Activating 1024.0 0 0 0 0 0.8952143266407766 P22515 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.04771192744374275 0.03982393816113472 0.5117729902267456 0.7046002149581909 48.006823490920674 35.0 1.0 no 6746 chrXI_40162r 20518 essential YKL210W 1002 - ACACCTTCACCCAGAACCTC G|340|A G|340|D V|341|L V|341|I UBA1 UBiquitin Activating 1024.0 0 0 0 0 0.6606182187688519 P22515 0.9499930143356324 0.9446240067481996 0.9539830088615416 0.9574310183525084 0.9201956391334534 0.6933738589286804 0.3085457980632782 0.1919372081756592 55.38385705550906 55.00000000000001 1.0 no 6747 chrXI_40203 20519 essential YKL210W 1040 + AATCAAAGAGCTTTCCTATC I|348|M silent|ATC>ATT|I|348 UBA1 UBiquitin Activating 1024.0 0 0 0 0 0.7376086299533391 P22515 0.9598389863967896 0.06935229152441025 41.37271045067649 35.0 1.0 no 6748 chrXI_40240r 20523 essential YKL210W 1080 - CCGAAAAATGCTACGACACC G|367|R G|367|S UBA1 UBiquitin Activating 1024.0 0 0 0 0 -0.3802180140132191 P22515 0.941340982913971 0.951104998588562 0.002720559714362025 0.009189488366246223 43.49807640898052 50.0 1.0 no 6749 chrXI_40251 20524 essential YKL210W 1088 + AGCATTTTTCGGTGGCCTTG A|364|G A|364|V UBA1 UBiquitin Activating 1024.0 0 0 0 0 -0.07882269982836967 P22515 0.9484469890594482 0.9504740238189696 0.11756761372089385 0.007294374518096447 54.48794894980301 50.0 1.0 no 6750 chrXI_40407 20525 essential YKL210W 1244 + TCGTTACGATAATCAAATCG R|416|G R|416|C Y|417|* silent|TAC>TAT|Y|417 UBA1 UBiquitin Activating 1024.0 0 0 0 0 0.6197831519953917 P22515 0.8994590044021606 0.8926740288734436 0.0 0.0 36.965302944942096 35.0 1.0 no 6751 chrXI_40493r 20528 essential YKL210W 1333 - TTTCAACATCTCACAACCAA L|450|F silent|TTG>TTA|L|450 M|449|I M|449|I UBA1 UBiquitin Activating 1024.0 0 0 0 0 0.15875674927481928 P22515 0.9587849974632264 0.9553959965705872 0.9553959965705872 0.0074297478422522545 0.040552183985710144 0.040552183985710144 41.867628530007146 35.0 1.0 no 6752 chrXI_40605 20532 essential YKL210W 1442 + TCAGTTCTTGTTTAGACCAA Q|482|E Q|482|* F|483|L silent|TTC>TTT|F|483 UBA1 UBiquitin Activating 1024.0 0 0 0 0 0.7830463617266921 P22515 0.9590039849281312 0.9387490153312684 0.007658777758479118 0.05451056361198425 45.311647120232685 35.0 1.0 no 6753 chrXI_40672 20534 essential YKL210W 1509 + GCTATGAACCCCGATTTGAA A|504|G A|504|V UBA1 UBiquitin Activating 1024.0 0 0 0 0 0.6728484803134679 P22515 0.9484469890594482 0.9504740238189696 0.3776862025260925 0.2756395637989044 47.996216509174424 45.0 1.0 no 6754 chrXI_40939r 20538 essential YKL210W 1779 - CACAATGGGATAGACTTTTC L|599|F silent|TTG>TTA|L|599 UBA1 UBiquitin Activating 1024.0 0 1 0 0 -0.8433067189025112 P22515 0.9587849974632264 0.029297655448317524 41.52006797328386 40.0 1.0 no 6755 chrXI_41158r 20546 essential YKL210W 1998 - ATACAATCTTCAAAATTGTG C|672|S C|672|Y UBA1 UBiquitin Activating 1024.0 0 1 0 0 0.8951998990954585 P22515 0.9421560168266296 0.9290120005607604 0.0 0.0 33.14027419557891 25.0 1.0 no 6756 chrXI_41269 20547 essential YKL210W 2106 + AACGGTGAACCATTTTGGTC N|703|K silent|AAC>AAT|N|703 UBA1 UBiquitin Activating 1024.0 0 0 0 0 -0.6077627965504285 P22515 0.9439849853515624 0.02547558397054672 46.18753715263818 45.0 1.0 no 6757 chrXI_41264 20548 essential YKL210W 2101 + CTTCCAACGGTGAACCATTT S|702|C S|702|F silent|TCC>TCG|S|702 silent|TCC>TCT|S|702 UBA1 UBiquitin Activating 1024.0 0 0 0 0 0.16306821041729594 P22515 0.945252001285553 0.9294660091400146 0.004888249561190604 0.002594501711428165 48.005993772751886 45.0 1.0 no 6758 chrXI_41341 20550 essential YKL210W 2178 + CACTTCCATTTTGTCGTAGC H|727|Q silent|CAC>CAT|H|727 F|728|L silent|TTC>TTT|F|728 UBA1 UBiquitin Activating 1024.0 0 0 0 0 0.5552695394055701 P22515 0.9588389992713928 0.9387490153312684 0.0037887077778577813 1.0 1.2762000560760498 50.609904678992685 45.0 1.0 no 6759 chrXI_41346r 20551 essential YKL210W 2186 - TAGCACCTGCTACGACAAAA A|735|P A|735|T G|734|A G|734|D UBA1 UBiquitin Activating 1024.0 0 0 0 0 0.040298883099653814 P22515 0.9573720097541808 0.9523990154266356 0.9499930143356324 0.9446240067481996 0.009103248827159405 0.008056026883423328 1.0 0.002963090315461159 44.78072895337629 45.0 1.0 no 6760 chrXI_41420r 20553 essential YKL210W 2260 - GGACTTATACTCGTCCACGT K|759|N silent|AAG>AAA|K|759 UBA1 UBiquitin Activating 1024.0 0 0 0 0 0.5083201530188484 P22515 0.9355990290641784 0.39285424351692205 1.496999979019165 51.47970829263511 50.0 1.0 no 6761 chrXI_41419r 20554 essential YKL210W 2259 - GACTTATACTCGTCCACGTT K|759|N silent|AAG>AAA|K|759 UBA1 UBiquitin Activating 1024.0 0 0 0 0 0.896079517489009 P22515 0.9355990290641784 0.39285424351692205 1.496999979019165 49.3902110476895 45.0 1.0 no 6762 chrXI_57796r 20555 essential YKL203C 5541 + ACTTTATGGTTTACTTTTGG T|1848|S T|1848|I TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.711976888802492 P32600 0.8894810080528259 0.7940070033073425 0.032430499792099 0.002643322106450796 41.6503520634825 30.0 0.0 no 6763 chrXI_57825r 20556 essential YKL203C 5512 + GCTCTCTTCAAGATGCATTA S|1839|C S|1839|F S|1838|R silent|AGC>AGT|S|1838 TOR2 Target Of Rapamycin 2474.0 0 0 0 0 -0.31628255088660584 P32600 0.8412140011787415 0.8338299989700317 0.8579990267753601 0.04981409013271332 0.0028393205720931287 0.0853840634226799 47.41016591282124 40.0 0.0 no 6764 chrXI_57880r 20557 essential YKL203C 5457 + CACGTAATTCCAGCAATTAA H|1820|Q silent|CAC>CAT|H|1820 TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.8131220746739207 P32600 0.8001469969749451 0.01719186082482338 41.076614578792096 35.0 0.0 no 6765 chrXI_57881r 20558 essential YKL203C 5456 + GCACGTAATTCCAGCAATTA H|1820|Q silent|CAC>CAT|H|1820 H|1820|D H|1820|Y TOR2 Target Of Rapamycin 2474.0 0 0 0 0 -0.2999753772426644 P32600 0.8001469969749451 0.8400269746780396 0.9267280101776124 0.01719186082482338 0.013821495696902277 0.6826941967010498 45.849648988253925 40.0 0.0 no 6766 chrXI_57903r 20559 essential YKL203C 5434 + ACTCTTCTAATTTAATACAC S|1813|C S|1813|F Y|1812|* silent|TAC>TAT|Y|1812 TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.501293531850784 P32600 0.9104509949684144 0.8290489912033081 0.03994159027934074 0.0389803908765316 35.357802129937674 25.0 0.0 no 6767 chrXI_57978 20560 essential YKL203C 5362 - CTCATTAATATCAGTTACCG E|1794|Q E|1794|K TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.1625097797023697 P32600 0.9725610017776488 0.9505500197410583 41.165722164507606 35.0 0.0 no 6768 chrXI_58095r 20566 essential YKL203C 5242 + CTACACATTTTGACAACACA T|1749|R T|1749|I H|1750|D H|1750|Y TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.7006821066424975 P32600 0.7986829876899719 0.8890889883041382 0.9224330186843872 0.8651180267333984 0.0019903050269931555 0.0022081576753407717 0.2613638937473297 0.1611514687538147 39.969089248688825 35.0 0.0 no 6769 chrXI_58132r 20567 essential YKL203C 5205 + AGCAATCCAGATTCGATCCT S|1736|R silent|AGC>AGT|S|1736 P|1738|A P|1738|S TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.14237898905339305 P32600 0.9446129798889159 0.9244229793548584 0.9067559838294984 0.4588361978530884 0.5213624835014343 0.4130809009075165 50.27569666175464 45.0 0.0 no 6770 chrXI_58528 20576 essential YKL203C 4812 - CTCACTTGAGCATCCTCCTT silent|GTG>GTC|V|1610 silent|GTG>GTA|V|1610 V|1610|L V|1610|M TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.3600550763299513 P32600 0.9442070126533508 0.9636470079421996 0.19386444985866547 1.0 56.04068372424382 50.0 0.0 no 6771 chrXI_58587r 20577 essential YKL203C 4750 + GTCAAAAAAATATTGATGTG Q|1585|E Q|1585|* TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.4647122326130113 P32600 0.8904320001602173 0.09715474396944046 29.915411877716625 25.0 0.0 no 6772 chrXI_58612r 20578 essential YKL203C 4725 + ACTTGGAATACCAGATTACT T|1576|S T|1576|I TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.20714260497955225 P32600 0.8174830079078674 0.9177280068397522 0.025206739082932472 0.33275437355041504 42.1831964593859 35.0 0.0 no 6773 chrXI_58613r 20579 essential YKL203C 4724 + AACTTGGAATACCAGATTAC T|1576|S T|1576|I TOR2 Target Of Rapamycin 2474.0 0 0 0 0 -1.691503060636375 P32600 0.8174830079078674 0.9177280068397522 0.025206739082932472 0.33275437355041504 39.06700869263455 35.0 0.0 no 6774 chrXI_58648 20580 essential YKL203C 4692 - AGACGTTTATCTGAATTTTG R|1570|P R|1570|H TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.855517585150033 P32600 0.7869979739189148 0.8621749877929688 0.032518882304430015 0.03688579797744751 37.98424475266927 30.0 0.0 no 6775 chrXI_58697r 20582 essential YKL203C 4640 + AGCGCAGATTATAGCAGAGT A|1548|G A|1548|V Q|1549|E Q|1549|* TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.09042715160046376 P32600 0.8620539903640747 1.0030699968338013 0.8749740123748779 0.005423272494226694 1.0 0.008900368586182594 48.58961672211729 45.0 0.0 no 6776 chrXI_58833r 20585 essential YKL203C 4504 + ATGCAATTTTATGTTTGCAT A|1503|G A|1503|V TOR2 Target Of Rapamycin 2474.0 0 0 0 0 -0.8674229204234633 P32600 0.8699920177459717 0.87608402967453 0.01813392154872417 0.0056637958623468885 40.862487036808254 25.0 0.0 no 6777 chrXI_58884 20586 essential YKL203C 4456 - TTTCATGACGCTAGTATACT M|1491|I M|1491|I TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.12814282243680056 P32600 0.959855020046234 0.959855020046234 0.3100971281528473 0.3100971281528473 43.56375789470405 35.0 0.0 no 6778 chrXI_58957 20589 essential YKL203C 4383 - GCCATTGCCTTCTTCACTTC M|1467|I M|1467|I A|1468|P A|1468|T TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.19395921052162848 P32600 1.007140040397644 1.007140040397644 0.7857900261878967 0.8751829862594604 1.0 1.0 0.006364443339407444 0.005247093737125397 57.29950199820024 50.0 0.0 no 6779 chrXI_59016 20592 essential YKL203C 4324 - AAGCTCTTCCCACTCTCCAA E|1447|D silent|GAG>GAA|E|1447 E|1447|Q E|1447|K TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.3402710032292785 P32600 0.9504889845848083 1.0073699951171875 0.9831359982490541 0.4277474284172058 1.0 0.6521961092948914 55.84040959953245 50.0 0.0 no 6780 chrXI_59096r 20593 essential YKL203C 4241 + TCTTGCAGCATATAATGAGA L|1415|V L|1415|F A|1416|G A|1416|V TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.3931252752123852 P32600 0.8560119867324829 0.8372049927711487 0.9492369890213012 0.9748370051383972 0.012769452296197414 0.011083241552114487 0.368257611989975 0.2906179428100586 42.08176011154677 35.0 0.0 no 6781 chrXI_59156r 20595 essential YKL203C 4181 + ACACAATGAATTGCAGCTGA H|1395|Q silent|CAC>CAT|H|1395 H|1395|D H|1395|Y TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.5614961896410535 P32600 0.9576979875564576 0.8940989971160889 0.9475979804992676 0.18719345331192014 0.07621433585882187 0.9380333423614502 42.93272405905093 40.0 0.0 no 6782 chrXI_59249r 20596 essential YKL203C 4088 + GCCGAAAAATTCAACAATCG P|1364|R P|1364|L P|1364|A P|1364|S TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.3779739641265012 P32600 0.9266980290412904 0.9240260124206544 0.9806820154190063 0.9443619847297668 0.15454114973545074 0.0521121472120285 0.07538957893848419 0.14435693621635434 37.99815990982359 40.0 0.0 no 6783 chrXI_59335 20598 essential YKL203C 4005 - TACTTACCTAATGTATGGAT K|1341|N silent|AAG>AAA|K|1341 G|1340|A G|1340|D TOR2 Target Of Rapamycin 2474.0 0 0 0 0 -0.8877022476413223 P32600 0.955775022506714 0.8817160129547119 0.7757239937782288 0.35541754961013794 0.057887423783540726 0.0025363699533045288 40.30312155668662 30.0 0.0 no 6784 chrXI_59336 20599 essential YKL203C 4004 - ACTTACCTAATGTATGGATT K|1341|N silent|AAG>AAA|K|1341 G|1340|A G|1340|D TOR2 Target Of Rapamycin 2474.0 0 0 0 0 -0.2754999955514243 P32600 0.955775022506714 0.8817160129547119 0.7757239937782288 0.35541754961013794 0.057887423783540726 0.0025363699533045288 41.09404812345247 30.0 0.0 no 6785 chrXI_59341r 20601 essential YKL203C 3996 + CCTATCCCAATCCATACATT P|1333|R P|1333|L I|1334|M silent|ATC>ATT|I|1334 TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.3810061281933223 P32600 0.7903280258178711 0.8521940112113953 0.8556879758834839 0.0029026330448687077 0.003272836096584797 0.008749270811676979 49.98894559782707 40.0 0.0 no 6786 chrXI_59393r 20602 essential YKL203C 3944 + TCAAATGTTGTTAAATTTAG Q|1316|E Q|1316|* TOR2 Target Of Rapamycin 2474.0 0 0 0 0 1.249463910813231 P32600 0.8257619738578796 0.022499337792396545 30.947534057496572 20.0 0.0 no 6787 chrXI_59404 20603 essential YKL203C 3936 - AACAACATTTGATAAATCTC L|1318|F silent|TTG>TTA|L|1318 M|1317|I M|1317|I TOR2 Target Of Rapamycin 2474.0 0 0 0 0 -0.09162611552777547 P32600 0.8010290265083313 1.022439956665039 1.022439956665039 0.010130750946700571 0.7581806182861328 0.7581806182861328 32.46412236489124 25.0 0.0 no 6788 chrXI_59403 20604 essential YKL203C 3937 - TAACAACATTTGATAAATCT L|1318|F silent|TTG>TTA|L|1318 M|1317|I M|1317|I TOR2 Target Of Rapamycin 2474.0 0 0 0 0 1.4085447801647923 P32600 0.8010290265083313 1.022439956665039 1.022439956665039 0.010130750946700571 0.7581806182861328 0.7581806182861328 31.265833103985248 20.0 0.0 no 6789 chrXI_59418 20607 essential YKL203C 3922 - AATCTCGGGTGGGTTTTCAG E|1313|D silent|GAG>GAA|E|1313 E|1313|Q E|1313|K TOR2 Target Of Rapamycin 2474.0 0 0 0 0 -0.7738537346797744 P32600 0.9242449998855592 0.8664879798889159 0.7924299836158752 0.21351884305477145 0.08772982656955719 0.00915917567908764 50.71867200387004 50.0 0.0 no 6790 chrXI_59474r 20608 essential YKL203C 3863 + GCTTCAAACGTCATACCAAG L|1289|V L|1289|F Q|1290|E Q|1290|* TOR2 Target Of Rapamycin 2474.0 0 0 0 0 -0.1880953593965296 P32600 0.841949999332428 0.772441029548645 1.0083600282669067 0.006394407246261835 0.006265582516789436 0.10840161889791487 44.313417374862354 45.0 0.0 no 6791 chrXI_59459 20609 essential YKL203C 3881 - ATGCTTGAATCAAATCCTCT A|1300|P A|1300|T TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.2263592532473928 P32600 0.8476219773292542 0.9787560105323792 0.012715461663901806 0.0345853827893734 43.365310059649524 35.0 0.0 no 6792 chrXI_59501r 20610 essential YKL203C 3836 + TGCTTCATTCTCAAGTTGCT A|1280|G A|1280|V S|1281|* S|1281|L TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.22384773590453225 P32600 0.842956006526947 0.950694978237152 0.8687940239906311 0.035404890775680535 0.3111797273159027 0.004109739791601896 49.75467704720523 40.0 0.0 no 6793 chrXI_59502r 20611 essential YKL203C 3835 + ATGCTTCATTCTCAAGTTGC A|1280|G A|1280|V S|1281|* S|1281|L TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.4412789890564997 P32600 0.842956006526947 0.950694978237152 0.8687940239906311 0.035404890775680535 0.3111797273159027 0.004109739791601896 47.79278364407014 40.0 0.0 no 6794 chrXI_59540r 20612 essential YKL203C 3797 + AGTCAGCGTTTATTATCCGT silent|GTC>GTG|V|1267 silent|GTC>GTT|V|1267 S|1268|R silent|AGC>AGT|S|1268 TOR2 Target Of Rapamycin 2474.0 0 0 0 0 -0.2544738692663675 P32600 0.9206159710884094 0.4827329218387604 49.96111782047257 40.0 0.0 no 6795 chrXI_59600r 20613 essential YKL203C 3737 + GCTATCTATTCAGCTTCTAA L|1247|V silent|CTA>TTA|L|1247 S|1248|C S|1248|F TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.2825930167909002 P32600 0.8860509991645813 0.9229009747505188 0.8809009790420532 0.037820231169462204 0.006382667925208807 0.002507948782294989 45.52587907498452 35.0 0.0 no 6796 chrXI_59675 20617 essential YKL203C 3665 - ATGCATTCTTTAGGATATTT A|1228|P A|1228|T TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.986863392588396 P32600 0.8760319948196411 0.9487950205802916 0.008410166017711163 0.06273499876260757 40.669132421553066 25.0 0.0 no 6797 chrXI_59728 20618 essential YKL203C 3612 - TCTTCATAATTTTTCCTTTC D|1211|H D|1211|N E|1210|Q E|1210|K TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.7586062805085609 P32600 0.8697699904441833 0.9873409867286682 0.9843620061874391 0.9307690262794496 0.11591632664203645 0.4858931601047516 0.6246563792228699 0.8981814384460449 41.546752547984056 25.0 0.0 no 6798 chrXI_59816r 20620 essential YKL203C 3521 + GCATTCAGTGTACGATCAAC H|1175|D H|1175|Y S|1176|* S|1176|L TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.4798417228653375 P32600 0.8649129867553711 0.9069769978523254 0.9342849850654602 0.11493830382823945 0.04941395670175552 0.29476624727249146 45.408254096064645 45.0 0.0 no 6799 chrXI_59891 20623 essential YKL203C 3449 - AGTCGGTACCTAGTTGTAAA D|1156|H D|1156|N TOR2 Target Of Rapamycin 2474.0 0 0 0 0 -0.1160812026060777 P32600 0.860522985458374 0.9219840168952942 0.007084578741341829 0.024876467883586884 45.73680496799267 40.0 0.0 no 6800 chrXI_59913 20624 essential YKL203C 3427 - GAGCAAACTTAGCGTATTCA L|1148|F silent|TTG>TTA|L|1148 TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.9287314729880524 P32600 0.8527010083198547 0.05730322003364562 43.873344806876325 40.0 0.0 no 6801 chrXI_59993 20626 essential YKL203C 3347 - TTCTTGATGACATTTCAGAG R|1122|T R|1122|K TOR2 Target Of Rapamycin 2474.0 0 0 0 0 1.1957680660432302 P32600 0.8622369766235352 0.9361500144004822 0.009561360813677313 0.12381458282470705 40.68553438944616 35.0 0.0 no 6802 chrXI_60082 20627 essential YKL203C 3258 - TCAGTCATTCTAACAACGAT E|1093|Q E|1093|K M|1091|I M|1091|I TOR2 Target Of Rapamycin 2474.0 0 0 0 0 -0.03822336018680661 P32600 0.9022200107574464 0.895779013633728 1.0089499950408936 1.0089499950408936 0.018509307876229286 0.014324433170259 0.2135622352361679 0.2135622352361679 40.60654551547373 35.0 0.0 no 6803 chrXI_60095 20628 essential YKL203C 3245 - CAACGATAGGCATAATCAAA V|1088|L V|1088|I TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.9153126294336444 P32600 1.0944399833679201 1.0991899967193604 0.26911020278930664 1.0 36.9344400066804 35.0 0.0 no 6804 chrXI_60194 20630 essential YKL203C 3146 - GGTCGTTCTCAAGAATATCA D|1055|H D|1055|N TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.5352645853029592 P32600 0.8008149862289429 0.8877059817314148 0.002495589666068554 0.007231537252664566 44.19908546374114 40.0 0.0 no 6805 chrXI_60256r 20631 essential YKL203C 3081 + TCGATATCTAAGGCTCTGGA S|1028|W S|1028|L TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.7990368637014993 P32600 0.8069220185279846 0.9325829744338988 0.0037175153847783813 0.04663170129060745 47.17192002984524 45.0 0.0 no 6806 chrXI_60266r 20632 essential YKL203C 3071 + TGTCATAGAATCGATATCTA silent|GTC>GTG|V|1025 silent|GTC>GTT|V|1025 TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.2297816586629532 P32600 38.30957823481378 30.0 0.0 no 6807 chrXI_60397r 20634 essential YKL203C 2940 + GACTTTTATTTTCAGCAACT D|981|E silent|GAC>GAT|D|981 TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.32665587669224005 P32600 1.0183099508285522 1.0 41.70291423494109 30.0 0.0 no 6808 chrXI_60499r 20637 essential YKL203C 2838 + ATGCATATTTTTCAAAACCT H|948|D H|948|Y TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.9723349023204896 P32600 0.9774399995803832 1.015030026435852 0.16360236704349518 1.0 38.88708374799386 25.0 0.0 no 6809 chrXI_60634r 20638 essential YKL203C 2703 + GACATCGCATTGCTAATGCA D|902|E silent|GAC>GAT|D|902 I|903|M silent|ATC>ATT|I|903 TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.08363004208125815 P32600 0.9304839968681335 1.0560699701309204 0.05572763457894325 0.269449383020401 47.82554502530946 45.0 0.0 no 6810 chrXI_60760 20640 essential YKL203C 2580 - ACAGTTCCACGCCTGATATG V|867|L V|867|I G|865|A G|865|E TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.13884292079996674 P32600 1.0890599489212036 1.0937999486923218 1.0017499923706057 1.014580011367798 0.15901324152946472 1.0 0.009455928578972816 1.0 51.37183580291526 50.0 0.0 no 6811 chrXI_60823 20643 essential YKL203C 2517 - AACTCTGGGTAGTCTAGTAA E|845|D silent|GAG>GAA|E|845 E|845|Q E|845|K TOR2 Target Of Rapamycin 2474.0 0 0 0 0 -0.4876730875014372 P32600 1.0470199584960938 1.0925999879837036 1.0465500354766846 0.5834740400314331 0.776549220085144 0.7730503678321838 44.90329051035711 40.0 0.0 no 6812 chrXI_60808 20644 essential YKL203C 2532 - ATCAAAATGCCAAGTAACTC L|850|F silent|TTG>TTA|L|850 TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.7255354084764329 P32600 0.8832529783248901 0.04200790822505951 38.48371958944068 35.0 0.0 no 6813 chrXI_60824 20646 essential YKL203C 2516 - ACTCTGGGTAGTCTAGTAAA E|845|Q E|845|K E|845|D silent|GAG>GAA|E|845 TOR2 Target Of Rapamycin 2474.0 0 0 0 0 -0.12002113136165465 P32600 1.0925999879837036 1.0465500354766846 1.0470199584960938 0.776549220085144 0.7730503678321838 0.5834740400314331 44.90329051035711 40.0 0.0 no 6814 chrXI_60847r 20647 essential YKL203C 2490 + GCTTCCTCTGGTTATGTTGT A|831|G A|831|V S|832|C S|832|F TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.6839880387854569 P32600 0.9964659810066224 0.950694978237152 0.805662989616394 0.7909290194511414 0.2311968058347702 0.05306946113705635 0.011409366503357887 0.013778193853795528 55.3838280151262 45.0 0.0 no 6815 chrXI_61006r 20648 essential YKL203C 2331 + TCCACCGCTTTAAAGGTTTT silent|TCC>TCG|S|778 silent|TCC>TCT|S|778 S|778|C S|778|F TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.1947179603642842 P32600 0.8415539860725403 0.7929919958114624 0.019074592739343643 0.01642601005733013 48.81478025848134 40.0 0.0 no 6816 chrXI_61031 20649 essential YKL203C 2309 - CTACGGCAGATGAAGCATCC V|776|L V|776|I A|775|P A|775|T TOR2 Target Of Rapamycin 2474.0 0 0 0 0 -0.09562363235768616 P32600 0.9148759841918944 0.918857991695404 0.9589080214500428 0.9852089881896972 0.0 0.0 0.11873365193605424 0.4489191174507141 50.083286256437184 55.00000000000001 0.0 no 6817 chrXI_61049r 20650 essential YKL203C 2288 + CGTCATTCTTCCTAAATGCC silent|GTC>GTG|V|764 silent|GTC>GTT|V|764 TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.44017291926395097 P32600 48.941725319915236 45.0 0.0 no 6818 chrXI_61072 20651 essential YKL203C 2268 - TCTAGAATAGGATCAATATA D|763|H D|763|N TOR2 Target Of Rapamycin 2474.0 0 0 0 0 -0.0022235686986969982 P32600 1.0565799474716189 1.0917899608612058 0.11311256140470505 0.3560190796852112 34.011072906010554 25.0 0.0 no 6819 chrXI_61151r 20652 essential YKL203C 2186 + CTCAAATATGCCAAAAAAAA S|730|* S|730|L TOR2 Target Of Rapamycin 2474.0 0 0 0 0 1.2985464954832275 P32600 0.8435350060462952 0.06669534742832184 31.0641295105828 25.0 0.0 no 6820 chrXI_61381 20655 essential YKL203C 1959 - TCCAATCTAATTTCTGCAAC L|659|F silent|TTG>TTA|L|659 E|660|Q E|660|K TOR2 Target Of Rapamycin 2474.0 0 0 0 0 1.1347017350043025 P32600 0.9585739970207214 0.9850919842720032 0.9716770052909852 0.7015263438224792 0.5886407494544983 0.8346375823020935 41.86621671085561 35.0 0.0 no 6821 chrXI_61448r 20657 essential YKL203C 1889 + ATCAGTTCATGCTTTACACT S|631|* S|631|L TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.6805058473181609 P32600 0.7940700054168701 0.002669766079634428 46.22409984016286 35.0 0.0 no 6822 chrXI_61575r 20658 essential YKL203C 1762 + ATTCCTTGACGGAGTTTGTT S|589|C S|589|F silent|TCC>TCG|S|589 silent|TCC>TCT|S|589 TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.8733616960353291 P32600 0.9104509949684144 0.8253030180931091 0.10117467492818832 0.08420234173536299 48.85702988456444 40.0 0.0 no 6823 chrXI_61572 20659 essential YKL203C 1768 - AAGCCTAACAAACTCCGTCA R|595|S silent|AGG>AGA|R|595 R|595|T R|595|K TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.5476249622216365 P32600 0.8846099972724915 0.90522700548172 0.9872689843177797 0.11471451073884965 0.06746157258749008 0.15376339852809906 46.641606430919296 45.0 0.0 no 6824 chrXI_61774r 20660 essential YKL203C 1563 + TTACTGTCGATATCCTTATC L|523|V silent|CTG>TTG|L|523 TOR2 Target Of Rapamycin 2474.0 0 0 0 0 -0.012509504428385318 P32600 1.0478899478912354 0.15725351870059967 43.90049545314389 35.0 0.0 no 6825 chrXI_61853 20661 essential YKL203C 1487 - TCATTAAAGTCTCCTGCATA M|502|I M|502|I TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.7438149721088292 P32600 1.022439956665039 1.022439956665039 0.49175149202346796 0.49175149202346796 44.6208301129484 35.0 0.0 no 6826 chrXI_61826r 20664 essential YKL203C 1511 + TAACGAGAAAATACCCTCTT N|505|K silent|AAC>AAT|N|505 TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.3846950776783981 P32600 0.9732850193977356 0.1895743012428284 39.85490477735994 35.0 0.0 no 6827 chrXI_62028r 20666 essential YKL203C 1309 + CACTTATTCTGGATAATATT L|438|V L|438|F TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.6339244971509614 P32600 0.9798560142517091 0.9911710023880004 0.2839518189430237 0.050511855632066734 36.82759980901477 25.0 0.0 no 6828 chrXI_62038 20667 essential YKL203C 1302 - TCCAGAATAAGTGTCATATA silent|CTG>CTC|L|440 silent|CTG>CTA|L|440 D|441|H D|441|N TOR2 Target Of Rapamycin 2474.0 0 0 0 0 -0.08631048552435586 P32600 0.9431809782981871 0.983748972415924 0.11880078166723253 0.4902596771717072 39.27267187887918 30.0 0.0 no 6829 chrXI_62095r 20669 essential YKL203C 1242 + CCTTTTATATTAGTTTCTAT P|415|R P|415|L TOR2 Target Of Rapamycin 2474.0 0 0 0 0 -0.08179227205583423 P32600 0.9629480242729188 0.9432920217514038 0.5086786746978761 0.29255411028862 39.33398463840814 20.0 0.0 no 6830 chrXI_62314 20671 essential YKL203C 1026 - TCATATTTATCCCTGAGATA D|349|H D|349|N TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.10433558240751996 P32600 0.9450010061264038 0.9851130247116088 0.15185385942459104 0.4763201475143433 43.325358280560245 30.0 0.0 no 6831 chrXI_62325r 20672 essential YKL203C 1012 + GCTTGAAAGCACCTTATCTC S|338|R silent|AGC>AGT|S|338 TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.3389227717146671 P32600 0.99938702583313 0.6008940935134888 47.75434420751021 45.0 0.0 no 6832 chrXI_62366r 20673 essential YKL203C 971 + TTCAGTGCATGCTACTCTGT S|325|* S|325|L TOR2 Target Of Rapamycin 2474.0 0 0 0 0 -0.3468078806751743 P32600 0.933571994304657 0.6334587335586548 52.543711181814565 45.0 0.0 no 6833 chrXI_62487 20675 essential YKL203C 853 - ACATTTACCCAATGCCACTG C|291|S C|291|Y TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.5499189145569829 P32600 0.8717120289802551 0.8467530012130737 0.07214324921369553 0.0067643881775438786 49.52749090047632 45.0 0.0 no 6834 chrXI_62538r 20676 essential YKL203C 799 + ACAATATTTGGGTGCCATTA D|267|E silent|GAC>GAT|D|267 TOR2 Target Of Rapamycin 2474.0 0 0 0 0 -0.08145104575255048 P32600 1.0696699619293213 0.5932050943374634 45.23020075460687 35.0 0.0 no 6835 chrXI_62549r 20677 essential YKL203C 788 + CTCTATCTTAGACAATATTT S|264|C S|264|F I|265|M silent|ATC>ATT|I|265 TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.8518982997337198 P32600 0.8890249729156494 1.0214799642562866 0.925453007221222 0.0520661398768425 0.06351824104785919 0.01320171356201172 37.059408333026745 25.0 0.0 no 6836 chrXI_62550r 20678 essential YKL203C 787 + ACTCTATCTTAGACAATATT S|264|C S|264|F N|263|K silent|AAC>AAT|N|263 TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.6174955654950721 P32600 0.8890249729156494 1.0214799642562866 0.9364579916000366 0.0520661398768425 0.06351824104785919 0.9242520332336426 37.24771659641653 25.0 0.0 no 6837 chrXI_62787 20686 essential YKL203C 553 - TCTCATAACTTCAATGTCAC M|190|I M|190|I R|191|T R|191|K TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.8453493373064083 P32600 0.9156699776649476 0.9156699776649476 0.9314119815826416 0.9633830189704896 0.059278294444084174 0.059278294444084174 0.5854434370994568 0.9991551041603088 40.69941442819908 35.0 0.0 no 6838 chrXI_62836 20687 essential YKL203C 504 - GCCAGTCTTGAAGTTTGGTT silent|CTG>CTC|L|174 silent|CTG>CTA|L|174 A|175|P A|175|T TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.02709742703733714 P32600 0.8016020059585571 0.9061689972877502 0.1848573237657547 0.3783913552761078 52.16325303632443 45.0 0.0 no 6839 chrXI_62837r 20688 essential YKL203C 500 + GCCAAACCAAACTTCAAGAC P|168|R P|168|L P|168|A P|168|S TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.7434515534919883 P32600 0.8964200019836426 0.933135986328125 0.976522982120514 0.9638890027999878 0.464314877986908 0.26840493083000183 1.0 0.8375778198242188 42.80155652621778 45.0 0.0 no 6840 chrXI_62864r 20689 essential YKL203C 473 + CTCATTCTACCTGAGTACAG S|159|* S|159|L F|160|L silent|TTC>TTT|F|160 TOR2 Target Of Rapamycin 2474.0 0 0 0 0 -0.02140501581830656 P32600 0.9095860123634338 1.070680022239685 0.03581792116165161 0.4436378180980681 47.14485900547288 45.0 0.0 no 6841 chrXI_62982r 20692 essential YKL203C 355 + TATCTGCTGAGCAATTTCAA S|120|C S|120|F A|121|G A|121|V TOR2 Target Of Rapamycin 2474.0 0 0 0 0 -0.2691437617348176 P32600 0.7784709930419922 0.7596049904823303 0.9987959861755372 0.980668008327484 0.013560419902205469 0.011769850738346577 0.7062335014343262 0.3765268325805664 42.93679188457026 35.0 0.0 no 6842 chrXI_63120 20695 essential YKL203C 220 - ATCTAGTTCTGAATCTACAA D|80|H D|80|N TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.4418441296456568 P32600 0.9000099897384644 1.0548399686813354 0.1314295530319214 0.581710696220398 39.10562689995471 30.0 0.0 no 6843 chrXI_63151r 20696 essential YKL203C 186 + ACTGGTTCTGCTGGTCATAT T|63|S T|63|I TOR2 Target Of Rapamycin 2474.0 0 0 0 0 0.08382772233584287 P32600 1.000890016555786 0.9835339784622192 52.19946936771226 45.0 0.0 no 6844 chrXI_75166 20702 essential YKL196C 349 - CTTCATTTTCAATGCATCAT M|122|I M|122|I YKT6 200.0 0 1 0 0 1.1800235987809684 P36015 0.10487432032823564 0.10487432032823564 3.6911199092864986 3.6911199092864986 4.0328335762023935 4.0328335762023935 42.3636172094362 30.0 0.0 no 6845 chrXI_75197 20703 essential YKL196C 318 - ACATCTGCCCACTCTTCCTT V|113|L V|113|M D|112|H D|112|N YKT6 200.0 0 0 0 0 0.620434686262712 P36015 0.4671720266342163 0.1926846206188202 0.13964799046516418 0.8397377729415894 0.10531800240278244 0.3081820011138916 -0.468531996011734 0.1103679984807968 -0.15129519999027252 -0.11362019926309586 58.85249098619153 50.0 0.0 no 6846 chrXI_75240r 20706 essential YKL196C 272 + CACACTATTAAACAAAATAT T|92|R T|92|I L|93|V silent|CTA>TTA|L|93 YKT6 200.0 0 0 0 0 -0.472466390097752 P36015 0.015506128780543802 0.02071806415915489 0.14798356592655182 -0.5988280177116394 -0.9455599784851074 1.7354600429534912 29.41785937493967 20.0 0.0 no 6847 chrXI_75271 20707 essential YKL196C 244 - TCTGACAGGATATTCTTTGT R|88|T R|88|K V|87|L V|87|I YKT6 200.0 0 0 0 0 -0.4923555951281037 P36015 0.12749288976192474 0.3216210603713989 0.5179581642150879 0.3084254562854767 0.6596540212631226 -0.07305199652910233 -0.9986839890480042 -0.6269140243530273 -0.9165480136871338 -0.4772717952728272 44.17684608855342 35.0 0.0 no 6848 chrXI_75304 20708 essential YKL196C 211 - ACCACATATGCCCTCACTCC G|77|R G|77|S G|77|A G|77|D YKT6 200.0 0 0 0 0 0.15660712852081524 P36015 0.008399897255003452 0.13200676441192627 0.5855465531349182 0.009069723077118395 10.096542358398438 0.15118800103664398 -1.6007479429244995 1.7031680345535278 58.09232018123043 55.00000000000001 0.0 no 6849 chrXI_75315r 20711 essential YKL196C 197 + CCACGTTTATGCCAGGAGTG H|67|Q silent|CAC>CAT|H|67 H|67|D H|67|Y YKT6 200.0 0 0 0 0 -0.008856332437221255 P36015 0.004175571724772453 0.008651962503790855 0.003965807147324085 2.0337820053100586 1.3239359855651855 -0.9984700083732604 53.39336572982705 55.00000000000001 0.0 no 6850 chrXI_75402 20713 essential YKL196C 113 - CAGCAAAAAAAGTCATAAAC A|44|P A|44|T YKT6 200.0 0 0 0 0 0.046239033805769575 P36015 0.02404583804309368 0.20424634218215945 6.702335834503174 4.814023971557617 30.382602953291553 30.0 0.0 no 6851 chrXI_75425r 20714 essential YKL196C 87 + TTCTTTGAAAGGTCTAGTGT F|30|L silent|TTC>TTT|F|30 YKT6 200.0 0 0 0 0 -0.2917496933163948 P36015 0.13828693330287933 0.07062999904155731 -0.6159685850143433 43.20587468375084 35.0 0.0 no 6852 chrXI_75895 20722 essential YKL195W 74 + ACACCAAACAAGACGTCTCA H|26|Q silent|CAC>CAT|H|26 H|26|D H|26|Y MIA40 Mitochondrial intermembrane space Import and Assembly 403.0 0 0 0 0 -0.14946624872214942 P36046 0.9588389992713928 0.9473130106925964 0.9489949941635132 44.373473295891415 45.0 1.0 no 6853 chrXI_75898r 20723 essential YKL195W 80 - ACGCCATGAGACGTCTTGTT A|33|P A|33|T silent|GCG>GCC|A|33 silent|GCG>GCA|A|33 MIA40 Mitochondrial intermembrane space Import and Assembly 403.0 0 0 0 0 0.5809681718611371 P36046 0.9573720097541808 0.9523990154266356 52.0192475348382 50.0 1.0 no 6854 chrXI_75944 20726 essential YKL195W 123 + TCCAATCAGGAAAAAACAGC silent|TCC>TCG|S|42 silent|TCC>TCT|S|42 S|42|C S|42|F MIA40 Mitochondrial intermembrane space Import and Assembly 403.0 0 0 0 0 0.12108272508346445 P36046 0.945252001285553 0.9294660091400146 38.428981857284384 40.0 1.0 no 6855 chrXI_76027 20729 essential YKL195W 206 + GCCTCTTTTCGCCTCAAGGA P|70|R P|70|L P|70|A P|70|S MIA40 Mitochondrial intermembrane space Import and Assembly 403.0 0 0 0 0 0.34406947882560074 P36046 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 57.97281813230149 55.00000000000001 1.0 no 6856 chrXI_76038r 20730 essential YKL195W 220 - ATCGGATTCTACCTTCCTTG D|80|H D|80|N MIA40 Mitochondrial intermembrane space Import and Assembly 403.0 0 1 0 0 0.17375827458885829 P36046 0.9486550092697144 0.956179976463318 0.06347084790468216 0.1679227501153946 0.52920001745224 -0.4269999861717224 50.766027384715976 45.0 1.0 no 6857 chrXI_76065r 20731 essential YKL195W 247 - ACTGGAAAGCTCTTCCTCTG S|89|T S|89|N MIA40 Mitochondrial intermembrane space Import and Assembly 403.0 0 0 0 0 -0.2768682396746856 P36046 0.9512869715690612 0.9536849856376648 0.5398730635643005 0.07229392230510713 50.15975769151015 50.0 1.0 no 6858 chrXI_76056r 20732 essential YKL195W 238 - CTCTTCCTCTGCGGTTTTAT E|86|Q E|86|K E|85|Q E|85|K MIA40 Mitochondrial intermembrane space Import and Assembly 403.0 0 1 0 0 0.15390551278746556 P36046 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.08501235395669937 0.09633926302194597 53.963083706461866 45.0 1.0 no 6859 chrXI_76214 20735 essential YKL195W 393 + GCTTCAAAAGTAGCTGAAGA A|132|G A|132|V S|133|* S|133|L MIA40 Mitochondrial intermembrane space Import and Assembly 403.0 0 0 0 0 -1.2273358585208527 P36046 0.9484469890594482 0.9504740238189696 0.9298099875450134 0.8198000192642212 41.265234113820384 40.0 1.0 no 6860 chrXI_76275r 20736 essential YKL195W 457 - TTCATCAGTATCTTTATCTT E|159|Q E|159|K D|158|H D|158|N MIA40 Mitochondrial intermembrane space Import and Assembly 403.0 0 1 0 0 0.4627616993532183 P36046 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.4833118617534638 0.6840100288391113 0.2500934898853302 0.5367524623870851 41.63320060738232 25.0 1.0 no 6861 chrXI_76347r 20737 essential YKL195W 529 - TTCATCCTTTTGATTGTTAG E|183|Q E|183|K D|182|H D|182|N MIA40 Mitochondrial intermembrane space Import and Assembly 403.0 0 0 0 0 0.3950754433255871 P36046 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.34293803572654724 0.4129243493080139 0.11665068566799165 0.3074004054069519 42.86605095413489 30.0 1.0 no 6862 chrXI_76175 20740 essential YKL195W 354 + ACTGAAGCTGGCCCTCAATT T|119|S T|119|I MIA40 Mitochondrial intermembrane space Import and Assembly 403.0 0 1 0 0 0.7663866645922786 P36046 0.9491789937019348 0.9472420215606691 52.94229286982779 50.0 1.0 no 6863 chrXI_79126r 20741 essential YKL193C 734 + AAACCTAAAACTAACTACTT N|246|K silent|AAC>AAT|N|246 L|247|V silent|CTA>TTA|L|247 SDS22 homolog of S. pombe SDS22 338.0 0 0 0 0 0.14264570351091194 P36047 0.9439849853515624 0.9512209892272948 0.05467081442475319 0.3147805333137512 0.41679999232292175 33.26044264128478 25.0 0.0 no 6864 chrXI_79633 20748 essential YKL193C 230 - CTTCGCTTATGCTTTCGATC E|83|Q E|83|K S|82|T S|82|N SDS22 homolog of S. pombe SDS22 338.0 0 1 0 0 -0.9916923016265601 P36047 0.956179976463318 0.9475290179252625 0.9512869715690612 0.9536849856376648 0.4401236474514008 0.5233128070831299 0.3461833894252777 0.32626038789749146 -1.7696000337600708 1.0140000581741333 49.09113439986567 45.0 0.0 no 6865 chrXI_79740 20749 essential YKL193C 123 - TCAATAACCTCTACATCATC D|48|H D|48|N SDS22 homolog of S. pombe SDS22 338.0 0 0 0 0 -0.004370231734497354 P36047 0.9486550092697144 0.956179976463318 0.10178688913583757 0.13588914275169373 41.34441236338336 35.0 0.0 no 6866 chrXI_79822r 20750 essential YKL193C 38 + AGACGAAAGACACAAGATTG D|14|E silent|GAC>GAT|D|14 SDS22 homolog of S. pombe SDS22 338.0 0 0 0 0 0.021618343369404103 P36047 0.9532920122146606 1.0 36.01929167291701 40.0 0.0 no 6867 chrXI_80271 20751 essential YKL192C 247 - GAGCAGCTCGACAGTGTCCA silent|CTG>CTC|L|88 silent|CTG>CTA|L|88 E|87|D silent|GAG>GAA|E|87 ACP1 Acyl Carrier Protein 125.0 0 0 0 0 0.028377706496639288 P32463 0.9362990260124208 0.0 57.99033000904353 60.0 0.0 no 6868 chrXI_80309r 20752 essential YKL192C 206 + CAGCGATACCCAATTTCACA S|70|R silent|AGC>AGT|S|70 ACP1 Acyl Carrier Protein 125.0 0 1 0 0 0.12604501450393552 P32463 0.9233329892158508 0.438934326171875 48.30814487239184 45.0 0.0 no 6869 chrXI_80436 20754 essential YKL192C 82 - TCTTTGTGCGAGTATGGTGT R|34|T R|34|K ACP1 Acyl Carrier Protein 125.0 0 0 0 0 -1.9360198286759709 P32463 0.9150789976119996 0.9426450133323668 0.035676512867212296 0.09123816341161728 51.07960210799962 45.0 0.0 no 6870 chrXI_80474r 20756 essential YKL192C 41 + TTCTGCGTACCGCACTATAA S|15|C S|15|F A|16|G A|16|V ACP1 Acyl Carrier Protein 125.0 0 0 0 0 0.44102835095496296 P32463 0.9268739819526672 0.9125909805297852 0.9304500222206116 0.9312549829483032 0.0983954668045044 0.05227334424853325 0.13541065156459808 0.20455725491046906 48.95908184574972 45.0 0.0 no 6871 chrXI_84729 20760 essential YKL189W 25 + ACTTGGACATGGCATTTTGG D|9|E silent|GAC>GAT|D|9 HYM1 399.0 0 0 0 0 -1.36911434353565 P32464 47.64264087134047 45.0 1.0 no 6872 chrXI_84765 20762 essential YKL189W 61 + AGACCCCTTCCGATTATGCC T|22|S T|22|I silent|ACC>ACG|T|22 silent|ACC>ACT|T|22 HYM1 399.0 0 0 0 0 0.7604859881662538 P32464 0.5340431928634644 0.1159517467021942 57.936874653178684 55.00000000000001 1.0 no 6873 chrXI_84770r 20765 essential YKL189W 69 - ATCAACCTGGCATAATCGGA L|29|F silent|TTG>TTA|L|29 R|28|S silent|AGG>AGA|R|28 HYM1 399.0 0 0 0 0 -0.09507417717749758 P32464 0.6967605948448181 0.014993284828960897 1.3372000455856323 47.00754142803106 45.0 1.0 no 6874 chrXI_84769r 20766 essential YKL189W 68 - TCAACCTGGCATAATCGGAA L|29|F silent|TTG>TTA|L|29 R|28|S silent|AGG>AGA|R|28 HYM1 399.0 0 0 0 0 -0.4248944650580239 P32464 0.6967605948448181 0.014993284828960897 1.3372000455856323 45.57954533799199 45.0 1.0 no 6875 chrXI_84814 20767 essential YKL189W 110 + CAGCTCACCCTCGCTGACTC S|38|R silent|AGC>AGT|S|38 S|39|* S|39|L HYM1 399.0 0 0 0 0 -0.6837276723049351 P32464 0.22979684174060824 0.4241454005241394 -0.24959999322891235 60.442074035820504 65.0 1.0 no 6876 chrXI_84907 20768 essential YKL189W 203 + TACGGATCCTCACCCAACTC T|69|R T|69|M HYM1 399.0 0 0 0 0 -0.35410793763675386 P32464 0.5184929370880127 0.10502441972494124 -0.25099998712539673 0.09799999743700027 53.483135078420325 55.00000000000001 1.0 no 6877 chrXI_84954r 20772 essential YKL189W 253 - GAACACGTCGGCACGATGCA silent|GTG>GTC|V|90 silent|GTG>GTA|V|90 V|90|L V|90|M HYM1 399.0 0 0 0 0 0.3074045238063037 P32464 1.0 0.027889043092727658 51.49062899064632 60.0 1.0 no 6878 chrXI_84966r 20773 essential YKL189W 265 - TAGCAGTTCATAGAACACGT silent|CTG>CTC|L|94 silent|CTG>CTA|L|94 HYM1 399.0 0 0 0 0 -0.5471535171483335 P32464 43.98820443508356 40.0 1.0 no 6879 chrXI_85209 20775 essential YKL189W 505 + TCAAATACGAACAACTTTGT I|169|M silent|ATC>ATT|I|169 HYM1 399.0 0 0 0 0 0.4615791472417349 P32464 0.09057264775037767 35.7934159935914 30.0 1.0 no 6880 chrXI_85247r 20778 essential YKL189W 546 - TCAAAGAATTTCCATAGTTG E|189|Q E|189|K HYM1 399.0 0 0 0 0 0.4139979971354546 P32464 0.17532528936862946 0.4765454530715942 37.37656399902141 30.0 1.0 no 6881 chrXI_85262 20779 essential YKL189W 558 + TTCTTTGAGTTTGCGAAACT F|187|L silent|TTC>TTT|F|187 HYM1 399.0 0 0 0 0 -0.3352591695402544 P32464 0.027971595525741574 42.47457111441389 35.0 1.0 no 6882 chrXI_85339 20780 essential YKL189W 635 + ACATCCTAAATTAGTGTCTA H|213|D H|213|Y P|214|A P|214|S HYM1 399.0 0 0 0 0 -1.1323596193437635 P32464 0.04036293551325798 0.005229486152529717 0.7182687520980835 0.7216899991035461 -2.481600046157837 5.414000034332275 41.02407673152044 30.0 1.0 no 6883 chrXI_92862r 20782 essential YKL186C 414 + CCTCTATGGGGTCCATATTT L|140|V silent|CTA>TTA|L|140 P|139|R P|139|L MTR2 Mrna TRansport 184.0 0 0 0 0 0.16375396234550105 P34232 0.937067985534668 0.9259650111198424 0.9257439970970154 0.2314589321613312 0.05308214575052261 0.033187072724103935 0.8293799757957458 53.13943348202043 45.0 0.0 no 6884 chrXI_92885 20785 essential YKL186C 394 - TCTTGGCTTGTTCATATCGT R|138|T R|138|K K|136|N silent|AAG>AAA|K|136 MTR2 Mrna TRansport 184.0 0 0 0 0 0.5250464994460796 P34232 0.9407349824905396 0.9577590227127076 0.9387279748916626 0.0 0.0 49.994604560748776 40.0 0.0 no 6885 chrXI_92913 20786 essential YKL186C 366 - TTTCTGTTCCCAGTGTTATT R|128|T R|128|K MTR2 Mrna TRansport 184.0 0 1 0 0 -0.4400675028573209 P34232 0.9340770244598388 0.9576690196990968 0.5588929057121277 1.0 50.87150493947274 35.0 0.0 no 6886 chrXI_92921r 20788 essential YKL186C 355 + CCATTCAACCAAATAACACT silent|CCC>CCG|P|119 silent|CCC>CCT|P|119 Q|121|E Q|121|* MTR2 Mrna TRansport 184.0 0 0 0 1 -0.8918834600623438 P34232 0.9469069838523864 1.0 0.4663600027561188 40.48147823005826 35.0 0.0 no 6887 chrXI_92922r 20789 essential YKL186C 354 + CCCATTCAACCAAATAACAC silent|CCC>CCG|P|119 silent|CCC>CCT|P|119 P|119|R P|119|L MTR2 Mrna TRansport 184.0 0 0 0 1 -1.253609097048877 P34232 0.9457629919052124 0.9455419778823853 0.2106873244047165 1.0 42.29630894720253 40.0 0.0 no 6888 chrXI_93005 20790 essential YKL186C 274 - GACGTTGCATATCAACGTGC V|98|L V|98|I MTR2 Mrna TRansport 184.0 0 0 0 0 -0.3341532156624321 P34232 0.9369810223579408 0.944877028465271 0.6875661611557007 0.8541678190231323 -1.176120042800903 -0.5548800230026245 47.77217038921328 50.0 0.0 no 6889 chrXI_100699r 20797 essential YKL182W 31 - CTCTAAAGAACCGTGAGATA E|17|Q E|17|K FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -0.3472864185503079 P07149 0.09099256247282027 0.15720053017139435 40.29378275425614 40.0 1.0 no 6890 chrXI_100700r 20798 essential YKL182W 32 - GCTCTAAAGAACCGTGAGAT E|17|Q E|17|K E|17|D silent|GAG>GAA|E|17 FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -1.0011948384184222 P07149 0.09099256247282027 0.15720053017139435 0.11600452661514282 44.190441225115926 45.0 1.0 no 6891 chrXI_100800r 20802 essential YKL182W 132 - TCTGCAGCAAACCCTTCAGT D|51|H D|51|N A|50|P A|50|T FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -1.9493835345064512 P07149 0.1096710041165352 0.4625577628612518 0.2755540311336517 0.5591017603874207 53.9990793917828 50.0 1.0 no 6892 chrXI_100833 20804 essential YKL182W 162 + ACCACACCTGCTGAACTAGT silent|ACC>ACG|T|55 silent|ACC>ACT|T|55 T|55|S T|55|I FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 0.2845684324261123 P07149 0.7428757548332214 0.1890492141246796 51.94761237889321 50.0 1.0 no 6893 chrXI_100834 20805 essential YKL182W 163 + CCACACCTGCTGAACTAGTG T|56|R T|56|I silent|ACC>ACG|T|55 silent|ACC>ACT|T|55 FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 0.022988457167744225 P07149 0.051901549100875854 0.02617719769477844 51.44849140968718 55.00000000000001 1.0 no 6894 chrXI_100877 20806 essential YKL182W 206 + TTCTCTAGTCGAACCTTCCA S|70|C S|70|F L|71|V silent|CTA>TTA|L|71 FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 0.7277373490446314 P07149 0.05425221100449562 0.05639061331748961 0.2514132559299469 51.594372090107136 45.0 1.0 no 6895 chrXI_100925r 20807 essential YKL182W 257 - TTTCAAATTCTGTTAAGCAA E|92|Q E|92|K FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 0.7738851149078843 P07149 0.5448554158210754 0.8114690780639648 36.50741694640431 25.0 1.0 no 6896 chrXI_101053r 20809 essential YKL182W 385 - TCTCTTAGCCATTATTCTGG K|134|N silent|AAG>AAA|K|134 R|135|T R|135|K FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -0.8852104380438995 P07149 0.5441718101501465 0.5221967101097107 0.9417428970336914 48.82051544629701 40.0 1.0 no 6897 chrXI_101089 20810 essential YKL182W 418 + AATCCAACTCTGCTCTTTTT S|141|C S|141|F silent|TCC>TCG|S|141 silent|TCC>TCT|S|141 FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 0.4975823925115493 P07149 0.17680560052394867 0.7002260684967041 46.71236358797182 35.0 1.0 no 6898 chrXI_100712 20811 essential YKL182W 41 + TTCTTTAGAGCACGTGCTTC S|15|C S|15|F FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 0.2252832538874441 P07149 0.05109202116727829 0.049429550766944885 49.785314013753464 45.0 1.0 no 6899 chrXI_101097 20812 essential YKL182W 426 + TCTGCTCTTTTTAGGGCCGT S|143|C S|143|F A|144|G A|144|V FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -0.11167965783954788 P07149 0.011831481941044329 0.00555053586140275 0.18655377626419067 0.09256239235401154 57.442314794035546 50.0 1.0 no 6900 chrXI_101201 20815 essential YKL182W 530 + TCAAACTTATCATGTCTTAG Q|178|E Q|178|* T|179|S T|179|I FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 0.004778608741918654 P07149 0.7398994565010071 0.0577976293861866 0.6255781650543213 37.657885493975186 30.0 1.0 no 6901 chrXI_101283 20816 essential YKL182W 612 + GCTGAAAAAGTCTTTACTCA A|205|G A|205|V FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 1.3076403337847546 P07149 0.4840268194675446 0.5963261723518372 39.828697029874775 35.0 1.0 no 6902 chrXI_101333 20817 essential YKL182W 662 + CCCTTCAAATACCCCAGACA P|222|R P|222|L P|222|A P|222|S FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -1.176130850461492 P07149 0.20591485500335693 0.05876486375927925 0.8466702699661255 0.4700318574905396 52.99146602559409 50.0 1.0 no 6903 chrXI_101373 20819 essential YKL182W 702 + CCAATTTCATGCCCCTTAAT P|235|R P|235|L FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 0.6461312446685508 P07149 0.13469421863555908 0.015124517492949963 50.28200486222579 40.0 1.0 no 6904 chrXI_101430 20821 essential YKL182W 759 + AAGCTTTTGGGTTTCACTCC L|255|V L|255|F FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -0.12781901591346442 P07149 1.0 0.023812256753444668 51.57849848875014 45.0 1.0 no 6905 chrXI_101463 20822 essential YKL182W 792 + TCTTACTTAAAAGGTGCTAC S|265|C S|265|F Y|266|* silent|TAC>TAT|Y|266 FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -0.3183654475173364 P07149 0.05431091785430908 0.06045758724212647 39.49442470105839 35.0 1.0 no 6906 chrXI_101480 20823 essential YKL182W 809 + TACAGGTCACTCTCAAGGTT T|271|R T|271|I FAS1 Fatty Acid Synthetase 2051.0 0 1 0 0 -1.3889275469665878 P07149 0.004572596866637468 0.005189165472984314 49.15907840886069 45.0 1.0 no 6907 chrXI_101689r 20827 essential YKL182W 1021 - TTCTTGAGTTAGATTGGAAA E|347|Q E|347|K FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 0.8482187273406107 P07149 0.4888070225715637 0.947261393070221 38.03800689026957 30.0 1.0 no 6908 chrXI_101695r 20828 essential YKL182W 1027 - AACTTGTTCTTGAGTTAGAT V|349|L V|349|I FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 0.18945443703795006 P07149 1.0 0.2460988163948059 40.58065096377408 30.0 1.0 no 6909 chrXI_101650r 20829 essential YKL182W 982 - AACACCTTCATTGTTTTCCA V|334|L V|334|I G|333|A G|333|D FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -0.325895940173184 P07149 0.1849137395620346 0.2085585594177246 0.0 0.0 47.80819937857933 35.0 1.0 no 6910 chrXI_101789 20831 essential YKL182W 1118 + TGCGAAGAATCTAGTCGTAT A|374|G A|374|V FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 0.9460006128429284 P07149 0.19361154735088348 0.067877396941185 42.61664730465452 40.0 1.0 no 6911 chrXI_101814r 20833 essential YKL182W 1146 - AAACCATATAATGATTGTGG G|388|A G|388|D G|388|R G|388|S FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 0.208207936937914 P07149 0.15026092529296875 0.0308437030762434 0.0074283480644226066 0.03579363226890564 36.23765380019012 30.0 1.0 no 6912 chrXI_101891r 20834 essential YKL182W 1223 - TCAATTTTCTTTCGCTGAAT L|414|F silent|TTG>TTA|L|414 FAS1 Fatty Acid Synthetase 2051.0 0 1 0 0 0.5370154019508331 P07149 0.20971426367759705 41.53383610332617 30.0 1.0 no 6913 chrXI_101892r 20835 essential YKL182W 1224 - TTCAATTTTCTTTCGCTGAA L|414|F silent|TTG>TTA|L|414 FAS1 Fatty Acid Synthetase 2051.0 0 1 0 0 0.1422776794458301 P07149 0.20971426367759705 41.78348200692403 30.0 1.0 no 6914 chrXI_101945 20837 essential YKL182W 1274 + ACCATTCCATTCCCATCTAT P|426|R P|426|L P|426|A P|426|S FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -0.15824538801694854 P07149 0.09960350394248962 0.01229730062186718 0.03351141512393952 0.022248243913054463 53.47543259767507 40.0 1.0 no 6915 chrXI_102042 20839 essential YKL182W 1371 + CCCGTTTACGACACTTTTGA silent|CCC>CCG|P|458 silent|CCC>CCT|P|458 P|458|R P|458|L FAS1 Fatty Acid Synthetase 2051.0 0 0 0 1 0.3863547399015512 P07149 0.01627093367278576 0.03722249716520309 49.141885700874006 45.0 1.0 no 6916 chrXI_102042r 20840 essential YKL182W 1374 - CCATCAAAAGTGTCGTAAAC G|465|R G|465|S D|464|H D|464|N FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 0.7803252365782466 P07149 0.004594345577061175 0.1002441942691803 0.035568296909332275 0.2010582536458969 39.30251606840022 40.0 1.0 no 6917 chrXI_102118 20843 essential YKL182W 1447 + TCATTAGATTACCTGTCAAA I|483|M silent|ATC>ATT|I|483 FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 0.8422298217084234 P07149 0.005268496461212635 40.125969841705114 30.0 1.0 no 6918 chrXI_102163r 20845 essential YKL182W 1495 - ACCAAAGTCTAATATGTGGG G|505|R G|505|S G|505|A G|505|D FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -4.285579214341253 P07149 0.0 0.0 0.0 0.0 41.93652539303969 40.0 1.0 yes 6919 chrXI_102411 20852 essential YKL182W 1740 + ACAAAATTTTCTAAATTAAT T|581|R T|581|I FAS1 Fatty Acid Synthetase 2051.0 0 1 0 0 0.4046227920404465 P07149 0.0 0.0 26.795115047334374 10.0 1.0 no 6920 chrXI_102441r 20853 essential YKL182W 1773 - GTCATACCAGGAACCAATAA M|597|I M|597|I G|596|A G|596|D FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -3.9327567534609225 P07149 0.0 0.0 0.0 0.0 43.337637948894546 40.0 1.0 yes 6921 chrXI_102506 20856 essential YKL182W 1835 + TGCTGGTTATACCATTGAGT A|613|G A|613|V FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -0.002318723349700791 P07149 0.0 0.0 48.552363911223715 40.0 1.0 no 6922 chrXI_102517r 20858 essential YKL182W 1849 - ACCACCACCGGCCAACTCAA G|623|R G|623|S G|623|A G|623|D FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -2.912067913438813 P07149 0.003920349758118391 0.025465279817581173 0.10359480232000352 0.005882327910512686 56.8234725034094 60.0 1.0 yes 6923 chrXI_102631 20860 essential YKL182W 1960 + TCAATCCATTTATGTTACAA silent|GTC>GTG|V|654 silent|GTC>GTT|V|654 P|656|A P|656|S FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 0.5149273638827759 P07149 0.4645482897758484 0.21943239867687225 38.71226702642372 25.0 1.0 no 6924 chrXI_102633 20861 essential YKL182W 1962 + AATCCATTTATGTTACAATG P|656|A P|656|S P|656|R P|656|L FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -0.6222153340705774 P07149 0.4645482897758484 0.21943239867687225 0.17165538668632507 0.2221563011407852 36.58679619876659 25.0 1.0 no 6925 chrXI_102636r 20862 essential YKL182W 1968 - ATACCCCATTGTAACATAAA G|662|A G|662|D G|662|R G|662|S FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -0.0639566194413124 P07149 0.22176381945610046 0.07267998158931732 0.04056249931454658 0.13738375902175906 41.208648561100524 30.0 1.0 no 6926 chrXI_102666 20863 essential YKL182W 1995 + ATCAAGGAACTAAGAAGCAA I|666|M silent|ATC>ATT|I|666 FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -0.6200918247740801 P07149 0.10659780353307724 36.27174704243754 35.0 1.0 no 6927 chrXI_102693 20864 essential YKL182W 2022 + CCAATTCAATTCTTGACCAT P|675|R P|675|L Q|677|E Q|677|* FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 0.7979707755642365 P07149 0.0 0.0 1.0 44.046600434583404 35.0 1.0 no 6928 chrXI_102693r 20865 essential YKL182W 2025 - CCAATGGTCAAGAATTGAAT G|682|R G|682|S FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -5.906220844970236 P07149 0.014455326832830906 0.10023646056652068 38.762427058343356 35.0 1.0 yes 6929 chrXI_102725r 20866 essential YKL182W 2057 - CACTAGCAACTTCCAATGAT S|692|T S|692|N A|691|P A|691|T FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -0.3786021808701064 P07149 0.5808513164520264 0.7887744903564453 0.012801675125956535 0.01166137494146824 44.11705322796735 40.0 1.0 no 6930 chrXI_102758 20867 essential YKL182W 2087 + GACATTAGGTTTGAAGTACT T|697|R T|697|I FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -0.7406984604272193 P07149 0.3482024967670441 0.1187075451016426 41.244037927156455 35.0 1.0 no 6931 chrXI_102844 20870 essential YKL182W 2173 + ACTTCCCAATAGCTTTACAA N|725|K silent|AAC>AAT|N|725 F|726|L silent|TTC>TTT|F|726 FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -0.3357589053137494 P07149 0.20415668189525604 0.11368661373853685 45.362928371916276 35.0 1.0 no 6932 chrXI_102908r 20872 essential YKL182W 2240 - ACATTTGTAACATTGGAGTG M|753|I M|753|I FAS1 Fatty Acid Synthetase 2051.0 0 1 0 0 -0.6671933253827245 P07149 0.345339298248291 0.345339298248291 40.0929161991711 35.0 1.0 no 6933 chrXI_102996 20874 essential YKL182W 2325 + GACACTTACCCATACTTAAC D|776|E silent|GAC>GAT|D|776 T|777|S T|777|I FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 0.3717967869175751 P07149 0.03227398544549942 0.0511021800339222 0.09678342938423157 43.98900990994707 40.0 1.0 no 6934 chrXI_103004r 20875 essential YKL182W 2336 - ACCATTCACCGGTTAAGTAT W|785|S W|785|* W|785|C W|785|* FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -4.310858333111134 P07149 0.0 0.0 47.91675849669667 40.0 1.0 yes 6935 chrXI_103041 20877 essential YKL182W 2370 + TATCCACCAATGCCATTCGA P|792|A P|792|S P|792|R P|792|L FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 0.2342726839458394 P07149 0.3226413726806641 0.23404935002326965 0.0593612976372242 0.0373278483748436 50.7833603491286 45.0 1.0 no 6936 chrXI_103053 20878 essential YKL182W 2382 + CCATTCGATGGTTTCCTATT P|795|R P|795|L F|796|L silent|TTC>TTT|F|796 FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 0.036167748003339495 P07149 0.0 0.0 0.0 49.751686351281535 40.0 1.0 no 6937 chrXI_103053r 20879 essential YKL182W 2385 - CCAAATAGGAAACCATCGAA G|802|R G|802|S FAS1 Fatty Acid Synthetase 2051.0 0 1 0 0 -6.818857413606827 P07149 0.006823750212788582 0.046982068568468094 39.81208022370385 40.0 1.0 yes 6938 chrXI_103113r 20882 essential YKL182W 2445 - GCAATACACTTCTTAGCATC A|822|P A|822|T C|820|S C|820|Y FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 0.233752082157075 P07149 0.012936968356370926 0.04425496608018875 0.1321459710597992 0.09715165197849274 44.927111463029966 40.0 1.0 no 6939 chrXI_103173 20883 essential YKL182W 2502 + ACCTACAAGAAGCCAACTGG silent|ACC>ACG|T|835 silent|ACC>ACT|T|835 T|835|S T|835|I FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -0.4977425605811617 P07149 0.0 0.0 46.59482943919778 50.0 1.0 no 6940 chrXI_103185r 20884 essential YKL182W 2517 - ACAGTGACAATACCACCAGT V|846|L V|846|I FAS1 Fatty Acid Synthetase 2051.0 0 1 0 0 -0.9396347100582296 P07149 0.03491280227899552 0.05365095660090447 48.15922812935675 45.0 1.0 no 6941 chrXI_103243r 20887 essential YKL182W 2575 - CCATAGCATAACACCACGAG W|865|S W|865|* M|863|I M|863|I FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -1.2510373285551293 P07149 0.0 0.2154943197965622 0.2154943197965622 46.85447387545099 50.0 1.0 no 6942 chrXI_103289 20889 essential YKL182W 2618 + CAACTTACCAAAGAATAAGT N|874|K silent|AAC>AAT|N|874 FAS1 Fatty Acid Synthetase 2051.0 0 1 0 0 -0.2071901785543619 P07149 0.7834655642509459 34.88001166090902 30.0 1.0 no 6943 chrXI_103314r 20890 essential YKL182W 2646 - TCTCTCTTTGCTTCCAAAGT R|888|T R|888|K D|889|H D|889|N FAS1 Fatty Acid Synthetase 2051.0 0 1 0 0 -0.6593860252561644 P07149 0.034727726131677635 1.0 0.03071144223213196 0.25625190138816833 49.8282460360889 40.0 1.0 no 6944 chrXI_103374 20892 essential YKL182W 2703 + CCATGGTTTGCTACCGTCAA P|902|R P|902|L FAS1 Fatty Acid Synthetase 2051.0 0 1 0 0 0.0679462250463864 P07149 0.08396326005458833 0.3873265981674193 53.158966132713836 50.0 1.0 no 6945 chrXI_103402r 20895 essential YKL182W 2734 - TGTCATTGTGGCTAGGTCAC M|917|I M|917|I FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -2.5449313968620846 P07149 0.0 0.0 52.67217267519232 50.0 1.0 yes 6946 chrXI_103409r 20896 essential YKL182W 2741 - CTTCGTATGTCATTGTGGCT E|920|Q E|920|K FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 0.5808019623249591 P07149 0.4565145969390869 0.6483128070831299 51.30608556396453 45.0 1.0 no 6947 chrXI_103462 20897 essential YKL182W 2791 + TCATCAGATCTACCAACTCT F|931|L silent|TTC>TTT|F|931 I|932|M silent|ATC>ATT|I|932 FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 0.4238023409380614 P07149 0.11232159286737442 0.012884953990578651 46.53234815571096 40.0 1.0 no 6948 chrXI_103504r 20899 essential YKL182W 2836 - ACGTAGGAAATCACCAGTAA R|952|P R|952|H FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -0.3140652226813092 P07149 0.009098993614315987 0.09899324923753737 42.07468977550951 40.0 1.0 no 6949 chrXI_103596r 20902 essential YKL182W 2928 - ACTTTTTCAATAGCTTCATC V|983|L V|983|I FAS1 Fatty Acid Synthetase 2051.0 0 1 0 0 0.26183960309912 P07149 0.7773563861846924 0.444892168045044 41.66175810238785 30.0 1.0 no 6950 chrXI_103636r 20903 essential YKL182W 2968 - ATTCAAGAACTGTTCCCTAG L|995|F silent|TTG>TTA|L|995 FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -0.20999405800220367 P07149 0.03688646480441093 45.04663902689288 40.0 1.0 no 6951 chrXI_103805r 20905 essential YKL182W 3137 - TACATGTTCTTTGAACGTCT C|1052|S C|1052|Y FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -1.6263023206973406 P07149 0.06494349241256714 0.023494919762015343 43.20201702437986 35.0 1.0 no 6952 chrXI_103875 20907 essential YKL182W 3204 + CCAATTAAGAGCATTATGGA P|1069|R P|1069|L FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -0.3968627029483558 P07149 0.0049824248999357215 0.005264168605208397 40.8398036933279 35.0 1.0 no 6953 chrXI_103962r 20909 essential YKL182W 3294 - CCACCAAAGTACTCAACTGC G|1104|A G|1104|D G|1105|R G|1105|S FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -0.03494364642061601 P07149 0.3883318305015564 0.31068944931030273 0.4393621683120728 0.8873925209045409 47.71664706045278 50.0 1.0 no 6954 chrXI_103992r 20910 essential YKL182W 3324 - ACTTGACTTTGTACGTCTAC V|1115|L V|1115|I S|1113|T S|1113|N FAS1 Fatty Acid Synthetase 2051.0 0 1 0 0 0.21052609629566293 P07149 0.7522151470184326 0.7868080139160156 0.588497519493103 0.4953995645046234 44.61160958321068 40.0 1.0 no 6955 chrXI_104104r 20915 essential YKL182W 3436 - TGCATGTCTCCAGTTAATTT A|1152|P A|1152|T FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -0.1011346665060257 P07149 0.0 0.0 47.03588183586471 35.0 1.0 no 6956 chrXI_104175r 20916 essential YKL182W 3507 - GGCTTGAAAACTTTTCTAAT K|1175|N silent|AAG>AAA|K|1175 FAS1 Fatty Acid Synthetase 2051.0 0 1 0 0 0.5125097970266553 P07149 0.2783666253089905 38.11174470346458 30.0 1.0 no 6957 chrXI_104196r 20918 essential YKL182W 3528 - TCAACAACCATTCCTTGGCT E|1183|Q E|1183|K V|1182|L V|1182|I FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -1.2927874787735505 P07149 0.5782113671302795 0.9107084274291992 0.23611652851104736 0.07873228192329408 50.569321058294584 45.0 1.0 no 6958 chrXI_103875r 20919 essential YKL182W 3207 - CCATCCATAATGCTCTTAAT G|1076|R G|1076|S D|1075|H D|1075|N FAS1 Fatty Acid Synthetase 2051.0 0 1 0 0 -0.553491808959111 P07149 0.20399078726768494 0.362271249294281 0.10637328773736954 0.5583625435829163 44.867770276909425 35.0 1.0 no 6959 chrXI_104414 20921 essential YKL182W 3743 + TGCTCCAATCTCTGAAGTTA A|1249|G A|1249|V P|1250|A P|1250|S FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 0.21175322900585256 P07149 0.024828465655446053 0.15822453796863556 0.045977450907230384 0.159279465675354 46.935302699640495 40.0 1.0 no 6960 chrXI_104368r 20922 essential YKL182W 3700 - GTACAACAATGGCAAGCTGA L|1239|F silent|TTG>TTA|L|1239 L|1238|F silent|TTG>TTA|L|1238 FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -0.05651144578124188 P07149 0.7026194930076599 0.3756048977375031 44.254007583629466 45.0 1.0 no 6961 chrXI_104388 20923 essential YKL182W 3717 + TACAACTTCAACCCAGATAA Y|1240|* silent|TAC>TAT|Y|1240 N|1241|K silent|AAC>AAT|N|1241 FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 0.10103394660567463 P07149 0.90695720911026 41.169059451539226 35.0 1.0 no 6962 chrXI_104507 20927 essential YKL182W 3836 + TGACCCAAGAGATGTCATTA D|1280|E silent|GAC>GAT|D|1280 P|1281|A P|1281|S FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 0.7839111130566152 P07149 1.0 0.5608153939247131 0.2468899637460709 45.39707580660003 40.0 1.0 no 6963 chrXI_104632r 20929 essential YKL182W 3964 - AACAATAGCAAAGTCCATTG V|1328|L V|1328|I FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -0.29641171901531144 P07149 0.0 0.0 38.77562095142115 35.0 1.0 no 6964 chrXI_104641 20930 essential YKL182W 3970 + ACTTTGCTATTGTTGTCGGA D|1324|E silent|GAC>GAT|D|1324 A|1326|G A|1326|V FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 0.3066050347781298 P07149 0.0 0.22400696575641632 0.011805560439825058 48.435538359355284 40.0 1.0 no 6965 chrXI_104687r 20931 essential YKL182W 4019 - AGTCACCATCGACCGTATTA D|1346|H D|1346|N G|1345|A G|1345|D FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 0.4394257156201423 P07149 0.00791726168245077 0.1291869580745697 0.3069460391998291 0.00687279412522912 50.104282160060215 45.0 1.0 no 6966 chrXI_104733 20932 essential YKL182W 4062 + AACGGCTACAAGATGATTCC N|1355|K silent|AAC>AAT|N|1355 silent|GGC>GGG|G|1356 silent|GGC>GGT|G|1356 FAS1 Fatty Acid Synthetase 2051.0 0 1 0 0 -0.27479890098963344 P07149 0.02252771332859993 44.49649893044193 45.0 1.0 no 6967 chrXI_104808 20935 essential YKL182W 4137 + TCTGTCGTCAACCAACCTAC S|1380|C S|1380|F silent|GTC>GTG|V|1381 silent|GTC>GTT|V|1381 FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -0.5064326392574799 P07149 0.01944156177341938 0.007784957997500896 49.94738919737415 50.0 1.0 no 6968 chrXI_104763r 20936 essential YKL182W 4095 - ACAACATCACCAACTTGCAG V|1372|L V|1372|I V|1371|L V|1371|I FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -0.6654151126752537 P07149 0.3671218156814575 0.4751986563205719 0.08996272087097168 0.1956176608800888 45.11327313385721 45.0 1.0 no 6969 chrXI_105005 20939 essential YKL182W 4334 + CTCTAAGGAGTGGTTCCAAT S|1446|C S|1446|F FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -0.2415926294777321 P07149 0.006845744326710701 0.0027975684497505426 47.894313917512314 45.0 1.0 no 6970 chrXI_105108 20940 essential YKL182W 4437 + TTCTCTTCAGTGAAATGTTT F|1480|L silent|TTC>TTT|F|1480 S|1481|C S|1481|F FAS1 Fatty Acid Synthetase 2051.0 0 1 0 0 0.24968280570256404 P07149 0.14949853718280792 0.030287666246294975 0.025550130754709244 41.24561565942384 30.0 1.0 no 6971 chrXI_105153 20941 essential YKL182W 4482 + ACCAAAGAAACCGTGGAGAT silent|ACC>ACG|T|1495 silent|ACC>ACT|T|1495 T|1495|S T|1495|I FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -0.06205808082518735 P07149 0.2715941369533539 0.5161877870559692 43.13372073992645 45.0 1.0 no 6972 chrXI_105163r 20942 essential YKL182W 4495 - ATCGACAATACCGATCTCCA D|1505|H D|1505|N V|1504|L V|1504|I FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -2.2422564406813006 P07149 0.026532471179962158 0.4592633247375488 0.030963625758886337 0.30546894669532776 47.68289206683835 45.0 1.0 yes 6973 chrXI_105186 20943 essential YKL182W 4515 + TACGAAGCCGGTGCCTCTCA Y|1506|* silent|TAC>TAT|Y|1506 FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -3.860707618461 P07149 57.34622505192994 60.0 1.0 yes 6974 chrXI_105213r 20945 essential YKL182W 4545 - CTCTTCAAGAAATCAACAAC K|1521|N silent|AAG>AAA|K|1521 L|1520|F silent|TTG>TTA|L|1520 FAS1 Fatty Acid Synthetase 2051.0 0 1 0 0 0.03725377653959525 P07149 0.2001955509185791 0.01636974886059761 35.270538586457235 35.0 1.0 no 6975 chrXI_105282r 20947 essential YKL182W 4614 - TACGAATCAAGTACTGCAAT silent|TCG>TCC|S|1544 silent|TCG>TCA|S|1544 FAS1 Fatty Acid Synthetase 2051.0 0 0 0 0 -0.09136157862217063 P07149 38.95856852969172 35.0 1.0 no 6976 chrXI_109364 20951 essential YKL180W 95 + TGCTCAAGCTATTAACGGTT A|33|G A|33|V Q|34|E Q|34|* 0 0 0 0 0.5971297809382258 P05740 0.9484469890594482 0.9504740238189696 0.9590039849281312 0.09936852008104324 0.03628668561577797 0.5224614143371582 0.7344800233840942 1.6969399452209473 0.5504999756813049 45.46518847496702 40.0 1.0 no 6977 chrXI_109465r 20954 essential YKL180W 199 - ACCTTGAGCAGTTCTACCGA G|73|R G|73|S G|73|A G|73|D 0 1 0 0 -1.0714286979889025 P05740 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0022055236622691154 0.01633578538894653 1.0 0.0023202437441796064 7.368060111999513 1.338379979133606 -0.1046999990940094 9.386019706726074 53.600977584787756 50.0 1.0 no 6978 chrXI_109934r 20955 essential YKL180W 362 - TTCTTCTTTGCTTTGGAGCT R|127|T R|127|K R|126|T R|126|K 0 0 0 0 0.06853387885962009 P05740 0.932735025882721 0.955805003643036 0.932735025882721 0.955805003643036 0.0065504610538482675 0.03503422811627388 0.014474472962319853 0.05070383101701737 1.955979943275452 -0.02662000060081482 -0.0982000008225441 -0.07902000099420547 51.58901335670817 40.0 1.0 no 6979 chrXI_122568r 20956 essential YKL173W 54 - TCTTCTTCATCCGAGTCAAA E|25|Q E|25|K E|24|Q E|24|K SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 0.34517275792533925 P36048 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.4542386531829834 0.4906865060329437 0.4558733701705933 0.6473087072372437 46.760217391472615 40.0 1.0 no 6980 chrXI_122616 20957 essential YKL173W 99 + TATCAAACCAATACGTTTGA Q|35|E Q|35|* SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 0.08652569186440134 P36048 0.9590039849281312 1.0 38.05738036243184 30.0 1.0 no 6981 chrXI_122617 20958 essential YKL173W 100 + ATCAAACCAATACGTTTGAG Q|35|E Q|35|* T|36|S T|36|I SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 -3.18003489402304 P36048 0.9590039849281312 0.9491789937019348 0.9472420215606691 1.0 0.7328311204910278 0.18827326595783234 38.5752378641471 35.0 1.0 yes 6982 chrXI_122664 20960 essential YKL173W 147 + AGCAGACAACTTACCTCGTT S|50|R silent|AGC>AGT|S|50 Q|52|E Q|52|* SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 0.5863607310972918 P36048 0.9417110085487366 0.9590039849281312 0.5140612721443176 0.7199652194976807 48.77284949805693 45.0 1.0 no 6983 chrXI_122623r 20961 essential YKL173W 109 - GCCGCTCCCCTCAAACGTAT G|43|R G|43|S G|43|A G|43|D SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 -0.35611425616269976 P36048 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.496465265750885 0.6928558349609375 0.7645511031150818 0.6027761101722717 58.84311020227108 60.0 1.0 no 6984 chrXI_122720r 20962 essential YKL173W 206 - CTTCCACTTCCTTACCATAA E|75|Q E|75|K silent|GTG>GTC|V|74 silent|GTG>GTA|V|74 SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 0.06879902589499773 P36048 0.956179976463318 0.9475290179252625 0.04185841232538223 0.034224726259708405 49.67281344616532 40.0 1.0 no 6985 chrXI_122721r 20963 essential YKL173W 207 - ACTTCCACTTCCTTACCATA V|76|L V|76|I E|75|Q E|75|K SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 0.004904005337732525 P36048 0.9539830088615416 0.9574310183525084 0.956179976463318 0.9475290179252625 0.16921742260456085 0.4363765120506287 0.04185841232538223 0.034224726259708405 51.778651297275864 40.0 1.0 no 6986 chrXI_122772r 20964 essential YKL173W 258 - GGCTCTACCAGTGGAGTCTG E|92|D silent|GAG>GAA|E|92 E|92|Q E|92|K SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 1 0 0 -1.947885587962968 P36048 0.94931298494339 0.956179976463318 0.9475290179252625 0.27211835980415344 0.40574780106544495 1.0 57.606020035975114 60.0 1.0 no 6987 chrXI_122765 20965 essential YKL173W 248 + ACAGTCACCACAGACTCCAC Q|84|E Q|84|* S|85|* S|85|L SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 1 0 0 -0.9908447652581059 P36048 0.9590039849281312 0.9298099875450134 0.3408056199550629 0.24372147023677826 53.512283744793024 55.00000000000001 1.0 no 6988 chrXI_122793r 20968 essential YKL173W 279 - AACTTTGTTCGTTCTGTAAC K|99|N silent|AAG>AAA|K|99 SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 0.38745716878797215 P36048 0.9355990290641784 0.500200629234314 41.907288751504105 35.0 1.0 no 6989 chrXI_122856r 20969 essential YKL173W 342 - TCTCGATTATATCTAGTCTT R|120|P R|120|Q D|121|H D|121|N SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 0.12114340607786425 P36048 0.9099509716033936 0.949662983417511 0.9486550092697144 0.956179976463318 0.024769112467765808 0.07385391741991043 0.01659090630710125 0.2817248106002808 42.33567033267929 30.0 1.0 no 6990 chrXI_122873 20970 essential YKL173W 356 + TCGAGACTATATGTTATCAA R|120|G R|120|* D|121|E silent|GAC>GAT|D|121 SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 0.14862598952747752 P36048 0.8994590044021606 0.9532920122146606 0.02267223410308361 0.4771391451358795 38.114494233874545 30.0 1.0 no 6991 chrXI_122904r 20972 essential YKL173W 390 - CCAACATTTATTATCCTCTC G|137|R G|137|S V|136|L V|136|I SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 -1.5372043224577154 P36048 0.941340982913971 0.951104998588562 0.9539830088615416 0.9574310183525084 0.011274163611233234 0.17289401590824127 0.2118857353925705 0.7961596250534058 44.717521402260964 35.0 1.0 no 6992 chrXI_122945 20973 essential YKL173W 428 + CTCAGGTAAGACCTCTTTGA S|144|* S|144|L SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 -5.122865310671559 P36048 0.9298099875450134 0.043290656059980386 48.29007340654221 45.0 1.0 yes 6993 chrXI_123000r 20975 essential YKL173W 486 - TCTACATTCTTAGACATATC E|169|Q E|169|K V|168|L V|168|I SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 -0.1243341575581669 P36048 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.5417030453681946 0.8424490690231323 0.4327093362808228 0.3524510860443115 39.11069476782603 30.0 1.0 no 6994 chrXI_123134 20977 essential YKL173W 617 + GTCTAGAATGATAAACTTTT S|207|C S|207|F SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 0.8734255407900317 P36048 0.945252001285553 0.9294660091400146 0.004232018254697323 0.002165670972317457 34.53952563381057 25.0 1.0 no 6995 chrXI_123161 20978 essential YKL173W 644 + ACCAGGGCATGTTAATTTTA P|216|R P|216|L P|216|A P|216|S SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 -1.1839423176793331 P36048 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 45.57141009543949 35.0 1.0 no 6996 chrXI_123162r 20979 essential YKL173W 648 - TCCATAAAATTAACATGCCC M|222|I M|222|I D|223|H D|223|N SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 -0.7798690891876232 P36048 0.9553959965705872 0.9553959965705872 0.9486550092697144 0.956179976463318 0.3894192576408386 0.3894192576408386 0.0 0.0 41.88036010375913 35.0 1.0 no 6997 chrXI_123354r 20982 essential YKL173W 840 - TTCAAGTATGCGTCCATTGG L|286|F silent|TTG>TTA|L|286 SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 0.4474765630689557 P36048 0.9587849974632264 0.8033401370048523 48.45707157866281 45.0 1.0 no 6998 chrXI_123406r 20984 essential YKL173W 892 - AAACACGTTTCCCTTCGTAA silent|GTG>GTC|V|303 silent|GTG>GTA|V|303 V|303|L V|303|M SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 0.9107923375199068 P36048 0.9539830088615416 0.9587630033493042 0.7169574499130249 0.22613956034183505 45.93214085924786 40.0 1.0 no 6999 chrXI_123470 20985 essential YKL173W 953 + GGGCTTCACATTCACTATCA silent|GGC>GGG|G|319 silent|GGC>GGT|G|319 F|320|L silent|TTC>TTT|F|320 SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 0.3327349445797149 P36048 0.9387490153312684 0.06555904448032379 50.668215293112716 45.0 1.0 no 7000 chrXI_123541 20987 essential YKL173W 1024 + ACGACTTTACCACAAGGCTA D|342|E silent|GAC>GAT|D|342 D|343|E silent|GAC>GAT|D|343 SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 -0.16482559911640204 P36048 0.9532920122146606 0.9532920122146606 1.0 1.0 47.39568128014332 45.0 1.0 no 7001 chrXI_123542 20988 essential YKL173W 1025 + CGACTTTACCACAAGGCTAT D|343|E silent|GAC>GAT|D|343 SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 -0.4962904774537672 P36048 0.9532920122146606 1.0 46.95794507300957 45.0 1.0 no 7002 chrXI_123550r 20990 essential YKL173W 1036 - TACGCTACCCCATAGCCTTG V|352|L V|352|I S|351|T S|351|N SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 1 0 0 -0.13984791319864434 P36048 0.9539830088615416 0.9574310183525084 0.9512869715690612 0.9536849856376648 0.2604461908340454 1.0 0.048062764108181 0.4043503105640411 56.66346359682036 55.00000000000001 1.0 no 7003 chrXI_123603r 20991 essential YKL173W 1089 - TACTTCTCTACATTTTCAAA K|369|N silent|AAG>AAA|K|369 E|368|D silent|GAG>GAA|E|368 SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 0.853357301170677 P36048 0.9355990290641784 0.94931298494339 0.4936304986476898 0.5820792317390442 37.96706422347955 25.0 1.0 no 7004 chrXI_123784 20994 essential YKL173W 1267 + ACGTTCTACAGTTAATATTT H|423|Q silent|CAC>CAT|H|423 L|425|V silent|CTA>TTA|L|425 SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 0.7470692919734784 P36048 0.9588389992713928 0.9512209892272948 0.31485942006111145 0.19334261119365687 38.35188373686094 25.0 1.0 no 7005 chrXI_123835r 20996 essential YKL173W 1321 - TTCAAATGGTTGATAACATC E|447|Q E|447|K SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 0.5489786928980922 P36048 0.956179976463318 0.9475290179252625 0.6064201593399048 0.7626081705093384 36.04900387824751 30.0 1.0 no 7006 chrXI_123891r 20997 essential YKL173W 1377 - CCTTCTGGTGTAGATTTTCC G|466|R G|466|S E|465|Q E|465|K SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 0.058551157568893474 P36048 0.941340982913971 0.951104998588562 0.956179976463318 0.9475290179252625 0.27709707617759705 0.4015222489833832 0.5101261138916016 0.6751676201820374 52.19862796501195 45.0 1.0 no 7007 chrXI_123902 21000 essential YKL173W 1385 + TACACCAGAAGGCACTCTTT T|463|R T|463|I P|464|A P|464|S SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 1.1047065043162487 P36048 0.9476869702339172 0.9472420215606691 0.9562489986419678 0.9498909711837769 0.1571657806634903 0.09489659965038301 0.7327502369880676 0.8137742877006531 48.794439850107146 45.0 1.0 no 7008 chrXI_123967r 21003 essential YKL173W 1453 - TCCAGAGTATATCCGTACAA G|491|R G|491|R G|491|A G|491|E SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 0.5479646605914604 P36048 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.0 0.0 0.0 0.0 46.34519129143092 40.0 1.0 no 7009 chrXI_123981 21004 essential YKL173W 1464 + TACTCTGGACTTTTGAAGAG Y|489|* silent|TAC>TAT|Y|489 S|490|C S|490|F SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 -0.8447849421202751 P36048 0.945252001285553 0.9294660091400146 0.01991668716073036 0.03068462386727333 41.3339687598048 40.0 1.0 no 7010 chrXI_124084r 21007 essential YKL173W 1570 - TTCATCTTCATCTTCGTTGG E|530|Q E|530|K D|529|H D|529|N SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 0.12786708913695394 P36048 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.13994503021240234 0.17843052744865415 0.22080734372138974 0.5513529777526855 47.795638791998726 40.0 1.0 no 7011 chrXI_124170 21010 essential YKL173W 1653 + CCGGTTCATGAAGCACACAA P|552|R P|552|L H|554|D H|554|Y SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 -0.2481183691869234 P36048 0.9432820081710817 0.9430609941482544 0.9473130106925964 0.9489949941635132 0.02582391165196896 0.017977800220251083 0.6514394879341125 0.03396132960915565 48.184970017648475 50.0 1.0 no 7012 chrXI_124333 21013 essential YKL173W 1816 + TTCTTCAACCTTTACTGCCA L|607|V L|607|F Q|608|E Q|608|* SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 0.6592838691551249 P36048 0.9512209892272948 0.9587849974632264 0.9590039849281312 0.9443090558052064 0.04353167116641998 1.0 50.428096423354816 40.0 1.0 no 7013 chrXI_124403r 21015 essential YKL173W 1889 - CAACTTTAATAATAACGCCT V|636|L V|636|I SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 0.3947696859567104 P36048 0.9539830088615416 0.9574310183525084 0.13843412697315216 0.17868325114250186 37.577124471726734 30.0 1.0 no 7014 chrXI_124404r 21016 essential YKL173W 1890 - TCAACTTTAATAATAACGCC E|637|Q E|637|K V|636|L V|636|I SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 1.6810332490180555 P36048 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.0 0.0 0.13843412697315216 0.17868325114250186 36.71646990565876 30.0 1.0 no 7015 chrXI_124406 21017 essential YKL173W 1889 + AGGCGTTATTATTAAAGTTG silent|GGC>GGG|G|631 silent|GGC>GGT|G|631 SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 -0.28785018590979466 P36048 38.10033423057189 30.0 1.0 no 7016 chrXI_124431 21018 essential YKL173W 1914 + TCTGGAGAACATGTAATACT S|639|C S|639|F SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 0.8952781924084611 P36048 0.945252001285553 0.9294660091400146 0.0 0.0 39.3349830543674 35.0 1.0 no 7017 chrXI_124595 21020 essential YKL173W 2078 + TTCGATATCTCGCCTTGGTG S|694|W S|694|L SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 0.34894503447447145 P36048 0.9288619756698608 0.9298099875450134 0.015526110306382181 0.17318765819072726 51.735871076344786 50.0 1.0 no 7018 chrXI_124759r 21024 essential YKL173W 2245 - ATACTCGGTTCTCAATATTT E|754|D silent|GAG>GAA|E|754 E|754|Q E|754|K SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 0.6020414405055066 P36048 0.94931298494339 0.956179976463318 0.9475290179252625 0.3933290541172028 0.2299235910177231 0.3610366582870483 41.8281172305999 30.0 1.0 no 7019 chrXI_124774r 21025 essential YKL173W 2260 - CAACGAATCCCACCCATACT silent|TCG>TCC|S|759 silent|TCG>TCA|S|759 SNU114 Small NUclear ribonucleoprotein associated 1008.0 0 0 0 0 -0.225190620829824 P36048 50.56647334666423 50.0 1.0 no 7020 chrXI_125854r 21026 essential YKL172W 98 - GTTCTTCTTTCTTCAATTCT E|39|Q E|39|K E|38|Q E|38|K EBP2 EBNA1-binding protein (homolog) 427.0 0 1 0 0 0.6435777979827593 P36049 1.0002599954605105 0.9889079928398132 1.0002599954605105 0.9889079928398132 45.37827786551446 30.0 1.0 no 7021 chrXI_125931r 21027 essential YKL172W 175 - AGCAACTTCCTTCTTAACAT A|65|P A|65|T V|64|L V|64|I EBP2 EBNA1-binding protein (homolog) 427.0 0 1 0 0 0.4757238183768056 P36049 1.000890016555786 0.9932940006256104 0.9938480257987976 1.0008200407028198 0.3619289994239807 0.7291221022605896 0.8089384436607361 0.5368778109550476 44.90482802331621 35.0 1.0 no 7022 chrXI_126281r 21029 essential YKL172W 525 - TCAAATTCCACGTCTGACAA D|182|H D|182|N EBP2 EBNA1-binding protein (homolog) 427.0 0 1 0 0 0.2485863844450289 P36049 0.965224027633667 0.97645902633667 0.03829066827893257 0.07555009424686432 43.41373750404325 40.0 1.0 no 7023 chrXI_126339r 21030 essential YKL172W 583 - CATCGCTTTTGTGTTGTTGA silent|GCG>GCC|A|200 silent|GCG>GCA|A|200 A|200|P A|200|T EBP2 EBNA1-binding protein (homolog) 427.0 0 0 0 0 0.04677851113252035 P36049 0.9636600017547609 0.9571999907493592 0.0 0.0 48.4364386117215 40.0 1.0 no 7024 chrXI_126490 21031 essential YKL172W 731 + AGCATTTTACAAGCAATCAC A|245|G A|245|V EBP2 EBNA1-binding protein (homolog) 427.0 0 0 0 0 -0.463357197044145 P36049 0.9519839882850648 0.9512100219726562 0.0773485079407692 0.008496301248669623 40.99956071952619 35.0 1.0 no 7025 chrXI_130655 21032 high_effect YKL170W 21 + ATCAAGGTAATCGACAATTC I|8|M silent|ATC>ATT|I|8 MRPL38 Mitochondrial Ribosomal Protein, Large subunit 138.0 0 0 0 0 0.5227572457320963 P35996 0.9598389863967896 0.1775633990764618 38.088086274522254 35.0 1.0 no 7026 chrXI_130720r 21034 high_effect YKL170W 89 - CAACCATTGCAGGACTCTTG V|36|L V|36|I M|35|I M|35|I MRPL38 Mitochondrial Ribosomal Protein, Large subunit 138.0 0 0 0 0 -1.0583587057073944 P35996 0.9539830088615416 0.9574310183525084 0.9553959965705872 0.9553959965705872 0.19121386110782626 1.0 0.4046388864517212 0.4046388864517212 0.987600028514862 3.033799886703491 -0.012199999764561651 -0.012199999764561651 48.72811510392745 50.0 1.0 no 7027 chrXI_130730r 21036 high_effect YKL170W 99 - ATTCTGTCTCCAACCATTGC R|39|T R|39|K MRPL38 Mitochondrial Ribosomal Protein, Large subunit 138.0 0 0 0 0 0.17240754599525274 P35996 0.932735025882721 0.955805003643036 0.4199528694152832 1.0 51.85196560429273 45.0 1.0 no 7028 chrXI_130778 21037 high_effect YKL170W 144 + CCCTTGACTCAAAACATTAC silent|CCC>CCG|P|49 silent|CCC>CCT|P|49 P|49|R P|49|L MRPL38 Mitochondrial Ribosomal Protein, Large subunit 138.0 0 0 0 0 0.17089281726149552 P35996 0.9432820081710817 0.9430609941482544 0.0061927735805511475 0.0061895293183624744 42.31497822982578 40.0 1.0 no 7029 chrXI_130808 21039 high_effect YKL170W 174 + AACACCAACCGTGTCAAAAA N|59|K silent|AAC>AAT|N|59 T|60|S T|60|I MRPL38 Mitochondrial Ribosomal Protein, Large subunit 138.0 0 1 0 0 -0.00123442622301243 P35996 0.9439849853515624 0.9491789937019348 0.9472420215606691 0.811613917350769 0.7490605115890503 0.2940722107887268 40.99149556949533 40.0 1.0 no 7030 chrXI_130896r 21040 high_effect YKL170W 265 - AGCAGTATCTCCGAATGCAA A|95|P A|95|T MRPL38 Mitochondrial Ribosomal Protein, Large subunit 138.0 0 0 0 0 0.017530051134233702 P35996 0.9573720097541808 0.9523990154266356 0.004967502318322658 0.00381252565421164 9.824000358581543 3.77020001411438 48.13992531161495 45.0 1.0 no 7031 chrXI_138643r 21044 essential YKL165C 2026 + TCTCTTTACAGCTAAGACAA S|677|C S|677|F I|676|M silent|ATC>ATT|I|676 MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 0.530634591464046 P36051 0.945252001285553 0.9294660091400146 0.9598389863967896 0.0028012597467750307 0.013050529174506664 0.11876779049634932 41.48072826667175 35.0 0.0 no 7032 chrXI_138644r 21045 essential YKL165C 2025 + ATCTCTTTACAGCTAAGACA I|676|M silent|ATC>ATT|I|676 S|677|C S|677|F MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 0.6963849658543028 P36051 0.9598389863967896 0.945252001285553 0.9294660091400146 0.11876779049634932 0.0028012597467750307 0.013050529174506664 42.98129563153275 35.0 0.0 no 7033 chrXI_138914r 21048 essential YKL165C 1755 + GCGTTTTACCCGTTTATTTG A|586|G A|586|V MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 0.5828611180991028 P36051 0.9484469890594482 0.9504740238189696 0.5633178353309631 0.17461249232292175 49.02762513438938 40.0 0.0 no 7034 chrXI_138992r 21049 essential YKL165C 1677 + TCTATTATATCAGTTTATGA S|560|C S|560|F MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 0.7045097658023198 P36051 0.945252001285553 0.9294660091400146 0.18025542795658112 0.7126802802085876 36.11011968525838 20.0 0.0 no 7035 chrXI_138993r 21050 essential YKL165C 1676 + CTCTATTATATCAGTTTATG S|560|C S|560|F MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 0.8846394332574747 P36051 0.945252001285553 0.9294660091400146 0.18025542795658112 0.7126802802085876 36.771265276049796 25.0 0.0 no 7036 chrXI_139036r 21051 essential YKL165C 1633 + TCTTCAAAGGTACCTCTCCT F|545|L silent|TTC>TTT|F|545 F|546|L silent|TTC>TTT|F|546 MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 -0.5837666666937735 P36051 0.9387490153312684 0.9387490153312684 1.0 0.8008961677551271 51.710826881318035 45.0 0.0 no 7037 chrXI_139174 21052 essential YKL165C 1498 - CCAATTTAGTAAAATTCCTA W|506|S W|506|* MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 -0.7547168995767368 P36051 0.8858469724655151 0.4189465641975403 37.24853247076021 25.0 0.0 no 7038 chrXI_139199 21053 essential YKL165C 1473 - CCAAATACTGCATGGCTTAA G|498|R G|498|S MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 0.7277329911643935 P36051 0.941340982913971 0.951104998588562 0.4040258526802063 0.5868992209434509 44.09244324171448 40.0 0.0 no 7039 chrXI_139199r 21054 essential YKL165C 1470 + CCATTAAGCCATGCAGTATT P|491|R P|491|L MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 -1.3179866311690571 P36051 0.9432820081710817 0.9430609941482544 0.4328142702579498 0.7261770367622375 48.584573590191724 40.0 0.0 no 7040 chrXI_139212 21055 essential YKL165C 1460 - GGCTTAATGGTGACGCTTTT S|493|T S|493|N MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 0.8215915711236399 P36051 0.9512869715690612 0.9536849856376648 0.8010364174842834 0.4372590482234955 49.258870671573106 45.0 0.0 no 7041 chrXI_139324 21056 essential YKL165C 1348 - TCTAATGAATCTCCAATTAT R|456|T R|456|K MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 0.4141669784117775 P36051 0.932735025882721 0.955805003643036 0.004499318078160286 0.07450485229492188 37.07518807128696 25.0 0.0 no 7042 chrXI_139432 21059 essential YKL165C 1240 - TTCAGATATACGCTGAATTA E|420|Q E|420|K MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 0.6231737696027709 P36051 0.956179976463318 0.9475290179252625 0.5731884837150574 0.922730565071106 38.66904608675793 30.0 0.0 no 7043 chrXI_139616r 21060 essential YKL165C 1053 + TTACCAATAGCATATATCGA P|353|A P|353|S P|353|R P|353|L MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 0.05209672651286723 P36051 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.0 0.0 0.0 0.0 40.05553304735315 30.0 0.0 no 7044 chrXI_139643r 21061 essential YKL165C 1026 + AACTATCCTAAAAATTCAGT N|343|K silent|AAC>AAT|N|343 P|345|A P|345|S MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 0.530818373847395 P36051 0.9439849853515624 0.9562489986419678 0.9498909711837769 0.2678713202476501 0.0 0.0 35.25687537865974 25.0 0.0 no 7045 chrXI_139637 21062 essential YKL165C 1035 - AACTCACCAACTGAATTTTT E|351|D silent|GAG>GAA|E|351 E|351|Q E|351|K MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 0.12829939040923424 P36051 0.94931298494339 0.956179976463318 0.9475290179252625 0.254460871219635 0.2977368235588074 0.2802242636680603 39.68007195054855 30.0 0.0 no 7046 chrXI_139670r 21063 essential YKL165C 999 + TCTTTAATGTCATACTTGAT S|334|C S|334|F MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 -0.0212390545890902 P36051 0.945252001285553 0.9294660091400146 0.03425956517457962 0.013939020223915577 38.25590100953775 25.0 0.0 no 7047 chrXI_139741 21064 essential YKL165C 931 - CCAATTTTCAGTATAGTTGT W|317|S W|317|* MCD4 Morphogenesis Checkpoint Dependent 919.0 0 1 0 0 -0.2702230411980575 P36051 0.8858469724655151 0.0 42.67994252313423 30.0 0.0 no 7048 chrXI_139741r 21066 essential YKL165C 928 + CCGACAACTATACTGAAAAT silent|TCC>TCG|S|310 silent|TCC>TCT|S|310 D|311|E silent|GAC>GAT|D|311 MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 1 -0.3473981944692131 P36051 0.9532920122146606 0.1803392320871353 37.03508622094915 35.0 0.0 no 7049 chrXI_139748 21067 essential YKL165C 924 - TCAGTATAGTTGTCGGATAC E|315|Q E|315|K MCD4 Morphogenesis Checkpoint Dependent 919.0 0 1 0 0 0.05357957114803119 P36051 0.956179976463318 0.9475290179252625 0.3607856631278992 0.8078630566596985 44.03866536745329 40.0 0.0 no 7050 chrXI_139767r 21068 essential YKL165C 902 + ACCAGTACATAATCCTTTTC P|302|R P|302|L P|302|A P|302|S MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 -0.7680846129509082 P36051 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 44.95666316217257 35.0 0.0 no 7051 chrXI_139825r 21070 essential YKL165C 844 + ACGGTCATCCTAACAACACA D|282|E silent|GAC>GAT|D|282 H|284|D H|284|Y MCD4 Morphogenesis Checkpoint Dependent 919.0 0 1 0 0 0.515552957247024 P36051 0.9532920122146606 0.9473130106925964 0.9489949941635132 0.0 0.0 0.0 46.319699959544714 45.0 0.0 no 7052 chrXI_139920 21072 essential YKL165C 752 - ACTTGTTGACTTTGTCTATA K|257|N silent|AAG>AAA|K|257 MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 0.4176443940053313 P36051 0.9355990290641784 0.5914023518562317 42.591738936831405 30.0 0.0 no 7053 chrXI_140012r 21074 essential YKL165C 657 + CTACTAGGTTGCGATACTGC L|221|V silent|CTA>TTA|L|221 MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 -0.011350463048725778 P36051 0.9512209892272948 0.0 48.95184756848307 50.0 0.0 no 7054 chrXI_140128 21076 essential YKL165C 544 - GACAAAAGCATCCAGCTCGA V|188|L V|188|I MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 -0.29326723194209503 P36051 0.9539830088615416 0.9574310183525084 0.0 0.0 47.509337316337174 50.0 0.0 no 7055 chrXI_140139r 21077 essential YKL165C 530 + TACGCAATCTTCCATCGAGC T|178|R T|178|M Q|179|E Q|179|* MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 0.2557495161211706 P36051 0.9476869702339172 0.9502379894256592 0.9590039849281312 0.010930894874036312 0.006542934570461512 0.9732339382171632 49.84942631925696 50.0 0.0 no 7056 chrXI_140252r 21078 essential YKL165C 417 + TCTACTCATACTTATTCATT S|140|C S|140|F T|141|S T|141|I MCD4 Morphogenesis Checkpoint Dependent 919.0 0 1 0 0 -0.07906078279568468 P36051 0.945252001285553 0.9294660091400146 0.9491789937019348 0.9472420215606691 0.0 0.0 0.02545770071446896 0.012908405624330044 39.999350107652454 25.0 0.0 no 7057 chrXI_140308 21079 essential YKL165C 364 - TGACTTCCAACCTTTTGTGA K|127|N silent|AAG>AAA|K|127 W|126|C W|126|* MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 0.04225151213372308 P36051 0.9355990290641784 0.8858469724655151 0.04985806345939636 0.0 48.13068965205349 40.0 0.0 no 7058 chrXI_140372r 21083 essential YKL165C 297 + ATGCCAACTGAATCCCGTCC P|101|A P|101|S P|101|R P|101|L MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 -0.1705273382464776 P36051 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.0 0.0 0.0 0.0 54.65771476735392 55.00000000000001 0.0 no 7059 chrXI_140369 21085 essential YKL165C 303 - TGACCAGGACGGGATTCAGT G|107|A G|107|D G|107|R G|107|S MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 -1.3641215372551647 P36051 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.0 0.0 0.0 0.0 52.41942325147477 55.00000000000001 0.0 no 7060 chrXI_140395 21086 essential YKL165C 277 - TCTGGTATGTGATATACCGT R|99|T R|99|K MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 -1.0435820078895093 P36051 0.932735025882721 0.955805003643036 0.0 0.0 47.078463023102806 40.0 0.0 no 7061 chrXI_140433r 21087 essential YKL165C 236 + GGCACCTTTTATTAGATCTT A|80|G A|80|V P|81|A P|81|S MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 -0.1518790675074668 P36051 0.9484469890594482 0.9504740238189696 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 47.05103223506899 35.0 0.0 no 7062 chrXI_140531 21088 essential YKL165C 141 - ATCAAAAACAATCTCTTTGC L|53|F silent|TTG>TTA|L|53 MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 -0.3305250538245403 P36051 0.9587849974632264 0.0 36.02520185168896 30.0 0.0 no 7063 chrXI_140536 21089 essential YKL165C 136 - AAACAATCTCTTTGCAGGAG L|51|F silent|TTG>TTA|L|51 MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 0.006049210412342881 P36051 0.9587849974632264 0.0 41.29803977126039 40.0 0.0 no 7064 chrXI_140576 21091 essential YKL165C 96 - GGGCTCATACCATGAACGAG S|38|T S|38|N M|37|I M|37|I MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 -4.3505099927331665 P36051 0.9512869715690612 0.9536849856376648 0.9553959965705872 0.9553959965705872 0.4478297531604767 0.3082630634307861 0.02061774581670761 0.02061774581670761 49.18270778092375 55.00000000000001 0.0 yes 7065 chrXI_140585r 21092 essential YKL165C 84 + TTCATTTCACCGCTCGTTCA F|29|L silent|TTC>TTT|F|29 MCD4 Morphogenesis Checkpoint Dependent 919.0 0 0 0 0 0.589838965174634 P36051 0.9387490153312684 0.0 52.827901303267936 45.0 0.0 no 7066 chrXI_161615 21094 essential YKL154W 14 + ACTTATTATTGCCTGTTTAT L|6|V L|6|F SRP102 Signal Recognition Particle 244.0 0 0 0 0 0.8476467572110681 P36057 0.9512209892272948 0.9587849974632264 0.6760963797569275 0.5990025401115417 42.90289563128357 25.0 1.0 no 7067 chrXI_161650r 21095 essential YKL154W 52 - TTGCACTGCTATTAGCGCTA silent|GTG>GTC|V|23 silent|GTG>GTA|V|23 V|23|L V|23|M SRP102 Signal Recognition Particle 244.0 0 0 0 0 0.5428040312776676 P36057 0.9539830088615416 0.9587630033493042 1.0 0.2289079576730728 51.22472603479854 45.0 1.0 no 7068 chrXI_161623 21096 essential YKL154W 22 + TTGCCTGTTTATTGGTGATA A|9|G A|9|V silent|GCC>GCG|A|9 silent|GCC>GCT|A|9 SRP102 Signal Recognition Particle 244.0 0 0 0 0 -0.11519250791364455 P36057 0.9484469890594482 0.9504740238189696 0.09411050379276276 0.13969174027442932 47.197685788807185 35.0 1.0 no 7069 chrXI_161680r 21098 essential YKL154W 82 - TTGCTTGATCCCTGTCTTGG K|33|N silent|AAG>AAA|K|33 SRP102 Signal Recognition Particle 244.0 0 0 0 0 -0.07171604267793551 P36057 0.9355990290641784 0.36038294434547424 55.23240670422865 50.0 1.0 no 7070 chrXI_161864r 21103 essential YKL154W 266 - AACGCAACTTGACATGGCCT R|95|P R|95|H L|94|F silent|TTG>TTA|L|94 SRP102 Signal Recognition Particle 244.0 0 0 0 0 0.5625977087239333 P36057 0.9099509716033936 0.9570810198783876 0.9587849974632264 0.07377731055021286 0.3143688142299652 0.0 1.1574219465255735 0.1999599933624268 0.31751200556755066 -0.0376800000667572 5.66500997543335 -0.5933899879455566 2.33335018157959 49.52017022164364 50.0 1.0 no 7071 chrXI_161910 21105 essential YKL154W 309 + ACAAGAGCCAAATTTGTTAA T|104|R T|104|I SRP102 Signal Recognition Particle 244.0 0 0 0 0 0.8036825895403144 P36057 0.9476869702339172 0.9472420215606691 0.139208123087883 0.03451855480670929 -0.09654200077056883 -0.19409599900245667 38.262870876299075 30.0 1.0 no 7072 chrXI_161917r 21106 essential YKL154W 319 - TATCAACCCTTTAACAAATT L|112|F silent|TTG>TTA|L|112 silent|GGG>GGC|G|111 silent|GGG>GGA|G|111 SRP102 Signal Recognition Particle 244.0 0 0 0 0 0.5884855166887661 P36057 0.9587849974632264 0.04969693347811699 2.1928598880767822 7.5709590911865225 37.617759237018156 25.0 1.0 no 7073 chrXI_161975 21107 essential YKL154W 374 + AACAACAACAGCTGAGTTCT T|126|R T|126|I T|127|R T|127|I SRP102 Signal Recognition Particle 244.0 0 0 0 0 0.677996589146854 P36057 0.9476869702339172 0.9472420215606691 0.9476869702339172 0.9472420215606691 0.04109067097306252 0.5683836340904236 0.15767337381839752 0.056091468781232834 0.37715798616409296 0.026871999725699425 -0.5720260143280029 -0.416373997926712 -0.3422800004482269 -0.2452999949455261 -0.17618000507354736 -0.4006600081920624 42.37368874291485 40.0 1.0 no 7074 chrXI_161964r 21108 essential YKL154W 366 - GCTGTTGTTGTTAATTTCTT A|129|P A|129|T SRP102 Signal Recognition Particle 244.0 0 0 0 0 0.6063991318683691 P36057 0.9573720097541808 0.9523990154266356 0.0 0.0 3.87933611869812 1.5923160314559937 44.53405705257933 30.0 1.0 no 7075 chrXI_162124 21111 essential YKL154W 523 + TTCAAAAGGTTATTGAAAGA Q|176|E Q|176|* SRP102 Signal Recognition Particle 244.0 0 1 0 0 0.016035569603979928 P36057 0.9590039849281312 1.0 0.4787819981575012 32.4488502032317 25.0 1.0 no 7076 chrXI_163810 21112 essential YKL152C 556 - GTGCTTAACCAAACCTCTCA K|191|N silent|AAG>AAA|K|191 GPM1 Glycerate PhosphoMutase 247.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.09543819293948974 P00950 0.5708280205726624 0.0037193146999925375 2.921799898147583 48.96707734267784 45.0 0.0 no 7077 chrXI_163883 21117 essential YKL152C 483 - GCAATGACATCTTGCCAGTA A|168|P A|168|T GPM1 Glycerate PhosphoMutase 247.0 0 1 0 0 -0.3826895109309488 P00950 0.7170829772949219 0.8808689713478088 0.12375106662511826 0.31699836254119873 6.731540203094482 0.3161599934101105 9.718159675598145 3.5708599090576167 49.5357760698401 45.0 0.0 no 7078 chrXI_163937 21118 essential YKL152C 429 - TCAGTTTCTGGCAAGACATT E|150|Q E|150|K GPM1 Glycerate PhosphoMutase 247.0 0 0 0 0 -0.6109561850219682 P00950 0.6495220065116882 0.5671039819717407 0.0 0.0 2.646899938583374 4.941199779510498 46.64910915050734 40.0 0.0 no 7079 chrXI_163986r 21120 essential YKL152C 377 + TTCTTCTCCATTCTCTCAAA S|127|C S|127|F S|128|C S|128|F GPM1 Glycerate PhosphoMutase 247.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.4306820221761035 P00950 0.779449999332428 0.7881879806518555 0.7203559875488281 0.7141849994659424 0.017757905647158626 0.015731070190668106 0.016522297635674477 0.015019385144114494 0.8411200046539307 0.6416199803352356 0.3682399988174439 -0.5838000178337097 0.1184599995613098 -0.18775999546051025 0.007780000101774931 -1.0221600532531738 46.69912222820193 35.0 0.0 no 7080 chrXI_164029 21122 essential YKL152C 337 - AACATCGAAGGATCTTCTGT V|119|L V|119|I D|118|H D|118|N GPM1 Glycerate PhosphoMutase 247.0 0 1 0 0 0.3055113578235471 P00950 0.9113069772720336 0.9504910111427308 0.7755270004272461 0.94758802652359 0.05138065293431282 0.7732847332954407 0.009745976887643336 0.12111766636371613 -0.775160014629364 -0.35565999150276184 0.1505800038576126 0.09656000137329103 -0.6823199987411499 -0.42937999963760376 43.423219573409995 40.0 0.0 no 7081 chrXI_164097r 21124 essential YKL152C 266 + TTACGGTGACTTACAAGGTA Y|90|* silent|TAC>TAT|Y|90 GPM1 Glycerate PhosphoMutase 247.0 0 0 0 0 -0.38479153400155136 P00950 43.393890455150604 40.0 0.0 no 7082 chrXI_164172r 21125 essential YKL152C 191 + TGCTAACATTGCTTTGGAAA A|65|G A|65|V N|66|K silent|AAC>AAT|N|66 GPM1 Glycerate PhosphoMutase 247.0 0 0 0 0 -0.7499501721207845 P00950 0.6805559992790222 0.6496400237083435 0.7083600163459778 0.39240908622741705 0.40463945269584656 0.2962507605552673 1.941540002822876 1.7438199520111084 -0.4957000017166138 41.36639866745298 35.0 0.0 no 7083 chrXI_164178r 21126 essential YKL152C 185 + CCAAACTGCTAACATTGCTT Q|63|E Q|63|* T|64|S T|64|I GPM1 Glycerate PhosphoMutase 247.0 0 0 0 0 -0.026012885402484254 P00950 0.9216439723968506 0.7257729768753052 0.615863025188446 0.02665344998240471 0.05682541057467461 0.0022652654442936178 0.1762000024318695 0.4412600100040436 1.627959966659546 44.72327997370979 40.0 0.0 no 7084 chrXI_164257 21127 essential YKL152C 109 - CAACAATTCACCGGCTCTAG L|42|F silent|TTG>TTA|L|42 GPM1 Glycerate PhosphoMutase 247.0 0 1 0 0 -0.2272852032739335 P00950 0.9052219986915588 0.09457619488239287 1.475659966468811 0.6563400030136108 47.31766731154392 50.0 0.0 no 7085 chrXI_164360 21130 essential YKL152C 6 - TGTCTAACTAAAACTAACTT R|8|T R|8|K GPM1 Glycerate PhosphoMutase 247.0 0 1 0 0 -3.284544669394701 P00950 0.6615949869155884 0.8035809993743896 0.0 0.0 0.8960000276565552 0.09911999851465224 33.156989418850735 25.0 0.0 yes 7086 chrXI_174352r 21132 essential YKL145W 142 - ATTCTCAGTTTGCTTTAATT E|53|D silent|GAG>GAA|E|53 E|53|Q E|53|K RPT1 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 467.0 0 1 0 0 -0.08924295398797187 P33299 0.94931298494339 0.956179976463318 0.9475290179252625 0.4277999997138977 -1.7516000270843506 -0.4357999861240387 41.67725360640668 25.0 1.0 no 7087 chrXI_174669 21134 essential YKL145W 456 + GCCAAATTTGTCGTCGGATT silent|GCC>GCG|A|153 silent|GCC>GCT|A|153 A|153|G A|153|V RPT1 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 467.0 0 0 0 0 -0.3621788158382837 P33299 0.9484469890594482 0.9504740238189696 0.605964720249176 0.17238537967205048 48.5719434271511 45.0 1.0 no 7088 chrXI_174808r 21139 essential YKL145W 598 - AACGTCAGGCTTTTCTTCAA V|206|L V|206|I D|205|H D|205|N RPT1 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 467.0 0 0 0 0 0.5257423848698086 P33299 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 0.19164122641086576 0.3210156559944153 0.005520359147340059 0.3647482991218567 -1.011699914932251 -0.8210999965667725 0.4374000132083893 0.1324000060558319 46.760217391472615 40.0 1.0 no 7089 chrXI_174894r 21141 essential YKL145W 684 - AATCTTTCTGGAGATAATAA R|234|T R|234|K RPT1 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 467.0 0 1 0 0 -0.6629497154027673 P33299 0.932735025882721 0.955805003643036 0.16200430691242218 1.0 34.775826601883175 25.0 1.0 no 7090 chrXI_174923 21144 essential YKL145W 710 + TCTTGGTATTGATCCACCAA L|238|V L|238|F RPT1 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 467.0 0 0 0 0 -0.2844828228777983 P33299 0.9512209892272948 0.9587849974632264 0.4648436605930328 0.010669405572116377 48.2825898121659 40.0 1.0 no 7091 chrXI_174939 21145 essential YKL145W 726 + CCAAAGGGTATCTTATTATA P|243|R P|243|L RPT1 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 467.0 0 0 0 0 0.6853079476323496 P33299 0.9432820081710817 0.9430609941482544 0.003348648315295577 0.004424490034580232 39.90241242549485 30.0 1.0 no 7092 chrXI_175044 21149 essential YKL145W 831 + GAGCTAGTGCAAAAATATGT L|279|V silent|CTA>TTA|L|279 RPT1 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 467.0 0 1 0 0 -0.6347905567843892 P33299 0.9512209892272948 0.00802162941545248 -0.6576200127601624 39.01453098323782 35.0 1.0 no 7093 chrXI_175050 21150 essential YKL145W 837 + GTGCAAAAATATGTCGGTGA Q|281|E Q|281|* RPT1 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 467.0 0 1 0 0 -0.18154806374439209 P33299 0.9590039849281312 0.08652444928884506 0.5140999555587769 41.15923539267703 40.0 1.0 no 7094 chrXI_175244r 21154 essential YKL145W 1034 - TCACTTTAATGTTACCACGA V|351|L V|351|M silent|GTG>GTC|V|351 silent|GTG>GTA|V|351 RPT1 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 467.0 0 0 0 0 0.1703447878972959 P33299 0.9539830088615416 0.9587630033493042 0.034433506429195404 0.14442139863967896 43.022317480769864 35.0 1.0 no 7095 chrXI_176095 21155 essential YKL144C 367 - AATCCATGCACTTTCTTCAG W|128|C W|128|* W|128|S W|128|* RPC25 RNA Polymerase C 212.0 0 0 0 0 -3.2235683388637546 P35718 0.0 0.0 3.8017199039459233 5.549499988555908 47.04701162789161 40.0 0.0 yes 7096 chrXI_176128r 21156 essential YKL144C 331 + CACAAAATATGTTATTCGAA Q|112|E Q|112|* RPC25 RNA Polymerase C 212.0 0 0 0 0 0.9106180300902256 P35718 0.7514992356300354 32.930470619194864 25.0 0.0 no 7097 chrXI_176129r 21157 essential YKL144C 330 + CCACAAAATATGTTATTCGA Q|112|E Q|112|* P|111|R P|111|L RPC25 RNA Polymerase C 212.0 0 0 0 0 0.3825464814752184 P35718 0.7514992356300354 0.0 0.0 37.675003629331634 30.0 0.0 no 7098 chrXI_176129 21158 essential YKL144C 333 - CCTTCGAATAACATATTTTG G|118|R G|118|R E|117|Q E|117|K RPC25 RNA Polymerase C 212.0 0 0 0 0 0.13767483433648778 P35718 0.1219702884554863 0.1219702884554863 0.3841769397258759 0.11312603950500487 37.57777277142583 30.0 0.0 no 7099 chrXI_176302 21160 essential YKL144C 160 - CTTCAATTGGCCTTCCTCGA L|59|F silent|TTG>TTA|L|59 RPC25 RNA Polymerase C 212.0 0 0 0 0 0.14035648690119268 P35718 0.011390307918190956 -0.12917999923229218 54.04041621631927 50.0 0.0 no 7100 chrXI_176316r 21162 essential YKL144C 143 + TTACGACTTATTAACCGTCG Y|49|* silent|TAC>TAT|Y|49 D|50|E silent|GAC>GAT|D|50 RPC25 RNA Polymerase C 212.0 0 0 0 0 0.4128734948119897 P35718 0.04734040796756744 42.479017519937365 40.0 0.0 no 7101 chrXI_176354r 21163 essential YKL144C 105 + AACAAGATTATTCCCAATGT N|36|K silent|AAC>AAT|N|36 RPC25 RNA Polymerase C 212.0 0 0 0 0 -0.1253528040533292 P35718 0.0 40.44702458304829 30.0 0.0 no 7102 chrXI_176356 21164 essential YKL144C 106 - GACATTGGGAATAATCTTGT V|42|L V|42|I RPC25 RNA Polymerase C 212.0 0 0 0 0 -0.40840840698765735 P35718 0.33162781596183777 0.42143651843070973 -0.976199984550476 -0.4610199928283691 40.485289488472574 35.0 0.0 no 7103 chrXI_176451r 21170 essential YKL144C 8 + CCTTTCAAAAATCGCTGACT L|4|V L|4|F S|5|* S|5|L RPC25 RNA Polymerase C 212.0 0 1 0 0 0.21531501122644006 P35718 0.0 0.0 0.14151714742183685 1.5160399675369265 -0.44242000579833984 42.95253117069802 40.0 0.0 no 7104 chrXI_179740 21174 essential YKL141W 73 + CAGCTGCCTTGAGCTCCTCG A|26|G A|26|V A|27|G A|27|V SDH3 Succinate DeHydrogenase 198.0 0 0 0 0 0.8917372885577582 P33421 0.9484469890594482 0.9504740238189696 0.9484469890594482 0.9504740238189696 0.4730343222618103 0.5941610932350159 61.22807394618371 65.0 1.0 no 7105 chrXI_179824r 21178 essential YKL141W 160 - CGCTTTGGTGTTCATTTCAC A|60|P A|60|T SDH3 Succinate DeHydrogenase 198.0 0 0 0 0 0.2264144366342373 P33421 0.9573720097541808 0.9523990154266356 0.09340933710336684 1.0 49.923830542338116 45.0 1.0 no 7106 chrXI_179839r 21179 essential YKL141W 175 - TTCTTCAGCAATTGCCGCTT E|65|Q E|65|K E|64|Q E|64|K SDH3 Succinate DeHydrogenase 198.0 0 0 0 0 1.1693772889253318 P33421 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.612260103225708 0.7140361666679382 0.09127718955278397 0.08120807260274887 52.94243564015983 45.0 1.0 no 7107 chrXI_179945 21181 essential YKL141W 278 + TTCTCTTCACCGTATTTCGT S|94|C S|94|F L|95|V L|95|F SDH3 Succinate DeHydrogenase 198.0 0 0 0 0 -0.7983502961929225 P33421 0.945252001285553 0.9294660091400146 0.9512209892272948 0.9587849974632264 0.01962952502071857 0.007751899771392345 0.4568731188774109 0.15929652750492096 50.530115722125466 40.0 1.0 no 7108 chrXI_179922r 21182 essential YKL141W 258 - GACAGGTACCAAGTTAATTG silent|CTG>CTC|L|92 silent|CTG>CTA|L|92 SDH3 Succinate DeHydrogenase 198.0 0 0 0 0 0.5684764934209678 P33421 41.769632636852066 40.0 1.0 no 7109 chrXI_179954 21183 essential YKL141W 287 + CCGTATTTCGTTGGTGCTTA R|97|G R|97|C SDH3 Succinate DeHydrogenase 198.0 0 0 0 0 0.32330679491848624 P33421 0.8994590044021606 0.8926740288734436 0.0 0.0 51.83725745104152 45.0 1.0 no 7110 chrXI_179954r 21184 essential YKL141W 290 - CCATAAGCACCAACGAAATA M|103|I M|103|I SDH3 Succinate DeHydrogenase 198.0 0 0 0 0 -0.4204925104002073 P33421 0.9553959965705872 0.9553959965705872 0.16896049678325653 0.16896049678325653 41.28569973135791 40.0 1.0 no 7111 chrXI_179988 21186 essential YKL141W 321 + TACTTGTTTACTATACTCTT Y|108|* silent|TAC>TAT|Y|108 SDH3 Succinate DeHydrogenase 198.0 0 0 0 0 0.3707345069637072 P33421 39.872141376427976 25.0 1.0 no 7112 chrXI_180043r 21190 essential YKL141W 379 - GTACCAATTAGAAACCTTTT W|132|C W|132|* W|132|S W|132|* SDH3 Succinate DeHydrogenase 198.0 0 0 0 0 0.8655160632373042 P33421 0.8858469724655151 0.8858469724655151 0.053146641701459885 0.1187226101756096 40.37378105609719 30.0 1.0 no 7113 chrXI_183110 21193 high_effect YKL139W 152 + GGACAATATATCTTCTCATA D|52|E silent|GAC>GAT|D|52 CTK1 Carboxy-Terminal domain Kinase 528.0 0 0 0 0 -0.3963116617409965 Q03957 1.0 39.43517892094047 30.0 1.0 no 7114 chrXI_183146r 21194 high_effect YKL139W 191 - GACTTTTCGTGTGGCCTGGT S|70|T S|70|N CTK1 Carboxy-Terminal domain Kinase 528.0 0 0 0 0 -0.551362084968124 Q03957 0.9042911529541016 0.5905023217201233 57.864416295415246 55.00000000000001 1.0 no 7115 chrXI_183308 21197 high_effect YKL139W 350 + ATTCCTGTCTCATTTGCCAA F|118|L silent|TTC>TTT|F|118 L|119|V silent|CTG>TTG|L|119 CTK1 Carboxy-Terminal domain Kinase 528.0 0 0 0 0 -0.07938330776526673 Q03957 0.7097072005271912 0.5252931714057922 51.65719996143309 40.0 1.0 no 7116 chrXI_183334r 21199 high_effect YKL139W 379 - TCTTGATTTCTCAACAGATT R|133|T R|133|K CTK1 Carboxy-Terminal domain Kinase 528.0 0 0 0 0 0.9245879149070546 Q03957 0.9924970865249634 0.7598149180412292 40.736468002927715 30.0 1.0 no 7117 chrXI_183408 21200 high_effect YKL139W 450 + TCAAAATACTATAACCACAA S|151|* S|151|L CTK1 Carboxy-Terminal domain Kinase 528.0 0 0 0 0 -0.5254302500388095 Q03957 0.32381686568260193 33.424433597687376 25.0 1.0 no 7118 chrXI_183422r 21203 high_effect YKL139W 467 - ACCGCCCTTCCTGGCCTTTG R|162|P R|162|Q silent|CGG>CGC|R|162 silent|CGG>CGA|R|162 CTK1 Carboxy-Terminal domain Kinase 528.0 0 0 0 0 -0.11430604683522914 Q03957 0.25428256392478943 0.7391576766967773 65.40682796467735 65.0 1.0 no 7119 chrXI_183469 21206 high_effect YKL139W 511 + TTTCGGTTCTAACGCAGCAA S|172|W S|172|L CTK1 Carboxy-Terminal domain Kinase 528.0 0 0 0 0 1.3127401884439556 Q03957 0.18386748433113095 0.6861128807067871 47.84869595089521 45.0 1.0 no 7120 chrXI_183628r 21207 high_effect YKL139W 673 - AATCTCTCGTATAGAGGTTA E|230|D silent|GAG>GAA|E|230 E|230|Q E|230|K CTK1 Carboxy-Terminal domain Kinase 528.0 0 0 0 0 0.24893452374030445 Q03957 0.0 0.0 0.0 42.8004063783814 35.0 1.0 no 7121 chrXI_183813 21210 high_effect YKL139W 855 + CTCTTCAAACAATTGCTATT silent|CTC>CTG|L|286 silent|CTC>CTT|L|286 F|287|L silent|TTC>TTT|F|287 CTK1 Carboxy-Terminal domain Kinase 528.0 0 0 0 0 0.1869877614022476 Q03957 0.318628191947937 39.20464336507894 30.0 1.0 no 7122 chrXI_183887 21212 high_effect YKL139W 929 + AAACATCTTAATCGATAACC N|311|K silent|AAC>AAT|N|311 I|312|M silent|ATC>ATT|I|312 CTK1 Carboxy-Terminal domain Kinase 528.0 0 1 0 0 0.5398318305321577 Q03957 0.0 0.01515934057533741 35.645231370276576 30.0 1.0 no 7123 chrXI_205786r 21214 high_effect YKL126W 82 - CTGCTGTTCTTCCTTTTTAG Q|33|H silent|CAG>CAA|Q|33 YPK1 Yeast Protein Kinase 680.0 0 0 0 0 0.3035186936484722 P12688 0.9570760130882264 49.96301023107583 40.0 1.0 no 7124 chrXI_205805 21215 high_effect YKL126W 98 + GCAGAATAATCAAGCAACTG Q|34|E Q|34|* YPK1 Yeast Protein Kinase 680.0 0 0 0 0 0.3027328628256213 P12688 0.9590039849281312 38.79585352505938 40.0 1.0 no 7125 chrXI_205846 21216 high_effect YKL126W 139 + TTACTCGTTCATCTTTAGAC T|48|S T|48|I R|49|G R|49|C YPK1 Yeast Protein Kinase 680.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.33561270520295344 P12688 0.9491789937019348 0.9472420215606691 0.8994590044021606 0.8926740288734436 42.88859420630826 35.0 1.0 no 7126 chrXI_205850 21219 high_effect YKL126W 143 + TCGTTCATCTTTAGACAGGA R|49|G R|49|C S|50|* S|50|L YPK1 Yeast Protein Kinase 680.0 0 1 0 0 -0.2306248209405929 P12688 0.8994590044021606 0.8926740288734436 0.9298099875450134 46.06179837066628 40.0 1.0 no 7127 chrXI_205905r 21221 high_effect YKL126W 201 - GCATCGTATGAAACACGAAC A|74|P A|74|T D|73|H D|73|N YPK1 Yeast Protein Kinase 680.0 0 1 0 0 -0.2518970167023367 P12688 0.9573720097541808 0.9523990154266356 0.9486550092697144 0.956179976463318 0.2583405673503876 0.264297753572464 0.10869308561086656 0.5844889283180237 40.593504597705994 45.0 1.0 no 7128 chrXI_205941 21222 high_effect YKL126W 234 + TCTACTGTACGAGATTCAAA S|79|C S|79|F T|80|S T|80|I YPK1 Yeast Protein Kinase 680.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.21556448144328128 P12688 0.945252001285553 0.9294660091400146 0.9491789937019348 0.9472420215606691 0.044832758605480194 0.1696668565273285 0.4844105839729309 0.06959585845470427 39.51464019028742 35.0 1.0 no 7129 chrXI_206008 21223 high_effect YKL126W 301 + CAGCAAATATTGGTTCTACA A|102|G A|102|V YPK1 Yeast Protein Kinase 680.0 0 0 0 0 0.4100233243789198 P12688 0.9484469890594482 0.9504740238189696 0.4206473827362061 0.3032412827014923 41.43858362926471 35.0 1.0 no 7130 chrXI_206044r 21225 high_effect YKL126W 340 - CATCATTCCTGAACTTGAGG M|119|I M|119|I YPK1 Yeast Protein Kinase 680.0 0 0 0 0 0.4525603503892438 P12688 0.9553959965705872 0.9553959965705872 0.2905290722846985 0.2905290722846985 45.59467637341089 45.0 1.0 no 7131 chrXI_206234r 21230 high_effect YKL126W 530 - AATCTTCATCAGCTGGACCT D|183|H D|183|N E|182|Q E|182|K YPK1 Yeast Protein Kinase 680.0 0 0 0 0 0.13812058834192822 P12688 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.12058639526367188 0.5446735620498657 0.4793943166732788 0.6958444714546204 50.73115927226343 45.0 1.0 no 7132 chrXI_206290 21232 high_effect YKL126W 583 + CATCTACTATCATGTTACCA S|196|C S|196|F T|197|S T|197|I YPK1 Yeast Protein Kinase 680.0 0 0 0 0 0.5478054257037792 P12688 0.945252001285553 0.9294660091400146 0.9491789937019348 0.9472420215606691 0.02044055238366127 0.026758531108498573 0.8968034982681274 0.4563176929950714 44.61719088871666 35.0 1.0 no 7133 chrXI_206329r 21234 high_effect YKL126W 625 - TTCAATGGTGAAATATAGTA E|215|Q E|215|K YPK1 Yeast Protein Kinase 680.0 0 0 0 0 0.6327084201699509 P12688 0.956179976463318 0.9475290179252625 0.019238125532865524 0.014912812039256098 34.43556606436118 25.0 1.0 no 7134 chrXI_206488 21235 high_effect YKL126W 781 + TTCTTTTGCCCTCGAAGACA L|262|V L|262|F YPK1 Yeast Protein Kinase 680.0 0 0 0 0 1.2293344262209418 P12688 0.9512209892272948 0.9587849974632264 0.611212432384491 0.5866872668266296 50.91070333747427 45.0 1.0 no 7135 chrXI_206496r 21237 high_effect YKL126W 792 - TCCTGTTGCCATGTCTTCGA Q|270|H silent|CAG>CAA|Q|270 E|271|Q E|271|K YPK1 Yeast Protein Kinase 680.0 0 0 0 0 0.0935122290671018 P12688 0.9570760130882264 0.956179976463318 0.9475290179252625 0.0573691800236702 0.09992286562919617 0.33644068241119385 56.702449352421134 50.0 1.0 no 7136 chrXI_206813 21244 high_effect YKL126W 1106 + ACAAAAAGTATACGCTTTGA Q|370|E Q|370|* YPK1 Yeast Protein Kinase 680.0 0 0 0 0 0.8601731858992443 P12688 0.9590039849281312 0.3916752338409424 36.1165896975146 30.0 1.0 no 7137 chrXI_206007 21245 high_effect YKL126W 300 + ACAGCAAATATTGGTTCTAC T|101|R T|101|I A|102|G A|102|V YPK1 Yeast Protein Kinase 680.0 0 0 0 0 0.22042357437395288 P12688 0.9476869702339172 0.9472420215606691 0.9484469890594482 0.9504740238189696 0.5939540863037109 0.1876649409532547 0.4206473827362061 0.3032412827014923 40.530079307846506 35.0 1.0 no 7138 chrXI_206896r 21246 high_effect YKL126W 1192 - ACAATCAACACGTGCTAGAA C|404|S C|404|Y D|403|H D|403|N YPK1 Yeast Protein Kinase 680.0 0 0 0 0 1.176823086298305 P12688 0.9421560168266296 0.9290120005607604 0.9486550092697144 0.956179976463318 0.2899378836154938 0.05248184502124786 0.027014009654521942 1.0 41.13304533434722 40.0 1.0 no 7139 chrXI_207153 21248 high_effect YKL126W 1446 + CACATTGCCCTTTGTGATTT H|483|Q silent|CAC>CAT|H|483 YPK1 Yeast Protein Kinase 680.0 0 0 0 0 0.314880549712758 P12688 0.9588389992713928 0.0 50.399339623875726 40.0 1.0 no 7140 chrXI_207058r 21249 high_effect YKL126W 1354 - TAGCGCACATAACAATTCTG silent|GCG>GCC|A|457 silent|GCG>GCA|A|457 A|457|P A|457|T YPK1 Yeast Protein Kinase 680.0 0 0 0 1 -0.2062690621307368 P12688 0.9573720097541808 0.9523990154266356 0.0 0.0 41.74404601772586 40.0 1.0 no 7141 chrXI_207154 21250 high_effect YKL126W 1447 + ACATTGCCCTTTGTGATTTC H|483|Q silent|CAC>CAT|H|483 A|485|G A|485|V YPK1 Yeast Protein Kinase 680.0 0 0 0 0 0.9486521877232504 P12688 0.9588389992713928 0.9484469890594482 0.9504740238189696 0.0 0.0218167956918478 0.0723084807395935 50.241016428367175 40.0 1.0 no 7142 chrXI_207161r 21252 high_effect YKL126W 1457 - TGCATAGCCCGAAATCACAA C|492|S C|492|Y YPK1 Yeast Protein Kinase 680.0 0 0 0 0 0.07818161252151254 P12688 0.9421560168266296 0.9290120005607604 0.0 0.0 46.68053628383064 45.0 1.0 no 7143 chrXI_207176 21253 high_effect YKL126W 1469 + GCTATGCAAATTGAATATGA L|491|V silent|CTA>TTA|L|491 C|492|W silent|TGC>TGT|C|492 YPK1 Yeast Protein Kinase 680.0 0 0 0 0 -0.09621533141909676 P12688 0.9512209892272948 0.9286419749259948 0.0 0.0 37.154155757021435 30.0 1.0 no 7144 chrXI_208395r 21260 essential YKL125W 151 - TTTCACGAACCTGCTATACA silent|GTG>GTC|V|56 silent|GTG>GTA|V|56 V|56|L V|56|M RRN3 Regulation of RNA polymerase I 627.0 0 0 0 0 -0.7893657553599243 P36070 0.056105829775333405 0.010571581311523914 -1.5667999982833862 -0.038600001484155655 45.57751563261155 40.0 1.0 no 7145 chrXI_208422r 21261 essential YKL125W 178 - ATTCTTATCCAGATCATCTA K|65|N silent|AAG>AAA|K|65 RRN3 Regulation of RNA polymerase I 627.0 0 0 0 0 -0.4960547039264399 P36070 0.3313390612602234 -0.14579999446868894 43.89971926665595 30.0 1.0 no 7146 chrXI_208487r 21263 essential YKL125W 243 - ATTCTTTCAGGATTCTTGCT R|87|T R|87|K RRN3 Regulation of RNA polymerase I 627.0 0 0 0 0 -0.005541088229651908 P36070 0.23967914283275604 0.18837232887744906 1.2247999906539917 0.17640000581741333 47.82386370001666 35.0 1.0 no 7147 chrXI_208559 21266 essential YKL125W 312 + AACAGGATAGAATCCTCCAG N|105|K silent|AAC>AAT|N|105 RRN3 Regulation of RNA polymerase I 627.0 0 0 0 0 0.10251846991584544 P36070 0.17454810440540314 -0.4986000061035156 45.15006595503036 45.0 1.0 no 7148 chrXI_208557 21267 essential YKL125W 310 + TCAACAGGATAGAATCCTCC I|104|M silent|ATC>ATT|I|104 N|105|K silent|AAC>AAT|N|105 RRN3 Regulation of RNA polymerase I 627.0 0 0 0 0 0.5238454402218518 P36070 0.012700191698968409 0.17454810440540314 -0.31439998745918274 -0.4986000061035156 46.06161034324202 45.0 1.0 no 7149 chrXI_208677 21268 essential YKL125W 430 + GCTCGAGTATACCCAAATGG S|145|W S|145|L C|144|W silent|TGC>TGT|C|144 RRN3 Regulation of RNA polymerase I 627.0 0 0 0 0 -2.4693574918190464 P36070 0.001152522279880941 0.007321758195757866 0.004060087259858847 0.04600000008940697 -0.15479999780654907 25.48151969909668 48.1191900779781 50.0 1.0 yes 7150 chrXI_208797r 21270 essential YKL125W 553 - ATCTATGAATCCCATCGAGG D|191|H D|191|N RRN3 Regulation of RNA polymerase I 627.0 0 0 0 0 -1.1614439779595374 P36070 0.13902625441551208 0.31251880526542664 -0.03759999945759773 0.19820000231266025 46.892123407683364 45.0 1.0 no 7151 chrXI_208796r 21271 essential YKL125W 552 - TCTATGAATCCCATCGAGGA D|191|H D|191|N RRN3 Regulation of RNA polymerase I 627.0 0 0 0 0 -1.1955291889348314 P36070 0.13902625441551208 0.31251880526542664 -0.03759999945759773 0.19820000231266025 48.05476488150583 45.0 1.0 no 7152 chrXI_209051 21273 essential YKL125W 804 + GACGATTTAGATGATGATTC D|269|E silent|GAC>GAT|D|269 RRN3 Regulation of RNA polymerase I 627.0 0 0 0 0 0.2550251953204471 P36070 1.0 38.26518536077271 35.0 1.0 no 7153 chrXI_209130r 21274 essential YKL125W 886 - ACTATCACTTTGACTACCGT S|302|T S|302|N D|301|H D|301|N RRN3 Regulation of RNA polymerase I 627.0 0 0 0 0 0.09690867244430293 P36070 0.5753952264785767 0.4728125035762787 0.05899649485945701 0.5732547640800476 46.95600201991114 40.0 1.0 no 7154 chrXI_209140 21275 essential YKL125W 893 + TCAAAGTGATAGTGAAGATA Q|299|E Q|299|* RRN3 Regulation of RNA polymerase I 627.0 0 0 0 0 -0.2512084086547684 P36070 1.0 34.735228550342754 30.0 1.0 no 7155 chrXI_209291r 21278 essential YKL125W 1047 - TCACCGCTTTCTAAACTCTC G|355|A G|355|D E|356|Q E|356|K RRN3 Regulation of RNA polymerase I 627.0 0 0 0 0 0.5178107632745381 P36070 0.2853250503540039 0.5287429094314575 0.4219338297843933 0.7620457410812378 3.550100088119507 5.3646202087402335 0.6941999793052673 1.4501999616622925 48.241094369425404 45.0 1.0 no 7156 chrXI_209472r 21282 essential YKL125W 1228 - CTTCTCTGCTGCTTCGTTGA E|415|D silent|GAG>GAA|E|415 E|415|Q E|415|K RRN3 Regulation of RNA polymerase I 627.0 0 0 0 0 -0.1460122937318954 P36070 0.2629193961620331 0.06780495494604111 0.05974642559885979 1.138399958610535 1.2979999780654907 1.6075999736785889 54.89685960991909 50.0 1.0 no 7157 chrXI_209550r 21283 essential YKL125W 1306 - AACGAAAATAATTTGAGTTC V|442|L V|442|I RRN3 Regulation of RNA polymerase I 627.0 0 0 0 0 0.2621288986348119 P36070 0.07213268429040909 0.5313859581947327 0.5216000080108643 -0.2044000029563904 31.01857654643396 25.0 1.0 no 7158 chrXI_209571 21285 essential YKL125W 1324 + TTGCAAGCTATTTAACGTCC A|443|G A|443|V RRN3 Regulation of RNA polymerase I 627.0 0 0 0 0 0.928646022566586 P36070 0.007665949407964946 1.0 2.062599897384644 -1.5556000471115112 45.347469692837755 40.0 1.0 no 7159 chrXI_212630 21286 essential YKL122C 349 - GACATCTGTGTTGACAATTA V|123|L V|123|I D|122|H D|122|N SRP21 Signal Recognition Particle 167.0 0 1 0 0 0.5186502122905542 P32342 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 0.22489021718502045 0.6862378120422363 0.02179840393364429 0.05909324437379838 41.36804039893383 35.0 0.0 no 7160 chrXI_212633 21287 essential YKL122C 346 - ATCTGTGTTGACAATTAAGG D|122|H D|122|N SRP21 Signal Recognition Particle 167.0 0 1 0 0 -0.12525712932176086 P32342 0.9486550092697144 0.956179976463318 0.02179840393364429 0.05909324437379838 39.3595016605031 35.0 0.0 no 7161 chrXI_212653 21288 essential YKL122C 326 - TGGCTAAACCAACAATGTCT A|115|P A|115|T SRP21 Signal Recognition Particle 167.0 0 0 0 0 -1.3691503005798815 P32342 0.9573720097541808 0.9523990154266356 0.09945792704820633 0.3520723879337311 43.23867958861688 40.0 0.0 no 7162 chrXI_212784r 21289 essential YKL122C 192 + TCAAGATTACTTAGTGCATT S|65|* S|65|L SRP21 Signal Recognition Particle 167.0 0 0 0 0 0.4662765908575499 P32342 0.9298099875450134 0.0 -0.7680000066757202 40.60848289311451 30.0 0.0 no 7163 chrXI_212852 21290 essential YKL122C 127 - ATGCGAGTTATGAGTTCTAA silent|TCG>TCC|S|48 silent|TCG>TCA|S|48 SRP21 Signal Recognition Particle 167.0 0 0 0 0 0.3833252112666182 P32342 42.33040076978415 35.0 0.0 no 7164 chrXI_212963 21292 essential YKL122C 16 - GTTCGTGATGTAGTTGTCAA silent|ACG>ACC|T|11 silent|ACG>ACA|T|11 SRP21 Signal Recognition Particle 167.0 0 0 0 0 0.5090679496989177 P32342 46.16215119000481 40.0 0.0 no 7165 chrXI_218826 21296 high_effect YKL119C 372 - ATCTGTTTATTAATTTGTGA Q|130|H silent|CAG>CAA|Q|130 VPH2 Vacuolar pH 215.0 0 0 0 0 1.0182184734319095 P32341 0.009452853351831436 36.60513435943477 20.0 0.0 no 7166 chrXI_223608 21300 high_effect YKL114C 828 - TAGCCTTCATCATTTTCGTA G|282|A G|282|D G|282|R G|282|S APN1 APurinic/apyrimidinic eNdonuclease 367.0 0 0 0 0 0.3889180911601279 P22936 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.5935570001602173 0.20750518143177032 0.2396046966314316 0.6270262598991394 47.9777231458595 35.0 0.0 no 7167 chrXI_223611r 21301 high_effect YKL114C 822 + ACTCCATACGAAAATGATGA P|276|A P|276|S T|275|S T|275|I APN1 APurinic/apyrimidinic eNdonuclease 367.0 0 1 0 0 0.8073361863793102 P22936 0.9562489986419678 0.9498909711837769 0.9491789937019348 0.9472420215606691 0.0 0.0 0.0 0.0 38.562945265845606 35.0 0.0 no 7168 chrXI_223636r 21302 high_effect YKL114C 797 + GCAGGGTATCCCTATTGTCT Q|267|E Q|267|* APN1 APurinic/apyrimidinic eNdonuclease 367.0 0 0 0 0 -1.1187561455947472 P22936 0.9590039849281312 1.0 57.31617328861989 50.0 0.0 no 7169 chrXI_223707r 21307 high_effect YKL114C 726 + TTGCATGAACGCTTGGGTCA H|244|D H|244|Y APN1 APurinic/apyrimidinic eNdonuclease 367.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.5253633880358719 P22936 0.9473130106925964 0.9489949941635132 0.0 0.0 50.97974403299474 50.0 0.0 no 7170 chrXI_224067r 21310 high_effect YKL114C 366 + CATCCAGGTTCTACTTTGAA P|124|A P|124|S P|124|R P|124|L APN1 APurinic/apyrimidinic eNdonuclease 367.0 0 1 0 0 0.18488190705206148 P22936 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.0 0.0 0.0 0.0 46.67856934683442 40.0 0.0 no 7171 chrXI_224182 21313 high_effect YKL114C 254 - TAGCCAAATTAATAAAGTAT A|91|P A|91|T L|90|F silent|TTG>TTA|L|90 APN1 APurinic/apyrimidinic eNdonuclease 367.0 0 0 0 0 0.5180003359942041 P22936 0.9573720097541808 0.9523990154266356 0.9587849974632264 0.00759437493979931 0.005222943611443043 0.008703413419425488 7.784599781036378 7.01140022277832 32.308504190829986 20.0 0.0 no 7172 chrXI_224221r 21316 high_effect YKL114C 212 + TTACAATTATAACCCATTGA Y|72|* silent|TAC>TAT|Y|72 APN1 APurinic/apyrimidinic eNdonuclease 367.0 0 0 0 0 0.09964177316136803 P22936 38.26355997391272 25.0 0.0 no 7173 chrXI_224403r 21321 high_effect YKL114C 30 + GCTGTCTCGAAATACAAATT A|11|G A|11|V silent|GTC>GTG|V|12 silent|GTC>GTT|V|12 APN1 APurinic/apyrimidinic eNdonuclease 367.0 0 0 0 0 0.20157879051844527 P22936 0.9484469890594482 0.9504740238189696 0.3839343190193176 0.3276431858539581 39.23350141232544 35.0 0.0 no 7174 chrXI_226608r 21324 essential YKL112W 41 - CCAGGTCTTTATTAATTATA silent|CTG>CTC|L|20 silent|CTG>CTA|L|20 D|19|H D|19|N ABF1 ARS-Binding Factor 1 731.0 0 0 0 1 -0.1785797068886203 P14164 0.9486550092697144 0.956179976463318 0.20304447412490845 0.7687315940856934 39.396895444014376 25.0 1.0 no 7175 chrXI_226647 21325 essential YKL112W 77 + AGGCAAAAAATTTCCCACCT silent|GGC>GGG|G|27 silent|GGC>GGT|G|27 ABF1 ARS-Binding Factor 1 731.0 0 0 0 0 -0.6377135357823014 P14164 45.51365240512718 40.0 1.0 no 7176 chrXI_226661r 21327 essential YKL112W 94 - ATCATACCAAGCACCCAAGG D|38|H D|38|N W|36|C W|36|* ABF1 ARS-Binding Factor 1 731.0 0 0 0 0 -1.6273841405800906 P14164 0.9486550092697144 0.956179976463318 0.8858469724655151 0.06439657509326935 1.0 0.0 50.00802360854931 50.0 1.0 no 7177 chrXI_226664r 21329 essential YKL112W 97 - TACATCATACCAAGCACCCA V|39|L V|39|I D|38|H D|38|N ABF1 ARS-Binding Factor 1 731.0 0 0 0 0 -4.426192804562408 P14164 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 0.15042340755462644 0.21014538407325745 0.06439657509326935 1.0 50.32261302073478 45.0 1.0 yes 7178 chrXI_226717r 21330 essential YKL112W 150 - TGCGAATTCTTTAAAATAAT silent|TCG>TCC|S|56 silent|TCG>TCA|S|56 ABF1 ARS-Binding Factor 1 731.0 0 0 0 0 0.3706726478494964 P14164 31.873529671350237 20.0 1.0 no 7179 chrXI_226783r 21331 essential YKL112W 216 - TAGCTTAGCAAGACTTTAAA S|78|T S|78|N ABF1 ARS-Binding Factor 1 731.0 0 0 0 0 1.1071676678478717 P14164 0.9512869715690612 0.9536849856376648 0.0 0.0 38.009722356045415 30.0 1.0 no 7180 chrXI_226896 21333 essential YKL112W 326 + TAGCAACAACATGAACAACG S|110|R silent|AGC>AGT|S|110 N|111|K silent|AAC>AAT|N|111 ABF1 ARS-Binding Factor 1 731.0 0 0 0 0 0.5784828207186891 P14164 0.9417110085487366 0.9439849853515624 0.5478141307830809 0.6212011575698853 36.93958912344544 40.0 1.0 no 7181 chrXI_227092 21339 essential YKL112W 522 + AACAACATTTTTAAACAGCA N|175|K silent|AAC>AAT|N|175 N|176|K silent|AAC>AAT|N|176 ABF1 ARS-Binding Factor 1 731.0 0 0 0 0 0.3166557568564222 P14164 0.9439849853515624 0.9439849853515624 34.84382346741495 25.0 1.0 no 7182 chrXI_227194r 21343 essential YKL112W 627 - CCGCTGTCATTACCATGAGT S|215|T S|215|N G|216|R G|216|S ABF1 ARS-Binding Factor 1 731.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.6810604786058754 P14164 0.9512869715690612 0.9536849856376648 0.941340982913971 0.951104998588562 0.4757657051086426 0.5372418761253357 0.4724961221218109 0.7308446168899536 53.53565034833115 50.0 1.0 no 7183 chrXI_227223r 21346 essential YKL112W 656 - CGTCATCCTCCTCGTTGTGA D|225|H D|225|N D|224|H D|224|N ABF1 ARS-Binding Factor 1 731.0 0 0 0 0 0.6600108850774349 P14164 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.0693686380982399 0.2378422319889069 0.12525053322315216 0.47684046626091 57.34873121572338 55.00000000000001 1.0 no 7184 chrXI_227312r 21347 essential YKL112W 745 - ATCTACATTTGCGACGGCAT D|255|H D|255|N V|254|L V|254|I ABF1 ARS-Binding Factor 1 731.0 0 1 0 0 -0.5554150375827377 P14164 0.9486550092697144 0.956179976463318 0.9539830088615416 0.9574310183525084 0.17914171516895294 0.5369064807891846 0.2547452449798584 0.2545098066329956 48.64136120227005 45.0 1.0 no 7185 chrXI_227443 21348 essential YKL112W 873 + AACAACAATGTCGGTAGCCA N|292|K silent|AAC>AAT|N|292 N|293|K silent|AAC>AAT|N|293 ABF1 ARS-Binding Factor 1 731.0 0 0 0 0 1.072157169602203 P14164 0.9439849853515624 0.9439849853515624 1.0 0.03187427297234535 46.03110868029636 45.0 1.0 no 7186 chrXI_227527 21352 essential YKL112W 957 + TCTGCTACCGATGATATACC S|320|C S|320|F A|321|G A|321|V ABF1 ARS-Binding Factor 1 731.0 0 0 0 0 -3.356807773862284 P14164 0.945252001285553 0.9294660091400146 0.9484469890594482 0.9504740238189696 0.057047359645366676 0.05620672926306725 0.500567615032196 0.18651257455348969 47.8998154781429 45.0 1.0 yes 7187 chrXI_227575r 21354 essential YKL112W 1008 - TCTAGTGGGTGACTATGATA E|343|Q E|343|K ABF1 ARS-Binding Factor 1 731.0 0 0 0 0 -4.9227879487226245 P14164 0.956179976463318 0.9475290179252625 0.13626191020011902 0.02512261085212231 44.96175161945092 40.0 1.0 yes 7188 chrXI_227758 21357 essential YKL112W 1188 + GACATTTTAATGCAAAGATA D|397|E silent|GAC>GAT|D|397 ABF1 ARS-Binding Factor 1 731.0 0 0 0 0 0.17108779154346446 P14164 0.9532920122146606 0.4448630213737488 34.18425584450438 25.0 1.0 no 7189 chrXI_227970 21359 essential YKL112W 1400 + TATCGACTACGCCAAACATC I|468|M silent|ATC>ATT|I|468 D|469|E silent|GAC>GAT|D|469 ABF1 ARS-Binding Factor 1 731.0 0 1 0 0 0.8113537419544024 P14164 0.9598389863967896 0.9532920122146606 0.12350979447364807 1.0 44.04978770817161 45.0 1.0 no 7190 chrXI_227981r 21360 essential YKL112W 1414 - ACTTGATATTTCCTGATGTT S|478|T S|478|N ABF1 ARS-Binding Factor 1 731.0 0 0 0 0 -0.18429158848561164 P14164 0.9512869715690612 0.9536849856376648 0.5845476984977722 0.4982672333717346 43.51030029937693 30.0 1.0 no 7191 chrXI_228092r 21362 essential YKL112W 1525 - CACACTTTCCATTAAATTTG V|515|L V|515|M S|514|T S|514|N ABF1 ARS-Binding Factor 1 731.0 0 1 0 0 -0.4434833690322307 P14164 0.9539830088615416 0.9587630033493042 0.9512869715690612 0.9536849856376648 0.5148046016693115 0.18689994513988492 0.6267771124839783 0.5694728493690491 38.73124347988176 30.0 1.0 no 7192 chrXI_228135r 21363 essential YKL112W 1568 - GCATCTTCTTGGGTTGATAC M|529|I M|529|I K|528|N silent|AAG>AAA|K|528 ABF1 ARS-Binding Factor 1 731.0 0 1 0 0 0.4553447836653356 P14164 0.9553959965705872 0.9553959965705872 0.9355990290641784 0.436501145362854 0.436501145362854 0.5125225186347961 49.31825056137041 45.0 1.0 no 7193 chrXI_228157r 21365 essential YKL112W 1590 - TTGCTCCATTTATTGACGCT S|536|T S|536|N W|535|C W|535|* ABF1 ARS-Binding Factor 1 731.0 0 1 0 0 -0.07010332696155025 P14164 0.9512869715690612 0.9536849856376648 0.8858469724655151 0.6306228637695312 0.6586820483207703 0.13314442336559296 49.57086040993477 40.0 1.0 no 7194 chrXI_228192 21366 essential YKL112W 1622 + AACTCATTCAGACGTGTCCA T|542|S T|542|I H|543|D H|543|Y ABF1 ARS-Binding Factor 1 731.0 0 0 0 0 -0.5207326802275646 P14164 0.9491789937019348 0.9472420215606691 0.9473130106925964 0.9489949941635132 0.7376797199249268 0.20295709371566767 0.4146463871002197 1.0 48.957692257991646 45.0 1.0 no 7195 chrXI_234507r 21368 essential YKL108W 84 - CTCTTGATGTCATCCCTTGT K|34|N silent|AAG>AAA|K|34 0 1 0 0 -1.222099516007538 P34252 0.02525858581066132 53.88171495034601 45.0 1.0 no 7196 chrXI_234674 21371 essential YKL108W 248 + TACTCCCCAAGTTTACGGTA T|84|S T|84|I P|85|A P|85|S 1 Series([], Name: modification, dtype: object) 0 0 0 -1.4489620760209283 P34252 0.0 0.0 0.0 0.0 51.559240622647906 45.0 1.0 no 7197 chrXI_234678r 21373 essential YKL108W 255 - ATCGCCTTACCGTAAACTTG silent|GCG>GCC|A|91 silent|GCG>GCA|A|91 A|91|P A|91|T 0 0 0 0 -1.668576096734718 P34252 0.07134629786014557 0.4691264033317566 47.14464759924192 45.0 1.0 no 7198 chrXI_234679r 21374 essential YKL108W 256 - AATCGCCTTACCGTAAACTT silent|GCG>GCC|A|91 silent|GCG>GCA|A|91 A|91|P A|91|T 0 0 0 0 0.5843822961093827 P34252 0.07134629786014557 0.4691264033317566 45.755999023987606 40.0 1.0 no 7199 chrXI_234827r 21377 essential YKL108W 404 - GATCTGCAGGCGACGATTTT D|141|H D|141|N A|140|P A|140|T 0 1 0 0 -0.13832776317922585 P34252 0.056048423051834106 0.2314403206110001 0.2346579432487488 0.4571968317031861 50.198163588373916 50.0 1.0 no 7200 chrXI_234939 21380 essential YKL108W 513 + TCACCATGCAAGAATCGCAA P|173|A P|173|S S|172|* S|172|L 0 1 0 0 -0.7185532509127177 P34252 0.364461362361908 0.1703088879585266 0.0 45.82973936007159 45.0 1.0 no 7201 chrXI_235007 21381 essential YKL108W 581 + ACTAGAATCTGGCAAACCAT L|195|V silent|CTA>TTA|L|195 0 0 0 0 0.6580983037667422 P34252 43.47094084322072 40.0 1.0 no 7202 chrXI_235040 21382 essential YKL108W 614 + ACCTAATTCCCCGCTAAAAT P|206|R P|206|L P|206|A P|206|S 0 1 0 0 1.0187487595613385 P34252 0.0 0.0 0.0 0.0 47.16261360123025 40.0 1.0 no 7203 chrXI_235048r 21385 essential YKL108W 625 - TTCTTCATCCAATTTTAGCG E|215|Q E|215|K E|214|Q E|214|K 0 0 0 0 0.3816070016240283 P34252 0.2579783797264099 0.24617917835712436 0.553895115852356 0.8605429530143738 44.63137431762282 35.0 1.0 no 7204 chrXI_235049r 21386 essential YKL108W 626 - TTTCTTCATCCAATTTTAGC E|215|Q E|215|K E|214|Q E|214|K 0 0 0 0 0.418910351177948 P34252 0.2579783797264099 0.24617917835712436 0.553895115852356 0.8605429530143738 43.62605104785655 30.0 1.0 no 7205 chrXI_235223r 21391 essential YKL108W 800 - GTTCCCTGGCCAATTCTATC E|273|Q E|273|K R|272|S silent|AGG>AGA|R|272 0 0 0 0 0.08657435955522724 P34252 0.0 0.0 0.1444745808839798 55.802169071377705 50.0 1.0 no 7206 chrXI_243774 21397 essential YKL104C 1580 - TTCTGTCTATTTTCGATACA R|533|T R|533|K D|532|H D|532|N GFA1 Glutamine:Fructose-6-phosphate Amidotransferase 717.0 0 0 0 0 0.6338306354813292 P14742 0.932735025882721 0.955805003643036 0.9486550092697144 0.956179976463318 0.004138643853366375 0.10976965725421907 0.11112914979457857 0.4982873797416687 42.37798772611393 30.0 0.0 no 7207 chrXI_243819 21398 essential YKL104C 1535 - ACATCACTAAGGCAATATAC M|518|I M|518|I silent|GTG>GTC|V|517 silent|GTG>GTA|V|517 GFA1 Glutamine:Fructose-6-phosphate Amidotransferase 717.0 0 0 0 0 -2.015713672933672 P14742 0.9553959965705872 0.9553959965705872 0.05390958487987518 0.05390958487987518 38.856404970449255 35.0 0.0 yes 7208 chrXI_243899r 21400 essential YKL104C 1452 + ATCTCTCGTGTCACCCACTG I|485|M silent|ATC>ATT|I|485 S|486|C S|486|F GFA1 Glutamine:Fructose-6-phosphate Amidotransferase 717.0 0 0 0 0 0.1336122303133137 P14742 0.9598389863967896 0.945252001285553 0.9294660091400146 0.026110026985406883 0.2404119819402695 0.013513712212443352 -0.999119997024536 56.3580715434951 55.00000000000001 0.0 no 7209 chrXI_243973 21402 essential YKL104C 1381 - ACAATAATTTAGAGCCAGCA C|467|S C|467|Y GFA1 Glutamine:Fructose-6-phosphate Amidotransferase 717.0 0 0 0 0 -0.5307770827547786 P14742 0.9421560168266296 0.9290120005607604 0.04624716937541962 0.000899953069165349 42.586712792377064 35.0 0.0 no 7210 chrXI_244010r 21404 essential YKL104C 1341 + TGCGTGTTTGTTTCACAAAG C|448|W silent|TGC>TGT|C|448 GFA1 Glutamine:Fructose-6-phosphate Amidotransferase 717.0 0 0 0 0 -0.2315574948951873 P14742 0.9286419749259948 0.0008119511767290533 43.78700434550024 40.0 0.0 no 7211 chrXI_244077 21407 essential YKL104C 1277 - ACGCTAATTCCACACTAACT A|432|P A|432|T silent|GCG>GCC|A|432 silent|GCG>GCA|A|432 GFA1 Glutamine:Fructose-6-phosphate Amidotransferase 717.0 0 0 0 0 -6.853686466380163 P14742 0.9573720097541808 0.9523990154266356 0.0051328660920262345 0.003603559453040362 1.1877800226211548 2.655980110168457 44.88844144697589 40.0 0.0 yes 7212 chrXI_244086r 21408 essential YKL104C 1265 + ATCAGATATCCCAGTTAGTG S|423|* S|423|L GFA1 Glutamine:Fructose-6-phosphate Amidotransferase 717.0 0 0 0 0 -2.2415821310089816 P14742 0.9298099875450134 0.11577801406383514 47.22919169709138 40.0 0.0 yes 7213 chrXI_244256r 21410 essential YKL104C 1095 + TCTACTTTCAATACTATGAG S|366|C S|366|F T|367|S T|367|I GFA1 Glutamine:Fructose-6-phosphate Amidotransferase 717.0 0 0 0 0 -0.23628333081542624 P14742 0.945252001285553 0.9294660091400146 0.9491789937019348 0.9472420215606691 0.0013297742698341608 0.0006148236570879817 0.051427628844976425 0.2951022982597351 37.282214707826206 30.0 0.0 no 7214 chrXI_244450 21411 essential YKL104C 904 - TTCTAAAAATAGCACCTTCT E|308|Q E|308|K GFA1 Glutamine:Fructose-6-phosphate Amidotransferase 717.0 0 0 0 0 -0.02796790705193747 P14742 0.956179976463318 0.9475290179252625 0.005405189469456673 0.004688788205385208 39.56845914006385 30.0 0.0 no 7215 chrXI_244505 21412 essential YKL104C 849 - ACAAAAAATTCCACCGGTGT V|290|L V|290|I GFA1 Glutamine:Fructose-6-phosphate Amidotransferase 717.0 0 0 0 0 -0.7854050211674448 P14742 0.9539830088615416 0.9574310183525084 0.9765447974205016 0.7942436933517456 42.977618469766576 40.0 0.0 no 7216 chrXI_244567 21414 essential YKL104C 787 - TCTCAAGTTAAATTCATTGG L|268|F silent|TTG>TTA|L|268 R|269|T R|269|K GFA1 Glutamine:Fructose-6-phosphate Amidotransferase 717.0 0 0 0 0 0.10293161198556564 P14742 0.9587849974632264 0.932735025882721 0.955805003643036 0.4470157623291016 0.5631259679794312 0.9590764045715332 37.25972787013541 30.0 0.0 no 7217 chrXI_244625 21416 essential YKL104C 729 - TCAAATTCACGAGCTTTCTT E|250|Q E|250|K GFA1 Glutamine:Fructose-6-phosphate Amidotransferase 717.0 0 1 0 0 0.7627404119265032 P14742 0.956179976463318 0.9475290179252625 0.640475332736969 0.9382528066635132 43.06336757423799 35.0 0.0 no 7218 chrXI_244649r 21417 essential YKL104C 702 + AACAACAAATCATTTGGCTT N|235|K silent|AAC>AAT|N|235 N|236|K silent|AAC>AAT|N|236 GFA1 Glutamine:Fructose-6-phosphate Amidotransferase 717.0 0 1 0 0 0.15912360914368975 P14742 0.9439849853515624 0.9439849853515624 0.9036152958869934 0.916820228099823 38.135644860425145 30.0 0.0 no 7219 chrXI_244650r 21418 essential YKL104C 701 + TAACAACAAATCATTTGGCT N|235|K silent|AAC>AAT|N|235 N|236|K silent|AAC>AAT|N|236 GFA1 Glutamine:Fructose-6-phosphate Amidotransferase 717.0 0 1 0 0 -0.4507574878238999 P14742 0.9439849853515624 0.9439849853515624 0.9036152958869934 0.916820228099823 37.404141019524495 30.0 0.0 no 7220 chrXI_244800r 21419 essential YKL104C 551 + ATCTTGTCACTATCCTAATG S|185|C S|185|F GFA1 Glutamine:Fructose-6-phosphate Amidotransferase 717.0 0 0 0 0 0.02718280825187902 P14742 0.945252001285553 0.9294660091400146 0.0019478359026834367 0.0019192754989489913 43.33852691882703 35.0 0.0 no 7221 chrXI_244897r 21421 essential YKL104C 454 + ACAATACAAATTTACAAAAT Y|152|* silent|TAC>TAT|Y|152 T|154|R T|154|I GFA1 Glutamine:Fructose-6-phosphate Amidotransferase 717.0 0 0 0 0 -0.06037723962024494 P14742 0.9476869702339172 0.9472420215606691 0.4869836270809174 0.1139056459069252 27.54101443915345 15.0 0.0 no 7222 chrXI_245052 21425 essential YKL104C 302 - CTTCTGGGTCAGATCTTTGA E|107|Q E|107|K GFA1 Glutamine:Fructose-6-phosphate Amidotransferase 717.0 0 0 0 0 -0.9478800271840612 P14742 0.956179976463318 0.9475290179252625 0.4027514457702637 0.915481984615326 49.959974744263256 45.0 0.0 no 7223 chrXI_245141 21426 essential YKL104C 213 - ACAAAAGTAACGTCTCTGTT V|78|L V|78|I GFA1 Glutamine:Fructose-6-phosphate Amidotransferase 717.0 0 0 0 0 -0.24476086878759584 P14742 0.9539830088615416 0.9574310183525084 0.33225688338279724 0.21266993880271912 39.691093037439366 35.0 0.0 no 7224 chrXI_245239 21428 essential YKL104C 115 - GTCACCATCGATAGCAATAC D|45|H D|45|N G|44|A G|44|D GFA1 Glutamine:Fructose-6-phosphate Amidotransferase 717.0 0 0 0 0 -0.9196538143386856 P14742 0.9486550092697144 0.956179976463318 0.9499930143356324 0.9446240067481996 0.04901393130421639 0.3173867762088776 0.1072637289762497 0.29741889238357544 45.873780971024935 45.0 0.0 no 7225 chrXI_245242 21429 essential YKL104C 112 - ACCATCGATAGCAATACCGG G|44|R G|44|S G|44|A G|44|D GFA1 Glutamine:Fructose-6-phosphate Amidotransferase 717.0 0 0 0 0 -5.036355938585314 P14742 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.015441768802702429 0.15216250717639926 0.1072637289762497 0.29741889238357544 48.13180514441473 50.0 0.0 yes 7226 chrXI_245243r 21430 essential YKL104C 108 + TCCACCGGTATTGCTATCGA silent|TCC>TCG|S|37 silent|TCC>TCT|S|37 S|37|C S|37|F GFA1 Glutamine:Fructose-6-phosphate Amidotransferase 717.0 0 0 0 0 -0.075619942480923 P14742 0.945252001285553 0.9294660091400146 0.0019125581020489333 0.0008546799654141067 53.3549820887261 50.0 0.0 no 7227 chrXI_245273r 21431 essential YKL104C 78 + TTACAAAGATTAGAATATAG Q|28|E Q|28|* GFA1 Glutamine:Fructose-6-phosphate Amidotransferase 717.0 0 0 0 0 0.9736188549126004 P14742 0.9590039849281312 0.5024475455284119 28.12220496019876 20.0 0.0 no 7228 chrXI_245287 21432 essential YKL104C 67 - TCTTTGTAAACCATCCACTA R|29|T R|29|K GFA1 Glutamine:Fructose-6-phosphate Amidotransferase 717.0 0 0 0 0 0.4537799298148013 P14742 0.932735025882721 0.955805003643036 0.006465302780270577 0.10119117796421052 44.91623880387078 35.0 0.0 no 7229 chrXI_255911r 21435 essential YKL099C 539 + CGCTTCATCAATAATGCCAA A|181|G A|181|V S|182|* S|182|L UTP11 U Three Protein 250.0 0 0 0 0 -0.3946023106042512 P34247 0.9484469890594482 0.9504740238189696 0.9298099875450134 0.4528685808181762 0.4389701783657074 0.3092140257358551 44.463021124608815 40.0 0.0 no 7230 chrXI_255936 21436 essential YKL099C 517 - CCTATTGTTTGAAATATCTT R|179|T R|179|K UTP11 U Three Protein 250.0 0 0 0 0 -0.20114178436314006 P34247 0.932735025882721 0.955805003643036 0.5765329599380493 1.0 38.42047192246292 25.0 0.0 no 7231 chrXI_255936r 21437 essential YKL099C 514 + CCCAAGATATTTCAAACAAT Q|173|E Q|173|* silent|GCC>GCG|A|172 silent|GCC>GCT|A|172 UTP11 U Three Protein 250.0 0 1 0 0 1.0757981817024458 P34247 0.9590039849281312 0.9100628495216371 38.21109623492657 30.0 0.0 no 7232 chrXI_255968r 21438 essential YKL099C 482 + ATCTGAAAATAGATTAACTA S|162|C S|162|F UTP11 U Three Protein 250.0 0 0 0 0 -0.07085825963148243 P34247 0.945252001285553 0.9294660091400146 0.023339005187153816 0.03446878492832184 30.251258860401837 20.0 0.0 no 7233 chrXI_255984 21439 essential YKL099C 469 - TTCAGATCTATTCACCATCT E|163|Q E|163|K UTP11 U Three Protein 250.0 0 0 0 0 -0.18767109682244096 P34247 0.956179976463318 0.9475290179252625 0.42884695529937744 0.5481347441673279 46.348981475673206 35.0 0.0 no 7234 chrXI_255990 21440 essential YKL099C 463 - TCTATTCACCATCTCGGAGG R|161|T R|161|K silent|GTG>GTC|V|159 silent|GTG>GTA|V|159 UTP11 U Three Protein 250.0 0 0 0 0 -0.5775141445863905 P34247 0.932735025882721 0.955805003643036 0.040960729122161865 0.52523273229599 50.804694352434474 50.0 0.0 no 7235 chrXI_255998r 21441 essential YKL099C 452 + TTTCAATACCACCTCCGAGA F|152|L silent|TTC>TTT|F|152 UTP11 U Three Protein 250.0 0 0 0 0 0.6713361688061241 P34247 0.9387490153312684 0.0 49.822935222470505 45.0 0.0 no 7236 chrXI_256222r 21444 essential YKL099C 228 + CTGCTGATCAGCTCACGTCA L|78|V silent|CTG>TTG|L|78 UTP11 U Three Protein 250.0 0 0 0 0 -0.1809787193808564 P34247 0.9512209892272948 0.6013140678405762 54.68235631017507 55.00000000000001 0.0 no 7237 chrXI_256263r 21445 essential YKL099C 187 + ACTACCATGCTATGCATTCA Y|63|* silent|TAC>TAT|Y|63 Y|64|* silent|TAC>TAT|Y|64 UTP11 U Three Protein 250.0 0 0 0 0 -0.03246709053625306 P34247 48.964318903799715 40.0 0.0 no 7238 chrXI_256328 21448 essential YKL099C 125 - TCAAAGTGGACTGCTTCCTG L|48|F silent|TTG>TTA|L|48 UTP11 U Three Protein 250.0 0 0 0 0 -1.4414482478691468 P34247 0.9587849974632264 0.025625864043831825 49.30083621031639 50.0 0.0 no 7239 chrXI_262387r 21452 essential YKL095W 113 - TCATTAATCTAATCGATGCG M|44|I M|44|I YJU2 278.0 0 0 0 0 0.3815841846104692 P28320 0.0 0.0 39.16566604636176 35.0 1.0 no 7240 chrXI_262411r 21454 essential YKL095W 137 - CCAAACACCTCATACTAAAT L|52|F silent|TTG>TTA|L|52 C|51|S C|51|Y YJU2 278.0 0 0 0 0 0.5179802655897018 P28320 0.05988936126232147 0.0 0.0 40.18426854225589 35.0 1.0 no 7241 chrXI_262412r 21455 essential YKL095W 138 - TCCAAACACCTCATACTAAA L|52|F silent|TTG>TTA|L|52 E|53|Q E|53|K YJU2 278.0 0 0 0 0 0.3852290020929988 P28320 0.05988936126232147 0.3050373196601868 1.0 40.99650973678332 35.0 1.0 no 7242 chrXI_262452r 21456 essential YKL095W 178 - ACCATTGAATTTTCTGCTTT G|66|R G|66|S G|66|A G|66|D YJU2 278.0 0 0 0 0 0.4377942474982415 P28320 0.010451032780110836 0.06724795699119568 0.448419451713562 0.014803693629801272 44.33536476473631 30.0 1.0 no 7243 chrXI_262576r 21464 essential YKL095W 302 - TTACATAATCTGAATTACCG V|107|L V|107|I YJU2 278.0 0 0 0 0 0.6519764168045137 P28320 0.11093973368406296 0.3529340326786041 37.01841154273899 30.0 1.0 no 7244 chrXI_273412 21465 essential YKL089W 18 + GGGCTTAAGTCCCGTAAAAC L|8|V L|8|F MIF2 MItotic Fidelity of chromosome transmission 549.0 0 0 0 0 -0.7105522766949456 P35201 0.9950990080833436 1.0031700134277344 1.0 0.017280342057347298 47.74551349948536 50.0 1.0 no 7245 chrXI_273423r 21467 essential YKL089W 32 - TAACATCAATACCAGTTTTA V|17|L V|17|I D|16|H D|16|N MIF2 MItotic Fidelity of chromosome transmission 549.0 0 0 0 0 0.32522481660497105 P35201 0.9940739870071412 1.0010499954223633 0.9899479746818542 1.0004899501800537 0.14194229245185852 0.19739633798599246 0.06001391634345055 1.0 37.733009905008544 25.0 1.0 no 7246 chrXI_273457r 21468 essential YKL089W 66 - TCCATGCTGTATTCATCTTT M|28|I M|28|I E|29|Q E|29|K MIF2 MItotic Fidelity of chromosome transmission 549.0 0 1 0 0 0.3785979468171839 P35201 0.999705970287323 0.999705970287323 1.0004899501800537 0.9891330003738404 0.0 0.0 0.0 0.0 48.9161182558143 35.0 1.0 no 7247 chrXI_273559 21469 essential YKL089W 165 + TTCTTACCATCAACGTTAAA F|56|L silent|TTC>TTT|F|56 P|58|A P|58|S MIF2 MItotic Fidelity of chromosome transmission 549.0 0 1 0 0 0.4363727039459611 P35201 0.9824680089950562 1.0004199743270874 0.9926369786262512 0.8659772872924805 0.8752599358558655 0.5238027572631836 39.6210592460659 30.0 1.0 no 7248 chrXI_273652r 21470 essential YKL089W 261 - GATCCATCGCCTTTCCCAGA G|93|A G|93|E G|93|R G|93|R MIF2 MItotic Fidelity of chromosome transmission 549.0 0 0 0 0 0.5695496022674695 P35201 0.9903749823570251 0.9759219884872437 0.9727219939231871 0.9727219939231871 0.9297330379486084 1.0 0.6385834813117981 0.6385834813117981 59.23825876012336 55.00000000000001 1.0 no 7249 chrXI_273696r 21471 essential YKL089W 305 - GACTCAGGAAGTTTGATTGA S|108|T S|108|N silent|CTG>CTC|L|107 silent|CTG>CTA|L|107 MIF2 MItotic Fidelity of chromosome transmission 549.0 0 0 0 0 0.13993768974111925 P35201 0.9914429783821106 0.99549400806427 0.6797325015068054 0.5295775532722473 42.86080850149944 40.0 1.0 no 7250 chrXI_273796r 21473 essential YKL089W 405 - TTACTCAATTTCTGTGTGAT S|141|T S|141|N L|140|F silent|TTG>TTA|L|140 MIF2 MItotic Fidelity of chromosome transmission 549.0 0 0 0 0 -0.12820923759221872 P35201 0.9916689991950988 0.9957190155982972 1.0031700134277344 0.1152755171060562 0.14027611911296844 0.2743536531925201 41.374761899697255 30.0 1.0 no 7251 chrXI_273874r 21475 essential YKL089W 483 - TCAGGTGTCAACCTTACAGA D|168|H D|168|N MIF2 MItotic Fidelity of chromosome transmission 549.0 0 1 0 0 0.897118672412772 P35201 0.9899479746818542 1.0004899501800537 0.045261949300765984 0.2880910634994507 48.80811561966732 45.0 1.0 no 7252 chrXI_274245 21478 essential YKL089W 851 + TCGGAAATCTACAAGAGTCA R|285|G R|285|W MIF2 MItotic Fidelity of chromosome transmission 549.0 0 0 0 0 -0.30712690521082503 P35201 0.9377340078353882 0.9694820046424866 0.0 0.0 40.78087214146996 40.0 1.0 no 7253 chrXI_274429r 21480 essential YKL089W 1038 - ACGTAGTTGTAAGGTCTGGT V|353|L V|353|I MIF2 MItotic Fidelity of chromosome transmission 549.0 0 1 0 0 -2.6003156894677693 P35201 0.9693499803543092 0.9770190119743348 0.28502157330513 1.0 49.20824108867754 45.0 1.0 yes 7254 chrXI_274437 21481 essential YKL089W 1043 + ACCTTACAACTACGTACCTA P|349|R P|349|L P|349|A P|349|S MIF2 MItotic Fidelity of chromosome transmission 549.0 0 0 0 0 0.05451164783191503 P35201 0.95032000541687 0.9589239954948424 0.9763929843902588 0.9679129719734192 0.047365132719278336 0.4329078197479248 0.16621699929237366 0.08305411040782927 46.10213984350918 40.0 1.0 no 7255 chrXI_274438 21482 essential YKL089W 1044 + CCTTACAACTACGTACCTAC P|349|R P|349|L Y|350|* silent|TAC>TAT|Y|350 MIF2 MItotic Fidelity of chromosome transmission 549.0 0 0 0 0 -0.3149684188415142 P35201 0.95032000541687 0.9589239954948424 0.047365132719278336 0.4329078197479248 46.10213984350918 45.0 1.0 no 7256 chrXI_275301 21487 essential YKL088W 18 + AACTCAGATCAGAATATGAA N|7|K silent|AAC>AAT|N|7 S|8|* S|8|L CAB3 Coenzyme A Biosynthesis 571.0 0 1 0 0 0.8056503613546493 P36076 0.9439849853515624 0.9298099875450134 35.06386166758284 30.0 1.0 no 7257 chrXI_275455 21490 essential YKL088W 172 + AATCAAAATCCAACTCTAAT S|59|* S|59|L CAB3 Coenzyme A Biosynthesis 571.0 0 1 0 0 -0.787388549276675 P36076 0.9298099875450134 34.31122224257632 25.0 1.0 no 7258 chrXI_275386r 21491 essential YKL088W 106 - ACTTTTTCTTCTCTCCTTGT S|42|T S|42|N CAB3 Coenzyme A Biosynthesis 571.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.5482442696704155 P36076 0.9512869715690612 0.9536849856376648 51.331100970646666 35.0 1.0 no 7259 chrXI_275530r 21492 essential YKL088W 250 - TTCACTATTTTGCTTCAGAT E|90|Q E|90|K S|89|T S|89|N CAB3 Coenzyme A Biosynthesis 571.0 0 0 0 0 -0.6684871374279575 P36076 0.956179976463318 0.9475290179252625 0.9512869715690612 0.9536849856376648 43.503163125219096 30.0 1.0 no 7260 chrXI_275595r 21494 essential YKL088W 315 - TGCTGGCCATTTGTATTAGC Q|111|H silent|CAG>CAA|Q|111 G|110|A G|110|D CAB3 Coenzyme A Biosynthesis 571.0 0 0 0 0 0.3607955028476834 P36076 0.9570760130882264 0.9499930143356324 0.9446240067481996 0.1175920143723488 0.3336435556411743 0.08256717026233673 52.076725930526884 45.0 1.0 no 7261 chrXI_275602 21495 essential YKL088W 319 + ATACAAATGGCCAGCAAAAA T|108|R T|108|I CAB3 Coenzyme A Biosynthesis 571.0 0 0 0 0 1.3575000382925348 P36076 0.9476869702339172 0.9472420215606691 0.06893016397953032 0.04186548292636871 38.51392982140403 35.0 1.0 no 7262 chrXI_275664r 21498 essential YKL088W 384 - TACGGCAACCTTTCCACCTC silent|CCG>CCC|P|134 silent|CCG>CCA|P|134 L|133|F silent|TTG>TTA|L|133 CAB3 Coenzyme A Biosynthesis 571.0 0 0 0 0 0.24214951832289602 P36076 0.9587849974632264 0.05503162741661072 55.33180289690932 55.00000000000001 1.0 no 7263 chrXI_275665r 21499 essential YKL088W 385 - ATACGGCAACCTTTCCACCT silent|CCG>CCC|P|134 silent|CCG>CCA|P|134 L|133|F silent|TTG>TTA|L|133 CAB3 Coenzyme A Biosynthesis 571.0 0 0 0 0 0.04002119305847809 P36076 0.9587849974632264 0.05503162741661072 54.218513727966005 50.0 1.0 no 7264 chrXI_275704r 21500 essential YKL088W 424 - CTGCTGCTTTCCAGGTTTAT Q|147|H silent|CAG>CAA|Q|147 K|146|N silent|AAG>AAA|K|146 CAB3 Coenzyme A Biosynthesis 571.0 0 0 0 0 0.8577465317105469 P36076 0.9570760130882264 0.9355990290641784 0.12321532517671585 0.4226202666759491 54.08935413444158 45.0 1.0 no 7265 chrXI_275867 21504 essential YKL088W 584 + ACAGCAACTGATAGACGAAA Q|196|E Q|196|* Q|197|E Q|197|* CAB3 Coenzyme A Biosynthesis 571.0 0 0 0 0 -1.6722191820914247 P36076 0.9590039849281312 0.9590039849281312 1.0 1.0 39.079926875919796 40.0 1.0 no 7266 chrXI_275936 21505 essential YKL088W 653 + TACTGATATCAGGAAACATT T|219|S T|219|I CAB3 Coenzyme A Biosynthesis 571.0 0 1 0 0 -0.1306763764604602 P36076 0.9491789937019348 0.9472420215606691 1.0 0.10772403329610823 36.778755194706825 30.0 1.0 no 7267 chrXI_276071 21506 essential YKL088W 788 + TTCTAAACCTATCACTGCAA S|264|C S|264|F CAB3 Coenzyme A Biosynthesis 571.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.4233636506546631 P36076 0.945252001285553 0.9294660091400146 0.043940186500549316 0.04739464446902275 42.361266691177214 35.0 1.0 no 7268 chrXI_276113 21508 essential YKL088W 830 + TAACTCCACACATAAAAACA N|278|K silent|AAC>AAT|N|278 S|279|C S|279|F CAB3 Coenzyme A Biosynthesis 571.0 0 0 0 0 -0.04473515197255022 P36076 0.9439849853515624 0.945252001285553 0.9294660091400146 0.9963612556457521 0.046347521245479584 0.04496563225984573 35.504345031466926 30.0 1.0 no 7269 chrXI_276118r 21509 essential YKL088W 838 - AACTTCCTTGTTTTTATGTG V|286|L V|286|I E|285|Q E|285|K CAB3 Coenzyme A Biosynthesis 571.0 0 0 0 0 -0.017973194576244134 P36076 0.9539830088615416 0.9574310183525084 0.956179976463318 0.9475290179252625 0.22157737612724304 1.0 0.5273380875587463 0.868896484375 42.59376338239389 30.0 1.0 no 7270 chrXI_276170 21511 essential YKL088W 887 + CTTCACAGAGTTCTTTCAGA F|297|L silent|TTC>TTT|F|297 T|298|R T|298|I CAB3 Coenzyme A Biosynthesis 571.0 0 0 0 0 1.2431721343034 P36076 0.9387490153312684 0.9476869702339172 0.9472420215606691 0.0 0.34960776567459106 0.3517288565635681 46.55986326277628 40.0 1.0 no 7271 chrXI_276209 21512 essential YKL088W 926 + CCACATTCTCATTGGTGCGA H|310|Q silent|CAC>CAT|H|310 H|310|D H|310|Y CAB3 Coenzyme A Biosynthesis 571.0 0 0 0 0 -0.06659109623094123 P36076 0.9588389992713928 0.9473130106925964 0.9489949941635132 0.0 0.0 0.0 52.63102933867401 50.0 1.0 no 7272 chrXI_276210 21514 essential YKL088W 927 + CACATTCTCATTGGTGCGAC H|310|Q silent|CAC>CAT|H|310 L|312|V L|312|F CAB3 Coenzyme A Biosynthesis 571.0 0 0 0 0 0.2851909546176264 P36076 0.9588389992713928 0.9512209892272948 0.9587849974632264 0.0 0.0 0.0 49.383073104506934 50.0 1.0 no 7273 chrXI_276291r 21515 essential YKL088W 1011 - AACTGAATAGAGATTTTCTC Q|343|H silent|CAG>CAA|Q|343 CAB3 Coenzyme A Biosynthesis 571.0 0 0 0 0 -1.050983841866952 P36076 0.9570760130882264 0.0027526633348315954 36.06158720162415 30.0 1.0 no 7274 chrXI_276327r 21516 essential YKL088W 1047 - CCTTTCAAAAAATGCTCAGC G|356|R G|356|R L|354|F silent|TTG>TTA|L|354 CAB3 Coenzyme A Biosynthesis 571.0 0 0 0 0 0.1485966691307171 P36076 0.941340982913971 0.941340982913971 0.9587849974632264 0.0 0.0 0.00819794274866581 41.80939691914932 40.0 1.0 no 7275 chrXI_276361 21518 essential YKL088W 1078 + CAACACACGTTAAAATTTGG T|361|R T|361|I H|362|D H|362|Y CAB3 Coenzyme A Biosynthesis 571.0 0 0 0 0 0.0229823766393802 P36076 0.9476869702339172 0.9472420215606691 0.9473130106925964 0.9489949941635132 0.04520614445209503 0.02073326520621777 1.0 0.032100152224302285 35.96357470047377 35.0 1.0 no 7276 chrXI_276362 21519 essential YKL088W 1079 + AACACACGTTAAAATTTGGA T|361|R T|361|I H|362|D H|362|Y CAB3 Coenzyme A Biosynthesis 571.0 0 0 0 0 -0.4312920586098756 P36076 0.9476869702339172 0.9472420215606691 0.9473130106925964 0.9489949941635132 0.04520614445209503 0.02073326520621777 1.0 0.032100152224302285 35.789151848202664 30.0 1.0 no 7277 chrXI_281360r 21525 essential YKL082C 947 + ACTAGAACAAATCAAGCAGA L|317|V silent|CTA>TTA|L|317 RRP14 Ribosomal RNA Processing 434.0 0 0 0 0 0.9016844755672156 P36080 0.057691723108291626 36.95636278236822 35.0 0.0 no 7278 chrXI_281481 21528 essential YKL082C 829 - TAACCTTTGTAAATCTGAAG R|282|S silent|AGG>AGA|R|282 R|282|T R|282|K RRP14 Ribosomal RNA Processing 434.0 0 0 0 0 0.09839154239804844 P36080 0.8254439830780029 0.5783712863922119 1.0 35.81743856825756 30.0 0.0 no 7279 chrXI_281484r 21529 essential YKL082C 823 + GGGCCACTTCAGATTTACAA A|276|G A|276|V silent|GCC>GCG|A|276 silent|GCC>GCT|A|276 RRP14 Ribosomal RNA Processing 434.0 0 0 0 0 -1.7082761139589695 P36080 0.0044076452031731606 1.0 49.082274759491675 45.0 0.0 no 7280 chrXI_281505r 21530 essential YKL082C 802 + TCATATTCGATGATGGTGCA I|268|M silent|ATC>ATT|I|268 RRP14 Ribosomal RNA Processing 434.0 0 0 0 0 -0.1603029050035808 P36080 0.0 45.71611432264433 40.0 0.0 no 7281 chrXI_281613 21531 essential YKL082C 697 - ACTATCGATGTCTTCCATAT S|239|T S|239|N D|238|H D|238|N RRP14 Ribosomal RNA Processing 434.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.8806917988203785 P36080 0.1535617858171463 0.4324507415294647 0.028458591550588608 0.10494662076234818 45.5261744795489 35.0 0.0 no 7282 chrXI_281850 21536 essential YKL082C 460 - CTTCTTTTCGACAGATCTAT K|159|N silent|AAG>AAA|K|159 RRP14 Ribosomal RNA Processing 434.0 0 0 0 0 0.9906227919170616 P36080 0.035503122955560684 43.554221640116 35.0 0.0 no 7283 chrXI_281851 21537 essential YKL082C 459 - TTCTTTTCGACAGATCTATC K|159|N silent|AAG>AAA|K|159 RRP14 Ribosomal RNA Processing 434.0 0 0 0 0 0.04721186471048028 P36080 0.035503122955560684 42.65820839013623 35.0 0.0 no 7284 chrXI_282140 21540 essential YKL082C 170 - TTTCATCATCACGTTGCTCC E|63|Q E|63|K D|62|H D|62|N RRP14 Ribosomal RNA Processing 434.0 0 0 0 0 -0.06233568307866881 P36080 0.5407340526580809 0.7898933291435242 0.08270101994276048 0.8936980962753296 51.59860039356551 45.0 0.0 no 7285 chrXI_282180 21541 essential YKL082C 130 - ATCATTTTTACTCTGTTCTT D|50|H D|50|N RRP14 Ribosomal RNA Processing 434.0 0 1 0 0 1.0472355298476097 P36080 0.05392405390739441 0.6870390176773071 42.75001267440121 25.0 0.0 no 7286 chrXI_282284 21545 essential YKL082C 26 - AGGCGCTTGAATTAGCACGA A|15|P A|15|T S|14|T S|14|N RRP14 Ribosomal RNA Processing 434.0 0 0 0 0 -0.8398951160714075 P36080 0.016311924904584885 0.015732180327177048 0.3657746911048889 1.0 49.290929019561595 50.0 0.0 no 7287 chrXI_285301 21548 high_effect YKL080W 271 + AGACCAGCACCAATGCTTAC T|92|S T|92|I silent|ACC>ACG|T|92 silent|ACC>ACT|T|92 VMA5 Vacuolar Membrane Atpase 392.0 0 0 0 0 0.7149801515360132 P31412 0.9491789937019348 0.9472420215606691 0.13704676926136014 0.02094532363116741 1.0900199413299558 1.5898200273513794 50.61684240068161 50.0 1.0 no 7288 chrXI_285457r 21550 high_effect YKL080W 430 - TGCATAAGTAGCTCTGACGT A|150|P A|150|T VMA5 Vacuolar Membrane Atpase 392.0 0 0 0 0 -1.1295023634143293 P31412 0.9573720097541808 0.9523990154266356 0.14431993663311005 1.0 3.1194000244140625 0.07885999977588654 3.686079978942871 0.26673999428749084 47.9460722393036 45.0 1.0 no 7289 chrXI_285694r 21556 high_effect YKL080W 667 - AGCATCCTCTGCAATCACGC A|229|P A|229|T D|228|H D|228|N VMA5 Vacuolar Membrane Atpase 392.0 0 0 0 0 0.9639366364008868 P31412 0.9573720097541808 0.9523990154266356 0.9486550092697144 0.956179976463318 0.03635236248373985 0.038353070616722114 0.0 0.0 -0.7381600141525269 -0.015599999576807022 1.5329999923706057 0.803879976272583 0.023879999294877045 0.4122200012207031 54.62050130444288 55.00000000000001 1.0 no 7290 chrXI_285797 21557 high_effect YKL080W 767 + TCCTCGTGAATTTAACTACT P|257|R P|257|L P|257|A P|257|S VMA5 Vacuolar Membrane Atpase 392.0 0 1 0 0 0.6498069747177007 P31412 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.02365606278181076 0.10595998913049698 0.21086613833904266 0.10985331982374193 4.050559997558594 2.889620065689087 3.25816011428833 4.394020080566406 42.78595329551422 35.0 1.0 no 7291 chrXI_285798r 21558 high_effect YKL080W 771 - TCCGAGTAGTTAAATTCACG silent|TCG>TCC|S|263 silent|TCG>TCA|S|263 E|264|Q E|264|K VMA5 Vacuolar Membrane Atpase 392.0 0 0 0 0 -0.3526581192116286 P31412 0.956179976463318 0.9475290179252625 0.030844643712043762 0.10851410031318663 0.5671399831771851 0.5420600175857544 42.147506371599825 40.0 1.0 no 7292 chrXI_285872 21560 high_effect YKL080W 842 + ACAATCTTTGCGCGTCCAGT Q|282|E Q|282|* S|283|C S|283|F VMA5 Vacuolar Membrane Atpase 392.0 0 0 0 0 1.4652201469850787 P31412 0.9590039849281312 0.945252001285553 0.9294660091400146 0.02111763320863247 0.003315959125757217 0.005232998635619879 0.5702599883079529 0.5562199950218201 -1.0205999612808228 53.50994979019106 50.0 1.0 no 7293 chrXI_285904r 21562 high_effect YKL080W 877 - AACATCGACATAAGCTGTCT V|299|L V|299|I D|298|H D|298|N VMA5 Vacuolar Membrane Atpase 392.0 0 0 0 0 0.5356274122787452 P31412 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 0.3861182630062103 0.5879417657852173 0.007686849217861891 0.016288381069898602 -0.4031200110912323 -0.7128000259399414 -0.7223799824714661 -0.9072200059890748 43.45023396595282 40.0 1.0 no 7294 chrXI_288880 21563 essential YKL078W 35 + CCATACTTCTAAAAAACAAA H|13|D H|13|Y T|14|S T|14|I DHR2 DEAH-box RNA helicase 735.0 0 0 0 0 0.06328038467198738 P36009 0.6303755640983582 0.22548122704029086 0.7437074184417725 0.19686029851436612 31.977541863758407 25.0 1.0 no 7295 chrXI_288997 21564 essential YKL078W 152 + TTCAGACCAACGTTCGAACA S|52|* S|52|L D|53|E silent|GAC>GAT|D|53 DHR2 DEAH-box RNA helicase 735.0 0 0 0 0 -0.5287025628433416 P36009 0.3044633865356445 1.0 45.20007060451093 45.0 1.0 no 7296 chrXI_289089r 21565 essential YKL078W 247 - TTCTCGCTTGTGTTGGTAAA E|89|Q E|89|K R|88|P R|88|Q DHR2 DEAH-box RNA helicase 735.0 0 0 0 0 -0.651530302095803 P36009 0.29871127009391785 0.4603070616722107 0.1805766373872757 0.3757236897945404 46.89507615250625 40.0 1.0 no 7297 chrXI_289133 21567 essential YKL078W 288 + AATCCCGTTACCGTCCTTAT P|98|A P|98|S P|98|R P|98|L DHR2 DEAH-box RNA helicase 735.0 0 1 0 0 -0.2953927152948622 P36009 0.4845401644706726 0.5370823144912721 0.5055500864982605 0.1923426389694214 53.44049644162215 45.0 1.0 no 7298 chrXI_289243 21570 essential YKL078W 398 + AACTCAACCCCGTCGTGTTG T|134|S T|134|I Q|135|E Q|135|* DHR2 DEAH-box RNA helicase 735.0 0 0 0 0 -0.6093273925903875 P36009 0.0 0.0 0.0 53.17628809614172 55.00000000000001 1.0 no 7299 chrXI_289367 21574 essential YKL078W 522 + AGACTTAAGTATCTGACTGA L|176|V L|176|F DHR2 DEAH-box RNA helicase 735.0 0 0 0 0 -0.5740579920734621 P36009 0.2204650640487671 0.008121812716126442 40.29204604763385 35.0 1.0 no 7300 chrXI_289496 21575 essential YKL078W 651 + TTCTTAAAATCCTTGATACA F|218|L silent|TTC>TTT|F|218 DHR2 DEAH-box RNA helicase 735.0 0 0 0 0 0.4583225488641069 P36009 0.33270543813705444 37.12766748066025 25.0 1.0 no 7301 chrXI_289473 21576 essential YKL078W 628 + TGCTTACAGATTTGATATTG L|211|V L|211|F T|212|R T|212|I DHR2 DEAH-box RNA helicase 735.0 0 0 0 0 0.36942661899186974 P36009 0.4701338112354279 0.3498448431491852 0.012092501856386663 0.09544016420841216 38.76088501459071 30.0 1.0 no 7302 chrXI_289497 21577 essential YKL078W 652 + TCTTAAAATCCTTGATACAA F|218|L silent|TTC>TTT|F|218 DHR2 DEAH-box RNA helicase 735.0 0 0 0 0 0.6027110594518487 P36009 0.33270543813705444 35.673583052916854 25.0 1.0 no 7303 chrXI_289136r 21578 essential YKL078W 294 - TCACCAATAAGGACGGTAAC G|104|A G|104|D E|105|Q E|105|K DHR2 DEAH-box RNA helicase 735.0 0 1 0 0 -3.7697265518039207 P36009 0.0 0.0 0.0 0.0 42.37172626546271 45.0 1.0 yes 7304 chrXI_289598r 21579 essential YKL078W 756 - CTTCCTTCTACAAATAAGAT G|258|A G|258|E G|258|R G|258|R DHR2 DEAH-box RNA helicase 735.0 0 0 0 0 -0.27687352487827066 P36009 0.0 0.0 0.0 0.0 38.61639976432639 30.0 1.0 no 7305 chrXI_289630 21581 essential YKL078W 785 + TGTCAAACAATACTACTTGA silent|GTC>GTG|V|263 silent|GTC>GTT|V|263 DHR2 DEAH-box RNA helicase 735.0 0 0 0 0 0.4588210768967537 P36009 36.49195350382786 30.0 1.0 no 7306 chrXI_289705r 21582 essential YKL078W 863 - TATCTCCCAGTTCTTCACCT D|294|H D|294|N G|293|A G|293|E DHR2 DEAH-box RNA helicase 735.0 0 0 0 0 -0.6081893969686709 P36009 0.0 0.0 0.0 0.0 56.38049172984165 45.0 1.0 no 7307 chrXI_289759 21583 essential YKL078W 914 + TGACAAAGCAGTGACTATAA D|306|E silent|GAC>GAT|D|306 DHR2 DEAH-box RNA helicase 735.0 0 0 0 0 0.4687698323816839 P36009 1.0 37.88720527091505 35.0 1.0 no 7308 chrXI_289886r 21588 essential YKL078W 1044 - TTTCTCTTGAAACCCTTTAT R|354|T R|354|K K|353|N silent|AAG>AAA|K|353 DHR2 DEAH-box RNA helicase 735.0 0 0 0 0 -5.446597591335276 P36009 0.0 0.0 0.14176325500011444 43.71486954479883 30.0 1.0 yes 7309 chrXI_289947r 21589 essential YKL078W 1105 - GACAAATTTAACACCGGATA V|375|L V|375|I DHR2 DEAH-box RNA helicase 735.0 0 0 0 0 -0.3549755976292051 P36009 0.0 0.0 38.72010154227394 35.0 1.0 no 7310 chrXI_290029 21591 essential YKL078W 1184 + ACTTACCGTACCCATTTCTC L|396|V L|396|F T|397|S T|397|I DHR2 DEAH-box RNA helicase 735.0 0 0 0 0 -0.019058558646971285 P36009 0.08358804136514664 0.06444638222455977 0.0588853731751442 0.5843867063522339 52.28516535782597 45.0 1.0 no 7311 chrXI_290039r 21593 essential YKL078W 1197 - ATCGCACTTGCCTGAGAAAT silent|GCG>GCC|A|405 silent|GCG>GCA|A|405 A|405|P A|405|T DHR2 DEAH-box RNA helicase 735.0 0 0 0 0 -1.6764801102810922 P36009 0.0 0.0 47.456540471456144 45.0 1.0 no 7312 chrXI_290156r 21595 essential YKL078W 1314 - ACGTCACTTCTGGCTATTTC V|445|L V|445|I D|444|H D|444|N DHR2 DEAH-box RNA helicase 735.0 0 0 0 0 1.108903408385661 P36009 1.0 0.17225876450538635 0.013394951820373535 0.4159554243087769 50.156701166961234 45.0 1.0 no 7313 chrXI_290186r 21596 essential YKL078W 1344 - TATCTCTTCAACATTAACAC R|454|T R|454|K K|453|N silent|AAG>AAA|K|453 DHR2 DEAH-box RNA helicase 735.0 0 0 0 0 0.028308387797805742 P36009 0.13517162203788755 0.7582671046257019 0.0 37.46957688326569 30.0 1.0 no 7314 chrXI_290248r 21597 essential YKL078W 1406 - TTACTATAGCTTCCTTTCCA V|475|L V|475|I DHR2 DEAH-box RNA helicase 735.0 0 0 0 0 0.02717154395001424 P36009 0.3417922854423523 0.21602337062358856 49.368349615500854 35.0 1.0 no 7315 chrXI_290260 21598 essential YKL078W 1415 + AGCTATAGTAATGGGGCTTC A|473|G A|473|V DHR2 DEAH-box RNA helicase 735.0 0 0 0 0 -0.1164307418627743 P36009 0.20994050800800326 0.038422301411628716 48.27543876679516 45.0 1.0 no 7316 chrXI_290276 21600 essential YKL078W 1431 + CTTCAGGAACTTTATGAATT Q|479|E Q|479|* DHR2 DEAH-box RNA helicase 735.0 0 0 0 0 0.5641240642762526 P36009 0.2689534723758697 38.03127851166681 30.0 1.0 no 7317 chrXI_290354r 21601 essential YKL078W 1512 - CTACTTAAATGCGGTTGTAG S|510|T S|510|N DHR2 DEAH-box RNA helicase 735.0 0 0 0 0 -0.023739584554058918 P36009 0.0274838674813509 0.01207304559648037 41.591274394417326 40.0 1.0 no 7318 chrXI_290391r 21602 essential YKL078W 1549 - ACTCAAACATCCGACTTCAC L|522|F silent|TTG>TTA|L|522 S|523|T S|523|N DHR2 DEAH-box RNA helicase 735.0 0 0 0 0 -0.03163192087019372 P36009 0.0671583041548729 0.599138081073761 0.5130061507225037 45.01225547364192 45.0 1.0 no 7319 chrXI_290425 21603 essential YKL078W 1580 + TATCGTCTCTTGCCTTAGTG I|528|M silent|ATC>ATT|I|528 silent|GTC>GTG|V|529 silent|GTC>GTT|V|529 DHR2 DEAH-box RNA helicase 735.0 0 0 0 0 0.6647652099681464 P36009 0.008485859259963036 51.26714251280606 45.0 1.0 no 7320 chrXI_290465r 21604 essential YKL078W 1623 - TCATCTCTTTCTTCTGGTGA E|548|Q E|548|K D|547|H D|547|N DHR2 DEAH-box RNA helicase 735.0 0 0 0 0 0.14753499784241 P36009 0.3506563305854797 0.18808943033218384 0.030756212770938873 0.28186750411987305 50.27826587326979 40.0 1.0 no 7321 chrXI_289472 21605 essential YKL078W 627 + GTGCTTACAGATTTGATATT L|211|V L|211|F DHR2 DEAH-box RNA helicase 735.0 0 0 0 0 -0.9567817562999366 P36009 0.4701338112354279 0.3498448431491852 41.23237830431089 30.0 1.0 no 7322 chrXI_326655r 21606 essential YKL060C 810 + ACTGTCCAAGAATTCCACAC T|271|S T|271|I silent|GTC>GTG|V|272 silent|GTC>GTT|V|272 FBA1 Fructose-1,6-Bisphosphate Aldolase 359.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.285801317890253 P14540 0.9491789937019348 0.9472420215606691 0.7312386631965637 0.03360135108232498 46.908118617039975 45.0 0.0 no 7323 chrXI_326805r 21608 essential YKL060C 660 + GCTGCTTTCGGTAACTGTCA A|221|G A|221|V A|222|G A|222|V FBA1 Fructose-1,6-Bisphosphate Aldolase 359.0 0 0 0 0 -0.0917536442811096 P14540 0.9484469890594482 0.9504740238189696 0.9484469890594482 0.9504740238189696 0.031031992286443714 0.028413010761141774 0.5738877654075623 0.03552818298339844 1.5779999494552612 0.6051999926567078 0.4025999903678894 -0.12999999523162842 53.083734071028395 50.0 0.0 no 7324 chrXI_326863r 21609 essential YKL060C 602 + ACAAGTTTACAACGTCTACA Q|202|E Q|202|* FBA1 Fructose-1,6-Bisphosphate Aldolase 359.0 0 1 0 0 0.2721045171219313 P14540 0.9590039849281312 0.32944756746292114 40.58766403859346 35.0 0.0 no 7325 chrXI_326930 21610 essential YKL060C 538 - AACACCATCTTCTTCACCAC V|186|L V|186|I G|185|A G|185|D FBA1 Fructose-1,6-Bisphosphate Aldolase 359.0 0 0 0 0 -0.4962898855352009 P14540 0.9539830088615416 0.9574310183525084 0.9499930143356324 0.9446240067481996 0.016711492091417313 0.3389991819858551 0.0 0.0 -0.4564000070095062 -0.38479998707771296 49.465210165613364 45.0 0.0 no 7326 chrXI_326969 21611 essential YKL060C 499 - TTCTAACCATTGGTCCATAG E|173|Q E|173|K W|171|C W|171|* FBA1 Fructose-1,6-Bisphosphate Aldolase 359.0 0 1 0 0 -3.902413529496293 P14540 0.956179976463318 0.9475290179252625 0.8858469724655151 0.0 0.0 0.17435362935066226 46.63505641208815 40.0 0.0 yes 7327 chrXI_327047 21614 essential YKL060C 421 - AGACAAATCCAACATGTGGG L|146|F silent|TTG>TTA|L|146 FBA1 Fructose-1,6-Bisphosphate Aldolase 359.0 0 1 0 0 0.04707326131472359 P14540 0.9587849974632264 0.16039061546325686 -0.7264000177383423 43.003538754161006 45.0 0.0 no 7328 chrXI_327044 21616 essential YKL060C 424 - TTCAGACAAATCCAACATGT E|148|Q E|148|K L|146|F silent|TTG>TTA|L|146 FBA1 Fructose-1,6-Bisphosphate Aldolase 359.0 0 1 0 0 0.0032664095632963237 P14540 0.956179976463318 0.9475290179252625 0.9587849974632264 0.2299909144639969 0.341121107339859 0.16039061546325686 -0.13420000672340393 -0.2754000127315521 -0.7264000177383423 40.86143249849772 35.0 0.0 no 7329 chrXI_327114 21618 essential YKL060C 354 - TCCAACATACCATCGAACCA L|124|F silent|TTG>TTA|L|124 E|125|Q E|125|K FBA1 Fructose-1,6-Bisphosphate Aldolase 359.0 0 0 0 0 -0.024439569784621057 P14540 0.9587849974632264 0.956179976463318 0.9475290179252625 0.01171958725899458 0.4549374878406525 0.7275773882865906 3.3787999153137207 47.736443126831595 45.0 0.0 no 7330 chrXI_327136 21620 essential YKL060C 332 - GCAACAACTTCTTGGCACAG L|117|F silent|TTG>TTA|L|117 L|116|F silent|TTG>TTA|L|116 FBA1 Fructose-1,6-Bisphosphate Aldolase 359.0 0 1 0 0 0.396106933229413 P14540 0.9587849974632264 0.9587849974632264 0.007444479968398809 0.6279003620147705 -1.0951999425888062 0.25180000066757197 47.60909792378943 50.0 0.0 no 7331 chrXI_327231r 21625 essential YKL060C 234 + GGTCAAAATGCTTCCATCAA Q|80|E Q|80|* FBA1 Fructose-1,6-Bisphosphate Aldolase 359.0 0 1 0 0 -0.047340355020332056 P14540 0.9590039849281312 0.0469353161752224 44.51184973731284 40.0 0.0 no 7332 chrXI_327267r 21626 essential YKL060C 198 + GCTGCTTACTTCGCTGGTAA A|67|G A|67|V A|68|G A|68|V FBA1 Fructose-1,6-Bisphosphate Aldolase 359.0 0 1 0 0 0.8661858710809242 P14540 0.9484469890594482 0.9504740238189696 0.9484469890594482 0.9504740238189696 0.06817856431007385 0.005312071181833744 0.2367103546857834 0.15194059908390045 -4.5004000663757315 9.744199752807617 0.6773999929428101 2.0216000080108643 53.020401629613104 50.0 0.0 no 7333 chrXI_327268r 21627 essential YKL060C 197 + TGCTGCTTACTTCGCTGGTA A|67|G A|67|V A|68|G A|68|V FBA1 Fructose-1,6-Bisphosphate Aldolase 359.0 0 1 0 0 0.8585453182653032 P14540 0.9484469890594482 0.9504740238189696 0.9484469890594482 0.9504740238189696 0.06817856431007385 0.005312071181833744 0.2367103546857834 0.15194059908390045 -4.5004000663757315 9.744199752807617 0.6773999929428101 2.0216000080108643 54.765674710913906 50.0 0.0 no 7334 chrXI_327294r 21628 essential YKL060C 171 + ATCATTTTGCAAACCTCTAA I|58|M silent|ATC>ATT|I|58 FBA1 Fructose-1,6-Bisphosphate Aldolase 359.0 0 1 0 0 0.2619921788039882 P14540 0.9598389863967896 0.0700463131070137 41.21851237349443 30.0 0.0 no 7335 chrXI_327406r 21630 essential YKL060C 59 + CAACTTATTCACTTACGCTA N|21|K silent|AAC>AAT|N|21 FBA1 Fructose-1,6-Bisphosphate Aldolase 359.0 0 1 0 0 -0.25652659562865954 P14540 0.9439849853515624 1.0 42.196748570472714 35.0 0.0 no 7336 chrXI_328550 21632 essential YKL059C 874 - CCTCAAAAGACCACCTGTCA L|297|F silent|TTG>TTA|L|297 R|298|T R|298|K MPE1 Mutant PCF11 Extragenic suppressor 441.0 0 0 0 0 0.5802394038888308 P35728 0.9867290258407592 0.9640290141105652 0.9823979735374452 0.1893218159675598 0.09917587786912918 1.0 49.985794830213024 50.0 0.0 no 7337 chrXI_328551 21634 essential YKL059C 873 - CTCAAAAGACCACCTGTCAA L|297|F silent|TTG>TTA|L|297 MPE1 Mutant PCF11 Extragenic suppressor 441.0 0 0 0 0 -0.2162742513337688 P35728 0.9867290258407592 0.1893218159675598 45.012721753114825 45.0 0.0 no 7338 chrXI_328731 21636 essential YKL059C 693 - TTTCGCTGAGCCATCTCTTC R|237|P R|237|Q Q|236|H silent|CAG>CAA|Q|236 MPE1 Mutant PCF11 Extragenic suppressor 441.0 0 0 0 0 0.014892026112444725 P35728 0.9462770223617554 0.9782379865646362 0.985951006412506 0.28153276443481445 0.5919881463050842 0.12189945578575136 54.82377322622756 50.0 0.0 no 7339 chrXI_328890 21642 essential YKL059C 534 - CAACGATAGCACATATAACC R|184|P R|184|H MPE1 Mutant PCF11 Extragenic suppressor 441.0 0 0 0 0 -0.11477445545007416 P35728 0.8819800019264221 0.9198700189590454 0.0 0.0 40.25641628587607 40.0 0.0 no 7340 chrXI_328896 21643 essential YKL059C 528 - TAGCACATATAACCTGGTGG C|182|S C|182|Y M|181|I M|181|I MPE1 Mutant PCF11 Extragenic suppressor 441.0 0 0 0 0 0.4493659522865644 P35728 0.9846540093421936 0.9674050211906432 0.9756749868392944 0.9756749868392944 0.0 0.0 1.0 1.0 46.21379552445274 45.0 0.0 no 7341 chrXI_329064r 21647 essential YKL059C 357 + ACAACCACTGCTAATGTTAG T|120|R T|120|I T|121|S T|121|I MPE1 Mutant PCF11 Extragenic suppressor 441.0 0 0 0 0 -0.17950855234763916 P35728 0.9528260231018066 0.9646379947662354 0.9665899872779846 0.9646379947662354 0.12824639678001404 0.13022595643997192 0.9392005801200868 0.20886707305908206 43.06546872612796 40.0 0.0 no 7342 chrXI_329097 21650 essential YKL059C 327 - TGTCTCTTTTGCAACACTCT R|115|T R|115|K K|114|N silent|AAG>AAA|K|114 MPE1 Mutant PCF11 Extragenic suppressor 441.0 0 0 0 0 -0.4739021332943624 P35728 0.955632984638214 0.9748079776763916 0.95727801322937 0.6189916729927063 0.9987890124320984 0.5126572847366333 48.63317698700121 40.0 0.0 no 7343 chrXI_329171 21651 essential YKL059C 253 - CCCTTTAAGTCGACTGTGTA G|91|R G|91|R G|91|A G|91|E MPE1 Mutant PCF11 Extragenic suppressor 441.0 0 0 0 0 -0.5253614206940452 P35728 0.9477360248565674 0.9477360248565674 0.9656509757041932 0.9509360194206238 0.40377530455589294 0.40377530455589294 1.0 0.36565062403678894 49.899956081981145 45.0 0.0 no 7344 chrXI_329171r 21652 essential YKL059C 250 + CCGTACACAGTCGACTTAAA silent|TCC>TCG|S|84 silent|TCC>TCT|S|84 H|86|D H|86|Y MPE1 Mutant PCF11 Extragenic suppressor 441.0 0 0 0 0 0.2555526984284009 P35728 0.9762660264968872 0.9764170050621032 0.8235588073730469 0.4292785227298737 44.7173586374995 45.0 0.0 no 7345 chrXI_328501r 21653 essential YKL059C 920 + TAACATAGATTTCTCAAAAG N|308|K silent|AAC>AAT|N|308 MPE1 Mutant PCF11 Extragenic suppressor 441.0 0 0 0 0 0.1837276636453912 P35728 0.96908301115036 0.4525096118450165 31.438612635108882 25.0 0.0 no 7346 chrXI_329172r 21654 essential YKL059C 249 + TCCGTACACAGTCGACTTAA silent|TCC>TCG|S|84 silent|TCC>TCT|S|84 S|84|C S|84|F MPE1 Mutant PCF11 Extragenic suppressor 441.0 0 0 0 1 -0.238664076134223 P35728 0.9634199738502502 0.9436050057411194 0.02078850567340851 0.02464979887008667 47.12585284510738 45.0 0.0 no 7347 chrXI_329223 21656 essential YKL059C 201 - ACTATGACACTAGTAGATCT V|74|L V|74|I MPE1 Mutant PCF11 Extragenic suppressor 441.0 0 0 0 0 -0.36457429660500096 P35728 0.9693499803543092 0.9770190119743348 0.20498768985271454 0.27887654304504395 41.53808748145127 35.0 0.0 no 7348 chrXI_330204 21660 essential YKL058W 38 + TACTATAGGGAATAGTTTGG T|14|S T|14|I TOA2 122.0 0 0 0 0 0.2508659205462672 P32774 0.9059399962425232 0.789717972278595 0.8609564304351807 0.0903276652097702 0.3573000133037567 -0.29914000630378723 39.196223751651814 35.0 1.0 no 7349 chrXI_330332r 21661 essential YKL058W 169 - TTTCACAGTCAATTTAGATT silent|GTG>GTC|V|62 silent|GTG>GTA|V|62 V|62|L V|62|M TOA2 122.0 0 0 0 0 -0.21845007408817388 P32774 0.9487950205802916 0.9145609736442566 0.40226584672927856 0.046507857739925385 0.1706800013780594 -0.25707998871803284 -1.0983400344848633 -1.418779969215393 38.383099411335074 25.0 1.0 no 7350 chrXI_330437 21664 essential YKL058W 271 + ACCGCGACGCCTCCCAGAAC R|92|G R|92|C H|91|Q silent|CAC>CAT|H|91 TOA2 122.0 0 1 0 0 -0.7502488102283982 P32774 0.9097800254821776 0.7914500236511229 0.991912007331848 0.03476661443710327 0.004466158337891103 0.44939324259758 -0.24568000435829165 59.4539045919073 70.0 1.0 no 7351 chrXI_337168 21665 high_effect YKL054C 1593 - CCTTGTGAATCAAACATACC invalid seq invalid seq invalid seq invalid seq DEF1 RNAPII DEgradation Factor 738.0 0 0 0 0 0.04500893304272319 P35732 42.28357163493683 40.0 0.0 no 7352 chrXI_337186r 21666 high_effect YKL054C 1572 + TTTCCTGGATATTCTTATCC invalid seq invalid seq invalid seq invalid seq DEF1 RNAPII DEgradation Factor 738.0 0 0 0 0 -0.3853776778208131 P35732 47.12438892873894 35.0 0.0 no 7353 chrXI_337483 21669 high_effect YKL054C 1278 - TGCTGTTGTAGTTGTTGTTG invalid seq invalid seq invalid seq invalid seq DEF1 RNAPII DEgradation Factor 738.0 0 0 0 0 -0.12795100360285638 P35732 48.25937395936762 40.0 0.0 no 7354 chrXI_337798r 21672 high_effect YKL054C 933 + GACAGAGTCCCTGAAGTGGA invalid seq invalid seq invalid seq invalid seq DEF1 RNAPII DEgradation Factor 738.0 0 0 0 0 -0.11788202012700645 P35732 52.56352990848336 55.00000000000001 0.0 no 7355 chrXI_337789 21673 high_effect YKL054C 945 - ACTTCTTCTCCGTCCACTTC invalid seq invalid seq invalid seq invalid seq DEF1 RNAPII DEgradation Factor 738.0 0 0 0 0 -0.6932629857000849 P35732 56.45344082657277 50.0 0.0 no 7356 chrXI_337895 21675 high_effect YKL054C 839 - CTTCACTAGCTTCAGACTTT invalid seq invalid seq invalid seq invalid seq DEF1 RNAPII DEgradation Factor 738.0 0 0 0 0 0.8174786661836411 P35732 47.68545708315668 40.0 0.0 no 7357 chrXI_338017 21677 high_effect YKL054C 717 - GCAGCCCACGACATTTTCTT invalid seq invalid seq invalid seq invalid seq DEF1 RNAPII DEgradation Factor 738.0 0 0 0 0 0.027217666244766514 P35732 55.04343321723098 50.0 0.0 no 7358 chrXI_337978 21678 high_effect YKL054C 756 - TCGGTCTTTTTAACAGCCTT invalid seq invalid seq invalid seq invalid seq DEF1 RNAPII DEgradation Factor 738.0 0 0 0 0 0.18220879954143326 P35732 49.56170177928101 40.0 0.0 no 7359 chrXI_338021r 21679 high_effect YKL054C 710 + ACAACCAAAGAAAATGTCGT invalid seq invalid seq invalid seq invalid seq DEF1 RNAPII DEgradation Factor 738.0 0 0 0 0 0.15010946125773122 P35732 37.15139533428658 35.0 0.0 no 7360 chrXI_338310r 21682 high_effect YKL054C 421 + AACATGTTAATCTCGACAAG invalid seq invalid seq invalid seq invalid seq DEF1 RNAPII DEgradation Factor 738.0 0 0 0 0 0.3958467662435571 P35732 37.16669174828883 35.0 0.0 no 7361 chrXI_338311r 21683 high_effect YKL054C 420 + AAACATGTTAATCTCGACAA invalid seq invalid seq invalid seq invalid seq DEF1 RNAPII DEgradation Factor 738.0 0 0 0 0 0.4687391567038846 P35732 35.944838147881796 30.0 0.0 no 7362 chrXI_338316 21684 high_effect YKL054C 418 - GTCGAGATTAACATGTTTCC invalid seq invalid seq invalid seq invalid seq DEF1 RNAPII DEgradation Factor 738.0 0 0 0 0 0.9474261181826272 P35732 44.24782515550703 40.0 0.0 no 7363 chrXI_338633 21687 high_effect YKL054C 101 - AATCATCACTCGTCCAGTCA invalid seq invalid seq invalid seq invalid seq DEF1 RNAPII DEgradation Factor 738.0 0 0 0 0 -3.170965140878176 P35732 50.47743037404321 45.0 0.0 yes 7364 chrXI_338674 21688 high_effect YKL054C 60 - TCTATTTTGGACTTTAGCGC invalid seq invalid seq invalid seq invalid seq DEF1 RNAPII DEgradation Factor 738.0 0 0 0 0 0.3408774000366763 P35732 46.742173425641106 40.0 0.0 no 7365 chrXI_338661 21689 high_effect YKL054C 73 - TTCTGTAAGCGTATCTATTT invalid seq invalid seq invalid seq invalid seq DEF1 RNAPII DEgradation Factor 738.0 0 0 0 0 -0.6513634408904414 P35732 42.324397570697435 30.0 0.0 no 7366 chrXI_338646r 21690 high_effect YKL054C 85 + TTACAGAATTGTTCCCTGAC invalid seq invalid seq invalid seq invalid seq DEF1 RNAPII DEgradation Factor 738.0 0 0 0 0 0.2632497597697865 P35732 45.61416796771596 40.0 0.0 no 7367 chrXI_339876 21691 essential YKL052C 651 - CGCATTTTATTGGGCACAAT M|223|I M|223|I ASK1 Associated with Spindles and Kinetochores 292.0 0 0 0 0 0.665586299533832 P35734 0.3384433090686798 0.3384433090686798 45.81116851240762 40.0 0.0 no 7368 chrXI_339924r 21694 essential YKL052C 600 + CTACTTTTGCAGCAGCAGTA L|202|V L|202|F ASK1 Associated with Spindles and Kinetochores 292.0 0 1 0 0 -0.8532759115103774 P35734 0.027995295822620392 0.02603830024600029 51.000698684526746 45.0 0.0 no 7369 chrXI_340108r 21700 essential YKL052C 416 + CACAGCGAATATAACATCCA T|140|R T|140|I A|141|G A|141|V ASK1 Associated with Spindles and Kinetochores 292.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.08392429398291368 P35734 0.05976644158363342 0.09238489717245102 0.05832090973854065 0.05896763876080512 42.41164636242695 40.0 0.0 no 7370 chrXI_340174r 21703 essential YKL052C 350 + TTCAGCTGTACATGTCAACC S|118|* S|118|L A|119|G A|119|V ASK1 Associated with Spindles and Kinetochores 292.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.3507025347622841 P35734 0.09135708957910538 0.4066994786262512 0.3109055459499359 48.77032960911571 45.0 0.0 no 7371 chrXI_340229 21707 essential YKL052C 298 - CTGCCTACTCGCCTCTTCAG R|105|S silent|AGG>AGA|R|105 R|105|T R|105|K ASK1 Associated with Spindles and Kinetochores 292.0 0 1 0 0 0.9420593860632532 P35734 0.4229413568973541 0.4127520918846129 1.0 59.124157339499 60.0 0.0 no 7372 chrXI_340355 21713 essential YKL052C 172 - AAACATAGTCCCCAGCCATT M|63|I M|63|I ASK1 Associated with Spindles and Kinetochores 292.0 0 0 0 0 0.4651527944757217 P35734 0.0 0.0 52.39008259243121 45.0 0.0 no 7373 chrXI_340417r 21716 essential YKL052C 107 + CCAGGACATCATCCCACACG Q|37|E Q|37|* D|38|E silent|GAC>GAT|D|38 ASK1 Associated with Spindles and Kinetochores 292.0 0 0 0 0 -3.334721978662009 P35734 0.04960933700203896 0.2759748697280884 54.677413292803685 60.0 0.0 yes 7374 chrXI_340435r 21718 essential YKL052C 89 + CTGCTTTCATAAGATCACCC C|31|W silent|TGC>TGT|C|31 ASK1 Associated with Spindles and Kinetochores 292.0 0 1 0 0 -0.5481202277093672 P35734 0.0 48.90075294348298 45.0 0.0 no 7375 chrXI_340107r 21719 essential YKL052C 417 + ACAGCGAATATAACATCCAC T|140|R T|140|I A|141|G A|141|V ASK1 Associated with Spindles and Kinetochores 292.0 1 Series([], Name: modification, dtype: object) 0 0 0 1.3193821728343325 P35734 0.05976644158363342 0.09238489717245102 0.05832090973854065 0.05896763876080512 41.591980273638455 40.0 0.0 no 7376 chrXI_346274 21720 essential YKL049C 471 - TCTTTCACTAGCCTTGCAAA E|164|Q E|164|K silent|GTG>GTC|V|162 silent|GTG>GTA|V|162 0 0 0 0 0.4440675815860985 P36012 0.12354444712400435 0.01709831692278385 0.7092750072479248 1.0174750089645386 48.10073633062329 40.0 0.0 no 7377 chrXI_346317r 21722 essential YKL049C 425 + TCGAAAATACCAACGTTCCA R|143|G R|143|* 0 0 0 0 0.5062086912722922 P36012 0.015729986131191254 42.557497086403096 40.0 0.0 no 7378 chrXI_346445 21724 essential YKL049C 300 - GCATATGAATGAGTTCGCAC A|107|P A|107|T 0 0 0 0 -0.2859691770333493 P36012 0.3017655313014984 0.7106749415397644 44.976237876160546 45.0 0.0 no 7379 chrXI_346586 21726 essential YKL049C 159 - CGTCTTCTTTCCTCTCTTCT R|59|T R|59|K R|58|T R|58|K 0 0 0 0 0.7339179135781089 P36012 0.5341182351112366 1.0 0.4494400024414063 1.0 55.70573805663247 45.0 0.0 no 7380 chrXI_346593 21727 essential YKL049C 152 - TTTCCTCTCTTCTTGGAAAC E|57|Q E|57|K E|56|D silent|GAG>GAA|E|56 0 0 0 0 0.2500940356726118 P36012 0.30599653720855713 0.5596646070480347 0.3527049720287323 46.378396150297135 40.0 0.0 no 7381 chrXI_346653 21729 essential YKL049C 92 - CACGATCGTTAATAGATTGT R|37|P R|37|H D|36|H D|36|N 0 0 0 0 -1.9148389795835696 P36012 0.016637234017252922 0.016596587374806404 0.1016092449426651 0.4002685546875 40.050559757310225 35.0 0.0 no 7382 chrXI_353685r 21734 essential YKL045W 195 - AACGTTATTTCTCCCTGTGG silent|ACG>ACC|T|71 silent|ACG>ACA|T|71 PRI2 DNA PRImase 528.0 0 0 0 0 0.7828566460407974 P20457 50.24556974648175 45.0 1.0 no 7383 chrXI_353688r 21735 essential YKL045W 198 - TCCAACGTTATTTCTCCCTG L|72|F silent|TTG>TTA|L|72 E|73|Q E|73|K PRI2 DNA PRImase 528.0 0 0 0 0 -0.0674489364659645 P20457 0.02617020159959793 0.040021125227212906 0.03136193007230759 51.29410284566275 45.0 1.0 no 7384 chrXI_354104 21741 essential YKL045W 611 + GTTCCAATTGAATTTAAACG F|205|L silent|TTC>TTT|F|205 Q|206|E Q|206|* PRI2 DNA PRImase 528.0 0 0 0 0 -0.29442754308471675 P20457 0.6657281517982483 36.1620502779715 30.0 1.0 no 7385 chrXI_354206r 21743 essential YKL045W 716 - CGTCCTTCAAAAACACTAAA D|245|H D|245|N K|244|N silent|AAG>AAA|K|244 PRI2 DNA PRImase 528.0 0 0 0 0 0.2355612631431351 P20457 0.07777059823274612 0.2909245193004608 0.2455814480781555 37.63085750091199 35.0 1.0 no 7386 chrXI_354360 21745 essential YKL045W 867 + ATTCTAAATCATCTTTCGTC L|291|V silent|CTA>TTA|L|291 PRI2 DNA PRImase 528.0 0 0 0 0 -0.044610777705376206 P20457 0.0 39.91329595960059 30.0 1.0 no 7387 chrXI_354361 21746 essential YKL045W 868 + TTCTAAATCATCTTTCGTCG L|291|V silent|CTA>TTA|L|291 PRI2 DNA PRImase 528.0 0 0 0 0 0.069407789284685 P20457 0.0 41.33073184983243 35.0 1.0 no 7388 chrXI_353996 21749 essential YKL045W 503 + AACAAAATTTGTTCAATCAT T|169|R T|169|I PRI2 DNA PRImase 528.0 0 0 0 0 0.21069679429952548 P20457 0.5616226196289062 0.13625724613666534 32.31249470133372 20.0 1.0 no 7389 chrXI_354561 21751 essential YKL045W 1068 + CAACTGAGTCTGTTTTTGAA L|358|V silent|CTG>TTG|L|358 PRI2 DNA PRImase 528.0 0 0 0 0 1.170859612564224 P20457 0.0954398587346077 4.302659988403319 41.05854239234203 35.0 1.0 no 7390 chrXI_354605 21752 essential YKL045W 1112 + AGCGTTAAAATTTTGGTCTG A|372|G A|372|V PRI2 DNA PRImase 528.0 0 0 0 0 0.0038812100874511812 P20457 0.05751154944300652 0.029699804261326786 1.7509000301361084 0.3496600091457367 40.46456167872765 35.0 1.0 no 7391 chrXI_354681 21753 essential YKL045W 1188 + TACAGCTTCAGGCATAATTA Y|397|* silent|TAC>TAT|Y|397 S|398|R silent|AGC>AGT|S|398 PRI2 DNA PRImase 528.0 0 0 0 0 -0.756049587232764 P20457 0.0073604676872491845 -0.6248599886894226 43.55377026244304 35.0 1.0 no 7392 chrXI_358509r 21755 essential YKL042W 37 - GTCGTAAAGCCTTGAAGATT D|19|H D|19|N SPC42 Spindle Pole Component 363.0 0 0 0 0 -1.6496479687832868 P36094 0.9486550092697144 0.956179976463318 0.14460933208465576 0.59209805727005 43.76854577017645 40.0 1.0 no 7393 chrXI_358571r 21757 essential YKL042W 99 - TCATTATAGTCTCTATTCAT D|40|H D|40|N SPC42 Spindle Pole Component 363.0 0 1 0 0 0.4697472867212511 P36094 0.9486550092697144 0.956179976463318 0.08661282062530518 0.591928243637085 40.461432242884825 25.0 1.0 no 7394 chrXI_359061 21769 essential YKL042W 586 + TCCTCACAAATTATGTTATG L|197|V L|197|F silent|GTC>GTG|V|196 silent|GTC>GTT|V|196 SPC42 Spindle Pole Component 363.0 0 0 0 0 0.05504232354568732 P36094 0.9512209892272948 0.9587849974632264 0.10574031621217728 0.07391779869794846 38.93933521704604 30.0 1.0 no 7395 chrXI_359062r 21770 essential YKL042W 590 - ACCTCATAACATAATTTGTG R|203|T R|203|K R|203|S silent|AGG>AGA|R|203 SPC42 Spindle Pole Component 363.0 0 1 0 0 0.1678784205594615 P36094 0.932735025882721 0.955805003643036 0.9087679982185364 0.5696489214897156 0.8430256843566895 0.6079553961753845 38.50856295267785 30.0 1.0 no 7396 chrXI_359189r 21772 essential YKL042W 717 - GACGGATTTACCTTAACGGT silent|CCG>CCC|P|245 silent|CCG>CCA|P|245 SPC42 Spindle Pole Component 363.0 0 0 0 0 -0.0758653900504847 P36094 46.41999590781927 45.0 1.0 no 7397 chrXI_370048 21774 essential YKL035W 157 + ATTCGTTTTTCACGCTTTTC S|54|W S|54|L UGP1 UDP-glucose pyrophosphorylase 499.0 0 0 0 0 1.0508936759635097 P32861 0.9288619756698608 0.9298099875450134 0.015701981261372566 0.29936304688453674 46.51748701014748 35.0 1.0 no 7398 chrXI_370058 21775 essential YKL035W 167 + CACGCTTTTCAGGAGATATT T|57|R T|57|M L|58|V L|58|F UGP1 UDP-glucose pyrophosphorylase 499.0 0 0 0 0 -0.4622418658857701 P32861 0.9476869702339172 0.9502379894256592 0.9512209892272948 0.9587849974632264 0.7275549173355103 0.2294739633798599 0.021194607019424442 0.04445452243089676 45.40499108819245 40.0 1.0 no 7399 chrXI_370090 21777 essential YKL035W 199 + CTTCTAGAACCACCTTGGAA S|68|C S|68|F UGP1 UDP-glucose pyrophosphorylase 499.0 0 1 0 0 0.634682377672968 P32861 0.945252001285553 0.9294660091400146 0.022129451856017116 0.021815497428178787 1.6779999732971191 -0.10920000076293944 47.2210373866576 45.0 1.0 no 7400 chrXI_370091 21778 essential YKL035W 200 + TTCTAGAACCACCTTGGAAT S|68|C S|68|F UGP1 UDP-glucose pyrophosphorylase 499.0 0 1 0 0 0.3252196422448883 P32861 0.945252001285553 0.9294660091400146 0.022129451856017116 0.021815497428178787 1.6779999732971191 -0.10920000076293944 45.4874917657461 40.0 1.0 no 7401 chrXI_370099r 21779 essential YKL035W 211 - GATCTTGTCCCATTCCAAGG K|76|N silent|AAG>AAA|K|76 UGP1 UDP-glucose pyrophosphorylase 499.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.13172381476410625 P32861 0.9355990290641784 0.022215375676751137 53.31356007721747 50.0 1.0 no 7402 chrXI_370181 21781 essential YKL035W 290 + TGTCTCAAACCTTTCCAAAT silent|GTC>GTG|V|98 silent|GTC>GTT|V|98 S|99|* S|99|L UGP1 UDP-glucose pyrophosphorylase 499.0 0 0 0 0 0.7306432709725718 P32861 0.9298099875450134 0.2823290228843689 43.58768797333317 35.0 1.0 no 7403 chrXI_370195r 21782 essential YKL035W 307 - CAACTTCAAAACAGCCAATT K|108|N silent|AAG>AAA|K|108 L|107|F silent|TTG>TTA|L|107 UGP1 UDP-glucose pyrophosphorylase 499.0 0 1 0 0 0.13365005413317813 P32861 0.9355990290641784 0.9587849974632264 0.01067448314279318 0.027989421039819717 39.30384149882696 35.0 1.0 no 7404 chrXI_370414r 21784 essential YKL035W 526 - TCTGATTCTGATTCTGTTAG R|182|T R|182|K UGP1 UDP-glucose pyrophosphorylase 499.0 0 1 0 0 0.6251488628132631 P32861 0.932735025882721 0.955805003643036 0.4074231088161469 0.31944018602371216 42.68159678350429 35.0 1.0 no 7405 chrXI_370432 21785 essential YKL035W 541 + TCAGATCTTTCAATCAATCC I|181|M silent|ATC>ATT|I|181 S|183|C S|183|F UGP1 UDP-glucose pyrophosphorylase 499.0 0 1 0 0 0.9480950017845664 P32861 0.9598389863967896 0.945252001285553 0.9294660091400146 0.0041822968050837525 0.0020220864098519087 0.001041708281263709 -0.04760000109672546 42.447054558908796 35.0 1.0 no 7406 chrXI_370370 21786 essential YKL035W 479 + TTTCAACACTGACAAGGATA F|161|L silent|TTC>TTT|F|161 N|162|K silent|AAC>AAT|N|162 UGP1 UDP-glucose pyrophosphorylase 499.0 0 1 0 0 -1.1922609309809291 P32861 0.9387490153312684 0.9439849853515624 0.009872781112790108 0.06935685873031616 0.4930000007152557 39.28787658428717 35.0 1.0 no 7407 chrXI_370501 21787 essential YKL035W 610 + ACGATTCTCCACTGGATGCT Y|204|* silent|TAC>TAT|Y|204 S|206|C S|206|F UGP1 UDP-glucose pyrophosphorylase 499.0 0 0 0 0 0.5489238853576561 P32861 0.945252001285553 0.9294660091400146 0.1267467439174652 0.4067819714546204 52.50940886462178 50.0 1.0 no 7408 chrXI_370530r 21789 essential YKL035W 642 - TCAAACAAATCACCGTGACC E|221|Q E|221|K L|219|F silent|TTG>TTA|L|219 UGP1 UDP-glucose pyrophosphorylase 499.0 0 0 0 0 0.6863636635623251 P32861 0.956179976463318 0.9475290179252625 0.9587849974632264 0.33036768436431885 0.35101020336151123 0.28769928216934204 43.21798979112839 45.0 1.0 no 7409 chrXI_370582r 21790 essential YKL035W 694 - TTCTCTTCCTTGGGCAATTA E|238|Q E|238|K R|237|T R|237|K UGP1 UDP-glucose pyrophosphorylase 499.0 0 0 0 0 0.13955570574459775 P32861 0.956179976463318 0.9475290179252625 0.932735025882721 0.955805003643036 0.011544740758836271 0.008936431258916855 0.032712724059820175 1.0 50.376349447726504 40.0 1.0 no 7410 chrXI_370676 21792 essential YKL035W 785 + GACTGGTGCCGAATATATAA T|263|S T|263|I UGP1 UDP-glucose pyrophosphorylase 499.0 0 0 0 0 0.3789428742452204 P32861 0.9491789937019348 0.9472420215606691 0.8451645970344543 0.22430986166000366 42.962267870558264 40.0 1.0 no 7411 chrXI_370684r 21793 essential YKL035W 796 - AGTCAATTCCATTATATATT L|271|F silent|TTG>TTA|L|271 UGP1 UDP-glucose pyrophosphorylase 499.0 0 0 0 0 -0.6482597769315723 P32861 0.9587849974632264 0.008520809002220629 3.2809998989105225 37.70927063037874 20.0 1.0 no 7412 chrXI_370834 21796 essential YKL035W 943 + ACTTCAACACGAATAACTTA N|315|K silent|AAC>AAT|N|315 F|316|L silent|TTC>TTT|F|316 UGP1 UDP-glucose pyrophosphorylase 499.0 0 0 0 0 1.1521149076338344 P32861 0.9439849853515624 0.9387490153312684 0.1310829371213913 0.12373951077461245 0.2111999988555908 36.3456196264284 30.0 1.0 no 7413 chrXI_375493 21801 essential YKL033W 37 + TTTCATGTGTTGAACTTTCT S|14|* S|14|L TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 0.8947296007753359 P36097 0.9298099875450134 1.0 42.494042988316274 30.0 1.0 no 7414 chrXI_375545 21802 essential YKL033W 89 + TCCAAATTCATTAACGCTAT P|31|R P|31|L P|31|A P|31|S TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 0.5451090019164396 P36097 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.02586280182003975 0.017455801367759705 0.08837009966373444 0.20950572192668915 40.07659906854508 30.0 1.0 no 7415 chrXI_375546r 21803 essential YKL033W 93 - GCCAATAGCGTTAATGAATT L|37|F silent|TTG>TTA|L|37 A|38|P A|38|T TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 0.020766110208921856 P36097 0.9587849974632264 0.9573720097541808 0.9523990154266356 0.1374472677707672 0.1815546303987503 0.3271252810955048 41.79236584556003 35.0 1.0 no 7416 chrXI_375721 21804 essential YKL033W 265 + TTCATCTCTTACGGACATGT H|90|D H|90|Y L|91|V L|91|F TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 -0.2342959704529659 P36097 0.9473130106925964 0.9489949941635132 0.9512209892272948 0.9587849974632264 0.036145202815532684 0.01418386958539486 0.0 0.0 46.709582518780955 40.0 1.0 no 7417 chrXI_375790r 21806 essential YKL033W 337 - ACTGACTAAAAATGTGATTA S|119|T S|119|N V|118|L V|118|I TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 0.5177999834117171 P36097 0.9512869715690612 0.9536849856376648 0.9539830088615416 0.9574310183525084 0.3560278117656708 0.27287018299102783 0.04672776907682419 1.0 32.69120299422991 25.0 1.0 no 7418 chrXI_375846 21807 essential YKL033W 390 + TCAGACGAGTTCAAGTACGC S|131|* S|131|L D|132|E silent|GAC>GAT|D|132 TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 -2.2030632735971354 P36097 0.9298099875450134 0.9532920122146606 0.04166854172945023 1.0 46.65895086187584 50.0 1.0 yes 7419 chrXI_375892 21808 essential YKL033W 436 + TCAAATCAGTAAGATCGCAA F|146|L silent|TTC>TTT|F|146 S|148|* S|148|L TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 -0.6399731733788656 P36097 0.9387490153312684 0.9298099875450134 0.25597789883613586 0.011168204247951508 38.59791595886321 35.0 1.0 no 7420 chrXI_375945 21809 essential YKL033W 489 + CCTAATTTACTTCCCGCTCT P|164|R P|164|L TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 0.3401006409596916 P36097 0.9432820081710817 0.9430609941482544 0.5014424920082092 0.2880701720714569 53.02741725439682 45.0 1.0 no 7421 chrXI_376086 21811 essential YKL033W 630 + ATGCTTTCCTTTATTCTTCC L|212|V L|212|F TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 0.6157073778010881 P36097 0.9512209892272948 0.9587849974632264 0.06413756310939789 0.034733764827251434 50.27852250568026 35.0 1.0 no 7422 chrXI_376125 21812 essential YKL033W 669 + GCTAAGATACTTACTAAACC A|224|G A|224|V TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 0.0579845270167893 P36097 0.9484469890594482 0.9504740238189696 0.11140112578868866 0.4136632680892944 38.588930900183186 35.0 1.0 no 7423 chrXI_376145 21815 essential YKL033W 689 + AGGCCGTCAAATACATTATA silent|GGC>GGG|G|231 silent|GGC>GGT|G|231 R|232|G R|232|C TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 0.1708002879782174 P36097 0.8994590044021606 0.8926740288734436 0.11896025389432907 0.06476199626922607 42.65623158707609 35.0 1.0 no 7424 chrXI_376148r 21816 essential YKL033W 695 - ACACCTTATAATGTATTTGA V|238|L V|238|M silent|GTG>GTC|V|238 silent|GTG>GTA|V|238 TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 -0.22057194830472715 P36097 0.9539830088615416 0.9587630033493042 0.05482728406786919 0.010541296564042568 38.527998395464856 25.0 1.0 no 7425 chrXI_376299 21817 essential YKL033W 843 + AATCAATCATTTATGTTTAA Q|283|E Q|283|* TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 0.4989360638185274 P36097 0.9590039849281312 0.9688761234283448 32.01968570562832 15.0 1.0 no 7426 chrXI_376391 21818 essential YKL033W 935 + GCAAATCAATATTGCTTTGG Q|313|E Q|313|* I|314|M silent|ATC>ATT|I|314 TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 1.2242493446003309 P36097 0.9590039849281312 0.9598389863967896 0.0 0.013141208328306677 40.213043250421784 35.0 1.0 no 7427 chrXI_376537r 21819 essential YKL033W 1084 - ACGCTCCAAATGTACTAAAG E|367|D silent|GAG>GAA|E|367 R|368|P R|368|H TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 0.14434517716538392 P36097 0.94931298494339 0.9099509716033936 0.9570810198783876 0.06585761904716493 0.27775755524635315 0.5689146518707275 40.59029819589989 40.0 1.0 no 7428 chrXI_376087 21820 essential YKL033W 631 + TGCTTTCCTTTATTCTTCCG L|212|V L|212|F S|213|C S|213|F TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 0.3015516020410723 P36097 0.9512209892272948 0.9587849974632264 0.945252001285553 0.9294660091400146 0.06413756310939789 0.034733764827251434 0.0 0.0 51.26237840489853 40.0 1.0 no 7429 chrXI_376624 21822 essential YKL033W 1168 + ACAAGCTAAGTGACATTATT H|390|Q silent|CAC>CAT|H|390 L|392|V silent|CTA>TTA|L|392 TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 0.13533691547781018 P36097 0.9588389992713928 0.9512209892272948 0.6070748567581177 0.09974729269742966 38.48232465543129 30.0 1.0 no 7430 chrXI_376779r 21823 essential YKL033W 1326 - TCTTTATGATTGATCAAACT E|449|Q E|449|K TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 1.2191246875117074 P36097 0.956179976463318 0.9475290179252625 0.4554599523544312 0.5554324984550476 36.297242403751625 25.0 1.0 no 7431 chrXI_376884r 21824 essential YKL033W 1431 - GACATGTCTTCTGATAATCT M|483|I M|483|I TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 -0.7324110488012243 P36097 0.9553959965705872 0.9553959965705872 0.35736972093582153 0.35736972093582153 42.39794543485078 35.0 1.0 no 7432 chrXI_377010r 21825 essential YKL033W 1557 - GCAACTATCTTCTGCGTTCT A|526|P A|526|T V|525|L V|525|I TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 0.3866737046297959 P36097 0.9573720097541808 0.9523990154266356 0.9539830088615416 0.9574310183525084 0.067655049264431 0.7544653415679932 0.8748903870582581 0.8243218064308167 50.90784324372663 45.0 1.0 no 7433 chrXI_377177 21829 essential YKL033W 1721 + ACTTTCTCAAGACATTAGCA L|575|V L|575|F S|576|C S|576|F TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 -1.2814042471497828 P36097 0.9512209892272948 0.9587849974632264 0.945252001285553 0.9294660091400146 0.05330256745219231 0.28636449575424194 0.18010523915290833 0.7044945359230042 43.31041311103161 35.0 1.0 no 7434 chrXI_377258 21831 essential YKL033W 1802 + CTCTATTGAAACGATTTGTG S|602|C S|602|F TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 0.6535374843965187 P36097 0.945252001285553 0.9294660091400146 0.006689149886369704 0.0035273546818643813 37.983273847232965 35.0 1.0 no 7435 chrXI_377344 21834 essential YKL033W 1888 + CATCACCGTCCGAAGCCATT S|631|* S|631|L P|632|A P|632|S TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 0.18899798645702776 P36097 0.9298099875450134 0.9562489986419678 0.9498909711837769 0.007133477833122016 0.4441013038158417 1.0 54.672441773619035 55.00000000000001 1.0 no 7436 chrXI_377125r 21835 essential YKL033W 1672 - CACTTCTTCAACCATGGAAG V|564|L V|564|M E|563|Q E|563|K TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 0.13416939722474108 P36097 0.9539830088615416 0.9587630033493042 0.956179976463318 0.9475290179252625 0.12329594790935515 0.045720670372247696 0.035090506076812744 0.028173845261335376 44.641391017006704 45.0 1.0 no 7437 chrXI_377349r 21836 essential YKL033W 1896 - ACATACCTAATGGCTTCGGA V|639|L V|639|M R|637|S silent|AGG>AGA|R|637 TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 -1.0158181476543209 P36097 0.9539830088615416 0.9587630033493042 0.9087679982185364 0.8884407281875609 0.2393720746040344 0.0 48.20263530306436 45.0 1.0 no 7438 chrXI_377353r 21837 essential YKL033W 1900 - GCTCACATACCTAATGGCTT silent|GTG>GTC|V|639 silent|GTG>GTA|V|639 S|640|T S|640|N TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 -0.6830799138799566 P36097 0.9512869715690612 0.9536849856376648 0.0230976976454258 0.008752104826271534 50.30192167097533 45.0 1.0 no 7439 chrXI_377467 21840 essential YKL033W 2011 + TTTCCTCAAGATTGAATTCT S|672|C S|672|F silent|TCC>TCG|S|672 silent|TCC>TCT|S|672 TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 -0.6370983566072349 P36097 0.945252001285553 0.9294660091400146 0.009416664019227028 0.004220368340611458 41.436181668601535 30.0 1.0 no 7440 chrXI_377424r 21841 essential YKL033W 1971 - ACGTTGCTTAAGATCATGTT V|664|L V|664|I S|662|T S|662|N TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 1.3143193747525086 P36097 0.9539830088615416 0.9574310183525084 0.9512869715690612 0.9536849856376648 0.0456014983355999 0.23451633751392365 0.5885258913040161 0.6931214332580566 43.66894507143462 35.0 1.0 no 7441 chrXI_377498 21842 essential YKL033W 2042 + ACGAGTGAGCCAAATATTAA R|682|G R|682|* TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 -0.26574643202482384 P36097 0.8994590044021606 0.027847355231642727 39.79701375136653 35.0 1.0 no 7442 chrXI_377725 21844 essential YKL033W 2269 + CACAAAGTACTTTTTCGCCC Q|758|E Q|758|* TTI1 Two Tel2-Interacting protein 1038.0 0 0 0 0 0.856997699204803 P36097 0.9590039849281312 0.3197641670703888 47.932905612921495 45.0 1.0 no 7443 chrXI_385790 21845 essential YKL028W 32 + TCTTTTAAAGTTCGTCGTTA L|12|V L|12|F TFA1 Transcription Factor a, subunit 1 482.0 0 0 0 0 0.9006270508408944 P36100 0.9512209892272948 0.9587849974632264 0.0 0.0 41.217756225815656 30.0 1.0 no 7444 chrXI_386035 21854 essential YKL028W 277 + ATGCTATTGACGCAATCAAA A|94|G A|94|V TFA1 Transcription Factor a, subunit 1 482.0 0 1 0 0 -0.13039674535539425 P36100 0.9484469890594482 0.9504740238189696 0.055324196815490716 0.048185668885707855 40.3763724806841 35.0 1.0 no 7445 chrXI_386063r 21855 essential YKL028W 308 - TCAATCTTTGTACGACTTGA L|109|F silent|TTG>TTA|L|109 R|108|T R|108|K TFA1 Transcription Factor a, subunit 1 482.0 0 0 0 0 0.6270914678977245 P36100 0.9587849974632264 0.932735025882721 0.955805003643036 0.03789686411619186 0.6642847657203674 0.9948410987854004 41.928974468147935 35.0 1.0 no 7446 chrXI_386097 21858 essential YKL028W 339 + GACAAAAATTCAGAACCTAA D|114|E silent|GAC>GAT|D|114 TFA1 Transcription Factor a, subunit 1 482.0 0 0 0 0 0.1995571420187448 P36100 0.9532920122146606 1.0 33.98549547866912 30.0 1.0 no 7447 chrXI_386143r 21860 essential YKL028W 388 - AGCTTCCAATTGTGTGTACT A|136|P A|136|T E|135|Q E|135|K TFA1 Transcription Factor a, subunit 1 482.0 0 0 0 0 0.013298050417615115 P36100 0.9573720097541808 0.9523990154266356 0.956179976463318 0.9475290179252625 0.02666828036308289 0.048565324395895004 0.028937516734004017 0.02275180071592331 49.40747834871729 40.0 1.0 no 7448 chrXI_386627r 21869 essential YKL028W 872 - TACTCTGTTTATGCCATTCA S|297|T S|297|N Q|296|H silent|CAG>CAA|Q|296 TFA1 Transcription Factor a, subunit 1 482.0 0 0 0 0 0.9246263785637924 P36100 0.9512869715690612 0.9536849856376648 0.9570760130882264 0.0 0.0 0.03213205561041832 47.71791841246335 35.0 1.0 no 7449 chrXI_386649 21871 essential YKL028W 891 + ACCATCGGTAAAACTGCTCT silent|ACC>ACG|T|298 silent|ACC>ACT|T|298 T|298|S T|298|I TFA1 Transcription Factor a, subunit 1 482.0 0 0 0 0 0.3263162204642145 P36100 0.9491789937019348 0.9472420215606691 0.036523740738630295 0.006267710123211145 47.19277730883334 45.0 1.0 no 7450 chrXI_386780 21874 essential YKL028W 1022 + AACTCTGACCGAGCAAGAAA T|342|S T|342|I L|343|V silent|CTG>TTG|L|343 TFA1 Transcription Factor a, subunit 1 482.0 0 0 0 0 -0.3433711368875905 P36100 0.9491789937019348 0.9472420215606691 0.9512209892272948 0.7189772129058838 0.1868306547403336 1.0 42.66463315313342 45.0 1.0 no 7451 chrXI_386418r 21875 essential YKL028W 663 - AACATGGTGCTGCCTTTCTT M|227|I M|227|I TFA1 Transcription Factor a, subunit 1 482.0 0 0 0 0 0.12319777099643706 P36100 0.9553959965705872 0.9553959965705872 0.2646086812019348 0.2646086812019348 52.86013912403229 45.0 1.0 no 7452 chrXI_386456 21876 essential YKL028W 698 + TGCTCCATTGCCAAATCTTA A|234|G A|234|V P|235|A P|235|S TFA1 Transcription Factor a, subunit 1 482.0 0 0 0 0 0.7463545463354371 P36100 0.9484469890594482 0.9504740238189696 0.9562489986419678 0.9498909711837769 0.41648223996162415 0.29986026883125305 49.16589109947648 40.0 1.0 no 7453 chrXI_392778 21878 essential YKL024C 343 - TTCAACGATGTCTCTTTCAA E|121|Q E|121|K V|120|L V|120|I URA6 URAcil requiring 204.0 0 0 0 0 -0.4383469697982496 P15700 1.0257400274276731 0.9999549984931946 0.924584984779358 0.9912469983100892 0.4635443985462189 0.7960835099220276 0.2214856743812561 0.5467085838317871 -0.5424200296401978 -0.916819989681244 1.87608003616333 3.826760053634644 0.4939599931240082 1.1601999998092651 42.57481745550484 35.0 0.0 no 7454 chrXI_392729 21879 essential YKL024C 392 - TCTCTAACATGATATCTTCA E|137|Q E|137|K E|137|D silent|GAG>GAA|E|137 URA6 URAcil requiring 204.0 0 0 0 0 0.5502805975230253 P15700 1.018679976463318 1.0003399848937988 0.992473006248474 0.5074551105499268 1.0 0.30883878469467163 0.09177999943494797 -0.2165399938821793 0.443120002746582 40.356104714459384 30.0 0.0 no 7455 chrXI_392820r 21882 essential YKL024C 298 + TCTTAATTGACGGATTTCCT F|100|L silent|TTC>TTT|F|100 URA6 URAcil requiring 204.0 0 1 0 0 1.1389587232472778 P15700 0.8297290205955505 0.004747457802295685 1.2682199478149414 44.138414279616605 35.0 0.0 no 7456 chrXI_392924r 21884 essential YKL024C 194 + GATCAAGAACTGCATCAAAG I|66|M silent|ATC>ATT|I|66 URA6 URAcil requiring 204.0 0 1 0 0 -0.3651119394039215 P15700 0.7001410126686096 0.0023746169172227387 0.6709399819374084 0.7564200162887573 37.90082113361189 40.0 0.0 no 7457 chrXI_392952r 21885 essential YKL024C 166 + GCAGAGCAGGTTCCCAATAT silent|GGC>GGG|G|56 silent|GGC>GGT|G|56 A|58|G A|58|V URA6 URAcil requiring 204.0 0 0 0 1 -0.6273959548316614 P15700 1.0363199710845947 1.024500012397766 0.14333470165729525 0.10443401336669922 0.2939999997615814 0.01926000043749809 0.313400000333786 0.16245999932289126 53.7052522171312 50.0 0.0 no 7458 chrXI_392998r 21889 essential YKL024C 120 + TCATTTGTCCATTTGTCAGC S|41|* S|41|L URA6 URAcil requiring 204.0 0 0 0 0 0.9705700159424046 P15700 0.9475190043449402 0.003524364437907934 0.0936800017952919 50.20006651057764 40.0 0.0 no 7459 chrXI_393070r 21894 essential YKL024C 48 + TCCGTGATCTTCGTTCTAGG silent|TCC>TCG|S|17 silent|TCC>TCT|S|17 S|17|C S|17|F URA6 URAcil requiring 204.0 0 0 0 0 -0.011497500621468535 P15700 0.7314249873161316 0.8808630108833313 0.01040157489478588 0.010539207607507706 -1.1779799461364746 -1.4700599908828735 51.973073313185814 50.0 0.0 no 7460 chrXI_395376r 21897 essential YKL022C 1850 + AGCAGAATCGTATTTTGTTC A|618|G A|618|V CDC16 Cell Division Cycle 840.0 0 0 0 0 0.4713728356332918 P09798 0.9484469890594482 0.9504740238189696 0.019795814529061317 0.00618645129725337 42.64722952383585 35.0 0.0 no 7461 chrXI_395426 21898 essential YKL022C 1803 - TGCATCCCGAGAAACAGTTT M|607|I M|607|I silent|GGG>GGC|G|606 silent|GGG>GGA|G|606 CDC16 Cell Division Cycle 840.0 0 0 0 0 -0.3219747238529337 P09798 0.9553959965705872 0.9553959965705872 0.0 0.0 48.13165275690466 45.0 0.0 no 7462 chrXI_395431r 21899 essential YKL022C 1795 + ACTTACCAAAACTGTTTCTC H|599|Q silent|CAC>CAT|H|599 P|601|A P|601|S CDC16 Cell Division Cycle 840.0 0 0 0 0 -0.341791724387986 P09798 0.9588389992713928 0.9562489986419678 0.9498909711837769 0.005991206504404546 0.0 0.0 41.402071055232504 35.0 0.0 no 7463 chrXI_395513r 21900 essential YKL022C 1713 + GCACACACGTATGCCCTAGA H|573|D H|573|Y A|572|G A|572|V CDC16 Cell Division Cycle 840.0 0 0 0 0 -0.637468414646401 P09798 0.9473130106925964 0.9489949941635132 0.9484469890594482 0.9504740238189696 0.0 0.0 0.020363474264740944 0.00636248243972659 54.78081507717695 55.00000000000001 0.0 no 7464 chrXI_395616r 21903 essential YKL022C 1610 + TGCGACCTATTATATGAGCT A|538|G A|538|V T|539|S T|539|I CDC16 Cell Division Cycle 840.0 0 0 0 0 -1.0218456501940152 P09798 0.9484469890594482 0.9504740238189696 0.9491789937019348 0.9472420215606691 1.0 0.019272265955805782 0.2887173593044281 0.31412288546562195 46.68675290257414 40.0 0.0 no 7465 chrXI_395646 21904 essential YKL022C 1583 - ACCATGTTATCGCAGACTTC W|534|S W|534|* W|534|C W|534|* CDC16 Cell Division Cycle 840.0 0 0 0 0 -0.5505930033485454 P09798 0.8858469724655151 0.8858469724655151 0.0017922590486705305 0.001346925040706992 49.05599213174759 45.0 0.0 no 7466 chrXI_395676r 21906 essential YKL022C 1550 + CCTTCTGTCGCATCGATTAG L|518|V L|518|F L|519|V silent|CTG>TTG|L|519 CDC16 Cell Division Cycle 840.0 0 0 0 0 -0.5318300548188116 P09798 0.9512209892272948 0.9587849974632264 0.9512209892272948 0.02548685111105442 0.024278614670038223 0.6899127364158629 50.747050877818076 50.0 0.0 no 7467 chrXI_395881 21907 essential YKL022C 1348 - ATCTTTCGCTAAAATCTCAT D|456|H D|456|N silent|GCG>GCC|A|454 silent|GCG>GCA|A|454 CDC16 Cell Division Cycle 840.0 0 0 0 0 -0.29123024518894713 P09798 0.9486550092697144 0.956179976463318 0.3315698206424713 0.11006705462932588 40.345317656126106 30.0 0.0 no 7468 chrXI_395919r 21909 essential YKL022C 1307 + CCTATCTAAATACATCAACA L|437|V silent|CTA>TTA|L|437 S|438|C S|438|F CDC16 Cell Division Cycle 840.0 0 0 0 0 -1.0756637124930502 P09798 0.9512209892272948 0.945252001285553 0.9294660091400146 0.09715688228607178 0.0033525018952786922 0.0025214848574250932 37.76709255826796 30.0 0.0 no 7469 chrXI_395981r 21910 essential YKL022C 1245 + TCTTTGGATTTCAAAGAATT S|416|C S|416|F CDC16 Cell Division Cycle 840.0 0 0 0 0 0.7866599333253321 P09798 0.945252001285553 0.9294660091400146 0.10099656134843826 0.02003055065870285 36.133493364208505 25.0 0.0 no 7470 chrXI_396008 21911 essential YKL022C 1221 - AACAGGTCCCATTCCTCTTG silent|CTG>CTC|L|413 silent|CTG>CTA|L|413 CDC16 Cell Division Cycle 840.0 0 0 0 0 0.2855594537679748 P09798 54.40604620731607 50.0 0.0 no 7471 chrXI_396018 21912 essential YKL022C 1211 - ATTCCTCTTGTGGAGTTAAC E|410|Q E|410|K E|409|D silent|GAG>GAA|E|409 CDC16 Cell Division Cycle 840.0 0 1 0 0 -1.0933049482616524 P09798 0.956179976463318 0.9475290179252625 0.94931298494339 0.0 0.0 0.06674755364656447 46.64701786487626 40.0 0.0 no 7472 chrXI_396117r 21914 essential YKL022C 1109 + TGCACAAAATAATTTTAACA A|371|G A|371|V Q|372|E Q|372|* CDC16 Cell Division Cycle 840.0 0 0 0 0 0.6708223548925772 P09798 0.9484469890594482 0.9504740238189696 0.9590039849281312 0.26259279251098633 0.1669796109199524 0.020143060013651848 31.460232461276522 20.0 0.0 no 7473 chrXI_396191r 21917 essential YKL022C 1035 + ACGTCACAGCCAGTTACTGA T|346|R T|346|M S|347|* S|347|L CDC16 Cell Division Cycle 840.0 0 0 0 0 -0.6763281646245592 P09798 0.9476869702339172 0.9502379894256592 0.9298099875450134 0.5431075692176819 0.12609948217868805 0.3131951689720154 52.21535582652774 50.0 0.0 no 7474 chrXI_396227r 21918 essential YKL022C 999 + GCAAACACCATGAGCAATAA A|334|G A|334|V N|335|K silent|AAC>AAT|N|335 CDC16 Cell Division Cycle 840.0 0 0 0 0 0.1547150088688491 P09798 0.9484469890594482 0.9504740238189696 0.9439849853515624 0.4067034125328064 0.2776347100734711 0.9252899289131165 41.49956377526496 40.0 0.0 no 7475 chrXI_396342r 21920 essential YKL022C 884 + TATCCTGTGTCGATATCTGT I|296|M silent|ATC>ATT|I|296 L|297|V silent|CTG>TTG|L|297 CDC16 Cell Division Cycle 840.0 0 0 0 0 -0.25034044196829386 P09798 0.9598389863967896 0.9512209892272948 0.07831016182899475 0.4489554762840271 48.74063037160272 40.0 0.0 no 7476 chrXI_396367 21921 essential YKL022C 862 - AACGCCATCCAAGTTGTTCC V|294|L V|294|I G|293|A G|293|D CDC16 Cell Division Cycle 840.0 0 0 0 0 0.5156061954604017 P09798 0.9539830088615416 0.9574310183525084 0.9499930143356324 0.9446240067481996 0.33165571093559265 0.2076943814754486 0.7813525795936584 0.8257795572280884 52.796535711151364 50.0 0.0 no 7477 chrXI_396375r 21922 essential YKL022C 851 + ACTTATTACCAGGAACAACT L|285|V L|285|F CDC16 Cell Division Cycle 840.0 0 0 0 0 0.4986662904505251 P09798 0.9512209892272948 0.9587849974632264 0.016291508451104164 0.1506197303533554 41.3302771385774 35.0 0.0 no 7478 chrXI_396655r 21928 essential YKL022C 571 + CTGCGAATGCTAATAATGAT A|192|G A|192|V CDC16 Cell Division Cycle 840.0 0 0 0 0 -0.3667363684829996 P09798 0.9484469890594482 0.9504740238189696 0.1961221694946289 0.4093942046165466 38.74965379599979 35.0 0.0 no 7479 chrXI_396744r 21929 essential YKL022C 482 + GAGCTTACAGCGTGAATATA S|162|R silent|AGC>AGT|S|162 CDC16 Cell Division Cycle 840.0 0 0 0 0 -0.2445940892521051 P09798 0.9417110085487366 0.012278228998184204 43.48467761100665 40.0 0.0 no 7480 chrXI_396772r 21932 essential YKL022C 454 + CTACCATACCGTCCACATTA T|153|S T|153|I silent|ACC>ACG|T|153 silent|ACC>ACT|T|153 CDC16 Cell Division Cycle 840.0 0 1 0 0 0.7149632549574746 P09798 0.9491789937019348 0.9472420215606691 0.6515172719955444 0.0864727795124054 50.77789160020177 45.0 0.0 no 7481 chrXI_396855r 21934 essential YKL022C 371 + TTCTAATTCCAATTCCATTA S|125|C S|125|F CDC16 Cell Division Cycle 840.0 0 0 0 0 0.5296151509396747 P09798 0.945252001285553 0.9294660091400146 41.2910087275219 25.0 0.0 no 7482 chrXI_396917 21935 essential YKL022C 312 - GCTTGCAACTTCTGTATTAA A|111|P A|111|T L|109|F silent|TTG>TTA|L|109 CDC16 Cell Division Cycle 840.0 0 1 0 0 0.5128394924908027 P09798 0.9573720097541808 0.9523990154266356 0.9587849974632264 43.86198144628224 35.0 0.0 no 7483 chrXI_396940 21936 essential YKL022C 289 - GCTATTTGCTAACGACTGGT S|103|T S|103|N CDC16 Cell Division Cycle 840.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.5008999006736878 P09798 0.9512869715690612 0.9536849856376648 48.061566582029 45.0 0.0 no 7484 chrXI_396971 21938 essential YKL022C 258 - GCCGTATTGGTTCTGTTCCA silent|ACG>ACC|T|92 silent|ACG>ACA|T|92 A|93|P A|93|T CDC16 Cell Division Cycle 840.0 0 0 0 0 -2.133644401305117 P09798 0.9573720097541808 0.9523990154266356 57.475673730278466 50.0 0.0 yes 7485 chrXI_397080r 21939 essential YKL022C 146 + TTCACAACATAATTCTACAT S|50|* S|50|L Q|51|E Q|51|* CDC16 Cell Division Cycle 840.0 0 0 0 0 -0.22510190833753765 P09798 0.9298099875450134 0.9590039849281312 36.225822170371494 25.0 0.0 no 7486 chrXI_397140r 21940 essential YKL022C 86 + AAACTTGAAATCGTCAAACA N|30|K silent|AAC>AAT|N|30 CDC16 Cell Division Cycle 840.0 0 0 0 0 1.0614729539906418 P09798 0.9439849853515624 34.15793692908318 30.0 0.0 no 7487 chrXI_397697r 21942 essential YKL021C 1031 + CAGCCCCGCTTTTTCTTTAT S|345|R silent|AGC>AGT|S|345 P|346|A P|346|S MAK11 MAintenance of Killer 468.0 0 0 0 0 -0.17765109535746254 P20484 0.5175173282623291 0.8133327960968018 0.31119006872177124 55.92725076114789 45.0 0.0 no 7488 chrXI_396854r 21943 essential YKL022C 372 + TCTAATTCCAATTCCATTAC S|125|C S|125|F CDC16 Cell Division Cycle 840.0 0 0 0 0 0.5628197335484912 P09798 0.945252001285553 0.9294660091400146 41.471099338886795 30.0 0.0 no 7489 chrXI_397956 21944 essential YKL021C 775 - CACGGCAAAATAATCACCTT V|265|L V|265|M A|264|P A|264|T MAK11 MAintenance of Killer 468.0 0 0 0 0 -0.9244556747577226 P20484 0.04917921125888825 0.009142683818936348 0.057899776846170425 0.18058089911937714 41.97928699464626 40.0 0.0 no 7490 chrXI_398088 21945 essential YKL021C 643 - AACACTGATGGCAATTCTAT V|221|L V|221|I S|220|T S|220|N MAK11 MAintenance of Killer 468.0 0 0 0 0 -0.8914541250860929 P20484 0.02728467434644699 0.1318492293357849 0.0 0.0 41.37712682284467 35.0 0.0 no 7491 chrXI_398123r 21946 essential YKL021C 605 + CACGGCAAGGGTTAATGATG T|203|R T|203|M A|204|G A|204|V MAK11 MAintenance of Killer 468.0 0 0 0 0 0.3634544660274604 P20484 0.6331049203872681 0.06657620519399643 1.0 0.03592631220817566 44.796000582775385 50.0 0.0 no 7492 chrXI_398183 21947 essential YKL021C 548 - CTCTCCAAACCATAATTTTG R|189|T R|189|K W|188|C W|188|* MAK11 MAintenance of Killer 468.0 0 0 0 0 0.17604952018971054 P20484 0.012216046452522278 0.0713893324136734 0.002571100136265159 41.486802185783354 35.0 0.0 no 7493 chrXI_398386r 21950 essential YKL021C 342 + TCAAGAAGATACCTAGTTTC S|115|* S|115|L MAK11 MAintenance of Killer 468.0 0 0 0 0 0.4384844011140515 P20484 0.04678094759583473 40.01289173542529 35.0 0.0 no 7494 chrXI_398417 21951 essential YKL021C 314 - AACATTTAATACTCAACGAA C|111|S C|111|Y MAK11 MAintenance of Killer 468.0 0 0 0 0 -0.017194264397058682 P20484 0.6856951713562012 0.02643287181854248 33.19782002900047 25.0 0.0 no 7495 chrXI_398418 21952 essential YKL021C 313 - ACATTTAATACTCAACGAAT C|111|S C|111|Y MAK11 MAintenance of Killer 468.0 0 0 0 0 -0.3690887548929808 P20484 0.6856951713562012 0.02643287181854248 34.320242915789784 25.0 0.0 no 7496 chrXI_398482 21953 essential YKL021C 249 - GCATCATTTTCCTTTTGATT A|90|P A|90|T D|89|H D|89|N MAK11 MAintenance of Killer 468.0 0 0 0 0 0.3086798682738968 P20484 46.203775185983325 30.0 0.0 no 7497 chrXI_398483 21954 essential YKL021C 248 - CATCATTTTCCTTTTGATTT D|89|H D|89|N MAK11 MAintenance of Killer 468.0 0 0 0 0 0.3815258118805879 P20484 42.710766073081174 25.0 0.0 no 7498 chrXI_398546r 21955 essential YKL021C 182 + GAACCAATTTCGTATCATTG N|62|K silent|AAC>AAT|N|62 Q|63|E Q|63|* MAK11 MAintenance of Killer 468.0 0 0 0 0 0.4949813352077192 P20484 0.9216992259025574 0.5835757851600647 40.49291130972534 35.0 0.0 no 7499 chrXI_398591 21957 essential YKL021C 140 - TTCTACACGAATTCTTGACT R|53|T R|53|K C|52|S C|52|Y MAK11 MAintenance of Killer 468.0 0 1 0 0 -0.5527504056555221 P20484 41.71541776035213 35.0 0.0 no 7500 chrXI_398615r 21958 essential YKL021C 113 + CTCATCTCGAAAAGATCCTA S|39|* S|39|L S|40|C S|40|F MAK11 MAintenance of Killer 468.0 0 0 0 0 -1.4990698318149205 P20484 42.480388273122905 40.0 0.0 no 7501 chrXI_398375 21959 essential YKL021C 356 - CGTCATTGGATCCAGAAACT D|125|H D|125|N MAK11 MAintenance of Killer 468.0 0 0 0 0 -0.6722211917208029 P20484 0.0 0.0 45.695890657187874 45.0 0.0 no 7502 chrXI_402604r 21960 essential YKL019W 39 - TCCTGCAAGTCTGTCTCAAT Q|19|H silent|CAG>CAA|Q|19 D|20|H D|20|N RAM2 RAS protein and A-factor Maturation 316.0 0 0 0 0 -1.488944327600524 P29703 0.10809197276830672 0.12866362929344174 0.5172678828239441 51.09868298656284 45.0 1.0 no 7503 chrXI_402617 21961 essential YKL019W 49 + ACTTGCAGGATGAACTGTGC D|17|E silent|GAC>GAT|D|17 Q|19|E Q|19|* RAM2 RAS protein and A-factor Maturation 316.0 0 0 0 0 0.3897606404792152 P29703 1.0 1.0 48.546248140847176 50.0 1.0 no 7504 chrXI_402650r 21963 essential YKL019W 85 - CATCAACCGCTTATAATCCT L|34|F silent|TTG>TTA|L|34 silent|CGG>CGC|R|33 silent|CGG>CGA|R|33 RAM2 RAS protein and A-factor Maturation 316.0 0 0 0 0 -0.05763736208376685 P29703 0.0689244344830513 -0.12200000137090684 46.40703500608107 40.0 1.0 no 7505 chrXI_402696 21967 essential YKL019W 128 + CCTTAACGAACTGTCACCCA L|44|V L|44|F N|45|K silent|AAC>AAT|N|45 RAM2 RAS protein and A-factor Maturation 316.0 0 0 0 0 0.4857926807823195 P29703 0.2858991324901581 0.053604505956172936 0.9236725568771362 1.1480000019073486 -0.0820000022649765 50.32989823835038 50.0 1.0 no 7506 chrXI_402776 21972 essential YKL019W 208 + ACTACCGATTCAATATCGTC N|70|K silent|AAC>AAT|N|70 Y|71|* silent|TAC>TAT|Y|71 RAM2 RAS protein and A-factor Maturation 316.0 0 0 0 0 -1.2095094946789158 P29703 0.48388287425041204 43.897577223751796 40.0 1.0 no 7507 chrXI_402822 21973 essential YKL019W 254 + CACTGTCTTGTACCTGAACA T|86|S T|86|I silent|GTC>GTG|V|87 silent|GTC>GTT|V|87 RAM2 RAS protein and A-factor Maturation 316.0 0 0 0 0 1.037829757093062 P29703 47.92256174026795 45.0 1.0 no 7508 chrXI_402902r 21976 essential YKL019W 337 - CTTCAAAAGAGACTGTCTAT L|118|F silent|TTG>TTA|L|118 RAM2 RAS protein and A-factor Maturation 316.0 0 0 0 0 -0.6651421808232454 P29703 0.028023483231663704 1.795799970626831 38.62453481693893 35.0 1.0 no 7509 chrXI_402958r 21978 essential YKL019W 393 - TCAATCATCAGTTTTAAGAT D|138|H D|138|N M|136|I M|136|I RAM2 RAS protein and A-factor Maturation 316.0 0 0 0 0 0.5999217826178844 P29703 0.013477805070579052 0.04313642531633377 0.0 0.0 36.933996373380644 25.0 1.0 no 7510 chrXI_402986 21979 essential YKL019W 418 + ATTCCAAGAATTATCACGTT S|141|C S|141|F silent|TCC>TCG|S|141 silent|TCC>TCT|S|141 RAM2 RAS protein and A-factor Maturation 316.0 0 0 0 0 0.16278377142814646 P29703 0.04809505119919777 0.02910355851054192 40.50661670306732 30.0 1.0 no 7511 chrXI_403088 21983 essential YKL019W 520 + ACATTTATAACAACAGCGCA D|174|E silent|GAC>GAT|D|174 RAM2 RAS protein and A-factor Maturation 316.0 0 0 0 0 0.3117625107103926 P29703 0.0 41.070852143406746 35.0 1.0 no 7512 chrXI_403170 21986 essential YKL019W 602 + CGACGAGCTCCAGTTCATTA D|202|E silent|GAC>GAT|D|202 RAM2 RAS protein and A-factor Maturation 316.0 0 0 0 0 0.5902435291962677 P29703 1.0 50.912296791473004 50.0 1.0 no 7513 chrXI_403247 21990 essential YKL019W 679 + TCCAAGAGCTATTCCATGAT Q|228|E Q|228|* F|227|L silent|TTC>TTT|F|227 RAM2 RAS protein and A-factor Maturation 316.0 0 0 0 0 -0.5008781409945887 P29703 0.07008994370698929 0.4233014583587647 47.65689695920036 40.0 1.0 no 7514 chrXI_403257 21991 essential YKL019W 689 + ATTCCATGATAGGCTACAGT F|231|L silent|TTC>TTT|F|231 H|232|D H|232|Y RAM2 RAS protein and A-factor Maturation 316.0 0 0 0 0 -0.6880599073777416 P29703 0.9350599050521852 0.6796239018440247 0.08996310830116272 0.4722000062465668 0.03440000116825104 -0.7684000134468079 48.12222725627771 40.0 1.0 no 7515 chrXI_403260r 21992 essential YKL019W 695 - TATCCCACTGTAGCCTATCA D|238|H D|238|N W|237|C W|237|* RAM2 RAS protein and A-factor Maturation 316.0 0 0 0 0 -0.617498686854606 P29703 0.08710049092769623 0.2827827334403992 0.1769585907459259 -0.7098000049591064 54.13417927441174 45.0 1.0 no 7516 chrXI_404195 21999 essential YKL018W 93 + TCATTGAATTTCGACGATAA S|32|* S|32|L SWD2 Set1c, WD40 repeat protein 329.0 0 0 0 0 0.20037280680454966 P36104 0.002399354008957744 26.99920082092285 36.98303493410947 30.0 1.0 no 7517 chrXI_404380 22002 essential YKL018W 278 + TGACATTAAATACCTTAATC D|94|E silent|GAC>GAT|D|94 SWD2 Set1c, WD40 repeat protein 329.0 0 0 0 0 0.6650153267317486 P36104 0.007820263504981995 34.29964261933503 25.0 1.0 no 7518 chrXI_404442r 22004 essential YKL018W 343 - CATCTTCAAATCATTCACTA K|120|N silent|AAG>AAA|K|120 L|119|F silent|TTG>TTA|L|119 SWD2 Set1c, WD40 repeat protein 329.0 0 0 0 0 0.9814067206489104 P36104 0.004889882169663906 0.0031471047550439835 -1.996399998664856 39.40856390494355 30.0 1.0 no 7519 chrXI_404493 22005 essential YKL018W 391 + CGTCATACGATGAATCCGTT S|132|* S|132|L SWD2 Set1c, WD40 repeat protein 329.0 0 0 0 0 -4.127353138883635 P36104 0.002013592980802059 45.97731468290635 45.0 1.0 yes 7520 chrXI_404508r 22007 essential YKL018W 409 - CTTCAAATCCCAAAGCCTAA L|142|F silent|TTG>TTA|L|142 SWD2 Set1c, WD40 repeat protein 329.0 0 0 0 0 0.7871397886407334 P36104 0.08252622932195662 0.6567999720573425 44.768505903872956 40.0 1.0 no 7521 chrXI_404540r 22008 essential YKL018W 441 - AGACTTGGTATAATAACTTG S|153|T S|153|N SWD2 Set1c, WD40 repeat protein 329.0 0 0 0 0 -1.0167288422599052 P36104 0.9152079820632936 0.9476154446601868 35.8675712557515 30.0 1.0 no 7522 chrXI_404645 22009 essential YKL018W 543 + AATCTGAAAAAAATTCAGGA L|183|V silent|CTG>TTG|L|183 SWD2 Set1c, WD40 repeat protein 329.0 0 0 0 0 -0.8360433872957775 P36104 0.7241656184196472 4.343200206756592 30.71495515678339 25.0 1.0 no 7523 chrXI_404801 22010 essential YKL018W 699 + CAACAATTATTCGAACTAAT Q|235|E Q|235|* SWD2 Set1c, WD40 repeat protein 329.0 0 0 0 0 0.3701610675725796 P36104 1.0 1.0931999683380127 32.842305994117396 25.0 1.0 no 7524 chrXI_404836r 22012 essential YKL018W 737 - AATCTAGAAATTCTCTCATC D|252|H D|252|N SWD2 Set1c, WD40 repeat protein 329.0 0 0 0 0 -0.107929144113082 P36104 0.07126670330762863 0.473249614238739 37.12933889990643 30.0 1.0 no 7525 chrXI_412936r 22013 essential YKL014C 3955 + AATCTCACACCGCTACTTCA S|1320|C S|1320|F H|1321|D H|1321|Y URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 1.0332210232162249 P34241 0.945252001285553 0.9294660091400146 0.9473130106925964 0.9489949941635132 0.009655511938035488 0.005121298599988222 0.4928573369979858 0.06851514428853989 49.674247476712075 45.0 0.0 no 7526 chrXI_413061r 22015 essential YKL014C 3830 + CTCTTTATTCAGCATCGACC S|1278|C S|1278|F URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 0.5632310597092706 P34241 0.945252001285553 0.9294660091400146 0.19421429932117465 0.6675750017166138 49.16434587595751 45.0 0.0 no 7527 chrXI_413276r 22018 essential YKL014C 3615 + TCTCAATTAGAGGCTATTCT Q|1207|E Q|1207|* S|1206|C S|1206|F URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 -0.27808782753565914 P34241 0.9590039849281312 0.945252001285553 0.9294660091400146 0.0 0.009836696088314056 0.005210836417973042 44.190844453563564 35.0 0.0 no 7528 chrXI_413286r 22019 essential YKL014C 3605 + AATCATTAATTCTCAATTAG I|1203|M silent|ATC>ATT|I|1203 URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 0.003481745047995838 P34241 0.9598389863967896 0.0845436230301857 32.01700607801388 20.0 0.0 no 7529 chrXI_413455r 22020 essential YKL014C 3436 + ACAATAATTTTACTTATCCA H|1146|Q silent|CAC>CAT|H|1146 URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 0.007875826515639797 P34241 0.9588389992713928 0.485623300075531 36.10236434666609 20.0 0.0 no 7530 chrXI_413456r 22021 essential YKL014C 3435 + CACAATAATTTTACTTATCC H|1146|Q silent|CAC>CAT|H|1146 URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 0.17318055989895922 P34241 0.9588389992713928 0.485623300075531 36.10236434666609 25.0 0.0 no 7531 chrXI_413608 22022 essential YKL014C 3286 - GTCAAAAATCTCACTTTTCG D|1102|H D|1102|N URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 0.5913606745150021 P34241 0.9486550092697144 0.956179976463318 0.05506771430373192 0.15915513038635254 38.62298154080793 35.0 0.0 no 7532 chrXI_413647 22023 essential YKL014C 3247 - CGCAATTTCATTACCATACT A|1089|P A|1089|T URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 -0.3583821188082916 P34241 0.9573720097541808 0.9523990154266356 0.36551401019096375 0.7066566944122314 43.78112410922103 35.0 0.0 no 7533 chrXI_413759 22026 essential YKL014C 3135 - TCCTTGATCCTCCAGATACT K|1051|N silent|AAG>AAA|K|1051 D|1052|H D|1052|N URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 -0.3266477012636513 P34241 0.9355990290641784 0.9486550092697144 0.956179976463318 0.3288190960884094 0.11065466701984407 0.5728211998939514 53.210965850476846 45.0 0.0 no 7534 chrXI_413770r 22028 essential YKL014C 3121 + CATCTTTCATACCAAGTATC S|1042|C S|1042|F URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 0.6951781005850968 P34241 0.945252001285553 0.9294660091400146 0.19963380694389346 0.7134817242622375 42.636490679066014 35.0 0.0 no 7535 chrXI_413809r 22030 essential YKL014C 3082 + TACTGAAAGCTTTTTACAGA L|1029|V silent|CTG>TTG|L|1029 URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 0.6477051399606166 P34241 0.9512209892272948 0.0 38.230238844307905 30.0 0.0 no 7536 chrXI_414007 22032 essential YKL014C 2887 - GTTCAGTATATTCTTTACAA silent|CTG>CTC|L|968 silent|CTG>CTA|L|968 URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 0.11745445296717613 P34241 38.66359321871215 25.0 0.0 no 7537 chrXI_414221r 22033 essential YKL014C 2670 + ATTCAAAAAGTCGTGTTTAG Q|892|E Q|892|* URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 1.0981478308188757 P34241 0.9590039849281312 1.0 35.8306564077846 30.0 0.0 no 7538 chrXI_414249 22034 essential YKL014C 2645 - CTCGGAATTCCACTAATTGA R|888|P R|888|Q URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 -0.11321107600146113 P34241 0.9099509716033936 0.949662983417511 0.24092720448970795 0.4991070330142975 43.47433233163582 40.0 0.0 no 7539 chrXI_414387r 22035 essential YKL014C 2504 + ATTCCCAATTATCAAAGTTT F|836|L silent|TTC>TTT|F|836 P|837|A P|837|S URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 0.9455011941589296 P34241 0.9387490153312684 0.9562489986419678 0.9498909711837769 0.3984568417072296 0.7188360691070557 0.8743319511413574 40.20438238735847 25.0 0.0 no 7540 chrXI_414384 22036 essential YKL014C 2510 - TTTCCAAAACTTTGATAATT E|843|Q E|843|K L|842|F silent|TTG>TTA|L|842 URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 0.5837518567505449 P34241 0.956179976463318 0.9475290179252625 0.9587849974632264 0.6081305742263794 0.9987629055976868 0.7008100152015686 34.414981550972016 20.0 0.0 no 7541 chrXI_414436 22037 essential YKL014C 2458 - AATCTTGCCAGTTAACTCAC K|825|N silent|AAG>AAA|K|825 URB1 Unhealthy Ribosome Biogenesis 1764.0 0 1 0 0 0.18658259422260096 P34241 0.9355990290641784 0.018922856077551842 45.35239960811072 40.0 0.0 no 7542 chrXI_414504r 22041 essential YKL014C 2387 + CCTTTTTAGAGTTCAGTTAT L|797|V L|797|F URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 1.7898688333243316 P34241 0.9512209892272948 0.9587849974632264 0.6473820209503174 0.02919091656804085 44.03499757690582 30.0 0.0 no 7543 chrXI_414804 22045 essential YKL014C 2090 - GCCATTTAATTAAAAACTCT W|703|S W|703|* W|703|C W|703|* URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 0.3943772559289863 P34241 0.8858469724655151 0.8858469724655151 0.006214446388185024 0.0041976626962423325 36.05796069327073 25.0 0.0 no 7544 chrXI_414903r 22048 essential YKL014C 1988 + ACCATACAAGTACGTCGATA P|664|R P|664|L P|664|A P|664|S URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 0.14688049244753545 P34241 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 43.67349329221094 40.0 0.0 no 7545 chrXI_414902 22049 essential YKL014C 1992 - GCCATATCGACGTACTTGTA M|670|I M|670|I A|671|P A|671|T URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 -0.5602970499570925 P34241 0.9553959965705872 0.9553959965705872 0.9573720097541808 0.9523990154266356 0.3522872626781464 0.3522872626781464 0.04071484506130218 0.052609626203775406 48.893936076373386 45.0 0.0 no 7546 chrXI_415032r 22051 essential YKL014C 1859 + ATCTTTAATTTCACCAGTGA S|621|C S|621|F URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 0.10094397080567216 P34241 0.945252001285553 0.9294660091400146 0.19404803216457367 0.6229055523872375 42.63651344988409 30.0 0.0 no 7547 chrXI_415117 22053 essential YKL014C 1777 - CACGTTAGAAGCATTTTTGG V|599|L V|599|M URB1 Unhealthy Ribosome Biogenesis 1764.0 0 1 0 0 0.4549529797595003 P34241 0.9539830088615416 0.9587630033493042 0.11056098341941832 0.039054926484823234 42.697312414287246 40.0 0.0 no 7548 chrXI_415407r 22055 essential YKL014C 1484 + ATCTACTTTGAGCAATTCTT S|496|C S|496|F T|497|S T|497|I URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 -0.052142712260727885 P34241 0.945252001285553 0.9294660091400146 0.9491789937019348 0.9472420215606691 0.009778146632015705 0.005210584029555321 0.15429313480854034 0.3019560873508453 42.19544952699533 30.0 0.0 no 7549 chrXI_415498 22057 essential YKL014C 1396 - GCCTTTTTGATCATAAAATG G|472|R G|472|S G|472|A G|472|D URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 -0.2415719582701953 P34241 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 38.355987403632014 30.0 0.0 no 7550 chrXI_415499r 22058 essential YKL014C 1392 + TCCACATTTTATGATCAAAA silent|TCC>TCG|S|465 silent|TCC>TCT|S|465 S|465|C S|465|F URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 0.17635766828784 P34241 0.945252001285553 0.9294660091400146 0.022582557052373886 0.2438237965106964 36.83818231535047 25.0 0.0 no 7551 chrXI_415543 22059 essential YKL014C 1351 - CGCTAGAACTATTGATTGAC A|457|P A|457|T URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 0.1729183239368513 P34241 0.9573720097541808 0.9523990154266356 0.06378355622291565 0.2991030812263489 40.384194769426585 40.0 0.0 no 7552 chrXI_415646 22061 essential YKL014C 1248 - TCTATAACTAATGAAGTGGC E|423|Q E|423|K URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 0.4167540465985377 P34241 0.956179976463318 0.9475290179252625 0.15913623571395874 0.029430350288748738 38.00557533442782 35.0 0.0 no 7553 chrXI_415682 22062 essential YKL014C 1212 - TCAACTTTCTCCATAAATTG D|411|H D|411|N V|410|L V|410|I URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 0.13830116531291747 P34241 0.9486550092697144 0.956179976463318 0.9539830088615416 0.9574310183525084 0.02630915865302086 0.05617305263876915 0.2982246577739716 0.8317819237709045 38.64077814861554 30.0 0.0 no 7554 chrXI_415692r 22063 essential YKL014C 1199 + TCTTAAGATACCGCAATTTA L|401|V L|401|F URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 0.02510916535701724 P34241 0.9512209892272948 0.9587849974632264 0.0 0.0 40.15360851773886 30.0 0.0 no 7555 chrXI_415781r 22065 essential YKL014C 1110 + AGCATCTTTTTAACGACGAA S|371|R silent|AGC>AGT|S|371 I|372|M silent|ATC>ATT|I|372 URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 0.13396116284467893 P34241 0.9417110085487366 0.9598389863967896 0.015827657654881474 0.21141546964645386 40.62240619985579 35.0 0.0 no 7556 chrXI_415928 22069 essential YKL014C 966 - TCCACTTGGTTGACGGTTAT silent|GTG>GTC|V|328 silent|GTG>GTA|V|328 E|329|Q E|329|K URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 -0.20203409324998592 P34241 0.956179976463318 0.9475290179252625 0.11325208097696304 0.2293374389410019 50.590865569849434 45.0 0.0 no 7557 chrXI_415967r 22071 essential YKL014C 924 + TTCAAAAATTCAGTTGCTGA F|309|L silent|TTC>TTT|F|309 URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 0.3952297119639597 P34241 0.9387490153312684 0.03795788064599037 38.00889329154728 30.0 0.0 no 7558 chrXI_416226 22072 essential YKL014C 668 - CCTTATTCATGAATTTAAAT K|229|N silent|AAG>AAA|K|229 URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 -0.07244606832099522 P34241 0.9355990290641784 0.0 34.48333536315556 20.0 0.0 no 7559 chrXI_416368 22073 essential YKL014C 526 - ATCAGCAGATGAATTCCCAT D|182|H D|182|N A|181|P A|181|T URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 -1.0860972589799816 P34241 0.9486550092697144 0.956179976463318 0.9573720097541808 0.9523990154266356 0.11672111600637435 0.6153799891471863 0.2797210514545441 0.5686383843421936 47.66360087937164 40.0 0.0 no 7560 chrXI_416383r 22074 essential YKL014C 508 + GCAAGTCTGAGTTAGCCAAT S|170|R silent|AGC>AGT|S|170 S|172|C S|172|F URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 0.9832837071978582 P34241 0.9417110085487366 0.945252001285553 0.9294660091400146 0.03603474423289299 0.04100580140948296 0.029980534687638283 49.01087333400631 45.0 0.0 no 7561 chrXI_416402 22076 essential YKL014C 492 - TTGCTTGGTACCAACAGTCT S|170|T S|170|N URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 0.7144643319128048 P34241 0.9512869715690612 0.9536849856376648 0.6638892292976379 0.2592764794826508 50.99604413685091 45.0 0.0 no 7562 chrXI_416412r 22077 essential YKL014C 479 + ACCTATTTTACCAAGACTGT P|161|R P|161|L P|161|A P|161|S URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 -0.21784658243019567 P34241 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.09079625457525252 0.060930021107196815 0.16888056695461273 0.3497843742370605 45.13417195241635 35.0 0.0 no 7563 chrXI_416463r 22079 essential YKL014C 428 + CAACAATGGGCAACATATAG N|144|K silent|AAC>AAT|N|144 URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 1.2283887398575548 P34241 0.9439849853515624 0.09737854450941086 38.71606185060772 40.0 0.0 no 7564 chrXI_416552r 22081 essential YKL014C 339 + TACACAAAAGTTCTCTATAG Y|114|* silent|TAC>TAT|Y|114 T|115|R T|115|I URB1 Unhealthy Ribosome Biogenesis 1764.0 0 0 0 0 0.7257159840340265 P34241 0.9476869702339172 0.9472420215606691 0.12020590901374816 0.6737801432609558 35.08110043491752 30.0 0.0 no 7565 chrXI_416836 22086 essential YKL014C 58 - GTCTTCGAACTCTTTCCCTT D|26|H D|26|N E|25|Q E|25|K URB1 Unhealthy Ribosome Biogenesis 1764.0 0 1 0 0 -0.4780824669049738 P34241 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.08521509915590286 0.9776276350021362 0.04331484436988831 0.03569361940026283 53.19007818570174 45.0 0.0 no 7566 chrXI_417738r 22088 essential YKL013C 263 + TCACAAGTTTACTAGATTTT H|89|Q silent|CAC>CAT|H|89 H|89|D H|89|Y 0 1 0 0 0.3664277448740873 P33204 0.30061501264572144 0.675579845905304 0.05170552060008049 37.812661427286116 25.0 0.0 no 7567 chrXI_417806 22089 essential YKL013C 198 - ATACGCACCGAGTTTACACT R|72|P R|72|H silent|GTG>GTC|V|71 silent|GTG>GTA|V|71 0 0 0 0 -0.8434736680013072 P33204 0.043203704059123986 0.002623738721013069 48.38824699967887 45.0 0.0 no 7568 chrXI_417851 22090 essential YKL013C 153 - TCATTACGAGATATATGCAT E|58|Q E|58|K R|56|P R|56|H 0 0 0 0 -2.0516215671907965 P33204 0.12569661438465118 0.1699569970369339 0.04651966318488121 0.005475725047290325 0.040800001472234726 0.1762000024318695 6.3796000480651855 3.4518001079559326 39.33516798334381 30.0 0.0 yes 7569 chrXI_417882 22094 essential YKL013C 122 - ACAATTCGGCGCTAGTGTTA L|47|F silent|TTG>TTA|L|47 E|46|Q E|46|K 0 0 0 0 -0.2632246566903744 P33204 0.10194797813892363 0.19226908683776853 0.1495574712753296 -0.030719999223947525 2.0610001087188716 0.4754999876022339 0.13750000298023224 48.84519197466261 45.0 0.0 no 7570 chrXI_417957 22095 essential YKL013C 47 - TCAAAGTCAACGCAGCTTCC L|22|F silent|TTG>TTA|L|22 0 0 0 0 1.32667216509128 P33204 0.00845253001898527 2.7152199745178223 2.7228000164031982 48.938853705462925 50.0 0.0 no 7571 chrXI_417983 22097 essential YKL013C 21 - TAACGAACAGCCGTTAGATA R|13|P R|13|H 0 0 0 0 -0.6317427942962286 P33204 0.0027756767813116308 0.0031120423227548604 42.25254352116133 40.0 0.0 no 7572 chrXI_417993r 22098 essential YKL013C 8 + ATCATTACGTCCGTATCTAA S|4|* S|4|L 0 0 0 0 -1.0271589874794431 P33204 0.00831434316933155 -1.0978000164031982 44.18965190880681 35.0 0.0 no 7573 chrXI_418326 22099 essential YKL012W 16 + AAGCTAAAGATGCAAGTGGA A|7|G A|7|V PRP40 Pre-mRNA Processing 583.0 0 0 0 0 0.3952950986863384 P33203 0.9484469890594482 0.9504740238189696 0.0 0.0 0.6439999938011169 -0.4239799976348877 40.7090071186712 40.0 1.0 no 7574 chrXI_418378 22100 essential YKL012W 68 + ATCTACGTGGGAGAAGCCCA S|24|C S|24|F T|25|R T|25|M PRP40 Pre-mRNA Processing 583.0 0 0 0 0 0.12480855056257825 P33203 0.945252001285553 0.9294660091400146 0.9476869702339172 0.9502379894256592 0.006990034598857164 0.0036342886742204423 0.7352530956268309 0.1021743044257164 -0.3910199999809265 -0.3702600002288817 -1.2748199701309204 -1.684839963912964 53.75930026691162 55.00000000000001 1.0 no 7575 chrXI_418418 22101 essential YKL012W 108 + GAGCTACTTCTTCGAGAAAA L|38|V silent|CTA>TTA|L|38 L|39|V L|39|F PRP40 Pre-mRNA Processing 583.0 0 0 0 0 0.3170744382499916 P33203 0.9512209892272948 0.9512209892272948 0.9587849974632264 0.5420052409172058 0.5584384799003601 0.4809928238391876 2.0272998809814453 1.6541600227355957 0.7234200239181519 41.26266138171752 40.0 1.0 no 7576 chrXI_418452r 22103 essential YKL012W 145 - TACTTTGCCGTCTGCCGTCT V|55|L V|55|I PRP40 Pre-mRNA Processing 583.0 0 0 0 0 0.16042530091133572 P33203 0.9539830088615416 0.9574310183525084 0.2738196551799774 0.702688455581665 -0.08619999885559082 -0.33855998516082764 59.34069646575496 55.00000000000001 1.0 no 7577 chrXI_418541r 22105 essential YKL012W 234 - TCATGTTTTTGTTCTGCGAT D|85|H D|85|N PRP40 Pre-mRNA Processing 583.0 0 0 0 0 -0.09637929765038976 P33203 0.9486550092697144 0.956179976463318 0.13787610828876495 0.41835492849349976 46.83872493002253 35.0 1.0 no 7578 chrXI_418542r 22106 essential YKL012W 235 - ATCATGTTTTTGTTCTGCGA D|85|H D|85|N PRP40 Pre-mRNA Processing 583.0 0 0 0 0 0.6359777497017605 P33203 0.9486550092697144 0.956179976463318 0.13787610828876495 0.41835492849349976 46.83872493002253 35.0 1.0 no 7579 chrXI_418628r 22110 essential YKL012W 321 - TCCTCGTTTATAGTTCGTCC E|113|D silent|GAG>GAA|E|113 E|114|Q E|114|K PRP40 Pre-mRNA Processing 583.0 0 0 0 0 -2.425192083861936 P33203 0.94931298494339 0.956179976463318 0.9475290179252625 0.6139487028121948 0.4759262800216675 0.7035611867904663 52.75161356298872 45.0 1.0 yes 7580 chrXI_418731r 22113 essential YKL012W 424 - TACTTGATTTTCCTTCAGCA V|148|L V|148|I PRP40 Pre-mRNA Processing 583.0 0 0 0 0 0.7597555185100761 P33203 0.9539830088615416 0.9574310183525084 0.0469551607966423 0.3238405883312225 3.5316278934478764 3.3514919281005864 5.210671901702881 2.221276044845581 47.535879706096296 35.0 1.0 no 7581 chrXI_418797r 22116 essential YKL012W 490 - CATCCAATACCTTGGATCTC W|169|C W|169|* W|169|S W|169|* PRP40 Pre-mRNA Processing 583.0 0 0 0 0 -0.8211361835332929 P33203 0.8858469724655151 0.8858469724655151 0.0 0.0 1.6038479804992676 1.3919219970703125 1.0149860382080078 0.6002460122108461 48.29642507965464 45.0 1.0 no 7582 chrXI_418831r 22117 essential YKL012W 524 - ACATTTCTTTCTTCCATAAG M|181|I M|181|I E|180|Q E|180|K PRP40 Pre-mRNA Processing 583.0 0 0 0 0 0.6551601537226568 P33203 0.9553959965705872 0.9553959965705872 0.956179976463318 0.9475290179252625 0.6217302083969116 0.6217302083969116 1.0 0.31847286224365234 0.6492120027542114 0.6492120027542114 0.026906000450253487 -0.1454319953918457 41.945941901242975 30.0 1.0 no 7583 chrXI_418833r 22118 essential YKL012W 526 - AAACATTTCTTTCTTCCATA M|181|I M|181|I PRP40 Pre-mRNA Processing 583.0 0 0 0 0 0.4121010658507451 P33203 0.9553959965705872 0.9553959965705872 0.6217302083969116 0.6217302083969116 0.6492120027542114 0.6492120027542114 40.457765206777026 25.0 1.0 no 7584 chrXI_418986r 22122 essential YKL012W 679 - GTCGGCAATTAGTCTCTTTG D|233|H D|233|N A|232|P A|232|T PRP40 Pre-mRNA Processing 583.0 0 0 0 0 0.8941850142329669 P33203 0.9486550092697144 0.956179976463318 0.9573720097541808 0.9523990154266356 0.02903936617076397 1.0 0.0750182718038559 0.09907937794923782 48.40093923517014 45.0 1.0 no 7585 chrXI_419011 22123 essential YKL012W 701 + ACCAATATACAAACACTCCG P|235|R P|235|L P|235|A P|235|S PRP40 Pre-mRNA Processing 583.0 0 0 0 0 -0.01664220171364139 P33203 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 41.456151572978285 40.0 1.0 no 7586 chrXI_419080r 22124 essential YKL012W 773 - ATTCTTTCTGAGTGTCGATG E|264|Q E|264|K PRP40 Pre-mRNA Processing 583.0 0 0 0 0 0.3801291103436107 P33203 0.956179976463318 0.9475290179252625 0.5350141525268555 0.8408141136169434 45.380918510366705 40.0 1.0 no 7587 chrXI_419079r 22125 essential YKL012W 772 - TTCTTTCTGAGTGTCGATGA E|264|Q E|264|K Q|262|H silent|CAG>CAA|Q|262 PRP40 Pre-mRNA Processing 583.0 0 0 0 0 0.016025352913704573 P33203 0.956179976463318 0.9475290179252625 0.9570760130882264 0.5350141525268555 0.8408141136169434 0.5011023283004761 46.67897698082721 40.0 1.0 no 7588 chrXI_418832r 22126 essential YKL012W 525 - AACATTTCTTTCTTCCATAA M|181|I M|181|I PRP40 Pre-mRNA Processing 583.0 0 0 0 0 -0.002809385882906689 P33203 0.9553959965705872 0.9553959965705872 0.6217302083969116 0.6217302083969116 0.6492120027542114 0.6492120027542114 40.45776520677697 25.0 1.0 no 7589 chrXI_419135 22127 essential YKL012W 825 + GAACTAAGAGAGTATTTAAA L|277|V silent|CTA>TTA|L|277 PRP40 Pre-mRNA Processing 583.0 0 0 0 0 0.52415125180188 P33203 0.9512209892272948 0.16751451790332794 31.13762059054659 25.0 1.0 no 7590 chrXI_419175 22128 essential YKL012W 865 + CCTCTGAAACTTTCATAACC S|290|C S|290|F silent|TCC>TCG|S|289 silent|TCC>TCT|S|289 PRP40 Pre-mRNA Processing 583.0 0 0 0 0 0.486632875526812 P33203 0.945252001285553 0.9294660091400146 0.05267181247472763 0.049717601388692856 43.23770458548597 40.0 1.0 no 7591 chrXI_419272r 22129 essential YKL012W 965 - ACTCGTTTAAAACATCTTCG E|328|Q E|328|K E|328|D silent|GAG>GAA|E|328 PRP40 Pre-mRNA Processing 583.0 0 0 0 0 -0.3375184478442351 P33203 0.956179976463318 0.9475290179252625 0.94931298494339 0.38356876373291016 0.3664771020412445 0.3351815044879913 39.0967060038584 35.0 1.0 no 7592 chrXI_419271r 22130 essential YKL012W 964 - CTCGTTTAAAACATCTTCGT E|328|Q E|328|K PRP40 Pre-mRNA Processing 583.0 0 0 0 0 0.8655659780703749 P33203 0.956179976463318 0.9475290179252625 0.38356876373291016 0.3664771020412445 40.95816656274491 35.0 1.0 no 7593 chrXI_419477 22132 essential YKL012W 1167 + CCGCGCTTTTTACATATGCT R|391|G R|391|C P|390|R P|390|L PRP40 Pre-mRNA Processing 583.0 0 0 0 0 -1.0800604957457218 P33203 0.8994590044021606 0.8926740288734436 0.9432820081710817 0.9430609941482544 0.3580493032932281 0.05218704044818878 0.1372435986995697 0.07729920744895935 51.34564836100867 45.0 1.0 no 7594 chrXI_435663r 22137 essential YKL004W 86 - GCACCTTCAACAACGTTTGA V|35|L V|35|M silent|GTG>GTC|V|35 silent|GTG>GTA|V|35 0 0 0 0 0.4237138536847653 P36107 1.0 0.09787896275520323 47.31057103154399 45.0 1.0 no 7595 chrXI_435755 22140 essential YKL004W 175 + TCATTACTAATCCCGCACCT F|59|L silent|TTC>TTT|F|59 T|61|S T|61|I 0 0 0 0 0.9467318729632858 P36107 1.0 0.023634141311049458 0.7757569551467896 51.838095463193376 45.0 1.0 no 7596 chrXI_435851 22141 essential YKL004W 271 + ATGCCTTGCCCATCCTAACA A|92|G A|92|V silent|GCC>GCG|A|92 silent|GCC>GCT|A|92 0 0 0 0 0.3132815403137285 P36107 0.6393492817878723 0.1182861551642418 56.92816587619643 50.0 1.0 no 7597 chrXI_435919r 22145 essential YKL004W 342 - AACACTTTGACAGTAATAGG silent|GTG>GTC|V|120 silent|GTG>GTA|V|120 V|120|L V|120|M 0 0 0 0 -0.3687548849244618 P36107 0.2245510220527649 0.020621808245778084 37.739048653837074 35.0 1.0 no 7598 chrXI_435927 22147 essential YKL004W 347 + TACTGTCAAAGTGTTACCAG T|117|S T|117|I silent|GTC>GTG|V|118 silent|GTC>GTT|V|118 0 0 0 0 -1.110042437200042 P36107 0.8924373388290405 0.3758496046066284 43.163361234912884 40.0 1.0 no 7599 chrXI_436007 22149 essential YKL004W 427 + CCTTTTTGGACATTTTAGCA silent|TCC>TCG|S|143 silent|TCC>TCT|S|143 0 0 0 0 0.4897208121330274 P36107 46.561440063160155 35.0 1.0 no 7600 chrXI_436033 22150 essential YKL004W 453 + CCGTACGGACTATTTCATTT P|152|R P|152|L Y|153|* silent|TAC>TAT|Y|153 0 0 0 0 -1.5306247243102262 P36107 0.0 0.0 46.4964048951843 40.0 1.0 no 7601 chrXI_436033r 22151 essential YKL004W 456 - CCAAAATGAAATAGTCCGTA G|159|R G|159|R 0 0 0 0 -2.3220664952016703 P36107 0.023322617635130882 0.023322617635130882 38.865333436323056 35.0 1.0 yes 7602 chrXI_436007r 22152 essential YKL004W 430 - CCATGCTAAAATGTCCAAAA W|150|S W|150|* A|149|P A|149|T 0 0 0 0 -0.6054945176276275 P36107 0.0 0.018639283254742626 0.01863080263137817 39.60193445741038 35.0 1.0 no 7603 chrXI_436186r 22156 essential YKL004W 609 - CCATAGAGAATTTTATACCA G|210|R G|210|R 0 0 0 0 -0.3494255203790897 P36107 0.009330106899142264 0.009330106899142264 40.310957592068746 30.0 1.0 no 7604 chrXI_436216 22157 essential YKL004W 636 + TCAGCCAACTATGATATGCA S|213|* S|213|L A|214|G A|214|V 0 0 0 0 0.13432430607419438 P36107 0.011907999403774738 0.0 0.0 46.14740486721132 40.0 1.0 no 7605 chrXI_436243r 22158 essential YKL004W 666 - TCAATTCTAGCTAATCCACC D|229|H D|229|N R|227|T R|227|K 0 0 0 0 -4.059603089658192 P36107 0.0 0.0 0.0 0.0 46.366864809881285 40.0 1.0 yes 7606 chrXI_436303 22159 essential YKL004W 723 + TCAAATTCCTCCGTCATTTT S|242|* S|242|L 0 0 0 0 0.39762873144711175 P36107 0.03579951450228691 46.95348633069625 35.0 1.0 no 7607 chrXI_436327 22160 essential YKL004W 747 + GCTTTTCCTTCACTGCATTC A|250|G A|250|V P|252|A P|252|S 0 0 0 0 0.6023285573591753 P36107 0.0 0.0 0.0 0.0 53.73755166558527 45.0 1.0 no 7608 chrXI_436341 22161 essential YKL004W 761 + GCATTCCGGGTGTGCTACTA H|255|D H|255|Y S|256|C S|256|F 0 0 0 0 -6.31514672465797 P36107 0.0 0.0 0.0 0.0 57.180850879435866 55.00000000000001 1.0 yes 7609 chrXI_436412 22163 essential YKL004W 832 + TTGCTTATGTTTGCTGGTTA A|279|G A|279|V 0 0 0 0 0.6899673741583456 P36107 0.3905656039714813 0.5268437862396239 48.01934052427947 35.0 1.0 no 7610 chrXI_436458 22164 essential YKL004W 878 + CCATTATTTTGTAGACCTTA H|294|D H|294|Y 0 0 0 0 -0.7283953326876723 P36107 0.0 0.0 43.915429528533316 30.0 1.0 no 7611 chrXI_443258 22166 essential YKR002W 26 + TACTGGACCTGTTTCCACCG T|10|S T|10|I PAP1 Poly(A) Polymerase 568.0 0 0 0 0 -1.6145071171271956 P29468 0.9491789937019348 0.9472420215606691 0.10987649857997894 0.003042762167751789 -0.029219999909400936 -0.3679400086402893 54.823219074185715 55.00000000000001 1.0 no 7612 chrXI_443368r 22170 essential YKR002W 139 - TTTCAACACTTGTACCCTAT L|52|F silent|TTG>TTA|L|52 silent|GTG>GTC|V|51 silent|GTG>GTA|V|51 PAP1 Poly(A) Polymerase 568.0 0 0 0 0 -0.7232847548063142 P29468 0.9587849974632264 0.012840429320931436 3.5364000797271733 46.144012029661724 35.0 1.0 no 7613 chrXI_443497 22174 essential YKR002W 265 + CCTATAGACTAGGAGTCCAT silent|TCC>TCG|S|89 silent|TCC>TCT|S|89 PAP1 Poly(A) Polymerase 568.0 0 0 0 0 0.09412801334503576 P29468 49.296755862112725 45.0 1.0 no 7614 chrXI_443497r 22175 essential YKR002W 268 - CCCATGGACTCCTAGTCTAT G|96|R G|96|R G|96|A G|96|E PAP1 Poly(A) Polymerase 568.0 0 1 0 0 0.4269302640854499 P29468 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.004556188825517893 0.004556188825517893 0.03466647118330002 0.005990756675601006 -0.2928400039672852 -0.2928400039672852 0.18998000025749207 -0.15817999839782715 55.13982898756411 50.0 1.0 no 7615 chrXI_443553r 22177 essential YKR002W 324 - TCTTCCCGAGTTACATGTTT D|115|H D|115|N E|114|Q E|114|K PAP1 Poly(A) Polymerase 568.0 0 0 0 0 -0.505987878656649 P29468 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.004462882876396179 0.06540326774120331 0.04276162385940552 0.0348033681511879 -0.580020010471344 0.4083200097084045 0.303600013256073 0.3388400077819824 50.58798818969973 40.0 1.0 no 7616 chrXI_443835r 22181 essential YKR002W 606 - ATTCTGAAAACATTCGGCTT R|208|T R|208|K PAP1 Poly(A) Polymerase 568.0 0 0 0 0 0.39207530712633465 P29468 0.932735025882721 0.955805003643036 0.008681257255375384 0.4519360363483429 0.6419600248336792 -0.3625400066375733 41.49534409221053 35.0 1.0 no 7617 chrXI_443885r 22182 essential YKR002W 656 - TAGCATAAACAGCCCTTCTT A|225|P A|225|T PAP1 Poly(A) Polymerase 568.0 0 0 0 0 0.3945305252416871 P29468 0.9573720097541808 0.9523990154266356 0.04146403819322586 0.030441125854849812 6.85860013961792 2.564059972763061 6.901480197906494 1.5625200271606443 48.28933616308649 40.0 1.0 no 7618 chrXI_443895 22183 essential YKR002W 663 + GCTGTTTATGCTAATATTTT A|222|G A|222|V PAP1 Poly(A) Polymerase 568.0 0 0 0 0 0.6574877536473364 P29468 0.9484469890594482 0.9504740238189696 0.09243842959403993 0.006329310592263937 -0.3350600004196167 3.5741000175476074 -2.765199899673462 1.9682999849319456 40.675745181607745 25.0 1.0 no 7619 chrXI_443941r 22184 essential YKR002W 712 - ACAAATTCTAGCCACTAGCA C|244|S C|244|Y PAP1 Poly(A) Polymerase 568.0 0 0 0 0 -0.0825627718703534 P29468 0.9421560168266296 0.9290120005607604 0.0 0.0 0.5502200126647949 9.33627986907959 46.02469366746743 40.0 1.0 no 7620 chrXI_444048 22187 essential YKR002W 816 + ATCTTGAAACCAATTGAGGA I|273|M silent|ATC>ATT|I|273 PAP1 Poly(A) Polymerase 568.0 0 0 0 0 1.0150860332485538 P29468 0.9598389863967896 0.12419164925813675 0.2797999978065491 -0.15892000496387482 39.97862956521038 35.0 1.0 no 7621 chrXI_444071r 22188 essential YKR002W 842 - TCCATACACGAACTTGTAAC W|287|S W|287|* W|287|C W|287|* PAP1 Poly(A) Polymerase 568.0 0 0 0 0 -3.6849456668580935 P29468 0.8858469724655151 0.8858469724655151 0.0 0.0 6.361020088195801 5.29994010925293 5.892739772796631 4.380939960479736 41.577413243548854 40.0 1.0 yes 7622 chrXI_444454r 22192 essential YKR002W 1225 - ACAACAATAACTACTTTCAA C|415|S C|415|Y C|414|S C|414|Y PAP1 Poly(A) Polymerase 568.0 0 0 0 0 0.5447739235762442 P29468 0.9421560168266296 0.9290120005607604 0.9421560168266296 0.9290120005607604 0.0592699907720089 0.2719104290008545 0.397812694311142 1.0 1.063480019569397 20.21026039123535 0.7498199939727783 -0.9444199800491332 1.186619997024536 16.594419479370114 0.6924999952316284 -0.2246199995279312 33.83004249345737 25.0 1.0 no 7623 chrXI_444481r 22193 essential YKR002W 1252 - AATCATTTCATAGTCATCCT M|423|I M|423|I PAP1 Poly(A) Polymerase 568.0 0 0 0 0 -0.4616881641578449 P29468 0.9553959965705872 0.9553959965705872 0.1846689879894257 0.1846689879894257 1.9403400421142576 1.9403400421142576 1.2188800573349 1.2188800573349 43.739686081880556 30.0 1.0 no 7624 chrXI_447093r 22195 essential YKR004C 817 + TTACTCAGGAATTAGTAAAA T|274|S T|274|I Q|275|E Q|275|* ECM9 ExtraCellular Mutant 377.0 0 0 0 0 -0.4811966386703481 Q02202 0.9245100021362304 0.9225580096244812 0.922443985939026 0.33129191398620605 0.5280250906944275 1.0 33.25924939278519 25.0 0.0 no 7625 chrXI_447148 22198 essential YKR004C 765 - TCCACTTTATTTATCTTGAA silent|GTG>GTC|V|261 silent|GTG>GTA|V|261 D|262|H D|262|N ECM9 ExtraCellular Mutant 377.0 0 0 0 0 -0.5014538467513233 Q02202 0.9728149771690368 0.9840490221977234 0.3280789852142334 0.6410081386566162 40.285844594171635 25.0 0.0 no 7626 chrXI_447437r 22199 essential YKR004C 473 + ATCTCTTGATGCTAATACAC S|159|C S|159|F L|160|V L|160|F ECM9 ExtraCellular Mutant 377.0 0 0 0 0 0.5684770919741042 Q02202 0.9720100164413452 0.9521960020065308 0.9779649972915648 0.9867290258407592 0.07016032189130783 0.10149546712636948 0.15733392536640167 0.1290571093559265 41.264543408047984 35.0 0.0 no 7627 chrXI_447486r 22200 essential YKR004C 424 + TCAACAAGTCGTCATCTCTT I|142|M silent|ATC>ATT|I|142 N|143|K silent|AAC>AAT|N|143 ECM9 ExtraCellular Mutant 377.0 0 0 0 0 -0.8766226463827371 Q02202 0.9863510131835938 0.9035819768905641 0.042628973722457886 0.0 45.75821009157954 40.0 0.0 no 7628 chrXI_447550 22201 essential YKR004C 363 - ACTTCTTTGACCAATAAATC V|128|L V|128|I E|127|Q E|127|K ECM9 ExtraCellular Mutant 377.0 0 0 0 0 -0.7623119496801496 Q02202 0.9786369800567628 0.9863060116767884 0.9209830164909364 0.9089339971542358 1.0 0.4797800779342651 0.0 0.0 38.058376001200884 30.0 0.0 no 7629 chrXI_447575 22203 essential YKR004C 338 - TTACTAAAACACTGTTGTCC V|119|L V|119|I ECM9 ExtraCellular Mutant 377.0 0 0 0 0 -0.005511684684194551 Q02202 0.9769399762153624 0.9846090078353882 0.21819479763507846 0.13314351439476013 40.35140982917636 35.0 0.0 no 7630 chrXI_447635r 22204 essential YKR004C 275 + TACAACACCTGAAAACAAAA T|93|R T|93|I T|94|R T|94|I ECM9 ExtraCellular Mutant 377.0 0 0 0 0 0.8750429424075771 Q02202 0.9621130228042604 0.9739249944686891 0.960204005241394 0.9722279906272888 0.046955477446317666 0.11527685821056365 0.0 0.0 33.026538601464665 30.0 0.0 no 7631 chrXI_447903 22205 essential YKR004C 114 - GCTTTTTCGTCTACGTAGTA A|45|P A|45|T ECM9 ExtraCellular Mutant 377.0 0 0 0 0 0.09189146414008048 Q02202 0.920873999595642 0.912581980228424 0.288391649723053 0.4578603506088257 48.62392247323396 40.0 0.0 no 7632 chrXI_447997 22206 essential YKR004C 20 - TTTCAAAAAATTCTCTGCAA E|13|Q E|13|K ECM9 ExtraCellular Mutant 377.0 0 0 0 0 0.0838589158788165 Q02202 0.9202449917793274 0.9081959724426271 0.5823509693145752 0.07714557647705078 34.66413045489014 25.0 0.0 no 7633 chrXI_447998 22207 essential YKR004C 19 - TTCAAAAAATTCTCTGCAAA E|13|Q E|13|K ECM9 ExtraCellular Mutant 377.0 0 0 0 0 0.21161767076953908 Q02202 0.9202449917793274 0.9081959724426271 0.5823509693145752 0.07714557647705078 33.32735522968903 25.0 0.0 no 7634 chrXI_452235r 22209 essential YKR008W 37 - AGGCCTTTCATCACTGCCAC R|18|S silent|AGG>AGA|R|18 R|18|T R|18|K RSC4 Remodel the Structure of Chromatin 625.0 0 0 0 0 0.3761517810590568 Q02206 0.574735164642334 0.4690434634685517 1.0 0.8374199867248535 0.8247799873352051 0.4840599894523621 0.12705999612808228 0.2947199940681457 0.2606000006198883 57.904918984083736 55.00000000000001 1.0 no 7635 chrXI_452330r 22211 essential YKR008W 132 - TCTAGAAAAAGTTCAGATTT D|51|H D|51|N RSC4 Remodel the Structure of Chromatin 625.0 0 0 0 0 -0.4997530835127119 Q02206 0.01642121933400631 0.21766388416290286 -0.7339400053024292 -0.3850800096988678 33.7337399413679 25.0 1.0 no 7636 chrXI_452319r 22212 essential YKR008W 121 - TTCAGATTTAGGGTTTAATG E|47|Q E|47|K RSC4 Remodel the Structure of Chromatin 625.0 0 0 0 0 -3.850118945059638 Q02206 0.0 0.0 0.23240000009536746 1.0841599702835083 38.62013902794683 30.0 1.0 yes 7637 chrXI_452377 22213 essential YKR008W 176 + TCGATTTATTAGTTTCACTT R|60|G R|60|* RSC4 Remodel the Structure of Chromatin 625.0 0 0 0 0 0.7011829055523039 Q02206 0.3338750004768372 1.024799942970276 40.075390199811004 25.0 1.0 no 7638 chrXI_452798r 22216 essential YKR008W 600 - ACTTTGTCGTCTAAGTTTTT V|207|L V|207|I RSC4 Remodel the Structure of Chromatin 625.0 0 0 0 0 0.13397232749560015 Q02206 1.0 0.23884452879428866 -0.2592599987983704 -0.3434799909591675 -0.8216000199317932 -0.7666199803352356 43.56244674177441 30.0 1.0 no 7639 chrXI_452867r 22217 essential YKR008W 669 - TGCACTATTTCATAATATTC silent|GTG>GTC|V|229 silent|GTG>GTA|V|229 V|229|L V|229|M RSC4 Remodel the Structure of Chromatin 625.0 0 0 0 0 0.8209841272561562 Q02206 0.042180806398391724 0.00800933316349983 0.4928399920463562 1.420560002326965 0.03537999838590622 -0.030640000477433205 37.19882448061958 25.0 1.0 no 7640 chrXI_452631r 22219 essential YKR008W 433 - AATCAACATTACTACTTGCA L|150|F silent|TTG>TTA|L|150 M|149|I M|149|I RSC4 Remodel the Structure of Chromatin 625.0 0 0 0 0 -0.28055311387251874 Q02206 0.5971407294273376 0.4811418354511261 0.4811418354511261 -0.928879976272583 2.7776999473571777 2.7776999473571777 39.31154502603107 30.0 1.0 no 7641 chrXI_453083r 22221 essential YKR008W 885 - TCATTTAAATCCTGTAACTC E|302|Q E|302|K RSC4 Remodel the Structure of Chromatin 625.0 0 0 0 0 0.4264122234593603 Q02206 0.0 0.0 -0.6675999760627747 -0.41477999091148376 38.862682181742464 30.0 1.0 no 7642 chrXI_453143 22222 essential YKR008W 942 + TTCGAAAACTACTTAGCTAT F|315|L silent|TTC>TTT|F|315 RSC4 Remodel the Structure of Chromatin 625.0 0 0 0 0 0.5381623466895212 Q02206 0.04497919976711273 1.7267999649047852 37.46597511256636 30.0 1.0 no 7643 chrXI_453316r 22224 essential YKR008W 1118 - TCAGTAAATAATCTTCAGTT silent|CTG>CTC|L|379 silent|CTG>CTA|L|379 RSC4 Remodel the Structure of Chromatin 625.0 0 0 0 0 -0.3913526465165396 Q02206 36.38053871926678 25.0 1.0 no 7644 chrXI_482413r 22226 essential YKR022C 704 + CTACAGAACTAATGAAGAAT Y|236|* silent|TAC>TAT|Y|236 0 0 0 0 0.04653496773500987 P36118 32.66389619247923 30.0 0.0 no 7645 chrXI_482414 22227 essential YKR022C 706 - CCATTCTTCATTAGTTCTGT W|242|S W|242|* E|241|Q E|241|K 0 0 0 0 -0.593949506260079 P36118 0.013048384338617323 0.4419785439968109 0.6658284664154053 48.16810506737403 35.0 0.0 no 7646 chrXI_482488 22228 essential YKR022C 632 - TAGCAATTTGATTATCCGTG A|217|P A|217|T 0 0 0 0 0.5040698218014871 P36118 0.3228381276130676 0.6671288013458252 42.25666571897386 35.0 0.0 no 7647 chrXI_482503r 22229 essential YKR022C 614 + AGACGAAATGCTAGCCCTCA D|206|E silent|GAC>GAT|D|206 0 0 0 0 -0.4114056022740329 P36118 0.3859462738037109 50.32296554735837 50.0 0.0 no 7648 chrXI_482532r 22230 essential YKR022C 585 + TTCAGTGACGATGAAATGCA F|196|L silent|TTC>TTT|F|196 0 1 0 0 -0.1211127500688951 P36118 0.7067679762840271 41.737728536009634 40.0 0.0 no 7649 chrXI_482690r 22232 essential YKR022C 427 + CACAGAAGTCATTATCTAGA Q|144|E Q|144|* 0 1 0 0 0.3731082996153116 P36118 0.6977118849754333 39.96175999380785 35.0 0.0 no 7650 chrXI_482716 22233 essential YKR022C 404 - TCAGTTTTGCAATTTCTCCT silent|CTG>CTC|L|141 silent|CTG>CTA|L|141 0 0 0 0 0.2575961898785492 P36118 48.49765459265996 35.0 0.0 no 7651 chrXI_483016 22235 essential YKR022C 104 - CTTCAGAATCGTTCGACACT E|41|Q E|41|K 0 1 0 0 0.4944440117916151 P36118 0.08318186551332474 0.07047544419765472 45.75680868208957 45.0 0.0 no 7652 chrXI_483017 22236 essential YKR022C 103 - TTCAGAATCGTTCGACACTA E|41|Q E|41|K 0 1 0 0 -0.3296239050059377 P36118 0.08318186551332474 0.07047544419765472 43.459808417853424 40.0 0.0 no 7653 chrXI_483072 22238 essential YKR022C 48 - CCATCAATTCCAACCTCCTC G|23|R G|23|S D|22|H D|22|N 0 0 0 0 0.09924238238646983 P36118 0.3269729018211365 0.6192478537559509 0.13846591114997864 1.0 53.25281472411092 50.0 0.0 no 7654 chrXI_485713 22243 high_effect YKR024C 1640 - TACGACCAACTCTATGTAAA R|553|P R|553|H G|552|A G|552|D DBP7 Dead Box Protein 742.0 0 0 0 0 -4.524157146205632 P36120 0.0 0.0 0.0 0.0 39.560311548001955 35.0 0.0 yes 7655 chrXI_485762 22245 high_effect YKR024C 1591 - CTCAATAACAGATCCAACGT E|537|Q E|537|K DBP7 Dead Box Protein 742.0 0 0 0 0 -0.7940235134825706 P36120 0.11052487790584564 0.015537479892373085 41.829296321656216 40.0 0.0 no 7656 chrXI_485767 22247 high_effect YKR024C 1586 - TAACAGATCCAACGTGGGGA V|535|L V|535|I DBP7 Dead Box Protein 742.0 0 0 0 0 0.43891430348289023 P36120 0.0 0.0 47.19833627316802 50.0 0.0 no 7657 chrXI_485973r 22249 high_effect YKR024C 1377 + TCTGTAAGACTATTGACAAA S|460|C S|460|F DBP7 Dead Box Protein 742.0 0 0 0 0 1.0212344634530175 P36120 0.19085533916950226 0.7115146517753601 35.903494403634 30.0 0.0 no 7658 chrXI_485995 22250 high_effect YKR024C 1358 - AATCACCCGTTAGATTTTTA D|459|H D|459|N G|458|A G|458|D DBP7 Dead Box Protein 742.0 0 0 0 0 0.8816327805667633 P36120 0.17861321568489075 0.3513892889022827 0.7378235459327698 0.6050636768341064 43.40075948157993 30.0 0.0 no 7659 chrXI_486080 22253 high_effect YKR024C 1273 - TACGATTGTACGCAGCGTTT V|431|L V|431|I DBP7 Dead Box Protein 742.0 0 0 0 0 0.05134175554880248 P36120 0.027057712897658348 0.12601277232170105 48.20932339052149 45.0 0.0 no 7660 chrXI_486030r 22255 high_effect YKR024C 1320 + TTTCATTATGACGCATTTTC H|442|D H|442|Y DBP7 Dead Box Protein 742.0 0 0 0 0 0.2844860067386181 P36120 0.0 0.0 41.33612860949631 30.0 0.0 no 7661 chrXI_486111r 22256 high_effect YKR024C 1239 + ACCAAAGATTTCATCGCTTC silent|ACC>ACG|T|414 silent|ACC>ACT|T|414 T|414|S T|414|I DBP7 Dead Box Protein 742.0 0 0 0 0 0.6145400410998656 P36120 0.8352721333503723 0.3043181598186493 44.78814601598845 40.0 0.0 no 7662 chrXI_486224 22257 high_effect YKR024C 1129 - TACTATATCAGAATCTTTCT V|383|L V|383|I DBP7 Dead Box Protein 742.0 0 0 0 0 -0.10106532712460756 P36120 0.32093775272369385 0.20036053657531736 37.6884066765831 25.0 0.0 no 7663 chrXI_486327 22258 high_effect YKR024C 1026 - AACATGTGCACTAACTTATG M|348|I M|348|I DBP7 Dead Box Protein 742.0 0 0 0 0 0.8379346524670228 P36120 0.2343540042638779 0.2343540042638779 39.275963658719775 35.0 0.0 no 7664 chrXI_486335 22259 high_effect YKR024C 1018 - CACTAACTTATGCGGTAGCT V|346|L V|346|M K|344|N silent|AAG>AAA|K|344 DBP7 Dead Box Protein 742.0 0 0 0 0 0.3781401202735864 P36120 0.1938163936138153 0.011863878928124905 0.02104044146835804 47.426819404035825 45.0 0.0 no 7665 chrXI_486454r 22261 high_effect YKR024C 896 + ATCTCTAAGGTATATCGTAT S|300|C S|300|F L|301|V silent|CTA>TTA|L|301 DBP7 Dead Box Protein 742.0 0 0 0 0 0.12255353210967368 P36120 0.03761427477002144 0.03592204675078392 1.0 40.640808994105896 30.0 0.0 no 7666 chrXI_486490r 22263 high_effect YKR024C 860 + ACAAAATACAAAAGTTATCA Q|288|E Q|288|* DBP7 Dead Box Protein 742.0 0 0 0 0 0.12581649391957686 P36120 1.0 29.446747356599868 20.0 0.0 no 7667 chrXI_486779 22265 high_effect YKR024C 574 - AGTCTTACCTGAGCCTGTTT K|197|N silent|AAG>AAA|K|197 DBP7 Dead Box Protein 742.0 0 0 0 0 -1.2128875220438942 P36120 0.0 54.712187265451185 45.0 0.0 no 7668 chrXI_486786r 22266 high_effect YKR024C 564 + ATTCACGCCCAAACAGGCTC H|190|D H|190|Y H|190|Q silent|CAC>CAT|H|190 DBP7 Dead Box Protein 742.0 0 0 0 0 -0.06267823022178322 P36120 0.017909850925207138 0.014440941624343397 1.0 53.10521965886488 55.00000000000001 0.0 no 7669 chrXI_486824r 22267 high_effect YKR024C 526 + CTCAAATAATAGGTAACGCG Q|177|E Q|177|* DBP7 Dead Box Protein 742.0 0 0 0 0 -0.2301819328872569 P36120 0.8541858792304993 38.01631680572831 40.0 0.0 no 7670 chrXI_486825 22268 high_effect YKR024C 528 - CCCGCGTTACCTATTATTTG silent|GCG>GCC|A|182 silent|GCG>GCA|A|182 G|183|R G|183|R DBP7 Dead Box Protein 742.0 0 0 0 0 -0.025255494102824738 P36120 0.8045747876167297 0.8045747876167297 50.47711555706803 45.0 0.0 no 7671 chrXI_486826r 22270 high_effect YKR024C 524 + ACCTCAAATAATAGGTAACG P|176|R P|176|L P|176|A P|176|S DBP7 Dead Box Protein 742.0 0 0 0 0 0.17884402300166635 P36120 0.009115700609982014 0.010302940383553505 0.04493361338973045 0.04557554423809052 37.36261645337612 35.0 0.0 no 7672 chrXI_486852 22271 high_effect YKR024C 501 - GCCTGCTTCTGGATGCTCGT Q|173|H silent|CAG>CAA|Q|173 A|174|P A|174|T DBP7 Dead Box Protein 742.0 0 1 0 0 -0.02182305131462248 P36120 0.14231693744659424 0.13435734808444974 0.5924527645111084 61.325422765426985 60.0 0.0 no 7673 chrXI_486936 22273 high_effect YKR024C 417 - GCAAACTGATCACCTTTCAA A|146|P A|146|T Q|144|H silent|CAG>CAA|Q|144 DBP7 Dead Box Protein 742.0 0 0 0 0 0.7345159085948809 P36120 0.2876337468624115 0.5768100023269653 0.027734994888305664 44.32820639260165 40.0 0.0 no 7674 chrXI_486935 22274 high_effect YKR024C 418 - CGCAAACTGATCACCTTTCA A|146|P A|146|T Q|144|H silent|CAG>CAA|Q|144 DBP7 Dead Box Protein 742.0 0 0 0 0 0.2451459296268477 P36120 0.2876337468624115 0.5768100023269653 0.027734994888305664 46.88370961017836 45.0 0.0 no 7675 chrXI_486948 22275 high_effect YKR024C 405 - CCTTTCAAGGGCGCGTTAGA G|142|R G|142|S L|140|F silent|TTG>TTA|L|140 DBP7 Dead Box Protein 742.0 0 0 0 0 0.370750500332077 P36120 0.30880242586135864 0.6351506114006042 0.06389916688203813 53.8640225190386 55.00000000000001 0.0 no 7676 chrXI_486948r 22276 high_effect YKR024C 402 + CCGTCTAACGCGCCCTTGAA P|135|R P|135|L S|136|C S|136|F DBP7 Dead Box Protein 742.0 0 0 0 0 -0.10507985180786084 P36120 0.00672547146677971 0.008688121102750301 0.003428465686738491 0.0022032218985259533 55.406810115068886 60.0 0.0 no 7677 chrXI_487144r 22280 high_effect YKR024C 206 + TTCTATTAAAAAATTGCATA S|70|C S|70|F DBP7 Dead Box Protein 742.0 0 0 0 0 0.4146910851476707 P36120 0.05192817375063896 0.05025354772806168 29.92659453215361 15.0 0.0 no 7678 chrXI_487274 22282 high_effect YKR024C 79 - CCATCTACCGCCTGTCACCT W|33|S W|33|* R|32|T R|32|K DBP7 Dead Box Protein 742.0 0 0 0 0 -1.7278345223490144 P36120 0.0 0.16470442712306976 0.6756024360656738 61.48687650413609 60.0 0.0 no 7679 chrXI_487317r 22285 high_effect YKR024C 33 + ACTACCAATGAGGACACTGC T|12|S T|12|I T|13|S T|13|I DBP7 Dead Box Protein 742.0 0 0 0 0 1.2359031494232549 P36120 0.8334004282951355 0.09886592626571657 0.4885453879833221 0.598884642124176 47.472386254198845 50.0 0.0 no 7680 chrXI_487829r 22287 essential YKR025W 62 - ATTCATCCTCAACATCAGCA E|27|Q E|27|K D|26|H D|26|N RPC37 RNA Polymerase C 282.0 0 0 0 0 0.15108735060848522 P36121 48.33262742546538 40.0 1.0 no 7681 chrXI_487853 22288 essential YKR025W 83 + TAACGACATTGATATGATAG N|29|K silent|AAC>AAT|N|29 D|30|E silent|GAC>GAT|D|30 RPC37 RNA Polymerase C 282.0 0 0 0 0 0.4395382777278529 P36121 34.12945217580068 30.0 1.0 no 7682 chrXI_487924r 22289 essential YKR025W 157 - ATCTTCAGCTTTTACTTCTT D|59|H D|59|N E|58|Q E|58|K RPC37 RNA Polymerase C 282.0 0 1 0 0 0.27616699244891113 P36121 0.13998615741729736 0.7812324166297913 0.2739681899547577 0.6007477045059204 46.07419781584417 30.0 1.0 no 7683 chrXI_488032 22292 essential YKR025W 262 + TTCAGTATGCTAATAGACCA Q|89|E Q|89|* RPC37 RNA Polymerase C 282.0 0 0 0 0 -1.2603681606255042 P36121 0.0 43.50707918073636 35.0 1.0 no 7684 chrXI_488082r 22293 essential YKR025W 315 - TATCTTGCTGCAGAGATAAA R|111|T R|111|K RPC37 RNA Polymerase C 282.0 0 0 0 0 0.2412211923396938 P36121 0.0 0.0 41.11044967998731 35.0 1.0 no 7685 chrXI_488379r 22299 essential YKR025W 612 - ACTTGAGCGCGTTGTGATGA V|211|L V|211|M RPC37 RNA Polymerase C 282.0 0 0 0 0 0.3985463445609248 P36121 0.0 0.0 50.36518539227428 50.0 1.0 no 7686 chrXI_511112 22302 essential YKR037C 666 - TCCTGCTTGAACTCTGTTAG Q|228|H silent|CAG>CAA|Q|228 D|229|H D|229|N SPC34 Spindle Pole Component 295.0 0 0 0 0 0.6647340645468731 P36131 0.09496530890464784 0.11163485795259476 0.4371683895587921 48.80113987812581 45.0 0.0 no 7687 chrXI_511132 22304 essential YKR037C 646 - TGGCCATAAATCTGTTACTT W|221|C W|221|* W|221|S W|221|* SPC34 Spindle Pole Component 295.0 0 0 0 0 -0.0823541058914582 P36131 0.008940864354372025 0.013450104743242264 44.38086369058647 35.0 0.0 no 7688 chrXI_511135r 22305 essential YKR037C 640 + TGGCCGAAGTAACAGATTTA A|215|G A|215|V silent|GCC>GCG|A|215 silent|GCC>GCT|A|215 SPC34 Spindle Pole Component 295.0 0 0 0 0 0.3827698117326598 P36131 0.34620434045791626 0.2578262388706207 43.60022540353282 40.0 0.0 no 7689 chrXI_511254r 22307 essential YKR037C 521 + TCAAAGGCTCCTATATGCCT Q|175|E Q|175|* SPC34 Spindle Pole Component 295.0 0 0 0 0 -0.2962902338796611 P36131 0.9885671138763428 51.09359172729461 45.0 0.0 no 7690 chrXI_511322r 22311 essential YKR037C 453 + GTCATTTCAAATTCAAGTTC silent|GTC>GTG|V|152 silent|GTC>GTT|V|152 SPC34 Spindle Pole Component 295.0 0 0 0 0 0.6354100491883683 P36131 38.439748475530045 30.0 0.0 no 7691 chrXI_511461r 22314 essential YKR037C 314 + ACCGATCATCCATGTGCCCA P|106|R P|106|L P|106|A P|106|S SPC34 Spindle Pole Component 295.0 0 0 0 0 0.1365694303994701 P36131 0.0 0.0 0.0 0.0 58.531239185037464 55.00000000000001 0.0 no 7692 chrXI_511674 22318 essential YKR037C 104 - CCTTGTTGCTTGCTCCCTGT K|41|N silent|AAG>AAA|K|41 SPC34 Spindle Pole Component 295.0 0 0 0 0 -5.990460040853982 P36131 0.5148099660873413 62.6813381809173 55.00000000000001 0.0 yes 7693 chrXI_511688r 22319 essential YKR037C 87 + TTTCATAATGCCATCCTACA H|31|D H|31|Y SPC34 Spindle Pole Component 295.0 0 0 0 0 0.02214071537334117 P36131 0.038480378687381744 0.0532316155731678 46.55685275258179 35.0 0.0 no 7694 chrXI_511638r 22320 essential YKR037C 137 + AGACATTACTAGACTAATAA D|47|E silent|GAC>GAT|D|47 SPC34 Spindle Pole Component 295.0 0 0 0 0 -1.4186752030622172 P36131 1.0 33.34524583604877 25.0 0.0 no 7695 chrXI_511715r 22322 essential YKR037C 60 + ACACTCTATTTCAAGCCACC L|22|V L|22|F T|21|R T|21|I SPC34 Spindle Pole Component 295.0 0 0 0 0 0.562590091255912 P36131 0.06321064382791519 0.03576982766389847 0.13014404475688934 0.06631285697221756 49.9119856593166 45.0 0.0 no 7696 chrXI_512275 22323 essential YKR038C 865 - TTCTGTTATTTCAACTAGCA E|295|Q E|295|K KAE1 Kinase-Associated Endopeptidase 386.0 0 0 0 0 0.3273505821165216 P36132 0.956179976463318 0.9475290179252625 0.0 0.0 42.440240859909245 30.0 0.0 no 7697 chrXI_512453 22327 essential YKR038C 687 - TCCATCCCCTTTACTGTATA M|235|I M|235|I D|236|H D|236|N KAE1 Kinase-Associated Endopeptidase 386.0 0 0 0 0 -1.7437408038168662 P36132 0.9553959965705872 0.9553959965705872 0.9486550092697144 0.956179976463318 0.011751176789402962 0.011751176789402962 0.004434117581695318 0.05211478844285011 1.2058000564575195 1.2058000564575195 53.28201233614601 40.0 0.0 no 7698 chrXI_512458r 22328 essential YKR038C 679 + AACTTCCCTATACAGTAAAG L|228|V L|228|F P|229|A P|229|S KAE1 Kinase-Associated Endopeptidase 386.0 0 0 0 0 0.32849406586099306 P36132 0.9512209892272948 0.9587849974632264 0.9562489986419678 0.9498909711837769 0.010371743701398373 0.0362309105694294 0.0 0.0 2.200599908828736 -0.4997999966144562 40.613195493401115 35.0 0.0 no 7699 chrXI_512481 22329 essential YKR038C 659 - CTACCAAGTTTTCTTTGTGA V|226|L V|226|I L|225|F silent|TTG>TTA|L|225 KAE1 Kinase-Associated Endopeptidase 386.0 0 0 0 0 0.9080618818824036 P36132 0.9539830088615416 0.9574310183525084 0.9587849974632264 0.4530209302902222 1.0 0.3744383752346039 -0.6384000182151794 -0.9296000003814696 1.688599944114685 45.00107818908145 35.0 0.0 no 7700 chrXI_512459r 22330 essential YKR038C 678 + GAACTTCCCTATACAGTAAA L|228|V L|228|F P|229|A P|229|S KAE1 Kinase-Associated Endopeptidase 386.0 0 0 0 0 -0.3235627008455197 P36132 0.9512209892272948 0.9587849974632264 0.9562489986419678 0.9498909711837769 0.010371743701398373 0.0362309105694294 0.0 0.0 2.200599908828736 -0.4997999966144562 41.724218218754906 35.0 0.0 no 7701 chrXI_512522 22333 essential YKR038C 618 - TCGATGTTGTAGCCAGGCGA E|213|Q E|213|K KAE1 Kinase-Associated Endopeptidase 386.0 0 0 0 0 -1.989885170963136 P36132 0.956179976463318 0.9475290179252625 0.011589608155190943 0.009085165336728096 1.1477999687194824 1.1122000217437744 54.63985385052752 55.00000000000001 0.0 no 7702 chrXI_512534r 22335 essential YKR038C 603 + ATACCTAATGAGCCCTCGCC P|203|A P|203|S P|203|R P|203|L KAE1 Kinase-Associated Endopeptidase 386.0 0 0 0 0 0.2396471880502788 P36132 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.6039164662361145 1.0 0.2059917449951172 0.15826231241226196 55.88766471867467 55.00000000000001 0.0 no 7703 chrXI_512637r 22336 essential YKR038C 500 + TACACAAGTTATTGCATACT T|168|R T|168|I Q|169|E Q|169|* KAE1 Kinase-Associated Endopeptidase 386.0 0 0 0 0 -0.3002401651814404 P36132 0.9476869702339172 0.9472420215606691 0.9590039849281312 0.0014529689215123653 0.001666074269451201 0.0 39.87688601032744 30.0 0.0 no 7704 chrXI_512666 22337 essential YKR038C 474 - CCACTTACATACAGTACCAC S|164|T S|164|N G|165|R G|165|S KAE1 Kinase-Associated Endopeptidase 386.0 0 1 0 0 -3.529580767246645 P36132 0.9512869715690612 0.9536849856376648 0.941340982913971 0.951104998588562 0.0 0.0 0.031640615314245224 0.007335168775171042 47.35745092846258 45.0 0.0 yes 7705 chrXI_512714r 22339 essential YKR038C 423 + TGCATTGGTCACATCGAAAT C|142|W silent|TGC>TGT|C|142 KAE1 Kinase-Associated Endopeptidase 386.0 0 1 0 0 -1.3626101180681387 P36132 0.9286419749259948 0.0008323874208144844 43.82485233212367 40.0 0.0 no 7706 chrXI_512718 22340 essential YKR038C 422 - TTTCGATGTGACCAATGCAG E|147|Q E|147|K KAE1 Kinase-Associated Endopeptidase 386.0 0 1 0 0 -7.178523770469573 P36132 0.956179976463318 0.9475290179252625 0.0 0.0 -3.2223999500274663 -2.2881999015808105 45.92430323207259 45.0 0.0 yes 7707 chrXI_512764r 22344 essential YKR038C 373 + CCAGAACGTGCTCCTTACTG silent|GCC>GCG|A|125 silent|GCC>GCT|A|125 T|127|R T|127|M KAE1 Kinase-Associated Endopeptidase 386.0 0 0 0 0 0.549539139353999 P36132 0.9476869702339172 0.9502379894256592 0.00487916124984622 0.13840024173259735 52.05345546058442 55.00000000000001 0.0 no 7708 chrXI_512844 22349 essential YKR038C 296 - TTACATCAATGTCTAGTGTC V|105|L V|105|I D|104|H D|104|N KAE1 Kinase-Associated Endopeptidase 386.0 0 0 0 0 -0.5119358232194418 P36132 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 0.8609070777893066 0.4995884895324707 0.004963523708283901 0.019763555377721783 42.10398941328509 35.0 0.0 no 7709 chrXI_512958r 22351 essential YKR038C 179 + CACATATGTCACACCTCCTG T|61|R T|61|I KAE1 Kinase-Associated Endopeptidase 386.0 0 1 0 0 -1.3764374773618802 P36132 0.9476869702339172 0.9472420215606691 0.002592489356175065 0.0053894505836069575 51.013228604952246 50.0 0.0 no 7710 chrXI_512959r 22352 essential YKR038C 178 + ACACATATGTCACACCTCCT T|61|R T|61|I D|60|E silent|GAC>GAT|D|60 KAE1 Kinase-Associated Endopeptidase 386.0 0 1 0 0 0.10109854142622583 P36132 0.9476869702339172 0.9472420215606691 0.9532920122146606 0.002592489356175065 0.0053894505836069575 1.0 51.5223434277761 45.0 0.0 no 7711 chrXI_512960r 22353 essential YKR038C 177 + GACACATATGTCACACCTCC D|60|E silent|GAC>GAT|D|60 T|61|R T|61|I KAE1 Kinase-Associated Endopeptidase 386.0 0 1 0 0 0.001992360711898622 P36132 0.9532920122146606 0.9476869702339172 0.9472420215606691 1.0 0.002592489356175065 0.0053894505836069575 50.921094829979154 50.0 0.0 no 7712 chrXI_513013 22354 essential YKR038C 127 - ATCATAAGATAGATCGCTGT D|49|H D|49|N KAE1 Kinase-Associated Endopeptidase 386.0 0 0 0 0 -1.7983514350875052 P36132 0.9486550092697144 0.956179976463318 0.03559089079499245 0.23110640048980716 41.60702667340354 35.0 0.0 no 7713 chrXI_513068r 22355 essential YKR038C 69 + TCTGCAAATAAACTGGGCGT S|24|C S|24|F A|25|G A|25|V KAE1 Kinase-Associated Endopeptidase 386.0 0 0 0 0 -2.2613008082367205 P36132 0.945252001285553 0.9294660091400146 0.9484469890594482 0.9504740238189696 0.001556707196868956 0.0007811886025592685 0.0 0.0 -1.5534000396728516 0.13339999318122864 44.78406968704229 45.0 0.0 yes 7714 chrXI_513092r 22356 essential YKR038C 45 + TACATTGCGCTTGGACTTGA Y|16|* silent|TAC>TAT|Y|16 KAE1 Kinase-Associated Endopeptidase 386.0 0 0 0 0 0.8206194111935428 P36132 48.53617824340034 45.0 0.0 no 7715 chrXI_513125r 22358 essential YKR038C 12 + AACACTATCCCACCCAAAAA N|5|K silent|AAC>AAT|N|5 T|6|S T|6|I KAE1 Kinase-Associated Endopeptidase 386.0 0 0 0 0 1.4466744896024877 P36132 0.9439849853515624 0.9491789937019348 0.9472420215606691 44.5257360333614 40.0 0.0 no 7716 chrXI_559684r 22359 essential YKR062W 21 - GCGTTCAAATTAGCCAGTAG A|14|P A|14|T L|12|F silent|TTG>TTA|L|12 TFA2 Transcription Factor a, subunit 2 328.0 0 0 0 0 -0.2348985178179721 P36145 0.9573720097541808 0.9523990154266356 0.9587849974632264 46.78497774551739 45.0 1.0 no 7717 chrXI_559744r 22362 essential YKR062W 81 - TTCTTCTGTCCAACTTTAGC K|33|N silent|AAG>AAA|K|33 Q|32|H silent|CAG>CAA|Q|32 TFA2 Transcription Factor a, subunit 2 328.0 0 0 0 0 0.218253842619186 P36145 0.9355990290641784 0.9570760130882264 48.7028198345277 40.0 1.0 no 7718 chrXI_559745r 22363 essential YKR062W 82 - CTTCTTCTGTCCAACTTTAG K|33|N silent|AAG>AAA|K|33 Q|32|H silent|CAG>CAA|Q|32 TFA2 Transcription Factor a, subunit 2 328.0 0 0 0 0 -2.137119326886745 P36145 0.9355990290641784 0.9570760130882264 46.71432021221561 40.0 1.0 yes 7719 chrXI_559851 22365 essential YKR062W 185 + TGCGAAAAATCCTGTGTTAG A|63|G A|63|V TFA2 Transcription Factor a, subunit 2 328.0 0 0 0 0 0.97432364618275 P36145 0.9484469890594482 0.9504740238189696 0.39530086517333984 0.32573917508125305 40.993872357756686 40.0 1.0 no 7720 chrXI_559861r 22366 essential YKR062W 198 - TTCTTGATATCCACTAACAC K|72|N silent|AAG>AAA|K|72 TFA2 Transcription Factor a, subunit 2 328.0 0 0 0 0 0.2904758106326785 P36145 0.9355990290641784 0.11759702116250992 41.752384295964646 35.0 1.0 no 7721 chrXI_560214 22370 essential YKR062W 548 + CTACGATGTCCATTCCCCTT Y|184|* silent|TAC>TAT|Y|184 TFA2 Transcription Factor a, subunit 2 328.0 0 1 0 0 -0.9351936454302764 P36145 56.26109148343585 50.0 1.0 no 7722 chrXI_560230r 22372 essential YKR062W 567 - AACAACTTCAGCAGTTCCGA L|195|F silent|TTG>TTA|L|195 K|194|N silent|AAG>AAA|K|194 TFA2 Transcription Factor a, subunit 2 328.0 0 0 0 0 -2.7401030802075823 P36145 0.9587849974632264 0.9355990290641784 1.0 0.5052383542060852 47.78797867271214 45.0 1.0 yes 7723 chrXI_560282r 22374 essential YKR062W 619 - ACCGTCTTTCAAGTCTTTGC G|213|R G|213|S G|213|A G|213|D TFA2 Transcription Factor a, subunit 2 328.0 0 0 0 0 0.16030755912504202 P36145 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 51.18228326558784 45.0 1.0 no 7724 chrXI_561604r 22378 essential YKR063C 671 + TACAAGTAGTAACTTTTCTG T|225|R T|225|I LAS1 Lethal in the Absence of SSD1-v 502.0 0 0 0 0 0.9148597764525472 P36146 0.011959429830312729 0.013112538494169712 37.044489090782974 30.0 0.0 no 7725 chrXI_561667r 22380 essential YKR063C 608 + GCGACTTAGAAACGAGTTTC R|204|G R|204|* L|205|V L|205|F LAS1 Lethal in the Absence of SSD1-v 502.0 0 0 0 0 0.15556662071665694 P36146 0.41430529952049255 0.6517436504364014 0.7631498575210571 42.597337407717305 45.0 0.0 no 7726 chrXI_561692r 22381 essential YKR063C 583 + TAACTAAAACACTTGATAAA T|196|S T|196|I LAS1 Lethal in the Absence of SSD1-v 502.0 0 0 0 0 0.5804629828261885 P36146 0.6463337540626526 0.13398918509483335 28.559917950685808 20.0 0.0 no 7727 chrXI_561833 22382 essential YKR063C 445 - TAGCCAAGATAACGCTTCAT W|154|C W|154|* W|154|S W|154|* LAS1 Lethal in the Absence of SSD1-v 502.0 0 0 0 0 -0.6966730543749386 P36146 0.0 0.0 44.894592932910825 40.0 0.0 no 7728 chrXI_561861 22384 essential YKR063C 417 - CAACGAAGCATTTCTAATCC R|145|P R|145|H LAS1 Lethal in the Absence of SSD1-v 502.0 0 0 0 0 -1.0573638134757108 P36146 0.0 0.0 41.72247676559283 40.0 0.0 no 7729 chrXI_562043r 22388 essential YKR063C 232 + ATCAGGATTCTATTCCTATC Q|79|E Q|79|* LAS1 Lethal in the Absence of SSD1-v 502.0 0 0 0 0 -0.9629144971808372 P36146 1.0 45.057459586638004 35.0 0.0 no 7730 chrXI_562071r 22391 essential YKR063C 204 + GACGAAAAGGAAGCGTGTTT D|69|E silent|GAC>GAT|D|69 LAS1 Lethal in the Absence of SSD1-v 502.0 0 0 0 0 0.522898544221565 P36146 0.0 41.72445719339282 45.0 0.0 no 7731 chrXI_562129r 22393 essential YKR063C 146 + CCAATATTTACCTCACGTGG Q|50|E Q|50|* LAS1 Lethal in the Absence of SSD1-v 502.0 0 0 0 0 0.09984960158692692 P36146 0.05901678651571274 47.08950379089345 45.0 0.0 no 7732 chrXI_562119 22394 essential YKR063C 159 - GCTGTAGAGTCCACCACGTG A|60|P A|60|T LAS1 Lethal in the Absence of SSD1-v 502.0 0 0 0 0 -0.20773975136892164 P36146 0.02296951040625572 0.024633325636386868 56.65116060044653 60.0 0.0 no 7733 chrXI_570513r 22400 essential YKR068C 374 + TGACTTTGTGGAGTTACCCA D|126|E silent|GAC>GAT|D|126 BET3 Blocked Early in Transport 193.0 0 0 0 0 -0.3106795523859329 P36149 0.6905392408370972 51.18750298264359 45.0 0.0 no 7734 chrXI_570521 22401 essential YKR068C 369 - AACTCCACAAAGTCAGCCAA E|129|D silent|GAG>GAA|E|129 E|129|Q E|129|K BET3 Blocked Early in Transport 193.0 0 0 0 0 0.0013711876912202436 P36149 0.07275323569774628 0.016028283163905144 0.012282350100576878 0.313400000333786 0.02449999749660492 -0.08579999208450317 46.8838638156784 45.0 0.0 no 7735 chrXI_570522 22402 essential YKR068C 368 - ACTCCACAAAGTCAGCCAAT E|129|Q E|129|K E|129|D silent|GAG>GAA|E|129 BET3 Blocked Early in Transport 193.0 0 0 0 0 -0.2632805682439568 P36149 0.016028283163905144 0.012282350100576878 0.07275323569774628 0.02449999749660492 -0.08579999208450317 0.313400000333786 48.3827707503396 45.0 0.0 no 7736 chrXI_570525r 22403 essential YKR068C 362 + AAACCCATTGGCTGACTTTG N|122|K silent|AAC>AAT|N|122 P|123|A P|123|S BET3 Blocked Early in Transport 193.0 0 0 0 0 0.5493235417849238 P36149 0.0047458731569349774 0.0 0.0 1.528333306312561 2.525066614151001 47.512349063526294 45.0 0.0 no 7737 chrXI_570586r 22405 essential YKR068C 301 + TCACACCCAACATAACGAAC T|102|R T|102|I I|101|M silent|ATC>ATT|I|101 BET3 Blocked Early in Transport 193.0 0 0 0 0 0.20404184420478105 P36149 0.03571472316980362 0.03630521148443222 0.007941941730678082 -0.03858000040054321 -0.557200014591217 42.951202536453145 45.0 0.0 no 7738 chrXI_570581 22406 essential YKR068C 309 - TGCGACCAGTTCGTTATGTT silent|TCG>TCC|S|109 silent|TCG>TCA|S|109 W|108|C W|108|* BET3 Blocked Early in Transport 193.0 0 0 0 0 0.3326118513638178 P36149 0.13096022605895996 4.272079944610597 50.9391988504799 45.0 0.0 no 7739 chrXI_570656 22407 essential YKR068C 234 - TTCACTAAATTCTCACAGCG silent|GTG>GTC|V|84 silent|GTG>GTA|V|84 V|84|L V|84|M BET3 Blocked Early in Transport 193.0 0 0 0 1 0.8695911559712708 P36149 0.049925949424505234 0.017495229840278625 -0.4143199920654297 -0.4669800102710724 42.57645696015903 40.0 0.0 no 7740 chrXI_570853 22409 essential YKR068C 37 - TTTCCAGATCTCTTCTCCCA W|18|C W|18|* W|18|S W|18|* BET3 Blocked Early in Transport 193.0 0 0 0 0 -1.2259371636222374 P36149 0.008962873369455338 0.08610742539167404 1.3046000003814695 1.0587999820709229 56.38992601948286 45.0 0.0 no 7741 chrXI_570876r 22413 essential YKR068C 11 + CACGCAATCGAGGTCTTTGA T|5|R T|5|M Q|6|E Q|6|* BET3 Blocked Early in Transport 193.0 0 0 0 0 -0.7925978606700702 P36149 0.5661417245864868 0.0623537190258503 1.0 48.409916329841394 50.0 0.0 no 7742 chrXI_570877 22414 essential YKR068C 13 - CTTCAAAGACCTCGATTGCG L|10|F silent|TTG>TTA|L|10 BET3 Blocked Early in Transport 193.0 0 1 0 0 0.5396016022794605 P36149 0.3723677098751068 46.31905088514071 50.0 0.0 no 7743 chrXI_575175r 22415 essential YKR071C 783 + GCTTGTAAAGATTGCACCTG A|262|G A|262|V DRE2 Derepressed for Ribosomal protein S14 Expression 348.0 0 1 0 0 0.6925198944111851 P36152 0.0 0.0 46.42487277760239 45.0 0.0 no 7744 chrXI_575282 22416 essential YKR071C 679 - TTCTTCAATGGAATCATCGC E|233|Q E|233|K E|232|Q E|232|K DRE2 Derepressed for Ribosomal protein S14 Expression 348.0 0 1 0 0 -0.6139596578401222 P36152 0.0 0.0 0.4313237071037293 0.6515601277351379 43.57792692747205 40.0 0.0 no 7745 chrXI_575356 22417 essential YKR071C 605 - CATCATCGCTATCCTCAATC D|208|H D|208|N D|207|H D|207|N DRE2 Derepressed for Ribosomal protein S14 Expression 348.0 0 1 0 0 0.5077990868869768 P36152 0.18536652624607086 0.768115758895874 0.18936458230018616 0.94045227766037 48.33144496131053 45.0 0.0 no 7746 chrXI_575382 22419 essential YKR071C 579 - TCTACGACTCGGTAGACTTT D|200|H D|200|N V|199|L V|199|I DRE2 Derepressed for Ribosomal protein S14 Expression 348.0 0 0 0 0 0.6618826936042808 P36152 0.013808502815663816 0.03630015999078751 0.7084661722183228 0.4700910449028015 47.271672430854146 45.0 0.0 no 7747 chrXI_575465r 22422 essential YKR071C 493 + TCAAAAAAGCAGATCACAGT F|165|L silent|TTC>TTT|F|165 DRE2 Derepressed for Ribosomal protein S14 Expression 348.0 0 1 0 0 0.4474941046400875 P36152 0.0 37.30060369131093 35.0 0.0 no 7748 chrXI_575700 22424 essential YKR071C 261 - AAACCAATTAGTGAGCCGTT G|93|A G|93|D G|93|R G|93|S DRE2 Derepressed for Ribosomal protein S14 Expression 348.0 0 0 0 0 0.11693876591619798 P36152 0.0 0.0 0.0 0.0 2.6695001125335693 5.977680206298827 13.119959831237793 2.649399995803833 45.26788465163543 40.0 0.0 no 7749 chrXI_575703r 22425 essential YKR071C 255 + AAACCAAACGGCTCACTAAT P|87|A P|87|S P|87|R P|87|L DRE2 Derepressed for Ribosomal protein S14 Expression 348.0 0 0 0 0 -0.6105169340005254 P36152 0.7888610363006592 0.8044652938842773 0.5261616706848145 0.32510441541671753 1.131119966506958 1.0352400541305542 1.176419973373413 1.123520016670227 41.30229521796497 40.0 0.0 no 7750 chrXI_575758 22426 essential YKR071C 203 - TCGGAAACTTAATATCAGTC silent|CCG>CCC|P|74 silent|CCG>CCA|P|74 DRE2 Derepressed for Ribosomal protein S14 Expression 348.0 0 0 0 0 0.16388526316043014 P36152 37.97949215442196 35.0 0.0 no 7751 chrXI_575869r 22427 essential YKR071C 89 + ATCAAAGAAAGTCAAGTTCG S|31|* S|31|L DRE2 Derepressed for Ribosomal protein S14 Expression 348.0 0 0 0 0 -2.313280525731184 P36152 0.3692586123943329 -0.7036600112915039 35.66541112580916 35.0 0.0 yes 7752 chrXI_580040 22429 no_effect YKR075C 691 - GTCGATCTCCCTCTTCATCA D|237|H D|237|N E|235|D silent|GAG>GAA|E|235 0 0 0 0 -0.4095850498849043 P36155 0.9486550092697144 0.956179976463318 0.94931298494339 0.007201448082923889 0.03729233145713806 1.0 56.67572847235334 50.0 0.0 no 7753 chrXI_580045 22430 no_effect YKR075C 686 - TCTCCCTCTTCATCACGGCT E|235|Q E|235|K E|235|D silent|GAG>GAA|E|235 0 0 0 0 0.192669304427105 P36155 0.956179976463318 0.9475290179252625 0.94931298494339 0.11433275789022446 0.10563737154006958 1.0 60.046314828755435 55.00000000000001 0.0 no 7754 chrXI_580048r 22431 no_effect YKR075C 680 + TAACCAAGCCGTGATGAAGA N|228|K silent|AAC>AAT|N|228 Q|229|E Q|229|* 0 0 0 0 0.1801923429228897 P36155 0.9439849853515624 0.9590039849281312 0.2308367639780045 0.3004484176635742 44.685035809135115 45.0 0.0 no 7755 chrXI_580093 22432 no_effect YKR075C 638 - GTTCCTTCTTTTCGTTCATA E|219|Q E|219|K K|218|N silent|AAG>AAA|K|218 0 0 0 0 0.479878192856661 P36155 0.956179976463318 0.9475290179252625 0.9355990290641784 0.5666131377220154 0.8797774314880371 0.5483443737030029 49.59813525763667 35.0 0.0 no 7756 chrXI_580118 22433 no_effect YKR075C 613 - TTCAGAATCTTCATCTATGG E|211|Q E|211|K 0 0 0 0 -0.14763935193609307 P36155 0.956179976463318 0.9475290179252625 0.5820964574813843 0.9074538350105286 41.379708234215 35.0 0.0 no 7757 chrXI_580403 22436 no_effect YKR075C 328 - ACCGTACAACACCGTTACAT G|116|R G|116|S G|116|A G|116|D 0 0 0 0 0.5182664005061168 P36155 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 47.85902374376553 45.0 0.0 no 7758 chrXI_580414r 22438 no_effect YKR075C 314 + GAACAAAGAAACCGATGTAA N|106|K silent|AAC>AAT|N|106 0 0 0 0 0.06266364600876283 P36155 0.9439849853515624 0.011041826568543913 34.84563297097611 35.0 0.0 no 7759 chrXI_580436r 22440 no_effect YKR075C 292 + CCAATCCACTGTCCATCAAC silent|TCC>TCG|S|98 silent|TCC>TCT|S|98 P|100|A P|100|S 0 0 0 0 -0.15919158657415874 P36155 0.9562489986419678 0.9498909711837769 0.0 0.0 50.79872004986817 50.0 0.0 no 7760 chrXI_580696 22445 no_effect YKR075C 35 - TATCCAGTAACATTATATTC D|18|H D|18|N silent|CTG>CTC|L|17 silent|CTG>CTA|L|17 0 0 0 0 0.07187482585125407 P36155 0.9486550092697144 0.956179976463318 0.004657090175896883 0.012825625017285349 37.33015866353281 25.0 0.0 no 7761 chrXI_580636 22446 no_effect YKR075C 95 - TTGCATCATTAAATTCATGA A|38|P A|38|T D|37|H D|37|N 0 0 0 0 0.24610305473172625 P36155 0.9573720097541808 0.9523990154266356 0.9486550092697144 0.956179976463318 0.25732317566871643 0.4781466424465179 0.5615113973617554 0.5262218713760376 37.350384662048384 25.0 0.0 no 7762 chrXI_587451r 22449 essential YKR079C 1832 + GCAGACACAATCTGTTCCTT Q|612|E Q|612|* T|613|R T|613|I TRZ1 tRNase Z 838.0 0 0 0 0 -0.002504776206705972 P36159 1.0 0.6439492106437683 0.2527124285697937 50.06304872308328 45.0 0.0 no 7763 chrXI_587567 22450 essential YKR079C 1719 - ACAAATTTGTGATATTGCCA V|580|L V|580|I TRZ1 tRNase Z 838.0 0 0 0 0 0.7509656683662156 P36159 0.8034915328025818 0.8952461481094359 40.87677864203568 30.0 0.0 no 7764 chrXI_587649 22451 essential YKR079C 1637 - GCACGCTGATTATTCCCAAA V|552|L V|552|M silent|GTG>GTC|V|552 silent|GTG>GTA|V|552 TRZ1 tRNase Z 838.0 0 1 0 0 -0.2150385894000585 P36159 0.6674218773841858 0.2394312620162964 49.01179294996485 45.0 0.0 no 7765 chrXI_587663r 22452 essential YKR079C 1620 + TTGCATGCAGACCACCATTT H|542|D H|542|Y TRZ1 tRNase Z 838.0 0 0 0 0 -1.0379807564319958 P36159 0.0 0.0 52.166698956568496 45.0 0.0 no 7766 chrXI_587652 22453 essential YKR079C 1634 - CGCTGATTATTCCCAAATGG S|551|T S|551|N TRZ1 tRNase Z 838.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.4409164296866696 P36159 0.0 0.0 46.237645499502385 45.0 0.0 no 7767 chrXI_587712r 22454 essential YKR079C 1571 + AGCAGTCAAGTCAATATTTC A|525|G A|525|V silent|GTC>GTG|V|526 silent|GTC>GTT|V|526 TRZ1 tRNase Z 838.0 0 0 0 0 -0.42724457393485904 P36159 0.4460935592651367 0.2368791848421097 41.7279849188866 35.0 0.0 no 7768 chrXI_587797 22456 essential YKR079C 1489 - TCTATTTATGGTATTTCCAT R|503|T R|503|K TRZ1 tRNase Z 838.0 0 0 0 0 0.4010246406970516 P36159 0.0 0.0 42.35499323129318 25.0 0.0 no 7769 chrXI_587810 22457 essential YKR079C 1476 - TTTCCATCGGCGTCAGTAAA G|498|A G|498|E G|498|R G|498|R TRZ1 tRNase Z 838.0 0 0 0 0 0.7372312969981081 P36159 0.051418595016002655 0.039861146360635764 0.02125222235918045 0.02125222235918045 48.97971052203246 45.0 0.0 no 7770 chrXI_587813r 22458 essential YKR079C 1470 + GTTCCTTTTACTGACGCCGA P|492|A P|492|S P|492|R P|492|L TRZ1 tRNase Z 838.0 0 0 0 0 -0.2946550056943843 P36159 0.0 0.0 0.0 0.0 53.51132320213964 50.0 0.0 no 7771 chrXI_587852 22459 essential YKR079C 1434 - ACAACGTTTCTATATTTAGA V|485|L V|485|I V|484|L V|484|I TRZ1 tRNase Z 838.0 0 0 0 0 1.350122451439327 P36159 0.7158312201499939 1.0 0.0 0.0 37.17856113968821 25.0 0.0 no 7772 chrXI_587946r 22460 essential YKR079C 1337 + TATCAATAATCAACTACACG I|447|M silent|ATC>ATT|I|447 TRZ1 tRNase Z 838.0 0 0 0 0 1.1898727827478246 P36159 0.16977937519550326 34.305849168397685 30.0 0.0 no 7773 chrXI_587968 22461 essential YKR079C 1318 - AACTGTATCGACATCAGCTA V|446|L V|446|I TRZ1 tRNase Z 838.0 0 0 0 0 0.09475219144047342 P36159 0.7118065357208252 0.4683072865009308 44.38821108286624 40.0 0.0 no 7774 chrXI_587891r 22462 essential YKR079C 1392 + CACGTTGAAATTATCACCTT H|465|Q silent|CAC>CAT|H|465 TRZ1 tRNase Z 838.0 0 0 0 0 0.09603933799671008 P36159 0.6396999955177307 41.74326499390139 35.0 0.0 no 7775 chrXI_587969 22463 essential YKR079C 1317 - ACTGTATCGACATCAGCTAA V|446|L V|446|I TRZ1 tRNase Z 838.0 0 0 0 0 0.6847903483423903 P36159 0.7118065357208252 0.4683072865009308 44.388211082866285 40.0 0.0 no 7776 chrXI_587981 22464 essential YKR079C 1305 - TCAGCTAAGGGAAATTCTAA D|442|H D|442|N A|441|P A|441|T TRZ1 tRNase Z 838.0 0 0 0 0 -0.6730183246840562 P36159 0.225981280207634 0.5952491164207458 0.280178427696228 0.6958436369895935 39.1812002266185 35.0 0.0 no 7777 chrXI_588053 22465 essential YKR079C 1233 - CCGTTGATGTTGCATTTCAT G|418|R G|418|S TRZ1 tRNase Z 838.0 0 0 0 0 0.17795441719411306 P36159 0.08598080277442932 1.0 48.79828808134046 40.0 0.0 no 7778 chrXI_588053r 22467 essential YKR079C 1230 + CCGATGAAATGCAACATCAA P|411|R P|411|L TRZ1 tRNase Z 838.0 0 0 0 0 -0.4799595347415006 P36159 0.5488395094871521 0.5213634371757507 40.32821354300319 40.0 0.0 no 7779 chrXI_588143 22468 essential YKR079C 1143 - TTCTCTATTATTGTATTCAA E|387|D silent|GAG>GAA|E|387 E|387|Q E|387|K TRZ1 tRNase Z 838.0 0 0 0 0 -0.9095317974868588 P36159 0.6082735061645508 0.5330722332000732 0.8133640885353088 37.08419122978216 20.0 0.0 no 7780 chrXI_588171r 22469 essential YKR079C 1112 + TACATCTATGTGTAAATCCC T|372|R T|372|I S|373|C S|373|F TRZ1 tRNase Z 838.0 0 0 0 0 -0.3143655346194152 P36159 42.80994882995623 35.0 0.0 no 7781 chrXI_588194r 22470 essential YKR079C 1089 + TTCGATACACCACTCAGCAG F|364|L silent|TTC>TTT|F|364 TRZ1 tRNase Z 838.0 0 0 0 0 1.075837455382004 P36159 0.2962687015533447 49.290547737439965 50.0 0.0 no 7782 chrXI_588231r 22471 essential YKR079C 1052 + AACAGATCGTGTGTTTTCCA T|352|R T|352|I TRZ1 tRNase Z 838.0 0 0 0 0 -0.2516506159017289 P36159 0.28334060311317444 0.18975666165351868 47.459230551268774 40.0 0.0 no 7783 chrXI_588495 22476 essential YKR079C 791 - CTACGAAAGCGTTCAAATAT V|270|L V|270|I TRZ1 tRNase Z 838.0 0 0 0 0 -0.07067818366323575 P36159 0.6829299926757812 0.4286711513996124 37.665331816574046 35.0 0.0 no 7784 chrXI_588560 22478 essential YKR079C 726 - TCATTCTCCAATACCTGTTC E|249|Q E|249|K E|247|D silent|GAG>GAA|E|247 TRZ1 tRNase Z 838.0 0 0 0 0 -0.4243569408727139 P36159 0.5312451124191284 0.8622000217437744 0.5563325881958008 48.63715754069642 40.0 0.0 no 7785 chrXI_588680 22479 essential YKR079C 606 - ACTTTAAATTTACCCCTCAC V|209|L V|209|M TRZ1 tRNase Z 838.0 0 0 0 0 0.36183574995198203 P36159 0.773271381855011 0.18079984188079834 44.903069337577904 35.0 0.0 no 7786 chrXI_588721 22480 essential YKR079C 565 - ATTCGTAGAAACTTCCACTT silent|ACG>ACC|T|194 silent|ACG>ACA|T|194 TRZ1 tRNase Z 838.0 0 0 0 0 0.3172141336656469 P36159 43.136873332909545 35.0 0.0 no 7787 chrXI_588734 22481 essential YKR079C 552 - TCCACTTTGGCGTCTAAGTC silent|GTG>GTC|V|190 silent|GTG>GTA|V|190 E|191|Q E|191|K TRZ1 tRNase Z 838.0 0 0 0 0 0.9333705030991808 P36159 0.678039014339447 0.919037699699402 52.51818609222414 50.0 0.0 no 7788 chrXI_588767 22483 essential YKR079C 519 - TTCAAGTGCGGATCACTAGA L|179|F silent|TTG>TTA|L|179 TRZ1 tRNase Z 838.0 0 0 0 0 -0.031338950825827216 P36159 0.15434230864048004 46.61793959350706 45.0 0.0 no 7789 chrXI_588892 22489 essential YKR079C 394 - CCCATTTTTCAGAACATTAA G|138|R G|138|R G|138|A G|138|E TRZ1 tRNase Z 838.0 0 0 0 0 -0.7590939299779564 P36159 0.5370976924896239 0.5370976924896239 0.7733087539672852 1.0 41.449874182541976 30.0 0.0 no 7790 chrXI_588893r 22490 essential YKR079C 390 + TCCTTTAATGTTCTGAAAAA silent|TCC>TCG|S|131 silent|TCC>TCT|S|131 S|131|C S|131|F TRZ1 tRNase Z 838.0 0 0 0 0 0.03646999159110738 P36159 0.11234619468450546 0.2670159637928009 35.71643359609817 25.0 0.0 no 7791 chrXI_589116 22493 essential YKR079C 170 - ACCAGTTTAATTCACCAGTA W|63|S W|63|* W|63|C W|63|* TRZ1 tRNase Z 838.0 0 0 0 0 0.4092704744053317 P36159 0.0 0.0 46.06786997231097 35.0 0.0 no 7792 chrXI_589221 22495 essential YKR079C 65 - ACTTTTCCCCATGTGCAGAC K|28|N silent|AAG>AAA|K|28 E|27|Q E|27|K TRZ1 tRNase Z 838.0 0 0 0 0 -0.02959517812005497 P36159 0.019490532577037808 0.4473508596420288 0.7855307459831238 55.319886125951825 50.0 0.0 no 7793 chrXI_589229r 22497 essential YKR079C 54 + CTGCTAGTCCAGTCTGCACA L|20|V silent|CTA>TTA|L|20 TRZ1 tRNase Z 838.0 0 0 0 0 0.6058602562918494 P36159 0.95357483625412 57.77280323382485 55.00000000000001 0.0 no 7794 chrXI_591765 22500 essential YKR081C 756 - GTCTTCATTTCTAATTGTTT K|258|N silent|AAG>AAA|K|258 M|257|I M|257|I RPF2 Ribosome Production Factor 344.0 0 0 0 0 -0.24291533730481665 P36160 0.006805302109569311 0.21380603313446045 0.21380603313446045 41.38373122085886 25.0 0.0 no 7795 chrXI_591808r 22501 essential YKR081C 710 + TCATACTCCAAGTCCAGATA H|238|D H|238|Y T|239|S T|239|I RPF2 Ribosome Production Factor 344.0 0 0 0 0 0.14834453854176174 P36160 0.04886455088853836 0.061568345874547965 0.4675856232643128 0.11044715344905852 1.0496400594711304 -1.387539982795715 0.3033599853515625 -0.3021799921989441 47.33423417259132 40.0 0.0 no 7796 chrXI_591864 22504 essential YKR081C 657 - ATCTCCACCAATTCAATACG E|225|D silent|GAG>GAA|E|225 E|225|Q E|225|K RPF2 Ribosome Production Factor 344.0 0 0 0 0 -0.4778932746775595 P36160 0.0759294182062149 0.036918800324201584 0.03075509518384933 1.1632000207901 1.7992600202560425 1.8643200397491453 44.413672327702216 40.0 0.0 no 7797 chrXI_592011r 22506 essential YKR081C 507 + ACTGATTTACAGGATGTTGC T|170|S T|170|I RPF2 Ribosome Production Factor 344.0 0 0 0 0 -0.5859524371966256 P36160 0.4090997874736786 0.4151575267314911 0.4056200087070465 1.5380400419235232 44.508458013084066 40.0 0.0 no 7798 chrXI_592107r 22507 essential YKR081C 411 + AAGCCTATGTTTACATTCCA P|139|A P|139|S P|139|R P|139|L RPF2 Ribosome Production Factor 344.0 0 0 0 0 0.42344077207922265 P36160 0.0 0.0 0.0 0.0 1.8206199407577517 2.6373400688171387 3.869379997253418 3.1950199604034424 47.151945132456426 35.0 0.0 no 7799 chrXI_592419 22508 essential YKR081C 102 - TTCTTGTTACAGCTTTGCCC K|40|N silent|AAG>AAA|K|40 RPF2 Ribosome Production Factor 344.0 0 0 0 0 -0.3703380626566445 P36160 0.3959802687168121 0.3301999866962433 54.35508164297005 45.0 0.0 no 7800 chrXI_592437r 22510 essential YKR081C 81 + AAGCAAGCGCTATTCATTCC Q|29|E Q|29|* RPF2 Ribosome Production Factor 344.0 0 0 0 0 0.5807428136846995 P36160 0.40977224707603455 1.890220046043396 48.57469308425374 45.0 0.0 no 7801 chrXI_592499 22513 essential YKR081C 22 - TCTCTTGGCTCTTGCATTCT K|13|N silent|AAG>AAA|K|13 R|14|T R|14|K RPF2 Ribosome Production Factor 344.0 0 0 0 0 1.0856289743489465 P36160 0.02475845068693161 0.0 0.0 55.03619546348892 45.0 0.0 no 7802 chrXI_592500 22514 essential YKR081C 21 - CTCTTGGCTCTTGCATTCTT K|13|N silent|AAG>AAA|K|13 RPF2 Ribosome Production Factor 344.0 0 0 0 0 0.07150689531653666 P36160 0.02475845068693161 54.061255244971726 45.0 0.0 no 7803 chrXI_592508 22515 essential YKR081C 13 - TCTTGCATTCTTGGGTTTTA R|11|T R|11|K A|10|P A|10|T RPF2 Ribosome Production Factor 344.0 0 0 0 0 0.6870176978232208 P36160 0.005834333132952453 0.10971676558256148 0.15893866121768951 0.01920649968087673 48.40458497315638 35.0 0.0 no 7804 chrXI_592863 22516 high_effect YKR082W 38 + ACTTAGCGTACCCATTGCGG L|14|V L|14|F S|15|R silent|AGC>AGT|S|15 NUP133 NUclear Pore 1157.0 0 0 0 0 -0.1814630952750476 P36161 0.08265097439289093 0.040865514427423484 0.5043231844902039 54.417539855953635 55.00000000000001 1.0 no 7805 chrXI_592873r 22517 high_effect YKR082W 51 - TCGTTTTCAACCACCGCAAT E|24|Q E|24|K NUP133 NUclear Pore 1157.0 0 0 0 0 -0.5372629382299094 P36161 0.3751471042633057 0.5895400643348694 49.52483972317896 45.0 1.0 no 7806 chrXI_592935 22520 high_effect YKR082W 110 + CTCTCTAATGGACATTTCCA S|38|C S|38|F L|39|V silent|CTA>TTA|L|39 NUP133 NUclear Pore 1157.0 0 0 0 0 -0.7445408317995053 P36161 0.07686205208301544 0.12582218647003174 0.4277528524398804 46.60184475241954 40.0 1.0 no 7807 chrXI_592952r 22522 high_effect YKR082W 130 - CCTTAACTGTTGCTGCTCCA R|50|T R|50|K Q|48|H silent|CAG>CAA|Q|48 NUP133 NUclear Pore 1157.0 0 0 0 0 0.2824451489763739 P36161 0.5400230884552002 1.0 0.0928802490234375 55.15258176227115 50.0 1.0 no 7808 chrXI_593036r 22523 high_effect YKR082W 214 - GCTACTGTAGTCTGTTTGAA S|78|T S|78|N S|77|T S|77|N NUP133 NUclear Pore 1157.0 0 0 0 0 0.5521552771501712 P36161 0.7918185591697693 0.6558514237403871 0.2301034927368164 0.13090558350086212 46.65027273085097 40.0 1.0 no 7809 chrXI_593037r 22524 high_effect YKR082W 215 - CGCTACTGTAGTCTGTTTGA S|78|T S|78|N S|77|T S|77|N NUP133 NUclear Pore 1157.0 0 0 0 0 0.7521612145016057 P36161 0.7918185591697693 0.6558514237403871 0.2301034927368164 0.13090558350086212 49.528559385769036 45.0 1.0 no 7810 chrXI_593038 22525 high_effect YKR082W 213 + CTTCAAACAGACTACAGTAG Q|73|E Q|73|* NUP133 NUclear Pore 1157.0 0 0 0 0 0.04247588936329977 P36161 1.0 39.13751770225013 40.0 1.0 no 7811 chrXI_593115 22527 high_effect YKR082W 290 + ACTAGTCAATGACCACAAGA L|98|V silent|CTA>TTA|L|98 silent|GTC>GTG|V|99 silent|GTC>GTT|V|99 NUP133 NUclear Pore 1157.0 0 0 0 0 0.9050630966798552 P36161 0.05087379738688469 42.66682509343576 40.0 1.0 no 7812 chrXI_593126 22528 high_effect YKR082W 301 + ACCACAAGAAGGTTTACATC H|102|D H|102|Y D|101|E silent|GAC>GAT|D|101 NUP133 NUclear Pore 1157.0 0 0 0 0 -0.5616252979008238 P36161 0.3663581907749176 0.3499713540077209 0.0 42.545166676227545 40.0 1.0 no 7813 chrXI_593272r 22530 high_effect YKR082W 450 - TCATTAGGATTCAGTGCTAA D|157|H D|157|N NUP133 NUclear Pore 1157.0 0 0 0 0 0.4014670784147389 P36161 0.06119712442159653 0.6555444598197937 43.36544964606537 35.0 1.0 no 7814 chrXI_593277 22532 high_effect YKR082W 452 + AGCACTGAATCCTAATGATC A|152|G A|152|V L|153|V silent|CTG>TTG|L|153 NUP133 NUclear Pore 1157.0 0 0 0 0 0.23203237767571425 P36161 0.440678209066391 0.3710646629333496 1.0 42.9811605449961 40.0 1.0 no 7815 chrXI_593416 22535 high_effect YKR082W 591 + TTACCCATCAACTCTTCGGG P|199|A P|199|S P|199|R P|199|L NUP133 NUclear Pore 1157.0 0 0 0 0 0.16430683736076704 P36161 0.08061842620372772 0.06933324038982391 0.4596629142761231 0.06475751101970673 51.1765551371272 50.0 1.0 no 7816 chrXI_593632 22539 high_effect YKR082W 807 + TTACGAAATGGACCTATCCT R|271|G R|271|* NUP133 NUclear Pore 1157.0 0 0 0 0 -0.3429459938285032 P36161 0.019641296938061714 44.57429834303002 40.0 1.0 no 7817 chrXI_591916 22540 essential YKR081C 605 - AACTTTTTAATTTGTAAACA S|208|T S|208|N RPF2 Ribosome Production Factor 344.0 0 0 0 0 0.32377318313455405 P36160 1.0 0.3149819076061249 -0.6261399984359741 -0.063960000872612 31.01866114724521 15.0 0.0 no 7818 chrXI_593729r 22541 high_effect YKR082W 907 - ATCAATCAATTTTGTTGGAT D|309|H D|309|N L|307|F silent|TTG>TTA|L|307 NUP133 NUclear Pore 1157.0 0 0 0 0 0.8357688396756181 P36161 0.1995670646429062 0.16351348161697388 0.19031327962875366 37.95392695824728 25.0 1.0 no 7819 chrXI_593797r 22543 high_effect YKR082W 975 - TTCAACGTACCATGAGCAAA L|331|F silent|TTG>TTA|L|331 silent|ACG>ACC|T|330 silent|ACG>ACA|T|330 NUP133 NUclear Pore 1157.0 0 0 0 0 1.381177828688215 P36161 0.0 42.863123142041616 40.0 1.0 no 7820 chrXI_593730r 22544 high_effect YKR082W 908 - CATCAATCAATTTTGTTGGA D|309|H D|309|N NUP133 NUclear Pore 1157.0 0 0 0 0 0.3514342699482603 P36161 0.1995670646429062 0.16351348161697388 39.31082945244924 30.0 1.0 no 7821 chrXI_593865r 22545 high_effect YKR082W 1043 - AACTGTCGTAAATAGATGAC S|354|T S|354|N D|353|H D|353|N NUP133 NUclear Pore 1157.0 0 0 0 0 0.7482647015889803 P36161 0.4406388103961945 1.0 0.13020376861095428 0.4404026567935944 36.397856756150986 35.0 1.0 no 7822 chrXI_594565r 22548 high_effect YKR082W 1743 - ATCAGATCCAATTTCAGTTC silent|CTG>CTC|L|587 silent|CTG>CTA|L|587 NUP133 NUclear Pore 1157.0 0 0 0 0 1.0938920077915744 P36161 44.01653476699307 35.0 1.0 no 7823 chrXI_594566r 22549 high_effect YKR082W 1744 - GATCAGATCCAATTTCAGTT silent|CTG>CTC|L|587 silent|CTG>CTA|L|587 NUP133 NUclear Pore 1157.0 0 0 0 0 0.21306260668098853 P36161 44.258693254781925 35.0 1.0 no 7824 chrXI_594841 22550 high_effect YKR082W 2016 + ATCAACTTATGCTTTTATGA I|673|M silent|ATC>ATT|I|673 N|674|K silent|AAC>AAT|N|674 NUP133 NUclear Pore 1157.0 0 0 0 0 0.6151154880906786 P36161 0.06524874269962311 0.1216692104935646 38.828141888019 25.0 1.0 no 7825 chrXI_594885 22551 high_effect YKR082W 2060 + AACTATAAGGTATGAACTTT T|688|S T|688|I NUP133 NUclear Pore 1157.0 0 0 0 0 0.2419879861124721 P36161 0.7827296853065491 0.15548188984394073 34.56883614080135 25.0 1.0 no 7826 chrXI_594900 22552 high_effect YKR082W 2075 + ACTTTTGGAGTTAGACCCGA L|693|V L|693|F NUP133 NUclear Pore 1157.0 0 0 0 0 -0.006131167428685802 P36161 0.6339740753173828 0.7463468909263611 11.34980010986328 -0.42399999499320973 49.9062367010032 45.0 1.0 no 7827 chrXI_596530r 22556 essential YKR083C 270 + TCTGAACAATCAAATGAAAC S|91|C S|91|F Q|93|E Q|93|* DAD2 Duo1 And Dam1 interacting 133.0 0 0 0 0 0.3864979647563621 P36162 31.52010295226711 30.0 0.0 no 7828 chrXI_596651 22558 essential YKR083C 152 - AATCCCAATTGTTCATCAAT D|57|H D|57|N W|56|C W|56|* DAD2 Duo1 And Dam1 interacting 133.0 0 0 0 0 0.9752889459986802 P36162 0.025724450126290318 0.33060938119888306 0.0 0.3388800024986267 42.382144339265544 30.0 0.0 no 7829 chrXI_596747r 22560 essential YKR083C 53 + ACAAAAGATAACCAGTTTAA Q|19|E Q|19|* DAD2 Duo1 And Dam1 interacting 133.0 0 0 0 0 -0.15671353831114224 P36162 0.04488715901970863 33.447887284767035 25.0 0.0 no 7830 chrXI_594102 22561 high_effect YKR082W 1277 + TACTCAGGTGAACTCAAAAT T|427|S T|427|I Q|428|E Q|428|* NUP133 NUclear Pore 1157.0 0 0 0 0 0.9395125583680876 P36161 0.191492959856987 0.14246314764022827 0.04661702364683151 38.183986036635815 35.0 1.0 no 7831 chrXI_599909 22563 essential YKR086W 52 + CGTCAAAAGAACTAACGCCT S|19|* S|19|L 0 0 0 0 0.7370536669342064 P15938 0.17169180512428284 42.07221500440573 45.0 1.0 no 7832 chrXI_600033 22565 essential YKR086W 176 + AATCATTTTTAATGAACTTC I|60|M silent|ATC>ATT|I|60 0 0 0 0 0.6592799990972789 P15938 0.22095191478729248 32.514135911098315 20.0 1.0 no 7833 chrXI_600060r 22567 essential YKR086W 206 - CCTCTTCAGATTTATTCTTG E|75|Q E|75|K E|75|D silent|GAG>GAA|E|75 0 0 0 0 0.6070843636287985 P15938 0.4869956374168396 0.7490817308425903 0.5787022709846497 44.811612139864216 35.0 1.0 no 7834 chrXI_600109r 22568 essential YKR086W 255 - TTCTTTCTCTTATTTATAGA K|91|N silent|AAG>AAA|K|91 R|90|T R|90|K 0 0 0 0 0.02032985046551292 P15938 0.4819402098655701 0.5777400732040405 0.9656015038490297 38.240908302246744 20.0 1.0 no 7835 chrXI_600202r 22570 essential YKR086W 348 - CTCTTGAACAACGTCCGTGT K|122|N silent|AAG>AAA|K|122 0 0 0 0 0.8699822583879226 P15938 0.2584003210067749 49.05707533197432 50.0 1.0 no 7836 chrXI_600255 22571 essential YKR086W 398 + GCAGTATTCGCCCACCGTGA Q|134|E Q|134|* 0 0 0 0 -0.0063771259451691755 P15938 1.0 59.685985230299366 60.0 1.0 no 7837 chrXI_600233 22572 essential YKR086W 376 + AACTAAAGGCCAAACAGTTG L|127|V silent|CTA>TTA|L|127 0 0 0 0 0.7065625954149444 P15938 0.30727246403694153 39.703525787068145 40.0 1.0 no 7838 chrXI_600340r 22573 essential YKR086W 486 - TCAACTACTTCGCTTCGAGT E|169|Q E|169|K V|168|L V|168|I 0 0 0 0 -0.9269177790255524 P15938 0.5821393132209778 0.8194530010223389 0.7414964437484741 0.4381734728813171 48.16430358563763 45.0 1.0 no 7839 chrXI_600345 22575 essential YKR086W 488 + TCGAAGCGAAGTAGTTGAGG R|164|G R|164|* S|165|R silent|AGC>AGT|S|165 0 0 0 0 -0.3541298482160077 P15938 0.25763845443725586 0.28219303488731384 44.31051910812124 50.0 1.0 no 7840 chrXI_600417 22576 essential YKR086W 560 + ACCTCTGTCTGAATTGCCTG P|188|R P|188|L P|188|A P|188|S 0 0 0 0 0.1745463438952254 P15938 0.2234245985746384 0.1790122538805008 0.3226446807384491 0.3798172771930695 52.74073522500709 50.0 1.0 no 7841 chrXI_600418r 22577 essential YKR086W 564 - TCCTCAGGCAATTCAGACAG E|194|D silent|GAG>GAA|E|194 E|195|Q E|195|K 0 0 0 0 0.6412230617826771 P15938 0.4445253312587738 0.4106683135032654 0.5850914120674133 49.84334024364574 50.0 1.0 no 7842 chrXI_600511r 22579 essential YKR086W 657 - ATTCTTTGCTTGAGTGGTAT R|225|T R|225|K 0 0 0 0 1.0013516896853372 P15938 0.1544267237186432 0.2654523849487305 46.87255125146567 35.0 1.0 no 7843 chrXI_600624r 22580 essential YKR086W 770 - CCATTGATAAAGCGGATACT M|263|I M|263|I 0 0 0 0 -0.07049030316019114 P15938 0.463665634393692 0.463665634393692 42.683977380623155 40.0 1.0 no 7844 chrXI_600652r 22581 essential YKR086W 798 - TCACTGTCAGGATTCCTAAA S|272|T S|272|N E|273|Q E|273|K 0 0 0 0 -0.5075804278107047 P15938 0.025749029591679573 0.009915051981806757 0.16348184645175934 0.09025272727012634 45.58714862586334 40.0 1.0 no 7845 chrXI_600763 22582 essential YKR086W 906 + ACTGTTTTGAACACTGCCAT T|303|S T|303|I 0 0 0 0 0.3987573797464028 P15938 0.3801565170288086 0.061681818217039115 47.2485811104616 40.0 1.0 no 7846 chrXI_600762 22583 essential YKR086W 905 + CACTGTTTTGAACACTGCCA T|303|S T|303|I 0 0 0 0 0.7582302909307266 P15938 0.3801565170288086 0.061681818217039115 48.508053953410645 45.0 1.0 no 7847 chrXI_600952 22585 essential YKR086W 1095 + AATCAAGTAGTGGTGATAAT Q|367|E Q|367|* 0 0 0 0 -0.5008766433579428 P15938 0.044291440397500985 37.0690023294606 30.0 1.0 no 7848 chrXI_601006 22586 essential YKR086W 1149 + GCACAGTATTTATATGAAGA Q|385|E Q|385|* A|384|G A|384|V 0 0 0 0 -0.6881185656109899 P15938 0.0 0.09922410547733307 0.07078973203897476 38.25061176630851 30.0 1.0 no 7849 chrXI_601126r 22589 essential YKR086W 1272 - TAGCCTACTTCCTTACCCAA G|430|A G|430|D G|430|R G|430|S 0 0 0 0 -0.7191402095394961 P15938 0.0 0.0 0.0 0.0 53.90062892205232 45.0 1.0 no 7850 chrXI_601185 22590 essential YKR086W 1328 + TACAAAACTTAAGTTTGTAA T|444|R T|444|I 0 0 0 0 0.34238818433484697 P15938 0.0 0.0 30.819440123637552 20.0 1.0 no 7851 chrXI_601229r 22591 essential YKR086W 1375 - ATCGAGTGTATCATCCAATA D|465|H D|465|N 0 0 0 0 0.4687250021543053 P15938 0.002708990825340152 0.03761810809373856 43.54650716877109 35.0 1.0 no 7852 chrXI_601414 22593 essential YKR086W 1557 + GCTCCTCAGTTCACAATTCC P|521|A P|521|S A|520|G A|520|V 0 0 0 0 -0.22461028363906368 P15938 0.018279699608683583 0.05260595679283142 0.01088668406009674 1.0 54.55372742727127 50.0 1.0 no 7853 chrXI_602037 22602 essential YKR086W 2180 + CCTTTTACTGCTAAAATCTC L|728|V L|728|F 0 0 0 0 0.4190911420875292 P15938 1.0 0.005190901458263397 41.60192063988683 35.0 1.0 no 7854 chrXI_602120 22604 essential YKR086W 2263 + TATCCTCATTGTATGAGTTA S|756|C S|756|F silent|TCC>TCG|S|756 silent|TCC>TCT|S|756 0 0 0 0 0.10777513685908452 P15938 0.008935326710343361 0.004556738305836916 43.24412882624483 30.0 1.0 no 7855 chrXI_602123r 22605 essential YKR086W 2269 - GAACCATAACTCATACAATG W|762|C W|762|* W|762|S W|762|* 0 0 0 0 0.3106081296653243 P15938 0.0 0.0 37.347215170160155 35.0 1.0 no 7856 chrXI_602225r 22607 essential YKR086W 2371 - AACTGCAATTAATAAAATTT V|797|L V|797|I A|796|P A|796|T 0 0 0 0 -0.12773382718462564 P15938 0.3404693305492401 0.21270398795604706 0.024198833853006363 0.017783964052796364 29.141066341258348 15.0 1.0 no 7857 chrXII_39946 22609 essential YLL050C 309 - GATCTGACTGGAGCAGTGTC R|109|T R|109|K COF1 COFilin 143.0 0 1 0 0 -0.461213203146931 Q03048 0.932735025882721 0.955805003643036 0.009039459750056269 0.6995882987976074 1.912088394165039 0.1151380017399788 52.14005225441811 55.00000000000001 0.0 no 7858 chrXII_39972r 22610 essential YLL050C 280 + CCAAGATTGTTTTCTTCACT silent|TCC>TCG|S|94 silent|TCC>TCT|S|94 COF1 COFilin 143.0 0 0 0 0 0.19835601609532427 Q03048 45.33118085224515 35.0 0.0 no 7859 chrXII_39972 22611 essential YLL050C 283 - CCAAGTGAAGAAAACAATCT W|101|S W|101|* COF1 COFilin 143.0 0 1 0 0 -3.2243277178807124 Q03048 35.97322795070943 35.0 0.0 yes 7860 chrXII_40020 22612 essential YLL050C 235 - TTCGTATTCAAAATCGTAAA E|85|Q E|85|K COF1 COFilin 143.0 0 0 0 0 -0.2818189523808952 Q03048 34.039320404073464 25.0 0.0 no 7861 chrXII_40059 22614 essential YLL050C 196 - TTCTGGCAATTTCTCTAAGA E|72|Q E|72|K L|70|F silent|TTG>TTA|L|70 COF1 COFilin 143.0 0 0 0 0 -0.4418689424688816 Q03048 0.956179976463318 0.9475290179252625 0.2025049775838852 0.22847536206245425 0.42875200510025024 0.03530599921941757 43.4126722695745 35.0 0.0 no 7862 chrXII_40172r 22618 essential YLL050C 80 + CGCTTTCAATGACTTGAAAT A|28|G A|28|V F|29|L silent|TTC>TTT|F|29 COF1 COFilin 143.0 0 1 0 0 0.18505404790312124 Q03048 39.572035757746505 35.0 0.0 no 7863 chrXII_64989 22622 essential YLR167W 199 - TAGCCTTAGCACAAGATGTA error error error error RPS31 Ribosomal Protein of the Small subunit 152.0 0 0 0 0 0.6538137863041874 P05759 46.28038585669025 40.0 1.0 no 7864 chrXII_64992r 22624 essential YLR167W 193 + CCACCTTACATCTTGTGCTA error error error error RPS31 Ribosomal Protein of the Small subunit 152.0 0 0 0 0 -0.20906839519994347 P05759 52.51596688462479 45.0 1.0 no 7865 chrXII_65018r 22625 essential YLR167W 167 + GTCTGATTACAACATTCAGA error error RPS31 Ribosomal Protein of the Small subunit 152.0 0 0 0 0 0.5149319538377641 P05759 41.190470996463375 35.0 1.0 no 7866 chrXII_65078 22626 essential YLR167W 110 - TCAATCTTTGTTGATCTGGA error error error error RPS31 Ribosomal Protein of the Small subunit 152.0 0 0 0 0 0.3186984015095883 P05759 43.66439473434826 35.0 1.0 no 7867 chrXII_67151 22628 essential YLL036C 1086 - AATCTAGAGCTTGCCTGGTC R|368|T R|368|K PRP19 Pre-RNA Processing 503.0 0 0 0 0 -0.5565448225751961 P32523 0.9788659811019896 0.9986129999160768 0.3678679764270783 0.19724935293197632 0.40474000573158253 0.7964199781417847 52.68016568138819 50.0 0.0 no 7868 chrXII_67164r 22629 essential YLL036C 1070 + CAACTTGTCATCACCTGACC N|358|K silent|AAC>AAT|N|358 PRP19 Pre-RNA Processing 503.0 0 0 0 0 0.24326478006319546 P32523 0.9845200181007384 0.029222585260868076 0.12933999300003052 50.149558904393864 50.0 0.0 no 7869 chrXII_67291 22633 essential YLL036C 946 - ATACTGGGAATCATCCTCGT Q|321|H silent|CAG>CAA|Q|321 PRP19 Pre-RNA Processing 503.0 0 0 0 0 0.1630150388246889 P32523 1.0006899833679201 0.04210038110613823 -0.7064200043678284 49.015530741400035 45.0 0.0 no 7870 chrXII_67306 22635 essential YLL036C 931 - CTCGTAGGATTGAAATCCTA E|317|Q E|317|K PRP19 Pre-RNA Processing 503.0 0 0 0 0 0.094481355376733 P32523 1.0004899501800537 0.9891330003738404 0.2655310034751892 0.3840969204902649 0.029659999534487724 0.13944000005722046 43.45098602764125 40.0 0.0 no 7871 chrXII_67331r 22637 essential YLL036C 903 + TTCATCTGGGCGGATAATAG F|302|L silent|TTC>TTT|F|302 I|303|M silent|ATC>ATT|I|303 PRP19 Pre-RNA Processing 503.0 0 0 0 0 0.2293696580054945 P32523 0.9824680089950562 1.0027899742126465 0.6220813393592834 0.040815219283103936 1.7984800338745115 0.38967999815940857 45.274275417011786 45.0 0.0 no 7872 chrXII_67344r 22639 essential YLL036C 890 + CAACACAGAGTACTTCATCT N|298|K silent|AAC>AAT|N|298 T|299|R T|299|I PRP19 Pre-RNA Processing 503.0 0 0 0 0 0.007431583412800784 P32523 0.9845200181007384 0.9773380160331726 0.9893620014190674 0.2457498013973236 0.28021135926246643 0.11094114184379578 -0.5684999823570251 -0.01616000011563301 43.425846599031104 40.0 0.0 no 7873 chrXII_67345r 22640 essential YLL036C 889 + TCAACACAGAGTACTTCATC silent|GTC>GTG|V|297 silent|GTC>GTT|V|297 N|298|K silent|AAC>AAT|N|298 PRP19 Pre-RNA Processing 503.0 0 0 0 0 0.8911534903993181 P32523 0.9845200181007384 0.2457498013973236 42.52754841504577 40.0 0.0 no 7874 chrXII_67381 22641 essential YLL036C 856 - ATACATATATATAATCTCAT M|291|I M|291|I PRP19 Pre-RNA Processing 503.0 0 0 0 0 0.7741256133897907 P32523 0.999705970287323 0.999705970287323 0.7574827075004578 0.7574827075004578 0.7040799856185913 0.7040799856185913 31.792262558082147 15.0 0.0 no 7875 chrXII_67407 22642 essential YLL036C 830 - AATCTACCTCTATTTCTCTG D|283|H D|283|N V|282|L V|282|I PRP19 Pre-RNA Processing 503.0 0 0 0 0 0.11457393189098393 P32523 0.9897220134735109 1.0002599954605105 0.9940739870071412 1.0010499954223633 0.1217213049530983 0.4860699474811554 0.7732540965080261 0.5222316980361938 0.0824199989438057 -0.09510000050067903 -0.04053999856114388 -0.5458599925041199 44.42146570595417 35.0 0.0 no 7876 chrXII_67502r 22643 essential YLL036C 732 + CATCCAGCTATTATTTCCAG P|246|A P|246|S P|246|R P|246|L PRP19 Pre-RNA Processing 503.0 0 0 0 0 -0.7397197636579316 P32523 1.0004199743270874 0.9926369786262512 0.9753050208091736 0.9834169745445251 0.4852445423603058 0.399023562669754 0.31710487604141235 0.20743235945701602 3.0349600315093994 3.683759927749634 12.768959999084473 7.139619827270508 48.132948774890615 40.0 0.0 no 7877 chrXII_67529r 22644 essential YLL036C 705 + ACACCAAATCCCCGTACCGG P|237|A P|237|S T|236|R T|236|I PRP19 Pre-RNA Processing 503.0 0 0 0 0 -0.5425977901522155 P32523 1.0004199743270874 0.9926369786262512 0.9773380160331726 0.9893620014190674 0.5568629503250122 0.5676876902580261 0.5382894277572632 0.22819983959198 1.8446600437164309 1.95524001121521 2.4159998893737797 -1.799299955368042 55.16868459103824 60.0 0.0 no 7878 chrXII_67531r 22646 essential YLL036C 703 + CTACACCAAATCCCCGTACC T|236|R T|236|I P|237|A P|237|S PRP19 Pre-RNA Processing 503.0 0 0 0 0 -0.2380623475655161 P32523 0.9773380160331726 0.9893620014190674 1.0004199743270874 0.9926369786262512 0.5382894277572632 0.22819983959198 0.5568629503250122 0.5676876902580261 2.4159998893737797 -1.799299955368042 1.8446600437164309 1.95524001121521 53.53238574659025 55.00000000000001 0.0 no 7879 chrXII_67530r 22647 essential YLL036C 704 + TACACCAAATCCCCGTACCG T|236|R T|236|I P|237|A P|237|S PRP19 Pre-RNA Processing 503.0 0 0 0 0 0.2668090800471343 P32523 0.9773380160331726 0.9893620014190674 1.0004199743270874 0.9926369786262512 0.5382894277572632 0.22819983959198 0.5568629503250122 0.5676876902580261 2.4159998893737797 -1.799299955368042 1.8446600437164309 1.95524001121521 52.6901842040902 55.00000000000001 0.0 no 7880 chrXII_67532r 22648 essential YLL036C 702 + ACTACACCAAATCCCCGTAC T|235|S T|235|I T|236|R T|236|I PRP19 Pre-RNA Processing 503.0 0 0 0 0 0.15097839739505847 P32523 0.9913139939308168 0.9893620014190674 0.9773380160331726 0.9893620014190674 0.33173227310180664 0.7026087641716003 0.5382894277572632 0.22819983959198 0.6752399802207947 -0.06171999871730805 2.4159998893737797 -1.799299955368042 50.670215134635384 50.0 0.0 no 7881 chrXII_67630r 22650 essential YLL036C 604 + AATCTATGTACTATGATAAA S|203|C S|203|F PRP19 Pre-RNA Processing 503.0 0 0 0 0 -0.2338695186018885 P32523 0.9879119992256165 0.9685909748077391 0.019356770440936092 0.02065325900912285 0.10881999880075456 -0.4680399894714356 31.713808683394063 20.0 0.0 no 7882 chrXII_67629r 22651 essential YLL036C 605 + ATCTATGTACTATGATAAAT S|203|C S|203|F PRP19 Pre-RNA Processing 503.0 0 0 0 0 0.34766230215054955 P32523 0.9879119992256165 0.9685909748077391 0.019356770440936092 0.02065325900912285 0.10881999880075456 -0.4680399894714356 32.89843257894137 20.0 0.0 no 7883 chrXII_67735r 22652 essential YLL036C 499 + GCAAGCTCAAAGCACCCAAA silent|GGC>GGG|G|167 silent|GGC>GGT|G|167 L|169|V L|169|F PRP19 Pre-RNA Processing 503.0 0 0 0 0 -1.0687468909828874 P32523 0.9950990080833436 1.0031700134277344 0.5568538904190063 0.13982175290584564 48.4201235850025 50.0 0.0 no 7884 chrXII_67757r 22653 essential YLL036C 477 + TCTAGAGACTTTGTAGCGAG S|160|C S|160|F PRP19 Pre-RNA Processing 503.0 0 0 0 0 -0.3091331272830587 P32523 0.9879119992256165 0.9685909748077391 0.05390061810612679 0.094431534409523 45.00994066994769 45.0 0.0 no 7885 chrXII_67758r 22654 essential YLL036C 476 + TTCTAGAGACTTTGTAGCGA S|160|C S|160|F PRP19 Pre-RNA Processing 503.0 0 0 0 0 0.4755914930344245 P32523 0.9879119992256165 0.9685909748077391 0.05390061810612679 0.094431534409523 45.21596861291584 40.0 0.0 no 7886 chrXII_67793r 22656 essential YLL036C 441 + ACGAGAGAAGAATTTTTACA T|148|R T|148|M PRP19 Pre-RNA Processing 503.0 0 0 0 0 0.8860237253778953 P32523 0.9773380160331726 0.9916599988937378 0.5152560472488403 0.10741528123617172 35.640777171714255 30.0 0.0 no 7887 chrXII_67823 22657 essential YLL036C 414 - ACCGCTTGCTGTGAGGATTT silent|GCG>GCC|A|144 silent|GCG>GCA|A|144 V|145|L V|145|I PRP19 Pre-RNA Processing 503.0 0 0 0 1 -1.5043984577420826 P32523 0.9940739870071412 1.0010499954223633 0.5647474527359009 0.99125874042511 53.79640281061604 50.0 0.0 no 7888 chrXII_68105 22660 essential YLL036C 132 - ACTATTTCTTCGATGCTTAA V|51|L V|51|M PRP19 Pre-RNA Processing 503.0 0 0 0 0 0.602711954744404 P32523 0.924390971660614 0.9335200190544128 0.07196033000946045 0.01349882036447525 -0.6007599830627441 -0.7330399751663208 -0.5254200100898743 -0.8619099855422974 -0.7331100106239319 -1.1391199827194214 41.60763674792315 30.0 0.0 no 7889 chrXII_68104 22661 essential YLL036C 133 - CACTATTTCTTCGATGCTTA V|51|L V|51|M PRP19 Pre-RNA Processing 503.0 0 0 0 0 0.7632352752495705 P32523 0.924390971660614 0.9335200190544128 0.07196033000946045 0.01349882036447525 -0.6007599830627441 -0.7330399751663208 -0.5254200100898743 -0.8619099855422974 -0.7331100106239319 -1.1391199827194214 44.42401798219793 35.0 0.0 no 7890 chrXII_68149r 22662 essential YLL036C 85 + AACAGTATGTTAAAGATACG Q|30|E Q|30|* PRP19 Pre-RNA Processing 503.0 0 1 0 0 0.05727626518687864 P32523 0.934469997882843 0.8292446732521057 0.4789679944515228 33.757922813981395 30.0 0.0 no 7891 chrXII_68154 22664 essential YLL036C 83 - TATCTTTAACATACTGTTCA D|34|H D|34|N PRP19 Pre-RNA Processing 503.0 0 1 0 0 -0.21069507850106234 P32523 0.9202659726142884 0.9315000176429749 0.054600406438112266 0.1676027625799179 -0.3577040135860443 -0.14696000516414642 38.269246855387394 25.0 0.0 no 7892 chrXII_68179 22665 essential YLL036C 58 - CGACTTTTCAAAAATAGTCC K|25|N silent|AAG>AAA|K|25 PRP19 Pre-RNA Processing 503.0 0 1 0 0 0.97163575040672 P32523 0.912319004535675 0.0 1.3547940254211426 38.33166573446265 35.0 0.0 no 7893 chrXII_68186 22666 essential YLL036C 51 - TCAAAAATAGTCCTGGATTT E|24|Q E|24|K PRP19 Pre-RNA Processing 503.0 0 1 0 0 0.3517628241572535 P32523 1.0002599954605105 0.9889079928398132 0.0 0.0 2.167011976242065 2.791843891143799 38.554969130703505 30.0 0.0 no 7894 chrXII_68607 22667 essential YLL035W 27 + CCTCAATATACCAAAGATTC Q|11|E Q|11|* P|10|R P|10|L GRC3 632.0 0 0 0 0 -0.06749674418016871 Q07845 0.9590039849281312 0.9432820081710817 0.9430609941482544 39.954562622483024 35.0 1.0 no 7895 chrXII_68737 22669 essential YLL035W 157 + ACGAAGGTGATGACTTGAAC D|53|E silent|GAC>GAT|D|53 GRC3 632.0 0 0 0 0 0.941607016017474 Q07845 0.9532920122146606 0.8257573246955872 40.86320990631293 45.0 1.0 no 7896 chrXII_68775 22670 essential YLL035W 195 + ATCGATAATATAACGTATGA I|66|M silent|ATC>ATT|I|66 GRC3 632.0 0 0 0 0 0.7270940219277028 Q07845 0.9598389863967896 0.06257713586091995 33.8524435058074 25.0 1.0 no 7897 chrXII_68835 22671 essential YLL035W 255 + AAACAGAAGTTACATTTATC Q|87|E Q|87|* GRC3 632.0 0 0 0 0 -0.01463404879230737 Q07845 0.9590039849281312 0.0 32.906680430748786 25.0 1.0 no 7898 chrXII_69159r 22674 essential YLL035W 582 - CTCTCGTTTAATGGAAAGTA E|200|D silent|GAG>GAA|E|200 E|200|Q E|200|K GRC3 632.0 0 0 0 0 -0.6465781421367462 Q07845 0.94931298494339 0.956179976463318 0.9475290179252625 0.6922382712364197 0.4962057173252106 1.0 39.74239298839848 35.0 1.0 no 7899 chrXII_69216 22675 essential YLL035W 636 + ATTCAATCTTTATCCGTGCC Q|214|E Q|214|* GRC3 632.0 0 0 0 0 -0.2800464848255223 Q07845 0.9590039849281312 1.0 49.02201354040506 40.0 1.0 no 7900 chrXII_69234r 22676 essential YLL035W 657 - AACGGAGTTGACCAATATCC silent|CCG>CCC|P|225 silent|CCG>CCA|P|225 GRC3 632.0 0 0 0 0 1.0421340777847121 Q07845 45.32674398236327 45.0 1.0 no 7901 chrXII_69252r 22677 essential YLL035W 675 - CTCAAATATAACTTCTCTAA L|231|F silent|TTG>TTA|L|231 GRC3 632.0 0 0 0 0 0.3065699970634995 Q07845 0.9587849974632264 0.14846201241016388 34.162530050610535 25.0 1.0 no 7902 chrXII_69297 22679 essential YLL035W 717 + ACAAGAATCATGGTGATTGG T|240|R T|240|I GRC3 632.0 0 0 0 0 -2.408110347979294 Q07845 0.9476869702339172 0.9472420215606691 0.1599372774362564 0.6334667205810547 40.37728428124075 40.0 1.0 yes 7903 chrXII_69467r 22682 essential YLL035W 890 - GGCTGGAAAGAATCTTATTC S|303|T S|303|N GRC3 632.0 0 0 0 0 -0.4511003395523906 Q07845 0.9512869715690612 0.9536849856376648 0.6144613027572632 0.5792213678359985 41.18287916490243 40.0 1.0 no 7904 chrXII_69498 22684 essential YLL035W 918 + CTCGGACAACATCTCTGCCA silent|CTC>CTG|L|307 silent|CTC>CTT|L|307 Q|309|E Q|309|* GRC3 632.0 0 0 0 0 0.4028482641232085 Q07845 0.9590039849281312 0.3469284474849701 52.93408004193861 55.00000000000001 1.0 no 7905 chrXII_69551 22687 essential YLL035W 971 + CGCTGGCTCCTCTTCCCCGC A|325|G A|325|V silent|GGC>GGG|G|326 silent|GGC>GGT|G|326 GRC3 632.0 0 0 0 0 0.5304039630696235 Q07845 0.9484469890594482 0.9504740238189696 0.052822072058916085 0.8104767799377441 69.38131084080442 75.0 1.0 no 7906 chrXII_69646 22690 essential YLL035W 1066 + CGTCATTGCTTAATCTACCT S|357|* S|357|L GRC3 632.0 0 0 0 0 -0.8880162664462659 Q07845 0.9298099875450134 0.0 47.4887780294959 40.0 1.0 no 7907 chrXII_69657 22691 essential YLL035W 1077 + AATCTACCTGGGTGGATAAA L|361|V silent|CTA>TTA|L|361 P|362|A P|362|S GRC3 632.0 0 0 0 0 1.1960979348441918 Q07845 0.9512209892272948 0.9562489986419678 0.9498909711837769 0.04624326154589653 0.0 0.0 43.43297100992942 40.0 1.0 no 7908 chrXII_69663r 22694 essential YLL035W 1086 - CCGAATCCTTTTATCCACCC G|369|R G|369|R G|367|A G|367|E GRC3 632.0 0 0 0 0 -1.925586061845181 Q07845 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.0 0.0 0.0 0.0 54.09423493772556 50.0 1.0 no 7909 chrXII_69749 22696 essential YLL035W 1169 + AGCTAATTCGAAAAGACACC A|391|G A|391|V GRC3 632.0 0 0 0 0 -0.6911539389967993 Q07845 0.9484469890594482 0.9504740238189696 0.2913446724414825 0.1917070746421814 39.66793147323932 40.0 1.0 no 7910 chrXII_69978 22699 essential YLL035W 1398 + TTGCAAATTTCATATGGCAA Q|468|E Q|468|* GRC3 632.0 0 0 0 0 -0.2801695204521932 Q07845 0.9590039849281312 0.12515157461166382 39.776246972114734 30.0 1.0 no 7911 chrXII_69975r 22700 essential YLL035W 1398 - TTGCCATATGAAATTTGCAA G|472|A G|472|D G|472|R G|472|S GRC3 632.0 0 0 0 0 1.0814458677378376 Q07845 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 40.2371645193989 30.0 1.0 no 7912 chrXII_71277r 22702 essential YLL034C 1847 + ACAAGTTTTTACTAGAGCAA Q|617|E Q|617|* RIX7 RIbosome eXport 837.0 0 0 0 0 -0.13919569047902525 Q07844 0.013664891943335531 38.961683994014955 30.0 0.0 no 7913 chrXII_71324 22703 essential YLL034C 1803 - ACGTATTTATTTAATAATTC V|608|L V|608|I RIX7 RIbosome eXport 837.0 0 0 0 0 1.1704046632688945 Q07844 0.08230608701705933 0.03139512613415718 -1.0820000171661377 -0.8248000144958496 30.91419820799979 15.0 0.0 no 7914 chrXII_71402 22704 essential YLL034C 1725 - AACGTTTTACCACAACCTGG silent|ACG>ACC|T|581 silent|ACG>ACA|T|581 RIX7 RIbosome eXport 837.0 0 0 0 0 -0.0640645860840606 Q07844 46.299206804673354 45.0 0.0 no 7915 chrXII_71428 22706 essential YLL034C 1699 - CCACAATAAAACACCACCAG L|572|F silent|TTG>TTA|L|572 W|573|S W|573|* RIX7 RIbosome eXport 837.0 0 0 0 0 0.44659800666708976 Q07844 0.011327225714921951 0.0127683375030756 2.9384000301361084 42.830795797057476 45.0 0.0 no 7916 chrXII_71459 22707 essential YLL034C 1668 - CCCACTTTTTCATAAAGCTC silent|GTG>GTC|V|562 silent|GTG>GTA|V|562 G|563|R G|563|R RIX7 RIbosome eXport 837.0 0 0 0 0 -0.2998302293948917 Q07844 0.0 0.0 5.005799770355225 5.005799770355225 46.69373434803356 40.0 0.0 no 7917 chrXII_71460r 22708 essential YLL034C 1664 + ACCAGAGCTTTATGAAAAAG P|556|R P|556|L P|556|A P|556|S RIX7 RIbosome eXport 837.0 0 0 0 0 0.19281093924296647 Q07844 0.052707232534885406 0.0069061280228197575 0.0192584190517664 0.012432112358510494 37.37368594213842 35.0 0.0 no 7918 chrXII_71543 22709 essential YLL034C 1584 - ACATTAGCCCAAGTAACATC V|535|L V|535|I RIX7 RIbosome eXport 837.0 0 0 0 0 0.3254134841745531 Q07844 0.1071419045329094 1.0 0.1316000074148178 -1.186400055885315 45.11566519163557 40.0 0.0 no 7919 chrXII_71550r 22710 essential YLL034C 1574 + TACGGTACCTGATGTTACTT T|526|R T|526|M RIX7 RIbosome eXport 837.0 0 0 0 0 -0.15761585860792834 Q07844 0.0 0.0 46.768959202081696 40.0 0.0 no 7920 chrXII_71686 22712 essential YLL034C 1441 - ACGAATAAATTGTTGGACTA R|487|P R|487|H RIX7 RIbosome eXport 837.0 0 0 0 0 -0.4770192840300234 Q07844 0.2646546959877014 0.11816782504320145 1.9170000553131104 1.228600025177002 36.1183290948494 30.0 0.0 no 7921 chrXII_71727 22713 essential YLL034C 1400 - TCATATTCGCAGTGTTCTTC M|473|I M|473|I RIX7 RIbosome eXport 837.0 0 0 0 0 0.6856038440551308 Q07844 0.19608232378959656 0.19608232378959656 0.8343999981880188 0.8343999981880188 48.10696714039307 40.0 0.0 no 7922 chrXII_71954r 22718 essential YLL034C 1170 + TCTGATAACCTAAAAATTGA S|391|C S|391|F RIX7 RIbosome eXport 837.0 0 0 0 0 1.3796448970546151 Q07844 0.2642251551151276 0.020719045773148537 33.448790526142034 25.0 0.0 no 7923 chrXII_71931r 22719 essential YLL034C 1193 + TGCTATCGATTTTGCCAAAT A|399|G A|399|V I|400|M silent|ATC>ATT|I|400 RIX7 RIbosome eXport 837.0 0 0 0 0 0.9061748745203856 Q07844 0.2320558875799179 0.0549498088657856 0.05229545384645462 0.5992000102996826 0.7149999737739563 -1.784000039100647 44.125167758819195 35.0 0.0 no 7924 chrXII_72069r 22720 essential YLL034C 1055 + CACGAATAGACCTGACTCTT T|353|R T|353|M RIX7 RIbosome eXport 837.0 0 0 0 0 -0.7602792062715062 Q07844 0.002348397392779589 0.0013346984051167965 45.223700097473966 45.0 0.0 no 7925 chrXII_72003 22721 essential YLL034C 1124 - AGACTTCATTCGGGACATTC V|381|L V|381|I E|380|Q E|380|K RIX7 RIbosome eXport 837.0 0 0 0 0 0.7082235660559956 Q07844 0.2909683585166931 0.1803564727306366 0.059970084577798836 0.01408357825130224 -0.7671999931335449 -0.5867999792098999 46.84699848703275 45.0 0.0 no 7926 chrXII_72141 22722 essential YLL034C 986 - CATCCATTGAGGTCAATAAT D|335|H D|335|N M|334|I M|334|I RIX7 RIbosome eXport 837.0 0 0 0 0 -1.7658150940640671 Q07844 0.0026805507950484753 0.009159173816442491 0.21677373349666595 0.21677373349666595 41.88161805286995 35.0 0.0 no 7927 chrXII_72171 22723 essential YLL034C 956 - TTCTTCTCTCCATTTCTCTT R|325|T R|325|K R|324|T R|324|K RIX7 RIbosome eXport 837.0 0 0 0 0 -0.34466111487238404 Q07844 0.0 0.0 0.12072240561246872 0.6835025548934937 51.427416974770956 35.0 0.0 no 7928 chrXII_72199 22724 essential YLL034C 928 - TCCATCACGTTTTGGTGTAA G|316|R G|316|R G|316|A G|316|E RIX7 RIbosome eXport 837.0 0 0 0 0 0.14997551723330216 Q07844 0.057375527918338776 0.057375527918338776 0.3452323079109192 0.07997798174619675 -0.121799997985363 -0.121799997985363 0.358599990606308 0.08980000019073486 48.01492660724148 40.0 0.0 no 7929 chrXII_72200r 22725 essential YLL034C 924 + GCCATTACACCAAAACGTGA silent|GCC>GCG|A|309 silent|GCC>GCT|A|309 A|309|G A|309|V RIX7 RIbosome eXport 837.0 0 0 0 0 -0.2776296168234321 Q07844 0.025030838325619698 0.11618943512439728 1.1690000295639038 -0.06840000301599503 45.775690140906995 45.0 0.0 no 7930 chrXII_72305r 22727 essential YLL034C 819 + TCAGTCGTAAGTGGTATGTC S|274|* S|274|L silent|GTC>GTG|V|275 silent|GTC>GTT|V|275 RIX7 RIbosome eXport 837.0 0 0 0 0 -1.210165608879811 Q07844 0.027188384905457497 47.49892109810651 45.0 0.0 no 7931 chrXII_72308 22728 essential YLL034C 819 - GACATACCACTTACGACTGA M|279|I M|279|I G|278|A G|278|D RIX7 RIbosome eXport 837.0 0 0 0 0 0.6237900587711019 Q07844 0.027859549969434738 0.027859549969434738 0.0 0.0 0.27399998903274536 0.27399998903274536 45.51836107522274 45.0 0.0 no 7932 chrXII_72314r 22729 essential YLL034C 810 + TCTGCACCTTCAGTCGTAAG S|271|C S|271|F A|272|G A|272|V RIX7 RIbosome eXport 837.0 0 0 0 0 -4.28632003309362 Q07844 0.00416420539841056 0.0016774064861238005 0.018784914165735245 0.005881345830857754 -1.1613999605178833 6.88539981842041 51.14940693548016 50.0 0.0 yes 7933 chrXII_72383 22731 essential YLL034C 744 - ATCGACGTCTTACCGCAACC silent|TCG>TCC|S|254 silent|TCG>TCA|S|254 silent|ACG>ACC|T|253 silent|ACG>ACA|T|253 RIX7 RIbosome eXport 837.0 0 0 0 0 -0.6246704866663874 Q07844 51.78124884902986 55.00000000000001 0.0 no 7934 chrXII_72410 22736 essential YLL034C 717 - CCATGCAACAGAACACCTCT G|246|R G|246|S L|244|F silent|TTG>TTA|L|244 RIX7 RIbosome eXport 837.0 0 0 0 0 -1.9607984788587505 Q07844 0.0 0.0 0.009977883659303188 0.7436000108718872 49.622782486667965 50.0 0.0 no 7935 chrXII_72413 22738 essential YLL034C 714 - TGCAACAGAACACCTCTAGG L|244|F silent|TTG>TTA|L|244 silent|CTG>CTC|L|243 silent|CTG>CTA|L|243 RIX7 RIbosome eXport 837.0 0 0 0 0 -0.26498615234112066 Q07844 0.009977883659303188 0.7436000108718872 46.672964513200334 50.0 0.0 no 7936 chrXII_72443r 22741 essential YLL034C 681 + CCAGAGATATTTTTATCCAC P|228|R P|228|L RIX7 RIbosome eXport 837.0 0 0 0 0 -0.7640997090643759 Q07844 0.0 0.0 43.43495403755424 35.0 0.0 no 7937 chrXII_72444r 22742 essential YLL034C 680 + TCCAGAGATATTTTTATCCA P|228|R P|228|L P|228|A P|228|S RIX7 RIbosome eXport 837.0 0 0 0 0 -0.057044396858034786 Q07844 0.0 0.0 0.0 0.0 43.964154554495046 30.0 0.0 no 7938 chrXII_72508 22744 essential YLL034C 619 - GACATCATCCATACCACCTA V|213|L V|213|I D|212|H D|212|N RIX7 RIbosome eXport 837.0 0 0 0 0 0.018688913795656514 Q07844 0.10526561737060547 0.39937081933021545 0.14090757071971893 0.521781325340271 0.9520000219345092 -0.4503999948501587 51.00208385447309 45.0 0.0 no 7939 chrXII_72516r 22745 essential YLL034C 608 + TCTGAAATCCTTAGGTGGTA L|204|V silent|CTG>TTG|L|204 RIX7 RIbosome eXport 837.0 0 0 0 0 -0.3391098455032745 Q07844 0.035788744688034065 2.333400011062622 45.91471990704849 40.0 0.0 no 7940 chrXII_72521r 22746 essential YLL034C 603 + TCGTCTCTGAAATCCTTAGG S|202|W S|202|L S|203|C S|203|F RIX7 RIbosome eXport 837.0 0 0 0 0 0.3336758143689551 Q07844 0.019983641803264614 0.4162974059581757 0.04245448112487793 0.03644295409321785 0.03759999945759773 -0.8554000258445741 46.53365956803497 45.0 0.0 no 7941 chrXII_72646 22747 essential YLL034C 481 - ATCAGTTTCTGTTATAGACT D|167|H D|167|N RIX7 RIbosome eXport 837.0 0 1 0 0 0.5450670168873166 Q07844 0.12005391716957092 0.4999186396598816 -0.1826000064611435 -0.13819999992847445 42.41786943796785 30.0 0.0 no 7942 chrXII_72688r 22750 essential YLL034C 436 + ACAAACGCATAACTAGCACG N|146|K silent|AAC>AAT|N|146 R|148|G R|148|C RIX7 RIbosome eXport 837.0 0 0 0 0 -0.10567570833405074 Q07844 0.009810631163418293 0.09108731895685196 0.012800461612641813 41.392628404814566 45.0 0.0 no 7943 chrXII_72783 22752 essential YLL034C 344 - CCTCTTCGTTGTTGTAACCT E|121|Q E|121|K E|121|D silent|GAG>GAA|E|121 RIX7 RIbosome eXport 837.0 0 0 0 0 -0.8017768422154476 Q07844 0.4920530915260315 0.7358777523040771 0.5039554238319397 52.33175930528347 45.0 0.0 no 7944 chrXII_73000 22754 essential YLL034C 127 - GTTCTCGCCCTCTTCTCCTT E|48|D silent|GAG>GAA|E|48 E|48|Q E|48|K RIX7 RIbosome eXport 837.0 0 0 0 0 -0.1304611026173942 Q07844 63.89985982812499 55.00000000000001 0.0 no 7945 chrXII_78015 22757 essential YLL031C 2171 - TCAAACCAAGGATACCCTTT L|730|F silent|TTG>TTA|L|730 G|729|A G|729|D GPI13 GlycosylPhosphatidylInositol anchor biosynthesis 1017.0 0 0 0 0 0.033022359912052435 Q07830 0.9587849974632264 0.9499930143356324 0.9446240067481996 0.7331870198249817 0.1469392031431198 0.048110149800777435 46.00387898799318 40.0 0.0 no 7946 chrXII_78049r 22758 essential YLL031C 2134 + ATCAAGCTGCAGCTCCAATT Q|713|E Q|713|* A|714|G A|714|V GPI13 GlycosylPhosphatidylInositol anchor biosynthesis 1017.0 0 0 0 0 0.041911501047154257 Q07830 0.9590039849281312 0.9484469890594482 0.9504740238189696 0.0634952113032341 1.0 0.04188764095306397 50.859558120563115 45.0 0.0 no 7947 chrXII_78148r 22759 essential YLL031C 2035 + ATCAAAACAATTCCTCGTGG Q|680|E Q|680|* GPI13 GlycosylPhosphatidylInositol anchor biosynthesis 1017.0 0 1 0 0 1.1497023908304742 Q07830 0.9590039849281312 0.5327848196029663 41.526437646120094 40.0 0.0 no 7948 chrXII_78196 22760 essential YLL031C 1990 - GCCTTGTTCCTCTCTACAAA G|670|R G|670|S G|670|A G|670|D GPI13 GlycosylPhosphatidylInositol anchor biosynthesis 1017.0 0 0 0 0 0.3883198477049694 Q07830 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.2253918051719665 0.3516625761985779 0.5138914585113525 0.48196026682853704 52.05507816886899 45.0 0.0 no 7949 chrXII_78367 22763 essential YLL031C 1819 - TGCAGTTAATAATGCAGTGG A|613|P A|613|T GPI13 GlycosylPhosphatidylInositol anchor biosynthesis 1017.0 0 1 0 0 0.8583881339163228 Q07830 0.9573720097541808 0.9523990154266356 42.80285469811958 40.0 0.0 no 7950 chrXII_78434r 22765 essential YLL031C 1749 + GCATTCCTTTTATCTACTTT A|584|G A|584|V F|585|L silent|TTC>TTT|F|585 GPI13 GlycosylPhosphatidylInositol anchor biosynthesis 1017.0 0 0 0 0 1.2158862718259154 Q07830 0.9484469890594482 0.9504740238189696 0.9387490153312684 0.3835188150405884 0.06937317550182343 0.03899354487657547 46.449479615615985 30.0 0.0 no 7951 chrXII_78472r 22767 essential YLL031C 1711 + CTTCCAATTCATTTACTATT S|572|C S|572|F silent|TCC>TCG|S|572 silent|TCC>TCT|S|572 GPI13 GlycosylPhosphatidylInositol anchor biosynthesis 1017.0 0 0 0 0 0.06235378590984264 Q07830 0.945252001285553 0.9294660091400146 0.0 0.0 40.41476882590092 25.0 0.0 no 7952 chrXII_78631 22768 essential YLL031C 1555 - ACCAATTGCAGTCGCTAACA G|525|R G|525|S G|525|A G|525|D GPI13 GlycosylPhosphatidylInositol anchor biosynthesis 1017.0 0 0 0 0 -2.298432772409859 Q07830 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 48.255931737850396 45.0 0.0 yes 7953 chrXII_78819r 22770 essential YLL031C 1364 + AACGCTACTGGCCACTTCAC T|456|R T|456|M L|457|V silent|CTA>TTA|L|457 GPI13 GlycosylPhosphatidylInositol anchor biosynthesis 1017.0 0 0 0 0 -0.5167538128027709 Q07830 0.9476869702339172 0.9502379894256592 0.9512209892272948 0.3888889849185944 0.18464337289333346 0.2585040628910065 52.66450507355501 55.00000000000001 0.0 no 7954 chrXII_78835 22771 essential YLL031C 1351 - TAGCGTTATACCGGTGGCAA silent|ACG>ACC|T|456 silent|ACG>ACA|T|456 GPI13 GlycosylPhosphatidylInositol anchor biosynthesis 1017.0 0 0 0 0 0.4609650889215154 Q07830 51.16651526292492 50.0 0.0 no 7955 chrXII_78924r 22775 essential YLL031C 1259 + TCCAGAAAAATTTGTTAAGC P|421|R P|421|L P|421|A P|421|S GPI13 GlycosylPhosphatidylInositol anchor biosynthesis 1017.0 0 0 0 0 -0.07566596198434805 Q07830 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.3468191623687744 0.6480473875999451 0.5059317350387573 0.4000329077243805 36.12759731263998 30.0 0.0 no 7956 chrXII_78990r 22778 essential YLL031C 1193 + CCATGGCAATGACGAAATAT H|399|D H|399|Y silent|GGC>GGG|G|400 silent|GGC>GGT|G|400 GPI13 GlycosylPhosphatidylInositol anchor biosynthesis 1017.0 0 0 0 0 -0.9698015019709862 Q07830 0.9473130106925964 0.9489949941635132 0.6347928047180176 0.378839910030365 41.19673014202391 40.0 0.0 no 7957 chrXII_79026 22779 essential YLL031C 1160 - TGTCCTTATATAATTGTAAT D|393|H D|393|N K|392|N silent|AAG>AAA|K|392 GPI13 GlycosylPhosphatidylInositol anchor biosynthesis 1017.0 0 0 0 0 -0.7152782375557578 Q07830 0.9486550092697144 0.956179976463318 0.9355990290641784 0.18954965472221372 0.5297251343727112 0.2508990168571472 36.208132486075954 20.0 0.0 no 7958 chrXII_79029r 22780 essential YLL031C 1154 + AAGCCAATTACAATTATATA S|386|R silent|AGC>AGT|S|386 Q|387|E Q|387|* GPI13 GlycosylPhosphatidylInositol anchor biosynthesis 1017.0 0 0 0 0 0.7739794083767438 Q07830 0.9417110085487366 0.9590039849281312 0.5194914340972899 0.0 34.399708520583204 20.0 0.0 no 7959 chrXII_79115r 22782 essential YLL031C 1068 + CCGATACCATTTAACAATCT P|357|R P|357|L P|359|A P|359|S GPI13 GlycosylPhosphatidylInositol anchor biosynthesis 1017.0 0 0 0 0 0.0063847182168527685 Q07830 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.03534019738435745 0.018098952248692516 0.0 0.0 42.29312091399714 35.0 0.0 no 7960 chrXII_79115 22783 essential YLL031C 1071 - CCAAGATTGTTAAATGGTAT G|364|R G|364|R GPI13 GlycosylPhosphatidylInositol anchor biosynthesis 1017.0 0 0 0 0 -4.5515073389524785 Q07830 0.941340982913971 0.941340982913971 0.0 0.0 38.24915302577113 30.0 0.0 yes 7961 chrXII_79170 22786 essential YLL031C 1016 - AATCAATTTGTCTCACTGAA D|345|H D|345|N GPI13 GlycosylPhosphatidylInositol anchor biosynthesis 1017.0 0 0 0 0 0.3328664367060496 Q07830 0.9486550092697144 0.956179976463318 0.0 0.0 38.63129506025536 30.0 0.0 no 7962 chrXII_79232 22787 essential YLL031C 954 - TCTTTAAGTCTCCACATGTC E|325|Q E|325|K GPI13 GlycosylPhosphatidylInositol anchor biosynthesis 1017.0 0 0 0 0 0.6635936197152335 Q07830 0.956179976463318 0.9475290179252625 0.5292885899543762 0.8712975382804871 47.48511440331356 40.0 0.0 no 7963 chrXII_79350r 22790 essential YLL031C 833 + GATCGATGATGATACCTTAT I|279|M silent|ATC>ATT|I|279 GPI13 GlycosylPhosphatidylInositol anchor biosynthesis 1017.0 0 0 0 0 0.2365009030907833 Q07830 0.9598389863967896 0.4938458204269409 41.634102363376094 35.0 0.0 no 7964 chrXII_79469r 22791 essential YLL031C 714 + GTCATGATTGGACACATGCT silent|GTC>GTG|V|239 silent|GTC>GTT|V|239 GPI13 GlycosylPhosphatidylInositol anchor biosynthesis 1017.0 0 0 0 0 -0.31348011242359913 Q07830 48.16769797525558 45.0 0.0 no 7965 chrXII_79506r 22793 essential YLL031C 677 + CTTCCATGATCATTTACAGC F|227|L silent|TTC>TTT|F|227 H|228|D H|228|Y GPI13 GlycosylPhosphatidylInositol anchor biosynthesis 1017.0 0 0 0 0 -0.3344408212859994 Q07830 0.9387490153312684 0.9473130106925964 0.9489949941635132 1.0 0.20390935242176056 1.0 46.42009411886885 40.0 0.0 no 7966 chrXII_79533r 22794 essential YLL031C 650 + TACTGTCGATAACGGTGTTA T|218|S T|218|I silent|GTC>GTG|V|219 silent|GTC>GTT|V|219 GPI13 GlycosylPhosphatidylInositol anchor biosynthesis 1017.0 0 0 0 0 1.5456300729184151 Q07830 0.9491789937019348 0.9472420215606691 0.09779279679059982 0.014726700261235237 43.65421448371495 40.0 0.0 no 7967 chrXII_79566 22797 essential YLL031C 620 - ACACATTGAGTGATTCTAGT V|213|L V|213|M silent|GTG>GTC|V|213 silent|GTG>GTA|V|213 GPI13 GlycosylPhosphatidylInositol anchor biosynthesis 1017.0 0 0 0 0 -0.32848799795640543 Q07830 0.9539830088615416 0.9587630033493042 0.19547991454601288 0.04092799127101898 42.98000166907923 35.0 0.0 no 7968 chrXII_79564r 22798 essential YLL031C 619 + CACTAGAATCACTCAATGTG L|208|V silent|CTA>TTA|L|208 GPI13 GlycosylPhosphatidylInositol anchor biosynthesis 1017.0 0 1 0 0 0.9484466568570455 Q07830 0.9512209892272948 0.35022956132888794 39.894019430462215 40.0 0.0 no 7969 chrXII_79579 22799 essential YLL031C 607 - TTCTAGTGGGAAACTATCGT E|209|Q E|209|K GPI13 GlycosylPhosphatidylInositol anchor biosynthesis 1017.0 0 0 0 0 0.21852446550687987 Q07830 0.956179976463318 0.9475290179252625 0.1932392716407776 0.2371716350317001 43.723566724357454 40.0 0.0 no 7970 chrXII_79763r 22804 essential YLL031C 420 + ACTACTTTACAAAGACTCAA T|141|S T|141|I T|142|S T|142|I GPI13 GlycosylPhosphatidylInositol anchor biosynthesis 1017.0 0 0 0 0 -2.7801689733090496 Q07830 0.9491789937019348 0.9472420215606691 0.9491789937019348 0.9472420215606691 0.5846365690231323 0.06817188113927841 0.2890715301036835 0.04448377713561058 36.541729227479664 30.0 0.0 yes 7971 chrXII_79797 22805 essential YLL031C 389 - CGGCAATGAACTTCAACAAT A|136|P A|136|T GPI13 GlycosylPhosphatidylInositol anchor biosynthesis 1017.0 0 0 0 0 0.3954951435275385 Q07830 0.9573720097541808 0.9523990154266356 0.02518886886537075 0.21051864326000214 40.115072066344624 40.0 0.0 no 7972 chrXII_79952 22808 essential YLL031C 234 - ATCACCGCCTTGTTGAACCT silent|GTG>GTC|V|84 silent|GTG>GTA|V|84 V|84|L V|84|M GPI13 GlycosylPhosphatidylInositol anchor biosynthesis 1017.0 0 0 0 0 -0.5909032513351119 Q07830 0.9539830088615416 0.9587630033493042 0.09696893393993378 0.16279925405979154 54.487228823657006 50.0 0.0 no 7973 chrXII_110501 22811 essential YLL018C 1055 - TCAACGTGTCCAAAACTTCG L|358|F silent|TTG>TTA|L|358 silent|ACG>ACC|T|357 silent|ACG>ACA|T|357 DPS1 557.0 0 0 0 0 0.2321458399270085 P04802 0.8715869784355164 0.17242743074893951 3.7699999809265137 43.20082340070866 45.0 0.0 no 7974 chrXII_110719 22817 essential YLL018C 837 - ACACTGGAACCACCTTCACT S|285|T S|285|N V|286|L V|286|M DPS1 557.0 0 0 0 0 -0.11214889673391316 P04802 0.9431989789009094 0.9769999980926514 0.8403769731521606 0.7161660194396973 0.15540538728237152 1.0 0.011012068949639795 0.003161765169352293 0.9172000288963318 -1.0532000064849854 2.036600112915039 -0.421999990940094 0.011939999647438526 0.00546000013127923 0.9418799877166748 -0.6314200162887573 51.54199030669389 50.0 0.0 no 7975 chrXII_110826 22820 essential YLL018C 730 - AATCCTGAAAATAGCTTGGT R|249|S silent|AGG>AGA|R|249 R|249|T R|249|K DPS1 557.0 0 0 0 0 0.6524470354557157 P04802 0.8810510039329529 0.8833280205726624 0.9531819820404052 0.1362200677394867 0.09577584266662598 0.5477180480957031 -0.3181999921798706 1.4947999715805054 -0.2303999960422516 0.4153200089931488 0.11456000059843065 -0.5866000056266785 41.32901445715197 35.0 0.0 no 7976 chrXII_110829r 22821 essential YLL018C 724 + TCACCAACCAAGCTATTTTC T|243|S T|243|I silent|GTC>GTG|V|242 silent|GTC>GTT|V|242 DPS1 557.0 0 0 0 0 0.3941888708472386 P04802 0.8789070248603821 0.7528150081634521 0.2203422635793686 0.09212585538625716 0.6837999820709229 -0.13079999387264252 46.368169514796314 40.0 0.0 no 7977 chrXII_110967 22828 essential YLL018C 589 - TGCTTCTGGAGTCTCGGAAA A|203|P A|203|T E|202|Q E|202|K DPS1 557.0 0 0 0 0 0.3207203160633756 P04802 0.9696800112724304 0.9632670283317566 0.9657279849052428 0.9408000111579896 0.27433255314826965 0.5673342347145081 0.6819295287132263 0.9020352959632874 1.688599944114685 -0.4181999862194061 0.04199999943375588 0.5989999771118164 2.032439947128296 -1.1136399507522583 49.5357760698401 50.0 0.0 no 7978 chrXII_110979 22829 essential YLL018C 577 - CTCGGAAATGGTATAAATCT E|199|Q E|199|K DPS1 557.0 0 1 0 0 0.21402561245984314 P04802 0.964830994606018 0.9445580244064332 0.3797109127044678 1.0 0.303600013256073 -0.2334000021219253 -0.04679999873042106 0.1977400034666061 37.95848821167624 35.0 0.0 no 7979 chrXII_111056 22834 essential YLL018C 500 - TCTTGACAATACCTCTGACA K|173|N silent|AAG>AAA|K|173 V|172|L V|172|I DPS1 557.0 0 0 0 0 -0.07258350800043503 P04802 0.8948919773101807 0.9364200234413148 0.9560970067977904 0.4495352208614349 0.163102388381958 0.12330387532711028 1.632200002670288 0.3562000095844269 0.3711999952793121 0.8923599720001221 -0.10091999918222427 45.04657576425421 40.0 0.0 no 7980 chrXII_111160r 22837 essential YLL018C 393 + CAACAAGCTTCCTTGATCCA Q|133|E Q|133|* DPS1 557.0 0 0 0 0 0.4988252388947717 P04802 0.8838570117950441 0.5083330273628235 -0.20319999754428866 1.1922800540924072 49.088195692508236 45.0 0.0 no 7981 chrXII_111239r 22838 essential YLL018C 314 + CGACAAAGAAGTCCTCTTCA D|106|E silent|GAC>GAT|D|106 DPS1 557.0 0 1 0 0 0.17647169571675192 P04802 0.9626539945602416 0.5202755331993103 0.5835999846458435 44.714390456549275 45.0 0.0 no 7982 chrXII_111398 22846 essential YLL018C 158 - CTTCTCTTTCAGCTTCCAAC E|59|Q E|59|K R|58|T R|58|K DPS1 557.0 0 0 0 0 -0.386917317066925 P04802 1.0141899585723877 0.9685410261154176 1.002310037612915 1.0367300510406494 0.564103364944458 0.8315934538841248 0.571385383605957 0.866780698299408 50.945995874813086 45.0 0.0 no 7983 chrXII_111456 22847 essential YLL018C 100 - CTCTTTCTGCAATTTCTTCA E|40|Q E|40|K Q|38|H silent|CAG>CAA|Q|38 DPS1 557.0 0 0 0 0 0.4466247911115101 P04802 0.9875779747962952 0.9766860008239746 0.8808720111846924 0.4050677418708801 0.8114663362503052 0.119981586933136 46.60461127483011 35.0 0.0 no 7984 chrXII_111472 22849 essential YLL018C 84 - TTCAAGGCCTTCTTGGACAA L|34|F silent|TTG>TTA|L|34 DPS1 557.0 0 1 0 0 0.8143003337185515 P04802 0.8875290155410767 0.3727026581764221 49.13390712312906 45.0 0.0 no 7985 chrXII_111506r 22850 essential YLL018C 47 + ACCTGCTCAAGTTATTCTTG P|17|R P|17|L P|17|A P|17|S DPS1 557.0 0 1 0 0 0.10345055293685346 P04802 0.9547060132026672 0.9605630040168762 0.982716977596283 0.977735996246338 0.21675114333629608 0.13381782174110413 0.4229318201541901 0.3200112879276276 47.27881387706299 40.0 0.0 no 7986 chrXII_127561 22852 essential YLL011W 38 + TGTCCCTGTTAAAAGTACGC silent|GTC>GTG|V|14 silent|GTC>GTT|V|14 P|15|A P|15|S SOF1 Suppressor Of Fibrillarin 489.0 0 0 0 0 1.2693445786353648 P33750 0.23968364298343656 0.20317770540714264 47.13189814164895 45.0 1.0 no 7987 chrXII_127536r 22853 essential YLL011W 16 - GTCATCAGCACTTCTTTTAA D|12|H D|12|N D|11|H D|11|N SOF1 Suppressor Of Fibrillarin 489.0 0 0 0 0 -0.08433476449049275 P33750 0.07372020930051804 0.4151809811592102 0.10451149195432664 0.424234539270401 45.458860620371176 35.0 1.0 no 7988 chrXII_127564r 22854 essential YLL011W 44 - ATTCCTGCGTACTTTTAACA E|21|Q E|21|K Q|20|H silent|CAG>CAA|Q|20 SOF1 Suppressor Of Fibrillarin 489.0 0 0 0 0 -0.01911927399404105 P33750 0.599642276763916 0.9202536344528198 0.019385112449526787 45.682175096567896 35.0 1.0 no 7989 chrXII_127609r 22856 essential YLL011W 89 - TTTCAAAAGGATGCAATTCA E|36|Q E|36|K SOF1 Suppressor Of Fibrillarin 489.0 0 0 0 0 -1.6698240477335775 P33750 0.11587244272232056 0.013145201839506626 37.58074078681966 30.0 1.0 no 7990 chrXII_127651 22857 essential YLL011W 128 + AGCTTTGAATGCCACCAAAT A|44|G A|44|V SOF1 Suppressor Of Fibrillarin 489.0 0 0 0 0 0.8450497232239115 P33750 0.0 0.0 46.164483256474114 40.0 1.0 no 7991 chrXII_127688 22858 essential YLL011W 165 + AAACCCTTTGTGGGTCAGTT P|57|A P|57|S P|57|R P|57|L SOF1 Suppressor Of Fibrillarin 489.0 0 0 0 0 0.29230918490522384 P33750 0.0 0.0 0.0 0.0 51.67390548513913 45.0 1.0 no 7992 chrXII_127691r 22859 essential YLL011W 171 - TATCCTAACTGACCCACAAA G|63|A G|63|E G|63|R G|63|R SOF1 Suppressor Of Fibrillarin 489.0 0 0 0 0 0.4242910142222216 P33750 0.12945394217967987 0.18303298950195312 0.08847319334745407 0.08847319334745407 44.84491642857671 40.0 1.0 no 7993 chrXII_127918r 22863 essential YLL011W 398 - TGCAAGATAACATAAAATTT C|139|S C|139|Y SOF1 Suppressor Of Fibrillarin 489.0 0 0 0 0 -0.3004560069496605 P33750 0.06270863860845566 0.007339941803365945 30.660546970132657 20.0 1.0 no 7994 chrXII_128051 22866 essential YLL011W 528 + GACGGTGAATCTGCATTTCA D|177|E silent|GAC>GAT|D|177 SOF1 Suppressor Of Fibrillarin 489.0 0 0 0 0 0.9011888716369499 P33750 0.6448657512664795 47.250513701147845 45.0 1.0 no 7995 chrXII_128094 22868 essential YLL011W 571 + ACTCCACGTTTGCCACAGGT S|192|C S|192|F N|191|K silent|AAC>AAT|N|191 SOF1 Suppressor Of Fibrillarin 489.0 0 0 0 0 -0.9618590365265216 P33750 0.04087807610630989 0.04147944226861 0.7593473792076111 57.778040003988345 55.00000000000001 1.0 no 7996 chrXII_128118r 22869 essential YLL011W 598 - AACGTCCCAAAGATGGATCT V|206|L V|206|I D|205|H D|205|N SOF1 Suppressor Of Fibrillarin 489.0 0 0 0 0 -0.8100718736876107 P33750 0.6552740335464478 0.39209112524986267 0.013360477052628994 0.21428270637989044 46.34417626899869 45.0 1.0 no 7997 chrXII_128125r 22870 essential YLL011W 605 - ATCTGTTAACGTCCCAAAGA R|208|T R|208|K SOF1 Suppressor Of Fibrillarin 489.0 0 0 0 0 -0.26604064155057283 P33750 0.004098679404705763 0.02392250671982765 45.10430203993269 40.0 1.0 no 7998 chrXII_128152 22871 essential YLL011W 629 + GCCAGTTTCCGATCTATCAT P|211|R P|211|L P|211|A P|211|S SOF1 Suppressor Of Fibrillarin 489.0 0 0 0 0 -1.794575851761731 P33750 0.002419902477413416 0.003324096091091633 0.1128971204161644 0.014952829107642176 53.02893901376666 45.0 1.0 no 7999 chrXII_128216 22874 essential YLL011W 693 + ACAGATATCTTGGCCAGTAC T|232|R T|232|I SOF1 Suppressor Of Fibrillarin 489.0 0 0 0 0 0.1850792478790912 P33750 0.2026859074831009 0.05871458724141121 48.61283061009556 45.0 1.0 no 8000 chrXII_128333r 22876 essential YLL011W 813 - ACAAAGTTGAAGGCCTCCAT V|278|L V|278|I SOF1 Suppressor Of Fibrillarin 489.0 0 0 0 0 0.07912482514675956 P33750 0.01407727971673012 0.016733512282371518 48.182526137848704 45.0 1.0 no 8001 chrXII_128376 22877 essential YLL011W 853 + ACGCCTACTATTATGATATG A|286|G A|286|V N|285|K silent|AAC>AAT|N|285 SOF1 Suppressor Of Fibrillarin 489.0 0 0 0 0 0.7502054803857694 P33750 0.004458259791135788 0.6469664573669434 0.005621288903057575 41.846302013968796 35.0 1.0 no 8002 chrXII_128379r 22878 essential YLL011W 859 - ATTCCTCATATCATAATAGT R|292|S silent|AGG>AGA|R|292 R|292|T R|292|K SOF1 Suppressor Of Fibrillarin 489.0 0 0 0 0 -1.866200372092571 P33750 0.0 0.0 0.0 39.968107579309454 25.0 1.0 no 8003 chrXII_128619 22880 essential YLL011W 1096 + GATCTGATGATGGGAATGTT S|367|C S|367|F SOF1 Suppressor Of Fibrillarin 489.0 0 0 0 0 0.3941130552213138 P33750 0.0 0.0 42.875513778261336 40.0 1.0 no 8004 chrXII_131801r 22881 essential YLL008W 75 - TCATCAGAAGAATCTAGAAT D|32|H D|32|N D|31|H D|31|N DRS1 Deficiency of Ribosomal Subunits 752.0 0 1 0 0 0.4830867946412204 P32892 0.130416139960289 0.3290219306945801 0.093837209045887 0.3782949149608612 35.39304106816297 30.0 1.0 no 8005 chrXII_131770r 22883 essential YLL008W 44 - CTTCACTGTCACTGATTGTA E|21|Q E|21|K S|20|T S|20|N DRS1 Deficiency of Ribosomal Subunits 752.0 0 1 0 0 0.0943782386708522 P32892 0.0230066291987896 0.017854273319244385 0.059866327792406075 0.9898829460144044 46.501743178489725 40.0 1.0 no 8006 chrXII_131771r 22884 essential YLL008W 45 - TCTTCACTGTCACTGATTGT D|22|H D|22|N E|21|Q E|21|K DRS1 Deficiency of Ribosomal Subunits 752.0 0 1 0 0 -0.2680688258080104 P32892 0.03288611397147178 0.5237779021263123 0.0230066291987896 0.017854273319244385 48.221644108640355 40.0 1.0 no 8007 chrXII_131967 22892 essential YLL008W 238 + CCACTTCGAACTTCCAAGGC T|81|S T|81|I silent|ACC>ACG|T|80 silent|ACC>ACT|T|80 DRS1 Deficiency of Ribosomal Subunits 752.0 0 0 0 0 -0.6518541737161394 P32892 0.7441598773002625 0.20046350359916687 51.563026659606244 55.00000000000001 1.0 no 8008 chrXII_132012r 22895 essential YLL008W 286 - AGCTTCGGCATCGTCCTTAT A|102|P A|102|T E|101|Q E|101|K DRS1 Deficiency of Ribosomal Subunits 752.0 0 0 0 0 -0.7340820992167182 P32892 0.27357545495033264 0.5764206647872925 0.5900273323059082 0.9624915719032288 55.71132764644125 50.0 1.0 no 8009 chrXII_132100r 22896 essential YLL008W 374 - CTTCTTGTTTACTATCAATA E|131|Q E|131|K DRS1 Deficiency of Ribosomal Subunits 752.0 0 1 0 0 -0.07912509045358554 P32892 0.2478737682104111 0.3941692411899567 38.54065228039798 25.0 1.0 no 8010 chrXII_132099r 22897 essential YLL008W 373 - TTCTTGTTTACTATCAATAT E|131|Q E|131|K DRS1 Deficiency of Ribosomal Subunits 752.0 0 1 0 0 0.14434999602955806 P32892 0.2478737682104111 0.3941692411899567 36.6485560423713 20.0 1.0 no 8011 chrXII_132371 22901 essential YLL008W 642 + TTCTATGCGCCTGAAACTGA F|215|L silent|TTC>TTT|F|215 DRS1 Deficiency of Ribosomal Subunits 752.0 0 0 0 0 0.4150647367811661 P32892 0.08845915645360948 47.35303167659134 45.0 1.0 no 8012 chrXII_132380r 22902 essential YLL008W 654 - GCTTCATCTCCCTCAGTTTC A|225|P A|225|T E|224|Q E|224|K DRS1 Deficiency of Ribosomal Subunits 752.0 0 0 0 0 -0.4204834040878058 P32892 0.18762370944023127 0.6725575923919678 0.5432920455932617 0.9067222476005554 58.288911966146316 50.0 1.0 no 8013 chrXII_132454 22903 essential YLL008W 725 + TCTTAAGGGCCTTGCAAGTT L|243|V L|243|F DRS1 Deficiency of Ribosomal Subunits 752.0 0 0 0 0 0.27559536492217057 P32892 0.01824851892888546 0.016593461856245998 51.0151470348809 45.0 1.0 no 8014 chrXII_132508 22904 essential YLL008W 779 + CACAATCCCCATTGCCTTAT T|261|R T|261|I I|262|M silent|ATC>ATT|I|262 DRS1 Deficiency of Ribosomal Subunits 752.0 0 0 0 0 0.4067316357388978 P32892 0.004352067597210407 0.004844720009714365 0.0028552005533128977 53.159201546514396 45.0 1.0 no 8015 chrXII_132509 22905 essential YLL008W 780 + ACAATCCCCATTGCCTTATT T|261|R T|261|I I|262|M silent|ATC>ATT|I|262 DRS1 Deficiency of Ribosomal Subunits 752.0 0 0 0 0 0.5497653939761178 P32892 0.004352067597210407 0.004844720009714365 0.0028552005533128977 52.27903601418842 40.0 1.0 no 8016 chrXII_132515r 22906 essential YLL008W 789 - TCTTTACCCAATAAGGCAAT D|270|H D|270|N G|268|A G|268|D DRS1 Deficiency of Ribosomal Subunits 752.0 0 0 0 0 0.8743716618211863 P32892 0.0 0.0 0.0 0.0 43.8001661768638 35.0 1.0 no 8017 chrXII_132539 22908 essential YLL008W 810 + ATCATTGCCGGTGCTGTGAC I|271|M silent|ATC>ATT|I|271 DRS1 Deficiency of Ribosomal Subunits 752.0 0 0 0 0 0.23310425806467394 P32892 0.013268627226352692 55.107842289356306 55.00000000000001 1.0 no 8018 chrXII_132546r 22910 essential YLL008W 820 - ACCGGAACCAGTCACAGCAC G|280|R G|280|S G|280|A G|280|D DRS1 Deficiency of Ribosomal Subunits 752.0 0 0 0 0 -5.080564145703532 P32892 0.0 0.0 0.0 0.0 54.031802160817854 60.0 1.0 yes 8019 chrXII_132590r 22911 essential YLL008W 864 - TACAACAAACGCTCGATTAT L|294|F silent|TTG>TTA|L|294 L|293|F silent|TTG>TTA|L|293 DRS1 Deficiency of Ribosomal Subunits 752.0 0 0 0 0 0.7458015261819755 P32892 0.0 0.0 38.71072304418959 35.0 1.0 no 8020 chrXII_132591r 22912 essential YLL008W 865 - ATACAACAAACGCTCGATTA L|294|F silent|TTG>TTA|L|294 L|293|F silent|TTG>TTA|L|293 DRS1 Deficiency of Ribosomal Subunits 752.0 0 0 0 0 0.5123523975909693 P32892 0.0 0.0 38.71072304418959 35.0 1.0 no 8021 chrXII_132710 22915 essential YLL008W 981 + TTCGTCTCCGGTATAACCTT F|328|L silent|TTC>TTT|F|328 silent|GTC>GTG|V|329 silent|GTC>GTT|V|329 DRS1 Deficiency of Ribosomal Subunits 752.0 0 0 0 0 -0.3924882142616438 P32892 0.0902182161808014 51.505176690926476 45.0 1.0 no 8022 chrXII_132738r 22918 essential YLL008W 1012 - TCTCAAGTTCAAACCACCAA L|343|F silent|TTG>TTA|L|343 R|344|T R|344|K DRS1 Deficiency of Ribosomal Subunits 752.0 0 0 0 0 -0.290144959273181 P32892 0.08017119020223618 0.008769462816417217 1.0 44.587144180544946 40.0 1.0 no 8023 chrXII_132791 22919 essential YLL008W 1062 + GACATCGTCATTGCTACCCC D|355|E silent|GAC>GAT|D|355 I|356|M silent|ATC>ATT|I|356 DRS1 Deficiency of Ribosomal Subunits 752.0 0 0 0 0 0.6243623317708658 P32892 0.0 0.005742799025028944 55.99471853090404 55.00000000000001 1.0 no 8024 chrXII_132835 22920 essential YLL008W 1106 + GAACTCAGCAAGTTTTAATG N|370|K silent|AAC>AAT|N|370 S|371|* S|371|L DRS1 Deficiency of Ribosomal Subunits 752.0 0 0 0 0 -2.258520066304605 P32892 0.0 0.007660809438675642 38.35435175877944 35.0 1.0 yes 8025 chrXII_132940r 22923 essential YLL008W 1214 - TCTGTCTATTGCTTGGTAAT Q|411|H silent|CAG>CAA|Q|411 R|410|T R|410|K DRS1 Deficiency of Ribosomal Subunits 752.0 0 0 0 0 0.026193141199065708 P32892 0.0 0.0 0.0 45.68745464873331 35.0 1.0 no 8026 chrXII_132990r 22924 essential YLL008W 1264 - ACTAACTAAACTTTTAATTT S|428|T S|428|N V|427|L V|427|I DRS1 Deficiency of Ribosomal Subunits 752.0 0 1 0 0 0.4638540797725641 P32892 0.017254490405321118 0.015410707332193853 0.01866577193140984 1.0 30.57285316557528 15.0 1.0 no 8027 chrXII_133122 22927 essential YLL008W 1393 + CCTTGTTATTTAATTTGATT silent|GCC>GCG|A|465 silent|GCC>GCT|A|465 DRS1 Deficiency of Ribosomal Subunits 752.0 0 0 0 0 -0.4860101300912449 P32892 37.832308080486996 20.0 1.0 no 8028 chrXII_133154r 22929 essential YLL008W 1428 - ACAATCCTCTTTTGACCCGT V|483|L V|483|I R|481|S silent|AGG>AGA|R|481 DRS1 Deficiency of Ribosomal Subunits 752.0 0 0 0 0 0.13207264345681227 P32892 0.022373178973793983 1.0 0.06767763942480087 52.35490226363822 45.0 1.0 no 8029 chrXII_133354 22932 essential YLL008W 1625 + TCTTGATATCCCCAAGATTG L|543|V L|543|F DRS1 Deficiency of Ribosomal Subunits 752.0 0 0 0 0 0.209275764180666 P32892 0.009105375036597252 0.00820249877870083 46.68063498036946 40.0 1.0 no 8030 chrXII_136611r 22933 high_effect YLL006W 28 - CGTCATTAACGAATCCGTTT M|15|I M|15|I 0 0 0 0 0.7002346076594389 P41800 0.9553959965705872 0.9553959965705872 43.98924688996476 40.0 1.0 no 8031 chrXII_136823r 22935 high_effect YLL006W 240 - GCTAACGATCCTAACGAAGA A|87|P A|87|T silent|TCG>TCC|S|85 silent|TCG>TCA|S|85 0 0 0 0 -0.6761224777632122 P41800 0.9573720097541808 0.9523990154266356 0.32483819127082825 0.5928326249122621 42.92941130350232 45.0 1.0 no 8032 chrXII_136844 22937 high_effect YLL006W 258 + GCAACGTCCTCCAAATTTTC A|87|G A|87|V T|88|R T|88|M 0 0 0 0 0.4929617976027789 P41800 0.9484469890594482 0.9504740238189696 0.9476869702339172 0.9502379894256592 0.4252339005470276 0.3385029137134552 0.5611574649810791 0.14251719415187836 48.13755894000382 45.0 1.0 no 8033 chrXII_136930r 22938 high_effect YLL006W 347 - CACTGAATATAAAGAACTTT S|122|T S|122|N 0 0 0 0 0.5665919517331122 P41800 0.9512869715690612 0.9536849856376648 0.6947193741798401 0.09672081470489502 32.002444157885634 25.0 1.0 no 8034 chrXII_136958r 22939 high_effect YLL006W 375 - TTCGGATTCTTACTTTTAGA silent|CCG>CCC|P|131 silent|CCG>CCA|P|131 0 0 0 0 -0.08013800296661093 P41800 41.76303475289285 30.0 1.0 no 8035 chrXII_137041 22942 high_effect YLL006W 455 + CCTGACTTCTCTTGTTAGGA L|153|V silent|CTG>TTG|L|153 T|154|S T|154|I 0 0 0 0 0.31464913099838066 P41800 0.9512209892272948 0.9491789937019348 0.9472420215606691 0.2902231514453888 0.8197734951972961 0.19180628657341006 50.75805799100096 45.0 1.0 no 8036 chrXII_137041r 22943 high_effect YLL006W 458 - CCTTCCTAACAAGAGAAGTC K|159|N silent|AAG>AAA|K|159 R|158|S silent|AGG>AGA|R|158 0 0 0 0 -2.1089523628904923 P41800 0.9355990290641784 0.9087679982185364 0.4974754452705383 0.7070714831352234 44.54847678888109 45.0 1.0 yes 8037 chrXII_137221r 22951 high_effect YLL006W 638 - CCCTGTGCCAAGCCTCACTG R|219|T R|219|K R|219|S silent|AGG>AGA|R|219 0 0 0 0 -0.7084896308683856 P41800 0.932735025882721 0.955805003643036 0.9087679982185364 0.4357213377952576 1.0 0.769408643245697 61.684437881188565 65.0 1.0 no 8038 chrXII_137259r 22952 high_effect YLL006W 676 - TCTTCCAATAAAATCATTCA R|232|T R|232|K G|231|A G|231|E 0 1 0 0 0.1567387512036471 P41800 0.932735025882721 0.955805003643036 0.9499930143356324 0.9438679814338684 0.3584436476230621 1.0 0.4600984156131744 0.5311003923416138 37.089956062478215 25.0 1.0 no 8039 chrXII_137372 22954 high_effect YLL006W 786 + ATACAATATTCGCCAAATTC Q|264|E Q|264|* 0 0 0 0 0.3321360664341848 P41800 0.9590039849281312 0.6642099618911743 38.4168988089844 30.0 1.0 no 8040 chrXII_137384r 22955 high_effect YLL006W 801 - AGCTTTTTATTTCCTGAATT K|273|N silent|AAG>AAA|K|273 0 0 0 0 0.5591959144894467 P41800 0.9355990290641784 0.29137641191482544 42.31014786622074 25.0 1.0 no 8041 chrXII_137437r 22956 high_effect YLL006W 854 - TTTCTACTCCTAAAGTTAAG E|291|Q E|291|K V|290|L V|290|I 0 0 0 0 0.3237151816888042 P41800 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.03433917835354805 0.02862967737019062 0.11188144236803056 0.5665249824523926 38.141907456207264 30.0 1.0 no 8042 chrXII_137468 22957 high_effect YLL006W 882 + TTACTTAACTATCCAAAGCC L|296|V L|296|F 0 0 0 0 -0.23355346742754385 P41800 0.9512209892272948 0.9587849974632264 0.022564569488167763 0.016483070328831673 41.91577148956822 35.0 1.0 no 8043 chrXII_141081r 22960 essential YLL004W 11 - TCATCTTTTTGGATTGGTTA M|10|I M|10|I K|9|N silent|AAG>AAA|K|9 ORC3 Origin Recognition Complex 616.0 0 0 0 0 1.0370706198482915 P54790 0.9994800090789796 0.9994800090789796 0.9806249737739564 43.797114008523465 30.0 1.0 no 8044 chrXII_141110 22961 essential YLL004W 37 + GCGAGTTTGCTGACGCCCAA S|13|R silent|AGC>AGT|S|13 ORC3 Origin Recognition Complex 616.0 0 0 0 0 0.5279414536021247 P54790 0.9058769941329956 56.81111958509308 60.0 1.0 no 8045 chrXII_141126r 22962 essential YLL004W 56 - ATACTGTATAGTGGCTCCTT V|25|L V|25|I ORC3 Origin Recognition Complex 616.0 0 0 0 0 0.07654531494539421 P54790 0.9131360054016112 0.9208049774169922 0.991984486579895 0.7257361412048341 50.06637531439218 40.0 1.0 no 8046 chrXII_141201 22965 essential YLL004W 128 + ACTTCTATCAGGCAAAGAAT L|44|V L|44|F L|45|V silent|CTA>TTA|L|45 ORC3 Origin Recognition Complex 616.0 0 0 0 0 -0.5907384346846116 P54790 0.9948729872703552 1.002940058708191 0.9950990080833436 0.0 0.0 0.04587797820568085 40.49318934006044 35.0 1.0 no 8047 chrXII_141390r 22966 essential YLL004W 320 - TCGTACTATCTGAACCTAAT silent|ACG>ACC|T|113 silent|ACG>ACA|T|113 S|112|T S|112|N ORC3 Origin Recognition Complex 616.0 0 0 0 0 0.0875496888644032 P54790 0.9914429783821106 0.99549400806427 1.0 0.2352111041545868 41.76644204341295 35.0 1.0 no 8048 chrXII_141615 22968 essential YLL004W 542 + ATCATACGATCTGTCACTTG S|182|* S|182|L Y|183|* silent|TAC>TAT|Y|183 ORC3 Origin Recognition Complex 616.0 0 0 0 0 -3.1186642003796936 P54790 0.9753659963607788 0.27368101477622986 43.973889865027616 40.0 1.0 yes 8049 chrXII_141699 22969 essential YLL004W 626 + TTCTATTAACTTCAACACAT S|210|C S|210|F ORC3 Origin Recognition Complex 616.0 0 0 0 0 -0.14154287703624674 P54790 0.9879119992256165 0.9685909748077391 0.030049478635191917 0.017609141767024994 36.87231658052463 25.0 1.0 no 8050 chrXII_141906r 22970 essential YLL004W 836 - CCAAAAAGCTTTGAAAGATT L|285|F silent|TTG>TTA|L|285 ORC3 Origin Recognition Complex 616.0 0 0 0 0 -0.6252872486248837 P54790 1.002940058708191 0.3004902899265289 35.34717895858381 30.0 1.0 no 8051 chrXII_141919 22971 essential YLL004W 846 + AGCTTTTTGGATACGGTTGA S|283|R silent|AGC>AGT|S|283 ORC3 Origin Recognition Complex 616.0 0 0 0 0 0.7213475345858251 P54790 0.973734974861145 0.19324377179145813 46.93445527356504 40.0 1.0 no 8052 chrXII_142089r 22972 essential YLL004W 1019 - TCAAAAAATCAACATTTACA L|346|F silent|TTG>TTA|L|346 ORC3 Origin Recognition Complex 616.0 0 0 0 0 -0.102549574030409 P54790 1.0031700134277344 0.21431171894073486 30.134748675291352 20.0 1.0 no 8053 chrXII_142090r 22973 essential YLL004W 1020 - TTCAAAAAATCAACATTTAC L|346|F silent|TTG>TTA|L|346 ORC3 Origin Recognition Complex 616.0 0 0 0 0 0.594675804544957 P54790 1.0031700134277344 0.21431171894073486 29.034759173007444 20.0 1.0 no 8054 chrXII_142147 22974 essential YLL004W 1074 + ACATTCATGTTCTTTGTCGA T|359|R T|359|I F|360|L silent|TTC>TTT|F|360 ORC3 Origin Recognition Complex 616.0 0 0 0 0 0.4551374117432374 P54790 0.9771119952201844 0.9891359806060792 0.982241988182068 0.01647293195128441 0.01762337051331997 0.0 45.627826269594834 35.0 1.0 no 8055 chrXII_142233r 22976 essential YLL004W 1163 - ACTCAACAAAAAACTCTTCT E|394|Q E|394|K E|394|D silent|GAG>GAA|E|394 ORC3 Origin Recognition Complex 616.0 0 0 0 0 0.5505119839143701 P54790 1.0004899501800537 0.9891330003738404 0.9933249950408936 0.1487863063812256 0.18264807760715485 0.44374343752861023 35.42294592243553 30.0 1.0 no 8056 chrXII_142272r 22977 essential YLL004W 1202 - ACTTAGCATGCCCGTTAATC K|407|N silent|AAG>AAA|K|407 A|406|P A|406|T ORC3 Origin Recognition Complex 616.0 0 0 0 0 0.4233700684859988 P54790 0.9806249737739564 1.0011199712753296 0.9935200214385986 0.17994534969329834 0.10958971828222276 0.3039378821849823 50.287006648865315 45.0 1.0 no 8057 chrXII_142273r 22978 essential YLL004W 1203 - AACTTAGCATGCCCGTTAAT K|407|N silent|AAG>AAA|K|407 ORC3 Origin Recognition Complex 616.0 0 0 0 0 0.2089050333940464 P54790 0.9806249737739564 0.17994534969329834 47.722384069915 40.0 1.0 no 8058 chrXII_142385r 22979 essential YLL004W 1315 - TGCTGACCAACGATCTAGAT A|445|P A|445|T W|443|C W|443|* ORC3 Origin Recognition Complex 616.0 0 0 0 0 1.0333413716182422 P54790 0.920873999595642 0.912581980228424 0.9440850019454956 0.2036633938550949 0.3723967075347901 0.0765090361237526 46.2813279727788 45.0 1.0 no 8059 chrXII_142401 22980 essential YLL004W 1328 + GTCAGCATGTAAAGAGTATA S|444|* S|444|L A|445|G A|445|V ORC3 Origin Recognition Complex 616.0 0 0 0 0 -1.5581803436839152 P54790 0.9753659963607788 0.9109870195388794 0.9102140069007874 0.3627614378929138 0.5425459146499634 0.4008226692676544 40.535972285856985 35.0 1.0 no 8060 chrXII_142442r 22981 essential YLL004W 1372 - CTCTTGAAAAATTGTATCAA E|464|Q E|464|K ORC3 Origin Recognition Complex 616.0 0 0 0 0 -1.266188384454815 P54790 0.9840490221977234 0.972000002861023 0.08063357323408127 0.07383646070957184 33.0928249280102 25.0 1.0 no 8061 chrXII_143286r 22985 essential YLL003W 88 - TTGCTTGATGAGTACATCAG K|35|N silent|AAG>AAA|K|35 0 1 0 0 -4.912975947154768 Q12369 0.9327739477157592 43.72362388431446 40.0 1.0 yes 8062 chrXII_143325r 22986 essential YLL003W 127 - TCCATGAATTAGTGATTCGG G|49|R G|49|R G|49|A G|49|E 0 1 0 0 -2.4863225080728086 Q12369 0.6980746984481812 0.6980746984481812 0.6258049011230469 0.543258786201477 43.440648544757146 40.0 1.0 yes 8063 chrXII_143381r 22990 essential YLL003W 183 - TCAGTTTTATTTAATTCTAT E|68|Q E|68|K 0 0 0 0 0.6586612436257024 Q12369 0.5933104157447815 0.9290751218795776 34.7472208116605 15.0 1.0 no 8064 chrXII_143425 22991 essential YLL003W 224 + GTTCCATCTTCCTTCTCCAC F|76|L silent|TTC>TTT|F|76 H|77|D H|77|Y 0 1 0 0 0.3420596625689831 Q12369 0.6534667611122131 0.6173189282417297 0.281556248664856 58.42568992803393 50.0 1.0 no 8065 chrXII_143443 22994 essential YLL003W 242 + ACCGGTTGATTCGACAAATC P|82|R P|82|L P|82|A P|82|S 0 1 0 0 0.2446933685070836 Q12369 0.07245578616857529 0.7725668549537659 0.3504165709018707 0.0970236212015152 44.51550247018496 45.0 1.0 no 8066 chrXII_143489r 22995 essential YLL003W 291 - TCATATCGTAAACCATTCTT D|104|H D|104|N R|102|P R|102|Q 0 1 0 0 0.08695262289031959 Q12369 0.11324747651815414 1.0 0.3264830708503723 0.5406475067138672 41.165325388345934 30.0 1.0 no 8067 chrXII_143551r 22997 essential YLL003W 353 - CCAAAAAAGCTTCAATCTGG L|124|F silent|TTG>TTA|L|124 0 0 0 0 -0.08745838291558211 Q12369 0.0 39.216798524930255 40.0 1.0 no 8068 chrXII_143554r 22998 essential YLL003W 356 - GAACCAAAAAAGCTTCAATC V|125|L V|125|I L|124|F silent|TTG>TTA|L|124 0 0 0 0 -1.003501757035402 Q12369 1.0 0.7511510252952576 0.0 35.72915929949073 35.0 1.0 no 8069 chrXII_143621 22999 essential YLL003W 420 + GTCAATATTCTTATTCAAGA silent|GTC>GTG|V|141 silent|GTC>GTT|V|141 0 0 0 0 0.11130151268920437 Q12369 36.80044319710464 25.0 1.0 no 8070 chrXII_143752r 23000 essential YLL003W 554 - ATGCAATGAATTTGTTGCGA A|191|P A|191|T 0 0 0 0 -1.6263951678649005 Q12369 0.10638204962015152 0.18301229178905487 41.90066218102993 35.0 1.0 no 8071 chrXII_143793r 23001 essential YLL003W 595 - TCTGATTTTGTTCTTAGCGT R|205|T R|205|K 0 0 0 0 -0.056727288915018985 Q12369 0.3511696457862854 1.0 46.92261446641397 35.0 1.0 no 8072 chrXII_143811 23002 essential YLL003W 610 + TCAGAAGACATTTTAATCAC I|204|M silent|ATC>ATT|I|204 0 0 0 0 0.08767943346229418 Q12369 0.26698660850524897 35.788678048311056 30.0 1.0 no 8073 chrXII_143872 23004 essential YLL003W 671 + TGCAAATCAAGCAAAGCTGA A|225|G A|225|V 0 0 0 0 1.328376125110574 Q12369 0.40455320477485657 0.19728519022464752 40.95800906113408 40.0 1.0 no 8074 chrXII_143929 23006 essential YLL003W 728 + AACATTAAAATACTCACAGA T|244|R T|244|I 0 0 0 0 0.6503092293275136 Q12369 0.4732415974140167 0.4406640529632568 32.65947483756753 25.0 1.0 no 8075 chrXII_144016 23008 essential YLL003W 815 + AACTTTAACACAAACTCTTA T|273|S T|273|I 0 0 0 0 0.18676444492015049 Q12369 0.39707306027412415 0.05214515700936317 34.41285907802495 25.0 1.0 no 8076 chrXII_144063 23011 essential YLL003W 862 + CCTTTTTGAATAAGATGTTT silent|GCC>GCG|A|288 silent|GCC>GCT|A|288 0 0 0 0 0.44435178568077294 Q12369 38.005191731638654 25.0 1.0 no 8077 chrXII_144159 23012 essential YLL003W 958 + TACGAACAACATTTCATATA R|321|G R|321|* T|322|R T|322|I 0 0 0 0 -0.4256106263441388 Q12369 0.18030419945716855 0.6812993288040161 0.185808926820755 34.59540897688703 25.0 1.0 no 8078 chrXII_144621 23016 essential YLL003W 1420 + TCAAAGCAAGCGATTATTCG silent|CTC>CTG|L|474 silent|CTC>CTT|L|474 A|476|G A|476|V 0 0 0 0 1.1495765972526573 Q12369 0.0 0.0 40.699035632729476 40.0 1.0 no 8079 chrXII_144544 23017 essential YLL003W 1343 + TTCAATTGTAAGTCTAAAAG S|449|* S|449|L 0 0 0 0 0.04399488517782285 Q12369 0.04278629645705223 31.73229857330938 25.0 1.0 no 8080 chrXII_144654 23018 essential YLL003W 1453 + TCAAGTCATCATTGCGAAGT silent|CTC>CTG|L|485 silent|CTC>CTT|L|485 S|487|* S|487|L 0 0 0 0 0.8517765882301616 Q12369 0.3953617215156555 44.58008950579653 40.0 1.0 no 8081 chrXII_144928r 23022 essential YLL003W 1730 - CCAATTCCTTAGTTTTAATC L|583|F silent|TTG>TTA|L|583 E|582|Q E|582|K 0 0 0 0 0.06487022232232678 Q12369 0.16393135488033295 0.4298888146877289 0.5997574329376221 41.76317936495417 30.0 1.0 no 8082 chrXII_144981 23023 essential YLL003W 1780 + ATGCAATTTTGACTGTAAAA A|595|G A|595|V 0 0 0 0 0.8893819083326411 Q12369 0.1282506138086319 0.4197561144828797 35.031516046322224 25.0 1.0 no 8083 chrXII_145027 23024 essential YLL003W 1826 + TCATTTGCTATATACGAAAC H|610|D H|610|Y 0 0 0 0 -0.13713218288657486 Q12369 0.607638955116272 0.3013140559196472 36.63094029981494 30.0 1.0 no 8084 chrXII_145039 23025 essential YLL003W 1838 + TACGAAACTGGCGCCCTCTA T|614|R T|614|M 0 0 0 0 0.5700491403712576 Q12369 0.5040780901908875 0.19705085456371307 52.48567757019424 55.00000000000001 1.0 no 8085 chrXII_145052r 23026 essential YLL003W 1854 - AGCTTTACTCTATCCATAGA K|624|N silent|AAG>AAA|K|624 0 1 0 0 -2.5311288338965103 Q12369 0.4946417808532715 46.18162131445683 35.0 1.0 yes 8086 chrXII_145083r 23028 essential YLL003W 1885 - GGCTTTCCGCCACTTTAAAA A|635|P A|635|T silent|CGG>CGC|R|633 silent|CGG>CGA|R|633 0 0 0 0 -1.327408541530527 Q12369 0.2536817789077759 0.4960592389106751 49.64116418085155 45.0 1.0 no 8087 chrXII_145104r 23030 essential YLL003W 1906 - ATGCCTGACTTTGAACCTTG R|641|S silent|AGG>AGA|R|641 R|641|T R|641|K 0 0 0 0 0.30017252231107205 Q12369 0.675000786781311 0.5853404998779297 1.0 48.39663316282986 45.0 1.0 no 8088 chrXII_145258 23033 essential YLL003W 2057 + AAACTACCAGCTTGAAAAAA N|687|K silent|AAC>AAT|N|687 Y|688|* silent|TAC>TAT|Y|688 0 0 0 0 -0.11936711513734125 Q12369 0.45038187503814703 34.617186565988106 30.0 1.0 no 8089 chrXII_155044r 23036 essential YLR002C 1268 + AACACTCATTGGATCGGTTT T|424|R T|424|I L|425|V L|425|F NOC3 NucleOlar Complex associated 663.0 0 0 0 0 0.3545138384171615 Q07896 0.9476869702339172 0.9472420215606691 0.9512209892272948 0.9587849974632264 0.5226538181304932 0.1885308176279068 0.0 0.0 45.52205139502008 40.0 0.0 no 8090 chrXII_155050r 23037 essential YLR002C 1262 + TGCAAAAACACTCATTGGAT A|422|G A|422|V NOC3 NucleOlar Complex associated 663.0 0 0 0 0 0.6365568201337408 Q07896 0.9484469890594482 0.9504740238189696 0.3343261182308197 0.5106434822082521 38.820102682596776 35.0 0.0 no 8091 chrXII_155271 23039 essential YLR002C 1044 - TTACCTTTCAATTTAGTATT G|354|A G|354|D G|354|R G|354|S NOC3 NucleOlar Complex associated 663.0 0 0 0 0 -0.5708991980860416 Q07896 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.579663872718811 0.5503926873207092 0.4320758879184723 0.5152803063392639 38.45439732654097 20.0 0.0 no 8092 chrXII_155548r 23042 essential YLR002C 764 + CGCAAAAGAATTGATTTCAA A|256|G A|256|V NOC3 NucleOlar Complex associated 663.0 0 0 0 0 0.43796944975305496 Q07896 0.9484469890594482 0.9504740238189696 0.055914539843797684 0.6579721570014954 34.77750269327089 30.0 0.0 no 8093 chrXII_155589r 23043 essential YLR002C 723 + GCTCCTATACAGGTTTCATT P|243|A P|243|S A|242|G A|242|V NOC3 NucleOlar Complex associated 663.0 0 0 0 0 0.4561827255214556 Q07896 0.9562489986419678 0.9498909711837769 0.9484469890594482 0.9504740238189696 0.44418632984161377 0.5706652998924255 0.2797585129737854 0.2171579748392105 50.4070474020491 40.0 0.0 no 8094 chrXII_155859 23046 essential YLR002C 456 - AACGCAGCAGTATTTTCTTC silent|GCG>GCC|A|158 silent|GCG>GCA|A|158 A|158|P A|158|T NOC3 NucleOlar Complex associated 663.0 0 0 0 0 0.5360562058070417 Q07896 0.9573720097541808 0.9523990154266356 0.34584841132164 0.7017242312431335 46.28018095613214 40.0 0.0 no 8095 chrXII_156030 23047 essential YLR002C 285 - TCTTCCTCATCATCGTCCTT D|102|H D|102|N E|101|Q E|101|K NOC3 NucleOlar Complex associated 663.0 0 1 0 0 -0.09186546690280242 Q07896 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.12880241870880127 0.4785182476043701 0.2988956868648529 0.3433679938316345 55.70450405725467 45.0 0.0 no 8096 chrXII_156084 23048 essential YLR002C 231 - ACTTTACCGTTAACTTTTAT V|84|L V|84|I G|82|A G|82|D NOC3 NucleOlar Complex associated 663.0 0 0 0 0 -0.02990431962058361 Q07896 0.9539830088615416 0.9574310183525084 0.9499930143356324 0.9446240067481996 0.3674412667751312 0.8677260279655457 0.09398364275693892 0.6559176445007324 40.322663100188215 25.0 0.0 no 8097 chrXII_156220 23050 essential YLR002C 95 - CCATATCTTCCGGTGCATTT M|38|I M|38|I D|37|H D|37|N NOC3 NucleOlar Complex associated 663.0 0 0 0 0 -0.8990069353628486 Q07896 0.9553959965705872 0.9553959965705872 0.9486550092697144 0.956179976463318 0.22389215230941767 0.22389215230941767 0.11415841430425645 0.486713320016861 53.173003331263196 45.0 0.0 no 8098 chrXII_156252r 23052 essential YLR002C 60 + CACGAAGATTCCTTGTTAGA H|21|Q silent|CAC>CAT|H|21 NOC3 NucleOlar Complex associated 663.0 0 1 0 0 0.8453532369644249 Q07896 0.9588389992713928 0.5213378071784973 43.8550137923686 40.0 0.0 no 8099 chrXII_155727 23054 essential YLR002C 588 - TTCTTTTCAGTTTCAGTTAG K|202|N silent|AAG>AAA|K|202 NOC3 NucleOlar Complex associated 663.0 0 0 0 0 -0.342478419528205 Q07896 0.9355990290641784 0.013501343317329884 42.91001158163947 30.0 0.0 no 8100 chrXII_160120 23055 essential YLR005W 71 + ACAAGTTCATTTTGATGGCG Q|25|E Q|25|* SSL1 Suppressor of Stem-Loop mutation 461.0 0 0 0 0 -0.2944931678326218 Q04673 0.9583972692489624 43.873344806876155 40.0 1.0 no 8101 chrXII_160232 23057 essential YLR005W 183 + CTCTCGAATAGAAACCTGCA silent|CTC>CTG|L|62 silent|CTC>CTT|L|62 S|63|W S|63|L SSL1 Suppressor of Stem-Loop mutation 461.0 0 0 0 0 0.4705950644156279 Q04673 0.015658393502235413 0.2753457129001617 44.494375974143054 45.0 1.0 no 8102 chrXII_160388 23061 essential YLR005W 339 + AACATAACGCCATACCAAAG N|114|K silent|AAC>AAT|N|114 SSL1 Suppressor of Stem-Loop mutation 461.0 0 0 0 0 0.2721652897706859 Q04673 0.0570177473127842 40.63201461865145 40.0 1.0 no 8103 chrXII_160339 23062 essential YLR005W 290 + TCTTGTGGCTAGCATAGTCG L|98|V L|98|F SSL1 Suppressor of Stem-Loop mutation 461.0 0 0 0 0 0.3846353541359468 Q04673 0.6490041613578796 0.5764661431312561 51.852064646998656 50.0 1.0 no 8104 chrXII_160498r 23063 essential YLR005W 452 - GGACAAAATCTATGGCGTAC V|157|L V|157|I SSL1 Suppressor of Stem-Loop mutation 461.0 0 0 0 0 -0.15537085883819318 Q04673 0.018186954781413082 0.18989364802837366 1.0951199531555176 0.7210599780082703 42.134508603297945 45.0 1.0 no 8105 chrXII_160534 23064 essential YLR005W 485 + CCAAAATCCGATATCTCAAA Q|163|E Q|163|* SSL1 Suppressor of Stem-Loop mutation 461.0 0 0 0 0 0.06629769345954087 Q04673 0.01099260989576578 0.887440025806427 39.421377888015 35.0 1.0 no 8106 chrXII_160534r 23065 essential YLR005W 488 - CCATTTGAGATATCGGATTT M|169|I M|169|I SSL1 Suppressor of Stem-Loop mutation 461.0 0 0 0 0 0.5339360609422633 Q04673 0.2412933111190796 0.2412933111190796 1.5443400144577026 1.5443400144577026 43.197003383743954 35.0 1.0 no 8107 chrXII_160586 23068 essential YLR005W 537 + CAACTGGTCAGCCAAGTTAG L|181|V silent|CTG>TTG|L|181 SSL1 Suppressor of Stem-Loop mutation 461.0 0 0 0 0 0.1395687172427651 Q04673 0.19910626113414764 1.6841200590133667 48.22606560717139 50.0 1.0 no 8108 chrXII_160613r 23070 essential YLR005W 567 - AACGCATCAATGTGATCCTG silent|GCG>GCC|A|195 silent|GCG>GCA|A|195 A|195|P A|195|T SSL1 Suppressor of Stem-Loop mutation 461.0 0 0 0 0 -0.08857828194150241 Q04673 0.12056245654821394 0.2743102312088013 5.221940040588379 2.612260103225708 45.4134438178715 45.0 1.0 no 8109 chrXII_160669 23071 essential YLR005W 620 + CCCTTCATTGCAAAATGCAT P|208|R P|208|L P|208|A P|208|S SSL1 Suppressor of Stem-Loop mutation 461.0 0 0 0 0 0.5577762683442982 Q04673 0.01646830141544342 0.07158603519201279 0.3085895478725433 0.07900205254554749 5.579539775848389 5.89031982421875 1.04993999004364 2.511080026626587 46.682480765120886 40.0 1.0 no 8110 chrXII_160641r 23073 essential YLR005W 595 - TTTCGGTTCTTGTTTCCTGA silent|CCG>CCC|P|204 silent|CCG>CCA|P|204 SSL1 Suppressor of Stem-Loop mutation 461.0 0 0 0 0 0.08664163984175441 Q04673 51.46287921852024 40.0 1.0 no 8111 chrXII_160670r 23074 essential YLR005W 624 - TCCAATGCATTTTGCAATGA L|214|F silent|TTG>TTA|L|214 E|215|Q E|215|K SSL1 Suppressor of Stem-Loop mutation 461.0 0 0 0 0 0.8118276113052033 Q04673 0.009329252876341343 0.01113456767052412 0.010190346278250216 3.27866005897522 0.7339599728584291 0.9305599927902222 44.233691255004494 35.0 1.0 no 8112 chrXII_160721r 23076 essential YLR005W 675 - ACTTCCCTTGTACAATGCGC V|232|L V|232|I E|231|Q E|231|K SSL1 Suppressor of Stem-Loop mutation 461.0 0 0 0 0 0.4300947621883863 Q04673 0.025911491364240646 0.5149204730987549 0.0 0.0 0.7163000106811523 -0.24512000381946564 3.662739992141724 6.522140026092528 52.884865229895134 50.0 1.0 no 8113 chrXII_160813 23078 essential YLR005W 764 + TTCTGAGAAAATTAGAGTGA S|256|C S|256|F SSL1 Suppressor of Stem-Loop mutation 461.0 0 0 0 0 -0.6304742835219138 Q04673 0.03618448600172997 0.034664690494537354 0.2078000009059906 -0.32603999972343445 35.049029421452076 30.0 1.0 no 8114 chrXII_160921 23079 essential YLR005W 872 + ACTCGATGAAACTCACTTAA silent|CTC>CTG|L|292 silent|CTC>CTT|L|292 L|292|V L|292|F SSL1 Suppressor of Stem-Loop mutation 461.0 0 0 0 0 0.13906949022480306 Q04673 0.19429323077201846 0.024341350421309468 0.7868800163269043 -0.18474000692367554 38.56168775798358 35.0 1.0 no 8115 chrXII_164422r 23081 essential YLR007W 33 - GCTGTAGCATCCCCTGTTAC A|18|P A|18|T NSE1 Non-SMC Element 336.0 0 0 0 0 -0.3007132213920309 Q07913 0.05322084203362465 0.041646741330623634 59.22798198725474 55.00000000000001 1.0 no 8116 chrXII_164510r 23082 essential YLR007W 121 - ATCGGTTTCCAATCTCATTA D|47|H D|47|N NSE1 Non-SMC Element 336.0 0 0 0 0 0.8958449476807302 Q07913 0.04173277318477631 0.18523336946964264 46.30246505197607 35.0 1.0 no 8117 chrXII_164511r 23083 essential YLR007W 122 - CATCGGTTTCCAATCTCATT D|47|H D|47|N NSE1 Non-SMC Element 336.0 0 0 0 0 0.06479434012467425 Q07913 0.04173277318477631 0.18523336946964264 48.13613424140698 40.0 1.0 no 8118 chrXII_164534 23084 essential YLR007W 142 + CTTCAACGCTTAACACTGAA S|49|* S|49|L T|50|R T|50|M NSE1 Non-SMC Element 336.0 0 0 0 0 -0.6352581085822169 Q07913 0.3733277022838593 0.3354547023773193 0.08639984577894211 41.41570520180443 40.0 1.0 no 8119 chrXII_164605 23086 essential YLR007W 213 + AACGTAAAACTGAACCTTTT N|72|K silent|AAC>AAT|N|72 NSE1 Non-SMC Element 336.0 0 0 0 0 -0.12240646514861375 Q07913 0.0 36.779030357968956 30.0 1.0 no 8120 chrXII_164649r 23087 essential YLR007W 260 - CTGCGTTTCTACCAATCCCG A|93|P A|93|T NSE1 Non-SMC Element 336.0 0 0 0 0 -0.26304273435455555 Q07913 0.3080229163169861 0.7018149495124817 54.2634339946398 55.00000000000001 1.0 no 8121 chrXII_164705 23088 essential YLR007W 313 + TCGAAGATAATACAGCAATA F|105|L silent|TTC>TTT|F|105 NSE1 Non-SMC Element 336.0 0 0 0 0 -0.29673418738648305 Q07913 35.277208280108994 30.0 1.0 no 8122 chrXII_164770r 23090 essential YLR007W 381 - ACGAAAAACCTGTTACTCTC V|134|L V|134|I NSE1 Non-SMC Element 336.0 0 0 0 0 1.0915246195224353 Q07913 0.0 0.0 40.75679265197789 40.0 1.0 no 8123 chrXII_164844r 23091 essential YLR007W 455 - TCATAAACTCGATCTCGTTT M|158|I M|158|I NSE1 Non-SMC Element 336.0 0 0 0 0 -0.04280585315589512 Q07913 1.0 1.0 41.78105933325793 35.0 1.0 no 8124 chrXII_164831r 23093 essential YLR007W 442 - CTCGTTTTGGTTAAACCTTG E|154|Q E|154|K NSE1 Non-SMC Element 336.0 0 0 0 0 0.6424930209139421 Q07913 0.0 0.0 44.51208802703081 40.0 1.0 no 8125 chrXII_164930r 23095 essential YLR007W 541 - GACTTCCTTCACAATTATCG V|187|L V|187|I E|186|Q E|186|K NSE1 Non-SMC Element 336.0 0 0 0 0 -0.025637234071161686 Q07913 0.07921425253152847 0.7403168678283691 0.07890809327363968 0.08038469403982162 44.325680062896936 40.0 1.0 no 8126 chrXII_165087r 23097 essential YLR007W 698 - ACCATTTCAGTTCGCATAAT W|239|S W|239|* W|239|C W|239|* NSE1 Non-SMC Element 336.0 0 0 0 0 -2.3729988162797864 Q07913 0.0 0.0 45.56227686554894 35.0 1.0 yes 8127 chrXII_165095 23098 essential YLR007W 703 + GCGAACTGAAATGGTTTTAC C|235|W silent|TGC>TGT|C|235 L|237|V silent|CTG>TTG|L|237 NSE1 Non-SMC Element 336.0 0 0 0 0 -0.010358529918263665 Q07913 0.0 0.4854508638381958 40.146561955804884 40.0 1.0 no 8128 chrXII_165747 23099 essential YLR008C 317 - CCTCTTTAGAATTCATTTTC E|112|Q E|112|K E|112|D silent|GAG>GAA|E|112 PAM18 Presequence translocase-Associated Motor 168.0 0 0 0 0 -0.2018168072711145 Q07914 0.956179976463318 0.9475290179252625 0.94931298494339 0.0 0.0 0.0 -1.0537799596786501 -0.7358499765396118 1.591838002204895 41.616485424868934 30.0 0.0 no 8129 chrXII_165809r 23100 essential YLR008C 252 + TCAATATCGAAGGGACTTAA S|85|* S|85|L PAM18 Presequence translocase-Associated Motor 168.0 0 0 0 0 -2.2885304020509443 Q07914 0.9298099875450134 0.14601708948612213 38.316739746055134 35.0 0.0 yes 8130 chrXII_165776r 23102 essential YLR008C 285 + ACTACTGCCTTCTTGAAAGG T|96|S T|96|I T|97|S T|97|I PAM18 Presequence translocase-Associated Motor 168.0 0 0 0 0 0.11239790635107497 Q07914 0.9491789937019348 0.9472420215606691 0.9491789937019348 0.9472420215606691 0.9109357595443726 0.4502260684967041 0.7400200963020325 0.14416338503360748 46.42282300230682 45.0 0.0 no 8131 chrXII_165818r 23103 essential YLR008C 243 + GCATATAAATCAATATCGAA A|82|G A|82|V PAM18 Presequence translocase-Associated Motor 168.0 0 0 0 0 0.4763002271554333 Q07914 0.9484469890594482 0.9504740238189696 0.35297688841819763 0.5474329590797424 33.41295347107638 25.0 0.0 no 8132 chrXII_165899r 23106 essential YLR008C 162 + GATCAAGCTTTGAACTACAT Q|56|E Q|56|* PAM18 Presequence translocase-Associated Motor 168.0 0 0 0 0 -0.47337384631242996 Q07914 0.9590039849281312 0.4700393974781037 40.481781479952815 35.0 0.0 no 8133 chrXII_165909 23107 essential YLR008C 155 - TCAAAGCTTGATCAAAATAA L|58|F silent|TTG>TTA|L|58 A|57|P A|57|T PAM18 Presequence translocase-Associated Motor 168.0 0 0 0 0 1.3133651069590089 Q07914 0.9587849974632264 0.9573720097541808 0.9523990154266356 0.4045567810535431 0.10152088105678557 0.4572188556194306 32.47181434117181 25.0 0.0 no 8134 chrXII_166022 23114 essential YLR008C 42 - TGACCAGGAATGGGTAGTTG G|20|A G|20|D G|20|R G|20|S PAM18 Presequence translocase-Associated Motor 168.0 0 0 0 0 -1.4047723692818377 Q07914 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 47.795656759731905 50.0 0.0 no 8135 chrXII_166025r 23115 essential YLR008C 36 + GCACCACAACTACCCATTCC P|14|A P|14|S A|13|G A|13|V PAM18 Presequence translocase-Associated Motor 168.0 0 0 0 0 -0.5370767546179781 Q07914 0.9562489986419678 0.9498909711837769 0.9484469890594482 0.9504740238189696 0.06121060252189636 0.04032550752162933 0.013709630817174913 1.0 55.43687586752935 55.00000000000001 0.0 no 8136 chrXII_166561 23116 essential YLR009W 24 + TGCTCATCCCCATGTTATCC C|9|W silent|TGC>TGT|C|9 S|10|* S|10|L RLP24 Ribosomal-Like Protein 199.0 0 0 0 0 0.8302829670273351 Q07915 0.0 0.006317670457065106 57.88279883653985 50.0 1.0 no 8137 chrXII_166579r 23118 essential YLR009W 45 - ACAAACATGATCCCATGACC V|22|L V|22|M M|20|I M|20|I RLP24 Ribosomal-Like Protein 199.0 0 0 0 0 -0.5652113687297723 Q07915 0.0 0.0 0.4794765412807465 0.4794765412807465 46.20047052478179 45.0 1.0 no 8138 chrXII_166629 23119 essential YLR009W 92 + CTGCCGTTCTAAGTGTCACA C|32|W silent|TGC>TGT|C|32 R|33|G R|33|C RLP24 Ribosomal-Like Protein 199.0 0 1 0 0 -1.1971267470492142 Q07915 0.0 0.008752269670367241 0.0014023015974089505 52.57725091499367 50.0 1.0 no 8139 chrXII_166691r 23121 essential YLR009W 157 - GGCAGCCTTTCTGAAAGCTT A|59|P A|59|T A|58|P A|58|T RLP24 Ribosomal-Like Protein 199.0 0 1 0 0 -0.4338247284289831 Q07915 0.24531735479831696 0.6308714151382446 0.07066082954406737 0.3360687792301178 53.27288683867715 50.0 1.0 no 8140 chrXII_166752r 23122 essential YLR009W 218 - TAACAGGGACATTTCTTCTT V|79|L V|79|I RLP24 Ribosomal-Like Protein 199.0 0 0 0 0 0.5512450282382124 Q07915 0.07771354913711548 0.13338571786880493 43.34873373420714 35.0 1.0 no 8141 chrXII_166767r 23124 essential YLR009W 233 - ACTCTCTATTGTATCTAACA E|84|Q E|84|K E|84|D silent|GAG>GAA|E|84 RLP24 Ribosomal-Like Protein 199.0 0 1 0 0 0.6567009495672695 Q07915 0.09588991105556488 0.09159017354249954 0.7938754558563232 41.06141676117125 30.0 1.0 no 8142 chrXII_166768r 23125 essential YLR009W 234 - AACTCTCTATTGTATCTAAC E|84|D silent|GAG>GAA|E|84 E|84|Q E|84|K RLP24 Ribosomal-Like Protein 199.0 0 1 0 0 -0.3326996766657587 Q07915 0.7938754558563232 0.09588991105556488 0.09159017354249954 38.17164192659402 30.0 1.0 no 8143 chrXII_166853r 23126 essential YLR009W 319 - TCTCATTCTATTCTTGTAGA M|112|I M|112|I R|113|T R|113|K RLP24 Ribosomal-Like Protein 199.0 0 0 0 0 0.3376823544346401 Q07915 0.07756873220205307 0.07756873220205307 0.4091834425926209 1.0 43.24956801793894 30.0 1.0 no 8144 chrXII_167421 23128 essential YLR010C 362 - TTTCAAAAATTGGCGGACTT E|127|Q E|127|K 0 0 0 0 -0.4758510676545808 Q07921 0.956179976463318 0.9475290179252625 0.0 0.0 40.111091163680726 35.0 0.0 no 8145 chrXII_167493 23130 essential YLR010C 290 - TCAATCTCAAATCATCTTTA L|103|F silent|TTG>TTA|L|103 R|102|T R|102|K 0 0 0 0 0.6810114491765751 Q07921 0.9587849974632264 0.932735025882721 0.955805003643036 0.04519471526145935 0.7172288298606873 1.0 37.110621670658304 25.0 0.0 no 8146 chrXII_167669 23132 essential YLR010C 114 - ACAATCCTGAATCTTTTGGA V|45|L V|45|I R|43|S silent|AGG>AGA|R|43 0 0 0 0 -1.9922649253111449 Q07921 0.9539830088615416 0.9574310183525084 0.9087679982185364 0.13998927175998688 1.0 0.021798906847834587 43.01804846478837 35.0 0.0 no 8147 chrXII_167714r 23133 essential YLR010C 66 + AACAATGTTTACGGTGGAAA N|23|K silent|AAC>AAT|N|23 0 0 0 0 0.6287556138804555 Q07921 0.9439849853515624 38.24702450421506 35.0 0.0 no 8148 chrXII_167720r 23134 essential YLR010C 60 + ATTCATAACAATGTTTACGG H|22|D H|22|Y 0 0 0 0 0.9432991974591636 Q07921 0.9473130106925964 0.9489949941635132 36.96217649946277 30.0 0.0 no 8149 chrXII_184345 23135 essential YLR022C 562 - ACTAATCTTCTCAATAAGTT S|194|T S|194|N K|192|N silent|AAG>AAA|K|192 SDO1 250.0 0 0 0 0 0.7155445448670812 Q07953 0.9512869715690612 0.9536849856376648 0.9355990290641784 0.5725736021995544 0.4933315515518189 0.09386572986841203 36.70345985973751 25.0 0.0 no 8150 chrXII_184403 23137 essential YLR022C 504 - TTCATCTTCGCCCTTACTAT M|174|I M|174|I K|173|N silent|AAG>AAA|K|173 SDO1 250.0 0 0 0 0 0.06527568442820855 Q07953 0.9553959965705872 0.9553959965705872 0.9355990290641784 0.0 0.0 0.036532949656248086 0.14173999428749084 0.14173999428749084 51.61659048871519 40.0 0.0 no 8151 chrXII_184413r 23138 essential YLR022C 491 + GCAAATTATTCCAATAGTAA Q|165|E Q|165|* SDO1 250.0 0 0 0 0 0.30782019490406964 Q07953 0.9590039849281312 0.7437459230422974 36.23960634669169 25.0 0.0 no 8152 chrXII_184506 23140 essential YLR022C 401 - TCAGTTCCTGTAAAGCTTTG silent|CTG>CTC|L|140 silent|CTG>CTA|L|140 E|139|Q E|139|K SDO1 250.0 0 0 0 0 0.6471068662015138 Q07953 0.956179976463318 0.9475290179252625 0.29369398951530457 0.2196536511182785 46.039293323315114 40.0 0.0 no 8153 chrXII_184655r 23142 essential YLR022C 249 + ATCGAGGAGATCATGCATAA I|84|M silent|ATC>ATT|I|84 SDO1 250.0 0 0 0 0 -0.4997911926003698 Q07953 0.9598389863967896 0.061784688383340836 42.79809363754811 40.0 0.0 no 8154 chrXII_184821r 23144 essential YLR022C 83 + AGTCGCGTGCTACCAAAATA silent|GTC>GTG|V|29 silent|GTC>GTT|V|29 A|30|G A|30|V SDO1 250.0 0 0 0 0 -0.8085264634549334 Q07953 0.9484469890594482 0.9504740238189696 0.0 0.0 1.859760046005249 -0.029999999329447743 46.625184131827844 45.0 0.0 no 8155 chrXII_194516r 23146 high_effect YLR025W 67 - ATGCTCCCTCAACCGCACTA E|28|D silent|GAG>GAA|E|28 E|28|Q E|28|K SNF7 Sucrose NonFermenting 240.0 0 0 0 0 -1.5899305465644231 P39929 0.94931298494339 0.956179976463318 0.9475290179252625 0.5351752638816833 0.2881382703781128 0.3906385600566864 0.4218200147151947 -0.2295800000429153 0.1085200011730194 57.24526366579755 55.00000000000001 1.0 no 8156 chrXII_194552r 23147 high_effect YLR025W 103 - ACGTAAATGCGATTGCTTTT R|41|P R|41|H SNF7 Sucrose NonFermenting 240.0 0 0 0 0 0.2572936566010893 P39929 0.9099509716033936 0.9570810198783876 0.0587381012737751 0.038864366710186005 3.4171199798583984 0.6872000098228455 42.589249260633885 35.0 1.0 no 8157 chrXII_194602 23148 high_effect YLR025W 150 + GCTAGAATCTTTTTGACGAA A|51|G A|51|V SNF7 Sucrose NonFermenting 240.0 0 0 0 0 -0.5951358345179398 P39929 0.9484469890594482 0.9504740238189696 0.039589203894138336 0.2414519190788269 2.034600019454956 0.9048200249671936 40.468999640970075 35.0 1.0 no 8158 chrXII_194601 23149 high_effect YLR025W 149 + AGCTAGAATCTTTTTGACGA A|51|G A|51|V SNF7 Sucrose NonFermenting 240.0 0 0 0 0 -0.14806820891548444 P39929 0.9484469890594482 0.9504740238189696 0.039589203894138336 0.2414519190788269 2.034600019454956 0.9048200249671936 41.90760787506804 35.0 1.0 no 8159 chrXII_194667 23150 high_effect YLR025W 215 + AATCGAACAACTTTTAAGTA I|73|M silent|ATC>ATT|I|73 SNF7 Sucrose NonFermenting 240.0 0 1 0 0 1.3267041293139608 P39929 0.9598389863967896 0.2671982049942017 1.3113399744033811 33.788842521043485 25.0 1.0 no 8160 chrXII_194674 23151 high_effect YLR025W 222 + CAACTTTTAAGTAAGGTAGA L|76|V L|76|F SNF7 Sucrose NonFermenting 240.0 0 1 0 0 0.3624030029906132 P39929 0.9512209892272948 0.9587849974632264 0.2630293369293213 0.0536990649998188 1.341339945793152 0.4596000015735626 36.202508685865325 30.0 1.0 no 8161 chrXII_194811r 23156 high_effect YLR025W 362 - CATCCACTTTATCTATGTCA D|127|H D|127|N silent|GTG>GTC|V|126 silent|GTG>GTA|V|126 SNF7 Sucrose NonFermenting 240.0 0 0 0 0 0.8400031451895065 P39929 0.9486550092697144 0.956179976463318 0.009536203928291798 0.02510673925280571 1.0281599760055542 0.3837800025939941 46.02643195166854 35.0 1.0 no 8162 chrXII_194899r 23158 high_effect YLR025W 450 - TCGTTTGCCCCAGTAATTAA E|157|Q E|157|K SNF7 Sucrose NonFermenting 240.0 0 0 0 0 0.11377042762083142 P39929 0.956179976463318 0.9475290179252625 0.5322223901748657 0.7429038882255554 49.356448407850564 40.0 1.0 no 8163 chrXII_194990r 23161 high_effect YLR025W 541 - AACATTATTATTAACGATCT V|187|L V|187|I SNF7 Sucrose NonFermenting 240.0 0 0 0 0 0.4614479537902113 P39929 0.9539830088615416 0.9574310183525084 0.40434688329696655 0.4925504326820374 33.491945643471524 20.0 1.0 no 8164 chrXII_195749r 23165 essential YLR026C 701 + CGACTCTCAACTAATGTTAA D|235|E silent|GAC>GAT|D|235 S|236|C S|236|F SED5 Suppressor of Erd2 Deletion 340.0 0 0 0 0 -0.2682218083186793 Q01590 0.8519978523254395 0.02222263440489769 0.01728195510804653 38.75691702042582 35.0 0.0 no 8165 chrXII_196047 23170 essential YLR026C 406 - GACATTTTTGGAGTGCTGTA V|142|L V|142|I SED5 Suppressor of Erd2 Deletion 340.0 0 0 0 0 -0.6736776800876055 Q01590 0.02529214322566986 0.1215248554944992 46.99753305050314 40.0 0.0 no 8166 chrXII_196137 23172 essential YLR026C 316 - TTGCACTAAACTTTGTTCGA silent|GTG>GTC|V|111 silent|GTG>GTA|V|111 V|111|L V|111|M SED5 Suppressor of Erd2 Deletion 340.0 0 0 0 0 0.4255156832155019 Q01590 0.21756304800510406 0.07677750289440155 42.19834079134358 35.0 0.0 no 8167 chrXII_196329r 23175 essential YLR026C 121 + CCAACAACACAACCGGCAAT silent|GCC>GCG|A|41 silent|GCC>GCT|A|41 N|42|K silent|AAC>AAT|N|42 SED5 Suppressor of Erd2 Deletion 340.0 0 0 0 1 0.7674367768122334 Q01590 0.931059718132019 46.139477215075324 50.0 0.0 no 8168 chrXII_196330r 23176 essential YLR026C 120 + GCCAACAACACAACCGGCAA silent|GCC>GCG|A|41 silent|GCC>GCT|A|41 A|41|G A|41|V SED5 Suppressor of Erd2 Deletion 340.0 0 0 0 1 0.11843367448404656 Q01590 0.4307320713996887 0.2728671133518219 49.241008744819176 55.00000000000001 0.0 no 8169 chrXII_202088r 23179 essential YLR029C 420 + GCTAGAGGTTTGACTGCCAC invalid seq invalid seq invalid seq invalid seq RPL15A Ribosomal Protein of the Large subunit 204.0 0 0 0 0 -0.07315223159951079 P05748 54.07090823151565 55.00000000000001 0.0 no 8170 chrXII_202072 23180 essential YLR029C 439 - ACCTCTGGATTTCTTACCAG invalid seq invalid seq invalid seq invalid seq RPL15A Ribosomal Protein of the Large subunit 204.0 0 0 0 0 -0.6755093272963529 P05748 50.55334827872332 45.0 0.0 no 8171 chrXII_208831r 23184 essential YLR033W 73 - TACTACATGACATTTCACAG V|31|L V|31|I V|30|L V|30|I RSC58 Remodel the Structure of Chromatin 502.0 0 0 0 0 -6.738106999999938 Q07979 1.0 0.7757988572120667 0.04369354248046875 0.06359374523162843 39.70623156209831 35.0 1.0 yes 8172 chrXII_209042 23185 essential YLR033W 281 + GCTGTATCACGACATTAAGC L|95|V silent|CTG>TTG|L|95 RSC58 Remodel the Structure of Chromatin 502.0 0 0 0 0 -0.0023043876855484147 Q07979 0.029137570410966877 45.48984610061235 45.0 1.0 no 8173 chrXII_209075 23186 essential YLR033W 314 + CCTCATTCACTTTTATCCTC silent|CTC>CTG|L|106 silent|CTC>CTT|L|106 L|106|V L|106|F RSC58 Remodel the Structure of Chromatin 502.0 0 0 0 0 -1.4575424603631484 Q07979 0.0 0.0 50.104146715919974 40.0 1.0 no 8174 chrXII_209076 23188 essential YLR033W 315 + CTCATTCACTTTTATCCTCA silent|CTC>CTG|L|106 silent|CTC>CTT|L|106 H|108|D H|108|Y RSC58 Remodel the Structure of Chromatin 502.0 0 0 0 0 0.1272556105023328 Q07979 0.18566255271434784 0.27507922053337097 47.47656132864523 35.0 1.0 no 8175 chrXII_209154 23189 essential YLR033W 393 + TTACGAGAATGTTGTAGGAT R|133|G R|133|* RSC58 Remodel the Structure of Chromatin 502.0 0 0 0 0 -0.9683089388073702 Q07979 0.0 40.00606925070457 35.0 1.0 no 8176 chrXII_209541r 23195 essential YLR033W 783 - AATCTAGTCATCATTTCAGT R|267|T R|267|K RSC58 Remodel the Structure of Chromatin 502.0 0 0 0 0 0.2777663733312136 Q07979 0.10352042317390442 0.6258112788200378 42.31786491424475 30.0 1.0 no 8177 chrXII_209581 23196 essential YLR033W 820 + ATGCTTTACCTACAACCGTC A|275|G A|275|V RSC58 Remodel the Structure of Chromatin 502.0 0 0 0 0 0.6245918327404683 Q07979 0.3996197283267975 0.26663738489151 49.270044093786794 45.0 1.0 no 8178 chrXII_209826 23202 essential YLR033W 1065 + AGCAATGGCGTTCAGGACGA S|356|R silent|AGC>AGT|S|356 RSC58 Remodel the Structure of Chromatin 502.0 0 0 0 0 0.5729726458488796 Q07979 0.5563976168632507 51.30826790809817 55.00000000000001 1.0 no 8179 chrXII_235774 23203 essential YLR045C 1910 - CCAAAGACTTAGACGTCAAC L|643|F silent|TTG>TTA|L|643 STU2 Suppressor of TUbulin 888.0 0 0 0 0 0.5679828104762671 P46675 0.9587849974632264 0.07349298149347305 41.5275646261191 45.0 0.0 no 8180 chrXII_235774r 23204 essential YLR045C 1907 + CCTGTTGACGTCTAAGTCTT L|637|V silent|CTG>TTG|L|637 STU2 Suppressor of TUbulin 888.0 0 0 0 0 1.2134450921799549 P46675 0.9512209892272948 0.4130918383598328 49.590780946078326 45.0 0.0 no 8181 chrXII_235798r 23205 essential YLR045C 1883 + AGCTGCTAACAATAAATCGA A|629|G A|629|V A|630|G A|630|V STU2 Suppressor of TUbulin 888.0 0 1 0 0 0.1479839662442478 P46675 0.9484469890594482 0.9504740238189696 0.9484469890594482 0.9504740238189696 0.3906048834323883 0.2966155409812927 38.80179812915037 35.0 0.0 no 8182 chrXII_235973 23208 essential YLR045C 1711 - ATTCGTTTCAATAGTGCTAT silent|ACG>ACC|T|576 silent|ACG>ACA|T|576 STU2 Suppressor of TUbulin 888.0 0 0 0 0 0.30301042110591103 P46675 42.39179813484162 30.0 0.0 no 8183 chrXII_236001r 23209 essential YLR045C 1680 + CCTAATTTCAGTATTGCAAG P|561|R P|561|L STU2 Suppressor of TUbulin 888.0 0 0 0 0 1.3776595512597851 P46675 0.9432820081710817 0.9430609941482544 0.030543697997927662 0.021977154538035396 41.44951766365699 35.0 0.0 no 8184 chrXII_236136 23210 essential YLR045C 1548 - AATCCAATAGTTCTTATAGC G|522|A G|522|E G|522|R G|522|R STU2 Suppressor of TUbulin 888.0 0 0 0 0 -0.9227627832702524 P46675 0.9499930143356324 0.9438679814338684 0.941340982913971 0.941340982913971 0.0 0.0 0.0 0.0 4.187540054321288 21.36322021484375 35.149620056152344 35.149620056152344 40.1870869117343 30.0 0.0 no 8185 chrXII_236200 23211 essential YLR045C 1484 - CATCCTTCAAGTATCTTTGC D|501|H D|501|N K|500|N silent|AAG>AAA|K|500 STU2 Suppressor of TUbulin 888.0 0 0 0 0 -0.06219027537294295 P46675 0.9486550092697144 0.956179976463318 0.9355990290641784 0.08745183795690536 0.2891687154769897 0.5097637176513672 0.2842400074005127 -0.08157999813556671 2.181619882583618 47.341255285005104 40.0 0.0 no 8186 chrXII_236333 23212 essential YLR045C 1351 - ATCTTCATTGCGTCCACTGG D|457|H D|457|N E|456|Q E|456|K STU2 Suppressor of TUbulin 888.0 0 0 0 0 0.6313456951373593 P46675 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.03123850002884865 0.1429249793291092 0.04144013300538063 0.033023674041032784 2.7293200492858887 1.8637200593948364 0.1264200061559677 1.0234600305557249 53.145993138168194 50.0 0.0 no 8187 chrXII_236396r 23214 essential YLR045C 1285 + CTTCTGTGATAGAGGCCATT S|430|C S|430|F STU2 Suppressor of TUbulin 888.0 0 0 0 0 -0.12840037777139846 P46675 0.945252001285553 0.9294660091400146 0.005430919118225575 0.0028924650978296995 -0.3072800040245056 -0.7914400100708008 50.315866337795114 45.0 0.0 no 8188 chrXII_236346r 23215 essential YLR045C 1335 + TACGATCCATTAGCCTCCAG Y|446|* silent|TAC>TAT|Y|446 P|448|A P|448|S STU2 Suppressor of TUbulin 888.0 0 0 0 0 -1.4880647468237838 P46675 0.9562489986419678 0.9498909711837769 0.08227881789207457 0.10495973378419876 2.765360116958618 4.56850004196167 52.67067317562054 50.0 0.0 no 8189 chrXII_236435r 23216 essential YLR045C 1246 + TCTTCACTCCCTTGTTAGAC silent|GTC>GTG|V|416 silent|GTC>GTT|V|416 F|417|L silent|TTC>TTT|F|417 STU2 Suppressor of TUbulin 888.0 0 0 0 0 0.3927952026784319 P46675 0.9387490153312684 0.4578650891780853 2.0733799934387207 52.00919266317636 45.0 0.0 no 8190 chrXII_236456 23219 essential YLR045C 1228 - GACTAGTGAAACATAATCCT V|416|L V|416|I STU2 Suppressor of TUbulin 888.0 0 0 0 0 -0.820777757486611 P46675 0.9539830088615416 0.9574310183525084 0.11688149720430376 0.18081749975681305 0.2441000044345856 -0.19594000279903406 39.45293302911534 35.0 0.0 no 8191 chrXII_236551 23220 essential YLR045C 1133 - TTGCATCTTTCTGGATAATA A|384|P A|384|T D|383|H D|383|N STU2 Suppressor of TUbulin 888.0 0 0 0 0 0.5664939946845939 P46675 0.9573720097541808 0.9523990154266356 0.9486550092697144 0.956179976463318 0.15221886336803436 0.03931572288274765 0.0 0.0 -1.2250800132751465 0.09679999947547913 3.3203799724578857 2.4558000564575195 -1.0454399585723877 0.3950000107288361 41.47631625123114 30.0 0.0 no 8192 chrXII_236713r 23224 essential YLR045C 968 + GATCCTCGATAAACTGCCTA I|324|M silent|ATC>ATT|I|324 L|325|V L|325|F STU2 Suppressor of TUbulin 888.0 0 0 0 0 -0.5313243782758702 P46675 0.9598389863967896 0.9512209892272948 0.9587849974632264 0.010160570032894613 0.056189950555562966 0.030727989971637726 2.2533400058746342 1.3786200284957886 1.0202399492263794 -1.6003799438476562 1.2924400568008425 1.2653900384902954 47.688213568196545 45.0 0.0 no 8193 chrXII_236772 23225 essential YLR045C 912 - ACTCCACTTTGCTGTTTTGA G|310|A G|310|E V|311|L V|311|I STU2 Suppressor of TUbulin 888.0 0 0 0 0 0.4141973515293222 P46675 0.9499930143356324 0.9438679814338684 0.9539830088615416 0.9574310183525084 0.7781305313110352 1.0 0.4094611704349518 0.2766057848930359 50.6291426485472 40.0 0.0 no 8194 chrXII_236775 23226 essential YLR045C 909 - CCACTTTGCTGTTTTGATGG S|309|T S|309|N G|310|R G|310|R STU2 Suppressor of TUbulin 888.0 0 0 0 0 0.08945732278638031 P46675 0.9512869715690612 0.9536849856376648 0.941340982913971 0.941340982913971 0.6087751388549805 0.8416181206703186 0.550250232219696 0.550250232219696 49.581506333131024 45.0 0.0 no 8195 chrXII_237061r 23233 essential YLR045C 620 + TGTCGAGATCTATAAGGTTA silent|GTC>GTG|V|208 silent|GTC>GTT|V|208 STU2 Suppressor of TUbulin 888.0 0 0 0 0 0.8634188938653862 P46675 41.196439228615475 35.0 0.0 no 8196 chrXII_237107 23234 essential YLR045C 577 - AACGTTTCTATCACCATGAC V|199|L V|199|I STU2 Suppressor of TUbulin 888.0 0 0 0 0 -0.7192497509256404 P46675 0.9539830088615416 0.9574310183525084 0.056567758321762085 0.40926358103752136 1.6173399686813354 -0.7591400146484375 44.23185084021475 40.0 0.0 no 8197 chrXII_237117 23235 essential YLR045C 567 - TCACCATGACCGGCTAGTTG G|195|A G|195|D D|196|H D|196|N STU2 Suppressor of TUbulin 888.0 0 0 0 0 0.3355192009435549 P46675 0.9499930143356324 0.9446240067481996 0.9486550092697144 0.956179976463318 1.0 0.010921177454292774 0.0 0.0 -0.2635999917984009 -0.0350399985909462 1.6730999946594238 1.4043400287628174 53.70793780889096 55.00000000000001 0.0 no 8198 chrXII_237203 23238 essential YLR045C 481 - CATCAACTCATAAACACAAT L|166|F silent|TTG>TTA|L|166 E|165|D silent|GAG>GAA|E|165 STU2 Suppressor of TUbulin 888.0 0 0 0 0 0.7058519283498272 P46675 0.9587849974632264 0.94931298494339 0.04362888634204865 0.4271426200866699 0.8272600173950195 1.04066002368927 35.18672362112943 30.0 0.0 no 8199 chrXII_237229r 23239 essential YLR045C 452 + ACTGCCAAAATTAATTGCTG L|152|V silent|CTG>TTG|L|152 P|153|A P|153|S STU2 Suppressor of TUbulin 888.0 0 0 0 0 -0.4820095195920357 P46675 0.9512209892272948 0.9562489986419678 0.9498909711837769 0.2846343219280243 0.0 0.0 1.2706199884414673 2.2750799655914307 3.006880044937134 40.10255547256918 35.0 0.0 no 8200 chrXII_237280r 23241 essential YLR045C 401 + TACATCTATTACGCAATCGG T|135|R T|135|I S|136|C S|136|F STU2 Suppressor of TUbulin 888.0 0 0 0 0 -0.2556428362199432 P46675 0.9476869702339172 0.9472420215606691 0.945252001285553 0.9294660091400146 0.5619409084320068 0.22268089652061465 0.0 0.0 -1.598960041999817 -0.5103999972343445 0.9987999796867372 3.454859972000122 42.27985348183881 40.0 0.0 no 8201 chrXII_237309r 23242 essential YLR045C 372 + AGCTGTATACTCTCACTATG S|125|R silent|AGC>AGT|S|125 STU2 Suppressor of TUbulin 888.0 0 0 0 0 0.9971163824997942 P46675 0.9417110085487366 0.16289375722408295 -0.8408600091934204 45.28852216782508 40.0 0.0 no 8202 chrXII_237369 23243 essential YLR045C 315 - AAGCCCTTTTCCACAAGCAA G|111|A G|111|D G|111|R G|111|S STU2 Suppressor of TUbulin 888.0 0 0 0 0 -0.07243240695031505 P46675 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.27629464864730835 0.05604530498385429 0.02755056880414486 0.1513337343931198 2.5990800857543945 7.31171989440918 13.824819564819336 3.8577799797058105 51.07310933757384 45.0 0.0 no 8203 chrXII_237373r 23244 essential YLR045C 308 + GACACCATTGCTTGTGGAAA T|104|R T|104|I P|105|A P|105|S STU2 Suppressor of TUbulin 888.0 0 0 0 0 0.5914593255003143 P46675 0.9476869702339172 0.9472420215606691 0.9562489986419678 0.9498909711837769 0.0104459123685956 1.0 0.0 0.0 2.480839967727661 -1.5765000581741333 2.9212000370025635 3.6792600154876713 46.74975112649838 45.0 0.0 no 8204 chrXII_237428 23246 essential YLR045C 256 - TTTCAAAGACGATGACGCAA L|91|F silent|TTG>TTA|L|91 STU2 Suppressor of TUbulin 888.0 0 0 0 0 1.2339355598981232 P46675 0.9587849974632264 0.25432270765304565 -0.3006600141525269 40.083780851650936 40.0 0.0 no 8205 chrXII_237538r 23247 essential YLR045C 143 + CAACATACAAATTTACTGGA N|49|K silent|AAC>AAT|N|49 STU2 Suppressor of TUbulin 888.0 0 0 0 0 0.3817594927182951 P46675 0.9439849853515624 35.567384696060685 30.0 0.0 no 8206 chrXII_237579r 23249 essential YLR045C 102 + CAGCTTTTTAGAAACTCCGT L|36|V L|36|F STU2 Suppressor of TUbulin 888.0 0 0 0 0 -0.7316755606759172 P46675 0.9512209892272948 0.9587849974632264 1.0 0.1918237507343292 1.1704599857330322 0.40446001291275024 45.599548437566796 40.0 0.0 no 8207 chrXII_237644 23251 essential YLR045C 40 - GTACGTTAATCGCTCTTCTA silent|ACG>ACC|T|19 silent|ACG>ACA|T|19 STU2 Suppressor of TUbulin 888.0 0 0 0 0 -0.21792522887604326 P46675 46.60061187808356 40.0 0.0 no 8208 chrXII_237645 23252 essential YLR045C 39 - TACGTTAATCGCTCTTCTAG silent|ACG>ACC|T|19 silent|ACG>ACA|T|19 STU2 Suppressor of TUbulin 888.0 0 0 0 0 -0.2202426179706961 P46675 44.12089594309253 40.0 0.0 no 8209 chrXII_236271 23253 essential YLR045C 1413 - GTACACTCCATTCTGATTTG C|477|S C|477|Y E|476|D silent|GAG>GAA|E|476 STU2 Suppressor of TUbulin 888.0 0 0 0 0 -1.7923395150686243 P46675 0.9421560168266296 0.9290120005607604 0.94931298494339 0.9879643321037292 0.04234070330858231 0.0 1.5240199565887451 27.025480270385746 1.5084799528121948 46.195233785604216 40.0 0.0 no 8210 chrXII_246504 23255 essential YLR051C 454 - CTCACTCTTGTCTTCAATTA E|158|Q E|158|K S|157|T S|157|N FCF2 Faf1p Copurifying Factor 217.0 0 1 0 0 0.3789898392167475 Q12035 0.07915288209915161 0.07977822422981262 1.0 0.1234997659921646 44.741613835765975 35.0 0.0 no 8211 chrXII_246526 23256 essential YLR051C 432 - GTACCAATAGCAAACCTCTC G|150|A G|150|D G|150|R G|150|S FCF2 Faf1p Copurifying Factor 217.0 0 0 0 0 -0.6943910457534671 Q12035 0.0 0.0 0.0 0.0 46.528627669630175 45.0 0.0 no 8212 chrXII_246562 23259 essential YLR051C 396 - TGCTTCTTATAATGTCTCTT K|138|N silent|AAG>AAA|K|138 K|137|N silent|AAG>AAA|K|137 FCF2 Faf1p Copurifying Factor 217.0 0 0 0 0 0.49140879289006 Q12035 0.011998053640127182 0.011972297914326193 43.703657405089466 30.0 0.0 no 8213 chrXII_246637 23261 essential YLR051C 321 - CGCATGTTATCATCTGGCTT M|113|I M|113|I FCF2 Faf1p Copurifying Factor 217.0 0 0 0 0 -0.7570847063815069 Q12035 0.30711784958839417 0.30711784958839417 50.971096100838004 45.0 0.0 no 8214 chrXII_246875r 23266 essential YLR051C 80 + ACAAGTTTCTCTTCAACAAG Q|28|E Q|28|* FCF2 Faf1p Copurifying Factor 217.0 0 0 0 0 0.08980368333816696 Q12035 1.0 39.458820702926566 35.0 0.0 no 8215 chrXII_253937 23267 high_effect YLR056W 76 + CAGCTAATATTCCTGTCAAG A|27|G A|27|V ERG3 ERGosterol biosynthesis 365.0 0 0 0 0 0.033696241224616896 P32353 0.9484469890594482 0.9504740238189696 0.4497902393341065 0.14484809339046478 43.69437725886649 40.0 1.0 no 8216 chrXII_253989 23269 high_effect YLR056W 128 + CAGCAATTCTACGATTTTGC S|44|R silent|AGC>AGT|S|44 ERG3 ERGosterol biosynthesis 365.0 0 0 0 0 -0.2616829723239133 P32353 0.9417110085487366 0.528586745262146 43.87823283644104 40.0 1.0 no 8217 chrXII_254024r 23271 high_effect YLR056W 166 - ACATTCTTTGACGGCATTCT C|62|S C|62|Y E|61|Q E|61|K ERG3 ERGosterol biosynthesis 365.0 0 0 0 0 0.6214568217702523 P32353 0.9421560168266296 0.9290120005607604 0.956179976463318 0.9475290179252625 0.09196926653385162 0.09023106843233107 0.5081093907356262 0.8602861762046814 47.88098248274547 40.0 1.0 no 8218 chrXII_254259r 23276 high_effect YLR056W 401 - ACTTGATTTCCATTGCCATT K|140|N silent|AAG>AAA|K|140 ERG3 ERGosterol biosynthesis 365.0 0 0 0 0 0.8612411324086542 P32353 0.9355990290641784 0.4674551784992218 48.88757247867028 35.0 1.0 no 8219 chrXII_254299r 23277 high_effect YLR056W 441 - ACGGTCAACATCGACATCCA V|154|L V|154|I L|152|F silent|TTG>TTA|L|152 ERG3 ERGosterol biosynthesis 365.0 0 0 0 0 -0.09774676725062616 P32353 0.9539830088615416 0.9574310183525084 0.9587849974632264 0.4122864902019501 0.23431968688964844 0.02696954645216465 49.304420852787864 50.0 1.0 no 8220 chrXII_254323r 23278 high_effect YLR056W 465 - TTCAATTCCATAACAAACCA L|161|F silent|TTG>TTA|L|161 ERG3 ERGosterol biosynthesis 365.0 0 0 0 0 0.28416298683805763 P32353 0.9587849974632264 0.017765730619430542 39.50121445710869 30.0 1.0 no 8221 chrXII_254422 23279 high_effect YLR056W 561 + TTCATCTTTTTCACTGATTG F|188|L silent|TTC>TTT|F|188 I|189|M silent|ATC>ATT|I|189 ERG3 ERGosterol biosynthesis 365.0 0 0 0 0 0.2789575583545554 P32353 0.9387490153312684 0.9598389863967896 0.0 0.1458900272846222 41.477040328315574 30.0 1.0 no 8222 chrXII_254453 23280 high_effect YLR056W 592 + TAGCGCACAGATGGTTGCAT A|199|G A|199|V H|200|D H|200|Y ERG3 ERGosterol biosynthesis 365.0 0 0 0 0 -0.06845709754435844 P32353 0.9484469890594482 0.9504740238189696 0.9473130106925964 0.9489949941635132 0.00599647080525756 0.5243244171142578 0.0 0.0 51.73407767029414 50.0 1.0 no 8223 chrXII_254495 23283 high_effect YLR056W 634 + TGCACAAGCCTCATCACAAG H|213|D H|213|Y H|213|Q silent|CAC>CAT|H|213 ERG3 ERGosterol biosynthesis 365.0 0 0 0 0 0.6658639301836694 P32353 0.9473130106925964 0.9489949941635132 0.9588389992713928 0.0 0.0 0.0 48.56142618474888 50.0 1.0 no 8224 chrXII_254543 23284 high_effect YLR056W 682 + ATTCTTTCCATCCTGTAGAC S|229|C S|229|F ERG3 ERGosterol biosynthesis 365.0 0 0 0 0 -0.3654332158550932 P32353 0.945252001285553 0.9294660091400146 0.0048046382144093505 0.0018992506666108968 49.555196061681784 40.0 1.0 no 8225 chrXII_261003 23288 essential YLR060W 24 + CAGCAATTATTTGATCTTCT Q|10|E Q|10|* FRS1 phenylalanyl (F)-tRNA Synthetase 595.0 0 1 0 0 0.7250915242220495 P15624 1.0357099771499634 1.0 41.247850705920094 30.0 1.0 no 8226 chrXII_261040r 23289 essential YLR060W 64 - ACATAATTCATCGAACTCTT C|28|S C|28|Y FRS1 phenylalanyl (F)-tRNA Synthetase 595.0 0 0 0 0 0.185422300722333 P15624 0.9443399906158448 0.8333889842033386 0.008324071764945984 0.0032371394336223602 1.1862000226974487 12.719400405883787 38.922724010559314 30.0 1.0 no 8227 chrXII_261041r 23291 essential YLR060W 65 - AACATAATTCATCGAACTCT C|28|S C|28|Y FRS1 phenylalanyl (F)-tRNA Synthetase 595.0 0 0 0 0 -0.1379748268021419 P15624 0.9443399906158448 0.8333889842033386 0.008324071764945984 0.0032371394336223602 1.1862000226974487 12.719400405883787 37.40748539282731 30.0 1.0 no 8228 chrXII_261159 23295 essential YLR060W 180 + TACGATTTGCTTTGTATCGA Y|61|* silent|TAC>TAT|Y|61 FRS1 phenylalanyl (F)-tRNA Synthetase 595.0 0 0 0 0 0.645262355694322 P15624 43.481974091864856 35.0 1.0 no 8229 chrXII_261225r 23297 essential YLR060W 249 - GGCTTGCTTAATTTATAGTC K|89|N silent|AAG>AAA|K|89 S|88|T S|88|N FRS1 phenylalanyl (F)-tRNA Synthetase 595.0 0 1 0 0 -1.2269493864565706 P15624 1.003129959106445 1.0052900314331057 0.9781630039215088 0.4868161082267761 0.566521942615509 0.4886983335018158 43.945569161158524 35.0 1.0 no 8230 chrXII_261246r 23298 essential YLR060W 270 - TCGATGATCAACTTAGTGGT D|97|H D|97|N FRS1 phenylalanyl (F)-tRNA Synthetase 595.0 0 1 0 0 -2.3548997013982182 P15624 0.97290700674057 0.9846000075340272 0.1508312076330185 0.23265233635902405 44.08980852922365 40.0 1.0 yes 8231 chrXII_261409r 23303 essential YLR060W 433 - ATCTAAATCGTGAGTACCCA D|151|H D|151|N FRS1 phenylalanyl (F)-tRNA Synthetase 595.0 0 0 0 0 -1.1979450726809269 P15624 0.8355140089988708 0.937349021434784 0.0037554658483713865 0.019643472507596016 45.7884488210566 40.0 1.0 no 8232 chrXII_261420 23305 essential YLR060W 441 + CACGATTTAGATTCAATTGA H|148|Q silent|CAC>CAT|H|148 FRS1 phenylalanyl (F)-tRNA Synthetase 595.0 0 0 0 0 -0.05141277978786723 P15624 0.8297920227050781 0.0 37.49595122529519 30.0 1.0 no 8233 chrXII_261452 23306 essential YLR060W 473 + TTACAGAGCTCTACCACCAA Y|159|* silent|TAC>TAT|Y|159 FRS1 phenylalanyl (F)-tRNA Synthetase 595.0 0 0 0 0 -0.9701089077492708 P15624 49.33458825387845 45.0 1.0 no 8234 chrXII_261489r 23307 essential YLR060W 513 - AACTCTTGGGTTTGATTCAA E|177|D silent|GAG>GAA|E|177 E|177|Q E|177|K FRS1 phenylalanyl (F)-tRNA Synthetase 595.0 0 0 0 0 -1.1597829431696327 P15624 0.9723650217056274 0.9793789982795716 0.9963589906692504 0.1270352452993393 0.14675258100032804 0.17800064384937286 1.086400032043457 0.21940000355243686 -0.03519999980926514 43.086383017401495 35.0 1.0 no 8235 chrXII_261546r 23309 essential YLR060W 570 - CCTATGTTGTTTTTCTGTTC G|197|R G|197|R FRS1 phenylalanyl (F)-tRNA Synthetase 595.0 0 1 0 0 0.6530045893970933 P15624 0.982234001159668 0.982234001159668 0.4236797690391541 0.4236797690391541 47.51544426405633 35.0 1.0 no 8236 chrXII_261596 23310 essential YLR060W 617 + TCCAGTCTTCCCAGTTATTA P|207|R P|207|L P|207|A P|207|S FRS1 phenylalanyl (F)-tRNA Synthetase 595.0 0 1 0 0 -0.7871827159817112 P15624 0.8745329976081848 0.9295629858970642 0.9732030034065248 0.9671800136566162 0.003989338409155607 0.0047346213832497605 0.0372488833963871 0.069882832467556 53.548377959350546 40.0 1.0 no 8237 chrXII_261718r 23313 essential YLR060W 742 - GATCTCGGCTTTGGTCTTAT E|253|D silent|GAG>GAA|E|253 E|253|Q E|253|K FRS1 phenylalanyl (F)-tRNA Synthetase 595.0 0 0 0 0 -0.032713842783699765 P15624 1.0150500535964966 1.014989972114563 1.0140199661254885 0.5418433547019958 0.2603804767131805 1.0 51.6491767335279 45.0 1.0 no 8238 chrXII_261821 23315 essential YLR060W 842 + ACACAATGGCCAATCCCGTT H|282|Q silent|CAC>CAT|H|282 H|282|D H|282|Y FRS1 phenylalanyl (F)-tRNA Synthetase 595.0 0 0 0 0 -0.4888278848649376 P15624 0.983560025691986 0.9801859855651855 0.972082018852234 0.3147031366825104 1.0 0.4319838881492615 -0.35179999470710754 -0.10459999740123747 -0.19419999420642853 52.65433876801319 50.0 1.0 no 8239 chrXII_261877r 23316 essential YLR060W 901 - ACAGGAGTTGATGTACTTAA C|307|S C|307|Y FRS1 phenylalanyl (F)-tRNA Synthetase 595.0 0 0 0 0 0.2087856696060784 P15624 0.999897003173828 0.990490972995758 0.4407180845737457 1.0 0.09440000355243684 -1.4135999679565432 1.5169999599456787 4.372600078582764 40.999113534385906 35.0 1.0 no 8240 chrXII_261106r 23318 essential YLR060W 130 - CGGCTCCTCCCCGGTTTTCA E|49|D silent|GAG>GAA|E|49 E|49|Q E|49|K FRS1 phenylalanyl (F)-tRNA Synthetase 595.0 0 0 0 0 -1.3059309623744526 P15624 1.0123499631881714 1.0224299430847168 1.010640025138855 0.5171151161193848 0.6974179744720459 0.7353087663650513 0.17339999973773956 0.01240000035613775 -0.1005999967455864 65.42537958544085 65.0 1.0 no 8241 chrXII_261986 23320 essential YLR060W 1007 + CATCTTGCACGTTGACATTC I|337|M silent|ATC>ATT|I|337 FRS1 phenylalanyl (F)-tRNA Synthetase 595.0 0 0 0 0 1.1249774071461018 P15624 0.9780169725418092 0.11800436675548552 0.4196000099182129 47.24307900793167 45.0 1.0 no 8242 chrXII_262163 23321 essential YLR060W 1184 + TGCATCCTCTCAAGCCACGT A|396|G A|396|V S|397|C S|397|F FRS1 phenylalanyl (F)-tRNA Synthetase 595.0 0 0 0 0 0.3105201630966648 P15624 0.9600039720535278 1.0000699758529663 1.0018600225448608 0.968388020992279 0.10026316344738008 0.047889932990074165 0.3846172690391541 0.2383676916360855 1.13919997215271 0.1972000002861023 57.224823283751796 55.00000000000001 1.0 no 8243 chrXII_262169 23324 essential YLR060W 1190 + CTCTCAAGCCACGTGGGTTG S|398|C S|398|F Q|399|E Q|399|* FRS1 phenylalanyl (F)-tRNA Synthetase 595.0 0 0 0 0 -2.9682071511870007 P15624 0.9437320232391356 0.9441419839859008 1.012719988822937 0.0044235712848603725 0.0017249190714210274 0.6012610793113708 -0.15620000660419464 3.1010000705718994 55.21982117851866 60.0 1.0 yes 8244 chrXII_262233 23326 essential YLR060W 1254 + TTTCTAAGACAATCCGACAA L|420|V silent|CTA>TTA|L|420 FRS1 phenylalanyl (F)-tRNA Synthetase 595.0 0 1 0 0 0.4846876962286675 P15624 0.9739270210266112 0.008335303515195847 2.871999979019165 39.92056117466439 35.0 1.0 no 8245 chrXII_267202 23331 essential YLR066W 33 + TCGAACCAGGCCTTTTCAAT S|12|W S|12|L N|13|K silent|AAC>AAT|N|13 SPC3 Signal Peptidase Complex 184.0 0 0 0 0 0.2683119076077771 Q12133 0.9288619756698608 0.9298099875450134 0.9439849853515624 0.02632660232484341 0.13756756484508514 0.049965132027864456 49.681887050739995 45.0 1.0 no 8246 chrXII_267410 23333 essential YLR066W 241 + ATCTCACTCCCCTATTCAAT L|82|V L|82|F silent|CTC>CTG|L|82 silent|CTC>CTT|L|82 SPC3 Signal Peptidase Complex 184.0 0 0 0 0 0.3820517611818325 Q12133 0.9512209892272948 0.9587849974632264 0.034720301628112786 0.28926166892051697 51.34002687357349 40.0 1.0 no 8247 chrXII_267420r 23334 essential YLR066W 254 - GCTTTGTATTCCAATTGAAT K|91|N silent|AAG>AAA|K|91 SPC3 Signal Peptidase Complex 184.0 0 0 0 0 0.2747459359287913 Q12133 0.9355990290641784 0.0 42.03727888758056 30.0 1.0 no 8248 chrXII_267488 23336 essential YLR066W 319 + TAACAAGTGAGGTAACATTT T|108|R T|108|I SPC3 Signal Peptidase Complex 184.0 0 0 0 0 0.9951225302534884 Q12133 0.9476869702339172 0.9472420215606691 0.5266115665435791 0.4324048459529877 36.54943285391182 30.0 1.0 no 8249 chrXII_276284 23337 essential YLR071C 2323 - ATACAATCGTATTTGGGAAT L|780|F silent|TTG>TTA|L|780 RGR1 Resistant to Glucose Repression 1082.0 0 0 0 0 -0.5175357992385248 P19263 0.9587849974632264 0.02660446241497993 38.429375400236665 30.0 0.0 no 8250 chrXII_276323 23338 essential YLR071C 2284 - AAACATGGAACTTTCTAATA M|767|I M|767|I RGR1 Resistant to Glucose Repression 1082.0 0 0 0 0 -0.6243726462257391 P19263 0.9553959965705872 0.9553959965705872 0.2591308653354645 0.2591308653354645 33.824981807248605 25.0 0.0 no 8251 chrXII_276367r 23339 essential YLR071C 2237 + TCTAGAATTGGAGTCATTTT L|747|V silent|CTA>TTA|L|747 RGR1 Resistant to Glucose Repression 1082.0 0 0 0 0 0.6961881623031834 P19263 0.9512209892272948 0.13501493632793427 40.527675391649495 30.0 0.0 no 8252 chrXII_276406 23341 essential YLR071C 2201 - TATCATTAGTATTACTTCCT D|740|H D|740|N RGR1 Resistant to Glucose Repression 1082.0 0 0 0 0 0.06868183619304058 P19263 0.9486550092697144 0.956179976463318 0.3225650191307068 0.7881786823272705 41.39504735671522 25.0 0.0 no 8253 chrXII_276478 23342 essential YLR071C 2129 - TCTTATTGCGAATTTCTAGT K|716|N silent|AAG>AAA|K|716 RGR1 Resistant to Glucose Repression 1082.0 0 0 0 0 0.4226317879108121 P19263 0.9355990290641784 0.0616021640598774 41.85507632804212 30.0 0.0 no 8254 chrXII_276586r 23343 essential YLR071C 2018 + CAACGTGATGACTGTCAAAT N|674|K silent|AAC>AAT|N|674 RGR1 Resistant to Glucose Repression 1082.0 0 0 0 0 0.3865960423656672 P19263 0.9439849853515624 0.09213442355394363 40.02817459523828 40.0 0.0 no 8255 chrXII_276423r 23344 essential YLR071C 2181 + CTACCTCAATATATTATCCA P|729|A P|729|S P|729|R P|729|L RGR1 Resistant to Glucose Repression 1082.0 0 0 0 0 -0.2005764879746708 P19263 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.10932981222867966 0.0771431103348732 0.3374680876731873 0.047119610011577606 42.1745439036344 30.0 0.0 no 8256 chrXII_276673r 23345 essential YLR071C 1931 + CTCTAAAACATCATGTGTGG S|645|C S|645|F RGR1 Resistant to Glucose Repression 1082.0 0 0 0 0 -1.8027480450572009 P19263 0.945252001285553 0.9294660091400146 0.0 0.0 40.29725286013979 40.0 0.0 no 8257 chrXII_276905 23348 essential YLR071C 1702 - CCATCCCGTGTTTTCAAACA W|574|S W|574|* G|573|A G|573|E RGR1 Resistant to Glucose Repression 1082.0 0 0 0 0 -1.6068031764298794 P19263 0.8858469724655151 0.9499930143356324 0.9438679814338684 0.0 0.0 0.0 50.61700409428772 45.0 0.0 no 8258 chrXII_277096 23354 essential YLR071C 1511 - CCATGGAAACACATGTGGTA M|510|I M|510|I RGR1 Resistant to Glucose Repression 1082.0 0 0 0 0 -0.03819414675461623 P19263 0.9553959965705872 0.9553959965705872 0.4413618445396423 0.4413618445396423 45.29130654545065 45.0 0.0 no 8259 chrXII_277279r 23360 essential YLR071C 1325 + GGACAACCAGAGTGCATCAA D|443|E silent|GAC>GAT|D|443 N|444|K silent|AAC>AAT|N|444 RGR1 Resistant to Glucose Repression 1082.0 0 0 0 0 -1.0906510273204486 P19263 0.9532920122146606 0.9439849853515624 0.7466417551040649 0.671619176864624 48.15297948261304 50.0 0.0 no 8260 chrXII_277581 23363 essential YLR071C 1026 - TCTAATCTTGGCTTATTCAA E|349|Q E|349|K R|347|T R|347|K RGR1 Resistant to Glucose Repression 1082.0 0 0 0 0 0.3992654598638084 P19263 0.956179976463318 0.9475290179252625 0.932735025882721 0.955805003643036 0.13667689263820648 0.13049529492855072 0.10132144391536713 0.9374950528144836 41.56177459574889 30.0 0.0 no 8261 chrXII_277585 23364 essential YLR071C 1022 - ATCTTGGCTTATTCAAAGGA R|347|T R|347|K RGR1 Resistant to Glucose Repression 1082.0 0 0 0 0 0.027547137656885767 P19263 0.932735025882721 0.955805003643036 0.10132144391536713 0.9374950528144836 43.02209383499804 35.0 0.0 no 8262 chrXII_277747 23366 essential YLR071C 860 - GTCTATTAACAGTCGATAAC R|293|T R|293|K RGR1 Resistant to Glucose Repression 1082.0 0 0 0 0 0.4161141646058292 P19263 0.932735025882721 0.955805003643036 0.3184153139591217 0.7743446826934814 38.32899214174996 35.0 0.0 no 8263 chrXII_277765 23367 essential YLR071C 842 - ACTGGATTTCAAATTCATTA Q|287|H silent|CAG>CAA|Q|287 RGR1 Resistant to Glucose Repression 1082.0 0 0 0 0 0.228367937053434 P19263 0.9570760130882264 0.3201550841331482 37.245345096667045 25.0 0.0 no 8264 chrXII_278177r 23376 essential YLR071C 427 + AACTTTACGTGCTTGTGAAA L|144|V L|144|F RGR1 Resistant to Glucose Repression 1082.0 0 0 0 0 0.2455724492168167 P19263 0.9512209892272948 0.9587849974632264 0.03034087270498276 0.022260045632719997 40.772742615541354 35.0 0.0 no 8265 chrXII_278336r 23377 essential YLR071C 268 + TCAGTCTGGCATTAGTAATA silent|GTC>GTG|V|90 silent|GTC>GTT|V|90 L|92|V silent|CTG>TTG|L|92 RGR1 Resistant to Glucose Repression 1082.0 0 0 0 0 0.1895198432379412 P19263 0.9512209892272948 0.0 43.87892200190646 35.0 0.0 no 8266 chrXII_277096r 23381 essential YLR071C 1508 + CCCTACCACATGTGTTTCCA P|504|R P|504|L P|504|A P|504|S RGR1 Resistant to Glucose Repression 1082.0 0 0 0 0 0.05035195195880855 P19263 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.09764912724494934 0.9045896530151368 0.3320184648036957 0.163778617978096 56.92180320805272 50.0 0.0 no 8267 chrXII_278434r 23382 essential YLR071C 170 + CCAAAAAGAATCTCTAGAAA Q|58|E Q|58|* RGR1 Resistant to Glucose Repression 1082.0 0 0 0 0 0.6905997446771566 P19263 0.9590039849281312 32.99452505029302 30.0 0.0 no 8268 chrXII_278409 23383 essential YLR071C 198 - GTCGCTGCACTTGTATCTTT silent|GCG>GCC|A|72 silent|GCG>GCA|A|72 A|72|P A|72|T RGR1 Resistant to Glucose Repression 1082.0 0 0 0 0 0.6334634560353534 P19263 0.9573720097541808 0.9523990154266356 0.2528015077114105 0.5164386630058289 52.67077507485874 45.0 0.0 no 8269 chrXII_278438 23384 essential YLR071C 169 - TTCTAGAGATTCTTTTTGGG E|63|Q E|63|K RGR1 Resistant to Glucose Repression 1082.0 0 0 0 0 0.250257645687955 P19263 0.956179976463318 0.9475290179252625 43.060790355436666 35.0 0.0 no 8270 chrXII_278461r 23385 essential YLR071C 143 + TGCAACCGACCCGGAAACTA A|49|G A|49|V T|50|S T|50|I RGR1 Resistant to Glucose Repression 1082.0 0 0 0 0 -0.07885742726134848 P19263 0.9484469890594482 0.9504740238189696 0.9491789937019348 0.9472420215606691 49.944564346024826 55.00000000000001 0.0 no 8271 chrXII_278492 23388 essential YLR071C 115 - ATGCAGTTGAGTGTTCTTAA silent|CTG>CTC|L|44 silent|CTG>CTA|L|44 RGR1 Resistant to Glucose Repression 1082.0 0 0 0 0 -1.4030903714136471 P19263 44.583979811955366 35.0 0.0 no 8272 chrXII_278583 23391 essential YLR071C 24 - TCCTCATTAGCCAGCATTTG E|14|D silent|GAG>GAA|E|14 E|15|Q E|15|K RGR1 Resistant to Glucose Repression 1082.0 0 0 0 0 -2.5479762561446453 P19263 0.94931298494339 0.956179976463318 0.9475290179252625 52.46577888406824 45.0 0.0 yes 8273 chrXII_278585 23394 essential YLR071C 22 - CTCATTAGCCAGCATTTGTG E|14|Q E|14|K RGR1 Resistant to Glucose Repression 1082.0 0 0 0 0 0.17599797042552062 P19263 0.956179976463318 0.9475290179252625 50.17821229297391 45.0 0.0 no 8274 chrXII_283061 23398 essential YLR075W 134 + ATTCCCATTGTGTGTCCATT F|46|L silent|TTC>TTT|F|46 P|47|A P|47|S RPL10 Ribosomal Protein of the Large subunit 221.0 0 0 0 0 0.4410092067252546 P41805 0.9387490153312684 0.9562489986419678 0.9498909711837769 0.05945343896746635 0.1216479241847992 0.1323547214269638 1.0040199756622314 1.84935998916626 2.5617599487304688 53.961080003514326 40.0 1.0 no 8275 chrXII_283141r 23399 essential YLR075W 217 - GACAGTAGTCATGTACTTGT V|79|L V|79|I RPL10 Ribosomal Protein of the Large subunit 221.0 0 1 0 0 -4.901974656677981 P41805 0.9539830088615416 0.9574310183525084 0.6743850111961365 0.4246218800544739 -0.4817399978637695 -0.5439000129699707 46.300339938881166 40.0 1.0 yes 8276 chrXII_283087r 23400 essential YLR075W 163 - AGACAATTGTTCCAATTCGT L|60|F silent|TTG>TTA|L|60 RPL10 Ribosomal Protein of the Large subunit 221.0 0 0 0 0 -0.3294234517347116 P41805 0.9587849974632264 0.052409999072551734 -0.4718199968338013 43.41861475373161 35.0 1.0 no 8277 chrXII_283208r 23403 essential YLR075W 284 - TCTTGTTGATTCTCAAGACA K|101|N silent|AAG>AAA|K|101 RPL10 Ribosomal Protein of the Large subunit 221.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.6289194436167869 P41805 0.9355990290641784 0.003948020748794079 0.21734000742435453 43.06148149152335 35.0 1.0 no 8278 chrXII_283290r 23406 essential YLR075W 366 - ACACGAGCGGCCAAACCGTG R|128|P R|128|H V|129|L V|129|I RPL10 Ribosomal Protein of the Large subunit 221.0 0 0 0 0 -6.213211486861399 P41805 0.9099509716033936 0.9570810198783876 0.9539830088615416 0.9574310183525084 0.01707405410706997 0.012009059078991413 0.08737105131149292 0.12322285771369935 -0.8307200074195862 1.6344599723815918 -0.04397999867796898 -0.978659987449646 53.44621965654932 65.0 1.0 yes 8279 chrXII_283356 23407 essential YLR075W 429 + AACAAGGATGTTGTCGTTGA N|144|K silent|AAC>AAT|N|144 RPL10 Ribosomal Protein of the Large subunit 221.0 0 1 0 0 -0.4699082218215743 P41805 0.9439849853515624 0.14181992411613464 0.5671799778938293 43.12620951590304 40.0 1.0 no 8280 chrXII_286200r 23412 essential YLR078C 248 + CGACTTTACTGCCAAGTTTA D|84|E silent|GAC>GAT|D|84 BOS1 Bet One Suppressor 244.0 0 0 0 0 -0.18181572625502854 P25385 0.9532920122146606 0.938167929649353 45.95170921102073 40.0 0.0 no 8281 chrXII_286390 23415 essential YLR078C 61 - CACAGAATTCTTTTCAAACC V|27|L V|27|M BOS1 Bet One Suppressor 244.0 0 0 0 0 0.32471904414003705 P25385 0.9539830088615416 0.9587630033493042 0.8313620090484619 0.2593167722225189 39.68599357845403 35.0 0.0 no 8282 chrXII_302294 23417 essential YLR086W 51 + CCAGAATTATCTCTTGATCA P|18|R P|18|L 0 0 0 0 0.5274686684195714 Q12267 0.9432820081710817 0.9430609941482544 0.4589700102806091 0.3150441646575928 43.17967624668722 35.0 1.0 no 8283 chrXII_302322r 23418 essential YLR086W 82 - TTCTACCTGCGAATCTTCTT E|34|Q E|34|K V|33|L V|33|I 0 0 0 0 -0.16650679122958792 Q12267 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.2297888696193695 0.26403459906578064 0.4240754544734955 0.3095055818557739 48.51307972741472 40.0 1.0 no 8284 chrXII_302474r 23422 essential YLR086W 234 - GACGTGGTTGTTGAGTTTGT silent|ACG>ACC|T|84 silent|ACG>ACA|T|84 0 0 0 0 0.7822021762577882 Q12267 49.796583986396634 45.0 1.0 no 8285 chrXII_302519 23424 essential YLR086W 276 + CCACCAAAAACCTCTTCTAG P|94|A P|94|S P|93|R P|93|L 0 0 0 0 -0.06600132091036512 Q12267 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.7983810901641846 1.0 0.3414758443832397 0.19941775500774386 45.302911712213195 45.0 1.0 no 8286 chrXII_302556 23425 essential YLR086W 313 + CCTACTCTCAATCACCACCA silent|TCC>TCG|S|105 silent|TCC>TCT|S|105 Y|106|* silent|TAC>TAT|Y|106 0 0 1 Series([], Name: modification, dtype: object) 0 -0.9067011735584 Q12267 53.3199330468629 50.0 1.0 no 8287 chrXII_302518 23426 essential YLR086W 275 + ACCACCAAAAACCTCTTCTA P|93|R P|93|L P|93|A P|93|S 0 0 0 0 0.3623468335542809 Q12267 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.3414758443832397 0.19941775500774386 0.6970646977424622 0.4740786850452423 45.64702091252303 40.0 1.0 no 8288 chrXII_302594r 23429 essential YLR086W 354 - AGCAATTCTAATCTTCTAGT L|124|F silent|TTG>TTA|L|124 0 1 0 0 0.5857930668465284 Q12267 0.9587849974632264 0.14371950924396515 41.43027505044517 30.0 1.0 no 8289 chrXII_302649 23432 essential YLR086W 406 + AACTACAAAAAATTTATGAT L|137|V silent|CTA>TTA|L|137 Q|138|E Q|138|* 0 0 0 0 -0.5598963634692695 Q12267 0.9512209892272948 0.9590039849281312 0.4761603176593781 0.905714511871338 27.32591021804984 15.0 1.0 no 8290 chrXII_302674r 23433 essential YLR086W 434 - TCTGTTGCTTGCTCGACGAC Q|151|H silent|CAG>CAA|Q|151 0 1 0 0 1.0727767027155464 Q12267 0.9570760130882264 0.09706774353981018 52.73375323731574 55.00000000000001 1.0 no 8291 chrXII_302739r 23434 essential YLR086W 499 - TACTACTTGTTTACCAGCGT V|173|L V|173|I V|172|L V|172|I 0 0 0 0 -0.7871743525467587 Q12267 0.9539830088615416 0.9574310183525084 0.9539830088615416 0.9574310183525084 0.08810128271579742 1.0 0.3556182384490967 0.6129836440086365 48.51699593305176 40.0 1.0 no 8292 chrXII_302627r 23435 essential YLR086W 387 - TCAACCCTGCTATTTTTCAC E|136|Q E|136|K V|135|L V|135|I 0 0 0 0 -0.4644154468959196 Q12267 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.4458071291446686 0.6504198312759399 0.6279978752136229 0.5427939891815186 48.61670919707132 40.0 1.0 no 8293 chrXII_302770 23438 essential YLR086W 527 + TCATACTAGCTTCTCGGCCG H|177|D H|177|Y T|178|S T|178|I 0 0 0 0 0.5729729101011442 Q12267 0.9473130106925964 0.9489949941635132 0.9491789937019348 0.9472420215606691 0.06170859187841416 0.010851366445422173 1.0 0.025171449407935143 54.44658153104013 55.00000000000001 1.0 no 8294 chrXII_302954 23443 essential YLR086W 711 + TACGTTATTGATGAATCTTC Y|238|* silent|TAC>TAT|Y|238 0 0 0 0 -0.15852952865192393 Q12267 37.79291951788167 30.0 1.0 no 8295 chrXII_303027r 23445 essential YLR086W 787 - TTTCGATGAGTTGTTTTTAA silent|TCG>TCC|S|268 silent|TCG>TCA|S|268 0 0 0 0 0.6480699896993245 Q12267 38.61062548829898 25.0 1.0 no 8296 chrXII_303128 23446 essential YLR086W 885 + AAACGATTTTTAATTCTACA R|297|G R|297|* 0 0 0 0 0.05394368149398751 Q12267 0.8994590044021606 0.0 33.272751295854285 20.0 1.0 no 8297 chrXII_303179r 23447 essential YLR086W 939 - TCACTCTCTTTTTCTGCTTT S|319|T S|319|N D|320|H D|320|N 0 0 0 0 0.03325966882940918 Q12267 0.9512869715690612 0.9536849856376648 0.9486550092697144 0.956179976463318 0.10977807641029358 1.0 0.00830433052033186 0.02176159061491489 49.75197591630342 35.0 1.0 no 8298 chrXII_303254r 23450 essential YLR086W 1014 - CCCATTCGCTCTTCAATTAA M|344|I M|344|I G|345|R G|345|R 0 0 0 0 -0.3647231724815226 Q12267 0.9553959965705872 0.9553959965705872 0.941340982913971 0.941340982913971 0.4159804582595825 0.4159804582595825 0.5285279750823975 0.5285279750823975 47.959988123763644 40.0 1.0 no 8299 chrXII_303454 23452 essential YLR086W 1211 + CTCTAAACTTGCCAGCACCT S|405|C S|405|F 0 0 0 0 -0.1926178224107836 Q12267 0.945252001285553 0.9294660091400146 0.046147819608449936 0.043944399803876884 52.384667872490866 50.0 1.0 no 8300 chrXII_303486r 23453 essential YLR086W 1246 - TTCGAGGTCTTTATTCGAAG E|422|Q E|422|K 0 0 0 0 -0.7436370593093313 Q12267 0.956179976463318 0.9475290179252625 0.5966947078704834 0.5576516389846802 42.894080613357744 40.0 1.0 no 8301 chrXII_303616r 23454 essential YLR086W 1376 - ATTCTCTTCTTTCTAAAACC E|465|Q E|465|K R|464|T R|464|K 0 0 0 0 -0.22185523689202288 Q12267 0.956179976463318 0.9475290179252625 0.932735025882721 0.955805003643036 0.5559150576591492 1.0 0.1768459975719452 1.0 40.63067882207008 30.0 1.0 no 8302 chrXII_303744r 23456 essential YLR086W 1504 - AAGCTCTTCAAGCATATTCT E|507|D silent|GAG>GAA|E|507 E|507|Q E|507|K 0 0 0 0 -0.528611368629904 Q12267 0.94931298494339 0.956179976463318 0.9475290179252625 0.5828288197517395 0.4235743284225464 0.6438645720481873 44.602075965584724 35.0 1.0 no 8303 chrXII_303772 23457 essential YLR086W 1529 + ACAACAAACCGAACACGAGA Q|511|E Q|511|* Q|512|E Q|512|* 0 0 0 0 -0.7733763817381508 Q12267 0.9590039849281312 0.9590039849281312 1.0 1.0 40.2124250484456 45.0 1.0 no 8304 chrXII_303928r 23460 essential YLR086W 1688 - ATTCTTTTTCCTGAAGTTGG E|569|Q E|569|K 0 0 0 0 0.8401317034821573 Q12267 0.956179976463318 0.9475290179252625 0.7433147430419922 0.4624572098255158 -0.4740000069141388 -0.5428000092506409 44.90791735721075 35.0 1.0 no 8305 chrXII_304084r 23461 essential YLR086W 1844 - TCAGCTTCTTTTTCAGATCG silent|CTG>CTC|L|621 silent|CTG>CTA|L|621 K|620|N silent|AAG>AAA|K|620 0 0 0 0 0.18035628777373447 Q12267 0.9355990290641784 0.0633637011051178 0.7829999923706055 47.089201205493744 40.0 1.0 no 8306 chrXII_304192 23462 essential YLR086W 1949 + CGCGCATCGCCAGCGTGCAA A|651|G A|651|V H|652|D H|652|Y 0 0 0 0 -0.15548889207359698 Q12267 0.9484469890594482 0.9504740238189696 0.9473130106925964 0.9489949941635132 0.4058963656425476 0.3764633536338806 0.21688020229339602 1.0 0.6582000255584717 -0.14920000731945038 1.0290000438690186 -0.7925999760627747 59.95232161646305 70.0 1.0 no 8307 chrXII_304201r 23463 essential YLR086W 1961 - ATCTAGCTTCCATTGCACGC R|660|T R|660|K A|659|P A|659|T 0 0 0 0 0.09480307668394254 Q12267 0.932735025882721 0.955805003643036 0.9573720097541808 0.9523990154266356 0.12758944928646088 0.7752333283424377 0.034446317702531815 0.0457899309694767 0.15060000121593475 -0.38960000872612 3.2374000549316406 0.5878000259399414 54.0331711547144 50.0 1.0 no 8308 chrXII_304224r 23464 essential YLR086W 1984 - ATTCTGAGCTTTTGATAAAG Q|667|H silent|CAG>CAA|Q|667 0 0 0 0 -0.04073243471795146 Q12267 0.9570760130882264 0.013099792413413523 0.5117999911308289 37.45021796804241 30.0 1.0 no 8309 chrXII_304306r 23467 essential YLR086W 2066 - CCAAATCGCCCAAACGTCCA L|695|F silent|TTG>TTA|L|695 D|694|H D|694|N 0 0 0 0 -0.1009537226884314 Q12267 0.9587849974632264 0.9486550092697144 0.956179976463318 0.0 0.04083721712231636 0.3569633662700653 2.306999921798706 0.5910000205039978 0.3337999880313873 51.94907869805599 55.00000000000001 1.0 no 8310 chrXII_304373r 23468 essential YLR086W 2133 - ACCACGACATCATCTAGTCT silent|GTG>GTC|V|717 silent|GTG>GTA|V|717 V|718|L V|718|I 0 0 0 0 -1.2006338064227478 Q12267 0.9539830088615416 0.9574310183525084 0.0484834685921669 0.07973635941743851 0.07079999893903732 2.013000011444092 49.453286819949426 45.0 1.0 no 8311 chrXII_304502r 23469 essential YLR086W 2262 - ACATTTTCTGGTGTACTGAT V|761|L V|761|I 0 0 0 0 -0.5525487317052152 Q12267 0.9539830088615416 0.9574310183525084 0.07321643084287642 0.2515137195587158 -1.1128000020980835 -1.2364000082015991 44.93378378286485 35.0 1.0 no 8312 chrXII_304623 23470 essential YLR086W 2380 + AAGCCAATAATGTAGCATAT A|795|G A|795|V silent|GCC>GCG|A|795 silent|GCC>GCT|A|795 0 0 0 0 0.6682424457375111 Q12267 0.9484469890594482 0.9504740238189696 0.0 0.0 0.6480000019073486 0.1477999985218048 39.66205050468221 30.0 1.0 no 8313 chrXII_304626r 23471 essential YLR086W 2386 - CTTCCCATATGCTACATTAT silent|GGG>GGC|G|801 silent|GGG>GGA|G|801 G|801|A G|801|E 0 0 0 0 0.2811143367271256 Q12267 0.9499930143356324 0.9438679814338684 0.0 0.0 0.5659999847412109 1.0327999591827393 47.0641999103264 35.0 1.0 no 8314 chrXII_304720r 23473 essential YLR086W 2480 - TCATTAGACCTTTTGCTACA M|833|I M|833|I 0 0 0 0 0.05554880166964884 Q12267 0.9553959965705872 0.9553959965705872 0.0 0.0 1.2065999507904053 1.2065999507904053 46.09866272254385 35.0 1.0 no 8315 chrXII_304785r 23475 essential YLR086W 2545 - CTCAATTTTATCTACTTCCT E|855|Q E|855|K 0 0 0 0 1.0040930843756848 Q12267 0.956179976463318 0.9475290179252625 0.2558806836605072 0.4222255349159241 5.695183992508951e-15 -0.4526000022888184 43.432975542161046 30.0 1.0 no 8316 chrXII_304784r 23476 essential YLR086W 2544 - TCAATTTTATCTACTTCCTC E|855|Q E|855|K 0 0 0 0 0.2564767705316599 Q12267 0.956179976463318 0.9475290179252625 0.2558806836605072 0.4222255349159241 5.695183992508951e-15 -0.4526000022888184 42.53889384450178 30.0 1.0 no 8317 chrXII_304834 23477 essential YLR086W 2591 + CTTCCGCGTGGCAAGCGATA F|865|L silent|TTC>TTT|F|865 R|866|G R|866|C 0 0 0 0 -1.1539892301198007 Q12267 0.9387490153312684 0.8994590044021606 0.8926740288734436 0.07750986516475677 0.2326977550983429 0.03304464370012283 -0.7009999752044678 1.9077999591827397 1.5068000555038452 55.12558985833374 60.0 1.0 no 8318 chrXII_304858r 23480 essential YLR086W 2618 - TCAGTTCTTCCTCCATCTCG silent|CTG>CTC|L|879 silent|CTG>CTA|L|879 E|878|Q E|878|K 0 0 0 0 -0.4018659026936556 Q12267 0.956179976463318 0.9475290179252625 0.5825743079185486 1.0 -0.15000000596046448 -0.8366000056266785 55.873681234962866 50.0 1.0 no 8319 chrXII_305020 23484 essential YLR086W 2777 + TGACAAAGCGCAACTAAACG D|927|E silent|GAC>GAT|D|927 0 0 0 0 -0.0712965215823077 Q12267 0.9532920122146606 1.0 0.576200008392334 38.977783479066034 45.0 1.0 no 8320 chrXII_305102 23485 essential YLR086W 2859 + ACTAAAAAGGAAAAGATCAA T|954|S T|954|I 0 0 0 0 0.4462437896820963 Q12267 0.9491789937019348 0.9472420215606691 0.9135652780532836 0.4454342722892761 28.680488516164473 25.0 1.0 no 8321 chrXII_305240 23487 essential YLR086W 2997 + TCTGCCTCAAAGAAGTCAGG S|1000|C S|1000|F A|1001|G A|1001|V 0 0 0 0 -1.4120963976172711 Q12267 0.945252001285553 0.9294660091400146 0.9484469890594482 0.9504740238189696 0.07413245737552643 0.13462021946907046 0.3723797798156738 0.2821922302246094 47.69106252910473 50.0 1.0 no 8322 chrXII_316188 23488 essential YLR088W 81 + TCCATGCTATGCGCTCTATT silent|TCC>TCG|S|28 silent|TCC>TCT|S|28 S|28|C S|28|F GAA1 GPI Anchor Attachment 614.0 0 0 0 1 -0.4108674363595137 P39012 0.945252001285553 0.9294660091400146 0.0 0.0 53.11320672614517 45.0 1.0 no 8323 chrXII_316189 23491 essential YLR088W 82 + CCATGCTATGCGCTCTATTT silent|TCC>TCG|S|28 silent|TCC>TCT|S|28 L|30|V silent|CTA>TTA|L|30 GAA1 GPI Anchor Attachment 614.0 0 0 0 0 -0.1000078965904927 P39012 0.9512209892272948 0.2506827414035797 52.26228558726632 45.0 1.0 no 8324 chrXII_316217 23492 essential YLR088W 110 + TTCTATAGCTATTCTGCCTA S|38|C S|38|F GAA1 GPI Anchor Attachment 614.0 0 0 0 0 0.8173384971086376 P39012 0.945252001285553 0.9294660091400146 0.05472422018647194 0.6891013979911804 48.19330015646654 35.0 1.0 no 8325 chrXII_316476 23494 essential YLR088W 369 + ATGCACGCTCCTAGGGGTGA H|125|D H|125|Y H|125|Q silent|CAC>CAT|H|125 GAA1 GPI Anchor Attachment 614.0 0 0 0 0 -2.161976557094711 P39012 0.9473130106925964 0.9489949941635132 0.9588389992713928 0.0 0.0 0.0 58.41037912932808 60.0 1.0 yes 8326 chrXII_316485r 23495 essential YLR088W 381 - GCTTCTGTTCCATCACCCCT A|134|P A|134|T E|133|Q E|133|K GAA1 GPI Anchor Attachment 614.0 0 0 0 0 -0.7016116344480543 P39012 0.9573720097541808 0.9523990154266356 0.956179976463318 0.9475290179252625 0.0 0.0 0.0 0.0 63.04000635135725 55.00000000000001 1.0 no 8327 chrXII_316519r 23496 essential YLR088W 415 - ATCTGAATTAAACCATGGAA D|145|H D|145|N GAA1 GPI Anchor Attachment 614.0 0 0 0 0 0.2989428666172672 P39012 0.9486550092697144 0.956179976463318 0.01091158576309681 0.1560041308403015 36.874051970966256 30.0 1.0 no 8328 chrXII_316582 23498 essential YLR088W 475 + TAGCAAGATTTTTCTCACGT A|160|G A|160|V GAA1 GPI Anchor Attachment 614.0 0 0 0 0 0.242256183229502 P39012 0.9484469890594482 0.9504740238189696 0.044223502278327935 0.1634831428527832 43.773811701074926 35.0 1.0 no 8329 chrXII_316648 23499 essential YLR088W 541 + CTCGTGCAGCATTAAGATCA R|182|G R|182|C A|183|G A|183|V GAA1 GPI Anchor Attachment 614.0 0 0 0 0 -0.2736547946165956 P39012 0.8994590044021606 0.8926740288734436 0.9484469890594482 0.9504740238189696 0.7198531031608582 0.07893817126750946 0.4554766118526459 0.4310349225997925 47.51634571617672 45.0 1.0 no 8330 chrXII_316686 23502 essential YLR088W 579 + ACTTCCTTAGATTTGACTGG T|194|S T|194|I S|195|C S|195|F GAA1 GPI Anchor Attachment 614.0 0 0 0 0 -0.023369580756018027 P39012 0.9491789937019348 0.9472420215606691 0.945252001285553 0.9294660091400146 0.27359047532081604 0.0070114806294441214 0.032814886420965195 0.026417341083288196 45.78990655673664 40.0 1.0 no 8331 chrXII_316773 23503 essential YLR088W 666 + ATCTCATACGACGGTCTGAA I|223|M silent|ATC>ATT|I|223 S|224|* S|224|L GAA1 GPI Anchor Attachment 614.0 0 0 0 0 0.6054885588376584 P39012 0.9598389863967896 0.9298099875450134 0.4732619822025299 0.6435684561729431 45.690506792703104 45.0 1.0 no 8332 chrXII_316820 23504 essential YLR088W 713 + CAACATCGCTATATCCATTA N|239|K silent|AAC>AAT|N|239 I|240|M silent|ATC>ATT|I|240 GAA1 GPI Anchor Attachment 614.0 0 0 0 0 -0.4911610354251459 P39012 0.9439849853515624 0.9598389863967896 0.0 0.07883607596158981 43.26294566300885 35.0 1.0 no 8333 chrXII_316931r 23506 essential YLR088W 827 - ACGCCCAATCCCTTATTCCC A|282|P A|282|T silent|GCG>GCC|A|282 silent|GCG>GCA|A|282 GAA1 GPI Anchor Attachment 614.0 0 0 0 0 -0.7092021146835122 P39012 0.9573720097541808 0.9523990154266356 0.17368532717227936 0.5026110410690308 59.41809446560211 55.00000000000001 1.0 no 8334 chrXII_316957r 23507 essential YLR088W 853 - ACCATGGGGCTTTTTAACAC G|291|R G|291|S G|291|A G|291|D GAA1 GPI Anchor Attachment 614.0 0 0 0 0 -0.9385067460165492 P39012 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.010221250355243685 0.03684443607926369 0.02310341224074364 0.05804310739040375 48.55626321342396 45.0 1.0 no 8335 chrXII_316956 23508 essential YLR088W 849 + TCCGGTGTTAAAAAGCCCCA silent|TCC>TCG|S|284 silent|TCC>TCT|S|284 S|284|C S|284|F GAA1 GPI Anchor Attachment 614.0 0 0 0 0 -0.08471443573290892 P39012 0.945252001285553 0.9294660091400146 0.026380034163594246 0.015214445069432259 51.89055822407056 50.0 1.0 no 8336 chrXII_316973r 23509 essential YLR088W 869 - CGCTAAATGCCTCGTTACCA S|296|T S|296|N GAA1 GPI Anchor Attachment 614.0 0 0 0 0 0.9486006024368716 P39012 0.9512869715690612 0.9536849856376648 0.0 0.0 50.9524291826433 50.0 1.0 no 8337 chrXII_317010 23512 essential YLR088W 903 + TCTGTAACATTGAAAGCACA S|302|C S|302|F GAA1 GPI Anchor Attachment 614.0 0 0 0 0 -0.26052143756935225 P39012 0.945252001285553 0.9294660091400146 0.013295081444084644 0.0063338102772831925 39.63090094727346 35.0 1.0 no 8338 chrXII_317164r 23514 essential YLR088W 1060 - GCTTGGCAAATAACTACTAA S|360|T S|360|N L|358|F silent|TTG>TTA|L|358 GAA1 GPI Anchor Attachment 614.0 0 0 0 0 0.4423767020565609 P39012 0.9512869715690612 0.9536849856376648 0.9587849974632264 0.040524598211050034 0.018653012812137604 0.0 39.48429712388389 35.0 1.0 no 8339 chrXII_317269r 23515 essential YLR088W 1165 - CAACGCTACCAAATTATACT silent|GCG>GCC|A|394 silent|GCG>GCA|A|394 A|394|P A|394|T GAA1 GPI Anchor Attachment 614.0 0 0 0 0 0.2480958661728417 P39012 0.9573720097541808 0.9523990154266356 0.25305122137069697 0.500555157661438 40.15292230046555 35.0 1.0 no 8340 chrXII_317340 23516 essential YLR088W 1233 + TTTCTTCTAATACCTTCATC L|413|V L|413|F L|414|V silent|CTA>TTA|L|414 GAA1 GPI Anchor Attachment 614.0 0 0 0 0 0.5076133631286944 P39012 0.9512209892272948 0.9587849974632264 0.9512209892272948 0.5082975029945374 0.7033551931381226 0.7466027736663818 42.5388938445019 30.0 1.0 no 8341 chrXII_317352r 23517 essential YLR088W 1248 - GTCATCAATAATCCCGATGA M|422|I M|422|I L|421|F silent|TTG>TTA|L|421 GAA1 GPI Anchor Attachment 614.0 0 0 0 0 0.6770864805493493 P39012 0.9553959965705872 0.9553959965705872 0.9587849974632264 0.4316591918468475 0.4316591918468475 0.5318933129310608 45.0124134097502 40.0 1.0 no 8342 chrXII_317428 23518 essential YLR088W 1321 + TCTCAGAACCACTATCATAC S|442|* S|442|L I|441|M silent|ATC>ATT|I|441 GAA1 GPI Anchor Attachment 614.0 0 0 0 0 -1.028242011256426 P39012 0.9298099875450134 0.9598389863967896 0.023694228380918503 0.2450854778289795 43.56668398480974 40.0 1.0 no 8343 chrXII_316233r 23519 essential YLR088W 129 - CTTCTGTACTGTCCATCCAT R|49|T R|49|K GAA1 GPI Anchor Attachment 614.0 0 0 0 0 -0.965921978942838 P39012 0.932735025882721 0.955805003643036 0.0 0.0 53.5672460994885 45.0 1.0 no 8344 chrXII_341869 23520 essential YLR100W 59 + GTTCCGTCTGATTGAAACTG F|21|L silent|TTC>TTT|F|21 R|22|G R|22|C ERG27 ERGosterol biosynthesis 347.0 0 0 0 0 0.6098966716488967 Q12452 0.9387490153312684 0.8994590044021606 0.8926740288734436 0.7377296686172485 0.011569689959287643 0.0015645697712898257 45.25418098345176 45.0 1.0 no 8345 chrXII_341872r 23521 essential YLR100W 65 - TGTCCTCAGTTTCAATCAGA D|28|H D|28|N E|27|D silent|GAG>GAA|E|27 ERG27 ERGosterol biosynthesis 347.0 0 0 0 0 -0.6393495303608236 Q12452 0.9486550092697144 0.956179976463318 0.94931298494339 0.13324719667434692 0.5468933582305908 0.6183691620826721 48.403838549543714 40.0 1.0 no 8346 chrXII_341895r 23522 essential YLR100W 88 - CACAATGGTCAATCTGACAT V|36|L V|36|M ERG27 ERGosterol biosynthesis 347.0 0 0 0 0 0.004860697957552118 Q12452 0.9539830088615416 0.9587630033493042 0.08482280373573302 0.01593757979571819 42.28471157245161 40.0 1.0 no 8347 chrXII_341977 23524 essential YLR100W 167 + CAACAAATCAGGCCGTGTAG N|57|K silent|AAC>AAT|N|57 ERG27 ERGosterol biosynthesis 347.0 0 1 0 0 0.4076287745187631 Q12452 0.9439849853515624 0.43805077672004705 45.677261802242136 50.0 1.0 no 8348 chrXII_342010 23525 essential YLR100W 200 + AGACTTTGATTATCTGTTGG D|68|E silent|GAC>GAT|D|68 ERG27 ERGosterol biosynthesis 347.0 0 0 0 0 0.35440329823810146 Q12452 0.9532920122146606 1.0 42.02365749525808 35.0 1.0 no 8349 chrXII_342039r 23526 essential YLR100W 232 - GTTCAAGACACTCACCATGT L|83|F silent|TTG>TTA|L|83 ERG27 ERGosterol biosynthesis 347.0 0 0 0 0 -0.0223927731317326 Q12452 0.9587849974632264 0.4663870334625244 48.58436283925232 45.0 1.0 no 8350 chrXII_342070 23528 essential YLR100W 260 + CGACATCAACAAAAAGTACA D|88|E silent|GAC>GAT|D|88 I|89|M silent|ATC>ATT|I|89 ERG27 ERGosterol biosynthesis 347.0 0 0 0 0 -0.05150931433946906 Q12452 0.9532920122146606 0.9598389863967896 0.8150626420974731 0.055594652891159065 35.066715273118355 35.0 1.0 no 8351 chrXII_342174r 23530 essential YLR100W 367 - TGTCACTGCCTCCAATGGAT silent|GTG>GTC|V|128 silent|GTG>GTA|V|128 V|128|L V|128|M ERG27 ERGosterol biosynthesis 347.0 0 0 0 0 -0.7001142402157187 Q12452 0.9539830088615416 0.9587630033493042 0.8468486070632935 0.1151304617524147 53.710393477389744 50.0 1.0 no 8352 chrXII_342226 23532 essential YLR100W 416 + CGTCAAGTCTAAAGATGACA silent|GTC>GTG|V|140 silent|GTC>GTT|V|140 ERG27 ERGosterol biosynthesis 347.0 0 0 0 0 -0.8340331904058862 Q12452 39.96137354267114 40.0 1.0 no 8353 chrXII_342315r 23539 essential YLR100W 508 - AACAATATAAGCCTTTCCCC V|176|L V|176|I ERG27 ERGosterol biosynthesis 347.0 0 0 0 0 0.4828549406646845 Q12452 0.9539830088615416 0.9574310183525084 0.17858673632144928 0.944771945476532 47.4334596329561 40.0 1.0 no 8354 chrXII_342408r 23542 essential YLR100W 601 - ACGCTTGGAGCCCTCATAAG K|206|N silent|AAG>AAA|K|206 R|207|P R|207|H ERG27 ERGosterol biosynthesis 347.0 0 1 0 0 -4.047468055891763 Q12452 0.9355990290641784 0.9099509716033936 0.9570810198783876 0.0 0.04034011065959929 0.0496419370174408 53.30891415486843 55.00000000000001 1.0 yes 8355 chrXII_342456r 23543 essential YLR100W 649 - CAGCTTTTTCAAGTCTTTGT K|222|N silent|AAG>AAA|K|222 ERG27 ERGosterol biosynthesis 347.0 0 0 0 0 -0.16223017077848384 Q12452 0.9355990290641784 0.4956234395503998 46.46976972498096 35.0 1.0 no 8356 chrXII_344498r 23549 essential YLR103C 1421 + TTCGAATTTTTGGCTCAGTT S|475|W S|475|L 0 0 0 0 0.41170432270609736 Q08032 0.9288619756698608 0.9298099875450134 0.01380566507577896 0.10716229677200316 45.447026560419204 35.0 0.0 no 8357 chrXII_344667 23552 essential YLR103C 1255 - GACAAATTCACTGGCACTTA V|425|L V|425|I 0 0 0 0 -0.0019608772120925373 Q08032 0.9539830088615416 0.9574310183525084 0.0 0.0 43.33908125233336 40.0 0.0 no 8358 chrXII_344719r 23554 essential YLR103C 1200 + TTGCAAGATATAATTAGAGA Q|402|E Q|402|* 0 0 0 0 0.2456872135154373 Q08032 0.9590039849281312 1.0 34.005251153346144 25.0 0.0 no 8359 chrXII_344874 23557 essential YLR103C 1048 - TTTCCCATTTTCATTCCATA silent|GGG>GGC|G|355 silent|GGG>GGA|G|355 G|355|A G|355|E 0 0 0 0 0.391822837717388 Q08032 0.9499930143356324 0.9438679814338684 0.0 0.0 48.64771642288854 30.0 0.0 no 8360 chrXII_344883 23558 essential YLR103C 1039 - TTCATTCCATAGGGATAGTT E|353|Q E|353|K W|351|C W|351|* 0 0 0 0 -0.29784622600805033 Q08032 0.956179976463318 0.9475290179252625 0.8858469724655151 0.16569635272026062 0.18755383789539334 0.004398370627313852 46.057705982345794 35.0 0.0 no 8361 chrXII_344889r 23559 essential YLR103C 1030 + TCAATGCCAAACTATCCCTA silent|GTC>GTG|V|344 silent|GTC>GTT|V|344 A|346|G A|346|V 0 0 0 0 0.34270872537892383 Q08032 0.9484469890594482 0.9504740238189696 0.06118782609701156 0.020280873402953148 47.16402783497313 40.0 0.0 no 8362 chrXII_345042 23560 essential YLR103C 880 - CTTCACTTCATCTTGCAATA silent|GTG>GTC|V|299 silent|GTG>GTA|V|299 V|299|L V|299|M 0 0 0 0 0.2043674278869928 Q08032 0.9539830088615416 0.9587630033493042 0.0 0.0 44.35862120623715 35.0 0.0 no 8363 chrXII_345043 23561 essential YLR103C 879 - TTCACTTCATCTTGCAATAA silent|GTG>GTC|V|299 silent|GTG>GTA|V|299 V|299|L V|299|M 0 0 0 0 0.2563874233092567 Q08032 0.9539830088615416 0.9587630033493042 0.0 0.0 41.020342395959524 30.0 0.0 no 8364 chrXII_345044 23562 essential YLR103C 878 - TCACTTCATCTTGCAATAAG V|299|L V|299|M silent|GTG>GTC|V|299 silent|GTG>GTA|V|299 0 0 0 0 0.2429763040957125 Q08032 0.9539830088615416 0.9587630033493042 0.0 0.0 40.80518968198618 35.0 0.0 no 8365 chrXII_345230 23563 essential YLR103C 692 - CCAAAACACCTTCATATTCA L|237|F silent|TTG>TTA|L|237 V|236|L V|236|I 0 0 0 0 0.07187148713619089 Q08032 0.9587849974632264 0.9539830088615416 0.9574310183525084 0.028817534446716312 0.35407209396362305 0.6098318696022034 42.43807286705111 35.0 0.0 no 8366 chrXII_345446r 23565 essential YLR103C 473 + ATACTATAAATTGCTTGAAC Y|159|* silent|TAC>TAT|Y|159 0 0 0 0 -0.06651626638371275 Q08032 33.523923970378625 25.0 0.0 no 8367 chrXII_345505r 23568 essential YLR103C 414 + ATCATCCAATGTTTTGACGA I|139|M silent|ATC>ATT|I|139 I|140|M silent|ATC>ATT|I|140 0 0 0 0 0.6051678519986978 Q08032 0.9598389863967896 0.9598389863967896 0.281794548034668 0.008671365678310394 43.5610898599715 35.0 0.0 no 8368 chrXII_345606r 23570 essential YLR103C 313 + TCGATACAGATGAAAAGTCG I|105|M silent|ATC>ATT|I|105 T|107|R T|107|I 0 0 0 0 -0.3617609970925965 Q08032 0.9598389863967896 0.9476869702339172 0.9472420215606691 0.2394624501466751 0.5257437825202942 0.1943971812725067 37.27861227012989 40.0 0.0 no 8369 chrXII_345608r 23572 essential YLR103C 311 + TATCGATACAGATGAAAAGT I|105|M silent|ATC>ATT|I|105 0 0 0 0 0.4503743077111384 Q08032 0.9598389863967896 0.2394624501466751 34.511467382732405 30.0 0.0 no 8370 chrXII_345682r 23574 essential YLR103C 237 + AGTCTGCTATTAGTAGGGTT L|81|V silent|CTG>TTG|L|81 L|82|V silent|CTA>TTA|L|82 0 0 0 0 -0.8592255826864134 Q08032 0.9512209892272948 0.9512209892272948 1.0 0.12517249584197998 49.52887991091478 40.0 0.0 no 8371 chrXII_345753r 23576 essential YLR103C 166 + CTCAAATAGTACCGATATTT Q|57|E Q|57|* 0 0 0 0 0.4699320783597393 Q08032 0.9590039849281312 0.041485514491796494 38.81469846182529 30.0 0.0 no 8372 chrXII_345754r 23577 essential YLR103C 165 + TCTCAAATAGTACCGATATT Q|57|E Q|57|* S|56|C S|56|F 0 0 0 0 0.13692900667534552 Q08032 0.9590039849281312 0.945252001285553 0.9294660091400146 0.041485514491796494 0.1700562685728073 0.7420925498008728 39.417823513803675 30.0 0.0 no 8373 chrXII_345888 23578 essential YLR103C 34 - ATTCCTTAAGATTTTGTTGT R|17|S silent|AGG>AGA|R|17 R|17|T R|17|K 0 0 0 0 -0.09592671234171056 Q08032 0.9087679982185364 0.932735025882721 0.955805003643036 0.2271773219108581 0.3233736157417297 1.0 41.536604236904225 25.0 0.0 no 8374 chrXII_347359r 23580 essential YLR105C 799 + ATCACTACAGATCACACGGT H|268|D H|268|Y H|268|Q silent|CAC>CAT|H|268 0 0 0 0 -0.2577051065810835 P16658 0.9669790267944336 0.9671300053596495 0.9784529805183412 0.02072663977742195 0.15369608998298645 0.014384638518095016 46.91796615349836 45.0 0.0 no 8375 chrXII_347449r 23581 essential YLR105C 709 + TATCTCCCGCGTGCCTGGCA S|238|C S|238|F P|239|A P|239|S 0 0 0 0 0.09212740538036457 P16658 0.9634199738502502 0.9436050057411194 0.9856799840927124 0.9771999716758728 0.09002736955881119 0.2053876519203186 0.8187558650970459 0.7632653117179871 64.25902019803989 65.0 0.0 no 8376 chrXII_347454r 23582 essential YLR105C 704 + TGACATATCTCCCGCGTGCC D|236|E silent|GAC>GAT|D|236 0 0 0 0 0.8125569461295525 P16658 0.9800329804420472 0.6783720254898071 58.28098049833939 60.0 0.0 no 8377 chrXII_347511r 23583 essential YLR105C 647 + GTCACTAGAACTAATGCCAG S|217|* S|217|L L|218|V silent|CTA>TTA|L|218 0 0 0 0 0.15092000389649776 P16658 0.8951669931411743 0.9796620011329652 0.6703794598579407 0.1444913148880005 44.56051413004673 45.0 0.0 no 8378 chrXII_347667 23585 essential YLR105C 494 - ATTCTCGTTGTTTCTCAAGG E|171|Q E|171|K R|170|P R|170|Q 0 0 0 0 0.3017593879257965 P16658 0.9857460260391236 0.9736970067024232 0.9457839727401732 0.9765419960021972 0.4992875158786774 0.616181492805481 0.24651895463466644 0.4772345423698425 46.47110334321064 40.0 0.0 no 8379 chrXII_347835 23587 essential YLR105C 326 - TCTTTGTTCCTCCCCGATTG K|115|N silent|AAG>AAA|K|115 0 0 0 0 -0.39383072975172506 P16658 0.9665650129318236 56.860457804839704 50.0 0.0 no 8380 chrXII_347888 23593 essential YLR105C 273 - TCTGTTCTAGCTTTCCATGT E|98|Q E|98|K R|96|T R|96|K 0 0 0 0 -0.09435172979782558 P16658 0.9202449917793274 0.9081959724426271 0.9114800095558168 0.9298490285873412 0.2919746041297913 0.3382859230041504 0.0 0.0 52.5497604874576 40.0 0.0 no 8381 chrXII_348105 23598 essential YLR105C 56 - ACTCTGGAAGGTCATCTACG E|25|Q E|25|K E|25|D silent|GAG>GAA|E|25 0 0 0 0 0.09496883876861373 P16658 0.9840490221977234 0.972000002861023 0.9761919975280762 0.4972392022609711 0.7666196823120117 0.6247245669364929 47.62054054544842 50.0 0.0 no 8382 chrXII_342200r 23600 essential YLR100W 393 - ACCAGTTGTATCTTGTATGT silent|CTG>CTC|L|137 silent|CTG>CTA|L|137 V|138|L V|138|M ERG27 ERGosterol biosynthesis 347.0 0 0 0 0 -0.0225157411774351 Q12452 0.9539830088615416 0.9587630033493042 0.22023293375968933 0.0639152079820633 47.423003782829426 35.0 1.0 no 8383 chrXII_352793 23601 essential YLR106C 10926 - TTCTCCTTTGTATATACATT E|3648|D silent|GAG>GAA|E|3648 E|3648|Q E|3648|K MDN1 MiDasiN 4910.0 0 0 0 0 0.22318805018936846 Q12019 0.5922211408615112 0.21715687215328214 0.3776834309101105 42.21251213122037 25.0 0.0 no 8384 chrXII_352794 23602 essential YLR106C 10925 - TCTCCTTTGTATATACATTA E|3648|Q E|3648|K E|3648|D silent|GAG>GAA|E|3648 MDN1 MiDasiN 4910.0 0 0 0 0 0.2943200330552148 Q12019 0.21715687215328214 0.3776834309101105 0.5922211408615112 41.36808921606871 25.0 0.0 no 8385 chrXII_352854r 23603 essential YLR106C 10862 + TAACTTCGCAGATTTAGCAT N|3622|K silent|AAC>AAT|N|3622 F|3623|L silent|TTC>TTT|F|3623 MDN1 MiDasiN 4910.0 0 0 0 0 -0.20943164208002607 Q12019 0.3834730982780457 1.0 43.136120596467826 35.0 0.0 no 8386 chrXII_352857 23604 essential YLR106C 10862 - ATGCTAAATCTGCGAAGTTA A|3627|P A|3627|T MDN1 MiDasiN 4910.0 0 0 0 0 0.6014275920424961 Q12019 0.02302112802863121 0.2561553418636322 40.93545279013688 35.0 0.0 no 8387 chrXII_353001r 23606 essential YLR106C 10715 + TTACGAAGACCCCAACTTAG Y|3573|* silent|TAC>TAT|Y|3573 MDN1 MiDasiN 4910.0 0 0 0 0 -4.2415974876069376 Q12019 45.2929646547093 45.0 0.0 yes 8388 chrXII_353100 23608 essential YLR106C 10619 - CATCCCCATTTAGCAAATCA D|3546|H D|3546|N silent|GGG>GGC|G|3545 silent|GGG>GGA|G|3545 MDN1 MiDasiN 4910.0 0 0 0 0 -0.35448135437846034 Q12019 0.11164790391921996 0.4975182414054871 48.32818884784729 40.0 0.0 no 8389 chrXII_353157 23610 essential YLR106C 10562 - ACTTACGAGAACTTTGTTTC K|3527|N silent|AAG>AAA|K|3527 R|3526|P R|3526|H MDN1 MiDasiN 4910.0 0 0 0 0 1.2742964535999528 Q12019 0.017125485464930534 0.008656878024339676 0.09176891297101973 40.63067882207008 35.0 0.0 no 8390 chrXII_353263r 23611 essential YLR106C 10453 + TCAAACCATTAATTGATGAG F|3485|L silent|TTC>TTT|F|3485 P|3487|A P|3487|S MDN1 MiDasiN 4910.0 0 1 0 0 -0.4176458846755433 Q12019 0.0 0.19606193900108335 0.23057135939598086 35.71366042979355 30.0 0.0 no 8391 chrXII_353338r 23612 essential YLR106C 10378 + ACATTCAACTAATTGGATTG H|3460|Q silent|CAC>CAT|H|3460 Q|3462|E Q|3462|* MDN1 MiDasiN 4910.0 0 1 0 0 0.30504173810471474 Q12019 0.0 0.9387277364730836 36.64526968707281 30.0 0.0 no 8392 chrXII_353345r 23613 essential YLR106C 10371 + TACAAGCACATTCAACTAAT Y|3458|* silent|TAC>TAT|Y|3458 H|3460|D H|3460|Y MDN1 MiDasiN 4910.0 0 1 0 0 -1.284094576641147 Q12019 0.0 0.0 37.339417110552226 30.0 0.0 no 8393 chrXII_353371 23614 essential YLR106C 10348 - TGCTTTTACAAGATCTAGCC A|3456|P A|3456|T MDN1 MiDasiN 4910.0 0 1 0 0 0.16627392117393075 Q12019 0.017508070915937424 0.01768612489104271 46.26916020015477 40.0 0.0 no 8394 chrXII_353442 23615 essential YLR106C 10277 - TTACCAAAAGTGTAGCGTTA V|3432|L V|3432|I L|3431|F silent|TTG>TTA|L|3431 MDN1 MiDasiN 4910.0 0 0 0 0 -1.4605320662633163 Q12019 1.0 0.5262629389762878 0.02384295128285885 41.82562521956135 35.0 0.0 no 8395 chrXII_353605r 23616 essential YLR106C 10111 + TTACAGATTTGATAGTTTCA T|3372|R T|3372|I MDN1 MiDasiN 4910.0 0 0 0 0 0.3736562174545872 Q12019 0.01734498329460621 0.21734586358070374 38.17558769695347 25.0 0.0 no 8396 chrXII_353628 23617 essential YLR106C 10091 - TCAGTTTAACGGTGTTATTC silent|CTG>CTC|L|3370 silent|CTG>CTA|L|3370 MDN1 MiDasiN 4910.0 0 0 0 0 0.7750240625897558 Q12019 42.527986609907934 35.0 0.0 no 8397 chrXII_353722 23618 essential YLR106C 9997 - TCTTGCTAAGGGTGTTTTAA R|3339|T R|3339|K A|3338|P A|3338|T MDN1 MiDasiN 4910.0 0 0 0 0 -0.7255828288459714 Q12019 0.012193407863378523 0.260682612657547 0.12294349074363707 0.13107725977897644 44.27477728949867 35.0 0.0 no 8398 chrXII_353766 23619 essential YLR106C 9953 - AAACTCGATATAATTCTTTG V|3324|L V|3324|I R|3323|P R|3323|Q MDN1 MiDasiN 4910.0 0 0 0 0 0.39830480897312376 Q12019 0.34114086627960205 0.6199906468391418 0.2335932552814484 0.3927536308765411 33.609333920305346 25.0 0.0 no 8399 chrXII_353767 23621 essential YLR106C 9952 - AACTCGATATAATTCTTTGA V|3324|L V|3324|I R|3323|P R|3323|Q MDN1 MiDasiN 4910.0 0 0 0 0 0.1877227387017913 Q12019 0.34114086627960205 0.6199906468391418 0.2335932552814484 0.3927536308765411 35.9416152514405 25.0 0.0 no 8400 chrXII_353803r 23623 essential YLR106C 9913 + TCTTGAAATTGTTGAAGCAG silent|GTC>GTG|V|3305 silent|GTC>GTT|V|3305 MDN1 MiDasiN 4910.0 0 0 0 0 1.1293959542948444 Q12019 38.3700662122198 35.0 0.0 no 8401 chrXII_353852 23624 essential YLR106C 9867 - TCACCTGCTTTTTGAAACTC G|3295|A G|3295|D D|3296|H D|3296|N MDN1 MiDasiN 4910.0 0 0 0 0 0.20613614017105367 Q12019 0.4108566045761109 0.2232419103384018 0.09706786274909973 0.3920514285564423 45.54124143132486 40.0 0.0 no 8402 chrXII_353871r 23626 essential YLR106C 9845 + TTACCACGATTTCTCTATTC Y|3283|* silent|TAC>TAT|Y|3283 H|3284|D H|3284|Y MDN1 MiDasiN 4910.0 0 0 0 0 -0.6116579634824731 Q12019 0.13689084351062775 0.3608650267124176 44.23491253769225 35.0 0.0 no 8403 chrXII_353906r 23627 essential YLR106C 9810 + TTCAAAAACACGGAAGTTTT F|3271|L silent|TTC>TTT|F|3271 MDN1 MiDasiN 4910.0 0 0 0 0 0.049474460049513135 Q12019 0.30057796835899353 35.647749882535145 30.0 0.0 no 8404 chrXII_353977 23628 essential YLR106C 9742 - GCTTTTCAACTCTTCTATCC S|3254|T S|3254|N L|3252|F silent|TTG>TTA|L|3252 MDN1 MiDasiN 4910.0 0 0 0 0 -0.07467474022017151 Q12019 0.2877386212348938 0.08444532006978989 0.5202044844627379 48.909063086537174 40.0 0.0 no 8405 chrXII_354090r 23629 essential YLR106C 9626 + GCTTGCCGACACATATATCT L|3210|V L|3210|F A|3211|G A|3211|V MDN1 MiDasiN 4910.0 0 0 0 0 1.0560347362978917 Q12019 0.4475947916507721 0.02060900442302227 0.04198763892054558 0.02235481701791286 49.932857260391465 45.0 0.0 no 8406 chrXII_354439r 23632 essential YLR106C 9277 + GCGCTTATCATGAGCTGTCA A|3094|G A|3094|V S|3093|R silent|AGC>AGT|S|3093 MDN1 MiDasiN 4910.0 0 0 0 0 0.5140400314582297 Q12019 0.3307854533195496 0.5033749938011169 0.5226224660873413 53.448278136885904 50.0 0.0 no 8407 chrXII_354473 23633 essential YLR106C 9246 - TCTGCGCATGAAATATTGAT E|3089|Q E|3089|K A|3088|P A|3088|T MDN1 MiDasiN 4910.0 0 0 0 0 -0.3688400821756961 Q12019 0.5550041198730469 0.8999814391136169 0.28988367319107056 0.5702818632125854 41.16970152240839 35.0 0.0 no 8408 chrXII_354474 23634 essential YLR106C 9245 - CTGCGCATGAAATATTGATA A|3088|P A|3088|T C|3087|S C|3087|Y MDN1 MiDasiN 4910.0 0 0 0 0 0.15327516338410224 Q12019 0.28988367319107056 0.5702818632125854 1.0 0.038487955927848816 39.82034150793112 35.0 0.0 no 8409 chrXII_354803 23636 essential YLR106C 8916 - ATGCCTGTACGATATACCCT G|2978|A G|2978|D G|2978|R G|2978|S MDN1 MiDasiN 4910.0 0 0 0 0 -0.08689947019231586 Q12019 0.656524121761322 0.5441212058067322 0.5185422897338867 0.7453325390815735 51.782352198361814 45.0 0.0 no 8410 chrXII_354820r 23639 essential YLR106C 8896 + ACGACGCACCTCAATCCCCT D|2966|E silent|GAC>GAT|D|2966 D|2967|E silent|GAC>GAT|D|2967 MDN1 MiDasiN 4910.0 0 1 0 0 -0.1478490752284667 Q12019 1.0 1.0 58.10704890745001 60.0 0.0 no 8411 chrXII_354819r 23640 essential YLR106C 8897 + CGACGCACCTCAATCCCCTA D|2967|E silent|GAC>GAT|D|2967 A|2968|G A|2968|V MDN1 MiDasiN 4910.0 0 1 0 0 0.0054232617698525285 Q12019 1.0 0.4383711814880371 0.7770832777023315 57.193716120576994 60.0 0.0 no 8412 chrXII_354916r 23641 essential YLR106C 8800 + CTCAAAACCTAATGAAAAGT Q|2935|E Q|2935|* MDN1 MiDasiN 4910.0 0 1 0 0 0.3155686834716972 Q12019 1.0 33.68705979465477 30.0 0.0 no 8413 chrXII_354979 23642 essential YLR106C 8740 - ATCGTGTATTGCCGGATCAT D|2920|H D|2920|N MDN1 MiDasiN 4910.0 0 0 0 0 -1.132168552905212 Q12019 0.011140597984194756 0.16606490314006805 50.623870647327465 45.0 0.0 no 8414 chrXII_355059r 23646 essential YLR106C 8657 + TTCGAAATCATTAGAAGAAC S|2887|W S|2887|L MDN1 MiDasiN 4910.0 0 0 0 0 -0.19119642146134347 Q12019 0.008601658046245575 0.1331290602684021 32.84453050800937 30.0 0.0 no 8415 chrXII_355089r 23648 essential YLR106C 8627 + CATCTTTCCCGCTCTAGATT I|2877|M silent|ATC>ATT|I|2877 MDN1 MiDasiN 4910.0 0 0 0 0 1.0807786348591062 Q12019 0.18844297528266907 53.02387812319586 45.0 0.0 no 8416 chrXII_355537 23651 essential YLR106C 8182 - AGCAAGTTCTTTTATTAGCT A|2734|P A|2734|T MDN1 MiDasiN 4910.0 0 0 0 0 0.0673391037286572 Q12019 0.1862495094537735 0.2847900390625 43.785596848001546 30.0 0.0 no 8417 chrXII_355834 23653 essential YLR106C 7885 - TTCGAAAGCTAGCCAGCTGT E|2635|Q E|2635|K MDN1 MiDasiN 4910.0 0 0 0 0 0.7366639512424944 Q12019 0.6101592183113098 0.6419192552566528 51.63010497035879 50.0 0.0 no 8418 chrXII_355887r 23654 essential YLR106C 7829 + CCACTCCATAACTTTACTAT H|2611|Q silent|CAC>CAT|H|2611 H|2611|D H|2611|Y MDN1 MiDasiN 4910.0 0 0 0 0 -1.3658656087760597 Q12019 0.692852258682251 0.6354542970657349 0.9164588451385498 44.65022158800559 35.0 0.0 no 8419 chrXII_355888r 23655 essential YLR106C 7828 + GCCACTCCATAACTTTACTA H|2611|D H|2611|Y silent|GGC>GGG|G|2610 silent|GGC>GGT|G|2610 MDN1 MiDasiN 4910.0 0 0 0 0 -0.4854831623038486 Q12019 0.6354542970657349 0.9164588451385498 48.220875549037935 40.0 0.0 no 8420 chrXII_356091 23659 essential YLR106C 7628 - AATCCCAATAATATTGATAT D|2549|H D|2549|N W|2548|C W|2548|* MDN1 MiDasiN 4910.0 0 0 0 0 -0.4238705317800676 Q12019 0.0617378018796444 0.4461857080459595 0.1476849913597107 35.350465157902924 20.0 0.0 no 8421 chrXII_356209 23661 essential YLR106C 7510 - CTTCAAATGGCGACCGTTAA L|2509|F silent|TTG>TTA|L|2509 MDN1 MiDasiN 4910.0 0 0 0 0 -0.22451399196356286 Q12019 0.03944870457053185 45.18712138424171 45.0 0.0 no 8422 chrXII_356273r 23662 essential YLR106C 7443 + ATCAATGAAAAATCAACTCA I|2482|M silent|ATC>ATT|I|2482 MDN1 MiDasiN 4910.0 0 0 0 0 0.7689348719955045 Q12019 0.13661986589431765 31.97975323993899 25.0 0.0 no 8423 chrXII_356375 23663 essential YLR106C 7344 - TCTGAATACTTGCTGACTGT D|2455|H D|2455|N MDN1 MiDasiN 4910.0 0 0 0 0 -0.006722453707786569 Q12019 0.2646827697753906 0.2740783393383026 45.147794798796326 40.0 0.0 no 8424 chrXII_356433r 23664 essential YLR106C 7283 + GCATGATAAGCAATTGACAG H|2429|D H|2429|Y MDN1 MiDasiN 4910.0 0 0 0 0 -0.9997593310463474 Q12019 0.6092411875724792 0.033506352454423904 40.268785338860475 40.0 0.0 no 8425 chrXII_356468 23668 essential YLR106C 7251 - TTCTGGAATTTTAGGTTTGC Q|2423|H silent|CAG>CAA|Q|2423 MDN1 MiDasiN 4910.0 0 0 0 0 0.7238673706594173 Q12019 0.10544430464506148 43.70319838202977 35.0 0.0 no 8426 chrXII_356801r 23670 essential YLR106C 6915 + GACTTTGTTTCTATTGATGA D|2306|E silent|GAC>GAT|D|2306 MDN1 MiDasiN 4910.0 0 0 0 0 0.3322319760132713 Q12019 1.0 40.99067938614331 30.0 0.0 no 8427 chrXII_356830 23671 essential YLR106C 6889 - CTCTCCAAGTTCAAAGCCTA E|2303|Q E|2303|K G|2302|A G|2302|E MDN1 MiDasiN 4910.0 0 0 0 0 0.3575284434916955 Q12019 0.5871415138244629 0.8984261155128479 0.788192629814148 1.0 49.32138879321161 45.0 0.0 no 8428 chrXII_356834r 23672 essential YLR106C 6882 + CTCACCCTAGGCTTTGAACT silent|CTC>CTG|L|2295 silent|CTC>CTT|L|2295 T|2296|S T|2296|I MDN1 MiDasiN 4910.0 0 0 0 0 -0.074615485985629 Q12019 0.1850135326385498 0.7918915152549744 53.01400923726368 50.0 0.0 no 8429 chrXII_356846r 23674 essential YLR106C 6870 + GCCTTCGATCGCCTCACCCT silent|GCC>GCG|A|2291 silent|GCC>GCT|A|2291 A|2291|G A|2291|V MDN1 MiDasiN 4910.0 0 0 0 0 -0.02158884641501192 Q12019 0.367817759513855 0.2720670998096466 64.50945550791437 65.0 0.0 no 8430 chrXII_356829 23676 essential YLR106C 6890 - TCTCTCCAAGTTCAAAGCCT E|2303|Q E|2303|K E|2303|D silent|GAG>GAA|E|2303 MDN1 MiDasiN 4910.0 0 0 0 0 -0.4509738481630505 Q12019 0.5871415138244629 0.8984261155128479 0.555530309677124 50.95768293470468 45.0 0.0 no 8431 chrXII_356908 23677 essential YLR106C 6811 - ACCTCTGTTTCTCATAGCTC G|2277|R G|2277|S G|2277|A G|2277|D MDN1 MiDasiN 4910.0 0 0 0 0 -0.5729232720877858 Q12019 0.01660636998713016 0.287345826625824 0.20540548861026764 0.03282007947564125 53.10487427829611 45.0 0.0 no 8432 chrXII_356935 23678 essential YLR106C 6784 - TTCACCATATTTTGGATCCA E|2268|Q E|2268|K G|2267|A G|2267|D MDN1 MiDasiN 4910.0 0 1 0 0 0.07459183144534798 Q12019 0.0 0.0 0.0 0.0 47.322442097527635 35.0 0.0 no 8433 chrXII_356957 23679 essential YLR106C 6762 - GTCAAAAATAATCTGAAGTT L|2260|F silent|TTG>TTA|L|2260 MDN1 MiDasiN 4910.0 0 0 0 0 0.5329638457115498 Q12019 0.018441738560795784 32.08154389289137 25.0 0.0 no 8434 chrXII_356958 23680 essential YLR106C 6761 - TCAAAAATAATCTGAAGTTA L|2260|F silent|TTG>TTA|L|2260 MDN1 MiDasiN 4910.0 0 0 0 0 0.4036786721004752 Q12019 0.018441738560795784 29.51220316780899 20.0 0.0 no 8435 chrXII_357041r 23683 essential YLR106C 6675 + AACTCTCTATTGGAGATAGA N|2226|K silent|AAC>AAT|N|2226 S|2227|C S|2227|F MDN1 MiDasiN 4910.0 0 0 0 0 -1.5154143317055428 Q12019 0.0 0.0 0.0 40.724561872234524 35.0 0.0 no 8436 chrXII_357062 23684 essential YLR106C 6657 - TTCAGTCTATCAAGAACAGA silent|CTG>CTC|L|2225 silent|CTG>CTA|L|2225 R|2224|T R|2224|K MDN1 MiDasiN 4910.0 0 0 0 0 0.3830323945343677 Q12019 0.0 0.0 40.009206714690436 35.0 0.0 no 8437 chrXII_357171r 23686 essential YLR106C 6545 + AATCATCACTAAGGAAGCTT I|2183|M silent|ATC>ATT|I|2183 I|2184|M silent|ATC>ATT|I|2184 MDN1 MiDasiN 4910.0 0 0 0 0 0.9234944148432084 Q12019 0.14192348718643188 0.16091465950012207 40.49318934006021 35.0 0.0 no 8438 chrXII_357213 23687 essential YLR106C 6506 - TCATACTCATAGTTTTTAAT M|2175|I M|2175|I S|2174|T S|2174|N MDN1 MiDasiN 4910.0 0 0 0 0 -0.2550324630679219 Q12019 0.1789160668849945 0.1789160668849945 0.5696320533752441 0.4912988245487213 36.16559234736639 20.0 0.0 no 8439 chrXII_357215 23688 essential YLR106C 6504 - ATACTCATAGTTTTTAATAG S|2174|T S|2174|N M|2173|I M|2173|I MDN1 MiDasiN 4910.0 0 0 0 0 0.5986187555009874 Q12019 0.5696320533752441 0.4912988245487213 0.6897425055503845 0.6897425055503845 33.278861250404816 20.0 0.0 no 8440 chrXII_357334 23689 essential YLR106C 6385 - GTTCAAACCTTCCATGATTG L|2134|F silent|TTG>TTA|L|2134 MDN1 MiDasiN 4910.0 0 0 0 0 0.3578099318723738 Q12019 0.03433161973953247 45.201373580847594 40.0 0.0 no 8441 chrXII_357417r 23690 essential YLR106C 6299 + ACAAATATCATATATCACTG Q|2101|E Q|2101|* MDN1 MiDasiN 4910.0 0 0 0 0 -0.14633891073285776 Q12019 0.9953975677490234 33.5341615288869 25.0 0.0 no 8442 chrXII_357344 23691 essential YLR106C 6375 - TCCATGATTGCGGTAGCATT M|2131|I M|2131|I E|2132|Q E|2132|K MDN1 MiDasiN 4910.0 0 0 0 0 -0.4464082615474329 Q12019 0.2278718799352646 0.2278718799352646 0.6210178732872009 1.0 51.28716850521886 45.0 0.0 no 8443 chrXII_357450 23692 essential YLR106C 6269 - CAACTTGTTCATAACCACCA V|2096|L V|2096|I MDN1 MiDasiN 4910.0 0 0 0 0 0.039553322568101436 Q12019 0.06224429607391356 0.07654860615730286 45.67447394216464 40.0 0.0 no 8444 chrXII_357481 23693 essential YLR106C 6238 - ACTATCTATATCACTATTCA S|2086|T S|2086|N D|2085|H D|2085|N MDN1 MiDasiN 4910.0 0 0 0 0 -0.32991201997520153 Q12019 0.0 0.0 0.0 0.0 38.89342496852424 25.0 0.0 no 8445 chrXII_357544 23694 essential YLR106C 6175 - TCTTATCGTTTCCGTTTTAC R|2065|T R|2065|K silent|ACG>ACC|T|2063 silent|ACG>ACA|T|2063 MDN1 MiDasiN 4910.0 0 0 0 0 -0.3133262744089837 Q12019 0.041455604135990136 0.7711073160171509 46.28589051239658 35.0 0.0 no 8446 chrXII_357554 23695 essential YLR106C 6165 - TCCGTTTTACCGGAGTTTGA silent|ACG>ACC|T|2061 silent|ACG>ACA|T|2061 E|2062|Q E|2062|K MDN1 MiDasiN 4910.0 0 0 0 0 -1.2493533097858387 Q12019 0.5006679892539978 0.7791216373443604 51.24849146315972 45.0 0.0 no 8447 chrXII_357588r 23696 essential YLR106C 6128 + AATCAACAATAATTGGCCGT I|2044|M silent|ATC>ATT|I|2044 N|2045|K silent|AAC>AAT|N|2045 MDN1 MiDasiN 4910.0 0 0 0 0 0.4252194419882095 Q12019 0.01358211413025856 1.0 40.98356738002883 35.0 0.0 no 8448 chrXII_357613 23697 essential YLR106C 6106 - TTTCAAAACAGATTCATAAA L|2041|F silent|TTG>TTA|L|2041 MDN1 MiDasiN 4910.0 0 0 0 0 -0.5948460532253039 Q12019 0.4932345449924469 30.74962572382691 20.0 0.0 no 8449 chrXII_357632 23698 essential YLR106C 6087 - ACGGCGACATTGCACTCTAA V|2036|L V|2036|I A|2035|P A|2035|T MDN1 MiDasiN 4910.0 0 0 0 0 0.6807911437291787 Q12019 0.3223116099834442 0.8127303719520569 0.302276611328125 0.5121649503707886 49.01080249498682 50.0 0.0 no 8450 chrXII_357770r 23702 essential YLR106C 5946 + CTTCTCATTGAAGATATTTT L|1984|V L|1984|F silent|CTC>CTG|L|1984 silent|CTC>CTT|L|1984 MDN1 MiDasiN 4910.0 0 0 0 0 0.7838195242879691 Q12019 0.038851212710142136 0.0307028666138649 37.65788549397524 25.0 0.0 no 8451 chrXII_357867 23703 essential YLR106C 5852 - CATCTTCGCAAATCGAATAT D|1957|H D|1957|N E|1956|Q E|1956|K MDN1 MiDasiN 4910.0 0 0 0 0 1.0054820817447223 Q12019 0.109684519469738 0.6156036853790283 0.5971547961235046 0.9017619490623474 39.623529696617645 35.0 0.0 no 8452 chrXII_357917 23704 essential YLR106C 5802 - TCTCTCAAATTGAACTCCCA R|1940|T R|1940|K D|1941|H D|1941|N MDN1 MiDasiN 4910.0 0 0 0 0 -3.7500606255826754 Q12019 0.0 0.0 0.0 0.0 46.20021584631013 40.0 0.0 yes 8453 chrXII_357954r 23705 essential YLR106C 5762 + AGTCTGTAAAAGAAAACTTT silent|GTC>GTG|V|1922 silent|GTC>GTT|V|1922 MDN1 MiDasiN 4910.0 0 0 0 0 0.5029760461186098 Q12019 32.29519788120382 25.0 0.0 no 8454 chrXII_358103 23708 essential YLR106C 5616 - AATCGATTAACGAAAGATTT R|1878|P R|1878|Q MDN1 MiDasiN 4910.0 0 0 0 0 -4.087602903971101 Q12019 0.0 0.0 32.711810067649935 25.0 0.0 yes 8455 chrXII_358136 23711 essential YLR106C 5583 - CTACCACCACCTTGATACTG G|1867|A G|1867|D G|1867|R G|1867|S MDN1 MiDasiN 4910.0 0 0 0 0 0.6432630491578919 Q12019 0.0 0.0 0.0 0.0 50.633688073031685 50.0 0.0 no 8456 chrXII_358145r 23713 essential YLR106C 5571 + GCTCAAAATCCTCAGTATCA Q|1859|E Q|1859|* A|1858|G A|1858|V MDN1 MiDasiN 4910.0 0 0 0 0 0.34465476686244345 Q12019 0.0 0.0 0.0 45.69050382382596 40.0 0.0 no 8457 chrXII_358165 23714 essential YLR106C 5554 - AGCAGCAAAGACCAGAAAAT A|1858|P A|1858|T A|1857|P A|1857|T MDN1 MiDasiN 4910.0 0 0 0 0 -0.9759730049065324 Q12019 0.0 0.0 0.0 0.0 40.2775999346639 40.0 0.0 no 8458 chrXII_358245 23717 essential YLR106C 5474 - AACAGGCATTCAACCCTTCT C|1831|S C|1831|Y A|1830|P A|1830|T MDN1 MiDasiN 4910.0 0 0 0 0 0.031014125407357925 Q12019 0.0 0.0 0.0 0.0 50.70538893742657 45.0 0.0 no 8459 chrXII_358254 23719 essential YLR106C 5465 - TCAACCCTTCTAGGACGGAT L|1828|F silent|TTG>TTA|L|1828 silent|GGG>GGC|G|1827 silent|GGG>GGA|G|1827 MDN1 MiDasiN 4910.0 0 0 0 0 -0.6764613892669923 Q12019 0.0 51.08052915427032 50.0 0.0 no 8460 chrXII_358258r 23721 essential YLR106C 5458 + CCTCCCAATCCGTCCTAGAA S|1821|C S|1821|F silent|GCC>GCG|A|1820 silent|GCC>GCT|A|1820 MDN1 MiDasiN 4910.0 0 0 0 0 -0.01300192121800961 Q12019 0.0 0.0 56.59827376567757 55.00000000000001 0.0 no 8461 chrXII_358259r 23722 essential YLR106C 5457 + GCCTCCCAATCCGTCCTAGA silent|GCC>GCG|A|1820 silent|GCC>GCT|A|1820 A|1820|G A|1820|V MDN1 MiDasiN 4910.0 0 0 0 0 -0.0016143820193731118 Q12019 0.0 0.0 61.91203422436968 60.0 0.0 no 8462 chrXII_358316 23723 essential YLR106C 5403 - TTCTTCATTGCTCTTAAAAA K|1807|N silent|AAG>AAA|K|1807 M|1806|I M|1806|I MDN1 MiDasiN 4910.0 0 0 0 0 0.4064121406046215 Q12019 0.014918113127350809 0.0 0.0 37.211808951155774 25.0 0.0 no 8463 chrXII_358407r 23726 essential YLR106C 5309 + AATCAATTTGTCTGAACAAA I|1771|M silent|ATC>ATT|I|1771 MDN1 MiDasiN 4910.0 0 0 0 0 -0.21217713897280926 Q12019 0.0 33.61814027811965 25.0 0.0 no 8464 chrXII_358435 23727 essential YLR106C 5284 - AAGCTTATTTCCTGTAATAT K|1767|N silent|AAG>AAA|K|1767 MDN1 MiDasiN 4910.0 0 0 0 0 0.2415505500654888 Q12019 0.4911286234855652 39.986386235367604 25.0 0.0 no 8465 chrXII_358499r 23730 essential YLR106C 5217 + CACAAGCCAATTTTACTTGA H|1740|Q silent|CAC>CAT|H|1740 P|1742|A P|1742|S MDN1 MiDasiN 4910.0 0 0 0 0 0.31693973491991745 Q12019 0.4054107069969177 0.0 0.0 42.2161556531026 35.0 0.0 no 8466 chrXII_358533r 23731 essential YLR106C 5183 + AAACTTAGTAAGGGTTGTAC N|1729|K silent|AAC>AAT|N|1729 MDN1 MiDasiN 4910.0 0 0 0 0 0.9880234968524516 Q12019 0.0 38.60825524554582 35.0 0.0 no 8467 chrXII_358543r 23732 essential YLR106C 5173 + CTACTGCCTCAAACTTAGTA T|1726|S T|1726|I A|1727|G A|1727|V MDN1 MiDasiN 4910.0 0 0 0 0 1.2318760182106787 Q12019 0.0 0.0 0.03725159540772438 0.10328923165798187 45.322167864824216 40.0 0.0 no 8468 chrXII_358537 23735 essential YLR106C 5182 - TACAACCCTTACTAAGTTTG V|1734|L V|1734|I V|1733|L V|1733|I MDN1 MiDasiN 4910.0 0 0 0 0 0.9766313805080388 Q12019 0.3800373375415802 0.7758188843727112 0.0 0.0 41.98277380647818 35.0 0.0 no 8469 chrXII_358770 23737 essential YLR106C 4949 - AAGCAGTGTTATTTGTACCA A|1656|P A|1656|T MDN1 MiDasiN 4910.0 0 0 0 0 1.029422690644229 Q12019 0.013440202921628952 0.012312783859670162 45.66976750622979 35.0 0.0 no 8470 chrXII_358771 23738 essential YLR106C 4948 - AGCAGTGTTATTTGTACCAA A|1656|P A|1656|T MDN1 MiDasiN 4910.0 0 0 0 0 0.3036518667411793 Q12019 0.013440202921628952 0.012312783859670162 45.66976750622979 35.0 0.0 no 8471 chrXII_358644r 23739 essential YLR106C 5072 + GAACGAAATTATTGTGACTC N|1692|K silent|AAC>AAT|N|1692 MDN1 MiDasiN 4910.0 0 0 0 0 0.8211656923817384 Q12019 0.3260234296321869 36.28823284938585 35.0 0.0 no 8472 chrXII_359023 23741 essential YLR106C 4696 - TACATCGTTGAAATCTTCCA V|1572|L V|1572|I D|1571|H D|1571|N MDN1 MiDasiN 4910.0 0 0 0 0 0.5504001124283853 Q12019 0.032432939857244485 0.15213720500469208 0.0 0.0 42.86454043153384 35.0 0.0 no 8473 chrXII_359111r 23742 essential YLR106C 4605 + TTCGCAACCATGAACCCTGG F|1536|L silent|TTC>TTT|F|1536 A|1537|G A|1537|V MDN1 MiDasiN 4910.0 0 0 0 0 0.9139043376960916 Q12019 1.0 0.0 0.0 51.82996432584496 55.00000000000001 0.0 no 8474 chrXII_359114r 23743 essential YLR106C 4602 + TTCTTCGCAACCATGAACCC F|1535|L silent|TTC>TTT|F|1535 F|1536|L silent|TTC>TTT|F|1536 MDN1 MiDasiN 4910.0 0 0 0 0 -1.4152605659644129 Q12019 0.0 1.0 50.96925033157754 50.0 0.0 no 8475 chrXII_359186 23744 essential YLR106C 4533 - GCTAACAACAAACTCCTTTC A|1518|P A|1518|T L|1516|F silent|TTG>TTA|L|1516 MDN1 MiDasiN 4910.0 0 0 0 0 -0.07260357421249578 Q12019 0.013313449919223784 0.0955287590622902 0.0 42.1509574694095 40.0 0.0 no 8476 chrXII_359218 23745 essential YLR106C 4501 - ACTATTTAGTCTTTCAAGAA S|1507|T S|1507|N MDN1 MiDasiN 4910.0 0 0 0 0 -0.0039803365206592676 Q12019 0.0 0.0 37.06528124265958 25.0 0.0 no 8477 chrXII_359343r 23747 essential YLR106C 4373 + ACTGGAAATACAAAAGCTGA L|1459|V silent|CTG>TTG|L|1459 MDN1 MiDasiN 4910.0 0 0 0 0 0.9190932539023592 Q12019 0.2739839851856232 36.35865659204262 35.0 0.0 no 8478 chrXII_359344r 23748 essential YLR106C 4372 + AACTGGAAATACAAAAGCTG L|1459|V silent|CTG>TTG|L|1459 MDN1 MiDasiN 4910.0 0 0 0 0 -0.0981819662186843 Q12019 0.2739839851856232 34.15535327875551 35.0 0.0 no 8479 chrXII_359418 23749 essential YLR106C 4301 - ACTCTTTCAAGTCTACATCT E|1440|Q E|1440|K E|1440|D silent|GAG>GAA|E|1440 MDN1 MiDasiN 4910.0 0 0 0 0 -0.14281137223075646 Q12019 0.3582882285118103 0.5584573745727539 0.5661331415176392 45.018941443201015 35.0 0.0 no 8480 chrXII_359500r 23750 essential YLR106C 4216 + CTCAAAGACCTGTTCGTAAC Q|1407|E Q|1407|* MDN1 MiDasiN 4910.0 0 0 0 0 0.7839167426973229 Q12019 0.0 43.61391941921971 45.0 0.0 no 8481 chrXII_359536 23751 essential YLR106C 4183 - TCCAGTTTCTGTGTTTTGAT G|1401|R G|1401|R G|1401|A G|1401|E MDN1 MiDasiN 4910.0 0 0 0 0 0.3885244844480888 Q12019 0.005107465200126171 0.005107465200126171 0.04862774908542633 0.007531190756708381 48.66101140881825 35.0 0.0 no 8482 chrXII_359583r 23753 essential YLR106C 4133 + CCAATTATTGGCGCAATTCA Q|1379|E Q|1379|* MDN1 MiDasiN 4910.0 0 0 0 0 0.9554666806493752 Q12019 0.07207410037517548 45.96179063730103 40.0 0.0 no 8483 chrXII_359595r 23754 essential YLR106C 4121 + AACAACAATTTGCCAATTAT T|1375|R T|1375|I T|1376|R T|1376|I MDN1 MiDasiN 4910.0 0 0 0 0 -2.045016314075732 Q12019 0.0 0.0 0.003850607201457024 0.004305377136915922 36.64245552194621 25.0 0.0 yes 8484 chrXII_359707 23759 essential YLR106C 4012 - TGTCCAAGTAACAGAGCCAA W|1343|C W|1343|* W|1343|S W|1343|* MDN1 MiDasiN 4910.0 0 0 0 0 -1.1807203686790513 Q12019 0.0 0.0 47.15818375718885 45.0 0.0 no 8485 chrXII_359892 23763 essential YLR106C 3827 - CTGCGTCCCTTAAAGCCCAG A|1282|P A|1282|T D|1281|H D|1281|N MDN1 MiDasiN 4910.0 0 0 0 0 0.12542473703445794 Q12019 0.0 0.0 0.028462192043662068 0.0942692831158638 57.23495630716889 60.0 0.0 no 8486 chrXII_359898r 23764 essential YLR106C 3818 + TCTTTTCCGCTGGGCTTTAA L|1274|V L|1274|F F|1275|L silent|TTC>TTT|F|1275 MDN1 MiDasiN 4910.0 0 0 0 0 0.8980628846074 Q12019 0.0 0.0 0.0 52.97210825000685 45.0 0.0 no 8487 chrXII_359899r 23765 essential YLR106C 3817 + ATCTTTTCCGCTGGGCTTTA L|1274|V L|1274|F MDN1 MiDasiN 4910.0 0 0 0 0 1.1783338568550696 Q12019 0.0 0.0 54.72234424385971 45.0 0.0 no 8488 chrXII_359908r 23766 essential YLR106C 3808 + CTCTACGTGATCTTTTCCGC L|1271|V silent|CTA>TTA|L|1271 R|1272|G R|1272|C MDN1 MiDasiN 4910.0 0 0 0 0 -0.9352846926332572 Q12019 0.0 0.0 0.0 51.959577000711526 50.0 0.0 no 8489 chrXII_359907r 23767 essential YLR106C 3809 + TCTACGTGATCTTTTCCGCT L|1271|V silent|CTA>TTA|L|1271 R|1272|G R|1272|C MDN1 MiDasiN 4910.0 0 0 0 0 -1.2623269096843286 Q12019 0.0 0.0 0.0 51.959577000711526 45.0 0.0 no 8490 chrXII_360002 23770 essential YLR106C 3717 - ACGATTTTCTTTGCATATGA V|1246|L V|1246|I MDN1 MiDasiN 4910.0 0 0 0 0 -0.1092403235121648 Q12019 0.0 0.0 41.84908680498648 30.0 0.0 no 8491 chrXII_360128 23773 essential YLR106C 3591 - TTACGGCCACCGTATATCCC R|1203|P R|1203|H G|1202|A G|1202|D MDN1 MiDasiN 4910.0 0 0 0 0 -3.805674648100279 Q12019 0.0 0.0 0.0 0.0 56.25061247896531 55.00000000000001 0.0 yes 8492 chrXII_360145r 23776 essential YLR106C 3571 + TTGCTACCCAGAATCCACCT A|1192|G A|1192|V T|1193|S T|1193|I MDN1 MiDasiN 4910.0 0 0 0 0 -0.5900100216056022 Q12019 0.0 0.0 0.0 0.0 55.18327382272104 50.0 0.0 no 8493 chrXII_360232 23777 essential YLR106C 3487 - ATCGTCAAGTAACCTATTTA D|1169|H D|1169|N D|1168|H D|1168|N MDN1 MiDasiN 4910.0 0 0 0 0 -2.8677604344878875 Q12019 0.0 0.0 0.0 0.0 40.84100765999528 30.0 0.0 yes 8494 chrXII_360356r 23778 essential YLR106C 3360 + ACATATGTTACCGATGATAC T|1121|R T|1121|I MDN1 MiDasiN 4910.0 0 0 0 0 -0.08595594047346093 Q12019 0.003850607201457024 0.004305377136915922 40.64294326849751 35.0 0.0 no 8495 chrXII_360390 23780 essential YLR106C 3329 - CCTGTAAATCTGTATGCTCA Q|1116|H silent|CAG>CAA|Q|1116 MDN1 MiDasiN 4910.0 0 0 0 0 0.30225345918393165 Q12019 0.0 46.34092350509411 40.0 0.0 no 8496 chrXII_360390r 23781 essential YLR106C 3326 + CCATGAGCATACAGATTTAC H|1110|D H|1110|Y MDN1 MiDasiN 4910.0 0 0 0 0 0.16669196975956044 Q12019 0.0 0.0 43.50074738553678 40.0 0.0 no 8497 chrXII_360476r 23783 essential YLR106C 3240 + ATTCAAGGTCCAACTTCATC Q|1082|E Q|1082|* MDN1 MiDasiN 4910.0 0 0 0 0 0.06290455569634511 Q12019 0.0 45.68758485840249 40.0 0.0 no 8498 chrXII_360581 23785 essential YLR106C 3138 - GCTTGTTCTTGAATTGTATT A|1053|P A|1053|T MDN1 MiDasiN 4910.0 0 0 0 0 -0.3678484850806566 Q12019 1.0 0.16146963834762573 42.86605095413489 30.0 0.0 no 8499 chrXII_360635 23787 essential YLR106C 3084 - ACATAATCTGGTCCTGGAGA V|1035|L V|1035|I MDN1 MiDasiN 4910.0 0 0 0 0 0.3606726867753634 Q12019 0.030258156359195713 0.24678154289722445 48.19711493316645 45.0 0.0 no 8500 chrXII_360647r 23789 essential YLR106C 3069 + TCACAGACACCTCCCTCTCC Q|1025|E Q|1025|* S|1024|* S|1024|L MDN1 MiDasiN 4910.0 0 1 0 0 -1.0951768837185505 Q12019 0.02583031915128231 0.01104907039552927 60.641659828128574 60.0 0.0 no 8501 chrXII_360768 23791 essential YLR106C 2951 - TCATACAGAATCCATCATAC M|990|I M|990|I C|989|S C|989|Y MDN1 MiDasiN 4910.0 0 0 0 0 -0.4460018059485441 Q12019 0.0 0.0 0.29412391781806946 0.005366934929043055 40.814270146273536 35.0 0.0 no 8502 chrXII_360779r 23792 essential YLR106C 2937 + CTACGCCGTTCCCTGTATGA R|981|G R|981|C silent|CGC>CGG|R|981 silent|CGC>CGT|R|981 MDN1 MiDasiN 4910.0 0 0 0 0 -0.34763697741186744 Q12019 0.0 0.0 56.551958412373494 55.00000000000001 0.0 no 8503 chrXII_360803r 23793 essential YLR106C 2913 + ACTGATATTATTCATATCTA T|972|S T|972|I MDN1 MiDasiN 4910.0 0 0 0 0 0.22374782054548004 Q12019 0.7603957653045654 0.1371801346540451 35.76360634051798 20.0 0.0 no 8504 chrXII_361276r 23798 essential YLR106C 2440 + GTTCTTTGGTAAAGACTATC S|815|C S|815|F MDN1 MiDasiN 4910.0 0 0 0 0 0.9520875664656834 Q12019 0.004648099187761545 0.002179444767534733 40.397492931414384 35.0 0.0 no 8505 chrXII_361567 23800 essential YLR106C 2152 - AAACTTCTCGTTCTTCTTTA K|723|N silent|AAG>AAA|K|723 E|722|D silent|GAG>GAA|E|722 MDN1 MiDasiN 4910.0 0 0 0 0 0.16268643253120954 Q12019 0.025240631774067882 0.3995682001113892 42.28597988113557 30.0 0.0 no 8506 chrXII_361636 23801 essential YLR106C 2083 - TGCAACTGTTTTAGAATTTA A|701|P A|701|T V|700|L V|700|I MDN1 MiDasiN 4910.0 0 0 0 0 0.23052084138413395 Q12019 0.0 0.0 0.39413169026374817 1.0 37.42803774787376 25.0 0.0 no 8507 chrXII_361637 23802 essential YLR106C 2082 - GCAACTGTTTTAGAATTTAC A|701|P A|701|T V|700|L V|700|I MDN1 MiDasiN 4910.0 0 0 0 0 -0.004125781570209708 Q12019 0.0 0.0 0.39413169026374817 1.0 37.81793386159006 30.0 0.0 no 8508 chrXII_361897 23806 essential YLR106C 1822 - TAGCTTTTCCTTAAGTAATA K|613|N silent|AAG>AAA|K|613 MDN1 MiDasiN 4910.0 0 0 0 0 0.7979992072135675 Q12019 0.4734850823879242 39.685049405641344 25.0 0.0 no 8509 chrXII_361939 23807 essential YLR106C 1780 - ATCATCAAGGTTTTCCAAAG D|600|H D|600|N D|599|H D|599|N MDN1 MiDasiN 4910.0 0 0 0 0 0.5912057217992359 Q12019 0.20574435591697693 0.5208221673965454 0.03606758266687393 0.13783127069473267 41.26017593563376 35.0 0.0 no 8510 chrXII_361940 23808 essential YLR106C 1779 - TCATCAAGGTTTTCCAAAGT D|600|H D|600|N D|599|H D|599|N MDN1 MiDasiN 4910.0 0 0 0 0 0.20177215172809515 Q12019 0.20574435591697693 0.5208221673965454 0.03606758266687393 0.13783127069473267 43.731730647179525 35.0 0.0 no 8511 chrXII_361950 23809 essential YLR106C 1769 - TTTCCAAAGTGGGCACATGT E|596|Q E|596|K L|595|F silent|TTG>TTA|L|595 MDN1 MiDasiN 4910.0 0 0 0 0 -0.7560158911615584 Q12019 0.3576929271221161 0.4146417677402496 1.0 49.40887637220567 45.0 0.0 no 8512 chrXII_362057r 23810 essential YLR106C 1659 + GACTGTTTCGCTGGCGCTAT D|554|E silent|GAC>GAT|D|554 MDN1 MiDasiN 4910.0 0 0 0 0 -0.2017095665256588 Q12019 0.11983021348714827 55.50745002659925 55.00000000000001 0.0 no 8513 chrXII_362220r 23814 essential YLR106C 1496 + GTTCATTTCATTGAACAAGG F|500|L silent|TTC>TTT|F|500 MDN1 MiDasiN 4910.0 0 0 0 0 -0.7680588508672093 Q12019 0.0 39.741443030516855 35.0 0.0 no 8514 chrXII_362280 23815 essential YLR106C 1439 - AATCGATTAGTTTGGGGATA D|486|H D|486|N MDN1 MiDasiN 4910.0 0 0 0 0 -0.9181159420331044 Q12019 0.08643294870853424 0.41841980814933777 41.8093057548665 35.0 0.0 no 8515 chrXII_362393r 23816 essential YLR106C 1323 + ATCTATAACTTGAATATGAT I|442|M silent|ATC>ATT|I|442 MDN1 MiDasiN 4910.0 0 0 0 0 0.4610565335838939 Q12019 0.1234130635857582 32.619809750207764 20.0 0.0 no 8516 chrXII_362451 23817 essential YLR106C 1268 - TTCTAACAGTTGATATTAAC R|429|T R|429|K V|428|L V|428|I MDN1 MiDasiN 4910.0 0 0 0 0 0.11466414652826815 Q12019 0.4067753851413727 0.2807111740112305 0.1952851116657257 1.0 34.053487557129586 25.0 0.0 no 8517 chrXII_362501r 23820 essential YLR106C 1215 + GAACTAACCATTCCATCCAG L|407|V silent|CTA>TTA|L|407 MDN1 MiDasiN 4910.0 0 0 0 0 0.4879175065678988 Q12019 0.01996077224612236 47.12671528224308 45.0 0.0 no 8518 chrXII_362596 23822 essential YLR106C 1123 - CCATCTCCCTTCTTTGACCG W|381|S W|381|* R|380|T R|380|K MDN1 MiDasiN 4910.0 0 0 0 0 -0.5595069129343655 Q12019 0.0 0.02425829693675041 1.0 57.31601512061928 55.00000000000001 0.0 no 8519 chrXII_362707 23828 essential YLR106C 1012 - ACCTAAATGAATTTTCACAA G|344|R G|344|S G|344|A G|344|D MDN1 MiDasiN 4910.0 0 0 0 0 0.2756629910178013 Q12019 0.012415485456585884 0.04570131748914719 0.025631330907344815 0.0755477100610733 35.64999821389074 25.0 0.0 no 8520 chrXII_362678r 23829 essential YLR106C 1038 + ACTGATGCCAAGTTACTGAT T|347|S T|347|I MDN1 MiDasiN 4910.0 0 0 0 0 0.9905514054986368 Q12019 0.0 0.0 45.71870041333625 40.0 0.0 no 8521 chrXII_362789 23831 essential YLR106C 930 - GCTTTTCCAATGAGCATTAT A|317|P A|317|T G|315|A G|315|E MDN1 MiDasiN 4910.0 0 0 0 0 -0.4442501718025992 Q12019 0.14918720722198486 0.21870845556259155 0.0 0.0 46.02111229353478 35.0 0.0 no 8522 chrXII_362833r 23833 essential YLR106C 883 + TTTCCTCTCTTCGTCAACTC S|296|C S|296|F silent|TCC>TCG|S|296 silent|TCC>TCT|S|296 MDN1 MiDasiN 4910.0 0 0 0 0 0.8478962987756447 Q12019 0.04324239492416382 0.040681973099708564 51.41922280184378 45.0 0.0 no 8523 chrXII_362948 23838 essential YLR106C 771 - ACCTTAGTACTCAAATCCTG K|263|N silent|AAG>AAA|K|263 V|264|L V|264|I MDN1 MiDasiN 4910.0 0 0 0 0 -0.31222047446467754 Q12019 0.6030623912811279 0.03980598598718643 0.4670173525810242 45.22236814036523 40.0 0.0 no 8524 chrXII_362964r 23839 essential YLR106C 752 + CTACTTCATTATTGAGCCTC Y|252|* silent|TAC>TAT|Y|252 F|253|L silent|TTC>TTT|F|253 MDN1 MiDasiN 4910.0 0 0 0 0 0.8307286210791657 Q12019 0.3985856473445892 46.94567226258317 40.0 0.0 no 8525 chrXII_363051 23841 essential YLR106C 668 - TCTTAGCTTCGTTCAGTTCG K|229|N silent|AAG>AAA|K|229 A|228|P A|228|T MDN1 MiDasiN 4910.0 0 0 0 0 0.2952406337629824 Q12019 0.28570881485939026 0.015303388237953188 0.01483476534485817 50.24662304951102 45.0 0.0 no 8526 chrXII_363249r 23843 essential YLR106C 467 + CGACATTTTATACCAACTTG D|157|E silent|GAC>GAT|D|157 MDN1 MiDasiN 4910.0 0 0 0 0 0.6934582687253376 Q12019 1.0 40.08291383599283 35.0 0.0 no 8527 chrXII_363250 23845 essential YLR106C 469 - CACAAGTTGGTATAAAATGT V|163|L V|163|M MDN1 MiDasiN 4910.0 0 0 0 0 -0.4906120018163337 Q12019 1.0 0.1815585196018219 35.79496027232425 30.0 0.0 no 8528 chrXII_363347 23846 essential YLR106C 372 - TCGGAATCCTTTTGTGTGGA D|131|H D|131|N MDN1 MiDasiN 4910.0 0 0 0 0 0.1090449612219675 Q12019 0.0254622045904398 0.07327641546726227 49.560113539210526 45.0 0.0 no 8529 chrXII_363354r 23847 essential YLR106C 362 + TCAAAATCCATCCACACAAA Q|122|E Q|122|* MDN1 MiDasiN 4910.0 0 0 0 0 0.49079732379144403 Q12019 1.0 40.306035275602206 35.0 0.0 no 8530 chrXII_363419 23848 essential YLR106C 300 - TCAATTAATGGCATTGCAAC E|107|Q E|107|K MDN1 MiDasiN 4910.0 0 0 0 0 1.2988285979851837 Q12019 0.11710824817419052 0.09937022626399994 39.950480567210825 35.0 0.0 no 8531 chrXII_363560r 23850 essential YLR106C 156 + CTACATAGCCGTTCCATCAC H|54|D H|54|Y MDN1 MiDasiN 4910.0 0 0 0 0 0.14781572243049215 Q12019 0.6958870887756348 0.4947828948497772 52.040857578238565 50.0 0.0 no 8532 chrXII_363643 23852 essential YLR106C 76 - GGGCGCTTCAATAGCATCAG silent|GCG>GCC|A|31 silent|GCG>GCA|A|31 A|31|P A|31|T MDN1 MiDasiN 4910.0 0 0 0 0 -0.7927015636272731 Q12019 0.2049916535615921 0.4065556526184082 52.20962705373455 55.00000000000001 0.0 no 8533 chrXII_378025r 23853 essential YLR115W 43 - TCGTACCACTGAACCAACGG R|21|P R|21|Q V|20|L V|20|I CFT2 Cleavage Factor Two 859.0 0 0 0 0 0.4326063980492191 Q12102 0.9099509716033936 0.949662983417511 0.9539830088615416 0.9574310183525084 0.03650124371051788 0.0946381613612175 1.0 0.1766626536846161 4.1305999755859375 1.6676000356674194 0.16660000383853912 -1.2007999420166016 48.56554032740154 55.00000000000001 1.0 no 8534 chrXII_378061 23855 essential YLR115W 76 + CCTTGTTAATCGATCCCGGT silent|ACC>ACG|T|26 silent|ACC>ACT|T|26 CFT2 Cleavage Factor Two 859.0 0 0 0 0 0.20117797165924373 Q12102 53.3852679955146 50.0 1.0 no 8535 chrXII_378168r 23860 essential YLR115W 186 - GCACCTAAACATTCAATTGT G|68|A G|68|D A|69|P A|69|T CFT2 Cleavage Factor Two 859.0 0 0 0 0 -1.2394408449921437 Q12102 0.9499930143356324 0.9446240067481996 0.9573720097541808 0.9523990154266356 0.0 0.0 0.034220993518829346 0.033140115439891815 5.1040000915527335 14.871999740600586 10.914999961853027 3.79040002822876 42.3920742581214 35.0 1.0 no 8536 chrXII_378253 23861 essential YLR115W 268 + CTCTTCCTGTTATCAACTTA L|91|V L|91|F P|92|A P|92|S CFT2 Cleavage Factor Two 859.0 0 0 0 0 -0.3699555381428194 Q12102 0.9512209892272948 0.9587849974632264 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 0.5483999848365784 0.1809999942779541 2.7767999172210693 4.6946001052856445 45.773620967165925 35.0 1.0 no 8537 chrXII_378252 23864 essential YLR115W 267 + ACTCTTCCTGTTATCAACTT L|91|V L|91|F T|90|S T|90|I CFT2 Cleavage Factor Two 859.0 0 0 0 0 0.1753958548335583 Q12102 0.9512209892272948 0.9587849974632264 0.9491789937019348 0.9472420215606691 0.0 0.0 0.0 0.0 0.5483999848365784 0.1809999942779541 0.8704000115394592 1.1749999523162842 46.822270576840474 35.0 1.0 no 8538 chrXII_378380 23865 essential YLR115W 395 + ACCTTTGAAGTACTCGCAAT P|133|R P|133|L P|133|A P|133|S CFT2 Cleavage Factor Two 859.0 0 0 0 0 0.4358414326588557 Q12102 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.07631434500217438 0.1595243662595749 0.3048766255378723 0.5940122604370117 0.2752000093460083 0.5192000269889832 1.1344000101089478 1.9600000381469729 45.44620394090345 40.0 1.0 no 8539 chrXII_378381r 23866 essential YLR115W 399 - ACCAATTGCGAGTACTTCAA L|139|F silent|TTG>TTA|L|139 V|140|L V|140|I CFT2 Cleavage Factor Two 859.0 0 0 0 0 -1.3084147563276531 Q12102 0.9587849974632264 0.9539830088615416 0.9574310183525084 0.114760659635067 0.3033227622509003 0.4404805600643158 0.9187999963760376 -0.6204000115394592 -0.7006000280380249 44.961573024421625 40.0 1.0 no 8540 chrXII_378432 23867 essential YLR115W 447 + ACTTTACTGGCGTACAATGC T|150|S T|150|I L|152|V silent|CTG>TTG|L|152 CFT2 Cleavage Factor Two 859.0 0 0 0 0 0.4100345835785753 Q12102 0.9491789937019348 0.9472420215606691 0.9512209892272948 1.0 0.012289004400372505 1.0 0.7342000007629395 -0.6366000175476074 0.8217999935150146 46.80104083302905 45.0 1.0 no 8541 chrXII_378485 23870 essential YLR115W 500 + TAGCACATACTCAGAGAAAT S|168|R silent|AGC>AGT|S|168 T|169|R T|169|I CFT2 Cleavage Factor Two 859.0 0 0 0 0 -0.020519624928967858 Q12102 0.9417110085487366 0.9476869702339172 0.9472420215606691 0.12869520485401156 0.017973164096474648 0.012069983407855034 0.35920000076293945 1.0255999565124512 0.33219999074935913 39.031884393100654 35.0 1.0 no 8542 chrXII_378555 23872 essential YLR115W 570 + GCTTCTATATTGGACGCCAC A|191|G A|191|V S|192|C S|192|F CFT2 Cleavage Factor Two 859.0 0 0 0 0 0.6737020502674824 Q12102 0.9484469890594482 0.9504740238189696 0.945252001285553 0.9294660091400146 0.03997508436441422 0.013450395315885544 0.06295674294233322 0.0560782365500927 1.7139999866485596 0.8148000240325928 -0.09539999812841417 -0.9718000292778016 51.33883985732354 50.0 1.0 no 8543 chrXII_378583r 23873 essential YLR115W 601 - GGGCCTCATCAAAGTTGATA R|206|S silent|AGG>AGA|R|206 R|206|T R|206|K CFT2 Cleavage Factor Two 859.0 0 0 0 0 -0.08959635830512633 Q12102 0.9087679982185364 0.932735025882721 0.955805003643036 0.020586192607879642 0.026198964565992355 0.5280385017395021 0.5866000056266785 0.3903999924659729 -0.30180001258850103 48.35959970377758 45.0 1.0 no 8544 chrXII_378859 23876 essential YLR115W 874 + ATGCCAAATCAATGCTCGAG A|293|G A|293|V silent|GCC>GCG|A|293 silent|GCC>GCT|A|293 CFT2 Cleavage Factor Two 859.0 0 0 0 0 -0.4898493097507983 Q12102 0.9484469890594482 0.9504740238189696 0.0336051769554615 0.027661221101880074 2.3469998836517334 4.941599845886231 44.68653415114119 45.0 1.0 no 8545 chrXII_378862r 23877 essential YLR115W 880 - CAGCCACTCGAGCATTGATT W|299|C W|299|* W|299|S W|299|* CFT2 Cleavage Factor Two 859.0 0 0 0 0 -0.3812096637651771 Q12102 0.8858469724655151 0.8858469724655151 0.0 0.0 3.240400075912476 3.8155999183654794 51.66951284936818 50.0 1.0 no 8546 chrXII_379072r 23882 essential YLR115W 1090 - GCTCGGCTTGGTCAAAATCA silent|CCG>CCC|P|369 silent|CCG>CCA|P|369 S|370|T S|370|N CFT2 Cleavage Factor Two 859.0 0 0 0 0 -1.5262301971427237 Q12102 0.9512869715690612 0.9536849856376648 0.7259407639503479 0.6705940961837769 0.34139999747276306 1.0346000194549558 49.79546540349629 50.0 1.0 no 8547 chrXII_379089r 23883 essential YLR115W 1107 - GACGACGCACATTCAAAGCT silent|TCG>TCC|S|375 silent|TCG>TCA|S|375 silent|GCG>GCC|A|374 silent|GCG>GCA|A|374 CFT2 Cleavage Factor Two 859.0 0 0 0 0 -0.9632357178046616 Q12102 46.56187881855112 50.0 1.0 no 8548 chrXII_379216r 23884 essential YLR115W 1234 - ACTCAAGGGTTCTTCTTTTA L|417|F silent|TTG>TTA|L|417 S|418|T S|418|N CFT2 Cleavage Factor Two 859.0 0 0 0 0 -0.05529327464338982 Q12102 0.9587849974632264 0.9512869715690612 0.9536849856376648 0.0 0.6033712029457092 0.5519608855247498 0.4025999903678894 -0.11559999734163286 -0.3328000009059906 46.122652028607995 35.0 1.0 no 8549 chrXII_379231r 23885 essential YLR115W 1249 - CTCTGTTTCCTCTTTACTCA E|423|Q E|423|K CFT2 Cleavage Factor Two 859.0 0 0 0 0 0.7169502265883771 Q12102 0.956179976463318 0.9475290179252625 0.37381574511528015 0.5307046175003052 51.480036944385745 40.0 1.0 no 8550 chrXII_379363r 23887 essential YLR115W 1381 - TCTCATTGCCCTCTCTCCGT M|466|I M|466|I R|467|T R|467|K CFT2 Cleavage Factor Two 859.0 0 0 0 0 -0.16303700734934967 Q12102 0.9553959965705872 0.9553959965705872 0.932735025882721 0.955805003643036 0.5085670948028564 0.5085670948028564 0.5738092064857483 0.9218620061874391 62.402392239797905 55.00000000000001 1.0 no 8551 chrXII_379422 23888 essential YLR115W 1437 + CCACCGATTGATCATATTAT P|481|A P|481|S P|480|R P|480|L CFT2 Cleavage Factor Two 859.0 0 0 0 0 -0.896542528110341 Q12102 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.7485865950584412 0.717967689037323 0.4572264850139618 0.28973957896232605 44.04567256980175 35.0 1.0 no 8552 chrXII_379424 23890 essential YLR115W 1439 + ACCGATTGATCATATTATGG P|481|R P|481|L P|481|A P|481|S CFT2 Cleavage Factor Two 859.0 0 0 0 0 1.2142248875529729 Q12102 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.5160564184188843 0.328823059797287 0.7485865950584412 0.717967689037323 41.405636488002585 35.0 1.0 no 8553 chrXII_379604r 23893 essential YLR115W 1622 - CATCTTTCTTGATTTTAGCG D|547|H D|547|N CFT2 Cleavage Factor Two 859.0 0 0 0 0 0.043916906087948036 Q12102 0.9486550092697144 0.956179976463318 0.0 0.0 43.26973820019106 35.0 1.0 no 8554 chrXII_379606r 23894 essential YLR115W 1624 - ATCATCTTTCTTGATTTTAG D|548|H D|548|N D|547|H D|547|N CFT2 Cleavage Factor Two 859.0 0 0 0 0 0.5212177155972926 Q12102 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.0 0.0 0.0 0.0 38.98931641204871 25.0 1.0 no 8555 chrXII_379675 23895 essential YLR115W 1690 + ACAATGTTAATCAAAATAGC D|564|E silent|GAC>GAT|D|564 CFT2 Cleavage Factor Two 859.0 0 0 0 0 -0.4744337141335144 Q12102 0.9532920122146606 1.0 32.06464411659965 25.0 1.0 no 8556 chrXII_379811 23897 essential YLR115W 1826 + ACACCGTGCTTCTCGTTACT H|610|Q silent|CAC>CAT|H|610 H|610|D H|610|Y CFT2 Cleavage Factor Two 859.0 0 0 0 0 0.2643694187600967 Q12102 0.9588389992713928 0.9473130106925964 0.9489949941635132 0.32072660326957697 0.2301987409591675 0.0719943642616272 54.19778081384777 50.0 1.0 no 8557 chrXII_379846r 23899 essential YLR115W 1864 - ATCAAAATTTTCTGCTTCTC D|628|H D|628|N CFT2 Cleavage Factor Two 859.0 0 0 0 0 0.8738720929356523 Q12102 0.9486550092697144 0.956179976463318 0.0 0.0 2.9475998878479004 1.4767999649047852 39.9824273082221 30.0 1.0 no 8558 chrXII_378545 23903 essential YLR115W 560 + ACTAAATGCTGCTTCTATAT L|188|V silent|CTA>TTA|L|188 CFT2 Cleavage Factor Two 859.0 0 0 0 0 0.5345479980822185 Q12102 0.9512209892272948 0.0 1.3384000062942505 40.79836092295562 30.0 1.0 no 8559 chrXII_380967 23905 essential YLR116W 145 + CTCTTCCATCAAAAATTAGT L|50|V L|50|F P|51|A P|51|S MSL5 Mud Synthetic-Lethal 476.0 0 0 0 0 0.560886288283166 Q12186 0.9512209892272948 0.9587849974632264 0.9562489986419678 0.9498909711837769 0.01712035946547985 0.05235796794295311 0.0379791259765625 0.03767352551221848 38.969606319528225 30.0 1.0 no 8560 chrXII_381012 23906 essential YLR116W 190 + ACTCCTATCAAGTCATGTTT S|65|C S|65|F Y|64|* silent|TAC>TAT|Y|64 MSL5 Mud Synthetic-Lethal 476.0 0 0 0 0 0.2396566289452149 Q12186 0.945252001285553 0.9294660091400146 0.02082300372421741 0.012919357977807522 46.372291762069146 35.0 1.0 no 8561 chrXII_381066 23908 essential YLR116W 244 + ACGATTTTGTGCCCCCCTCC N|82|K silent|AAC>AAT|N|82 MSL5 Mud Synthetic-Lethal 476.0 0 0 0 0 -0.273416813427421 Q12186 0.9439849853515624 0.3382944762706757 63.31944925623248 60.0 1.0 no 8562 chrXII_381015r 23909 essential YLR116W 196 - AATCCTAAACATGACTTGAT R|71|S silent|AGG>AGA|R|71 R|71|T R|71|K MSL5 Mud Synthetic-Lethal 476.0 0 0 0 0 0.08387628849306022 Q12186 0.9087679982185364 0.932735025882721 0.955805003643036 0.0 0.0 0.0 37.95846671268322 30.0 1.0 no 8563 chrXII_381078r 23910 essential YLR116W 259 - TGACCTATTTTTCCTGGAGG R|92|S silent|AGG>AGA|R|92 R|92|T R|92|K MSL5 Mud Synthetic-Lethal 476.0 0 1 0 0 0.09300046030118712 Q12186 0.9087679982185364 0.932735025882721 0.955805003643036 0.0 0.0 0.0 49.76574674131154 45.0 1.0 no 8564 chrXII_381110 23911 essential YLR116W 288 + CCACCAGTTTATGATGCCCA P|98|A P|98|S P|97|R P|97|L MSL5 Mud Synthetic-Lethal 476.0 0 1 0 0 0.016355122792091253 Q12186 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.0 0.0 0.01969154179096222 0.030753793194890026 55.81419330512091 50.0 1.0 no 8565 chrXII_381113r 23912 essential YLR116W 294 - TTACCTTGGGCATCATAAAC G|104|A G|104|D G|104|R G|104|S MSL5 Mud Synthetic-Lethal 476.0 0 1 0 0 0.28429210541567684 Q12186 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.0 0.0 0.0 0.0 44.214735113419806 40.0 1.0 no 8566 chrXII_381217 23914 essential YLR116W 395 + CATCCCTTACTTCGTTCCTC I|133|M silent|ATC>ATT|I|133 P|134|A P|134|S MSL5 Mud Synthetic-Lethal 476.0 0 0 0 0 0.7352578031425995 Q12186 0.9598389863967896 0.9562489986419678 0.9498909711837769 0.11919938027858736 0.0 0.0 56.00864917528094 50.0 1.0 no 8567 chrXII_381254r 23917 essential YLR116W 435 - TACTTGTCCTGAAATTTGGT K|151|N silent|AAG>AAA|K|151 MSL5 Mud Synthetic-Lethal 476.0 0 0 0 0 0.18083003550710414 Q12186 0.9355990290641784 0.0 2.262160062789917 43.95855617365561 35.0 1.0 no 8568 chrXII_381268 23919 essential YLR116W 446 + GGACAAGTATTATATCCCGG D|150|E silent|GAC>GAT|D|150 MSL5 Mud Synthetic-Lethal 476.0 0 0 0 0 -0.8748725747522604 Q12186 0.9532920122146606 1.0 -0.9381999969482422 46.44445949231829 45.0 1.0 no 8569 chrXII_381284r 23921 essential YLR116W 465 - ACATCAGGATACTGATCCAC V|162|L V|162|I D|161|H D|161|N MSL5 Mud Synthetic-Lethal 476.0 0 0 0 0 -0.22584143980007865 Q12186 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 0.14677052199840546 1.0 0.02703406848013401 0.08200045675039291 -1.3933000564575195 -1.0742000341415403 0.0955199971795082 0.07054000347852707 46.465401566298844 45.0 1.0 no 8570 chrXII_381332r 23923 essential YLR116W 513 - TTTCTTAACGTACGTCCACG R|177|T R|177|K MSL5 Mud Synthetic-Lethal 476.0 0 0 0 0 0.22464212704285494 Q12186 0.932735025882721 0.955805003643036 0.016052678227424618 1.0 1.250640034675598 -0.3687399923801422 46.266532588055895 45.0 1.0 no 8571 chrXII_381554r 23930 essential YLR116W 735 - TTCAAGTCATTCTGGCCTTC L|251|F silent|TTG>TTA|L|251 MSL5 Mud Synthetic-Lethal 476.0 0 0 0 0 0.9037974751057398 Q12186 0.9587849974632264 0.015219209715723991 0.8342199921607971 51.62054193171235 45.0 1.0 no 8572 chrXII_381629 23932 essential YLR116W 807 + AACAGGCCCTGTCCAATCTG N|270|K silent|AAC>AAT|N|270 P|272|A P|272|S MSL5 Mud Synthetic-Lethal 476.0 0 0 0 0 -0.08856660990588182 Q12186 0.9439849853515624 0.9562489986419678 0.9498909711837769 0.02431951835751533 0.699757993221283 0.096673883497715 54.58613168575363 55.00000000000001 1.0 no 8573 chrXII_381694r 23933 essential YLR116W 875 - AAACAATGCCCTGTATATTT V|298|L V|298|I MSL5 Mud Synthetic-Lethal 476.0 0 0 0 0 0.13423971945840596 Q12186 0.9539830088615416 0.9574310183525084 0.04371047392487526 1.0 41.729365931975735 30.0 1.0 no 8574 chrXII_381860r 23936 essential YLR116W 1041 - GATCTTTTTGGTGCTTGAAT R|353|T R|353|K MSL5 Mud Synthetic-Lethal 476.0 0 0 0 0 0.08344051703815825 Q12186 0.932735025882721 0.955805003643036 0.6148356795310974 1.0 44.59449534155544 35.0 1.0 no 8575 chrXII_381716 23937 essential YLR116W 894 + TGCAAAATATGTGGACAAAC C|299|W silent|TGC>TGT|C|299 MSL5 Mud Synthetic-Lethal 476.0 0 0 0 0 0.6315293555771226 Q12186 0.9286419749259948 0.0 35.406816013446814 35.0 1.0 no 8576 chrXII_383210 23941 essential YLR117C 1305 - CCTTTGAAAGTTTTAGCCTT G|442|R G|442|R CLF1 Crooked neck-Like Factor 687.0 0 0 0 0 -0.15465616480489375 Q12309 0.941340982913971 0.941340982913971 0.3607392609119415 0.3607392609119415 45.99605554775377 35.0 0.0 no 8577 chrXII_383226r 23942 essential YLR117C 1286 + AGCAATCGGTTTATGTCCTA A|430|G A|430|V I|431|M silent|ATC>ATT|I|431 CLF1 Crooked neck-Like Factor 687.0 0 0 0 0 0.05188030445074037 Q12309 0.9484469890594482 0.9504740238189696 0.9598389863967896 0.12856735289096832 0.04332045093178749 0.05167121440172195 48.47400625979082 40.0 0.0 no 8578 chrXII_383268r 23945 essential YLR117C 1244 + ACGACATGATGATGTACCGA R|416|G R|416|* H|417|D H|417|Y CLF1 Crooked neck-Like Factor 687.0 0 0 0 0 -1.4896535075072035 Q12309 0.8994590044021606 0.9473130106925964 0.9489949941635132 0.010667781345546246 0.2184983342885971 0.036916721612215035 44.9312983258593 45.0 0.0 no 8579 chrXII_383400r 23946 essential YLR117C 1112 + ATGCTATGTTGAGTTAGAAT C|372|W silent|TGC>TGT|C|372 CLF1 Crooked neck-Like Factor 687.0 0 0 0 0 -0.2000137060539325 Q12309 0.9286419749259948 0.051962368190288544 39.96175999380785 30.0 0.0 no 8580 chrXII_383553r 23947 essential YLR117C 959 + TGACACCTGGTGGCTGTACT D|321|E silent|GAC>GAT|D|321 T|322|S T|322|I CLF1 Crooked neck-Like Factor 687.0 0 0 0 0 -0.10115576511213403 Q12309 0.9532920122146606 0.9491789937019348 0.9472420215606691 0.08348695933818817 0.19403403997421265 0.009803345426917076 55.60296019379473 55.00000000000001 0.0 no 8581 chrXII_383713r 23950 essential YLR117C 799 + ATCAAATTGCTATAGAAAAA Q|268|E Q|268|* CLF1 Crooked neck-Like Factor 687.0 0 0 0 0 -0.35912389556261937 Q12309 0.9590039849281312 0.9907529950141908 30.03714544300692 20.0 0.0 no 8582 chrXII_384031 23954 essential YLR117C 484 - TGCATTAACCCCTGGCTCCA A|168|P A|168|T CLF1 Crooked neck-Like Factor 687.0 0 0 0 0 -0.8197008687061094 Q12309 0.9573720097541808 0.9523990154266356 0.023411158472299576 0.04024909064173698 59.197371640175895 55.00000000000001 0.0 no 8583 chrXII_384043 23955 essential YLR117C 472 - TGGCTCCAAGGAGCACCATT E|163|D silent|GAG>GAA|E|163 E|163|Q E|163|K CLF1 Crooked neck-Like Factor 687.0 0 0 0 0 -0.5638164365283121 Q12309 0.94931298494339 0.956179976463318 0.9475290179252625 0.12507903575897214 0.23190894722938535 0.3789350986480713 56.01210846228128 55.00000000000001 0.0 no 8584 chrXII_384058r 23957 essential YLR117C 454 + TACGATCACTGTACACCAAA R|153|G R|153|* S|154|* S|154|L CLF1 Crooked neck-Like Factor 687.0 0 0 0 0 -1.1182384684705802 Q12309 0.8994590044021606 0.9298099875450134 0.0 0.28389596939086914 42.579704630105475 40.0 0.0 no 8585 chrXII_384124 23958 essential YLR117C 391 - GTACCATAACTTGTCTACTC W|136|C W|136|* W|136|S W|136|* CLF1 Crooked neck-Like Factor 687.0 0 0 0 0 0.01932933210782229 Q12309 0.8858469724655151 0.8858469724655151 0.0 0.0 45.29993615840533 40.0 0.0 no 8586 chrXII_384213 23960 essential YLR117C 302 - CATCAATGTATCGTATCCAA D|107|H D|107|N CLF1 Crooked neck-Like Factor 687.0 0 0 0 0 0.7423572908486734 Q12309 0.9486550092697144 0.956179976463318 0.019270887598395348 0.04940937831997872 42.17102516478553 35.0 0.0 no 8587 chrXII_384388r 23964 essential YLR117C 124 + AACTTCGAGAGTATCAACGA L|43|V L|43|F R|44|G R|44|* CLF1 Crooked neck-Like Factor 687.0 0 0 0 0 0.7222200615486615 Q12309 0.9512209892272948 0.9587849974632264 0.8994590044021606 0.0 0.0 0.05916838347911835 40.84172339326335 40.0 0.0 no 8588 chrXII_384490 23967 essential YLR117C 25 - CGCAGAAACATGCGTATCAA A|15|P A|15|T CLF1 Crooked neck-Like Factor 687.0 0 0 0 0 1.1749726720681752 Q12309 0.9573720097541808 0.9523990154266356 0.057495031505823135 0.07599230855703354 43.190031200533895 45.0 0.0 no 8589 chrXII_384497 23968 essential YLR117C 18 - ACATGCGTATCAACGGCTGT V|13|L V|13|I silent|ACG>ACC|T|11 silent|ACG>ACA|T|11 CLF1 Crooked neck-Like Factor 687.0 0 0 0 0 0.5900088852270444 Q12309 0.9539830088615416 0.9574310183525084 0.04285222291946411 1.0 50.37658350812456 50.0 0.0 no 8590 chrXII_384936r 23970 no_effect YLR118C 450 + ATTCTGAAACAACATAAGAA L|152|V silent|CTG>TTG|L|152 TML25 acyl-protein Thioesterase with Multiple Localizations, protein of 25 kDa 227.0 0 0 0 0 -0.14670652328936895 Q12354 1.0 1.7070399522781372 31.54190109459711 25.0 0.0 no 8591 chrXII_385007r 23974 no_effect YLR118C 379 + CAACATCAGTTACTTTACCA T|128|R T|128|I S|129|* S|129|L TML25 acyl-protein Thioesterase with Multiple Localizations, protein of 25 kDa 227.0 0 0 0 0 0.5921821466774032 Q12354 0.030273212119936943 0.03036463260650635 0.44215354323387146 43.21146618365378 35.0 0.0 no 8592 chrXII_384990 23975 no_effect YLR118C 399 - ACTATACCACCGATTTTCCA V|140|L V|140|I G|138|A G|138|D TML25 acyl-protein Thioesterase with Multiple Localizations, protein of 25 kDa 227.0 0 0 0 0 0.27577489147364953 Q12354 0.35365989804267883 0.8603239059448242 0.6189337968826294 0.015391523018479347 49.2977170049939 40.0 0.0 no 8593 chrXII_385059 23976 no_effect YLR118C 330 - CCTCCGATAATAATCTGCTC G|116|A G|116|E G|117|R G|117|S TML25 acyl-protein Thioesterase with Multiple Localizations, protein of 25 kDa 227.0 0 1 0 0 0.2632909596452027 Q12354 0.0 0.0 0.0 0.0 47.09172181016397 45.0 0.0 no 8594 chrXII_385103 23978 no_effect YLR118C 286 - TTGCTTAACCGTCTTTTCTA K|101|N silent|AAG>AAA|K|101 TML25 acyl-protein Thioesterase with Multiple Localizations, protein of 25 kDa 227.0 0 0 0 0 0.39321580845416987 Q12354 0.1697975993156433 47.02854784002022 35.0 0.0 no 8595 chrXII_385196r 23980 no_effect YLR118C 190 + GCGGTGCATTGATGCCTGCT silent|GGC>GGG|G|64 silent|GGC>GGT|G|64 A|66|G A|66|V TML25 acyl-protein Thioesterase with Multiple Localizations, protein of 25 kDa 227.0 0 0 0 0 -1.4795070669546933 Q12354 0.3181474506855011 0.508827805519104 0.8662999868392944 0.6449599862098694 59.98663651311961 60.0 0.0 no 8596 chrXII_396407 23984 essential YLR127C 1893 - AGCTCCCTTTCTAAATCTAT E|637|D silent|GAG>GAA|E|637 E|637|Q E|637|K 0 0 0 0 0.4381961857137448 Q12440 0.94931298494339 0.956179976463318 0.9475290179252625 0.5846185088157654 0.4426625072956085 0.5277950763702393 47.22582359346457 35.0 0.0 no 8597 chrXII_396525 23985 essential YLR127C 1775 - CGGCTACTTCATGCATTTTA A|598|P A|598|T V|597|L V|597|I 0 0 0 0 -1.0332463018171545 Q12440 0.9573720097541808 0.9523990154266356 0.9539830088615416 0.9574310183525084 0.30063456296920776 0.6221345067024231 0.7505563497543335 0.7486647367477417 47.752796253037616 40.0 0.0 no 8598 chrXII_396757 23989 essential YLR127C 1543 - TTTCAAAGTGAATAATCTGT L|520|F silent|TTG>TTA|L|520 0 0 0 0 -0.5707653842137165 Q12440 0.9587849974632264 0.05984712764620781 34.71716057472298 25.0 0.0 no 8599 chrXII_396863 23990 essential YLR127C 1437 - TAACTTGATTTGATGTTACC S|485|T S|485|N 0 0 0 0 0.4936304501306237 Q12440 0.9512869715690612 0.9536849856376648 0.5885450839996338 0.5026881694793701 39.176998325624204 30.0 0.0 no 8600 chrXII_396878 23991 essential YLR127C 1422 - TTACCGGGAATCATGTCATT G|480|A G|480|D G|480|R G|480|S 0 0 0 0 -0.351905418394414 Q12440 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.7574446797370911 0.6287612915039062 0.6029363870620728 0.7282008528709412 46.23377434472508 40.0 0.0 no 8601 chrXII_396909r 23993 essential YLR127C 1388 + ACTCAATTATTATATAGCTT silent|CTC>CTG|L|464 silent|CTC>CTT|L|464 L|464|V L|464|F 0 0 0 0 0.004642905723966528 Q12440 0.9512209892272948 0.9587849974632264 0.536300539970398 0.2612966001033783 36.189527826669796 20.0 0.0 no 8602 chrXII_396910r 23994 essential YLR127C 1387 + TACTCAATTATTATATAGCT L|464|V L|464|F silent|CTC>CTG|L|464 silent|CTC>CTT|L|464 0 0 0 0 0.3077265869367893 Q12440 0.9512209892272948 0.9587849974632264 0.536300539970398 0.2612966001033783 35.385413381942726 20.0 0.0 no 8603 chrXII_396981 23996 essential YLR127C 1319 - CCCTCTTTCCTTTCACCTTG R|446|T R|446|K R|446|S silent|AGG>AGA|R|446 0 0 0 0 0.3612977435374176 Q12440 0.932735025882721 0.955805003643036 0.9087679982185364 57.886868940833274 50.0 0.0 no 8604 chrXII_397190 23998 essential YLR127C 1110 - TGCTTCCGCTCCTGAAAGTA K|376|N silent|AAG>AAA|K|376 silent|CGG>CGC|R|375 silent|CGG>CGA|R|375 0 0 0 0 -0.385678019451474 Q12440 0.9355990290641784 0.19384203851222992 52.991653563225725 50.0 0.0 no 8605 chrXII_397302 24003 essential YLR127C 998 - CGTCCACCGTAGTTACGCTG D|339|H D|339|N silent|GTG>GTC|V|338 silent|GTG>GTA|V|338 0 0 0 0 -0.3138839530842336 Q12440 0.9486550092697144 0.956179976463318 0.02863538265228272 0.08592905104160309 55.3291215287839 60.0 0.0 no 8606 chrXII_397305r 24004 essential YLR127C 992 + AAACCCCAGCGTAACTACGG N|332|K silent|AAC>AAT|N|332 P|333|A P|333|S 0 0 0 0 0.14661774920715226 Q12440 0.9439849853515624 0.9562489986419678 0.9498909711837769 0.3220805823802948 0.4354967772960663 0.2240542769432068 49.769383896068284 55.00000000000001 0.0 no 8607 chrXII_397440r 24006 essential YLR127C 857 + AATCTTTGATATATGCGTTT I|287|M silent|ATC>ATT|I|287 0 0 0 0 0.1862654957409132 Q12440 0.9598389863967896 0.018174298107624054 39.10473792908465 25.0 0.0 no 8608 chrXII_397517 24007 essential YLR127C 783 - GTCAGTTCGTGATCATCCTC silent|CTG>CTC|L|267 silent|CTG>CTA|L|267 0 0 0 0 -0.032541323205720764 Q12440 53.55800136187133 50.0 0.0 no 8609 chrXII_397544r 24008 essential YLR127C 753 + TCTCAGTTCTCTAAATTAGT Q|253|E Q|253|* S|252|C S|252|F 0 0 0 0 0.7249080895436394 Q12440 0.9590039849281312 0.945252001285553 0.9294660091400146 1.0 0.08764920383691788 0.12437327951192854 41.17558780701626 30.0 0.0 no 8610 chrXII_397567r 24009 essential YLR127C 730 + ACAAATTTATTAATCAATAT N|244|K silent|AAC>AAT|N|244 0 0 0 0 -0.05985098008195716 Q12440 0.9439849853515624 0.0 27.769204361165123 10.0 0.0 no 8611 chrXII_397723r 24011 essential YLR127C 574 + TGGCAGACAATTTAATCCAA A|193|G A|193|V 0 0 0 0 0.19353471026216773 Q12440 0.9484469890594482 0.9504740238189696 0.0867328867316246 0.2349055558443069 41.384112485590265 35.0 0.0 no 8612 chrXII_397917r 24013 essential YLR127C 380 + TCTAAAAGATATCCAACGAT L|128|V silent|CTA>TTA|L|128 0 0 0 0 0.5311547229389109 Q12440 0.9512209892272948 0.06144861876964569 36.133055544090844 30.0 0.0 no 8613 chrXII_398070r 24015 essential YLR127C 227 + TAGCATGATAAACACTAGTC S|77|R silent|AGC>AGT|S|77 0 1 0 0 0.04055376999812345 Q12440 0.9417110085487366 38.30957823481378 35.0 0.0 no 8614 chrXII_398127r 24020 essential YLR127C 170 + TCGTATTAAGAATATCATTA R|58|G R|58|C 0 0 0 0 0.4082112731567617 Q12440 0.8994590044021606 0.8926740288734436 0.0766259953379631 0.014107947237789631 33.113987068830966 20.0 0.0 no 8615 chrXII_398281 24024 essential YLR127C 19 - AACTTTCAAATCTCGAGTTG V|13|L V|13|I L|11|F silent|TTG>TTA|L|11 0 0 0 0 -0.8378779207293447 Q12440 0.9539830088615416 0.9574310183525084 0.9587849974632264 38.99035669964086 35.0 0.0 no 8616 chrXII_399709 24025 essential YLR129W 52 + CCTCCAATGCCAATTGTGTT S|19|C S|19|F silent|GCC>GCG|A|18 silent|GCC>GCT|A|18 DIP2 DOM34 Interacting Protein 943.0 0 0 0 0 -1.6967029709252062 Q12220 0.945252001285553 0.9294660091400146 0.0029915114864706997 0.0014127269387245178 51.95466052085635 45.0 1.0 no 8617 chrXII_399709r 24026 essential YLR129W 55 - CCAAACACAATTGGCATTGG W|25|S W|25|* V|24|L V|24|I DIP2 DOM34 Interacting Protein 943.0 0 0 0 0 -1.1060284165489291 Q12220 0.8858469724655151 0.9539830088615416 0.9574310183525084 0.05295206978917122 0.1538768857717514 0.7834763526916504 43.696558545913035 45.0 1.0 no 8618 chrXII_399712r 24027 essential YLR129W 58 - TATCCAAACACAATTGGCAT W|25|C W|25|* W|25|S W|25|* DIP2 DOM34 Interacting Protein 943.0 0 0 0 0 -0.41706731865790736 Q12220 0.8858469724655151 0.8858469724655151 0.023403165861964226 0.05295206978917122 41.64217248992645 35.0 1.0 no 8619 chrXII_399735r 24030 essential YLR129W 81 - TTACTATTTCCGGATGACGC S|33|T S|33|N DIP2 DOM34 Interacting Protein 943.0 0 0 0 0 -0.7791670488441337 Q12220 0.9512869715690612 0.9536849856376648 0.5770552158355713 0.4695545434951782 47.20317961660044 45.0 1.0 no 8620 chrXII_399791 24034 essential YLR129W 134 + TCTCGAGGACGTTAATATAT silent|CTC>CTG|L|46 silent|CTC>CTT|L|46 L|46|V L|46|F DIP2 DOM34 Interacting Protein 943.0 0 0 0 0 1.7155813253232317 Q12220 0.9512209892272948 0.9587849974632264 0.13647469878196716 0.0890359953045845 40.54300277445157 35.0 1.0 no 8621 chrXII_399891r 24037 essential YLR129W 237 - TCCAAATATGTACACTCGGC L|85|F silent|TTG>TTA|L|85 E|86|Q E|86|K DIP2 DOM34 Interacting Protein 943.0 0 0 0 0 0.1363006981751214 Q12220 0.9587849974632264 0.956179976463318 0.9475290179252625 0.01505136862397194 0.5227991938591003 0.86519855260849 45.94457470798557 45.0 1.0 no 8622 chrXII_398280 24038 essential YLR127C 20 - TAACTTTCAAATCTCGAGTT V|13|L V|13|I 0 0 0 0 0.6323610211262155 Q12440 0.9539830088615416 0.9574310183525084 38.42616467515779 30.0 0.0 no 8623 chrXII_400027 24039 essential YLR129W 370 + TAACATTATTACAATTTGAT T|125|R T|125|I DIP2 DOM34 Interacting Protein 943.0 0 0 0 0 -1.094345106064802 Q12220 0.9476869702339172 0.9472420215606691 0.002896151738241315 0.0032945007551461463 30.992234378074894 15.0 1.0 no 8624 chrXII_400137 24042 essential YLR129W 480 + TCACACAAGGATTCCATTAC H|162|D H|162|Y S|161|* S|161|L DIP2 DOM34 Interacting Protein 943.0 0 0 0 0 0.3762097408120975 Q12220 0.9473130106925964 0.9489949941635132 0.9298099875450134 0.0 0.0 0.0042024548165500155 43.74990529741036 40.0 1.0 no 8625 chrXII_400198r 24043 essential YLR129W 544 - TAGCTTGATCATTCCATCTT K|187|N silent|AAG>AAA|K|187 DIP2 DOM34 Interacting Protein 943.0 0 0 0 0 0.5428840811156982 Q12220 0.9355990290641784 0.0 47.56650825007522 35.0 1.0 no 8626 chrXII_400495r 24046 essential YLR129W 841 - TCTAATTCTGAAAGTCTCGA R|287|T R|287|K DIP2 DOM34 Interacting Protein 943.0 0 0 0 0 0.11100361049266838 Q12220 0.932735025882721 0.955805003643036 0.009142882190644741 0.12679161131381989 40.0393112785863 35.0 1.0 no 8627 chrXII_400791r 24048 essential YLR129W 1137 - TCAATAGTATGTGTCTTGAG E|386|Q E|386|K DIP2 DOM34 Interacting Protein 943.0 0 0 0 0 -0.5411575880493331 Q12220 0.956179976463318 0.9475290179252625 0.16027785837650302 0.027149148285388947 40.530647419214006 35.0 1.0 no 8628 chrXII_400869 24049 essential YLR129W 1212 + TTACTTGCCACAGCATCCAA L|406|V L|406|F DIP2 DOM34 Interacting Protein 943.0 0 0 0 0 -0.18335301561274944 Q12220 0.9512209892272948 0.9587849974632264 0.2977511286735535 0.017295343801379204 51.43354315341071 45.0 1.0 no 8629 chrXII_401056r 24050 essential YLR129W 1402 - CGCATCATGTGCATCTTCAA A|474|P A|474|T D|473|H D|473|N DIP2 DOM34 Interacting Protein 943.0 0 0 0 0 0.04205165339395178 Q12220 0.9573720097541808 0.9523990154266356 0.9486550092697144 0.956179976463318 0.026415031403303143 0.05129315331578255 0.016517698764801025 0.0704658105969429 48.969939425900286 45.0 1.0 no 8630 chrXII_401101r 24053 essential YLR129W 1447 - CACTAATCGTTTACCATCTG V|489|L V|489|M DIP2 DOM34 Interacting Protein 943.0 0 0 0 0 -0.3230453428076449 Q12220 0.9539830088615416 0.9587630033493042 0.12089376896619795 0.0057184044271707535 43.855544242209085 40.0 1.0 no 8631 chrXII_401088 24054 essential YLR129W 1431 + TCGCTAGATCTGACCTCAGA L|479|V silent|CTA>TTA|L|479 S|478|W S|478|L DIP2 DOM34 Interacting Protein 943.0 0 0 0 0 -0.1810418512447577 Q12220 0.9512209892272948 0.9288619756698608 0.9298099875450134 0.020456895232200626 0.0020628042984753847 0.010477936826646328 51.43647443071677 50.0 1.0 no 8632 chrXII_401134 24055 essential YLR129W 1477 + CCGATAAAACTGTCAAGTTT silent|GCC>GCG|A|493 silent|GCC>GCT|A|493 DIP2 DOM34 Interacting Protein 943.0 0 0 0 0 0.3171158904413444 Q12220 39.526977201641614 35.0 1.0 no 8633 chrXII_401208r 24057 essential YLR129W 1554 - TCATGGTGCAGTTTTAAAAC D|525|H D|525|N DIP2 DOM34 Interacting Protein 943.0 0 0 0 0 0.11933947974816896 Q12220 0.9486550092697144 0.956179976463318 0.023157402873039246 0.10586293786764144 40.11663700264046 35.0 1.0 no 8634 chrXII_401219 24058 essential YLR129W 1562 + ACTGCACCATGATACAACTT L|522|V silent|CTG>TTG|L|522 H|523|D H|523|Y DIP2 DOM34 Interacting Protein 943.0 0 0 0 0 -0.2538522632619095 Q12220 0.9512209892272948 0.9473130106925964 0.9489949941635132 0.01941046491265297 0.31334125995635986 0.2580969631671905 45.421319700130645 40.0 1.0 no 8635 chrXII_401435 24060 essential YLR129W 1778 + AGACAAAAATATCAAGATTT D|594|E silent|GAC>GAT|D|594 DIP2 DOM34 Interacting Protein 943.0 0 0 0 0 0.22768366290124625 Q12220 0.9532920122146606 0.0 29.639167943674522 20.0 1.0 no 8636 chrXII_401494r 24061 essential YLR129W 1840 - GTTCATAATCGAATCCTGAT M|619|I M|619|I DIP2 DOM34 Interacting Protein 943.0 0 0 0 0 -0.0713500870407867 Q12220 0.9553959965705872 0.9553959965705872 0.030068308115005493 0.030068308115005493 42.07076784640759 35.0 1.0 no 8637 chrXII_401624 24065 essential YLR129W 1967 + TCAGAGCGAAGTTTGGGCTT Q|657|E Q|657|* S|658|R silent|AGC>AGT|S|658 DIP2 DOM34 Interacting Protein 943.0 0 0 0 0 -2.3750199342047567 Q12220 0.9590039849281312 0.9417110085487366 0.1342645138502121 0.00552879273891449 51.1712944307335 50.0 1.0 yes 8638 chrXII_401723r 24070 essential YLR129W 2069 - TTTCCTCTTCTAAAAATACC E|696|Q E|696|K E|695|D silent|GAG>GAA|E|695 DIP2 DOM34 Interacting Protein 943.0 0 0 0 0 -0.07802250097254304 Q12220 0.956179976463318 0.9475290179252625 0.94931298494339 0.10195478796958923 0.009405339136719705 0.0 39.64877613637185 30.0 1.0 no 8639 chrXII_407525r 24071 essential YLR132C 608 + TTTCAAAACGATAATAGCTG F|204|L silent|TTC>TTT|F|204 0 0 0 0 -0.2322764982107266 Q12208 0.9387490153312684 1.0 34.37624436059326 30.0 0.0 no 8640 chrXII_407527 24072 essential YLR132C 609 - TCAGCTATTATCGTTTTGAA E|210|Q E|210|K A|209|P A|209|T 0 0 0 0 0.6001106472828408 Q12208 0.956179976463318 0.9475290179252625 0.9573720097541808 0.9523990154266356 0.5558797717094421 0.6066961288452148 0.2450332045555115 0.5045246481895447 41.3712245177241 30.0 0.0 no 8641 chrXII_407561r 24073 essential YLR132C 572 + TGTCTCAGAATGTCCCAATA silent|GTC>GTG|V|192 silent|GTC>GTT|V|192 S|193|* S|193|L 0 0 0 0 0.6513190857604156 Q12208 0.9298099875450134 0.11114624887704848 47.01215797285562 40.0 0.0 no 8642 chrXII_407730 24075 essential YLR132C 406 - AAACAACAACGATCGAGTTA L|141|F silent|TTG>TTA|L|141 L|140|F silent|TTG>TTA|L|140 0 0 0 0 1.3449554606013443 Q12208 0.9587849974632264 0.9587849974632264 0.698706865310669 0.042920898646116264 36.440793388403335 35.0 0.0 no 8643 chrXII_407683r 24076 essential YLR132C 450 + TTCATTCAAGAAATGCGTAA F|151|L silent|TTC>TTT|F|151 Q|153|E Q|153|* 0 0 0 0 -0.38748541793246144 Q12208 0.9387490153312684 0.9590039849281312 0.4113741815090179 1.0 36.98545197273978 30.0 0.0 no 8644 chrXII_407776r 24077 essential YLR132C 357 + CCGTTGTTCATCTCACACTT P|120|R P|120|L 0 0 0 0 0.2843922748672003 Q12208 0.9432820081710817 0.9430609941482544 0.0 0.0 51.71594926751754 45.0 0.0 no 8645 chrXII_407777r 24080 essential YLR132C 356 + CCCGTTGTTCATCTCACACT P|120|R P|120|L P|120|A P|120|S 0 0 0 0 0.563618422170079 Q12208 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 55.17569711926632 50.0 0.0 no 8646 chrXII_407800 24081 essential YLR132C 336 - TCAAAATCCACCAGTTGATA D|119|H D|119|N 0 0 0 0 0.06413689279041887 Q12208 0.9486550092697144 0.956179976463318 0.035377878695726395 0.09817834198474884 42.33555990352511 35.0 0.0 no 8647 chrXII_407807r 24082 essential YLR132C 326 + CACTAATCCGTATCAACTGG T|110|S T|110|I 0 0 0 0 1.54291876922405 Q12208 0.9491789937019348 0.9472420215606691 0.7514631152153015 0.10156950354576112 44.208125804438964 45.0 0.0 no 8648 chrXII_407810r 24083 essential YLR132C 323 + ATACACTAATCCGTATCAAC Y|109|* silent|TAC>TAT|Y|109 T|110|S T|110|I 0 0 0 0 -1.4210405651692206 Q12208 0.9491789937019348 0.9472420215606691 0.7514631152153015 0.10156950354576112 40.124908292764076 35.0 0.0 no 8649 chrXII_407907r 24085 essential YLR132C 226 + GTTCGTTCACATATTTTGAG S|77|W S|77|L 0 0 0 0 -3.394275978666012 Q12208 0.9288619756698608 0.9298099875450134 0.0027677207253873353 0.012956423684954643 42.46364088252608 35.0 0.0 yes 8650 chrXII_407962 24086 essential YLR132C 174 - TCGTACTTTTGTAAATTCGG E|65|Q E|65|K K|63|N silent|AAG>AAA|K|63 0 0 0 0 0.5208128976508891 Q12208 0.956179976463318 0.9475290179252625 0.9355990290641784 0.3679104745388031 0.5021603107452393 0.0 40.44002941371275 35.0 0.0 no 8651 chrXII_407992 24087 essential YLR132C 144 - TACTTCAATATAATTGAATC K|54|N silent|AAG>AAA|K|54 L|53|F silent|TTG>TTA|L|53 0 0 0 0 0.6796696218950371 Q12208 0.9355990290641784 0.9587849974632264 0.0 0.16257359087467196 30.80040973716405 20.0 0.0 no 8652 chrXII_408011r 24088 essential YLR132C 122 + CACTGATTTACCTGCAATAC T|42|S T|42|I 1 Series([], Name: modification, dtype: object) 0 0 0 -0.3774788825788181 Q12208 0.9491789937019348 0.9472420215606691 0.8671059012413025 0.307808130979538 43.453905663748344 40.0 0.0 no 8653 chrXII_423691r 24092 essential YLR141W 11 - CGACGTACTTCCGCAATTGT V|10|L V|10|I 0 0 0 0 0.8886183496994325 Q02983 0.7057769894599915 0.4557045102119446 49.600524069340274 50.0 1.0 no 8654 chrXII_423782r 24096 essential YLR141W 102 - CTCTTTACATGTACTTTGGA K|40|N silent|AAG>AAA|K|40 0 0 0 0 -0.07623786325933847 Q02983 0.5056639313697815 43.89498149404949 35.0 1.0 no 8655 chrXII_423847 24099 essential YLR141W 164 + CTCTAGCGTTGGTGTAGACT S|56|C S|56|F S|57|R silent|AGC>AGT|S|57 0 0 0 0 -0.2771636016282521 Q02983 0.2005333751440048 0.7120718359947205 0.6545034050941467 51.94707187675351 50.0 1.0 no 8656 chrXII_423950r 24102 essential YLR141W 270 - ATCTCCATGGCGCTCTTCCG E|96|D silent|GAG>GAA|E|96 E|96|Q E|96|K 0 0 0 0 -1.223832748043958 Q02983 0.0 0.0 0.0 59.54557701372989 60.0 1.0 no 8657 chrXII_424131r 24117 essential YLR141W 451 - TCCTTCCTCATCGGCAACCT G|157|R G|157|R G|157|A G|157|E 0 0 0 0 -0.4271243743130115 Q02983 0.4162122011184693 0.4162122011184693 0.6677026748657227 1.0 58.668691575697316 55.00000000000001 1.0 no 8658 chrXII_424140r 24118 essential YLR141W 460 - CTCGCAGTGTCCTTCCTCAT E|160|Q E|160|K C|159|S C|159|Y 0 0 0 0 0.4920666988930841 Q02983 0.11956487596035005 0.1643114537000656 1.0 0.7494335174560547 59.83755627420447 55.00000000000001 1.0 no 8659 chrXII_424165r 24120 essential YLR141W 485 - TCCAGCTTTCATAATCGATA W|168|S W|168|* W|168|C W|168|* 0 0 0 0 -0.9127670873525232 Q02983 0.0 0.0 44.503272328834896 35.0 1.0 no 8660 chrXII_424377r 24138 essential YLR141W 697 - CGACTTGTGTCCTCGAGATT K|238|N silent|AAG>AAA|K|238 0 0 0 0 -0.15949014929351882 Q02983 0.4928034245967865 50.74156046060341 50.0 1.0 no 8661 chrXII_424390 24139 essential YLR141W 707 + ACACAAGTCGCTACCGACGG H|237|Q silent|CAC>CAT|H|237 H|237|D H|237|Y 0 0 0 0 -0.8107503245188601 Q02983 0.4227904081344605 0.9106875658035278 0.09729890525341034 50.98648529612712 60.0 1.0 no 8662 chrXII_432343r 24146 essential YLR145W 178 - TTCAACATCTTTAAGGCGTT E|66|Q E|66|K V|65|L V|65|I 0 0 0 0 -0.5347803400477598 Q12530 0.14552637934684753 0.13169775903224945 0.6276234984397888 0.3842834830284119 43.41060910036202 35.0 1.0 no 8663 chrXII_434286 24155 essential YLR147C 158 - CCATGTGTGTTACAGCCCCC M|59|I M|59|I SMD3 101.0 0 0 0 0 -1.1133915516761903 P43321 0.03951048105955124 0.03951048105955124 0.6402400135993958 0.6402400135993958 -0.2659600079059601 -0.2659600079059601 62.10377101789487 60.0 0.0 no 8664 chrXII_434372r 24157 essential YLR147C 69 + ACAACGGGAGCGACTTATCG T|24|R T|24|I T|25|R T|25|M SMD3 101.0 0 0 0 0 -1.5629087136534447 P43321 0.15703196823596954 0.05827227607369422 0.01292006392031908 0.0060240793973207465 0.12426000088453293 0.04278000071644783 -0.3740200102329254 -1.0122799873352049 47.18604721316285 55.00000000000001 0.0 no 8665 chrXII_434400r 24158 essential YLR147C 41 + ACAGGGACATATCGTTTCTC Q|15|E Q|15|* SMD3 101.0 0 0 0 0 -0.9314247203430028 P43321 1.0 47.412277979200155 45.0 0.0 no 8666 chrXII_434665 24159 high_effect YLR148W 24 + GTTCAGTTACAATTCCTCAC Q|10|E Q|10|* PEP3 carboxyPEPtidase Y-deficient 918.0 0 0 0 0 0.324983729775027 P27801 0.9590039849281312 0.3549123406410217 0.1471800059080124 46.60461127483006 40.0 1.0 no 8667 chrXII_434666 24160 high_effect YLR148W 25 + TTCAGTTACAATTCCTCACA Q|10|E Q|10|* PEP3 carboxyPEPtidase Y-deficient 918.0 0 0 0 0 -0.26683474562124776 P27801 0.9590039849281312 0.3549123406410217 0.1471800059080124 45.29516869842002 35.0 1.0 no 8668 chrXII_434693r 24161 high_effect YLR148W 55 - GACTTTCAAATGCGTAAGTT V|25|L V|25|I L|23|F silent|TTG>TTA|L|23 PEP3 carboxyPEPtidase Y-deficient 918.0 0 0 0 0 0.4701633008941656 P27801 0.9539830088615416 0.9574310183525084 0.9587849974632264 0.0 0.0 0.12528997659683228 1.062656044960022 -0.6054999828338623 4.695821762084961 40.78087214146996 35.0 1.0 no 8669 chrXII_434726 24162 high_effect YLR148W 85 + AACTTATAGTAACGACACAA L|30|V L|30|F PEP3 carboxyPEPtidase Y-deficient 918.0 0 0 0 0 -0.5889029779006155 P27801 0.9512209892272948 0.9587849974632264 0.12844859063625336 0.2594566643238068 3.1878480911254883 3.4744760990142822 35.34460657177135 30.0 1.0 no 8670 chrXII_434776r 24163 high_effect YLR148W 138 - TCAAAGTGATTGACGATGGC D|53|H D|53|N PEP3 carboxyPEPtidase Y-deficient 918.0 0 0 0 0 -0.6147201956815153 P27801 0.9486550092697144 0.956179976463318 0.1961248219013214 0.5275685787200928 0.10954000055789948 0.3993200063705444 42.745249133749034 45.0 1.0 no 8671 chrXII_434863 24165 high_effect YLR148W 222 + ATTCTTATTCGAACCAACTT L|76|V L|76|F PEP3 carboxyPEPtidase Y-deficient 918.0 0 0 0 0 0.5090438994293109 P27801 0.9512209892272948 0.9587849974632264 0.2786923348903656 0.35687878727912903 0.7254999876022339 1.0419199466705322 40.979531631022724 30.0 1.0 no 8672 chrXII_434876r 24166 high_effect YLR148W 238 - CAACATATACCGGCCAAAGT M|85|I M|85|I PEP3 carboxyPEPtidase Y-deficient 918.0 0 0 0 0 0.6860360606444666 P27801 0.9553959965705872 0.9553959965705872 0.022682134062051773 0.022682134062051773 1.3487399816513062 1.3487399816513062 45.771027375474546 45.0 1.0 no 8673 chrXII_434886r 24168 high_effect YLR148W 248 - CATCCTTTAGCAACATATAC D|89|H D|89|N K|88|N silent|AAG>AAA|K|88 PEP3 carboxyPEPtidase Y-deficient 918.0 0 0 0 0 0.8512536553565164 P27801 0.9486550092697144 0.956179976463318 0.9355990290641784 0.3186634182929993 0.6133353114128113 0.4748342633247376 -0.07631999999284744 -0.00028000000747852033 1.429900050163269 41.791018855628685 35.0 1.0 no 8674 chrXII_434967 24169 high_effect YLR148W 326 + CAACGAAACCACCTTTCTGA N|110|K silent|AAC>AAT|N|110 PEP3 carboxyPEPtidase Y-deficient 918.0 0 0 0 0 -0.048079820078485984 P27801 0.9439849853515624 0.16963215172290802 0.4367400109767914 45.037105187581176 45.0 1.0 no 8675 chrXII_434968 24170 high_effect YLR148W 327 + AACGAAACCACCTTTCTGAT N|110|K silent|AAC>AAT|N|110 PEP3 carboxyPEPtidase Y-deficient 918.0 0 0 0 0 -0.4931401870558822 P27801 0.9439849853515624 0.16963215172290802 0.4367400109767914 43.87388687534934 40.0 1.0 no 8676 chrXII_435187r 24173 high_effect YLR148W 549 - TCAAATTGCTCAGATTCATC E|190|Q E|190|K PEP3 carboxyPEPtidase Y-deficient 918.0 0 0 0 0 1.2634582089208086 P27801 0.956179976463318 0.9475290179252625 0.13250169157981873 0.02289764769375324 0.21007999777793884 0.2706199884414673 41.23033940780453 35.0 1.0 no 8677 chrXII_435275r 24175 high_effect YLR148W 637 - ATCACCAAAGACAATTCCAT D|219|H D|219|N G|218|A G|218|D PEP3 carboxyPEPtidase Y-deficient 918.0 0 0 0 0 0.779152576169966 P27801 0.9486550092697144 0.956179976463318 0.9499930143356324 0.9446240067481996 0.03848033770918846 0.4855294227600098 0.10952376574277878 0.08452801406383514 2.6847660541534424 0.3840399980545044 3.088979959487915 2.700655937194824 42.190304111136754 35.0 1.0 no 8678 chrXII_435414r 24178 high_effect YLR148W 776 - TCAAAACTATATCCTTGATG L|265|F silent|TTG>TTA|L|265 V|264|L V|264|I PEP3 carboxyPEPtidase Y-deficient 918.0 0 0 0 0 0.4596278090456217 P27801 0.9587849974632264 0.9539830088615416 0.9574310183525084 0.02963211014866829 0.4014784395694733 0.3869861364364624 4.955426216125488 1.207260012626648 -0.03539999946951866 36.71429052320696 30.0 1.0 no 8679 chrXII_435545r 24181 high_effect YLR148W 907 - TTTCTCATTACTATCAGTGT E|308|D silent|GAG>GAA|E|308 E|308|Q E|308|K PEP3 carboxyPEPtidase Y-deficient 918.0 0 0 0 0 0.32583772595244703 P27801 0.94931298494339 0.956179976463318 0.9475290179252625 0.11074737459421158 0.05006367713212967 0.04898875579237938 2.567078113555908 1.0054600238800049 1.489199995994568 43.557178694457896 30.0 1.0 no 8680 chrXII_435642 24182 high_effect YLR148W 1001 + TATCGAAAATGAGCCTAATT I|335|M silent|ATC>ATT|I|335 PEP3 carboxyPEPtidase Y-deficient 918.0 0 0 0 0 0.6062655177996784 P27801 0.9598389863967896 0.170841246843338 -0.5921400189399719 37.192292666869385 30.0 1.0 no 8681 chrXII_435697 24183 high_effect YLR148W 1056 + GACAAGGCCCTATCGTTGAA D|353|E silent|GAC>GAT|D|353 PEP3 carboxyPEPtidase Y-deficient 918.0 0 0 0 0 0.4983345797948626 P27801 0.9532920122146606 0.7244730591773987 50.02579723539446 50.0 1.0 no 8682 chrXII_435768r 24185 high_effect YLR148W 1130 - AATCTTTAGCAGTGTGGAAA D|383|H D|383|N PEP3 carboxyPEPtidase Y-deficient 918.0 0 0 0 0 0.19482294527311925 P27801 0.9486550092697144 0.956179976463318 0.11105480045080184 0.3460198640823364 41.13846290955314 35.0 1.0 no 8683 chrXII_435792 24186 high_effect YLR148W 1151 + TCATTCCGCGGCTCAAACTT H|385|D H|385|Y S|386|C S|386|F PEP3 carboxyPEPtidase Y-deficient 918.0 0 0 0 0 0.4829533140975102 P27801 0.9473130106925964 0.9489949941635132 0.945252001285553 0.9294660091400146 0.6301784515380859 0.2091927081346512 0.012569471262395382 0.01902002654969692 51.770101241321974 50.0 1.0 no 8684 chrXII_435923r 24190 high_effect YLR148W 1285 - GACGACTTGAGTTGATTTCC V|435|L V|435|I V|434|L V|434|I PEP3 carboxyPEPtidase Y-deficient 918.0 0 0 0 0 -0.5719351590502633 P27801 0.9539830088615416 0.9574310183525084 0.9539830088615416 0.9574310183525084 1.0 0.8459084033966064 0.26321086287498474 1.0 46.45297258325979 45.0 1.0 no 8685 chrXII_435922r 24191 high_effect YLR148W 1284 - ACGACTTGAGTTGATTTCCA V|435|L V|435|I V|434|L V|434|I PEP3 carboxyPEPtidase Y-deficient 918.0 0 0 0 0 0.09757418396685902 P27801 0.9539830088615416 0.9574310183525084 0.9539830088615416 0.9574310183525084 1.0 0.8459084033966064 0.26321086287498474 1.0 46.535201174050655 40.0 1.0 no 8686 chrXII_435935 24192 high_effect YLR148W 1294 + CTCAAGTCGTCTTGTCGAGT Q|433|E Q|433|* PEP3 carboxyPEPtidase Y-deficient 918.0 0 0 0 0 0.21369945604597887 P27801 0.9590039849281312 0.4528842866420746 51.09242858725401 50.0 1.0 no 8687 chrXII_436148r 24195 high_effect YLR148W 1510 - TTCGTTTTGCCGGTTTTGTT E|510|Q E|510|K PEP3 carboxyPEPtidase Y-deficient 918.0 0 0 0 0 -0.6942040758711356 P27801 0.956179976463318 0.9475290179252625 0.15179333090782166 0.15857696533203125 52.2626711704022 40.0 1.0 no 8688 chrXII_436056r 24196 high_effect YLR148W 1418 - TCGATTTCTCCTTGAGATTC silent|TCG>TCC|S|479 silent|TCG>TCA|S|479 PEP3 carboxyPEPtidase Y-deficient 918.0 0 0 0 0 1.0813313022880315 P27801 46.667697258098485 40.0 1.0 no 8689 chrXII_436284r 24197 high_effect YLR148W 1646 - TCAAAGAGTACTTATAGACT L|555|F silent|TTG>TTA|L|555 PEP3 carboxyPEPtidase Y-deficient 918.0 0 0 0 0 0.644198657494196 P27801 0.9587849974632264 0.05705146864056587 36.576288214928006 30.0 1.0 no 8690 chrXII_436308 24198 high_effect YLR148W 1667 + TCTCTTATTGAATTCACCAG silent|CTC>CTG|L|557 silent|CTC>CTT|L|557 L|557|V L|557|F PEP3 carboxyPEPtidase Y-deficient 918.0 0 0 0 0 -0.2265402770038215 P27801 0.9512209892272948 0.9587849974632264 0.0 0.0 42.668070811208956 35.0 1.0 no 8691 chrXII_436501r 24200 high_effect YLR148W 1863 - ACTATTGGATTACACATTTT V|628|L V|628|M PEP3 carboxyPEPtidase Y-deficient 918.0 0 0 0 0 1.3926613703589557 P27801 0.9539830088615416 0.9587630033493042 0.4041672050952912 0.1367446482181549 38.76647451023581 25.0 1.0 no 8692 chrXII_436558r 24201 high_effect YLR148W 1920 - TCTAGTATCATATCGTTTCT E|647|Q E|647|K PEP3 carboxyPEPtidase Y-deficient 918.0 0 0 0 0 0.3908288505181382 P27801 0.956179976463318 0.9475290179252625 0.051773611456155784 0.043649200350046165 43.18866742075119 30.0 1.0 no 8693 chrXII_436689 24203 high_effect YLR148W 2048 + AACACGTTTAAACTTATTCG T|684|R T|684|I R|685|G R|685|C PEP3 carboxyPEPtidase Y-deficient 918.0 0 0 0 0 0.722169558206308 P27801 0.9476869702339172 0.9472420215606691 0.8994590044021606 0.8926740288734436 0.02650121785700321 0.019610224291682243 0.22281932830810547 0.04256584867835045 35.983423232509715 30.0 1.0 no 8694 chrXII_446032r 24204 essential YLR153C 1521 + TATCCTGGTCACTATTTCAC P|509|A P|509|S P|509|R P|509|L ACS2 Acetyl CoA Synthetase 683.0 0 1 0 0 0.408521831835542 P52910 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.14666754007339478 0.07119125127792357 0.16406260430812836 0.02988823316991329 47.6802142898581 40.0 0.0 no 8695 chrXII_446047r 24206 essential YLR153C 1506 + ACTTACTTGAAACCTTATCC T|503|S T|503|I Y|504|* silent|TAC>TAT|Y|504 ACS2 Acetyl CoA Synthetase 683.0 0 1 0 0 -0.4671606542581977 P52910 0.9491789937019348 0.9472420215606691 0.08917506039142609 0.045751675963401794 42.616892146997145 35.0 0.0 no 8696 chrXII_446060 24207 essential YLR153C 1496 - TCAAGTAAGTATCCATGTAA L|505|F silent|TTG>TTA|L|505 ACS2 Acetyl CoA Synthetase 683.0 0 1 0 0 1.2136852833265386 P52910 0.9587849974632264 1.0 39.08757752880041 30.0 0.0 no 8697 chrXII_446072r 24211 essential YLR153C 1481 + GAACCACCACGACCGTTACA N|495|K silent|AAC>AAT|N|495 H|496|D H|496|Y ACS2 Acetyl CoA Synthetase 683.0 0 0 0 0 -0.05803749910809222 P52910 0.9439849853515624 0.9473130106925964 0.9489949941635132 0.08909117430448532 1.0 0.02339114248752594 51.50047975333529 55.00000000000001 0.0 no 8698 chrXII_446118r 24212 essential YLR153C 1435 + TCCTTGCCGTTAAATCACCA L|480|V L|480|F silent|GTC>GTG|V|479 silent|GTC>GTT|V|479 ACS2 Acetyl CoA Synthetase 683.0 0 0 0 0 -0.542493504028637 P52910 0.9512209892272948 0.9587849974632264 0.0 0.0 51.36256690629892 45.0 0.0 no 8699 chrXII_446161 24213 essential YLR153C 1395 - TCTAATTCCACACCTGTAAC E|472|Q E|472|K ACS2 Acetyl CoA Synthetase 683.0 0 0 0 0 -1.3589448298613611 P52910 0.956179976463318 0.9475290179252625 0.4655536413192749 0.691285252571106 45.09840570262384 40.0 0.0 no 8700 chrXII_446255r 24214 essential YLR153C 1298 + TTCTCATTTAATTGCTCCTT S|434|C S|434|F H|435|D H|435|Y ACS2 Acetyl CoA Synthetase 683.0 0 0 0 0 0.4805539368258834 P52910 0.945252001285553 0.9294660091400146 0.9473130106925964 0.9489949941635132 0.09656371176242827 0.00295277638360858 0.1993795186281204 0.9562098979949952 45.693444618826106 30.0 0.0 no 8701 chrXII_446348r 24217 essential YLR153C 1205 + ACCAATCTCTCCAGACTTAT P|403|R P|403|L P|403|A P|403|S ACS2 Acetyl CoA Synthetase 683.0 0 0 0 0 -0.7583551606336301 P52910 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 48.29672046923656 40.0 0.0 no 8702 chrXII_446384r 24218 essential YLR153C 1169 + CACTTCCTCATTACGTGTCT T|391|S T|391|I S|392|C S|392|F ACS2 Acetyl CoA Synthetase 683.0 0 1 0 0 0.1444598286311805 P52910 0.9491789937019348 0.9472420215606691 0.945252001285553 0.9294660091400146 0.2842417657375336 0.19617782533168796 0.004961723927408457 0.00460320757701993 51.45106630655192 45.0 0.0 no 8703 chrXII_446504 24219 essential YLR153C 1052 - TCCAATATCTACCATAATCT W|357|S W|357|* W|357|C W|357|* ACS2 Acetyl CoA Synthetase 683.0 0 0 0 0 -2.0913208499239517 P52910 0.8858469724655151 0.8858469724655151 0.04339128732681274 0.0215340256690979 41.95975894344457 30.0 0.0 yes 8704 chrXII_446515r 24221 essential YLR153C 1038 + ACTCCTGCCTACCCAGATTA P|348|A P|348|S T|347|S T|347|I ACS2 Acetyl CoA Synthetase 683.0 0 0 0 0 -1.4649159094838264 P52910 0.9562489986419678 0.9498909711837769 0.9491789937019348 0.9472420215606691 0.0 0.0 0.07020299136638641 0.4094924032688141 56.98875798774298 50.0 0.0 no 8705 chrXII_446564r 24222 essential YLR153C 989 + TCTATATGGTCCATTAACCT L|331|V silent|CTA>TTA|L|331 ACS2 Acetyl CoA Synthetase 683.0 0 0 0 0 0.2693480135515252 P52910 0.9512209892272948 1.0 46.25884214099205 35.0 0.0 no 8706 chrXII_446578r 24223 essential YLR153C 975 + GGTCACACCTATGCTCTATA H|327|D H|327|Y H|327|Q silent|CAC>CAT|H|327 ACS2 Acetyl CoA Synthetase 683.0 0 0 0 0 -1.0780473698532045 P52910 0.9473130106925964 0.9489949941635132 0.9588389992713928 0.0 0.0 0.0 51.204545555984346 45.0 0.0 no 8707 chrXII_446611r 24225 essential YLR153C 942 + CTCTTCACTGCCGGTGACGT silent|CTC>CTG|L|315 silent|CTC>CTT|L|315 F|316|L silent|TTC>TTT|F|316 ACS2 Acetyl CoA Synthetase 683.0 0 0 0 0 0.5306039499417152 P52910 0.9387490153312684 0.03266534209251404 57.47817436278348 60.0 0.0 no 8708 chrXII_446658 24228 essential YLR153C 898 - AACGTATCTAGTTGTTAAAG V|306|L V|306|I ACS2 Acetyl CoA Synthetase 683.0 0 0 0 0 -1.1267412561201318 P52910 0.9539830088615416 0.9574310183525084 0.09608026593923567 0.2844912707805633 35.80763821182109 30.0 0.0 no 8709 chrXII_446767 24231 essential YLR153C 789 - TCAGCGTCACATGAAACAGG E|270|Q E|270|K A|269|P A|269|T ACS2 Acetyl CoA Synthetase 683.0 0 0 0 0 -4.804122519400286 P52910 0.956179976463318 0.9475290179252625 0.9573720097541808 0.9523990154266356 0.0 0.0 0.04425738006830216 0.0072898687794804564 45.3894893291253 50.0 0.0 yes 8710 chrXII_446820 24233 essential YLR153C 736 - ATGCCACCAGTAATCTCTAC W|251|C W|251|* W|251|S W|251|* ACS2 Acetyl CoA Synthetase 683.0 0 0 0 0 0.6038744706988903 P52910 0.8858469724655151 0.8858469724655151 0.007604951970279217 0.017196089029312134 49.67697887695772 45.0 0.0 no 8711 chrXII_446843r 24235 essential YLR153C 710 + TACTGAAGGTATTCCAATGA T|238|S T|238|I ACS2 Acetyl CoA Synthetase 683.0 0 0 0 0 -0.07884531448677477 P52910 0.9491789937019348 0.9472420215606691 0.9240199327468872 0.1743554025888443 41.21500580221976 35.0 0.0 no 8712 chrXII_447009 24236 essential YLR153C 547 - ACGATCTTTCAACGAACCAG R|189|P R|189|H D|188|H D|188|N ACS2 Acetyl CoA Synthetase 683.0 0 0 0 0 -0.5574400966215437 P52910 0.9099509716033936 0.9570810198783876 0.9486550092697144 0.956179976463318 0.0 0.0 0.04126056656241417 0.24098385870456696 43.3725105464481 45.0 0.0 no 8713 chrXII_447036r 24238 essential YLR153C 517 + TTCACTCTGTTGTCTTTGCT H|174|D H|174|Y H|174|Q silent|CAC>CAT|H|174 ACS2 Acetyl CoA Synthetase 683.0 0 0 0 0 -0.9041767858049878 P52910 0.9473130106925964 0.9489949941635132 0.9588389992713928 0.0 0.0 0.0 51.719750626359094 40.0 0.0 no 8714 chrXII_447199r 24244 essential YLR153C 354 + GACAACAAAATCATCACATT D|119|E silent|GAC>GAT|D|119 N|120|K silent|AAC>AAT|N|120 ACS2 Acetyl CoA Synthetase 683.0 0 0 0 0 1.1552972682624016 P52910 0.9532920122146606 0.9439849853515624 1.0 0.923054337501526 35.34086090898171 30.0 0.0 no 8715 chrXII_447352r 24246 essential YLR153C 201 + CCATACACCAAAGTTCAATC P|68|R P|68|L Y|69|* silent|TAC>TAT|Y|69 ACS2 Acetyl CoA Synthetase 683.0 0 0 0 0 -0.09516267629789732 P52910 0.9432820081710817 0.9430609941482544 0.2169219255447388 0.16218958795070648 42.85981270192673 40.0 0.0 no 8716 chrXII_447381r 24248 essential YLR153C 172 + TGGCTAAGGAATACTTGCAT A|59|G A|59|V ACS2 Acetyl CoA Synthetase 683.0 0 0 0 0 -0.4940712723665788 P52910 0.9484469890594482 0.9504740238189696 0.2555935978889465 0.004868461284786464 44.097787816151936 40.0 0.0 no 8717 chrXII_447403 24250 essential YLR153C 153 - ATCTTATCAAAGAATTTTTC K|57|N silent|AAG>AAA|K|57 ACS2 Acetyl CoA Synthetase 683.0 0 0 0 0 0.6610840291956515 P52910 0.9355990290641784 0.2872757613658905 32.77341526901557 20.0 0.0 no 8718 chrXII_447469 24252 essential YLR153C 87 - TCAGTAACGTAACCCTTGCC D|36|H D|36|N ACS2 Acetyl CoA Synthetase 683.0 0 0 0 0 -1.7663544087330771 P52910 0.9486550092697144 0.956179976463318 0.10721436142921448 0.6966624855995178 51.43130379820423 50.0 0.0 no 8719 chrXII_447473 24253 essential YLR153C 83 - TAACGTAACCCTTGCCGGGT V|34|L V|34|I ACS2 Acetyl CoA Synthetase 683.0 0 0 0 0 -1.8515018755638684 P52910 0.9539830088615416 0.9574310183525084 0.4023991823196411 1.0 54.30413152190136 55.00000000000001 0.0 no 8720 chrXII_447481r 24254 essential YLR153C 72 + TACAACAGCCAACCCGGCAA Y|25|* silent|TAC>TAT|Y|25 N|26|K silent|AAC>AAT|N|26 ACS2 Acetyl CoA Synthetase 683.0 0 0 0 0 -2.525152658955031 P52910 0.9439849853515624 0.917607605457306 52.012215048217506 55.00000000000001 0.0 yes 8721 chrXII_447482r 24255 essential YLR153C 71 + TTACAACAGCCAACCCGGCA Y|25|* silent|TAC>TAT|Y|25 N|26|K silent|AAC>AAT|N|26 ACS2 Acetyl CoA Synthetase 683.0 0 0 0 0 -4.073119020612795 P52910 0.9439849853515624 0.917607605457306 53.77043388665129 55.00000000000001 0.0 yes 8722 chrXII_492245r 24257 essential YLR163C 987 + TACGCTGATTCAGGTCTGTG Y|330|* silent|TAC>TAT|Y|330 A|331|G A|331|V MAS1 Mitochondrial ASsembly 462.0 0 0 0 0 -0.5708706727120701 P10507 0.842402994632721 0.8539289832115173 0.25059014558792114 0.27114084362983704 1.1604059934616089 -0.7895159721374512 0.879800021648407 0.5947200059890747 50.11656703633787 50.0 0.0 no 8723 chrXII_492253 24259 essential YLR163C 982 - ACCTGAATCAGCGTAAGAGG G|334|R G|334|S G|334|A G|334|D MAS1 Mitochondrial ASsembly 462.0 0 0 0 0 -5.483283265119555 P10507 0.5165429711341858 0.800616979598999 0.7633910179138184 0.5424919724464417 0.0 0.0 0.0 0.0 22.644126892089844 9.170598030090332 5.413549900054932 19.130168914794922 46.357085831208 50.0 0.0 yes 8724 chrXII_492254r 24260 essential YLR163C 978 + TCCACCTCTTACGCTGATTC silent|TCC>TCG|S|327 silent|TCC>TCT|S|327 S|327|C S|327|F MAS1 Mitochondrial ASsembly 462.0 0 0 0 0 -0.05557110144962385 P10507 0.7427719831466675 0.7423210144042969 0.00782988965511322 0.01732226088643074 -1.058102011680603 3.8069679737091056 -0.8855000138282776 3.4706599712371826 53.53323664955253 50.0 0.0 no 8725 chrXII_492311 24261 essential YLR163C 924 - TGACTTGCTGCAACAGCTAA S|314|T S|314|N MAS1 Mitochondrial ASsembly 462.0 0 0 0 0 0.28401802620932204 P10507 0.9480609893798828 0.928620994091034 0.14343973994255066 0.008114160038530827 1.312384009361267 0.6986160278320312 47.01584731474839 45.0 0.0 no 8726 chrXII_492318 24263 essential YLR163C 917 - CTGCAACAGCTAATGGAGAG A|312|P A|312|T V|311|L V|311|I MAS1 Mitochondrial ASsembly 462.0 0 0 0 0 0.8539004947764651 P10507 0.7521169781684875 0.8873289823532104 0.8989859819412231 0.8958899974822998 0.37369176745414734 0.751224160194397 0.5311313867568971 0.32770204544067383 3.285288095474243 1.1560280323028564 -0.888808012008667 -0.8270499706268309 3.4837000370025635 0.7771199941635132 -0.8529800176620483 -0.8440600037574768 44.62749060011549 50.0 0.0 no 8727 chrXII_492370r 24265 essential YLR163C 862 + CACAAGCGATTGTTGGTAAC Q|289|E Q|289|* A|290|G A|290|V MAS1 Mitochondrial ASsembly 462.0 0 0 0 0 -1.358399061664581 P10507 0.7511280179023743 0.7734410166740417 0.6854450106620789 0.1075986698269844 0.017243999987840652 0.02470727078616619 1.110103964805603 1.8219799995422363 -0.6846320033073425 1.6281399726867676 -1.119760036468506 0.6574599742889404 43.31006256305426 45.0 0.0 no 8728 chrXII_492494 24269 essential YLR163C 741 - CCTCTACAAAAAACTGGTAA R|253|T R|253|K G|254|R G|254|S MAS1 Mitochondrial ASsembly 462.0 0 0 0 0 -0.2510402545290915 P10507 0.9348919987678528 0.9278550148010254 0.8682389855384827 0.9690409898757936 0.018652718514204025 0.03705820068717003 0.036454599350690835 1.0 -0.006812000181525946 0.15573999285697934 3.4925899505615234 3.1994259357452397 37.336260443142855 35.0 0.0 no 8729 chrXII_492530r 24272 essential YLR163C 702 + TCTGAATCGCCTGTCCCGTT S|235|C S|235|F MAS1 Mitochondrial ASsembly 462.0 1 Series([], Name: modification, dtype: object) 0 0 0 1.385553212722214 P10507 0.8900880217552185 0.8770999908447266 0.0477726049721241 0.07278057187795639 0.3795099854469299 -0.0011620000004768374 57.699378684624826 55.00000000000001 0.0 no 8730 chrXII_492543 24274 essential YLR163C 692 - GCGATTCAGATTTGGGCACA silent|TCG>TCC|S|237 silent|TCG>TCA|S|237 E|236|Q E|236|K MAS1 Mitochondrial ASsembly 462.0 0 0 0 1 0.9438797448411846 P10507 0.9692280292510986 0.9500370025634766 0.5851192474365234 0.8658283352851868 -0.09240800142288208 -0.07586999982595444 51.103038098943216 50.0 0.0 no 8731 chrXII_492634 24277 essential YLR163C 601 - TCTGTCGCCTTTATAGTTCT R|207|T R|207|K D|206|H D|206|N MAS1 Mitochondrial ASsembly 462.0 0 1 0 0 0.30570812797550506 P10507 0.5838800072669983 0.7296820282936096 0.789264976978302 0.8416979908943176 0.00271046906709671 0.041337400674819946 0.21074329316616056 0.4165720641613007 2.1225779056549072 0.4962620139122009 0.9672080278396606 0.10444600135087967 51.609714483208506 40.0 0.0 no 8732 chrXII_492710 24278 essential YLR163C 525 - CCCAGAATGGTTCTTCCTAA silent|CTG>CTC|L|181 silent|CTG>CTA|L|181 G|182|R G|182|S MAS1 Mitochondrial ASsembly 462.0 0 0 0 1 -0.021599907678850075 P10507 0.5858960151672363 0.6784449815750122 0.0 0.0 22.19137191772461 9.983798027038574 50.56629865529232 45.0 0.0 no 8733 chrXII_492711r 24279 essential YLR163C 521 + ACCTTTAGGAAGAACCATTC P|175|R P|175|L P|175|A P|175|S MAS1 Mitochondrial ASsembly 462.0 0 0 0 0 -1.6810824495971917 P10507 0.7720959782600403 0.7827839851379395 0.9620479941368104 0.9469010233879088 0.004051229916512965 0.00554614095017314 0.30432671308517456 0.3240615725517273 1.393929958343506 1.4196159839630127 1.5348080396652222 1.7614059448242188 44.06372721903404 40.0 0.0 no 8734 chrXII_492725r 24280 essential YLR163C 507 + ACGTATAAGGACCAACCTTT T|170|R T|170|M MAS1 Mitochondrial ASsembly 462.0 0 0 0 0 -0.2448534445739777 P10507 0.7847129702568054 0.7353730201721191 0.0012330912286415696 0.0016836569411680102 6.308177947998048 0.8941159844398499 45.127663964057035 40.0 0.0 no 8735 chrXII_492738r 24281 essential YLR163C 494 + TCTTCATGAGATTACGTATA L|166|V L|166|F H|167|D H|167|Y MAS1 Mitochondrial ASsembly 462.0 0 0 0 0 -1.1846723021368577 P10507 0.8316109776496887 0.8403109908103943 0.5964509844779968 0.6047260165214539 0.0 0.0 0.0 0.0 2.445810079574585 3.2309598922729488 2.679919958114624 1.990079998970032 2.7573399543762207 0.919099986553192 39.74899491526856 30.0 0.0 no 8736 chrXII_493020r 24284 essential YLR163C 212 + TCTAGAACACTTGGCTTTCA L|72|V silent|CTA>TTA|L|72 MAS1 Mitochondrial ASsembly 462.0 0 1 0 0 0.07492151441238826 P10507 0.8801519870758057 0.07113785296678543 1.801740050315857 46.246326197871504 40.0 0.0 no 8737 chrXII_493103r 24286 essential YLR163C 129 + AACACATCTTCGGCTACTGT N|44|K silent|AAC>AAT|N|44 T|45|R T|45|I MAS1 Mitochondrial ASsembly 462.0 0 0 0 0 0.5253177255619224 P10507 0.8878200054168701 0.8672890067100525 0.8793960213661194 0.3002984821796417 0.4015828967094421 0.3450934290885925 -0.07943200320005417 0.4919779896736145 1.1937479972839355 0.1500599980354309 -1.4810400009155271 1.1720000505447388 48.575989984415685 45.0 0.0 no 8738 chrXII_493150 24289 essential YLR163C 85 - CAACCCATTAGGAAGTTTAG silent|GGG>GGC|G|34 silent|GGG>GGA|G|34 G|34|A G|34|E MAS1 Mitochondrial ASsembly 462.0 0 0 0 0 -5.745825495022901 P10507 0.6929159760475159 0.6268079876899719 0.015619061887264253 0.00455619627609849 7.06657600402832 10.39465045928955 42.994522615141534 40.0 0.0 yes 8739 chrXII_493153r 24290 essential YLR163C 79 + GAACCTCTAAACTTCCTAAT T|28|S T|28|I silent|ACC>ACG|T|28 silent|ACC>ACT|T|28 MAS1 Mitochondrial ASsembly 462.0 0 0 0 0 -0.07793663663667698 P10507 0.9373660087585448 0.9447900056838988 0.040496136993169785 0.24589180946350095 0.618478000164032 -1.062291979789734 41.56444678571381 35.0 0.0 no 8740 chrXII_493174 24291 essential YLR163C 61 - TCTGGTTCCTGGAATTTGTG R|27|T R|27|K MAS1 Mitochondrial ASsembly 462.0 0 0 0 0 -1.0313431305942589 P10507 0.9069390296936036 0.9631270170211792 0.2108171433210373 0.4598492383956909 1.28616201877594 0.03624200075864792 49.11892537753721 45.0 0.0 no 8741 chrXII_493181r 24292 essential YLR163C 51 + ACAATTTCCTCACAAATTCC T|18|R T|18|I MAS1 Mitochondrial ASsembly 462.0 0 0 0 0 0.4682417057841076 P10507 0.9688799977302552 0.9562690258026124 0.5266504287719727 0.21017757058143616 42.831710473186774 35.0 0.0 no 8742 chrXII_493216r 24295 essential YLR163C 16 + CATCCAAGTTCCGTAATACA S|7|C S|7|F silent|TCC>TCG|S|7 silent|TCC>TCT|S|7 MAS1 Mitochondrial ASsembly 462.0 0 0 0 0 0.029425639658146457 P10507 0.9534749984741212 0.9526699781417848 0.03837389498949051 0.03935342654585838 45.644790048904326 40.0 0.0 no 8743 chrXII_496173r 24296 essential YLR166C 1849 + TTGCGTTAGAAGTCGCTTAC A|618|G A|618|V SEC10 SECretory 871.0 0 0 0 0 -1.830117736167899 Q06245 0.9484469890594482 0.9504740238189696 0.6736776828765869 0.04944799467921257 46.768561557058774 45.0 0.0 no 8744 chrXII_496400r 24298 essential YLR166C 1622 + AGCAAACAACTCTTCAAGTT A|542|G A|542|V N|543|K silent|AAC>AAT|N|543 SEC10 SECretory 871.0 0 0 0 0 0.6431407408124521 Q06245 0.9484469890594482 0.9504740238189696 0.9439849853515624 40.49750072271155 35.0 0.0 no 8745 chrXII_496582r 24301 essential YLR166C 1440 + GCATTCATGCATTCTCCTAG A|481|G A|481|V F|482|L silent|TTC>TTT|F|482 SEC10 SECretory 871.0 0 1 0 0 0.3508713439411164 Q06245 0.9484469890594482 0.9504740238189696 0.9387490153312684 0.3746855556964874 0.3052352964878082 0.8282386064529419 51.23258575704721 45.0 0.0 no 8746 chrXII_496668 24302 essential YLR166C 1357 - ATCATAGTTTACAGTAAACT D|459|H D|459|N SEC10 SECretory 871.0 0 0 0 0 0.7496859144278911 Q06245 0.9486550092697144 0.956179976463318 0.030869195237755775 0.3712382018566132 36.32289487417563 25.0 0.0 no 8747 chrXII_496749r 24303 essential YLR166C 1273 + TTTCGCATTATCTATATGAT S|426|W S|426|L H|427|D H|427|Y SEC10 SECretory 871.0 0 0 0 0 -0.0006923414372869557 Q06245 0.9288619756698608 0.9298099875450134 0.9473130106925964 0.9489949941635132 0.033575449138879776 0.22963324189186096 0.6079033017158508 0.03893095254898071 39.50709982010432 25.0 0.0 no 8748 chrXII_496939 24305 essential YLR166C 1086 - CTCAATAAAACCTCAAATCT L|368|F silent|TTG>TTA|L|368 SEC10 SECretory 871.0 0 0 0 0 0.4621044946100028 Q06245 0.9587849974632264 0.0 35.92566505378278 30.0 0.0 no 8749 chrXII_497073 24306 essential YLR166C 952 - ATCATTTATCAAATTTTGCA D|324|H D|324|N SEC10 SECretory 871.0 0 0 0 0 0.06426247742186747 Q06245 0.9486550092697144 0.956179976463318 0.14750534296035767 0.4824727475643158 36.60566094314015 20.0 0.0 no 8750 chrXII_497505 24308 essential YLR166C 520 - AACAATATCTGATTTTCCCA V|180|L V|180|I SEC10 SECretory 871.0 0 0 0 0 0.4914875005659751 Q06245 0.9539830088615416 0.9574310183525084 1.0 0.0823780968785286 42.27348086071414 30.0 0.0 no 8751 chrXII_497612r 24311 essential YLR166C 410 + TACTCAAGTTGTTTCGCCAT T|138|S T|138|I Q|139|E Q|139|* SEC10 SECretory 871.0 0 1 0 0 0.5723372304107175 Q06245 0.9491789937019348 0.9472420215606691 0.9590039849281312 0.5851068496704102 0.024788135662674904 0.22813184559345245 48.64291607342562 40.0 0.0 no 8752 chrXII_497714r 24312 essential YLR166C 308 + TACTCAGGAAGTTATTCATT T|104|S T|104|I Q|105|E Q|105|* SEC10 SECretory 871.0 0 0 0 0 -0.7577501863717842 Q06245 0.9491789937019348 0.9472420215606691 0.9590039849281312 0.6708757877349854 0.14439557492733002 0.235425665974617 40.27673018013014 30.0 0.0 no 8753 chrXII_497798r 24313 essential YLR166C 224 + AACTTTTGAATCTACCTTAA T|76|S T|76|I SEC10 SECretory 871.0 0 0 0 0 0.8153551141314891 Q06245 0.9491789937019348 0.9472420215606691 0.0 0.0 37.36576089351019 25.0 0.0 no 8754 chrXII_497738r 24314 essential YLR166C 284 + ACAGTATTTTTCCGAGCAAG Q|96|E Q|96|* SEC10 SECretory 871.0 0 0 0 0 0.6793768528321324 Q06245 0.9590039849281312 1.0 44.88755033239147 40.0 0.0 no 8755 chrXII_497868 24315 essential YLR166C 157 - TGCATCCTGATCCTTTTCAT A|59|P A|59|T D|58|H D|58|N SEC10 SECretory 871.0 0 0 0 0 0.535498943749807 Q06245 0.9573720097541808 0.9523990154266356 0.9486550092697144 0.956179976463318 51.892075806406744 40.0 0.0 no 8756 chrXII_497872 24316 essential YLR166C 153 - TCCTGATCCTTTTCATTGGT Q|57|H silent|CAG>CAA|Q|57 D|58|H D|58|N SEC10 SECretory 871.0 0 0 0 0 -0.8657223900843071 Q06245 0.9570760130882264 0.9486550092697144 0.956179976463318 52.30404002926053 40.0 0.0 no 8757 chrXII_497951r 24317 essential YLR166C 71 + AACAGTCAATGAATTCGTTC T|25|R T|25|I silent|GTC>GTG|V|26 silent|GTC>GTT|V|26 SEC10 SECretory 871.0 0 0 0 0 -0.5122371941013455 Q06245 0.9476869702339172 0.9472420215606691 0.009834920987486841 0.010656251572072506 38.879445264929814 35.0 0.0 no 8758 chrXII_497998 24318 essential YLR166C 27 - TTCAATAGTTTCTTCCATTT L|15|F silent|TTG>TTA|L|15 SEC10 SECretory 871.0 0 0 0 0 0.04884018753745466 Q06245 0.9587849974632264 0.0 42.43003582842431 25.0 0.0 no 8759 chrXII_499216 24322 essential YLR167W 254 + GATCAAGCACAAGCACAAGA error error RPS31 Ribosomal Protein of the Small subunit 152.0 0 0 0 0 -0.7794474248015306 P05759 43.07208002030279 45.0 1.0 no 8760 chrXII_499246 24323 essential YLR167W 284 + GGCTGTCTTGTCCTACTACA error error error error RPS31 Ribosomal Protein of the Small subunit 152.0 0 0 0 0 0.2342310272608477 P05759 55.578957315726434 50.0 1.0 no 8761 chrXII_499257r 24324 essential YLR167W 298 - TTCAGCATCGACCTTGTAGT error error error error RPS31 Ribosomal Protein of the Small subunit 152.0 0 0 0 0 -0.18951567641738085 P05759 51.40294036984118 45.0 1.0 no 8762 chrXII_499259 24325 essential YLR167W 297 + TACTACAAGGTCGATGCTGA error error error error RPS31 Ribosomal Protein of the Small subunit 152.0 0 0 0 0 -0.10418424992810188 P05759 45.67929658996736 45.0 1.0 no 8763 chrXII_506180r 24327 essential YLR175W 49 - TGGCCATTCACTAGTGTCAG W|22|C W|22|* W|22|S W|22|* CBF5 Centromere Binding Factor 483.0 0 0 0 0 -1.070512144514069 P33322 0.8858469724655151 0.8858469724655151 0.0 0.0 3.1738200187683105 3.7409799098968506 1.7570199966430664 2.3489398956298833 52.682414371605894 50.0 1.0 no 8764 chrXII_506340r 24328 essential YLR175W 209 - CTACAACTTCGTGCGATGAT V|76|L V|76|I V|75|L V|75|I CBF5 Centromere Binding Factor 483.0 0 1 0 0 -0.10376338020970582 P33322 0.9539830088615416 0.9574310183525084 0.9539830088615416 0.9574310183525084 0.012479806318879128 0.015126007609069347 0.008743332698941229 0.11690019816160202 0.4528000056743622 1.152899980545044 1.114799976348877 -0.4375799894332886 0.5773400068283081 0.2814399898052216 0.21714000403881076 -0.5593400001525879 45.22962186529338 45.0 1.0 no 8765 chrXII_506341r 24329 essential YLR175W 210 - GCTACAACTTCGTGCGATGA A|77|P A|77|T V|76|L V|76|I CBF5 Centromere Binding Factor 483.0 0 1 0 0 -4.472680019451968 P33322 0.9573720097541808 0.9523990154266356 0.9539830088615416 0.9574310183525084 0.013442091643810272 0.1584702730178833 0.012479806318879128 0.015126007609069347 3.559900045394897 1.3103200197219849 0.4528000056743622 1.152899980545044 4.740640163421631 0.984660029411316 0.5773400068283081 0.2814399898052216 48.701262275602744 50.0 1.0 yes 8766 chrXII_506410 24332 essential YLR175W 276 + ACATTGGATCCAAAAGTTAC T|93|R T|93|I CBF5 Centromere Binding Factor 483.0 0 1 0 0 -1.8228666546945331 P33322 0.9476869702339172 0.9472420215606691 0.001075158128514886 0.0012072531972080471 0.0936800017952919 -0.6128000020980835 39.41741754045961 35.0 1.0 no 8767 chrXII_506419r 24333 essential YLR175W 288 - ATCAAACAACCTGTAACTTT L|102|F silent|TTG>TTA|L|102 C|101|S C|101|Y CBF5 Centromere Binding Factor 483.0 0 0 0 0 0.4760218279447211 P33322 0.9587849974632264 0.9421560168266296 0.9290120005607604 0.0 0.0817895457148552 0.06849367171525955 9.69066047668457 1.385200023651123 18.82391929626465 0.6681600213050842 15.01233959197998 38.54039008863765 30.0 1.0 no 8768 chrXII_506554 24335 essential YLR175W 420 + CGCTCACTAGAAAACTTGAC silent|CGC>CGG|R|141 silent|CGC>CGT|R|141 S|142|* S|142|L CBF5 Centromere Binding Factor 483.0 0 0 0 0 0.26947690980811045 P33322 0.9298099875450134 0.11253291368484496 0.2954599857330322 41.09135255477196 45.0 1.0 no 8769 chrXII_506662 24336 essential YLR175W 528 + TTCGATAACAAGAGAAACTT F|177|L silent|TTC>TTT|F|177 CBF5 Centromere Binding Factor 483.0 0 1 0 0 -0.7275648096939339 P33322 0.9387490153312684 0.18352526426315308 1.6210600137710571 -0.19043999910354611 1.700899958610535 34.169732594394304 30.0 1.0 no 8770 chrXII_506734 24338 essential YLR175W 600 + GTTCATTTAGGTATGCTATT H|202|D H|202|Y CBF5 Centromere Binding Factor 483.0 0 0 0 0 -1.2009695544711676 P33322 0.9473130106925964 0.9489949941635132 0.5979132652282715 0.01950821094214916 1.6079200506210327 -0.2504599988460541 43.79961581069415 30.0 1.0 no 8771 chrXII_506823 24340 essential YLR175W 689 + GGTCACTTTACATGATGTTA silent|GTC>GTG|V|231 silent|GTC>GTT|V|231 T|232|S T|232|I CBF5 Centromere Binding Factor 483.0 0 0 0 0 -0.3167270157203912 P33322 0.9491789937019348 0.9472420215606691 0.01511689927428961 0.0028896431904286146 -0.6409599781036377 1.0958600044250488 -0.3098999857902527 0.5036399960517883 43.818637435565336 35.0 1.0 no 8772 chrXII_506901 24341 essential YLR175W 767 + TCAACCTTTAGAAACTCTAT Q|257|E Q|257|* P|258|A P|258|S CBF5 Centromere Binding Factor 483.0 0 0 0 0 -0.5837069659156158 P33322 0.9590039849281312 0.9562489986419678 0.9498909711837769 0.2775923609733581 0.0 0.0 0.6585000157356262 2.737459897994995 4.606579780578613 -0.8420467376708984 -1.0674200057983398 39.02757764027536 30.0 1.0 no 8773 chrXII_506905r 24343 essential YLR175W 774 - CCAACCAATAGAGTTTCTAA G|265|R G|265|S V|264|L V|264|I CBF5 Centromere Binding Factor 483.0 0 1 0 0 -0.9759253872009692 P33322 0.941340982913971 0.951104998588562 0.9539830088615416 0.9574310183525084 0.2358512133359909 0.8718772530555725 0.1396976262331009 0.15277381241321564 -0.7842599749565125 -0.17635999619960785 -1.2110799551010132 -0.4747399985790253 -1.2396199703216553 -0.968999981880188 -1.1415599584579468 -0.00855332612991333 41.65864329779357 35.0 1.0 no 8774 chrXII_506994r 24346 essential YLR175W 863 - CTTCGTAACGCAATAAACCA E|294|Q E|294|K CBF5 Centromere Binding Factor 483.0 0 0 0 0 -0.4079828248026989 P33322 0.956179976463318 0.9475290179252625 0.014541451819241047 0.01510773226618767 2.1470000743865967 2.8117799758911133 1.8362200260162356 3.6440200805664062 41.57777158113868 40.0 1.0 no 8775 chrXII_506995r 24347 essential YLR175W 864 - TCTTCGTAACGCAATAAACC E|295|Q E|295|K E|294|Q E|294|K CBF5 Centromere Binding Factor 483.0 0 0 0 0 0.5823884895782121 P33322 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.5822682380676271 0.9211900234222412 0.014541451819241047 0.01510773226618767 0.061039999127388 0.0020200000144541264 2.1470000743865967 2.8117799758911133 -0.045770004391670234 0.07875999808311462 1.8362200260162356 3.6440200805664062 41.21247925147264 40.0 1.0 no 8776 chrXII_507056r 24348 essential YLR175W 925 - AACGGCAATGGCTTCACCCT V|315|L V|315|I A|314|P A|314|T CBF5 Centromere Binding Factor 483.0 0 0 0 0 -0.8977209006331361 P33322 0.9539830088615416 0.9574310183525084 0.9573720097541808 0.9523990154266356 1.0 0.8559818267822266 0.012442713603377342 0.00859368871897459 -1.00927996635437 -1.0455399751663208 5.008180141448975 2.0246400833129883 4.290380001068115 5.8659400939941415 0.19279000163078308 -1.3304799795150757 54.622046737240616 55.00000000000001 1.0 no 8777 chrXII_507074r 24349 essential YLR175W 943 - TGACATTTGTGCGATGGCAA M|320|I M|320|I CBF5 Centromere Binding Factor 483.0 0 0 0 0 0.0035114838944846354 P33322 0.9553959965705872 0.9553959965705872 0.0138617604970932 0.0138617604970932 1.4211000204086304 1.4211000204086304 0.9103800058364868 0.9103800058364868 47.01935992324343 45.0 1.0 no 8778 chrXII_507103 24352 essential YLR175W 969 + GACTTAGCTTCCTGTGATCA D|324|E silent|GAC>GAT|D|324 CBF5 Centromere Binding Factor 483.0 0 0 0 0 0.6313473206641272 P33322 0.9532920122146606 1.0 0.2306800037622452 51.26155131055896 45.0 1.0 no 8779 chrXII_507172r 24355 essential YLR175W 1041 - GGACCCAAACCCCATCTTCT G|353|A G|353|D G|353|R G|353|S CBF5 Centromere Binding Factor 483.0 0 0 0 0 0.04982650917953388 P33322 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.05428609251976013 0.003488101763650775 0.00258800876326859 0.012538813054561615 57.140519873048795 55.00000000000001 1.0 no 8780 chrXII_507193r 24356 essential YLR175W 1062 - TGCTTCTTCTTTTGTGCGAC K|360|N silent|AAG>AAA|K|360 K|359|N silent|AAG>AAA|K|359 CBF5 Centromere Binding Factor 483.0 0 0 0 0 0.9389446747728454 P33322 0.9355990290641784 0.9355990290641784 0.052314132452011115 0.004400735255330801 0.5509200096130371 50.959181581269895 45.0 1.0 no 8781 chrXII_523660r 24358 essential YLR186W 31 - CTTCTGATCACCACCTTTGA Q|16|H silent|CAG>CAA|Q|16 EMG1 Essential for Mitotic Growth 252.0 0 0 0 0 -1.3191052868193205 Q06287 51.02824521609063 45.0 1.0 no 8782 chrXII_523661r 24359 essential YLR186W 32 - CCTTCTGATCACCACCTTTG K|17|N silent|AAG>AAA|K|17 Q|16|H silent|CAG>CAA|Q|16 EMG1 Essential for Mitotic Growth 252.0 0 0 0 0 0.1984637375909992 Q06287 53.49959665296933 50.0 1.0 no 8783 chrXII_523712 24360 essential YLR186W 80 + ACCTCCTGTCTTGACATCAA P|28|R P|28|L P|28|A P|28|S EMG1 Essential for Mitotic Growth 252.0 0 0 0 0 -0.15120238958043347 Q06287 0.1029735803604126 0.26337873935699463 0.5417450070381165 0.09231989830732346 -1.4096200466156006 -0.3266600072383881 -0.16680000722408295 -0.4029400050640106 51.34245304599693 45.0 1.0 no 8784 chrXII_523661 24362 essential YLR186W 29 + CCTCAAAGGTGGTGATCAGA silent|CTC>CTG|L|11 silent|CTC>CTT|L|11 L|11|V L|11|F EMG1 Essential for Mitotic Growth 252.0 0 0 0 1 0.2468522984776093 Q06287 48.833964922229306 50.0 1.0 no 8785 chrXII_523786 24363 essential YLR186W 154 + CACACAAGATATCGTCCAAC H|53|D H|53|Y H|53|Q silent|CAC>CAT|H|53 EMG1 Essential for Mitotic Growth 252.0 0 0 0 0 -0.3161783699913973 Q06287 0.17991545796394348 1.0 0.2570036053657532 1.3009599447250366 -1.710379958152771 -0.2322400063276291 1.3444199562072754 -1.45386004447937 0.12343999743461607 43.14943760671389 45.0 1.0 no 8786 chrXII_523906r 24365 essential YLR186W 277 - CAACGTCAAAAGACATTGGT silent|ACG>ACC|T|98 silent|ACG>ACA|T|98 L|97|F silent|TTG>TTA|L|97 EMG1 Essential for Mitotic Growth 252.0 0 0 0 0 -0.6756414317646702 Q06287 0.006472230423241854 4.9070401191711435 1.5795199871063232 4.701819896697998 39.6274519394388 40.0 1.0 no 8787 chrXII_523938r 24366 essential YLR186W 309 - AGCTTTCCGGCTTTGTTGAT K|109|N silent|AAG>AAA|K|109 G|108|A G|108|E EMG1 Essential for Mitotic Growth 252.0 0 0 0 0 0.036474383141938516 Q06287 0.16547051072120667 0.006020317319780588 0.003935970366001129 0.6642799973487854 2.1223599910736084 6.44980001449585 53.89348688834946 45.0 1.0 no 8788 chrXII_524006r 24369 essential YLR186W 377 - TTCTTGGTATACGAACAGTG R|132|T R|132|K EMG1 Essential for Mitotic Growth 252.0 0 0 0 0 -0.5858578554110024 Q06287 0.0 0.0 0.5127400159835815 0.14791999757289884 0.1350799947977066 -0.0790800005197525 0.906220018863678 0.3248099982738495 42.06877019361053 40.0 1.0 no 8789 chrXII_524066 24371 essential YLR186W 434 + ACATAAGCTTTCTATCAGAT H|146|D H|146|Y EMG1 Essential for Mitotic Growth 252.0 0 1 0 0 0.11882963197286744 Q06287 0.0782025158405304 0.007924274541437626 1.9627200365066528 1.2968000173568726 0.8337200284004211 0.4277800023555756 40.63239818259615 30.0 1.0 no 8790 chrXII_524141 24373 essential YLR186W 509 + CCTACCTACTAAGTGCCGTA L|171|V silent|CTA>TTA|L|171 P|172|A P|172|S EMG1 Essential for Mitotic Growth 252.0 0 0 0 0 0.2461386740281801 Q06287 0.014770579524338244 0.012525133788585665 0.006731689441949129 2.2016398906707764 2.372999906539917 3.095160007476806 2.1282799243926998 52.94224691889775 50.0 1.0 no 8791 chrXII_524145r 24375 essential YLR186W 516 - GTCACCTTACGGCACTTAGT silent|GTG>GTC|V|178 silent|GTG>GTA|V|178 V|178|L V|178|M EMG1 Essential for Mitotic Growth 252.0 0 0 0 0 -1.0027972497051143 Q06287 0.10090062767267227 0.007968268357217312 -0.03548000007867813 2.152559995651245 53.6732539602761 50.0 1.0 no 8792 chrXII_542275r 24379 essential YLR195C 1007 + CCTAAATAACACAAAATATA L|337|V silent|CTA>TTA|L|337 NMT1 N-Myristoyl Transferase 455.0 0 0 0 0 0.30363658611134475 P14743 0.2477593272924423 1.3444199562072754 1.387719988822937 29.70097073006036 20.0 0.0 no 8793 chrXII_542275 24380 essential YLR195C 1010 - CCTTATATTTTGTGTTATTT K|343|N silent|AAG>AAA|K|343 NMT1 N-Myristoyl Transferase 455.0 0 0 0 0 0.8055445921769571 P14743 0.5734421014785767 0.018300000578165054 -0.024119999259710312 39.88513578216885 20.0 0.0 no 8794 chrXII_542571 24384 essential YLR195C 714 - TCCTCCTCTGTGTGCCCATC E|244|D silent|GAG>GAA|E|244 D|245|H D|245|N NMT1 N-Myristoyl Transferase 455.0 0 0 0 0 -1.0646320400971023 P14743 0.19170598685741425 0.07884948700666428 0.0587901882827282 0.4501399993896485 1.949280023574829 1.550179958343506 64.91844338205988 60.0 0.0 no 8795 chrXII_542627r 24386 essential YLR195C 655 + ATACTCATCGTCCCTTGAAT T|220|S T|220|I H|221|D H|221|Y NMT1 N-Myristoyl Transferase 455.0 0 0 0 0 -0.021973419927147717 P14743 0.00407444080337882 0.010958311147987844 0.0 0.0 -0.12464000284671785 0.7765399813652039 0.5386199951171875 -1.6771800518035889 48.28252538360789 40.0 0.0 no 8796 chrXII_542652 24387 essential YLR195C 633 - CGACACGTACTCACAGGTGC C|217|S C|217|Y silent|ACG>ACC|T|216 silent|ACG>ACA|T|216 NMT1 N-Myristoyl Transferase 455.0 0 0 0 0 -0.32829139511143496 P14743 0.060915127396583564 0.0010047752875834703 0.3405399918556213 24.08230018615723 51.856691067569045 60.0 0.0 no 8797 chrXII_542689r 24389 essential YLR195C 593 + CATCTGGCATGCATTGTACA I|199|M silent|ATC>ATT|I|199 NMT1 N-Myristoyl Transferase 455.0 0 0 0 0 0.11854787991660401 P14743 0.006053550634533167 0.2948800027370453 0.10648000240325928 49.738540670757686 45.0 0.0 no 8798 chrXII_542831 24391 essential YLR195C 454 - AACACCAAGTGTTACTGGTA V|158|L V|158|I G|157|A G|157|D NMT1 N-Myristoyl Transferase 455.0 0 0 0 0 0.21557608789460514 P14743 0.07391878962516785 0.15652692317962644 0.07280489057302475 0.1510019451379776 -1.262220025062561 -1.0339800119400024 0.28610000014305115 1.8507200479507449 44.98444617261157 40.0 0.0 no 8799 chrXII_542835r 24393 essential YLR195C 447 + TCAGCCATACCAGTAACACT S|150|* S|150|L A|151|G A|151|V NMT1 N-Myristoyl Transferase 455.0 0 0 0 0 -1.5338501487886274 P14743 0.01009295228868723 1.0 0.010973996482789516 -0.7329999804496765 2.109100103378296 -0.6821200251579285 0.6820399761199951 0.10196000337600708 49.90311709530396 45.0 0.0 no 8800 chrXII_543090 24399 essential YLR195C 195 - GGCTTGTCAGATATATCTTC K|71|N silent|AAG>AAA|K|71 NMT1 N-Myristoyl Transferase 455.0 0 0 0 0 1.0291911007450458 P14743 0.17307186126708984 0.31435999274253845 46.559863262776325 40.0 0.0 no 8801 chrXII_544060 24401 essential YLR196W 92 + CCAATTAGCACAGTTGAATT Q|32|E Q|32|* PWP1 Periodic tryptophan (W) Protein 576.0 0 0 0 0 0.2415522921825787 P21304 0.9590039849281312 0.7954707145690918 42.21722647426492 35.0 1.0 no 8802 chrXII_544060r 24402 essential YLR196W 95 - CCAAATTCAACTGTGCTAAT L|38|F silent|TTG>TTA|L|38 PWP1 Periodic tryptophan (W) Protein 576.0 0 0 0 0 0.13066179312710116 P21304 0.9587849974632264 0.14823618531227112 40.85350555478272 35.0 1.0 no 8803 chrXII_544289 24406 essential YLR196W 321 + AGCGATGTTAAATTCCATGA S|108|R silent|AGC>AGT|S|108 PWP1 Periodic tryptophan (W) Protein 576.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.7667007306864648 P21304 0.9417110085487366 0.2512166202068329 42.29593521673729 35.0 1.0 no 8804 chrXII_544395r 24407 essential YLR196W 430 - CGCAGCAAGAACTAAATTAT A|150|P A|150|T A|149|P A|149|T PWP1 Periodic tryptophan (W) Protein 576.0 0 0 0 0 -0.06685900887561026 P21304 0.9573720097541808 0.9523990154266356 0.9573720097541808 0.9523990154266356 0.017211984843015667 0.2272093296051025 0.022064944729208943 0.3883993029594421 37.82949459187996 35.0 1.0 no 8805 chrXII_544451 24408 essential YLR196W 483 + TACGTTTACGATGACGGTGC Y|162|* silent|TAC>TAT|Y|162 PWP1 Periodic tryptophan (W) Protein 576.0 0 0 0 0 -1.2932750617260185 P21304 47.00898914055523 50.0 1.0 no 8806 chrXII_544484 24410 essential YLR196W 516 + AGCGATATTCCCGTTGAAGA S|173|R silent|AGC>AGT|S|173 PWP1 Periodic tryptophan (W) Protein 576.0 0 0 0 0 0.3878737266634291 P21304 0.9417110085487366 48.425917009576146 45.0 1.0 no 8807 chrXII_544493r 24411 essential YLR196W 528 - GCTTCATCACCTTCTTCAAC A|183|P A|183|T E|182|Q E|182|K PWP1 Periodic tryptophan (W) Protein 576.0 0 0 0 0 -0.05883359849862978 P21304 0.9573720097541808 0.9523990154266356 0.956179976463318 0.9475290179252625 50.43046640457072 45.0 1.0 no 8808 chrXII_544519r 24414 essential YLR196W 554 - CCAATCCACGAGCAACATCT L|191|F silent|TTG>TTA|L|191 G|190|A G|190|E PWP1 Periodic tryptophan (W) Protein 576.0 0 0 0 0 -0.4556427494209097 P21304 0.9587849974632264 0.9499930143356324 0.9438679814338684 49.456782071228076 50.0 1.0 no 8809 chrXII_544520r 24415 essential YLR196W 555 - ACCAATCCACGAGCAACATC L|191|F silent|TTG>TTA|L|191 V|192|L V|192|I PWP1 Periodic tryptophan (W) Protein 576.0 0 0 0 0 0.5179718180796823 P21304 0.9587849974632264 0.9539830088615416 0.9574310183525084 0.2690814137458801 0.3553242087364197 48.22464189128959 50.0 1.0 no 8810 chrXII_544550r 24416 essential YLR196W 585 - TCATGGTGAACGTAAAGTGC D|202|H D|202|N PWP1 Periodic tryptophan (W) Protein 576.0 0 0 0 0 -0.4799002202394913 P21304 0.9486550092697144 0.956179976463318 0.0 0.0 43.00689100190266 45.0 1.0 no 8811 chrXII_544567r 24417 essential YLR196W 602 - AAGCAGGCAACATTAAATCA A|207|P A|207|T PWP1 Periodic tryptophan (W) Protein 576.0 0 0 0 0 -1.1637088970503051 P21304 0.9573720097541808 0.9523990154266356 0.06890076398849487 0.5081875920295715 39.69135805283975 35.0 1.0 no 8812 chrXII_544693 24420 essential YLR196W 725 + GAACTTGGACTGTGTTGACA N|243|K silent|AAC>AAT|N|243 PWP1 Periodic tryptophan (W) Protein 576.0 0 0 0 0 0.1353089861779695 P21304 0.9439849853515624 0.15657000243663788 45.58086333996789 45.0 1.0 no 8813 chrXII_544715 24421 essential YLR196W 747 + GCCTTTCCCGATATGATTCT silent|GCC>GCG|A|250 silent|GCC>GCT|A|250 A|250|G A|250|V PWP1 Periodic tryptophan (W) Protein 576.0 0 0 0 0 0.2960280216063764 P21304 0.9484469890594482 0.9504740238189696 0.006841842085123062 1.0 53.5441135674809 45.0 1.0 no 8814 chrXII_544896r 24423 essential YLR196W 931 - GTTCAAATCCCATAGTTTTA L|316|F silent|TTG>TTA|L|316 PWP1 Periodic tryptophan (W) Protein 576.0 0 0 0 0 -0.16008916132738016 P21304 0.9587849974632264 0.0 43.49733473569575 30.0 1.0 no 8815 chrXII_544947r 24424 essential YLR196W 982 - AACATTTTTGTTTGAATGAA V|334|L V|334|I PWP1 Periodic tryptophan (W) Protein 576.0 0 0 0 0 0.32339708977331105 P21304 0.9539830088615416 0.9574310183525084 0.016710488125681874 0.08340168744325638 33.49159960752678 20.0 1.0 no 8816 chrXII_544976 24425 essential YLR196W 1008 + TCTGAATGGCACATGTTGAA S|337|C S|337|F PWP1 Periodic tryptophan (W) Protein 576.0 0 0 0 0 0.22887000820856626 P21304 0.945252001285553 0.9294660091400146 0.011283205822110176 0.031336378306150436 43.312570903887824 40.0 1.0 no 8817 chrXII_545013r 24426 essential YLR196W 1048 - TACTCGAGAATCATAACCAC V|356|L V|356|I R|355|P R|355|Q PWP1 Periodic tryptophan (W) Protein 576.0 0 0 0 0 -1.3954216461697957 P21304 0.9539830088615416 0.9574310183525084 0.9099509716033936 0.949662983417511 0.08301921933889389 0.055144798010587685 0.11787208169698715 0.19476766884326932 40.6556107953586 40.0 1.0 no 8818 chrXII_545200r 24427 essential YLR196W 1235 - TCAATGTCCAAACTGGTTTA L|418|F silent|TTG>TTA|L|418 PWP1 Periodic tryptophan (W) Protein 576.0 0 0 0 0 0.0016099379476384734 P21304 0.9587849974632264 0.010035162791609764 42.80808697971179 35.0 1.0 no 8819 chrXII_546355r 24433 essential YLR197W 261 - TTCTTTTTCGAGGAAGCCTT K|93|N silent|AAG>AAA|K|93 NOP56 NucleOlar Protein of 56.8 kDa 504.0 0 0 0 0 -0.3562178277581308 Q12460 0.06806141138076782 48.55017504335928 40.0 1.0 no 8820 chrXII_546693 24439 essential YLR197W 596 + TGGCTGGCATTTCCCCGAAC silent|GGC>GGG|G|200 silent|GGC>GGT|G|200 NOP56 NucleOlar Protein of 56.8 kDa 504.0 0 0 0 0 1.1593021852919851 Q12460 57.758928127919376 60.0 1.0 no 8821 chrXII_546705r 24440 essential YLR197W 611 - GTACCAATTTAGCCAGTTCG V|210|L V|210|I L|209|F silent|TTG>TTA|L|209 NOP56 NucleOlar Protein of 56.8 kDa 504.0 0 0 0 0 -1.488551801700822 Q12460 0.10472650080919266 0.13414376974105835 0.00895955041050911 49.097238056542274 45.0 1.0 no 8822 chrXII_546732 24442 essential YLR197W 635 + CAACTACACTTTTGCCAAGT N|213|K silent|AAC>AAT|N|213 Y|214|* silent|TAC>TAT|Y|214 NOP56 NucleOlar Protein of 56.8 kDa 504.0 0 0 0 0 0.08161038267965309 Q12460 0.06416777521371841 45.374133675704634 40.0 1.0 no 8823 chrXII_546861r 24445 essential YLR197W 767 - TATCTTGTCCCATGGAGATA D|262|H D|262|N NOP56 NucleOlar Protein of 56.8 kDa 504.0 0 0 0 0 -0.636913368808489 Q12460 0.0020803597290068865 0.006736996117979288 -0.4140000343322754 -0.23819999396800995 48.642107809409715 40.0 1.0 no 8824 chrXII_546869r 24446 essential YLR197W 775 - TTCTGATATATCTTGTCCCA E|265|Q E|265|K NOP56 NucleOlar Protein of 56.8 kDa 504.0 0 0 0 0 0.3081089205556668 Q12460 0.3824847340583801 0.4723236560821533 1.3188666105270386 0.6498000025749207 48.0714306806874 35.0 1.0 no 8825 chrXII_546997 24448 essential YLR197W 900 + CCAAACTTATCAGAATTGAT P|301|R P|301|L N|302|K silent|AAC>AAT|N|302 NOP56 NucleOlar Protein of 56.8 kDa 504.0 0 0 0 0 0.0611232472579431 Q12460 0.0 0.0 0.0069485679268836975 37.36214130702973 30.0 1.0 no 8826 chrXII_546997r 24449 essential YLR197W 903 - CCAATCAATTCTGATAAGTT G|308|R G|308|S L|306|F silent|TTG>TTA|L|306 NOP56 NucleOlar Protein of 56.8 kDa 504.0 0 0 0 0 -0.055746280942569344 Q12460 0.0 0.0 0.009372946806252004 38.88655999688967 30.0 1.0 no 8827 chrXII_547084 24450 essential YLR197W 987 + GCTTCAACGGTTCAAATTCT A|330|G A|330|V S|331|* S|331|L NOP56 NucleOlar Protein of 56.8 kDa 504.0 0 1 0 0 0.7413847233236791 Q12460 0.012658926658332348 0.003857173025608063 0.002427256666123867 44.890570759207385 40.0 1.0 no 8828 chrXII_547058r 24453 essential YLR197W 964 - TTGCTTAGATAAATTAGTTA K|327|N silent|AAG>AAA|K|327 NOP56 NucleOlar Protein of 56.8 kDa 504.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.2482951542027493 Q12460 0.004854440689086914 34.2184992602144 20.0 1.0 no 8829 chrXII_547173r 24455 essential YLR197W 1079 - CCTTAGAAATAAAACCACTG K|366|N silent|AAG>AAA|K|366 NOP56 NucleOlar Protein of 56.8 kDa 504.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.03579559580228449 Q12460 0.007451491430401801 36.75713599048788 35.0 1.0 no 8830 chrXII_547196r 24456 essential YLR197W 1102 - ACGACCCTTGTTCTTGGCAG R|374|P R|374|H G|373|A G|373|D NOP56 NucleOlar Protein of 56.8 kDa 504.0 0 1 0 0 -0.7033520849416051 Q12460 0.003077456029132009 0.003385126357898116 0.0 0.0 55.41017557066067 55.00000000000001 1.0 no 8831 chrXII_559591 24457 essential YLR208W 40 + ACGCTGTTCTAGACTATTAT A|15|G A|15|V D|14|E silent|GAC>GAT|D|14 SEC13 SECretory 297.0 0 0 0 0 0.9713132613103148 Q04491 0.8064339756965637 0.7841359972953796 0.8072220087051392 0.00290257902815938 0.18589898943901065 0.0 1.2660000324249268 -0.5206400156021118 0.4441399872303009 1.6419999599456787 0.5644000172615051 44.0730483053419 35.0 1.0 no 8832 chrXII_559619r 24458 essential YLR208W 71 - TGTCAGAAGAGCAGGTTGCA D|30|H D|30|N SEC13 SECretory 297.0 0 0 0 0 -1.5871013678160306 Q04491 0.9321119785308838 0.9500370025634766 0.0023655842524021864 0.04657155647873879 1.6759200096130369 0.448419988155365 50.67233409506935 50.0 1.0 no 8833 chrXII_559712 24461 essential YLR208W 161 + CCCAGTTTGGCGTGTTGATT P|55|R P|55|L P|55|A P|55|S SEC13 SECretory 297.0 0 0 0 0 -0.19221618131556287 Q04491 0.875944972038269 0.871084988117218 0.9043040275573729 0.8876969814300537 0.0015618819743394852 0.0021159532479941845 0.10131310671567917 0.009685777127742769 2.40858006477356 2.8252999782562256 2.334019899368286 2.930799961090088 55.34277721533687 50.0 1.0 no 8834 chrXII_559712r 24462 essential YLR208W 164 - CCCAATCAACACGCCAAACT W|61|S W|61|* W|61|C W|61|* SEC13 SECretory 297.0 0 0 0 0 -2.289402859540932 Q04491 0.7337859869003296 0.795274019241333 0.0 0.0 5.678959846496582 5.425340175628662 48.240723412907535 50.0 1.0 yes 8835 chrXII_559850 24464 essential YLR208W 299 + TTCTGTCAACTCTGTTCAAT S|101|C S|101|F silent|GTC>GTG|V|102 silent|GTC>GTT|V|102 SEC13 SECretory 297.0 0 0 0 0 0.3062728405294621 Q04491 0.7932569980621338 0.7643300294876099 0.0018099520821124317 0.0022187144495546818 1.7626199722290041 4.558499813079834 44.178593514754255 35.0 1.0 no 8836 chrXII_559988 24468 essential YLR208W 437 + TGGCGTTAACTCTGCTTCTT silent|GGC>GGG|G|147 silent|GGC>GGT|G|147 SEC13 SECretory 297.0 0 0 0 0 0.5061681561643551 Q04491 51.209281765183846 45.0 1.0 no 8837 chrXII_560056 24470 essential YLR208W 505 + AATCTCGCAAGTTTGTTACT S|170|C S|170|F R|171|G R|171|C SEC13 SECretory 297.0 0 1 0 0 0.011024526918209487 Q04491 0.7296389937400818 0.6992759704589844 0.7670130133628845 0.7469459772109985 0.054094769060611725 0.05454583466053009 0.05211871862411499 0.012686155736446379 0.29490000009536743 -0.6633999943733215 2.584460020065308 0.5328000187873839 43.751269187234755 35.0 1.0 no 8838 chrXII_560122r 24473 essential YLR208W 574 - GCTTTCCAGAACATAAGTTT S|198|T S|198|N E|197|Q E|197|K SEC13 SECretory 297.0 0 0 0 0 -2.3807580173464755 Q04491 0.8941439986228943 0.896107017993927 0.9180949926376344 0.8825470209121704 0.5562281608581543 0.4356098175048828 0.2305759787559509 0.3264161050319672 1.2170599699020386 0.3897199928760529 -0.08907999843358994 -0.3084999918937683 43.89141978203754 35.0 1.0 yes 8839 chrXII_565212r 24477 essential YLR212C 1047 + TCTGCGATGCACGTTAACAT S|350|C S|350|F A|351|G A|351|V 0 0 0 0 -0.9041991061635064 P53378 0.945252001285553 0.9294660091400146 0.9484469890594482 0.9504740238189696 0.009754277765750885 0.0044539221562445155 0.12374193221330645 0.017522379755973816 -0.2179999947547913 -0.692799985408783 0.5163999795913696 2.1370000839233403 47.04610719603448 45.0 0.0 no 8840 chrXII_565311r 24481 essential YLR212C 948 + AACGTTTATAATACAATCAT N|317|K silent|AAC>AAT|N|317 0 0 0 0 -0.16460006027077126 P53378 0.9439849853515624 0.004636753350496292 32.77025436667367 20.0 0.0 no 8841 chrXII_565241r 24482 essential YLR212C 1018 + AACGCATCAAATTCCCCTCA R|341|G R|341|C silent|CGC>CGG|R|341 silent|CGC>CGT|R|341 0 0 0 0 -0.0568241546077783 P53378 0.8994590044021606 0.8926740288734436 0.012457753531634808 0.0019711593631654978 49.840698873677475 45.0 0.0 no 8842 chrXII_565391 24483 essential YLR212C 871 - ATCTAACATGACGTCATAAC D|297|H D|297|N M|295|I M|295|I 0 0 0 0 -1.1869684869534756 P53378 0.9486550092697144 0.956179976463318 0.9553959965705872 0.9553959965705872 0.007942011579871178 0.015195640735328197 0.3101052939891815 0.3101052939891815 38.079428363637476 35.0 0.0 no 8843 chrXII_565473 24485 essential YLR212C 789 - GGGCTTAGGAAATGAAGTTC S|269|T S|269|N 0 0 0 0 -0.7070933546952873 P53378 0.9512869715690612 0.9536849856376648 0.2244775742292404 0.024722043424844745 43.330179304463854 45.0 0.0 no 8844 chrXII_565553r 24487 essential YLR212C 706 + CTTCAGTAACGAACAGTATA S|237|* S|237|L 0 0 0 0 -0.6501690018204083 P53378 0.9298099875450134 0.00316294259391725 38.84258765772671 35.0 0.0 no 8845 chrXII_565641r 24489 essential YLR212C 618 + GCTTCGTTGCTGAATATTTC A|207|G A|207|V S|208|W S|208|L 0 0 0 0 0.35531303612153986 P53378 0.9484469890594482 0.9504740238189696 0.9288619756698608 0.9298099875450134 0.4393472075462341 0.1808582991361618 0.00036391624598763883 0.002492656232789159 0.7275999784469604 1.8763999938964844 46.077010909191706 40.0 0.0 no 8846 chrXII_565714r 24490 essential YLR212C 545 + TCAATCTTATAACACTATTC Q|183|E Q|183|* S|184|C S|184|F 0 0 0 0 -0.0959155675085154 P53378 0.9590039849281312 0.945252001285553 0.9294660091400146 0.009714838117361069 0.0017563897417858245 0.0008570806821808219 35.101503864853036 25.0 0.0 no 8847 chrXII_565740 24491 essential YLR212C 522 - ACAACCTCAGAAGATCTTGC V|181|L V|181|I V|180|L V|180|I 0 0 0 0 -1.4402081560276174 P53378 0.9539830088615416 0.9574310183525084 0.9539830088615416 0.9574310183525084 0.00913051422685385 0.08237041532993318 0.008377107791602613 0.07316147536039352 0.012199999764561651 0.030400000512599945 -0.5717999935150146 -0.21559999883174896 45.58616001352226 45.0 0.0 no 8848 chrXII_565744r 24492 essential YLR212C 515 + GTTCCCTGCAAGATCTTCTG F|173|L silent|TTC>TTT|F|173 P|174|A P|174|S 0 0 0 0 0.06575938686617598 P53378 0.9387490153312684 0.9562489986419678 0.9498909711837769 0.1083253175020218 0.017380800098180767 0.08444415777921678 53.34436838089755 50.0 0.0 no 8849 chrXII_565801 24493 essential YLR212C 461 - GATCACACAGCGCTTCTAAG D|160|H D|160|N C|159|S C|159|Y 0 0 0 0 -2.6036627600460105 P53378 0.9486550092697144 0.956179976463318 0.9421560168266296 0.9290120005607604 0.0013566470006480813 0.003655718639492989 0.7387160062789917 0.024248482659459114 -0.24979999661445615 0.0430000014603138 47.69016942364674 50.0 0.0 yes 8850 chrXII_565805 24494 essential YLR212C 457 - ACACAGCGCTTCTAAGAGGT silent|CTG>CTC|L|158 silent|CTG>CTA|L|158 C|159|S C|159|Y 0 0 0 0 -0.0003497892556118265 P53378 0.9421560168266296 0.9290120005607604 0.7387160062789917 0.024248482659459114 -0.24979999661445615 0.0430000014603138 50.48190471335164 50.0 0.0 no 8851 chrXII_565741 24495 essential YLR212C 521 - CAACCTCAGAAGATCTTGCA V|180|L V|180|I E|179|D silent|GAG>GAA|E|179 0 0 0 0 -0.5289495937474396 P53378 0.9539830088615416 0.9574310183525084 0.94931298494339 0.008377107791602613 0.07316147536039352 1.0 -0.5717999935150146 -0.21559999883174896 46.416945946074684 45.0 0.0 no 8852 chrXII_565832 24497 essential YLR212C 430 - GAGCCCTGAACCGGTCCCTC silent|GGG>GGC|G|149 silent|GGG>GGA|G|149 G|149|A G|149|E 0 0 0 0 -6.592500900666064 P53378 0.9499930143356324 0.9438679814338684 0.0 0.0 63.91956064526778 70.0 0.0 yes 8853 chrXII_565848r 24499 essential YLR212C 411 + TTGCTGCACTCAGTAGCCGG L|139|V silent|CTG>TTG|L|139 H|140|D H|140|Y 0 0 0 0 -0.5851326901243064 P53378 0.9512209892272948 0.9473130106925964 0.9489949941635132 0.5881469249725342 0.0 0.0 1.2610000371932983 57.85807198364194 60.0 0.0 no 8854 chrXII_565396 24501 essential YLR212C 866 - ACATGACGTCATAACTGGAA M|295|I M|295|I V|294|L V|294|I 0 0 0 0 0.41455755567453934 P53378 0.9553959965705872 0.9553959965705872 0.9539830088615416 0.9574310183525084 0.3101052939891815 0.3101052939891815 0.06403011083602905 0.01625763811171055 41.18553890857481 40.0 0.0 no 8855 chrXII_565959r 24502 essential YLR212C 300 + GCTGGTAATTCTTGGGCCAA A|101|G A|101|V 0 0 0 0 1.6573606128340068 P53378 0.9484469890594482 0.9504740238189696 0.0 0.0 1.1260000467300415 2.722599983215332 52.849374732307005 50.0 0.0 no 8856 chrXII_566027r 24507 essential YLR212C 232 + ACGTGGAGAACACATTTCGT D|78|E silent|GAC>GAT|D|78 0 0 0 0 -0.7972819466697298 P53378 0.9532920122146606 0.8042702674865723 45.50588798339317 45.0 0.0 no 8857 chrXII_566135 24515 essential YLR212C 127 - GTCATCATCTCTTTCCGTAC D|49|H D|49|N D|48|H D|48|N 0 0 0 0 -2.544646960470168 P53378 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.0473160482943058 0.05417261272668839 0.0020395463798195124 0.006491602864116429 1.9076000452041624 0.2540000081062317 51.42862665111421 45.0 0.0 yes 8858 chrXII_566149r 24516 essential YLR212C 110 + TCAGCTTCCTGATTCCAGTA Q|38|E Q|38|* L|39|V L|39|F 0 0 0 0 -0.7814132526667188 P53378 0.9590039849281312 0.9512209892272948 0.9587849974632264 1.0 0.3744612634181976 0.09305133670568466 0.7197999954223633 2.164999961853028 5.435999870300293 54.18041550065488 45.0 0.0 no 8859 chrXII_566177r 24517 essential YLR212C 82 + AACACGCTATAGGCACCGAT H|29|D H|29|Y H|29|Q silent|CAC>CAT|H|29 0 0 0 0 -1.2837071435853191 P53378 0.9473130106925964 0.9489949941635132 0.9588389992713928 0.0 0.0 0.0 49.164314025661156 50.0 0.0 no 8860 chrXII_566216r 24519 essential YLR212C 43 + ACCACGTTGGTAAGTTTCTC H|16|D H|16|Y N|15|K silent|AAC>AAT|N|15 0 0 0 0 -0.5461976224832168 P53378 0.9473130106925964 0.9489949941635132 0.9439849853515624 0.05795625597238541 0.0070231566205620774 0.0 49.16602660784599 45.0 0.0 no 8861 chrXII_571104 24523 essential YLR215C 735 - TCAAGAACGAAACTTTTATC D|252|H D|252|N CDC123 Cell Division Cycle 360.0 0 0 0 0 -0.6287676073873519 Q05791 0.0 0.0 34.01218487714033 30.0 0.0 no 8862 chrXII_571113 24524 essential YLR215C 726 - AAACTTTTATCAGGAAACTT S|248|T S|248|N CDC123 Cell Division Cycle 360.0 0 0 0 0 -0.11961767343965653 Q05791 0.5491307377815247 0.8031232357025146 34.710837129435504 25.0 0.0 no 8863 chrXII_571157 24525 essential YLR215C 682 - TTCATCAATAAGGTCCTTGA E|234|Q E|234|K D|233|H D|233|N CDC123 Cell Division Cycle 360.0 0 0 0 0 0.26658682990722704 Q05791 0.5362033247947693 0.7144893407821655 0.0561029464006424 0.17908261716365814 43.56319895353686 35.0 0.0 no 8864 chrXII_571420r 24528 essential YLR215C 416 + TAACACTATGAAGTGTAACG N|140|K silent|AAC>AAT|N|140 T|141|S T|141|I CDC123 Cell Division Cycle 360.0 0 0 0 0 -0.8677310479530791 Q05791 0.18955956399440765 0.6816018223762512 0.029950270429253575 35.67896116745481 35.0 0.0 no 8865 chrXII_571425 24529 essential YLR215C 414 - TTACACTTCATAGTGTTATT C|144|S C|144|Y K|143|N silent|AAG>AAA|K|143 CDC123 Cell Division Cycle 360.0 0 0 0 0 -0.0014495107911932092 Q05791 0.0 0.0 0.02171044796705246 39.69017774462509 25.0 0.0 no 8866 chrXII_571562 24531 essential YLR215C 277 - CTCAACTTCTTGGACAAATT E|99|Q E|99|K V|98|L V|98|I CDC123 Cell Division Cycle 360.0 0 0 0 0 0.10233798347680699 Q05791 0.04188549891114235 0.04088226333260536 0.5972359776496887 0.5123623609542847 40.161686390991456 35.0 0.0 no 8867 chrXII_571568 24533 essential YLR215C 271 - TTCTTGGACAAATTCGGTGG E|97|Q E|97|K CDC123 Cell Division Cycle 360.0 0 0 0 0 0.8465492824459495 Q05791 0.5427104234695435 0.8852272033691406 44.65022158800548 45.0 0.0 no 8868 chrXII_571628 24534 essential YLR215C 211 - TTCATTTCTTATTATTTCCT E|77|Q E|77|K CDC123 Cell Division Cycle 360.0 0 1 0 0 0.036170590101893364 Q05791 0.12165266275405885 0.18830303847789764 41.507500341201755 20.0 0.0 no 8869 chrXII_571778r 24537 essential YLR215C 58 + AACACTGTTCTTACTCGTTT H|21|D H|21|Y H|21|Q silent|CAC>CAT|H|21 CDC123 Cell Division Cycle 360.0 0 0 0 0 -0.2239107523480061 Q05791 0.2407799065113068 0.07486167550086975 0.34517359733581543 44.54381416350458 35.0 0.0 no 8870 chrXII_574303 24540 no_effect YLR219W 152 + TTACTCAAGGTCGCACTCGC Y|52|* silent|TAC>TAT|Y|52 S|53|* S|53|L MSC3 Meiotic Sister-Chromatid recombination 728.0 0 1 0 0 -0.8180414910333356 Q05812 0.9298099875450134 0.17249299585819244 52.19751125263475 55.00000000000001 1.0 no 8871 chrXII_574337r 24541 no_effect YLR219W 189 - CTTCTTTGTCTCGGTATTGA R|69|T R|69|K MSC3 Meiotic Sister-Chromatid recombination 728.0 0 1 0 0 0.12907998099320128 Q05812 0.932735025882721 0.955805003643036 0.12301073968410492 0.4238938093185425 48.222981594987964 40.0 1.0 no 8872 chrXII_574493 24548 no_effect YLR219W 342 + CCGCCCGGTTATACTACTAA P|116|A P|116|S P|115|R P|115|L MSC3 Meiotic Sister-Chromatid recombination 728.0 0 1 0 0 -0.32082786476072744 Q05812 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.6155740022659302 0.6551137566566467 0.5163185000419617 0.33481866121292114 51.97481592852415 50.0 1.0 no 8873 chrXII_574493r 24549 no_effect YLR219W 345 - CCATTAGTAGTATAACCGGG G|122|R G|122|R MSC3 Meiotic Sister-Chromatid recombination 728.0 0 1 0 0 0.32618977405488625 Q05812 0.941340982913971 0.941340982913971 0.5186201333999634 0.5186201333999634 46.31255504754688 45.0 1.0 no 8874 chrXII_574631 24554 no_effect YLR219W 480 + ACACAAGTAACAGACCCTTC Q|162|E Q|162|* T|161|R T|161|I MSC3 Meiotic Sister-Chromatid recombination 728.0 0 1 0 0 0.2784184819136833 Q05812 0.9590039849281312 0.9476869702339172 0.9472420215606691 1.0 0.0 0.0 45.9192357418998 45.0 1.0 no 8875 chrXII_574717 24555 no_effect YLR219W 566 + CACGACTACGACTAAGAATT T|190|R T|190|M T|191|S T|191|I MSC3 Meiotic Sister-Chromatid recombination 728.0 0 0 0 0 -0.37945842189249424 Q05812 0.9476869702339172 0.9502379894256592 0.9491789937019348 0.9472420215606691 0.012919040396809578 0.014709556475281715 0.22238679230213165 0.03909555077552795 38.90915811518442 40.0 1.0 no 8876 chrXII_574727 24556 no_effect YLR219W 576 + ACTAAGAATTTGGTTCCATT T|193|S T|193|I MSC3 Meiotic Sister-Chromatid recombination 728.0 0 0 0 0 0.9393882736908348 Q05812 0.9491789937019348 0.9472420215606691 0.18187391757965088 0.3785791397094727 41.29914187418285 30.0 1.0 no 8877 chrXII_574831 24558 no_effect YLR219W 680 + TAACATTCACGATATAATCG N|228|K silent|AAC>AAT|N|228 MSC3 Meiotic Sister-Chromatid recombination 728.0 0 0 0 0 0.6721429307618078 Q05812 0.9439849853515624 0.5758576393127441 34.98904793262392 30.0 1.0 no 8878 chrXII_575091 24563 no_effect YLR219W 940 + AGCAAGCATCGACGACAAGA Q|315|E Q|315|* A|316|G A|316|V MSC3 Meiotic Sister-Chromatid recombination 728.0 0 0 0 0 -0.7576316213433573 Q05812 0.9590039849281312 0.9484469890594482 0.9504740238189696 1.0 0.38384148478508 0.3331644833087921 45.48712323335758 50.0 1.0 no 8879 chrXII_575162r 24566 no_effect YLR219W 1014 - TACATTTCTGCTTCGGTTAA M|344|I M|344|I MSC3 Meiotic Sister-Chromatid recombination 728.0 0 0 0 0 0.6521986954640729 Q05812 0.9553959965705872 0.9553959965705872 0.0 0.0 44.80390275454397 35.0 1.0 no 8880 chrXII_575169r 24567 no_effect YLR219W 1021 - CTTCAGATACATTTCTGCTT silent|CTG>CTC|L|346 silent|CTG>CTA|L|346 MSC3 Meiotic Sister-Chromatid recombination 728.0 0 0 0 0 0.5036413566260952 Q05812 45.151505629016754 35.0 1.0 no 8881 chrXII_575256r 24569 no_effect YLR219W 1108 - CCTGGATTTGTTACTCCCGA R|376|T R|376|K MSC3 Meiotic Sister-Chromatid recombination 728.0 0 0 0 0 0.8129736553524216 Q05812 0.932735025882721 0.955805003643036 0.10076551884412767 1.0 54.16768618116078 50.0 1.0 no 8882 chrXII_575257r 24570 no_effect YLR219W 1109 - TCCTGGATTTGTTACTCCCG R|376|T R|376|K R|376|S silent|AGG>AGA|R|376 MSC3 Meiotic Sister-Chromatid recombination 728.0 0 0 0 0 0.392333480093665 Q05812 0.932735025882721 0.955805003643036 0.9087679982185364 0.10076551884412767 1.0 0.09753783792257308 54.12328384241664 50.0 1.0 no 8883 chrXII_575311 24571 no_effect YLR219W 1160 + AAGCAGTAGTGATTCTCCGA S|388|R silent|AGC>AGT|S|388 MSC3 Meiotic Sister-Chromatid recombination 728.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.3327345817542871 Q05812 0.9417110085487366 0.2778339684009552 48.979772222935075 45.0 1.0 no 8884 chrXII_575344 24573 no_effect YLR219W 1193 + TCTTGTCAAATCTAATGTCG L|399|V L|399|F silent|GTC>GTG|V|400 silent|GTC>GTT|V|400 MSC3 Meiotic Sister-Chromatid recombination 728.0 0 0 0 0 0.8859850341181909 Q05812 0.9512209892272948 0.9587849974632264 0.6221505999565125 0.4757249653339386 39.58923434421701 35.0 1.0 no 8885 chrXII_575449 24574 no_effect YLR219W 1298 + TACACATTTTAAATCGAATA T|434|R T|434|I H|435|D H|435|Y MSC3 Meiotic Sister-Chromatid recombination 728.0 0 0 0 0 0.09004524633723178 Q05812 0.9476869702339172 0.9472420215606691 0.9473130106925964 0.9489949941635132 0.2625974118709564 0.22571399807929995 0.5584930181503296 0.2612329125404358 32.001731803315806 20.0 1.0 no 8886 chrXII_575558 24577 no_effect YLR219W 1407 + GCGAGGTATTACAACTCACA A|470|G A|470|V MSC3 Meiotic Sister-Chromatid recombination 728.0 0 1 0 0 -0.6053728651180319 Q05812 0.9484469890594482 0.9504740238189696 0.1088859960436821 0.08166324347257614 45.983765225555885 45.0 1.0 no 8887 chrXII_575672 24586 no_effect YLR219W 1521 + CCCAATGAGCAGCACTATTT silent|CCC>CCG|P|508 silent|CCC>CCT|P|508 P|508|R P|508|L MSC3 Meiotic Sister-Chromatid recombination 728.0 0 0 0 0 -0.2581170560012459 Q05812 0.9432820081710817 0.9430609941482544 0.6213122010231018 0.7937327027320862 49.970612915639784 45.0 1.0 no 8888 chrXII_575747 24590 no_effect YLR219W 1596 + TTGCAGAAGACAAAAACAAC Q|534|E Q|534|* MSC3 Meiotic Sister-Chromatid recombination 728.0 0 0 0 0 -1.0373964047196913 Q05812 0.9590039849281312 1.0 33.38539686959393 35.0 1.0 no 8889 chrXII_580157 24592 essential YLR222C 1595 - CATCCCATAGTCCACGCTTG D|538|H D|538|N W|537|C W|537|* UTP13 U Three Protein 817.0 0 0 0 0 0.06561171993708255 Q05946 0.9486550092697144 0.956179976463318 0.8858469724655151 0.0503392331302166 0.27072966098785395 0.0020700288005173206 55.645286641066825 55.00000000000001 0.0 no 8890 chrXII_580193 24598 essential YLR222C 1559 - CTTCCAATTCACCATTTTCT E|526|Q E|526|K L|525|F silent|TTG>TTA|L|525 UTP13 U Three Protein 817.0 0 0 0 0 0.0667367986491999 Q05946 0.956179976463318 0.9475290179252625 0.9587849974632264 0.5658305883407593 0.8048948049545288 0.1789393424987793 47.63491238403151 35.0 0.0 no 8891 chrXII_580209 24599 essential YLR222C 1543 - TTCTAGGTTCCAGATCTTAC E|521|Q E|521|K UTP13 U Three Protein 817.0 0 0 0 0 0.6492984316450916 Q05946 0.956179976463318 0.9475290179252625 0.2416897863149643 0.2728093564510345 47.61368627656623 40.0 0.0 no 8892 chrXII_580284 24601 essential YLR222C 1468 - AGCATTGATATCCTTTTCAT A|496|P A|496|T UTP13 U Three Protein 817.0 0 0 0 0 0.8028558407566141 Q05946 0.9573720097541808 0.9523990154266356 0.07059639692306519 0.3568316102027893 44.88110463253616 30.0 0.0 no 8893 chrXII_580295r 24602 essential YLR222C 1454 + TACTCGTCATGCCCATGAAA T|486|S T|486|I R|487|G R|487|C UTP13 U Three Protein 817.0 0 0 0 0 0.6124105034888246 Q05946 0.9491789937019348 0.9472420215606691 0.8994590044021606 0.8926740288734436 0.0 0.0 0.033386211842298515 0.006713613867759705 48.46445856763529 45.0 0.0 no 8894 chrXII_580345 24603 essential YLR222C 1407 - TCCATACTAGCAGTTGGCTT M|475|I M|475|I D|476|H D|476|N UTP13 U Three Protein 817.0 0 0 0 0 -0.1655826490722832 Q05946 0.9553959965705872 0.9553959965705872 0.9486550092697144 0.956179976463318 0.1853119134902954 0.1853119134902954 0.12170423567295074 0.5935205817222595 52.974460930679356 45.0 0.0 no 8895 chrXII_580346r 24604 essential YLR222C 1403 + TCCAAAGCCAACTGCTAGTA P|469|R P|469|L P|469|A P|469|S UTP13 U Three Protein 817.0 0 0 0 0 -0.1837823469310247 Q05946 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.300905704498291 0.0578574649989605 0.2775695323944092 0.12472787499427795 48.699234150043246 45.0 0.0 no 8896 chrXII_580443 24606 essential YLR222C 1309 - TGGCAATCCAACAGCAGTTA L|442|F silent|TTG>TTA|L|442 UTP13 U Three Protein 817.0 0 0 0 0 -2.08794523943447 Q05946 0.9587849974632264 0.016334664076566696 48.67510261574778 45.0 0.0 yes 8897 chrXII_580450r 24607 essential YLR222C 1299 + TCAGCTGCCGTAACTGCTGT S|434|* S|434|L A|435|G A|435|V UTP13 U Three Protein 817.0 0 0 0 0 -1.2464646510709547 Q05946 0.9298099875450134 0.9484469890594482 0.9504740238189696 0.07083679735660553 0.5741065740585327 0.19257649779319766 56.50214126497736 55.00000000000001 0.0 no 8898 chrXII_580573r 24610 essential YLR222C 1176 + TCATTGGATGCTACTGAGGA S|393|* S|393|L UTP13 U Three Protein 817.0 0 0 0 0 -0.02386324249295041 Q05946 0.9298099875450134 0.1482170671224594 47.51013678283761 45.0 0.0 no 8899 chrXII_580618 24612 essential YLR222C 1134 - TCATAAATTTCGACATCCAA E|385|Q E|385|K UTP13 U Three Protein 817.0 0 0 0 0 0.0676009694293667 Q05946 0.956179976463318 0.9475290179252625 0.3204755783081055 0.6665805578231812 38.798654908725716 30.0 0.0 no 8900 chrXII_580657r 24620 essential YLR222C 1092 + ATACCCGTCCCCGATTTATC P|366|A P|366|S P|366|R P|366|L UTP13 U Three Protein 817.0 0 0 0 0 0.05836495127317204 Q05946 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.24325335025787356 0.7308376431465149 0.15153010189533234 0.06633619219064713 55.36261065229911 50.0 0.0 no 8901 chrXII_580709 24621 essential YLR222C 1043 - AAGCTAATTTATTCAGCTCT A|354|P A|354|T UTP13 U Three Protein 817.0 0 1 0 0 1.0223196079081045 Q05946 0.9573720097541808 0.9523990154266356 0.0 0.0 41.932176971024326 30.0 0.0 no 8902 chrXII_580908 24624 essential YLR222C 844 - TAACTCTTCTATAGGTTTAT E|287|D silent|GAG>GAA|E|287 E|287|Q E|287|K UTP13 U Three Protein 817.0 0 0 0 0 0.7067900640163242 Q05946 0.94931298494339 0.956179976463318 0.9475290179252625 0.5612955093383789 0.2174549549818039 0.33032557368278503 38.771641068240115 25.0 0.0 no 8903 chrXII_581038 24627 essential YLR222C 714 - GACTCTACCTGTTGATTTAC E|244|D silent|GAG>GAA|E|244 E|244|Q E|244|K UTP13 U Three Protein 817.0 0 0 0 0 -0.7532775574990045 Q05946 0.94931298494339 0.956179976463318 0.9475290179252625 0.0 0.0 0.0 45.49449397275606 40.0 0.0 no 8904 chrXII_581102r 24628 essential YLR222C 647 + AGACGATATCATCAATCTCT D|217|E silent|GAC>GAT|D|217 UTP13 U Three Protein 817.0 0 0 0 0 1.1370128189723208 Q05946 0.9532920122146606 0.0 41.48701644909943 35.0 0.0 no 8905 chrXII_581131 24629 essential YLR222C 621 - CCGGAAAGTAAATTTAGGCT G|214|R G|214|S UTP13 U Three Protein 817.0 0 0 0 0 -0.7201705694525391 Q05946 0.941340982913971 0.951104998588562 0.005176909733563662 0.03452969342470169 42.008612730135326 40.0 0.0 no 8906 chrXII_581131r 24632 essential YLR222C 618 + CCAAGCCTAAATTTACTTTC P|207|R P|207|L S|208|R silent|AGC>AGT|S|208 UTP13 U Three Protein 817.0 0 0 0 0 0.07547800935937783 Q05946 0.9432820081710817 0.9430609941482544 0.9417110085487366 0.04990441352128983 0.03062527626752853 0.02067485637962818 42.50008722548153 35.0 0.0 no 8907 chrXII_581187r 24633 essential YLR222C 562 + AGCACACATCTGCTGTGAGA H|189|D H|189|Y H|189|Q silent|CAC>CAT|H|189 UTP13 U Three Protein 817.0 0 0 0 0 0.7366469349591375 Q05946 0.9473130106925964 0.9489949941635132 0.9588389992713928 0.0 0.0 0.0 51.36113204274909 50.0 0.0 no 8908 chrXII_581247 24634 essential YLR222C 505 - CCAAACCTTTACCATACCAT W|175|S W|175|* V|174|L V|174|I UTP13 U Three Protein 817.0 0 0 0 0 -0.2938108507857045 Q05946 0.8858469724655151 0.9539830088615416 0.9574310183525084 0.0 0.062378108501434326 0.5434496998786926 47.67126531836601 40.0 0.0 no 8909 chrXII_581347r 24637 essential YLR222C 402 + TACATTACTCATTCGTTCAA Y|135|* silent|TAC>TAT|Y|135 UTP13 U Three Protein 817.0 0 0 0 0 0.8819979812051975 Q05946 40.734374919667566 30.0 0.0 no 8910 chrXII_581409r 24639 essential YLR222C 340 + CAACGCTTCTCGCAGTCGGA T|115|R T|115|M L|116|V L|116|F UTP13 U Three Protein 817.0 0 0 0 0 0.1523969033743888 Q05946 0.9476869702339172 0.9502379894256592 0.9512209892272948 0.9587849974632264 0.008529189974069595 0.004541996400803328 0.0 0.0 54.24137387110841 60.0 0.0 no 8911 chrXII_581413r 24641 essential YLR222C 336 + ACTTCAACGCTTCTCGCAGT T|113|S T|113|I S|114|* S|114|L UTP13 U Three Protein 817.0 0 0 0 0 -1.0631054297768314 Q05946 0.9491789937019348 0.9472420215606691 0.9298099875450134 0.39165815711021423 0.007016134914010763 0.01761641353368759 52.442041822593524 50.0 0.0 no 8912 chrXII_581483 24644 essential YLR222C 269 - TGACAACTTTCCCGGTCTTA V|96|L V|96|I V|95|L V|95|I UTP13 U Three Protein 817.0 0 1 0 0 -0.3601433179350773 Q05946 0.9539830088615416 0.9574310183525084 0.9539830088615416 0.9574310183525084 0.4008334279060364 0.5492964386940002 1.0 0.9487130045890808 50.5717700849741 45.0 0.0 no 8913 chrXII_581539 24645 essential YLR222C 213 - TACGTGAGATATTGACCATC silent|ACG>ACC|T|77 silent|ACG>ACA|T|77 UTP13 U Three Protein 817.0 0 0 0 0 0.3501511445545393 Q05946 42.87031912028544 40.0 0.0 no 8914 chrXII_581554r 24646 essential YLR222C 195 + GCACTGAAATTAACTCCTGA L|67|V silent|CTG>TTG|L|67 A|66|G A|66|V UTP13 U Three Protein 817.0 0 0 0 0 -0.5924626056103304 Q05946 0.9512209892272948 0.9484469890594482 0.9504740238189696 0.12740401923656464 0.04242917150259018 0.21724818646907806 43.015604699776134 40.0 0.0 no 8915 chrXII_581629r 24649 essential YLR222C 120 + AACATAATCGATTTAACCCC N|41|K silent|AAC>AAT|N|41 UTP13 U Three Protein 817.0 0 0 0 0 0.5335622472638647 Q05946 0.9439849853515624 0.3559542298316956 41.652763743317045 35.0 0.0 no 8916 chrXII_581719r 24651 essential YLR222C 30 + TCGTTAAACCCTATTTATGC S|11|W S|11|L UTP13 U Three Protein 817.0 0 0 0 0 0.5541837576130313 Q05946 0.9288619756698608 0.9298099875450134 0.016771934926509857 0.24419015645980835 43.69539851284219 35.0 0.0 no 8917 chrXII_581711 24652 essential YLR222C 41 - CACTGCTTCCTGCATAAATA S|20|T S|20|N S|19|T S|19|N UTP13 U Three Protein 817.0 0 0 0 0 0.40435597502860976 Q05946 0.9512869715690612 0.9536849856376648 0.9512869715690612 0.9536849856376648 0.5979853272438049 0.4229156374931336 0.21404682099819186 0.04654523730278015 45.919941713853575 40.0 0.0 no 8918 chrXII_581736 24653 essential YLR222C 16 - TAACGATATACCTTTATATG silent|TCG>TCC|S|11 silent|TCG>TCA|S|11 UTP13 U Three Protein 817.0 0 0 0 0 0.6252780507130465 Q05946 35.157874509790474 25.0 0.0 no 8919 chrXII_582590 24655 essential YLR223C 2347 - TTTCCTTGTATTGCTGTCCA R|788|S silent|AGG>AGA|R|788 R|788|T R|788|K IFH1 Interacts with Fork Head 1085.0 0 0 0 0 -0.19757621848963736 P39520 53.47061805032831 40.0 0.0 no 8920 chrXII_582741r 24661 essential YLR223C 2193 + ATCAATGGCCATGAGATCAT I|732|M silent|ATC>ATT|I|732 IFH1 Interacts with Fork Head 1085.0 0 1 0 0 -1.3958629250005008 P39520 45.92227565024957 40.0 0.0 no 8921 chrXII_582917 24662 essential YLR223C 2020 - TTCATTACCAATATAGCCAA E|680|Q E|680|K IFH1 Interacts with Fork Head 1085.0 0 0 0 0 0.09279419210331694 P39520 41.96398579784119 30.0 0.0 no 8922 chrXII_582933r 24664 essential YLR223C 2001 + TCTAACAGAAAAGTTCCCAT S|668|C S|668|F N|669|K silent|AAC>AAT|N|669 IFH1 Interacts with Fork Head 1085.0 0 0 0 0 1.0033422260617706 P39520 41.454037416333854 35.0 0.0 no 8923 chrXII_583036 24665 essential YLR223C 1901 - CTTCATACCAATCTGCAGCA E|640|Q E|640|K IFH1 Interacts with Fork Head 1085.0 0 0 0 0 0.951522328657395 P39520 49.88185879008454 45.0 0.0 no 8924 chrXII_583097 24666 essential YLR223C 1840 - GTTCTCCATATCGTCTGTGT E|619|D silent|GAG>GAA|E|619 E|619|Q E|619|K IFH1 Interacts with Fork Head 1085.0 0 0 0 0 0.0784253880737511 P39520 53.78222856229394 45.0 0.0 no 8925 chrXII_583101 24667 essential YLR223C 1836 - TCCATATCGTCTGTGTGGGA M|618|I M|618|I E|619|Q E|619|K IFH1 Interacts with Fork Head 1085.0 0 0 0 0 -0.13229320526738736 P39520 53.758125633963964 50.0 0.0 no 8926 chrXII_583135r 24669 essential YLR223C 1799 + GCTGCTAAACATGAGTGAAT L|601|V silent|CTG>TTG|L|601 L|602|V silent|CTA>TTA|L|602 IFH1 Interacts with Fork Head 1085.0 0 0 0 0 -3.4359659511992806 P39520 41.8897916365159 40.0 0.0 yes 8927 chrXII_583197 24670 essential YLR223C 1740 - CTTCCCTCTCTTTTAACATC G|586|A G|586|E G|586|R G|586|R IFH1 Interacts with Fork Head 1085.0 0 0 0 0 0.6595223920830067 P39520 48.97694231221789 40.0 0.0 no 8928 chrXII_583243 24672 essential YLR223C 1694 - CGCGAAGCTGTTGATGTTCT R|571|P R|571|H IFH1 Interacts with Fork Head 1085.0 0 0 0 0 -0.8696174299668147 P39520 49.97115652478 50.0 0.0 no 8929 chrXII_583296r 24673 essential YLR223C 1638 + AAACCTTTTAGTATTATTGA P|548|A P|548|S P|548|R P|548|L IFH1 Interacts with Fork Head 1085.0 0 0 0 0 0.07331400229363419 P39520 35.88905510330903 20.0 0.0 no 8930 chrXII_583412r 24676 essential YLR223C 1522 + ACCTACCGCCCCCAAGTTCA L|509|V silent|CTA>TTA|L|509 N|508|K silent|AAC>AAT|N|508 IFH1 Interacts with Fork Head 1085.0 0 1 0 0 -0.17759579810039114 P39520 62.23782388758849 60.0 0.0 no 8931 chrXII_583557r 24677 essential YLR223C 1377 + TACTTTCATTACGACAGCGA Y|460|* silent|TAC>TAT|Y|460 H|462|D H|462|Y IFH1 Interacts with Fork Head 1085.0 0 0 0 0 0.20025632725080875 P39520 44.27772114335978 40.0 0.0 no 8932 chrXII_583717r 24680 essential YLR223C 1217 + AACGTCCCACGATGCTGACA T|407|R T|407|M S|408|C S|408|F IFH1 Interacts with Fork Head 1085.0 0 0 0 0 -0.408573814096437 P39520 52.338202941484674 55.00000000000001 0.0 no 8933 chrXII_583746 24681 essential YLR223C 1191 - TCACTGCATTCATCATCTGA S|403|T S|403|N E|404|Q E|404|K IFH1 Interacts with Fork Head 1085.0 0 0 0 0 -0.4165430716847053 P39520 47.75787266406263 40.0 0.0 no 8934 chrXII_583753 24682 essential YLR223C 1184 - ATTCATCATCTGAAGGCATA E|401|Q E|401|K D|400|H D|400|N IFH1 Interacts with Fork Head 1085.0 0 0 0 0 -0.2242922814026144 P39520 43.389437601980774 35.0 0.0 no 8935 chrXII_583754 24683 essential YLR223C 1183 - TTCATCATCTGAAGGCATAT E|401|Q E|401|K D|400|H D|400|N IFH1 Interacts with Fork Head 1085.0 0 0 0 0 -0.036179059738733435 P39520 43.389437601980774 35.0 0.0 no 8936 chrXII_583816 24685 essential YLR223C 1121 - AATCATATTTCCCGGAATTC D|380|H D|380|N IFH1 Interacts with Fork Head 1085.0 0 0 0 0 0.9414028254910152 P39520 43.27507059087088 35.0 0.0 no 8937 chrXII_583997 24688 essential YLR223C 940 - ATACTCATCATTGTCCACAT E|319|D silent|GAG>GAA|E|319 E|319|Q E|319|K IFH1 Interacts with Fork Head 1085.0 0 0 0 0 -0.21489336351239013 P39520 1.0 0.05487298592925072 0.04889397695660591 46.246326197871504 35.0 0.0 no 8938 chrXII_584000 24689 essential YLR223C 937 - CTCATCATTGTCCACATTGG E|319|Q E|319|K D|318|H D|318|N IFH1 Interacts with Fork Head 1085.0 0 0 0 0 0.3751522333414852 P39520 0.05487298592925072 0.04889397695660591 49.07591630556516 45.0 0.0 no 8939 chrXII_584011r 24690 essential YLR223C 923 + TACGAGAACAACCTCCAATG T|309|R T|309|M IFH1 Interacts with Fork Head 1085.0 0 0 0 0 -0.3650013671877501 P39520 42.54593156647468 45.0 0.0 no 8940 chrXII_584184r 24692 essential YLR223C 750 + AATCTTTATTATTATGGCGA L|252|V L|252|F IFH1 Interacts with Fork Head 1085.0 0 1 0 0 0.5949882616617682 P39520 38.53553386631626 25.0 0.0 no 8941 chrXII_584367r 24693 essential YLR223C 567 + GACGACGAACTCTCATTCGA D|190|E silent|GAC>GAT|D|190 D|191|E silent|GAC>GAT|D|191 IFH1 Interacts with Fork Head 1085.0 0 1 0 0 -0.11767935664180328 P39520 45.633247864970656 50.0 0.0 no 8942 chrXII_584500 24694 essential YLR223C 437 - TCACGTCAAAGTACGCATCC V|152|L V|152|M silent|GTG>GTC|V|152 silent|GTG>GTA|V|152 IFH1 Interacts with Fork Head 1085.0 0 0 0 0 0.539601415335935 P39520 48.26913290706784 50.0 0.0 no 8943 chrXII_584540 24695 essential YLR223C 397 - TTCATCTGACTCTGAAATAT E|139|Q E|139|K D|138|H D|138|N IFH1 Interacts with Fork Head 1085.0 0 0 0 0 0.371043283206886 P39520 0.10723156481981276 0.5530406832695007 38.46410099242888 30.0 0.0 no 8944 chrXII_584743r 24697 essential YLR223C 191 + AGGCACTACTACTACACAAC silent|GGC>GGG|G|65 silent|GGC>GGT|G|65 T|66|S T|66|I IFH1 Interacts with Fork Head 1085.0 0 0 0 0 0.4835625077203549 P39520 44.239261987493315 45.0 0.0 no 8945 chrXII_589423 24699 high_effect YLR226W 69 + TCACCACCACCAGCATCGAG P|25|A P|25|S S|24|* S|24|L BUR2 Bypass UAS Requirement 395.0 0 1 0 0 -0.2907825723574656 Q05949 0.9562489986419678 0.9498909711837769 0.9298099875450134 56.11319746157551 60.0 1.0 no 8946 chrXII_589432r 24700 high_effect YLR226W 81 - GCGTTAAACCCACTCGATGC A|34|P A|34|T BUR2 Bypass UAS Requirement 395.0 0 0 0 0 -0.1465488139490298 Q05949 0.9573720097541808 0.9523990154266356 0.8451643586158752 0.6204138994216919 51.329528818830106 55.00000000000001 1.0 no 8947 chrXII_589461r 24703 high_effect YLR226W 110 - TTTCTATCAAATCCGGCCAT E|43|Q E|43|K BUR2 Bypass UAS Requirement 395.0 0 0 0 0 -0.1710762833775969 Q05949 0.956179976463318 0.9475290179252625 0.2303522229194641 1.0 48.243021547869894 40.0 1.0 no 8948 chrXII_589620 24706 high_effect YLR226W 266 + TCTTTTTGATCACACCTATA L|90|V L|90|F BUR2 Bypass UAS Requirement 395.0 0 0 0 0 0.5112403353033617 Q05949 0.9512209892272948 0.9587849974632264 0.33570826053619385 0.1669747531414032 43.30272912695307 30.0 1.0 no 8949 chrXII_589643 24707 high_effect YLR226W 289 + CATCATGCATTCTATTTTAC S|98|* S|98|L BUR2 Bypass UAS Requirement 395.0 0 0 0 0 -0.13570135024184046 Q05949 0.9298099875450134 0.057924702763557434 40.83602076415536 30.0 1.0 no 8950 chrXII_589660 24708 high_effect YLR226W 306 + TACAGGTATTGGTTCATATA Y|103|* silent|TAC>TAT|Y|103 BUR2 Bypass UAS Requirement 395.0 0 0 0 0 -2.026731887784861 Q05949 41.28207681124411 30.0 1.0 yes 8951 chrXII_589687r 24709 high_effect YLR226W 336 - ATACATTCAGTTATGGCTGT C|118|S C|118|Y BUR2 Bypass UAS Requirement 395.0 0 0 0 0 0.9980792156579 Q05949 0.9421560168266296 0.9290120005607604 0.7254974246025085 1.0 45.727103711305396 35.0 1.0 no 8952 chrXII_589710 24710 high_effect YLR226W 356 + TCATATATCACAGGGAATTC H|120|D H|120|Y BUR2 Bypass UAS Requirement 395.0 0 0 0 0 0.008652609758289145 Q05949 0.9473130106925964 0.9489949941635132 0.6517390012741089 1.0 40.150920406489256 35.0 1.0 no 8953 chrXII_589736r 24711 high_effect YLR226W 385 - ATTCTCCATTGTTTTGCAAG E|134|D silent|GAG>GAA|E|134 E|134|Q E|134|K BUR2 Bypass UAS Requirement 395.0 0 0 0 0 0.4098599835887659 Q05949 0.94931298494339 0.956179976463318 0.9475290179252625 0.18256480991840365 0.028826339170336723 0.02278950251638889 45.50612480700744 35.0 1.0 no 8954 chrXII_589775r 24714 high_effect YLR226W 424 - CTCACAAGTCGCCTTAATAT E|148|Q E|148|K C|147|S C|147|Y BUR2 Bypass UAS Requirement 395.0 0 0 0 0 1.2171701749941979 Q05949 0.956179976463318 0.9475290179252625 0.9421560168266296 0.9290120005607604 0.30300289392471313 0.456301212310791 0.0335458442568779 0.005803534295409918 45.28611242667569 40.0 1.0 no 8955 chrXII_589933r 24715 high_effect YLR226W 582 - ACTTCTTCAATCAATTCTTT V|201|L V|201|M E|200|Q E|200|K BUR2 Bypass UAS Requirement 395.0 0 0 0 0 0.8123906388333344 Q05949 0.9539830088615416 0.9587630033493042 0.956179976463318 0.9475290179252625 0.5117614269256592 0.043652527034282684 0.1496903896331787 0.19975429773330688 39.80250935245897 25.0 1.0 no 8956 chrXII_590031 24716 high_effect YLR226W 677 + TCAAGAATCAAGAAATTTTA Q|227|E Q|227|* BUR2 Bypass UAS Requirement 395.0 0 0 0 0 1.3565221730286687 Q05949 0.9590039849281312 0.3442695736885071 30.109677148375567 20.0 1.0 no 8957 chrXII_590071 24718 high_effect YLR226W 717 + CCAGTTTCTTTATTGTGCGA P|240|R P|240|L BUR2 Bypass UAS Requirement 395.0 0 0 0 0 0.13025381119838342 Q05949 0.9432820081710817 0.9430609941482544 0.045178256928920746 0.02159859612584114 49.21408365374953 40.0 1.0 no 8958 chrXII_590193 24722 high_effect YLR226W 839 + ATTCCCTATCGAAGTAACGC F|281|L silent|TTC>TTT|F|281 P|282|A P|282|S BUR2 Bypass UAS Requirement 395.0 0 0 0 0 -0.1486143655960731 Q05949 0.9387490153312684 0.9562489986419678 0.9498909711837769 1.0 0.4649994671344757 0.5720087289810181 46.95598956285596 45.0 1.0 no 8959 chrXII_590237r 24723 high_effect YLR226W 886 - CTCTTCCAGTAACTTGTAAT E|302|Q E|302|K E|301|Q E|301|K BUR2 Bypass UAS Requirement 395.0 0 0 0 0 0.4950252305186248 Q05949 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.5963713526725769 0.9756799936294556 0.045782383531332016 0.03662052750587464 43.704573862352326 35.0 1.0 no 8960 chrXII_604338 24724 essential YLR229C 430 - TTTCAGTTCTCTTGCTAACC silent|CTG>CTC|L|149 silent|CTG>CTA|L|149 CDC42 Cell Division Cycle 191.0 0 0 0 0 0.16616585899069908 P19073 48.7028198345277 40.0 0.0 no 8961 chrXII_604363r 24726 essential YLR229C 402 + CGTCCGATTACATCAGAACA P|136|A P|136|S P|136|R P|136|L CDC42 Cell Division Cycle 191.0 0 0 0 0 -0.06750448548913493 P19073 0.07028929144144057 0.019641287624835968 0.017036965116858482 0.07164265960454941 45.442637009995174 45.0 0.0 no 8962 chrXII_604360 24727 essential YLR229C 408 - GAACCTTGTTCTGATGTAAT G|142|A G|142|D G|142|R G|142|S CDC42 Cell Division Cycle 191.0 0 0 0 0 -0.4966836627650648 P19073 0.29584801197052 0.0010975451441481712 0.0010472158901393414 0.007719449233263731 42.51306859261217 35.0 0.0 no 8963 chrXII_604428r 24728 essential YLR229C 337 + TCGGTACGCAGATTGATCTA silent|GTC>GTG|V|113 silent|GTC>GTT|V|113 T|115|R T|115|M CDC42 Cell Division Cycle 191.0 0 0 0 1 -0.9223228779102044 P19073 0.001334856613539159 0.0009027927881106734 47.38973685006352 45.0 0.0 no 8964 chrXII_604457 24731 essential YLR229C 311 - GGCATGGTACACCTGGACAA C|110|S C|110|Y CDC42 Cell Division Cycle 191.0 0 0 0 0 -1.5345755349018746 P19073 0.01578580215573311 0.10455647855997086 52.41961973834583 55.00000000000001 0.0 no 8965 chrXII_604503 24733 essential YLR229C 265 - TTCTTTAACGTTTTCAAAAG E|95|Q E|95|K CDC42 Cell Division Cycle 191.0 0 0 0 0 1.5089809754403862 P19073 0.17968757450580594 0.3420310914516449 -0.19950000941753387 -0.0988999605178833 34.16983340377789 25.0 0.0 no 8966 chrXII_604509 24735 essential YLR229C 259 - AACGTTTTCAAAAGAGGGTG V|93|L V|93|I CDC42 Cell Division Cycle 191.0 0 0 0 0 -0.2629105084323098 P19073 0.051435280591249466 0.3535774052143097 39.40493541467265 40.0 0.0 no 8967 chrXII_604549 24736 essential YLR229C 219 - ACCAAAAATACATCAGTAGA L|79|F silent|TTG>TTA|L|79 V|80|L V|80|I CDC42 Cell Division Cycle 191.0 0 0 0 0 0.7441828546613704 P19073 0.0381004773080349 0.5800377726554871 1.0 36.20643918613764 30.0 0.0 no 8968 chrXII_604618 24737 essential YLR229C 150 - TCAAACAAACCTAACGTATA D|57|H D|57|N L|55|F silent|TTG>TTA|L|55 CDC42 Cell Division Cycle 191.0 0 0 0 0 -1.0252789300845528 P19073 0.0006697025964967906 0.017913777381181717 0.0 7.795999526977539 0.8793000578880309 35.6811030908695 30.0 0.0 no 8969 chrXII_604664r 24738 essential YLR229C 101 + AACAGTGTTCGATAACTATG T|35|R T|35|I CDC42 Cell Division Cycle 191.0 0 0 0 0 -2.4204953196108643 P19073 0.0005963209550827743 0.01826954074203968 -0.6889600157737732 0.1329599916934967 38.08532882526913 35.0 0.0 yes 8970 chrXII_604712 24740 essential YLR229C 56 - TCGTTGTATAGGAGATTAGA silent|ACG>ACC|T|25 silent|ACG>ACA|T|25 CDC42 Cell Division Cycle 191.0 0 0 0 0 0.1388593312958488 P19073 41.398054023884015 35.0 0.0 no 8971 chrXII_623272r 24746 high_effect YLR242C 589 + TCATACTGAAAAAGTTGCAT F|197|L silent|TTC>TTT|F|197 L|199|V silent|CTG>TTG|L|199 0 0 0 0 -1.0461552241894647 Q06541 0.9387490153312684 0.9512209892272948 1.0 0.55680912733078 36.622870446610314 30.0 0.0 no 8972 chrXII_623280 24747 high_effect YLR242C 584 - ACTTTTTCAGTATGAAATAC K|201|N silent|AAG>AAA|K|201 0 0 0 0 1.0684403965782625 Q06541 0.9355990290641784 0.31193435192108154 34.843988042059486 25.0 0.0 no 8973 chrXII_623374r 24749 high_effect YLR242C 487 + TTACAAGTAAAGTGTTTACC T|164|R T|164|I 0 1 0 0 0.5310246522632679 Q06541 0.9476869702339172 0.9472420215606691 0.3538941442966461 0.4687897264957428 37.56284722605597 30.0 0.0 no 8974 chrXII_623645 24752 high_effect YLR242C 219 - TCATTTAGCGCTTTTCTTTT D|80|H D|80|N 0 0 0 0 0.4202105507390064 Q06541 0.9486550092697144 0.956179976463318 0.15232329070568085 0.6165058016777039 46.34560116508862 30.0 0.0 no 8975 chrXII_624322r 24760 essential YLR243W 122 - ACTTGGTAGCTTCTGCGGCA K|47|N silent|AAG>AAA|K|47 GPN3 Gly-Pro-Asn (N) motif 272.0 0 0 0 0 -0.6113614452283831 Q06543 0.9355990290641784 0.31055310368537903 0.9542000293731691 57.39675665435943 55.00000000000001 1.0 no 8976 chrXII_624378r 24762 essential YLR243W 178 - TTCTTCCATGACATCATCTA E|66|Q E|66|K E|65|Q E|65|K GPN3 Gly-Pro-Asn (N) motif 272.0 0 0 0 0 -0.6209338580839399 Q06543 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.029800688847899437 0.047816179692745216 0.12267374992370605 0.008300131186842918 46.25726760698905 35.0 1.0 no 8977 chrXII_624444 24763 essential YLR243W 241 + ATCTTTTGAAAAATCTAGAC L|82|V L|82|F GPN3 Gly-Pro-Asn (N) motif 272.0 0 0 0 0 0.4016441114491585 Q06543 0.9512209892272948 0.9587849974632264 0.015074226073920729 0.10933008044958116 0.9430000185966492 -0.5365999937057495 32.408103912913425 25.0 1.0 no 8978 chrXII_624598 24768 essential YLR243W 395 + CCTTTGCGCCACATATCTTT L|133|V L|133|F C|134|W silent|TGC>TGT|C|134 GPN3 Gly-Pro-Asn (N) motif 272.0 0 0 0 0 -0.33343357394255896 Q06543 0.9512209892272948 0.9587849974632264 0.9286419749259948 1.0 0.19616587460041046 0.0006290985038504003 8.456199645996094 53.25830060265025 45.0 1.0 no 8979 chrXII_624784 24772 essential YLR243W 581 + TGCAATGTTATTAATGGAAA A|195|G A|195|V GPN3 Gly-Pro-Asn (N) motif 272.0 0 0 0 0 -1.1425954237358116 Q06543 0.9484469890594482 0.9504740238189696 0.10918587446212767 1.0 0.4801999926567078 0.5586000084877014 34.455891719418624 25.0 1.0 no 8980 chrXII_625468 24774 high_effect YLR244C 844 - TACTACACTGCACTTATTTT V|288|L V|288|I V|287|L V|287|I MAP1 Methionine AminoPeptidase 387.0 0 0 0 0 -1.5245352902641736 Q01662 0.026592647656798363 0.09339633584022522 0.011011308059096336 0.06400013715028763 -0.18366000056266785 1.3452600240707395 1.958539962768555 0.16708000004291534 42.07751303387687 30.0 0.0 no 8981 chrXII_625517 24777 high_effect YLR244C 795 - AACTCTTGGAAGGTGGTACC E|271|D silent|GAG>GAA|E|271 E|271|Q E|271|K MAP1 Methionine AminoPeptidase 387.0 0 0 0 0 0.9959029414521724 Q01662 0.9049816727638244 0.04449540376663208 0.048085793852806084 48.79339158795676 50.0 0.0 no 8982 chrXII_625697 24779 high_effect YLR244C 615 - TCCTTCAAGACAGTTTTATC K|211|N silent|AAG>AAA|K|211 E|212|Q E|212|K MAP1 Methionine AminoPeptidase 387.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.9491035396316264 Q01662 0.03433074429631233 0.017052212730050087 0.05771367996931076 43.686843022937644 35.0 0.0 no 8983 chrXII_625729 24780 high_effect YLR244C 583 - ACAAATAACTTCATTGACAG C|201|S C|201|Y MAP1 Methionine AminoPeptidase 387.0 0 0 0 0 1.4293051072950334 Q01662 0.0 0.0 34.59655800530868 30.0 0.0 no 8984 chrXII_625802r 24782 high_effect YLR244C 507 + CACAATGAAACAATTAAGAG H|170|Q silent|CAC>CAT|H|170 MAP1 Methionine AminoPeptidase 387.0 0 0 0 0 -0.3696028925413475 Q01662 0.0061537991277873525 30.530651297524685 30.0 0.0 no 8985 chrXII_625803 24783 high_effect YLR244C 509 - CTCTCTTAATTGTTTCATTG R|176|T R|176|K K|175|N silent|AAG>AAA|K|175 MAP1 Methionine AminoPeptidase 387.0 0 1 0 0 -0.2163113479464016 Q01662 0.03022924065589905 0.1657067835330963 0.18099655210971832 40.462570651652356 30.0 0.0 no 8986 chrXII_625981 24786 high_effect YLR244C 331 - ACTGACTGGTAGCCCATTAG S|117|T S|117|N V|116|L V|116|I MAP1 Methionine AminoPeptidase 387.0 0 0 0 0 0.004333817795067418 Q01662 0.20365872979164126 0.10370387136936188 0.738023042678833 0.44905734062194813 0.18328000605106354 -0.2694999873638153 -0.6322000026702881 -0.5224000215530396 51.89174101097552 50.0 0.0 no 8987 chrXII_626010r 24788 high_effect YLR244C 299 + CCCTGAAGATATTCCTAAAC P|101|R P|101|L P|101|A P|101|S MAP1 Methionine AminoPeptidase 387.0 0 0 0 0 -1.0709167400449011 Q01662 0.004290981218218803 0.002594630466774106 0.006912733893841505 0.004492949228733778 43.0251387112628 40.0 0.0 no 8988 chrXII_626024 24789 high_effect YLR244C 288 - TCTTCAGGGACATACCTTCT D|103|H D|103|N E|102|Q E|102|K MAP1 Methionine AminoPeptidase 387.0 0 0 0 0 -0.4199103487031478 Q01662 0.5564165115356445 0.4818371534347534 0.39876070618629456 0.6736180782318115 51.36113204274921 45.0 0.0 no 8989 chrXII_626025 24790 high_effect YLR244C 287 - CTTCAGGGACATACCTTCTT E|102|Q E|102|K MAP1 Methionine AminoPeptidase 387.0 0 0 0 0 0.16207411382313008 Q01662 0.39876070618629456 0.6736180782318115 50.49585477460886 45.0 0.0 no 8990 chrXII_626072 24792 high_effect YLR244C 240 - TTACCAGAATATTTGAATTT G|86|A G|86|D G|86|R G|86|S MAP1 Methionine AminoPeptidase 387.0 0 1 0 0 0.5401182213771436 Q01662 0.0 0.0 0.0 0.0 34.9422832308058 20.0 0.0 no 8991 chrXII_626120r 24794 high_effect YLR244C 189 + GCTTTGCACAATGCTAAGGA A|64|G A|64|V H|66|D H|66|Y MAP1 Methionine AminoPeptidase 387.0 0 0 0 0 0.30931294967179296 Q01662 0.3842279016971588 0.302626371383667 0.00617305701598525 0.08091093599796295 47.40930712997465 45.0 0.0 no 8992 chrXII_626242 24798 high_effect YLR244C 70 - TTCTCTACCACATTGCAAAC E|30|Q E|30|K R|29|T R|29|K MAP1 Methionine AminoPeptidase 387.0 0 0 0 0 -0.0318494895753676 Q01662 0.5659632682800293 0.8870448470115662 0.03008783422410488 1.0 44.52567311887589 40.0 0.0 no 8993 chrXII_626292r 24799 high_effect YLR244C 17 + AACAGTTACTACCTCCGATC T|7|R T|7|I MAP1 Methionine AminoPeptidase 387.0 0 1 0 0 -0.11509379146460592 Q01662 47.74265703740024 45.0 0.0 no 8994 chrXII_636926 24801 essential YLR249W 146 + CTTCTTCGGTGAATTGGCCA F|50|L silent|TTC>TTT|F|50 F|51|L silent|TTC>TTT|F|51 0 0 0 0 -0.29721721770181664 P16521 1.0 0.7358113527297974 52.47773054442814 50.0 1.0 no 8995 chrXII_636927 24802 essential YLR249W 147 + TTCTTCGGTGAATTGGCCAA F|50|L silent|TTC>TTT|F|50 F|51|L silent|TTC>TTT|F|51 0 0 0 0 0.3810514693673101 P16521 1.0 0.7358113527297974 49.09444994299122 45.0 1.0 no 8996 chrXII_636943r 24803 essential YLR249W 166 - CTTCTTGTCCTTGATACCCT K|61|N silent|AAG>AAA|K|61 0 0 0 0 0.4165871379173349 P16521 0.05226990208029747 54.57466603895728 45.0 1.0 no 8997 chrXII_637023r 24805 essential YLR249W 246 - ACGATGTATGGTTCAACAGA V|89|L V|89|I 0 0 0 0 0.6355153896866441 P16521 0.4330754578113556 0.6490271091461182 43.07487286941574 40.0 1.0 no 8998 chrXII_637145r 24809 essential YLR249W 368 - ACAAAGCTTTGATGGCAACT L|129|F silent|TTG>TTA|L|129 A|128|P A|128|T 0 0 0 0 0.04280019923888781 P16521 0.020174631848931316 0.2475777566432953 0.4706417620182037 43.361865593979985 40.0 1.0 no 8999 chrXII_637208 24810 essential YLR249W 428 + GCAAGAAAAGATTGCTATTT Q|144|E Q|144|* 0 1 0 0 0.6434763988316083 P16521 0.058281101286411285 36.81588414477011 30.0 1.0 no 9000 chrXII_637273r 24811 essential YLR249W 496 - AATCAATTCTGGCATTCTTA L|171|F silent|TTG>TTA|L|171 0 1 0 0 -0.3155834788042435 P16521 0.03805188462138176 41.63624245312883 30.0 1.0 no 9001 chrXII_637284r 24812 essential YLR249W 507 - GACAAGACTGGAATCAATTC L|175|F silent|TTG>TTA|L|175 0 1 0 0 -1.885247072300471 P16521 0.047232892364263535 38.53063918811597 40.0 1.0 no 9002 chrXII_637298 24814 essential YLR249W 518 + AGTCTTGTCTGAAACCATGT silent|GTC>GTG|V|174 silent|GTC>GTT|V|174 0 0 0 0 0.6092698781796905 P16521 46.53073833998303 40.0 1.0 no 9003 chrXII_637363r 24818 essential YLR249W 586 - GTCAACAGTTTCGGTAGCCT D|202|H D|202|N V|201|L V|201|I 0 1 0 0 1.2690896460540446 P16521 0.10194773226976396 0.6887355446815491 0.1529180109500885 0.4319547712802887 53.70308806226535 50.0 1.0 no 9004 chrXII_637437r 24820 essential YLR249W 660 - ACGGTTTCTGGAACTTCAGT V|227|L V|227|I 0 0 0 0 1.3122297737360604 P16521 0.07618197053670883 1.0 48.744042169169006 45.0 1.0 no 9005 chrXII_637449 24821 essential YLR249W 669 + CCAGAAACCGTTCATTTGTT P|224|R P|224|L 0 0 0 0 -0.7338605907816722 P16521 0.061977948993444436 0.03903157636523247 46.38917414798135 40.0 1.0 no 9006 chrXII_637534r 24824 essential YLR249W 757 - TTCTCTTTCGTTCAAACCTC E|259|Q E|259|K R|258|T R|258|K 0 0 0 0 0.7319517910582419 P16521 0.593518853187561 0.9234645962715148 0.28779253363609314 0.6016975045204163 46.99880375255805 40.0 1.0 no 9007 chrXII_637523r 24825 essential YLR249W 746 - TCAAACCTCTGGACAACAAT L|255|F silent|TTG>TTA|L|255 G|254|A G|254|D 0 0 0 0 -0.3858513643014377 P16521 0.11361055076122285 0.5421733260154724 0.009253769181668758 41.741748246933405 40.0 1.0 no 9008 chrXII_637632r 24827 essential YLR249W 855 - GGCAACAATTTACCCAAGAA L|291|F silent|TTG>TTA|L|291 L|290|F silent|TTG>TTA|L|290 0 1 0 0 -0.4293000692579088 P16521 0.05462626367807388 0.016395339742302898 43.124055396888075 40.0 1.0 no 9009 chrXII_637696r 24830 essential YLR249W 919 - AGCTCTCAAAGTAACTTCTC A|313|P A|313|T R|312|T R|312|K 0 0 0 0 -0.7962264000789511 P16521 0.024797236546874046 0.10933179408311844 0.04741434380412102 0.5992178320884705 43.586199883177756 40.0 1.0 no 9010 chrXII_637764 24831 essential YLR249W 984 + ATTCCAGAAGTTTCTCACGC P|330|A P|330|S P|330|R P|330|L 0 0 0 0 -0.05665815592353862 P16521 0.733176589012146 0.7732756733894348 0.4916324317455292 0.277737021446228 48.98256705010357 45.0 1.0 no 9011 chrXII_637837r 24834 essential YLR249W 1060 - AATCTTAAATCTTGGAGCAA K|359|N silent|AAG>AAA|K|359 0 0 0 0 -0.33728622301546435 P16521 0.4532094299793243 37.658088639198354 30.0 1.0 no 9012 chrXII_637845r 24835 essential YLR249W 1068 - TCGACGACAATCTTAAATCT E|363|Q E|363|K V|362|L V|362|I 0 0 0 0 -0.5560071575311338 P16521 0.5713703632354736 0.852834165096283 1.0 0.5520764589309692 38.6581553898879 35.0 1.0 no 9013 chrXII_637955 24841 essential YLR249W 1175 + TATCTTCTTGCACGAAAAGA I|393|M silent|ATC>ATT|I|393 F|394|L silent|TTC>TTT|F|394 0 0 0 0 0.9622106570793304 P16521 0.22296206653118134 0.7081879377365112 39.65928136158658 35.0 1.0 no 9014 chrXII_638040 24844 essential YLR249W 1260 + TTCGACGACGAAGAAGACGA F|421|L silent|TTC>TTT|F|421 D|422|E silent|GAC>GAT|D|422 0 0 0 0 0.4397716381113021 P16521 0.21949660778045652 1.0 41.600552786414816 50.0 1.0 no 9015 chrXII_638034r 24845 essential YLR249W 1257 - TCTTCTTCGTCGTCGAAGTT D|426|H D|426|N E|425|Q E|425|K 0 0 0 0 0.4374924715384987 P16521 0.010673427954316141 0.02342628315091133 0.19338442385196689 0.20312859117984766 49.6800431922419 45.0 1.0 no 9016 chrXII_638126r 24848 essential YLR249W 1349 - TGGCTCTCTTCAATCTTAAT A|456|P A|456|T R|455|T R|455|K 0 0 0 0 0.4526831102115666 P16521 0.013581862673163414 0.009620231576263905 0.008735297247767448 0.2044302225112915 44.714299347681674 35.0 1.0 no 9017 chrXII_638232r 24849 essential YLR249W 1455 - GTTCTACATTCTTCTTGGGT R|491|T R|491|K C|490|S C|490|Y 0 0 0 0 0.9922250909875678 P16521 0.012038086540997028 0.4507225155830383 0.018861806020140648 0.0108849061653018 50.33719801768972 40.0 1.0 no 9018 chrXII_638236r 24850 essential YLR249W 1459 - GACGGTTCTACATTCTTCTT V|493|L V|493|I 0 0 0 0 -1.826160525837644 P16521 0.12762446701526642 0.3220635950565338 47.847317237190744 40.0 1.0 no 9019 chrXII_638237r 24851 essential YLR249W 1460 - AGACGGTTCTACATTCTTCT V|493|L V|493|I 0 0 0 0 0.20208573756082002 P16521 0.12762446701526642 0.3220635950565338 47.652539427482225 40.0 1.0 no 9020 chrXII_638285 24852 essential YLR249W 1505 + TCACTCTGACACTTCCGTCT H|503|Q silent|CAC>CAT|H|503 H|503|D H|503|Y 0 0 0 0 -1.2570482151966336 P16521 0.5019011497497559 0.6478023529052734 0.07010993361473082 53.754371985242024 50.0 1.0 no 9021 chrXII_638299r 24853 essential YLR249W 1522 - TTCGAAAACGAAATCCAAGA E|514|Q E|514|K 0 0 0 0 0.6234842094233888 P16521 0.4547797441482544 0.8689826130867004 35.91203628157251 35.0 1.0 no 9022 chrXII_638377r 24855 essential YLR249W 1600 - TGGCATAGCAATCATTTCAT M|539|I M|539|I 0 0 0 0 0.6177493464119738 P16521 0.19833089411258695 0.19833089411258695 44.631891790397454 35.0 1.0 no 9023 chrXII_638394 24856 essential YLR249W 1614 + ATGCCAATCTCTGCTTTGTC P|540|A P|540|S P|540|R P|540|L 0 0 0 0 0.5703695277894641 P16521 1.0 0.8272077441215515 0.22396066784858704 0.15516595542430878 51.93448362556318 45.0 1.0 no 9024 chrXII_638397 24857 essential YLR249W 1617 + CCAATCTCTGCTTTGTCTGG P|540|R P|540|L I|541|M silent|ATC>ATT|I|541 0 0 0 0 0.10588711044082567 P16521 0.22396066784858704 0.15516595542430878 0.009400236420333384 52.43777640213085 50.0 1.0 no 9025 chrXII_638790 24866 essential YLR249W 2010 + AACATGGAATTCCAATATCC N|671|K silent|AAC>AAT|N|671 0 1 0 0 -0.774755002582931 P16521 0.8687183856964111 40.988211274825396 35.0 1.0 no 9026 chrXII_638904 24870 essential YLR249W 2124 + ACTTTGATTAACGTCTTGAC T|709|S T|709|I 0 1 0 0 -0.451840111563168 P16521 0.0 0.0 40.36697161242222 35.0 1.0 no 9027 chrXII_639002 24872 essential YLR249W 2222 + TGCTCATATCGAATCTCATT A|742|G A|742|V H|743|D H|743|Y 0 1 0 0 0.3377078834313221 P16521 0.1077728345990181 0.09050115942955016 0.0 0.0 43.68072387072829 35.0 1.0 no 9028 chrXII_639059r 24873 essential YLR249W 2282 - TTTCTCTATCTTCACCGGTT E|767|Q E|767|K R|766|T R|766|K 0 1 0 0 -0.2264980780144161 P16521 0.0 0.0 0.07393830269575119 1.0 51.17120191578943 40.0 1.0 no 9029 chrXII_663707 24875 essential YLR259C 1276 - ACCTTCCTCAACTGCAGCTC G|432|R G|432|S G|432|A G|432|D HSP60 Heat Shock Protein 572.0 0 0 0 0 -5.224854655495636 P19882 0.0 0.0 0.0 0.0 57.03179103775591 55.00000000000001 0.0 yes 9030 chrXII_663712r 24876 essential YLR259C 1268 + CGCTACCAGAGCTGCAGTTG A|424|G A|424|V T|425|S T|425|I HSP60 Heat Shock Protein 572.0 0 0 0 0 -0.702470396085697 P19882 0.008195867761969566 0.002460210584104061 0.0 0.0 55.58985038194679 60.0 0.0 no 9031 chrXII_663814r 24878 essential YLR259C 1166 + GCGTTTGGCCAAATTGTCCG R|390|G R|390|C HSP60 Heat Shock Protein 572.0 0 1 0 0 -0.16509965771376572 P19882 0.0 0.0 53.304666570150566 55.00000000000001 0.0 no 9032 chrXII_663806 24879 essential YLR259C 1177 - AGCAACACCCCCGGACAATT A|399|P A|399|T V|398|L V|398|I HSP60 Heat Shock Protein 572.0 0 1 0 0 -4.527911909091976 P19882 0.0 0.0 0.006931057665497065 0.07115234434604645 54.163475145205155 55.00000000000001 0.0 yes 9033 chrXII_663922 24882 essential YLR259C 1061 - CCTTTGGACCACTACCGTTC K|360|N silent|AAG>AAA|K|360 HSP60 Heat Shock Protein 572.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.6757537825808733 P19882 0.048421122133731835 55.15753054538738 55.00000000000001 0.0 no 9034 chrXII_663930r 24884 essential YLR259C 1050 + ACCGTTATCCTGAACGGTAG silent|ACC>ACG|T|351 silent|ACC>ACT|T|351 T|351|S T|351|I HSP60 Heat Shock Protein 572.0 0 0 1 Series([], Name: modification, dtype: object) 0 -0.06766933081595315 P19882 0.04000776633620262 0.0018307495629414923 49.09599715678837 50.0 0.0 no 9035 chrXII_663958r 24885 essential YLR259C 1022 + TGACTCTATTACCGTTACTA D|342|E silent|GAC>GAT|D|342 S|343|C S|343|F HSP60 Heat Shock Protein 572.0 0 0 0 0 -0.1214851258580373 P19882 0.2887287139892578 0.0028023372869938608 0.004069326911121607 44.12089594309259 35.0 0.0 no 9036 chrXII_663980 24886 essential YLR259C 1003 - ACAAGAACCCAAGTTTTCTA C|341|S C|341|Y HSP60 Heat Shock Protein 572.0 0 0 0 0 -0.22209794297314114 P19882 0.011190232820808887 0.0023210581857711077 42.843499400301255 35.0 0.0 no 9037 chrXII_663988r 24887 essential YLR259C 992 + ACAATGTACCATAGAAAACT Q|332|E Q|332|* HSP60 Heat Shock Protein 572.0 0 0 0 0 0.8534741699173336 P19882 0.6849517226219177 36.26044407483039 30.0 0.0 no 9038 chrXII_664024r 24888 essential YLR259C 956 + TACTGTTTTTACTGAGGAGT T|320|S T|320|I HSP60 Heat Shock Protein 572.0 0 0 0 0 -0.04786516105387578 P19882 0.5465603470802307 0.19546236097812653 43.5985584736589 35.0 0.0 no 9039 chrXII_664083 24889 essential YLR259C 900 - TTTCTATTATCACCGAAACC R|306|T R|306|K HSP60 Heat Shock Protein 572.0 0 0 0 0 0.2758879056185599 P19882 0.005215230863541365 0.19591647386550906 42.16755564724241 35.0 0.0 no 9040 chrXII_664095r 24890 essential YLR259C 885 + GCTGTGAAGGCGCCTGGTTT A|296|G A|296|V HSP60 Heat Shock Protein 572.0 0 0 0 0 0.5754990278011345 P19882 0.012166325002908708 0.004058500751852989 58.93944027903899 60.0 0.0 no 9041 chrXII_664182 24891 essential YLR259C 801 - TCTTCAGCAATGATCAACAA D|274|H D|274|N E|273|Q E|273|K HSP60 Heat Shock Protein 572.0 0 0 0 0 -1.0508913318318551 P19882 0.0013189212186262012 0.004461909644305706 0.005340098403394222 0.0041237245313823214 40.4307519307427 35.0 0.0 no 9042 chrXII_664228r 24892 essential YLR259C 752 + TCAAGATATCTTGCCAGCTT Q|252|E Q|252|* HSP60 Heat Shock Protein 572.0 0 0 0 0 0.556338951113604 P19882 0.20427140593528748 48.455023605057995 40.0 0.0 no 9043 chrXII_664477r 24899 essential YLR259C 503 + AGCAACCATTTCTGCCAATG A|169|G A|169|V T|170|S T|170|I HSP60 Heat Shock Protein 572.0 0 0 0 0 -0.1432884032656465 P19882 0.2565401494503021 0.00414458941668272 0.05089407414197922 0.044279780238866806 48.679898338244705 45.0 0.0 no 9044 chrXII_664478r 24900 essential YLR259C 502 + TAGCAACCATTTCTGCCAAT A|169|G A|169|V T|170|S T|170|I HSP60 Heat Shock Protein 572.0 0 0 0 0 0.38623226584607656 P19882 0.2565401494503021 0.00414458941668272 0.05089407414197922 0.044279780238866806 48.182526137848704 40.0 0.0 no 9045 chrXII_664585r 24901 essential YLR259C 395 + TAACCCTATGGATTTGAGAA N|133|K silent|AAC>AAT|N|133 P|134|A P|134|S HSP60 Heat Shock Protein 572.0 0 0 0 0 0.4437167271945524 P19882 0.03942060470581055 0.22867313027381894 0.04848188161849976 41.81516111691246 35.0 0.0 no 9046 chrXII_664610 24902 essential YLR259C 373 - ACCAGCGGCGACATTTTTGA G|131|R G|131|S G|131|A G|131|D HSP60 Heat Shock Protein 572.0 0 0 0 0 1.0064670762590522 P19882 0.02771863155066967 0.026274735108017918 0.07974150776863098 0.0020948268938809638 51.719401041699655 50.0 0.0 no 9047 chrXII_664611r 24903 essential YLR259C 369 + TCCGTCAAAAATGTCGCCGC silent|TCC>TCG|S|124 silent|TCC>TCT|S|124 S|124|C S|124|F HSP60 Heat Shock Protein 572.0 0 0 0 0 -0.10464655557201236 P19882 0.0026145493611693387 0.0009987360099330542 50.227147902904555 55.00000000000001 0.0 no 9048 chrXII_664779 24909 essential YLR259C 204 - ACACCATCCTTAGTAATCTT G|74|A G|74|D V|75|L V|75|I HSP60 Heat Shock Protein 572.0 0 1 0 0 -1.8407928596138703 P19882 0.0049841306172311315 0.06442603468894957 0.010128065012395382 0.039822224527597434 46.522423321289246 35.0 0.0 no 9049 chrXII_664877 24912 essential YLR259C 106 - TTCGACACCCTTAAGAAGGG E|42|Q E|42|K V|41|L V|41|I HSP60 Heat Shock Protein 572.0 0 0 0 0 -3.808577981240415 P19882 0.09651526063680647 0.16286270320415494 0.01669045351445675 0.06277292966842651 47.19518050828378 50.0 0.0 yes 9050 chrXII_664961r 24913 essential YLR259C 19 + TTCGTAGTCGCGCTACTTTA R|8|G R|8|C HSP60 Heat Shock Protein 572.0 0 0 0 0 -0.2536204785853172 P19882 0.35738036036491394 0.17967775464057922 50.47417397153618 45.0 0.0 no 9051 chrXII_682846 24914 no_effect YLR271W 109 + CACTACGTTCAATCATGCCC L|38|V silent|CTA>TTA|L|38 R|39|G R|39|C CMG1 Cytoplasmic and Mitochondrial G-patch protein 1 274.0 0 0 0 0 1.1908692754469803 Q06152 0.10575544089078903 0.3896898925304413 0.07399541139602661 50.78295067278089 50.0 1.0 no 9052 chrXII_682794r 24915 no_effect YLR271W 60 - TCTCTTTTTGACTTCTTCTG R|26|T R|26|K D|27|H D|27|N CMG1 Cytoplasmic and Mitochondrial G-patch protein 1 274.0 0 0 0 0 -0.21801931319476006 Q06152 0.3644304871559143 1.0 0.1032302752137184 0.36574336886405945 45.56149098147216 35.0 1.0 no 9053 chrXII_682848 24916 no_effect YLR271W 111 + CTACGTTCAATCATGCCCAG R|39|G R|39|C CMG1 Cytoplasmic and Mitochondrial G-patch protein 1 274.0 0 0 0 0 0.7263870182624304 Q06152 0.3896898925304413 0.07399541139602661 50.43720253655749 50.0 1.0 no 9054 chrXII_682847 24917 no_effect YLR271W 110 + ACTACGTTCAATCATGCCCA L|38|V silent|CTA>TTA|L|38 R|39|G R|39|C CMG1 Cytoplasmic and Mitochondrial G-patch protein 1 274.0 0 0 0 0 0.31217427904081657 Q06152 0.10575544089078903 0.3896898925304413 0.07399541139602661 50.78295067278089 45.0 1.0 no 9055 chrXII_682934r 24919 no_effect YLR271W 200 - CTACCTTAATAGGCTCTTTT V|73|L V|73|I K|72|N silent|AAG>AAA|K|72 CMG1 Cytoplasmic and Mitochondrial G-patch protein 1 274.0 0 0 0 0 0.3742294095112472 Q06152 0.3112954199314117 0.4051181077957153 0.4604423344135285 45.765939523554614 35.0 1.0 no 9056 chrXII_683000r 24921 no_effect YLR271W 266 - GCATGTCATTCATTGTTGAT M|95|I M|95|I D|94|H D|94|N CMG1 Cytoplasmic and Mitochondrial G-patch protein 1 274.0 0 0 0 0 0.6152425515703182 Q06152 0.2803498208522797 0.2803498208522797 0.24392057955265045 0.8366032242774963 45.86657168500148 35.0 1.0 no 9057 chrXII_683102r 24922 no_effect YLR271W 368 - TCATTTCAAAAGCAACTTTT M|129|I M|129|I E|128|Q E|128|K CMG1 Cytoplasmic and Mitochondrial G-patch protein 1 274.0 0 0 0 0 -0.06240958397753865 Q06152 0.11107362061738968 0.11107362061738968 0.05229724571108818 0.052174627780914314 36.714358792063365 25.0 1.0 no 9058 chrXII_683307r 24927 no_effect YLR271W 573 - AACTTTTCACCTTTTATTGC K|197|N silent|AAG>AAA|K|197 CMG1 Cytoplasmic and Mitochondrial G-patch protein 1 274.0 0 0 0 0 0.9553961199729436 Q06152 0.7024273276329039 43.282719564075826 30.0 1.0 no 9059 chrXII_684564r 24930 essential YLR272C 2616 + ATCGAGGCAGAAACTCGGAA I|873|M silent|ATC>ATT|I|873 YCS4 Yeast Condensin Subunit 1176.0 0 0 0 0 -2.2493958528454283 Q06156 0.9598389863967896 0.2927279472351074 44.83450417294779 50.0 0.0 yes 9060 chrXII_684607r 24931 essential YLR272C 2573 + TGTCTATCTAGAGAAATGTG silent|GTC>GTG|V|859 silent|GTC>GTT|V|859 YCS4 Yeast Condensin Subunit 1176.0 0 0 0 0 -0.1481899796226094 Q06156 38.00802488064062 35.0 0.0 no 9061 chrXII_684902 24934 essential YLR272C 2281 - AAGCTCTTGATTTATTGCCT E|766|D silent|GAG>GAA|E|766 E|766|Q E|766|K YCS4 Yeast Condensin Subunit 1176.0 0 0 0 0 1.1450015284953732 Q06156 0.94931298494339 0.956179976463318 0.9475290179252625 0.20913603901863095 0.18847356736660004 0.6377695202827454 47.07061430186633 35.0 0.0 no 9062 chrXII_685011r 24937 essential YLR272C 2169 + TCACTTTTAAACATTGGACT L|725|V L|725|F S|724|* S|724|L YCS4 Yeast Condensin Subunit 1176.0 0 0 0 0 0.5891528183611979 Q06156 0.9512209892272948 0.9587849974632264 0.9298099875450134 0.0509440042078495 0.037978071719408035 0.7085075378417969 39.01247763344469 30.0 0.0 no 9063 chrXII_685121r 24938 essential YLR272C 2059 + ACAACCGTGACTCCGAAAAA N|687|K silent|AAC>AAT|N|687 N|688|K silent|AAC>AAT|N|688 YCS4 Yeast Condensin Subunit 1176.0 0 0 0 0 0.17943496081555838 Q06156 0.9439849853515624 0.9439849853515624 42.577212661808524 45.0 0.0 no 9064 chrXII_685122r 24939 essential YLR272C 2058 + AACAACCGTGACTCCGAAAA N|687|K silent|AAC>AAT|N|687 N|688|K silent|AAC>AAT|N|688 YCS4 Yeast Condensin Subunit 1176.0 0 0 0 0 0.5144975618578769 Q06156 0.9439849853515624 0.9439849853515624 42.577212661808524 45.0 0.0 no 9065 chrXII_685196r 24940 essential YLR272C 1984 + AACATGTCATTAATATCCTT H|663|D H|663|Y YCS4 Yeast Condensin Subunit 1176.0 0 0 0 0 0.5254152622736757 Q06156 0.9473130106925964 0.9489949941635132 0.4636124074459076 1.0 38.91349993955328 25.0 0.0 no 9066 chrXII_685195r 24941 essential YLR272C 1985 + ACATGTCATTAATATCCTTT H|663|D H|663|Y silent|GTC>GTG|V|664 silent|GTC>GTT|V|664 YCS4 Yeast Condensin Subunit 1176.0 0 0 0 0 0.09901525182195957 Q06156 0.9473130106925964 0.9489949941635132 0.4636124074459076 1.0 40.54925864652034 25.0 0.0 no 9067 chrXII_685295 24944 essential YLR272C 1888 - GCTTAGATTAATTAAATTTT S|636|T S|636|N YCS4 Yeast Condensin Subunit 1176.0 0 0 0 0 -0.2804931624218365 Q06156 0.9512869715690612 0.9536849856376648 1.0 0.007019794546067715 31.73229857330955 15.0 0.0 no 9068 chrXII_685335 24947 essential YLR272C 1848 - TCCTGCATATTGCAACTATC Q|622|H silent|CAG>CAA|Q|622 E|623|Q E|623|K YCS4 Yeast Condensin Subunit 1176.0 0 0 0 0 -0.4038979570965855 Q06156 0.9570760130882264 0.956179976463318 0.9475290179252625 0.1206444650888443 0.2931760549545288 0.027359355241060257 46.6659960479023 40.0 0.0 no 9069 chrXII_685429r 24949 essential YLR272C 1751 + GCTGCATTTGGTTTGGATGA L|585|V silent|CTG>TTG|L|585 H|586|D H|586|Y YCS4 Yeast Condensin Subunit 1176.0 0 0 0 0 -0.6496684186226931 Q06156 0.9512209892272948 0.9473130106925964 0.9489949941635132 0.011825436726212502 0.02380797080695629 0.017685983330011368 50.61574920752969 45.0 0.0 no 9070 chrXII_685464r 24950 essential YLR272C 1716 + GACATTGAGTTAAGCGAATT D|573|E silent|GAC>GAT|D|573 YCS4 Yeast Condensin Subunit 1176.0 0 0 0 0 1.5290953216840861 Q06156 0.9532920122146606 0.39022138714790333 39.53550614848285 35.0 0.0 no 9071 chrXII_685678r 24951 essential YLR272C 1502 + ACTTTCTAGAATAGAAAATG L|502|V L|502|F S|503|C S|503|F YCS4 Yeast Condensin Subunit 1176.0 0 1 0 0 0.7141823022296416 Q06156 0.9512209892272948 0.9587849974632264 0.945252001285553 0.9294660091400146 0.28541797399520874 0.06896062940359116 0.048638056963682175 0.045814942568540566 30.936581770627303 25.0 0.0 no 9072 chrXII_685583 24952 essential YLR272C 1600 - TATCTCTTTAATGAAACTAA E|539|D silent|GAG>GAA|E|539 E|539|Q E|539|K YCS4 Yeast Condensin Subunit 1176.0 0 0 0 0 -0.011048784917430287 Q06156 0.94931298494339 0.956179976463318 0.9475290179252625 0.0687577873468399 0.0920758843421936 0.12703001499176025 31.75497699867537 20.0 0.0 no 9073 chrXII_685870 24954 essential YLR272C 1313 - CCCATTCACTCAGCCTCAAT W|444|S W|444|* W|444|C W|444|* YCS4 Yeast Condensin Subunit 1176.0 0 0 0 0 -2.14983277880561 Q06156 0.8858469724655151 0.8858469724655151 0.0 0.0 55.20241768539569 50.0 0.0 yes 9074 chrXII_685870r 24955 essential YLR272C 1310 + CCAATTGAGGCTGAGTGAAT Q|438|E Q|438|* YCS4 Yeast Condensin Subunit 1176.0 0 0 0 0 -0.7765118543020076 Q06156 0.9590039849281312 0.061668470501899726 45.67673799785428 45.0 0.0 no 9075 chrXII_685883r 24958 essential YLR272C 1297 + CCATACATGGTAGCCAATTG silent|GCC>GCG|A|433 silent|GCC>GCT|A|433 H|435|D H|435|Y YCS4 Yeast Condensin Subunit 1176.0 0 0 0 0 0.3621849567784647 Q06156 0.9473130106925964 0.9489949941635132 0.01451155077666044 0.009379195049405098 47.410571112508144 45.0 0.0 no 9076 chrXII_685896r 24960 essential YLR272C 1284 + CATCCTTTTAAGGCCATACA P|430|A P|430|S P|430|R P|430|L YCS4 Yeast Condensin Subunit 1176.0 0 0 0 0 -0.03184709178743566 Q06156 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.04101260751485825 0.08416347950696945 0.009939721785485744 0.005894990637898445 48.24169411127758 40.0 0.0 no 9077 chrXII_685955r 24962 essential YLR272C 1225 + ACCGCTCCTCTTTAGTTCGT R|410|G R|410|C D|409|E silent|GAC>GAT|D|409 YCS4 Yeast Condensin Subunit 1176.0 0 1 0 0 -0.5777398730075973 Q06156 0.8994590044021606 0.8926740288734436 0.9532920122146606 0.007620520424097776 0.0010105184046551583 0.0 57.39085982229096 50.0 0.0 no 9078 chrXII_686067 24963 essential YLR272C 1116 - ATCGCCTTCGTTCTAACGTA silent|GCG>GCC|A|378 silent|GCG>GCA|A|378 A|378|P A|378|T YCS4 Yeast Condensin Subunit 1176.0 0 0 0 1 -0.7208962419535176 Q06156 0.9573720097541808 0.9523990154266356 0.02189398929476738 0.10223124921321868 50.09648288275418 45.0 0.0 no 9079 chrXII_686265 24967 essential YLR272C 918 - ATCTGTCGAAGCATTATTCC Q|312|H silent|CAG>CAA|Q|312 R|311|P R|311|Q YCS4 Yeast Condensin Subunit 1176.0 0 0 0 0 0.29471075302638805 Q06156 0.9570760130882264 0.9099509716033936 0.949662983417511 0.0 0.008899142034351826 0.02637450024485588 46.269520257272575 40.0 0.0 no 9080 chrXII_686360r 24968 essential YLR272C 820 + TCTTGAAAGAAATCAGCACC I|274|M silent|ATC>ATT|I|274 YCS4 Yeast Condensin Subunit 1176.0 0 0 0 0 0.5566874459376067 Q06156 0.9598389863967896 0.005978819914162159 40.547444874268926 40.0 0.0 no 9081 chrXII_686540r 24969 essential YLR272C 640 + CACTAAAGATGTTTATTCAA L|215|V silent|CTA>TTA|L|215 YCS4 Yeast Condensin Subunit 1176.0 0 0 0 0 0.5143048234207794 Q06156 0.9512209892272948 0.6925672292709351 34.349648747696556 25.0 0.0 no 9082 chrXII_686586 24970 essential YLR272C 597 - ATCTCTAATAACACAAATAA E|205|D silent|GAG>GAA|E|205 E|205|Q E|205|K YCS4 Yeast Condensin Subunit 1176.0 0 0 0 0 -0.5018370413288524 Q06156 0.94931298494339 0.956179976463318 0.9475290179252625 0.022695250809192657 0.07652123272418976 0.009169105440378187 30.44767736709588 20.0 0.0 no 9083 chrXII_686865 24972 essential YLR272C 318 - TCTAAATGCCTTTTCCACTG E|113|Q E|113|K YCS4 Yeast Condensin Subunit 1176.0 0 0 0 0 0.7337849123677873 Q06156 0.956179976463318 0.9475290179252625 0.06625230610370636 0.008994811214506626 46.83958039058234 40.0 0.0 no 9084 chrXII_687065 24975 essential YLR272C 118 - ATCTATTTGTTCGGGTGAAA D|46|H D|46|N YCS4 Yeast Condensin Subunit 1176.0 0 0 0 0 -0.5796564503084232 Q06156 0.9486550092697144 0.956179976463318 0.12411606311798094 0.5084631443023682 42.48307489569606 35.0 0.0 no 9085 chrXII_687057 24976 essential YLR272C 126 - GGACTAGCATCTATTTGTTC S|48|T S|48|N YCS4 Yeast Condensin Subunit 1176.0 0 0 0 0 0.881174145399068 Q06156 0.9512869715690612 0.9536849856376648 0.5441782474517822 0.7544038891792297 46.23762246016021 40.0 0.0 no 9086 chrXII_687103 24978 essential YLR272C 80 - TAACATTCAGTTCTCTGGAT V|33|L V|33|I YCS4 Yeast Condensin Subunit 1176.0 0 0 0 0 -2.659840747352852 Q06156 0.9539830088615416 0.9574310183525084 0.30492278933525085 0.17665699124336245 43.45485709431 35.0 0.0 yes 9087 chrXII_691579 24981 essential YLR274W 24 + TACAGTGCTCCTGTTTTACA Y|9|* silent|TAC>TAT|Y|9 MCM5 MiniChromosome Maintenance 775.0 0 0 0 0 -0.6497990095552877 P29496 49.95267638234583 40.0 1.0 no 9088 chrXII_691609r 24982 essential YLR274W 57 - TCAGTATTATCATCGTCGTT E|26|Q E|26|K MCM5 MiniChromosome Maintenance 775.0 0 0 0 0 0.04333062904145002 P29496 0.934378981590271 0.9223290085792542 0.5706059336662292 0.7243654727935791 45.319584881137025 35.0 1.0 no 9089 chrXII_691993r 24983 essential YLR274W 441 - TCAGAATCCAAATCTCTCAA E|154|Q E|154|K MCM5 MiniChromosome Maintenance 775.0 0 0 0 0 -0.5767794948939717 P29496 0.9840490221977234 0.972000002861023 0.6181849241256714 0.7398250699043274 40.88430679521736 35.0 1.0 no 9090 chrXII_692137 24988 essential YLR274W 582 + AACAATTTCAATTCTATCAC N|195|K silent|AAC>AAT|N|195 MCM5 MiniChromosome Maintenance 775.0 0 0 0 0 0.4080037172213491 P29496 0.965930998325348 0.9245805740356444 34.760097764371096 25.0 1.0 no 9091 chrXII_692249r 24991 essential YLR274W 697 - ATCAGGTCCACAATTTTTCT D|239|H D|239|N MCM5 MiniChromosome Maintenance 775.0 0 0 0 0 0.6139790711574482 P29496 0.9097489714622498 0.9209830164909364 0.0 0.0 46.798047637509505 35.0 1.0 no 9092 chrXII_692310 24992 essential YLR274W 755 + TCAACAGTTTTTAAAATTAC Q|253|E Q|253|* Q|254|E Q|254|* MCM5 MiniChromosome Maintenance 775.0 0 0 0 0 0.2879720171136054 P29496 0.9268540143966676 1.0024600028991701 0.2713271379470825 0.0 31.03984867589168 20.0 1.0 no 9093 chrXII_692338r 24993 essential YLR274W 786 - TCACCTACTGGAACCAGTTC G|268|A G|268|D E|269|Q E|269|K MCM5 MiniChromosome Maintenance 775.0 0 0 0 0 -0.6891593693687494 P29496 0.9901490211486816 0.9780880212783812 0.9315000176429749 0.9194509983062744 0.0 0.0 0.01031234860420227 0.00800430681556463 50.893643279586975 50.0 1.0 no 9094 chrXII_692350r 24994 essential YLR274W 798 - TTTCTAGGCATCTCACCTAC R|272|T R|272|K MCM5 MiniChromosome Maintenance 775.0 0 0 0 0 -0.33098839414985 P29496 0.979092001914978 0.9988390207290648 0.0 0.0 50.9054138260924 45.0 1.0 no 9095 chrXII_692391r 24995 essential YLR274W 839 - TAACTTTGTTTGTTAGGTAT V|286|L V|286|I MCM5 MiniChromosome Maintenance 775.0 0 0 0 0 0.4834726269869119 P29496 0.954316020011902 0.9619849920272828 0.10927676409482956 0.3899403214454651 39.307679432917276 25.0 1.0 no 9096 chrXII_692449 24997 essential YLR274W 894 + TCCATCTATAATTCTAAAAA silent|TCC>TCG|S|299 silent|TCC>TCT|S|299 S|299|C S|299|F MCM5 MiniChromosome Maintenance 775.0 0 0 0 0 0.09739122667558553 P29496 0.9077129960060121 0.8902170062065125 0.06168408691883087 0.0018626949749886987 32.98460547938623 20.0 1.0 no 9097 chrXII_692530r 25001 essential YLR274W 978 - ATACCTAATATTTTGATATA G|332|A G|332|D G|332|R G|332|S MCM5 MiniChromosome Maintenance 775.0 0 0 0 0 0.3246841050097734 P29496 0.9206920266151428 0.9102309942245485 0.904865026473999 0.9219319820404052 0.0 0.0 0.0 0.0 33.36652621685613 15.0 1.0 no 9098 chrXII_692643r 25004 essential YLR274W 1091 - TCAAAATTTCATAAAGCTTC L|370|F silent|TTG>TTA|L|370 MCM5 MiniChromosome Maintenance 775.0 0 0 0 0 0.05283001621658809 P29496 0.9641039967536926 0.44794869422912603 33.5661152465824 25.0 1.0 no 9099 chrXII_692644r 25005 essential YLR274W 1092 - GTCAAAATTTCATAAAGCTT L|370|F silent|TTG>TTA|L|370 MCM5 MiniChromosome Maintenance 775.0 0 0 0 0 -0.018110857774595937 P29496 0.9641039967536926 0.44794869422912603 34.998782011768014 25.0 1.0 no 9100 chrXII_692680r 25008 essential YLR274W 1128 - TCTTCATTACCAAAAATAGA D|383|H D|383|N E|382|Q E|382|K MCM5 MiniChromosome Maintenance 775.0 0 0 0 0 0.3337730649933637 P29496 0.9202659726142884 0.9315000176429749 0.9202449917793274 0.9081959724426271 0.0 0.0 0.5817478895187378 0.9000525474548341 35.241534495829285 25.0 1.0 no 9101 chrXII_692755r 25010 essential YLR274W 1203 - CCTCTTAACCTCATACCATC R|407|T R|407|K G|408|R G|408|S MCM5 MiniChromosome Maintenance 775.0 0 0 0 0 -1.5318049104155391 P29496 0.9788659811019896 0.9986129999160768 0.9727219939231871 0.9916149973869324 0.0 0.0 0.0 0.0 50.18427753561089 45.0 1.0 no 9102 chrXII_692756r 25011 essential YLR274W 1204 - ACCTCTTAACCTCATACCAT G|408|R G|408|S G|408|A G|408|D MCM5 MiniChromosome Maintenance 775.0 0 0 0 0 -0.3281331152307267 P29496 0.9727219939231871 0.9916149973869324 0.9903749823570251 0.9780880212783812 0.0 0.0 0.0 0.0 49.58044480746759 40.0 1.0 no 9103 chrXII_692813r 25012 essential YLR274W 1261 - TTTCAATAGTTGAGATTTGG L|426|F silent|TTG>TTA|L|426 MCM5 MiniChromosome Maintenance 775.0 0 1 0 0 -3.2471977008582886 P29496 1.002940058708191 0.0 37.989736308798115 30.0 1.0 yes 9104 chrXII_692854r 25013 essential YLR274W 1302 - CCAGATGTATATACCGCAAT G|441|R G|441|S MCM5 MiniChromosome Maintenance 775.0 0 0 0 0 -4.677178759593756 P29496 0.9727219939231871 0.991388976573944 0.0 0.0 45.392751879054906 40.0 1.0 yes 9105 chrXII_692929 25015 essential YLR274W 1374 + ACAAGAGAATTTTATTTGGA T|459|R T|459|I MCM5 MiniChromosome Maintenance 775.0 0 0 0 0 0.018564928537175462 P29496 0.9375799894332886 0.9496039748191832 0.00536440359428525 0.006103299092501403 35.07035979009788 25.0 1.0 no 9106 chrXII_692859 25016 essential YLR274W 1304 + TGCGGTATATACATCTGGTA A|436|G A|436|V MCM5 MiniChromosome Maintenance 775.0 0 0 0 0 0.20193167880701954 P29496 0.9747909903526306 0.9740179777145386 0.3279061317443848 0.013235543854534626 46.3109106799966 40.0 1.0 no 9107 chrXII_693096 25019 essential YLR274W 1541 + TTCTAGAACTAGTGTTTTAG S|515|C S|515|F MCM5 MiniChromosome Maintenance 775.0 0 0 0 0 0.2957572303691978 P29496 0.9077129960060121 0.8902170062065125 0.0029919305816292767 0.0013691723579540849 38.09530802449689 30.0 1.0 no 9108 chrXII_693265 25023 essential YLR274W 1710 + CACGTTATTAATATTCATAC H|571|Q silent|CAC>CAT|H|571 MCM5 MiniChromosome Maintenance 775.0 0 0 0 0 -0.190480100399917 P29496 1.0024800300598145 0.0 34.818273987112946 25.0 1.0 no 9109 chrXII_694563r 25026 essential YLR275W 59 - TCACCATAGCATCATTTATC V|26|L V|26|M silent|GTG>GTC|V|26 silent|GTG>GTA|V|26 SMD2 110.0 0 0 0 0 -0.7741368284217207 Q06217 44.84372169280698 35.0 1.0 no 9110 chrXII_694594r 25027 essential YLR275W 90 - TTTCTTAATGAGATTATCAC R|36|T R|36|K SMD2 110.0 0 0 0 0 -1.6536128773011876 Q06217 35.40928942022015 25.0 1.0 no 9111 chrXII_695550 25031 essential YLR276C 1261 - TACGAATGAAATTGCAGTAC V|427|L V|427|I DBP9 Dead Box Protein 594.0 0 0 0 0 0.6907313299555542 Q06218 0.02867010049521923 0.3336734175682068 36.5738809751403 35.0 0.0 no 9112 chrXII_695592 25032 essential YLR276C 1219 - TCTACCTACTCTATGCACGT R|413|T R|413|K G|412|A G|412|D DBP9 Dead Box Protein 594.0 0 0 0 0 -0.9356286960574758 Q06218 0.0 0.0 0.0 0.0 50.77386411514988 45.0 0.0 no 9113 chrXII_695690 25035 essential YLR276C 1121 - ATTCCTTATCTTTCTTCACT E|380|Q E|380|K K|379|N silent|AAG>AAA|K|379 DBP9 Dead Box Protein 594.0 0 0 0 0 -0.35347016369060563 Q06218 0.05763958767056465 0.011716512963175774 0.12715165317058566 46.957140927712366 30.0 0.0 no 9114 chrXII_695811 25036 essential YLR276C 1000 - ATCTTCCTCTTTTATGTACT D|340|H D|340|N E|339|Q E|339|K DBP9 Dead Box Protein 594.0 0 0 0 0 0.4916261775503394 Q06218 0.110315203666687 0.4474371075630188 0.5171817541122437 0.7246412634849548 46.32678852267036 30.0 0.0 no 9115 chrXII_695941r 25039 essential YLR276C 867 + AAGCTAGTTATGGAACAATT L|291|V silent|CTA>TTA|L|291 DBP9 Dead Box Protein 594.0 0 0 0 0 0.4142393369413664 Q06218 0.01040802337229252 37.73300990500843 30.0 0.0 no 9116 chrXII_696121 25040 essential YLR276C 690 - TCATTGAATTTAAGAATAGC D|237|H D|237|N DBP9 Dead Box Protein 594.0 0 1 0 0 -0.017586760588861827 Q06218 0.26231834292411804 0.07996293157339096 33.16045320426059 25.0 0.0 no 9117 chrXII_696167 25041 essential YLR276C 644 - AAGCCTGTATATCGTCATTT A|221|P A|221|T Q|220|H silent|CAG>CAA|Q|220 DBP9 Dead Box Protein 594.0 0 0 0 0 0.5348851012462811 Q06218 0.2425166815519333 0.6591313481330872 0.049290630966424935 46.04657317703641 35.0 0.0 no 9118 chrXII_696349 25042 essential YLR276C 462 - AACAAATCCAATAATTTACC L|160|F silent|TTG>TTA|L|160 DBP9 Dead Box Protein 594.0 0 1 0 0 -0.3217279582443616 Q06218 0.6915125846862793 34.6455405099548 25.0 0.0 no 9119 chrXII_696376r 25043 essential YLR276C 432 + GATCAACCAGAAATCATAGT Q|146|E Q|146|* P|147|A P|147|S DBP9 Dead Box Protein 594.0 0 0 0 0 0.19187925256252225 Q06218 0.5696799755096436 0.0 0.0 39.54835473427357 35.0 0.0 no 9120 chrXII_696680r 25048 essential YLR276C 128 + TCAATCACATGCTATTCCTT Q|44|E Q|44|* S|45|* S|45|L DBP9 Dead Box Protein 594.0 0 0 0 0 -0.6435439186838078 Q06218 0.0 0.1068476140499115 46.134886390386384 35.0 0.0 no 9121 chrXII_696664 25049 essential YLR276C 147 - CTCTTCTGTTGTAAAGCCAA K|55|N silent|AAG>AAA|K|55 Q|54|H silent|CAG>CAA|Q|54 DBP9 Dead Box Protein 594.0 0 0 0 0 0.06682447012998949 Q06218 0.2113228142261505 0.06042264774441719 45.9583580300876 40.0 0.0 no 9122 chrXII_697800 25050 essential YLR277C 1676 - TCGTTGTAGAAAGATCGGGA silent|ACG>ACC|T|565 silent|ACG>ACA|T|565 YSH1 Yeast Seventy-three Homolog 779.0 0 0 0 0 -0.2281175094917323 Q06224 43.92959251937368 45.0 0.0 no 9123 chrXII_697764 25051 essential YLR277C 1712 - TACAATTTACACGAACTGAC C|577|S C|577|Y YSH1 Yeast Seventy-three Homolog 779.0 0 0 0 0 -0.3620388232953088 Q06224 0.9421560168266296 0.9290120005607604 0.2629394829273224 0.009618707932531834 36.645667059416674 35.0 0.0 no 9124 chrXII_697889r 25053 essential YLR277C 1584 + CACAAAGACATAGTCGTTTC H|529|Q silent|CAC>CAT|H|529 YSH1 Yeast Seventy-three Homolog 779.0 0 0 0 0 0.5658237998984372 Q06224 0.9588389992713928 0.5735195875167847 40.599340404076536 40.0 0.0 no 9125 chrXII_698090 25057 essential YLR277C 1386 - TCTACTTCAACACAGTTTCT D|469|H D|469|N V|468|L V|468|I YSH1 Yeast Seventy-three Homolog 779.0 0 0 0 0 0.012450597259610148 Q06224 0.9486550092697144 0.956179976463318 0.9539830088615416 0.9574310183525084 0.1547677367925644 0.4542685747146606 0.759222149848938 0.1630065143108368 -0.8253999948501587 -1.055400013923645 44.1846947023343 35.0 0.0 no 9126 chrXII_698141r 25058 essential YLR277C 1332 + TCCAATTTCGCGTCTTTAAA silent|TCC>TCG|S|445 silent|TCC>TCT|S|445 S|445|C S|445|F YSH1 Yeast Seventy-three Homolog 779.0 0 0 0 0 0.024816378628761068 Q06224 0.945252001285553 0.9294660091400146 0.025440631434321404 0.02216184139251709 43.77930727668684 35.0 0.0 no 9127 chrXII_698187r 25062 essential YLR277C 1286 + TCATGGAGAAGCCAATCCCA H|430|D H|430|Y YSH1 Yeast Seventy-three Homolog 779.0 1 Series([], Name: modification, dtype: object) 0 0 0 -1.6967928435475277 Q06224 0.9473130106925964 0.9489949941635132 0.0 0.0 51.74093311764216 50.0 0.0 no 9128 chrXII_698204 25063 essential YLR277C 1272 - CCATGAACAAGGATGATATT G|431|R G|431|R YSH1 Yeast Seventy-three Homolog 779.0 0 1 0 0 -4.3601958299285135 Q06224 0.941340982913971 0.941340982913971 0.0 0.0 39.278986626160815 35.0 0.0 yes 9129 chrXII_698204r 25064 essential YLR277C 1269 + CCAAATATCATCCTTGTTCA P|424|R P|424|L YSH1 Yeast Seventy-three Homolog 779.0 0 0 0 0 0.4788235139036942 Q06224 0.9432820081710817 0.9430609941482544 0.2783122360706329 0.10969347506761552 45.03766022237193 35.0 0.0 no 9130 chrXII_698291 25065 essential YLR277C 1185 - TCTTCAACTTGACAACGTCT E|402|Q E|402|K E|401|Q E|401|K YSH1 Yeast Seventy-three Homolog 779.0 0 0 0 0 -0.1402890134686588 Q06224 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.20834070444107056 0.2299329936504364 0.24846595525741574 0.3408684432506561 -0.0926000028848648 -0.9805999994277954 -0.6977999806404114 -0.972000002861023 44.047300061656706 40.0 0.0 no 9131 chrXII_698371 25067 essential YLR277C 1105 - TTTCGCCATTGTTCCTTCGA silent|GCG>GCC|A|374 silent|GCG>GCA|A|374 A|374|P A|374|T YSH1 Yeast Seventy-three Homolog 779.0 0 0 0 0 0.3460732450030451 Q06224 0.9573720097541808 0.9523990154266356 0.007854911498725414 0.005532453767955303 7.816999912261963 3.23799991607666 53.87307714142702 45.0 0.0 no 9132 chrXII_698520r 25071 essential YLR277C 953 + ATCTTATCTTAGAAACTTGG S|319|C S|319|F YSH1 Yeast Seventy-three Homolog 779.0 0 0 0 0 0.42770772905595017 Q06224 0.945252001285553 0.9294660091400146 0.022635571658611298 0.03283284977078438 37.32860345649664 30.0 0.0 no 9133 chrXII_698599 25072 essential YLR277C 877 - ATCATTCATCATATTTACAT D|299|H D|299|N M|297|I M|297|I YSH1 Yeast Seventy-three Homolog 779.0 0 0 0 0 -0.4122728963907653 Q06224 0.9486550092697144 0.956179976463318 0.9553959965705872 0.9553959965705872 0.02336178161203861 0.07736971974372864 0.008777805604040623 0.008777805604040623 -0.17180000245571134 0.03339999914169312 -0.4169999957084656 -0.4169999957084656 37.28996616170895 20.0 0.0 no 9134 chrXII_698684r 25073 essential YLR277C 789 + CAACATGCTGATGAACTCGG H|265|D H|265|Y YSH1 Yeast Seventy-three Homolog 779.0 0 0 0 0 -4.137037770757764 Q06224 0.9473130106925964 0.9489949941635132 0.020773217082023617 0.03882826119661331 44.04385807087625 50.0 0.0 yes 9135 chrXII_698687r 25076 essential YLR277C 786 + TCTCAACATGCTGATGAACT Q|264|E Q|264|* S|263|C S|263|F YSH1 Yeast Seventy-three Homolog 779.0 0 0 0 0 0.3429814147502032 Q06224 0.9590039849281312 0.945252001285553 0.9294660091400146 0.7446640729904175 0.025688724592328068 0.02431920543313026 43.203111188444154 40.0 0.0 no 9136 chrXII_698710r 25077 essential YLR277C 763 + TGCTTATACTGGATGAGTAC L|256|V L|256|F YSH1 Yeast Seventy-three Homolog 779.0 0 0 0 0 0.1182669885500788 Q06224 0.9512209892272948 0.9587849974632264 0.0 0.0 0.8065999746322632 -0.3529999852180481 43.33905959529659 40.0 0.0 no 9137 chrXII_698750r 25078 essential YLR277C 723 + CTACTGCCTGTTTTTGCTTT L|243|V silent|CTG>TTG|L|243 P|244|A P|244|S YSH1 Yeast Seventy-three Homolog 779.0 0 0 0 0 -0.21003725352877967 Q06224 0.9512209892272948 0.9562489986419678 0.9498909711837769 0.033581532537937164 0.0 0.0 51.91350298148393 40.0 0.0 no 9138 chrXII_698776 25079 essential YLR277C 700 - ACGGCCTCCTCTCATCACTG R|240|P R|240|H G|239|A G|239|D YSH1 Yeast Seventy-three Homolog 779.0 0 0 0 0 -0.7655326577626941 Q06224 0.9099509716033936 0.9570810198783876 0.9499930143356324 0.9446240067481996 0.003249200526624918 0.036557186394929886 0.0 0.0 58.87361941507595 60.0 0.0 no 9139 chrXII_698749r 25080 essential YLR277C 724 + TACTGCCTGTTTTTGCTTTA L|243|V silent|CTG>TTG|L|243 P|244|A P|244|S YSH1 Yeast Seventy-three Homolog 779.0 0 0 0 0 0.7176607532226664 Q06224 0.9512209892272948 0.9562489986419678 0.9498909711837769 0.033581532537937164 0.0 0.0 49.447404865895 35.0 0.0 no 9140 chrXII_698817 25082 essential YLR277C 659 - GCTTCCTTTCTCTATTTAAA K|226|N silent|AAG>AAA|K|226 R|225|S silent|AGG>AGA|R|225 YSH1 Yeast Seventy-three Homolog 779.0 0 0 0 0 0.22091350166939566 Q06224 0.9355990290641784 0.9087679982185364 0.032833702862262726 0.7278732657432556 44.08701393412207 30.0 0.0 no 9141 chrXII_698818 25083 essential YLR277C 658 - CTTCCTTTCTCTATTTAAAC R|225|S silent|AGG>AGA|R|225 R|225|T R|225|K YSH1 Yeast Seventy-three Homolog 779.0 0 0 0 0 0.2241897073889508 Q06224 0.9087679982185364 0.932735025882721 0.955805003643036 0.7278732657432556 0.5327879786491394 0.9599776268005372 40.84229419458126 30.0 0.0 no 9142 chrXII_698871r 25085 essential YLR277C 602 + TTCATCCAACGTATTAATTG S|202|* S|202|L S|203|C S|203|F YSH1 Yeast Seventy-three Homolog 779.0 0 0 0 0 -0.900926343311898 Q06224 0.9298099875450134 0.945252001285553 0.9294660091400146 0.021931558847427368 0.029158301651477814 0.01860598847270012 -1.000599980354309 38.83842361025319 30.0 0.0 no 9143 chrXII_698904r 25086 essential YLR277C 569 + TCGTCACTTAAATTCTGCTG R|191|G R|191|C H|192|D H|192|Y YSH1 Yeast Seventy-three Homolog 779.0 0 0 0 0 0.15540337938033788 Q06224 0.8994590044021606 0.8926740288734436 0.9473130106925964 0.9489949941635132 0.00452201534062624 0.0009029357461258768 0.0 0.0 -18.971599578857425 -10.407400131225586 -2.625600099563598 2.0397999286651607 43.721153448531815 40.0 0.0 no 9144 chrXII_699000r 25087 essential YLR277C 473 + ATTCCATGCAGGCCATGTAT F|159|L silent|TTC>TTT|F|159 H|160|D H|160|Y YSH1 Yeast Seventy-three Homolog 779.0 0 1 0 0 -0.7963829034739254 Q06224 0.9387490153312684 0.9473130106925964 0.9489949941635132 0.012615209445357323 0.21065868437290192 1.0 0.8163999915122986 53.85370512216952 45.0 0.0 no 9145 chrXII_699121 25089 essential YLR277C 355 - TTCGTCTTTAGTCCCCATAG E|125|Q E|125|K D|124|H D|124|N YSH1 Yeast Seventy-three Homolog 779.0 0 0 0 0 -0.8706473114926283 Q06224 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.5947366952896118 0.5671601891517639 0.03717314451932907 0.10684459656476973 53.12665748393989 45.0 0.0 no 9146 chrXII_699133r 25092 essential YLR277C 340 + GTTCTTCATCCTCCTCTATG S|115|C S|115|F S|116|* S|116|L YSH1 Yeast Seventy-three Homolog 779.0 0 0 0 0 -0.2073810652932812 Q06224 0.945252001285553 0.9294660091400146 0.9298099875450134 0.057046230882406235 0.0679844319820404 0.1934085637331009 0.0430000014603138 -0.14380000531673431 0.4688000082969666 53.625967329605096 45.0 0.0 no 9147 chrXII_699190r 25094 essential YLR277C 283 + CAACCAAAGCCATTTACAGA T|96|S T|96|I silent|ACC>ACG|T|96 silent|ACC>ACT|T|96 YSH1 Yeast Seventy-three Homolog 779.0 0 0 0 0 -1.7810333858704437 Q06224 0.9491789937019348 0.9472420215606691 0.02420545369386673 0.002910831244662404 43.54670673315496 40.0 0.0 no 9148 chrXII_699233r 25095 essential YLR277C 240 + ATGCAACGGACTAACTTTCA Q|82|E Q|82|* R|83|G R|83|W YSH1 Yeast Seventy-three Homolog 779.0 0 0 0 0 -0.5262291343637668 Q06224 0.9590039849281312 0.8994590044021606 0.9448130130767822 1.0 0.003734264057129622 0.0007376366411335766 43.30530794265571 40.0 0.0 no 9149 chrXII_699247r 25096 essential YLR277C 226 + CACTTCCGTATGTGATGCAA L|77|V L|77|F P|78|A P|78|S YSH1 Yeast Seventy-three Homolog 779.0 0 1 0 0 -0.11621587375895913 Q06224 0.9512209892272948 0.9587849974632264 0.9562489986419678 0.9498909711837769 0.0872260257601738 0.007349344436079264 0.08842651546001434 0.027391115203499797 48.1132692158813 45.0 0.0 no 9150 chrXII_699298 25098 essential YLR277C 178 - TATCAGTAAGATATCGACTT silent|CTG>CTC|L|65 silent|CTG>CTA|L|65 YSH1 Yeast Seventy-three Homolog 779.0 0 0 0 0 0.5076932593016196 Q06224 38.09885815727159 30.0 0.0 no 9151 chrXII_718587 25100 essential YLR291C 856 - TACAGGGGTTCTAAATTCTC V|292|L V|292|I GCD7 General Control Derepressed 381.0 0 0 0 0 -0.4074430567763917 P32502 0.9151419997215272 0.8815600275993347 0.02257012203335762 0.032190002501010895 43.68474641440803 40.0 0.0 no 9152 chrXII_718650 25103 essential YLR291C 793 - AGTCCCCCCATTGACAAAAA silent|GGG>GGC|G|270 silent|GGG>GGA|G|270 G|270|A G|270|E GCD7 General Control Derepressed 381.0 0 0 0 0 -1.2194168184847376 P32502 0.938405990600586 0.8110049962997437 0.0 0.0 49.69284108634156 45.0 0.0 no 9153 chrXII_718657r 25105 essential YLR291C 783 + ACTAAAGCCGTTTTTGTCAA T|262|S T|262|I GCD7 General Control Derepressed 381.0 0 0 0 0 1.2322265120877975 P32502 0.9762560129165648 0.8600800037384033 0.2734952867031097 0.004822529386729002 43.591855822800426 35.0 0.0 no 9154 chrXII_718876 25112 essential YLR291C 567 - ACGGTTTTTGAATCAGGTGT V|196|L V|196|I GCD7 General Control Derepressed 381.0 0 0 0 0 0.11128877271544216 P32502 0.9589999914169312 0.9746099710464478 0.019017651677131653 0.10413339734077454 46.38076552040906 40.0 0.0 no 9155 chrXII_719209r 25116 essential YLR291C 231 + CATCCTACTGCTTTCAGTTG P|79|A P|79|S P|79|R P|79|L GCD7 General Control Derepressed 381.0 0 0 0 0 0.5268202588688672 P32502 0.9351729750633241 0.9171209931373596 0.8124330043792725 0.8144199848175049 0.033340614289045334 0.07085733860731125 0.0037656745407730345 0.004040862899273634 50.30928886035332 45.0 0.0 no 9156 chrXII_719267 25117 essential YLR291C 176 - GTTCAATAAGGTCATTAACA E|65|Q E|65|K GCD7 General Control Derepressed 381.0 0 0 0 0 0.5660071086458935 P32502 0.9896389842033386 0.9792010188102722 0.37722247838974 0.5505667328834534 37.936454029410015 30.0 0.0 no 9157 chrXII_719255 25118 essential YLR291C 188 - AATCTCTGATTTGTTCAATA D|69|H D|69|N R|68|T R|68|K GCD7 General Control Derepressed 381.0 0 0 0 0 0.11745243768833692 P32502 0.978523015975952 1.020709991455078 0.9509379863739014 1.0252100229263306 0.11075921356678008 0.4505182802677154 0.14645250141620636 0.4977923631668091 37.877825199062436 25.0 0.0 no 9158 chrXII_719410 25120 essential YLR291C 33 - ACATCAGATGTTGCCGCATT V|18|L V|18|M D|17|H D|17|N GCD7 General Control Derepressed 381.0 0 0 0 0 -0.04914571886550972 P32502 1.0161299705505369 0.9789500236511229 0.8878899812698364 0.9760419726371764 0.5415518283843994 0.04473513737320901 0.06074908375740051 0.1801973581314087 51.15571773513716 45.0 0.0 no 9159 chrXII_719436 25121 essential YLR291C 7 - TACTGAAGTGAATGCTTGAG V|9|L V|9|I GCD7 General Control Derepressed 381.0 0 0 0 0 0.5575284881322602 P32502 0.9868159890174866 1.0249600410461426 39.919431277037575 40.0 0.0 no 9160 chrXII_720925 25122 essential YLR293C 486 - TTTCTGGCCAACCATAAGAA R|168|T R|168|K GSP1 Genetic Suppressor of Prp20-1 219.0 0 0 0 0 -1.89595037031568 P32835 0.7389580011367798 0.9201679825782776 0.057511795312166214 0.16595222055912018 2.5020198822021484 -0.01829800009727478 45.434586452322826 40.0 0.0 no 9161 chrXII_720936r 25123 essential YLR293C 472 + ACTTTGAAAAGCCTTTCTTA N|158|K silent|AAC>AAT|N|158 GSP1 Genetic Suppressor of Prp20-1 219.0 0 1 0 0 0.5232804603798116 P32835 0.7102580070495605 0.07218752056360245 0.6104819774627686 41.17636489751969 30.0 0.0 no 9162 chrXII_721063r 25125 essential YLR293C 345 + AACATCCCAATTGTCTTGTG N|116|K silent|AAC>AAT|N|116 I|117|M silent|ATC>ATT|I|117 GSP1 Genetic Suppressor of Prp20-1 219.0 0 0 0 0 -0.8846979424046194 P32835 0.908900022506714 0.7934669852256775 0.02297220192849636 0.02057800441980362 0.04448999837040901 0.4544540047645569 -0.19935999810695648 46.23293591707528 40.0 0.0 no 9163 chrXII_721122 25127 essential YLR293C 289 - AACGTTCTTGTAAGTAATTC V|103|L V|103|I K|101|N silent|AAG>AAA|K|101 GSP1 Genetic Suppressor of Prp20-1 219.0 0 1 0 0 0.6988643815330451 P32835 0.8760629892349243 0.8465309739112854 0.7776790261268616 0.11315875500440598 0.1362437754869461 0.0880449190735817 0.18003399670124054 -0.6020060181617737 0.7467439770698547 0.8414595127105713 1.4974945783615112 0.5416799783706665 37.41593339297839 30.0 0.0 no 9164 chrXII_721155 25128 essential YLR293C 256 - GAACATGATGATGGCACATT M|91|I M|91|I GSP1 Genetic Suppressor of Prp20-1 219.0 0 0 0 0 -1.704772235599984 P32835 0.8556249737739563 0.8556249737739563 0.026657840237021446 0.026657840237021446 0.6509900093078613 0.6509900093078613 42.5275855704104 40.0 0.0 no 9165 chrXII_721251 25131 essential YLR293C 160 - TTCACCGAAGTTGGTGTAAA E|60|Q E|60|K G|59|A G|59|D GSP1 Genetic Suppressor of Prp20-1 219.0 0 0 0 0 0.9015497879358264 P32835 0.9855470061302184 0.9579280018806458 0.701187014579773 0.7662169933319092 0.5772836208343506 0.965947687625885 0.028585057705640793 0.013953886926174164 0.29412201046943665 0.08071599900722504 3.373420000076294 2.640307903289795 3.090488910675049 5.00485372543335 43.7196620667495 40.0 0.0 no 9166 chrXII_721281 25132 essential YLR293C 130 - ATGCACTTCGACACCAATGG silent|GTG>GTC|V|49 silent|GTG>GTA|V|49 V|49|L V|49|M GSP1 Genetic Suppressor of Prp20-1 219.0 0 0 0 0 -2.5951306757476003 P32835 0.8801479935646057 0.878591001033783 0.20580828189849854 0.016303503885865208 -0.2010820060968399 -0.10179200023412703 -0.7978000044822693 -1.333199977874756 1.4306999444961548 0.05601000040769577 48.08701177908534 50.0 0.0 yes 9167 chrXII_721308 25133 essential YLR293C 103 - GTACTTCTTTTCGAATTCAC K|40|N silent|AAG>AAA|K|40 K|39|N silent|AAG>AAA|K|39 GSP1 Genetic Suppressor of Prp20-1 219.0 0 1 0 0 -0.07667940172150395 P32835 0.9106119871139526 0.8910229802131653 0.3742520213127136 0.4099565744400024 -0.19919399917125705 0.4780960083007813 -0.08839999884366989 0.1777999997138977 -0.5590900182723999 0.4047933518886566 42.14779708503625 35.0 0.0 no 9168 chrXII_721369r 25134 essential YLR293C 39 + AAACTAGTTCTTGTCGGTGA L|15|V silent|CTA>TTA|L|15 GSP1 Genetic Suppressor of Prp20-1 219.0 0 0 0 0 0.7637788137817758 P32835 0.905282974243164 0.4188612997531891 2.7003300189971924 44.66403879211378 40.0 0.0 no 9169 chrXII_721400 25136 essential YLR293C 11 - GAACTTCACCGTTAGCAGCT V|10|L V|10|I E|9|Q E|9|K GSP1 Genetic Suppressor of Prp20-1 219.0 0 0 0 0 -0.2375680876207297 P32835 0.9628850221633912 0.9774720072746276 0.9713919758796692 0.94486802816391 0.8301122188568115 0.5071935057640076 0.22424206137657168 0.5811188220977783 0.16895200312137604 0.008070000447332859 51.9884489076145 50.0 0.0 no 9170 chrXII_721401 25137 essential YLR293C 10 - AACTTCACCGTTAGCAGCTG V|10|L V|10|I E|9|Q E|9|K GSP1 Genetic Suppressor of Prp20-1 219.0 0 0 0 0 -3.0599614596437203 P32835 0.9628850221633912 0.9774720072746276 0.9713919758796692 0.94486802816391 0.8301122188568115 0.5071935057640076 0.22424206137657168 0.5811188220977783 0.16895200312137604 0.008070000447332859 50.74705087781796 50.0 0.0 yes 9171 chrXII_724899 25138 essential YLR298C 498 - TTCTTTGGGTTATTCAACCT K|172|N silent|AAG>AAA|K|172 YHC1 Yeast Homolog of human U1C 231.0 0 0 0 0 -0.1038172215966967 Q05900 0.94167298078537 0.3052234947681427 47.041036672382575 35.0 0.0 no 9172 chrXII_725247r 25143 essential YLR298C 147 + AATCATAAAAGACGCCACAT H|51|D H|51|Y YHC1 Yeast Homolog of human U1C 231.0 0 0 0 0 0.6016662315157463 Q05900 0.9669790267944336 0.9671300053596495 0.693067193031311 0.2949981093406677 39.16496752306677 35.0 0.0 no 9173 chrXII_725164 25144 essential YLR298C 233 - GTCTTTTCTCCTTATTTGAA R|84|T R|84|K YHC1 Yeast Homolog of human U1C 231.0 0 0 0 0 -0.17750843806540428 Q05900 0.9247270226478576 0.9522929787635804 0.035096678882837296 0.8840149044990541 44.69735842221383 30.0 0.0 no 9174 chrXII_725341r 25146 essential YLR298C 53 + GAGCGTTCGTAAATCGCACT S|19|R silent|AGC>AGT|S|19 YHC1 Yeast Homolog of human U1C 231.0 0 0 0 0 -0.5542183011426518 Q05900 0.895359992980957 0.0 48.45897293971972 50.0 0.0 no 9175 chrXII_725353 25147 essential YLR298C 44 - TACGAACGCTCAACGTGTCA R|21|P R|21|H V|20|L V|20|I YHC1 Yeast Homolog of human U1C 231.0 0 0 0 0 0.7432142482524786 Q05900 0.8819800019264221 0.9198700189590454 0.9131360054016112 0.9208049774169922 0.0 0.0 0.0 0.0 46.754664370294286 50.0 0.0 no 9176 chrXII_725354 25148 essential YLR298C 43 - ACGAACGCTCAACGTGTCAT R|21|P R|21|H V|20|L V|20|I YHC1 Yeast Homolog of human U1C 231.0 0 0 0 0 -0.3823323768328456 Q05900 0.8819800019264221 0.9198700189590454 0.9131360054016112 0.9208049774169922 0.0 0.0 0.0 0.0 47.24605711126435 50.0 0.0 no 9177 chrXII_735796r 25151 high_effect YLR304C 1730 + AGACATGCCAATCTTGATTA D|578|E silent|GAC>GAT|D|578 ACO1 ACOnitase 778.0 0 1 0 0 0.4411924640363125 P19414 0.9532920122146606 0.3248576819896698 43.52024753269768 35.0 0.0 no 9178 chrXII_735831r 25153 high_effect YLR304C 1695 + AAACCATTCAAACCTTGGGA P|567|A P|567|S P|567|R P|567|L ACO1 ACOnitase 778.0 0 1 0 0 -0.3485553982809959 P19414 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.03700008988380432 0.010490933433175087 0.0014827415579929948 0.001977804582566023 43.76239463886861 40.0 0.0 no 9179 chrXII_735960 25158 high_effect YLR304C 1569 - GGCAAACCATCACCATGTGG L|529|F silent|TTG>TTA|L|529 G|528|A G|528|D ACO1 ACOnitase 778.0 0 0 0 0 -0.2255654033986699 P19414 0.9587849974632264 0.9499930143356324 0.9446240067481996 0.04544779285788536 0.5459864735603333 0.5774754285812378 51.47476577527118 55.00000000000001 0.0 no 9180 chrXII_735972r 25159 high_effect YLR304C 1554 + TTCATGTTGAAACCACCACA F|519|L silent|TTC>TTT|F|519 ACO1 ACOnitase 778.0 0 1 0 0 0.14901541868803184 P19414 0.9387490153312684 0.06034299358725548 45.61333548317293 40.0 0.0 no 9181 chrXII_736011 25162 high_effect YLR304C 1518 - TCCTTTAATTTGTCTGTTAG K|512|N silent|AAG>AAA|K|512 D|513|H D|513|N ACO1 ACOnitase 778.0 0 1 0 0 0.3011032153875857 P19414 0.9355990290641784 0.9486550092697144 0.956179976463318 0.48266455531120295 0.12983088195323944 0.5138475298881531 42.31815654910662 30.0 0.0 no 9182 chrXII_736012 25163 high_effect YLR304C 1517 - CCTTTAATTTGTCTGTTAGA K|512|N silent|AAG>AAA|K|512 ACO1 ACOnitase 778.0 0 1 0 0 0.6112183199083893 P19414 0.9355990290641784 0.48266455531120295 42.59340817280429 30.0 0.0 no 9183 chrXII_736059 25165 high_effect YLR304C 1470 - GCGAACGCAGTTACTAATTC A|497|P A|497|T silent|GCG>GCC|A|495 silent|GCG>GCA|A|495 ACO1 ACOnitase 778.0 0 0 0 0 -0.8827530873470287 P19414 0.9573720097541808 0.9523990154266356 0.008637734688818455 0.1360292285680771 44.18701215267606 45.0 0.0 no 9184 chrXII_736087 25167 high_effect YLR304C 1442 - CAACAAAAGCATGAGTTTGT V|487|L V|487|I ACO1 ACOnitase 778.0 0 0 0 0 -0.7730127708642951 P19414 0.9539830088615416 0.9574310183525084 1.0 0.4435611665248871 38.40508308421062 35.0 0.0 no 9185 chrXII_736189 25169 high_effect YLR304C 1340 - GATCCCATTGACCAATACAT D|453|H D|453|N W|452|C W|452|* ACO1 ACOnitase 778.0 0 1 0 0 -0.12012379160572885 P19414 0.9486550092697144 0.956179976463318 0.8858469724655151 0.139210507273674 0.29936113953590393 0.001731427968479693 46.97145026762189 40.0 0.0 no 9186 chrXII_736302r 25173 high_effect YLR304C 1224 + ACCATTTTCACTGTTACTCC silent|ACC>ACG|T|409 silent|ACC>ACT|T|409 T|409|S T|409|I ACO1 ACOnitase 778.0 0 0 1 Series([], Name: modification, dtype: object) 0 0.8712601408298101 P19414 0.9491789937019348 0.9472420215606691 0.2778981328010559 0.4432516992092133 49.64330030085614 40.0 0.0 no 9187 chrXII_736416 25178 high_effect YLR304C 1113 - AAACCGACTCTGACATCCAA G|377|A G|377|D G|377|R G|377|S ACO1 ACOnitase 778.0 0 0 0 0 0.3453571512308605 P19414 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.6478276252746582 0.0200077872723341 0.018969258293509483 0.2570480704307556 45.450023172447345 45.0 0.0 no 9188 chrXII_736458 25180 high_effect YLR304C 1071 - ACTTCCTTCATCTTAGAAAC V|364|L V|364|I E|363|Q E|363|K ACO1 ACOnitase 778.0 0 0 0 0 0.10731065340969262 P19414 0.9539830088615416 0.9574310183525084 0.956179976463318 0.9475290179252625 0.3690812885761261 0.2363679260015488 0.4083379805088043 0.5822802782058716 42.11410330188125 35.0 0.0 no 9189 chrXII_736462r 25181 high_effect YLR304C 1064 + TACTCCAGTTTCTAAGATGA T|356|S T|356|I P|357|A P|357|S ACO1 ACOnitase 778.0 0 1 0 0 0.2385662949368572 P19414 0.9491789937019348 0.9472420215606691 0.9562489986419678 0.9498909711837769 0.4171963930130005 0.05194107070565224 0.00854559801518917 0.16080978512763974 43.3439370553756 35.0 0.0 no 9190 chrXII_736505r 25182 high_effect YLR304C 1021 + CTCTGGAACCATACATCAAT L|342|V silent|CTG>TTG|L|342 ACO1 ACOnitase 778.0 0 0 0 0 -0.4975136542088464 P19414 0.9512209892272948 0.0037137030158191924 43.5512745266401 40.0 0.0 no 9191 chrXII_736506r 25183 high_effect YLR304C 1020 + ACTCTGGAACCATACATCAA L|342|V silent|CTG>TTG|L|342 T|341|S T|341|I ACO1 ACOnitase 778.0 0 0 0 0 -0.1925127586428776 P19414 0.9512209892272948 0.9491789937019348 0.9472420215606691 0.0037137030158191924 0.15467771887779236 0.03853157535195351 43.979893275522954 40.0 0.0 no 9192 chrXII_736573 25186 high_effect YLR304C 956 - CAGCAGATAATAGGTCCTTG A|325|P A|325|T ACO1 ACOnitase 778.0 0 1 0 0 0.04443836644639415 P19414 0.9573720097541808 0.9523990154266356 0.3421071767807007 0.06547879427671432 46.11087253930771 45.0 0.0 no 9193 chrXII_736825r 25190 high_effect YLR304C 701 + GAACGGTTGGACTTCTCCAA N|235|K silent|AAC>AAT|N|235 ACO1 ACOnitase 778.0 0 0 0 0 -0.7679192180011087 P19414 0.9439849853515624 0.09370127320289612 49.10693731491762 50.0 0.0 no 9194 chrXII_736860 25192 high_effect YLR304C 669 - AACTTAACACCTAAGATCTT K|229|N silent|AAG>AAA|K|229 ACO1 ACOnitase 778.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.4864632475152638 P19414 0.9355990290641784 0.2408426254987717 38.60101721423109 30.0 0.0 no 9195 chrXII_736901 25193 high_effect YLR304C 628 - ACGACCTGCCATAACATCAA R|216|P R|216|H G|215|A G|215|D ACO1 ACOnitase 778.0 0 0 0 0 0.3475070091488257 P19414 0.9099509716033936 0.9570810198783876 0.9499930143356324 0.9446240067481996 0.22695186734199524 0.1661694198846817 0.037891019135713584 0.2807225286960602 47.170860119571046 45.0 0.0 no 9196 chrXII_736935r 25194 high_effect YLR304C 591 + GGTCAATTGGCTATTGGTGT Q|199|E Q|199|* ACO1 ACOnitase 778.0 0 0 0 0 0.6446318756113287 P19414 0.9590039849281312 0.13090477883815765 50.51734018728193 45.0 0.0 no 9197 chrXII_736953 25195 high_effect YLR304C 576 - TGACCTAAACCACCAGCATT G|198|A G|198|D G|198|R G|198|S ACO1 ACOnitase 778.0 0 0 0 0 0.9375024768203204 P19414 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.18857619166374207 0.002866275608539581 0.0025992521550506353 0.05711480230093002 49.005784642188814 45.0 0.0 no 9198 chrXII_737026r 25197 high_effect YLR304C 500 + TATCATTCACCAAATTGTTC I|168|M silent|ATC>ATT|I|168 ACO1 ACOnitase 778.0 0 0 0 0 -0.8224280740345467 P19414 0.9598389863967896 0.0 40.128394725359726 30.0 0.0 no 9199 chrXII_737262 25201 high_effect YLR304C 267 - TCTTGACAGGCAACACGATC D|96|H D|96|N C|94|S C|94|Y ACO1 ACOnitase 778.0 0 0 0 0 -1.0227473872005208 P19414 0.9486550092697144 0.956179976463318 0.9421560168266296 0.9290120005607604 0.0023452492896467447 0.011314347386360168 0.038694217801094055 0.024463381618261337 46.72470311456874 50.0 0.0 no 9200 chrXII_737311 25203 high_effect YLR304C 218 - TCTGAATATCTTGACCATGA Q|79|H silent|CAG>CAA|Q|79 ACO1 ACOnitase 778.0 0 1 0 0 0.4222564054018306 P19414 0.9570760130882264 0.10582027584314346 42.26003316995138 35.0 0.0 no 9201 chrXII_737348 25206 high_effect YLR304C 181 - GTACAAAATCTTTTCCGCGT L|66|F silent|TTG>TTA|L|66 ACO1 ACOnitase 778.0 0 0 0 0 0.3102734399563449 P19414 0.9587849974632264 0.0426277220249176 45.36716606725071 40.0 0.0 no 9202 chrXII_737355 25207 high_effect YLR304C 174 - ATCTTTTCCGCGTAGGTAAA K|64|N silent|AAG>AAA|K|64 ACO1 ACOnitase 778.0 0 0 0 0 -0.5849491884852096 P19414 0.9355990290641784 0.0 46.997845656076784 40.0 0.0 no 9203 chrXII_739588r 25213 essential YLR305C 4253 + CCTACACGCAACCTTATACT L|1419|V silent|CTA>TTA|L|1419 H|1420|D H|1420|Y STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 -0.8357167964781536 P37297 0.9512209892272948 0.9473130106925964 0.9489949941635132 0.4803915023803711 0.06977745145559311 0.4020401835441589 48.398240772752274 45.0 0.0 no 9204 chrXII_739589r 25214 essential YLR305C 4252 + ACCTACACGCAACCTTATAC L|1419|V silent|CTA>TTA|L|1419 D|1418|E silent|GAC>GAT|D|1418 STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 0.05261996848406045 P37297 0.9512209892272948 0.9532920122146606 0.4803915023803711 0.9392066001892091 47.15131257189614 45.0 0.0 no 9205 chrXII_739668r 25217 essential YLR305C 4173 + AAACATGCTTTAATGTGTGT H|1393|D H|1393|Y STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 -0.01640978104360541 P37297 0.9473130106925964 0.9489949941635132 0.6649493575096129 0.057005658745765686 39.480182093715314 30.0 0.0 no 9206 chrXII_739667r 25218 essential YLR305C 4174 + AACATGCTTTAATGTGTGTG H|1393|D H|1393|Y A|1394|G A|1394|V STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 -0.6223890948365283 P37297 0.9473130106925964 0.9489949941635132 0.9484469890594482 0.9504740238189696 0.6649493575096129 0.057005658745765686 0.052813462913036346 0.023195980116724968 40.901588020745685 35.0 0.0 no 9207 chrXII_739818 25220 essential YLR305C 4026 - GCTCCTTCAATCTTCTCAGT G|1348|A G|1348|E A|1349|P A|1349|T STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 0.006678220802778245 P37297 0.9499930143356324 0.9438679814338684 0.9573720097541808 0.9523990154266356 0.4051767289638519 0.5097388625144958 0.21079431474208832 0.40447646379470825 53.935429951394845 45.0 0.0 no 9208 chrXII_739829 25221 essential YLR305C 4015 - CTTCTCAGTCGGAGTAAGCC E|1344|D silent|GAG>GAA|E|1344 E|1344|Q E|1344|K STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 -0.21303473364612246 P37297 0.94931298494339 0.956179976463318 0.9475290179252625 1.0 0.5291900038719177 0.5792699456214905 53.297401707123925 55.00000000000001 0.0 no 9209 chrXII_739960r 25226 essential YLR305C 3881 + AGCAGATTTATCTGTTACTA A|1295|G A|1295|V STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 0.6562892782959082 P37297 0.9484469890594482 0.9504740238189696 0.048876147717237466 0.016972806304693222 42.04587034624007 30.0 0.0 no 9210 chrXII_740004r 25230 essential YLR305C 3837 + AGACCAGTAGCGTGGCCATT P|1281|A P|1281|S P|1281|R P|1281|L STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 -0.058202430006227275 P37297 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.2062504887580872 0.1742294281721115 0.8588362336158752 0.1994861364364624 57.03935843163429 55.00000000000001 0.0 no 9211 chrXII_740033r 25231 essential YLR305C 3808 + TCACAAACGGTGCCCTAAGT T|1271|R T|1271|I I|1270|M silent|ATC>ATT|I|1270 STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 0.7688930669573204 P37297 0.9476869702339172 0.9472420215606691 0.9598389863967896 0.016329392790794373 1.0 0.0 50.035673672968294 50.0 0.0 no 9212 chrXII_740140 25237 essential YLR305C 3704 - GGCGAATCATTCTAGCGAAC R|1241|P R|1241|H STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 -1.0584406634870696 P37297 0.9099509716033936 0.9570810198783876 0.0 0.0 45.97274632915696 50.0 0.0 no 9213 chrXII_740193r 25238 essential YLR305C 3648 + TTCACGAAATGTGCGCTTTA F|1217|L silent|TTC>TTT|F|1217 T|1218|R T|1218|M STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 0.6038535509042384 P37297 0.9387490153312684 0.9476869702339172 0.9502379894256592 0.0 0.02166876755654812 0.11805829405784607 44.46652321748775 40.0 0.0 no 9214 chrXII_740379r 25239 essential YLR305C 3462 + TCTCGCGATCATGACTTAAA R|1156|G R|1156|C S|1155|C S|1155|F STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 1.1431782395523171 P37297 0.8994590044021606 0.8926740288734436 0.945252001285553 0.9294660091400146 0.14678093791007996 0.022264793515205383 0.013974171131849287 0.009970036335289478 42.88676512159896 40.0 0.0 no 9215 chrXII_740380r 25240 essential YLR305C 3461 + TTCTCGCGATCATGACTTAA S|1155|C S|1155|F R|1156|G R|1156|C STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 -0.3563406806844718 P37297 0.945252001285553 0.9294660091400146 0.8994590044021606 0.8926740288734436 0.013974171131849287 0.009970036335289478 0.14678093791007996 0.022264793515205383 44.54284574879301 40.0 0.0 no 9216 chrXII_740409r 25241 essential YLR305C 3432 + CGCTCCATTGATGACAATAT silent|CGC>CGG|R|1145 silent|CGC>CGT|R|1145 S|1146|C S|1146|F STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 -0.6394681963732769 P37297 0.945252001285553 0.9294660091400146 0.1383061558008194 0.025755373761057854 44.414861389272346 40.0 0.0 no 9217 chrXII_740720 25247 essential YLR305C 3124 - CTCTGGTGATGATGTAATAG E|1048|Q E|1048|K STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 0.19500193630263352 P37297 0.956179976463318 0.9475290179252625 0.6787543296813965 0.9462414979934692 41.00542638596795 40.0 0.0 no 9218 chrXII_740855 25249 essential YLR305C 2989 - AATCAAACCAGCCATATCCA L|1002|F silent|TTG>TTA|L|1002 STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 0.39901038781020703 P37297 0.9587849974632264 0.04385562986135483 46.78302437626189 40.0 0.0 no 9219 chrXII_740866r 25251 essential YLR305C 2975 + TGTCTCATTTGCCATGGATA silent|GTC>GTG|V|993 silent|GTC>GTT|V|993 S|994|* S|994|L STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 0.17119133799056352 P37297 0.9298099875450134 0.0076646972447633735 49.355571425101225 40.0 0.0 no 9220 chrXII_740993r 25254 essential YLR305C 2848 + TGCACAAGTCAGCTAAAGAA H|951|D H|951|Y H|951|Q silent|CAC>CAT|H|951 STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 0.374746712311016 P37297 0.9473130106925964 0.9489949941635132 0.9588389992713928 0.2454220056533813 0.9776572585105896 0.3467291593551636 41.12211939077861 40.0 0.0 no 9221 chrXII_741058r 25256 essential YLR305C 2783 + ACATTCTAAGACAACAATAT H|929|D H|929|Y S|930|C S|930|F STT4 STaurosporine and Temperature sensitive 1900.0 0 1 0 0 0.14566257666948584 P37297 0.9473130106925964 0.9489949941635132 0.945252001285553 0.9294660091400146 0.21741041541099548 1.0 0.00686175050213933 0.0036159453447908154 33.812889163446805 25.0 0.0 no 9222 chrXII_741124 25257 essential YLR305C 2720 - AGTCCAAGATACTATCAAAT D|913|H D|913|N L|912|F silent|TTG>TTA|L|912 STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 -0.22113014517797847 P37297 0.9486550092697144 0.956179976463318 0.9587849974632264 0.0 0.0 0.06783205270767212 38.28507103528285 30.0 0.0 no 9223 chrXII_741259r 25261 essential YLR305C 2582 + GCTACTTTGCCTTTCTCATA L|862|V silent|CTA>TTA|L|862 L|863|V L|863|F STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 0.030816184345774933 P37297 0.9512209892272948 0.9512209892272948 0.9587849974632264 0.08206143230199814 0.5061277151107788 0.03962632268667221 51.6757295462059 40.0 0.0 no 9224 chrXII_741260r 25262 essential YLR305C 2581 + TGCTACTTTGCCTTTCTCAT L|862|V silent|CTA>TTA|L|862 L|863|V L|863|F STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 0.1908207486637432 P37297 0.9512209892272948 0.9512209892272948 0.9587849974632264 0.08206143230199814 0.5061277151107788 0.03962632268667221 52.20769429244223 40.0 0.0 no 9225 chrXII_741347 25263 essential YLR305C 2497 - CCTAGCATATTTTCTAATCA R|839|T R|839|K A|838|P A|838|T STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 -0.015493244808441747 P37297 0.932735025882721 0.955805003643036 0.9573720097541808 0.9523990154266356 0.4520586133003235 1.0 0.1665494441986084 1.0 42.58432553856926 30.0 0.0 no 9226 chrXII_741732r 25269 essential YLR305C 2109 + GTCATCCATGGGTACCACTT silent|GTC>GTG|V|704 silent|GTC>GTT|V|704 I|705|M silent|ATC>ATT|I|705 STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 -2.818414386198932 P37297 0.9598389863967896 0.012624187394976616 55.38649361575756 50.0 0.0 yes 9227 chrXII_741733r 25270 essential YLR305C 2108 + TGTCATCCATGGGTACCACT silent|GTC>GTG|V|704 silent|GTC>GTT|V|704 I|705|M silent|ATC>ATT|I|705 STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 0.14708673723171825 P37297 0.9598389863967896 0.012624187394976616 55.025273315362476 50.0 0.0 no 9228 chrXII_741795 25271 essential YLR305C 2049 - TCATCCTTATTGATGTCCAA E|690|Q E|690|K D|689|H D|689|N STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 -0.502126419334211 P37297 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.5840023756027222 0.890690267086029 0.028249159455299374 0.31268709897994995 46.469186204180524 35.0 0.0 no 9229 chrXII_741799r 25272 essential YLR305C 2042 + TACGCCATTGGACATCAATA T|682|R T|682|M P|683|A P|683|S STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 -0.2991326059350253 P37297 0.9476869702339172 0.9502379894256592 0.9562489986419678 0.9498909711837769 0.4805369973182678 0.09507735818624496 0.24336932599544525 0.0642869770526886 44.962701863204416 40.0 0.0 no 9230 chrXII_741866 25280 essential YLR305C 1978 - AGCGATTTGATCAGCAACAC A|666|P A|666|T STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 0.9763500192551624 P37297 0.9573720097541808 0.9523990154266356 0.05272646248340607 0.07879722118377687 45.08976112201327 45.0 0.0 no 9231 chrXII_741882 25281 essential YLR305C 1962 - ACACGGGAAATCTCCGTTTG R|660|P R|660|H V|661|L V|661|I STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 -0.8267159747173405 P37297 0.9099509716033936 0.9570810198783876 0.9539830088615416 0.9574310183525084 0.26499930024147034 0.1336098164319992 0.0829685777425766 0.4427455961704254 47.26353570783135 50.0 0.0 no 9232 chrXII_741998r 25282 essential YLR305C 1843 + TATCAAAAGAATTGTTGGCC S|616|* S|616|L STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 0.8022689585304015 P37297 0.9298099875450134 0.021995216608047485 39.4164235565205 35.0 0.0 no 9233 chrXII_742279r 25285 essential YLR305C 1562 + CTCTTTGATATCTAATTGTG S|522|C S|522|F STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 0.2731128108835271 P37297 0.945252001285553 0.9294660091400146 0.0564383827149868 0.06286916136741638 38.30580374731653 30.0 0.0 no 9234 chrXII_742280 25286 essential YLR305C 1564 - CACACAATTAGATATCAAAG V|528|L V|528|M C|527|S C|527|Y STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 -0.06958606521017137 P37297 0.9539830088615416 0.9587630033493042 0.9421560168266296 0.9290120005607604 0.3100973665714264 0.02376784011721611 0.15186642110347748 0.0234919898211956 33.037492978597356 30.0 0.0 no 9235 chrXII_742318 25287 essential YLR305C 1526 - TAGCTCCACTATTGACATCA A|515|P A|515|T G|514|A G|514|E STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 0.4393607420166405 P37297 0.9573720097541808 0.9523990154266356 0.9499930143356324 0.9438679814338684 0.2910565137863159 0.6306165456771851 0.7648038268089294 1.0 47.64344937790384 40.0 0.0 no 9236 chrXII_742319 25288 essential YLR305C 1525 - AGCTCCACTATTGACATCAT A|515|P A|515|T G|514|A G|514|E STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 0.5475669904654943 P37297 0.9573720097541808 0.9523990154266356 0.9499930143356324 0.9438679814338684 0.2910565137863159 0.6306165456771851 0.7648038268089294 1.0 48.19665685714818 40.0 0.0 no 9237 chrXII_742394 25294 essential YLR305C 1450 - ACTGGCAGATGAATTTCGCA S|490|T S|490|N A|489|P A|489|T STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 0.3865798162842435 P37297 0.9512869715690612 0.9536849856376648 0.9573720097541808 0.9523990154266356 1.0 0.2259596735239029 0.2862780690193176 0.5934744477272034 47.39406417478062 45.0 0.0 no 9238 chrXII_742495r 25296 essential YLR305C 1346 + CAACTTATTAGCTGTTTCCG N|450|K silent|AAC>AAT|N|450 STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 0.672955573371578 P37297 0.9439849853515624 0.0 45.30868062652917 40.0 0.0 no 9239 chrXII_742539 25297 essential YLR305C 1305 - ACAATTGCATCTTCATTTAG V|442|L V|442|M STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 0.7206160769675435 P37297 0.9539830088615416 0.9587630033493042 0.045143112540245056 0.00900627113878727 39.98445065205607 30.0 0.0 no 9240 chrXII_742704 25300 essential YLR305C 1140 - ACAATTGCTTTTATCAAAGA V|387|L V|387|I STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 -0.5060137056380059 P37297 0.9539830088615416 0.9574310183525084 0.23822267353534696 1.0 36.28123783392823 25.0 0.0 no 9241 chrXII_743146r 25304 essential YLR305C 695 + GCTATCCAGTGCCTACTTAT L|233|V silent|CTA>TTA|L|233 S|234|C S|234|F STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 0.2712172402434709 P37297 0.9512209892272948 0.945252001285553 0.9294660091400146 0.7535212635993958 0.1403556615114212 0.04095616564154625 53.92682240945055 45.0 0.0 no 9242 chrXII_743175r 25305 essential YLR305C 666 + ATCGTCCAGTATTACGATGC I|223|M silent|ATC>ATT|I|223 silent|GTC>GTG|V|224 silent|GTC>GTT|V|224 STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 0.5060010074355562 P37297 0.9598389863967896 0.09835592657327652 48.32424655739943 45.0 0.0 no 9243 chrXII_743347r 25307 essential YLR305C 494 + ATCTGGTCTACTATCATTAG S|166|C S|166|F STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 0.1185348128905254 P37297 0.945252001285553 0.9294660091400146 0.016478920355439186 0.009532635100185871 42.81682862576434 35.0 0.0 no 9244 chrXII_743521r 25310 essential YLR305C 320 + TCTGTCCTCGAAATTCAAGT L|108|V silent|CTG>TTG|L|108 S|109|C S|109|F STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 -0.2777319686674597 P37297 0.9512209892272948 0.945252001285553 0.9294660091400146 0.7936398983001709 0.1818578839302063 0.7013882994651794 45.17821042037667 40.0 0.0 no 9245 chrXII_743544 25311 essential YLR305C 300 - ACATCTGAAATTCTTTGTCT V|107|L V|107|I D|106|H D|106|N STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 0.5299787033176298 P37297 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 0.6287828087806702 0.8465728163719177 0.04584479331970215 0.4633563458919525 40.74658102611147 30.0 0.0 no 9246 chrXII_743614r 25315 essential YLR305C 227 + AATCCCTACCACGCTCGATC I|77|M silent|ATC>ATT|I|77 P|78|A P|78|S STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 -0.11825919090354405 P37297 0.9598389863967896 0.9562489986419678 0.9498909711837769 0.16902495920658112 0.4698469340801239 0.7452872395515442 53.90144210267431 55.00000000000001 0.0 no 9247 chrXII_743784r 25318 essential YLR305C 57 + AGACTAACTAAACTTTCGAC L|21|V silent|CTA>TTA|L|21 STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 -0.5270990914145341 P37297 0.9512209892272948 0.16625669598579407 36.56393951558027 35.0 0.0 no 9248 chrXII_743346r 25320 essential YLR305C 495 + TCTGGTCTACTATCATTAGT S|166|C S|166|F L|168|V silent|CTA>TTA|L|168 STT4 STaurosporine and Temperature sensitive 1900.0 0 0 0 0 0.3949450947546439 P37297 0.945252001285553 0.9294660091400146 0.9512209892272948 0.016478920355439186 0.009532635100185871 0.12705934047698975 45.5981041442347 35.0 0.0 no 9249 chrXII_753405r 25322 essential YLR310C 3566 + AAACCCGATTAAATGCCGTG N|1190|K silent|AAC>AAT|N|1190 P|1191|A P|1191|S CDC25 Cell Division Cycle 1589.0 0 0 0 0 -0.3819942017774821 P04821 1.0 0.0 0.0 44.63800496421669 45.0 0.0 no 9250 chrXII_753455 25323 essential YLR310C 3519 - TCATCGTAACTCAGCCCTTC D|1180|H D|1180|N D|1179|H D|1179|N CDC25 Cell Division Cycle 1589.0 0 0 0 0 0.12073694612480075 P04821 0.007872303016483784 0.017284722998738292 0.007091419771313667 0.02084955759346485 53.2605907839794 50.0 0.0 no 9251 chrXII_753469r 25325 essential YLR310C 3502 + ACAACTTGTATCCTCCTGAA Y|1168|* silent|TAC>TAT|Y|1168 N|1169|K silent|AAC>AAT|N|1169 CDC25 Cell Division Cycle 1589.0 0 0 0 0 -2.1350227959366865 P04821 0.0 46.862438683325756 40.0 0.0 yes 9252 chrXII_753470r 25326 essential YLR310C 3501 + TACAACTTGTATCCTCCTGA Y|1168|* silent|TAC>TAT|Y|1168 N|1169|K silent|AAC>AAT|N|1169 CDC25 Cell Division Cycle 1589.0 0 0 0 0 -2.0759584036835186 P04821 0.0 47.89040376209334 40.0 0.0 yes 9253 chrXII_753505 25327 essential YLR310C 3469 - GGCATAAAAAAACTCTCTTG A|1163|P A|1163|T CDC25 Cell Division Cycle 1589.0 0 0 0 0 0.03887037193474874 P04821 0.03623077273368835 0.30935317277908325 35.935110558724034 35.0 0.0 no 9254 chrXII_753483 25328 essential YLR310C 3491 - ACAAGTTGTACCTGTAAATC L|1170|F silent|TTG>TTA|L|1170 CDC25 Cell Division Cycle 1589.0 0 0 0 0 0.8121988788791119 P04821 0.05975215137004852 40.31206222846856 35.0 0.0 no 9255 chrXII_753571 25329 essential YLR310C 3403 - CGCATCAACAAGTTCATGAC A|1141|P A|1141|T D|1140|H D|1140|N CDC25 Cell Division Cycle 1589.0 0 0 0 0 -0.9038420406276066 P04821 0.32785487174987793 0.2972705364227295 0.0 0.0 43.27915191832221 45.0 0.0 no 9256 chrXII_753638r 25332 essential YLR310C 3333 + AGTCTTGTCTATGACTCAAG L|1113|V L|1113|F CDC25 Cell Division Cycle 1589.0 0 0 0 0 0.06822311307735743 P04821 0.0 0.0 43.888629265607335 40.0 0.0 no 9257 chrXII_753740r 25333 essential YLR310C 3231 + GCTATCATCGATGACGAATT A|1078|G A|1078|V I|1079|M silent|ATC>ATT|I|1079 CDC25 Cell Division Cycle 1589.0 0 0 0 0 0.9957984769012228 P04821 0.4540110528469086 0.25291764736175537 0.1885397583246231 42.80102924113493 40.0 0.0 no 9258 chrXII_754079r 25336 essential YLR310C 2892 + TCTAATACACCTTTGGTCAA S|965|C S|965|F CDC25 Cell Division Cycle 1589.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.7432197394845517 P04821 0.09334419667720796 0.0985613465309143 43.49439734589197 35.0 0.0 no 9259 chrXII_754080r 25337 essential YLR310C 2891 + CTCTAATACACCTTTGGTCA S|965|C S|965|F CDC25 Cell Division Cycle 1589.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.3194693925968121 P04821 0.09334419667720796 0.0985613465309143 46.8470283525561 40.0 0.0 no 9260 chrXII_754538 25340 essential YLR310C 2436 - TTCAAAGTGTCTACAGTTAA L|818|F silent|TTG>TTA|L|818 CDC25 Cell Division Cycle 1589.0 0 0 0 0 -0.3873760828531981 P04821 0.05016231164336205 38.419139872993576 30.0 0.0 no 9261 chrXII_754718 25342 essential YLR310C 2256 - GCAATAGCATCTGCCATCTT A|759|P A|759|T CDC25 Cell Division Cycle 1589.0 0 1 0 0 0.3909933325834673 P04821 0.03602803125977516 0.048412222415208817 51.886789867280356 45.0 0.0 no 9262 chrXII_754833r 25345 essential YLR310C 2138 + TCCATTTTCGACTTTTATTA P|714|R P|714|L P|714|A P|714|S CDC25 Cell Division Cycle 1589.0 0 0 0 0 0.3858134106635415 P04821 0.0 0.0 0.0 0.0 41.78155291640274 25.0 0.0 no 9263 chrXII_755001r 25346 essential YLR310C 1970 + AGCTAAATCGATTTACGAAA A|658|G A|658|V CDC25 Cell Division Cycle 1589.0 0 0 0 0 0.4583931179622883 P04821 0.18548226356506348 1.0 35.64061903690174 30.0 0.0 no 9264 chrXII_755182 25348 essential YLR310C 1792 - AGTCAATGTATCCGTTGTAC L|603|F silent|TTG>TTA|L|603 CDC25 Cell Division Cycle 1589.0 0 1 0 0 -1.5002318368338212 P04821 0.09252626448869704 45.84411216311895 40.0 0.0 no 9265 chrXII_755210 25349 essential YLR310C 1764 - ACATTACGTTTACCGGACAA V|595|L V|595|I R|593|P R|593|H CDC25 Cell Division Cycle 1589.0 0 1 0 0 0.20348143075886926 P04821 0.20439541339874268 0.6931610703468323 0.0 0.0 44.25958620807472 40.0 0.0 no 9266 chrXII_755139r 25351 essential YLR310C 1832 + TACAGTCAATGAGAACGATA T|612|R T|612|I silent|GTC>GTG|V|613 silent|GTC>GTT|V|613 CDC25 Cell Division Cycle 1589.0 0 0 0 0 -2.5146007523083207 P04821 0.4085882306098938 0.4621661603450775 37.443441653160455 35.0 0.0 yes 9267 chrXII_755307r 25352 essential YLR310C 1664 + TGACAAGGATAACGATAATC D|556|E silent|GAC>GAT|D|556 CDC25 Cell Division Cycle 1589.0 0 1 0 0 -0.8421601885388917 P04821 0.8955262899398804 34.98070963963244 35.0 0.0 no 9268 chrXII_755395r 25353 essential YLR310C 1576 + GTCTAATCTCTTCATTGTCA L|527|V silent|CTA>TTA|L|527 CDC25 Cell Division Cycle 1589.0 0 0 0 0 0.4846888922269992 P04821 0.124619759619236 45.8329833497013 35.0 0.0 no 9269 chrXII_755434 25354 essential YLR310C 1540 - AATCTCCTTGCTGCAACTTT E|519|D silent|GAG>GAA|E|519 E|519|Q E|519|K CDC25 Cell Division Cycle 1589.0 0 0 0 0 0.22939061599598715 P04821 0.7070468068122864 0.2187035232782364 0.6003535389900208 49.06278799962763 40.0 0.0 no 9270 chrXII_755486r 25356 essential YLR310C 1485 + TCAATAGTCTTCACACAGTT S|496|* S|496|L CDC25 Cell Division Cycle 1589.0 0 0 0 0 0.5887338477719646 P04821 0.7705215215682983 43.69320749172152 35.0 0.0 no 9271 chrXII_755574r 25357 essential YLR310C 1397 + AACAGTTTATTATACTAAAA T|467|R T|467|I CDC25 Cell Division Cycle 1589.0 0 0 0 0 0.6417185466356565 P04821 0.013522918336093426 0.03266404941678047 29.2547941492399 15.0 0.0 no 9272 chrXII_755661r 25360 essential YLR310C 1310 + CCCAAGTCGCTCTTCTATAC P|438|R P|438|L P|438|A P|438|S CDC25 Cell Division Cycle 1589.0 0 0 0 0 0.2778504802917282 P04821 0.6163920164108276 0.7902218103408813 0.8833096623420715 0.7701274752616882 52.15059145770175 50.0 0.0 no 9273 chrXII_755691r 25361 essential YLR310C 1280 + AACGCAGAATATTCAATCAA T|428|R T|428|M Q|429|E Q|429|* CDC25 Cell Division Cycle 1589.0 0 1 0 0 0.9322112131858932 P04821 0.7181097865104675 0.14483709633350372 1.0 36.244603232155846 30.0 0.0 no 9274 chrXII_755838r 25363 essential YLR310C 1133 + AAGCCTTCTAATGGAAAAAC S|379|R silent|AGC>AGT|S|379 L|380|V L|380|F CDC25 Cell Division Cycle 1589.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.9803353277674568 P04821 0.27138227224349976 0.5078261494636536 0.29173293709754944 36.96297317237031 35.0 0.0 no 9275 chrXII_755880r 25364 essential YLR310C 1091 + TTCTACGAGATCGAAGCAAT S|365|C S|365|F T|366|R T|366|M CDC25 Cell Division Cycle 1589.0 0 0 0 0 1.2052086184610855 P04821 0.08005262166261673 0.12864474952220914 0.6892191171646118 0.2710326015949249 41.519834625480534 40.0 0.0 no 9276 chrXII_755925 25365 essential YLR310C 1049 - TCCTCAGATCTCTAGTATAT R|356|T R|356|K R|356|S silent|AGG>AGA|R|356 CDC25 Cell Division Cycle 1589.0 0 0 0 0 0.0557616925977692 P04821 0.5725609064102173 1.0 0.7358574271202087 46.10170072601221 35.0 0.0 no 9277 chrXII_755949 25367 essential YLR310C 1025 - TAACAAGATGATCATTGGGC V|348|L V|348|I CDC25 Cell Division Cycle 1589.0 0 0 0 0 0.1737382207756891 P04821 0.17023329436779022 0.408431887626648 40.958333447602854 40.0 0.0 no 9278 chrXII_756033 25368 essential YLR310C 941 - ATTCTGAACAGTATATATCA E|320|Q E|320|K CDC25 Cell Division Cycle 1589.0 0 0 0 0 -0.3270206699390625 P04821 0.5794389843940735 0.05108611285686493 36.71762543607889 25.0 0.0 no 9279 chrXII_756083 25369 essential YLR310C 891 - TCGGATGTTTTCGTTATCAG D|304|H D|304|N CDC25 Cell Division Cycle 1589.0 0 0 0 0 0.1584531753964597 P04821 0.11779506504535675 0.7656174898147583 45.156319384580506 40.0 0.0 no 9280 chrXII_756292 25373 essential YLR310C 682 - TGCACTCTTTGTCATATCCT A|234|P A|234|T S|233|T S|233|N CDC25 Cell Division Cycle 1589.0 0 1 0 0 -0.26693884197556683 P04821 0.3047085404396057 0.7034931182861328 0.5026739835739136 0.4821582734584808 51.05824544744058 40.0 0.0 no 9281 chrXII_756396 25376 essential YLR310C 578 - TCATCGATACGGTGTTATTG M|199|I M|199|I silent|TCG>TCC|S|198 silent|TCG>TCA|S|198 CDC25 Cell Division Cycle 1589.0 0 0 0 0 -0.3187524021012281 P04821 0.3950514495372772 0.3950514495372772 43.48157147374116 40.0 0.0 no 9282 chrXII_756482 25378 essential YLR310C 492 - CTGCTCTTGCTCGGATTTCT S|170|T S|170|N K|169|N silent|AAG>AAA|K|169 CDC25 Cell Division Cycle 1589.0 0 1 0 0 -0.0852442746449058 P04821 0.6947504878044128 0.1289728730916977 0.5302941203117371 54.58140240685003 50.0 0.0 no 9283 chrXII_756527r 25379 essential YLR310C 444 + CGCAGCAGCTTAAATAGCTT silent|CGC>CGG|R|149 silent|CGC>CGT|R|149 S|150|R silent|AGC>AGT|S|150 CDC25 Cell Division Cycle 1589.0 0 0 0 1 -0.4714907199391604 P04821 0.4953139126300812 47.76678216828128 45.0 0.0 no 9284 chrXII_756626r 25381 essential YLR310C 345 + GGCTGGTTTCCTCAAAACTT silent|GGC>GGG|G|116 silent|GGC>GGT|G|116 CDC25 Cell Division Cycle 1589.0 0 0 0 0 -0.7852021982479178 P04821 49.35289066832365 45.0 0.0 no 9285 chrXII_756732r 25384 essential YLR310C 239 + ACTTTTGTCTGTACAACAAG L|81|V L|81|F CDC25 Cell Division Cycle 1589.0 0 1 0 0 0.6394795433365075 P04821 0.5483638644218445 0.6972439885139465 40.032801806232904 35.0 0.0 no 9286 chrXII_756697r 25385 essential YLR310C 274 + TACTTAACAAAAACTCATCT L|93|V L|93|F CDC25 Cell Division Cycle 1589.0 0 0 0 0 0.5202236453012238 P04821 0.07399642467498779 0.038163304328918464 33.17973213968878 25.0 0.0 no 9287 chrXII_756733r 25386 essential YLR310C 238 + AACTTTTGTCTGTACAACAA L|81|V L|81|F CDC25 Cell Division Cycle 1589.0 0 1 0 0 0.3174047898564033 P04821 0.5483638644218445 0.6972439885139465 38.62325313332985 30.0 0.0 no 9288 chrXII_756734r 25387 essential YLR310C 237 + CAACTTTTGTCTGTACAACA L|81|V L|81|F CDC25 Cell Division Cycle 1589.0 0 1 0 0 0.4145955362628561 P04821 0.5483638644218445 0.6972439885139465 41.356926208809796 35.0 0.0 no 9289 chrXII_763029 25393 essential YLR314C 1089 - TCCACTTCGATCACCCCCCA silent|GTG>GTC|V|369 silent|GTG>GTA|V|369 D|370|H D|370|N CDC3 Cell Division Cycle 520.0 0 0 0 1 -0.4315693396989987 P32457 0.9486550092697144 0.956179976463318 0.0060613052919507035 0.012590684927999972 62.73732179051946 60.0 0.0 no 9290 chrXII_763154 25399 essential YLR314C 964 - GCTATTTTCTGCATCATCGT S|328|T S|328|N CDC3 Cell Division Cycle 520.0 0 0 0 0 1.0010359478707926 P32457 0.9512869715690612 0.9536849856376648 0.5905097723007202 0.5112378597259521 49.95233166472514 40.0 0.0 no 9291 chrXII_763319 25400 essential YLR314C 799 - TTGCATAAACTTCAGGTCCA M|272|I M|272|I CDC3 Cell Division Cycle 520.0 0 0 0 0 -0.7133299818804779 P32457 0.9553959965705872 0.9553959965705872 0.014080920256674291 0.014080920256674291 46.776814512608674 40.0 0.0 no 9292 chrXII_763456 25402 essential YLR314C 662 - AGTCAATCTCCTTAATGATC D|227|H D|227|N CDC3 Cell Division Cycle 520.0 0 0 0 0 -1.2064788911897657 P32457 0.9486550092697144 0.956179976463318 0.006941174622625113 0.1009320393204689 42.326826618975595 35.0 0.0 no 9293 chrXII_763594r 25403 essential YLR314C 521 + ATCACAAGAACAAAGGCACA S|175|* S|175|L Q|176|E Q|176|* CDC3 Cell Division Cycle 520.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.5964863090133704 P32457 0.9298099875450134 0.9590039849281312 0.03383706510066986 1.0 2.04040002822876 2.4412999153137207 39.821701356263254 40.0 0.0 no 9294 chrXII_763676 25405 essential YLR314C 442 - CTCGTAATCTTTCACTAAAT E|154|Q E|154|K CDC3 Cell Division Cycle 520.0 0 1 0 0 -0.08254438663075145 P32457 0.956179976463318 0.9475290179252625 0.17951752245426178 0.3562387824058533 38.23582468971552 30.0 0.0 no 9295 chrXII_763811r 25408 essential YLR314C 304 + TTGCTAATTTGCCCAAGCAA A|103|G A|103|V CDC3 Cell Division Cycle 520.0 0 1 0 0 0.051612220941199084 P32457 0.9484469890594482 0.9504740238189696 0.026480004191398617 0.008187131024897099 47.76314278057333 40.0 0.0 no 9296 chrXII_763835r 25409 essential YLR314C 280 + GTCAAATCAATGGTTATGTA Q|95|E Q|95|* CDC3 Cell Division Cycle 520.0 0 1 0 0 0.17586902227299614 P32457 0.9590039849281312 1.0 38.32253906050687 30.0 0.0 no 9297 chrXII_763845r 25410 essential YLR314C 270 + TTCATTCGTCGTCAAATCAA F|91|L silent|TTC>TTT|F|91 R|93|G R|93|C CDC3 Cell Division Cycle 520.0 0 1 0 0 0.2936279594482509 P32457 0.9387490153312684 0.8994590044021606 0.8926740288734436 0.5947026014328003 0.2592758536338806 0.036569464951753616 41.679422204348214 35.0 0.0 no 9298 chrXII_763876r 25414 essential YLR314C 239 + TCAAGTTCTGCCTGACCAAC Q|81|E Q|81|* CDC3 Cell Division Cycle 520.0 0 1 0 0 -0.32574140122431183 P32457 0.9590039849281312 1.0 50.58669943237329 50.0 0.0 no 9299 chrXII_763899r 25415 essential YLR314C 216 + ACCTCCTCTCAGAGCGAAAA silent|ACC>ACG|T|73 silent|ACC>ACT|T|73 T|73|S T|73|I CDC3 Cell Division Cycle 520.0 0 0 1 Series([], Name: modification, dtype: object) 0 0.16310149852904676 P32457 0.9491789937019348 0.9472420215606691 0.750984787940979 0.15831032395362854 49.587865461346276 50.0 0.0 no 9300 chrXII_763948r 25419 essential YLR314C 167 + GGCAGCTGAATCCGATGTAA A|57|G A|57|V A|58|G A|58|V CDC3 Cell Division Cycle 520.0 0 1 0 0 -1.2903062055133363 P32457 0.9484469890594482 0.9504740238189696 0.9484469890594482 0.9504740238189696 0.3247012495994568 0.3101910948753357 0.3730719685554504 0.28165683150291443 49.24749449400645 50.0 0.0 no 9301 chrXII_765457r 25425 essential YLR316C 704 + GCCGTGCTCAATGTGCTCCA P|236|R P|236|L P|236|A P|236|S TAD3 tRNA-specific Adenosine Deaminase 322.0 0 0 0 0 -1.0730258534058064 Q9URQ3 60.56701996014783 60.0 0.0 no 9302 chrXII_765660 25435 essential YLR316C 504 - TCAACAAAGACGCTCACCAT D|175|H D|175|N V|174|L V|174|I TAD3 tRNA-specific Adenosine Deaminase 322.0 0 0 0 0 0.4968887677310035 Q9URQ3 44.988713581819695 45.0 0.0 no 9303 chrXII_765703r 25436 essential YLR316C 458 + GTCGACGTTGTCTGTGAAGA S|154|W S|154|L T|155|R T|155|M TAD3 tRNA-specific Adenosine Deaminase 322.0 0 0 0 0 -1.4533490422618145 Q9URQ3 48.48210192852736 50.0 0.0 no 9304 chrXII_765751r 25437 essential YLR316C 410 + CGACTATAAAATAGACATGC D|138|E silent|GAC>GAT|D|138 TAD3 tRNA-specific Adenosine Deaminase 322.0 0 0 0 0 0.3431444389934433 Q9URQ3 35.3467290413024 35.0 0.0 no 9305 chrXII_765771 25439 essential YLR316C 393 - TCGTTCAATATTTGATCATT D|138|H D|138|N L|136|F silent|TTG>TTA|L|136 TAD3 tRNA-specific Adenosine Deaminase 322.0 0 0 0 0 0.18442424184684608 Q9URQ3 38.72153025408989 25.0 0.0 no 9306 chrXII_765815r 25441 essential YLR316C 346 + ATGCCTGGTCTGTGAAGTAC A|117|G A|117|V silent|GCC>GCG|A|117 silent|GCC>GCT|A|117 TAD3 tRNA-specific Adenosine Deaminase 322.0 0 0 0 0 0.121642099262028 Q9URQ3 51.271972443218715 50.0 0.0 no 9307 chrXII_765971 25442 essential YLR316C 193 - ACACAACACCACTTCCAAGG L|70|F silent|TTG>TTA|L|70 C|71|S C|71|Y TAD3 tRNA-specific Adenosine Deaminase 322.0 0 0 0 0 -1.1230644147705398 Q9URQ3 47.92481200896754 50.0 0.0 no 9308 chrXII_766021 25446 essential YLR316C 143 - TCAAATGTCTCAATGAAACA L|54|F silent|TTG>TTA|L|54 TAD3 tRNA-specific Adenosine Deaminase 322.0 0 0 0 0 -0.09776235545644674 Q9URQ3 35.22624949916434 30.0 0.0 no 9309 chrXII_776909r 25447 essential YLR321C 933 + ACATCCATTGTACAGGACCT T|312|R T|312|I S|313|C S|313|F SFH1 Snf Five Homolog 426.0 0 0 0 0 -0.06814533116036414 Q06168 0.9476869702339172 0.9472420215606691 0.945252001285553 0.9294660091400146 0.5475224852561951 0.1595592051744461 0.0792846828699112 0.2973462641239166 50.8792551207324 45.0 0.0 no 9310 chrXII_776997 25448 essential YLR321C 848 - TGTCTTGTAAGTTGCAGGTT D|289|H D|289|N SFH1 Snf Five Homolog 426.0 0 0 0 0 -0.3692124011849921 Q06168 0.9486550092697144 0.956179976463318 0.16026152670383453 0.8613004684448242 48.703340781770756 40.0 0.0 no 9311 chrXII_777165r 25451 essential YLR321C 677 + TGACGACTCCATATCTCCGG D|227|E silent|GAC>GAT|D|227 D|228|E silent|GAC>GAT|D|228 SFH1 Snf Five Homolog 426.0 0 0 0 0 0.6812599039346257 Q06168 0.9532920122146606 0.9532920122146606 0.4815572202205658 0.8455038070678711 51.911527221399915 55.00000000000001 0.0 no 9312 chrXII_777196 25452 essential YLR321C 649 - CCAGAGAAACTGGTCTTTTA W|223|S W|223|* SFH1 Snf Five Homolog 426.0 0 0 0 0 -3.165811113686533 Q06168 0.8858469724655151 0.0 44.09657077955746 40.0 0.0 yes 9313 chrXII_777196r 25453 essential YLR321C 646 + CCATAAAAGACCAGTTTCTC silent|ACC>ACG|T|216 silent|ACC>ACT|T|216 SFH1 Snf Five Homolog 426.0 0 0 0 0 -0.8321681802710729 Q06168 43.08490594804579 40.0 0.0 no 9314 chrXII_777224r 25455 essential YLR321C 618 + ACTTTGGATATAGAACATAT T|207|S T|207|I SFH1 Snf Five Homolog 426.0 0 0 0 0 0.1453557245316189 Q06168 0.9491789937019348 0.9472420215606691 0.5474981665611267 0.15312284231185913 35.582441047623895 25.0 0.0 no 9315 chrXII_777240r 25456 essential YLR321C 602 + AATCATGATACCAATTACTT I|202|M silent|ATC>ATT|I|202 SFH1 Snf Five Homolog 426.0 0 0 0 0 -0.1869201728161768 Q06168 0.9598389863967896 0.010920126922428608 37.35893213575133 25.0 0.0 no 9316 chrXII_777285r 25458 essential YLR321C 557 + CAACACTGATCAAGAAACGA N|187|K silent|AAC>AAT|N|187 T|188|S T|188|I SFH1 Snf Five Homolog 426.0 0 1 0 0 0.5480297832330928 Q06168 0.9439849853515624 0.9491789937019348 0.9472420215606691 0.9397545456886292 0.743503749370575 0.2121378928422928 37.15659983965054 40.0 0.0 no 9317 chrXII_777324r 25459 essential YLR321C 518 + TACTTTCATTAACGGAAAAG T|174|S T|174|I F|175|L silent|TTC>TTT|F|175 SFH1 Snf Five Homolog 426.0 0 0 0 0 0.3468238930056986 Q06168 0.9491789937019348 0.9472420215606691 0.9387490153312684 0.31054818630218506 0.01616436429321766 0.1654481589794159 33.885219345688256 30.0 0.0 no 9318 chrXII_777455r 25462 essential YLR321C 387 + AGCAATAACAACGCCAGCAA S|130|R silent|AGC>AGT|S|130 SFH1 Snf Five Homolog 426.0 0 0 0 0 0.14160293623483355 Q06168 0.9417110085487366 0.3631381988525391 44.841237688897316 45.0 0.0 no 9319 chrXII_777515r 25465 essential YLR321C 327 + TCTAACAACAAATACGATGC S|110|C S|110|F N|111|K silent|AAC>AAT|N|111 SFH1 Snf Five Homolog 426.0 0 0 0 0 0.3636288761965543 Q06168 0.945252001285553 0.9294660091400146 0.9439849853515624 0.06751126796007156 0.06830939650535582 1.0 35.96379240888558 35.0 0.0 no 9320 chrXII_777741r 25470 essential YLR321C 101 + ACAAACAAGGCAGCATAAAA Q|35|E Q|35|* T|36|R T|36|I SFH1 Snf Five Homolog 426.0 0 0 0 0 -0.8781784990050807 Q06168 0.9590039849281312 0.9476869702339172 0.9472420215606691 0.35389459133148193 0.0664798840880394 0.04310416430234909 36.621684991035245 35.0 0.0 no 9321 chrXII_777742r 25471 essential YLR321C 100 + AACAAACAAGGCAGCATAAA Q|35|E Q|35|* T|36|R T|36|I SFH1 Snf Five Homolog 426.0 0 0 0 0 0.8624987451262601 Q06168 0.9590039849281312 0.9476869702339172 0.9472420215606691 0.35389459133148193 0.0664798840880394 0.04310416430234909 36.621684991035245 35.0 0.0 no 9322 chrXII_777754r 25472 essential YLR321C 88 + TTACAATGGCTCAACAAACA T|31|R T|31|I SFH1 Snf Five Homolog 426.0 0 0 0 0 -0.3961151131018929 Q06168 0.9476869702339172 0.9472420215606691 0.4413369596004486 0.5635660886764526 38.831600557625215 35.0 0.0 no 9323 chrXII_778457r 25475 essential YLR323C 473 + CTGCAAGTTCTTACACTCGA C|159|W silent|TGC>TGT|C|159 CWC24 Complexed With Cef1p 259.0 0 0 0 0 0.4333876542763261 P53769 0.0 47.29666663171173 45.0 0.0 no 9324 chrXII_778501r 25478 essential YLR323C 429 + TGCAAAGATTACAAACAGAC C|144|W silent|TGC>TGT|C|144 CWC24 Complexed With Cef1p 259.0 0 0 0 0 -2.9929696366735046 P53769 0.0 35.15065221626861 35.0 0.0 yes 9325 chrXII_778606r 25483 essential YLR323C 324 + GAGCTGGTACTGAACATGAG L|110|V silent|CTG>TTG|L|110 CWC24 Complexed With Cef1p 259.0 0 1 0 0 0.01909495708443365 P53769 0.5144584774971008 45.30949795256152 50.0 0.0 no 9326 chrXII_778622r 25484 essential YLR323C 308 + ACCTAGTGATGACAATGAGC P|104|R P|104|L P|104|A P|104|S CWC24 Complexed With Cef1p 259.0 0 1 0 0 0.8076129245136273 P53769 0.08827519416809082 0.08896665275096892 0.8041100502014159 1.0 44.922213867813475 45.0 0.0 no 9327 chrXII_778458r 25487 essential YLR323C 472 + GCTGCAAGTTCTTACACTCG S|158|R silent|AGC>AGT|S|158 C|159|W silent|TGC>TGT|C|159 CWC24 Complexed With Cef1p 259.0 0 0 0 0 -0.2952664054852171 P53769 0.0 0.0 49.807296894452804 50.0 0.0 no 9328 chrXII_778768r 25488 essential YLR323C 162 + CAACTTTCACATGAGAATGA L|56|V L|56|F CWC24 Complexed With Cef1p 259.0 0 0 0 0 0.5865854490509694 P53769 0.34118887782096863 0.1348366141319275 38.288740466794025 35.0 0.0 no 9329 chrXII_778794 25489 essential YLR323C 139 - TGTCCTGCTATTTCCACTCT R|52|S silent|AGG>AGA|R|52 R|52|T R|52|K CWC24 Complexed With Cef1p 259.0 0 0 0 0 0.3510003737251586 P53769 0.4029345214366913 0.3771781325340271 1.0 55.61393905507424 45.0 0.0 no 9330 chrXII_800501r 25494 essential YLR336C 1873 + TTCTTGATGATATTCCAGAT L|626|V L|626|F SGD1 Suppressor of Glycerol Defect 899.0 0 0 0 0 0.3666425029091883 Q06132 0.9512209892272948 0.9587849974632264 0.17047257721424106 0.2378014773130417 42.00099489026628 30.0 0.0 no 9331 chrXII_800605r 25495 essential YLR336C 1769 + TGCTTCTTGGCGAGGAAACA A|591|G A|591|V S|592|C S|592|F SGD1 Suppressor of Glycerol Defect 899.0 0 0 0 0 -0.1389134790974769 Q06132 0.9484469890594482 0.9504740238189696 0.945252001285553 0.9294660091400146 0.08830532431602478 0.030479736626148224 0.012714984826743604 0.005460185930132866 48.68411091750698 50.0 0.0 no 9332 chrXII_800806 25499 essential YLR336C 1571 - CCATTAAAAATCTCAATCTT M|530|I M|530|I SGD1 Suppressor of Glycerol Defect 899.0 0 0 0 0 0.4274028112627534 Q06132 0.9553959965705872 0.9553959965705872 0.3541475534439087 0.3541475534439087 35.50488380499342 25.0 0.0 no 9333 chrXII_800863 25501 essential YLR336C 1514 - GTTCTGATCGTATATCTCTC E|511|Q E|511|K SGD1 Suppressor of Glycerol Defect 899.0 0 0 0 0 -2.479341244330641 Q06132 0.956179976463318 0.9475290179252625 0.3704822361469269 0.04763223975896835 46.402988512623104 40.0 0.0 yes 9334 chrXII_800916r 25503 essential YLR336C 1458 + TTACGAATTATATCGATTTC R|488|G R|488|* SGD1 Suppressor of Glycerol Defect 899.0 0 0 0 0 0.15198977100226352 Q06132 0.8994590044021606 0.009024851024150848 34.93938811000004 25.0 0.0 no 9335 chrXII_800943 25504 essential YLR336C 1434 - AACTCAGTAGTGAATTCATT E|484|D silent|GAG>GAA|E|484 E|484|Q E|484|K SGD1 Suppressor of Glycerol Defect 899.0 0 0 0 0 0.8920983579586065 Q06132 0.94931298494339 0.956179976463318 0.9475290179252625 0.0 0.0 0.0 39.181381281514966 30.0 0.0 no 9336 chrXII_801165r 25505 essential YLR336C 1209 + AAACTAAGAGGTATTGAGGT L|405|V silent|CTA>TTA|L|405 SGD1 Suppressor of Glycerol Defect 899.0 0 0 0 0 0.4365920978374688 Q06132 0.9512209892272948 0.07408186793327333 38.52526119791986 35.0 0.0 no 9337 chrXII_801229 25507 essential YLR336C 1148 - CGTCCAACAACTTCTGATTT D|389|H D|389|N L|388|F silent|TTG>TTA|L|388 SGD1 Suppressor of Glycerol Defect 899.0 0 0 0 0 0.08516563757103418 Q06132 0.9486550092697144 0.956179976463318 0.9587849974632264 0.0 0.0 0.0 44.86844147322471 40.0 0.0 no 9338 chrXII_801232r 25508 essential YLR336C 1142 + AAGCCAAAATCAGAAGTTGT S|382|R silent|AGC>AGT|S|382 Q|383|E Q|383|* SGD1 Suppressor of Glycerol Defect 899.0 0 0 0 0 0.4365372608432908 Q06132 0.9417110085487366 0.9590039849281312 0.10007045418024063 0.043053314089775085 39.717122815398454 35.0 0.0 no 9339 chrXII_801356 25509 essential YLR336C 1021 - GTCTGAAAGCTTATTCAAAG D|347|H D|347|N SGD1 Suppressor of Glycerol Defect 899.0 0 0 0 0 -1.0622070523426197 Q06132 0.9486550092697144 0.956179976463318 0.01515072491019964 0.03439124673604965 37.644957867952655 35.0 0.0 no 9340 chrXII_801430 25510 essential YLR336C 947 - CCAATTTCTTTCTCAGTGAT L|322|F silent|TTG>TTA|L|322 SGD1 Suppressor of Glycerol Defect 899.0 0 0 0 0 0.6130487317536129 Q06132 0.9587849974632264 0.3353771865367889 45.6224744112031 35.0 0.0 no 9341 chrXII_801459 25511 essential YLR336C 918 - TAGCTCTCTACAGATTGTGT S|312|T S|312|N E|311|D silent|GAG>GAA|E|311 SGD1 Suppressor of Glycerol Defect 899.0 0 0 0 0 -0.8628122736280183 Q06132 0.9512869715690612 0.9536849856376648 0.94931298494339 0.1865074187517166 0.09777750819921494 0.6460212469100952 47.92354284011657 40.0 0.0 no 9342 chrXII_801529r 25513 essential YLR336C 845 + ATCTGATAACGACAGCGTTG S|283|C S|283|F SGD1 Suppressor of Glycerol Defect 899.0 0 0 0 0 -0.483165482608997 Q06132 0.945252001285553 0.9294660091400146 0.0435558445751667 0.044411860406398766 43.581806708960706 45.0 0.0 no 9343 chrXII_801584 25515 essential YLR336C 793 - AGCTGAAAGATCATCATCCG A|271|P A|271|T SGD1 Suppressor of Glycerol Defect 899.0 0 0 0 0 -0.5170788173937861 Q06132 0.9573720097541808 0.9523990154266356 0.08993130922317505 0.14950093626976013 44.81611621571403 45.0 0.0 no 9344 chrXII_801784r 25518 essential YLR336C 590 + GCAATATTACGCAAAAAAGT Q|198|E Q|198|* SGD1 Suppressor of Glycerol Defect 899.0 0 0 0 0 0.22056814308911604 Q06132 0.9590039849281312 0.5223118066787721 34.91975886455572 30.0 0.0 no 9345 chrXII_801825 25521 essential YLR336C 552 - TCAAACGCTGATCTGTCTGA E|191|Q E|191|K silent|GCG>GCC|A|189 silent|GCG>GCA|A|189 SGD1 Suppressor of Glycerol Defect 899.0 0 0 0 0 0.4454856709142502 Q06132 0.956179976463318 0.9475290179252625 0.17843876779079434 0.36038801074028015 46.123079386553286 45.0 0.0 no 9346 chrXII_801827 25522 essential YLR336C 550 - AAACGCTGATCTGTCTGAAG silent|GCG>GCC|A|189 silent|GCG>GCA|A|189 A|189|P A|189|T SGD1 Suppressor of Glycerol Defect 899.0 0 0 0 0 0.09324846930729656 Q06132 0.9573720097541808 0.9523990154266356 0.22362808883190155 0.40432053804397583 42.498598011113295 45.0 0.0 no 9347 chrXII_801930r 25524 essential YLR336C 444 + ATACAAGGAGCTGAAAACTC Q|150|E Q|150|* SGD1 Suppressor of Glycerol Defect 899.0 0 0 0 0 -0.17589039733239348 Q06132 0.9590039849281312 0.6776661276817322 38.34710906527664 40.0 0.0 no 9348 chrXII_802142 25529 essential YLR336C 235 - TGCATTAGCACTCCTCTTTT A|85|P A|85|T SGD1 Suppressor of Glycerol Defect 899.0 0 0 0 0 -0.17135287833470952 Q06132 0.9573720097541808 0.9523990154266356 0.2773812711238861 0.5758925080299377 51.76930460715988 40.0 0.0 no 9349 chrXII_802165 25531 essential YLR336C 212 - ACGTTGGTGCTGATTTTAGC silent|ACG>ACC|T|77 silent|ACG>ACA|T|77 SGD1 Suppressor of Glycerol Defect 899.0 0 0 0 0 0.7404897529058816 Q06132 49.381570741284925 45.0 0.0 no 9350 chrXII_802240 25532 essential YLR336C 137 - CCATCTTTCTCTTTTCTTTA M|52|I M|52|I K|51|N silent|AAG>AAA|K|51 SGD1 Suppressor of Glycerol Defect 899.0 0 0 0 0 0.11083353120923847 Q06132 0.9553959965705872 0.9553959965705872 0.9355990290641784 0.2029934972524643 0.2029934972524643 0.19370542466640472 47.05120458671389 30.0 0.0 no 9351 chrXII_803310 25536 high_effect YLR337C 1777 - CACAGTCTCACTCTTATCAT V|599|L V|599|M E|597|D silent|GAG>GAA|E|597 VRP1 VeRProlin 817.0 0 0 0 0 0.4161074869676803 P37370 47.26632018525584 40.0 0.0 no 9352 chrXII_803344r 25538 high_effect YLR337C 1740 + CTACCGACTCCAACTGCATC P|582|A P|582|S P|582|R P|582|L VRP1 VeRProlin 817.0 0 0 0 0 0.21230077433870154 P37370 0.842265784740448 0.5189217329025269 0.053488250821828835 0.06154099851846695 51.856443527435495 55.00000000000001 0.0 no 9353 chrXII_803420r 25545 high_effect YLR337C 1664 + TAACGCACCACCCCCCCATA N|556|K silent|AAC>AAT|N|556 A|557|G A|557|V VRP1 VeRProlin 817.0 0 0 0 0 -0.2386431948630485 P37370 0.7607786655426025 0.3465612828731537 0.19228558242321012 60.62138544232374 60.0 0.0 no 9354 chrXII_803489 25546 high_effect YLR337C 1598 - CCAGAAACGACATACCATTT silent|CTG>CTC|L|539 silent|CTG>CTA|L|539 VRP1 VeRProlin 817.0 0 0 0 0 0.8228480973683808 P37370 43.02134712963829 40.0 0.0 no 9355 chrXII_803489r 25547 high_effect YLR337C 1595 + CCAAAATGGTATGTCGTTTC Q|533|E Q|533|* VRP1 VeRProlin 817.0 0 0 0 0 0.0849979404215559 P37370 0.8617176413536072 43.002952201205794 40.0 0.0 no 9356 chrXII_803503 25548 high_effect YLR337C 1584 - CCATTTTGGCTACTCTGTTT G|535|R G|535|S VRP1 VeRProlin 817.0 0 0 0 0 0.2694644746094824 P37370 0.06629391014575957 0.10076478123664856 50.82806301418504 40.0 0.0 no 9357 chrXII_803617r 25550 high_effect YLR337C 1467 + TTCGTGGTTGGTGGTGATAC F|490|L silent|TTC>TTT|F|490 VRP1 VeRProlin 817.0 0 0 0 0 -0.14248485730960853 P37370 0.0 50.67026011288476 50.0 0.0 no 9358 chrXII_803688r 25553 high_effect YLR337C 1396 + CTTCCTCGGCCGTAACACCT S|467|C S|467|F silent|TCC>TCG|S|467 silent|TCC>TCT|S|467 VRP1 VeRProlin 817.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.5181871033487291 P37370 0.050186637789010995 0.05523931235074997 58.375812937312965 60.0 0.0 no 9359 chrXII_803689r 25554 high_effect YLR337C 1395 + TCTTCCTCGGCCGTAACACC S|466|C S|466|F S|467|C S|467|F VRP1 VeRProlin 817.0 1 Series([], Name: modification, dtype: object) 0 0 0 -1.407977890422885 P37370 0.014570998959243298 0.011281687766313551 0.050186637789010995 0.05523931235074997 57.852491068966856 60.0 0.0 no 9360 chrXII_803702r 25555 high_effect YLR337C 1382 + ATCTTCATCCAGTTCTTCCT S|462|C S|462|F S|463|* S|463|L VRP1 VeRProlin 817.0 0 1 0 0 0.5642698832387428 P37370 0.07501059025526048 0.09301813691854477 0.32446226477622986 54.088170192801215 40.0 0.0 no 9361 chrXII_803973 25560 high_effect YLR337C 1114 - TGCTAAAGTTGGGGGAACCG A|378|P A|378|T VRP1 VeRProlin 817.0 0 0 0 0 -2.0389447534934044 P37370 0.3685571253299713 0.3126075267791748 48.3785758451774 55.00000000000001 0.0 yes 9362 chrXII_804295r 25574 high_effect YLR337C 789 + CCATCTTCTGAAGTTCCTGC P|264|R P|264|L S|265|C S|265|F VRP1 VeRProlin 817.0 0 1 0 0 -0.2642495623421344 P37370 0.02664545550942421 0.031956013292074203 0.09213215112686156 0.04147365689277649 53.34436838089749 50.0 0.0 no 9363 chrXII_804542r 25581 high_effect YLR337C 542 + ATCAGGTGCCTCTGCTCCAA S|182|* S|182|L VRP1 VeRProlin 817.0 0 0 0 0 -1.2085390597615722 P37370 0.4358682632446289 59.101667464903926 55.00000000000001 0.0 no 9364 chrXII_804614r 25584 high_effect YLR337C 470 + TCCTGATATTCCATCTTCTG P|158|R P|158|L P|158|A P|158|S VRP1 VeRProlin 817.0 0 0 0 0 0.3045474695971295 P37370 0.020543495193123814 0.02531051449477673 0.6547231078147888 0.31858468055725103 48.92222189899263 40.0 0.0 no 9365 chrXII_804755r 25594 high_effect YLR337C 329 + AAGCACTAAACCCTCTCCAT S|111|R silent|AGC>AGT|S|111 T|112|S T|112|I VRP1 VeRProlin 817.0 0 1 0 0 -0.20095606690423307 P37370 0.5469373464584351 0.7271513342857361 0.3343773484230041 49.88762572325618 45.0 0.0 no 9366 chrXII_804817 25595 high_effect YLR337C 270 - GCTAAAATATCGCCCAACTG A|97|P A|97|T VRP1 VeRProlin 817.0 0 0 0 0 0.6990391578576047 P37370 0.0 0.0 44.61569469456696 45.0 0.0 no 9367 chrXII_804845r 25600 high_effect YLR337C 239 + AGCTCCTCCAATCCCTGGGA A|81|G A|81|V P|82|A P|82|S VRP1 VeRProlin 817.0 0 0 0 0 0.6073608218584939 P37370 0.0 0.0 0.07071831077337265 0.2139870524406433 62.10155727672213 60.0 0.0 no 9368 chrXII_804849r 25601 high_effect YLR337C 235 + TGTCAGCTCCTCCAATCCCT S|80|* S|80|L A|81|G A|81|V VRP1 VeRProlin 817.0 0 0 0 0 -1.8249327230297168 P37370 0.010323838330805302 0.0 0.0 61.433376890720005 55.00000000000001 0.0 no 9369 chrXII_804880r 25602 high_effect YLR337C 204 + TCTGGTACCGTCAGTAGTAA S|69|C S|69|F VRP1 VeRProlin 817.0 0 0 0 0 0.21974879194439306 P37370 0.0623515285551548 0.0600823201239109 49.514108797149724 45.0 0.0 no 9370 chrXII_804923 25605 high_effect YLR337C 164 - CGACACCACCTCCCACGATT V|61|L V|61|I G|60|A G|60|D VRP1 VeRProlin 817.0 0 0 0 0 0.5437304907877184 P37370 0.4629946947097778 0.4420604109764099 0.06900036334991455 0.2370048463344574 56.521460723538034 60.0 0.0 no 9371 chrXII_804924 25606 high_effect YLR337C 163 - GACACCACCTCCCACGATTG V|61|L V|61|I G|60|A G|60|D VRP1 VeRProlin 817.0 0 0 0 0 0.3389422692462856 P37370 0.4629946947097778 0.4420604109764099 0.06900036334991455 0.2370048463344574 55.85082692403455 60.0 0.0 no 9372 chrXII_805024 25611 high_effect YLR337C 63 - ATCACAGATTTTGCCGGTTT silent|GTG>GTC|V|27 silent|GTG>GTA|V|27 V|27|L V|27|M VRP1 VeRProlin 817.0 0 0 0 0 0.2582486404557521 P37370 0.17301754653453827 0.17302961647510529 49.471928497888314 40.0 0.0 no 9373 chrXII_805048 25613 high_effect YLR337C 39 - GCACTACCACCTAATGCTGG S|19|T S|19|N A|20|P A|20|T VRP1 VeRProlin 817.0 0 0 0 0 0.14220868572443873 P37370 0.5632091164588928 0.4067912697792053 0.0 0.0 52.991181687402566 55.00000000000001 0.0 no 9374 chrXII_805054r 25614 high_effect YLR337C 30 + CCGCCTCCACCAGCATTAGG P|12|A P|12|S P|11|R P|11|L VRP1 VeRProlin 817.0 0 0 0 0 -0.6729544248631587 P37370 61.34191107168783 65.0 0.0 no 9375 chrXII_805057r 25615 high_effect YLR337C 27 + CCACCGCCTCCACCAGCATT P|11|A P|11|S P|10|R P|10|L VRP1 VeRProlin 817.0 0 0 0 0 -0.3704958933523727 P37370 64.22021150583134 65.0 0.0 no 9376 chrXII_805991r 25618 essential YLR340W 107 - TTCTGACTTCGTGCATTTGT R|42|T R|42|K V|41|L V|41|I RPP0 Ribosomal Protein P0 312.0 0 0 0 0 0.4618816620146245 P05317 0.932735025882721 0.955805003643036 0.9539830088615416 0.9574310183525084 0.002319464692845941 0.012944275513291359 0.0986132025718689 1.0 -1.0586999654769895 0.4880999922752381 48.9435189393077 40.0 1.0 no 9377 chrXII_805990r 25619 essential YLR340W 106 - TCTGACTTCGTGCATTTGTT R|42|T R|42|K V|41|L V|41|I RPP0 Ribosomal Protein P0 312.0 0 0 0 0 -0.7118253288322732 P05317 0.932735025882721 0.955805003643036 0.9539830088615416 0.9574310183525084 0.002319464692845941 0.012944275513291359 0.0986132025718689 1.0 -1.0586999654769895 0.4880999922752381 48.943518939307744 40.0 1.0 no 9378 chrXII_806056r 25622 essential YLR340W 172 - TCTGATGGCTCTTCTAACCA R|64|T R|64|K RPP0 Ribosomal Protein P0 312.0 0 1 0 0 -0.5170329897357634 P05317 0.932735025882721 0.955805003643036 0.011900234036147594 0.7647028565406799 50.61252343563427 45.0 1.0 no 9379 chrXII_806118r 25625 essential YLR340W 234 - CCAACGTTACCTTTGACAAA G|85|R G|85|S V|84|L V|84|I RPP0 Ribosomal Protein P0 312.0 0 1 0 0 -0.4025338077091083 P05317 0.941340982913971 0.951104998588562 0.9539830088615416 0.9574310183525084 0.003562749130651355 0.07860182970762253 0.07241205126047134 0.1760326474905014 43.46783920195219 40.0 1.0 no 9380 chrXII_806118 25626 essential YLR340W 231 + CCTTTTGTCAAAGGTAACGT P|78|R P|78|L RPP0 Ribosomal Protein P0 312.0 0 1 0 0 -0.3684601331682565 P05317 0.9432820081710817 0.9430609941482544 0.01496818382292986 0.004967278335243464 44.549656248118474 40.0 1.0 no 9381 chrXII_806160r 25627 essential YLR340W 276 - ACGTTCTTGATTTCAGTCAA V|99|L V|99|I K|97|N silent|AAG>AAA|K|97 RPP0 Ribosomal Protein P0 312.0 0 1 0 0 -0.03636714737943912 P05317 0.9539830088615416 0.9574310183525084 0.9355990290641784 0.3354974091053009 0.4718522727489472 0.015883138403296467 44.11361501427541 35.0 1.0 no 9382 chrXII_806224 25629 essential YLR340W 337 + CCGTTGCTCCAGAAGACATC silent|GCC>GCG|A|113 silent|GCC>GCT|A|113 A|115|G A|115|V RPP0 Ribosomal Protein P0 312.0 0 0 0 0 -0.33405819596925745 P05317 0.9484469890594482 0.9504740238189696 0.009330252185463905 0.002813933417201042 52.22422504238017 55.00000000000001 1.0 no 9383 chrXII_806323r 25632 essential YLR340W 439 - AACAATTTCAATGGTACCTC V|153|L V|153|I RPP0 Ribosomal Protein P0 312.0 0 1 0 0 -2.3176231002026704 P05317 0.9539830088615416 0.9574310183525084 0.5685707926750183 0.9461688995361328 -0.8546000123023987 -1.204200029373169 40.83588808675949 35.0 1.0 yes 9384 chrXII_806415 25634 essential YLR340W 528 + AACATCTCTCCATTCACTTT N|177|K silent|AAC>AAT|N|177 I|178|M silent|ATC>ATT|I|178 RPP0 Ribosomal Protein P0 312.0 0 0 0 0 0.17582097422851695 P05317 0.9439849853515624 0.9598389863967896 0.15949232876300812 0.0017226828495040536 46.59683864163679 35.0 1.0 no 9385 chrXII_806547 25636 essential YLR340W 660 + GCTTCTATCTCTTTGGCTAT A|221|G A|221|V S|222|C S|222|F RPP0 Ribosomal Protein P0 312.0 0 0 0 0 -0.2442035446022193 P05317 0.9484469890594482 0.9504740238189696 0.945252001285553 0.9294660091400146 0.055807754397392266 0.033666878938674934 0.06652027368545532 0.002069860929623246 51.24118996969452 40.0 1.0 no 9386 chrXII_824526r 25639 essential YLR347C 1865 + TTCAGCTCTAGCTGCTTCTT S|623|* S|623|L A|624|G A|624|V KAP95 KAryoPherin 861.0 0 0 0 0 -0.1053088121494273 Q06142 0.9298099875450134 0.9484469890594482 0.9504740238189696 0.007424985524266958 0.027021052315831184 0.012834844179451466 55.030244009100564 45.0 0.0 no 9387 chrXII_824602r 25640 essential YLR347C 1789 + TGCTTATGGGACTGTTCTTC L|598|V L|598|F KAP95 KAryoPherin 861.0 0 0 0 0 0.9356884271851541 Q06142 0.9512209892272948 0.9587849974632264 0.07733713090419769 0.04775358736515045 49.89424883471287 45.0 0.0 no 9388 chrXII_824647 25643 essential YLR347C 1747 - ACTTGGACTTTTTCTAATAA S|589|T S|589|N KAP95 KAryoPherin 861.0 0 0 0 0 0.1895388264593581 Q06142 0.9512869715690612 0.9536849856376648 0.595646858215332 0.5216756463050842 37.3734911404041 25.0 0.0 no 9389 chrXII_824903 25649 essential YLR347C 1491 - ATCAAACCATCTACAAGAGC L|503|F silent|TTG>TTA|L|503 G|502|A G|502|D KAP95 KAryoPherin 861.0 0 0 0 0 -0.1383320940557919 Q06142 0.9587849974632264 0.9499930143356324 0.9446240067481996 0.013600675389170648 1.0 0.11111392080783844 41.675989607822494 40.0 0.0 no 9390 chrXII_824909r 25650 essential YLR347C 1482 + TTCTATCCCGCTCTTGTAGA F|495|L silent|TTC>TTT|F|495 P|497|A P|497|S KAP95 KAryoPherin 861.0 0 0 0 0 1.1215125579043812 Q06142 0.9387490153312684 0.9562489986419678 0.9498909711837769 0.038172196596860886 0.3281241357326508 0.2916518151760101 53.64958594891328 45.0 0.0 no 9391 chrXII_824994 25652 essential YLR347C 1400 - AACAGTTTGTGGCCACTTTT C|473|S C|473|Y KAP95 KAryoPherin 861.0 0 0 0 0 0.8196824284958617 Q06142 0.9421560168266296 0.9290120005607604 0.09886258840560913 0.0026718045119196177 49.427629142242154 40.0 0.0 no 9392 chrXII_825028r 25653 essential YLR347C 1363 + TCGTTCAAGCTTGTTTAATT silent|GTC>GTG|V|455 silent|GTC>GTT|V|455 Q|457|E Q|457|* KAP95 KAryoPherin 861.0 0 0 0 0 1.0844241355165656 Q06142 0.9590039849281312 0.5388054251670837 41.9889748304513 30.0 0.0 no 9393 chrXII_825029r 25654 essential YLR347C 1362 + GTCGTTCAAGCTTGTTTAAT silent|GTC>GTG|V|455 silent|GTC>GTT|V|455 Q|457|E Q|457|* KAP95 KAryoPherin 861.0 0 0 0 0 0.6699724506179233 Q06142 0.9590039849281312 0.5388054251670837 44.26557514344249 35.0 0.0 no 9394 chrXII_825103 25656 essential YLR347C 1291 - TCTACCAATACACCAAGCAG R|437|T R|437|K G|436|A G|436|D KAP95 KAryoPherin 861.0 0 0 0 0 -0.9315924889862794 Q06142 0.932735025882721 0.955805003643036 0.9499930143356324 0.9446240067481996 0.007611956913024187 0.046502020210027695 0.053403966128826134 0.014954067766666412 45.85428191880214 45.0 0.0 no 9395 chrXII_825152 25657 essential YLR347C 1242 - TTCATTAAATTCAAAATAGA M|420|I M|420|I KAP95 KAryoPherin 861.0 0 0 0 0 0.029525399181377587 Q06142 0.9553959965705872 0.9553959965705872 0.28346315026283264 0.28346315026283264 28.546659698245836 15.0 0.0 no 9396 chrXII_825217 25659 essential YLR347C 1177 - GCCATCCATAATGGAACCAA G|399|R G|399|S G|399|A G|399|D KAP95 KAryoPherin 861.0 0 0 0 0 -0.1617891833613998 Q06142 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 47.85017893758578 45.0 0.0 no 9397 chrXII_825256 25660 essential YLR347C 1138 - ACGATTCCTCCAGTTGTCAG R|386|P R|386|H R|384|S silent|AGG>AGA|R|384 KAP95 KAryoPherin 861.0 0 0 0 0 0.021098448873552226 Q06142 0.9099509716033936 0.9570810198783876 0.9087679982185364 0.005344327539205551 0.00584862707182765 0.03799131140112877 53.109550552241785 50.0 0.0 no 9398 chrXII_825399 25662 essential YLR347C 995 - CTTCATTTTGTCTCGTTAGA E|338|Q E|338|K KAP95 KAryoPherin 861.0 0 0 0 0 1.004220779140837 Q06142 0.956179976463318 0.9475290179252625 0.014891334809362888 0.011595097370445728 45.47948539510827 35.0 0.0 no 9399 chrXII_825461 25663 essential YLR347C 933 - GCGAAATTATAACTCTGTAA A|318|P A|318|T KAP95 KAryoPherin 861.0 0 0 0 0 0.6632911639953671 Q06142 0.9573720097541808 0.9523990154266356 0.011111874133348463 0.01427510008215904 36.15181870986624 30.0 0.0 no 9400 chrXII_825697 25668 essential YLR347C 697 - TTCTATATCTTCAGCTTGAG E|239|Q E|239|K KAP95 KAryoPherin 861.0 0 0 0 0 0.14749044553422322 Q06142 0.956179976463318 0.9475290179252625 0.5760775208473206 0.8701635599136353 43.50633820599222 35.0 0.0 no 9401 chrXII_825720 25669 essential YLR347C 674 - CTTCACAGACGACTTGCATA E|231|Q E|231|K C|230|S C|230|Y KAP95 KAryoPherin 861.0 0 0 0 0 0.6728058059086017 Q06142 0.956179976463318 0.9475290179252625 0.9421560168266296 0.9290120005607604 0.0 0.0 0.0 0.0 46.41485674232014 45.0 0.0 no 9402 chrXII_825624r 25670 essential YLR347C 767 + TACATTTATGAAACCTTACA T|257|R T|257|I KAP95 KAryoPherin 861.0 0 0 0 0 0.6869080158970831 Q06142 0.9476869702339172 0.9472420215606691 0.04768304899334908 0.01998327486217022 36.66498298259569 25.0 0.0 no 9403 chrXII_825837 25671 essential YLR347C 557 - TTTCCGTAGATTGCGCACCC E|192|Q E|192|K silent|ACG>ACC|T|191 silent|ACG>ACA|T|191 KAP95 KAryoPherin 861.0 0 0 0 0 -0.2746205396002673 Q06142 0.956179976463318 0.9475290179252625 0.0 0.0 56.49318166258422 55.00000000000001 0.0 no 9404 chrXII_825840r 25673 essential YLR347C 551 + TGTCCAGGGTGCGCAATCTA silent|GTC>GTG|V|185 silent|GTC>GTT|V|185 Q|186|E Q|186|* KAP95 KAryoPherin 861.0 0 0 0 0 -0.9247969720766758 Q06142 0.9590039849281312 0.06800203025341034 55.848749243951254 55.00000000000001 0.0 no 9405 chrXII_825854r 25674 essential YLR347C 537 + ATCTTAATCGCTATTGTCCA I|180|M silent|ATC>ATT|I|180 KAP95 KAryoPherin 861.0 0 0 0 0 0.1137240358046016 Q06142 0.9598389863967896 0.0 46.2506465178546 35.0 0.0 no 9406 chrXII_825855r 25675 essential YLR347C 536 + TATCTTAATCGCTATTGTCC I|180|M silent|ATC>ATT|I|180 KAP95 KAryoPherin 861.0 0 0 0 0 -0.5650432703894848 Q06142 0.9598389863967896 0.0 44.38918377916559 35.0 0.0 no 9407 chrXII_825891 25676 essential YLR347C 503 - AAACTAAGGCTTGACTTTGA V|174|L V|174|I KAP95 KAryoPherin 861.0 0 0 0 0 0.3593421264484161 Q06142 0.9539830088615416 0.9574310183525084 0.338952898979187 0.40275692939758295 39.959530684591535 35.0 0.0 no 9408 chrXII_825919 25677 essential YLR347C 475 - ACTTTCACACATATAACCCA S|165|T S|165|N E|164|Q E|164|K KAP95 KAryoPherin 861.0 0 0 0 0 -0.7038116286968127 Q06142 0.9512869715690612 0.9536849856376648 0.956179976463318 0.9475290179252625 0.4067072868347168 0.12889228761196134 0.0 0.0 44.63910304056543 35.0 0.0 no 9409 chrXII_825995 25679 essential YLR347C 399 - ACCATAATTTTCATCAACTC M|139|I M|139|I V|140|L V|140|I KAP95 KAryoPherin 861.0 0 0 0 0 -0.2385149817749664 Q06142 0.9553959965705872 0.9553959965705872 0.9539830088615416 0.9574310183525084 0.10374830663204193 0.10374830663204193 0.7573060393333435 0.1175721362233162 39.93760167671485 30.0 0.0 no 9410 chrXII_826008 25680 essential YLR347C 386 - TCAACTCTGGCCATGCGCCA L|135|F silent|TTG>TTA|L|135 E|134|D silent|GAG>GAA|E|134 KAP95 KAryoPherin 861.0 0 0 0 0 -1.86538804237261 Q06142 0.9587849974632264 0.94931298494339 0.0 1.0 59.068732101327726 60.0 0.0 no 9411 chrXII_826053r 25684 essential YLR347C 338 + TGCAGCAGCTCAATTGATTG A|114|G A|114|V A|115|G A|115|V KAP95 KAryoPherin 861.0 0 0 0 0 0.1710980423869562 Q06142 0.9484469890594482 0.9504740238189696 0.9484469890594482 0.9504740238189696 0.31070008873939514 0.9668005108833312 0.04696052148938179 0.015125119127333162 47.26046475427478 45.0 0.0 no 9412 chrXII_826067 25685 essential YLR347C 327 - GCTGCTGCATTTGCTATACG A|116|P A|116|T A|115|P A|115|T KAP95 KAryoPherin 861.0 0 0 0 0 -0.6023583228221185 Q06142 0.9573720097541808 0.9523990154266356 0.9573720097541808 0.9523990154266356 0.026869798079133037 0.01928190141916275 0.02156520448625088 0.022709965705871586 51.60839573044285 50.0 0.0 no 9413 chrXII_826101r 25686 essential YLR347C 290 + AACTAACGCGCTGACCGCAT T|98|S T|98|I N|99|K silent|AAC>AAT|N|99 KAP95 KAryoPherin 861.0 0 1 0 0 0.5795669623032906 Q06142 0.9491789937019348 0.9472420215606691 0.9439849853515624 0.8410298228263855 0.16849856078624725 0.926990270614624 50.59451607746996 55.00000000000001 0.0 no 9414 chrXII_826162r 25688 essential YLR347C 229 + CGCAGCAATTTGCACAACGT Q|78|E Q|78|* Q|79|E Q|79|* KAP95 KAryoPherin 861.0 0 1 0 0 -0.948456063765624 Q06142 0.9590039849281312 0.9590039849281312 1.0 1.0 48.434800387768576 50.0 0.0 no 9415 chrXII_826180 25689 essential YLR347C 214 - CTGCGTCTTGACTGAGTCCT silent|ACG>ACC|T|77 silent|ACG>ACA|T|77 K|76|N silent|AAG>AAA|K|76 KAP95 KAryoPherin 861.0 0 0 1 Series([], Name: modification, dtype: object) 0 0.0740145415065546 Q06142 0.9355990290641784 0.12213493883609773 55.826458867387544 55.00000000000001 0.0 no 9416 chrXII_826289r 25692 essential YLR347C 102 + GACAACTTCTTACAATTTGC D|35|E silent|GAC>GAT|D|35 N|36|K silent|AAC>AAT|N|36 KAP95 KAryoPherin 861.0 0 0 0 0 0.43149692868930817 Q06142 0.9532920122146606 0.9439849853515624 1.0 0.054813094437122345 40.181793787883976 35.0 0.0 no 9417 chrXII_826338 25694 essential YLR347C 56 - CACTAGTCAACCGAATGTTT S|25|T S|25|N KAP95 KAryoPherin 861.0 0 0 0 0 0.3920814037737717 Q06142 0.9512869715690612 0.9536849856376648 0.016320427879691124 0.005530046299099922 43.888428002518815 40.0 0.0 no 9418 chrXII_838381 25696 essential YLR355C 853 - TTCGTTGAAAGCTTCAGATG E|291|Q E|291|K ILV5 IsoLeucine-plus-Valine requiring 395.0 0 0 0 0 -6.563180179471478 P06168 0.956179976463318 0.9475290179252625 0.15335537493228912 0.06359641999006271 42.035062382794884 40.0 0.0 yes 9419 chrXII_838500 25698 essential YLR355C 734 - CTTCTCTTTCGAAAGTGGTT E|251|Q E|251|K R|250|T R|250|K ILV5 IsoLeucine-plus-Valine requiring 395.0 0 1 0 0 -2.74294358547965 P06168 0.956179976463318 0.9475290179252625 0.932735025882721 0.955805003643036 0.0 0.0 0.18788307905197146 1.0 45.59700117007935 40.0 0.0 yes 9420 chrXII_838551r 25699 essential YLR355C 680 + TCACGAAAAGGCCCAAGCTT H|228|Q silent|CAC>CAT|H|228 H|228|D H|228|Y ILV5 IsoLeucine-plus-Valine requiring 395.0 0 1 0 0 0.1766372644718741 P06168 0.9588389992713928 0.9473130106925964 0.9489949941635132 0.5816336274147034 0.6007281541824341 0.05059211701154709 48.69246846908578 50.0 0.0 no 9421 chrXII_838619r 25702 essential YLR355C 612 + TCTTTGTTCAAGGAAGGTCG S|205|C S|205|F ILV5 IsoLeucine-plus-Valine requiring 395.0 0 1 0 0 -1.735500400118826 P06168 0.945252001285553 0.9294660091400146 0.015888018533587456 0.021421002224087715 45.46659949613428 45.0 0.0 no 9422 chrXII_838629r 25703 essential YLR355C 602 + AACTGTCAGATCTTTGTTCA T|202|S T|202|I silent|GTC>GTG|V|203 silent|GTC>GTT|V|203 ILV5 IsoLeucine-plus-Valine requiring 395.0 0 1 0 0 0.2966689696120115 P06168 0.9491789937019348 0.9472420215606691 0.6389139890670776 0.02635808847844601 44.44161120461274 35.0 0.0 no 9423 chrXII_838646 25704 essential YLR355C 588 - ACAGTTCTACCGGAACCCTT V|203|L V|203|I R|201|T R|201|K ILV5 IsoLeucine-plus-Valine requiring 395.0 0 0 0 0 0.7329604599199175 P06168 0.9539830088615416 0.9574310183525084 0.932735025882721 0.955805003643036 0.051117122173309326 0.027331139892339703 0.4869402945041657 0.9957029819488524 -1.0072000026702879 -1.4199999570846558 53.37778529063724 50.0 0.0 no 9424 chrXII_838764r 25708 essential YLR355C 467 + TATCAAGCCATTGTTGACCA I|157|M silent|ATC>ATT|I|157 ILV5 IsoLeucine-plus-Valine requiring 395.0 0 1 0 0 -1.4756757295774392 P06168 0.9598389863967896 0.0062661124393343925 -2.986000061035156 48.076707029615704 40.0 0.0 no 9425 chrXII_838862 25711 essential YLR355C 372 - ACAGTGAACAAGTTCTTGCC V|131|L V|131|I ILV5 IsoLeucine-plus-Valine requiring 395.0 0 1 0 0 -0.4148445256114748 P06168 0.9539830088615416 0.9574310183525084 0.28033652901649475 0.5760582685470581 46.91864215829839 45.0 0.0 no 9426 chrXII_838912r 25715 essential YLR355C 319 + TCCGTAAAGATGGTGCTTCT R|108|G R|108|C silent|GTC>GTG|V|107 silent|GTC>GTT|V|107 ILV5 IsoLeucine-plus-Valine requiring 395.0 0 0 0 0 -2.0100607019584182 P06168 0.8994590044021606 0.8926740288734436 0.009881456382572651 0.0014843973331153393 48.86454380699774 45.0 0.0 yes 9427 chrXII_838922r 25716 essential YLR355C 309 + ATCATTGGTGTCCGTAAAGA I|104|M silent|ATC>ATT|I|104 ILV5 IsoLeucine-plus-Valine requiring 395.0 0 0 0 0 -1.645585185440551 P06168 0.9598389863967896 0.03110064379870892 -0.6424000263214111 45.451769879990536 40.0 0.0 no 9428 chrXII_838971 25718 essential YLR355C 263 - TCAAACCTTGACCGTAACCT L|94|F silent|TTG>TTA|L|94 G|93|A G|93|D ILV5 IsoLeucine-plus-Valine requiring 395.0 0 0 0 0 -2.1125291620700453 P06168 0.9587849974632264 0.9499930143356324 0.9446240067481996 0.15710750222206116 1.0 0.010915723629295826 0.2318000048398972 47.733794467112496 45.0 0.0 yes 9429 chrXII_838997r 25719 essential YLR355C 234 + ACTTTTGCTTTGATCGGTTA T|79|S T|79|I ILV5 IsoLeucine-plus-Valine requiring 395.0 0 1 0 0 -0.34864473590869594 P06168 0.9491789937019348 0.9472420215606691 0.039871599525213235 0.129091277718544 46.347399433233356 35.0 0.0 no 9430 chrXII_839003r 25720 essential YLR355C 228 + AACGACACTTTTGCTTTGAT N|77|K silent|AAC>AAT|N|77 D|78|E silent|GAC>GAT|D|78 ILV5 IsoLeucine-plus-Valine requiring 395.0 0 1 0 0 -0.08849027192789755 P06168 0.9439849853515624 0.9532920122146606 0.17378707230091095 1.0 42.6761931924014 35.0 0.0 no 9431 chrXII_839125 25725 essential YLR355C 109 - GATCATTGGCTTAACGAAAC M|42|I M|42|I ILV5 IsoLeucine-plus-Valine requiring 395.0 0 0 0 0 -0.015363078049481059 P06168 0.9553959965705872 0.9553959965705872 39.74300035776992 40.0 0.0 no 9432 chrXII_839181r 25728 essential YLR355C 50 + TGCTAAGAGAACCTTTGCTT A|18|G A|18|V ILV5 IsoLeucine-plus-Valine requiring 395.0 0 0 0 0 0.2814296448460212 P06168 0.9484469890594482 0.9504740238189696 45.96732751735823 40.0 0.0 no 9433 chrXII_839194 25729 essential YLR355C 40 - TCTCTTAGCAGTGATGACAC K|19|N silent|AAG>AAA|K|19 R|20|T R|20|K ILV5 IsoLeucine-plus-Valine requiring 395.0 0 0 0 0 -0.4005217818778828 P06168 0.9355990290641784 0.932735025882721 0.955805003643036 46.9402852845791 45.0 0.0 no 9434 chrXII_844314 25731 essential YLR359W 32 + GTCTTCTAGATATGCCTCCA S|12|C S|12|F S|13|C S|13|F ADE13 ADEnine requiring 482.0 0 0 0 0 0.14276777571438254 Q05911 0.945252001285553 0.9294660091400146 0.945252001285553 0.9294660091400146 0.019022809341549873 0.014401367865502834 0.008499940857291222 0.007612857036292553 -0.03153999894857406 -1.057800054550171 53.769888047496245 45.0 1.0 no 9435 chrXII_844331r 25732 essential YLR359W 52 - AAACGTTGCTGACATTTCCT silent|ACG>ACC|T|23 silent|ACG>ACA|T|23 ADE13 ADEnine requiring 482.0 0 0 0 0 -0.21109966230016566 Q05911 46.14222641203793 40.0 1.0 no 9436 chrXII_844626 25738 essential YLR359W 344 + TGCTGATCTAATCTTTATTA A|116|G A|116|V ADE13 ADEnine requiring 482.0 0 0 0 0 0.222105787023694 Q05911 0.9484469890594482 0.9504740238189696 0.2427612692117691 0.023246550932526592 38.92962698519341 25.0 1.0 no 9437 chrXII_844716 25739 essential YLR359W 434 + ATACAAGGATTTGCCTGTAT Y|146|* silent|TAC>TAT|Y|146 ADE13 ADEnine requiring 482.0 0 0 0 0 -0.4368794393470259 Q05911 44.36321682828106 35.0 1.0 no 9438 chrXII_844755 25741 essential YLR359W 473 + ACCAGCACAATTAACGACCT P|159|R P|159|L P|159|A P|159|S ADE13 ADEnine requiring 482.0 0 1 0 0 -0.23371741945795285 Q05911 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.014295256696641443 0.009351493790745735 0.11945285648107527 0.19214557111263275 46.988093384143035 45.0 1.0 no 9439 chrXII_844756 25742 essential YLR359W 474 + CCAGCACAATTAACGACCTT P|159|R P|159|L A|160|G A|160|V ADE13 ADEnine requiring 482.0 0 1 0 0 -1.0566911206218101 Q05911 0.9432820081710817 0.9430609941482544 0.9484469890594482 0.9504740238189696 0.014295256696641443 0.009351493790745735 0.0 0.0 0.5051000118255615 2.235359907150269 46.819245564006046 45.0 1.0 no 9440 chrXII_844848 25743 essential YLR359W 566 + TATCGGTCTACGTGGTGTTA I|190|M silent|ATC>ATT|I|190 ADE13 ADEnine requiring 482.0 0 0 0 0 -0.7614090597735459 Q05911 0.9598389863967896 0.2632681131362915 -1.7239400148391724 49.57883588031206 45.0 1.0 no 9441 chrXII_844908r 25746 essential YLR359W 629 - CAACTTTATCATGATTACCA V|216|L V|216|I ADE13 ADEnine requiring 482.0 0 0 0 0 -0.3414022091205405 Q05911 0.9539830088615416 0.9574310183525084 0.041928526014089584 0.28172507882118225 -0.8137199878692627 1.0860999822616575 40.21215679338758 30.0 1.0 no 9442 chrXII_845127 25748 essential YLR359W 845 + ACAAATCGGATCCTCTGCTA Q|283|E Q|283|* I|284|M silent|ATC>ATT|I|284 ADE13 ADEnine requiring 482.0 0 1 0 0 -1.003142279765521 Q05911 0.9590039849281312 0.9598389863967896 0.007347223814576864 0.003407300217077136 0.10531999915838243 47.9481119808994 45.0 1.0 no 9443 chrXII_845113r 25749 essential YLR359W 834 - CCGATTTGTGATTTCTCAAA G|285|R G|285|R ADE13 ADEnine requiring 482.0 0 1 0 0 -0.5051727981257911 Q05911 0.941340982913971 0.941340982913971 0.0 0.0 42.440858407831115 35.0 1.0 no 9444 chrXII_845163r 25750 essential YLR359W 884 - ACACTCTCTCACAACGCATT V|301|L V|301|M silent|GTG>GTC|V|301 silent|GTG>GTA|V|301 ADE13 ADEnine requiring 482.0 0 0 0 0 -0.9299029101607484 Q05911 0.9539830088615416 0.9587630033493042 0.1618354320526123 0.17750200629234314 48.22056392286413 45.0 1.0 no 9445 chrXII_845164r 25751 essential YLR359W 885 - CACACTCTCTCACAACGCAT silent|GTG>GTC|V|301 silent|GTG>GTA|V|301 V|301|L V|301|M ADE13 ADEnine requiring 482.0 0 0 0 0 0.42169685291983583 Q05911 0.9539830088615416 0.9587630033493042 0.1618354320526123 0.17750200629234314 49.19424803573304 50.0 1.0 no 9446 chrXII_845185 25752 essential YLR359W 903 + TGCTCCTTGGCTAGACACTT C|302|W silent|TGC>TGT|C|302 S|303|C S|303|F ADE13 ADEnine requiring 482.0 0 0 0 0 0.12235461877308093 Q05911 0.9286419749259948 0.945252001285553 0.9294660091400146 0.011823470704257488 0.011237013153731823 0.004252608399838209 4.444459915161133 54.81919695717784 50.0 1.0 no 9447 chrXII_845228 25753 essential YLR359W 946 + TTCAAACTGCATCCGTTCAA Q|317|E Q|317|* T|318|S T|318|I ADE13 ADEnine requiring 482.0 0 0 0 0 -0.07876601884463626 Q05911 0.9590039849281312 0.9491789937019348 0.9472420215606691 0.2826589345932007 0.04949861764907837 0.2879351079463959 45.5144200399867 40.0 1.0 no 9448 chrXII_845332 25755 essential YLR359W 1050 + ACTTTGTTGAACATCTCATC T|351|S T|351|I ADE13 ADEnine requiring 482.0 0 0 0 0 0.4871088071680579 Q05911 0.9491789937019348 0.9472420215606691 0.20951612293720245 0.74610435962677 42.20308443378104 35.0 1.0 no 9449 chrXII_859617 25756 high_effect YLR369W 65 + GAACCCTCAACTGACTAAGA N|23|K silent|AAC>AAT|N|23 P|24|A P|24|S SSQ1 Stress-Seventy subfamily Q 657.0 0 0 0 0 0.524746027142504 Q05931 0.9111100435256958 0.7716965079307556 0.7472847700119019 44.57366069545482 45.0 1.0 no 9450 chrXII_859620r 25757 high_effect YLR369W 71 - TGACCTTCTTAGTCAGTTGA V|30|L V|30|I K|29|N silent|AAG>AAA|K|29 SSQ1 Stress-Seventy subfamily Q 657.0 0 0 0 0 -0.5337458811129178 Q05931 0.050832495093345635 0.507049560546875 0.22475463151931765 0.9697999954223632 48.56547398055636 40.0 1.0 no 9451 chrXII_859653r 25759 high_effect YLR369W 104 - CAGCACTATTCGTGGTACCC A|41|P A|41|T S|40|T S|40|N SSQ1 Stress-Seventy subfamily Q 657.0 0 0 0 0 -3.7064546956147617 Q05931 0.006959584075957537 0.013706506229937077 0.0 0.0 3.3919999599456787 1.5420000553131104 54.709456931346324 55.00000000000001 1.0 yes 9452 chrXII_859750r 25760 high_effect YLR369W 201 - ACATCAAAGGCAACTATAGA V|74|L V|74|I D|73|H D|73|N SSQ1 Stress-Seventy subfamily Q 657.0 0 0 0 0 0.004345823286624186 Q05931 0.1510060429573059 0.09315432608127594 0.002215625718235969 0.12457257509231567 -1.2075999975204468 -1.0736000537872314 38.83073657936143 35.0 1.0 no 9453 chrXII_859763r 25761 high_effect YLR369W 214 - TGGCGAGCTTTTGACATCAA silent|TCG>TCC|S|77 silent|TCG>TCA|S|77 SSQ1 Stress-Seventy subfamily Q 657.0 0 0 0 0 -0.3588682444706189 Q05931 47.66300598443326 45.0 1.0 no 9454 chrXII_859795 25762 high_effect YLR369W 243 + GATCAAATGAAAACTCTTGT Q|83|E Q|83|* SSQ1 Stress-Seventy subfamily Q 657.0 0 0 0 0 0.7592227084050245 Q05931 0.11880578845739365 34.891247784849675 30.0 1.0 no 9455 chrXII_859887r 25764 high_effect YLR369W 338 - CTTCCTTGTCGTTGAATGCA E|119|Q E|119|K K|118|N silent|AAG>AAA|K|118 SSQ1 Stress-Seventy subfamily Q 657.0 0 0 0 0 0.007900033250680059 Q05931 0.19144083559513086 0.2730589509010315 0.08212746679782867 50.33619296913293 45.0 1.0 no 9456 chrXII_859969 25766 high_effect YLR369W 417 + GCCTATCTCAGCACGTCTAA silent|GCC>GCG|A|140 silent|GCC>GCT|A|140 A|140|G A|140|V SSQ1 Stress-Seventy subfamily Q 657.0 0 0 0 0 -0.05555213831578162 Q05931 0.3525001108646393 0.3514905273914337 1.6729999780654907 0.7576000094413757 53.145993138168194 50.0 1.0 no 9457 chrXII_860198r 25774 high_effect YLR369W 649 - ATCATCAATTCCAAAGCTTA D|223|H D|223|N D|222|H D|222|N SSQ1 Stress-Seventy subfamily Q 657.0 0 0 0 0 0.289387441437972 Q05931 0.0039440421387553215 0.04247721284627914 0.02293620258569717 0.07060176879167558 -0.7003999948501587 -0.6421999931335449 41.00818905440485 30.0 1.0 no 9458 chrXII_860265 25775 high_effect YLR369W 713 + TACATTTGACATATCCATCT T|239|R T|239|I SSQ1 Stress-Seventy subfamily Q 657.0 0 0 0 0 -3.8717946965498777 Q05931 0.0 0.0 42.28333605100664 30.0 1.0 yes 9459 chrXII_860278 25776 high_effect YLR369W 726 + TCCATCTTGGACATTGAAGA silent|TCC>TCG|S|243 silent|TCC>TCT|S|243 S|243|C S|243|F SSQ1 Stress-Seventy subfamily Q 657.0 0 0 0 0 -0.3616014676277129 Q05931 0.0 0.0 44.99352686224125 40.0 1.0 no 9460 chrXII_860279r 25777 high_effect YLR369W 730 - GCCATCTTCAATGTCCAAGA G|250|R G|250|S G|250|A G|250|D SSQ1 Stress-Seventy subfamily Q 657.0 0 0 0 0 -0.6766991553277995 Q05931 0.02496941387653351 0.04531531035900116 0.004201084841042757 0.04399630054831505 50.20501569617363 45.0 1.0 no 9461 chrXII_860403r 25780 high_effect YLR369W 854 - TTTCTTCCCGTGTAATTTCA E|291|Q E|291|K E|290|Q E|290|K SSQ1 Stress-Seventy subfamily Q 657.0 0 0 0 0 0.6155578927321431 Q05931 0.002380376681685448 0.0029736454598605637 0.33553212881088257 1.0 48.50058864348239 35.0 1.0 no 9462 chrXII_860554r 25782 high_effect YLR369W 1005 - TCCAGCTCTTCCTCTGTCAT silent|CTG>CTC|L|341 silent|CTG>CTA|L|341 D|342|H D|342|N SSQ1 Stress-Seventy subfamily Q 657.0 0 0 0 0 1.5931759674845782 Q05931 0.00163292046636343 0.07310975342988968 59.533575836915645 50.0 1.0 no 9463 chrXII_860582 25783 high_effect YLR369W 1030 + TGACTTTGTCATTAATCAAC T|345|S T|345|I SSQ1 Stress-Seventy subfamily Q 657.0 0 0 0 0 1.2539067479986834 Q05931 0.5370870232582092 0.24644775688648224 37.429368006058674 30.0 1.0 no 9464 chrXII_860611r 25784 high_effect YLR369W 1062 - TTCAATGCTTGCTTCACAGG L|360|F silent|TTG>TTA|L|360 SSQ1 Stress-Seventy subfamily Q 657.0 0 0 0 0 -0.19848978311813734 Q05931 0.006305386312305927 -0.2946000099182129 48.311476389807865 45.0 1.0 no 9465 chrXII_860614r 25786 high_effect YLR369W 1065 - TCTTTCAATGCTTGCTTCAC D|362|H D|362|N L|360|F silent|TTG>TTA|L|360 SSQ1 Stress-Seventy subfamily Q 657.0 0 0 0 0 0.6246061010627146 Q05931 0.0017842735396698113 0.008338493295013905 0.006305386312305927 -0.2946000099182129 47.66391156428268 40.0 1.0 no 9466 chrXII_860710 25787 high_effect YLR369W 1158 + TCTGTTGTAAAAGATCTTTT S|387|C S|387|F SSQ1 Stress-Seventy subfamily Q 657.0 0 0 0 0 -0.1682362215092093 Q05931 0.009921715594828129 0.0093931769952178 36.901280671438656 25.0 1.0 no 9467 chrXII_860758 25788 high_effect YLR369W 1206 + CCAGATGAAACAGTTGCTTT P|403|R P|403|L SSQ1 Stress-Seventy subfamily Q 657.0 0 0 0 0 -1.4769580525537898 Q05931 0.0 0.0 44.40442394173937 40.0 1.0 no 9468 chrXII_860888r 25792 high_effect YLR369W 1339 - TGTCGTATTTCTAGGTATCA silent|ACG>ACC|T|452 silent|ACG>ACA|T|452 SSQ1 Stress-Seventy subfamily Q 657.0 0 0 0 0 -0.003432233240839827 Q05931 45.49523750050315 35.0 1.0 no 9469 chrXII_860896r 25793 high_effect YLR369W 1347 - ACTGGAACTGTCGTATTTCT V|456|L V|456|I SSQ1 Stress-Seventy subfamily Q 657.0 0 0 0 0 0.1727690643310883 Q05931 0.027233000844717026 0.09117917716503143 45.885092657299424 40.0 1.0 no 9470 chrXII_867364r 25796 high_effect YLR372W 13 - TGCTGCTATAACAGTAGATG A|11|P A|11|T A|10|P A|10|T ELO3 fatty acid ELOngation 345.0 0 0 0 0 -0.5424280454628952 P40319 0.9573720097541808 0.9523990154266356 0.9573720097541808 0.9523990154266356 42.54157514206861 40.0 1.0 no 9471 chrXII_867447 25798 high_effect YLR372W 93 + CCTTCCATTGAGAACCCATT P|32|R P|32|L S|33|C S|33|F ELO3 fatty acid ELOngation 345.0 0 0 0 0 -0.04645358346495665 P40319 0.9432820081710817 0.9430609941482544 0.945252001285553 0.9294660091400146 0.013101273216307163 0.01102372445166111 0.009715929627418518 0.005446732509881258 51.68681789639339 45.0 1.0 no 9472 chrXII_867700 25801 high_effect YLR372W 346 + CTTCTATTTCTCTAGTTTTA S|117|C S|117|F ELO3 fatty acid ELOngation 345.0 0 0 0 0 0.7005464722497838 P40319 0.945252001285553 0.9294660091400146 0.09377987682819366 0.1586536467075348 41.61244733447017 25.0 1.0 no 9473 chrXII_867744 25802 high_effect YLR372W 390 + GTTCCTATGGTTTATCACAA P|132|A P|132|S P|132|R P|132|L ELO3 fatty acid ELOngation 345.0 0 0 0 0 0.4608420281580963 P40319 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.0295198243111372 0.041280612349510186 0.06332369893789291 0.004748169332742691 45.54616426338953 35.0 1.0 no 9474 chrXII_867770 25804 high_effect YLR372W 416 + ATTCTGGTCTATCTGCTCTA F|140|L silent|TTC>TTT|F|140 ELO3 fatty acid ELOngation 345.0 0 0 0 0 0.7937246935325288 P40319 0.9387490153312684 0.1638130396604538 50.62258299225954 40.0 1.0 no 9475 chrXII_876107r 25807 essential YLR378C 1049 + GTCTTTATCCGAAGCTCTTC S|351|C S|351|F SEC61 SECretory 480.0 0 0 0 0 -0.035569536894312866 P32915 0.9634199738502502 0.9436050057411194 0.005191816482692957 0.00391065888106823 50.09169570939667 45.0 0.0 no 9476 chrXII_876208r 25813 essential YLR378C 948 + AATCCATTGATTCGTTTGAT P|318|A P|318|S P|318|R P|318|L SEC61 SECretory 480.0 0 0 0 0 0.397794135432721 P32915 0.9763929843902588 0.9679129719734192 0.95032000541687 0.9589239954948424 0.11246762424707413 0.059635281562805176 0.05548501387238503 1.0 42.09562901078829 30.0 0.0 no 9477 chrXII_876284 25816 essential YLR378C 875 - ATGCACTCTGCAACATGATT A|298|P A|298|T S|297|T S|297|N SEC61 SECretory 480.0 0 0 0 0 -1.3919140847041431 P32915 0.9863749742507936 0.9780830144882202 0.9762319922447203 0.98028302192688 0.0221437755972147 0.14406093955039978 0.328829288482666 0.123318113386631 45.88456479420853 40.0 0.0 no 9478 chrXII_876285 25817 essential YLR378C 874 - TGCACTCTGCAACATGATTG A|298|P A|298|T S|297|T S|297|N SEC61 SECretory 480.0 0 0 0 0 -0.04219315898779349 P32915 0.9863749742507936 0.9780830144882202 0.9762319922447203 0.98028302192688 0.0221437755972147 0.14406093955039978 0.328829288482666 0.123318113386631 45.88093962390798 45.0 0.0 no 9479 chrXII_876342 25819 essential YLR378C 817 - ACCAATTTGACCTCTCACTT G|279|R G|279|S G|279|A G|279|D SEC61 SECretory 480.0 0 0 0 0 -0.4405054607651338 P32915 0.9477360248565674 0.9668909907341005 0.9656509757041932 0.9535760283470154 0.1663132905960083 0.4135090410709381 0.3294413983821869 0.1132519468665123 48.68175599437092 40.0 0.0 no 9480 chrXII_876354 25820 essential YLR378C 805 - TCTCACTTTGGTTGACCTGA silent|GTG>GTC|V|274 silent|GTG>GTA|V|274 R|275|T R|275|K SEC61 SECretory 480.0 0 0 0 0 -0.026024036152691776 P32915 0.9657250046730042 0.9840949773788452 0.005534880328923464 0.16375665366649628 -0.3138000071048737 -0.10859999805688858 51.082478930033226 45.0 0.0 no 9481 chrXII_876355 25822 essential YLR378C 804 - CTCACTTTGGTTGACCTGAT silent|GTG>GTC|V|274 silent|GTG>GTA|V|274 V|274|L V|274|M SEC61 SECretory 480.0 0 0 0 0 -1.5205444940337378 P32915 0.9786369800567628 0.9877660274505616 0.6412015557289124 0.22525380551815036 0.0843999981880188 -1.236199975013733 49.93316726104149 45.0 0.0 no 9482 chrXII_876369r 25825 essential YLR378C 787 + TCCGTTACGAATTGCCCATC R|264|G R|264|C F|263|L silent|TTC>TTT|F|263 SEC61 SECretory 480.0 0 0 0 0 -0.7932740898970485 P32915 0.9377340078353882 0.9377790093421936 0.9660270214080809 0.003199222730472684 0.00042404758278280497 0.26968154311180115 -0.1842000037431717 0.975600004196167 0.5401999950408936 1.0429999828338623 52.049071698727005 50.0 0.0 no 9483 chrXII_876433 25828 essential YLR378C 726 - ATCAACACTTGGAACATATT L|248|F silent|TTG>TTA|L|248 silent|GTG>GTC|V|247 silent|GTG>GTA|V|247 SEC61 SECretory 480.0 0 0 0 0 -1.2326499633177217 P32915 0.9798439741134644 0.1962425112724304 0.16580000519752502 38.1130195675168 30.0 0.0 no 9484 chrXII_876543 25833 essential YLR378C 616 - TTCGAACTCCTTACCACGAC E|212|Q E|212|K E|210|D silent|GAG>GAA|E|210 SEC61 SECretory 480.0 0 0 0 0 0.15798089678656296 P32915 0.9202449917793274 0.9081959724426271 0.912388026714325 0.03466842323541641 0.013349083252251148 0.01463825162500143 0.2360000014305115 0.11779999732971193 48.57082352448987 50.0 0.0 no 9485 chrXII_876647r 25837 essential YLR378C 509 + GCTATCTAAGGGTTACGGCT L|171|V silent|CTA>TTA|L|171 S|172|C S|172|F SEC61 SECretory 480.0 0 0 0 0 0.20816657356059146 P32915 0.9148989915847778 0.971517026424408 0.9521960020065308 0.059140440076589584 0.003042871132493019 0.0026881592348217964 -0.184799998998642 51.60261231881975 50.0 0.0 no 9486 chrXII_876796r 25844 essential YLR378C 360 + TGCGCTATTATTCTGATCTT C|121|W silent|TGC>TGT|C|121 A|122|G A|122|V SEC61 SECretory 480.0 0 0 0 0 0.13153095804133835 P32915 0.941407024860382 0.9764879941940308 0.9757149815559388 0.007254426833242178 1.0 0.11350905895233156 -1.5604000091552734 1.1601999998092651 -0.8098000288009644 46.07701090919153 35.0 0.0 no 9487 chrXII_876797r 25845 essential YLR378C 359 + GTGCGCTATTATTCTGATCT C|121|W silent|TGC>TGT|C|121 A|122|G A|122|V SEC61 SECretory 480.0 0 0 0 0 0.19093926695140712 P32915 0.941407024860382 0.9764879941940308 0.9757149815559388 0.007254426833242178 1.0 0.11350905895233156 -1.5604000091552734 1.1601999998092651 -0.8098000288009644 48.458054036751086 40.0 0.0 no 9488 chrXII_876815 25846 essential YLR378C 344 - CGCACACCTTTTGAGCAATT C|121|S C|121|Y silent|GTG>GTC|V|120 silent|GTG>GTA|V|120 SEC61 SECretory 480.0 0 0 0 0 0.9988081806800236 P32915 0.9601609706878662 0.9424200057983398 0.01407730020582676 0.01322911772876978 0.015599999576807022 -1.1252000331878662 48.756205708609905 45.0 0.0 no 9489 chrXII_876821r 25847 essential YLR378C 335 + GCTGTTCCAAATTGCTCAAA L|113|V silent|CTG>TTG|L|113 F|114|L silent|TTC>TTT|F|114 SEC61 SECretory 480.0 0 0 0 0 -0.08093837401751224 P32915 0.9141610264778136 0.9584370255470276 0.045710086822509766 0.39928168058395386 1.3372000455856323 -0.2750000059604645 45.4957215847981 40.0 0.0 no 9490 chrXII_876844 25849 essential YLR378C 315 - TCTCTGTCCTGCTTGCTCTC R|111|T R|111|K E|112|Q E|112|K SEC61 SECretory 480.0 0 0 0 0 0.7631044699156866 P32915 0.9640290141105652 0.9823979735374452 0.9857460260391236 0.9736970067024232 0.011295025236904621 0.18746913969516754 0.551444411277771 0.7717776298522949 60.92373590445954 55.00000000000001 0.0 no 9491 chrXII_876906 25850 essential YLR378C 253 - AATCATAGATGAAGTGATGA M|90|I M|90|I SEC61 SECretory 480.0 0 0 0 0 -0.9827216077584164 P32915 0.9849619865417479 0.9849619865417479 0.04679006338119507 0.04679006338119507 35.508321369433304 30.0 0.0 no 9492 chrXII_876938 25851 essential YLR378C 221 - CCAATTCCAGTAAAGTACCA L|80|F silent|TTG>TTA|L|80 E|79|Q E|79|K SEC61 SECretory 480.0 0 0 0 0 -2.0052045656578965 P32915 0.9341800212860109 0.9209830164909364 0.9089339971542358 0.05618222430348396 0.007604742888361216 0.005871120374649763 45.80005832006197 40.0 0.0 no 9493 chrXII_876938r 25852 essential YLR378C 218 + CCGTGGTACTTTACTGGAAT R|74|G R|74|C SEC61 SECretory 480.0 0 0 0 0 -0.11881460172617453 P32915 0.8739299774169922 0.8739749789237976 0.0023802719078958035 0.0003204491222277284 47.652017825948114 45.0 0.0 no 9494 chrXII_876974 25856 essential YLR378C 185 - TGGCACGTAGCCAGTACAGA A|68|P A|68|T R|67|P R|67|H SEC61 SECretory 480.0 0 0 0 0 -1.3035037549076924 P32915 0.9863749742507936 0.9780830144882202 0.960108995437622 1.0001100301742554 0.09825486689805983 0.18085353076457975 0.0 0.0 -0.4277999997138977 2.0109999179840092 54.238536848865245 55.00000000000001 0.0 no 9495 chrXII_876984r 25857 essential YLR378C 172 + AGACTTCCGACCCTCTGTAC T|59|S T|59|I S|60|C S|60|F SEC61 SECretory 480.0 0 0 0 0 0.331929898126959 P32915 0.9758769869804382 0.9739249944686891 0.9720100164413452 0.9521960020065308 1.0 0.020172307267785072 0.09291993826627733 0.0726199597120285 55.326931034839326 55.00000000000001 0.0 no 9496 chrXII_885318r 25862 essential YLR383W 33 - TCATCATCAACCTGCTCTAT E|18|Q E|18|K D|17|H D|17|N SMC6 Structural Maintenance of Chromosomes 1114.0 0 0 0 0 0.40240243850764507 Q12749 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.18724896013736725 0.20550687611103055 0.09819024056196213 1.0 48.48324465976333 40.0 1.0 no 9497 chrXII_885344 25863 essential YLR383W 56 + ACTTTCACTGACTGCGCAGC L|20|V L|20|F S|21|* S|21|L SMC6 Structural Maintenance of Chromosomes 1114.0 0 0 0 0 0.4722490745383687 Q12749 0.9512209892272948 0.9587849974632264 0.9298099875450134 0.269027441740036 0.14100101590156555 0.1617886871099472 53.69367513416717 55.00000000000001 1.0 no 9498 chrXII_885467 25867 essential YLR383W 179 + GAGCTCCTCTGACGTGGCCA S|61|R silent|AGC>AGT|S|61 S|62|C S|62|F SMC6 Structural Maintenance of Chromosomes 1114.0 0 0 0 0 -0.6166572162521937 Q12749 0.9417110085487366 0.945252001285553 0.9294660091400146 0.39289167523384094 0.0901837721467018 0.1036161556839943 62.087639359670845 65.0 1.0 no 9499 chrXII_885519r 25868 essential YLR383W 234 - ACTTTCTTAATATATCCTGA V|85|L V|85|M K|83|N silent|AAG>AAA|K|83 SMC6 Structural Maintenance of Chromosomes 1114.0 0 0 0 0 -0.31978723865543435 Q12749 0.9539830088615416 0.9587630033493042 0.9355990290641784 0.2355792969465256 0.016368493437767032 0.013699274510145187 39.69405258965833 25.0 1.0 no 9500 chrXII_885567 25869 essential YLR383W 279 + GAACATTTTGAACTTGAGCT H|95|D H|95|Y SMC6 Structural Maintenance of Chromosomes 1114.0 0 1 0 0 0.7756370842329974 Q12749 0.9473130106925964 0.9489949941635132 0.20337334275245667 0.030911803245544437 40.497500722711436 35.0 1.0 no 9501 chrXII_885645 25870 essential YLR383W 357 + ACCGCCATTACTATTGGTTT silent|ACC>ACG|T|120 silent|ACC>ACT|T|120 T|120|S T|120|I SMC6 Structural Maintenance of Chromosomes 1114.0 0 0 0 0 -0.3700461647027938 Q12749 0.9491789937019348 0.9472420215606691 0.0 0.0 50.449033058870384 40.0 1.0 no 9502 chrXII_885670r 25872 essential YLR383W 385 - TCTGTTAGTCTCGCTAGCCT R|135|T R|135|K SMC6 Structural Maintenance of Chromosomes 1114.0 0 0 0 0 -0.4622624712356015 Q12749 0.932735025882721 0.955805003643036 0.0 0.0 57.18281634689368 50.0 1.0 no 9503 chrXII_885686 25873 essential YLR383W 398 + TAACAGAGGTTCCTCTTTGA N|134|K silent|AAC>AAT|N|134 SMC6 Structural Maintenance of Chromosomes 1114.0 0 0 0 0 0.437139694260741 Q12749 0.9439849853515624 0.02116414718329906 46.683348693177436 40.0 1.0 no 9504 chrXII_885734 25874 essential YLR383W 446 + TGCTAAAATCATCCTTCATC A|150|G A|150|V SMC6 Structural Maintenance of Chromosomes 1114.0 0 0 0 0 0.15651855177623414 Q12749 0.9484469890594482 0.9504740238189696 0.09813037514686583 0.03452621027827263 42.10010367087187 35.0 1.0 no 9505 chrXII_885746r 25875 essential YLR383W 461 - ACTTGCTATTATCCAGATGA K|160|N silent|AAG>AAA|K|160 S|159|T S|159|N SMC6 Structural Maintenance of Chromosomes 1114.0 0 0 0 0 0.6386916790760635 Q12749 0.9355990290641784 0.9512869715690612 0.9536849856376648 0.2621890604496002 0.347249835729599 0.7336705327033997 44.98340420652687 35.0 1.0 no 9506 chrXII_885774 25876 essential YLR383W 486 + GCTTATCAGCAAGGTATTTT A|163|G A|163|V Q|165|E Q|165|* SMC6 Structural Maintenance of Chromosomes 1114.0 0 0 0 0 -0.2559353487844561 Q12749 0.9484469890594482 0.9504740238189696 0.9590039849281312 0.4444565773010254 0.0592203140258789 1.0 45.453014420799825 35.0 1.0 no 9507 chrXII_885839 25878 essential YLR383W 551 + CGCTTCTTTTAGTTTAAGGT A|185|G A|185|V S|186|C S|186|F SMC6 Structural Maintenance of Chromosomes 1114.0 0 0 0 0 -0.6574897167153755 Q12749 0.9484469890594482 0.9504740238189696 0.945252001285553 0.9294660091400146 0.2537515461444855 0.08722351491451262 0.03616785258054733 0.01967143639922142 45.26205941973125 35.0 1.0 no 9508 chrXII_885950r 25881 essential YLR383W 665 - ACCTAGCAGCGTCTTGTGAC R|228|T R|228|K R|228|S silent|AGG>AGA|R|228 SMC6 Structural Maintenance of Chromosomes 1114.0 0 0 0 0 -1.5563524476473036 Q12749 0.932735025882721 0.955805003643036 0.9087679982185364 0.01491431426256895 0.22462277114391327 0.011975123547017573 54.879499009110525 55.00000000000001 1.0 no 9509 chrXII_886900r 25890 essential YLR383W 1615 - ACCTTTTCTAATTGTTACAA G|545|R G|545|S G|545|A G|545|D SMC6 Structural Maintenance of Chromosomes 1114.0 0 0 0 0 0.4880654917419687 Q12749 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.052051644772291183 0.16015936434268951 0.07516518235206604 0.40788498520851135 39.63786896977166 25.0 1.0 no 9510 chrXII_887053r 25893 essential YLR383W 1768 - ACTCAAGCAATAAGTAACAA L|595|F silent|TTG>TTA|L|595 S|596|T S|596|N SMC6 Structural Maintenance of Chromosomes 1114.0 0 0 0 0 0.15293914516987314 Q12749 0.9587849974632264 0.9512869715690612 0.9536849856376648 0.4104292392730713 0.6322817206382751 0.668410062789917 35.157874509790474 30.0 1.0 no 9511 chrXII_887073 25894 essential YLR383W 1785 + AGTCAATTTGATTATTCGAA Q|597|E Q|597|* SMC6 Structural Maintenance of Chromosomes 1114.0 0 0 0 0 0.5674499348002052 Q12749 0.9590039849281312 1.0 36.39382155464836 25.0 1.0 no 9512 chrXII_887115r 25895 essential YLR383W 1830 - TCTAGTGCATCCACAATAGT E|617|Q E|617|K SMC6 Structural Maintenance of Chromosomes 1114.0 0 0 0 0 -0.03164166133510085 Q12749 0.956179976463318 0.9475290179252625 0.11018937081098557 0.10131307691335678 47.54365470569979 40.0 1.0 no 9513 chrXII_887148r 25896 essential YLR383W 1863 - ACGAATAAGCATTCAATTTC V|628|L V|628|I SMC6 Structural Maintenance of Chromosomes 1114.0 0 0 0 0 0.439447747962558 Q12749 0.9539830088615416 0.9574310183525084 0.18905676901340485 0.275024950504303 36.607927306628426 30.0 1.0 no 9514 chrXII_887355 25901 essential YLR383W 2067 + GTCAACTCTTCATCCGACAA silent|GTC>GTG|V|690 silent|GTC>GTT|V|690 N|691|K silent|AAC>AAT|N|691 SMC6 Structural Maintenance of Chromosomes 1114.0 0 0 0 0 0.24352157140214936 Q12749 0.9439849853515624 0.5907869338989258 47.565793946998504 45.0 1.0 no 9515 chrXII_887356 25902 essential YLR383W 2068 + TCAACTCTTCATCCGACAAT silent|GTC>GTG|V|690 silent|GTC>GTT|V|690 N|691|K silent|AAC>AAT|N|691 SMC6 Structural Maintenance of Chromosomes 1114.0 0 0 0 0 1.1252230792691589 Q12749 0.9439849853515624 0.5907869338989258 45.09703611336113 40.0 1.0 no 9516 chrXII_887438r 25903 essential YLR383W 2153 - CACTTAGCTTTTCCTCGTAA S|724|T S|724|N SMC6 Structural Maintenance of Chromosomes 1114.0 0 0 0 0 0.19870698763606032 Q12749 0.9512869715690612 0.9536849856376648 0.5514234900474548 0.5459297299385071 48.1488178943049 40.0 1.0 no 9517 chrXII_887541 25904 essential YLR383W 2253 + ACAGAATTAAAAATGAATGT T|752|R T|752|I SMC6 Structural Maintenance of Chromosomes 1114.0 0 0 0 0 -0.4679568217008282 Q12749 0.9476869702339172 0.9472420215606691 0.44465142488479614 0.15426507592201233 28.652484642905048 20.0 1.0 no 9518 chrXII_887644r 25908 essential YLR383W 2359 - CAGCCCTAATTCTTCTTTAG silent|GGG>GGC|G|792 silent|GGG>GGA|G|792 G|792|A G|792|E SMC6 Structural Maintenance of Chromosomes 1114.0 0 0 0 0 -0.4625013858951577 Q12749 0.9499930143356324 0.9438679814338684 0.7351878881454468 1.0 47.88390211092946 40.0 1.0 no 9519 chrXII_903200 25911 no_effect YLR390W 134 + ATGCCTTGTGGGAGTCTACA C|46|W silent|TGC>TGT|C|46 L|47|V L|47|F ECM19 ExtraCellular Mutant 112.0 0 0 0 0 -0.4943479480748946 Q06011 0.9286419749259948 0.9512209892272948 0.9587849974632264 54.433031465290874 50.0 1.0 no 9520 chrXII_903291r 25913 no_effect YLR390W 228 - TCCTCGTCGTATTCTGGGAT E|82|D silent|GAG>GAA|E|82 D|83|H D|83|N ECM19 ExtraCellular Mutant 112.0 0 0 0 0 -0.9272227864027204 Q06011 0.94931298494339 0.9486550092697144 0.956179976463318 53.99266148175497 50.0 1.0 no 9521 chrXII_903297r 25914 no_effect YLR390W 234 - TTTCCGTCCTCGTCGTATTC G|84|A G|84|E G|84|R G|84|R ECM19 ExtraCellular Mutant 112.0 0 0 0 0 -0.2112722220558977 Q06011 0.9499930143356324 0.9438679814338684 0.941340982913971 0.941340982913971 55.181625600054424 50.0 1.0 no 9522 chrXII_913145r 25916 essential YLR397C 1725 + ATCAACTTCTTAGCTGTGAA I|576|M silent|ATC>ATT|I|576 N|577|K silent|AAC>AAT|N|577 AFG2 ATPase Family Gene 780.0 0 0 0 0 0.04276897862951487 P32794 1.0187599658966064 0.8048949837684631 0.06536822766065598 0.0 -0.5052000284194946 42.72132554307041 35.0 0.0 no 9523 chrXII_913174 25917 essential YLR397C 1699 - TTCTGTAGCGAGAGCTTTTG E|573|Q E|573|K AFG2 ATPase Family Gene 780.0 0 0 0 0 -0.7593267781616206 P32794 0.9293829798698424 0.920324981212616 0.0 0.0 48.17194733846799 45.0 0.0 no 9524 chrXII_913223r 25919 essential YLR397C 1647 + CCAAAAGGTGTATTACTTTA P|550|R P|550|L AFG2 ATPase Family Gene 780.0 0 0 0 0 -2.4948786000930907 P32794 0.8374800086021423 0.8180059790611267 0.006489128340035677 0.00889771431684494 38.92143022640784 30.0 0.0 yes 9525 chrXII_913256r 25920 essential YLR397C 1614 + TCGGAGACTTTTGCCAGGCT S|539|W S|539|L AFG2 ATPase Family Gene 780.0 0 0 0 0 0.462718796399182 P32794 0.8218370079994202 0.9382860064506532 0.017531540244817734 0.13895779848098755 56.11286854654793 55.00000000000001 0.0 no 9526 chrXII_913261r 25922 essential YLR397C 1609 + AGGCTTCGGAGACTTTTGCC A|538|G A|538|V S|539|W S|539|L AFG2 ATPase Family Gene 780.0 0 0 0 0 -0.6796884178519367 P32794 0.9318490028381348 0.9106420278549194 0.8218370079994202 0.9382860064506532 0.5258350372314453 0.3757459223270416 0.017531540244817734 0.13895779848098755 -0.8863999843597412 1.6224000453948977 55.19622764347634 55.00000000000001 0.0 no 9527 chrXII_913422 25925 essential YLR397C 1451 - CATCTTTCAATGTAACTTTT D|490|H D|490|N AFG2 ATPase Family Gene 780.0 0 0 0 0 0.8792902357940704 P32794 0.7834849953651428 0.8298500180244446 0.07395575940608977 0.06011705845594406 38.07262461403684 25.0 0.0 no 9528 chrXII_913423 25926 essential YLR397C 1450 - ATCTTTCAATGTAACTTTTA D|490|H D|490|N L|488|F silent|TTG>TTA|L|488 AFG2 ATPase Family Gene 780.0 0 0 0 0 0.11443959972472699 P32794 0.7834849953651428 0.8298500180244446 1.0456199645996094 0.07395575940608977 0.06011705845594406 0.7467470169067383 -1.1990000009536743 36.10896550486831 20.0 0.0 no 9529 chrXII_913541r 25927 essential YLR397C 1329 + TACATTGCTTCTAAAACGCA Y|444|* silent|TAC>TAT|Y|444 AFG2 ATPase Family Gene 780.0 0 0 0 0 0.4509205116806728 P32794 41.04509927855935 35.0 0.0 no 9530 chrXII_913579 25928 essential YLR397C 1294 - ATCTAATACGTGACGATCCG D|438|H D|438|N AFG2 ATPase Family Gene 780.0 0 0 0 0 -0.3552181500199649 P32794 0.8383460044860841 0.9428920149803162 0.06578026711940765 0.3965625762939453 43.8258574749874 45.0 0.0 no 9531 chrXII_913631 25930 essential YLR397C 1242 - TCAAATCTGGCATCAACGTC D|421|H D|421|N R|419|T R|419|K AFG2 ATPase Family Gene 780.0 0 0 0 0 0.4789422757830642 P32794 0.9550390243530272 0.9716100096702576 0.5702970027923584 0.6072379946708679 0.015352486632764341 0.03876350447535515 0.0 0.0 44.59004408120205 45.0 0.0 no 9532 chrXII_913667 25931 essential YLR397C 1206 - ACTTCTTGGTCAAACCTGCC V|409|L V|409|I E|408|Q E|408|K AFG2 ATPase Family Gene 780.0 0 0 0 0 -1.614496057582078 P32794 0.916023015975952 0.957198977470398 0.7501329779624939 0.8128100037574768 0.21647705137729645 1.0 0.0 0.0 52.48260323885757 50.0 0.0 no 9533 chrXII_913756 25934 essential YLR397C 1117 - AGCGCCCATGCCATCCATTA A|379|P A|379|T G|378|A G|378|D AFG2 ATPase Family Gene 780.0 0 0 0 0 0.30744566957679603 P32794 1.0359699726104736 1.0467000007629397 1.1005799770355225 1.098140001296997 0.22862063348293304 0.6141274571418762 0.7459617853164673 0.7566486597061157 5.594200134277344 1.0047999620437622 60.24128988399497 55.00000000000001 0.0 no 9534 chrXII_913770r 25935 essential YLR397C 1100 + GGCTACATTGCTTACCCTAA A|368|G A|368|V T|369|R T|369|I AFG2 ATPase Family Gene 780.0 0 0 0 0 -0.0912584191941552 P32794 0.9273380041122437 0.8336189985275269 0.8524519801139832 0.8593549728393555 0.11307862401008605 0.035881660878658295 0.0046901004388928405 0.005178789608180523 0.9950000047683716 -0.08860000222921371 51.40349262470551 45.0 0.0 no 9535 chrXII_913766r 25936 essential YLR397C 1104 + ACATTGCTTACCCTAATGGA T|369|R T|369|I L|371|V L|371|F AFG2 ATPase Family Gene 780.0 0 0 0 0 -1.9454580293136936 P32794 0.8524519801139832 0.8593549728393555 0.8179969787597656 0.7051219940185547 0.0046901004388928405 0.005178789608180523 0.1443818062543869 0.0711514875292778 2.0025999546051025 0.9488000273704528 47.739914817220274 40.0 0.0 no 9536 chrXII_913761r 25937 essential YLR397C 1109 + GCTTACCCTAATGGATGGCA L|371|V L|371|F T|372|S T|372|I AFG2 ATPase Family Gene 780.0 0 0 0 0 -1.0913353002880506 P32794 0.8179969787597656 0.7051219940185547 0.8747940063476562 0.8102009892463684 0.1443818062543869 0.0711514875292778 0.257368803024292 0.01668444089591503 2.0025999546051025 0.9488000273704528 52.884865229895134 50.0 0.0 no 9537 chrXII_913795 25938 essential YLR397C 1078 - GACTCTGCTCTCAACTTCAC V|366|L V|366|I R|365|T R|365|K AFG2 ATPase Family Gene 780.0 0 0 0 0 -0.7981093314032185 P32794 0.9609349966049194 1.0018500089645386 0.776993989944458 0.8832889795303345 0.34121906757354736 0.479051798582077 0.012070959433913231 0.07286173105239868 -1.4013999700546265 -1.4104000329971311 50.14883247529286 50.0 0.0 no 9538 chrXII_913931r 25939 essential YLR397C 939 + TCAATCGTCTCCAAATATCT S|314|* S|314|L I|315|M silent|ATC>ATT|I|315 AFG2 ATPase Family Gene 780.0 0 0 0 0 0.5875252019350293 P32794 0.8392350077629089 0.6756200194358826 0.0 0.007402667775750159 -1.3007999658584597 42.935891601888606 35.0 0.0 no 9539 chrXII_914010 25943 essential YLR397C 863 - GCATAGTTTTACCAGTACCT M|294|I M|294|I AFG2 ATPase Family Gene 780.0 0 0 0 0 0.16273013010254428 P32794 0.9258909821510316 0.9258909821510316 0.07170122116804123 0.07170122116804123 0.8309999704360962 0.8309999704360962 50.424478209452104 40.0 0.0 no 9540 chrXII_914069 25945 essential YLR397C 804 - CCAAAGCTACTAAATAGCGT G|275|R G|275|S S|273|T S|273|N AFG2 ATPase Family Gene 780.0 0 0 0 0 0.21294791599230786 P32794 0.8198480010032654 0.918857991695404 1.048359990119934 1.0533299446105957 0.02932892926037312 0.08942868560552597 0.6450076103210449 0.5460177063941956 0.20720000565052032 0.3382000029087067 42.14987307160044 40.0 0.0 no 9541 chrXII_914069r 25946 essential YLR397C 801 + CCGACGCTATTTAGTAGCTT P|268|R P|268|L T|269|R T|269|M AFG2 ATPase Family Gene 780.0 0 0 0 0 0.15352004686337495 P32794 0.8782749772071838 0.8629999756813049 1.0033600330352783 0.9742100238800048 0.02049051597714424 0.026116108521819115 0.08370672911405562 0.01963282749056816 49.74190994522571 45.0 0.0 no 9542 chrXII_914199r 25951 essential YLR397C 671 + AACTTTTTCGAAAGAAACCC T|225|S T|225|I AFG2 ATPase Family Gene 780.0 0 0 0 0 0.09157292288652047 P32794 1.0083999633789062 1.0077199935913086 0.7429953217506409 0.19493381679058075 38.666323096186545 35.0 0.0 no 9543 chrXII_914209 25952 essential YLR397C 664 - TTTCGAAAAAGTTATATGTG silent|TCG>TCC|S|227 silent|TCG>TCA|S|227 AFG2 ATPase Family Gene 780.0 0 0 0 0 -0.4971987984944389 P32794 32.24537947876911 25.0 0.0 no 9544 chrXII_914295 25954 essential YLR397C 578 - CGTCCATGTTAAGATCTAGT D|199|H D|199|N M|198|I M|198|I AFG2 ATPase Family Gene 780.0 0 0 0 0 -0.4776525819129575 P32794 0.8693839907646179 1.0163199901580808 1.0360300540924072 1.0360300540924072 0.12289657443761826 0.4960514008998871 0.4707616865634918 0.4707616865634918 45.95310231251892 40.0 0.0 no 9545 chrXII_914298r 25955 essential YLR397C 572 + CAGCCAACTAGATCTTAACA S|192|R silent|AGC>AGT|S|192 Q|193|E Q|193|* AFG2 ATPase Family Gene 780.0 0 0 0 0 -0.3631805325157211 P32794 1.0188699960708618 1.0610699653625488 0.0358336977660656 1.0 43.646886507959785 40.0 0.0 no 9546 chrXII_914575 25960 essential YLR397C 298 - CCCAACAGATCGTATAGTTG G|106|R G|106|R G|106|A G|106|E AFG2 ATPase Family Gene 780.0 0 0 0 0 -0.4647942311905797 P32794 0.8926259875297546 0.8926259875297546 1.0564299821853638 0.9260200262069702 0.340522825717926 0.340522825717926 0.586251437664032 0.27157267928123474 46.13681288749365 45.0 0.0 no 9547 chrXII_914576r 25962 essential YLR397C 294 + TCCACAACTATACGATCTGT silent|TCC>TCG|S|99 silent|TCC>TCT|S|99 S|99|C S|99|F AFG2 ATPase Family Gene 780.0 0 0 0 0 0.4306853293003117 P32794 0.8914070129394531 0.8896859884262085 0.026398804038763046 0.015395278111100197 44.95145136074058 40.0 0.0 no 9548 chrXII_914696r 25965 essential YLR397C 174 + TCCTCGCTTGAGATAAATCC silent|TCC>TCG|S|59 silent|TCC>TCT|S|59 S|59|C S|59|F AFG2 ATPase Family Gene 780.0 0 0 0 0 -1.3640831787011076 P32794 0.8921610116958618 0.924498975276947 0.032003533095121384 0.030145736411213875 47.37923241598219 45.0 0.0 no 9549 chrXII_914794 25969 essential YLR397C 79 - TTCAGCAGGCAATTTAAATT E|33|Q E|33|K A|32|P A|32|T AFG2 ATPase Family Gene 780.0 0 0 0 0 0.04953991698506592 P32794 0.9887580275535583 1.0132499933242798 0.9735400080680848 1.022439956665039 0.4883710741996765 0.8615396022796631 0.2820652723312378 0.5890467762947083 40.02669001332253 30.0 0.0 no 9550 chrXII_920200 25976 high_effect YLR399C 1377 - TCTTCCAAATACTGGATGGC E|466|Q E|466|K E|465|Q E|465|K BDF1 BromoDomain Factor 686.0 0 0 0 0 -0.07300499381505354 P35817 1.0004899501800537 0.9891330003738404 1.0002599954605105 0.9889079928398132 0.5311408638954163 0.6422915458679199 0.09912670403718947 0.09963178634643556 46.68596987477372 45.0 0.0 no 9551 chrXII_920378r 25978 high_effect YLR399C 1196 + TGGCACGATCGTTAATATGA silent|GGC>GGG|G|400 silent|GGC>GGT|G|400 T|401|R T|401|M BDF1 BromoDomain Factor 686.0 0 0 0 1 -0.26781016811377417 P35817 0.9773380160331726 0.9916599988937378 0.006857392378151417 0.0038814912550151352 43.13829769799696 40.0 0.0 no 9552 chrXII_920398r 25979 high_effect YLR399C 1176 + TGCTACACGTTCAATCCGGA C|393|W silent|TGC>TGT|C|393 Y|394|* silent|TAC>TAT|Y|394 BDF1 BromoDomain Factor 686.0 0 0 0 0 0.6593145787003029 P35817 0.9663929939270021 0.0 50.387440738105234 50.0 0.0 no 9553 chrXII_920402r 25980 high_effect YLR399C 1172 + AAACTGCTACACGTTCAATC N|392|K silent|AAC>AAT|N|392 C|393|W silent|TGC>TGT|C|393 BDF1 BromoDomain Factor 686.0 0 0 0 0 -0.5688377380490158 P35817 0.9907550215721129 0.9663929939270021 0.01293595414608717 0.0 41.51046082997789 40.0 0.0 no 9554 chrXII_920472 25981 high_effect YLR399C 1105 - CTGCCAGTCATTTAATTTCT W|374|C W|374|* W|374|S W|374|* BDF1 BromoDomain Factor 686.0 0 0 0 0 0.2353129722361572 P35817 0.9440850019454956 0.9438130259513856 0.05867031216621399 0.5522044897079468 46.547323639844144 35.0 0.0 no 9555 chrXII_920475r 25982 high_effect YLR399C 1099 + TCGCCAAGAAATTAAATGAC A|368|G A|368|V I|367|M silent|ATC>ATT|I|367 BDF1 BromoDomain Factor 686.0 0 0 0 0 -2.1902852210254844 P35817 0.9919250011444092 0.991150975227356 0.9338020086288452 0.5275177955627441 0.16460810601711273 0.09357531368732452 36.50517800540706 35.0 0.0 yes 9556 chrXII_920548 25986 high_effect YLR399C 1029 - TTCATAGAAACTGGGTCTAC M|349|I M|349|I BDF1 BromoDomain Factor 686.0 0 0 0 0 0.2356769791824279 P35817 0.999705970287323 0.999705970287323 0.09086117148399353 0.09086117148399353 41.67671517877965 40.0 0.0 no 9557 chrXII_920573r 25987 high_effect YLR399C 1001 + CTCTTATAACTACCCATTTT S|335|C S|335|F BDF1 BromoDomain Factor 686.0 0 0 0 0 0.09481548328702304 P35817 0.9879119992256165 0.9685909748077391 0.027162125334143642 0.015801260247826576 43.44356579010377 30.0 0.0 no 9558 chrXII_920668 25988 high_effect YLR399C 909 - TTCGGTTTCTTCGATTCATA silent|CCG>CCC|P|309 silent|CCG>CCA|P|309 BDF1 BromoDomain Factor 686.0 0 0 0 0 0.40119866983550345 P35817 45.64702469385333 35.0 0.0 no 9559 chrXII_920729 25990 high_effect YLR399C 848 - TCGGCCTCCCATTATGAGTT silent|CCG>CCC|P|289 silent|CCG>CCA|P|289 R|288|S silent|AGG>AGA|R|288 BDF1 BromoDomain Factor 686.0 0 0 0 0 0.18497889403305007 P35817 0.9618290066719056 0.11878202855587006 56.6465709676192 50.0 0.0 no 9560 chrXII_920736r 25993 high_effect YLR399C 838 + GACGAGCCCAAACTCATAAT R|281|G R|281|* A|282|G A|282|V BDF1 BromoDomain Factor 686.0 0 0 0 0 0.7125723808281115 P35817 0.9520599842071532 0.9117249846458436 0.9109519720077516 0.3544309139251709 0.3964446187019348 0.29892927408218384 45.37110133726014 45.0 0.0 no 9561 chrXII_920737r 25994 high_effect YLR399C 837 + AGACGAGCCCAAACTCATAA R|281|G R|281|* BDF1 BromoDomain Factor 686.0 0 0 0 0 -0.09054650436418776 P35817 0.9520599842071532 0.3544309139251709 45.43768867627232 45.0 0.0 no 9562 chrXII_920762 25997 high_effect YLR399C 815 - TTACAATTGGGGCATCCTCT V|278|L V|278|I BDF1 BromoDomain Factor 686.0 0 0 0 0 -0.7195505955903337 P35817 0.9138749837875366 0.9215430021286012 0.6085067987442017 0.37391820549964905 51.017459819387796 45.0 0.0 no 9563 chrXII_920763 25998 high_effect YLR399C 814 - TACAATTGGGGCATCCTCTT V|278|L V|278|I BDF1 BromoDomain Factor 686.0 0 0 0 0 -0.9101992690570488 P35817 0.9138749837875366 0.9215430021286012 0.6085067987442017 0.37391820549964905 51.01745981938785 45.0 0.0 no 9564 chrXII_920800r 26002 high_effect YLR399C 774 + GCTCCACCTGTAATAGCCAA P|260|A P|260|S A|259|G A|259|V BDF1 BromoDomain Factor 686.0 0 0 0 0 -0.3553127954349736 P35817 0.9314339756965636 0.9229540228843688 0.922241985797882 0.92146897315979 0.035631213337183 0.04098157212138176 0.2594622373580933 0.29594290256500244 53.777447093499525 50.0 0.0 no 9565 chrXII_920995 26003 high_effect YLR399C 582 - TCTATAGTAGACAAGTCCAT E|201|Q E|201|K BDF1 BromoDomain Factor 686.0 0 0 0 0 0.4166803875135524 P35817 1.0004899501800537 0.9891330003738404 0.0 0.0 43.105753226180866 35.0 0.0 no 9566 chrXII_921049 26004 high_effect YLR399C 528 - TCCAATTTCACTGGGTCAAC L|182|F silent|TTG>TTA|L|182 D|183|H D|183|N BDF1 BromoDomain Factor 686.0 0 0 0 0 -1.3193137720705943 P35817 1.0031700134277344 0.9202659726142884 0.9315000176429749 0.0 0.0326271653175354 1.0 47.4502818881744 45.0 0.0 no 9567 chrXII_921050r 26005 high_effect YLR399C 524 + ACCTGTTGACCCAGTGAAAT P|176|R P|176|L P|176|A P|176|S BDF1 BromoDomain Factor 686.0 0 0 0 0 -1.179914828324771 P35817 0.9753050208091736 0.9834169745445251 1.0002000331878662 0.9924110174179076 0.0 0.0 0.0 0.0 49.23028141389768 45.0 0.0 no 9568 chrXII_921133 26007 high_effect YLR399C 444 - TTCTGCTGGTGCTTTGGTAT Q|154|H silent|CAG>CAA|Q|154 Q|153|H silent|CAG>CAA|Q|153 BDF1 BromoDomain Factor 686.0 0 0 0 0 0.6802901313475445 P35817 0.9317049980163574 1.0006899833679201 0.13776405155658722 0.0 53.761584254753025 45.0 0.0 no 9569 chrXII_921246 26012 high_effect YLR399C 331 - TTCATCTAAATCCTCTTGTT E|117|Q E|117|K D|116|H D|116|N BDF1 BromoDomain Factor 686.0 0 0 0 0 -0.4482928046852003 P35817 1.006500005722046 0.9951429963111876 0.9959579706192015 1.006500005722046 0.46475073695182795 0.7208191752433777 0.11600568890571596 0.4699971377849579 43.43602929804496 30.0 0.0 no 9570 chrXII_921221r 26013 high_effect YLR399C 353 + CTCAAAACAAGAACTTCCGA S|119|* S|119|L BDF1 BromoDomain Factor 686.0 0 0 0 0 -0.3487845705206042 P35817 0.9816009998321532 0.2954544126987457 39.32607446585251 40.0 0.0 no 9571 chrXII_921306 26017 high_effect YLR399C 271 - TTCGTCTTCTGCGCCACTTC E|97|Q E|97|K D|96|H D|96|N BDF1 BromoDomain Factor 686.0 0 1 0 0 -0.10461434008268296 P35817 1.006500005722046 0.9951429963111876 0.9959579706192015 1.006500005722046 0.3685902059078217 0.6513185501098633 0.12127761542797087 0.4862614274024963 57.5130465585687 55.00000000000001 0.0 no 9572 chrXII_921379 26021 high_effect YLR399C 198 - CCGTTCTCTGCAAGTCCAGC G|73|R G|73|S E|71|D silent|GAG>GAA|E|71 BDF1 BromoDomain Factor 686.0 0 0 0 0 0.5402758216384621 P35817 0.978958010673523 0.9976239800453186 0.999334990978241 0.5034556388854979 0.8164701461791992 0.3531781136989593 58.84368637781296 60.0 0.0 no 9573 chrXII_921558 26029 high_effect YLR399C 19 - GACATCCACATCGTTCTGTA V|13|L V|13|I D|12|H D|12|N BDF1 BromoDomain Factor 686.0 0 0 0 0 0.4427232219199485 P35817 1.0000799894332886 1.0070600509643557 0.9959579706192015 1.006500005722046 49.95782166921555 45.0 0.0 no 9574 chrXII_921559 26030 high_effect YLR399C 18 - ACATCCACATCGTTCTGTAC V|13|L V|13|I D|12|H D|12|N BDF1 BromoDomain Factor 686.0 0 0 0 0 -0.4743337806485444 P35817 1.0000799894332886 1.0070600509643557 0.9959579706192015 1.006500005722046 49.19424395895357 45.0 0.0 no 9575 chrXII_925612 26032 high_effect YLR403W 44 + TACTACTACGACGGCTACAT T|16|S T|16|I T|17|S T|17|I SFP1 Split Finger Protein 683.0 0 0 0 0 -0.589878401338375 P32432 0.9910879731178284 0.9891359806060792 0.9910879731178284 0.9891359806060792 45.66644327732581 45.0 1.0 no 9576 chrXII_925603 26033 high_effect YLR403W 35 + GGCTACTAGTACTACTACGA A|13|G A|13|V T|14|S T|14|I SFP1 Split Finger Protein 683.0 0 0 0 0 -0.6399404607226329 P32432 0.9916989803314208 0.9909250140190125 0.9910879731178284 0.9891359806060792 46.638888770130215 45.0 1.0 no 9577 chrXII_925715 26035 high_effect YLR403W 147 + AACAATTCGGATTCTTCTAA N|50|K silent|AAC>AAT|N|50 SFP1 Split Finger Protein 683.0 0 0 0 0 0.4163896620760617 P32432 0.9845200181007384 38.41723602015463 30.0 1.0 no 9578 chrXII_925834 26037 high_effect YLR403W 266 + CCAAACGCTACTAACTCCAC Q|90|E Q|90|* T|91|R T|91|M SFP1 Split Finger Protein 683.0 0 0 0 0 -0.07110724975763562 P32432 1.0024600028991701 0.9773380160331726 0.9916599988937378 0.5212738513946533 0.04715482890605927 0.0209003072232008 46.71447598060439 50.0 1.0 no 9579 chrXII_925851 26039 high_effect YLR403W 283 + CACAGGACATTGCCAAGTTA Q|96|E Q|96|* SFP1 Split Finger Protein 683.0 0 0 0 0 -0.3262611402139857 P32432 0.9358479976654052 0.2241378128528595 47.503482015146176 45.0 1.0 no 9580 chrXII_925878 26040 high_effect YLR403W 310 + AATCAATAGCCCATTCTCAA S|105|* S|105|L SFP1 Split Finger Protein 683.0 0 0 0 0 -1.494970091944195 P32432 0.9753659963607788 0.0 44.470189714191925 35.0 1.0 no 9581 chrXII_925913 26042 high_effect YLR403W 345 + TCATGGGGATCCATTAGTGT S|116|* S|116|L SFP1 Split Finger Protein 683.0 0 0 0 0 -2.8412839129979646 P32432 0.9753659963607788 0.0 51.199194690064246 45.0 1.0 yes 9582 chrXII_925923r 26043 high_effect YLR403W 358 - TAACCAAGAACCAACACTAA W|125|C W|125|* W|125|S W|125|* SFP1 Split Finger Protein 683.0 0 0 0 0 0.20141489866853185 P32432 0.9440850019454956 0.9438130259513856 0.0 0.0 38.067714867932246 35.0 1.0 no 9583 chrXII_926262r 26045 high_effect YLR403W 697 - CATCGGTATTTGTGACATAT silent|CCG>CCC|P|238 silent|CCG>CCA|P|238 SFP1 Split Finger Protein 683.0 0 0 0 0 0.07631999944455846 P32432 42.55380731530778 35.0 1.0 no 9584 chrXII_926366 26046 high_effect YLR403W 798 + GCCGCTAATACAAAAAATGC silent|GCC>GCG|A|267 silent|GCC>GCT|A|267 A|267|G A|267|V SFP1 Split Finger Protein 683.0 0 0 0 0 0.5646776839568531 P32432 0.9916989803314208 0.9909250140190125 0.5769656896591187 0.35930752754211426 39.52363864366748 40.0 1.0 no 9585 chrXII_926389 26047 high_effect YLR403W 821 + TCATAAGACTAATACTATGC H|275|D H|275|Y SFP1 Split Finger Protein 683.0 0 0 0 0 0.4025910950764563 P32432 0.9914770126342772 0.9916279911994934 0.06338167190551758 0.04262873902916908 35.83597080550578 30.0 1.0 no 9586 chrXII_926490r 26048 high_effect YLR403W 925 - ATGCTGAGATTGTCGTATTG Q|314|H silent|CAG>CAA|Q|314 SFP1 Split Finger Protein 683.0 0 0 0 0 0.15671224801478334 P32432 1.0004700422286987 0.4110715091228485 44.368204106761816 40.0 1.0 no 9587 chrXII_926557 26049 high_effect YLR403W 989 + TTCTGTAAATCATACATCAG S|331|C S|331|F SFP1 Split Finger Protein 683.0 0 0 0 0 0.8220245326379032 P32432 0.9879119992256165 0.9685909748077391 0.03793681040406227 0.04397489875555039 36.97244445294415 30.0 1.0 no 9588 chrXII_926582 26050 high_effect YLR403W 1014 + GTACCCACACCGAGTGTAAT P|340|A P|340|S P|340|R P|340|L SFP1 Split Finger Protein 683.0 0 0 0 0 -0.9806973161449408 P32432 1.0002000331878662 0.9924110174179076 0.9753050208091736 0.9834169745445251 0.8594479560852051 0.8285412788391113 0.5594729781150818 0.3797938227653504 51.7495422536395 50.0 1.0 no 9589 chrXII_926585r 26051 high_effect YLR403W 1020 - GAACCCATTACACTCGGTGT G|346|A G|346|D G|346|R G|346|S SFP1 Split Finger Protein 683.0 0 0 0 0 -0.3573246959989093 P32432 0.9901490211486816 0.9780880212783812 0.9727219939231871 0.991388976573944 0.8592387437820435 0.6473870277404785 0.5652246475219727 0.7813370227813721 51.420087116896184 50.0 1.0 no 9590 chrXII_926622r 26052 high_effect YLR403W 1057 - CACATTTGGATTTGCAGTTG V|359|L V|359|M SFP1 Split Finger Protein 683.0 0 0 0 0 0.7615880350000375 P32432 0.9938480257987976 1.0022799968719482 44.737117113863924 40.0 1.0 no 9591 chrXII_926635 26053 high_effect YLR403W 1067 + TCCAAATGTGATATCTATAA P|357|R P|357|L P|357|A P|357|S SFP1 Split Finger Protein 683.0 0 0 0 0 -0.8521570821091942 P32432 0.9753050208091736 0.9834169745445251 1.0002000331878662 0.9924110174179076 36.06768562315318 25.0 1.0 no 9592 chrXII_926693 26057 high_effect YLR403W 1125 + TCTCAACAACTACATCTGAA Q|377|E Q|377|* S|376|C S|376|F SFP1 Split Finger Protein 683.0 0 0 0 0 -0.07362891856748993 P32432 1.0036499500274658 0.989100992679596 0.9697790145874025 0.45723611116409296 0.132741317152977 0.3600800633430481 39.19314899235633 35.0 1.0 no 9593 chrXII_926848 26058 high_effect YLR403W 1280 + ACACAATTCTAATATTAACA H|428|Q silent|CAC>CAT|H|428 H|428|D H|428|Y SFP1 Split Finger Protein 683.0 0 0 0 0 0.2004290064991353 P32432 1.0022599697113037 0.9914770126342772 0.9916279911994934 0.4724619090557098 0.3792982697486877 1.0 32.39780411924056 20.0 1.0 no 9594 chrXII_926919r 26060 high_effect YLR403W 1354 - ATTCCTGGACGTTTTGTTCA R|457|S silent|AGG>AGA|R|457 R|457|T R|457|K SFP1 Split Finger Protein 683.0 0 0 0 0 -0.02651778730635424 P32432 0.9618290066719056 0.9788659811019896 0.9986129999160768 0.7955990433692932 0.5897549986839294 0.9367348551750184 49.91459829402515 40.0 1.0 no 9595 chrXII_926977 26061 high_effect YLR403W 1409 + TCAAACCGATTTATCACCTC Q|471|E Q|471|* T|472|S T|472|I SFP1 Split Finger Protein 683.0 0 0 0 0 0.003287816151638312 P32432 1.0024600028991701 0.9910879731178284 0.9891359806060792 0.706642746925354 0.8126776814460754 0.4806722104549408 44.56324561555033 40.0 1.0 no 9596 chrXII_927058r 26064 high_effect YLR403W 1493 - CGACAGAGTTCATGGAATTG V|504|L V|504|I SFP1 Split Finger Protein 683.0 0 0 0 0 -0.2829241687662524 P32432 0.9938480257987976 1.0008200407028198 0.6061162948608398 0.4990049302577973 42.23474278388403 45.0 1.0 no 9597 chrXII_935180r 26065 essential YLR409C 2031 + TTACCTAGCACATCTGTTCG P|679|A P|679|S P|679|R P|679|L 0 0 0 0 0.6051566026677055 Q06078 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.03017223253846168 0.027922909706830982 0.00911811273545027 0.0067695947363972655 2.9031798839569087 4.775420188903809 17.962400436401367 8.374959945678711 49.120010213359826 45.0 0.0 no 9598 chrXII_935212 26066 essential YLR409C 2002 - TGCAAATTCAGACTCATCGA A|674|P A|674|T 0 0 0 0 0.30071694279433603 Q06078 0.9573720097541808 0.9523990154266356 0.3009377419948578 0.9618245363235474 1.7272800207138062 0.9917399883270264 43.013977804056886 40.0 0.0 no 9599 chrXII_935285r 26067 essential YLR409C 1926 + ACTACCCATGTTACTGGTAA T|643|S T|643|I T|644|S T|644|I 0 0 0 0 -0.5502303139322497 Q06078 0.9491789937019348 0.9472420215606691 0.9491789937019348 0.9472420215606691 0.0 0.0 0.07507803291082382 0.09427402913570404 1.8801599740982056 1.8270800113677976 1.1651999950408936 0.5887200236320496 47.66753660660163 40.0 0.0 no 9600 chrXII_935369 26068 essential YLR409C 1845 - CCATCGATACATCCTCCGGT G|622|R G|622|S D|621|H D|621|N 0 0 0 0 -0.1146801374964012 Q06078 0.941340982913971 0.951104998588562 0.9486550092697144 0.956179976463318 0.3431256413459778 0.6656904816627502 0.0 0.0 9.845959663391113 6.136179924011231 9.927240371704102 1.4606000185012815 55.78974573058957 55.00000000000001 0.0 no 9601 chrXII_935444r 26071 essential YLR409C 1767 + GCATTTGATTTCTCACCTGA A|590|G A|590|V 0 0 0 0 0.5604369093413023 Q06078 0.9484469890594482 0.9504740238189696 0.2951744496822357 0.16743750870227814 0.10760000348091124 2.0314600467681885 48.95265615436614 40.0 0.0 no 9602 chrXII_935445r 26072 essential YLR409C 1766 + TGCATTTGATTTCTCACCTG A|590|G A|590|V 0 0 0 0 0.2863822202061725 Q06078 0.9484469890594482 0.9504740238189696 0.2951744496822357 0.16743750870227814 0.10760000348091124 2.0314600467681885 47.68868300523627 40.0 0.0 no 9603 chrXII_935699r 26073 essential YLR409C 1512 + GTCACCGGTATATCCTTAGA silent|GTC>GTG|V|505 silent|GTC>GTT|V|505 T|506|S T|506|I 0 0 0 0 0.018178162767620642 Q06078 0.9491789937019348 0.9472420215606691 0.12248948216438292 0.0040240813978016385 0.7762200236320496 1.96616005897522 51.08518615808021 45.0 0.0 no 9604 chrXII_935758 26074 essential YLR409C 1456 - ACCACTTTGCATATTATAGA G|492|R G|492|S G|492|A G|492|D 0 0 0 0 0.06378786418679645 Q06078 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 13.711400032043455 9.495779991149902 7.8622798919677725 14.17393970489502 42.44019503429712 30.0 0.0 no 9605 chrXII_935759r 26075 essential YLR409C 1452 + ACCATCTATAATATGCAAAG silent|ACC>ACG|T|485 silent|ACC>ACT|T|485 T|485|S T|485|I 0 0 0 0 -0.6284322010627357 Q06078 0.9491789937019348 0.9472420215606691 0.4659849405288696 0.08091703057289124 1.170240044593811 -0.29899999499320984 36.96464967534649 30.0 0.0 no 9606 chrXII_936031r 26081 essential YLR409C 1180 + ACAAGAAACAAGATGGCGGC H|394|Q silent|CAC>CAT|H|394 0 0 0 0 -0.2321931079768376 Q06078 0.9588389992713928 0.5929924249649048 42.73854419531187 50.0 0.0 no 9607 chrXII_936035r 26082 essential YLR409C 1176 + TTACACAAGAAACAAGATGG H|394|D H|394|Y H|394|Q silent|CAC>CAT|H|394 0 0 0 0 -0.2816591703686863 Q06078 0.9473130106925964 0.9489949941635132 0.9588389992713928 0.6274678707122803 0.10269468277692796 0.5929924249649048 34.113999580984284 35.0 0.0 no 9608 chrXII_936155 26085 essential YLR409C 1059 - TCAGCAAACGCAATGTATGA D|360|H D|360|N A|359|P A|359|T 0 0 0 0 -0.10947084003701546 Q06078 0.9486550092697144 0.956179976463318 0.9573720097541808 0.9523990154266356 0.05101317167282105 0.2190917730331421 0.24785853922367096 0.6537154912948608 4.188620090484618 2.5550599098205566 4.678460121154785 -0.6269599795341492 41.99553443617799 40.0 0.0 no 9609 chrXII_936194 26087 essential YLR409C 1020 - CCTCTGGAACGTAGATATCT R|346|T R|346|K G|347|R G|347|R 0 0 0 0 0.3028226442781038 Q06078 0.932735025882721 0.955805003643036 0.941340982913971 0.941340982913971 0.0 0.0 0.028542753309011463 0.028542753309011463 0.3319999873638153 0.3634800016880035 4.525559902191162 4.525559902191162 46.893549787285345 45.0 0.0 no 9610 chrXII_936194r 26088 essential YLR409C 1017 + CCAAGATATCTACGTTCCAG P|340|R P|340|L 0 0 0 0 0.16242064295672504 Q06078 0.9432820081710817 0.9430609941482544 0.0 0.0 10.3889799118042 6.145820140838622 46.41527516938385 45.0 0.0 no 9611 chrXII_936242r 26091 essential YLR409C 969 + TTCGATCCGTCATTATCTCA F|324|L silent|TTC>TTT|F|324 P|326|A P|326|S 0 0 0 0 0.2539881436507084 Q06078 0.9387490153312684 0.9562489986419678 0.9498909711837769 0.0 0.6277896761894226 0.580593466758728 1.3150800466537476 0.25892001390457153 0.3288399875164032 48.584470596417816 40.0 0.0 no 9612 chrXII_936258 26092 essential YLR409C 956 - GATCGAAAACGTACTCCTTC D|325|H D|325|N 0 0 0 0 0.30278714565246984 Q06078 0.9486550092697144 0.956179976463318 0.0 0.0 1.320580005645752 0.8350399732589722 43.216222144316475 45.0 0.0 no 9613 chrXII_936289 26093 essential YLR409C 925 - ACCACCTGATGTAACAATAA G|315|R G|315|S G|315|A G|315|D 0 0 0 0 -2.1698334856490096 Q06078 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.27760133147239685 0.6378901600837708 0.4995666146278381 0.7815393805503845 0.6771600246429443 0.6573399901390076 0.21417999267578125 2.840980052947998 41.097429244560146 35.0 0.0 yes 9614 chrXII_936259 26096 essential YLR409C 955 - ATCGAAAACGTACTCCTTCA D|325|H D|325|N 0 0 0 0 -0.11184514081152984 Q06078 0.9486550092697144 0.956179976463318 0.0 0.0 1.320580005645752 0.8350399732589722 43.32341527868744 40.0 0.0 no 9615 chrXII_936347r 26097 essential YLR409C 864 + AACATTCATAGAGAATCGTA N|289|K silent|AAC>AAT|N|289 H|291|D H|291|Y 0 0 0 0 0.13505933975586865 Q06078 0.9439849853515624 0.9473130106925964 0.9489949941635132 0.2952971160411835 0.0 0.0 -0.5128399729728699 4.379819869995116 2.2500600814819336 36.88923866890286 30.0 0.0 no 9616 chrXII_936455r 26099 essential YLR409C 756 + TCATTGAGTTTCAGAACCGA S|253|* S|253|L 0 0 0 0 -0.011158371192598188 Q06078 0.9298099875450134 0.022998763248324398 3.634979963302612 44.862195422475054 40.0 0.0 no 9617 chrXII_936646r 26103 essential YLR409C 565 + TACTTTTTAACGTCAGAACC L|190|V L|190|F 0 0 0 0 -1.2844264732144541 Q06078 0.9512209892272948 0.9587849974632264 0.5918457508087158 0.0193012747913599 1.7618399858474731 6.524320125579834 40.62803302846918 35.0 0.0 no 9618 chrXII_936647r 26104 essential YLR409C 564 + TTACTTTTTAACGTCAGAAC L|190|V L|190|F 0 0 0 0 0.3539569696868933 Q06078 0.9512209892272948 0.9587849974632264 0.5918457508087158 0.0193012747913599 1.7618399858474731 6.524320125579834 37.05991074599956 30.0 0.0 no 9619 chrXII_936739 26105 essential YLR409C 475 - GCCACCTTGAATTTCAGTAA G|165|R G|165|S G|165|A G|165|D 0 0 0 0 -0.18245761004306474 Q06078 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.577445924282074 0.8159719109535217 0.8733267188072205 0.6318106055259705 1.5815800428390503 1.386579990386963 1.179059982299805 -0.03610000014305115 47.32815327736199 40.0 0.0 no 9620 chrXII_936938r 26111 essential YLR409C 273 + GCAGCATATGAAAACAAGGT A|92|G A|92|V A|93|G A|93|V 0 0 0 0 -0.5358403523405717 Q06078 0.9484469890594482 0.9504740238189696 0.9484469890594482 0.9504740238189696 0.4697084128856659 0.3504314422607422 0.02621435932815075 0.018940679728984836 2.0527799129486084 -1.3218400478363037 2.0083799362182617 1.4530800580978394 40.76435047322229 40.0 0.0 no 9621 chrXII_937100 26113 essential YLR409C 114 - CCCAATGTACCAGTAGCAAA L|44|F silent|TTG>TTA|L|44 G|45|R G|45|R 0 0 0 0 0.016476191051363276 Q06078 0.9587849974632264 0.941340982913971 0.941340982913971 0.5267399549484253 0.0 0.0 -0.09740000218153 2.5927999019622803 2.5927999019622803 48.003219468996114 45.0 0.0 no 9622 chrXII_937131 26115 essential YLR409C 83 - TGCTAACATTACCAATAATC S|34|T S|34|N V|33|L V|33|I 0 0 0 0 0.6298549471888505 Q06078 0.9512869715690612 0.9536849856376648 0.9539830088615416 0.9574310183525084 0.5299140214920044 0.02074082568287849 0.02270379476249218 0.03674483299255371 0.21184000372886655 0.8234999775886536 2.1101000308990483 0.07453999668359756 37.571448269969956 30.0 0.0 no 9623 chrXII_973551r 26117 essential YLR424W 159 - TTCGTTAATTTTGAGATCGT silent|ACG>ACC|T|59 silent|ACG>ACA|T|59 SPP382 Suppressor of PrP38 #2 708.0 0 0 0 0 -0.7326267020971389 Q06411 40.45088607508569 30.0 1.0 no 9624 chrXII_973560 26118 essential YLR424W 165 + TCAAAATTAACGAAGACATA S|56|* S|56|L SPP382 Suppressor of PrP38 #2 708.0 0 1 0 0 1.395315352820594 Q06411 0.9298099875450134 0.22173772752285004 31.017089229174303 25.0 1.0 no 9625 chrXII_973589 26119 essential YLR424W 194 + TGCGAAGTTACTTTCGAGTA A|66|G A|66|V SPP382 Suppressor of PrP38 #2 708.0 0 0 0 0 0.6967930336442035 Q06411 0.9484469890594482 0.9504740238189696 0.0 0.0 44.332085160173385 40.0 1.0 no 9626 chrXII_973683r 26124 essential YLR424W 291 - CCTAGACCTGCATTGTGCAT G|104|R G|104|R G|102|A G|102|D SPP382 Suppressor of PrP38 #2 708.0 0 0 0 0 -0.27920371021655754 Q06411 0.941340982913971 0.941340982913971 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 54.36904338097702 50.0 1.0 no 9627 chrXII_973802 26128 essential YLR424W 407 + ATTCAATAAAACCTCCACGG F|137|L silent|TTC>TTT|F|137 SPP382 Suppressor of PrP38 #2 708.0 0 0 0 0 0.3623454764482258 Q06411 0.9387490153312684 0.40368399024009705 41.862035626469655 40.0 1.0 no 9628 chrXII_973813r 26129 essential YLR424W 421 - TTCGCCTAAAACCTCCGTGG E|147|Q E|147|K G|146|A G|146|D SPP382 Suppressor of PrP38 #2 708.0 0 0 0 0 -0.9003386837211398 Q06411 0.956179976463318 0.9475290179252625 0.9499930143356324 0.9446240067481996 0.5206638574600221 0.7544061541557312 0.8438320755958557 0.8704829812049866 51.95523366683608 55.00000000000001 1.0 no 9629 chrXII_973816r 26130 essential YLR424W 424 - CGCTTCGCCTAAAACCTCCG A|148|P A|148|T E|147|Q E|147|K SPP382 Suppressor of PrP38 #2 708.0 0 0 0 0 0.09093351236117886 Q06411 0.9573720097541808 0.9523990154266356 0.956179976463318 0.9475290179252625 0.2722818851470947 0.5702109336853027 0.5206638574600221 0.7544061541557312 53.13546466716088 60.0 1.0 no 9630 chrXII_973958 26134 essential YLR424W 563 + GCCGAAAAAAGATGTTGTTG P|189|R P|189|L P|189|A P|189|S SPP382 Suppressor of PrP38 #2 708.0 0 0 0 0 -0.14884570644161702 Q06411 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 39.08668803975172 40.0 1.0 no 9631 chrXII_974038r 26135 essential YLR424W 646 - GACTTGCACTTCTAACGGAG V|222|L V|222|I silent|GTG>GTC|V|220 silent|GTG>GTA|V|220 SPP382 Suppressor of PrP38 #2 708.0 0 0 0 0 1.321979614751762 Q06411 0.9539830088615416 0.9574310183525084 1.0 0.3635005652904511 46.478329749666045 50.0 1.0 no 9632 chrXII_974134r 26137 essential YLR424W 742 - AGCACCAATCTTATCATACA A|254|P A|254|T G|253|A G|253|D SPP382 Suppressor of PrP38 #2 708.0 0 0 0 0 0.20481864407930656 Q06411 0.9573720097541808 0.9523990154266356 0.9499930143356324 0.9446240067481996 0.3443553447723389 0.7224351763725281 0.7389347553253174 0.6532033681869507 44.338349150383245 35.0 1.0 no 9633 chrXII_974170r 26139 essential YLR424W 778 - CCTATCTATGAGCTCGTCGT R|266|T R|266|K D|265|H D|265|N SPP382 Suppressor of PrP38 #2 708.0 0 0 0 0 -0.21843927236109487 Q06411 0.932735025882721 0.955805003643036 0.9486550092697144 0.956179976463318 0.12487978488206865 1.0 0.0 0.0 52.886360781510746 50.0 1.0 no 9634 chrXII_974256r 26140 essential YLR424W 864 - AACTCATCAAGTATATCGTT E|294|D silent|GAG>GAA|E|294 E|294|Q E|294|K SPP382 Suppressor of PrP38 #2 708.0 0 0 0 0 0.2968138522433102 Q06411 0.94931298494339 0.956179976463318 0.9475290179252625 0.5553581118583679 0.8120522499084473 0.7381383180618286 39.49487993627787 30.0 1.0 no 9635 chrXII_974373 26141 essential YLR424W 978 + AAACTCAAAAAATTTTGGGA L|328|V L|328|F silent|CTC>CTG|L|328 silent|CTC>CTT|L|328 SPP382 Suppressor of PrP38 #2 708.0 0 0 0 0 1.2644143680407014 Q06411 0.9512209892272948 0.9587849974632264 0.07638534903526306 0.2237055450677872 31.88330482265019 25.0 1.0 no 9636 chrXII_974423 26142 essential YLR424W 1028 + CAGCGCTATCACCCTATTAC S|344|R silent|AGC>AGT|S|344 A|345|G A|345|V SPP382 Suppressor of PrP38 #2 708.0 0 0 0 0 0.8197699514436747 Q06411 0.9417110085487366 0.9484469890594482 0.9504740238189696 0.5047240257263184 0.02476627379655838 0.9804624319076538 51.99932021347701 50.0 1.0 no 9637 chrXII_974452 26143 essential YLR424W 1057 + AACAAGTGCTAAGTTTTATC Q|354|E Q|354|* SPP382 Suppressor of PrP38 #2 708.0 0 0 0 0 -0.9703080422424448 Q06411 0.9590039849281312 1.0 37.59850100924888 30.0 1.0 no 9638 chrXII_974508r 26145 essential YLR424W 1116 - TCTAATTCCTGTAATAGCTT D|379|H D|379|N SPP382 Suppressor of PrP38 #2 708.0 0 0 0 0 0.4363888855762755 Q06411 0.9486550092697144 0.956179976463318 0.10956668108701706 0.4941864013671875 42.499573727733825 30.0 1.0 no 9639 chrXII_974557 26147 essential YLR424W 1162 + ACCATGTTTCGCCAAGAATA H|389|D H|389|Y D|388|E silent|GAC>GAT|D|388 SPP382 Suppressor of PrP38 #2 708.0 0 0 0 0 0.2495630561168101 Q06411 0.9473130106925964 0.9489949941635132 0.9532920122146606 0.6179236769676208 0.2745409309864044 0.1359533667564392 46.41052553973021 40.0 1.0 no 9640 chrXII_974558r 26148 essential YLR424W 1166 - CCCATATTCTTGGCGAAACA W|395|S W|395|* W|395|C W|395|* SPP382 Suppressor of PrP38 #2 708.0 0 0 0 0 -1.3446778441700595 Q06411 0.8858469724655151 0.8858469724655151 0.01058350130915642 0.006253519095480442 47.83281132053196 45.0 1.0 no 9641 chrXII_974775r 26150 essential YLR424W 1383 - CACAGCTCGTCCAGGAATTT silent|CTG>CTC|L|467 silent|CTG>CTA|L|467 E|466|D silent|GAG>GAA|E|466 SPP382 Suppressor of PrP38 #2 708.0 0 0 0 0 -1.187983636919001 Q06411 0.94931298494339 0.6480157375335693 51.2708524182999 50.0 1.0 no 9642 chrXII_974783r 26151 essential YLR424W 1391 - GTCTTTCCCACAGCTCGTCC R|470|T R|470|K E|469|Q E|469|K SPP382 Suppressor of PrP38 #2 708.0 0 0 0 0 -0.08935167989325273 Q06411 0.932735025882721 0.955805003643036 0.956179976463318 0.9475290179252625 0.2016838937997818 1.0 0.3571409285068512 0.4382149279117584 62.63712748427048 60.0 1.0 no 9643 chrXII_974810 26152 essential YLR424W 1415 + TGACCCCATCTACGAGTTAG D|473|E silent|GAC>GAT|D|473 P|474|A P|474|S SPP382 Suppressor of PrP38 #2 708.0 0 0 0 0 0.17802441145161338 Q06411 0.9532920122146606 0.9562489986419678 0.9498909711837769 0.3587823808193207 0.1959118545055389 0.10891571640968324 50.96678819097178 50.0 1.0 no 9644 chrXII_974813r 26153 essential YLR424W 1421 - AATCCTCTAACTCGTAGATG D|480|H D|480|N E|479|D silent|GAG>GAA|E|479 SPP382 Suppressor of PrP38 #2 708.0 0 0 0 0 0.05631952272150244 Q06411 0.9486550092697144 0.956179976463318 0.94931298494339 0.10630548000335692 0.36771705746650696 0.3863362967967987 42.82872742680326 40.0 1.0 no 9645 chrXII_974815r 26155 essential YLR424W 1423 - CCAATCCTCTAACTCGTAGA W|481|S W|481|* D|480|H D|480|N SPP382 Suppressor of PrP38 #2 708.0 0 0 0 0 0.29702375335072884 Q06411 0.8858469724655151 0.9486550092697144 0.956179976463318 0.3069312572479248 0.10630548000335692 0.36771705746650696 47.81157891528392 45.0 1.0 no 9646 chrXII_974909r 26156 essential YLR424W 1517 - ACTGTTTTGGATGAAAATAA Q|512|H silent|CAG>CAA|Q|512 SPP382 Suppressor of PrP38 #2 708.0 0 0 0 0 -0.37591739033185145 Q06411 0.9570760130882264 0.20474271476268768 33.78169291241704 25.0 1.0 no 9647 chrXII_974922r 26157 essential YLR424W 1530 - ATCATCAATTCATACTGTTT M|516|I M|516|I L|515|F silent|TTG>TTA|L|515 SPP382 Suppressor of PrP38 #2 708.0 0 0 0 0 0.13494017287781726 Q06411 0.9553959965705872 0.9553959965705872 0.9587849974632264 0.3605884611606598 0.3605884611606598 0.5292550325393677 39.41066269324148 25.0 1.0 no 9648 chrXII_993506r 26161 essential YLR430W 75 - GCTAGCTGAACATCGCTATT A|32|P A|32|T Q|30|H silent|CAG>CAA|Q|30 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.60545103998079 Q00416 0.9573720097541808 0.9523990154266356 0.9570760130882264 48.45610034685546 45.0 1.0 no 9649 chrXII_993523 26163 essential YLR430W 89 + GCTAGCTACCGTCTATACCA L|31|V silent|CTA>TTA|L|31 A|32|G A|32|V SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.5496204930547736 Q00416 0.9512209892272948 0.9484469890594482 0.9504740238189696 54.43321188587215 50.0 1.0 no 9650 chrXII_993531r 26164 essential YLR430W 100 - AGACTTTGCCTTGGTATAGA K|39|N silent|AAG>AAA|K|39 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -0.15232592068211695 Q00416 0.9355990290641784 48.0776943678104 40.0 1.0 no 9651 chrXII_993586 26165 essential YLR430W 152 + CACAAATCCAAATATTCAAG T|52|R T|52|I SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -0.3657700596010878 Q00416 0.9476869702339172 0.9472420215606691 0.12308503687381744 0.18844878673553467 34.204542787296354 30.0 1.0 no 9652 chrXII_993600 26166 essential YLR430W 166 + TTCAAGAGGCAAAATTATTA Q|57|E Q|57|* SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.4312224478735796 Q00416 0.9590039849281312 0.2480932176113129 34.41129918052121 25.0 1.0 no 9653 chrXII_993718 26169 essential YLR430W 284 + CTCATTCAATGAAGAAGCTA S|96|* S|96|L F|97|L silent|TTC>TTT|F|97 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.3267526965832391 Q00416 0.9298099875450134 0.9387490153312684 0.0762675479054451 0.12069594115018845 38.92839115288331 35.0 1.0 no 9654 chrXII_993791 26170 essential YLR430W 357 + TGCATTCTAAATTTTGCGAG C|120|W silent|TGC>TGT|C|120 L|122|V silent|CTA>TTA|L|122 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 1.3277984155147855 Q00416 0.9286419749259948 0.9512209892272948 0.0 0.6307021379470825 40.763720049943636 35.0 1.0 no 9655 chrXII_993792 26171 essential YLR430W 358 + GCATTCTAAATTTTGCGAGA C|120|W silent|TGC>TGT|C|120 L|122|V silent|CTA>TTA|L|122 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -0.2977177031222087 Q00416 0.9286419749259948 0.9512209892272948 0.0 0.6307021379470825 41.90281669326879 35.0 1.0 no 9656 chrXII_993886 26175 essential YLR430W 452 + CATCGTATGCCAATGGAGGG I|152|M silent|ATC>ATT|I|152 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -0.9396503834856248 Q00416 0.9598389863967896 0.32906630635261536 50.15685711987487 55.00000000000001 1.0 no 9657 chrXII_993920r 26176 essential YLR430W 489 - ACGGAAATATTTCTAAGAAT V|170|L V|170|I SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.4762634363778338 Q00416 0.9539830088615416 0.9574310183525084 0.3363095819950104 0.2429343163967133 33.11855713359415 25.0 1.0 no 9658 chrXII_994002 26177 essential YLR430W 568 + TCTGTAATCCGCATATGTTG silent|CTC>CTG|L|190 silent|CTC>CTT|L|190 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.21302897901266515 Q00416 45.69050483995409 40.0 1.0 no 9659 chrXII_994075 26178 essential YLR430W 641 + CGACACAAAGCATCGTTTGT D|215|E silent|GAC>GAT|D|215 T|216|R T|216|I SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -0.6391686618375181 Q00416 0.9532920122146606 0.9476869702339172 0.9472420215606691 0.8732579946517944 0.6750863194465637 0.1755136251449585 44.912984985935104 45.0 1.0 no 9660 chrXII_994131 26179 essential YLR430W 697 + TATCAGGTGTCATATTTTGC S|234|* S|234|L SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -2.132243597882835 Q00416 0.9298099875450134 0.026385223492980003 44.637961013494596 35.0 1.0 yes 9661 chrXII_994240r 26182 essential YLR430W 809 - CCTCAATAATATCCGGTGTC E|276|Q E|276|K E|276|D silent|GAG>GAA|E|276 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -1.9067359974190845 Q00416 0.956179976463318 0.9475290179252625 0.94931298494339 0.21240153908729556 0.101693257689476 0.31574785709381104 47.3914934916565 45.0 1.0 no 9662 chrXII_994284 26183 essential YLR430W 850 + TCTTACAGAATCCGGCAAAC F|284|L silent|TTC>TTT|F|284 Q|286|E Q|286|* SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -1.9314752719646715 Q00416 0.9387490153312684 0.9590039849281312 0.6639026403427124 0.1519567370414734 44.10619930588165 45.0 1.0 no 9663 chrXII_994295r 26184 essential YLR430W 864 - ACAATCTCTGTCCAGTTTGC V|295|L V|295|M E|293|D silent|GAG>GAA|E|293 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 1.7665936928725 Q00416 0.9539830088615416 0.9587630033493042 0.94931298494339 0.34960973262786865 0.12210817635059355 1.0 50.87620764986696 45.0 1.0 no 9664 chrXII_994327 26186 essential YLR430W 893 + ATTCTGGTCGAGATTACTAC F|299|L silent|TTC>TTT|F|299 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -0.3822333830485687 Q00416 0.9387490153312684 0.2492496371269226 43.731160863021266 40.0 1.0 no 9665 chrXII_994523 26187 essential YLR430W 1089 + ACAATGTTCTTGAATAAATT T|364|R T|364|I SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.8988099586551379 Q00416 0.9476869702339172 0.9472420215606691 0.4219588041305542 0.1602485626935959 32.42343806175114 20.0 1.0 no 9666 chrXII_994752r 26190 essential YLR430W 1321 - TCTAACCATTTGAATTCTTT R|447|T R|447|K V|446|L V|446|I SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.5767222824161016 Q00416 0.932735025882721 0.955805003643036 0.9539830088615416 0.9574310183525084 0.5791372060775757 0.9387806057929992 0.35928577184677124 0.6451029777526855 39.44349247968421 25.0 1.0 no 9667 chrXII_994851 26192 essential YLR430W 1417 + ATTCAGCAACTGCCTTGTTG S|474|* S|474|L A|475|G A|475|V SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -1.997411957222852 Q00416 0.9298099875450134 0.9484469890594482 0.9504740238189696 0.7857010960578918 0.522898256778717 0.06749136000871657 49.96067532839959 45.0 1.0 no 9668 chrXII_994852 26193 essential YLR430W 1418 + TTCAGCAACTGCCTTGTTGA S|474|* S|474|L A|475|G A|475|V SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -0.5515360015309392 Q00416 0.9298099875450134 0.9484469890594482 0.9504740238189696 0.7857010960578918 0.522898256778717 0.06749136000871657 51.20365333562717 45.0 1.0 no 9669 chrXII_994863r 26194 essential YLR430W 1432 - AGTCAACACAGCCCTCAACA L|483|F silent|TTG>TTA|L|483 silent|GTG>GTC|V|482 silent|GTG>GTA|V|482 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.6961056143403671 Q00416 0.9587849974632264 0.14414450526237488 51.6513830968829 50.0 1.0 no 9670 chrXII_995015 26195 essential YLR430W 1581 + AATCCTAACGACTTTTATCC P|529|A P|529|S P|529|R P|529|L SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 1.017988455196498 Q00416 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 1.0 0.8885039687156677 0.6219165325164795 0.7308282256126404 42.61744351815941 35.0 1.0 no 9671 chrXII_995021 26196 essential YLR430W 1587 + AACGACTTTTATCCTGGGCT N|530|K silent|AAC>AAT|N|530 D|531|E silent|GAC>GAT|D|531 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -1.1197539057228898 Q00416 0.9439849853515624 0.9532920122146606 0.9159031510353088 0.3631991744041443 49.78154292563625 45.0 1.0 no 9672 chrXII_995038 26198 essential YLR430W 1604 + GCTAGGTGCTGCTTCTGCAT L|536|V silent|CTA>TTA|L|536 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.4240151756652577 Q00416 0.9512209892272948 0.4089503586292267 59.25369570748518 55.00000000000001 1.0 no 9673 chrXII_995070r 26199 essential YLR430W 1639 - TTCTGCCAATACCATCATCG E|553|Q E|553|K A|552|P A|552|T SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -0.15449284524077062 Q00416 0.956179976463318 0.9475290179252625 0.9573720097541808 0.9523990154266356 0.3507548272609711 1.0 0.317436158657074 0.6551428437232971 48.865391075039156 45.0 1.0 no 9674 chrXII_995168r 26200 essential YLR430W 1737 - TCCAAGACGTTGGTTGAAAT L|585|F silent|TTG>TTA|L|585 E|586|Q E|586|K SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.7826994411123369 Q00416 0.9587849974632264 0.956179976463318 0.9475290179252625 0.4321589767932892 0.4800370931625366 0.7968735694885254 43.022420946200846 40.0 1.0 no 9675 chrXII_995167 26201 essential YLR430W 1733 + TCCAATTTCAACCAACGTCT P|579|R P|579|L P|579|A P|579|S SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -0.004202292723654383 Q00416 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.5749295949935913 0.3165099918842316 0.7756178975105286 0.7831419110298157 46.0885009698211 40.0 1.0 no 9676 chrXII_995410r 26207 essential YLR430W 1979 - GCGATGCATCTTCATCCGCA silent|TCG>TCC|S|666 silent|TCG>TCA|S|666 A|665|P A|665|T SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.2389418653546195 Q00416 0.9573720097541808 0.9523990154266356 0.06789272278547287 0.08389792591333389 56.156796121303046 55.00000000000001 1.0 no 9677 chrXII_995498 26209 essential YLR430W 2064 + TACAATACATTTGACGTTGA Y|689|* silent|TAC>TAT|Y|689 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -0.5318745483586499 Q00416 37.86724529357457 30.0 1.0 no 9678 chrXII_995497 26210 essential YLR430W 2063 + ATACAATACATTTGACGTTG Y|689|* silent|TAC>TAT|Y|689 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.04388429315545538 Q00416 36.73005575580083 30.0 1.0 no 9679 chrXII_995631r 26214 essential YLR430W 2200 - CATCAAAACACGAACAGCAC L|739|F silent|TTG>TTA|L|739 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.3364789852098856 Q00416 0.9587849974632264 0.028099538758397102 39.34748229191922 45.0 1.0 no 9680 chrXII_995632r 26215 essential YLR430W 2201 - CCATCAAAACACGAACAGCA M|740|I M|740|I L|739|F silent|TTG>TTA|L|739 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -0.5616565956768469 Q00416 0.9553959965705872 0.9553959965705872 0.9587849974632264 0.2966718673706055 0.2966718673706055 0.028099538758397102 42.36913086188649 45.0 1.0 no 9681 chrXII_995946 26218 essential YLR430W 2512 + CCTTTAAGAATATGTTGTAT silent|ACC>ACG|T|838 silent|ACC>ACT|T|838 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -0.11734605248117375 Q00416 37.35921454935698 25.0 1.0 no 9682 chrXII_995946r 26219 essential YLR430W 2515 - CCAATACAACATATTCTTAA W|845|S W|845|* L|843|F silent|TTG>TTA|L|843 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -0.3900842349406794 Q00416 0.8858469724655151 0.9587849974632264 0.0 0.0362592563033104 35.75075737865916 25.0 1.0 no 9683 chrXII_996309r 26224 essential YLR430W 2878 - TTCAGCAGAAGAACTAGCAA E|966|Q E|966|K A|965|P A|965|T SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 1.0444334226606031 Q00416 0.956179976463318 0.9475290179252625 0.9573720097541808 0.9523990154266356 0.5834450125694275 0.9128904342651368 0.3341383934020996 0.6732703447341919 41.57973803195762 40.0 1.0 no 9684 chrXII_996333r 26225 essential YLR430W 2902 - TCTTTGTAAATAGTCTGCCC R|974|T R|974|K SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 1.371261829937079 Q00416 0.932735025882721 0.955805003643036 0.4777963161468506 1.0 47.69619023549126 40.0 1.0 no 9685 chrXII_996359 26226 essential YLR430W 2925 + GCTTTATCTTCTTCAATAAC A|976|G A|976|V SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.9225004482190612 Q00416 0.9484469890594482 0.9504740238189696 0.4182789623737335 0.3038530647754669 39.79012492992933 30.0 1.0 no 9686 chrXII_996477 26227 essential YLR430W 3043 + TATCCAAAATGGAATTAGCT S|1016|C S|1016|F silent|TCC>TCG|S|1016 silent|TCC>TCT|S|1016 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.6724716241866177 Q00416 0.945252001285553 0.9294660091400146 0.101173497736454 0.049106035381555564 38.115233303885596 30.0 1.0 no 9687 chrXII_996544 26230 essential YLR430W 3110 + AGCTTTCCATACAAAGAGTA A|1038|G A|1038|V F|1039|L silent|TTC>TTT|F|1039 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.2455108966127045 Q00416 0.9484469890594482 0.9504740238189696 0.9387490153312684 0.4370868504047394 0.470766693353653 0.92700856924057 42.87551377826145 35.0 1.0 no 9688 chrXII_996545 26231 essential YLR430W 3111 + GCTTTCCATACAAAGAGTAG A|1038|G A|1038|V F|1039|L silent|TTC>TTT|F|1039 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.02957575398654805 Q00416 0.9484469890594482 0.9504740238189696 0.9387490153312684 0.4370868504047394 0.470766693353653 0.92700856924057 42.87551377826145 40.0 1.0 no 9689 chrXII_996550r 26232 essential YLR430W 3119 - ACAAACCCCTACTCTTTGTA L|1046|F silent|TTG>TTA|L|1046 G|1045|A G|1045|D SEN1 Splicing ENdonuclease 2231.0 0 1 0 0 -0.2219229171599776 Q00416 0.9587849974632264 0.9499930143356324 0.9446240067481996 0.4956269264221192 0.7567309141159058 0.6139398813247681 48.53596836501221 40.0 1.0 no 9690 chrXII_996580 26233 essential YLR430W 3146 + AAACGACGATAGCAGTAGTG N|1050|K silent|AAC>AAT|N|1050 D|1051|E silent|GAC>GAT|D|1051 SEN1 Splicing ENdonuclease 2231.0 0 1 0 0 0.6416991646663618 Q00416 0.9439849853515624 0.9532920122146606 0.96108478307724 1.0 41.259385959566096 45.0 1.0 no 9691 chrXII_996775r 26238 essential YLR430W 3344 - GCAATATGATTTCATATAGA L|1121|F silent|TTG>TTA|L|1121 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.7112282623305417 Q00416 0.9587849974632264 0.0 36.29150010621152 25.0 1.0 no 9692 chrXII_996776r 26239 essential YLR430W 3345 - TGCAATATGATTTCATATAG L|1121|F silent|TTG>TTA|L|1121 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -0.19601510479344936 Q00416 0.9587849974632264 0.0 35.139875859707786 25.0 1.0 no 9693 chrXII_996824 26240 essential YLR430W 3390 + TATCCTGATGATGAGCCTAT P|1132|A P|1132|S P|1132|R P|1132|L SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.6681099007899973 Q00416 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.0 0.0 0.0 0.0 47.723611145807524 40.0 1.0 no 9694 chrXII_996839r 26241 essential YLR430W 3408 - ACGTCAGAATAATTACCAAT V|1143|L V|1143|I D|1142|H D|1142|N SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -0.2351682194200548 Q00416 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 0.0932527706027031 0.5208752155303955 0.11144863814115524 0.432604044675827 37.823007276504605 30.0 1.0 no 9695 chrXII_996914 26242 essential YLR430W 3480 + CTACTTCTAGAATCTTGGCA L|1162|V L|1162|F L|1163|V silent|CTA>TTA|L|1163 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.04406282082522417 Q00416 0.9512209892272948 0.9587849974632264 0.9512209892272948 0.05401788651943207 0.16349759697914126 0.16645239293575287 45.46345514454998 40.0 1.0 no 9696 chrXII_996968 26243 essential YLR430W 3534 + AAACCTTTCAGTATTATTGT P|1180|A P|1180|S P|1180|R P|1180|L SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -0.2192604280798533 Q00416 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.08254766464233397 0.1884262561798096 0.01172057818621397 0.011401845142245293 39.58230470923064 25.0 1.0 no 9697 chrXII_997033 26244 essential YLR430W 3599 + TGTCGCTAAACAAGTCATAC silent|GTC>GTG|V|1201 silent|GTC>GTT|V|1201 A|1202|G A|1202|V SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.290536158952206 Q00416 0.9484469890594482 0.9504740238189696 0.3003381788730621 0.2253913134336472 40.96441057486868 40.0 1.0 no 9698 chrXII_997040 26245 essential YLR430W 3606 + AAACAAGTCATACAGGATTG Q|1204|E Q|1204|* SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 1.2339886613775406 Q00416 0.9590039849281312 0.816634476184845 36.73571361540871 35.0 1.0 no 9699 chrXII_997128r 26248 essential YLR430W 3697 - TGCTTTCTTGAAATCATCAC A|1239|P A|1239|T K|1237|N silent|AAG>AAA|K|1237 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.07246340113113423 Q00416 0.9573720097541808 0.9523990154266356 0.9355990290641784 0.15609699487686154 0.7318458557128906 0.3112586736679077 41.449390453131116 35.0 1.0 no 9700 chrXII_997150 26249 essential YLR430W 3716 + ACAACATACATGTTTAGCAA Q|1240|E Q|1240|* H|1241|D H|1241|Y SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -0.5780600106508301 Q00416 0.9590039849281312 0.9473130106925964 0.9489949941635132 1.0 0.20872296392917636 1.0 38.60969772805589 30.0 1.0 no 9701 chrXII_997178 26250 essential YLR430W 3744 + ACATTGAAAAATACCAAAGG T|1249|R T|1249|I SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.23120627153559314 Q00416 0.9476869702339172 0.9472420215606691 0.04608193039894104 0.018612336367368698 32.83653267330243 30.0 1.0 no 9702 chrXII_997264 26251 essential YLR430W 3830 + ATCAGAGATATATTGTGTGA S|1278|* S|1278|L SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.0791568939384884 Q00416 0.9298099875450134 0.09213278442621232 39.11149611699301 30.0 1.0 no 9703 chrXII_997375 26252 essential YLR430W 3941 + ACCATCGCCTCCCGTAAATG P|1315|R P|1315|L P|1315|A P|1315|S SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -0.17771281674658945 Q00416 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.012042022310197352 0.011728711426258087 0.08489610999822618 0.21046636998653406 53.82987326124919 55.00000000000001 1.0 no 9704 chrXII_997382r 26255 essential YLR430W 3951 - GCCGCATCCACATTTACGGG silent|GCG>GCC|A|1323 silent|GCG>GCA|A|1323 A|1324|P A|1324|T SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -0.9578815990766876 Q00416 0.9573720097541808 0.9523990154266356 0.2088862806558609 0.659328818321228 56.16595049576927 60.0 1.0 no 9705 chrXII_997385r 26256 essential YLR430W 3954 - TCTGCCGCATCCACATTTAC E|1325|Q E|1325|K A|1324|P A|1324|T SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.04066346290606593 Q00416 0.956179976463318 0.9475290179252625 0.9573720097541808 0.9523990154266356 0.3651880025863648 0.5554271340370178 0.2088862806558609 0.659328818321228 53.715325530587556 50.0 1.0 no 9706 chrXII_997386r 26257 essential YLR430W 3955 - TTCTGCCGCATCCACATTTA E|1325|Q E|1325|K A|1324|P A|1324|T SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -0.370900252835915 Q00416 0.956179976463318 0.9475290179252625 0.9573720097541808 0.9523990154266356 0.3651880025863648 0.5554271340370178 0.2088862806558609 0.659328818321228 53.52897294971989 45.0 1.0 no 9707 chrXII_997490 26260 essential YLR430W 4056 + TCTTTAATTCAGGGTCCACC S|1353|C S|1353|F SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -1.4386798113731962 Q00416 0.945252001285553 0.9294660091400146 0.030487285926938057 0.23100924491882324 51.018325145465326 45.0 1.0 no 9708 chrXII_997665r 26264 essential YLR430W 4234 - TTCGTCCACAGCGGCATTAC E|1418|Q E|1418|K D|1417|H D|1417|N SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -2.3193917873902365 Q00416 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.0 0.0 0.0 0.0 54.31455987037845 55.00000000000001 1.0 yes 9709 chrXII_997688 26265 essential YLR430W 4254 + ATCTGCCTCAGACTGAAGAG I|1419|M silent|ATC>ATT|I|1419 C|1420|W silent|TGC>TGT|C|1420 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -1.2362429124883372 Q00416 0.9598389863967896 0.9286419749259948 0.04185223579406738 0.0037672619801014657 48.2612096182026 50.0 1.0 no 9710 chrXII_997693r 26266 essential YLR430W 4262 - ACACTCCACTCTTCAGTCTG V|1427|L V|1427|M silent|GTG>GTC|V|1427 silent|GTG>GTA|V|1427 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -0.6265285476423367 Q00416 0.9539830088615416 0.9587630033493042 0.0772642195224762 0.014616239815950394 53.0306708249069 50.0 1.0 no 9711 chrXII_997729 26267 essential YLR430W 4295 + GCATCAATTTAAACCTCAAT H|1433|D H|1433|Y Q|1434|E Q|1434|* SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.704741931894609 Q00416 0.9473130106925964 0.9489949941635132 0.9590039849281312 0.4339868128299713 0.06424380093812943 0.8613908886909485 39.21138937373382 30.0 1.0 no 9712 chrXII_997739 26268 essential YLR430W 4305 + AAACCTCAATTGGTCCGTGT P|1437|A P|1437|S P|1437|R P|1437|L SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -2.0015673444734645 Q00416 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.21860060095787048 0.1125224232673645 0.06778327375650406 0.480726420879364 49.06325996888387 45.0 1.0 no 9713 chrXII_997753r 26271 essential YLR430W 4322 - CAACGTCTGACCTACCTACA V|1447|L V|1447|I D|1446|H D|1446|N SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -0.1688205630649237 Q00416 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 0.060288045555353165 0.07364176213741302 0.0 0.0 49.74855155987092 50.0 1.0 no 9714 chrXII_998023r 26277 essential YLR430W 4592 - CACGCATTTCGTCCCTATCA R|1537|P R|1537|H M|1536|I M|1536|I SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -0.10170746769952432 Q00416 0.9099509716033936 0.9570810198783876 0.9553959965705872 0.9553959965705872 0.0 0.0 0.27303004264831543 0.27303004264831543 54.1879634662746 50.0 1.0 no 9715 chrXII_998100r 26280 essential YLR430W 4669 - GTCACTAACCGCCAAGATAT D|1563|H D|1563|N S|1562|T S|1562|N SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.2805310848374073 Q00416 0.9486550092697144 0.956179976463318 0.9512869715690612 0.9536849856376648 0.02258127182722092 0.04859811440110207 0.059726152569055564 0.02120080031454563 47.52622481788166 45.0 1.0 no 9716 chrXII_998101r 26281 essential YLR430W 4670 - TGTCACTAACCGCCAAGATA D|1563|H D|1563|N S|1562|T S|1562|N SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 1.002321719672008 Q00416 0.9486550092697144 0.956179976463318 0.9512869715690612 0.9536849856376648 0.02258127182722092 0.04859811440110207 0.059726152569055564 0.02120080031454563 47.51624908974492 45.0 1.0 no 9717 chrXII_998123 26282 essential YLR430W 4689 + ATCATATGTTCGACTTTATC I|1564|M silent|ATC>ATT|I|1564 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.15096528104542287 Q00416 0.9598389863967896 0.011971540749073029 40.225153019477894 30.0 1.0 no 9718 chrXII_998152 26283 essential YLR430W 4718 + CCATGATGTACTCGCAACAA H|1574|D H|1574|Y SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -0.9938964389345216 Q00416 0.9473130106925964 0.9489949941635132 0.0 0.0 45.61198755720784 45.0 1.0 no 9719 chrXII_998226 26285 essential YLR430W 4792 + TTTCTTCAATTATTCCTCTC S|1599|C S|1599|F S|1600|* S|1600|L SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.4599346946451429 Q00416 0.945252001285553 0.9294660091400146 0.9298099875450134 0.0 0.0 0.016240125522017482 43.940550840226706 30.0 1.0 no 9720 chrXII_998231 26286 essential YLR430W 4797 + TCAATTATTCCTCTCAGGTA S|1600|* S|1600|L SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.27365540843653385 Q00416 0.9298099875450134 0.016240125522017482 46.230615497864676 35.0 1.0 no 9721 chrXII_998240r 26287 essential YLR430W 4809 - CGCTTCCCTCCATACCTGAG K|1609|N silent|AAG>AAA|K|1609 silent|GGG>GGC|G|1608 silent|GGG>GGA|G|1608 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.6929616519516604 Q00416 0.9355990290641784 0.12333858013153075 58.81738083272643 60.0 1.0 no 9722 chrXII_998291 26288 essential YLR430W 4857 + CTACCACCAACTGTTCTTTC P|1621|A P|1621|S P|1621|R P|1621|L SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 0.16239991052797315 Q00416 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.0 0.0 0.0 0.0 49.542068894532406 45.0 1.0 no 9723 chrXII_998297r 26289 essential YLR430W 4866 - GCTGCACCTGAAAGAACAGT A|1629|P A|1629|T A|1628|P A|1628|T SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -0.8550412656562194 Q00416 0.9573720097541808 0.9523990154266356 0.9573720097541808 0.9523990154266356 0.0 0.0 0.02427790500223637 0.03859533369541168 47.86032273670412 50.0 1.0 no 9724 chrXII_998452 26296 essential YLR430W 5018 + ACTAAAAGACGGCCCTGGTA L|1674|V silent|CTA>TTA|L|1674 SEN1 Splicing ENdonuclease 2231.0 0 0 0 0 -0.9556541833252392 Q00416 0.9512209892272948 0.0 48.796811897146036 50.0 1.0 no 9725 chrXII_1006484 26301 high_effect YLR435W 106 + TTTCCATGGTTATTTATAAG S|37|C S|37|F silent|TCC>TCG|S|37 silent|TCC>TCT|S|37 TSR2 Twenty S rRNA accumulation 205.0 0 0 0 0 -0.7905673997062945 Q06672 0.11093311011791228 0.03349313884973526 38.390922327095105 25.0 1.0 no 9726 chrXII_1006546r 26303 high_effect YLR435W 171 - TCTCTCTTCTCAGCTGAGTC R|63|T R|63|K D|64|H D|64|N TSR2 Twenty S rRNA accumulation 205.0 0 0 0 0 -0.8143107852393316 Q06672 0.0 0.0 0.0062316060066223145 0.018917245790362358 54.95680286069575 50.0 1.0 no 9727 chrXII_1006523r 26304 high_effect YLR435W 148 - ACCACCCCAACTGTTTTCTA G|56|R G|56|S G|56|A G|56|D TSR2 Twenty S rRNA accumulation 205.0 0 0 0 0 -2.782918042105601 Q06672 0.0 0.0 0.0 0.0 53.94295216004065 45.0 1.0 yes 9728 chrXII_1006622r 26306 high_effect YLR435W 247 - TAACGTTTCTTCGATTAAAG silent|ACG>ACC|T|88 silent|ACG>ACA|T|88 TSR2 Twenty S rRNA accumulation 205.0 0 0 0 0 1.223211443170408 Q06672 35.78602469119528 30.0 1.0 no 9729 chrXII_1006737 26310 high_effect YLR435W 359 + TTTCAATTTAAATTATAATA F|121|L silent|TTC>TTT|F|121 TSR2 Twenty S rRNA accumulation 205.0 0 0 0 0 0.3613829971567017 Q06672 0.3810869157314301 25.895762290212698 5.0 1.0 no 9730 chrXII_1011819r 26316 no_effect YLR437C 182 + CTCGGACGCTTCACTACAGC S|62|W S|62|L D|63|E silent|GAC>GAT|D|63 0 0 0 0 0.36290617074534415 O13577 0.9328449964523317 0.933793008327484 0.9551550149917604 0.02785445190966129 0.3757873773574829 0.9090967178344728 53.57020672646672 60.0 0.0 no 9731 chrXII_1011853r 26318 no_effect YLR437C 148 + TCGACCAGGGTTATGCATCG silent|GTC>GTG|V|50 silent|GTC>GTT|V|50 D|51|E silent|GAC>GAT|D|51 0 0 0 0 0.15378558792620434 O13577 0.9350050091743468 0.1267729103565216 52.191539549386505 55.00000000000001 0.0 no 9732 chrXII_1011849 26320 no_effect YLR437C 155 - GCGTCCTCGATGCATAACCC silent|ACG>ACC|T|58 silent|ACG>ACA|T|58 R|57|S silent|AGG>AGA|R|57 0 0 0 0 0.16048413599079422 O13577 0.9107279777526855 0.8186006546020508 56.632538487250436 60.0 0.0 no 9733 chrXII_1011891 26322 no_effect YLR437C 113 - GCATACCCACAGTCATCAAC M|44|I M|44|I G|43|A G|43|D 0 0 0 0 -0.2761574460213186 O13577 0.9756749868392944 0.9756749868392944 0.9656509757041932 0.9535760283470154 0.0 0.0 0.0 0.0 50.86181908814842 50.0 0.0 no 9734 chrXII_1016343r 26330 essential YLR440C 1332 + TTCTTCAATAATGCTTCTAA F|445|L silent|TTC>TTT|F|445 F|446|L silent|TTC>TTT|F|446 SEC39 SECretory 709.0 0 0 0 0 0.04571963654894956 Q12745 0.9387490153312684 0.9387490153312684 0.0380648635327816 0.0 1.6229599714279177 1.415719985961914 37.75023248874476 25.0 0.0 no 9735 chrXII_1016369r 26331 essential YLR440C 1306 + AACTTCTGGTGAAGTTCTTC L|437|V L|437|F L|438|V silent|CTG>TTG|L|438 SEC39 SECretory 709.0 0 0 0 0 -0.0601100726322872 Q12745 0.9512209892272948 0.9587849974632264 0.9512209892272948 0.8759926557540894 0.0942901447415352 0.0 4.042880058288573 6.725319862365723 4.540619850158691 44.52119781030342 40.0 0.0 no 9736 chrXII_1016380 26332 essential YLR440C 1298 - TCACCAGAAGTTCATATATT V|439|L V|439|M silent|GTG>GTC|V|439 silent|GTG>GTA|V|439 SEC39 SECretory 709.0 0 0 0 0 0.17279241271512785 Q12745 0.9539830088615416 0.9587630033493042 0.6030285358428955 0.15128910541534424 -0.7319599986076355 0.09012000262737274 41.09846591790887 30.0 0.0 no 9737 chrXII_1016491 26333 essential YLR440C 1187 - GCTTTTCATCCATACTAATT K|402|N silent|AAG>AAA|K|402 E|401|Q E|401|K SEC39 SECretory 709.0 0 0 0 0 0.2388174522730047 Q12745 0.9355990290641784 0.956179976463318 0.9475290179252625 0.061737887561321265 0.5176213979721069 1.0 4.429739952087402 0.3117800056934357 0.5061600208282471 43.794541112912434 30.0 0.0 no 9738 chrXII_1016587 26336 essential YLR440C 1091 - TGGCTTTGTTAAATTCTTCA A|370|P A|370|T SEC39 SECretory 709.0 0 0 0 0 0.7823318572607999 Q12745 0.9573720097541808 0.9523990154266356 0.28807133436203003 0.6226851344108582 6.041739940643311 0.923139989376068 42.36151060820271 30.0 0.0 no 9739 chrXII_1016751 26337 essential YLR440C 927 - TCTTCTATTGTAATTTCATC E|316|Q E|316|K E|315|Q E|315|K SEC39 SECretory 709.0 0 0 0 0 0.33797485910913705 Q12745 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.4171687662601471 0.5891491770744324 0.33453112840652466 0.4640990197658539 -0.03821999952197075 -0.19808000326156616 -0.1891999989748001 0.10707999765872957 38.59038071026265 25.0 0.0 no 9740 chrXII_1016752 26338 essential YLR440C 926 - CTTCTATTGTAATTTCATCA E|315|Q E|315|K SEC39 SECretory 709.0 0 0 0 0 0.4332278272939051 Q12745 0.956179976463318 0.9475290179252625 0.33453112840652466 0.4640990197658539 -0.1891999989748001 0.10707999765872957 39.115423685408594 25.0 0.0 no 9741 chrXII_1017018 26340 essential YLR440C 660 - TTCTTCCCATAAGACAAAGT K|226|N silent|AAG>AAA|K|226 silent|GGG>GGC|G|225 silent|GGG>GGA|G|225 SEC39 SECretory 709.0 0 0 0 0 0.07683727106715321 Q12745 0.9355990290641784 1.0 1.1229599714279177 43.08490594804573 35.0 0.0 no 9742 chrXII_1017023r 26341 essential YLR440C 652 + TAGCTCCCACTTTGTCTTAT A|219|G A|219|V P|220|A P|220|S SEC39 SECretory 709.0 0 0 0 0 0.4175080683595398 Q12745 0.9484469890594482 0.9504740238189696 0.9562489986419678 0.9498909711837769 0.01887157000601292 0.4053290784358978 0.09676097333431244 0.2401671856641769 1.0721999406814575 -0.7539200186729431 1.6927000284194946 2.612839937210083 52.389774316785186 40.0 0.0 no 9743 chrXII_1017111 26342 essential YLR440C 567 - ATCTTAAATAACTCGCTATC K|195|N silent|AAG>AAA|K|195 SEC39 SECretory 709.0 0 0 0 0 0.7965709550367547 Q12745 0.9355990290641784 0.18159860372543332 0.9660599827766418 37.29615487724203 30.0 0.0 no 9744 chrXII_1017143r 26343 essential YLR440C 532 + TCATATTTAAAATCAACGAA silent|CTC>CTG|L|178 silent|CTC>CTT|L|178 SEC39 SECretory 709.0 0 0 0 0 0.2663141760652287 Q12745 30.48360866168832 20.0 0.0 no 9745 chrXII_1017214r 26348 essential YLR440C 461 + ATCTACAAAATTTATAGGAT S|155|C S|155|F T|156|R T|156|I SEC39 SECretory 709.0 0 0 0 0 -0.5383966791423864 Q12745 0.945252001285553 0.9294660091400146 0.9476869702339172 0.9472420215606691 0.04138333722949028 0.05153372138738632 0.4878625571727753 0.17456771433353424 2.475559949874878 2.526119947433472 -0.04114000126719475 -0.4528200030326843 32.29844856673435 20.0 0.0 no 9746 chrXII_1017483 26349 essential YLR440C 195 - TCGGTTGTTTCTTCCCCTTC D|72|H D|72|N SEC39 SECretory 709.0 0 0 0 0 0.6101828606302626 Q12745 0.9486550092697144 0.956179976463318 0.08333607017993927 0.3167493045330048 58.88287706343994 50.0 0.0 no 9747 chrXII_1027096 26352 high_effect YLR447C 778 - TCTAACTCCTTCGAAATCTT R|266|T R|266|K V|265|L V|265|I VMA6 Vacuolar Membrane Atpase 345.0 0 0 0 0 0.6059064453488603 P32366 0.932735025882721 0.955805003643036 0.9539830088615416 0.9574310183525084 0.2796133160591125 1.0 0.21695154905319214 0.2901368737220764 42.65647071389896 35.0 0.0 no 9748 chrXII_1027103r 26353 high_effect YLR447C 768 + GCGCAAGCCCAAGATTTCGA Q|258|E Q|258|* A|257|G A|257|V VMA6 Vacuolar Membrane Atpase 345.0 0 0 0 0 0.2529643724109626 P32366 0.9590039849281312 0.9484469890594482 0.9504740238189696 1.0 0.03525503724813461 0.11574748903512955 52.99952858338821 55.00000000000001 0.0 no 9749 chrXII_1027124 26354 high_effect YLR447C 750 - GCCAAGTGAAACGTTGCAAG L|256|F silent|TTG>TTA|L|256 A|257|P A|257|T VMA6 Vacuolar Membrane Atpase 345.0 0 0 0 0 0.4502956091523477 P32366 0.9587849974632264 0.9573720097541808 0.9523990154266356 0.0 0.019498789682984352 0.02674981951713562 45.15921785274857 50.0 0.0 no 9750 chrXII_1027125 26355 high_effect YLR447C 749 - CCAAGTGAAACGTTGCAAGA L|256|F silent|TTG>TTA|L|256 VMA6 Vacuolar Membrane Atpase 345.0 0 0 0 0 -0.8576411377478885 P32366 0.9587849974632264 0.0 42.95358392169226 45.0 0.0 no 9751 chrXII_1027169 26357 high_effect YLR447C 705 - AACAAGTCACTTTTCAAATC L|241|F silent|TTG>TTA|L|241 VMA6 Vacuolar Membrane Atpase 345.0 0 0 0 0 0.9181526094143432 P32366 0.9587849974632264 0.07036537677049637 36.297860112206756 30.0 0.0 no 9752 chrXII_1027170 26358 high_effect YLR447C 704 - ACAAGTCACTTTTCAAATCT L|241|F silent|TTG>TTA|L|241 D|240|H D|240|N VMA6 Vacuolar Membrane Atpase 345.0 0 0 0 0 0.40689655202466907 P32366 0.9587849974632264 0.9486550092697144 0.956179976463318 0.07036537677049637 0.019415387883782387 0.22434647381305692 39.433299868062704 30.0 0.0 no 9753 chrXII_1027271 26359 high_effect YLR447C 603 - ATACATTCTTTAGCAGGTTC C|207|S C|207|Y VMA6 Vacuolar Membrane Atpase 345.0 0 0 0 0 -0.20084011475490496 P32366 0.9421560168266296 0.9290120005607604 0.14234092831611633 0.046415604650974274 44.724739380489034 35.0 0.0 no 9754 chrXII_1027383r 26360 high_effect YLR447C 488 + AAACTGTTTTGACACGGCAG N|164|K silent|AAC>AAT|N|164 VMA6 Vacuolar Membrane Atpase 345.0 0 0 0 0 -0.17107978477236013 P32366 0.9439849853515624 0.6906147599220276 43.857087181590884 45.0 0.0 no 9755 chrXII_1027389r 26361 high_effect YLR447C 482 + CTTCAAAAACTGTTTTGACA F|162|L silent|TTC>TTT|F|162 VMA6 Vacuolar Membrane Atpase 345.0 0 0 0 0 -0.0954092764483666 P32366 0.9387490153312684 0.01684507355093956 36.56878751179363 30.0 0.0 no 9756 chrXII_1027431 26363 high_effect YLR447C 443 - CCACCAATACGGTTTCGTAT V|154|L V|154|M silent|GTG>GTC|V|154 silent|GTG>GTA|V|154 VMA6 Vacuolar Membrane Atpase 345.0 0 0 0 0 -0.5395079266266154 P32366 0.9539830088615416 0.9587630033493042 0.02004414051771164 0.003683255752548576 48.82313417296513 45.0 0.0 no 9757 chrXII_1027463 26365 high_effect YLR447C 411 - TCAGTAGCAACACTCAACGT D|144|H D|144|N VMA6 Vacuolar Membrane Atpase 345.0 0 0 0 0 0.4674780159525582 P32366 0.9486550092697144 0.956179976463318 0.06113206595182419 1.0 46.045702171785145 45.0 0.0 no 9758 chrXII_1027498r 26366 high_effect YLR447C 373 + AACGTTGTCATCCGCTAGGT R|126|G R|126|C VMA6 Vacuolar Membrane Atpase 345.0 0 0 0 0 0.4147519051344295 P32366 0.8994590044021606 0.8926740288734436 0.010553927160799505 0.0014282482443377376 52.8160443662677 50.0 0.0 no 9759 chrXII_1027592r 26368 high_effect YLR447C 279 + TTCATGGACTATATCACTTA F|94|L silent|TTC>TTT|F|94 VMA6 Vacuolar Membrane Atpase 345.0 0 0 0 0 -0.5540362486431585 P32366 0.9387490153312684 0.0 40.680053879930256 30.0 0.0 no 9760 chrXII_1027612 26369 high_effect YLR447C 262 - GAACTTTCTCGTGGATCCAC K|93|N silent|AAG>AAA|K|93 VMA6 Vacuolar Membrane Atpase 345.0 0 0 0 0 0.1597447564136567 P32366 0.9355990290641784 0.19763924181461331 49.40874420881085 50.0 0.0 no 9761 chrXII_1027641 26370 high_effect YLR447C 233 - CTCTTATGTAGTTGAATTCG R|84|T R|84|K VMA6 Vacuolar Membrane Atpase 345.0 0 0 0 0 -0.3845358374542932 P32366 0.932735025882721 0.955805003643036 0.12802739441394806 0.7941134572029114 40.426811383759066 35.0 0.0 no 9762 chrXII_1027696 26371 high_effect YLR447C 178 - TGACGTGGTCAAAGACTCTG silent|ACG>ACC|T|65 silent|ACG>ACA|T|65 VMA6 Vacuolar Membrane Atpase 345.0 0 0 0 0 -1.6230298654190678 P32366 45.125457982621135 50.0 0.0 no 9763 chrXII_1056360 26373 essential YLR457C 392 - TCTTAAAGGCATCACTCCTT K|137|N silent|AAG>AAA|K|137 0 0 0 0 0.5547150713137509 P52919 0.02555188536643982 47.59803012379615 40.0 0.0 no 9764 chrXII_1056373 26374 essential YLR457C 379 - ACTCCTTAGGATCCTAGATT R|132|S silent|AGG>AGA|R|132 S|133|T S|133|N 0 0 0 0 -0.5559568527186629 P52919 0.0 0.0 0.0 49.302570443553456 40.0 0.0 no 9765 chrXII_1056385r 26376 essential YLR457C 364 + ACACAGATACAGCCAAATCT T|123|R T|123|I D|122|E silent|GAC>GAT|D|122 0 0 0 0 0.6858260494408072 P52919 0.7954579591751099 0.18293531239032745 1.0 43.87449787083625 40.0 0.0 no 9766 chrXII_1056408 26377 essential YLR457C 344 - CCATATAAGAAGGTCTTCCC M|121|I M|121|I 0 0 0 0 -1.2021981207185366 P52919 0.19522738456726074 0.19522738456726074 48.11842966536102 45.0 0.0 no 9767 chrXII_1056529 26379 essential YLR457C 223 - TATCTTTGTTAACCTTCGTT K|80|N silent|AAG>AAA|K|80 0 0 0 0 0.35607834189684995 P52919 0.4670072495937347 44.06098457336713 30.0 0.0 no 9768 chrXII_1056646 26380 essential YLR457C 106 - CTGCTTTCTTCTGCTCCTTA K|41|N silent|AAG>AAA|K|41 0 0 0 0 -3.5790845913706706 P52919 0.25480544567108154 55.515110894640095 45.0 0.0 yes 9769 chrXII_1056672 26381 essential YLR457C 80 - ATCGTTTTCTCACTTCATCA R|33|P R|33|Q 0 0 0 0 -2.27947293725068 P52919 0.0 0.0 47.11515509527794 35.0 0.0 yes 9770 chrXII_1056739 26382 essential YLR457C 13 - ATCTTTCCACAGTCCCTGTA D|11|H D|11|N W|9|C W|9|* 0 0 0 0 -0.09898268219353236 P52919 0.12478267401456833 0.6428314447402954 0.1664651334285736 56.04707339436123 45.0 0.0 no 9771 chrXII_1057403r 26384 essential YLR459W 72 - TCCAGTTGTTGTTGTAGAGA silent|CTG>CTC|L|30 silent|CTG>CTA|L|30 D|31|H D|31|N 0 0 0 0 0.3219286603802576 P41733 0.9486550092697144 0.956179976463318 0.03775505349040032 0.185244545340538 48.70594841610647 40.0 1.0 no 9772 chrXII_1057453 26385 essential YLR459W 119 + AACTTCATTTAGGTCACTAC T|41|S T|41|I S|42|* S|42|L 0 0 0 0 0.6133287642013834 P41733 0.9491789937019348 0.9472420215606691 0.9298099875450134 0.24459709227085116 0.009783601388335228 0.0 41.79946365429663 35.0 1.0 no 9773 chrXII_1057500 26388 essential YLR459W 166 + ACATCCAAGTATATAATCAT N|56|K silent|AAC>AAT|N|56 I|57|M silent|ATC>ATT|I|57 0 0 0 0 0.708375467651766 P41733 0.9439849853515624 0.9598389863967896 0.4886648058891296 0.2624498307704925 37.45036610890037 25.0 1.0 no 9774 chrXII_1057589 26393 essential YLR459W 255 + CTCATATACGCTTTAATTGA silent|CTC>CTG|L|86 silent|CTC>CTT|L|86 0 0 0 0 0.03858752377066418 P41733 39.47742120266064 30.0 1.0 no 9775 chrXII_1057624 26394 essential YLR459W 290 + TCAGCTGACAGAGGTAACAA Q|98|E Q|98|* L|99|V silent|CTG>TTG|L|99 0 0 0 0 -3.3140210339384115 P41733 0.9590039849281312 0.9512209892272948 0.9952126741409302 0.0 44.4360039488235 45.0 1.0 yes 9776 chrXII_1057679r 26396 essential YLR459W 348 - TTCACGGCATAAAGAAGTCC silent|GTG>GTC|V|122 silent|GTG>GTA|V|122 V|122|L V|122|M 0 0 0 0 -1.7778872123999483 P41733 0.9539830088615416 0.9587630033493042 1.0 0.20932911336421967 44.39599477215569 45.0 1.0 no 9777 chrXII_1057710 26398 essential YLR459W 376 + CCCTTTTATCGTGCATTAGT L|127|V L|127|F silent|ACC>ACG|T|126 silent|ACC>ACT|T|126 0 0 0 0 -0.17200342044218345 P41733 0.9064782857894896 0.2241957187652588 50.968609384075755 40.0 1.0 no 9778 chrXII_1057811 26400 essential YLR459W 477 + TCTGTTATGATTTCTATATC S|160|C S|160|F 0 0 0 0 0.5477705635248401 P41733 0.04605001583695412 0.03733845427632332 38.1150974600518 25.0 1.0 no 9779 chrXII_1057985 26401 essential YLR459W 651 + TCATTTTTGACACAGGTTTA S|218|* S|218|L 0 0 0 0 0.3860360329837855 P41733 0.01168146263808012 42.127036187822966 30.0 1.0 no 9780 chrXII_1058008 26402 essential YLR459W 674 + ATCTATTATAACCTTTGAGA S|226|C S|226|F 0 0 0 0 0.3478997499760907 P41733 0.11574400961399077 0.20089472830295566 38.21970001221314 25.0 1.0 no 9781 chrXII_1058207 26405 essential YLR459W 873 + ACAAAGCCATATCCCTCACT T|292|R T|292|I P|294|A P|294|S 0 0 0 0 0.40643405219499 P41733 0.32205384969711304 0.5968906879425049 0.6051139831542969 0.6536798477172852 50.91612517859568 45.0 1.0 no 9782 chrXII_1058216 26406 essential YLR459W 882 + TATCCCTCACTAGGTGACGC P|296|A P|296|S P|296|R P|296|L 0 0 0 0 -0.2359963851827335 P41733 0.0 0.0 0.0 0.0 54.68042662135485 55.00000000000001 1.0 no 9783 chrXII_1058219r 26407 essential YLR459W 888 - AAACCAGCGTCACCTAGTGA G|302|A G|302|D G|302|R G|302|S 0 0 0 0 0.3895669239534981 P41733 0.2426719814538956 0.051047205924987786 0.02289656363427639 0.2356373071670532 50.58549402199009 50.0 1.0 no 9784 chrXIII_12009r 26410 essential YML130C 1143 + TTCACCAAACAACATATTGT F|382|L silent|TTC>TTT|F|382 T|383|S T|383|I ERO1 ER Oxidation or Endoplasmic Reticulum Oxidoreductin 563.0 0 0 0 0 -0.07916910425453691 Q03103 0.9387490153312684 0.9491789937019348 0.9472420215606691 0.8029775619506836 0.7353320121765137 0.1968206018209457 -0.15984000265598294 0.5126799941062927 -0.3267999887466431 -0.24150599539279935 38.98184109965109 30.0 0.0 no 9785 chrXIII_12360 26412 essential YML130C 795 - TACATGTTTGTCACTCTATC M|271|I M|271|I ERO1 ER Oxidation or Endoplasmic Reticulum Oxidoreductin 563.0 0 0 0 0 0.5056399604637059 Q03103 0.9553959965705872 0.9553959965705872 1.0 1.0 0.8445000052452087 0.8445000052452087 43.70413644147197 35.0 0.0 no 9786 chrXIII_12471r 26415 essential YML130C 681 + TCCGGTTTCCATGCCTCTAT silent|TCC>TCG|S|228 silent|TCC>TCT|S|228 S|228|C S|228|F ERO1 ER Oxidation or Endoplasmic Reticulum Oxidoreductin 563.0 0 0 0 0 0.3701565828358696 Q03103 0.945252001285553 0.9294660091400146 0.0 0.0 -0.15394000709056854 -2.2553200721740723 58.296713401558286 50.0 0.0 no 9787 chrXIII_12922r 26424 essential YML130C 230 + TTTCTTCAAATACTTTCGGC F|78|L silent|TTC>TTT|F|78 F|79|L silent|TTC>TTT|F|79 ERO1 ER Oxidation or Endoplasmic Reticulum Oxidoreductin 563.0 0 0 0 0 -0.004536876911342636 Q03103 0.9387490153312684 0.9387490153312684 0.024313483387231827 0.0 1.2429399490356443 1.6505000591278076 0.5469220280647278 42.58554557188387 35.0 0.0 no 9788 chrXIII_17251r 26433 essential YML127W 190 - CGACTGGAACACATTAAAAT Q|69|H silent|CAG>CAA|Q|69 RSC9 Remodel the Structure of Chromatin 581.0 0 0 0 0 0.33402521773360405 Q03124 0.9317049980163574 0.5800544023513794 35.98182932712922 35.0 1.0 no 9789 chrXIII_17267r 26434 essential YML127W 206 - CCGTTTCCTTGGGTAGCGAC silent|ACG>ACC|T|75 silent|ACG>ACA|T|75 E|74|Q E|74|K RSC9 Remodel the Structure of Chromatin 581.0 0 0 0 0 -6.221121646810317 Q03124 1.0004899501800537 0.9891330003738404 0.5803747177124023 0.8985468745231628 57.25026409495877 60.0 1.0 yes 9790 chrXIII_17278r 26436 essential YML127W 217 - TACACCTCTGGCCGTTTCCT V|79|L V|79|I G|78|A G|78|D RSC9 Remodel the Structure of Chromatin 581.0 0 0 0 0 -4.101944566885503 Q03124 0.924390971660614 0.9320600032806396 0.9903749823570251 0.9780880212783812 0.4039176106452942 0.6118864417076111 0.0 0.0 59.85895878813454 55.00000000000001 1.0 yes 9791 chrXIII_17277r 26437 essential YML127W 216 - ACACCTCTGGCCGTTTCCTT G|78|A G|78|D V|79|L V|79|I RSC9 Remodel the Structure of Chromatin 581.0 0 0 0 0 -6.540941891437467 Q03124 0.9903749823570251 0.9780880212783812 0.924390971660614 0.9320600032806396 0.0 0.0 0.4039176106452942 0.6118864417076111 60.69581891040707 55.00000000000001 1.0 yes 9792 chrXIII_17290r 26438 essential YML127W 229 - CGTCAAATCGTCTACACCTC L|82|F silent|TTG>TTA|L|82 RSC9 Remodel the Structure of Chromatin 581.0 0 0 0 0 -2.13545554247762 Q03124 0.9341800212860109 0.12430855631828308 47.91365334171644 50.0 1.0 yes 9793 chrXIII_17405 26440 essential YML127W 341 + GATCAGCTTACGGACATTGC I|115|M silent|ATC>ATT|I|115 S|116|R silent|AGC>AGT|S|116 RSC9 Remodel the Structure of Chromatin 581.0 0 1 0 0 -0.05088091437700254 Q03124 0.9338020086288452 0.9058769941329956 0.04757138341665268 0.3614299297332764 48.91425054146777 50.0 1.0 no 9794 chrXIII_17460r 26441 essential YML127W 399 - CCTTCCACGATGCGCTCCAA G|140|R G|140|S E|139|Q E|139|K RSC9 Remodel the Structure of Chromatin 581.0 0 0 0 0 -4.723786237819146 Q03124 0.9433090090751648 0.9614629745483398 0.9840490221977234 0.972000002861023 0.5416257977485657 0.7325371503829956 0.5838308930397034 0.919764757156372 57.601638053842066 60.0 1.0 yes 9795 chrXIII_17492 26442 essential YML127W 428 + ATCGTCTATATGTGATTCAA S|144|W S|144|L S|145|C S|145|F RSC9 Remodel the Structure of Chromatin 581.0 0 0 0 0 0.5953278171700083 Q03124 0.8882390260696411 0.8951669931411743 0.9077129960060121 0.8902170062065125 0.0272119790315628 0.2643531858921051 0.11079291254281998 0.1713738888502121 40.33359069299843 30.0 1.0 no 9796 chrXIII_17555r 26443 essential YML127W 494 - TATCTTGAGCCAGATTCCTT D|171|H D|171|N RSC9 Remodel the Structure of Chromatin 581.0 0 0 0 0 -1.0482676669978228 Q03124 0.9899479746818542 1.0004899501800537 0.0 0.0 50.43011380629696 40.0 1.0 no 9797 chrXIII_17564 26444 essential YML127W 500 + TCTGGCTCAAGATACTGATT L|168|V silent|CTG>TTG|L|168 A|169|G A|169|V RSC9 Remodel the Structure of Chromatin 581.0 0 0 0 0 0.7179872556999879 Q03124 0.9254159927368164 0.9109870195388794 0.9102140069007874 0.34505826234817505 0.09766298532485962 1.0 45.120501823161995 40.0 1.0 no 9798 chrXIII_17582 26445 essential YML127W 518 + TTCGGTGCAGATACTAGTCA S|174|W S|174|L RSC9 Remodel the Structure of Chromatin 581.0 0 0 0 0 -0.1836411588365663 Q03124 0.8987550139427185 0.9056829810142516 0.040310710668563836 0.16167858242988584 49.12667587415325 45.0 1.0 no 9799 chrXIII_17719r 26448 essential YML127W 658 - CATCAAGTCCAGAGTATAAT L|225|F silent|TTG>TTA|L|225 RSC9 Remodel the Structure of Chromatin 581.0 0 0 0 0 -3.268534435772936 Q03124 0.9867290258407592 0.06436068564653398 41.212381697182714 35.0 1.0 yes 9800 chrXIII_17720 26450 essential YML127W 656 + CCATTATACTCTGGACTTGA H|220|D H|220|Y RSC9 Remodel the Structure of Chromatin 581.0 0 0 0 0 0.8859685440899473 Q03124 0.9107649922370912 0.9109159708023072 0.3523601293563843 0.3052777647972107 45.93314164225678 40.0 1.0 no 9801 chrXIII_17792r 26451 essential YML127W 731 - TCAAGATGGACACCAGCGTT L|250|F silent|TTG>TTA|L|250 RSC9 Remodel the Structure of Chromatin 581.0 0 0 0 0 0.11152474450890633 Q03124 0.9867290258407592 0.5161146521568298 49.76381275777681 50.0 1.0 no 9802 chrXIII_17816 26452 essential YML127W 752 + CTACACTAAGGACAGATACA Y|252|* silent|TAC>TAT|Y|252 T|253|S T|253|I RSC9 Remodel the Structure of Chromatin 581.0 0 0 0 0 -1.4301486208320702 Q03124 0.9758769869804382 0.9739249944686891 0.8850873112678528 0.08696234226226808 40.42122365883404 40.0 1.0 no 9803 chrXIII_17833 26453 essential YML127W 769 + ACATGGTTATTTCTATATTG Y|257|* silent|TAC>TAT|Y|257 RSC9 Remodel the Structure of Chromatin 581.0 0 0 0 0 0.7933252461726009 Q03124 37.79892317250028 25.0 1.0 no 9804 chrXIII_17881r 26455 essential YML127W 820 - TGCACTTTCCTCGTTAGCTT A|280|P A|280|T S|279|T S|279|N RSC9 Remodel the Structure of Chromatin 581.0 0 0 0 0 -0.007257639133669447 Q03124 0.920873999595642 0.912581980228424 0.9107310175895692 0.9147819876670836 0.06500983238220215 0.04866790398955345 0.4837319254875183 1.0 54.20114641148177 45.0 1.0 no 9805 chrXIII_17944r 26457 essential YML127W 883 - ATCGCATTCTAACAGTAAAA D|301|H D|301|N C|300|S C|300|Y RSC9 Remodel the Structure of Chromatin 581.0 0 0 0 0 -0.006450619106252463 Q03124 0.9202659726142884 0.9315000176429749 0.9456340074539183 0.9283859729766846 0.030535027384758 0.5079560875892639 1.0 0.13733996450901031 37.17959448674328 30.0 1.0 no 9806 chrXIII_17997 26458 essential YML127W 933 + CTCTATCAATACATTTTGCC silent|CTC>CTG|L|312 silent|CTC>CTT|L|312 Q|314|E Q|314|* RSC9 Remodel the Structure of Chromatin 581.0 0 0 0 0 0.5537762802920596 Q03124 0.973230004310608 0.0 43.53669588104657 35.0 1.0 no 9807 chrXIII_18032 26460 essential YML127W 968 + CACTGAGTTATTCAAGAGTA T|324|S T|324|I RSC9 Remodel the Structure of Chromatin 581.0 0 0 0 0 0.14359136555406746 Q03124 0.9758769869804382 0.9739249944686891 0.755294680595398 0.20688603818416595 40.42209684732728 35.0 1.0 no 9808 chrXIII_18189r 26462 essential YML127W 1128 - AACAGATCCTCAGATAAATT silent|CTG>CTC|L|382 silent|CTG>CTA|L|382 RSC9 Remodel the Structure of Chromatin 581.0 0 0 0 0 -1.8530300601123482 Q03124 37.91669497221238 30.0 1.0 no 9809 chrXIII_18238r 26464 essential YML127W 1177 - CAACCAAGCGGTTGACCTCA W|398|C W|398|* W|398|S W|398|* RSC9 Remodel the Structure of Chromatin 581.0 0 0 0 0 -1.9837528378403164 Q03124 0.9440850019454956 0.9438130259513856 0.0 0.0 52.16805876882717 55.00000000000001 1.0 no 9810 chrXIII_19418 26470 essential YML126C 1098 - TACATGTTACCTGTGTTTGT M|372|I M|372|I ERG13 ERGosterol biosynthesis 491.0 0 0 0 0 0.4755165504255664 P54839 0.13799379765987396 0.13799379765987396 46.98925059356202 35.0 0.0 no 9811 chrXIII_19457 26471 essential YML126C 1059 - GCAACTCTCTCTTTGTGGAA A|360|P A|360|T V|359|L V|359|I ERG13 ERGosterol biosynthesis 491.0 0 0 0 0 0.2592546724533444 P54839 0.2627413868904114 0.5490201711654663 0.07996362447738647 0.05182119086384773 7.218400001525879 1.5335999727249146 48.61091979590293 45.0 0.0 no 9812 chrXIII_19629 26474 essential YML126C 887 - CCAATTTACAGGTTGGAACA L|302|F silent|TTG>TTA|L|302 ERG13 ERGosterol biosynthesis 491.0 0 1 0 0 -0.3310185018886208 P54839 0.012885697185993195 0.8424000144004822 43.710418087256066 40.0 0.0 no 9813 chrXIII_19629r 26475 essential YML126C 884 + CCATGTTCCAACCTGTAAAT H|296|D H|296|Y ERG13 ERGosterol biosynthesis 491.0 0 0 0 0 -0.10611763260788352 P54839 0.040282581001520164 0.0026334263384342194 46.62950592054239 40.0 0.0 no 9814 chrXIII_19682 26476 essential YML126C 834 - TTCAAAGCATCCGAACCAGC L|284|F silent|TTG>TTA|L|284 ERG13 ERGosterol biosynthesis 491.0 0 0 0 0 -0.10285625860899006 P54839 0.06522447615861893 0.4174000024795532 48.4553468090599 50.0 0.0 no 9815 chrXIII_19717r 26478 essential YML126C 796 + CCAAGAAGGCTATTTCTAAA silent|TCC>TCG|S|266 silent|TCC>TCT|S|266 ERG13 ERGosterol biosynthesis 491.0 0 0 0 0 -0.0006996611861466718 P54839 40.02503874598523 35.0 0.0 no 9816 chrXIII_19718r 26479 essential YML126C 795 + TCCAAGAAGGCTATTTCTAA silent|TCC>TCG|S|266 silent|TCC>TCT|S|266 S|266|C S|266|F ERG13 ERGosterol biosynthesis 491.0 0 0 0 1 0.8100349132233564 P54839 0.08219491690397263 0.08628484606742859 42.27311606126472 35.0 0.0 no 9817 chrXIII_19731r 26480 essential YML126C 782 + TTACAAGAGTTATTCCAAGA Y|262|* silent|TAC>TAT|Y|262 ERG13 ERGosterol biosynthesis 491.0 0 1 0 0 1.000050080065702 P54839 38.906663665899366 30.0 0.0 no 9818 chrXIII_19767r 26481 essential YML126C 746 + TTCATTAACTTGTTACGTCA S|250|* S|250|L ERG13 ERGosterol biosynthesis 491.0 0 0 0 0 0.496823343195695 P54839 0.0017253200057893991 41.183862537901966 30.0 0.0 no 9819 chrXIII_19796r 26482 essential YML126C 717 + AGCGAATATCCTTACGTCGA S|240|R silent|AGC>AGT|S|240 ERG13 ERGosterol biosynthesis 491.0 0 0 0 0 -0.0270751345326245 P54839 0.00213405373506248 47.056801098543595 45.0 0.0 no 9820 chrXIII_19877 26486 essential YML126C 639 - TCAAATACAATTGGAGCATC D|220|H D|220|N ERG13 ERGosterol biosynthesis 491.0 0 0 0 0 0.5610514707627445 P54839 0.0060080504044890395 0.10511648654937744 38.28553548322054 35.0 0.0 no 9821 chrXIII_19906r 26487 essential YML126C 607 + GTGCCGGTACTGTTGCTATG A|204|G A|204|V silent|GCC>GCG|A|204 silent|GCC>GCT|A|204 ERG13 ERGosterol biosynthesis 491.0 0 0 0 0 -0.9722387115714244 P54839 0.016011254861950874 0.16085930168628693 1.5490000247955322 -0.39660000801086426 54.97506269874822 55.00000000000001 0.0 no 9822 chrXIII_19912 26488 essential YML126C 604 - AGCAACAGTACCGGCACCAC A|208|P A|208|T V|207|L V|207|I ERG13 ERGosterol biosynthesis 491.0 0 0 0 0 -2.86479917857376 P54839 0.006503701210021973 0.03919821232557297 0.053343217819929116 0.3136712908744812 54.816092415562245 60.0 0.0 yes 9823 chrXIII_19942 26492 essential YML126C 574 - TGCGGCACCCTTATCGTAGA A|198|P A|198|T A|197|P A|197|T ERG13 ERGosterol biosynthesis 491.0 0 0 0 0 0.04131676562081106 P54839 0.005211039446294308 0.0040381629951298246 0.3090366721153259 0.4737052917480469 -0.6754000186920166 1.1411999464035034 -0.7730000019073486 0.1289999932050705 55.95634409041361 55.00000000000001 0.0 no 9824 chrXIII_20054r 26495 essential YML126C 459 + GACACGCTTAATGCCTGTTA D|154|E silent|GAC>GAT|D|154 T|155|R T|155|M ERG13 ERGosterol biosynthesis 491.0 0 0 0 0 -1.92530723524404 P54839 0.025884246453642845 0.00652821222320199 0.0039358893409371385 48.87467926363416 45.0 0.0 no 9825 chrXIII_20051r 26496 essential YML126C 462 + ACGCTTAATGCCTGTTACGG L|156|V L|156|F T|155|R T|155|M ERG13 ERGosterol biosynthesis 491.0 0 1 0 0 0.4669891304527065 P54839 1.0 0.20915623009204865 0.00652821222320199 0.0039358893409371385 -0.13279999792575836 1.118000030517578 49.75066071944632 50.0 0.0 no 9826 chrXIII_20102r 26497 essential YML126C 411 + TCTGTCTTGATGCAATTGTT S|138|C S|138|F silent|GTC>GTG|V|139 silent|GTC>GTT|V|139 ERG13 ERGosterol biosynthesis 491.0 0 1 0 0 1.078309036817508 P54839 0.002419877564534545 0.0012173163704574108 45.32089750940418 35.0 0.0 no 9827 chrXIII_20167 26498 essential YML126C 349 - TTCTAATCTACCAATTTTGT E|123|Q E|123|K ERG13 ERGosterol biosynthesis 491.0 0 1 0 0 -0.2338999821604309 P54839 0.007199011743068695 0.005566272418946028 39.84968503622547 25.0 0.0 no 9828 chrXIII_20212 26500 essential YML126C 304 - CAACTTAGACAAAACAGTTA K|107|N silent|AAG>AAA|K|107 ERG13 ERGosterol biosynthesis 491.0 0 1 0 0 0.8660873329744468 P54839 0.8758646845817566 34.24321997120154 30.0 0.0 no 9829 chrXIII_20378 26503 essential YML126C 138 - CCTTTAATACCGACATTTTG G|53|R G|53|S ERG13 ERGosterol biosynthesis 491.0 0 0 0 0 0.14711884648571225 P54839 0.002607424044981599 0.017993614077568054 42.258250603309186 35.0 0.0 no 9830 chrXIII_20504r 26505 essential YML126C 9 + TCAACTAAACTTTGTTGGTG S|4|* S|4|L T|5|S T|5|I ERG13 ERGosterol biosynthesis 491.0 0 0 0 0 -0.7159075231132048 P54839 39.238444330757204 35.0 0.0 no 9831 chrXIII_21146r 26509 essential YML125C 531 + AAGCATTTAGGTATCGTAGC H|179|D H|179|Y PGA3 Processing of Gas1p and ALP 312.0 0 0 0 0 -1.2582991358210844 Q12746 0.9473130106925964 0.9489949941635132 0.3959552943706513 0.07174316048622131 45.03808100785153 40.0 0.0 no 9832 chrXIII_21182 26511 essential YML125C 498 - TCGTAGTTCAAAGTACCTAT E|173|Q E|173|K PGA3 Processing of Gas1p and ALP 312.0 0 0 0 0 0.622353450073902 Q12746 0.956179976463318 0.9475290179252625 0.5706929564476013 0.9485362768173218 43.08470159188312 35.0 0.0 no 9833 chrXIII_21338 26512 essential YML125C 342 - ACCTCTTGTTTGCCGTCAAT E|120|D silent|GAG>GAA|E|120 V|121|L V|121|I PGA3 Processing of Gas1p and ALP 312.0 0 0 0 0 0.6222445222903672 Q12746 0.94931298494339 0.9539830088615416 0.9574310183525084 0.02035888284444809 0.06725206971168518 0.22147321701049805 -0.6999599933624268 -0.3639200031757355 53.33017932106379 45.0 0.0 no 9834 chrXIII_21339r 26513 essential YML125C 338 + TCCAATTGACGGCAAACAAG P|114|R P|114|L P|114|A P|114|S PGA3 Processing of Gas1p and ALP 312.0 0 0 0 0 0.5670319086433424 Q12746 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.4970641434192658 0.2869623899459839 0.729278564453125 0.6956658959388733 41.97713287364661 45.0 0.0 no 9835 chrXIII_21367 26515 essential YML125C 313 - TACAGCAACATGATGACCAG V|111|L V|111|I A|110|P A|110|T PGA3 Processing of Gas1p and ALP 312.0 0 0 0 0 -0.34676858208022365 Q12746 0.9539830088615416 0.9574310183525084 0.9573720097541808 0.9523990154266356 0.3507910370826721 0.7382328510284424 0.0495598204433918 0.3342802822589874 4.618720054626465 3.1094601154327397 43.80146466458343 45.0 0.0 no 9836 chrXIII_21414 26516 essential YML125C 266 - TCTTCAACTTAAAACGATAC K|95|N silent|AAG>AAA|K|95 L|94|F silent|TTG>TTA|L|94 PGA3 Processing of Gas1p and ALP 312.0 0 0 0 0 0.5340003629011911 Q12746 0.9355990290641784 0.9587849974632264 0.21750766038894653 0.0 0.8789200186729431 3.511759996414185 34.2501891553797 30.0 0.0 no 9837 chrXIII_21473 26520 essential YML125C 207 - TCTAACGAAGTCCACCTATC E|76|Q E|76|K silent|TCG>TCC|S|74 silent|TCG>TCA|S|74 PGA3 Processing of Gas1p and ALP 312.0 0 0 0 0 -0.4452772202377042 Q12746 0.956179976463318 0.9475290179252625 0.2189128398895264 0.22118042409420013 46.506915565749814 45.0 0.0 no 9838 chrXIII_21587r 26522 essential YML125C 90 + GCAATCACCACGTATATGTC A|31|G A|31|V I|32|M silent|ATC>ATT|I|32 PGA3 Processing of Gas1p and ALP 312.0 0 0 0 0 -0.08261157537536165 Q12746 0.9484469890594482 0.9504740238189696 0.9598389863967896 0.328665554523468 0.5395918488502502 0.05594906210899353 47.10981363894689 45.0 0.0 no 9839 chrXIII_21614r 26525 essential YML125C 63 + CCTGCCGCGCTATTCGTTGT P|22|R P|22|L A|23|G A|23|V PGA3 Processing of Gas1p and ALP 312.0 0 0 0 0 -1.346432856962115 Q12746 0.9432820081710817 0.9430609941482544 0.9484469890594482 0.9504740238189696 0.0 0.0 0.3562581539154053 0.9813820719718932 60.058293800106185 60.0 0.0 no 9840 chrXIII_21647r 26526 essential YML125C 30 + ATTCTAGACGAACCTGTCCA L|12|V silent|CTA>TTA|L|12 PGA3 Processing of Gas1p and ALP 312.0 0 0 0 0 0.5967714967546938 Q12746 0.9512209892272948 0.3320634961128235 48.98078358025674 45.0 0.0 no 9841 chrXIII_42469r 26528 essential YML114C 1084 + GAGCAAAATCGCTAAAACGT A|363|G A|363|V TAF8 TATA binding protein-Associated Factor 510.0 0 0 0 0 -0.2255008345082303 Q03750 0.9484469890594482 0.9504740238189696 0.12479928135871887 0.08065404742956161 38.67732049390384 40.0 0.0 no 9842 chrXIII_42521 26529 essential YML114C 1035 - TTCTTCAACTTCTGGACCTT K|351|N silent|AAG>AAA|K|351 L|350|F silent|TTG>TTA|L|350 TAF8 TATA binding protein-Associated Factor 510.0 0 0 0 0 -0.023894228848241945 Q03750 0.9355990290641784 0.9587849974632264 0.03010978363454342 0.1324889212846756 48.73711213077939 40.0 0.0 no 9843 chrXIII_42858r 26539 essential YML114C 695 + GTCAAATACCCCGCAACCGC S|233|* S|233|L TAF8 TATA binding protein-Associated Factor 510.0 0 1 0 0 -0.7708010400330312 Q03750 0.9298099875450134 0.2522849142551422 54.5056017505338 60.0 0.0 no 9844 chrXIII_43046 26542 essential YML114C 510 - CTCGGTATCTGTTTTTCCAG silent|CCG>CCC|P|176 silent|CCG>CCA|P|176 TAF8 TATA binding protein-Associated Factor 510.0 0 0 0 0 0.1299219032865826 Q03750 50.47348166969368 45.0 0.0 no 9845 chrXIII_43047 26543 essential YML114C 509 - TCGGTATCTGTTTTTCCAGT silent|CCG>CCC|P|176 silent|CCG>CCA|P|176 TAF8 TATA binding protein-Associated Factor 510.0 0 0 0 0 1.0369961995388275 Q03750 51.371111280580074 40.0 0.0 no 9846 chrXIII_43110r 26544 essential YML114C 443 + GGACGAATTGAATAATATCG D|149|E silent|GAC>GAT|D|149 TAF8 TATA binding protein-Associated Factor 510.0 0 0 0 0 0.5807350780058241 Q03750 0.9532920122146606 0.6834195852279663 35.069060386236345 35.0 0.0 no 9847 chrXIII_43062r 26545 essential YML114C 491 + GCTGCCTCCCTCTAACCCAC L|165|V silent|CTG>TTG|L|165 P|166|A P|166|S TAF8 TATA binding protein-Associated Factor 510.0 0 0 0 0 -0.6540689738894212 Q03750 0.9512209892272948 0.9562489986419678 0.9498909711837769 1.0 0.18256144225597384 0.15949906408786774 64.18288151992635 65.0 0.0 no 9848 chrXIII_43133 26546 essential YML114C 423 - TCTTCATCTTCTTCGTTATG E|148|Q E|148|K E|147|Q E|147|K TAF8 TATA binding protein-Associated Factor 510.0 0 0 0 0 0.422108797032559 Q03750 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.6301687359809875 0.8741238117218018 0.5032823085784912 1.0 45.19255454441725 35.0 0.0 no 9849 chrXIII_43180 26547 essential YML114C 376 - CATCAATTTTTCATATTCCG L|131|F silent|TTG>TTA|L|131 TAF8 TATA binding protein-Associated Factor 510.0 0 0 0 0 -0.014534947715129946 Q03750 0.9587849974632264 0.04615800455212593 40.57273006393621 30.0 0.0 no 9850 chrXIII_43207 26548 essential YML114C 349 - CTTCGATTTGATGAATTCTG silent|TCG>TCC|S|122 silent|TCG>TCA|S|122 TAF8 TATA binding protein-Associated Factor 510.0 0 0 0 0 0.5300870375644537 Q03750 39.34722131230456 35.0 0.0 no 9851 chrXIII_43197r 26549 essential YML114C 356 + CATCAAATCGAAGCATTCCA I|120|M silent|ATC>ATT|I|120 TAF8 TATA binding protein-Associated Factor 510.0 0 0 0 0 0.3972340699209956 Q03750 0.9598389863967896 0.29603904485702515 43.23254332375802 40.0 0.0 no 9852 chrXIII_43227 26550 essential YML114C 329 - AGGCCTGAAACTGCTGATAA A|116|P A|116|T Q|115|H silent|CAG>CAA|Q|115 TAF8 TATA binding protein-Associated Factor 510.0 0 0 0 0 0.3850087036454039 Q03750 0.9573720097541808 0.9523990154266356 0.9570760130882264 0.23696368932724 0.4852821826934815 0.014992908574640753 45.92559639996927 45.0 0.0 no 9853 chrXIII_43344 26551 essential YML114C 212 - TCCGAAACATGCCGTCCATT R|77|P R|77|Q silent|CGG>CGC|R|77 silent|CGG>CGA|R|77 TAF8 TATA binding protein-Associated Factor 510.0 0 0 0 0 0.479494133892015 Q03750 0.9099509716033936 0.949662983417511 0.2844218909740448 0.6041006445884705 51.864697388106954 50.0 0.0 no 9854 chrXIII_43345r 26552 essential YML114C 208 + TCCAAATGGACGGCATGTTT Q|71|E Q|71|* silent|GTC>GTG|V|70 silent|GTC>GTT|V|70 TAF8 TATA binding protein-Associated Factor 510.0 0 0 0 0 -0.17782412374502332 Q03750 0.9590039849281312 0.0 47.753696118844964 45.0 0.0 no 9855 chrXIII_43348 26553 essential YML114C 208 - AAACATGCCGTCCATTTGGA M|75|I M|75|I TAF8 TATA binding protein-Associated Factor 510.0 0 0 0 0 1.1447005203529006 Q03750 0.9553959965705872 0.9553959965705872 0.11539782583713533 0.11539782583713533 49.0275437522485 45.0 0.0 no 9856 chrXIII_43383r 26556 essential YML114C 170 + AAACTTTGCATTGGATGAGC N|58|K silent|AAC>AAT|N|58 TAF8 TATA binding protein-Associated Factor 510.0 0 0 0 0 0.7131505808326476 Q03750 0.9439849853515624 1.0 42.747559151651615 40.0 0.0 no 9857 chrXIII_43392r 26557 essential YML114C 161 + CTGCATTTCAAACTTTGCAT C|55|W silent|TGC>TGT|C|55 TAF8 TATA binding protein-Associated Factor 510.0 0 0 0 0 0.35043451604130044 Q03750 0.9286419749259948 0.0297906082123518 43.54252661594859 35.0 0.0 no 9858 chrXIII_43448 26558 essential YML114C 108 - TTCTTTAGAATTTCAACTAC K|42|N silent|AAG>AAA|K|42 TAF8 TATA binding protein-Associated Factor 510.0 0 0 0 0 0.4474349272975482 Q03750 0.9355990290641784 0.5991246700286865 35.33656927110121 25.0 0.0 no 9859 chrXIII_43487 26559 essential YML114C 69 - TGACTAATTTCCGTCAAATC S|29|T S|29|N TAF8 TATA binding protein-Associated Factor 510.0 0 0 0 0 -0.013569425190427864 Q03750 0.9512869715690612 0.9536849856376648 0.5700663924217224 0.4927062094211578 40.2164707739309 35.0 0.0 no 9860 chrXIII_45077 26562 high_effect YML112W 14 + AGCTAGATTACAATTCATTC A|6|G A|6|V CTK3 Carboxy-Terminal domain Kinase 296.0 0 1 0 0 0.3274075773824838 P46963 0.0 0.0 39.002284687088654 30.0 1.0 no 9861 chrXIII_45101r 26564 high_effect YML112W 41 - GCGTCTTTTGCAGGTTCTTC silent|ACG>ACC|T|20 silent|ACG>ACA|T|20 K|19|N silent|AAG>AAA|K|19 CTK3 Carboxy-Terminal domain Kinase 296.0 0 0 0 1 0.3105474402078451 P46963 0.0 55.483137756587105 50.0 1.0 no 9862 chrXIII_45171r 26568 high_effect YML112W 111 - TTCAGCTTTTGTTGCGATGA silent|CTG>CTC|L|43 silent|CTG>CTA|L|43 K|42|N silent|AAG>AAA|K|42 CTK3 Carboxy-Terminal domain Kinase 296.0 0 0 0 0 0.6321759564742984 P46963 0.4951406419277191 48.246822636921756 40.0 1.0 no 9863 chrXIII_45201r 26569 high_effect YML112W 141 - TTTCTCAAGTAGAACTGTAT R|53|T R|53|K L|52|F silent|TTG>TTA|L|52 CTK3 Carboxy-Terminal domain Kinase 296.0 0 0 0 0 -1.2224722298278792 P46963 0.12196207046508788 1.0 0.0 39.07632090914189 30.0 1.0 no 9864 chrXIII_45221 26570 high_effect YML112W 158 + AAACTACAGACATCACTACG N|54|K silent|AAC>AAT|N|54 Y|55|* silent|TAC>TAT|Y|55 CTK3 Carboxy-Terminal domain Kinase 296.0 0 0 0 0 0.8566042980628971 P46963 0.25265374779701233 38.810811411565226 40.0 1.0 no 9865 chrXIII_45271r 26571 high_effect YML112W 211 - ATCTAGTGGGTCCATCTTCA D|77|H D|77|N CTK3 Carboxy-Terminal domain Kinase 296.0 0 0 0 0 0.5912906537739052 P46963 0.16599079966545105 0.1450134813785553 53.736347954899365 45.0 1.0 no 9866 chrXIII_45285r 26573 high_effect YML112W 225 - ACTACGTCCAGTCTATCTAG V|82|L V|82|M V|81|L V|81|I CTK3 Carboxy-Terminal domain Kinase 296.0 0 0 0 0 -0.9176500192863388 P46963 1.0 0.2320466488599777 0.06615062803030014 0.4674490690231323 48.65482880886003 45.0 1.0 no 9867 chrXIII_45389 26574 high_effect YML112W 326 + GCTACTCATGGACATAGACT L|110|V silent|CTA>TTA|L|110 L|111|V L|111|F CTK3 Carboxy-Terminal domain Kinase 296.0 0 0 0 0 0.4832265696658965 P46963 0.0 0.0498281829059124 0.03064978308975697 47.12299667011303 45.0 1.0 no 9868 chrXIII_45565r 26582 high_effect YML112W 505 - CTCTGTCTTGACACTGTACC E|175|Q E|175|K K|173|N silent|AAG>AAA|K|173 CTK3 Carboxy-Terminal domain Kinase 296.0 0 0 0 0 0.7415507538831374 P46963 0.37731510400772095 0.4202447533607483 0.2972983419895172 51.32381978325975 50.0 1.0 no 9869 chrXIII_58075r 26587 essential YML105C 590 + AACTACTATTGAATCTTTAA T|198|S T|198|I T|199|S T|199|I SEC65 SECretory 273.0 0 0 0 0 0.9029736487163544 P29478 0.9491789937019348 0.9472420215606691 0.9491789937019348 0.9472420215606691 0.0 0.0 0.09536948055028917 0.01607033610343933 32.79631220820147 20.0 0.0 no 9870 chrXIII_58076r 26588 essential YML105C 589 + CAACTACTATTGAATCTTTA T|198|S T|198|I T|199|S T|199|I SEC65 SECretory 273.0 0 0 0 0 0.1338690568244108 P29478 0.9491789937019348 0.9472420215606691 0.9491789937019348 0.9472420215606691 0.0 0.0 0.09536948055028917 0.01607033610343933 35.380316886082774 25.0 0.0 no 9871 chrXIII_58119r 26590 essential YML105C 546 + AGGCAATTAATGAAAGCTGT Q|184|E Q|184|* SEC65 SECretory 273.0 0 0 0 0 1.0443928897566632 P29478 0.9590039849281312 1.0 39.767363301199104 35.0 0.0 no 9872 chrXIII_58212 26591 essential YML105C 456 - CCAGGATTACCAAAATCTTG G|159|R G|159|S SEC65 SECretory 273.0 0 0 0 0 0.4946198713749757 P29478 0.941340982913971 0.951104998588562 0.0 0.0 42.07842833956721 40.0 0.0 no 9873 chrXIII_58212r 26592 essential YML105C 453 + CCACAAGATTTTGGTAATCC Q|153|E Q|153|* P|152|R P|152|L SEC65 SECretory 273.0 0 0 0 0 -0.39105675956456776 P29478 0.9590039849281312 0.9432820081710817 0.9430609941482544 0.06991352140903473 0.0 0.0 44.34343595412776 40.0 0.0 no 9874 chrXIII_58258 26593 essential YML105C 410 - TGCATAATATTCCCAATTCA C|143|S C|143|Y SEC65 SECretory 273.0 0 0 0 0 0.14623723364171473 P29478 0.9421560168266296 0.9290120005607604 0.07173508405685425 0.031596090644598014 42.920016838150616 30.0 0.0 no 9875 chrXIII_58441 26600 essential YML105C 227 - GTTCAACCTTACCAGTTTTT E|82|Q E|82|K V|81|L V|81|I SEC65 SECretory 273.0 0 0 0 0 0.4244827736537171 P29478 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.25006604194641113 0.37223151326179504 0.8350644707679749 0.9549439549446106 47.909146632123566 35.0 0.0 no 9876 chrXIII_58512 26602 essential YML105C 156 - TTACTGTTGTTATTCGTGCC S|58|T S|58|N SEC65 SECretory 273.0 0 1 0 0 -0.21711472487996625 P29478 0.9512869715690612 0.9536849856376648 0.6696924567222595 0.5288233757019043 48.86001913588689 40.0 0.0 no 9877 chrXIII_58557 26603 essential YML105C 111 - TCCTGGCTCCTTACAACCTT Q|43|H silent|CAG>CAA|Q|43 D|44|H D|44|N SEC65 SECretory 273.0 0 0 0 0 -1.795518040570664 P29478 0.9570760130882264 0.9486550092697144 0.956179976463318 0.11866646260023116 0.14330382645130155 0.38387754559516907 56.45597554884694 50.0 0.0 no 9878 chrXIII_58568 26605 essential YML105C 100 - TACAACCTTAGGCGTTATCT V|40|L V|40|I V|39|L V|39|I SEC65 SECretory 273.0 0 1 0 0 -2.638937134476224 P29478 0.9539830088615416 0.9574310183525084 0.9539830088615416 0.9574310183525084 0.19641776382923126 0.14582206308841705 0.4505390822887421 0.479583740234375 47.0555699170215 40.0 0.0 yes 9879 chrXIII_58593 26609 essential YML105C 75 - GCGATCGGCGTCCTCAAAGA A|32|P A|32|T silent|CCG>CCC|P|30 silent|CCG>CCA|P|30 SEC65 SECretory 273.0 0 1 0 0 0.4349222736257233 P29478 0.9573720097541808 0.9523990154266356 0.12415003776550293 0.22074201703071594 53.61539868010829 60.0 0.0 no 9880 chrXIII_58604r 26611 essential YML105C 61 + CCGAGTTAGATCCATCTTTG silent|GCC>GCG|A|21 silent|GCC>GCT|A|21 SEC65 SECretory 273.0 0 0 0 0 0.5511306660478154 P29478 48.506229709577845 45.0 0.0 no 9881 chrXIII_58621 26612 essential YML105C 47 - ACTCGGCCAATTCCATATCA E|22|Q E|22|K E|22|D silent|GAG>GAA|E|22 SEC65 SECretory 273.0 0 0 0 0 -0.2643810212071848 P29478 0.956179976463318 0.9475290179252625 0.94931298494339 0.2289467751979828 0.11049111932516098 0.3704586923122406 51.16646137766634 45.0 0.0 no 9882 chrXIII_77348r 26615 essential YML098W 84 - CACTGCACAGTAGCTTGTAG Q|34|H silent|CAG>CAA|Q|34 silent|GTG>GTC|V|33 silent|GTG>GTA|V|33 TAF13 TATA binding protein-Associated Factor 167.0 0 0 0 0 -1.7082521599076317 P11747 0.9570760130882264 0.11124099791049956 49.71961529560185 50.0 1.0 no 9883 chrXIII_77431r 26619 essential YML098W 167 - GCTTATTGCGCTGAGAATTC K|62|N silent|AAG>AAA|K|62 TAF13 TATA binding protein-Associated Factor 167.0 0 0 0 0 -0.4916957157400156 P11747 0.9355990290641784 0.0 47.191697941596146 45.0 1.0 no 9884 chrXIII_77440 26620 essential YML098W 173 + TCAGCGCAATAAGCTCCGAT Q|59|E Q|59|* R|60|G R|60|C TAF13 TATA binding protein-Associated Factor 167.0 0 0 0 0 -2.996086011366684 P11747 0.9590039849281312 0.8994590044021606 0.8926740288734436 0.7063115835189819 0.006691921502351761 0.0008873669430613518 50.152811382494114 50.0 1.0 yes 9885 chrXIII_77574 26622 essential YML098W 307 + ACAATCAAAATTCATTAAAG D|103|E silent|GAC>GAT|D|103 Q|105|E Q|105|* TAF13 TATA binding protein-Associated Factor 167.0 0 0 0 0 -0.2794912639461787 P11747 0.9532920122146606 0.9590039849281312 0.6295225024223328 0.06846966594457626 28.457054869151197 20.0 1.0 no 9886 chrXIII_86233 26625 essential YML092C 487 - CACAGAACCTTTTCCTATAG V|169|L V|169|M PRE8 PRoteinase yscE 250.0 0 1 0 0 -0.30096551019092616 P23639 0.9539830088615416 0.9587630033493042 0.2735288739204407 0.09710359573364258 -0.11444000154733658 -0.017619999125599858 -0.2789599895477295 -0.3639200031757355 44.53945676028161 40.0 0.0 no 9887 chrXIII_86263r 26628 essential YML092C 454 + CTTCCGGTTCCTACTTCCCT S|153|C S|153|F silent|TCC>TCG|S|153 silent|TCC>TCT|S|153 PRE8 PRoteinase yscE 250.0 0 0 0 0 -0.6596572438876965 P23639 0.945252001285553 0.9294660091400146 0.0013027290115132928 0.0005649763043038548 0.7118399739265442 0.09611999988555907 61.407223561823464 55.00000000000001 0.0 no 9888 chrXIII_86332 26630 essential YML092C 388 - AATCAACAGTGAAACACCAA L|135|F silent|TTG>TTA|L|135 silent|CTG>CTC|L|134 silent|CTG>CTA|L|134 PRE8 PRoteinase yscE 250.0 0 0 0 0 0.8161376861009481 P23639 0.9587849974632264 0.036286041140556335 3.1880199909210205 37.67481992109344 35.0 0.0 no 9889 chrXIII_86347 26631 essential YML092C 373 - ACCAAAGGGTCTGACACCAC G|131|R G|131|S G|131|A G|131|D PRE8 PRoteinase yscE 250.0 0 0 0 0 -1.1848571169988678 P23639 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 -0.9535199999809264 0.35392001271247864 -0.3777399957180023 1.0023800134658811 50.685248943520314 55.00000000000001 0.0 no 9890 chrXIII_86398 26633 essential YML092C 322 - TACTTCAGAAACCAGTAATT V|114|L V|114|I E|113|Q E|113|K PRE8 PRoteinase yscE 250.0 0 1 0 0 -0.3355043650305146 P23639 0.9539830088615416 0.9574310183525084 0.956179976463318 0.9475290179252625 0.2662501037120819 1.0 0.5039626359939575 0.6608081459999084 -0.8607199788093567 -0.926859974861145 -0.7760599851608276 -1.1529799699783323 38.32886793634185 30.0 0.0 no 9891 chrXIII_86480 26635 essential YML092C 240 - TCCACTAAAACTCTATAATC silent|GTG>GTC|V|86 silent|GTG>GTA|V|86 D|87|H D|87|N PRE8 PRoteinase yscE 250.0 0 0 0 1 -1.0138078986864894 P23639 0.9486550092697144 0.956179976463318 0.14842799305915833 0.7080915570259094 0.17642000317573547 0.3799000084400177 0.3095099925994873 0.1425900012254715 36.41092004981493 30.0 0.0 no 9892 chrXIII_86491 26637 essential YML092C 229 - TCTATAATCAGGCCCCATAC R|83|T R|83|K PRE8 PRoteinase yscE 250.0 0 0 0 0 -1.0061751880650098 P23639 0.932735025882721 0.955805003643036 0.0022203889675438404 0.05944712087512016 0.04520000144839287 -0.2194799929857254 50.37090636944208 45.0 0.0 no 9893 chrXIII_86525r 26641 essential YML092C 192 + TCCTTACTAACACCGGACAT silent|TCC>TCG|S|65 silent|TCC>TCT|S|65 S|65|C S|65|F PRE8 PRoteinase yscE 250.0 0 0 0 0 0.7433931033523928 P23639 0.945252001285553 0.9294660091400146 0.07840795069932938 0.048026610165834434 -1.2641799449920654 -2.049000024795532 48.126577823360044 45.0 0.0 no 9894 chrXIII_86633r 26644 essential YML092C 84 + AAACAAGGTGTCACCTCATT Q|30|E Q|30|* PRE8 PRoteinase yscE 250.0 0 1 0 0 1.1787514628259892 P23639 0.9590039849281312 0.7118868231773376 0.9163600206375122 0.013399999588727951 44.87174474392469 40.0 0.0 no 9895 chrXIII_86647 26645 essential YML092C 73 - ACCTTGTTTTACTGCCGTCA G|31|R G|31|S G|31|A G|31|D PRE8 PRoteinase yscE 250.0 0 1 0 0 0.2298199368187533 P23639 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 11.04994010925293 3.3171999454498287 2.075939893722534 10.283459663391113 6.634109973907472 0.8267199993133545 1.1309800148010254 3.3485300540924072 54.151892391025676 45.0 0.0 no 9896 chrXIII_88072 26648 essential YML091C 2640 - GCAATACTTTTGAACTTTTC A|887|P A|887|T S|885|T S|885|N 0 0 0 0 0.1860319284464423 Q02773 0.02384592592716217 0.17042240500450134 0.09669255465269087 0.10386353731155397 38.89416035041649 30.0 0.0 no 9897 chrXIII_88408r 26649 essential YML091C 2301 + ATCAGGAACTCACCCAGAGG I|768|M silent|ATC>ATT|I|768 0 0 0 0 -0.26464865698733964 Q02773 0.07200802117586136 51.31824351333131 55.00000000000001 0.0 no 9898 chrXIII_88411r 26650 essential YML091C 2298 + TTCATCAGGAACTCACCCAG F|767|L silent|TTC>TTT|F|767 I|768|M silent|ATC>ATT|I|768 0 0 0 0 0.8961851140367709 Q02773 1.0 0.07200802117586136 50.244683210878925 50.0 0.0 no 9899 chrXIII_88425r 26651 essential YML091C 2284 + TGTCACTAGGTTCTTTCATC S|763|* S|763|L L|764|V silent|CTA>TTA|L|764 0 0 0 0 -0.28442029308881794 Q02773 0.15361930429935455 0.0 48.01942989300886 40.0 0.0 no 9900 chrXIII_88549 26653 essential YML091C 2163 - ACGACACCTGCTAACAAATT V|728|L V|728|I V|727|L V|727|I 0 0 0 0 0.9448729615149074 Q02773 0.2889021635055542 0.3272756040096283 0.4242722690105438 0.5403344631195068 42.60026381986029 40.0 0.0 no 9901 chrXIII_88556 26654 essential YML091C 2156 - CTGCTAACAAATTAGGATCT A|725|P A|725|T 0 0 0 0 -0.37635710622979296 Q02773 0.3097532391548157 0.43439459800720215 39.52436409988286 35.0 0.0 no 9902 chrXIII_88706r 26655 essential YML091C 2003 + TCTGGAGATTCATGCAATTT L|669|V silent|CTG>TTG|L|669 0 0 0 0 0.08017397115403613 Q02773 0.1039479598402977 43.383739069096244 35.0 0.0 no 9903 chrXIII_89243 26659 essential YML091C 1469 - TCTTAGTCAAATTCCAATCT K|496|N silent|AAG>AAA|K|496 0 0 0 0 0.34919326772722464 Q02773 0.017607836052775383 41.23431604232928 30.0 0.0 no 9904 chrXIII_89285r 26660 essential YML091C 1424 + GTTCTCTTACGAATTTTATT F|476|L silent|TTC>TTT|F|476 S|477|C S|477|F 0 0 0 0 -0.31735314399748304 Q02773 0.0 0.025179974734783173 0.03893662244081497 39.085062823016926 25.0 0.0 no 9905 chrXIII_89340r 26661 essential YML091C 1369 + CTTCAAAAGCTTATGAAATA S|458|* S|458|L 0 0 0 0 -0.0954209142781493 Q02773 0.2839191854000092 32.947843453533324 25.0 0.0 no 9906 chrXIII_89369r 26662 essential YML091C 1340 + TTTCTTAATTTCGATGAGTA F|448|L silent|TTC>TTT|F|448 0 0 0 0 0.09933963220979987 Q02773 0.0 37.830001640947046 25.0 0.0 no 9907 chrXIII_89424 26663 essential YML091C 1288 - ACCATTTGAGCTTTGAATTT G|436|R G|436|S G|436|A G|436|D 0 0 0 0 0.6211704249494681 Q02773 0.0 0.0 0.0 0.0 42.83011898587489 30.0 0.0 no 9908 chrXIII_89425r 26664 essential YML091C 1284 + TCCAAAATTCAAAGCTCAAA silent|TCC>TCG|S|429 silent|TCC>TCT|S|429 S|429|C S|429|F 0 0 0 0 0.26351321759430835 Q02773 0.06697522103786469 0.13131879270076752 36.2521677094677 30.0 0.0 no 9909 chrXIII_89563r 26668 essential YML091C 1146 + TTCAGACTATCTTTATCATC F|383|L silent|TTC>TTT|F|383 L|385|V silent|CTA>TTA|L|385 0 0 0 0 0.027177119420437545 Q02773 0.031084312126040462 0.4004087746143341 40.471543483493406 30.0 0.0 no 9910 chrXIII_89586 26669 essential YML091C 1126 - ATCTTCATAAAGTTCTTTAA D|382|H D|382|N E|381|Q E|381|K 0 0 0 0 0.5635111265885734 Q02773 0.010262647643685341 0.024372782558202744 0.4929424822330475 0.14063136279582975 34.90873666073554 20.0 0.0 no 9911 chrXIII_89694 26671 essential YML091C 1018 - AACTTGTTGGGCTTTTGACA V|346|L V|346|I 0 0 0 0 0.10418928651458198 Q02773 0.6661821007728577 1.0 47.04603147964093 40.0 0.0 no 9912 chrXIII_89899r 26674 essential YML091C 810 + GTACTATTGTCTCTTTTCAA L|272|V silent|CTA>TTA|L|272 0 0 0 0 1.1050403485816394 Q02773 0.6631971597671509 42.692668379673755 30.0 0.0 no 9913 chrXIII_89951 26675 essential YML091C 761 - ATCTATTGTTGATCATATCT R|260|T R|260|K 0 0 0 0 0.2337195200712909 Q02773 0.01614333689212799 1.0 39.92708657970513 25.0 0.0 no 9914 chrXIII_90308 26681 essential YML091C 404 - TCCTATTACTAAAGTTTAAG R|141|T R|141|K R|141|S silent|AGG>AGA|R|141 0 0 0 0 0.6899110485606599 Q02773 0.6077540516853333 0.9293883442878724 0.7722553014755249 34.969934731089104 25.0 0.0 no 9915 chrXIII_90358r 26682 essential YML091C 351 + CAACATAGGTATTATTCTAC H|119|D H|119|Y 0 0 0 0 -1.0305748604273035 Q02773 0.23362500965595245 0.11245898902416228 37.150365527683725 30.0 0.0 no 9916 chrXIII_90566r 26688 essential YML091C 143 + ATCTCATCTACATCCTCATC S|49|C S|49|F H|50|D H|50|Y 0 0 0 0 -0.9657128512915804 Q02773 0.10078524053096773 0.14080803096294406 0.2415209859609604 1.0 48.548933628274824 40.0 0.0 no 9917 chrXIII_90602 26689 essential YML091C 110 - GATCCGAATTTACCAAACCT D|43|H D|43|N silent|TCG>TCC|S|42 silent|TCG>TCA|S|42 0 0 0 0 0.6402330940947242 Q02773 0.02667275816202164 0.06338970363140106 44.7794338637981 40.0 0.0 no 9918 chrXIII_98321r 26694 essential YML085C 941 + GGCTACTTGTCTGTTATACA A|315|G A|315|V T|316|S T|316|I TUB1 TUBulin 447.0 0 1 0 0 -0.7471173062675223 P09733 0.9030449986457824 0.8904849886894226 0.9216309785842896 0.9196789860725404 0.007187817711383104 0.002954439260065556 0.06662112474441527 0.0026279152370989323 0.7300599813461304 1.2750200033187866 0.6537399888038635 2.189879894256592 1.1150000095367432 1.3555999994277954 48.078239918814795 40.0 0.0 no 9919 chrXIII_98341 26696 essential YML085C 924 - GCCATGTATTTACCATCTCT M|314|I M|314|I A|315|P A|315|T TUB1 TUBulin 447.0 0 1 0 0 0.7136127791575718 P09733 0.9435129761695862 0.9435129761695862 0.8951879739761353 0.9085320234298706 0.04852226376533508 0.04852226376533508 0.003949202131479978 0.06996893137693405 1.3824399709701538 1.3824399709701538 3.3613600730896 -0.7520400285720825 1.9953999519348145 1.9953999519348145 3.908799886703491 0.4223999977111816 51.35158861062689 40.0 0.0 no 9920 chrXIII_98368 26697 essential YML085C 897 - CACTTGACCATCTGGTTACC K|305|N silent|AAG>AAA|K|305 TUB1 TUBulin 447.0 1 Series([], Name: modification, dtype: object) 0 0 0 -2.4725310359539856 P09733 0.9166929721832277 0.07042434811592102 0.4849599897861481 51.591315122231094 50.0 0.0 yes 9921 chrXIII_98504r 26700 essential YML085C 758 + GAACGAATTTCAAACCAATT N|254|K silent|AAC>AAT|N|254 TUB1 TUBulin 447.0 0 0 0 0 -0.35083926357133194 P09733 0.9845200181007384 0.09628929942846297 0.44161999225616455 35.85900810743027 30.0 0.0 no 9922 chrXIII_98545r 26701 essential YML085C 717 + ACAGCATCATTGAGATTCGA T|240|R T|240|I A|241|G A|241|V TUB1 TUBulin 447.0 0 0 0 0 0.11389543662581282 P09733 0.8242040276527405 0.863906979560852 0.9036229848861694 0.892562985420227 0.0012302794493734837 0.015415282920002937 0.008168740198016167 0.0908871963620186 4.279240131378174 2.5490400791168213 1.3503999710083008 0.3120200037956238 1.1030000448226929 -0.18639999628067014 44.716162159933155 40.0 0.0 no 9923 chrXIII_98579r 26702 essential YML085C 683 + AAACAACCTAATTGCTCAAG N|229|K silent|AAC>AAT|N|229 N|230|K silent|AAC>AAT|N|230 TUB1 TUBulin 447.0 0 0 0 0 -1.9144768302184176 P09733 0.7797510027885437 0.9845200181007384 0.002396249445155263 0.09399128705263138 0.9554399847984314 -0.5607200264930725 37.794031363641466 35.0 0.0 no 9924 chrXIII_98672r 26705 essential YML085C 590 + ACATGCAGATTGTACTTTCA H|198|D H|198|Y A|199|G A|199|V TUB1 TUBulin 447.0 0 0 0 0 0.8947591681271685 P09733 0.8512570261955261 0.8770110011100769 0.9919250011444092 0.991150975227356 0.08125819265842438 0.239298552274704 0.0548086054623127 0.18599240481853485 2.987339973449707 -0.2561799883842468 0.9953799843788148 0.0765800029039383 1.2893999814987185 -1.263200044631958 44.51574517955157 35.0 0.0 no 9925 chrXIII_98737 26706 essential YML085C 528 - ACCACAGAAGTAGACACTTG silent|GTG>GTC|V|182 silent|GTG>GTA|V|182 V|183|L V|183|I TUB1 TUBulin 447.0 0 0 0 0 0.6996597122519347 P09733 0.9278709888458252 0.9409509897232056 0.04048964008688927 0.00669271033257246 1.2770800590515137 -0.2614000141620636 -1.36080002784729 2.0074000358581543 43.92979789448947 45.0 0.0 no 9926 chrXIII_98738r 26707 essential YML085C 524 + TCCACAAGTGTCTACTTCTG P|176|R P|176|L P|176|A P|176|S TUB1 TUBulin 447.0 0 0 0 0 -0.8628333391360328 P09733 0.9148740172386168 0.90931898355484 0.934794008731842 0.9232450127601624 0.010591099038720131 0.0015850710915401578 0.051867686212062836 0.011219843290746212 0.9997199773788452 0.8783000111579895 0.8613600134849548 1.1969200372695925 48.49037990978962 45.0 0.0 no 9927 chrXIII_98780r 26709 essential YML085C 482 + ATACGGTAAGAAATCCAAGC Y|162|* silent|TAC>TAT|Y|162 TUB1 TUBulin 447.0 0 1 0 0 -1.1312347763935096 P09733 40.17593672076572 40.0 0.0 no 9928 chrXIII_98890r 26713 essential YML085C 372 + AAACTGGCAGACCAATGTGA L|126|V silent|CTG>TTG|L|126 TUB1 TUBulin 447.0 0 0 0 0 -0.6037972426335998 P09733 0.9090629816055298 0.1841655820608139 1.2448400259017944 0.8619999885559082 44.85424262028085 45.0 0.0 no 9929 chrXIII_98950r 26716 essential YML085C 312 + GCAAGAGGCCATTACACCGT A|105|G A|105|V TUB1 TUBulin 447.0 0 0 0 0 -1.4940785832217256 P09733 0.9088159799575806 0.8985810279846191 0.05860858783125876 0.031320657581090934 1.3472000360488892 4.957580089569092 0.026399999856948853 6.464600086212157 54.167226311623104 55.00000000000001 0.0 no 9930 chrXIII_98995 26720 essential YML085C 270 - TTACCACTGATCAACTGTTC G|96|A G|96|D G|96|R G|96|S TUB1 TUBulin 447.0 0 1 0 0 0.26803744945022345 P09733 0.8764259815216064 0.8478090167045593 0.8264690041542053 0.8942300081253052 0.07390707731246947 0.0040688696317374715 0.0035282548051327467 0.12381070852279664 2.141700029373169 2.549860000610352 4.136579990386963 2.9562599658966064 44.812075205055116 40.0 0.0 no 9931 chrXIII_99089r 26724 essential YML085C 173 + CTACGGTAAGTTCGTTCCAA Y|59|* silent|TAC>TAT|Y|59 TUB1 TUBulin 447.0 0 0 0 0 0.2409187438567333 P09733 47.36000066628105 45.0 0.0 no 9932 chrXIII_99090r 26725 essential YML085C 172 + GCTACGGTAAGTTCGTTCCA silent|GGC>GGG|G|58 silent|GGC>GGT|G|58 Y|59|* silent|TAC>TAT|Y|59 TUB1 TUBulin 447.0 0 0 0 0 -0.3614607308126834 P09733 52.61497716937174 50.0 0.0 no 9933 chrXIII_99136 26729 essential YML085C 129 - AAACCCTCTTCTCCTCCCTT G|49|A G|49|D G|49|R G|49|S TUB1 TUBulin 447.0 0 0 0 0 -2.9101279807381766 P09733 0.9903749823570251 0.9780880212783812 0.9727219939231871 0.9916149973869324 0.483613908290863 0.04277092218399048 0.026677297428250316 1.0 2.3759000301361084 8.085980415344237 2.289680004119873 3.087239980697632 58.797285895471475 50.0 0.0 yes 9934 chrXIII_99112r 26731 essential YML085C 150 + TCCACGTTTTTCCATGAAAC silent|TCC>TCG|S|51 silent|TCC>TCT|S|51 S|51|C S|51|F TUB1 TUBulin 447.0 0 0 0 0 -0.8082237112939391 P09733 0.9720100164413452 0.9521960020065308 0.02133053541183472 0.024918116629123688 -0.19711999595165253 -1.7010400295257568 45.304571065146554 40.0 0.0 no 9935 chrXIII_99188r 26734 essential YML085C 74 + CCTTGAGCACGGTATTAAGC L|26|V L|26|F TUB1 TUBulin 447.0 0 0 0 0 -0.9110965116780166 P09733 0.9591100215911864 0.9758340120315552 0.04897234216332436 0.01625376008450985 1.0649399757385254 -0.07735999673604965 1.348399996757507 0.6046000123023987 49.199158726375686 50.0 0.0 no 9936 chrXIII_99221r 26736 essential YML085C 41 + TCAGATTGGTAATGCCTGTT Q|15|E Q|15|* TUB1 TUBulin 447.0 0 0 0 0 -0.2303417498543444 P09733 0.9456779956817628 0.06388938426971437 -0.1829600036144257 48.06643661789098 40.0 0.0 no 9937 chrXIII_99235r 26738 essential YML085C 27 + GGTCAAGCTGGTTGTCAGAT Q|11|E Q|11|* TUB1 TUBulin 447.0 0 0 0 0 0.2260118125948891 P09733 0.9445829987525941 0.0 -0.22874000668525696 52.37316493268725 50.0 0.0 no 9938 chrXIII_111965r 26739 essential YML077W 103 - TGCATCTTCTTCATTCTGTT A|41|P A|41|T D|40|H D|40|N 0 0 0 0 0.08159311812236761 Q03630 0.9573720097541808 0.9523990154266356 0.9486550092697144 0.956179976463318 0.024059072136878967 0.1366567462682724 0.04200996458530426 0.26029306650161743 5.777679920196532 0.3136399984359741 2.8761000633239746 1.8901000022888184 48.858485436051524 35.0 1.0 no 9939 chrXIII_112025 26740 essential YML077W 160 + TTACACAAAAGCTCTCCAAA T|55|R T|55|I Q|56|E Q|56|* 0 0 0 0 0.27558693238767595 Q03630 0.9476869702339172 0.9472420215606691 0.9590039849281312 0.05027199536561966 0.42476165294647217 0.2519778907299042 12.062999725341795 -0.01080000028014183 39.79445575410682 35.0 1.0 no 9940 chrXIII_112096 26743 essential YML077W 231 + CACACATACTGTACAGCTTC H|78|Q silent|CAC>CAT|H|78 T|79|R T|79|I 0 0 0 0 0.6535577786827219 Q03630 0.9588389992713928 0.9476869702339172 0.9472420215606691 0.0 0.08730700612068176 0.11254067718982697 46.339689332452224 45.0 1.0 no 9941 chrXIII_112097 26744 essential YML077W 232 + ACACATACTGTACAGCTTCA T|79|R T|79|I H|78|Q silent|CAC>CAT|H|78 0 0 0 0 0.4581734416874826 Q03630 0.9476869702339172 0.9472420215606691 0.9588389992713928 0.08730700612068176 0.11254067718982697 0.0 46.339689332452224 40.0 1.0 no 9942 chrXIII_112103 26745 essential YML077W 238 + ACTGTACAGCTTCAGGGCTA Y|80|* silent|TAC>TAT|Y|80 T|82|R T|82|I 0 0 0 0 -1.106517316683288 Q03630 0.9476869702339172 0.9472420215606691 0.002801239257678389 0.003144795075058937 53.74945842114954 50.0 1.0 no 9943 chrXIII_112188r 26746 essential YML077W 326 - TCACGTATTTGACATAAATA V|115|L V|115|M silent|GTG>GTC|V|115 silent|GTG>GTA|V|115 0 0 0 0 -1.083489156704342 Q03630 0.9539830088615416 0.9587630033493042 0.0221484936773777 0.00429383572191 -0.9999799728393556 -1.69677996635437 35.09438163904798 25.0 1.0 no 9944 chrXIII_135532r 26747 essential YML069W 35 - ATCTACCGCTAAATTTAGAT R|18|T R|18|K G|17|A G|17|D POB3 POl1 Binding 552.0 0 1 0 0 0.2838664369913983 Q04636 0.8790010213851929 0.9003810286521912 0.7996929883956909 0.7462639808654785 0.040024463087320335 0.6190701723098755 0.0 0.0 0.4092360138893128 -0.4885599911212921 7.790703773498535 26.865100860595703 40.354793483238495 30.0 1.0 no 9945 chrXIII_135655 26750 essential YML069W 155 + ATCTACCGTCCAATGGAGTA S|53|C S|53|F T|54|S T|54|I POB3 POl1 Binding 552.0 0 0 0 0 0.3447214004573635 Q04636 0.905278980731964 0.893900990486145 0.905689001083374 0.8915460109710693 0.05651303753256798 0.061240740120410926 0.7723196148872375 0.21923471987247467 0.678413987159729 0.2304500043392181 0.11904200166463852 -0.4255880117416382 0.25707998871803284 -0.8271399736404419 49.65749496098903 45.0 1.0 no 9946 chrXIII_135778r 26757 essential YML069W 281 - CCTGAATATTAAAACGGCGA Q|100|H silent|CAG>CAA|Q|100 POB3 POl1 Binding 552.0 0 0 0 0 0.3633481091389087 Q04636 0.9392859935760498 0.11179612576961516 0.2370399981737137 40.16222230907306 40.0 1.0 no 9947 chrXIII_135850r 26760 essential YML069W 353 - AAACCATTTCATTCCTGGCA V|124|L V|124|I M|123|I M|123|I POB3 POl1 Binding 552.0 0 0 0 0 -0.0183792034777277 Q04636 0.9786369800567628 0.9863060116767884 0.9849619865417479 0.9849619865417479 0.582812488079071 0.5902553796768188 0.02915935032069683 0.02915935032069683 48.649735106401 40.0 1.0 no 9948 chrXIII_135855r 26761 essential YML069W 358 - AGCAAAAACCATTTCATTCC A|126|P A|126|T POB3 POl1 Binding 552.0 0 0 0 0 0.1035870830542427 Q04636 0.9863749742507936 0.9780830144882202 0.15740366280078888 0.33828142285346985 41.905959971956406 35.0 1.0 no 9949 chrXIII_135993r 26765 essential YML069W 496 - CATCTCTACCAATTCGTCAC E|171|D silent|GAG>GAA|E|171 E|171|Q E|171|K POB3 POl1 Binding 552.0 0 0 0 0 0.7353386622682141 Q04636 0.9933249950408936 1.0004899501800537 0.9891330003738404 0.10648287832736968 0.014838656410574913 0.011537525802850723 47.395017984322 45.0 1.0 no 9950 chrXIII_136256r 26769 essential YML069W 759 - TCGATATCATAACGACCTCT D|260|H D|260|N POB3 POl1 Binding 552.0 0 0 0 0 -0.061208579275338036 Q04636 0.7606949806213379 0.8279529809951782 0.0033700477797538038 0.01038137823343277 6.067490100860597 1.450600028038025 44.13914800250791 40.0 1.0 no 9951 chrXIII_136284 26770 essential YML069W 784 + ACAAGAACTCCATTAGACTC Y|262|* silent|TAC>TAT|Y|262 POB3 POl1 Binding 552.0 0 0 0 0 -0.4780464857332678 Q04636 41.881095869014636 40.0 1.0 no 9952 chrXIII_136293r 26771 essential YML069W 796 - GGTCTTACCCCTGAGTCTAA K|271|N silent|AAG>AAA|K|271 POB3 POl1 Binding 552.0 0 0 0 0 0.08415790290085898 Q04636 0.8447399735450745 0.0 0.24668000638484955 55.217138206014965 50.0 1.0 no 9953 chrXIII_136378 26772 essential YML069W 878 + TATCCATCACTTATTGGTTT I|294|M silent|ATC>ATT|I|294 H|295|D H|295|Y POB3 POl1 Binding 552.0 0 0 0 0 0.30885305603035185 Q04636 0.9195669889450072 0.8096420168876648 0.81768399477005 0.1720115691423416 0.030809147283434868 0.003970041405409575 0.543940007686615 3.493580102920532 -1.2698800563812256 44.77786015711894 30.0 1.0 no 9954 chrXIII_136381r 26773 essential YML069W 884 - TTGCCAAAACCAATAAGTGA A|301|P A|301|T L|300|F silent|TTG>TTA|L|300 POB3 POl1 Binding 552.0 0 0 0 0 -0.5985267062858061 Q04636 0.7822420001029968 0.800819993019104 0.7746170163154602 0.06819383800029755 0.10367909073829652 0.031641241163015366 0.300680011510849 0.9216200113296508 40.125480831572865 35.0 1.0 no 9955 chrXIII_136409r 26774 essential YML069W 912 - GTCTGTCCTTGACGTAAAGG Q|310|H silent|CAG>CAA|Q|310 G|309|A G|309|E POB3 POl1 Binding 552.0 0 0 0 0 -0.4483134275833413 Q04636 0.9398229718208312 0.9610270261764526 0.9553980231285096 0.0 0.0 0.0 0.20137999951839447 3.5393600463867188 2.6402599811553955 48.24752205313479 50.0 1.0 no 9956 chrXIII_136629r 26776 essential YML069W 1132 - AACTGCACACTGATCATATT V|384|L V|384|I A|383|P A|383|T POB3 POl1 Binding 552.0 0 0 0 0 0.11465465159442098 Q04636 0.8310070037841797 0.8527370095252991 0.7952529788017273 0.8076450228691101 0.2641705870628357 0.4621168375015259 0.05858565866947174 0.040768735110759735 -1.8285399675369265 -0.872439980506897 1.773360013961792 2.4380600452423096 42.18861188908181 35.0 1.0 no 9957 chrXIII_136735 26777 essential YML069W 1235 + ACCATTCAGTGATGTTAGCA P|413|R P|413|L P|413|A P|413|S POB3 POl1 Binding 552.0 0 0 0 0 -0.10534487989077894 Q04636 0.7735990285873413 0.7612069845199585 0.8111289739608765 0.8237000107765198 0.0962166264653206 0.060473803430795676 0.3198031783103943 0.310105174779892 2.253119945526123 1.5801399946212769 1.8548799753189087 2.3007400035858154 48.614763523537086 40.0 1.0 no 9958 chrXIII_136736r 26778 essential YML069W 1239 - ACCATGCTAACATCACTGAA M|419|I M|419|I V|420|L V|420|I POB3 POl1 Binding 552.0 0 0 0 0 -1.1190652861038777 Q04636 0.9353280067443848 0.9353280067443848 0.9132850170135498 0.9300820231437684 0.4141941666603088 0.4141941666603088 0.04178354516625405 0.6641594171524048 3.242079973220825 3.242079973220825 -0.05542000010609627 -0.8327800035476685 44.236946472002494 40.0 1.0 no 9959 chrXIII_142302r 26780 essential YML065W 95 - GTTCAGTTTTTGCACCTCTT E|38|Q E|38|K ORC1 Origin Recognition Complex 914.0 0 0 0 0 0.30378631465842043 P54784 0.9564459919929504 0.932539999485016 0.5489922165870667 0.7009823322296143 0.3396799862384796 0.4028399884700775 52.783819567793614 40.0 1.0 no 9960 chrXIII_142404 26782 essential YML065W 194 + TTACTCCGTTTATATGATCC Y|66|* silent|TAC>TAT|Y|66 S|67|C S|67|F ORC1 Origin Recognition Complex 914.0 0 0 0 0 -0.29275514197855634 P54784 0.5303509831428528 0.5177800059318542 0.008315889164805412 0.00554206408560276 -0.5203400254249573 -2.0976400375366206 45.215243727922314 35.0 1.0 no 9961 chrXIII_142496 26784 essential YML065W 286 + TCAATCCTTTAGCTCATTAT silent|GTC>GTG|V|96 silent|GTC>GTT|V|96 P|98|A P|98|S ORC1 Origin Recognition Complex 914.0 0 0 0 0 -0.4632549923286964 P54784 0.8606029748916626 0.7947080135345459 0.4654062688350678 0.09445443004369736 1.8835999965667725 2.776240110397339 44.12745738147396 30.0 1.0 no 9962 chrXIII_142475r 26785 essential YML065W 268 - GACTTCAAACCATCGTAAAT V|96|L V|96|I E|95|Q E|95|K ORC1 Origin Recognition Complex 914.0 0 0 0 0 1.146910210263174 P54784 0.8797199726104736 0.8674110174179077 0.8117009997367859 0.778626024723053 0.8100578784942627 1.0 0.030015476047992706 0.02370881475508213 2.762200117111206 -0.12217999994754793 0.09743999689817427 0.19718000292778012 0.003599999938160181 -0.007720000110566616 39.50250092182142 35.0 1.0 no 9963 chrXIII_142501r 26786 essential YML065W 294 - AACTGCCTATAATGAGCTAA Q|104|H silent|CAG>CAA|Q|104 R|103|S silent|AGG>AGA|R|103 ORC1 Origin Recognition Complex 914.0 0 0 0 0 -0.07724500420351249 P54784 0.9568089842796326 0.9360870122909546 0.5903691053390503 0.7046111822128296 -0.23615999519824984 0.3513199985027313 41.49767241899127 35.0 1.0 no 9964 chrXIII_142632 26788 essential YML065W 422 + GCAGCTATTTAACTTTATCA Q|142|E Q|142|* L|143|V silent|CTA>TTA|L|143 ORC1 Origin Recognition Complex 914.0 0 0 0 0 -1.609895081505485 P54784 0.8394219875335693 0.8235909938812256 0.6326711177825928 0.0 0.5341200232505798 2.001440048217773 2.0659399032592773 42.07320077549985 30.0 1.0 no 9965 chrXIII_142744r 26793 essential YML065W 537 - TCCACAAATTTCTCCCCAGT silent|GTG>GTC|V|185 silent|GTG>GTA|V|185 D|186|H D|186|N ORC1 Origin Recognition Complex 914.0 0 0 0 0 1.076086065284639 P54784 0.9335169792175292 0.9866480231285096 0.0854593887925148 0.29826945066452026 -0.02342000044882297 0.25181999802589417 53.412278831906 45.0 1.0 no 9966 chrXIII_142929 26796 essential YML065W 719 + AACAAGAGCTACAGATATAA T|241|R T|241|I ORC1 Origin Recognition Complex 914.0 0 1 0 0 -0.07638883334065982 P54784 0.9605219960212708 0.9707369804382324 0.5403915643692017 0.23139123618602755 35.04463857160221 30.0 1.0 no 9967 chrXIII_143042r 26798 essential YML065W 835 - TTCTTCCTCAAGCTCATCTG E|285|Q E|285|K E|284|Q E|284|K ORC1 Origin Recognition Complex 914.0 0 0 0 0 0.5380498831449888 P54784 0.9437350034713744 0.93743497133255 0.9798020124435424 0.978296995162964 0.2812618017196655 0.8128886222839355 0.5175725817680359 0.7962785959243774 50.97899930047805 45.0 1.0 no 9968 chrXIII_143122r 26799 essential YML065W 915 - ATCTTACGGCCTCTTTTCCT K|311|N silent|AAG>AAA|K|311 R|310|P R|310|H ORC1 Origin Recognition Complex 914.0 0 0 0 0 0.4188402827732237 P54784 1.0127600431442259 0.9055359959602356 0.8912349939346313 0.5153223872184753 0.039578936994075775 0.03153833374381065 55.47518187721557 45.0 1.0 no 9969 chrXIII_143179 26800 essential YML065W 969 + CAACCTCCCCCCAAAAAAAG P|325|A P|325|S P|325|R P|325|L ORC1 Origin Recognition Complex 914.0 0 0 0 0 -0.3953791551234804 P54784 1.0358099937438965 1.0326700210571291 1.0194499492645264 1.0118600130081177 0.5920255184173584 0.6696755290031433 0.5476167201995851 0.25329387187957764 46.947316330639524 50.0 1.0 no 9970 chrXIII_143209r 26801 essential YML065W 1002 - CGCGGTTTACTAGGATCTTT silent|CCG>CCC|P|340 silent|CCG>CCA|P|340 ORC1 Origin Recognition Complex 914.0 0 0 0 0 0.04214222790271563 P54784 48.88757247867028 45.0 1.0 no 9971 chrXIII_143256r 26803 essential YML065W 1049 - TCACAGGAGTATTATTTGCA V|356|L V|356|M silent|GTG>GTC|V|356 silent|GTG>GTA|V|356 ORC1 Origin Recognition Complex 914.0 0 0 0 0 1.3781652357737508 P54784 1.0040199756622314 1.0035799741744995 0.3131626844406128 0.11419989913702012 44.142657335119054 35.0 1.0 no 9972 chrXIII_143288 26804 essential YML065W 1078 + TTACAAAAAAGAATGTTGCT T|361|R T|361|I ORC1 Origin Recognition Complex 914.0 0 0 0 0 0.465203002700139 P54784 0.8870180249214172 0.9170389771461488 0.1286190003156662 0.09854258596897124 32.481291873718305 25.0 1.0 no 9973 chrXIII_143289 26805 essential YML065W 1079 + TACAAAAAAGAATGTTGCTA T|361|R T|361|I ORC1 Origin Recognition Complex 914.0 0 0 0 0 0.520618123233391 P54784 0.8870180249214172 0.9170389771461488 0.1286190003156662 0.09854258596897124 31.783386687190447 25.0 1.0 no 9974 chrXIII_143374 26806 essential YML065W 1164 + ACTTCATTACCTGAATTTTA T|389|S T|389|I S|390|* S|390|L ORC1 Origin Recognition Complex 914.0 0 0 0 0 0.4991200948242761 P54784 1.0187699794769287 0.9702270030975342 0.9584580063819884 0.6396058797836304 0.17550602555274966 0.06501280516386032 39.82128872297528 25.0 1.0 no 9975 chrXIII_143447r 26807 essential YML065W 1240 - TTCTACAATCTGATGCTTTT E|420|Q E|420|K V|419|L V|419|I ORC1 Origin Recognition Complex 914.0 0 0 0 0 0.5820496992763942 P54784 0.8863000273704529 0.8798760175704956 0.9725840091705322 0.9800879955291748 0.10714470595121384 0.11512462049722673 0.1700560450553894 0.2243139147758484 42.15871217468651 30.0 1.0 no 9976 chrXIII_143543 26808 essential YML065W 1333 + TCCAAGATTATTTACCGGCT Q|446|E Q|446|* F|445|L silent|TTC>TTT|F|445 ORC1 Origin Recognition Complex 914.0 0 0 0 0 -0.11926181443807295 P54784 0.94609397649765 0.9389600157737732 1.0 0.9613659977912904 47.9771166579618 40.0 1.0 no 9977 chrXIII_143448r 26809 essential YML065W 1241 - TTTCTACAATCTGATGCTTT E|420|Q E|420|K V|419|L V|419|I ORC1 Origin Recognition Complex 914.0 0 0 0 0 0.22257354593218576 P54784 0.8863000273704529 0.8798760175704956 0.9725840091705322 0.9800879955291748 0.10714470595121384 0.11512462049722673 0.1700560450553894 0.2243139147758484 42.158712174686464 30.0 1.0 no 9978 chrXIII_143402 26810 essential YML065W 1192 + CTTCGGAATTGATGGCATCA S|399|W S|399|L ORC1 Origin Recognition Complex 914.0 0 0 0 0 -0.024684407138637177 P54784 0.7779139876365662 0.9508050084114076 0.03245487064123154 0.3612857758998871 46.627813483578855 45.0 1.0 no 9979 chrXIII_143544 26811 essential YML065W 1334 + CCAAGATTATTTACCGGCTA Q|446|E Q|446|* ORC1 Origin Recognition Complex 914.0 0 0 0 0 0.5315267517631278 P54784 0.94609397649765 1.0 46.48948232134558 40.0 1.0 no 9980 chrXIII_143544r 26812 essential YML065W 1337 - CCCTAGCCGGTAAATAATCT R|452|T R|452|K R|452|S silent|AGG>AGA|R|452 ORC1 Origin Recognition Complex 914.0 0 0 0 0 0.007880005619985319 P54784 0.7793759703636169 0.8301380276679993 0.7563009858131409 0.011869171634316444 0.18726696074008944 0.00946205947548151 48.58028881209435 45.0 1.0 no 9981 chrXIII_143557r 26813 essential YML065W 1350 - GCGAATTCATTCTCCCTAGC A|457|P A|457|T ORC1 Origin Recognition Complex 914.0 0 0 0 0 0.6844966208335359 P54784 0.8511779904365541 0.926483988761902 0.047298144549131386 0.2395758330821991 52.94243564015994 50.0 1.0 no 9982 chrXIII_143623 26814 essential YML065W 1413 + GCTACTACTATATACGTGGC A|472|G A|472|V T|473|S T|473|I ORC1 Origin Recognition Complex 914.0 0 0 0 0 -0.9680759175789452 P54784 0.9502559900283812 0.8383679986000061 0.9365230202674866 0.8493040204048157 0.5718728303909302 0.03669402003288269 0.4181178212165833 0.03657129034399986 46.72774811883824 45.0 1.0 no 9983 chrXIII_143888r 26820 essential YML065W 1681 - TTCGTCCAACAAGACTACAA E|567|Q E|567|K D|566|H D|566|N ORC1 Origin Recognition Complex 914.0 0 0 0 0 -4.6136520094277484 P54784 0.8464440107345581 0.8450689911842346 0.7617930173873901 0.7909619808197021 0.0 0.0 0.0 0.0 42.47402611168417 40.0 1.0 yes 9984 chrXIII_143918r 26821 essential YML065W 1711 - ATCTTGAGATTTCGTTACCA D|577|H D|577|N ORC1 Origin Recognition Complex 914.0 0 0 0 0 0.276044086328294 P54784 0.8445619940757751 0.935338020324707 0.01252488046884537 0.2141610085964203 45.336110930005646 35.0 1.0 no 9985 chrXIII_144005r 26822 essential YML065W 1798 - TTCTGGTAAGTCCATTGTAT E|606|Q E|606|K ORC1 Origin Recognition Complex 914.0 0 0 0 0 -1.4509027049437977 P54784 0.8571299910545349 0.8524429798126221 0.0 0.0 46.16934318182592 35.0 1.0 no 9986 chrXIII_144016 26823 essential YML065W 1806 + GACTTACCAGAACGTCAGCT D|603|E silent|GAC>GAT|D|603 P|605|A P|605|S ORC1 Origin Recognition Complex 914.0 0 0 0 0 0.014392532134514968 P54784 0.8579109907150269 0.8507850170135498 0.7857149839401245 0.0 0.0 0.0 49.69541384655885 50.0 1.0 no 9987 chrXIII_144065 26824 essential YML065W 1855 + TTACCAGAATTATGTTCACT T|620|S T|620|I silent|ACC>ACG|T|620 silent|ACC>ACT|T|620 ORC1 Origin Recognition Complex 914.0 0 0 0 0 1.0154782783665812 P54784 0.8974320292472839 0.8715999722480774 0.17275334894657135 0.028606621548533436 41.31871558517605 30.0 1.0 no 9988 chrXIII_144068r 26825 essential YML065W 1861 - ATACCCAGTGAACATAATTC silent|GGG>GGC|G|626 silent|GGG>GGA|G|626 G|626|A G|626|E ORC1 Origin Recognition Complex 914.0 0 0 0 0 -0.09413701096583643 P54784 0.9170979857444764 0.8480039834976196 0.0 0.0 41.449759318344654 35.0 1.0 no 9989 chrXIII_144111 26826 essential YML065W 1901 + TATCATTGATTTAAGACTGA I|635|M silent|ATC>ATT|I|635 ORC1 Origin Recognition Complex 914.0 0 0 0 0 0.03108444771338855 P54784 0.8234540224075317 0.0 35.61289145202949 25.0 1.0 no 9990 chrXIII_144112 26827 essential YML065W 1902 + ATCATTGATTTAAGACTGAA I|635|M silent|ATC>ATT|I|635 ORC1 Origin Recognition Complex 914.0 0 0 0 0 0.1411590463664219 P54784 0.8234540224075317 0.0 34.893223235813025 25.0 1.0 no 9991 chrXIII_145441r 26833 essential YML064C 413 + AGACTTAGACCCGGAATATC D|139|E silent|GAC>GAT|D|139 TEM1 TErmination of M phase 245.0 0 0 0 0 -1.0343525836984129 P38987 0.8852724432945251 45.563403129582404 45.0 0.0 no 9992 chrXIII_145485r 26834 essential YML064C 369 + TCGGCAATTCCTATTTTGGT S|124|W S|124|L A|125|G A|125|V TEM1 TErmination of M phase 245.0 0 0 0 0 -0.004749061635476004 P38987 0.002965926192700863 0.011488988995552065 0.2630634903907776 0.857395350933075 0.4909999966621399 0.3239800035953522 49.258870671573106 40.0 0.0 no 9993 chrXIII_145601r 26838 essential YML064C 253 + TGCTCCCAATTGCGACGGTA L|86|V L|86|F silent|CTC>CTG|L|86 silent|CTC>CTT|L|86 TEM1 TErmination of M phase 245.0 0 0 0 0 -0.4334819993677674 P38987 0.1879594922065735 0.11510350555181505 1.4909199476242063 5.081480026245117 54.60704878703053 55.00000000000001 0.0 no 9994 chrXIII_145606r 26839 essential YML064C 248 + CAACATGCTCCCAATTGCGA N|84|K silent|AAC>AAT|N|84 TEM1 TErmination of M phase 245.0 0 0 0 0 -0.21019533249169128 P38987 0.036685500293970115 -0.6244000196456909 50.371568810639296 50.0 0.0 no 9995 chrXIII_145818 26842 essential YML064C 39 - TCAACCTGATTTCGTACCGC E|20|Q E|20|K V|19|L V|19|I TEM1 TErmination of M phase 245.0 0 0 0 0 0.3604078105759441 P38987 0.4633930623531342 0.7019410133361816 0.2676067650318146 0.5469599962234497 50.73165438864913 50.0 0.0 no 9996 chrXIII_145834r 26843 essential YML064C 20 + AGCAAACAATTCTATACCTG A|8|G A|8|V N|9|K silent|AAC>AAT|N|9 TEM1 TErmination of M phase 245.0 0 0 0 0 0.4095522718960426 P38987 0.4636116325855255 0.3152309060096741 0.9068883657455444 39.8088988004036 35.0 0.0 no 9997 chrXIII_175431 26846 essential YML049C 2855 - CATCAATTTGCAGTGATATA D|958|H D|958|N RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 0.7355244064170227 Q04693 0.11241689324378967 1.0 39.43356321238213 30.0 0.0 no 9998 chrXIII_175478 26847 essential YML049C 2808 - TCAATAAACAAAATGCTTTT D|943|H D|943|N RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 0.34675519195140336 Q04693 0.07114321738481523 0.4272136092185974 31.528229044197193 20.0 0.0 no 9999 chrXIII_175651r 26848 essential YML049C 2632 + ACTTTCCAACTTTGGATAAC N|878|K silent|AAC>AAT|N|878 P|880|A P|880|S RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 0.3930742216304736 Q04693 0.6366285681724548 0.985421359539032 0.9956119656562804 41.496649657000496 35.0 0.0 no 10000 chrXIII_175735 26851 essential YML049C 2551 - AACATCTGCGTTAACAAATT V|857|L V|857|I D|856|H D|856|N RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 -0.673024384706008 Q04693 0.30653300881385803 1.0 0.043907582759857185 0.6903402209281921 37.54260279122076 30.0 0.0 no 10001 chrXIII_175824r 26853 essential YML049C 2459 + TTGCCATTCCTCTTCTACAT C|821|W silent|TGC>TGT|C|821 H|822|D H|822|Y RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 -0.6698532581852712 Q04693 0.007555696181952953 0.04625338688492775 0.11558400094509125 52.48950701632685 40.0 0.0 no 10002 chrXIII_175957 26855 essential YML049C 2329 - TATCTCACGCAAATACGAAA E|782|D silent|GAG>GAA|E|782 E|782|Q E|782|K RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 -0.3170001050902711 Q04693 0.66740882396698 0.4988731145858765 0.7751395702362059 37.69295382453964 35.0 0.0 no 10003 chrXIII_176005r 26858 essential YML049C 2278 + GATCGTTCACTGACATAAAA S|761|W S|761|L RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 0.09338545266828764 Q04693 0.021455902606248856 0.3545086681842804 38.28062345739039 35.0 0.0 no 10004 chrXIII_176075r 26861 essential YML049C 2208 + GGACAGCTTAATTTGCATGT Q|738|E Q|738|* L|739|V L|739|F RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 -0.2080117534214609 Q04693 1.0 0.29761993885040283 0.04950295388698578 46.32754080185112 40.0 0.0 no 10005 chrXIII_176257 26862 essential YML049C 2029 - TTGCACAATCGCAACTTTAG silent|GTG>GTC|V|682 silent|GTG>GTA|V|682 V|682|L V|682|M RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 0.208100952407213 Q04693 0.4992172718048096 0.1728377789258957 42.74413076082476 40.0 0.0 no 10006 chrXIII_176258 26863 essential YML049C 2028 - TGCACAATCGCAACTTTAGA silent|GTG>GTC|V|682 silent|GTG>GTA|V|682 V|682|L V|682|M RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 1.4182653470437163 Q04693 0.4992172718048096 0.1728377789258957 43.64044938072027 40.0 0.0 no 10007 chrXIII_176408 26864 essential YML049C 1878 - ACAATACGAATTCCCGCTGG V|633|L V|633|I R|631|P R|631|H RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 0.2433772915017995 Q04693 0.23005710542202 0.3603205382823944 0.10168865323066713 0.2723996937274933 47.82236902810274 50.0 0.0 no 10008 chrXIII_176473 26867 essential YML049C 1813 - TACGATATGTCTTAGTTCTG V|611|L V|611|I RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 -1.0623373287941889 Q04693 0.3315301239490509 0.44248321652412415 41.52795079168675 35.0 0.0 no 10009 chrXIII_176522r 26868 essential YML049C 1761 + ACAATTCATACATGCCTAAT T|588|R T|588|I H|590|D H|590|Y RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 0.03715821870885473 Q04693 0.0058305016718804845 0.006397764664143324 0.2016506791114807 1.0 40.67113631866045 30.0 0.0 no 10010 chrXIII_176701 26874 essential YML049C 1585 - CCATAACTTGGTTGCGTTCG W|535|S W|535|* K|533|N silent|AAG>AAA|K|533 RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 0.363200033174096 Q04693 0.0 1.0 49.57112145686909 50.0 0.0 no 10011 chrXIII_176906 26876 essential YML049C 1380 - TCGAAAACTAGCGACTTATT E|467|Q E|467|K RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 -0.01293039010406255 Q04693 0.2782791256904602 0.8427507281303406 38.816261017000045 35.0 0.0 no 10012 chrXIII_176967 26877 essential YML049C 1319 - CTACACCAAGTTTCTCAAAC V|446|L V|446|I G|445|A G|445|D RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 -0.11430024153929745 Q04693 0.2500303387641907 0.15460482239723206 0.031215060502290726 0.16906431317329407 42.02526042227987 40.0 0.0 no 10013 chrXIII_177149r 26878 essential YML049C 1134 + GTACTTTTACAATCTAACCA L|380|V L|380|F RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 0.02076626288354552 Q04693 0.03387710079550743 0.02363176271319389 40.3461237884855 30.0 0.0 no 10014 chrXIII_177232 26879 essential YML049C 1054 - GCTATTTGTGATAGATCTTT S|358|T S|358|N RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 -0.3292003697909948 Q04693 0.4831787645816803 0.7358989119529724 42.259083189152314 30.0 0.0 no 10015 chrXIII_177297r 26881 essential YML049C 986 + AGGCTTCGAAAATCATATTC silent|GGC>GGG|G|330 silent|GGC>GGT|G|330 F|331|L silent|TTC>TTT|F|331 RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 -0.3689450590664163 Q04693 0.295125275850296 39.4766537562702 35.0 0.0 no 10016 chrXIII_177317r 26882 essential YML049C 966 + TTCAACCCTTTTGTTGTCAT F|323|L silent|TTC>TTT|F|323 N|324|K silent|AAC>AAT|N|324 RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 0.5749788306969197 Q04693 0.1167825683951378 0.0 48.65391428223319 35.0 0.0 no 10017 chrXIII_177409 26885 essential YML049C 877 - TGGCAAACTCAGTACGAAAT L|298|F silent|TTG>TTA|L|298 RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 0.3936582245224021 Q04693 0.03055825643241405 40.387000344503285 40.0 0.0 no 10018 chrXIII_177585 26888 essential YML049C 701 - CCATATCCAGCGTTACCATA M|240|I M|240|I D|239|H D|239|N RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 -0.1084038164564956 Q04693 0.5140286087989807 0.5140286087989807 0.11906829476356505 0.4908596873283386 51.79124473374179 45.0 0.0 no 10019 chrXIII_177585r 26889 essential YML049C 698 + CCATATGGTAACGCTGGATA H|234|D H|234|Y RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 0.3172232043125709 Q04693 0.6744746565818787 0.03255988657474518 46.71442974714132 45.0 0.0 no 10020 chrXIII_177709r 26890 essential YML049C 574 + ACATGGAAATTGACCCTAAT Y|192|* silent|TAC>TAT|Y|192 RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 -0.9001872257488502 Q04693 41.25404310808102 35.0 0.0 no 10021 chrXIII_177718 26891 essential YML049C 568 - GTCAATTTCCATGTATGATA D|196|H D|196|N RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 0.20697953512096035 Q04693 0.00619653332978487 0.01911988668143749 41.72872168376432 30.0 0.0 no 10022 chrXIII_177719 26892 essential YML049C 567 - TCAATTTCCATGTATGATAT D|196|H D|196|N RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 -1.2286822243947904 Q04693 0.00619653332978487 0.01911988668143749 39.27364188171856 25.0 0.0 no 10023 chrXIII_177726r 26893 essential YML049C 557 + AGTCTCTCCCATATCATACA silent|GTC>GTG|V|187 silent|GTC>GTT|V|187 S|188|C S|188|F RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 0.5886255564814299 Q04693 0.008295118808746338 0.0036505563184618954 50.650474411718214 40.0 0.0 no 10024 chrXIII_177980r 26900 essential YML049C 303 + GAACTTTATGATACTGCAGA L|103|V L|103|F RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 0.8507456643392901 Q04693 0.033709142357110984 0.02356709912419319 40.312062228468506 35.0 0.0 no 10025 chrXIII_177979r 26901 essential YML049C 304 + AACTTTATGATACTGCAGAT L|103|V L|103|F RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 0.6436642314761625 Q04693 0.033709142357110984 0.02356709912419319 39.11554091247189 30.0 0.0 no 10026 chrXIII_178146 26906 essential YML049C 140 - TAGCAACCATTGTTATGTTA A|53|P A|53|T V|52|L V|52|I RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 0.2394232046900476 Q04693 0.2837368845939636 0.5892048478126526 1.0 0.8529213666915894 42.46960185217756 30.0 0.0 no 10027 chrXIII_178205r 26907 essential YML049C 78 + AGCACAACGATGGCTTATGA S|27|R silent|AGC>AGT|S|27 T|28|R T|28|I RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 0 0 0 -1.9334387886793527 Q04693 46.063638811220464 45.0 0.0 no 10028 chrXIII_178244 26909 essential YML049C 42 - TTACGCATCTTCGCCGTGTG R|20|P R|20|H M|19|I M|19|I RSE1 RNA Splicing and ER-to-Golgi transport 1361.0 0 1 0 0 0.32100638277307664 Q04693 54.092774758078185 55.00000000000001 0.0 no 10029 chrXIII_181513 26910 essential YML046W 39 + CCTAGGCCTGATGCCCTTCG P|14|R P|14|L P|16|A P|16|S PRP39 Pre-mRNA Processing 629.0 0 0 0 0 -0.5897318725883398 P39682 61.844336777301976 65.0 1.0 no 10030 chrXIII_181619r 26916 essential YML046W 148 - CTCTATAACATCTACCATTT E|56|Q E|56|K PRP39 Pre-mRNA Processing 629.0 0 0 0 0 0.38403631587386505 P39682 0.0 0.0 41.361686548699254 30.0 1.0 no 10031 chrXIII_181666r 26918 essential YML046W 195 - GCCAATTTGATTGAATCATT L|71|F silent|TTG>TTA|L|71 A|72|P A|72|T PRP39 Pre-mRNA Processing 629.0 0 0 0 0 -0.10230374055317032 P39682 0.3935539424419403 0.2836763262748718 0.699830174446106 40.90303103982029 30.0 1.0 no 10032 chrXIII_181685 26919 essential YML046W 211 + TGGCCTTGGAAACTATTTTA A|72|G A|72|V silent|GCC>GCG|A|72 silent|GCC>GCT|A|72 PRP39 Pre-mRNA Processing 629.0 0 0 0 0 0.3742669047845916 P39682 0.5520870685577393 0.25018852949142456 43.727395073094605 35.0 1.0 no 10033 chrXIII_181688r 26920 essential YML046W 217 - TTGCCATAAAATAGTTTCCA W|78|C W|78|* W|78|S W|78|* PRP39 Pre-mRNA Processing 629.0 0 0 0 0 -0.4037321826633847 P39682 0.054217923432588584 0.6733297109603882 42.012271613553885 30.0 1.0 no 10034 chrXIII_181759 26921 essential YML046W 285 + ACTATTGAGTACCAGTTATT T|96|S T|96|I PRP39 Pre-mRNA Processing 629.0 0 0 0 0 1.220761751298727 P39682 0.07853968441486359 0.007520710583776236 42.48422248711381 30.0 1.0 no 10035 chrXIII_181802 26922 essential YML046W 328 + TTCTGGCCACCTCGGTCAAA L|111|V silent|CTG>TTG|L|111 A|112|G A|112|V PRP39 Pre-mRNA Processing 629.0 0 0 0 0 0.7894552711245084 P39682 0.0 0.3735998868942261 0.28163355588912964 55.43994507610489 55.00000000000001 1.0 no 10036 chrXIII_182188 26925 essential YML046W 714 + AAACAGCCCTTCTTCAACCT Q|240|E Q|240|* P|241|A P|241|S PRP39 Pre-mRNA Processing 629.0 0 0 0 0 -0.5242403078734125 P39682 0.055320437997579575 0.8066492080688477 1.0 50.92810239521492 45.0 1.0 no 10037 chrXIII_182205r 26926 essential YML046W 734 - CATCATTTAACACTTGGCCC D|251|H D|251|N PRP39 Pre-mRNA Processing 629.0 0 0 0 0 -0.2905877949116218 P39682 0.12122094631195067 0.5096060633659363 49.105042873755856 45.0 1.0 no 10038 chrXIII_182211 26927 essential YML046W 737 + CCAAGTGTTAAATGATGATT Q|247|E Q|247|* PRP39 Pre-mRNA Processing 629.0 0 0 0 0 1.1060839777918612 P39682 1.0 37.67319485950958 30.0 1.0 no 10039 chrXIII_182211r 26928 essential YML046W 740 - CCAAATCATCATTTAACACT L|253|F silent|TTG>TTA|L|253 D|252|H D|252|N PRP39 Pre-mRNA Processing 629.0 0 0 0 0 0.05849762203042585 P39682 0.06860107183456421 0.005807743407785893 0.012579094618558884 38.834207514422594 30.0 1.0 no 10040 chrXIII_182262 26929 essential YML046W 788 + GACGGATCCTTCAAAATCCT T|264|R T|264|M PRP39 Pre-mRNA Processing 629.0 0 0 0 0 -0.5287349967495371 P39682 0.043206680566072464 0.07409857958555223 46.78272393187393 45.0 1.0 no 10041 chrXIII_182330 26930 essential YML046W 856 + GTCTTTACCATGAAAATACG L|287|V L|287|F PRP39 Pre-mRNA Processing 629.0 0 0 0 0 0.07252139536564782 P39682 0.5022810697555542 0.6992639899253845 38.461103715182965 35.0 1.0 no 10042 chrXIII_182337r 26931 essential YML046W 866 - ACATCATCCACGTATTTTCA M|295|I M|295|I M|294|I M|294|I PRP39 Pre-mRNA Processing 629.0 0 0 0 0 -0.5871853206358872 P39682 0.12876367568969727 0.12876367568969727 0.3308432996273041 0.3308432996273041 46.13363401839371 35.0 1.0 no 10043 chrXIII_182437r 26932 essential YML046W 966 - CTCAAAGTTTTGAAATCCAG L|328|F silent|TTG>TTA|L|328 PRP39 Pre-mRNA Processing 629.0 0 0 0 0 0.8263920788484793 P39682 0.32584500312805176 38.356335326666176 35.0 1.0 no 10044 chrXIII_182537 26933 essential YML046W 1063 + TATCGCGTTATTTAAAGATT S|356|W S|356|L R|357|G R|357|C PRP39 Pre-mRNA Processing 629.0 0 0 0 0 0.4066465001446777 P39682 0.18438540399074554 0.668158233165741 0.3640235364437103 0.18049989640712735 36.95057693314703 25.0 1.0 no 10045 chrXIII_182560r 26935 essential YML046W 1089 - GTCATAAGTAATATGTCGTT M|369|I M|369|I PRP39 Pre-mRNA Processing 629.0 0 0 0 0 -0.664451731996139 P39682 0.6962215900421143 0.6962215900421143 39.283856502298704 30.0 1.0 no 10046 chrXIII_182562 26936 essential YML046W 1088 + CAACGACATATTACTTATGA N|364|K silent|AAC>AAT|N|364 D|365|E silent|GAC>GAT|D|365 PRP39 Pre-mRNA Processing 629.0 0 0 0 0 0.2422236840711827 P39682 0.4804879724979401 0.5070165395736694 36.58025001217357 30.0 1.0 no 10047 chrXIII_190677 26937 essential YML043C 1071 - ACTTCAGCGTCTTCCATAAA V|364|L V|364|I E|363|Q E|363|K 0 0 0 0 -0.6483103561164439 Q04712 0.07386388629674911 0.6644068956375122 0.0 0.0 47.070755163191855 40.0 0.0 no 10048 chrXIII_190680 26938 essential YML043C 1068 - TCAGCGTCTTCCATAAACGG E|363|Q E|363|K A|362|P A|362|T 0 0 0 0 -1.3496552233844494 Q04712 0.0 0.0 1.0 0.09123583137989044 48.40721020352396 50.0 0.0 no 10049 chrXIII_190860 26942 essential YML043C 888 - GTTCTAGAACCGGTTTGAAA R|302|T R|302|K 0 0 0 0 0.2922874633830891 Q04712 0.02625924535095692 1.0 43.206134559296906 40.0 0.0 no 10050 chrXIII_191007r 26943 essential YML043C 738 + ATCAAGTCTCTTTGGGGCAT I|247|M silent|ATC>ATT|I|247 0 0 0 0 0.2454703076153148 Q04712 0.0 51.255953091602755 45.0 0.0 no 10051 chrXIII_191013r 26945 essential YML043C 732 + GTTCAAATCAAGTCTCTTTG Q|246|E Q|246|* 0 0 0 0 0.9652600387769844 Q04712 0.1519201695919037 40.576508213690936 35.0 0.0 no 10052 chrXIII_191037r 26947 essential YML043C 708 + GCCACATTAATAAGGATCCC silent|GCC>GCG|A|237 silent|GCC>GCT|A|237 A|237|G A|237|V 0 0 0 0 0.4224802477266241 Q04712 0.07577292621135713 0.054741837084293365 47.993673335271474 45.0 0.0 no 10053 chrXIII_191036r 26948 essential YML043C 709 + CCACATTAATAAGGATCCCA T|238|R T|238|I silent|GCC>GCG|A|237 silent|GCC>GCT|A|237 0 0 0 0 -0.4930431583271992 Q04712 0.013197818771004677 0.3089393079280853 45.781806547827216 40.0 0.0 no 10054 chrXIII_191186r 26951 essential YML043C 559 + ACTTCCAATCTATATCTAGA Y|187|* silent|TAC>TAT|Y|187 F|188|L silent|TTC>TTT|F|188 0 0 0 0 -0.11477916222275285 Q04712 0.05778401345014573 41.501343867313096 30.0 0.0 no 10055 chrXIII_191221r 26952 essential YML043C 524 + TCCACTTTTGCATTGTACAA P|176|R P|176|L P|176|A P|176|S 0 0 0 0 0.5421964200007903 Q04712 0.549665093421936 0.3031834065914154 0.8146458268165588 0.99437016248703 45.82947455094325 35.0 0.0 no 10056 chrXIII_191187r 26953 essential YML043C 558 + TACTTCCAATCTATATCTAG Y|187|* silent|TAC>TAT|Y|187 F|188|L silent|TTC>TTT|F|188 0 0 0 0 -1.0870649187969816 Q04712 0.05778401345014573 39.69959730126811 30.0 0.0 no 10057 chrXIII_191220 26954 essential YML043C 528 - TCCTTTGTACAATGCAAAAG K|182|N silent|AAG>AAA|K|182 E|183|Q E|183|K 0 0 0 0 0.004768399884612751 Q04712 0.12971018254756927 0.6123171448707581 0.9351459741592408 39.427442538634686 35.0 0.0 no 10058 chrXIII_191405 26955 essential YML043C 343 - ACTATCTTCCTTGTCTATCC S|121|T S|121|N D|120|H D|120|N 0 0 0 0 -0.6525306370129627 Q04712 0.5119273662567139 0.5976969003677368 0.19727423787117004 0.4957413375377655 50.97592922645492 40.0 0.0 no 10059 chrXIII_191552 26960 essential YML043C 196 - TACTGACCTCCTATATGTGC V|72|L V|72|I R|70|S silent|AGG>AGA|R|70 0 0 0 0 -0.2348015093161419 Q04712 0.3150412142276764 0.17941871285438538 0.024371415376663208 50.04698362940201 45.0 0.0 no 10060 chrXIII_191561r 26961 essential YML043C 184 + ACAGTGAAGCCGGCACATAT N|62|K silent|AAC>AAT|N|62 0 0 0 0 -1.1161167142975477 Q04712 0.8665731549263 50.31598718750166 50.0 0.0 no 10061 chrXIII_212936r 26965 high_effect YML032C 972 + GTACAAAATGAACGTTATAT Q|326|E Q|326|* RAD52 RADiation sensitive 471.0 0 0 0 0 0.5249450570692601 P06778 0.0 32.66493137755896 25.0 0.0 no 10062 chrXIII_212965 26966 high_effect YML032C 946 - TGCAGCCTTAGCTGTAACAA A|322|P A|322|T A|321|P A|321|T RAD52 RADiation sensitive 471.0 0 0 0 0 -1.5973286728500922 P06778 0.0 0.0 0.08335381001234055 0.07081569731235504 49.427719985365506 45.0 0.0 no 10063 chrXIII_213123 26972 high_effect YML032C 788 - ACATAAGAGAATCATCGAGA M|269|I M|269|I RAD52 RADiation sensitive 471.0 0 0 0 0 0.981572610579314 P06778 0.4327955543994904 0.4327955543994904 37.24396796285362 35.0 0.0 no 10064 chrXIII_213156r 26973 high_effect YML032C 752 + ATCTCTCGATGCTTCCAAAC S|252|C S|252|F L|253|V L|253|F RAD52 RADiation sensitive 471.0 0 0 0 0 -1.1022964059556883 P06778 0.061485916376113885 0.07331157475709915 0.2766366004943848 0.06137942150235176 47.435937677381965 45.0 0.0 no 10065 chrXIII_213211 26974 high_effect YML032C 700 - ACTGTTAGCCTCAGCAGGTG S|240|T S|240|N RAD52 RADiation sensitive 471.0 0 0 0 0 -0.5155351723202473 P06778 0.5265893936157227 0.4756048917770386 56.281013874644486 55.00000000000001 0.0 no 10066 chrXIII_213275 26978 high_effect YML032C 636 - ACCAGGTTCTTCGTCGAGTC silent|CTG>CTC|L|218 silent|CTG>CTA|L|218 V|219|L V|219|M RAD52 RADiation sensitive 471.0 0 0 0 1 1.0370064868846165 P06778 0.3116694688796997 0.1096801683306694 55.46577896863072 55.00000000000001 0.0 no 10067 chrXIII_213280 26979 high_effect YML032C 631 - GTTCTTCGTCGAGTCGGGAT K|216|N silent|AAG>AAA|K|216 silent|ACG>ACC|T|215 silent|ACG>ACA|T|215 RAD52 RADiation sensitive 471.0 0 1 0 0 -0.16409871492046985 P06778 0.5062562823295593 54.269851115989006 55.00000000000001 0.0 no 10068 chrXIII_213402r 26981 high_effect YML032C 506 + AAACAATTTGTTTAGGCCAA N|170|K silent|AAC>AAT|N|170 RAD52 RADiation sensitive 471.0 0 0 0 0 -0.03624575693420457 P06778 0.18387585878372192 39.574619424642954 30.0 0.0 no 10069 chrXIII_213514r 26983 high_effect YML032C 394 + CCTTGAAAAGATCTTTGAGA silent|GCC>GCG|A|132 silent|GCC>GCT|A|132 RAD52 RADiation sensitive 471.0 0 0 0 0 -1.5840073682280629 P06778 39.13715488413096 35.0 0.0 no 10070 chrXIII_213526 26984 high_effect YML032C 385 - TCTTTTCAAGGCATCCGTAA R|135|T R|135|K L|133|F silent|TTG>TTA|L|133 RAD52 RADiation sensitive 471.0 0 0 0 0 -6.2288002059241725 P06778 0.0 0.0 0.023765474557876587 1.5780999660491943 0.706000030040741 2.381999969482422 47.45633102732558 40.0 0.0 yes 10071 chrXIII_213553 26986 high_effect YML032C 358 - TTTCTTGGCCCTTTCGAAAG K|125|N silent|AAG>AAA|K|125 RAD52 RADiation sensitive 471.0 0 1 0 0 -2.3271210307168086 P06778 0.013816475868225098 1.0322999954223633 49.07355986065266 45.0 0.0 yes 10072 chrXIII_212970r 26987 high_effect YML032C 938 + AATCACCTTTGTTACAGCTA I|314|M silent|ATC>ATT|I|314 T|315|S T|315|I RAD52 RADiation sensitive 471.0 0 0 0 0 0.7070094153886111 P06778 0.07371223717927933 0.8211556077003479 0.19218316674232486 45.609506031948 35.0 0.0 no 10073 chrXIII_213580 26988 high_effect YML032C 331 - TTTCCGTCTTTCGTTCTCCA silent|CGG>CGC|R|116 silent|CGG>CGA|R|116 R|116|P R|116|Q RAD52 RADiation sensitive 471.0 0 0 0 1 0.21322647936245773 P06778 0.13992930948734286 0.15139786899089813 -0.6516000032424927 -0.6575999855995178 55.8791624981464 45.0 0.0 no 10074 chrXIII_213632r 26992 high_effect YML032C 276 + GTTCGTGTTACGTTGACTAG R|94|G R|94|C RAD52 RADiation sensitive 471.0 0 0 0 0 0.05110872447480125 P06778 0.0 0.0 2.115499973297119 0.8190000057220459 46.48073948409194 45.0 0.0 no 10075 chrXIII_213818 26996 high_effect YML032C 93 - ACTCTCTTGGAGATATACTC R|37|T R|37|K V|38|L V|38|I RAD52 RADiation sensitive 471.0 0 0 0 0 -3.5336856549456765 P06778 0.0 0.0 0.4060263633728027 0.5861109495162964 44.35110390606292 40.0 0.0 yes 10076 chrXIII_213841 26997 high_effect YML032C 70 - TCCTAATTTCTTGTCCAATT G|30|R G|30|R G|30|A G|30|E RAD52 RADiation sensitive 471.0 0 0 0 0 -0.8319700490143351 P06778 0.0 0.0 0.0 0.0 44.770698210122994 30.0 0.0 no 10077 chrXIII_214311r 27000 essential YML031W 125 - GCAGTGAAATCACCACAGTT silent|CTG>CTC|L|48 silent|CTG>CTA|L|48 NDC1 Nuclear Division Cycle 655.0 0 0 0 0 -2.071230630981878 P32500 47.41750163131389 45.0 1.0 yes 10078 chrXIII_214351r 27003 essential YML031W 165 - GCCAATGCCAGTTCCCATAA L|61|F silent|TTG>TTA|L|61 A|62|P A|62|T NDC1 Nuclear Division Cycle 655.0 0 0 0 0 -1.0757940013773513 P32500 0.9587849974632264 0.9573720097541808 0.9523990154266356 0.38468575477600103 0.21414342522621155 0.4536943137645722 55.29024820690404 50.0 1.0 no 10079 chrXIII_214439 27004 essential YML031W 250 + ACATGCATGTAAAGAATTTT Y|84|* silent|TAC>TAT|Y|84 H|86|D H|86|Y NDC1 Nuclear Division Cycle 655.0 0 0 0 0 0.2032598706324716 P32500 0.9473130106925964 0.9489949941635132 0.0 0.0 35.80867689757781 25.0 1.0 no 10080 chrXIII_214545 27006 essential YML031W 356 + CATCCTTTTATCATTCGTAC I|120|M silent|ATC>ATT|I|120 L|121|V L|121|F NDC1 Nuclear Division Cycle 655.0 0 0 0 0 0.014844771175693581 P32500 0.9598389863967896 0.9512209892272948 0.9587849974632264 0.0806286484003067 0.2554352581501007 0.26596251130104065 44.59284026026086 35.0 1.0 no 10081 chrXIII_214650r 27009 essential YML031W 464 - CGTCAGTGACATGATGTTGT D|161|H D|161|N NDC1 Nuclear Division Cycle 655.0 0 0 0 0 -3.7833031338442176 P32500 0.9486550092697144 0.956179976463318 0.0 0.0 47.427954247734995 45.0 1.0 yes 10082 chrXIII_214689 27010 essential YML031W 500 + CAACTGCGAAAACTTTTTCC N|168|K silent|AAC>AAT|N|168 C|169|W silent|TGC>TGT|C|169 NDC1 Nuclear Division Cycle 655.0 0 0 0 0 -1.810711735615228 P32500 0.9439849853515624 0.9286419749259948 0.9695805311203004 0.08207561075687407 41.338156202454634 40.0 1.0 no 10083 chrXIII_214714r 27014 essential YML031W 528 - CGCTCTAATACGTAGTCTTG E|182|D silent|GAG>GAA|E|182 E|182|Q E|182|K NDC1 Nuclear Division Cycle 655.0 0 0 0 0 -2.2818823967596726 P32500 0.94931298494339 0.956179976463318 0.9475290179252625 0.6266992092132568 0.5700432658195496 0.9220293760299684 45.382931423884095 45.0 1.0 yes 10084 chrXIII_215027 27020 essential YML031W 838 + CTGCAGACAAGCCATTTACT A|281|G A|281|V NDC1 Nuclear Division Cycle 655.0 0 0 0 0 -0.2416680316612458 P32500 0.9484469890594482 0.9504740238189696 0.04671832174062729 0.01684113591909409 48.53757016271004 45.0 1.0 no 10085 chrXIII_215043 27022 essential YML031W 854 + TACTAGGTTGACTGCCTACC T|286|S T|286|I NDC1 Nuclear Division Cycle 655.0 0 0 0 0 0.5003675894088169 P32500 0.9491789937019348 0.9472420215606691 0.05122236534953117 0.03676058724522591 52.29785833885308 50.0 1.0 no 10086 chrXIII_215123r 27026 essential YML031W 937 - ACCACTACTGCTTCTGAACT G|319|R G|319|S G|319|A G|319|D NDC1 Nuclear Division Cycle 655.0 0 0 0 0 -1.0740649235964914 P32500 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.3087001740932465 0.8338208794593811 1.0 0.35502931475639343 49.25143545490538 45.0 1.0 no 10087 chrXIII_215318r 27029 essential YML031W 1132 - GTTCCCAAAGAGTCTTTCGT silent|GGG>GGC|G|383 silent|GGG>GGA|G|383 G|383|A G|383|E NDC1 Nuclear Division Cycle 655.0 0 0 0 0 -1.4309049311358717 P32500 0.9499930143356324 0.9438679814338684 0.14983056485652926 0.02564658410847187 50.95057290465985 45.0 1.0 no 10088 chrXIII_215345 27030 essential YML031W 1156 + CCTCTATGATGGCGCCATTA S|387|C S|387|F silent|CCC>CCG|P|386 silent|CCC>CCT|P|386 NDC1 Nuclear Division Cycle 655.0 0 0 0 0 0.023858196408106186 P32500 0.945252001285553 0.9294660091400146 0.057842254638671875 0.07299996167421341 53.68006724370389 50.0 1.0 no 10089 chrXIII_215345r 27031 essential YML031W 1159 - CCGTAATGGCGCCATCATAG R|393|P R|393|Q NDC1 Nuclear Division Cycle 655.0 0 0 0 0 -5.334663791293618 P32500 0.9099509716033936 0.949662983417511 0.32786574959754944 0.6366640329360962 51.89645661400362 55.00000000000001 1.0 yes 10090 chrXIII_215392r 27033 essential YML031W 1206 - GTTCTTACCCTCAGCCTGTT R|408|T R|408|K NDC1 Nuclear Division Cycle 655.0 0 1 0 0 -2.202251484567254 P32500 0.932735025882721 0.955805003643036 0.5446826815605164 1.0 59.76395437132891 50.0 1.0 yes 10091 chrXIII_215522r 27035 essential YML031W 1336 - GGTCATAAATGTTGTTTCGT M|451|I M|451|I NDC1 Nuclear Division Cycle 655.0 0 0 0 0 -0.7685283169770052 P32500 0.9553959965705872 0.9553959965705872 0.5030755996704102 0.5030755996704102 43.36632433625431 35.0 1.0 no 10092 chrXIII_227513r 27039 essential YML023C 1129 + TTGCAGATGATGTTATCCAG A|378|G A|378|V 0 0 0 0 1.0207290289867332 Q03718 0.4029077291488648 0.3502917289733887 45.35952645215286 40.0 0.0 no 10093 chrXIII_227523 27040 essential YML023C 1122 - ACATCATCTGCAACTATTCT V|381|L V|381|I D|380|H D|380|N 0 0 0 0 -0.06601200440374419 Q03718 1.0 0.7386969327926636 0.07952026277780533 0.28604984283447266 44.27858037986157 35.0 0.0 no 10094 chrXIII_227612r 27041 essential YML023C 1030 + CACAAAAATCATTAGCTTTG Q|345|E Q|345|* 0 0 0 0 0.9420295035006416 Q03718 0.3750689923763275 35.029203444633595 30.0 0.0 no 10095 chrXIII_227945r 27047 essential YML023C 697 + TCCTATCAAGCCATGAGATT L|234|V silent|CTA>TTA|L|234 F|233|L silent|TTC>TTT|F|233 0 0 0 0 -0.6097794423819499 Q03718 0.302756130695343 0.04474057629704475 47.65689695920036 40.0 0.0 no 10096 chrXIII_228066r 27049 essential YML023C 576 + GAGCAAAGAAATACCATATT Q|194|E Q|194|* 0 0 0 0 0.6826603600733772 Q03718 0.1060214787721634 36.2179476883457 30.0 0.0 no 10097 chrXIII_228093 27050 essential YML023C 552 - CAACTAATATACGACCTGTA S|190|T S|190|N 0 0 0 0 0.30132078861869405 Q03718 0.4201807081699371 0.06211679801344872 39.516319977663564 35.0 0.0 no 10098 chrXIII_228107r 27051 essential YML023C 535 + AAACTTTTAAAAATCCTTAC T|180|S T|180|I 0 0 0 0 0.3721845339366513 Q03718 0.8303845524787903 0.12477800250053404 31.0890998095278 20.0 0.0 no 10099 chrXIII_228356 27056 essential YML023C 289 - TCTCCTACTTAAAGTTTCCC R|102|S silent|AGG>AGA|R|102 R|103|T R|103|K 0 0 0 0 0.31632419902787423 Q03718 0.04805392026901245 0.014111604541540148 0.2093128710985184 48.85414338411806 40.0 0.0 no 10100 chrXIII_228415r 27057 essential YML023C 227 + GACTTTATCTGAATATTATA T|77|S T|77|I 0 0 0 0 0.899004313790953 Q03718 0.0 0.0 33.67209342719292 20.0 0.0 no 10101 chrXIII_228481r 27059 essential YML023C 161 + GTTCGGCAAATCTCACAATT F|55|L silent|TTC>TTT|F|55 silent|GGC>GGG|G|56 silent|GGC>GGT|G|56 0 0 0 0 0.4901338709181957 Q03718 0.6184523105621338 44.14949151813454 40.0 0.0 no 10102 chrXIII_228574r 27060 essential YML023C 68 + ACTCACTGAGAAACATCTAT silent|CTC>CTG|L|24 silent|CTC>CTT|L|24 L|24|V L|24|F 0 0 0 0 -0.25909268236894845 Q03718 0.3523496687412262 0.036901168525218964 39.55327988968708 35.0 0.0 no 10103 chrXIII_242278 27062 essential YML015C 732 - TCATCGTCGAAGTAGAAATC E|251|Q E|251|K D|250|H D|250|N TAF11 TATA binding protein-Associated Factor 346.0 0 0 0 0 -0.7008217008318236 Q04226 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 39.584155873866855 40.0 0.0 no 10104 chrXIII_242388 27065 essential YML015C 622 - TTTCAATTTATAGCCTATTT L|213|F silent|TTG>TTA|L|213 TAF11 TATA binding protein-Associated Factor 346.0 0 0 0 0 0.3672123486017272 Q04226 0.9587849974632264 0.0523335263133049 39.2231501857799 20.0 0.0 no 10105 chrXIII_242448 27066 essential YML015C 562 - CCACTTATTCTTCACAATCA K|193|N silent|AAG>AAA|K|193 W|194|S W|194|* TAF11 TATA binding protein-Associated Factor 346.0 0 0 0 0 -0.4968581978203627 Q04226 0.9355990290641784 0.8858469724655151 0.017696958035230637 0.3753990828990936 44.503375825429366 35.0 0.0 no 10106 chrXIII_242801 27072 essential YML015C 209 - GCTGATTTATCCTGGTTTTC Q|76|H silent|CAG>CAA|Q|76 TAF11 TATA binding protein-Associated Factor 346.0 0 0 0 0 -0.04283303805493233 Q04226 0.9570760130882264 0.15068121254444122 49.51574256728134 40.0 0.0 no 10107 chrXIII_247715r 27077 essential YML010W 41 - GATCAGCAAATTGTTGATCA D|20|H D|20|N A|19|P A|19|T SPT5 SuPpressor of Ty's 1063.0 0 0 0 0 0.8449177593179653 P27692 0.9486550092697144 0.956179976463318 0.9573720097541808 0.9523990154266356 41.239565305058534 35.0 1.0 no 10108 chrXIII_247724 27078 essential YML010W 47 + ACAATTTGCTGATCCCGTAG Q|17|E Q|17|* SPT5 SuPpressor of Ty's 1063.0 0 0 0 0 -1.062143900500985 P27692 0.9590039849281312 48.389396499649074 45.0 1.0 no 10109 chrXIII_247749r 27079 essential YML010W 75 - TCTTTAGTGTCAGTTGACTG D|32|H D|32|N SPT5 SuPpressor of Ty's 1063.0 0 1 0 0 -0.8656333590907157 P27692 0.9486550092697144 0.956179976463318 45.85423433759728 40.0 1.0 no 10110 chrXIII_247816r 27080 essential YML010W 142 - ACGTTCTGTACTTTCCGTTG R|54|P R|54|H E|53|Q E|53|K SPT5 SuPpressor of Ty's 1063.0 0 1 0 0 -0.7063175400589505 P27692 0.9099509716033936 0.9570810198783876 0.956179976463318 0.9475290179252625 50.13141892242612 45.0 1.0 no 10111 chrXIII_247851 27081 essential YML010W 174 + AGCAATATTCCCCCTTTAGA S|59|R silent|AGC>AGT|S|59 SPT5 SuPpressor of Ty's 1063.0 0 1 0 0 0.048783477137058766 P27692 0.9417110085487366 51.55924062264796 40.0 1.0 no 10112 chrXIII_247852 27082 essential YML010W 175 + GCAATATTCCCCCTTTAGAT S|59|R silent|AGC>AGT|S|59 SPT5 SuPpressor of Ty's 1063.0 0 1 0 0 -0.2274864073336011 P27692 0.9417110085487366 51.43978332133196 40.0 1.0 no 10113 chrXIII_247863r 27083 essential YML010W 189 - TCTTTTTCTTCCCCATCTAA E|70|Q E|70|K SPT5 SuPpressor of Ty's 1063.0 0 1 0 0 -0.13005878502742196 P27692 0.956179976463318 0.9475290179252625 50.762631267729944 35.0 1.0 no 10114 chrXIII_247892 27084 essential YML010W 215 + ATCTGAGCCACAGCAACCTG S|73|C S|73|F SPT5 SuPpressor of Ty's 1063.0 0 1 0 0 0.7689708020203531 P27692 0.945252001285553 0.9294660091400146 53.22933224488895 55.00000000000001 1.0 no 10115 chrXIII_247908r 27085 essential YML010W 234 - GCCGTTTCTGCATTATCCTC silent|ACG>ACC|T|84 silent|ACG>ACA|T|84 A|85|P A|85|T SPT5 SuPpressor of Ty's 1063.0 0 0 0 0 -4.055802608611368 P27692 0.9573720097541808 0.9523990154266356 56.358071543495214 50.0 1.0 yes 10116 chrXIII_247979r 27089 essential YML010W 305 - AATCCGTATTCAAAGTTGCT D|108|H D|108|N silent|ACG>ACC|T|107 silent|ACG>ACA|T|107 SPT5 SuPpressor of Ty's 1063.0 0 0 0 0 0.6744655349453976 P27692 0.9486550092697144 0.956179976463318 43.58929477608939 35.0 1.0 no 10117 chrXIII_248170 27091 essential YML010W 493 + ACGATGAAGCCCCAACTAAA D|165|E silent|GAC>GAT|D|165 SPT5 SuPpressor of Ty's 1063.0 0 0 0 0 1.3035140684389572 P27692 0.9532920122146606 45.35493704804525 45.0 1.0 no 10118 chrXIII_248180r 27093 essential YML010W 506 - CCTGACGACGCCTTTTAGTT Q|175|H silent|CAG>CAA|Q|175 R|174|P R|174|H SPT5 SuPpressor of Ty's 1063.0 0 0 0 0 0.1574959188829451 P27692 0.9570760130882264 0.9099509716033936 0.9570810198783876 0.12876375019550326 0.008876005187630653 0.009750396944582462 52.54035153327794 50.0 1.0 no 10119 chrXIII_248181r 27094 essential YML010W 507 - TCCTGACGACGCCTTTTAGT Q|175|H silent|CAG>CAA|Q|175 E|176|Q E|176|K SPT5 SuPpressor of Ty's 1063.0 0 0 0 0 -0.3202620211329293 P27692 0.9570760130882264 0.956179976463318 0.9475290179252625 0.12876375019550326 0.5215610265731812 1.0 53.35859249195619 50.0 1.0 no 10120 chrXIII_248303r 27097 essential YML010W 629 - CGTCATCTTCATCATCACCA D|216|H D|216|N D|215|H D|215|N SPT5 SuPpressor of Ty's 1063.0 0 1 0 0 -0.09657377592070462 P27692 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.12711264193058014 0.4668116569519043 0.1675431728363037 0.4263845980167389 50.92290255197168 45.0 1.0 no 10121 chrXIII_248498r 27099 essential YML010W 824 - CACTTGGTAGGAGAAACCTC S|281|T S|281|N SPT5 SuPpressor of Ty's 1063.0 0 0 0 0 -1.3104379661311292 P27692 0.9512869715690612 0.9536849856376648 0.14431583881378174 0.011600421741604805 46.402561554387376 50.0 1.0 no 10122 chrXIII_248556r 27103 essential YML010W 882 - ATCAATTCCTTTTCTTTACC L|300|F silent|TTG>TTA|L|300 SPT5 SuPpressor of Ty's 1063.0 0 0 0 0 0.5084702144952477 P27692 0.9587849974632264 0.0534144788980484 8.569675445556639 44.74765823943893 30.0 1.0 no 10123 chrXIII_248693r 27106 essential YML010W 1019 - TTTCAATAACGGATTGCTTA E|346|Q E|346|K SPT5 SuPpressor of Ty's 1063.0 0 1 0 0 0.30857979446925965 P27692 0.956179976463318 0.9475290179252625 0.5922237634658813 0.919542133808136 39.46324898563847 30.0 1.0 no 10124 chrXIII_248796r 27107 essential YML010W 1122 - GCAACATCATCAGATTTGTT A|381|P A|381|T V|380|L V|380|I SPT5 SuPpressor of Ty's 1063.0 0 0 0 0 -2.5328754679814915 P27692 0.9573720097541808 0.9523990154266356 0.9539830088615416 0.9574310183525084 0.19661681354045868 0.4601671993732453 0.1855514943599701 0.263538271188736 43.55071122861313 35.0 1.0 yes 10125 chrXIII_248832 27109 essential YML010W 1155 + AGCTACGTTCGTATTAAGAG S|386|R silent|AGC>AGT|S|386 Y|387|* silent|TAC>TAT|Y|387 SPT5 SuPpressor of Ty's 1063.0 0 0 0 0 -0.4482725705149092 P27692 0.9417110085487366 0.12183690071105956 0.5588939785957336 42.37920108781253 40.0 1.0 no 10126 chrXIII_248915 27110 essential YML010W 1238 + GCTGAAAATTGTTCCTCGTC L|414|V silent|CTG>TTG|L|414 SPT5 SuPpressor of Ty's 1063.0 0 0 0 0 0.267411375968317 P27692 0.9512209892272948 1.0 2.7264060974121094 46.68596987477378 45.0 1.0 no 10127 chrXIII_249055 27111 essential YML010W 1378 + ACCAAGCTAACCTGTACAAA Q|461|E Q|461|* D|460|E silent|GAC>GAT|D|460 SPT5 SuPpressor of Ty's 1063.0 0 0 0 0 0.1604943649529551 P27692 0.9590039849281312 0.9532920122146606 1.0 0.22002431750297546 0.7146459817886353 2.215748071670532 43.650787838535564 40.0 1.0 no 10128 chrXIII_249056 27112 essential YML010W 1379 + CCAAGCTAACCTGTACAAAA Q|461|E Q|461|* A|462|G A|462|V SPT5 SuPpressor of Ty's 1063.0 0 0 0 0 -0.2749230747313557 P27692 0.9590039849281312 0.9484469890594482 0.9504740238189696 1.0 0.3626273274421692 0.2778317928314209 0.7146459817886353 0.5389000177383423 0.8062340021133423 41.932602850403036 40.0 1.0 no 10129 chrXIII_249160r 27115 essential YML010W 1486 - CACAGTTGGCTGAATATTTT V|502|L V|502|M SPT5 SuPpressor of Ty's 1063.0 0 0 0 0 1.0646108052285297 P27692 0.9539830088615416 0.9587630033493042 1.0 0.024689920246601105 -0.2953299880027771 -0.3869419991970062 42.89695266183179 35.0 1.0 no 10130 chrXIII_249288 27121 essential YML010W 1611 + GATCGTATCGAAGTTCTAAA R|539|G R|539|C SPT5 SuPpressor of Ty's 1063.0 0 0 0 0 1.107890176074509 P27692 0.8994590044021606 0.8926740288734436 0.19645459949970245 0.042779501527547836 1.9917199611663816 0.698639988899231 38.856255210943395 35.0 1.0 no 10131 chrXIII_248533r 27122 essential YML010W 859 - TCTGCAGCGCACACCCCAAA R|293|T R|293|K C|292|S C|292|Y SPT5 SuPpressor of Ty's 1063.0 0 0 0 0 -1.8230348564195071 P27692 0.932735025882721 0.955805003643036 0.9421560168266296 0.9290120005607604 0.12871919572353366 0.7747759222984314 0.01868230663239956 0.002420342760160565 0.4043219983577728 17.68910026550293 57.41996900259238 60.0 1.0 no 10132 chrXIII_249450 27123 essential YML010W 1773 + GTCATCAATGGTGAACATCA silent|GTC>GTG|V|592 silent|GTC>GTT|V|592 I|593|M silent|ATC>ATT|I|593 SPT5 SuPpressor of Ty's 1063.0 0 0 0 0 0.13796139971345686 P27692 0.9598389863967896 0.01079458836466074 0.16944000124931335 43.4509176650841 40.0 1.0 no 10133 chrXIII_249675 27124 essential YML010W 1998 + TTCAAGGTTATTGATGAAAC F|667|L silent|TTC>TTT|F|667 SPT5 SuPpressor of Ty's 1063.0 0 0 0 0 1.0617990513290474 P27692 0.9387490153312684 0.8882603645324707 35.288809555208786 30.0 1.0 no 10134 chrXIII_249920 27125 essential YML010W 2243 + CCCTAGTAACGTTGAGGCCG P|749|R P|749|L P|749|A P|749|S SPT5 SuPpressor of Ty's 1063.0 0 0 0 0 0.6632949433630148 P27692 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.5275513529777527 0.364321231842041 1.0 0.9600019454956056 54.64507284821071 60.0 1.0 no 10135 chrXIII_250044r 27129 essential YML010W 2370 - CGACCTCCTCTGGACTGGAT G|796|A G|796|D G|796|R G|796|S SPT5 SuPpressor of Ty's 1063.0 0 0 0 0 -1.83827240531924 P27692 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.0 0.0 0.0 0.0 56.26108063128294 60.0 1.0 no 10136 chrXIII_250049r 27130 essential YML010W 2375 - CTTCACGACCTCCTCTGGAC E|798|Q E|798|K R|797|P R|797|H SPT5 SuPpressor of Ty's 1063.0 0 0 0 0 -1.8850790720845845 P27692 0.956179976463318 0.9475290179252625 0.9099509716033936 0.9570810198783876 0.019449740648269653 0.01566385105252266 0.01777433417737484 0.02027174644172192 55.921746806741574 60.0 1.0 no 10137 chrXIII_250045r 27131 essential YML010W 2371 - ACGACCTCCTCTGGACTGGA R|797|P R|797|H G|796|A G|796|D SPT5 SuPpressor of Ty's 1063.0 0 0 0 0 -2.4081207307661647 P27692 0.9099509716033936 0.9570810198783876 0.9499930143356324 0.9446240067481996 0.01777433417737484 0.02027174644172192 0.0 0.0 56.75182957488744 60.0 1.0 yes 10138 chrXIII_250054r 27132 essential YML010W 2380 - TGCAACTTCACGACCTCCTC A|800|P A|800|T V|799|L V|799|I SPT5 SuPpressor of Ty's 1063.0 0 1 0 0 -2.9108813850704065 P27692 0.9573720097541808 0.9523990154266356 0.9539830088615416 0.9574310183525084 0.1483716517686844 0.7144438624382019 0.1880842447280884 0.10140078514814377 53.75201271570552 55.00000000000001 1.0 yes 10139 chrXIII_252116r 27133 high_effect YML008C 852 + CCTTGGTATTACCCATTAAC P|285|R P|285|L ERG6 ERGosterol biosynthesis 383.0 0 0 0 0 0.1005145228789816 P25087 0.9432820081710817 0.9430609941482544 0.0021915677934885025 0.002993804169818759 47.16995729072056 40.0 0.0 no 10140 chrXIII_252133r 27135 high_effect YML008C 835 + ACAATGATGATGAAATCCCT D|279|E silent|GAC>GAT|D|279 ERG6 ERGosterol biosynthesis 383.0 0 0 0 0 0.0233448768391265 P25087 0.9532920122146606 1.0 40.89991926738286 35.0 0.0 no 10141 chrXIII_252141 27136 high_effect YML008C 830 - TTTCATCATCATTGTCCGCC E|283|Q E|283|K D|282|H D|282|N ERG6 ERGosterol biosynthesis 383.0 0 0 0 0 -0.7365762379122971 P25087 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.5901069045066833 0.8206421732902527 0.03535829856991768 0.2457485347986221 53.03745607100319 45.0 0.0 no 10142 chrXIII_252248r 27142 high_effect YML008C 720 + ATCGCTTATGAAATTGAACT I|241|M silent|ATC>ATT|I|241 A|242|G A|242|V ERG6 ERGosterol biosynthesis 383.0 0 1 0 0 -1.1746378958590555 P25087 0.9598389863967896 0.9484469890594482 0.9504740238189696 0.0063221477903425685 0.10167142003774644 0.09731458872556686 37.58490594444851 30.0 0.0 no 10143 chrXIII_252465r 27146 high_effect YML008C 503 + TGACCAAATGGACTTTGTAA D|169|E silent|GAC>GAT|D|169 Q|170|E Q|170|* ERG6 ERGosterol biosynthesis 383.0 0 0 0 0 0.6718057070575221 P25087 0.9532920122146606 0.9590039849281312 0.7786682844161987 0.4806089401245117 -0.0198999997228384 40.157536905958295 35.0 0.0 no 10144 chrXIII_252477r 27147 high_effect YML008C 491 + ATACAATTTGAGTGACCAAA Y|165|* silent|TAC>TAT|Y|165 ERG6 ERGosterol biosynthesis 383.0 0 0 0 0 0.7225674732501255 P25087 37.50743340645687 30.0 0.0 no 10145 chrXIII_252519r 27148 high_effect YML008C 449 + TAACGATTACCAAATTGCCA N|151|K silent|AAC>AAT|N|151 ERG6 ERGosterol biosynthesis 383.0 0 0 0 0 0.29849357804199395 P25087 0.9439849853515624 0.00477857980877161 41.78255362324063 35.0 0.0 no 10146 chrXIII_252572 27149 high_effect YML008C 399 - AATCTTGCAATCTCTCTTGC R|139|T R|139|K ERG6 ERGosterol biosynthesis 383.0 0 0 0 0 0.3440743351112142 P25087 0.932735025882721 0.955805003643036 0.20105500519275665 0.7821083664894104 46.59294947318296 40.0 0.0 no 10147 chrXIII_252573 27150 high_effect YML008C 398 - ATCTTGCAATCTCTCTTGCT R|139|T R|139|K A|138|P A|138|T ERG6 ERGosterol biosynthesis 383.0 0 0 0 0 1.047889671655155 P25087 0.932735025882721 0.955805003643036 0.9573720097541808 0.9523990154266356 0.20105500519275665 0.7821083664894104 0.01115943118929863 0.1579664647579193 50.221535872417796 40.0 0.0 no 10148 chrXIII_252598r 27152 high_effect YML008C 370 + TCGACGTTGGTTGTGGTGTT silent|CTC>CTG|L|124 silent|CTC>CTT|L|124 D|125|E silent|GAC>GAT|D|125 ERG6 ERGosterol biosynthesis 383.0 0 0 0 0 -1.0171183091409235 P25087 0.9532920122146606 0.0 52.78338567873476 50.0 0.0 no 10149 chrXIII_252808 27156 high_effect YML008C 163 - ACGTTCTTCGGCATCTTTAT R|61|P R|61|H E|60|Q E|60|K ERG6 ERGosterol biosynthesis 383.0 0 1 0 0 0.9027574684475616 P25087 0.9099509716033936 0.9570810198783876 0.956179976463318 0.9475290179252625 0.24716633558273315 0.1287805140018463 0.08844126760959625 0.2760157883167267 49.13318332786714 40.0 0.0 no 10150 chrXIII_252855 27157 high_effect YML008C 116 - ACTTCTGAACGGCTTCCTTT K|45|N silent|AAG>AAA|K|45 Q|44|H silent|CAG>CAA|Q|44 ERG6 ERGosterol biosynthesis 383.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.4563341618366469 P25087 0.9355990290641784 0.9570760130882264 0.4368032217025757 0.06588897109031677 51.09828388183979 45.0 0.0 no 10151 chrXIII_269563r 27158 essential YMR001C 1551 + GTCGACTACTCCAACAAACA silent|GTC>GTG|V|518 silent|GTC>GTT|V|518 D|519|E silent|GAC>GAT|D|519 0 0 0 0 -1.0948662187349845 P32562 0.0 44.27320816663854 45.0 0.0 no 10152 chrXIII_269585r 27160 essential YMR001C 1529 + CCCAATGATAGTTACCAAGT P|511|R P|511|L P|511|A P|511|S 0 0 0 0 -4.996838195465054 P32562 0.14550445973873138 0.07426183670759201 0.2741309106349945 0.3864968419075012 46.21407765511651 40.0 0.0 yes 10153 chrXIII_269859 27165 essential YMR001C 1258 - TTTCTGTTTCGTCCCGCCAG Q|425|H silent|CAG>CAA|Q|425 0 1 0 0 0.5538917467123105 P32562 0.05512939766049385 58.83003632127793 55.00000000000001 0.0 no 10154 chrXIII_269871r 27166 essential YMR001C 1243 + CACATTCTTTATCCCCTGGC H|416|D H|416|Y S|417|C S|417|F 0 1 0 0 -0.7574194633280447 P32562 0.6267648339271545 0.10478582233190536 0.1482115536928177 0.849406898021698 55.62482582181207 50.0 0.0 no 10155 chrXIII_269872r 27168 essential YMR001C 1242 + CCACATTCTTTATCCCCTGG H|416|D H|416|Y P|415|R P|415|L 0 1 0 0 0.2361376705201778 P32562 0.6267648339271545 0.10478582233190536 0.01856265403330326 0.020687585696578026 55.499841307717645 50.0 0.0 no 10156 chrXIII_269875r 27169 essential YMR001C 1239 + TTACCACATTCTTTATCCCC P|415|A P|415|S P|415|R P|415|L 0 1 0 0 -1.6918420099225733 P32562 0.07993375509977341 0.09019409120082857 0.01856265403330326 0.020687585696578026 51.66951284936811 40.0 0.0 no 10157 chrXIII_270055 27170 essential YMR001C 1062 - TCAGGAATATCCTCAAAATT E|361|Q E|361|K 0 1 0 0 0.19003918853605006 P32562 0.6926647424697876 0.9585564136505128 38.159369418267204 30.0 0.0 no 10158 chrXIII_270065r 27171 essential YMR001C 1049 + GTCAGAAGCACCAAATTTTG S|351|* S|351|L 0 0 0 0 0.4066392923121997 P32562 0.07799225300550461 42.249260480279865 40.0 0.0 no 10159 chrXIII_270092r 27174 essential YMR001C 1022 + CCCACCATCTATTCCTTCGA P|342|R P|342|L P|342|A P|342|S 0 0 0 0 -1.323136735211944 P32562 0.0 0.0 0.0 0.0 55.97750628622919 50.0 0.0 no 10160 chrXIII_270162r 27176 essential YMR001C 952 + TATCCTTAGATCCAATAGAA S|319|C S|319|F silent|TCC>TCG|S|319 silent|TCC>TCT|S|319 0 0 0 0 -0.3606201032926405 P32562 0.09221290051937103 0.15906791388988495 40.240241145851606 30.0 0.0 no 10161 chrXIII_270307r 27179 essential YMR001C 807 + ATGCTTTATGCTTTGTTGAT L|271|V L|271|F 0 0 0 0 0.8508420772789562 P32562 0.5517387986183167 0.06885947287082672 44.6174149558982 30.0 0.0 no 10162 chrXIII_270342r 27180 essential YMR001C 772 + ATTCATTTGAAGTAGATATT S|259|* S|259|L 0 0 0 0 -0.2353738698592427 P32562 0.0 34.66434232925428 20.0 0.0 no 10163 chrXIII_270415r 27183 essential YMR001C 699 + GAACGTAAATACACCATATG R|235|G R|235|C 0 1 0 0 -0.223211730242872 P32562 0.013793935999274254 0.0018605603836476805 -0.350600004196167 0.1379999965429306 36.75330284114108 35.0 0.0 no 10164 chrXIII_270466r 27184 essential YMR001C 648 + AACTTAAAGATTGGTGACTT N|217|K silent|AAC>AAT|N|217 0 0 0 0 -0.18960207399260146 P32562 0.03176252543926239 37.06761470818191 30.0 0.0 no 10165 chrXIII_270388 27185 essential YMR001C 729 - ACTTCAGGTGCGATGTAATT V|250|L V|250|M E|249|Q E|249|K 0 0 0 0 -4.7838141363367805 P32562 0.0 0.0 0.0 0.0 1.1512000560760498 0.10580000281333923 45.81939040037406 40.0 0.0 yes 10166 chrXIII_270475r 27186 essential YMR001C 639 + TCAAACTATAACTTAAAGAT S|214|* S|214|L N|215|K silent|AAC>AAT|N|215 0 0 0 0 -0.8309641589155026 P32562 0.10662367194890976 0.2421003580093384 29.71999402110185 20.0 0.0 no 10167 chrXIII_270689r 27190 essential YMR001C 425 + TCAGTTTATTGATTGTTTTG Q|143|E Q|143|* 0 0 0 0 -0.08791107434304235 P32562 0.9109633564949036 0.645799994468689 38.67260396186009 25.0 0.0 no 10168 chrXIII_270700 27191 essential YMR001C 417 - TCAATAAACTGAACGATATT D|146|H D|146|N 0 0 0 0 1.2111823321652164 P32562 0.007141600362956523 0.02080082520842552 5.08080005645752 -0.16539999842643738 32.49014932591274 25.0 0.0 no 10169 chrXIII_270866 27192 essential YMR001C 251 - CTTCACCTAAAAAATGACCT E|90|Q E|90|K G|89|A G|89|D 0 0 0 0 -0.9096580751504764 P32562 0.0 0.0 0.0 0.0 39.562854477006 35.0 0.0 no 10170 chrXIII_270836r 27193 essential YMR001C 278 + TGCTCGCTGTTTCCAAATTA A|94|G A|94|V R|95|G R|95|C 0 0 0 0 0.2961120452435365 P32562 0.0 0.0 0.0 0.0 48.09264464504047 40.0 0.0 no 10171 chrXIII_271029 27194 essential YMR001C 88 - TTCTTTTCCTACGAGGTCTG E|36|Q E|36|K 0 0 0 0 -0.5834547238720973 P32562 0.3407575190067291 0.43547385931015015 50.06265738630043 45.0 0.0 no 10172 chrXIII_271046 27195 essential YMR001C 71 - CTGCGGTATTTCCCTTTATT A|30|P A|30|T 0 1 0 0 0.7125865450671556 P32562 51.43913231992435 40.0 0.0 no 10173 chrXIII_271047 27196 essential YMR001C 70 - TGCGGTATTTCCCTTTATTG A|30|P A|30|T 0 1 0 0 0.33559918577129705 P32562 49.61477354385676 40.0 0.0 no 10174 chrXIII_276135 27197 essential YMR005W 90 + CCAGCATTTAATTTGTCACC P|31|R P|31|L A|32|G A|32|V TAF4 TATA binding protein-Associated Factor 388.0 0 0 0 0 0.36571203960223697 P50105 0.9432820081710817 0.9430609941482544 0.9484469890594482 0.9504740238189696 47.43704442824361 40.0 1.0 no 10175 chrXIII_276221 27198 essential YMR005W 176 + ATCTTCAACTCACAATGATG S|60|C S|60|F S|61|* S|61|L TAF4 TATA binding protein-Associated Factor 388.0 0 0 0 0 0.2472828723224731 P50105 0.945252001285553 0.9294660091400146 0.9298099875450134 0.05291058868169785 0.049659766256809235 0.24625299870967865 39.15428750967396 35.0 1.0 no 10176 chrXIII_276494 27202 essential YMR005W 449 + CGCAGGTATCGATGTTAGGG A|151|G A|151|V TAF4 TATA binding protein-Associated Factor 388.0 0 0 0 0 -1.051057896456815 P50105 0.9484469890594482 0.9504740238189696 0.0 0.0 50.30192167097539 55.00000000000001 1.0 no 10177 chrXIII_276590 27204 essential YMR005W 545 + CCATTTACCATTCCTTCACC H|183|D H|183|Y TAF4 TATA binding protein-Associated Factor 388.0 0 0 0 0 0.9354235404421574 P50105 0.9473130106925964 0.9489949941635132 0.6347779631614685 0.3871075510978699 53.40099061654961 45.0 1.0 no 10178 chrXIII_276597r 27206 essential YMR005W 555 - ACTTGTTCCGGGTGAAGGAA V|192|L V|192|I TAF4 TATA binding protein-Associated Factor 388.0 0 0 0 0 -1.58012974206434 P50105 0.9539830088615416 0.9574310183525084 0.7609953284263611 0.2934483289718628 -2.466320037841797 -1.2891000509262085 49.55630640187047 50.0 1.0 no 10179 chrXIII_276613 27207 essential YMR005W 568 + AACAAGTTTCCAATTATATG Q|191|E Q|191|* TAF4 TATA binding protein-Associated Factor 388.0 0 0 0 0 0.3034710438250557 P50105 0.9590039849281312 0.05232183262705803 35.300383707962396 25.0 1.0 no 10180 chrXIII_276622r 27209 essential YMR005W 580 - TCCGACTTTCCTCATATAAT G|200|R G|200|R G|200|A G|200|E TAF4 TATA binding protein-Associated Factor 388.0 0 0 0 0 -0.2496793493770396 P50105 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.062371168285608285 0.062371168285608285 1.0 0.08488380908966063 8.087800025939941 8.087800025939941 -0.010180000215768814 3.6620600223541264 45.54301325347103 35.0 1.0 no 10181 chrXIII_276671 27210 essential YMR005W 626 + TACAAAGAATCCTGAAATTT T|210|R T|210|I TAF4 TATA binding protein-Associated Factor 388.0 0 1 0 0 0.04777290658079325 P50105 0.9476869702339172 0.9472420215606691 0.3419367074966431 0.3872313499450684 -1.363960027694702 -0.4675399959087372 33.727649073021155 25.0 1.0 no 10182 chrXIII_276709r 27211 essential YMR005W 667 - ATCTCTCATATAGTTTTCGC D|229|H D|229|N R|228|T R|228|K TAF4 TATA binding protein-Associated Factor 388.0 0 0 0 0 1.0073813265392295 P50105 0.9486550092697144 0.956179976463318 0.932735025882721 0.955805003643036 0.3275993764400482 1.0 0.2163834124803543 0.4926522970199585 2.326859951019287 0.675320029258728 45.29922187485971 35.0 1.0 no 10183 chrXIII_276757r 27212 essential YMR005W 715 - GACTGCTTTTCTTCTATGTC V|245|L V|245|I A|244|P A|244|T TAF4 TATA binding protein-Associated Factor 388.0 0 0 0 0 -0.3586450475567765 P50105 0.9539830088615416 0.9574310183525084 0.9573720097541808 0.9523990154266356 0.20962588489055636 1.0 0.26485344767570496 0.06469690054655075 48.126574131519135 40.0 1.0 no 10184 chrXIII_295609r 27217 essential YMR013C 1107 + TTTCAAAACCTACCGCCGTT Q|371|E Q|371|* SEC59 SECretory 519.0 0 0 0 0 -0.6862909142406934 P20048 0.9590039849281312 0.020248819142580032 49.334659520837924 45.0 0.0 no 10185 chrXIII_295778r 27219 essential YMR013C 938 + ACCAAGTATATTGATCGAGA P|314|R P|314|L P|314|A P|314|S SEC59 SECretory 519.0 0 0 0 0 -0.5691045479012189 P20048 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 41.05694104551918 35.0 0.0 no 10186 chrXIII_295782 27220 essential YMR013C 937 - CTCGATCAATATACTTGGTA E|319|Q E|319|K L|317|F silent|TTG>TTA|L|317 SEC59 SECretory 519.0 0 0 0 0 0.2824400380945105 P20048 0.956179976463318 0.9475290179252625 0.9587849974632264 0.2865709066390991 0.28400737047195435 0.4293572902679443 41.06645432384346 35.0 0.0 no 10187 chrXIII_295878r 27221 essential YMR013C 838 + ACGGTGAAAATCCGCTACTT D|280|E silent|GAC>GAT|D|280 SEC59 SECretory 519.0 0 0 0 0 0.3813974825248593 P20048 0.9532920122146606 0.8967849612236023 45.809887113452426 45.0 0.0 no 10188 chrXIII_295938r 27224 essential YMR013C 778 + TGTCAATATCCTTTGCCATC S|261|* S|261|L SEC59 SECretory 519.0 0 0 0 0 -0.23439701431755944 P20048 0.9298099875450134 0.7193675041198729 48.96526351284696 40.0 0.0 no 10189 chrXIII_296038r 27225 essential YMR013C 678 + GTACATTTTAGAATTTTGAA H|228|D H|228|Y SEC59 SECretory 519.0 0 0 0 0 -0.2919204324790448 P20048 0.9473130106925964 0.9489949941635132 0.4065508246421814 1.0 33.490500827664675 20.0 0.0 no 10190 chrXIII_296065r 27226 essential YMR013C 651 + ATTCTGTACGTTTCAGAGGC L|219|V silent|CTG>TTG|L|219 SEC59 SECretory 519.0 0 0 0 0 0.09464175694751514 P20048 0.9512209892272948 0.199514701962471 48.945000962834165 45.0 0.0 no 10191 chrXIII_296341 27228 essential YMR013C 378 - AACAACAACGAAACCATAAA L|132|F silent|TTG>TTA|L|132 L|131|F silent|TTG>TTA|L|131 SEC59 SECretory 519.0 0 0 0 0 1.0327187559235933 P20048 0.9587849974632264 0.9587849974632264 0.04492434114217758 0.4362732768058777 32.944550003924014 30.0 0.0 no 10192 chrXIII_296418r 27230 essential YMR013C 298 + GTCTGATATTCACAAAATAT L|101|V silent|CTG>TTG|L|101 SEC59 SECretory 519.0 0 0 0 0 0.3479615156826647 P20048 0.9512209892272948 1.0 34.686283606274465 25.0 0.0 no 10193 chrXIII_296497 27231 essential YMR013C 222 - TCAGCGGTAACAATGGACCA D|81|H D|81|N A|80|P A|80|T SEC59 SECretory 519.0 0 0 0 0 0.002875070488801645 P20048 0.9486550092697144 0.956179976463318 0.9573720097541808 0.9523990154266356 0.1341361552476883 0.3997834324836731 0.2414183020591736 0.4637760818004608 48.46541130339125 50.0 0.0 no 10194 chrXIII_296685 27234 essential YMR013C 34 - TTTCTGGGTTAGTTTAATTG Q|17|H silent|CAG>CAA|Q|17 SEC59 SECretory 519.0 0 1 0 0 0.3926325941265458 P20048 0.9570760130882264 40.625648807867776 30.0 0.0 no 10195 chrXIII_327619 27237 essential YMR028W 137 + AACAGCAATTTTTGACAGGT T|47|R T|47|I A|48|G A|48|V TAP42 Two A phosphatase Associated Protein 366.0 0 0 0 0 0.6735078267135521 Q04372 0.9476869702339172 0.9472420215606691 0.9484469890594482 0.9504740238189696 0.2500219941139221 0.09765644371509552 0.5160875916481018 0.4758563339710236 0.318340003490448 -0.22485999763011927 1.4132399559020996 0.2698200047016144 1.423840045928955 -1.0059599876403809 41.98217301108372 35.0 1.0 no 10196 chrXIII_327845 27239 essential YMR028W 363 + AAGCTTCTAGATCCTTTGGT L|123|V L|123|F L|124|V silent|CTA>TTA|L|124 TAP42 Two A phosphatase Associated Protein 366.0 0 0 0 0 0.05013755200974071 Q04372 0.9512209892272948 0.9587849974632264 0.9512209892272948 0.44481104612350464 0.04026585817337036 0.0 2.0704801082611084 2.1959800720214844 2.1489000320434566 2.60971999168396 0.574999988079071 3.004460096359253 49.36039329722496 40.0 1.0 no 10197 chrXIII_327857r 27240 essential YMR028W 378 - CCTAGTTTTTCACCAACCAA G|133|R G|133|S TAP42 Two A phosphatase Associated Protein 366.0 0 0 0 0 0.4691399482523937 Q04372 0.941340982913971 0.951104998588562 0.3439900875091553 0.3217584192752838 -1.2213599681854248 0.013539999723434448 48.21600401504811 40.0 1.0 no 10198 chrXIII_327991r 27241 essential YMR028W 512 - TGCTAATTTCTTTATTGCGC S|177|T S|177|N TAP42 Two A phosphatase Associated Protein 366.0 0 0 0 0 -0.3466906238828425 Q04372 0.9512869715690612 0.9536849856376648 0.42277345061302185 0.7104722261428833 0.2868199944496155 -0.4860399961471558 0.4397999942302704 -0.7512000203132629 44.691696222036676 35.0 1.0 no 10199 chrXIII_328066r 27243 essential YMR028W 587 - GTTCTCTTAGTAATTCATCA E|202|Q E|202|K R|201|T R|201|K TAP42 Two A phosphatase Associated Protein 366.0 0 0 0 0 0.2284923876691197 Q04372 0.956179976463318 0.9475290179252625 0.932735025882721 0.955805003643036 0.610396683216095 0.85124671459198 0.0 0.0 -0.3996999859809876 -0.25797998905181885 2.678999900817871 1.7422599792480469 42.47587536996792 30.0 1.0 no 10200 chrXIII_328009 27244 essential YMR028W 527 + TAGCACAAAACTGCACTGCT S|177|R silent|AGC>AGT|S|177 T|178|R T|178|I TAP42 Two A phosphatase Associated Protein 366.0 0 0 0 0 0.5320049779025983 Q04372 0.9417110085487366 0.9476869702339172 0.9472420215606691 0.4017013311386109 0.5007182359695435 0.1811894029378891 -0.44064000248909 -0.492220014333725 -0.7196199893951416 0.4350000023841858 45.78225044852201 45.0 1.0 no 10201 chrXIII_328177r 27245 essential YMR028W 698 - CTTCATGTACGGAATTTTTG E|239|Q E|239|K TAP42 Two A phosphatase Associated Protein 366.0 0 0 0 0 0.7469606882867318 Q04372 0.956179976463318 0.9475290179252625 0.5401704311370851 0.8654279112815857 40.47138633530068 35.0 1.0 no 10202 chrXIII_328283 27246 essential YMR028W 801 + AAGCCATTGATAGACAAAAA P|269|A P|269|S P|269|R P|269|L TAP42 Two A phosphatase Associated Protein 366.0 0 0 0 0 -0.6823854399545662 Q04372 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.4750750660896301 0.468472957611084 0.09616579115390778 0.31040051579475403 35.58400505671733 30.0 1.0 no 10203 chrXIII_337957 27249 essential YMR033W 83 + AACATTCACTGTACCTGAGC T|29|R T|29|I F|30|L silent|TTC>TTT|F|30 ARP9 Actin-Related Protein 467.0 0 0 0 0 0.32058542858116706 Q05123 0.0869225561618805 0.08611489087343216 0.7446673512458801 0.030319999903440475 -0.7271999716758728 1.498280048370361 0.5892000198364258 47.298879585046336 45.0 1.0 no 10204 chrXIII_337997 27250 essential YMR033W 123 + TATCGGACCACGAGACAAGA R|43|G R|43|W ARP9 Actin-Related Protein 467.0 0 0 0 0 -2.570119899227421 Q05123 0.1453496813774109 0.013629445806145668 2.1256799697875977 5.273719787597656 45.654272750676746 50.0 1.0 yes 10205 chrXIII_338077r 27252 essential YMR033W 206 - TGTCTATTATTTCACCATTT D|75|H D|75|N ARP9 Actin-Related Protein 467.0 0 0 0 0 0.5126814508130239 Q05123 0.022530602291226387 0.4752672612667084 5.262519836425781 4.284599781036377 42.5501369381401 25.0 1.0 no 10206 chrXIII_338221r 27254 essential YMR033W 350 - GATCCGATTGCGACCAAGAG D|123|H D|123|N silent|TCG>TCC|S|122 silent|TCG>TCA|S|122 ARP9 Actin-Related Protein 467.0 0 0 0 0 -0.9057026462222292 Q05123 0.2698972225189209 0.8835718035697937 0.21437999606132507 0.7375800013542175 48.98663248540443 55.00000000000001 1.0 no 10207 chrXIII_338284 27255 essential YMR033W 410 + AAACAATCTAATCCAATTGC N|138|K silent|AAC>AAT|N|138 ARP9 Actin-Related Protein 467.0 0 0 0 0 0.6729435745307538 Q05123 0.4479338228702545 -0.6858999729156494 36.53172203460076 30.0 1.0 no 10208 chrXIII_338208 27256 essential YMR033W 334 + TACTGATTACGCACCACTCT L|113|V silent|CTG>TTG|L|113 ARP9 Actin-Related Protein 467.0 0 0 0 0 0.04374678679031538 Q05123 0.05323191359639168 1.9931600093841555 49.01650166204047 45.0 1.0 no 10209 chrXIII_338480r 27258 essential YMR033W 609 - ATCTGATCATCGTCCCATTG Q|209|H silent|CAG>CAA|Q|209 ARP9 Actin-Related Protein 467.0 0 0 0 0 -3.1001853525905765 Q05123 0.01394997350871563 0.4568000137805938 50.46277611900348 45.0 1.0 yes 10210 chrXIII_338555 27259 essential YMR033W 681 + AAACTATCAAGTTTCGATTT L|229|V silent|CTA>TTA|L|229 ARP9 Actin-Related Protein 467.0 0 0 0 0 -0.3092925392768692 Q05123 0.6555250287055969 0.2034000009298325 36.08876708100661 25.0 1.0 no 10211 chrXIII_338522r 27260 essential YMR033W 651 - TCACTGAGCACCTCAAAAAT S|223|T S|223|N D|224|H D|224|N ARP9 Actin-Related Protein 467.0 0 0 0 0 -0.2280099825263267 Q05123 0.3598848879337311 0.4647994041442871 0.011848188936710358 0.026388388127088547 -0.22324000298976895 0.06666000187397003 0.6636000275611877 -1.2610000371932983 42.50297315385506 40.0 1.0 no 10212 chrXIII_338619r 27261 essential YMR033W 748 - ACGACCACTTGTAATAATCT R|256|P R|256|H G|255|A G|255|D ARP9 Actin-Related Protein 467.0 0 0 0 0 -1.2085761534786177 Q05123 0.012367998249828815 0.013739286921918392 0.1256249099969864 0.6322384476661682 3.2537999153137207 0.03759999945759773 41.61104280321479 35.0 1.0 no 10213 chrXIII_338706 27262 essential YMR033W 832 + ACTTGGAATTCAATACTTTT D|278|E silent|GAC>GAT|D|278 ARP9 Actin-Related Protein 467.0 0 0 0 0 0.5704778900031805 Q05123 1.0 0.11819999665021895 37.49124644336115 25.0 1.0 no 10214 chrXIII_338842 27263 essential YMR033W 968 + TAACAAAGCTAAAGCCGTTT N|324|K silent|AAC>AAT|N|324 ARP9 Actin-Related Protein 467.0 0 0 0 0 0.3358160007906932 Q05123 0.9450248479843141 0.2788800001144409 40.178442732395524 35.0 1.0 no 10215 chrXIII_353895r 27264 essential YMR043W 27 - TTCTGTTGCCCATTATTAGT Q|15|H silent|CAG>CAA|Q|15 0 0 0 0 -0.4093991253034368 P11746 0.8437860012054443 0.061262886971235275 0.2442999929189682 0.03923999890685082 49.952331664725186 35.0 1.0 no 10216 chrXIII_354105r 27272 essential YMR043W 237 - CCTTCCTGCTGCGTGACTAT G|86|R G|86|S E|85|Q E|85|K 0 0 0 0 -2.41291867595253 P11746 0.7779420018196106 0.8973569869995117 0.9388740062713624 0.9074789881706238 0.0 0.0 0.0 0.0 5.830860137939452 5.533100128173828 -0.09703999757766724 0.2428800016641617 10.625054359436037 5.521038055419922 0.32434800267219543 0.3743320107460022 57.347310697369146 55.00000000000001 1.0 yes 10217 chrXIII_354158r 27275 essential YMR043W 290 - CGTCTTCTTCCTCATCATCA D|103|H D|103|N E|102|Q E|102|K 0 0 0 0 0.10253555188103636 P11746 0.9899479746818542 1.0004899501800537 1.0004899501800537 0.9891330003738404 0.15124738216400144 0.9647445678710938 0.444432944059372 0.5752565264701843 53.10567528390243 45.0 1.0 no 10218 chrXIII_354044r 27276 essential YMR043W 176 - TTTCTGAAACGACTAGCAAC E|65|Q E|65|K 0 0 0 0 0.2327753829940038 P11746 0.9506070017814636 0.9382569789886476 0.05131933093070984 0.0048356237821280965 0.7025200128555298 1.0682799816131592 0.2226809859275818 0.5475369691848755 39.63313592553278 40.0 1.0 no 10219 chrXIII_354305 27277 essential YMR043W 434 + AGGCCATCTAAATCAAGATC silent|GGC>GGG|G|146 silent|GGC>GGT|G|146 H|147|D H|147|Y 0 0 0 0 0.22189218647326134 P11746 0.9917020201683044 0.9918540120124816 0.5934911966323853 0.107939213514328 42.758005050762506 40.0 1.0 no 10220 chrXIII_354157r 27278 essential YMR043W 289 - GTCTTCTTCCTCATCATCAG D|103|H D|103|N E|102|Q E|102|K 0 0 0 0 0.8725937767707795 P11746 0.9899479746818542 1.0004899501800537 1.0004899501800537 0.9891330003738404 0.15124738216400144 0.9647445678710938 0.444432944059372 0.5752565264701843 52.310020419977654 45.0 1.0 no 10221 chrXIII_354308r 27279 essential YMR043W 440 - GTACCTGATCTTGATTTAGA V|153|L V|153|I Q|152|H silent|CAG>CAA|Q|152 0 0 0 0 0.4514254451243416 P11746 0.9940739870071412 1.0010499954223633 1.0006899833679201 0.5697049498558044 0.34581491351127625 0.24195632338523865 43.985137560586175 35.0 1.0 no 10222 chrXIII_354311 27280 essential YMR043W 440 + TCTAAATCAAGATCAGGTAC L|148|V silent|CTA>TTA|L|148 0 1 0 0 -0.3847416603766972 P11746 0.9950990080833436 0.5264679789543152 37.58830747640866 35.0 1.0 no 10223 chrXIII_354330r 27283 essential YMR043W 462 - TCTTGTTTCAGCGCGCCTGC E|161|Q E|161|K 0 0 0 0 1.0973036033338783 P11746 1.0004899501800537 0.9891330003738404 0.566528856754303 0.8616698980331421 60.442838327839404 60.0 1.0 no 10224 chrXIII_354495 27284 essential YMR043W 624 + CAGCATCCTCGACCACAGCA H|210|D H|210|Y P|211|A P|211|S 0 0 0 0 -0.5968657904593213 P11746 0.9917020201683044 0.9918540120124816 1.0004199743270874 0.9926369786262512 0.05112933740019798 0.2620798945426941 0.03734937310218811 0.1031806468963623 57.52889564520718 60.0 1.0 no 10225 chrXIII_364247 27286 essential YMR047C 2439 - TCAATGGAAATCGACAACTT D|820|H D|820|N NUP116 NUclear Pore 1113.0 0 1 0 0 -0.2538105449091923 Q02630 0.1280844658613205 0.5069548487663269 37.56801414287133 35.0 0.0 no 10226 chrXIII_364469r 27291 essential YMR047C 2214 + ATTCAGAATAACAATCCCTA Q|740|E Q|740|* NUP116 NUclear Pore 1113.0 0 0 0 0 0.4442410257469954 Q02630 1.0 39.954562622483024 30.0 0.0 no 10227 chrXIII_364577r 27295 essential YMR047C 2106 + AACACTAGTACGAACACTTC N|703|K silent|AAC>AAT|N|703 T|704|S T|704|I NUP116 NUclear Pore 1113.0 0 0 0 0 0.09644188260924444 Q02630 1.0 0.7030543088912964 0.1780848354101181 40.03197685930121 40.0 0.0 no 10228 chrXIII_364578r 27296 essential YMR047C 2105 + TAACACTAGTACGAACACTT N|703|K silent|AAC>AAT|N|703 T|704|S T|704|I NUP116 NUclear Pore 1113.0 0 0 0 0 -0.3955905250181898 Q02630 1.0 0.7030543088912964 0.1780848354101181 38.66329055134844 35.0 0.0 no 10229 chrXIII_364613r 27298 essential YMR047C 2070 + TCTCAATCTACTAATGCTGG Q|692|E Q|692|* S|691|C S|691|F NUP116 NUclear Pore 1113.0 0 0 0 0 -0.4258919936509981 Q02630 0.3795135915279389 0.09736931324005127 0.07394976168870926 43.08470159188312 40.0 0.0 no 10230 chrXIII_364616r 27299 essential YMR047C 2067 + ACCTCTCAATCTACTAATGC silent|ACC>ACG|T|690 silent|ACC>ACT|T|690 T|690|S T|690|I NUP116 NUclear Pore 1113.0 0 0 0 0 -1.1832637484052828 Q02630 0.9990484118461608 0.2044688314199448 44.993195989770406 40.0 0.0 no 10231 chrXIII_364651 27300 essential YMR047C 2035 - AAACAGGCCCGTTGAACCGT silent|CTG>CTC|L|684 silent|CTG>CTA|L|684 NUP116 NUclear Pore 1113.0 0 0 0 0 0.12214007297140098 Q02630 52.29019302938968 55.00000000000001 0.0 no 10232 chrXIII_364658r 27302 essential YMR047C 2025 + AACAATTCCAACGGTTCAAC N|676|K silent|AAC>AAT|N|676 NUP116 NUclear Pore 1113.0 0 0 0 0 0.6739891593495803 Q02630 0.2797246277332306 41.269464076761096 40.0 0.0 no 10233 chrXIII_364659r 27303 essential YMR047C 2024 + AAACAATTCCAACGGTTCAA N|676|K silent|AAC>AAT|N|676 NUP116 NUclear Pore 1113.0 0 0 0 0 0.3063899078954139 Q02630 0.2797246277332306 39.62736899311057 35.0 0.0 no 10234 chrXIII_364754r 27307 essential YMR047C 1929 + ACCAATTCTACTGGTTTATT silent|ACC>ACG|T|644 silent|ACC>ACT|T|644 T|644|S T|644|I NUP116 NUclear Pore 1113.0 0 0 0 0 0.5501725518668217 Q02630 1.0 0.04782877117395401 43.20999151989059 30.0 0.0 no 10235 chrXIII_364763r 27308 essential YMR047C 1920 + GCGGCCACCACCAATTCTAC A|641|G A|641|V A|642|G A|642|V NUP116 NUclear Pore 1113.0 0 0 0 0 0.14215683385192102 Q02630 0.6224371194839478 0.2761343419551849 0.6285676956176758 0.20476824045181274 56.868894473514274 60.0 0.0 no 10236 chrXIII_364807 27309 essential YMR047C 1879 - CCCAAATATTCCACCCGAAG G|633|R G|633|R G|633|A G|633|E NUP116 NUclear Pore 1113.0 0 0 0 0 -1.4292590223605208 Q02630 0.0 0.0 0.0 0.0 49.25730801007865 50.0 0.0 no 10237 chrXIII_364839r 27314 essential YMR047C 1844 + TTTCGGAGGTACTAATTCCA F|616|L silent|TTC>TTT|F|616 NUP116 NUclear Pore 1113.0 0 0 0 0 0.7311026349248315 Q02630 1.0 46.567051835196885 40.0 0.0 no 10238 chrXIII_364886r 27318 essential YMR047C 1797 + TCAACTAGCGGCGGATTATT S|600|* S|600|L T|601|S T|601|I NUP116 NUclear Pore 1113.0 0 0 0 0 0.02349245149163784 Q02630 0.2834775745868683 1.0 0.26014479994773865 47.33629948869219 45.0 0.0 no 10239 chrXIII_364898r 27320 essential YMR047C 1785 + AACAATCCTGCCTCAACTAG N|596|K silent|AAC>AAT|N|596 P|598|A P|598|S NUP116 NUclear Pore 1113.0 0 0 0 0 0.4834004111535846 Q02630 0.9252014756202698 0.8685411810874939 0.8154805898666382 46.3301646520451 45.0 0.0 no 10240 chrXIII_364958r 27323 essential YMR047C 1725 + TCAAAACCATCAAACACTGT S|576|* S|576|L P|578|A P|578|S NUP116 NUclear Pore 1113.0 0 0 0 0 -0.2719241499284836 Q02630 0.5667844414710999 0.5957462191581726 0.7298589944839478 38.983092110742405 35.0 0.0 no 10241 chrXIII_364991r 27326 essential YMR047C 1692 + AAACAGCAACCTGCTTCGGG Q|566|E Q|566|* Q|567|E Q|567|* NUP116 NUclear Pore 1113.0 0 0 0 0 -0.8435030211818946 Q02630 0.4488519728183745 0.5665575265884399 49.78636743880958 55.00000000000001 0.0 no 10242 chrXIII_365063r 27329 essential YMR047C 1620 + AGCACAACAAATCAAAGTAA S|541|R silent|AGC>AGT|S|541 T|542|R T|542|I NUP116 NUclear Pore 1113.0 0 0 0 0 0.5864562923365466 Q02630 0.1607973426580429 0.4686884582042694 0.20605993270874026 34.13176464358099 30.0 0.0 no 10243 chrXIII_365129r 27330 essential YMR047C 1554 + CAACAGAATAATAGTCTTTT Q|520|E Q|520|* NUP116 NUclear Pore 1113.0 0 0 0 0 0.6196471858911172 Q02630 0.762663722038269 34.288118347993304 25.0 0.0 no 10244 chrXIII_365206 27333 essential YMR047C 1480 - GCCAAACAATCCACCAGGTT G|500|R G|500|S G|500|A G|500|D NUP116 NUclear Pore 1113.0 0 0 0 0 -0.022606817301498026 Q02630 0.2538679242134094 0.5570186376571655 0.4417867064476013 0.7062543630599976 51.581164812390966 50.0 0.0 no 10245 chrXIII_365201 27334 essential YMR047C 1485 - GTCTGGCCAAACAATCCACC Q|501|H silent|CAG>CAA|Q|501 G|500|A G|500|D NUP116 NUclear Pore 1113.0 0 0 0 0 0.4846456468609667 Q02630 0.2560425102710724 0.4417867064476013 0.7062543630599976 52.751496518458225 55.00000000000001 0.0 no 10246 chrXIII_365262r 27335 essential YMR047C 1421 + CCAACAACAGCAATCAACCG Q|475|E Q|475|* Q|476|E Q|476|* NUP116 NUclear Pore 1113.0 0 0 0 0 -0.008650733648195684 Q02630 0.8902067542076111 1.0 44.64200841569499 50.0 0.0 no 10247 chrXIII_365261r 27336 essential YMR047C 1422 + CAACAACAGCAATCAACCGG Q|476|E Q|476|* Q|477|E Q|477|* NUP116 NUclear Pore 1113.0 0 0 0 0 0.3844350043547407 Q02630 1.0 0.9200371503829956 43.395477880088826 50.0 0.0 no 10248 chrXIII_365263r 27337 essential YMR047C 1420 + ACCAACAACAGCAATCAACC Q|475|E Q|475|* N|474|K silent|AAC>AAT|N|474 NUP116 NUclear Pore 1113.0 0 0 0 0 -1.890265147950684 Q02630 0.8902067542076111 0.3133397400379181 43.95038440528475 45.0 0.0 no 10249 chrXIII_365351 27340 essential YMR047C 1335 - TGTCCAAACAGTCCTCCTGC G|451|A G|451|E G|451|R G|451|R NUP116 NUclear Pore 1113.0 0 0 0 0 0.7085971222509042 Q02630 1.0 0.3052268624305725 0.2812991142272949 0.2812991142272949 56.120065766042224 55.00000000000001 0.0 no 10250 chrXIII_365354r 27341 essential YMR047C 1329 + AAACCTGCAGGAGGACTGTT P|445|A P|445|S P|445|R P|445|L NUP116 NUclear Pore 1113.0 0 0 0 0 -0.4862370602140407 Q02630 0.5849950909614563 0.7371601462364197 0.5295315384864807 0.2437199801206589 49.52711636626884 50.0 0.0 no 10251 chrXIII_365486r 27344 essential YMR047C 1197 + CAACAAAATTCCAACGCTGG Q|401|E Q|401|* NUP116 NUclear Pore 1113.0 0 0 0 0 0.7383963357765163 Q02630 0.4504358768463135 41.223804182290614 45.0 0.0 no 10252 chrXIII_365525r 27349 essential YMR047C 1158 + ACCAATCAGCAGCAAAGTGG silent|ACC>ACG|T|387 silent|ACC>ACT|T|387 T|387|S T|387|I NUP116 NUclear Pore 1113.0 0 0 0 0 -0.5830414549959643 Q02630 0.5105057954788208 0.09615492820739746 47.46651030281845 50.0 0.0 no 10253 chrXIII_365551r 27350 essential YMR047C 1132 + GTACCACTGGTGGCTTATTT T|379|S T|379|I silent|ACC>ACG|T|379 silent|ACC>ACT|T|379 NUP116 NUclear Pore 1113.0 0 0 0 0 -0.014034101441791402 Q02630 0.7850323915481567 0.2013933956623077 52.39014120634186 45.0 0.0 no 10254 chrXIII_365548 27351 essential YMR047C 1138 - TTGCCCAAATAAGCCACCAG silent|GGG>GGC|G|385 silent|GGG>GGA|G|385 G|385|A G|385|E NUP116 NUclear Pore 1113.0 0 0 0 0 0.2136076873329496 Q02630 0.9352927803993224 0.654589056968689 50.76154453206408 50.0 0.0 no 10255 chrXIII_365621r 27355 essential YMR047C 1062 + CCTGCTTCTGGTGGACTATT P|355|R P|355|L A|356|G A|356|V NUP116 NUclear Pore 1113.0 0 0 0 0 1.1457213718308514 Q02630 0.09493903070688248 0.05871623381972312 0.3050630986690521 0.2678632140159607 54.26063921586507 50.0 0.0 no 10256 chrXIII_365734 27360 essential YMR047C 952 - ACCTTGTTGTGTTTGTTGTT G|324|R G|324|S G|324|A G|324|D NUP116 NUclear Pore 1113.0 0 0 0 0 0.03507226591015256 Q02630 0.1586855798959732 0.5654410719871521 0.6991006135940552 0.20637688040733335 49.993675906933966 35.0 0.0 no 10257 chrXIII_365764 27361 essential YMR047C 922 - ACCACGATTCACCTGACCAA G|314|R G|314|S G|314|A G|314|D NUP116 NUclear Pore 1113.0 0 0 0 0 -0.09481766173231054 Q02630 0.11404845863580705 0.24030497670173645 0.15022726356983185 0.3633338809013367 50.94265248914309 50.0 0.0 no 10258 chrXIII_365812r 27368 essential YMR047C 871 + GTCAACAGCAAAATTCATTT Q|292|E Q|292|* Q|293|E Q|293|* NUP116 NUclear Pore 1113.0 0 0 0 0 -0.7806917016767523 Q02630 0.11508530378341675 0.2885790169239044 38.1005599589592 30.0 0.0 no 10259 chrXIII_365813r 27369 essential YMR047C 870 + GGTCAACAGCAAAATTCATT Q|292|E Q|292|* Q|293|E Q|293|* NUP116 NUclear Pore 1113.0 0 0 0 0 0.658058276480869 Q02630 0.11508530378341675 0.2885790169239044 40.15681052521694 35.0 0.0 no 10260 chrXIII_365846r 27370 essential YMR047C 837 + CAGCAGAACTCAAATACAAA Q|281|E Q|281|* NUP116 NUclear Pore 1113.0 0 0 0 0 0.8881152163956323 Q02630 0.2601934969425201 35.9189823227984 35.0 0.0 no 10261 chrXIII_365870r 27371 essential YMR047C 813 + ACTAATAATACAGGCCTTTT T|272|S T|272|I NUP116 NUclear Pore 1113.0 0 0 0 0 -0.4028476202404541 Q02630 0.8924569487571716 0.2148030698299408 41.21961131449996 30.0 0.0 no 10262 chrXIII_365879r 27372 essential YMR047C 804 + ACAAACGGCACTAATAATAC T|269|R T|269|I N|270|K silent|AAC>AAT|N|270 NUP116 NUclear Pore 1113.0 0 0 0 0 -1.2345199771772064 Q02630 0.5695640444755554 0.3548043370246887 0.5971153378486633 36.136553757385 35.0 0.0 no 10263 chrXIII_365894r 27373 essential YMR047C 789 + ACAACTAACAACCCAACAAA T|264|R T|264|I T|265|S T|265|I NUP116 NUclear Pore 1113.0 0 0 0 0 -0.6978372799705785 Q02630 0.4685533940792084 0.1772773116827011 0.5110384821891785 0.03688812255859375 37.886056521933476 35.0 0.0 no 10264 chrXIII_365920 27375 essential YMR047C 766 - ACCAAACAATCCCCCGGAAG G|262|R G|262|S G|262|A G|262|D NUP116 NUclear Pore 1113.0 0 0 0 0 -1.253904682631078 Q02630 0.6367146968841553 0.8424983024597168 0.8434677124023438 0.7655799388885498 50.50102157033081 55.00000000000001 0.0 no 10265 chrXIII_365933r 27377 essential YMR047C 750 + GCAAATAAACCTGCCACTTC A|251|G A|251|V NUP116 NUclear Pore 1113.0 0 0 0 0 0.2917275514465998 Q02630 0.16047441959381106 0.3977910876274109 45.84055952125033 45.0 0.0 no 10266 chrXIII_365957r 27378 essential YMR047C 726 + CTCTCAGGAAATTCTGCATT silent|CTC>CTG|L|243 silent|CTC>CTT|L|243 S|244|* S|244|L NUP116 NUclear Pore 1113.0 0 0 0 0 0.4204400564739501 Q02630 0.04224948212504387 45.04696365409506 40.0 0.0 no 10267 chrXIII_365992 27379 essential YMR047C 694 - TCCAAACAATCCTGTAGAGT G|238|R G|238|R G|238|A G|238|E NUP116 NUclear Pore 1113.0 0 0 0 0 -0.5279627963968596 Q02630 0.34239518642425537 0.34239518642425537 0.5778753757476807 0.4302934110164641 45.01159715511056 40.0 0.0 no 10268 chrXIII_365993r 27381 essential YMR047C 690 + ACCAACTCTACAGGATTGTT silent|ACC>ACG|T|231 silent|ACC>ACT|T|231 T|231|S T|231|I NUP116 NUclear Pore 1113.0 0 0 0 0 -0.26873048010613915 Q02630 0.9128959774971008 0.2969754040241241 46.29424348806919 40.0 0.0 no 10269 chrXIII_366031 27384 essential YMR047C 655 - GCCACCACCACTTCCAGTTC G|225|R G|225|S G|225|A G|225|D NUP116 NUclear Pore 1113.0 0 0 0 0 -0.8275526474922411 Q02630 0.28535249829292303 0.7081105709075928 1.0 0.378487229347229 61.68236190966225 60.0 0.0 no 10270 chrXIII_366053 27386 essential YMR047C 633 - GTTCCAAACATGCCTGTTGC G|217|A G|217|E G|217|R G|217|R NUP116 NUclear Pore 1113.0 0 0 0 0 0.5489362551682896 Q02630 0.084837906062603 0.08274668455123901 0.04528272524476051 0.04528272524476051 52.45540860541888 50.0 0.0 no 10271 chrXIII_366056r 27388 essential YMR047C 627 + AAGCCAGCAACAGGCATGTT P|211|A P|211|S P|211|R P|211|L NUP116 NUclear Pore 1113.0 0 0 0 0 -0.6696618884671556 Q02630 0.3197644352912903 0.7622179985046387 0.0919928327202797 0.08672326803207397 51.89045346486535 50.0 0.0 no 10272 chrXIII_366083r 27389 essential YMR047C 600 + GCTACAACAGGAGGATTATT A|201|G A|201|V T|202|R T|202|I NUP116 NUclear Pore 1113.0 0 0 0 0 -0.3960191438272113 Q02630 0.9610652327537536 0.10253442078828813 0.29287296533584595 0.1620875746011734 43.43495403755429 40.0 0.0 no 10273 chrXIII_366092r 27390 essential YMR047C 591 + ACTACTTCTGCTACAACAGG T|198|S T|198|I T|199|S T|199|I NUP116 NUclear Pore 1113.0 0 0 0 0 0.9410679824456222 Q02630 0.9439773559570312 0.18857887387275696 0.9886409640312196 0.3470720648765564 45.653009590046565 45.0 0.0 no 10274 chrXIII_366095r 27392 essential YMR047C 588 + TCCACTACTTCTGCTACAAC silent|TCC>TCG|S|197 silent|TCC>TCT|S|197 S|197|C S|197|F NUP116 NUclear Pore 1113.0 0 0 0 0 -0.15026798062383334 Q02630 0.0664929449558258 0.07203925400972366 48.03515089670276 45.0 0.0 no 10275 chrXIII_366158r 27393 essential YMR047C 525 + ACTACTTTTAACAATCCTCA T|176|S T|176|I T|177|S T|177|I NUP116 NUclear Pore 1113.0 0 0 0 0 0.18751840912531045 Q02630 0.8241937160491943 0.2073601484298706 0.8630886673927307 0.1097879484295845 41.17130037002357 30.0 0.0 no 10276 chrXIII_366320 27395 essential YMR047C 366 - TTCTCTTCGAATGTAGTAAA E|128|D silent|GAG>GAA|E|128 E|128|Q E|128|K NUP116 NUclear Pore 1113.0 0 0 0 0 -0.014212252222595869 Q02630 0.0 0.0 0.0 38.24895913645503 30.0 0.0 no 10277 chrXIII_366418 27397 essential YMR047C 268 - TCCACCGAAGATCGAGCCAG G|96|R G|96|R G|96|A G|96|E NUP116 NUclear Pore 1113.0 0 0 0 0 -0.6514173776426768 Q02630 0.3681880533695221 0.3681880533695221 1.0 0.5094268918037415 53.29430393805114 60.0 0.0 no 10278 chrXIII_366452 27401 essential YMR047C 234 - GTCAATTGACTTTGACCAAA L|84|F silent|TTG>TTA|L|84 NUP116 NUclear Pore 1113.0 0 0 0 0 0.6020906904585832 Q02630 0.1308521032333374 40.76193904077167 35.0 0.0 no 10279 chrXIII_366530 27403 essential YMR047C 156 - TTACCAAAGTTACCAAACGC G|58|A G|58|D G|58|R G|58|S NUP116 NUclear Pore 1113.0 0 0 0 0 0.18234848693380884 Q02630 1.0 0.7884796261787415 0.5237355828285217 0.8147861361503601 42.0272635518528 40.0 0.0 no 10280 chrXIII_366533r 27404 essential YMR047C 150 + GCACCTGCGTTTGGTAACTT P|52|A P|52|S A|51|G A|51|V NUP116 NUclear Pore 1113.0 0 0 0 0 -0.3020874239864593 Q02630 1.0 0.6682043075561523 1.0 0.036798849701881416 53.424939300542746 50.0 0.0 no 10281 chrXIII_366632r 27406 essential YMR047C 51 + GGCTCAACAGGATCAACCTT silent|GGC>GGG|G|18 silent|GGC>GGT|G|18 S|19|* S|19|L NUP116 NUclear Pore 1113.0 0 0 0 0 -0.953221229697972 Q02630 0.109041266143322 50.30863575713904 50.0 0.0 no 10282 chrXIII_368712r 27409 essential YMR049C 1783 + AAACAGTAAAAAAGCTTTCA T|596|R T|596|I ERB1 Eukaryotic Ribosome Biogenesis 807.0 0 0 0 0 -0.9173420490914476 Q04660 0.9476869702339172 0.9472420215606691 0.02095624804496765 0.1899227797985077 -0.3952600061893463 -0.5941799879074097 32.13849274061722 25.0 0.0 no 10283 chrXIII_368914r 27410 essential YMR049C 1581 + ACTAAGATTGAAGATGGTTT T|528|S T|528|I ERB1 Eukaryotic Ribosome Biogenesis 807.0 0 0 0 0 0.2318707339450643 Q04660 0.9491789937019348 0.9472420215606691 0.7144744992256165 0.19159366190433505 -0.10660000145435332 -0.5004600286483765 37.36730735996025 30.0 0.0 no 10284 chrXIII_369047 27412 essential YMR049C 1451 - TGCATTCAATGTGGTAATCT C|490|S C|490|Y E|489|Q E|489|K ERB1 Eukaryotic Ribosome Biogenesis 807.0 0 0 0 0 -1.628644559858201 Q04660 0.9421560168266296 0.9290120005607604 0.956179976463318 0.9475290179252625 1.0 0.9222153425216676 0.3137282133102417 0.312010258436203 0.4277200102806091 1.1444400548934937 -0.8057199716567993 -1.0353800058364868 43.350744486974286 35.0 0.0 no 10285 chrXIII_369046 27413 essential YMR049C 1452 - ATGCATTCAATGTGGTAATC C|490|S C|490|Y ERB1 Eukaryotic Ribosome Biogenesis 807.0 0 0 0 0 -0.06032238872048419 Q04660 0.9421560168266296 0.9290120005607604 1.0 0.9222153425216676 0.4277200102806091 1.1444400548934937 41.50310405655063 35.0 0.0 no 10286 chrXIII_369131r 27416 essential YMR049C 1364 + ATCTGATGACGGAACAGTCA S|456|C S|456|F ERB1 Eukaryotic Ribosome Biogenesis 807.0 0 0 0 0 -0.9212339369129104 Q04660 0.945252001285553 0.9294660091400146 0.026677392423152924 0.011297918856143951 2.393199920654297 29.718351364135746 44.82748346749224 45.0 0.0 no 10287 chrXIII_369165r 27418 essential YMR049C 1330 + CCATTGATCCTTCTGGATTA silent|TCC>TCG|S|444 silent|TCC>TCT|S|444 ERB1 Eukaryotic Ribosome Biogenesis 807.0 0 0 0 0 0.20689916245158824 Q04660 48.8509772019948 40.0 0.0 no 10288 chrXIII_369172r 27419 essential YMR049C 1323 + ACATTATCCATTGATCCTTC T|442|R T|442|I ERB1 Eukaryotic Ribosome Biogenesis 807.0 0 0 0 0 -0.11343918391229248 Q04660 0.9476869702339172 0.9472420215606691 0.037320613861083984 0.04363369569182396 2.0361199378967285 1.319599986076355 46.199929632152426 35.0 0.0 no 10289 chrXIII_369074r 27423 essential YMR049C 1421 + AACTACTTTAATCGATGACG T|475|S T|475|I T|476|S T|476|I ERB1 Eukaryotic Ribosome Biogenesis 807.0 0 0 0 0 0.5537769082180388 Q04660 0.9491789937019348 0.9472420215606691 0.9491789937019348 0.9472420215606691 0.35483530163764954 0.37220829725265503 0.2579218149185181 0.0608430877327919 2.069700002670288 2.495539903640747 1.2778400182724 -0.852620005607605 37.216746602395524 35.0 0.0 no 10290 chrXIII_369505 27427 essential YMR049C 993 - TAACTCTCTTCATTAGTTGG S|337|T S|337|N E|336|D silent|GAG>GAA|E|336 ERB1 Eukaryotic Ribosome Biogenesis 807.0 0 0 0 0 -1.4265345840827008 Q04660 0.9512869715690612 0.9536849856376648 0.94931298494339 0.0 0.0 0.09593208879232408 42.38190578824555 35.0 0.0 no 10291 chrXIII_369508 27428 essential YMR049C 990 - CTCTCTTCATTAGTTGGTGG E|336|D silent|GAG>GAA|E|336 E|336|Q E|336|K ERB1 Eukaryotic Ribosome Biogenesis 807.0 0 0 0 0 -0.4831367115148314 Q04660 0.94931298494339 0.956179976463318 0.9475290179252625 0.09593208879232408 0.06360979378223419 0.06439579278230667 49.582940101163956 45.0 0.0 no 10292 chrXIII_369583r 27429 essential YMR049C 912 + AACTATCAATACGATTTATG N|305|K silent|AAC>AAT|N|305 Q|307|E Q|307|* ERB1 Eukaryotic Ribosome Biogenesis 807.0 0 0 0 0 -0.6508310033611283 Q04660 0.9439849853515624 0.9590039849281312 0.9050114154815674 0.3012523353099823 33.33140605890304 25.0 0.0 no 10293 chrXIII_369584r 27430 essential YMR049C 911 + AAACTATCAATACGATTTAT N|305|K silent|AAC>AAT|N|305 ERB1 Eukaryotic Ribosome Biogenesis 807.0 0 0 0 0 -0.0905992896290068 Q04660 0.9439849853515624 0.9050114154815674 32.15400737097804 20.0 0.0 no 10294 chrXIII_369678 27431 essential YMR049C 820 - TACAATTTTCATAACTCTCT V|280|L V|280|I ERB1 Eukaryotic Ribosome Biogenesis 807.0 0 0 0 0 0.650874901113014 Q04660 0.9539830088615416 0.9574310183525084 0.014798224903643131 0.021145211532711983 37.72487480743007 25.0 0.0 no 10295 chrXIII_369690 27432 essential YMR049C 808 - AACTCTCTTGGCTTCGTTTT V|276|L V|276|I R|275|T R|275|K ERB1 Eukaryotic Ribosome Biogenesis 807.0 0 0 0 0 0.2199848114874692 Q04660 0.9539830088615416 0.9574310183525084 0.932735025882721 0.955805003643036 0.0315624438226223 0.5596121549606323 0.012351900339126587 1.0 49.678341929116705 40.0 0.0 no 10296 chrXIII_369772 27433 essential YMR049C 726 - CTCGTGAACCAATCGATTAA silent|ACG>ACC|T|248 silent|ACG>ACA|T|248 ERB1 Eukaryotic Ribosome Biogenesis 807.0 0 0 0 0 0.18081930906649246 Q04660 41.53641144612766 40.0 0.0 no 10297 chrXIII_369938r 27436 essential YMR049C 557 + TTCTGCTTTAGATCAACTGT S|187|C S|187|F A|188|G A|188|V ERB1 Eukaryotic Ribosome Biogenesis 807.0 0 0 0 0 0.026471103430737525 Q04660 0.945252001285553 0.9294660091400146 0.9484469890594482 0.9504740238189696 0.0009425209136679767 0.0030278433114290237 0.19502267241477966 0.0906805619597435 44.54769138186315 35.0 0.0 no 10298 chrXIII_369949 27437 essential YMR049C 549 - TCTAAAGCAGAACCCTTGGC D|190|H D|190|N ERB1 Eukaryotic Ribosome Biogenesis 807.0 0 0 0 0 -0.4350562175711969 Q04660 0.9486550092697144 0.956179976463318 0.0027455531526356936 0.008683914318680763 49.222984049049046 50.0 0.0 no 10299 chrXIII_369988r 27438 essential YMR049C 507 + CACATTGGATACGATATCAA H|170|Q silent|CAC>CAT|H|170 ERB1 Eukaryotic Ribosome Biogenesis 807.0 0 1 0 0 -0.5592480291739729 Q04660 0.9588389992713928 0.0 39.09521987651567 35.0 0.0 no 10300 chrXIII_370003r 27439 essential YMR049C 492 + TACGATGAAATGCCACACAT Y|165|* silent|TAC>TAT|Y|165 ERB1 Eukaryotic Ribosome Biogenesis 807.0 0 0 0 0 -1.2016770932699314 Q04660 42.31530707794785 40.0 0.0 no 10301 chrXIII_370084 27440 essential YMR049C 414 - TCATAAACTGGATTAATTTC D|145|H D|145|N ERB1 Eukaryotic Ribosome Biogenesis 807.0 0 0 0 0 -0.6309368161655735 Q04660 0.9486550092697144 0.956179976463318 0.08751299232244493 0.5458845496177673 33.85316571573901 25.0 0.0 no 10302 chrXIII_370132 27441 essential YMR049C 366 - GCATATTTTGAGTAAATATT A|129|P A|129|T ERB1 Eukaryotic Ribosome Biogenesis 807.0 0 1 0 0 0.4538615186915744 Q04660 0.9573720097541808 0.9523990154266356 0.08402016013860703 0.2524009943008423 34.389592436692055 20.0 0.0 no 10303 chrXIII_370408r 27443 essential YMR049C 87 + GACAAGCTTTTATCCGTTGA D|30|E silent|GAC>GAT|D|30 L|32|V L|32|F ERB1 Eukaryotic Ribosome Biogenesis 807.0 0 0 0 0 0.03191176625142442 Q04660 0.9532920122146606 0.9512209892272948 0.9587849974632264 1.0 0.2981535792350769 0.06802643090486526 46.438727899203464 40.0 0.0 no 10304 chrXIII_369815 27446 essential YMR049C 683 - CATCAGTTTGTTCGTTCCTT D|234|H D|234|N ERB1 Eukaryotic Ribosome Biogenesis 807.0 0 0 0 0 0.2451934390177353 Q04660 0.9486550092697144 0.956179976463318 0.009144149720668793 0.08808983862400055 51.023804270094566 40.0 0.0 no 10305 chrXIII_391149r 27448 essential YMR059W 53 - TTTCCACTTCCGTCCACATT E|24|Q E|24|K silent|GTG>GTC|V|23 silent|GTG>GTA|V|23 SEN15 Splicing ENdonuclease 128.0 0 0 0 0 0.5591795990307827 Q04675 0.956179976463318 0.9475290179252625 0.31668931245803833 0.5126171112060547 54.923978954624936 45.0 1.0 no 10306 chrXIII_391228r 27450 essential YMR059W 132 - TCGTTGCTCAGCTTGTGAGG D|51|H D|51|N S|49|T S|49|N SEN15 Splicing ENdonuclease 128.0 0 0 0 0 0.6247703940031841 Q04675 0.9486550092697144 0.956179976463318 0.9512869715690612 0.9536849856376648 0.013085003942251205 0.06674038618803024 0.6945579648017883 0.12057587504386902 54.58845800398302 55.00000000000001 1.0 no 10307 chrXIII_391362r 27452 essential YMR059W 266 - TACATAAGTGAGTAAATGTC C|95|S C|95|Y SEN15 Splicing ENdonuclease 128.0 0 0 0 0 1.0641183534808043 Q04675 0.9421560168266296 0.9290120005607604 0.45402592420578 1.0 34.508834473290854 30.0 1.0 no 10308 chrXIII_391892 27457 high_effect YMR060C 604 - GTTCTTATGCGCAATTTTGA K|207|N silent|AAG>AAA|K|207 SAM37 Sorting and Assembly Machinery 327.0 0 0 0 0 0.25878298385613563 P50110 0.9579749703407288 0.3659403920173645 44.815852003045855 35.0 0.0 no 10309 chrXIII_392809 27465 essential YMR061W 54 + GAGCCTAGTGACAATATACA P|20|A P|20|S P|20|R P|20|L RNA14 poly(A) mRNA metabolism 677.0 0 0 0 0 -0.2886594356721285 P25298 0.8125425577163696 0.6455293297767639 0.4515847861766815 0.3975324630737305 43.93459647269884 40.0 1.0 no 10310 chrXIII_392913 27466 essential YMR061W 158 + AACTCAAGAGTCATACGCTA T|54|S T|54|I Q|55|E Q|55|* RNA14 poly(A) mRNA metabolism 677.0 0 0 0 0 0.5726012848419318 P25298 0.8865677118301392 0.18974392116069794 0.3202422261238098 42.96244897347208 40.0 1.0 no 10311 chrXIII_392892r 27467 essential YMR061W 140 - TTTCCAAATATTGAATAAGC E|53|Q E|53|K L|52|F silent|TTG>TTA|L|52 RNA14 poly(A) mRNA metabolism 677.0 0 0 0 0 -0.5114356337766995 P25298 0.5938664078712463 0.9189639687538148 0.6798627376556396 34.66557016623284 25.0 1.0 no 10312 chrXIII_392985 27469 essential YMR061W 230 + TGCGTGGACTTTGCAACTAA A|78|G A|78|V RNA14 poly(A) mRNA metabolism 677.0 0 0 0 0 0.26753196872266755 P25298 0.3913772702217102 0.4939319789409638 46.53460775038542 45.0 1.0 no 10313 chrXIII_393090 27471 essential YMR061W 335 + ATCTCTTTGGTCAACATATT S|113|C S|113|F L|114|V L|114|F RNA14 poly(A) mRNA metabolism 677.0 0 1 0 0 0.7980199823057417 P25298 0.04081609472632408 0.04277748987078667 0.183944433927536 0.03003322146832943 42.3979454348509 30.0 1.0 no 10314 chrXIII_393183r 27473 essential YMR061W 431 - CACACTTTTGCATAACTAGT C|150|S C|150|Y K|149|N silent|AAG>AAA|K|149 RNA14 poly(A) mRNA metabolism 677.0 0 0 0 0 0.3964439626839051 P25298 0.03559928387403488 0.021449951454997063 0.27373480796813965 42.51164354836345 35.0 1.0 no 10315 chrXIII_393413r 27474 essential YMR061W 661 - TAACTCGCCAATAAATTTTC E|226|D silent|GAG>GAA|E|226 E|226|Q E|226|K RNA14 poly(A) mRNA metabolism 677.0 0 0 0 0 0.7276991843812017 P25298 0.19478115439414975 0.03510979935526848 0.02820615842938423 37.80462429970231 30.0 1.0 no 10316 chrXIII_393461r 27477 essential YMR061W 709 - GTTCAACCATTCCTGGTATA L|242|F silent|TTG>TTA|L|242 W|241|C W|241|* RNA14 poly(A) mRNA metabolism 677.0 0 0 0 0 0.04113206686966653 P25298 0.5835310816764832 0.0850132405757904 49.157760884904526 40.0 1.0 no 10317 chrXIII_393572 27479 essential YMR061W 817 + ACATTCAGCAGTTACAGATT N|273|K silent|AAC>AAT|N|273 Q|275|E Q|275|* RNA14 poly(A) mRNA metabolism 677.0 0 0 0 0 0.7901159889532214 P25298 0.35725611448287964 0.71998131275177 44.11850120925749 35.0 1.0 no 10318 chrXIII_393909 27480 essential YMR061W 1154 + GATCGCCTCCGATGTAAATT I|386|M silent|ATC>ATT|I|386 A|387|G A|387|V RNA14 poly(A) mRNA metabolism 677.0 0 0 0 0 0.01897691587250261 P25298 0.09589916467666626 0.3728210628032684 0.28219354152679443 48.04646886156337 45.0 1.0 no 10319 chrXIII_393914r 27482 essential YMR061W 1162 - TTCACCCGAATTTACATCGG E|394|Q E|394|K G|393|A G|393|D RNA14 poly(A) mRNA metabolism 677.0 0 0 0 0 0.2578319980349347 P25298 0.3282163441181183 0.689764678478241 0.7822073698043823 0.6293420791625977 46.911051748756115 45.0 1.0 no 10320 chrXIII_394042 27483 essential YMR061W 1287 + TCCGCAGCACGTACTGTATT silent|TCC>TCG|S|430 silent|TCC>TCT|S|430 S|430|C S|430|F RNA14 poly(A) mRNA metabolism 677.0 0 0 0 0 0.7119116466774721 P25298 0.03770250454545021 0.03740976005792618 53.20530250823038 50.0 1.0 no 10321 chrXIII_394043r 27484 essential YMR061W 1291 - ACCAAATACAGTACGTGCTG G|437|R G|437|S G|437|A G|437|D RNA14 poly(A) mRNA metabolism 677.0 0 0 0 0 0.4990021267618293 P25298 0.2615710198879242 0.7020489573478699 0.91789573431015 0.31067004799842834 44.67671996089582 45.0 1.0 no 10322 chrXIII_394155 27485 essential YMR061W 1400 + TGCTTTTAAGGTTTTAGAAT A|468|G A|468|V RNA14 poly(A) mRNA metabolism 677.0 0 0 0 0 -0.5125527649495488 P25298 0.13049252331256864 0.045510679483413696 38.247093756794015 25.0 1.0 no 10323 chrXIII_417145 27487 essential YMR076C 2865 - TCCAAAAATGTTTTTCTTAC L|961|F silent|TTG>TTA|L|961 E|962|Q E|962|K PDS5 Precocious Dissociation of Sisters 1277.0 0 0 0 0 -0.13382618435624394 Q04264 0.06261647492647171 0.5856502652168274 0.9217951893806458 36.21059247499186 25.0 0.0 no 10324 chrXIII_417209r 27488 essential YMR076C 2798 + GAACAACTTTATCAAACCTT N|934|K silent|AAC>AAT|N|934 N|935|K silent|AAC>AAT|N|935 PDS5 Precocious Dissociation of Sisters 1277.0 0 0 0 0 0.8262951218708088 Q04264 0.04871440306305885 1.0 37.650916161127036 30.0 0.0 no 10325 chrXIII_417320r 27492 essential YMR076C 2687 + GCTGATTTCCGAGTTTAACA L|897|V silent|CTG>TTG|L|897 PDS5 Precocious Dissociation of Sisters 1277.0 0 0 0 0 0.44080853078189003 Q04264 0.4242745935916901 46.438727899203464 40.0 0.0 no 10326 chrXIII_417349r 27493 essential YMR076C 2658 + TTCTTTTACTTGATTGCAAG F|887|L silent|TTC>TTT|F|887 PDS5 Precocious Dissociation of Sisters 1277.0 0 0 0 0 0.8806952994166469 Q04264 1.0 39.91148727989906 30.0 0.0 no 10327 chrXIII_417608 27495 essential YMR076C 2402 - AATCATCATTTAGGACGTGA D|807|H D|807|N D|806|H D|806|N PDS5 Precocious Dissociation of Sisters 1277.0 0 0 0 0 -0.3017147967325178 Q04264 0.10890103876590727 0.3440035283565521 0.07744904607534409 0.296565443277359 41.37110199794886 35.0 0.0 no 10328 chrXIII_417647r 27496 essential YMR076C 2360 + ATCTCATATTATTGTACTCA S|788|C S|788|F H|789|D H|789|Y PDS5 Precocious Dissociation of Sisters 1277.0 0 0 0 0 -0.7153175332130182 Q04264 0.00963372178375721 0.0054451078176498404 0.609004020690918 0.4051166772842407 39.93989875393794 25.0 0.0 no 10329 chrXIII_417724 27497 essential YMR076C 2286 - TTCAGAGTTTCTTCAGCTTT silent|CTG>CTC|L|768 silent|CTG>CTA|L|768 PDS5 Precocious Dissociation of Sisters 1277.0 0 0 0 0 0.6092251213940196 Q04264 47.98033130695882 35.0 0.0 no 10330 chrXIII_417846 27499 essential YMR076C 2164 - CACTTGATCCTTTAATGTTT V|728|L V|728|M PDS5 Precocious Dissociation of Sisters 1277.0 0 0 0 0 -0.031385981798578814 Q04264 1.0 0.23608161509037015 42.3877734017874 30.0 0.0 no 10331 chrXIII_417872r 27500 essential YMR076C 2135 + AGCTTTAAAAACCCTTTACA A|713|G A|713|V PDS5 Precocious Dissociation of Sisters 1277.0 0 0 0 0 0.5707757310474013 Q04264 0.2709907591342926 0.3158707618713379 40.709477291508726 30.0 0.0 no 10332 chrXIII_417944r 27501 essential YMR076C 2063 + AACATTAAAAACCATTATCA T|689|R T|689|I PDS5 Precocious Dissociation of Sisters 1277.0 0 0 0 0 0.21875775422976634 Q04264 0.4603173434734345 0.16524231433868408 5.999999848427251e-05 -0.2879599928855896 32.35989174145618 20.0 0.0 no 10333 chrXIII_418065 27502 essential YMR076C 1945 - GTTCAATAAAACACTGATGT L|654|F silent|TTG>TTA|L|654 PDS5 Precocious Dissociation of Sisters 1277.0 0 0 0 0 0.17934730691539152 Q04264 0.157144695520401 -0.5033400058746338 35.873793273601386 30.0 0.0 no 10334 chrXIII_418089 27503 essential YMR076C 1921 - TACATTATAAATTATTGGTG V|647|L V|647|I PDS5 Precocious Dissociation of Sisters 1277.0 0 0 0 0 0.8464364714910657 Q04264 0.33618202805519104 0.21723996102809906 -0.4793800115585327 -0.026879999786615368 31.832071563606462 20.0 0.0 no 10335 chrXIII_418697 27511 essential YMR076C 1313 - TTTCCCAAATTTCTTTATTT E|444|Q E|444|K W|443|C W|443|* PDS5 Precocious Dissociation of Sisters 1277.0 0 0 0 0 -0.37369598194787984 Q04264 0.4931171536445618 0.6902089715003967 0.09482575953006744 -0.3132799863815308 -0.403439998626709 2.2523601055145264 40.60269922720863 20.0 0.0 no 10336 chrXIII_418902r 27514 essential YMR076C 1105 + ATTCTGATCCTCGTGTACGC S|370|C S|370|F PDS5 Precocious Dissociation of Sisters 1277.0 0 0 0 0 -0.2076637524346323 Q04264 0.008143175393342972 0.0042640650644898415 -0.05897999927401543 0.12319999933242798 52.20774210636751 50.0 0.0 no 10337 chrXIII_419049 27516 essential YMR076C 961 - AATCCATGCCTTGAACGTAT W|326|C W|326|* W|326|S W|326|* PDS5 Precocious Dissociation of Sisters 1277.0 0 0 0 0 0.6660452454347711 Q04264 0.0 0.0 6.123300075531006 7.141560077667236 46.557971240565045 40.0 0.0 no 10338 chrXIII_419057r 27518 essential YMR076C 950 + TACACATTCCGATACGTTCA T|318|R T|318|I H|319|D H|319|Y PDS5 Precocious Dissociation of Sisters 1277.0 0 0 0 0 0.17659670759740592 Q04264 0.05316437780857086 0.4120679497718811 0.0 0.0 -0.6357799768447876 -0.0068199997767806044 2.69655990600586 -2.1181399822235107 45.849648988253826 40.0 0.0 no 10339 chrXIII_419096r 27519 essential YMR076C 911 + TCAAATACTTACCTCATATT Q|305|E Q|305|* PDS5 Precocious Dissociation of Sisters 1277.0 0 0 0 0 0.4806100041913348 Q04264 0.4188147485256195 0.4564000070095062 38.203938795308375 25.0 0.0 no 10340 chrXIII_419759 27526 essential YMR076C 251 - CATCTGGAGCATATAATCTC D|90|H D|90|N PDS5 Precocious Dissociation of Sisters 1277.0 0 0 0 0 0.05497906702430155 Q04264 0.028376286849379536 0.09723521769046783 -0.7081599831581116 -0.7726600170135498 43.06376984286204 40.0 0.0 no 10341 chrXIII_419747r 27527 essential YMR076C 260 + TGCTCCAGATGCGCCTTATA A|88|G A|88|V P|89|A P|89|S PDS5 Precocious Dissociation of Sisters 1277.0 0 0 0 0 -2.9685338737948066 Q04264 0.0 0.0 0.0 0.0 -0.08420000225305557 1.2839399576187134 1.258139967918396 1.3074599504470823 55.14534994911367 50.0 0.0 yes 10342 chrXIII_423101 27532 high_effect YMR078C 1608 - TCCGTAAAACTTGCCATTAG silent|ACG>ACC|T|542 silent|ACG>ACA|T|542 D|543|H D|543|N CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 0.9750318275687394 P49956 0.9486550092697144 0.956179976463318 0.024307603016495705 1.0 43.85488107264172 40.0 0.0 no 10343 chrXIII_423102 27533 high_effect YMR078C 1607 - CCGTAAAACTTGCCATTAGT silent|ACG>ACC|T|542 silent|ACG>ACA|T|542 CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 -0.6110035396074488 P49956 45.25797224455914 40.0 0.0 no 10344 chrXIII_423114r 27534 high_effect YMR078C 1592 + CTCGGTTCAGTCCCCACTAA S|532|W S|532|L CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 0.6125291077873204 P49956 0.9288619756698608 0.9298099875450134 0.04743259400129318 0.40114206075668335 57.09572763067274 55.00000000000001 0.0 no 10345 chrXIII_423244 27538 high_effect YMR078C 1465 - AAACGTTTGGAAGAAGACTA silent|ACG>ACC|T|494 silent|ACG>ACA|T|494 CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 -0.11673294029523948 P49956 36.486609394407026 35.0 0.0 no 10346 chrXIII_423361 27539 high_effect YMR078C 1348 - TGGCTTTCTTATACCATTGT K|455|N silent|AAG>AAA|K|455 CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 0.3598200859766694 P49956 0.9355990290641784 0.0 48.07143068068734 35.0 0.0 no 10347 chrXIII_423374r 27540 high_effect YMR078C 1332 + TACGTAAAATATTCCGACAA Y|445|* silent|TAC>TAT|Y|445 CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 -0.2129388864436083 P49956 36.319113414211024 30.0 0.0 no 10348 chrXIII_423427r 27541 high_effect YMR078C 1279 + AGCTTAATGGTAACTCTGAC L|428|V L|428|F CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 0.09934420202538123 P49956 0.9512209892272948 0.9587849974632264 0.9545705318450928 0.15822719037532804 42.468312385648346 40.0 0.0 no 10349 chrXIII_423532r 27545 high_effect YMR078C 1174 + ACAAGGACTCCCCCATATCA N|392|K silent|AAC>AAT|N|392 CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 0.019622836199425286 P49956 0.9439849853515624 0.9157967567443848 54.20060557055086 50.0 0.0 no 10350 chrXIII_423564r 27546 high_effect YMR078C 1142 + TGCTTGTGCAAAAAATACGT A|382|G A|382|V CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 0.02802527556134937 P49956 0.9484469890594482 0.9504740238189696 0.3983671963214874 0.33865830302238464 39.11705778259801 35.0 0.0 no 10351 chrXIII_423583 27548 high_effect YMR078C 1126 - AGCAGGTTTATCTGATGCAG A|382|P A|382|T CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 -0.34865949613966685 P49956 0.9573720097541808 0.9523990154266356 0.2884524464607239 0.6797393560409546 48.49413740442111 45.0 0.0 no 10352 chrXIII_423668r 27549 high_effect YMR078C 1038 + GACTTAATTGATTTGGCTCA D|347|E silent|GAC>GAT|D|347 CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 0.7464399219231143 P49956 0.9532920122146606 1.0 43.01189509439269 35.0 0.0 no 10353 chrXIII_423675r 27550 high_effect YMR078C 1031 + AATCAATGACTTAATTGATT I|345|M silent|ATC>ATT|I|345 CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 -0.4231426052664815 P49956 0.9598389863967896 0.02952728606760502 32.57275960244885 20.0 0.0 no 10354 chrXIII_423745 27551 high_effect YMR078C 964 - TCGCTCTAGTAGGGTAGTAT E|327|D silent|GAG>GAA|E|327 R|328|P R|328|Q CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 -1.2787033668571333 P49956 0.94931298494339 0.9099509716033936 0.949662983417511 0.1176680624485016 0.0 0.0 50.65207067660373 45.0 0.0 no 10355 chrXIII_423779 27553 high_effect YMR078C 930 - ACAGCAATAATTTCACAGAA V|317|L V|317|M A|316|P A|316|T CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 0.04413915898732043 P49956 0.9539830088615416 0.9587630033493042 0.9573720097541808 0.9523990154266356 0.5184627175331116 0.06363316625356674 0.2863087654113769 1.0 37.114731929149855 30.0 0.0 no 10356 chrXIII_423874r 27554 high_effect YMR078C 832 + ACAAAAAGCGCAAAAAGAAA D|278|E silent|GAC>GAT|D|278 CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 0.25192022243316003 P49956 0.9532920122146606 0.7104001641273499 30.71179604567357 30.0 0.0 no 10357 chrXIII_423913 27555 high_effect YMR078C 796 - ACCGTATAATAGTTTATTAG G|272|R G|272|S G|272|A G|272|D CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 0.1471031505884438 P49956 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.7705656886100769 0.5180205702781677 0.6512518525123596 0.4723789691925049 36.50959446326215 25.0 0.0 no 10358 chrXIII_423914r 27556 high_effect YMR078C 792 + GCCACTAATAAACTATTATA silent|GCC>GCG|A|265 silent|GCC>GCT|A|265 A|265|G A|265|V CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 0.27373207370962155 P49956 0.9484469890594482 0.9504740238189696 0.0 0.0 36.12759731263998 25.0 0.0 no 10359 chrXIII_424004 27557 high_effect YMR078C 705 - TCATCCGCCACTAAGCACAC E|242|Q E|242|K D|241|H D|241|N CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 -0.1287682254370498 P49956 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.0 0.0 0.0 0.0 53.30573505736328 55.00000000000001 0.0 no 10360 chrXIII_424011r 27558 high_effect YMR078C 695 + TACAAATCCTGTGTGCTTAG T|233|R T|233|I CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 0.4087476170784306 P49956 0.9476869702339172 0.9472420215606691 0.4591366052627564 0.1627081334590912 44.304277923240825 40.0 0.0 no 10361 chrXIII_424117 27559 high_effect YMR078C 592 - GACAGAAAACCCTGATTGTT V|204|L V|204|I CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 0.34730355347201325 P49956 0.9539830088615416 0.9574310183525084 0.0382826030254364 0.2810598015785217 43.201689572460346 40.0 0.0 no 10362 chrXIII_424126r 27560 high_effect YMR078C 580 + ACGTTATTGCCAAACAATCA H|194|Q silent|CAC>CAT|H|194 CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 0.8166693617519123 P49956 0.9588389992713928 0.0 41.9524752180057 35.0 0.0 no 10363 chrXIII_424127r 27561 high_effect YMR078C 579 + CACGTTATTGCCAAACAATC H|194|Q silent|CAC>CAT|H|194 CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 0.1729469118037789 P49956 0.9588389992713928 0.0 41.952475218005645 40.0 0.0 no 10364 chrXIII_424199 27566 high_effect YMR078C 510 - TTCTTTGGTGGCCTTTTCAA K|176|N silent|AAG>AAA|K|176 CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 0.8511557067552122 P49956 0.9355990290641784 0.0 51.220772423670155 40.0 0.0 no 10365 chrXIII_424243 27567 high_effect YMR078C 466 - CTCTTTTTCGGTTGGCAATT E|162|Q E|162|K CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 -0.24470434166321745 P49956 0.956179976463318 0.9475290179252625 0.527485728263855 0.8511412739753723 48.410205222494604 40.0 0.0 no 10366 chrXIII_424244 27568 high_effect YMR078C 465 - TCTTTTTCGGTTGGCAATTT E|162|Q E|162|K CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 1.8262513491046253 P49956 0.956179976463318 0.9475290179252625 0.527485728263855 0.8511412739753723 46.84702835255615 35.0 0.0 no 10367 chrXIII_424394 27569 high_effect YMR078C 315 - CTACCTATCTTGCCAGTTAT G|111|A G|111|D G|111|R G|111|S CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 0.13725621147859055 P49956 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 1.0 0.5695984959602356 0.5272231698036194 0.8694422841072083 50.35260579266549 40.0 0.0 no 10368 chrXIII_424510r 27571 high_effect YMR078C 196 + ACACTAACCCAGATACTGTT T|67|S T|67|I Y|66|* silent|TAC>TAT|Y|66 CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 -0.5663998822589422 P49956 0.9491789937019348 0.9472420215606691 0.6148792505264282 0.16747799515724182 46.32866787279272 40.0 0.0 no 10369 chrXIII_424592r 27573 high_effect YMR078C 114 + CACGCGTTTGTATCAAGTAC H|39|Q silent|CAC>CAT|H|39 A|40|G A|40|V CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 0.11250981653887583 P49956 0.9588389992713928 0.9484469890594482 0.9504740238189696 0.6653187870979309 0.370678573846817 0.5363203883171082 45.34424616537592 45.0 0.0 no 10370 chrXIII_424631 27574 high_effect YMR078C 78 - ATACCAATTGCATTATTACC G|32|A G|32|D G|32|R G|32|S CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 -0.32146211385735635 P49956 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.40258443355560297 0.6101707220077515 0.26389265060424805 0.35504549741744995 41.81082616922805 30.0 0.0 no 10371 chrXIII_423549r 27576 high_effect YMR078C 1157 + TACGTGGGCGTCATCCAACA T|387|R T|387|M CTF18 Chromosome Transmission Fidelity 741.0 0 0 0 0 -1.5859890700109447 P49956 0.9476869702339172 0.9502379894256592 53.2077879765622 55.00000000000001 0.0 no 10372 chrXIII_454078r 27582 essential YMR093W 66 - TGACGCCAGTAACGCTGCTC R|28|P R|28|H W|27|C W|27|* UTP15 U Three Protein 513.0 0 0 0 0 -0.8642978659730428 Q04305 0.9099509716033936 0.9570810198783876 0.8858469724655151 0.05679227039217949 0.06065628677606584 0.0 54.47187484387553 60.0 1.0 no 10373 chrXIII_454098 27583 essential YMR093W 83 + TCAATACACTTCCGCACAAC Q|29|E Q|29|* Y|30|* silent|TAC>TAT|Y|30 UTP15 U Three Protein 513.0 0 0 0 0 0.5762443087033938 Q04305 0.9590039849281312 0.531394362449646 45.37659921524556 45.0 1.0 no 10374 chrXIII_454307r 27585 essential YMR093W 295 - CACTAAACCGGTAGCATCAC V|105|L V|105|M UTP15 U Three Protein 513.0 0 0 0 0 -1.7572659060649418 Q04305 0.9539830088615416 0.9587630033493042 0.07739105075597763 0.014430091716349125 46.7218792978656 50.0 1.0 no 10375 chrXIII_454448 27587 essential YMR093W 433 + ACGATAGAGTGACAAGACTT D|145|E silent|GAC>GAT|D|145 UTP15 U Three Protein 513.0 0 0 0 0 0.9424035497111632 Q04305 0.9532920122146606 0.0 40.73125416169 40.0 1.0 no 10376 chrXIII_454542 27592 essential YMR093W 527 + TATCCCAGCAGCCCCACATT I|177|M silent|ATC>ATT|I|177 P|178|A P|178|S UTP15 U Three Protein 513.0 0 0 0 0 0.5428607140329841 Q04305 0.9598389863967896 0.9562489986419678 0.9498909711837769 0.3078979253768921 0.38347843289375305 0.2202717661857605 61.36267315756203 55.00000000000001 1.0 no 10377 chrXIII_454553r 27595 essential YMR093W 541 - GCCTGTTGCAACCAAATGTG G|187|R G|187|S G|187|A G|187|D UTP15 U Three Protein 513.0 0 0 0 0 -0.9419976028259374 Q04305 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 49.475242214550526 50.0 1.0 no 10378 chrXIII_454733r 27599 essential YMR093W 721 - TTCGTATAATTTCTTGTTAC E|247|Q E|247|K UTP15 U Three Protein 513.0 0 0 0 0 0.6312910292994418 Q04305 0.956179976463318 0.9475290179252625 0.6122740507125854 0.8769970536231995 37.652407230831564 25.0 1.0 no 10379 chrXIII_454654r 27600 essential YMR093W 642 - ACTGCAATAACATTTTCAAC V|221|L V|221|I A|220|P A|220|T UTP15 U Three Protein 513.0 0 1 0 0 0.4485106497625153 Q04305 0.9539830088615416 0.9574310183525084 0.9573720097541808 0.9523990154266356 0.44559699296951294 1.0 0.2339962869882584 0.4874694347381592 37.03162828210049 30.0 1.0 no 10380 chrXIII_454841r 27603 essential YMR093W 829 - GACTTTGACATGACCATCTA V|283|L V|283|I UTP15 U Three Protein 513.0 0 0 0 0 -0.5654358287532241 Q04305 0.9539830088615416 0.9574310183525084 0.06961323320865631 0.6888362169265747 45.233619103322276 40.0 1.0 no 10381 chrXIII_454876 27604 essential YMR093W 861 + GACAATTTCCAAGTCAAATT D|288|E silent|GAC>GAT|D|288 UTP15 U Three Protein 513.0 0 0 0 0 -0.404351196464315 Q04305 0.9532920122146606 0.8788248300552368 38.295434904411024 30.0 1.0 no 10382 chrXIII_454933 27605 essential YMR093W 918 + GTCTCCCCTAGTACCGCACA silent|GTC>GTG|V|307 silent|GTC>GTT|V|307 S|308|C S|308|F UTP15 U Three Protein 513.0 0 0 0 0 0.6162197501421417 Q04305 0.945252001285553 0.9294660091400146 0.0 0.0 62.305912287767455 60.0 1.0 no 10383 chrXIII_454937r 27606 essential YMR093W 925 - ATTCCCTTGTGCGGTACTAG silent|GGG>GGC|G|314 silent|GGG>GGA|G|314 G|314|A G|314|E UTP15 U Three Protein 513.0 0 0 0 0 -1.176491417889223 Q04305 0.9499930143356324 0.9438679814338684 53.842422466712954 50.0 1.0 no 10384 chrXIII_454934 27607 essential YMR093W 919 + TCTCCCCTAGTACCGCACAA S|308|C S|308|F silent|GTC>GTG|V|307 silent|GTC>GTT|V|307 UTP15 U Three Protein 513.0 0 0 0 0 -0.07651027036943077 Q04305 0.945252001285553 0.9294660091400146 0.0 0.0 57.718641091636236 55.00000000000001 1.0 no 10385 chrXIII_455048r 27610 essential YMR093W 1036 - CGCATTCTTATTAAAACTGG A|352|P A|352|T K|350|N silent|AAG>AAA|K|350 UTP15 U Three Protein 513.0 0 0 0 0 0.5591233035711312 Q04305 0.9573720097541808 0.9523990154266356 0.9355990290641784 0.2795094847679138 0.5626555681228638 0.3051443099975586 38.523967851246255 35.0 1.0 no 10386 chrXIII_455051r 27611 essential YMR093W 1039 - TTTCGCATTCTTATTAAAAC silent|GCG>GCC|A|352 silent|GCG>GCA|A|352 A|352|P A|352|T UTP15 U Three Protein 513.0 0 0 0 0 0.031925907129070084 Q04305 0.9573720097541808 0.9523990154266356 0.2795094847679138 0.5626555681228638 35.79645063910374 25.0 1.0 no 10387 chrXIII_455127 27616 essential YMR093W 1112 + GCATATAATCCACAATGATA H|372|D H|372|Y UTP15 U Three Protein 513.0 0 0 0 0 1.0935985851746564 Q04305 0.9473130106925964 0.9489949941635132 0.9551172256469728 0.052368704229593284 38.93156630512618 30.0 1.0 no 10388 chrXIII_455861r 27618 essential YMR094W 39 - ACTTCTTTTCTAATGTCAAT V|20|L V|20|I E|19|Q E|19|K 0 0 0 0 0.6935629230304509 P35203 0.9539830088615416 0.9574310183525084 0.956179976463318 0.9475290179252625 0.052541878074407584 0.2719411253929138 0.4551060795783997 0.6415929794311523 39.16911869826328 25.0 1.0 no 10389 chrXIII_455890r 27619 essential YMR094W 68 - CGCAAAAATTACCATCTAAA C|29|S C|29|Y 0 0 0 0 0.6541588852504518 P35203 0.9421560168266296 0.9290120005607604 0.6958034038543701 0.052922140806913376 35.579092798208706 30.0 1.0 no 10390 chrXIII_456026r 27621 essential YMR094W 204 - TTCAAATACGTGGCAAAAAC L|74|F silent|TTG>TTA|L|74 0 0 0 0 1.0292680769753182 P35203 0.9587849974632264 0.031080830842256543 35.508430590871065 35.0 1.0 no 10391 chrXIII_455975r 27622 essential YMR094W 153 - CTCTTAGACCTTTTATAACT K|57|N silent|AAG>AAA|K|57 0 0 0 0 0.2667727003993533 P35203 0.9355990290641784 0.03714141994714737 41.31998717265725 30.0 1.0 no 10392 chrXIII_456190 27624 essential YMR094W 365 + CCTTGATAATGAACTTCGAC L|123|V L|123|F 0 0 0 0 0.8968837181809681 P35203 0.9512209892272948 0.9587849974632264 0.05197305977344513 0.03136218339204788 40.682914726076774 40.0 1.0 no 10393 chrXIII_456162 27625 essential YMR094W 337 + CGCTTATAGATGCATTAGAA L|114|V L|114|F 0 0 0 0 -0.4017964254596444 P35203 0.9512209892272948 0.9587849974632264 0.04938946291804314 0.03050320595502853 40.8889649909196 35.0 1.0 no 10394 chrXIII_456190r 27626 essential YMR094W 368 - CCAGTCGAAGTTCATTATCA silent|CTG>CTC|L|129 silent|CTG>CTA|L|129 R|128|P R|128|Q 0 0 0 0 -1.920159672330383 P35203 0.9099509716033936 0.949662983417511 0.018763909116387367 0.21982847154140472 46.02131917486514 40.0 1.0 no 10395 chrXIII_456228r 27628 essential YMR094W 406 - ATACCAAACTTCTAACATAC W|141|C W|141|* W|141|S W|141|* 0 0 0 0 0.05674649593031687 P35203 0.8858469724655151 0.8858469724655151 0.0 0.0 36.69875087814109 30.0 1.0 no 10396 chrXIII_456353r 27629 essential YMR094W 531 - AAGCATTTGTCTACTAGTTG C|183|S C|183|Y 0 0 0 0 0.9422611461466796 P35203 0.9421560168266296 0.9290120005607604 0.11085613816976547 0.08880756050348282 42.43786111138973 35.0 1.0 no 10397 chrXIII_456547 27632 essential YMR094W 722 + ACATTCAGATAATGGCAATG H|242|D H|242|Y S|243|* S|243|L 0 0 0 0 0.14415713017288465 P35203 0.9473130106925964 0.9489949941635132 0.9298099875450134 0.1169067993760109 0.4200032353401184 0.3360057473182678 38.79290305982357 35.0 1.0 no 10398 chrXIII_456630r 27634 essential YMR094W 808 - GATCTTCCGCAGGCTCTTCA K|275|N silent|AAG>AAA|K|275 silent|CGG>CGC|R|274 silent|CGG>CGA|R|274 0 0 0 0 -0.2767064000318857 P35203 0.9355990290641784 0.3878913223743439 58.339679176240786 55.00000000000001 1.0 no 10399 chrXIII_456640r 27635 essential YMR094W 818 - CTCTCACAGTGATCTTCCGC R|279|T R|279|K silent|GTG>GTC|V|278 silent|GTG>GTA|V|278 0 0 0 0 1.6999543324723092 P35203 0.932735025882721 0.955805003643036 0.0 0.0 54.907660502371186 55.00000000000001 1.0 no 10400 chrXIII_456795 27638 essential YMR094W 970 + GACTAGCTGACTTTACAAGA L|325|V silent|CTA>TTA|L|325 A|326|G A|326|V 0 0 0 0 0.6480627857601244 P35203 0.9512209892272948 0.9484469890594482 0.9504740238189696 1.0 0.0 0.0 42.60512642622075 40.0 1.0 no 10401 chrXIII_484252r 27644 essential YMR108W 171 - TCAACATTGAAACTTGGAGC D|64|H D|64|N V|63|L V|63|I ILV2 IsoLeucine-plus-Valine requiring 687.0 0 1 0 0 -0.2832916350019521 P07342 0.9707800149917604 0.9937660098075868 1.0150799751281738 1.0190299749374392 40.22687678705506 40.0 1.0 no 10402 chrXIII_484333 27648 essential YMR108W 249 + GACATGGATACCTCTTTCGT D|84|E silent|GAC>GAT|D|84 ILV2 IsoLeucine-plus-Valine requiring 687.0 0 0 0 0 -0.9079099227205772 P07342 0.9768649935722352 0.2669399976730347 49.414975903778725 45.0 1.0 no 10403 chrXIII_484342 27649 essential YMR108W 258 + ACCTCTTTCGTCGGTTTAAC silent|ACC>ACG|T|87 silent|ACC>ACT|T|87 T|87|S T|87|I ILV2 IsoLeucine-plus-Valine requiring 687.0 0 0 0 0 0.1438762822347777 P07342 0.9799699783325196 0.9372339844703674 0.5350021719932556 0.10881613940000534 0.5380200147628784 -0.4033600091934204 49.38996661591978 45.0 1.0 no 10404 chrXIII_484391r 27652 essential YMR108W 310 - TACAGTATCAACGTTTTGTC V|110|L V|110|I ILV2 IsoLeucine-plus-Valine requiring 687.0 0 0 0 0 1.1287659574622286 P07342 0.912504017353058 0.9396960139274596 0.05901884660124779 0.46131432056427 -0.35199999809265137 -0.6031799912452698 41.61648542486881 35.0 1.0 no 10405 chrXIII_484408 27653 essential YMR108W 324 + ACTGTATTTGGTTATCCAGG T|109|S T|109|I ILV2 IsoLeucine-plus-Valine requiring 687.0 0 0 0 0 0.4387956884962803 P07342 0.8314269781112671 0.8216059803962708 0.3980255424976349 0.3981633484363556 1.5104000568389893 0.1813800036907196 47.33581824371601 40.0 1.0 no 10406 chrXIII_484489r 27656 essential YMR108W 408 - CCGGCACCTTGTTCGTGTTT G|143|R G|143|S A|142|P A|142|T ILV2 IsoLeucine-plus-Valine requiring 687.0 0 0 0 0 -2.1324965274758134 P07342 0.567084014415741 0.8303340077400208 0.5732560157775879 0.6213889718055725 0.024580951780080795 0.12506547570228574 0.0 0.0 18.9210205078125 3.122420072555542 3.7398600578308105 1.7731399536132812 58.204596075604975 55.00000000000001 1.0 yes 10407 chrXIII_484600r 27658 essential YMR108W 519 - TCTGCAAAGGCATCTGCCAT D|180|H D|180|N A|179|P A|179|T ILV2 IsoLeucine-plus-Valine requiring 687.0 0 0 0 0 -0.9042548192337934 P07342 0.5760250091552734 0.6420879960060121 0.6921290159225464 0.8958740234375 0.0 0.0 0.3166253864765167 0.555066704750061 3.993760108947754 -0.2711000144481659 3.6542599201202393 0.18411999940872192 52.795827369169615 50.0 1.0 no 10408 chrXIII_484627 27660 essential YMR108W 543 + ATTCCAATGGTTGTCTTTAC P|183|A P|183|S P|183|R P|183|L ILV2 IsoLeucine-plus-Valine requiring 687.0 0 0 0 0 -0.2821990333475645 P07342 0.7396669983863831 0.7038630247116089 0.575160026550293 0.5721859931945801 0.0 0.0 0.0 0.0 1.9723999500274656 2.0350000858306885 2.989520072937012 3.1582798957824707 45.02877811619294 35.0 1.0 no 10409 chrXIII_484657r 27661 essential YMR108W 576 - TCAGTACCGATAGCACTAGT D|199|H D|199|N G|197|A G|197|D ILV2 IsoLeucine-plus-Valine requiring 687.0 0 0 0 0 -0.6959035911335548 P07342 0.7778450250625609 0.9068350195884703 0.7957559823989868 0.8176860213279724 0.03709165006875992 0.19666655361652371 0.10103417187929152 0.012988050468266009 -0.4366599917411804 -0.4929400086402893 2.5116000175476074 3.146399974822998 -0.17633000016212466 -0.5982500314712524 3.1974899768829346 3.848209857940674 49.186090311663115 45.0 1.0 no 10410 chrXIII_484709 27662 essential YMR108W 625 + TTTCTAGATCTTGTACGAAA S|210|C S|210|F ILV2 IsoLeucine-plus-Valine requiring 687.0 0 0 0 0 0.7579987918272453 P07342 0.6092889904975891 0.5814340114593506 0.00945921055972576 0.004497842863202095 0.9060400128364564 1.0283199548721311 38.23370825108413 30.0 1.0 no 10411 chrXIII_484780 27663 essential YMR108W 696 + GCTTTTGAAATTGCCACGAG A|233|G A|233|V ILV2 IsoLeucine-plus-Valine requiring 687.0 0 0 0 0 -0.3103497960211339 P07342 0.8209859728813171 0.6659799814224243 0.0 0.0 1.9426000118255613 3.704740047454834 45.56659581998304 45.0 1.0 no 10412 chrXIII_485077 27669 essential YMR108W 993 + ACCACTACTTTACAAGGTTT silent|ACC>ACG|T|332 silent|ACC>ACT|T|332 T|332|S T|332|I ILV2 IsoLeucine-plus-Valine requiring 687.0 0 0 0 0 -0.4923096291737837 P07342 0.7695509791374207 0.7198079824447632 0.0710504800081253 0.013090563006699085 1.7344000339508057 1.741860032081604 44.519584446785466 35.0 1.0 no 10413 chrXIII_485119r 27671 essential YMR108W 1038 - CCAAGCATATCCAATGATTT G|353|R G|353|S M|351|I M|351|I ILV2 IsoLeucine-plus-Valine requiring 687.0 0 0 0 0 -1.2578472606545863 P07342 0.5738059878349304 0.6553760170936584 0.6818310022354126 0.6818310022354126 0.0 0.0 0.0 0.0 9.837900161743164 6.874080181121826 0.7258800268173218 0.7258800268173218 43.71895785601345 35.0 1.0 no 10414 chrXIII_485183r 27674 essential YMR108W 1102 - ACCAACTGCAATTATCAAGT G|374|R G|374|S G|374|A G|374|D ILV2 IsoLeucine-plus-Valine requiring 687.0 0 0 0 0 -2.4668981645376347 P07342 0.572160005569458 0.5903519988059998 0.5944759845733643 0.5745059847831726 0.0 0.0 0.0 0.0 14.140020370483398 7.551899909973144 5.287399768829347 12.786399841308596 42.19452662036133 35.0 1.0 yes 10415 chrXIII_485256 27676 essential YMR108W 1172 + AGCTCGTCGTGCAGCTGCCG A|392|G A|392|V R|393|G R|393|C ILV2 IsoLeucine-plus-Valine requiring 687.0 0 1 0 0 0.05841654671320672 P07342 0.7214239835739136 0.6816570162773132 0.8739129900932312 0.7419469952583313 0.02488338761031628 0.00785398855805397 0.016494115814566612 0.0022574060130864377 1.6304999589920044 3.058059930801392 2.594500064849853 2.5171399116516118 62.99434266382953 70.0 1.0 no 10416 chrXIII_485257 27677 essential YMR108W 1173 + GCTCGTCGTGCAGCTGCCGA R|393|G R|393|C A|392|G A|392|V ILV2 IsoLeucine-plus-Valine requiring 687.0 0 0 0 0 -0.6746132235603102 P07342 0.8739129900932312 0.7419469952583313 0.7214239835739136 0.6816570162773132 0.016494115814566612 0.0022574060130864377 0.02488338761031628 0.00785398855805397 2.594500064849853 2.5171399116516118 1.6304999589920044 3.058059930801392 63.99421573326043 70.0 1.0 no 10417 chrXIII_485369r 27679 essential YMR108W 1288 - TGACATCATTTTGCCCAGAT M|435|I M|435|I M|434|I M|434|I ILV2 IsoLeucine-plus-Valine requiring 687.0 0 0 0 0 -1.5797050947022742 P07342 0.9629840254783629 0.9629840254783629 0.9733489751815796 0.9733489751815796 0.34485962986946106 0.34485962986946106 0.1993091106414795 0.1993091106414795 1.7242599725723269 1.7242599725723269 1.7439600229263306 1.7439600229263306 49.097238056542274 40.0 1.0 no 10418 chrXIII_485388 27680 essential YMR108W 1304 + GTCAAAGATTTTCCCAGTTA S|436|* S|436|L ILV2 IsoLeucine-plus-Valine requiring 687.0 0 0 0 0 -0.2870786078136614 P07342 0.9416620135307312 0.2266787588596344 -0.23442000150680545 45.336110930005646 35.0 1.0 no 10419 chrXIII_485400r 27681 essential YMR108W 1319 - ATTCAGACCTCTCCTTAACT E|446|Q E|446|K ILV2 IsoLeucine-plus-Valine requiring 687.0 0 1 0 0 -0.003983834036794698 P07342 0.9455649852752686 0.9391819834709167 0.28517499566078186 0.3732641041278839 1.1957600116729736 1.4479600191116333 49.13134202776462 40.0 1.0 no 10420 chrXIII_485458r 27682 essential YMR108W 1377 - GTCTCCTCCATATAAGCGTA E|465|D silent|GAG>GAA|E|465 E|465|Q E|465|K ILV2 IsoLeucine-plus-Valine requiring 687.0 0 1 0 0 -0.07696529232619602 P07342 0.932669997215271 0.9329620003700256 0.9006189703941345 0.5977766513824463 0.5879368782043457 0.9817909002304076 3.530100107192993 3.5161800384521484 2.994119882583618 51.6978809360981 45.0 1.0 no 10421 chrXIII_485548 27688 essential YMR108W 1464 + AGACATGTCATTGTTACAAC H|490|D H|490|Y ILV2 IsoLeucine-plus-Valine requiring 687.0 0 0 0 0 -0.06598871713850962 P07342 0.9646340012550354 0.9565730094909668 0.6146496534347534 0.020854640752077103 0.1092199981212616 -0.12008000165224075 40.117093823711 35.0 1.0 no 10422 chrXIII_485553 27689 essential YMR108W 1469 + TGTCATTGTTACAACGGGTG silent|GTC>GTG|V|491 silent|GTC>GTT|V|491 ILV2 IsoLeucine-plus-Valine requiring 687.0 0 0 0 0 -0.9777274860605716 P07342 45.75012118674072 45.0 1.0 no 10423 chrXIII_485554 27690 essential YMR108W 1470 + GTCATTGTTACAACGGGTGT silent|GTC>GTG|V|491 silent|GTC>GTT|V|491 ILV2 IsoLeucine-plus-Valine requiring 687.0 0 0 0 0 0.18725455309077804 P07342 48.369024853686255 45.0 1.0 no 10424 chrXIII_485555 27691 essential YMR108W 1471 + TCATTGTTACAACGGGTGTG silent|GTC>GTG|V|491 silent|GTC>GTT|V|491 ILV2 IsoLeucine-plus-Valine requiring 687.0 0 0 0 0 -1.4026681897970703 P07342 45.75012118674061 45.0 1.0 no 10425 chrXIII_485629 27694 essential YMR108W 1545 + TTCATCACATCAGGTGGTTT F|516|L silent|TTC>TTT|F|516 I|517|M silent|ATC>ATT|I|517 ILV2 IsoLeucine-plus-Valine requiring 687.0 0 0 0 0 -0.3083731857186397 P07342 0.9097009897232056 0.9347950220108032 1.0 0.09293211996555327 1.940060019493103 1.7932599782943726 48.90245643595216 40.0 1.0 no 10426 chrXIII_494179 27695 essential YMR112C 297 - GCCTTCTTGTTGACATTGAT K|105|N silent|AAG>AAA|K|105 A|106|P A|106|T MED11 MEDiator complex 131.0 0 0 0 0 0.07706081178134197 Q99278 49.21135631550112 40.0 0.0 no 10427 chrXIII_494243r 27697 essential YMR112C 230 + ATCAACCACACAGCTACGCA S|78|* S|78|L T|79|S T|79|I MED11 MEDiator complex 131.0 0 0 0 0 -1.0339498030377807 Q99278 0.9491789937019348 0.9472420215606691 0.06372865289449693 0.8752263784408569 50.354956480395174 50.0 0.0 no 10428 chrXIII_494238 27698 essential YMR112C 238 - TATCTCCTTGCGTAGCTGTG E|85|D silent|GAG>GAA|E|85 E|85|Q E|85|K MED11 MEDiator complex 131.0 0 0 0 0 -1.5165080056183573 Q99278 53.671120046904385 50.0 0.0 no 10429 chrXIII_494344r 27699 essential YMR112C 129 + TCTCAAGTCACGTTCATATT Q|45|E Q|45|* S|44|C S|44|F MED11 MEDiator complex 131.0 0 0 0 0 0.04035167188188321 Q99278 44.12509622656825 35.0 0.0 no 10430 chrXIII_494372 27700 essential YMR112C 104 - CCTGCAACATGGAGCATAAC Q|41|H silent|CAG>CAA|Q|41 L|40|F silent|TTG>TTA|L|40 MED11 MEDiator complex 131.0 0 0 0 0 -0.1612508094527241 Q99278 46.92859905050511 50.0 0.0 no 10431 chrXIII_494373 27702 essential YMR112C 103 - CTGCAACATGGAGCATAACT L|40|F silent|TTG>TTA|L|40 M|39|I M|39|I MED11 MEDiator complex 131.0 0 0 0 0 -0.2067328790338899 Q99278 45.02902935908372 45.0 0.0 no 10432 chrXIII_495029 27703 essential YMR113W 30 + ACAAAACTACTAGAGCATTT T|11|R T|11|I L|13|V silent|CTA>TTA|L|13 0 0 0 0 0.20680725640142825 Q12676 0.6733734011650085 0.30836308002471924 0.15342512726783752 0.6741999983787537 37.010722614825454 30.0 1.0 no 10433 chrXIII_495173r 27708 essential YMR113W 177 - TCAGTAACATGCACCAAGTG D|66|H D|66|N 0 0 0 0 -0.2710644491256026 Q12676 0.006260366644710302 0.01880323700606823 45.39863188621485 45.0 1.0 no 10434 chrXIII_495198r 27709 essential YMR113W 202 - CGGCTTATTGTTGATTGTAA K|73|N silent|AAG>AAA|K|73 0 0 0 0 0.2258275524686025 Q12676 0.4354507029056549 42.993680419940866 35.0 1.0 no 10435 chrXIII_495349r 27711 essential YMR113W 353 - CTACTTCTATGACACACCAT V|124|L V|124|I E|123|Q E|123|K 0 0 0 0 -0.8308984806166559 Q12676 0.03928907588124275 0.06473138183355331 0.0 0.0 45.577633704705704 40.0 1.0 no 10436 chrXIII_495373r 27713 essential YMR113W 377 - TCGCATCAAGTCTTCCGCCA A|132|P A|132|T silent|GCG>GCC|A|132 silent|GCG>GCA|A|132 0 0 0 0 -1.3270136475323056 Q12676 0.019964560866355896 0.020222095772624016 -0.0031999999191612005 3.03439998626709 57.16212716879693 55.00000000000001 1.0 no 10437 chrXIII_495477r 27716 essential YMR113W 481 - CTCTTTAGAGATTTCAGACA E|167|Q E|167|K 0 0 0 0 0.3257459614454457 Q12676 0.17890247702598572 0.09318313747644424 42.03917668165485 35.0 1.0 no 10438 chrXIII_495524 27717 essential YMR113W 525 + GTACCCTTCACAGTGATTGA P|177|A P|177|S P|177|R P|177|L 0 0 0 0 -0.5025062744129507 Q12676 0.1305350512266159 0.10099441558122636 0.36752715706825256 0.06072298809885979 50.88734927913055 45.0 1.0 no 10439 chrXIII_495527r 27718 essential YMR113W 531 - GTTCCATCAATCACTGTGAA G|183|A G|183|E G|183|R G|183|R 0 0 0 0 0.2641295955409844 Q12676 0.1132555976510048 0.04163679480552673 0.17423610389232635 0.17423610389232635 45.68477400824463 40.0 1.0 no 10440 chrXIII_495651r 27719 essential YMR113W 655 - GTCAAAACAACCCCAGGAGT D|225|H D|225|N 0 0 0 0 -0.30859884432074364 Q12676 0.14074158668518064 0.6950631737709045 48.875071772287704 50.0 1.0 no 10441 chrXIII_495686r 27720 essential YMR113W 690 - ATCTGATATTCTCCATTCAG Q|236|H silent|CAG>CAA|Q|236 0 0 0 0 0.2076361989670417 Q12676 0.0 44.48177963588029 35.0 1.0 no 10442 chrXIII_495774r 27722 essential YMR113W 778 - TCTCGTACTTACTTCATTCT silent|ACG>ACC|T|265 silent|ACG>ACA|T|265 R|266|T R|266|K 0 0 0 0 -0.3103622446575497 Q12676 0.03762903064489365 0.08076345920562744 -11.107999801635742 -5.598199844360352 46.174600598772315 35.0 1.0 no 10443 chrXIII_495815r 27724 essential YMR113W 819 - TCCATACGATATAACCTTCC M|279|I M|279|I D|280|H D|280|N 0 0 0 0 0.9587584229750014 Q12676 0.8097244501113892 0.8097244501113892 0.14554905891418454 0.4846801161766052 0.8046000003814697 0.8046000003814697 -0.7888000011444092 -1.2710000276565552 46.13977032740633 40.0 1.0 no 10444 chrXIII_495891r 27726 essential YMR113W 895 - TACTGCAGCTGAGCCATTGT V|305|L V|305|I A|304|P A|304|T 0 0 0 0 -0.8009230069516795 Q12676 0.538111686706543 0.3770223557949066 0.0 0.0 -1.6959999799728394 -0.9100000262260436 7.611400127410889 3.0485999584198 54.61901420042785 50.0 1.0 no 10445 chrXIII_495892r 27727 essential YMR113W 896 - CTACTGCAGCTGAGCCATTG V|305|L V|305|I A|304|P A|304|T 0 0 0 0 0.014734368126971598 Q12676 0.538111686706543 0.3770223557949066 0.0 0.0 -1.6959999799728394 -0.9100000262260436 7.611400127410889 3.0485999584198 53.682056597939216 55.00000000000001 1.0 no 10446 chrXIII_495949 27728 essential YMR113W 950 + CCAGCCTTTGACCTTTGTGA Q|318|E Q|318|* P|319|A P|319|S 0 0 0 0 -1.0316957737593155 Q12676 1.0 0.8169746398925781 0.9057409763336182 55.709991036952715 50.0 1.0 no 10447 chrXIII_501443 27731 essential YMR117C 429 - GCACTTTGTTCTTCCAGCTC S|149|T S|149|N A|150|P A|150|T SPC24 Spindle Pole Component 213.0 0 1 0 0 -0.22887851828099115 Q04477 0.9512869715690612 0.9536849856376648 0.9573720097541808 0.9523990154266356 0.5137524604797363 0.2171141356229782 0.03386067971587181 0.05813172087073326 56.57406178356104 50.0 0.0 no 10448 chrXIII_501696r 27734 essential YMR117C 173 + GTCGAACAAGAAATTGAATG S|59|W S|59|L N|60|K silent|AAC>AAT|N|60 SPC24 Spindle Pole Component 213.0 0 0 0 0 1.121755091432139 Q04477 0.9288619756698608 0.9298099875450134 0.9439849853515624 0.03477305546402931 0.9843480587005616 0.9074360132217408 33.51186909949013 35.0 0.0 no 10449 chrXIII_501852 27735 essential YMR117C 20 - ATTCAACCGGATTGTCGAGT E|13|Q E|13|K V|12|L V|12|I SPC24 Spindle Pole Component 213.0 0 0 0 0 0.3251697967959258 Q04477 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.29959070682525635 0.4083447456359863 0.2007872760295868 0.1870011240243912 48.01369012790343 45.0 0.0 no 10450 chrXIII_501781 27736 essential YMR117C 91 - ATCGTGTCGGATTCTTTTCA D|37|H D|37|N SPC24 Spindle Pole Component 213.0 0 0 0 0 -1.2357219325878273 Q04477 0.9486550092697144 0.956179976463318 0.18811948597431186 0.9382714033126832 48.557883161416036 40.0 0.0 no 10451 chrXIII_523740r 27737 essential YMR128W 47 - GTTCTTTTAATTTGGCCATA E|22|Q E|22|K ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 0.5639971223003786 Q04217 44.68269909200808 30.0 1.0 no 10452 chrXIII_523888r 27741 essential YMR128W 195 - TTCTTTTCTTCTTCAGTGAG K|71|N silent|AAG>AAA|K|71 ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 0.25140510984583875 Q04217 45.456531918953495 35.0 1.0 no 10453 chrXIII_523945r 27743 essential YMR128W 252 - CTCGAAACTTTCGATTCCTT silent|TCG>TCC|S|90 silent|TCG>TCA|S|90 ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 -0.3696076996872415 Q04217 44.781095648869716 40.0 1.0 no 10454 chrXIII_524079 27744 essential YMR128W 383 + AAGCTCTAAAAGGTTAGGAG S|129|R silent|AGC>AGT|S|129 S|130|C S|130|F ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 -0.4132140875673717 Q04217 39.38371334452893 40.0 1.0 no 10455 chrXIII_524290r 27750 essential YMR128W 597 - TCCTCATTGTCCGTTGGTTT E|205|D silent|GAG>GAA|E|205 E|206|Q E|206|K ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 -0.30043533781544185 Q04217 55.67291653660897 45.0 1.0 no 10456 chrXIII_524296r 27751 essential YMR128W 603 - TTCTTCTCCTCATTGTCCGT K|207|N silent|AAG>AAA|K|207 E|206|D silent|GAG>GAA|E|206 ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 -0.06019104219652061 Q04217 56.349503560914286 45.0 1.0 no 10457 chrXIII_524335 27752 essential YMR128W 639 + GATCATAGACCAGCAAAATT H|215|D H|215|Y ECM16 ExtraCellular Mutant 1267.0 0 1 0 0 -0.019607657518840776 Q04217 40.051363728247736 35.0 1.0 no 10458 chrXIII_524344r 27754 essential YMR128W 651 - CCAGATCCACCAAATTTTGC G|224|R G|224|S G|222|A G|222|E ECM16 ExtraCellular Mutant 1267.0 0 1 0 0 0.41152134220617803 Q04217 48.464458567635404 45.0 1.0 no 10459 chrXIII_524572r 27756 essential YMR128W 879 - GCGCTTTCAACTTCTTCGAG S|299|T S|299|N A|300|P A|300|T ECM16 ExtraCellular Mutant 1267.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.16406672051624255 Q04217 49.864492584696166 50.0 1.0 no 10460 chrXIII_524571r 27757 essential YMR128W 878 - CGCTTTCAACTTCTTCGAGT S|299|T S|299|N E|298|Q E|298|K ECM16 ExtraCellular Mutant 1267.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.0612314801796354 Q04217 48.79161982195251 45.0 1.0 no 10461 chrXIII_524625r 27758 essential YMR128W 932 - ATTCGTTAGCAACATCATTT E|317|Q E|317|K ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 0.5597437586227728 Q04217 42.006951035848715 30.0 1.0 no 10462 chrXIII_524637 27760 essential YMR128W 941 + TGCTAACGAATTCAAGGATT A|315|G A|315|V N|316|K silent|AAC>AAT|N|316 ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 -0.22462710863788787 Q04217 39.37003927081389 35.0 1.0 no 10463 chrXIII_524804r 27762 essential YMR128W 1111 - TTCAACATAGAAGGCTTTAC E|377|Q E|377|K V|376|L V|376|I ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 0.6936540453788818 Q04217 39.567983342207754 35.0 1.0 no 10464 chrXIII_524805r 27763 essential YMR128W 1112 - CTTCAACATAGAAGGCTTTA E|377|Q E|377|K V|376|L V|376|I ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 0.005788056224120014 Q04217 40.948443717308066 35.0 1.0 no 10465 chrXIII_524813r 27764 essential YMR128W 1120 - TCTGCTAACTTCAACATAGA R|380|T R|380|K S|379|T S|379|N ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 0.31835760501269594 Q04217 41.20015334393696 35.0 1.0 no 10466 chrXIII_524964 27765 essential YMR128W 1268 + AGTCCCACAATTTTTATATG silent|GTC>GTG|V|424 silent|GTC>GTT|V|424 P|425|A P|425|S ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 -0.38380214442474425 Q04217 41.99515261798422 30.0 1.0 no 10467 chrXIII_524969 27767 essential YMR128W 1273 + CACAATTTTTATATGAGGCT Q|426|E Q|426|* ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 -0.08264048136810145 Q04217 39.882177525965794 30.0 1.0 no 10468 chrXIII_525010r 27770 essential YMR128W 1317 - CCCACCATTCCTGGGTAATC silent|GTG>GTC|V|445 silent|GTG>GTA|V|445 G|446|R G|446|S ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 -0.8470668909964317 Q04217 56.41821309936682 55.00000000000001 1.0 no 10469 chrXIII_525043r 27771 essential YMR128W 1350 - GACACAGCGGCCACTCTTCT silent|GTG>GTC|V|456 silent|GTG>GTA|V|456 V|456|L V|456|M ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 1.14084455220001 Q04217 58.21720394328088 60.0 1.0 no 10470 chrXIII_525082 27776 essential YMR128W 1386 + GCTAATGAATTGGGGGACCA A|463|G A|463|V ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 -0.7091723415886103 Q04217 48.699070564224776 50.0 1.0 no 10471 chrXIII_525227r 27777 essential YMR128W 1534 - TGCTTCATCTATGATAATGG A|518|P A|518|T E|517|Q E|517|K ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 -2.7415671037598535 Q04217 40.980115053180214 35.0 1.0 yes 10472 chrXIII_525294r 27778 essential YMR128W 1601 - TAGCTCTTAACCGAACACAA A|540|P A|540|T R|539|T R|539|K ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 -1.2651444676160395 Q04217 42.59919822900463 40.0 1.0 no 10473 chrXIII_525362 27779 essential YMR128W 1666 + TCATCATGTCAGCTACATTA I|556|M silent|ATC>ATT|I|556 I|557|M silent|ATC>ATT|I|557 ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 0.3672520132227438 Q04217 45.10518484518264 35.0 1.0 no 10474 chrXIII_525537r 27784 essential YMR128W 1844 - TAGCGCCAGGAGGAAGTTTC A|621|P A|621|T G|620|A G|620|D ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 -4.671752844158619 Q04217 52.423748455900466 55.00000000000001 1.0 yes 10475 chrXIII_525543 27785 essential YMR128W 1847 + ACTTCCTCCTGGCGCTATAT L|617|V L|617|F P|618|A P|618|S ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 0.2033627504835893 Q04217 56.549399866651925 50.0 1.0 no 10476 chrXIII_525641r 27788 essential YMR128W 1948 - TTCTAAATCTTTGTTGTACT E|656|Q E|656|K ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 0.4067550436764903 Q04217 38.78302784553483 25.0 1.0 no 10477 chrXIII_525690 27789 essential YMR128W 1994 + TTCAAAAACAACAGATTTGG S|666|* S|666|L ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 -0.9410803139735424 Q04217 33.16809777422464 30.0 1.0 no 10478 chrXIII_525849r 27791 essential YMR128W 2156 - TAGCTGTTTGCCCTTCAGTT A|725|P A|725|T ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 0.8159614753702698 Q04217 56.60039215306887 45.0 1.0 no 10479 chrXIII_525910r 27793 essential YMR128W 2217 - ACTCTCATTTGTTCCTTGGT R|745|T R|745|K V|746|L V|746|I ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 0.217815903757142 Q04217 52.37316493268713 40.0 1.0 no 10480 chrXIII_525931 27794 essential YMR128W 2235 + GTCTTTCAAAAACCTCCTCA silent|GTC>GTG|V|746 silent|GTC>GTT|V|746 Q|748|E Q|748|* ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 0.1024871437421202 Q04217 46.265393769046106 40.0 1.0 no 10481 chrXIII_525946r 27795 essential YMR128W 2253 - ATACAAAGCCTAGAACCTTG C|757|S C|757|Y ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 -1.7319822446865452 Q04217 42.49333466016759 40.0 1.0 no 10482 chrXIII_526006r 27796 essential YMR128W 2313 - TCAACAACATATCTAACTCC D|778|H D|778|N V|777|L V|777|I ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 -4.715354211108897 Q04217 39.51118579910821 35.0 1.0 yes 10483 chrXIII_526112r 27801 essential YMR128W 2419 - TGCTCTACCGCTTCTTTGAT A|813|P A|813|T R|812|T R|812|K ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 -0.802044261524328 Q04217 52.783186142908 45.0 1.0 no 10484 chrXIII_526325r 27807 essential YMR128W 2632 - TTGCAGTAATTGTATTGCCT silent|CTG>CTC|L|883 silent|CTG>CTA|L|883 ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 -0.47255229737381704 Q04217 46.79076523339803 35.0 1.0 no 10485 chrXIII_526333 27808 essential YMR128W 2637 + ATACAATTACTGCAATATTT Q|881|E Q|881|* ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 0.6452352622682873 Q04217 34.713310817930676 20.0 1.0 no 10486 chrXIII_526479 27812 essential YMR128W 2783 + AGCAATTGTTAGTGCCCTTT A|929|G A|929|V ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 0.131341454465378 Q04217 51.6161270420684 40.0 1.0 no 10487 chrXIII_526510r 27813 essential YMR128W 2817 - AACTCAAATTCATTGATAAA E|945|D silent|GAG>GAA|E|945 E|945|Q E|945|K ECM16 ExtraCellular Mutant 1267.0 0 0 0 0 1.7920409913123403 Q04217 30.993282215881486 20.0 1.0 no 10488 chrXIII_533673 27815 essential YMR131C 1006 - ACATCCTGCGGTTGCAAAAA C|342|S C|342|Y G|341|A G|341|E RRB1 Regulator of Ribosome Biogenesis 511.0 0 0 0 0 -0.4125803756543208 Q04225 0.8952558636665344 0.027665575966238976 0.3248724639415741 0.024588340893387798 46.34799380320635 45.0 0.0 no 10489 chrXIII_533677r 27816 essential YMR131C 999 + TCCACCGTTTTTGCAACCGC silent|TCC>TCG|S|334 silent|TCC>TCT|S|334 S|334|C S|334|F RRB1 Regulator of Ribosome Biogenesis 511.0 0 0 0 1 0.8223028189649013 Q04225 0.0550847202539444 0.058195855468511574 55.90252137268698 55.00000000000001 0.0 no 10490 chrXIII_533771 27819 essential YMR131C 908 - CCCATCTCGATGTGTGCCTT W|309|S W|309|* W|309|C W|309|* RRB1 Regulator of Ribosome Biogenesis 511.0 0 0 0 0 0.13134173555382028 Q04225 0.4091120362281799 0.1772521585226059 58.76682946010532 55.00000000000001 0.0 no 10491 chrXIII_533772 27820 essential YMR131C 907 - CCATCTCGATGTGTGCCTTT W|309|S W|309|* R|308|T R|308|K RRB1 Regulator of Ribosome Biogenesis 511.0 0 0 0 0 -1.9393787748276183 Q04225 0.4091120362281799 0.052049219608306885 0.26536476612091064 55.46333832450245 50.0 0.0 no 10492 chrXIII_533772r 27822 essential YMR131C 904 + CCCAAAGGCACACATCGAGA Q|303|E Q|303|* silent|ACC>ACG|T|302 silent|ACC>ACT|T|302 RRB1 Regulator of Ribosome Biogenesis 511.0 0 0 0 0 -0.4769388292180996 Q04225 0.4419863522052765 50.199559005518104 55.00000000000001 0.0 no 10493 chrXIII_533883r 27823 essential YMR131C 793 + TTCACACTGTAAAAAATCAT H|266|D H|266|Y H|266|Q silent|CAC>CAT|H|266 RRB1 Regulator of Ribosome Biogenesis 511.0 0 0 0 0 0.2389322437030511 Q04225 0.1925230175256729 1.0 0.2748267650604248 33.427312671195466 25.0 0.0 no 10494 chrXIII_533938r 27825 essential YMR131C 738 + AGCAAAGCTTTTTCCACACC S|247|R silent|AGC>AGT|S|247 RRB1 Regulator of Ribosome Biogenesis 511.0 0 0 0 0 0.9721110156416036 Q04225 0.14191316068172455 49.815457640418636 45.0 0.0 no 10495 chrXIII_534015 27828 essential YMR131C 664 - TAACACCTCTTGATTAGAAA silent|GTG>GTC|V|227 silent|GTG>GTA|V|227 V|227|L V|227|M RRB1 Regulator of Ribosome Biogenesis 511.0 0 0 0 0 1.1511515685368414 Q04225 0.6565854549407959 0.2236993908882141 37.64560971512736 30.0 0.0 no 10496 chrXIII_534216r 27830 essential YMR131C 460 + CCACGGCTACTCAATCTTCC T|155|R T|155|M silent|ACC>ACG|T|154 silent|ACC>ACT|T|154 RRB1 Regulator of Ribosome Biogenesis 511.0 0 0 0 0 0.2091656927112732 Q04225 0.024865077808499336 0.014003762044012548 53.93754002947645 55.00000000000001 0.0 no 10497 chrXIII_534298 27831 essential YMR131C 381 - TCTAATGTCAAGCATGGCCA D|134|H D|134|N RRB1 Regulator of Ribosome Biogenesis 511.0 0 0 0 0 -4.901861885068904 Q04225 0.005146149080246687 0.021175231784582138 49.41516490867088 45.0 0.0 yes 10498 chrXIII_534315r 27832 essential YMR131C 361 + TACATAATGTCAATATGCCA H|122|D H|122|Y RRB1 Regulator of Ribosome Biogenesis 511.0 0 0 0 0 -0.5741406461121568 Q04225 0.0 0.0 40.098007209433604 30.0 0.0 no 10499 chrXIII_534347 27833 essential YMR131C 332 - AAACAGTGGGATCAGCCTCA V|117|L V|117|I RRB1 Regulator of Ribosome Biogenesis 511.0 0 0 0 0 -0.6107336543264092 Q04225 0.1039482280611992 0.15108022093772888 50.46277611900348 50.0 0.0 no 10500 chrXIII_534381r 27834 essential YMR131C 295 + CCCATATGTCTCGTCCATTA H|100|D H|100|Y silent|CCC>CCG|P|99 silent|CCC>CCT|P|99 RRB1 Regulator of Ribosome Biogenesis 511.0 0 0 0 0 0.10608378918723137 Q04225 0.3274683356285095 0.09389603137969972 53.45290301012949 45.0 0.0 no 10501 chrXIII_534425 27836 essential YMR131C 254 - TTTCTTTGTTGCCTTCGGAT E|91|Q E|91|K RRB1 Regulator of Ribosome Biogenesis 511.0 0 0 0 0 -0.32633800173680144 Q04225 0.5318324565887451 0.7284262776374817 51.39423647444994 40.0 0.0 no 10502 chrXIII_534420 27837 essential YMR131C 259 - GATCTTTTCTTTGTTGCCTT K|92|N silent|AAG>AAA|K|92 RRB1 Regulator of Ribosome Biogenesis 511.0 0 0 0 0 0.4072879871169821 Q04225 0.4963325262069702 50.0834074237045 35.0 0.0 no 10503 chrXIII_534436r 27838 essential YMR131C 240 + GTACAAAAGGACCAATCCGA Q|82|E Q|82|* RRB1 Regulator of Ribosome Biogenesis 511.0 0 0 0 0 0.6304967812294944 Q04225 1.0 43.54577301386695 45.0 0.0 no 10504 chrXIII_534470 27839 essential YMR131C 209 - CTTCTTCTTGCTTTTTCCTA E|76|Q E|76|K E|75|Q E|75|K RRB1 Regulator of Ribosome Biogenesis 511.0 0 0 0 0 0.7013279237372876 Q04225 0.3755351006984711 0.5157790780067444 0.3412113785743713 0.4049809277057648 50.476200195027104 35.0 0.0 no 10505 chrXIII_534591 27842 essential YMR131C 88 - AGCATCTTGCTCTTCAGAGG A|36|P A|36|T D|35|H D|35|N RRB1 Regulator of Ribosome Biogenesis 511.0 0 0 0 0 0.6794986339827802 Q04225 0.2728637754917145 0.575950562953949 0.03695112094283104 0.1782570779323578 52.604285457052576 50.0 0.0 no 10506 chrXIII_537921r 27847 essential YMR134W 86 - TCCTACCACTTATTCGATCA R|35|T R|35|K R|35|S silent|AGG>AGA|R|35 ERG29 ERGosterol biosynthesis 237.0 0 0 0 0 0.5617721291838927 P40207 48.77676867596836 40.0 1.0 no 10507 chrXIII_537946 27849 essential YMR134W 108 + ACTCTCTTTTTGATAGTGGT L|38|V L|38|F T|37|S T|37|I ERG29 ERGosterol biosynthesis 237.0 0 0 0 0 0.5042116005430208 P40207 46.47944569844469 35.0 1.0 no 10508 chrXIII_538183r 27851 essential YMR134W 348 - TCCAATTCTGATACAAACAC L|122|F silent|TTG>TTA|L|122 D|123|H D|123|N ERG29 ERGosterol biosynthesis 237.0 0 0 0 0 0.7929315008428159 P40207 0.019459903240203857 0.2109130024909973 1.0 38.876710634189074 35.0 1.0 no 10509 chrXIII_538251r 27853 essential YMR134W 416 - ATTCAACATGAAATTTTAAT E|145|Q E|145|K V|144|L V|144|I ERG29 ERGosterol biosynthesis 237.0 0 0 0 0 -0.3584510365992357 P40207 0.0 0.0 0.8389151096343994 1.0 30.15129022770884 15.0 1.0 no 10510 chrXIII_538306r 27854 essential YMR134W 471 - CGCAAGGTAGTACCAAACTC L|163|F silent|TTG>TTA|L|163 ERG29 ERGosterol biosynthesis 237.0 0 0 0 0 -3.0380204635827885 P40207 0.012629587203264236 46.087307305580396 50.0 1.0 yes 10511 chrXIII_538316 27855 essential YMR134W 478 + GTACTACCTTGCGTGTATTG T|161|S T|161|I T|162|S T|162|I ERG29 ERGosterol biosynthesis 237.0 0 0 0 0 0.4150453796379053 P40207 0.5169256925582886 0.0270660761743784 0.4989872872829437 0.038724318146705634 48.975843963845136 45.0 1.0 no 10512 chrXIII_538322r 27856 essential YMR134W 487 - TCTCAGCCTCAATACACGCA silent|CTG>CTC|L|168 silent|CTG>CTA|L|168 R|169|T R|169|K ERG29 ERGosterol biosynthesis 237.0 0 0 0 0 -0.1342129311089406 P40207 0.012222618795931341 1.0 52.12982000236075 50.0 1.0 no 10513 chrXIII_538250r 27857 essential YMR134W 415 - TTCAACATGAAATTTTAATG E|145|Q E|145|K V|144|L V|144|I ERG29 ERGosterol biosynthesis 237.0 0 0 0 0 0.06841533742081107 P40207 0.0 0.0 0.8389151096343994 1.0 30.210158932601253 20.0 1.0 no 10514 chrXIII_557931 27860 essential YMR146C 574 - GGACTTTTCGTGCAAATCGA K|197|N silent|AAG>AAA|K|197 TIF34 Translation Initiation Factor 347.0 0 0 0 0 -1.3669301666368197 P40217 0.9355990290641784 0.4990290105342865 0.1628199964761734 45.86679196717989 45.0 0.0 no 10515 chrXIII_558001r 27861 essential YMR146C 501 + ATCATTGCAGGCCATAAAGA I|168|M silent|ATC>ATT|I|168 TIF34 Translation Initiation Factor 347.0 0 0 0 0 -0.5653087258254648 P40217 0.9598389863967896 0.005194444674998522 0.5938000082969666 45.63275600286704 40.0 0.0 no 10516 chrXIII_558148 27864 essential YMR146C 357 - TCGTATATGTTAATGGAACC E|126|Q E|126|K TIF34 Translation Initiation Factor 347.0 0 0 0 0 0.03820487647533205 P40217 0.956179976463318 0.9475290179252625 0.07245230674743652 0.17998728156089785 0.22453999519348145 0.09173999726772307 40.1431423793349 35.0 0.0 no 10517 chrXIII_558141 27866 essential YMR146C 364 - TTCAATTTCGTATATGTTAA E|128|Q E|128|K TIF34 Translation Initiation Factor 347.0 0 0 0 0 0.3813093681707584 P40217 0.956179976463318 0.9475290179252625 0.431953102350235 1.0 -0.6273400187492371 -0.7042400240898132 35.240309962063634 20.0 0.0 no 10518 chrXIII_558188r 27867 essential YMR146C 314 + TAACTACTTTCTAGCTATCT N|106|K silent|AAC>AAT|N|106 Y|107|* silent|TAC>TAT|Y|107 TIF34 Translation Initiation Factor 347.0 0 0 0 0 -0.00616662011650064 P40217 0.9439849853515624 1.0 0.07890000194311142 41.52357294536257 30.0 0.0 no 10519 chrXIII_558312 27871 essential YMR146C 193 - ACTTCCTGTAACACAGTACT S|71|T S|71|N G|70|A G|70|E TIF34 Translation Initiation Factor 347.0 0 0 0 0 -1.2219181024221268 P40217 0.9512869715690612 0.9536849856376648 0.9499930143356324 0.9438679814338684 0.0428476631641388 0.0181544590741396 0.23378583788871765 0.0039856708608567715 5.002779960632324 6.227620124816895 1.6018600463867188 10.469019889831543 46.71774505342199 40.0 0.0 no 10520 chrXIII_558316r 27872 essential YMR146C 186 + TTCACCAAGTACTGTGTTAC F|63|L silent|TTC>TTT|F|63 T|64|S T|64|I TIF34 Translation Initiation Factor 347.0 0 0 0 0 -0.4295781944637975 P40217 0.9387490153312684 0.9491789937019348 0.9472420215606691 0.21952204406261444 1.0 0.014024434611201286 1.2935400009155271 0.751800000667572 1.2254400253295898 1.330940008163452 45.39284972894552 40.0 0.0 no 10521 chrXIII_558388r 27874 essential YMR146C 114 + TCGTTGAACGGTGAAAGATT S|39|W S|39|L TIF34 Translation Initiation Factor 347.0 0 0 0 0 -0.2432470068126523 P40217 0.9288619756698608 0.9298099875450134 0.00129731313791126 0.007125807926058768 6.586599826812744 2.681220054626465 40.562267953082774 40.0 0.0 no 10522 chrXIII_558402 27875 essential YMR146C 103 - GTTCAACGAATACCAAACAC L|40|F silent|TTG>TTA|L|40 silent|TCG>TCC|S|39 silent|TCG>TCA|S|39 TIF34 Translation Initiation Factor 347.0 0 0 0 0 -5.479712415650377 P40217 0.9587849974632264 0.5319169163703918 0.3996999859809876 0.4416399896144867 39.07567926915482 40.0 0.0 yes 10523 chrXIII_561004 27876 essential YMR149W 8 + CTTCAAAACACTTGCGGCCT F|4|L silent|TTC>TTT|F|4 SWP1 Suppressor of a WbP1 mutation 286.0 0 0 0 0 -0.04059190365596513 Q02795 0.9677240252494812 1.0 49.41644916514521 50.0 1.0 no 10524 chrXIII_561084r 27880 essential YMR149W 91 - CCTAGACTTTCCTGCGGTGG R|37|T R|37|K K|35|N silent|AAG>AAA|K|35 SWP1 Suppressor of a WbP1 mutation 286.0 0 0 0 0 -0.8026321508622232 Q02795 0.9510110020637512 0.969380021095276 0.915198028087616 0.5986520051956177 0.9144718050956726 0.17973633110523224 57.07414875310985 60.0 1.0 no 10525 chrXIII_561178r 27883 essential YMR149W 185 - TTACTTGAATCACCTCGTTA V|68|L V|68|I SWP1 Suppressor of a WbP1 mutation 286.0 0 0 0 0 0.7448870186949685 Q02795 0.9693499803543092 0.9770190119743348 1.0 0.3624078035354614 44.004862333928536 35.0 1.0 no 10526 chrXIII_561227r 27884 essential YMR149W 234 - ATCAATAAGGTGTTCTGGAA L|84|F silent|TTG>TTA|L|84 SWP1 Suppressor of a WbP1 mutation 286.0 0 0 0 0 0.5727481656421858 Q02795 0.9798439741134644 0.053160157054662704 40.55330074158695 35.0 1.0 no 10527 chrXIII_561228r 27885 essential YMR149W 235 - TATCAATAAGGTGTTCTGGA L|84|F silent|TTG>TTA|L|84 SWP1 Suppressor of a WbP1 mutation 286.0 0 0 0 0 0.036266779836813035 Q02795 0.9798439741134644 0.053160157054662704 41.44468652843335 35.0 1.0 no 10528 chrXIII_561256 27886 essential YMR149W 260 + ACCTAATAAGAACCTAGAAA P|88|R P|88|L P|88|A P|88|S SWP1 Suppressor of a WbP1 mutation 286.0 0 0 0 0 0.1234629740918963 Q02795 0.95032000541687 0.9589239954948424 0.9763929843902588 0.9679129719734192 0.04971807077527046 0.16706997156143188 0.33276692032814026 0.14708192646503448 35.862607270286844 30.0 1.0 no 10529 chrXIII_561277 27888 essential YMR149W 281 + GGCTTTTGAACCCGAAATTA A|95|G A|95|V SWP1 Suppressor of a WbP1 mutation 286.0 0 0 0 0 -0.9814938845403622 Q02795 0.9672009944915771 0.9664270281791688 0.16888996958732605 1.0 44.76749511641066 40.0 1.0 no 10530 chrXIII_561287r 27889 essential YMR149W 294 - TTGCCATTGTCCTTAATTTC G|104|A G|104|D G|104|R G|104|S SWP1 Suppressor of a WbP1 mutation 286.0 0 0 0 0 0.816460141289927 Q02795 0.9656509757041932 0.9535760283470154 0.9477360248565674 0.9668909907341005 0.5292840600013733 0.7196466326713562 0.3497057557106018 0.4982219636440277 47.436427711572726 35.0 1.0 no 10531 chrXIII_561315r 27890 essential YMR149W 322 - ATCTATCCTGTATTTATACA D|114|H D|114|N R|112|S silent|AGG>AGA|R|112 SWP1 Suppressor of a WbP1 mutation 286.0 0 0 0 0 -0.6002842432741486 Q02795 0.965224027633667 0.97645902633667 0.9386019706726074 0.14925581216812134 0.5006268024444579 0.7867985963821411 41.103402152928254 25.0 1.0 no 10532 chrXIII_561415 27893 essential YMR149W 419 + GTCATCTACCGCCAAACCAA S|141|* S|141|L S|142|C S|142|F SWP1 Suppressor of a WbP1 mutation 286.0 0 0 0 0 -0.6125389973912989 Q02795 0.9508730173110962 0.9554020166397096 0.9325379729270936 0.1480773687362671 0.039038851857185364 0.040440622717142105 50.914897545068406 50.0 1.0 no 10533 chrXIII_597905 27897 essential YMR168C 1234 - ATACATCTTAAACAATTTCC M|417|I M|417|I K|416|N silent|AAG>AAA|K|416 CEP3 CEntromere Protein 608.0 0 0 0 0 -0.05759941323735303 P40969 0.9553959965705872 0.9553959965705872 0.9355990290641784 0.2527563571929932 0.2527563571929932 0.1988806128501892 2.603199958801269 2.603199958801269 4.001599788665772 35.94499929348473 25.0 0.0 no 10534 chrXIII_597923r 27898 essential YMR168C 1213 + TTCAAATATCTACTGTTTCC Q|406|E Q|406|* CEP3 CEntromere Protein 608.0 0 0 0 0 0.3153070446900192 P40969 0.9590039849281312 0.015900690108537674 0.8673999905586243 40.50610436055399 30.0 0.0 no 10535 chrXIII_598177r 27903 essential YMR168C 959 + ACAACATGCAGCATATTTGC Q|321|E Q|321|* H|322|D H|322|Y CEP3 CEntromere Protein 608.0 0 0 0 0 0.8862223531875976 P40969 0.9590039849281312 0.9473130106925964 0.9489949941635132 0.9259097576141356 0.07059774547815323 0.012468695640563965 -0.0272000003606081 44.80876043141257 40.0 0.0 no 10536 chrXIII_598290r 27906 essential YMR168C 846 + AGCATCGCTAAAGTAACCTT S|283|R silent|AGC>AGT|S|283 I|284|M silent|ATC>ATT|I|284 CEP3 CEntromere Protein 608.0 0 0 0 0 0.2309318374892199 P40969 0.9417110085487366 0.9598389863967896 0.6359490156173706 0.07658657431602478 0.7400000095367432 -0.626800000667572 -0.6565999984741211 45.18119100171111 40.0 0.0 no 10537 chrXIII_598298 27908 essential YMR168C 841 - TACTTTAGCGATGCTTTCAA V|287|L V|287|I CEP3 CEntromere Protein 608.0 0 0 0 0 0.2671693867015668 P40969 0.9539830088615416 0.9574310183525084 0.8011409044265747 0.6670849919319153 -0.9563999772071838 -0.7716000080108643 43.83045913891885 35.0 0.0 no 10538 chrXIII_598401 27911 essential YMR168C 738 - GCCAACAACGGTTCATCGTA L|252|F silent|TTG>TTA|L|252 A|253|P A|253|T CEP3 CEntromere Protein 608.0 0 0 0 0 -0.5707102276376166 P40969 0.9587849974632264 0.9573720097541808 0.9523990154266356 0.1311192363500595 0.03628791123628616 0.0450068898499012 0.11919999867677687 5.797800064086914 1.8475999832153318 -0.04720000177621842 49.680468909371434 50.0 0.0 no 10539 chrXIII_598402 27912 essential YMR168C 737 - CCAACAACGGTTCATCGTAG L|252|F silent|TTG>TTA|L|252 L|251|F silent|TTG>TTA|L|251 CEP3 CEntromere Protein 608.0 0 0 0 0 -0.3600724635043731 P40969 0.9587849974632264 0.9587849974632264 0.1311192363500595 0.4239489138126373 0.11919999867677687 -0.369599997997284 -0.04720000177621842 1.5310000181198118 46.34711685388857 50.0 0.0 no 10540 chrXIII_598452 27914 essential YMR168C 687 - GCTTGAACGAGCCTTATATC A|236|P A|236|T CEP3 CEntromere Protein 608.0 0 0 0 0 -1.2906166232245324 P40969 0.9573720097541808 0.9523990154266356 0.08848906308412552 0.4254217743873596 5.287799835205078 0.4490000009536743 46.9696748513013 45.0 0.0 no 10541 chrXIII_598463r 27916 essential YMR168C 673 + TCATGGCGCATCCCGATATA F|225|L silent|TTC>TTT|F|225 A|227|G A|227|V CEP3 CEntromere Protein 608.0 0 0 0 0 0.2302110469835135 P40969 0.9387490153312684 0.9484469890594482 0.9504740238189696 0.0 0.35729822516441345 0.2059648483991623 1.465999960899353 0.2266000062227249 1.0504000186920166 1.2776000499725342 0.8432000279426575 1.3896000385284424 53.044625954876096 50.0 0.0 no 10542 chrXIII_598741r 27921 essential YMR168C 395 + TATCAGTGAATTATATTTGA I|133|M silent|ATC>ATT|I|133 CEP3 CEntromere Protein 608.0 0 0 0 0 0.012704007760645614 P40969 0.9598389863967896 0.017704414203763008 -3.0381999015808105 33.92430437927641 20.0 0.0 no 10543 chrXIII_598776r 27923 essential YMR168C 360 + AACTTAGGTGCTTTGTATTT N|121|K silent|AAC>AAT|N|121 CEP3 CEntromere Protein 608.0 0 0 0 0 -0.4515270430241389 P40969 0.9439849853515624 1.0 1.4509999752044678 43.05083808935689 30.0 0.0 no 10544 chrXIII_598853r 27925 essential YMR168C 283 + ATACTGAAGAATGTATGTTT T|96|S T|96|I CEP3 CEntromere Protein 608.0 0 0 0 0 1.5096348097838357 P40969 0.9491789937019348 0.9472420215606691 0.8816057443618774 0.2263907939195633 0.4575999975204468 0.4174000024795532 0.5699999928474426 0.3222000002861023 35.37034623452439 25.0 0.0 no 10545 chrXIII_598882r 27926 essential YMR168C 254 + TACTAGAACACCAGCTAATT T|86|S T|86|I CEP3 CEntromere Protein 608.0 0 0 0 0 0.8298237212794988 P40969 0.9491789937019348 0.9472420215606691 0.6453543305397034 0.11137393116950987 -0.3964000046253204 0.6980000138282776 -0.8587999939918518 0.7185999751091003 41.34354078426686 35.0 0.0 no 10546 chrXIII_599052 27929 essential YMR168C 87 - CTCTTCCTGCAGTTTCCACA K|35|N silent|AAG>AAA|K|35 R|34|S silent|AGG>AGA|R|34 CEP3 CEntromere Protein 608.0 0 0 0 0 0.0469888941482101 P40969 0.9355990290641784 0.9087679982185364 0.017057590186595917 0.04007870703935623 57.3535319937883 50.0 0.0 no 10547 chrXIII_599093 27930 essential YMR168C 46 - GACTTTTCGCCTCGTACACA V|22|L V|22|I CEP3 CEntromere Protein 608.0 0 0 0 0 -0.18013019652034726 P40969 0.9539830088615416 0.9574310183525084 0.0 0.0 52.48176265108958 50.0 0.0 no 10548 chrXIII_599099 27931 essential YMR168C 40 - TCGCCTCGTACACACGGAAC R|19|S silent|AGG>AGA|R|19 R|20|P R|20|Q CEP3 CEntromere Protein 608.0 0 0 0 0 -0.9679967442038216 P40969 0.9087679982185364 0.9099509716033936 0.949662983417511 0.015172354876995087 0.0 0.0 51.89171084610689 60.0 0.0 no 10549 chrXIII_658731r 27934 essential YMR197C 445 + CACAAATAATGATGGATTTA Q|150|E Q|150|* VTI1 Vps10 (Ten) Interacting 217.0 0 1 0 0 0.727470412346449 Q04338 0.9590039849281312 0.1494569629430771 33.002936195177256 25.0 0.0 no 10550 chrXIII_658756r 27935 essential YMR197C 420 + GCAAATGAAACTGAAGGAAT A|141|G A|141|V VTI1 Vps10 (Ten) Interacting 217.0 0 0 0 0 -2.2725808307764743 Q04338 0.9484469890594482 0.9504740238189696 0.09256303310394287 0.007875721901655197 34.79113309060165 35.0 0.0 yes 10551 chrXIII_658808 27936 essential YMR197C 371 - CCGATTTCTGTAAGATTGCA silent|TCG>TCC|S|130 silent|TCG>TCA|S|130 VTI1 Vps10 (Ten) Interacting 217.0 0 0 0 0 -0.5186122808372474 Q04338 45.72083714323429 40.0 0.0 no 10552 chrXIII_658832 27939 essential YMR197C 347 - TGCTCAACAACTGTTGCCTT S|122|T S|122|N L|121|F silent|TTG>TTA|L|121 VTI1 Vps10 (Ten) Interacting 217.0 0 0 0 0 0.7275457794611684 Q04338 0.9512869715690612 0.9536849856376648 0.9587849974632264 0.09138555079698564 0.1809605658054352 0.0 50.21193525942709 45.0 0.0 no 10553 chrXIII_658906r 27940 essential YMR197C 270 + CTGCAATCCTTAGTAGACTC Q|92|E Q|92|* VTI1 Vps10 (Ten) Interacting 217.0 0 0 0 0 -0.6867398247483101 Q04338 0.9590039849281312 0.7602779865264893 0.02078000083565712 47.51249720989443 45.0 0.0 no 10554 chrXIII_658899 27942 essential YMR197C 280 - ACGATCGCCTGAGTCTACTA R|100|P R|100|H D|99|H D|99|N VTI1 Vps10 (Ten) Interacting 217.0 0 0 0 0 0.5592802676961117 Q04338 0.9099509716033936 0.9570810198783876 0.9486550092697144 0.956179976463318 0.012911726720631123 0.014786641113460062 0.01828846521675587 0.06310616433620453 -0.023560000583529472 -0.036419998854398734 51.25471234614747 50.0 0.0 no 10555 chrXIII_659027 27944 essential YMR197C 152 - CTACATCCATCTGATCTAGC V|57|L V|57|I D|56|H D|56|N VTI1 Vps10 (Ten) Interacting 217.0 0 0 0 0 1.126546849076019 Q04338 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 1.0 0.6852043271064758 0.09891950339078903 0.4571803212165833 -0.3769800066947937 -0.5999199748039246 -1.1592199802398682 -0.7022600173950195 -0.5874999761581421 -0.7113400101661682 48.52523429839789 45.0 0.0 no 10556 chrXIII_659097 27945 essential YMR197C 82 - TCTCTGTGATAACGGTTGTG Q|33|H silent|CAG>CAA|Q|33 R|34|T R|34|K VTI1 Vps10 (Ten) Interacting 217.0 0 0 0 0 -0.9792309344448468 Q04338 0.9570760130882264 0.932735025882721 0.955805003643036 0.11402203142642975 0.008026588708162308 0.04427938908338547 0.8135399818420409 3.3666400909423833 1.2487599849700928 45.88023415642362 45.0 0.0 no 10557 chrXIII_659133 27947 essential YMR197C 46 - GCTCGCTTTGGCTTGTTCTA silent|GCG>GCC|A|21 silent|GCG>GCA|A|21 S|22|T S|22|N VTI1 Vps10 (Ten) Interacting 217.0 0 0 1 Series([], Name: modification, dtype: object) 0 -0.6607348377383102 Q04338 0.9512869715690612 0.9536849856376648 0.04642033204436302 0.04064303636550903 -0.22944000363349915 -0.539359986782074 56.769524836587436 50.0 0.0 no 10558 chrXIII_664827 27948 essential YMR200W 75 + GACGAAAGTAACTCTATATA D|26|E silent|GAC>GAT|D|26 0 0 0 0 1.0698143776281621 Q03691 1.0 34.78207832359584 30.0 1.0 no 10559 chrXIII_664869 27949 essential YMR200W 117 + AATCAAGTGTTCACGGGACC Q|41|E Q|41|* 0 0 0 0 -0.04856044744963312 Q03691 0.8174945712089539 47.996966268840474 50.0 1.0 no 10560 chrXIII_664870 27950 essential YMR200W 118 + ATCAAGTGTTCACGGGACCG Q|41|E Q|41|* 0 0 0 0 0.5911082123739287 Q03691 0.8174945712089539 50.54121176941408 55.00000000000001 1.0 no 10561 chrXIII_664902r 27951 essential YMR200W 153 - TCTATCAATAGTTCATCTAC E|58|Q E|58|K L|56|F silent|TTG>TTA|L|56 0 0 0 0 0.3552797673545613 Q03691 0.0 0.0 0.38903379440307617 39.13504816693779 30.0 1.0 no 10562 chrXIII_664944 27953 essential YMR200W 192 + AGCTATTCGTTCACTGAAGA S|65|R silent|AGC>AGT|S|65 0 0 0 0 0.3503743290131984 Q03691 0.005116176791489124 44.983404206526814 40.0 1.0 no 10563 chrXIII_664948 27954 essential YMR200W 196 + ATTCGTTCACTGAAGATGGT S|67|W S|67|L 0 0 0 0 -0.7368308819771661 Q03691 0.0 0.0 44.911174628043064 40.0 1.0 no 10564 chrXIII_664988r 27956 essential YMR200W 239 - TACGAGGATTGCCACTTACC R|86|P R|86|H 0 0 0 0 0.8893216745300372 Q03691 0.11361543834209442 0.09772156178951263 50.26655591110386 50.0 1.0 no 10565 chrXIII_665006 27957 essential YMR200W 254 + TCGTAACCCAACTTGCCCCA R|86|G R|86|C N|87|K silent|AAC>AAT|N|87 0 0 0 0 0.7085894898310303 Q03691 0.12483266741037367 0.01854410395026207 0.19694197177886966 57.12415015466689 55.00000000000001 1.0 no 10566 chrXIII_665052 27961 essential YMR200W 300 + ACATATAACATTTCAGAAAA T|101|R T|101|I 0 1 0 0 -0.0030444274399165643 Q03691 0.12459461390972135 0.02778959274291992 30.825735099202404 20.0 1.0 no 10567 chrXIII_665121 27962 essential YMR200W 369 + AGCGACCCATGCAATGATGA S|124|R silent|AGC>AGT|S|124 D|125|E silent|GAC>GAT|D|125 0 0 0 0 -0.10565778680569038 Q03691 0.0 0.22964079678058624 50.108522309196026 50.0 1.0 no 10568 chrXIII_665091r 27963 essential YMR200W 342 - TGTCTACCGTCAACTTCAAT R|120|T R|120|K G|119|A G|119|D 0 0 0 0 -1.313701871890312 Q03691 0.0 0.0 0.0 0.0 46.0779044927769 40.0 1.0 no 10569 chrXIII_665178 27965 essential YMR200W 426 + ACTTTCAAGGAATATGCCGT T|143|S T|143|I F|144|L silent|TTC>TTT|F|144 0 1 0 0 -1.7640888434891178 Q03691 0.5325235724449158 0.6795940995216371 0.7244119048118591 45.563403129582355 40.0 1.0 no 10570 chrXIII_665228r 27966 essential YMR200W 479 - CATCATATTGGTACAATTGC D|166|H D|166|N 0 0 0 0 0.0942029304735021 Q03691 0.013150939717888832 0.3144026100635529 41.03165233989779 35.0 1.0 no 10571 chrXIII_665229 27967 essential YMR200W 477 + CTGCAATTGTACCAATATGA Q|161|E Q|161|* 0 0 0 0 0.003009183699908602 Q03691 0.2892216145992279 41.60015093180039 35.0 1.0 no 10572 chrXIII_665240r 27969 essential YMR200W 491 - GCATTGGAGTACCATCATAT M|170|I M|170|I 0 0 0 0 -0.4501032217023022 Q03691 0.11988546699285507 0.11988546699285507 47.47300125618562 40.0 1.0 no 10573 chrXIII_667554r 27973 high_effect YMR202W 20 - CTACAACACCAATCAACAAA V|13|L V|13|I V|12|L V|12|I ERG2 ERGosterol biosynthesis 222.0 0 0 0 0 -0.05220497232107008 P32352 0.9539830088615416 0.9574310183525084 0.9539830088615416 0.9574310183525084 0.9880402088165284 0.9226476550102234 0.766854465007782 0.3951014280319214 37.19823250402538 35.0 1.0 no 10574 chrXIII_667669 27974 high_effect YMR202W 132 + AGCAAACACAACGCAGCAGA S|45|R silent|AGC>AGT|S|45 H|47|D H|47|Y ERG2 ERGosterol biosynthesis 222.0 0 0 0 0 -0.8602943790334476 P32352 0.9417110085487366 0.9473130106925964 0.9489949941635132 0.2493308633565903 0.024411210790276527 0.3726519346237183 46.00771557907712 50.0 1.0 no 10575 chrXIII_667707r 27975 high_effect YMR202W 173 - CGTCTCTGACATCCTGTAAC D|64|H D|64|N R|63|T R|63|K ERG2 ERGosterol biosynthesis 222.0 0 0 0 0 0.06873158102415965 P32352 0.9486550092697144 0.956179976463318 0.932735025882721 0.955805003643036 0.11886098980903625 0.4849873483181 0.6240466237068176 0.6076370477676392 49.10879041664828 50.0 1.0 no 10576 chrXIII_667726 27976 high_effect YMR202W 189 + GACGCACTTGCCTCTCATTA D|64|E silent|GAC>GAT|D|64 A|65|G A|65|V ERG2 ERGosterol biosynthesis 222.0 0 0 0 0 -0.11964317961355668 P32352 0.9532920122146606 0.9484469890594482 0.9504740238189696 0.9738395810127258 0.3115456998348236 0.2306602448225021 53.66484544976385 50.0 1.0 no 10577 chrXIII_667727 27977 high_effect YMR202W 190 + ACGCACTTGCCTCTCATTAC A|65|G A|65|V D|64|E silent|GAC>GAT|D|64 ERG2 ERGosterol biosynthesis 222.0 0 0 0 0 0.8233470701095736 P32352 0.9484469890594482 0.9504740238189696 0.9532920122146606 0.3115456998348236 0.2306602448225021 0.9738395810127258 52.929714604265605 50.0 1.0 no 10578 chrXIII_667728 27978 high_effect YMR202W 191 + CGCACTTGCCTCTCATTACG A|65|G A|65|V L|66|V L|66|F ERG2 ERGosterol biosynthesis 222.0 0 0 0 0 0.06880144767410852 P32352 0.9484469890594482 0.9504740238189696 0.9512209892272948 0.9587849974632264 0.3115456998348236 0.2306602448225021 0.03225716948509216 0.1519882082939148 53.2749286144641 55.00000000000001 1.0 no 10579 chrXIII_667844r 27984 high_effect YMR202W 310 - TCCGAATAGAATTAAGTACT G|110|R G|110|R G|110|A G|110|E ERG2 ERGosterol biosynthesis 222.0 0 0 0 0 -1.7912419350716184 P32352 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.0 0.0 0.0 0.0 37.1668415706003 30.0 1.0 no 10580 chrXIII_667855 27985 high_effect YMR202W 318 + ATTCTATTCGGAACCGCTGT L|108|V silent|CTA>TTA|L|108 ERG2 ERGosterol biosynthesis 222.0 0 0 0 0 0.6325251543943831 P32352 0.9512209892272948 0.5761123299598694 49.53626367498492 45.0 1.0 no 10581 chrXIII_667912 27986 high_effect YMR202W 375 + GACTATTTTACCATCTTACA D|126|E silent|GAC>GAT|D|126 ERG2 ERGosterol biosynthesis 222.0 0 0 0 0 -0.37689055923363457 P32352 0.9532920122146606 0.01690310798585415 42.217922745453336 30.0 1.0 no 10582 chrXIII_667954r 27987 high_effect YMR202W 420 - ACTTCGGCTTCAGTGGCATA V|147|L V|147|I E|146|Q E|146|K ERG2 ERGosterol biosynthesis 222.0 0 0 0 0 0.1673476685732322 P32352 0.9539830088615416 0.9574310183525084 0.956179976463318 0.9475290179252625 0.2988235056400299 0.22250844538211825 0.030905254185199738 0.05479882284998894 54.12703075970336 50.0 1.0 no 10583 chrXIII_667984r 27988 high_effect YMR202W 450 - TTCAAGTGATGAGTCATACC L|156|F silent|TTG>TTA|L|156 ERG2 ERGosterol biosynthesis 222.0 0 0 0 0 -1.290959467624651 P32352 0.9587849974632264 0.03349020704627037 43.8404427640241 40.0 1.0 no 10584 chrXIII_668018r 27989 high_effect YMR202W 484 - ACCTGGCATGCTGTATTGCT G|168|R G|168|S G|168|A G|168|D ERG2 ERGosterol biosynthesis 222.0 0 0 0 0 1.3433564423575148 P32352 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.11179153621196747 0.5434119701385498 0.20317131280899048 0.4453570246696472 56.09314291567813 50.0 1.0 no 10585 chrXIII_668521 27992 essential YMR203W 29 + CTCTCAAATTCCCACTATCC S|11|C S|11|F Q|12|E Q|12|* TOM40 Translocase of the Outer Mitochondrial membrane 387.0 0 0 0 0 0.5918137652540147 P23644 0.054966259747743614 0.05970678851008415 0.9593973755836488 49.71025773085564 45.0 1.0 no 10586 chrXIII_668596 27993 essential YMR203W 104 + CCCAATATCTAGCTTTGTTG P|36|R P|36|L P|36|A P|36|S TOM40 Translocase of the Outer Mitochondrial membrane 387.0 0 0 0 0 0.2886124855072125 P23644 0.012224271893501282 0.01721429079771042 0.40978553891181946 0.06898779422044754 47.2069432185246 40.0 1.0 no 10587 chrXIII_668635 27996 essential YMR203W 143 + GCATTCTCACAGACAATCTT H|49|D H|49|Y S|50|C S|50|F TOM40 Translocase of the Outer Mitochondrial membrane 387.0 0 0 0 0 0.5253401610781926 P23644 0.6278319954872131 0.0774134173989296 0.03283243626356125 0.032630644738674164 45.913917041550924 40.0 1.0 no 10588 chrXIII_668641 27997 essential YMR203W 149 + TCACAGACAATCTTTGGAGC H|51|Q silent|CAC>CAT|H|51 H|51|D H|51|Y TOM40 Translocase of the Outer Mitochondrial membrane 387.0 0 0 0 0 -0.7751519786091186 P23644 0.3154349625110626 0.20694944262504575 1.0 45.450712798643856 45.0 1.0 no 10589 chrXIII_668669r 27999 essential YMR203W 180 - TTCAGGTTTTCCACGGTACC silent|CTG>CTC|L|66 silent|CTG>CTA|L|66 TOM40 Translocase of the Outer Mitochondrial membrane 387.0 0 0 0 0 -0.273982397157754 P23644 54.18507694736304 50.0 1.0 no 10590 chrXIII_668670r 28000 essential YMR203W 181 - ATTCAGGTTTTCCACGGTAC silent|CTG>CTC|L|66 silent|CTG>CTA|L|66 TOM40 Translocase of the Outer Mitochondrial membrane 387.0 0 0 0 0 0.6484840162456782 P23644 50.364399539993656 45.0 1.0 no 10591 chrXIII_668704r 28002 essential YMR203W 215 - ACTGAGACAAAAACACGTCA Q|78|H silent|CAG>CAA|Q|78 TOM40 Translocase of the Outer Mitochondrial membrane 387.0 0 0 0 0 0.28077763011003154 P23644 0.15097126364707947 38.574735693164094 40.0 1.0 no 10592 chrXIII_668789 28005 essential YMR203W 297 + ACCTCACACACTTTCTCTAT silent|ACC>ACG|T|100 silent|ACC>ACT|T|100 T|100|S T|100|I TOM40 Translocase of the Outer Mitochondrial membrane 387.0 0 0 0 0 -1.006946107415693 P23644 0.008653489872813225 0.4459960162639618 49.15760556225121 40.0 1.0 no 10593 chrXIII_668855 28007 essential YMR203W 363 + AACGATAACCTATTTGCTCA N|122|K silent|AAC>AAT|N|122 TOM40 Translocase of the Outer Mitochondrial membrane 387.0 0 0 0 0 0.6483279224544455 P23644 0.2142838090658188 42.51216206854798 35.0 1.0 no 10594 chrXIII_668904r 28010 essential YMR203W 415 - CCAACCATAGTTTAATCTAC W|145|S W|145|* G|144|A G|144|D TOM40 Translocase of the Outer Mitochondrial membrane 387.0 0 1 0 0 -0.5575607590231197 P23644 0.0 0.919411838054657 0.6308817863464355 41.73922050498789 35.0 1.0 no 10595 chrXIII_669040 28013 essential YMR203W 548 + GAACCCTTCGTTCTCTGAGA N|184|K silent|AAC>AAT|N|184 P|185|A P|185|S TOM40 Translocase of the Outer Mitochondrial membrane 387.0 0 0 0 0 -0.2719069731759657 P23644 0.0 0.0 0.0 52.16472518543111 50.0 1.0 no 10596 chrXIII_669249 28019 essential YMR203W 757 + GTGCTTTAATTGCATCGCTA A|254|G A|254|V TOM40 Translocase of the Outer Mitochondrial membrane 387.0 0 0 0 0 0.0024823206009425003 P23644 0.0373971052467823 1.0 48.0020356656172 40.0 1.0 no 10597 chrXIII_669307 28021 essential YMR203W 815 + AACTACATTACAAGCTGGTA T|273|S T|273|I T|274|R T|274|I TOM40 Translocase of the Outer Mitochondrial membrane 387.0 0 0 0 0 0.14828566884137293 P23644 0.09908856451511383 0.6045825481414795 0.09341334551572801 0.06734129786491394 41.06645432384346 35.0 1.0 no 10598 chrXIII_669331 28022 essential YMR203W 839 + TCCTATTACTGATCCATTGA P|281|R P|281|L P|281|A P|281|S TOM40 Translocase of the Outer Mitochondrial membrane 387.0 0 0 0 0 0.3053742643061681 P23644 0.18785400688648224 0.08373265713453293 0.2814904749393463 0.5207258462905884 46.092206151967495 35.0 1.0 no 10599 chrXIII_669332 28023 essential YMR203W 840 + CCTATTACTGATCCATTGAT P|281|R P|281|L TOM40 Translocase of the Outer Mitochondrial membrane 387.0 0 0 0 0 0.5756929360374934 P23644 0.18785400688648224 0.08373265713453293 45.09025225405924 35.0 1.0 no 10600 chrXIII_672599r 28026 high_effect YMR205C 2145 + ACTTTGTCTAACAATGTTCC T|716|S T|716|I PFK2 PhosphoFructoKinase 959.0 0 0 0 0 1.0036037775250652 P16862 0.14971034228801727 0.0030108639039099216 0.16660000383853912 0.7315999865531921 43.077838562441684 35.0 0.0 no 10601 chrXIII_672636r 28029 high_effect YMR205C 2108 + TCCAGCTTTCAGAATCCCAA P|704|R P|704|L P|704|A P|704|S PFK2 PhosphoFructoKinase 959.0 0 0 0 0 -0.5616245648660049 P16862 0.01872777938842773 0.06798877567052841 0.16811375319957733 0.03803389146924019 2.789999961853028 2.612799882888794 1.940600037574768 2.6136000156402592 51.68545867026501 45.0 0.0 no 10602 chrXIII_672764 28030 high_effect YMR205C 1983 - ATACCTAGATCTGCTTCTTC G|667|A G|667|D G|667|R G|667|S PFK2 PhosphoFructoKinase 959.0 0 0 0 0 0.3278926435025201 P16862 0.18088826537132266 0.5588096380233765 0.05833910033106804 0.1531323343515396 -0.1703999936580658 -1.1604000329971311 -0.8647999763488771 -0.44279998540878296 48.33582867964146 40.0 0.0 no 10603 chrXIII_672802 28032 high_effect YMR205C 1945 - ACCGATTTCAGAACCACCAC G|655|R G|655|S G|655|A G|655|D PFK2 PhosphoFructoKinase 959.0 0 1 0 0 -0.6667508714752376 P16862 0.0 0.0 0.0 0.0 3.2109999656677246 3.8787999153137207 3.3062000274658203 4.213200092315674 49.67630894259463 50.0 0.0 no 10604 chrXIII_672893r 28035 high_effect YMR205C 1851 + AGACCATACGCTATCTACAA P|619|A P|619|S P|619|R P|619|L PFK2 PhosphoFructoKinase 959.0 0 0 0 0 -0.3185649628895342 P16862 0.6752848625183105 0.1862996816635132 0.03552570566534996 0.13047657907009125 2.041800022125244 4.0097999572753915 7.543799877166747 6.372200012207031 44.621689939523385 40.0 0.0 no 10605 chrXIII_672920r 28038 high_effect YMR205C 1824 + GCTACTTACTGTATGTCCCA A|609|G A|609|V T|610|S T|610|I PFK2 PhosphoFructoKinase 959.0 0 0 0 0 -0.17588378971659385 P16862 0.00039819037192501133 1.0 0.5969094038009644 0.14385148882865906 1.6538000106811523 -0.1356000006198883 1.47160005569458 2.2135999202728267 53.1691285385777 45.0 0.0 no 10606 chrXIII_672942r 28039 high_effect YMR205C 1802 + CAACTCTGCCGTCTACTCGA N|602|K silent|AAC>AAT|N|602 S|603|C S|603|F PFK2 PhosphoFructoKinase 959.0 0 0 0 0 -0.7352477813082315 P16862 0.0 0.019366709515452385 0.007966210134327412 3.4261999130249023 1.0958000421524048 12.110400199890135 52.901352588303496 55.00000000000001 0.0 no 10607 chrXIII_673010 28041 high_effect YMR205C 1737 - CTCTTGTCCTTTGGTAGCTT K|585|N silent|AAG>AAA|K|585 PFK2 PhosphoFructoKinase 959.0 0 0 0 0 0.4422255105776253 P16862 0.14117936789989471 -0.0560000017285347 54.907354569841694 45.0 0.0 no 10608 chrXIII_673017r 28042 high_effect YMR205C 1727 + CAACGAACCAAAGCTACCAA N|577|K silent|AAC>AAT|N|577 PFK2 PhosphoFructoKinase 959.0 0 0 0 0 -0.3990453423303564 P16862 0.6371078491210938 -0.22020000219345093 42.430087430166786 45.0 0.0 no 10609 chrXIII_673157 28043 high_effect YMR205C 1590 - AACTTGACGGATTCCATTAA K|536|N silent|AAG>AAA|K|536 PFK2 PhosphoFructoKinase 959.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.39009993943402216 P16862 0.2796122431755066 0.670799970626831 41.56173429277783 35.0 0.0 no 10610 chrXIII_673203 28044 high_effect YMR205C 1544 - TAACAGCAATCAATGGTGAT V|521|L V|521|I A|520|P A|520|T PFK2 PhosphoFructoKinase 959.0 0 0 0 0 0.023098535666770004 P16862 0.24591293931007385 1.0 0.11797845363616945 0.372761994600296 -0.7874000072479248 -0.6679999828338623 4.006199836730957 0.6812000274658203 39.534949077840906 35.0 0.0 no 10611 chrXIII_673204 28045 high_effect YMR205C 1543 - AACAGCAATCAATGGTGATG V|521|L V|521|I A|520|P A|520|T PFK2 PhosphoFructoKinase 959.0 0 0 0 0 -2.1893734800983413 P16862 0.24591293931007385 1.0 0.11797845363616945 0.372761994600296 -0.7874000072479248 -0.6679999828338623 4.006199836730957 0.6812000274658203 40.08229104820799 40.0 0.0 yes 10612 chrXIII_673359 28050 high_effect YMR205C 1388 - ATCTGTCAACTAGAACTTTG R|469|T R|469|K D|468|H D|468|N PFK2 PhosphoFructoKinase 959.0 0 0 0 0 0.7031734807351124 P16862 0.23476675152778625 0.517253577709198 0.051555756479501724 0.7223811745643616 0.7278000116348267 -0.4411999881267548 0.1550000011920929 0.18299999833106995 39.48434039695934 35.0 0.0 no 10613 chrXIII_673495 28053 high_effect YMR205C 1252 - ATCTTGCCATTCGCTGGAAG D|424|H D|424|N W|422|C W|422|* PFK2 PhosphoFructoKinase 959.0 0 0 0 0 0.8912057110276772 P16862 0.015384239144623281 0.157697394490242 0.0 0.34040001034736633 0.25699999928474426 4.1041998863220215 50.995593930444784 50.0 0.0 no 10614 chrXIII_673691r 28056 high_effect YMR205C 1053 + TCCACCACGGATGCTACTAT silent|TCC>TCG|S|352 silent|TCC>TCT|S|352 S|352|C S|352|F PFK2 PhosphoFructoKinase 959.0 0 0 0 1 -0.3031907059537661 P16862 0.1616884171962738 0.006487450562417507 -0.14180000126361847 4.1571998596191415 52.42856874629399 50.0 0.0 no 10615 chrXIII_673802 28057 high_effect YMR205C 945 - AACAATTCCTCGATCAAAGA L|321|F silent|TTG>TTA|L|321 PFK2 PhosphoFructoKinase 959.0 0 1 0 0 -0.0736783183522215 P16862 0.010039561428129671 5.635200023651122 39.34741076671406 35.0 0.0 no 10616 chrXIII_673894 28060 high_effect YMR205C 853 - ACCGGCCTCAATCAAATGTT G|291|R G|291|S G|291|A G|291|D PFK2 PhosphoFructoKinase 959.0 0 0 0 0 0.02927642732434744 P16862 0.005733939819037914 0.01903466694056988 0.026231180876493454 0.01975052803754806 3.424599885940552 3.8877999782562256 2.645400047302246 3.873199939727783 48.83871320387686 45.0 0.0 no 10617 chrXIII_673938 28062 high_effect YMR205C 809 - GCTTCTTGAATTCCATACAA K|276|N silent|AAG>AAA|K|276 K|275|N silent|AAG>AAA|K|275 PFK2 PhosphoFructoKinase 959.0 0 0 0 0 0.07130306234992158 P16862 0.22502225637435916 0.2023516297340393 -1.1987999677658079 0.5070000290870667 43.79859084769907 35.0 0.0 no 10618 chrXIII_673954 28063 high_effect YMR205C 793 - ACAACGGGCAGTACCAATGT C|271|S C|271|Y R|270|P R|270|H PFK2 PhosphoFructoKinase 959.0 0 0 0 0 -2.624153487639008 P16862 0.35053592920303345 0.007740990724414588 0.0 0.0 0.8555999994277954 -0.26440000534057617 -0.02319999970495701 0.557200014591217 49.20839596898776 50.0 0.0 yes 10619 chrXIII_673993r 28065 high_effect YMR205C 751 + ACTGGGAAGACGTCCGTGGT H|251|Q silent|CAC>CAT|H|251 PFK2 PhosphoFructoKinase 959.0 0 1 0 0 -2.551220090123345 P16862 0.6798303127288818 -0.2594000101089477 54.56068526558022 60.0 0.0 yes 10620 chrXIII_674010r 28066 high_effect YMR205C 734 + ATACATCAAGGAATTCCACT Y|246|* silent|TAC>TAT|Y|246 I|247|M silent|ATC>ATT|I|247 PFK2 PhosphoFructoKinase 959.0 0 1 0 0 -0.4799821286745417 P16862 0.0794905349612236 -0.8565999865531921 42.09758897993351 35.0 0.0 no 10621 chrXIII_674146 28068 high_effect YMR205C 601 - ATCACCACCGGAAGTCATGA D|207|H D|207|N G|206|A G|206|D PFK2 PhosphoFructoKinase 959.0 0 1 0 0 -0.4138100521852098 P16862 0.0 0.0 0.0 0.0 -0.14259999990463254 -0.22360000014305115 -0.4679999947547913 -0.31859999895095825 50.46398044709008 50.0 0.0 no 10622 chrXIII_674185r 28072 high_effect YMR205C 559 + CTCTGCCAAAGCCATTGAAC L|188|V silent|CTG>TTG|L|188 P|189|A P|189|S PFK2 PhosphoFructoKinase 959.0 0 1 0 0 -0.2449634918623888 P16862 0.9106361269950868 0.8899974226951599 48.556223792714825 50.0 0.0 no 10623 chrXIII_674276r 28075 high_effect YMR205C 468 + CCAGAAGCTTCTGCTGAGTC P|157|R P|157|L PFK2 PhosphoFructoKinase 959.0 0 1 0 0 -0.0945061324236571 P16862 0.769521951675415 0.8032062649726868 53.453860862596066 55.00000000000001 0.0 no 10624 chrXIII_674348 28079 high_effect YMR205C 399 - ACACCAACAACGTTACCTAA G|139|A G|139|D V|140|L V|140|I PFK2 PhosphoFructoKinase 959.0 0 0 0 0 -1.3185232487360956 P16862 1.0 0.19362610578536987 0.09900408238172533 0.057287354022264474 43.410378257511006 40.0 0.0 no 10625 chrXIII_674372 28080 high_effect YMR205C 375 - TCCAAAGTGTACAACTGCAT L|131|F silent|TTG>TTA|L|131 D|132|H D|132|N PFK2 PhosphoFructoKinase 959.0 0 0 0 0 0.7281204296474642 P16862 0.6871711015701294 0.0 0.0 44.34056880622642 40.0 0.0 no 10626 chrXIII_674414r 28084 high_effect YMR205C 330 + GCTATGAACGCTCCTCTTCA A|111|G A|111|V PFK2 PhosphoFructoKinase 959.0 0 0 0 0 0.2899286461560366 P16862 0.4053468108177185 0.3033439815044403 52.90433342622669 50.0 0.0 no 10627 chrXIII_674481r 28085 high_effect YMR205C 263 + ATCACATGCCACCCAATCCT S|89|* S|89|L H|90|D H|90|Y PFK2 PhosphoFructoKinase 959.0 0 0 0 0 -0.6686176497004783 P16862 0.3726901113986969 0.6442197561264038 0.22120527923107147 55.794563219772776 50.0 0.0 no 10628 chrXIII_684475 28087 essential YMR208W 8 + ACCGTTCTTAACTTCTGCAC P|4|R P|4|L P|4|A P|4|S ERG12 ERGosterol biosynthesis 443.0 0 0 0 0 -1.7694827245967928 P07277 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.011710709892213345 0.01668759062886238 0.6392642259597778 0.07275232672691345 49.23220061945664 45.0 1.0 no 10629 chrXIII_684476 28088 essential YMR208W 9 + CCGTTCTTAACTTCTGCACC P|4|R P|4|L F|5|L silent|TTC>TTT|F|5 ERG12 ERGosterol biosynthesis 443.0 0 0 0 0 -1.467824684913267 P07277 0.9432820081710817 0.9430609941482544 0.9387490153312684 0.011710709892213345 0.01668759062886238 0.2598428428173065 52.45076772238866 50.0 1.0 no 10630 chrXIII_684610 28092 essential YMR208W 143 + TACTATTGAATTGGACTTCC T|49|S T|49|I ERG12 ERGosterol biosynthesis 443.0 0 0 0 0 0.7537677717258386 P07277 0.9491789937019348 0.9472420215606691 0.19096460938453674 0.1437627375125885 41.571905005452955 35.0 1.0 no 10631 chrXIII_684633 28093 essential YMR208W 166 + ACATTAGCTTTAATCATAAG D|56|E silent|GAC>GAT|D|56 ERG12 ERGosterol biosynthesis 443.0 0 0 0 0 0.5495358953494242 P07277 0.9532920122146606 0.0 35.019615641290386 25.0 1.0 no 10632 chrXIII_684694 28095 essential YMR208W 227 + AAACTCCCAAAAATTGGCCA N|77|K silent|AAC>AAT|N|77 S|78|C S|78|F ERG12 ERGosterol biosynthesis 443.0 0 0 0 0 -0.6355642537058582 P07277 0.9439849853515624 0.945252001285553 0.9294660091400146 0.9374960660934448 0.05070644989609718 0.05252592265605927 43.92071578343382 40.0 1.0 no 10633 chrXIII_684742 28097 essential YMR208W 275 + TCAGGAACTCGTTAGTCTTT Q|93|E Q|93|* ERG12 ERGosterol biosynthesis 443.0 0 0 0 0 0.2374817268084217 P07277 0.9590039849281312 1.0 46.38951950541679 40.0 1.0 no 10634 chrXIII_684846r 28102 essential YMR208W 382 - AAACTTAATATTCTTGGCAT K|133|N silent|AAG>AAA|K|133 ERG12 ERGosterol biosynthesis 443.0 0 0 0 0 0.18179985421255807 P07277 0.9355990290641784 0.5160038471221924 37.075188071286895 25.0 1.0 no 10635 chrXIII_684878 28103 essential YMR208W 411 + TCTACTTTACCCATCGGTGC S|138|C S|138|F T|139|S T|139|I ERG12 ERGosterol biosynthesis 443.0 0 0 0 0 0.31847704199095395 P07277 0.945252001285553 0.9294660091400146 0.9491789937019348 0.9472420215606691 0.0 0.0 0.1326119750738144 0.0043358742259442815 53.909521439013865 50.0 1.0 no 10636 chrXIII_684884 28105 essential YMR208W 417 + TTACCCATCGGTGCTGGGTT P|141|A P|141|S P|141|R P|141|L ERG12 ERGosterol biosynthesis 443.0 0 0 0 0 -0.47266113775702 P07277 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.0 0.0 0.0 0.0 58.426958328262636 55.00000000000001 1.0 no 10637 chrXIII_684935 28107 essential YMR208W 468 + GCCTTAGCTATGGCCTACTT silent|GCC>GCG|A|157 silent|GCC>GCT|A|157 A|157|G A|157|V ERG12 ERGosterol biosynthesis 443.0 0 0 0 0 -0.4893356251851833 P07277 0.9484469890594482 0.9504740238189696 0.07960540801286697 0.026292875409126282 57.16818992748523 50.0 1.0 no 10638 chrXIII_684936 28108 essential YMR208W 469 + CCTTAGCTATGGCCTACTTG silent|GCC>GCG|A|157 silent|GCC>GCT|A|157 A|159|G A|159|V ERG12 ERGosterol biosynthesis 443.0 0 0 0 0 1.0271092230348178 P07277 0.9484469890594482 0.9504740238189696 0.0 0.0 53.27697582263636 50.0 1.0 no 10639 chrXIII_684948r 28111 essential YMR208W 484 - TCCTATTAACCCCCCCAAGT G|168|R G|168|R G|168|A G|168|E ERG12 ERGosterol biosynthesis 443.0 0 0 0 0 -1.5096631793111688 P07277 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.1949930042028427 0.1949930042028427 0.3330232501029968 0.3296147286891937 57.83443687290867 50.0 1.0 no 10640 chrXIII_685056r 28112 essential YMR208W 592 - AGCGTTATCTATTCCTGAAG A|204|P A|204|T ERG12 ERGosterol biosynthesis 443.0 0 0 0 0 -0.010737830254207131 P07277 0.9573720097541808 0.9523990154266356 0.07505878806114198 1.0 4.3959999084472665 1.4586000442504885 45.298269408096935 40.0 1.0 no 10641 chrXIII_685057r 28113 essential YMR208W 593 - CAGCGTTATCTATTCCTGAA A|204|P A|204|T ERG12 ERGosterol biosynthesis 443.0 0 0 0 0 0.454250359814509 P07277 0.9573720097541808 0.9523990154266356 0.07505878806114198 1.0 4.3959999084472665 1.4586000442504885 46.52082592613999 40.0 1.0 no 10642 chrXIII_685058r 28114 essential YMR208W 594 - ACAGCGTTATCTATTCCTGA V|205|L V|205|M A|204|P A|204|T ERG12 ERGosterol biosynthesis 443.0 0 0 0 0 0.4306082972683291 P07277 0.9539830088615416 0.9587630033493042 0.9573720097541808 0.9523990154266356 0.02605370432138443 0.005260230973362923 0.07505878806114198 1.0 4.3959999084472665 1.4586000442504885 48.58265076574583 40.0 1.0 no 10643 chrXIII_685436 28119 essential YMR208W 969 + TCAATCGGTGTTTCTCATCC S|324|* S|324|L I|325|M silent|ATC>ATT|I|325 ERG12 ERGosterol biosynthesis 443.0 0 0 0 0 -1.1683646065012994 P07277 0.9298099875450134 0.9598389863967896 0.017344214022159576 0.025087594985961914 50.310262581418726 45.0 1.0 no 10644 chrXIII_689136 28120 essential YMR211W 53 + TCAATTCTTCAATATACAAG Q|19|E Q|19|* F|20|L silent|TTC>TTT|F|20 DML1 Drosophila melanogaster Misato-Like protein 475.0 0 0 0 0 0.14812857229403142 Q03652 0.922443985939026 0.9660270214080809 0.0 0.022797347977757454 33.58281409120605 25.0 1.0 no 10645 chrXIII_689249 28121 essential YMR211W 166 + ATGCACCACGTGCCTTACTT A|57|G A|57|V P|58|A P|58|S DML1 Drosophila melanogaster Misato-Like protein 475.0 0 0 0 0 0.1405519480703153 Q03652 0.9764879941940308 0.9757149815559388 1.0004199743270874 0.9926369786262512 0.1889868527650833 0.15294884145259854 0.0 0.0 55.087065261968405 50.0 1.0 no 10646 chrXIII_689250 28122 essential YMR211W 167 + TGCACCACGTGCCTTACTTT A|57|G A|57|V P|58|A P|58|S DML1 Drosophila melanogaster Misato-Like protein 475.0 0 0 0 0 -0.17060169673029554 Q03652 0.9764879941940308 0.9757149815559388 1.0004199743270874 0.9926369786262512 0.1889868527650833 0.15294884145259854 0.0 0.0 55.38335904701165 50.0 1.0 no 10647 chrXIII_689431r 28127 essential YMR211W 351 - TCTCTGTTCAAACAAGGCAG R|123|T R|123|K E|124|Q E|124|K DML1 Drosophila melanogaster Misato-Like protein 475.0 0 0 0 0 -1.8149394068526143 Q03652 0.9510110020637512 0.969380021095276 0.9857460260391236 0.9736970067024232 0.6106441020965576 0.9779430031776428 0.2896856963634491 0.3481643795967102 44.58739800124993 45.0 1.0 no 10648 chrXIII_689497r 28129 essential YMR211W 417 - CTCAAAATATTGAAACTTGA L|145|F silent|TTG>TTA|L|145 DML1 Drosophila melanogaster Misato-Like protein 475.0 0 0 0 0 0.6298187078498073 Q03652 0.9867290258407592 0.0 31.809521312133878 25.0 1.0 no 10649 chrXIII_689618r 28131 essential YMR211W 538 - AAACTCTTGCAAGTAATTTT E|185|D silent|GAG>GAA|E|185 E|185|Q E|185|K DML1 Drosophila melanogaster Misato-Like protein 475.0 0 0 0 0 0.06999751063303761 Q03652 0.9778879880905152 0.9857460260391236 0.9736970067024232 0.7350305914878845 0.10661213845014572 0.12413889914751053 36.52467725992807 25.0 1.0 no 10650 chrXIII_689691 28133 essential YMR211W 608 + CTTCAATCTTGTAAGTGATA F|204|L silent|TTC>TTT|F|204 DML1 Drosophila melanogaster Misato-Like protein 475.0 0 0 0 0 0.109509363475203 Q03652 0.9677240252494812 0.6452022194862366 38.63797620413345 30.0 1.0 no 10651 chrXIII_689738 28134 essential YMR211W 655 + GTGCTCTACTGGTGGAATTA A|220|G A|220|V L|221|V silent|CTA>TTA|L|221 DML1 Drosophila melanogaster Misato-Like protein 475.0 0 0 0 0 -0.5099678421553311 Q03652 0.9109870195388794 0.9102140069007874 0.9141610264778136 0.4273923635482788 0.17064933478832245 0.039351727813482285 48.62192665566618 45.0 1.0 no 10652 chrXIII_689829r 28135 essential YMR211W 749 - TCTTTGAAAGTCTTTTCATA K|256|N silent|AAG>AAA|K|256 DML1 Drosophila melanogaster Misato-Like protein 475.0 0 0 0 0 0.2584332414987943 Q03652 0.9665650129318236 0.03268064185976982 38.35943228847509 25.0 1.0 no 10653 chrXIII_689830r 28136 essential YMR211W 750 - TTCTTTGAAAGTCTTTTCAT K|256|N silent|AAG>AAA|K|256 DML1 Drosophila melanogaster Misato-Like protein 475.0 0 0 0 0 0.3458791901540794 Q03652 0.9665650129318236 0.03268064185976982 39.19267997090168 25.0 1.0 no 10654 chrXIII_689934 28140 essential YMR211W 851 + TGCTCCTGGACTAACTAATT A|285|G A|285|V P|286|A P|286|S DML1 Drosophila melanogaster Misato-Like protein 475.0 0 0 0 0 -0.9271817511205528 Q03652 0.9109870195388794 0.9102140069007874 0.9201790094375609 0.9116989970207214 0.3229593634605408 0.2643757164478302 0.7711836695671082 0.7567996978759766 45.549451912683246 40.0 1.0 no 10655 chrXIII_690008r 28141 essential YMR211W 928 - TCTTTGTTCAAGATTGCTTT R|316|T R|316|K DML1 Drosophila melanogaster Misato-Like protein 475.0 0 0 0 0 0.2759948549065443 Q03652 0.9002249836921692 0.9185940027236938 0.35658568143844604 0.9656493067741394 43.55878800666892 30.0 1.0 no 10656 chrXIII_690009r 28143 essential YMR211W 929 - TTCTTTGTTCAAGATTGCTT R|316|T R|316|K DML1 Drosophila melanogaster Misato-Like protein 475.0 0 0 0 0 0.29777762227507004 Q03652 0.9002249836921692 0.9185940027236938 0.35658568143844604 0.9656493067741394 43.55878800666881 30.0 1.0 no 10657 chrXIII_690056r 28144 essential YMR211W 976 - CGACGAATATCCTAAGGTAA silent|TCG>TCC|S|331 silent|TCG>TCA|S|331 DML1 Drosophila melanogaster Misato-Like protein 475.0 0 0 0 0 1.0807738806250096 Q03652 40.47033229329623 40.0 1.0 no 10658 chrXIII_693387r 28146 essential YMR213W 9 - CCTTTCACGTATATTGGTAC G|10|R G|10|S silent|GTG>GTC|V|8 silent|GTG>GTA|V|8 CEF1 CErevisiae homolog of cdc Five 590.0 0 0 0 0 0.2134054445875786 Q03654 0.941340982913971 0.951104998588562 0.006936196703463793 0.043949045240879066 45.87395428791365 40.0 1.0 no 10659 chrXIII_693388r 28147 essential YMR213W 10 - GCCTTTCACGTATATTGGTA G|10|R G|10|S G|10|A G|10|D CEF1 CErevisiae homolog of cdc Five 590.0 0 0 0 0 -2.7503143126213403 Q03654 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.006936196703463793 0.043949045240879066 0.19222809374332428 0.01055219490081072 49.13795860432765 40.0 1.0 yes 10660 chrXIII_693393r 28149 essential YMR213W 15 - ACACCGCCTTTCACGTATAT G|11|A G|11|D V|12|L V|12|I CEF1 CErevisiae homolog of cdc Five 590.0 0 0 0 0 -0.5076586738624045 Q03654 0.9499930143356324 0.9446240067481996 0.9539830088615416 0.9574310183525084 0.0 0.0 0.06539953500032425 0.2474605292081833 51.25089210405901 45.0 1.0 no 10661 chrXIII_693494r 28150 essential YMR213W 116 - TGGCAGTCTTTTTCTGCAAA A|45|P A|45|T CEF1 CErevisiae homolog of cdc Five 590.0 0 0 0 0 0.4136558874792355 Q03654 0.9573720097541808 0.9523990154266356 0.0 0.0 47.82712064317417 40.0 1.0 no 10662 chrXIII_693552r 28154 essential YMR213W 174 - AACTCTGTAAAATTCAACTT E|64|D silent|GAG>GAA|E|64 E|64|Q E|64|K CEF1 CErevisiae homolog of cdc Five 590.0 0 0 0 0 0.2537140558356949 Q03654 0.94931298494339 0.956179976463318 0.9475290179252625 0.4483236074447632 0.15371811389923096 0.17030280828475952 34.38336702681437 25.0 1.0 no 10663 chrXIII_693593r 28157 essential YMR213W 215 - CTCTTGCAAGATCTAGAAGT R|78|T R|78|K A|77|P A|77|T CEF1 CErevisiae homolog of cdc Five 590.0 0 0 0 0 0.8152841624467424 Q03654 0.932735025882721 0.955805003643036 0.9573720097541808 0.9523990154266356 0.0 0.0 0.020189935341477398 0.031181422993540764 43.346673648372985 40.0 1.0 no 10664 chrXIII_693670 28161 essential YMR213W 289 + TCTGCGTCGAAAGATATAAT silent|GTC>GTG|V|97 silent|GTC>GTT|V|97 C|98|W silent|TGC>TGT|C|98 CEF1 CErevisiae homolog of cdc Five 590.0 0 0 0 0 0.9980457531431228 Q03654 0.9286419749259948 0.0024537499994039536 38.941234005813044 35.0 1.0 no 10665 chrXIII_693767 28164 essential YMR213W 386 + TCCTAACGCTGAAACTCAAA P|130|R P|130|L P|130|A P|130|S CEF1 CErevisiae homolog of cdc Five 590.0 0 0 0 0 -0.1432611236883935 Q03654 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 41.113496730610905 40.0 1.0 no 10666 chrXIII_693795r 28166 essential YMR213W 417 - TCTTCCAAATCACCATTATC D|146|H D|146|N E|145|Q E|145|K CEF1 CErevisiae homolog of cdc Five 590.0 0 0 0 0 -0.2252030451216853 Q03654 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.013330075889825821 0.042269282042980194 0.13159652054309845 0.10891606658697127 43.981233423496796 35.0 1.0 no 10667 chrXIII_693865r 28168 essential YMR213W 487 - TCTTGTAGCCTTCTTACCTT R|169|T R|169|K CEF1 CErevisiae homolog of cdc Five 590.0 0 0 0 0 0.2262436870701425 Q03654 0.932735025882721 0.955805003643036 0.0 0.0 53.326031290728785 40.0 1.0 no 10668 chrXIII_693866r 28169 essential YMR213W 488 - TTCTTGTAGCCTTCTTACCT R|169|T R|169|K CEF1 CErevisiae homolog of cdc Five 590.0 0 0 0 0 0.2632043652547645 Q03654 0.932735025882721 0.955805003643036 0.0 0.0 53.326031290728785 40.0 1.0 no 10669 chrXIII_693880 28170 essential YMR213W 499 + CTACAAGAAAGATTAGAGAG T|168|R T|168|I CEF1 CErevisiae homolog of cdc Five 590.0 0 0 0 0 -0.750277328296805 Q03654 0.9476869702339172 0.9472420215606691 0.006076820194721222 0.006690032780170441 32.9309347643196 35.0 1.0 no 10670 chrXIII_693922 28171 essential YMR213W 541 + GCATTGCTGAACTACAAAAG silent|CGC>CGG|R|181 silent|CGC>CGT|R|181 A|183|G A|183|V CEF1 CErevisiae homolog of cdc Five 590.0 0 0 0 0 0.41337733480533584 Q03654 0.9484469890594482 0.9504740238189696 0.0 0.0 39.030100116987626 40.0 1.0 no 10671 chrXIII_694006r 28172 essential YMR213W 628 - ATCTTCATTGTAATCAATGT D|216|H D|216|N E|215|Q E|215|K CEF1 CErevisiae homolog of cdc Five 590.0 0 0 0 0 0.5760473630380664 Q03654 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.0 0.0 0.07951373606920242 0.17743033170700073 38.385518689155454 25.0 1.0 no 10672 chrXIII_694206 28173 essential YMR213W 825 + CACGTTGAGAAAGCAGCACT H|276|Q silent|CAC>CAT|H|276 CEF1 CErevisiae homolog of cdc Five 590.0 0 0 0 0 0.2928744591037778 Q03654 0.9588389992713928 0.6548851132392883 46.65178064313182 50.0 1.0 no 10673 chrXIII_694266 28175 essential YMR213W 885 + AAACTTATACTATCTGCACC L|297|V L|297|F CEF1 CErevisiae homolog of cdc Five 590.0 0 0 0 0 0.37854876813381627 Q03654 0.9512209892272948 0.9587849974632264 0.03083057701587677 0.14266860485076904 41.46464001494286 35.0 1.0 no 10674 chrXIII_694397r 28180 essential YMR213W 1019 - TATCTTCTTGGCCGGAGTCG D|346|H D|346|N E|345|Q E|345|K CEF1 CErevisiae homolog of cdc Five 590.0 0 1 0 0 -0.8990285546734238 Q03654 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.13210779428482056 0.4849327802658081 0.5879445075988771 0.9164741635322572 54.29798426977084 55.00000000000001 1.0 no 10675 chrXIII_694506r 28185 essential YMR213W 1128 - ACAATTTCGAAATCGTTCTT V|383|L V|383|I CEF1 CErevisiae homolog of cdc Five 590.0 0 1 0 0 0.4154487101979527 Q03654 0.9539830088615416 0.9574310183525084 0.5568683743476868 0.870412290096283 38.86920578385622 30.0 1.0 no 10676 chrXIII_704395 28189 essential YMR218C 2473 - CCCATCGAAAGTAATTAACG G|831|R G|831|R G|831|A G|831|E TRS130 TRapp Subunit 1102.0 0 0 0 0 -1.5260809244654814 Q03660 0.5309609174728394 0.5309609174728394 0.902836263179779 1.0 39.81701644536479 40.0 0.0 no 10677 chrXIII_704396r 28191 essential YMR218C 2469 + CCCGCGTTAATTACTTTCGA silent|CCC>CCG|P|824 silent|CCC>CCT|P|824 P|824|R P|824|L TRS130 TRapp Subunit 1102.0 0 0 0 0 0.124387268929008 Q03660 0.08150705695152283 0.5975435972213745 49.09487354749389 45.0 0.0 no 10678 chrXIII_704508r 28193 essential YMR218C 2357 + TCTTCTAAACTCTTCAGTCA L|787|V L|787|F L|788|V silent|CTA>TTA|L|788 TRS130 TRapp Subunit 1102.0 0 0 0 0 -0.5641664042748608 Q03660 0.2558088600635529 0.3195512592792511 0.0 43.961318411688175 35.0 0.0 no 10679 chrXIII_704509r 28194 essential YMR218C 2356 + TTCTTCTAAACTCTTCAGTC L|787|V L|787|F L|788|V silent|CTA>TTA|L|788 TRS130 TRapp Subunit 1102.0 0 0 0 0 -0.8668640914983796 Q03660 0.2558088600635529 0.3195512592792511 0.0 42.8056533806689 35.0 0.0 no 10680 chrXIII_704710r 28197 essential YMR218C 2155 + ATACTCCATTCGAGAACGTT T|720|S T|720|I P|721|A P|721|S TRS130 TRapp Subunit 1102.0 0 0 0 0 -0.0029568775408376487 Q03660 0.7700166702270508 0.17938394844532013 0.7347389459609985 0.7055614590644836 44.944603539104044 40.0 0.0 no 10681 chrXIII_704970r 28201 essential YMR218C 1895 + TACTTTTGTAAAGGAGTTTC T|633|S T|633|I TRS130 TRapp Subunit 1102.0 0 0 0 0 -0.5355266039750908 Q03660 0.09777735918760301 0.010232274420559406 38.095712249355024 30.0 0.0 no 10682 chrXIII_704996r 28202 essential YMR218C 1869 + TCTTTCGAAATCATTGTTGA S|624|C S|624|F F|625|L silent|TTC>TTT|F|625 TRS130 TRapp Subunit 1102.0 0 0 0 0 1.108815898575248 Q03660 0.03504767268896103 0.04467247426509857 1.0 39.563951316639475 30.0 0.0 no 10683 chrXIII_704997r 28203 essential YMR218C 1868 + TTCTTTCGAAATCATTGTTG S|624|C S|624|F F|625|L silent|TTC>TTT|F|625 TRS130 TRapp Subunit 1102.0 0 0 0 0 -0.5479103546310019 Q03660 0.03504767268896103 0.04467247426509857 1.0 38.62325313332997 30.0 0.0 no 10684 chrXIII_705079 28204 essential YMR218C 1789 - TTTCTTCAAAAGAAAATCAC K|602|N silent|AAG>AAA|K|602 L|601|F silent|TTG>TTA|L|601 TRS130 TRapp Subunit 1102.0 0 0 0 0 -1.0755061907648968 Q03660 0.5234549641609192 0.3275664746761322 31.179566531984218 25.0 0.0 no 10685 chrXIII_705251 28205 essential YMR218C 1617 - ACTTCGAATAGCCCATCTAA V|546|L V|546|I E|545|Q E|545|K TRS130 TRapp Subunit 1102.0 0 0 0 0 0.9034106648765544 Q03660 0.5837123990058899 1.0 0.5895844101905823 0.9326849579811096 46.406489996167814 40.0 0.0 no 10686 chrXIII_705263r 28207 essential YMR218C 1602 + CATCTAATGTATCCTTTAGA L|536|V silent|CTA>TTA|L|536 TRS130 TRapp Subunit 1102.0 0 0 0 0 0.4223180001884173 Q03660 0.06391338258981705 41.02945740179314 30.0 0.0 no 10687 chrXIII_705419 28211 essential YMR218C 1449 - ATCTGTAAGACGTCTAATTT Q|489|H silent|CAG>CAA|Q|489 TRS130 TRapp Subunit 1102.0 0 0 0 0 0.4247729849502561 Q03660 0.07657735049724579 39.17481793857945 30.0 0.0 no 10688 chrXIII_705420 28212 essential YMR218C 1448 - TCTGTAAGACGTCTAATTTG Q|489|H silent|CAG>CAA|Q|489 TRS130 TRapp Subunit 1102.0 0 0 0 0 0.3414489045132519 Q03660 0.07657735049724579 39.20008319864968 35.0 0.0 no 10689 chrXIII_705426 28213 essential YMR218C 1442 - AGACGTCTAATTTGGGGCAG V|487|L V|487|I D|486|H D|486|N TRS130 TRapp Subunit 1102.0 0 0 0 0 0.7767640718115087 Q03660 0.7577823400497437 0.5078206658363342 0.0915767028927803 0.481761634349823 48.149530539598 50.0 0.0 no 10690 chrXIII_705623r 28214 essential YMR218C 1242 + TCTCTCTTCAACAAATGTGA L|416|V L|416|F S|415|C S|415|F TRS130 TRapp Subunit 1102.0 0 0 0 0 0.3706027835951537 Q03660 0.34859246015548706 0.20378117263317108 0.03219705820083618 0.017992584034800533 41.08767257150686 35.0 0.0 no 10691 chrXIII_706098r 28220 essential YMR218C 767 + TTCTAAATCAGATGAATCAC S|257|C S|257|F TRS130 TRapp Subunit 1102.0 0 1 0 0 -0.8751176834023869 Q03660 0.06714890897274017 0.09028628468513487 34.90866114597719 30.0 0.0 no 10692 chrXIII_706152 28223 essential YMR218C 716 - CCGGCATATTCATGTTTCTA silent|CCG>CCC|P|245 silent|CCG>CCA|P|245 M|244|I M|244|I TRS130 TRapp Subunit 1102.0 0 0 0 0 0.2605122160360876 Q03660 0.39677539467811584 0.39677539467811584 48.934144777789975 40.0 0.0 no 10693 chrXIII_706289r 28224 essential YMR218C 576 + TCGTTGGCCAATTTACAAAA S|193|W S|193|L TRS130 TRapp Subunit 1102.0 0 0 0 0 0.6462665601413247 Q03660 0.04554515331983566 0.3820257782936096 41.43441477134604 35.0 0.0 no 10694 chrXIII_706305r 28225 essential YMR218C 560 + GACACATTTGCAACATTCGT T|188|R T|188|I H|189|D H|189|Y TRS130 TRapp Subunit 1102.0 0 0 0 0 0.6793819123543219 Q03660 0.2761276364326477 0.09544497728347777 0.2245926707983017 1.0 44.6590421300516 40.0 0.0 no 10695 chrXIII_706384 28227 essential YMR218C 484 - CCAAAACTCCTGCCTTTCTT W|168|S W|168|* E|166|D silent|GAG>GAA|E|166 TRS130 TRapp Subunit 1102.0 0 0 0 0 0.8927145238081821 Q03660 0.0 0.22385680675506592 51.14184079442202 45.0 0.0 no 10696 chrXIII_706359r 28229 essential YMR218C 506 + CCAATTTAGCCAAAAGATTA Q|170|E Q|170|* TRS130 TRapp Subunit 1102.0 0 0 0 0 0.6225674348332807 Q03660 0.10724151134490968 38.762699862917145 30.0 0.0 no 10697 chrXIII_706470r 28232 essential YMR218C 395 + ATTCAAATCGGTATCCCTAA F|133|L silent|TTC>TTT|F|133 TRS130 TRapp Subunit 1102.0 0 0 0 0 -0.13870958137538392 Q03660 0.0 43.78719676819026 35.0 0.0 no 10698 chrXIII_706482r 28233 essential YMR218C 383 + GGACTCTAACCTATTCAAAT D|129|E silent|GAC>GAT|D|129 S|130|C S|130|F TRS130 TRapp Subunit 1102.0 0 0 0 0 0.5831170460405009 Q03660 0.035828430205583565 0.007714007515460253 0.006205384153872728 41.05797480603178 35.0 0.0 no 10699 chrXIII_706623r 28237 essential YMR218C 242 + TATCTCTATCGACCAATACA I|82|M silent|ATC>ATT|I|82 S|83|C S|83|F TRS130 TRapp Subunit 1102.0 0 0 0 0 0.1144964525933764 Q03660 0.16702120006084442 0.0 0.0 42.50712364920372 35.0 0.0 no 10700 chrXIII_706694 28239 essential YMR218C 174 - TCTGCCTCCCCTCTACCTTC D|65|H D|65|N A|64|P A|64|T TRS130 TRapp Subunit 1102.0 0 1 0 0 0.32620493072441303 Q03660 0.12898992002010345 0.5143216848373413 0.23421655595302585 0.4785175919532776 65.55974183116007 60.0 0.0 no 10701 chrXIII_706757r 28241 essential YMR218C 108 + ATACATTGGAAGGCATTTGA H|38|D H|38|Y TRS130 TRapp Subunit 1102.0 0 0 0 0 -0.4800126411505203 Q03660 0.0 0.0 41.955350799786636 35.0 0.0 no 10702 chrXIII_712341r 28245 essential YMR220W 28 - AGCTAGTAACGCTTTCCCTG A|16|P A|16|T ERG8 ERGosterol biosynthesis 451.0 0 0 0 0 -0.2294154142421737 P24521 0.9573720097541808 0.9523990154266356 0.0 0.0 52.7528854635197 50.0 1.0 no 10703 chrXIII_712342r 28246 essential YMR220W 29 - CAGCTAGTAACGCTTTCCCT A|16|P A|16|T ERG8 ERGosterol biosynthesis 451.0 0 0 0 0 0.41621111714197023 P24521 0.9573720097541808 0.9523990154266356 0.0 0.0 54.0075488674534 50.0 1.0 no 10704 chrXIII_712396 28249 essential YMR220W 80 + AGCATTTGTAGTCGGATTAT A|28|G A|28|V ERG8 ERGosterol biosynthesis 451.0 0 0 0 0 0.44708130366073295 P24521 0.9484469890594482 0.9504740238189696 0.07440826296806335 0.0254771001636982 44.8514700458826 35.0 1.0 no 10705 chrXIII_712437r 28250 essential YMR220W 124 - TTGCAATGAACCGTAAGGAT L|47|F silent|TTG>TTA|L|47 ERG8 ERGosterol biosynthesis 451.0 0 0 0 0 -1.2322646546763705 P24521 0.9587849974632264 0.0685025304555893 42.459045560986574 40.0 1.0 no 10706 chrXIII_712439 28251 essential YMR220W 123 + CATCCTTACGGTTCATTGCA P|43|A P|43|S P|43|R P|43|L ERG8 ERGosterol biosynthesis 451.0 0 0 0 0 0.6161300737666953 P24521 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 1.0 0.8852625489234924 0.6439959406852722 0.7467895746231079 51.20827266548463 45.0 1.0 no 10707 chrXIII_712544 28253 essential YMR220W 228 + TTCATTCCTGTTTCGATAGG F|77|L silent|TTC>TTT|F|77 P|79|A P|79|S ERG8 ERGosterol biosynthesis 451.0 0 0 0 0 0.5345461444320887 P24521 0.9387490153312684 0.9562489986419678 0.9498909711837769 0.30489593744277954 0.9427695274353028 0.8580505251884459 47.12161846889353 40.0 1.0 no 10708 chrXIII_712622r 28254 essential YMR220W 309 - TTGCAGTAGTCGTCCATGTT C|109|S C|109|Y ERG8 ERGosterol biosynthesis 451.0 0 0 0 0 0.07076553715620433 P24521 0.9421560168266296 0.9290120005607604 0.3719170093536377 0.4053130745887756 53.33852402637433 45.0 1.0 no 10709 chrXIII_712609 28255 essential YMR220W 293 + TAGCTACTTTAAACCTAACA S|99|R silent|AGC>AGT|S|99 Y|100|* silent|TAC>TAT|Y|100 ERG8 ERGosterol biosynthesis 451.0 0 0 0 0 0.5397553266033105 P24521 0.9417110085487366 0.4541000723838806 38.9763788486988 30.0 1.0 no 10710 chrXIII_712710r 28257 essential YMR220W 397 - TCTTCTGTTGCCACGATGTT R|139|T R|139|K R|138|T R|138|K ERG8 ERGosterol biosynthesis 451.0 0 0 0 0 -1.0281568515126909 P24521 0.932735025882721 0.955805003643036 0.932735025882721 0.955805003643036 0.4512505829334259 1.0 0.1004442572593689 1.0 52.52669736801585 45.0 1.0 no 10711 chrXIII_712801 28259 essential YMR220W 485 + CACAGTTTTAACTACAGCTT T|163|R T|163|I ERG8 ERGosterol biosynthesis 451.0 0 0 0 0 0.21280555320585776 P24521 0.9476869702339172 0.9472420215606691 0.0136747183278203 0.022089537233114243 42.81646330575978 35.0 1.0 no 10712 chrXIII_712785r 28260 essential YMR220W 472 - AACTGTGACTAAACCTGCCG V|164|L V|164|I ERG8 ERGosterol biosynthesis 451.0 0 0 0 0 0.2262150776654941 P24521 0.9539830088615416 0.9574310183525084 0.07225969433784485 0.10248331725597383 46.91051639932493 50.0 1.0 no 10713 chrXIII_712986r 28265 essential YMR220W 673 - TGGCAAATTAGAGATTAATG L|230|F silent|TTG>TTA|L|230 ERG8 ERGosterol biosynthesis 451.0 0 0 0 0 -0.29210004824710706 P24521 0.9587849974632264 0.13053782284259796 34.539639871937084 30.0 1.0 no 10714 chrXIII_712994 28266 essential YMR220W 678 + ATCTCTAATTTGCCAGATAT I|227|M silent|ATC>ATT|I|227 S|228|C S|228|F ERG8 ERGosterol biosynthesis 451.0 0 0 0 0 0.02298516264614519 P24521 0.9598389863967896 0.945252001285553 0.9294660091400146 0.01154796965420246 0.053264778107404716 0.052487168461084366 42.762032206684474 30.0 1.0 no 10715 chrXIII_713029 28268 essential YMR220W 713 + CGGCAGTAAACTGGCGCATT silent|GGC>GGG|G|239 silent|GGC>GGT|G|239 ERG8 ERGosterol biosynthesis 451.0 0 0 0 0 -0.12878756802119845 P24521 50.98644750447431 55.00000000000001 1.0 no 10716 chrXIII_713098 28269 essential YMR220W 782 + TTCGGGATTAACTTTATGGA S|262|W S|262|L ERG8 ERGosterol biosynthesis 451.0 0 0 0 0 0.5360650019219436 P24521 0.9288619756698608 0.9298099875450134 0.03985552117228508 0.3720566928386688 41.81681272882157 35.0 1.0 no 10717 chrXIII_723236 28276 essential YMR227C 1130 - CACTTTCAAAAGCAGCGCCT S|383|T S|383|N E|382|Q E|382|K TAF7 TATA binding protein-Associated Factor 590.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.6154709274708461 Q05021 0.9512869715690612 0.9536849856376648 0.956179976463318 0.9475290179252625 0.6070473194122314 0.5131011009216309 0.4927728176116944 0.7161963582038879 49.89626591292017 50.0 0.0 no 10718 chrXIII_723322r 28278 essential YMR227C 1041 + CACACAATTGCTTCGGCAGT H|348|Q silent|CAC>CAT|H|348 T|349|R T|349|I TAF7 TATA binding protein-Associated Factor 590.0 0 0 0 0 1.1619215068997344 Q05021 0.9588389992713928 0.9476869702339172 0.9472420215606691 0.4468353688716888 0.5419064164161682 0.22178220748901367 50.52879111479654 50.0 0.0 no 10719 chrXIII_723517 28283 essential YMR227C 849 - TCTACATAGTCTATTTCATT E|290|Q E|290|K V|289|L V|289|I TAF7 TATA binding protein-Associated Factor 590.0 0 0 0 0 -1.205481739449254 Q05021 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.02492252737283707 0.01961291953921318 0.1404002010822296 0.6517554521560669 -0.3925600051879883 -0.5464800000190735 -0.9436799883842468 -0.8079000115394592 40.21882952859829 25.0 0.0 no 10720 chrXIII_723518 28284 essential YMR227C 848 - CTACATAGTCTATTTCATTA V|289|L V|289|I TAF7 TATA binding protein-Associated Factor 590.0 0 0 0 0 0.4584808230719467 Q05021 0.9539830088615416 0.9574310183525084 0.1404002010822296 0.6517554521560669 -0.9436799883842468 -0.8079000115394592 38.66359321871232 25.0 0.0 no 10721 chrXIII_723549r 28285 essential YMR227C 814 + TTCGAAATAGACGATTTAGA R|273|G R|273|* TAF7 TATA binding protein-Associated Factor 590.0 0 0 0 0 0.8369654208343976 Q05021 0.8994590044021606 0.04805562272667885 3.773380041122437 35.51166000574909 30.0 0.0 no 10722 chrXIII_723644r 28287 essential YMR227C 719 + TGCGCCTTTAAGTGATATGG A|241|G A|241|V P|242|A P|242|S TAF7 TATA binding protein-Associated Factor 590.0 0 0 0 0 -0.7631139235507898 Q05021 0.9484469890594482 0.9504740238189696 0.9562489986419678 0.9498909711837769 1.0 0.1545301228761673 0.8490546941757202 0.7822683453559875 0.17550000548362732 1.2541199922561646 0.8375999927520752 0.5547599792480469 47.376971190545255 45.0 0.0 no 10723 chrXIII_724000 28292 essential YMR227C 366 - ACAAACTCTAACTGTATGTC V|129|L V|129|I E|127|D silent|GAG>GAA|E|127 TAF7 TATA binding protein-Associated Factor 590.0 0 0 0 0 -0.1559934760036002 Q05021 0.9539830088615416 0.9574310183525084 0.94931298494339 0.18218673765659327 0.3573659360408783 0.4670292139053345 -0.07586000114679338 -0.01104000024497509 0.8810600042343141 38.65815937042589 35.0 0.0 no 10724 chrXIII_724036 28293 essential YMR227C 330 - ATCACACCACTCTCTATGAG silent|GTG>GTC|V|116 silent|GTG>GTA|V|116 V|116|L V|116|M TAF7 TATA binding protein-Associated Factor 590.0 0 0 0 0 0.2974977872857273 Q05021 0.9539830088615416 0.9587630033493042 0.03962507471442223 0.007563238963484764 -1.405500054359436 -1.3411999940872192 47.55199241789678 45.0 0.0 no 10725 chrXIII_724037 28294 essential YMR227C 329 - TCACACCACTCTCTATGAGA V|116|L V|116|M silent|GTG>GTC|V|116 silent|GTG>GTA|V|116 TAF7 TATA binding protein-Associated Factor 590.0 0 0 0 0 -0.5201457321472303 Q05021 0.9539830088615416 0.9587630033493042 0.03962507471442223 0.007563238963484764 -1.405500054359436 -1.3411999940872192 48.812033247149145 45.0 0.0 no 10726 chrXIII_724093 28296 essential YMR227C 273 - GCTTCCCCAGGAATTCTAAT A|98|P A|98|T E|97|Q E|97|K TAF7 TATA binding protein-Associated Factor 590.0 0 1 0 0 -1.7646480366102866 Q05021 0.9573720097541808 0.9523990154266356 0.956179976463318 0.9475290179252625 0.01964188739657402 0.014327462762594225 0.02622346393764019 0.0206866767257452 -0.3391200006008148 -0.06063999980688095 -0.14176000654697418 -0.13524000346660614 51.62055225020475 45.0 0.0 no 10727 chrXIII_724135 28298 essential YMR227C 231 - GCCTTGTGTATCTTCTTAAC K|83|N silent|AAG>AAA|K|83 A|84|P A|84|T TAF7 TATA binding protein-Associated Factor 590.0 0 0 0 0 -0.3722170016368343 Q05021 0.9355990290641784 0.9573720097541808 0.9523990154266356 0.030211493372917175 0.05648676678538321 0.5013192296028137 47.98422839318971 40.0 0.0 no 10728 chrXIII_724297 28299 essential YMR227C 69 - ATGCGAATTCTCTTTAGTTT R|29|P R|29|H TAF7 TATA binding protein-Associated Factor 590.0 0 0 0 0 0.5299697748633034 Q05021 0.9099509716033936 0.9570810198783876 0.19385072588920596 0.06841118633747101 42.67885978222677 30.0 0.0 no 10729 chrXIII_727223r 28301 essential YMR229C 3878 + GGCACATATTACTGAAATTG A|1294|G A|1294|V H|1295|D H|1295|Y RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 1.1945404640487616 Q05022 0.05621785670518875 0.033363286405801766 0.0 0.0 38.48214699126606 35.0 0.0 no 10730 chrXIII_727244r 28302 essential YMR229C 3857 + CACTGTTAATGTTACTGGTT T|1287|S T|1287|I RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 -0.1240881761459817 Q05022 0.3930065035820007 0.016076840460300446 43.11942117023551 35.0 0.0 no 10731 chrXIII_727329 28303 essential YMR229C 3775 - ACCAGCCTTAATGTCTGAAT G|1265|R G|1265|S G|1265|A G|1265|D RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 -0.19399534030081764 Q05022 0.013074297457933426 0.04906327649950981 0.019660724326968197 0.18156759440898892 47.29650542592026 40.0 0.0 no 10732 chrXIII_727330r 28304 essential YMR229C 3771 + ACCTATTCAGACATTAAGGC silent|ACC>ACG|T|1258 silent|ACC>ACT|T|1258 T|1258|S T|1258|I RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 -0.6250642664160497 Q05022 1.0 0.1516839563846588 44.66123879868935 40.0 0.0 no 10733 chrXIII_727435 28305 essential YMR229C 3669 - TTTCCCAAAACGTATTGCAT G|1229|A G|1229|E G|1229|R G|1229|R RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 -2.0013273082466783 Q05022 0.0 0.0 0.0 0.0 44.0802187869096 35.0 0.0 no 10734 chrXIII_727438r 28306 essential YMR229C 3663 + AAGCCTATGCAATACGTTTT P|1223|A P|1223|S P|1223|R P|1223|L RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 0.5783396783843666 Q05022 0.3256884217262268 0.05949977785348892 0.04015713557600975 0.6070621609687805 44.39599477215575 35.0 0.0 no 10735 chrXIII_727478r 28307 essential YMR229C 3623 + ACTATCTGATTCTTACTTGA L|1209|V silent|CTA>TTA|L|1209 S|1210|C S|1210|F RRP5 Ribosomal RNA Processing 1729.0 0 1 0 0 -0.03995819438554227 Q05022 0.06303538382053375 0.004378609359264375 0.002278778469190001 41.274617575207635 30.0 0.0 no 10736 chrXIII_727854 28313 essential YMR229C 3250 - TTCATCACCAACTTTAATTG E|1090|Q E|1090|K D|1089|H D|1089|N RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 -0.3894235256639874 Q05022 0.6079128384590149 0.944734275341034 0.07012002170085907 0.27429255843162537 39.335436991665354 30.0 0.0 no 10737 chrXIII_727887 28314 essential YMR229C 3217 - GTCAACATGACTCTTTCCAA D|1079|H D|1079|N V|1078|L V|1078|I RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 0.5412364890051564 Q05022 0.14468403160572052 0.4980705380439758 0.4147534072399139 0.2815566658973694 45.68766579960163 40.0 0.0 no 10738 chrXIII_727921r 28316 essential YMR229C 3180 + GCCTCTATTGACCGCGAGCA silent|GCC>GCG|A|1061 silent|GCC>GCT|A|1061 A|1061|G A|1061|V RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 0.05809445139062575 Q05022 0.3976984918117523 0.5521778464317322 58.025571819266084 60.0 0.0 no 10739 chrXIII_728042r 28317 essential YMR229C 3059 + AACAATTTCTCCAGTTTTGA T|1021|R T|1021|I RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 0.8355425030023718 Q05022 0.07237870991230011 0.048865973949432366 41.974812344112074 30.0 0.0 no 10740 chrXIII_728153r 28322 essential YMR229C 2948 + ACCATCAGAATTAAAATCTA P|984|R P|984|L P|984|A P|984|S RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 -0.9245310180114152 Q05022 0.20480138063430786 0.1100262701511383 0.29482030868530273 0.5170313119888306 35.029203444633715 25.0 0.0 no 10741 chrXIII_728357r 28325 essential YMR229C 2744 + GGCAAATTTGCATGGCAGAG A|916|G A|916|V RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 -0.22669736251943265 Q05022 0.1877499222755432 0.02913535386323929 47.619898891719856 50.0 0.0 no 10742 chrXIII_728574 28328 essential YMR229C 2530 - TCTTAATAAATAGACGGTAA R|850|T R|850|K RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 -0.2184981413833829 Q05022 0.22599028050899506 0.9379333257675172 32.870206130258225 25.0 0.0 no 10743 chrXIII_728635 28329 essential YMR229C 2469 - CTACTATCAACAGCGTAACT S|829|T S|829|N RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 0.08548019693634831 Q05022 0.34640297293663025 0.4348703622817993 42.477531916902315 40.0 0.0 no 10744 chrXIII_728789r 28332 essential YMR229C 2312 + TCTGATTAAAGACGCTAAAA L|772|V silent|CTG>TTG|L|772 RRP5 Ribosomal RNA Processing 1729.0 0 1 0 0 -0.09727266544941778 Q05022 0.0 34.472691487503646 30.0 0.0 no 10745 chrXIII_728910r 28334 essential YMR229C 2191 + ATTCCAGAATTGAACAAAAT S|732|C S|732|F silent|TCC>TCG|S|732 silent|TCC>TCT|S|732 RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 -0.19536329001354466 Q05022 0.012578752823174 0.005062313750386238 33.86963287268929 25.0 0.0 no 10746 chrXIII_728956 28336 essential YMR229C 2148 - ACACCACGCAAGCCAACATC G|722|A G|722|D V|723|L V|723|I RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 0.18267339866123766 Q05022 0.0 0.0 0.041750285774469376 0.2923586070537567 51.08544820827302 55.00000000000001 0.0 no 10747 chrXIII_728982 28338 essential YMR229C 2122 - TTCAACAATAACAGAATCTT E|714|Q E|714|K V|713|L V|713|I RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 -0.623283894659599 Q05022 0.027076046913862232 0.121997132897377 0.04098911210894585 0.2781513929367065 33.717872561833765 25.0 0.0 no 10748 chrXIII_729022 28339 essential YMR229C 2082 - ACAGTAATGATTGTTCTGCC V|701|L V|701|I RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 -0.9665720018536642 Q05022 0.12966696918010712 0.08180481940507889 46.06918245279519 40.0 0.0 no 10749 chrXIII_729053 28340 essential YMR229C 2051 - TTTCAATGGTATCTTTTTGT E|690|Q E|690|K RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 0.9823143717474256 Q05022 0.3990766704082489 0.5865928530693054 41.03118630989081 25.0 0.0 no 10750 chrXIII_729199 28345 essential YMR229C 1905 - ACTTCTGAGATCTCAGAATT V|642|L V|642|I E|641|Q E|641|K RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 -1.0055324575370423 Q05022 0.18188072741031647 0.2575528621673584 0.0 0.0 42.00598789275853 35.0 0.0 no 10751 chrXIII_729262r 28346 essential YMR229C 1839 + ATTCAAGTTTTCAAACCAAA Q|615|E Q|615|* RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 0.0005545089298888972 Q05022 1.0 36.15560782004576 25.0 0.0 no 10752 chrXIII_729448 28347 essential YMR229C 1656 - CCTATCTTGAACTTCCTTTC G|559|R G|559|S K|557|N silent|AAG>AAA|K|557 RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 -0.545784185407195 Q05022 0.01010032556951046 0.036400429904460914 0.018980065360665318 47.80509436404026 40.0 0.0 no 10753 chrXIII_729448r 28348 essential YMR229C 1653 + CCAGAAAGGAAGTTCAAGAT P|552|R P|552|L RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 -0.029431079581427988 Q05022 0.0 0.0 39.90531834144508 40.0 0.0 no 10754 chrXIII_729543 28350 essential YMR229C 1561 - TTCAATACCTGAACTAGAGA E|527|Q E|527|K RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 0.01825924411143069 Q05022 0.5894589424133301 0.9272372722625732 39.89566803775949 35.0 0.0 no 10755 chrXIII_729562 28351 essential YMR229C 1542 - ACGGAAGTTATTTCACAACT V|521|L V|521|I RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 -0.09727856496064424 Q05022 0.1897826194763184 0.2220553159713745 40.761265358445776 35.0 0.0 no 10756 chrXIII_729614 28352 essential YMR229C 1490 - TTCTTAGATACTTTAATTTT R|503|T R|503|K RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 -0.3787108192361177 Q05022 0.1117880791425705 0.5069635510444641 33.86819665653093 15.0 0.0 no 10757 chrXIII_729668 28353 essential YMR229C 1436 - CATCAACAGGGCTATAACCA D|485|H D|485|N V|484|L V|484|I RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 -0.5058377102579836 Q05022 0.0 0.0 0.32166510820388794 0.6251580715179443 46.273560110309525 45.0 0.0 no 10758 chrXIII_729693r 28355 essential YMR229C 1408 + ATTCAGAAAATTTAAGTTCC S|471|* S|471|L RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 -0.7216457529777851 Q05022 0.13228373229503632 34.94820199684756 25.0 0.0 no 10759 chrXIII_729815 28357 essential YMR229C 1289 - ATTCAAATGTGTAGCCGATA E|436|Q E|436|K RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 0.23804099325925776 Q05022 0.051779359579086304 0.04990635067224503 42.73577923970754 35.0 0.0 no 10760 chrXIII_729850r 28359 essential YMR229C 1251 + GACGCTTTGAGATCTACTGA D|418|E silent|GAC>GAT|D|418 A|419|G A|419|V RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 0.2808286961352928 Q05022 0.8495658636093141 0.3473050594329834 0.2942870259284973 46.3024650519759 45.0 0.0 no 10761 chrXIII_729871 28360 essential YMR229C 1233 - TCTTCTAGTTTTAAAATGTG D|418|H D|418|N E|417|Q E|417|K RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 0.5152819281055219 Q05022 0.17528985440731049 1.0 0.5829170346260071 0.909986972808838 35.11025173754501 25.0 0.0 no 10762 chrXIII_729932 28361 essential YMR229C 1172 - TTTCTAAACAAGCAATAATT E|397|Q E|397|K RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 -1.0936571409449614 Q05022 0.6420612335205078 0.980283498764038 32.01767419874733 20.0 0.0 no 10763 chrXIII_730111r 28364 essential YMR229C 990 + TCAATTGATGCCATTATCCC S|331|* S|331|L RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 0.4166078165108248 Q05022 0.006221567280590534 48.45710783108984 40.0 0.0 no 10764 chrXIII_730371 28371 essential YMR229C 733 - TTCATCTGCGTATATGTTGA E|251|Q E|251|K D|250|H D|250|N RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 -0.12994468475618576 Q05022 0.15811996161937714 0.18796129524707794 0.0594070740044117 0.2305769771337509 44.8624359662004 35.0 0.0 no 10765 chrXIII_730378 28372 essential YMR229C 726 - GCGTATATGTTGACGGATGA A|249|P A|249|T RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 0.506951144904306 Q05022 0.2135254591703415 0.5643840432167053 45.93173069483242 45.0 0.0 no 10766 chrXIII_730693r 28374 essential YMR229C 408 + ACATTCACAGACGGAATTTC T|137|R T|137|I F|138|L silent|TTC>TTT|F|138 RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 -0.07405278417429599 Q05022 0.0262546855956316 0.01574622094631195 1.0 41.91307002343143 40.0 0.0 no 10767 chrXIII_730661 28376 essential YMR229C 443 - ATTCTTCTGAGATATGTGTT E|154|Q E|154|K E|153|Q E|153|K RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 -1.0231885191446006 Q05022 0.5386269092559814 0.7273839712142944 0.5345224142074585 0.8075275421142578 42.36406824721233 30.0 0.0 no 10768 chrXIII_730960 28379 essential YMR229C 144 - GCAACTTGTTTCAGTTCTAA A|55|P A|55|T V|54|L V|54|I RRP5 Ribosomal RNA Processing 1729.0 0 0 0 0 -0.8893321764715343 Q05022 0.057015236467123025 0.07388514280319214 0.07745135575532912 0.8992992043495178 44.08120671568878 35.0 0.0 no 10769 chrXIII_741909r 28382 essential YMR235C 804 + GACTGTCTTTTGAAAACTGC D|269|E silent|GAC>GAT|D|269 L|271|V L|271|F RNA1 rapid cessation of net RNA accumulation 407.0 0 0 0 0 0.19799842067056656 P11745 0.0 0.03298085182905197 0.0455455482006073 1.5235999822616575 0.08219999819993973 41.403875624091135 40.0 0.0 no 10770 chrXIII_741953 28383 essential YMR235C 763 - ACTATCCTTCCATGTAGGCA S|261|T S|261|N D|260|H D|260|N RNA1 rapid cessation of net RNA accumulation 407.0 0 0 0 0 -0.2164397621513484 P11745 0.3793090283870697 0.2521021068096161 0.03302562609314918 0.229484498500824 53.672198287141434 45.0 0.0 no 10771 chrXIII_742098r 28386 essential YMR235C 615 + GTCGTAAAGCTGTACCAAAA silent|GTC>GTG|V|206 silent|GTC>GTT|V|206 RNA1 rapid cessation of net RNA accumulation 407.0 0 0 0 0 -0.6596410085017952 P11745 41.6888523371282 40.0 0.0 no 10772 chrXIII_742149r 28389 essential YMR235C 564 + TCCGCAGTCTACTTAGCTCT silent|TCC>TCG|S|189 silent|TCC>TCT|S|189 S|189|C S|189|F RNA1 rapid cessation of net RNA accumulation 407.0 0 0 0 0 0.5987423324963136 P11745 0.0 0.0 56.07177501621528 50.0 0.0 no 10773 chrXIII_742266 28390 essential YMR235C 450 - CCAATCCTTTCACCAGCAAA G|157|R G|157|S R|155|S silent|AGG>AGA|R|155 RNA1 rapid cessation of net RNA accumulation 407.0 0 0 0 0 -0.4348128558906147 P11745 0.009177140891551971 0.14486916363239288 0.14838412404060364 49.451141152985365 45.0 0.0 no 10774 chrXIII_742290r 28391 essential YMR235C 423 + ATCTTAAGTAACAATGGTAT I|142|M silent|ATC>ATT|I|142 RNA1 rapid cessation of net RNA accumulation 407.0 0 0 0 0 0.034128917077935306 P11745 0.09557748585939407 0.05260000005364418 35.40750997898203 25.0 0.0 no 10775 chrXIII_742291r 28392 essential YMR235C 422 + GATCTTAAGTAACAATGGTA I|142|M silent|ATC>ATT|I|142 RNA1 rapid cessation of net RNA accumulation 407.0 0 0 0 0 0.2835011546374616 P11745 0.09557748585939407 0.05260000005364418 36.593771137540564 30.0 0.0 no 10776 chrXIII_742310 28393 essential YMR235C 406 - GATCAAATGTTTGATATTCA L|141|F silent|TTG>TTA|L|141 RNA1 rapid cessation of net RNA accumulation 407.0 0 0 0 0 -0.3254764689499605 P11745 0.10658842325210573 35.980674189207214 25.0 0.0 no 10777 chrXIII_742373r 28394 essential YMR235C 340 + ACCTTTCTGATAATGCGTTT L|115|V L|115|F N|114|K silent|AAC>AAT|N|114 RNA1 rapid cessation of net RNA accumulation 407.0 0 0 0 0 -0.2350070289040566 P11745 0.016596170142292976 0.0868198499083519 0.0943714827299118 45.673834781093724 35.0 0.0 no 10778 chrXIII_742405r 28395 essential YMR235C 308 + TCTGTTGAAATGTCCTCACT L|104|V silent|CTG>TTG|L|104 RNA1 rapid cessation of net RNA accumulation 407.0 0 0 0 0 0.6703203697952197 P11745 0.2254330962896347 46.734622259076396 40.0 0.0 no 10779 chrXIII_742468r 28396 essential YMR235C 245 + TGACTTATACACTTCGAGGT D|83|E silent|GAC>GAT|D|83 RNA1 rapid cessation of net RNA accumulation 407.0 0 0 0 0 0.8684570205399635 P11745 0.0 44.540889679244 40.0 0.0 no 10780 chrXIII_742472r 28397 essential YMR235C 241 + TTGCTGACTTATACACTTCG A|82|G A|82|V RNA1 rapid cessation of net RNA accumulation 407.0 0 0 0 0 1.220206110543821 P11745 0.12422604858875275 0.052055135369300835 -0.33399999141693115 2.771199941635132 44.081781209484575 40.0 0.0 no 10781 chrXIII_742516r 28399 essential YMR235C 197 + CGCTGAAAATACACAGGTCA A|67|G A|67|V RNA1 rapid cessation of net RNA accumulation 407.0 0 0 0 0 0.4918597987818861 P11745 0.3770730793476105 0.30739280581474304 -0.08219999819993973 4.610799789428711 42.94240603868133 45.0 0.0 no 10782 chrXIII_742522r 28400 essential YMR235C 191 + ATGCATCGCTGAAAATACAC C|65|W silent|TGC>TGT|C|65 I|66|M silent|ATC>ATT|I|66 RNA1 rapid cessation of net RNA accumulation 407.0 0 0 0 0 1.152731813160458 P11745 0.2051357924938202 0.03683234751224518 -2.566800117492676 40.54478273290397 40.0 0.0 no 10783 chrXIII_742583r 28402 essential YMR235C 130 + GTACCAAATTAGACCTTTCA T|45|S T|45|I silent|ACC>ACG|T|45 silent|ACC>ACT|T|45 RNA1 rapid cessation of net RNA accumulation 407.0 0 0 0 0 0.08277654707239993 P11745 0.3855990767478943 0.12178879231214525 43.688290175604095 35.0 0.0 no 10784 chrXIII_742612 28403 essential YMR235C 104 - TCAAAGCTGCCAATTCTTCC L|41|F silent|TTG>TTA|L|41 A|40|P A|40|T RNA1 rapid cessation of net RNA accumulation 407.0 0 0 0 0 -0.18707656280163448 P11745 0.4536406397819519 0.2337442487478256 0.4563324749469757 -0.656000018119812 7.370999813079834 1.6782000064849854 49.28059960266215 45.0 0.0 no 10785 chrXIII_742617 28404 essential YMR235C 99 - GCTGCCAATTCTTCCAGGTA A|40|P A|40|T A|39|P A|39|T RNA1 rapid cessation of net RNA accumulation 407.0 0 0 0 0 -0.5260928574387213 P11745 0.2337442487478256 0.4563324749469757 0.27286338806152344 0.5549710392951965 7.370999813079834 1.6782000064849854 6.271200180053711 0.3711999952793121 56.10052882440584 50.0 0.0 no 10786 chrXIII_742676r 28405 essential YMR235C 37 + AACAAGTTTACTCCATCTCT Q|14|E Q|14|* RNA1 rapid cessation of net RNA accumulation 407.0 0 0 0 0 0.3092387918651786 P11745 0.3643949329853058 44.50115631319829 35.0 0.0 no 10787 chrXIII_742692 28406 essential YMR235C 24 - ACTTGTTCTTCCTCGTGCTG V|15|L V|15|I RNA1 rapid cessation of net RNA accumulation 407.0 0 0 0 0 0.5696301848955188 P11745 0.5437308549880981 1.0 54.99128007959109 50.0 0.0 no 10788 chrXIII_743096 28411 essential YMR236W 125 + ACAGTCGATTCATCAATATG Q|43|E Q|43|* S|44|W S|44|L TAF9 TATA binding protein-Associated Factor 157.0 0 0 0 0 -0.4211201901835165 Q05027 0.9590039849281312 0.9288619756698608 0.9298099875450134 0.12567035853862762 0.0006290616001933812 0.00429912842810154 39.79749687148063 35.0 1.0 no 10789 chrXIII_743120 28412 essential YMR236W 149 + CCAAGTACCGCTACAATTGA Q|51|E Q|51|* TAF9 TATA binding protein-Associated Factor 157.0 0 0 0 0 1.3117100781946176 Q05027 0.9590039849281312 0.016250681132078167 46.811516406221024 45.0 1.0 no 10790 chrXIII_743221r 28417 essential YMR236W 253 - TTCTACTCCTAATCCACTGC E|91|Q E|91|K V|90|L V|90|I TAF9 TATA binding protein-Associated Factor 157.0 0 0 0 0 -1.4272841264284477 Q05027 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.4923571050167084 0.6728907227516174 0.5333040356636047 0.5984355211257935 50.69819728633286 45.0 1.0 no 10791 chrXIII_743273 28418 essential YMR236W 302 + ACAATACCAATTTAAGCCTA Q|102|E Q|102|* Y|103|* silent|TAC>TAT|Y|103 TAF9 TATA binding protein-Associated Factor 157.0 0 0 0 0 0.14967482480074715 Q05027 0.9590039849281312 0.21636605262756348 40.618741334297226 30.0 1.0 no 10792 chrXIII_743298r 28419 essential YMR236W 330 - AACTGTAACATGAGCTCCTT Q|116|H silent|CAG>CAA|Q|116 TAF9 TATA binding protein-Associated Factor 157.0 0 0 0 0 -0.18377667324065053 Q05027 0.9570760130882264 0.005933064501732589 45.79754449860491 40.0 1.0 no 10793 chrXIII_748624r 28421 essential YMR239C 1031 + GCTTGCCAAACCTGTCATTG L|345|V L|345|F A|346|G A|346|V RNT1 RNase Three 471.0 0 0 0 0 -0.06387856893800839 Q02555 0.0 0.0 0.10844913125038147 0.3521184623241425 3.604640007019043 2.6070199012756348 1.8691999912261963 1.8882199525833132 51.610840296840884 50.0 0.0 no 10794 chrXIII_748874 28425 essential YMR239C 784 - TAACTGACCCTCGCTGTAAT Q|267|H silent|CAG>CAA|Q|267 RNT1 RNase Three 471.0 0 0 0 0 0.22551807947799354 Q02555 0.017880050465464592 0.9317200183868408 0.7647600173950195 48.41301342519677 45.0 0.0 no 10795 chrXIII_748875 28426 essential YMR239C 783 - AACTGACCCTCGCTGTAATC Q|267|H silent|CAG>CAA|Q|267 G|266|A G|266|D RNT1 RNase Three 471.0 0 0 0 0 -0.26835491610543194 Q02555 0.017880050465464592 0.0 0.0 0.9317200183868408 -0.631600022315979 -1.0041999816894531 0.7647600173950195 49.93844007675051 50.0 0.0 no 10796 chrXIII_749058 28428 essential YMR239C 600 - TCTTGAATCTCTGGTAATTT D|207|H D|207|N RNT1 RNase Three 471.0 0 0 0 0 0.6696129646677274 Q02555 0.020148951560258862 1.0 3.774440050125122 2.9088799953460693 40.80759993883618 30.0 0.0 no 10797 chrXIII_749100 28429 essential YMR239C 558 - ACGATATCACCAGCCTTTGT V|193|L V|193|I RNT1 RNase Three 471.0 0 0 0 0 0.07567032672428464 Q02555 0.3129670321941376 0.19691452383995056 51.68419734517295 45.0 0.0 no 10798 chrXIII_749374r 28430 essential YMR239C 281 + ATCACGTTATCAATTAAAAC S|95|* S|95|L R|96|G R|96|C RNT1 RNase Three 471.0 0 0 0 0 -0.4613394789325282 Q02555 0.7341448664665222 0.0 0.0 0.09570000320672988 0.9580399990081788 0.4575400054454804 32.84850796661266 25.0 0.0 no 10799 chrXIII_749109r 28431 essential YMR239C 546 + AGCTATGACCCAACAAAGGC S|183|R silent|AGC>AGT|S|183 RNT1 RNase Three 471.0 0 0 0 0 0.5076627105633498 Q02555 0.4076296985149384 47.88652234085021 50.0 0.0 no 10800 chrXIII_749420 28432 essential YMR239C 238 - CACTCTATCTTGATTGTTAA V|86|L V|86|M R|85|T R|85|K RNT1 RNase Three 471.0 0 0 0 0 0.5380330266704048 Q02555 0.5452335476875305 0.06862469762563705 0.07710637897253036 1.0 0.2319400012493133 -0.01252000033855438 0.22849999368190765 -0.2642599940299988 40.13431140141051 30.0 0.0 no 10801 chrXIII_749623 28433 essential YMR239C 35 - TATCTAGTTTATTATCATTC D|18|H D|18|N RNT1 RNase Three 471.0 0 0 0 0 -0.1284348171823392 Q02555 0.09510818123817444 0.3636822700500488 35.90625878154782 20.0 0.0 no 10802 chrXIII_749624 28434 essential YMR239C 34 - ATCTAGTTTATTATCATTCT D|18|H D|18|N RNT1 RNase Three 471.0 0 0 0 0 0.535220163948914 Q02555 0.09510818123817444 0.3636822700500488 38.521097248800174 20.0 0.0 no 10803 chrXIII_749445 28435 essential YMR239C 213 - TCATTGTAAGCTACCAAATT E|78|Q E|78|K RNT1 RNase Three 471.0 0 0 0 0 0.27909249731701385 Q02555 0.3335445523262024 0.03888392820954323 -0.04041999951004982 0.04839999973773956 40.20695823020702 30.0 0.0 no 10804 chrXIII_750305r 28438 essential YMR240C 913 + CCGAAGGTCAACTACCACCA silent|CCC>CCG|P|305 silent|CCC>CCT|P|305 CUS1 Cold sensitive U2 snRNA Suppressor 436.0 0 0 0 0 0.93161031401077 Q02554 51.86059187745366 55.00000000000001 0.0 no 10805 chrXIII_750321r 28439 essential YMR240C 897 + GCCATAATGAATTTACCCGA silent|GCC>GCG|A|300 silent|GCC>GCT|A|300 A|300|G A|300|V CUS1 Cold sensitive U2 snRNA Suppressor 436.0 0 0 0 0 0.17775334494032635 Q02554 0.30700406432151794 0.2296993583440781 45.981620407878275 40.0 0.0 no 10806 chrXIII_750441r 28445 essential YMR240C 777 + CCTGACCATTTGTTATGCTT P|260|R P|260|L D|261|E silent|GAC>GAT|D|261 CUS1 Cold sensitive U2 snRNA Suppressor 436.0 0 0 0 0 -0.02452216639840639 Q02554 0.0 0.0 0.7600878477096558 50.13471899273503 40.0 0.0 no 10807 chrXIII_750503 28446 essential YMR240C 718 - CTTCTTGTAATCCAAATCCA K|245|N silent|AAG>AAA|K|245 CUS1 Cold sensitive U2 snRNA Suppressor 436.0 0 0 0 0 0.5427813978212193 Q02554 0.01925240084528923 44.06264297343022 35.0 0.0 no 10808 chrXIII_750582 28453 essential YMR240C 639 - TGACCATCCAGTCCGCTTTG G|219|A G|219|D G|219|R G|219|S CUS1 Cold sensitive U2 snRNA Suppressor 436.0 0 0 0 0 0.6276318893592305 Q02554 0.7479754090309143 0.652432918548584 0.5291885137557983 0.7069000005722046 56.431513575213955 55.00000000000001 0.0 no 10809 chrXIII_750697 28458 essential YMR240C 524 - ATTCCTTCTTGGACTGCCAG E|181|Q E|181|K K|180|N silent|AAG>AAA|K|180 CUS1 Cold sensitive U2 snRNA Suppressor 436.0 0 0 0 0 -0.2000226184901654 Q02554 0.03653869405388832 0.0293608233332634 0.02442512847483158 54.41231678884333 50.0 0.0 no 10810 chrXIII_750700r 28459 essential YMR240C 518 + AAGCCACTGGCAGTCCAAGA S|174|R silent|AGC>AGT|S|174 H|175|D H|175|Y CUS1 Cold sensitive U2 snRNA Suppressor 436.0 0 0 0 0 -0.5541999015512006 Q02554 0.4957497715950012 0.0 0.0 54.46646993711829 55.00000000000001 0.0 no 10811 chrXIII_750713r 28462 essential YMR240C 505 + TCATTCCTGTTCCAAGCCAC silent|GTC>GTG|V|169 silent|GTC>GTT|V|169 P|171|A P|171|S CUS1 Cold sensitive U2 snRNA Suppressor 436.0 0 0 0 0 0.831217505815928 Q02554 0.08554720878601074 0.061040926724672324 55.181625600054474 50.0 0.0 no 10812 chrXIII_750789 28463 essential YMR240C 432 - TCGTACCATTCTATAATTTG D|151|H D|151|N W|149|C W|149|* CUS1 Cold sensitive U2 snRNA Suppressor 436.0 0 0 0 0 0.8465964116560059 Q02554 0.0 0.0 0.0 40.07714596694308 30.0 0.0 no 10813 chrXIII_750881 28464 essential YMR240C 340 - ATGCTCCTCAATACCATCCG E|119|D silent|GAG>GAA|E|119 E|119|Q E|119|K CUS1 Cold sensitive U2 snRNA Suppressor 436.0 0 1 0 0 -1.7623371104946717e-06 Q02554 0.5131204724311829 0.4851425886154175 0.7881897091865541 52.64654480697686 50.0 0.0 no 10814 chrXIII_750882 28465 essential YMR240C 339 - TGCTCCTCAATACCATCCGA E|119|D silent|GAG>GAA|E|119 E|119|Q E|119|K CUS1 Cold sensitive U2 snRNA Suppressor 436.0 0 1 0 0 0.09730016026696564 Q02554 0.5131204724311829 0.4851425886154175 0.7881897091865541 53.79859040497768 50.0 0.0 no 10815 chrXIII_750913r 28467 essential YMR240C 305 + GCATACAGCAGAAGATGAAT H|103|D H|103|Y T|104|R T|104|I CUS1 Cold sensitive U2 snRNA Suppressor 436.0 0 1 0 0 0.6231287482550342 Q02554 0.2156359851360321 1.0 0.5260113477706909 0.1908462792634964 41.20930682840475 40.0 0.0 no 10816 chrXIII_750987 28468 essential YMR240C 234 - TCATCTTTCGTGATTTCCTT E|85|Q E|85|K D|84|H D|84|N CUS1 Cold sensitive U2 snRNA Suppressor 436.0 0 0 0 0 -0.7230959778505341 Q02554 0.4863965213298798 0.3497593700885773 0.0595349557697773 0.19622400403022766 48.363318998877325 35.0 0.0 no 10817 chrXIII_751180 28472 essential YMR240C 41 - CCACAGACGCATTCTTATTT V|20|L V|20|M silent|GTG>GTC|V|20 silent|GTG>GTA|V|20 CUS1 Cold sensitive U2 snRNA Suppressor 436.0 0 0 0 0 1.1750434797049214 Q02554 0.3734332919120789 0.08004854619503021 47.259594848071565 40.0 0.0 no 10818 chrXIII_751180r 28473 essential YMR240C 38 + CCAAAATAAGAATGCGTCTG Q|14|E Q|14|* CUS1 Cold sensitive U2 snRNA Suppressor 436.0 0 0 0 0 -0.5452033837246428 Q02554 1.0 38.55364821124846 40.0 0.0 no 10819 chrXIII_751208 28474 essential YMR240C 13 - TCCGGAACGCTTCCTACTTT G|11|R G|11|R G|11|A G|11|E CUS1 Cold sensitive U2 snRNA Suppressor 436.0 0 0 0 0 -0.4305342547385857 Q02554 0.3009769022464752 0.3009769022464752 1.0 0.5398156046867371 53.00556003033057 50.0 0.0 no 10820 chrXIII_789490 28476 essential YMR260C 330 - TCATTAATTTTGGCGTTTTC E|117|Q E|117|K TIF11 Translation Initiation Factor 153.0 0 0 0 0 0.2739101585577661 P38912 0.07894830405712128 0.02324497513473034 42.01907790135147 30.0 0.0 no 10821 chrXIII_789519 28477 essential YMR260C 301 - ACCTTGGTTTTTCAGTGTTC G|107|R G|107|S G|107|A G|107|D TIF11 Translation Initiation Factor 153.0 0 1 0 0 0.8374990311376251 P38912 0.015389058738946916 0.0447264239192009 0.02231218852102756 0.12120391428470613 50.83968501662206 40.0 0.0 no 10822 chrXIII_789542 28479 essential YMR260C 278 - CTTCATCTAAATTATATTTG E|99|Q E|99|K D|98|H D|98|N TIF11 Translation Initiation Factor 153.0 0 1 0 0 -0.5098680979432684 P38912 0.04511215537786484 0.0041263522580266 0.07619952410459517 0.1757253110408783 32.613100697323944 20.0 0.0 no 10823 chrXIII_789566 28480 essential YMR260C 254 - CAACATCACATTGGTCATCT V|91|L V|91|I D|90|H D|90|N TIF11 Translation Initiation Factor 153.0 0 1 0 0 -0.2608370052299305 P38912 0.017758799716830254 0.5777696371078491 0.0018864377634599805 0.008599067106842995 45.101325016762765 40.0 0.0 no 10824 chrXIII_789579 28481 essential YMR260C 241 - GTCATCTTGGAAATCTCTTA D|87|H D|87|N D|86|H D|86|N TIF11 Translation Initiation Factor 153.0 0 0 0 0 0.6335461829987744 P38912 0.2159297317266464 1.0 0.015603287145495416 0.27443635463714605 42.89634811284907 35.0 0.0 no 10825 chrXIII_789641 28482 essential YMR260C 179 - TTCTTAACTTACCTCTAATA R|66|T R|66|K TIF11 Translation Initiation Factor 153.0 0 0 0 0 -0.15626385406671425 P38912 0.1056213229894638 0.20127293467521667 38.77376424109128 25.0 0.0 no 10826 chrXIII_789642 28483 essential YMR260C 178 - TCTTAACTTACCTCTAATAT R|66|T R|66|K K|64|N silent|AAG>AAA|K|64 TIF11 Translation Initiation Factor 153.0 0 0 0 0 0.6510447055671538 P38912 0.1056213229894638 0.20127293467521667 0.009487291797995569 38.53295847641681 25.0 0.0 no 10827 chrXIII_789702 28485 essential YMR260C 118 - TCTTCCATTACCCAACATCT R|46|T R|46|K G|45|A G|45|E TIF11 Translation Initiation Factor 153.0 0 0 0 0 -0.4575747969167509 P38912 0.0428134985268116 0.0784032866358757 0.2610458433628082 0.022650819271802902 50.44390981760501 40.0 0.0 no 10828 chrXIII_803526 28489 essential YMR268C 677 - CCTCAAAAGATTCCCTCAGA E|232|Q E|232|K E|232|D silent|GAG>GAA|E|232 PRP24 Pre-mRNA Processing 444.0 0 0 0 0 0.3984124292330151 P49960 0.539947509765625 0.8469849824905396 0.574346125125885 -0.016498999670147896 -0.16883200407028198 0.9094990491867064 47.985442414629524 45.0 0.0 no 10829 chrXIII_803538r 28491 essential YMR268C 662 + GCTCGACGAAAACCTTCTGA silent|CTC>CTG|L|222 silent|CTC>CTT|L|222 L|222|V L|222|F PRP24 Pre-mRNA Processing 444.0 0 0 0 0 0.17705040118778592 P49960 0.6645093560218811 0.10054133087396623 3.6657328605651855 3.821049213409424 46.574085530546206 50.0 0.0 no 10830 chrXIII_803553 28492 essential YMR268C 650 - CGTCGAGCAATTCTGTACTT D|223|H D|223|N PRP24 Pre-mRNA Processing 444.0 0 0 0 0 1.15666912058645 P49960 0.18053166568279266 1.0 4.29951810836792 2.810338020324707 47.412012208716824 45.0 0.0 no 10831 chrXIII_803597r 28495 essential YMR268C 603 + ACCGATTCTGCCACACTAGA silent|ACC>ACG|T|202 silent|ACC>ACT|T|202 T|202|S T|202|I PRP24 Pre-mRNA Processing 444.0 0 0 0 0 -0.33722428436095364 P49960 0.7290645241737366 0.012573856860399244 0.02985999919474125 -0.1137399971485138 52.21859447238897 50.0 0.0 no 10832 chrXIII_803634r 28496 essential YMR268C 566 + TACTAAAGTTTCCAATCCGC T|190|S T|190|I PRP24 Pre-mRNA Processing 444.0 0 0 0 0 -0.6890027968865977 P49960 0.07055342197418213 0.5280665159225464 1.6841490268707275 0.20692497491836548 44.76210806966469 40.0 0.0 no 10833 chrXIII_803752 28498 essential YMR268C 451 - GCTTGTATTGAATCGTAAAC S|157|T S|157|N PRP24 Pre-mRNA Processing 444.0 0 0 0 0 1.1990691463788306 P49960 0.057513944804668427 1.0 0.433118999004364 0.41561898589134216 38.699528485263045 35.0 0.0 no 10834 chrXIII_803908 28502 essential YMR268C 295 - ACCTACAACTTTGTGTGTTT G|105|R G|105|S G|105|A G|105|D PRP24 Pre-mRNA Processing 444.0 0 0 0 0 0.20389370355587189 P49960 0.0 0.0 0.0 0.0 4.455793857574463 4.3451128005981445 4.1353936195373535 4.4355950355529785 45.91863991815433 35.0 0.0 no 10835 chrXIII_803956r 28505 essential YMR268C 244 + TTGCACGTATTGAATTTGCC A|83|G A|83|V R|84|G R|84|C PRP24 Pre-mRNA Processing 444.0 0 0 0 0 0.15782867073394952 P49960 0.18509380519390106 0.01869331859052181 0.009064587764441969 0.0012140473118051887 1.9023000001907349 -0.7986600399017334 3.9409570693969727 1.7341569662094116 45.97617009758454 40.0 0.0 no 10836 chrXIII_804004 28506 essential YMR268C 199 - CGCAACATCAACGTGTATAA A|73|P A|73|T V|72|L V|72|I PRP24 Pre-mRNA Processing 444.0 0 0 0 0 -0.40767093058381176 P49960 0.083809033036232 0.3282429277896881 0.2165367156267166 0.30942806601524353 2.0387499332427983 -0.6026580333709717 0.9291709661483764 0.09333600103855133 40.942089217513 40.0 0.0 no 10837 chrXIII_804161 28509 essential YMR268C 42 - GCTGGTGATCCTTCATCCAA A|21|P A|21|T PRP24 Pre-mRNA Processing 444.0 0 1 0 0 0.4248766273107317 P49960 0.330838143825531 0.6723053455352783 54.74514792386663 50.0 0.0 no 10838 chrXIII_805628 28511 essential YMR270C 776 - TTCTCTTTTTATACTTTTCT R|265|T R|265|K K|264|N silent|AAG>AAA|K|264 RRN9 Regulation of RNA polymerase I 365.0 0 0 0 0 0.8396484373824175 P53437 0.3486392796039581 1.0 0.03281344845890999 40.50874691847474 20.0 0.0 no 10839 chrXIII_805747 28512 essential YMR270C 657 - ATTCGTCGATTGGCCTGCAT R|225|P R|225|Q R|224|P R|224|Q RRN9 Regulation of RNA polymerase I 365.0 0 0 0 0 -0.028119432818019763 P53437 0.14438970386981964 0.3971941769123077 0.04047929123044014 0.26603636145591736 54.22691869505542 50.0 0.0 no 10840 chrXIII_805821 28513 essential YMR270C 583 - TACATCGAATTCGTTCTCTT V|201|L V|201|I D|200|H D|200|N RRN9 Regulation of RNA polymerase I 365.0 0 0 0 0 0.3455074536380347 P53437 0.7128481864929199 1.0 0.10987450927495956 0.5430790185928345 43.465204136640644 35.0 0.0 no 10841 chrXIII_805860r 28514 essential YMR270C 541 + AACTGGACAGCTTATTCGAA L|182|V silent|CTG>TTG|L|182 RRN9 Regulation of RNA polymerase I 365.0 0 0 0 0 0.3986384818324488 P53437 0.023154182359576225 42.82335857306328 40.0 0.0 no 10842 chrXIII_805928 28517 essential YMR270C 476 - CCACATCTAGAGTTACATCA V|165|L V|165|M silent|GTG>GTC|V|165 silent|GTG>GTA|V|165 RRN9 Regulation of RNA polymerase I 365.0 0 0 0 0 -0.2029610225940919 P53437 0.05930731073021889 0.011142744682729244 46.056580639133976 40.0 0.0 no 10843 chrXIII_805896r 28518 essential YMR270C 505 + ACATTCCAAACGAAATATCC N|169|K silent|AAC>AAT|N|169 P|171|A P|171|S RRN9 Regulation of RNA polymerase I 365.0 0 0 0 0 -0.6551437771819184 P53437 0.2016850858926773 0.0 0.0 39.2405207850241 35.0 0.0 no 10844 chrXIII_805995 28519 essential YMR270C 409 - CTCAACCCTCATCATATCAG E|143|Q E|143|K V|142|L V|142|I RRN9 Regulation of RNA polymerase I 365.0 0 0 0 0 -2.4449465154517034 P53437 0.0 0.0 1.0 0.8497664928436279 48.13613424140698 45.0 0.0 yes 10845 chrXIII_806001r 28520 essential YMR270C 400 + TGCACGCCTCTGATATGATG H|135|D H|135|Y H|135|Q silent|CAC>CAT|H|135 RRN9 Regulation of RNA polymerase I 365.0 0 0 0 0 -0.12064463283626198 P53437 0.0 0.0 0.0 49.61046404624671 50.0 0.0 no 10846 chrXIII_806113 28526 essential YMR270C 291 - TCAATAATTGTATTGGGATT D|104|H D|104|N RRN9 Regulation of RNA polymerase I 365.0 0 0 0 0 -0.046610129220741266 P53437 0.011579341255128384 0.16050225496292114 36.785331979210355 25.0 0.0 no 10847 chrXIII_806141 28527 essential YMR270C 263 - TCGTCCAGTTATCCTTAATT silent|ACG>ACC|T|94 silent|ACG>ACA|T|94 W|93|C W|93|* RRN9 Regulation of RNA polymerase I 365.0 0 0 0 0 -0.97331222233797 P53437 0.0 47.504592352276354 35.0 0.0 no 10848 chrXIII_806142 28528 essential YMR270C 262 - CGTCCAGTTATCCTTAATTT W|93|C W|93|* W|93|S W|93|* RRN9 Regulation of RNA polymerase I 365.0 0 0 0 0 -1.3105865775124088 P53437 0.0 0.0 46.737993874857466 35.0 0.0 no 10849 chrXIII_806319 28530 essential YMR270C 85 - CTCTTTATCAGCGGTTGTAG E|35|Q E|35|K RRN9 Regulation of RNA polymerase I 365.0 0 0 0 0 -0.4290789408934033 P53437 0.5567579865455627 0.5919753909111023 48.507578104996746 45.0 0.0 no 10850 chrXIII_806353 28531 essential YMR270C 51 - CCTCGTATAATATCTTCGAT R|23|P R|23|Q G|24|R G|24|R RRN9 Regulation of RNA polymerase I 365.0 0 0 0 0 0.2918868635516774 P53437 0.5050725340843201 0.5050725340843201 42.99199275552763 35.0 0.0 no 10851 chrXIII_806353r 28532 essential YMR270C 48 + CCTATCGAAGATATTATACG P|17|R P|17|L I|18|M silent|ATC>ATT|I|18 RRN9 Regulation of RNA polymerase I 365.0 0 0 0 0 0.08359008322434436 P53437 38.372757289825024 35.0 0.0 no 10852 chrXIII_820360 28535 essential YMR277W 104 + TGTCTATAAGTTCTGGTATT silent|GTC>GTG|V|36 silent|GTC>GTT|V|36 FCP1 tfiiF-associating component of Ctd Phosphatase 732.0 0 0 0 0 0.590473039244249 Q03254 41.95660690509681 30.0 1.0 no 10853 chrXIII_820392r 28536 essential YMR277W 139 - ATCATCGTCACCAGTGTCTG D|53|H D|53|N D|52|H D|52|N FCP1 tfiiF-associating component of Ctd Phosphatase 732.0 0 0 0 0 0.5317582039160373 Q03254 0.12564687430858612 0.5093259811401367 0.09751690924167633 0.3700491189956665 52.48626623391573 50.0 1.0 no 10854 chrXIII_820415 28537 essential YMR277W 159 + AACGAGCACGATGTTTCCCC N|54|K silent|AAC>AAT|N|54 H|56|D H|56|Y FCP1 tfiiF-associating component of Ctd Phosphatase 732.0 0 0 0 0 0.12624764220577153 Q03254 0.8394650816917419 0.6593932509422302 0.5402244925498962 53.170579644573316 55.00000000000001 1.0 no 10855 chrXIII_820466r 28542 essential YMR277W 213 - TCACGCAGTTGTTTGGTTGG R|77|P R|77|H E|78|Q E|78|K FCP1 tfiiF-associating component of Ctd Phosphatase 732.0 0 1 0 0 -1.4444607435346897 Q03254 0.1819140613079071 0.1592346578836441 0.035412561148405075 0.027798527851700783 51.94975912649841 50.0 1.0 no 10856 chrXIII_820499 28545 essential YMR277W 243 + TTCTTCGAAAGTCCCTACGA F|82|L silent|TTC>TTT|F|82 F|83|L silent|TTC>TTT|F|83 FCP1 tfiiF-associating component of Ctd Phosphatase 732.0 0 0 0 0 0.9074161864794568 Q03254 0.06043361499905586 0.028238860890269283 48.086028890259975 45.0 1.0 no 10857 chrXIII_820498 28546 essential YMR277W 242 + ATTCTTCGAAAGTCCCTACG F|82|L silent|TTC>TTT|F|82 F|83|L silent|TTC>TTT|F|83 FCP1 tfiiF-associating component of Ctd Phosphatase 732.0 0 0 0 0 0.17142696662238388 Q03254 0.06043361499905586 0.028238860890269283 46.949700508586204 45.0 1.0 no 10858 chrXIII_820512r 28548 essential YMR277W 259 - ACTAATCAAGTCCCCCTCGT S|93|T S|93|N L|91|F silent|TTG>TTA|L|91 FCP1 tfiiF-associating component of Ctd Phosphatase 732.0 0 0 0 0 0.40174072848137865 Q03254 0.3528402149677277 0.4185323715209961 0.02623516134917736 55.09426546663559 50.0 1.0 no 10859 chrXIII_820813r 28558 essential YMR277W 560 - TCGTAGGGTCCACGCCACAA silent|ACG>ACC|T|193 silent|ACG>ACA|T|193 FCP1 tfiiF-associating component of Ctd Phosphatase 732.0 0 0 0 0 -0.9784090562676944 Q03254 56.85823187577341 60.0 1.0 no 10860 chrXIII_820829r 28559 essential YMR277W 576 - TTCTTCCACTCTGCAATCGT K|198|N silent|AAG>AAA|K|198 W|197|C W|197|* FCP1 tfiiF-associating component of Ctd Phosphatase 732.0 0 0 0 0 1.2037883545622088 Q03254 0.2425417453050613 0.0 52.02110965676405 45.0 1.0 no 10861 chrXIII_820855r 28560 essential YMR277W 602 - TTTCAAAATTCGGATTATTG E|207|Q E|207|K FCP1 tfiiF-associating component of Ctd Phosphatase 732.0 0 0 0 0 0.10201923824721074 Q03254 0.2525733411312103 0.3167286515235901 34.3296380102704 25.0 1.0 no 10862 chrXIII_820925r 28561 essential YMR277W 672 - TCGTCATTCATGTACATAAG D|231|H D|231|N D|230|H D|230|N FCP1 tfiiF-associating component of Ctd Phosphatase 732.0 0 0 0 0 -0.07195965647481886 Q03254 0.05154325067996979 0.1280166357755661 0.07385111600160599 0.23598068952560425 40.46715754392983 35.0 1.0 no 10863 chrXIII_821007r 28566 essential YMR277W 754 - AGCGAAAAATTCCTTTAAAC A|258|P A|258|T FCP1 tfiiF-associating component of Ctd Phosphatase 732.0 0 0 0 0 0.2886767937001137 Q03254 0.08209054917097093 0.1500827521085739 35.07487138497196 30.0 1.0 no 10864 chrXIII_821056 28567 essential YMR277W 800 + TATCTACACAATGGCTACAA I|268|M silent|ATC>ATT|I|268 Y|269|* silent|TAC>TAT|Y|269 FCP1 tfiiF-associating component of Ctd Phosphatase 732.0 0 0 0 0 -0.10573793126295096 Q03254 0.006591794546693564 40.61355962011425 35.0 1.0 no 10865 chrXIII_821111r 28570 essential YMR277W 858 - TCGCCAAACAATTCGCCCGT G|292|A G|292|D D|293|H D|293|N FCP1 tfiiF-associating component of Ctd Phosphatase 732.0 0 0 0 0 0.20810688772426428 Q03254 0.1445746123790741 0.008334607817232609 0.0051224417984485635 0.01589132659137249 53.347729231127225 55.00000000000001 1.0 no 10866 chrXIII_821191 28572 essential YMR277W 935 + TTTCCCCACTGACCAGTCAA F|313|L silent|TTC>TTT|F|313 P|314|A P|314|S FCP1 tfiiF-associating component of Ctd Phosphatase 732.0 0 0 0 0 -0.31484513973733363 Q03254 0.0 0.0 0.0 55.57794780534602 50.0 1.0 no 10867 chrXIII_821194r 28573 essential YMR277W 941 - CAACCATTGACTGGTCAGTG V|320|L V|320|I M|319|I M|319|I FCP1 tfiiF-associating component of Ctd Phosphatase 732.0 0 0 0 0 -0.4347729195568393 Q03254 0.0 0.0 0.0 0.0 48.1353510118916 50.0 1.0 no 10868 chrXIII_821196r 28575 essential YMR277W 943 - TACAACCATTGACTGGTCAG V|321|L V|321|I V|320|L V|320|I FCP1 tfiiF-associating component of Ctd Phosphatase 732.0 0 0 0 0 -1.5533756382844468 Q03254 0.07145780324935913 0.10120272636413574 0.0 0.0 45.50499032141993 45.0 1.0 no 10869 chrXIII_821318 28577 essential YMR277W 1062 + TTCTTGCCCAAACAATCTAC F|355|L silent|TTC>TTT|F|355 P|357|A P|357|S FCP1 tfiiF-associating component of Ctd Phosphatase 732.0 0 0 0 0 0.16691329527188387 Q03254 0.0 0.0 0.0 45.054233744993546 40.0 1.0 no 10870 chrXIII_821325r 28579 essential YMR277W 1072 - TAGCATTCCTGTAGATTGTT M|363|I M|363|I FCP1 tfiiF-associating component of Ctd Phosphatase 732.0 0 0 0 0 0.5678534105964659 Q03254 0.3177620768547058 0.3177620768547058 47.04077960165949 35.0 1.0 no 10871 chrXIII_821333 28580 essential YMR277W 1077 + TCTACAGGAATGCTACAACT S|360|C S|360|F T|361|R T|361|I FCP1 tfiiF-associating component of Ctd Phosphatase 732.0 0 0 0 0 0.5848086810685476 Q03254 0.06647021323442459 0.16232146322727206 0.5057193040847778 0.18238167464733124 42.82942065771885 40.0 1.0 no 10872 chrXIII_821334 28581 essential YMR277W 1078 + CTACAGGAATGCTACAACTA T|361|R T|361|I FCP1 tfiiF-associating component of Ctd Phosphatase 732.0 0 0 0 0 0.09382098156297196 Q03254 0.5057193040847778 0.18238167464733124 41.38166588010285 40.0 1.0 no 10873 chrXIII_821476r 28583 essential YMR277W 1223 - CCTCAGCAGTCGCCAGTTGA E|414|Q E|414|K E|414|D silent|GAG>GAA|E|414 FCP1 tfiiF-associating component of Ctd Phosphatase 732.0 0 0 0 0 -1.7247596934914529 Q03254 0.5272028446197511 0.8204709887504578 0.6532942056655884 60.24734934552402 60.0 1.0 no 10874 chrXIII_821501r 28585 essential YMR277W 1248 - TCTTTGGATTCGTTCGCAGG E|423|Q E|423|K FCP1 tfiiF-associating component of Ctd Phosphatase 732.0 0 0 0 0 0.5654805902550479 Q03254 0.22242631018161774 0.2371822744607925 51.11228523335058 50.0 1.0 no 10875 chrXIII_821504r 28586 essential YMR277W 1251 - TCTTCTTTGGATTCGTTCGC E|424|Q E|424|K E|423|Q E|423|K FCP1 tfiiF-associating component of Ctd Phosphatase 732.0 0 0 0 0 0.16014332493860686 Q03254 0.5619838833808899 0.8718990683555603 0.22242631018161774 0.2371822744607925 50.54399327244739 45.0 1.0 no 10876 chrXIII_821517r 28587 essential YMR277W 1264 - TTTCTTGGTCAACTCTTCTT K|427|N silent|AAG>AAA|K|427 FCP1 tfiiF-associating component of Ctd Phosphatase 732.0 0 0 0 0 -0.8391402095109308 Q03254 0.049551378935575485 47.104031185136826 35.0 1.0 no 10877 chrXIII_821532r 28588 essential YMR277W 1279 - TGCTGAATATTCTAGTTTCT A|433|P A|433|T FCP1 tfiiF-associating component of Ctd Phosphatase 732.0 0 0 0 0 -0.06917192829245143 Q03254 0.3075646460056305 0.6599323749542236 42.08701244170345 30.0 1.0 no 10878 chrXIII_821787 28591 essential YMR277W 1531 + TTTCAGGATTAATACCCCTC S|512|* S|512|L FCP1 tfiiF-associating component of Ctd Phosphatase 732.0 0 0 0 0 -1.2394559455442 Q03254 0.0 48.048731252576026 40.0 1.0 no 10879 chrXIII_821870r 28594 essential YMR277W 1617 - GTCGTCAGGTAATCTATATC silent|ACG>ACC|T|545 silent|ACG>ACA|T|545 silent|CTG>CTC|L|544 silent|CTG>CTA|L|544 FCP1 tfiiF-associating component of Ctd Phosphatase 732.0 0 0 0 0 0.8643070969333677 Q03254 44.34420663090788 40.0 1.0 no 10880 chrXIII_832451r 28595 essential YMR281W 115 - CTGCAATGATGCATTGTTTC L|44|F silent|TTG>TTA|L|44 GPI12 GlycosylPhosphatidylInositol anchor biosynthesis 304.0 0 0 0 0 0.37385473284702003 P23797 0.9587849974632264 0.5847289562225342 44.92029406485858 40.0 1.0 no 10881 chrXIII_832452r 28596 essential YMR281W 116 - GCTGCAATGATGCATTGTTT Q|45|H silent|CAG>CAA|Q|45 L|44|F silent|TTG>TTA|L|44 GPI12 GlycosylPhosphatidylInositol anchor biosynthesis 304.0 0 0 0 0 -0.3731896074278577 P23797 0.9570760130882264 0.9587849974632264 0.2348014861345291 0.5847289562225342 47.59803012379615 40.0 1.0 no 10882 chrXIII_832602 28600 essential YMR281W 263 + TAACATAATCTGCTTATCAA N|89|K silent|AAC>AAT|N|89 GPI12 GlycosylPhosphatidylInositol anchor biosynthesis 304.0 0 0 0 0 0.14021773323113562 P23797 0.9439849853515624 0.0 35.92099760496797 25.0 1.0 no 10883 chrXIII_832603 28601 essential YMR281W 264 + AACATAATCTGCTTATCAAA N|89|K silent|AAC>AAT|N|89 GPI12 GlycosylPhosphatidylInositol anchor biosynthesis 304.0 0 0 0 0 0.8581300405690471 P23797 0.9439849853515624 0.0 35.220639987491275 25.0 1.0 no 10884 chrXIII_832701 28605 essential YMR281W 362 + AGCAGTCTCCGTACAGGTGA A|122|G A|122|V silent|GTC>GTG|V|123 silent|GTC>GTT|V|123 GPI12 GlycosylPhosphatidylInositol anchor biosynthesis 304.0 0 0 0 0 1.0797010250261652 P23797 0.9484469890594482 0.9504740238189696 0.38135772943496704 0.2870199680328369 56.33986688148872 55.00000000000001 1.0 no 10885 chrXIII_832676r 28606 essential YMR281W 340 - TTCATTGTGTAGCAATAAAG E|120|Q E|120|K GPI12 GlycosylPhosphatidylInositol anchor biosynthesis 304.0 0 0 0 0 0.3993895279847905 P23797 0.956179976463318 0.9475290179252625 0.6722751259803772 0.5564913153648376 36.53846200010963 30.0 1.0 no 10886 chrXIII_832822 28608 essential YMR281W 483 + ATCGTTACCTTTGATTCATA I|162|M silent|ATC>ATT|I|162 GPI12 GlycosylPhosphatidylInositol anchor biosynthesis 304.0 0 0 0 0 0.4991605443791268 P23797 0.9598389863967896 0.06603935360908507 43.49733473569575 30.0 1.0 no 10887 chrXIII_832883r 28609 essential YMR281W 547 - ATCATCCACCAACTTTTTAA D|189|H D|189|N D|188|H D|188|N GPI12 GlycosylPhosphatidylInositol anchor biosynthesis 304.0 0 0 0 0 1.2162955350661226 P23797 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.13430002331733704 0.39625033736228943 0.0873403549194336 0.4884994924068451 43.04982146639446 30.0 1.0 no 10888 chrXIII_845638 28611 essential YMR288W 67 + ATTCTATTCCTCAGGATTTG S|24|C S|24|F 0 0 0 0 0.10657243287333276 P49955 0.945252001285553 0.9294660091400146 45.14162811535346 35.0 1.0 no 10889 chrXIII_845639 28612 essential YMR288W 68 + TTCTATTCCTCAGGATTTGA S|24|C S|24|F 0 0 0 0 0.6905587065486338 P49955 0.945252001285553 0.9294660091400146 46.4238463747834 35.0 1.0 no 10890 chrXIII_845666r 28613 essential YMR288W 98 - TACGTGCAGCTTCTTTCTGC R|39|P R|39|H A|38|P A|38|T 0 0 0 0 0.019402487867698992 P49955 0.9099509716033936 0.9570810198783876 0.9573720097541808 0.9523990154266356 53.93015352927075 50.0 1.0 no 10891 chrXIII_845833 28616 essential YMR288W 262 + CCCAAGACGCTGTCGTGCCA Q|89|E Q|89|* silent|ACC>ACG|T|88 silent|ACC>ACT|T|88 0 0 0 0 -0.13479803425129533 P49955 0.9590039849281312 0.9239841103553772 59.76110279375786 65.0 1.0 no 10892 chrXIII_845800r 28617 essential YMR288W 232 - AGACGTAACAGTTTGTGTAT silent|ACG>ACC|T|83 silent|ACG>ACA|T|83 0 0 0 0 0.09702158881843714 P49955 41.89055451779456 35.0 1.0 no 10893 chrXIII_845833r 28618 essential YMR288W 265 - CCTTGGCACGACAGCGTCTT R|95|T R|95|K silent|GTG>GTC|V|93 silent|GTG>GTA|V|93 0 0 0 0 0.11875135698673756 P49955 0.932735025882721 0.955805003643036 0.450575202703476 0.9276139736175536 57.16041642159757 60.0 1.0 no 10894 chrXIII_845894 28622 essential YMR288W 323 + ACCTGATGAATCTTCAACAG P|109|R P|109|L P|109|A P|109|S 0 0 0 0 0.14183542329637544 P49955 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.04967140406370163 0.2831380665302277 0.4245983958244324 0.07834087312221527 41.96768073692351 40.0 1.0 no 10895 chrXIII_845895r 28623 essential YMR288W 327 - ACCGCTGTTGAAGATTCATC silent|GCG>GCC|A|115 silent|GCG>GCA|A|115 V|116|L V|116|I 0 0 0 0 0.8083053445568165 P49955 0.9539830088615416 0.9574310183525084 0.32884347438812256 0.19617339968681333 47.44446074333979 45.0 1.0 no 10896 chrXIII_846064r 28625 essential YMR288W 496 - TTTCAGAAGTAACATCGACA silent|CTG>CTC|L|171 silent|CTG>CTA|L|171 0 0 0 0 -0.2285044186671382 P49955 39.40677809563221 35.0 1.0 no 10897 chrXIII_846135 28626 essential YMR288W 564 + ACCGATAAAGCTGTTACATT silent|ACC>ACG|T|189 silent|ACC>ACT|T|189 T|189|S T|189|I 0 0 0 0 0.4952595694462684 P49955 0.9491789937019348 0.9472420215606691 0.266086608171463 0.01725425012409687 42.288470624043605 35.0 1.0 no 10898 chrXIII_846136r 28627 essential YMR288W 568 - ACCAAATGTAACAGCTTTAT G|196|R G|196|S G|196|A G|196|D 0 0 0 0 -0.4265777178953594 P49955 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.004944517277181149 0.00923802237957716 0.01326085813343525 0.007428103126585483 39.764884550277145 30.0 1.0 no 10899 chrXIII_846186r 28628 essential YMR288W 618 - AAACTTCTGTCTAGTAATAT S|212|T S|212|N R|211|T R|211|K 0 0 0 0 -1.0583700476487627 P49955 0.9512869715690612 0.9536849856376648 0.932735025882721 0.955805003643036 1.0 0.2882210910320282 0.5089330673217773 1.0 36.06554520742026 25.0 1.0 no 10900 chrXIII_846246 28630 essential YMR288W 675 + GATCGCGTCCTTTACCAGCT R|227|G R|227|C silent|CGC>CGG|R|227 silent|CGC>CGT|R|227 0 1 0 0 -0.7654386620092807 P49955 0.8994590044021606 0.8926740288734436 0.055486101657152176 0.0006165147060528398 57.43978454398211 55.00000000000001 1.0 no 10901 chrXIII_846313r 28632 essential YMR288W 745 - ATCTTCATCTATTAGCAATG D|255|H D|255|N E|254|Q E|254|K 0 0 0 0 0.4016548214642167 P49955 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.003031929256394505 0.1123005822300911 0.15714126825332642 0.18014496564865112 39.85680947537816 30.0 1.0 no 10902 chrXIII_846314r 28633 essential YMR288W 746 - GATCTTCATCTATTAGCAAT D|255|H D|255|N E|254|Q E|254|K 0 0 0 0 -0.05985677576204704 P49955 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.003031929256394505 0.1123005822300911 0.15714126825332642 0.18014496564865112 41.09165353936152 30.0 1.0 no 10903 chrXIII_846369 28637 essential YMR288W 798 + ACCAATCTGTCTACAGTCGC silent|ACC>ACG|T|267 silent|ACC>ACT|T|267 T|267|S T|267|I 0 0 0 0 0.6787170943687322 P49955 0.9491789937019348 0.9472420215606691 1.0 0.0044781086035072795 51.220082929753005 50.0 1.0 no 10904 chrXIII_846490r 28641 essential YMR288W 922 - AAGCAATTGATTAACACCAA L|313|F silent|TTG>TTA|L|313 0 0 0 0 0.5881550630910031 P49955 0.9587849974632264 0.11953058838844301 37.50823846032517 30.0 1.0 no 10905 chrXIII_846656 28646 essential YMR288W 1085 + CCTAATGGATGATCACGTTC L|363|V silent|CTA>TTA|L|363 0 0 0 0 0.4427594123424037 P49955 0.9512209892272948 0.047583214938640594 45.32214313917473 45.0 1.0 no 10906 chrXIII_846751 28648 essential YMR288W 1180 + ACGTTGTACTGGAGCCATTA N|394|K silent|AAC>AAT|N|394 0 0 0 0 -1.4798240702771133 P49955 0.9439849853515624 0.2400318384170532 50.09325328902661 45.0 1.0 no 10907 chrXIII_846765r 28650 essential YMR288W 1197 - CTTCTTATACCCTTCCATAA R|405|T R|405|K 0 0 0 0 -1.3519023174754283 P49955 0.932735025882721 0.955805003643036 0.023813646286726 0.4964123070240021 47.450542163237174 35.0 1.0 no 10908 chrXIII_846862r 28652 essential YMR288W 1294 - TGCTTCTGTGGTATAATAAC A|438|P A|438|T E|437|Q E|437|K 0 0 0 0 0.7915431402410393 P49955 0.9573720097541808 0.9523990154266356 0.956179976463318 0.9475290179252625 0.011709273792803288 0.14869001507759094 0.1853511780500412 0.011515052989125252 40.851875448016585 35.0 1.0 no 10909 chrXIII_846976r 28653 essential YMR288W 1408 - TCTCAGAAATTTTGGCGTTA silent|CTG>CTC|L|475 silent|CTG>CTA|L|475 R|476|T R|476|K 0 0 0 0 0.16040196905530962 P49955 0.932735025882721 0.955805003643036 0.4824406206607818 0.9905171394348145 42.861099936659116 35.0 1.0 no 10910 chrXIII_847184r 28655 essential YMR288W 1616 - TTACTGTTCTAGTAACAGCA V|545|L V|545|I 0 0 0 0 0.4411637288413584 P49955 0.9539830088615416 0.9574310183525084 0.35789069533348083 0.5483185052871704 43.46133238530615 35.0 1.0 no 10911 chrXIII_847299 28656 essential YMR288W 1728 + TCTATAATCTTTAAAGGGTT S|577|C S|577|F 0 0 0 0 0.5631864024501226 P49955 0.945252001285553 0.9294660091400146 0.05429064109921456 0.05486338958144188 36.71465103713132 25.0 1.0 no 10912 chrXIII_847519r 28662 essential YMR288W 1951 - CTCTGGATATACTTCGCCTA E|657|Q E|657|K 0 0 0 0 -0.6879424604409503 P49955 0.956179976463318 0.9475290179252625 0.019011028110980988 0.01471090316772461 49.81262306012303 45.0 1.0 no 10913 chrXIII_847720r 28665 essential YMR288W 2152 - CCATTCTTTAGGAGGTGCAT W|724|S W|724|* E|723|Q E|723|K 0 0 0 0 -1.4412805822853059 P49955 0.8858469724655151 0.956179976463318 0.9475290179252625 0.004225329030305147 0.0049565895460546025 0.004503381438553332 51.293162427111334 45.0 1.0 no 10914 chrXIII_850475 28666 essential YMR290C 1097 - AATCTCTTGGATCATCAGGA D|372|H D|372|N R|371|T R|371|K HAS1 Helicase Associated with Set1 505.0 0 0 0 0 -1.4322762503919817 Q03532 0.9486550092697144 0.956179976463318 0.932735025882721 0.955805003643036 0.0033674202859401703 0.0073368139564991 0.09318258613348007 1.0 45.458285184206545 40.0 0.0 no 10915 chrXIII_850630r 28668 essential YMR290C 939 + TTGCCAGTCCTCGAATTACA P|315|A P|315|S P|315|R P|315|L HAS1 Helicase Associated with Set1 505.0 0 0 0 0 0.663464285176861 Q03532 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.14011512696743011 0.17774099111557007 0.08374397456645966 0.055488377809524536 50.67837109151975 45.0 0.0 no 10916 chrXIII_850791 28670 essential YMR290C 781 - GCCTTGTTCTAATCCATCTG G|267|R G|267|S G|267|A G|267|D HAS1 Helicase Associated with Set1 505.0 0 0 0 0 -1.6119876844341052 Q03532 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 51.394236474449826 45.0 0.0 no 10917 chrXIII_850803 28673 essential YMR290C 769 - TCCATCTGCGGTGGAGTTGT G|263|R G|263|R G|263|A G|263|E HAS1 Helicase Associated with Set1 505.0 0 0 0 0 -0.4864574775879222 Q03532 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.053590305149555206 0.053590305149555206 0.007567837368696928 0.009858772158622742 57.50526133941969 55.00000000000001 0.0 no 10918 chrXIII_850883r 28678 essential YMR290C 686 + TACACAAACGACCAAAGTTG T|230|R T|230|I Q|231|E Q|231|* HAS1 Helicase Associated with Set1 505.0 0 0 0 0 0.4629672005123376 Q03532 0.9476869702339172 0.9472420215606691 0.9590039849281312 0.0 0.0 0.011445949785411358 38.35102244714233 40.0 0.0 no 10919 chrXIII_850872 28679 essential YMR290C 700 - TCTAGCCAAATCCTCAACTT R|240|T R|240|K A|239|P A|239|T HAS1 Helicase Associated with Set1 505.0 0 0 0 0 -0.8404439753433868 Q03532 0.932735025882721 0.955805003643036 0.9573720097541808 0.9523990154266356 0.06727015227079391 0.5590965747833252 0.07319511473178864 0.0658096894621849 8.567600250244139 2.2685000896453857 47.141960262418536 40.0 0.0 no 10920 chrXIII_851041r 28682 essential YMR290C 528 + GATCACTTACAAAATACAAA H|178|D H|178|Y H|178|Q silent|CAC>CAT|H|178 HAS1 Helicase Associated with Set1 505.0 0 0 0 0 0.34370085356843005 Q03532 0.9473130106925964 0.9489949941635132 0.9588389992713928 0.0 0.0 0.0 31.592667717046933 25.0 0.0 no 10921 chrXIII_851074r 28683 essential YMR290C 495 + AACATGTTGATTGCTACCCC N|166|K silent|AAC>AAT|N|166 HAS1 Helicase Associated with Set1 505.0 0 0 0 0 0.4266118258134621 Q03532 0.9439849853515624 0.006503022741526364 50.31043962761345 45.0 0.0 no 10922 chrXIII_851347 28686 essential YMR290C 225 - ACATCCCTACCGGCCAAAAG V|82|L V|82|I D|81|H D|81|N HAS1 Helicase Associated with Set1 505.0 0 0 0 0 -3.470427114999868 Q03532 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 0.4128650426864624 0.3715086579322815 0.001890154206193984 0.060513798147439964 -0.7274199724197388 -1.2045400142669678 51.974758605805114 55.00000000000001 0.0 yes 10923 chrXIII_851356r 28688 essential YMR290C 213 + ACTATCCCACCTCTTTTGGC T|72|S T|72|I I|73|M silent|ATC>ATT|I|73 HAS1 Helicase Associated with Set1 505.0 0 0 0 0 0.14951717864114 Q03532 0.9491789937019348 0.9472420215606691 0.9598389863967896 1.0 0.029247887432575226 0.0030614526476711035 56.74794167318555 50.0 0.0 no 10924 chrXIII_851518 28689 essential YMR290C 54 - GTGCTCTTTTCATCTACTAC S|24|T S|24|N K|23|N silent|AAG>AAA|K|23 HAS1 Helicase Associated with Set1 505.0 0 0 0 0 1.4606620518761608 Q03532 0.9512869715690612 0.9536849856376648 0.9355990290641784 0.5687376856803894 0.5027426481246948 0.4856676459312439 47.823620126328926 40.0 0.0 no 10925 chrXIII_855808 28693 high_effect YMR293C 966 - GTTCCGAATTTGGACCTAGT G|328|A G|328|E G|328|R G|328|R HER2 Hmg2p ER Remodeling 464.0 0 0 0 0 0.22100599598465748 Q03557 0.9499930143356324 0.9438679814338684 0.941340982913971 0.941340982913971 0.0 0.0 0.0 0.0 1.583899974822998 2.0126399993896484 3.2271199226379395 3.2271199226379395 49.906236701003074 45.0 0.0 no 10926 chrXIII_855888 28696 high_effect YMR293C 886 - ACCATCATACCTTGATAAAT G|302|R G|302|S G|302|A G|302|D HER2 Hmg2p ER Remodeling 464.0 0 0 0 0 0.05658208046144975 Q03557 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 17.474540710449222 10.407159805297852 7.46265983581543 18.680320739746094 40.81992670754136 30.0 0.0 no 10927 chrXIII_856041r 28700 high_effect YMR293C 730 + GCCATGAAAGTATGCCCATT H|245|D H|245|Y S|244|R silent|AGC>AGT|S|244 HER2 Hmg2p ER Remodeling 464.0 0 0 0 0 -1.3515553721635678 Q03557 0.9473130106925964 0.9489949941635132 0.9417110085487366 0.20987191796302795 1.0 0.5425716638565063 0.3337999880313873 0.07159999758005142 0.029279999434947968 -0.7889999747276306 -0.7799999713897705 50.68998680042893 45.0 0.0 no 10928 chrXIII_856125 28701 high_effect YMR293C 649 - TTCACGCAATTCCACACTTA E|223|Q E|223|K R|222|P R|222|H HER2 Hmg2p ER Remodeling 464.0 0 0 0 0 -0.13916733861781805 Q03557 0.956179976463318 0.9475290179252625 0.9099509716033936 0.9570810198783876 0.5381542444229126 0.8671821355819702 0.020878031849861145 0.01868443377315998 0.05217999964952469 0.0494999997317791 5.776700019836426 2.931260108947754 46.91447390214421 40.0 0.0 no 10929 chrXIII_856225r 28702 high_effect YMR293C 546 + TCTCAATCTTTAGACACTGT Q|184|E Q|184|* S|183|C S|183|F HER2 Hmg2p ER Remodeling 464.0 0 0 0 0 -0.8796535655488527 Q03557 0.9590039849281312 0.945252001285553 0.9294660091400146 0.10862711817026137 0.005689668934792279 0.0022836176212877035 0.9014000296592712 -0.7828599810600281 8.395700454711914 43.315798928783686 35.0 0.0 no 10930 chrXIII_856301 28704 high_effect YMR293C 473 - AAACAGATCCATAGCATGCG V|164|L V|164|I HER2 Hmg2p ER Remodeling 464.0 0 0 0 0 -1.1625963944590565 Q03557 0.9539830088615416 0.9574310183525084 0.12166571617126465 0.4173527657985687 0.10627999901771544 -0.1174200028181076 44.68239529300706 45.0 0.0 no 10931 chrXIII_856335 28705 high_effect YMR293C 439 - GCCACCAGTATCTGTTCCCA G|153|R G|153|S G|153|A G|153|D HER2 Hmg2p ER Remodeling 464.0 0 1 0 0 -1.8040914573747275 Q03557 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 17.531639099121097 10.531880378723145 6.822080135345459 13.672900199890135 61.44084125345882 55.00000000000001 0.0 no 10932 chrXIII_856548 28711 high_effect YMR293C 226 - TTTCACTACTGTTGCATCGA silent|GTG>GTC|V|81 silent|GTG>GTA|V|81 V|81|L V|81|M HER2 Hmg2p ER Remodeling 464.0 0 0 0 0 0.5152841315643638 Q03557 0.9539830088615416 0.9587630033493042 0.2774791717529297 0.11906088143587112 -0.5869600176811218 1.2410199642181396 47.23146766757974 40.0 0.0 no 10933 chrXIII_856549 28712 high_effect YMR293C 225 - TTCACTACTGTTGCATCGAA silent|GTG>GTC|V|81 silent|GTG>GTA|V|81 V|81|L V|81|M HER2 Hmg2p ER Remodeling 464.0 0 0 0 0 0.7422951212659743 Q03557 0.9539830088615416 0.9587630033493042 0.2774791717529297 0.11906088143587112 -0.5869600176811218 1.2410199642181396 45.3915713932455 40.0 0.0 no 10934 chrXIII_859734 28717 essential YMR296C 1138 - GGCAGAAAAACAATATGCAT A|386|P A|386|T LCB1 Long-Chain Base 558.0 0 0 0 0 -7.486674404770062 P25045 0.0 0.0 -1.6806000471115112 -0.0729999989271164 37.28894770417975 35.0 0.0 yes 10935 chrXIII_859775 28719 essential YMR296C 1097 - AACACATAACACTGTCACCC C|372|S C|372|Y M|371|I M|371|I LCB1 Long-Chain Base 558.0 0 0 0 0 -1.4209949861692674 P25045 0.6002010107040405 0.09831050038337708 0.2757601737976074 0.2757601737976074 46.02760858583662 45.0 0.0 no 10936 chrXIII_859836r 28730 essential YMR296C 1033 + CTGCCATTGACATTACCGTT A|346|G A|346|V silent|GCC>GCG|A|346 silent|GCC>GCT|A|346 LCB1 Long-Chain Base 558.0 0 0 0 0 0.4662858029302305 P25045 0.06139415130019187 0.04432675614953041 50.738349959874775 45.0 0.0 no 10937 chrXIII_859837r 28731 essential YMR296C 1032 + ACTGCCATTGACATTACCGT T|345|S T|345|I A|346|G A|346|V LCB1 Long-Chain Base 558.0 0 0 0 0 -0.799414466987858 P25045 1.0 0.0533897690474987 0.06139415130019187 0.04432675614953041 50.91952776992366 45.0 0.0 no 10938 chrXIII_859960 28734 essential YMR296C 912 - TTCTTCAGCTTAGTCAACTC K|310|N silent|AAG>AAA|K|310 silent|CTG>CTC|L|309 silent|CTG>CTA|L|309 LCB1 Long-Chain Base 558.0 0 0 0 0 -0.15032609940909475 P25045 0.0 46.934074980261926 40.0 0.0 no 10939 chrXIII_859966 28735 essential YMR296C 906 - AGCTTAGTCAACTCAGGCAA K|308|N silent|AAG>AAA|K|308 LCB1 Long-Chain Base 558.0 0 0 0 0 -0.011941831476851673 P25045 0.027388283982872963 48.443652603026926 45.0 0.0 no 10940 chrXIII_859988 28736 essential YMR296C 884 - GAGCTAAATCGCCCGAGTTG A|301|P A|301|T LCB1 Long-Chain Base 558.0 0 0 0 0 0.3921119552357374 P25045 0.2908362150192261 0.3830443322658539 50.64137696362354 55.00000000000001 0.0 no 10941 chrXIII_860055 28737 essential YMR296C 817 - TTTCTCAAGTTTCTCCTGTT E|278|D silent|GAG>GAA|E|278 E|278|Q E|278|K LCB1 Long-Chain Base 558.0 0 0 0 0 -0.6458722181422994 P25045 0.608712375164032 0.5268924832344055 0.9771785140037536 49.07137279235764 35.0 0.0 no 10942 chrXIII_860306 28743 essential YMR296C 566 - CCAACGTGTAATGAACGTCC L|195|F silent|TTG>TTA|L|195 silent|ACG>ACC|T|194 silent|ACG>ACA|T|194 LCB1 Long-Chain Base 558.0 0 0 0 0 0.9097738833907508 P25045 0.049433525651693344 46.02978784203066 50.0 0.0 no 10943 chrXIII_860359r 28745 essential YMR296C 510 + ACTATCAAGAATTACGGTGT T|171|S T|171|I I|172|M silent|ATC>ATT|I|172 LCB1 Long-Chain Base 558.0 0 0 0 0 -0.20024107883481115 P25045 0.09645605087280272 0.6779007315635681 0.03131285309791565 -1.0814000368118286 40.388664786141995 35.0 0.0 no 10944 chrXIII_860360r 28746 essential YMR296C 509 + CACTATCAAGAATTACGGTG T|171|S T|171|I I|172|M silent|ATC>ATT|I|172 LCB1 Long-Chain Base 558.0 0 0 0 0 -0.9472005528341778 P25045 0.09645605087280272 0.6779007315635681 0.03131285309791565 -1.0814000368118286 39.37051586026456 40.0 0.0 no 10945 chrXIII_860361 28747 essential YMR296C 511 - CACACCGTAATTCTTGATAG V|177|L V|177|M G|176|A G|176|D LCB1 Long-Chain Base 558.0 0 0 0 0 -0.5495868461635439 P25045 0.18112295866012573 0.014689647592604159 0.0 0.0 -1.5135999917984009 0.15479999780654907 1.388200044631958 3.4848999977111816 42.39945060405007 40.0 0.0 no 10946 chrXIII_860463 28750 essential YMR296C 409 - CTTCTCCTGCAGGTTGTTTC E|142|D silent|GAG>GAA|E|142 E|142|Q E|142|K LCB1 Long-Chain Base 558.0 0 0 0 0 -0.2067798431365808 P25045 0.6297969818115234 0.6087611317634583 0.924351930618286 56.16566293439513 50.0 0.0 no 10947 chrXIII_860468r 28751 essential YMR296C 401 + TATCACCAGAAACAACCTGC I|135|M silent|ATC>ATT|I|135 T|136|S T|136|I LCB1 Long-Chain Base 558.0 0 0 0 0 0.10505938085348564 P25045 0.06393563002347946 0.9483676552772522 0.18682725727558136 44.7747452922589 45.0 0.0 no 10948 chrXIII_860499 28752 essential YMR296C 373 - GTTCTGAATGGGCATTTCCA Q|130|H silent|CAG>CAA|Q|130 LCB1 Long-Chain Base 558.0 0 0 0 0 0.11009080532582023 P25045 0.17820779979228973 50.99867739253824 45.0 0.0 no 10949 chrXIII_860609 28758 essential YMR296C 263 - CGTCAATCTCCTGGGGCGAT D|94|H D|94|N LCB1 Long-Chain Base 558.0 0 0 0 0 -0.6930995882971231 P25045 0.0115217762067914 0.04446452483534813 55.88300557015521 60.0 0.0 no 10950 chrXIII_860652 28760 essential YMR296C 220 - ACTCTTTTTCTGTTGTGGCT K|79|N silent|AAG>AAA|K|79 S|80|T S|80|N LCB1 Long-Chain Base 558.0 0 0 0 0 -1.178602741897333 P25045 0.7475701570510864 0.21227654814720154 0.18764933943748474 52.07130696533028 40.0 0.0 no 10951 chrXIII_860707r 28762 essential YMR296C 162 + TACAGGACCACGGTTGAGAT Y|55|* silent|TAC>TAT|Y|55 LCB1 Long-Chain Base 558.0 0 0 0 0 -2.307757894925752 P25045 48.91016641759575 50.0 0.0 yes 10952 chrXIII_860710 28763 essential YMR296C 162 - ATCTCAACCGTGGTCCTGTA E|60|D silent|GAG>GAA|E|60 E|60|Q E|60|K LCB1 Long-Chain Base 558.0 0 0 0 0 0.7445923422883913 P25045 0.0 0.0 0.0 54.44000656144499 50.0 0.0 no 10953 chrXIII_860717r 28764 essential YMR296C 152 + TGACGATCCATACAGGACCA D|52|E silent|GAC>GAT|D|52 LCB1 Long-Chain Base 558.0 0 0 0 0 0.4549240623826567 P25045 0.030621889978647232 49.582023496449544 50.0 0.0 no 10954 chrXIII_860724r 28765 essential YMR296C 145 + CGCATCATGACGATCCATAC H|50|D H|50|Y H|51|D H|51|Y LCB1 Long-Chain Base 558.0 0 0 0 0 -0.8839927862273049 P25045 0.027413848787546158 0.4979953467845917 0.030981099233031276 0.0363810732960701 47.5814252591801 50.0 0.0 no 10955 chrXIII_860798 28767 essential YMR296C 74 - CCAGATTGAAGTAGTACCAT silent|CTG>CTC|L|31 silent|CTG>CTA|L|31 LCB1 Long-Chain Base 558.0 0 0 0 0 -0.21987805772823413 P25045 45.25116212439451 40.0 0.0 no 10956 chrXIII_860798r 28769 essential YMR296C 71 + CCTATGGTACTACTTCAATC L|25|V silent|CTA>TTA|L|25 LCB1 Long-Chain Base 558.0 0 0 0 0 0.0002231863649486132 P25045 0.1980779618024826 44.6920124242975 40.0 0.0 no 10957 chrXIII_863981 28776 essential YMR298W 162 + CCAATCAAAGAACCCCAGTC P|55|R P|55|L I|56|M silent|ATC>ATT|I|56 LIP1 Lag1p/Lac1p Interacting Protein 150.0 0 0 0 0 0.7083825707829435 Q03579 0.06977703422307968 0.20707719027996066 0.07787670195102693 48.294836700833066 50.0 1.0 no 10958 chrXIII_864001 28778 essential YMR298W 182 + TGGCTCAGTAATCAAGCTTT silent|GGC>GGG|G|62 silent|GGC>GGT|G|62 S|63|* S|63|L LIP1 Lag1p/Lac1p Interacting Protein 150.0 0 0 0 0 -0.007422696007503556 Q03579 0.04561425745487213 46.798047637509505 40.0 1.0 no 10959 chrXIII_864012 28779 essential YMR298W 193 + TCAAGCTTTGGGCACGTGGT I|65|M silent|ATC>ATT|I|65 L|67|V L|67|F LIP1 Lag1p/Lac1p Interacting Protein 150.0 0 0 0 0 0.2563222296968631 Q03579 0.12453038990497588 0.7014458775520325 0.09469591081142427 55.02156468457372 55.00000000000001 1.0 no 10960 chrXIII_864154r 28783 essential YMR298W 338 - TATCTTCGTGAATTGGGTAG D|119|H D|119|N E|118|Q E|118|K LIP1 Lag1p/Lac1p Interacting Protein 150.0 0 0 0 0 0.34873286002330245 Q03579 43.20630259914776 40.0 1.0 no 10961 chrXIII_868086 28784 essential YMR301C 1522 - CACACCAATCACCTTCCTCA V|514|L V|514|M G|513|A G|513|D ATM1 ABC Transporter, Mitochondrial 690.0 0 0 0 0 -0.5033884862804519 P40416 0.010750655084848404 0.00210803747177124 0.27266454696655273 0.0031936238519847393 53.55381742349361 50.0 0.0 no 10962 chrXIII_868229 28790 essential YMR301C 1379 - TTGCGGTTTTCCAGCCTGCT A|466|P A|466|T ATM1 ABC Transporter, Mitochondrial 690.0 0 0 0 0 -0.6565171017639931 P40416 0.0 0.0 61.10052304046246 55.00000000000001 0.0 no 10963 chrXIII_868243r 28792 essential YMR301C 1362 + GCCAGCTTTACCATCCCAGC silent|GCC>GCG|A|455 silent|GCC>GCT|A|455 A|455|G A|455|V ATM1 ABC Transporter, Mitochondrial 690.0 0 0 0 0 0.2111668398532588 P40416 0.0008791987202130258 0.502108633518219 62.644616786710564 60.0 0.0 no 10964 chrXIII_868266 28793 essential YMR301C 1342 - ATTCTTTAAAATTTTCCTAT K|453|N silent|AAG>AAA|K|453 ATM1 ABC Transporter, Mitochondrial 690.0 0 0 0 0 0.9010665993407484 P40416 0.7787963747978209 34.87618456736061 15.0 0.0 no 10965 chrXIII_868267 28794 essential YMR301C 1341 - TTCTTTAAAATTTTCCTATC K|453|N silent|AAG>AAA|K|453 ATM1 ABC Transporter, Mitochondrial 690.0 0 0 0 0 0.2141099739443354 P40416 0.7787963747978209 35.65931474021801 20.0 0.0 no 10966 chrXIII_868308 28795 essential YMR301C 1300 - GTTCTCAAAAGTAATATCGT E|439|D silent|GAG>GAA|E|439 E|439|Q E|439|K ATM1 ABC Transporter, Mitochondrial 690.0 0 0 0 0 -0.03698298301819887 P40416 0.5025372505187988 0.031822025775909424 0.0676291435956955 37.37149376319968 30.0 0.0 no 10967 chrXIII_868309 28796 essential YMR301C 1299 - TTCTCAAAAGTAATATCGTA E|439|D silent|GAG>GAA|E|439 E|439|Q E|439|K ATM1 ABC Transporter, Mitochondrial 690.0 0 0 0 0 -0.27202919698417305 P40416 0.5025372505187988 0.031822025775909424 0.0676291435956955 34.568640822625696 25.0 0.0 no 10968 chrXIII_868297r 28797 essential YMR301C 1308 + ACTTTTGAGAACGTCACGTT T|437|S T|437|I ATM1 ABC Transporter, Mitochondrial 690.0 0 0 0 0 1.3205705170019977 P40416 0.714645266532898 0.14911474287509918 44.19878064135718 40.0 0.0 no 10969 chrXIII_868737 28800 essential YMR301C 871 - CACACTGGCAGCTTTGTTAT V|297|L V|297|M S|296|T S|296|N ATM1 ABC Transporter, Mitochondrial 690.0 0 0 0 0 -0.42991996655871023 P40416 0.2906424403190613 0.09868788719177246 1.0 0.4324398636817932 50.40030596156703 45.0 0.0 no 10970 chrXIII_868791r 28802 essential YMR301C 814 + TCACTATAAAGACGACCGCA T|273|S T|273|I F|272|L silent|TTC>TTT|F|272 ATM1 ABC Transporter, Mitochondrial 690.0 0 0 0 0 -1.9930903435047984 P40416 0.0 0.0 0.01476231496781111 44.31328066291167 45.0 0.0 no 10971 chrXIII_869021 28809 essential YMR301C 587 - AATCTAACTTCATAAGGTGC D|202|H D|202|N ATM1 ABC Transporter, Mitochondrial 690.0 0 0 0 0 0.24150498617375304 P40416 0.002541805151849985 0.010346230119466782 39.801719331239035 35.0 0.0 no 10972 chrXIII_869133r 28810 essential YMR301C 472 + TTCTTTGCTATGGTGTTGCA L|159|V L|159|F ATM1 ABC Transporter, Mitochondrial 690.0 0 0 0 0 0.04194059646766067 P40416 0.32335641980171204 0.05917321145534515 50.83829749908215 40.0 0.0 no 10973 chrXIII_869305 28819 essential YMR301C 303 - CTCACTTTATTGTTGCCTTT silent|GTG>GTC|V|107 silent|GTG>GTA|V|107 V|107|L V|107|M ATM1 ABC Transporter, Mitochondrial 690.0 0 0 0 0 0.336255533057099 P40416 0.6170428991317749 0.13679984211921692 48.61283061009556 35.0 0.0 no 10974 chrXIII_869351 28821 essential YMR301C 257 - TCAAGATTTTCAGTTCCGAG L|92|F silent|TTG>TTA|L|92 ATM1 ABC Transporter, Mitochondrial 690.0 0 1 0 0 0.5688613876731748 P40416 0.021590886637568474 44.52220859043445 40.0 0.0 no 10975 chrXIII_869366r 28823 essential YMR301C 239 + CAGCAAGGCCCCAACCCTCT S|81|R silent|AGC>AGT|S|81 ATM1 ABC Transporter, Mitochondrial 690.0 0 0 0 0 0.6209409941913974 P40416 0.29526230692863464 62.512780128416814 65.0 0.0 no 10976 chrXIII_869485 28826 essential YMR301C 123 - ACAGCTGAATTGAATAACAG V|48|L V|48|M A|47|P A|47|T ATM1 ABC Transporter, Mitochondrial 690.0 0 0 0 0 0.8066881545157728 P40416 0.3308537006378174 0.11562935262918472 0.3254998028278351 0.8368247151374817 36.40194139479547 35.0 0.0 no 10977 chrXIII_869508r 28827 essential YMR301C 97 + TGTCTAAGTTATCAACCCAG S|34|C S|34|F ATM1 ABC Transporter, Mitochondrial 690.0 0 0 0 0 0.6463645086178084 P40416 0.07552745938301086 0.1063569188117981 45.046767193402786 40.0 0.0 no 10978 chrXIII_889798r 28828 essential YMR308C 2401 + ACTTAACTGACACTTACGAA N|801|K silent|AAC>AAT|N|801 T|803|S T|803|I PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 0.8037663866721613 P32337 0.9439849853515624 0.9491789937019348 0.9472420215606691 0.2466818988323212 0.9181259274482728 0.16828854382038114 38.72223979113978 35.0 0.0 no 10979 chrXIII_889801 28830 essential YMR308C 2401 - TTCGTAAGTGTCAGTTAAGT E|807|Q E|807|K PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 -0.12268122244863228 P32337 0.956179976463318 0.9475290179252625 0.21841047704219815 0.3890340924263001 42.780950383227776 35.0 0.0 no 10980 chrXIII_889892r 28832 essential YMR308C 2307 + TATCACAACTCGTTAGTGAA H|771|D H|771|Y H|771|Q silent|CAC>CAT|H|771 PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 -0.7459331027281384 P32337 0.9473130106925964 0.9489949941635132 0.9588389992713928 0.024856291711330414 1.0 0.03468885645270348 40.254019178105644 35.0 0.0 no 10981 chrXIII_890012r 28836 essential YMR308C 2187 + TCTTGTTTACTTGCAGCCAC S|730|C S|730|F PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 0.6331232708664848 P32337 0.945252001285553 0.9294660091400146 0.0528014600276947 0.05128074064850807 51.960822386763255 45.0 0.0 no 10982 chrXIII_890187 28839 essential YMR308C 2015 - TTGCTGATACTTTATCGTCA A|678|P A|678|T PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 0.8028684583287358 P32337 0.9573720097541808 0.9523990154266356 0.0 0.0 44.87319427587943 35.0 0.0 no 10983 chrXIII_890064 28840 essential YMR308C 2138 - CAGCACGAACACCGTCATGT A|719|P A|719|T R|718|P R|718|H PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 0.3345781550477881 P32337 0.9573720097541808 0.9523990154266356 0.9099509716033936 0.9570810198783876 0.3428959250450134 0.6267940998077393 0.0 0.0 51.02407177580465 55.00000000000001 0.0 no 10984 chrXIII_890243 28841 essential YMR308C 1959 - ACTTGAACAACATCCCAATC V|660|L V|660|I PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 0.4444781742099306 P32337 0.9539830088615416 0.9574310183525084 0.99074524641037 0.7610438466072083 43.00785369217015 40.0 0.0 no 10985 chrXIII_890253 28842 essential YMR308C 1949 - CATCCCAATCTGGATATTGT D|656|H D|656|N W|655|C W|655|* PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 0.7423054196508986 P32337 0.9486550092697144 0.956179976463318 0.8858469724655151 0.009302350692451 0.02140813879668713 0.002871082862839103 47.54739030194207 40.0 0.0 no 10986 chrXIII_890305 28844 essential YMR308C 1897 - ACCGACGTCTTGCGTTGCTT G|639|R G|639|S G|639|A G|639|D PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 0.9637433858829714 P32337 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.4595034420490265 1.0 0.7450546622276306 0.5450745224952698 55.96342177839654 55.00000000000001 0.0 no 10987 chrXIII_890398r 28852 essential YMR308C 1801 + ACTTAGAACAAAGTTGGAGC Y|601|* silent|TAC>TAT|Y|601 PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 0.2819538949510714 P32337 39.892332236790025 40.0 0.0 no 10988 chrXIII_890404r 28853 essential YMR308C 1795 + GATCATACTTAGAACAAAGT S|600|* S|600|L PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 -2.0650167989787978 P32337 0.9298099875450134 0.07639415562152863 35.410983319870525 30.0 0.0 yes 10989 chrXIII_890936 28859 essential YMR308C 1266 - CAACATCCATACTGTACTCT C|428|S C|428|Y G|427|A G|427|E PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 0.6251707221027323 P32337 0.9421560168266296 0.9290120005607604 0.9499930143356324 0.9438679814338684 0.2112310379743576 0.020363979041576385 1.0 0.009045151993632315 45.65351848571572 40.0 0.0 no 10990 chrXIII_890942r 28860 essential YMR308C 1257 + CCTCATCCAAGAGTACAGTA H|421|D H|421|Y P|420|R P|420|L PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 0.6198509191201013 P32337 0.9473130106925964 0.9489949941635132 0.9432820081710817 0.9430609941482544 0.02590411528944969 0.007836900651454927 0.02041235938668251 0.015017854049801825 49.01087333400631 45.0 0.0 no 10991 chrXIII_890982 28861 essential YMR308C 1220 - TTACCATATCCAGGATTTTT V|413|L V|413|I M|412|I M|412|I PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 0.5811006981406833 P32337 0.9539830088615416 0.9574310183525084 0.9553959965705872 0.9553959965705872 0.048392754048109055 0.475184440612793 0.2211611121892929 0.2211611121892929 44.8239584154702 30.0 0.0 no 10992 chrXIII_891025 28862 essential YMR308C 1177 - AGCACAACCCTCAGCTGCAG A|399|P A|399|T C|398|S C|398|Y PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 -0.4263779408948143 P32337 0.9573720097541808 0.9523990154266356 0.9421560168266296 0.9290120005607604 0.27744388580322266 0.5660769939422607 0.20998626947402954 0.0046573285944759854 57.138269366040156 60.0 0.0 no 10993 chrXIII_890985r 28863 essential YMR308C 1214 + GATCCCAAAAATCCTGGATA I|406|M silent|ATC>ATT|I|406 P|407|A P|407|S PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 -0.4243597181634275 P32337 0.9598389863967896 0.9562489986419678 0.9498909711837769 0.056848455220460885 0.7187250256538391 1.0 44.07429917014184 40.0 0.0 no 10994 chrXIII_891235 28867 essential YMR308C 967 - TGCTGCATCATCATCATCTA A|329|P A|329|T A|328|P A|328|T PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 0.6921955996502376 P32337 0.9573720097541808 0.9523990154266356 0.9573720097541808 0.9523990154266356 0.145143061876297 0.2475263625383377 0.08643917739391327 0.20084315538406367 49.01825419139823 40.0 0.0 no 10995 chrXIII_891285r 28868 essential YMR308C 914 + TTACGGGCAAACTTTAGTGA Y|306|* silent|TAC>TAT|Y|306 PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 -0.7476251610748887 P32337 43.40749680358715 40.0 0.0 no 10996 chrXIII_891518 28869 essential YMR308C 684 - TTACCATCATCTAAAAATCT G|234|A G|234|D G|234|R G|234|S PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 0.3406426678807135 P32337 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.13261809945106506 0.4829603135585785 0.19966650009155276 0.3282574713230133 36.362409392355396 25.0 0.0 no 10997 chrXIII_891521r 28870 essential YMR308C 678 + TTACCAAGATTTTTAGATGA P|228|A P|228|S P|228|R P|228|L PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 1.0904919640255597 P32337 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.0 0.0 0.0 0.0 37.365373149477136 25.0 0.0 no 10998 chrXIII_891575 28871 essential YMR308C 627 - AACTTGGACCACTCAGATTT K|215|N silent|AAG>AAA|K|215 PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 -0.28047062334206163 P32337 0.9355990290641784 0.5101386308670044 45.76917754343833 40.0 0.0 no 10999 chrXIII_891583r 28872 essential YMR308C 616 + AGCAACTACCAAAATCTGAG Q|207|E Q|207|* L|208|V silent|CTA>TTA|L|208 PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 -1.6576013570996877 P32337 0.9590039849281312 0.9512209892272948 1.0 0.1688276380300522 0.7842000126838684 39.93654640071867 40.0 0.0 no 11000 chrXIII_891614r 28873 essential YMR308C 585 + GCTGCAGTTACGGCTTTCGT A|196|G A|196|V A|197|G A|197|V PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 -0.4328216444627431 P32337 0.9484469890594482 0.9504740238189696 0.9484469890594482 0.9504740238189696 0.24873678386211395 0.03313974663615227 0.0313059575855732 0.024768484756350517 56.97704599770338 55.00000000000001 0.0 no 11001 chrXIII_891701 28876 essential YMR308C 501 - TCAACAGCGGTAATTAAATA D|174|H D|174|N V|173|L V|173|I PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 0.9848091485762956 P32337 0.9486550092697144 0.956179976463318 0.9539830088615416 0.9574310183525084 0.4760540127754211 1.0 0.64369136095047 0.4138223230838776 36.43103975760522 30.0 0.0 no 11002 chrXIII_891743 28877 essential YMR308C 459 - AAACTGGATTCTCTAAAATT S|159|T S|159|N PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 1.3231695355955315 P32337 0.9512869715690612 0.9536849856376648 0.2679027616977692 0.07198464870452881 33.89528717159294 25.0 0.0 no 11003 chrXIII_891744 28879 essential YMR308C 458 - AACTGGATTCTCTAAAATTT S|159|T S|159|N PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 -0.13887885741001246 P32337 0.9512869715690612 0.9536849856376648 0.2679027616977692 0.07198464870452881 35.30222712400837 25.0 0.0 no 11004 chrXIII_891811r 28880 essential YMR308C 388 + TTCAAGACGACTTACCAGCA Q|131|E Q|131|* PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 -0.20115939700622668 P32337 0.9590039849281312 0.3801422715187073 46.914776480224475 45.0 0.0 no 11005 chrXIII_891896r 28881 essential YMR308C 303 + ATTCGTTCTTCATTGTTAAA R|103|G R|103|C PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 0.5033395893368329 P32337 0.8994590044021606 0.8926740288734436 0.016550157219171524 0.002352273790165782 39.235614004971865 25.0 0.0 no 11006 chrXIII_891937 28882 essential YMR308C 265 - CCTAATATGTGTGATATTTT R|95|T R|95|K PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 0.4892895905205918 P32337 0.932735025882721 0.955805003643036 0.3554728329181671 0.5573919415473938 38.721530254089934 25.0 0.0 no 11007 chrXIII_891937r 28883 essential YMR308C 262 + CCAAAAATATCACACATATT silent|TCC>TCG|S|88 silent|TCC>TCT|S|88 PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 0.16317664985623348 P32337 34.51293749551621 25.0 0.0 no 11008 chrXIII_892026 28884 essential YMR308C 176 - ATGCTGCAACTGTTGTATCT A|65|P A|65|T A|64|P A|64|T PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 0.371808076895676 P32337 0.9573720097541808 0.9523990154266356 0.9573720097541808 0.9523990154266356 0.056515388190746314 0.4019821286201477 0.1122104823589325 0.1625545173883438 4.88640022277832 0.7635999321937561 48.077694367810466 40.0 0.0 no 11009 chrXIII_892027 28885 essential YMR308C 175 - TGCTGCAACTGTTGTATCTT A|65|P A|65|T A|64|P A|64|T PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 0.0254971205676143 P32337 0.9573720097541808 0.9523990154266356 0.9573720097541808 0.9523990154266356 0.056515388190746314 0.4019821286201477 0.1122104823589325 0.1625545173883438 4.88640022277832 0.7635999321937561 48.37111150378729 40.0 0.0 no 11010 chrXIII_892170r 28887 essential YMR308C 29 + AACATTACTTCAGATTGTCC T|11|R T|11|I PSE1 Protein Secretion Enhancer 1089.0 0 0 0 0 0.17010091889519482 P32337 0.9476869702339172 0.9472420215606691 0.09664107114076614 0.13222377002239227 42.82693569196954 35.0 0.0 no 11011 chrXIII_893744 28889 essential YMR309C 1663 - TTCAATCAAACATAATTTAA E|561|Q E|561|K L|559|F silent|TTG>TTA|L|559 NIP1 Nuclear ImPort 812.0 0 0 0 0 0.4473817939840583 P32497 0.956179976463318 0.9475290179252625 0.9587849974632264 0.5871948599815369 0.9215191602706908 0.026836685836315155 29.20210325806187 15.0 0.0 no 11012 chrXIII_893747 28890 essential YMR309C 1660 - AATCAAACATAATTTAAAGG L|559|F silent|TTG>TTA|L|559 NIP1 Nuclear ImPort 812.0 0 0 0 0 0.018638110299910467 P32497 0.9587849974632264 0.026836685836315155 28.18413267972033 20.0 0.0 no 11013 chrXIII_893791r 28891 essential YMR309C 1613 + CCTACAAATTTTATTCAACA L|539|V silent|CTA>TTA|L|539 Q|540|E Q|540|* NIP1 Nuclear ImPort 812.0 0 0 0 0 0.17875430474403908 P32497 0.9512209892272948 0.9590039849281312 0.5058759450912476 0.01347176358103752 36.69626636677333 25.0 0.0 no 11014 chrXIII_893792r 28892 essential YMR309C 1612 + CCCTACAAATTTTATTCAAC L|539|V silent|CTA>TTA|L|539 silent|TCC>TCG|S|538 silent|TCC>TCT|S|538 NIP1 Nuclear ImPort 812.0 0 0 0 0 0.4342110275640453 P32497 0.9512209892272948 0.5058759450912476 39.07601847006924 30.0 0.0 no 11015 chrXIII_893933 28893 essential YMR309C 1474 - AACAGCAATGTTGTTTTGCT V|498|L V|498|I A|497|P A|497|T NIP1 Nuclear ImPort 812.0 0 1 0 0 -1.2189245907341997 P32497 0.9539830088615416 0.9574310183525084 0.9573720097541808 0.9523990154266356 0.7069900035858154 0.4280967116355896 0.09016437828540802 0.2141474187374115 44.50578903264966 35.0 0.0 no 11016 chrXIII_894115r 28894 essential YMR309C 1289 + ACGTCCATTCGTCAAGAGAT R|431|G R|431|C P|432|A P|432|S NIP1 Nuclear ImPort 812.0 0 0 0 0 -1.2856937769623131 P32497 0.8994590044021606 0.8926740288734436 0.9562489986419678 0.9498909711837769 0.022750727832317352 0.004011050797998904 0.3029695451259613 0.032255403697490685 47.78983971559563 45.0 0.0 no 11017 chrXIII_894240 28896 essential YMR309C 1167 - ATCAAATAATCACTGGAATG L|395|F silent|TTG>TTA|L|395 NIP1 Nuclear ImPort 812.0 0 0 0 0 -0.6407751194636904 P32497 0.9587849974632264 0.012010823003947737 33.94114544322463 30.0 0.0 no 11018 chrXIII_894589r 28899 essential YMR309C 815 + ACAATCCTTGATTTCTACTT Q|273|E Q|273|* S|274|C S|274|F NIP1 Nuclear ImPort 812.0 0 0 0 0 -0.5365195791888764 P32497 0.9590039849281312 0.945252001285553 0.9294660091400146 1.0 0.0005678760935552418 0.0018301662057638168 42.85499086133706 30.0 0.0 no 11019 chrXIII_894693r 28900 essential YMR309C 711 + TTCACAATTTCTTCGTCTCA F|238|L silent|TTC>TTT|F|238 T|239|R T|239|I NIP1 Nuclear ImPort 812.0 0 0 0 0 0.2972165224038969 P32497 0.9387490153312684 0.9476869702339172 0.9472420215606691 0.2314605265855789 0.4227816462516785 0.1520640254020691 45.474414118477746 35.0 0.0 no 11020 chrXIII_894890 28901 essential YMR309C 517 - ATTCACAGCGTCCTCCACTT silent|GTG>GTC|V|178 silent|GTG>GTA|V|178 V|178|L V|178|M NIP1 Nuclear ImPort 812.0 0 0 0 1 -2.217066457002546 P32497 0.9539830088615416 0.9587630033493042 0.9869860410690308 0.2843969166278839 56.41492687070632 50.0 0.0 yes 11021 chrXIII_895191 28906 essential YMR309C 216 - TCAGATTTCTTGAACCAGTC E|79|Q E|79|K NIP1 Nuclear ImPort 812.0 0 0 0 0 -0.7124446666477241 P32497 0.956179976463318 0.9475290179252625 0.4098758399486542 0.7001513242721558 45.26310401830585 40.0 0.0 no 11022 chrXIII_895364 28907 essential YMR309C 43 - ATCTTCTTCGGATGAAGAAC D|21|H D|21|N E|20|Q E|20|K NIP1 Nuclear ImPort 812.0 0 0 0 0 -5.6753541941200725 P32497 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.058813463896512985 0.13672775030136108 0.3992461860179901 0.5566408634185791 41.116384534894564 40.0 0.0 yes 11023 chrXIII_901736 28909 essential YMR314W 27 + ACAGTCACTTTTTCTCCTAC T|10|R T|10|I silent|GTC>GTG|V|11 silent|GTC>GTT|V|11 PRE5 PRoteinase yscE 234.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.34101492342057504 P40302 0.02237752825021744 0.3223256468772888 3.735460042953491 -0.1747799962759018 48.86259308479674 40.0 1.0 no 11024 chrXIII_901753 28911 essential YMR314W 44 + TACAGGCCGTCTGTTCCAAG T|16|R T|16|I silent|GGC>GGG|G|17 silent|GGC>GGT|G|17 PRE5 PRoteinase yscE 234.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.9224973034018332 P40302 0.10445796698331833 0.036849845200777054 -1.0062400102615356 -1.0297000408172607 54.32897763400405 55.00000000000001 1.0 no 11025 chrXIII_901768r 28913 essential YMR314W 62 - CTTCCAAGGCGTATTCCACT E|27|Q E|27|K L|26|F silent|TTG>TTA|L|26 PRE5 PRoteinase yscE 234.0 0 1 0 0 -0.7536140949070819 P40302 0.043240122497081764 0.122672438621521 0.0498264767229557 -0.3310399949550629 -0.7428799867630005 1.280500054359436 1.5118000507354736 53.627009178584785 50.0 1.0 no 11026 chrXIII_901782 28915 essential YMR314W 73 + CCTTGGAAGCTATTAAACAA silent|GCC>GCG|A|25 silent|GCC>GCT|A|25 PRE5 PRoteinase yscE 234.0 0 0 0 0 0.8685515884862176 P40302 39.59353848060982 35.0 1.0 no 11027 chrXIII_901782r 28918 essential YMR314W 76 - CCCTTGTTTAATAGCTTCCA G|32|R G|32|R G|32|A G|32|E PRE5 PRoteinase yscE 234.0 0 1 0 0 -3.6664939277151127 P40302 0.0 0.0 0.0 0.0 11.976759910583494 11.976759910583494 1.914800047874451 6.866179943084718 44.59724044799805 44.59724044799805 6.082499980926514 29.25861930847168 51.25008969220852 40.0 1.0 yes 11028 chrXIII_901897 28919 essential YMR314W 188 + CATCAAATGTGACGAGCACA I|64|M silent|ATC>ATT|I|64 PRE5 PRoteinase yscE 234.0 0 0 0 0 0.9235500640605688 P40302 0.02761713974177837 0.11531999707221985 -0.08708000183105469 43.27285923067411 45.0 1.0 no 11029 chrXIII_901943r 28924 essential YMR314W 237 - TTACTTAAAACTCTAGCATC S|85|T S|85|N PRE5 PRoteinase yscE 234.0 0 0 0 0 0.4701598426229872 P40302 0.4387218356132507 0.06705322116613388 -0.3668000102043152 1.2657999992370603 36.93678027448459 30.0 1.0 no 11030 chrXIII_902087r 28928 essential YMR314W 381 - ATCAACAAACCAACACCGTA L|133|F silent|TTG>TTA|L|133 L|132|F silent|TTG>TTA|L|132 PRE5 PRoteinase yscE 234.0 0 0 0 0 -0.6157555457499809 P40302 0.004439939744770528 0.14328499138355255 6.9395599365234375 5.770500183105469 42.39628644370208 40.0 1.0 no 11031 chrXIII_902171 28930 essential YMR314W 462 + GAACTATATGGTACAGCTAT L|156|V silent|CTA>TTA|L|156 PRE5 PRoteinase yscE 234.0 0 0 0 0 -0.9233570478247166 P40302 0.3132624924182892 -0.37992000579833984 -0.16354000568389893 41.115710426696864 35.0 1.0 no 11032 chrXIV_40769r 28934 essential YNL317W 153 - TCTGGCTCTACCACTAGGTT E|58|Q E|58|K E|56|D silent|GAG>GAA|E|56 PFS2 Polyadenylation Factor Subunit 465.0 0 0 0 0 -0.5891150702460439 P42841 0.956179976463318 0.9475290179252625 0.94931298494339 0.030422825366258618 0.06855269521474837 0.01966792903840542 55.41219347533064 50.0 1.0 no 11033 chrXIV_40787r 28935 essential YNL317W 171 - TCTATTGTGTATGAAGTTTC D|64|H D|64|N PFS2 Polyadenylation Factor Subunit 465.0 0 0 0 0 -0.35257439763628184 P42841 0.9486550092697144 0.956179976463318 0.048176296055316925 0.2753541171550751 39.561642491645046 30.0 1.0 no 11034 chrXIV_40814 28936 essential YNL317W 195 + ATGCCGCCTAATGCCTACAG P|67|A P|67|S P|67|R P|67|L PFS2 Polyadenylation Factor Subunit 465.0 0 0 0 0 -0.6051196112518948 P42841 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.03137626126408577 0.05692755430936813 0.010208106599748136 0.08847596496343613 54.831373041014395 55.00000000000001 1.0 no 11035 chrXIV_40820r 28938 essential YNL317W 204 - TCTCGACCTCTGTAGGCATT R|74|P R|74|Q D|75|H D|75|N PFS2 Polyadenylation Factor Subunit 465.0 0 0 0 0 -0.5192971143755949 P42841 0.9099509716033936 0.949662983417511 0.9486550092697144 0.956179976463318 0.2301260232925415 0.5081588625907898 0.016209769994020462 1.0 54.345362826161356 50.0 1.0 no 11036 chrXIV_40827r 28939 essential YNL317W 211 - GACTCGATCTCGACCTCTGT V|77|L V|77|I R|76|P R|76|Q PFS2 Polyadenylation Factor Subunit 465.0 0 0 0 0 0.6179783110747595 P42841 0.9539830088615416 0.9574310183525084 0.9099509716033936 0.949662983417511 0.32738375663757324 0.4719900488853455 1.0 0.4343450963497162 53.76630563251399 55.00000000000001 1.0 no 11037 chrXIV_40907r 28941 essential YNL317W 291 - TCTGGGGTCCATTGGATGGC E|104|Q E|104|K PFS2 Polyadenylation Factor Subunit 465.0 0 0 0 0 -1.834643988966808 P42841 0.956179976463318 0.9475290179252625 0.010003248229622841 0.0094794612377882 58.33627972350979 60.0 1.0 no 11038 chrXIV_40908r 28942 essential YNL317W 292 - TTCTGGGGTCCATTGGATGG E|104|Q E|104|K PFS2 Polyadenylation Factor Subunit 465.0 0 0 0 0 -0.5796473086084966 P42841 0.956179976463318 0.9475290179252625 0.010003248229622841 0.0094794612377882 54.70244489791929 55.00000000000001 1.0 no 11039 chrXIV_40911r 28944 essential YNL317W 295 - GCCTTCTGGGGTCCATTGGA G|105|R G|105|S G|105|A G|105|D PFS2 Polyadenylation Factor Subunit 465.0 0 0 0 0 -2.302950519526813 P42841 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 61.87323573341507 60.0 1.0 yes 11040 chrXIV_41005 28946 essential YNL317W 386 + CCTCATGCAAGCACATGATT silent|CTC>CTG|L|130 silent|CTC>CTT|L|130 L|130|V L|130|F PFS2 Polyadenylation Factor Subunit 465.0 0 0 0 0 -1.6866349432133152 P42841 0.9512209892272948 0.9587849974632264 0.012608546763658524 0.0045956801623106 48.73227046318539 45.0 1.0 no 11041 chrXIV_41139 28950 essential YNL317W 520 + CTGCACACACGGAAAGTATT A|175|G A|175|V H|176|D H|176|Y PFS2 Polyadenylation Factor Subunit 465.0 0 0 0 0 0.5194788403694982 P42841 0.9484469890594482 0.9504740238189696 0.9473130106925964 0.9489949941635132 0.334506630897522 0.030140919610857964 0.00911595858633518 0.0023209271021187305 44.08612930196477 45.0 1.0 no 11042 chrXIV_41108r 28951 essential YNL317W 492 - TCTTTAACCATACTAAAGTT E|171|Q E|171|K PFS2 Polyadenylation Factor Subunit 465.0 0 0 0 0 0.43347232898209576 P42841 0.956179976463318 0.9475290179252625 0.4604934751987457 0.5492721199989319 37.277391327508674 25.0 1.0 no 11043 chrXIV_41146 28953 essential YNL317W 527 + CACGGAAAGTATTAGGGATA T|177|R T|177|M PFS2 Polyadenylation Factor Subunit 465.0 0 0 0 0 -0.0637878484572339 P42841 0.9476869702339172 0.9502379894256592 0.19389480352401733 0.01742686703801155 40.26622456022147 40.0 1.0 no 11044 chrXIV_41272r 28955 essential YNL317W 656 - CACAACTTTTCACGTCCCAG C|225|S C|225|Y S|224|T S|224|N PFS2 Polyadenylation Factor Subunit 465.0 0 0 0 0 -0.127546817322112 P42841 0.9421560168266296 0.9290120005607604 0.9512869715690612 0.9536849856376648 0.00585267785936594 0.0019173894543200727 0.07030700892210008 0.021858248859643936 50.08516851096072 50.0 1.0 no 11045 chrXIV_41325r 28956 essential YNL317W 709 - TACTAAATTGTCCTTAGATG V|243|L V|243|I PFS2 Polyadenylation Factor Subunit 465.0 0 1 0 0 0.3626541832556751 P42841 0.9539830088615416 0.9574310183525084 0.20783871412277224 0.9031118154525756 37.833431134928105 30.0 1.0 no 11046 chrXIV_41485 28958 essential YNL317W 866 + CGACATTAGATACAGTATGA D|290|E silent|GAC>GAT|D|290 PFS2 Polyadenylation Factor Subunit 465.0 0 0 0 0 0.27698840174861794 P42841 0.9532920122146606 0.0 38.936797334731295 35.0 1.0 no 11047 chrXIV_41576 28959 essential YNL317W 957 + TTCACTCTGGCGTGCTATGA F|320|L silent|TTC>TTT|F|320 T|321|S T|321|I PFS2 Polyadenylation Factor Subunit 465.0 0 0 0 0 0.1753788518592776 P42841 0.9387490153312684 0.9491789937019348 0.9472420215606691 0.2512190639972687 0.47024881839752203 0.2672177851200104 52.98214554569103 50.0 1.0 no 11048 chrXIV_45970r 28963 essential YNL313C 2030 + GAGCGCTGCATATACGAAAA S|678|R silent|AGC>AGT|S|678 A|679|G A|679|V EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 -0.219142214320166 P42842 0.9417110085487366 0.9484469890594482 0.9504740238189696 0.008344906382262707 0.024526376277208328 0.02139048650860786 43.19525876172258 45.0 0.0 no 11049 chrXIV_46102 28965 essential YNL313C 1901 - ACCACGTTTCAAAGCTTAAT W|640|S W|640|* W|640|C W|640|* EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 -2.3829197281858736 P42842 0.8858469724655151 0.8858469724655151 0.0 0.0 42.66559251898576 35.0 0.0 yes 11050 chrXIV_46152 28966 essential YNL313C 1851 - TTCAAGGTAGCAGAGTAATT L|623|F silent|TTG>TTA|L|623 EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 0.6181096334062632 P42842 0.9587849974632264 0.02594535239040852 41.61594710763779 35.0 0.0 no 11051 chrXIV_46293r 28968 essential YNL313C 1707 + GCCAGGGCTTACTCCATTTT silent|GCC>GCG|A|570 silent|GCC>GCT|A|570 A|570|G A|570|V EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 0.2868346584314571 P42842 0.9484469890594482 0.9504740238189696 0.0 0.0 57.506621224407645 50.0 0.0 no 11052 chrXIV_46327 28969 essential YNL313C 1676 - TTTCATTTATTCTTTGAAGA E|565|Q E|565|K EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 0.9553837790655773 P42842 0.956179976463318 0.9475290179252625 0.5606626868247986 0.8987236618995667 36.27412857610125 20.0 0.0 no 11053 chrXIV_46418 28971 essential YNL313C 1585 - TCTTTCATAAATTTCCACAG R|535|T R|535|K E|534|Q E|534|K EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 -0.06470895906966319 P42842 0.932735025882721 0.955805003643036 0.956179976463318 0.9475290179252625 0.02159394323825836 0.09228695929050446 0.0 0.0 39.78422631202756 30.0 0.0 no 11054 chrXIV_46452r 28972 essential YNL313C 1548 + GCTGAAAAATATATGTCGCT A|517|G A|517|V EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 0.6220109200470119 P42842 0.9484469890594482 0.9504740238189696 0.0 0.0 39.358650823907 35.0 0.0 no 11055 chrXIV_46457 28974 essential YNL313C 1546 - CGACATATATTTTTCAGCTA M|521|I M|521|I EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 0.6974300139207057 P42842 0.9553959965705872 0.9553959965705872 0.5557274222373962 0.5557274222373962 40.653037787852156 30.0 0.0 no 11056 chrXIV_46480 28975 essential YNL313C 1523 - TGGCATCCAATTGCCACCTA A|514|P A|514|T D|513|H D|513|N EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 0.2871641305041248 P42842 0.9573720097541808 0.9523990154266356 0.9486550092697144 0.956179976463318 0.24362026154994965 0.7872716188430786 0.0 0.0 55.17493119270807 50.0 0.0 no 11057 chrXIV_46493r 28977 essential YNL313C 1507 + AGCTGCCGTTCATCCCTAGG L|504|V silent|CTG>TTG|L|504 P|505|A P|505|S EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 -0.9027876708589802 P42842 0.9512209892272948 0.9562489986419678 0.9498909711837769 0.05344631895422936 0.4507337808609009 0.6119447350502014 60.89867001519855 60.0 0.0 no 11058 chrXIV_46496r 28979 essential YNL313C 1504 + ACCAGCTGCCGTTCATCCCT Q|503|E Q|503|* H|502|Q silent|CAC>CAT|H|502 EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 -1.5030154052972398 P42842 0.9590039849281312 0.9588389992713928 0.2591909468173981 0.161928191781044 63.981179763119776 60.0 0.0 no 11059 chrXIV_46542 28981 essential YNL313C 1461 - ACATTGATTTCGCTTGAACT V|494|L V|494|I EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 0.3303499680445805 P42842 0.9539830088615416 0.9574310183525084 0.5597756505012512 0.4904334545135498 42.916258945041754 35.0 0.0 no 11060 chrXIV_46585 28982 essential YNL313C 1418 - TCAAATCCAATTCTTCTACG L|479|F silent|TTG>TTA|L|479 D|478|H D|478|N EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 -0.01857817704051179 P42842 0.9587849974632264 0.9486550092697144 0.956179976463318 0.1648818999528885 0.15099860727787018 0.20972193777561188 40.61248774454213 35.0 0.0 no 11061 chrXIV_46664 28985 essential YNL313C 1339 - TGACCTTTCCCATAATGATC R|452|S silent|AGG>AGA|R|452 R|452|T R|452|K EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 0.6242893833842629 P42842 0.9087679982185364 0.932735025882721 0.955805003643036 0.0 0.0 0.0 47.04329781496534 40.0 0.0 no 11062 chrXIV_46755 28987 essential YNL313C 1248 - TCCACAAGAGGATCCTTGGC silent|GTG>GTC|V|422 silent|GTG>GTA|V|422 E|423|Q E|423|K EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 -0.2016262784591477 P42842 0.956179976463318 0.9475290179252625 0.4417844414710999 0.30208754539489746 53.457550224072286 55.00000000000001 0.0 no 11063 chrXIV_46918 28989 essential YNL313C 1085 - CTTCTTCATAACCTTCATTT E|368|Q E|368|K E|367|Q E|367|K EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 -0.18239168986151813 P42842 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.3325743079185486 0.4507750570774078 0.3412461280822754 0.5048707723617554 43.75408890271024 30.0 0.0 no 11064 chrXIV_46973 28990 essential YNL313C 1030 - GTCTAGAGGTTCATCAGCAA D|350|H D|350|N EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 0.09975526428151506 P42842 0.9486550092697144 0.956179976463318 0.3337726294994354 0.4777576327323914 49.008911694747326 45.0 0.0 no 11065 chrXIV_47072 28992 essential YNL313C 931 - AGCAAAATTTTGAAATGTGA A|317|P A|317|T EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 0.2561473086691353 P42842 0.9573720097541808 0.9523990154266356 0.2714708745479584 0.5671299695968628 33.423319097547115 25.0 0.0 no 11066 chrXIV_47216 28997 essential YNL313C 787 - GCACAAATGTTCTGTGTTGA L|268|F silent|TTG>TTA|L|268 C|269|S C|269|Y EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 0.32870164470596697 P42842 0.9587849974632264 0.9421560168266296 0.9290120005607604 0.07183216512203218 0.09731093794107436 0.01915098913013935 44.992343239603365 40.0 0.0 no 11067 chrXIV_47320 28998 essential YNL313C 683 - CCTTAGTTATCGCATATGCA K|234|N silent|AAG>AAA|K|234 EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 -0.5146024587056299 P42842 0.9355990290641784 0.4698757529258728 48.44330848627635 40.0 0.0 no 11068 chrXIV_47320r 28999 essential YNL313C 680 + CCTTGCATATGCGATAACTA L|228|V L|228|F A|229|G A|229|V EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 0.16241176366396556 P42842 0.9512209892272948 0.9587849974632264 0.9484469890594482 0.9504740238189696 1.0 0.01985154300928116 0.3912040591239929 0.2998523712158203 45.220606955096684 40.0 0.0 no 11069 chrXIV_47359 29000 essential YNL313C 644 - TTGCAGATGCAACACTAGCT A|221|P A|221|T EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 -1.4295224032161986 P42842 0.9573720097541808 0.9523990154266356 0.30201590061187744 0.6201757192611694 48.16304295908577 45.0 0.0 no 11070 chrXIV_47376 29001 essential YNL313C 627 - GCTTGGAACCCAGAAGGTTC A|216|P A|216|T EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 0.34873536647758685 P42842 0.9573720097541808 0.9523990154266356 0.11036565154790877 1.0 52.35626777598941 55.00000000000001 0.0 no 11071 chrXIV_47460r 29003 essential YNL313C 540 + ATCTCTGCTGAGTCTACTCC I|181|M silent|ATC>ATT|I|181 S|182|C S|182|F EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 -0.4716948606337941 P42842 0.9598389863967896 0.945252001285553 0.9294660091400146 0.20353029668331146 0.053942184895277016 0.060312617570161826 54.42155346807914 50.0 0.0 no 11072 chrXIV_47489 29006 essential YNL313C 514 - TAGCGGAATTTCTTGATCCG silent|CCG>CCC|P|177 silent|CCG>CCA|P|177 EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 0.7848463257164962 P42842 46.419680688093536 45.0 0.0 no 11073 chrXIV_47506r 29007 essential YNL313C 494 + AAGCTTATTTGATGTTACCC S|166|R silent|AGC>AGT|S|166 EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 0.11208351843768594 P42842 0.9417110085487366 0.2929741442203522 45.02004737983651 35.0 0.0 no 11074 chrXIV_47543r 29008 essential YNL313C 457 + TATCACTATTATTACTTGAA S|154|* S|154|L L|155|V silent|CTA>TTA|L|155 EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 0.210632149805991 P42842 0.9298099875450134 0.9512209892272948 0.013626812025904655 1.0 34.29754336310157 20.0 0.0 no 11075 chrXIV_47583 29009 essential YNL313C 420 - TCATCCATAAATTCGTAGGC D|147|H D|147|N D|146|H D|146|N EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 1.1816029987240149 P42842 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.550704300403595 0.37658342719078064 0.09679953753948213 0.2683186233043671 44.611326914179365 40.0 0.0 no 11076 chrXIV_47587r 29011 essential YNL313C 413 + CCAGCCTGCCTACGAATTTA Q|139|E Q|139|* P|140|A P|140|S EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 -0.05547396014990622 P42842 0.9590039849281312 0.9562489986419678 0.9498909711837769 0.5582870244979858 0.7073976993560791 0.695803165435791 53.083268939014424 50.0 0.0 no 11077 chrXIV_47781r 29016 essential YNL313C 219 + AACGTTGAGGTTTTCAAAAT N|74|K silent|AAC>AAT|N|74 EMW1 Essential for Maintenance of the cell Wall 904.0 0 0 0 0 0.4401732874798409 P42842 0.9439849853515624 0.9064943194389344 37.37558867432 30.0 0.0 no 11078 chrXIV_52016r 29019 essential YNL310C 393 + GAACAAGTTAGCCAAGACGT Q|133|E Q|133|* ZIM17 ZInc finger Motif protein of 17 kDa 174.0 0 0 0 0 -1.6566571488449395 P42844 0.9590039849281312 1.0 0.014379999600350857 44.28116790652729 45.0 0.0 no 11079 chrXIV_52150 29020 essential YNL310C 262 - ACCTTTCTCGTACGCCTGCT G|94|R G|94|S G|94|A G|94|D ZIM17 ZInc finger Motif protein of 17 kDa 174.0 0 0 0 0 -2.205922303239035 P42844 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 27.890399932861328 14.669300079345705 8.701299667358397 27.72792053222656 58.905184541458254 55.00000000000001 0.0 yes 11080 chrXIV_52285 29025 essential YNL310C 127 - TTCATTATGTGCGATGATAT E|49|Q E|49|K ZIM17 ZInc finger Motif protein of 17 kDa 174.0 0 0 0 0 0.8830623562528221 P42844 0.956179976463318 0.9475290179252625 0.23777174949646 0.3009195923805237 40.759850258618776 30.0 0.0 no 11081 chrXIV_52351 29028 essential YNL310C 61 - TACGCGAGGCGCCCAACATC V|27|L V|27|I R|26|P R|26|H ZIM17 ZInc finger Motif protein of 17 kDa 174.0 0 0 0 0 -0.6560034810452774 P42844 0.9539830088615416 0.9574310183525084 0.9099509716033936 0.9570810198783876 0.7954024672508241 0.4900872707366944 0.2871276140213013 0.14825119078159332 56.04418102211059 65.0 0.0 no 11082 chrXIV_52363r 29030 essential YNL310C 46 + CCAGGTACTTTGCCAGATGT silent|ACC>ACG|T|16 silent|ACC>ACT|T|16 ZIM17 ZInc finger Motif protein of 17 kDa 174.0 0 0 0 0 0.1584754235882686 P42844 54.412316788843384 50.0 0.0 no 11083 chrXIV_54705r 29032 essential YNL308C 1170 + GACTTTTATGCAGACGCCGA D|391|E silent|GAC>GAT|D|391 KRI1 KRR1-Interacting protein 591.0 0 0 0 0 0.04751345871296514 P42846 0.9532920122146606 1.0 50.37122549501528 50.0 0.0 no 11084 chrXIV_54738 29035 essential YNL308C 1140 - TCGTCATCCTCGTTCCAGGT E|387|Q E|387|K D|386|H D|386|N KRI1 KRR1-Interacting protein 591.0 0 0 0 0 -0.4461274349558095 P42846 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.3693018853664398 0.2643501460552216 0.1626790016889572 0.7915136218070984 59.503224385756205 55.00000000000001 0.0 no 11085 chrXIV_54868r 29036 essential YNL308C 1007 + TGCTGAAATTAATGCCGACA A|337|G A|337|V KRI1 KRR1-Interacting protein 591.0 0 0 0 0 0.4793179287663637 P42846 0.9484469890594482 0.9504740238189696 0.2852572500705719 0.15496712923049927 42.93037118675272 40.0 0.0 no 11086 chrXIV_55191 29040 essential YNL308C 687 - ATCACCTTGTCCCCCTTCTT silent|GTG>GTC|V|235 silent|GTG>GTA|V|235 V|235|L V|235|M KRI1 KRR1-Interacting protein 591.0 0 0 0 0 -0.21827673790934046 P42846 0.9539830088615416 0.9587630033493042 0.2994807362556457 0.1049048975110054 61.88127888214694 50.0 0.0 no 11087 chrXIV_55204r 29041 essential YNL308C 671 + ACAGGCCTGGATTCCTAAGA Q|225|E Q|225|* A|226|G A|226|V KRI1 KRR1-Interacting protein 591.0 0 0 0 0 -0.7083133120164861 P42846 0.9590039849281312 0.9484469890594482 0.9504740238189696 0.07314195483922957 0.14111100137233734 0.011010576970875263 52.356267775989295 50.0 0.0 no 11088 chrXIV_55254 29042 essential YNL308C 624 - TCTTCATTTACGGTTGGATC E|215|Q E|215|K E|214|Q E|214|K KRI1 KRR1-Interacting protein 591.0 0 0 0 0 -0.1027533958088527 P42846 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.315232515335083 0.14378400146961212 0.344139039516449 0.24276934564113614 46.052519358523 40.0 0.0 no 11089 chrXIV_55352 29044 essential YNL308C 526 - TTCATTTTCTTCATCGCTAA E|182|Q E|182|K KRI1 KRR1-Interacting protein 591.0 0 1 0 0 0.343974120694588 P42846 0.956179976463318 0.9475290179252625 0.098930686712265 0.08626450598239899 43.510376710353405 30.0 0.0 no 11090 chrXIV_55440r 29045 essential YNL308C 435 + TACGAACATGCAACTGTTGA Y|146|* silent|TAC>TAT|Y|146 H|148|D H|148|Y KRI1 KRR1-Interacting protein 591.0 0 0 0 0 -0.8626149739426311 P42846 0.9473130106925964 0.9489949941635132 0.6454750895500183 0.6663214564323425 41.706026868604 40.0 0.0 no 11091 chrXIV_55463 29046 essential YNL308C 415 - TTCTTCGTCATCCTCCTTTA E|145|Q E|145|K E|144|Q E|144|K KRI1 KRR1-Interacting protein 591.0 0 0 0 0 -0.0015713039075645194 P42846 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.30703288316726685 0.3127574324607849 0.1678554117679596 0.04252981022000313 53.242905215466116 40.0 0.0 no 11092 chrXIV_55477r 29048 essential YNL308C 398 + ACTTTCTGGTGATGCCTTAA L|134|V L|134|F S|135|C S|135|F KRI1 KRR1-Interacting protein 591.0 0 0 0 0 -0.020049068419950758 P42846 0.9512209892272948 0.9587849974632264 0.945252001285553 0.9294660091400146 0.0 0.0 0.06082788109779357 0.05329667776823044 48.48210192852736 40.0 0.0 no 11093 chrXIV_55544r 29049 essential YNL308C 331 + CCAAACTGGCCAATCGTGAG silent|GCC>GCG|A|111 silent|GCC>GCT|A|111 L|113|V silent|CTG>TTG|L|113 KRI1 KRR1-Interacting protein 591.0 0 0 0 0 -0.5466671604905178 P42846 0.9512209892272948 0.3916603624820709 48.7917007263589 55.00000000000001 0.0 no 11094 chrXIV_55584 29051 essential YNL308C 294 - TCCTCGAAGAATTTGACTTT E|104|D silent|GAG>GAA|E|104 D|105|H D|105|N KRI1 KRR1-Interacting protein 591.0 0 0 0 0 0.8886720457184087 P42846 0.94931298494339 0.9486550092697144 0.956179976463318 0.5323221087455751 0.010799339041113852 0.03471484035253525 42.15413294603468 35.0 0.0 no 11095 chrXIV_55585r 29052 essential YNL308C 290 + TCCTAAAGTCAAATTCTTCG P|98|R P|98|L P|98|A P|98|S KRI1 KRR1-Interacting protein 591.0 0 0 0 0 0.04039937345499784 P42846 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.05736417695879936 0.02111705206334591 0.09569581598043443 0.4718461036682129 39.91662778878185 35.0 0.0 no 11096 chrXIV_58167r 29056 essential YNL306W 15 - CATCGGCAGCCTTTCCAAAC R|11|P R|11|Q C|10|S C|10|Y MRPS18 Mitochondrial Ribosomal Protein, Small subunit 217.0 0 0 0 0 -0.92194944026037 P42847 52.92622234611042 55.00000000000001 1.0 no 11097 chrXIV_58360r 29060 essential YNL306W 208 - GTACTTAACTACTTCCTCTT K|75|N silent|AAG>AAA|K|75 MRPS18 Mitochondrial Ribosomal Protein, Small subunit 217.0 0 0 0 0 0.5276242494533891 P42847 0.23987194895744324 45.6457884670823 35.0 1.0 no 11098 chrXIV_58510r 29063 essential YNL306W 358 - TAGCGAAATCTTCACTTTCT silent|TCG>TCC|S|125 silent|TCG>TCA|S|125 MRPS18 Mitochondrial Ribosomal Protein, Small subunit 217.0 0 0 0 0 0.888242927026234 P42847 42.74915604531553 35.0 1.0 no 11099 chrXIV_58527 29064 essential YNL306W 372 + TCGCTATCTACAGGTTGTTT L|126|V silent|CTA>TTA|L|126 S|125|W S|125|L MRPS18 Mitochondrial Ribosomal Protein, Small subunit 217.0 0 0 0 0 -0.25666670832373306 P42847 0.5063416361808777 0.02531183697283268 0.20048759877681727 48.901999076282216 40.0 1.0 no 11100 chrXIV_58534 29065 essential YNL306W 379 + CTACAGGTTGTTTAGGGTTT T|128|R T|128|I MRPS18 Mitochondrial Ribosomal Protein, Small subunit 217.0 0 0 0 0 0.4814593005174632 P42847 0.026009220629930496 0.01700688526034355 48.2135388633107 40.0 1.0 no 11101 chrXIV_58528 29066 essential YNL306W 373 + CGCTATCTACAGGTTGTTTA L|126|V silent|CTA>TTA|L|126 S|127|C S|127|F MRPS18 Mitochondrial Ribosomal Protein, Small subunit 217.0 0 0 0 0 -0.2861338750306286 P42847 0.5063416361808777 0.007519667968153954 0.0039889789186418065 47.21541459181242 40.0 1.0 no 11102 chrXIV_72917r 29068 high_effect YNL297C 3644 + TGCGATGACAGATGAATTTG A|1216|G A|1216|V MON2 MONensin sensitivity 1636.0 0 0 0 0 0.7500003263972369 P48563 0.9484469890594482 0.9504740238189696 0.3843802809715271 0.29481932520866394 40.038169713366706 40.0 0.0 no 11103 chrXIV_72938 29069 high_effect YNL297C 3626 - CATCGTATTTCGATATTAAT D|1215|H D|1215|N MON2 MONensin sensitivity 1636.0 0 0 0 0 -0.4149503882050464 P48563 0.9486550092697144 0.956179976463318 0.2147095799446106 0.8817699551582336 36.71695347994978 25.0 0.0 no 11104 chrXIV_73038 29070 high_effect YNL297C 3526 - ACTGTACGTAATATTGTAGT S|1182|T S|1182|N silent|ACG>ACC|T|1180 silent|ACG>ACA|T|1180 MON2 MONensin sensitivity 1636.0 0 0 0 0 -0.7419417375769495 P48563 0.9512869715690612 0.9536849856376648 0.5446376800537109 0.7538187503814697 39.70072775884052 30.0 0.0 no 11105 chrXIV_73075 29071 high_effect YNL297C 3489 - CACTTTTTCAATATATCTGA K|1169|N silent|AAG>AAA|K|1169 MON2 MONensin sensitivity 1636.0 0 0 0 0 0.5422891151181131 P48563 0.9355990290641784 0.21288546919822693 37.451686006212405 25.0 0.0 no 11106 chrXIV_73215r 29072 high_effect YNL297C 3346 + ACACTACCTGCGCCAAGGAA T|1117|S T|1117|I N|1116|K silent|AAC>AAT|N|1116 MON2 MONensin sensitivity 1636.0 0 0 0 0 -1.2523788025480609 P48563 0.9491789937019348 0.9472420215606691 0.9439849853515624 0.9997109174728394 0.1409616619348526 0.37328672409057617 52.300553321208156 55.00000000000001 0.0 no 11107 chrXIV_73220r 29073 high_effect YNL297C 3341 + AAACAACACTACCTGCGCCA N|1115|K silent|AAC>AAT|N|1115 N|1116|K silent|AAC>AAT|N|1116 MON2 MONensin sensitivity 1636.0 0 0 0 0 0.2575342846249194 P48563 0.9439849853515624 0.9439849853515624 0.8125191330909729 0.37328672409057617 49.035350712352574 50.0 0.0 no 11108 chrXIV_73250r 29074 high_effect YNL297C 3311 + GCTTTATCCGGAACACTTTA L|1105|V L|1105|F MON2 MONensin sensitivity 1636.0 0 0 0 0 -0.8889109055045985 P48563 0.9512209892272948 0.9587849974632264 0.043001066893339164 0.034383028745651245 46.711229948748205 40.0 0.0 no 11109 chrXIV_73311 29075 high_effect YNL297C 3253 - TTCATTTTCGAGTTCTTCAG E|1091|Q E|1091|K MON2 MONensin sensitivity 1636.0 0 0 0 0 -0.19259634605597886 P48563 0.956179976463318 0.9475290179252625 0.3409040570259094 0.475746363401413 44.2298834638097 35.0 0.0 no 11110 chrXIV_73323 29076 high_effect YNL297C 3241 - TTCTTCAGTGGACCATTCCT E|1087|Q E|1087|K E|1086|Q E|1086|K MON2 MONensin sensitivity 1636.0 0 0 0 0 0.11324677197373376 P48563 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.4278632998466492 0.1358719766139984 0.29420632123947144 0.2392052710056305 53.98823203927572 45.0 0.0 no 11111 chrXIV_73366 29077 high_effect YNL297C 3198 - TCTAAGAAAATTAGGTCCCA E|1073|Q E|1073|K MON2 MONensin sensitivity 1636.0 0 0 0 0 0.6281182766897468 P48563 0.956179976463318 0.9475290179252625 0.326824814081192 0.4270167052745819 41.51443840435553 35.0 0.0 no 11112 chrXIV_73524r 29078 high_effect YNL297C 3037 + CATCCAGTTCATCTCATGAT S|1014|C S|1014|F silent|TCC>TCG|S|1014 silent|TCC>TCT|S|1014 MON2 MONensin sensitivity 1636.0 0 0 0 0 0.06630638289287136 P48563 0.945252001285553 0.9294660091400146 0.01874927431344986 0.01731262542307377 48.297668347788935 40.0 0.0 no 11113 chrXIV_73606 29079 high_effect YNL297C 2958 - TCACTTAAATTTAATGTTTC S|992|T S|992|N D|993|H D|993|N MON2 MONensin sensitivity 1636.0 0 0 0 0 0.6040557992998691 P48563 0.9512869715690612 0.9536849856376648 0.9486550092697144 0.956179976463318 0.5811189413070679 0.4926182925701141 0.12485391646623613 0.5971857309341431 33.0094604516288 20.0 0.0 no 11114 chrXIV_73605 29080 high_effect YNL297C 2959 - ATCACTTAAATTTAATGTTT D|993|H D|993|N S|992|T S|992|N MON2 MONensin sensitivity 1636.0 0 0 0 0 -0.15317115043641508 P48563 0.9486550092697144 0.956179976463318 0.9512869715690612 0.9536849856376648 0.12485391646623613 0.5971857309341431 0.5811189413070679 0.4926182925701141 32.27541044535383 15.0 0.0 no 11115 chrXIV_73738 29081 high_effect YNL297C 2826 - ACGAATTTAATGACACTCAT V|949|L V|949|I MON2 MONensin sensitivity 1636.0 0 0 0 0 0.7687815732551033 P48563 0.9539830088615416 0.9574310183525084 0.0 0.0 37.154584578341606 30.0 0.0 no 11116 chrXIV_73662r 29082 high_effect YNL297C 2899 + TTTCTTCTATTAGTCAGTTC S|968|C S|968|F S|969|C S|969|F MON2 MONensin sensitivity 1636.0 0 0 0 0 0.2212109710113045 P48563 0.945252001285553 0.9294660091400146 0.945252001285553 0.9294660091400146 0.009627379477024078 0.0043064733035862455 0.0 0.0 43.290634138473756 30.0 0.0 no 11117 chrXIV_73894 29083 high_effect YNL297C 2670 - TCCTCAACTGTCCACTCGAA E|896|D silent|GAG>GAA|E|896 D|897|H D|897|N MON2 MONensin sensitivity 1636.0 0 0 0 0 0.0589974143791603 P48563 0.94931298494339 0.9486550092697144 0.956179976463318 0.616055965423584 0.035718832165002816 0.3499475121498108 51.446579233829034 50.0 0.0 no 11118 chrXIV_73895r 29085 high_effect YNL297C 2666 + ACCATTCGAGTGGACAGTTG P|890|R P|890|L P|890|A P|890|S MON2 MONensin sensitivity 1636.0 0 0 0 0 0.08124908959523494 P48563 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 49.31938232626834 50.0 0.0 no 11119 chrXIV_73860 29086 high_effect YNL297C 2704 - ATCATCTATATCCTCATTCA D|908|H D|908|N D|907|H D|907|N MON2 MONensin sensitivity 1636.0 0 0 0 0 0.7153095343655802 P48563 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.0 0.0 0.008262109011411667 0.02169990912079811 44.70702900370009 30.0 0.0 no 11120 chrXIV_73905r 29087 high_effect YNL297C 2656 + TCATTAATTCACCATTCGAG I|886|M silent|ATC>ATT|I|886 MON2 MONensin sensitivity 1636.0 0 0 0 0 0.2427122567338655 P48563 0.9598389863967896 0.008885733783245087 41.7077163210202 35.0 0.0 no 11121 chrXIV_74059r 29088 high_effect YNL297C 2502 + TCGATAAAACAGTTGGATAT S|835|W S|835|L MON2 MONensin sensitivity 1636.0 0 0 0 0 0.4419304440967323 P48563 0.9288619756698608 0.9298099875450134 0.014079329557716846 0.1907234936952591 35.84536062417396 30.0 0.0 no 11122 chrXIV_74256 29090 high_effect YNL297C 2308 - TATCAATTTGATCATATAGG L|775|F silent|TTG>TTA|L|775 MON2 MONensin sensitivity 1636.0 0 0 0 0 -0.9871925499880044 P48563 0.9587849974632264 0.09635184705257416 34.752298787969444 25.0 0.0 no 11123 chrXIV_74368 29091 high_effect YNL297C 2196 - AACGCCTTGTTGTAAATGCA silent|GCG>GCC|A|738 silent|GCG>GCA|A|738 A|738|P A|738|T MON2 MONensin sensitivity 1636.0 0 0 0 0 -0.08378251896949113 P48563 0.9573720097541808 0.9523990154266356 0.12443602830171585 0.6424611210823059 45.53260918983449 40.0 0.0 no 11124 chrXIV_74578 29092 high_effect YNL297C 1986 - ACGTCTGATTTAGTCAGTAT V|669|L V|669|I D|668|H D|668|N MON2 MONensin sensitivity 1636.0 0 0 0 0 0.7491401100544235 P48563 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 0.34220337867736816 1.0 0.016895389184355736 0.05463923141360283 44.286996595552644 35.0 0.0 no 11125 chrXIV_74581 29093 high_effect YNL297C 1983 - TCTGATTTAGTCAGTATTGG D|668|H D|668|N MON2 MONensin sensitivity 1636.0 0 0 0 0 0.6144186126973248 P48563 0.9486550092697144 0.956179976463318 0.016895389184355736 0.05463923141360283 42.57933707458011 35.0 0.0 no 11126 chrXIV_74770 29096 high_effect YNL297C 1794 - TGTCTTGAACTAATATTCCT R|604|T R|604|K MON2 MONensin sensitivity 1636.0 0 0 0 0 0.07920012565553143 P48563 0.932735025882721 0.955805003643036 0.02845925465226173 1.0 41.037639859720684 30.0 0.0 no 11127 chrXIV_74771 29097 high_effect YNL297C 1793 - GTCTTGAACTAATATTCCTG R|604|T R|604|K MON2 MONensin sensitivity 1636.0 0 0 0 0 0.3034741209934084 P48563 0.932735025882721 0.955805003643036 0.02845925465226173 1.0 41.037639859720684 35.0 0.0 no 11128 chrXIV_74813r 29098 high_effect YNL297C 1748 + TGCAGATTCTGCGCAAAATA A|584|G A|584|V MON2 MONensin sensitivity 1636.0 0 0 0 0 -0.12177484179199966 P48563 0.9484469890594482 0.9504740238189696 0.3737149238586426 0.2839926779270172 43.335226567599754 40.0 0.0 no 11129 chrXIV_75005r 29099 high_effect YNL297C 1556 + GTCACTAAAGGACAAATTAA S|520|* S|520|L L|521|V silent|CTA>TTA|L|521 MON2 MONensin sensitivity 1636.0 0 1 0 0 -0.6812800592383459 P48563 0.9298099875450134 0.9512209892272948 0.2006983906030655 0.5895848870277405 34.13432867607571 30.0 0.0 no 11130 chrXIV_75068r 29100 high_effect YNL297C 1493 + GACATCGATATTCCACTTGG T|499|R T|499|I S|500|W S|500|L MON2 MONensin sensitivity 1636.0 0 0 0 0 1.0005097155194944 P48563 0.9476869702339172 0.9472420215606691 0.9288619756698608 0.9298099875450134 0.041579093784093864 0.022450581192970283 0.048951391130685806 0.3920581638813019 46.32074042162924 45.0 0.0 no 11131 chrXIV_75205 29102 high_effect YNL297C 1359 - TCCTCAATTTTCTTCTCTAG E|459|D silent|GAG>GAA|E|459 D|460|H D|460|N MON2 MONensin sensitivity 1636.0 0 0 0 0 0.12228094233174695 P48563 0.94931298494339 0.9486550092697144 0.956179976463318 0.61903977394104 0.10916226357221603 0.5025853514671326 45.68131796220126 35.0 0.0 no 11132 chrXIV_75256r 29104 high_effect YNL297C 1305 + ATCTGTAACCACTTATGCGA I|436|M silent|ATC>ATT|I|436 MON2 MONensin sensitivity 1636.0 0 0 0 0 -0.07466472850335626 P48563 0.9598389863967896 0.028059832751750943 46.06850383691494 40.0 0.0 no 11133 chrXIV_75257r 29105 high_effect YNL297C 1304 + CATCTGTAACCACTTATGCG I|436|M silent|ATC>ATT|I|436 MON2 MONensin sensitivity 1636.0 0 0 0 0 0.12356218084669475 P48563 0.9598389863967896 0.028059832751750943 46.15136549465251 45.0 0.0 no 11134 chrXIV_75335r 29106 high_effect YNL297C 1226 + AACAAAGTTTATGCATTTAT T|410|R T|410|I MON2 MONensin sensitivity 1636.0 0 0 0 0 0.4845610991710772 P48563 0.9476869702339172 0.9472420215606691 0.2649391293525696 0.3136861324310303 34.307158194414846 20.0 0.0 no 11135 chrXIV_75560r 29109 high_effect YNL297C 1001 + ACTATCTCTAGAACTTTTCA L|335|V silent|CTA>TTA|L|335 S|336|C S|336|F MON2 MONensin sensitivity 1636.0 0 0 0 0 0.4564779210640518 P48563 0.9512209892272948 0.945252001285553 0.9294660091400146 0.04141494631767273 0.005437865853309631 0.002895846497267485 40.88968999550178 30.0 0.0 no 11136 chrXIV_75585 29110 high_effect YNL297C 979 - TCTTTGCCATCCACTTAAAT R|333|T R|333|K W|331|C W|331|* MON2 MONensin sensitivity 1636.0 0 0 0 0 0.4140513083572929 P48563 0.932735025882721 0.955805003643036 0.8858469724655151 0.022428523749113083 1.0 0.0 46.34143065957738 35.0 0.0 no 11137 chrXIV_75595r 29111 high_effect YNL297C 966 + TCTGTCGAATCCAATTTAAG S|323|C S|323|F silent|GTC>GTG|V|324 silent|GTC>GTT|V|324 MON2 MONensin sensitivity 1636.0 0 0 0 0 0.2746596246414353 P48563 0.945252001285553 0.9294660091400146 0.005437865853309631 0.002895846497267485 39.83574518984205 35.0 0.0 no 11138 chrXIV_75622r 29112 high_effect YNL297C 939 + ATCTTGTCGCTGTTAATCCA I|314|M silent|ATC>ATT|I|314 MON2 MONensin sensitivity 1636.0 0 0 0 0 0.9478866526387428 P48563 0.9598389863967896 0.16316621005535126 49.401885878289356 40.0 0.0 no 11139 chrXIV_75705 29113 high_effect YNL297C 859 - ACGACAACTCCTTACAGCGG R|293|P R|293|H C|292|S C|292|Y MON2 MONensin sensitivity 1636.0 0 0 0 0 -0.6072323478507384 P48563 0.9099509716033936 0.9570810198783876 0.9421560168266296 0.9290120005607604 0.0 0.0 0.3144420981407165 1.0 49.61385777353185 55.00000000000001 0.0 no 11140 chrXIV_75702 29114 high_effect YNL297C 862 - ACAACGACAACTCCTTACAG C|294|S C|294|Y R|293|P R|293|H MON2 MONensin sensitivity 1636.0 0 0 0 0 -0.8645204039570821 P48563 0.9421560168266296 0.9290120005607604 0.9099509716033936 0.9570810198783876 0.21277685463428495 0.007463009562343359 0.0 0.0 43.15913741708641 45.0 0.0 no 11141 chrXIV_75851 29117 high_effect YNL297C 713 - TTTCCAGGCCATAGTCTATT E|244|Q E|244|K silent|CTG>CTC|L|243 silent|CTG>CTA|L|243 MON2 MONensin sensitivity 1636.0 0 0 0 0 -0.3634615214426568 P48563 0.956179976463318 0.9475290179252625 0.0 0.0 52.053476139436206 40.0 0.0 no 11142 chrXIV_76032 29119 high_effect YNL297C 532 - ATCATCCACTACAGATTCAA D|184|H D|184|N D|183|H D|183|N MON2 MONensin sensitivity 1636.0 0 0 0 0 0.7273655294287161 P48563 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.04080387204885483 0.15848076343536374 0.09921476244926453 0.6250290870666504 43.43198760216927 35.0 0.0 no 11143 chrXIV_76074 29120 high_effect YNL297C 490 - ATCGATAAGCTGCTGTAAAG D|170|H D|170|N MON2 MONensin sensitivity 1636.0 0 0 0 0 0.06342714120990245 P48563 0.9486550092697144 0.956179976463318 0.015116240829229357 0.2110656052827835 40.73092924518164 40.0 0.0 no 11144 chrXIV_76098 29121 high_effect YNL297C 466 - ACTCGCAGTACCAACTACTA silent|GCG>GCC|A|161 silent|GCG>GCA|A|161 S|162|T S|162|N MON2 MONensin sensitivity 1636.0 0 0 0 0 1.2898225623889925 P48563 0.9512869715690612 0.9536849856376648 0.06249069795012474 0.18648897111415866 48.11842966536091 45.0 0.0 no 11145 chrXIV_76099 29122 high_effect YNL297C 465 - CTCGCAGTACCAACTACTAC silent|GCG>GCC|A|161 silent|GCG>GCA|A|161 A|161|P A|161|T MON2 MONensin sensitivity 1636.0 0 0 0 0 1.2546848663272832 P48563 0.9573720097541808 0.9523990154266356 0.0 0.0 48.11842966536091 50.0 0.0 no 11146 chrXIV_76111 29123 high_effect YNL297C 453 - ACTACTACGGGTGCCTTATT V|158|L V|158|I V|157|L V|157|I MON2 MONensin sensitivity 1636.0 0 0 0 0 -0.0278733160277415 P48563 0.9539830088615416 0.9574310183525084 0.9539830088615416 0.9574310183525084 0.3871491849422455 0.5984801650047302 0.04504610225558281 0.22511987388134005 50.85094861619415 45.0 0.0 no 11147 chrXIV_76124r 29124 high_effect YNL297C 437 + TCTGCTGCATGTACCTAATA L|147|V silent|CTG>TTG|L|147 L|148|V silent|CTG>TTG|L|148 MON2 MONensin sensitivity 1636.0 0 0 0 0 -0.5752559194698557 P48563 0.9512209892272948 0.9512209892272948 0.08239038288593292 0.056308865547180176 47.9152853851283 40.0 0.0 no 11148 chrXIV_76280 29128 high_effect YNL297C 284 - CATCCAAAATTTCAGACAGC D|101|H D|101|N L|100|F silent|TTG>TTA|L|100 MON2 MONensin sensitivity 1636.0 0 0 0 0 0.6181894371392868 P48563 0.9486550092697144 0.956179976463318 0.9587849974632264 0.006946926470845939 0.02117850817739964 0.0 41.81082616922794 40.0 0.0 no 11149 chrXIV_76388r 29135 high_effect YNL297C 173 + TTTCGCACTCCCTTTCGTGT F|59|L silent|TTC>TTT|F|59 A|60|G A|60|V MON2 MONensin sensitivity 1636.0 0 0 0 0 -0.10083668984290547 P48563 0.9387490153312684 0.9484469890594482 0.9504740238189696 0.0 0.005194613244384527 1.0 57.38029418658318 50.0 0.0 no 11150 chrXIV_76443 29137 high_effect YNL297C 121 - TACTCTTTTCAATATCTCAA V|47|L V|47|I R|46|T R|46|K MON2 MONensin sensitivity 1636.0 0 0 0 0 -0.2182596725132492 P48563 0.9539830088615416 0.9574310183525084 0.932735025882721 0.955805003643036 0.07889793813228607 0.2910666763782501 1.0 0.10510997474193573 38.16402993558364 25.0 0.0 no 11151 chrXIV_76533 29138 high_effect YNL297C 31 - TGCTTCAAGTTGCCTTTGCA A|17|P A|17|T E|16|Q E|16|K MON2 MONensin sensitivity 1636.0 0 0 0 0 0.5502961263664621 P48563 0.9573720097541808 0.9523990154266356 0.956179976463318 0.9475290179252625 0.06403926014900208 1.0 0.6022590398788452 0.8904032111167908 53.59157981845532 45.0 0.0 no 11152 chrXIV_86241 29139 essential YNL290W 23 + GAGCAAAGAAAACCTTCCAT S|9|R silent|AGC>AGT|S|9 RFC3 Replication Factor C 340.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.12942015002347634 P38629 0.9417110085487366 0.5215056538581848 41.94473895053368 40.0 1.0 no 11153 chrXIV_86279r 29142 essential YNL290W 64 - GTACACTTCGTCCAACGTTT silent|GTG>GTC|V|27 silent|GTG>GTA|V|27 V|27|L V|27|M RFC3 Replication Factor C 340.0 0 0 0 0 0.5265067485722884 P38629 0.9539830088615416 0.9587630033493042 1.0 0.0958361104130745 -0.8064000010490417 0.2143999934196472 -1.4067800045013428 -1.1291799545288086 49.440131658133105 45.0 1.0 no 11154 chrXIV_86321r 29143 essential YNL290W 106 - ATCTACAAATTTACGAACTG D|42|H D|42|N V|41|L V|41|I RFC3 Replication Factor C 340.0 0 0 0 0 -0.11780272279241928 P38629 0.9486550092697144 0.956179976463318 0.9539830088615416 0.9574310183525084 0.05710459128022194 1.0 0.0948711708188057 1.0 -0.9082000255584716 -0.8532000184059143 -0.23420000076293945 0.11060000211000444 -1.949779987335205 -0.6472399830818176 34.732729888942515 30.0 1.0 no 11155 chrXIV_86326 29144 essential YNL290W 108 + GTTCGTAAATTTGTAGATGA R|38|G R|38|C RFC3 Replication Factor C 340.0 0 0 0 0 0.12092794139964255 P38629 0.8994590044021606 0.8926740288734436 0.3671196699142456 0.05152613297104836 2.746400117874145 1.9673999547958372 38.106725355512474 30.0 1.0 no 11156 chrXIV_86353 29145 essential YNL290W 135 + TTGCCACATCTTCTATTCTA P|47|A P|47|S P|47|R P|47|L RFC3 Replication Factor C 340.0 0 0 0 0 -0.33200445180880644 P38629 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.0 0.0 0.0 0.0 2.9019999504089355 2.5027999877929688 2.5585999488830566 2.428800106048584 2.8145999908447266 2.04040002822876 3.696199893951416 1.2691999673843384 48.025321896789244 35.0 1.0 no 11157 chrXIV_86387r 29148 essential YNL290W 172 - AACAATTGTAGAAGTTTTAC V|64|L V|64|I RFC3 Replication Factor C 340.0 0 0 0 0 -0.28165678606367056 P38629 0.9539830088615416 0.9574310183525084 1.0 0.028443707153201107 -1.0764000415802002 -0.9531999826431274 -0.9100800156593324 -0.8817399740219116 -1.1449999809265137 -0.9800000190734864 33.264219096498216 25.0 1.0 no 11158 chrXIV_86471r 29150 essential YNL290W 256 - CACATCAATACCTCTGTCAT V|92|L V|92|M D|91|H D|91|N RFC3 Replication Factor C 340.0 0 0 0 0 -0.4231326163351648 P38629 0.9539830088615416 0.9587630033493042 0.9486550092697144 0.956179976463318 0.02231912687420845 0.004637054633349179 0.04243772849440575 0.21812525391578674 0.01119999960064888 -0.8659999966621399 0.11479999870061874 0.28839999437332153 -0.7097399830818176 -1.881659984588623 46.239444826243236 40.0 1.0 no 11159 chrXIV_86585r 29152 essential YNL290W 370 - CAACGCATTTTGTGCGGCAT silent|GCG>GCC|A|129 silent|GCG>GCA|A|129 A|129|P A|129|T RFC3 Replication Factor C 340.0 0 0 0 0 -0.34219290941688224 P38629 0.9573720097541808 0.9523990154266356 0.0 0.0 2.7894001007080083 -0.2632000148296356 3.2505800724029537 -0.050599999725818634 4.0949296951293945 1.82315993309021 50.680983583529844 50.0 1.0 no 11160 chrXIV_86591r 29153 essential YNL290W 376 - TCTTCTCAACGCATTTTGTG R|132|T R|132|K R|131|T R|131|K RFC3 Replication Factor C 340.0 0 0 0 0 1.0568632670390623 P38629 0.932735025882721 0.955805003643036 0.932735025882721 0.955805003643036 0.009159808978438377 0.02317025139927864 0.0 0.0 -0.4546000063419342 0.0024000001139938827 0.02759999968111515 0.5368000268936157 1.6032600402832031 1.1385999917984009 1.108309984207153 0.6863200068473816 45.814273220394 40.0 1.0 no 11161 chrXIV_86630r 29154 essential YNL290W 415 - TACACAGAACCGCGTATTCT V|145|L V|145|I C|144|S C|144|Y RFC3 Replication Factor C 340.0 0 0 0 0 -0.06864685950075028 P38629 0.9539830088615416 0.9574310183525084 0.9421560168266296 0.9290120005607604 0.8114840984344482 1.0 0.009923642501235008 0.0008424802217632532 -1.3645999431610107 -0.3174000084400177 2.3410000801086426 4.0064001083374015 47.18407500337771 45.0 1.0 no 11162 chrXIV_86675 29155 essential YNL290W 457 + TTACACCTGCGTTATTGAGT T|154|R T|154|I P|155|A P|155|S RFC3 Replication Factor C 340.0 0 0 0 0 -0.2907271573988547 P38629 0.9476869702339172 0.9472420215606691 0.9562489986419678 0.9498909711837769 0.004966598004102707 1.0 0.0 0.0 0.9437999725341796 0.008000000379979609 1.764799952507019 2.2609999179840092 0.7331200242042542 0.0808199942111969 2.299280166625977 2.892735004425049 47.966039254021894 40.0 1.0 no 11163 chrXIV_86621 29156 essential YNL290W 403 + AACGGTACACCAAGAATACG R|136|G R|136|W RFC3 Replication Factor C 340.0 0 0 0 0 -0.08791913672304807 P38629 0.8994590044021606 0.9448130130767822 0.005320836789906025 0.0010972429299727082 0.210999995470047 0.7142000198364258 1.152790069580078 0.8677600026130676 41.016582675101354 45.0 1.0 no 11164 chrXIV_86680r 29157 essential YNL290W 465 - GTGCACCTACTCAATAACGC C|161|S C|161|Y R|160|S silent|AGG>AGA|R|160 RFC3 Replication Factor C 340.0 0 0 0 0 -0.3679391079515609 P38629 0.9421560168266296 0.9290120005607604 0.9087679982185364 0.0 0.0 0.0 0.9539999961853028 5.165999889373778 1.4470200538635254 1.6119600534439087 0.6315999627113342 10.71660041809082 48.34218997777953 50.0 1.0 no 11165 chrXIV_86720r 29159 essential YNL290W 505 - CTCAATGGCCTCTTGGGGCA E|175|Q E|175|K RFC3 Replication Factor C 340.0 0 0 0 0 0.02655985406262296 P38629 0.956179976463318 0.9475290179252625 0.5892254710197449 0.9219167232513428 -0.5630000233650208 -0.6890000104904175 58.73842166037458 60.0 1.0 no 11166 chrXIV_86803 29164 essential YNL290W 585 + GCCTTAATAGAACTTTCTAA silent|GCC>GCG|A|196 silent|GCC>GCT|A|196 A|196|G A|196|V RFC3 Replication Factor C 340.0 0 0 0 0 0.0809602329659102 P38629 0.9484469890594482 0.9504740238189696 0.015607393346726894 0.0048000700771808616 1.6100000143051147 2.619800090789795 1.7267999649047852 0.21267999708652496 39.6083374975496 30.0 1.0 no 11167 chrXIV_86804 29165 essential YNL290W 586 + CCTTAATAGAACTTTCTAAT silent|GCC>GCG|A|196 silent|GCC>GCT|A|196 RFC3 Replication Factor C 340.0 0 0 0 0 -0.10590200995943604 P38629 36.18362674818161 25.0 1.0 no 11168 chrXIV_86804r 29166 essential YNL290W 589 - CCCATTAGAAAGTTCTATTA G|203|R G|203|R G|203|A G|203|E RFC3 Replication Factor C 340.0 0 0 0 0 0.9656112916564624 P38629 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.0 0.0 0.0 0.0 6.092400074005128 6.092400074005128 4.302999973297118 6.56879997253418 41.039617528713 30.0 1.0 no 11169 chrXIV_86868 29167 essential YNL290W 650 + TACTTTAGACAATCCCGACG T|218|S T|218|I RFC3 Replication Factor C 340.0 0 0 0 0 0.8009740646282779 P38629 0.9491789937019348 0.9472420215606691 0.4109153747558594 0.007691986858844756 0.1501999944448471 1.4678000211715698 0.5888000130653381 1.5456000566482544 45.141781147602046 45.0 1.0 no 11170 chrXIV_86881r 29168 essential YNL290W 666 - TCACTGATCTCATCCTCGTC S|228|T S|228|N D|229|H D|229|N RFC3 Replication Factor C 340.0 0 0 0 0 -0.109271933860152 P38629 0.9512869715690612 0.9536849856376648 0.9486550092697144 0.956179976463318 1.0 0.15366116166114807 0.08291836827993393 0.3317288160324097 1.108199954032898 -0.0584000013768673 1.0915999412536619 0.4334000051021576 0.4431999921798706 -0.1202000007033348 52.94285657876873 50.0 1.0 no 11171 chrXIV_86882r 29169 essential YNL290W 667 - GTCACTGATCTCATCCTCGT D|229|H D|229|N S|228|T S|228|N RFC3 Replication Factor C 340.0 0 0 0 0 0.9271610676601522 P38629 0.9486550092697144 0.956179976463318 0.9512869715690612 0.9536849856376648 0.08291836827993393 0.3317288160324097 1.0 0.15366116166114807 1.0915999412536619 0.4334000051021576 1.108199954032898 -0.0584000013768673 0.4431999921798706 -0.1202000007033348 54.59899659464554 50.0 1.0 no 11172 chrXIV_86905 29170 essential YNL290W 687 + GACGTTATCTATGAATGCTG D|230|E silent|GAC>GAT|D|230 RFC3 Replication Factor C 340.0 0 0 0 0 0.7145114100139429 P38629 0.9532920122146606 1.0 -0.852400004863739 41.78660903940755 40.0 1.0 no 11173 chrXIV_92058r 29176 essential YNL287W 67 - GTTCATACAATCCTGATAAA M|28|I M|28|I SEC21 SECretory 935.0 0 0 0 0 -5.444956960653565 P32074 0.9553959965705872 0.9553959965705872 38.51362133131147 30.0 1.0 yes 11174 chrXIV_92106r 29178 essential YNL287W 115 - AATCAATAAACGACATCTCT L|44|F silent|TTG>TTA|L|44 SEC21 SECretory 935.0 0 0 0 0 0.14120730994328765 P32074 0.9587849974632264 0.010850553400814531 35.97085420460513 30.0 1.0 no 11175 chrXIV_92128 29179 essential YNL287W 134 + TTCTCGCTTGCTGAGACTCT S|46|C S|46|F R|47|G R|47|C SEC21 SECretory 935.0 0 0 0 0 -0.8804185640204008 P32074 0.945252001285553 0.9294660091400146 0.8994590044021606 0.8926740288734436 0.015810813754796982 0.01553397346287966 0.009942836128175259 0.0014721831539645789 -0.07400000095367433 4.4608001708984375 53.698313562105 50.0 1.0 no 11176 chrXIV_92135 29180 essential YNL287W 141 + TTGCTGAGACTCTTGGCCCA L|49|V silent|CTG>TTG|L|49 SEC21 SECretory 935.0 0 0 0 0 0.20214877959173194 P32074 0.9512209892272948 0.9088367223739624 1.044800043106079 57.93069675601669 55.00000000000001 1.0 no 11177 chrXIV_92167r 29182 essential YNL287W 176 - ATGCAGTTGCTTCATTCTGT A|65|P A|65|T SEC21 SECretory 935.0 0 0 0 0 0.2486635446531835 P32074 0.9573720097541808 0.9523990154266356 0.20199820399284366 0.7186837196350098 51.235384698283504 40.0 1.0 no 11178 chrXIV_92217 29184 essential YNL287W 223 + AACACCAGAACGATCCTTTA H|76|D H|76|Y H|76|Q silent|CAC>CAT|H|76 SEC21 SECretory 935.0 0 0 0 0 -0.4228426235033792 P32074 0.9473130106925964 0.9489949941635132 0.9588389992713928 0.16934135556221008 0.01938033476471901 0.033744435757398605 44.33886627013339 40.0 1.0 no 11179 chrXIV_92242 29187 essential YNL287W 248 + GGCTGTTTATTTGGCAATCA A|84|G A|84|V SEC21 SECretory 935.0 0 0 0 0 -0.5643363763589659 P32074 0.9484469890594482 0.9504740238189696 0.008994708769023418 0.08353955298662186 1.8350000381469729 3.0583999156951904 48.326055456336356 40.0 1.0 no 11180 chrXIV_92296 29188 essential YNL287W 302 + GGCAACCTCTTCAATCATGA A|102|G A|102|V T|103|S T|103|I SEC21 SECretory 935.0 0 0 0 0 -0.05742026144207535 P32074 0.9484469890594482 0.9504740238189696 0.9491789937019348 0.9472420215606691 0.0039032984059304 1.0 0.0 0.0 48.42707008470188 45.0 1.0 no 11181 chrXIV_92301r 29189 essential YNL287W 310 - AACGTCCTTCATGATTGAAG V|110|L V|110|I D|109|H D|109|N SEC21 SECretory 935.0 0 0 0 0 0.7423885835093266 P32074 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 0.2725323438644409 0.7506287097930908 0.0 0.0 42.42025127038835 40.0 1.0 no 11182 chrXIV_92309 29190 essential YNL287W 315 + ATCATGAAGGACGTTCAAAA I|106|M silent|ATC>ATT|I|106 SEC21 SECretory 935.0 0 0 0 0 -0.3670286047230541 P32074 0.9598389863967896 0.0061564608477056035 37.69466532880245 35.0 1.0 no 11183 chrXIV_92388 29193 essential YNL287W 394 + CTACTGCTTTTTCCGCTGAA T|133|S T|133|I A|134|G A|134|V SEC21 SECretory 935.0 0 0 0 0 0.7658745240440532 P32074 0.9491789937019348 0.9472420215606691 0.9484469890594482 0.9504740238189696 0.1961890012025833 0.3468579947948456 0.003102847374975681 1.0 50.28700664886514 45.0 1.0 no 11184 chrXIV_92400r 29194 essential YNL287W 409 - ACTTTTTAATAACCTTTCAG S|143|T S|143|N SEC21 SECretory 935.0 0 0 0 0 0.14738150436566896 P32074 0.9512869715690612 0.9536849856376648 1.0 0.3888734877109528 37.5174697287311 25.0 1.0 no 11185 chrXIV_92487r 29195 essential YNL287W 496 - TCTGATAGTGACTTCTGAAA R|172|T R|172|K SEC21 SECretory 935.0 0 0 0 0 0.2883340605657627 P32074 0.932735025882721 0.955805003643036 0.019802629947662357 1.0 39.883617970901696 35.0 1.0 no 11186 chrXIV_92517r 29196 essential YNL287W 526 - AACAGCTTCTTGAGTTTCAT V|182|L V|182|I A|181|P A|181|T SEC21 SECretory 935.0 0 0 0 0 -0.2465792132348125 P32074 0.9539830088615416 0.9574310183525084 0.9573720097541808 0.9523990154266356 0.2321351170539856 0.6413167715072632 0.012669901363551615 0.08287784457206726 44.94333256246454 35.0 1.0 no 11187 chrXIV_92558r 29197 essential YNL287W 567 - TCGCTATTACCGTGTTGATT S|195|T S|195|N E|196|Q E|196|K SEC21 SECretory 935.0 0 0 0 0 -0.6525485992740708 P32074 0.9512869715690612 0.9536849856376648 0.956179976463318 0.9475290179252625 0.4132296741008759 0.32690662145614624 0.7888503074645996 0.7125244140625 48.24835414994402 40.0 1.0 no 11188 chrXIV_92604 29198 essential YNL287W 610 + TTTCTCAATATCATGCTCTT S|205|C S|205|F Q|206|E Q|206|* SEC21 SECretory 935.0 0 0 0 0 0.08820936301741378 P32074 0.945252001285553 0.9294660091400146 0.9590039849281312 0.09652043879032136 0.3689311444759369 0.022556103765964508 43.530875071193684 30.0 1.0 no 11189 chrXIV_92638 29199 essential YNL287W 644 + ACTGAAGAAAACTGATAAAA L|216|V silent|CTG>TTG|L|216 SEC21 SECretory 935.0 0 0 0 0 -0.311504321756828 P32074 0.9512209892272948 0.05301174148917198 28.852005592362612 25.0 1.0 no 11190 chrXIV_92718r 29201 essential YNL287W 727 - AATCTTGACCAATTCTACCT K|248|N silent|AAG>AAA|K|248 SEC21 SECretory 935.0 0 1 0 0 -1.3024408637043037 P32074 0.9355990290641784 0.004946541041135788 1.204800009727478 44.660588030334395 35.0 1.0 no 11191 chrXIV_92766 29202 essential YNL287W 772 + CTCAATTATTTAGTCAATTC Q|259|E Q|259|* SEC21 SECretory 935.0 0 0 0 0 0.44493796074246456 P32074 0.9590039849281312 0.3350191116333008 35.80502391674685 25.0 1.0 no 11192 chrXIV_92784 29203 essential YNL287W 790 + TCAGGCCACTTTTGTCTGAT F|264|L silent|TTC>TTT|F|264 P|266|A P|266|S SEC21 SECretory 935.0 0 0 0 0 0.4243383358322788 P32074 0.9387490153312684 0.9562489986419678 0.9498909711837769 0.901174783706665 0.5673583745956421 0.469927579164505 52.78505916978071 45.0 1.0 no 11193 chrXIV_92866 29204 essential YNL287W 872 + TACTCGCAATTCCCGCTTAG T|292|S T|292|I R|293|G R|293|C SEC21 SECretory 935.0 0 0 0 0 0.4698131870064536 P32074 0.9491789937019348 0.9472420215606691 0.8994590044021606 0.8926740288734436 1.0 0.10227278620004654 0.31655892729759216 0.1623731553554535 51.4727350410875 50.0 1.0 no 11194 chrXIV_92877r 29205 essential YNL287W 886 - TAACTCGGGAGCCACTAAGC E|301|D silent|GAG>GAA|E|301 E|301|Q E|301|K SEC21 SECretory 935.0 0 0 0 0 -0.385279742143079 P32074 0.94931298494339 0.956179976463318 0.9475290179252625 0.6152024269104004 0.5730903148651123 0.9047038555145264 50.134334344969204 55.00000000000001 1.0 no 11195 chrXIV_92974 29207 essential YNL287W 980 + AATCTTAAATAGAATATCCA I|328|M silent|ATC>ATT|I|328 SEC21 SECretory 935.0 0 0 0 0 0.06282382747492911 P32074 0.9598389863967896 0.09131375700235367 32.824359684445824 20.0 1.0 no 11196 chrXIV_93002r 29209 essential YNL287W 1011 - TTACAAACAACAATCTTTTC C|343|S C|343|Y SEC21 SECretory 935.0 0 0 0 0 1.0040279618883654 P32074 0.9421560168266296 0.9290120005607604 0.004583964589983225 0.0018937094137072565 33.418049857751555 25.0 1.0 no 11197 chrXIV_93192r 29210 essential YNL287W 1201 - GTTCAAAGACAACGTACGAA L|406|F silent|TTG>TTA|L|406 SEC21 SECretory 935.0 0 0 0 0 1.0569451813540929 P32074 0.9587849974632264 0.009327096864581108 38.526668838682326 40.0 1.0 no 11198 chrXIV_93447r 29212 essential YNL287W 1456 - AACATATAATGATGGATTTG V|492|L V|492|I SEC21 SECretory 935.0 0 0 0 0 0.06076962434512456 P32074 0.9539830088615416 0.9574310183525084 0.019173445180058483 1.0 32.875465874399765 25.0 1.0 no 11199 chrXIV_93567r 29213 essential YNL287W 1576 - ACTTATGATTGACTCATATA S|532|T S|532|N SEC21 SECretory 935.0 0 0 0 0 -1.6662281913894934 P32074 0.9512869715690612 0.9536849856376648 0.10289633274078368 0.010439873673021792 37.18503666155237 25.0 1.0 no 11200 chrXIV_93805 29215 essential YNL287W 1811 + TCAAGTTCGTAAGTTTACTG Q|605|E Q|605|* SEC21 SECretory 935.0 0 0 0 0 0.3907808596996459 P32074 0.9590039849281312 0.6770285964012146 40.216682168571204 35.0 1.0 no 11201 chrXIV_93892 29217 essential YNL287W 1898 + CACTTTGGATACTACACCAG T|634|S T|634|I SEC21 SECretory 935.0 0 1 0 0 -0.06744787413610151 P32074 0.9491789937019348 0.9472420215606691 0.7001439332962036 0.17943868041038513 45.494469678875866 45.0 1.0 no 11202 chrXIV_93908r 29219 essential YNL287W 1917 - TCTGGAACACTCTCTGCCTC E|646|Q E|646|K SEC21 SECretory 935.0 0 1 0 0 -1.1147810630694273 P32074 0.956179976463318 0.9475290179252625 0.5714517831802368 0.8782972097396851 54.44014209555042 55.00000000000001 1.0 no 11203 chrXIV_93877 29220 essential YNL287W 1883 + TCAAAAGTCTGAAACCACTT Q|629|E Q|629|* SEC21 SECretory 935.0 0 1 0 0 0.7091672548258757 P32074 0.9590039849281312 1.0 39.09817489463978 35.0 1.0 no 11204 chrXIV_93976r 29223 essential YNL287W 1985 - TAGCTAGTAGATCTTCTTGG A|668|P A|668|T SEC21 SECretory 935.0 0 0 0 0 -0.8031485977427496 P32074 0.9573720097541808 0.9523990154266356 0.28183531761169434 0.600717306137085 45.57620520789226 40.0 1.0 no 11205 chrXIV_94047 29225 essential YNL287W 2053 + GTCAATTAGTAAATAGTTCT Q|686|E Q|686|* SEC21 SECretory 935.0 0 0 0 0 0.2620924996770021 P32074 0.9590039849281312 0.5140923261642456 35.93047202798203 25.0 1.0 no 11206 chrXIV_94048 29226 essential YNL287W 2054 + TCAATTAGTAAATAGTTCTA Q|686|E Q|686|* SEC21 SECretory 935.0 0 0 0 0 0.2679497080084613 P32074 0.9590039849281312 0.5140923261642456 32.97778184406462 20.0 1.0 no 11207 chrXIV_107796 29227 essential YNL282W 109 + TGCATGATCAGCCATTGATT H|38|D H|38|Y POP3 Processing Of Precursor RNAs 195.0 0 0 0 0 0.41435803330530907 P53833 0.9473130106925964 0.9489949941635132 0.587580680847168 0.03790809214115143 48.261591642747824 40.0 1.0 no 11208 chrXIV_107807r 29228 essential YNL282W 123 - TGCAGCAGCTGCCAAATCAA silent|CTG>CTC|L|47 silent|CTG>CTA|L|47 silent|CTG>CTC|L|46 silent|CTG>CTA|L|46 POP3 Processing Of Precursor RNAs 195.0 0 0 0 0 -1.2138726322734812 P53833 50.924706893108294 50.0 1.0 no 11209 chrXIV_107863 29231 essential YNL282W 176 + ATCGAAGGAGAACTACCCTT S|60|W S|60|L POP3 Processing Of Precursor RNAs 195.0 0 0 0 0 -0.394507522421004 P53833 0.9288619756698608 0.9298099875450134 0.011648074723780157 0.13200044631958008 46.329695938162324 45.0 1.0 no 11210 chrXIV_107878r 29232 essential YNL282W 194 - AATCTGTATACAGCTCCCAA D|71|H D|71|N POP3 Processing Of Precursor RNAs 195.0 0 0 0 0 0.17289906267629912 P53833 0.9486550092697144 0.956179976463318 0.0790906623005867 0.4948835670948029 47.60183524236516 40.0 1.0 no 11211 chrXIV_107948r 29234 essential YNL282W 264 - TTGCACACAAATAGACATAC C|94|S C|94|Y silent|GTG>GTC|V|93 silent|GTG>GTA|V|93 POP3 Processing Of Precursor RNAs 195.0 0 0 0 0 0.2690063628465577 P53833 0.9421560168266296 0.9290120005607604 0.0 0.0 37.65558080766772 35.0 1.0 no 11212 chrXIV_108007 29235 essential YNL282W 320 + AATCCCGCTATTATGCTATA I|108|M silent|ATC>ATT|I|108 P|109|A P|109|S POP3 Processing Of Precursor RNAs 195.0 0 0 0 0 0.307995549566868 P53833 0.9598389863967896 0.9562489986419678 0.9498909711837769 0.0134507454931736 0.0 0.0 46.46162133045107 35.0 1.0 no 11213 chrXIV_108011r 29236 essential YNL282W 327 - GGCGCCATATAGCATAATAG silent|GCG>GCC|A|115 silent|GCG>GCA|A|115 A|115|P A|115|T POP3 Processing Of Precursor RNAs 195.0 0 0 0 0 -0.7901301091710833 P53833 0.9573720097541808 0.9523990154266356 0.026090363040566444 0.05566549301147461 46.54842790021678 45.0 1.0 no 11214 chrXIV_108032r 29239 essential YNL282W 348 - TGCACCAGTTTAACCGTCAT silent|GTG>GTC|V|122 silent|GTG>GTA|V|122 V|122|L V|122|M POP3 Processing Of Precursor RNAs 195.0 0 0 0 0 0.9201239701481138 P53833 0.9539830088615416 0.9587630033493042 0.032705340534448624 0.006596355699002743 50.910703337474224 45.0 1.0 no 11215 chrXIV_108033r 29241 essential YNL282W 349 - CTGCACCAGTTTAACCGTCA silent|GTG>GTC|V|122 silent|GTG>GTA|V|122 V|122|L V|122|M POP3 Processing Of Precursor RNAs 195.0 0 0 0 0 0.2683986994796241 P53833 0.9539830088615416 0.9587630033493042 0.032705340534448624 0.006596355699002743 52.67067317562054 50.0 1.0 no 11216 chrXIV_108080 29242 essential YNL282W 393 + TTCAAGTCGGTTTCTAAATA F|132|L silent|TTC>TTT|F|132 POP3 Processing Of Precursor RNAs 195.0 0 0 0 0 0.16464007775599154 P53833 0.9387490153312684 1.0 39.20101797924633 30.0 1.0 no 11217 chrXIV_109474 29245 high_effect YNL280C 918 - TTCACCCATCCCAATTCCAC silent|GTG>GTC|V|312 silent|GTG>GTA|V|312 V|312|L V|312|M ERG24 ERGosterol biosynthesis 438.0 0 0 0 0 0.6583530125615474 P32462 0.9539830088615416 0.9587630033493042 0.8943090438842773 0.2542846202850342 55.72223402598185 50.0 0.0 no 11218 chrXIV_109490r 29247 high_effect YNL280C 899 + TTACTTGAGTGTTTCCCCTG Y|301|* silent|TAC>TAT|Y|301 ERG24 ERGosterol biosynthesis 438.0 0 0 0 0 -0.5245844978720409 P32462 52.841675971289256 45.0 0.0 no 11219 chrXIV_109648r 29250 high_effect YNL280C 741 + GTCTTGGTTAATTTCTTGCA silent|GTC>GTG|V|248 silent|GTC>GTT|V|248 ERG24 ERGosterol biosynthesis 438.0 0 0 0 0 1.2401380920886498 P32462 46.593416960140296 35.0 0.0 no 11220 chrXIV_109690r 29251 high_effect YNL280C 699 + CATCACCATTACCTGAAGAC H|235|D H|235|Y H|235|Q silent|CAC>CAT|H|235 ERG24 ERGosterol biosynthesis 438.0 0 0 0 0 -0.2895390177035518 P32462 0.9473130106925964 0.9489949941635132 0.9588389992713928 0.07589393109083176 0.0502966046333313 0.3499442934989929 45.60072754452853 45.0 0.0 no 11221 chrXIV_109778 29252 high_effect YNL280C 614 - TATCTAATGGGCCGAGACGA D|211|H D|211|N ERG24 ERGosterol biosynthesis 438.0 0 0 0 0 0.5759835262943758 P32462 0.9486550092697144 0.956179976463318 0.0 0.0 47.97304075891993 50.0 0.0 no 11222 chrXIV_109813r 29253 high_effect YNL280C 576 + ATCATTTACGATTGGTTTAT I|193|M silent|ATC>ATT|I|193 ERG24 ERGosterol biosynthesis 438.0 0 0 0 0 1.5233781997096472 P32462 0.9598389863967896 0.2338958978652954 39.49487993627787 25.0 0.0 no 11223 chrXIV_109885 29254 high_effect YNL280C 507 - CCATTTTTCTTGAAGATCAA G|176|R G|176|S ERG24 ERGosterol biosynthesis 438.0 0 0 0 0 0.2428731275234267 P32462 0.941340982913971 0.951104998588562 40.31721061176978 30.0 0.0 no 11224 chrXIV_109987 29255 high_effect YNL280C 405 - TCATACAGATATTGCAATTC E|142|Q E|142|K silent|CTG>CTC|L|140 silent|CTG>CTA|L|140 ERG24 ERGosterol biosynthesis 438.0 0 0 0 0 0.4828945186714345 P32462 0.956179976463318 0.9475290179252625 0.2712191641330719 0.220497265458107 38.302956678033006 30.0 0.0 no 11225 chrXIV_110017r 29256 high_effect YNL280C 372 + ATCAGATGGAAATTGACTGA I|125|M silent|ATC>ATT|I|125 ERG24 ERGosterol biosynthesis 438.0 0 0 0 0 0.475220365427725 P32462 0.9598389863967896 0.1012170910835266 38.49367550784035 35.0 0.0 no 11226 chrXIV_110042r 29258 high_effect YNL280C 347 + TACAACTTTGGTCTTAGTTT T|117|R T|117|I T|118|S T|118|I ERG24 ERGosterol biosynthesis 438.0 0 0 0 0 0.8286283989083391 P32462 0.9476869702339172 0.9472420215606691 0.9491789937019348 0.9472420215606691 0.316609799861908 0.6267761588096619 0.17814019322395325 0.5139361023902893 42.08701244170351 30.0 0.0 no 11227 chrXIV_110077r 29259 high_effect YNL280C 312 + AAGCTTTCGTATAAGATCAA L|106|V L|106|F ERG24 ERGosterol biosynthesis 438.0 0 0 0 0 0.3288037977590745 P32462 0.9512209892272948 0.9587849974632264 0.05008765682578087 0.039305429905653 38.123145953212145 30.0 0.0 no 11228 chrXIV_110109r 29261 high_effect YNL280C 280 + TCATGAAGGGTGTTCAGTTA silent|GTC>GTG|V|94 silent|GTC>GTT|V|94 ERG24 ERGosterol biosynthesis 438.0 0 0 0 0 -0.371551476973576 P32462 46.06368461928167 40.0 0.0 no 11229 chrXIV_110159 29263 high_effect YNL280C 233 - CTGCCAGTATTCCATACCAC A|84|P A|84|T silent|CTG>CTC|L|83 silent|CTG>CTA|L|83 ERG24 ERGosterol biosynthesis 438.0 0 0 0 0 0.8656397186664911 P32462 0.9573720097541808 0.9523990154266356 0.09664991497993468 0.3283088505268097 53.68769930941284 50.0 0.0 no 11230 chrXIV_110170r 29265 high_effect YNL280C 219 + ACTGTCTATTGCCTGTGGTA T|74|S T|74|I silent|GTC>GTG|V|75 silent|GTC>GTT|V|75 ERG24 ERGosterol biosynthesis 438.0 0 0 0 0 1.179419966587174 P32462 0.9491789937019348 0.9472420215606691 0.5352720022201538 0.4257008731365204 53.334176318341925 45.0 0.0 no 11231 chrXIV_110193r 29266 high_effect YNL280C 196 + ATCTGGGCAATCGTGAATTA L|67|V silent|CTG>TTG|L|67 ERG24 ERGosterol biosynthesis 438.0 0 0 0 0 0.7193297361510451 P32462 0.9512209892272948 0.4837876558303833 44.38273601265831 40.0 0.0 no 11232 chrXIV_110206 29267 high_effect YNL280C 186 - TTGCCCAGATAGTAGCGCAA G|68|A G|68|D G|68|R G|68|S ERG24 ERGosterol biosynthesis 438.0 0 0 0 0 0.8663676154834565 P32462 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.5217027068138123 0.21084871888160706 0.3801119029521942 0.4112389087677002 52.93408004193861 50.0 0.0 no 11233 chrXIV_110209r 29268 high_effect YNL280C 180 + AAGCCATTGCGCTACTATCT P|62|A P|62|S P|62|R P|62|L ERG24 ERGosterol biosynthesis 438.0 0 0 0 0 0.5983226060164014 P32462 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.8073683381080627 0.6665560007095337 0.4706579744815826 0.2723334729671478 50.94947976172711 45.0 0.0 no 11234 chrXIV_110246 29269 high_effect YNL280C 146 - GCTCAACTATATCGAAATTC E|55|Q E|55|K E|55|D silent|GAG>GAA|E|55 ERG24 ERGosterol biosynthesis 438.0 0 0 0 0 -0.3227340337765067 P32462 0.956179976463318 0.9475290179252625 0.94931298494339 0.6020134687423706 0.9222227334976196 0.6282044649124146 38.55259059986662 35.0 0.0 no 11235 chrXIV_110275r 29270 high_effect YNL280C 114 + AGGCCCGATTATTTTATTAA P|40|A P|40|S P|40|R P|40|L ERG24 ERGosterol biosynthesis 438.0 0 0 0 0 -1.0025098401189951 P32462 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.679618239402771 0.6865912079811096 0.455727219581604 0.26361870765686035 43.63694045553751 30.0 0.0 no 11236 chrXIV_110331 29272 high_effect YNL280C 61 - CAGCCCTATGCTGATGCCTA silent|GGG>GGC|G|26 silent|GGG>GGA|G|26 G|26|A G|26|E ERG24 ERGosterol biosynthesis 438.0 0 0 0 0 0.62248041093401 P32462 0.9499930143356324 0.9438679814338684 0.5479782819747925 0.2860588133335113 58.26466181464963 55.00000000000001 0.0 no 11237 chrXIV_127500r 29276 essential YNL272C 1562 + TGCTATATCGGTTCGCTTGC A|522|G A|522|V 0 1 0 0 1.1257134706644192 P17065 0.9484469890594482 0.9504740238189696 0.4068952202796936 0.28810521960258484 52.607565914362176 50.0 0.0 no 11238 chrXIV_127601r 29278 essential YNL272C 1461 + ATACTTCATTGGACTCATAT L|489|V L|489|F H|490|D H|490|Y 0 0 0 0 0.054322701229697096 P17065 0.9512209892272948 0.9587849974632264 0.9473130106925964 0.9489949941635132 0.0 0.0 0.027797119691967964 0.009000459685921669 41.248646798731045 30.0 0.0 no 11239 chrXIV_127648 29279 essential YNL272C 1417 - CCATGCTCTTTGAATATTAG W|479|S W|479|* A|478|P A|478|T 0 0 0 0 -0.9805792683530185 P17065 0.8858469724655151 0.9573720097541808 0.9523990154266356 0.0 0.020811345428228382 0.021836835891008374 42.08356484853869 35.0 0.0 no 11240 chrXIV_127754r 29282 essential YNL272C 1308 + AAACGTTTAAGTTTTATGGC R|438|G R|438|C 0 0 0 0 0.02973224128526392 P17065 0.8994590044021606 0.8926740288734436 0.0 0.0 37.95417122271982 30.0 0.0 no 11241 chrXIV_127902r 29284 essential YNL272C 1160 + TGCTTTCCTGAGATCATTGA A|388|G A|388|V F|389|L silent|TTC>TTT|F|389 0 0 0 0 -0.003900852936085275 P17065 0.9484469890594482 0.9504740238189696 0.9387490153312684 0.0 0.0 0.0 48.20302561805618 40.0 0.0 no 11242 chrXIV_127951 29286 essential YNL272C 1114 - TAGCAAACACCAATGACACA L|377|F silent|TTG>TTA|L|377 0 0 0 0 0.23374861843882616 P17065 0.9587849974632264 0.02271228469908237 41.54387911623195 40.0 0.0 no 11243 chrXIV_128000r 29289 essential YNL272C 1062 + ACGTTGCACAAGACTGACGA T|355|R T|355|M H|357|D H|357|Y 0 0 0 0 -0.6116707070900801 P17065 0.9476869702339172 0.9502379894256592 0.9473130106925964 0.9489949941635132 0.0 0.0 0.532031238079071 0.1428946554660797 46.36746453112335 50.0 0.0 no 11244 chrXIV_128059 29291 essential YNL272C 1006 - ATCTCTAGATTCTCCACAAA D|342|H D|342|N R|341|T R|341|K 0 0 0 0 0.3811872869325966 P17065 0.9486550092697144 0.956179976463318 0.932735025882721 0.955805003643036 0.04888514801859856 0.9843152761459352 0.0 0.0 43.4509176650841 35.0 0.0 no 11245 chrXIV_128072r 29292 essential YNL272C 990 + CACGCCGCATGTTCCTTTTG H|331|Q silent|CAC>CAT|H|331 A|332|G A|332|V 0 0 0 0 0.17125046587268866 P17065 0.9588389992713928 0.9484469890594482 0.9504740238189696 0.3718811869621277 0.14023540914058685 0.0845409482717514 55.34516542591956 55.00000000000001 0.0 no 11246 chrXIV_128144 29296 essential YNL272C 921 - TTCGAAGTGGCTTGCTTTGC silent|TCG>TCC|S|313 silent|TCG>TCA|S|313 0 0 0 0 -0.3676302428206864 P17065 51.85196560429267 50.0 0.0 no 11247 chrXIV_128169 29298 essential YNL272C 896 - TACTTGAGTTGTAGCCAATT S|305|T S|305|N 0 0 0 0 -0.12145359405609972 P17065 0.9512869715690612 0.9536849856376648 0.09263894706964493 0.08116424083709718 44.82680035246358 35.0 0.0 no 11248 chrXIV_128234r 29299 essential YNL272C 828 + CTACTTTCCTTGATTATAGA L|278|V L|278|F 0 0 0 0 0.678069160254611 P17065 0.9512209892272948 0.9587849974632264 0.2908912599086761 0.06172465905547143 41.732913778959066 30.0 0.0 no 11249 chrXIV_128288 29302 essential YNL272C 777 - GCATTATCAATCTTAAGTAT A|266|P A|266|T 0 0 0 0 0.08209985557343469 P17065 0.9573720097541808 0.9523990154266356 0.01830917596817017 0.018125107511878014 37.544211054426974 25.0 0.0 no 11250 chrXIV_128292 29303 essential YNL272C 773 - TATCAATCTTAAGTATAGGC D|264|H D|264|N 0 0 0 0 0.3250363726645784 P17065 0.9486550092697144 0.956179976463318 0.0057129841297864905 0.01683682762086391 37.7816820407686 30.0 0.0 no 11251 chrXIV_128332 29305 essential YNL272C 733 - TCTTCGTATTAACTTTGATT R|251|T R|251|K R|250|P R|250|Q 0 0 0 0 0.5813922725769767 P17065 0.932735025882721 0.955805003643036 0.9099509716033936 0.949662983417511 0.0 0.0 0.008634350262582302 0.025196781381964684 38.864539689390604 25.0 0.0 no 11252 chrXIV_128363 29306 essential YNL272C 702 - GCCTTTATGTTTTCACAACG K|240|N silent|AAG>AAA|K|240 A|241|P A|241|T 0 0 0 0 -0.3922238917328961 P17065 0.9355990290641784 0.9573720097541808 0.9523990154266356 0.0163628738373518 0.17665423452854154 0.3026743531227112 45.97180938407684 40.0 0.0 no 11253 chrXIV_128468r 29308 essential YNL272C 594 + GCTTCCCAAGATATTTATAG A|199|G A|199|V S|200|C S|200|F 0 1 0 0 -0.3324702844536551 P17065 0.9484469890594482 0.9504740238189696 0.945252001285553 0.9294660091400146 0.40020015835762013 0.3217398226261139 0.0166158527135849 0.0126888332888484 43.611251163312495 35.0 0.0 no 11254 chrXIV_128539 29309 essential YNL272C 526 - TGCTGAATCACTCAATATTG A|182|P A|182|T 0 1 0 0 0.6060579331387025 P17065 0.9573720097541808 0.9523990154266356 0.3015038371086121 0.6096104383468628 39.52703991095626 35.0 0.0 no 11255 chrXIV_128620 29310 essential YNL272C 445 - TTTCAGATTCTTGAGCTGTA silent|CTG>CTC|L|154 silent|CTG>CTA|L|154 0 0 0 0 0.9997156296641172 P17065 45.40993429403983 35.0 0.0 no 11256 chrXIV_128935 29314 essential YNL272C 130 - TTCAATTGCTGCCTTCTGGC E|50|Q E|50|K 0 0 0 0 -1.4253322887941486 P17065 0.956179976463318 0.9475290179252625 0.6532817482948303 0.6669078469276428 54.620238090432174 50.0 0.0 no 11257 chrXIV_129015 29316 essential YNL272C 50 - TCTCGATCAATTGCGTAGAC E|23|Q E|23|K E|23|D silent|GAG>GAA|E|23 0 0 0 0 -0.07407552840763917 P17065 0.956179976463318 0.9475290179252625 0.94931298494339 0.0 0.0 0.0 45.03770970215533 45.0 0.0 no 11258 chrXIV_129016 29317 essential YNL272C 49 - CTCGATCAATTGCGTAGACA E|23|Q E|23|K L|21|F silent|TTG>TTA|L|21 0 0 0 0 0.0581907315915749 P17065 0.956179976463318 0.9475290179252625 0.9587849974632264 0.0 0.0 0.0 0.047219999134540565 45.33524289267109 45.0 0.0 no 11259 chrXIV_140970 29318 essential YNL267W 92 + ATTCACCCTTCACAATTGTG F|32|L silent|TTC>TTT|F|32 T|33|S T|33|I PIK1 Phosphatidyl Inositol Kinase 1066.0 0 0 0 0 0.3917080014582843 P39104 0.9387490153312684 0.9491789937019348 0.9472420215606691 0.3237603306770325 1.0 0.0938568115234375 47.2485811104616 40.0 1.0 no 11260 chrXIV_140975r 29319 essential YNL267W 100 - TAACTCCACACAATTGTGAA E|39|D silent|GAG>GAA|E|39 E|39|Q E|39|K PIK1 Phosphatidyl Inositol Kinase 1066.0 0 0 0 0 -0.05772757390165593 P39104 0.94931298494339 0.956179976463318 0.9475290179252625 0.6433261632919312 0.5179047584533691 0.8065462112426758 40.321195599792645 35.0 1.0 no 11261 chrXIV_141001 29320 essential YNL267W 123 + TGCAAACACTCCGAAAATAT C|42|W silent|TGC>TGT|C|42 H|44|D H|44|Y PIK1 Phosphatidyl Inositol Kinase 1066.0 0 0 0 0 0.02041718676278332 P39104 0.9286419749259948 0.9473130106925964 0.9489949941635132 0.02475594542920589 0.18695007264614105 1.0 38.37247323153657 35.0 1.0 no 11262 chrXIV_141198 29326 essential YNL267W 320 + GCAGTTACAAGCGTTACTAA Q|108|E Q|108|* PIK1 Phosphatidyl Inositol Kinase 1066.0 0 0 0 0 -1.5170690779491809 P39104 0.9590039849281312 0.2739821970462799 44.09519300093945 40.0 1.0 no 11263 chrXIV_141289 29331 essential YNL267W 411 + AATCTCTTTAACACAAGTTC L|139|V L|139|F silent|CTC>CTG|L|139 silent|CTC>CTT|L|139 PIK1 Phosphatidyl Inositol Kinase 1066.0 0 0 0 0 1.2324360217972972 P39104 0.9512209892272948 0.9587849974632264 0.023506540805101398 0.022250713780522343 0.22193999588489527 0.2357400059700012 37.493881379564755 30.0 1.0 no 11264 chrXIV_141360 29332 essential YNL267W 482 + TCTTTCCTCTATGATAATGT L|162|V L|162|F S|163|C S|163|F PIK1 Phosphatidyl Inositol Kinase 1066.0 0 0 0 0 0.09806757741595287 P39104 0.9512209892272948 0.9587849974632264 0.945252001285553 0.9294660091400146 0.04686400294303894 0.03551772609353065 0.1942962855100632 0.5322718024253845 0.43220001459121693 0.08972000330686569 -0.14190000295639038 -1.2883199453353882 0.7206000089645386 0.28720000386238104 -0.5550000071525574 -3.2890000343322754 43.023457086797116 30.0 1.0 no 11265 chrXIV_141415 29334 essential YNL267W 537 + AAACCATTAGTGGAATCTCA P|181|A P|181|S P|181|R P|181|L PIK1 Phosphatidyl Inositol Kinase 1066.0 0 0 0 0 -0.4563612455880572 P39104 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.04635031521320343 0.046043451875448234 0.13973940908908844 0.0309999231249094 41.370985231750005 35.0 1.0 no 11266 chrXIV_141418r 29335 essential YNL267W 543 - CTACCTTGAGATTCCACTAA G|187|A G|187|D G|187|R G|187|S PIK1 Phosphatidyl Inositol Kinase 1066.0 0 0 0 0 0.5415130468444963 P39104 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.24516896903514865 0.008876740001142025 0.006216525565832853 0.040968935936689384 45.89021284612295 40.0 1.0 no 11267 chrXIV_141545r 29336 essential YNL267W 670 - GCGATTTGAGCTAACTCTTT R|230|P R|230|H PIK1 Phosphatidyl Inositol Kinase 1066.0 0 1 0 0 0.4601208636815044 P39104 0.9099509716033936 0.9570810198783876 0.2740229070186615 0.1275257170200348 46.07935826372892 40.0 1.0 no 11268 chrXIV_141604r 29337 essential YNL267W 729 - GCATCTTCTTTAGTTTTTAT A|250|P A|250|T D|249|H D|249|N PIK1 Phosphatidyl Inositol Kinase 1066.0 0 0 0 0 0.8560587392945409 P39104 0.9573720097541808 0.9523990154266356 0.9486550092697144 0.956179976463318 0.28610676527023315 0.5964118838310242 0.05358714610338211 0.2104312926530838 42.93375001806572 25.0 1.0 no 11269 chrXIV_141629r 29338 essential YNL267W 754 - ACTATGTCTGGATTTCCTGA S|258|T S|258|N PIK1 Phosphatidyl Inositol Kinase 1066.0 0 0 0 0 -0.37128848901738826 P39104 0.9512869715690612 0.9536849856376648 0.3903350234031677 0.2357233911752701 48.392967790084754 40.0 1.0 no 11270 chrXIV_141766 29339 essential YNL267W 888 + TACGTTCATAGGACATATGA Y|297|* silent|TAC>TAT|Y|297 H|299|D H|299|Y PIK1 Phosphatidyl Inositol Kinase 1066.0 0 0 0 0 0.604279732507895 P39104 0.9473130106925964 0.9489949941635132 0.3003376424312592 0.07237929850816728 40.970988801433634 35.0 1.0 no 11271 chrXIV_141810 29341 essential YNL267W 932 + AAGCATTTCAAATACCGCAA S|312|R silent|AGC>AGT|S|312 PIK1 Phosphatidyl Inositol Kinase 1066.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.08762378374685359 P39104 0.9417110085487366 0.22077849507331848 41.32708406848269 35.0 1.0 no 11272 chrXIV_141983 29342 essential YNL267W 1105 + ATCTGCATAATATTCAACCA L|370|V silent|CTG>TTG|L|370 H|371|D H|371|Y PIK1 Phosphatidyl Inositol Kinase 1066.0 0 0 0 0 0.4253558526519596 P39104 0.9512209892272948 0.9473130106925964 0.9489949941635132 0.0 0.3550633192062378 0.31697288155555725 41.127557888758304 30.0 1.0 no 11273 chrXIV_142015 29343 essential YNL267W 1137 + GCTTCATCTGCTTCTTTAGA A|380|G A|380|V S|381|* S|381|L PIK1 Phosphatidyl Inositol Kinase 1066.0 0 1 0 0 0.6514896087226012 P39104 0.9484469890594482 0.9504740238189696 0.9298099875450134 0.3828165531158447 0.30586767196655273 0.21681945025920868 50.35702138228106 40.0 1.0 no 11274 chrXIV_142214 29346 essential YNL267W 1336 + CGCTAGAAACAATATCTCAA L|447|V silent|CTA>TTA|L|447 PIK1 Phosphatidyl Inositol Kinase 1066.0 0 0 0 0 0.14654698345432066 P39104 0.9512209892272948 0.0 37.561696565668846 35.0 1.0 no 11275 chrXIV_142249r 29347 essential YNL267W 1374 - GCACTCAATCTAGCTTCTGT S|464|T S|464|N A|465|P A|465|T PIK1 Phosphatidyl Inositol Kinase 1066.0 0 0 0 0 -0.4800500778629773 P39104 0.9512869715690612 0.9536849856376648 0.9573720097541808 0.9523990154266356 0.1838449388742447 0.01603712886571884 0.0452154353260994 0.2894698977470398 51.06222874703519 45.0 1.0 no 11276 chrXIV_142596 29349 essential YNL267W 1718 + TAGCAACAACACTCGATCTT S|574|R silent|AGC>AGT|S|574 N|575|K silent|AAC>AAT|N|575 PIK1 Phosphatidyl Inositol Kinase 1066.0 0 0 0 0 0.08417474516855443 P39104 0.9417110085487366 0.9439849853515624 0.5019111037254333 0.9701221585273744 43.001657967429935 40.0 1.0 no 11277 chrXIV_142653r 29352 essential YNL267W 1778 - TACTGGATAGACCTTCATTG S|599|T S|599|N PIK1 Phosphatidyl Inositol Kinase 1066.0 0 1 0 0 0.17357118463192175 P39104 0.9512869715690612 0.9536849856376648 0.7224714756011963 0.5761910080909729 44.171927426883876 40.0 1.0 no 11278 chrXIV_142697r 29354 essential YNL267W 1822 - TTCAGTCCTAACATGAGCTG E|614|Q E|614|K R|612|S silent|AGG>AGA|R|612 PIK1 Phosphatidyl Inositol Kinase 1066.0 0 1 0 0 1.0173558535377931 P39104 0.956179976463318 0.9475290179252625 0.9087679982185364 0.5093983411788939 0.7746802568435669 0.5983033180236816 47.51013678283754 45.0 1.0 no 11279 chrXIV_142837r 29356 essential YNL267W 1962 - CTTCTGTCTTGACTATCATC R|660|T R|660|K PIK1 Phosphatidyl Inositol Kinase 1066.0 0 0 0 0 0.022963864968901987 P39104 0.932735025882721 0.955805003643036 0.2812606692314148 0.8858885169029236 46.01416009042622 40.0 1.0 no 11280 chrXIV_142484r 29357 essential YNL267W 1609 - CTTCTTTAATAATCTTTCAT K|542|N silent|AAG>AAA|K|542 PIK1 Phosphatidyl Inositol Kinase 1066.0 0 0 0 0 0.2477211288716632 P39104 0.9355990290641784 0.5711333155632019 35.952551089826386 20.0 1.0 no 11281 chrXIV_142971 29360 essential YNL267W 2093 + AGCTGTTATGTTAGCACAAT A|699|G A|699|V PIK1 Phosphatidyl Inositol Kinase 1066.0 0 0 0 0 0.06493949188162129 P39104 0.9484469890594482 0.9504740238189696 0.05756427347660065 0.019222442060709 44.460247867482856 35.0 1.0 no 11282 chrXIV_143002r 29361 essential YNL267W 2127 - GTACTTTCTGATAACTGTTG S|715|T S|715|N PIK1 Phosphatidyl Inositol Kinase 1066.0 0 0 0 0 -0.23542147098691424 P39104 0.9512869715690612 0.9536849856376648 0.5191612243652344 0.10796892642974854 40.786132874334676 35.0 1.0 no 11283 chrXIV_143099r 29362 essential YNL267W 2224 - CTCACCTGCCATTCCATGAA E|748|Q E|748|K G|747|A G|747|D PIK1 Phosphatidyl Inositol Kinase 1066.0 0 0 0 0 -1.2761997204008142 P39104 0.956179976463318 0.9475290179252625 0.9499930143356324 0.9446240067481996 0.4316134452819824 0.029226135462522507 0.0 0.0 53.834834152396354 50.0 1.0 no 11284 chrXIV_143100r 29363 essential YNL267W 2225 - TCTCACCTGCCATTCCATGA E|748|Q E|748|K E|748|D silent|GAG>GAA|E|748 PIK1 Phosphatidyl Inositol Kinase 1066.0 0 0 0 0 0.5360901469754714 P39104 0.956179976463318 0.9475290179252625 0.94931298494339 0.4316134452819824 0.029226135462522507 0.06586211919784546 56.735865863345616 50.0 1.0 no 11285 chrXIV_143162 29364 essential YNL267W 2284 + CTTCATATCTAGGTGAAGAT S|763|* S|763|L PIK1 Phosphatidyl Inositol Kinase 1066.0 0 0 0 0 -1.9609242161798601 P39104 0.9298099875450134 41.06811285291525 35.0 1.0 no 11286 chrXIV_143163 29365 essential YNL267W 2285 + TTCATATCTAGGTGAAGATT S|763|* S|763|L PIK1 Phosphatidyl Inositol Kinase 1066.0 0 0 0 0 -1.2607808868262635 P39104 0.9298099875450134 39.424312133930705 30.0 1.0 no 11287 chrXIV_143261r 29367 essential YNL267W 2386 - TCTCAAATCATCACCCGTCT L|801|F silent|TTG>TTA|L|801 R|802|T R|802|K PIK1 Phosphatidyl Inositol Kinase 1066.0 0 0 0 0 -0.5505263712232928 P39104 0.9587849974632264 0.932735025882721 0.955805003643036 0.0 0.9740599989891052 0.8830528855323792 50.35977068065626 45.0 1.0 no 11288 chrXIV_147267r 29370 essential YNL263C 551 + CTACAAACTGTCTTCTACTC Y|185|* silent|TAC>TAT|Y|185 YIF1 YIP1-Interacting Factor 314.0 0 0 0 0 -0.29210222763462124 P53845 42.48662211676629 40.0 0.0 no 11289 chrXIV_147363r 29372 essential YNL263C 455 + AGACATGTACATGCCTATTA D|153|E silent|GAC>GAT|D|153 YIF1 YIP1-Interacting Factor 314.0 0 0 0 0 -0.27389843949606885 P53845 0.9532920122146606 0.0 44.433402164044935 35.0 0.0 no 11290 chrXIV_147628r 29375 essential YNL263C 190 + GTTCGATGGCATTCCAACTA S|65|W S|65|L YIF1 YIP1-Interacting Factor 314.0 0 0 0 0 0.31599773240246737 P53845 0.9288619756698608 0.9298099875450134 0.00394615950062871 0.025824064388871196 49.25463007894575 45.0 0.0 no 11291 chrXIV_147642r 29377 essential YNL263C 176 + CCAAGATCCTCGTGGTTCGA Q|60|E Q|60|* YIF1 YIP1-Interacting Factor 314.0 0 0 0 0 -0.05062601249762533 P53845 0.9590039849281312 0.05030938982963562 53.67640690084073 55.00000000000001 0.0 no 11292 chrXIV_147709 29380 essential YNL263C 112 - CGCATTACCTTGGCCATTCA A|44|P A|44|T YIF1 YIP1-Interacting Factor 314.0 0 0 0 0 0.0009436484757937014 P53845 0.9573720097541808 0.9523990154266356 0.3500310480594635 0.17611613869667053 54.7068204324803 50.0 0.0 no 11293 chrXIV_147710 29381 essential YNL263C 111 - GCATTACCTTGGCCATTCAC A|44|P A|44|T G|42|A G|42|D YIF1 YIP1-Interacting Factor 314.0 0 0 0 0 -0.2544138441326609 P53845 0.9573720097541808 0.9523990154266356 0.9499930143356324 0.9446240067481996 0.3500310480594635 0.17611613869667053 0.9342892169952391 0.7374419569969177 54.433211885872076 50.0 0.0 no 11294 chrXIV_147806 29386 essential YNL263C 15 - TCACTTGTTGCATATGCGTA S|11|T S|11|N E|12|Q E|12|K YIF1 YIP1-Interacting Factor 314.0 0 0 0 0 0.3766896489049414 P53845 0.9512869715690612 0.9536849856376648 0.956179976463318 0.9475290179252625 0.23188313841819766 0.07803395390510559 0.5828644633293152 0.9114187955856324 48.146631934643544 40.0 0.0 no 11295 chrXIV_148249r 29388 essential YNL262W 40 - GCCAGCTGAATATCTTGCAG G|20|R G|20|S G|20|A G|20|D 0 1 0 0 0.05418587883049508 P21951 0.5003232359886169 0.6902335286140442 0.668792188167572 0.4923972487449646 50.81296900902846 50.0 1.0 no 11296 chrXIV_148374 29389 essential YNL262W 162 + TACGTACCGCCGCAATACAA Y|55|* silent|TAC>TAT|Y|55 P|57|A P|57|S 0 0 0 0 -0.6731188198143456 P21951 48.91244314569048 50.0 1.0 no 11297 chrXIV_148383r 29390 essential YNL262W 174 - TCAAACCTGCCATTGTATTG D|65|H D|65|N R|63|S silent|AGG>AGA|R|63 0 0 0 0 0.07270170499572709 P21951 45.80146895652462 40.0 1.0 no 11298 chrXIV_148448 29394 essential YNL262W 236 + GACGAACATGCACGCAACGC T|80|R T|80|M N|81|K silent|AAC>AAT|N|81 0 0 0 0 0.8601941746863724 P21951 0.003948168829083443 0.012307074852287771 0.0 48.336190296475365 60.0 1.0 no 11299 chrXIV_148482 29396 essential YNL262W 270 + ACCTTATCCAGTGGTAGTAA silent|ACC>ACG|T|91 silent|ACC>ACT|T|91 T|91|S T|91|I 0 0 0 0 1.054822227791068 P21951 0.6945238709449768 0.1775750368833542 48.80113987812586 40.0 1.0 no 11300 chrXIV_148488 29398 essential YNL262W 276 + TCCAGTGGTAGTAATGGCGG silent|TCC>TCG|S|93 silent|TCC>TCT|S|93 S|93|C S|93|F 0 0 0 0 -0.8713495392765419 P21951 0.15602806210517886 0.10940559953451157 52.57147684449847 55.00000000000001 1.0 no 11301 chrXIV_148527 29399 essential YNL262W 315 + GAACGTGTAACGACCAACCA R|107|G R|107|C 0 0 0 0 0.48748487556569897 P21951 45.913629001571216 50.0 1.0 no 11302 chrXIV_148536 29400 essential YNL262W 324 + ACGACCAACCAAGGTATTTC T|109|R T|109|M T|110|S T|110|I 0 0 0 0 0.6204884894206046 P21951 46.0892680087768 45.0 1.0 no 11303 chrXIV_148570 29402 essential YNL262W 358 + ACTTTTTAGATGAAGAGGGT Y|120|* silent|TAC>TAT|Y|120 0 0 0 0 -1.9731953743696988 P21951 41.46521408977566 35.0 1.0 no 11304 chrXIV_148619r 29403 essential YNL262W 410 - TACACGCAATAAAGAAGTAT C|143|S C|143|Y silent|GCG>GCC|A|142 silent|GCG>GCA|A|142 0 0 0 0 -0.1931926582798585 P21951 0.1099325269460678 0.0030810288153588767 34.772109264868156 30.0 1.0 no 11305 chrXIV_148706 29405 essential YNL262W 494 + AAGCTTACAAATCATTAGAA S|166|R silent|AGC>AGT|S|166 0 0 0 0 0.8531820531835276 P21951 0.8292022347450256 34.0405200374463 25.0 1.0 no 11306 chrXIV_148738 29406 essential YNL262W 526 + CCATGGACAATCACCTTTTA silent|ACC>ACG|T|176 silent|ACC>ACT|T|176 0 0 0 0 -1.3522568703337343 P21951 46.73516763613981 40.0 1.0 no 11307 chrXIV_148738r 29407 essential YNL262W 529 - CCCTAAAAGGTGATTGTCCA G|183|R G|183|R G|183|A G|183|E 0 0 0 0 0.1033444894858722 P21951 0.004449449013918638 0.004449449013918638 0.045344434678554535 0.0064277672208845615 48.453424665643304 45.0 1.0 no 11308 chrXIV_148798r 29409 essential YNL262W 589 - CCTGGCCTCGAATAACTGAT R|203|T R|203|K A|202|P A|202|T 0 0 0 0 0.34168555329762984 P21951 0.006185472477227449 0.10492558032274246 0.013540896587073805 0.04539412632584572 49.39913301978021 50.0 1.0 no 11309 chrXIV_148810 29410 essential YNL262W 598 + TCGAGGCCAGGAAACTCCTG F|200|L silent|TTC>TTT|F|200 A|202|G A|202|V 0 0 0 0 0.009904104863135256 P21951 1.0 0.0019383096368983386 1.0 52.882159309055176 60.0 1.0 no 11310 chrXIV_148964r 29415 essential YNL262W 755 - TGTCCTTGTCTATAGATACT D|258|H D|258|N K|257|N silent|AAG>AAA|K|257 0 0 0 0 -0.1002231169883614 P21951 0.02611587196588516 0.704091489315033 0.5073145031929016 45.94605046002829 35.0 1.0 no 11311 chrXIV_149060r 29416 essential YNL262W 851 - TATCAAATGCCATTACCACA D|290|H D|290|N 0 0 0 0 -0.07756036329319221 P21951 0.0 0.0 43.84967471273046 35.0 1.0 no 11312 chrXIV_149119r 29418 essential YNL262W 910 - CATCATTATTTGATCTACGG M|309|I M|309|I 0 0 0 0 0.9927809063607036 P21951 0.15515103936195376 0.15515103936195376 40.64093772030094 35.0 1.0 no 11313 chrXIV_149122r 29419 essential YNL262W 913 - AATCATCATTATTTGATCTA M|310|I M|310|I M|309|I M|309|I 0 0 0 0 0.1682801444830439 P21951 0.0 0.0 0.15515103936195376 0.15515103936195376 35.788569268242554 20.0 1.0 no 11314 chrXIV_149254r 29423 essential YNL262W 1045 - TTCATCGTTTTCGTTAAATA E|355|Q E|355|K D|354|H D|354|N 0 0 0 0 -0.046428494040419314 P21951 0.0 0.0 0.009401871822774409 0.33232206106185913 38.34761311753157 25.0 1.0 no 11315 chrXIV_149325 29424 essential YNL262W 1113 + ACTGTTATATCCACCTTCAA T|372|S T|372|I 0 0 0 0 0.4987441292991691 P21951 0.09212065488100052 0.003144292626529932 46.43269875021758 35.0 1.0 no 11316 chrXIV_149338r 29425 essential YNL262W 1129 - ATCGAAAAAGTCACCATTGA D|383|H D|383|N 0 0 0 0 0.2426943330408021 P21951 0.0 0.0 39.10388395363293 35.0 1.0 no 11317 chrXIV_147739r 29427 essential YNL263C 79 + AACGACCAATGCAAATTCCG R|28|G R|28|* P|29|A P|29|S YIF1 YIP1-Interacting Factor 314.0 0 0 0 0 -0.5973646507603015 P53845 0.8994590044021606 0.9562489986419678 0.9498909711837769 0.33050981163978577 1.0 0.5475102663040161 43.185761251523616 45.0 0.0 no 11318 chrXIV_149464 29428 essential YNL262W 1252 + CTCACATGGATTGTTTCCGT H|419|D H|419|Y H|419|Q silent|CAC>CAT|H|419 0 0 0 0 -1.6821031581661172 P21951 0.0 0.0 0.0 50.6150686003486 45.0 1.0 no 11319 chrXIV_149465 29429 essential YNL262W 1253 + TCACATGGATTGTTTCCGTT H|419|Q silent|CAC>CAT|H|419 H|419|D H|419|Y 0 0 0 0 -2.7438608222180294 P21951 0.0 0.0 0.0 49.06261943259017 40.0 1.0 yes 11320 chrXIV_149532 29430 essential YNL262W 1320 + GCTGTTACTCAATCTAAGCT A|441|G A|441|V 0 0 0 0 -0.2749200968171772 P21951 0.0 0.0 46.282882443741705 40.0 1.0 no 11321 chrXIV_149702 29435 essential YNL262W 1490 + TACTATTATTCCTTTGAACC T|498|S T|498|I 0 0 0 0 -0.20195856145737626 P21951 0.4037619233131409 0.03061809949576855 41.551351819645326 30.0 1.0 no 11322 chrXIV_149721r 29437 essential YNL262W 1512 - CCCTTTCTCAATGTTTCATC K|510|N silent|AAG>AAA|K|510 G|511|R G|511|S 0 0 0 0 -0.6030070321836039 P21951 0.00508295651525259 0.0 0.0 49.290128544102856 40.0 1.0 no 11323 chrXIV_149746r 29439 essential YNL262W 1537 - CAACATTTCACACAAAGTAC M|518|I M|518|I 0 0 0 0 -0.0018616335354941784 P21951 0.3814328908920288 0.3814328908920288 36.94075322314171 35.0 1.0 no 11324 chrXIV_149823 29440 essential YNL262W 1611 + CCCATTGAGAGGTTCTATGA silent|CCC>CCG|P|538 silent|CCC>CCT|P|538 P|538|R P|538|L 0 0 0 0 -0.4523219293311106 P21951 0.1457926630973816 0.03369345888495445 49.730377979489106 45.0 1.0 no 11325 chrXIV_149950r 29443 essential YNL262W 1741 - TTCTTGTAATAATTCATCAA E|587|Q E|587|K 0 0 0 0 0.33008817721152506 P21951 0.17629285156726834 0.020740428939461708 34.329667106207644 20.0 1.0 no 11326 chrXIV_150016r 29444 essential YNL262W 1807 - ATTCGTTACTTTATCTACAC silent|ACG>ACC|T|608 silent|ACG>ACA|T|608 0 0 0 0 0.4449333082356831 P21951 40.48892898287863 30.0 1.0 no 11327 chrXIV_150111r 29445 essential YNL262W 1902 - ACATCTACATGATAGATCAA V|641|L V|641|I D|640|H D|640|N 0 0 0 0 -2.8263586342287144 P21951 0.0 0.0 0.0 0.0 37.69241903660236 30.0 1.0 yes 11328 chrXIV_150238r 29446 essential YNL262W 2029 - CCATTTTAACTTTCTTGCAC W|683|S W|683|* 0 0 0 0 0.5151674463341857 P21951 0.0 44.344659676165925 35.0 1.0 no 11329 chrXIV_150421 29447 essential YNL262W 2209 + AACGTTTAACTGAATATTCA R|738|G R|738|C 0 0 0 0 0.19225857370486304 P21951 0.0 0.0 35.017724269997466 25.0 1.0 no 11330 chrXIV_150513r 29448 essential YNL262W 2304 - TTCACGGTATCGACGTAGAA silent|GTG>GTC|V|774 silent|GTG>GTA|V|774 V|774|L V|774|M 0 0 0 0 0.24702901635152125 P21951 0.0 0.0 44.643878091504405 45.0 1.0 no 11331 chrXIV_150538r 29450 essential YNL262W 2329 - TTCGTAACGCCTATCACGAA E|783|Q E|783|K 0 0 0 0 0.4284799714494918 P21951 0.05980836972594261 0.04879942163825035 46.05939752895046 45.0 1.0 no 11332 chrXIV_150608r 29452 essential YNL262W 2399 - CTCTCGCATGCTTATCAGAT R|806|T R|806|K silent|GCG>GCC|A|805 silent|GCG>GCA|A|805 0 0 0 0 0.5545547950702089 P21951 0.2350767403841019 0.04272516444325447 49.88973476290629 45.0 1.0 no 11333 chrXIV_150609r 29453 essential YNL262W 2400 - TCTCTCGCATGCTTATCAGA R|806|T R|806|K D|807|H D|807|N 0 0 0 0 0.2187307575069676 P21951 0.2350767403841019 0.04272516444325447 0.0784825012087822 0.26001882553100586 51.04308979062858 45.0 1.0 no 11334 chrXIV_150775r 29455 essential YNL262W 2566 - TCTCGCCATTTGAATGATCG silent|GCG>GCC|A|861 silent|GCG>GCA|A|861 R|862|T R|862|K 0 0 0 0 0.6464367250560009 P21951 0.0060232882387936115 0.17705856263637546 46.51790170725571 45.0 1.0 no 11335 chrXIV_150822 29457 essential YNL262W 2610 + CCATTAGAATTAGATACTGA P|871|R P|871|L 0 0 0 0 -0.2678491679466906 P21951 0.0 0.0 37.898742585641116 30.0 1.0 no 11336 chrXIV_150980r 29460 essential YNL262W 2771 - TCAATGGGTCTTTTAATTCT L|930|F silent|TTG>TTA|L|930 0 0 0 0 1.1579157735563477 P21951 0.043749392032623284 41.793277895510016 30.0 1.0 no 11337 chrXIV_151056r 29462 essential YNL262W 2847 - GGCAAAATCATGGCCTTATA L|955|F silent|TTG>TTA|L|955 0 0 0 0 1.451677830538744 P21951 0.0 45.12960700596176 40.0 1.0 no 11338 chrXIV_151077r 29463 essential YNL262W 2868 - TTTCCTTCTTCCTTGGAACT G|962|A G|962|E G|962|R G|962|R 0 0 0 0 0.056669907643573166 P21951 0.04012460261583328 0.04557605087757111 0.018459336832165718 0.018459336832165718 51.09546477356172 40.0 1.0 no 11339 chrXIV_151267 29465 essential YNL262W 3055 + TAGCAAGCGTATGTAACCGT A|1020|G A|1020|V 0 0 0 0 0.10605172240012804 P21951 0.08167420327663423 0.006157238036394118 47.40278546989247 45.0 1.0 no 11340 chrXIV_151283r 29466 essential YNL262W 3074 - AATCAAGAACATCTAACCAA D|1031|H D|1031|N 0 0 0 0 0.2728548958684965 P21951 0.5440096259117126 0.3042908906936645 35.800578595273855 30.0 1.0 no 11341 chrXIV_151402 29467 essential YNL262W 3190 + CTACTTCTATTACGACGGCA T|1065|S T|1065|I S|1066|C S|1066|F 0 1 0 0 1.2321606878341278 P21951 0.0 0.0 0.005153668113052845 0.0020572927314788107 46.794655641873646 45.0 1.0 no 11342 chrXIV_151500r 29469 essential YNL262W 3291 - TCAGTAACAGGTGCATTGAA E|1104|Q E|1104|K 0 0 0 0 0.04335625924624117 P21951 0.01785785332322121 0.01384036522358656 43.66297831919729 40.0 1.0 no 11343 chrXIV_151533r 29470 essential YNL262W 3324 - TCCGCTGAAAATATTGCGAC silent|GCG>GCC|A|1114 silent|GCG>GCA|A|1114 D|1115|H D|1115|N 0 0 0 0 0.2944758694646729 P21951 0.003527284367009997 0.00719831231981516 43.7440021160387 45.0 1.0 no 11344 chrXIV_151561 29472 essential YNL262W 3349 + CCATCAAAAGGTCTTTTCTG silent|CCC>CCG|P|1117 silent|CCC>CCT|P|1117 I|1118|M silent|ATC>ATT|I|1118 0 0 0 0 0.6557717282530868 P21951 0.00642409548163414 43.49125731050759 40.0 1.0 no 11345 chrXIV_151619 29473 essential YNL262W 3407 + TATCAGAACCATAATCGATT I|1137|M silent|ATC>ATT|I|1137 0 0 0 0 0.5940108901991712 P21951 0.2162232846021652 38.38861617601992 30.0 1.0 no 11346 chrXIV_151620 29474 essential YNL262W 3408 + ATCAGAACCATAATCGATTG I|1137|M silent|ATC>ATT|I|1137 0 0 0 0 0.2072239663407126 P21951 0.2162232846021652 38.92728193338258 35.0 1.0 no 11347 chrXIV_151817 29476 essential YNL262W 3605 + GACAAAGAATGTACCAACAA T|1203|R T|1203|I 0 1 0 0 -0.6020795765639302 P21951 0.5191940665245056 0.1938907653093338 36.2762130151591 35.0 1.0 no 11348 chrXIV_151830r 29478 essential YNL262W 3621 - TCTTTTATCTTGCCCATTGT D|1214|H D|1214|N 0 0 0 0 -0.3269010388958965 P21951 0.06897790729999542 0.33301302790641785 50.983430298000364 35.0 1.0 no 11349 chrXIV_152002r 29484 essential YNL262W 3793 - CCCAACATAGTCCTCGTCCA G|1271|R G|1271|R G|1271|A G|1271|E 0 0 0 0 -0.2771692150143271 P21951 0.01824263110756874 0.01824263110756874 0.6854451298713684 0.032047342509031296 57.37303505144378 55.00000000000001 1.0 no 11350 chrXIV_152057r 29485 essential YNL262W 3848 - GACGCTTTCTATCTCTTGCT R|1289|P R|1289|H K|1288|N silent|AAG>AAA|K|1288 0 0 0 0 0.5983078908407204 P21951 0.013052417896687984 0.09436153620481492 0.4884895086288452 52.048433895010255 45.0 1.0 no 11351 chrXIV_152155 29487 essential YNL262W 3943 + AATCATATGCGAACTCCACT S|1316|* S|1316|L 0 0 0 0 -1.8723690090130147 P21951 0.8049084544181824 44.66401411848239 40.0 1.0 no 11352 chrXIV_152156 29488 essential YNL262W 3944 + ATCATATGCGAACTCCACTT S|1316|* S|1316|L 0 0 0 0 -0.9498200613154966 P21951 0.8049084544181824 46.36717417284643 40.0 1.0 no 11353 chrXIV_152181 29489 essential YNL262W 3969 + GTCTTACAATACAAGGATTC silent|GTC>GTG|V|1324 silent|GTC>GTT|V|1324 Q|1326|E Q|1326|* 0 0 0 0 0.5078158549158458 P21951 0.29702335596084595 38.99736885945129 35.0 1.0 no 11354 chrXIV_152370r 29495 essential YNL262W 4161 - CCTGCTGGATTAGACGTTTT G|1394|R G|1394|S A|1393|P A|1393|T 0 0 0 0 0.7989410229630607 P21951 49.86108388277751 45.0 1.0 no 11355 chrXIV_152414 29497 essential YNL262W 4202 + TCTACCGGAATCTGTCTTTC L|1402|V silent|CTA>TTA|L|1402 P|1403|A P|1403|S 0 0 0 0 0.4396431587540317 P21951 1.0 0.07632597535848618 0.3436879515647888 48.799181838755324 45.0 1.0 no 11356 chrXIV_152399 29498 essential YNL262W 4187 + GCTATTCAAAATTACTCTAC L|1397|V silent|CTA>TTA|L|1397 F|1398|L silent|TTC>TTT|F|1398 0 0 0 0 0.5761588811886821 P21951 0.011781626380980015 0.03629566356539726 36.93221216042753 30.0 1.0 no 11357 chrXIV_152463 29499 essential YNL262W 4251 + TTCAACGATGAAAATGTACT F|1418|L silent|TTC>TTT|F|1418 N|1419|K silent|AAC>AAT|N|1419 0 0 0 0 0.4772932725100338 P21951 0.9929146766662598 0.04264351725578308 35.0702682633443 30.0 1.0 no 11358 chrXIV_152508r 29500 essential YNL262W 4299 - TCCATGATCGCTCTTTGATG M|1439|I M|1439|I D|1440|H D|1440|N 0 0 0 0 0.3384654881033673 P21951 0.4067501425743103 0.4067501425743103 0.0812620222568512 0.330893337726593 48.73548172994572 45.0 1.0 no 11359 chrXIV_152547 29503 essential YNL262W 4335 + ACGTTCCGCTCAAAAGCAAT T|1446|R T|1446|M F|1447|L silent|TTC>TTT|F|1447 0 0 0 0 -0.3114679551711741 P21951 0.5160285830497742 0.15098991990089414 0.7987997531890869 46.23373362809247 45.0 1.0 no 11360 chrXIV_152552r 29506 essential YNL262W 4343 - ACGCACCCATTGCTTTTGAG A|1454|P A|1454|T silent|GCG>GCC|A|1454 silent|GCG>GCA|A|1454 0 0 0 0 -0.4766449782695938 P21951 0.3107633590698242 0.7759478688240051 52.65421654815622 50.0 1.0 no 11361 chrXIV_152673 29509 essential YNL262W 4461 + CTACATTTCCCAACATCAAT H|1489|D H|1489|Y 0 0 0 0 -0.29320470008359995 P21951 0.014965868555009363 0.23107028007507324 43.8082798516429 35.0 1.0 no 11362 chrXIV_152994 29510 essential YNL262W 4782 + CCGTTTATCACTAAGCTCTT P|1595|R P|1595|L 0 0 0 0 -0.5820246508552771 P21951 0.3800658285617829 0.2598526179790497 47.86866793658288 40.0 1.0 no 11363 chrXIV_153070 29513 essential YNL262W 4858 + TTCTTCTACCCCAATTGAAC L|1621|V L|1621|F L|1622|V silent|CTA>TTA|L|1622 0 0 0 0 0.5954531051049975 P21951 0.2954169809818268 0.0734291821718216 0.4465411603450775 46.8323185244966 40.0 1.0 no 11364 chrXIV_153078r 29514 essential YNL262W 4869 - GTCGGTTGCCAGTTCAATTG silent|CCG>CCC|P|1629 silent|CCG>CCA|P|1629 0 0 0 0 1.3584100633525726 P21951 51.962212622498605 50.0 1.0 no 11365 chrXIV_153079r 29515 essential YNL262W 4870 - TGTCGGTTGCCAGTTCAATT silent|CCG>CCC|P|1629 silent|CCG>CCA|P|1629 0 0 0 0 -0.8512521712375541 P21951 51.96221262249856 45.0 1.0 no 11366 chrXIV_153124 29516 essential YNL262W 4912 + ACGTTTTATCCAGTGGTTCG H|1638|Q silent|CAC>CAT|H|1638 0 0 0 0 0.03893727661977886 P21951 0.28019356727600103 49.8111510109058 45.0 1.0 no 11367 chrXIV_153181 29518 essential YNL262W 4969 + ACATTCCAATCTGTAATTTG N|1657|K silent|AAC>AAT|N|1657 P|1659|A P|1659|S 0 0 0 0 0.8486921728436716 P21951 0.08320941776037216 0.0 0.0 39.72000193406228 30.0 1.0 no 11368 chrXIV_153185 29519 essential YNL262W 4973 + TCCAATCTGTAATTTGAGGC P|1659|R P|1659|L P|1659|A P|1659|S 0 0 0 0 -0.8369827156511441 P21951 0.0 0.0 0.0 0.0 44.921262300052774 40.0 1.0 no 11369 chrXIV_155110 29520 essential YNL261W 10 + CCACTCCGGAAGTTGCTTTT T|5|S T|5|I silent|ACC>ACG|T|4 silent|ACC>ACT|T|4 ORC5 Origin Recognition Complex 479.0 0 0 0 0 0.03188107817810065 P50874 0.9103760123252868 0.9084240198135376 0.5807116627693176 0.43693771958351135 53.547887962623406 50.0 1.0 no 11370 chrXIV_155110r 29521 essential YNL261W 13 - CCTAAAAGCAACTTCCGGAG R|11|T R|11|K ORC5 Origin Recognition Complex 479.0 0 0 0 0 -0.30050881239126165 P50874 0.979092001914978 0.9988390207290648 0.0 0.0 45.41611676993034 50.0 1.0 no 11371 chrXIV_155187 29523 essential YNL261W 87 + CCTTCAAATTTAATCTTGCA P|30|R P|30|L S|31|* S|31|L ORC5 Origin Recognition Complex 479.0 0 0 0 0 -0.08190894864797646 P50874 0.9074479937553406 0.9137349724769592 0.9575160145759584 0.04310600087046623 0.022851968184113503 0.7734086513519287 41.04213359913905 30.0 1.0 no 11372 chrXIV_155381 29527 essential YNL261W 281 + CACAGATTACGATCCTTTAC T|95|R T|95|I ORC5 Origin Recognition Complex 479.0 0 0 0 0 0.2383014141656101 P50874 0.8989629745483398 0.9091619849205016 0.4017589092254639 0.1425219029188156 43.25939597079571 40.0 1.0 no 11373 chrXIV_155474 29530 essential YNL261W 374 + GACTTGCTTGTTCTTGATAT T|126|S T|126|I C|127|W silent|TGC>TGT|C|127 ORC5 Origin Recognition Complex 479.0 0 0 0 0 0.5296004682553207 P50874 0.9103760123252868 0.9084240198135376 0.8880190253257751 0.8292768001556396 0.5657293796539307 0.017069548368453983 45.20912761720326 35.0 1.0 no 11374 chrXIV_155667r 29532 essential YNL261W 570 - ACTTCGTCCACATTATACCT V|197|L V|197|I E|196|Q E|196|K ORC5 Origin Recognition Complex 479.0 0 0 0 0 -1.0491983841784194 P50874 0.9131360054016112 0.9208049774169922 0.9202449917793274 0.9081959724426271 0.4918233156204224 0.926604390144348 0.5034279823303223 0.03483211249113083 49.55856333312874 40.0 1.0 no 11375 chrXIV_155813 29534 essential YNL261W 713 + CTTCATTCACTTAATTGTGC F|239|L silent|TTC>TTT|F|239 ORC5 Origin Recognition Complex 479.0 0 0 0 0 0.6355580931367859 P50874 0.9029620289802552 0.03996830806136131 42.969438452595064 35.0 1.0 no 11376 chrXIV_156028r 29536 essential YNL261W 931 - CTCAAGGTCATCACGATTTG E|317|Q E|317|K ORC5 Origin Recognition Complex 479.0 0 0 0 0 0.8935627928978739 P50874 0.97645902633667 0.9644089937210084 0.5691237449645996 0.8962216377258301 44.78879153166906 45.0 1.0 no 11377 chrXIV_156101 29537 essential YNL261W 1001 + CTCATATATTTGTTCATATC S|335|* S|335|L ORC5 Origin Recognition Complex 479.0 0 0 0 0 -1.1909601046177123 P50874 0.9508730173110962 0.007620013318955898 37.79431366584527 25.0 1.0 no 11378 chrXIV_156168 29540 essential YNL261W 1068 + ATACAAGGTAGAGCTGCTTA Q|358|E Q|358|* ORC5 Origin Recognition Complex 479.0 0 0 0 0 -0.2649932204879365 P50874 0.9365779757499696 0.2095368653535843 45.345721396525725 40.0 1.0 no 11379 chrXIV_157105 29541 essential YNL260C 331 - ACCTTTCATTAAAGTACGAA G|117|R G|117|S G|117|A G|117|D 0 0 0 0 0.6373990950658805 P53846 0.5245961546897888 0.7644181847572327 0.7141911387443542 0.6166039705276489 38.6753050485999 30.0 0.0 no 11380 chrXIV_157185 29542 essential YNL260C 251 - ACAAACCTTCCATTTGTCCC L|90|F silent|TTG>TTA|L|90 G|89|A G|89|D 0 0 0 0 0.4191755043080295 P53846 0.1060548946261406 0.35664644837379456 0.024195069447159767 51.722168915574166 45.0 0.0 no 11381 chrXIV_157203r 29544 essential YNL260C 230 + ATTCCAAAGATTTACGCTCC F|78|L silent|TTC>TTT|F|78 Q|79|E Q|79|* 0 0 0 0 0.07837776775279133 P53846 0.045073386281728745 0.0 45.717267391325656 40.0 0.0 no 11382 chrXIV_157263 29547 essential YNL260C 173 - TCTGCTTTATATTCTCATTC Q|64|H silent|CAG>CAA|Q|64 K|63|N silent|AAG>AAA|K|63 0 0 0 0 -0.1887808554763576 P53846 0.6195110678672789 0.03994273394346237 43.398234314636 30.0 0.0 no 11383 chrXIV_158745r 29551 essential YNL258C 1606 + CAGCTAATTTTTCTCACAAT A|537|G A|537|V DSL1 Dependence on SLy1-20 754.0 0 0 0 0 1.1973182519733494 P53847 0.4924470186233521 0.4920024871826172 0.8026999831199646 -0.1426600068807602 40.376543022373426 30.0 0.0 no 11384 chrXIV_158777r 29552 essential YNL258C 1574 + CCTTTTGCAGACATCGTATA L|526|V L|526|F DSL1 Dependence on SLy1-20 754.0 0 0 0 0 -0.4747629904420221 P53847 1.0 0.048190668225288384 2.0384600162506104 0.06988000124692917 47.26002107507992 40.0 0.0 no 11385 chrXIV_159143 29554 essential YNL258C 1211 - CATCTTTGGATACGGCATTA D|410|H D|410|N DSL1 Dependence on SLy1-20 754.0 0 0 0 0 0.3827806940015019 P53847 0.2027996927499771 0.2489505261182785 45.62359072004681 40.0 0.0 no 11386 chrXIV_159396 29556 essential YNL258C 958 - CCAATTGGTAACTTCTGATT W|326|S W|326|* DSL1 Dependence on SLy1-20 754.0 0 0 0 0 -0.2367463765780932 P53847 0.4814439713954926 5.095253944396973 6.244344234466553 42.797517944663866 35.0 0.0 no 11387 chrXIV_159498 29558 essential YNL258C 856 - TGCATTATTTTTCACAAATT A|292|P A|292|T DSL1 Dependence on SLy1-20 754.0 0 0 0 0 0.4101464733171958 P53847 0.24225914478302 0.4482511878013611 1.894528031349182 1.0752799510955808 2.4112799167633057 2.0619800090789795 36.4347122532468 20.0 0.0 no 11388 chrXIV_159626 29559 essential YNL258C 728 - ATACAGTAGACACACAATGT V|249|L V|249|I DSL1 Dependence on SLy1-20 754.0 0 0 0 0 0.6332339953091838 P53847 0.4549052119255066 0.4131695032119751 -0.15230000019073486 -0.8478999733924866 39.96640676831999 35.0 0.0 no 11389 chrXIV_159795 29561 essential YNL258C 559 - TCTTACCTGCTCTTGAGAGT R|193|T R|193|K V|192|L V|192|I DSL1 Dependence on SLy1-20 754.0 0 0 0 0 -0.12122494946876085 P53847 0.17613117396831512 0.6083715558052063 0.059314969927072525 0.286250114440918 1.9063999652862549 -0.012380000203847885 -0.8440200090408325 0.8606600165367126 52.01190634023186 45.0 0.0 no 11390 chrXIV_159925 29563 essential YNL258C 429 - TCTTTACCCCATTCCACTGT D|150|H D|150|N G|148|A G|148|D DSL1 Dependence on SLy1-20 754.0 0 0 0 0 0.7166525938235082 P53847 0.02283362857997417 0.07341517508029938 0.13267070055007935 0.10933447629213333 -0.06666000187397003 0.008820000104606152 3.531909942626953 3.6539459228515625 56.352651595101975 45.0 0.0 no 11391 chrXIV_159924 29564 essential YNL258C 430 - GTCTTTACCCCATTCCACTG D|150|H D|150|N DSL1 Dependence on SLy1-20 754.0 0 0 0 0 -0.06933078278789859 P53847 0.02283362857997417 0.07341517508029938 -0.06666000187397003 0.008820000104606152 56.352651595101975 50.0 0.0 no 11392 chrXIV_159938r 29565 essential YNL258C 413 + CATCCAATTTACGCCCACAG I|139|M silent|ATC>ATT|I|139 Q|140|E Q|140|* DSL1 Dependence on SLy1-20 754.0 0 0 0 0 -0.7614444580903796 P53847 0.011758578009903431 0.4869887232780457 0.6614599823951721 1.3402199745178225 50.633115245583035 50.0 0.0 no 11393 chrXIV_160206 29566 essential YNL258C 148 - ATCTAGGATGTTCAGTTCGT D|56|H D|56|N DSL1 Dependence on SLy1-20 754.0 0 0 0 0 -0.5861204843010901 P53847 0.15292413532733914 0.8442830443382263 -0.0057799997739493856 0.007180000189691781 48.10593116115081 40.0 0.0 no 11394 chrXIV_164656 29569 essential YNL256W 33 + AGACATAGTGTACCACTAGG H|13|D H|13|Y FOL1 FOLic acid synthesis 824.0 0 1 0 0 -0.5504853514799434 P53848 46.09191684623697 45.0 1.0 no 11395 chrXIV_164755r 29570 essential YNL256W 135 - AAGCTTAGTAGACATTTCTG S|51|T S|51|N FOL1 FOLic acid synthesis 824.0 0 0 0 0 0.4526565426743265 P53848 0.1603056788444519 0.015761531889438633 41.13860279453705 35.0 1.0 no 11396 chrXIV_164764 29571 essential YNL256W 141 + TGTCTACTAAGCTTAGATAT L|49|V silent|CTA>TTA|L|49 L|50|V silent|CTA>TTA|L|50 FOL1 FOLic acid synthesis 824.0 0 0 0 0 0.2723082415546509 P53848 0.6063478589057922 0.84573894739151 39.90305017782981 30.0 1.0 no 11397 chrXIV_164787 29572 essential YNL256W 164 + TACAGATTTTAGTAAATCTG T|56|R T|56|I FOL1 FOLic acid synthesis 824.0 0 0 0 0 -0.6122669370238798 P53848 0.006711642257869244 0.010882610455155373 33.62480865655641 25.0 1.0 no 11398 chrXIV_165176r 29577 essential YNL256W 556 - TTGCACTGGCGGTGGCAATT silent|GTG>GTC|V|191 silent|GTG>GTA|V|191 V|191|L V|191|M FOL1 FOLic acid synthesis 824.0 0 0 0 0 1.0069029709557942 P53848 0.4604725539684296 0.15080519020557406 54.66291909176175 55.00000000000001 1.0 no 11399 chrXIV_165187r 29578 essential YNL256W 567 - TCAATTATGCTTTGCACTGG D|196|H D|196|N FOL1 FOLic acid synthesis 824.0 0 0 0 0 0.007394928339286497 P53848 0.11106058210134506 0.6189895868301392 45.3058952993764 40.0 1.0 no 11400 chrXIV_165288r 29579 essential YNL256W 668 - ACTTTTGAAAATACTCGTTA K|229|N silent|AAG>AAA|K|229 FOL1 FOLic acid synthesis 824.0 0 0 0 0 0.8571960507266899 P53848 0.4966354668140411 35.62186066075185 25.0 1.0 no 11401 chrXIV_165349 29580 essential YNL256W 726 + AACGCAATCACAGCCACAGA N|243|K silent|AAC>AAT|N|243 A|244|G A|244|V FOL1 FOLic acid synthesis 824.0 0 0 0 0 0.3993868149613552 P53848 0.014705018140375612 0.0 0.0 48.437171322174045 50.0 1.0 no 11402 chrXIV_165355 29582 essential YNL256W 732 + ATCACAGCCACAGAAGGTGT I|245|M silent|ATC>ATT|I|245 T|246|R T|246|I FOL1 FOLic acid synthesis 824.0 0 0 0 0 0.6281936551790253 P53848 0.017948566004633904 0.03927606344223023 0.0989028662443161 51.31824951136281 50.0 1.0 no 11403 chrXIV_165381 29583 essential YNL256W 758 + AAGCTGTATTAGAGAGCCCA S|254|R silent|AGC>AGT|S|254 FOL1 FOLic acid synthesis 824.0 0 0 0 0 -1.4672464389156987 P53848 0.0297719594091177 50.23008151299979 45.0 1.0 no 11404 chrXIV_165478 29585 essential YNL256W 855 + TCACAAAACACTCCTATTGA Q|287|E Q|287|* S|286|* S|286|L FOL1 FOLic acid synthesis 824.0 0 1 0 0 -0.6720787483200135 P53848 1.0 0.7937552928924559 40.57640325081974 35.0 1.0 no 11405 chrXIV_165477 29586 essential YNL256W 854 + ATCACAAAACACTCCTATTG S|286|* S|286|L Q|287|E Q|287|* FOL1 FOLic acid synthesis 824.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.3247841838548297 P53848 0.7937552928924559 1.0 39.45051598363085 35.0 1.0 no 11406 chrXIV_165527 29587 essential YNL256W 904 + TAGCGTTTGGTTCAAACATT A|303|G A|303|V FOL1 FOLic acid synthesis 824.0 0 0 0 0 -1.8387840102642712 P53848 0.03930933400988579 0.01323542557656765 43.13429963808136 35.0 1.0 no 11407 chrXIV_165658 29591 essential YNL256W 1035 + GATCAAACCCCTTTCATGAA Q|347|E Q|347|* FOL1 FOLic acid synthesis 824.0 0 0 0 0 -0.3503939047529072 P53848 0.0 45.851453327904274 40.0 1.0 no 11408 chrXIV_165659 29592 essential YNL256W 1036 + ATCAAACCCCTTTCATGAAT Q|347|E Q|347|* T|348|S T|348|I FOL1 FOLic acid synthesis 824.0 0 0 0 0 0.6888004050657957 P53848 0.0 0.6881293654441833 0.17552217841148374 44.74471939477354 35.0 1.0 no 11409 chrXIV_165665r 29593 essential YNL256W 1045 - AACACACCCATTCATGAAAG V|355|L V|355|I C|354|S C|354|Y FOL1 FOLic acid synthesis 824.0 0 0 0 0 0.6238116909669891 P53848 0.5021684765815735 0.5103670954704285 0.046481195837259286 0.007404330186545849 41.7508161056569 40.0 1.0 no 11410 chrXIV_165666r 29594 essential YNL256W 1046 - CAACACACCCATTCATGAAA V|355|L V|355|I C|354|S C|354|Y FOL1 FOLic acid synthesis 824.0 0 0 0 0 -0.7782322062048801 P53848 0.5021684765815735 0.5103670954704285 0.046481195837259286 0.007404330186545849 42.90327251401789 40.0 1.0 no 11411 chrXIV_165667r 29595 essential YNL256W 1047 - TCAACACACCCATTCATGAA E|356|Q E|356|K V|355|L V|355|I FOL1 FOLic acid synthesis 824.0 0 0 0 0 -0.03035847694949712 P53848 0.07605859637260437 1.0 0.5021684765815735 0.5103670954704285 45.15306244679329 40.0 1.0 no 11412 chrXIV_165708r 29597 essential YNL256W 1088 - ACAATTTTAATAATTCGCTT L|369|F silent|TTG>TTA|L|369 FOL1 FOLic acid synthesis 824.0 0 0 0 0 0.707222049266842 P53848 0.5529575347900391 35.044101684929785 20.0 1.0 no 11413 chrXIV_165709r 29598 essential YNL256W 1089 - CACAATTTTAATAATTCGCT L|369|F silent|TTG>TTA|L|369 FOL1 FOLic acid synthesis 824.0 0 0 0 0 0.6207859274181249 P53848 0.5529575347900391 36.1183290948494 25.0 1.0 no 11414 chrXIV_165868r 29599 essential YNL256W 1248 - CTCTCCAGCATTCTAGGATG E|422|D silent|GAG>GAA|E|422 E|422|Q E|422|K FOL1 FOLic acid synthesis 824.0 0 0 0 0 1.16463154758541 P53848 0.15776996314525604 0.02529319189488888 0.019903939217329025 51.54103222638463 50.0 1.0 no 11415 chrXIV_165933 29602 essential YNL256W 1310 + TCACCTTCATCCTGTGACAG H|438|Q silent|CAC>CAT|H|438 H|438|D H|438|Y FOL1 FOLic acid synthesis 824.0 0 0 0 0 0.4593808836373578 P53848 0.3026599586009979 0.21557866036891934 1.0 52.616774357535064 50.0 1.0 no 11416 chrXIV_165969r 29605 essential YNL256W 1349 - TGTCGTATAACTGTTTTAAA D|456|H D|456|N FOL1 FOLic acid synthesis 824.0 0 0 0 0 0.5577326345346432 P53848 0.11380968987941742 0.5274440050125122 36.0803643444292 25.0 1.0 no 11417 chrXIV_165995 29606 essential YNL256W 1372 + AGCATGATGAAGATACCTTA H|459|D H|459|Y FOL1 FOLic acid synthesis 824.0 0 0 0 0 -0.2342536597290961 P53848 0.6552239656448364 0.26590585708618164 41.726068135154826 35.0 1.0 no 11418 chrXIV_166024 29607 essential YNL256W 1401 + GTTCCATTGCCTTATCGTAG P|469|A P|469|S P|469|R P|469|L FOL1 FOLic acid synthesis 824.0 0 0 0 0 0.1327774622220673 P53848 0.3323138654232025 0.28189179301261896 0.18907615542411804 0.1265505850315094 51.816847763355206 45.0 1.0 no 11419 chrXIV_166033r 29609 essential YNL256W 1413 - GGCTCCACACCACTACGATA E|477|D silent|GAG>GAA|E|477 E|477|Q E|477|K FOL1 FOLic acid synthesis 824.0 0 0 0 0 0.6486769271352922 P53848 0.6269067525863647 0.6056799292564392 0.934050679206848 54.102972814131995 55.00000000000001 1.0 no 11420 chrXIV_166175r 29611 essential YNL256W 1555 - CGCAAAATGCTCACCTCCAT A|525|P A|525|T FOL1 FOLic acid synthesis 824.0 0 0 0 0 0.013400214962848713 P53848 0.2749999761581421 0.5726051926612854 50.180686299619474 50.0 1.0 no 11421 chrXIV_166299 29615 essential YNL256W 1676 + TAACTCTATTCAGGCGTCTG N|560|K silent|AAC>AAT|N|560 S|561|C S|561|F FOL1 FOLic acid synthesis 824.0 0 0 0 0 0.2934733869101124 P53848 0.164117231965065 0.0 0.0 46.94374379326911 45.0 1.0 no 11422 chrXIV_166345r 29617 essential YNL256W 1725 - TCTCTAATGGCCTTAATTAA R|581|T R|581|K E|582|Q E|582|K FOL1 FOLic acid synthesis 824.0 0 0 0 0 0.3396306097429085 P53848 0.12053023278713225 0.2389435917139053 0.6805750131607056 0.7980754375457764 40.95951104137794 30.0 1.0 no 11423 chrXIV_166358r 29618 essential YNL256W 1738 - TAACTCAGTGCTTTCTCTAA E|585|D silent|GAG>GAA|E|585 E|585|Q E|585|K FOL1 FOLic acid synthesis 824.0 0 0 0 0 0.44431626059819374 P53848 0.5249553918838501 0.3738674819469452 0.7295230031013489 43.778925086491306 35.0 1.0 no 11424 chrXIV_173029r 29621 essential YNL251C 1264 + ACAGTATTATTCCTATGCAC Y|422|* silent|TAC>TAT|Y|422 NRD1 Nuclear pre-mRNA Down-regulation 575.0 0 0 0 0 -0.6184811832687879 P53617 44.47243538983844 35.0 0.0 no 11425 chrXIV_173093 29623 essential YNL251C 1203 - ACTCCCCACCTAGTTCTCAA G|407|A G|407|E V|408|L V|408|I NRD1 Nuclear pre-mRNA Down-regulation 575.0 0 0 0 0 -1.8800257312568969 P53617 0.4594200253486633 0.011807587929069996 0.0 0.0 0.4171999990940094 0.7573999762535095 -0.5776000022888184 -0.5428000092506409 57.19195765538206 50.0 0.0 no 11426 chrXIV_173098 29627 essential YNL251C 1198 - CCACCTAGTTCTCAATGGCA R|405|S silent|AGG>AGA|R|405 W|406|S W|406|* NRD1 Nuclear pre-mRNA Down-regulation 575.0 0 0 0 0 -2.345046324641812 P53617 0.0 0.0 0.6567999720573425 2.5592000484466557 53.702129481968605 50.0 0.0 yes 11427 chrXIV_173098r 29628 essential YNL251C 1195 + CCCTGCCATTGAGAACTAGG L|400|V silent|CTG>TTG|L|400 silent|GCC>GCG|A|399 silent|GCC>GCT|A|399 NRD1 Nuclear pre-mRNA Down-regulation 575.0 0 0 0 0 0.4815303694572077 P53617 0.5001620054244995 0.5526000261306763 52.480552270033684 55.00000000000001 0.0 no 11428 chrXIV_173101r 29629 essential YNL251C 1192 + GAGCCCTGCCATTGAGAACT A|399|G A|399|V silent|GCC>GCG|A|399 silent|GCC>GCT|A|399 NRD1 Nuclear pre-mRNA Down-regulation 575.0 0 0 0 0 -0.5742241687247187 P53617 0.056608274579048164 0.03714317083358765 0.3050000071525574 0.6100000143051147 55.46701833019273 55.00000000000001 0.0 no 11429 chrXIV_173123r 29630 essential YNL251C 1170 + TTGCAAAACTTCAATAAAGA Q|392|E Q|392|* NRD1 Nuclear pre-mRNA Down-regulation 575.0 0 0 0 0 0.6977047807068653 P53617 1.0 0.5748000144958496 32.3593164540074 25.0 0.0 no 11430 chrXIV_173176 29631 essential YNL251C 1120 - TTTCACAAAAGCGTGTTTTC silent|GTG>GTC|V|379 silent|GTG>GTA|V|379 V|379|L V|379|M NRD1 Nuclear pre-mRNA Down-regulation 575.0 0 0 0 0 -0.2591768113683659 P53617 0.0 0.0 1.3614000082015991 0.27880001068115234 41.06692076157663 35.0 0.0 no 11431 chrXIV_173213 29632 essential YNL251C 1083 - ACGCTTTGTACTTCAGCAAA S|367|T S|367|N V|368|L V|368|I NRD1 Nuclear pre-mRNA Down-regulation 575.0 0 0 0 0 -0.4963395681827661 P53617 0.0 0.0 0.0 0.0 -0.0926000028848648 0.6934000253677368 0.10040000081062317 -0.6769999861717224 45.63781551837138 40.0 0.0 no 11432 chrXIV_173281r 29634 essential YNL251C 1012 + GCCGTACTCTTTTCATCGGT R|339|G R|339|C S|338|R silent|AGC>AGT|S|338 NRD1 Nuclear pre-mRNA Down-regulation 575.0 0 0 0 0 -2.7956548337609832 P53617 0.0 0.0 0.0 0.5795999765396118 0.18440000712871552 -0.7576000094413757 55.33589913238416 50.0 0.0 yes 11433 chrXIV_173489r 29643 essential YNL251C 804 + CCATTTTCTCAGCCATCGAC P|269|R P|269|L NRD1 Nuclear pre-mRNA Down-regulation 575.0 0 1 0 0 -0.2801628330807018 P53617 0.20425304770469666 0.11583191156387328 52.879227753734206 50.0 0.0 no 11434 chrXIV_173572 29645 essential YNL251C 724 - TTCACGTCTGCTACCATATT E|248|Q E|248|K R|247|P R|247|H NRD1 Nuclear pre-mRNA Down-regulation 575.0 0 0 0 0 0.34298876420633345 P53617 0.5841192603111267 0.9197584986686708 0.331064909696579 0.1390247344970703 49.014525384482 40.0 0.0 no 11435 chrXIV_173627r 29651 essential YNL251C 666 + TTGCCTTCACATACATCCGT P|224|A P|224|S P|224|R P|224|L NRD1 Nuclear pre-mRNA Down-regulation 575.0 0 0 0 0 -1.0023348509441623 P53617 0.970467448234558 0.6571745872497559 0.07409247756004332 0.05940574407577515 52.696247269280946 45.0 0.0 no 11436 chrXIV_173664 29652 essential YNL251C 632 - TCTGCAGAGCCGCTATTACT Q|217|H silent|CAG>CAA|Q|217 silent|CTG>CTC|L|216 silent|CTG>CTA|L|216 NRD1 Nuclear pre-mRNA Down-regulation 575.0 0 0 0 0 0.31921636887498217 P53617 0.01045540813356638 53.98673340585565 50.0 0.0 no 11437 chrXIV_173673r 29653 essential YNL251C 620 + AGCTCTTTTCCAAGTAATAG A|208|G A|208|V L|209|V L|209|F NRD1 Nuclear pre-mRNA Down-regulation 575.0 0 0 0 0 -0.13107899726227634 P53617 0.2353793978691101 0.11884782463312148 0.04924917221069336 0.028932496905326843 42.924959499250576 35.0 0.0 no 11438 chrXIV_173738 29656 essential YNL251C 558 - AGACTTATGTTCAAGTTTAA S|192|T S|192|N NRD1 Nuclear pre-mRNA Down-regulation 575.0 0 0 0 0 0.16000053701174247 P53617 0.4044485092163086 0.23817798495292666 36.792146975484506 25.0 0.0 no 11439 chrXIV_173811r 29658 essential YNL251C 482 + CGCTTCACAACAACTATCAC A|162|G A|162|V S|163|* S|163|L NRD1 Nuclear pre-mRNA Down-regulation 575.0 0 0 0 0 -0.5238284909638892 P53617 0.5004234910011292 0.25537195801734924 0.13388913869857788 43.48312836351016 45.0 0.0 no 11440 chrXIV_173917r 29660 essential YNL251C 376 + TGCTTTTAGACATTTGGGAC L|127|V L|127|F NRD1 Nuclear pre-mRNA Down-regulation 575.0 0 0 0 0 0.4859009118693876 P53617 0.0 0.0 2.1157000064849854 2.492360115051269 1.479159951210022 3.2978758811950684 44.92757785826161 40.0 0.0 no 11441 chrXIV_173922r 29662 essential YNL251C 371 + TCGTATGCTTTTAGACATTT R|125|G R|125|C NRD1 Nuclear pre-mRNA Down-regulation 575.0 0 0 0 0 0.16954276427998136 P53617 0.4043336808681488 0.056050442159175866 2.1380600929260254 1.3552600145339966 42.604732428370205 30.0 0.0 no 11442 chrXIV_174004 29663 essential YNL251C 292 - TACTTCGCCCAACGTGTTTA V|104|L V|104|I E|103|Q E|103|K NRD1 Nuclear pre-mRNA Down-regulation 575.0 0 0 0 0 0.5231427591305523 P53617 0.601496160030365 0.42841315269470215 0.10280108451843263 0.09111057966947557 1.2076599597930908 1.3751399517059326 -0.4282999932765961 -0.7264999747276306 50.803830268261954 45.0 0.0 no 11443 chrXIV_174084r 29665 essential YNL251C 209 + TTCAATAGGTAGAGCTTACT S|71|* S|71|L NRD1 Nuclear pre-mRNA Down-regulation 575.0 0 0 0 0 -2.7815716027517365 P53617 0.0 -2.5039598941802983 42.81191241529871 35.0 0.0 yes 11444 chrXIV_174122 29666 essential YNL251C 174 - GAACCTAATTTATGAGAATC G|64|A G|64|D G|64|R G|64|S NRD1 Nuclear pre-mRNA Down-regulation 575.0 0 0 0 0 0.545604215507351 P53617 0.0 0.0 0.0 0.0 -1.7187000513076782 5.157760143280028 5.90500020980835 -1.5175399780273438 35.355977228955744 30.0 0.0 no 11445 chrXIV_174248r 29668 essential YNL251C 45 + TCATTCAAAGATTTGAAATC S|16|* S|16|L F|17|L silent|TTC>TTT|F|17 NRD1 Nuclear pre-mRNA Down-regulation 575.0 0 0 0 0 0.23953034211408106 P53617 0.037601955235004425 1.0 0.3856399953365326 0.2840000092983246 0.6824520230293274 32.5331929856963 25.0 0.0 no 11446 chrXIV_182895r 29669 essential YNL247W 23 - ACATTATAGTATATCTTCTC M|14|I M|14|I 767.0 0 0 0 0 -0.5047107599042008 P53852 0.9553959965705872 0.9553959965705872 0.36412733793258667 0.36412733793258667 37.847511871686265 25.0 1.0 no 11447 chrXIV_182938r 29670 essential YNL247W 66 - GGCGTTGGAACCTTCCATTT silent|ACG>ACC|T|28 silent|ACG>ACA|T|28 767.0 0 0 0 0 0.2458690047304229 P53852 53.97278686061589 50.0 1.0 no 11448 chrXIV_182959r 29672 essential YNL247W 87 - AACACAGTTTCTTTAGCTTG silent|GTG>GTC|V|35 silent|GTG>GTA|V|35 V|35|L V|35|M 767.0 0 0 0 0 0.5488082517649471 P53852 0.9539830088615416 0.9587630033493042 0.3042131066322327 0.10569680482149124 42.80988792236353 35.0 1.0 no 11449 chrXIV_183022 29673 essential YNL247W 147 + ATTCCGCAATCTGGCAATAG P|51|A P|51|S P|51|R P|51|L 767.0 0 1 0 0 -1.3192339863194102 P53852 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.1674341857433319 0.06369522958993913 0.009375381283462048 0.014078017324209213 46.9731367500089 45.0 1.0 no 11450 chrXIV_183101r 29675 essential YNL247W 229 - ATCAATAGAGACATAGTTTC D|83|H D|83|N 767.0 0 0 0 0 -4.6259545928370445 P53852 0.9486550092697144 0.956179976463318 0.0 0.0 36.86982424853278 30.0 1.0 yes 11451 chrXIV_183316 29676 essential YNL247W 441 + AACAAAAATTTTACTATTCA N|148|K silent|AAC>AAT|N|148 767.0 0 0 0 0 0.818613901556257 P53852 0.9439849853515624 0.3706071376800537 29.446276160638604 15.0 1.0 no 11452 chrXIV_183437r 29678 essential YNL247W 565 - TTCAATAGCATTTTGAACTG E|195|Q E|195|K 767.0 0 0 0 0 0.3023140271499281 P53852 0.956179976463318 0.9475290179252625 0.561305820941925 0.9108282327651978 37.603415205110934 30.0 1.0 no 11453 chrXIV_183450 29679 essential YNL247W 575 + TGCTATTGAATCAATCACTA A|193|G A|193|V 767.0 0 0 0 0 0.11003268249061984 P53852 0.9484469890594482 0.9504740238189696 0.5501843094825745 0.09618035703897476 38.96138801152108 30.0 1.0 no 11454 chrXIV_183451 29680 essential YNL247W 576 + GCTATTGAATCAATCACTAA A|193|G A|193|V 767.0 0 0 0 0 1.0176553875760772 P53852 0.9484469890594482 0.9504740238189696 0.5501843094825745 0.09618035703897476 37.60950416811483 30.0 1.0 no 11455 chrXIV_183513 29682 essential YNL247W 638 + GGACGTTACGGTTCCTCTAT D|214|E silent|GAC>GAT|D|214 767.0 0 0 0 0 -0.042484554801850025 P53852 0.9532920122146606 0.12163787335157394 52.437508607096454 50.0 1.0 no 11456 chrXIV_183575 29684 essential YNL247W 700 + TCCGCCAACTTCCAGCTTAC R|235|G R|235|C F|234|L silent|TTC>TTT|F|234 767.0 0 0 0 0 0.6476637158198084 P53852 0.8994590044021606 0.8926740288734436 0.9387490153312684 0.02719768509268761 0.004327082075178622 0.025641771033406258 56.31825369104803 55.00000000000001 1.0 no 11457 chrXIV_183576 29685 essential YNL247W 701 + CCGCCAACTTCCAGCTTACT silent|CGC>CGG|R|235 silent|CGC>CGT|R|235 R|235|G R|235|C 767.0 0 0 0 0 0.5901520775109815 P53852 0.8994590044021606 0.8926740288734436 0.02719768509268761 0.004327082075178622 56.87836165173235 55.00000000000001 1.0 no 11458 chrXIV_183647r 29689 essential YNL247W 775 - CTCAGAAACACGAGTTGTAA E|265|Q E|265|K 767.0 0 0 0 0 -0.4846360264619163 P53852 0.956179976463318 0.9475290179252625 0.0 0.0 39.75592160940499 40.0 1.0 no 11459 chrXIV_183718 29690 essential YNL247W 843 + TACGCATATGCCACTTCCGA Y|282|* silent|TAC>TAT|Y|282 A|283|G A|283|V 767.0 0 0 0 0 -0.3735969617066896 P53852 0.9484469890594482 0.9504740238189696 0.07902033627033234 0.008432455360889435 52.61711655192249 50.0 1.0 no 11460 chrXIV_183694 29691 essential YNL247W 819 + GTTCAAAAAATTATTGATAA Q|275|E Q|275|* 767.0 0 0 0 0 1.087406257288707 P53852 0.9590039849281312 1.0 27.694979024368138 15.0 1.0 no 11461 chrXIV_183728r 29693 essential YNL247W 856 - GTACACGGAACCGTCGGAAG silent|GTG>GTC|V|291 silent|GTG>GTA|V|291 V|291|L V|291|M 767.0 0 0 0 0 -0.16204269336134866 P53852 0.9539830088615416 0.9587630033493042 0.02584630437195301 0.0052340240217745295 48.61229248278289 60.0 1.0 no 11462 chrXIV_183788 29694 essential YNL247W 913 + ACTATGCTAAATGCCAGCCA D|305|E silent|GAC>GAT|D|305 A|307|G A|307|V 767.0 0 0 0 0 -0.4595801135425294 P53852 0.9532920122146606 0.9484469890594482 0.9504740238189696 1.0 0.046106770634651184 0.017182314768433567 50.126261000659724 45.0 1.0 no 11463 chrXIV_183805r 29695 essential YNL247W 933 - TCTAACTGGCCCTTATTCCA D|318|H D|318|N Q|316|H silent|CAG>CAA|Q|316 767.0 0 0 0 0 0.017445175168050053 P53852 0.9486550092697144 0.956179976463318 0.9570760130882264 0.08265804499387741 0.3308960497379303 0.03796495124697685 53.65574740847211 45.0 1.0 no 11464 chrXIV_183914r 29699 essential YNL247W 1042 - CCACTCAGGTTCACCTGCCT E|353|D silent|GAG>GAA|E|353 W|354|S W|354|* 767.0 0 0 0 0 -0.9174844928883674 P53852 0.94931298494339 0.8858469724655151 0.370722770690918 0.0 62.10240715563315 60.0 1.0 no 11465 chrXIV_183943r 29701 essential YNL247W 1071 - CCTGGTCTACCCTTACCCCA G|364|R G|364|R R|362|T R|362|K 767.0 0 0 0 0 -1.7604040323789314 P53852 0.941340982913971 0.941340982913971 0.932735025882721 0.955805003643036 0.0 0.0 0.0 0.0 63.898572554074576 60.0 1.0 no 11466 chrXIV_183961r 29703 essential YNL247W 1089 - GAACATTCAATATGCCATCC C|369|S C|369|Y 767.0 1 Series([], Name: modification, dtype: object) 0 0 0 -2.062343196622612 P53852 0.9421560168266296 0.9290120005607604 0.0 0.0 44.758800616476094 40.0 1.0 yes 11467 chrXIV_183969 29704 essential YNL247W 1094 + GCATATTGAATGTTCTGTGA H|366|D H|366|Y 767.0 0 1 0 0 0.8291151058150218 P53852 0.9473130106925964 0.9489949941635132 0.0 0.0 42.817826407099396 35.0 1.0 no 11468 chrXIV_184009 29705 essential YNL247W 1134 + TCTAACATCGATATTCATTC S|379|C S|379|F N|380|K silent|AAC>AAT|N|380 767.0 0 0 0 0 0.7327293453195891 P53852 0.945252001285553 0.9294660091400146 0.9439849853515624 0.02780135348439217 0.030214931815862656 0.9401355385780334 38.37729575881906 30.0 1.0 no 11469 chrXIV_184012 29706 essential YNL247W 1137 + AACATCGATATTCATTCAGG N|380|K silent|AAC>AAT|N|380 I|381|M silent|ATC>ATT|I|381 767.0 0 0 0 0 -0.555247087243364 P53852 0.9439849853515624 0.9598389863967896 0.9401355385780334 0.5779688358306885 39.99597984869803 35.0 1.0 no 11470 chrXIV_184062 29710 essential YNL247W 1187 + TAACGAATTGGCTCAATCCG N|397|K silent|AAC>AAT|N|397 767.0 0 1 0 0 -1.1630618652731068 P53852 0.9439849853515624 0.0 43.60046959773928 45.0 1.0 no 11471 chrXIV_184107 29712 essential YNL247W 1232 + GATCAACTATTTCTTACATA I|412|M silent|ATC>ATT|I|412 N|413|K silent|AAC>AAT|N|413 767.0 0 0 0 0 0.5787445905573516 P53852 0.9598389863967896 0.9439849853515624 0.014408822171390057 0.009916437789797785 37.04060943228797 25.0 1.0 no 11472 chrXIV_184108 29713 essential YNL247W 1233 + ATCAACTATTTCTTACATAC I|412|M silent|ATC>ATT|I|412 N|413|K silent|AAC>AAT|N|413 767.0 0 0 0 0 0.19604678306842754 P53852 0.9598389863967896 0.9439849853515624 0.014408822171390057 0.009916437789797785 36.24711242245365 25.0 1.0 no 11473 chrXIV_184125 29714 essential YNL247W 1250 + TACGGGCCATTTACATATTG T|418|R T|418|M silent|GGC>GGG|G|419 silent|GGC>GGT|G|419 767.0 0 0 0 0 -1.9498679422741128 P53852 0.9476869702339172 0.9502379894256592 0.05643395707011223 0.3897947669029236 45.3339988961024 40.0 1.0 no 11474 chrXIV_184126 29715 essential YNL247W 1251 + ACGGGCCATTTACATATTGA T|418|R T|418|M silent|GGC>GGG|G|419 silent|GGC>GGT|G|419 767.0 0 0 0 0 -1.3665325002206703 P53852 0.9476869702339172 0.9502379894256592 0.05643395707011223 0.3897947669029236 47.003843027018995 40.0 1.0 no 11475 chrXIV_184209 29716 essential YNL247W 1334 + CTCACCGCGCCAATTAAGAT S|446|* S|446|L P|447|A P|447|S 767.0 0 0 0 0 -0.7511580157431266 P53852 0.9298099875450134 0.9562489986419678 0.9498909711837769 0.01832546666264534 1.0 0.3438950181007385 49.78030518139195 50.0 1.0 no 11476 chrXIV_184218r 29717 essential YNL247W 1346 - AGGCAAAAGCCAATCTTAAT A|455|P A|455|T 767.0 0 0 0 0 -1.4314791026912952 P53852 0.9573720097541808 0.9523990154266356 0.01042103674262762 0.015935298055410385 40.780041293880004 35.0 1.0 no 11477 chrXIV_184229 29718 essential YNL247W 1354 + TGGCTTTTGCCTCAGTACAA A|453|G A|453|V 767.0 0 0 0 0 -0.02668287331568376 P53852 0.9484469890594482 0.9504740238189696 0.3160644769668579 0.6614031791687012 51.892075806406744 45.0 1.0 no 11478 chrXIV_184251 29719 essential YNL247W 1376 + GAACAATCAATTGGATTTCA N|460|K silent|AAC>AAT|N|460 767.0 0 0 0 0 1.1696245177640845 P53852 0.9439849853515624 0.6505621671676636 37.005736572486 30.0 1.0 no 11479 chrXIV_184284r 29720 essential YNL247W 1412 - TTTCAAATGACTTTACTTCA E|477|Q E|477|K 767.0 0 0 0 0 0.3456348243196037 P53852 0.956179976463318 0.9475290179252625 0.0 0.0 37.32633653111083 25.0 1.0 no 11480 chrXIV_184513 29723 essential YNL247W 1638 + AACACATACATTACCACTGC N|547|K silent|AAC>AAT|N|547 T|548|R T|548|I 767.0 0 0 0 0 -0.4280194707724449 P53852 0.9439849853515624 0.9476869702339172 0.9472420215606691 0.0 0.15620535612106326 0.485438346862793 43.69189895154517 40.0 1.0 no 11481 chrXIV_186487 29726 essential YNL245C 379 - CTTCTTCTTCTGCGAACTTA K|132|N silent|AAG>AAA|K|132 K|131|N silent|AAG>AAA|K|131 CWC25 Complexed With Cef1p 179.0 0 1 0 0 0.3675400491179183 P53854 0.32659560441970825 0.20823322236537933 46.80709966763471 40.0 0.0 no 11482 chrXIV_186546r 29730 essential YNL245C 317 + ACCTGCAACACCGCCTGTAA P|107|R P|107|L P|107|A P|107|S CWC25 Complexed With Cef1p 179.0 0 1 0 0 0.3448245727077518 P53854 0.2437555342912674 0.14336979389190674 0.3950877189636231 0.3433348536491394 54.65544932020339 55.00000000000001 0.0 no 11483 chrXIV_186787 29738 essential YNL245C 79 - TTCGGTAATTAGATCCTGTT E|33|Q E|33|K CWC25 Complexed With Cef1p 179.0 0 0 0 0 1.3314029673166914 P53854 0.0 0.0 44.947587146479066 35.0 0.0 no 11484 chrXIV_187340 29740 essential YNL244C 137 - TCTTTAAATCATATTCCTCT K|52|N silent|AAG>AAA|K|52 SUI1 SUppressor of Initiator codon 108.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.6042602855547515 P32911 0.04582306370139122 -0.2700600028038025 0.8510400056838989 40.34231110898139 25.0 0.0 no 11485 chrXIV_187339 29741 essential YNL244C 138 - CTCTTTAAATCATATTCCTC K|52|N silent|AAG>AAA|K|52 SUI1 SUppressor of Initiator codon 108.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.6090035313282572 P32911 0.04582306370139122 -0.2700600028038025 0.8510400056838989 40.342311108981335 30.0 0.0 no 11486 chrXIV_187444 29743 essential YNL244C 33 - TCGTCTCCTGTGTCGGCGAA D|18|H D|18|N D|17|H D|17|N SUI1 SUppressor of Initiator codon 108.0 0 1 0 0 -2.487454228080538 P32911 0.10399066656827928 0.5049061179161072 0.03663691878318786 0.3592456579208374 -2.126579999923706 -0.1423799991607666 0.9118000268936156 0.4684000015258789 57.25362318231902 60.0 0.0 yes 11487 chrXIV_198891 29748 essential YNL240C 1067 - TCAGTTTACGCACCAGATTT silent|CTG>CTC|L|362 silent|CTG>CTA|L|362 0 0 0 0 0.7572418375125239 P23503 48.11401895494879 40.0 0.0 no 11488 chrXIV_199008 29755 essential YNL240C 950 - GAACTATCATCTGACTTCCT V|323|L V|323|I 0 0 0 0 0.4082792878823928 P23503 0.9539830088615416 0.9574310183525084 0.6555194258689879 0.4013210535049439 46.11931256100542 40.0 0.0 no 11489 chrXIV_199025r 29757 essential YNL240C 930 + GCTGTCCAACGACTACACCC A|311|G A|311|V silent|GTC>GTG|V|312 silent|GTC>GTT|V|312 0 0 0 0 -0.2136155487715317 P23503 0.9484469890594482 0.9504740238189696 0.4206490218639374 0.5670842528343201 55.536464158145115 60.0 0.0 no 11490 chrXIV_199073r 29759 essential YNL240C 882 + TCGAATCTGGGAGGCACTTG S|295|W S|295|L L|297|V silent|CTG>TTG|L|297 0 0 0 0 -1.7573034930757716 P23503 0.9288619756698608 0.9298099875450134 0.9512209892272948 0.022793455049395558 0.1721734255552292 0.38159799575805664 49.7697862121289 55.00000000000001 0.0 no 11491 chrXIV_199155r 29768 essential YNL240C 800 + CTTCAAGTCGTTTCTTACTG F|268|L silent|TTC>TTT|F|268 0 0 0 0 0.05173269478766801 P23503 0.9387490153312684 1.0 44.701893892213384 40.0 0.0 no 11492 chrXIV_199196 29769 essential YNL240C 762 - AACATTGTCACTATTTCACG M|260|I M|260|I 0 0 0 0 0.8592404624777289 P23503 0.9553959965705872 0.9553959965705872 0.3713537454605103 0.3713537454605103 40.82526407896989 35.0 0.0 no 11493 chrXIV_199291 29773 essential YNL240C 667 - CATCAGCGACAGATGGTAAA silent|CTG>CTC|L|228 silent|CTG>CTA|L|228 silent|TCG>TCC|S|227 silent|TCG>TCA|S|227 0 0 0 0 0.5746908809877823 P23503 43.39266529901352 45.0 0.0 no 11494 chrXIV_199379 29775 essential YNL240C 579 - GACTTGACATTGAGCAGCAT K|199|N silent|AAG>AAA|K|199 0 0 0 0 0.6494373183890048 P23503 0.9355990290641784 0.0 47.488284077687815 45.0 0.0 no 11495 chrXIV_199424 29777 essential YNL240C 534 - TCCGTGTATATAAGAAATCC silent|ACG>ACC|T|184 silent|ACG>ACA|T|184 E|185|Q E|185|K 0 0 0 0 -0.5725572568922674 P23503 0.956179976463318 0.9475290179252625 0.0 0.0 40.46440304296175 35.0 0.0 no 11496 chrXIV_199443r 29778 essential YNL240C 512 + TCTATTATCTGCTGTGTGTC L|172|V silent|CTA>TTA|L|172 0 0 0 0 -0.056653641975292074 P23503 0.9512209892272948 0.5784144401550293 48.45918079309513 40.0 0.0 no 11497 chrXIV_199504 29780 essential YNL240C 454 - ATGCGCAATGATCTTCTCTA silent|GCG>GCC|A|157 silent|GCG>GCA|A|157 A|157|P A|157|T 0 0 0 1 -0.142897913614177 P23503 0.9573720097541808 0.9523990154266356 0.12617263197898865 0.3699457347393036 46.84707205285394 40.0 0.0 no 11498 chrXIV_199566r 29782 essential YNL240C 389 + GCATTTCCAGTGCAAGTATA H|131|D H|131|Y F|132|L silent|TTC>TTT|F|132 0 0 0 0 0.08252080474759338 P23503 0.9473130106925964 0.9489949941635132 0.9387490153312684 0.2636652886867523 1.0 0.5376814603805542 48.48675116349398 40.0 0.0 no 11499 chrXIV_199623r 29786 essential YNL240C 332 + GTACTACGGCTTAACATTGG Y|112|* silent|TAC>TAT|Y|112 Y|113|* silent|TAC>TAT|Y|113 0 0 0 0 -4.104321322703777 P23503 45.037660222371976 45.0 0.0 yes 11500 chrXIV_199720r 29789 essential YNL240C 235 + ACTCGGTTTTCCTGAAAAAC S|80|W S|80|L H|79|Q silent|CAC>CAT|H|79 0 0 0 0 0.5359644011879943 P23503 0.9288619756698608 0.9298099875450134 0.9588389992713928 0.015936985611915592 0.2491400092840195 0.0158554594963789 41.85638342820374 40.0 0.0 no 11501 chrXIV_199884 29795 essential YNL240C 74 - CCTTCTTGCCCCCGCTCACC K|31|N silent|AAG>AAA|K|31 K|30|N silent|AAG>AAA|K|30 0 0 0 0 -0.11154535195846058 P23503 0.9355990290641784 0.9355990290641784 0.5512481927871704 0.467730462551117 68.52738264686388 70.0 0.0 no 11502 chrXIV_214941 29802 essential YNL232W 18 + TTTCCAGAAATAGCTTATCC P|8|A P|8|S P|8|R P|8|L CSL4 Cep1 Synthetic Lethal 292.0 0 0 0 0 -0.5340280884752482 P53859 2.0590200424194336 2.664299964904785 1.8634599447250368 0.6852800250053406 43.63658729846696 35.0 1.0 no 11503 chrXIV_214944r 29803 essential YNL232W 24 - TTACCTGGATAAGCTATTTC G|14|A G|14|D G|14|R G|14|S CSL4 Cep1 Synthetic Lethal 292.0 0 0 0 0 0.13290427835370872 P53859 0.0 0.0 0.0 0.0 2.9593000411987305 2.9886999130249023 2.645580053329468 3.0800800323486333 43.03376274400205 35.0 1.0 no 11504 chrXIV_214965 29804 essential YNL232W 42 + AAACTAATATGCCCACAGTA L|16|V silent|CTA>TTA|L|16 CSL4 Cep1 Synthetic Lethal 292.0 0 0 0 0 -0.17088042793082195 P53859 0.9045445919036864 1.1820800304412842 0.7871999740600586 2.441879987716675 42.42630862800291 35.0 1.0 no 11505 chrXIV_215085 29806 essential YNL232W 162 + GCTATAACTGCTACACTAGT A|55|G A|55|V CSL4 Cep1 Synthetic Lethal 292.0 0 0 0 0 0.2865720049930908 P53859 0.007714649196714163 1.0 0.7492600083351135 -1.1547000408172607 1.2488000392913818 -1.6419999599456787 1.7330000400543213 -0.31321999430656433 45.323488364456004 40.0 1.0 no 11506 chrXIV_215095 29807 essential YNL232W 172 + CTACACTAGTTGGGACAGTG T|59|R T|59|I L|60|V silent|CTA>TTA|L|60 CSL4 Cep1 Synthetic Lethal 292.0 0 0 0 0 0.4239782597279775 P53859 0.0 0.0 1.0 -1.0297399759292605 -1.4426000118255615 0.5253599882125854 0.1379999965429306 47.28546690360804 50.0 1.0 no 11507 chrXIV_215238 29809 essential YNL232W 315 + ATTCTGGTTTCAGTGCTTCC L|107|V silent|CTG>TTG|L|107 CSL4 Cep1 Synthetic Lethal 292.0 0 0 0 0 1.1208388540258956 P53859 0.996276319026947 0.6001999974250793 0.7807999849319458 54.12734144362457 45.0 1.0 no 11508 chrXIV_215239 29810 essential YNL232W 316 + TTCTGGTTTCAGTGCTTCCT L|107|V silent|CTG>TTG|L|107 CSL4 Cep1 Synthetic Lethal 292.0 0 0 0 0 0.9317734330593772 P53859 0.996276319026947 0.6001999974250793 0.7807999849319458 56.16566293439503 45.0 1.0 no 11509 chrXIV_215256r 29813 essential YNL232W 336 - TTACGACCCTTTTCTGTCCC R|118|P R|118|H G|117|A G|117|D CSL4 Cep1 Synthetic Lethal 292.0 0 0 0 0 0.8891023675729498 P53859 0.2551112473011017 0.12837256491184235 0.5121508240699768 0.20594704151153564 0.5 0.8804000020027161 56.18040608255228 50.0 1.0 no 11510 chrXIV_215319r 29816 essential YNL232W 399 - AGCACAATATCACCTTCCTT silent|GTG>GTC|V|139 silent|GTG>GTA|V|139 V|139|L V|139|M CSL4 Cep1 Synthetic Lethal 292.0 0 0 0 0 -2.96474348509112 P53859 0.0 0.0 0.3554199934005737 2.6050400733947754 49.44024581913403 40.0 1.0 yes 11511 chrXIV_215374r 29817 essential YNL232W 454 - CACAGCTAAAATTTCGACAT V|158|L V|158|M A|157|P A|157|T CSL4 Cep1 Synthetic Lethal 292.0 0 0 0 0 -0.35426111383613657 P53859 0.3542158901691437 0.021886641159653664 0.09942366182804108 0.59077388048172 0.8285199999809265 1.4921000003814695 3.590019941329956 1.171679973602295 1.6640000343322754 1.3835999965667725 3.4934000968933105 2.506200075149536 38.9435815295509 35.0 1.0 no 11512 chrXIV_215403 29818 essential YNL232W 480 + AAACCATCTCCAATTGATAG P|162|A P|162|S P|162|R P|162|L CSL4 Cep1 Synthetic Lethal 292.0 0 0 0 0 -0.584577142100297 P53859 0.6600067615509033 1.0 0.3078541755676269 0.19843821227550507 0.10822000354528427 0.13225999474525452 -0.21174000203609467 0.006039999891072512 40.48701025878876 35.0 1.0 no 11513 chrXIV_215409 29819 essential YNL232W 486 + TCTCCAATTGATAGTGGCAT P|164|A P|164|S S|163|C S|163|F CSL4 Cep1 Synthetic Lethal 292.0 0 0 0 0 -0.2779258020807089 P53859 0.8350204229354858 0.8216511011123657 0.10046979784965517 0.1974224299192429 47.53391282316608 40.0 1.0 no 11514 chrXIV_223366 29826 high_effect YNL225C 1084 - ACATAGTATTTTGTTCTGTT C|368|S C|368|Y 0 0 0 0 0.027123941657789488 P53865 0.9421560168266296 0.9290120005607604 0.7137431502342224 0.5571845769882202 41.28763884868522 25.0 0.0 no 11515 chrXIV_223657 29831 high_effect YNL225C 793 - AAACAGCTCGGCCTTTCTTA silent|CTG>CTC|L|270 silent|CTG>CTA|L|270 E|269|D silent|GAG>GAA|E|269 0 0 0 0 0.07138317901398443 P53865 0.94931298494339 0.5068230032920837 50.23683436969503 45.0 0.0 no 11516 chrXIV_223740 29832 high_effect YNL225C 710 - ACATTTCTTTATTCAGCGAA M|243|I M|243|I E|242|Q E|242|K 0 0 0 0 0.36228877731110776 P53865 0.9553959965705872 0.9553959965705872 0.956179976463318 0.9475290179252625 0.2050549238920212 0.2050549238920212 0.5670648813247681 0.858107328414917 41.48888580745529 30.0 0.0 no 11517 chrXIV_223905r 29833 high_effect YNL225C 542 + TCAAAAAAAAGTTATTGAAT Q|182|E Q|182|* 0 0 0 0 1.1749102091780173 P53865 0.9590039849281312 0.994364321231842 26.05088793267493 15.0 0.0 no 11518 chrXIV_224073r 29836 high_effect YNL225C 374 + CTCTTCGAAGCATTTTACGA S|126|C S|126|F S|127|W S|127|L 1 Series([], Name: modification, dtype: object) 0 0 0 0.44964256386928203 P53865 0.945252001285553 0.9294660091400146 0.9288619756698608 0.9298099875450134 44.16754409994638 40.0 0.0 no 11519 chrXIV_224084 29838 high_effect YNL225C 366 - TGCTTCGAAGAGTTTTCTCT K|128|N silent|AAG>AAA|K|128 silent|TCG>TCC|S|127 silent|TCG>TCA|S|127 0 1 0 0 0.53701456653959 P53865 0.9355990290641784 47.22723227150397 40.0 0.0 no 11520 chrXIV_224074r 29839 high_effect YNL225C 373 + ACTCTTCGAAGCATTTTACG S|126|C S|126|F N|125|K silent|AAC>AAT|N|125 1 Series([], Name: modification, dtype: object) 0 0 0 0.423548999268483 P53865 0.945252001285553 0.9294660091400146 0.9439849853515624 43.43864306291914 40.0 0.0 no 11521 chrXIV_224294 29843 high_effect YNL225C 156 - TTGCAATTGATGACATCTTC C|58|S C|58|Y 0 0 0 0 0.013122099878985966 P53865 0.9421560168266296 0.9290120005607604 41.364819428915844 35.0 0.0 no 11522 chrXIV_224355 29845 high_effect YNL225C 95 - TTTCATTTAGCCAGTTTTGT E|38|Q E|38|K 0 0 0 0 -0.21936802844678305 P53865 0.956179976463318 0.9475290179252625 46.9402852845791 30.0 0.0 no 11523 chrXIV_229141 29848 essential YNL222W 47 + ATCAAACAACAATCGTTCAA S|17|* S|17|L N|18|K silent|AAC>AAT|N|18 SSU72 Suppressor of SUa7, gene 2 206.0 0 0 0 0 -2.9168319231838606 P53538 0.627610981464386 0.451108992099762 0.00249657710082829 0.004989247303456068 35.76914022069593 30.0 1.0 yes 11524 chrXIV_229190 29849 essential YNL222W 96 + GGCTATAATGTTAGCTCTTA silent|GGC>GGG|G|33 silent|GGC>GGT|G|33 SSU72 Suppressor of SUa7, gene 2 206.0 0 0 0 0 -0.3819650556427209 P53538 44.73596841540183 35.0 1.0 no 11525 chrXIV_229256r 29851 essential YNL222W 165 - GTACCAAATGAGTACACATT G|61|A G|61|D G|61|R G|61|S SSU72 Suppressor of SUa7, gene 2 206.0 0 0 0 0 -1.701235203846876 P53538 0.7476639747619629 0.7073860168457031 0.6749780178070068 0.8200939893722534 0.011479232460260393 0.042477983981370926 0.007171160075813531 0.07857486605644226 40.88263107935933 35.0 1.0 no 11526 chrXIV_229253 29852 essential YNL222W 159 + AAGCCTAATGTGTACTCATT P|55|A P|55|S P|55|R P|55|L SSU72 Suppressor of SUa7, gene 2 206.0 0 0 0 0 0.3903096062511112 P53538 0.8077099919319153 0.6561310291290283 0.6196330189704895 0.6663550138473511 0.010108302347362041 0.008569463156163692 0.007304561790078878 0.005165534093976021 44.30111410864311 35.0 1.0 no 11527 chrXIV_229374 29855 essential YNL222W 280 + TCAAAAAAGCACCTGAAAAA silent|CTC>CTG|L|94 silent|CTC>CTT|L|94 SSU72 Suppressor of SUa7, gene 2 206.0 0 0 0 0 -0.15627123502709567 P53538 32.783042265025465 30.0 1.0 no 11528 chrXIV_229455r 29856 essential YNL222W 364 - ATTCATCAAATCTTCACAAA M|127|I M|127|I L|126|F silent|TTG>TTA|L|126 SSU72 Suppressor of SUa7, gene 2 206.0 0 0 0 0 0.7241971276167551 P53538 1.0619800090789795 1.0619800090789795 0.8577359914779663 0.3990497887134552 0.3990497887134552 0.07277391105890274 0.5989000201225281 0.5989000201225281 1.69868004322052 35.56084407941199 25.0 1.0 no 11529 chrXIV_231744r 29858 essential YNL221C 1929 + ACTAAATTACCGGCATATAG T|644|S T|644|I 0 0 0 0 0.6198835779240389 P41812 0.9491789937019348 0.9472420215606691 0.7418349981307983 0.21023452281951904 39.85476163861023 35.0 0.0 no 11530 chrXIV_231754r 29860 essential YNL221C 1919 + CATCCATAACACTAAATTAC I|641|M silent|ATC>ATT|I|641 H|642|D H|642|Y 0 0 0 0 -0.03271698847519959 P41812 0.9598389863967896 0.9473130106925964 0.9489949941635132 0.0694984495639801 0.05700446665287018 0.00859785359352827 35.91854561736415 30.0 0.0 no 11531 chrXIV_231815 29861 essential YNL221C 1861 - CTTCCTATCCCACTTCGTCT R|626|S silent|AGG>AGA|R|626 R|626|T R|626|K 0 0 0 0 -1.8081595816256035 P41812 0.9087679982185364 0.932735025882721 0.955805003643036 0.19560398161411285 0.046007569879293435 0.8279873728752136 57.54001356195658 50.0 0.0 no 11532 chrXIV_231993 29864 essential YNL221C 1683 - AACGGTAGCAGCCAGAACCA silent|CCG>CCC|P|567 silent|CCG>CCA|P|567 0 0 0 0 -1.7050252439512144 P41812 52.39467310092277 55.00000000000001 0.0 no 11533 chrXIV_232016 29865 essential YNL221C 1660 - TAACACAACAATCCAATCCC silent|GTG>GTC|V|559 silent|GTG>GTA|V|559 V|559|L V|559|M 0 0 0 0 0.32848673849480714 P41812 0.9539830088615416 0.9587630033493042 1.0 0.3642728626728058 42.90067420538651 40.0 0.0 no 11534 chrXIV_232208 29866 essential YNL221C 1468 - GTCACATAATTCGTTAAAAA D|496|H D|496|N C|495|S C|495|Y 0 0 0 0 0.9587102129398624 P41812 0.9486550092697144 0.956179976463318 0.9421560168266296 0.9290120005607604 0.048894163221120834 0.4579883515834808 0.6253729462623596 0.12932559847831726 33.423319097547214 25.0 0.0 no 11535 chrXIV_232227 29867 essential YNL221C 1449 - ACGGCGTTTATTTCGTCTTG V|490|L V|490|I A|489|P A|489|T 0 0 0 0 -0.16826508172672516 P41812 0.9539830088615416 0.9574310183525084 0.9573720097541808 0.9523990154266356 0.090970978140831 0.7952479720115662 0.25815579295158386 0.5598135590553284 48.87777254937919 45.0 0.0 no 11536 chrXIV_232367r 29869 essential YNL221C 1306 + ATCATAATGCCCTACCACAG H|437|D H|437|Y 0 0 0 0 0.28392854547157753 P41812 0.9473130106925964 0.9489949941635132 0.35834747552871704 1.0 49.18270778092381 45.0 0.0 no 11537 chrXIV_232358 29870 essential YNL221C 1318 - AAACGTACACCTCTGTGGTA silent|ACG>ACC|T|445 silent|ACG>ACA|T|445 0 0 0 0 -1.4206509031189185 P41812 47.2965054259202 45.0 0.0 no 11538 chrXIV_232445r 29871 essential YNL221C 1228 + AGTCATTAGCATCGTGTTTA S|411|* S|411|L 0 0 0 0 0.4347562742288093 P41812 0.9298099875450134 0.014900567941367624 46.17635238031187 35.0 0.0 no 11539 chrXIV_232537r 29872 essential YNL221C 1136 + TAACATTCTTTTGCAACATA N|380|K silent|AAC>AAT|N|380 0 0 0 0 0.5006453427184892 P41812 0.9439849853515624 0.7799580693244934 37.606485821761396 25.0 0.0 no 11540 chrXIV_232564r 29873 essential YNL221C 1109 + ACACCCTTCAATTTATACTC H|371|Q silent|CAC>CAT|H|371 H|371|D H|371|Y 0 0 0 0 -1.154671508878438 P41812 0.9588389992713928 0.9473130106925964 0.9489949941635132 0.0 0.0 0.0 44.633079308033075 35.0 0.0 no 11541 chrXIV_232606r 29874 essential YNL221C 1067 + CGACGTATTTTGGGTACAAA D|357|E silent|GAC>GAT|D|357 0 0 0 0 0.3670473730042628 P41812 0.9532920122146606 1.0 41.82215657940032 40.0 0.0 no 11542 chrXIV_232707r 29875 essential YNL221C 966 + AACTTAAGGAAATATCGCGA N|323|K silent|AAC>AAT|N|323 0 0 0 0 -0.2369337023925195 P41812 0.9439849853515624 0.2671776711940765 37.5304579778911 35.0 0.0 no 11543 chrXIV_232721r 29876 essential YNL221C 952 + CAGCTGAAAGAGCAAACTTA A|319|G A|319|V 0 0 0 0 0.5044158415577945 P41812 0.9484469890594482 0.9504740238189696 0.18291586637496948 0.04041263461112976 39.773731798642814 40.0 0.0 no 11544 chrXIV_232739 29877 essential YNL221C 937 - AGCTGTTAACTTTCCTATAA A|319|P A|319|T 0 0 0 0 0.1274828457286849 P41812 0.9573720097541808 0.9523990154266356 0.06662479043006897 0.11082301288843156 42.251479517692644 30.0 0.0 no 11545 chrXIV_232777r 29878 essential YNL221C 896 + AGACAAAAGCAATGACAGTG D|300|E silent|GAC>GAT|D|300 0 0 0 0 -0.1542097449793141 P41812 0.9532920122146606 0.9300195574760436 37.26171887900245 40.0 0.0 no 11546 chrXIV_232815r 29879 essential YNL221C 858 + TGCATGGATTCAAGTTATAT C|287|W silent|TGC>TGT|C|287 0 0 0 0 -0.9380754898164878 P41812 0.9286419749259948 0.014801823534071444 40.48253433181566 30.0 0.0 no 11547 chrXIV_232948 29881 essential YNL221C 728 - ACCTTTTAGCATTCCAAATG R|249|T R|249|K R|249|S silent|AGG>AGA|R|249 0 0 0 0 -1.0666937151621283 P41812 0.932735025882721 0.955805003643036 0.9087679982185364 0.0 0.0 0.0 43.96603403405003 35.0 0.0 no 11548 chrXIV_232949 29882 essential YNL221C 727 - CCTTTTAGCATTCCAAATGT R|249|T R|249|K 0 0 0 0 -0.06961279253742401 P41812 0.932735025882721 0.955805003643036 0.0 0.0 45.96369167786236 35.0 0.0 no 11549 chrXIV_232949r 29883 essential YNL221C 724 + CCCACATTTGGAATGCTAAA H|243|D H|243|Y silent|ACC>ACG|T|242 silent|ACC>ACT|T|242 0 0 0 0 0.26228348614924474 P41812 0.9473130106925964 0.9489949941635132 0.0 0.0 44.459111270579854 40.0 0.0 no 11550 chrXIV_233150r 29886 essential YNL221C 523 + CATCATCTAACTGCCACGTA S|176|* S|176|L S|177|C S|177|F 0 1 0 0 -1.2682112498207194 P41812 0.9298099875450134 0.945252001285553 0.9294660091400146 0.35268786549568176 0.06950928270816803 0.05742562934756279 48.13382354282521 45.0 0.0 no 11551 chrXIV_233349 29888 essential YNL221C 327 - GCTCTATTGCGCATTCTTTT R|115|T R|115|K A|116|P A|116|T 0 0 0 0 0.3358033367309645 P41812 0.932735025882721 0.955805003643036 0.9573720097541808 0.9523990154266356 0.0 0.0 0.0 0.0 51.09982090197133 40.0 0.0 no 11552 chrXIV_233562r 29896 essential YNL221C 111 + GCCGCTTCATCAACAAAAAC silent|GCC>GCG|A|38 silent|GCC>GCT|A|38 A|38|G A|38|V 0 0 0 0 -0.3085463360363684 P41812 0.9484469890594482 0.9504740238189696 0.4238106906414032 0.2856730818748474 43.08089055204874 45.0 0.0 no 11553 chrXIV_234461 29902 exception YNL220W 48 + AAACTAGTTGATTTACTGGT L|18|V silent|CTA>TTA|L|18 ADE12 ADEnine requiring 433.0 0 0 0 0 -0.3728139116543098 P80210 0.9512209892272948 0.2948364317417145 39.02378283726552 30.0 1.0 no 11554 chrXIV_234510r 29905 exception YNL220W 100 - ATGCCCGGCATTGTTACCAC silent|GGG>GGC|G|39 silent|GGG>GGA|G|39 G|39|A G|39|E ADE12 ADEnine requiring 433.0 0 0 1 Series([], Name: modification, dtype: object) 0 -0.4392600888617048 P80210 0.9499930143356324 0.9438679814338684 0.01488066930323839 0.0035376022569835186 56.911905235577365 55.00000000000001 1.0 no 11555 chrXIV_234592 29908 exception YNL220W 179 + CCCAAACTGCCAAAACCTTT P|61|R P|61|L P|61|A P|61|S ADE12 ADEnine requiring 433.0 0 0 0 0 0.2915274913880983 P80210 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.06994914263486862 0.0402604267001152 0.2187998592853546 0.13229426741600034 47.72082810057765 45.0 1.0 no 11556 chrXIV_234593 29910 exception YNL220W 180 + CCAAACTGCCAAAACCTTTT P|61|R P|61|L N|62|K silent|AAC>AAT|N|62 ADE12 ADEnine requiring 433.0 0 0 0 0 0.20652883576724693 P80210 0.9432820081710817 0.9430609941482544 0.9439849853515624 0.06994914263486862 0.0402604267001152 1.0 44.70825214878874 40.0 1.0 no 11557 chrXIV_234663r 29912 exception YNL220W 253 - CTTCAAACCTTTAGCTTCCA L|90|F silent|TTG>TTA|L|90 ADE12 ADEnine requiring 433.0 0 1 0 0 0.5877056637507547 P80210 0.9587849974632264 0.010931631550192831 4.747000217437744 48.474446656840364 40.0 1.0 no 11558 chrXIV_234839 29916 exception YNL220W 426 + TCCACAAAGGCTTCTAGATC silent|TCC>TCG|S|143 silent|TCC>TCT|S|143 S|143|C S|143|F ADE12 ADEnine requiring 433.0 0 0 1 Series([], Name: modification, dtype: object) 0 -0.761155178045712 P80210 0.945252001285553 0.9294660091400146 0.0016315367538481949 0.0009921292075887322 46.799338175086746 45.0 1.0 no 11559 chrXIV_234893r 29917 exception YNL220W 483 - ACAAATTCCTCCCAGGCACC V|168|L V|168|I ADE12 ADEnine requiring 433.0 0 0 0 0 -0.3397859338657241 P80210 0.9539830088615416 0.9574310183525084 0.12777364253997806 0.07126748561859131 -0.8974000215530396 0.30720001459121704 55.72468470965907 55.00000000000001 1.0 no 11560 chrXIV_234894r 29918 exception YNL220W 484 - AACAAATTCCTCCCAGGCAC V|168|L V|168|I ADE12 ADEnine requiring 433.0 0 0 0 0 0.6231926009647129 P80210 0.9539830088615416 0.9574310183525084 0.12777364253997806 0.07126748561859131 -0.8974000215530396 0.30720001459121704 50.675806175675184 50.0 1.0 no 11561 chrXIV_234900r 29919 exception YNL220W 490 - TCTAGCAACAAATTCCTCCC R|170|T R|170|K A|169|P A|169|T ADE12 ADEnine requiring 433.0 0 0 0 0 0.19039692666769265 P80210 0.932735025882721 0.955805003643036 0.9573720097541808 0.9523990154266356 0.03932792693376541 1.0 0.21589741110801694 0.7117749452590942 4.511799812316895 0.8428000211715698 49.0198225593481 45.0 1.0 no 11562 chrXIV_234916 29920 exception YNL220W 503 + TGCTAGATATAAGAGATTAT A|169|G A|169|V ADE12 ADEnine requiring 433.0 0 0 0 0 0.729370378603638 P80210 0.9484469890594482 0.9504740238189696 0.29934635758399963 0.22480975091457367 1.0980000495910645 0.8985999822616577 34.89174140981561 25.0 1.0 no 11563 chrXIV_234984r 29921 exception YNL220W 574 - CTTCTTGTATTCAGCAAGCT K|197|N silent|AAG>AAA|K|197 ADE12 ADEnine requiring 433.0 0 0 0 0 0.3717430434628685 P80210 0.9355990290641784 0.04217817261815071 48.148007714991074 40.0 1.0 no 11564 chrXIV_235145 29923 exception YNL220W 732 + ACTTCTTCCAATACTGGTAT T|245|S T|245|I S|246|C S|246|F ADE12 ADEnine requiring 433.0 0 0 0 0 0.17375489222245138 P80210 0.9491789937019348 0.9472420215606691 0.945252001285553 0.9294660091400146 0.0 0.0 0.0 0.0 -0.4108000099658966 -1.7192000150680542 45.52171271423651 35.0 1.0 no 11565 chrXIV_235148 29924 exception YNL220W 735 + TCTTCCAATACTGGTATTGG S|246|C S|246|F S|247|C S|247|F ADE12 ADEnine requiring 433.0 0 0 0 0 -1.0325138488161922 P80210 0.945252001285553 0.9294660091400146 0.945252001285553 0.9294660091400146 0.0 0.0 0.0 0.0 -0.4108000099658966 -1.7192000150680542 45.644329668464536 40.0 1.0 no 11566 chrXIV_235233r 29926 exception YNL220W 823 - TTCACCAACTCTAGTTGTGT E|281|Q E|281|K G|280|A G|280|D ADE12 ADEnine requiring 433.0 0 0 0 0 -1.7144804143341834 P80210 0.956179976463318 0.9475290179252625 0.9499930143356324 0.9446240067481996 0.5911851525306702 0.884364664554596 0.0 0.0 48.49161776821376 40.0 1.0 no 11567 chrXIV_235235 29927 exception YNL220W 822 + TACACAACTAGAGTTGGTGA Y|275|* silent|TAC>TAT|Y|275 T|276|R T|276|I ADE12 ADEnine requiring 433.0 0 0 0 0 -0.20236323726240849 P80210 0.9476869702339172 0.9472420215606691 0.0046379021368920794 0.004765087738633156 42.572836073588974 40.0 1.0 no 11568 chrXIV_235264r 29929 exception YNL220W 854 - TTTCGTTCAATTGTTCCGTT E|291|Q E|291|K ADE12 ADEnine requiring 433.0 0 0 0 0 0.3284660304266516 P80210 0.956179976463318 0.9475290179252625 0.034284938126802444 0.14126162230968475 47.38750582542343 35.0 1.0 no 11569 chrXIV_235331 29931 exception YNL220W 918 + ACTGGTCGTAAGCGTCGTTG T|307|S T|307|I R|309|G R|309|C ADE12 ADEnine requiring 433.0 0 0 0 0 -0.6277839809719958 P80210 0.9491789937019348 0.9472420215606691 0.8994590044021606 0.8926740288734436 0.03806005790829658 0.0026813007425516844 0.002884628251194954 0.00039621893665753305 0.42820000648498535 0.12960000336170194 2.5302000045776367 2.2332000732421875 51.41695422731516 55.00000000000001 1.0 no 11570 chrXIV_235335 29932 exception YNL220W 922 + GTCGTAAGCGTCGTTGCGGT R|309|G R|309|C ADE12 ADEnine requiring 433.0 0 0 0 0 -1.0398020014804212 P80210 0.8994590044021606 0.8926740288734436 0.002884628251194954 0.00039621893665753305 2.5302000045776367 2.2332000732421875 56.3533723425183 60.0 1.0 no 11571 chrXIV_236462 29938 no_effect YNL219C 1182 - CCCGTACATACATTCACTAC silent|ACG>ACC|T|400 silent|ACG>ACA|T|400 G|401|R G|401|R ALG9 Asparagine-Linked Glycosylation 555.0 0 0 0 0 0.3254795126778124 P53868 0.941340982913971 0.941340982913971 0.0 0.0 47.651546688419565 45.0 0.0 no 11572 chrXIV_236562r 29943 no_effect YNL219C 1079 + CCAGGCAATGTCACGGATAG Q|361|E Q|361|* A|362|G A|362|V ALG9 Asparagine-Linked Glycosylation 555.0 0 0 0 0 -0.044934763381635816 P53868 0.9590039849281312 0.9484469890594482 0.9504740238189696 0.03985534608364105 0.0782604068517685 0.028155554085969925 49.65220653677756 55.00000000000001 0.0 no 11573 chrXIV_236585r 29945 no_effect YNL219C 1056 + TCAGTTTTATTAATTGTTGC S|353|* S|353|L ALG9 Asparagine-Linked Glycosylation 555.0 0 0 0 0 1.4446611598242658 P53868 0.9298099875450134 0.7286041975021362 38.863676073440274 25.0 0.0 no 11574 chrXIV_236721r 29946 no_effect YNL219C 920 + CACTCAACAACCTCACAAAG T|308|S T|308|I Q|309|E Q|309|* ALG9 Asparagine-Linked Glycosylation 555.0 0 0 0 0 0.9703482398844056 P53868 0.9491789937019348 0.9472420215606691 0.9590039849281312 0.16271091997623446 0.2944973111152649 1.0 41.331863152780436 45.0 0.0 no 11575 chrXIV_236813 29947 no_effect YNL219C 831 - GCTAAAACTAGCACAGGCAG A|284|P A|284|T ALG9 Asparagine-Linked Glycosylation 555.0 0 0 0 0 -0.4627356725548938 P53868 0.9573720097541808 0.9523990154266356 0.21035033464431765 0.4081108570098877 45.53058008049965 50.0 0.0 no 11576 chrXIV_236880r 29950 no_effect YNL219C 761 + ATCTGGCCCAAATATTTTCG S|255|C S|255|F silent|GGC>GGG|G|256 silent|GGC>GGT|G|256 ALG9 Asparagine-Linked Glycosylation 555.0 0 0 0 0 0.25452765253957643 P53868 0.945252001285553 0.9294660091400146 0.05798560753464699 0.06565700471401215 46.316961897371186 40.0 0.0 no 11577 chrXIV_236881r 29951 no_effect YNL219C 760 + AATCTGGCCCAAATATTTTC S|255|C S|255|F ALG9 Asparagine-Linked Glycosylation 555.0 0 0 0 0 0.036260847219904274 P53868 0.945252001285553 0.9294660091400146 0.05798560753464699 0.06565700471401215 43.75779989426894 35.0 0.0 no 11578 chrXIV_237111 29953 no_effect YNL219C 533 - GCCAGCCTAGTATACTAGCC W|184|S W|184|* W|184|C W|184|* ALG9 Asparagine-Linked Glycosylation 555.0 0 0 0 0 -1.9417037143609115 P53868 0.8858469724655151 0.8858469724655151 0.0 0.0 58.01701403951563 55.00000000000001 0.0 no 11579 chrXIV_237172r 29956 no_effect YNL219C 469 + CTCTACGCTATCTGTCCACT L|158|V silent|CTA>TTA|L|158 R|159|G R|159|C ALG9 Asparagine-Linked Glycosylation 555.0 0 0 0 0 0.17291821844017194 P53868 0.9512209892272948 0.8994590044021606 0.8926740288734436 0.4400433301925659 0.3537442982196808 0.050554130226373666 53.85539774504389 50.0 0.0 no 11580 chrXIV_237205 29957 no_effect YNL219C 439 - GGCACCTACATACAACAACA A|153|P A|153|T G|152|A G|152|D ALG9 Asparagine-Linked Glycosylation 555.0 0 0 0 0 -0.20694087039689044 P53868 0.9573720097541808 0.9523990154266356 0.9499930143356324 0.9446240067481996 0.03924111649394035 0.031876757740974426 0.1387888789176941 0.03996572270989418 45.508626760194495 45.0 0.0 no 11581 chrXIV_237173r 29958 no_effect YNL219C 468 + TCTCTACGCTATCTGTCCAC L|158|V silent|CTA>TTA|L|158 S|157|C S|157|F ALG9 Asparagine-Linked Glycosylation 555.0 0 0 0 0 0.1876844953495665 P53868 0.9512209892272948 0.945252001285553 0.9294660091400146 0.4400433301925659 0.1230574995279312 0.2625856697559357 53.17566381303027 50.0 0.0 no 11582 chrXIV_237211 29959 no_effect YNL219C 433 - TACATACAACAACATGGCAA V|151|L V|151|I L|149|F silent|TTG>TTA|L|149 ALG9 Asparagine-Linked Glycosylation 555.0 0 0 0 0 0.6816109786345612 P53868 0.9539830088615416 0.9574310183525084 0.9587849974632264 0.7747868895530701 0.6287072896957397 0.6938971281051636 38.542677931090346 35.0 0.0 no 11583 chrXIV_237218 29960 no_effect YNL219C 426 - AACAACATGGCAACGGCAGA L|148|F silent|TTG>TTA|L|148 M|147|I M|147|I ALG9 Asparagine-Linked Glycosylation 555.0 0 0 0 0 0.8424974901522386 P53868 0.9587849974632264 0.9553959965705872 0.9553959965705872 0.3763321042060852 0.05234115570783615 0.05234115570783615 45.70834427980554 50.0 0.0 no 11584 chrXIV_237374r 29966 no_effect YNL219C 267 + TTCATCACAAGAGCATGCTT F|90|L silent|TTC>TTT|F|90 I|91|M silent|ATC>ATT|I|91 ALG9 Asparagine-Linked Glycosylation 555.0 0 0 0 0 0.28398664858229844 P53868 0.9387490153312684 0.9598389863967896 0.03680897131562233 0.21013812720775604 46.372439094732506 40.0 0.0 no 11585 chrXIV_237403r 29967 no_effect YNL219C 238 + TTACTGACCTAGAAAGTCAT T|81|S T|81|I ALG9 Asparagine-Linked Glycosylation 555.0 0 0 0 0 -1.0497640661298309 P53868 0.9491789937019348 0.9472420215606691 0.3870395720005035 0.6068463921546936 41.0994812458124 35.0 0.0 no 11586 chrXIV_237472r 29969 no_effect YNL219C 169 + CCGAGTATTCTATTAGATCA silent|CCC>CCG|P|57 silent|CCC>CCT|P|57 ALG9 Asparagine-Linked Glycosylation 555.0 0 0 0 0 -0.2538953109615297 P53868 43.29770350934473 35.0 0.0 no 11587 chrXIV_237487 29970 no_effect YNL219C 157 - ATACTCGGGTGAATATTCCC E|58|D silent|GAG>GAA|E|58 E|58|Q E|58|K ALG9 Asparagine-Linked Glycosylation 555.0 0 0 0 0 -0.12273663820007402 P53868 0.94931298494339 0.956179976463318 0.9475290179252625 0.15649676322937012 0.13445404171943665 0.1735793650150299 48.377172139380896 45.0 0.0 no 11588 chrXIV_237524 29971 no_effect YNL219C 120 - CCACGTACCAATAAATTTAA R|46|P R|46|H G|47|R G|47|R ALG9 Asparagine-Linked Glycosylation 555.0 0 1 0 0 -0.04920960703874756 P53868 0.9099509716033936 0.9570810198783876 0.941340982913971 0.941340982913971 0.0 0.0 0.7299776077270508 0.7299776077270508 38.0150557718996 30.0 0.0 no 11589 chrXIV_237524r 29972 no_effect YNL219C 117 + CCATTAAATTTATTGGTACG P|40|R P|40|L ALG9 Asparagine-Linked Glycosylation 555.0 0 0 0 0 0.029009478398110463 P53868 0.9432820081710817 0.9430609941482544 0.0 0.0 37.890210633973034 30.0 0.0 no 11590 chrXIV_237622 29975 no_effect YNL219C 22 - TAACAACAGTAATAAACTAA L|13|F silent|TTG>TTA|L|13 silent|CTG>CTC|L|12 silent|CTG>CTA|L|12 ALG9 Asparagine-Linked Glycosylation 555.0 0 0 0 0 0.1462264147665842 P53868 0.9587849974632264 0.7162485122680664 28.313002853139487 20.0 0.0 no 11591 chrXIV_241721 29976 essential YNL216W 32 + AGCAGAATATGTTGATGCAT A|12|G A|12|V RAP1 Repressor/Activator site binding Protein 827.0 0 0 0 0 0.10966692872955107 P11938 42.355105384296614 35.0 1.0 no 11592 chrXIV_241775 29977 essential YNL216W 86 + TGCTGCAGTCACAGCGCCAT A|30|G A|30|V A|31|G A|31|V RAP1 Repressor/Activator site binding Protein 827.0 0 0 0 0 -1.0214229753116872 P11938 60.04914464994522 60.0 1.0 no 11593 chrXIV_241968 29982 essential YNL216W 279 + GCTAACATTGCTTCGACATC A|94|G A|94|V N|95|K silent|AAC>AAT|N|95 RAP1 Repressor/Activator site binding Protein 827.0 0 0 0 0 0.5499367789222329 P11938 46.49861253248282 45.0 1.0 no 11594 chrXIV_242078 29985 essential YNL216W 389 + ATTCTATCTTAATCGCGACG F|131|L silent|TTC>TTT|F|131 RAP1 Repressor/Activator site binding Protein 827.0 0 0 0 0 -0.5615658400684499 P11938 0.0 0.9818000197410583 42.83785784207214 40.0 1.0 no 11595 chrXIV_242181r 29987 essential YNL216W 495 - ACATTCTCTTTTGATTCTCT V|172|L V|172|I E|170|D silent|GAG>GAA|E|170 RAP1 Repressor/Activator site binding Protein 827.0 0 0 0 0 0.20691160123433608 P11938 0.6648662090301514 0.3995271921157837 1.9528000354766848 2.995199918746948 -0.13459999859333038 44.70625776268304 30.0 1.0 no 11596 chrXIV_242313r 29991 essential YNL216W 627 - ACTTCTCTAAAGTTATCGTA V|216|L V|216|I E|215|Q E|215|K RAP1 Repressor/Activator site binding Protein 827.0 0 0 0 0 -0.7342673059592132 P11938 0.4208138585090637 0.2401723265647888 0.4911867082118988 0.627198338508606 40.11709382371106 30.0 1.0 no 11597 chrXIV_242473r 29995 essential YNL216W 787 - GTCTACCATAACTTTTTCGC D|269|H D|269|N V|268|L V|268|I RAP1 Repressor/Activator site binding Protein 827.0 0 0 0 0 0.5482064565722496 P11938 0.2087073475122452 0.4815276563167572 0.5272889733314514 0.6721475124359131 46.69784497018941 40.0 1.0 no 11598 chrXIV_242534r 29996 essential YNL216W 848 - TGCTGCTTACATGTTGACGA S|289|T S|289|N S|288|T S|288|N RAP1 Repressor/Activator site binding Protein 827.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.7217661915898761 P11938 0.5019541382789612 0.4349838197231293 0.3655276894569397 0.3278057277202606 48.44925971303393 45.0 1.0 no 11599 chrXIV_242553 29998 essential YNL216W 864 + AGCACCGCATCAATCACAAG S|289|R silent|AGC>AGT|S|289 T|290|S T|290|I RAP1 Repressor/Activator site binding Protein 827.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.7874859140366316 P11938 0.4988243579864502 0.7661077976226807 0.19702713191509247 47.8575073788453 50.0 1.0 no 11600 chrXIV_242707 30002 essential YNL216W 1018 + ATGCATCTTTTCAAGCACAA A|341|G A|341|V S|342|C S|342|F RAP1 Repressor/Activator site binding Protein 827.0 0 1 0 0 0.8824123084809796 P11938 0.5184980034828186 0.3990284502506256 0.05635137856006622 0.06531847268342973 43.80618116402825 35.0 1.0 no 11601 chrXIV_242864 30004 essential YNL216W 1175 + CCATTATGTGCCTAACCACA H|393|D H|393|Y RAP1 Repressor/Activator site binding Protein 827.0 0 0 0 0 -0.3481981786953553 P11938 0.2260471284389496 0.03292873874306679 0.37541601061820973 -0.5687059760093689 50.783090804657256 45.0 1.0 no 11602 chrXIV_243142 30009 essential YNL216W 1453 + ATACACCCACTGCTATAGCG T|486|R T|486|I P|487|A P|487|S RAP1 Repressor/Activator site binding Protein 827.0 1 Series([], Name: modification, dtype: object) 0 0 0 -5.34670586141792 P11938 0.5071718096733093 0.18410994112491608 0.14908717572689054 0.07914628088474274 51.071020702871465 50.0 1.0 yes 11603 chrXIV_243148r 30010 essential YNL216W 1462 - ATTCCTCCTCGCTATAGCAG R|493|S silent|AGG>AGA|R|493 R|493|T R|493|K RAP1 Repressor/Activator site binding Protein 827.0 0 1 0 0 -1.655936710694664 P11938 0.10369873046875 0.19164493680000305 0.5763300657272339 54.591458299598344 50.0 1.0 no 11604 chrXIV_243195r 30013 essential YNL216W 1509 - GCAAAGTTGGGTTCACTCCC A|510|P A|510|T RAP1 Repressor/Activator site binding Protein 827.0 0 0 0 0 -3.783403884360797 P11938 0.22454011440277102 0.4531835317611694 54.891390734780884 55.00000000000001 1.0 yes 11605 chrXIV_243207r 30014 essential YNL216W 1521 - GTTCTGTAAGCTGCAAAGTT R|513|T R|513|K RAP1 Repressor/Activator site binding Protein 827.0 0 0 0 0 0.25001607622907585 P11938 0.10347823053598404 0.2599189579486847 0.630154013633728 0.154216006398201 45.58672796296816 40.0 1.0 no 11606 chrXIV_243221 30015 essential YNL216W 1532 + TTACAGAACCCAAAGCCGTA Y|512|* silent|TAC>TAT|Y|512 RAP1 Repressor/Activator site binding Protein 827.0 0 0 0 0 -0.9379904387695754 P11938 47.266238727629464 45.0 1.0 no 11607 chrXIV_243229r 30017 essential YNL216W 1543 - AATCGGTCCCCTACGGCTTT silent|CCG>CCC|P|520 silent|CCG>CCA|P|520 RAP1 Repressor/Activator site binding Protein 827.0 0 0 0 0 -0.4910590037004793 P11938 57.63321763801883 55.00000000000001 1.0 no 11608 chrXIV_243236r 30018 essential YNL216W 1550 - CTCGTGCAATCGGTCCCCTA R|523|P R|523|Q A|522|P A|522|T RAP1 Repressor/Activator site binding Protein 827.0 0 0 0 0 -4.282705974735078 P11938 0.1475069671869278 0.3093434572219849 0.3819963037967682 0.18957923352718356 -0.4284740090370178 0.09081199765205383 -0.20050199329853055 1.4606779813766482 59.195185895058565 60.0 1.0 yes 11609 chrXIV_243304 30020 essential YNL216W 1615 + ATGCTTGGAGAGATAGGTTT A|540|G A|540|V RAP1 Repressor/Activator site binding Protein 827.0 0 0 0 0 -3.3952295703417104 P11938 0.03471743687987328 0.01144183799624443 1.0488200187683103 1.3325239419937134 46.13408820558704 40.0 1.0 yes 11610 chrXIV_243523r 30029 essential YNL216W 1837 - AGCATTAGCGGACGCTGCAT A|619|P A|619|T RAP1 Repressor/Activator site binding Protein 827.0 0 0 0 0 -0.27319858911544503 P11938 0.25686556100845337 0.643669068813324 54.20560831821064 55.00000000000001 1.0 no 11611 chrXIV_247504 30031 no_effect YNL212W 43 + AGCTCATCACGATACCTTCT L|16|V L|16|F silent|CTC>CTG|L|16 silent|CTC>CTT|L|16 VID27 Vacuolar Import and Degradation 782.0 0 0 0 0 0.07231739269875065 P40157 0.3183470368385315 0.033280771225690835 50.91371677944159 45.0 1.0 no 11612 chrXIV_247557r 30033 no_effect YNL212W 99 - ATACATTCTAAAGCAGCTTT C|39|S C|39|Y VID27 Vacuolar Import and Degradation 782.0 0 1 0 0 0.7564744591483639 P40157 0.0 0.0 40.952201215182576 30.0 1.0 no 11613 chrXIV_247720r 30037 no_effect YNL212W 262 - TTCTTTCTTTTTAGACTGTG E|94|Q E|94|K K|92|N silent|AAG>AAA|K|92 VID27 Vacuolar Import and Degradation 782.0 0 1 0 0 1.338212995146619 P40157 0.18278737366199493 0.03977498039603233 0.4894908368587494 41.92123082421591 30.0 1.0 no 11614 chrXIV_247772 30038 no_effect YNL212W 311 + AATCATGTTTCACAAAACAT I|105|M silent|ATC>ATT|I|105 VID27 Vacuolar Import and Degradation 782.0 0 0 0 0 0.308884005339226 P40157 0.02863962203264236 34.94950811398752 25.0 1.0 no 11615 chrXIV_247873r 30040 no_effect YNL212W 415 - ATCAGAAAACGACACATCAG D|145|H D|145|N VID27 Vacuolar Import and Degradation 782.0 0 0 0 0 -0.5332727782153635 P40157 0.0650268942117691 0.19657453894615173 37.62658768033629 40.0 1.0 no 11616 chrXIV_247921 30041 no_effect YNL212W 460 + ACCGATGCCAATTCGAAGTA R|155|G R|155|* Y|154|* silent|TAC>TAT|Y|154 VID27 Vacuolar Import and Degradation 782.0 0 0 0 0 0.029508082971706037 P40157 0.04106990620493889 47.121443195035106 45.0 1.0 no 11617 chrXIV_247922r 30042 no_effect YNL212W 464 - TCCTTACTTCGAATTGGCAT R|161|T R|161|K R|161|S silent|AGG>AGA|R|161 VID27 Vacuolar Import and Degradation 782.0 0 1 0 0 -0.6008089789489046 P40157 0.011636951938271524 1.0 0.009335211478173731 47.5158503535892 40.0 1.0 no 11618 chrXIV_248142r 30044 no_effect YNL212W 684 - AAACAACAATATTCCCCTTC C|234|S C|234|Y C|233|S C|233|Y VID27 Vacuolar Import and Degradation 782.0 0 0 0 0 0.6009830801987142 P40157 0.4012170135974884 1.0 0.2592252790927887 0.4367728531360626 42.21033894305498 35.0 1.0 no 11619 chrXIV_248198 30045 no_effect YNL212W 737 + TCAAGAAAAATTTATTCTGC Q|247|E Q|247|* VID27 Vacuolar Import and Degradation 782.0 0 0 0 0 0.55875516884544 P40157 1.0 32.688671595413496 25.0 1.0 no 11620 chrXIV_248332r 30049 no_effect YNL212W 874 - GGCATCGGTAGCTAATTCAA A|298|P A|298|T D|297|H D|297|N VID27 Vacuolar Import and Degradation 782.0 0 0 0 0 -0.5161087404166487 P40157 0.06761077791452408 0.2883360683917999 0.5450820922851562 0.6390581727027893 47.605471479814405 45.0 1.0 no 11621 chrXIV_248488r 30052 no_effect YNL212W 1030 - TTTCTCCTTTTCAGGAACGT E|349|D silent|GAG>GAA|E|349 E|349|Q E|349|K VID27 Vacuolar Import and Degradation 782.0 0 0 0 0 0.3032539569605565 P40157 0.2067521959543228 0.2718404531478882 0.030238982290029526 48.68150186772671 40.0 1.0 no 11622 chrXIV_248683r 30053 no_effect YNL212W 1225 - CGCACGCCTAGGTTCTTCAA A|415|P A|415|T R|414|P R|414|H VID27 Vacuolar Import and Degradation 782.0 0 0 0 0 0.7258853753056482 P40157 0.2781372964382172 0.5635858178138733 0.2017560750246048 0.5414130091667175 54.48192019397664 55.00000000000001 1.0 no 11623 chrXIV_248694r 30055 no_effect YNL212W 1236 - CCTTTGGAAGTCGCACGCCT G|419|R G|419|S VID27 Vacuolar Import and Degradation 782.0 0 0 0 0 0.8138841439129588 P40157 0.2914901375770569 0.4816274344921112 57.2613449173212 60.0 1.0 no 11624 chrXIV_248722 30056 no_effect YNL212W 1261 + GTTCATTGACTGTCGCCTTT S|422|* S|422|L VID27 Vacuolar Import and Degradation 782.0 0 0 0 0 1.6652007417236532 P40157 0.10390721261501312 52.86762878788864 45.0 1.0 no 11625 chrXIV_248710r 30057 no_effect YNL212W 1252 - AGTCAATGAACTATTACCTT L|423|F silent|TTG>TTA|L|423 VID27 Vacuolar Import and Degradation 782.0 0 0 0 0 0.6910429266809763 P40157 0.0 40.12116511826781 30.0 1.0 no 11626 chrXIV_248873 30058 no_effect YNL212W 1412 + TCATAAGCCAATGTTGTATA H|472|D H|472|Y VID27 Vacuolar Import and Degradation 782.0 0 0 0 0 0.1433356744360786 P40157 0.561504602432251 0.6799110770225525 41.004707508008956 30.0 1.0 no 11627 chrXIV_248994 30059 no_effect YNL212W 1533 + GACAAGAATGTTGTTCAATA D|512|E silent|GAC>GAT|D|512 VID27 Vacuolar Import and Degradation 782.0 0 0 0 0 -0.4791503090484662 P40157 0.7744232416152954 36.36185607815929 30.0 1.0 no 11628 chrXIV_249045r 30060 no_effect YNL212W 1587 - ACGCCAACAATTGTTTGTTC G|535|A G|535|D V|536|L V|536|I VID27 Vacuolar Import and Degradation 782.0 0 1 0 0 0.5790969326225389 P40157 0.18918216228485107 0.0094033470377326 0.23809848725795746 1.0 45.44791851805036 40.0 1.0 no 11629 chrXIV_255414r 30062 essential YNL207W 64 - ACTTCTAGAACCTTGTTCAA S|28|T S|28|N R|27|T R|27|K RIO2 RIght Open reading frame 425.0 0 0 0 0 0.2611091677012893 P40160 0.9512869715690612 0.9536849856376648 0.932735025882721 0.955805003643036 0.006486217491328715 1.0 0.00826606247574091 1.0 43.66894507143462 35.0 1.0 no 11630 chrXIV_255455 30063 essential YNL207W 102 + CCCTTGATTCATCAAATCTC silent|CCC>CCG|P|35 silent|CCC>CCT|P|35 P|35|R P|35|L RIO2 RIght Open reading frame 425.0 0 0 0 0 0.607874881147819 P40160 0.9432820081710817 0.9430609941482544 0.033840741962194436 0.026348523795604702 45.75461982080873 40.0 1.0 no 11631 chrXIV_255455r 30065 essential YNL207W 105 - CCCGAGATTTGATGAATCAA silent|TCG>TCC|S|41 silent|TCG>TCA|S|41 G|42|R G|42|R RIO2 RIght Open reading frame 425.0 0 0 0 0 -1.3352716606673058 P40160 0.941340982913971 0.941340982913971 0.6710805892944336 0.6710805892944336 42.97186144000153 40.0 1.0 no 11632 chrXIV_255492r 30067 essential YNL207W 142 - ACTAATGGCTCGGTTTGTTC S|54|T S|54|N RIO2 RIght Open reading frame 425.0 0 1 0 0 0.3437424479171727 P40160 0.9512869715690612 0.9536849856376648 0.2793334722518921 0.2458002120256424 48.825866814663236 45.0 1.0 no 11633 chrXIV_255502r 30069 essential YNL207W 152 - TGGCCAAATCACTAATGGCT A|57|P A|57|T L|56|F silent|TTG>TTA|L|56 RIO2 RIght Open reading frame 425.0 0 1 0 0 0.05654523757760984 P40160 0.9573720097541808 0.9523990154266356 0.9587849974632264 0.05227144435048103 0.1925787627696991 0.008229224942624569 8.415200233459473 0.9915999770164491 47.5153884513303 45.0 1.0 no 11634 chrXIV_255507r 30070 essential YNL207W 157 - AAGCTTGGCCAAATCACTAA K|58|N silent|AAG>AAA|K|58 RIO2 RIght Open reading frame 425.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.6920469216774996 P40160 0.9355990290641784 0.005828696303069592 44.16899425781355 40.0 1.0 no 11635 chrXIV_255773 30074 essential YNL207W 420 + TATCTGAAGAAATCCAACCA L|142|V silent|CTG>TTG|L|142 RIO2 RIght Open reading frame 425.0 0 1 0 0 0.5854686590496601 P40160 0.9512209892272948 0.1100933402776718 0.9965999722480774 40.070392187312045 35.0 1.0 no 11636 chrXIV_255775 30076 essential YNL207W 422 + TCTGAAGAAATCCAACCAGG L|142|V silent|CTG>TTG|L|142 RIO2 RIght Open reading frame 425.0 0 1 0 0 0.10039881726017463 P40160 0.9512209892272948 0.1100933402776718 0.9965999722480774 42.787826231410406 45.0 1.0 no 11637 chrXIV_255786r 30078 essential YNL207W 436 - CATCCAGTTTGCCCCCTGGT W|151|C W|151|* W|151|S W|151|* RIO2 RIght Open reading frame 425.0 0 0 0 0 0.3791440201286346 P40160 0.8858469724655151 0.8858469724655151 0.0 0.0 2.3299999237060547 2.6487998962402344 65.12760493756389 60.0 1.0 no 11638 chrXIV_255898 30081 essential YNL207W 545 + CTCGCGTCATATAGTCGTTA S|183|W S|183|L R|184|G R|184|C RIO2 RIght Open reading frame 425.0 0 0 0 0 -0.3267284332756676 P40160 0.9288619756698608 0.9298099875450134 0.8994590044021606 0.8926740288734436 0.003945888951420784 0.017485836520791054 0.0 0.0 -1.4564000368118286 1.2389999628067017 48.887615175981466 45.0 1.0 no 11639 chrXIV_255971r 30084 essential YNL207W 621 - ATCAGATCACTATAAAGCTT silent|CTG>CTC|L|213 silent|CTG>CTA|L|213 RIO2 RIght Open reading frame 425.0 0 0 0 0 0.06053029379423164 P40160 38.95154982413368 30.0 1.0 no 11640 chrXIV_255972r 30085 essential YNL207W 622 - CATCAGATCACTATAAAGCT silent|CTG>CTC|L|213 silent|CTG>CTA|L|213 RIO2 RIght Open reading frame 425.0 0 0 0 0 0.8322942011617864 P40160 40.06722004462654 35.0 1.0 no 11641 chrXIV_256001 30086 essential YNL207W 648 + ATCGTTGATCTAGCAAATAG I|217|M silent|ATC>ATT|I|217 RIO2 RIght Open reading frame 425.0 0 0 0 0 0.6911700399347069 P40160 0.9598389863967896 0.0 39.25058384013181 35.0 1.0 no 11642 chrXIV_256226 30087 essential YNL207W 873 + TCATCAATGCTCGACACTGA S|292|* S|292|L S|293|* S|293|L RIO2 RIght Open reading frame 425.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.7217268894788929 P40160 0.9298099875450134 0.9298099875450134 0.09319999814033507 1.2269999980926514 46.357947696223896 45.0 1.0 no 11643 chrXIV_284428 30092 essential YNL189W 168 + AACTTTATTCCCCCAACTGA N|57|K silent|AAC>AAT|N|57 SRP1 Suppressor of Rna Polymerase I 542.0 0 0 0 0 0.5252006198099501 Q02821 0.9035819768905641 0.929660141468048 0.5013599991798401 -0.8410000205039978 49.37565270563459 40.0 1.0 no 11644 chrXIV_284440r 30093 essential YNL189W 183 - TCAGAATCAGCGCCATCAGT D|68|H D|68|N SRP1 Suppressor of Rna Polymerase I 542.0 0 1 0 0 0.8418890000171081 Q02821 0.974511981010437 0.9857460260391236 0.1145527884364128 0.5231269001960754 52.22190541736165 50.0 1.0 no 11645 chrXIV_284623r 30095 essential YNL189W 366 - GCTTGAATGACGACATCAAT A|129|P A|129|T SRP1 Suppressor of Rna Polymerase I 542.0 0 0 0 0 0.02913393483941698 Q02821 0.9204549789428712 0.913263976573944 0.10000921040773393 1.0 5.32882022857666 3.421380043029785 8.255960464477539 2.8126800060272217 41.49700948644266 40.0 1.0 no 11646 chrXIV_284685 30098 essential YNL189W 425 + CCAACCTGAAATGTTACAAT Q|143|E Q|143|* P|144|A P|144|S SRP1 Suppressor of Rna Polymerase I 542.0 0 0 0 0 -0.09641460174573332 Q02821 0.9453369975090028 0.9358810186386108 0.924157977104187 0.3966842293739319 0.5048796534538269 0.408272385597229 0.8531000018119812 1.8809599876403809 1.916659951210022 40.15292230046555 35.0 1.0 no 11647 chrXIV_284688 30100 essential YNL189W 428 + ACCTGAAATGTTACAATTGG P|144|R P|144|L P|144|A P|144|S SRP1 Suppressor of Rna Polymerase I 542.0 0 0 0 0 0.8433057273189744 Q02821 0.9130749702453612 0.9161570072174072 0.9358810186386108 0.924157977104187 0.3608983457088471 0.6335487365722656 0.5048796534538269 0.408272385597229 2.3681800365448 0.6673399806022644 1.8809599876403809 1.916659951210022 39.039799852864924 35.0 1.0 no 11648 chrXIV_284689r 30101 essential YNL189W 432 - GCCTCCAATTGTAACATTTC E|150|D silent|GAG>GAA|E|150 A|151|P A|151|T SRP1 Suppressor of Rna Polymerase I 542.0 0 0 0 0 -0.32133199581030625 Q02821 0.898002028465271 0.9183449745178224 0.9276970028877258 0.011361390352249146 0.0039770244620740405 0.02605031244456768 2.438499927520752 7.112843990325928 2.9756600856781006 47.070755163191784 40.0 1.0 no 11649 chrXIV_284742 30102 essential YNL189W 482 + TACATCTGCTCAAACAAAAG T|162|R T|162|I S|163|C S|163|F SRP1 Suppressor of Rna Polymerase I 542.0 0 0 0 0 0.36128798337751616 Q02821 0.7603049874305725 0.7647849917411804 0.7755309939384459 0.7607769966125488 0.0024097706191241737 0.002597359707579017 0.006574266590178013 0.07024934142827988 -0.1199200004339218 0.7116000056266785 0.9433599710464478 0.9045199751853944 -1.004699945449829 1.2834999561309814 1.5052000284194946 0.8675000071525574 35.993963616375936 35.0 1.0 no 11650 chrXIV_284791 30103 essential YNL189W 531 + TTCATTCAACTATTATATAC F|178|L silent|TTC>TTT|F|178 Q|180|E Q|180|* SRP1 Suppressor of Rna Polymerase I 542.0 0 0 0 0 -0.2868191584922645 Q02821 0.9225879907608032 0.941004991531372 0.3539018630981445 0.7584481835365295 0.4584200084209442 0.44780001044273376 33.42085537816314 20.0 1.0 no 11651 chrXIV_284837r 30106 essential YNL189W 580 - AACGTTACCTAAGGCCCAAA V|200|L V|200|I SRP1 Suppressor of Rna Polymerase I 542.0 0 0 0 0 0.3998171585536641 Q02821 0.8181790113449097 0.8371469974517822 0.012076789513230324 1.0 -0.8001800179481506 -1.1264599561691284 47.30548557133466 45.0 1.0 no 11652 chrXIV_284846r 30107 essential YNL189W 589 - ATCACCTGCAACGTTACCTA D|203|H D|203|N G|202|A G|202|D SRP1 Suppressor of Rna Polymerase I 542.0 0 0 0 0 -1.2526542293086729 Q02821 0.8704540133476257 0.8837040066719055 0.8107979893684387 0.8072739839553833 0.0017159000271931288 0.005543000064790249 0.013635775074362757 0.0036731865257024774 10.35282039642334 1.3876199722290041 2.054219961166382 13.772997856140135 50.20716607919775 45.0 1.0 no 11653 chrXIV_284936 30108 essential YNL189W 676 + CCAATAAACCATCTTTGATC silent|TCC>TCG|S|226 silent|TCC>TCT|S|226 SRP1 Suppressor of Rna Polymerase I 542.0 0 0 0 0 -0.23204982066624785 Q02821 40.686788037894985 35.0 1.0 no 11654 chrXIV_284969 30110 essential YNL189W 709 + GGACTTTATCCAATTTATGC T|238|S T|238|I SRP1 Suppressor of Rna Polymerase I 542.0 0 0 0 0 1.4089897874914226 Q02821 0.8267920017242432 0.7665320038795471 0.0092001399025321 0.014227097854018213 0.3939799964427948 2.966779947280884 43.29538103026425 35.0 1.0 no 11655 chrXIV_284971 30111 essential YNL189W 711 + ACTTTATCCAATTTATGCAG T|238|S T|238|I SRP1 Suppressor of Rna Polymerase I 542.0 0 0 0 0 0.8663269578118982 Q02821 0.8267920017242432 0.7665320038795471 0.0092001399025321 0.014227097854018213 0.3939799964427948 2.966779947280884 41.08832772237804 30.0 1.0 no 11656 chrXIV_285000 30112 essential YNL189W 740 + ACCACAACCAGATTGGTCAG P|248|R P|248|L P|248|A P|248|S SRP1 Suppressor of Rna Polymerase I 542.0 0 0 0 0 -0.8471374396284377 Q02821 0.8875849843025208 0.884443998336792 0.902917981147766 0.8975920081138611 0.0020960334222763772 0.004097618628293276 0.013629930093884468 0.006654198747128247 2.1683199405670166 2.2162799835205083 2.247339963912964 2.3085401058197017 49.34138314337491 50.0 1.0 no 11657 chrXIV_285001r 30113 essential YNL189W 744 - ACCACTGACCAATCTGGTTG silent|GTG>GTC|V|254 silent|GTG>GTA|V|254 V|255|L V|255|I SRP1 Suppressor of Rna Polymerase I 542.0 0 0 0 0 -0.2633858587215123 Q02821 0.8609409928321838 0.8787789940834045 0.03559715673327446 0.21225444972515106 0.8350399732589722 -0.4205799996852875 -0.3728399872779846 -1.2411799430847168 50.163981112090426 50.0 1.0 no 11658 chrXIV_285074 30114 essential YNL189W 814 + AAACTTTAGTTGATGCTTGT T|273|S T|273|I SRP1 Suppressor of Rna Polymerase I 542.0 0 0 0 0 0.8220953884701361 Q02821 0.8374050259590149 0.7832390069961548 0.0012045504990965128 0.3645961284637451 -0.10480000078678132 -1.8907599449157717 40.63534267306903 30.0 1.0 no 11659 chrXIV_285097 30115 essential YNL189W 837 + GCTATCTCTTATCTATCTGA A|280|G A|280|V I|281|M silent|ATC>ATT|I|281 SRP1 Suppressor of Rna Polymerase I 542.0 0 0 0 0 -0.2349372918180484 Q02821 0.8259620070457458 0.8084049820899963 0.8269870281219482 0.009238103404641151 0.0043469201773405075 0.007278082426637411 1.8707000017166135 3.5618000030517583 -0.06904000043869019 45.81602762728761 35.0 1.0 no 11660 chrXIV_285075 30116 essential YNL189W 815 + AACTTTAGTTGATGCTTGTT T|273|S T|273|I SRP1 Suppressor of Rna Polymerase I 542.0 0 0 0 0 1.535968988832032 Q02821 0.8374050259590149 0.7832390069961548 0.0012045504990965128 0.3645961284637451 -0.10480000078678132 -1.8907599449157717 42.38694880448338 30.0 1.0 no 11661 chrXIV_285204r 30118 essential YNL189W 947 - CAGCTCTTAAAGCAGGAGTC A|322|P A|322|T R|321|T R|321|K SRP1 Suppressor of Rna Polymerase I 542.0 0 0 0 0 -0.8936159335120325 Q02821 0.7630469799041748 0.7959740161895752 0.7759630084037781 0.7874879837036133 0.02190888486802578 1.0 0.0022617706563323736 0.013660349883139132 8.416686058044434 2.3627400398254395 1.2551599740982056 0.5121600031852722 3.339099884033203 2.314199924468994 47.98594145181613 50.0 1.0 no 11662 chrXIV_285211r 30121 essential YNL189W 954 - TTACCTACAGCTCTTAAAGC G|324|A G|324|D G|324|R G|324|S SRP1 Suppressor of Rna Polymerase I 542.0 0 0 0 0 -0.9755134076636264 Q02821 0.8131669759750366 0.7732639908790588 0.7471280097961426 0.8258860111236572 0.009062109515070915 0.004374956712126732 0.02143213152885437 0.005737178027629852 0.0026199999265372753 11.482084274291992 15.863304138183596 1.8692599534988403 44.96630045937047 40.0 1.0 no 11663 chrXIV_285349 30124 essential YNL189W 1089 + ACCATTTCCAATATTACGGC silent|ACC>ACG|T|364 silent|ACC>ACT|T|364 T|364|S T|364|I SRP1 Suppressor of Rna Polymerase I 542.0 0 0 0 0 0.22339777270281647 Q02821 0.8396909832954407 0.7877600193023682 0.01536011043936014 0.13306932151317594 0.686959981918335 -1.3606799840927124 46.686064294360726 40.0 1.0 no 11664 chrXIV_285414 30125 essential YNL189W 1154 + TCCTCCATTAGTTAAACTTT P|386|R P|386|L P|386|A P|386|S SRP1 Suppressor of Rna Polymerase I 542.0 0 0 0 0 0.6597361994256354 Q02821 0.7727190256118774 0.7627840042114258 0.7883319854736328 0.7863439917564392 0.08558209985494614 0.04862868413329125 0.19499686360359192 0.1218581274151802 2.82997989654541 2.958859920501709 3.2938001155853267 3.482759952545166 43.758154762971174 30.0 1.0 no 11665 chrXIV_285452 30126 essential YNL189W 1192 + AAACTAAAAAAGAAGCTTGT T|399|S T|399|I SRP1 Suppressor of Rna Polymerase I 542.0 0 1 0 0 -0.6524385249831159 Q02821 0.833154022693634 0.7722949981689453 0.318350613117218 0.7232227325439453 1.7892600297927856 -1.914139986038208 30.42817948438534 25.0 1.0 no 11666 chrXIV_285418r 30127 essential YNL189W 1161 - ACTTCCAAAAGTTTAACTAA V|394|L V|394|I E|393|Q E|393|K SRP1 Suppressor of Rna Polymerase I 542.0 0 1 0 0 0.6129308538043057 Q02821 0.8658679723739624 0.8770729899406433 0.910988986492157 0.8820919990539551 0.2946214079856873 0.18263979256153107 1.0 0.7295907735824585 0.22105999290943146 -0.6237000226974487 -0.3674600124359131 -0.8335999846458435 -1.0831400156021118 -0.6898000240325928 35.321349176669514 25.0 1.0 no 11667 chrXIV_285453 30128 essential YNL189W 1193 + AACTAAAAAAGAAGCTTGTT T|399|S T|399|I SRP1 Suppressor of Rna Polymerase I 542.0 0 1 0 0 0.21496909690620888 Q02821 0.833154022693634 0.7722949981689453 0.318350613117218 0.7232227325439453 1.7892600297927856 -1.914139986038208 31.661274790666933 25.0 1.0 no 11668 chrXIV_285475 30129 essential YNL189W 1215 + GCTATTTCCAATGCCTCTTC A|406|G A|406|V SRP1 Suppressor of Rna Polymerase I 542.0 0 0 0 0 0.2399414666349091 Q02821 0.8358839750289917 0.8167830109596252 0.052078191190958016 0.02584715932607651 1.7201999425888062 2.4810199737548833 52.81157337993932 45.0 1.0 no 11669 chrXIV_286382 30131 essential YNL188W 74 + ATTCCACAAACTAAATGAGC F|26|L silent|TTC>TTT|F|26 H|27|D H|27|Y KAR1 KARyogamy 433.0 0 0 0 0 0.04347070948645082 P11927 0.9387490153312684 0.9473130106925964 0.9489949941635132 38.46772978853864 35.0 1.0 no 11670 chrXIV_286422r 30132 essential YNL188W 117 - ACAATTGAATCACGGTCTTC V|46|L V|46|I KAR1 KARyogamy 433.0 0 0 0 0 -0.06556087824653972 P11927 0.9539830088615416 0.9574310183525084 0.0 0.0 42.39419870653353 40.0 1.0 no 11671 chrXIV_286430r 30133 essential YNL188W 125 - TACTTGAAACAATTGAATCA S|48|T S|48|N KAR1 KARyogamy 433.0 0 0 0 0 1.2999435436695808 P11927 0.9512869715690612 0.9536849856376648 0.10215654224157332 1.0 32.92219936519683 25.0 1.0 no 11672 chrXIV_286681r 30136 essential YNL188W 376 - TTCGTCCGATATGTACTCTT E|132|Q E|132|K D|131|H D|131|N KAR1 KARyogamy 433.0 0 1 0 0 -0.09583098415351893 P11927 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.1115156188607216 0.11436375230550765 0.1963982582092285 0.4909579753875733 48.233419215486485 40.0 1.0 no 11673 chrXIV_286930r 30139 essential YNL188W 625 - ATTCAAATACGGCAGCGGTA L|214|F silent|TTG>TTA|L|214 KAR1 KARyogamy 433.0 0 1 0 0 0.7924006989973007 P11927 0.9587849974632264 0.06751526892185211 46.38793089595089 45.0 1.0 no 11674 chrXIV_286974r 30141 essential YNL188W 669 - TCTTCTTTTCTCTGTAATGT E|230|Q E|230|K E|229|Q E|229|K KAR1 KARyogamy 433.0 0 1 0 0 0.6062175346247642 P11927 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.3837057054042816 0.3284790813922882 0.4719721972942352 0.9493264555931092 44.4217182419967 30.0 1.0 no 11675 chrXIV_286975r 30142 essential YNL188W 670 - TTCTTCTTTTCTCTGTAATG E|230|Q E|230|K E|229|Q E|229|K KAR1 KARyogamy 433.0 0 1 0 0 0.7373636698360937 P11927 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.3837057054042816 0.3284790813922882 0.4719721972942352 0.9493264555931092 41.9593881138897 30.0 1.0 no 11676 chrXIV_287192 30143 essential YNL188W 884 + AACAAAATCGTATGTTTCTT T|296|R T|296|I KAR1 KARyogamy 433.0 0 1 0 0 -0.1055702878946011 P11927 0.9476869702339172 0.9472420215606691 0.5604236721992493 0.21721787750720975 35.7468953941447 25.0 1.0 no 11677 chrXIV_287266r 30144 essential YNL188W 961 - TTCTTCTTTCTCCTTATTGT E|327|Q E|327|K E|326|Q E|326|K KAR1 KARyogamy 433.0 0 0 0 0 -0.31038288241281464 P11927 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.4283474385738373 0.5630501508712769 0.5136797428131104 0.7437673211097717 48.16607818232456 30.0 1.0 no 11678 chrXIV_296402 30145 essential YNL182C 1206 - TTTCCACGTTCGAGTCTGTA G|408|A G|408|E G|408|R G|408|R IPI3 Involved in Processing ITS2 555.0 0 0 0 0 0.12928410963705828 P53877 0.9499930143356324 0.9438679814338684 0.941340982913971 0.941340982913971 0.7321705222129822 1.0 0.5078052282333374 0.5078052282333374 51.30215084244424 45.0 0.0 no 11679 chrXIV_296460 30148 essential YNL182C 1148 - CCTGTGATGTAGTTAAAGTT Q|389|H silent|CAG>CAA|Q|389 IPI3 Involved in Processing ITS2 555.0 0 1 0 0 -0.3653529539916444 P53877 0.9570760130882264 0.1378958225250244 42.6044647027104 35.0 0.0 no 11680 chrXIV_296565r 30149 essential YNL182C 1040 + GTCATGCCTAGAAATATCAA S|348|* S|348|L C|349|W silent|TGC>TGT|C|349 IPI3 Involved in Processing ITS2 555.0 0 0 0 0 -0.8518960038214277 P53877 0.9298099875450134 0.9286419749259948 0.0809415951371193 0.07145892083644867 41.344924700337906 35.0 0.0 no 11681 chrXIV_296660r 30150 essential YNL182C 945 + CAACGTAACTCACTAACTGG R|317|G R|317|C IPI3 Involved in Processing ITS2 555.0 0 0 0 0 -0.7347280981557587 P53877 0.8994590044021606 0.8926740288734436 0.3039258420467377 0.04414954781532288 40.87449704566279 45.0 0.0 no 11682 chrXIV_296663r 30151 essential YNL182C 942 + GTGCAACGTAACTCACTAAC Q|316|E Q|316|* R|317|G R|317|C IPI3 Involved in Processing ITS2 555.0 0 0 0 0 -0.50407801839542 P53877 0.9590039849281312 0.8994590044021606 0.8926740288734436 1.0 0.3039258420467377 0.04414954781532288 42.617052477888926 45.0 0.0 no 11683 chrXIV_296939r 30158 essential YNL182C 666 + TGCTATGATTTGAGTTTAAT C|223|W silent|TGC>TGT|C|223 IPI3 Involved in Processing ITS2 555.0 0 0 0 0 -0.08060170411365189 P53877 0.9286419749259948 0.0 37.97154494644673 25.0 0.0 no 11684 chrXIV_296947 30159 essential YNL182C 661 - ACTCAAATCATAGCATCTAA L|226|F silent|TTG>TTA|L|226 S|227|T S|227|N IPI3 Involved in Processing ITS2 555.0 0 0 0 0 -0.3651111832516086 P53877 0.9587849974632264 0.9512869715690612 0.9536849856376648 0.167183056473732 0.110011987388134 1.0 38.36048584762705 30.0 0.0 no 11685 chrXIV_297203 30161 essential YNL182C 405 - ATACTTTGGTAATGAGCCAT S|141|T S|141|N IPI3 Involved in Processing ITS2 555.0 0 0 0 0 -0.2421336351418953 P53877 0.9512869715690612 0.9536849856376648 0.11324234306812285 0.05323963612318039 44.363216828281104 35.0 0.0 no 11686 chrXIV_297189 30162 essential YNL182C 419 - ACTTAATCTTGGTGATACTT K|146|N silent|AAG>AAA|K|146 IPI3 Involved in Processing ITS2 555.0 0 0 0 0 0.391753459168352 P53877 0.9355990290641784 0.07586633414030075 40.723026306929 30.0 0.0 no 11687 chrXIV_297258r 30164 essential YNL182C 347 + ATCGGGTAAATTGTACATAT S|117|W S|117|L IPI3 Involved in Processing ITS2 555.0 0 0 0 0 -0.43580046741891215 P53877 0.9288619756698608 0.9298099875450134 0.0044552027247846135 0.02152685821056366 38.80335656946596 30.0 0.0 no 11688 chrXIV_297265 30165 essential YNL182C 343 - GTACAATTTACCCGATTCGG L|120|F silent|TTG>TTA|L|120 IPI3 Involved in Processing ITS2 555.0 0 0 0 0 0.25988229677228225 P53877 0.9587849974632264 0.024335132911801338 46.63974179393985 45.0 0.0 no 11689 chrXIV_297290r 30167 essential YNL182C 315 + AATCTTCCGTACCTTTTACT L|107|V L|107|F P|108|A P|108|S IPI3 Involved in Processing ITS2 555.0 0 0 0 0 0.6298977193940071 P53877 0.9512209892272948 0.9587849974632264 0.9562489986419678 0.9498909711837769 0.08178301155567169 0.04662952944636345 0.0 0.0 47.34018575859182 35.0 0.0 no 11690 chrXIV_297372 30168 essential YNL182C 236 - CAACTACTTCCAGACATTTT V|85|L V|85|I V|84|L V|84|I IPI3 Involved in Processing ITS2 555.0 0 0 0 0 -0.6904654590063382 P53877 0.9539830088615416 0.9574310183525084 0.9539830088615416 0.9574310183525084 0.04066624864935875 0.21284814178943634 0.09459832310676576 0.43322497606277466 43.22695540529787 35.0 0.0 no 11691 chrXIV_297443r 30170 essential YNL182C 162 + ATCAATGTCTACAATCTGTC I|55|M silent|ATC>ATT|I|55 IPI3 Involved in Processing ITS2 555.0 0 0 0 0 -0.479352008110599 P53877 0.9598389863967896 0.0 41.13858194552989 35.0 0.0 no 11692 chrXIV_297517 30171 essential YNL182C 91 - ACAGCTATTTCTTGATTGAG C|37|S C|37|Y S|36|T S|36|N IPI3 Involved in Processing ITS2 555.0 0 0 0 0 0.6261250683671771 P53877 0.9421560168266296 0.9290120005607604 0.9512869715690612 0.9536849856376648 0.5394909381866455 0.2957183122634888 0.053246252238750465 0.027043264359235764 42.158560927977476 35.0 0.0 no 11693 chrXIV_298416r 30174 essential YNL181W 84 - GCACCAGTCGCTAGCACATA G|34|A G|34|D A|35|P A|35|T PBR1 Potentiates Bioactive compound Response 407.0 0 0 0 0 0.3946876910280016 P53878 0.9499930143356324 0.9446240067481996 0.9573720097541808 0.9523990154266356 0.5114486217498779 0.20488975942134854 0.0699232965707779 0.12889181077480316 55.77617842565871 55.00000000000001 1.0 no 11694 chrXIV_298437 30176 essential YNL181W 102 + GCCATTAAATATTGGTCGAG silent|GCC>GCG|A|35 silent|GCC>GCT|A|35 A|35|G A|35|V PBR1 Potentiates Bioactive compound Response 407.0 0 0 0 0 0.7627718382440578 P53878 0.9484469890594482 0.9504740238189696 0.1133955642580986 0.4467493295669556 42.89113256587235 40.0 1.0 no 11695 chrXIV_298461r 30178 essential YNL181W 129 - TTTCTTTCCCATGTATTTGA R|49|T R|49|K PBR1 Potentiates Bioactive compound Response 407.0 0 0 0 0 0.21881304500213145 P53878 0.932735025882721 0.955805003643036 0.006120257079601289 0.13384400308132172 46.80644769306456 30.0 1.0 no 11696 chrXIV_298540r 30184 essential YNL181W 208 - CTCTGCCATTTTATAAGCCA E|76|Q E|76|K A|75|P A|75|T PBR1 Potentiates Bioactive compound Response 407.0 0 1 0 0 -0.4603751760502679 P53878 0.956179976463318 0.9475290179252625 0.9573720097541808 0.9523990154266356 0.5969271659851074 0.9286643266677856 0.011293869465589523 0.007839996367692947 49.57086040993488 40.0 1.0 no 11697 chrXIV_298570 30185 essential YNL181W 235 + CACAATTAATCATCTTGACT Q|80|E Q|80|* PBR1 Potentiates Bioactive compound Response 407.0 0 0 0 0 0.2564715391223413 P53878 0.9590039849281312 0.016949482262134552 37.97530663615242 30.0 1.0 no 11698 chrXIV_298571 30186 essential YNL181W 236 + ACAATTAATCATCTTGACTA Q|80|E Q|80|* PBR1 Potentiates Bioactive compound Response 407.0 0 0 0 0 0.5465304760122162 P53878 0.9590039849281312 0.016949482262134552 36.081843035375975 25.0 1.0 no 11699 chrXIV_298696 30187 essential YNL181W 361 + TTCGTAAGTTTGCCACAAGT R|122|G R|122|C PBR1 Potentiates Bioactive compound Response 407.0 0 0 0 0 0.6715022655637002 P53878 0.8994590044021606 0.8926740288734436 0.0 0.0 46.86268110332588 40.0 1.0 no 11700 chrXIV_298731r 30188 essential YNL181W 399 - ACGCCATCTAATCTTCTAGG G|139|A G|139|D V|140|L V|140|I PBR1 Potentiates Bioactive compound Response 407.0 0 0 0 0 -2.7113171702900374 P53878 0.9499930143356324 0.9446240067481996 0.9539830088615416 0.9574310183525084 1.0 0.15958374738693235 0.04281233251094818 0.8413421511650085 48.171325350306695 45.0 1.0 yes 11701 chrXIV_298893r 30192 essential YNL181W 561 - GGCGGTTGAGCCTTGAAACT silent|CCG>CCC|P|193 silent|CCG>CCA|P|193 PBR1 Potentiates Bioactive compound Response 407.0 0 0 0 0 -0.06386620672034812 P53878 52.52838789722114 55.00000000000001 1.0 no 11702 chrXIV_298945r 30195 essential YNL181W 613 - ACCAACAACTTGTAACCAGC G|211|R G|211|S G|211|A G|211|D PBR1 Potentiates Bioactive compound Response 407.0 0 0 0 0 -1.1878831706216575 P53878 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0036273128353059288 0.02490508183836937 0.2382521778345108 0.004754558205604553 45.74062961434879 45.0 1.0 no 11703 chrXIV_299030 30197 essential YNL181W 695 + CGCAAGCAGCAAGCTACAAT A|233|G A|233|V S|234|R silent|AGC>AGT|S|234 PBR1 Potentiates Bioactive compound Response 407.0 0 0 0 0 0.3555276367977244 P53878 0.9484469890594482 0.9504740238189696 0.9417110085487366 1.0 0.016961179673671722 0.4708046019077301 47.40667296694727 50.0 1.0 no 11704 chrXIV_299102r 30198 essential YNL181W 770 - TTTCAGCGCCATTCGTCTTT E|263|Q E|263|K A|262|P A|262|T PBR1 Potentiates Bioactive compound Response 407.0 0 0 0 0 0.9029878186077224 P53878 0.956179976463318 0.9475290179252625 0.9573720097541808 0.9523990154266356 0.03693855926394463 0.17373394966125488 0.4355790913105011 0.5398257970809937 54.1376309869263 45.0 1.0 no 11705 chrXIV_299184 30202 essential YNL181W 849 + CTACGCCGCGTCATTAGTAA R|285|G R|285|C silent|CGC>CGG|R|285 silent|CGC>CGT|R|285 PBR1 Potentiates Bioactive compound Response 407.0 0 0 0 0 0.8583876869712295 P53878 0.8994590044021606 0.8926740288734436 0.01678571291267872 0.002449421212077141 50.32867724422408 50.0 1.0 no 11706 chrXIV_299189r 30204 essential YNL181W 857 - CCGAACCATTACTAATGACG silent|TCG>TCC|S|292 silent|TCG>TCA|S|292 G|291|A G|291|D PBR1 Potentiates Bioactive compound Response 407.0 0 0 0 0 -0.12671874623228327 P53878 0.9499930143356324 0.9446240067481996 0.0 0.0 42.68994324564022 45.0 1.0 no 11707 chrXIV_299239 30206 essential YNL181W 904 + TTCTGTTGTACCCCATATTG L|303|V silent|CTG>TTG|L|303 PBR1 Potentiates Bioactive compound Response 407.0 0 0 0 0 0.20627967171567665 P53878 0.9512209892272948 0.8196788430213928 50.04544288626045 40.0 1.0 no 11708 chrXIV_298728 30207 essential YNL181W 393 + TCGCCACCTAGAAGATTAGA P|133|A P|133|S S|132|W S|132|L PBR1 Potentiates Bioactive compound Response 407.0 0 0 0 0 -0.08854189454092742 P53878 0.9562489986419678 0.9498909711837769 0.9288619756698608 0.9298099875450134 0.030096458271145817 0.029883945360779762 0.13936270773410794 0.580080509185791 47.65860811411756 45.0 1.0 no 11709 chrXIV_302756r 30208 essential YNL178W 79 - ACCTTCTTCAGCTAATTCTC G|33|R G|33|S G|33|A G|33|D RPS3 Ribosomal Protein of the Small subunit 240.0 0 0 0 0 -3.3316967509046167 P05750 0.03373156487941742 0.025638019666075703 0.01806342601776123 0.005926465149968863 1.6830400228500366 2.648240089416504 2.017339944839477 2.825040102005005 6.915180206298827 5.750720024108888 5.547760009765625 4.3846402168273935 48.717263618755 40.0 1.0 yes 11710 chrXIV_302874 30210 essential YNL178W 194 + AATCAACGAATTAACTTTGT I|66|M silent|ATC>ATT|I|66 N|67|K silent|AAC>AAT|N|67 RPS3 Ribosomal Protein of the Small subunit 240.0 0 1 0 0 0.18622205451266616 P05750 0.016511732712388042 0.41439443826675415 -0.8829600214958191 -0.6090999841690063 -0.8874599933624268 -0.674340009689331 -0.4334999918937683 34.36127076821089 25.0 1.0 no 11711 chrXIV_303095r 30216 essential YNL178W 418 - TCTGGCAGCTCTTAGTTTAC R|146|T R|146|K A|145|P A|145|T RPS3 Ribosomal Protein of the Small subunit 240.0 0 1 0 0 -0.5480718742691049 P05750 0.0 0.0 0.023908602073788643 0.018583284690976143 0.15826000273227692 0.011380000039935112 2.2543399333953857 0.4964199960231781 0.0878399983048439 -0.037480000406503684 -1.0805599689483645 0.18916000425815585 0.30573999881744385 0.3259100019931793 1.1107100248336792 0.5156300067901611 51.11170874551448 45.0 1.0 no 11712 chrXIV_310672r 30221 essential YNL172W 39 - TCGCCATTGTGAGTTTCCCT G|19|A G|19|D E|20|Q E|20|K 0 0 0 0 -1.5622374221128683 P53886 0.9499930143356324 0.9446240067481996 0.956179976463318 0.9475290179252625 57.8218072598458 50.0 1.0 no 11713 chrXIV_310681 30222 essential YNL172W 45 + ACTCACAATGGCGAATATAC H|17|D H|17|Y T|16|S T|16|I 0 0 0 0 -0.0533610600980627 P53886 0.9473130106925964 0.9489949941635132 0.9491789937019348 0.9472420215606691 40.61583621276049 40.0 1.0 no 11714 chrXIV_310971r 30224 essential YNL172W 338 - ACCAGAATGCATTACCTATC W|119|S W|119|* W|119|C W|119|* 0 0 0 0 -0.5534565124153512 P53886 0.8858469724655151 0.8858469724655151 0.010584208182990551 0.007356122136116028 45.74028990784052 40.0 1.0 no 11715 chrXIV_311023 30225 essential YNL172W 387 + ACTTCAGCGTCCTTCATGGA T|130|S T|130|I S|131|* S|131|L 0 0 0 0 -0.15055224061313185 P53886 0.9491789937019348 0.9472420215606691 0.9298099875450134 0.7466474771499634 0.19500891864299771 0.32167065143585205 54.58988808936375 50.0 1.0 no 11716 chrXIV_311033r 30227 essential YNL172W 400 - ATCGTAGCCACCATCCATGA D|140|H D|140|N 0 0 0 0 -0.6812264113281564 P53886 0.9486550092697144 0.956179976463318 54.77776053284424 50.0 1.0 no 11717 chrXIV_311091 30228 essential YNL172W 455 + CATCACTTTGACGGATCCGA I|153|M silent|ATC>ATT|I|153 T|154|S T|154|I 0 0 0 0 0.3787280776954666 P53886 0.9598389863967896 0.9491789937019348 0.9472420215606691 0.0 0.0 0.0 49.032924975810715 50.0 1.0 no 11718 chrXIV_311107r 30230 essential YNL172W 474 - ATCAAGCCGAAAGGCGCCAT L|164|F silent|TTG>TTA|L|164 G|163|A G|163|D 0 0 0 0 -4.079085015560762 P53886 0.9587849974632264 0.9499930143356324 0.9446240067481996 0.7784373760223389 0.0 0.0 52.00603270944936 55.00000000000001 1.0 yes 11719 chrXIV_311144r 30231 essential YNL172W 511 - GCTATTTATACCGCCTTTAA S|177|T S|177|N 0 0 0 0 -0.10695489458743368 P53886 0.9512869715690612 0.9536849856376648 0.7313157320022583 0.7694962620735168 46.706308926053744 35.0 1.0 no 11720 chrXIV_311298 30235 essential YNL172W 662 + ATCATCAGATCAGTCACGGA S|222|* S|222|L S|223|* S|223|L 0 1 0 0 -0.4674973209251322 P53886 0.9298099875450134 0.9298099875450134 0.07913615554571153 0.0451526939868927 47.655601335485365 45.0 1.0 no 11721 chrXIV_311294 30236 essential YNL172W 658 + TTCTATCATCAGATCAGTCA L|221|V silent|CTA>TTA|L|221 S|222|* S|222|L 0 1 0 0 -0.3941980095117236 P53886 0.9512209892272948 0.9298099875450134 0.04570075124502182 0.07913615554571153 44.78986071520074 35.0 1.0 no 11722 chrXIV_311337 30238 essential YNL172W 701 + CTCGACCAAAAAAACAGGTT S|235|W S|235|L T|236|S T|236|I 0 0 0 0 -1.3032417503285387 P53886 0.9288619756698608 0.9298099875450134 0.9491789937019348 0.9472420215606691 0.028696423396468163 0.38850077986717213 0.8097023963928223 0.1885214000940323 38.90667416945331 40.0 1.0 no 11723 chrXIV_311491 30244 essential YNL172W 855 + GGCAATGTTGGCAACGCTTC silent|GGC>GGG|G|286 silent|GGC>GGT|G|286 0 0 0 0 0.6264161435423428 P53886 51.81861183479964 55.00000000000001 1.0 no 11724 chrXIV_311562 30245 essential YNL172W 926 + ATCTGCGACCCTAGATAGAA S|310|C S|310|F A|311|G A|311|V 1 Series([], Name: modification, dtype: object) 0 0 0 0.9485277863626741 P53886 0.945252001285553 0.9294660091400146 0.9484469890594482 0.9504740238189696 0.0 0.0 0.09237565845251083 0.03913521021604538 47.80260736702678 45.0 1.0 no 11725 chrXIV_311602 30249 essential YNL172W 966 + ACCAATAGAGCTGCACCTTC silent|ACC>ACG|T|323 silent|ACC>ACT|T|323 T|323|S T|323|I 0 0 0 0 0.11192231850885734 P53886 0.9491789937019348 0.9472420215606691 1.0 0.011083580553531648 51.80321180466626 50.0 1.0 no 11726 chrXIV_311718 30251 essential YNL172W 1082 + CCAAACAGCGACCTCTTCTA Q|362|E Q|362|* T|363|R T|363|I 0 0 0 0 0.3979862697982878 P53886 0.9590039849281312 0.9476869702339172 0.9472420215606691 0.39412575960159296 0.5106108784675598 0.18422400951385495 50.24760672486599 50.0 1.0 no 11727 chrXIV_311733 30252 essential YNL172W 1097 + TTCTAAGGATATTGTTTTGA S|367|C S|367|F 0 0 0 0 -0.07932500958183428 P53886 0.945252001285553 0.9294660091400146 0.052010584622621536 0.04901592805981636 37.85864785480078 25.0 1.0 no 11728 chrXIV_311968r 30255 essential YNL172W 1335 - TCTAGTCTGATCATGTTTTG E|452|Q E|452|K R|450|T R|450|K 0 0 0 0 0.5492178540434921 P53886 0.956179976463318 0.9475290179252625 0.932735025882721 0.955805003643036 0.5388495922088623 0.8112093210220337 0.17672820389270782 1.0 43.55338078159218 35.0 1.0 no 11729 chrXIV_311985 30256 essential YNL172W 1349 + ACTAGAGAACTTAAAGCTTA L|451|V silent|CTA>TTA|L|451 0 0 0 0 0.22610749707829386 P53886 0.9512209892272948 0.1496686190366745 36.30225486983801 30.0 1.0 no 11730 chrXIV_312010r 30257 essential YNL172W 1377 - TACATAGCTTGTATTCTTGA M|465|I M|465|I 0 0 0 0 0.5383443763318122 P53886 0.9553959965705872 0.9553959965705872 0.4387459754943848 0.4387459754943848 42.00983567192589 30.0 1.0 no 11731 chrXIV_312045r 30258 essential YNL172W 1412 - CCAAAATCAGGCAACTTTCA L|477|F silent|TTG>TTA|L|477 0 0 0 0 0.5562548791088395 P53886 0.9587849974632264 0.03316783532500267 43.208984823226096 40.0 1.0 no 11732 chrXIV_312502 30263 essential YNL172W 1863 + GTGCTACCAAGAATTGTTAT L|623|V silent|CTA>TTA|L|623 P|624|A P|624|S 0 0 0 0 1.1233510087200986 P53886 42.98495185785277 35.0 1.0 no 11733 chrXIV_312642 30265 essential YNL172W 2003 + ATCTTACTATGTACCGAAAA S|669|C S|669|F Y|670|* silent|TAC>TAT|Y|670 0 0 0 0 0.01838808262919614 P53886 38.139155161857154 30.0 1.0 no 11734 chrXIV_312655r 30266 essential YNL172W 2019 - TTCGATTCTGAATCCATTTT silent|TCG>TCC|S|679 silent|TCG>TCA|S|679 0 0 0 0 -0.09591381436673907 P53886 42.616481105254756 30.0 1.0 no 11735 chrXIV_312722r 30267 essential YNL172W 2086 - AATCGATGGCGGTTCATCTA silent|TCG>TCC|S|701 silent|TCG>TCA|S|701 0 0 0 0 -0.8053381016228268 P53886 48.00392189604975 45.0 1.0 no 11736 chrXIV_312721r 30268 essential YNL172W 2085 - ATCGATGGCGGTTCATCTAA silent|TCG>TCC|S|701 silent|TCG>TCA|S|701 0 0 0 0 -0.06079521393982296 P53886 48.00392189604975 45.0 1.0 no 11737 chrXIV_312852 30274 essential YNL172W 2213 + TCCAAGAAGTTTCAAAATCT P|739|R P|739|L P|739|A P|739|S 0 0 0 0 0.8585206406290145 P53886 37.62797354553118 30.0 1.0 no 11738 chrXIV_312927 30275 essential YNL172W 2288 + CATCCTTTCCAGCTTTAAAG I|764|M silent|ATC>ATT|I|764 L|765|V L|765|F 0 0 0 0 0.4690623360515909 P53886 46.32365124995562 40.0 1.0 no 11739 chrXIV_312930r 30276 essential YNL172W 2294 - TATCCACTTTAAAGCTGGAA D|771|H D|771|N silent|GTG>GTC|V|770 silent|GTG>GTA|V|770 0 0 0 0 0.4592085862892127 P53886 41.76232121473595 35.0 1.0 no 11740 chrXIV_313043 30278 essential YNL172W 2404 + ACAACTTGGAGTTATTAGAT D|802|E silent|GAC>GAT|D|802 N|803|K silent|AAC>AAT|N|803 0 0 0 0 -0.02178855195649876 P53886 38.74612289603015 30.0 1.0 no 11741 chrXIV_312935r 30279 essential YNL172W 2299 - GTCTTTATCCACTTTAAAGC D|773|H D|773|N 0 0 0 0 0.9093605820457572 P53886 43.537179771351525 35.0 1.0 no 11742 chrXIV_313044 30280 essential YNL172W 2405 + CAACTTGGAGTTATTAGATA N|803|K silent|AAC>AAT|N|803 0 0 0 0 -0.4977954877107194 P53886 37.74965894499985 30.0 1.0 no 11743 chrXIV_313067r 30281 essential YNL172W 2431 - GGCACTACACCTTTGTAAAT A|817|P A|817|T S|816|T S|816|N 1 Series([], Name: modification, dtype: object) 0 0 0 0.7216524794840381 P53886 45.572277927773314 40.0 1.0 no 11744 chrXIV_313088r 30283 essential YNL172W 2452 - ACTTCTTATACTATTGATAA S|824|T S|824|N R|823|T R|823|K 0 0 0 0 0.4729515000367963 P53886 34.70741047277096 20.0 1.0 no 11745 chrXIV_313246 30284 essential YNL172W 2607 + GCAAGTCAAGTTCCACTGGA A|870|G A|870|V Q|872|E Q|872|* 1 Series([], Name: modification, dtype: object) 0 0 0 1.4475905842594523 P53886 51.01396487820796 50.0 1.0 no 11746 chrXIV_313382 30286 essential YNL172W 2743 + TATCACTATTAGCTTATTAC S|916|* S|916|L L|917|V silent|CTA>TTA|L|917 0 0 0 0 -0.2407424616582997 P53886 37.420144294066404 25.0 1.0 no 11747 chrXIV_313430r 30287 essential YNL172W 2794 - TATCTGGGCATATTCTGTCT Q|937|H silent|CAG>CAA|Q|937 0 0 0 0 -0.6061776143153105 P53886 49.43431826148275 40.0 1.0 no 11748 chrXIV_313445r 30288 essential YNL172W 2809 - TTTCTTTTGAGCTAGTATCT K|942|N silent|AAG>AAA|K|942 0 0 0 0 -1.2330019152692897 P53886 44.320989990818816 30.0 1.0 no 11749 chrXIV_313472 30289 essential YNL172W 2833 + TCGCTAAAATCATGGCTTTG A|946|G A|946|V F|945|L silent|TTC>TTT|F|945 0 0 0 0 0.13558992290288574 P53886 42.598073101879436 40.0 1.0 no 11750 chrXIV_313545 30291 essential YNL172W 2906 + ACCAATATCTACCCAAAAAT P|970|R P|970|L P|970|A P|970|S 0 0 0 0 0.8607119427261629 P53886 39.24229072810999 30.0 1.0 no 11751 chrXIV_313576r 30292 essential YNL172W 2940 - AACACGGAAATTAAGTTGAG silent|GTG>GTC|V|986 silent|GTG>GTA|V|986 V|986|L V|986|M 0 0 0 0 0.25046701346996725 P53886 35.01796082950568 35.0 1.0 no 11752 chrXIV_313641 30294 essential YNL172W 3002 + AGCACACGATATTGTGGAGT A|1002|G A|1002|V H|1003|D H|1003|Y 0 0 0 0 -0.31544400468804146 P53886 47.33182889898228 45.0 1.0 no 11753 chrXIV_313642 30295 essential YNL172W 3003 + GCACACGATATTGTGGAGTG H|1003|D H|1003|Y A|1002|G A|1002|V 0 0 0 0 -0.16662527357490006 P53886 47.23160673443266 50.0 1.0 no 11754 chrXIV_313643 30296 essential YNL172W 3004 + CACACGATATTGTGGAGTGG H|1003|D H|1003|Y H|1003|Q silent|CAC>CAT|H|1003 0 0 0 0 -0.8031526351538372 P53886 45.96304938389017 50.0 1.0 no 11755 chrXIV_313669 30298 essential YNL172W 3030 + TTTCATGCCGGTGTTAGCTC H|1012|D H|1012|Y 0 0 0 0 -0.2826037482152839 P53886 54.89462354487381 50.0 1.0 no 11756 chrXIV_313783 30305 essential YNL172W 3144 + CTTCTCGGACTGGGACTTAA L|1050|V L|1050|F silent|CTC>CTG|L|1050 silent|CTC>CTT|L|1050 0 0 0 0 0.6624436945533831 P53886 0.9512209892272948 0.9587849974632264 0.0 0.0 48.579502441301315 50.0 1.0 no 11757 chrXIV_313966r 30310 essential YNL172W 3330 - TTCAAATCGCTAGATCCGCT L|1116|F silent|TTG>TTA|L|1116 0 0 0 0 -0.35143504510626816 P53886 48.38712110060595 45.0 1.0 no 11758 chrXIV_313993 30311 essential YNL172W 3354 + GATCTAAAACTACAAACTGC L|1120|V silent|CTA>TTA|L|1120 0 0 0 0 0.4415437080957715 P53886 35.327471258882724 35.0 1.0 no 11759 chrXIV_314002 30312 essential YNL172W 3363 + CTACAAACTGCTGGTATTAT Q|1123|E Q|1123|* 0 0 0 0 -0.3050855559000041 P53886 41.077949362167146 35.0 1.0 no 11760 chrXIV_314184 30318 essential YNL172W 3545 + TCAGACGAAACTGAGAAAGT Q|1183|E Q|1183|* T|1184|R T|1184|M 0 0 0 0 0.18603803065250304 P53886 37.51113585911128 40.0 1.0 no 11761 chrXIV_314292r 30321 essential YNL172W 3656 - TCTCTAATAACTTCGTAGTC E|1225|Q E|1225|K E|1225|D silent|GAG>GAA|E|1225 0 0 0 0 0.3371648561787011 P53886 40.798089119135064 35.0 1.0 no 11762 chrXIV_314350 30322 essential YNL172W 3711 + ATACCAGAGAATTCGCAAAT P|1239|A P|1239|S P|1239|R P|1239|L 0 0 0 0 0.15725074136982126 P53886 40.128361477221226 35.0 1.0 no 11763 chrXIV_314481r 30323 essential YNL172W 3845 - CTCGGTACATTAATAATTCA R|1288|P R|1288|Q 0 0 0 0 -4.880486953848749 P53886 38.31030652982133 30.0 1.0 yes 11764 chrXIV_314499r 30324 essential YNL172W 3863 - TCATATTGGATGCCCATTCT M|1294|I M|1294|I 0 0 0 0 -0.22809677881990195 P53886 50.50906617998828 40.0 1.0 no 11765 chrXIV_314507 30325 essential YNL172W 3868 + GGGCATCCAATATGATTTTA A|1291|G A|1291|V S|1292|C S|1292|F 0 0 0 0 0.7935131432465647 P53886 44.4693109709097 35.0 1.0 no 11766 chrXIV_314508 30326 essential YNL172W 3869 + GGCATCCAATATGATTTTAT A|1291|G A|1291|V S|1292|C S|1292|F 0 0 0 0 0.6723723671366908 P53886 42.120948705502094 30.0 1.0 no 11767 chrXIV_327597r 30327 essential YNL163C 2454 + GATCCCGTCATAGAATCAAC P|820|A P|820|S P|820|R P|820|L RIA1 RIbosome Assembly 1110.0 0 0 0 0 -1.0906517262810422 P53893 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.7216989994049072 0.7111985683441162 0.5030649304389954 0.2856395244598389 45.51215360115043 45.0 0.0 no 11768 chrXIV_327594 30328 essential YNL163C 2460 - CTTCCAGTTGATTCTATGAC G|826|A G|826|E G|826|R G|826|R RIA1 RIbosome Assembly 1110.0 0 0 0 0 -0.15167952457558906 P53893 0.9499930143356324 0.9438679814338684 0.941340982913971 0.941340982913971 0.7355887889862059 1.0 0.5034780502319336 0.5034780502319336 45.705484024252655 40.0 0.0 no 11769 chrXIV_327693r 30330 essential YNL163C 2358 + TTCAGAACGTTCCCATTAAG F|787|L silent|TTC>TTT|F|787 RIA1 RIbosome Assembly 1110.0 0 0 0 0 0.542418196462486 P53893 0.9387490153312684 1.0 44.2425933035301 40.0 0.0 no 11770 chrXIV_327709 30331 essential YNL163C 2345 - TTCTGAATGTAATCTTGTAC R|788|T R|788|K RIA1 RIbosome Assembly 1110.0 0 0 0 0 0.7098492086535224 P53893 0.932735025882721 0.955805003643036 0.1766217201948166 0.36088964343070973 37.674309714659216 30.0 0.0 no 11771 chrXIV_327756 30333 essential YNL163C 2298 - CTTCCCAGCTGTGAATTCTG G|772|A G|772|E G|772|R G|772|R RIA1 RIbosome Assembly 1110.0 0 0 0 0 0.1441843273954516 P53893 0.9499930143356324 0.9438679814338684 0.941340982913971 0.941340982913971 0.6459884643554688 0.4551593065261841 0.13109129667282104 0.13109129667282104 52.12911720156643 50.0 0.0 no 11772 chrXIV_327759r 30334 essential YNL163C 2292 + CCACCGCAGAATTCACAGCT P|766|A P|766|S P|765|R P|765|L RIA1 RIbosome Assembly 1110.0 0 0 0 0 0.4170582961829405 P53893 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.1083603948354721 0.2001543790102005 0.02181871049106121 0.009163070470094679 53.812663927829476 55.00000000000001 0.0 no 11773 chrXIV_327859 30336 essential YNL163C 2195 - ATCTCTCTGTTAAATCTTTT R|738|T R|738|K E|737|D silent|GAG>GAA|E|737 RIA1 RIbosome Assembly 1110.0 0 0 0 0 0.3239010246930498 P53893 0.932735025882721 0.955805003643036 0.94931298494339 0.0 0.0 0.0 40.130154743465255 25.0 0.0 no 11774 chrXIV_327927r 30338 essential YNL163C 2124 + CACACATACGTTGAAAATAC H|709|Q silent|CAC>CAT|H|709 T|710|R T|710|I RIA1 RIbosome Assembly 1110.0 0 0 0 0 -0.7638380612766517 P53893 0.9588389992713928 0.9476869702339172 0.9472420215606691 0.2472937703132629 0.044166211038827896 0.7426841259002686 35.51777258460333 35.0 0.0 no 11775 chrXIV_327990 30340 essential YNL163C 2064 - ACCAACTTGCTCATTTCCAC L|694|F silent|TTG>TTA|L|694 V|695|L V|695|I RIA1 RIbosome Assembly 1110.0 0 0 0 0 0.6011400697142085 P53893 0.9587849974632264 0.9539830088615416 0.9574310183525084 0.011996340937912464 0.14705681800842285 0.4360703825950623 50.592257278386576 45.0 0.0 no 11776 chrXIV_327999 30342 essential YNL163C 2055 - CTCATTTCCACAGGATTGGC M|691|I M|691|I RIA1 RIbosome Assembly 1110.0 0 0 0 0 0.0072287505410695285 P53893 0.9553959965705872 0.9553959965705872 0.1016240045428276 0.1016240045428276 51.91247854294522 50.0 0.0 no 11777 chrXIV_328033 30345 essential YNL163C 2021 - CACGAACGATTGGCGTAAAA R|680|P R|680|H V|679|L V|679|I RIA1 RIbosome Assembly 1110.0 0 0 0 0 0.5896635859910342 P53893 0.9099509716033936 0.9570810198783876 0.9539830088615416 0.9574310183525084 0.0 0.0 0.07298529148101808 0.03063839673995972 40.550711466004316 45.0 0.0 no 11778 chrXIV_328065r 30346 essential YNL163C 1986 + GTACAAGGCGTCAATCTAGC Q|664|E Q|664|* RIA1 RIbosome Assembly 1110.0 0 0 0 0 -0.660379342870319 P53893 0.9590039849281312 1.0 48.083302050128744 50.0 0.0 no 11779 chrXIV_328140 30350 essential YNL163C 1914 - ATACCGACTATATTTCCTGA G|644|A G|644|D G|644|R G|644|S RIA1 RIbosome Assembly 1110.0 0 0 0 0 -1.4092724773777228 P53893 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.370233952999115 0.005275649484246968 0.0041436608880758286 0.028745997697114944 44.90954898296354 35.0 0.0 no 11780 chrXIV_328191r 30353 essential YNL163C 1860 + ACGCATTTATATTTGTTTAT H|622|D H|622|Y T|621|R T|621|M RIA1 RIbosome Assembly 1110.0 0 0 0 0 0.3439622695500503 P53893 0.9473130106925964 0.9489949941635132 0.9476869702339172 0.9502379894256592 0.7713528871536255 0.03812697902321816 0.4717361330986023 0.0952480360865593 38.29364300505074 20.0 0.0 no 11781 chrXIV_328192r 30354 essential YNL163C 1859 + TACGCATTTATATTTGTTTA T|621|R T|621|M H|622|D H|622|Y RIA1 RIbosome Assembly 1110.0 0 0 0 0 0.1914930031194145 P53893 0.9476869702339172 0.9502379894256592 0.9473130106925964 0.9489949941635132 0.4717361330986023 0.0952480360865593 0.7713528871536255 0.03812697902321816 37.74018497323999 20.0 0.0 no 11782 chrXIV_328242 30356 essential YNL163C 1812 - GGACATTTTGGATCATATTT C|610|S C|610|Y RIA1 RIbosome Assembly 1110.0 0 0 0 0 0.3535312535945542 P53893 0.9421560168266296 0.9290120005607604 0.4072578549385071 1.0 41.16137793595789 30.0 0.0 no 11783 chrXIV_328302r 30360 essential YNL163C 1749 + GCATTTGCAAGAATATACAG A|584|G A|584|V RIA1 RIbosome Assembly 1110.0 0 0 0 0 0.5084454215336087 P53893 0.9484469890594482 0.9504740238189696 1.0 0.008412457071244717 38.78781061733804 35.0 0.0 no 11784 chrXIV_328327r 30361 essential YNL163C 1724 + TGACGAAAAGGAAGAATGCT D|576|E silent|GAC>GAT|D|576 RIA1 RIbosome Assembly 1110.0 0 0 0 0 1.286116121382573 P53893 0.9532920122146606 1.0 37.18050438652932 40.0 0.0 no 11785 chrXIV_328389 30362 essential YNL163C 1665 - TGCTTAATACTCTCCAAAAG K|561|N silent|AAG>AAA|K|561 RIA1 RIbosome Assembly 1110.0 0 0 0 0 0.4378169580520022 P53893 0.9355990290641784 0.4922915697097778 39.358855461850226 35.0 0.0 no 11786 chrXIV_328426 30363 essential YNL163C 1628 - ATTCAAACATTGAACTTAGA E|549|Q E|549|K RIA1 RIbosome Assembly 1110.0 0 0 0 0 1.0652706931049738 P53893 0.956179976463318 0.9475290179252625 0.4924585223197937 0.7538523077964783 34.22360532929713 25.0 0.0 no 11787 chrXIV_328485r 30365 essential YNL163C 1566 + TCAGATAGTCAAGATAACTT S|523|* S|523|L RIA1 RIbosome Assembly 1110.0 0 0 0 0 -2.6902163288052456 P53893 0.9298099875450134 0.32471901178359985 37.12933889990643 30.0 0.0 yes 11788 chrXIV_328462 30366 essential YNL163C 1592 - TGTCAGTTGGTACAAAATCT D|537|H D|537|N RIA1 RIbosome Assembly 1110.0 0 0 0 0 -0.4054194418300193 P53893 0.9486550092697144 0.956179976463318 0.11300165951251985 0.4566937685012818 41.18419950512907 35.0 0.0 no 11789 chrXIV_328526 30367 essential YNL163C 1528 - TTCAAATTCTAAATCCAAGG E|516|Q E|516|K RIA1 RIbosome Assembly 1110.0 0 0 0 0 0.5943273579354041 P53893 0.956179976463318 0.9475290179252625 0.5306013822555542 0.7807558178901672 36.02700982711684 30.0 0.0 no 11790 chrXIV_328533 30368 essential YNL163C 1521 - TCTAAATCCAAGGCGGAAGA E|514|Q E|514|K RIA1 RIbosome Assembly 1110.0 0 0 0 0 -0.3619268239718953 P53893 0.956179976463318 0.9475290179252625 0.5845535397529602 0.9238574504852296 43.82041026369273 45.0 0.0 no 11791 chrXIV_328540r 30369 essential YNL163C 1511 + TTCAGAGCCTTCTTCCGCCT S|505|* S|505|L RIA1 RIbosome Assembly 1110.0 0 0 0 0 -1.9923391370311159 P53893 0.9298099875450134 0.8086104393005371 61.23551563886264 55.00000000000001 0.0 no 11792 chrXIV_328578 30370 essential YNL163C 1476 - TCATTATTTCTTGAAGGTTT D|499|H D|499|N RIA1 RIbosome Assembly 1110.0 0 0 0 0 -0.04097530340689204 P53893 0.9486550092697144 0.956179976463318 0.10574685037136078 0.4257262647151947 39.74819812291543 25.0 0.0 no 11793 chrXIV_328604 30371 essential YNL163C 1450 - TGTCTGTTCTCCTACTTCGG Q|489|H silent|CAG>CAA|Q|489 RIA1 RIbosome Assembly 1110.0 0 0 0 0 0.2698552408500968 P53893 0.9570760130882264 0.12387485802173615 53.95548379321724 50.0 0.0 no 11794 chrXIV_328613 30372 essential YNL163C 1441 - TCCTACTTCGGGGGTCATAA G|487|R G|487|R G|487|A G|487|E RIA1 RIbosome Assembly 1110.0 0 0 0 0 0.2378778622967595 P53893 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.7198814749717712 0.7198814749717712 0.9737231731414796 1.0 52.35563584012402 50.0 0.0 no 11795 chrXIV_328788 30375 essential YNL163C 1266 - GCTATCCTCTTAGATTCAAC A|429|P A|429|T R|427|S silent|AGG>AGA|R|427 RIA1 RIbosome Assembly 1110.0 0 1 0 0 -0.38662369658793744 P53893 0.9573720097541808 0.9523990154266356 0.9087679982185364 0.3312760293483734 0.5441276431083679 0.672536313533783 46.10924219263904 40.0 0.0 no 11796 chrXIV_328803 30376 essential YNL163C 1251 - TCAACAGGTAATTCTTCTCT E|424|Q E|424|K V|423|L V|423|I RIA1 RIbosome Assembly 1110.0 0 0 0 0 0.38783668305587016 P53893 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.18750208616256714 0.2779325842857361 0.2662900686264038 0.1918802410364151 43.54122239760886 35.0 0.0 no 11797 chrXIV_328865 30377 essential YNL163C 1189 - TTCTTTATCACATGTCTTCA E|403|Q E|403|K RIA1 RIbosome Assembly 1110.0 0 0 0 0 0.1071827716990708 P53893 0.956179976463318 0.9475290179252625 0.3062579035758972 0.6300549507141113 44.15038499556379 30.0 0.0 no 11798 chrXIV_328889 30378 essential YNL163C 1165 - TTTCAGAAGTCTTGGATCCA silent|CTG>CTC|L|394 silent|CTG>CTA|L|394 RIA1 RIbosome Assembly 1110.0 0 0 0 0 -0.043875597205173984 P53893 47.299135945361 40.0 0.0 no 11799 chrXIV_329032r 30380 essential YNL163C 1019 + ACAATTGTTAAGAACTATCA Q|341|E Q|341|* RIA1 RIbosome Assembly 1110.0 0 0 0 0 0.3564217136632215 P53893 0.9590039849281312 1.0 34.52496056171969 25.0 0.0 no 11800 chrXIV_329069r 30382 essential YNL163C 982 + AGCTACTTGCACGTGATCTA L|329|V silent|CTA>TTA|L|329 L|330|V L|330|F RIA1 RIbosome Assembly 1110.0 0 0 0 0 0.5933319699578208 P53893 0.9512209892272948 0.9512209892272948 0.9587849974632264 1.0 0.4155338704586029 0.2635789513587952 49.45356915495779 45.0 0.0 no 11801 chrXIV_329297r 30386 essential YNL163C 754 + AACAAAAATTAGGCGCTAAA Q|253|E Q|253|* RIA1 RIbosome Assembly 1110.0 0 0 0 0 0.3827658404470409 P53893 0.9590039849281312 0.509158194065094 34.260542317110264 30.0 0.0 no 11802 chrXIV_329354r 30389 essential YNL163C 697 + TTGCTTCCGCAATTGATGGT A|234|G A|234|V S|235|C S|235|F RIA1 RIbosome Assembly 1110.0 0 0 0 0 -0.5168650075961659 P53893 0.9484469890594482 0.9504740238189696 0.945252001285553 0.9294660091400146 0.027520515024662014 0.0086240004748106 0.0021838375832885504 0.0013866937952116132 50.8684112153997 45.0 0.0 no 11803 chrXIV_329468r 30391 essential YNL163C 583 + GACAATTGGATGATTTATTT Q|196|E Q|196|* RIA1 RIbosome Assembly 1110.0 0 0 0 0 -1.6487409389083585 P53893 0.9590039849281312 0.03044584952294826 36.38935272694954 25.0 0.0 no 11804 chrXIV_329482r 30392 essential YNL163C 569 + TTTCGCAAACGAGAGACAAT F|191|L silent|TTC>TTT|F|191 A|192|G A|192|V RIA1 RIbosome Assembly 1110.0 0 0 0 0 -0.7074133454736903 P53893 0.9387490153312684 0.9484469890594482 0.9504740238189696 0.020194031298160556 0.15109388530254364 0.13372255861759186 40.09200818006389 40.0 0.0 no 11805 chrXIV_329510r 30393 essential YNL163C 541 + AACAAGTCAACTCAGTTATC Q|182|E Q|182|* RIA1 RIbosome Assembly 1110.0 0 0 0 0 0.5226201823194327 P53893 0.9590039849281312 0.06172839552164078 38.993953577898885 35.0 0.0 no 11806 chrXIV_329511r 30394 essential YNL163C 540 + GAACAAGTCAACTCAGTTAT Q|182|E Q|182|* RIA1 RIbosome Assembly 1110.0 0 0 0 0 0.4171174300495787 P53893 0.9590039849281312 0.06172839552164078 39.3223601202202 35.0 0.0 no 11807 chrXIV_329545 30395 essential YNL163C 509 - ACAAGTGAATATAAGCTTCT L|176|F silent|TTG>TTA|L|176 RIA1 RIbosome Assembly 1110.0 0 0 0 0 0.5494589490856856 P53893 0.9587849974632264 0.014148525893688204 37.768284323243904 30.0 0.0 no 11808 chrXIV_329601 30396 essential YNL163C 453 - ATCTTATTCAATACTAAAAT K|157|N silent|AAG>AAA|K|157 RIA1 RIbosome Assembly 1110.0 0 0 0 0 -0.9009023305163666 P53893 0.9355990290641784 0.0 30.220245247131462 15.0 0.0 no 11809 chrXIV_329642 30397 essential YNL163C 412 - ACATTGTCTCAACACTGTGA C|144|S C|144|Y RIA1 RIbosome Assembly 1110.0 0 0 0 0 0.8757563389058798 P53893 0.9421560168266296 0.9290120005607604 0.06703382730484009 0.008657056838274002 45.10256569497346 40.0 0.0 no 11810 chrXIV_329679r 30400 essential YNL163C 372 + GTACTGGTTGATGTCGTAGA L|126|V silent|CTG>TTG|L|126 RIA1 RIbosome Assembly 1110.0 0 0 0 0 0.012798869316983107 P53893 0.9512209892272948 0.009883189573884009 48.04238301217959 45.0 0.0 no 11811 chrXIV_329871 30405 essential YNL163C 183 - ATACCACGTAGTTGTTCGTC G|67|A G|67|D G|67|R G|67|S RIA1 RIbosome Assembly 1110.0 0 0 0 0 -1.8578471700803108 P53893 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.0 0.0 0.0 0.0 49.40152551880453 45.0 0.0 no 11812 chrXIV_332741r 30413 essential YNL161W 147 - TTGCTACTAAATCCTGCAGC S|55|T S|55|N S|54|T S|54|N CBK1 Cell wall Biosynthesis Kinase 756.0 0 0 0 0 0.9289625001633725 P53894 0.9512869715690612 0.9536849856376648 0.9512869715690612 0.9536849856376648 48.33806016175765 45.0 1.0 no 11813 chrXIV_333007 30424 essential YNL161W 410 + ACAATTACCCCAATTATCAC Q|138|E Q|138|* CBK1 Cell wall Biosynthesis Kinase 756.0 0 0 0 0 0.5593843258856578 P53894 0.9590039849281312 0.23288509249687195 43.48096495720768 35.0 1.0 no 11814 chrXIV_333026r 30426 essential YNL161W 432 - GACTCTATAGAATATTGGCC E|150|D silent|GAG>GAA|E|150 E|150|Q E|150|K CBK1 Cell wall Biosynthesis Kinase 756.0 0 0 0 0 0.55369881232137 P53894 0.94931298494339 0.956179976463318 0.9475290179252625 0.5414223074913025 0.1531868577003479 0.1540059596300125 43.727633373517335 40.0 1.0 no 11815 chrXIV_333031r 30427 essential YNL161W 437 - ACTCTGACTCTATAGAATAT E|152|Q E|152|K E|152|D silent|GAG>GAA|E|152 CBK1 Cell wall Biosynthesis Kinase 756.0 0 0 0 0 0.10645994667418048 P53894 0.956179976463318 0.9475290179252625 0.94931298494339 0.2352136522531509 0.19426122307777405 0.4797817766666413 38.47496625892711 30.0 1.0 no 11816 chrXIV_333093 30429 essential YNL161W 496 + TCCACCAACCGCAAACGCTA H|167|D H|167|Y F|166|L silent|TTC>TTT|F|166 CBK1 Cell wall Biosynthesis Kinase 756.0 0 0 0 0 0.6729264253814496 P53894 0.9473130106925964 0.9489949941635132 0.9387490153312684 52.07495012618637 55.00000000000001 1.0 no 11817 chrXIV_333101r 30433 essential YNL161W 507 - CCATTGCTCCGTAGCGTTTG G|176|R G|176|R S|174|T S|174|N CBK1 Cell wall Biosynthesis Kinase 756.0 0 1 0 0 0.23574495377573995 P53894 0.941340982913971 0.941340982913971 0.9512869715690612 0.9536849856376648 0.10393980145454408 0.10393980145454408 55.697254116212385 55.00000000000001 1.0 no 11818 chrXIV_333123 30437 essential YNL161W 526 + GGTCATATTCAAGCGGGTTA S|177|* S|177|L CBK1 Cell wall Biosynthesis Kinase 756.0 1 Series([], Name: modification, dtype: object) 0 0 0 -1.3261108984791206 P53894 0.9298099875450134 0.08738009631633759 48.986530792801496 45.0 1.0 no 11819 chrXIV_333407 30440 essential YNL161W 810 + CGACCAGATTTGTTGACTAA P|272|A P|272|S P|272|R P|272|L CBK1 Cell wall Biosynthesis Kinase 756.0 0 0 0 0 0.1715786570602169 P53894 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.11216101795434953 0.10993079096078873 0.028678279370069507 0.019452949985861775 43.30294729237977 40.0 1.0 no 11820 chrXIV_333410r 30441 essential YNL161W 816 - GTTCCTTTAGTCAACAAATC G|278|A G|278|E G|278|R G|278|R CBK1 Cell wall Biosynthesis Kinase 756.0 0 0 0 0 0.598955575056496 P53894 0.9499930143356324 0.9438679814338684 0.941340982913971 0.941340982913971 0.9931132793426514 1.0 0.6169795989990234 0.6169795989990234 41.63973494174211 35.0 1.0 no 11821 chrXIV_333572 30446 essential YNL161W 975 + TCTAGGCAATTGAGTTCTTT S|326|C S|326|F Q|328|E Q|328|* CBK1 Cell wall Biosynthesis Kinase 756.0 0 0 0 0 0.466779953999334 P53894 0.945252001285553 0.9294660091400146 0.9590039849281312 0.033699680119752884 0.031490277498960495 0.2850165665149689 0.22499999403953552 -1.1064000129699707 0.3704000115394592 45.038254863776615 35.0 1.0 no 11822 chrXIV_333717r 30449 essential YNL161W 1123 - TTTCATTGCATATATTTTTC M|380|I M|380|I CBK1 Cell wall Biosynthesis Kinase 756.0 0 0 0 0 0.7502606773247079 P53894 0.9553959965705872 0.9553959965705872 0.009525211527943613 0.009525211527943613 37.83396194136037 20.0 1.0 no 11823 chrXIV_333769 30450 essential YNL161W 1172 + GGACCAATTAGCACACGTCA D|392|E silent|GAC>GAT|D|392 Q|393|E Q|393|* CBK1 Cell wall Biosynthesis Kinase 756.0 0 0 0 0 -0.2583724682270256 P53894 0.9532920122146606 0.9590039849281312 0.3261171281337738 0.0 -0.4629999995231629 49.66407249115486 50.0 1.0 no 11824 chrXIV_333772r 30451 essential YNL161W 1178 - CAGCCTTGACGTGTGCTAAT A|399|P A|399|T K|398|N silent|AAG>AAA|K|398 CBK1 Cell wall Biosynthesis Kinase 756.0 0 0 0 0 -1.4505092270495108 P53894 0.9573720097541808 0.9523990154266356 0.9355990290641784 0.003550658700987697 0.0027384276036173105 0.0047417525202035895 -0.9667999744415284 51.30601597295321 50.0 1.0 no 11825 chrXIV_333807 30453 essential YNL161W 1210 + TGGCTGGAAGTGATTCTCCA A|405|G A|405|V CBK1 Cell wall Biosynthesis Kinase 756.0 0 0 0 0 -0.1787076812751247 P53894 0.9484469890594482 0.9504740238189696 0.0037379947025328883 0.17286905646324158 52.33477396665153 50.0 1.0 no 11826 chrXIV_333862 30455 essential YNL161W 1265 + TCAATACTTATATTTAATCA Q|423|E Q|423|* Y|424|* silent|TAC>TAT|Y|424 CBK1 Cell wall Biosynthesis Kinase 756.0 0 0 0 0 0.9615864763777764 P53894 0.9590039849281312 1.0 -0.5297999978065491 31.80080681061776 15.0 1.0 no 11827 chrXIV_333983 30458 essential YNL161W 1386 + ATCGAAACCATTCATAAATT I|463|M silent|ATC>ATT|I|463 CBK1 Cell wall Biosynthesis Kinase 756.0 0 0 0 0 0.5689795856886121 P53894 0.9598389863967896 0.002082310384139418 35.60725793075681 25.0 1.0 no 11828 chrXIV_334069 30459 essential YNL161W 1472 + ATCTGATTTCGGGTTGTCTA S|492|C S|492|F CBK1 Cell wall Biosynthesis Kinase 756.0 0 0 0 0 0.6343545882679158 P53894 0.945252001285553 0.9294660091400146 0.02279774285852909 0.0008191546658053994 48.54418651221016 40.0 1.0 no 11829 chrXIV_334136 30461 essential YNL161W 1539 + CAACAAGATGAGGCAACTAA Q|515|E Q|515|* CBK1 Cell wall Biosynthesis Kinase 756.0 0 0 0 0 -0.3386474943731794 P53894 0.9590039849281312 1.0 38.405179721276795 40.0 1.0 no 11830 chrXIV_339616 30465 essential YNL158W 4 + TCCGGCCTCAGAATGTTCAC R|3|G R|3|W silent|GTC>GTG|V|2 silent|GTC>GTT|V|2 0 0 0 0 0.2100133194459431 P53896 0.8994590044021606 0.9448130130767822 54.38663878694575 55.00000000000001 1.0 no 11831 chrXIV_339823r 30469 essential YNL158W 214 - CAACTCCAAGTCAGTGGTAT E|77|D silent|GAG>GAA|E|77 E|77|Q E|77|K 0 1 0 0 -0.2980766018222293 P53896 0.94931298494339 0.956179976463318 0.9475290179252625 0.5790553092956543 0.5967825055122375 0.8499554395675659 47.807236768986854 45.0 1.0 no 11832 chrXIV_339851 30470 essential YNL158W 239 + TACTACGTATATTGAACTGG T|81|S T|81|I T|82|R T|82|M 0 1 0 0 -0.2386453428475989 P53896 0.9491789937019348 0.9472420215606691 0.9476869702339172 0.9502379894256592 0.7607976198196411 0.1969456374645233 0.3979400396347046 0.22819289565086365 38.33195406573452 35.0 1.0 no 11833 chrXIV_339962 30472 essential YNL158W 350 + ACCACGTTTCACTGAATTTC P|118|R P|118|L P|118|A P|118|S 0 0 0 0 0.4516978230779529 P53896 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.012192493304610252 0.01673088222742081 0.2618783712387085 0.06189253926277161 45.28183205655654 40.0 1.0 no 11834 chrXIV_339963 30473 essential YNL158W 351 + CCACGTTTCACTGAATTTCA R|119|G R|119|C P|118|R P|118|L 0 0 0 0 0.02004322372020495 P53896 0.8994590044021606 0.8926740288734436 0.9432820081710817 0.9430609941482544 0.6026313304901123 0.1022651344537735 0.012192493304610252 0.01673088222742081 46.10489530447365 40.0 1.0 no 11835 chrXIV_346449r 30476 essential YNL152W 139 - TGCTCGATGTAGAGTGTTGC A|53|P A|53|T R|52|P R|52|Q INN1 required for INgressioN 409.0 0 0 0 0 -1.5026049279187732 P53901 0.9863749742507936 0.9780830144882202 0.8924970030784607 0.9239929914474488 0.04461831972002983 0.031692400574684136 0.0 0.0 50.772679924745944 50.0 1.0 no 11836 chrXIV_346451 30477 essential YNL152W 138 + AGCAACACTCTACATCGAGC S|47|R silent|AGC>AGT|S|47 N|48|K silent|AAC>AAT|N|48 INN1 required for INgressioN 409.0 0 0 0 0 0.26866365046868823 P53901 0.895359992980957 0.9597960114479064 0.0 0.10231368988752364 47.878123287634594 50.0 1.0 no 11837 chrXIV_346542 30479 essential YNL152W 229 + TCGAAGTTTACTGCGATAGA silent|GTC>GTG|V|77 silent|GTC>GTT|V|77 INN1 required for INgressioN 409.0 0 0 0 0 0.06287513727575401 P53901 42.816140475715535 40.0 1.0 no 11838 chrXIV_346574r 30480 essential YNL152W 264 - TCACATCTTCCAATTGGCAG C|94|S C|94|Y E|95|Q E|95|K INN1 required for INgressioN 409.0 0 0 0 0 -1.9691092885829728 P53901 0.968258023262024 0.95100998878479 0.9840490221977234 0.972000002861023 0.0 0.0 0.10187602788209917 0.10512099415063858 48.65659482989452 45.0 1.0 no 11839 chrXIV_346647r 30483 essential YNL152W 337 - ACTTCTTTTCAGTTCGTACC S|119|T S|119|N R|118|T R|118|K INN1 required for INgressioN 409.0 0 0 0 0 0.4049460653203047 P53901 0.9745349884033204 0.9785860180854796 0.900963008403778 0.9193329811096193 0.24525415897369385 1.0 49.25809808024087 40.0 1.0 no 11840 chrXIV_346759 30489 essential YNL152W 446 + GGACAGGTTGGATTCATCTA D|150|E silent|GAC>GAT|D|150 INN1 required for INgressioN 409.0 0 0 0 0 0.8611191861190568 P53901 0.9783369898796082 1.0 48.469613499442175 45.0 1.0 no 11841 chrXIV_346859r 30490 essential YNL152W 549 - TGACTTGTGCTAACACACTG S|189|T S|189|N INN1 required for INgressioN 409.0 0 0 0 0 0.21079698905500546 P53901 0.9669449925422668 0.9709960222244264 0.152637779712677 0.2848694920539856 44.647849501922686 45.0 1.0 no 11842 chrXIV_346990 30492 essential YNL152W 677 + TCCAACTTTTTCAGCATCCA P|227|R P|227|L P|227|A P|227|S INN1 required for INgressioN 409.0 0 0 0 0 0.1413751922433833 P53901 0.9589099884033204 0.9670220017433168 0.9839829802513124 0.9755030274391174 0.2863962948322296 0.5107811093330383 1.0 0.9791631698608398 50.61349355436613 40.0 1.0 no 11843 chrXIV_347149r 30493 essential YNL152W 839 - CTACCTTGTTAGATTCATTT V|286|L V|286|I K|285|N silent|AAG>AAA|K|285 INN1 required for INgressioN 409.0 0 0 0 0 -0.13748760161482745 P53901 0.9940739870071412 1.0010499954223633 0.912319004535675 0.183010995388031 0.07774114608764647 0.5685296654701233 43.380471058605 30.0 1.0 no 11844 chrXIV_347158 30495 essential YNL152W 845 + ATCTAACAAGGTAGATATTG S|283|C S|283|F N|284|K silent|AAC>AAT|N|284 INN1 required for INgressioN 409.0 0 0 0 0 -0.4159546309656222 P53901 0.9182299971580504 0.9007340073585509 0.9148370027542114 0.01573626697063446 0.015446648001670837 0.7591887712478638 35.56935297098471 30.0 1.0 no 11845 chrXIV_347996r 30498 essential YNL151C 503 + AAACATCGGACTATCCATGC N|169|K silent|AAC>AAT|N|169 I|170|M silent|ATC>ATT|I|170 RPC31 RNA Polymerase C 251.0 0 0 0 0 0.8601124721394339 P17890 0.8969295024871826 0.13757199048995972 45.20345098967107 45.0 0.0 no 11846 chrXIV_348048 30499 essential YNL151C 454 - ATCATCGGCATTATTAAACT D|158|H D|158|N D|157|H D|157|N RPC31 RNA Polymerase C 251.0 0 0 0 0 -0.9228189775869526 P17890 0.359965443611145 0.9521087408065796 0.12976954877376554 0.375475138425827 39.96539253597143 30.0 0.0 no 11847 chrXIV_348174r 30500 essential YNL151C 325 + CCGATAAATATTTGAAAAAA silent|TCC>TCG|S|109 silent|TCC>TCT|S|109 RPC31 RNA Polymerase C 251.0 0 0 0 0 0.45964637949898796 P17890 29.106744402573327 20.0 0.0 no 11848 chrXIV_348225 30501 essential YNL151C 277 - GTCTTCGTCTAGGATTATGT D|99|H D|99|N E|98|Q E|98|K RPC31 RNA Polymerase C 251.0 0 0 0 0 0.4434962091747541 P17890 0.10902287811040877 0.4865529239177704 0.2253880351781845 0.2934386432170868 47.997278069997606 40.0 0.0 no 11849 chrXIV_348211r 30502 essential YNL151C 288 + GACGAAGACGATACTAATGA D|97|E silent|GAC>GAT|D|97 RPC31 RNA Polymerase C 251.0 0 0 0 0 -0.8073005894036884 P17890 1.0 37.639330263665215 40.0 0.0 no 11850 chrXIV_348226 30503 essential YNL151C 276 - TCTTCGTCTAGGATTATGTT D|99|H D|99|N E|98|Q E|98|K RPC31 RNA Polymerase C 251.0 0 0 0 0 -3.315094492118216 P17890 0.10902287811040877 0.4865529239177704 0.2253880351781845 0.2934386432170868 45.4909175326149 35.0 0.0 yes 11851 chrXIV_348295 30506 essential YNL151C 207 - CTCATTGATCCGGTATAAAA M|75|I M|75|I RPC31 RNA Polymerase C 251.0 0 0 0 0 0.5913975148321425 P17890 0.28558656573295593 0.28558656573295593 40.45574841078866 35.0 0.0 no 11852 chrXIV_348296 30507 essential YNL151C 206 - TCATTGATCCGGTATAAAAT M|75|I M|75|I RPC31 RNA Polymerase C 251.0 0 0 0 0 0.7699594021546762 P17890 0.28558656573295593 0.28558656573295593 38.78226832012143 30.0 0.0 no 11853 chrXIV_348364 30509 essential YNL151C 138 - GATCTTTCCTTATTTGTTAT R|52|T R|52|K RPC31 RNA Polymerase C 251.0 0 0 0 0 0.7982443800582624 P17890 0.20721910893917084 0.8913250565528871 42.73554727489028 25.0 0.0 no 11854 chrXIV_348388r 30511 essential YNL151C 111 + TCCATCCCATTGCCCATCAA silent|TCC>TCG|S|38 silent|TCC>TCT|S|38 S|38|C S|38|F RPC31 RNA Polymerase C 251.0 0 0 0 0 -0.2455951665824989 P17890 0.02656562626361847 0.03277114406228065 57.98993199938377 50.0 0.0 no 11855 chrXIV_348441 30512 essential YNL151C 61 - ATCTCCATAACCTAATCCGA D|27|H D|27|N G|26|A G|26|E RPC31 RNA Polymerase C 251.0 0 0 0 0 0.3047884164813981 P17890 0.0 0.0 0.8746914863586426 0.342360258102417 47.1499555639744 40.0 0.0 no 11856 chrXIV_348442 30513 essential YNL151C 60 - TCTCCATAACCTAATCCGAA G|26|A G|26|E D|27|H D|27|N RPC31 RNA Polymerase C 251.0 0 0 0 0 -0.014984234130600403 P17890 0.8746914863586426 0.342360258102417 0.0 0.0 45.733918149122594 40.0 0.0 no 11857 chrXIV_348445r 30515 essential YNL151C 54 + CTACCCTTCGGATTAGGTTA P|20|A P|20|S P|20|R P|20|L RPC31 RNA Polymerase C 251.0 0 0 0 0 0.07913352387253161 P17890 0.0 0.0 0.0 0.0 50.85094861619415 45.0 0.0 no 11858 chrXIV_349531 30518 essential YNL149C 206 - CATCATCTGGCTTGTCGATC D|75|H D|75|N D|74|H D|74|N PGA2 Processing of Gas1p and ALP 129.0 0 0 0 0 0.6667583394275887 P53903 0.084213986992836 0.3189722597599029 0.09620891511440276 0.4117248952388763 50.943775923351886 50.0 0.0 no 11859 chrXIV_349579 30519 essential YNL149C 158 - CTCGTTTGTCCTTTTCCACT R|59|P R|59|Q PGA2 Processing of Gas1p and ALP 129.0 0 0 0 0 0.4945437658091618 P53903 0.09088751673698424 0.2466994822025299 54.97506351251457 45.0 0.0 no 11860 chrXIV_349580 30520 essential YNL149C 157 - TCGTTTGTCCTTTTCCACTT R|59|P R|59|Q PGA2 Processing of Gas1p and ALP 129.0 0 0 0 0 0.9034480054393604 P53903 0.09088751673698424 0.2466994822025299 53.39827299297747 40.0 0.0 no 11861 chrXIV_349610 30521 essential YNL149C 127 - CTGCTTCTTCGCCAATTCCC K|48|N silent|AAG>AAA|K|48 K|47|N silent|AAG>AAA|K|47 PGA2 Processing of Gas1p and ALP 129.0 0 0 0 0 1.1475986363819335 P53903 0.021758532151579857 0.013375901617109777 57.72527098072168 55.00000000000001 0.0 no 11862 chrXIV_349628r 30522 essential YNL149C 106 + TCTTAAGAAATATCGCATCC silent|CTC>CTG|L|36 silent|CTC>CTT|L|36 PGA2 Processing of Gas1p and ALP 129.0 0 0 0 0 0.6189399232920106 P53903 40.167084645925115 35.0 0.0 no 11863 chrXIV_349675r 30523 essential YNL149C 59 + CTACAAGCACTTTATAAGAT Y|21|* silent|TAC>TAT|Y|21 PGA2 Processing of Gas1p and ALP 129.0 0 0 0 0 -1.1815826435492176 P53903 37.357385942043656 30.0 0.0 no 11864 chrXIV_362126r 30526 high_effect YNL139C 3569 + CCATTTGAAAGCGCGTTTGA H|1191|D H|1191|Y THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 0.5284021266896132 P53552 0.0 0.0 46.882813085410355 45.0 0.0 no 11865 chrXIV_362126 30527 high_effect YNL139C 3572 - CCTTCAAACGCGCTTTCAAA K|1197|N silent|AAG>AAA|K|1197 L|1196|F silent|TTG>TTA|L|1196 THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 0.7789589466269591 P53552 0.0 0.0 45.992753390765934 45.0 0.0 no 11866 chrXIV_362149r 30529 high_effect YNL139C 3546 + CTACCAAGCAGCGCATTGAT P|1184|A P|1184|S P|1184|R P|1184|L THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 -0.9303880104364678 P53552 0.0 0.0 0.0 0.0 50.600211817327484 50.0 0.0 no 11867 chrXIV_362446r 30530 high_effect YNL139C 3249 + AGCTCTGAAGCAGGCAATTT S|1084|R silent|AGC>AGT|S|1084 S|1085|C S|1085|F THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 0.17919615974931702 P53552 0.570387601852417 0.047644585371017456 0.2889933586120605 48.74568784831229 45.0 0.0 no 11868 chrXIV_362744 30534 high_effect YNL139C 2954 - CCTTGATTTGATTCTGAATC K|991|N silent|AAG>AAA|K|991 THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 0.123710465758279 P53552 0.0 41.80002020960217 35.0 0.0 no 11869 chrXIV_362744r 30535 high_effect YNL139C 2951 + CCTGATTCAGAATCAAATCA L|985|V silent|CTG>TTG|L|985 THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 -0.05879392605812295 P53552 0.7269423007965088 40.17439493891169 35.0 0.0 no 11870 chrXIV_362803r 30538 high_effect YNL139C 2892 + GAGCGTAAGAATGCACTATC R|966|G R|966|C THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 -0.6202341720736506 P53552 0.3437245786190033 0.06129361689090729 43.25416140243078 45.0 0.0 no 11871 chrXIV_362984 30539 high_effect YNL139C 2714 - CCAAGTAGTCTCTCCATATG L|911|F silent|TTG>TTA|L|911 THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 -0.0886201380976922 P53552 0.3286913931369781 48.81508281607813 45.0 0.0 no 11872 chrXIV_363129 30541 high_effect YNL139C 2569 - ATTCATTTCATCGCATCTAG M|862|I M|862|I THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 -0.15207917124551673 P53552 0.05407468229532242 0.05407468229532242 44.058940779626596 35.0 0.0 no 11873 chrXIV_363331r 30543 high_effect YNL139C 2364 + CAACTATTAATGTTAAACTC L|790|V silent|CTA>TTA|L|790 THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 0.9221505666166948 P53552 0.0 32.067491575801284 25.0 0.0 no 11874 chrXIV_363503r 30544 high_effect YNL139C 2192 + ATCAATATTTATTGCAGGTT S|732|* S|732|L THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 -0.16136975447088986 P53552 0.10406444221735 39.737915919986456 25.0 0.0 no 11875 chrXIV_363929r 30550 high_effect YNL139C 1766 + GAACAATCCAATTGCCACAT N|590|K silent|AAC>AAT|N|590 THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 0.22029642377757394 P53552 0.6377283334732056 44.57786761720529 40.0 0.0 no 11876 chrXIV_364216 30556 high_effect YNL139C 1482 - TTCAATTCAAGGGATTCAAA L|500|F silent|TTG>TTA|L|500 THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 0.20554480642226766 P53552 0.14817152917385099 37.24370149716765 30.0 0.0 no 11877 chrXIV_364326 30559 high_effect YNL139C 1372 - ATCTTTTGATTCACCAGATG D|464|H D|464|N THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 -0.15326101203731535 P53552 0.14706489443778992 0.5455925464630127 43.40678187836147 35.0 0.0 no 11878 chrXIV_364339r 30560 high_effect YNL139C 1356 + TACACATCAATGACCTCATC Y|453|* silent|TAC>TAT|Y|453 T|454|R T|454|I THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 -0.3934904455555757 P53552 0.4643248319625855 0.1502128690481186 43.565519899500195 40.0 0.0 no 11879 chrXIV_364389 30561 high_effect YNL139C 1309 - TCTTCCCAAATATCTAGATA R|443|T R|443|K G|442|A G|442|E THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 -0.3410520643115645 P53552 0.0 0.0 1.0 0.4460555613040924 41.694080094701405 30.0 0.0 no 11880 chrXIV_364414 30562 high_effect YNL139C 1284 - TCACTAACATATAACACTTT S|434|T S|434|N E|435|Q E|435|K THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 0.11181823391288986 P53552 0.06044342741370201 0.07472648471593857 0.08299417793750763 0.09313160181045532 35.70706456334228 25.0 0.0 no 11881 chrXIV_364441 30563 high_effect YNL139C 1257 - TGCTTTAACACATGTATCAC K|425|N silent|AAG>AAA|K|425 THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 0.5403669068248874 P53552 0.28841379284858704 41.331215250936786 35.0 0.0 no 11882 chrXIV_364510r 30565 high_effect YNL139C 1185 + CAGCAAGATATTTTATTATT Q|397|E Q|397|* THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 0.21639581158704446 P53552 1.0 34.932947754715144 20.0 0.0 no 11883 chrXIV_364598 30566 high_effect YNL139C 1100 - TAACATCATCATTTACAACA V|373|L V|373|I D|372|H D|372|N THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 0.19008218922391001 P53552 0.3328016996383667 0.216527059674263 0.06374834477901459 0.20770128071308136 35.81800418062818 25.0 0.0 no 11884 chrXIV_364599 30567 high_effect YNL139C 1099 - AACATCATCATTTACAACAA V|373|L V|373|I D|372|H D|372|N THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 0.6612909829471837 P53552 0.3328016996383667 0.216527059674263 0.06374834477901459 0.20770128071308136 35.120796880655014 25.0 0.0 no 11885 chrXIV_364735 30569 high_effect YNL139C 963 - TCTTGTAGAAATTCCATCTC E|328|Q E|328|K THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 0.4741945359743612 P53552 0.3204514682292938 0.5814254283905029 42.59358646500164 35.0 0.0 no 11886 chrXIV_365005r 30572 high_effect YNL139C 690 + TCTAGTCAGTTTATCACTGA S|231|C S|231|F Q|233|E Q|233|* THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 0.38949599885364494 P53552 0.0 0.0 1.0 44.68814277865471 35.0 0.0 no 11887 chrXIV_365097 30573 high_effect YNL139C 601 - TTTCAAATATGCGGACACTT L|206|F silent|TTG>TTA|L|206 THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 0.31657586597631104 P53552 0.12809856235980988 41.42718705391378 35.0 0.0 no 11888 chrXIV_365177 30576 high_effect YNL139C 521 - CCACTGAATTTTCTACCAAA V|180|L V|180|M silent|GTG>GTC|V|180 silent|GTG>GTA|V|180 THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 0.3102876477886423 P53552 0.12499506026506425 0.032806895673274994 42.144856533613 35.0 0.0 no 11889 chrXIV_365192r 30578 high_effect YNL139C 503 + ACTGAAGAAATATAACCTTT L|169|V silent|CTG>TTG|L|169 THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 0.4719062439900028 P53552 0.27054303884506226 34.388178194279426 25.0 0.0 no 11890 chrXIV_365299 30580 high_effect YNL139C 399 - AACAATTCTTCATGCAACGA L|139|F silent|TTG>TTA|L|139 THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 0.18842356105747665 P53552 0.07050155848264694 40.26133323529899 35.0 0.0 no 11891 chrXIV_365456 30581 high_effect YNL139C 242 - ATGCAACATCAGAAAGCTTG A|87|P A|87|T V|86|L V|86|I THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 -0.5156312233142577 P53552 0.045204926282167435 0.05894357338547706 0.2769589126110077 1.0 40.89683417260221 40.0 0.0 no 11892 chrXIV_365457 30582 high_effect YNL139C 241 - TGCAACATCAGAAAGCTTGA A|87|P A|87|T V|86|L V|86|I THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 -0.10704797403069466 P53552 0.045204926282167435 0.05894357338547706 0.2769589126110077 1.0 42.052350623492366 40.0 0.0 no 11893 chrXIV_365564r 30586 high_effect YNL139C 131 + CTGCTCCGATTTCACTGCAC C|45|W silent|TGC>TGT|C|45 S|46|C S|46|F THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 0 0 0 0.4553255976644213 P53552 0.16827158629894254 0.05206913501024246 0.06206602230668067 54.15509746230993 55.00000000000001 0.0 no 11894 chrXIV_365642r 30589 high_effect YNL139C 53 + ACCACCAGCTTCCCCTAGTC P|19|R P|19|L P|19|A P|19|S THO2 suppressor of the Transcriptional defect of Hpr1 by Overexpression 1597.0 0 1 0 0 0.2111431334343239 P53552 0.5462045073509216 0.35156288743019104 0.7957050800323486 0.8439947366714478 63.5896314289883 60.0 0.0 no 11895 chrXIV_366283 30591 essential YNL138W-A 128 + ACAAGGCCACTCCGCATCTT Q|44|E Q|44|* silent|GGC>GGG|G|45 silent|GGC>GGT|G|45 0 0 0 0 0.3946732574054623 P0C074 0.05070739239454269 56.49479334007657 55.00000000000001 1.0 no 11896 chrXIV_366331r 30592 essential YNL138W-A 179 - TACGAGTGTCACGTATACTA R|66|P R|66|H 0 0 0 0 -2.1716202694830637 P0C074 0.003048373386263848 0.003394318046048284 43.766527717525435 40.0 1.0 yes 11897 chrXIV_369039 30595 essential YNL137C 997 - TCCAGATCTTAAAGCGGATT G|339|R G|339|R G|339|A G|339|E 0 0 0 0 -0.4202893183372114 P27929 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.5347785353660583 0.5347785353660583 0.7734475135803223 1.0 44.89232306148591 40.0 0.0 no 11898 chrXIV_369064r 30597 essential YNL137C 969 + ACAAAAAAAGAATTATCTGA T|324|R T|324|I 0 0 0 0 -0.7336140433022261 P27929 0.9476869702339172 0.9472420215606691 0.5277756452560425 0.19738714396953586 27.88625953822492 20.0 0.0 no 11899 chrXIV_369115 30599 essential YNL137C 921 - GCCAGTGAAATCAACTCGTC silent|CTG>CTC|L|313 silent|CTG>CTA|L|313 A|314|P A|314|T 0 0 0 0 -2.303602715816377 P27929 0.9573720097541808 0.9523990154266356 0.3019787073135376 0.6209197044372559 47.44042399335103 50.0 0.0 yes 11900 chrXIV_369209 30600 essential YNL137C 827 - TTTCTAACAACTGAGAGTCC E|282|Q E|282|K 0 0 0 0 -1.090792125955982 P27929 0.956179976463318 0.9475290179252625 0.5891243815422058 0.9030583500862122 42.84626502601179 40.0 0.0 no 11901 chrXIV_369244r 30603 essential YNL137C 789 + TCGATAGATGAACTCAAACA S|264|W S|264|L 0 0 0 0 -0.2450780879272316 P27929 0.9288619756698608 0.9298099875450134 0.15569207072257996 0.711231529712677 36.98654935961514 35.0 0.0 no 11902 chrXIV_369343r 30606 essential YNL137C 690 + CAGCAATATAACGCATTAAA Q|232|E Q|232|* 0 0 0 0 1.2406331908961352 P27929 0.9590039849281312 1.0 35.884899413917594 30.0 0.0 no 11903 chrXIV_369344r 30607 essential YNL137C 689 + ACAGCAATATAACGCATTAA Q|231|E Q|231|* Q|232|E Q|232|* 0 0 0 0 -0.7868562419104939 P27929 0.9590039849281312 0.9590039849281312 0.9570892453193665 1.0 37.43733236871872 30.0 0.0 no 11904 chrXIV_369457 30608 essential YNL137C 579 - TTCTTCTCCCAAACTTCCTT K|199|N silent|AAG>AAA|K|199 E|198|D silent|GAG>GAA|E|198 0 0 0 0 -0.03823144483966415 P27929 0.9355990290641784 0.94931298494339 0.3891960382461548 0.5163972973823547 51.63836029626856 40.0 0.0 no 11905 chrXIV_369546 30610 essential YNL137C 490 - TTCTTGGAAACTTGGTTTCT E|170|Q E|170|K 0 0 0 0 1.1132322007637276 P27929 0.956179976463318 0.9475290179252625 0.2798698842525482 0.6419607400894165 43.856289204593736 35.0 0.0 no 11906 chrXIV_369581r 30612 essential YNL137C 452 + TGTCAAACCGGACAAAGTGC silent|GTC>GTG|V|152 silent|GTC>GTT|V|152 0 0 0 0 1.4634016856383059 P27929 45.02916111338823 50.0 0.0 no 11907 chrXIV_369723r 30616 essential YNL137C 310 + GGCTTGATTTTGCCCTTTTC L|105|V L|105|F 0 0 0 0 0.40327130179071546 P27929 0.9512209892272948 0.9587849974632264 0.0 0.0 54.523678635130864 45.0 0.0 no 11908 chrXIV_369861r 30618 essential YNL137C 172 + AACATTTGACAGAAAAGAGA H|59|D H|59|Y 0 0 0 0 0.8818385861607445 P27929 0.9473130106925964 0.9489949941635132 0.03953709080815315 0.01734383963048458 33.143904358951715 30.0 0.0 no 11909 chrXIV_369918r 30620 essential YNL137C 115 + AATCTTTGTATCAACAGAAG S|40|C S|40|F 0 0 0 0 0.2816408624293327 P27929 0.945252001285553 0.9294660091400146 0.009840371087193487 0.005224833730608225 35.43639719081949 30.0 0.0 no 11910 chrXIV_370022r 30622 essential YNL137C 11 + GGCTAATTTGCTAAAATCTT A|5|G A|5|V 0 0 0 0 0.5886099094847184 P27929 0.9484469890594482 0.9504740238189696 0.017709534615278244 1.0 39.20682097353887 30.0 0.0 no 11911 chrXIV_375388 30625 essential YNL132W 67 + GGTCCATATTTGTCATCGTT S|24|C S|24|F silent|TCC>TCG|S|24 silent|TCC>TCT|S|24 KRE33 Killer toxin REsistant 1056.0 0 0 0 0 0.4501031278263897 P53914 0.945252001285553 0.9294660091400146 0.0054736691527068615 0.0021815993823111053 50.333764669384955 40.0 1.0 no 11912 chrXIV_375464r 30626 essential YNL132W 146 - AGACGGACTTGTTCATCTTA V|55|L V|55|I KRE33 Killer toxin REsistant 1056.0 0 0 0 0 0.9666211031247801 P53914 0.9539830088615416 0.9574310183525084 0.0 0.0 45.931262197212675 40.0 1.0 no 11913 chrXIV_375732 30628 essential YNL132W 411 + ACCATTGAAACTGTAGAAGG silent|ACC>ACG|T|138 silent|ACC>ACT|T|138 T|138|S T|138|I KRE33 Killer toxin REsistant 1056.0 0 0 0 0 -0.3283441822124525 P53914 0.9491789937019348 0.9472420215606691 0.06220458075404167 0.0014860876835882664 39.96173970890902 40.0 1.0 no 11914 chrXIV_375733r 30629 essential YNL132W 415 - ACCACCTTCTACAGTTTCAA G|145|R G|145|S G|145|A G|145|D KRE33 Killer toxin REsistant 1056.0 0 0 0 0 0.6012795422687949 P53914 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 49.11535499329659 40.0 1.0 no 11915 chrXIV_375808r 30630 essential YNL132W 490 - GGCGTGAACATCCATAGTCA A|170|P A|170|T KRE33 Killer toxin REsistant 1056.0 0 0 0 0 0.45646566918604603 P53914 0.9573720097541808 0.9523990154266356 0.019775286316871643 0.14099201560020447 50.85638701952946 50.0 1.0 no 11916 chrXIV_375824 30631 essential YNL132W 503 + TCACGCCCGTTATCGTACTG H|169|Q silent|CAC>CAT|H|169 H|169|D H|169|Y KRE33 Killer toxin REsistant 1056.0 0 0 0 0 0.9931208534831794 P53914 0.9588389992713928 0.9473130106925964 0.9489949941635132 0.0 0.0 0.0 53.73521452704267 55.00000000000001 1.0 no 11917 chrXIV_375906r 30632 essential YNL132W 588 - TCATCAACGACTAAACAGTT D|203|H D|203|N D|202|H D|202|N KRE33 Killer toxin REsistant 1056.0 0 0 0 0 0.29351155733975864 P53914 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.0014598398702219126 0.0048855370841920384 0.002932908944785595 0.07820861041545868 38.82811365532905 35.0 1.0 no 11918 chrXIV_375945r 30633 essential YNL132W 627 - ACGTTTTTGGCACCAGATAG V|216|L V|216|M KRE33 Killer toxin REsistant 1056.0 0 0 0 0 -1.9578689703022727 P53914 0.9539830088615416 0.9587630033493042 0.21926888823509216 0.05783022940158844 48.1579321890269 45.0 1.0 no 11919 chrXIV_375981r 30635 essential YNL132W 663 - GGCAATTCGTCATCTTCCTT L|227|F silent|TTG>TTA|L|227 KRE33 Killer toxin REsistant 1056.0 0 0 0 0 -0.974129542628565 P53914 0.9587849974632264 0.050251327455043786 52.45160022717886 45.0 1.0 no 11920 chrXIV_376005r 30636 essential YNL132W 687 - TCTTGCAACTCTAATTGCTT E|236|Q E|236|K L|234|F silent|TTG>TTA|L|234 KRE33 Killer toxin REsistant 1056.0 0 0 0 0 0.42591493011592907 P53914 0.956179976463318 0.9475290179252625 0.9587849974632264 0.16537925601005554 0.2045581191778183 0.016761628910899162 44.704199894006756 35.0 1.0 no 11921 chrXIV_376039r 30637 essential YNL132W 721 - AGCTGGTTGGACATCTTCTA A|247|P A|247|T KRE33 Killer toxin REsistant 1056.0 0 0 0 0 -0.16526415889392224 P53914 0.9573720097541808 0.9523990154266356 0.011600113473832607 0.07460848242044449 51.10209976818175 45.0 1.0 no 11922 chrXIV_376052r 30639 essential YNL132W 734 - AAACCAATGAACCAGCTGGT V|251|L V|251|I L|250|F silent|TTG>TTA|L|250 KRE33 Killer toxin REsistant 1056.0 0 0 0 0 -0.2724251606024025 P53914 0.9539830088615416 0.9574310183525084 0.9587849974632264 0.2817742228507996 0.5644755363464355 0.013769089244306087 45.8494893880636 45.0 1.0 no 11923 chrXIV_376112 30640 essential YNL132W 791 + TTCTTTCATTGATGCCATTT S|265|C S|265|F F|266|L silent|TTC>TTT|F|266 KRE33 Killer toxin REsistant 1056.0 0 0 0 0 0.4023605343212867 P53914 0.945252001285553 0.9294660091400146 0.9387490153312684 0.028667906299233437 0.027198798954486847 0.19045059382915494 45.91863991815444 30.0 1.0 no 11924 chrXIV_376213r 30642 essential YNL132W 895 - ATACCCGTGAGAAACGGCCG silent|GGG>GGC|G|304 silent|GGG>GGA|G|304 G|304|A G|304|E KRE33 Killer toxin REsistant 1056.0 0 0 0 0 -1.1690230738480325 P53914 0.9499930143356324 0.9438679814338684 0.011526653543114662 0.006535317283123732 51.479910999512704 60.0 1.0 no 11925 chrXIV_376257r 30643 essential YNL132W 939 - GTCTTTAAATTTTCGGGAGA K|319|N silent|AAG>AAA|K|319 KRE33 Killer toxin REsistant 1056.0 0 0 0 0 -0.5742525431948744 P53914 0.9355990290641784 0.3125852048397064 41.76317936495411 35.0 1.0 no 11926 chrXIV_376322r 30644 essential YNL132W 1004 - TATCATAATCAATGTGTTCT D|341|H D|341|N KRE33 Killer toxin REsistant 1056.0 0 0 0 0 0.2531394207350821 P53914 0.9486550092697144 0.956179976463318 0.04918178543448448 0.4057512581348419 37.567847866080506 25.0 1.0 no 11927 chrXIV_376434 30645 essential YNL132W 1113 + CCTCAAGACCATCAAGTTCT Q|373|E Q|373|* P|372|R P|372|L KRE33 Killer toxin REsistant 1056.0 0 0 0 0 0.18992942738976173 P53914 0.9590039849281312 0.9432820081710817 0.9430609941482544 0.6370764374732971 0.0016665534349158404 0.002233124105259776 48.92397434155232 45.0 1.0 no 11928 chrXIV_376433 30646 essential YNL132W 1112 + TCCTCAAGACCATCAAGTTC P|372|R P|372|L P|372|A P|372|S KRE33 Killer toxin REsistant 1056.0 0 0 0 0 -0.14201053557643706 P53914 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0016665534349158404 0.002233124105259776 0.054719045758247375 0.009781363420188429 48.168934060404865 45.0 1.0 no 11929 chrXIV_376503 30649 essential YNL132W 1182 + CCAATCGTCAAGAACTTGCT P|395|R P|395|L I|396|M silent|ATC>ATT|I|396 KRE33 Killer toxin REsistant 1056.0 0 0 0 0 0.5986091955897046 P53914 0.9432820081710817 0.9430609941482544 0.9598389863967896 0.09500677138566972 0.03666171431541443 0.01640212908387184 46.00400674809293 45.0 1.0 no 11930 chrXIV_376523 30652 essential YNL132W 1202 + GGGCCCATATCTAGTCTTCA silent|GGC>GGG|G|402 silent|GGC>GGT|G|402 P|403|A P|403|S KRE33 Killer toxin REsistant 1056.0 0 0 0 0 0.5218602319451677 P53914 0.9562489986419678 0.9498909711837769 0.011438596062362194 0.017335046082735058 56.990335789133844 50.0 1.0 no 11931 chrXIV_376539 30654 essential YNL132W 1218 + TTCATGGCATCCACTATCAA F|407|L silent|TTC>TTT|F|407 KRE33 Killer toxin REsistant 1056.0 0 0 0 0 0.6112714670979909 P53914 0.9387490153312684 0.1816706657409668 47.73822080994114 40.0 1.0 no 11932 chrXIV_376549r 30655 essential YNL132W 1231 - ACCTTCGTAACCATTGATAG G|417|R G|417|S G|417|A G|417|D KRE33 Killer toxin REsistant 1056.0 0 0 0 0 -1.7831173950704202 P53914 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 44.81700171710099 40.0 1.0 no 11933 chrXIV_376615 30658 essential YNL132W 1294 + ATCAAAACAACACATCCGGT Q|433|E Q|433|* KRE33 Killer toxin REsistant 1056.0 0 0 0 0 0.3888529587486703 P53914 0.9590039849281312 0.2922478914260864 42.01372854179402 40.0 1.0 no 11934 chrXIV_376616 30659 essential YNL132W 1295 + TCAAAACAACACATCCGGTC Q|433|E Q|433|* N|434|K silent|AAC>AAT|N|434 KRE33 Killer toxin REsistant 1056.0 0 0 0 0 -1.144266778534636 P53914 0.9590039849281312 0.9439849853515624 0.2922478914260864 0.3582996129989624 42.860862472844474 45.0 1.0 no 11935 chrXIV_376709 30660 essential YNL132W 1388 + TCAATTACGTGAAATTTCCT Q|464|E Q|464|* KRE33 Killer toxin REsistant 1056.0 0 0 0 0 0.4364782903664484 P53914 0.9590039849281312 0.6085056066513062 39.609796456822096 30.0 1.0 no 11936 chrXIV_376734 30661 essential YNL132W 1413 + GAACCAATCAGATATGCTCC P|473|A P|473|S P|473|R P|473|L KRE33 Killer toxin REsistant 1056.0 0 0 0 0 -0.2241938225718228 P53914 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.02817441336810589 0.4464336931705475 0.0029303578194230795 0.0033482688013464212 46.22089166006464 45.0 1.0 no 11937 chrXIV_376818r 30663 essential YNL132W 1500 - GTTCCTCTTGTTGCAAATCT G|506|A G|506|E G|506|R G|506|R KRE33 Killer toxin REsistant 1056.0 0 0 0 0 0.4561202943353582 P53914 0.9499930143356324 0.9438679814338684 0.941340982913971 0.941340982913971 0.09924060851335527 0.014393876306712627 0.1411609947681427 0.1411609947681427 49.40115601397622 40.0 1.0 no 11938 chrXIV_376901 30665 essential YNL132W 1580 + TCCTGTCTCAGAAAATTTCC P|528|R P|528|L P|528|A P|528|S KRE33 Killer toxin REsistant 1056.0 0 0 0 0 -0.07539377636050823 P53914 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.3733926713466644 0.18473881483078006 0.4994221329689026 0.474200427532196 45.534852314732454 40.0 1.0 no 11939 chrXIV_377025r 30669 essential YNL132W 1707 - CCATCCTTTGGATCAATTGG G|576|R G|576|S D|575|H D|575|N KRE33 Killer toxin REsistant 1056.0 0 0 0 0 -1.3438571881976082 P53914 0.941340982913971 0.951104998588562 0.9486550092697144 0.956179976463318 0.5497767925262451 0.7739768624305725 0.020599637180566788 0.30398061871528625 48.42470493931967 45.0 1.0 no 11940 chrXIV_377028 30670 essential YNL132W 1707 + CCAATTGATCCAAAGGATGG P|570|R P|570|L KRE33 Killer toxin REsistant 1056.0 0 0 0 0 -0.5654015359870397 P53914 0.9432820081710817 0.9430609941482544 0.0030817980878055096 0.002540800953283906 43.57334879652876 45.0 1.0 no 11941 chrXIV_376853r 30671 essential YNL132W 1535 - TGACAACAAATAGATTACAT V|518|L V|518|I V|517|L V|517|I KRE33 Killer toxin REsistant 1056.0 0 0 0 0 -1.7297681059578314 P53914 0.9539830088615416 0.9574310183525084 0.9539830088615416 0.9574310183525084 0.010184097103774548 0.14472542703151706 0.2254170477390289 0.1635540872812271 32.574127131315954 25.0 1.0 no 11942 chrXIV_377241 30677 essential YNL132W 1920 + AATCCTGAATACGCATCCAT P|642|A P|642|S P|642|R P|642|L KRE33 Killer toxin REsistant 1056.0 0 0 0 0 0.2794735160604849 P53914 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.009246181696653366 0.00560555187985301 0.003095782129094005 0.002558261388912797 46.09531827212771 40.0 1.0 no 11943 chrXIV_377286 30679 essential YNL132W 1965 + TTACTGAGAGACTATTTCGA L|657|V silent|CTG>TTG|L|657 KRE33 Killer toxin REsistant 1056.0 0 0 0 0 1.0100653665843773 P53914 0.9512209892272948 0.0069330837577581406 40.57259066461137 35.0 1.0 no 11944 chrXIV_377340r 30681 essential YNL132W 2022 - CTCTTTATAGAATAATCCTT K|680|N silent|AAG>AAA|K|680 KRE33 Killer toxin REsistant 1056.0 0 0 0 0 -0.4741737713365704 P53914 0.9355990290641784 0.5223760008811951 37.88461109576304 25.0 1.0 no 11945 chrXIV_377469 30683 essential YNL132W 2148 + CCTCATTATCTACATTATTT H|718|D H|718|Y P|717|R P|717|L KRE33 Killer toxin REsistant 1056.0 0 0 0 0 0.6872325077198467 P53914 0.9473130106925964 0.9489949941635132 0.9432820081710817 0.9430609941482544 0.11597535759210588 0.008533080108463764 0.0032295996788889174 0.004831184633076191 41.04099345669573 25.0 1.0 no 11946 chrXIV_377469r 30684 essential YNL132W 2151 - CCCAAATAATGTAGATAATG L|723|F silent|TTG>TTA|L|723 G|724|R G|724|S KRE33 Killer toxin REsistant 1056.0 0 0 0 0 0.7843648055221042 P53914 0.9587849974632264 0.941340982913971 0.951104998588562 0.053628329187631614 0.0 0.0 35.374882299864346 30.0 1.0 no 11947 chrXIV_377509 30685 essential YNL132W 2188 + CGCAATCGTTGCATAAATTC Q|731|E Q|731|* S|732|W S|732|L KRE33 Killer toxin REsistant 1056.0 0 0 0 0 -0.3758956213965979 P53914 0.9590039849281312 0.9288619756698608 0.9298099875450134 1.0 0.016348730772733692 0.2956254482269287 41.77141274764762 40.0 1.0 no 11948 chrXIV_377569r 30687 essential YNL132W 2251 - TTCACCAGTTAAATCGTTTG E|757|Q E|757|K G|756|A G|756|D KRE33 Killer toxin REsistant 1056.0 0 0 0 0 0.05411863494661702 P53914 0.956179976463318 0.9475290179252625 0.9499930143356324 0.9446240067481996 0.0 0.0 0.04690220206975937 0.00192695832811296 41.962802482699374 35.0 1.0 no 11949 chrXIV_378814 30688 essential YNL131W 47 + ACCACAATTTTCCAGAAATC P|17|R P|17|L P|17|A P|17|S TOM22 Translocase of the Outer Mitochondrial membrane 152.0 0 1 0 0 0.1229498544444342 P49334 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.3769216537475586 0.22170470654964447 0.473431259393692 0.5636765956878662 41.421094531721735 35.0 1.0 no 11950 chrXIV_379073 30691 essential YNL131W 306 + ACCACCACTGCTTTGTTACT silent|ACC>ACG|T|103 silent|ACC>ACT|T|103 T|103|S T|103|I TOM22 Translocase of the Outer Mitochondrial membrane 152.0 0 0 0 0 -0.040348149746565726 P49334 0.9491789937019348 0.9472420215606691 0.338278204202652 0.008635341189801693 53.173137969806824 45.0 1.0 no 11951 chrXIV_387272r 30694 essential YNL126W 48 - TGACTCTGCGACAATAATTG S|22|T S|22|N Q|21|H silent|CAG>CAA|Q|21 SPC98 Spindle Pole Component 846.0 0 0 0 0 0.5842738450048173 P53540 0.9512869715690612 0.9536849856376648 0.9570760130882264 0.9010613560676576 0.5372216701507568 0.03714364767074585 40.31835535174707 40.0 1.0 no 11952 chrXIV_387328 30695 essential YNL126W 101 + ACTGCGATCATCCACCAAAT L|35|V silent|CTG>TTG|L|35 R|36|G R|36|* SPC98 Spindle Pole Component 846.0 0 0 0 0 -0.8641559259927958 P53540 0.9512209892272948 0.8994590044021606 0.050797216594219215 0.3795339465141296 48.186837361945884 45.0 1.0 no 11953 chrXIV_387341 30696 essential YNL126W 114 + ACCAAATCGGCAACTCAATT silent|ACC>ACG|T|39 silent|ACC>ACT|T|39 T|39|S T|39|I SPC98 Spindle Pole Component 846.0 0 0 0 0 1.0852821352550035 P53540 0.9491789937019348 0.9472420215606691 0.8370003700256348 0.08056450635194777 43.296515779771774 40.0 1.0 no 11954 chrXIV_387463r 30699 essential YNL126W 239 - TTACCATATCATCGGTGTTC V|86|L V|86|I M|85|I M|85|I SPC98 Spindle Pole Component 846.0 0 0 0 0 0.3391843271256514 P53540 0.9539830088615416 0.9574310183525084 0.9553959965705872 0.9553959965705872 0.4824056029319763 0.3298394680023193 1.0 1.0 47.24317747836256 40.0 1.0 no 11955 chrXIV_387585 30700 essential YNL126W 358 + AACATTTACTTAGCCCAGTG H|121|D H|121|Y SPC98 Spindle Pole Component 846.0 0 1 0 0 -0.11738385924116347 P53540 0.9473130106925964 0.9489949941635132 0.9677202701568604 0.12778499722480774 46.66867257457182 40.0 1.0 no 11956 chrXIV_387699r 30703 essential YNL126W 475 - AACAGAACTGTAGGTTGAAG V|165|L V|165|I SPC98 Spindle Pole Component 846.0 0 0 0 0 -1.2602068778000728 P53540 0.9539830088615416 0.9574310183525084 0.5277289152145386 0.5407682657241821 38.51028653254184 40.0 1.0 no 11957 chrXIV_387796 30705 essential YNL126W 569 + TACATTATTAGCTACGACAT T|191|R T|191|I SPC98 Spindle Pole Component 846.0 0 0 0 0 0.5774279258878149 P53540 0.9476869702339172 0.9472420215606691 0.0 0.0 39.58703113130253 30.0 1.0 no 11958 chrXIV_387854r 30706 essential YNL126W 630 - TCAAAATTGGGTATCTTAGA E|217|Q E|217|K SPC98 Spindle Pole Component 846.0 0 0 0 0 -1.65861327401523 P53540 0.956179976463318 0.9475290179252625 0.1887781023979187 0.1829051673412323 37.82871492856055 30.0 1.0 no 11959 chrXIV_388018 30708 essential YNL126W 791 + CACAGCATTTGTGAACAATC T|265|R T|265|I A|266|G A|266|V SPC98 Spindle Pole Component 846.0 0 0 0 0 0.060944800212343275 P53540 0.9476869702339172 0.9472420215606691 0.9484469890594482 0.9504740238189696 0.010495327413082123 0.011368207633495329 1.0 0.14160625636577606 41.33073184983243 40.0 1.0 no 11960 chrXIV_388188r 30710 essential YNL126W 964 - TCTTATAGTAAGATCTCCGT R|328|T R|328|K SPC98 Spindle Pole Component 846.0 0 0 0 0 -0.3267777875403369 P53540 0.932735025882721 0.955805003643036 0.056083697825670235 0.6253007650375366 44.333204402804434 35.0 1.0 no 11961 chrXIV_388283 30712 essential YNL126W 1056 + GGTCTACTCCGAGCTACTTA L|354|V silent|CTA>TTA|L|354 L|355|V L|355|F SPC98 Spindle Pole Component 846.0 0 0 0 0 0.438108733252064 P53540 0.9512209892272948 0.9512209892272948 0.9587849974632264 0.05622109770774841 0.3680476248264313 0.04057555645704269 53.18627452705322 50.0 1.0 no 11962 chrXIV_388319 30713 essential YNL126W 1092 + GCTGAAAACACTGATACAAA A|365|G A|365|V SPC98 Spindle Pole Component 846.0 0 0 0 0 0.7100409478679607 P53540 0.9484469890594482 0.9504740238189696 0.35145023465156555 0.2693763077259064 35.84016749776646 35.0 1.0 no 11963 chrXIV_388378 30714 essential YNL126W 1151 + GTTCAACCAAGAAAGAGTTC F|385|L silent|TTC>TTT|F|385 N|386|K silent|AAC>AAT|N|386 SPC98 Spindle Pole Component 846.0 0 0 0 0 0.3111581643992037 P53540 0.9387490153312684 0.9439849853515624 1.0 0.5154836177825928 40.26557900081099 40.0 1.0 no 11964 chrXIV_388459r 30717 essential YNL126W 1235 - CCTCTTTACAGTACTTTTCT E|418|Q E|418|K E|418|D silent|GAG>GAA|E|418 SPC98 Spindle Pole Component 846.0 0 0 0 0 -2.020718823137092 P53540 0.956179976463318 0.9475290179252625 0.94931298494339 0.04847616329789162 0.03903992474079132 0.3615182042121887 47.505901293950565 35.0 1.0 yes 11965 chrXIV_387586 30718 essential YNL126W 359 + ACATTTACTTAGCCCAGTGC H|121|D H|121|Y SPC98 Spindle Pole Component 846.0 0 1 0 0 0.022771151598137446 P53540 0.9473130106925964 0.9489949941635132 0.9677202701568604 0.12778499722480774 52.053470585357616 45.0 1.0 no 11966 chrXIV_388522 30719 essential YNL126W 1295 + GTACCAGAGCAATTCTTATC Y|433|* silent|TAC>TAT|Y|433 Q|434|E Q|434|* SPC98 Spindle Pole Component 846.0 0 0 0 0 -2.3365046050962994 P53540 0.9590039849281312 0.9106955528259276 45.35484466155498 40.0 1.0 yes 11967 chrXIV_388747 30720 essential YNL126W 1520 + GCCAAATTATAAGTTAACAA P|508|R P|508|L P|508|A P|508|S SPC98 Spindle Pole Component 846.0 0 0 0 0 -0.3336657746610843 P53540 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.24690228700637815 0.16553202271461487 0.4669877886772156 0.8619905114173889 34.68989261520295 25.0 1.0 no 11968 chrXIV_388782r 30721 essential YNL126W 1558 - TCTTAAGGAAGAAAGCTGCA R|526|T R|526|K SPC98 Spindle Pole Component 846.0 0 0 0 0 -0.3501812357356535 P53540 0.932735025882721 0.955805003643036 0.18809817731380465 0.494674414396286 41.21395658535874 40.0 1.0 no 11969 chrXIV_388836 30722 essential YNL126W 1609 + TCATTAATGGATTGGATGCG silent|GTC>GTG|V|537 silent|GTC>GTT|V|537 SPC98 Spindle Pole Component 846.0 0 0 0 0 0.9839476215723656 P53540 42.16593103113229 40.0 1.0 no 11970 chrXIV_388925r 30724 essential YNL126W 1701 - ACGTTTAATACTAAACTCAA V|574|L V|574|I SPC98 Spindle Pole Component 846.0 0 0 0 0 -0.3855920282748307 P53540 0.9539830088615416 0.9574310183525084 0.0 0.0 34.02875505044761 25.0 1.0 no 11971 chrXIV_388944 30725 essential YNL126W 1717 + ACGTAAATCGTCCTTTTGGC N|573|K silent|AAC>AAT|N|573 SPC98 Spindle Pole Component 846.0 0 0 0 0 0.08950991782284383 P53540 0.9439849853515624 0.0 47.862508414452975 45.0 1.0 no 11972 chrXIV_389011 30726 essential YNL126W 1784 + GAACAATTATTTCTATCAAA N|596|K silent|AAC>AAT|N|596 SPC98 Spindle Pole Component 846.0 0 0 0 0 0.3101558362075238 P53540 0.9439849853515624 0.20165793597698206 31.716428169451603 20.0 1.0 no 11973 chrXIV_392900 30728 essential YNL124W 8 + TGACTTGTTTTCTAAGGCTT D|4|E silent|GAC>GAT|D|4 NAF1 Nuclear Assembly Factor 492.0 0 0 0 0 0.12827240701353387 P53919 0.9532920122146606 0.04380155727267265 45.20751272591792 35.0 1.0 no 11974 chrXIV_392933r 30730 essential YNL124W 44 - GCAATTCCACGTTCAAGTCC L|21|F silent|TTG>TTA|L|21 E|20|Q E|20|K NAF1 Nuclear Assembly Factor 492.0 0 0 0 0 0.6715568580094045 P53919 0.9587849974632264 0.956179976463318 0.9475290179252625 0.3936684429645538 0.5133830308914185 0.8449146151542664 51.54484710225178 50.0 1.0 no 11975 chrXIV_392955r 30731 essential YNL124W 66 - CCTAAATCAACATCATCCTT G|29|R G|29|S NAF1 Nuclear Assembly Factor 492.0 0 0 0 0 0.4894547672064299 P53919 0.941340982913971 0.951104998588562 0.12798282504081726 0.6559382081031799 43.1195361242838 35.0 1.0 no 11976 chrXIV_392956r 30732 essential YNL124W 67 - ACCTAAATCAACATCATCCT G|29|R G|29|S G|29|A G|29|D NAF1 Nuclear Assembly Factor 492.0 0 0 0 0 0.4455307042929353 P53919 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.12798282504081726 0.6559382081031799 1.0 0.14359059929847715 43.293691866109675 35.0 1.0 no 11977 chrXIV_393010r 30733 essential YNL124W 121 - TGCGTCTGCTACCGGTTCAT A|47|P A|47|T D|46|H D|46|N NAF1 Nuclear Assembly Factor 492.0 0 0 0 0 0.07357771325342992 P53919 0.9573720097541808 0.9523990154266356 0.9486550092697144 0.956179976463318 0.25242534279823303 0.5107787251472473 0.15359456837177274 0.5720680356025696 57.19893727475489 55.00000000000001 1.0 no 11978 chrXIV_393063 30737 essential YNL124W 171 + TCTGAATCCGAATCAGATTC S|58|C S|58|F NAF1 Nuclear Assembly Factor 492.0 0 0 0 0 0.8915242968198125 P53919 0.945252001285553 0.9294660091400146 0.03660986199975014 0.032284677028656006 42.33695480871353 40.0 1.0 no 11979 chrXIV_393258r 30745 essential YNL124W 369 - TCATAATCTTCCGGTAGTTC E|130|Q E|130|K NAF1 Nuclear Assembly Factor 492.0 0 1 0 0 0.34147169838264063 P53919 0.956179976463318 0.9475290179252625 0.22721001505851746 0.08320502191781998 -0.6712340116500854 -0.2217960059642792 46.85513880547836 40.0 1.0 no 11980 chrXIV_393344 30746 essential YNL124W 452 + AATCATTCACGCCACGATGT I|152|M silent|ATC>ATT|I|152 NAF1 Nuclear Assembly Factor 492.0 0 0 0 0 -0.2731072685748311 P53919 0.9598389863967896 0.0 -1.1301720142364502 0.4716199934482575 -0.5866679549217224 48.13970904868154 45.0 1.0 no 11981 chrXIV_393355r 30748 essential YNL124W 466 - ACGCTTTTCGCCCGACATCG K|161|N silent|AAG>AAA|K|161 R|162|P R|162|H NAF1 Nuclear Assembly Factor 492.0 0 0 0 0 0.4082880889977633 P53919 0.9355990290641784 0.9099509716033936 0.9570810198783876 0.0415678434073925 0.0 0.0 -0.27805599570274353 0.03810599818825722 1.4669820070266724 -3.5141398906707764 -1.0744199752807615 55.541522636878035 60.0 1.0 no 11982 chrXIV_393405 30751 essential YNL124W 513 + CTCGAGGATAGAACTTTGAT silent|CTC>CTG|L|172 silent|CTC>CTT|L|172 NAF1 Nuclear Assembly Factor 492.0 0 0 0 0 0.2249517507249924 P53919 41.39577762161116 40.0 1.0 no 11983 chrXIV_393451r 30754 essential YNL124W 562 - TCTATAAAATGGGTTTTGCA R|194|T R|194|K NAF1 Nuclear Assembly Factor 492.0 0 0 0 0 -0.6671891466750599 P53919 0.932735025882721 0.955805003643036 0.0 0.0 2.8521618843078613 0.7277399897575378 2.9809169769287114 1.173285961151123 39.55017344341883 30.0 1.0 no 11984 chrXIV_393461r 30755 essential YNL124W 572 - GCAACTTAATTCTATAAAAT L|197|F silent|TTG>TTA|L|197 K|196|N silent|AAG>AAA|K|196 NAF1 Nuclear Assembly Factor 492.0 0 0 0 0 -0.2660539994850722 P53919 0.9587849974632264 0.9355990290641784 0.21658313274383545 0.31397926807403564 6.909148216247559 0.8259279727935791 5.686480045318604 0.14103800058364868 31.688181546317026 20.0 1.0 no 11985 chrXIV_393462r 30756 essential YNL124W 573 - GGCAACTTAATTCTATAAAA L|197|F silent|TTG>TTA|L|197 K|196|N silent|AAG>AAA|K|196 NAF1 Nuclear Assembly Factor 492.0 0 0 0 0 0.21727231554270016 P53919 0.9587849974632264 0.9355990290641784 0.21658313274383545 0.31397926807403564 6.909148216247559 0.8259279727935791 5.686480045318604 0.14103800058364868 33.87444555527605 25.0 1.0 no 11986 chrXIV_393559r 30759 essential YNL124W 670 - CTCGAAAGTATCTATCCAGT E|230|Q E|230|K NAF1 Nuclear Assembly Factor 492.0 0 0 0 0 0.3554834205219757 P53919 0.956179976463318 0.9475290179252625 0.0 0.0 44.422612908186295 40.0 1.0 no 11987 chrXIV_393560r 30760 essential YNL124W 671 - ACTCGAAAGTATCTATCCAG E|230|Q E|230|K E|230|D silent|GAG>GAA|E|230 NAF1 Nuclear Assembly Factor 492.0 0 0 0 0 0.23453888082384355 P53919 0.956179976463318 0.9475290179252625 0.94931298494339 0.0 0.0 0.0 42.39330096377051 40.0 1.0 no 11988 chrXIV_393725r 30762 essential YNL124W 836 - CACTATCGTTGGCTAGTTTG S|285|T S|285|N D|284|H D|284|N NAF1 Nuclear Assembly Factor 492.0 0 0 0 0 0.33011684088719795 P53919 0.9512869715690612 0.9536849856376648 0.9486550092697144 0.956179976463318 0.6347349286079407 0.5206494331359863 0.15494811534881592 0.5006170272827148 47.76677341312029 45.0 1.0 no 11989 chrXIV_393737 30763 essential YNL124W 845 + CAACGATAGTGACAATGTCA N|283|K silent|AAC>AAT|N|283 NAF1 Nuclear Assembly Factor 492.0 0 0 0 0 0.7855815431621463 P53919 0.9439849853515624 0.7928116917610168 40.40817346354846 40.0 1.0 no 11990 chrXIV_393794 30764 essential YNL124W 902 + ACCTAAACTGGTACCGCCGT P|302|R P|302|L P|302|A P|302|S NAF1 Nuclear Assembly Factor 492.0 0 0 0 0 0.6401501139262976 P53919 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.5021846890449524 0.3006067276000977 0.9657763242721558 0.7120099663734436 53.95503330066259 55.00000000000001 1.0 no 11991 chrXIV_393795r 30766 essential YNL124W 906 - CCCAACGGCGGTACCAGTTT L|308|F silent|TTG>TTA|L|308 G|309|R G|309|S NAF1 Nuclear Assembly Factor 492.0 0 0 0 0 0.3846553298688829 P53919 0.9587849974632264 0.941340982913971 0.951104998588562 0.7000190615653992 0.2537356019020081 0.7547991275787354 57.393422047413985 60.0 1.0 no 11992 chrXIV_393807r 30767 essential YNL124W 918 - TTACTGCTCATGCCCAACGG S|312|T S|312|N S|311|T S|311|N NAF1 Nuclear Assembly Factor 492.0 0 0 0 0 0.3114024116582339 P53919 0.9512869715690612 0.9536849856376648 0.9512869715690612 0.9536849856376648 0.8769656419754028 0.4203947484493256 0.5876495242118835 0.5590514540672302 53.48221736266993 55.00000000000001 1.0 no 11993 chrXIV_393810r 30768 essential YNL124W 921 - GCATTACTGCTCATGCCCAA A|314|P A|314|T S|312|T S|312|N NAF1 Nuclear Assembly Factor 492.0 0 0 0 0 -0.5195243815275 P53919 0.9573720097541808 0.9523990154266356 0.9512869715690612 0.9536849856376648 0.14409707486629486 0.237520769238472 0.8769656419754028 0.4203947484493256 54.71906079757486 50.0 1.0 no 11994 chrXIV_393886 30769 essential YNL124W 994 + AATCCAGTGCTACCTCTAAT S|333|C S|333|F silent|TCC>TCG|S|333 silent|TCC>TCT|S|333 NAF1 Nuclear Assembly Factor 492.0 0 0 0 0 0.6873588438920105 P53919 0.945252001285553 0.9294660091400146 0.0754622370004654 0.1250210553407669 48.129884860569064 40.0 1.0 no 11995 chrXIV_403414 30773 essential YNL118C 2131 - ATCATTCGCCAGACTGGCAA D|717|H D|717|N silent|GCG>GCC|A|715 silent|GCG>GCA|A|715 DCP2 mRNA DeCaPping 970.0 0 1 0 0 0.012778194142295592 P53550 0.278624027967453 0.7203291058540344 51.870742784144795 50.0 0.0 no 11996 chrXIV_403501r 30775 essential YNL118C 2041 + AATCTATAAACGAAACTGTC S|682|C S|682|F DCP2 mRNA DeCaPping 970.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.16607765853435807 P53550 0.0 0.0 33.17297540255771 30.0 0.0 no 11997 chrXIV_403748 30778 essential YNL118C 1797 - TTCTGTTTACTCTGAGTCGA Q|605|H silent|CAG>CAA|Q|605 DCP2 mRNA DeCaPping 970.0 0 1 0 0 0.8925776532381813 P53550 0.09622188657522203 47.25369749831475 40.0 0.0 no 11998 chrXIV_403868 30779 essential YNL118C 1677 - CTTCGGCTGTCTTTTTCGCT R|565|P R|565|Q S|564|T S|564|N DCP2 mRNA DeCaPping 970.0 0 0 0 0 -0.302862352813276 P53550 0.04915456846356392 0.3600490093231201 55.73578842046413 50.0 0.0 no 11999 chrXIV_403903r 30781 essential YNL118C 1639 + ATTCATTGAATGTAGATATT S|548|* S|548|L DCP2 mRNA DeCaPping 970.0 0 0 0 0 -0.4457226250799447 P53550 0.2281374186277389 34.49337072267849 20.0 0.0 no 12000 chrXIV_403987 30782 essential YNL118C 1558 - TGCATCTTGTATACCAGATA A|526|P A|526|T D|525|H D|525|N DCP2 mRNA DeCaPping 970.0 0 0 0 0 0.206272352183212 P53550 0.12197524309158325 0.14945654571056366 0.19242505729198456 0.745259702205658 44.98297447183671 35.0 0.0 no 12001 chrXIV_403997 30783 essential YNL118C 1548 - ATACCAGATACGGAGTCATT G|522|A G|522|D G|522|R G|522|S DCP2 mRNA DeCaPping 970.0 0 0 0 0 -0.3206780625227456 P53550 0.5008363127708435 0.6410854458808899 0.2768525183200836 0.984044909477234 45.40020128105375 40.0 0.0 no 12002 chrXIV_404000r 30784 essential YNL118C 1542 + TTACCAAATGACTCCGTATC P|516|A P|516|S P|516|R P|516|L DCP2 mRNA DeCaPping 970.0 0 0 0 0 -0.05031781978518432 P53550 0.25177720189094543 0.3670481145381928 0.10115579515695572 0.0742327943444252 44.01008817644782 40.0 0.0 no 12003 chrXIV_404156r 30785 essential YNL118C 1386 + AAGCTTAAAATCTTACAGAG L|464|V L|464|F DCP2 mRNA DeCaPping 970.0 0 0 0 0 0.7675834027589173 P53550 0.6838481426239014 0.195860892534256 34.409051081394864 30.0 0.0 no 12004 chrXIV_404261 30787 essential YNL118C 1284 - TAACCAGAGTCCCTCGGTAA G|434|A G|434|D G|434|R G|434|S DCP2 mRNA DeCaPping 970.0 0 1 0 0 -0.8720952194836477 P53550 0.978299915790558 0.2692493498325348 0.13783012330532074 0.8688462972640991 51.809676891241 50.0 0.0 no 12005 chrXIV_404271r 30789 essential YNL118C 1271 + GCCTCCTGCTCCTTTACCGA P|425|R P|425|L P|425|A P|425|S DCP2 mRNA DeCaPping 970.0 0 0 0 0 -0.003350579327106196 P53550 0.5248379707336426 0.4766644835472107 0.8584061264991759 1.0 63.27087058842358 60.0 0.0 no 12006 chrXIV_404321 30790 essential YNL118C 1224 - CCAGAAAGGTTATGCATGTT G|415|R G|415|R DCP2 mRNA DeCaPping 970.0 0 0 0 0 -0.4053352826146972 P53550 0.6736159920692444 0.6736159920692444 45.020147614133 40.0 0.0 no 12007 chrXIV_404321r 30791 essential YNL118C 1221 + CCAAACATGCATAACCTTTC P|408|R P|408|L N|409|K silent|AAC>AAT|N|409 DCP2 mRNA DeCaPping 970.0 0 0 0 0 0.3092428055421853 P53550 0.015011224895715712 0.014340925961732863 0.6159253716468811 43.67547819710535 40.0 0.0 no 12008 chrXIV_404348r 30794 essential YNL118C 1194 + CCTCCGAATCCGATGGCTTT P|400|A P|400|S P|399|R P|399|L DCP2 mRNA DeCaPping 970.0 0 0 0 0 -1.710184378105967 P53550 0.8133739829063416 0.8269648551940918 0.4924136400222778 0.41434189677238464 55.107774197013036 55.00000000000001 0.0 no 12009 chrXIV_404391r 30797 essential YNL118C 1151 + CGCTAACCCTATTCCAACTC A|385|G A|385|V N|386|K silent|AAC>AAT|N|386 DCP2 mRNA DeCaPping 970.0 0 0 0 0 -0.21086546373887427 P53550 0.4353725016117096 0.7500190138816833 0.719712495803833 50.811240087081096 50.0 0.0 no 12010 chrXIV_404498 30798 essential YNL118C 1047 - GACATGAATACGTTAGCCAT M|355|I M|355|I DCP2 mRNA DeCaPping 970.0 0 0 0 0 1.6380022979458295 P53550 44.11557404796707 40.0 0.0 no 12011 chrXIV_404507 30799 essential YNL118C 1038 - ACGTTAGCCATTGGCATAGT V|353|L V|353|I DCP2 mRNA DeCaPping 970.0 0 0 0 0 -0.976797863576058 P53550 0.8635579943656921 0.5598310828208923 51.7130363963783 45.0 0.0 no 12012 chrXIV_404537 30800 essential YNL118C 1008 - ACATTCTTATTGTTAGCAAA V|343|L V|343|I K|341|N silent|AAG>AAA|K|341 DCP2 mRNA DeCaPping 970.0 0 0 0 0 0.4226528120130214 P53550 0.4012568295001984 0.2489496171474457 0.4835273027420044 38.18652145605512 25.0 0.0 no 12013 chrXIV_404639r 30802 essential YNL118C 903 + CAGCATTTGAAAGAGCAATC H|303|D H|303|Y DCP2 mRNA DeCaPping 970.0 0 0 0 0 1.1105584633061445 P53550 0.6677778959274292 0.3196600675582886 40.143775970340926 40.0 0.0 no 12014 chrXIV_404797 30807 essential YNL118C 748 - TTTCAATTGTTCTTCCGCAT L|255|F silent|TTG>TTA|L|255 DCP2 mRNA DeCaPping 970.0 0 0 0 0 0.5423271457623792 P53550 0.0 47.63137860200311 35.0 0.0 no 12015 chrXIV_405014r 30808 essential YNL118C 528 + TACAAAATATTTTTGATATC Y|177|* silent|TAC>TAT|Y|177 DCP2 mRNA DeCaPping 970.0 0 0 0 0 0.5797092145002827 P53550 28.808152987529468 15.0 0.0 no 12016 chrXIV_405149 30809 essential YNL118C 396 - TCTTTAGATATCTTCCCCCT D|139|H D|139|N DCP2 mRNA DeCaPping 970.0 0 1 0 0 -0.3466315893513404 P53550 0.0 0.0 -0.3302200138568878 -0.2552399933338165 1.079800009727478 -0.10499999672174454 54.07261109196917 40.0 0.0 no 12017 chrXIV_405201 30810 essential YNL118C 344 - GTACCAATAAAATTTTACTC V|121|L V|121|I L|120|F silent|TTG>TTA|L|120 DCP2 mRNA DeCaPping 970.0 0 1 0 0 -0.7650220244322934 P53550 0.0 0.0 0.0 0.9983400106430054 -0.2657400071620941 3.696360111236572 34.312793064788536 25.0 0.0 no 12018 chrXIV_405321r 30812 essential YNL118C 221 + GATCATAAAACTATGTCCTC I|75|M silent|ATC>ATT|I|75 DCP2 mRNA DeCaPping 970.0 0 0 0 0 -0.28919656589101994 P53550 0.042689714580774314 39.56395131663936 35.0 0.0 no 12019 chrXIV_405452 30815 essential YNL118C 93 - ACACTCGATAAATCTTCATT S|37|T S|37|N V|38|L V|38|I DCP2 mRNA DeCaPping 970.0 0 0 0 0 0.1882698252004276 P53550 0.3198583126068115 0.028459280729293827 0.061731897294521325 0.31921136379241943 38.92272401055942 30.0 0.0 no 12020 chrXIV_405504r 30816 essential YNL118C 38 + TTCTGTTGATAGAATTTTAG S|14|C S|14|F DCP2 mRNA DeCaPping 970.0 0 0 0 0 0.9242108511990308 P53550 0.0 0.0 35.375133825909636 25.0 0.0 no 12021 chrXIV_412849 30818 essential YNL113W 78 + GAACAGGATGTTGATATGAC Q|28|E Q|28|* RPC19 RNA Polymerase C 142.0 0 0 0 0 0.3545619542272849 P28000 39.43277812771606 40.0 1.0 no 12022 chrXIV_412994r 30823 essential YNL113W 226 - TTTCATTATAACGTAACGAA M|81|I M|81|I RPC19 RNA Polymerase C 142.0 0 1 0 0 0.19698284007379754 P28000 0.0043802410364151 0.0043802410364151 0.6238800287246704 0.6238800287246704 34.350114588743175 25.0 1.0 no 12023 chrXIV_413017 30824 essential YNL113W 246 + AATCCAGACGTAGAATTTTG P|84|A P|84|S P|84|R P|84|L RPC19 RNA Polymerase C 142.0 0 1 0 0 -0.3502429554998469 P28000 0.015664683654904366 0.02309397980570793 0.0028245258145034318 0.001976381754502654 1.2429800033569336 1.3040800094604492 -0.00018000000272877514 1.0856399536132812 39.55693396586304 35.0 1.0 no 12024 chrXIV_413020r 30825 essential YNL113W 252 - TAACCACAAAATTCTACGTC G|90|A G|90|D G|90|R G|90|S RPC19 RNA Polymerase C 142.0 0 0 0 0 0.6787752331859006 P28000 0.17144998908042908 0.006273753475397825 0.002590351272374392 0.014580159448087215 0.07079999893903732 -0.4157199859619141 -0.5169199705123901 0.019680000841617584 38.30241305629988 35.0 1.0 no 12025 chrXIV_413732 30829 essential YNL112W 93 + TCTTACAATGACAGACCACA S|32|C S|32|F Y|33|* silent|TAC>TAT|Y|33 DBP2 Dead Box Protein 546.0 0 0 0 0 -0.5519413171438574 P24783 0.05071093514561653 0.045778095722198486 43.60559285098407 40.0 1.0 no 12026 chrXIV_413704r 30832 essential YNL112W 68 - TATCAGAGTTTCTTCCACCG D|29|H D|29|N DBP2 Dead Box Protein 546.0 0 0 0 0 0.2321831043921896 P24783 0.13003413379192352 0.5514174699783325 50.14777026985126 45.0 1.0 no 12027 chrXIV_413764r 30833 essential YNL112W 128 - AACGACCACCGAAACCACCA R|49|P R|49|H G|48|A G|48|D DBP2 Dead Box Protein 546.0 0 0 0 0 0.6353953584128339 P24783 0.2563197612762451 0.11368679255247115 0.47580885887146 0.3356955349445343 49.82700925705615 55.00000000000001 1.0 no 12028 chrXIV_413999r 30836 essential YNL112W 363 - ACTTCATTCAAAACGTAGTC V|128|L V|128|M E|127|Q E|127|K DBP2 Dead Box Protein 546.0 0 1 0 0 0.8445593158524841 P24783 0.43796756863594055 0.05518820509314537 0.4274536371231079 0.6674613952636719 -2.384959936141968 -2.4784998893737797 39.33507609171852 35.0 1.0 no 12029 chrXIV_414043 30839 essential YNL112W 404 + ACCAACTGGCATTCAATGTC P|136|R P|136|L P|136|A P|136|S DBP2 Dead Box Protein 546.0 0 0 0 0 -2.7546824104858367 P24783 0.0 0.0 0.0 0.0 47.40192478859228 45.0 1.0 yes 12030 chrXIV_414044 30840 essential YNL112W 405 + CCAACTGGCATTCAATGTCA P|136|R P|136|L T|137|S T|137|I DBP2 Dead Box Protein 546.0 0 0 0 0 -0.3494219406447364 P24783 0.0 0.0 0.07246687263250351 0.0009178043110296131 48.20101811907678 45.0 1.0 no 12031 chrXIV_414044r 30841 essential YNL112W 408 - CCCTGACATTGAATGCCAGT Q|142|H silent|CAG>CAA|Q|142 G|143|R G|143|S DBP2 Dead Box Protein 546.0 0 0 0 0 -0.5306177168482249 P24783 0.000742970616556704 0.0009775166399776936 0.13137447834014893 52.558273091416766 50.0 1.0 no 12032 chrXIV_414076 30844 essential YNL112W 437 + GGCTTTATCTGGTAGGGACA A|147|G A|147|V DBP2 Dead Box Protein 546.0 0 0 0 0 0.4491561351803134 P24783 0.03361072763800621 0.017857901751995087 1.2034200429916382 0.049400001764297485 52.55509991748284 50.0 1.0 no 12033 chrXIV_414128 30845 essential YNL112W 489 + ACTTTGTCTTATTGTTTACC T|164|S T|164|I DBP2 Dead Box Protein 546.0 0 0 0 0 1.3092553400799285 P24783 0.0 0.0 44.04326421976066 30.0 1.0 no 12034 chrXIV_414160 30847 essential YNL112W 521 + TATCAACGCTCAACCATTAT I|175|M silent|ATC>ATT|I|175 N|176|K silent|AAC>AAT|N|176 DBP2 Dead Box Protein 546.0 0 0 0 0 0.4714390027281993 P24783 0.0014445515116676688 0.1522541642189026 42.80941251553588 35.0 1.0 no 12035 chrXIV_414173 30849 essential YNL112W 534 + CCATTATTGGCTCCAGGCGA P|179|R P|179|L DBP2 Dead Box Protein 546.0 0 0 0 0 -0.7867136399684374 P24783 0.006160645745694636 0.001825385494157672 56.405421184062455 55.00000000000001 1.0 no 12036 chrXIV_414258r 30851 essential YNL112W 622 - TCTGGAACTATGACCAAACT R|214|T R|214|K DBP2 Dead Box Protein 546.0 0 0 0 0 0.39932398139648895 P24783 0.3131662309169769 0.5579906702041626 1.0465799570083618 0.060619998723268516 42.04088600223349 40.0 1.0 no 12037 chrXIV_414311r 30854 essential YNL112W 675 - TCTCTGATTTGTTGACTTTT R|231|T R|231|K D|232|H D|232|N DBP2 Dead Box Protein 546.0 0 1 0 0 0.8651467696654642 P24783 0.0431675985455513 0.09227956086397172 0.002029342809692025 0.003861932083964348 43.506469554341386 30.0 1.0 no 12038 chrXIV_414427r 30856 essential YNL112W 791 - TATCAGCTTCATCAAGAACC D|270|H D|270|N A|269|P A|269|T DBP2 Dead Box Protein 546.0 0 0 0 0 -5.37319561062616 P24783 0.0014416228514164686 0.003695817897096276 0.0031021093018352985 0.002143226331099868 5.076519966125488 0.1964000016450882 43.867532725731174 40.0 1.0 yes 12039 chrXIV_414443 30857 essential YNL112W 804 + GCTGATAGAATGTTAGATAT A|269|G A|269|V DBP2 Dead Box Protein 546.0 0 0 0 0 -0.15570855067464562 P24783 0.0066693760454654685 0.002050012117251754 1.3594000339508057 -0.9986799955368042 37.877825199062436 30.0 1.0 no 12040 chrXIV_414473r 30858 essential YNL112W 837 - TCAACAATCTTTCTGATTTG D|286|H D|286|N V|285|L V|285|I DBP2 Dead Box Protein 546.0 0 1 0 0 0.9246396630645364 P24783 0.04848894476890564 0.22495052218437195 0.20499300956726074 0.6545072793960571 38.09764322971704 30.0 1.0 no 12041 chrXIV_414506r 30859 essential YNL112W 870 - CACATCAAGGTTTGTCTATC M|296|I M|296|I L|295|F silent|TTG>TTA|L|295 DBP2 Dead Box Protein 546.0 0 0 0 0 -3.3778408475735597 P24783 0.005147126503288746 0.005147126503288746 0.0022128780838102107 44.30387875505961 40.0 1.0 yes 12042 chrXIV_414581 30864 essential YNL112W 942 + GATCCAATTCAAGTTCAAGT P|316|A P|316|S P|316|R P|316|L DBP2 Dead Box Protein 546.0 0 0 0 0 -2.5142196552863787 P24783 0.19741015136241916 0.17158780992031095 0.12560606002807614 0.2348484396934509 42.27272979050696 35.0 1.0 yes 12043 chrXIV_414624r 30865 essential YNL112W 988 - GACGATCTGAGTAATATTAT V|336|L V|336|I Q|334|H silent|CAG>CAA|Q|334 DBP2 Dead Box Protein 546.0 0 0 0 0 0.36822435461311454 P24783 0.006738028954714537 0.3562638461589813 0.0 37.09865036278615 30.0 1.0 no 12044 chrXIV_414768r 30866 essential YNL112W 1132 - TCCATCTTCTCTTAGATACT G|384|R G|384|R G|384|A G|384|E DBP2 Dead Box Protein 546.0 0 0 0 0 -0.5884295990971287 P24783 0.029514716938138005 0.029514716938138005 0.0029512005858123307 0.032192129641771317 46.8892503714361 35.0 1.0 no 12045 chrXIV_414791 30868 essential YNL112W 1152 + TGGCCCGCCTTGGCTATTCA P|386|A P|386|S P|386|R P|386|L DBP2 Dead Box Protein 546.0 0 0 0 0 -0.9503945783942672 P24783 0.3007057905197144 0.23371154069900515 0.2806810736656189 0.11396852135658266 62.74209479567406 60.0 1.0 no 12046 chrXIV_414794r 30869 essential YNL112W 1158 - TCACCATGAATAGCCAAGGC G|392|A G|392|D D|393|H D|393|N DBP2 Dead Box Protein 546.0 0 0 0 0 -0.6678984515151158 P24783 0.0 0.0 0.002114096190780401 0.09996778517961502 49.457994320544564 50.0 1.0 no 12047 chrXIV_414823r 30872 essential YNL112W 1187 - GAACCCAGTCACGTTCTCTT V|402|L V|402|I W|401|C W|401|* DBP2 Dead Box Protein 546.0 0 0 0 0 -0.8326782091082525 P24783 0.012098015286028385 0.10789790749549866 0.0691191703081131 -0.17440000176429749 53.60310816928495 50.0 1.0 no 12048 chrXIV_414859 30873 essential YNL112W 1220 + AAACGGTAGATCCCCAATTA N|408|K silent|AAC>AAT|N|408 DBP2 Dead Box Protein 546.0 0 0 0 0 -0.2743069856444272 P24783 0.3173010945320129 -0.1477999985218048 45.40355437720496 40.0 1.0 no 12049 chrXIV_418075 30874 essential YNL110C 394 - TTCTAAGAAGCCATAATGTC E|138|Q E|138|K NOP15 NucleOlar Protein 220.0 0 0 0 0 0.04047900087007075 P53927 0.0 0.0 40.30608325928921 35.0 0.0 no 12050 chrXIV_418085r 30875 essential YNL110C 381 + ACTGGAAATTCCAGACATTA T|128|S T|128|I NOP15 NucleOlar Protein 220.0 0 0 0 0 0.9658397531675152 P53927 0.0 0.0 41.3315564247231 35.0 0.0 no 12051 chrXIV_418304r 30878 essential YNL110C 162 + GCTTCTGATGATGAGCAGAG A|55|G A|55|V S|56|C S|56|F NOP15 NucleOlar Protein 220.0 0 1 0 0 0.20650016014810224 P53927 0.6119291186332703 0.1629081964492798 0.05874489992856979 0.19767430424690247 47.89080753191217 50.0 0.0 no 12052 chrXIV_418400 30880 essential YNL110C 69 - AACTCTTCTTTCTCCTGTAT E|29|D silent|GAG>GAA|E|29 E|29|Q E|29|K NOP15 NucleOlar Protein 220.0 0 0 0 0 0.15000237815688966 P53927 0.3682050406932831 0.3578588962554932 0.7039022445678711 48.00393021225705 35.0 0.0 no 12053 chrXIV_427751r 30881 essential YNL103W 19 - GCTGTATGAGTCGCCTTCGT S|13|T S|13|N MET4 METhionine requiring 672.0 0 0 0 0 -0.7977141892199934 P32389 0.9512869715690612 0.9536849856376648 0.7101083397865295 0.17734967172145846 57.29043954317518 55.00000000000001 1.0 no 12054 chrXIV_427774 30883 essential YNL103W 39 + ACGGAATTCATAAATCTCTT T|14|R T|14|M MET4 METhionine requiring 672.0 0 0 0 0 0.08259543800654852 P32389 0.9476869702339172 0.9502379894256592 0.03532915562391281 0.015963423997163773 38.18904215954848 30.0 1.0 no 12055 chrXIV_428168r 30889 essential YNL103W 436 - GGCAAACGCACTCAACTCAA A|152|P A|152|T silent|GCG>GCC|A|150 silent|GCG>GCA|A|150 MET4 METhionine requiring 672.0 0 0 0 0 0.5483269230628158 P32389 0.9573720097541808 0.9523990154266356 0.0 0.0 46.10201459402873 50.0 1.0 no 12056 chrXIV_428208r 30890 essential YNL103W 476 - TGCTCGGCTTATCCTCGTCT S|165|T S|165|N silent|CCG>CCC|P|164 silent|CCG>CCA|P|164 MET4 METhionine requiring 672.0 0 0 0 0 -0.2047313757751144 P32389 0.9512869715690612 0.9536849856376648 0.7089325785636902 0.8033236861228943 58.913313543390245 55.00000000000001 1.0 no 12057 chrXIV_428196 30891 essential YNL103W 461 + TTCTTTCATCTTCCCAGACG S|155|C S|155|F F|156|L silent|TTC>TTT|F|156 MET4 METhionine requiring 672.0 0 0 0 0 1.216315988846976 P32389 0.945252001285553 0.9294660091400146 0.9387490153312684 0.013486242853105068 0.007203144021332264 0.0 51.144591794139565 45.0 1.0 no 12058 chrXIV_428323r 30896 essential YNL103W 591 - CTTCTTTGAGTCAAGAAGTG R|203|T R|203|K MET4 METhionine requiring 672.0 0 1 0 0 0.8636364745912991 P32389 0.932735025882721 0.955805003643036 0.0 0.0 41.36309416400025 40.0 1.0 no 12059 chrXIV_428363r 30897 essential YNL103W 631 - AGACTTTGATTGGTCGTATT K|216|N silent|AAG>AAA|K|216 MET4 METhionine requiring 672.0 0 0 0 0 -1.3445283859606194 P32389 0.9355990290641784 0.020663963630795482 44.08414759581847 35.0 1.0 no 12060 chrXIV_428419 30898 essential YNL103W 684 + AACGGCGAAACAAACAACTT N|229|K silent|AAC>AAT|N|229 silent|GGC>GGG|G|230 silent|GGC>GGT|G|230 MET4 METhionine requiring 672.0 0 0 0 0 0.0937504918163377 P32389 0.9439849853515624 0.6440804600715637 37.8486388515675 40.0 1.0 no 12061 chrXIV_428373r 30899 essential YNL103W 641 - ACGAAAATCGAGACTTTGAT silent|TCG>TCC|S|220 silent|TCG>TCA|S|220 MET4 METhionine requiring 672.0 0 0 0 0 0.5724326694081057 P32389 37.168256472709864 35.0 1.0 no 12062 chrXIV_428503r 30901 essential YNL103W 771 - GTCATATTAGTTGCGTCAGC M|263|I M|263|I MET4 METhionine requiring 672.0 0 0 0 0 1.284772978307397 P32389 0.9553959965705872 0.9553959965705872 0.22232575714588165 0.22232575714588165 49.8907128487291 45.0 1.0 no 12063 chrXIV_428504r 30902 essential YNL103W 772 - TGTCATATTAGTTGCGTCAG M|263|I M|263|I MET4 METhionine requiring 672.0 0 0 0 0 0.697516301856652 P32389 0.9553959965705872 0.9553959965705872 0.22232575714588165 0.22232575714588165 45.87946637696564 40.0 1.0 no 12064 chrXIV_428535r 30903 essential YNL103W 803 - CAACATTTGTGAAGCCGCCA V|274|L V|274|I MET4 METhionine requiring 672.0 0 0 0 0 0.5588534156108753 P32389 0.9539830088615416 0.9574310183525084 0.12935741245746613 0.1776265949010849 50.48691304511817 50.0 1.0 no 12065 chrXIV_428575 30906 essential YNL103W 840 + AACAATACTACCGGTGACAA N|281|K silent|AAC>AAT|N|281 MET4 METhionine requiring 672.0 0 0 0 0 0.4931184700982417 P32389 0.9439849853515624 0.20550866425037384 41.37344890378574 40.0 1.0 no 12066 chrXIV_428585r 30907 essential YNL103W 853 - CGCATCCACTCCATTGTCAC A|291|P A|291|T D|290|H D|290|N MET4 METhionine requiring 672.0 0 0 0 0 0.6272366763143307 P32389 0.9573720097541808 0.9523990154266356 0.9486550092697144 0.956179976463318 0.3437439203262329 0.9544552564620972 0.08303965628147125 0.6922290325164795 55.28882478058904 55.00000000000001 1.0 no 12067 chrXIV_428657r 30909 essential YNL103W 925 - AGCAGAAGTGACATTGCTTA A|315|P A|315|T MET4 METhionine requiring 672.0 0 1 0 0 0.4642955772528353 P32389 0.9573720097541808 0.9523990154266356 0.09054438024759293 0.5206051468849182 44.99199150184654 40.0 1.0 no 12068 chrXIV_428691 30911 essential YNL103W 956 + TTCACAACAACGAAAACATT S|320|* S|320|L Q|321|E Q|321|* MET4 METhionine requiring 672.0 0 1 0 0 0.27463801424811146 P32389 0.9298099875450134 0.9590039849281312 0.4864055812358856 0.40080910921096796 34.319816904865945 30.0 1.0 no 12069 chrXIV_428759r 30912 essential YNL103W 1027 - GTCAGGAACAGTTATATTGG D|349|H D|349|N MET4 METhionine requiring 672.0 0 0 0 0 -0.16817081868508016 P32389 0.9486550092697144 0.956179976463318 0.017402997240424156 0.2372024804353714 42.236332982900926 40.0 1.0 no 12070 chrXIV_429024 30918 essential YNL103W 1289 + TGTCTTAATACCACCCTCTC silent|GTC>GTG|V|431 silent|GTC>GTT|V|431 MET4 METhionine requiring 672.0 0 0 0 0 0.7685564007381694 P32389 51.55567800600704 45.0 1.0 no 12071 chrXIV_428967 30919 essential YNL103W 1232 + CAACACCAATGACAGTCAAG N|412|K silent|AAC>AAT|N|412 T|413|S T|413|I MET4 METhionine requiring 672.0 0 1 0 0 0.5865904805957272 P32389 0.9439849853515624 0.9491789937019348 0.9472420215606691 1.0 0.6916639804840088 0.1736207902431488 41.47254447342822 45.0 1.0 no 12072 chrXIV_429079 30924 essential YNL103W 1344 + TCGCCTTCGTTCAATGAGCA P|450|A P|450|S S|449|W S|449|L MET4 METhionine requiring 672.0 0 0 0 0 0.5392485542956796 P32389 0.9562489986419678 0.9498909711837769 0.9288619756698608 0.9298099875450134 0.7364447712898254 0.7099565267562866 0.0590311735868454 0.4726726710796356 52.71964973978687 50.0 1.0 no 12073 chrXIV_429117 30925 essential YNL103W 1382 + TTCTTTTCTAAGCTCCATTT S|462|C S|462|F MET4 METhionine requiring 672.0 0 0 0 0 0.4621710847685363 P32389 0.945252001285553 0.9294660091400146 0.11495480686426165 0.13759039342403412 46.06179837066646 30.0 1.0 no 12074 chrXIV_429082r 30926 essential YNL103W 1350 - ACACCGTGCTCATTGAACGA G|456|A G|456|D V|457|L V|457|I MET4 METhionine requiring 672.0 0 0 0 0 0.16348672716607465 P32389 0.9499930143356324 0.9446240067481996 0.9539830088615416 0.9574310183525084 1.0 0.6073570251464844 0.30557048320770264 0.18734078109264374 49.19557138084088 50.0 1.0 no 12075 chrXIV_430147 30927 essential YNL102W 60 + ACATCCATCGATGATTACGA T|21|R T|21|I S|22|C S|22|F 1 Series([], Name: modification, dtype: object) 0 0 0 -0.1434050417770622 P13382 1.0001499652862549 0.977836012840271 0.8083360195159912 0.8030449748039246 0.5515559911727905 0.2136237770318985 0.027121011167764664 0.026826608926057816 44.350943222410876 40.0 1.0 no 12076 chrXIV_430151r 30929 essential YNL102W 67 - GTCACCTTCGTAATCATCGA D|29|H D|29|N G|28|A G|28|D 0 1 0 0 0.5962059797215059 P13382 0.780888020992279 0.8920490145683289 0.9692220091819764 0.9980559945106506 0.07996323704719542 0.3370059132575989 0.7785075902938843 0.6271129846572876 48.70167005107919 45.0 1.0 no 12077 chrXIV_430236r 30933 essential YNL102W 152 - AATCGTCATGCAGCAATTCC D|57|H D|57|N D|56|H D|56|N 0 0 0 0 0.008638304904994731 P13382 0.7648259997367859 0.7861419916152954 0.7651649713516235 0.792149007320404 0.0 0.0 0.0 0.0 48.16674406704982 45.0 1.0 no 12078 chrXIV_430407r 30936 essential YNL102W 323 - GCAGCATATCTGTAATCTGG silent|CTG>CTC|L|114 silent|CTG>CTA|L|114 M|113|I M|113|I 0 0 0 0 0.34376184748510563 P13382 1.0086100101470947 1.0086100101470947 0.3954746425151825 0.3954746425151825 47.199467314034855 45.0 1.0 no 12079 chrXIV_430410r 30937 essential YNL102W 326 - TTCGCAGCATATCTGTAATC R|115|P R|115|Q silent|CTG>CTC|L|114 silent|CTG>CTA|L|114 0 1 0 0 0.3177737293118564 P13382 0.8372070193290709 0.8856920003890991 0.2123274058103561 0.4452671706676483 45.37595179235746 40.0 1.0 no 12080 chrXIV_430597r 30938 essential YNL102W 513 - GACGATTTAAATTCACTAGT silent|TCG>TCC|S|177 silent|TCG>TCA|S|177 0 0 0 0 1.1853118350904932 P13382 37.35559756928478 30.0 1.0 no 12081 chrXIV_430758 30940 essential YNL102W 671 + GCGCTACGCAAATGATGTAC silent|CGC>CGG|R|225 silent|CGC>CGT|R|225 R|225|G R|225|C 0 0 0 0 0.2056757589337844 P13382 0.9010109901428224 0.7793110013008118 0.3597034811973572 0.05120175331830978 0.5030400156974792 0.6281999945640564 46.0919249475146 50.0 1.0 no 12082 chrXIV_430806r 30941 essential YNL102W 722 - GTCTCTTTGTGGCTACTACT R|247|T R|247|K K|246|N silent|AAG>AAA|K|246 0 1 0 0 -0.4388797759246156 P13382 0.9566799998283386 1.0069799423217771 0.8800010085105896 0.5191447138786316 0.831951379776001 0.495415598154068 52.50456216340535 45.0 1.0 no 12083 chrXIV_430805r 30942 essential YNL102W 721 - TCTCTTTGTGGCTACTACTG K|246|N silent|AAG>AAA|K|246 R|247|T R|247|K 0 1 0 0 0.24360422880650826 P13382 0.8800010085105896 0.9566799998283386 1.0069799423217771 0.495415598154068 0.5191447138786316 0.831951379776001 49.53730139019149 45.0 1.0 no 12084 chrXIV_430807r 30943 essential YNL102W 723 - TGTCTCTTTGTGGCTACTAC R|247|T R|247|K K|246|N silent|AAG>AAA|K|246 0 1 0 0 0.3758812629403098 P13382 0.9566799998283386 1.0069799423217771 0.8800010085105896 0.5191447138786316 0.831951379776001 0.495415598154068 50.440252899097906 45.0 1.0 no 12085 chrXIV_430999 30946 essential YNL102W 912 + TCACCGTTTGTCACAGCACC P|306|A P|306|S S|305|* S|305|L 0 1 0 0 -0.6833383764327702 P13382 0.8941649794578552 0.9055590033531188 0.8381469845771791 0.34932178258895874 0.6466027498245239 0.09277845919132233 55.985792570774386 55.00000000000001 1.0 no 12086 chrXIV_431173 30949 essential YNL102W 1086 + AACAACACTTTGATTTTATT N|363|K silent|AAC>AAT|N|363 N|364|K silent|AAC>AAT|N|364 0 0 0 0 0.3837674807997271 P13382 0.96491801738739 0.9408429861068726 0.1991403251886368 0.232390359044075 34.59762192816464 20.0 1.0 no 12087 chrXIV_431227 30950 essential YNL102W 1140 + TCAGCCATGGTTCAAATCAA S|381|* S|381|L A|382|G A|382|V 0 0 0 0 -0.44808109092511134 P13382 0.7592020034790039 0.9722920060157776 0.9365249872207642 0.0 0.2341562956571579 0.035465192049741745 45.557825220622426 40.0 1.0 no 12088 chrXIV_431262 30951 essential YNL102W 1175 + GCTATTTTTCCTTCCAAGAG L|393|V silent|CTA>TTA|L|393 0 0 0 0 0.19416924890713755 P13382 0.9393200278282166 0.03057537041604519 48.104004967034136 40.0 1.0 no 12089 chrXIV_431320r 30953 essential YNL102W 1236 - CCATATTTATCCATCAGTAA G|419|R G|419|R 0 0 0 0 0.3497629929901558 P13382 0.9227700233459472 0.9227700233459472 0.11533036082983016 0.11533036082983016 42.7491560453156 30.0 1.0 no 12090 chrXIV_431404r 30955 essential YNL102W 1320 - TTCAAATAATCACTTTCAGA L|446|F silent|TTG>TTA|L|446 0 0 0 0 0.19443095542893152 P13382 0.864503026008606 0.1218983232975006 35.51530775737632 25.0 1.0 no 12091 chrXIV_431495 30958 essential YNL102W 1408 + CCTTTTATCATGTTTTTGGT silent|ACC>ACG|T|470 silent|ACC>ACT|T|470 0 0 0 0 -0.052298693969993856 P13382 45.951763209442674 30.0 1.0 no 12092 chrXIV_431565 30960 essential YNL102W 1478 + ACCATGCTGGTTAGATATAA P|494|R P|494|L P|494|A P|494|S 0 0 0 0 -0.7304340049351802 P13382 0.772055983543396 0.7770130038261414 0.822363018989563 0.7841659784317017 0.0 0.0 0.0 0.0 43.55923663713077 35.0 1.0 no 12093 chrXIV_431566r 30961 essential YNL102W 1482 - CCCTTTATATCTAACCAGCA K|500|N silent|AAG>AAA|K|500 G|501|R G|501|R 0 0 0 0 1.0123489736750804 P13382 0.8955669999122621 0.866470992565155 0.866470992565155 0.2540593147277832 0.2270171046257019 0.2270171046257019 49.2999911330387 40.0 1.0 no 12094 chrXIV_431607 30962 essential YNL102W 1520 + TCGTAATGCTTCTCACTGTG R|508|G R|508|C 0 0 0 0 0.4230894613778221 P13382 0.8902300000190735 0.7334439754486084 0.3342868387699127 0.04747811704874039 47.57498149685802 45.0 1.0 no 12095 chrXIV_431732r 30964 essential YNL102W 1648 - AATCTCTTGCTTATTTTCCT E|555|D silent|GAG>GAA|E|555 E|555|Q E|555|K 0 0 0 0 0.22403048530592745 P13382 0.8525829911231995 0.8526179790496826 0.8217790126800537 0.0 0.0 0.0 46.231558193282815 30.0 1.0 no 12096 chrXIV_431715 30965 essential YNL102W 1628 + TCAGACGTTAATGAATCCCA Q|544|E Q|544|* T|545|R T|545|M 0 0 0 0 -0.902522135498922 P13382 0.8646489977836609 0.8059260249137878 0.8661289811134338 0.04584771022200584 0.005496973637491465 0.0030647439416497946 44.82132236246536 40.0 1.0 no 12097 chrXIV_431772 30966 essential YNL102W 1685 + AGCATATAGAAATATCTCGT A|563|G A|563|V 0 0 0 0 -0.362851748231586 P13382 0.9687110185623168 1.0146700143814087 0.04284708946943283 1.0 38.4399864104343 30.0 1.0 no 12098 chrXIV_431821r 30967 essential YNL102W 1737 - ACTAAAGTACACAAGTCGTC V|586|L V|586|I 0 0 0 0 1.0995701199210353 P13382 0.9148759841918944 0.9650099873542786 0.3419126570224762 0.5842239260673523 40.262492625701725 40.0 1.0 no 12099 chrXIV_431868 30969 essential YNL102W 1781 + CCCATTAGGTTTAGCTGCAC P|595|R P|595|L P|595|A P|595|S 0 0 0 0 0.15666715204423892 P13382 0.7879430055618286 0.7912690043449402 0.8289999961853027 0.8213149905204773 0.0 0.0 0.0 0.0 54.021065012683884 50.0 1.0 no 12100 chrXIV_432078r 30975 essential YNL102W 1994 - GCCAAGTCCTTCTTAAACGA W|671|S W|671|* W|671|C W|671|* 0 0 0 0 -0.07014445328615881 P13382 0.8525530099868774 0.7252539992332458 0.004108232911676168 0.0029090226162225012 48.11171815022419 45.0 1.0 no 12101 chrXIV_432100r 30976 essential YNL102W 2016 - TTTCCTCTACCGAATTTTTC G|678|A G|678|E G|678|R G|678|R 0 0 0 0 0.3249111297471491 P13382 0.9596980214118958 0.8826779723167419 0.8884990215301514 0.8884990215301514 0.975753664970398 0.9808523654937744 0.695092499256134 0.695092499256134 45.85252773314437 35.0 1.0 no 12102 chrXIV_432206 30978 essential YNL102W 2119 + TAACACCCAAATGTCAAAGT T|708|R T|708|I P|709|A P|709|S 0 0 0 0 0.6129063262495407 P13382 0.8652939796447754 0.9225230216979979 0.9438430070877076 0.940729022026062 0.04493845254182816 0.1229955479502678 0.2369064688682556 0.12748241424560547 40.1642669233276 35.0 1.0 no 12103 chrXIV_432207 30979 essential YNL102W 2120 + AACACCCAAATGTCAAAGTT T|708|R T|708|I P|709|A P|709|S 0 0 0 0 -0.197097958998328 P13382 0.8652939796447754 0.9225230216979979 0.9438430070877076 0.940729022026062 0.04493845254182816 0.1229955479502678 0.2369064688682556 0.12748241424560547 40.885288665905534 35.0 1.0 no 12104 chrXIV_432306r 30980 essential YNL102W 2222 - TCATACTATTTACATCATTT M|747|I M|747|I S|746|T S|746|N 0 0 0 0 0.9505224746400824 P13382 0.9723860025405884 0.9723860025405884 0.9542059898376464 0.9486160278320312 0.0388118177652359 0.0388118177652359 0.6019045114517212 0.5025997757911682 36.974929601985366 20.0 1.0 no 12105 chrXIV_432443r 30983 essential YNL102W 2359 - TCTTGTACCGCCTAGCGTTT R|793|T R|793|K 0 0 0 0 -0.5711536419906326 P13382 0.8077030181884766 0.8510779738426208 0.0 0.0 56.31786896847257 50.0 1.0 no 12106 chrXIV_432523r 30986 essential YNL102W 2439 - CTTCTATTGCCTTCTTTGTC R|819|T R|819|K 0 0 0 0 0.2500502476985934 P13382 0.8866249918937683 0.9768329858779908 0.08163262903690338 1.0 50.72991543777505 40.0 1.0 no 12107 chrXIV_432597 30987 essential YNL102W 2510 + TTCTAAAAAGGCAAAATATC S|838|C S|838|F 0 1 0 0 -0.7257505649102225 P13382 0.7908710241317749 0.7873690128326416 0.00886121578514576 0.008955998346209526 30.63167907395473 25.0 1.0 no 12108 chrXIV_432598 30988 essential YNL102W 2511 + TCTAAAAAGGCAAAATATCA S|838|C S|838|F 0 1 0 0 0.13444868364556134 P13382 0.7908710241317749 0.7873690128326416 0.00886121578514576 0.008955998346209526 31.715022276177532 25.0 1.0 no 12109 chrXIV_432637r 30989 essential YNL102W 2553 - TTCTTATGAAGACCTTTCTC K|857|N silent|AAG>AAA|K|857 0 0 0 0 0.2360437021572725 P13382 0.9335089921951294 0.2796904444694519 43.315635449114495 35.0 1.0 no 12110 chrXIV_432775r 30995 essential YNL102W 2691 - CCCTGATCCACCTCTGAAGG Q|903|H silent|CAG>CAA|Q|903 G|904|R G|904|S 0 0 0 0 -3.2562732958302663 P13382 0.8052330017089844 0.7677010297775269 0.8507559895515442 0.07363341748714447 0.0 0.0 56.45815540151546 60.0 1.0 yes 12111 chrXIV_432804 30996 essential YNL102W 2717 + ACCAAGGTTATTAGCTAATC P|907|R P|907|L P|907|A P|907|S 0 0 0 0 -0.22359686027129327 P13382 0.7830290198326111 0.7724429965019226 0.8079249858856201 0.7830780148506165 0.0 0.0 0.0 0.0 42.12679140926872 35.0 1.0 no 12112 chrXIV_432876r 31000 essential YNL102W 2792 - TATCACATTGAACTCGCTTA D|937|H D|937|N C|936|S C|936|Y 0 0 0 0 0.030082290690566643 P13382 0.8618299961090088 0.9269660115242004 0.8670669794082642 0.9548799991607666 0.0 0.0 0.054898392409086234 0.4075141251087189 42.38487862532668 35.0 1.0 no 12113 chrXIV_432985 31001 essential YNL102W 2898 + GCCATGTTAGTCACTAATAA silent|GCC>GCG|A|967 silent|GCC>GCT|A|967 A|967|G A|967|V 0 0 0 0 -0.587964239077075 P13382 0.7803109884262085 0.7805960178375244 0.0 0.0 43.24795932676818 35.0 1.0 no 12114 chrXIV_433233 31002 essential YNL102W 3146 + CGCTGCTTTGACTGTAAATT A|1050|G A|1050|V A|1051|G A|1051|V 0 0 0 0 -0.09786557257122776 P13382 0.8444499969482422 0.8385509848594666 0.8669720292091371 0.8017169833183289 0.0 0.0 0.0 0.0 44.56043564657796 40.0 1.0 no 12115 chrXIV_433356 31003 essential YNL102W 3269 + AAACACCATCCTGTCAGATA N|1091|K silent|AAC>AAT|N|1091 T|1092|S T|1092|I 0 0 0 0 0.03244415324794153 P13382 0.9712759852409364 0.9568750262260436 0.9860659837722778 0.04170582443475723 0.6198805570602417 0.16869959235191345 45.674053397915536 40.0 1.0 no 12116 chrXIV_433380r 31005 essential YNL102W 3296 - CTTCTTGCAATGCTTCTTCT E|1105|Q E|1105|K 0 0 0 0 -0.5473680144091158 P13382 0.9881889820098876 0.9795669913291932 0.40483325719833374 0.9111346602439879 49.66190286830891 40.0 1.0 no 12117 chrXIV_433381r 31006 essential YNL102W 3297 - ACTTCTTGCAATGCTTCTTC V|1106|L V|1106|M E|1105|Q E|1105|K 0 0 0 0 0.1315784068071877 P13382 0.9567949771881104 0.880407989025116 0.9881889820098876 0.9795669913291932 0.0582260861992836 0.01077398844063282 0.40483325719833374 0.9111346602439879 48.2307842641099 40.0 1.0 no 12118 chrXIV_457776r 31007 essential YNL088W 75 - ACAGAACCGATATAAGTGTC V|32|L V|32|I G|30|A G|30|D TOP2 TOPoisomerase 1428.0 0 0 0 0 0.2210214098122351 P06786 0.04670821130275726 0.5380413532257079 0.0 0.0 -1.104099988937378 -0.2567600011825561 3.155280113220215 3.9274001121521 41.051768542610944 40.0 1.0 no 12119 chrXIV_457938r 31009 essential YNL088W 237 - ACATCGATTCGTTTCATCGA V|86|L V|86|I D|85|H D|85|N TOP2 TOPoisomerase 1428.0 0 0 0 0 -0.11727717486306205 P06786 0.01923118345439434 0.27177363634109497 0.011111974716186523 0.02406684868037701 2.422640085220337 -0.435699999332428 0.04577999934554099 0.4339799880981445 45.59483702462892 40.0 1.0 no 12120 chrXIV_458086r 31011 essential YNL088W 385 - CTTCTCATCATCATCATAAT E|134|D silent|GAG>GAA|E|134 E|134|Q E|134|K TOP2 TOPoisomerase 1428.0 0 1 0 0 0.194456870090641 P06786 0.09476254880428314 0.40679413080215454 0.013609105721116066 0.41596001386642456 -0.6507599949836731 -0.3428800106048584 41.06859561717158 30.0 1.0 no 12121 chrXIV_458200 31013 essential YNL088W 496 + GCCAGAAATATGTTCAAAAA Q|167|E Q|167|* silent|GGC>GGG|G|166 silent|GGC>GGT|G|166 TOP2 TOPoisomerase 1428.0 0 0 0 0 -0.3018246051137692 P06786 0.046688206493854516 0.4368399977684021 35.789151848202664 30.0 1.0 no 12122 chrXIV_458285 31015 essential YNL088W 581 + TACAAAGGTGACATTTAAGC T|195|R T|195|I TOP2 TOPoisomerase 1428.0 0 0 0 0 -0.8923273061588117 P06786 0.0022735162638127804 0.008445351384580134 -1.158660054206848 -1.6875200271606443 37.717217496749576 35.0 1.0 no 12123 chrXIV_458301 31016 essential YNL088W 597 + AAGCCGGATTTAACCAGATT P|201|A P|201|S P|201|R P|201|L TOP2 TOPoisomerase 1428.0 0 0 0 0 0.05940290723042629 P06786 0.0 0.0 0.0 0.0 3.4559400081634517 5.360620021820068 8.766940116882324 1.809440016746521 45.57600588675347 40.0 1.0 no 12124 chrXIV_458304r 31017 essential YNL088W 603 - ATTCCGAATCTGGTTAAATC G|207|A G|207|E G|207|R G|207|R TOP2 TOPoisomerase 1428.0 0 0 0 0 0.320684860191411 P06786 0.04241708293557167 0.061736986041069024 0.03826267272233963 0.03826267272233963 2.56060004234314 2.6792800426483154 2.2251999378204346 2.2251999378204346 40.792086134033866 35.0 1.0 no 12125 chrXIV_458314r 31018 essential YNL088W 613 - TAGCTCTTTCATTCCGAATC E|210|D silent|GAG>GAA|E|210 E|210|Q E|210|K TOP2 TOPoisomerase 1428.0 0 0 0 0 0.25882712824295795 P06786 0.5951927900314331 0.4936760663986206 0.8676835894584656 0.1254200041294098 0.1333400011062622 -0.18964000046253204 46.839061697203256 40.0 1.0 no 12126 chrXIV_458397 31019 essential YNL088W 693 + GACATTAATGTCTATCTGAA D|232|E silent|GAC>GAT|D|232 TOP2 TOPoisomerase 1428.0 0 0 0 0 0.5498083258021278 P06786 0.18617425858974454 0.324400007724762 37.612743236700055 30.0 1.0 no 12127 chrXIV_458532r 31022 essential YNL088W 831 - ATTCTCTCATAAAGAATAGT R|283|T R|283|K E|282|D silent|GAG>GAA|E|282 TOP2 TOPoisomerase 1428.0 0 0 0 0 0.5901650570540239 P06786 0.5718165636062622 0.9374036192893982 0.2254033088684082 0.3624800145626068 0.1540600061416626 0.5477799773216248 35.41512900667635 25.0 1.0 no 12128 chrXIV_458647r 31027 essential YNL088W 946 - GTCTGTTATGTAATTGACAT D|322|H D|322|N TOP2 TOPoisomerase 1428.0 0 0 0 0 0.21198847004328286 P06786 0.00852346234023571 0.22318732738494876 -0.014320000074803831 0.3337799906730652 40.22435518494768 30.0 1.0 no 12129 chrXIV_458815 31029 essential YNL088W 1111 + CAACAAGAGTCAAAGATTTT T|372|R T|372|I TOP2 TOPoisomerase 1428.0 0 0 0 0 0.5024940172405103 P06786 0.3727620244026184 0.4092893898487091 0.033720001578330994 1.0609400272369385 34.88553038222392 30.0 1.0 no 12130 chrXIV_458840r 31031 essential YNL088W 1139 - ATTCAAGAGGAATCTCACAA E|386|Q E|386|K TOP2 TOPoisomerase 1428.0 0 0 0 0 -0.2858864396649145 P06786 0.07708059996366501 0.32771241664886475 1.4164199829101562 1.6986199617385864 39.118431539848594 35.0 1.0 no 12131 chrXIV_458998r 31032 essential YNL088W 1297 - TTCTTTTGTACCGGCTTTGT E|439|Q E|439|K TOP2 TOPoisomerase 1428.0 0 0 0 0 0.4447996207076155 P06786 0.3163575232028961 0.6070343852043152 1.2389980554580688 0.6492980122566223 51.67479590640472 40.0 1.0 no 12132 chrXIV_459031 31034 essential YNL088W 1327 + GTACTTTAGTTCTGACAGAA T|444|S T|444|I TOP2 TOPoisomerase 1428.0 0 0 0 0 1.3412626842577822 P06786 0.019660415127873417 0.012207304127514362 1.842527985572815 -3.0433459281921387 41.611321841604926 35.0 1.0 no 12133 chrXIV_459032 31035 essential YNL088W 1328 + TACTTTAGTTCTGACAGAAG T|444|S T|444|I TOP2 TOPoisomerase 1428.0 0 0 0 0 0.29112456159632266 P06786 0.019660415127873417 0.012207304127514362 1.842527985572815 -3.0433459281921387 39.07632090914189 35.0 1.0 no 12134 chrXIV_459120r 31038 essential YNL088W 1419 - TTCAGCATTTTACCACGAAG silent|CTG>CTC|L|479 silent|CTG>CTA|L|479 M|478|I M|478|I TOP2 TOPoisomerase 1428.0 0 0 0 0 -0.1427782023451517 P06786 0.04895331710577011 0.04895331710577011 -0.10640399903059006 -0.10640399903059006 44.089894089428746 40.0 1.0 no 12135 chrXIV_459238 31039 essential YNL088W 1534 + ATACAAAATCTTTAAGATAT T|513|R T|513|I TOP2 TOPoisomerase 1428.0 0 0 0 0 -1.1822471875198248 P06786 0.1249857172369957 0.4116220772266388 -0.8254140019416809 -1.0566220283508299 28.938390163381648 15.0 1.0 no 12136 chrXIV_459342 31040 essential YNL088W 1638 + CCTGGTCTTTTGGATATCCA P|547|R P|547|L L|549|V L|549|F TOP2 TOPoisomerase 1428.0 0 0 0 0 0.22332931721119267 P06786 0.0 0.0 0.0 0.0 3.5056920051574707 11.746150016784668 52.74608040883675 45.0 1.0 no 12137 chrXIV_459447r 31042 essential YNL088W 1746 - TCTCTCCATTTTTCATAGTC R|588|T R|588|K E|589|Q E|589|K TOP2 TOPoisomerase 1428.0 0 0 0 0 0.4083184400887615 P06786 0.10293418169021606 1.0 0.02159780636429787 0.01662684790790081 1.6068220138549805 -0.8609560132026672 -0.56740802526474 0.20516200363636014 47.6470602767011 35.0 1.0 no 12138 chrXIV_459584r 31044 essential YNL088W 1883 - TATCATTACCCTGCAAAGAA D|634|H D|634|N TOP2 TOPoisomerase 1428.0 0 0 0 0 -1.9944466025749807 P06786 0.008611277677118778 0.035381123423576355 42.464959542719896 35.0 1.0 no 12139 chrXIV_459751 31047 essential YNL088W 2047 + TTTCTTTGGCCGATAATATA S|684|C S|684|F TOP2 TOPoisomerase 1428.0 0 0 0 0 0.11032658049235056 P06786 0.0 0.0 0.3024120032787323 -2.0665900707244877 42.30998479888029 30.0 1.0 no 12140 chrXIV_459774 31048 essential YNL088W 2070 + TCGATTCCCAATGTTTTAGA S|691|W S|691|L P|693|A P|693|S TOP2 TOPoisomerase 1428.0 0 0 0 0 1.1102336504887955 P06786 0.0 0.0 0.07790259271860123 0.015906378626823425 0.8731279969215393 -0.6581799983978271 2.527385950088501 4.033760070800781 45.357247622879754 35.0 1.0 no 12141 chrXIV_459878 31049 essential YNL088W 2174 + ACCATACGTGAGCGAATGTA P|726|R P|726|L P|726|A P|726|S TOP2 TOPoisomerase 1428.0 0 0 0 0 -3.7424511852437967 P06786 0.005316940136253835 0.005523151252418757 0.04054706916213036 0.02213165909051895 1.4651520252227783 1.9878779649734497 1.917523980140686 2.0394399166107178 46.14744853602986 45.0 1.0 yes 12142 chrXIV_459921 31053 essential YNL088W 2217 + TCATTGGCACAAACTATTAT S|740|* S|740|L TOP2 TOPoisomerase 1428.0 0 0 0 0 -0.14109274266820848 P06786 0.0 -0.44494199752807617 39.453869662611226 30.0 1.0 no 12143 chrXIV_459943 31055 essential YNL088W 2239 + GGCTAGCCCAAAACTTTGTT L|748|V silent|CTA>TTA|L|748 A|749|G A|749|V TOP2 TOPoisomerase 1428.0 0 0 0 0 -0.9158848790792466 P06786 0.011700994335114956 0.0 0.0 3.0395319461822514 0.891480028629303 2.3920719623565674 49.97008250570963 45.0 1.0 no 12144 chrXIV_460167 31060 essential YNL088W 2463 + CTTCCTATGATTCTTGTTAA P|823|A P|823|S P|823|R P|823|L TOP2 TOPoisomerase 1428.0 0 0 0 0 -0.1149082531641393 P06786 0.0 0.0 0.0 0.0 2.447518110275269 4.772304058074951 16.28849220275879 2.6730420589447017 42.57283607358903 30.0 1.0 no 12145 chrXIV_460176 31062 essential YNL088W 2472 + ATTCTTGTTAACGGTGCTGA L|826|V L|826|F TOP2 TOPoisomerase 1428.0 0 0 0 0 0.2488995095992865 P06786 0.0 0.0 1.4877899885177612 10.243887901306152 46.53053061143999 40.0 1.0 no 12146 chrXIV_460285 31063 essential YNL088W 2581 + AGCTTGAGCAAATGCATCCG L|862|V L|862|F TOP2 TOPoisomerase 1428.0 0 0 0 0 -0.5641255075409777 P06786 0.5159932971000671 0.6605161428451538 2.39711594581604 2.682497978210449 48.928024416671754 50.0 1.0 no 12147 chrXIV_460291 31064 essential YNL088W 2587 + AGCAAATGCATCCGTGGTTT Q|864|E Q|864|* TOP2 TOPoisomerase 1428.0 0 0 0 0 0.2761029616603882 P06786 1.0 0.3278380036354065 49.964816871223604 45.0 1.0 no 12148 chrXIV_460292 31065 essential YNL088W 2588 + GCAAATGCATCCGTGGTTTA Q|864|E Q|864|* TOP2 TOPoisomerase 1428.0 0 0 0 0 -0.4007747196578476 P06786 1.0 0.3278380036354065 49.34294324389453 45.0 1.0 no 12149 chrXIV_460302r 31067 essential YNL088W 2601 - CCGGTCCATCCCCTAAACCA G|874|R G|874|S W|872|C W|872|* TOP2 TOPoisomerase 1428.0 0 0 0 0 -1.163470749670334 P06786 0.0 0.0 0.0024538005236536264 30.32179832458496 11.395649909973145 3.9593079090118413 59.49550826233883 60.0 1.0 no 12150 chrXIV_460421 31072 essential YNL088W 2717 + AACTTGGACATCGACTATAA T|907|S T|907|I TOP2 TOPoisomerase 1428.0 0 0 0 0 0.956579929315472 P06786 0.27185001969337463 0.3699711263179779 0.8197020292282104 -1.222082018852234 39.049602663104615 35.0 1.0 no 12151 chrXIV_460446 31073 essential YNL088W 2742 + TACTTACTTTTAGGTTTAAG Y|915|* silent|TAC>TAT|Y|915 L|917|V L|917|F TOP2 TOPoisomerase 1428.0 0 0 0 0 0.25410077607542103 P06786 0.05940258502960205 0.03322458639740944 1.1452499628067017 0.17819799482822418 36.277894118728796 25.0 1.0 no 12152 chrXIV_460607 31077 essential YNL088W 2903 + GCCTATAAGTTTGATGAATA P|969|R P|969|L P|969|A P|969|S TOP2 TOPoisomerase 1428.0 0 0 0 0 -0.15254039271090342 P06786 0.2842473089694977 0.16580894589424133 0.4758298993110657 0.6292982697486877 0.5061179995536804 -0.10141000151634216 0.4854300022125244 0.579584002494812 39.467071701995735 30.0 1.0 no 12153 chrXIV_460608r 31078 essential YNL088W 2907 - ACCATATTCATCAAACTTAT M|975|I M|975|I V|976|L V|976|I TOP2 TOPoisomerase 1428.0 0 0 0 0 0.6500168923968654 P06786 0.06984233856201172 0.06984233856201172 0.04894227534532547 0.2577554285526276 1.7939740419387815 1.7939740419387815 1.4069520235061646 0.9640960097312928 38.31030652982139 25.0 1.0 no 12154 chrXIV_460641r 31079 essential YNL088W 2940 - TACTTCTTGATTTTCCCGTG K|986|N silent|AAG>AAA|K|986 K|985|N silent|AAG>AAA|K|985 TOP2 TOPoisomerase 1428.0 0 0 0 0 0.8518820862661964 P06786 0.00455815764144063 0.06630489230155945 0.9264580011367798 0.8028140068054199 48.64569570626179 40.0 1.0 no 12155 chrXIV_460669r 31080 essential YNL088W 2968 - TTCGCTTAATATTTCATTCA E|996|Q E|996|K S|995|T S|995|N TOP2 TOPoisomerase 1428.0 0 0 0 0 0.35992254361458953 P06786 0.04636085405945778 0.03567542135715485 0.34763094782829285 0.2263025194406509 -0.6723260283470154 -0.4937320053577423 -0.35056400299072266 -0.17070800065994265 40.180466385086156 25.0 1.0 no 12156 chrXIV_460816 31083 essential YNL088W 3112 + TAACAGTCACCAATAAGCCT T|1039|R T|1039|I TOP2 TOPoisomerase 1428.0 0 0 0 0 0.9537591112070176 P06786 0.11046727746725082 0.3634684085845947 -0.2542400062084198 -0.22172999382019046 45.13879242074546 40.0 1.0 no 12157 chrXIV_460778r 31084 essential YNL088W 3077 - TCATTTTAATAAATTTTACT M|1032|I M|1032|I TOP2 TOPoisomerase 1428.0 0 0 0 0 0.6852942248545737 P06786 0.12612149119377136 0.12612149119377136 2.416330099105835 2.416330099105835 29.734669940119147 10.0 1.0 no 12158 chrXIV_460849 31086 essential YNL088W 3145 + TCCAAGAACTTGAGAATTTA Q|1050|E Q|1050|* I|1049|M silent|ATC>ATT|I|1049 TOP2 TOPoisomerase 1428.0 0 0 0 0 -0.6243996575402591 P06786 0.832118034362793 0.010965539142489432 -0.16289199888706207 0.09953399747610092 37.423681628083436 30.0 1.0 no 12159 chrXIV_460875r 31087 essential YNL088W 3174 - TTACCTTCCTTATTAAATCT G|1064|A G|1064|D G|1064|R G|1064|S TOP2 TOPoisomerase 1428.0 0 0 0 0 0.6068901702154845 P06786 0.9301857352256776 0.527073860168457 0.4857197403907776 0.7136422991752625 3.3816258907318115 4.116973876953125 4.280724048614502 4.038060188293457 41.20409829338337 25.0 1.0 no 12160 chrXIV_477188r 31090 high_effect YNL080C 822 + AGTCTCTCCGATAACAGTGA L|276|V L|276|F silent|CTC>CTG|L|276 silent|CTC>CTT|L|276 0 0 0 0 0.31767581980262044 P53938 0.9779649972915648 0.9867290258407592 0.6049665808677673 0.7175047993659973 48.239616117340404 45.0 0.0 no 12161 chrXIV_477223 31092 high_effect YNL080C 790 - AACATCTACTGTACTTTCGT V|270|L V|270|I D|269|H D|269|N 0 0 0 0 -0.1510504361524758 P53938 0.9769399762153624 0.9846090078353882 0.9728149771690368 0.9840490221977234 0.4413833618164063 0.28514981269836426 0.1199629157781601 0.5109222531318665 43.44704522607884 35.0 0.0 no 12162 chrXIV_477324 31093 high_effect YNL080C 689 - CCTCTTGTACTTCGCCTTCC E|236|Q E|236|K E|236|D silent|GAG>GAA|E|236 0 0 0 0 0.6996270605830232 P53938 0.9857460260391236 0.9736970067024232 0.9778879880905152 59.18878476078879 55.00000000000001 0.0 no 12163 chrXIV_477349r 31096 high_effect YNL080C 661 + CCTCGGATCTGAGGTATATC S|222|W S|222|L silent|ACC>ACG|T|221 silent|ACC>ACT|T|221 0 0 0 0 0.8818384807890891 P53938 0.966612994670868 0.9753659963607788 0.0 0.0 49.69431026504674 50.0 0.0 no 12164 chrXIV_477528r 31102 high_effect YNL080C 482 + GATCGTCAAGTACTCTACTG I|162|M silent|ATC>ATT|I|162 silent|GTC>GTG|V|163 silent|GTC>GTT|V|163 0 0 0 0 0.2508200163784973 P53938 0.9225469827651978 0.0 44.76016198376732 45.0 0.0 no 12165 chrXIV_477600 31105 high_effect YNL080C 413 - CCAGGCACCAAAGTGAGCAA silent|CTG>CTC|L|144 silent|CTG>CTA|L|144 C|143|S C|143|Y 0 0 0 0 -0.2845723298735949 P53938 0.966803014278412 0.949554979801178 0.13319078087806702 0.003596755675971508 51.16167570939081 55.00000000000001 0.0 no 12166 chrXIV_477764 31110 high_effect YNL080C 249 - AACGCATCTCTTAGTGATTG silent|GCG>GCC|A|89 silent|GCG>GCA|A|89 A|89|P A|89|T 0 0 0 1 0.539868346276831 P53938 0.9770879745483398 0.9687960147857666 0.17993910610675812 1.0 43.694377258866545 40.0 0.0 no 12167 chrXIV_477828r 31113 high_effect YNL080C 182 + CATCTTCACATCTCTGCGGA I|62|M silent|ATC>ATT|I|62 F|63|L silent|TTC>TTT|F|63 0 0 0 0 0.8163630509710023 P53938 0.9787610173225404 0.9584370255470276 0.19785577058792114 0.3505588471889496 51.88708512829817 50.0 0.0 no 12168 chrXIV_477981 31114 high_effect YNL080C 32 - TGGCATACTTGTCCTCATGA A|17|P A|17|T 0 0 0 0 -0.118396429052208 P53938 0.9846779704093932 0.97638601064682 0.28311002254486084 0.5901899933815002 51.440417301424134 45.0 0.0 no 12169 chrXIV_485733r 31117 essential YNL075W 129 - TCATCTTCTGCTAGTTCCTT E|50|Q E|50|K D|49|H D|49|N IMP4 Interacting with Mpp10p 290.0 0 1 0 0 0.2301596019919752 P53941 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.4661124348640442 0.8070628643035889 0.2336520254611969 0.4110077619552612 52.8908452743031 40.0 1.0 no 12170 chrXIV_485979r 31120 essential YNL075W 375 - TTACAAGCATCCACTAGATT C|131|S C|131|Y IMP4 Interacting with Mpp10p 290.0 0 0 0 0 -0.8611034281444669 P53941 0.9421560168266296 0.9290120005607604 0.023065909743309018 0.0016589228762313724 43.58212650398031 35.0 1.0 no 12171 chrXIV_486063 31121 essential YNL075W 456 + ACCATATCACATTTTCCACA silent|ACC>ACG|T|153 silent|ACC>ACT|T|153 T|153|S T|153|I IMP4 Interacting with Mpp10p 290.0 0 0 0 0 0.7889397116891501 P53941 0.9491789937019348 0.9472420215606691 0.006886339280754328 1.0 46.95498120840131 35.0 1.0 no 12172 chrXIV_486123 31123 essential YNL075W 516 + AGACATGATATTATAAATGC H|174|D H|174|Y IMP4 Interacting with Mpp10p 290.0 0 0 0 0 0.4802211570686617 P53941 0.9473130106925964 0.9489949941635132 0.018522225320339203 0.004434359725564718 33.116183575483774 25.0 1.0 no 12173 chrXIV_486193r 31124 essential YNL075W 589 - GACTACTCTTTTCCCTAAAG V|203|L V|203|I V|202|L V|202|I IMP4 Interacting with Mpp10p 290.0 0 0 0 0 0.41628923900842507 P53941 0.9539830088615416 0.9574310183525084 0.9539830088615416 0.9574310183525084 0.29979264736175537 0.1857990175485611 0.061347618699073785 0.3063550293445587 44.949739788533755 40.0 1.0 no 12174 chrXIV_506181r 31126 high_effect YNL064C 894 + CCAGGTGAAGTTATTGCCCC P|299|R P|299|L YDJ1 Yeast dnaJ 409.0 0 0 0 0 -0.4661218501907118 P25491 0.0039322832599282265 0.004390664864331485 0.4534900188446045 1.4690299034118652 1.384269952774048 0.9934099912643432 56.42506597602585 55.00000000000001 0.0 no 12175 chrXIV_506313 31129 high_effect YNL064C 765 - TCTCTCTTGAAGCTCTTGTG R|261|T R|261|K D|262|H D|262|N YDJ1 Yeast dnaJ 409.0 0 0 0 0 -0.4515966826994513 P25491 0.0 0.0 0.031356193125247955 0.12032519280910492 1.7237699031829834 1.4019399881362915 0.22359000146389008 -0.08557000011205672 49.09297249795753 45.0 0.0 no 12176 chrXIV_506358 31131 high_effect YNL064C 720 - ACATCACCTGGAATGACATC V|247|L V|247|I D|246|H D|246|N YDJ1 Yeast dnaJ 409.0 0 0 0 0 -0.018494689086837632 P25491 0.09792213886976242 0.9174622297286988 0.0 0.0 -0.8299999833106995 0.527999997138977 2.501800060272217 0.4697999954223633 45.38551476420866 45.0 0.0 no 12177 chrXIV_506360 31133 high_effect YNL064C 718 - ATCACCTGGAATGACATCTG D|246|H D|246|N G|245|A G|245|D YDJ1 Yeast dnaJ 409.0 0 0 0 0 -1.2118936502932718 P25491 0.0 0.0 0.0 0.0 2.501800060272217 0.4697999954223633 5.078000068664551 10.918600082397461 45.43800176588826 45.0 0.0 no 12178 chrXIV_506529r 31136 high_effect YNL064C 546 + ACAGAGTGTGATGTCTGTCA T|183|R T|183|I YDJ1 Yeast dnaJ 409.0 1 Series([], Name: modification, dtype: object) 0 0 0 -1.0757801463972978 P25491 0.013058479875326157 0.016942137852311134 -0.7728000283241272 0.5866000056266785 49.20637591109585 45.0 0.0 no 12179 chrXIV_506533 31137 high_effect YNL064C 545 - GACAGACATCACACTCTGTT C|188|S C|188|Y V|187|L V|187|I YDJ1 Yeast dnaJ 409.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.7646174080934396 P25491 0.0 0.0 0.05472208932042122 0.033439960330724716 5.184999942779541 31.459400177001953 -0.24660000205039975 -0.119999997317791 47.251289169987785 45.0 0.0 no 12180 chrXIV_506542 31138 high_effect YNL064C 536 - CACACTCTGTTTGGAATCTT C|185|S C|185|Y E|184|D silent|GAG>GAA|E|184 YDJ1 Yeast dnaJ 409.0 1 Series([], Name: modification, dtype: object) 0 0 0 -1.1040235933010634 P25491 0.0 0.0 0.015352378599345684 5.065000057220459 43.26459884643555 0.16259999573230746 45.57048617267316 40.0 0.0 no 12181 chrXIV_506669 31140 high_effect YNL064C 409 - ACATAGGATCTGTTTGTTAA C|143|S C|143|Y YDJ1 Yeast dnaJ 409.0 1 Series([], Name: modification, dtype: object) 0 0 0 -1.6551613455546554 P25491 0.0 0.0 -0.7516000270843506 39.75859832763672 40.463753408188154 30.0 0.0 no 12182 chrXIV_506746 31141 high_effect YNL064C 332 - GCTTGATATCTTTACCTCTT K|117|N silent|AAG>AAA|K|117 YDJ1 Yeast dnaJ 409.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.7739280949046934 P25491 0.07241190969944 1.3766000270843506 47.69919894609171 35.0 0.0 no 12183 chrXIV_506826 31145 high_effect YNL064C 252 - CCAAAACCGAATCCACCACC G|91|R G|91|S G|89|A G|89|D YDJ1 Yeast dnaJ 409.0 0 0 0 0 0.5832997801521944 P25491 0.3171168267726898 0.6596620678901672 1.0 0.7259357571601868 49.86281904426221 55.00000000000001 0.0 no 12184 chrXIV_506898 31149 high_effect YNL064C 180 - TCATATATATCTCTCTTTTC D|67|H D|67|N YDJ1 Yeast dnaJ 409.0 0 1 0 0 0.5214584088666605 P25491 0.0 0.0 39.52410194041306 25.0 0.0 no 12185 chrXIV_506977 31151 high_effect YNL064C 101 - CACTTGGATTCTTATCTGGA S|40|T S|40|N YDJ1 Yeast dnaJ 409.0 0 1 0 0 -0.06915637423026122 P25491 0.2286238521337509 1.0 45.882906957091215 40.0 0.0 no 12186 chrXIV_507026 31152 high_effect YNL064C 52 - TTTCTTAATTTCGACATCAG K|23|N silent|AAG>AAA|K|23 YDJ1 Yeast dnaJ 409.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.7241841257336641 P25491 0.0 38.807929924075104 30.0 0.0 no 12187 chrXIV_507036 31153 high_effect YNL064C 42 - TCGACATCAGTGGCAGTTAC E|21|Q E|21|K V|20|L V|20|I YDJ1 Yeast dnaJ 409.0 0 1 0 0 -1.5529581571335294 P25491 0.06881856173276901 0.007568797562271357 0.21018590033054352 0.13028956949710846 -0.7227540016174316 -0.538070023059845 49.61347022987508 50.0 0.0 no 12188 chrXIV_509123r 31155 essential YNL062C 1067 + CCTATATGACGGTCTTGTAA L|357|V silent|CTA>TTA|L|357 GCD10 General Control Derepressed 478.0 0 0 0 0 0.6953695105956358 P41814 0.28246694803237915 45.072613841734274 40.0 0.0 no 12189 chrXIV_509216 31158 essential YNL062C 977 - TCTTACCACCTTTTAATGCA K|332|N silent|AAG>AAA|K|332 G|331|A G|331|D GCD10 General Control Derepressed 478.0 0 0 0 0 0.4565795370109524 P41814 0.22917918860912326 0.7870398163795471 0.6251281499862671 47.046070807834845 35.0 0.0 no 12190 chrXIV_509361 31159 essential YNL062C 832 - AAACTTCAGCAAATCCAAGT K|283|N silent|AAG>AAA|K|283 silent|CTG>CTC|L|282 silent|CTG>CTA|L|282 GCD10 General Control Derepressed 478.0 0 0 0 0 -0.5976261565759533 P41814 0.2316875904798508 40.49033725383032 35.0 0.0 no 12191 chrXIV_509416r 31160 essential YNL062C 774 + GACAATGAAAGCAAATCCAA D|259|E silent|GAC>GAT|D|259 GCD10 General Control Derepressed 478.0 0 0 0 0 1.0776491018241234 P41814 36.65879831680286 35.0 0.0 no 12192 chrXIV_509573r 31164 essential YNL062C 617 + CGACAAAGGCGATATCCAAA D|207|E silent|GAC>GAT|D|207 GCD10 General Control Derepressed 478.0 0 0 0 0 0.963553997949721 P41814 1.0 41.945659493172066 45.0 0.0 no 12193 chrXIV_509587r 31166 essential YNL062C 603 + TTACAATTCTTAATCGACAA Q|203|E Q|203|* GCD10 General Control Derepressed 478.0 0 0 0 0 0.4799697340464576 P41814 0.9766067266464232 34.87499566682283 25.0 0.0 no 12194 chrXIV_509783 31167 essential YNL062C 410 - TTTCTTCAACGGTTAACTCT E|143|Q E|143|K E|142|Q E|142|K GCD10 General Control Derepressed 478.0 0 0 0 0 -0.6669771029580654 P41814 0.2630071341991425 0.04376253858208656 0.4833341240882874 0.3048659563064575 43.44184511044631 35.0 0.0 no 12195 chrXIV_509628 31168 essential YNL062C 565 - ATACTCAACGGTGAAGTACT E|194|D silent|GAG>GAA|E|194 E|194|Q E|194|K GCD10 General Control Derepressed 478.0 0 0 0 0 0.10826324291974282 P41814 0.4841459691524506 0.3193191885948181 0.34872344136238104 42.343915920112245 40.0 0.0 no 12196 chrXIV_509784 31169 essential YNL062C 409 - TTCTTCAACGGTTAACTCTT E|143|Q E|143|K E|142|Q E|142|K GCD10 General Control Derepressed 478.0 0 0 0 0 -0.2608116431256048 P41814 0.2630071341991425 0.04376253858208656 0.4833341240882874 0.3048659563064575 43.44184511044642 35.0 0.0 no 12197 chrXIV_509815r 31170 essential YNL062C 375 + AATCAGAATCTGGTTAACAT Q|127|E Q|127|* GCD10 General Control Derepressed 478.0 0 0 0 0 -0.21187292664170784 P41814 0.0915653333067894 37.556691213481656 30.0 0.0 no 12198 chrXIV_509971r 31172 essential YNL062C 219 + CCAAAGAACAAAATTCCCAT P|74|R P|74|L GCD10 General Control Derepressed 478.0 0 0 0 0 0.4448489067418288 P41814 39.50186938133749 35.0 0.0 no 12199 chrXIV_510031r 31173 essential YNL062C 159 + ACTTTCGAGATATATTATGA T|54|S T|54|I F|55|L silent|TTC>TTT|F|55 GCD10 General Control Derepressed 478.0 0 0 0 0 0.08007101308998896 P41814 0.17040182650089264 0.008006169460713862 0.03255710005760193 36.552313585272884 25.0 0.0 no 12200 chrXIV_510097r 31176 essential YNL062C 93 + TCTGTATCATTAGGAAAATT S|32|C S|32|F GCD10 General Control Derepressed 478.0 0 0 0 0 0.5881297583501139 P41814 0.1330731213092804 0.12563008069992065 35.46521711938817 25.0 0.0 no 12201 chrXIV_510106r 31179 essential YNL062C 84 + CCCAACACCTCTGTATCATT silent|CCC>CCG|P|29 silent|CCC>CCT|P|29 P|29|R P|29|L GCD10 General Control Derepressed 478.0 0 0 0 0 1.1780518591199889 P41814 0.25160521268844604 0.14588719606399536 51.63831508887415 45.0 0.0 no 12202 chrXIV_510174 31181 essential YNL062C 19 - AACGTGCTGATTAAAATCTA V|13|L V|13|I Q|11|H silent|CAG>CAA|Q|11 GCD10 General Control Derepressed 478.0 0 0 0 0 1.3659685612889625 P41814 0.2701621651649475 0.2491714209318161 0.22004327178001404 36.696430831238615 30.0 0.0 no 12203 chrXIV_510566 31182 essential YNL061W 26 + GCAAGCCGCCCCACCAACCC Q|10|E Q|10|* A|11|G A|11|V NOP2 NucleOlar Protein 618.0 0 0 0 0 -3.594108558968621 P40991 0.0 1.0 0.07428964972496033 66.14492494089905 75.0 1.0 yes 12204 chrXIV_510579r 31185 essential YNL061W 42 - GCCTGAAACTCCTCCAGGGT Q|20|H silent|CAG>CAA|Q|20 A|21|P A|21|T NOP2 NucleOlar Protein 618.0 0 0 0 0 -5.7559996124660575 P40991 0.2861379683017731 0.27062925696372986 0.564199686050415 58.77416316333711 60.0 1.0 yes 12205 chrXIV_510583r 31186 essential YNL061W 46 - TCTTGCCTGAAACTCCTCCA R|22|T R|22|K A|21|P A|21|T NOP2 NucleOlar Protein 618.0 0 0 0 0 -2.993708229235713 P40991 0.5836637616157532 0.9834909439086914 0.27062925696372986 0.564199686050415 54.43657703246686 50.0 1.0 yes 12206 chrXIV_510584r 31187 essential YNL061W 47 - TTCTTGCCTGAAACTCCTCC R|22|T R|22|K A|21|P A|21|T NOP2 NucleOlar Protein 618.0 0 0 0 0 -0.6797343490621649 P40991 0.5836637616157532 0.9834909439086914 0.27062925696372986 0.564199686050415 53.534193906785156 50.0 1.0 no 12207 chrXIV_510648r 31188 essential YNL061W 111 - TCATCCCCTTGCGTGGTAGA E|44|Q E|44|K D|43|H D|43|N NOP2 NucleOlar Protein 618.0 0 0 0 0 -0.6995572392004276 P40991 0.6000810265541077 0.9942546486854552 0.1359037160873413 0.5025481581687927 59.072232496582096 55.00000000000001 1.0 no 12208 chrXIV_510704 31189 essential YNL061W 164 + ATTCAAGAAATCTAGAAAAG F|56|L silent|TTC>TTT|F|56 NOP2 NucleOlar Protein 618.0 0 0 0 0 -1.2448765191936864 P40991 0.4508695900440216 28.951403086407822 25.0 1.0 no 12209 chrXIV_510790r 31190 essential YNL061W 253 - ATCATCAAATAAAGATTTCC D|91|H D|91|N D|90|H D|90|N NOP2 NucleOlar Protein 618.0 0 0 0 0 -0.22969024204682675 P40991 0.22287809848785398 0.5204931497573853 0.06997929513454437 0.3553610146045685 34.42590519374255 25.0 1.0 no 12210 chrXIV_511030r 31195 essential YNL061W 493 - CGCTTCCACTAACTCCATTT A|171|P A|171|T E|170|Q E|170|K NOP2 NucleOlar Protein 618.0 0 0 0 0 -0.08543810279995298 P40991 0.2312292605638504 0.6986823081970215 0.35748279094696045 0.4806554317474365 51.095822139891204 45.0 1.0 no 12211 chrXIV_511070 31196 essential YNL061W 530 + AGCAGACATATTGCCCACTG A|178|G A|178|V D|179|E silent|GAC>GAT|D|179 NOP2 NucleOlar Protein 618.0 0 0 0 0 -0.39026551200988935 P40991 0.40512678027153015 0.332449734210968 0.3274388909339905 51.755428983815825 50.0 1.0 no 12212 chrXIV_511122r 31197 essential YNL061W 585 - GTTCTTGTGGAAGTTAAATT R|201|T R|201|K NOP2 NucleOlar Protein 618.0 0 0 0 0 0.2211031577888492 P40991 0.1415536105632782 0.4076292812824249 39.04513517385249 30.0 1.0 no 12213 chrXIV_510914r 31199 essential YNL061W 377 - CGTCATCTGAAAAAATTGGG D|132|H D|132|N D|131|H D|131|N NOP2 NucleOlar Protein 618.0 0 0 0 0 -0.8995574458919824 P40991 0.01693148910999298 0.042552441358566284 0.12222373485565186 0.29811426997184753 37.58982523233765 40.0 1.0 no 12214 chrXIV_511354r 31200 essential YNL061W 817 - CTTCAAGGTGTTGGTTCTGA L|278|F silent|TTG>TTA|L|278 NOP2 NucleOlar Protein 618.0 0 0 0 0 -0.29158510736950555 P40991 0.0 49.393101694728394 45.0 1.0 no 12215 chrXIV_511363 31201 essential YNL061W 823 + CCAACACCTTGAAGACCAGA silent|ACC>ACG|T|275 silent|ACC>ACT|T|275 N|276|K silent|AAC>AAT|N|276 NOP2 NucleOlar Protein 618.0 0 0 0 0 -1.1788968609588506 P40991 0.0 48.43558278346661 50.0 1.0 no 12216 chrXIV_511363r 31202 essential YNL061W 826 - CCTTCTGGTCTTCAAGGTGT R|282|T R|282|K R|281|T R|281|K NOP2 NucleOlar Protein 618.0 0 0 0 0 1.4032783272889289 P40991 0.004959670826792717 0.030510686337947845 0.05767203494906425 0.4261018335819245 55.04856419720568 50.0 1.0 no 12217 chrXIV_511423 31205 essential YNL061W 883 + ATCTACAACCTATTGGTTCT L|296|V silent|CTA>TTA|L|296 Q|297|E Q|297|* NOP2 NucleOlar Protein 618.0 0 0 0 0 0.02860734586608038 P40991 0.0 1.0 45.52171271423651 35.0 1.0 no 12218 chrXIV_511467 31206 essential YNL061W 927 + TTCGATTCCCAAGTCCCAAT F|310|L silent|TTC>TTT|F|310 NOP2 NucleOlar Protein 618.0 0 0 0 0 0.7603187510178889 P40991 0.0 52.032840028579976 45.0 1.0 no 12219 chrXIV_511764r 31213 essential YNL061W 1227 - TCAAAACCTCCAATTACCTT D|416|H D|416|N G|414|A G|414|D NOP2 NucleOlar Protein 618.0 0 0 0 0 -0.15738922455353282 P40991 0.005155747290700674 0.12651480734348294 0.0 0.0 43.84316072740296 35.0 1.0 no 12220 chrXIV_511805r 31215 essential YNL061W 1268 - TAACACCAGTACCGGAACAT V|429|L V|429|I G|428|A G|428|D NOP2 NucleOlar Protein 618.0 0 0 0 0 -2.596368616610493 P40991 0.0 0.0 0.0 0.0 45.7777700315371 45.0 1.0 yes 12221 chrXIV_513363 31219 high_effect YNL059C 1553 - GATCATTATCTATTGTCGCT D|524|H D|524|N ARP5 Actin-Related Protein 755.0 0 0 0 0 0.3314234519298618 P53946 0.042620759457349784 0.2886060476303101 45.15912458765297 35.0 0.0 no 12222 chrXIV_513634 31220 high_effect YNL059C 1282 - TTCTTCTTTAGCCTTTTGCC E|434|Q E|434|K E|433|Q E|433|K ARP5 Actin-Related Protein 755.0 0 0 0 0 -0.5642942209829536 P53946 0.07584623247385025 0.07472637295722961 0.3978009521961212 0.4765671491622925 53.49677467918628 40.0 0.0 no 12223 chrXIV_513733 31222 high_effect YNL059C 1183 - ATCAAGCAAATCAAATTTCT D|401|H D|401|N L|399|F silent|TTG>TTA|L|399 ARP5 Actin-Related Protein 755.0 0 0 0 0 0.6033168847525494 P53946 0.005614530760794878 0.017298391088843346 0.02118636667728424 35.203647530784906 25.0 0.0 no 12224 chrXIV_513762 31223 high_effect YNL059C 1154 - TGTCTTCATTCATTTCATCC D|391|H D|391|N E|390|Q E|390|K ARP5 Actin-Related Protein 755.0 0 0 0 0 -0.40433769949825343 P53946 0.1018161028623581 0.3620832562446594 0.3073072135448456 0.23047542572021484 47.54088155381811 35.0 0.0 no 12225 chrXIV_513792 31225 high_effect YNL059C 1124 - CATCTTCTGCTTCAACCATT D|381|H D|381|N E|380|Q E|380|K ARP5 Actin-Related Protein 755.0 0 1 0 0 0.2035886170040415 P53946 0.09915460646152496 0.3586179912090301 0.5840569138526917 0.9157918095588684 48.80017394380054 40.0 0.0 no 12226 chrXIV_513793 31226 high_effect YNL059C 1123 - ATCTTCTGCTTCAACCATTT D|381|H D|381|N E|380|Q E|380|K ARP5 Actin-Related Protein 755.0 0 1 0 0 0.5721429624964052 P53946 0.09915460646152496 0.3586179912090301 0.5840569138526917 0.9157918095588684 47.78002693215433 35.0 0.0 no 12227 chrXIV_513878r 31227 high_effect YNL059C 1035 + CTCTCGGTTTTGCAAAACGC silent|CTC>CTG|L|346 silent|CTC>CTT|L|346 S|347|W S|347|L ARP5 Actin-Related Protein 755.0 0 0 0 1 -1.0016519616055135 P53946 0.014858098700642587 0.2428434789180756 47.269175808739526 50.0 0.0 no 12228 chrXIV_513894r 31228 high_effect YNL059C 1019 + ACCTAAGAAGAAAGTACTCT P|341|R P|341|L P|341|A P|341|S ARP5 Actin-Related Protein 755.0 0 0 0 0 0.4532726191752962 P53946 0.5536169409751892 0.3097577393054962 0.7866074442863464 0.9058786630630492 38.57972855879552 35.0 0.0 no 12229 chrXIV_513893 31229 high_effect YNL059C 1023 - ACCGAGAGTACTTTCTTCTT silent|TCG>TCC|S|347 silent|TCG>TCA|S|347 V|348|L V|348|I ARP5 Actin-Related Protein 755.0 0 0 0 0 -0.26424453513490564 P53946 0.6893242597579956 0.8926396369934082 48.3193249013267 40.0 0.0 no 12230 chrXIV_513909 31230 high_effect YNL059C 1007 - TCTTAGGTTCGTCAATTAAT K|342|N silent|AAG>AAA|K|342 ARP5 Actin-Related Protein 755.0 0 0 0 0 0.6231879529854575 P53946 0.0333753265440464 40.60781078931308 30.0 0.0 no 12231 chrXIV_514062 31232 high_effect YNL059C 854 - CTTCTGTCTTTTGAGGTTGA E|291|Q E|291|K ARP5 Actin-Related Protein 755.0 0 0 0 0 0.488365133238139 P53946 0.2681610882282257 0.0648307278752327 48.213142672418826 40.0 0.0 no 12232 chrXIV_514107 31233 high_effect YNL059C 809 - CTACCACATCATTTGTATCA V|276|L V|276|I silent|GTG>GTC|V|275 silent|GTG>GTA|V|275 ARP5 Actin-Related Protein 755.0 0 0 0 0 1.138373009642643 P53946 0.08641553670167923 0.7274488210678101 44.92895244311889 35.0 0.0 no 12233 chrXIV_514122 31234 high_effect YNL059C 794 - TATCAAGGTTCTCCAAGGTG D|271|H D|271|N ARP5 Actin-Related Protein 755.0 0 0 0 0 0.6465041637700031 P53946 0.095610111951828 0.3024443984031677 47.17216510146813 45.0 0.0 no 12234 chrXIV_514211 31235 high_effect YNL059C 705 - TGCAAATAAGACATCTTTGT L|241|F silent|TTG>TTA|L|241 ARP5 Actin-Related Protein 755.0 0 0 0 0 -0.1927380954473409 P53946 0.7066799402236938 38.132019472715115 30.0 0.0 no 12235 chrXIV_514322 31238 high_effect YNL059C 594 - ATACCTGCACCATCAACTAC G|204|A G|204|D G|204|R G|204|S ARP5 Actin-Related Protein 755.0 0 0 0 0 0.5477742474904101 P53946 1.0 0.059647712856531136 0.048372805118560784 0.327400803565979 48.12096439116232 45.0 0.0 no 12236 chrXIV_514495r 31244 high_effect YNL059C 418 + TGGCAACTGTTCAATCACAA A|141|G A|141|V T|142|S T|142|I ARP5 Actin-Related Protein 755.0 0 0 0 0 0.29038269234002023 P53946 0.5383991003036499 0.1033398061990738 0.7296715378761292 0.0961662530899048 43.4539056637484 40.0 0.0 no 12237 chrXIV_514517 31245 high_effect YNL059C 399 - AGTCTTTCGGTAAGTAATAT R|139|T R|139|K ARP5 Actin-Related Protein 755.0 0 0 0 0 -0.8663655525178865 P53946 0.5903944969177246 0.9357128739356996 39.99476472863853 30.0 0.0 no 12238 chrXIV_514563r 31246 high_effect YNL059C 350 + CACTTTTCATCATTTGGGAG T|118|S T|118|I ARP5 Actin-Related Protein 755.0 0 0 0 0 0.4589061863416332 P53946 0.9117617011070251 0.13167886435985565 44.76016198376732 40.0 0.0 no 12239 chrXIV_514568r 31247 high_effect YNL059C 345 + GACTACACTTTTCATCATTT D|116|E silent|GAC>GAT|D|116 Y|117|* silent|TAC>TAT|Y|117 ARP5 Actin-Related Protein 755.0 0 0 0 0 -0.15057660639399054 P53946 0.17775008082389832 41.957554389202706 30.0 0.0 no 12240 chrXIV_514569r 31248 high_effect YNL059C 344 + GGACTACACTTTTCATCATT D|116|E silent|GAC>GAT|D|116 Y|117|* silent|TAC>TAT|Y|117 ARP5 Actin-Related Protein 755.0 0 0 0 0 0.6180482268647387 P53946 0.17775008082389832 44.184121244649475 35.0 0.0 no 12241 chrXIV_514597 31249 high_effect YNL059C 319 - TTCTTCAGTGAGATTCCAAT E|113|Q E|113|K E|112|Q E|112|K ARP5 Actin-Related Protein 755.0 0 0 0 0 1.0065647529587942 P53946 0.5871313810348511 0.9214056134223938 0.0 0.0 44.786199433357865 35.0 0.0 no 12242 chrXIV_514739 31254 high_effect YNL059C 177 - GCATTCGGAAAAATATGTGT A|66|P A|66|T silent|CCG>CCC|P|64 silent|CCG>CCA|P|64 ARP5 Actin-Related Protein 755.0 0 0 0 0 0.7183800677579848 P53946 0.06262317299842833 0.12509682774543762 39.12107675595883 35.0 0.0 no 12243 chrXIV_514886 31261 high_effect YNL059C 30 - TCTATCACTACTGCCTTAAG D|17|H D|17|N silent|GTG>GTC|V|15 silent|GTG>GTA|V|15 ARP5 Actin-Related Protein 755.0 0 1 0 0 0.2419007831769463 P53946 0.13292008638381958 0.5164833068847656 45.31963989335105 40.0 0.0 no 12244 chrXIV_555076 31262 essential YNL039W 28 + CACGCTTTGCCCCTAAAGTA R|11|G R|11|C silent|CGC>CGG|R|11 silent|CGC>CGT|R|11 BDP1 B Double Prime 594.0 0 0 0 0 0.2948977615480199 P46678 0.0 0.0 52.86776416408179 50.0 1.0 no 12245 chrXIV_555085r 31263 essential YNL039W 40 - TCTACGCTGCCTTACTTTAG R|20|T R|20|K R|19|P R|19|H BDP1 B Double Prime 594.0 0 0 0 0 -0.011368825889582755 P46678 0.0 0.0 0.0 0.0 49.969549755025746 45.0 1.0 no 12246 chrXIV_555086r 31264 essential YNL039W 41 - CTCTACGCTGCCTTACTTTA R|20|T R|20|K R|19|P R|19|H BDP1 B Double Prime 594.0 0 0 0 0 0.9445698347801412 P46678 0.0 0.0 0.0 0.0 51.680294611461754 45.0 1.0 no 12247 chrXIV_555087r 31265 essential YNL039W 42 - GCTCTACGCTGCCTTACTTT R|20|T R|20|K A|21|P A|21|T BDP1 B Double Prime 594.0 0 0 0 0 0.18353170193324275 P46678 0.0 0.0 0.3088001310825348 0.9484710097312928 56.01113556329915 50.0 1.0 no 12248 chrXIV_555146r 31269 essential YNL039W 101 - TTTCGGGAATGAAAAGTTGA E|40|Q E|40|K BDP1 B Double Prime 594.0 0 0 0 0 0.1763136126604286 P46678 0.6105307340621948 0.9341749548912048 37.762694009761326 35.0 1.0 no 12249 chrXIV_555243r 31270 essential YNL039W 198 - GAGCGTTCTCCAACTAGCGA R|72|P R|72|H BDP1 B Double Prime 594.0 0 1 0 0 1.0587044615010746 P46678 0.26231977343559265 0.13150551915168762 53.186977230690964 55.00000000000001 1.0 no 12250 chrXIV_555350r 31277 essential YNL039W 305 - CTTCTATAACGTCTGCTTTG E|108|Q E|108|K BDP1 B Double Prime 594.0 0 0 0 0 0.6022877513920961 P46678 0.6102682948112488 0.9682557582855223 44.461487773301776 40.0 1.0 no 12251 chrXIV_555352r 31278 essential YNL039W 307 - ATCTTCTATAACGTCTGCTT D|109|H D|109|N E|108|Q E|108|K BDP1 B Double Prime 594.0 0 0 0 0 0.009141841139008159 P46678 0.14177365601062775 0.4972959458827973 0.6102682948112488 0.9682557582855223 45.2036013279565 35.0 1.0 no 12252 chrXIV_555351r 31279 essential YNL039W 306 - TCTTCTATAACGTCTGCTTT D|109|H D|109|N E|108|Q E|108|K BDP1 B Double Prime 594.0 0 0 0 0 0.7344636678470388 P46678 0.14177365601062775 0.4972959458827973 0.6102682948112488 0.9682557582855223 45.481402397472436 35.0 1.0 no 12253 chrXIV_555704 31289 essential YNL039W 656 + TACGGCAATGACCGATTCTT T|220|R T|220|M A|221|G A|221|V BDP1 B Double Prime 594.0 0 0 0 0 0.4150201802399184 P46678 0.23415330052375796 0.1413373053073883 0.4461798369884491 0.18938396871089933 47.18358107073891 45.0 1.0 no 12254 chrXIV_556014r 31290 essential YNL039W 969 - TCTTTAGTCAATGAGTGTAG E|330|Q E|330|K BDP1 B Double Prime 594.0 0 0 0 0 1.1871860541512842 P46678 0.0 0.0 40.82298994167803 35.0 1.0 no 12255 chrXIV_556134 31293 essential YNL039W 1086 + CAACTGAAGCTTAACCCTGA L|364|V silent|CTG>TTG|L|364 BDP1 B Double Prime 594.0 0 0 0 0 -0.2442255987543573 P46678 0.1436566561460495 45.732215736306046 45.0 1.0 no 12256 chrXIV_556142 31294 essential YNL039W 1094 + GCTTAACCCTGATGGTACTA L|366|V L|366|F N|367|K silent|AAC>AAT|N|367 BDP1 B Double Prime 594.0 0 0 0 0 0.5077006062841233 P46678 0.2188934683799744 0.039573684334754944 0.64593106508255 50.01311191652889 45.0 1.0 no 12257 chrXIV_556252 31295 essential YNL039W 1204 + TTGCCAATCTTTATAATTAC A|403|G A|403|V silent|GCC>GCG|A|403 silent|GCC>GCT|A|403 BDP1 B Double Prime 594.0 0 0 0 0 0.25658684977578144 P46678 0.06684311479330063 0.032804161310195916 37.822844622976326 25.0 1.0 no 12258 chrXIV_556302r 31298 essential YNL039W 1257 - ATCATTTCTTCCACAGTCCA M|425|I M|425|I BDP1 B Double Prime 594.0 0 0 0 0 -0.027532833078676072 P46678 0.2569239139556885 0.2569239139556885 52.105656745317724 40.0 1.0 no 12259 chrXIV_556301r 31299 essential YNL039W 1256 - TCATTTCTTCCACAGTCCAC M|425|I M|425|I E|424|Q E|424|K BDP1 B Double Prime 594.0 0 0 0 0 0.6968638464963708 P46678 0.2569239139556885 0.2569239139556885 0.0 0.0 52.62174911517553 45.0 1.0 no 12260 chrXIV_556331 31301 essential YNL039W 1283 + CTACAAGGCGCTTTCTATGT Y|429|* silent|TAC>TAT|Y|429 BDP1 B Double Prime 594.0 0 0 0 0 -1.9184973609350031 P46678 48.830904328842 45.0 1.0 no 12261 chrXIV_556332 31302 essential YNL039W 1284 + TACAAGGCGCTTTCTATGTG Y|429|* silent|TAC>TAT|Y|429 BDP1 B Double Prime 594.0 0 0 0 0 -2.205511446615738 P46678 46.99589005776869 45.0 1.0 yes 12262 chrXIV_556333 31303 essential YNL039W 1285 + ACAAGGCGCTTTCTATGTGG Y|429|* silent|TAC>TAT|Y|429 A|431|G A|431|V BDP1 B Double Prime 594.0 0 0 0 0 -2.8836665620006343 P46678 0.04285898432135582 0.01464034616947174 49.93300831517935 50.0 1.0 yes 12263 chrXIV_557313 31305 essential YNL038W 293 + TTTCCAGATCTTAATTATAA F|99|L silent|TTC>TTT|F|99 Q|100|E Q|100|* 0 0 0 0 0.7384324123976023 P53961 0.9387490153312684 0.9590039849281312 0.6295399069786072 0.5570458769798279 35.89583966368252 20.0 1.0 no 12264 chrXIV_557345r 31306 essential YNL038W 328 - CACAAGTATAATTGTACCTA V|116|L V|116|M 0 0 0 0 0.5366174145574035 P53961 0.9539830088615416 0.9587630033493042 0.4758615493774414 0.06904865801334381 38.66487249348757 30.0 1.0 no 12265 chrXIV_557413 31309 essential YNL038W 393 + CTACAGCTGTCCAGAGTGAA Q|133|E Q|133|* L|134|V silent|CTG>TTG|L|134 0 0 0 0 0.4424690040720032 P53961 0.9590039849281312 0.9512209892272948 0.17740386724472046 0.9232890009880066 50.184335319777794 50.0 1.0 no 12266 chrXIV_557449r 31311 essential YNL038W 432 - AACTTCCGATTCCATTGTTG K|150|N silent|AAG>AAA|K|150 silent|CGG>CGC|R|149 silent|CGG>CGA|R|149 0 0 0 0 -0.7205546083574271 P53961 0.9355990290641784 0.3494683504104614 46.8246178550359 40.0 1.0 no 12267 chrXIV_559858 31314 essential YNL036W 44 + CTCAAACCTACAAGATATCT S|16|* S|16|L N|17|K silent|AAC>AAT|N|17 NCE103 NonClassical Export 221.0 0 0 0 0 -0.7915448158685336 P53615 0.9298099875450134 0.9439849853515624 0.06300467252731322 0.8022856116294861 -0.16990000009536746 1.6946299076080322 39.85995404931293 35.0 1.0 no 12268 chrXIV_559875 31315 essential YNL036W 61 + TCTTGGCCGCCAATGCCAAA I|21|M silent|ATC>ATT|I|21 A|23|G A|23|V NCE103 NonClassical Export 221.0 0 0 0 0 0.4993939153710557 P53615 0.9598389863967896 0.9484469890594482 0.9504740238189696 0.09732551872730257 0.3295789062976837 0.32623136043548584 -0.5402399897575378 0.777999997138977 0.682200014591217 -0.7171000242233276 0.977999985218048 1.0037599802017212 0.3841400146484375 55.00202605247961 55.00000000000001 1.0 no 12269 chrXIV_559930 31319 essential YNL036W 116 + GTTCCCAGATCACAATGCGA F|40|L silent|TTC>TTT|F|40 P|41|A P|41|S NCE103 NonClassical Export 221.0 0 0 0 0 -0.21627424020417624 P53615 0.9387490153312684 0.9562489986419678 0.9498909711837769 0.0 0.7322762608528137 0.8092529773712158 1.752900004386902 1.8077800273895264 1.5071699619293213 51.54685588515292 50.0 1.0 no 12270 chrXIV_560025r 31322 essential YNL036W 214 - TTTCCAAGTGAACACTTCGC W|77|C W|77|* W|77|S W|77|* NCE103 NonClassical Export 221.0 0 0 0 0 -0.9440360510269236 P53615 0.8858469724655151 0.8858469724655151 0.1464276909828186 0.32509008049964905 2.89542007446289 3.6910800933837886 2.6545000076293945 3.3097400665283203 2.881969928741455 3.798870086669922 46.71057177751538 45.0 1.0 no 12271 chrXIV_560053 31323 essential YNL036W 239 + TGCTAACATATGTCACTCAG A|81|G A|81|V N|82|K silent|AAC>AAT|N|82 NCE103 NonClassical Export 221.0 0 0 0 0 0.26873202487801273 P53615 0.9484469890594482 0.9504740238189696 0.9439849853515624 0.0 0.0 0.0 -0.03778000175952912 0.6190199851989746 4.722280025482178 -0.6239799857139587 0.5983600020408629 43.220934117055435 40.0 1.0 no 12272 chrXIV_560169 31325 essential YNL036W 355 + AGACATGTTTAACTAACCAA T|120|R T|120|I NCE103 NonClassical Export 221.0 0 1 0 0 1.050974422867183 P53615 0.9476869702339172 0.9472420215606691 0.011015856638550758 0.008774636313319206 -0.2831400036811829 -1.433940052986145 -0.15604999661445618 -1.76951003074646 37.92974987879222 30.0 1.0 no 12273 chrXIV_560170 31326 essential YNL036W 356 + GACATGTTTAACTAACCAAA T|120|R T|120|I NCE103 NonClassical Export 221.0 0 1 0 0 0.8328917086412375 P53615 0.9476869702339172 0.9472420215606691 0.011015856638550758 0.008774636313319206 -0.2831400036811829 -1.433940052986145 -0.15604999661445618 -1.76951003074646 36.686411737486246 30.0 1.0 no 12274 chrXIV_560257r 31327 essential YNL036W 446 - TCAAATTTTGTGACTCTTCA L|155|F silent|TTG>TTA|L|155 NCE103 NonClassical Export 221.0 0 0 0 0 0.4567607488774622 P53615 0.9587849974632264 0.5567024946212769 4.654699802398682 6.780580043792725 40.52536351172438 30.0 1.0 no 12275 chrXIV_560281r 31328 essential YNL036W 470 - TTTCACGTTGCGTTTTCAAA E|163|Q E|163|K R|162|P R|162|H NCE103 NonClassical Export 221.0 0 0 0 0 0.33849735135457176 P53615 0.956179976463318 0.9475290179252625 0.9099509716033936 0.9570810198783876 0.58098965883255 0.8990444540977478 0.2848300635814667 0.16743147373199466 0.7553200125694275 0.9557600021362304 -0.6612600088119507 0.4184600114822388 43.97076637085331 35.0 1.0 no 12276 chrXIV_581965r 31329 essential YNL026W 48 - CTCTCATTGAAAATTGGCAT E|22|D silent|GAG>GAA|E|22 E|22|Q E|22|K SAM50 Sorting and Assembly Machinery 484.0 0 0 0 0 0.4103705799859874 P53969 0.9933249950408936 1.0004899501800537 0.9891330003738404 0.11697159707546236 0.4924638271331787 0.18601107597351074 40.81603664322563 35.0 1.0 no 12277 chrXIV_581964r 31330 essential YNL026W 47 - TCTCATTGAAAATTGGCATC E|22|Q E|22|K E|22|D silent|GAG>GAA|E|22 SAM50 Sorting and Assembly Machinery 484.0 0 0 0 0 0.4400402970759792 P53969 1.0004899501800537 0.9891330003738404 0.9933249950408936 0.4924638271331787 0.18601107597351074 0.11697159707546236 39.93399886285568 35.0 1.0 no 12278 chrXIV_581988 31331 essential YNL026W 68 + TTCTACTTTAAAGCCAATTA S|24|C S|24|F T|25|S T|25|I SAM50 Sorting and Assembly Machinery 484.0 0 0 0 0 1.13066445044578 P53969 0.9879119992256165 0.9685909748077391 0.9913139939308168 0.9893620014190674 0.05927007645368576 0.1460096389055252 0.8317493796348572 0.19710692763328552 38.251596338144964 25.0 1.0 no 12279 chrXIV_582001r 31332 essential YNL026W 84 - ACTACACCCGCAACCCTAAT V|35|L V|35|I V|34|L V|34|I SAM50 Sorting and Assembly Machinery 484.0 0 0 0 0 -1.9880612730091047 P53969 0.9940739870071412 1.0010499954223633 0.924390971660614 0.9320600032806396 0.6856445074081421 0.7892434597015381 0.20363199710845947 0.44191160798072815 52.21850653707504 50.0 1.0 no 12280 chrXIV_582042 31334 essential YNL026W 122 + TATCGACCCTAGCGTACTAC I|42|M silent|ATC>ATT|I|42 D|43|E silent|GAC>GAT|D|43 SAM50 Sorting and Assembly Machinery 484.0 0 0 0 0 -0.11472718828824766 P53969 1.0027899742126465 0.9954699873924256 0.012760992161929607 0.2133099734783173 50.299325773277424 50.0 1.0 no 12281 chrXIV_582092r 31335 essential YNL026W 175 - CACTAGCTGCCCCAAAGTAA V|65|L V|65|M Q|63|H silent|CAG>CAA|Q|63 SAM50 Sorting and Assembly Machinery 484.0 0 0 0 0 -0.1334833730640882 P53969 0.9940739870071412 1.0025099515914917 1.0006899833679201 0.7239531874656677 0.2372385114431381 0.160429909825325 51.20598764099873 50.0 1.0 no 12282 chrXIV_582161r 31336 essential YNL026W 244 - AAACGACTGTTTGGCGTTCA silent|TCG>TCC|S|87 silent|TCG>TCA|S|87 Q|86|H silent|CAG>CAA|Q|86 SAM50 Sorting and Assembly Machinery 484.0 0 0 0 0 0.13411720803122362 P53969 1.0006899833679201 0.1720525473356247 46.59646490208991 45.0 1.0 no 12283 chrXIV_582172 31337 essential YNL026W 252 + AAACAGTCGTTTCACTTCCA Q|86|E Q|86|* SAM50 Sorting and Assembly Machinery 484.0 0 0 0 0 -1.321023324459269 P53969 1.0026899576187134 0.6934547424316406 46.722879127516755 40.0 1.0 no 12284 chrXIV_582274r 31338 essential YNL026W 357 - TTCGCTGTAAACGTTTTAGG silent|GCG>GCC|A|125 silent|GCG>GCA|A|125 A|125|P A|125|T SAM50 Sorting and Assembly Machinery 484.0 0 0 0 0 -0.27976859900026024 P53969 1.0011199712753296 0.9935200214385986 0.0 0.0 43.05275635793736 40.0 1.0 no 12285 chrXIV_582463r 31341 essential YNL026W 546 - TTCAAGTTTAGAATTGATTG L|188|F silent|TTG>TTA|L|188 SAM50 Sorting and Assembly Machinery 484.0 0 0 0 0 0.9631102194238128 P53969 0.9229249954223632 0.5844407677650452 34.22016341154415 25.0 1.0 no 12286 chrXIV_582464r 31342 essential YNL026W 547 - TTTCAAGTTTAGAATTGATT L|188|F silent|TTG>TTA|L|188 SAM50 Sorting and Assembly Machinery 484.0 0 0 0 0 -0.1314212774371723 P53969 0.9229249954223632 0.5844407677650452 34.40145470183751 20.0 1.0 no 12287 chrXIV_582661 31346 essential YNL026W 741 + TCCACTAAGATATGTTCACA silent|TCC>TCG|S|248 silent|TCC>TCT|S|248 S|248|C S|248|F SAM50 Sorting and Assembly Machinery 484.0 0 0 0 0 -0.4898246639622914 P53969 0.9634199738502502 0.9436050057411194 0.01308099739253521 0.007916043512523174 43.09485307051159 35.0 1.0 no 12288 chrXIV_582662r 31347 essential YNL026W 745 - GCCTTGTGAACATATCTTAG G|255|R G|255|S G|255|A G|255|D SAM50 Sorting and Assembly Machinery 484.0 0 0 0 0 0.5693435690120483 P53969 0.9477360248565674 0.9668909907341005 0.9656509757041932 0.9535760283470154 0.6815429329872131 0.976287007331848 0.9623239040374756 0.7477399110794067 44.77533150328036 40.0 1.0 no 12289 chrXIV_582796r 31349 essential YNL026W 879 - TTCAACATCGAACCCTTAGT L|299|F silent|TTG>TTA|L|299 M|298|I M|298|I SAM50 Sorting and Assembly Machinery 484.0 0 0 0 0 -0.8686786367416672 P53969 0.9683070182800292 0.9643309712409972 0.9643309712409972 1.0 0.16603516042232513 0.16603516042232513 46.070906412015226 40.0 1.0 no 12290 chrXIV_582795r 31350 essential YNL026W 878 - TCAACATCGAACCCTTAGTA L|299|F silent|TTG>TTA|L|299 M|298|I M|298|I SAM50 Sorting and Assembly Machinery 484.0 0 0 0 0 0.038591902973943895 P53969 0.9683070182800292 0.9643309712409972 0.9643309712409972 1.0 0.16603516042232513 0.16603516042232513 45.30567755819453 40.0 1.0 no 12291 chrXIV_582857r 31351 essential YNL026W 940 - TACACTGTTCAATTCTAATT V|320|L V|320|I S|319|T S|319|N SAM50 Sorting and Assembly Machinery 484.0 0 1 0 0 0.3025144801743309 P53969 0.9612960219383241 0.9689649939537048 0.9669449925422668 0.9709960222244264 0.4763567447662354 0.5541930198669434 0.7312442660331726 0.6101521849632263 37.45768733872609 25.0 1.0 no 12292 chrXIV_582950r 31352 essential YNL026W 1033 - TACAGGCAAGGATTGTTGTG V|351|L V|351|I L|349|F silent|TTG>TTA|L|349 SAM50 Sorting and Assembly Machinery 484.0 0 0 0 0 1.035510829633521 P53969 0.9580050110816956 0.9656739830970764 0.9690459966659546 0.77159184217453 1.0 0.7025980949401855 45.57933520952116 45.0 1.0 no 12293 chrXIV_582967r 31353 essential YNL026W 1050 - AACTTATCACATATATGTAC K|356|N silent|AAG>AAA|K|356 SAM50 Sorting and Assembly Machinery 484.0 0 0 0 0 -0.5868470713124025 P53969 0.95727801322937 0.010102614760398865 34.95097535089485 25.0 1.0 no 12294 chrXIV_618803r 31354 essential YNL007C 740 + GACTTTGCAGTTTGTCATCC T|248|S T|248|I SIS1 SIt4 Suppressor 352.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.4833137084511132 P25294 0.4327031970024109 0.043692681938409805 -1.521299958229065 -0.4183000028133392 51.45299117417039 45.0 0.0 no 12295 chrXIV_618923 31358 essential YNL007C 623 - TCTTTTCAGAGGCCCCATGT K|214|N silent|AAG>AAA|K|214 E|213|Q E|213|K SIS1 SIt4 Suppressor 352.0 0 0 0 0 -0.14637610845446022 P25294 0.3148378431797028 0.32134997844696045 0.557631254196167 0.1945600062608719 0.19915999472141266 1.0898400545120241 0.5091999769210815 58.225765565618474 50.0 0.0 no 12296 chrXIV_619031r 31359 essential YNL007C 512 + AAGCTCTCCCACGTATCCAG S|172|R silent|AGC>AGT|S|172 S|173|C S|173|F SIS1 SIt4 Suppressor 352.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.18572468440698647 P25294 0.5435297489166261 0.04185038432478905 0.04664869979023933 55.58269345314386 55.00000000000001 0.0 no 12297 chrXIV_619096 31361 essential YNL007C 450 - TGCATTCCTCCCATTCCTCC M|156|I M|156|I G|155|A G|155|E SIS1 SIt4 Suppressor 352.0 0 0 0 0 0.4378621166754742 P25294 0.21261011064052585 0.21261011064052585 0.8039579391479492 1.0 62.64893394703432 55.00000000000001 0.0 no 12298 chrXIV_619138r 31366 essential YNL007C 405 + TCTAGTTATCCATCTGGCGG S|136|C S|136|F SIS1 SIt4 Suppressor 352.0 0 0 0 0 0.7848213021810666 P25294 0.08997499942779541 0.08820942044258118 52.616774357535064 50.0 0.0 no 12299 chrXIV_619141r 31367 essential YNL007C 402 + TTCTCTAGTTATCCATCTGG F|135|L silent|TTC>TTT|F|135 S|136|C S|136|F SIS1 SIt4 Suppressor 352.0 0 0 0 0 0.4443356051395593 P25294 0.6905805468559265 0.08997499942779541 0.08820942044258118 48.498030623147486 40.0 0.0 no 12300 chrXIV_619175 31368 essential YNL007C 371 - TGTCATCAGCACCACCGAAT D|130|H D|130|N D|129|H D|129|N SIS1 SIt4 Suppressor 352.0 0 0 0 0 0.4667574655868829 P25294 0.219430074095726 0.5850617289543152 0.17042018473148346 0.7478184103965759 51.75424507032795 50.0 0.0 no 12301 chrXIV_619432 31377 essential YNL007C 114 - AACTTTTCTGTGTCACCTGT K|44|N silent|AAG>AAA|K|44 SIS1 SIt4 Suppressor 352.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.08255521426699072 P25294 0.011344368569552898 0.948319971561432 49.81785496332236 40.0 0.0 no 12302 chrXIV_619447r 31378 essential YNL007C 96 + TATCATCCAGATAAGCCAAC H|34|D H|34|Y P|35|A P|35|S SIS1 SIt4 Suppressor 352.0 0 1 0 0 -5.505291907947884 P25294 0.0 0.0 0.0 0.0 0.7679799795150757 -0.935699999332428 2.3727400302886963 2.8575599193573 0.3326449990272522 0.1362610012292862 44.10944322553729 40.0 0.0 yes 12303 chrXIV_620096 31380 essential YNL006W 29 + TGACCACACAATAAGATTTT D|11|E silent|GAC>GAT|D|11 H|12|D H|12|Y 0 0 0 0 -0.04469158664148168 P41318 0.001461696345359087 0.3647956252098084 0.3605351150035858 38.42820961990333 30.0 1.0 no 12304 chrXIV_620212 31382 essential YNL006W 145 + CAGCAGGCCATCAAAACGTA A|50|G A|50|V 0 0 0 0 -0.7856867629407588 P41318 1.0 0.046586107462644584 2.2070000171661377 3.9772000312805176 47.90847643738692 50.0 1.0 no 12305 chrXIV_620227 31383 essential YNL006W 160 + ACGTACGGCTTTATGACATT N|54|K silent|AAC>AAT|N|54 R|56|G R|56|W 0 0 0 0 -0.3832354062976293 P41318 0.006551837548613547 0.003504353575408459 0.014779298566281797 45.5573730132781 40.0 1.0 no 12306 chrXIV_620259r 31384 essential YNL006W 195 - TCAAAGGATGCTACTGGATT E|72|Q E|72|K 0 0 0 0 -0.4301097985097164 P41318 0.4352058172225952 0.6068423390388489 43.20517697088661 40.0 1.0 no 12307 chrXIV_620262 31386 essential YNL006W 195 + AATCCAGTAGCATCCTTTGA P|67|A P|67|S P|67|R P|67|L 0 0 0 0 0.029313531600439924 P41318 0.7507023215293884 0.7247969508171082 0.5194404125213623 0.31719133257865906 49.337517711822606 40.0 1.0 no 12308 chrXIV_620359r 31391 essential YNL006W 295 - ACGCACATCCCAAACTTTAA silent|GTG>GTC|V|104 silent|GTG>GTA|V|104 R|105|P R|105|H 0 0 0 0 -0.2374330136821789 P41318 0.2557112276554108 0.13369114696979525 45.194930492285216 40.0 1.0 no 12309 chrXIV_620430 31392 essential YNL006W 363 + GTCGTAATTCATCCTAACCA silent|GTC>GTG|V|122 silent|GTC>GTT|V|122 0 0 0 0 1.1083588706448433 P41318 47.044213389548425 40.0 1.0 no 12310 chrXIV_620546 31395 essential YNL006W 479 + CTCTCTCCAGTCTTTATCTA S|161|C S|161|F L|162|V L|162|F 0 0 0 0 -0.39669608327723904 P41318 0.18644337356090546 0.6126766800880432 1.0 0.01900141686201096 0.1022000014781952 0.9088000059127808 51.117212246957706 40.0 1.0 no 12311 chrXIV_620556 31397 essential YNL006W 489 + TCTTTATCTATGGCAAGTGA S|164|C S|164|F 0 0 0 0 0.7548677520410548 P41318 0.033486567437648766 0.001756737125106156 43.82963896884093 35.0 1.0 no 12312 chrXIV_620642 31398 essential YNL006W 575 + TGACGCATCCCATCTAAAAC D|193|E silent|GAC>GAT|D|193 A|194|G A|194|V 0 0 0 0 0.0081665544145275 P41318 0.16350047290325165 0.13547071814537048 0.3765661418437958 0.4765999913215637 0.5983999967575073 45.11712646329311 45.0 1.0 no 12313 chrXIV_620661r 31399 essential YNL006W 597 - TGCGCTCTGAATTTTGTTAC silent|GCG>GCC|A|205 silent|GCG>GCA|A|205 A|205|P A|205|T 0 0 0 0 0.6152154979795655 P41318 0.002728437539190054 0.002242242218926549 3.510200023651123 2.026000022888184 45.511125699594686 40.0 1.0 no 12314 chrXIV_620711 31400 essential YNL006W 644 + ATCATCTGATGTAAAACATT S|216|* S|216|L S|217|C S|217|F 0 0 0 0 0.17670390100372296 P41318 0.011234707199037077 0.001362392911687493 0.01647370122373104 0.5440000295639038 0.14100000262260434 35.269121348599356 25.0 1.0 no 12315 chrXIV_626451 31401 essential YNL002C 672 - TCATTAAGAACTATTTCGTG D|231|H D|231|N RLP7 Ribosomal-Like Protein 322.0 0 0 0 0 0.4019939536061947 P40693 0.9486550092697144 0.956179976463318 0.01698465086519718 0.3880635797977448 36.630881524763886 30.0 0.0 no 12316 chrXIV_626509 31403 essential YNL002C 614 - CTCTCTTTTGAATCAAGGAA R|211|T R|211|K K|210|N silent|AAG>AAA|K|210 RLP7 Ribosomal-Like Protein 322.0 0 0 0 0 -0.5844838612606691 P40693 0.932735025882721 0.955805003643036 0.9355990290641784 0.0 0.0 0.00949933845549822 40.07672828887826 35.0 0.0 no 12317 chrXIV_626547 31404 essential YNL002C 576 - GGCTTGCCAATCACTACGTA K|198|N silent|AAG>AAA|K|198 G|197|A G|197|D RLP7 Ribosomal-Like Protein 322.0 0 0 0 0 -0.1458330127215476 P40693 0.9355990290641784 0.9499930143356324 0.9446240067481996 0.1156524494290352 0.0 0.0 52.051909809099534 50.0 0.0 no 12318 chrXIV_626578r 31405 essential YNL002C 542 + AAACGTATATCCGTTGCTCA N|182|K silent|AAC>AAT|N|182 RLP7 Ribosomal-Like Protein 322.0 0 0 0 0 0.7470197675182743 P40693 0.9439849853515624 0.9760773777961732 45.789025692237495 40.0 0.0 no 12319 chrXIV_626855r 31408 essential YNL002C 265 + AAACGCAGCATATTGCATCT T|90|R T|90|M Q|91|E Q|91|* RLP7 Ribosomal-Like Protein 322.0 0 0 0 0 0.108728602581666 P40693 0.9476869702339172 0.9502379894256592 0.9590039849281312 0.4557620584964752 0.099757082760334 1.0 45.26536228729748 40.0 0.0 no 12320 chrXIV_634568 31410 essential YNR003C 710 - ACAAAGATCTGATATTTGAA L|243|F silent|TTG>TTA|L|243 RPC34 RNA Polymerase C 317.0 0 0 0 0 0.2446522437734338 P32910 0.0 33.464294868833754 25.0 0.0 no 12321 chrXIV_634631r 31411 essential YNR003C 644 + CTCTACCACACAAGAAATTT S|216|C S|216|F T|217|S T|217|I RPC34 RNA Polymerase C 317.0 0 0 0 0 -0.07474869957333273 P32910 0.08579334616661073 0.0537896454334259 0.5756356716156006 0.048004820942878716 39.97678778035481 35.0 0.0 no 12322 chrXIV_634717r 31414 essential YNR003C 558 + TCAGAGAACACCTTCCCTAA S|187|* S|187|L RPC34 RNA Polymerase C 317.0 0 0 0 0 -0.5697506325769148 P32910 0.20576541125774386 48.877907962053364 45.0 0.0 no 12323 chrXIV_634848 31420 essential YNR003C 430 - CAACATGTAGATTTTCCTTG M|149|I M|149|I RPC34 RNA Polymerase C 317.0 0 0 0 0 0.5704503431792196 P32910 0.0 0.0 41.698218600835155 35.0 0.0 no 12324 chrXIV_634789 31421 essential YNR003C 489 - AGCTCTCCATCTGTGAACCA E|169|D silent|GAG>GAA|E|169 E|169|Q E|169|K RPC34 RNA Polymerase C 317.0 0 0 0 0 -0.11840706658162722 P32910 0.0 0.0 0.0 54.49882903619283 50.0 0.0 no 12325 chrXIV_634849 31422 essential YNR003C 429 - AACATGTAGATTTTCCTTGT M|149|I M|149|I RPC34 RNA Polymerase C 317.0 0 0 0 0 0.7193424156611304 P32910 0.0 0.0 42.849444470399646 30.0 0.0 no 12326 chrXIV_634886 31423 essential YNR003C 392 - TAACACTCTTCACGTATCTT V|137|L V|137|I S|136|T S|136|N RPC34 RNA Polymerase C 317.0 0 0 0 0 0.2603368605602233 P32910 0.0757332295179367 0.7823182344436646 0.1461276262998581 0.06861665099859238 43.2323706351728 35.0 0.0 no 12327 chrXIV_634887 31424 essential YNR003C 391 - AACACTCTTCACGTATCTTT V|137|L V|137|I S|136|T S|136|N RPC34 RNA Polymerase C 317.0 0 0 0 0 0.1660359760164016 P32910 0.0757332295179367 0.7823182344436646 0.1461276262998581 0.06861665099859238 44.051353630146075 35.0 0.0 no 12328 chrXIV_635003r 31428 essential YNR003C 272 + ACTGGTATATTCTTATATCG L|92|V silent|CTG>TTG|L|92 RPC34 RNA Polymerase C 317.0 0 0 0 0 -0.09191684453434354 P32910 0.0515034981071949 39.610885455918954 30.0 0.0 no 12329 chrXIV_635127 31430 essential YNR003C 151 - GTCTAGCAATTCCTGTACAA D|57|H D|57|N L|55|F silent|TTG>TTA|L|55 RPC34 RNA Polymerase C 317.0 0 0 0 0 0.2651591640391431 P32910 0.06207066029310225 1.0 0.0 46.654153570111646 40.0 0.0 no 12330 chrXIV_635138r 31431 essential YNR003C 137 + AGACTTGATGTCCATTGTAC D|47|E silent|GAC>GAT|D|47 RPC34 RNA Polymerase C 317.0 0 0 0 0 0.8605145043303521 P32910 1.0 45.60079959280829 40.0 0.0 no 12331 chrXIV_635169r 31432 essential YNR003C 106 + TCCAAAAACAAATGGGAATC Q|37|E Q|37|* silent|CTC>CTG|L|36 silent|CTC>CTT|L|36 RPC34 RNA Polymerase C 317.0 0 0 0 0 -0.3218287652043895 P32910 0.5011728405952454 35.08169822167332 35.0 0.0 no 12332 chrXIV_635177r 31433 essential YNR003C 98 + GCAAGAACTCCAAAAACAAA Q|34|E Q|34|* RPC34 RNA Polymerase C 317.0 0 0 0 0 -0.6206077322230674 P32910 1.0 35.284932208143175 35.0 0.0 no 12333 chrXIV_635226 31434 essential YNR003C 52 - CGACATCATCTGGCTATGTA M|23|I M|23|I M|22|I M|22|I RPC34 RNA Polymerase C 317.0 0 0 0 0 -0.3674961197162966 P32910 0.9998997449874878 0.9998997449874878 0.2785930633544922 0.2785930633544922 47.80299681250705 45.0 0.0 no 12334 chrXIV_645089 31435 essential YNR011C 1842 - TCCAAAGACTTCCGTAATGT L|620|F silent|TTG>TTA|L|620 E|621|Q E|621|K PRP2 Pre-mRNA Processing 876.0 0 1 0 0 -0.6071807026654453 P20095 0.004099469631910324 0.02358703501522541 0.00724045606330037 45.10430203993264 40.0 0.0 no 12335 chrXIV_645113 31437 essential YNR011C 1818 - ATACTGGGCTTATCCATCAG S|612|T S|612|N PRP2 Pre-mRNA Processing 876.0 0 0 0 0 0.2447118780025086 P20095 0.05699362233281136 0.0037769251503050327 49.53195353430573 45.0 0.0 no 12336 chrXIV_645126r 31438 essential YNR011C 1802 + CCTAATAAAGTTTCCCCTGA L|602|V silent|CTA>TTA|L|602 PRP2 Pre-mRNA Processing 876.0 0 0 0 0 0.9263453955745024 P20095 0.003910612780600786 47.591784011181915 40.0 0.0 no 12337 chrXIV_645280 31440 essential YNR011C 1651 - CCCAACACGACCAGCCCTAC G|557|R G|557|R G|557|A G|557|E PRP2 Pre-mRNA Processing 876.0 0 0 0 0 0.18094404968695044 P20095 0.11707140505313872 0.11707140505313872 0.33662188053131104 0.04475127533078194 58.11882155980192 65.0 0.0 no 12338 chrXIV_645311 31445 essential YNR011C 1620 - TCAACTGAAGCTCTTGAGCA D|547|H D|547|N V|546|L V|546|I PRP2 Pre-mRNA Processing 876.0 0 0 0 0 -0.10558473387353667 P20095 0.024256519973278046 1.0 0.003062153235077858 0.0024717643391340967 46.799338175086746 45.0 0.0 no 12339 chrXIV_645571 31449 essential YNR011C 1360 - AGACATGATCTCCTCCAGTT M|459|I M|459|I PRP2 Pre-mRNA Processing 876.0 0 0 0 0 -0.24949437288006915 P20095 0.5595294237136841 0.5595294237136841 52.260085717669604 45.0 0.0 no 12340 chrXIV_645645r 31452 essential YNR011C 1283 + TCATACTACGCAAAGTTTAC H|429|D H|429|Y T|430|S T|430|I PRP2 Pre-mRNA Processing 876.0 0 0 0 0 0.2941598336384601 P20095 0.0 0.0 0.02479143068194389 0.4803731441497803 39.454185673232075 35.0 0.0 no 12341 chrXIV_645692 31453 essential YNR011C 1239 - GCATGTATATAGTTTGCCTC A|420|P A|420|T PRP2 Pre-mRNA Processing 876.0 0 0 0 0 -0.30973646329020066 P20095 0.0 0.0 48.71985447731299 40.0 0.0 no 12342 chrXIV_645708 31454 essential YNR011C 1223 - CCTCCGGCTGTAATGTGTAG E|414|Q E|414|K E|414|D silent|GAG>GAA|E|414 PRP2 Pre-mRNA Processing 876.0 0 0 0 0 0.19743677083219024 P20095 0.0 0.0 0.0 53.6990662500665 55.00000000000001 0.0 no 12343 chrXIV_645734 31456 essential YNR011C 1197 - TCTACAGGATATCTTCTCCC D|406|H D|406|N V|405|L V|405|I PRP2 Pre-mRNA Processing 876.0 0 0 0 0 -0.991533034288556 P20095 0.0032353769056499004 0.007220131810754538 0.0 0.0 51.24419415620923 45.0 0.0 no 12344 chrXIV_645858 31457 essential YNR011C 1073 - TATCTTTCAGCAAACCTATC D|364|H D|364|N PRP2 Pre-mRNA Processing 876.0 0 0 0 0 0.5863066664873902 P20095 0.00305849127471447 0.0055632502771914005 42.80285469811969 35.0 0.0 no 12345 chrXIV_645925 31458 essential YNR011C 1006 - ACAAGAATATTTGCTTAATT C|342|S C|342|Y PRP2 Pre-mRNA Processing 876.0 0 0 0 0 -0.5337153653030706 P20095 0.009151366539299488 0.002466195495799184 33.64852080987788 20.0 0.0 no 12346 chrXIV_645981r 31459 essential YNR011C 947 + AACGGTTCTAAAGTATATGA T|317|R T|317|M PRP2 Pre-mRNA Processing 876.0 0 0 0 0 -1.177874092403998 P20095 0.0 0.0 36.79649924306193 30.0 0.0 no 12347 chrXIV_645989 31460 essential YNR011C 942 - TACTTTAGAACCGTTTTATT K|320|N silent|AAG>AAA|K|320 PRP2 Pre-mRNA Processing 876.0 0 0 0 0 -0.3432423355072201 P20095 0.001900149276480079 39.33525875027783 25.0 0.0 no 12348 chrXIV_645990 31461 essential YNR011C 941 - ACTTTAGAACCGTTTTATTT K|320|N silent|AAG>AAA|K|320 PRP2 Pre-mRNA Processing 876.0 0 0 0 0 1.0527240194289529 P20095 0.001900149276480079 40.11406857023889 25.0 0.0 no 12349 chrXIV_646159 31464 essential YNR011C 772 - TCCATCTTCTACCAAATATT G|264|R G|264|R G|264|A G|264|E PRP2 Pre-mRNA Processing 876.0 0 0 0 0 0.6044607623348681 P20095 0.0 0.0 0.0 0.0 42.98727590128278 30.0 0.0 no 12350 chrXIV_646170r 31465 essential YNR011C 758 + CACACAGTTACCCCAATATT T|254|R T|254|I Q|255|E Q|255|* PRP2 Pre-mRNA Processing 876.0 0 0 0 0 -0.4414414192824266 P20095 0.0 0.0 0.0 47.622858959885825 40.0 0.0 no 12351 chrXIV_646259 31466 essential YNR011C 672 - TCATCCTTGTATTGATGTAC E|231|Q E|231|K D|230|H D|230|N PRP2 Pre-mRNA Processing 876.0 0 0 0 0 0.5012420266760639 P20095 0.4941999316215515 0.07576281577348709 0.048106618225574486 0.018947508186101917 44.244551842668784 35.0 0.0 no 12352 chrXIV_646452 31468 essential YNR011C 479 - CTTCCAATGTTATATCATCA E|166|Q E|166|K L|165|F silent|TTG>TTA|L|165 PRP2 Pre-mRNA Processing 876.0 0 0 0 0 -0.31579651443728896 P20095 0.5592008233070374 0.8824830055236816 0.055269449949264526 42.14446725972834 30.0 0.0 no 12353 chrXIV_646491r 31471 essential YNR011C 437 + ACAACAATTGCGAAATGCTA Q|147|E Q|147|* Q|148|E Q|148|* PRP2 Pre-mRNA Processing 876.0 0 0 0 0 -2.297875216452588 P20095 1.0 0.13287556171417236 38.72184097861373 35.0 0.0 yes 12354 chrXIV_646634r 31472 essential YNR011C 294 + ACTACAAAGAAGGGTCTACT T|99|S T|99|I T|100|R T|100|I PRP2 Pre-mRNA Processing 876.0 0 0 0 0 0.07689153955464179 P20095 0.4141256809234619 0.3943815529346466 0.3923547565937042 0.10515958070755003 41.338213779747036 40.0 0.0 no 12355 chrXIV_646724 31473 essential YNR011C 207 - CCTTTTAAATTGTTCTTTTC G|76|R G|76|R PRP2 Pre-mRNA Processing 876.0 0 0 0 0 0.4764955938512382 P20095 0.5155181288719177 0.5155181288719177 39.59688365239509 25.0 0.0 no 12356 chrXIV_646724r 31474 essential YNR011C 204 + CCAGAAAAGAACAATTTAAA P|69|R P|69|L PRP2 Pre-mRNA Processing 876.0 0 0 0 0 -0.2764502438694356 P20095 0.4835647940635681 0.2718127965927124 30.56734094261805 25.0 0.0 no 12357 chrXIV_656385r 31477 essential YNR016C 4967 + ATACTTAACAAGTGAAGGTA Y|1657|* silent|TAC>TAT|Y|1657 ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 0.7989455314904057 Q00955 36.19137448505626 30.0 0.0 no 12358 chrXIV_656390r 31478 essential YNR016C 4962 + TACTTATACTTAACAAGTGA Y|1655|* silent|TAC>TAT|Y|1655 ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 0.17528907273404046 Q00955 34.70366326608763 25.0 0.0 no 12359 chrXIV_656473 31480 essential YNR016C 4882 - CTCTTCAGCCATACCAATTC E|1634|Q E|1634|K E|1633|Q E|1633|K ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -0.5911918796044764 Q00955 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.0 0.0 0.06492149084806442 0.2600519359111786 -0.16339999437332153 0.07859999686479567 -0.4961999952793121 -0.25099998712539673 -0.09690000116825104 0.0070000067353248605 50.057437913461975 45.0 0.0 no 12360 chrXIV_656531r 31483 essential YNR016C 4821 + ACTGAATATGCTAGAAAGCG T|1608|S T|1608|I ACC1 Acetyl-CoA Carboxylase 2233.0 0 1 0 0 -0.938443179443314 Q00955 0.9491789937019348 0.9472420215606691 1.0 0.0027735168114304547 0.8636000156402588 0.24560000002384186 39.154771873762456 40.0 0.0 no 12361 chrXIV_656569 31484 essential YNR016C 4786 - TTCGTCTTCTTGTGGACCAA E|1602|Q E|1602|K D|1601|H D|1601|N ACC1 Acetyl-CoA Carboxylase 2233.0 0 1 0 0 0.9912616853385396 Q00955 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.6331759691238403 0.9098379611968994 0.0 0.0 0.2011999934911728 -0.2526000142097473 -0.05000000074505806 -0.5256000161170961 50.62808776716958 45.0 0.0 no 12362 chrXIV_656585r 31485 essential YNR016C 4767 + ACATTCAAGATCGGTTCCTT T|1590|R T|1590|I F|1591|L silent|TTC>TTT|F|1591 ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -1.439207607209848 Q00955 0.9476869702339172 0.9472420215606691 0.9387490153312684 0.0014418441569432616 0.0016270054038614035 0.059228159487247474 4.166999816894531 2.0032000541687007 1.5327999591827393 47.57590780931372 40.0 0.0 no 12363 chrXIV_656624 31486 essential YNR016C 4731 - ACAACAAATTGACGGCCTCT V|1584|L V|1584|I V|1583|L V|1583|I ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 0.1899473551134262 Q00955 0.9539830088615416 0.9574310183525084 0.9539830088615416 0.9574310183525084 0.39727815985679626 0.28951993584632874 0.013392731547355652 1.0 0.39579999446868896 0.22339999675750727 -0.08780000358819963 0.11540000140666963 45.70330523357313 45.0 0.0 no 12364 chrXIV_656616 31487 essential YNR016C 4739 - TAGCAACAACAACAAATTGA A|1586|P A|1586|T V|1585|L V|1585|I ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -1.2451083180333642 Q00955 0.9573720097541808 0.9523990154266356 0.9539830088615416 0.9574310183525084 0.027472672984004017 0.019403720274567604 0.017353309318423268 1.0 4.093800067901611 -0.4828000068664551 0.03060000017285347 -1.4428000450134275 34.206066879002265 30.0 0.0 no 12365 chrXIV_656656 31488 essential YNR016C 4699 - AGTCTTTACAGTAATCTTAA K|1572|N silent|AAG>AAA|K|1572 ACC1 Acetyl-CoA Carboxylase 2233.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.23267841526933755 Q00955 0.9355990290641784 0.08496938645839691 0.5491999983787537 37.449897294139646 25.0 0.0 no 12366 chrXIV_656677 31489 essential YNR016C 4678 - GGCAACCATACCAATAGCGT A|1566|P A|1566|T V|1565|L V|1565|I ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -1.5481538899820235 Q00955 0.9573720097541808 0.9523990154266356 0.9539830088615416 0.9574310183525084 0.01520316209644079 0.010481168515980244 0.0 0.0 3.2827999591827397 1.367799997329712 1.8691999912261963 0.2689999938011169 50.5404787350937 50.0 0.0 no 12367 chrXIV_656684 31490 essential YNR016C 4671 - ATACCAATAGCGTTGGCACC G|1563|A G|1563|D G|1563|R G|1563|S ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -0.9137233734800936 Q00955 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.017151707783341408 0.0042310645803809175 0.001773210125975311 0.018732614815235138 0.5103999972343445 10.974200248718262 16.88960075378418 3.0480000972747803 51.166515262924975 50.0 0.0 no 12368 chrXIV_656806r 31495 essential YNR016C 4546 + GCCAAGCATCGTCATCCCAA Q|1517|E Q|1517|* silent|CGC>CGG|R|1516 silent|CGC>CGT|R|1516 ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -0.4152454305724585 Q00955 0.9590039849281312 0.11874794214963913 0.0697999969124794 56.202787018359224 55.00000000000001 0.0 no 12369 chrXIV_656904r 31498 essential YNR016C 4448 + TGCTACTCCTTACCCTGTTA A|1484|G A|1484|V T|1485|S T|1485|I ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -0.03318502423174785 Q00955 0.9484469890594482 0.9504740238189696 0.9491789937019348 0.9472420215606691 0.12184574455022812 0.02643280848860741 0.12527474761009216 0.09749459475278854 55.07147366267316 45.0 0.0 no 12370 chrXIV_656980 31502 essential YNR016C 4375 - ACCTTTTGCGTTCTTGACTT G|1465|R G|1465|S G|1465|A G|1465|D ACC1 Acetyl-CoA Carboxylase 2233.0 0 1 0 0 0.16049879327353878 Q00955 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.006330890115350485 0.038164351135492325 0.13887962698936462 0.012867297045886515 50.63948330317209 40.0 0.0 no 12371 chrXIV_657071r 31505 essential YNR016C 4281 + ATCATCAAAGATCCTCAAAC I|1428|M silent|ATC>ATT|I|1428 I|1429|M silent|ATC>ATT|I|1429 ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -0.3541250537346519 Q00955 0.9598389863967896 0.9598389863967896 0.18274828791618347 0.0195942185819149 38.70727933524501 35.0 0.0 no 12372 chrXIV_657393 31509 essential YNR016C 3962 - TACTAACAGCTTCGTAGACA S|1327|T S|1327|N V|1326|L V|1326|I ACC1 Acetyl-CoA Carboxylase 2233.0 0 1 0 0 0.10482893464848464 Q00955 0.9512869715690612 0.9536849856376648 0.9539830088615416 0.9574310183525084 0.030044836923480037 0.02093043178319931 0.2643474340438843 0.31320664286613464 43.63799866999432 40.0 0.0 no 12373 chrXIV_657419 31510 essential YNR016C 3936 - TTTCTATTATCAGTGAAAAT R|1318|T R|1318|K ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -0.4052008895083442 Q00955 0.932735025882721 0.955805003643036 0.1479061245918274 1.0 33.32707693607921 20.0 0.0 no 12374 chrXIV_657459 31511 essential YNR016C 3896 - ACAATCTTCCTAATTCCAGT L|1305|F silent|TTG>TTA|L|1305 R|1304|T R|1304|K ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 0.4455636719694988 Q00955 0.9587849974632264 0.932735025882721 0.955805003643036 0.015113439410924913 0.005326236132532358 0.14435313642024994 46.07106676102677 35.0 0.0 no 12375 chrXIV_657463 31512 essential YNR016C 3892 - TCTTCCTAATTCCAGTTGGA R|1304|T R|1304|K G|1303|A G|1303|E ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 0.1095625363606195 Q00955 0.932735025882721 0.955805003643036 0.9499930143356324 0.9438679814338684 0.005326236132532358 0.14435313642024994 0.8091555237770081 1.0 49.8584855177487 40.0 0.0 no 12376 chrXIV_657492r 31515 essential YNR016C 3860 + AACAATTCGTCACATTGAGC T|1288|R T|1288|I ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 0.1574571763433514 Q00955 0.9476869702339172 0.9472420215606691 0.171610489487648 1.0 42.246441474538024 40.0 0.0 no 12377 chrXIV_657536r 31517 essential YNR016C 3816 + CCAAAGTATTATACTTTTAA P|1273|R P|1273|L ACC1 Acetyl-CoA Carboxylase 2233.0 0 1 0 0 0.34179522549129315 Q00955 0.9432820081710817 0.9430609941482544 0.0037879971787333493 0.009632017463445663 34.051505145459146 20.0 0.0 no 12378 chrXIV_657737r 31522 essential YNR016C 3615 + GGACCTGCTCCTGATCGTTC P|1207|A P|1207|S P|1207|R P|1207|L ACC1 Acetyl-CoA Carboxylase 2233.0 0 1 0 0 -0.5673192583461907 Q00955 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.603105366230011 0.5485899448394775 0.4320961534976959 0.668289065361023 58.45002515922693 60.0 0.0 no 12379 chrXIV_657758r 31523 essential YNR016C 3594 + CGTCACCAATCTTCTTCTAA H|1200|D H|1200|Y H|1200|Q silent|CAC>CAT|H|1200 ACC1 Acetyl-CoA Carboxylase 2233.0 0 1 0 0 0.6382456391263991 Q00955 0.9473130106925964 0.9489949941635132 0.9588389992713928 0.5271918773651123 1.0 0.5921628475189209 46.176478851899844 40.0 0.0 no 12380 chrXIV_657842 31524 essential YNR016C 3513 - ATCAAAATACCTTCTCTTAA L|1177|F silent|TTG>TTA|L|1177 ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 0.4602330504719567 Q00955 0.9587849974632264 0.01861755922436714 36.98684234289834 25.0 0.0 no 12381 chrXIV_657923 31527 essential YNR016C 3432 - CCCATTTTAGATTTAACAGT M|1150|I M|1150|I G|1151|R G|1151|S ACC1 Acetyl-CoA Carboxylase 2233.0 0 1 0 0 -0.05923209474282451 Q00955 0.9553959965705872 0.9553959965705872 0.941340982913971 0.951104998588562 0.3869320452213288 0.3869320452213288 0.5623224377632141 0.7964028716087341 42.545166676227545 30.0 0.0 no 12382 chrXIV_658028r 31528 essential YNR016C 3324 + GCTTATCGTGCTTACACCAT A|1109|G A|1109|V R|1111|G R|1111|C ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 0.2903739633661969 Q00955 0.9484469890594482 0.9504740238189696 0.8994590044021606 0.8926740288734436 0.19778165221214292 0.01358390972018242 0.226977601647377 0.08725195378065109 51.636703964658864 45.0 0.0 no 12383 chrXIV_658081 31530 essential YNR016C 3274 - AGTCACAACTGGGTCTTGAT silent|GTG>GTC|V|1097 silent|GTG>GTA|V|1097 V|1097|L V|1097|M ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -0.6521565778589606 Q00955 0.9539830088615416 0.9587630033493042 0.08109601587057114 0.003007513238117099 48.37898467567043 45.0 0.0 no 12384 chrXIV_658202r 31532 essential YNR016C 3150 + TCTGTTGTGAAGGTTGCCTA S|1051|C S|1051|F ACC1 Acetyl-CoA Carboxylase 2233.0 0 1 0 0 -0.2364224573595444 Q00955 0.945252001285553 0.9294660091400146 0.01659439504146576 0.02640015073120594 51.379076088455065 45.0 0.0 no 12385 chrXIV_658071 31533 essential YNR016C 3284 - CAGCTGCAGCAGTCACAACT A|1101|P A|1101|T A|1100|P A|1100|T ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -0.6920209279991315 Q00955 0.9573720097541808 0.9523990154266356 0.9573720097541808 0.9523990154266356 0.006759141571819782 0.005688452161848545 0.01100969035178423 0.08956919610500336 53.74260941089011 55.00000000000001 0.0 no 12386 chrXIV_658250 31534 essential YNR016C 3105 - TCAGTTCTTTCCTTGACCGA E|1042|Q E|1042|K R|1040|T R|1040|K ACC1 Acetyl-CoA Carboxylase 2233.0 0 1 0 0 -0.8002350724911115 Q00955 0.956179976463318 0.9475290179252625 0.932735025882721 0.955805003643036 0.17190483212471008 0.26731494069099426 0.0 0.0 52.66050033706102 45.0 0.0 no 12387 chrXIV_658478 31537 essential YNR016C 2877 - GCAACTTTATCTAGATCTTT A|966|P A|966|T V|965|L V|965|I ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 0.4324378548274152 Q00955 0.9573720097541808 0.9523990154266356 0.9539830088615416 0.9574310183525084 0.05778270214796066 0.32389768958091736 0.07969466596841812 0.09362412989139557 4.5635337829589835 0.7285000085830688 -0.7883999943733215 -0.5213800072669983 41.60849340576721 30.0 0.0 no 12388 chrXIV_658479 31538 essential YNR016C 2876 - CAACTTTATCTAGATCTTTA V|965|L V|965|I ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 0.5825607821216643 Q00955 0.9539830088615416 0.9574310183525084 0.07969466596841812 0.09362412989139557 -0.7883999943733215 -0.5213800072669983 37.30391122785603 25.0 0.0 no 12389 chrXIV_658593 31539 essential YNR016C 2762 - GGACAAATATAGAATGTTCA V|927|L V|927|I ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 0.6472597267269659 Q00955 0.9539830088615416 0.9574310183525084 0.3380489945411682 0.20522326231002808 -0.3102400004863739 -0.37992000579833984 35.615228949139805 30.0 0.0 no 12390 chrXIV_658624r 31541 essential YNR016C 2728 + TTGCTCATAAGTACTCTAAC A|911|G A|911|V H|912|D H|912|Y ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 0.2437084550911099 Q00955 0.9484469890594482 0.9504740238189696 0.9473130106925964 0.9489949941635132 0.0017807246185839176 1.0 0.3513268828392029 0.010226995684206486 1.6030000448226929 1.187000036239624 0.5153399705886841 -1.0225199460983276 40.52484549009745 35.0 0.0 no 12391 chrXIV_658674r 31546 essential YNR016C 2678 + ATACAACCCCGACAAATTGC Y|894|* silent|TAC>TAT|Y|894 N|895|K silent|AAC>AAT|N|895 ACC1 Acetyl-CoA Carboxylase 2233.0 0 1 0 0 -0.6386351374730704 Q00955 0.9439849853515624 1.0 1.679800033569336 45.74911029405064 45.0 0.0 no 12392 chrXIV_658788r 31547 essential YNR016C 2564 + TGCTAAGCTAGATGAACAAA A|856|G A|856|V ACC1 Acetyl-CoA Carboxylase 2233.0 0 1 0 0 0.3293589626679977 Q00955 0.9484469890594482 0.9504740238189696 0.3839424550533295 0.3239448368549347 0.44179999828338623 0.22105999290943146 37.754764758624724 35.0 0.0 no 12393 chrXIV_659015 31548 essential YNR016C 2340 - TCTGGCAGCATACCTTCAAA D|787|H D|787|N silent|CTG>CTC|L|785 silent|CTG>CTA|L|785 ACC1 Acetyl-CoA Carboxylase 2233.0 0 1 0 0 -0.16126100290778292 Q00955 0.9486550092697144 0.956179976463318 0.11928001046180725 0.4919243156909943 49.384210347995 45.0 0.0 no 12394 chrXIV_659093r 31549 essential YNR016C 2259 + CCTGGTTCTACCATTGTTGC P|754|R P|754|L ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 0.7857658304818824 Q00955 0.9432820081710817 0.9430609941482544 0.01613645814359188 0.02721427753567696 54.95598189917473 50.0 0.0 no 12395 chrXIV_659052r 31551 essential YNR016C 2300 + GACTCTTGACGATCCATCCA T|768|S T|768|I L|769|V L|769|F ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -0.6538623904921586 Q00955 0.9491789937019348 0.9472420215606691 0.9512209892272948 0.9587849974632264 0.5152416825294495 0.10640392452478407 0.005871783476322889 0.00576051464304328 51.90913938734218 50.0 0.0 no 12396 chrXIV_659241r 31554 essential YNR016C 2111 + TACTCCATCCCCTGGTAAAT T|705|S T|705|I P|706|A P|706|S ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 0.05418173375650241 Q00955 0.9491789937019348 0.9472420215606691 0.9562489986419678 0.9498909711837769 1.0 0.003336261259391904 0.038808103650808334 0.1005345582962036 52.235220996641324 45.0 0.0 no 12397 chrXIV_659292r 31555 essential YNR016C 2060 + TGACTCTATGACTACTTTGT D|688|E silent|GAC>GAT|D|688 S|689|C S|689|F ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 0.4206574079946822 Q00955 0.9532920122146606 0.945252001285553 0.9294660091400146 0.04638001695275307 0.023133113980293274 0.014262950047850609 43.093332500258725 35.0 0.0 no 12398 chrXIV_659335 31556 essential YNR016C 2020 - AACTTCTTCTTTCCAATAGA V|680|L V|680|I E|679|Q E|679|K ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -0.3313748814701231 Q00955 0.9539830088615416 0.9574310183525084 0.956179976463318 0.9475290179252625 0.036066774278879166 0.2621358633041382 0.01963881962001324 0.015479368157684803 41.92644783500799 30.0 0.0 no 12399 chrXIV_659393r 31558 essential YNR016C 1959 + ATACTGCGTCAACTATCTGA L|655|V silent|CTG>TTG|L|655 R|656|G R|656|C ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -0.14384019733550588 Q00955 0.9512209892272948 0.8994590044021606 0.8926740288734436 1.0 0.06949660927057266 0.010284468531608582 44.82485103175066 40.0 0.0 no 12400 chrXIV_659455 31559 essential YNR016C 1900 - GTCATTACCGGATTTAGCTA D|640|H D|640|N ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 1.0637549937724209 Q00955 0.9486550092697144 0.956179976463318 0.16520431637763974 0.8732542395591736 47.84446287882969 40.0 0.0 no 12401 chrXIV_659481 31560 essential YNR016C 1874 - ACTTGTATCTTTTACCCTCA K|631|N silent|AAG>AAA|K|631 ACC1 Acetyl-CoA Carboxylase 2233.0 0 1 0 0 1.1709306763087777 Q00955 0.9355990290641784 0.5924324989318848 49.16435318943144 35.0 0.0 no 12402 chrXIV_659624r 31566 essential YNR016C 1728 + CCAACTCTTGCCGTCATTTG P|577|R P|577|L T|578|S T|578|I ACC1 Acetyl-CoA Carboxylase 2233.0 0 1 0 0 0.030218699487927683 Q00955 0.9432820081710817 0.9430609941482544 0.9491789937019348 0.9472420215606691 0.5384655594825745 0.332305520772934 0.01885346509516239 0.4222213625907898 51.908249913854554 50.0 0.0 no 12403 chrXIV_659677 31567 essential YNR016C 1678 - AATCAAATCGTCCAACCAAC L|565|F silent|TTG>TTA|L|565 ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 0.7947679903374079 Q00955 0.9587849974632264 0.043274026364088065 0.3414599895477295 41.309654464032754 40.0 0.0 no 12404 chrXIV_659688r 31568 essential YNR016C 1664 + CACTATTACCACCGGTTGGT T|556|S T|556|I ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -1.4404073610383024 Q00955 0.9491789937019348 0.9472420215606691 0.687133252620697 0.16349242627620694 -0.8904399871826172 -1.0643800497055054 52.85999372947039 50.0 0.0 no 12405 chrXIV_659776 31570 essential YNR016C 1579 - CCTAATGGACAATTCCTTCA R|533|T R|533|K ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -0.8821916722594291 Q00955 0.932735025882721 0.955805003643036 0.02249086461961269 0.06519529223442078 0.6543599963188171 0.5306400060653687 46.027859534034796 40.0 0.0 no 12406 chrXIV_659797 31571 essential YNR016C 1558 - GGCAACAACCATGTGTTTCC A|526|P A|526|T V|525|L V|525|I ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -2.043234746741855 Q00955 0.9573720097541808 0.9523990154266356 0.9539830088615416 0.9574310183525084 0.02573846466839313 0.004796895664185286 0.4823988080024719 0.3033212721347809 5.546060085296631 2.408940076828003 -0.6532800197601318 -0.4891799986362457 51.08896042792219 50.0 0.0 yes 12407 chrXIV_659855r 31573 essential YNR016C 1497 + TCCTTTTCGGACTCTCAGTT silent|TCC>TCG|S|500 silent|TCC>TCT|S|500 S|500|C S|500|F ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -0.18893065435781206 Q00955 0.945252001285553 0.9294660091400146 0.0018321842653676867 0.002072155475616455 0.0551999993622303 2.853140115737915 53.1691945960709 45.0 0.0 no 12408 chrXIV_659888r 31574 essential YNR016C 1464 + TACTTCTCCGTGGGTAACAA Y|489|* silent|TAC>TAT|Y|489 F|490|L silent|TTC>TTT|F|490 ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 0.22101997583606225 Q00955 0.9387490153312684 0.0 0.8342000246047974 47.962068621363755 45.0 0.0 no 12409 chrXIV_659913r 31575 essential YNR016C 1439 + CCGTTCTTCCTCTAATGTTT R|481|G R|481|C S|482|C S|482|F ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -0.1991857774936008 Q00955 0.8994590044021606 0.8926740288734436 0.945252001285553 0.9294660091400146 0.0 0.0 0.0 0.0 1.0413999557495115 0.6504200100898743 0.5044400095939636 0.27974000573158264 50.603693712773065 40.0 0.0 no 12410 chrXIV_659945 31576 essential YNR016C 1410 - TCATGCAAAGTACCACCCGA E|477|Q E|477|K L|475|F silent|TTG>TTA|L|475 ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -0.7865741168668627 Q00955 0.956179976463318 0.9475290179252625 0.9587849974632264 0.008212861604988575 0.006346454843878746 0.006487730424851179 0.5666400194168091 0.7420600056648254 5.640719890594482 50.955885352756646 50.0 0.0 no 12411 chrXIV_660021r 31582 essential YNR016C 1331 + ACAAAGAAGACCTATTCCAA Q|445|E Q|445|* ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 0.2635456811266333 Q00955 0.9590039849281312 1.0 2.572619915008545 39.88158698558095 35.0 0.0 no 12412 chrXIV_660123 31584 essential YNR016C 1232 - TGTCACTTATTCTATGCATA D|417|H D|417|N S|416|T S|416|N ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -0.06107832048432772 Q00955 0.9486550092697144 0.956179976463318 0.9512869715690612 0.9536849856376648 0.04182176664471626 0.011859227903187277 0.05259502679109573 0.04801637679338455 0.975220024585724 0.9811800122261048 -0.41444000601768494 -0.12887999415397644 42.82276718643403 30.0 0.0 no 12413 chrXIV_660150r 31586 essential YNR016C 1202 + AGCTCAATTACAAATCGCTA A|402|G A|402|V Q|403|E Q|403|* ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 0.2836387549288488 Q00955 0.9484469890594482 0.9504740238189696 0.9590039849281312 0.024838369339704517 0.07107149809598923 0.0 2.1635000705718994 -1.1313999891281128 0.5623400211334229 41.28122608809434 35.0 0.0 no 12414 chrXIV_660169 31588 essential YNR016C 1186 - AGCTGCAGGTAAGTTAACAC A|402|P A|402|T A|401|P A|401|T ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -5.965675897563492 Q00955 0.9573720097541808 0.9523990154266356 0.9573720097541808 0.9523990154266356 0.017888391390442848 0.17403529584407804 0.0 0.0 4.580999851226807 -0.07169999927282332 -0.4930399954319 2.694240093231201 45.6375657286253 45.0 0.0 yes 12415 chrXIV_660201r 31589 essential YNR016C 1151 + ACAAGTCGAGCATCCAACAA Q|385|E Q|385|* silent|GTC>GTG|V|386 silent|GTC>GTT|V|386 ACC1 Acetyl-CoA Carboxylase 2233.0 0 1 0 0 -0.0541613410840763 Q00955 0.9590039849281312 0.0 0.5209199786186218 45.294247162137076 45.0 0.0 no 12416 chrXIV_660307 31591 essential YNR016C 1048 - GACTAGTTTCCCCAGTCTGA V|356|L V|356|I ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -1.5563029879820125 Q00955 0.9539830088615416 0.9574310183525084 0.0 0.0 -0.0051600001752376565 -1.1012799739837646 56.25128797058011 50.0 0.0 no 12417 chrXIV_660333r 31592 essential YNR016C 1019 + AACATTTCACGAGATGGAAA T|341|R T|341|I ACC1 Acetyl-CoA Carboxylase 2233.0 1 Series([], Name: modification, dtype: object) 0 0 0 -1.1711163712519777 Q00955 0.9476869702339172 0.9472420215606691 0.06915097683668138 0.4596225321292877 -1.543560028076172 -1.2381600141525269 37.68476076147221 35.0 0.0 no 12418 chrXIV_660356 31595 essential YNR016C 999 - TCAGCCTTGGCAATTGTAAC E|340|Q E|340|K A|339|P A|339|T ACC1 Acetyl-CoA Carboxylase 2233.0 0 1 0 0 -2.526192283433447 Q00955 0.956179976463318 0.9475290179252625 0.9573720097541808 0.9523990154266356 0.18544365465641025 0.2392595708370209 1.0 0.03598013892769813 0.5843600034713745 0.9019600152969359 -0.8393599987030029 0.3935000002384186 48.108763355384504 45.0 0.0 yes 12419 chrXIV_660499 31597 essential YNR016C 856 - CAACTTCATGATGAAAATGG K|291|N silent|AAG>AAA|K|291 M|290|I M|290|I ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -0.3519443980745823 Q00955 0.9355990290641784 0.9553959965705872 0.9553959965705872 0.010379227809607984 0.0 0.0 2.5720999240875244 -0.13544000685214996 -0.13544000685214996 35.07270686008457 35.0 0.0 no 12420 chrXIV_660543r 31598 essential YNR016C 809 + TTTCATCGCTTTATACCACC F|271|L silent|TTC>TTT|F|271 I|272|M silent|ATC>ATT|I|272 ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -0.14371336822113 Q00955 0.9387490153312684 0.9598389863967896 0.11076369136571884 0.0230405367910862 2.4719998836517334 -0.06598000228404999 48.92653374877011 40.0 0.0 no 12421 chrXIV_660628 31600 essential YNR016C 727 - GACAGGAAAACCAATACGCT V|249|L V|249|I ACC1 Acetyl-CoA Carboxylase 2233.0 0 1 0 0 1.0845441966575788 Q00955 0.9539830088615416 0.9574310183525084 0.3679508566856384 0.057003144174814224 3.5957400798797607 0.33625999093055725 42.303269277625866 45.0 0.0 no 12422 chrXIV_660650 31602 essential YNR016C 705 - GCCTTTTGTAAACCATCTTC K|241|N silent|AAG>AAA|K|241 A|242|P A|242|T ACC1 Acetyl-CoA Carboxylase 2233.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.6628910191594967 Q00955 0.9355990290641784 0.9573720097541808 0.9523990154266356 0.21374957263469696 0.005431195721030235 0.0042319875210523605 0.9565799832344056 8.653019905090332 4.729340076446533 47.87091045184866 40.0 0.0 no 12423 chrXIV_660892 31613 essential YNR016C 463 - TTCAGGCAATAGTGGATTCT E|161|Q E|161|K L|159|F silent|TTG>TTA|L|159 ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -1.0434594590252009 Q00955 0.956179976463318 0.9475290179252625 0.9587849974632264 0.009910871274769306 0.0077638402581214905 0.0 0.16459999978542328 -0.21831999719142914 3.894599914550781 46.466515449259994 40.0 0.0 no 12424 chrXIV_660934r 31619 essential YNR016C 418 + GAGCAGACGTAGACGCCGTA A|141|G A|141|V ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 1.4140611557968898 Q00955 0.9484469890594482 0.9504740238189696 0.003876545233651996 1.0 0.7300599813461304 1.4909199476242063 53.49898980337343 60.0 0.0 no 12425 chrXIV_661013r 31621 essential YNR016C 339 + GATCAATACATTGAAGTGCC Q|115|E Q|115|* ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -1.5602650809701504 Q00955 0.9590039849281312 0.04314975440502167 0.4930199980735779 42.47517190459428 40.0 0.0 no 12426 chrXIV_661015 31622 essential YNR016C 340 - TGGCACTTCAATGTATTGAT silent|GTG>GTC|V|119 silent|GTG>GTA|V|119 V|119|L V|119|M ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -0.5212639309523652 Q00955 0.9539830088615416 0.9587630033493042 0.011013575829565523 0.0026422867085784674 1.3289400339126587 1.5094000101089478 43.292753479191504 35.0 0.0 no 12427 chrXIV_661123 31624 essential YNR016C 232 - CTCGTATGCCCATTTTCTGA E|84|Q E|84|K ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -0.3223699040890288 Q00955 0.956179976463318 0.9475290179252625 0.014240304939448832 0.014132896438241003 -0.3138000071048737 -0.6043999791145325 52.55025244093326 45.0 0.0 no 12428 chrXIV_661220 31626 essential YNR016C 135 - CTCTTAACAAAGTCCCTTAA K|51|N silent|AAG>AAA|K|51 ACC1 Acetyl-CoA Carboxylase 2233.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.77164358034991 Q00955 0.9355990290641784 0.5125815868377686 1.0674200057983398 42.15925499436969 35.0 0.0 no 12429 chrXIV_661274r 31630 essential YNR016C 78 + GAACTTCCAGGTCATTTCAT L|28|V L|28|F P|29|A P|29|S ACC1 Acetyl-CoA Carboxylase 2233.0 0 0 0 0 -0.15900930290651832 Q00955 0.9512209892272948 0.9587849974632264 0.9562489986419678 0.9498909711837769 1.0 0.12107080221176147 1.0 0.8901189565658569 3.3198399543762207 8.301340103149414 1.878000020980835 2.4382998943328857 47.774349033671 40.0 0.0 no 12430 chrXIV_662972 31633 essential YNR017W 59 + CCAAGATACAACCAAGCCTA Q|21|E Q|21|* TIM23 Translocase of the Inner Mitochondrial membrane 222.0 0 0 0 0 0.8485165788032912 P32897 0.9590039849281312 1.0 46.494948705065156 45.0 1.0 no 12431 chrXIV_662983r 31635 essential YNR017W 73 - CAACGATAGTTCCTTAGGCT silent|TCG>TCC|S|30 silent|TCG>TCA|S|30 TIM23 Translocase of the Inner Mitochondrial membrane 222.0 0 0 0 0 0.5077619052021031 P32897 48.421039740454894 45.0 1.0 no 12432 chrXIV_662988r 31636 essential YNR017W 78 - TGCTTCAACGATAGTTCCTT K|32|N silent|AAG>AAA|K|32 L|31|F silent|TTG>TTA|L|31 TIM23 Translocase of the Inner Mitochondrial membrane 222.0 0 0 0 0 -0.3071258449051095 P32897 0.9355990290641784 0.9587849974632264 0.5234536528587341 0.8432464003562927 47.79367754676378 40.0 1.0 no 12433 chrXIV_663039 31637 essential YNR017W 126 + AACATAATATCAGGTCCTGG N|43|K silent|AAC>AAT|N|43 TIM23 Translocase of the Inner Mitochondrial membrane 222.0 0 0 0 0 -0.7162241564328868 P32897 0.9439849853515624 0.7683126330375671 43.16578485214478 40.0 1.0 no 12434 chrXIV_663138 31641 essential YNR017W 225 + GAACAACTATCCTCGTTAGA Q|77|E Q|77|* L|78|V silent|CTA>TTA|L|78 TIM23 Translocase of the Inner Mitochondrial membrane 222.0 0 0 0 0 0.21198824104668354 P32897 0.9590039849281312 0.9512209892272948 1.0 0.2258104383945465 43.274154844483796 40.0 1.0 no 12435 chrXIV_663147 31642 essential YNR017W 234 + TCCTCGTTAGAAGGCTCACA silent|TCC>TCG|S|79 silent|TCC>TCT|S|79 S|79|C S|79|F TIM23 Translocase of the Inner Mitochondrial membrane 222.0 0 0 0 0 -0.35874768038410604 P32897 0.945252001285553 0.9294660091400146 0.012565100565552713 0.0075454767793416986 52.15058132261549 50.0 1.0 no 12436 chrXIV_663177r 31645 essential YNR017W 267 - TCATCGGTCCACCCACGGGA D|96|H D|96|N D|95|H D|95|N TIM23 Translocase of the Inner Mitochondrial membrane 222.0 0 0 0 0 -0.08405315950986869 P32897 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.0027419328689575195 0.008244698867201805 0.0 0.0 60.66666774546274 65.0 1.0 no 12437 chrXIV_663220r 31649 essential YNR017W 310 - ACCAAGTCCCAGCAGGTAGA G|110|R G|110|S G|110|A G|110|D TIM23 Translocase of the Inner Mitochondrial membrane 222.0 0 0 0 0 -1.9529880865563871 P32897 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.06255777180194855 0.5232642292976379 1.0 0.07295453548431396 56.7356530252448 55.00000000000001 1.0 no 12438 chrXIV_663288r 31652 essential YNR017W 378 - TGCAATTTTCCGGGACTATT L|132|F silent|TTG>TTA|L|132 TIM23 Translocase of the Inner Mitochondrial membrane 222.0 0 0 0 0 0.3411085273004939 P32897 0.9587849974632264 0.01467778440564871 47.33363793529651 40.0 1.0 no 12439 chrXIV_663289r 31653 essential YNR017W 379 - TTGCAATTTTCCGGGACTAT L|132|F silent|TTG>TTA|L|132 TIM23 Translocase of the Inner Mitochondrial membrane 222.0 0 0 0 0 0.5754536103735547 P32897 0.9587849974632264 0.01467778440564871 47.33363793529651 40.0 1.0 no 12440 chrXIV_663323r 31654 essential YNR017W 413 - CTCTCTTAGTAATGTGATTC R|144|T R|144|K K|143|N silent|AAG>AAA|K|143 TIM23 Translocase of the Inner Mitochondrial membrane 222.0 0 1 0 0 -0.42874312914443424 P32897 0.932735025882721 0.955805003643036 0.9355990290641784 0.06848109513521193 0.0390838049352169 0.014401056803762913 41.574197837277715 35.0 1.0 no 12441 chrXIV_663336 31655 essential YNR017W 423 + ACTAAGAGAGGTCCCTTCTT T|142|S T|142|I TIM23 Translocase of the Inner Mitochondrial membrane 222.0 0 1 0 0 -0.8744507990275422 P32897 0.9491789937019348 0.9472420215606691 0.04292766004800797 0.004148541484028101 51.02159578985828 45.0 1.0 no 12442 chrXIV_663348r 31656 essential YNR017W 438 - CCCGCATTATTACCTAAGAA silent|GCG>GCC|A|152 silent|GCG>GCA|A|152 G|153|R G|153|R TIM23 Translocase of the Inner Mitochondrial membrane 222.0 0 0 0 0 -0.944355082717274 P32897 0.941340982913971 0.941340982913971 0.0 0.0 46.11183919069896 40.0 1.0 no 12443 chrXIV_663349 31657 essential YNR017W 436 + CCTTCTTAGGTAATAATGCG silent|CCC>CCG|P|146 silent|CCC>CCT|P|146 F|147|L silent|TTC>TTT|F|147 TIM23 Translocase of the Inner Mitochondrial membrane 222.0 0 0 0 1 -0.4203224964409295 P32897 0.9387490153312684 0.010885092429816723 43.41694080225278 40.0 1.0 no 12444 chrXIV_663402 31658 essential YNR017W 489 + TCTACAATAGATGCACTAAG S|164|C S|164|F T|165|R T|165|I TIM23 Translocase of the Inner Mitochondrial membrane 222.0 0 0 0 0 -0.2997957589464059 P32897 0.945252001285553 0.9294660091400146 0.9476869702339172 0.9472420215606691 0.10664148628711699 0.011772693134844305 0.34782013297080994 0.3865280449390411 37.75206726298831 35.0 1.0 no 12445 chrXIV_673705r 31659 essential YNR026C 962 + TACATATGTGGCGAGTGTTT T|322|R T|322|I SEC12 SECretory 471.0 0 0 0 0 0.6517288779314561 P11655 0.9528260231018066 0.9646379947662354 0.7113320231437683 0.023079980164766308 0.19208000600337985 0.11687999963760375 46.55560118796478 40.0 0.0 no 12446 chrXIV_673717r 31661 essential YNR026C 950 + CTCTCCGGACTCTACATATG S|318|C S|318|F P|319|A P|319|S SEC12 SECretory 471.0 0 0 0 0 -0.29732599600096704 P11655 0.9879119992256165 0.9685909748077391 0.924588978290558 0.9161090254783629 0.002063901862129569 0.0010364196496084332 0.031613241881132126 0.0676732137799263 2.3004000186920166 34.24095916748047 2.3639400005340576 3.1781799793243413 49.18852843052979 50.0 0.0 no 12447 chrXIV_673732r 31662 essential YNR026C 935 + TACAGAGGTCACTATCTCTC T|313|R T|313|I SEC12 SECretory 471.0 0 0 0 0 -1.8419914681939584 P11655 0.9773380160331726 0.9893620014190674 0.0 0.0 0.20382000505924225 0.33550000190734863 47.61389587434735 45.0 0.0 no 12448 chrXIV_673747r 31663 essential YNR026C 920 + TCATAGTTTTGCCATTACAG H|308|D H|308|Y SEC12 SECretory 471.0 0 0 0 0 0.431349048192271 P11655 0.9914770126342772 0.9916279911994934 0.0 0.0 2.7454800605773926 8.17646598815918 44.66693594707107 35.0 0.0 no 12449 chrXIV_673857r 31666 essential YNR026C 810 + TCTATGGATGTCGACATGAA S|271|C S|271|F SEC12 SECretory 471.0 0 0 0 0 -0.33492623396396914 P11655 0.9720100164413452 0.9521960020065308 0.009472412057220936 0.0037383425515145055 0.8505200147628784 10.728143692016602 42.5056795671577 40.0 0.0 no 12450 chrXIV_673858r 31667 essential YNR026C 809 + TTCTATGGATGTCGACATGA S|271|C S|271|F SEC12 SECretory 471.0 0 0 0 0 0.1664461465808027 P11655 0.9720100164413452 0.9521960020065308 0.009472412057220936 0.0037383425515145055 0.8505200147628784 10.728143692016602 44.23239603904807 40.0 0.0 no 12451 chrXIV_673991 31669 essential YNR026C 679 - TGCTATCAATACTGTGTCAT A|233|P A|233|T L|231|F silent|TTG>TTA|L|231 SEC12 SECretory 471.0 0 0 0 0 0.4947660179731703 P11655 0.9846779704093932 0.97638601064682 0.989130973815918 0.02494790218770504 0.04346558824181557 0.015253713354468347 3.1665399074554443 1.9337600469589236 6.985249996185303 3.363539934158325 1.2722400426864624 43.92013815407034 35.0 0.0 no 12452 chrXIV_674131r 31671 essential YNR026C 536 + ACACTTTTCCACTGATGGTA H|180|Q silent|CAC>CAT|H|180 H|180|D H|180|Y SEC12 SECretory 471.0 0 0 0 0 -0.13424638074153766 P11655 0.9860429763793944 0.9745690226554872 0.9747200012207032 0.0593184232711792 0.24897031486034396 0.063099205493927 -2.309400081634521 -1.371899962425232 1.850219964981079 48.07492178420091 40.0 0.0 no 12453 chrXIV_674187 31672 essential YNR026C 483 - AACTTCTCTGTCAAGTCGCT K|167|N silent|AAG>AAA|K|167 E|166|D silent|GAG>GAA|E|166 SEC12 SECretory 471.0 0 0 0 0 -0.6994273130842068 P11655 0.9648680090904236 0.9535670280456544 0.1922929286956787 0.035624273121356964 2.3141000270843506 0.3915799856185913 49.59932194080631 45.0 0.0 no 12454 chrXIV_674188 31673 essential YNR026C 482 - ACTTCTCTGTCAAGTCGCTC K|167|N silent|AAG>AAA|K|167 E|166|D silent|GAG>GAA|E|166 SEC12 SECretory 471.0 0 0 0 0 -0.4783460735690647 P11655 0.9648680090904236 0.9535670280456544 0.1922929286956787 0.035624273121356964 2.3141000270843506 0.3915799856185913 52.58803170822029 50.0 0.0 no 12455 chrXIV_674093 31674 essential YNR026C 577 - AATCACTTCCAAGCTAGAAC silent|GTG>GTC|V|198 silent|GTG>GTA|V|198 V|198|L V|198|M SEC12 SECretory 471.0 0 0 0 0 0.6452529424343132 P11655 0.9786369800567628 0.9877660274505616 0.020514167845249176 0.003902087919414043 0.9233999848365784 0.9103599786758424 42.38580088711541 40.0 0.0 no 12456 chrXIV_674211 31675 essential YNR026C 459 - TCAATGATTCTCATTATAGC D|160|H D|160|N SEC12 SECretory 471.0 0 0 0 0 0.5311896879045108 P11655 0.974511981010437 0.9857460260391236 0.010516825132071972 0.42681652307510376 0.6079199910163879 -0.2785800099372864 39.219420867849976 30.0 0.0 no 12457 chrXIV_674317 31677 essential YNR026C 353 - CGTCAAAGTCTACACTAGTG D|124|H D|124|N SEC12 SECretory 471.0 0 0 0 0 0.2962610986129574 P11655 0.9728149771690368 0.9840490221977234 0.019747443497180942 0.384842574596405 -0.2522599995136261 -0.3335199952125549 43.10674846341101 45.0 0.0 no 12458 chrXIV_674394r 31678 essential YNR026C 273 + ACTAAGATTACCCAAGGTAA T|92|S T|92|I SEC12 SECretory 471.0 0 0 0 0 0.9651627633128266 P11655 0.9665899872779846 0.9646379947662354 0.3438918888568878 0.08561542630195618 -0.0573199987411499 -0.5402799844741821 41.43331552650835 35.0 0.0 no 12459 chrXIV_674384 31679 essential YNR026C 286 - GTGCTTATTACCTTTACCTT K|101|N silent|AAG>AAA|K|101 SEC12 SECretory 471.0 0 0 0 0 0.7749186182396024 P11655 0.9648680090904236 0.2626802325248718 0.4908199906349182 49.18097757722802 35.0 0.0 no 12460 chrXIV_674448r 31682 essential YNR026C 219 + ACTGCAATTGACGCTTCCAA T|74|S T|74|I A|75|G A|75|V SEC12 SECretory 471.0 0 0 0 0 0.0014784538552653215 P11655 0.974179983139038 0.9722279906272888 0.9617729783058168 0.9610000252723694 0.1050236150622368 0.04835835844278336 0.012884468771517277 0.01523908693343401 0.42838001251220703 0.3191800117492676 0.5809199810028076 1.0929800271987915 0.7206400036811829 0.8031600117683411 48.126577823359874 45.0 0.0 no 12461 chrXIV_674449r 31683 essential YNR026C 218 + TACTGCAATTGACGCTTCCA T|74|S T|74|I A|75|G A|75|V SEC12 SECretory 471.0 0 0 0 0 -0.2973923345598338 P11655 0.974179983139038 0.9722279906272888 0.9617729783058168 0.9610000252723694 0.1050236150622368 0.04835835844278336 0.012884468771517277 0.01523908693343401 0.42838001251220703 0.3191800117492676 0.5809199810028076 1.0929800271987915 0.7206400036811829 0.8031600117683411 49.133552554811395 45.0 0.0 no 12462 chrXIV_674523 31684 essential YNR026C 147 - TCCTTCTCAGTATCTTTGGT K|55|N silent|AAG>AAA|K|55 E|56|Q E|56|K SEC12 SECretory 471.0 0 0 0 0 0.036417593940640015 P11655 0.95727801322937 0.9857460260391236 0.9736970067024232 0.017959505319595337 0.056716762483119965 1.0 0.5851200222969055 0.05772000178694725 -0.3914400041103363 52.36632240513711 40.0 0.0 no 12463 chrXIV_674524r 31685 essential YNR026C 143 + TCCTACCAAAGATACTGAGA P|49|R P|49|L P|49|A P|49|S SEC12 SECretory 471.0 0 0 0 0 0.2200797196180222 P11655 0.9589099884033204 0.9670220017433168 0.9839829802513124 0.9755030274391174 0.02970723994076252 0.4503941833972931 0.10804370045661926 0.1290493756532669 15.299870491027832 3.2333800792694087 2.6005799770355225 3.87962007522583 43.39534416754071 40.0 0.0 no 12464 chrXIV_674598r 31688 essential YNR026C 69 + ACATTACTTGTGGCAGGCGG T|24|R T|24|I L|26|V L|26|F SEC12 SECretory 471.0 0 0 0 0 -0.3729226471520721 P11655 0.960204005241394 0.9722279906272888 0.9796620011329652 0.989130973815918 0.11498845368623735 0.6868777871131897 0.17602980136871338 0.012094852514564993 -0.2813799977302551 -0.7706999778747559 3.720580101013184 0.4573000073432922 52.801966618388576 55.00000000000001 0.0 no 12465 chrXIV_674657r 31692 essential YNR026C 10 + TGACAGCTAGTTATAACGTC T|5|R T|5|I A|6|G A|6|V SEC12 SECretory 471.0 0 0 0 0 -1.9309320814589208 P11655 0.9528260231018066 0.9646379947662354 0.9764879941940308 0.9757149815559388 0.044104941189289086 0.016103308647871014 0.14426596462726593 0.11604049801826476 0.5841000080108643 -0.2814399898052216 0.7069000005722046 1.6886600255966189 0.8240000009536743 1.5861599445343018 42.530960465124174 40.0 0.0 no 12466 chrXIV_693296 31693 essential YNR035C 732 - CTACTTTGCTCTGCAACTTT S|250|T S|250|N ARC35 ARp2/3 Complex subunit 342.0 0 1 0 0 0.5098328991760469 P53731 0.3893044292926788 0.2271217554807663 47.84457379757652 40.0 0.0 no 12467 chrXIV_693329 31694 essential YNR035C 699 - AGTCTCTTCAACTCCAATGG R|239|T R|239|K K|238|N silent|AAG>AAA|K|238 ARC35 ARp2/3 Complex subunit 342.0 0 0 0 0 -0.5259192553447873 P53731 0.5333743691444397 0.920298397541046 0.055068347603082664 47.8072367689868 45.0 0.0 no 12468 chrXIV_693342r 31695 essential YNR035C 683 + ATACTCACATGAACCACCAT Y|229|* silent|TAC>TAT|Y|229 S|230|* S|230|L ARC35 ARp2/3 Complex subunit 342.0 0 0 0 0 -2.801294148916956 P53731 0.021338561549782756 45.792098634837025 40.0 0.0 yes 12469 chrXIV_693544 31698 essential YNR035C 484 - GAACAAAGTGTTGTCTCCAT L|167|F silent|TTG>TTA|L|167 ARC35 ARp2/3 Complex subunit 342.0 0 0 0 0 0.14873253127540226 P53731 0.03869134932756424 -0.09399999678134917 44.44787206041815 40.0 0.0 no 12470 chrXIV_693581r 31701 essential YNR035C 444 + CCTGTCGAAGCAGAAATTAC P|149|R P|149|L silent|GTC>GTG|V|150 silent|GTC>GTT|V|150 ARC35 ARp2/3 Complex subunit 342.0 0 0 0 0 -1.1801117102690866 P53731 0.8423287272453308 0.7054044008255005 42.839238778792954 45.0 0.0 no 12471 chrXIV_693697 31705 essential YNR035C 331 - AATCGATTCTTGAACCAATT silent|TCG>TCC|S|116 silent|TCG>TCA|S|116 ARC35 ARp2/3 Complex subunit 342.0 0 0 0 0 0.8823621808750598 P53731 39.01197371934967 30.0 0.0 no 12472 chrXIV_693720r 31706 essential YNR035C 305 + CTACACTCTTCAGATTACGT Y|103|* silent|TAC>TAT|Y|103 T|104|S T|104|I ARC35 ARp2/3 Complex subunit 342.0 0 0 0 0 -0.5455390835193811 P53731 1.0 0.006098202895373106 45.065467675812776 40.0 0.0 no 12473 chrXIV_693746 31707 essential YNR035C 282 - TAGCCGGGCTCCACTTCACT G|100|A G|100|D G|100|R G|100|S ARC35 ARp2/3 Complex subunit 342.0 0 0 0 0 0.8177460100446117 P53731 0.07200976461172104 0.2767592072486877 0.033877760171890266 0.32110363245010376 60.76305712624162 60.0 0.0 no 12474 chrXIV_693777r 31708 essential YNR035C 248 + CCACTACTCCTCTTTGGGTG H|84|Q silent|CAC>CAT|H|84 H|84|D H|84|Y ARC35 ARp2/3 Complex subunit 342.0 0 0 0 0 -0.21900757696390027 P53731 0.5905200839042664 0.6206496953964233 0.05487283691763878 -0.21060000360012052 1.104200005531311 0.42019999027252203 55.94037818174877 55.00000000000001 0.0 no 12475 chrXIV_693778r 31709 essential YNR035C 247 + ACCACTACTCCTCTTTGGGT H|84|D H|84|Y D|83|E silent|GAC>GAT|D|83 ARC35 ARp2/3 Complex subunit 342.0 0 0 0 0 0.14132997819774076 P53731 0.6206496953964233 0.05487283691763878 0.7868753671646118 1.104200005531311 0.42019999027252203 56.51271728325895 50.0 0.0 no 12476 chrXIV_693782r 31710 essential YNR035C 243 + GCCGACCACTACTCCTCTTT silent|GCC>GCG|A|82 silent|GCC>GCT|A|82 A|82|G A|82|V ARC35 ARp2/3 Complex subunit 342.0 0 0 0 0 0.22511074683246746 P53731 0.2586483359336853 0.3665742576122284 1.333199977874756 4.227000236511231 58.27562555444814 55.00000000000001 0.0 no 12477 chrXIV_693900 31711 essential YNR035C 128 - CTTCTGCTGTGTTTGAAATG E|49|Q E|49|K A|48|P A|48|T ARC35 ARp2/3 Complex subunit 342.0 0 0 0 0 -3.6956271387898414 P53731 0.3015456199645996 0.06563779711723328 1.0 0.02387031354010105 5.314000129699707 0.025399999693036083 43.264972065027386 40.0 0.0 yes 12478 chrXIV_693819 31713 essential YNR035C 209 - ACGTCAAAGAACCGTCCAAT silent|ACG>ACC|T|76 silent|ACG>ACA|T|76 L|75|F silent|TTG>TTA|L|75 ARC35 ARp2/3 Complex subunit 342.0 0 0 0 0 0.5471171705219858 P53731 0.06259377300739287 0.4959999918937683 45.021469480099775 45.0 0.0 no 12479 chrXIV_695657 31720 essential YNR038W 62 + AATCGTCGGAACTACTCCCC I|22|M silent|ATC>ATT|I|22 silent|GTC>GTG|V|23 silent|GTC>GTT|V|23 DBP6 Dead Box Protein 629.0 0 1 0 0 -0.8517584941028334 P53734 0.2906698286533356 52.44114242267994 55.00000000000001 1.0 no 12480 chrXIV_695758r 31724 essential YNR038W 166 - GTCTTCCTCTGAACTAGAGT D|62|H D|62|N E|61|Q E|61|K DBP6 Dead Box Protein 629.0 0 0 0 0 0.8384489182071546 P53734 0.05413491651415825 0.14692936837673187 0.13279393315315247 0.13930656015872955 49.959974744263256 45.0 1.0 no 12481 chrXIV_695853r 31727 essential YNR038W 261 - AGCACTGTGCTGTGAGTACT silent|GTG>GTC|V|93 silent|GTG>GTA|V|93 V|93|L V|93|M DBP6 Dead Box Protein 629.0 0 0 0 0 -1.3143546122751617 P53734 0.08472593873739243 0.01595619507133961 53.28498535811343 50.0 1.0 no 12482 chrXIV_695921 31729 essential YNR038W 326 + ATCTGATATTGCTGAGAGTA S|110|C S|110|F DBP6 Dead Box Protein 629.0 0 0 0 0 -0.4176949189043525 P53734 0.021574120968580246 0.02292684465646744 42.79076194334408 35.0 1.0 no 12483 chrXIV_696041 31731 essential YNR038W 446 + TTCATTACAGTTCAAATCTA S|150|* S|150|L DBP6 Dead Box Protein 629.0 0 0 0 0 0.2036861154474792 P53734 0.32713061571121216 37.42109915985196 25.0 1.0 no 12484 chrXIV_696046 31732 essential YNR038W 451 + TACAGTTCAAATCTACGGGT Q|152|E Q|152|* DBP6 Dead Box Protein 629.0 0 0 0 0 -0.08602880405513524 P53734 0.4610274434089661 43.78276501344925 40.0 1.0 no 12485 chrXIV_696111r 31733 essential YNR038W 519 - TCATTTGCGTAATCCGAGAA E|180|Q E|180|K DBP6 Dead Box Protein 629.0 0 0 0 0 0.6340468789242695 P53734 0.5540071725845337 0.8513248562812805 44.394035917159776 40.0 1.0 no 12486 chrXIV_696203 31735 essential YNR038W 608 + CATCCTAGACTCCATATTAC I|204|M silent|ATC>ATT|I|204 L|205|V silent|CTA>TTA|L|205 DBP6 Dead Box Protein 629.0 0 0 0 0 0.2947097290591453 P53734 0.0799260064959526 0.10471727699041368 45.91165499809824 40.0 1.0 no 12487 chrXIV_696206r 31736 essential YNR038W 614 - ATACCGGTAATATGGAGTCT V|211|L V|211|I silent|CCG>CCC|P|210 silent|CCG>CCA|P|210 DBP6 Dead Box Protein 629.0 0 0 0 0 -0.2960494717495297 P53734 0.32384514808654785 0.2132534235715866 45.45176987999047 40.0 1.0 no 12488 chrXIV_696282 31737 essential YNR038W 687 + ATTCTTGTAAATGCTGCTAC L|231|V L|231|F DBP6 Dead Box Protein 629.0 0 0 0 0 0.4311041931786115 P53734 0.0 0.0 42.25925558703784 35.0 1.0 no 12489 chrXIV_696426 31738 essential YNR038W 831 + ACGTTGACAAAGCTAACTCA T|278|R T|278|M DBP6 Dead Box Protein 629.0 0 0 0 0 -0.020168030999151317 P53734 0.13349460065364838 0.04115395247936249 41.812274680479725 40.0 1.0 no 12490 chrXIV_696596r 31739 essential YNR038W 1004 - CATCGATAATCAAAAACTTT D|341|H D|341|N DBP6 Dead Box Protein 629.0 0 0 0 0 -0.816460928624741 P53734 0.0 0.0 32.56576539800176 25.0 1.0 no 12491 chrXIV_696705r 31742 essential YNR038W 1113 - ATCATTTTGATCACGTTCCC M|377|I M|377|I DBP6 Dead Box Protein 629.0 0 0 0 0 -0.4075035246747477 P53734 0.3315159380435944 0.3315159380435944 48.90415945960609 40.0 1.0 no 12492 chrXIV_696748r 31743 essential YNR038W 1156 - GCCGTTTAACTTTTCTGTGT G|392|R G|392|S G|392|A G|392|D DBP6 Dead Box Protein 629.0 0 0 0 0 0.2635400334376178 P53734 0.14140473306179047 0.5079252719879149 0.1983331143856049 0.8121732473373413 49.926985071711556 40.0 1.0 no 12493 chrXIV_696929r 31744 essential YNR038W 1337 - TCAAAATCTTTGCAGCAATG L|452|F silent|TTG>TTA|L|452 DBP6 Dead Box Protein 629.0 0 0 0 0 0.5267691615958595 P53734 0.0 39.069524149184595 35.0 1.0 no 12494 chrXIV_696931r 31746 essential YNR038W 1339 - AATCAAAATCTTTGCAGCAA L|452|F silent|TTG>TTA|L|452 DBP6 Dead Box Protein 629.0 0 0 0 0 -0.2265751758032491 P53734 0.0 37.768679103941615 30.0 1.0 no 12495 chrXIV_701933 31747 essential YNR043W 38 + CATCGCAACCCTTAAGTATT I|14|M silent|ATC>ATT|I|14 A|15|G A|15|V MVD1 MeValonate pyrophosphate Decarboxylase 396.0 0 0 0 0 0.7747470431323515 P32377 0.9598389863967896 0.9484469890594482 0.9504740238189696 0.0 0.0 0.0 -0.1518000066280365 1.0985000133514404 0.8492799997329712 1.2832599878311155 4.172200202941895 46.47446726187923 40.0 1.0 no 12496 chrXIV_701934 31748 essential YNR043W 39 + ATCGCAACCCTTAAGTATTG I|14|M silent|ATC>ATT|I|14 A|15|G A|15|V MVD1 MeValonate pyrophosphate Decarboxylase 396.0 0 0 0 0 0.06948214385049739 P32377 0.9598389863967896 0.9484469890594482 0.9504740238189696 0.0 0.0 0.0 -0.1518000066280365 1.0985000133514404 0.8492799997329712 1.2832599878311155 4.172200202941895 45.254320388080366 40.0 1.0 no 12497 chrXIV_701932 31750 essential YNR043W 37 + ACATCGCAACCCTTAAGTAT N|13|K silent|AAC>AAT|N|13 I|14|M silent|ATC>ATT|I|14 MVD1 MeValonate pyrophosphate Decarboxylase 396.0 0 0 0 0 -0.4886958913488912 P32377 0.9439849853515624 0.9598389863967896 0.0 0.0 2.6363201141357417 -0.1518000066280365 46.64979460146748 40.0 1.0 no 12498 chrXIV_701941r 31752 essential YNR043W 49 - CCTTTTCCCCCAATACTTAA R|23|T R|23|K silent|GGG>GGC|G|21 silent|GGG>GGA|G|21 MVD1 MeValonate pyrophosphate Decarboxylase 396.0 0 1 0 0 0.006650537837801396 P32377 0.932735025882721 0.955805003643036 0.0 0.0 3.0552000999450684 1.6207599639892578 51.04171652629765 40.0 1.0 no 12499 chrXIV_701942r 31753 essential YNR043W 50 - CCCTTTTCCCCCAATACTTA R|23|T R|23|K R|23|S silent|AGG>AGA|R|23 MVD1 MeValonate pyrophosphate Decarboxylase 396.0 0 1 0 0 -0.8334732840984084 P32377 0.932735025882721 0.955805003643036 0.9087679982185364 0.0 0.0 0.0 3.0552000999450684 1.6207599639892578 3.048959970474243 55.99297212489735 45.0 1.0 no 12500 chrXIV_702023 31756 essential YNR043W 128 + CCTCAGAACGTTGACCTCTG silent|CTC>CTG|L|44 silent|CTC>CTT|L|44 L|44|V L|44|F MVD1 MeValonate pyrophosphate Decarboxylase 396.0 0 0 0 0 -0.02848953816964548 P32377 0.9512209892272948 0.9587849974632264 0.010395876131951807 0.010133640840649605 0.947920024394989 1.3612799644470217 0.9550200104713441 1.1084799766540527 51.23784480936479 55.00000000000001 1.0 no 12501 chrXIV_701995r 31757 essential YNR043W 103 - TTGCGATAAAGTCACTGATA silent|TCG>TCC|S|40 silent|TCG>TCA|S|40 MVD1 MeValonate pyrophosphate Decarboxylase 396.0 0 0 0 0 0.6302691910493192 P32377 39.9709543100609 35.0 1.0 no 12502 chrXIV_702066 31759 essential YNR043W 171 + CGCGACACTTTGTGGTTAAA silent|CGC>CGG|R|58 silent|CGC>CGT|R|58 D|59|E silent|GAC>GAT|D|59 MVD1 MeValonate pyrophosphate Decarboxylase 396.0 0 0 0 0 0.4652565390539822 P32377 0.9532920122146606 0.007760282605886459 2.1014599800109863 45.1444106745546 45.0 1.0 no 12503 chrXIV_702134 31760 essential YNR043W 239 + CGACCTACGCCAATTAAGAA D|81|E silent|GAC>GAT|D|81 L|82|V silent|CTA>TTA|L|82 MVD1 MeValonate pyrophosphate Decarboxylase 396.0 0 0 0 0 0.2968686450950329 P32377 0.9532920122146606 0.9512209892272948 1.0 0.3144015371799469 -0.24541999399662015 2.3485798835754395 44.18576185562454 45.0 1.0 no 12504 chrXIV_702143r 31761 essential YNR043W 251 - ATTCCATTTCCTTTCTTAAT E|90|Q E|90|K M|89|I M|89|I MVD1 MeValonate pyrophosphate Decarboxylase 396.0 0 0 0 0 -0.2650027823177866 P32377 0.956179976463318 0.9475290179252625 0.9553959965705872 0.9553959965705872 0.4705504775047302 0.5776962637901306 0.396232545375824 0.396232545375824 -0.4674000144004822 -0.10877999663352966 0.04707999899983406 0.04707999899983406 0.12471999973058699 0.12471999973058699 44.28845587332466 25.0 1.0 no 12505 chrXIV_702217r 31762 essential YNR043W 325 - TGCTGTAGGAAAGTTATTTT A|115|P A|115|T MVD1 MeValonate pyrophosphate Decarboxylase 396.0 0 0 0 0 -3.90223756436575 P32377 0.9573720097541808 0.9523990154266356 0.0 0.0 -0.9349600076675416 0.9389399886131288 -1.792580008506775 0.3940399885177612 40.23159647755261 30.0 1.0 yes 12506 chrXIV_702257 31764 essential YNR043W 362 + CGCTGCTGGCTTTGCTGCAT A|122|G A|122|V A|123|G A|123|V MVD1 MeValonate pyrophosphate Decarboxylase 396.0 0 0 0 0 0.05569037323133978 P32377 0.9484469890594482 0.9504740238189696 0.9484469890594482 0.9504740238189696 0.0 0.0 0.025533463805913925 0.007917976938188076 0.9558799862861632 1.684620022773743 1.6483999490737915 -0.14135999977588656 0.9023200273513794 1.967159986495972 1.7687000036239624 1.4076999425888062 60.11509843978382 60.0 1.0 no 12507 chrXIV_702391r 31768 essential YNR043W 499 - TTCAGCTTTTCCCATTTCCC E|173|Q E|173|K A|172|P A|172|T MVD1 MeValonate pyrophosphate Decarboxylase 396.0 0 0 0 0 0.7216364914857425 P32377 0.956179976463318 0.9475290179252625 0.9573720097541808 0.9523990154266356 0.5843794941902161 0.9154319167137146 0.15215711295604706 0.26880839467048645 -0.3034799993038177 -0.3819000124931336 1.006420016288757 0.5340200066566467 0.5564799904823303 1.2650599479675293 57.45509919249753 45.0 1.0 no 12508 chrXIV_702547r 31770 essential YNR043W 655 - TCTTTCTTTAAATAGTTCGG R|225|T R|225|K E|224|Q E|224|K MVD1 MeValonate pyrophosphate Decarboxylase 396.0 0 0 0 0 -0.04407679989351716 P32377 0.932735025882721 0.955805003643036 0.956179976463318 0.9475290179252625 0.0 0.0 0.4198575019836426 0.2961289584636688 2.649019956588745 1.7228000164031982 0.4692800045013428 0.14010000228881836 3.207200050354004 2.3046000003814697 -1.8242000341415403 -2.3582000732421875 39.123624926699854 30.0 1.0 no 12509 chrXIV_702637r 31773 essential YNR043W 745 - CATCATTGTTTCCTTTGCAA M|254|I M|254|I MVD1 MeValonate pyrophosphate Decarboxylase 396.0 0 0 0 0 0.6064022608240317 P32377 0.9553959965705872 0.9553959965705872 0.0 0.0 1.3071600198745728 1.3071600198745728 1.2869000434875488 1.2869000434875488 46.75178049539505 35.0 1.0 no 12510 chrXIV_702668 31774 essential YNR043W 773 + CTCTTTCCATGCCACATGTT S|259|C S|259|F F|260|L silent|TTC>TTT|F|260 MVD1 MeValonate pyrophosphate Decarboxylase 396.0 0 0 0 0 -0.006259975053515029 P32377 0.945252001285553 0.9294660091400146 0.9387490153312684 0.02765306830406189 0.019871797412633896 0.012301795184612274 -0.7446600198745728 -2.6315200328826904 0.8623800277709961 -0.27959999442100525 1.2294000387191772 53.98895230610743 45.0 1.0 no 12511 chrXIV_702724 31777 essential YNR043W 829 + CTTCCAAGCGTATCATCAGT S|278|C S|278|F silent|TCC>TCG|S|278 silent|TCC>TCT|S|278 MVD1 MeValonate pyrophosphate Decarboxylase 396.0 0 0 0 0 -0.7199600627492379 P32377 0.945252001285553 0.9294660091400146 0.0 0.0 4.355780124664307 30.88245964050293 50.10558755249855 45.0 1.0 no 12512 chrXIV_702754r 31779 essential YNR043W 862 - TTCTCCGTAAAACTGATTAA E|294|Q E|294|K G|293|A G|293|E MVD1 MeValonate pyrophosphate Decarboxylase 396.0 0 0 0 0 0.187394971016882 P32377 0.956179976463318 0.9475290179252625 0.9499930143356324 0.9438679814338684 0.5598825812339783 0.9452497363090516 0.009719007648527622 0.010904936119914057 -0.5261200070381165 -1.0916800498962402 3.697799921035767 4.3810200691223145 38.02238219009024 30.0 1.0 no 12513 chrXIV_707851 31783 essential YNR046W 63 + AACTTCCCCCTACAGTACGA N|22|K silent|AAC>AAT|N|22 F|23|L silent|TTC>TTT|F|23 TRM112 TRna Methyltransferase 135.0 0 0 0 0 -0.7163792128508918 P53738 0.9265509843826294 0.924910008907318 0.014512668363749981 0.02404014579951763 -0.1202000007033348 1.3602399826049805 -1.425052046775818 53.805326551092655 50.0 1.0 no 12514 chrXIV_707857r 31785 essential YNR046W 72 - TTGCTGCCGTCGTACTGTAG S|30|T S|30|N G|29|A G|29|D TRM112 TRna Methyltransferase 135.0 0 0 0 0 -0.4164726020601249 P53738 0.9531499743461608 0.9555479884147644 0.951856017112732 0.9471049904823304 0.16315802931785586 0.11061251908540726 0.04225803166627884 1.0 0.2055799961090088 0.349839985370636 -0.21639999747276306 1.573539972305298 54.71906832335549 55.00000000000001 1.0 no 12515 chrXIV_707874 31787 essential YNR046W 86 + CAGCAAATGCCAATTGGTAC S|30|R silent|AGC>AGT|S|30 TRM112 TRna Methyltransferase 135.0 0 0 0 0 0.2979347216421724 P53738 0.9441919922828674 0.11194520443677902 0.25699999928474426 44.84506089300226 45.0 1.0 no 12516 chrXIV_708088 31797 essential YNR046W 300 + CTACAGACGTCCATTGCCGA Q|102|E Q|102|* TRM112 TRna Methyltransferase 135.0 0 0 0 0 -0.2944240390514199 P53738 0.9446460008621216 1.0 1.6053800582885742 53.40398562159476 55.00000000000001 1.0 no 12517 chrXIV_723616 31799 essential YNR054C 671 - CCTGTCTGATATCGTTCTCG Q|230|H silent|CAG>CAA|Q|230 R|229|T R|229|K ESF2 Eighteen S rRNA Factor 2 316.0 0 0 0 0 0.4266442637480697 P53743 0.9449650049209596 0.922694981098175 0.9502609968185424 0.009202827699482441 0.0 0.0 50.92474755781853 50.0 0.0 no 12518 chrXIV_723658 31800 essential YNR054C 629 - CTGCCCATTTGAAACCTGGG A|216|P A|216|T W|215|C W|215|* ESF2 Eighteen S rRNA Factor 2 316.0 0 0 0 0 -2.7226235040183275 P53743 0.9451119899749756 0.9337720274925232 0.8764719963073729 0.20901881158351895 0.4020988047122955 0.0 52.48693045051101 55.00000000000001 0.0 yes 12519 chrXIV_723717r 31802 essential YNR054C 567 + AACATTATTGGTGGCAAGAA N|190|K silent|AAC>AAT|N|190 ESF2 Eighteen S rRNA Factor 2 316.0 0 0 0 0 0.049947113407680384 P53743 0.9238790273666382 0.03608647361397743 40.14314237933485 35.0 0.0 no 12520 chrXIV_723729r 31803 essential YNR054C 555 + ACGTTGAACGGGAACATTAT T|186|R T|186|M ESF2 Eighteen S rRNA Factor 2 316.0 0 0 0 0 -0.22281350383055493 P53743 0.9317550063133241 0.9340829849243164 0.006683179643005133 0.003655304200947285 41.354998897788285 40.0 0.0 no 12521 chrXIV_723746 31804 essential YNR054C 541 - CAACGTCTCCGCACACAATT silent|ACG>ACC|T|186 silent|ACG>ACA|T|186 E|185|D silent|GAG>GAA|E|185 ESF2 Eighteen S rRNA Factor 2 316.0 0 0 0 0 -0.9473735845277348 P53743 0.9335240125656128 0.57845538854599 48.8331515585071 50.0 0.0 no 12522 chrXIV_723894r 31806 essential YNR054C 390 + AGACAAATATTAACTCGTTT Q|132|E Q|132|* ESF2 Eighteen S rRNA Factor 2 316.0 0 0 0 0 0.019859329794358616 P53743 0.9446460008621216 0.3580460548400879 34.966445695218965 25.0 0.0 no 12523 chrXIV_724036r 31811 essential YNR054C 248 + AGCTTCGTCCACCACTTCAC A|84|G A|84|V S|85|W S|85|L ESF2 Eighteen S rRNA Factor 2 316.0 0 0 0 0 0.741594501033295 P53743 0.9672009944915771 0.9664270281791688 0.9502170085906982 0.9594640135765076 0.3879230618476868 0.2849975824356079 0.02118794061243534 0.3126641511917114 56.92855803726843 55.00000000000001 0.0 no 12524 chrXIV_724089r 31812 essential YNR054C 195 + GAACAACCAGATAAAGAGAA Q|67|E Q|67|* P|68|A P|68|S ESF2 Eighteen S rRNA Factor 2 316.0 0 0 0 0 -1.115536462073738 P53743 1.0036499500274658 1.0013899803161619 0.9935989975929259 1.0 0.8291347026824951 0.8176975846290588 34.6875475621992 35.0 0.0 no 12525 chrXV_44972r 31814 essential YOL149W 37 - TCTATAGAATTCTAACTGTG R|19|T R|19|K DCP1 mRNA DeCaPping 231.0 0 1 0 0 0.480401144800184 Q12517 0.4108637869358063 1.0 0.352618008852005 0.04579799994826317 0.0697999969124794 -0.07959999889135361 36.28031455295496 30.0 1.0 no 12526 chrXV_44998 31815 essential YOL149W 60 + GCTTTGAATTTCAACGTTAT A|21|G A|21|V DCP1 mRNA DeCaPping 231.0 0 1 0 0 -0.16385203461252856 Q12517 0.08496159315109253 0.0957656428217888 0.13098999857902527 0.8518319725990295 0.27399998903274536 0.6169999837875366 40.248894337657134 30.0 1.0 no 12527 chrXV_45062 31816 essential YOL149W 124 + CACATGCGTCACTGTATAAA H|43|D H|43|Y A|44|G A|44|V DCP1 mRNA DeCaPping 231.0 0 0 0 0 0.646616998419489 Q12517 0.08730295300483704 0.5682071447372437 0.0610555112361908 0.03602324426174164 0.9823740124702454 0.13374599814414978 1.89709997177124 1.1152499914169312 1.350600004196167 1.6109999418258667 0.5971770286560059 -1.8797636032104488 42.715505289558735 40.0 1.0 no 12528 chrXV_45063 31817 essential YOL149W 125 + ACATGCGTCACTGTATAAAT H|43|D H|43|Y A|44|G A|44|V DCP1 mRNA DeCaPping 231.0 0 0 0 0 -0.8415097590914873 Q12517 0.08730295300483704 0.5682071447372437 0.0610555112361908 0.03602324426174164 0.9823740124702454 0.13374599814414978 1.89709997177124 1.1152499914169312 1.350600004196167 1.6109999418258667 0.5971770286560059 -1.8797636032104488 41.4348877197375 35.0 1.0 no 12529 chrXV_45111 31818 essential YOL149W 173 + ACTAGAATATCAAGGTGTTT L|59|V silent|CTA>TTA|L|59 DCP1 mRNA DeCaPping 231.0 0 0 0 0 0.1857774592546226 Q12517 0.19845907390117645 1.6182420253753662 1.384600043296814 1.4949536323547363 38.76625142579656 30.0 1.0 no 12530 chrXV_45413r 31824 essential YOL149W 478 - TCTTTTATTTACGACACTAT R|166|T R|166|K DCP1 mRNA DeCaPping 231.0 0 1 0 0 0.4108712252519211 Q12517 0.4097253382205963 0.3780515491962433 2.4560019969940186 1.3058799505233765 1.843000054359436 0.8140000104904175 38.61416177773515 25.0 1.0 no 12531 chrXV_46286r 31825 high_effect YOL148C 1266 + TCCAGTTCCAACGGGGTACG silent|TCC>TCG|S|423 silent|TCC>TCT|S|423 S|423|C S|423|F SPT20 SuPpressor of Ty 604.0 0 0 0 0 0.3814741905199661 P50875 0.945252001285553 0.9294660091400146 0.1075604036450386 0.2527502477169037 54.70088677032754 60.0 0.0 no 12532 chrXV_46293r 31826 high_effect YOL148C 1259 + TGCTAGCTCCAGTTCCAACG A|421|G A|421|V S|422|R silent|AGC>AGT|S|422 SPT20 SuPpressor of Ty 604.0 0 0 0 0 -0.2566573178461929 P50875 0.9484469890594482 0.9504740238189696 0.9417110085487366 0.5109740495681763 0.38830605149269104 0.5551144480705261 54.772884823251154 55.00000000000001 0.0 no 12533 chrXV_46294r 31827 high_effect YOL148C 1258 + TTGCTAGCTCCAGTTCCAAC A|421|G A|421|V SPT20 SuPpressor of Ty 604.0 0 0 0 0 0.7273832791678823 P50875 0.9484469890594482 0.9504740238189696 0.5109740495681763 0.38830605149269104 54.293101908985996 50.0 0.0 no 12534 chrXV_46312 31828 high_effect YOL148C 1243 - AGCAATCTCCATCGCATTCT A|421|P A|421|T E|419|D silent|GAG>GAA|E|419 SPT20 SuPpressor of Ty 604.0 0 0 0 0 0.8286990600120286 P50875 0.9573720097541808 0.9523990154266356 0.94931298494339 0.3174053430557251 0.6114593744277954 0.6177168488502502 51.88133357142368 45.0 0.0 no 12535 chrXV_46320r 31829 high_effect YOL148C 1232 + TTCGTTAACCAAGAATGCGA S|412|W S|412|L SPT20 SuPpressor of Ty 604.0 0 0 0 0 0.5238570974696939 P50875 0.9288619756698608 0.9298099875450134 0.035289548337459564 0.3791821897029877 42.57245354956313 40.0 0.0 no 12536 chrXV_46403 31830 high_effect YOL148C 1152 - TCATAATTTGAACTATGTTG E|391|Q E|391|K SPT20 SuPpressor of Ty 604.0 0 0 0 0 1.002332412596584 P50875 0.956179976463318 0.9475290179252625 0.0 0.0 34.31683114997901 25.0 0.0 no 12537 chrXV_46524r 31831 high_effect YOL148C 1028 + AGCTTTTTCAGAACCTCATT A|344|G A|344|V SPT20 SuPpressor of Ty 604.0 0 0 0 0 -0.23785033518586565 P50875 0.9484469890594482 0.9504740238189696 0.2618497312068939 0.1900048851966858 46.5638686926435 35.0 0.0 no 12538 chrXV_46525r 31832 high_effect YOL148C 1027 + CAGCTTTTTCAGAACCTCAT A|344|G A|344|V SPT20 SuPpressor of Ty 604.0 0 0 0 0 0.840438036758931 P50875 0.9484469890594482 0.9504740238189696 0.2618497312068939 0.1900048851966858 47.60549542475917 40.0 0.0 no 12539 chrXV_46556 31833 high_effect YOL148C 999 - AACATGTCTCGGTGCTCATA M|339|I M|339|I SPT20 SuPpressor of Ty 604.0 0 0 0 0 0.4652042426412741 P50875 0.9553959965705872 0.9553959965705872 0.4165994822978973 0.4165994822978973 49.21408365374964 45.0 0.0 no 12540 chrXV_46591 31834 high_effect YOL148C 964 - ACTTAGTGACAAGTTCCTCT S|328|T S|328|N SPT20 SuPpressor of Ty 604.0 0 1 0 0 -0.27638228781056906 P50875 0.9512869715690612 0.9536849856376648 0.43973079323768616 0.3832979798316956 47.70807426656444 40.0 0.0 no 12541 chrXV_46721 31835 high_effect YOL148C 834 - AACAATGTTCGATATACTCT L|284|F silent|TTG>TTA|L|284 SPT20 SuPpressor of Ty 604.0 0 0 0 0 -1.2853817455693743 P50875 0.9587849974632264 0.019141463562846184 38.32886793634162 30.0 0.0 no 12542 chrXV_46758r 31836 high_effect YOL148C 794 + CGCAAACACAGCAAATAAGA A|266|G A|266|V N|267|K silent|AAC>AAT|N|267 SPT20 SuPpressor of Ty 604.0 0 0 0 0 0.1867637235830909 P50875 0.9484469890594482 0.9504740238189696 0.9439849853515624 0.428047776222229 0.29318979382514954 0.8529869318008423 38.109182933026545 40.0 0.0 no 12543 chrXV_46796r 31838 high_effect YOL148C 756 + CAACCATCCGAACCTAATAG P|254|A P|254|S P|254|R P|254|L SPT20 SuPpressor of Ty 604.0 0 0 0 0 -0.5676439817074821 P50875 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.4952451288700104 0.6706735491752625 0.2731887996196747 0.1626235842704773 43.99130891829515 45.0 0.0 no 12544 chrXV_46807 31839 high_effect YOL148C 748 - TTCGGATGGTTGTTGAATCT E|256|Q E|256|K SPT20 SuPpressor of Ty 604.0 0 0 0 0 -0.2257637289903125 P50875 0.956179976463318 0.9475290179252625 0.5921794772148132 0.9182187914848328 45.75093697780835 40.0 0.0 no 12545 chrXV_46902 31840 high_effect YOL148C 653 - TGACATCAACTGTATTAGTA V|224|L V|224|I D|223|H D|223|N SPT20 SuPpressor of Ty 604.0 0 0 0 0 0.6447496353098265 P50875 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 0.16078990697860718 0.6260337829589844 0.04737691953778267 0.1456642895936966 38.75132736850895 30.0 0.0 no 12546 chrXV_46975r 31841 high_effect YOL148C 577 + ATGCTATTATGGAAGTCTTA A|194|G A|194|V SPT20 SuPpressor of Ty 604.0 0 0 0 0 0.2614520987222177 P50875 0.9484469890594482 0.9504740238189696 0.17477776110172272 0.06789617985486984 40.87637563002107 30.0 0.0 no 12547 chrXV_46974r 31842 high_effect YOL148C 578 + TGCTATTATGGAAGTCTTAA A|194|G A|194|V SPT20 SuPpressor of Ty 604.0 0 0 0 0 -0.005630436818178986 P50875 0.9484469890594482 0.9504740238189696 0.17477776110172272 0.06789617985486984 39.43409492802817 30.0 0.0 no 12548 chrXV_47035 31844 high_effect YOL148C 520 - TTTCAAAGTTTCGTTATTTT L|179|F silent|TTG>TTA|L|179 SPT20 SuPpressor of Ty 604.0 0 0 0 0 0.5986532278721359 P50875 0.9587849974632264 0.032074999064207084 37.246801642908395 20.0 0.0 no 12549 chrXV_47216 31846 high_effect YOL148C 339 - ACAAAATTGTAAAGTCTTTT V|120|L V|120|M SPT20 SuPpressor of Ty 604.0 0 0 0 0 0.8033138367241216 P50875 0.9539830088615416 0.9587630033493042 0.2225688099861145 0.06972712278366089 32.39769982124995 20.0 0.0 no 12550 chrXV_47230 31847 high_effect YOL148C 325 - TCTTTTAGGTCTTTTGTTTA R|115|T R|115|K SPT20 SuPpressor of Ty 604.0 0 0 0 0 1.2865138210337708 P50875 0.932735025882721 0.955805003643036 0.036517813801765435 0.35191023349761963 43.1505863981614 25.0 0.0 no 12551 chrXV_47277r 31848 high_effect YOL148C 275 + GCAAGCACTCCAAAACTATG Q|93|E Q|93|* A|94|G A|94|V SPT20 SuPpressor of Ty 604.0 0 0 0 0 -0.13988449739924586 P50875 0.9590039849281312 0.9484469890594482 0.9504740238189696 0.06402760744094849 0.4173246324062347 0.27842438220977783 43.34868903879989 45.0 0.0 no 12552 chrXV_47411 31849 high_effect YOL148C 144 - TTACTGTTTGTCCTCATAAC S|54|T S|54|N SPT20 SuPpressor of Ty 604.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.4344279026625649 P50875 0.9512869715690612 0.9536849856376648 0.2649036645889282 0.6820284128189087 44.05016362233448 35.0 0.0 no 12553 chrXV_47489r 31855 high_effect YOL148C 63 + CCATCCAATATGGGTTCGCC P|22|R P|22|L S|23|C S|23|F SPT20 SuPpressor of Ty 604.0 0 0 0 0 0.13260765095646526 P50875 0.9432820081710817 0.9430609941482544 0.945252001285553 0.9294660091400146 55.021123278210716 55.00000000000001 0.0 no 12554 chrXV_47498r 31856 high_effect YOL148C 54 + AACGCAACACCATCCAATAT N|19|K silent|AAC>AAT|N|19 A|20|G A|20|V SPT20 SuPpressor of Ty 604.0 0 0 0 0 0.06783141797768166 P50875 0.9439849853515624 0.9484469890594482 0.9504740238189696 44.28336531690013 40.0 0.0 no 12555 chrXV_47499r 31857 high_effect YOL148C 53 + GAACGCAACACCATCCAATA N|19|K silent|AAC>AAT|N|19 A|20|G A|20|V SPT20 SuPpressor of Ty 604.0 0 0 0 0 -0.2592035722598892 P50875 0.9439849853515624 0.9484469890594482 0.9504740238189696 45.340605782222326 45.0 0.0 no 12556 chrXV_48998r 31862 essential YOL146W 137 - TTCTTGCTAACCATAGTGGC R|52|T R|52|K A|51|P A|51|T PSF3 Partner of Sld Five 194.0 0 0 0 0 -1.1327721652094431 Q12146 0.913004994392395 0.9405699968338012 0.9448080062866212 0.9334689974784852 0.28841036558151245 0.6272286772727966 0.02063290774822235 0.023468563333153725 7.123199939727782 4.088200092315674 49.753114401674225 45.0 1.0 no 12557 chrXV_49022r 31863 essential YOL146W 161 - CGTCACCACCCACAATTGCA D|60|H D|60|N G|59|A G|59|D PSF3 Partner of Sld Five 194.0 0 0 0 0 1.1469559344594833 Q12146 0.9307199716567992 0.9436259865760804 0.932515025138855 0.9277639985084534 0.02297194674611092 0.045922636985778816 1.0 0.10182738304138184 2.5887999534606934 2.314199924468994 54.72196511052728 55.00000000000001 1.0 no 12558 chrXV_49092r 31864 essential YOL146W 231 - ACTTTCGTAGAAAACATATC V|84|L V|84|I silent|ACG>ACC|T|82 silent|ACG>ACA|T|82 PSF3 Partner of Sld Five 194.0 0 0 0 0 -0.05207403758049784 Q12146 0.9567329883575441 0.9644020199775696 0.03956564515829086 0.35955664515495295 -2.1415998935699463 -0.483599990606308 35.50782389833938 30.0 1.0 no 12559 chrXV_49118 31866 essential YOL146W 254 + GAACGCTATAAAGACCGATC N|86|K silent|AAC>AAT|N|86 A|87|G A|87|V PSF3 Partner of Sld Five 194.0 0 0 0 0 -0.3933755829183221 Q12146 0.9259759783744812 0.9672009944915771 0.9664270281791688 0.0 0.0 0.0 1.1416000127792358 0.0658000037074089 1.0457999706268308 0.14339999854564667 41.32159411900176 45.0 1.0 no 12560 chrXV_49174 31868 essential YOL146W 310 + TCTTCAGTCTAGCCATAAAA F|104|L silent|TTC>TTT|F|104 F|105|L silent|TTC>TTT|F|105 PSF3 Partner of Sld Five 194.0 0 0 0 0 0.8441284837301677 Q12146 0.9225289821624756 0.9255880117416382 0.0222286693751812 0.29534807801246643 3.3443999290466313 -0.5077999830245972 0.3240000009536743 -0.2838000059127808 43.16557730882504 35.0 1.0 no 12561 chrXV_49186r 31869 essential YOL146W 325 - AAACAACATTATCCATTTTA L|114|F silent|TTG>TTA|L|114 M|113|I M|113|I PSF3 Partner of Sld Five 194.0 0 0 0 0 0.29812833839590136 Q12146 0.9558500051498412 0.9415569901466371 0.9415569901466371 0.021693730726838112 0.29850220680236816 0.29850220680236816 0.08760000020265579 2.474800109863281 2.474800109863281 35.01547563872799 20.0 1.0 no 12562 chrXV_49296 31872 essential YOL146W 432 + GATCTCAATGCAGACTCGAC L|146|V L|146|F silent|CTC>CTG|L|146 silent|CTC>CTT|L|146 PSF3 Partner of Sld Five 194.0 0 0 0 0 -0.03337007134070813 Q12146 0.9530839920043944 0.960648000240326 0.5816904902458191 0.33166879415512085 0.25 0.0560000017285347 46.36214120036203 50.0 1.0 no 12563 chrXV_53231 31874 essential YOL144W 133 + ACTTTGCATTTATCGATATA H|45|Q silent|CAC>CAT|H|45 A|47|G A|47|V NOP8 NucleOlar Protein 484.0 0 0 0 0 0.8243199014294719 Q08287 0.5349177718162537 0.1735738217830658 0.016446316614747047 39.298525237228944 25.0 1.0 no 12564 chrXV_53515r 31876 essential YOL144W 420 - CTCAATTGACTCCTTTTTCT L|146|F silent|TTG>TTA|L|146 NOP8 NucleOlar Protein 484.0 0 0 0 0 0.3862372016365467 Q08287 0.03603939712047577 46.073116401828706 35.0 1.0 no 12565 chrXV_53545 31877 essential YOL144W 447 + ACATTCAGGATCAATGTCAA T|150|R T|150|I F|151|L silent|TTC>TTT|F|151 NOP8 NucleOlar Protein 484.0 0 0 0 0 -0.0282719390877214 Q08287 0.0 0.0 0.0 41.25672744740069 35.0 1.0 no 12566 chrXV_53586 31878 essential YOL144W 488 + ATGCTATAAGACTAAATTAT C|164|W silent|TGC>TGT|C|164 NOP8 NucleOlar Protein 484.0 0 0 0 0 0.6837351174404955 Q08287 0.0 32.324994416951945 20.0 1.0 no 12567 chrXV_53587 31879 essential YOL144W 489 + TGCTATAAGACTAAATTATG C|164|W silent|TGC>TGT|C|164 NOP8 NucleOlar Protein 484.0 0 0 0 0 -0.2731220854714117 Q08287 0.0 32.37704202336545 25.0 1.0 no 12568 chrXV_53645 31880 essential YOL144W 547 + ACAAGTTTACAAATAATTTC Y|183|* silent|TAC>TAT|Y|183 NOP8 NucleOlar Protein 484.0 0 0 0 0 0.29928930088594835 Q08287 30.836854201108967 20.0 1.0 no 12569 chrXV_53653 31881 essential YOL144W 555 + ACAAATAATTTCTGGAAAAA T|186|R T|186|I NOP8 NucleOlar Protein 484.0 0 0 0 0 -0.3633783840400464 Q08287 0.05958789587020874 0.6518241167068481 29.153474590357863 20.0 1.0 no 12570 chrXV_53679 31882 essential YOL144W 581 + CAACCACATTGTCGATAGAT N|195|K silent|AAC>AAT|N|195 H|196|D H|196|Y NOP8 NucleOlar Protein 484.0 0 0 0 0 0.5087193818073736 Q08287 0.0731751024723053 0.0 0.0 43.35931915103816 40.0 1.0 no 12571 chrXV_53720 31883 essential YOL144W 622 + AAACTGTTCGATTCAAAAAT T|209|S T|209|I NOP8 NucleOlar Protein 484.0 0 0 0 0 0.4447327799036609 Q08287 1.0 0.13376328349113464 32.762351220417706 25.0 1.0 no 12572 chrXV_53881r 31886 essential YOL144W 786 - TCCGAATCATTCAACGTCAT silent|TCG>TCC|S|268 silent|TCG>TCA|S|268 D|269|H D|269|N NOP8 NucleOlar Protein 484.0 0 0 0 1 -0.4606404498585169 Q08287 0.036957841366529465 0.2883678674697876 44.77268685530101 40.0 1.0 no 12573 chrXV_53682r 31889 essential YOL144W 587 - AATCCAATCTATCGACAATG D|202|H D|202|N L|201|F silent|TTG>TTA|L|201 NOP8 NucleOlar Protein 484.0 0 0 0 0 0.19310589477596665 Q08287 0.0 0.0 0.0 38.788763587267105 35.0 1.0 no 12574 chrXV_54091r 31893 essential YOL144W 996 - CCAATTTCCTTGGTGAAAGT G|339|R G|339|S NOP8 NucleOlar Protein 484.0 0 0 0 0 0.7979851990108453 Q08287 0.5405699014663696 0.7518923282623291 45.884069301670024 40.0 1.0 no 12575 chrXV_54097 31894 essential YOL144W 999 + TTCACCAAGGAAATTGGTCA F|334|L silent|TTC>TTT|F|334 T|335|S T|335|I NOP8 NucleOlar Protein 484.0 0 0 0 0 0.19625540200844926 Q08287 0.0 0.2410779446363449 0.023004425689578056 43.984689461666676 40.0 1.0 no 12576 chrXV_54147 31895 essential YOL144W 1049 + AAACCTATTCAACCCCAACG N|351|K silent|AAC>AAT|N|351 L|352|V silent|CTA>TTA|L|352 NOP8 NucleOlar Protein 484.0 0 0 0 0 -0.3589620545655612 Q08287 0.4678807854652405 0.0 45.94757093847949 45.0 1.0 no 12577 chrXV_54159r 31896 essential YOL144W 1064 - ATACAGGTTCTGCCTCGTTG V|361|L V|361|I NOP8 NucleOlar Protein 484.0 0 0 0 0 -0.2555279098953258 Q08287 0.3018720746040344 0.20263718068599698 53.06207595057544 50.0 1.0 no 12578 chrXV_55599 31901 essential YOL142W 41 + CCCTACTACACCTGTTAAAC P|15|R P|15|L P|15|A P|15|S RRP40 Ribosomal RNA Processing 240.0 0 0 0 0 0.8375232853855327 Q08285 0.3367164134979248 0.20419541001319885 0.6315085291862488 1.0 0.39524000883102417 1.0647599697113037 1.0465600490570068 1.1972399950027466 47.20708659255114 45.0 1.0 no 12579 chrXV_55600r 31903 essential YOL142W 45 - CCCAGTTTAACAGGTGTAGT silent|CTG>CTC|L|21 silent|CTG>CTA|L|21 G|22|R G|22|S RRP40 Ribosomal RNA Processing 240.0 0 0 0 0 -1.7444069323602198 Q08285 0.0 0.0 1.184399962425232 2.3984599113464355 50.81078836774304 45.0 1.0 no 12580 chrXV_55642r 31905 essential YOL142W 87 - GGTCGTATTTCTTGAGTATT R|35|P R|35|Q RRP40 Ribosomal RNA Processing 240.0 0 0 0 0 0.6147172247987119 Q08285 0.2818937599658966 0.4970259070396423 4.495120048522949 0.8675600290298462 45.47428208231639 35.0 1.0 no 12581 chrXV_55663r 31906 essential YOL142W 108 - TGCAAAACACCTGTATTAAC L|42|F silent|TTG>TTA|L|42 RRP40 Ribosomal RNA Processing 240.0 0 0 0 0 -4.627293884757086 Q08285 0.15667730569839478 0.8676999807357788 3.752579927444458 38.65219768208897 35.0 1.0 yes 12582 chrXV_55691r 31907 essential YOL142W 136 - AACACCACTCTTACCCTTAG V|52|L V|52|I G|51|A G|51|D RRP40 Ribosomal RNA Processing 240.0 0 0 0 0 -0.14352069735198875 Q08285 0.3791300654411316 0.2789942324161529 0.843194305896759 0.5805565714836121 -0.6315000057220459 -0.5546600222587585 2.4830400943756104 2.018239974975586 -0.6751199960708618 -0.8038200139999391 49.366965273441046 45.0 1.0 no 12583 chrXV_55791 31908 essential YOL142W 233 + GACATTTTCAGATAGCTATA T|79|R T|79|I RRP40 Ribosomal RNA Processing 240.0 0 0 0 0 -0.10284699399583007 Q08285 0.4400041103363037 0.08785822242498398 -0.3217400014400482 -0.4157800078392029 40.20914705076552 30.0 1.0 no 12584 chrXV_55882 31910 essential YOL142W 324 + AACAGGCCAACTTTGCAAGT N|109|K silent|AAC>AAT|N|109 P|111|A P|111|S RRP40 Ribosomal RNA Processing 240.0 0 0 0 0 1.2357804106587416 Q08285 0.0 0.14491315186023712 0.06462054699659348 -0.02563999965786934 1.833080053329468 1.9778399467468264 0.37619999051094055 1.7098000049591064 2.72379994392395 47.860322736704006 45.0 1.0 no 12585 chrXV_55972 31912 essential YOL142W 414 + TCAACTACAGGACGCGATGC S|139|* S|139|L T|140|S T|140|I RRP40 Ribosomal RNA Processing 240.0 0 0 0 0 -1.779551860845474 Q08285 0.01739826612174511 0.10860025882720947 0.055091436952352524 0.5776799917221069 0.0006000000284984707 0.6972399950027466 -0.21612000465393064 0.18223999440670013 48.28236326053201 55.00000000000001 1.0 no 12586 chrXV_55978 31913 essential YOL142W 420 + ACAGGACGCGATGCTGGTTT T|141|R T|141|I R|143|G R|143|C RRP40 Ribosomal RNA Processing 240.0 0 0 0 0 0.26079111712391245 Q08285 0.00646463967859745 0.007192728575319052 0.008109692484140396 0.0010816891444846988 -0.8544600009918213 -0.6357200145721436 -0.027219999581575397 0.22360000014305115 -1.2823400497436523 -1.102239966392517 52.99165356322578 55.00000000000001 1.0 no 12587 chrXV_56070 31914 essential YOL142W 512 + CTTCCCGTTATTAAAAGTGT F|172|L silent|TTC>TTT|F|172 P|173|A P|173|S RRP40 Ribosomal RNA Processing 240.0 0 0 0 0 0.6137581410495433 Q08285 0.6392989754676819 0.7071677446365356 0.7890170216560364 1.3497200012207031 2.053580045700073 1.8315800428390503 1.2310400009155271 43.72503970899726 35.0 1.0 no 12588 chrXV_60652 31917 essential YOL139C 353 - CAGCACCTTTTCCTCTAAGT A|124|P A|124|T G|123|A G|123|D CDC33 Cell Division Cycle 213.0 0 1 0 0 -0.0037679771635780062 P07260 0.9532269835472108 0.965637981891632 0.9871050119400024 0.9206500053405762 0.2486465722322464 0.30744269490242004 0.7113460898399353 0.6299375295639038 0.16419999301433566 0.5748000144958496 3.3422000408172607 3.1487998962402344 3.767859935760498 -0.1546200066804886 52.63512477212595 45.0 0.0 no 12589 chrXV_60680 31918 essential YOL139C 325 - CCATTTACCACCTTTAGCAT W|115|S W|115|* CDC33 Cell Division Cycle 213.0 0 1 0 0 -0.8970256395032399 P07260 0.597661018371582 0.007864397019147873 -0.5022000074386597 50.822853175527364 40.0 0.0 no 12590 chrXV_60741 31920 essential YOL139C 264 - ACGTGGTAATCTGATTTCAA V|95|L V|95|I CDC33 Cell Division Cycle 213.0 0 0 0 0 -0.023534051957741053 P07260 0.9967210292816162 0.9260240197181702 1.0 0.1246347874403 2.789599895477295 1.5700000524520874 41.6227434522595 35.0 0.0 no 12591 chrXV_60851 31922 essential YOL139C 154 - CCACGACTCAGATTTATCGA silent|TCG>TCC|S|57 silent|TCG>TCA|S|57 W|58|S W|58|* CDC33 Cell Division Cycle 213.0 0 0 0 0 -0.05389305937628208 P07260 0.6535450220108032 0.0 1.687199950218201 1.4247000217437744 46.373870109343045 45.0 0.0 no 12592 chrXV_60896r 31925 essential YOL139C 106 + AGCACCCATTGAACACCAAA H|37|D H|37|Y H|37|Q silent|CAC>CAT|H|37 CDC33 Cell Division Cycle 213.0 0 1 0 0 -0.9810350202693968 P07260 0.7105000019073486 0.7562739849090576 0.7152289748191833 0.0 0.0 0.0 0.2766000032424927 -0.8902000188827515 0.03220000118017197 0.5173000097274779 -0.4412600100040436 -0.213359996676445 0.02180001139640808 4.3063998222351065 -0.6656000018119812 47.562803276654854 45.0 0.0 no 12593 chrXV_60998 31926 essential YOL139C 7 - CTTCTTGCTAACTTCTTCAA K|8|N silent|AAG>AAA|K|8 CDC33 Cell Division Cycle 213.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.3403837329818015 P07260 0.9041759967803956 0.3404190242290497 1.3753999471664429 44.11204015705568 35.0 0.0 no 12594 chrXV_60800r 31927 essential YOL139C 202 + TCCAAACTGTTGAAGAATTT Q|69|E Q|69|* F|68|L silent|TTC>TTT|F|68 CDC33 Cell Division Cycle 213.0 0 0 0 0 0.4632546309456676 P07260 1.0250799655914309 0.8346920013427734 1.0 0.08031032979488373 1.047600030899048 -0.6291999816894531 2.4052000045776367 0.4541000127792358 1.1705999374389648 37.79945692033709 30.0 0.0 no 12595 chrXV_69755 31933 essential YOL135C 270 - AGTCCCATGCTCTCTAAATC G|96|A G|96|E G|96|R G|96|R MED7 MEDiator complex 222.0 0 0 0 0 0.3185849559757695 Q08278 0.9499930143356324 0.9438679814338684 0.941340982913971 0.941340982913971 0.0320894792675972 0.03820972517132759 0.022290175780653957 0.022290175780653957 50.382293637992404 45.0 0.0 no 12596 chrXV_69805r 31937 essential YOL135C 217 + ATCAGCAGTACCGAGCGTTT Q|74|E Q|74|* Q|75|E Q|75|* MED7 MEDiator complex 222.0 0 0 0 0 0.041158845608181886 Q08278 0.9590039849281312 0.9590039849281312 0.835688054561615 0.5970907211303711 0.2875199913978577 -0.15117999911308289 0.1652200073003769 53.26174234024489 50.0 0.0 no 12597 chrXV_69811 31939 essential YOL135C 214 - CGCTCGGTACTGCTGATTTT A|78|P A|78|T R|77|P R|77|Q MED7 MEDiator complex 222.0 0 0 0 0 0.22376274746655825 Q08278 0.9573720097541808 0.9523990154266356 0.9099509716033936 0.949662983417511 0.26439225673675537 0.4324583411216736 0.011193161830306051 0.03017432242631912 1.024399995803833 0.5259799957275391 -0.08408000320196153 0.16832000017166138 52.07855388592373 50.0 0.0 no 12598 chrXV_69818 31942 essential YOL135C 207 - TACTGCTGATTTTTGGGCAT Q|75|H silent|CAG>CAA|Q|75 Q|74|H silent|CAG>CAA|Q|74 MED7 MEDiator complex 222.0 0 0 0 0 -0.14536482348890634 Q08278 0.9570760130882264 0.9570760130882264 0.586176335811615 0.2521363198757172 0.4844200015068054 0.4261200129985809 0.4909400045871735 48.4762021362111 40.0 0.0 no 12599 chrXV_69821 31945 essential YOL135C 204 - TGCTGATTTTTGGGCATGGG Q|74|H silent|CAG>CAA|Q|74 MED7 MEDiator complex 222.0 0 0 0 0 -0.17165625481160462 Q08278 0.9570760130882264 0.2521363198757172 0.4261200129985809 51.558485398608866 50.0 0.0 no 12600 chrXV_69884 31946 essential YOL135C 141 - CTGCCGCCGTTACTGTTATT G|53|A G|53|D G|53|R G|53|S MED7 MEDiator complex 222.0 0 0 0 0 0.3969092882155051 Q08278 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.7976061701774597 0.628986120223999 0.5495047569274902 0.7562408447265625 54.94290865707126 50.0 0.0 no 12601 chrXV_69929 31947 essential YOL135C 96 - GCCTTCTTTTCTTTGTATTT K|38|N silent|AAG>AAA|K|38 A|39|P A|39|T MED7 MEDiator complex 222.0 0 0 0 0 0.4525127804944871 Q08278 0.9355990290641784 0.9573720097541808 0.9523990154266356 0.33751991391181946 0.25979775190353394 0.5291577577590942 0.05187999829649925 1.6570600271224976 0.4347400069236755 48.50420549767432 30.0 0.0 no 12602 chrXV_70387 31951 essential YOL133W 62 + CTCAAACCAAAGTGCGCCAG S|22|* S|22|L N|23|K silent|AAC>AAT|N|23 HRT1 High level expression Reduces Ty3 transposition 121.0 0 0 0 0 -4.865758629738083 Q08273 0.9298099875450134 0.9439849853515624 0.2722551226615906 1.0 48.66841661909427 55.00000000000001 1.0 yes 12603 chrXV_70403r 31952 essential YOL133W 81 - CTCTTCTTTTTGGTTTCCAC K|33|N silent|AAG>AAA|K|33 K|32|N silent|AAG>AAA|K|32 HRT1 High level expression Reduces Ty3 transposition 121.0 0 1 0 0 -0.6796440403773178 Q08273 0.9355990290641784 0.9355990290641784 0.2523621916770935 0.17381419241428375 -0.038600001484155655 0.23559999465942386 50.438929150391566 40.0 1.0 no 12604 chrXV_70446r 31954 essential YOL133W 124 - CCATGACCAAAACGCCACTG W|48|S W|48|* W|46|C W|46|* HRT1 High level expression Reduces Ty3 transposition 121.0 0 0 0 0 -2.111760852045254 Q08273 0.8858469724655151 0.8858469724655151 0.0 0.0005637644208036362 0.7242000102996826 0.7755600214004517 1.4052000045776367 1.6463000774383545 48.61982820189604 55.00000000000001 1.0 yes 12605 chrXV_70519 31955 essential YOL133W 194 + ATGCATTGAATGCCAGCCAA C|66|W silent|TGC>TGT|C|66 HRT1 High level expression Reduces Ty3 transposition 121.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.07888560045726366 Q08273 0.9286419749259948 0.0005719438195228577 49.85126271969477 45.0 1.0 no 12606 chrXV_70542r 31958 essential YOL133W 220 - TTCATTATCAGTGTCCGTCA E|80|Q E|80|K HRT1 High level expression Reduces Ty3 transposition 121.0 0 1 0 0 0.35150799452667364 Q08273 0.956179976463318 0.9475290179252625 0.06611426919698715 0.11237605661153792 -1.7860000133514404 -0.34439998865127563 50.11094297511517 40.0 1.0 no 12607 chrXV_70575r 31959 essential YOL133W 253 - AGCGTGATTACAGACACCCC A|91|P A|91|T HRT1 High level expression Reduces Ty3 transposition 121.0 0 1 0 0 -0.5924722810778905 Q08273 0.9573720097541808 0.9523990154266356 0.009669815190136431 0.03280673176050186 -0.5987200140953064 0.8913000226020813 53.88882243864669 55.00000000000001 1.0 no 12608 chrXV_74450 31960 essential YOL130W 50 + AAACTCACTGGCTAACACGA N|18|K silent|AAC>AAT|N|18 S|19|* S|19|L 0 1 0 0 -0.6284593321427262 Q08269 0.9439849853515624 0.9298099875450134 43.5439356569197 45.0 1.0 no 12609 chrXV_74550r 31966 essential YOL130W 153 - TCCTTGTTCTTCAATGTTGG K|57|N silent|AAG>AAA|K|57 E|58|Q E|58|K 0 0 0 0 -0.05848092988539255 Q08269 0.9355990290641784 0.956179976463318 0.9475290179252625 48.09793063354578 40.0 1.0 no 12610 chrXV_74585 31967 essential YOL130W 185 + CACTAAACCTTCTATTCCTA T|63|S T|63|I 0 0 0 0 -0.5843055062022005 Q08269 0.9491789937019348 0.9472420215606691 44.193164229964225 35.0 1.0 no 12611 chrXV_74636r 31970 essential YOL130W 239 - GTACGCTTCCCACATCCACA V|86|L V|86|I S|85|T S|85|N 0 1 0 0 0.992415963421548 Q08269 0.9539830088615416 0.9574310183525084 0.9512869715690612 0.9536849856376648 0.5741273164749146 1.0 0.558428168296814 0.7116805911064148 57.66991384412329 55.00000000000001 1.0 no 12612 chrXV_74740 31971 essential YOL130W 340 + CCATTTTAACTTCTAACGCG silent|GCC>GCG|A|114 silent|GCC>GCT|A|114 0 0 0 0 0.6616681027132308 Q08269 43.073147015555385 40.0 1.0 no 12613 chrXV_74767r 31973 essential YOL130W 370 - TGGCATGGAGTGGGCTAGTC M|129|I M|129|I 0 0 0 0 0.4180343504652111 Q08269 0.9553959965705872 0.9553959965705872 0.21403564512729645 0.21403564512729645 57.1022200810246 60.0 1.0 no 12614 chrXV_74776 31974 essential YOL130W 376 + CCCACTCCATGCCACATCAA H|127|D H|127|Y silent|GCC>GCG|A|126 silent|GCC>GCT|A|126 0 0 0 0 0.8284324151911099 Q08269 0.9473130106925964 0.9489949941635132 0.3213528394699097 1.0 56.9178987708193 55.00000000000001 1.0 no 12615 chrXV_74832r 31979 essential YOL130W 435 - CTCTTTACACCTACATCCTT K|151|N silent|AAG>AAA|K|151 0 0 0 0 0.43490666939413736 Q08269 0.9355990290641784 0.7175612449645996 49.85058150815138 40.0 1.0 no 12616 chrXV_74868 31980 essential YOL130W 468 + TCATCTTCTACTGCATCATC S|157|* S|157|L S|158|C S|158|F 0 0 0 0 -0.008908006692208106 Q08269 0.9298099875450134 0.945252001285553 0.9294660091400146 0.8268858194351196 0.17703723907470706 0.7014250159263611 47.58530120661186 40.0 1.0 no 12617 chrXV_74917r 31981 essential YOL130W 520 - CTTCGTAATAGGACTTGCCG silent|ACG>ACC|T|179 silent|ACG>ACA|T|179 0 0 0 0 -0.2027783137501952 Q08269 48.10416059298336 50.0 1.0 no 12618 chrXV_74978r 31984 essential YOL130W 581 - TATCAGATTTCGATTCGTGT D|200|H D|200|N 0 1 0 0 -0.07286380718890881 Q08269 0.9486550092697144 0.956179976463318 0.13179825246334076 0.5159538984298706 43.67675492335529 35.0 1.0 no 12619 chrXV_75070r 31987 essential YOL130W 673 - GCTTTTCGTCAGTAAAACTG S|231|T S|231|N silent|ACG>ACC|T|229 silent|ACG>ACA|T|229 1 Series([], Name: modification, dtype: object) 0 0 0 1.0028090872262263 Q08269 0.9512869715690612 0.9536849856376648 0.899013102054596 0.4792202115058899 42.28080559252129 40.0 1.0 no 12620 chrXV_75097r 31988 essential YOL130W 700 - ATCATCTGCATCCGATTTTT D|240|H D|240|N D|239|H D|239|N 0 1 0 0 0.4606241606405497 Q08269 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.1237579584121704 0.5365265607833862 0.17402249574661255 0.7921655774116516 47.568493198340995 35.0 1.0 no 12621 chrXV_75098r 31989 essential YOL130W 701 - CATCATCTGCATCCGATTTT D|240|H D|240|N D|239|H D|239|N 0 1 0 0 0.8162482699959138 Q08269 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.1237579584121704 0.5365265607833862 0.17402249574661255 0.7921655774116516 48.56602540753215 40.0 1.0 no 12622 chrXV_75234r 31992 essential YOL130W 837 - ACTCTGGTATGCAATTGTGG R|285|T R|285|K V|286|L V|286|I 0 0 0 0 -0.5473795045855887 Q08269 0.932735025882721 0.955805003643036 0.9539830088615416 0.9574310183525084 0.009496105834841728 0.13711044192314148 0.0632258877158165 1.0 47.34159626855626 45.0 1.0 no 12623 chrXV_75305 31994 essential YOL130W 905 + CGCGGAGAAGAGTCAATTTT A|303|G A|303|V 0 0 0 0 0.1749544731742042 Q08269 0.9484469890594482 0.9504740238189696 0.34684181213378906 0.27266478538513184 44.128235662701634 45.0 1.0 no 12624 chrXV_75342r 31995 essential YOL130W 945 - TTACTGTACTTCTGTTCGTT S|321|T S|321|N 0 0 0 0 -0.34196784986969275 Q08269 0.9512869715690612 0.9536849856376648 0.5914121270179749 0.5915498733520508 46.406068668954106 35.0 1.0 no 12625 chrXV_74993 31996 essential YOL130W 593 + ATCTGATACACACTCCAAGC S|199|C S|199|F 0 1 0 0 0.8351182193203361 Q08269 0.945252001285553 0.9294660091400146 0.0392686165869236 0.0621122308075428 46.78434040323492 45.0 1.0 no 12626 chrXV_75387 31997 essential YOL130W 987 + ACCAGCTCTACTTCCACTTC silent|ACC>ACG|T|330 silent|ACC>ACT|T|330 T|330|S T|330|I 0 0 0 0 0.2193932981388767 Q08269 0.9491789937019348 0.9472420215606691 0.8705331087112427 0.4955527782440186 55.29742585873834 50.0 1.0 no 12627 chrXV_75400r 31998 essential YOL130W 1003 - GGCAGCTGATGATCCCGAAG A|341|P A|341|T A|340|P A|340|T 0 1 0 0 -1.0839688771915397 Q08269 0.9573720097541808 0.9523990154266356 0.9573720097541808 0.9523990154266356 0.018913766369223598 0.03248796984553337 0.032216593623161316 0.03841457515954971 53.62758736269001 60.0 1.0 no 12628 chrXV_75421r 31999 essential YOL130W 1024 - AACTCTTGGTGTATATTTTA V|348|L V|348|I R|347|T R|347|K 0 1 0 0 -0.2665863807642497 Q08269 0.9539830088615416 0.9574310183525084 0.932735025882721 0.955805003643036 0.4389349818229675 0.2807545661926269 0.05508270114660263 0.7506909370422363 39.33409041480349 25.0 1.0 no 12629 chrXV_75488r 32003 essential YOL130W 1091 - GCTCGTCTTCCTTCTTTTCA E|370|Q E|370|K E|370|D silent|GAG>GAA|E|370 0 0 0 0 -0.17345124612262233 Q08269 0.956179976463318 0.9475290179252625 0.94931298494339 0.5506250858306885 0.8538014888763428 0.6211734414100647 56.19825748728056 45.0 1.0 no 12630 chrXV_75519 32004 essential YOL130W 1119 + ATCAAGCCTAGTTTACACCC I|374|M silent|ATC>ATT|I|374 P|376|A P|376|S 0 1 0 0 0.18217861831430526 Q08269 0.9598389863967896 0.9562489986419678 0.9498909711837769 0.11740072071552275 0.7131808400154114 0.8155466318130493 51.21352119123191 45.0 1.0 no 12631 chrXV_75531 32005 essential YOL130W 1131 + TTACACCCTGGTATATCTTT H|379|D H|379|Y H|379|Q silent|CAC>CAT|H|379 0 1 0 0 0.09540577266979904 Q08269 0.9473130106925964 0.9489949941635132 0.9588389992713928 0.6772240996360779 0.2647322714328766 0.6471436619758606 47.81990073223864 35.0 1.0 no 12632 chrXV_75584 32007 essential YOL130W 1184 + AAACATTCCATCCAATGACC N|396|K silent|AAC>AAT|N|396 0 0 0 0 -0.15086908840901234 Q08269 0.9439849853515624 0.6945176124572754 44.45687692977799 40.0 1.0 no 12633 chrXV_75698 32012 essential YOL130W 1298 + TATCCCTTCCTTAGTGTCTG I|434|M silent|ATC>ATT|I|434 P|435|A P|435|S 0 0 0 0 0.2751250146398487 Q08269 0.9598389863967896 0.9562489986419678 0.9498909711837769 0.02653630822896957 0.4202172160148621 0.38362863659858704 54.256381291494115 45.0 1.0 no 12634 chrXV_75726 32014 essential YOL130W 1326 + ACATTCTATGAATTATTCAG T|443|R T|443|I F|444|L silent|TTC>TTT|F|444 1 Series([], Name: modification, dtype: object) 0 0 0 0.8833566651586482 Q08269 0.9476869702339172 0.9472420215606691 0.9387490153312684 0.03940956294536591 0.028117958456277847 0.5017501711845398 35.381052820087525 25.0 1.0 no 12635 chrXV_75827r 32017 essential YOL130W 1430 - TATCTTCTGCAGTCAATGGA D|483|H D|483|N E|482|Q E|482|K 0 0 0 0 -0.6326490903435662 Q08269 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.0 0.0 0.0 0.0 46.55644834676138 40.0 1.0 no 12636 chrXV_75966 32019 essential YOL130W 1566 + TACATTGTTGTCTGTAGGTC Y|523|* silent|TAC>TAT|Y|523 0 0 0 0 0.4427239607583063 Q08269 47.02602222397292 40.0 1.0 no 12637 chrXV_76297r 32022 essential YOL130W 1900 - AGCTTCATCTTGGCATCTTT A|640|P A|640|T E|639|Q E|639|K 0 0 0 0 -0.3373936224726751 Q08269 0.9573720097541808 0.9523990154266356 0.956179976463318 0.9475290179252625 0.1580256074666977 0.4517982006072998 0.020947355777025226 0.016389142721891403 51.62211053580819 40.0 1.0 no 12638 chrXV_88015r 32025 essential YOL123W 174 - CTACTACTGTTGTTACTATT S|64|T S|64|N S|63|T S|63|N HRP1 Heterogenous nuclear RibonucleoProtein 534.0 0 1 0 0 -0.07933165545179141 Q99383 0.3502137064933777 0.2932887673377991 0.5831920504570007 0.5323694348335266 41.25194750808311 30.0 1.0 no 12639 chrXV_88050r 32026 essential YOL123W 209 - GCTTACTAGAAGATGTGTCT K|76|N silent|AAG>AAA|K|76 S|75|T S|75|N HRP1 Heterogenous nuclear RibonucleoProtein 534.0 0 0 0 0 -0.5199050418741069 Q99383 0.4907848536968231 0.5235688090324402 0.6329537034034729 44.99993752167825 40.0 1.0 no 12640 chrXV_88057 32027 essential YOL123W 213 + ACATCTTCTAGTAAGCAAGA T|72|R T|72|I S|73|C S|73|F HRP1 Heterogenous nuclear RibonucleoProtein 534.0 0 1 0 0 1.0252039807604896 Q99383 0.13495396077632904 0.29496583342552185 0.03948095813393593 0.02641077153384685 41.46521408977571 35.0 1.0 no 12641 chrXV_88103r 32028 essential YOL123W 262 - TTCATTCTTAGTGTCTTCAT E|94|Q E|94|K K|92|N silent|AAG>AAA|K|92 HRP1 Heterogenous nuclear RibonucleoProtein 534.0 0 0 0 0 -1.054938143955459 Q99383 0.6180393099784851 0.9290751814842224 0.5060322284698486 45.0691046086796 30.0 1.0 no 12642 chrXV_88168 32030 essential YOL123W 324 + GCTAGTTCTGCAGGACCTTC A|109|G A|109|V HRP1 Heterogenous nuclear RibonucleoProtein 534.0 0 0 0 0 0.1962166793087794 Q99383 0.5130169391632079 0.5428113341331482 56.814468817427546 55.00000000000001 1.0 no 12643 chrXV_88263 32031 essential YOL123W 419 + GCAAGTAACTCAAACCAAAG Q|141|E Q|141|* HRP1 Heterogenous nuclear RibonucleoProtein 534.0 0 0 0 0 0.28500044401925745 Q99383 0.8738890290260315 38.08359880664568 40.0 1.0 no 12644 chrXV_88277r 32032 essential YOL123W 436 - CGCTTTCGAACGTTCCTCTT A|152|P A|152|T silent|TCG>TCC|S|150 silent|TCG>TCA|S|150 HRP1 Heterogenous nuclear RibonucleoProtein 534.0 0 0 0 0 0.3719097330585683 Q99383 0.032208871096372604 0.041837196797132485 52.017524616559285 50.0 1.0 no 12645 chrXV_88326 32033 essential YOL123W 482 + GTTCATTGGTGGTCTGAATT F|162|L silent|TTC>TTT|F|162 HRP1 Heterogenous nuclear RibonucleoProtein 534.0 0 0 0 0 -1.0505741237611432 Q99383 0.0 0.6755999922752379 0.18219999969005585 47.31912195689273 40.0 1.0 no 12646 chrXV_88369 32034 essential YOL123W 525 + CGCGAATATTTTGGTAAGTA silent|CGC>CGG|R|176 silent|CGC>CGT|R|176 HRP1 Heterogenous nuclear RibonucleoProtein 534.0 0 0 0 0 0.6608451303302629 Q99383 40.41441484245115 35.0 1.0 no 12647 chrXV_88422r 32036 essential YOL123W 581 - CTCTAGATCTACCTGTTGCA R|200|T R|200|K HRP1 Heterogenous nuclear RibonucleoProtein 534.0 0 0 0 0 -1.0561956357532514 Q99383 0.0 0.0 1.8597999811172483 -0.1395999938249588 51.01924271849747 45.0 1.0 no 12648 chrXV_88423r 32037 essential YOL123W 582 - CCTCTAGATCTACCTGTTGC R|200|T R|200|K G|201|R G|201|R HRP1 Heterogenous nuclear RibonucleoProtein 534.0 0 0 0 0 -2.3858565013625155 Q99383 0.0 0.0 0.0 0.0 1.8597999811172483 -0.1395999938249588 3.4883999824523926 3.4883999824523926 53.634776916933966 50.0 1.0 yes 12649 chrXV_88471r 32042 essential YOL123W 630 - ACCACTTCATCAACACTAGA silent|GTG>GTC|V|216 silent|GTG>GTA|V|216 V|217|L V|217|I HRP1 Heterogenous nuclear RibonucleoProtein 534.0 0 0 0 0 0.7573987138535402 Q99383 0.2688024342060089 0.4008807837963104 -0.8176000118255615 -0.14659999310970304 -1.2563999891281128 -1.0032000541687012 45.16135096776634 40.0 1.0 no 12650 chrXV_88509r 32043 essential YOL123W 668 - GGTCGATAACTTTACCATCG D|229|H D|229|N HRP1 Heterogenous nuclear RibonucleoProtein 534.0 0 1 0 0 -3.8733452738323786 Q99383 0.0 0.0 -0.5641999840736389 -0.2362000048160553 45.481943020799754 45.0 1.0 yes 12651 chrXV_88681 32046 essential YOL123W 837 + ACCGGTCAATCAAGAGGTTT silent|ACC>ACG|T|280 silent|ACC>ACT|T|280 T|280|S T|280|I HRP1 Heterogenous nuclear RibonucleoProtein 534.0 0 0 0 0 -0.2051604801210408 Q99383 0.17130033671855927 0.006072368007153273 -0.15320000052452087 -0.7084000110626221 47.91799258387783 45.0 1.0 no 12652 chrXV_88682r 32047 essential YOL123W 841 - ACCAAAACCTCTTGATTGAC G|287|R G|287|S G|287|A G|287|D HRP1 Heterogenous nuclear RibonucleoProtein 534.0 0 0 0 0 -5.350137486616915 Q99383 0.0 0.0 0.0 0.0 22.81940078735352 6.014400005340576 3.7978000640869136 11.464200019836426 42.712894902279466 40.0 1.0 yes 12653 chrXV_88721r 32048 essential YOL123W 880 - AACTCTGTCAACGGCGTCAG V|300|L V|300|I R|299|T R|299|K HRP1 Heterogenous nuclear RibonucleoProtein 534.0 0 1 0 0 -0.2382001483497863 Q99383 0.0 0.0 0.01378774642944336 0.2941526472568512 2.3854000568389893 0.8677999973297119 0.5627999901771545 0.18539999425411224 -2.5927999019622803 -0.7301999926567078 49.728170472119636 55.00000000000001 1.0 no 12654 chrXV_88730r 32049 essential YOL123W 889 - ATTCTGACAAACTCTGTCAA Q|302|H silent|CAG>CAA|Q|302 HRP1 Heterogenous nuclear RibonucleoProtein 534.0 0 1 0 0 -0.9766410263393036 Q99383 0.06423206627368927 0.5109999775886536 40.610761758239455 35.0 1.0 no 12655 chrXV_88852 32052 essential YOL123W 1008 + AACAACATGAATCGTCGTGG N|337|K silent|AAC>AAT|N|337 N|338|K silent|AAC>AAT|N|338 HRP1 Heterogenous nuclear RibonucleoProtein 534.0 0 0 0 0 0.2600508161157098 Q99383 0.9545819759368896 0.3665662109851837 41.56007190628361 45.0 1.0 no 12656 chrXV_88902r 32055 essential YOL123W 1061 - TCATAGGGTTTTGATACATT M|360|I M|360|I HRP1 Heterogenous nuclear RibonucleoProtein 534.0 0 0 0 0 0.4106462673261017 Q99383 0.4124391376972199 0.4124391376972199 41.66179206553329 30.0 1.0 no 12657 chrXV_88909 32056 essential YOL123W 1065 + TATCAAAACCCTATGATGGG Q|357|E Q|357|* HRP1 Heterogenous nuclear RibonucleoProtein 534.0 0 0 0 0 0.3839530752316115 Q99383 0.6952166557312012 42.04537844070512 40.0 1.0 no 12658 chrXV_89040 32059 essential YOL123W 1196 + CCAACAACAAATGCAGCAAA Q|400|E Q|400|* Q|401|E Q|401|* HRP1 Heterogenous nuclear RibonucleoProtein 534.0 0 0 0 0 0.4631598991441199 Q99383 1.0 1.0 39.63904127736794 40.0 1.0 no 12659 chrXV_126154 32060 essential YOL102C 516 - TTCAAAGTTTGAAAGAATAA L|178|F silent|TTG>TTA|L|178 TPT1 tRNA 2'-PhosphoTransferase 230.0 0 0 0 0 0.6224521192127449 Q12272 0.0750717744231224 29.160542012575437 20.0 0.0 no 12660 chrXV_126235 32062 essential YOL102C 435 - CCCTTCGCGTGCAACATCCC K|151|N silent|AAG>AAA|K|151 G|152|R G|152|R TPT1 tRNA 2'-PhosphoTransferase 230.0 0 0 0 0 -0.4227452413665711 Q12272 0.6993890404701233 0.4511392712593079 0.4511392712593079 60.651310379613115 65.0 0.0 no 12661 chrXV_126253r 32067 essential YOL102C 414 + AATCATGTCCATTTATCGCC H|140|D H|140|Y TPT1 tRNA 2'-PhosphoTransferase 230.0 0 0 0 0 0.3137302383125494 Q12272 0.0 0.0 48.21433142389998 40.0 0.0 no 12662 chrXV_126334 32068 essential YOL102C 336 - GTTCCATGAATTAGTTCCTG G|118|A G|118|E G|118|R G|118|R TPT1 tRNA 2'-PhosphoTransferase 230.0 0 0 0 0 0.11867787506845427 Q12272 0.0 0.0 0.0 0.0 47.080765127844465 40.0 0.0 no 12663 chrXV_126298r 32069 essential YOL102C 369 + GTCATAAAGATTATTGAATC silent|GTC>GTG|V|124 silent|GTC>GTT|V|124 TPT1 tRNA 2'-PhosphoTransferase 230.0 0 0 0 0 0.10630900415272848 Q12272 32.49442795065596 25.0 0.0 no 12664 chrXV_126389r 32071 essential YOL102C 278 + ATCGATTCAGCCATCAGATG S|94|W S|94|L TPT1 tRNA 2'-PhosphoTransferase 230.0 0 0 0 0 0.2427678828075859 Q12272 0.02287556603550911 0.354270875453949 47.605479296089975 45.0 0.0 no 12665 chrXV_126457r 32073 essential YOL102C 210 + CGCTTTCATATAAAAACGTT silent|CGC>CGG|R|71 silent|CGC>CGT|R|71 H|73|D H|73|Y TPT1 tRNA 2'-PhosphoTransferase 230.0 0 0 0 0 1.1748756269671399 Q12272 0.5547620058059692 1.0 37.01903935030651 30.0 0.0 no 12666 chrXV_126624 32074 essential YOL102C 46 - AAGCAGATATGATAAAGCTT silent|CTG>CTC|L|21 silent|CTG>CTA|L|21 TPT1 tRNA 2'-PhosphoTransferase 230.0 0 0 0 0 0.7379222245057471 Q12272 37.10706845870982 30.0 0.0 no 12667 chrXV_133558r 32075 no_effect YOL098C 2258 + TTTCAACAAGTTTCATATTT F|754|L silent|TTC>TTT|F|754 N|755|K silent|AAC>AAT|N|755 SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 0.791354816566322 Q12496 0.9387490153312684 0.9439849853515624 0.9133995175361632 0.5767220258712769 36.010472740032135 20.0 0.0 no 12668 chrXV_133596 32076 no_effect YOL098C 2223 - TTTCTCATTGTTTCTATTCT R|747|T R|747|K M|746|I M|746|I SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 0.9710991053180816 Q12496 0.932735025882721 0.955805003643036 0.9553959965705872 0.9553959965705872 0.01533665880560875 0.3122900128364563 1.0 1.0 43.31915155014281 25.0 0.0 no 12669 chrXV_133679 32077 no_effect YOL098C 2140 - TTCAACAAATAATGGATCGG E|720|Q E|720|K V|719|L V|719|I SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 0.7623375089146858 Q12496 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.0 0.0 0.5455747246742249 0.5483537912368774 36.142064942108455 35.0 0.0 no 12670 chrXV_133720r 32078 no_effect YOL098C 2096 + AACTAACAGAAATCTCTATT T|700|S T|700|I N|701|K silent|AAC>AAT|N|701 SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 0.5824567995633976 Q12496 0.9491789937019348 0.9472420215606691 0.9439849853515624 0.4009309709072113 0.3979808986186981 0.9787876605987548 33.733547793173216 25.0 0.0 no 12671 chrXV_133828 32079 no_effect YOL098C 1991 - CATCAAAAACCATGTCAAAT D|670|H D|670|N SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 0.7220890601168709 Q12496 0.9486550092697144 0.956179976463318 0.015804501250386238 0.0426221564412117 35.449314486151145 30.0 0.0 no 12672 chrXV_133924 32080 no_effect YOL098C 1895 - GACAAGAACCCTTCAAACCT C|638|S C|638|Y SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 0.4925688714731255 Q12496 0.9421560168266296 0.9290120005607604 0.057205099612474435 0.5780392289161682 45.840051497333214 45.0 0.0 no 12673 chrXV_134025 32082 no_effect YOL098C 1794 - TCCTCATCAAGGATTTTCAT E|604|D silent|GAG>GAA|E|604 E|605|Q E|605|K SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 0.3820737474844621 Q12496 0.94931298494339 0.956179976463318 0.9475290179252625 45.70806151474329 35.0 0.0 no 12674 chrXV_134061 32083 no_effect YOL098C 1758 - TCGTCAAACATATTAAAATA E|593|Q E|593|K D|592|H D|592|N SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 0.8139305184093452 Q12496 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.1826479583978653 0.2342895418405533 0.13402874767780304 0.4896417558193207 30.70040647057755 20.0 0.0 no 12675 chrXV_134127 32084 no_effect YOL098C 1692 - TGCAGCTCTATAAATTGAGA silent|CTG>CTC|L|570 silent|CTG>CTA|L|570 E|569|D silent|GAG>GAA|E|569 SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 0.11747578081788262 Q12496 0.94931298494339 0.5733376145362854 41.11044967998726 35.0 0.0 no 12676 chrXV_134274 32086 no_effect YOL098C 1545 - ACAAATTCAACACTCTTTGA V|522|L V|522|I SDD3 Suppressor of Degenerative Death 1037.0 0 1 0 0 0.048948113353034936 Q12496 0.9539830088615416 0.9574310183525084 0.4171665906906128 1.0 37.845774683062636 30.0 0.0 no 12677 chrXV_134459 32087 no_effect YOL098C 1360 - CATCAAAGCGCTTGGTTTAG L|459|F silent|TTG>TTA|L|459 SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 0.3769304450689481 Q12496 0.9587849974632264 0.04450920596718788 45.385514764208715 45.0 0.0 no 12678 chrXV_134578r 32089 no_effect YOL098C 1238 + TTCATTAGTGTCTTCTCTCA S|414|* S|414|L SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 1.2150361576425044 Q12496 0.9298099875450134 0.4019047617912293 48.03109617712085 35.0 0.0 no 12679 chrXV_134609 32090 no_effect YOL098C 1210 - TTCATTACCATAAATATAGT E|410|Q E|410|K SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 0.3036703969114743 Q12496 0.956179976463318 0.9475290179252625 0.5301718711853027 0.8072048425674438 35.2029342350345 20.0 0.0 no 12680 chrXV_134720 32092 no_effect YOL098C 1099 - TCTTGATAAATCAATGGTAT R|373|T R|373|K SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 0.30379224019647155 Q12496 0.932735025882721 0.955805003643036 0.4785811305046082 0.8010458946228027 35.28880955520884 25.0 0.0 no 12681 chrXV_134744 32093 no_effect YOL098C 1075 - TTTCAAAATCTCCAGTACCT L|364|F silent|TTG>TTA|L|364 SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 0.8384427924527239 Q12496 0.9587849974632264 0.05790814384818078 44.55948244433319 35.0 0.0 no 12682 chrXV_134846 32095 no_effect YOL098C 973 - ACAATCAGTGGAATTTGCCA C|331|S C|331|Y D|330|H D|330|N SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 0.3312291958421931 Q12496 0.9421560168266296 0.9290120005607604 0.9486550092697144 0.956179976463318 0.16951720416545868 1.0 0.21276460587978366 0.5495801568031311 45.70430872307258 40.0 0.0 no 12683 chrXV_134905r 32096 no_effect YOL098C 911 + TTACTTTACTGACTCTGCAT Y|305|* silent|TAC>TAT|Y|305 SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 0.4567829281451529 Q12496 44.66693594707096 35.0 0.0 no 12684 chrXV_135239 32101 no_effect YOL098C 580 - TCTGATTTCGTCGTTGGTTA R|200|T R|200|K SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 0.20603911809446465 Q12496 0.932735025882721 0.955805003643036 0.14030782878398895 0.6141543388366699 48.25359882121603 40.0 0.0 no 12685 chrXV_135309r 32105 no_effect YOL098C 507 + CAGCGATTAATGTTTCCTGA R|171|G R|171|* SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 0.16445019011234568 Q12496 0.8994590044021606 0.0183100663125515 45.72083714323424 40.0 0.0 no 12686 chrXV_135342r 32106 no_effect YOL098C 474 + ACTCAGGGCTGGTACATTTC Q|160|E Q|160|* T|159|S T|159|I SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 -0.4019040630732419 Q12496 0.9590039849281312 0.9491789937019348 0.9472420215606691 0.08025302737951279 0.2371998876333237 0.02304462343454361 52.319473571746705 50.0 0.0 no 12687 chrXV_135353r 32107 no_effect YOL098C 463 + AAGCCATTGAAACTCAGGGC A|156|G A|156|V silent|GCC>GCG|A|156 silent|GCC>GCT|A|156 SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 0.2289810939772968 Q12496 0.9484469890594482 0.9504740238189696 1.0 0.02230880409479141 47.90673830934981 50.0 0.0 no 12688 chrXV_135405r 32109 no_effect YOL098C 411 + CACATCGACCCGGAAAATTT H|138|Q silent|CAC>CAT|H|138 I|139|M silent|ATC>ATT|I|139 SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 0.7822095299132765 Q12496 0.9588389992713928 0.9598389863967896 0.0 0.01307322084903717 44.62937422505451 45.0 0.0 no 12689 chrXV_135433r 32112 no_effect YOL098C 383 + AGACGAGGCTTGTTTAACTG D|129|E silent|GAC>GAT|D|129 SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 -0.4849114294606212 Q12496 0.9532920122146606 0.29571276903152466 44.79882458141981 45.0 0.0 no 12690 chrXV_135448r 32113 no_effect YOL098C 368 + ACATCCAACTTTAACAGACG H|124|D H|124|Y P|125|A P|125|S SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 0.3718059054442555 Q12496 0.9473130106925964 0.9489949941635132 0.9562489986419678 0.9498909711837769 0.26672419905662537 0.5018883943557739 0.0 0.0 41.31843133200175 40.0 0.0 no 12691 chrXV_135548 32116 no_effect YOL098C 271 - GTCGGTATCAGTCCAAGCAT D|97|H D|97|N SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 0.4645335657915802 Q12496 0.9486550092697144 0.956179976463318 0.0 0.0 53.169128538577816 50.0 0.0 no 12692 chrXV_135598 32117 no_effect YOL098C 221 - TGTCTAATAAACCTTTGTAT D|80|H D|80|N SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 0.14839508247794508 Q12496 0.9486550092697144 0.956179976463318 0.0 0.0 37.647682258762586 25.0 0.0 no 12693 chrXV_135609r 32118 no_effect YOL098C 207 + TCTAAATCTTACCCATACAA S|70|C S|70|F SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 -0.5429102028697053 Q12496 0.945252001285553 0.9294660091400146 0.0 0.0 40.38651908433695 30.0 0.0 no 12694 chrXV_135652r 32120 no_effect YOL098C 164 + TTCAGGTGCTCCGCATACCT S|56|* S|56|L SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 0.10117207385812173 Q12496 0.9298099875450134 0.006582507397979498 58.80450264957215 55.00000000000001 0.0 no 12695 chrXV_135669r 32121 no_effect YOL098C 147 + ACAGAATGTCTTAATGATTC T|50|R T|50|I SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 0.7880756262520128 Q12496 0.9476869702339172 0.9472420215606691 0.0 0.0 36.588677171628426 30.0 0.0 no 12696 chrXV_135699 32122 no_effect YOL098C 120 - GCAAAGTAACCGTGAACCAA A|47|P A|47|T SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 0.13288900895362735 Q12496 0.9573720097541808 0.9523990154266356 0.020345810800790787 0.020825719460844997 43.61344142392944 45.0 0.0 no 12697 chrXV_135715r 32124 no_effect YOL098C 101 + AAACCACAAAACCTCCCCAT N|35|K silent|AAC>AAT|N|35 H|36|D H|36|Y SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 0.4056160074056721 Q12496 0.9439849853515624 0.9473130106925964 0.9489949941635132 0.4659083485603333 0.4276595711708069 0.22893176972866056 48.17132469414031 45.0 0.0 no 12698 chrXV_135766 32125 no_effect YOL098C 53 - CCGAGATATATTTAGTTATA silent|TCG>TCC|S|24 silent|TCG>TCA|S|24 SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 0.4289948248205293 Q12496 37.45324511044828 25.0 0.0 no 12699 chrXV_135766r 32126 no_effect YOL098C 50 + CCATATAACTAAATATATCT H|18|D H|18|Y SDD3 Suppressor of Degenerative Death 1037.0 0 0 0 0 0.2742350930732665 Q12496 0.9473130106925964 0.9489949941635132 0.36594414710998535 0.16481715440750122 32.995906555088425 20.0 0.0 no 12700 chrXV_136849r 32127 essential YOL097C 954 + AACAAGTACGCATTCAGCGG N|319|K silent|AAC>AAT|N|319 WRS1 W (tryptophan) RS (tRNA synthetase) 432.0 0 1 0 0 0.12226847668808084 Q12109 0.9439849853515624 0.2394557446241379 -0.9175999760627748 46.37282656934741 50.0 0.0 no 12701 chrXV_137024r 32133 essential YOL097C 779 + TCCATATTTCAGAGTTTGTA P|261|R P|261|L P|261|A P|261|S WRS1 W (tryptophan) RS (tRNA synthetase) 432.0 0 0 0 0 0.35767832592058724 Q12109 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0012334160273894668 0.0016325248870998619 0.04862337186932564 0.007168409880250692 1.2541999816894531 1.478600025177002 1.8020000457763672 3.0107998847961426 43.920032674153106 30.0 0.0 no 12702 chrXV_137030 32134 essential YOL097C 776 - AAACTCTGAAATATGGATCT V|265|L V|265|I R|264|T R|264|K WRS1 W (tryptophan) RS (tRNA synthetase) 432.0 0 0 0 0 0.08911363041450722 Q12109 0.9539830088615416 0.9574310183525084 0.932735025882721 0.955805003643036 0.8345924019813538 0.07325265556573868 0.0043488615192472935 0.017642099410295486 -0.3616000115871429 -0.5982000231742859 0.6948000192642212 -0.16279999911785126 35.81743856825767 30.0 0.0 no 12703 chrXV_137086 32135 essential YOL097C 720 - TCAGGCAAGCCTAACACATT D|247|H D|247|N L|245|F silent|TTG>TTA|L|245 WRS1 W (tryptophan) RS (tRNA synthetase) 432.0 0 0 0 0 0.4248356862268231 Q12109 0.9486550092697144 0.956179976463318 0.9587849974632264 0.09721282869577408 0.3963898718357086 0.04516922682523728 1.1571999788284302 0.8758000135421753 4.438000202178955 2.122080087661743 48.3776977048438 45.0 0.0 no 12704 chrXV_137099 32138 essential YOL097C 707 - ACACATTAGGAAATGAGCTT V|242|L V|242|M silent|GTG>GTC|V|242 silent|GTG>GTA|V|242 WRS1 W (tryptophan) RS (tRNA synthetase) 432.0 0 0 0 0 -1.1081686872716308 Q12109 0.9539830088615416 0.9587630033493042 0.2863088250160217 0.08135567605495453 2.732599973678589 3.11299991607666 40.194544186939936 35.0 0.0 no 12705 chrXV_137184r 32139 essential YOL097C 619 + CCACTGCAAAGGCTGTTTTC T|208|S T|208|I silent|TCC>TCG|S|207 silent|TCC>TCT|S|207 WRS1 W (tryptophan) RS (tRNA synthetase) 432.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.5903975769039339 Q12109 0.9491789937019348 0.9472420215606691 0.15849162638187408 0.02180943824350834 0.8113999962806702 -0.5120000243186951 50.73843248307036 50.0 0.0 no 12706 chrXV_137305r 32141 essential YOL097C 498 + GCCAAGGATATCATTGCTGT silent|GCC>GCG|A|167 silent|GCC>GCT|A|167 A|167|G A|167|V WRS1 W (tryptophan) RS (tRNA synthetase) 432.0 0 0 0 1 0.2236781830924858 Q12109 0.9484469890594482 0.9504740238189696 0.0007674064254388213 0.2680931985378265 2.0550000667572017 1.14520001411438 50.201489083480794 45.0 0.0 no 12707 chrXV_137424 32143 essential YOL097C 382 - AAACACTTCCTGTAACCATT silent|GTG>GTC|V|133 silent|GTG>GTA|V|133 V|133|L V|133|M WRS1 W (tryptophan) RS (tRNA synthetase) 432.0 0 0 0 0 0.42023623807061816 Q12109 0.9539830088615416 0.9587630033493042 0.11313267797231676 0.057514835149049766 2.8371999263763428 1.0562000274658203 43.495622270547706 35.0 0.0 no 12708 chrXV_137470r 32145 essential YOL097C 333 + TCGAGCGATTCTATGCACTT S|112|W S|112|L S|113|R silent|AGC>AGT|S|113 WRS1 W (tryptophan) RS (tRNA synthetase) 432.0 0 0 0 0 -0.8423140621976665 Q12109 0.9288619756698608 0.9298099875450134 0.9417110085487366 0.0 0.0 0.001126934657804668 1.8552000522613523 0.7753999829292297 -0.4092000126838684 2.336019992828369 -0.6466599702835083 0.2101999968290329 48.70167005107919 45.0 0.0 no 12709 chrXV_137503r 32148 essential YOL097C 300 + AAACCATTTTTCCTATACAC P|102|A P|102|S P|102|R P|102|L WRS1 W (tryptophan) RS (tRNA synthetase) 432.0 0 1 0 0 -0.5835477430391478 Q12109 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.10229253768920897 0.052583251148462296 0.07864775508642198 0.11923304200172424 0.9678000211715698 1.2175999879837036 0.5415999889373779 0.8820000290870667 40.787797439235646 30.0 0.0 no 12710 chrXV_137615 32149 essential YOL097C 191 - TCACTTGCTTGAATCTCTTC V|70|L V|70|M silent|GTG>GTC|V|70 silent|GTG>GTA|V|70 WRS1 W (tryptophan) RS (tRNA synthetase) 432.0 0 0 0 0 0.9537983387638364 Q12109 0.9539830088615416 0.9587630033493042 1.0 0.0134358499199152 1.3043999671936035 1.0013999938964844 0.34220001101493835 0.4462000131607056 46.41938127149354 40.0 0.0 no 12711 chrXV_141837 32153 essential YOL094C 699 - AACATTTTCTTCACTATTAG M|239|I M|239|I RFC4 Replication Factor C 323.0 0 1 0 0 0.4100526555048825 P40339 0.9553959965705872 0.9553959965705872 0.3485311567783356 0.3485311567783356 2.337500095367432 2.337500095367432 36.87132841218437 25.0 0.0 no 12712 chrXV_141838 32154 essential YOL094C 698 - ACATTTTCTTCACTATTAGA M|239|I M|239|I RFC4 Replication Factor C 323.0 0 1 0 0 -0.2298244760969122 P40339 0.9553959965705872 0.9553959965705872 0.3485311567783356 0.3485311567783356 2.337500095367432 2.337500095367432 39.54175324521549 25.0 0.0 no 12713 chrXV_141958r 32158 essential YOL094C 575 + AGCAATCATTTTTACAGCGG A|193|G A|193|V I|194|M silent|ATC>ATT|I|194 RFC4 Replication Factor C 323.0 0 0 0 0 0.8967448292846223 P40339 0.9484469890594482 0.9504740238189696 0.9598389863967896 0.012111805379390715 0.006247001700103283 0.01558356359601021 1.826900005340576 5.08296012878418 1.8687200546264648 1.6095000505447388 2.69729995727539 44.609548612582905 40.0 0.0 no 12714 chrXV_142077 32160 essential YOL094C 459 - ATCGCACATCTACTTTGCAG silent|GCG>GCC|A|159 silent|GCG>GCA|A|159 A|159|P A|159|T RFC4 Replication Factor C 323.0 0 0 0 0 0.2423444811015591 P40339 0.9573720097541808 0.9523990154266356 0.00805969163775444 0.14247557520866394 0.9060400128364564 0.502780020236969 1.0077400207519531 0.5117800235748291 48.240263696189395 45.0 0.0 no 12715 chrXV_142139r 32161 essential YOL094C 394 + AGCTATATTCGAACTCTACA L|133|V silent|CTA>TTA|L|133 RFC4 Replication Factor C 323.0 0 0 0 0 0.1967837848335772 P40339 0.9512209892272948 0.5077788233757019 0.8170400261878967 0.700219988822937 0.3319000005722046 42.102689985207356 35.0 0.0 no 12716 chrXV_142224 32165 essential YOL094C 312 - ACGATTTTATGTTTCCCTGG V|111|L V|111|I RFC4 Replication Factor C 323.0 0 0 0 0 -0.1803362166442505 P40339 0.9539830088615416 0.9574310183525084 0.01684880442917347 0.509699285030365 -0.06923999637365341 0.7065200209617615 48.166143772166606 40.0 0.0 no 12717 chrXV_142330 32166 essential YOL094C 206 - AAACACCGTCAGCATAAGAG V|75|L V|75|I G|74|A G|74|D RFC4 Replication Factor C 323.0 0 1 0 0 -0.1878504400871276 P40339 0.9539830088615416 0.9574310183525084 0.9499930143356324 0.9446240067481996 0.04747938364744186 0.15431015193462372 1.0 0.026952244341373444 1.108919978141785 1.395799994468689 -1.171419978141785 4.813240051269531 42.71340254103461 45.0 0.0 no 12718 chrXV_142410r 32169 essential YOL094C 123 + ATGCCCCATATGATCATATC P|43|A P|43|S P|43|R P|43|L RFC4 Replication Factor C 323.0 0 0 0 0 -0.06614091073158301 P40339 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.01806829869747162 0.05854252725839615 0.0019627930596470837 0.0021979112643748517 1.889899969100952 1.6749999523162842 1.7746399641036987 1.8120800256729128 48.952386454724035 40.0 0.0 no 12719 chrXV_142437r 32170 essential YOL094C 96 + CTTCAGCAAATCGCTAAAGA Q|34|E Q|34|* Q|35|E Q|35|* RFC4 Replication Factor C 323.0 0 0 0 0 0.04112685560436727 P40339 0.9590039849281312 0.9590039849281312 0.3291749656200409 0.9987002611160278 0.7279199957847595 0.8517199754714966 41.2109691774462 40.0 0.0 no 12720 chrXV_142483 32171 essential YOL094C 53 - CGACTATATCAGATAAAACT V|24|L V|24|I RFC4 Replication Factor C 323.0 0 0 0 0 0.1745754037095536 P40339 0.9539830088615416 0.9574310183525084 0.0077485907822847375 0.005828443914651871 0.7673599720001221 0.1934400051832199 -0.1804800033569336 0.15622000396251678 34.470576234015034 30.0 0.0 no 12721 chrXV_181717 32174 essential YOL078W 35 + TCAGTTTCTACGAGTGTGTC Q|13|E Q|13|* AVO1 Adheres VOraciously (to TOR2) 1176.0 0 0 0 0 -0.3613575119628008 Q08236 0.9590039849281312 0.0 48.843148039641676 45.0 1.0 no 12722 chrXV_181861 32175 essential YOL078W 179 + ACCTGAACTAGAGTCTCCAC P|61|R P|61|L P|61|A P|61|S AVO1 Adheres VOraciously (to TOR2) 1176.0 0 1 0 0 -0.5050420574394454 Q08236 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.5445386171340942 0.2203107178211212 0.5614038109779358 0.8962090015411377 50.0874004934779 50.0 1.0 no 12723 chrXV_181880r 32178 essential YOL078W 201 - TCCATAAAATCCTTAGATAC M|73|I M|73|I E|74|Q E|74|K AVO1 Adheres VOraciously (to TOR2) 1176.0 0 0 0 0 0.0994389988216346 Q08236 0.9553959965705872 0.9553959965705872 0.956179976463318 0.9475290179252625 0.21088498830795288 0.21088498830795288 0.03866388648748398 0.0315232127904892 38.15584361320015 30.0 1.0 no 12724 chrXV_182173 32181 essential YOL078W 491 + CTCATATTTAAATAGTTCGA S|165|* S|165|L AVO1 Adheres VOraciously (to TOR2) 1176.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.5064042151489472 Q08236 0.9298099875450134 0.14585387706756592 35.645397774780925 25.0 1.0 no 12725 chrXV_182321 32182 essential YOL078W 639 + TCATCTACTTTGCATCCACC S|214|* S|214|L S|215|C S|215|F AVO1 Adheres VOraciously (to TOR2) 1176.0 0 0 0 0 0.2757970271592948 Q08236 0.9298099875450134 0.945252001285553 0.9294660091400146 0.2715190052986145 0.05633150041103362 0.06531353294849396 52.09259528562114 45.0 1.0 no 12726 chrXV_182220 32183 essential YOL078W 538 + GATCGTCGCTTCCTTTCGTG S|181|W S|181|L S|182|W S|182|L AVO1 Adheres VOraciously (to TOR2) 1176.0 0 0 0 0 0.5559356937718584 Q08236 0.9288619756698608 0.9298099875450134 0.9288619756698608 0.9298099875450134 0.0044825137592852116 0.025511182844638824 0.026683995500206947 0.2289581149816513 54.878068420261 55.00000000000001 1.0 no 12727 chrXV_182510 32185 essential YOL078W 828 + CCAGCCCACAAAGGCATCAA P|277|R P|277|L A|278|G A|278|V AVO1 Adheres VOraciously (to TOR2) 1176.0 0 0 0 0 -0.31166987715425754 Q08236 0.9432820081710817 0.9430609941482544 0.9484469890594482 0.9504740238189696 0.6695460081100464 0.3482637107372284 0.5581268072128296 0.2290377616882324 53.084659640787955 55.00000000000001 1.0 no 12728 chrXV_182515r 32187 essential YOL078W 836 - ACATGCCGTTGATGCCTTTG M|285|I M|285|I G|284|A G|284|D AVO1 Adheres VOraciously (to TOR2) 1176.0 0 1 0 0 0.9682144219455479 Q08236 0.9553959965705872 0.9553959965705872 0.9499930143356324 0.9446240067481996 0.8132910728454591 0.8132910728454591 0.15312698483467102 0.6128717660903931 53.10957860564821 50.0 1.0 no 12729 chrXV_182644 32189 essential YOL078W 962 + TCATTTCCCCACAAGTCAAA H|322|D H|322|Y F|323|L silent|TTC>TTT|F|323 AVO1 Adheres VOraciously (to TOR2) 1176.0 0 1 0 0 1.1885090826498446 Q08236 0.9473130106925964 0.9489949941635132 0.9387490153312684 0.22976981103420255 0.0518527552485466 0.09941361844539642 47.74137737616269 40.0 1.0 no 12730 chrXV_182724r 32190 essential YOL078W 1045 - ATCTCCATGTATACCTTTAT D|355|H D|355|N G|354|A G|354|E AVO1 Adheres VOraciously (to TOR2) 1176.0 0 1 0 0 0.9128390997140692 Q08236 0.9486550092697144 0.956179976463318 0.9499930143356324 0.9438679814338684 0.10321776568889618 0.6048282980918884 0.7794755697250366 0.8363301157951355 45.67005691142242 30.0 1.0 no 12731 chrXV_182757r 32192 essential YOL078W 1078 - ACTCACCGATCCGTTACCGC silent|GTG>GTC|V|365 silent|GTG>GTA|V|365 S|366|T S|366|N AVO1 Adheres VOraciously (to TOR2) 1176.0 0 0 1 Series([], Name: modification, dtype: object) 0 -0.09052715012812368 Q08236 0.9512869715690612 0.9536849856376648 0.5323460698127747 0.5878044962882996 56.6874082192461 60.0 1.0 no 12732 chrXV_182877r 32195 essential YOL078W 1198 - TACTGTTTTGTTTATGTTTG V|406|L V|406|I AVO1 Adheres VOraciously (to TOR2) 1176.0 0 1 0 0 0.5244658122445417 Q08236 0.9539830088615416 0.9574310183525084 0.7364897727966309 0.6750721931457521 39.37344293489457 25.0 1.0 no 12733 chrXV_182888 32196 essential YOL078W 1206 + AACAAAACAGTATCTGATTT N|403|K silent|AAC>AAT|N|403 AVO1 Adheres VOraciously (to TOR2) 1176.0 0 1 0 0 0.34612246289953824 Q08236 0.9439849853515624 0.4489332437515259 33.85513046590893 25.0 1.0 no 12734 chrXV_182912 32197 essential YOL078W 1230 + GGACATGAATCTACAAATGA H|412|D H|412|Y AVO1 Adheres VOraciously (to TOR2) 1176.0 0 1 0 0 -0.27119648066177104 Q08236 0.9473130106925964 0.9489949941635132 0.7201346755027771 0.9945122599601746 36.990155151682075 35.0 1.0 no 12735 chrXV_182920 32198 essential YOL078W 1238 + ATCTACAAATGATGGAACGG S|414|C S|414|F T|415|R T|415|I AVO1 Adheres VOraciously (to TOR2) 1176.0 1 Series([], Name: modification, dtype: object) 0 0 0 -2.7850367274854904 Q08236 0.945252001285553 0.9294660091400146 0.9476869702339172 0.9472420215606691 0.024418789893388748 0.012843505479395391 0.3921605348587036 0.1400892436504364 38.2416258031015 40.0 1.0 yes 12736 chrXV_182999 32199 essential YOL078W 1317 + AATCGTGACCGAATCACTCC R|441|G R|441|C AVO1 Adheres VOraciously (to TOR2) 1176.0 0 1 0 0 -0.8088495265684079 Q08236 0.8994590044021606 0.8926740288734436 0.37361037731170654 0.060998748987913125 47.90559851159418 50.0 1.0 no 12737 chrXV_183011 32200 essential YOL078W 1329 + ATCACTCCTGGCTCATCATA I|444|M silent|ATC>ATT|I|444 T|445|S T|445|I AVO1 Adheres VOraciously (to TOR2) 1176.0 0 1 0 0 0.3335054859482872 Q08236 0.9598389863967896 0.9491789937019348 0.9472420215606691 0.8590131402015686 0.06723029166460037 52.69650762267236 45.0 1.0 no 12738 chrXV_183012 32201 essential YOL078W 1330 + TCACTCCTGGCTCATCATAT T|445|S T|445|I I|444|M silent|ATC>ATT|I|444 AVO1 Adheres VOraciously (to TOR2) 1176.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.13897439538603826 Q08236 0.9491789937019348 0.9472420215606691 0.9598389863967896 0.8590131402015686 0.06723029166460037 52.69650762267243 45.0 1.0 no 12739 chrXV_183017r 32202 essential YOL078W 1338 - GACTTCCCATATGATGAGCC K|452|N silent|AAG>AAA|K|452 silent|GGG>GGC|G|451 silent|GGG>GGA|G|451 AVO1 Adheres VOraciously (to TOR2) 1176.0 0 1 0 0 -0.9003087961500678 Q08236 0.9355990290641784 0.013511389493942259 52.20407516156503 50.0 1.0 no 12740 chrXV_183093r 32204 essential YOL078W 1414 - AGACATTTCACCGCTCTCCA M|477|I M|477|I AVO1 Adheres VOraciously (to TOR2) 1176.0 0 0 0 0 0.2444779184967329 Q08236 0.9553959965705872 0.9553959965705872 0.29513126611709595 0.29513126611709595 54.87497920236842 50.0 1.0 no 12741 chrXV_183252 32207 essential YOL078W 1570 + CATCGCGACACCCAAAAGAA S|525|W S|525|L R|526|G R|526|* AVO1 Adheres VOraciously (to TOR2) 1176.0 0 0 0 0 0.578775801919355 Q08236 0.9288619756698608 0.9298099875450134 0.8994590044021606 0.021114595234394073 0.22688086330890656 0.090685673058033 45.11837653155203 50.0 1.0 no 12742 chrXV_183342 32210 essential YOL078W 1660 + GCTCGAATTTAACTTCAACA S|555|W S|555|L S|554|R silent|AGC>AGT|S|554 AVO1 Adheres VOraciously (to TOR2) 1176.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.5310395621663299 Q08236 0.9288619756698608 0.9298099875450134 0.9417110085487366 0.0054237511940300465 0.036290552467107766 0.32554560899734497 40.39261508254157 35.0 1.0 no 12743 chrXV_183365 32211 essential YOL078W 1683 + TCTCCTCTTTTACGAGGACA P|563|A P|563|S S|562|C S|562|F AVO1 Adheres VOraciously (to TOR2) 1176.0 0 1 0 0 -0.04430400335999085 Q08236 0.9562489986419678 0.9498909711837769 0.945252001285553 0.9294660091400146 0.5223017334938049 0.8866127133369446 0.04329222440719605 0.06487493962049484 50.11767589927729 45.0 1.0 no 12744 chrXV_183368r 32212 essential YOL078W 1689 - CTTCCATGTCCTCGTAAAAG G|569|A G|569|E G|569|R G|569|R AVO1 Adheres VOraciously (to TOR2) 1176.0 0 0 0 0 1.2555067271606726 Q08236 0.9499930143356324 0.9438679814338684 0.941340982913971 0.941340982913971 0.8879504799842834 1.0 0.5812482237815857 0.5812482237815857 46.19845222541562 45.0 1.0 no 12745 chrXV_183405r 32213 essential YOL078W 1726 - GGCTTTCATGTGTTCACTAC A|582|P A|582|T M|580|I M|580|I AVO1 Adheres VOraciously (to TOR2) 1176.0 0 0 0 0 0.2746679054894545 Q08236 0.9573720097541808 0.9523990154266356 0.9553959965705872 0.9553959965705872 0.20168036222457889 0.38753896951675415 0.4493574500083923 0.4493574500083923 50.14208726802292 45.0 1.0 no 12746 chrXV_183426r 32214 essential YOL078W 1747 - TACACTGTCAGAAACCTTTG V|589|L V|589|I S|588|T S|588|N AVO1 Adheres VOraciously (to TOR2) 1176.0 0 1 0 0 0.5261408824421219 Q08236 0.9539830088615416 0.9574310183525084 0.9512869715690612 0.9536849856376648 0.4796497821807861 0.31744593381881714 0.5271046757698059 0.4241945147514343 42.424875230797625 40.0 1.0 no 12747 chrXV_183435 32215 essential YOL078W 1753 + TTTCTGACAGTGTATTGCAT S|586|C S|586|F AVO1 Adheres VOraciously (to TOR2) 1176.0 0 1 0 0 -0.4665376575995842 Q08236 0.945252001285553 0.9294660091400146 0.0549558587372303 0.05814976990222931 45.32490824063427 35.0 1.0 no 12748 chrXV_183509r 32219 essential YOL078W 1830 - GAGCTTTTATGGACACTTGA S|616|T S|616|N AVO1 Adheres VOraciously (to TOR2) 1176.0 0 0 0 0 -0.08043572242177502 Q08236 0.9512869715690612 0.9536849856376648 1.0 0.4132845997810364 45.304188099271755 40.0 1.0 no 12749 chrXV_183519 32221 essential YOL078W 1837 + TCCATAAAAGCTCGAAAGAG H|614|D H|614|Y silent|GTC>GTG|V|613 silent|GTC>GTT|V|613 AVO1 Adheres VOraciously (to TOR2) 1176.0 0 0 0 0 0.3544410433347159 Q08236 0.9473130106925964 0.9489949941635132 0.09830491244792937 0.2949451506137848 38.25095940413701 40.0 1.0 no 12750 chrXV_183547r 32222 essential YOL078W 1868 - AATCGGTGGTTTTCTCAATA D|629|H D|629|N AVO1 Adheres VOraciously (to TOR2) 1176.0 0 0 0 0 0.2985061739411209 Q08236 0.9486550092697144 0.956179976463318 0.017395157366991043 0.2500058114528656 43.54990560647957 35.0 1.0 no 12751 chrXV_183591r 32224 essential YOL078W 1912 - GAACATATTCGATAACTGTG M|643|I M|643|I AVO1 Adheres VOraciously (to TOR2) 1176.0 0 0 0 0 -0.010588511987755013 Q08236 0.9553959965705872 0.9553959965705872 0.06378859281539917 0.06378859281539917 36.96217649946266 35.0 1.0 no 12752 chrXV_183584r 32225 essential YOL078W 1905 - TTCGATAACTGTGAGGCCTT silent|TCG>TCC|S|641 silent|TCG>TCA|S|641 AVO1 Adheres VOraciously (to TOR2) 1176.0 0 0 0 0 1.0112671865140352 Q08236 48.763599775944726 45.0 1.0 no 12753 chrXV_183782 32226 essential YOL078W 2100 + TCTACCATCTTCGAAGTTAT S|701|C S|701|F T|702|S T|702|I AVO1 Adheres VOraciously (to TOR2) 1176.0 0 0 0 0 0.3507619562458958 Q08236 0.945252001285553 0.9294660091400146 0.9491789937019348 0.9472420215606691 0.012152763083577156 0.005179729778319597 0.25370410084724426 0.036486290395259864 44.329318263514146 35.0 1.0 no 12754 chrXV_183839r 32227 essential YOL078W 2160 - CCATCTTCTTCAAAATTGTC G|727|R G|727|R D|726|H D|726|N AVO1 Adheres VOraciously (to TOR2) 1176.0 0 0 0 0 0.17779661583168982 Q08236 0.941340982913971 0.941340982913971 0.9486550092697144 0.956179976463318 0.009781576693058014 0.009781576693058014 0.0 0.0 42.00929918370775 35.0 1.0 no 12755 chrXV_184046 32229 essential YOL078W 2364 + ACACCTTTACCATTTGAAAC P|790|A P|790|S T|789|R T|789|I AVO1 Adheres VOraciously (to TOR2) 1176.0 0 0 0 0 -2.193079120115425 Q08236 0.9562489986419678 0.9498909711837769 0.9476869702339172 0.9472420215606691 0.25821852684021 0.05661797150969505 0.0 0.0 41.9933018191108 35.0 1.0 yes 12756 chrXV_184055r 32231 essential YOL078W 2376 - AGGCCCCCACCAGTTTCAAA G|798|A G|798|D G|798|R G|798|S AVO1 Adheres VOraciously (to TOR2) 1176.0 0 0 0 0 -0.6939077815441934 Q08236 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.5353855490684509 0.5612075328826904 0.366501659154892 0.6001271605491638 58.84572398206183 55.00000000000001 1.0 no 12757 chrXV_184075 32232 essential YOL078W 2393 + CCTAATGGATGCTTCTACTT L|799|V silent|CTA>TTA|L|799 AVO1 Adheres VOraciously (to TOR2) 1176.0 0 0 0 0 0.5832671009322692 Q08236 0.9512209892272948 0.4608480036258698 46.893975240491784 40.0 1.0 no 12758 chrXV_184157r 32234 essential YOL078W 2478 - TCGTCTTCATTACCTATAAT D|833|H D|833|N D|832|H D|832|N AVO1 Adheres VOraciously (to TOR2) 1176.0 0 0 0 0 -0.12753430307797087 Q08236 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.09857355803251266 0.4842052459716797 0.056443952023983 0.4425000250339508 42.51306859261223 30.0 1.0 no 12759 chrXV_184282 32236 essential YOL078W 2600 + CTCACATATAAACGATATTT S|868|* S|868|L H|869|D H|869|Y AVO1 Adheres VOraciously (to TOR2) 1176.0 0 0 0 0 -1.0915879171720089 Q08236 0.9298099875450134 0.9473130106925964 0.9489949941635132 0.01800074614584446 0.3627259731292725 0.06352277845144272 34.59566009032483 25.0 1.0 no 12760 chrXV_186054 32237 essential YOL077C 650 - TGACAGTCATAACAAACCTA V|223|L V|223|I BRX1 Xenopus laevis Brix (Biogenesis of Ribosomes in Xenopus) homolog 291.0 0 0 0 0 1.0675919215562828 Q08235 0.9539830088615416 0.9574310183525084 0.4188947677612305 0.4949746131896973 39.57860966864047 35.0 0.0 no 12761 chrXV_186077r 32238 essential YOL077C 624 + GACATATCATTAGTGGAAAT D|209|E silent|GAC>GAT|D|209 BRX1 Xenopus laevis Brix (Biogenesis of Ribosomes in Xenopus) homolog 291.0 0 0 0 0 0.6335336630008823 Q08235 0.9532920122146606 1.0 36.891713186034735 30.0 0.0 no 12762 chrXV_186263 32241 essential YOL077C 441 - TCCTTAATTAATTGGTAGTG K|153|N silent|AAG>AAA|K|153 E|154|Q E|154|K BRX1 Xenopus laevis Brix (Biogenesis of Ribosomes in Xenopus) homolog 291.0 0 0 0 0 0.0737962159738621 Q08235 0.9355990290641784 0.956179976463318 0.9475290179252625 0.004508334677666426 0.08290574699640274 0.07757984101772307 39.40893463247238 30.0 0.0 no 12763 chrXV_186264r 32243 essential YOL077C 437 + CCCACACTACCAATTAATTA P|147|R P|147|L P|147|A P|147|S BRX1 Xenopus laevis Brix (Biogenesis of Ribosomes in Xenopus) homolog 291.0 0 0 0 0 0.23898975846980725 Q08235 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.00957129057496786 0.007633053231984377 0.09436003863811493 0.0260093342512846 43.75627644456733 35.0 0.0 no 12764 chrXV_186424r 32244 essential YOL077C 277 + AACACCAAGATTTGTATCTA H|94|D H|94|Y H|94|Q silent|CAC>CAT|H|94 BRX1 Xenopus laevis Brix (Biogenesis of Ribosomes in Xenopus) homolog 291.0 0 0 0 0 0.12572899719973493 Q08235 0.9473130106925964 0.9489949941635132 0.9588389992713928 0.11537424474954605 0.09099692851305008 0.28468337655067444 39.670663667562046 30.0 0.0 no 12765 chrXV_186515 32245 essential YOL077C 189 - TCCTTTTTAGTATCCAATTT K|69|N silent|AAG>AAA|K|69 D|70|H D|70|N BRX1 Xenopus laevis Brix (Biogenesis of Ribosomes in Xenopus) homolog 291.0 0 0 0 0 -0.2007970111364233 Q08235 0.9355990290641784 0.9486550092697144 0.956179976463318 1.0 0.06453076004981995 0.5982967019081116 43.503651494652786 25.0 0.0 no 12766 chrXV_186605r 32247 essential YOL077C 96 + ACTCTTCTGATTTCGAGTAG L|34|V L|34|F T|33|S T|33|I BRX1 Xenopus laevis Brix (Biogenesis of Ribosomes in Xenopus) homolog 291.0 0 0 0 0 0.10845792134482844 Q08235 0.9512209892272948 0.9587849974632264 0.9491789937019348 0.9472420215606691 0.007571444381028414 0.007398829795420171 0.003343690885230899 0.1829628199338913 44.599983720184134 40.0 0.0 no 12767 chrXV_186681 32248 essential YOL077C 23 - TATCTTTGCTCTTTCCTGCG D|14|H D|14|N BRX1 Xenopus laevis Brix (Biogenesis of Ribosomes in Xenopus) homolog 291.0 0 0 0 0 -0.1440068023651461 Q08235 0.9486550092697144 0.956179976463318 0.1278768628835678 0.4731030166149139 52.512793196333924 45.0 0.0 no 12768 chrXV_187070r 32250 high_effect YOL076W 49 - TGCATAGCATTGTTTGAAGT A|23|P A|23|T MDM20 Mitochondrial Distribution and Morphology 796.0 0 0 0 0 -0.11104469350890167 Q12387 0.9573720097541808 0.9523990154266356 0.19200003147125244 0.337837815284729 44.203699943180936 35.0 1.0 no 12769 chrXV_187078 32251 high_effect YOL076W 54 + AAACAATGCTATGCAAAACT Q|20|E Q|20|* MDM20 Mitochondrial Distribution and Morphology 796.0 0 0 0 0 -0.8891097750522059 Q12387 0.9590039849281312 0.13243421912193298 35.34359442866736 30.0 1.0 no 12770 chrXV_187079 32252 high_effect YOL076W 55 + AACAATGCTATGCAAAACTG Q|20|E Q|20|* MDM20 Mitochondrial Distribution and Morphology 796.0 0 0 0 0 0.3595635066637156 Q12387 0.9590039849281312 0.13243421912193298 36.52489959013865 35.0 1.0 no 12771 chrXV_187120r 32253 high_effect YOL076W 99 - ATCTTGAAGTACAACGCATT K|39|N silent|AAG>AAA|K|39 MDM20 Mitochondrial Distribution and Morphology 796.0 0 1 0 0 0.41550358230624906 Q12387 0.9355990290641784 0.48073995113372797 41.27828322056757 35.0 1.0 no 12772 chrXV_187125 32255 high_effect YOL076W 101 + TGCGTTGTACTTCAAGATTT A|35|G A|35|V MDM20 Mitochondrial Distribution and Morphology 796.0 0 0 0 0 1.2654915848775967 Q12387 0.9484469890594482 0.9504740238189696 0.08388552814722061 0.030733546242117882 43.9347828466922 35.0 1.0 no 12773 chrXV_187151r 32256 high_effect YOL076W 130 - TGACTGCTTGAATTTAACAT Q|49|H silent|CAG>CAA|Q|49 K|48|N silent|AAG>AAA|K|48 MDM20 Mitochondrial Distribution and Morphology 796.0 0 0 0 0 0.44932153634570543 Q12387 0.9570760130882264 0.9355990290641784 0.34906095266342163 0.02673184871673584 38.55760971032851 30.0 1.0 no 12774 chrXV_187268 32261 high_effect YOL076W 244 + ACAACTTCTTCGTAGAGTTA H|82|Q silent|CAC>CAT|H|82 N|83|K silent|AAC>AAT|N|83 MDM20 Mitochondrial Distribution and Morphology 796.0 0 0 0 0 0.15021743472960758 Q12387 0.9588389992713928 0.9439849853515624 0.01791828311979771 1.0 42.733308001767675 35.0 1.0 no 12775 chrXV_187343 32263 high_effect YOL076W 319 + GCTACGAATTGTCTTATCAC S|107|R silent|AGC>AGT|S|107 Y|108|* silent|TAC>TAT|Y|108 MDM20 Mitochondrial Distribution and Morphology 796.0 0 0 0 0 0.4252031357921616 Q12387 0.9417110085487366 0.2942614555358887 43.530201826244145 40.0 1.0 no 12776 chrXV_187484 32264 high_effect YOL076W 460 + TCTCGATTTTAGCCGTATCA S|155|W S|155|L I|154|M silent|ATC>ATT|I|154 MDM20 Mitochondrial Distribution and Morphology 796.0 0 0 0 0 -0.33441803006012594 Q12387 0.9288619756698608 0.9298099875450134 0.9598389863967896 0.01372139435261488 0.09257954359054564 0.26950016617774963 48.70861959351043 40.0 1.0 no 12777 chrXV_187532 32265 high_effect YOL076W 508 + CCAAGAAAATTTTGCTCTCC silent|CCC>CCG|P|170 silent|CCC>CCT|P|170 MDM20 Mitochondrial Distribution and Morphology 796.0 0 0 0 0 1.0390894646391773 Q12387 43.52005157307252 40.0 1.0 no 12778 chrXV_187642r 32268 high_effect YOL076W 621 - TCCGAGATTTCTCTAGATTG silent|TCG>TCC|S|213 silent|TCG>TCA|S|213 E|214|Q E|214|K MDM20 Mitochondrial Distribution and Morphology 796.0 0 0 0 0 -0.4138850621790327 Q12387 0.956179976463318 0.9475290179252625 0.5238396525382996 0.8839851617813109 44.86467896811894 40.0 1.0 no 12779 chrXV_188008r 32270 high_effect YOL076W 987 - TTCAAATCGATTGAACAACA L|335|F silent|TTG>TTA|L|335 MDM20 Mitochondrial Distribution and Morphology 796.0 0 0 0 0 0.03547640794977033 Q12387 0.9587849974632264 0.0533989816904068 35.265230166153685 30.0 1.0 no 12780 chrXV_188020 32271 high_effect YOL076W 996 + ATCGATTTGAATCATTACAG I|333|M silent|ATC>ATT|I|333 MDM20 Mitochondrial Distribution and Morphology 796.0 0 0 0 0 -0.060652110891455134 Q12387 0.9598389863967896 0.04992866888642311 36.92329478298467 30.0 1.0 no 12781 chrXV_188112 32273 high_effect YOL076W 1088 + TCATTGTAATATTCTAGAAT H|364|D H|364|Y MDM20 Mitochondrial Distribution and Morphology 796.0 0 0 0 0 0.6884457711587254 Q12387 0.9473130106925964 0.9489949941635132 1.0 0.011617908254265785 33.78966118723076 20.0 1.0 no 12782 chrXV_188226 32277 high_effect YOL076W 1202 + ATTCTTATTAGAAATAGTCA F|402|L silent|TTC>TTT|F|402 MDM20 Mitochondrial Distribution and Morphology 796.0 0 0 0 0 1.7731255374674113 Q12387 0.9387490153312684 0.08625602722167969 33.948051668416554 20.0 1.0 no 12783 chrXV_188328r 32280 high_effect YOL076W 1307 - ACATAGTATCGAAGTTATGA M|442|I M|442|I MDM20 Mitochondrial Distribution and Morphology 796.0 0 0 0 0 -0.2279692012773777 Q12387 0.9553959965705872 0.9553959965705872 0.2297264933586121 0.2297264933586121 37.83116509428282 30.0 1.0 no 12784 chrXV_188609 32284 high_effect YOL076W 1585 + TACTAGGAATGCTCGAGATG L|530|V silent|CTA>TTA|L|530 MDM20 Mitochondrial Distribution and Morphology 796.0 0 0 0 0 0.8996667107991643 Q12387 0.9512209892272948 0.03800572454929352 42.7274951491944 45.0 1.0 no 12785 chrXV_188610 32285 high_effect YOL076W 1586 + ACTAGGAATGCTCGAGATGA L|530|V silent|CTA>TTA|L|530 MDM20 Mitochondrial Distribution and Morphology 796.0 0 0 0 0 0.7238844116751469 Q12387 0.9512209892272948 0.03800572454929352 44.444546072237934 45.0 1.0 no 12786 chrXV_188723 32286 high_effect YOL076W 1699 + TACAAAAATTACACGAAGAT Q|568|E Q|568|* MDM20 Mitochondrial Distribution and Morphology 796.0 0 0 0 0 0.3133343218435881 Q12387 0.9590039849281312 0.8273099064826965 30.741086979379414 25.0 1.0 no 12787 chrXV_198962 32287 essential YOL069W 20 + GTTCCCCATTTTGGATCTAC F|8|L silent|TTC>TTT|F|8 P|9|A P|9|S NUF2 NUclear Filament-containing protein 451.0 0 0 0 0 0.6160308377535226 P33895 0.0 0.0 0.0 53.05123485006497 45.0 1.0 no 12788 chrXV_199079 32290 essential YOL069W 137 + ACAAATCATCGAGAACTTCA Q|47|E Q|47|* I|48|M silent|ATC>ATT|I|48 NUF2 NUclear Filament-containing protein 451.0 0 0 0 0 -0.09149688428317017 P33895 0.3059139549732208 0.0 38.64766013795304 35.0 1.0 no 12789 chrXV_199436 32298 essential YOL069W 494 + GCAACAGCTAAAGCAATACG Q|166|E Q|166|* Q|167|E Q|167|* NUF2 NUclear Filament-containing protein 451.0 0 0 0 0 0.8877090490616386 P33895 0.7926054000854492 0.26054701209068304 41.35499889778822 45.0 1.0 no 12790 chrXV_199446 32299 essential YOL069W 504 + AAGCAATACGAGGACGTAGA Q|170|E Q|170|* NUF2 NUclear Filament-containing protein 451.0 0 0 0 0 0.20277687734121613 P33895 0.979232668876648 42.311617138774245 45.0 1.0 no 12791 chrXV_199816r 32302 essential YOL069W 877 - ATCATAGAGCTCACTAATTA D|299|H D|299|N NUF2 NUclear Filament-containing protein 451.0 0 0 0 0 0.3072879898697429 P33895 0.06954871118068695 0.23744283616542816 39.80397971822372 30.0 1.0 no 12792 chrXV_203125 32305 essential YOL066C 1327 - ACACTTACCAGCTTCCTTAA K|448|N silent|AAG>AAA|K|448 C|449|S C|449|Y RIB2 RIBoflavin biosynthesis 591.0 0 0 0 0 -0.07941986242554629 Q12362 0.9355990290641784 0.9421560168266296 0.9290120005607604 0.1448732316493988 0.30390504002571106 0.06060299649834632 49.127479359180825 40.0 0.0 no 12793 chrXV_203142 32306 essential YOL066C 1310 - TAACGGCCATTTCCATATAT V|443|L V|443|I A|442|P A|442|T RIB2 RIBoflavin biosynthesis 591.0 0 0 0 0 0.4628672108574031 Q12362 0.9539830088615416 0.9574310183525084 0.9573720097541808 0.9523990154266356 0.6252517700195312 0.6963850855827332 0.05943505465984345 0.014401298947632313 45.500615159491815 35.0 0.0 no 12794 chrXV_203148r 32307 essential YOL066C 1301 + ACATCGCCGATATATGGAAA H|435|D H|435|Y R|436|G R|436|C RIB2 RIBoflavin biosynthesis 591.0 0 0 0 0 0.2154647970465809 Q12362 0.9473130106925964 0.9489949941635132 0.8994590044021606 0.8926740288734436 0.5265819430351257 0.20590105652809146 0.1916651427745819 0.021418249234557152 42.81005122151237 40.0 0.0 no 12795 chrXV_203254r 32310 essential YOL066C 1195 + ACCTCTGGCTGCATGCCTTC L|400|V L|400|F D|399|E silent|GAC>GAT|D|399 RIB2 RIBoflavin biosynthesis 591.0 0 0 0 0 0.055021018598674185 Q12362 0.9512209892272948 0.9587849974632264 0.9532920122146606 0.07985527813434601 0.02358881384134293 0.8103689551353455 62.0005583208764 60.0 0.0 no 12796 chrXV_203291r 32311 essential YOL066C 1158 + GCTGAAATGTACACAGATCC A|387|G A|387|V RIB2 RIBoflavin biosynthesis 591.0 0 0 0 0 0.5222395504234859 Q12362 0.9484469890594482 0.9504740238189696 0.5172616243362427 0.4339537024497986 44.43548003177699 45.0 0.0 no 12797 chrXV_203396r 32316 essential YOL066C 1053 + GTTCTGAAACTAGACGCTAT L|353|V silent|CTG>TTG|L|353 RIB2 RIBoflavin biosynthesis 591.0 0 0 0 0 -1.7209673852019296 Q12362 0.9512209892272948 0.2839185297489166 42.59626238860966 40.0 0.0 no 12798 chrXV_203438 32317 essential YOL066C 1014 - AGTCCACCGCGGCCCAAATC G|344|A G|344|E G|344|R G|344|R RIB2 RIBoflavin biosynthesis 591.0 0 0 0 0 -0.2769810140251061 Q12362 0.9499930143356324 0.9438679814338684 0.941340982913971 0.941340982913971 0.2355169802904129 0.1913585215806961 0.03255191445350647 0.03255191445350647 59.42608923471079 65.0 0.0 no 12799 chrXV_203462r 32320 essential YOL066C 987 + TACTCGAACCCAGATATCTG Y|330|* silent|TAC>TAT|Y|330 S|331|W S|331|L RIB2 RIBoflavin biosynthesis 591.0 0 0 0 0 -0.5943430713140934 Q12362 0.9288619756698608 0.9298099875450134 0.0038212654180824757 0.015117043629288672 45.728102591402596 45.0 0.0 no 12800 chrXV_203463r 32321 essential YOL066C 986 + ATACTCGAACCCAGATATCT Y|330|* silent|TAC>TAT|Y|330 S|331|W S|331|L RIB2 RIBoflavin biosynthesis 591.0 0 0 0 0 -2.399980617332604 Q12362 0.9288619756698608 0.9298099875450134 0.0038212654180824757 0.015117043629288672 45.73095247494172 40.0 0.0 yes 12801 chrXV_203469 32322 essential YOL066C 983 - TATCTGGGTTCGAGTATATA D|334|H D|334|N RIB2 RIBoflavin biosynthesis 591.0 0 0 0 0 -0.968965118566235 Q12362 0.9486550092697144 0.956179976463318 0.11565346270799635 0.4769644439220429 43.33137642418637 35.0 0.0 no 12802 chrXV_203651 32324 essential YOL066C 801 - ACAGCGTTTAGTGCAACTTT V|274|L V|274|I A|273|P A|273|T RIB2 RIBoflavin biosynthesis 591.0 0 0 0 0 0.42103344616693 Q12362 0.9539830088615416 0.9574310183525084 0.9573720097541808 0.9523990154266356 0.004680446814745665 0.04918888583779335 0.2020835429430008 0.3871616721153259 47.26046475427478 40.0 0.0 no 12803 chrXV_203652 32325 essential YOL066C 800 - CAGCGTTTAGTGCAACTTTA A|273|P A|273|T RIB2 RIBoflavin biosynthesis 591.0 0 0 0 0 0.6174921800039684 Q12362 0.9573720097541808 0.9523990154266356 0.2020835429430008 0.3871616721153259 46.24470885250332 40.0 0.0 no 12804 chrXV_203696 32326 essential YOL066C 756 - TCTACCTCTACTATACCTAT D|259|H D|259|N V|258|L V|258|I RIB2 RIBoflavin biosynthesis 591.0 0 0 0 0 0.3402467748187825 Q12362 0.9486550092697144 0.956179976463318 0.9539830088615416 0.9574310183525084 0.02633398398756981 0.15952879190444946 0.013629565946757792 0.058031439781188965 46.58992357286246 35.0 0.0 no 12805 chrXV_203697 32327 essential YOL066C 755 - CTACCTCTACTATACCTATA V|258|L V|258|I E|257|D silent|GAG>GAA|E|257 RIB2 RIBoflavin biosynthesis 591.0 0 0 0 0 -0.06076734762149065 Q12362 0.9539830088615416 0.9574310183525084 0.94931298494339 0.013629565946757792 0.058031439781188965 0.2596561312675476 45.01098367806475 35.0 0.0 no 12806 chrXV_203700r 32328 essential YOL066C 749 + GTTCCCTATAGGTATAGTAG F|251|L silent|TTC>TTT|F|251 P|252|A P|252|S RIB2 RIBoflavin biosynthesis 591.0 0 0 0 0 0.1797266639019225 Q12362 0.9387490153312684 0.9562489986419678 0.9498909711837769 0.0036863337736576796 0.013056580908596516 0.02277727611362934 47.609595433194436 40.0 0.0 no 12807 chrXV_203754 32330 essential YOL066C 698 - TGACTTCCCTCGCTTTCATT V|239|L V|239|I E|238|Q E|238|K RIB2 RIBoflavin biosynthesis 591.0 0 0 0 0 0.2435894751594277 Q12362 0.9539830088615416 0.9574310183525084 0.956179976463318 0.9475290179252625 0.1065627932548523 0.20459409058094025 0.6065649390220642 0.8934955596923828 54.17315878565347 45.0 0.0 no 12808 chrXV_203780 32331 essential YOL066C 672 - CCCATTCTATCTGCACCTAA M|230|I M|230|I G|231|R G|231|R RIB2 RIBoflavin biosynthesis 591.0 0 0 0 0 0.07720655875989332 Q12362 0.9553959965705872 0.9553959965705872 0.941340982913971 0.941340982913971 0.32313841581344604 0.32313841581344604 0.5358979701995851 0.5358979701995851 52.2304308645376 45.0 0.0 no 12809 chrXV_203781r 32333 essential YOL066C 668 + TCCATTAGGTGCAGATAGAA P|224|R P|224|L P|224|A P|224|S RIB2 RIBoflavin biosynthesis 591.0 0 0 0 0 -1.1595982049915945 Q12362 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.4271478056907654 0.3157753646373749 1.0 0.6539340019226074 45.493126507282575 40.0 0.0 no 12810 chrXV_203834 32336 essential YOL066C 618 - GGCTTGTCTAGTCTATTACA K|212|N silent|AAG>AAA|K|212 RIB2 RIBoflavin biosynthesis 591.0 0 1 0 0 0.2977831903891109 Q12362 0.9355990290641784 0.003061410505324602 48.86204237498396 40.0 0.0 no 12811 chrXV_203878 32337 essential YOL066C 574 - TCTTTCTAGCATTTTTGTAA R|198|T R|198|K E|197|Q E|197|K RIB2 RIBoflavin biosynthesis 591.0 0 0 0 0 0.2454839551253075 Q12362 0.932735025882721 0.955805003643036 0.956179976463318 0.9475290179252625 0.11586187779903412 1.0 0.6747604608535767 1.0 41.090683047840685 25.0 0.0 no 12812 chrXV_203972 32340 essential YOL066C 480 - TCTTCAAACACAATATCTAT D|167|H D|167|N E|166|Q E|166|K RIB2 RIBoflavin biosynthesis 591.0 0 0 0 0 0.9885332941570876 Q12362 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.005793388932943344 0.1766536980867386 0.10779161006212233 0.12384174019098282 35.53382349317616 25.0 0.0 no 12813 chrXV_203987 32341 essential YOL066C 465 - TCTATTGGTTTAGATGTGAC D|162|H D|162|N RIB2 RIBoflavin biosynthesis 591.0 0 0 0 0 1.2210842620401399 Q12362 0.9486550092697144 0.956179976463318 0.10990584641695024 0.3089692294597626 41.85430916042481 35.0 0.0 no 12814 chrXV_204192r 32344 essential YOL066C 257 + CACTTATAAAACTTTCTGTA T|87|S T|87|I RIB2 RIBoflavin biosynthesis 591.0 0 1 0 0 -0.07255555786551182 Q12362 0.9491789937019348 0.9472420215606691 0.12581877410411835 0.032212257385253906 35.2156114342439 25.0 0.0 no 12815 chrXV_204235r 32345 essential YOL066C 214 + TGACAATTGATGGACCCTTA T|73|R T|73|I RIB2 RIBoflavin biosynthesis 591.0 0 0 0 0 -0.4116653014053481 Q12362 0.9476869702339172 0.9472420215606691 0.17517893016338348 0.3172927796840668 45.339772364136074 40.0 0.0 no 12816 chrXV_204248 32346 essential YOL066C 204 - TCAATTGTCACTTCATAATC D|75|H D|75|N RIB2 RIBoflavin biosynthesis 591.0 0 0 0 0 1.2818754036960562 Q12362 0.9486550092697144 0.956179976463318 0.005505419801920652 0.05368731543421745 38.64027674399216 30.0 0.0 no 12817 chrXV_204322 32347 essential YOL066C 130 - TCCACTCGCATCTTTGACTT G|50|R G|50|R G|50|A G|50|E RIB2 RIBoflavin biosynthesis 591.0 0 0 0 0 -0.3323782514852736 Q12362 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.5042887330055237 0.5042887330055237 0.6691411733627319 1.0 51.89141150139136 45.0 0.0 no 12818 chrXV_234996 32350 high_effect YOL051W 56 + GAACGTCAACGGGTTGCTTC N|20|K silent|AAC>AAT|N|20 silent|GTC>GTG|V|21 silent|GTC>GTT|V|21 GAL11 GALactose metabolism 1081.0 0 0 0 0 0.01841815857277473 P19659 0.9439849853515624 0.2982240319252014 0.9815000295639038 49.63435732618552 55.00000000000001 1.0 no 12819 chrXV_235055r 32353 high_effect YOL051W 118 - TCTTATCTTATCAGCAGTGT R|46|T R|46|K K|44|N silent|AAG>AAA|K|44 GAL11 GALactose metabolism 1081.0 0 0 0 0 0.8522811221895326 P19659 0.932735025882721 0.955805003643036 0.9355990290641784 0.012779793702065943 1.0 0.0 0.8326799869537354 -0.3750199973583221 0.792739987373352 46.935474660218404 35.0 1.0 no 12820 chrXV_235169 32354 high_effect YOL051W 229 + TGCGCAACACGTACAATACG R|78|G R|78|C silent|CGC>CGG|R|78 silent|CGC>CGT|R|78 GAL11 GALactose metabolism 1081.0 0 1 0 0 0.5166921487481534 P19659 0.8994590044021606 0.8926740288734436 0.2441018521785736 0.026004284620285038 0.5730000138282776 0.9117799997329712 44.35087923225178 50.0 1.0 no 12821 chrXV_235468r 32359 high_effect YOL051W 531 - TGCAGTAATTGTTTGGGAAT silent|CTG>CTC|L|183 silent|CTG>CTA|L|183 GAL11 GALactose metabolism 1081.0 0 0 0 0 -0.2866407449974358 P19659 42.46040995694421 35.0 1.0 no 12822 chrXV_235474r 32360 high_effect YOL051W 537 - ATTCTTTGCAGTAATTGTTT R|185|T R|185|K GAL11 GALactose metabolism 1081.0 0 0 0 0 0.5159098530069213 P19659 0.932735025882721 0.955805003643036 0.020313743501901627 0.6349153518676758 0.4382399916648865 -0.5523399710655212 41.38327536243906 25.0 1.0 no 12823 chrXV_235511r 32362 high_effect YOL051W 574 - CTGCTGCCAGGTGTTGATAT Q|197|H silent|CAG>CAA|Q|197 W|196|C W|196|* GAL11 GALactose metabolism 1081.0 0 0 0 0 -0.01211133263773584 P19659 0.9570760130882264 0.8858469724655151 0.03790149465203285 0.0 0.5308600068092346 4.894480228424072 54.060267415093854 50.0 1.0 no 12824 chrXV_235557 32363 high_effect YOL051W 617 + GCTATTGACACCTCAGGATA L|207|V silent|CTA>TTA|L|207 GAL11 GALactose metabolism 1081.0 0 0 0 0 -0.04035799168972942 P19659 0.9512209892272948 0.35497036576271057 1.169219970703125 48.945127555777155 45.0 1.0 no 12825 chrXV_235551 32364 high_effect YOL051W 611 + ACAAAAGCTATTGACACCTC Q|205|E Q|205|* GAL11 GALactose metabolism 1081.0 0 0 0 0 0.6503046137234278 P19659 0.9590039849281312 0.0353568010032177 0.0294599998742342 41.87510194517154 40.0 1.0 no 12826 chrXV_235567r 32365 high_effect YOL051W 630 - TTCGCAGCTTCCATATCCTG silent|GCG>GCC|A|216 silent|GCG>GCA|A|216 A|216|P A|216|T GAL11 GALactose metabolism 1081.0 0 0 0 0 -0.053513281068116085 P19659 0.9573720097541808 0.9523990154266356 0.023985788226127625 0.2417374849319458 4.1875200271606445 -0.5891199707984924 54.63565636369929 50.0 1.0 no 12827 chrXV_235678 32368 high_effect YOL051W 738 + AACAACGGCCTCCCCCAAAA N|247|K silent|AAC>AAT|N|247 N|248|K silent|AAC>AAT|N|248 GAL11 GALactose metabolism 1081.0 0 0 0 0 0.7906233301153394 P19659 0.9439849853515624 0.9439849853515624 0.9215863943099976 0.9343807101249696 52.57735684609924 55.00000000000001 1.0 no 12828 chrXV_235827 32369 high_effect YOL051W 887 + TAACCAAATCTTTTCTCCAG N|297|K silent|AAC>AAT|N|297 Q|298|E Q|298|* GAL11 GALactose metabolism 1081.0 0 1 0 0 0.5306230938461196 P19659 0.9439849853515624 0.9590039849281312 0.016037972643971443 0.1909794956445694 42.39945060405007 35.0 1.0 no 12829 chrXV_235905 32370 high_effect YOL051W 965 + ACAATTGGGTAGTACGATGA Q|323|E Q|323|* GAL11 GALactose metabolism 1081.0 0 0 0 0 -0.1470986946101951 P19659 0.9590039849281312 0.07023564726114273 42.64674860355228 40.0 1.0 no 12830 chrXV_235974r 32371 high_effect YOL051W 1037 - TCAAAGCTTGGATTTTTCTC L|352|F silent|TTG>TTA|L|352 A|351|P A|351|T GAL11 GALactose metabolism 1081.0 0 0 0 0 -0.28153292959155063 P19659 0.9587849974632264 0.9573720097541808 0.9523990154266356 0.103889599442482 0.2478760182857513 0.8318459987640381 42.636479161780755 35.0 1.0 no 12831 chrXV_236011 32374 high_effect YOL051W 1071 + AACAATAACGCTAACAACAA N|358|K silent|AAC>AAT|N|358 GAL11 GALactose metabolism 1081.0 0 0 0 0 -0.7195876479065433 P19659 0.9439849853515624 0.7288542985916138 33.579997795084466 30.0 1.0 no 12832 chrXV_236120r 32375 high_effect YOL051W 1183 - AGCATTAGGTGTAGCAGAAG A|401|P A|401|T GAL11 GALactose metabolism 1081.0 0 0 0 0 0.06834108714687698 P19659 0.9573720097541808 0.9523990154266356 0.3135839104652405 0.6629154086112976 45.821446801834725 45.0 1.0 no 12833 chrXV_236403r 32382 high_effect YOL051W 1466 - GCTGAGCTTGTTGTGGTTGT Q|495|H silent|CAG>CAA|Q|495 A|494|P A|494|T GAL11 GALactose metabolism 1081.0 0 0 0 0 -0.8841764854982052 P19659 0.9570760130882264 0.9573720097541808 0.9523990154266356 0.14622554183006287 0.28077971935272217 0.2940727472305298 55.9158677278279 50.0 1.0 no 12834 chrXV_236425 32383 high_effect YOL051W 1485 + CAACAACCTAACCCACTACA Q|497|E Q|497|* P|498|A P|498|S GAL11 GALactose metabolism 1081.0 0 0 0 0 -0.7218835386014284 P19659 0.9590039849281312 0.9562489986419678 0.9498909711837769 0.2351978421211243 0.3440543115139008 0.3470190763473511 46.00736041562232 45.0 1.0 no 12835 chrXV_236426 32385 high_effect YOL051W 1486 + AACAACCTAACCCACTACAT Q|497|E Q|497|* P|498|A P|498|S GAL11 GALactose metabolism 1081.0 0 0 0 0 -0.5792953167226149 P19659 0.9590039849281312 0.9562489986419678 0.9498909711837769 0.2351978421211243 0.3440543115139008 0.3470190763473511 44.85575301763197 40.0 1.0 no 12836 chrXV_236455r 32386 high_effect YOL051W 1518 - ACTTCGACATCCTTTGCAGT V|513|L V|513|I E|512|Q E|512|K GAL11 GALactose metabolism 1081.0 0 0 0 0 0.7152457082516983 P19659 0.9539830088615416 0.9574310183525084 0.956179976463318 0.9475290179252625 0.1518237590789795 0.21997611224651334 0.09922537207603456 0.1104837879538536 51.742333871675385 45.0 1.0 no 12837 chrXV_236498 32387 high_effect YOL051W 1558 + ATGCTTCTAAGACCAACCTA A|521|G A|521|V S|522|C S|522|F GAL11 GALactose metabolism 1081.0 0 0 0 0 0.6867583814433771 P19659 0.9484469890594482 0.9504740238189696 0.945252001285553 0.9294660091400146 0.016326233744621273 1.0 0.06298154592514038 0.043638281524181366 46.50080640585418 40.0 1.0 no 12838 chrXV_237111 32395 high_effect YOL051W 2156 + CCATAAAAATACCTCTAGCA H|720|D H|720|Y GAL11 GALactose metabolism 1081.0 0 0 0 0 -0.06552934780734672 P19659 40.955650823474635 35.0 1.0 no 12839 chrXV_237122r 32396 high_effect YOL051W 2170 - GTTCAAAAAATCCATGCTAG L|729|F silent|TTG>TTA|L|729 GAL11 GALactose metabolism 1081.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.13641469839628395 P19659 38.31383166812157 35.0 1.0 no 12840 chrXV_253282r 32405 essential YOL040C 273 + TCCGTCGTCGGTATCTACAA silent|TCC>TCG|S|92 silent|TCC>TCT|S|92 S|92|C S|92|F RPS15 Ribosomal Protein of the Small subunit 142.0 0 0 0 0 0.4056726301687055 Q01855 0.06580076366662979 0.12708133459091187 0.1157199963927269 5.010660171508789 51.35044604001485 50.0 0.0 no 12841 chrXV_253297 32406 essential YOL040C 261 - ACGACGGAACCGATCATTTC V|94|L V|94|I V|93|L V|93|I RPS15 Ribosomal Protein of the Small subunit 142.0 0 0 0 0 -0.06473400467071566 Q01855 0.0671018734574318 0.421285092830658 0.17287327349185946 0.8438813090324402 1.8860599994659424 -0.07199999690055847 -0.1803400069475174 -0.3304800093173981 46.192695108094036 50.0 0.0 no 12842 chrXV_253419 32412 essential YOL040C 139 - TGGCTTGGAAGTCATACCAC K|52|N silent|AAG>AAA|K|52 RPS15 Ribosomal Protein of the Small subunit 142.0 1 Series([], Name: modification, dtype: object) 0 0 0 -1.9098775870110325 Q01855 0.07110292464494705 0.40046000480651855 49.83575370705023 50.0 0.0 no 12843 chrXV_253444 32413 essential YOL040C 114 - AATCTTCTTCTAACTCTAGC R|44|T R|44|K R|43|T R|43|K RPS15 Ribosomal Protein of the Small subunit 142.0 0 0 0 0 0.041782405888794096 Q01855 0.25320860743522644 0.4646525979042053 0.033696822822093964 0.02924404852092266 1.3691999912261963 -0.2293999940156937 -0.26767998933792114 -0.2809399962425232 42.66943541591309 35.0 0.0 no 12844 chrXV_253445 32414 essential YOL040C 113 - ATCTTCTTCTAACTCTAGCT R|44|T R|44|K R|43|T R|43|K RPS15 Ribosomal Protein of the Small subunit 142.0 0 0 0 0 -1.1928383606019384 Q01855 0.25320860743522644 0.4646525979042053 0.033696822822093964 0.02924404852092266 1.3691999912261963 -0.2293999940156937 -0.26767998933792114 -0.2809399962425232 46.27032574385487 35.0 0.0 no 12845 chrXV_253446 32415 essential YOL040C 112 - TCTTCTTCTAACTCTAGCTG R|44|T R|44|K R|43|T R|43|K RPS15 Ribosomal Protein of the Small subunit 142.0 0 0 0 0 -2.080719633559044 Q01855 0.25320860743522644 0.4646525979042053 0.033696822822093964 0.02924404852092266 1.3691999912261963 -0.2293999940156937 -0.26767998933792114 -0.2809399962425232 46.26449254022378 40.0 0.0 yes 12846 chrXV_253470 32417 essential YOL040C 88 - CAACTTGACGAAATCTTCAG K|35|N silent|AAG>AAA|K|35 RPS15 Ribosomal Protein of the Small subunit 142.0 1 Series([], Name: modification, dtype: object) 0 0 0 -1.2658421450237758 Q01855 0.15973998606204987 0.2633799910545349 38.50736589874299 40.0 0.0 no 12847 chrXV_255591 32426 essential YOL038W 254 + TATCGAGAAGGCTAGAGTGG I|86|M silent|ATC>ATT|I|86 PRE6 PRoteinase yscE 254.0 0 1 0 0 -0.5401862686903327 P40303 0.007352293003350495 -0.16444000601768494 45.48230869027742 50.0 1.0 no 12848 chrXV_255615r 32429 essential YOL038W 281 - CCAACGTTAGTCTGTGACTT L|100|F silent|TTG>TTA|L|100 silent|ACG>ACC|T|99 silent|ACG>ACA|T|99 PRE6 PRoteinase yscE 254.0 0 0 0 0 1.5135712040849134 P40303 0.4360624849796295 0.034219998866319656 0.23583999276161194 48.41644208114246 45.0 1.0 no 12849 chrXV_255703 32433 essential YOL038W 366 + TCAGGAGGTGTTAGACCATT S|123|* S|123|L PRE6 PRoteinase yscE 254.0 0 0 0 0 -0.16923950973328694 P40303 0.06645074486732483 -0.4207600057125092 49.85291547061348 45.0 1.0 no 12850 chrXV_255718r 32434 essential YOL038W 384 - ATCAGCGTCGACACACCAAA silent|CTG>CTC|L|134 silent|CTG>CTA|L|134 silent|ACG>ACC|T|133 silent|ACG>ACA|T|133 PRE6 PRoteinase yscE 254.0 0 0 0 0 0.2163520291817171 P40303 48.1231660586526 50.0 1.0 no 12851 chrXV_260019 32444 essential YOL034W 96 + GACTTGTCTTCCTTCCAACC D|33|E silent|GAC>GAT|D|33 0 0 0 0 -0.13827161852120326 Q08204 0.9532920122146606 0.3511306047439575 54.47775241436762 50.0 1.0 no 12852 chrXV_260106r 32446 essential YOL034W 186 - CCAATGATCATATTTAAAGA G|69|R G|69|R 0 0 0 0 -2.3837184478293927 Q08204 0.941340982913971 0.941340982913971 0.0 0.0 34.77754286815588 25.0 1.0 yes 12853 chrXV_260154 32448 essential YOL034W 231 + TTCGTATGCGCAGTGTGTTT F|78|L silent|TTC>TTT|F|78 0 0 0 0 0.1470586924194049 Q08204 0.9387490153312684 0.2135233581066132 51.902886534108006 45.0 1.0 no 12854 chrXV_260190r 32452 essential YOL034W 270 - TTACTCCTACCAATATACTC S|96|T S|96|N R|95|S silent|AGG>AGA|R|95 0 0 0 0 -0.10352318014728012 Q08204 0.9512869715690612 0.9536849856376648 0.9087679982185364 0.2505244016647339 0.07760930806398393 0.0 43.526753967888745 35.0 1.0 no 12855 chrXV_260387r 32455 essential YOL034W 467 - TAACTACACTCTCAGATACC V|162|L V|162|I V|161|L V|161|I 0 0 0 0 0.4345945370062225 Q08204 0.9539830088615416 0.9574310183525084 0.9539830088615416 0.9574310183525084 0.09166951477527617 0.3134787380695343 0.7513388395309448 0.4586242735385895 42.99013978496294 40.0 1.0 no 12856 chrXV_260528 32456 essential YOL034W 605 + GTCAATCGATGCAAGCTTAT S|203|* S|203|L I|204|M silent|ATC>ATT|I|204 0 0 0 0 0.1339800529284158 Q08204 0.9298099875450134 0.9598389863967896 0.019687656313180923 0.028718696907162663 44.609548612583076 40.0 1.0 no 12857 chrXV_260537 32457 essential YOL034W 614 + TGCAAGCTTATTGGATGTGT A|206|G A|206|V S|207|R silent|AGC>AGT|S|207 0 0 0 0 -0.4815842299211844 Q08204 0.9484469890594482 0.9504740238189696 0.9417110085487366 0.49561715126037603 0.3915379643440247 0.1295788288116455 46.86319544051179 40.0 1.0 no 12858 chrXV_260681 32458 essential YOL034W 758 + ACGAGATTTTCAAAATAAGA R|254|G R|254|* 0 0 0 0 0.7901591411566997 Q08204 0.8994590044021606 0.1635599434375763 32.363477462719004 25.0 1.0 no 12859 chrXV_260804 32461 essential YOL034W 881 + GAACTTAAGGGCTATACTGA N|295|K silent|AAC>AAT|N|295 0 0 0 0 -0.3574501607274585 Q08204 0.9439849853515624 0.9148243069648744 42.09812530447528 40.0 1.0 no 12860 chrXV_260835r 32462 essential YOL034W 915 - GTCTTCTTAGTATTTGCAAA K|311|N silent|AAG>AAA|K|311 K|310|N silent|AAG>AAA|K|310 0 0 0 0 0.7189371569248606 Q08204 0.9355990290641784 0.9355990290641784 0.5054689049720764 0.3744442760944367 0.3749400079250336 1.279919981956482 2.736654043197632 41.63100308871395 30.0 1.0 no 12861 chrXV_261037r 32465 essential YOL034W 1117 - ATCTTCCTTTGTACTAATAA D|379|H D|379|N E|378|Q E|378|K 0 0 0 0 0.17561400109862615 Q08204 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.05371442437171936 0.32938534021377563 0.6274060606956482 0.895255446434021 39.50759627950685 25.0 1.0 no 12862 chrXV_261099r 32467 essential YOL034W 1179 - TCTTCAAATACGCTTTTCTC D|400|H D|400|N E|399|Q E|399|K 0 0 0 0 0.3596675019262716 Q08204 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.0532214529812336 0.3774440288543701 0.1650743931531906 0.21971724927425385 42.69882907050288 35.0 1.0 no 12863 chrXV_261181r 32468 essential YOL034W 1261 - GTTCGCCTTCGCATCAATTT silent|GCG>GCC|A|426 silent|GCG>GCA|A|426 A|426|P A|426|T 0 0 0 0 -0.3374676538362119 Q08204 0.9573720097541808 0.9523990154266356 0.16628053784370422 0.41487371921539307 52.008651958679884 45.0 1.0 no 12864 chrXV_261299r 32471 essential YOL034W 1379 - CACGGACCTCCTTTAAATCC R|466|P R|466|H V|465|L V|465|I 0 0 0 0 -0.6064336648752471 Q08204 0.9099509716033936 0.9570810198783876 0.9539830088615416 0.9574310183525084 0.01486183702945709 0.016346802935004234 0.7254384756088257 0.2255620062351227 49.80867833823828 50.0 1.0 no 12865 chrXV_261317r 32472 essential YOL034W 1397 - TAACCATCAACACAGCATCA V|472|L V|472|I M|471|I M|471|I 0 0 0 0 0.6128164006001661 Q08204 0.9539830088615416 0.9574310183525084 0.9553959965705872 0.9553959965705872 1.0 0.8395751714706421 0.12252137809991835 0.12252137809991835 44.375701473779486 40.0 1.0 no 12866 chrXV_261397r 32474 essential YOL034W 1477 - TGCAGCAAATTGAGCGTTAA A|499|P A|499|T A|498|P A|498|T 0 0 0 0 0.7329422726343865 Q08204 0.9573720097541808 0.9523990154266356 0.9573720097541808 0.9523990154266356 0.3976729512214661 0.3474791347980499 0.0 0.0 43.36357577342324 40.0 1.0 no 12867 chrXV_261416 32475 essential YOL034W 1493 + TGCATATTTAGCACAATGTG A|499|G A|499|V 0 0 0 0 0.2871542586617147 Q08204 0.9484469890594482 0.9504740238189696 0.4503226578235626 0.1665300726890564 41.37904869420163 35.0 1.0 no 12868 chrXV_261603 32482 essential YOL034W 1680 + TATCTATCCGATTTTATTAC L|562|V silent|CTA>TTA|L|562 0 0 0 0 0.4333438443846965 Q08204 0.9512209892272948 0.0 38.588836171566015 25.0 1.0 no 12869 chrXV_261622r 32483 essential YOL034W 1702 - TTTCATAACCCTCTTATCAC M|573|I M|573|I 0 0 0 0 -0.05682796498581141 Q08204 0.9553959965705872 0.9553959965705872 0.8748774528503418 0.8748774528503418 45.1718925759161 35.0 1.0 no 12870 chrXV_261659 32484 essential YOL034W 1736 + TAGCAAAATTCATACTATAC S|580|R silent|AGC>AGT|S|580 0 0 0 0 0.4103532661087205 Q08204 0.9417110085487366 0.6158880591392517 33.219853578062725 25.0 1.0 no 12871 chrXV_261670 32485 essential YOL034W 1747 + ATACTATACCGGTATCAAGA T|584|S T|584|I 0 0 0 0 0.05661737295431887 Q08204 0.9491789937019348 0.9472420215606691 0.4809368550777435 0.2344459295272827 41.858586098404096 35.0 1.0 no 12872 chrXV_261678r 32486 essential YOL034W 1758 - GTCAATTCCCTTCTTGATAC L|592|F silent|TTG>TTA|L|592 0 0 0 0 0.02450233388528289 Q08204 0.9587849974632264 0.18586140871047974 47.765044218394394 40.0 1.0 no 12873 chrXV_261702r 32487 essential YOL034W 1782 - ATCAACTTCTTTATCTGAGC L|600|F silent|TTG>TTA|L|600 K|599|N silent|AAG>AAA|K|599 0 0 0 0 0.7556303586990584 Q08204 0.9587849974632264 0.9355990290641784 0.0 0.5517760515213013 42.92096084007136 35.0 1.0 no 12874 chrXV_262277 32490 essential YOL034W 2354 + TCAATTTGAAGCCCAAAATA Q|786|E Q|786|* 0 0 0 0 0.1528843108417242 Q08204 0.9590039849281312 0.2810784876346588 0.4119400084018707 1.2381139993667605 38.600987064165786 30.0 1.0 no 12875 chrXV_262289r 32491 essential YOL034W 2369 - TCATAGAAACATCCATATTT M|796|I M|796|I 0 0 0 0 0.4226395789618107 Q08204 0.9553959965705872 0.9553959965705872 0.4836514294147492 0.4836514294147492 0.35589998960494995 0.35589998960494995 1.9701340198516848 1.9701340198516848 37.32272436432737 25.0 1.0 no 12876 chrXV_262358r 32492 essential YOL034W 2438 - ACTTTTTCTTGTCTTCATAT K|819|N silent|AAG>AAA|K|819 0 0 0 0 0.6278818626895261 Q08204 0.9355990290641784 0.6627295017242432 42.75001267440132 25.0 1.0 no 12877 chrXV_274098 32494 essential YOL026C 236 - CCTTATACCCCTTGTTTCTA K|85|N silent|AAG>AAA|K|85 MIM1 Mitochondrial IMport 113.0 0 0 0 0 0.413979134651556 Q08176 0.9355990290641784 0.019349547103047367 53.30216395666203 40.0 0.0 no 12878 chrXV_274175 32498 essential YOL026C 159 - AGCATCATGCCGTTGAGGAA M|59|I M|59|I M|58|I M|58|I MIM1 Mitochondrial IMport 113.0 0 0 0 0 -1.0563718080714024 Q08176 0.9553959965705872 0.9553959965705872 0.9553959965705872 0.9553959965705872 0.0 0.0 0.19008499383926392 0.19008499383926392 51.202409594945145 50.0 0.0 no 12879 chrXV_274184r 32499 essential YOL026C 147 + CTACTTTTGCCCTTCCTCAA L|51|V L|51|F MIM1 Mitochondrial IMport 113.0 0 0 0 0 -0.07629933102739833 Q08176 0.9512209892272948 0.9587849974632264 1.0 0.2436196655035019 54.19698407430286 45.0 0.0 no 12880 chrXV_278123r 32505 high_effect YOL023W 70 - AAGCAAATGAGGTATCGGTA L|29|F silent|TTG>TTA|L|29 IFM1 Initiation Factor of Mitochondria 676.0 0 0 0 0 0.09328423836091787 P25038 0.4655904173851013 42.00102728971899 40.0 1.0 no 12881 chrXV_278466r 32511 high_effect YOL023W 413 - CTCTTTTGGTTAATAATTTT R|144|T R|144|K IFM1 Initiation Factor of Mitochondria 676.0 0 0 0 0 0.3686472775984863 P25038 0.0029287578072398897 0.056448373943567276 36.34256210928658 20.0 1.0 no 12882 chrXV_278467r 32512 high_effect YOL023W 414 - GCTCTTTTGGTTAATAATTT R|144|T R|144|K A|145|P A|145|T IFM1 Initiation Factor of Mitochondria 676.0 0 0 0 0 0.3205186854842241 P25038 0.0029287578072398897 0.056448373943567276 1.0 0.005223665852099657 39.723124730364596 25.0 1.0 no 12883 chrXV_278491r 32513 high_effect YOL023W 438 - TGGCCCATTATAGTTACCAC G|152|A G|152|D G|152|R G|152|S IFM1 Initiation Factor of Mitochondria 676.0 0 0 0 0 0.3385647603853977 P25038 0.0 0.0 0.0 0.0 51.65822060029189 45.0 1.0 no 12884 chrXV_278531 32514 high_effect YOL023W 475 + CCACTATCATAGACTATCTA T|160|S T|160|I silent|ACC>ACG|T|159 silent|ACC>ACT|T|159 IFM1 Initiation Factor of Mitochondria 676.0 0 0 0 0 -0.029383135516717663 P25038 0.054146725684404366 0.0015174309955909848 43.02793883172262 35.0 1.0 no 12885 chrXV_278547 32516 high_effect YOL023W 491 + TCTAAGGAAATCTTCTGTTG L|165|V silent|CTA>TTA|L|165 IFM1 Initiation Factor of Mitochondria 676.0 0 0 0 0 0.6543061647265375 P25038 0.007081527728587389 39.148054685708985 35.0 1.0 no 12886 chrXV_278606r 32517 high_effect YOL023W 553 - CTTCGGAGCTGTTATTTGAA silent|CCG>CCC|P|190 silent|CCG>CCA|P|190 IFM1 Initiation Factor of Mitochondria 676.0 0 0 0 0 -0.651600739984172 P25038 45.0823823172683 40.0 1.0 no 12887 chrXV_278641 32518 high_effect YOL023W 585 + ATCACATTTTTAGACACCCC I|196|M silent|ATC>ATT|I|196 T|197|R T|197|I IFM1 Initiation Factor of Mitochondria 676.0 0 0 0 0 -0.4788900746285088 P25038 0.005496603436768055 0.0018886774778366087 0.002706218278035521 48.67297319996857 40.0 1.0 no 12888 chrXV_278672r 32521 high_effect YOL023W 619 - TCTTTCTCTCATTTTCAAAA R|213|T R|213|K E|212|Q E|212|K IFM1 Initiation Factor of Mitochondria 676.0 0 0 0 0 0.7121763220552729 P25038 0.0 0.0 1.0 0.20707601308822632 38.845473687965296 25.0 1.0 no 12889 chrXV_278706 32522 high_effect YOL023W 650 + TACTGATATTATTGTTTTGG T|218|S T|218|I IFM1 Initiation Factor of Mitochondria 676.0 0 0 0 0 0.7802003935267026 P25038 0.0 0.0 37.017245983449186 25.0 1.0 no 12890 chrXV_278935r 32523 high_effect YOL023W 882 - TCACCAGTTTTGGCACTTAT G|300|A G|300|D E|301|Q E|301|K IFM1 Initiation Factor of Mitochondria 676.0 0 0 0 0 -0.2677227320561384 P25038 0.0 0.0 0.5625231862068176 1.0 50.00525439444198 40.0 1.0 no 12891 chrXV_278967r 32524 high_effect YOL023W 914 - GGACTATTGATTCCTCTAAA V|311|L V|311|I IFM1 Initiation Factor of Mitochondria 676.0 0 0 0 0 0.15939509070482 P25038 0.323564887046814 0.38895028829574585 42.15899521851958 35.0 1.0 no 12892 chrXV_278988r 32526 high_effect YOL023W 935 - TATCCATTACTTCACTTAAT D|318|H D|318|N M|317|I M|317|I IFM1 Initiation Factor of Mitochondria 676.0 0 0 0 0 0.6089097066505568 P25038 0.0016191821778193116 0.004042910877615213 0.044708840548992164 0.044708840548992164 39.800303018637074 25.0 1.0 no 12893 chrXV_279207 32528 high_effect YOL023W 1151 + AACACCATCATATGCTACAG T|385|R T|385|I P|386|A P|386|S IFM1 Initiation Factor of Mitochondria 676.0 0 0 0 0 -0.3207180970008482 P25038 0.2802132070064545 0.1337648779153824 0.0 0.0 43.56775166400581 40.0 1.0 no 12894 chrXV_279514 32533 high_effect YOL023W 1458 + TCAGAAAGCATTTCCTCTCT S|487|* S|487|L IFM1 Initiation Factor of Mitochondria 676.0 0 0 0 0 1.281422333316943 P25038 0.7294797301292419 47.632236557413314 40.0 1.0 no 12895 chrXV_279567 32534 high_effect YOL023W 1511 + TTCTTCTGTTGGTATACCTA S|505|C S|505|F S|506|C S|506|F IFM1 Initiation Factor of Mitochondria 676.0 0 0 0 0 -0.8116060343834453 P25038 0.02764370292425156 0.13686633110046387 0.0210664626210928 0.010331191122531893 47.72967450833573 35.0 1.0 no 12896 chrXV_279489 32535 high_effect YOL023W 1433 + TGTCTCTGGCTCAGCAGAAG silent|GTC>GTG|V|479 silent|GTC>GTT|V|479 S|480|C S|480|F IFM1 Initiation Factor of Mitochondria 676.0 0 0 0 0 -0.5548997216118973 P25038 0.17730936408042908 0.7571396231651306 53.00322536670598 55.00000000000001 1.0 no 12897 chrXV_280583 32536 essential YOL022C 896 - CAACCACTTCTTGGAATTTT V|305|L V|305|I silent|GTG>GTC|V|304 silent|GTG>GTA|V|304 TSR4 Twenty S rRNA accumulation 408.0 0 0 0 0 0.4718979514607278 P25040 0.9629039764404296 0.9705730080604552 0.038295939564704895 0.22406919300556186 43.1315420934971 35.0 0.0 no 12898 chrXV_280853r 32538 essential YOL022C 623 + TGCTACCGTTTCTGCAAAGA A|209|G A|209|V T|210|S T|210|I TSR4 Twenty S rRNA accumulation 408.0 0 1 0 0 -0.13325672176247844 P25040 0.9672009944915771 0.9664270281791688 0.9665899872779846 0.9646379947662354 0.12973147630691528 0.09526001662015916 0.7860656976699829 0.3707782328128815 48.51760525109421 45.0 0.0 no 12899 chrXV_280946 32539 essential YOL022C 533 - TAGCATTTGCACCGCCAAAT A|184|P A|184|T TSR4 Twenty S rRNA accumulation 408.0 0 0 0 0 0.0014624724731018837 P25040 0.96628999710083 0.9576590061187744 0.2453073859214783 0.4964387118816376 49.886018043734964 45.0 0.0 no 12900 chrXV_280960r 32540 essential YOL022C 516 + GCTTTTTCAAGCAACCCATT A|173|G A|173|V TSR4 Twenty S rRNA accumulation 408.0 0 0 0 0 0.2995872925870541 P25040 0.9672009944915771 0.9664270281791688 0.714171290397644 0.17651546001434326 49.52541942227879 40.0 0.0 no 12901 chrXV_281129 32541 essential YOL022C 350 - TCCTTTGACATTCGGTACAC R|123|T R|123|K R|123|S silent|AGG>AGA|R|123 TSR4 Twenty S rRNA accumulation 408.0 0 0 0 0 0.2950917669927566 P25040 0.955632984638214 0.9748079776763916 0.9386019706726074 0.11992879211902617 0.7471024990081787 0.11261357367038727 48.40182467955822 45.0 0.0 no 12902 chrXV_281130r 32542 essential YOL022C 346 + TCCTGTGTACCGAATGTCAA L|117|V silent|CTG>TTG|L|117 F|116|L silent|TTC>TTT|F|116 TSR4 Twenty S rRNA accumulation 408.0 0 0 0 0 0.6554012441565703 P25040 0.9703750014305116 0.9584370255470276 0.6523104310035706 0.16280439496040344 48.67974772784794 45.0 0.0 no 12903 chrXV_281226 32543 essential YOL022C 253 - ACTCATCTGCTCATCATCTA M|90|I M|90|I S|91|T S|91|N TSR4 Twenty S rRNA accumulation 408.0 0 0 0 0 0.1137119576309947 P25040 0.9756749868392944 0.9756749868392944 0.9248650074005128 0.9289150238037108 0.1174936667084694 0.1174936667084694 49.26868944496914 40.0 0.0 no 12904 chrXV_281299 32544 essential YOL022C 180 - CCACATTTCAATAGTTCAGC C|66|S C|66|Y G|67|R G|67|S TSR4 Twenty S rRNA accumulation 408.0 0 0 0 0 -2.2523823691833664 P25040 0.9846540093421936 0.9674050211906432 0.9563270211219788 0.9761779904365541 0.0 0.0 0.17801611125469208 0.4952309131622314 45.76048655424871 40.0 0.0 yes 12905 chrXV_281435 32546 essential YOL022C 44 - CCGGTTTACTAGAATACGAA silent|CCG>CCC|P|21 silent|CCG>CCA|P|21 TSR4 Twenty S rRNA accumulation 408.0 0 0 0 0 1.1020286304462346 P25040 41.77039376361103 40.0 0.0 no 12906 chrXV_281435r 32547 essential YOL022C 41 + CCATTCGTATTCTAGTAAAC H|15|D H|15|Y S|16|W S|16|L TSR4 Twenty S rRNA accumulation 408.0 0 1 0 0 -0.024638287526904414 P25040 0.9762660264968872 0.9764170050621032 0.9502170085906982 0.9589700102806092 0.29661163687705994 1.0 0.1852990686893463 0.6814999580383301 40.84100765999517 35.0 0.0 no 12907 chrXV_283179r 32549 essential YOL021C 2225 + ATACGATGCCTTCCCTCAAA Y|743|* silent|TAC>TAT|Y|743 DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 -0.8019773049512325 Q08162 50.292620922882115 45.0 0.0 no 12908 chrXV_283310 32551 essential YOL021C 2097 - TCCATATGGACCTTAACCTC M|705|I M|705|I D|706|H D|706|N DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 0.12894753377453608 Q08162 0.43616536259651184 0.43616536259651184 0.015111401677131653 0.1287945806980133 49.617540452902794 45.0 0.0 no 12909 chrXV_283311r 32552 essential YOL021C 2093 + TCCTGAGGTTAAGGTCCATA P|699|R P|699|L P|699|A P|699|S DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 1 0 0 -0.3758689952496409 Q08162 0.0 0.0 0.0 0.0 51.028334828689204 45.0 0.0 no 12910 chrXV_283410 32556 essential YOL021C 1997 - CCATCGTTAATTCATCATTT M|672|I M|672|I silent|ACG>ACC|T|671 silent|ACG>ACA|T|671 DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 0.7538017265497523 Q08162 0.2139135450124741 0.2139135450124741 42.70738491673121 30.0 0.0 no 12911 chrXV_283542r 32558 essential YOL021C 1862 + ATTCGCATTCTCTGTCATTT F|622|L silent|TTC>TTT|F|622 A|623|G A|623|V DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 0.2519214526253669 Q08162 0.6159809231758118 0.0 0.0 48.04513450436207 35.0 0.0 no 12912 chrXV_283659 32560 essential YOL021C 1748 - TTGCAGCACCTTCCGCATCC A|589|P A|589|T A|588|P A|588|T DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 0.8188221284383548 Q08162 0.28564539551734924 0.598068118095398 0.026275429874658585 0.14670757949352264 61.13111825641226 60.0 0.0 no 12913 chrXV_283660 32561 essential YOL021C 1747 - TGCAGCACCTTCCGCATCCA A|589|P A|589|T A|588|P A|588|T DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 -1.0789982766989836 Q08162 0.28564539551734924 0.598068118095398 0.026275429874658585 0.14670757949352264 61.9334642128722 60.0 0.0 no 12914 chrXV_283727 32564 essential YOL021C 1680 - CCAACTTCCCAATTACCGTT G|567|R G|567|S V|566|L V|566|I DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 -4.117652889837677 Q08162 0.0 0.0 0.0447603277862072 0.06235846132040024 51.067467670267604 45.0 0.0 yes 12915 chrXV_283775 32566 essential YOL021C 1632 - TCAATATCAACACATCCTGG D|551|H D|551|N DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 -2.5708497543087274 Q08162 0.0 0.0 42.84496028385877 40.0 0.0 yes 12916 chrXV_283868 32569 essential YOL021C 1539 - TCAGGATCGTCCAGTTTTGT E|520|Q E|520|K DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 0.23756541037173745 Q08162 0.5187573432922363 0.44201400876045227 52.4673338667169 45.0 0.0 no 12917 chrXV_283894 32571 essential YOL021C 1513 - CTTCCAATCGTGGCCTTCTG W|510|C W|510|* W|510|S W|510|* DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 -0.7944589979385743 Q08162 0.0 0.0 55.182310363152844 55.00000000000001 0.0 no 12918 chrXV_283957 32572 essential YOL021C 1450 - AACATCATGCTCCAACAATA V|490|L V|490|I D|489|H D|489|N DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 0.2389762212671248 Q08162 0.02130761556327343 0.1785932034254074 0.0030582488980144267 0.008805779740214348 41.733160932985136 35.0 0.0 no 12919 chrXV_283995 32574 essential YOL021C 1412 - GAGCAGATTCAATTGTACCG A|477|P A|477|T DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 1.210367377199908 Q08162 0.02686825208365917 0.11711663752794264 45.480227425122564 45.0 0.0 no 12920 chrXV_284033r 32575 essential YOL021C 1371 + ACCACTCATAAATACCCATT silent|ACC>ACG|T|458 silent|ACC>ACT|T|458 T|458|S T|458|I DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 0.0959084765875486 Q08162 0.6160738468170166 0.3875036835670471 44.90663216880085 35.0 0.0 no 12921 chrXV_284083r 32576 essential YOL021C 1321 + CTGCTGAATTATTGGATAAG A|442|G A|442|V DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 -0.2438980712840281 Q08162 0.3684503436088562 0.2991988062858581 37.97101018741364 35.0 0.0 no 12922 chrXV_284165 32577 essential YOL021C 1242 - TTCTGTGTACTACTGCTTTG Q|420|H silent|CAG>CAA|Q|420 DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 0.36703670238263786 Q08162 0.1049780249595642 46.91492111159954 40.0 0.0 no 12923 chrXV_284259r 32578 essential YOL021C 1145 + ATCGAAAAAAATTCAGCCCA S|383|W S|383|L DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 0.7092232286008278 Q08162 0.016040382906794548 0.2772418856620789 39.6893374452805 35.0 0.0 no 12924 chrXV_284371 32584 essential YOL021C 1036 - GTCATCGCCAGCCTCAATAT D|352|H D|352|N D|351|H D|351|N DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 -1.1758336911350424 Q08162 0.09222612529993056 0.36868378520011896 0.06748965382575989 0.2539879381656647 54.45985580836162 50.0 0.0 no 12925 chrXV_284372 32585 essential YOL021C 1035 - TCATCGCCAGCCTCAATATC D|352|H D|352|N D|351|H D|351|N DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 -1.3281099852784684 Q08162 0.09222612529993056 0.36868378520011896 0.06748965382575989 0.2539879381656647 52.93402913124889 50.0 0.0 no 12926 chrXV_284382r 32587 essential YOL021C 1022 + TAACGATAACCCCGATATTG N|342|K silent|AAC>AAT|N|342 DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 0.728273570123653 Q08162 0.07104764133691788 42.46217144337561 40.0 0.0 no 12927 chrXV_284445r 32589 essential YOL021C 959 + GCTACCTCAATCAGAATGGA L|321|V silent|CTA>TTA|L|321 P|322|A P|322|S DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 -0.005353887413484748 Q08162 0.01661599613726139 0.02616916596889496 0.01701125130057335 46.61680963812961 45.0 0.0 no 12928 chrXV_284449r 32590 essential YOL021C 955 + AACTGCTACCTCAATCAGAA L|320|V silent|CTG>TTG|L|320 L|321|V silent|CTA>TTA|L|321 DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 -0.27883215543791634 Q08162 0.5444090962409973 0.01661599613726139 43.84252726298405 40.0 0.0 no 12929 chrXV_284518 32593 essential YOL021C 889 - CCCAACAATTAACACTGGTT G|303|R G|303|R G|303|A G|303|E DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 0.4437973787087468 Q08162 0.0 0.0 0.0 0.0 44.347354306758064 40.0 0.0 no 12930 chrXV_284518r 32594 essential YOL021C 886 + CCAAACCAGTGTTAATTGTT silent|TCC>TCG|S|296 silent|TCC>TCT|S|296 P|298|A P|298|S DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 -0.12194278589958113 Q08162 0.14361180365085602 0.04883305728435517 43.3266351590413 35.0 0.0 no 12931 chrXV_284519r 32595 essential YOL021C 885 + TCCAAACCAGTGTTAATTGT silent|TCC>TCG|S|296 silent|TCC>TCT|S|296 S|296|C S|296|F DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 0.5872489463514347 Q08162 0.037546809762716286 0.03520757332444191 44.00852357862272 35.0 0.0 no 12932 chrXV_284564r 32596 essential YOL021C 840 + TCAGAGTACAACTTTCTAGA S|281|* S|281|L DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 -0.5734502701400088 Q08162 0.0073659559711813935 41.174421925943314 35.0 0.0 no 12933 chrXV_284729 32599 essential YOL021C 678 - TCTCTGATGTCGTCTGCATT R|232|T R|232|K D|233|H D|233|N DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 -0.0252499144399079 Q08162 0.3166618049144745 0.40855705738067627 0.0 0.0 51.80456843962105 45.0 0.0 no 12934 chrXV_284875 32600 essential YOL021C 532 - GTGCTCACTATACCATTGAC E|183|D silent|GAG>GAA|E|183 E|183|Q E|183|K DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 -0.43775588891876616 Q08162 0.5825557112693787 0.5327114462852478 0.8074370026588441 48.27554495771994 45.0 0.0 no 12935 chrXV_285026 32602 essential YOL021C 381 - GTTCTTAATCTCGTGTACAC R|133|T R|133|K DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 -0.2589561419101739 Q08162 0.20143693685531616 1.0 44.71668751467945 40.0 0.0 no 12936 chrXV_285054 32603 essential YOL021C 353 - ACTTGTTTCTCACTTCATCT K|124|N silent|AAG>AAA|K|124 DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 -0.7478830297641806 Q08162 0.11645177751779555 47.831700048441526 35.0 0.0 no 12937 chrXV_285063 32604 essential YOL021C 344 - TCACTTCATCTAGGACAATC V|121|L V|121|M silent|GTG>GTC|V|121 silent|GTG>GTA|V|121 DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 -0.6051894701716529 Q08162 0.5807253122329712 0.015799827873706818 43.427801653632905 40.0 0.0 no 12938 chrXV_285064 32605 essential YOL021C 343 - CACTTCATCTAGGACAATCT V|121|L V|121|M E|120|Q E|120|K DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 -2.132446371987515 Q08162 0.5807253122329712 0.015799827873706818 0.0 0.0 44.304124346145954 40.0 0.0 yes 12939 chrXV_285065 32606 essential YOL021C 342 - ACTTCATCTAGGACAATCTG V|121|L V|121|M E|120|Q E|120|K DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 -0.4136145083993668 Q08162 0.5807253122329712 0.015799827873706818 0.0 0.0 42.945954889206575 40.0 0.0 no 12940 chrXV_285105 32608 essential YOL021C 302 - AACAATTCGGATTCTCTAAA C|107|S C|107|Y DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 0.9129201950075924 Q08162 0.4032580554485321 1.0 36.93613112832753 30.0 0.0 no 12941 chrXV_285144r 32609 essential YOL021C 260 + CGTCGTCTTGGATACCAACG silent|GTC>GTG|V|88 silent|GTC>GTT|V|88 silent|GTC>GTG|V|89 silent|GTC>GTT|V|89 DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 -0.055455100677911116 Q08162 49.139160342024574 55.00000000000001 0.0 no 12942 chrXV_285161 32610 essential YOL021C 246 - ACGACGTAATGCTTACCAAT V|89|L V|89|I V|88|L V|88|I DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 -0.2748971010966719 Q08162 0.3771829903125763 0.36340388655662537 1.0 0.190791055560112 43.604547151222675 40.0 0.0 no 12943 chrXV_285223 32611 essential YOL021C 184 - CGGCAACTCATTTTGAGCAT L|67|F silent|TTG>TTA|L|67 E|66|D silent|GAG>GAA|E|66 DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 1 0 0 0.2710643730641738 Q08162 0.2910359501838684 0.5991356372833252 47.74127216178789 45.0 0.0 no 12944 chrXV_285225 32613 essential YOL021C 182 - GCAACTCATTTTGAGCATCG L|67|F silent|TTG>TTA|L|67 E|66|D silent|GAG>GAA|E|66 DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 1 0 0 -0.5333901456653367 Q08162 0.2910359501838684 0.5991356372833252 46.414856742320005 45.0 0.0 no 12945 chrXV_285269 32616 essential YOL021C 138 - GTACAACTTCTCGAAAGACA C|52|S C|52|Y S|51|T S|51|N DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 -2.5083292629835294 Q08162 0.0 0.0 0.5079838037490845 0.4068684279918671 40.39710124202378 40.0 0.0 yes 12946 chrXV_285270 32617 essential YOL021C 137 - TACAACTTCTCGAAAGACAT C|52|S C|52|Y S|51|T S|51|N DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 -1.3256422784434814 Q08162 0.0 0.0 0.5079838037490845 0.4068684279918671 38.137079634222346 35.0 0.0 no 12947 chrXV_285349r 32618 essential YOL021C 55 + TCACTCAGAAGGTGTTTGTA T|20|S T|20|I silent|GTC>GTG|V|19 silent|GTC>GTT|V|19 DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 -2.064204585202098 Q08162 0.550744891166687 0.434588760137558 45.932092363048135 40.0 0.0 yes 12948 chrXV_285382 32620 essential YOL021C 25 - ATCTGCAAGTCTCTTCCGTC D|15|H D|15|N A|14|P A|14|T DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 1.290629038691566 Q08162 0.11672542244195938 0.5286391973495483 0.22956722974777224 0.4627638757228851 54.088968605221616 50.0 0.0 no 12949 chrXV_285383 32621 essential YOL021C 24 - TCTGCAAGTCTCTTCCGTCT D|15|H D|15|N A|14|P A|14|T DIS3 homolog of S. pombe dis3 (chromosome DISjunction) 1001.0 0 0 0 0 0.1606025680789949 Q08162 0.11672542244195938 0.5286391973495483 0.22956722974777224 0.4627638757228851 56.04584574576438 50.0 0.0 no 12950 chrXV_307954 32625 essential YOL010W 16 + CCAAATACACCACTTTCCAA silent|CCC>CCG|P|6 silent|CCC>CCT|P|6 RCL1 Rna 3'-terminal phosphate Cyclase Like 367.0 0 0 0 0 -0.5652976425550528 Q08096 45.44229867576394 40.0 1.0 no 12951 chrXV_307969 32627 essential YOL010W 31 + TCCAAGGGTCACAAAATTTT Q|12|E Q|12|* F|11|L silent|TTC>TTT|F|11 RCL1 Rna 3'-terminal phosphate Cyclase Like 367.0 0 0 0 0 -2.377283077439323 Q08096 1.0 0.20252327620983124 -0.15015999972820282 0.8096600174903871 1.7061200141906738 41.67237811299265 35.0 1.0 yes 12952 chrXV_307970r 32628 essential YOL010W 35 - ACCTAAAATTTTGTGACCCT R|18|T R|18|K R|18|S silent|AGG>AGA|R|18 RCL1 Rna 3'-terminal phosphate Cyclase Like 367.0 0 0 0 0 -0.0910511557069068 Q08096 0.10485118627548218 0.06380576640367508 0.033848334103822715 0.5175399780273438 -0.5111399888992311 0.6687999963760376 44.66146314220504 35.0 1.0 no 12953 chrXV_307999 32630 essential YOL010W 61 + TCGTCTTGGCAACATTATCA I|21|M silent|ATC>ATT|I|21 silent|GTC>GTG|V|22 silent|GTC>GTT|V|22 RCL1 Rna 3'-terminal phosphate Cyclase Like 367.0 0 0 0 0 0.34162819373154263 Q08096 0.1001749336719513 -0.007739999797195195 46.619079816965154 40.0 1.0 no 12954 chrXV_308064r 32631 essential YOL010W 129 - ACTTCATAATCTTTCAGACC V|50|L V|50|M E|49|Q E|49|K RCL1 Rna 3'-terminal phosphate Cyclase Like 367.0 0 0 0 0 0.4648356311722734 Q08096 0.2012578248977661 0.055631712079048164 0.07705686241388321 0.010185041464865208 -0.9370999932289124 -1.0511000156402588 2.7337400913238525 3.804620027542114 43.113906808337106 35.0 1.0 no 12955 chrXV_308169r 32635 essential YOL010W 234 - GCACCACCAACTATGATACC G|84|A G|84|D A|85|P A|85|T RCL1 Rna 3'-terminal phosphate Cyclase Like 367.0 0 0 0 0 -2.036381286514218 Q08096 0.0 0.0 0.2331271320581436 0.642535924911499 2.5744800567626958 2.7960400581359863 -0.27261999249458313 0.1598999947309494 -0.2802000045776367 -0.2753199934959412 50.092464179522274 50.0 1.0 yes 12956 chrXV_308170r 32636 essential YOL010W 235 - TGCACCACCAACTATGATAC A|85|P A|85|T G|84|A G|84|D RCL1 Rna 3'-terminal phosphate Cyclase Like 367.0 0 0 0 0 -0.4531153774844146 Q08096 0.2331271320581436 0.642535924911499 0.0 0.0 -0.27261999249458313 0.1598999947309494 2.5744800567626958 2.7960400581359863 -0.2802000045776367 -0.2753199934959412 46.54505833110375 45.0 1.0 no 12957 chrXV_308201 32637 essential YOL010W 263 + TATCTGCCCTAGTTCCAAAC I|89|M silent|ATC>ATT|I|89 C|90|W silent|TGC>TGT|C|90 RCL1 Rna 3'-terminal phosphate Cyclase Like 367.0 0 0 0 0 0.6609999058707241 Q08096 0.005694821011275053 0.0 -0.028100000694394108 38.84828186035156 0.4763999879360199 21.369319915771484 50.325696897863615 45.0 1.0 no 12958 chrXV_308234 32640 essential YOL010W 296 + CGTCGAACCAATGCTATATT silent|GTC>GTG|V|100 silent|GTC>GTT|V|100 RCL1 Rna 3'-terminal phosphate Cyclase Like 367.0 0 0 0 0 -0.3420932891291191 Q08096 43.670310580543116 40.0 1.0 no 12959 chrXV_308320r 32642 essential YOL010W 385 - CCATTTGATAGCTTCAATAC W|135|S W|135|* RCL1 Rna 3'-terminal phosphate Cyclase Like 367.0 0 0 0 0 -1.7197823810573518 Q08096 0.21816357970237726 1.7798600196838381 2.1300199031829834 42.032829501105205 35.0 1.0 no 12960 chrXV_308349 32643 essential YOL010W 411 + ATGCCCGTTATGGAAAAATT P|139|A P|139|S P|139|R P|139|L RCL1 Rna 3'-terminal phosphate Cyclase Like 367.0 0 0 0 0 -0.7337856047052465 Q08096 0.09286119788885117 0.01996051706373692 0.003421514527872205 0.004691786132752895 2.522459983825684 2.6181600093841557 1.3779200315475464 2.0698800086975098 42.14119490792223 35.0 1.0 no 12961 chrXV_308352r 32644 essential YOL010W 417 - ACGCCAAATTTTTCCATAAC G|145|A G|145|D V|146|L V|146|I RCL1 Rna 3'-terminal phosphate Cyclase Like 367.0 0 0 0 0 0.10373591328189176 Q08096 0.2924844026565552 0.4440341293811798 0.36801424622535706 1.0 3.4818999767303467 4.512420177459717 0.05462000146508217 1.03357994556427 42.47077357315561 35.0 1.0 no 12962 chrXV_308386r 32645 essential YOL010W 451 - ACCTCTTTTCAAAGTATGTA G|157|R G|157|S G|157|A G|157|D RCL1 Rna 3'-terminal phosphate Cyclase Like 367.0 0 0 0 0 0.4602770185309161 Q08096 0.0 0.0 0.0 0.0 36.46408081054688 9.557760238647461 5.0097999572753915 27.69622039794922 42.10605497019708 30.0 1.0 no 12963 chrXV_308415r 32647 essential YOL010W 480 - TGCACTTCGCCACCTCCTAG silent|GTG>GTC|V|166 silent|GTG>GTA|V|166 V|166|L V|166|M RCL1 Rna 3'-terminal phosphate Cyclase Like 367.0 0 0 0 0 -0.6827316837915623 Q08096 0.027530800551176068 0.005129717756062746 0.07962000370025635 2.612260103225708 59.48382936560108 60.0 1.0 no 12964 chrXV_308466r 32648 essential YOL010W 531 - TCTATTTCATGCATAGTTAT D|184|H D|184|N RCL1 Rna 3'-terminal phosphate Cyclase Like 367.0 0 0 0 0 -0.33190452323825137 Q08096 0.009198185056447985 0.01787593588232994 0.4208599925041199 0.32194000482559204 40.717064402153476 25.0 1.0 no 12965 chrXV_308493 32649 essential YOL010W 555 + CCCATAATTTCATCGATTAC silent|CCC>CCG|P|186 silent|CCC>CCT|P|186 P|186|R P|186|L RCL1 Rna 3'-terminal phosphate Cyclase Like 367.0 0 0 0 0 -0.5774663006274271 Q08096 0.015938516706228256 0.009199729189276695 5.332399845123291 3.3048999309539795 42.66577486460619 35.0 1.0 no 12966 chrXV_308494r 32650 essential YOL010W 559 - ACCGGTAATCGATGAAATTA G|193|R G|193|S G|193|A G|193|D RCL1 Rna 3'-terminal phosphate Cyclase Like 367.0 0 0 0 0 0.2591674113996812 Q08096 0.05476826801896095 0.02054474502801895 0.03080128692090512 0.014988278038799763 20.302759170532227 10.235540390014648 5.016540050506592 19.729480743408203 39.5634428744101 35.0 1.0 no 12967 chrXV_308530r 32651 essential YOL010W 595 - CACAAGCGACGGACTTACTC V|205|L V|205|M silent|TCG>TCC|S|203 silent|TCG>TCA|S|203 RCL1 Rna 3'-terminal phosphate Cyclase Like 367.0 0 0 0 0 -0.7949707889920437 Q08096 0.08881030231714249 0.041167568415403366 1.694280028343201 1.2573000192642212 47.242722264134386 55.00000000000001 1.0 no 12968 chrXV_308541r 32652 essential YOL010W 606 - ATCATTCTATTCACAAGCGA M|208|I M|208|I R|207|T R|207|K RCL1 Rna 3'-terminal phosphate Cyclase Like 367.0 0 0 0 0 0.198883513734821 Q08096 0.9693270325660706 0.9693270325660706 0.0 0.0 0.8277400135993958 0.8277400135993958 2.107140064239502 -0.19679999351501465 42.98495185785271 35.0 1.0 no 12969 chrXV_308651 32660 essential YOL010W 713 + TCCAGGCTGGGGTATTACTT P|239|R P|239|L P|239|A P|239|S RCL1 Rna 3'-terminal phosphate Cyclase Like 367.0 0 0 0 0 -0.8536024728520504 Q08096 0.0 0.0 0.0 0.0 -0.09431999921798706 0.476859986782074 0.930299997329712 1.5215799808502195 55.16816254774949 50.0 1.0 no 12970 chrXV_308652r 32661 essential YOL010W 717 - ACCAAAGTAATACCCCAGCC L|245|F silent|TTG>TTA|L|245 V|246|L V|246|I RCL1 Rna 3'-terminal phosphate Cyclase Like 367.0 0 0 0 0 0.6855608644878428 Q08096 0.011888347566127777 0.22134877741336825 0.04621678218245506 6.065400123596191 -0.07897999882698059 -1.0366799831390379 51.74184934191391 50.0 1.0 no 12971 chrXV_308739r 32664 essential YOL010W 804 - ACTTTTTCACCAAGTTCTTC V|275|L V|275|I RCL1 Rna 3'-terminal phosphate Cyclase Like 367.0 0 0 0 0 0.12077567013760518 Q08096 0.12287362664937973 0.15956050157546994 1.79885995388031 0.5415199995040894 45.880635686777744 35.0 1.0 no 12972 chrXV_315907 32666 essential YOL005C 249 - GCGTTTTTCAAGGCATCCTT A|90|P A|90|T RPB11 RNA Polymerase B 120.0 0 0 0 0 -1.2306806500867706 P38902 0.02084677666425705 0.07431710511445999 6.379960060119629 1.997120022773743 5.825039863586426 2.5216600894927983 52.809484548085486 45.0 0.0 no 12973 chrXV_315957 32669 essential YOL005C 199 - CAGCTTGAAACGAGCGAAGA K|72|N silent|AAG>AAA|K|72 RPB11 RNA Polymerase B 120.0 0 0 0 0 -0.3120616641831009 P38902 0.6014626026153564 0.94624000787735 43.42064249517637 50.0 0.0 no 12974 chrXV_316022 32671 essential YOL005C 134 - TCAGAAGTTCTGCACGAATC silent|CTG>CTC|L|51 silent|CTG>CTA|L|51 RPB11 RNA Polymerase B 120.0 0 0 0 0 0.5624839489475 P38902 44.226459348638286 45.0 0.0 no 12975 chrXV_316071 32672 essential YOL005C 85 - AAACGTTATCACTACTGCGT silent|ACG>ACC|T|34 silent|ACG>ACA|T|34 RPB11 RNA Polymerase B 120.0 0 0 0 0 1.2206473734458787 P38902 43.81237937644971 40.0 0.0 no 12976 chrXV_316072 32673 essential YOL005C 84 - AACGTTATCACTACTGCGTT silent|ACG>ACC|T|34 silent|ACG>ACA|T|34 RPB11 RNA Polymerase B 120.0 0 0 0 0 0.6611187221587544 P38902 45.51182279560065 40.0 0.0 no 12977 chrXV_316073 32674 essential YOL005C 83 - ACGTTATCACTACTGCGTTG silent|ACG>ACC|T|34 silent|ACG>ACA|T|34 RPB11 RNA Polymerase B 120.0 0 0 0 0 0.5342010047666098 P38902 47.02509366652152 45.0 0.0 no 12978 chrXV_316130r 32680 essential YOL005C 23 + ACTGTTCCTTCTGGGTGAAG L|9|V silent|CTG>TTG|L|9 F|10|L silent|TTC>TTT|F|10 RPB11 RNA Polymerase B 120.0 0 0 0 0 -0.5950104688238125 P38902 0.2748526632785797 0.0718645304441452 1.5823800563812256 0.615119993686676 0.4633800089359283 -0.6111599802970886 51.36659916705214 50.0 0.0 no 12979 chrXV_333657 32681 essential YOR004W 65 + CCGTGAGCCATATCAAGTTT R|23|G R|23|C UTP23 U Three-associated Protein 254.0 0 0 0 0 0.3994030741524036 Q12339 0.8994590044021606 0.8926740288734436 0.00716480566188693 0.0013790644006803632 1.0849900245666504 1.0943440198898315 50.05628800627046 45.0 1.0 no 12980 chrXV_333657r 32682 essential YOR004W 68 - CCAAAACTTGATATGGCTCA L|29|F silent|TTG>TTA|L|29 V|28|L V|28|I UTP23 U Three-associated Protein 254.0 0 0 0 0 -1.203246304554654 Q12339 0.9587849974632264 0.9539830088615416 0.9574310183525084 0.012802495621144772 0.030628608539700505 0.2861199975013733 6.0672969818115225 2.840794086456299 0.4817000031471253 43.25000643093534 40.0 1.0 no 12981 chrXV_333712 32683 essential YOR004W 120 + TCTAATTTTAATCTACCGAG S|41|C S|41|F UTP23 U Three-associated Protein 254.0 0 0 0 0 0.926988654925818 Q12339 0.945252001285553 0.9294660091400146 0.1801508665084839 0.9554330706596376 -0.22089000046253204 -0.7052140235900879 -0.11713000386953355 -0.2896900177001953 38.02496333076084 30.0 1.0 no 12982 chrXV_333727r 32684 essential YOR004W 138 - AACGTTCTTTTCAACCCACT silent|ACG>ACC|T|52 silent|ACG>ACA|T|52 R|51|T R|51|K UTP23 U Three-associated Protein 254.0 0 0 0 0 -0.5512486110330015 Q12339 0.932735025882721 0.955805003643036 0.008137478493154049 0.03693326562643051 0.13027800619602206 0.19383400678634646 0.5001299977302551 0.2852399945259094 48.02456729400757 40.0 1.0 no 12983 chrXV_333877r 32687 essential YOR004W 288 - ATGCACTCCGCAGGTGACTT C|102|S C|102|Y E|101|D silent|GAG>GAA|E|101 UTP23 U Three-associated Protein 254.0 0 0 0 0 -4.963612589763344 Q12339 0.9421560168266296 0.9290120005607604 0.94931298494339 0.018603716045618057 0.001578962430357933 0.6337341070175171 5.889676094055176 37.24490737915039 -0.016308000311255455 56.134384119223796 55.00000000000001 1.0 yes 12984 chrXV_334008 32690 essential YOR004W 416 + CCATTTAACCAGGTCTGTTA H|140|D H|140|Y UTP23 U Three-associated Protein 254.0 0 0 0 0 0.7441269437766398 Q12339 0.9473130106925964 0.9489949941635132 0.008829253725707531 1.0 -0.5668540000915527 -0.5313460230827332 1.0075299739837646 -1.6395299434661863 48.459046275671206 40.0 1.0 no 12985 chrXV_334058r 32692 essential YOR004W 469 - TTCAGTAATCTTGCTTGCCT E|163|Q E|163|K UTP23 U Three-associated Protein 254.0 0 0 0 0 0.1402779969038912 Q12339 0.956179976463318 0.9475290179252625 0.0 0.0 50.654459251523924 40.0 1.0 no 12986 chrXV_341323r 32694 high_effect YOR008C 781 + TCATAAATGGCGGACCAGGA F|261|L silent|TTC>TTT|F|261 SLG1 Synthetic Lethal with Gap 378.0 0 0 0 0 0.25343426037588435 P54867 47.78592484808297 50.0 0.0 no 12987 chrXV_341414 32702 high_effect YOR008C 693 - TCCTCGAAGCTACCTGAAGA E|237|D silent|GAG>GAA|E|237 E|238|Q E|238|K SLG1 Synthetic Lethal with Gap 378.0 0 0 0 0 0.5187646432153616 P54867 49.529721769425976 50.0 0.0 no 12988 chrXV_341437r 32703 high_effect YOR008C 667 + CTTCATTTTCATCTAATCAC S|224|* S|224|L SLG1 Synthetic Lethal with Gap 378.0 0 0 0 0 1.0862436463330931 P54867 39.94932117084989 30.0 0.0 no 12989 chrXV_341438r 32704 high_effect YOR008C 666 + TCTTCATTTTCATCTAATCA S|223|C S|223|F S|224|* S|224|L SLG1 Synthetic Lethal with Gap 378.0 0 0 0 0 0.3825310593492116 P54867 0.945252001285553 0.9294660091400146 0.0 0.0 40.441611004531694 25.0 0.0 no 12990 chrXV_341484 32705 high_effect YOR008C 623 - CAACTGGTTTTATCGCCTCT V|214|L V|214|I SLG1 Synthetic Lethal with Gap 378.0 0 0 0 0 0.6463346991964852 P54867 50.673222530817156 45.0 0.0 no 12991 chrXV_341533r 32707 high_effect YOR008C 571 + TCAGACACATTAATATGAAG silent|GTC>GTG|V|191 silent|GTC>GTT|V|191 H|193|D H|193|Y SLG1 Synthetic Lethal with Gap 378.0 0 0 0 0 0.2139638302299474 P54867 34.057905933715226 30.0 0.0 no 12992 chrXV_341614 32712 high_effect YOR008C 493 - GCCTACAATTGCCCCTACAT G|171|R G|171|S G|171|A G|171|D SLG1 Synthetic Lethal with Gap 378.0 0 0 0 0 -1.2141078742465543 P54867 55.804166573752745 50.0 0.0 no 12993 chrXV_341671 32714 high_effect YOR008C 436 - GTCAGATCCAGCTGTACCTG D|152|H D|152|N SLG1 Synthetic Lethal with Gap 378.0 0 0 0 0 -0.5934554221532728 P54867 55.670948118011104 55.00000000000001 0.0 no 12994 chrXV_341704 32717 high_effect YOR008C 403 - ATTCTGTGCACTTGCCGTGA Q|140|H silent|CAG>CAA|Q|140 SLG1 Synthetic Lethal with Gap 378.0 0 0 0 0 -0.2605495031183281 P54867 54.826342478725856 50.0 0.0 no 12995 chrXV_341826r 32719 high_effect YOR008C 278 + CTCGCTAACTTCGGATACTT S|94|W S|94|L L|95|V silent|CTA>TTA|L|95 SLG1 Synthetic Lethal with Gap 378.0 0 0 0 0 -0.4965678354101713 P54867 0.9288619756698608 0.9298099875450134 0.01769950427114964 0.3013991117477417 46.862205357975206 45.0 0.0 no 12996 chrXV_341872 32721 high_effect YOR008C 235 - ACTCTGTGACGTTGAAATAG Q|84|H silent|CAG>CAA|Q|84 S|85|T S|85|N SLG1 Synthetic Lethal with Gap 378.0 0 0 0 0 -0.6348641946579084 P54867 0.9512869715690612 0.9536849856376648 0.8118481636047363 0.1200852245092392 40.25715995882484 40.0 0.0 no 12997 chrXV_341896 32724 high_effect YOR008C 211 - AGCTGCTTGAGTTGACTCGG A|77|P A|77|T A|76|P A|76|T SLG1 Synthetic Lethal with Gap 378.0 0 0 0 0 0.5367837559130411 P54867 52.9117045987357 55.00000000000001 0.0 no 12998 chrXV_341943r 32725 high_effect YOR008C 161 + ATCATCAACTACATCATCAA S|55|* S|55|L S|56|* S|56|L SLG1 Synthetic Lethal with Gap 378.0 0 0 0 0 -1.3331027130628408 P54867 38.898406441050675 30.0 0.0 no 12999 chrXV_370691 32732 essential YOR020C 134 - CTACGGCAACAACTTCAGCT V|51|L V|51|I A|50|P A|50|T HSP10 Heat Shock Protein 106.0 0 0 0 0 -0.2930712943471265 P38910 0.9539830088615416 0.9574310183525084 0.9573720097541808 0.9523990154266356 0.01329059712588787 0.05696333199739456 0.0046534636057913295 0.003716783132404089 0.5052199959754944 -0.19991999864578247 5.637040138244629 -0.4457800090312958 48.38881875341389 50.0 0.0 no 13000 chrXV_370717 32733 essential YOR020C 108 - AACTTCTCCACGTTCTTTTC K|42|N silent|AAG>AAA|K|42 E|41|D silent|GAG>GAA|E|41 HSP10 Heat Shock Protein 106.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.3130334184189172 P38910 0.9355990290641784 0.94931298494339 0.06216658279299736 0.6339259743690491 48.31166278070754 40.0 0.0 no 13001 chrXV_370749r 32734 essential YOR020C 73 + CACAAGCAAAGACAGCATCC Q|26|E Q|26|* A|27|G A|27|V HSP10 Heat Shock Protein 106.0 0 1 0 0 -0.16719751705067082 P38910 0.9590039849281312 0.9484469890594482 0.9504740238189696 1.0 0.011735630221664906 0.1019272282719612 0.11299999803304672 -0.19183999300003046 45.57529613911072 50.0 0.0 no 13002 chrXV_370750r 32735 essential YOR020C 72 + GCACAAGCAAAGACAGCATC Q|26|E Q|26|* A|25|G A|25|V HSP10 Heat Shock Protein 106.0 0 1 0 0 -0.4686178251418592 P38910 0.9590039849281312 0.9484469890594482 0.9504740238189696 1.0 0.27609583735466003 0.08330325037240982 -0.5906000137329102 0.5462599992752075 45.417788284829605 50.0 0.0 no 13003 chrXV_370772r 32737 essential YOR020C 50 + TGTCCTTGTCCAAAGAATCA silent|GTC>GTG|V|18 silent|GTC>GTT|V|18 L|19|V L|19|F HSP10 Heat Shock Protein 106.0 0 0 0 1 0.7394336897619157 P38910 0.9512209892272948 0.9587849974632264 0.03205283358693123 0.0036952942609786983 46.27021045933885 40.0 0.0 no 13004 chrXV_374412r 32741 no_effect YOR022C 1423 + CTCAATTGAACAAAACATAT Q|476|E Q|476|* DDL1 DDHD Domain-containing Lipase 715.0 0 0 0 0 -0.02717004664200872 Q12204 0.26506829261779785 31.793533600953428 25.0 0.0 no 13005 chrXV_374502 32742 no_effect YOR022C 1336 - GTCAGCCAGTAGCTTCCTCA D|452|H D|452|N A|451|P A|451|T DDL1 DDHD Domain-containing Lipase 715.0 0 0 0 0 0.9802471809908936 Q12204 0.0 0.0 0.02830586582422256 0.01995036192238331 61.26572087498306 55.00000000000001 0.0 no 13006 chrXV_374503 32743 no_effect YOR022C 1335 - TCAGCCAGTAGCTTCCTCAA D|452|H D|452|N A|451|P A|451|T DDL1 DDHD Domain-containing Lipase 715.0 0 0 0 0 0.3296953141361304 Q12204 0.0 0.0 0.02830586582422256 0.01995036192238331 56.1906173043535 50.0 0.0 no 13007 chrXV_374585r 32746 no_effect YOR022C 1250 + TTTCCAAACGGATGCTAAGG F|418|L silent|TTC>TTT|F|418 Q|419|E Q|419|* DDL1 DDHD Domain-containing Lipase 715.0 0 0 0 0 0.5096181555246293 Q12204 0.0614054799079895 0.6973591446876526 44.02954567285059 45.0 0.0 no 13008 chrXV_374610 32747 no_effect YOR022C 1228 - TATCGAGTGCCTCCAGGTGA silent|TCG>TCC|S|415 silent|TCG>TCA|S|415 DDL1 DDHD Domain-containing Lipase 715.0 0 0 0 0 0.2230955639546708 Q12204 56.51505724051219 55.00000000000001 0.0 no 13009 chrXV_374622r 32748 no_effect YOR022C 1213 + TTCAAGTGCTACCCATCACC Q|406|E Q|406|* DDL1 DDHD Domain-containing Lipase 715.0 0 0 0 0 0.7042912787258597 Q12204 0.0 53.65835909021217 50.0 0.0 no 13010 chrXV_374727r 32750 no_effect YOR022C 1108 + CACACACGGTAAATCTACTT H|371|D H|371|Y H|371|Q silent|CAC>CAT|H|371 DDL1 DDHD Domain-containing Lipase 715.0 0 0 0 0 -0.2540231365538182 Q12204 0.0 0.0 0.0 41.99431180351331 40.0 0.0 no 13011 chrXV_374788r 32751 no_effect YOR022C 1047 + ATACTATGCGTTCACGGTAT L|351|V silent|CTA>TTA|L|351 DDL1 DDHD Domain-containing Lipase 715.0 0 0 0 0 -0.43704944296584025 Q12204 0.08665896952152252 46.34519129143098 40.0 0.0 no 13012 chrXV_374777r 32753 no_effect YOR022C 1058 + TCACGGTATAGGTCAGACTT H|354|Q silent|CAC>CAT|H|354 H|354|D H|354|Y DDL1 DDHD Domain-containing Lipase 715.0 0 0 0 0 0.2203564226408301 Q12204 0.0 0.0 0.0 48.26809567405043 45.0 0.0 no 13013 chrXV_374741r 32754 no_effect YOR022C 1094 + ATACGTAAATTTCGCACACA Y|366|* silent|TAC>TAT|Y|366 DDL1 DDHD Domain-containing Lipase 715.0 0 0 0 0 -0.09067141495553532 Q12204 40.857040077278384 35.0 0.0 no 13014 chrXV_374794r 32755 no_effect YOR022C 1041 + AACTTGATACTATGCGTTCA N|348|K silent|AAC>AAT|N|348 DDL1 DDHD Domain-containing Lipase 715.0 0 0 0 0 -0.024350399691553976 Q12204 0.018112780526280403 42.58594034164821 35.0 0.0 no 13015 chrXV_374902r 32756 no_effect YOR022C 933 + AACAATGCAGATAACAGTCA N|312|K silent|AAC>AAT|N|312 DDL1 DDHD Domain-containing Lipase 715.0 0 0 0 0 0.2485760874040876 Q12204 0.984066367149353 38.95758277523049 35.0 0.0 no 13016 chrXV_374986r 32757 no_effect YOR022C 849 + GACTTTTTACAGTTGTTCAA D|284|E silent|GAC>GAT|D|284 DDL1 DDHD Domain-containing Lipase 715.0 0 0 0 0 0.4781640630520731 Q12204 0.4055046439170837 41.17414103141709 30.0 0.0 no 13017 chrXV_374948r 32758 no_effect YOR022C 887 + TCAAGATGATGCACAGAGCT Q|297|E Q|297|* DDL1 DDHD Domain-containing Lipase 715.0 0 0 0 0 0.2125079083797397 Q12204 1.0 46.0044329870741 45.0 0.0 no 13018 chrXV_375008r 32759 no_effect YOR022C 827 + TTCAAACCTCTTCAATTTAT S|277|* S|277|L N|278|K silent|AAC>AAT|N|278 DDL1 DDHD Domain-containing Lipase 715.0 0 0 0 0 0.3057760167172856 Q12204 0.2160084992647171 0.09269915521144867 38.84875440708811 25.0 0.0 no 13019 chrXV_375116r 32762 no_effect YOR022C 719 + ACAGACATCCACATCTTTTA Q|241|E Q|241|* T|242|R T|242|I DDL1 DDHD Domain-containing Lipase 715.0 0 1 0 0 0.475016215556561 Q12204 1.0 0.4539379179477692 0.12761041522026062 44.94721734693394 35.0 0.0 no 13020 chrXV_375257r 32764 no_effect YOR022C 578 + ACAAACTGCATTTTTACTAT Q|194|E Q|194|* T|195|S T|195|I DDL1 DDHD Domain-containing Lipase 715.0 0 0 0 0 -0.2678547317583273 Q12204 0.3850280940532684 0.4317420721054077 0.03481122478842735 37.61706450209016 25.0 0.0 no 13021 chrXV_375312 32765 no_effect YOR022C 526 - TTCGTTCTCATCTTTATTGC E|182|Q E|182|K E|180|D silent|GAG>GAA|E|180 DDL1 DDHD Domain-containing Lipase 715.0 0 0 0 0 -0.11852590283622585 Q12204 0.5608181357383728 46.38222579966464 35.0 0.0 no 13022 chrXV_375352 32766 no_effect YOR022C 486 - CCTTCGTTTTCTTTATCGAC G|169|R G|169|R E|168|Q E|168|K DDL1 DDHD Domain-containing Lipase 715.0 0 0 0 0 -0.27546908827757555 Q12204 47.30205848946889 40.0 0.0 no 13023 chrXV_375353 32767 no_effect YOR022C 485 - CTTCGTTTTCTTTATCGACT E|168|Q E|168|K DDL1 DDHD Domain-containing Lipase 715.0 0 0 0 0 0.5030083595669621 Q12204 45.291702901338 35.0 0.0 no 13024 chrXV_375465 32769 no_effect YOR022C 373 - ATACAACCCTTCAATTTCGG L|130|F silent|TTG>TTA|L|130 silent|GGG>GGC|G|129 silent|GGG>GGA|G|129 DDL1 DDHD Domain-containing Lipase 715.0 0 0 0 0 -0.3034768072059921 Q12204 0.7064453363418579 44.988201083227814 40.0 0.0 no 13025 chrXV_375472r 32770 no_effect YOR022C 363 + GATCTTACCTCCGAAATTGA L|123|V L|123|F DDL1 DDHD Domain-containing Lipase 715.0 0 0 0 0 0.5084420101757532 Q12204 0.023536454886198044 0.1087525114417076 44.723279973709744 40.0 0.0 no 13026 chrXV_375471r 32774 no_effect YOR022C 364 + ATCTTACCTCCGAAATTGAA L|123|V L|123|F T|124|S T|124|I DDL1 DDHD Domain-containing Lipase 715.0 0 0 0 0 1.2788466057723635 Q12204 0.023536454886198044 0.1087525114417076 0.17293596267700195 0.017689000815153122 42.25384838665775 35.0 0.0 no 13027 chrXV_400425r 32778 high_effect YOR036W 80 - CAACCTCTTCTTTCAACGTT V|33|L V|33|I E|32|D silent|GAG>GAA|E|32 PEP12 carboxyPEPtidase Y-deficient 288.0 0 0 0 0 0.9182295766691924 P32854 1.0097500085830688 1.0187699794769287 1.0132399797439575 0.5690928101539612 1.0 0.4732301831245422 46.68675290257431 40.0 1.0 no 13028 chrXV_400785 32782 high_effect YOR036W 437 + ATCTCTTGAAGCAAGTGAGA S|147|C S|147|F L|148|V L|148|F PEP12 carboxyPEPtidase Y-deficient 288.0 0 1 0 0 0.3653117360759903 P32854 0.7566850185394287 0.8403999805450441 0.8906059861183167 0.8947499990463257 0.06950435042381288 0.0847565084695816 0.4327714443206787 0.3928041458129883 0.7544806599617004 -0.2332753539085388 43.289811450476854 40.0 1.0 no 13029 chrXV_400852 32783 high_effect YOR036W 504 + TCAAAAAGTACTCGAATACC S|169|* S|169|L PEP12 carboxyPEPtidase Y-deficient 288.0 0 0 0 0 0.31434878102066754 P32854 0.9493749737739564 0.26219722628593445 36.35036137259783 35.0 1.0 no 13030 chrXV_400870r 32784 high_effect YOR036W 525 - TCAATGACTATTTGGCTGCC E|182|Q E|182|K PEP12 carboxyPEPtidase Y-deficient 288.0 0 0 0 0 0.4257966930119448 P32854 0.9520450234413148 0.8583719730377197 0.06480328738689423 0.05643488094210625 48.74886569040223 45.0 1.0 no 13031 chrXV_400900r 32785 high_effect YOR036W 555 - GCAAACTCTTCGTTATTTAT A|192|P A|192|T E|190|D silent|GAG>GAA|E|190 PEP12 carboxyPEPtidase Y-deficient 288.0 0 0 0 0 0.025599371220213413 P32854 0.8588250279426575 0.9670310020446776 0.8631439805030823 0.1251285821199417 0.6297046542167664 0.19097724556922915 40.933577488921344 30.0 1.0 no 13032 chrXV_414864r 32788 essential YOR046C 1021 + AAACCGCAAACGTTTTATAT T|342|S T|342|I silent|ACC>ACG|T|342 silent|ACC>ACT|T|342 DBP5 Dead Box Protein 482.0 0 0 0 0 -1.2384546573445037 P20449 0.31205251812934875 0.039526663720607765 0.8380799889564514 -0.8023999929428101 38.50523193026624 30.0 0.0 no 13033 chrXV_415164 32791 essential YOR046C 724 - CTGCTGATCCAACATGTTAT Q|247|H silent|CAG>CAA|Q|247 DBP5 Dead Box Protein 482.0 0 0 0 0 -1.5254818930626923 P20449 0.07928740978240968 -0.09767000377178192 -0.6371600031852722 46.280778490188034 40.0 0.0 no 13034 chrXV_415223 32792 essential YOR046C 665 - GCATCAATTTTCTACGCATT M|228|I M|228|I L|227|F silent|TTG>TTA|L|227 DBP5 Dead Box Protein 482.0 0 0 0 0 0.5180069613814398 P20449 1.0 1.0 0.7443389892578125 3.1302599906921387 3.1302599906921387 0.3887900114059448 0.5425000190734863 44.8799246414024 35.0 0.0 no 13035 chrXV_415362 32797 essential YOR046C 526 - AACGACTTCTAGTGTTTGTC V|182|L V|182|I V|181|L V|181|I DBP5 Dead Box Protein 482.0 0 0 0 0 -1.6815354657821042 P20449 0.058619949966669076 0.8081022500991821 0.0 0.0 -0.6969999670982361 -0.4342000186443329 0.9788499474525452 0.13081002235412598 -0.467059999704361 -0.8701400160789491 44.491546213806714 40.0 0.0 no 13036 chrXV_415590r 32805 essential YOR046C 295 + TAGCACCAGAACTACTAAAG A|100|G A|100|V P|101|A P|101|S DBP5 Dead Box Protein 482.0 0 0 0 0 0.1992757961768281 P20449 0.27943289279937744 0.1963569223880768 0.3395595252513885 0.10445592552423476 0.5774499773979187 0.06460000574588776 1.1808500289916992 1.5750999450683594 0.6993799805641174 -0.1147800013422966 39.78759675510509 40.0 0.0 no 13037 chrXV_415637 32806 essential YOR046C 251 - CACTGTACAATGGAGAATTT S|90|T S|90|N DBP5 Dead Box Protein 482.0 0 1 0 0 -1.5974699088606017 P20449 0.0 0.0 0.6442000269889832 0.20000000298023224 39.049777522761424 35.0 0.0 no 13038 chrXV_415664r 32807 essential YOR046C 221 + GGTCAAACTTGCTGATATCC silent|GTC>GTG|V|75 silent|GTC>GTT|V|75 DBP5 Dead Box Protein 482.0 0 0 0 0 -0.6498298387537211 P20449 46.85491222882546 45.0 0.0 no 13039 chrXV_415781 32808 essential YOR046C 107 - AATCAGCAGTCTTTTCTGGT D|42|H D|42|N A|41|P A|41|T DBP5 Dead Box Protein 482.0 0 1 0 0 0.3568541792147485 P20449 0.046937473118305206 0.12610697746276855 0.2685678899288177 0.5589028596878052 49.350530787674415 40.0 0.0 no 13040 chrXV_419414 32810 essential YOR048C 2217 - AGTCTATCCTGATCGATGAA R|745|T R|745|K RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 -0.8088062833154659 Q02792 0.932735025882721 0.955805003643036 0.0 0.0 45.00226764834588 40.0 0.0 no 13041 chrXV_419465 32812 essential YOR048C 2166 - TTCTTACCATTCATATCTAT K|728|N silent|AAG>AAA|K|728 G|727|A G|727|D RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 0.19918286367925386 Q02792 0.9355990290641784 0.9499930143356324 0.9446240067481996 0.008069724775850773 0.0 0.0 41.733664709941756 25.0 0.0 no 13042 chrXV_419585 32813 essential YOR048C 2046 - ACACTCATCAATTGTTCGTA S|688|T S|688|N V|689|L V|689|I RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 -0.20408376156502625 Q02792 0.9512869715690612 0.9536849856376648 0.9539830088615416 0.9574310183525084 0.16665096580982208 0.1780913919210434 0.0 0.0 43.52699490437425 35.0 0.0 no 13043 chrXV_419637 32814 essential YOR048C 1994 - TCTCCAAGTGAGAAAACCCA E|671|Q E|671|K E|671|D silent|GAG>GAA|E|671 RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 0.5414041702970546 Q02792 0.956179976463318 0.9475290179252625 0.94931298494339 0.21694843471050265 0.5874639749526978 0.37769564986228943 46.42193354514552 45.0 0.0 no 13044 chrXV_419653r 32816 essential YOR048C 1975 + CTCTGGCAACAGATTTCCAT L|660|V silent|CTG>TTG|L|660 A|661|G A|661|V RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 0.29268971661060994 Q02792 0.9512209892272948 0.9484469890594482 0.9504740238189696 0.006829097401350737 0.0 0.0 49.345584663697366 45.0 0.0 no 13045 chrXV_419704r 32820 essential YOR048C 1924 + ACTATCAAGGTTGTGCCTCT Y|642|* silent|TAC>TAT|Y|642 Q|644|E Q|644|* RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 0.2219095964880366 Q02792 0.9590039849281312 0.0 51.960822386763255 45.0 0.0 no 13046 chrXV_419717r 32821 essential YOR048C 1911 + GTACTAATGTATTACTATCA L|639|V silent|CTA>TTA|L|639 RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 -0.06632106382431657 Q02792 0.9512209892272948 0.018543235957622528 36.769464625749094 25.0 0.0 no 13047 chrXV_419817 32823 essential YOR048C 1814 - TAGCTGTGTAATATCTTTCG A|611|P A|611|T RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 0.16546382266385462 Q02792 0.9573720097541808 0.9523990154266356 0.06304804980754852 0.061726681888103485 42.07101973283039 35.0 0.0 no 13048 chrXV_419901 32828 essential YOR048C 1730 - CGCTGACATTCACTGTGCTG S|583|T S|583|N V|582|L V|582|I RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 -0.14180262741082986 Q02792 0.9512869715690612 0.9536849856376648 0.9539830088615416 0.9574310183525084 0.8167409896850586 0.4858764410018921 0.4255388975143433 0.5020167827606201 51.646725326505354 55.00000000000001 0.0 no 13049 chrXV_419906 32829 essential YOR048C 1725 - ACATTCACTGTGCTGTGGAC V|582|L V|582|I silent|GTG>GTC|V|580 silent|GTG>GTA|V|580 RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 0.2931519742026195 Q02792 0.9539830088615416 0.9574310183525084 0.4255388975143433 0.5020167827606201 50.688056169533645 50.0 0.0 no 13050 chrXV_420220 32832 essential YOR048C 1411 - ATCACTCTGTTGCTTAACTT D|477|H D|477|N S|476|T S|476|N RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 0.07271632610284676 Q02792 0.9486550092697144 0.956179976463318 0.9512869715690612 0.9536849856376648 0.1362926959991455 0.5022209286689758 0.875299334526062 0.15420816838741302 45.59176838310884 35.0 0.0 no 13051 chrXV_420286 32834 essential YOR048C 1345 - TTTCAACCTTACCATATCAC L|454|F silent|TTG>TTA|L|454 R|453|S silent|AGG>AGA|R|453 RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 -0.2761204735642635 Q02792 0.9587849974632264 0.9087679982185364 0.7087962031364441 0.7395107746124268 44.140106171202774 35.0 0.0 no 13052 chrXV_420292r 32835 essential YOR048C 1336 + TGACCACCAGTGATATGGTA T|447|S T|447|I silent|ACC>ACG|T|447 silent|ACC>ACT|T|447 RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 -0.8773485320076034 Q02792 0.9491789937019348 0.9472420215606691 0.7200045585632324 0.40536877512931824 49.21289797674717 45.0 0.0 no 13053 chrXV_420341r 32836 essential YOR048C 1287 + CTGCAAATGTATGACACACA Q|431|E Q|431|* RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 -0.29111684689872763 Q02792 0.9590039849281312 0.4614511728286743 41.569023593428994 40.0 0.0 no 13054 chrXV_420398r 32837 essential YOR048C 1230 + GCGCAGAAAAATATGTCAAA Q|412|E Q|412|* A|411|G A|411|V RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 0.4942170789025192 Q02792 0.9590039849281312 0.9484469890594482 0.9504740238189696 1.0 0.31394755840301514 0.2898273468017578 36.62453593481257 35.0 0.0 no 13055 chrXV_420483r 32839 essential YOR048C 1145 + ACACCTTGGCTCCCGTGAGG H|383|Q silent|CAC>CAT|H|383 H|383|D H|383|Y RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 -0.3646578093554765 Q02792 0.9588389992713928 0.9473130106925964 0.9489949941635132 0.09475798904895782 0.12049083411693573 0.013980927877128124 60.685053316787844 65.0 0.0 no 13056 chrXV_420484r 32840 essential YOR048C 1144 + AACACCTTGGCTCCCGTGAG H|383|D H|383|Y H|383|Q silent|CAC>CAT|H|383 RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 -1.143857375604327 Q02792 0.9473130106925964 0.9489949941635132 0.9588389992713928 0.12049083411693573 0.013980927877128124 0.09475798904895782 56.61082198083824 60.0 0.0 no 13057 chrXV_420485r 32841 essential YOR048C 1143 + CAACACCTTGGCTCCCGTGA H|383|D H|383|Y H|383|Q silent|CAC>CAT|H|383 RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 -1.1272885719851855 Q02792 0.9473130106925964 0.9489949941635132 0.9588389992713928 0.12049083411693573 0.013980927877128124 0.09475798904895782 57.57588893581163 60.0 0.0 no 13058 chrXV_420506 32843 essential YOR048C 1125 - TGCAATAGCGTTTCAACAGA L|381|F silent|TTG>TTA|L|381 RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 0.413482599858958 Q02792 0.9587849974632264 0.01264740154147148 43.92499123856595 40.0 0.0 no 13059 chrXV_420551 32844 essential YOR048C 1080 - GTCATGTACGTTTTCAATTT M|366|I M|366|I RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 0.3264957802489804 Q02792 0.9553959965705872 0.9553959965705872 0.430222362279892 0.430222362279892 42.20980621516816 30.0 0.0 no 13060 chrXV_420732r 32847 essential YOR048C 896 + ATACTTGTCCGCTGAGTTAT Y|300|* silent|TAC>TAT|Y|300 RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 0.4889695872466895 Q02792 48.83650314812309 40.0 0.0 no 13061 chrXV_420757r 32848 essential YOR048C 871 + GGCTGCACATAAATGTTTTG L|292|V silent|CTG>TTG|L|292 H|293|D H|293|Y RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 -0.5317130422353714 Q02792 0.9512209892272948 0.9473130106925964 0.9489949941635132 0.0 0.03348233178257942 0.003938108682632446 43.52663766645776 40.0 0.0 no 13062 chrXV_420893 32849 essential YOR048C 738 - TCTCTTAGAATTTTAAAATG R|252|T R|252|K E|253|Q E|253|K RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 -0.9276829875913116 Q02792 0.932735025882721 0.955805003643036 0.956179976463318 0.9475290179252625 0.0 0.0 0.0 0.0 30.55661413236811 20.0 0.0 no 13063 chrXV_420959r 32851 essential YOR048C 669 + AACACAACGCACTGTATATA N|224|K silent|AAC>AAT|N|224 T|225|R T|225|I RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 0.2355878969434085 Q02792 0.9439849853515624 0.9476869702339172 0.9472420215606691 0.0 0.002476762980222702 0.0035332764964550725 39.836954744719954 35.0 0.0 no 13064 chrXV_421033 32852 essential YOR048C 598 - GTGCTCACCTTCACCTGGGA E|205|D silent|GAG>GAA|E|205 E|205|Q E|205|K RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 -2.864469793775913 Q02792 0.94931298494339 0.956179976463318 0.9475290179252625 0.0 0.0 0.0 60.71879825312334 60.0 0.0 yes 13065 chrXV_421036 32853 essential YOR048C 595 - CTCACCTTCACCTGGGACGG E|205|Q E|205|K G|204|A G|204|D RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 -3.7707241951442985 Q02792 0.956179976463318 0.9475290179252625 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 57.60909036019581 65.0 0.0 yes 13066 chrXV_421059 32857 essential YOR048C 572 - CGTCACTGATAATCACCTGC D|197|H D|197|N S|196|T S|196|N RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 0.4184979616537927 Q02792 0.9486550092697144 0.956179976463318 0.9512869715690612 0.9536849856376648 0.0 0.0 0.0 0.0 48.58131518193949 50.0 0.0 no 13067 chrXV_421137 32861 essential YOR048C 494 - CGGCAAGCTTATCCATAAAT A|171|P A|171|T RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 -0.3854759877136393 Q02792 0.9573720097541808 0.9523990154266356 0.0 0.0 44.11213088635049 40.0 0.0 no 13068 chrXV_421149r 32864 essential YOR048C 479 + CACTCCAGGCACCCCATTTA T|161|S T|161|I P|162|A P|162|S RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 0.14458837000253902 Q02792 0.9491789937019348 0.9472420215606691 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 58.930349448422135 55.00000000000001 0.0 no 13069 chrXV_421313 32871 essential YOR048C 318 - TGCTGGTTCATTTTGGCACG Q|112|H silent|CAG>CAA|Q|112 RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 -1.174614422361104 Q02792 0.9570760130882264 0.0 52.01492025169205 50.0 0.0 no 13070 chrXV_421427 32875 essential YOR048C 204 - TCATCTTCAGTCTCTGGAGG E|75|Q E|75|K D|74|H D|74|N RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 -0.018454113598927683 Q02792 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.0 0.0 0.008399644866585732 0.01707673817873001 52.00819626205424 50.0 0.0 no 13071 chrXV_421484r 32877 essential YOR048C 144 + AACTTGTATTTGGATATGAA N|49|K silent|AAC>AAT|N|49 RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 0.5175412268870198 Q02792 0.9439849853515624 0.0 35.67358584638083 25.0 0.0 no 13072 chrXV_421510 32878 essential YOR048C 121 - TAACTCACCGTTTGGATTTG E|46|D silent|GAG>GAA|E|46 E|46|Q E|46|K RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 -0.1293485703031814 Q02792 0.94931298494339 0.956179976463318 0.9475290179252625 0.0 0.0 0.0 44.403305960189535 40.0 0.0 no 13073 chrXV_421559r 32881 essential YOR048C 69 + GAGCAACCTCAGATAGTCGA Q|25|E Q|25|* P|26|A P|26|S RAT1 Ribonucleic Acid Trafficking 1006.0 0 0 0 0 -0.08503013174724673 Q02792 0.9590039849281312 0.9562489986419678 0.9498909711837769 1.0 0.036614734679460526 0.05312734469771385 49.060550270508884 50.0 0.0 no 13074 chrXV_430595r 32882 essential YOR056C 1009 + TTTCCGTTGACTCACGCACG S|338|C S|338|F silent|TCC>TCG|S|338 silent|TCC>TCT|S|338 NOB1 Nin1 (One) Binding protein 459.0 0 0 0 0 -1.6892612832751182 Q08444 0.945252001285553 0.9294660091400146 0.0037346703466027975 0.0019165172707289453 52.06526598195911 55.00000000000001 0.0 no 13075 chrXV_430665 32885 essential YOR056C 942 - TGCTTTGGCTTGCCGTCTTT K|320|N silent|AAG>AAA|K|320 NOB1 Nin1 (One) Binding protein 459.0 0 1 0 0 0.06063181069969845 Q08444 0.9355990290641784 0.12743805348873138 58.17461670164249 50.0 0.0 no 13076 chrXV_430783 32887 essential YOR056C 824 - TCATCTGCAACGCTACATTT M|281|I M|281|I Q|280|H silent|CAG>CAA|Q|280 NOB1 Nin1 (One) Binding protein 459.0 0 0 0 0 -0.997044599880006 Q08444 0.9553959965705872 0.9553959965705872 0.9570760130882264 1.0 1.0 0.01253662072122097 46.57894252523147 40.0 0.0 no 13077 chrXV_430787 32888 essential YOR056C 820 - CTGCAACGCTACATTTTGGA L|279|F silent|TTG>TTA|L|279 silent|GCG>GCC|A|278 silent|GCG>GCA|A|278 NOB1 Nin1 (One) Binding protein 459.0 0 0 0 0 0.03692214817397177 Q08444 0.9587849974632264 0.01964946836233139 47.078214732373 45.0 0.0 no 13078 chrXV_430883 32893 essential YOR056C 724 - TTCTACACCCAATGAACCAG E|248|Q E|248|K V|247|L V|247|I NOB1 Nin1 (One) Binding protein 459.0 0 0 0 0 0.2595222336202481 Q08444 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 46.58747376102525 45.0 0.0 no 13079 chrXV_430930 32894 essential YOR056C 677 - TTGCTTCTGTTAAGTTCTCG A|232|P A|232|T E|231|Q E|231|K NOB1 Nin1 (One) Binding protein 459.0 0 0 0 0 0.9280019536179804 Q08444 0.9573720097541808 0.9523990154266356 0.956179976463318 0.9475290179252625 0.265335351228714 0.573681652545929 0.0993836596608162 0.22930271923542025 46.70519360080301 40.0 0.0 no 13080 chrXV_430931 32895 essential YOR056C 676 - TGCTTCTGTTAAGTTCTCGG A|232|P A|232|T E|231|Q E|231|K NOB1 Nin1 (One) Binding protein 459.0 0 0 0 0 -0.9581877026516734 Q08444 0.9573720097541808 0.9523990154266356 0.956179976463318 0.9475290179252625 0.265335351228714 0.573681652545929 0.0993836596608162 0.22930271923542025 48.95826453691485 45.0 0.0 no 13081 chrXV_430965r 32896 essential YOR056C 639 + TTCGAGGATGCTGATGATGA F|214|L silent|TTC>TTT|F|214 NOB1 Nin1 (One) Binding protein 459.0 0 0 0 0 -0.3926876298130758 Q08444 0.9387490153312684 0.6152604222297668 45.62610595931813 45.0 0.0 no 13082 chrXV_431024 32898 essential YOR056C 583 - ATCATTACATATCTGCTCTT D|201|H D|201|N NOB1 Nin1 (One) Binding protein 459.0 0 0 0 0 -0.3400286052552426 Q08444 0.9486550092697144 0.956179976463318 0.11856629699468613 0.4812492430210114 43.701317118252355 30.0 0.0 no 13083 chrXV_431071 32900 essential YOR056C 536 - CAGCTTTACTCTCTAGCTCA A|185|P A|185|T NOB1 Nin1 (One) Binding protein 459.0 0 1 0 0 0.3323716115641688 Q08444 0.9573720097541808 0.9523990154266356 0.27117958664894104 0.5811784267425537 51.86839400512821 45.0 0.0 no 13084 chrXV_431256 32901 essential YOR056C 351 - GACGCATCTAATGCATCACC silent|GCG>GCC|A|123 silent|GCG>GCA|A|123 A|123|P A|123|T NOB1 Nin1 (One) Binding protein 459.0 0 0 0 1 0.2758019278326556 Q08444 0.9573720097541808 0.9523990154266356 0.2733447551727295 0.563936710357666 49.11939659401464 50.0 0.0 no 13085 chrXV_431588 32905 essential YOR056C 19 - TATCAACGCCCTTACATGTG L|12|F silent|TTG>TTA|L|12 silent|GCG>GCC|A|11 silent|GCG>GCA|A|11 NOB1 Nin1 (One) Binding protein 459.0 0 0 0 0 -0.8284690916366584 Q08444 0.9587849974632264 0.0 48.025877064660854 45.0 0.0 no 13086 chrXV_431596r 32908 essential YOR056C 8 + AAACCAAACCGCACATGTAA N|4|K silent|AAC>AAT|N|4 Q|5|E Q|5|* NOB1 Nin1 (One) Binding protein 459.0 0 1 0 0 -0.5279725978217337 Q08444 0.9439849853515624 0.9590039849281312 0.2730734646320343 1.0 41.93413796036009 40.0 0.0 no 13087 chrXV_432214r 32910 essential YOR057W 31 - CTCATCATACAAAGCTTTGT E|17|Q E|17|K D|16|H D|16|N SGT1 Suppressor of G2 (Two) allele of skp1 395.0 0 0 0 0 -0.34276367763299753 Q08446 0.1296970099210739 0.5014923810958862 0.008774198591709137 0.021547868847846985 42.34450606023131 35.0 1.0 no 13088 chrXV_432325 32911 essential YOR057W 139 + GTCTTGAAAAGCTATACTTT L|48|V L|48|F SGT1 Suppressor of G2 (Two) allele of skp1 395.0 0 0 0 0 0.7328560331291927 Q08446 0.02930426597595215 0.08029187470674515 38.672994490976464 30.0 1.0 no 13089 chrXV_432368 32912 essential YOR057W 182 + TGCAACTATGGAAAACGCAA A|62|G A|62|V T|63|S T|63|I SGT1 Suppressor of G2 (Two) allele of skp1 395.0 0 0 0 0 0.015820323874860626 Q08446 0.3103536367416382 0.1812368482351303 0.0 0.0 39.389685681961005 40.0 1.0 no 13090 chrXV_432383 32913 essential YOR057W 197 + CGCAAAGGAACTTCTTGACA A|67|G A|67|V SGT1 Suppressor of G2 (Two) allele of skp1 395.0 0 0 0 0 0.5532782127175875 Q08446 0.0659136101603508 0.02259293384850025 43.1978297669251 45.0 1.0 no 13091 chrXV_432558r 32917 essential YOR057W 375 - TCCAGACGATCTTCCCATAA silent|CTG>CTC|L|131 silent|CTG>CTA|L|131 E|132|Q E|132|K SGT1 Suppressor of G2 (Two) allele of skp1 395.0 0 0 0 0 1.0342777375506502 Q08446 0.18886643648147586 0.4720703661441803 50.137414773951775 45.0 1.0 no 13092 chrXV_432730r 32920 essential YOR057W 547 - CCAATCGATTTTAAATTTAG W|189|S W|189|* D|188|H D|188|N SGT1 Suppressor of G2 (Two) allele of skp1 395.0 0 0 0 0 0.16089696326057873 Q08446 0.0 0.006239587441086769 0.01888207346200943 34.526045327837146 25.0 1.0 no 13093 chrXV_432731r 32921 essential YOR057W 548 - ACCAATCGATTTTAAATTTA W|189|S W|189|* W|189|C W|189|* SGT1 Suppressor of G2 (Two) allele of skp1 395.0 0 0 0 0 -0.4992128224177368 Q08446 0.0 0.0 34.908527091050644 20.0 1.0 no 13094 chrXV_432982 32925 essential YOR057W 796 + GCAAAATTGATAGCACGCAA S|266|R silent|AGC>AGT|S|266 SGT1 Suppressor of G2 (Two) allele of skp1 395.0 0 0 0 0 0.3969743414582983 Q08446 0.330890029668808 41.11322550350935 40.0 1.0 no 13095 chrXV_440584r 32928 essential YOR060C 557 + AACTTTGTCCAAGCTAATTT T|187|S T|187|I 0 0 0 0 0.5233530085216804 Q08457 0.1587163507938385 0.4563174247741699 0.876800000667572 -1.1389199495315552 41.67972413429652 30.0 0.0 no 13096 chrXV_440708 32929 essential YOR060C 436 - ACTACCTTCCTTTGATACGG S|152|T S|152|N G|151|A G|151|D 0 0 0 0 -0.5217419610094147 Q08457 0.4807616770267487 0.7341176867485046 0.8608258962631226 0.30039218068122864 49.02526296562314 45.0 0.0 no 13097 chrXV_440742r 32931 essential YOR060C 399 + ACCAAATTGAAGCAAGATAT silent|ACC>ACG|T|134 silent|ACC>ACT|T|134 T|134|S T|134|I 0 0 0 0 0.3516762417400721 Q08457 0.7147828936576843 0.19207003712654114 36.75669602077238 30.0 0.0 no 13098 chrXV_440741 32932 essential YOR060C 403 - TCCAATATCTTGCTTCAATT G|141|R G|141|R G|141|A G|141|E 0 0 0 0 0.3874868713130368 Q08457 0.5066230893135071 0.5066230893135071 0.7269977927207947 1.0 43.11805011343216 30.0 0.0 no 13099 chrXV_440995r 32936 essential YOR060C 146 + TCTCGCAAAACTGCCTTTGT silent|CTC>CTG|L|50 silent|CTC>CTT|L|50 L|50|V L|50|F 0 0 0 0 -0.6182228554734923 Q08457 0.13895313441753387 0.06962644308805466 48.99112897218646 45.0 0.0 no 13100 chrXV_441083r 32937 essential YOR060C 58 + TCATTAGGGATATCCAACTT silent|GTC>GTG|V|20 silent|GTC>GTT|V|20 0 0 0 0 0.2422356111032332 Q08457 43.87714713413232 35.0 0.0 no 13101 chrXV_441123r 32939 essential YOR060C 18 + ACACTAAATTTTACTCTTAG L|8|V silent|CTA>TTA|L|8 T|7|R T|7|I 0 0 0 0 0.2410393666321093 Q08457 0.0 0.032797738909721375 0.4846898913383484 34.77997861966736 25.0 0.0 no 13102 chrXV_444814 32942 essential YOR063W 128 + AACTTCCTTCTTGGGTTACA T|44|S T|44|I S|45|C S|45|F RPL3 Ribosomal Protein of the Large subunit 387.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.3990163080339765 P14126 0.1817714273929596 0.07098215818405151 0.018627366051077843 0.08221710473299026 1.1195999383926392 0.7216000556945801 0.7289999723434448 1.6094000339508057 -1.4321999549865725 7.112599849700928 49.11416228273914 40.0 1.0 no 13103 chrXV_444849r 32945 essential YOR063W 166 - TCTGTCCAAATCTCTGACAA R|62|T R|62|K D|61|H D|61|N RPL3 Ribosomal Protein of the Large subunit 387.0 0 1 0 0 -0.460111543872684 P14126 0.18789169192314148 0.4678176939487457 0.1238187626004219 0.3109275698661804 1.1080000400543213 -0.020600000396370888 1.1754000186920166 1.357200026512146 44.68559332443578 40.0 1.0 no 13104 chrXV_444926 32947 essential YOR063W 240 + ACTCCACCAGTTGTCGTTGT P|82|A P|82|S T|81|S T|81|I RPL3 Ribosomal Protein of the Large subunit 387.0 0 0 0 0 -0.5863878369296424 P14126 0.01954742334783077 0.006481982301920652 0.07870662957429886 0.104495570063591 3.3898000717163086 4.455399990081787 -0.4891999959945679 0.5088000297546387 56.62316053200226 50.0 1.0 no 13105 chrXV_444970r 32950 essential YOR063W 287 - TCAAAGATCTCAAACCTCTT L|102|F silent|TTG>TTA|L|102 RPL3 Ribosomal Protein of the Large subunit 387.0 0 1 0 0 0.12725288853885952 P14126 0.7916349172592163 0.3531999886035919 41.11676762397707 35.0 1.0 no 13106 chrXV_445089r 32954 essential YOR063W 406 - AGCACCATCTTGAGCGTACT A|142|P A|142|T G|141|A G|141|D RPL3 Ribosomal Protein of the Large subunit 387.0 0 0 0 0 -1.8671744549593488 P14126 0.2538793087005615 0.6665179133415222 0.7542869448661804 0.6345909237861633 0.05260000005364418 0.2360000014305115 3.148200035095215 3.1396000385284424 53.373545383502744 50.0 1.0 no 13107 chrXV_445147 32955 essential YOR063W 461 + CGCTTCCGTCGTCAGAGTTT A|155|G A|155|V S|156|C S|156|F RPL3 Ribosomal Protein of the Large subunit 387.0 0 1 0 0 0.4357691975117381 P14126 0.11622276157140732 0.03703988716006279 0.047722309827804565 0.044716544449329376 -0.5839999914169312 1.399799942970276 0.05700000002980232 -0.7336000204086304 0.6078999638557434 -0.7101999521255493 56.18240893431721 55.00000000000001 1.0 no 13108 chrXV_445177 32956 essential YOR063W 491 + TCAAATCAGAAAGACTCCAT Q|165|E Q|165|* I|166|M silent|ATC>ATT|I|166 RPL3 Ribosomal Protein of the Large subunit 387.0 0 1 0 0 -1.8104316234437032 P14126 0.08075867593288423 0.6258156299591064 3.140399932861328 -0.6370000243186951 39.0361390307026 35.0 1.0 no 13109 chrXV_445245r 32958 essential YOR063W 562 - CCAGTCAACCTTTTCAGAGA W|194|S W|194|* D|193|H D|193|N RPL3 Ribosomal Protein of the Large subunit 387.0 0 1 0 0 -2.3164631709707955 P14126 0.004294705111533403 0.007582950405776502 0.08027323335409164 4.707600116729736 0.18039999902248385 -0.4142000079154968 49.54344667817173 45.0 1.0 yes 13110 chrXV_445246 32959 essential YOR063W 560 + CATCTCTGAAAAGGTTGACT I|188|M silent|ATC>ATT|I|188 S|189|C S|189|F RPL3 Ribosomal Protein of the Large subunit 387.0 0 1 0 0 -0.6537971737412062 P14126 0.11274787038564682 0.017363904044032097 0.017153900116682053 -0.2321999967098236 0.6805999875068665 -0.19339999556541446 41.53653285923365 40.0 1.0 no 13111 chrXV_445330 32960 essential YOR063W 644 + TGACGCTATTGCTGTCACCA D|216|E silent|GAC>GAT|D|216 A|217|G A|217|V RPL3 Ribosomal Protein of the Large subunit 387.0 0 0 0 0 -0.5632123655217396 P14126 0.006678866222500801 0.0003084326162934304 1.0 2.580399990081787 1.9650000333786009 -2.503000020980835 53.02648474667984 50.0 1.0 no 13112 chrXV_445331 32961 essential YOR063W 645 + GACGCTATTGCTGTCACCAA D|216|E silent|GAC>GAT|D|216 A|217|G A|217|V RPL3 Ribosomal Protein of the Large subunit 387.0 0 0 0 0 -0.32499558967079345 P14126 0.006678866222500801 0.0003084326162934304 1.0 2.580399990081787 1.9650000333786009 -2.503000020980835 51.396891972341 50.0 1.0 no 13113 chrXV_445374r 32965 essential YOR063W 691 - TTTCTTAGTACCCCATCTGT K|236|N silent|AAG>AAA|K|236 RPL3 Ribosomal Protein of the Large subunit 387.0 0 1 0 0 -2.0122204920983635 P14126 0.16150875389575958 0.19200000166893005 53.26855220978257 40.0 1.0 yes 13114 chrXV_445459r 32970 essential YOR063W 776 - TGGCAACACTCCACATAACG A|265|P A|265|T V|264|L V|264|I RPL3 Ribosomal Protein of the Large subunit 387.0 0 1 0 0 -0.830531502350104 P14126 0.0274859219789505 0.006685352418571711 0.015039419755339622 0.5067718625068665 -2.1101999282836914 5.064599990844727 -0.7797999978065491 -0.9825999736785888 46.39288809938944 50.0 1.0 no 13115 chrXV_447444 32972 high_effect YOR065W 5 + TTCAAATCTATCTAAACGTT S|3|* S|3|L 0 0 0 0 0.3991316466832421 P07143 0.3756705820560455 35.24992772769667 25.0 1.0 no 13116 chrXV_447534 32974 high_effect YOR065W 95 + TACTCAAAAGCTCGTTACAG T|33|S T|33|I Q|34|E Q|34|* 0 0 0 0 0.7154243556911865 P07143 0.6726088523864746 0.4589875340461731 1.0 0.15505999326705933 0.3724799752235413 0.17531999945640564 40.62467029435049 40.0 1.0 no 13117 chrXV_447614r 32980 high_effect YOR065W 178 - TTCAGCTGCGGTCATAGCTT E|66|Q E|66|K A|65|P A|65|T 0 0 0 0 -0.3204594428818653 P07143 0.04214958846569061 0.03311515599489212 0.03747318685054779 0.05976951867341995 0.28408798575401306 0.4684799909591675 0.21673999726772308 0.17010000348091125 1.3331199884414673 0.8212100267410278 55.201934783936174 50.0 1.0 no 13118 chrXV_447619 32981 high_effect YOR065W 180 + GCTATGACCGCAGCTGAACA A|61|G A|61|V 0 0 0 0 -0.9540662166350808 P07143 0.027256367728114128 0.02130588889122009 52.333746327373326 55.00000000000001 1.0 no 13119 chrXV_447644 32983 high_effect YOR065W 205 + TGCACGCCCCAGCATATGCT H|70|D H|70|Y H|70|Q silent|CAC>CAT|H|70 0 0 0 0 0.5563631783119929 P07143 0.12345443665981293 0.014272086322307587 0.17446114122867584 -0.06669799983501434 -0.4278660118579865 -0.4216560125350952 0.4088599979877472 0.28402000665664673 -0.05197999998927117 61.0972318466753 60.0 1.0 no 13120 chrXV_447655 32984 high_effect YOR065W 216 + GCATATGCTTGGTCCCACAA A|73|G A|73|V 0 0 0 0 0.7990809593398643 P07143 0.2944150269031525 0.19671902060508728 -0.13464400172233582 -0.043244000524282455 -0.08980000019073486 -0.11339999735355374 54.280688838575536 50.0 1.0 no 13121 chrXV_447694 32985 high_effect YOR065W 255 + GATCATGCATCCATTAGAAG H|87|D H|87|Y 0 0 0 0 -0.6489622243087416 P07143 0.016705995425581932 0.006841923110187054 1.004423975944519 1.8022600412368772 1.6731100082397459 0.9092000126838684 43.337511014838064 40.0 1.0 no 13122 chrXV_447824r 32992 high_effect YOR065W 388 - GTCATCGTATTCAAATTCTT D|136|H D|136|N D|135|H D|135|N 0 0 0 0 -0.81350146710628 P07143 0.010455679148435593 0.056407187134027474 0.10690716654062273 0.4332424700260161 0.9439539909362792 0.40222999453544617 -0.4796279966831207 -0.2599700093269348 40.995751502597564 30.0 1.0 no 13123 chrXV_447906 32994 high_effect YOR065W 467 + TGGCCCATACCCAAACGAAC silent|GGC>GGG|G|157 silent|GGC>GGT|G|157 P|158|A P|158|S 0 0 0 0 0.7937821972560406 P07143 0.0 0.0 1.4300580024719238 1.7957099676132202 50.78181022667656 55.00000000000001 1.0 no 13124 chrXV_447916r 32997 high_effect YOR065W 480 - GCTCTTGCAGCCTGTTCGTT R|166|T R|166|K A|167|P A|167|T 0 0 0 0 -0.20314248626841566 P07143 0.0 0.0 0.091014064848423 0.12787209451198578 0.6960520148277283 -0.24052999913692474 3.5389881134033203 0.7575200200080872 3.3358399868011475 -0.2073200047016144 6.0264997482299805 1.3589400053024292 60.80586484945502 55.00000000000001 1.0 no 13125 chrXV_447915r 32998 high_effect YOR065W 479 - CTCTTGCAGCCTGTTCGTTT R|166|T R|166|K A|165|P A|165|T 0 0 0 0 1.3211006291548104 P07143 0.0 0.0 0.00453909020870924 0.0030994953121989965 0.6960520148277283 -0.24052999913692474 7.398056030273437 0.4082520008087158 7.860280036926269 2.286639928817749 57.08225730047236 50.0 1.0 no 13126 chrXV_447976 33001 high_effect YOR065W 537 + ATCGTGAAAGCTAGACACGG I|180|M silent|ATC>ATT|I|180 0 0 0 0 0.009907505194344315 P07143 0.2607745826244354 0.7675279974937439 -0.6019799709320068 44.232247897961656 50.0 1.0 no 13127 chrXV_448006 33002 high_effect YOR065W 567 + TACATTTTCTCTTTGTTGAC Y|190|* silent|TAC>TAT|Y|190 0 0 0 0 0.5909559372956645 P07143 41.55588664138071 30.0 1.0 no 13128 chrXV_448030 33003 high_effect YOR065W 591 + TATCCTGATGAACCTCCTGC P|199|A P|199|S P|199|R P|199|L 0 0 0 0 0.3828399246685751 P07143 0.5207422375679016 0.41402029991149897 0.3684051632881165 0.6539795398712158 1.530661940574646 0.3997899889945984 0.7243419885635376 0.8090819716453552 52.36197752074407 50.0 1.0 no 13129 chrXV_448092r 33006 high_effect YOR065W 656 - CCATTGCAATGGAACCACCT M|225|I M|225|I A|224|P A|224|T 1 Series([], Name: modification, dtype: object) 0 0 0 -0.23898621885691 P07143 0.0 0.0 0.012068770825862885 0.07372729480266571 0.568452000617981 0.568452000617981 -2.10657000541687 1.2411240339279177 0.26688000559806824 0.26688000559806824 -0.8505399823188782 2.002219915390014 51.11917354169708 50.0 1.0 no 13130 chrXV_453972r 33012 exception YOR069W 207 - TTACCAGCCACCGACAAACC G|75|A G|75|D G|75|R G|75|S VPS5 Vacuolar Protein Sorting 675.0 0 0 0 0 0.7194736220919625 Q92331 0.4813375174999237 0.4298040270805359 0.20671114325523374 0.6629877686500549 52.031197735422154 55.00000000000001 1.0 no 13131 chrXV_454052r 33014 exception YOR069W 287 - CAGCAATCGGATCCTGTTCA A|102|P A|102|T VPS5 Vacuolar Protein Sorting 675.0 0 0 0 0 0.09655613142358596 Q92331 0.2018827199935913 0.4305976331233978 51.469599644062214 50.0 1.0 no 13132 chrXV_454152r 33016 exception YOR069W 387 - ATCGTATCGTCAAAAACTAA silent|ACG>ACC|T|135 silent|ACG>ACA|T|135 VPS5 Vacuolar Protein Sorting 675.0 0 0 0 0 0.8963540864060024 Q92331 35.619402000721834 30.0 1.0 no 13133 chrXV_454153r 33018 exception YOR069W 388 - TATCGTATCGTCAAAAACTA silent|ACG>ACC|T|135 silent|ACG>ACA|T|135 VPS5 Vacuolar Protein Sorting 675.0 0 0 0 0 0.4922629844454529 Q92331 36.29424567399696 30.0 1.0 no 13134 chrXV_454209 33020 exception YOR069W 441 + AGCATCTCTGGAAGAAGATC S|148|R silent|AGC>AGT|S|148 I|149|M silent|ATC>ATT|I|149 VPS5 Vacuolar Protein Sorting 675.0 0 0 0 0 -0.2642493944185011 Q92331 0.6274184584617615 0.158516526222229 43.9102409020868 45.0 1.0 no 13135 chrXV_454286r 33021 exception YOR069W 521 - TTCTCTTCGCTTTCAGAGAA R|180|T R|180|K K|179|N silent|AAG>AAA|K|179 VPS5 Vacuolar Protein Sorting 675.0 0 1 0 0 0.10007380875213932 Q92331 0.5819252729415894 0.942514717578888 0.479106068611145 46.978270335982295 40.0 1.0 no 13136 chrXV_454584r 33026 exception YOR069W 819 - GCCACAGCCTTTTCGGTTGG silent|GTG>GTC|V|279 silent|GTG>GTA|V|279 A|280|P A|280|T VPS5 Vacuolar Protein Sorting 675.0 0 0 0 0 -0.21723174645168108 Q92331 0.2847325801849365 0.5104486942291261 59.596197923849665 60.0 1.0 no 13137 chrXV_454654r 33027 exception YOR069W 889 - TACAGTATACTCCACATGAA V|303|L V|303|I VPS5 Vacuolar Protein Sorting 675.0 0 0 0 0 0.7835674193852361 Q92331 0.05116335675120354 0.2508785128593445 41.78788683783398 35.0 1.0 no 13138 chrXV_454754 33030 exception YOR069W 986 + TCAATTGCAGAACAACCATT Q|330|E Q|330|* VPS5 Vacuolar Protein Sorting 675.0 0 0 0 0 -0.16396646452098246 Q92331 0.0 41.32532287007774 35.0 1.0 no 13139 chrXV_454753 33032 exception YOR069W 985 + GTCAATTGCAGAACAACCAT Q|330|E Q|330|* VPS5 Vacuolar Protein Sorting 675.0 0 0 0 0 0.6880516768321033 Q92331 0.0 43.3966916845838 40.0 1.0 no 13140 chrXV_454797r 33034 exception YOR069W 1032 - CTGCCTACTGATTGCTTCTC G|350|A G|350|D G|350|R G|350|S VPS5 Vacuolar Protein Sorting 675.0 0 0 0 0 0.2176936870573769 Q92331 0.4770740866661072 0.2701578140258789 0.6101903319358826 0.35699304938316345 53.448961342496034 50.0 1.0 no 13141 chrXV_454890r 33036 exception YOR069W 1125 - TCTTTGTCCTTTTGTAGAAC D|382|H D|382|N VPS5 Vacuolar Protein Sorting 675.0 0 0 0 0 0.8896021901093836 Q92331 0.15475060045719147 0.1357167363166809 44.66659732086004 35.0 1.0 no 13142 chrXV_455126 33042 exception YOR069W 1358 + ATCACTGCCCAAGTACAACG S|454|* S|454|L L|455|V silent|CTG>TTG|L|455 VPS5 Vacuolar Protein Sorting 675.0 0 0 0 0 -0.5717988959743151 Q92331 0.02228106372058392 1.0 48.50794042704382 50.0 1.0 no 13143 chrXV_455133r 33043 exception YOR069W 1368 - TCATCTGCCTCGTTGTACTT E|463|Q E|463|K D|462|H D|462|N VPS5 Vacuolar Protein Sorting 675.0 0 0 0 0 0.020145867664668776 Q92331 0.5809645652770996 0.8944882154464722 0.0 0.0 53.52450717781363 45.0 1.0 no 13144 chrXV_455234 33044 exception YOR069W 1466 + CGACACCTCAAGAAACACCC D|490|E silent|GAC>GAT|D|490 T|491|S T|491|I VPS5 Vacuolar Protein Sorting 675.0 0 0 0 0 0.3735777535576239 Q92331 0.4868396520614624 0.5402677059173584 0.031735431402921684 47.9171125083567 55.00000000000001 1.0 no 13145 chrXV_455251r 33046 exception YOR069W 1486 - TTCTTCTGTTGATGCAGCCA E|502|Q E|502|K E|501|Q E|501|K VPS5 Vacuolar Protein Sorting 675.0 0 0 0 0 0.04126429952531513 Q92331 0.07138486951589584 0.05771822482347488 0.3923244774341583 0.5418003201484679 53.66188879945122 45.0 1.0 no 13146 chrXV_455252r 33047 exception YOR069W 1487 - ATTCTTCTGTTGATGCAGCC E|502|Q E|502|K E|501|Q E|501|K VPS5 Vacuolar Protein Sorting 675.0 0 0 0 0 0.4809128907223351 Q92331 0.07138486951589584 0.05771822482347488 0.3923244774341583 0.5418003201484679 52.340300531358594 45.0 1.0 no 13147 chrXV_466925 33049 essential YOR074C 645 - GCATATGATGCAATGTTAAA A|222|P A|222|T CDC21 Cell Division Cycle 304.0 0 0 0 0 -0.7681087814160806 P06785 0.005230571608990431 0.003695484949275851 37.83876491616519 30.0 0.0 no 13148 chrXV_466957r 33050 essential YOR074C 610 + ACCAACGTTCTTGTGATATG Q|205|E Q|205|* Y|204|* silent|TAC>TAT|Y|204 CDC21 Cell Division Cycle 304.0 0 0 0 0 -2.39369755714879 P06785 0.0 44.00852357862266 40.0 0.0 yes 13149 chrXV_466959r 33051 essential YOR074C 608 + GTACCAACGTTCTTGTGATA Y|204|* silent|TAC>TAT|Y|204 Q|205|E Q|205|* CDC21 Cell Division Cycle 304.0 0 0 0 0 -0.4243818271131671 P06785 0.0 45.962719377324454 40.0 0.0 no 13150 chrXV_467006 33053 essential YOR074C 564 - CCGGATCCTTCTCCTTCTTT G|195|R G|195|S G|193|A G|193|E CDC21 Cell Division Cycle 304.0 0 0 0 0 0.7080417606067622 P06785 0.5312241911888123 0.7414070963859558 0.6768497228622437 1.0 57.824588772732106 50.0 0.0 no 13151 chrXV_467005 33054 essential YOR074C 565 - ACCGGATCCTTCTCCTTCTT G|195|R G|195|S G|195|A G|195|D CDC21 Cell Division Cycle 304.0 0 0 0 0 0.8518260559034936 P06785 0.5312241911888123 0.7414070963859558 0.7570770382881165 0.6614263653755188 58.01962209922374 50.0 0.0 no 13152 chrXV_467325 33060 essential YOR074C 245 - TAACACCTTGCTCAGACAAT V|88|L V|88|I G|87|A G|87|D CDC21 Cell Division Cycle 304.0 0 0 0 0 0.5766327713627252 P06785 0.008617648854851723 0.2745049595832825 0.060695044696331024 0.1330515295267105 -0.7446200251579285 -0.3454999923706055 44.549656248118545 40.0 0.0 no 13153 chrXV_467363r 33062 essential YOR074C 204 + GAACTATTGTGGTTTTTGGC L|70|V silent|CTA>TTA|L|70 CDC21 Cell Division Cycle 304.0 0 0 0 0 0.4656895817760645 P06785 0.0 45.43827461312498 40.0 0.0 no 13154 chrXV_467395 33063 essential YOR074C 175 - ACCTCTAGTAAAAACCTTCT G|65|R G|65|S G|65|A G|65|D CDC21 Cell Division Cycle 304.0 0 0 0 0 -0.22583980498634754 P06785 0.01925349235534668 0.42311158776283264 0.2948139905929565 0.02277212217450142 42.79414967236761 35.0 0.0 no 13155 chrXV_467408 33065 essential YOR074C 162 - ACCTTCTTGGTCGTTAGTAG K|60|N silent|AAG>AAA|K|60 V|61|L V|61|I CDC21 Cell Division Cycle 304.0 0 0 0 0 -1.4212658612071056 P06785 0.004762277938425541 0.14776335656642914 0.08277969807386397 1.4362200498580933 50.53157522369429 45.0 0.0 no 13156 chrXV_467486 33068 essential YOR074C 84 - GTACCAGTGCCTGTTCTATC G|34|A G|34|D G|34|R G|34|S CDC21 Cell Division Cycle 304.0 0 0 0 0 0.06739397521487439 P06785 0.0037476213183254 0.08044805377721786 0.0010751237859949472 0.021970467641949654 55.610903514457156 50.0 0.0 no 13157 chrXV_468230r 33071 essential YOR075W 21 - GCAACATACTTACGGAATAT A|14|P A|14|T V|13|L V|13|I UFE1 Unknown Function Essential 346.0 0 1 0 0 -0.11754859564067575 P41834 0.977783977985382 0.9694929718971252 0.9786369800567628 0.9863060116767884 0.3029788136482239 0.6938839554786682 0.08920586109161377 0.11680328845977785 39.48313017828457 35.0 1.0 no 13158 chrXV_468391 33073 essential YOR075W 179 + GTTCCTAGTCGAATTAAACA F|61|L silent|TTC>TTT|F|61 L|62|V silent|CTA>TTA|L|62 UFE1 Unknown Function Essential 346.0 0 0 0 0 1.4421380577977252 P41834 0.9660270214080809 0.9703750014305116 0.6544925570487976 0.3374288082122803 41.159855529407075 35.0 1.0 no 13159 chrXV_468394r 33074 essential YOR075W 185 - TTACCTTGTTTAATTCGACT V|68|L V|68|I K|67|N silent|AAG>AAA|K|67 UFE1 Unknown Function Essential 346.0 0 0 0 0 0.6040315814926274 P41834 0.9786369800567628 0.9863060116767884 0.95727801322937 0.21117812395095825 0.4646747708320618 0.0833664983510971 42.273116061264545 30.0 1.0 no 13160 chrXV_468474 33076 essential YOR075W 262 + ACGAGTTTGACATGGAATGC D|88|E silent|GAC>GAT|D|88 UFE1 Unknown Function Essential 346.0 0 0 0 0 0.11233029095194366 P41834 0.9800329804420472 0.029321132227778438 43.924991238565845 45.0 1.0 no 13161 chrXV_468532r 33077 essential YOR075W 323 - TTTCCATTTCGTAATTCTCT E|114|Q E|114|K M|113|I M|113|I UFE1 Unknown Function Essential 346.0 0 0 0 0 0.5637340241752882 P41834 0.9857460260391236 0.9736970067024232 0.9849619865417479 0.9849619865417479 0.5006470680236816 0.5309935808181763 0.2022802084684372 0.2022802084684372 44.93767680920394 30.0 1.0 no 13162 chrXV_468650r 33079 essential YOR075W 441 - ACTCCATTTTCAATGTCTTG G|153|A G|153|E V|154|L V|154|I UFE1 Unknown Function Essential 346.0 0 0 0 0 0.8498642728616184 P41834 0.9656509757041932 0.9509360194206238 0.9693499803543092 0.9770190119743348 0.7545537948608398 0.27024176716804504 0.6694904565811157 0.4099515378475189 44.76257619504906 35.0 1.0 no 13163 chrXV_468694r 33080 essential YOR075W 485 - TCCACAAATTCAAACACCGT W|168|S W|168|* W|168|C W|168|* UFE1 Unknown Function Essential 346.0 0 0 0 0 -0.9779054233948544 P41834 0.9294869899749756 0.9297599792480468 0.12335096299648285 0.047365520149469376 43.542809236077005 40.0 1.0 no 13164 chrXV_468802 33081 essential YOR075W 590 + GCCTACTTTATCCAACAATG P|198|R P|198|L P|198|A P|198|S UFE1 Unknown Function Essential 346.0 0 0 0 0 1.1628552462322914 P41834 0.95032000541687 0.9589239954948424 0.9763929843902588 0.9679129719734192 0.3156994581222534 0.20999258756637573 1.0 0.9128293991088868 45.03749340122215 40.0 1.0 no 13165 chrXV_468873r 33083 essential YOR075W 664 - TTCGTCTTGTACAGTTTCTA E|228|Q E|228|K D|227|H D|227|N UFE1 Unknown Function Essential 346.0 0 0 0 0 -0.18755995239167747 P41834 0.97645902633667 0.9644089937210084 0.965224027633667 0.97645902633667 0.07104972749948503 0.06263236701488495 0.032358210533857346 0.08525906503200531 46.55259165290085 35.0 1.0 no 13166 chrXV_468913 33084 essential YOR075W 701 + GACGATATCCAAATTAACCC T|235|R T|235|M UFE1 Unknown Function Essential 346.0 0 0 0 0 0.2592709727497079 P41834 0.9528260231018066 0.9669359922409058 0.0 0.0 42.483716575394176 40.0 1.0 no 13167 chrXV_468930r 33085 essential YOR075W 721 - CAACACTTGTAGTTGCTCCT silent|GTG>GTC|V|246 silent|GTG>GTA|V|246 V|246|L V|246|M UFE1 Unknown Function Essential 346.0 0 0 0 0 -0.1210011207525741 P41834 0.9693499803543092 0.9784780144691468 0.6342594027519226 0.06903322786092758 50.39421987110251 45.0 1.0 no 13168 chrXV_471969 33093 essential YOR077W 70 + ACTACTGCCAAATATGCCAA Y|24|* silent|TAC>TAT|Y|24 Y|25|* silent|TAC>TAT|Y|25 0 0 0 0 0.5878428532840048 P40962 45.57954533799205 40.0 1.0 no 13169 chrXV_471976r 33095 essential YOR077W 80 - TACATTGCCTTTGGCATATT C|33|S C|33|Y 0 0 0 0 0.25873705780353945 P40962 0.9421560168266296 0.9290120005607604 0.0 0.0 47.56849319834095 35.0 1.0 no 13170 chrXV_471985r 33096 essential YOR077W 89 - TTGCATCTTTACATTGCCTT A|36|P A|36|T D|35|H D|35|N 0 0 0 0 0.36176617727870397 P40962 0.9573720097541808 0.9523990154266356 0.9486550092697144 0.956179976463318 0.21991829574108124 0.4127461612224579 0.0 0.0 48.88428361819194 35.0 1.0 no 13171 chrXV_472026 33097 essential YOR077W 127 + ACAAATCGCCATCTCATTTA N|43|K silent|AAC>AAT|N|43 S|45|W S|45|L 0 0 0 0 0.5109793091524469 P40962 0.9439849853515624 0.9288619756698608 0.9298099875450134 0.027930710464715958 0.0 0.0 44.05155690046514 35.0 1.0 no 13172 chrXV_472085 33098 essential YOR077W 186 + TACAATATCCAGTTTGAAAA Y|63|* silent|TAC>TAT|Y|63 0 0 0 0 1.2429294642611373 P40962 35.00173284080614 25.0 1.0 no 13173 chrXV_472110 33099 essential YOR077W 211 + TTCTACAGTTATTGAAGCAG L|72|V silent|CTA>TTA|L|72 Q|73|E Q|73|* 0 0 0 0 0.9723488782758744 P40962 0.9512209892272948 0.9590039849281312 0.39862021803855896 0.2526658475399017 40.64505590871107 35.0 1.0 no 13174 chrXV_472246r 33105 essential YOR077W 350 - CTACCTTGCCCGCGCGGCCT V|123|L V|123|I K|122|N silent|AAG>AAA|K|122 0 0 0 0 -1.0929443142420079 P40962 0.9539830088615416 0.9574310183525084 0.9355990290641784 0.341886967420578 0.695642352104187 0.3810479640960693 67.47655690889421 75.0 1.0 no 13175 chrXV_472252r 33107 essential YOR077W 356 - CCACGTCTACCTTGCCCGCG V|125|L V|125|M silent|GTG>GTC|V|125 silent|GTG>GTA|V|125 0 0 0 0 0.29004590072886594 P40962 0.9539830088615416 0.9587630033493042 0.0 0.0 62.193169113388024 70.0 1.0 no 13176 chrXV_474602r 33110 high_effect YOR080W 11 - TAGCCACGCCTGAATTCCCT A|10|P A|10|T silent|GTG>GTC|V|9 silent|GTG>GTA|V|9 0 0 0 0 0.827046957497215 Q08496 57.775979707235315 55.00000000000001 1.0 no 13177 chrXV_474815 33113 high_effect YOR080W 221 + TCCTAGATACATAAAGATAT P|75|R P|75|L P|75|A P|75|S 0 0 0 0 0.22842509838690245 Q08496 0.0 0.0 0.0 0.0 35.226517145719754 25.0 1.0 no 13178 chrXV_474816r 33114 high_effect YOR080W 225 - TCCAATATCTTTATGTATCT L|81|F silent|TTG>TTA|L|81 D|82|H D|82|N 0 0 0 0 0.11903298865367636 Q08496 0.0 0.0 0.0 40.69193152590964 25.0 1.0 no 13179 chrXV_475068 33115 high_effect YOR080W 474 + AACATGGTTCAAAAACAGGA N|159|K silent|AAC>AAT|N|159 0 0 0 0 -0.10679438193217687 Q08496 1.0 37.0068763049996 35.0 1.0 no 13180 chrXV_474984 33116 high_effect YOR080W 390 + GCATATAAAACATGTTCTCG A|131|G A|131|V 0 0 0 0 -0.5692176852258795 Q08496 0.0 0.0 38.45890878709781 35.0 1.0 no 13181 chrXV_475195r 33118 high_effect YOR080W 604 - GCCAACTAAATCAGTTTTCT G|208|R G|208|S G|208|A G|208|D 0 0 0 0 -0.7226559186710968 Q08496 0.5000880956649779 0.749649703502655 0.8235126733779907 0.5929882526397705 43.65581262361559 35.0 1.0 no 13182 chrXV_475247 33120 high_effect YOR080W 653 + ATTCCAAAGGTTTACCACTA F|219|L silent|TTC>TTT|F|219 Q|220|E Q|220|* 0 0 0 0 0.04587319507387547 Q08496 1.0 0.6238855123519897 44.838809658479526 35.0 1.0 no 13183 chrXV_475282 33121 high_effect YOR080W 688 + TGTCGCTAGTTTGTAACAAA S|231|W S|231|L L|232|V silent|CTA>TTA|L|232 0 0 0 0 -1.1942650358034814 Q08496 0.06338674575090407 0.4884355366230011 0.5001040697097778 41.22073981937189 35.0 1.0 no 13184 chrXV_475331 33124 high_effect YOR080W 737 + CTGCTTCCAAGAATTCAACT C|247|W silent|TGC>TGT|C|247 F|248|L silent|TTC>TTT|F|248 0 0 0 0 -0.028198752010309025 Q08496 0.008806457743048668 0.0 44.438933178618136 40.0 1.0 no 13185 chrXV_475448 33125 high_effect YOR080W 854 + AGTCAGTTCTAGAATCACTT silent|GTC>GTG|V|286 silent|GTC>GTT|V|286 0 0 0 0 -0.1793725735872499 Q08496 43.68706921219075 35.0 1.0 no 13186 chrXV_475562 33126 high_effect YOR080W 968 + AACACAAATCTTTAAGTTAA T|324|R T|324|I Q|325|E Q|325|* 0 0 0 0 -0.4572406792558429 Q08496 0.7100634574890137 0.4325639605522156 0.7548230886459351 31.22697014144569 20.0 1.0 no 13187 chrXV_475569 33127 high_effect YOR080W 975 + ATCTTTAAGTTAATGGTTAG I|326|M silent|ATC>ATT|I|326 0 0 0 0 1.144724888928463 Q08496 0.04666530340909958 35.57737545803826 25.0 1.0 no 13188 chrXV_475647r 33128 high_effect YOR080W 1056 - TCCAATTCATGTTGTTTATC L|358|F silent|TTG>TTA|L|358 E|359|Q E|359|K 0 0 0 0 -0.07985575484311007 Q08496 0.07535800337791443 0.4326585531234741 0.5436409115791321 42.54978761073238 30.0 1.0 no 13189 chrXV_475722 33129 high_effect YOR080W 1128 + TCACTGGTACCAATTTTCGA L|378|V silent|CTG>TTG|L|378 S|377|* S|377|L 0 0 0 0 0.4516694324356408 Q08496 0.3688870668411255 0.061655480414628976 46.38168431642139 40.0 1.0 no 13190 chrXV_475947r 33134 high_effect YOR080W 1356 - ATCGTCAGTTTCTGCAATAG silent|ACG>ACC|T|458 silent|ACG>ACA|T|458 silent|CTG>CTC|L|457 silent|CTG>CTA|L|457 0 0 0 0 0.7889211250508875 Q08496 45.13137646865936 40.0 1.0 no 13191 chrXV_476039r 33137 high_effect YOR080W 1448 - CTTCTATCCATAGTTCTTTT E|489|Q E|489|K 0 0 0 0 0.6473638719062451 Q08496 0.0 0.0 45.65024002547534 30.0 1.0 no 13192 chrXV_476156 33138 high_effect YOR080W 1562 + GCTATATCCAATTGTTAATT L|522|V silent|CTA>TTA|L|522 0 0 0 0 0.4716111328005647 Q08496 1.0 39.50418553088013 25.0 1.0 no 13193 chrXV_476163r 33140 high_effect YOR080W 1572 - TCTTCATCCAAATTAACAAT D|531|H D|531|N E|530|Q E|530|K 0 0 0 0 0.8429174128891399 Q08496 0.3081766664981842 1.0 0.3963236510753632 0.6203677654266357 36.701376079241534 25.0 1.0 no 13194 chrXV_476190r 33141 high_effect YOR080W 1599 - ACCTCGTCGTCATTCGTAAC E|539|D silent|GAG>GAA|E|539 V|540|L V|540|M 0 0 0 0 -0.7547640283412469 Q08496 0.43895262479782093 0.055290017277002335 50.287006648865315 50.0 1.0 no 13195 chrXV_476213 33142 high_effect YOR080W 1619 + GCCATCCATGCTATTTTACA P|541|R P|541|L P|541|A P|541|S 0 0 0 0 -0.36548481566741786 Q08496 51.013228604952246 40.0 1.0 no 13196 chrXV_503804 33145 essential YOR095C 505 - ATTCTTGACCCTCACGTATG K|174|N silent|AAG>AAA|K|174 RKI1 Ribose-5-phosphate Ketol-Isomerase 258.0 0 0 0 0 0.4021063058259556 Q12189 0.33677685260772705 1.7260600328445437 49.533267677381495 45.0 0.0 no 13197 chrXV_503961r 33147 essential YOR095C 345 + TTACAATTAATTAAAGGTGG Q|117|E Q|117|* RKI1 Ribose-5-phosphate Ketol-Isomerase 258.0 0 0 0 0 -0.6444478144069918 Q12189 0.02585562877357006 3.577510118484497 32.249806807216885 25.0 0.0 no 13198 chrXV_504245 33150 essential YOR095C 64 - TCTGTATGCTGCAGCTCTCT R|28|T R|28|K RKI1 Ribose-5-phosphate Ketol-Isomerase 258.0 0 0 0 0 -0.4663522576076284 Q12189 0.5090137124061584 1.0 0.2471040040254593 -0.3435879945755005 56.8181215028884 50.0 0.0 no 13199 chrXV_504258 33151 essential YOR095C 51 - GCTCTCTTGGCATCCTCCAA R|23|T R|23|K A|24|P A|24|T RKI1 Ribose-5-phosphate Ketol-Isomerase 258.0 0 1 0 0 -1.8563098314323232 Q12189 0.01475920062512159 0.6876609325408936 0.12022674083709715 0.29721829295158386 1.885241985321045 -0.2205059975385666 0.9980440139770508 1.5507160425186155 1.6126400232315063 -0.1280200034379959 59.57450505737546 55.00000000000001 0.0 no 13200 chrXV_504271r 33152 essential YOR095C 35 + ATCTTTGGGCAATCCTTTGG S|13|C S|13|F RKI1 Ribose-5-phosphate Ketol-Isomerase 258.0 0 0 0 0 0.6828788791048731 Q12189 0.030927967280149463 0.029252681881189343 50.36480302689745 45.0 0.0 no 13201 chrXV_504292 33153 essential YOR095C 17 - ATTCTAACGCATCAATTTTT E|12|Q E|12|K RKI1 Ribose-5-phosphate Ketol-Isomerase 258.0 0 0 0 0 -0.0102474527891686 Q12189 0.6721592545509338 0.9225829243659972 38.912005977059664 25.0 0.0 no 13202 chrXV_508753r 33155 essential YOR098C 2403 + TTCGGTACTGCTAACACCAA F|802|L silent|TTC>TTT|F|802 NUP1 NUclear Pore 1076.0 0 0 0 0 -0.04608398425866112 P20676 0.7848812937736511 47.3860845758922 45.0 0.0 no 13203 chrXV_508771r 33156 essential YOR098C 2385 + TCTAAATCTGCATTTTCATT S|796|C S|796|F NUP1 NUclear Pore 1076.0 0 0 0 0 -0.5432643425977319 P20676 0.021558176726102832 0.013281255029141905 39.47116150523175 25.0 0.0 no 13204 chrXV_508813 33157 essential YOR098C 2346 - TCTGTTGGCTTACCCAAGAC D|789|H D|789|N NUP1 NUclear Pore 1076.0 0 0 0 0 1.0958762001014477 P20676 0.1733851134777069 0.5150847434997559 52.039053611954394 50.0 0.0 no 13205 chrXV_508825r 33158 essential YOR098C 2331 + TCAACGCCGATTCCTGTCTT S|778|* S|778|L T|779|R T|779|M NUP1 NUclear Pore 1076.0 0 1 0 0 0.18182769087487755 P20676 0.13792701065540314 0.6446614861488342 0.11458612233400345 53.5633124413705 50.0 0.0 no 13206 chrXV_508826r 33159 essential YOR098C 2330 + CTCAACGCCGATTCCTGTCT S|778|* S|778|L T|779|R T|779|M NUP1 NUclear Pore 1076.0 0 1 0 0 -0.8315401307261521 P20676 0.13792701065540314 0.6446614861488342 0.11458612233400345 55.001070471070186 55.00000000000001 0.0 no 13207 chrXV_508962 33160 essential YOR098C 2197 - TGCTGTCGACTTCATCGACT A|739|P A|739|T silent|TCG>TCC|S|737 silent|TCG>TCA|S|737 NUP1 NUclear Pore 1076.0 0 0 0 0 1.2335217369215137 P20676 0.36402007937431335 0.5334201455116272 51.11318363859681 50.0 0.0 no 13208 chrXV_509044r 33163 essential YOR098C 2112 + CCGCCATCTTTCACCTTTGG P|706|A P|706|S P|705|R P|705|L NUP1 NUclear Pore 1076.0 0 0 0 0 0.5260975119448414 P20676 0.5937895178794861 0.35514238476753235 0.6093775629997253 0.403484970331192 57.12234375178235 55.00000000000001 0.0 no 13209 chrXV_509387r 33167 essential YOR098C 1769 + ATTCTCTTTCTCTAAGTCAG F|591|L silent|TTC>TTT|F|591 S|592|C S|592|F NUP1 NUclear Pore 1076.0 0 1 0 0 0.9533046052835906 P20676 0.0 0.0 0.0 44.022465533121874 35.0 0.0 no 13210 chrXV_509473 33169 essential YOR098C 1686 - GGCTTCTTGACTATTGTGGC K|568|N silent|AAG>AAA|K|568 K|567|N silent|AAG>AAA|K|567 NUP1 NUclear Pore 1076.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.3031194057957788 P20676 0.13376283645629886 0.5578940510749817 52.717960613934224 50.0 0.0 no 13211 chrXV_509326r 33171 essential YOR098C 1830 + AAACCCTCGTTTTCGTTTCC P|612|A P|612|S P|612|R P|612|L NUP1 NUclear Pore 1076.0 0 1 0 0 0.1905392484231228 P20676 0.0 0.0 0.0 0.0 51.28593307544156 45.0 0.0 no 13212 chrXV_509542r 33172 essential YOR098C 1614 + TCCTCTGCACAATTTACCTT silent|TCC>TCG|S|539 silent|TCC>TCT|S|539 S|539|C S|539|F NUP1 NUclear Pore 1076.0 0 0 0 1 0.3781220482702754 P20676 0.07459951192140579 0.09122182428836824 50.142192287572975 40.0 0.0 no 13213 chrXV_509661r 33173 essential YOR098C 1495 + AGTCAGAAAAGGACGCATCA S|500|* S|500|L NUP1 NUclear Pore 1076.0 0 0 0 0 -0.8073874636553929 P20676 0.5748746395111084 43.46694369987614 45.0 0.0 no 13214 chrXV_509713 33175 essential YOR098C 1446 - GTCTTGCCGAAATCGAATAA K|488|N silent|AAG>AAA|K|488 G|487|A G|487|D NUP1 NUclear Pore 1076.0 0 0 0 0 0.3854546971373752 P20676 0.3547026515007019 0.7450070977210999 0.31314370036125183 41.88036010375919 40.0 0.0 no 13215 chrXV_509905r 33177 essential YOR098C 1251 + GCCAGTCAACCTTTTAAATT silent|GCC>GCG|A|418 silent|GCC>GCT|A|418 A|418|G A|418|V NUP1 NUclear Pore 1076.0 0 0 0 1 0.4957151786041629 P20676 0.3999890685081482 0.3739570379257202 44.926736136765385 35.0 0.0 no 13216 chrXV_509996 33178 essential YOR098C 1163 - CCTTAGTTTTATTAGCCTTT K|394|N silent|AAG>AAA|K|394 NUP1 NUclear Pore 1076.0 0 0 0 0 0.6079290795333899 P20676 0.0 47.11775848134698 30.0 0.0 no 13217 chrXV_509950r 33179 essential YOR098C 1206 + ACAACTTTATTCAATTTTGG T|403|R T|403|I T|404|S T|404|I NUP1 NUclear Pore 1076.0 0 0 0 0 0.2816513061367025 P20676 0.7053614854812622 0.13812780380249026 0.6986014246940613 0.15129485726356506 36.12953446870711 25.0 0.0 no 13218 chrXV_510122r 33183 essential YOR098C 1034 + ATCTAAGAAAACTTCTCCTA S|346|C S|346|F NUP1 NUclear Pore 1076.0 0 1 0 0 0.2522839883176117 P20676 0.0 0.0 38.33195406573452 30.0 0.0 no 13219 chrXV_510106r 33184 essential YOR098C 1050 + CCTAAGGCAACTTCTTCTGC P|351|R P|351|L NUP1 NUclear Pore 1076.0 0 0 0 0 1.0126059126591107 P20676 0.582164466381073 0.4764009118080139 50.776787155460966 50.0 0.0 no 13220 chrXV_510263 33187 essential YOR098C 896 - GAACAAAGCTCTCCTGAATA V|305|L V|305|I NUP1 NUclear Pore 1076.0 0 0 0 0 0.7195973127310067 P20676 0.6171666383743286 0.5263702273368835 41.9081945256965 40.0 0.0 no 13221 chrXV_510264 33188 essential YOR098C 895 - AACAAAGCTCTCCTGAATAG V|305|L V|305|I NUP1 NUclear Pore 1076.0 0 0 0 0 0.5593632057314863 P20676 0.6171666383743286 0.5263702273368835 40.80940386461805 40.0 0.0 no 13222 chrXV_510275r 33189 essential YOR098C 881 + TGCAAAAACTGCCCCTATTC A|295|G A|295|V NUP1 NUclear Pore 1076.0 0 1 0 0 0.8560357905623082 P20676 0.3826692700386048 0.5019930005073547 47.68509826881553 45.0 0.0 no 13223 chrXV_510379 33190 essential YOR098C 780 - TCAATTTCGCTTGTCAGGTT E|267|Q E|267|K NUP1 NUclear Pore 1076.0 0 0 0 0 1.0177707322018943 P20676 0.3210215270519257 0.4246631860733032 48.69307309265293 40.0 0.0 no 13224 chrXV_510403r 33192 essential YOR098C 753 + TCAAATGGCAATCTGGCTAC S|252|* S|252|L NUP1 NUclear Pore 1076.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.3260541206339178 P20676 0.5441328883171082 44.8562994620309 45.0 0.0 no 13225 chrXV_510540 33194 essential YOR098C 619 - TTCAAAATTTGCTGACCACA E|213|Q E|213|K NUP1 NUclear Pore 1076.0 0 0 0 0 0.5713973147912873 P20676 0.060134503990411765 0.0519564263522625 41.97566808512613 35.0 0.0 no 13226 chrXV_510673 33198 essential YOR098C 486 - GTGCAAGAACCGTTTTTAAT C|168|S C|168|Y NUP1 NUclear Pore 1076.0 0 1 0 0 -0.948458357715412 P20676 1.0 0.3492207229137421 42.114612953847825 35.0 0.0 no 13227 chrXV_510682r 33201 essential YOR098C 474 + ACTCCTTCCCCTATTAAAAA P|160|A P|160|S T|159|S T|159|I NUP1 NUclear Pore 1076.0 0 1 0 0 1.2044477585084656 P20676 0.0 0.0 0.0 0.0 45.670077968539886 35.0 0.0 no 13228 chrXV_510853 33203 essential YOR098C 306 - AGTCTTTGAATGGGCAAAAT R|108|T R|108|K NUP1 NUclear Pore 1076.0 0 0 0 0 1.065769504636453 P20676 0.0 0.0 40.213043250421784 35.0 0.0 no 13229 chrXV_510901 33204 essential YOR098C 258 - TCGGTTCCATATATTATAAT E|93|Q E|93|K G|91|A G|91|E NUP1 NUclear Pore 1076.0 0 0 0 0 0.07301554124298737 P20676 0.5618500113487244 0.8715106844902039 0.3577331006526947 1.0 39.41886016507021 25.0 0.0 no 13230 chrXV_511077r 33209 essential YOR098C 79 + TCACAAACCCCAATAAAAAA T|28|R T|28|I F|27|L silent|TTC>TTT|F|27 NUP1 NUclear Pore 1076.0 0 0 0 0 0.2369839273955441 P20676 36.00144819847503 30.0 0.0 no 13231 chrXV_511123 33210 essential YOR098C 36 - AACGATCTCTTTTCGACACG silent|TCG>TCC|S|18 silent|TCG>TCA|S|18 R|17|T R|17|K NUP1 NUclear Pore 1076.0 0 0 0 1 0.1965950343718169 P20676 43.898522902374964 45.0 0.0 no 13232 chrXV_516603 33211 essential YOR103C 228 - CCCGCTAAAAACGCATTGAA silent|GCG>GCC|A|82 silent|GCG>GCA|A|82 G|83|R G|83|R OST2 OligoSaccharylTransferase 130.0 0 0 0 0 -0.6355845330604429 P46964 43.745677707808284 45.0 0.0 no 13233 chrXV_516603r 33212 essential YOR103C 225 + CCATTCAATGCGTTTTTAGC P|76|R P|76|L F|77|L silent|TTC>TTT|F|77 OST2 OligoSaccharylTransferase 130.0 0 0 0 0 0.3680673007445741 P46964 0.9387490153312684 0.0 46.9626202266694 40.0 0.0 no 13234 chrXV_516604r 33213 essential YOR103C 224 + TCCATTCAATGCGTTTTTAG P|76|R P|76|L P|76|A P|76|S OST2 OligoSaccharylTransferase 130.0 0 0 0 0 -0.17127298283052808 P46964 44.350520250069344 35.0 0.0 no 13235 chrXV_516669r 33215 essential YOR103C 159 + TGCTTCTTTTTGGTATTATT C|54|W silent|TGC>TGT|C|54 F|55|L silent|TTC>TTT|F|55 OST2 OligoSaccharylTransferase 130.0 0 0 0 0 0.8326303303203637 P46964 43.01404523768662 25.0 0.0 no 13236 chrXV_516746r 33217 essential YOR103C 82 + AAACTTTCAAGACTTCTAAG T|29|S T|29|I OST2 OligoSaccharylTransferase 130.0 0 0 0 0 -0.05595353798471514 P46964 0.9491789937019348 0.9472420215606691 0.7295804619789124 0.2077193260192871 34.685573160153524 30.0 0.0 no 13237 chrXV_528976 33220 essential YOR110W 35 + ATACAGATCCAACTGGCTTC Y|13|* silent|TAC>TAT|Y|13 TFC7 435.0 0 0 0 0 -0.7878498760659147 Q12415 47.71006080731253 45.0 1.0 no 13238 chrXV_529004 33221 essential YOR110W 63 + CCATATCCTGACCCACTTAC P|22|R P|22|L P|24|A P|24|S TFC7 435.0 0 0 0 0 -0.013141344160255973 Q12415 0.13631828129291534 0.07742483168840407 0.0730823501944542 0.034931305795907974 0.8406999707221985 1.2633600234985352 1.351140022277832 1.4257800579071045 53.08829343515333 50.0 1.0 no 13239 chrXV_529015r 33224 essential YOR110W 77 - CGCTATCAATTCCTGTAAGT S|32|T S|32|N D|31|H D|31|N TFC7 435.0 0 0 0 0 -0.3604682015076509 Q12415 0.12104996293783188 0.5765669345855713 0.04377000778913498 0.0971909910440445 1.2146199941635132 0.7093999981880188 0.5871400237083435 -0.485619992017746 46.045278505188435 40.0 1.0 no 13240 chrXV_529122r 33230 essential YOR110W 184 - TCTATAAAATGGAGAAGCGA R|68|T R|68|K TFC7 435.0 0 0 0 0 0.6767085527729576 Q12415 0.021806007251143456 0.05575224757194519 -0.9814199805259703 0.6435800194740295 36.64362595801367 35.0 1.0 no 13241 chrXV_529184 33231 essential YOR110W 243 + ATACCTGTTTATCTAGAAAG P|83|A P|83|S P|83|R P|83|L TFC7 435.0 0 0 0 0 -0.28093547974227984 Q12415 0.06314104795455933 0.06526138633489609 0.03498203679919243 0.015502939000725746 1.521299958229065 1.5662800073623655 1.1521600484848022 1.5953600406646729 37.81438865528219 30.0 1.0 no 13242 chrXV_529187r 33232 essential YOR110W 249 - ATACCCCTTTCTAGATAAAC G|89|A G|89|D G|89|R G|89|S TFC7 435.0 0 0 0 0 -0.4517825293127992 Q12415 0.0 0.0 0.0 0.0 1.2237199544906616 14.225239753723145 18.1583194732666 4.541359901428223 43.420805838891 35.0 1.0 no 13243 chrXV_529238 33233 essential YOR110W 297 + CCTGTTATTCCAGTACCTGC P|100|R P|100|L TFC7 435.0 0 0 0 0 -0.4312252164024004 Q12415 0.18963216245174408 0.10932030528783797 1.4643599987030032 1.709779977798462 55.600183675335764 50.0 1.0 no 13244 chrXV_529315 33236 essential YOR110W 374 + TACATTAACACCAAATGAAA T|126|R T|126|I TFC7 435.0 0 0 0 0 1.1995036475349472 Q12415 0.5152575969696045 0.19291432201862332 4.700220108032227 1.104300022125244 32.94927389907343 25.0 1.0 no 13245 chrXV_529316 33237 essential YOR110W 375 + ACATTAACACCAAATGAAAA T|126|R T|126|I TFC7 435.0 0 0 0 0 -0.0007928200458538133 Q12415 0.5152575969696045 0.19291432201862332 4.700220108032227 1.104300022125244 32.38477160921718 25.0 1.0 no 13246 chrXV_529415r 33238 essential YOR110W 477 - AACAGTATGCACTCAACATT silent|CTG>CTC|L|165 silent|CTG>CTA|L|165 TFC7 435.0 0 0 0 0 0.8495674567634319 Q12415 41.55816050153021 35.0 1.0 no 13247 chrXV_529448 33239 essential YOR110W 507 + GCTGCATCTAAGATTGCCCT A|170|G A|170|V A|171|G A|171|V TFC7 435.0 0 0 0 0 0.5978770642621866 Q12415 0.23058843612670896 0.011969265528023243 0.12191778421401978 0.044654659926891334 0.8235999941825867 2.2878398895263667 1.7515000104904177 0.06750000268220901 1.3473000526428225 2.124419927597046 1.6552000045776367 0.2312600016593933 54.978109254405354 50.0 1.0 no 13248 chrXV_529479 33240 essential YOR110W 538 + TGCTGGGATACGATAATCCT L|181|V silent|CTG>TTG|L|181 TFC7 435.0 0 0 0 0 0.9414718475905036 Q12415 0.026139626279473305 3.900500059127808 3.725260019302368 47.41960430265289 45.0 1.0 no 13249 chrXV_529627 33242 essential YOR110W 686 + ACCATTTAGTGACAGAAAAT P|230|R P|230|L P|230|A P|230|S TFC7 435.0 0 1 0 0 -0.1080371185908027 Q12415 0.029919834807515144 0.019589906558394432 0.07927895337343216 0.0494752861559391 1.7827399969100952 1.7201399803161619 1.5480200052261353 1.8712600469589236 37.48561597003044 30.0 1.0 no 13250 chrXV_529671r 33243 essential YOR110W 733 - TTCACCACTACTCAAAAACT E|251|Q E|251|K G|250|A G|250|D TFC7 435.0 0 0 0 0 0.3409450930308481 Q12415 0.04299474507570267 0.03904958814382553 0.0 0.0 -0.915019989013672 -1.5942399501800537 2.6619999408721924 3.03275990486145 40.21807975551428 35.0 1.0 no 13251 chrXV_529773r 33244 essential YOR110W 835 - TGCTTCTGGTATTGGTGAGC A|285|P A|285|T E|284|Q E|284|K TFC7 435.0 0 1 0 0 1.4212541339623244 Q12415 0.2692697048187256 0.5844929814338684 0.38902798295021057 0.6218513250350952 52.933681325971015 50.0 1.0 no 13252 chrXV_529786 33245 essential YOR110W 845 + ACCAGAAGCAGATGATCAAA P|283|R P|283|L P|283|A P|283|S TFC7 435.0 0 1 0 0 0.9183360775012676 Q12415 0.5177398920059204 0.2984999120235443 0.7635844349861145 0.7439168095588684 41.51838805069861 40.0 1.0 no 13253 chrXV_529826 33247 essential YOR110W 885 + ATCAGTGTTGATATTCCCAG I|296|M silent|ATC>ATT|I|296 TFC7 435.0 0 0 0 0 0.7813239326535732 Q12415 0.024984708055853844 47.9817875243686 40.0 1.0 no 13254 chrXV_529841r 33248 essential YOR110W 903 - CTCTCTTTGTAATTGCCGCT E|307|D silent|GAG>GAA|E|307 E|307|Q E|307|K TFC7 435.0 0 0 0 0 0.3281204131571599 Q12415 0.58289635181427 0.5653399825096129 0.9128634333610536 52.05825786829104 45.0 1.0 no 13255 chrXV_529842r 33250 essential YOR110W 904 - CCTCTCTTTGTAATTGCCGC E|307|D silent|GAG>GAA|E|307 R|308|T R|308|K TFC7 435.0 0 0 0 0 -0.3734719119138156 Q12415 0.58289635181427 0.3244966268539429 0.8024235367774963 53.929980078985864 50.0 1.0 no 13256 chrXV_540953 33252 essential YOR116C 3173 - TTTCACTGATTCTATAAAGT E|1064|Q E|1064|K S|1063|T S|1063|N RPO31 RNA POlymerase 1460.0 0 0 0 0 -0.13474002833882007 P04051 0.4383595883846283 0.7030560970306396 1.0 0.015231442637741566 2.125999927520752 3.407999992370605 36.853114865333055 25.0 0.0 no 13257 chrXV_540905r 33253 essential YOR116C 3218 + TGCTCTTTTCAAATATCGTA A|1074|G A|1074|V L|1075|V L|1075|F RPO31 RNA POlymerase 1460.0 0 0 0 0 0.8197190858852146 P04051 0.008125312626361847 0.01934992149472237 0.2833203375339508 0.3566482663154602 41.17747599353771 30.0 0.0 no 13258 chrXV_540979 33254 essential YOR116C 3147 - ACAGATGTTTTAACATTATC V|1056|L V|1056|I RPO31 RNA POlymerase 1460.0 0 0 0 0 0.2553818769592185 P04051 0.4722598195075989 0.3187543749809265 35.72974000306215 25.0 0.0 no 13259 chrXV_541021 33255 essential YOR116C 3105 - ATACCTTGTAATTCTTTTGC G|1041|A G|1041|D G|1041|R G|1041|S RPO31 RNA POlymerase 1460.0 0 0 0 0 0.09903316807276392 P04051 0.8115357160568237 0.7215784788131714 0.5500995516777039 0.7726253867149353 42.93319913605973 30.0 0.0 no 13260 chrXV_541066r 33256 essential YOR116C 3057 + GCTAATTTAAGAAAGTCCAG A|1020|G A|1020|V RPO31 RNA POlymerase 1460.0 0 0 0 0 -0.29754849031482866 P04051 0.3690146207809448 0.293050229549408 38.33195406573458 35.0 0.0 no 13261 chrXV_541068r 33257 essential YOR116C 3055 + TGGCTAATTTAAGAAAGTCC A|1020|G A|1020|V RPO31 RNA POlymerase 1460.0 0 0 0 0 -0.2897163476648865 P04051 0.3690146207809448 0.293050229549408 39.3236936571584 35.0 0.0 no 13262 chrXV_541105r 33258 essential YOR116C 3018 + TCCTTAAGAGAATATATTAA silent|TCC>TCG|S|1007 silent|TCC>TCT|S|1007 S|1007|C S|1007|F RPO31 RNA POlymerase 1460.0 0 0 0 0 0.6703510805436419 P04051 0.02915596589446068 0.027337001636624336 32.705375025529975 20.0 0.0 no 13263 chrXV_541235r 33259 essential YOR116C 2888 + AAACGAAATATTAGGACCAT N|964|K silent|AAC>AAT|N|964 RPO31 RNA POlymerase 1460.0 0 0 0 0 -0.42683303756283264 P04051 0.7354018092155457 35.77397750314276 30.0 0.0 no 13264 chrXV_541257 33260 essential YOR116C 2869 - TGCAGTTTCCATAATTGCAT A|963|P A|963|T RPO31 RNA POlymerase 1460.0 0 0 0 0 -0.3757321275903899 P04051 0.0654827281832695 0.5531432628631592 46.570923147125995 35.0 0.0 no 13265 chrXV_541258 33261 essential YOR116C 2868 - GCAGTTTCCATAATTGCATA A|963|P A|963|T RPO31 RNA POlymerase 1460.0 0 0 0 0 0.7015753171105681 P04051 0.0654827281832695 0.5531432628631592 46.0297471949375 35.0 0.0 no 13266 chrXV_541288r 33262 essential YOR116C 2835 + ACTTTTAATAACCAAGATAA T|946|S T|946|I RPO31 RNA POlymerase 1460.0 0 0 0 0 -0.0014762669293734154 P04051 0.4838272631168366 0.4117528796195984 32.58676612208262 20.0 0.0 no 13267 chrXV_541357 33263 essential YOR116C 2769 - GCATTACCTTCCATTTCCAG A|930|P A|930|T G|928|A G|928|D RPO31 RNA POlymerase 1460.0 0 0 0 0 -0.14678027736268434 P04051 0.18591341376304624 0.22474300861358645 0.2609238028526306 0.0025978644844144587 2.240000009536743 2.225600004196167 53.11320672614522 45.0 0.0 no 13268 chrXV_541393r 33266 essential YOR116C 2730 + ATCGTCCAATTCACATATGG I|911|M silent|ATC>ATT|I|911 silent|GTC>GTG|V|912 silent|GTC>GTT|V|912 RPO31 RNA POlymerase 1460.0 0 0 0 0 -1.0944879530286826 P04051 0.039609696716070175 -0.5257999897003174 44.71790243847364 40.0 0.0 no 13269 chrXV_541417r 33267 essential YOR116C 2706 + ACGGTCAGAACTTCAGCCAA T|903|R T|903|M silent|GTC>GTG|V|904 silent|GTC>GTT|V|904 RPO31 RNA POlymerase 1460.0 0 0 0 0 -0.8880386874002766 P04051 0.0022212620824575424 0.0012947822688147426 2.829200029373169 -1.567399978637695 49.836741335455095 50.0 0.0 no 13270 chrXV_541436r 33268 essential YOR116C 2687 + TTCTTGTCAGTATGACAATA S|897|C S|897|F RPO31 RNA POlymerase 1460.0 0 0 0 0 -0.3132452884056809 P04051 0.0870426669716835 0.022459181025624275 40.05764612265778 30.0 0.0 no 13271 chrXV_541488 33269 essential YOR116C 2638 - AGACATGTAACCAGTCTCTG M|885|I M|885|I RPO31 RNA POlymerase 1460.0 0 0 0 0 -0.9702867873556796 P04051 0.0 0.0 46.56094603095136 45.0 0.0 no 13272 chrXV_541543r 33272 essential YOR116C 2580 + TTTCTGTTCCATGCTATTTC L|862|V silent|CTG>TTG|L|862 RPO31 RNA POlymerase 1460.0 0 0 0 0 0.2500141327823777 P04051 0.07048097252845764 0.871999979019165 48.14645505083604 35.0 0.0 no 13273 chrXV_541551 33273 essential YOR116C 2575 - AGCATGGAACAGAAATTCTG A|865|P A|865|T RPO31 RNA POlymerase 1460.0 0 0 0 0 -2.3666577804955566 P04051 0.02506357058882713 0.6181235909461975 3.496999979019165 0.09800001978874208 39.605235535993984 40.0 0.0 yes 13274 chrXV_541609r 33275 essential YOR116C 2514 + TCGAAAACACCCCAATCCAA S|839|W S|839|L RPO31 RNA POlymerase 1460.0 0 0 0 0 0.5804884381292199 P04051 0.0017390254652127626 0.009527058340609074 45.9313212135325 45.0 0.0 no 13275 chrXV_541669r 33278 essential YOR116C 2454 + TCTGGTAATCGTGTTCCGGA S|819|C S|819|F RPO31 RNA POlymerase 1460.0 0 0 0 0 -0.05573137923108504 P04051 0.053866349160671234 0.031697448343038566 51.9587257596345 50.0 0.0 no 13276 chrXV_541718r 33280 essential YOR116C 2405 + CACATTAAATGTTTCACAGA T|803|R T|803|I RPO31 RNA POlymerase 1460.0 0 0 0 0 0.9098772235105086 P04051 0.5214225649833679 0.1918511539697647 -0.06340000033378601 -1.080600023269653 37.50264536668158 30.0 0.0 no 13277 chrXV_541753 33281 essential YOR116C 2373 - CCACAAGTAGCCATAATTAA C|797|S C|797|Y G|798|R G|798|S RPO31 RNA POlymerase 1460.0 0 0 0 0 -1.7683277012836336 P04051 0.5869500637054443 0.005039841402322054 0.0 0.0 41.8409457238771 35.0 0.0 no 13278 chrXV_541753r 33282 essential YOR116C 2370 + CCATTAATTATGGCTACTTG P|791|R P|791|L RPO31 RNA POlymerase 1460.0 0 0 0 0 -0.05527809805704842 P04051 0.0 0.0 3.3020000457763667 -1.0199999809265137 42.176223931673974 35.0 0.0 no 13279 chrXV_541859r 33285 essential YOR116C 2264 + TTGCAATGAAGAACAAACAT C|756|W silent|TGC>TGT|C|756 RPO31 RNA POlymerase 1460.0 0 0 0 0 0.20111388811400788 P04051 0.0026996158994734287 34.192534813036836 30.0 0.0 no 13280 chrXV_542029r 33287 essential YOR116C 2094 + AAACTATGTGCTAGGTTCTT L|700|V silent|CTA>TTA|L|700 RPO31 RNA POlymerase 1460.0 0 0 0 0 0.13725922756826553 P04051 0.09277483075857162 43.59183548313632 35.0 0.0 no 13281 chrXV_542131r 33290 essential YOR116C 1992 + GACAAGTCTGTTCTAGGTGA D|665|E silent|GAC>GAT|D|665 RPO31 RNA POlymerase 1460.0 0 0 0 0 0.3766118525783706 P04051 0.06638471782207489 47.53643002175676 45.0 0.0 no 13282 chrXV_542264 33294 essential YOR116C 1862 - CGTCTAAGTTTATCACAACT D|627|H D|627|N RPO31 RNA POlymerase 1460.0 0 0 0 0 -0.5766661450002951 P04051 0.006784038618206978 0.018045753240585327 41.08832772237804 35.0 0.0 no 13283 chrXV_542265 33295 essential YOR116C 1861 - GTCTAAGTTTATCACAACTG D|627|H D|627|N RPO31 RNA POlymerase 1460.0 0 0 0 0 0.5247199689620244 P04051 0.006784038618206978 0.018045753240585327 39.664422637600296 35.0 0.0 no 13284 chrXV_542329r 33298 essential YOR116C 1794 + AAACCGTATTACTTATGGAC P|600|A P|600|S P|600|R P|600|L RPO31 RNA POlymerase 1460.0 0 0 0 0 -5.608271470251949 P04051 0.0 0.0 0.0 0.0 39.758814601343204 35.0 0.0 yes 13285 chrXV_542489r 33300 essential YOR116C 1634 + GTCAGGTGAACCTATTATTG S|546|* S|546|L RPO31 RNA POlymerase 1460.0 0 0 0 0 -4.724999415006974 P04051 0.0013390673557296395 44.214699196647416 40.0 0.0 yes 13286 chrXV_542479 33301 essential YOR116C 1647 - TCTTGAGTAGCCGCAATAAT D|556|H D|556|N RPO31 RNA POlymerase 1460.0 0 0 0 0 -3.518856347617444 P04051 0.0 0.0 -0.8479999899864197 -2.075999975204468 45.630257795103425 40.0 0.0 yes 13287 chrXV_542506r 33302 essential YOR116C 1617 + AACTTATTAACACCTAAGTC N|540|K silent|AAC>AAT|N|540 RPO31 RNA POlymerase 1460.0 0 0 0 0 -1.040289699426183 P04051 0.0 -0.1340000033378601 37.454743050597294 30.0 0.0 no 13288 chrXV_542560 33303 essential YOR116C 1566 - GCACGAGCCTCTTCGGTTTG R|528|P R|528|H A|529|P A|529|T RPO31 RNA POlymerase 1460.0 0 0 0 0 -1.491119899333334 P04051 0.00310636218637228 0.003415560815483332 0.015490400604903696 0.5496670007705688 4.987360000610352 0.6808000206947327 2.625880002975464 -0.6640599966049194 57.0100530314964 60.0 0.0 no 13289 chrXV_542553 33304 essential YOR116C 1573 - AGCTTCTGCACGAGCCTCTT A|531|P A|531|T E|530|Q E|530|K RPO31 RNA POlymerase 1460.0 0 0 0 0 -2.5499132513035314 P04051 0.0 0.0 0.0 0.0 5.01200008392334 2.657999992370605 0.7122299671173096 0.5888999700546265 58.49499978237532 55.00000000000001 0.0 yes 13290 chrXV_542605 33306 essential YOR116C 1521 - CCGTCGAAGTCAGCGTTATA G|514|R G|514|S D|513|H D|513|N RPO31 RNA POlymerase 1460.0 0 1 0 0 -5.0365430820978005 P04051 0.0 0.0 0.03460869938135147 0.016073247417807583 5.868000030517577 4.434000015258789 0.5479999780654907 -0.1340000033378601 49.952885414043976 50.0 0.0 yes 13291 chrXV_542605r 33307 essential YOR116C 1518 + CCTTATAACGCTGACTTCGA P|507|R P|507|L RPO31 RNA POlymerase 1460.0 0 1 0 0 0.8809258917218812 P04051 0.0038748132064938545 0.013045593164861202 46.63784348738154 45.0 0.0 no 13292 chrXV_542634 33308 essential YOR116C 1492 - AACACATTCATTTAATCTAA V|504|L V|504|I C|503|S C|503|Y RPO31 RNA POlymerase 1460.0 0 0 0 0 0.0650590319776847 P04051 0.013762390241026878 0.01874559000134468 0.0 0.0 33.47144710781328 20.0 0.0 no 13293 chrXV_542854 33314 essential YOR116C 1272 - TTCGCCCCAGGATGGACATT silent|GCG>GCC|A|430 silent|GCG>GCA|A|430 A|430|P A|430|T RPO31 RNA POlymerase 1460.0 0 0 0 0 -4.04371603300393 P04051 0.0 0.0 56.67754585814504 55.00000000000001 0.0 yes 13294 chrXV_542924r 33316 essential YOR116C 1199 + AGTCTTGACGTATCCCGAAA silent|GTC>GTG|V|401 silent|GTC>GTT|V|401 RPO31 RNA POlymerase 1460.0 0 0 0 0 0.12117374756466705 P04051 47.553885355382654 45.0 0.0 no 13295 chrXV_543102 33319 essential YOR116C 1024 - TTTCACTTTTCCGCCGCCAT silent|GTG>GTC|V|347 silent|GTG>GTA|V|347 V|347|L V|347|M RPO31 RNA POlymerase 1460.0 0 0 0 0 0.5038964016178156 P04051 0.3154425621032715 0.12138960510492325 57.68386221688775 50.0 0.0 no 13296 chrXV_543115r 33321 essential YOR116C 1008 + CTACCAGGTTCATCCAATGG P|338|A P|338|S P|338|R P|338|L RPO31 RNA POlymerase 1460.0 0 0 0 0 0.13550319420409815 P04051 0.08025635033845901 0.2168376445770264 0.009353078901767729 0.009690293110907078 50.553216616371174 50.0 0.0 no 13297 chrXV_543275r 33326 essential YOR116C 848 + TGACTTGACAGTAAAGCTTA D|284|E silent|GAC>GAT|D|284 RPO31 RNA POlymerase 1460.0 0 0 0 0 0.4161980207373481 P04051 0.0 40.156906098031136 35.0 0.0 no 13298 chrXV_543339r 33328 essential YOR116C 784 + CCGCACCTCCGGTTTGTATA A|263|G A|263|V silent|CCC>CCG|P|262 silent|CCC>CCT|P|262 RPO31 RNA POlymerase 1460.0 0 0 0 0 0.23227250734989266 P04051 0.025667253881692886 1.0 57.41806154304266 55.00000000000001 0.0 no 13299 chrXV_543499 33332 essential YOR116C 627 - TTCACATAACGCTCTAGTTC silent|GTG>GTC|V|215 silent|GTG>GTA|V|215 V|215|L V|215|M RPO31 RNA POlymerase 1460.0 0 0 0 0 -0.08909855857023463 P04051 1.0 0.14328858256340027 44.69837797606447 40.0 0.0 no 13300 chrXV_543590r 33336 essential YOR116C 533 + TATCCATGATACATTTCGTT I|179|M silent|ATC>ATT|I|179 H|180|D H|180|Y RPO31 RNA POlymerase 1460.0 0 0 0 0 0.4304010073469876 P04051 0.11820601671934128 0.0061508347280323505 0.0015489797806367278 42.74915604531553 30.0 0.0 no 13301 chrXV_543587 33337 essential YOR116C 539 - CTACCCAACGAAATGTATCA V|186|L V|186|I W|185|C W|185|* RPO31 RNA POlymerase 1460.0 0 0 0 0 -0.4493580534943693 P04051 0.7800257205963135 0.4733580350875855 0.17558807134628296 42.74701164525311 40.0 0.0 no 13302 chrXV_543661r 33339 essential YOR116C 462 + CTGCATTGTGGTGCTCTTAA H|156|D H|156|Y RPO31 RNA POlymerase 1460.0 0 1 0 0 0.033690431978008466 P04051 0.2860385775566101 0.8850396871566772 50.394426592841064 45.0 0.0 no 13303 chrXV_543686 33340 essential YOR116C 440 - ACCTTCTTTGCTTTTTACAT R|153|T R|153|K R|153|S silent|AGG>AGA|R|153 RPO31 RNA POlymerase 1460.0 0 1 0 0 0.2636660790614249 P04051 0.5815116167068481 0.5866121649742126 0.6324208378791809 46.70065521276899 30.0 0.0 no 13304 chrXV_543832r 33343 essential YOR116C 291 + GCCACCATTCAAATACTGCA silent|GCC>GCG|A|98 silent|GCC>GCT|A|98 A|98|G A|98|V RPO31 RNA POlymerase 1460.0 0 0 0 1 0.474935507417911 P04051 0.3590148985385895 0.5206063389778137 2.0543668270111084 1.3143867254257202 49.4693435736951 45.0 0.0 no 13305 chrXV_543865r 33345 essential YOR116C 258 + GCTTTGCCTGTTTTCCACAT A|87|G A|87|V P|89|A P|89|S RPO31 RNA POlymerase 1460.0 0 0 0 0 1.3254970504026646 P04051 0.2778165340423584 1.0 0.014539479278028013 0.01178654469549656 56.01188781711061 45.0 0.0 no 13306 chrXV_543923r 33348 essential YOR116C 200 + TGCAACCTGTCACGGCAACT A|68|G A|68|V T|69|S T|69|I RPO31 RNA POlymerase 1460.0 0 1 0 0 1.2014940123887603 P04051 0.34659746289253235 0.2094549387693405 0.016059577465057373 0.0037025066558271646 -0.2480000257492065 3.880000114440918 52.78264682472918 55.00000000000001 0.0 no 13307 chrXV_543991r 33350 essential YOR116C 132 + GATCGTGCTCCTAAGGCGAA R|46|G R|46|C RPO31 RNA POlymerase 1460.0 0 0 0 0 0.18889437391198727 P04051 0.04457010701298714 0.0012411518255248664 51.75961427767146 55.00000000000001 0.0 no 13308 chrXV_544041 33351 essential YOR116C 85 - AGACACTTCCACTTCAGACT silent|GTG>GTC|V|34 silent|GTG>GTA|V|34 V|34|L V|34|M RPO31 RNA POlymerase 1460.0 0 0 0 0 -2.6291342708903493 P04051 0.06550916284322739 0.003379303263500333 49.453858620151145 45.0 0.0 yes 13309 chrXV_544097 33353 essential YOR116C 29 - CCAGCCCTTTAATCCTTTTC silent|CTG>CTC|L|16 silent|CTG>CTA|L|16 silent|GGG>GGC|G|15 silent|GGG>GGA|G|15 RPO31 RNA POlymerase 1460.0 0 0 0 0 -0.18442904705369628 P04051 54.22801901703747 45.0 0.0 no 13310 chrXV_544098 33355 essential YOR116C 28 - CAGCCCTTTAATCCTTTTCG silent|GGG>GGC|G|15 silent|GGG>GGA|G|15 G|15|A G|15|E RPO31 RNA POlymerase 1460.0 0 0 0 0 -0.0015662752270448473 P04051 0.7226324677467346 1.0 2.190000057220459 2.1440000534057617 51.47403946903785 45.0 0.0 no 13311 chrXV_545033r 33356 essential YOR117W 7 - AGCATCCAATTCTTCCAAGG A|9|P A|9|T D|8|H D|8|N RPT5 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 434.0 0 1 0 0 0.2845769339446207 P33297 0.9573720097541808 0.9523990154266356 0.9486550092697144 0.956179976463318 49.178693044861966 45.0 1.0 no 13312 chrXV_545183r 33358 essential YOR117W 157 - GAGCATAACGTTGTTTTCAT M|58|I M|58|I RPT5 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 434.0 0 0 0 0 -0.4551904002503593 P33297 0.9553959965705872 0.9553959965705872 0.3340049088001251 0.3340049088001251 0.6929000020027161 0.6929000020027161 43.42800297170436 35.0 1.0 no 13313 chrXV_545259 33360 essential YOR117W 230 + CCTTGTGGCTAACGTTGTCG L|78|V L|78|F RPT5 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 434.0 0 0 0 0 0.7301018382295399 P33297 0.9512209892272948 0.9587849974632264 0.07363011687994002 0.11009165644645692 0.7648666501045227 -0.1316666603088379 52.353656600468476 55.00000000000001 1.0 no 13314 chrXV_545259r 33361 essential YOR117W 233 - CCTCGACAACGTTAGCCACA E|84|Q E|84|K E|84|D silent|GAG>GAA|E|84 RPT5 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 434.0 0 0 0 0 0.3864747256820823 P33297 0.956179976463318 0.9475290179252625 0.94931298494339 0.010674603283405304 0.008430474437773228 0.12632635235786438 -0.055899977684021 -0.8345999717712402 1.353600025177002 52.31645437767668 55.00000000000001 1.0 no 13315 chrXV_545347 33363 essential YOR117W 318 + AACTTAGATAACACCGCTGT N|107|K silent|AAC>AAT|N|107 RPT5 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 434.0 0 0 0 0 -0.0672153914193489 P33297 0.9439849853515624 0.37663534283638 44.167355515813256 40.0 1.0 no 13316 chrXV_545400 33364 essential YOR117W 371 + ACAGACTGTTTTCTTGCCCA Q|125|E Q|125|* T|126|S T|126|I RPT5 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 434.0 0 0 0 0 0.26062477085361485 P33297 0.9590039849281312 0.9491789937019348 0.9472420215606691 0.9392365813255309 0.5542410016059875 0.19966429471969604 0.060600001364946365 -0.8023999929428101 0.4745999872684479 53.74292811854672 45.0 1.0 no 13317 chrXV_545437r 33366 essential YOR117W 411 - TCATTTGGCTTAAGTTTATC D|144|H D|144|N RPT5 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 434.0 0 1 0 0 0.7003256515047493 P33297 0.9486550092697144 0.956179976463318 0.06739402562379837 0.3394125998020172 41.43723242422124 30.0 1.0 no 13318 chrXV_545460r 33367 essential YOR117W 434 - AGTCTTTATTCACACCTACC D|151|H D|151|N RPT5 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 434.0 0 1 0 0 -1.2950988470773614 P33297 0.9486550092697144 0.956179976463318 0.08772343397140503 0.1555459350347519 0.090999998152256 0.0004000067710876465 48.91899483704725 40.0 1.0 no 13319 chrXV_545520 33369 essential YOR117W 491 + TTCTCGTGTAAAAGCTATGG S|165|C S|165|F R|166|G R|166|C RPT5 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 434.0 0 0 0 0 -2.2813224955236358 P33297 0.945252001285553 0.9294660091400146 0.8994590044021606 0.8926740288734436 0.178328275680542 0.7106384634971619 0.008182413876056671 0.008111131377518177 1.7294000387191772 2.0146000385284424 2.0096666812896733 1.0822000503540041 41.857745588007326 40.0 1.0 yes 13320 chrXV_545554r 33370 essential YOR117W 528 - ACGTCCGAGTAAGTTTCTGT V|183|L V|183|M D|182|H D|182|N RPT5 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 434.0 0 1 0 0 0.3452295124867869 P33297 0.9539830088615416 0.9587630033493042 0.9486550092697144 0.956179976463318 0.09030435979366302 0.003292507259175181 0.006451842375099659 0.032934077084064484 0.6118800044059753 0.6187199950218201 -1.8911999464035036 0.16220000386238098 49.717839565450106 45.0 1.0 no 13321 chrXV_545556 33372 essential YOR117W 527 + CACAGAAACTTACTCGGACG T|177|R T|177|I RPT5 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 434.0 0 1 0 0 0.14518706274825674 P33297 0.9476869702339172 0.9472420215606691 0.17624327540397644 0.06515471637248993 42.49726267932846 50.0 1.0 no 13322 chrXV_545637 33377 essential YOR117W 608 + TGCAGATAAATTCAAAGATA A|204|G A|204|V RPT5 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 434.0 0 1 0 0 -0.3821253054549605 P33297 0.9484469890594482 0.9504740238189696 0.08024817705154419 0.1076737493276596 0.6430000066757202 0.6603999733924866 32.91743397952132 25.0 1.0 no 13323 chrXV_545671r 33380 essential YOR117W 645 - CCGTACATTAGGGCACCCTT G|222|R G|222|R M|220|I M|220|I RPT5 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 434.0 0 0 0 0 -5.5651326355976645 P33297 0.941340982913971 0.941340982913971 0.9553959965705872 0.9553959965705872 0.0 0.0 0.024399716407060627 0.024399716407060627 9.607159614562988 9.607159614562988 57.07622278459394 55.00000000000001 1.0 yes 13324 chrXV_545782 33383 essential YOR117W 753 + GTACAAATGTATATCGGTGA Q|253|E Q|253|* RPT5 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 434.0 0 0 0 0 -0.07890133464015632 P33297 0.9590039849281312 0.014791917987167837 0.6929866671562195 39.76714299318553 35.0 1.0 no 13325 chrXV_545814 33384 essential YOR117W 785 + AGTCCGCGATGCTTTTGCAC silent|GTC>GTG|V|263 silent|GTC>GTT|V|263 R|264|G R|264|C RPT5 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 434.0 0 0 0 0 -0.15096883582871667 P33297 0.8994590044021606 0.8926740288734436 0.007903230376541616 0.0010774960974231362 1.2510067224502563 0.917519986629486 55.32819798914687 55.00000000000001 1.0 no 13326 chrXV_545882r 33387 essential YOR117W 856 - ATCAAATCTCTTAGTACCAA D|292|H D|292|N RPT5 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 434.0 0 1 0 0 0.03973579758821518 P33297 0.9486550092697144 0.956179976463318 0.011442089453339577 0.1846286952495575 0.7206532955169678 0.3298799991607666 39.96478175329838 30.0 1.0 no 13327 chrXV_545904 33388 essential YOR117W 875 + TTCTGAAAAATCCGGTGATA S|293|C S|293|F RPT5 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 434.0 0 1 0 0 0.19846508964150514 P33297 0.945252001285553 0.9294660091400146 0.007594793103635311 0.0032561637926846747 0.15323001146316528 0.7015799880027771 39.55851690434729 35.0 1.0 no 13328 chrXV_545915r 33389 essential YOR117W 889 - TCTTTGCACTTCCCTATCAC R|303|T R|303|K silent|GTG>GTC|V|301 silent|GTG>GTA|V|301 RPT5 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 434.0 0 0 0 0 1.142050392772311 P33297 0.932735025882721 0.955805003643036 0.00347255845554173 0.021306559443473816 0.4942600131034851 0.3713200092315674 1.1698533296585083 0.1643066555261612 52.99574634896766 45.0 1.0 no 13329 chrXV_545943 33391 essential YOR117W 914 + GCTGGAATTATTGAATCAAT L|306|V silent|CTG>TTG|L|306 RPT5 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 434.0 0 0 0 0 0.9334930901171185 P33297 0.9512209892272948 0.06608667969703674 0.7766000032424927 2.5305800437927246 37.564911578325855 30.0 1.0 no 13330 chrXV_549180r 33392 essential YOR119C 1044 + CTGCATTTAGTTAGATCATT H|350|D H|350|Y 0 1 0 0 -0.20116777550189124 Q12196 0.9473130106925964 0.9489949941635132 0.00986617524176836 1.0 41.921147258162186 30.0 0.0 no 13331 chrXV_549260 33394 essential YOR119C 967 - ACTAGCAATGTATGCAACCA S|329|T S|329|N A|328|P A|328|T 0 0 0 0 0.15547717224359522 Q12196 0.9512869715690612 0.9536849856376648 0.9573720097541808 0.9523990154266356 0.5738694071769714 0.4625821709632874 0.22794777154922485 0.4419775903224945 45.40623061218832 40.0 0.0 no 13332 chrXV_549448r 33396 essential YOR119C 776 + GATCGATGTTTCCCAAAGTG I|260|M silent|ATC>ATT|I|260 0 0 0 0 0.2913742337154598 Q12196 0.9598389863967896 0.006890102289617062 46.32286365758843 45.0 0.0 no 13333 chrXV_549562r 33398 essential YOR119C 662 + CCATTATTATCACACAATGG H|222|D H|222|Y 0 0 0 0 0.4261217763854316 Q12196 0.9473130106925964 0.9489949941635132 0.3963797092437744 0.02796761877834797 40.66809534485435 35.0 0.0 no 13334 chrXV_549565r 33399 essential YOR119C 659 + TTTCCATTATTATCACACAA F|221|L silent|TTC>TTT|F|221 H|222|D H|222|Y 0 0 0 0 0.2739681838365068 Q12196 0.9387490153312684 0.9473130106925964 0.9489949941635132 0.773084819316864 0.3963797092437744 0.02796761877834797 39.684503027729995 25.0 0.0 no 13335 chrXV_549678 33400 essential YOR119C 549 - TTCTTAACTTCTATTGGCTT K|189|N silent|AAG>AAA|K|189 0 0 0 0 0.08141135459345232 Q12196 0.9355990290641784 0.0077025224454700955 43.5890414447141 30.0 0.0 no 13336 chrXV_549776r 33403 essential YOR119C 448 + CCAGATCTCAACATAATCCA silent|TCC>TCG|S|150 silent|TCC>TCT|S|150 S|152|C S|152|F 0 0 0 0 0.2907937969757013 Q12196 0.945252001285553 0.9294660091400146 0.00678972527384758 0.005747164133936167 45.02053204272625 40.0 0.0 no 13337 chrXV_549832 33404 essential YOR119C 395 - TTTCACGATCTTTGAAGACT E|138|Q E|138|K R|137|P R|137|H 0 0 0 0 0.4554115556552575 Q12196 0.956179976463318 0.9475290179252625 0.9099509716033936 0.9570810198783876 0.02306325547397137 0.0835869163274765 0.0 0.0 41.51485493029486 35.0 0.0 no 13338 chrXV_549839 33405 essential YOR119C 388 - ATCTTTGAAGACTAGGATAG D|136|H D|136|N 0 0 0 0 -1.205651687752531 Q12196 0.9486550092697144 0.956179976463318 0.0 0.0 38.209779726084435 35.0 0.0 no 13339 chrXV_549871 33406 essential YOR119C 356 - TCTTAATGGCATATTCTGCA K|125|N silent|AAG>AAA|K|125 0 0 0 0 -0.6158585865777619 Q12196 0.9355990290641784 0.0 45.03794314424732 35.0 0.0 no 13340 chrXV_549923 33407 essential YOR119C 304 - GCCTGTTTCCTCATCTATTA G|108|R G|108|S G|108|A G|108|D 0 0 0 0 0.02755673282557486 Q12196 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 52.9519146350317 40.0 0.0 no 13341 chrXV_549924 33408 essential YOR119C 303 - CCTGTTTCCTCATCTATTAC G|108|R G|108|S 0 0 0 0 0.934445489132697 Q12196 0.941340982913971 0.951104998588562 49.507497071251116 40.0 0.0 no 13342 chrXV_550047 33412 essential YOR119C 180 - TTCAAAAATCTCATAGTTCT L|66|F silent|TTG>TTA|L|66 0 0 0 0 0.8568275230737918 Q12196 0.9587849974632264 0.0 35.92386095396387 25.0 0.0 no 13343 chrXV_550094r 33413 essential YOR119C 130 + CATCAAAGGATAAAGCAAAT S|45|* S|45|L 0 0 0 0 -4.172476240772622 Q12196 0.9298099875450134 0.3797774612903595 33.310336892925356 30.0 0.0 yes 13344 chrXV_552422r 33415 essential YOR122C 234 + TACGGTAGACATGATGCTGA Y|79|* silent|TAC>TAT|Y|79 PFY1 ProFilin of Yeast 126.0 0 1 0 0 -0.4257868888574906 P07274 45.600750073282775 45.0 0.0 no 13345 chrXV_552440r 33417 essential YOR122C 216 + GCTGACGATAGAAGTATCTA A|73|G A|73|V D|74|E silent|GAC>GAT|D|74 PFY1 ProFilin of Yeast 126.0 0 1 0 0 -0.7700888380951241 P07274 0.04772409051656723 0.32790908217430115 0.6361703276634216 0.9699900150299072 -0.6774979829788208 3.223330020904541 1.3834199905395508 -0.29506000876426697 42.25293180717125 40.0 0.0 no 13346 chrXV_552485r 33418 essential YOR122C 171 + AGCAATGGTTTGCATATTCA S|58|R silent|AGC>AGT|S|58 PFY1 ProFilin of Yeast 126.0 0 0 0 0 -0.4372839464538267 P07274 0.04211841151118279 -0.4441680014133453 45.12917873456415 35.0 0.0 no 13347 chrXV_552500 33419 essential YOR122C 159 - CCATTGCTTTGCAAACCAGC G|60|R G|60|S S|58|T S|58|N PFY1 ProFilin of Yeast 126.0 0 0 0 0 0.16636277171263927 P07274 0.0 0.0 0.1099475845694542 0.04143674671649933 2.951162099838257 3.962203979492188 -0.4180780053138733 -0.07735399901866913 51.4264478962241 50.0 0.0 no 13348 chrXV_552500r 33420 essential YOR122C 156 + CCAGCTGGTTTGCAAAGCAA P|53|R P|53|L A|54|G A|54|V PFY1 ProFilin of Yeast 126.0 0 0 0 0 -0.5711444555183012 P07274 0.031041594222188 0.027291009202599525 0.49653160572052 0.20296962559223172 1.5960979461669922 0.79026198387146 0.7462459802627563 0.3446840047836304 0.781000018119812 0.4896200001239777 50.486941391475504 50.0 0.0 no 13349 chrXV_552539 33421 essential YOR122C 120 - ACAATTTCACCAATTTCGTT V|47|L V|47|I PFY1 ProFilin of Yeast 126.0 0 0 0 0 0.9491769586117909 P07274 0.2367197573184967 0.33460384607315063 0.06616999953985214 0.17250999808311462 42.02019202564271 30.0 0.0 no 13350 chrXV_552548r 33422 essential YOR122C 108 + TCTTTGCAACCAAACGAAAT S|37|C S|37|F Q|39|E Q|39|* PFY1 ProFilin of Yeast 126.0 0 0 0 0 -0.8337768104326992 P07274 0.06608636677265167 0.058754488825798035 0.6157932281494141 0.263839989900589 -0.28923800587654114 0.2596459984779358 39.26319523751971 35.0 0.0 no 13351 chrXV_552552 33423 essential YOR122C 107 - TTTCGTTTGGTTGCAAAGAT E|42|Q E|42|K PFY1 ProFilin of Yeast 126.0 0 0 0 0 -1.05879594276234 P07274 0.0 0.0 2.694983959197998 2.309351921081543 43.38134894283473 35.0 0.0 no 13352 chrXV_552602r 33426 essential YOR122C 54 + GCTGTCATCTACTCGAGAGC A|19|G A|19|V silent|GTC>GTG|V|20 silent|GTC>GTT|V|20 PFY1 ProFilin of Yeast 126.0 0 1 0 0 -0.3937880064994773 P07274 0.21632350981235504 0.010489193722605705 1.7132480144500732 -1.5520800352096558 1.4819999933242798 -1.381160020828247 53.007126585056646 55.00000000000001 0.0 no 13353 chrXV_552619 33427 essential YOR122C 40 - GACAGCTTTGTCGACTTTAC V|20|L V|20|I A|19|P A|19|T PFY1 ProFilin of Yeast 126.0 0 1 0 0 -0.7248402535348741 P07274 0.013937653973698616 0.0176596250385046 0.016118500381708145 0.0112317381426692 -0.1664620041847229 0.36423999071121216 3.3182621002197266 -0.4746499955654144 4.754119873046875 -0.3335399925708771 46.944218585140284 45.0 0.0 no 13354 chrXV_564963 33430 exception YOR128C 1209 - CCCATGATGATTCCAACCAA M|409|I M|409|I G|410|R G|410|R ADE2 ADEnine requiring 571.0 0 0 0 0 0.20021934652161613 P21264 0.9553959965705872 0.9553959965705872 0.941340982913971 0.941340982913971 0.0 0.0 0.0 0.0 2.341586112976074 2.341586112976074 49.01727127125594 45.0 0.0 no 13355 chrXV_564963r 33431 exception YOR128C 1206 + CCATTGGTTGGAATCATCAT P|403|R P|403|L ADE2 ADEnine requiring 571.0 0 0 0 0 -0.9766828761670899 P21264 0.9432820081710817 0.9430609941482544 0.0031921949703246355 0.004084328655153513 46.45075499582794 40.0 0.0 no 13356 chrXV_565073 33434 exception YOR128C 1099 - TTCACATTCCGCCATACTGG E|373|Q E|373|K C|372|S C|372|Y ADE2 ADEnine requiring 571.0 0 0 0 0 0.04805131662575421 P21264 0.956179976463318 0.9475290179252625 0.9421560168266296 0.9290120005607604 0.4657490849494934 0.7988333702087402 0.030243227258324627 0.012699397280812263 52.41105410312849 50.0 0.0 no 13357 chrXV_565113r 33435 exception YOR128C 1056 + TCTAGACCTAACAGAAAAGT S|353|C S|353|F P|355|A P|355|S ADE2 ADEnine requiring 571.0 0 0 0 0 -1.0846561816991382 P21264 0.945252001285553 0.9294660091400146 0.9562489986419678 0.9498909711837769 0.1299101710319519 0.2973604500293732 0.07200216501951218 0.05922222882509232 38.15390736287424 35.0 0.0 no 13358 chrXV_565223 33436 exception YOR128C 949 - TCCAAGAACATTTAGCATAA G|323|R G|323|R G|323|A G|323|E ADE2 ADEnine requiring 571.0 0 0 0 0 -0.4491249072744343 P21264 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.0 0.0 0.0 0.0 38.62944626558897 30.0 0.0 no 13359 chrXV_565224r 33437 exception YOR128C 945 + GCCATTATGCTAAATGTTCT silent|GCC>GCG|A|316 silent|GCC>GCT|A|316 A|316|G A|316|V ADE2 ADEnine requiring 571.0 0 0 0 0 0.8694978308739637 P21264 0.9484469890594482 0.9504740238189696 0.017948543652892113 0.007740697357803583 45.1700981608783 35.0 0.0 no 13360 chrXV_565297r 33438 exception YOR128C 872 + AGCTCATTTGAGATCAATAT A|292|G A|292|V H|293|D H|293|Y ADE2 ADEnine requiring 571.0 0 0 0 0 -0.3243078247627952 P21264 0.9484469890594482 0.9504740238189696 0.9473130106925964 0.9489949941635132 0.8863615393638611 0.20194190740585327 0.01324272807687521 0.00290069286711514 40.14138196243653 30.0 0.0 no 13361 chrXV_565427 33440 exception YOR128C 745 - CACACCAAATATACCACAAC V|255|L V|255|M G|254|A G|254|D ADE2 ADEnine requiring 571.0 0 0 0 0 -0.2758940070324081 P21264 0.9539830088615416 0.9587630033493042 0.9499930143356324 0.9446240067481996 0.0 0.0 0.4721271693706513 0.004838249180465937 40.57974056243097 40.0 0.0 no 13362 chrXV_565440r 33442 exception YOR128C 729 + ATCAAATCTTTTCCCGGTTG I|244|M silent|ATC>ATT|I|244 ADE2 ADEnine requiring 571.0 0 0 0 0 0.21634194446906227 P21264 0.9598389863967896 0.006293733138591051 47.01196588182973 40.0 0.0 no 13363 chrXV_565474r 33443 exception YOR128C 695 + TCAACTTAAGGCGAAGTTGT Q|233|E Q|233|* L|234|V L|234|F ADE2 ADEnine requiring 571.0 0 0 0 0 -0.3550151132188373 P21264 0.9590039849281312 0.9512209892272948 0.9587849974632264 1.0 0.2748635709285736 0.06461313366889954 42.897512728574206 40.0 0.0 no 13364 chrXV_565478 33444 exception YOR128C 694 - CAACTTCGCCTTAAGTTGAA K|237|N silent|AAG>AAA|K|237 silent|GCG>GCC|A|236 silent|GCG>GCA|A|236 ADE2 ADEnine requiring 571.0 0 0 0 0 0.5687104290251312 P21264 0.9355990290641784 0.4754059910774231 43.84016056078855 40.0 0.0 no 13365 chrXV_565486r 33445 exception YOR128C 683 + TCCGGACTCCGTTCAACTTA P|229|R P|229|L P|229|A P|229|S ADE2 ADEnine requiring 571.0 0 0 0 0 0.4161428915744991 P21264 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.2662477791309357 0.15305852890014648 0.6091099381446838 1.0 52.27782256822337 50.0 0.0 no 13366 chrXV_565531 33448 exception YOR128C 641 - AGTCACAAATATTGTCCTTG D|220|H D|220|N C|219|S C|219|Y ADE2 ADEnine requiring 571.0 0 0 0 0 0.6855475923153667 P21264 0.9486550092697144 0.956179976463318 0.9421560168266296 0.9290120005607604 1.0 0.0760030597448349 0.03281064331531525 0.002322580432519317 41.92912570932555 35.0 0.0 no 13367 chrXV_565611 33449 exception YOR128C 561 - ACTGCTAATTCTTTAGTAAA V|194|L V|194|I A|193|P A|193|T ADE2 ADEnine requiring 571.0 0 0 0 0 0.3030288443779343 P21264 0.9539830088615416 0.9574310183525084 0.9573720097541808 0.9523990154266356 0.0 0.0 0.010457034222781658 0.010231271386146544 36.92164457771565 25.0 0.0 no 13368 chrXV_565636r 33450 exception YOR128C 533 + TCCTTTGTACGCCGAAAAAT P|179|R P|179|L P|179|A P|179|S ADE2 ADEnine requiring 571.0 0 0 0 0 -0.30769489096321034 P21264 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.5281243324279785 0.3152082860469818 0.7564198970794678 0.751266598701477 43.97830402353146 40.0 0.0 no 13369 chrXV_565665 33451 exception YOR128C 507 - TTCAGTACTTCCAAAGCTTC silent|CTG>CTC|L|175 silent|CTG>CTA|L|175 ADE2 ADEnine requiring 571.0 0 0 0 0 0.7803964218561533 P21264 46.282882443741805 40.0 0.0 no 13370 chrXV_565696r 33452 exception YOR128C 473 + TAACTTCGTTGTAAAGAATA N|159|K silent|AAC>AAT|N|159 F|160|L silent|TTC>TTT|F|160 ADE2 ADEnine requiring 571.0 0 0 0 0 0.21384320717437666 P21264 0.9439849853515624 0.9387490153312684 0.0 0.4208779931068421 33.533678160536226 25.0 0.0 no 13371 chrXV_565771 33456 exception YOR128C 401 - AATCTCTTCCAACATTCAAT D|140|H D|140|N R|139|T R|139|K ADE2 ADEnine requiring 571.0 0 0 0 0 0.8984095864697755 P21264 0.9486550092697144 0.956179976463318 0.932735025882721 0.955805003643036 0.11640483140945435 0.4676454961299896 0.1930261552333832 0.8265253901481628 41.08398104335811 30.0 0.0 no 13372 chrXV_565772 33457 exception YOR128C 400 - ATCTCTTCCAACATTCAATA D|140|H D|140|N R|139|T R|139|K ADE2 ADEnine requiring 571.0 0 0 0 0 0.09331659406475099 P21264 0.9486550092697144 0.956179976463318 0.932735025882721 0.955805003643036 0.11640483140945435 0.4676454961299896 0.1930261552333832 0.8265253901481628 41.958413822093185 30.0 0.0 no 13373 chrXV_565784 33458 exception YOR128C 388 - ATTCAATAGGGACGTCTCAC L|135|F silent|TTG>TTA|L|135 ADE2 ADEnine requiring 571.0 0 0 0 0 0.29529955230484384 P21264 0.9587849974632264 0.062404371798038476 45.52617447954873 45.0 0.0 no 13374 chrXV_565797 33459 exception YOR128C 375 - GTCTCACTGGCTTGTTCCAC E|131|D silent|GAG>GAA|E|131 E|131|Q E|131|K ADE2 ADEnine requiring 571.0 0 0 0 0 -0.012240838523605607 P21264 0.94931298494339 0.956179976463318 0.9475290179252625 0.6196836233139038 0.5968257784843445 0.9187764525413512 57.741686548385296 55.00000000000001 0.0 no 13375 chrXV_566040r 33462 exception YOR128C 129 + AACTCCAATGACCACGTTAA N|44|K silent|AAC>AAT|N|44 S|45|C S|45|F ADE2 ADEnine requiring 571.0 0 0 0 0 -0.5943092584452173 P21264 0.9439849853515624 0.945252001285553 0.9294660091400146 0.4455914497375488 0.11483678221702576 0.310281366109848 -0.9715999960899352 0.7630000114440918 1.4356000423431396 43.86494853142296 40.0 0.0 no 13376 chrXV_566104r 33463 exception YOR128C 65 + AAACAGGCTCAACATTAAGA N|23|K silent|AAC>AAT|N|23 ADE2 ADEnine requiring 571.0 0 0 0 0 -0.11764804572077775 P21264 0.9439849853515624 0.32975608110427856 0.3393999934196472 38.28956342938568 35.0 0.0 no 13377 chrXV_566159r 33466 exception YOR128C 10 + GAACAGTTGGTATATTAGGA T|5|R T|5|I ADE2 ADEnine requiring 571.0 0 0 0 0 0.93158393898522 P21264 0.9476869702339172 0.9472420215606691 0.040333922952413566 0.5409238934516907 40.556531068453296 35.0 0.0 no 13378 chrXV_573256 33469 exception YOR132W 81 + CCTGCTGCAACAACCACAGA P|28|R P|28|L A|29|G A|29|V VPS17 Vacuolar Protein Sorting 551.0 0 0 0 0 0.9340795949509432 P32913 0.6562758088111877 0.7357318997383118 0.3834590017795563 0.2999044954776764 52.02841045009984 55.00000000000001 1.0 no 13379 chrXV_573315 33472 exception YOR132W 140 + GCAAACTGCAGCTTCCGTTC Q|48|E Q|48|* T|49|S T|49|I VPS17 Vacuolar Protein Sorting 551.0 0 0 0 0 0.5355553664723326 P32913 0.78298419713974 0.8395555019378662 0.17643298208713531 53.81464936930047 55.00000000000001 1.0 no 13380 chrXV_573322 33473 exception YOR132W 147 + GCAGCTTCCGTTCAGGACAA A|50|G A|50|V A|51|G A|51|V VPS17 Vacuolar Protein Sorting 551.0 0 0 0 0 0.14601909644390285 P32913 0.38003912568092346 0.2983042597770691 0.35819438099861145 0.32556775212287903 55.011861916197795 55.00000000000001 1.0 no 13381 chrXV_573329r 33474 exception YOR132W 157 - TGCAGTTCCGTTGTCCTGAA A|59|P A|59|T VPS17 Vacuolar Protein Sorting 551.0 0 0 0 0 0.7880306949438406 P32913 0.2902685105800629 0.5559213161468506 54.777396205628 50.0 1.0 no 13382 chrXV_573493 33476 exception YOR132W 318 + ACTCTACTTGCAAAAGTAAC L|108|V silent|CTA>TTA|L|108 T|107|S T|107|I VPS17 Vacuolar Protein Sorting 551.0 0 0 0 0 -1.895055004632601 P32913 0.27192121744155884 0.4507827758789063 0.09541183710098268 37.865643198217704 35.0 1.0 no 13383 chrXV_573520 33478 exception YOR132W 345 + GAACGATTTGGATCTGCAAC R|117|G R|117|* VPS17 Vacuolar Protein Sorting 551.0 0 0 0 0 -0.2677619586367003 P32913 0.0 42.72410287040361 45.0 1.0 no 13384 chrXV_573556r 33479 exception YOR132W 384 - GAGCAATCAAATATAATAGT C|134|S C|134|Y VPS17 Vacuolar Protein Sorting 551.0 0 0 0 0 -0.3792189961635064 P32913 0.019385313615202904 0.00750716356560588 33.14181472830563 25.0 1.0 no 13385 chrXV_573642r 33481 exception YOR132W 470 - TCAGATATTTGAACAATTGG silent|CTG>CTC|L|163 silent|CTG>CTA|L|163 VPS17 Vacuolar Protein Sorting 551.0 0 0 0 0 0.10115094634986684 P32913 35.64848066145112 30.0 1.0 no 13386 chrXV_573752 33485 exception YOR132W 577 + TAACGCGAAATTTCCAACTT T|194|R T|194|M R|195|G R|195|* VPS17 Vacuolar Protein Sorting 551.0 0 0 0 0 0.036824293577588166 P32913 0.06619470566511154 0.15945005416870114 0.4160822331905365 40.262788204414456 35.0 1.0 no 13387 chrXV_573797r 33486 exception YOR132W 625 - TTCTTCATTCCGAATAATTA E|215|Q E|215|K E|214|Q E|214|K VPS17 Vacuolar Protein Sorting 551.0 0 0 0 0 1.2332389042984508 P32913 0.0 0.0 0.04762282595038414 0.04174968972802162 38.761848026072705 25.0 1.0 no 13388 chrXV_573795r 33489 exception YOR132W 623 - CTTCATTCCGAATAATTAAG E|214|Q E|214|K VPS17 Vacuolar Protein Sorting 551.0 0 0 0 0 0.2583217119938284 P32913 0.04762282595038414 0.04174968972802162 36.49572597129321 30.0 1.0 no 13389 chrXV_574165 33492 exception YOR132W 990 + GACATGGCGACATTGTACGA D|331|E silent|GAC>GAT|D|331 VPS17 Vacuolar Protein Sorting 551.0 0 0 0 0 0.3497025260611912 P32913 1.0 47.35534678776247 50.0 1.0 no 13390 chrXV_574235r 33493 exception YOR132W 1063 - TCGCATGATAAAATGCCTGT M|360|I M|360|I R|361|P R|361|Q VPS17 Vacuolar Protein Sorting 551.0 0 0 0 0 -0.8889000727325144 P32913 0.14923883974552155 0.14923883974552155 0.0 0.0 44.32759961229175 40.0 1.0 no 13391 chrXV_602056r 33504 essential YOR143C 264 + TATCTTCCCAATTATATTAT L|90|V L|90|F P|91|A P|91|S THI80 THIamine metabolism 319.0 0 0 0 0 -0.3619307559459783 P35202 0.9512209892272948 0.9587849974632264 0.9562489986419678 0.9498909711837769 0.3014436066150665 0.04541637748479843 0.0 0.0 1.8414599895477293 2.7284200191497803 2.7565200328826904 3.4552800655364986 1.2951220273971558 2.1802260875701904 39.142110985980075 20.0 0.0 no 13392 chrXV_602134r 33505 essential YOR143C 186 + GACTTGAAGGTCTGTGCAGA D|63|E silent|GAC>GAT|D|63 THI80 THIamine metabolism 319.0 0 0 0 0 0.06547730462200152 P35202 0.9532920122146606 1.0 0.2994399964809418 49.44092629981789 50.0 0.0 no 13393 chrXV_602296 33506 essential YOR143C 27 - GTACCAATTTTAATACGTTC G|15|A G|15|D G|15|R G|15|S THI80 THIamine metabolism 319.0 0 0 0 0 -0.04990680624178778 P35202 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.7545202374458313 0.6376520395278931 0.5299150347709656 0.7282496094703674 0.9540200233459472 -0.365119993686676 0.5198199748992921 -0.3611400127410889 39.07472609722282 30.0 0.0 no 13394 chrXV_605644r 33508 essential YOR145C 505 + ACGATTCTATCGCACTATTG D|169|E silent|GAC>GAT|D|169 S|171|C S|171|F PNO1 Partner of NOb1 274.0 0 0 0 0 0.0044172217365871375 Q99216 0.9532920122146606 0.945252001285553 0.9294660091400146 0.7491300702095032 0.002231620252132416 0.0008635550038889049 43.79122732021187 40.0 0.0 no 13395 chrXV_605662 33509 essential YOR145C 490 - ATCGTCAAGATCAAACCCTA D|170|H D|170|N D|169|H D|169|N PNO1 Partner of NOb1 274.0 0 0 0 0 0.6747571929034377 Q99216 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.0 0.0 0.02204455249011517 0.20965462923049927 44.648538417039326 40.0 0.0 no 13396 chrXV_605723 33512 essential YOR145C 429 - CCAGGGTCTGTGGTAAATTT G|150|R G|150|S PNO1 Partner of NOb1 274.0 0 1 0 0 0.2679216203074575 Q99216 0.941340982913971 0.951104998588562 0.029261294752359387 0.8898559212684631 48.98928207518282 45.0 0.0 no 13397 chrXV_605795 33514 essential YOR145C 357 - AGCTTCAAGTGCTCGACCAA K|125|N silent|AAG>AAA|K|125 L|124|F silent|TTG>TTA|L|124 PNO1 Partner of NOb1 274.0 0 0 0 0 0.7710262213921975 Q99216 0.9355990290641784 0.9587849974632264 0.18745778501033786 0.012894227169454098 51.17660257352708 50.0 0.0 no 13398 chrXV_605811r 33515 essential YOR145C 338 + GACAAAAATTTATCCTCCTT T|114|R T|114|I PNO1 Partner of NOb1 274.0 0 0 0 0 1.8317971479549835 Q99216 0.9476869702339172 0.9472420215606691 0.3799284994602203 0.6460328698158264 40.02425737425421 30.0 0.0 no 13399 chrXV_605833r 33516 essential YOR145C 316 + TGACACCCTTGAGGAACAGT T|107|R T|107|I P|108|A P|108|S PNO1 Partner of NOb1 274.0 0 0 0 0 -1.6182946924039745 Q99216 0.9476869702339172 0.9472420215606691 0.9562489986419678 0.9498909711837769 0.003655235748738051 0.004191540647298098 0.062017366290092475 0.03065405413508415 49.93872580130096 50.0 0.0 no 13400 chrXV_605842r 33517 essential YOR145C 307 + CACACAGAATGACACCCTTG H|104|D H|104|Y H|104|Q silent|CAC>CAT|H|104 PNO1 Partner of NOb1 274.0 0 0 0 0 0.5850731111035246 Q99216 0.9473130106925964 0.9489949941635132 0.9588389992713928 0.015919825062155724 0.001944143557921052 0.003463702276349068 46.80349680827721 50.0 0.0 no 13401 chrXV_605907r 33519 essential YOR145C 242 + CACTTCAGCTAGCAAAACAC T|82|S T|82|I S|83|* S|83|L PNO1 Partner of NOb1 274.0 0 0 0 0 -0.17817440289427147 Q99216 0.9491789937019348 0.9472420215606691 0.9298099875450134 0.5171074271202087 0.08759595453739166 0.026637395843863487 43.06546872612791 45.0 0.0 no 13402 chrXV_605906r 33521 essential YOR145C 243 + ACTTCAGCTAGCAAAACACA T|82|S T|82|I S|83|* S|83|L PNO1 Partner of NOb1 274.0 0 0 0 0 -1.3110074612922031 Q99216 0.9491789937019348 0.9472420215606691 0.9298099875450134 0.5171074271202087 0.08759595453739166 0.026637395843863487 43.06546872612808 40.0 0.0 no 13403 chrXV_606010 33528 essential YOR145C 142 - TTCTTTTGCTGTGTTATTGT E|54|Q E|54|K PNO1 Partner of NOb1 274.0 0 1 0 0 0.07216134881811025 Q99216 0.956179976463318 0.9475290179252625 0.5783085823059082 0.912029266357422 46.2184766148996 30.0 0.0 no 13404 chrXV_608824r 33533 essential YOR148C 351 + GACTCCGAGCAAGATTCTAA D|118|E silent|GAC>GAT|D|118 S|119|C S|119|F SPP2 Suppressor of PrP 185.0 0 1 0 0 -1.5283584056336916 Q02521 0.9532920122146606 0.945252001285553 0.9294660091400146 0.840982973575592 0.12019726634025575 0.3335818350315094 45.67958982102232 45.0 0.0 no 13405 chrXV_608856r 33534 essential YOR148C 319 + ATGCTTTACTTCGGGGTATG A|108|G A|108|V SPP2 Suppressor of PrP 185.0 0 0 0 0 1.0812904252740698 Q02521 0.9484469890594482 0.9504740238189696 0.0 0.0 48.610419944874884 45.0 0.0 no 13406 chrXV_608875 33535 essential YOR148C 303 - GCATCTCCAAATTCCTCGAC A|108|P A|108|T D|107|H D|107|N SPP2 Suppressor of PrP 185.0 0 0 0 0 -0.09650131406513747 Q02521 0.9573720097541808 0.9523990154266356 0.9486550092697144 0.956179976463318 0.0 0.0 0.0329703614115715 0.08488323539495468 50.563917951383466 50.0 0.0 no 13407 chrXV_609050 33537 essential YOR148C 128 - TACTTTGAGGTTTATGCGAA S|49|T S|49|N SPP2 Suppressor of PrP 185.0 0 0 0 0 0.2621871693214098 Q02521 0.9512869715690612 0.9536849856376648 0.662056028842926 0.487346738576889 42.21988864332678 35.0 0.0 no 13408 chrXV_609087 33538 essential YOR148C 91 - ATCATCCCAATCGAATAAGT D|37|H D|37|N D|36|H D|36|N SPP2 Suppressor of PrP 185.0 0 0 0 0 0.70407332736583 Q02521 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.2239293456077576 0.6218414902687073 0.10958963632583618 0.6731671094894409 42.55100850273072 35.0 0.0 no 13409 chrXV_609172r 33540 essential YOR148C 3 + AGCAAGTTTTCACTTAAGTT S|2|R silent|AGC>AGT|S|2 SPP2 Suppressor of PrP 185.0 0 0 0 0 0.6530016303296614 Q02521 0.9417110085487366 0.5176475644111633 41.535169949712035 30.0 0.0 no 13410 chrXV_610225r 33542 essential YOR149C 1141 + AACAAATGGGCGTTCACATA Q|382|E Q|382|* SMP3 Stable Maintenance of pSRI 516.0 0 0 0 0 -0.11946534150707833 Q04174 0.9590039849281312 1.0 42.55131190061706 40.0 0.0 no 13411 chrXV_610239r 33545 essential YOR149C 1127 + CCACTTTCGTACCGAACAAA H|377|Q silent|CAC>CAT|H|377 H|377|D H|377|Y SMP3 Stable Maintenance of pSRI 516.0 0 0 0 0 0.4701561081395916 Q04174 0.9588389992713928 0.9473130106925964 0.9489949941635132 0.4315600693225861 0.2972728610038757 1.0 45.18364093257679 45.0 0.0 no 13412 chrXV_610272r 33546 essential YOR149C 1094 + AGCAGGAATTATCCAATTTT A|366|G A|366|V SMP3 Stable Maintenance of pSRI 516.0 0 0 0 0 0.5518427216123645 Q04174 0.9484469890594482 0.9504740238189696 0.5340441465377808 0.2253571301698685 41.566045654664954 30.0 0.0 no 13413 chrXV_610320r 33547 essential YOR149C 1046 + GCTTCTTTTTAACATAATCA L|350|V L|350|F L|351|V L|351|F SMP3 Stable Maintenance of pSRI 516.0 0 0 0 0 0.09390583777431097 Q04174 0.9512209892272948 0.9587849974632264 0.9512209892272948 0.9587849974632264 0.4000148177146912 0.03811506927013397 0.9489345550537108 0.13783958554267886 38.681449411231476 25.0 0.0 no 13414 chrXV_610478r 33549 essential YOR149C 888 + TCTACTTACGCAATCATATC S|297|C S|297|F T|298|S T|298|I SMP3 Stable Maintenance of pSRI 516.0 0 0 0 0 -0.007808163077382441 Q04174 0.945252001285553 0.9294660091400146 0.9491789937019348 0.9472420215606691 0.018859539180994037 0.012258836999535559 0.6581418514251709 0.467895656824112 41.311316766206566 35.0 0.0 no 13415 chrXV_610572r 33551 essential YOR149C 794 + TCCAAGATACACCCATCTGC P|266|R P|266|L P|266|A P|266|S SMP3 Stable Maintenance of pSRI 516.0 0 0 0 0 -1.4164541857139878 Q04174 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.008901945315301418 0.012332210317254066 0.21336814761161804 0.04794654622673988 51.922774321863976 50.0 0.0 no 13416 chrXV_610856r 33553 essential YOR149C 510 + TTCAAAAATTCGGTTATATT F|171|L silent|TTC>TTT|F|171 SMP3 Stable Maintenance of pSRI 516.0 0 0 0 0 1.2707466195084496 Q04174 0.9387490153312684 0.6248711347579956 33.40745859050253 20.0 0.0 no 13417 chrXV_610857r 33554 essential YOR149C 509 + TTTCAAAAATTCGGTTATAT F|171|L silent|TTC>TTT|F|171 SMP3 Stable Maintenance of pSRI 516.0 0 0 0 0 0.9580550363168652 Q04174 0.9387490153312684 0.6248711347579956 33.40745859050253 20.0 0.0 no 13418 chrXV_610917r 33555 essential YOR149C 449 + AATCTCAACTTTAACTGTAA I|151|M silent|ATC>ATT|I|151 S|152|* S|152|L SMP3 Stable Maintenance of pSRI 516.0 0 0 0 0 0.7890507828331177 Q04174 0.9598389863967896 0.9298099875450134 0.032582156360149384 1.0 35.0638616675829 25.0 0.0 no 13419 chrXV_611179 33558 essential YOR149C 190 - AGGCCCGTAAACCAATAATA silent|GGG>GGC|G|69 silent|GGG>GGA|G|69 G|69|A G|69|E SMP3 Stable Maintenance of pSRI 516.0 0 0 0 0 -1.117250195218172 Q04174 0.9499930143356324 0.9438679814338684 0.37602755427360535 0.1189572811126709 44.62035670994778 40.0 0.0 no 13420 chrXV_611238r 33559 essential YOR149C 128 + GGTCAAAGGTACCATCCCAT silent|GTC>GTG|V|44 silent|GTC>GTT|V|44 SMP3 Stable Maintenance of pSRI 516.0 0 0 0 0 0.06709883359380914 Q04174 53.13281412343105 50.0 0.0 no 13421 chrXV_611252r 33560 essential YOR149C 114 + ATGCAGTTCATGAAGGTCAA Q|40|E Q|40|* SMP3 Stable Maintenance of pSRI 516.0 0 0 0 0 -0.2319757825970661 Q04174 0.9590039849281312 0.3947170376777649 44.76257619504906 40.0 0.0 no 13422 chrXV_611277r 33562 essential YOR149C 89 + TTTCCAATGCATCGAGATTT F|31|L silent|TTC>TTT|F|31 Q|32|E Q|32|* SMP3 Stable Maintenance of pSRI 516.0 0 0 0 0 -0.857883065119068 Q04174 0.9387490153312684 0.9590039849281312 0.12490255385637285 0.0 44.52988936007631 35.0 0.0 no 13423 chrXV_611303 33563 essential YOR149C 66 - TCATCTGGATGAATATACGA E|29|Q E|29|K D|28|H D|28|N SMP3 Stable Maintenance of pSRI 516.0 0 0 0 0 -2.8962103908831565 Q04174 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.0 0.0 0.0 0.0 39.594380702953174 35.0 0.0 yes 13424 chrXV_611327r 33566 essential YOR149C 39 + ATCGGCCTAATGCTATGCCT I|14|M silent|ATC>ATT|I|14 silent|GGC>GGG|G|15 silent|GGC>GGT|G|15 SMP3 Stable Maintenance of pSRI 516.0 0 0 0 0 -0.8512319142061829 Q04174 0.9598389863967896 0.022270593792200092 54.71905606529333 50.0 0.0 no 13425 chrXV_613949 33571 essential YOR151C 2703 - TCTCCTGAAACTCTAACACC G|907|A G|907|E E|908|Q E|908|K RPB2 RNA Polymerase B 1224.0 0 0 0 0 0.7773161628993566 P08518 0.08196070790290833 0.0029444927349686627 0.13549350202083588 0.02934185042977333 -0.5830000042915344 -1.107200026512146 45.820802652180255 45.0 0.0 no 13426 chrXV_613992r 33574 essential YOR151C 2657 + ACATGGTACATACGATAAGT H|887|D H|887|Y RPB2 RNA Polymerase B 1224.0 0 1 0 0 -0.28813158851198045 P08518 0.2525867819786072 0.8903229236602783 1.32260000705719 0.032999999821186066 40.074925269893406 35.0 0.0 no 13427 chrXV_614091r 33576 essential YOR151C 2558 + TCTGTTTTTCAGATCTTATA L|854|V silent|CTG>TTG|L|854 RPB2 RNA Polymerase B 1224.0 0 0 0 0 1.2463891029584715 P08518 1.0 2.1279001235961914 40.754972217258064 25.0 0.0 no 13428 chrXV_614304r 33578 essential YOR151C 2345 + AACAAACTATAATGTGCGTA T|783|R T|783|I N|784|K silent|AAC>AAT|N|784 RPB2 RNA Polymerase B 1224.0 0 0 0 0 0.2509895693129014 P08518 0.004808017984032631 0.005894557572901249 0.0 3.9772000312805176 -1.176800012588501 1.9526000022888184 36.256456289276905 30.0 0.0 no 13429 chrXV_614352r 33582 essential YOR151C 2297 + TAACACTTACCAATCTGCGA N|767|K silent|AAC>AAT|N|767 T|768|S T|768|I RPB2 RNA Polymerase B 1224.0 0 0 0 0 0.1450270714146758 P08518 0.0 0.019505217671394348 0.02335959114134312 43.911678316790365 40.0 0.0 no 13430 chrXV_614423r 33585 essential YOR151C 2226 + ATTCATCCTTCTATGATTCT H|744|D H|744|Y P|745|A P|745|S RPB2 RNA Polymerase B 1224.0 0 0 0 0 0.004058671358753856 P08518 0.07773829996585846 0.002052749739959836 0.0 0.0 45.227872528443186 30.0 0.0 no 13431 chrXV_614659 33586 essential YOR151C 1993 - ACCTTCAATATCTTGATATT G|671|R G|671|S G|671|A G|671|D RPB2 RNA Polymerase B 1224.0 0 0 0 0 -0.11673929969996415 P08518 0.6663623452186584 0.8712955713272095 0.9695773124694824 0.6761396527290344 39.788313110511645 25.0 0.0 no 13432 chrXV_614660r 33587 essential YOR151C 1989 + ACCGAATATCAAGATATTGA silent|ACC>ACG|T|664 silent|ACC>ACT|T|664 T|664|S T|664|I RPB2 RNA Polymerase B 1224.0 0 0 0 0 0.7191750545596781 P08518 0.7119366526603699 0.18176707625389102 37.46573918254136 30.0 0.0 no 13433 chrXV_614709 33588 essential YOR151C 1943 - TTCTTACCTTTAATTCCTTA R|654|T R|654|K V|653|L V|653|I RPB2 RNA Polymerase B 1224.0 0 0 0 0 1.0719832134997334 P08518 0.3775801360607147 1.0 1.0 0.9962164163589478 43.15745044422306 25.0 0.0 no 13434 chrXV_614819 33589 essential YOR151C 1833 - TCTCTAATCATAGAAACTTC R|617|T R|617|K D|618|H D|618|N RPB2 RNA Polymerase B 1224.0 0 0 0 0 0.6110358075224909 P08518 0.09695930778980257 0.09720517694950104 0.07080542296171187 0.05817674472928047 1.7117999792099 0.7716000080108643 36.14391476518552 30.0 0.0 no 13435 chrXV_614853 33590 essential YOR151C 1799 - CCTTTCTTCTCAATGTTCTA K|606|N silent|AAG>AAA|K|606 R|605|T R|605|K RPB2 RNA Polymerase B 1224.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.8952592965746422 P08518 0.5168057680130005 0.003324661171063781 0.019153332337737083 47.231171584316996 35.0 0.0 no 13436 chrXV_614853r 33591 essential YOR151C 1796 + CCTTAGAACATTGAGAAGAA L|600|V L|600|F RPB2 RNA Polymerase B 1224.0 0 0 0 0 -1.691200223589304 P08518 0.1932942420244217 0.1722903549671173 37.54123904332539 35.0 0.0 no 13437 chrXV_614909r 33592 essential YOR151C 1740 + TTCGTCAATGGTGTTTGGCA F|581|L silent|TTC>TTT|F|581 silent|GTC>GTG|V|582 silent|GTC>GTT|V|582 RPB2 RNA Polymerase B 1224.0 0 0 0 0 -0.07404926375622356 P08518 0.06083793938159944 50.447442500959255 45.0 0.0 no 13438 chrXV_614935r 33596 essential YOR151C 1714 + ATCAATCACCTGACGCGACA Q|573|E Q|573|* S|574|* S|574|L RPB2 RNA Polymerase B 1224.0 0 0 0 0 0.7801108983923645 P08518 1.0 0.16883039474487305 48.708948035999526 50.0 0.0 no 13439 chrXV_615068 33599 essential YOR151C 1584 - AAACCACACGCTTGGCCTTC G|534|A G|534|D G|534|R G|534|S RPB2 RNA Polymerase B 1224.0 0 0 0 0 0.463780200334927 P08518 0.0 0.0 0.0 0.0 53.1421446873498 55.00000000000001 0.0 no 13440 chrXV_615060 33600 essential YOR151C 1592 - TCTTAACTAAACCACACGCT K|537|N silent|AAG>AAA|K|537 V|536|L V|536|I RPB2 RNA Polymerase B 1224.0 0 0 0 0 -0.1077710360212547 P08518 0.0 0.06880663335323334 0.08231709897518158 43.50810311163286 40.0 0.0 no 13441 chrXV_615080 33603 essential YOR151C 1572 - TGGCCTTCAGGAGTTTCTGC G|530|A G|530|D G|530|R G|530|S RPB2 RNA Polymerase B 1224.0 0 0 0 0 -0.8201223390248253 P08518 0.0 0.0 0.0 0.0 57.76045222058116 55.00000000000001 0.0 no 13442 chrXV_615115r 33604 essential YOR151C 1534 + GTCAATTGCATAATACACAT Q|513|E Q|513|* RPB2 RNA Polymerase B 1224.0 0 0 0 0 0.8966984439646011 P08518 0.01413807552307844 38.78609238430232 30.0 0.0 no 13443 chrXV_615228r 33606 essential YOR151C 1421 + TTCTAGGGCAGGTGTTTCTC S|475|C S|475|F RPB2 RNA Polymerase B 1224.0 0 0 0 0 0.2376104046365409 P08518 0.09729363769292833 0.05470387265086174 54.682060969961974 50.0 0.0 no 13444 chrXV_615295 33612 essential YOR151C 1357 - GTACTTAAGACCCGATGTTA K|458|N silent|AAG>AAA|K|458 RPB2 RNA Polymerase B 1224.0 0 0 0 0 -0.2328089689171469 P08518 0.028216594830155376 45.674053397915536 40.0 0.0 no 13445 chrXV_615305r 33613 essential YOR151C 1344 + AACGCAAAAACCATAACATC N|449|K silent|AAC>AAT|N|449 A|450|G A|450|V RPB2 RNA Polymerase B 1224.0 0 1 0 0 -0.4570616431730202 P08518 1.0 0.4473063051700592 0.3745659589767456 0.3799000084400177 0.6592000126838684 0.7778000235557556 36.19189585064385 35.0 0.0 no 13446 chrXV_615704 33616 essential YOR151C 948 - ACAAACCCGTCTTCAACACA V|323|L V|323|I silent|GGG>GGC|G|321 silent|GGG>GGA|G|321 RPB2 RNA Polymerase B 1224.0 0 0 0 0 0.6558241840133363 P08518 0.6909826397895813 0.4274108707904816 46.92512616245897 45.0 0.0 no 13447 chrXV_615788r 33617 essential YOR151C 861 + GCTTTAGGTATTATTCCAGA A|288|G A|288|V RPB2 RNA Polymerase B 1224.0 0 0 0 0 0.7998727833067432 P08518 0.0 0.0 46.58757414866511 35.0 0.0 no 13448 chrXV_615837r 33618 essential YOR151C 812 + CACATTACCATATATCAAAC T|272|R T|272|I RPB2 RNA Polymerase B 1224.0 0 1 0 0 0.7543202709168007 P08518 0.4751071333885193 0.4344658851623535 36.742700382937706 30.0 0.0 no 13449 chrXV_615892 33622 essential YOR151C 760 - ACCATAAAGCTTGACTTGAA G|260|R G|260|S G|260|A G|260|D RPB2 RNA Polymerase B 1224.0 0 1 0 0 0.4722353644159922 P08518 0.4334346652030945 0.8646299839019775 1.0 0.3007576465606689 40.71994022503958 35.0 0.0 no 13450 chrXV_616139 33626 essential YOR151C 513 - TTCTTTGATCTTAACATAAT K|177|N silent|AAG>AAA|K|177 RPB2 RNA Polymerase B 1224.0 0 0 0 0 1.2709287781003116 P08518 0.4839461147785187 34.74963551051826 20.0 0.0 no 13451 chrXV_616146 33627 essential YOR151C 506 - ATCTTAACATAATCGGTAAA R|175|T R|175|K RPB2 RNA Polymerase B 1224.0 0 0 0 0 -0.006813408813414856 P08518 0.007774796336889267 0.5701530575752258 34.317110178155424 25.0 0.0 no 13452 chrXV_616223 33631 essential YOR151C 429 - TCATATTTCAGTTCCCTACC E|150|Q E|150|K RPB2 RNA Polymerase B 1224.0 0 0 0 0 0.779260763067289 P08518 0.3433125615119934 0.3372830450534821 51.08317103742485 40.0 0.0 no 13453 chrXV_616237r 33632 essential YOR151C 412 + AAGCTATTGATGTTCCAGGT A|139|G A|139|V RPB2 RNA Polymerase B 1224.0 0 0 0 0 -0.9564754647983368 P08518 0.4067489504814148 0.41046392917633057 1.6410000324249268 1.4018000364303589 48.18053901490549 40.0 0.0 no 13454 chrXV_616310 33633 essential YOR151C 342 - TTACGTAAACGTGCTTCTTG R|120|P R|120|H RPB2 RNA Polymerase B 1224.0 0 0 0 0 -0.9741948339341616 P08518 0.0053105391561985025 0.003078216454014182 3.5785999298095703 6.0704002380371085 42.636733112008976 40.0 0.0 no 13455 chrXV_616323 33634 essential YOR151C 329 - CTTCTTGTGGATACAACGCA E|116|Q E|116|K RPB2 RNA Polymerase B 1224.0 0 0 0 0 -0.014929995704658722 P08518 0.12010874599218367 0.1681085079908371 -0.2251999974250793 -0.2736000120639801 46.74783653558803 45.0 0.0 no 13456 chrXV_616352r 33636 essential YOR151C 297 + CCAATGGTAAATGAATCTGA P|100|R P|100|L RPB2 RNA Polymerase B 1224.0 0 1 0 0 1.7481144823099537 P08518 0.0031205855775624514 0.007126450538635255 7.740699768066406 3.0703999996185303 38.45198051988075 35.0 0.0 no 13457 chrXV_616414 33637 essential YOR151C 238 - TCTACTGATGTTGTCTGATT R|86|T R|86|K S|85|T S|85|N RPB2 RNA Polymerase B 1224.0 0 0 0 0 -0.04503520403120671 P08518 0.638651967048645 1.0 0.5903564691543579 0.5102878212928772 44.49640774160713 35.0 0.0 no 13458 chrXV_631166 33641 essential YOR157C 566 - AATCATTCCAGATACCAGCC D|195|H D|195|N PUP1 PUtative Proteasome subunit 261.0 0 0 0 0 -3.0142470267653696 P25043 0.5529249906539917 0.6235060095787048 0.0 0.0 5.15723991394043 0.4913400113582611 50.112266316310645 45.0 0.0 yes 13459 chrXV_631276r 33649 essential YOR157C 453 + TACTACCTTTCTCTAGGATC Y|152|* silent|TAC>TAT|Y|152 Y|153|* silent|TAC>TAT|Y|153 PUP1 PUtative Proteasome subunit 261.0 0 0 0 0 -0.262750019225109 P25043 46.880624003349574 40.0 0.0 no 13460 chrXV_631390r 33652 essential YOR157C 339 + CAGCACCTATTTAAGTACCA H|115|D H|115|Y H|115|Q silent|CAC>CAT|H|115 PUP1 PUtative Proteasome subunit 261.0 0 0 0 0 -0.5399289722283127 P25043 0.6443489789962769 0.8417980074882507 0.6457110047340393 0.21285243332386014 1.0 0.4132746458053589 1.473080039024353 -1.776919960975647 -0.015979999676346782 47.14758348349653 40.0 0.0 no 13461 chrXV_631494 33654 essential YOR157C 238 - CTGCGTAACTGCCTCAGTAT silent|ACG>ACC|T|85 silent|ACG>ACA|T|85 PUP1 PUtative Proteasome subunit 261.0 0 0 0 0 -1.5617814071189116 P25043 52.22833718323284 50.0 0.0 no 13462 chrXV_631527 33657 essential YOR157C 205 - GGCACCAGCACACCATATTT A|75|P A|75|T G|74|A G|74|D PUP1 PUtative Proteasome subunit 261.0 0 0 0 0 -3.0081821542886344 P25043 0.5277130007743835 0.5914899706840515 0.5942080020904541 0.5266180038452148 0.005999078508466482 0.004758485592901707 0.0 0.0 2.2300400733947754 -0.19553999602794647 1.874559998512268 11.535400390625 6.142119884490968 0.6797599792480469 54.25873383141118 50.0 0.0 yes 13463 chrXV_631528 33658 essential YOR157C 204 - GCACCAGCACACCATATTTT G|74|A G|74|D A|75|P A|75|T PUP1 PUtative Proteasome subunit 261.0 0 0 0 0 -0.9734037834740537 P25043 0.5942080020904541 0.5266180038452148 0.5277130007743835 0.5914899706840515 0.0 0.0 0.005999078508466482 0.004758485592901707 1.874559998512268 11.535400390625 2.2300400733947754 -0.19553999602794647 6.142119884490968 0.6797599792480469 52.20136300532221 45.0 0.0 no 13464 chrXV_631663 33662 essential YOR157C 69 - GTACCCGTGGAAGTTGCCTT G|29|A G|29|D G|29|R G|29|S PUP1 PUtative Proteasome subunit 261.0 0 1 0 0 -2.1240977210495946 P25043 0.8289849758148193 0.8035820126533508 0.7936480045318604 0.859798014163971 0.02224933542311192 0.005431652069091797 0.0021784421987831593 0.05594424530863762 57.1922820359772 55.00000000000001 0.0 yes 13465 chrXV_631666r 33663 essential YOR157C 63 + CAACCTAAGGCAACTTCCAC P|23|A P|23|S P|23|R P|23|L PUP1 PUtative Proteasome subunit 261.0 0 0 0 0 0.13380875730485806 P25043 0.974582016468048 0.9655749797821044 0.8463199734687805 0.9568529725074768 0.051402807235717766 0.10563015937805176 0.07764334231615068 0.006416256539523602 47.80797354976096 50.0 0.0 no 13466 chrXV_631667r 33664 essential YOR157C 62 + ACAACCTAAGGCAACTTCCA Q|22|E Q|22|* P|23|A P|23|S PUP1 PUtative Proteasome subunit 261.0 0 0 0 0 -1.249975703780376 P25043 1.0172699689865112 0.974582016468048 0.9655749797821044 1.0 0.051402807235717766 0.10563015937805176 0.02962599694728852 47.807973549760895 45.0 0.0 no 13467 chrXV_631679r 33665 essential YOR157C 50 + AAACTCGCACACACAACCTA N|18|K silent|AAC>AAT|N|18 S|19|W S|19|L PUP1 PUtative Proteasome subunit 261.0 0 0 0 0 -0.07888871343597985 P25043 1.0089099407196045 0.8423150181770325 0.9935939908027648 1.0 0.00929652526974678 0.11467529833316804 44.90198709519541 45.0 0.0 no 13468 chrXV_631703r 33666 essential YOR157C 26 + TCAAAGAAATAATTTCTTAG Q|10|E Q|10|* PUP1 PUtative Proteasome subunit 261.0 0 0 0 0 0.9761182651413408 P25043 1.0181800127029421 1.0 28.81396048101743 20.0 0.0 no 13469 chrXV_633942 33667 essential YOR160W 103 + TCCAAAGATCAACTGTTGCC Q|36|E Q|36|* F|35|L silent|TTC>TTT|F|35 MTR10 Mrna TRansport defective 972.0 0 0 0 0 -0.4195254688494117 Q99189 0.9590039849281312 0.9387490153312684 0.0 0.0 46.7946556418737 45.0 1.0 no 13470 chrXV_633943r 33668 essential YOR160W 107 - ACCAGGCAACAGTTGATCTT W|42|S W|42|* W|42|C W|42|* MTR10 Mrna TRansport defective 972.0 0 0 0 0 -1.1371520724634492 Q99189 0.8858469724655151 0.8858469724655151 0.0 0.0 49.651934164050495 45.0 1.0 no 13471 chrXV_634179 33669 essential YOR160W 340 + TGGCGATCCAATTTTTAGAA A|115|G A|115|V MTR10 Mrna TRansport defective 972.0 0 0 0 0 -0.3041466018083819 Q99189 0.9484469890594482 0.9504740238189696 0.04245075583457947 0.0143984854221344 42.69469208338995 35.0 1.0 no 13472 chrXV_634277r 33670 essential YOR160W 441 - GCAATGTCTAAGGTTTCCTC A|154|P A|154|T MTR10 Mrna TRansport defective 972.0 0 0 0 0 -0.5471318099927351 Q99189 0.9573720097541808 0.9523990154266356 0.062455575913190835 0.10141368955373764 49.280660990715596 45.0 1.0 no 13473 chrXV_634300 33671 essential YOR160W 461 + ATCTACTTCCTTGACAGAAG S|155|C S|155|F T|156|S T|156|I MTR10 Mrna TRansport defective 972.0 0 0 0 0 -1.8808026354817924 Q99189 0.945252001285553 0.9294660091400146 0.9491789937019348 0.9472420215606691 0.01888127252459526 0.02555467747151852 0.07298101484775542 0.22484172880649567 43.66686293901165 40.0 1.0 no 13474 chrXV_634332r 33672 essential YOR160W 496 - ATCAATTAGTTCATGAATTC D|172|H D|172|N MTR10 Mrna TRansport defective 972.0 0 0 0 0 1.0269666146802712 Q99189 0.9486550092697144 0.956179976463318 0.08640427142381668 0.3433456420898437 35.546253487224995 25.0 1.0 no 13475 chrXV_634437 33674 essential YOR160W 598 + TTTCATTAGAACAAATTTTA S|201|* S|201|L MTR10 Mrna TRansport defective 972.0 0 0 0 0 0.4787219153491789 Q99189 0.9298099875450134 0.5636252760887146 31.01477583954022 15.0 1.0 no 13476 chrXV_634581r 33676 essential YOR160W 745 - AACGCAGAGACAATCAATAG V|255|L V|255|I C|254|S C|254|Y MTR10 Mrna TRansport defective 972.0 0 0 0 0 -0.03138329873491985 Q99189 0.9539830088615416 0.9574310183525084 0.9421560168266296 0.9290120005607604 0.02744208462536335 0.02765530347824097 0.2412536591291428 0.038415636867284775 37.966530582458184 40.0 1.0 no 13477 chrXV_634754 33677 essential YOR160W 915 + ACACGATTATTCGTAGAAGC R|307|G R|307|* T|306|R T|306|I MTR10 Mrna TRansport defective 972.0 0 0 0 0 -0.768525973110279 Q99189 0.8994590044021606 0.9476869702339172 0.9472420215606691 0.017900409176945686 0.008009863086044788 0.0470922589302063 41.60256229027476 40.0 1.0 no 13478 chrXV_634823r 33680 essential YOR160W 987 - ATCAATAATACCAAAACCAT L|335|F silent|TTG>TTA|L|335 MTR10 Mrna TRansport defective 972.0 0 1 0 0 0.3640338161344992 Q99189 0.9587849974632264 0.1153419390320778 35.464457192238 25.0 1.0 no 13479 chrXV_634851r 33681 essential YOR160W 1015 - ATCTAAGTCTTCATTTTTGC D|345|H D|345|N MTR10 Mrna TRansport defective 972.0 0 0 0 0 0.08694193099702617 Q99189 0.9486550092697144 0.956179976463318 0.006233818363398314 0.016758877784013748 42.41189220370581 30.0 1.0 no 13480 chrXV_634878 33682 essential YOR160W 1039 + TTTCCTATACTTTCCCCTTT S|348|C S|348|F silent|TCC>TCG|S|348 silent|TCC>TCT|S|348 MTR10 Mrna TRansport defective 972.0 0 0 0 0 0.0806543678150054 Q99189 0.945252001285553 0.9294660091400146 0.01170895341783762 0.01576588675379753 52.91689914087078 35.0 1.0 no 13481 chrXV_634994 33683 essential YOR160W 1155 + ACTCATTTACAATATCCATC H|387|D H|387|Y T|386|S T|386|I MTR10 Mrna TRansport defective 972.0 0 0 0 0 -0.5163721115830442 Q99189 0.9473130106925964 0.9489949941635132 0.9491789937019348 0.9472420215606691 0.0 0.0 0.5941049456596375 0.15818984806537628 40.541696888131696 30.0 1.0 no 13482 chrXV_635014 33684 essential YOR160W 1175 + AGGCCAGTTTTCATCTAAAG silent|GGC>GGG|G|393 silent|GGC>GGT|G|393 Q|394|E Q|394|* MTR10 Mrna TRansport defective 972.0 0 0 0 0 0.661154675052117 Q99189 0.9590039849281312 1.0 45.439976508760594 40.0 1.0 no 13483 chrXV_635017r 33685 essential YOR160W 1181 - CTTCCTCTTTAGATGAAAAC E|400|Q E|400|K E|399|D silent|GAG>GAA|E|399 MTR10 Mrna TRansport defective 972.0 0 0 0 0 0.2397482302788264 Q99189 0.956179976463318 0.9475290179252625 0.94931298494339 0.3214032053947449 0.15899348258972168 0.08760421723127365 39.25209701025693 35.0 1.0 no 13484 chrXV_635129r 33687 essential YOR160W 1293 - GCGGACTTAATTCTTATTAG A|438|P A|438|T K|436|N silent|AAG>AAA|K|436 MTR10 Mrna TRansport defective 972.0 0 0 0 0 0.7759641996291786 Q99189 0.9573720097541808 0.9523990154266356 0.9355990290641784 0.3779144883155823 0.7650363445281982 0.5134925246238708 40.74414038101588 35.0 1.0 no 13485 chrXV_635184 33688 essential YOR160W 1345 + AAGCCCCATTATTTTCCCTG A|450|G A|450|V silent|GCC>GCG|A|450 silent|GCC>GCT|A|450 MTR10 Mrna TRansport defective 972.0 0 0 0 0 0.8674211584954712 Q99189 0.9484469890594482 0.9504740238189696 0.0 0.0 54.54119316413926 45.0 1.0 no 13486 chrXV_635161 33689 essential YOR160W 1322 + CAACAATAGCTGGCAAATAA N|442|K silent|AAC>AAT|N|442 MTR10 Mrna TRansport defective 972.0 0 0 0 0 1.1455524974642133 Q99189 0.9439849853515624 0.5524920821189879 37.34334343036693 35.0 1.0 no 13487 chrXV_635199r 33690 essential YOR160W 1363 - TTCTTTAGCCATAGTCCTCA E|461|Q E|461|K MTR10 Mrna TRansport defective 972.0 0 0 0 0 0.017600218149224328 Q99189 0.956179976463318 0.9475290179252625 0.25363218784332275 0.07905121892690659 52.6539241391041 40.0 1.0 no 13488 chrXV_635200r 33691 essential YOR160W 1364 - TTTCTTTAGCCATAGTCCTC E|461|Q E|461|K MTR10 Mrna TRansport defective 972.0 0 0 0 0 -0.298583017477815 Q99189 0.956179976463318 0.9475290179252625 0.25363218784332275 0.07905121892690659 51.62211053580813 40.0 1.0 no 13489 chrXV_635316 33692 essential YOR160W 1477 + TTCTTGGTAGATATACCGAA L|494|V L|494|F MTR10 Mrna TRansport defective 972.0 0 0 0 0 -1.0857929186097457 Q99189 0.9512209892272948 0.9587849974632264 0.0 0.0 42.344989023005716 35.0 1.0 no 13490 chrXV_635343r 33693 essential YOR160W 1507 - TTCTAGTAGTTCTGGATGCT E|509|Q E|509|K MTR10 Mrna TRansport defective 972.0 0 0 0 0 0.8457792654736559 Q99189 0.956179976463318 0.9475290179252625 0.2738805711269379 0.029294699430465695 48.97056822510791 40.0 1.0 no 13491 chrXV_635387 33695 essential YOR160W 1548 + AACGGTTTTCAACTGCATGA N|517|K silent|AAC>AAT|N|517 MTR10 Mrna TRansport defective 972.0 0 0 0 0 0.3167697299448309 Q99189 0.9439849853515624 0.9921171069145204 44.29865216564088 40.0 1.0 no 13492 chrXV_635471 33697 essential YOR160W 1632 + GACTGCTCTAAACTATTAGT D|545|E silent|GAC>GAT|D|545 C|546|W silent|TGC>TGT|C|546 MTR10 Mrna TRansport defective 972.0 0 0 0 0 -0.3274353581753447 Q99189 0.9532920122146606 0.9286419749259948 0.0 0.0 41.304884757715506 35.0 1.0 no 13493 chrXV_635658 33698 essential YOR160W 1819 + TCGAGGCTTTGATTCCTCAA I|607|M silent|ATC>ATT|I|607 A|609|G A|609|V MTR10 Mrna TRansport defective 972.0 0 0 0 0 -0.22462632224779924 Q99189 0.9598389863967896 0.9484469890594482 0.9504740238189696 0.035653334110975266 0.3738950192928314 0.26492348313331604 49.92997734664465 45.0 1.0 no 13494 chrXV_635690r 33699 essential YOR160W 1854 - ATCTGTGGAGCCAAGAGCGT Q|624|H silent|CAG>CAA|Q|624 MTR10 Mrna TRansport defective 972.0 0 0 0 0 0.9101825617182572 Q99189 0.9570760130882264 0.09861522912979126 54.30339134776392 55.00000000000001 1.0 no 13495 chrXV_635705r 33700 essential YOR160W 1869 - TCAATCTTATCAGCAATCTG D|630|H D|630|N K|628|N silent|AAG>AAA|K|628 MTR10 Mrna TRansport defective 972.0 0 0 0 0 -0.4113271059580169 Q99189 0.9486550092697144 0.956179976463318 0.9355990290641784 0.0102647477760911 0.019960060715675357 0.2986553609371185 41.035579079539794 35.0 1.0 no 13496 chrXV_635784 33702 essential YOR160W 1945 + GATCGGAACCTTTACTCCCC S|650|W S|650|L MTR10 Mrna TRansport defective 972.0 0 0 0 0 -0.09573035853720356 Q99189 0.9288619756698608 0.9298099875450134 0.018015170469880104 0.3236680924892425 54.778750426270676 55.00000000000001 1.0 no 13497 chrXV_635800r 33703 essential YOR160W 1964 - TCCAAATAAATTCTATCCTG W|661|S W|661|* W|661|C W|661|* MTR10 Mrna TRansport defective 972.0 0 0 0 0 -0.26763736831150403 Q99189 0.8858469724655151 0.8858469724655151 0.036139853298664086 0.019494323059916496 38.39696991130728 30.0 1.0 no 13498 chrXV_635802r 33704 essential YOR160W 1966 - CTTCCAAATAAATTCTATCC W|661|C W|661|* W|661|S W|661|* MTR10 Mrna TRansport defective 972.0 0 0 0 0 -0.4118419814991627 Q99189 0.8858469724655151 0.8858469724655151 0.019494323059916496 0.036139853298664086 38.59488372026556 30.0 1.0 no 13499 chrXV_649324 33706 essential YOR168W 21 + ACTCAGCTGTTTTCACAGGT Q|9|E Q|9|* T|8|S T|8|I GLN4 GLutamiNe metabolism 809.0 0 0 0 0 -0.5703009734674716 P13188 0.9590039849281312 0.9491789937019348 0.9472420215606691 1.0 0.1245872527360916 0.5034412741661072 52.417966813071814 45.0 1.0 no 13500 chrXV_649325 33707 essential YOR168W 22 + CTCAGCTGTTTTCACAGGTT Q|9|E Q|9|* L|10|V silent|CTG>TTG|L|10 GLN4 GLutamiNe metabolism 809.0 0 0 0 0 -0.4162943202343584 P13188 0.9590039849281312 0.9512209892272948 1.0 0.3494105935096741 2.0084400177001958 52.20554967777786 45.0 1.0 no 13501 chrXV_649597 33709 essential YOR168W 294 + GGCGAGGCATCCACCAAAAT silent|GGC>GGG|G|99 silent|GGC>GGT|G|99 GLN4 GLutamiNe metabolism 809.0 0 0 0 0 -0.0070097337057729294 P13188 51.44553684208711 55.00000000000001 1.0 no 13502 chrXV_649607r 33710 essential YOR168W 307 - TTCATTCATACCCATTTTGG E|109|Q E|109|K M|107|I M|107|I GLN4 GLutamiNe metabolism 809.0 0 0 0 0 -0.6278780855449212 P13188 0.956179976463318 0.9475290179252625 0.9553959965705872 0.9553959965705872 0.5406047105789185 1.0 0.03590571880340576 0.03590571880340576 2.0311601161956787 2.0311601161956787 46.38642181643712 35.0 1.0 no 13503 chrXV_649761 33712 essential YOR168W 458 + AAACTTAAAGGAGCTGAAGT N|154|K silent|AAC>AAT|N|154 GLN4 GLutamiNe metabolism 809.0 0 1 0 0 -0.7072373406167611 P13188 0.9439849853515624 0.9326820373535156 37.045359034318146 35.0 1.0 no 13504 chrXV_649815 33714 essential YOR168W 512 + CCAAGAAGTCTTAAAACTTT Q|172|E Q|172|* GLN4 GLutamiNe metabolism 809.0 0 1 0 0 -0.324184900594614 P13188 0.9590039849281312 0.5896567702293396 36.557696778826475 30.0 1.0 no 13505 chrXV_649815r 33715 essential YOR168W 515 - CCAAAAGTTTTAAGACTTCT L|178|F silent|TTG>TTA|L|178 GLN4 GLutamiNe metabolism 809.0 0 0 0 0 0.6399440909156251 P13188 0.9587849974632264 0.5564452409744263 2.9099199771881104 38.037402426857795 30.0 1.0 no 13506 chrXV_649942r 33718 essential YOR168W 642 - TCATTGAACATAGTCCTCTT E|221|Q E|221|K GLN4 GLutamiNe metabolism 809.0 0 0 0 0 0.4945729561670271 P13188 0.956179976463318 0.9475290179252625 0.3004815578460693 0.2930105030536652 -0.816860020160675 -0.7742199897766113 44.97324947264917 35.0 1.0 no 13507 chrXV_649937r 33719 essential YOR168W 637 - GAACATAGTCCTCTTTGGAC M|218|I M|218|I GLN4 GLutamiNe metabolism 809.0 0 0 0 0 -0.2185400788796651 P13188 0.9553959965705872 0.9553959965705872 0.3845161497592926 0.3845161497592926 1.1291999816894531 1.1291999816894531 46.79016435892254 45.0 1.0 no 13508 chrXV_649971r 33720 essential YOR168W 671 - CCACTTTATGCAAATCACCT V|230|L V|230|M silent|GTG>GTC|V|230 silent|GTG>GTA|V|230 GLN4 GLutamiNe metabolism 809.0 0 0 0 0 0.5216433630403413 P13188 0.9539830088615416 0.9587630033493042 0.33003881573677063 0.09740588814020157 1.9943399429321291 0.2983199954032898 46.773796306508245 40.0 1.0 no 13509 chrXV_650029 33721 essential YOR168W 726 + GAACACCTTGAGGTTACTGG H|244|D H|244|Y H|244|Q silent|CAC>CAT|H|244 GLN4 GLutamiNe metabolism 809.0 0 0 0 0 0.021678752472136083 P13188 0.9473130106925964 0.9489949941635132 0.9588389992713928 0.0 0.0 0.0 1.1281399726867676 2.5159199237823486 1.5968999862670898 47.57236958936369 50.0 1.0 no 13510 chrXV_650081r 33725 essential YOR168W 781 - ACCAATATGCAAATATCCAT G|267|R G|267|S G|267|A G|267|D GLN4 GLutamiNe metabolism 809.0 0 0 0 0 -4.228881391242028 P13188 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 0.5277000069618225 0.4527600109577179 -0.1250399947166443 0.8654800057411194 40.656417528199775 30.0 1.0 yes 13511 chrXV_650131 33726 essential YOR168W 828 + GGCTATGCTAAATATCACAA silent|GGC>GGG|G|277 silent|GGC>GGT|G|277 GLN4 GLutamiNe metabolism 809.0 0 0 0 0 0.7099065453781369 P13188 40.576420694305284 35.0 1.0 no 13512 chrXV_650172 33728 essential YOR168W 869 + TGACGATACCAACCCCGAAA D|291|E silent|GAC>GAT|D|291 GLN4 GLutamiNe metabolism 809.0 0 0 0 0 -1.804774826770944 P13188 0.9532920122146606 0.0 1.3784400224685671 47.530120490413644 50.0 1.0 no 13513 chrXV_650184r 33729 essential YOR168W 884 - ATTCAGGAGCTTCCTTTTCG E|301|Q E|301|K GLN4 GLutamiNe metabolism 809.0 0 1 0 0 0.008187597443208405 P13188 0.956179976463318 0.9475290179252625 0.5755124092102051 1.0 0.7501000165939331 0.6044999957084656 51.099820901971206 45.0 1.0 no 13514 chrXV_650216r 33731 essential YOR168W 916 - CCAAGAAACCATTCTCTTAA W|312|S W|312|* GLN4 GLutamiNe metabolism 809.0 0 1 0 0 -0.16540015982757958 P13188 0.8858469724655151 0.0 5.02046012878418 41.06631084421639 35.0 1.0 no 13515 chrXV_650448r 33734 essential YOR168W 1148 - TCATATCTCTGAATTCTTGC M|389|I M|389|I D|388|H D|388|N GLN4 GLutamiNe metabolism 809.0 0 0 0 0 0.28237281140627696 P13188 0.9553959965705872 0.9553959965705872 0.9486550092697144 0.956179976463318 0.0 0.0 0.1622055023908615 0.5162160396575928 1.6913000345230105 1.6913000345230105 -0.20494000613689425 0.1031000018119812 43.13953459689321 35.0 1.0 no 13516 chrXV_650488r 33735 essential YOR168W 1188 - ATTCTTAAGATAGCTTCACC R|402|T R|402|K GLN4 GLutamiNe metabolism 809.0 0 1 0 0 -1.6852146979408684 P13188 0.932735025882721 0.955805003643036 0.0 0.0 -1.6981600522994995 -0.4342400133609772 43.53396712834348 35.0 1.0 no 13517 chrXV_650526 33738 essential YOR168W 1223 + TTCACCAAGCCCACAAATGT S|409|* S|409|L P|410|A P|410|S GLN4 GLutamiNe metabolism 809.0 0 1 0 0 0.4058543397087057 P13188 0.9298099875450134 0.9562489986419678 0.9498909711837769 0.017295289784669876 0.1706816405057907 0.4224717319011688 -1.1683199405670166 0.4523000121116638 0.5149999856948853 49.35268315618345 45.0 1.0 no 13518 chrXV_650536r 33739 essential YOR168W 1236 - GCAATCAAGTCCCACATTTG A|419|P A|419|T L|417|F silent|TTG>TTA|L|417 GLN4 GLutamiNe metabolism 809.0 0 0 0 0 -0.2553764392710435 P13188 0.9573720097541808 0.9523990154266356 0.9587849974632264 0.0 0.0 0.03959272429347038 5.758299827575684 2.704659938812256 2.520020008087158 48.15364726524222 45.0 1.0 no 13519 chrXV_650619 33740 essential YOR168W 1316 + TTACGATTTTACACATTGTT Y|440|* silent|TAC>TAT|Y|440 GLN4 GLutamiNe metabolism 809.0 0 0 0 0 0.31408054093053256 P13188 38.69387300332989 25.0 1.0 no 13520 chrXV_650743r 33745 essential YOR168W 1443 - CGACCATATTCTCTTTGAGC G|487|A G|487|D G|487|R G|487|S GLN4 GLutamiNe metabolism 809.0 0 0 0 0 0.16664451176212694 P13188 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.11448323726654053 0.00412724120542407 0.0029783095233142376 0.019972853362560272 4.2175798416137695 19.020240783691406 17.197759628295902 10.476659774780273 48.00920950900917 45.0 1.0 no 13521 chrXV_650777r 33746 essential YOR168W 1477 - TCTTTTGGATAAAACTGTAC R|499|T R|499|K GLN4 GLutamiNe metabolism 809.0 0 0 0 0 -2.0282053352690976 P13188 0.932735025882721 0.955805003643036 0.0 0.0 0.22509999573230746 0.058540001511573785 36.1651903813883 30.0 1.0 yes 13522 chrXV_650875 33747 essential YOR168W 1572 + CGCAGACGTGGTGTTCCTCC silent|CGC>CGG|R|525 silent|CGC>CGT|R|525 R|527|G R|527|C GLN4 GLutamiNe metabolism 809.0 0 0 0 0 0.2974718066124172 P13188 0.8994590044021606 0.8926740288734436 0.0 0.0 3.5807399749755864 1.8728200197219849 59.920599415432655 65.0 1.0 no 13523 chrXV_650942 33749 essential YOR168W 1639 + CCACAAACATTCAAGTTGTG T|548|R T|548|I silent|ACC>ACG|T|547 silent|ACC>ACT|T|547 GLN4 GLutamiNe metabolism 809.0 0 0 0 0 -2.4776176914352885 P13188 0.9476869702339172 0.9472420215606691 0.012564744800329208 0.06872466951608658 -0.5429999828338623 -0.8744800090789795 41.42050329819824 40.0 1.0 yes 13524 chrXV_650942r 33750 essential YOR168W 1642 - CCTCACAACTTGAATGTTTG silent|GTG>GTC|V|553 silent|GTG>GTA|V|553 R|554|T R|554|K GLN4 GLutamiNe metabolism 809.0 0 0 0 0 -0.10006064716117634 P13188 0.932735025882721 0.955805003643036 0.0347064733505249 0.4343658685684204 1.0730199813842771 -0.488759994506836 42.73612493957955 40.0 1.0 no 13525 chrXV_650988r 33751 essential YOR168W 1688 - ATCTCGGTGTGGTATCTTCT R|569|T R|569|K silent|CCG>CCC|P|568 silent|CCG>CCA|P|568 GLN4 GLutamiNe metabolism 809.0 0 0 0 0 -1.7920313416358655 P13188 0.932735025882721 0.955805003643036 0.0 0.0 0.10096000134944916 -0.6444000005722046 52.66015102052921 45.0 1.0 no 13526 chrXV_651004r 33753 essential YOR168W 1704 - TCCAACACAAACATTAATCT L|574|F silent|TTG>TTA|L|574 D|575|H D|575|N GLN4 GLutamiNe metabolism 809.0 0 0 0 0 -1.0185411449808757 P13188 0.9587849974632264 0.9486550092697144 0.956179976463318 0.08954412490129471 0.061653658747673035 0.1779664009809494 3.5261800289154053 -0.2593399882316589 -0.7431600093841553 37.75228304017611 30.0 1.0 no 13527 chrXV_651076 33755 essential YOR168W 1773 + GCAACTATTCCTTACAGACC A|592|G A|592|V T|593|S T|593|I GLN4 GLutamiNe metabolism 809.0 0 0 0 0 0.25019994841407545 P13188 0.9484469890594482 0.9504740238189696 0.9491789937019348 0.9472420215606691 0.006622211541980505 1.0 0.2202071249485016 0.02348940446972847 1.3994200229644775 0.02692000009119511 0.4322800040245056 -0.08079999685287476 48.25495102909832 45.0 1.0 no 13528 chrXV_651103r 33758 essential YOR168W 1803 - ACAGTTCTTTCACCAAATTC V|608|L V|608|I R|606|T R|606|K GLN4 GLutamiNe metabolism 809.0 0 0 0 0 0.7101519564799881 P13188 0.9539830088615416 0.9574310183525084 0.932735025882721 0.955805003643036 0.29390740394592285 0.39950653910636896 1.0 0.6187040209770203 0.5173799991607666 0.724560022354126 2.429539918899536 1.1389800310134888 43.2346164360639 35.0 1.0 no 13529 chrXV_658868 33761 essential YOR174W 121 + AACTCTACGAAGATTTGTGC L|42|V L|42|F silent|CTC>CTG|L|42 silent|CTC>CTT|L|42 MED4 MEDiator complex 284.0 0 0 0 0 0.4529879599036896 Q12343 0.4784932434558869 0.018685758113861084 41.61948170931629 40.0 1.0 no 13530 chrXV_658939r 33762 essential YOR174W 195 - TCCTTGGCAATATCAAGGTT K|71|N silent|AAG>AAA|K|71 D|72|H D|72|N MED4 MEDiator complex 284.0 0 0 0 0 -0.43558540147818137 Q12343 0.3771884441375733 0.06814521551132202 0.24935422837734225 47.420286753186026 40.0 1.0 no 13531 chrXV_658955r 33763 essential YOR174W 211 - ATCAGTTCTGATCAAATCCT D|77|H D|77|N MED4 MEDiator complex 284.0 0 0 0 0 0.6645549395214307 Q12343 0.005911359563469887 0.016621563583612442 44.253169747626714 35.0 1.0 no 13532 chrXV_659028r 33764 essential YOR174W 284 - TGTCAATCTTCTGTAAGTTG D|101|H D|101|N MED4 MEDiator complex 284.0 0 0 0 0 0.5155042823789927 Q12343 0.022654933854937557 0.2339167147874832 41.46310593272296 35.0 1.0 no 13533 chrXV_659131r 33766 essential YOR174W 387 - AACTCTACTTGTTCAAGCAT E|135|D silent|GAG>GAA|E|135 E|135|Q E|135|K MED4 MEDiator complex 284.0 0 0 0 0 -0.7651203348651632 Q12343 0.15525740385055542 0.2534770667552948 0.23537859320640564 43.29254791715869 35.0 1.0 no 13534 chrXV_659187 33767 essential YOR174W 440 + AATCAATTCGACAGAGTTGT I|148|M silent|ATC>ATT|I|148 MED4 MEDiator complex 284.0 0 0 0 0 -0.5639509833611553 Q12343 0.01008494570851326 40.58790571252473 35.0 1.0 no 13535 chrXV_659242 33768 essential YOR174W 495 + ATACCACCAACGTTCGACAA P|167|A P|167|S P|167|R P|167|L MED4 MEDiator complex 284.0 0 0 0 0 0.276566598504633 Q12343 0.0 0.0 0.0 0.0 46.241687440987214 45.0 1.0 no 13536 chrXV_659276r 33773 essential YOR174W 532 - TGCGGGCCATATAAAATTGT A|184|P A|184|T W|182|C W|182|* MED4 MEDiator complex 284.0 0 0 0 0 0.1828145519548968 Q12343 0.0 0.0 0.0 44.77876559200586 40.0 1.0 no 13537 chrXV_659293r 33774 essential YOR174W 549 - CTTCGTAGGGCATCCTCTGC R|189|P R|189|Q MED4 MEDiator complex 284.0 0 0 0 0 -0.8222027911592271 Q12343 0.0 0.0 59.01680344366542 60.0 1.0 no 13538 chrXV_659307r 33776 essential YOR174W 563 - TAGCAAGCATTCCTCTTCGT A|194|P A|194|T MED4 MEDiator complex 284.0 0 0 0 0 -0.4277508105687196 Q12343 0.0 0.0 52.07308012061492 45.0 1.0 no 13539 chrXV_659333r 33778 essential YOR174W 589 - TAGCTCTTTACTATGTAATG E|202|D silent|GAG>GAA|E|202 E|202|Q E|202|K MED4 MEDiator complex 284.0 0 0 0 0 0.7163307230828913 Q12343 0.0 0.0 0.0 38.89940420384153 30.0 1.0 no 13540 chrXV_662497 33781 essential YOR176W 96 + GCACAAAAGAGATCACCCAC Q|34|E Q|34|* A|33|G A|33|V HEM15 HEMe biosynthesis 393.0 0 0 0 0 0.09232863692271066 P16622 1.0329899787902832 1.0146000385284424 1.0151900053024292 0.9188849925994872 0.3593289256095886 0.24007929861545566 45.99238495801012 50.0 1.0 no 13541 chrXV_662513r 33782 essential YOR176W 115 - GTTCATCAAAACAATTCCTG M|44|I M|44|I L|43|F silent|TTG>TTA|L|43 HEM15 HEMe biosynthesis 393.0 0 0 0 0 0.5432959830234684 P16622 0.8068119883537292 0.8068119883537292 0.9146090149879456 0.03135719895362854 0.03135719895362854 0.5746895670890808 0.5986599922180176 0.5986599922180176 -0.551859974861145 39.47477498511688 35.0 1.0 no 13542 chrXV_662601r 33783 essential YOR176W 203 - ACTTAGCACTAATGGGAATT K|74|N silent|AAG>AAA|K|74 A|73|P A|73|T HEM15 HEMe biosynthesis 393.0 0 0 0 0 -0.7195495077663274 P16622 0.9181050062179564 0.9602019786834716 0.9122859835624696 0.17890894412994385 0.23430563509464264 0.3412800133228302 -1.7886999845504759 0.4940400123596192 0.03951999917626381 5.010680198669434 0.6238399744033813 41.236783251311 35.0 1.0 no 13543 chrXV_662608r 33784 essential YOR176W 210 - TTCTGATACTTAGCACTAAT Q|76|H silent|CAG>CAA|Q|76 HEM15 HEMe biosynthesis 393.0 0 0 0 0 -0.6272844049183506 P16622 0.6876109838485718 0.0 3.885720014572144 40.04707695770031 30.0 1.0 no 13544 chrXV_662609r 33785 essential YOR176W 211 - CTTCTGATACTTAGCACTAA Q|76|H silent|CAG>CAA|Q|76 HEM15 HEMe biosynthesis 393.0 0 0 0 0 -0.5658863440130517 P16622 0.6876109838485718 0.0 3.885720014572144 41.899098952094505 35.0 1.0 no 13545 chrXV_662666r 33786 essential YOR176W 268 - CCTATATTGCTTCTCTATCT R|96|T R|96|K HEM15 HEMe biosynthesis 393.0 0 0 0 0 -0.3364114156726281 P16622 0.9165300130844116 0.9667710065841676 0.5126468539237976 0.8479969501495361 1.2377599477767944 -0.2885600030422211 47.79846057458354 35.0 1.0 no 13546 chrXV_662677 33787 essential YOR176W 276 + AAGCAATATAGGGAAATTGG Q|94|E Q|94|* HEM15 HEMe biosynthesis 393.0 0 0 0 0 -0.7286416321887479 P16622 0.83890700340271 0.04236866906285286 0.5536400079727173 36.42745022666418 35.0 1.0 no 13547 chrXV_662705r 33789 essential YOR176W 307 - CTCAGACCATTTCCGGATTG E|109|Q E|109|K W|107|C W|107|* HEM15 HEMe biosynthesis 393.0 0 0 0 0 -0.19144123919411507 P16622 0.9159709811210632 0.8796200156211853 0.6073219776153564 0.2984071671962738 0.3612942695617676 0.0008079856052063407 -0.5139399766921997 -0.4819999933242798 2.160599946975708 1.1128400564193726 50.41546984535142 50.0 1.0 no 13548 chrXV_662707r 33790 essential YOR176W 309 - TACTCAGACCATTTCCGGAT E|109|D silent|GAG>GAA|E|109 E|109|Q E|109|K HEM15 HEMe biosynthesis 393.0 0 0 0 0 0.2934537208464491 P16622 0.932224988937378 0.9159709811210632 0.8796200156211853 0.1496667116880417 0.2984071671962738 0.3612942695617676 0.5668200254440308 -0.5139399766921997 -0.4819999933242798 50.10250343339072 45.0 1.0 no 13549 chrXV_662721 33791 essential YOR176W 320 + GTCTGAGTATCAAGCCACTG S|108|C S|108|F HEM15 HEMe biosynthesis 393.0 0 0 0 0 0.3335521940814873 P16622 0.6124290227890015 0.5975639820098877 0.0021930616348981857 0.0011039155069738626 -0.4986400008201599 3.279119968414306 49.93967487722245 50.0 1.0 no 13550 chrXV_663000 33798 essential YOR176W 599 + TACAAATGAAGGTCTAATCA T|201|R T|201|I HEM15 HEMe biosynthesis 393.0 0 0 0 0 0.2029630038846084 P16622 0.8446419835090637 0.8606089949607849 0.09169841557741164 0.06279579550027847 -0.5964999794960022 -0.2110999971628189 2.0687899589538574 0.4472699761390686 35.51933809206872 30.0 1.0 no 13551 chrXV_663241r 33810 essential YOR176W 843 - GCTGTCTGCGCTCCCAACCA A|288|P A|288|T Q|286|H silent|CAG>CAA|Q|286 HEM15 HEMe biosynthesis 393.0 0 0 0 0 0.2373240881241444 P16622 0.9423760175704956 0.9113420248031616 0.8536329865455627 0.2424997389316559 0.5064424872398376 0.1981550753116608 -0.7338600158691406 0.5312600135803223 0.032419998198747635 -1.3380800485610962 0.7459200024604797 0.17015999555587769 63.56447402875284 65.0 1.0 no 13552 chrXV_675947r 33813 essential YOR181W 11 - TTTCCTTATCTGAAGAGTTT E|10|Q E|10|K K|9|N silent|AAG>AAA|K|9 LAS17 633.0 0 1 0 0 -0.2411794676044572 Q12446 0.956179976463318 0.9475290179252625 0.9355990290641784 0.038388267159461975 0.03044298849999905 0.0 42.87590543586265 30.0 1.0 no 13553 chrXV_676148r 33819 essential YOR181W 212 - GGTCCCAGATAACTCCTCTA D|77|H D|77|N W|76|C W|76|* LAS17 633.0 0 0 0 0 -0.68996249961446 Q12446 0.9486550092697144 0.956179976463318 0.8858469724655151 0.0 0.0 0.0 54.608150308868005 50.0 1.0 no 13554 chrXV_676404r 33821 essential YOR181W 468 - TCAATCAATGACTCCCCTCT D|163|H D|163|N L|161|F silent|TTG>TTA|L|161 LAS17 633.0 0 0 0 0 0.972858869556558 Q12446 0.9486550092697144 0.956179976463318 0.9587849974632264 0.10078274458646774 0.4775162637233734 0.03210141137242317 51.110179239121074 45.0 1.0 no 13555 chrXV_676414 33822 essential YOR181W 475 + AGTCATTGATTGACAATCAA S|160|* S|160|L LAS17 633.0 0 0 0 0 0.7986572256985188 Q12446 0.9298099875450134 0.02323899231851101 38.092540634598954 30.0 1.0 no 13556 chrXV_676490 33823 essential YOR181W 551 + TCCTCCCCCTCCTCCGCCAA P|185|R P|185|L P|185|A P|185|S LAS17 633.0 0 0 0 0 -1.0590308063281986 Q12446 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.027604173868894574 0.02375820092856884 0.2988865673542023 0.07349713146686554 70.88790514552653 70.0 1.0 no 13557 chrXV_676503r 33826 essential YOR181W 567 - TCAAATGTTTCGGCCGTTGG D|196|H D|196|N LAS17 633.0 0 0 0 0 0.01951147904693662 Q12446 0.9486550092697144 0.956179976463318 0.11742132157087325 0.5115311145782471 49.66455172286066 50.0 1.0 no 13558 chrXV_676532r 33827 essential YOR181W 596 - TATCGGAAAATGAACTTGTT D|205|H D|205|N LAS17 633.0 0 0 0 0 -0.377441781396819 Q12446 0.9486550092697144 0.956179976463318 0.0920984297990799 0.4293436110019684 35.802119671364665 30.0 1.0 no 13559 chrXV_676549r 33828 essential YOR181W 613 - TGCTGTTGTCGAATTGATAT A|211|P A|211|T LAS17 633.0 0 0 0 0 0.8529767968144539 Q12446 0.9573720097541808 0.9523990154266356 0.37515440583229065 0.7180955410003662 42.801036179679386 35.0 1.0 no 13560 chrXV_676605r 33830 essential YOR181W 669 - TTTCTTACTTCAGGAGATGC R|229|T R|229|K LAS17 633.0 0 0 0 0 0.07359305408739236 Q12446 0.932735025882721 0.955805003643036 0.5527384877204895 0.886061429977417 45.75199842366021 40.0 1.0 no 13561 chrXV_676793 33836 essential YOR181W 854 + AACAAACCCATTTCCATTTC T|286|R T|286|I N|287|K silent|AAC>AAT|N|287 LAS17 633.0 0 0 0 0 0.7692391490077413 Q12446 0.9476869702339172 0.9472420215606691 0.9439849853515624 0.5623307228088379 0.24891448020935056 0.917231261730194 44.073854298654624 35.0 1.0 no 13562 chrXV_676842r 33839 essential YOR181W 906 - TGCTGTGGTATGCCCATTGA Q|308|H silent|CAG>CAA|Q|308 LAS17 633.0 0 0 0 0 -1.4301971260183397 Q12446 0.9570760130882264 0.43117424845695496 55.75785181222165 50.0 1.0 no 13563 chrXV_676873r 33840 essential YOR181W 937 - TCTGTTAGGCAACTGTGGAA R|319|T R|319|K LAS17 633.0 0 0 0 0 -0.7694983492868718 Q12446 0.932735025882721 0.955805003643036 0.4354975521564484 0.8827047944068909 47.071720904175216 45.0 1.0 no 13564 chrXV_676874r 33841 essential YOR181W 938 - TTCTGTTAGGCAACTGTGGA R|319|T R|319|K LAS17 633.0 0 0 0 0 -0.5635622094574719 Q12446 0.932735025882721 0.955805003643036 0.4354975521564484 0.8827047944068909 49.02089605888829 45.0 1.0 no 13565 chrXV_676923 33843 essential YOR181W 984 + CCAATGCGTACCACTACTGA P|329|R P|329|L R|331|G R|331|C LAS17 633.0 0 1 0 0 0.4539649611214028 Q12446 0.9432820081710817 0.9430609941482544 0.8994590044021606 0.8926740288734436 0.7345901727676392 0.14042788743972778 0.6653198003768921 0.20859479904174805 50.030155688286975 50.0 1.0 no 13566 chrXV_676933r 33845 essential YOR181W 997 - AACACCTGAACCTTCAGTAG V|339|L V|339|I G|338|A G|338|D LAS17 633.0 0 1 0 0 -0.022128146206923882 Q12446 0.9539830088615416 0.9574310183525084 0.9499930143356324 0.9446240067481996 0.5530272126197815 0.5207741856575012 1.0 0.23077392578125 45.97180938407684 45.0 1.0 no 13567 chrXV_676963 33847 essential YOR181W 1024 + CTGCTCCTCCACCTCCGCCA A|343|G A|343|V P|344|A P|344|S LAS17 633.0 0 0 0 0 0.0001749134385864992 Q12446 0.9484469890594482 0.9504740238189696 0.9562489986419678 0.9498909711837769 0.5806369185447693 0.3492187857627869 0.6403199434280396 1.0 68.74793740287919 70.0 1.0 no 13568 chrXV_677074r 33857 essential YOR181W 1138 - TGCTGGCCCTCTTCTTCCAG A|386|P A|386|T silent|GGG>GGC|G|384 silent|GGG>GGA|G|384 LAS17 633.0 0 0 0 0 -0.11410840642551395 Q12446 0.9573720097541808 0.9523990154266356 0.30295276641845703 0.5962722301483154 63.156942637755044 60.0 1.0 no 13569 chrXV_677124r 33860 essential YOR181W 1188 - TGCATCGTAACGTTTGGTGT M|402|I M|402|I silent|ACG>ACC|T|401 silent|ACG>ACA|T|401 LAS17 633.0 0 0 0 0 0.5625601662204219 Q12446 0.9553959965705872 0.9553959965705872 0.18110091984272006 0.18110091984272006 48.956844884757004 45.0 1.0 no 13570 chrXV_677125r 33861 essential YOR181W 1189 - TTGCATCGTAACGTTTGGTG M|402|I M|402|I silent|ACG>ACC|T|401 silent|ACG>ACA|T|401 LAS17 633.0 0 0 0 0 -0.21024411542355925 Q12446 0.9553959965705872 0.9553959965705872 0.18110091984272006 0.18110091984272006 46.67901706376972 45.0 1.0 no 13571 chrXV_677182r 33862 essential YOR181W 1246 - GCTATTTGTCTGATATCCAA S|422|T S|422|N LAS17 633.0 0 0 0 0 -0.43619216930421695 Q12446 0.9512869715690612 0.9536849856376648 0.95441734790802 0.5284619927406311 45.2569748385427 35.0 1.0 no 13572 chrXV_677256 33864 essential YOR181W 1317 + CCACAAATGACTGCAGCAAC Q|441|E Q|441|* P|440|R P|440|L LAS17 633.0 0 0 0 0 -0.07383502474112175 Q12446 0.9590039849281312 0.9432820081710817 0.9430609941482544 1.0 0.0 0.0 45.396441939774896 50.0 1.0 no 13573 chrXV_677256r 33865 essential YOR181W 1320 - CCAGTTGCTGCAGTCATTTG G|447|R G|447|R LAS17 633.0 0 0 0 0 0.2421614727650376 Q12446 0.941340982913971 0.941340982913971 0.6115143895149231 0.6115143895149231 53.53012377550351 50.0 1.0 no 13574 chrXV_677355r 33874 essential YOR181W 1419 - GACTGGCCTAAAGATGCCGG Q|479|H silent|CAG>CAA|Q|479 G|478|A G|478|D LAS17 633.0 0 0 0 0 -2.39278554977457 Q12446 0.9570760130882264 0.9499930143356324 0.9446240067481996 0.23652952909469604 1.0 0.24295330047607425 52.42451354941193 60.0 1.0 yes 13575 chrXV_711892r 33876 essential YOR194C 629 + TGCATTATTAGATACGGATG A|211|G A|211|V TOA1 286.0 0 0 0 0 -0.1293148510027594 P32773 0.38474366068840027 1.0 39.74000173643856 35.0 0.0 no 13576 chrXV_711953 33877 essential YOR194C 571 - TATCTGCTCCTTTTCCTTGC Q|196|H silent|CAG>CAA|Q|196 E|195|D silent|GAG>GAA|E|195 TOA1 286.0 0 0 0 0 0.6622853071643748 P32773 0.1683283895254135 0.939126193523407 55.53123693309908 45.0 0.0 no 13577 chrXV_712022 33879 essential YOR194C 502 - TTCATCATCTATGTTTTCGA E|174|Q E|174|K D|173|H D|173|N TOA1 286.0 0 0 0 0 -0.3748673573000012 P32773 0.5562992691993713 0.8241572976112366 0.29090145230293274 0.8837877511978149 42.97201733800358 30.0 0.0 no 13578 chrXV_712117r 33881 essential YOR194C 404 + TACTAGTGGTAATACAAATG T|136|S T|136|I TOA1 286.0 0 0 0 0 0.4219341450539261 P32773 0.9346023201942444 0.23584704101085666 34.30541337915668 30.0 0.0 no 13579 chrXV_712206r 33882 essential YOR194C 315 + AACAACAACATACCGCACTC N|106|K silent|AAC>AAT|N|106 N|107|K silent|AAC>AAT|N|107 TOA1 286.0 0 0 0 0 0.06718042716101691 P32773 0.7540184259414673 0.415039598941803 43.28098494397352 45.0 0.0 no 13580 chrXV_712288 33885 essential YOR194C 236 - ACTCGCTAGAATTTACGCCG E|85|Q E|85|K E|85|D silent|GAG>GAA|E|85 TOA1 286.0 0 0 0 0 -0.85044685277536 P32773 0.5574295520782471 0.8849297165870667 0.6185249090194702 48.32646822967922 50.0 0.0 no 13581 chrXV_712344r 33887 essential YOR194C 177 + TTCAATGAAGGAAATATCAA F|60|L silent|TTC>TTT|F|60 TOA1 286.0 0 0 0 0 0.7458016926233102 P32773 0.2879908382892609 1.1940399408340454 32.00504299188333 25.0 0.0 no 13582 chrXV_719073 33889 high_effect YOR198C 973 - ATCATCAGCAACAACTTTTC D|331|H D|331|N D|330|H D|330|N BFR1 BreFeldin A Resistance 470.0 0 0 0 0 0.1842051028457992 P38934 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.1431865394115448 0.3776416182518005 0.09419988095760344 0.3194403648376465 41.562876619992146 35.0 0.0 no 13583 chrXV_719077 33890 high_effect YOR198C 969 - TCAGCAACAACTTTTCTGGC D|330|H D|330|N A|329|P A|329|T BFR1 BreFeldin A Resistance 470.0 0 0 0 0 -0.42801033472727823 P38934 0.9486550092697144 0.956179976463318 0.9573720097541808 0.9523990154266356 0.09419988095760344 0.3194403648376465 0.27105075120925903 0.5646587014198303 47.17964798060524 45.0 0.0 no 13584 chrXV_719082 33891 high_effect YOR198C 964 - AACAACTTTTCTGGCAGGCT V|328|L V|328|I V|327|L V|327|I BFR1 BreFeldin A Resistance 470.0 0 0 0 0 -0.4165620217526223 P38934 0.9539830088615416 0.9574310183525084 0.9539830088615416 0.9574310183525084 0.6101803779602051 0.6514882445335388 0.10059153288602828 0.70393967628479 49.06709430734225 45.0 0.0 no 13585 chrXV_719143 33893 high_effect YOR198C 903 - TTCTTTGGTTTCACATAAGT K|307|N silent|AAG>AAA|K|307 BFR1 BreFeldin A Resistance 470.0 0 0 0 0 0.3735449415439782 P38934 0.9355990290641784 0.4103204607963562 42.69160784523956 30.0 0.0 no 13586 chrXV_719144 33894 high_effect YOR198C 902 - TCTTTGGTTTCACATAAGTT K|307|N silent|AAG>AAA|K|307 BFR1 BreFeldin A Resistance 470.0 0 0 0 0 0.4914948900550446 P38934 0.9355990290641784 0.4103204607963562 42.69160784523956 30.0 0.0 no 13587 chrXV_719193 33896 high_effect YOR198C 853 - GGCACCGATTTCATAAGTGA A|291|P A|291|T G|290|A G|290|D BFR1 BreFeldin A Resistance 470.0 0 0 0 0 -1.0114552973000452 P38934 0.9573720097541808 0.9523990154266356 0.9499930143356324 0.9446240067481996 0.16757750511169436 0.7663478851318359 0.8212609887123108 0.742853045463562 47.72711481181966 45.0 0.0 no 13588 chrXV_719197r 33898 high_effect YOR198C 846 + CCAGCCTTCACTTATGAAAT P|283|R P|283|L A|284|G A|284|V BFR1 BreFeldin A Resistance 470.0 0 0 0 0 0.2749410659629957 P38934 0.9432820081710817 0.9430609941482544 0.9484469890594482 0.9504740238189696 0.12650485336780548 1.0 0.0 0.0 46.34080079957039 40.0 0.0 no 13589 chrXV_719276r 33899 high_effect YOR198C 767 + ACAAAGATTATCCAAACTTT Q|257|E Q|257|* BFR1 BreFeldin A Resistance 470.0 0 1 0 0 1.0532068100417022 P38934 0.9590039849281312 1.0 35.607316504700634 25.0 0.0 no 13590 chrXV_719397 33900 high_effect YOR198C 649 - TTCGTCACGCTTCTTGTACA E|223|Q E|223|K D|222|H D|222|N BFR1 BreFeldin A Resistance 470.0 0 0 0 0 -0.1803828632069242 P38934 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.5420121550559998 0.8343194723129272 0.009730532765388487 0.027412913739681244 50.83575917884003 45.0 0.0 no 13591 chrXV_719581 33901 high_effect YOR198C 465 - GCATCAACAGACTTTCTGAT A|162|P A|162|T D|161|H D|161|N BFR1 BreFeldin A Resistance 470.0 0 1 0 0 -0.15176988698210792 P38934 0.9573720097541808 0.9523990154266356 0.9486550092697144 0.956179976463318 0.1721794754266739 0.6689224243164062 0.046648196876049035 0.18110071122646326 44.78344606434803 40.0 0.0 no 13592 chrXV_719810r 33903 high_effect YOR198C 233 + TCACGACTCTATTAAGCAAT H|79|Q silent|CAC>CAT|H|79 H|79|D H|79|Y BFR1 BreFeldin A Resistance 470.0 0 1 0 0 1.3405705828482937 P38934 0.9588389992713928 0.9473130106925964 0.9489949941635132 0.35978183150291443 0.6369512677192688 0.05961330980062485 40.77224438456096 35.0 0.0 no 13593 chrXV_719825 33905 high_effect YOR198C 221 - AGTCGTGAATGTTGCTTCTA D|80|H D|80|N BFR1 BreFeldin A Resistance 470.0 0 1 0 0 -0.0412685732005211 P38934 0.9486550092697144 0.956179976463318 0.047244518995285034 0.3953846096992493 47.10295385689382 40.0 0.0 no 13594 chrXV_719895 33907 high_effect YOR198C 151 - TAACTTCTTACGTTCTTGTT K|56|N silent|AAG>AAA|K|56 K|55|N silent|AAG>AAA|K|55 BFR1 BreFeldin A Resistance 470.0 0 0 0 0 -0.7026424642421538 P38934 0.9355990290641784 0.9355990290641784 0.5059965252876282 0.25297245383262634 42.42244285137025 30.0 0.0 no 13595 chrXV_719898 33909 high_effect YOR198C 148 - CTTCTTACGTTCTTGTTGGG K|55|N silent|AAG>AAA|K|55 BFR1 BreFeldin A Resistance 470.0 0 0 0 0 0.5155977616639543 P38934 0.9355990290641784 0.25297245383262634 49.14040787662833 45.0 0.0 no 13596 chrXV_720036 33912 high_effect YOR198C 10 - GCGCTTGAACTTGTGTTGTT K|9|N silent|AAG>AAA|K|9 R|10|P R|10|H BFR1 BreFeldin A Resistance 470.0 0 0 0 0 0.846797018482278 P38934 0.9355990290641784 0.9099509716033936 0.9570810198783876 0.09815201163291933 0.20666050910949707 0.14798019826412198 50.22906424570101 45.0 0.0 no 13597 chrXV_723034 33914 essential YOR204W 123 + AACAACAACGGCGGCTACAA N|42|K silent|AAC>AAT|N|42 N|43|K silent|AAC>AAT|N|43 DED1 Defines Essential Domain 604.0 0 1 0 0 -0.6316864518325939 P06634 0.9038139581680298 0.917255163192749 44.67310637264643 50.0 1.0 no 13598 chrXV_723091 33919 essential YOR204W 180 + CGTCGTGGTGGTTACGGCAA R|62|G R|62|C DED1 Defines Essential Domain 604.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.44378137008908375 P06634 0.5756807327270508 0.18379876017570496 54.26589863150804 60.0 1.0 no 13599 chrXV_723192r 33925 essential YOR204W 284 - CCTTTTCGTTTCTTGGAGCT K|101|N silent|AAG>AAA|K|101 E|100|Q E|100|K DED1 Defines Essential Domain 604.0 0 0 0 0 0.6091928797135833 P06634 0.17717239260673526 0.5398295521736145 0.7465161085128784 53.448278136885904 45.0 1.0 no 13600 chrXV_723247r 33927 essential YOR204W 339 - ATACCAGAAGATTGGAAATT G|119|A G|119|D G|119|R G|119|S DED1 Defines Essential Domain 604.0 0 0 0 0 0.0744685116009739 P06634 0.050990622490644455 0.012444617226719856 0.005653791595250368 0.027036750689148903 36.953161102663216 30.0 1.0 no 13601 chrXV_723279 33928 essential YOR204W 368 + TAACTACGATGATATTCCAG N|124|K silent|AAC>AAT|N|124 Y|125|* silent|TAC>TAT|Y|125 DED1 Defines Essential Domain 604.0 0 0 0 0 -0.5004361779215141 P06634 1.0 39.18520285429764 35.0 1.0 no 13602 chrXV_723538 33937 essential YOR204W 627 + TCTCCTCAACCAGAGTCTCA P|211|A P|211|S S|210|C S|210|F DED1 Defines Essential Domain 604.0 0 1 0 0 -0.7863750771826008 P06634 0.7676801681518555 0.6920255422592163 0.1851106733083725 0.7087969183921814 54.56217383427696 50.0 1.0 no 13603 chrXV_723558 33939 essential YOR204W 647 + AGGCTCCTTTTACCAAAGAA silent|GGC>GGG|G|217 silent|GGC>GGT|G|217 S|218|C S|218|F DED1 Defines Essential Domain 604.0 0 0 1 Series([], Name: modification, dtype: object) 0 0.6209057338208785 P06634 0.18771742284297946 0.7047845721244812 46.25020435114522 40.0 1.0 no 13604 chrXV_723582 33940 essential YOR204W 671 + CTACCCAACTGCTGTCATTA Y|225|* silent|TAC>TAT|Y|225 P|226|A P|226|S DED1 Defines Essential Domain 604.0 0 0 0 0 0.2020736848229267 P06634 0.04284533858299256 0.0861927941441536 50.54651152923861 45.0 1.0 no 13605 chrXV_723627r 33942 essential YOR204W 719 - TCTTGGCTTCATCGAAAATT K|246|N silent|AAG>AAA|K|246 A|245|P A|245|T DED1 Defines Essential Domain 604.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.6049147280534319 P06634 0.013581081293523313 0.007880942896008492 0.006797512527555227 0.8751000165939331 41.95919693287635 35.0 1.0 no 13606 chrXV_723670 33944 essential YOR204W 759 + GTCAAGGCCTGCGTCGTCTA silent|GTC>GTG|V|254 silent|GTC>GTT|V|254 DED1 Defines Essential Domain 604.0 0 0 0 0 -0.7209863428861891 P06634 58.854079404723336 60.0 1.0 no 13607 chrXV_723711r 33946 essential YOR204W 803 - CACGTTCAATTTCTCTTAGT R|274|P R|274|H E|273|Q E|273|K DED1 Defines Essential Domain 604.0 0 0 0 0 -0.0261174243504793 P06634 0.038485947996377945 0.03706587105989456 0.05495556071400642 0.058870449662208564 -0.6014000177383423 -0.7802000045776367 44.17431389307393 35.0 1.0 no 13608 chrXV_723700r 33947 essential YOR204W 792 - TCTCTTAGTTGGTTACCAAT R|270|T R|270|K E|271|Q E|271|K DED1 Defines Essential Domain 604.0 0 0 0 0 -1.0861122139808796 P06634 0.016772584989666942 0.1718193292617798 0.589440643787384 0.4228604137897492 0.27140000462532043 -0.10159999877214433 46.16768464959324 35.0 1.0 no 13609 chrXV_723982 33954 essential YOR204W 1071 + GACTACATCTTTTTGTCTGT D|358|E silent|GAC>GAT|D|358 Y|359|* silent|TAC>TAT|Y|359 DED1 Defines Essential Domain 604.0 0 0 0 0 0.34334125920762404 P06634 0.2593044638633728 45.68425656229414 35.0 1.0 no 13610 chrXV_724076r 33955 essential YOR204W 1168 - TGCAGACAATAGATCCAATA A|396|P A|396|T L|394|F silent|TTG>TTA|L|394 DED1 Defines Essential Domain 604.0 0 0 0 0 0.21913406327873106 P06634 0.05963874608278275 0.3882710039615631 0.007781769149005412 4.065999984741212 0.6033999919891357 8.639200210571289 40.6500669765677 35.0 1.0 no 13611 chrXV_724211r 33958 essential YOR204W 1303 - GGCACGTTCTCTCTCAGATT A|441|P A|441|T R|440|P R|440|H DED1 Defines Essential Domain 604.0 0 0 0 0 -1.3129315999100406 P06634 0.022961465641856197 0.0194492656737566 0.2420567870140076 0.37459248304367065 5.355599880218506 1.8220000267028809 53.92000156451519 50.0 1.0 no 13612 chrXV_724206r 33959 essential YOR204W 1298 - GTTCTCTCTCAGATTGGGTA E|439|Q E|439|K R|438|T R|438|K DED1 Defines Essential Domain 604.0 0 0 0 0 0.18335256894556248 P06634 0.008202831260859966 0.05960471928119659 0.006869799457490444 0.019289184361696243 51.930951683334904 45.0 1.0 no 13613 chrXV_724212r 33960 essential YOR204W 1304 - AGGCACGTTCTCTCTCAGAT A|441|P A|441|T R|440|P R|440|H DED1 Defines Essential Domain 604.0 0 0 0 0 -0.012546264881260566 P06634 0.022961465641856197 0.0194492656737566 0.2420567870140076 0.37459248304367065 5.355599880218506 1.8220000267028809 53.74945842114949 50.0 1.0 no 13614 chrXV_724248 33965 essential YOR204W 1337 + ATCTGGTGCCGCTACTTTAT S|447|C S|447|F DED1 Defines Essential Domain 604.0 0 1 0 0 0.7496395951878441 P06634 0.059527948498725884 0.007665265351533891 0.26739999651908875 -0.31700000166893005 52.86083814830039 45.0 1.0 no 13615 chrXV_727616r 33966 essential YOR206W 107 - GATCAGTTTTGTTGCCACGA D|42|H D|42|N NOC2 NucleOlar Complex associated 710.0 0 1 0 0 0.9040105469480064 P39744 0.11763811111450195 0.4786340892314911 50.633788934762144 45.0 1.0 no 13616 chrXV_727938r 33972 essential YOR206W 429 - TGACTATCAATTCCATCCAA S|149|T S|149|N NOC2 NucleOlar Complex associated 710.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.03135373102192801 P39744 0.41380923986434937 0.3533380925655365 43.956926682326575 35.0 1.0 no 13617 chrXV_727875r 33973 essential YOR206W 366 - TCCAAATACTTATAAAATTC L|128|F silent|TTG>TTA|L|128 E|129|Q E|129|K NOC2 NucleOlar Complex associated 710.0 0 0 0 0 1.1253895005886037 P39744 0.02016475610435009 0.6257467865943909 1.0 31.218563205607325 20.0 1.0 no 13618 chrXV_728204r 33974 essential YOR206W 695 - AGACCATGAACATCAATTCG V|238|L V|238|I M|237|I M|237|I NOC2 NucleOlar Complex associated 710.0 0 0 0 0 0.8945172454852699 P39744 0.099078968167305 0.13947206735610962 0.057407740503549576 0.057407740503549576 41.08659853264533 40.0 1.0 no 13619 chrXV_727933r 33975 essential YOR206W 424 - ATCAATTCCATCCAATGGAT D|148|H D|148|N NOC2 NucleOlar Complex associated 710.0 0 1 0 0 -1.6734006428000991 P39744 0.07381724566221237 0.5088409781455994 44.59728486774816 35.0 1.0 no 13620 chrXV_728237 33976 essential YOR206W 725 + ACCACAAGCGATTCAAAAGA P|243|R P|243|L P|243|A P|243|S NOC2 NucleOlar Complex associated 710.0 0 0 0 0 0.0619319600657146 P39744 0.0 0.0 0.0 0.0 40.95447228027723 40.0 1.0 no 13621 chrXV_728238r 33977 essential YOR206W 729 - GCCATCTTTTGAATCGCTTG M|249|I M|249|I A|250|P A|250|T NOC2 NucleOlar Complex associated 710.0 0 0 0 0 -0.19787302951764416 P39744 0.3823571801185608 0.3823571801185608 0.0578836239874363 0.2961026728153229 49.10118668237475 45.0 1.0 no 13622 chrXV_728260r 33978 essential YOR206W 751 - GCCTTTTACAATCTTGTATG G|257|R G|257|S G|257|A G|257|D NOC2 NucleOlar Complex associated 710.0 0 0 0 0 -0.10697094657608652 P39744 0.2763004302978516 0.8185096979141235 0.43512406945228577 0.6333447098731995 44.017170017042474 35.0 1.0 no 13623 chrXV_728266 33979 essential YOR206W 754 + ACAAGATTGTAAAAGGCGCA Y|252|* silent|TAC>TAT|Y|252 NOC2 NucleOlar Complex associated 710.0 0 0 0 0 1.4251155772112385 P39744 41.04623357712319 40.0 1.0 no 13624 chrXV_728262r 33980 essential YOR206W 753 - GCGCCTTTTACAATCTTGTA G|257|A G|257|D A|258|P A|258|T NOC2 NucleOlar Complex associated 710.0 0 0 0 0 1.0993637531685445 P39744 0.43512406945228577 0.6333447098731995 0.3211657404899597 0.6648724675178528 48.84168426590736 40.0 1.0 no 13625 chrXV_728438 33985 essential YOR206W 926 + ATCATACAGAAGGATCTTAA S|310|* S|310|L Y|311|* silent|TAC>TAT|Y|311 NOC2 NucleOlar Complex associated 710.0 0 0 0 0 -3.377042739763409 P39744 0.16543994843959808 37.15826053490901 30.0 1.0 yes 13626 chrXV_728545r 33986 essential YOR206W 1036 - AGACTTCTTGAACTCTTTGG K|351|N silent|AAG>AAA|K|351 K|350|N silent|AAG>AAA|K|350 NOC2 NucleOlar Complex associated 710.0 0 0 0 0 -1.066040691841955 P39744 0.3789719939231873 0.6550638675689697 43.72109025549821 40.0 1.0 no 13627 chrXV_728782r 33988 essential YOR206W 1273 - TTCTGCGGAATTAATTTTAC E|431|Q E|431|K A|430|P A|430|T NOC2 NucleOlar Complex associated 710.0 0 0 0 0 0.6971655424559269 P39744 0.06192925944924355 0.057205036282539375 38.39656559792087 30.0 1.0 no 13628 chrXV_728930 33991 essential YOR206W 1418 + CCCATTGGTTCAGGTTACTT P|474|R P|474|L P|474|A P|474|S NOC2 NucleOlar Complex associated 710.0 0 0 0 0 -1.1354024472392592 P39744 0.0 0.0 0.0 0.0 53.468824174952886 45.0 1.0 no 13629 chrXV_728931 33992 essential YOR206W 1419 + CCATTGGTTCAGGTTACTTT P|474|R P|474|L NOC2 NucleOlar Complex associated 710.0 0 0 0 0 0.28893952289718955 P39744 0.0 0.0 49.86949894732396 40.0 1.0 no 13630 chrXV_728931r 33993 essential YOR206W 1422 - CCCAAAGTAACCTGAACCAA L|480|F silent|TTG>TTA|L|480 G|481|R G|481|S NOC2 NucleOlar Complex associated 710.0 0 0 0 0 0.3388476831511699 P39744 0.042322564870119095 0.0 0.0 45.41679495451149 45.0 1.0 no 13631 chrXV_730856r 33996 essential YOR207C 2579 + AAACGTCCAAACTCAATATA N|861|K silent|AAC>AAT|N|861 silent|GTC>GTG|V|862 silent|GTC>GTT|V|862 RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 0.26602854796993325 P22276 0.9242896437644958 36.51935222941472 30.0 0.0 no 13632 chrXV_731030 34003 essential YOR207C 2408 - TCATACCACCGATGATATCT M|809|I M|809|I G|808|A G|808|D RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 -0.07134506280050806 P22276 0.2576291859149933 0.2576291859149933 0.4672275185585022 0.3873972892761231 46.630920670551866 40.0 0.0 no 13633 chrXV_731110r 34006 essential YOR207C 2325 + TCATCCATCGATAGAGGTTT S|776|* S|776|L S|777|C S|777|F RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 -1.1515723577042305 P22276 0.0043501099571585655 0.0019655036740005016 0.0008129057823680341 47.36239046153327 40.0 0.0 no 13634 chrXV_731189r 34007 essential YOR207C 2246 + ACCTGCTGGTCAAAATGCTA P|750|R P|750|L P|750|A P|750|S RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 -1.3012811508306683 P22276 0.009678391739726068 0.01343054696917534 0.10299848020076753 0.05224582552909851 48.19506863062026 45.0 0.0 no 13635 chrXV_731223 34008 essential YOR207C 2215 - ATCGATCAATTCAATTGTTT D|745|H D|745|N L|743|F silent|TTG>TTA|L|743 RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 -0.1920105775715396 P22276 0.3812107443809509 1.0 0.09807810932397842 37.924322526488474 25.0 0.0 no 13636 chrXV_731342r 34010 essential YOR207C 2093 + TAACACATATCAATGTGCGA N|699|K silent|AAC>AAT|N|699 T|700|R T|700|I RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 0.5600924887891329 P22276 0.0 0.0 0.0 0.3851999938488007 0.2978000044822693 39.828620275521025 35.0 0.0 no 13637 chrXV_731341r 34011 essential YOR207C 2094 + AACACATATCAATGTGCGAT N|699|K silent|AAC>AAT|N|699 T|700|R T|700|I RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 -0.13814105465629672 P22276 0.0 0.0 0.0 0.3851999938488007 0.2978000044822693 40.343017941501216 35.0 0.0 no 13638 chrXV_731252r 34012 essential YOR207C 2183 + GACTTATCCACAACAGCCAA T|729|S T|729|I RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 0.20204743040043693 P22276 0.049608968198299415 0.09825942665338516 47.6890304928769 45.0 0.0 no 13639 chrXV_731348 34014 essential YOR207C 2090 - CACATTGATATGTGTTACGA C|703|S C|703|Y RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 0.004660130869290152 P22276 0.1025964692234993 0.001212156261317432 40.90154133704954 35.0 0.0 no 13640 chrXV_731349 34015 essential YOR207C 2089 - ACATTGATATGTGTTACGAG C|703|S C|703|Y RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 -0.2406153339442568 P22276 0.1025964692234993 0.001212156261317432 39.59223647322421 35.0 0.0 no 13641 chrXV_731401r 34016 essential YOR207C 2034 + ACAATTTTAGGTGCTGTTGC T|679|R T|679|I RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 -0.06916071401506943 P22276 0.002513234503567219 0.0028511187992990017 46.65747041129248 40.0 0.0 no 13642 chrXV_731605 34018 essential YOR207C 1833 - CCATCAGAAACAATGATTAA G|618|R G|618|S D|617|H D|617|N RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 0.9427134851979068 P22276 0.05591553077101708 0.0616263821721077 0.04635229334235191 1.0 35.55691014109158 30.0 0.0 no 13643 chrXV_731605r 34019 essential YOR207C 1830 + CCATTAATCATTGTTTCTGA P|611|R P|611|L RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 0.3689098226212317 P22276 0.0 0.0 42.14818099533153 30.0 0.0 no 13644 chrXV_731651 34020 essential YOR207C 1787 - TTGCAATATGAACTGCCATT A|602|P A|602|T RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 -1.3958171139076403 P22276 0.015571716241538525 0.02162081003189087 43.4431745082186 35.0 0.0 no 13645 chrXV_731734 34021 essential YOR207C 1704 - AACTGAGTAACGAATTTTGT Q|574|H silent|CAG>CAA|Q|574 RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 0.5541175599662836 P22276 0.11799170076847075 36.808363183404715 30.0 0.0 no 13646 chrXV_731735 34022 essential YOR207C 1703 - ACTGAGTAACGAATTTTGTT Q|574|H silent|CAG>CAA|Q|574 RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 -0.3650851144576245 P22276 0.11799170076847075 38.32263920294946 30.0 0.0 no 13647 chrXV_731929 34023 essential YOR207C 1509 - AGACCACACGCCTCACCTTC G|509|A G|509|D G|509|R G|509|S RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 -1.7748032025085014 P22276 0.0 0.0 0.0 0.0 57.92053686081346 60.0 0.0 no 13648 chrXV_731939r 34025 essential YOR207C 1496 + TGCAGATACTCCAGAAGGTG A|500|G A|500|V RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 0.20835513513483306 P22276 0.5232542157173157 0.17044222354888916 48.083302050128744 50.0 0.0 no 13649 chrXV_731974r 34026 essential YOR207C 1461 + GCATTACAACCTTCTCAATT A|488|G A|488|V Q|490|E Q|490|* RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 0.4825959809963377 P22276 0.032908227294683456 0.01014882419258356 0.008578887209296227 44.34093397536833 35.0 0.0 no 13650 chrXV_732042 34027 essential YOR207C 1396 - TCTTGTCATCATACCCAATG R|472|T R|472|K M|470|I M|470|I RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 -0.055970059009159016 P22276 0.0035749953240156174 0.2368316352367401 0.010977407917380331 0.010977407917380331 46.737993874857295 40.0 0.0 no 13651 chrXV_732132r 34031 essential YOR207C 1303 + GAGCTATCTCAACCGGTAAT A|436|G A|436|V RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 -0.3271718613102663 P22276 0.006973973475396633 0.007055216468870641 47.25764886167975 45.0 0.0 no 13652 chrXV_732208 34032 essential YOR207C 1230 - TCGTATTCCATAGCCCTATT D|417|H D|417|N RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 -0.7855351659120476 P22276 0.017595110461115837 0.13077230751514435 52.05503471505914 40.0 0.0 no 13653 chrXV_732349 34033 essential YOR207C 1089 - TCTCTATCATCAATCATCTT R|369|T R|369|K D|370|H D|370|N RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 -0.4360152223240473 P22276 0.009532635100185871 0.9933982491493224 0.0 0.0 42.55877581742152 30.0 0.0 no 13654 chrXV_732350 34034 essential YOR207C 1088 - CTCTATCATCAATCATCTTA R|369|T R|369|K D|368|H D|368|N RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 0.02178914751925526 P22276 0.009532635100185871 0.9933982491493224 0.0 0.0 40.9852613020679 30.0 0.0 no 13655 chrXV_732419 34035 essential YOR207C 1019 - AAGCCTTTTCTCTAAAGTCA A|346|P A|346|T K|345|N silent|AAG>AAA|K|345 RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 0.14870640151432835 P22276 0.08368845283985138 0.17045241594314575 0.0026830877177417283 44.75568210404606 35.0 0.0 no 13656 chrXV_732450 34036 essential YOR207C 988 - AGTCAAATGTGCAATAACCG L|335|F silent|TTG>TTA|L|335 RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 -1.6211339908249525 P22276 0.051688551902771 40.84846066398581 40.0 0.0 no 13657 chrXV_732479 34038 essential YOR207C 959 - TGGCCTCTATACCCTCTTGC A|326|P A|326|T E|325|D silent|GAG>GAA|E|325 RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 -1.3271662712421006 P22276 0.03575502708554268 0.2372589111328125 1.0 59.515032194064425 55.00000000000001 0.0 no 13658 chrXV_732490r 34040 essential YOR207C 945 + AAACTGACTATCCTGCAAGA L|317|V silent|CTG>TTG|L|317 RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 0.4911645755884682 P22276 0.3087056279182434 42.822063620256024 40.0 0.0 no 13659 chrXV_732913r 34043 essential YOR207C 522 + AACGAGTGTCCGTTGGATCC N|175|K silent|AAC>AAT|N|175 RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 0.6239142633016732 P22276 0.6285281181335449 52.662129664955906 55.00000000000001 0.0 no 13660 chrXV_732950 34044 essential YOR207C 488 - TCGATTCATCAGCATCATAT silent|TCG>TCC|S|169 silent|TCG>TCA|S|169 E|168|Q E|168|K RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 -0.2565894458859881 P22276 0.26993343234062195 0.42147934436798096 44.24703775981516 35.0 0.0 no 13661 chrXV_733064r 34046 essential YOR207C 371 + ATACTCTGCACCAATCTACG Y|125|* silent|TAC>TAT|Y|125 S|126|C S|126|F RET1 Reduced Efficiency of Termination 1149.0 1 Series([], Name: modification, dtype: object) 0 0 0 -2.8508940850279165 P22276 0.003843826707452536 0.0022426992654800415 46.60700481745033 45.0 0.0 yes 13662 chrXV_733101r 34048 essential YOR207C 334 + TGACTCCGCCTCATGAGTGT T|113|S T|113|I P|114|A P|114|S RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 -0.6076643135310509 P22276 0.01314498484134674 1.0 0.05996425822377205 0.09389603137969972 56.7499812694261 55.00000000000001 0.0 no 13663 chrXV_733171 34050 essential YOR207C 267 - ACGTACTTCAGGTAGAATTC V|96|L V|96|I K|94|N silent|AAG>AAA|K|94 RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 -0.8578165208648748 P22276 0.7731587886810303 0.20794112980365756 0.11549341678619385 43.06541237553654 40.0 0.0 no 13664 chrXV_733291r 34052 essential YOR207C 144 + CCAGCATTCTTGAAGGTTAA P|49|R P|49|L A|50|G A|50|V RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 -1.1753002932808063 P22276 0.008444461040198803 0.0035115082282572985 0.13678771257400513 0.19873641431331635 45.56909742951683 40.0 0.0 no 13665 chrXV_733400r 34055 essential YOR207C 35 + ACATAAGCATGTGAAAGACG H|13|D H|13|Y RET1 Reduced Efficiency of Termination 1149.0 0 0 0 0 0.7364549939347994 P22276 38.14264522752961 40.0 0.0 no 13666 chrXV_749341r 34056 essential YOR217W 43 - TCTGGATGTTGACGATCTTA R|21|T R|21|K RFC1 Replication Factor C 861.0 0 0 0 0 -0.26465107004747346 P38630 0.932735025882721 0.955805003643036 0.5076809525489807 0.9399407505989076 45.010709214104565 40.0 1.0 no 13667 chrXV_749358 34057 essential YOR217W 57 + TCCAGACCTACGAGACAGGT silent|TCC>TCG|S|20 silent|TCC>TCT|S|20 S|20|C S|20|F RFC1 Replication Factor C 861.0 0 0 0 0 -0.6161222422220538 P38630 0.945252001285553 0.9294660091400146 0.05403639003634453 0.052659876644611366 52.9592422142502 55.00000000000001 1.0 no 13668 chrXV_749364r 34058 essential YOR217W 66 - GACGAACCCACCTGTCTCGT silent|TCG>TCC|S|28 silent|TCG>TCA|S|28 G|27|A G|27|D RFC1 Replication Factor C 861.0 0 0 0 0 0.2300377621352996 P38630 0.9499930143356324 0.9446240067481996 0.7648700475692749 0.6252813935279846 56.4297858976758 60.0 1.0 no 13669 chrXV_749434r 34059 essential YOR217W 136 - CATCTTCTTTGGTGTTTTAT K|51|N silent|AAG>AAA|K|51 K|50|N silent|AAG>AAA|K|50 RFC1 Replication Factor C 861.0 0 1 0 0 0.3821949805703732 P38630 0.9355990290641784 0.9355990290641784 0.5052176713943481 0.4997434914112091 44.579749521944905 30.0 1.0 no 13670 chrXV_749457r 34060 essential YOR217W 159 - ACATCAATTACATTACTTAC V|60|L V|60|I D|59|H D|59|N RFC1 Replication Factor C 861.0 0 1 0 0 -0.7190085917693273 P38630 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 0.3180672228336334 0.22059227526187894 0.11703075468540193 0.476255714893341 35.424191133245245 25.0 1.0 no 13671 chrXV_749506 34062 essential YOR217W 205 + AGCTACCTCTTCCCGCTAAG L|70|V silent|CTA>TTA|L|70 P|71|A P|71|S RFC1 Replication Factor C 861.0 0 1 0 0 0.5228696863765959 P38630 0.9512209892272948 0.9562489986419678 0.9498909711837769 0.30533015727996826 0.752677321434021 0.7221797704696655 56.36870080935847 55.00000000000001 1.0 no 13672 chrXV_749594 34064 essential YOR217W 293 + AGACTCGGCTTCGAATATTA D|99|E silent|GAC>GAT|D|99 S|100|W S|100|L RFC1 Replication Factor C 861.0 0 0 0 0 0.7571256116504546 P38630 0.9532920122146606 0.9288619756698608 0.9298099875450134 1.0 0.015492519363760946 0.2726215124130249 44.173011723817346 40.0 1.0 no 13673 chrXV_749751r 34066 essential YOR217W 453 - AAACAATTTGGCTTTCCTTC C|157|S C|157|Y RFC1 Replication Factor C 861.0 0 0 0 0 0.352773125290801 P38630 0.9421560168266296 0.9290120005607604 0.0 0.0 43.25715630186004 35.0 1.0 no 13674 chrXV_749778 34067 essential YOR217W 477 + GGTCTAACAATTGTCTTCAC L|161|V silent|CTA>TTA|L|161 RFC1 Replication Factor C 861.0 0 0 0 0 -1.654697773633898 P38630 0.9512209892272948 0.01861879602074623 2.14739990234375 43.6542000542276 40.0 1.0 no 13675 chrXV_749991 34074 essential YOR217W 690 + GCTGGGATGCCTGCTGAAGG A|231|G A|231|V RFC1 Replication Factor C 861.0 0 0 0 0 0.33820379887539936 P38630 0.9484469890594482 0.9504740238189696 0.09858185797929764 0.07392031699419023 57.459246308425854 65.0 1.0 no 13676 chrXV_750073r 34077 essential YOR217W 775 - AACAAGCAATTCTGCTTCTT V|265|L V|265|I L|263|F silent|TTG>TTA|L|263 RFC1 Replication Factor C 861.0 0 0 0 0 0.7681830536443964 P38630 0.9539830088615416 0.9574310183525084 0.9587849974632264 0.2326987683773041 0.1214706152677536 0.0352744460105896 43.31019633825696 35.0 1.0 no 13677 chrXV_750126 34078 essential YOR217W 825 + GCAGCCACTAGAGTTTCTGG A|276|G A|276|V A|277|G A|277|V RFC1 Replication Factor C 861.0 0 0 0 0 0.3134868926243546 P38630 0.9484469890594482 0.9504740238189696 0.9484469890594482 0.9504740238189696 0.33010098338127136 0.2698781192302704 0.30558592081069946 0.22946786880493164 55.00457129736492 55.00000000000001 1.0 no 13678 chrXV_750213 34080 essential YOR217W 912 + ACGAATCTACAACAGGTCTG T|305|R T|305|M L|307|V silent|CTA>TTA|L|307 RFC1 Replication Factor C 861.0 0 0 0 0 0.09644285810306644 P38630 0.9476869702339172 0.9502379894256592 0.9512209892272948 0.006188421975821257 0.002965756691992283 0.057524025440216064 -0.4995999932289124 -0.07660000026226044 2.361799955368042 42.686540662945106 45.0 1.0 no 13679 chrXV_750345 34082 essential YOR217W 1044 + GCAATGTTATACGGTCCTCC A|349|G A|349|V RFC1 Replication Factor C 861.0 0 0 0 0 -0.18078730675070576 P38630 0.9484469890594482 0.9504740238189696 0.002848261035978794 1.0 1.924000024795532 -1.180799961090088 52.29772496939336 50.0 1.0 no 13680 chrXV_750363r 34083 essential YOR217W 1065 - GCAGTTGTCTTCCCAATACC A|362|P A|362|T RFC1 Replication Factor C 861.0 0 0 0 0 -0.8072507667038067 P38630 0.9573720097541808 0.9523990154266356 0.0 0.0 5.158400058746338 -1.2519999742507937 54.98443000462163 50.0 1.0 no 13681 chrXV_750469r 34084 essential YOR217W 1171 - ATCAAGAGCGTTTTTAACAC D|397|H D|397|N RFC1 Replication Factor C 861.0 0 0 0 0 -0.2200581200783324 P38630 0.9486550092697144 0.956179976463318 0.03725460171699524 0.7148112058639526 1.4442000389099119 0.9043999910354614 40.01923695999306 35.0 1.0 no 13682 chrXV_750614r 34086 essential YOR217W 1316 - TACGACAAAACTGTGCCAGC R|445|P R|445|H C|444|S C|444|Y RFC1 Replication Factor C 861.0 0 0 0 0 1.0271160492605205 P38630 0.9099509716033936 0.9570810198783876 0.9421560168266296 0.9290120005607604 0.00826810672879219 0.009233765304088593 0.017115334048867226 0.0014384331880137324 3.3905999660491943 0.5616000294685364 1.0757999420166016 10.970199584960938 45.923928158139006 50.0 1.0 no 13683 chrXV_750798r 34087 essential YOR217W 1500 - ATCAACCTATCAATGACATT L|506|F silent|TTG>TTA|L|506 R|505|S silent|AGG>AGA|R|505 RFC1 Replication Factor C 861.0 0 0 0 0 0.055637425799193035 P38630 0.9587849974632264 0.9087679982185364 0.012276330962777138 0.6576914787292479 7.845799922943115 0.6168000102043152 39.78007622084607 30.0 1.0 no 13684 chrXV_750827 34088 essential YOR217W 1526 + TACAAGAGGTGATATCCGCC T|510|R T|510|I RFC1 Replication Factor C 861.0 0 0 0 0 0.3065075071166073 P38630 0.9476869702339172 0.9472420215606691 0.010081727989017963 0.011878663673996924 2.0127999782562256 2.696199893951416 49.17212850948504 50.0 1.0 no 13685 chrXV_750956 34090 essential YOR217W 1655 + TGACATTGCCCATAAAATGT D|553|E silent|GAC>GAT|D|553 RFC1 Replication Factor C 861.0 0 0 0 0 -0.3847725359091408 P38630 0.9532920122146606 0.0 0.2021999955177307 42.67444840716405 35.0 1.0 no 13686 chrXV_751058 34091 essential YOR217W 1757 + TTTCACACCCCTAATGATTC F|587|L silent|TTC>TTT|F|587 T|588|R T|588|I RFC1 Replication Factor C 861.0 0 0 0 0 -0.3324928931839575 P38630 0.9387490153312684 0.9476869702339172 0.9472420215606691 0.06646491587162018 0.020269891247153282 0.03636151552200317 -0.971400022506714 6.799799919128418 -0.14720000326633453 -1.3528000116348269 47.83715686145075 40.0 1.0 no 13687 chrXV_750981 34092 essential YOR217W 1680 + GGACAAATATACTCAGACAT Q|562|E Q|562|* RFC1 Replication Factor C 861.0 0 0 0 0 -0.24672980024609345 P38630 0.9590039849281312 0.5156554579734802 1.2028000354766846 38.25740490955349 35.0 1.0 no 13688 chrXV_751098 34093 essential YOR217W 1797 + AGACCAAGCGTTTTGAAACC P|601|A P|601|S P|601|R P|601|L RFC1 Replication Factor C 861.0 0 0 0 0 0.20195938009730605 P38630 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.0 0.0 0.0 0.0 2.3752000331878658 3.885600090026856 6.283599853515625 3.291599988937378 45.216149807881315 45.0 1.0 no 13689 chrXV_751116r 34094 essential YOR217W 1818 - GCTTCCAAATGTGACTGGCC A|613|P A|613|T E|612|Q E|612|K RFC1 Replication Factor C 861.0 0 0 0 0 0.16384093904681166 P38630 0.9573720097541808 0.9523990154266356 0.956179976463318 0.9475290179252625 0.07970775663852693 0.15925519168376925 0.20550355315208435 0.10686153173446657 3.0613999366760254 2.622600078582764 0.2440000027418137 0.28839999437332153 53.638252774757404 55.00000000000001 1.0 no 13690 chrXV_751117r 34095 essential YOR217W 1819 - TGCTTCCAAATGTGACTGGC A|613|P A|613|T E|612|Q E|612|K RFC1 Replication Factor C 861.0 0 0 0 0 1.136383850531833 P38630 0.9573720097541808 0.9523990154266356 0.956179976463318 0.9475290179252625 0.07970775663852693 0.15925519168376925 0.20550355315208435 0.10686153173446657 3.0613999366760254 2.622600078582764 0.2440000027418137 0.28839999437332153 49.96848204436486 50.0 1.0 no 13691 chrXV_751121r 34096 essential YOR217W 1823 - CAACTGCTTCCAAATGTGAC V|614|L V|614|I A|613|P A|613|T RFC1 Replication Factor C 861.0 0 0 0 0 -0.16358466756653536 P38630 0.9539830088615416 0.9574310183525084 0.9573720097541808 0.9523990154266356 0.26373425126075745 0.4478362798690796 0.07970775663852693 0.15925519168376925 -0.6815999746322632 -0.5759999752044678 3.0613999366760254 2.622600078582764 44.28695490470466 45.0 1.0 no 13692 chrXV_760945 34100 essential YOR224C 301 - TACTTCCTCAAACTTGTAAG V|107|L V|107|I E|106|Q E|106|K RPB8 RNA Polymerase B 146.0 0 0 0 0 -0.9336484349314118 P20436 0.2782207131385803 0.17200453579425812 0.25192052125930786 0.21968518197536469 -1.2372000217437744 0.4875999987125397 0.10540000349283217 0.6797999739646912 -0.6007999777793884 0.6011999845504761 0.21960000693798065 -0.01860000006854534 40.22543339087042 35.0 0.0 no 13693 chrXV_761041 34104 essential YOR224C 205 - CGCAGAAGAGTCGTTAGCTG A|75|P A|75|T RPB8 RNA Polymerase B 146.0 0 0 0 0 -0.8871689397749284 P20436 0.24127091467380524 0.5398200154304504 1.8043999671936035 0.5131999850273132 48.97372326627425 55.00000000000001 0.0 no 13694 chrXV_761142 34106 essential YOR224C 104 - TATCCAAGGTTAGTTTGCAT D|41|H D|41|N L|40|F silent|TTG>TTA|L|40 RPB8 RNA Polymerase B 146.0 0 0 0 0 -0.14262950112669548 P20436 0.0 0.0 0.015535082668066025 1.3206000328063965 1.6917999982833862 2.747600078582764 46.095785370082865 35.0 0.0 no 13695 chrXV_761145r 34107 essential YOR224C 98 + GGACCAATGCAAACTAACCT D|34|E silent|GAC>GAT|D|34 Q|35|E Q|35|* RPB8 RNA Polymerase B 146.0 0 0 0 0 -0.5867764334482419 P20436 0.04612385854125023 1.0 -0.08739999681711197 -0.029999999329447743 45.06083608333592 45.0 0.0 no 13696 chrXV_774595r 34111 essential YOR232W 25 - CTTCCTAGTTGTGGCCCTAA R|14|S silent|AGG>AGA|R|14 R|14|T R|14|K MGE1 Mitochondrial GrpE 228.0 0 0 0 0 0.3054972981746334 P38523 0.9087679982185364 0.932735025882721 0.955805003643036 0.7545191049575806 0.6798190474510193 0.8828061819076538 56.34506531435125 50.0 1.0 no 13697 chrXV_774657 34112 essential YOR232W 84 + CCATCATTTACAAAGAATGT P|29|R P|29|L S|30|* S|30|L MGE1 Mitochondrial GrpE 228.0 0 0 0 0 0.2026791625278722 P38523 0.9432820081710817 0.9430609941482544 0.9298099875450134 0.4419641494750977 0.4684021174907684 0.8313637375831604 38.044517291480645 30.0 1.0 no 13698 chrXV_774908 34114 essential YOR232W 335 + TGCTTTACAGAAGTTTGCAA A|113|G A|113|V MGE1 Mitochondrial GrpE 228.0 0 1 0 0 -0.6983009021281932 P38523 0.9484469890594482 0.9504740238189696 0.022981254383921627 0.007293717470020057 0.5210000276565552 0.21699999272823334 42.709164643011825 35.0 1.0 no 13699 chrXV_774962 34115 essential YOR232W 389 + TGCTTTGAATGCTTTTAAAG A|131|G A|131|V MGE1 Mitochondrial GrpE 228.0 0 0 0 0 -1.1948846807595537 P38523 0.9484469890594482 0.9504740238189696 0.0 0.0 0.5314000248908997 1.3406000137329102 0.781000018119812 1.3259999752044678 37.870133555428474 30.0 1.0 no 13700 chrXV_775000r 34116 essential YOR232W 430 - ATACAAATCACTAATTTCCT L|149|F silent|TTG>TTA|L|149 MGE1 Mitochondrial GrpE 228.0 0 1 0 0 0.35337716189698354 P38523 0.9587849974632264 0.0 -0.05160000175237656 37.44210155178382 25.0 1.0 no 13701 chrXV_775061r 34117 essential YOR232W 491 - TTTCAATACCGTGCTTTCTT E|170|Q E|170|K MGE1 Mitochondrial GrpE 228.0 0 1 0 0 0.6192787370679499 P38523 0.956179976463318 0.9475290179252625 0.06844126433134079 0.13388681411743164 47.04220650998764 35.0 1.0 no 13702 chrXV_781000r 34122 essential YOR236W 97 - TCTGAAATACTTCATTTCAC R|39|T R|39|K DFR1 DihydroFolate Reductase 211.0 0 0 0 0 0.4251259326092207 P07807 0.91388201713562 0.9414479732513428 0.021632414311170575 1.0 37.695265194244655 30.0 1.0 no 13703 chrXV_781232 34126 essential YOR236W 326 + AAGCAATTTTAAGGAGCATC S|110|R silent|AGC>AGT|S|110 DFR1 DihydroFolate Reductase 211.0 0 0 0 0 0.20947528083685865 P07807 0.9263970255851746 0.4280432462692261 39.661731082173155 35.0 1.0 no 13704 chrXV_781297 34127 essential YOR236W 391 + TCTTCTCCATTACAGATCAT I|131|M silent|ATC>ATT|I|131 F|132|L silent|TTC>TTT|F|132 DFR1 DihydroFolate Reductase 211.0 0 0 0 0 -0.4621521511540132 P07807 0.9536030292510986 0.9417070150375366 0.22234085202217105 0.938166320323944 2.033060073852539 46.348981475673334 35.0 1.0 no 13705 chrXV_781359r 34128 essential YOR236W 456 - TCAAGGAAAGTGTCCATTGC D|159|H D|159|N DFR1 DihydroFolate Reductase 211.0 0 0 0 0 -0.1577562360205331 P07807 0.930002987384796 0.942907989025116 0.12877298891544342 0.7985337972640991 45.76706473638188 45.0 1.0 no 13706 chrXV_781376r 34130 essential YOR236W 473 - CTTCCAATTTCTTCGCATCA E|164|Q E|164|K L|163|F silent|TTG>TTA|L|163 DFR1 DihydroFolate Reductase 211.0 0 0 0 0 0.3042249923677274 P07807 0.9435089826583862 0.9307000041007996 0.9461140036582948 0.5032191276550293 0.8394360542297363 0.6763362884521484 48.920466067847826 40.0 1.0 no 13707 chrXV_792565r 34131 essential YOR244W 37 - ATCTACTGAGTTTATCTTTT D|19|H D|19|N V|18|L V|18|I ESA1 445.0 0 1 0 0 0.5680296179685032 Q08649 0.8634979724884033 1.017449975013733 1.0101200342178345 1.0162500143051147 0.09443732351064682 0.6066095232963562 0.5298938155174255 0.4789815843105316 0.7827399969100952 0.5990999937057495 -0.9186800122261048 0.4245400130748749 40.74529952801971 25.0 1.0 no 13708 chrXV_792771r 34133 essential YOR244W 243 - TCATCAGTAGCCTTTAGTTT E|88|Q E|88|K D|87|H D|87|N ESA1 445.0 0 0 0 0 0.9809172250636112 Q08649 1.0137699842453003 1.0066399574279783 0.9617130160331726 1.0142199993133545 0.4874521493911743 1.0 0.09681863337755203 0.3936398327350617 -0.5239800214767456 -0.4811399877071381 -0.30757999420166016 -0.11454000324010848 48.70334078177081 35.0 1.0 no 13709 chrXV_792992 34137 essential YOR244W 461 + GACACAAAATCCACATGAGG T|155|R T|155|I Q|156|E Q|156|* ESA1 445.0 0 1 0 0 -0.6159176605170885 Q08649 0.950892984867096 0.9730870127677916 0.9940789937973022 0.0738820731639862 0.09659422188997267 0.013905069790780544 41.25627530753911 45.0 1.0 no 13710 chrXV_793026 34138 essential YOR244W 495 + AATCTCAATCGAATCATTAT L|167|V L|167|F silent|CTC>CTG|L|167 silent|CTC>CTT|L|167 ESA1 445.0 0 0 0 0 0.0015029639813129991 Q08649 0.9284570217132568 0.8904060125350952 0.17365044355392456 0.16486085951328278 1.868939995765686 1.1334999799728394 -0.7195000052452087 4.305540084838866 35.69540676263847 25.0 1.0 no 13711 chrXV_793027 34139 essential YOR244W 496 + ATCTCAATCGAATCATTATG L|167|V L|167|F silent|CTC>CTG|L|167 silent|CTC>CTT|L|167 ESA1 445.0 0 0 0 0 0.4924947507092416 Q08649 0.9284570217132568 0.8904060125350952 0.17365044355392456 0.16486085951328278 1.868939995765686 1.1334999799728394 -0.7195000052452087 4.305540084838866 36.98342052813098 30.0 1.0 no 13712 chrXV_793086r 34140 essential YOR244W 558 - TCTTCATCAGTTAATTCAAT D|193|H D|193|N E|192|Q E|192|K ESA1 445.0 0 0 0 0 0.4936288978787131 Q08649 0.7408649921417236 0.8276820182800293 0.9569990038871764 0.9277610182762146 0.062350098043680184 0.19472426176071167 0.5886555314064026 0.9240519404411316 2.15693998336792 -0.4617399871349335 -0.08444000035524367 -0.04845999926328659 38.439748475530045 25.0 1.0 no 13713 chrXV_793080r 34141 essential YOR244W 552 - TCAGTTAATTCAATAGGATA D|191|H D|191|N ESA1 445.0 0 0 0 0 0.6256553341250256 Q08649 0.9020879864692688 0.913989007472992 0.3610848784446716 0.5103619694709778 0.6110600233078003 0.27695998549461365 35.73822894287804 25.0 1.0 no 13714 chrXV_793200r 34142 essential YOR244W 672 - TCTCTGTAGATTTCATTTCC R|230|T R|230|K D|231|H D|231|N ESA1 445.0 0 0 0 0 0.4885186215469106 Q08649 0.7971150279045105 0.9304969906806946 0.7902690172195435 0.8607339859008789 0.0 0.0 0.30870652198791504 0.5259730219841003 1.3651399612426758 -0.2237599939107895 6.890160083770753 4.240079879760741 46.39645778248166 35.0 1.0 no 13715 chrXV_793417r 34143 essential YOR244W 889 - TGCAACATTGTAACCATCCG A|303|P A|303|T V|302|L V|302|I ESA1 445.0 0 1 0 0 -5.035937143781627 Q08649 0.6339060068130493 0.6430870294570923 0.8960999846458435 0.8271949887275696 0.0 0.0 0.3105831742286682 0.04139435663819313 4.51200008392334 1.015720009803772 0.6671800017356873 0.2872999906539917 3.4599199295043945 0.8436400294303894 46.57644450156431 45.0 1.0 yes 13716 chrXV_793447 34144 essential YOR244W 916 + TAACACTACCACAATACCAA T|307|R T|307|I L|308|V silent|CTA>TTA|L|308 ESA1 445.0 0 1 0 0 -1.5362869505749752 Q08649 0.5110830068588257 0.7120519876480103 0.8126599788665771 0.0026487254071980715 0.013340122066438198 0.009062042459845543 1.8336199522018437 -1.904979944229126 2.8157799243927 40.50444698664336 35.0 1.0 no 13717 chrXV_793452 34146 essential YOR244W 921 + CTACCACAATACCAAAGGAT P|309|A P|309|S P|309|R P|309|L ESA1 445.0 0 1 0 0 -1.2606607573435862 Q08649 0.6545270085334778 0.6439070105552673 0.6202279925346375 0.6206830143928528 0.0 0.0 0.0 0.0 3.522380113601685 3.564079999923706 3.2371399402618413 2.6630001068115234 3.6670000553131104 4.343140125274658 9.07688045501709 2.102560043334961 42.265908589893506 40.0 1.0 no 13718 chrXV_793455r 34147 essential YOR244W 927 - TATCCCATCCTTTGGTATTG G|315|A G|315|E G|315|R G|315|R ESA1 445.0 0 0 0 0 0.04846245820310549 Q08649 0.7339439988136292 0.6812790036201477 0.7114220261573792 0.7114220261573792 0.0239801537245512 0.0033974535763263702 0.002392058959230781 0.002392058959230781 3.7832999229431152 2.7202999591827397 5.7179999351501465 5.7179999351501465 50.45183381085486 40.0 1.0 no 13719 chrXV_799259 34150 essential YOR249C 1453 - TTTCTCATATACATCGGATA E|490|D silent|GAG>GAA|E|490 E|490|Q E|490|K 0 0 0 0 0.11333123772130906 Q08683 0.6050681471824646 0.6065034866333008 0.8030903339385986 40.731596686248615 30.0 0.0 no 13720 chrXV_799312 34151 essential YOR249C 1400 - CTTCATAGCTAACAAGACTT E|473|Q E|473|K 0 0 0 0 0.8209568710884803 Q08683 0.3122264444828033 0.3245063424110413 40.55728749848202 35.0 0.0 no 13721 chrXV_799666 34154 essential YOR249C 1046 - CACACTCATTGAAACTTGAG C|355|S C|355|Y E|354|D silent|GAG>GAA|E|354 0 0 0 0 -0.028253479176109462 Q08683 0.6636436581611633 0.0577937625348568 1.0 39.28825187818734 40.0 0.0 no 13722 chrXV_799642r 34155 essential YOR249C 1067 + TGCAGCGATAAATTCTTTTG A|357|G A|357|V A|358|G A|358|V 0 0 0 0 0.5636705705510071 Q08683 0.12760706245899198 0.05857245996594429 0.0 0.0 40.76372004994374 35.0 0.0 no 13723 chrXV_799889 34158 essential YOR249C 823 - TCCGCTTTGTTCTTCATATG G|281|R G|281|R G|281|A G|281|E 0 0 0 0 -1.261721783674321 Q08683 0.5429959297180176 0.5429959297180176 0.7654488682746887 1.0 48.95944746954928 40.0 0.0 no 13724 chrXV_799978 34159 essential YOR249C 734 - TAACTATTGATTGTAAATGT V|251|L V|251|I 0 0 0 0 0.056637712734220386 Q08683 1.0 0.4324325919151306 32.43451919903964 20.0 0.0 no 13725 chrXV_800383r 34164 essential YOR249C 326 + TTCAATCAACAGACTAATGA S|110|* S|110|L I|111|M silent|ATC>ATT|I|111 0 0 0 0 0.07913491533700395 Q08683 0.4018559455871582 0.022194229066371918 35.88028096519969 30.0 0.0 no 13726 chrXV_800544 34167 essential YOR249C 168 - TTACTATTATCCTTGAGCAG S|62|T S|62|N 0 0 0 0 0.20199053272371367 Q08683 0.4564267694950104 0.3468547463417053 43.51366321579133 35.0 0.0 no 13727 chrXV_800572 34168 essential YOR249C 140 - ATTCTAGTGAAGGTCTAGTA E|53|Q E|53|K 0 0 0 0 -0.7578630587962893 Q08683 0.14916808903217316 0.13635940849781036 43.11049271109397 35.0 0.0 no 13728 chrXV_800634r 34170 essential YOR249C 75 + GCTCACTGCTCACAAGATAA H|27|D H|27|Y A|26|G A|26|V 0 0 0 0 -1.4692288491414331 Q08683 0.04977227374911308 1.0 0.21825125813484192 0.5880440473556519 46.4468385611703 45.0 0.0 no 13729 chrXV_801303 34171 essential YOR250C 985 - GCCGTAAAAGTACTCTCTTA G|335|R G|335|S G|335|A G|335|D CLP1 CLeavage/Polyadenylation factor Ia subunit 445.0 0 0 0 0 0.12957094267987154 Q08685 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 9.61485195159912 8.33149242401123 5.160470008850098 12.845345497131348 44.95920099122668 40.0 0.0 no 13730 chrXV_801304r 34172 essential YOR250C 981 + TCCATAAGAGAGTACTTTTA silent|TCC>TCG|S|328 silent|TCC>TCT|S|328 S|328|C S|328|F CLP1 CLeavage/Polyadenylation factor Ia subunit 445.0 0 0 0 0 -0.15605007771266824 Q08685 0.945252001285553 0.9294660091400146 0.1692124307155609 0.10696615278720856 2.417998075485229 11.51152229309082 40.222311063786265 30.0 0.0 no 13731 chrXV_801318 34173 essential YOR250C 970 - TCTTATGGATGTCCTCTGCA R|330|T R|330|K CLP1 CLeavage/Polyadenylation factor Ia subunit 445.0 0 0 0 0 0.19228844991021155 Q08685 0.932735025882721 0.955805003643036 0.0134977251291275 0.3046584725379944 0.3648400008678436 0.22346000373363492 52.73409034536365 45.0 0.0 no 13732 chrXV_801443r 34175 essential YOR250C 842 + TTCTGAAACGGATCCTCTTT S|282|C S|282|F CLP1 CLeavage/Polyadenylation factor Ia subunit 445.0 0 0 0 0 0.2970725868124615 Q08685 0.945252001285553 0.9294660091400146 0.030412150546908382 0.03673085942864418 0.6877999901771545 -0.08748000115156174 45.654965685475084 40.0 0.0 no 13733 chrXV_801533r 34177 essential YOR250C 752 + TACGCCATCAATATCACAAC T|252|R T|252|M P|253|A P|253|S CLP1 CLeavage/Polyadenylation factor Ia subunit 445.0 0 0 0 0 -0.4887374381672697 Q08685 0.9476869702339172 0.9502379894256592 0.9562489986419678 0.9498909711837769 0.0057578072883188725 0.003249800531193614 0.0 0.0 5.5451998710632315 0.2645600140094757 2.530895948410034 2.307346105575561 42.53219530565349 40.0 0.0 no 13734 chrXV_801689r 34181 essential YOR250C 596 + ACTACATAATAAGCAGCCAA L|200|V silent|CTA>TTA|L|200 H|201|D H|201|Y CLP1 CLeavage/Polyadenylation factor Ia subunit 445.0 0 0 0 0 0.05003209844131668 Q08685 0.9512209892272948 0.9473130106925964 0.9489949941635132 0.0553661547601223 0.0 0.0 0.4668599963188171 0.7743200063705444 0.44332000613212585 0.7779800295829773 0.17885999381542206 0.04320000112056732 41.15923539267709 35.0 0.0 no 13735 chrXV_801696 34182 essential YOR250C 592 - CTGCTTATTATGTAGTAGTG K|203|N silent|AAG>AAA|K|203 CLP1 CLeavage/Polyadenylation factor Ia subunit 445.0 0 0 0 0 -1.3234131802569904 Q08685 0.9355990290641784 0.0 0.2155800014734268 0.5258200168609619 42.296084860909616 35.0 0.0 no 13736 chrXV_801885r 34187 essential YOR250C 400 + CCGGGAAGACTTCCCTATCG silent|ACC>ACG|T|134 silent|ACC>ACT|T|134 CLP1 CLeavage/Polyadenylation factor Ia subunit 445.0 0 0 0 0 -0.9364402348707552 Q08685 53.73626214763408 60.0 0.0 no 13737 chrXV_801916 34189 essential YOR250C 372 - CCACCAACAATCACCACTCG G|130|A G|130|D G|131|R G|131|S CLP1 CLeavage/Polyadenylation factor Ia subunit 445.0 0 0 0 0 -1.4611803871425662 Q08685 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.0 0.0 0.4942212700843811 0.7444940805435181 4.080480098724365 15.205241203308105 -1.3082400560379028 -0.16816000640392306 50.285434418329935 55.00000000000001 0.0 no 13738 chrXV_801940r 34191 essential YOR250C 345 + ATACGAATGTCTAACTTTGA R|117|G R|117|* CLP1 CLeavage/Polyadenylation factor Ia subunit 445.0 0 0 0 0 0.5889881119047391 Q08685 0.8994590044021606 0.0 3.4552919864654537 37.5997652451278 30.0 0.0 no 13739 chrXV_802113 34193 essential YOR250C 175 - CTCATCATCTACTGCCAACT E|65|Q E|65|K D|64|H D|64|N CLP1 CLeavage/Polyadenylation factor Ia subunit 445.0 0 0 0 0 0.29292292737142817 Q08685 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.1503954827785492 0.03726209327578545 0.230443075299263 0.14574137330055234 -0.1052199974656105 -0.6237999796867371 -0.034839998930692666 -0.5415599942207336 49.71432339464098 45.0 0.0 no 13740 chrXV_802138r 34194 essential YOR250C 147 + TCGGGCATAGTTGAGATATT S|50|W S|50|L silent|GGC>GGG|G|51 silent|GGC>GGT|G|51 CLP1 CLeavage/Polyadenylation factor Ia subunit 445.0 0 0 0 0 -0.12554787675907836 Q08685 0.9288619756698608 0.9298099875450134 0.020172618329524997 0.2476538121700287 0.3993400037288666 -0.4503200054168701 45.6846937297509 40.0 0.0 no 13741 chrXV_802217r 34197 essential YOR250C 68 + GCACAAGTTGGTTATTCCCA H|24|Q silent|CAC>CAT|H|24 H|24|D H|24|Y CLP1 CLeavage/Polyadenylation factor Ia subunit 445.0 0 0 0 0 -0.20259394735177527 Q08685 0.9588389992713928 0.9473130106925964 0.9489949941635132 0.17363201081752774 0.2643688917160034 0.05653570219874383 -0.06840000301599503 1.6171000003814695 -1.87253999710083 52.193528312751475 45.0 0.0 no 13742 chrXV_802216r 34198 essential YOR250C 69 + CACAAGTTGGTTATTCCCAA H|24|Q silent|CAC>CAT|H|24 CLP1 CLeavage/Polyadenylation factor Ia subunit 445.0 0 0 0 0 -0.15318942548416234 Q08685 0.9588389992713928 0.17363201081752774 -0.06840000301599503 46.89292682238437 40.0 0.0 no 13743 chrXV_805655r 34201 essential YOR254C 1346 + ATACATTTCTTTGAAAGTAC Y|450|* silent|TAC>TAT|Y|450 SEC63 SECretory 663.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.07690529038467753 P14906 34.84398804205944 25.0 0.0 no 13744 chrXV_805800 34204 essential YOR254C 1204 - TCCAAGAACCTCACCAATCT G|408|R G|408|R G|408|A G|408|E SEC63 SECretory 663.0 0 1 0 0 -0.11901561670373666 P14906 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.0 0.0 0.0 0.0 48.56894713094471 45.0 0.0 no 13745 chrXV_805889 34210 essential YOR254C 1115 - TATCTACGTTCGGCAATTGA D|378|H D|378|N V|377|L V|377|I SEC63 SECretory 663.0 0 0 0 0 0.7597834089629858 P14906 0.9486550092697144 0.956179976463318 0.9539830088615416 0.9574310183525084 0.0141067486256361 0.21367497742176056 0.0 0.0 44.88369552185543 40.0 0.0 no 13746 chrXV_805940r 34211 essential YOR254C 1061 + TACTTTCAAGTGTATTGTTC T|355|S T|355|I F|356|L silent|TTC>TTT|F|356 SEC63 SECretory 663.0 0 0 0 0 1.5049806466148692 P14906 0.9491789937019348 0.9472420215606691 0.9387490153312684 0.3601788580417633 0.4922747313976288 0.6576005220413208 40.44994963164351 30.0 0.0 no 13747 chrXV_806012r 34212 essential YOR254C 989 + CTCTTTGTTACACGGTTTAT S|331|C S|331|F SEC63 SECretory 663.0 0 0 0 0 1.4197873848827762 P14906 0.945252001285553 0.9294660091400146 0.16923613846302032 0.6176177263259888 44.92757785826165 35.0 0.0 no 13748 chrXV_806175r 34214 essential YOR254C 826 + CCACAGATTTGATCTTACAC T|277|R T|277|I silent|ACC>ACG|T|276 silent|ACC>ACT|T|276 SEC63 SECretory 663.0 0 0 0 0 0.430022417192721 P14906 0.9476869702339172 0.9472420215606691 0.3203091621398926 0.5277925729751587 43.84826985584692 40.0 0.0 no 13749 chrXV_806266r 34215 essential YOR254C 735 + ACACAATCGTATACTAAGAA Q|247|E Q|247|* T|246|R T|246|I SEC63 SECretory 663.0 0 0 0 0 0.2197718198335553 P14906 0.9590039849281312 0.9476869702339172 0.9472420215606691 0.21725647151470184 0.03718319535255432 0.07771988213062286 35.493852109238965 30.0 0.0 no 13750 chrXV_806267r 34216 essential YOR254C 734 + AACACAATCGTATACTAAGA T|246|R T|246|I Q|247|E Q|247|* SEC63 SECretory 663.0 0 0 0 0 0.3178343286127823 P14906 0.9476869702339172 0.9472420215606691 0.9590039849281312 0.03718319535255432 0.07771988213062286 0.21725647151470184 35.493852109238894 30.0 0.0 no 13751 chrXV_806341 34217 essential YOR254C 663 - ACATAACAAACCACTAATAA V|228|L V|228|I C|226|S C|226|Y SEC63 SECretory 663.0 0 0 0 0 1.0896593484764452 P14906 0.9539830088615416 0.9574310183525084 0.9421560168266296 0.9290120005607604 0.5058678388595581 0.9277876615524292 0.4187743365764618 1.0 33.112463123829734 25.0 0.0 no 13752 chrXV_806437r 34218 essential YOR254C 564 + AGGCAAAACTATTTGAAATA Q|190|E Q|190|* SEC63 SECretory 663.0 0 0 0 0 -1.2072868409062247 P14906 0.9590039849281312 1.0 33.147374757806396 25.0 0.0 no 13753 chrXV_806456 34219 essential YOR254C 548 - GCCTAACCAATTCGTCAGTA R|189|T R|189|K R|189|S silent|AGG>AGA|R|189 SEC63 SECretory 663.0 0 0 0 0 0.3607950989052742 P14906 0.932735025882721 0.955805003643036 0.9087679982185364 0.02338739670813084 0.6967481970787048 0.018488867208361626 49.68477523697168 45.0 0.0 no 13754 chrXV_806457 34220 essential YOR254C 547 - CCTAACCAATTCGTCAGTAA R|189|T R|189|K V|188|L V|188|I SEC63 SECretory 663.0 0 0 0 0 0.08766280791340486 P14906 0.932735025882721 0.955805003643036 0.9539830088615416 0.9574310183525084 0.02338739670813084 0.6967481970787048 0.09661940485239028 0.13992971181869507 44.68809116514206 40.0 0.0 no 13755 chrXV_806489r 34222 essential YOR254C 512 + AACTTATGTTCAGATTACGA T|172|S T|172|I SEC63 SECretory 663.0 0 0 0 0 0.0003455826765300096 P14906 0.9491789937019348 0.9472420215606691 0.8060076236724854 0.20051442086696625 38.70634500932499 30.0 0.0 no 13756 chrXV_806515 34223 essential YOR254C 489 - TCCATCACACTTTTCTCATC M|169|I M|169|I E|170|Q E|170|K SEC63 SECretory 663.0 0 0 0 0 0.2389843377927803 P14906 0.9553959965705872 0.9553959965705872 0.956179976463318 0.9475290179252625 0.40700533986091614 0.40700533986091614 0.0 0.0 48.80624367712471 40.0 0.0 no 13757 chrXV_806516r 34224 essential YOR254C 485 + ACCTGATGAGAAAAGTGTGA P|163|R P|163|L P|163|A P|163|S SEC63 SECretory 663.0 0 0 0 0 0.014373097914239132 P14906 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.06579340249300003 0.046573523432016366 0.17446520924568176 0.10942243039608003 40.91238832783 40.0 0.0 no 13758 chrXV_806542 34225 essential YOR254C 462 - AGGCCCTTTGCTAATTTATC G|160|A G|160|D G|160|R G|160|S SEC63 SECretory 663.0 0 0 0 0 1.0188264630334751 P14906 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.20001834630966187 0.989426612854004 0.13635188341140747 0.5908163189888 49.72052168565659 40.0 0.0 no 13759 chrXV_806522 34226 essential YOR254C 482 - CACTTTTCTCATCAGGTGTT S|167|T S|167|N SEC63 SECretory 663.0 0 0 0 0 0.5158595187260681 P14906 0.9512869715690612 0.9536849856376648 0.9933049082756042 0.5206837058067322 49.17514309971466 40.0 0.0 no 13760 chrXV_806546r 34227 essential YOR254C 455 + TCATCCAGATAAATTAGCAA H|153|D H|153|Y P|154|A P|154|S SEC63 SECretory 663.0 0 0 0 0 0.015105616004904787 P14906 0.9473130106925964 0.9489949941635132 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 38.82029080681429 30.0 0.0 no 13761 chrXV_806962r 34231 essential YOR254C 39 + TGGCCGTCCTTCATTTTAAC P|15|A P|15|S P|15|R P|15|L SEC63 SECretory 663.0 0 0 0 0 1.1790371562911788 P14906 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.0 0.0 0.0 0.0 51.05238820954104 45.0 0.0 no 13762 chrXV_808871 34232 essential YOR256C 1793 - TATCCTCAGATGTTTCAGTT D|604|H D|604|N E|603|D silent|GAG>GAA|E|603 TRE2 Transferrrin REceptor like 809.0 0 0 0 0 0.3535705816481593 Q08693 0.0 0.0 0.5906312465667725 47.30426114264486 35.0 0.0 no 13763 chrXV_809083 34233 essential YOR256C 1581 - TTCTCATATTTTTCGGCAAA E|533|D silent|GAG>GAA|E|533 E|533|Q E|533|K TRE2 Transferrrin REceptor like 809.0 0 0 0 0 0.4005217502292148 Q08693 41.67972413429635 30.0 0.0 no 13764 chrXV_809163r 34234 essential YOR256C 1498 + CTTCGGAGCTGGTTGAGCAA S|501|W S|501|L TRE2 Transferrrin REceptor like 809.0 0 0 0 0 -0.4253868542344528 Q08693 0.0017526529263705015 0.009787749499082564 52.561290801558705 55.00000000000001 0.0 no 13765 chrXV_809209r 34235 essential YOR256C 1452 + ATCTATTTCATCTCATTCGG I|485|M silent|ATC>ATT|I|485 TRE2 Transferrrin REceptor like 809.0 0 0 0 0 0.2276349510138753 Q08693 0.006541112903505564 44.23558598510937 35.0 0.0 no 13766 chrXV_809392 34236 essential YOR256C 1272 - TCAATTTTACCAACAATATT E|431|Q E|431|K TRE2 Transferrrin REceptor like 809.0 0 0 0 0 0.7286835716785507 Q08693 0.10615124553442 0.017923302948474884 35.015475638727935 20.0 0.0 no 13767 chrXV_809524r 34237 essential YOR256C 1137 + CTACTATCGCGTTTATCTTC L|381|V silent|CTA>TTA|L|381 TRE2 Transferrrin REceptor like 809.0 0 0 0 0 0.8759784719324769 Q08693 0.0961141362786293 45.855619375431225 40.0 0.0 no 13768 chrXV_809544 34238 essential YOR256C 1120 - TAGCTCTTTTCCTTGTCTCG E|379|D silent|GAG>GAA|E|379 E|379|Q E|379|K TRE2 Transferrrin REceptor like 809.0 0 0 0 0 0.6067437309098084 Q08693 0.5041142106056213 0.5430268049240112 1.0 52.79615819787358 45.0 0.0 no 13769 chrXV_808915 34240 essential YOR256C 1749 - TCAGAAGATATTACAGATAC D|590|H D|590|N TRE2 Transferrrin REceptor like 809.0 0 0 0 0 1.1461408284499823 Q08693 0.033522449433803565 0.2755952477455139 34.47814199253605 30.0 0.0 no 13770 chrXV_809651 34241 essential YOR256C 1013 - ATGCATCACCAGTCGAATAT A|344|P A|344|T D|343|H D|343|N TRE2 Transferrrin REceptor like 809.0 0 0 0 0 0.05337646158174554 Q08693 0.3436380624771118 0.313427597284317 0.0 0.0 45.951709211020784 40.0 0.0 no 13771 chrXV_809653 34243 essential YOR256C 1011 - GCATCACCAGTCGAATATTG A|344|P A|344|T D|343|H D|343|N TRE2 Transferrrin REceptor like 809.0 0 0 0 0 -0.7646574310843097 Q08693 0.3436380624771118 0.313427597284317 0.0 0.0 46.21490134632239 45.0 0.0 no 13772 chrXV_809716r 34244 essential YOR256C 945 + ATCTTCATATCTGAGCCATA I|316|M silent|ATC>ATT|I|316 F|317|L silent|TTC>TTT|F|317 TRE2 Transferrrin REceptor like 809.0 0 0 0 0 1.052424165956136 Q08693 0.03615744039416313 0.0 46.419744795770036 35.0 0.0 no 13773 chrXV_809752r 34245 essential YOR256C 909 + GTACTAATTGCTGAGAAATT L|305|V silent|CTA>TTA|L|305 TRE2 Transferrrin REceptor like 809.0 0 0 0 0 0.29283194559525466 Q08693 0.1770954728126526 37.02093452990664 30.0 0.0 no 13774 chrXV_809875r 34247 essential YOR256C 786 + AGCTTGATTTATGGAGGCAA S|263|R silent|AGC>AGT|S|263 TRE2 Transferrrin REceptor like 809.0 0 0 0 0 -1.3621602867436085 Q08693 0.2807581126689911 45.69625420079206 40.0 0.0 no 13775 chrXV_809883 34248 essential YOR256C 781 - TCCATAAATCAAGCTCACTT G|267|R G|267|R G|267|A G|267|E TRE2 Transferrrin REceptor like 809.0 0 0 0 0 -0.09862916632522699 Q08693 0.040912892669439316 0.040912892669439316 1.0 0.05321340262889862 42.94679708691621 35.0 0.0 no 13776 chrXV_809884r 34249 essential YOR256C 777 + TCCAAAGTGAGCTTGATTTA silent|TCC>TCG|S|260 silent|TCC>TCT|S|260 S|260|C S|260|F TRE2 Transferrrin REceptor like 809.0 0 0 0 0 -0.4628698510488531 Q08693 0.081943579018116 0.17036686837673187 43.07973238122111 35.0 0.0 no 13777 chrXV_809913r 34250 essential YOR256C 748 + TCAATCCGTTGAGTTCTAAC F|250|L silent|TTC>TTT|F|250 P|252|A P|252|S TRE2 Transferrrin REceptor like 809.0 0 0 0 0 -4.386012150399308 Q08693 0.024032542482018467 0.05684386566281319 0.14156676828861234 44.068238188392 40.0 0.0 yes 13778 chrXV_809914r 34251 essential YOR256C 747 + TTCAATCCGTTGAGTTCTAA F|250|L silent|TTC>TTT|F|250 P|252|A P|252|S TRE2 Transferrrin REceptor like 809.0 0 0 0 0 1.1068051548526607 Q08693 0.024032542482018467 0.05684386566281319 0.14156676828861234 43.88211535850331 35.0 0.0 no 13779 chrXV_810004r 34252 essential YOR256C 657 + TCAGTTTATTCTAATTATCC S|220|* S|220|L TRE2 Transferrrin REceptor like 809.0 0 0 0 0 -0.11343014913603955 Q08693 0.3029283583164215 39.321077220674965 25.0 0.0 no 13780 chrXV_810074r 34253 essential YOR256C 587 + AGCTATTTATCGATACATTC A|197|G A|197|V TRE2 Transferrrin REceptor like 809.0 0 0 0 0 0.7122495228129551 Q08693 0.05021340399980545 0.06374263018369675 39.94803473763329 30.0 0.0 no 13781 chrXV_810093 34254 essential YOR256C 571 - AGCTGCATCACCCTTCGTTC A|197|P A|197|T A|196|P A|196|T TRE2 Transferrrin REceptor like 809.0 0 0 0 0 0.06403403558910252 Q08693 0.02777540497481823 0.03279680386185646 0.2043261826038361 0.406730592250824 58.506191924782904 55.00000000000001 0.0 no 13782 chrXV_810256r 34259 essential YOR256C 405 + GCATATTATGTCTTGTCAAG A|136|G A|136|V TRE2 Transferrrin REceptor like 809.0 0 0 0 0 0.8011966373227333 Q08693 0.02748083509504795 1.0 42.13223396199828 35.0 0.0 no 13783 chrXV_810493 34262 essential YOR256C 171 - TCTATATCAAATTCATAAGA E|64|Q E|64|K TRE2 Transferrrin REceptor like 809.0 0 0 0 0 -0.15784069292417244 Q08693 0.532110333442688 0.8307622671127319 32.20543512876134 20.0 0.0 no 13784 chrXV_811040 34266 essential YOR257W 32 + TCCACTTAATAGCGAGTTAT P|12|R P|12|L P|12|A P|12|S CDC31 Cell Division Cycle 161.0 0 1 0 0 -2.3757564327880014 P06704 0.5574605464935303 0.291921466588974 0.8961769342422485 0.7626854777336121 1.854259967803955 1.8010400533676147 1.6390000581741333 1.94376003742218 43.71717286945579 35.0 1.0 yes 13785 chrXV_811041r 34268 essential YOR257W 36 - TCCAATAACTCGCTATTAAG L|18|F silent|TTG>TTA|L|18 E|19|Q E|19|K CDC31 Cell Division Cycle 161.0 0 0 0 0 -1.1102292884879468 P06704 0.00788668356835842 0.23974741995334625 0.28718000650405884 -0.15109999477863312 0.8556200265884399 0.9511600136756896 0.15411999821662906 39.79108806373881 35.0 1.0 no 13786 chrXV_811160r 34271 essential YOR257W 155 - TCTTGGGTAGCTCAAATCCC K|58|N silent|AAG>AAA|K|58 CDC31 Cell Division Cycle 161.0 0 0 0 0 -1.072544265615767 P06704 0.05895870178937913 0.9020799994468688 2.7460401058197017 52.576006770719395 50.0 1.0 no 13787 chrXV_812952r 34273 essential YOR259C 734 + CTCTCCAGCGTCTGGTATTG S|246|C S|246|F P|247|A P|247|S RPT4 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 437.0 0 0 0 0 -0.7375325432625772 P53549 0.0710071548819542 0.0034888691734522577 0.18913082778453827 0.3729289472103119 -0.15379999577999115 -0.4600000083446503 55.37116028370128 55.00000000000001 0.0 no 13788 chrXV_812960r 34274 essential YOR259C 726 + TTCATTTTCTCTCCAGCGTC F|243|L silent|TTC>TTT|F|243 RPT4 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 437.0 0 0 0 0 0.7226673002874135 P53549 0.004595791921019554 53.39900651117921 45.0 0.0 no 13789 chrXV_813081r 34281 essential YOR259C 605 + GAACCCAGAAATTTTCCAGA N|203|K silent|AAC>AAT|N|203 P|204|A P|204|S RPT4 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 437.0 0 0 0 0 -0.09612826332904573 P53549 0.02569713070988655 0.0 0.0 44.75912059458915 40.0 0.0 no 13790 chrXV_813281r 34284 essential YOR259C 405 + GATCGCTCTAAATTAAAGAA R|137|G R|137|C silent|CGC>CGG|R|137 silent|CGC>CGT|R|137 RPT4 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 437.0 0 0 0 0 0.3615162380695297 P53549 0.34804078936576843 0.1823272407054901 34.772109264868156 30.0 0.0 no 13791 chrXV_813315 34286 essential YOR259C 374 - TAACTCCGACAATATAACGT V|131|L V|131|I G|130|A G|130|E RPT4 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 437.0 0 0 0 0 -0.9172146148597808 P53549 0.942442774772644 0.641922116279602 0.17548878490924835 0.21354399621486664 39.22876411236939 35.0 0.0 no 13792 chrXV_813320r 34287 essential YOR259C 366 + TCGGGCCCACGTTATATTGT S|123|W S|123|L silent|GGC>GGG|G|124 silent|GGC>GGT|G|124 RPT4 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 437.0 0 0 0 0 -0.01466121432484971 P53549 0.0133693628013134 0.18599504232406616 54.507510753387976 50.0 0.0 no 13793 chrXV_813602 34289 essential YOR259C 87 - TCCGTTTCCTGTGGTTGTTC silent|ACG>ACC|T|35 silent|ACG>ACA|T|35 E|36|Q E|36|K RPT4 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 437.0 0 0 0 0 -1.8705372134927667 P53549 0.5483635067939758 0.8767738938331604 57.298034538112965 50.0 0.0 no 13794 chrXV_813669r 34292 essential YOR259C 17 + CCCTTTATTAGCAGGATTGG P|7|R P|7|L P|7|A P|7|S RPT4 Regulatory Particle Triple-A protein, or Regulatory Particle Triphosphatase 437.0 0 0 0 0 -3.6585084603466695 P53549 49.73106051908922 45.0 0.0 yes 13795 chrXV_814007 34295 essential YOR260W 23 + TTGCGGTAAAGGTTCCAATT C|9|W silent|TGC>TGT|C|9 GCD1 General Control Derepressed 578.0 0 0 0 0 -0.023055348312739917 P09032 0.9663929939270021 0.0 45.73901435042911 40.0 1.0 no 13796 chrXV_813996 34296 essential YOR260W 12 + GCTTTTGTCTTTTGCGGTAA A|5|G A|5|V GCD1 General Control Derepressed 578.0 0 0 0 0 0.6682901319749254 P09032 0.9919250011444092 0.991150975227356 0.03282955288887024 0.16252459585666654 49.44719443821861 40.0 1.0 no 13797 chrXV_814058r 34298 essential YOR260W 77 - TACTGTCTTTGTTCTGCGTT S|32|T S|32|N D|31|H D|31|N GCD1 General Control Derepressed 578.0 0 0 0 0 0.4896646149385399 P09032 0.9219859838485718 0.9260370135307312 0.9899479746818542 1.0004899501800537 50.47000816643544 40.0 1.0 no 13798 chrXV_814053r 34299 essential YOR260W 72 - TCTTTGTTCTGCGTTTGGAA D|31|H D|31|N GCD1 General Control Derepressed 578.0 0 0 0 0 -0.8435540763505738 P09032 0.9899479746818542 1.0004899501800537 48.23939536477753 40.0 1.0 no 13799 chrXV_814160 34301 essential YOR260W 176 + ACATTCAACGCGCTTGCCCA H|60|D H|60|Y S|61|* S|61|L GCD1 General Control Derepressed 578.0 0 0 0 0 0.4661592764898125 P09032 0.9107649922370912 0.9109159708023072 0.8951669931411743 0.2045160681009293 0.13230207562446594 0.2635369300842285 55.70397670361877 55.00000000000001 1.0 no 13800 chrXV_814176 34302 essential YOR260W 192 + CCCAAGGCTCTTTTGCCCAT silent|CCC>CCG|P|65 silent|CCC>CCT|P|65 P|65|R P|65|L GCD1 General Control Derepressed 578.0 0 0 0 0 0.4739414774732514 P09032 0.9074479937553406 0.9137349724769592 0.009739360772073269 0.00996487308293581 60.05584023320404 55.00000000000001 1.0 no 13801 chrXV_814191r 34305 essential YOR260W 210 - ATCATAGGTCTATTACCGAT M|76|I M|76|I GCD1 General Control Derepressed 578.0 0 0 0 0 -0.21711806659382296 P09032 0.999705970287323 0.999705970287323 0.07644609361886978 0.07644609361886978 44.62440600936179 35.0 1.0 no 13802 chrXV_814192r 34306 essential YOR260W 211 - AATCATAGGTCTATTACCGA M|76|I M|76|I GCD1 General Control Derepressed 578.0 0 0 0 0 0.282464467554497 P09032 0.999705970287323 0.999705970287323 0.07644609361886978 0.07644609361886978 43.134299638081245 35.0 1.0 no 13803 chrXV_814206r 34308 essential YOR260W 225 - TCCAAGACGTATTCAATCAT L|81|F silent|TTG>TTA|L|81 D|82|H D|82|N GCD1 General Control Derepressed 578.0 0 0 0 0 -1.9141694222089147 P09032 1.0031700134277344 0.9597970247268676 0.9710310101509094 0.0 0.015203998424112797 0.04938163235783577 42.19134725968763 35.0 1.0 no 13804 chrXV_814322r 34310 essential YOR260W 341 - GTTCAAATTGTTGCTTTCTT E|120|Q E|120|K GCD1 General Control Derepressed 578.0 0 0 0 0 0.8992167831628698 P09032 0.9202449917793274 0.9081959724426271 0.14257915318012238 0.5524805784225464 43.28700733384756 30.0 1.0 no 13805 chrXV_814334 34311 essential YOR260W 350 + ACAATTTGAACTAATATACA Q|118|E Q|118|* GCD1 General Control Derepressed 578.0 0 0 0 0 -0.13119064349452753 P09032 0.9365779757499696 0.9134185910224916 31.54344404932641 20.0 1.0 no 13806 chrXV_814416r 34314 essential YOR260W 435 - CCTGTAGAATTTGCCTTCGA G|152|R G|152|S GCD1 General Control Derepressed 578.0 0 0 0 0 0.3451641719432443 P09032 0.904865026473999 0.9219319820404052 0.02945586293935776 0.2236416041851044 49.90370244622034 45.0 1.0 no 13807 chrXV_814455 34316 essential YOR260W 471 + GAGCTTTTGCCTAGAATCAA L|159|V L|159|F GCD1 General Control Derepressed 578.0 0 0 0 0 1.5954260286764852 P09032 0.9148989915847778 0.9236630201339722 0.14471523463726044 0.10936569422483444 46.01262554272858 40.0 1.0 no 13808 chrXV_814464r 34317 essential YOR260W 483 - ACAAAATCGCCATTGATTCT V|168|L V|168|I GCD1 General Control Derepressed 578.0 0 0 0 0 -1.193499126672207 P09032 0.9175459742546082 0.9252150058746338 0.05580925568938255 0.5418863296508789 42.194878428129016 35.0 1.0 no 13809 chrXV_814881 34320 essential YOR260W 897 + TCATTCAAAGATCCATTTAC S|300|* S|300|L F|301|L silent|TTC>TTT|F|301 GCD1 General Control Derepressed 578.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.18623685931964126 P09032 0.8951669931411743 0.9066330194473268 0.3451643288135529 0.6333026289939879 38.935516594150435 30.0 1.0 no 13810 chrXV_814922r 34321 essential YOR260W 941 - CATCATCATCAGTAGTAGGA D|320|H D|320|N D|319|H D|319|N GCD1 General Control Derepressed 578.0 0 1 0 0 -0.3646411213918987 P09032 0.9899479746818542 1.0004899501800537 0.9899479746818542 1.0004899501800537 0.14870555698871613 0.4559730589389801 0.1361749917268753 0.4497668743133545 45.205322695703394 40.0 1.0 no 13811 chrXV_814926r 34322 essential YOR260W 945 - TCTTCATCATCATCAGTAGT D|322|H D|322|N E|321|Q E|321|K GCD1 General Control Derepressed 578.0 0 0 0 0 -0.18292815696103265 P09032 0.9899479746818542 1.0004899501800537 1.0004899501800537 0.9891330003738404 0.19672459363937375 0.5089681148529053 0.6487706899642944 0.9012793898582458 46.291105155358316 35.0 1.0 no 13812 chrXV_816201 34326 essential YOR261C 711 - TCATCAGGTGTTCCCAGATT D|244|H D|244|N D|243|H D|243|N RPN8 Regulatory Particle Non-ATPase 338.0 0 0 0 0 0.13963436370005627 Q08723 0.02195869944989681 0.05519947037100792 53.629166001663926 45.0 0.0 no 13813 chrXV_816213r 34327 essential YOR261C 696 + TTCAACCTTTTACCAAATCT F|233|L silent|TTC>TTT|F|233 N|234|K silent|AAC>AAT|N|234 RPN8 Regulatory Particle Non-ATPase 338.0 0 0 0 0 -0.18808420695900324 Q08723 0.21912245452404025 0.00760722393169999 0.6608200073242188 -0.3248800039291382 42.1227635760913 30.0 0.0 no 13814 chrXV_816253r 34329 essential YOR261C 656 + ACCGATAAACCACACTATAT P|220|R P|220|L P|220|A P|220|S RPN8 Regulatory Particle Non-ATPase 338.0 0 1 0 0 -0.2885576638000126 Q08723 0.005375218577682972 0.0034628503490239377 0.025834959000349045 0.06058880314230919 41.301932979702364 35.0 0.0 no 13815 chrXV_816338 34330 essential YOR261C 574 - TTTCAAAGATTTTAATTGGT L|197|F silent|TTG>TTA|L|197 RPN8 Regulatory Particle Non-ATPase 338.0 0 1 0 0 -0.8089947048084125 Q08723 0.007991647347807884 -0.1146399974822998 34.3467516467735 20.0 0.0 no 13816 chrXV_816365r 34331 essential YOR261C 544 + CAGCAGGTGGCTTATCTATC A|183|G A|183|V RPN8 Regulatory Particle Non-ATPase 338.0 0 0 0 0 0.5040682493347111 Q08723 0.0009398989495821297 1.0 51.959334957737504 50.0 0.0 no 13817 chrXV_816445r 34335 essential YOR261C 464 + TCATTTGCCTTGTACTATTG H|156|D H|156|Y RPN8 Regulatory Particle Non-ATPase 338.0 0 0 0 0 0.7922694225805798 Q08723 0.022922039031982425 0.006898486986756325 0.5856559872627258 -0.9613959789276124 -0.20532000064849854 -0.344760000705719 1.937399983406067 -0.8104000091552734 45.57289042984604 35.0 0.0 no 13818 chrXV_816438 34336 essential YOR261C 474 - TCTTCGGCCTCAATAGTACA E|165|Q E|165|K E|164|Q E|164|K RPN8 Regulatory Particle Non-ATPase 338.0 0 0 0 0 -1.2652206999479323 Q08723 0.017418527975678444 0.013368206098675728 0.2840476334095001 0.28357502818107605 -0.049079999327659614 0.13408799469470978 1.5521939992904663 2.199779987335205 0.5130599737167358 0.3682999908924103 2.583440065383911 2.3036599159240723 50.24875862889979 45.0 0.0 no 13819 chrXV_816513 34338 essential YOR261C 399 - ATCGCGACATATGCATCTGT silent|GCG>GCC|A|139 silent|GCG>GCA|A|139 A|139|P A|139|T RPN8 Regulatory Particle Non-ATPase 338.0 0 0 0 1 -0.3208035744611903 Q08723 0.02077207714319229 0.15210267901420593 -2.012115955352783 1.1285059452056885 6.620359897613525 2.7185800075531006 48.86810737059693 45.0 0.0 no 13820 chrXV_816656 34341 essential YOR261C 256 - CCATCCAATGAGTTTTTCCT W|92|S W|92|* G|91|A G|91|E RPN8 Regulatory Particle Non-ATPase 338.0 0 0 0 0 -6.5388503115009335 Q08723 0.0 0.0 0.0 6.056801795959473 8.91555404663086 31.460756301879886 50.37649047420877 40.0 0.0 yes 13821 chrXV_816703 34343 essential YOR261C 209 - TCATGTTTTCAATATAATTA M|76|I M|76|I RPN8 Regulatory Particle Non-ATPase 338.0 0 0 0 0 0.5316395080731684 Q08723 0.0 0.0 0.4608379900455475 0.4608379900455475 -0.12092000246047975 -0.12092000246047975 32.664805282850466 15.0 0.0 no 13822 chrXV_816752 34344 essential YOR261C 160 - CTCATCTTCTTCAAACGGTA E|60|Q E|60|K D|59|H D|59|N RPN8 Regulatory Particle Non-ATPase 338.0 0 0 0 0 0.6556057827421241 Q08723 0.1278354972600937 0.2233540564775467 0.002152880886569619 0.005868465173989534 0.0661339983344078 0.32521799206733704 -0.06462600082159042 -0.02278600074350834 44.761635591058685 40.0 0.0 no 13823 chrXV_816874r 34346 essential YOR261C 35 + ACTAGTTTTGCTATCTGCTT L|13|V silent|CTA>TTA|L|13 RPN8 Regulatory Particle Non-ATPase 338.0 0 0 0 0 0.5621032837890588 Q08723 0.017733871936798096 0.4023459851741791 0.7106800079345703 48.030319951497184 35.0 0.0 no 13824 chrXV_816884 34347 essential YOR261C 28 - TAGCAAAACTAGTGGTGCAA L|15|F silent|TTG>TTA|L|15 RPN8 Regulatory Particle Non-ATPase 338.0 0 0 0 0 -2.3283552392322195 Q08723 0.0 0.4780539870262146 3.3476600646972656 41.88979163651584 40.0 0.0 yes 13825 chrXV_817296r 34348 essential YOR262W 7 - ACCAATAACAATCTGAGCGA G|9|R G|9|S G|9|A G|9|D GPN2 Gly-Pro-Asn (N) motif 347.0 0 0 0 0 -2.176208114190376 Q08726 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 41.92073641190342 40.0 1.0 yes 13826 chrXV_817422r 34350 essential YOR262W 133 - CACAGCGCATGGGTAAGGTA V|51|L V|51|M A|50|P A|50|T GPN2 Gly-Pro-Asn (N) motif 347.0 0 0 0 0 -0.8836321782528671 Q08726 0.9539830088615416 0.9587630033493042 0.9573720097541808 0.9523990154266356 1.0 0.1431739777326584 0.031034858897328373 0.3318775296211243 51.77431378115745 55.00000000000001 1.0 no 13827 chrXV_817432r 34351 essential YOR262W 143 - CACGAATATCCACAGCGCAT R|54|P R|54|H GPN2 Gly-Pro-Asn (N) motif 347.0 0 0 0 0 -0.6848929418571924 Q08726 0.9099509716033936 0.9570810198783876 0.05232669785618782 0.031590033322572715 48.68642469264871 50.0 1.0 no 13828 chrXV_817433r 34352 essential YOR262W 144 - TCACGAATATCCACAGCGCA R|54|P R|54|H D|55|H D|55|N GPN2 Gly-Pro-Asn (N) motif 347.0 0 0 0 0 0.973397435490517 Q08726 0.9099509716033936 0.9570810198783876 0.9486550092697144 0.956179976463318 0.05232669785618782 0.031590033322572715 0.02103508822619915 0.16636666655540466 49.67200245817895 50.0 1.0 no 13829 chrXV_817450 34353 essential YOR262W 158 + TCGTGATTTTATAACATTAG R|54|G R|54|C GPN2 Gly-Pro-Asn (N) motif 347.0 0 0 0 0 0.7546143039398542 Q08726 0.8994590044021606 0.8926740288734436 0.07278665900230408 0.010673659853637218 35.01482325092309 25.0 1.0 no 13830 chrXV_817484 34354 essential YOR262W 192 + GAGCAACAGTTAGGCCCTAA Q|66|E Q|66|* Q|67|E Q|67|* GPN2 Gly-Pro-Asn (N) motif 347.0 0 0 0 0 0.09338493351232058 Q08726 0.9590039849281312 0.9590039849281312 1.0 1.0 51.38991443305145 50.0 1.0 no 13831 chrXV_817487 34356 essential YOR262W 195 + CAACAGTTAGGCCCTAATGG Q|67|E Q|67|* GPN2 Gly-Pro-Asn (N) motif 347.0 0 0 0 0 -0.17324141765461734 Q08726 0.9590039849281312 1.0 48.79840082769391 50.0 1.0 no 13832 chrXV_817499r 34357 essential YOR262W 210 - GCATACATCAAACCTCCATT A|77|P A|77|T M|75|I M|75|I GPN2 Gly-Pro-Asn (N) motif 347.0 0 0 0 0 -1.6681368125027367 Q08726 0.9573720097541808 0.9523990154266356 0.9553959965705872 0.9553959965705872 0.01960219442844391 0.01571759581565857 0.14759866893291473 0.14759866893291473 47.00312921069275 40.0 1.0 no 13833 chrXV_817595 34358 essential YOR262W 303 + TATCTTGTATTCGACTGTCC L|103|V L|103|F GPN2 Gly-Pro-Asn (N) motif 347.0 0 0 0 0 -0.5358471735825944 Q08726 0.9512209892272948 0.9587849974632264 1.0 0.13679322600364685 47.10165480475683 40.0 1.0 no 13834 chrXV_817603 34359 essential YOR262W 311 + ATTCGACTGTCCGGGCCAAG F|105|L silent|TTC>TTT|F|105 D|106|E silent|GAC>GAT|D|106 GPN2 Gly-Pro-Asn (N) motif 347.0 0 0 0 0 0.14187851812067198 Q08726 0.9387490153312684 0.9532920122146606 0.3091069161891937 0.0 55.115229154053104 60.0 1.0 no 13835 chrXV_817879r 34363 essential YOR262W 590 - GCTCCAAATAATCCAGATCC E|203|Q E|203|K E|203|D silent|GAG>GAA|E|203 GPN2 Gly-Pro-Asn (N) motif 347.0 0 0 0 0 0.7083062298167269 Q08726 0.956179976463318 0.9475290179252625 0.94931298494339 0.6739731431007385 0.9477339386940002 0.5801271796226501 47.74137737616274 45.0 1.0 no 13836 chrXV_817996 34364 essential YOR262W 704 + ATCATTTGAGGTTTTGTCCG S|236|* S|236|L GPN2 Gly-Pro-Asn (N) motif 347.0 0 0 0 0 -0.08737980726358485 Q08726 0.9298099875450134 0.06636323034763336 47.66264474282138 40.0 1.0 no 13837 chrXV_832903r 34365 essential YOR272W 93 - CCATATCTCTTTAATGAGAT G|38|R G|38|R R|36|T R|36|K YTM1 460.0 0 1 0 0 -0.43446231069204144 Q12024 0.012174196541309357 0.012174196541309357 0.0 0.0 40.34152839285952 30.0 1.0 no 13838 chrXV_832904 34366 essential YOR272W 91 + CCATCTCATTAAAGAGATAT silent|CCC>CCG|P|31 silent|CCC>CCT|P|31 I|32|M silent|ATC>ATT|I|32 YTM1 460.0 0 0 0 1 0.2666522265183596 Q12024 0.02501988410949707 38.28180753956451 30.0 1.0 no 13839 chrXV_833058 34369 essential YOR272W 245 + GCTGAATGTAGAATATACCA L|83|V silent|CTG>TTG|L|83 YTM1 460.0 0 0 0 0 -0.004953853422399235 Q12024 0.022154511883854863 40.72137098613553 35.0 1.0 no 13840 chrXV_833089r 34370 essential YOR272W 279 - AAACTATTCAAATAGGATGG S|99|T S|99|N YTM1 460.0 0 0 0 0 -0.9187977744398316 Q12024 0.0 0.0 33.75462519102416 30.0 1.0 no 13841 chrXV_833191 34373 essential YOR272W 378 + GTTCGCACCTGGGATTTATC R|128|G R|128|C silent|CGC>CGG|R|128 silent|CGC>CGT|R|128 YTM1 460.0 0 0 0 0 -1.3301571456491823 Q12024 0.0 0.0 52.34498225335847 50.0 1.0 no 13842 chrXV_833224 34374 essential YOR272W 411 + AAGCAGTACAGTGGTCATTC Q|139|E Q|139|* YTM1 460.0 0 0 0 0 0.5445296724058055 Q12024 0.06376401335000992 47.85843499237433 45.0 1.0 no 13843 chrXV_833300 34375 essential YOR272W 487 + ACGACCGTACTTTGAGATTA N|163|K silent|AAC>AAT|N|163 D|164|E silent|GAC>GAT|D|164 YTM1 460.0 0 1 0 0 0.5218184256950716 Q12024 0.6414467692375183 0.0 44.57299769384815 40.0 1.0 no 13844 chrXV_833349 34376 essential YOR272W 536 + AACTTCACAACAACAGGCAC T|180|S T|180|I S|181|* S|181|L YTM1 460.0 0 0 0 0 0.6050356857966891 Q12024 0.938493311405182 0.2461400032043457 0.1088663935661316 42.7441307608247 45.0 1.0 no 13845 chrXV_833485 34378 essential YOR272W 672 + GCATCATACGACAATTCTAT A|225|G A|225|V S|226|* S|226|L YTM1 460.0 0 0 0 0 -1.900570005315747 Q12024 0.3557032942771912 0.016105452552437782 0.007282582577317953 41.658516895756925 35.0 1.0 no 13846 chrXV_833492 34379 essential YOR272W 679 + ACGACAATTCTATTGGGTTC Y|227|* silent|TAC>TAT|Y|227 D|228|E silent|GAC>GAT|D|228 YTM1 460.0 0 0 0 0 -0.3960736050572081 Q12024 0.0 43.676852330047204 40.0 1.0 no 13847 chrXV_833582 34380 essential YOR272W 769 + TATCCACTGCTGCTAGAAAA S|258|C S|258|F silent|TCC>TCG|S|258 silent|TCC>TCT|S|258 YTM1 460.0 0 1 0 0 0.001003005938755186 Q12024 0.018593933433294296 0.017766406759619713 44.180069466589934 40.0 1.0 no 13848 chrXV_833585r 34381 essential YOR272W 775 - TCTCCTTTTTCTAGCAGCAG R|264|S silent|AGG>AGA|R|264 R|265|T R|265|K YTM1 460.0 0 0 0 0 0.4335979125549062 Q12024 0.006958519574254751 0.012807478196918964 0.3037710785865784 52.79337133992436 45.0 1.0 no 13849 chrXV_833677r 34383 essential YOR272W 867 - TCGAAGATCACTTGCTCAAC D|296|H D|296|N YTM1 460.0 0 0 0 0 0.6607976327515703 Q12024 0.3784726858139038 0.7435437440872192 43.92500551282768 45.0 1.0 no 13850 chrXV_833768r 34384 essential YOR272W 958 - TCTTGTATCTATACATCTCG R|326|T R|326|K YTM1 460.0 0 0 0 0 -0.0023323478887024296 Q12024 0.010530298575758934 0.2964114248752594 42.62556060814393 35.0 1.0 no 13851 chrXV_842867r 34386 essential YOR278W 53 - CCAATTCATATTTATCAATG L|24|F silent|TTG>TTA|L|24 E|23|Q E|23|K HEM4 HEMe biosynthesis 275.0 0 0 0 0 0.11259192957690628 P06174 0.9587849974632264 0.956179976463318 0.9475290179252625 0.0799436941742897 0.3832037746906281 0.5577753782272339 -0.06960000097751617 36.033265887103774 25.0 1.0 no 13852 chrXV_842868r 34387 essential YOR278W 54 - TCCAATTCATATTTATCAAT L|24|F silent|TTG>TTA|L|24 E|25|Q E|25|K HEM4 HEMe biosynthesis 275.0 0 0 0 0 1.0191447044545905 P06174 0.9587849974632264 0.956179976463318 0.9475290179252625 0.0799436941742897 0.588165283203125 0.9312180280685424 -0.06960000097751617 36.78987319016488 20.0 1.0 no 13853 chrXV_842925r 34388 essential YOR278W 111 - ACATGTGTATGTTTAATAAG V|44|L V|44|I HEM4 HEMe biosynthesis 275.0 0 0 0 0 0.1990334729795236 P06174 0.9539830088615416 0.9574310183525084 0.6465612053871155 0.8241494297981262 1.679800033569336 2.261199951171875 34.31043122006588 25.0 1.0 no 13854 chrXV_843007 34389 essential YOR278W 190 + ACATTATTATTACCTCTCAA Y|64|* silent|TAC>TAT|Y|64 HEM4 HEMe biosynthesis 275.0 0 0 0 0 0.5987075370647841 P06174 39.80030301863701 25.0 1.0 no 13855 chrXV_843019r 34390 essential YOR278W 205 - TGACTCTACAGTCCTTTGAG E|74|D silent|GAG>GAA|E|74 E|74|Q E|74|K HEM4 HEMe biosynthesis 275.0 0 0 0 0 -0.3635312926093836 P06174 0.94931298494339 0.956179976463318 0.9475290179252625 0.0 0.0 0.0 47.92478946695627 45.0 1.0 no 13856 chrXV_843197r 34392 essential YOR278W 383 - CATCAATAATTATATCAGCA D|134|H D|134|N HEM4 HEMe biosynthesis 275.0 0 0 0 0 1.1263855381976384 P06174 0.9486550092697144 0.956179976463318 0.1163504272699356 0.8018884062767029 -0.4903999865055084 -0.6262000203132629 35.92422006509105 25.0 1.0 no 13857 chrXV_843296 34395 essential YOR278W 479 + CCCAAAGAAACTCCATAGCA P|161|R P|161|L P|161|A P|161|S HEM4 HEMe biosynthesis 275.0 0 0 0 0 0.6781673545063054 P06174 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.7808857560157776 0.21376074850559235 0.20563164353370667 0.17693118751049042 46.09294492849875 45.0 1.0 no 13858 chrXV_843308r 34397 essential YOR278W 494 - TTACTTTTATTCCCTTGCTA V|171|L V|171|I HEM4 HEMe biosynthesis 275.0 0 0 0 0 0.3097406099768769 P06174 0.9539830088615416 0.9574310183525084 0.3760716915130615 0.3329828381538391 47.40868430534647 30.0 1.0 no 13859 chrXV_846473 34398 essential YOR281C 637 - ATCTTCAAAGTCTTCCATCT D|219|H D|219|N E|218|Q E|218|K PLP2 Phosducin-Like Protein 286.0 0 0 0 0 0.0307208786640428 Q12017 0.29190608859062195 0.5549927353858948 0.07746685296297072 0.01999831199645996 46.20242667871589 35.0 0.0 no 13860 chrXV_846546r 34399 essential YOR281C 561 + ACATTAATTGTATATTACCG T|188|R T|188|I PLP2 Phosducin-Like Protein 286.0 0 0 0 0 0.22336511315151408 Q12017 0.0 0.0 36.56055457643299 25.0 0.0 no 13861 chrXV_846547r 34400 essential YOR281C 560 + GACATTAATTGTATATTACC T|188|R T|188|I PLP2 Phosducin-Like Protein 286.0 0 0 0 0 0.4602327494625308 Q12017 0.0 0.0 36.163493320611906 25.0 0.0 no 13862 chrXV_846548r 34401 essential YOR281C 559 + CGACATTAATTGTATATTAC T|188|R T|188|I PLP2 Phosducin-Like Protein 286.0 0 0 0 0 0.2884036382111751 Q12017 0.0 0.0 33.902807433355925 25.0 0.0 no 13863 chrXV_846790r 34403 essential YOR281C 317 + ATACAACAAAGAGGTTACTT Y|107|* silent|TAC>TAT|Y|107 N|108|K silent|AAC>AAT|N|108 PLP2 Phosducin-Like Protein 286.0 0 0 0 0 -3.048158439335982 Q12017 0.9192855954170228 36.407199287154974 30.0 0.0 yes 13864 chrXV_846840r 34404 essential YOR281C 267 + TTACAGGAACGTTCCAAATT Q|91|E Q|91|* PLP2 Phosducin-Like Protein 286.0 0 0 0 0 0.3650535833312871 Q12017 0.5448557138442993 40.97307470686445 35.0 0.0 no 13865 chrXV_846943r 34405 essential YOR281C 164 + ACTAGAAGATAAAGACTTGT L|56|V silent|CTA>TTA|L|56 PLP2 Phosducin-Like Protein 286.0 0 0 0 0 0.24600017942113345 Q12017 0.02460938505828381 34.86573372662508 30.0 0.0 no 13866 chrXV_847001 34406 essential YOR281C 109 - TGCTTCTTCTAACTTTGCAG A|43|P A|43|T E|42|Q E|42|K PLP2 Phosducin-Like Protein 286.0 0 0 0 0 -1.2746269289149084 Q12017 0.026260845363140103 0.04402083158493042 0.08792704343795776 0.2468586266040802 46.64910915050717 40.0 0.0 no 13867 chrXV_847002 34407 essential YOR281C 108 - GCTTCTTCTAACTTTGCAGT A|43|P A|43|T E|42|Q E|42|K PLP2 Phosducin-Like Protein 286.0 0 0 0 0 0.05484179343412965 Q12017 0.026260845363140103 0.04402083158493042 0.08792704343795776 0.2468586266040802 49.43429411196439 40.0 0.0 no 13868 chrXV_851203 34414 essential YOR287C 617 - CCATTTCTTCACGTTCTCCC M|212|I M|212|I E|211|Q E|211|K RRP36 Ribosomal RNA Processing 300.0 0 0 0 0 1.3905827177608632 Q12481 0.6686084866523743 0.6686084866523743 0.5818459987640381 0.8771606087684631 56.23552847359685 50.0 0.0 no 13869 chrXV_851317 34416 essential YOR287C 503 - TTCTTATGATAGAACTATCA R|174|T R|174|K RRP36 Ribosomal RNA Processing 300.0 0 0 0 0 -0.8409969140475959 Q12481 0.0 0.0 36.2227290202991 25.0 0.0 no 13870 chrXV_851395 34420 essential YOR287C 425 - TCCTCGGTATTTCCAGCCCA R|148|T R|148|K R|148|S silent|AGG>AGA|R|148 RRP36 Ribosomal RNA Processing 300.0 0 0 0 0 -0.4306127911313378 Q12481 0.5902222990989685 0.9507045745849608 0.7495319247245789 61.46312014965207 55.00000000000001 0.0 no 13871 chrXV_851412r 34424 essential YOR287C 405 + CCACGAGTCCGAAATATCCC R|137|G R|137|* P|136|R P|136|L RRP36 Ribosomal RNA Processing 300.0 0 0 0 0 -1.084846162995774 Q12481 0.013953217305243015 0.7083099484443665 0.28403836488723755 51.236801277032214 55.00000000000001 0.0 no 13872 chrXV_851426 34425 essential YOR287C 394 - GACTCGTGGTACCCTTTTCT V|138|L V|138|I R|137|P R|137|Q RRP36 Ribosomal RNA Processing 300.0 0 0 0 0 0.15981504906670418 Q12481 0.06370273232460022 0.6750538945198059 0.014942603185772898 0.04424251988530159 55.56456164389414 50.0 0.0 no 13873 chrXV_851442 34426 essential YOR287C 378 - TTCTTGGATGATTGTTCTAC K|132|N silent|AAG>AAA|K|132 RRP36 Ribosomal RNA Processing 300.0 0 0 0 0 -0.6004611276111089 Q12481 0.0 42.98000166907923 35.0 0.0 no 13874 chrXV_851592 34428 essential YOR287C 228 - TCTCTGTATGTAGTTGTGAT R|82|T R|82|K E|83|Q E|83|K RRP36 Ribosomal RNA Processing 300.0 0 0 0 0 -0.24433211240469546 Q12481 0.5070255398750305 1.0 0.5339663028717041 0.8694992065429688 45.42481194695552 35.0 0.0 no 13875 chrXV_851777 34430 essential YOR287C 43 - TCCGTCATCTTCTTCTACGT G|21|R G|21|R G|21|A G|21|E RRP36 Ribosomal RNA Processing 300.0 0 0 0 0 -0.5801125923826153 Q12481 0.22879573702812195 0.22879573702812195 0.37374347448349 0.8224408030509949 52.97816578977012 45.0 0.0 no 13876 chrXV_856484r 34432 high_effect YOR290C 3752 + AGCGTTGCTTAGATCTTTGC A|1252|G A|1252|V SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 0.5822878350326085 P22082 0.0 0.0 50.69397340164125 45.0 0.0 no 13877 chrXV_856517r 34433 high_effect YOR290C 3719 + ATTCGATAACAAATCTACAT F|1241|L silent|TTC>TTT|F|1241 SNF2 Sucrose NonFermenting 1703.0 0 1 0 0 -0.8090320070033394 P22082 0.0 34.45649939965415 25.0 0.0 no 13878 chrXV_856704r 34436 high_effect YOR290C 3532 + TCATTATTTTTGATACTGAC silent|GTC>GTG|V|1178 silent|GTC>GTT|V|1178 SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 -0.2740806863260339 P22082 36.62090966663453 25.0 0.0 no 13879 chrXV_856863r 34442 high_effect YOR290C 3373 + ACATTAATATCAAGTACCTG Y|1125|* silent|TAC>TAT|Y|1125 SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 -0.09690349647940444 P22082 37.725094111234 30.0 0.0 no 13880 chrXV_856898 34443 high_effect YOR290C 3341 - CTTCCATAATATCCATAATT E|1120|Q E|1120|K M|1119|I M|1119|I SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 -1.4544553988209417 P22082 0.0 0.0 0.0 0.0 39.417016398292326 25.0 0.0 no 13881 chrXV_857027 34445 high_effect YOR290C 3212 - TTTCTCTTGTTGGATTGATT E|1077|Q E|1077|K R|1076|T R|1076|K SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 -0.12735490032693594 P22082 0.16486240923404696 0.028089389204978943 0.7015236020088196 1.0 43.64721755792232 30.0 0.0 no 13882 chrXV_857227 34446 high_effect YOR290C 3012 - ACTACCTTCTCAACTTTATC V|1011|L V|1011|M V|1010|L V|1010|I SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 0.010936332273027094 P22082 0.413022130727768 0.02535887435078621 0.0 0.0 44.088376511751854 35.0 0.0 no 13883 chrXV_857443 34448 high_effect YOR290C 2796 - TTCAATAAGGCCCATAATTC L|938|F silent|TTG>TTA|L|938 SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 -0.985647648109352 P22082 0.0 42.578231734892654 35.0 0.0 no 13884 chrXV_857526 34451 high_effect YOR290C 2713 - GTTCAAGGTTAAAGAAAGCT L|910|F silent|TTG>TTA|L|910 SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 -0.18467117961201945 P22082 0.0 38.35401374585348 35.0 0.0 no 13885 chrXV_857453r 34452 high_effect YOR290C 2783 + AAACAACTTGCCAGAATTAT N|929|K silent|AAC>AAT|N|929 N|930|K silent|AAC>AAT|N|930 SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 -0.4618165473224543 P22082 0.0 0.01808919943869114 37.90323228406032 30.0 0.0 no 13886 chrXV_857668r 34454 high_effect YOR290C 2568 + AAACAGGCTAAAATAAGGGC Q|858|E Q|858|* SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 -0.4740074065195363 P22082 0.26650288701057434 37.93500765313189 40.0 0.0 no 13887 chrXV_857622 34455 high_effect YOR290C 2617 - TTCTTTAATAATATACTCAA E|879|Q E|879|K SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 -0.4895240702612005 P22082 0.038767069578170776 0.031235799193382263 31.004425392845288 15.0 0.0 no 13888 chrXV_857968r 34461 high_effect YOR290C 2268 + AAGCAGCCTTCAATATTGGT Q|758|E Q|758|* P|759|A P|759|S SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 0.28571800071351755 P22082 0.0 0.0 0.0 47.749906837908725 40.0 0.0 no 13889 chrXV_858062 34462 high_effect YOR290C 2177 - ATTCTTCATCCTTCATCTTG E|732|Q E|732|K E|731|Q E|731|K SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 0.9867881482426719 P22082 0.5570065975189209 0.8214195370674133 0.4374091923236847 0.6339077949523926 47.28649270009998 35.0 0.0 no 13890 chrXV_858107 34463 high_effect YOR290C 2132 - CCTCCGATGCTTCCTTTATG E|717|Q E|717|K E|717|D silent|GAG>GAA|E|717 SNF2 Sucrose NonFermenting 1703.0 0 1 0 0 0.6732478561114451 P22082 0.2549014687538147 0.3861294686794281 0.4246818423271179 54.082125584456385 50.0 0.0 no 13891 chrXV_858150 34464 high_effect YOR290C 2089 - GTACTTTTGTTGATCTTTCA K|702|N silent|AAG>AAA|K|702 SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 0.3852314774340979 P22082 0.019793754443526268 43.772541222206144 30.0 0.0 no 13892 chrXV_858402 34469 high_effect YOR290C 1837 - TCTTCTATTATATTGATTGA R|619|T R|619|K R|618|T R|618|K SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 -0.2262872716425768 P22082 0.6024197936058044 1.0 0.5702839493751526 1.0 0.873274028301239 -0.3955999910831451 1.602283954620361 0.3698799908161163 1.9700000286102293 0.5225800275802612 1.1363400220870972 -0.02133999951183796 36.23360698692738 20.0 0.0 no 13893 chrXV_858405 34470 high_effect YOR290C 1834 - TCTATTATATTGATTGATGG R|618|T R|618|K SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 -0.5643889814589661 P22082 0.5702839493751526 1.0 1.602283954620361 0.3698799908161163 1.1363400220870972 -0.02133999951183796 35.785329666300406 25.0 0.0 no 13894 chrXV_858619 34471 high_effect YOR290C 1620 - CCTCTTACGGCTTTTTGTAA R|546|T R|546|K G|547|R G|547|S SNF2 Sucrose NonFermenting 1703.0 0 1 0 0 -0.055529487388681166 P22082 0.012624609284102915 0.1725429892539978 0.0 0.0 48.37245379176341 40.0 0.0 no 13895 chrXV_858681r 34473 high_effect YOR290C 1555 + ACGAATGTACGGAATCAACC D|519|E silent|GAC>GAT|D|519 SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 0.03493102269792875 P22082 0.8694575428962708 41.77695288348133 45.0 0.0 no 13896 chrXV_858692r 34474 high_effect YOR290C 1544 + GCTACTAAATGACGAATGTA L|516|V silent|CTA>TTA|L|516 L|517|V silent|CTA>TTA|L|517 SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 -0.076323967926744 P22082 0.2952561378479004 0.35879018902778625 37.910199982795184 35.0 0.0 no 13897 chrXV_858734r 34477 high_effect YOR290C 1502 + TGCATTGAACCTAGATACTA A|502|G A|502|V SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 0.4132837502478929 P22082 0.4095170795917511 0.35228511691093445 42.172851645614685 35.0 0.0 no 13898 chrXV_858828 34480 high_effect YOR290C 1411 - AAACTTTGCATGATCCGAAT K|476|N silent|AAG>AAA|K|476 SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 1.302955825173184 P22082 0.4282435476779938 41.24402415904342 35.0 0.0 no 13899 chrXV_858950 34482 high_effect YOR290C 1289 - CTTCCTTATATTGATCTTGA E|436|Q E|436|K K|435|N silent|AAG>AAA|K|435 SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 0.32802194064767176 P22082 0.4963698387145996 0.8052389025688171 0.6402058005332947 42.77496609849987 30.0 0.0 no 13900 chrXV_859153 34486 high_effect YOR290C 1086 - TTCGCATTATGTACACTAGA silent|GCG>GCC|A|368 silent|GCG>GCA|A|368 A|368|P A|368|T SNF2 Sucrose NonFermenting 1703.0 0 0 0 1 0.1060050766787206 P22082 0.2722672820091248 0.5642754435539246 43.064362408431634 35.0 0.0 no 13901 chrXV_859240r 34487 high_effect YOR290C 996 + ACTAACACTGACAACGTTTC T|333|S T|333|I N|334|K silent|AAC>AAT|N|334 SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 0.0691891281580903 P22082 0.8221563696861267 0.2057153582572937 0.9786450266838074 40.78551923842821 40.0 0.0 no 13902 chrXV_859427r 34491 high_effect YOR290C 809 + GCCTATTCCGTTTGAATTTC P|271|R P|271|L P|271|A P|271|S SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 0.24059664852167706 P22082 0.07455062121152878 0.04028373211622238 0.18891984224319455 0.3136768937110901 48.46193589194604 40.0 0.0 no 13903 chrXV_859464 34493 high_effect YOR290C 775 - ACATTTTAGAGATGTGATTT C|265|S C|265|Y SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 -3.4483903635452715 P22082 0.4245302975177765 1.0 37.70768318756973 25.0 0.0 yes 13904 chrXV_859463 34494 high_effect YOR290C 776 - GACATTTTAGAGATGTGATT C|265|S C|265|Y SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 0.23569772150598264 P22082 0.4245302975177765 1.0 38.70796467844985 30.0 0.0 no 13905 chrXV_859506 34495 high_effect YOR290C 733 - CTCGGCAGTAAACATTGTCA E|251|Q E|251|K A|250|P A|250|T SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 0.06945470620808727 P22082 0.5613422393798828 0.4098348915576935 0.5374357104301453 0.6635711193084717 46.40688125330672 45.0 0.0 no 13906 chrXV_859837 34506 high_effect YOR290C 402 - CCAACCGAAGATTGCCGTTG G|141|R G|141|S V|140|L V|140|I SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 0.5295732107087744 P22082 0.5830838084220886 0.7597276568412781 0.2911600768566132 0.182295486330986 50.211921911679546 55.00000000000001 0.0 no 13907 chrXV_859789 34507 high_effect YOR290C 450 - TCTCCATTGTTTGCTGGTGT G|156|A G|156|E E|157|Q E|157|K SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 -0.4105987913799053 P22082 0.9974578619003296 0.7589638829231262 0.4438070356845856 0.5797163844108582 55.2497160479449 45.0 0.0 no 13908 chrXV_859841r 34509 high_effect YOR290C 395 + GCTACCACAACGGCAATCTT L|133|V silent|CTA>TTA|L|133 P|134|A P|134|S SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 1.0909112629599216 P22082 0.1971288025379181 1.0 0.5844918489456177 50.11449244983436 50.0 0.0 no 13909 chrXV_859870 34510 high_effect YOR290C 369 - TTACCACCATTGCTATTTAA G|129|A G|129|D G|129|R G|129|S SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 0.1759733350479482 P22082 43.79224245109953 30.0 0.0 no 13910 chrXV_859948r 34512 high_effect YOR290C 288 + GCTCCGAATATGCAATTGAA P|98|A P|98|S A|97|G A|97|V SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 -0.5664668516400694 P22082 0.5605199933052063 0.5175969004631042 0.3204682469367981 0.2724858820438385 43.3839299282547 40.0 0.0 no 13911 chrXV_860195 34516 high_effect YOR290C 44 - GCTGCCATCTTAAATAGCAG Q|21|H silent|CAG>CAA|Q|21 W|20|C W|20|* SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 -0.7705964376962744 P22082 0.37152063846588135 0.22642382979393005 47.45186843322023 45.0 0.0 no 13912 chrXV_860199r 34518 high_effect YOR290C 37 + TCAACCGCTGCTATTTAAGA silent|GTC>GTG|V|13 silent|GTC>GTT|V|13 N|14|K silent|AAC>AAT|N|14 SNF2 Sucrose NonFermenting 1703.0 0 0 0 0 0.3465121521472935 P22082 0.542594850063324 45.559074139078795 40.0 0.0 no 13913 chrXV_868374r 34519 essential YOR294W 37 - CACTGGGATAGGCTTTTCAA V|19|L V|19|M RRS1 Regulator of Ribosome Synthesis 203.0 0 0 0 0 -0.971543600594568 Q08746 0.5481169819831848 0.098097525537014 0.16140000522136688 1.0183600187301636 47.75882555459992 45.0 1.0 no 13914 chrXV_868387 34520 essential YOR294W 47 + TATCCCAGTGGTATACGATT I|17|M silent|ATC>ATT|I|17 P|18|A P|18|S RRS1 Regulator of Ribosome Synthesis 203.0 0 0 0 0 0.3807507120175801 Q08746 0.08060044050216675 0.0 0.0 0.27790001034736633 0.904699981212616 1.050819993019104 48.14392485972769 40.0 1.0 no 13915 chrXV_868391r 34521 essential YOR294W 54 - TTACCCAAATCGTATACCAC G|24|A G|24|D G|24|R G|24|S RRS1 Regulator of Ribosome Synthesis 203.0 0 0 0 0 0.09204487323156556 Q08746 0.0 0.0 0.0 0.0 -0.25769999623298645 0.2273399978876114 -0.5031999945640564 -0.8857600092887878 44.9726974856144 40.0 1.0 no 13916 chrXV_868420 34522 essential YOR294W 80 + AGCATTCGATAGTAATGTCT A|28|G A|28|V F|29|L silent|TTC>TTT|F|29 RRS1 Regulator of Ribosome Synthesis 203.0 0 0 0 0 -0.7343445287491401 Q08746 0.007324728649109602 1.0 0.6876465678215027 1.2915199995040894 -0.20090000331401825 0.342739999294281 43.15906576876114 35.0 1.0 no 13917 chrXV_868540 34523 essential YOR294W 200 + ACTACCTATGAAAACAACAA L|68|V silent|CTA>TTA|L|68 P|69|A P|69|S RRS1 Regulator of Ribosome Synthesis 203.0 0 0 0 0 -1.2403663232257942 Q08746 1.0 0.2416437119245529 0.08867501467466354 1.9264999628067017 0.654699981212616 0.8988400101661682 35.02686842136342 30.0 1.0 no 13918 chrXV_868674r 34531 essential YOR294W 337 - AGCTGCAAACTTCTCCCATT A|119|P A|119|T A|118|P A|118|T RRS1 Regulator of Ribosome Synthesis 203.0 0 0 0 0 -0.3551405253448637 Q08746 0.2151798903942108 0.4244547188282013 0.0 0.0 52.058139734698045 45.0 1.0 no 13919 chrXV_868712r 34532 essential YOR294W 375 - ATCTTTCCTGCCCTTTCCTT K|131|N silent|AAG>AAA|K|131 G|130|A G|130|E RRS1 Regulator of Ribosome Synthesis 203.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.2401954796096493 Q08746 0.09921716898679732 0.3164133131504059 0.9978888034820556 60.04680838690052 45.0 1.0 no 13920 chrXV_868752r 34533 essential YOR294W 415 - CCACTTTGGAACCCATTCAC K|144|N silent|AAG>AAA|K|144 W|145|S W|145|* RRS1 Regulator of Ribosome Synthesis 203.0 1 Series([], Name: modification, dtype: object) 0 0 0 -1.1448408075882541 Q08746 0.02055604197084904 0.002582009648904205 51.26130494209463 50.0 1.0 no 13921 chrXV_897239 34536 essential YOR310C 1102 - ATCATAACGCAATGAGACAG D|374|H D|374|N NOP58 NucleOlar Protein of 58 kDa 511.0 0 0 0 0 -4.522177913323363 Q12499 0.9486550092697144 0.956179976463318 0.0 0.0 39.24432745806149 40.0 0.0 yes 13922 chrXV_897303r 34538 essential YOR310C 1035 + TCTCTTGTTGGTCAAGCTAC L|347|V L|347|F S|346|C S|346|F NOP58 NucleOlar Protein of 58 kDa 511.0 0 0 0 0 0.6555414701162571 Q12499 0.9512209892272948 0.9587849974632264 0.945252001285553 0.9294660091400146 0.04170220717787743 0.0056230826303362855 0.0034696294460445642 0.0014553220244124534 49.43436753234232 45.0 0.0 no 13923 chrXV_897342r 34539 essential YOR310C 996 + AAGCATGATACACCAAAGTA H|334|D H|334|Y NOP58 NucleOlar Protein of 58 kDa 511.0 0 0 0 0 0.2877516082421411 Q12499 0.9473130106925964 0.9489949941635132 0.004211038816720247 0.008914283476769924 40.027029626544106 35.0 0.0 no 13924 chrXV_897388 34540 essential YOR310C 953 - CCTTTTCGGCACCTAATATT K|324|N silent|AAG>AAA|K|324 E|323|Q E|323|K NOP58 NucleOlar Protein of 58 kDa 511.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.06037157713900052 Q12499 0.9355990290641784 0.956179976463318 0.9475290179252625 0.0 0.0 0.0 48.7181789896705 40.0 0.0 no 13925 chrXV_897344 34541 essential YOR310C 997 - ATACTTTGGTGTATCATGCT K|338|N silent|AAG>AAA|K|338 NOP58 NucleOlar Protein of 58 kDa 511.0 0 0 0 0 -0.3280202896131029 Q12499 0.9355990290641784 0.0 46.19223626252523 35.0 0.0 no 13926 chrXV_897433r 34545 essential YOR310C 905 + TTCAGGTTCCTTAATTTCCT S|303|* S|303|L NOP58 NucleOlar Protein of 58 kDa 511.0 0 0 0 0 -1.6717281023472783 Q12499 0.9298099875450134 0.0036325389519333844 49.20323328293517 35.0 0.0 no 13927 chrXV_897486 34546 essential YOR310C 855 - CCAACCAACTGAGTCAAGTT G|292|R G|292|S V|291|L V|291|I NOP58 NucleOlar Protein of 58 kDa 511.0 0 0 0 0 -0.16397922570266932 Q12499 0.941340982913971 0.951104998588562 0.9539830088615416 0.9574310183525084 0.0 0.0 0.14542105793952942 0.07501431554555893 46.517805134691855 45.0 0.0 no 13928 chrXV_897490r 34548 essential YOR310C 848 + TGCTCCAAACTTGACTCAGT A|284|G A|284|V P|285|A P|285|S NOP58 NucleOlar Protein of 58 kDa 511.0 0 1 0 0 0.8279231857387459 Q12499 0.9484469890594482 0.9504740238189696 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 48.66130626527956 45.0 0.0 no 13929 chrXV_897517r 34549 essential YOR310C 821 + TTACTTGTCTGCAAGAATGA Y|275|* silent|TAC>TAT|Y|275 NOP58 NucleOlar Protein of 58 kDa 511.0 0 0 0 0 -0.9194463264515924 Q12499 41.16654849504857 35.0 0.0 no 13930 chrXV_897542 34550 essential YOR310C 799 - GGACAACTGTTCTCTGTAAG L|272|F silent|TTG>TTA|L|272 Q|271|H silent|CAG>CAA|Q|271 NOP58 NucleOlar Protein of 58 kDa 511.0 0 0 0 0 -0.3108811410890014 Q12499 0.9587849974632264 0.9570760130882264 0.0 0.04681522026658058 44.21347133417004 45.0 0.0 no 13931 chrXV_897797 34553 essential YOR310C 544 - GTACCATTCTTTACATCTCA W|187|C W|187|* W|187|S W|187|* NOP58 NucleOlar Protein of 58 kDa 511.0 0 0 0 0 -0.9498011570147056 Q12499 0.8858469724655151 0.8858469724655151 0.0 0.0 46.80531588733652 35.0 0.0 no 13932 chrXV_897966 34555 essential YOR310C 375 - GACATACCTGGCAGCAATTC M|131|I M|131|I G|130|A G|130|D NOP58 NucleOlar Protein of 58 kDa 511.0 0 0 0 0 0.2289059142895833 Q12499 0.9553959965705872 0.9553959965705872 0.9499930143356324 0.9446240067481996 0.1534687578678131 0.1534687578678131 0.05878623947501184 0.1788901835680008 49.79820513065129 50.0 0.0 no 13933 chrXV_897709r 34556 essential YOR310C 629 + AACAATGGGTATCAGATCCA T|211|R T|211|I NOP58 NucleOlar Protein of 58 kDa 511.0 0 0 0 0 -0.3663775508087179 Q12499 0.9476869702339172 0.9472420215606691 0.5402923822402954 0.36055988073349 44.40177876162346 40.0 0.0 no 13934 chrXV_898186r 34558 essential YOR310C 152 + CTCTGCAGCTAACGCTTTAG S|52|C S|52|F A|53|G A|53|V NOP58 NucleOlar Protein of 58 kDa 511.0 0 1 0 0 0.14539048053222414 Q12499 0.945252001285553 0.9294660091400146 0.9484469890594482 0.9504740238189696 0.0068267895840108395 0.005037221126258372 0.00927694421261549 0.12408305704593657 49.44036276124194 50.0 0.0 no 13935 chrXV_898264r 34560 essential YOR310C 74 + TTCAAGCTTAATTCAAGACT S|26|* S|26|L S|27|R silent|AGC>AGT|S|27 NOP58 NucleOlar Protein of 58 kDa 511.0 0 1 0 0 -1.2106295341531557 Q12499 0.9298099875450134 0.9417110085487366 0.02697160467505455 0.030268939211964607 38.618735711237825 30.0 0.0 no 13936 chrXV_912839 34561 essential YOR319W 17 + CTCTGGTAATACAGTTTATG S|7|C S|7|F HSH49 Human Sap Homolog 213.0 0 0 0 0 0.5830175670535445 Q99181 0.035735737532377236 0.037891868501901634 40.26762980697515 35.0 1.0 no 13937 chrXV_912840 34562 essential YOR319W 18 + TCTGGTAATACAGTTTATGT S|7|C S|7|F HSH49 Human Sap Homolog 213.0 0 0 0 0 0.10022582939844517 Q99181 0.035735737532377236 0.037891868501901634 40.91728311991046 30.0 1.0 no 13938 chrXV_912910 34563 essential YOR319W 88 + TTCAGATCAACCCTGTTTTA Q|31|E Q|31|* HSH49 Human Sap Homolog 213.0 0 0 0 0 -1.0875969583307632 Q99181 0.011182010173797607 46.53862828449104 35.0 1.0 no 13939 chrXV_912942r 34564 essential YOR319W 123 - GCTTGTAGAACTTTATCTTT A|48|P A|48|T HSH49 Human Sap Homolog 213.0 0 0 0 0 0.4031609317636141 Q99181 0.07481436431407927 1.0 1.0315999984741209 0.9667999744415284 42.08919515365028 30.0 1.0 no 13940 chrXV_913071 34566 essential YOR319W 249 + CGTCAAGTAACCAATTCTAC Q|85|E Q|85|* HSH49 Human Sap Homolog 213.0 0 0 0 0 0.16681163593382015 Q99181 0.02696416899561882 41.46867184825942 40.0 1.0 no 13941 chrXV_913163r 34567 essential YOR319W 344 - CGCTATCTATCGAATCTGCA S|121|T S|121|N D|120|H D|120|N HSH49 Human Sap Homolog 213.0 0 0 0 0 0.2103463398417648 Q99181 0.1936040222644806 0.1308564990758896 0.004145149141550064 0.0202598050236702 47.15528895110674 45.0 1.0 no 13942 chrXV_913247r 34568 essential YOR319W 428 - ACTTTAATTTTCCGTTTGAT K|149|N silent|AAG>AAA|K|149 HSH49 Human Sap Homolog 213.0 0 0 0 0 0.5029185334154388 Q99181 0.13973645865917206 41.09996843176299 25.0 1.0 no 13943 chrXV_913289 34569 essential YOR319W 467 + GGACTTTGAAAAAGCAGATT D|157|E silent|GAC>GAT|D|157 HSH49 Human Sap Homolog 213.0 0 0 0 0 -1.0792056567806194 Q99181 0.06110875681042671 37.76243869904397 35.0 1.0 no 13944 chrXV_925816 34570 essential YOR326W 95 + GTACCACCTGGAGTTACAAT Y|33|* silent|TAC>TAT|Y|33 H|34|D H|34|Y MYO2 MYOsin 1574.0 0 0 0 0 -0.18571493792187774 P19524 0.9473130106925964 0.9489949941635132 0.5921666026115417 0.05546926334500313 48.98300345576763 45.0 1.0 no 13945 chrXV_925819r 34573 essential YOR326W 101 - CTTCCAATTGTAACTCCAGG E|40|Q E|40|K L|39|F silent|TTG>TTA|L|39 MYO2 MYOsin 1574.0 0 0 0 0 0.7504793190325778 P19524 0.956179976463318 0.9475290179252625 0.9587849974632264 0.17118766903877258 0.2649319767951965 0.7432559728622437 47.413968022901145 45.0 1.0 no 13946 chrXV_925857r 34575 essential YOR326W 139 - ATTCAAGTCTTTTGTGTCCA L|52|F silent|TTG>TTA|L|52 MYO2 MYOsin 1574.0 0 0 0 0 -0.03004026360731374 P19524 0.9587849974632264 0.7167024016380309 47.850216976661045 35.0 1.0 no 13947 chrXV_925906 34577 essential YOR326W 185 + TCTTAGAAACCCTCCCATTT L|63|V L|63|F MYO2 MYOsin 1574.0 0 0 0 0 -0.3719808206135601 P19524 0.9512209892272948 0.9587849974632264 0.017311165109276768 0.01486819516867399 50.07206305042348 40.0 1.0 no 13948 chrXV_925919r 34580 essential YOR326W 201 - TCTTCCGTTGCTTCCAAAAT D|74|H D|74|N E|73|Q E|73|K MYO2 MYOsin 1574.0 0 0 0 0 0.08156254364810425 P19524 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.0 0.0 0.14196564257144928 0.0325348936021328 0.13960000872612 0.29868000745773315 48.19015952682832 40.0 1.0 no 13949 chrXV_926151r 34588 essential YOR326W 433 - CATCAACCTATACGCTTCTT L|150|F silent|TTG>TTA|L|150 R|149|S silent|AGG>AGA|R|149 MYO2 MYOsin 1574.0 0 0 0 0 0.5121492221907805 P19524 0.9587849974632264 0.9087679982185364 0.7229613661766052 0.31623032689094543 46.69594981504935 40.0 1.0 no 13950 chrXV_926145r 34589 essential YOR326W 427 - CCTATACGCTTCTTCGGCAA R|149|T R|149|K silent|GCG>GCC|A|147 silent|GCG>GCA|A|147 MYO2 MYOsin 1574.0 0 0 0 0 0.4043013198935925 P19524 0.932735025882721 0.955805003643036 0.3355049192905426 0.3819288611412048 51.82416317339454 50.0 1.0 no 13951 chrXV_926189 34591 essential YOR326W 468 + AATCAAACCATTGTGGTAAG Q|158|E Q|158|* MYO2 MYOsin 1574.0 0 1 0 0 1.3782709696048925 P19524 0.9590039849281312 0.0 38.633692586279146 35.0 1.0 no 13952 chrXV_926335 34594 essential YOR326W 614 + TCTAGCTACAAACCCTATCA L|206|V silent|CTA>TTA|L|206 A|207|G A|207|V MYO2 MYOsin 1574.0 0 0 0 0 0.4640741586126013 P19524 0.9512209892272948 0.9484469890594482 0.9504740238189696 0.011466340161859991 0.018507875502109528 0.005762488581240177 46.793865617132 40.0 1.0 no 13953 chrXV_926400r 34595 essential YOR326W 682 - TTCTAGATACTTACCAAATC E|234|Q E|234|K MYO2 MYOsin 1574.0 0 0 0 0 0.2569689074439854 P19524 0.956179976463318 0.9475290179252625 0.30044350028038025 0.012140389531850815 38.048889154165245 30.0 1.0 no 13954 chrXV_926463 34596 essential YOR326W 742 + TCCGCACATACTTGTTGGAA R|249|G R|249|C I|248|M silent|ATC>ATT|I|248 MYO2 MYOsin 1574.0 0 0 0 0 -0.7770141335332371 P19524 0.8994590044021606 0.8926740288734436 0.9598389863967896 0.0 0.0 0.08995281159877777 48.65168858230714 45.0 1.0 no 13955 chrXV_926464r 34597 essential YOR326W 746 - ACCGTTCCAACAAGTATGTG R|255|P R|255|Q silent|CGG>CGC|R|255 silent|CGG>CGA|R|255 MYO2 MYOsin 1574.0 0 0 0 0 0.09414009578668292 P19524 0.9099509716033936 0.949662983417511 0.0038433035369962454 0.011086917482316494 46.80990097091939 45.0 1.0 no 13956 chrXV_926600 34600 essential YOR326W 879 + TACTTCTACATGAACCAAGG Y|294|* silent|TAC>TAT|Y|294 F|295|L silent|TTC>TTT|F|295 MYO2 MYOsin 1574.0 0 0 0 0 -0.7004647454500861 P19524 0.9387490153312684 0.796036422252655 41.56805110225133 40.0 1.0 no 13957 chrXV_926683 34602 essential YOR326W 962 + GACATTAGTCGGAATCACCA T|322|R T|322|I MYO2 MYOsin 1574.0 0 0 0 0 -0.5413477014456779 P19524 0.9476869702339172 0.9472420215606691 0.06555923819541931 0.01307380013167858 46.61128561393026 45.0 1.0 no 13958 chrXV_926807r 34605 essential YOR326W 1089 - TCGCACGCCAGTTTCAGGTT C|369|S C|369|Y E|370|Q E|370|K MYO2 MYOsin 1574.0 0 0 0 0 -0.8348579024925654 P19524 0.9421560168266296 0.9290120005607604 0.956179976463318 0.9475290179252625 0.30178141593933105 0.006754340138286352 0.44666433334350586 0.7170976400375366 57.55562357469426 55.00000000000001 1.0 no 13959 chrXV_926859r 34607 essential YOR326W 1141 - CTGCTTTTTGGTGACCCATT K|386|N silent|AAG>AAA|K|386 MYO2 MYOsin 1574.0 0 0 0 0 0.5316617600480767 P19524 0.9355990290641784 0.0059267571195960045 53.36959982288926 45.0 1.0 no 13960 chrXV_926871r 34608 essential YOR326W 1153 - CCTTGTAATGATCTGCTTTT R|391|T R|391|K MYO2 MYOsin 1574.0 0 0 0 0 0.1329851128947417 P19524 0.932735025882721 0.955805003643036 0.007282152771949769 0.03742799535393715 45.852012717131394 35.0 1.0 no 13961 chrXV_926940r 34611 essential YOR326W 1222 - AAACTTAGCCACGGAATCTT K|413|N silent|AAG>AAA|K|413 MYO2 MYOsin 1574.0 0 0 0 0 -1.0113965223437322 P19524 0.9355990290641784 0.0 43.907323842854346 40.0 1.0 no 13962 chrXV_926974r 34612 essential YOR326W 1256 - TTTCCACAAGCCAATCGAAA E|425|Q E|425|K silent|GTG>GTC|V|424 silent|GTG>GTA|V|424 MYO2 MYOsin 1574.0 0 0 0 0 -0.3410163157858475 P19524 0.956179976463318 0.9475290179252625 0.5708539485931396 0.8763589859008789 43.937472480527155 40.0 1.0 no 13963 chrXV_927001 34613 essential YOR326W 1280 + CAACACCGTGTTATGCAACC N|428|K silent|AAC>AAT|N|428 T|429|S T|429|I MYO2 MYOsin 1574.0 0 0 0 0 0.5948226860143521 P19524 0.9439849853515624 0.9491789937019348 0.9472420215606691 0.0 0.6642462611198425 0.1702432930469513 48.403980419130725 50.0 1.0 no 13964 chrXV_927006r 34614 essential YOR326W 1288 - CACAGCCGGGTTGCATAACA V|436|L V|436|M A|435|P A|435|T MYO2 MYOsin 1574.0 0 0 0 0 -0.07485210230211893 P19524 0.9539830088615416 0.9587630033493042 0.9573720097541808 0.9523990154266356 0.3790033161640167 0.12021040171384813 0.1985451579093933 0.4149077534675598 52.78543914921824 55.00000000000001 1.0 no 13965 chrXV_927040 34615 essential YOR326W 1319 + TAGCTCATTTATTGGTGTTC S|441|R silent|AGC>AGT|S|441 S|442|* S|442|L MYO2 MYOsin 1574.0 0 0 0 0 -0.21524936762936167 P19524 0.9417110085487366 0.9298099875450134 0.5255618691444397 0.07862475514411926 45.49452139275228 35.0 1.0 no 13966 chrXV_927123r 34617 essential YOR326W 1405 - CTCTTGTTGTAGTTTTTCGT E|475|Q E|475|K MYO2 MYOsin 1574.0 0 0 0 0 0.7068350662471934 P19524 0.956179976463318 0.9475290179252625 0.20243020355701447 0.0144816217944026 47.51077686720078 35.0 1.0 no 13967 chrXV_927273 34618 essential YOR326W 1552 + CACTGCTTGACGAAGAAAGT L|519|V silent|CTG>TTG|L|519 L|520|V L|520|F MYO2 MYOsin 1574.0 0 0 0 0 -1.0865324894741644 P19524 0.9512209892272948 0.9512209892272948 0.9587849974632264 0.0 0.0 0.0 42.09845462316247 45.0 1.0 no 13968 chrXV_927242 34619 essential YOR326W 1521 + GATCTGATTGAAAACAAGTT L|509|V silent|CTG>TTG|L|509 MYO2 MYOsin 1574.0 0 0 0 0 -1.0852262390488172 P19524 0.9512209892272948 0.42071878910064703 34.968495034086125 30.0 1.0 no 13969 chrXV_927300 34620 essential YOR326W 1579 + CTGCTGGTTCCGACGAATCT A|528|G A|528|V MYO2 MYOsin 1574.0 0 0 0 0 0.6845059702266986 P19524 0.9484469890594482 0.9504740238189696 0.1503274291753769 0.10356142371892928 52.635676687703885 55.00000000000001 1.0 no 13970 chrXV_927325r 34621 essential YOR326W 1607 - CCAAAGTTTGATAAAGTTTT L|542|F silent|TTG>TTA|L|542 MYO2 MYOsin 1574.0 0 1 0 0 -0.1612109167027192 P19524 0.9587849974632264 0.5511060953140259 35.88738656080636 25.0 1.0 no 13971 chrXV_927412r 34623 essential YOR326W 1694 - AAGCGACATCTAGAGCATAA A|571|P A|571|T V|570|L V|570|I MYO2 MYOsin 1574.0 0 0 0 0 -0.5070686307193856 P19524 0.9573720097541808 0.9523990154266356 0.9539830088615416 0.9574310183525084 0.04338300973176956 1.0 0.0 0.0 42.179547824326725 40.0 1.0 no 13972 chrXV_927517 34624 essential YOR326W 1796 + GACACTAATAAATATCTTAG T|600|R T|600|I L|601|V silent|CTA>TTA|L|601 MYO2 MYOsin 1574.0 0 0 0 0 0.7503859961751089 P19524 0.9476869702339172 0.9472420215606691 0.9512209892272948 0.0058678723871707925 0.16976583003997806 0.1732719987630844 31.383368920918144 25.0 1.0 no 13973 chrXV_927518 34625 essential YOR326W 1797 + ACACTAATAAATATCTTAGA L|601|V silent|CTA>TTA|L|601 T|600|R T|600|I MYO2 MYOsin 1574.0 0 0 0 0 -0.017306404781739382 P19524 0.9512209892272948 0.9476869702339172 0.9472420215606691 0.1732719987630844 0.0058678723871707925 0.16976583003997806 31.383368920918198 20.0 1.0 no 13974 chrXV_927654r 34627 essential YOR326W 1936 - AATCAAAGATTGCTTAAACA L|651|F silent|TTG>TTA|L|651 MYO2 MYOsin 1574.0 0 0 0 0 -0.627504830602339 P19524 0.9587849974632264 0.0 33.466402839521606 25.0 1.0 no 13975 chrXV_927836r 34630 essential YOR326W 2118 - TCTTCAAAAGTCCACCTAGA E|713|Q E|713|K E|712|Q E|712|K MYO2 MYOsin 1574.0 0 0 0 0 0.5695402966619996 P19524 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.02338667400181293 0.02241947501897812 0.5503378510475159 0.8042546510696411 45.55383522284735 40.0 1.0 no 13976 chrXV_927961 34632 essential YOR326W 2240 + GATCCTAGATGCTACTGTAA I|748|M silent|ATC>ATT|I|748 L|749|V silent|CTA>TTA|L|749 MYO2 MYOsin 1574.0 0 0 0 0 -2.160484360140352 P19524 0.9598389863967896 0.9512209892272948 0.008325140923261642 0.1378536820411682 45.42932191194956 40.0 1.0 yes 13977 chrXV_927964r 34633 essential YOR326W 2246 - TGTCCTTTACAGTAGCATCT D|755|H D|755|N K|754|N silent|AAG>AAA|K|754 MYO2 MYOsin 1574.0 0 0 0 0 -0.40916090223114543 P19524 0.9486550092697144 0.956179976463318 0.9355990290641784 0.006659851409494878 0.026855619624257088 0.4849953055381775 50.46442320346466 40.0 1.0 no 13978 chrXV_927983 34634 essential YOR326W 2262 + GACAAATCCAAGTACCAGAT D|755|E silent|GAC>GAT|D|755 MYO2 MYOsin 1574.0 0 0 0 0 -0.1629328174254891 P19524 0.9532920122146606 0.2541828155517578 42.79145053700381 40.0 1.0 no 13979 chrXV_928219 34636 essential YOR326W 2498 + TAACTGTGCAACTTTATTAC N|834|K silent|AAC>AAT|N|834 MYO2 MYOsin 1574.0 0 0 0 0 0.3629354019027248 P19524 0.9439849853515624 1.0 0.02380399964749813 37.84174197737809 30.0 1.0 no 13980 chrXV_928264r 34638 essential YOR326W 2546 - ATACGCTGAACACATTGGCA V|855|L V|855|I S|854|T S|854|N MYO2 MYOsin 1574.0 0 0 0 0 0.3272768376139874 P19524 0.9539830088615416 0.9574310183525084 0.9512869715690612 0.9536849856376648 0.3571585714817047 0.4500203728675842 0.5712339878082275 0.4814606606960297 -0.4757899940013886 -0.2088479995727539 0.1879059970378876 0.06612200289964676 46.50128516848668 45.0 1.0 no 13981 chrXV_928269r 34639 essential YOR326W 2551 - TCTCAATACGCTGAACACAT L|856|F silent|TTG>TTA|L|856 R|857|T R|857|K MYO2 MYOsin 1574.0 0 0 0 0 -0.25980279708936643 P19524 0.9587849974632264 0.932735025882721 0.955805003643036 0.15221577882766724 0.586523175239563 0.925010859966278 0.5722259879112244 -0.10648199915885924 -0.1058100014925003 42.71443917290628 40.0 1.0 no 13982 chrXV_928406r 34640 essential YOR326W 2688 - GTGCGTAAAAATCTCGATCT R|902|P R|902|H MYO2 MYOsin 1574.0 0 0 0 0 0.2983501183941963 P19524 0.9099509716033936 0.9570810198783876 0.2580409348011017 0.14764006435871124 41.75641909504742 40.0 1.0 no 13983 chrXV_928450r 34641 essential YOR326W 2732 - CTCTTCTTCTGATCAAAGAT R|917|T R|917|K R|916|T R|916|K MYO2 MYOsin 1574.0 0 0 0 0 -0.2141120592194309 P19524 0.932735025882721 0.955805003643036 0.932735025882721 0.955805003643036 0.016122838482260704 1.0 0.11498325318098067 0.7796696424484253 41.6017860232364 35.0 1.0 no 13984 chrXV_928570 34643 essential YOR326W 2849 + GACGCAGAATCTAGCATCCA T|951|R T|951|M Q|952|E Q|952|* MYO2 MYOsin 1574.0 0 0 0 0 -3.0447099381665064 P19524 0.9476869702339172 0.9502379894256592 0.9590039849281312 0.007041910663247109 0.003255478339269757 0.0875031128525734 50.06788154394542 50.0 1.0 yes 13985 chrXV_928587r 34644 essential YOR326W 2869 - TTCTTTATTTTCTTTGACCT E|963|Q E|963|K MYO2 MYOsin 1574.0 0 0 0 0 0.926939847958824 P19524 0.956179976463318 0.9475290179252625 0.5409596562385559 0.8498082756996155 43.62740900347478 25.0 1.0 no 13986 chrXV_928656r 34645 essential YOR326W 2938 - TTCTAATGTCTCTTGTAACT E|986|Q E|986|K MYO2 MYOsin 1574.0 0 0 0 0 0.17283918107901772 P19524 0.956179976463318 0.9475290179252625 0.26356759667396545 0.3227189779281616 41.11483672253229 30.0 1.0 no 13987 chrXV_928897r 34648 essential YOR326W 3179 - GCAAGTCTCCGTTTAATGTC L|1066|F silent|TTG>TTA|L|1066 D|1065|H D|1065|N MYO2 MYOsin 1574.0 0 0 0 0 1.421722165782246 P19524 0.9587849974632264 0.9486550092697144 0.956179976463318 0.01772306300699711 0.14905892312526706 0.5402135848999023 48.686051956911 45.0 1.0 no 13988 chrXV_928921 34649 essential YOR326W 3200 + AAACGAAGTTAAATCTTTAA N|1068|K silent|AAC>AAT|N|1068 MYO2 MYOsin 1574.0 0 1 0 0 0.5670251955836538 P19524 0.9439849853515624 0.9609866738319396 29.972544255622612 20.0 1.0 no 13989 chrXV_928958 34650 essential YOR326W 3237 + TTACAAACTGCCATGTCGCT Q|1081|E Q|1081|* MYO2 MYOsin 1574.0 0 0 0 0 -0.13631988026470093 P19524 0.9590039849281312 1.0 48.65868446052025 45.0 1.0 no 13990 chrXV_928999 34651 essential YOR326W 3278 + ACTACCTCAAACACCATTAA L|1094|V silent|CTA>TTA|L|1094 P|1095|A P|1095|S MYO2 MYOsin 1574.0 0 1 0 0 0.18593826189422927 P19524 0.9512209892272948 0.9562489986419678 0.9498909711837769 0.3826375901699066 0.3850687146186829 0.8416030406951904 42.09006617468367 35.0 1.0 no 13991 chrXV_929003r 34652 essential YOR326W 3285 - ACATCCTTTAATGGTGTTTG V|1102|L V|1102|I D|1101|H D|1101|N MYO2 MYOsin 1574.0 0 1 0 0 0.4465133453068917 P19524 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 0.3139818608760834 0.1933852583169937 0.14594843983650208 0.5929388403892517 44.012714517699 35.0 1.0 no 13992 chrXV_929012r 34654 essential YOR326W 3294 - CCTCCCATTACATCCTTTAA G|1104|A G|1104|E G|1105|R G|1105|S MYO2 MYOsin 1574.0 0 0 0 0 0.7042121931022224 P19524 0.9499930143356324 0.9438679814338684 0.941340982913971 0.951104998588562 0.8538376092910767 0.7525691986083984 0.5429995656013489 0.778757631778717 51.06084512108424 40.0 1.0 no 13993 chrXV_929105 34655 essential YOR326W 3384 + TCTAGATCTACTCCATCGTC S|1129|C S|1129|F MYO2 MYOsin 1574.0 0 1 0 0 -0.2527350294565873 P19524 0.945252001285553 0.9294660091400146 0.05612870305776596 0.06225777044892311 49.420728855780624 45.0 1.0 no 13994 chrXV_929251r 34658 essential YOR326W 3533 - GTACTTCGAATCCCTTTAAC V|1184|L V|1184|I E|1183|Q E|1183|K MYO2 MYOsin 1574.0 0 0 0 0 1.010547782083985 P19524 0.9539830088615416 0.9574310183525084 0.956179976463318 0.9475290179252625 0.021446177735924717 1.0 0.018370982259511948 1.0 1.253999948501587 0.2833999991416931 -0.7135999798774719 -0.8835999965667725 -0.15262000262737274 -0.4928799867630005 44.98640110616998 40.0 1.0 no 13995 chrXV_937403 34659 essential YOR329C 1927 - TATCATTGTTGCTTGATTAT M|648|I M|648|I 0 0 0 0 0.8682935469385575 P34758 0.9553959965705872 0.9553959965705872 0.4654629528522492 0.4654629528522492 40.45159595392329 25.0 0.0 no 13996 chrXV_937496r 34660 essential YOR329C 1831 + ATACGATCCCGCAGCACCAA T|612|R T|612|M 0 0 0 0 -0.4738707563475028 P34758 0.9476869702339172 0.9502379894256592 0.6197601556777954 0.10515216737985612 54.23036792567075 55.00000000000001 0.0 no 13997 chrXV_937617r 34663 essential YOR329C 1710 + AACAATGTTCGGATTAATAA N|571|K silent|AAC>AAT|N|571 0 0 0 0 0.588285481522611 P34758 0.9439849853515624 0.905892014503479 33.80274595060581 25.0 0.0 no 13998 chrXV_937625 34664 essential YOR329C 1705 - AATCCGAACATTGTTAGAGT silent|CGG>CGC|R|574 silent|CGG>CGA|R|574 R|574|P R|574|Q 0 0 0 0 0.07567347076940477 P34758 0.9099509716033936 0.949662983417511 0.2901236116886139 0.7161051034927368 41.64797155283117 35.0 0.0 no 13999 chrXV_937628r 34665 essential YOR329C 1699 + ACACCTACTCTAACAATGTT T|568|S T|568|I H|567|Q silent|CAC>CAT|H|567 0 1 0 0 -0.7188737913756336 P34758 0.9491789937019348 0.9472420215606691 0.9588389992713928 0.6119369864463806 0.21758276224136355 0.6815193891525269 42.6064976798848 35.0 0.0 no 14000 chrXV_937699r 34666 essential YOR329C 1628 + TCAACAGCAACCTTACCAAG Q|544|E Q|544|* Q|545|E Q|545|* 0 0 0 0 -0.7011124344805622 P34758 0.9590039849281312 0.9590039849281312 0.7376127839088441 0.8354389667510986 45.177612590596645 45.0 0.0 no 14001 chrXV_937743 34667 essential YOR329C 1587 - TTCGGAGAATTCAGAAATGC silent|CCG>CCC|P|535 silent|CCG>CCA|P|535 0 0 0 0 -1.0160260392605294 P34758 39.764884550277095 40.0 0.0 no 14002 chrXV_937767r 34668 essential YOR329C 1560 + TCTTCATCTCCACAAAGTAC S|521|C S|521|F S|522|* S|522|L 0 0 0 0 0.9567780779049568 P34758 0.945252001285553 0.9294660091400146 0.9298099875450134 0.17617560923099518 0.7037042379379272 0.15821097791194916 44.72646974936123 40.0 0.0 no 14003 chrXV_937806 34670 essential YOR329C 1524 - GCCTGAAACATCGAAGATAC Q|514|H silent|CAG>CAA|Q|514 A|515|P A|515|T 0 0 0 0 0.03347200840505085 P34758 0.9570760130882264 0.9573720097541808 0.9523990154266356 0.1588403731584549 0.34243327379226685 0.7709293365478516 41.80098196703301 45.0 0.0 no 14004 chrXV_937807r 34672 essential YOR329C 1520 + CCCAGTATCTTCGATGTTTC P|508|R P|508|L P|508|A P|508|S 0 0 0 0 0.6995869195889186 P34758 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.2882784008979797 0.2177281528711319 0.4895825386047363 0.8468679785728455 50.94161974492982 45.0 0.0 no 14005 chrXV_937878r 34674 essential YOR329C 1449 + CCTTTGAAACCTACCGCCAC P|484|R P|484|L 0 0 0 0 -1.423510098505432 P34758 0.9432820081710817 0.9430609941482544 0.011739681474864485 0.016116928309202194 52.73257009715263 55.00000000000001 0.0 no 14006 chrXV_937911 34675 essential YOR329C 1419 - CCAGAGTTTGTAACTGTTTC G|480|R G|480|R 0 0 0 0 1.4904339130142632 P34758 0.941340982913971 0.941340982913971 0.5247464179992676 0.5247464179992676 45.55117616342699 40.0 0.0 no 14007 chrXV_937923 34677 essential YOR329C 1407 - ACTGTTTCTGGTGTACTCGA V|476|L V|476|I 0 0 0 0 0.2263012871041475 P34758 0.9539830088615416 0.9574310183525084 0.5894622206687927 0.4412222802639008 50.259119314145096 45.0 0.0 no 14008 chrXV_937998 34679 essential YOR329C 1332 - CCCGTTGCTGTTGGTTTTAA silent|ACG>ACC|T|450 silent|ACG>ACA|T|450 G|451|R G|451|S 0 0 0 1 0.21176417413858006 P34758 0.941340982913971 0.951104998588562 0.0 0.0 52.61630735588199 45.0 0.0 no 14009 chrXV_938083r 34680 essential YOR329C 1244 + CACAGGTTCAGCTAATCACC T|416|R T|416|I 1 Series([], Name: modification, dtype: object) 0 0 0 -0.5561246939943194 P34758 0.9476869702339172 0.9472420215606691 0.0 0.0 49.99809494139482 50.0 0.0 no 14010 chrXV_938294 34683 essential YOR329C 1036 - CTCAGTTTCTTGTTGTTCGC E|352|Q E|352|K 0 0 0 0 0.5877711095471823 P34758 0.956179976463318 0.9475290179252625 0.05178401619195938 0.04580949991941452 51.618142104822034 45.0 0.0 no 14011 chrXV_938295 34684 essential YOR329C 1035 - TCAGTTTCTTGTTGTTCGCT E|352|Q E|352|K 0 0 0 0 -0.1510238864870173 P34758 0.956179976463318 0.9475290179252625 0.05178401619195938 0.04580949991941452 51.618142104822034 40.0 0.0 no 14012 chrXV_938395r 34686 essential YOR329C 932 + TTCTAATAATGACAGTCCTT S|312|C S|312|F 1 Series([], Name: modification, dtype: object) 0 0 0 0.4727181236089471 P34758 0.945252001285553 0.9294660091400146 0.0534474328160286 0.05294641479849816 40.58803018383009 30.0 0.0 no 14013 chrXV_938686 34690 essential YOR329C 644 - CTTCGTGATTCTCACTACTT E|221|Q E|221|K 0 0 0 0 0.6348474669281843 P34758 0.956179976463318 0.9475290179252625 0.5993546843528748 0.7652394771575928 46.937049615152425 40.0 0.0 no 14014 chrXV_938740r 34693 essential YOR329C 587 + ACCTCTAAGACGCATGATCT P|197|R P|197|L P|197|A P|197|S 0 0 0 0 -1.1521678471221999 P34758 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 47.86771131794506 45.0 0.0 no 14015 chrXV_938917 34694 essential YOR329C 413 - TCAATCTTACTAGTTTTCCA L|144|F silent|TTG>TTA|L|144 R|143|T R|143|K 0 0 0 0 -0.07390552352445401 P34758 0.9587849974632264 0.932735025882721 0.955805003643036 0.0 0.017674151808023453 0.35229042172431946 43.68884041375446 30.0 0.0 no 14016 chrXV_938978r 34695 essential YOR329C 349 + AACTTACCCATGAAGAAATA L|118|V L|118|F T|119|S T|119|I 0 0 0 0 0.4586694863617933 P34758 0.9512209892272948 0.9587849974632264 0.9491789937019348 0.9472420215606691 0.0 0.0 0.4952391982078552 0.024204334244132042 37.38480617973863 30.0 0.0 no 14017 chrXV_938739 34697 essential YOR329C 591 - TCCAAGATCATGCGTCTTAG L|203|F silent|TTG>TTA|L|203 E|204|Q E|204|K 0 0 0 0 1.6322484675454632 P34758 0.9587849974632264 0.956179976463318 0.9475290179252625 0.025858264416456226 0.4097059965133667 0.2812442481517792 47.38259351834381 45.0 0.0 no 14018 chrXV_939072 34698 essential YOR329C 258 - GTTCGTACCTCCCCATTAGG R|92|P R|92|Q 0 0 0 0 0.6692613216311721 P34758 0.9099509716033936 0.949662983417511 0.24532151222229004 0.537297248840332 58.05597613184676 55.00000000000001 0.0 no 14019 chrXV_939100r 34699 essential YOR329C 227 + TAACGTGAGCTCTCCTCAAA N|77|K silent|AAC>AAT|N|77 0 1 0 0 0.5628050143495049 P34758 0.9439849853515624 0.9714582562446594 46.696674409745704 45.0 0.0 no 14020 chrXV_939202r 34700 essential YOR329C 125 + TCCACATGATTCCAGCTTTT P|43|R P|43|L P|43|A P|43|S 0 0 0 0 0.9370569626688656 P34758 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.3894192576408386 0.22457808256149286 0.9763524532318116 0.97176855802536 51.10687834044597 40.0 0.0 no 14021 chrXV_939239 34701 essential YOR329C 91 - ACCAAAATCAAAAGACACAC G|37|R G|37|S G|37|A G|37|D 0 0 0 0 0.3669206805656871 P34758 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 34.813069344037444 35.0 0.0 no 14022 chrXV_939277 34704 essential YOR329C 53 - TCGATGGCCTCTTTTCTGCT silent|TCG>TCC|S|24 silent|TCG>TCA|S|24 0 0 0 0 0.7528821303599944 P34758 56.48846507409462 50.0 0.0 no 14023 chrXV_939303 34705 essential YOR329C 27 - CCGCTGCTTAAGTCCAATCC S|15|T S|15|N G|16|R G|16|R 0 0 0 0 -0.6338571870292959 P34758 0.9512869715690612 0.9536849856376648 0.941340982913971 0.941340982913971 0.6829226016998291 0.6723127961158752 0.4798220098018646 0.4798220098018646 54.81311229642728 55.00000000000001 0.0 no 14024 chrXV_943748 34708 high_effect YOR332W 92 + AGCGAAGGAAATCCAATTGA A|32|G A|32|V VMA4 Vacuolar Membrane Atpase 233.0 0 0 0 0 0.6103339839547871 P22203 0.9484469890594482 0.9504740238189696 0.02187155373394489 0.0069073005579411975 1.0267800092697144 -0.06976000219583511 0.8426200151443481 -0.2887200117111206 1.6789000034332275 0.788860023021698 40.99821416898351 40.0 1.0 no 14025 chrXV_943760r 34709 high_effect YOR332W 107 - ACTCTTGGTCAGCCTTCAAT E|42|Q E|42|K E|42|D silent|GAG>GAA|E|42 VMA4 Vacuolar Membrane Atpase 233.0 0 1 0 0 -0.04267087524480578 P22203 0.956179976463318 0.9475290179252625 0.94931298494339 0.014611366204917431 0.011332906782627106 0.15624383091926575 -0.05217999964952469 -0.5741000175476074 0.3822599947452545 0.03613999858498573 -0.29603999853134155 0.4875600039958954 52.548185113342065 45.0 1.0 no 14026 chrXV_944179r 34719 high_effect YOR332W 526 - GTCTTTGTTCAAGTAATCAT D|182|H D|182|N VMA4 Vacuolar Membrane Atpase 233.0 0 0 0 0 -0.7740777076091463 P22203 0.9486550092697144 0.956179976463318 0.012832625769078732 0.032448112964630134 0.2981399893760681 0.0911799967288971 41.192896902803795 30.0 1.0 no 14027 chrXV_944115 34720 high_effect YOR332W 459 + GACGACATTATGCGTGAGTA D|154|E silent|GAC>GAT|D|154 D|155|E silent|GAC>GAT|D|155 VMA4 Vacuolar Membrane Atpase 233.0 0 1 0 0 -1.691098977589426 P22203 0.9532920122146606 0.9532920122146606 1.0 1.0 -0.4100599884986877 -0.5254200100898743 45.392485785837444 45.0 1.0 no 14028 chrXV_946953 34721 essential YOR335C 2137 - GCAAAATTCAATAGAATACT C|719|S C|719|Y ALA1 ALAnyl-tRNA synthetase 958.0 0 0 0 0 -0.6015892025043255 P40825 32.706607656056796 25.0 0.0 no 14029 chrXV_947023r 34725 essential YOR335C 2064 + CCAGTTCGTGTAGTTTCTGT P|689|R P|689|L R|691|G R|691|C ALA1 ALAnyl-tRNA synthetase 958.0 0 0 0 0 0.5517742958021044 P40825 53.16476950679697 45.0 0.0 no 14030 chrXV_947073 34727 essential YOR335C 2017 - ACGAACACCATCAATGGATT R|679|P R|679|H V|678|L V|678|I ALA1 ALAnyl-tRNA synthetase 958.0 0 0 0 0 -0.7364360872320158 P40825 42.77659423304641 40.0 0.0 no 14031 chrXV_947080r 34728 essential YOR335C 2007 + GACTTGGCCAAATCCATTGA D|670|E silent|GAC>GAT|D|670 ALA1 ALAnyl-tRNA synthetase 958.0 0 1 0 0 0.32922795464731563 P40825 48.453424665643404 45.0 0.0 no 14032 chrXV_947195r 34729 essential YOR335C 1892 + ATTCGATTTCTCTCATAAAA F|632|L silent|TTC>TTT|F|632 ALA1 ALAnyl-tRNA synthetase 958.0 0 1 0 0 0.4977880032014614 P40825 36.54172922747972 25.0 0.0 no 14033 chrXV_947276r 34730 essential YOR335C 1811 + TATCTTAAACTTTGCTCTGA I|605|M silent|ATC>ATT|I|605 ALA1 ALAnyl-tRNA synthetase 958.0 0 0 0 0 0.8472997776705592 P40825 40.36275665030507 30.0 0.0 no 14034 chrXV_947305 34731 essential YOR335C 1785 - CCAGTATGATTGTTCTTAAT G|602|R G|602|S ALA1 ALAnyl-tRNA synthetase 958.0 0 0 0 0 -0.22729353596098706 P40825 41.56888205946956 30.0 0.0 no 14035 chrXV_947497r 34734 essential YOR335C 1590 + ACATGTTTCTACGCCGAACA T|531|R T|531|I ALA1 ALAnyl-tRNA synthetase 958.0 0 0 0 0 0.05949249671885226 P40825 47.848371553197296 45.0 0.0 no 14036 chrXV_947580 34736 essential YOR335C 1510 - ACCGTCATGCAGTTTCAAAA G|510|R G|510|S G|510|A G|510|D ALA1 ALAnyl-tRNA synthetase 958.0 0 0 0 0 -0.8299567111735571 P40825 45.31620938435998 40.0 0.0 no 14037 chrXV_947736 34738 essential YOR335C 1354 - TGCTTCGTATGACTCTTGTT A|458|P A|458|T E|457|Q E|457|K ALA1 ALAnyl-tRNA synthetase 958.0 0 0 0 0 -0.13308539453111415 P40825 48.652647176049186 40.0 0.0 no 14038 chrXV_947807 34741 essential YOR335C 1283 - TCAATTCAGTCAAGTCGACT L|434|F silent|TTG>TTA|L|434 E|433|Q E|433|K ALA1 ALAnyl-tRNA synthetase 958.0 0 0 0 0 -0.9442876187565016 P40825 44.17982364643382 40.0 0.0 no 14039 chrXV_947936r 34743 essential YOR335C 1151 + AGCTTCTTTCGCTAAGACCT A|385|G A|385|V S|386|C S|386|F ALA1 ALAnyl-tRNA synthetase 958.0 0 0 0 0 0.4588722941485953 P40825 51.39101019598907 45.0 0.0 no 14040 chrXV_947996r 34746 essential YOR335C 1091 + TATCTTTCCCGAATTAGCCA I|365|M silent|ATC>ATT|I|365 ALA1 ALAnyl-tRNA synthetase 958.0 0 0 0 0 0.7551266325261934 P40825 49.84701642442861 40.0 0.0 no 14041 chrXV_948026r 34747 essential YOR335C 1061 + GGCTCCAACTTTAATTTCTC A|355|G A|355|V P|356|A P|356|S ALA1 ALAnyl-tRNA synthetase 958.0 0 0 0 0 0.2878392016646624 P40825 46.759322615974845 40.0 0.0 no 14042 chrXV_948133 34749 essential YOR335C 957 - TATCCTCTACCTTCATTGTT G|325|A G|325|E G|325|R G|325|R ALA1 ALAnyl-tRNA synthetase 958.0 0 0 0 0 -2.836326940900346 P40825 49.507497071251116 35.0 0.0 yes 14043 chrXV_948136r 34750 essential YOR335C 951 + GTTCCAAACAATGAAGGTAG P|319|A P|319|S P|319|R P|319|L ALA1 ALAnyl-tRNA synthetase 958.0 0 0 0 0 -0.9983043259128918 P40825 39.76736330119928 40.0 0.0 no 14044 chrXV_948256r 34753 essential YOR335C 831 + ACTTCAGTTAGACCATATTC T|278|S T|278|I S|279|* S|279|L ALA1 ALAnyl-tRNA synthetase 958.0 0 0 0 0 1.0983764420115394 P40825 43.85883174608664 35.0 0.0 no 14045 chrXV_948266 34754 essential YOR335C 824 - GTCTAACTGAAGTGATTTCT R|281|T R|281|K V|280|L V|280|I ALA1 ALAnyl-tRNA synthetase 958.0 0 0 0 0 0.1336974995888598 P40825 41.39131291098312 35.0 0.0 no 14046 chrXV_948370r 34757 essential YOR335C 717 + AAGCATATCGACACAGGTAT H|241|D H|241|Y ALA1 ALAnyl-tRNA synthetase 958.0 0 1 0 0 -1.0134221458650399 P40825 43.55874488216722 40.0 0.0 no 14047 chrXV_948446r 34761 essential YOR335C 641 + TGTCTTGGAAGTTTGGAATT silent|GTC>GTG|V|215 silent|GTC>GTT|V|215 ALA1 ALAnyl-tRNA synthetase 958.0 0 0 0 0 -1.1205948624818067 P40825 42.27653002454247 35.0 0.0 no 14048 chrXV_948452 34762 essential YOR335C 638 - TCCAAACTTCCAAGACATCA W|219|S W|219|* W|219|C W|219|* ALA1 ALAnyl-tRNA synthetase 958.0 0 0 0 0 -0.903448804900552 P40825 44.77804934087652 40.0 0.0 no 14049 chrXV_948479r 34763 essential YOR335C 608 + TGCTGCTTCCTTGGTTAATA A|204|G A|204|V A|205|G A|205|V ALA1 ALAnyl-tRNA synthetase 958.0 0 0 0 0 1.6649116946469062 P40825 49.99195067667414 40.0 0.0 no 14050 chrXV_948584 34765 essential YOR335C 506 - TTGCATTACCAGGTAATATA A|175|P A|175|T ALA1 ALAnyl-tRNA synthetase 958.0 0 0 0 0 -0.3776608362180517 P40825 41.58275916145601 30.0 0.0 no 14051 chrXV_948620 34767 essential YOR335C 470 - CAACATTTTTCCATAGTTCA V|163|L V|163|I ALA1 ALAnyl-tRNA synthetase 958.0 0 1 0 0 0.03961080171049355 P40825 42.52168041907919 30.0 0.0 no 14052 chrXV_948621 34768 essential YOR335C 469 - AACATTTTTCCATAGTTCAC V|163|L V|163|I ALA1 ALAnyl-tRNA synthetase 958.0 0 1 0 0 -0.4128818025098239 P40825 41.60971678772381 30.0 0.0 no 14053 chrXV_948630r 34769 essential YOR335C 457 + ATACTGAAGCCCGTGAACTA T|154|S T|154|I ALA1 ALAnyl-tRNA synthetase 958.0 0 0 0 0 0.10586490455750804 P40825 46.96317437111867 45.0 0.0 no 14054 chrXV_948718r 34770 essential YOR335C 369 + ACTTTGTTGACTGAAGTATA T|124|S T|124|I ALA1 ALAnyl-tRNA synthetase 958.0 0 0 0 0 0.6435183238768175 P40825 39.245411015835366 30.0 0.0 no 14055 chrXV_948832r 34772 essential YOR335C 255 + CACAACGATTTAGAAGATGT H|86|Q silent|CAC>CAT|H|86 N|87|K silent|AAC>AAT|N|87 ALA1 ALAnyl-tRNA synthetase 958.0 0 1 0 0 -0.2328106552732225 P40825 37.61825859983429 35.0 0.0 no 14056 chrXV_948862r 34773 essential YOR335C 225 + TCTCAAAAGTGTATCAGAGC Q|77|E Q|77|* S|76|C S|76|F ALA1 ALAnyl-tRNA synthetase 958.0 0 1 0 0 -0.5435357671829293 P40825 0.9590039849281312 0.0 41.46064128409704 40.0 0.0 no 14057 chrXV_948894r 34775 essential YOR335C 193 + CCGATTTCTACACCTTGAAA silent|TCC>TCG|S|65 silent|TCC>TCT|S|65 ALA1 ALAnyl-tRNA synthetase 958.0 0 0 0 0 -0.5822890630786774 P40825 44.56775135050913 40.0 0.0 no 14058 chrXV_948945 34777 essential YOR335C 145 - AGGCTTGTATTGGTTCATAC K|54|N silent|AAG>AAA|K|54 ALA1 ALAnyl-tRNA synthetase 958.0 0 0 0 0 -2.769240439603135 P40825 47.21440485747435 40.0 0.0 yes 14059 chrXV_949844 34780 essential YOR336W 71 + TGGCATACCCGAATCTGCTC silent|GGC>GGG|G|25 silent|GGC>GGT|G|25 KRE5 Killer toxin REsistant 1365.0 0 0 0 0 1.4538049829068065 P22023 53.83483415239618 55.00000000000001 1.0 no 14060 chrXV_949929r 34782 essential YOR336W 159 - TCATCCAAACCGGTAACCAA D|60|H D|60|N D|59|H D|59|N KRE5 Killer toxin REsistant 1365.0 0 0 0 0 0.16874118652056058 P22023 0.014109469018876553 0.03231778740882873 0.015403661876916884 0.037878844887018204 46.73169439114843 45.0 1.0 no 14061 chrXV_949939r 34783 essential YOR336W 169 - ATCAATCTCGTCATCCAAAC D|63|H D|63|N E|61|D silent|GAG>GAA|E|61 KRE5 Killer toxin REsistant 1365.0 0 0 0 0 0.3197116508808089 P22023 0.05828602239489555 0.19492757320404053 0.9544910192489624 43.41972267521476 40.0 1.0 no 14062 chrXV_949981 34784 essential YOR336W 208 + CGCTAACTTCCAATGTATTA L|71|V silent|CTA>TTA|L|71 T|72|S T|72|I KRE5 Killer toxin REsistant 1365.0 0 0 0 0 -0.019457871379497185 P22023 0.4976572692394257 0.011732748709619044 0.3958475887775421 42.773195847277115 35.0 1.0 no 14063 chrXV_949982 34785 essential YOR336W 209 + GCTAACTTCCAATGTATTAA L|71|V silent|CTA>TTA|L|71 T|72|S T|72|I KRE5 Killer toxin REsistant 1365.0 0 0 0 0 0.2624459650140598 P22023 0.4976572692394257 0.011732748709619044 0.3958475887775421 40.09114542453523 30.0 1.0 no 14064 chrXV_950092r 34786 essential YOR336W 322 - TGCATCGTCTTGTTCTGCAT A|114|P A|114|T D|113|H D|113|N KRE5 Killer toxin REsistant 1365.0 0 1 0 0 0.1007832529138919 P22023 0.2708936929702759 0.5836381316184998 0.1233815848827362 0.4653159976005554 52.97446093067924 45.0 1.0 no 14065 chrXV_950157r 34787 essential YOR336W 387 - TTCAAGTAGAACACGTCGTC L|135|F silent|TTG>TTA|L|135 KRE5 Killer toxin REsistant 1365.0 0 0 0 0 1.9676856943780519 P22023 0.17104771733283994 43.73479186872397 45.0 1.0 no 14066 chrXV_950158r 34788 essential YOR336W 388 - TTTCAAGTAGAACACGTCGT L|135|F silent|TTG>TTA|L|135 KRE5 Killer toxin REsistant 1365.0 0 0 0 0 0.42397819022572936 P22023 0.17104771733283994 43.0405688983966 40.0 1.0 no 14067 chrXV_950229 34789 essential YOR336W 456 + CAACCTTACGATGTTGTCAT P|154|A P|154|S P|154|R P|154|L KRE5 Killer toxin REsistant 1365.0 0 0 0 0 -0.3670223185939136 P22023 0.7639874815940857 0.8200975060462952 0.5122080445289612 0.3110634982585907 45.27870631875175 40.0 1.0 no 14068 chrXV_950232r 34790 essential YOR336W 462 - GTACCAATGACAACATCGTA G|160|A G|160|D G|160|R G|160|S KRE5 Killer toxin REsistant 1365.0 0 0 0 0 0.2267427229024198 P22023 0.09443189948797226 0.032905198633670814 0.01140357181429863 0.19313916563987726 42.781861270157606 40.0 1.0 no 14069 chrXV_950265 34791 essential YOR336W 492 + GCGCCGATATTGATCTTGTA P|166|A P|166|S A|165|G A|165|V KRE5 Killer toxin REsistant 1365.0 0 0 0 0 -0.3823380019977566 P22023 0.0 0.0 0.05424510315060616 0.01926541514694691 49.75008143295537 45.0 1.0 no 14070 chrXV_950321 34794 essential YOR336W 548 + ATTCAATAGGAATTTATTTA F|184|L silent|TTC>TTT|F|184 KRE5 Killer toxin REsistant 1365.0 0 0 0 0 -0.06924382385716832 P22023 0.03273207321763038 31.96153856970017 15.0 1.0 no 14071 chrXV_950396r 34796 essential YOR336W 626 - ACTCCACGCTTTTCCCATCA E|215|Q E|215|K E|215|D silent|GAG>GAA|E|215 KRE5 Killer toxin REsistant 1365.0 0 0 0 0 0.7251569579652707 P22023 0.5144515633583069 0.8393283486366272 0.5542889833450317 57.39418223651967 50.0 1.0 no 14072 chrXV_950501 34797 essential YOR336W 728 + TACTGTACCCAAAGAAATAT T|244|S T|244|I KRE5 Killer toxin REsistant 1365.0 0 0 0 0 1.3433109585654126 P22023 0.6679317355155945 0.12396661192178725 37.718149222725174 30.0 1.0 no 14073 chrXV_950508r 34798 essential YOR336W 738 - GCTCCAACCAATATTTCTTT G|252|A G|252|E A|253|P A|253|T KRE5 Killer toxin REsistant 1365.0 0 0 0 0 0.2817435356341124 P22023 0.8136685490608215 1.0 0.27596625685691833 0.5332610011100769 46.61128561393031 35.0 1.0 no 14074 chrXV_950549r 34799 essential YOR336W 779 - ATTCTTCTGGTTCTAGATCA E|266|Q E|266|K E|265|Q E|265|K KRE5 Killer toxin REsistant 1365.0 0 0 0 0 1.0722854262831314 P22023 0.15726473927497864 0.02933364547789097 0.2526634633541107 0.3814077079296112 46.5476872120106 35.0 1.0 no 14075 chrXV_950684 34801 essential YOR336W 911 + AATCTCTAAACAACTGATTA I|305|M silent|ATC>ATT|I|305 S|306|C S|306|F KRE5 Killer toxin REsistant 1365.0 0 0 0 0 -0.6461992749309141 P22023 0.04781082645058632 0.02857478521764278 0.09515777975320816 33.8000141096698 25.0 1.0 no 14076 chrXV_950861r 34805 essential YOR336W 1091 - TCGTAATTTTCAGTAAACTT silent|ACG>ACC|T|370 silent|ACG>ACA|T|370 KRE5 Killer toxin REsistant 1365.0 0 0 0 0 -0.7230801329737123 P22023 36.65491213124306 25.0 1.0 no 14077 chrXV_951059r 34807 essential YOR336W 1289 - TTACTAATTCGTCATATTGC V|436|L V|436|I KRE5 Killer toxin REsistant 1365.0 0 0 0 0 0.2498931537064071 P22023 0.2939344048500061 0.18577207624912265 39.75352679544785 30.0 1.0 no 14078 chrXV_951176r 34808 essential YOR336W 1406 - TCACCTCACTATCTTCTAAA V|475|L V|475|M silent|GTG>GTC|V|475 silent|GTG>GTA|V|475 KRE5 Killer toxin REsistant 1365.0 0 0 0 0 0.14915209907179414 P22023 0.11969657242298125 0.037778884172439575 43.90578270875676 35.0 1.0 no 14079 chrXV_951241r 34809 essential YOR336W 1471 - GACTCTTTGCGGATATCCCT V|497|L V|497|I R|496|T R|496|K KRE5 Killer toxin REsistant 1365.0 0 0 0 0 -0.3362642183264363 P22023 0.06563494354486465 1.0 0.0 0.0 54.26017790348453 50.0 1.0 no 14080 chrXV_951666r 34812 essential YOR336W 1896 - ACCGAATCAGCAAAATAATT silent|TCG>TCC|S|638 silent|TCG>TCA|S|638 V|639|L V|639|I KRE5 Killer toxin REsistant 1365.0 0 0 0 0 0.38900604951183343 P22023 0.3467414975166321 0.3365435302257538 36.63752437226583 30.0 1.0 no 14081 chrXV_951677 34813 essential YOR336W 1904 + TGCTGATTCGGTATATTCTT A|636|G A|636|V KRE5 Killer toxin REsistant 1365.0 0 0 0 0 -0.22856942376253586 P22023 0.12441945821046828 0.28115618228912354 45.526079642041566 35.0 1.0 no 14082 chrXV_951695 34814 essential YOR336W 1922 + TTCGGTCAACAATACTGCAT S|642|W S|642|L silent|GTC>GTG|V|643 silent|GTC>GTT|V|643 KRE5 Killer toxin REsistant 1365.0 0 1 0 0 -0.4402928261654164 P22023 0.1241065114736557 0.5273203849792479 44.31051671751152 40.0 1.0 no 14083 chrXV_951783 34816 essential YOR336W 2010 + ATCACATTAGTGGATGATTT I|671|M silent|ATC>ATT|I|671 T|672|R T|672|I KRE5 Killer toxin REsistant 1365.0 0 0 0 0 0.06354440943274342 P22023 0.016043713316321373 0.007946428842842579 0.008590226992964745 40.7483595726539 30.0 1.0 no 14084 chrXV_951850r 34818 essential YOR336W 2080 - TCTGATCCTAACACCAACAA R|700|T R|700|K R|698|S silent|AGG>AGA|R|698 KRE5 Killer toxin REsistant 1365.0 0 0 0 0 -0.005906361345368372 P22023 0.0 0.0 0.02230651490390301 43.93810742017347 40.0 1.0 no 14085 chrXV_952021 34819 essential YOR336W 2248 + ACCAGTTAGGCCTTCATAAA Q|751|E Q|751|* N|750|K silent|AAC>AAT|N|750 KRE5 Killer toxin REsistant 1365.0 0 0 0 0 -0.7238363609744469 P22023 0.7745298743247986 0.3035413920879364 47.78720354434785 40.0 1.0 no 14086 chrXV_952056r 34822 essential YOR336W 2286 - CCCTTTTGCAATTCAAATAA K|768|N silent|AAG>AAA|K|768 G|769|R G|769|S KRE5 Killer toxin REsistant 1365.0 0 0 0 0 -1.372454930446206 P22023 0.4993448257446289 0.6047824621200562 0.7758056521415709 40.80500873143655 30.0 1.0 no 14087 chrXV_952208 34823 essential YOR336W 2435 + ACTTTTTCCAGGTTTCTCAC L|813|V L|813|F KRE5 Killer toxin REsistant 1365.0 0 0 0 0 0.915103739232512 P22023 1.0 0.09990207105875017 50.1872401717339 40.0 1.0 no 14088 chrXV_952344r 34826 essential YOR336W 2574 - AACTCGCTCAAATCCATTCT E|864|D silent|GAG>GAA|E|864 E|864|Q E|864|K KRE5 Killer toxin REsistant 1365.0 0 0 0 0 -0.8830958865779821 P22023 0.38163676857948303 0.5380467176437378 0.5914325118064879 46.01591320379248 40.0 1.0 no 14089 chrXV_952374r 34827 essential YOR336W 2604 - TCAAACATCGTTAAATTATT E|875|Q E|875|K M|873|I M|873|I KRE5 Killer toxin REsistant 1365.0 0 1 0 0 0.17806988730877826 P22023 0.3603306710720062 0.048178281635046005 1.0 1.0 32.683164341215054 20.0 1.0 no 14090 chrXV_952468 34828 essential YOR336W 2695 + TTTCTCTTGTTGAGCAATTC S|900|C S|900|F L|901|V L|901|F KRE5 Killer toxin REsistant 1365.0 0 0 0 0 1.3000365023932492 P22023 0.006235538050532341 0.003379386849701405 0.0 0.0 44.32402531460668 35.0 1.0 no 14091 chrXV_952527r 34829 essential YOR336W 2757 - ACAATGTTTAATTCCAGTGT V|926|L V|926|I KRE5 Killer toxin REsistant 1365.0 0 0 0 0 0.17267254165464024 P22023 0.4906391501426697 0.38680440187454224 41.893788235437626 30.0 1.0 no 14092 chrXV_952623r 34831 essential YOR336W 2853 - TCCATTTCAATATCTACTTC M|957|I M|957|I D|958|H D|958|N KRE5 Killer toxin REsistant 1365.0 0 0 0 0 0.5229987356003958 P22023 1.0 1.0 0.009239006787538528 0.02738647721707821 41.77087397933588 30.0 1.0 no 14093 chrXV_952719 34832 essential YOR336W 2946 + AGCAAAACAGTCCTTTCAAC S|983|R silent|AGC>AGT|S|983 KRE5 Killer toxin REsistant 1365.0 0 0 0 0 0.011825414505283405 P22023 0.38299706578254705 42.50759810741585 40.0 1.0 no 14094 chrXV_952771 34837 essential YOR336W 2998 + TAGCACTTGTCGATTCTGCA A|1001|G A|1001|V L|1002|V L|1002|F KRE5 Killer toxin REsistant 1365.0 0 0 0 0 0.3110631596566289 P22023 0.04396069794893265 0.030285205692052838 0.0 0.0 50.370378131913974 45.0 1.0 no 14095 chrXV_959447r 34839 essential YOR340C 713 + TACAGGAAGAGTTGTTTCTG T|239|R T|239|I RPA43 RNA Polymerase A 326.0 0 0 0 0 0.10264340469713976 P46669 0.06571086496114731 0.056157488375902176 -0.3752000033855438 0.09690000116825104 -0.746399998664856 1.4210000038146973 42.405264480271846 40.0 0.0 no 14096 chrXV_959531r 34840 essential YOR340C 629 + AAACAGATCTTTGGGCCACT N|211|K silent|AAC>AAT|N|211 RPA43 RNA Polymerase A 326.0 0 1 0 0 -0.0915243734546796 P46669 0.9418471455574036 48.268931974729576 45.0 0.0 no 14097 chrXV_959654 34842 essential YOR340C 509 - CATCTTCTTCCACGTCGTTA D|176|H D|176|N E|175|Q E|175|K RPA43 RNA Polymerase A 326.0 0 0 0 0 0.4686115618222656 P46669 0.3751413822174072 0.5705742835998535 0.037198346108198166 0.035089120268821716 -0.30799999833106995 -0.2396000027656555 51.51458616033893 45.0 0.0 no 14098 chrXV_959736 34844 essential YOR340C 427 - AATCAAAAGACCAATGTGTG L|148|F silent|TTG>TTA|L|148 RPA43 RNA Polymerase A 326.0 0 0 0 0 -0.6409736833528151 P46669 0.0 -0.3352999985218048 0.04439999908208847 0.2239599972963333 36.61353240732575 35.0 0.0 no 14099 chrXV_959746r 34845 essential YOR340C 414 + ATTCAATCCGCCTCACACAT Q|140|E Q|140|* RPA43 RNA Polymerase A 326.0 0 0 0 0 -0.5863952881063833 P46669 0.03398476168513298 0.8569599986076355 -0.11739999800920485 51.04134341341688 45.0 0.0 no 14100 chrXV_959782 34846 essential YOR340C 381 - TCCAAAACATCTCCAACTTG L|133|F silent|TTG>TTA|L|133 E|134|Q E|134|K RPA43 RNA Polymerase A 326.0 0 0 0 0 0.6692311590107505 P46669 0.04069974645972252 0.0 0.0 2.2888801097869877 -0.5423799753189087 -1.2696199417114258 42.683977380623155 40.0 0.0 no 14101 chrXV_959783r 34847 essential YOR340C 377 + GCCACAAGTTGGAGATGTTT P|127|R P|127|L P|127|A P|127|S RPA43 RNA Polymerase A 326.0 0 0 0 0 -1.3847915567766005 P46669 0.0 0.0 0.0 0.0 11.364700317382812 2.4886798858642583 2.584399938583374 3.664139986038208 49.10479625976637 45.0 0.0 no 14102 chrXV_959827 34851 essential YOR340C 336 - TGGCACCAAGTAAATCCAAA C|118|S C|118|Y W|117|C W|117|* RPA43 RNA Polymerase A 326.0 0 0 0 0 0.8695219627272635 P46669 0.026295797899365425 0.018642021343111992 0.0 1.8030600547790527 8.02422046661377 0.7095400094985962 0.9265999794006348 8.729999542236326 1.208799958229065 2.282599925994873 42.94941483620511 40.0 0.0 no 14103 chrXV_959842r 34855 essential YOR340C 318 + ATCACACCCGATACCCCTTT I|107|M silent|ATC>ATT|I|107 T|108|R T|108|I RPA43 RNA Polymerase A 326.0 0 0 0 0 0.3970378055235606 P46669 0.023509711027145386 0.5220221877098083 0.19765597581863406 -0.40827998518943787 -0.6150400042533875 -0.9128000140190125 -0.8628000020980835 56.338317886949994 50.0 0.0 no 14104 chrXV_959992 34856 essential YOR340C 171 - TGCTTCATGACACCTTGCAA K|63|N silent|AAG>AAA|K|63 M|62|I M|62|I RPA43 RNA Polymerase A 326.0 0 0 0 0 -0.6297555068297609 P46669 0.44088014960289 0.015971807762980458 0.015971807762980458 0.8226400017738342 0.49167999625206 0.49167999625206 0.14640000462532046 0.14640000462532046 0.7582799792289734 0.7582799792289734 49.88566577303681 45.0 0.0 no 14105 chrXV_959991 34857 essential YOR340C 172 - CTGCTTCATGACACCTTGCA K|63|N silent|AAG>AAA|K|63 M|62|I M|62|I RPA43 RNA Polymerase A 326.0 0 0 0 0 0.6407094316786213 P46669 0.44088014960289 0.015971807762980458 0.015971807762980458 0.8226400017738342 0.49167999625206 0.49167999625206 0.14640000462532046 0.14640000462532046 0.7582799792289734 0.7582799792289734 53.361558511752605 50.0 0.0 no 14106 chrXV_961040r 34859 essential YOR341W 56 - TTCTAATCTCTTTAGCTGTT R|25|T R|25|K RPA190 RNA Polymerase A 1664.0 0 0 0 0 0.4786201065668161 P10964 0.01979551650583744 0.5358375906944275 0.5076000094413757 1.0887999534606934 44.051117836902456 30.0 1.0 no 14107 chrXV_961116r 34861 essential YOR341W 132 - TCATATAAACCGCCTGATAC D|51|H D|51|N RPA190 RNA Polymerase A 1664.0 0 0 0 0 -0.4599163813567745 P10964 0.0 0.0 43.41594035703417 40.0 1.0 no 14108 chrXV_961166 34863 essential YOR341W 179 + TCTGTGTTCTACTTGTGGTT L|61|V silent|CTG>TTG|L|61 RPA190 RNA Polymerase A 1664.0 0 1 0 0 0.3261975898799717 P10964 0.6054871678352356 50.53436415513693 40.0 1.0 no 14109 chrXV_961307 34865 essential YOR341W 320 + TTTCCGTTTAAAGTCAGTAG F|108|L silent|TTC>TTT|F|108 R|109|G R|109|C RPA190 RNA Polymerase A 1664.0 0 1 0 0 -0.2688223721945027 P10964 0.07508357614278792 0.040028423070907586 0.005529573187232018 42.18225314158809 35.0 1.0 no 14110 chrXV_961389 34867 essential YOR341W 402 + AAACTAGATGAAATAACTTT L|136|V silent|CTA>TTA|L|136 RPA190 RNA Polymerase A 1664.0 0 0 0 0 0.2599177142108535 P10964 1.0 29.619344597423773 20.0 1.0 no 14111 chrXV_961561r 34869 essential YOR341W 577 - GTCTGACAAAGCTTTAGCGA D|199|H D|199|N L|197|F silent|TTG>TTA|L|197 RPA190 RNA Polymerase A 1664.0 0 0 0 0 0.7288390271902284 P10964 0.11191179603338243 0.5359652042388916 0.05279457196593285 46.10321623039084 45.0 1.0 no 14112 chrXV_961656 34872 essential YOR341W 669 + CACAAAAAACTATTATCTAG H|224|Q silent|CAC>CAT|H|224 RPA190 RNA Polymerase A 1664.0 0 0 0 0 0.975102485017986 P10964 0.1506926566362381 29.958596544577688 25.0 1.0 no 14113 chrXV_961707r 34874 essential YOR341W 723 - AAACCATCCTTTCTAAATTT G|247|A G|247|D G|247|R G|247|S RPA190 RNA Polymerase A 1664.0 0 1 0 0 0.2991484973556389 P10964 0.10570716112852097 0.007329702842980623 0.005480810534209013 0.0241426695138216 39.14392892107236 25.0 1.0 no 14114 chrXV_962013r 34880 essential YOR341W 1029 - ACCAATTTTCTTGATAAATT L|349|F silent|TTG>TTA|L|349 V|350|L V|350|I RPA190 RNA Polymerase A 1664.0 0 0 0 0 -0.032986907511251856 P10964 0.7141287326812744 0.34567931294441223 0.6477030515670776 35.60310454647521 20.0 1.0 no 14115 chrXV_962094r 34882 essential YOR341W 1110 - ACTTCTTCACCAAGCTTGGA V|377|L V|377|I E|376|Q E|376|K RPA190 RNA Polymerase A 1664.0 0 0 0 0 -0.5908469693646731 P10964 0.6626668572425842 0.7070675492286682 0.7252511382102966 0.9050429463386536 50.67550125972008 45.0 1.0 no 14116 chrXV_962129 34883 essential YOR341W 1142 + TCAAAACCAATTGTTGTCCA Q|382|E Q|382|* N|383|K silent|AAC>AAT|N|383 RPA190 RNA Polymerase A 1664.0 0 0 0 0 -2.2860126890047336 P10964 0.03296282514929772 0.011522590182721615 42.86699529764599 35.0 1.0 yes 14117 chrXV_962298 34885 essential YOR341W 1311 + ATCGACTCTACCAAAGCACA I|438|M silent|ATC>ATT|I|438 D|439|E silent|GAC>GAT|D|439 RPA190 RNA Polymerase A 1664.0 0 0 0 0 0.1756519051310586 P10964 0.3076344728469849 0.0 46.383680848696315 45.0 1.0 no 14118 chrXV_962263r 34887 essential YOR341W 1279 - GTCATTTTGAATAGTAACAA D|433|H D|433|N RPA190 RNA Polymerase A 1664.0 0 0 0 0 -0.03549989151671007 P10964 0.0776362344622612 0.39616212248802185 34.82314740170858 25.0 1.0 no 14119 chrXV_962340r 34888 essential YOR341W 1356 - GCTTGTTTAACACCAGGAAT A|459|P A|459|T RPA190 RNA Polymerase A 1664.0 0 0 0 0 0.1711889079442454 P10964 0.029303388670086864 0.08766576647758484 45.40248134545783 40.0 1.0 no 14120 chrXV_962346r 34889 essential YOR341W 1362 - TCCAGTGCTTGTTTAACACC silent|CTG>CTC|L|460 silent|CTG>CTA|L|460 E|461|Q E|461|K RPA190 RNA Polymerase A 1664.0 0 0 0 0 0.7830218295920052 P10964 0.0 0.0 50.79345582448491 45.0 1.0 no 14121 chrXV_962447r 34890 essential YOR341W 1463 - TTTCATTAGTTTCGATATTT E|494|Q E|494|K RPA190 RNA Polymerase A 1664.0 0 0 0 0 0.8177287211087141 P10964 0.0 0.0 37.99444274679968 20.0 1.0 no 14122 chrXV_962501 34891 essential YOR341W 1514 + GACTTATCCAGAACCAGTAA T|506|S T|506|I RPA190 RNA Polymerase A 1664.0 0 0 0 0 -0.029663252454628475 P10964 0.0 0.0 44.413452419112 40.0 1.0 no 14123 chrXV_962541 34893 essential YOR341W 1554 + TTGCGTCAAGCTGTTATTAA R|520|G R|520|C Q|521|E Q|521|* RPA190 RNA Polymerase A 1664.0 0 0 0 0 -0.1604424734499086 P10964 0.01575889252126217 0.002694703405722976 0.23696884512901306 43.611251163312495 35.0 1.0 no 14124 chrXV_962577r 34895 essential YOR341W 1593 - TTCTGTATTTGAGTGGCACC Q|537|H silent|CAG>CAA|Q|537 RPA190 RNA Polymerase A 1664.0 0 0 0 0 -0.8172685730574665 P10964 0.0176126267760992 50.56680123091696 45.0 1.0 no 14125 chrXV_962584r 34896 essential YOR341W 1600 - ATCTTCGTTCTGTATTTGAG D|540|H D|540|N E|539|Q E|539|K RPA190 RNA Polymerase A 1664.0 0 0 0 0 0.024754413463836892 P10964 0.008860006928443909 0.03827611356973648 0.013335763476788998 0.010340307839214802 43.78099884851935 35.0 1.0 no 14126 chrXV_962720r 34898 essential YOR341W 1736 - CATCTCTGTTCTTGATGTGA D|585|H D|585|N R|584|T R|584|K RPA190 RNA Polymerase A 1664.0 0 0 0 0 -1.3943135273817902 P10964 0.0 0.0 0.018289042636752132 0.11997750401496887 1.2261999845504759 1.0637999773025513 47.112436822283144 40.0 1.0 no 14127 chrXV_962769 34901 essential YOR341W 1782 + TTACATAAAGCCTCCATGAT H|596|D H|596|Y RPA190 RNA Polymerase A 1664.0 0 0 0 0 -1.4311576508667014 P10964 0.0 0.0 43.84799692281928 35.0 1.0 no 14128 chrXV_962782 34903 essential YOR341W 1795 + CCATGATGGGTCACAAAGTT silent|TCC>TCG|S|599 silent|TCC>TCT|S|599 RPA190 RNA Polymerase A 1664.0 0 0 0 0 -1.13169181328339 P10964 46.69373434803368 45.0 1.0 no 14129 chrXV_962782r 34904 essential YOR341W 1798 - CCTAACTTTGTGACCCATCA R|606|T R|606|K V|605|L V|605|I RPA190 RNA Polymerase A 1664.0 0 0 0 0 -1.3798974338696788 P10964 0.008504646830260755 0.4000494778156281 0.025409875437617302 0.03146941214799881 2.1770000457763667 0.4124000072479248 50.780228225316016 45.0 1.0 no 14130 chrXV_962811r 34905 essential YOR341W 1827 - AATCTCAAAGTCTTTTCGTT R|615|T R|615|K L|614|F silent|TTG>TTA|L|614 RPA190 RNA Polymerase A 1664.0 0 0 0 0 0.18865426328547968 P10964 0.00916258804500103 0.047706443816423416 0.012743763625621796 3.565000057220459 1.8361999988555908 40.87693454000839 30.0 1.0 no 14131 chrXV_962853 34906 essential YOR341W 1866 + GCTTATAATGCAGATTTCGA A|623|G A|623|V RPA190 RNA Polymerase A 1664.0 0 1 0 0 1.1681267362018672 P10964 0.019911859184503555 0.01350504904985428 42.5353260202873 35.0 1.0 no 14132 chrXV_962898r 34907 essential YOR341W 1914 - GCTCTAGCATTTTCGTTTTG R|644|T R|644|K A|645|P A|645|T RPA190 RNA Polymerase A 1664.0 0 0 0 0 0.7142589059731816 P10964 0.009520511142909529 0.20314130187034607 0.021069245412945747 0.031508814543485635 2.7434000968933105 0.8550000190734863 7.616000175476074 3.251800060272217 48.47580333793599 40.0 1.0 no 14133 chrXV_962979r 34908 essential YOR341W 1995 - TCTTGAATCAAACCTCTAAC D|672|H D|672|N RPA190 RNA Polymerase A 1664.0 0 0 0 0 -1.6695578847730113 P10964 0.0 0.0 38.84878328814278 35.0 1.0 no 14134 chrXV_962994 34909 essential YOR341W 2007 + ATTCAAGATCATATTTCTGC Q|671|E Q|671|* RPA190 RNA Polymerase A 1664.0 0 0 0 0 0.3686866983453191 P10964 0.0 -0.2791999876499176 40.05069285972705 30.0 1.0 no 14135 chrXV_963001 34910 essential YOR341W 2014 + ATCATATTTCTGCGGGTGTT H|673|D H|673|Y RPA190 RNA Polymerase A 1664.0 0 0 0 0 -0.7979070398795765 P10964 0.022064588963985443 0.00339339766651392 49.45400611151052 40.0 1.0 no 14136 chrXV_963074 34911 essential YOR341W 2087 + TTACGGTTGCATCCGTCCTG Y|697|* silent|TAC>TAT|Y|697 RPA190 RNA Polymerase A 1664.0 0 0 0 0 -0.39641345588505295 P10964 55.56747119161162 55.00000000000001 1.0 no 14137 chrXV_963142 34912 essential YOR341W 2155 + TCTTCAAGCCATATCCATTA I|719|M silent|ATC>ATT|I|719 F|720|L silent|TTC>TTT|F|720 RPA190 RNA Polymerase A 1664.0 0 0 0 0 0.1630851164109354 P10964 0.005393195431679486 1.0 1.5994000434875488 0.20319999754428866 47.21634261200131 35.0 1.0 no 14138 chrXV_963147 34913 essential YOR341W 2160 + AAGCCATATCCATTATGGAC P|722|A P|722|S P|722|R P|722|L RPA190 RNA Polymerase A 1664.0 0 0 0 0 0.02300519888408381 P10964 0.0 0.0 0.0 0.0 3.4270000457763667 3.350600004196167 2.6203999519348145 3.077800035476685 45.858576729520685 40.0 1.0 no 14139 chrXV_963285 34916 essential YOR341W 2298 + AACGAAGTTCTCTTCAAAGA N|767|K silent|AAC>AAT|N|767 RPA190 RNA Polymerase A 1664.0 0 0 0 0 -0.2306802532982519 P10964 0.3152581751346588 38.584357379474675 35.0 1.0 no 14140 chrXV_963392r 34917 essential YOR341W 2408 - AGACTTTAGCAGCGACTTCT V|809|L V|809|I RPA190 RNA Polymerase A 1664.0 0 0 0 0 -1.5167735704911864 P10964 1.0 0.042532846331596375 49.401341931179964 45.0 1.0 no 14141 chrXV_963405 34918 essential YOR341W 2418 + GCTAAAGTCTTATCCGTCTT A|807|G A|807|V RPA190 RNA Polymerase A 1664.0 0 0 0 0 0.28751068709291683 P10964 1.0 0.00543434452265501 47.89646875623743 40.0 1.0 no 14142 chrXV_963450 34919 essential YOR341W 2463 + ACTGCCACGGCATTCACTTG T|822|S T|822|I A|823|G A|823|V RPA190 RNA Polymerase A 1664.0 0 0 0 0 0.7180509319906141 P10964 0.03684234991669655 0.0217084176838398 0.2838315665721893 0.35826125741004944 -0.12620000541210175 0.050200000405311584 54.054382558431996 55.00000000000001 1.0 no 14143 chrXV_963749 34924 essential YOR341W 2762 + ATGCAATTCTATGCAAGCTA C|922|W silent|TGC>TGT|C|922 RPA190 RNA Polymerase A 1664.0 0 0 0 0 -0.3791728882164024 P10964 0.20701785385608676 -0.7910000085830688 43.58832773429997 35.0 1.0 no 14144 chrXV_963759 34925 essential YOR341W 2772 + ATGCAAGCTATGGCACTTTC Q|926|E Q|926|* RPA190 RNA Polymerase A 1664.0 0 0 0 0 0.3398333411617409 P10964 0.0 48.85702988456438 45.0 1.0 no 14145 chrXV_963806 34926 essential YOR341W 2819 + TTCTCAAATTATGTGTTTGT S|941|C S|941|F Q|942|E Q|942|* RPA190 RNA Polymerase A 1664.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.14795097146196626 P10964 0.00792184192687273 0.0054423725232481965 0.020609550178051 0.24660000205039975 3.3907999992370605 0.8840000033378601 39.07722097562754 25.0 1.0 no 14146 chrXV_963977r 34931 essential YOR341W 2993 - CTTCACGACCAGCCATACAA E|1004|Q E|1004|K R|1003|P R|1003|H RPA190 RNA Polymerase A 1664.0 0 0 0 0 -5.6186667497620215 P10964 0.0 0.0 0.0 0.0 -1.25 -1.7325999736785889 50.16370613689425 50.0 1.0 yes 14147 chrXV_964015r 34932 essential YOR341W 3031 - ACCGGATCTAGATGTTTTAA G|1017|R G|1017|S G|1017|A G|1017|D RPA190 RNA Polymerase A 1664.0 0 0 0 0 -6.8631162731590045 P10964 0.0 0.0 0.0 0.0 43.130697489009655 35.0 1.0 yes 14148 chrXV_964050 34934 essential YOR341W 3063 + TGTCTAACAAAACAATTAGA L|1023|V silent|CTA>TTA|L|1023 RPA190 RNA Polymerase A 1664.0 0 0 0 0 -0.17936639553821976 P10964 0.0 31.981193271802912 25.0 1.0 no 14149 chrXV_964116 34936 essential YOR341W 3129 + ACGTTAGTGCAATTCATGTA T|1044|R T|1044|M RPA190 RNA Polymerase A 1664.0 0 0 0 0 -0.1317411919986999 P10964 0.009017243981361391 0.0054456270299851894 0.3564000129699707 -1.6253999471664429 43.656959091515425 35.0 1.0 no 14150 chrXV_964390r 34940 essential YOR341W 3406 - ATCTTGGAAGTTCTCAGAAA D|1142|H D|1142|N RPA190 RNA Polymerase A 1664.0 0 0 0 0 0.3444405748746461 P10964 0.07313056290149689 0.377217710018158 40.47072813004309 35.0 1.0 no 14151 chrXV_964509 34941 essential YOR341W 3522 + ATGCGTTCTCTAATTAATCC R|1176|G R|1176|C RPA190 RNA Polymerase A 1664.0 0 0 0 0 0.6973134879144852 P10964 0.01543266698718071 0.002077939687296748 3.691400051116944 3.101599931716919 43.43976752366347 35.0 1.0 no 14152 chrXV_964572r 34942 essential YOR341W 3588 - TTCAATGTCATCTGTGTTGA L|1202|F silent|TTG>TTA|L|1202 RPA190 RNA Polymerase A 1664.0 0 0 0 0 0.7013965511426306 P10964 0.0 -0.7512000203132629 44.35742271054993 35.0 1.0 no 14153 chrXV_964596 34944 essential YOR341W 3609 + ACCTTCCACTTTGCTGGTCA silent|ACC>ACG|T|1204 silent|ACC>ACT|T|1204 T|1204|S T|1204|I RPA190 RNA Polymerase A 1664.0 0 0 0 0 -0.016701640755239888 P10964 0.0 0.0 -0.32659998536109924 -0.6679999828338623 57.609854957134935 50.0 1.0 no 14154 chrXV_964597r 34945 essential YOR341W 3613 - ACCGTGACCAGCAAAGTGGA G|1211|R G|1211|S G|1211|A G|1211|D RPA190 RNA Polymerase A 1664.0 0 0 0 0 -3.9566834332292222 P10964 0.0 0.0 0.0 0.0 51.71011710010561 55.00000000000001 1.0 yes 14155 chrXV_964693 34946 essential YOR341W 3706 + CGCAAATGACTTTGCCTATC Q|1237|E Q|1237|* RPA190 RNA Polymerase A 1664.0 0 0 0 0 0.6977576004842947 P10964 0.6534640192985535 45.992328709499084 45.0 1.0 no 14156 chrXV_964707r 34948 essential YOR341W 3723 - TCAGAAACATCATTCCAGAT D|1248|H D|1248|N RPA190 RNA Polymerase A 1664.0 0 0 0 0 -1.1673723918495302 P10964 0.09981033205986024 0.5506662130355835 41.533836103326394 35.0 1.0 no 14157 chrXV_999042 34949 essential YOR353C 1767 - GTCATAACCGGATGCTGTTT M|595|I M|595|I SOG2 791.0 0 0 0 0 1.3136062698099271 Q08817 0.9553959965705872 0.9553959965705872 0.2295864820480347 0.2295864820480347 49.50243989925075 45.0 0.0 no 14158 chrXV_999128r 34952 essential YOR353C 1678 + CTACTAGCGATACTATTCCA T|561|S T|561|I SOG2 791.0 0 0 0 0 0.7246474182301494 Q08817 0.9491789937019348 0.9472420215606691 0.8060475587844849 0.2577980756759644 45.88922598822786 40.0 0.0 no 14159 chrXV_999276r 34955 essential YOR353C 1530 + TCAAATAGTAATATTCTGAC S|511|* S|511|L SOG2 791.0 0 0 0 0 -0.3081344370287757 Q08817 0.9298099875450134 0.1741652637720108 32.73186563406472 25.0 0.0 no 14160 chrXV_999372 34959 essential YOR353C 1437 - GTACTGGTCGTACTTGCTGC S|485|T S|485|N SOG2 791.0 0 0 0 0 0.4413530770686899 Q08817 0.9512869715690612 0.9536849856376648 0.5919259190559387 0.5259045362472534 54.86022543869808 55.00000000000001 0.0 no 14161 chrXV_999398 34960 essential YOR353C 1411 - TCCACCGCTTGTGATACTAC G|477|R G|477|R G|477|A G|477|E SOG2 791.0 0 0 0 0 -0.21590373162082602 Q08817 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.5756703615188599 0.5756703615188599 0.8306449651718141 1.0 51.756153243216716 50.0 0.0 no 14162 chrXV_999399r 34961 essential YOR353C 1407 + TCCAGTAGTATCACAAGCGG silent|TCC>TCG|S|470 silent|TCC>TCT|S|470 S|470|C S|470|F SOG2 791.0 0 0 0 1 -0.09938996002596502 Q08817 0.945252001285553 0.9294660091400146 0.10222336649894714 0.3011106252670288 49.344539331274966 50.0 0.0 no 14163 chrXV_999434r 34964 essential YOR353C 1372 + CCAAGAAACATTCTTTTTCG silent|CCC>CCG|P|458 silent|CCC>CCT|P|458 SOG2 791.0 0 0 0 0 0.01010084615710097 Q08817 39.60679576503179 35.0 0.0 no 14164 chrXV_999712r 34967 essential YOR353C 1094 + ATCACATACTGATAATCTGG S|366|* S|366|L H|367|D H|367|Y SOG2 791.0 0 0 0 0 -0.5323912913965512 Q08817 0.9298099875450134 0.9473130106925964 0.9489949941635132 0.0 0.041643917560577386 0.00594327924773097 39.33493609932742 35.0 0.0 no 14165 chrXV_999830 34968 essential YOR353C 979 - ACTAAATAGGAGCTTCCGAC S|333|T S|333|N SOG2 791.0 0 0 0 0 1.012454154605284 Q08817 0.9512869715690612 0.9536849856376648 0.3519498407840729 0.036724068224430084 44.51850919711217 45.0 0.0 no 14166 chrXV_999979r 34970 essential YOR353C 827 + TGCAGAATCAGAACAAAGTG A|277|G A|277|V SOG2 791.0 0 0 0 0 0.9474384362654262 Q08817 0.9484469890594482 0.9504740238189696 0.3380740284919739 0.34200477600097656 37.660626493806255 40.0 0.0 no 14167 chrXV_1000011r 34973 essential YOR353C 795 + ACCTCTGCAACATCTTTCAG silent|ACC>ACG|T|266 silent|ACC>ACT|T|266 T|266|S T|266|I SOG2 791.0 0 0 0 0 -0.21155789403686606 Q08817 0.9491789937019348 0.9472420215606691 0.4003438055515289 0.08335693925619125 49.098139880715046 45.0 0.0 no 14168 chrXV_1000158 34976 essential YOR353C 651 - TTCGCTGCTCTAGATATTTT silent|GCG>GCC|A|223 silent|GCG>GCA|A|223 A|223|P A|223|T SOG2 791.0 0 0 0 0 0.21278199942668494 Q08817 0.9573720097541808 0.9523990154266356 0.16464295983314514 0.14393292367458346 46.44720296334498 35.0 0.0 no 14169 chrXV_1000164 34977 essential YOR353C 645 - GCTCTAGATATTTTAGGTTC R|221|T R|221|K A|222|P A|222|T SOG2 791.0 0 0 0 0 -0.13176176665369455 Q08817 0.932735025882721 0.955805003643036 0.9573720097541808 0.9523990154266356 0.05158878490328789 0.6508123278617859 0.03769687935709953 0.07450250536203384 44.059320193193464 35.0 0.0 no 14170 chrXV_1000283 34978 essential YOR353C 526 - TACTTGGTCAAGCTCTTCTT V|182|L V|182|I SOG2 791.0 0 0 0 0 1.0390396218196871 Q08817 0.9539830088615416 0.9574310183525084 0.2257542908191681 0.3018381595611572 48.88430784373247 40.0 0.0 no 14171 chrXV_1000284 34979 essential YOR353C 525 - ACTTGGTCAAGCTCTTCTTT V|182|L V|182|I SOG2 791.0 0 0 0 0 1.0017460785883658 Q08817 0.9539830088615416 0.9574310183525084 0.2257542908191681 0.3018381595611572 49.77902984632669 40.0 0.0 no 14172 chrXV_1000318r 34980 essential YOR353C 488 + GCTGAGCATCTTGGATTTAG L|164|V silent|CTG>TTG|L|164 S|165|R silent|AGC>AGT|S|165 SOG2 791.0 0 0 0 0 0.4822263303322454 Q08817 0.9512209892272948 0.9417110085487366 0.023482671007514 0.7019469738006592 47.785817129914 45.0 0.0 no 14173 chrXV_1000445 34981 essential YOR353C 364 - TGGCAATGCTTCAATCTCAT L|127|F silent|TTG>TTA|L|127 SOG2 791.0 0 0 0 0 0.4933981509379466 Q08817 0.9587849974632264 0.021098874509334564 46.643030604485894 40.0 0.0 no 14174 chrXV_1000474 34982 essential YOR353C 335 - GATCCAAGATCTCTAATTGA D|118|H D|118|N L|117|F silent|TTG>TTA|L|117 SOG2 791.0 0 0 0 0 1.0437585465796226 Q08817 0.9486550092697144 0.956179976463318 0.9587849974632264 0.009142272174358368 0.11837144196033478 0.021132867783308033 41.33339340282288 35.0 0.0 no 14175 chrXV_1000477r 34983 essential YOR353C 329 + ATGCCCTCAATTAGAGATCT C|111|W silent|TGC>TGT|C|111 P|112|A P|112|S SOG2 791.0 0 0 0 0 0.5439226417703324 Q08817 0.9286419749259948 0.9562489986419678 0.9498909711837769 0.0 0.3810200989246368 0.2180813103914261 48.19139244052724 40.0 0.0 no 14176 chrXV_1000568 34985 essential YOR353C 241 - CCTCTTGAAACTCGCTGGTA K|86|N silent|AAG>AAA|K|86 R|87|T R|87|K SOG2 791.0 0 0 0 0 -0.5820101535035204 Q08817 0.9355990290641784 0.932735025882721 0.955805003643036 0.5360653996467589 0.5490753650665283 1.0 50.209505975572135 50.0 0.0 no 14177 chrXV_1015965 34990 essential YOR361C 1668 - ACAACCACAAATCTACCCGC V|563|L V|563|I V|562|L V|562|I PRT1 PRoTein synthesis 763.0 0 0 0 0 0.37243675972534857 P06103 0.9539830088615416 0.9574310183525084 0.9539830088615416 0.9574310183525084 0.4773591458797455 0.40848833322525024 0.1098662167787552 0.3300323188304901 2.354640007019043 0.28496000170707697 -0.5667200088500977 -0.323419988155365 48.458909568765364 50.0 0.0 no 14178 chrXV_1016039r 34994 essential YOR361C 1591 + AGACTGACGTAATTAAAAGA T|532|S T|532|I PRT1 PRoTein synthesis 763.0 0 0 0 0 -0.30737203287488096 P06103 0.9491789937019348 0.9472420215606691 0.830048143863678 0.35699671506881714 33.590419618267624 30.0 0.0 no 14179 chrXV_1016196 34995 essential YOR361C 1437 - TTCAATTCAACCTTTTCAAC L|485|F silent|TTG>TTA|L|485 PRT1 PRoTein synthesis 763.0 0 1 0 0 0.4836453381243306 P06103 0.9587849974632264 0.04747837781906128 0.9513000249862672 39.595862065591405 30.0 0.0 no 14180 chrXV_1016237r 34996 essential YOR361C 1393 + TCAGTAATCTACAAATTTGT F|465|L silent|TTC>TTT|F|465 PRT1 PRoTein synthesis 763.0 0 0 0 0 0.4064714631283168 P06103 0.9387490153312684 0.11986073106527327 0.9773799777030944 36.00971885520005 25.0 0.0 no 14181 chrXV_1016324r 35000 essential YOR361C 1306 + TCTCCAACGTAACTCTGCAC S|437|C S|437|F silent|GTC>GTG|V|436 silent|GTC>GTT|V|436 PRT1 PRoTein synthesis 763.0 0 0 0 0 0.024684624462691408 P06103 0.945252001285553 0.9294660091400146 0.022786367684602737 0.01861895248293877 0.07971999794244766 -0.33621999621391296 49.1138736291167 50.0 0.0 no 14182 chrXV_1016379r 35001 essential YOR361C 1251 + ACCATTGCTGAAGTTCCTCG silent|ACC>ACG|T|418 silent|ACC>ACT|T|418 T|418|S T|418|I PRT1 PRoTein synthesis 763.0 0 0 0 0 -1.3485867167954366 P06103 0.9491789937019348 0.9472420215606691 0.918319821357727 0.03255066648125648 1.2549400329589844 -2.155780076980591 51.723109487083825 50.0 0.0 no 14183 chrXV_1016435r 35002 essential YOR361C 1195 + CTTCTGTTTTATTGGCTTAT S|400|C S|400|F PRT1 PRoTein synthesis 763.0 0 0 0 0 0.03163721319276476 P06103 0.945252001285553 0.9294660091400146 0.043748829513788216 0.04992929473519325 0.4729599952697754 -1.0286200046539309 44.68449061538058 30.0 0.0 no 14184 chrXV_1016443r 35003 essential YOR361C 1187 + TGACGAGCCTTCTGTTTTAT D|397|E silent|GAC>GAT|D|397 PRT1 PRoTein synthesis 763.0 0 0 0 0 -0.0013365537468628882 P06103 0.9532920122146606 1.0 0.12347999960184095 48.537832619749175 40.0 0.0 no 14185 chrXV_1016457 35004 essential YOR361C 1176 - GGCTCGTCACCGTTTCTGAA E|398|D silent|GAG>GAA|E|398 E|398|Q E|398|K PRT1 PRoTein synthesis 763.0 0 0 0 0 -0.6962384925157108 P06103 0.94931298494339 0.956179976463318 0.9475290179252625 0.571902334690094 0.569857656955719 0.8648301959037781 0.2611599862575531 -0.24262000620365146 -0.3595399856567383 54.975060377936366 55.00000000000001 0.0 no 14186 chrXV_1016532 35006 essential YOR361C 1101 - TTCAAAGCCTTAGCTTCTAA L|373|F silent|TTG>TTA|L|373 PRT1 PRoTein synthesis 763.0 0 0 0 0 0.9310519217248284 P06103 0.9587849974632264 0.013610648922622204 11.530500411987305 44.347602512412436 35.0 0.0 no 14187 chrXV_1016637 35007 essential YOR361C 996 - ACTAAAGGCCATTTCAGATA V|339|L V|339|I PRT1 PRoTein synthesis 763.0 0 1 0 0 0.6240297477292096 P06103 0.9539830088615416 0.9574310183525084 1.0 0.7723836898803711 -1.1297199726104736 -1.3648200035095217 42.73753291920485 35.0 0.0 no 14188 chrXV_1016768 35010 essential YOR361C 865 - TTCTACAATGATTGGTTCCG E|295|Q E|295|K V|294|L V|294|I PRT1 PRoTein synthesis 763.0 0 0 0 0 0.6789994416956416 P06103 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.05130089446902275 0.06256625801324844 0.6309270858764648 0.5724435448646545 0.4716399908065796 0.7107399702072144 0.23921999335289 0.10886000096797943 44.66479765442261 40.0 0.0 no 14189 chrXV_1016785r 35012 essential YOR361C 845 + GTACCTGGTCACTTTCTCCA Y|283|* silent|TAC>TAT|Y|283 L|284|V silent|CTG>TTG|L|284 PRT1 PRoTein synthesis 763.0 0 0 0 0 -0.03846473111716103 P06103 0.9512209892272948 0.027631299570202827 2.765660047531128 57.03346803558172 50.0 0.0 no 14190 chrXV_1016804 35014 essential YOR361C 829 - GTACTTTTCATTCGGAGAGA K|282|N silent|AAG>AAA|K|282 PRT1 PRoTein synthesis 763.0 0 0 0 0 0.6768754842033079 P06103 0.9355990290641784 0.346671462059021 -0.14688000082969666 45.1874707155805 40.0 0.0 no 14191 chrXV_1016884r 35018 essential YOR361C 746 + TCAACAGGGTGTAACTGCAT Q|250|E Q|250|* Q|251|E Q|251|* PRT1 PRoTein synthesis 763.0 0 0 0 0 -1.5248624940440119 P06103 0.9590039849281312 0.9590039849281312 0.9803557991981506 0.12582258880138394 -0.5499600172042847 -0.4667200148105621 46.81544913000704 45.0 0.0 no 14192 chrXV_1016887 35019 essential YOR361C 746 - ATGCAGTTACACCCTGTTGA A|255|P A|255|T PRT1 PRoTein synthesis 763.0 0 0 0 0 0.13079447565289082 P06103 0.9573720097541808 0.9523990154266356 0.061075787991285324 0.14261148869991302 3.8335399627685542 2.5415000915527344 52.27543127888129 45.0 0.0 no 14193 chrXV_1016915 35020 essential YOR361C 718 - AAACAAATAGGTACCCTTTG L|245|F silent|TTG>TTA|L|245 PRT1 PRoTein synthesis 763.0 0 0 0 0 0.3474086646149465 P06103 0.9587849974632264 0.08101750910282135 1.855280041694641 39.737395122067426 35.0 0.0 no 14194 chrXV_1017059 35023 essential YOR361C 574 - CACTTTGTCGTCCATTAACC V|198|L V|198|M PRT1 PRoTein synthesis 763.0 0 1 0 0 1.5100462958781382 P06103 0.9539830088615416 0.9587630033493042 0.05564016103744507 0.02503315918147564 -0.6830199956893921 -0.6943600177764893 49.07572534374401 45.0 0.0 no 14195 chrXV_1017077r 35024 essential YOR361C 553 + CATCTAGTTCCTTAAAATCC S|186|C S|186|F PRT1 PRoTein synthesis 763.0 0 0 0 0 0.6834864508463842 P06103 0.945252001285553 0.9294660091400146 0.006016377359628677 0.012841506861150265 0.05183999985456467 -0.11748000234365465 42.292446626131664 35.0 0.0 no 14196 chrXV_1017125r 35026 essential YOR361C 505 + ACGACTTTGACACCGAATTC D|169|E silent|GAC>GAT|D|169 D|170|E silent|GAC>GAT|D|170 PRT1 PRoTein synthesis 763.0 0 1 0 0 0.9584683256558032 P06103 0.9532920122146606 0.9532920122146606 1.0 0.4812449514865875 -0.049479998648166656 44.33886627013339 45.0 0.0 no 14197 chrXV_1017124r 35027 essential YOR361C 506 + CGACTTTGACACCGAATTCA D|170|E silent|GAC>GAT|D|170 PRT1 PRoTein synthesis 763.0 0 1 0 0 0.02663500857889584 P06103 0.9532920122146606 0.4812449514865875 45.11745775486105 45.0 0.0 no 14198 chrXV_1017265r 35028 essential YOR361C 365 + GACGAAAGGTTTTCTCTTCG T|123|R T|123|M PRT1 PRoTein synthesis 763.0 0 1 0 0 1.3179156715125306 P06103 0.9476869702339172 0.9502379894256592 0.00878622941672802 0.004591410513967276 8.761099815368652 1.3454200029373171 44.138414279616654 45.0 0.0 no 14199 chrXV_1017291r 35029 essential YOR361C 339 + TTTCCAATTGATGAAGCCAC P|115|A P|115|S P|115|R P|115|L PRT1 PRoTein synthesis 763.0 0 0 0 0 0.8842715564714939 P06103 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.053517356514930725 0.03701063618063927 0.019393306225538254 0.029346255585551262 2.7426600456237797 3.446199893951416 2.46314001083374 2.100860118865967 2.594919919967652 3.10657000541687 2.4410901069641118 2.0429601669311523 44.80930876923247 40.0 0.0 no 14200 chrXV_1017288 35030 essential YOR361C 345 - TTACCAGTGGCTTCATCAAT G|121|A G|121|D G|121|R G|121|S PRT1 PRoTein synthesis 763.0 0 1 0 0 0.21483956786430025 P06103 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.015486042946577072 0.03413031250238418 0.006139745004475118 0.022447101771831512 2.757200002670288 2.506419897079468 2.1340200901031494 2.677020072937012 48.375609471987104 40.0 0.0 no 14201 chrXV_1017316r 35031 essential YOR361C 314 + AGCTGGTAAAGTTGTTAACA A|106|G A|106|V PRT1 PRoTein synthesis 763.0 0 0 0 0 0.5083010517561627 P06103 0.9484469890594482 0.9504740238189696 0.4135430753231049 0.8019524216651917 0.8220000267028809 3.2353200912475586 1.6665999889373782 1.613759994506836 41.3487714433 35.0 0.0 no 14202 chrXV_1017365 35033 essential YOR361C 268 - TTTCAAAACAGGAACTTTGG L|95|F silent|TTG>TTA|L|95 PRT1 PRoTein synthesis 763.0 0 0 0 0 -1.1461406395193623 P06103 0.9587849974632264 0.0971076637506485 2.912300109863281 37.116432646128715 35.0 0.0 no 14203 chrXV_1017445 35036 essential YOR361C 188 - TGACCTTGTATTGTTCTTCC V|69|L V|69|I K|68|N silent|AAG>AAA|K|68 PRT1 PRoTein synthesis 763.0 0 1 0 0 0.4928397064467713 P06103 0.9539830088615416 0.9574310183525084 0.9355990290641784 0.1894301474094391 0.3161798715591431 0.4200676381587982 49.990969174652044 40.0 0.0 no 14204 chrXV_1017405r 35038 essential YOR361C 225 + GATCAGTACATCGTCGTTAA Q|77|E Q|77|* PRT1 PRoTein synthesis 763.0 0 0 0 0 0.4638868578790011 P06103 0.9590039849281312 0.3046858012676239 0.6875399947166443 44.17566530915651 40.0 0.0 no 14205 chrXV_1017463r 35039 essential YOR361C 167 + CGACATTGATTTTTCCGACC D|57|E silent|GAC>GAT|D|57 PRT1 PRoTein synthesis 763.0 0 1 0 0 0.649565175183813 P06103 0.9532920122146606 0.6058072447776794 47.2356615131589 45.0 0.0 no 14206 chrXV_1017499r 35040 essential YOR361C 131 + TTTCGAAGACATTAAGCTAG F|45|L silent|TTC>TTT|F|45 PRT1 PRoTein synthesis 763.0 0 0 0 0 -0.3298442158408642 P06103 0.9387490153312684 0.2677976191043854 38.1231459532122 35.0 0.0 no 14207 chrXV_1017551r 35041 essential YOR361C 79 + CTCGCAACACACAGCTCAAA R|28|G R|28|C silent|CGC>CGG|R|28 silent|CGC>CGT|R|28 PRT1 PRoTein synthesis 763.0 0 0 0 0 -1.2102024565314369 P06103 0.8994590044021606 0.8926740288734436 46.59367378519562 50.0 0.0 no 14208 chrXV_1018140r 35043 essential YOR362C 584 + AGCTGCAAAGATTATCTATT A|196|G A|196|V A|197|G A|197|V PRE10 PRoteinase yscE 288.0 0 1 0 0 0.2906097796520803 P21242 0.05922181159257889 0.9939269423484802 0.10888391733169556 0.1911158412694931 1.9601500034332275 1.1054680347442627 2.0149600505828857 3.48388409614563 1.8804999589920044 3.3132998943328857 40.135761169181706 30.0 0.0 no 14209 chrXV_1018175 35044 essential YOR362C 552 - TCTCTTGCTGAAAGACCTTC R|190|T R|190|K E|191|Q E|191|K PRE10 PRoteinase yscE 288.0 0 1 0 0 -0.04430770042233178 P21242 0.3213270604610443 0.4459477961063385 0.2996186912059784 0.0174949262291193 -0.024935999885201454 -0.5108379721641539 0.5181260108947754 0.18832600116729736 47.39057596066556 45.0 0.0 no 14210 chrXV_1018347r 35055 essential YOR362C 377 + CAACAGTGTTAGACCGTTCG N|127|K silent|AAC>AAT|N|127 PRE10 PRoteinase yscE 288.0 0 0 0 0 0.5442564380775206 P21242 0.3631083071231842 0.0341779999434948 -0.003357499837875366 47.27037553679838 50.0 0.0 no 14211 chrXV_1018383 35058 essential YOR362C 344 - CCTGCACATATTGTCCTAAA Q|121|H silent|CAG>CAA|Q|121 silent|GTG>GTC|V|120 silent|GTG>GTA|V|120 PRE10 PRoteinase yscE 288.0 0 0 0 0 -0.3432326841853173 P21242 1.0 -0.10233599692583084 2.1291549205780034 46.76483925625496 40.0 0.0 no 14212 chrXV_1018508r 35065 essential YOR362C 216 + CACATCGGTTGCGTTTATTC H|73|Q silent|CAC>CAT|H|73 I|74|M silent|ATC>ATT|I|74 PRE10 PRoteinase yscE 288.0 0 0 0 0 0.5297609901058978 P21242 0.1684642732143402 0.04477114602923393 0.3235839903354645 0.9089840054512024 48.28963154706304 45.0 0.0 no 14213 chrXV_1018645 35070 essential YOR362C 82 - ACCGTTTTCGACTGCTTTGA G|34|R G|34|S G|34|A G|34|D PRE10 PRoteinase yscE 288.0 0 0 0 0 -1.0720437523603088 P21242 0.059915013611316674 1.0 0.7751824855804443 0.06849920749664308 10.687893867492676 3.159409999847412 2.473599910736084 11.47202205657959 10.109518051147461 2.891833066940308 1.9299800395965576 9.730264663696287 50.705388937426456 45.0 0.0 no 14214 chrXV_1018676 35072 essential YOR362C 51 - ACTTGGAAATTTCTACCATC V|24|L V|24|I PRE10 PRoteinase yscE 288.0 0 0 0 0 0.715491346069097 P21242 0.014547291211783888 0.1953664124011993 1.2773380279541016 0.3206520080566406 0.4894599914550781 0.29396000504493713 -0.782800018787384 -0.7135999798774719 41.726068135154826 35.0 0.0 no 14215 chrXV_1029775r 35077 essential YOR370C 1197 + GGCAGCGAAATTTGTCCAGA silent|GGC>GGG|G|400 silent|GGC>GGT|G|400 S|401|R silent|AGC>AGT|S|401 MRS6 Mitochondrial RNA Splicing 603.0 0 0 0 0 0.8907979265278134 P32864 0.02669001743197441 49.90094489692496 50.0 0.0 no 14216 chrXV_1029832 35080 essential YOR370C 1143 - TTACCAGATTTCAAAGAGCC G|387|A G|387|D G|387|R G|387|S MRS6 Mitochondrial RNA Splicing 603.0 0 0 0 0 1.5642763731691285 P32864 0.6796392202377319 0.8330380916595459 0.4706361293792725 0.7446219325065613 44.413452419112 40.0 0.0 no 14217 chrXV_1029885 35081 essential YOR370C 1090 - CTCATTGAACCATTCAGTAC E|370|Q E|370|K MRS6 Mitochondrial RNA Splicing 603.0 0 0 0 0 -0.4829765758121642 P32864 0.5029796361923218 0.7766534686088562 43.910556448578575 40.0 0.0 no 14218 chrXV_1029886 35082 essential YOR370C 1089 - TCATTGAACCATTCAGTACA E|370|Q E|370|K MRS6 Mitochondrial RNA Splicing 603.0 0 0 0 0 0.2246404258244995 P32864 0.5029796361923218 0.7766534686088562 43.412237719526956 35.0 0.0 no 14219 chrXV_1029938r 35085 essential YOR370C 1034 + TGTCCCTCAACAACAGTACC silent|GTC>GTG|V|346 silent|GTC>GTT|V|346 P|347|A P|347|S MRS6 Mitochondrial RNA Splicing 603.0 0 0 0 0 0.8932252351448757 P32864 0.7484957575798035 1.0 51.14046354473351 50.0 0.0 no 14220 chrXV_1030002 35086 essential YOR370C 973 - TTTCTCTGAAACTTCAACTT E|330|D silent|GAG>GAA|E|330 E|330|Q E|330|K MRS6 Mitochondrial RNA Splicing 603.0 0 0 0 0 0.6447733494998249 P32864 0.3124977946281433 0.15403108298778534 0.5391097068786621 39.383713344528864 30.0 0.0 no 14221 chrXV_1030013 35087 essential YOR370C 962 - CTTCAACTTTGGATCCATCT E|327|Q E|327|K V|326|L V|326|I MRS6 Mitochondrial RNA Splicing 603.0 0 0 0 0 -0.20959209288652805 P32864 0.597769558429718 0.969054877758026 0.5208213925361633 0.7139903903007507 47.42593982096172 40.0 0.0 no 14222 chrXV_1030043r 35088 essential YOR370C 929 + CTTCAACCCTACAACTAAAG F|311|L silent|TTC>TTT|F|311 N|312|K silent|AAC>AAT|N|312 MRS6 Mitochondrial RNA Splicing 603.0 0 0 0 0 -0.01396165295901533 P32864 0.6486207246780396 0.14663627743721008 40.85449416856608 40.0 0.0 no 14223 chrXV_1030137 35091 essential YOR370C 838 - TTCTCCTGGCCCACCATACT E|286|Q E|286|K G|285|A G|285|E MRS6 Mitochondrial RNA Splicing 603.0 0 0 0 0 -1.095782338047195 P32864 0.0 0.0 0.5487071275711061 0.0301834587007761 0.25599998235702515 0.6534000635147095 60.88344438505681 55.00000000000001 0.0 no 14224 chrXV_1030150 35094 essential YOR370C 825 - CCATACTTGGAGCATAGTGC G|282|R G|282|S K|280|N silent|AAG>AAA|K|280 MRS6 Mitochondrial RNA Splicing 603.0 0 0 0 0 -0.5579700765746689 P32864 0.0 0.0 0.20805956423282626 50.821901027229224 50.0 0.0 no 14225 chrXV_1030260r 35095 essential YOR370C 712 + TCGAATTAATCTTCTCAATT F|238|L silent|TTC>TTT|F|238 MRS6 Mitochondrial RNA Splicing 603.0 0 0 0 0 0.6699875627764773 P32864 0.3007330596446991 36.541729227479664 25.0 0.0 no 14226 chrXV_1030373r 35099 essential YOR370C 599 + TATCAAATTCGTACTCAACT I|201|M silent|ATC>ATT|I|201 MRS6 Mitochondrial RNA Splicing 603.0 0 0 0 0 0.7328062723744295 P32864 0.4182345271110535 37.98756205830989 30.0 0.0 no 14227 chrXV_1030409 35100 essential YOR370C 566 - TCCTCTTTGTCATTAGTGGT R|195|T R|195|K R|195|S silent|AGG>AGA|R|195 MRS6 Mitochondrial RNA Splicing 603.0 0 0 0 0 -4.273562312873733 P32864 0.0 0.0 0.0 52.02302159083331 40.0 0.0 yes 14228 chrXV_1030478 35101 essential YOR370C 497 - AACAATCATTTTCATAAGTA C|172|S C|172|Y D|171|H D|171|N MRS6 Mitochondrial RNA Splicing 603.0 0 0 0 0 0.4392633854119625 P32864 0.7603400349617004 0.04881929606199265 0.04519219696521759 0.315101683139801 33.50365335410657 20.0 0.0 no 14229 chrXV_1030410r 35102 essential YOR370C 562 + ACCTACCACTAATGACAAAG L|189|V silent|CTA>TTA|L|189 N|188|K silent|AAC>AAT|N|188 MRS6 Mitochondrial RNA Splicing 603.0 0 0 0 0 0.7426371223503077 P32864 0.2799268066883087 0.7560521364212036 40.945408889953 40.0 0.0 no 14230 chrXV_1030757 35103 essential YOR370C 218 - AATCATTCTTATCAATATGA D|79|H D|79|N MRS6 Mitochondrial RNA Splicing 603.0 0 0 0 0 0.3748471716447483 P32864 0.10848698765039444 0.5595147609710693 3.0706000328063965 1.5945501327514648 34.269765124558376 20.0 0.0 no 14231 chrXV_1030789r 35104 essential YOR370C 183 + GCTGCTGCATTAGCTTGGCA A|62|G A|62|V A|63|G A|63|V MRS6 Mitochondrial RNA Splicing 603.0 0 0 0 0 0.02149004367938984 P32864 0.04466917738318443 0.12414463609457015 0.23698900640010834 0.5163350701332092 58.602319184159406 55.00000000000001 0.0 no 14232 chrXV_1030851 35105 essential YOR370C 124 - ATCAACTTTATCTGGTGTAG D|48|H D|48|N V|47|L V|47|I MRS6 Mitochondrial RNA Splicing 603.0 0 0 0 0 -0.08753103316880118 P32864 0.0 0.0 0.4740067720413208 0.26790502667427063 41.81249267503858 35.0 0.0 no 14233 chrXV_1030875 35108 essential YOR370C 100 - TGGCAAAGGGTCTTCAATAC L|39|F silent|TTG>TTA|L|39 MRS6 Mitochondrial RNA Splicing 603.0 0 0 0 0 -0.4536684821537257 P32864 44.647849501922856 45.0 0.0 no 14234 chrXV_1035204r 35114 essential YOR372C 1245 + TCTTTGCATAGTACAACCAC S|416|C S|416|F H|418|D H|418|Y 0 0 0 0 0.6042843435147623 Q08887 0.945252001285553 0.9294660091400146 0.9473130106925964 0.9489949941635132 0.06865761429071426 0.10122992098331453 0.20034320652484894 0.03374810516834259 45.28060533387537 40.0 0.0 no 14235 chrXV_1035275 35115 essential YOR372C 1177 - AAACAATTGGTCATCCACAT L|398|F silent|TTG>TTA|L|398 0 0 0 0 0.4305612561584673 Q08887 0.9587849974632264 0.024323556572198868 41.946155270523256 35.0 0.0 no 14236 chrXV_1035311 35118 essential YOR372C 1141 - ATCTGATCTCGAAGCTAACA D|387|H D|387|N 0 0 0 0 0.10519939890643362 Q08887 0.9486550092697144 0.956179976463318 0.15501746535301208 0.4683520495891571 43.18152579002083 40.0 0.0 no 14237 chrXV_1035312 35119 essential YOR372C 1140 - TCTGATCTCGAAGCTAACAA D|387|H D|387|N R|385|T R|385|K 0 0 0 0 1.2997703492796755 Q08887 0.9486550092697144 0.956179976463318 0.932735025882721 0.955805003643036 0.15501746535301208 0.4683520495891571 0.5633782148361206 1.0 41.769547727039644 40.0 0.0 no 14238 chrXV_1035436r 35120 essential YOR372C 1013 + TAGCACTAGCACACTAACTA S|339|R silent|AGC>AGT|S|339 T|340|S T|340|I 0 0 0 0 0.1876876102326112 Q08887 0.9417110085487366 0.9491789937019348 0.9472420215606691 0.5110489130020142 0.8237998485565186 0.212150439620018 44.10344840869993 40.0 0.0 no 14239 chrXV_1035548 35123 essential YOR372C 904 - CCCTATGGATGTTGCATTAG G|308|R G|308|R G|308|A G|308|E 0 1 0 0 -0.3745720683562392 Q08887 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.5569039583206177 0.5569039583206177 0.7750225663185121 1.0 49.24503135516119 45.0 0.0 no 14240 chrXV_1035548r 35124 essential YOR372C 901 + CCACTAATGCAACATCCATA T|302|S T|302|I silent|ACC>ACG|T|301 silent|ACC>ACT|T|301 0 0 0 0 -0.3511728068132978 Q08887 0.9491789937019348 0.9472420215606691 0.5348608493804932 0.14632324874401093 45.2840764259268 40.0 0.0 no 14241 chrXV_1035549r 35125 essential YOR372C 900 + ACCACTAATGCAACATCCAT silent|ACC>ACG|T|301 silent|ACC>ACT|T|301 T|301|S T|301|I 0 0 0 0 -0.9675356412919948 Q08887 0.9491789937019348 0.9472420215606691 0.8010663986206055 0.3016284108161926 46.20857326525788 40.0 0.0 no 14242 chrXV_1035586r 35126 essential YOR372C 863 + CGCGTTAGTGGATTTTCAGA A|289|G A|289|V 0 0 0 0 1.0018835485107285 Q08887 0.9484469890594482 0.9504740238189696 0.0 0.0 48.10689147256011 45.0 0.0 no 14243 chrXV_1035598r 35127 essential YOR372C 851 + ATCGTCTAACAGCGCGTTAG S|285|W S|285|L S|286|C S|286|F 0 0 0 0 0.35547829750406457 Q08887 0.9288619756698608 0.9298099875450134 0.945252001285553 0.9294660091400146 0.003477760124951601 0.01707470789551735 0.004756116308271885 0.003188989358022809 48.41061074540619 50.0 0.0 no 14244 chrXV_1035668 35128 essential YOR372C 784 - TCCATATGGTGTCAACGACA G|268|R G|268|R G|268|A G|268|E 0 0 0 0 0.3654088231905576 Q08887 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.0 0.0 0.0 0.0 47.562389973281604 45.0 0.0 no 14245 chrXV_1035741 35129 essential YOR372C 711 - TTCATGTCAATCTTACTCAG M|243|I M|243|I 0 0 0 0 0.4932071836891062 Q08887 0.9553959965705872 0.9553959965705872 0.10230421274900436 0.10230421274900436 42.05294733013875 35.0 0.0 no 14246 chrXV_1035776 35130 essential YOR372C 676 - TGCGCCGGTGCATGAAGATG A|232|P A|232|T G|231|A G|231|D 0 1 0 0 -1.3451640096947646 Q08887 0.9573720097541808 0.9523990154266356 0.9499930143356324 0.9446240067481996 0.371008038520813 0.5973610877990723 0.8237053155899048 0.6319884657859802 52.871708542846136 60.0 0.0 no 14247 chrXV_1035780r 35131 essential YOR372C 669 + ACACCCTCATCTTCATGCAC P|225|A P|225|S T|224|R T|224|I 0 1 0 0 -0.4786116106824933 Q08887 0.9562489986419678 0.9498909711837769 0.9476869702339172 0.9472420215606691 0.4646726250648498 0.8162244558334351 0.5119485259056091 0.2585963308811188 54.09081204198521 50.0 0.0 no 14248 chrXV_1035807r 35132 essential YOR372C 642 + AACAATCTTTTGAAGAGTAA N|215|K silent|AAC>AAT|N|215 L|217|V L|217|F 0 0 0 0 0.4969113777368831 Q08887 0.9439849853515624 0.9512209892272948 0.9587849974632264 0.5988065004348755 0.6557676792144775 0.7147390842437744 33.45107407325213 25.0 0.0 no 14249 chrXV_1035847 35133 essential YOR372C 605 - AAACATTCTGTTGTTGACCT V|208|L V|208|I 0 0 0 0 -0.371971116657326 Q08887 0.9539830088615416 0.9574310183525084 0.37043237686157227 0.22475822269916532 43.877514817363526 35.0 0.0 no 14250 chrXV_1036009r 35135 essential YOR372C 440 + CTCTTTACCCAGCGAATTTT S|148|C S|148|F 0 0 0 0 0.4668341517698486 Q08887 0.945252001285553 0.9294660091400146 0.04729551076889038 0.0324425995349884 48.4693219525206 40.0 0.0 no 14251 chrXV_1036035 35136 essential YOR372C 417 - CCGAACTGCAAAACAGAAGA G|146|R G|146|S Q|144|H silent|CAG>CAA|Q|144 0 0 0 0 -0.3696861365559281 Q08887 0.941340982913971 0.951104998588562 0.9570760130882264 0.11145580559968947 0.2786710262298584 0.1377064883708954 40.18535159785074 45.0 0.0 no 14252 chrXV_1036035r 35137 essential YOR372C 414 + CCTTCTTCTGTTTTGCAGTT P|139|R P|139|L S|140|C S|140|F 0 0 0 0 -0.9513488267376488 Q08887 0.9432820081710817 0.9430609941482544 0.945252001285553 0.9294660091400146 0.0 0.0 0.0 0.0 52.84930732594637 40.0 0.0 no 14253 chrXV_1036092 35139 essential YOR372C 360 - TCTGTCCTTGTGACAGCAGG D|127|H D|127|N R|125|S silent|AGG>AGA|R|125 0 0 0 0 -0.9816194935357592 Q08887 0.9486550092697144 0.956179976463318 0.9087679982185364 0.12793223559856415 0.5806803107261658 0.7256062626838684 55.17339304532362 55.00000000000001 0.0 no 14254 chrXV_1036379 35142 essential YOR372C 73 - ATCTGCATTATTGTCCGTAG D|31|H D|31|N A|30|P A|30|T 0 0 0 0 0.29868045905191226 Q08887 0.9486550092697144 0.956179976463318 0.9573720097541808 0.9523990154266356 0.00766282808035612 0.023225441575050357 0.1195271834731102 0.5909605622291565 47.639852442311394 40.0 0.0 no 14255 chrXV_1036428r 35145 essential YOR372C 21 + CAGCAAAATTATACCTCAAC Q|9|E Q|9|* 0 0 0 0 -0.6579135734912671 Q08887 0.9590039849281312 38.09020763379948 35.0 0.0 no 14256 chrXV_1036912 35148 essential YOR373W 78 + TCGAACGCGCACAGTAACAG S|27|W S|27|L N|28|K silent|AAC>AAT|N|28 NUD1 851.0 0 0 0 0 -0.30367975753143306 P32336 0.03322109580039978 0.3481230139732361 0.7824082374572754 46.51089785436113 55.00000000000001 1.0 no 14257 chrXV_1037134 35151 essential YOR373W 300 + AAGCAGTATTTCCCTGGTAT Q|102|E Q|102|* NUD1 851.0 0 0 0 0 0.0940619266184965 P32336 0.09128609299659728 50.28129438646391 40.0 1.0 no 14258 chrXV_1037146r 35152 essential YOR373W 315 - CCACCGCCGCTACCAATACC G|111|A G|111|D G|112|R G|112|S NUD1 851.0 0 1 0 0 0.03892273081529235 P32336 0.4111211895942688 0.8363919258117676 0.09599506855010986 0.6351470351219177 58.793484267553204 65.0 1.0 no 14259 chrXV_1037170 35153 essential YOR373W 336 + ACCAACTTTGGTGGCGCTGT silent|ACC>ACG|T|113 silent|ACC>ACT|T|113 T|113|S T|113|I NUD1 851.0 0 0 0 1 0.3260592550789455 P32336 0.8546724319458008 0.2513687908649445 55.968254228102076 55.00000000000001 1.0 no 14260 chrXV_1037171r 35154 essential YOR373W 340 - ACCAACAGCGCCACCAAAGT G|120|R G|120|S G|120|A G|120|D NUD1 851.0 0 0 0 0 -0.9099045368341454 P32336 0.25837239623069763 0.7657581567764282 0.3832402229309082 0.6788846850395203 52.84771132032164 55.00000000000001 1.0 no 14261 chrXV_1037209r 35155 essential YOR373W 378 - CTCACAATGAGATCCGATTC silent|GTG>GTC|V|132 silent|GTG>GTA|V|132 V|132|L V|132|M NUD1 851.0 0 0 0 0 0.5112902470668571 P32336 0.8002158403396606 0.05682382360100746 44.55453111596614 45.0 1.0 no 14262 chrXV_1037574 35160 essential YOR373W 740 + TAACGCTAGAACGAAGGAGG N|248|K silent|AAC>AAT|N|248 A|249|G A|249|V NUD1 851.0 0 1 0 0 0.457440161796053 P32336 0.9412055015563964 0.376270204782486 0.27824172377586365 41.369219952751045 50.0 1.0 no 14263 chrXV_1037647 35161 essential YOR373W 813 + TCGTCCTCTCAAACTCAATC S|272|W S|272|L S|273|C S|273|F NUD1 851.0 0 0 0 0 0.11312484385010388 P32336 0.01031032856553793 0.0513005256652832 0.15979714691638947 0.4707159698009491 46.66080461122607 45.0 1.0 no 14264 chrXV_1037651r 35162 essential YOR373W 820 - TCTGCCTGATTGAGTTTGAG R|280|T R|280|K G|279|A G|279|D NUD1 851.0 0 0 0 0 -1.344594955269056 P32336 0.5889723896980286 0.8826672434806824 0.8546320199966431 0.5750566720962524 48.56272167652668 45.0 1.0 no 14265 chrXV_1037698 35163 essential YOR373W 864 + CCATTGAACACTATTTCACC P|289|R P|289|L NUD1 851.0 0 0 0 0 1.4571160134075405 P32336 0.4046693444252014 0.22174440324306488 44.884305873988296 40.0 1.0 no 14266 chrXV_1037706 35164 essential YOR373W 872 + CACTATTTCACCCGGTCAAT T|292|S T|292|I NUD1 851.0 0 0 0 0 -0.6312775348785988 P32336 0.03898912668228149 0.12362601608037947 49.82394019632369 45.0 1.0 no 14267 chrXV_1037707 35165 essential YOR373W 873 + ACTATTTCACCCGGTCAATT T|292|S T|292|I NUD1 851.0 0 0 0 0 0.08734509240456664 P32336 0.03898912668228149 0.12362601608037947 48.881068277583104 40.0 1.0 no 14268 chrXV_1037716r 35166 essential YOR373W 885 - AACTGATATCCCAATTGACC Q|301|H silent|CAG>CAA|Q|301 NUD1 851.0 0 0 0 0 -0.7482389574893096 P32336 0.02656059898436069 44.807164525410144 40.0 1.0 no 14269 chrXV_1037717r 35167 essential YOR373W 886 - AAACTGATATCCCAATTGAC Q|301|H silent|CAG>CAA|Q|301 NUD1 851.0 0 0 0 0 -0.4415407030877952 P32336 0.02656059898436069 39.90801781084304 35.0 1.0 no 14270 chrXV_1037731 35168 essential YOR373W 897 + TATCAGTTTAACCATACACA Q|301|E Q|301|* NUD1 851.0 0 0 0 0 -0.8410539102881851 P32336 0.08908264338970184 40.610761758239505 30.0 1.0 no 14271 chrXV_1037739 35169 essential YOR373W 905 + TAACCATACACACGGCGCAT N|303|K silent|AAC>AAT|N|303 H|304|D H|304|Y NUD1 851.0 0 0 0 0 -0.04712910600920234 P32336 0.11671040207147597 0.5121091008186339 0.12567877769470215 49.052219538734725 50.0 1.0 no 14272 chrXV_1037742r 35170 essential YOR373W 911 - GATCCCATGCGCCGTGTGTA D|310|H D|310|N W|309|C W|309|* NUD1 851.0 0 0 0 0 0.1629710016030007 P32336 0.2824609577655792 0.5923954844474792 0.0 60.180431873504354 60.0 1.0 no 14273 chrXV_1037767r 35172 essential YOR373W 936 - ACATCTAAGCCCTGGTTCAG V|319|L V|319|M D|318|H D|318|N NUD1 851.0 0 0 0 0 0.5885050480204294 P32336 0.11668602377176285 0.02226095087826252 0.0 0.0 52.5909225953975 50.0 1.0 no 14274 chrXV_1037775r 35173 essential YOR373W 944 - AACTCGACACATCTAAGCCC S|321|T S|321|N silent|TCG>TCC|S|320 silent|TCG>TCA|S|320 NUD1 851.0 0 0 0 0 0.17365253326856514 P32336 0.0 0.0 48.726252929694795 50.0 1.0 no 14275 chrXV_1037826 35174 essential YOR373W 992 + CCAGTCCCAGTTCGCCACAA Q|332|E Q|332|* S|333|C S|333|F NUD1 851.0 0 0 0 0 -2.179447919813452 P32336 0.9803335070610046 0.028105704113841057 0.029717152938246724 60.18043835353717 60.0 1.0 yes 14276 chrXV_1037836 35176 essential YOR373W 1002 + TTCGCCACAATGGTACCAAC F|335|L silent|TTC>TTT|F|335 A|336|G A|336|V NUD1 851.0 0 0 0 0 -4.0892482409746815 P32336 0.4850326478481293 0.56320720911026 0.6961225867271423 49.207430711350746 50.0 1.0 yes 14277 chrXV_1037884r 35178 essential YOR373W 1053 - GCCTTCTTATCTAGAATTGA K|357|N silent|AAG>AAA|K|357 A|358|P A|358|T NUD1 851.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.06357073120556997 P32336 0.5344143509864807 0.2384334355592728 0.4603631496429443 44.771914474348314 35.0 1.0 no 14278 chrXV_1038132r 35183 essential YOR373W 1301 - TATCTTCAACCCGTTCAGCG D|440|H D|440|N E|439|Q E|439|K NUD1 851.0 0 0 0 0 -1.0640524996661882 P32336 0.020524578168988228 0.25837627053260803 0.43607717752456665 0.6197059154510498 51.50318895384777 50.0 1.0 no 14279 chrXV_1038240 35184 essential YOR373W 1406 + TCCAAGCTATGATTCCGATT P|470|R P|470|L P|470|A P|470|S NUD1 851.0 0 1 0 0 0.1971814901554419 P32336 0.15166793763637546 0.10465716570615767 0.38510122895240784 0.3852013051509857 47.64779837336221 40.0 1.0 no 14280 chrXV_1038269 35185 essential YOR373W 1435 + TCCTGAAAGTTGACCTATCA L|480|V silent|CTG>TTG|L|480 I|479|M silent|ATC>ATT|I|479 NUD1 851.0 0 0 0 0 0.18630640531390166 P32336 0.6276915669441223 0.02503105811774731 45.902076751319335 40.0 1.0 no 14281 chrXV_1038270r 35186 essential YOR373W 1439 - CCCTTGATAGGTCAACTTTC R|486|T R|486|K R|486|S silent|AGG>AGA|R|486 NUD1 851.0 0 0 0 0 -0.07750281414892783 P32336 0.3751960396766663 0.837269127368927 0.634975254535675 49.2285257546809 45.0 1.0 no 14282 chrXV_1038270 35187 essential YOR373W 1436 + CCTGAAAGTTGACCTATCAA L|480|V silent|CTG>TTG|L|480 NUD1 851.0 0 0 0 0 1.5493304757813993 P32336 0.6276915669441223 43.498615220589215 40.0 1.0 no 14283 chrXV_1038282r 35188 essential YOR373W 1451 - TCTTCAGTTTGCCCCTTGAT K|490|N silent|AAG>AAA|K|490 silent|CTG>CTC|L|489 silent|CTG>CTA|L|489 NUD1 851.0 0 0 0 0 -1.5221296280998335 P32336 0.5058609247207642 56.475023885445005 45.0 1.0 no 14284 chrXV_1038452r 35190 essential YOR373W 1621 - GCATTCCAGATCGTGGAATC C|547|S C|547|Y E|546|Q E|546|K NUD1 851.0 0 0 0 0 -0.926079029025778 P32336 0.9924026131629944 0.13620728254318235 0.0 0.0 49.623203894919975 50.0 1.0 no 14285 chrXV_1038559 35192 essential YOR373W 1725 + AACTCCATCCAATCCTTAGA N|576|K silent|AAC>AAT|N|576 S|577|C S|577|F NUD1 851.0 0 0 0 0 -0.6141689238061528 P32336 0.0 0.06213629245758056 0.05582701414823532 48.18829438349451 40.0 1.0 no 14286 chrXV_1038560 35193 essential YOR373W 1726 + ACTCCATCCAATCCTTAGAA S|577|C S|577|F N|576|K silent|AAC>AAT|N|576 NUD1 851.0 0 0 0 0 -0.4683451266577189 P32336 0.06213629245758056 0.05582701414823532 0.0 48.18829438349445 40.0 1.0 no 14287 chrXVI_35259 35197 high_effect YPL268W 23 + CCAAAGGTTTAATCTTACAA Q|9|E Q|9|* 0 0 0 0 -0.06345027139580611 P32383 37.982907927369695 30.0 1.0 no 14288 chrXVI_35259r 35198 high_effect YPL268W 26 - CCTTTGTAAGATTAAACCTT K|15|N silent|AAG>AAA|K|15 0 0 0 0 0.8966614118747576 P32383 40.42070495905927 30.0 1.0 no 14289 chrXVI_35684r 35203 high_effect YPL268W 451 - ACCGATTCTGATGTCTTTAA G|157|R G|157|S G|157|A G|157|D 0 0 0 0 0.20706193030940184 P32383 0.02004552073776722 0.12283171713352205 0.3337621986865997 0.022130753844976425 43.995510700670756 35.0 1.0 no 14290 chrXVI_35709 35205 high_effect YPL268W 473 + TACGGCGAGTACTTATCAAG T|159|R T|159|M A|160|G A|160|V 0 0 0 0 0.3721571016412801 P32383 0.15971696376800534 0.3796115517616272 0.12730395793914795 0.012130429968237877 43.7180892520712 45.0 1.0 no 14291 chrXVI_35848 35206 high_effect YPL268W 612 + ACATTCTTAAGCTGCATTTG T|205|R T|205|I F|206|L silent|TTC>TTT|F|206 0 0 0 0 0.09139615221202356 P32383 0.4313632547855377 0.5687087178230286 0.14420846104621887 43.21431876057454 35.0 1.0 no 14292 chrXVI_36028 35208 high_effect YPL268W 792 + TTTCATATTTATGTGTCAAC H|266|D H|266|Y 0 0 0 0 0.4405323912051223 P32383 0.05825942754745484 0.01999478973448276 37.37658343415876 25.0 1.0 no 14293 chrXVI_36125 35209 high_effect YPL268W 889 + TCATTAAAATCTTAAAGAAT F|297|L silent|TTC>TTT|F|297 0 0 0 0 0.4102706317465715 P32383 0.0 27.66484765460001 15.0 1.0 no 14294 chrXVI_36132 35210 high_effect YPL268W 896 + AATCTTAAAGAATAGGAAAG I|300|M silent|ATC>ATT|I|300 0 0 0 0 -0.3342188129839401 P32383 0.21404463052749634 28.66696679211833 25.0 1.0 no 14295 chrXVI_36388r 35215 high_effect YPL268W 1155 - GCAATAAAATAATGGTTTAA A|392|P A|392|T 0 1 0 0 -1.211421909988733 P32383 0.03737402334809303 0.04513099417090416 30.55640791928454 20.0 1.0 no 14296 chrXVI_36414 35216 high_effect YPL268W 1178 + TTCACATAATACTTATTTAT S|394|* S|394|L H|395|D H|395|Y 0 1 0 0 -2.7095773273523625 P32383 0.0 0.0 0.0 32.88168478811741 15.0 1.0 yes 14297 chrXVI_36415 35217 high_effect YPL268W 1179 + TCACATAATACTTATTTATT H|395|D H|395|Y S|394|* S|394|L 1 Series([], Name: modification, dtype: object) 0 0 0 -0.42900832848099896 P32383 0.0 0.0 0.0 32.88168478811741 15.0 1.0 no 14298 chrXVI_36483r 35220 high_effect YPL268W 1250 - CGCACCTACAACCTTGTTGT C|423|S C|423|Y R|422|S silent|AGG>AGA|R|422 0 0 0 0 -1.0297538581089922 P32383 0.687104344367981 0.01495459955185652 0.0 52.432894535044454 50.0 1.0 no 14299 chrXVI_36575r 35221 high_effect YPL268W 1342 - CACGCGTATAACTGTTTTTA V|454|L V|454|M R|453|P R|453|H 0 0 0 0 0.4748460088449194 P32383 0.15448875725269318 0.04437926411628723 0.263172447681427 0.11680738627910615 42.38123149106615 35.0 1.0 no 14300 chrXVI_36940 35224 high_effect YPL268W 1704 + ATGCAACGCATCAAAAGAAT Q|570|E Q|570|* R|571|G R|571|C 0 0 0 0 -0.16751736881383833 P32383 0.7600452899932861 0.060015764087438576 0.008614611811935902 37.78769063620956 35.0 1.0 no 14301 chrXVI_37045r 35225 high_effect YPL268W 1812 - TGCGCTATCGTTTTGGACTC silent|GCG>GCC|A|610 silent|GCG>GCA|A|610 A|610|P A|610|T 0 0 0 0 -0.6151371393511333 P32383 0.10718847811222076 1.0 51.39462141228421 50.0 1.0 no 14302 chrXVI_39313r 35232 essential YPL266W 195 - ACAGTTAGGTTACCTGTACC V|72|L V|72|I DIM1 DIMethylase 318.0 0 0 0 0 0.009509220631519544 P41819 0.1478288322687149 0.2535720467567444 -1.2225600481033323 -0.970960021018982 50.67619953900345 45.0 1.0 no 14303 chrXVI_39317 35233 essential YPL266W 196 + GTACAGGTAACCTAACTGTA T|67|R T|67|I DIM1 DIMethylase 318.0 0 0 0 0 -0.03869686596477978 P41819 0.0 0.0 44.128080529164656 40.0 1.0 no 14304 chrXVI_39510 35238 essential YPL266W 389 + TTACCAGATCTCATCGCCTC Y|131|* silent|TAC>TAT|Y|131 Q|132|E Q|132|* DIM1 DIMethylase 318.0 0 0 0 0 -0.1996263484619984 P41819 0.005601425189524889 53.49908852073219 50.0 1.0 no 14305 chrXVI_39705 35242 essential YPL266W 584 + CTTCAGACCGCCACCACAAG F|196|L silent|TTC>TTT|F|196 DIM1 DIMethylase 318.0 0 0 0 0 -0.16651301925410344 P41819 0.0 2.2486400604248047 54.19507534171913 60.0 1.0 no 14306 chrXVI_39731r 35243 essential YPL266W 613 - AATCTCTAGTCTAACAACGC E|210|D silent|GAG>GAA|E|210 E|210|Q E|210|K DIM1 DIMethylase 318.0 0 0 0 0 1.2705605498366666 P41819 0.08016913384199142 0.14706815779209134 0.0910518318414688 41.69408009470135 40.0 1.0 no 14307 chrXVI_39718r 35244 essential YPL266W 600 - ACAACGCTGGATTCCACTTG V|207|L V|207|I V|206|L V|206|I DIM1 DIMethylase 318.0 0 0 0 0 -1.4855009577805305 P41819 0.048686780035495765 0.15839292109012604 0.010894524864852428 0.2447428703308105 48.856088205253066 50.0 1.0 no 14308 chrXVI_67756 35248 essential YPL255W 31 + GCATTTTTGGTCTTTTCAAA silent|GGC>GGG|G|11 silent|GGC>GGT|G|11 BBP1 Bfr1 Binding Protein 385.0 0 0 0 0 0.03536669489860768 Q12365 42.94361159414808 30.0 1.0 no 14309 chrXVI_67875 35251 essential YPL255W 150 + ACAAATTTTTCTATGAAGTT T|51|R T|51|I BBP1 Bfr1 Binding Protein 385.0 0 0 0 0 0.945514510598572 Q12365 0.0 0.0 33.961175782639536 20.0 1.0 no 14310 chrXVI_67951 35254 essential YPL255W 226 + GTCTGGATTCAACGCTCCAT L|77|V silent|CTG>TTG|L|77 BBP1 Bfr1 Binding Protein 385.0 0 1 0 0 -1.5222745157649955 Q12365 0.12697048485279086 52.39221353345624 50.0 1.0 no 14311 chrXVI_67989r 35255 essential YPL255W 267 - AAGCCGTTCTCGTTGTACTC G|95|A G|95|D G|95|R G|95|S BBP1 Bfr1 Binding Protein 385.0 0 0 0 0 1.497844879715408 Q12365 0.329294890165329 1.0 0.18605920672416687 0.4651830792427063 52.43766651717789 50.0 1.0 no 14312 chrXVI_68007 35256 essential YPL255W 282 + GGCTTTAACTCAATTGTTAA silent|GGC>GGG|G|95 silent|GGC>GGT|G|95 BBP1 Bfr1 Binding Protein 385.0 0 0 0 0 0.864397549532509 Q12365 39.62506369255272 30.0 1.0 no 14313 chrXVI_68036r 35257 essential YPL255W 314 - ATCGTATTCTCTCTTTGCTG R|111|P R|111|Q BBP1 Bfr1 Binding Protein 385.0 0 1 0 0 1.041383102777607 Q12365 0.054463908076286316 0.3261542022228241 48.30552264156057 40.0 1.0 no 14314 chrXVI_68093 35260 essential YPL255W 368 + ACCACTTCGTAACGAACCTA P|124|R P|124|L P|124|A P|124|S BBP1 Bfr1 Binding Protein 385.0 0 0 0 0 -0.07984940225168835 Q12365 0.01966906152665615 0.026372004300355908 0.3836706876754761 0.09129533916711807 46.68615053958831 45.0 1.0 no 14315 chrXVI_68103 35262 essential YPL255W 378 + AACGAACCTACGGATACATT N|127|K silent|AAC>AAT|N|127 P|129|A P|129|S BBP1 Bfr1 Binding Protein 385.0 0 0 0 0 -0.4590652364682866 Q12365 0.8900843858718872 0.17290014028549194 0.5261800885200499 41.77976237501406 40.0 1.0 no 14316 chrXVI_68125 35263 essential YPL255W 400 + GTCACAGACTACACACAAAA H|135|D H|135|Y H|135|Q silent|CAC>CAT|H|135 BBP1 Bfr1 Binding Protein 385.0 0 0 0 0 0.4059985110028724 Q12365 0.33892276883125305 1.0 0.4345103204250336 39.75592160940499 40.0 1.0 no 14317 chrXVI_68262r 35266 essential YPL255W 540 - TCTTTAACCGATAACTTATA D|187|H D|187|N BBP1 Bfr1 Binding Protein 385.0 0 0 0 0 0.4470358342980843 Q12365 0.07628421485424043 1.0 37.091070685231216 25.0 1.0 no 14318 chrXVI_68263r 35267 essential YPL255W 541 - ATCTTTAACCGATAACTTAT D|187|H D|187|N BBP1 Bfr1 Binding Protein 385.0 0 0 0 0 0.04892720297765557 Q12365 0.07628421485424043 1.0 37.6086930041501 25.0 1.0 no 14319 chrXVI_68301r 35268 essential YPL255W 579 - TCACGTTTTGTTAAGGGAGA R|199|P R|199|H D|200|H D|200|N BBP1 Bfr1 Binding Protein 385.0 0 1 0 0 -0.2714700286626116 Q12365 0.337319940328598 0.2349371463060379 0.5838620662689209 0.7534922957420349 44.54809913194402 40.0 1.0 no 14320 chrXVI_68429 35269 essential YPL255W 704 + AGACCTGGAAGATTTGTGTG D|236|E silent|GAC>GAT|D|236 L|237|V silent|CTG>TTG|L|237 BBP1 Bfr1 Binding Protein 385.0 0 0 0 0 0.19154570431519885 Q12365 1.0 0.04611049965023994 45.517422276494635 45.0 1.0 no 14321 chrXVI_69552r 35275 high_effect YPL254W 70 - CGGCTTCATATATGCATTCG K|29|N silent|AAG>AAA|K|29 M|28|I M|28|I HFI1 Histone H2A Functional Interactor 488.0 0 0 0 0 0.8586415520119917 Q12060 0.5337511897087097 0.4796653389930725 0.4796653389930725 47.080360395496655 45.0 1.0 no 14322 chrXVI_69602 35280 high_effect YPL254W 117 + AATCATACCGAGCCTAACAA H|41|D H|41|Y HFI1 Histone H2A Functional Interactor 488.0 0 0 0 0 0.4544343425195648 Q12060 0.6430733799934387 0.536270797252655 43.805456189737015 40.0 1.0 no 14323 chrXVI_69577r 35281 high_effect YPL254W 95 - TGACGGCAGGACTACCAATT V|38|L V|38|I A|37|P A|37|T HFI1 Histone H2A Functional Interactor 488.0 0 0 0 0 -0.7259002820954968 Q12060 0.6371649503707886 0.4222848117351532 0.1444348245859146 0.8127254843711853 48.878037517484465 50.0 1.0 no 14324 chrXVI_69644r 35282 high_effect YPL254W 162 - ATTCTCTGATTTGGTCCCTG R|60|T R|60|K Q|59|H silent|CAG>CAA|Q|59 HFI1 Histone H2A Functional Interactor 488.0 0 0 0 0 0.16486422220510566 Q12060 0.0 0.0 0.11653191596269608 52.56703715015624 45.0 1.0 no 14325 chrXVI_69653 35283 high_effect YPL254W 168 + CCAAATCAGAGAATTGATTT P|57|R P|57|L Q|59|E Q|59|* HFI1 Histone H2A Functional Interactor 488.0 0 0 0 0 0.07785056081162019 Q12060 0.5566474795341492 0.3258596062660217 0.4613061547279358 37.141455951856415 30.0 1.0 no 14326 chrXVI_69768r 35284 high_effect YPL254W 286 - TTCATTAGAAAGTTCCTTTC E|102|Q E|102|K HFI1 Histone H2A Functional Interactor 488.0 0 0 0 0 0.36642590531950414 Q12060 0.2617630064487457 0.2966070771217346 40.56047636029672 30.0 1.0 no 14327 chrXVI_69696r 35285 high_effect YPL254W 214 - GCTTTCTTTTCCCAATAGTG S|78|T S|78|N E|77|Q E|77|K HFI1 Histone H2A Functional Interactor 488.0 0 0 0 0 0.7936474440754924 Q12060 0.05143250524997711 1.0 0.12504753470420835 0.12974317371845245 49.41458370159272 40.0 1.0 no 14328 chrXVI_69778 35286 high_effect YPL254W 293 + ACTTTCTAATGAATTAGAGC L|99|V L|99|F S|100|C S|100|F HFI1 Histone H2A Functional Interactor 488.0 0 0 0 0 -1.0147781907872782 Q12060 0.021407190710306168 0.02011704444885254 0.13197535276412964 0.05892616882920265 37.04149643845057 30.0 1.0 no 14329 chrXVI_70049r 35290 high_effect YPL254W 567 - AGTCTATTTCGATCATTTAG R|195|T R|195|K HFI1 Histone H2A Functional Interactor 488.0 0 0 0 0 1.000385268736434 Q12060 0.0 0.0 40.07491337136583 30.0 1.0 no 14330 chrXVI_70069 35291 high_effect YPL254W 584 + ACTTAAAATGATCACGAAAG L|196|V L|196|F HFI1 Histone H2A Functional Interactor 488.0 0 0 0 0 1.1611779321069071 Q12060 0.11204690486192703 0.048741277307271964 31.888711504670137 30.0 1.0 no 14331 chrXVI_70158r 35293 high_effect YPL254W 676 - ACTTTCTGGATTGGTTACAA S|232|T S|232|N E|231|Q E|231|K HFI1 Histone H2A Functional Interactor 488.0 0 1 0 0 1.1059956847954289 Q12060 1.0 0.05754988640546799 0.05233046039938927 0.04154390096664429 43.513699401607425 35.0 1.0 no 14332 chrXVI_70295 35294 high_effect YPL254W 810 + TCGTTTTACTTAAGAATGGT S|271|W S|271|L HFI1 Histone H2A Functional Interactor 488.0 0 0 0 0 -0.3305103937935687 Q12060 0.004818502347916365 0.019481699913740158 39.35932416466238 30.0 1.0 no 14333 chrXVI_70527r 35298 high_effect YPL254W 1045 - ATCATCTAACTGCTTAATTT D|355|H D|355|N D|354|H D|354|N HFI1 Histone H2A Functional Interactor 488.0 0 0 0 0 0.3478270511301799 Q12060 38.670863468214115 25.0 1.0 no 14334 chrXVI_73506 35299 essential YPL252C 356 - CATCATCTTCAGGTTCCGGC D|125|H D|125|N D|124|H D|124|N YAH1 Yeast Adrenodoxin Homolog 172.0 0 0 0 0 -0.8325648518414783 Q12184 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.0042707533575594425 0.009144594892859459 0.0 0.0 -0.11467999964952467 -0.25189998745918274 -0.22120000422000885 -0.4939000010490418 55.960788522205355 55.00000000000001 0.0 no 14335 chrXVI_73507 35300 essential YPL252C 355 - ATCATCTTCAGGTTCCGGCA D|125|H D|125|N D|124|H D|124|N YAH1 Yeast Adrenodoxin Homolog 172.0 0 0 0 0 -1.186853380606358 Q12184 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.0042707533575594425 0.009144594892859459 0.0 0.0 -0.11467999964952467 -0.25189998745918274 -0.22120000422000885 -0.4939000010490418 55.960788522205355 50.0 0.0 no 14336 chrXVI_73648 35312 essential YPL252C 214 - ACAGACTTCGTACGTCTTCT C|78|S C|78|Y V|77|L V|77|I YAH1 Yeast Adrenodoxin Homolog 172.0 0 0 0 0 0.329864254424436 Q12184 0.9421560168266296 0.9290120005607604 0.9539830088615416 0.9574310183525084 0.8198638558387756 0.7755246758460999 0.05711290985345841 0.032201286405324936 -0.32297998666763306 0.18648000061511996 2.9775600433349614 0.5820000171661377 0.01711999997496605 -0.8168799877166748 2.1698598861694336 2.5204598903656006 49.172722638581035 45.0 0.0 no 14337 chrXVI_73733r 35313 essential YPL252C 126 + ACGTCTTCGTTCTTAAACCA T|43|R T|43|M S|44|C S|44|F YAH1 Yeast Adrenodoxin Homolog 172.0 0 0 0 0 1.00415707651749 Q12184 0.9476869702339172 0.9502379894256592 0.945252001285553 0.9294660091400146 0.10345707833766936 0.044487036764621735 0.07788369059562683 0.006651177071034907 46.47161220473862 40.0 0.0 no 14338 chrXVI_77339r 35315 no_effect YPL249C 1992 + CTCTTCAATTACTATTTAAT silent|CTC>CTG|L|665 silent|CTC>CTT|L|665 F|666|L silent|TTC>TTT|F|666 GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 0 0 0 0.1418124002408817 Q12344 0.9387490153312684 0.0 34.76564704904632 20.0 0.0 no 14339 chrXVI_77340r 35316 no_effect YPL249C 1991 + ACTCTTCAATTACTATTTAA silent|CTC>CTG|L|665 silent|CTC>CTT|L|665 L|665|V L|665|F GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 0 0 0 0.074531614745705 Q12344 0.9512209892272948 0.9587849974632264 0.0 0.0 35.175578286072785 20.0 0.0 no 14340 chrXVI_77539r 35317 no_effect YPL249C 1792 + CCACAATGTACGCTACACAA T|599|R T|599|I silent|TCC>TCG|S|598 silent|TCC>TCT|S|598 GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 0 0 0 0.3739451487315953 Q12344 0.9476869702339172 0.9472420215606691 0.009308375418186188 0.010230472311377524 45.11812811777368 45.0 0.0 no 14341 chrXVI_77489 35318 no_effect YPL249C 1845 - ATTCTTAACACAAACTCTAA R|621|T R|621|K GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 0 0 0 0.2410085784615637 Q12344 0.932735025882721 0.955805003643036 0.0 0.0 34.55389794839164 25.0 0.0 no 14342 chrXVI_77579 35321 no_effect YPL249C 1755 - ATCAAGCGATTGTACAAAGA L|591|F silent|TTG>TTA|L|591 R|590|P R|590|H GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 0 0 0 -0.12327981342981932 Q12344 0.9587849974632264 0.9099509716033936 0.9570810198783876 0.0 0.01850486919283867 1.0 38.748571367488005 35.0 0.0 no 14343 chrXVI_77570r 35322 no_effect YPL249C 1761 + TACAATCGCTTGATCCGTGA Y|588|* silent|TAC>TAT|Y|588 R|590|G R|590|C GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 0 0 0 0.4338692029359053 Q12344 0.8994590044021606 0.8926740288734436 0.02826835587620735 0.011105756275355816 47.6262320614324 45.0 0.0 no 14344 chrXVI_77610r 35323 no_effect YPL249C 1721 + TCAATTTGATAGATTATTAG Q|575|E Q|575|* GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 0 0 0 -0.01570022273393179 Q12344 0.9590039849281312 0.16494955122470856 31.773673194964548 20.0 0.0 no 14345 chrXVI_77774 35325 no_effect YPL249C 1560 - CCTTGCGTGTACCCAACATC G|527|R G|527|S silent|ACG>ACC|T|525 silent|ACG>ACA|T|525 GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 0 0 0 0.2015469503333321 Q12344 0.941340982913971 0.951104998588562 0.0 0.0 54.564257980055466 55.00000000000001 0.0 no 14346 chrXVI_77814r 35328 no_effect YPL249C 1517 + GTCACTATACAAGGTAATAA S|507|* S|507|L L|508|V silent|CTA>TTA|L|508 GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 0 0 0 0.2536690156671221 Q12344 0.9298099875450134 0.9512209892272948 0.02696922980248928 0.0 36.375627035743655 30.0 0.0 no 14347 chrXVI_77932 35330 no_effect YPL249C 1402 - ATCTTCCATTTCTCTTGATT D|474|H D|474|N E|473|Q E|473|K GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 0 0 0 -0.8071706430444139 Q12344 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.008321171626448631 0.01761205866932869 0.05549769476056099 0.0912020057439804 46.38468257285035 30.0 0.0 no 14348 chrXVI_78124 35333 no_effect YPL249C 1210 - ATTCTCCACTTCGTTATACT E|409|D silent|GAG>GAA|E|409 E|409|Q E|409|K GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 0 0 0 0.38828321466326776 Q12344 0.94931298494339 0.956179976463318 0.9475290179252625 0.5622154474258423 0.5308904051780701 0.828765869140625 47.17842603214609 35.0 0.0 no 14349 chrXVI_78156r 35335 no_effect YPL249C 1175 + ATCGACATTTACGTCATTTC S|393|W S|393|L T|394|R T|394|I GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 0 0 0 -0.6057357591221914 Q12344 0.9288619756698608 0.9298099875450134 0.9476869702339172 0.9472420215606691 0.002151644555851817 0.00903151370584965 0.007327909115701914 0.007934950292110443 42.390567867252 35.0 0.0 no 14350 chrXVI_78268 35338 no_effect YPL249C 1066 - GATCAAATTAATTTCTGCAG L|361|F silent|TTG>TTA|L|361 GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 0 0 0 0.2362000625974268 Q12344 0.9587849974632264 0.0 36.448311266159074 30.0 0.0 no 14351 chrXVI_78289 35339 no_effect YPL249C 1045 - GGACTCTAATTGCGCAGTTT E|354|D silent|GAG>GAA|E|354 E|354|Q E|354|K GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 0 0 0 0.3574016071978042 Q12344 0.94931298494339 0.956179976463318 0.9475290179252625 0.7387962937355042 0.2559431493282318 0.3330881893634796 49.05169193834132 45.0 0.0 no 14352 chrXVI_78314r 35341 no_effect YPL249C 1017 + TATCATCATGTTCCTCTCAC H|341|D H|341|Y H|342|D H|342|Y GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 1 0 0 0.5995655564596265 Q12344 0.9473130106925964 0.9489949941635132 0.9473130106925964 0.9489949941635132 0.5779193043708801 0.4476637542247772 0.4373677670955658 0.2676946222782135 48.53406236618082 40.0 0.0 no 14353 chrXVI_78383 35342 no_effect YPL249C 951 - TTCATTTCTTCCTCTAGTGG M|323|I M|323|I GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 0 0 0 -0.1496155923390942 Q12344 0.9553959965705872 0.9553959965705872 0.10511065274477004 0.10511065274477004 49.71377949238689 40.0 0.0 no 14354 chrXVI_78393r 35343 no_effect YPL249C 938 + TGCTGTTCCACCGCCACTAG A|314|G A|314|V GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 0 0 0 -0.2237463230250488 Q12344 0.9484469890594482 0.9504740238189696 0.4290618002414704 0.4209849536418915 59.16991141140113 60.0 0.0 no 14355 chrXVI_78410 35344 no_effect YPL249C 924 - ACAGCATTCTTCGTCTTCGG V|315|L V|315|I A|314|P A|314|T GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 0 0 0 -0.2445136734628805 Q12344 0.9539830088615416 0.9574310183525084 0.9573720097541808 0.9523990154266356 0.03781192749738693 0.06173255294561386 0.4325911998748779 0.6577730774879456 51.92247343968928 50.0 0.0 no 14356 chrXVI_78450r 35345 no_effect YPL249C 881 + GTCACCAAAATTACCTCCAA S|295|* S|295|L P|296|A P|296|S GYP5 Gtpase-activating protein for Ypt Proteins 894.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.3648789317429413 Q12344 0.9298099875450134 0.9562489986419678 0.9498909711837769 0.13955256342887878 0.0 0.0 45.42513490198435 40.0 0.0 no 14357 chrXVI_78449r 35347 no_effect YPL249C 882 + TCACCAAAATTACCTCCAAG P|296|A P|296|S S|295|* S|295|L GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 1 0 0 -0.30536958698728456 Q12344 0.9562489986419678 0.9498909711837769 0.9298099875450134 0.0 0.0 0.13955256342887878 43.218702717301824 40.0 0.0 no 14358 chrXVI_78479 35348 no_effect YPL249C 855 - GTCGCAACATTTTGTCTAGG silent|GCG>GCC|A|291 silent|GCG>GCA|A|291 A|291|P A|291|T GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 0 0 1 -0.878497994618133 Q12344 0.9573720097541808 0.9523990154266356 0.2488929331302643 0.5792441964149475 47.23338688716717 45.0 0.0 no 14359 chrXVI_78485 35349 no_effect YPL249C 849 - ACATTTTGTCTAGGTGGTAA V|290|L V|290|I GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 1 0 0 0.2483712613751332 Q12344 0.9539830088615416 0.9574310183525084 0.8027471303939819 0.4901668429374695 44.340577046699536 35.0 0.0 no 14360 chrXVI_78595 35350 no_effect YPL249C 739 - TACTTTCCTAGCAGTTTCTG V|253|L V|253|I R|251|S silent|AGG>AGA|R|251 GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 1 0 0 -0.6651288559280325 Q12344 0.9539830088615416 0.9574310183525084 0.9087679982185364 0.3416912853717804 0.20933569967746732 0.6940656304359436 48.81568838800155 40.0 0.0 no 14361 chrXVI_78601r 35351 no_effect YPL249C 730 + ATCTTTCCTCAGAAACTGCT L|245|V L|245|F S|246|C S|246|F GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 1 0 0 -0.8946236096833127 Q12344 0.9512209892272948 0.9587849974632264 0.945252001285553 0.9294660091400146 0.3762331604957581 0.1900341510772705 0.052962996065616615 0.051270171999931335 47.47438717414235 40.0 0.0 no 14362 chrXVI_78673 35352 no_effect YPL249C 661 - TTCATTCAAGTTTATTCCTG E|227|Q E|227|K L|225|F silent|TTG>TTA|L|225 GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 0 0 0 -0.05981894482530084 Q12344 0.956179976463318 0.9475290179252625 0.9587849974632264 0.3684342801570892 0.4343322813510895 0.14820344746112826 42.17336516598022 30.0 0.0 no 14363 chrXVI_78728 35354 no_effect YPL249C 606 - TCATTTTCTGACGACCTTTC D|209|H D|209|N GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 0 0 0 0.4061436001508643 Q12344 0.9486550092697144 0.956179976463318 0.04652107134461403 0.41919654607772827 46.8311792647076 40.0 0.0 no 14364 chrXVI_78811 35355 no_effect YPL249C 523 - GTCATCGAGAAATTTACTCG D|181|H D|181|N D|180|H D|180|N GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 0 0 0 0.9971703721591948 Q12344 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.5807834267616272 0.5075444579124451 0.08510848879814148 0.605189323425293 40.352688089652986 40.0 0.0 no 14365 chrXVI_78948 35356 no_effect YPL249C 386 - TTTCAATATTCAGCCCATTT E|135|Q E|135|K GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 1 0 0 0.3157045699060819 Q12344 0.956179976463318 0.9475290179252625 0.12865160405635834 0.11476465314626695 45.735565359027134 30.0 0.0 no 14366 chrXVI_78989 35358 no_effect YPL249C 345 - ACATCTTTTTCAACATCCAA V|122|L V|122|M D|121|H D|121|N GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 1 0 0 0.5387572940190039 Q12344 0.9539830088615416 0.9587630033493042 0.9486550092697144 0.956179976463318 0.6555962562561035 0.146489217877388 0.1190493181347847 0.3994775414466858 42.04166348188352 30.0 0.0 no 14367 chrXVI_79065 35359 no_effect YPL249C 269 - TAACGTTTTGTTCAGTGATT V|96|L V|96|I GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 0 0 0 0.5024385533019605 Q12344 0.9539830088615416 0.9574310183525084 0.3766070008277893 0.5387744307518005 41.17305707134949 30.0 0.0 no 14368 chrXVI_79054r 35360 no_effect YPL249C 277 + AACAAAACGTTAATGAACAA Q|94|E Q|94|* GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 1 0 0 0.3744551406221495 Q12344 0.9590039849281312 1.0 30.19838067238498 25.0 0.0 no 14369 chrXVI_79117 35363 no_effect YPL249C 217 - TTCTTCTCTTGATACATTTG E|79|Q E|79|K E|78|Q E|78|K GYP5 Gtpase-activating protein for Ypt Proteins 894.0 0 0 0 0 -0.1879882477499994 Q12344 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.19681483507156367 0.3478228747844696 0.5036232471466064 0.7543367743492126 41.12666130865705 30.0 0.0 no 14370 chrXVI_88529 35369 essential YPL243W 12 + TCTCCAATCATTGCCACCTA P|6|A P|6|S S|5|C S|5|F SRP68 Signal Recognition Particle 599.0 0 0 0 0 0.2854272104613221 P38687 0.9562489986419678 0.9498909711837769 0.945252001285553 0.9294660091400146 0.191071093082428 0.042603570967912674 0.0 0.0 53.30363250751543 45.0 1.0 no 14371 chrXVI_88532r 35370 essential YPL243W 18 - TTACCATAGGTGGCAATGAT G|12|A G|12|D G|12|R G|12|S SRP68 Signal Recognition Particle 599.0 0 0 0 0 -2.232839704679872 P38687 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.0 0.0 0.0 0.0 45.96732751735829 40.0 1.0 yes 14372 chrXVI_88542r 35371 essential YPL243W 28 - TTCTGCACGATTACCATAGG E|16|Q E|16|K A|15|P A|15|T SRP68 Signal Recognition Particle 599.0 0 0 0 0 -6.329780471739046 P38687 0.956179976463318 0.9475290179252625 0.9573720097541808 0.9523990154266356 0.09754133224487303 0.07944974303245544 0.11881116777658465 0.31110918521881104 47.26699386909882 45.0 1.0 yes 14373 chrXVI_88639 35372 essential YPL243W 122 + CCGTTGCCATTTGGTCACCA R|42|G R|42|C C|43|W silent|TGC>TGT|C|43 SRP68 Signal Recognition Particle 599.0 0 0 0 0 0.2941621583523632 P38687 0.8994590044021606 0.8926740288734436 0.9286419749259948 0.1210683062672615 0.031118717044591907 0.022256754338741302 58.61045940768094 55.00000000000001 1.0 no 14374 chrXVI_88673 35373 essential YPL243W 156 + TACTCAAGTAAAAATAAGTA Y|53|* silent|TAC>TAT|Y|53 S|54|* S|54|L SRP68 Signal Recognition Particle 599.0 0 0 0 0 -0.6817734923074411 P38687 0.9298099875450134 0.00958781037479639 28.803191277601233 20.0 1.0 no 14375 chrXVI_88867 35376 essential YPL243W 350 + CTGCAAGACTGCTGATAAAT C|118|W silent|TGC>TGT|C|118 SRP68 Signal Recognition Particle 599.0 0 0 0 0 0.9516995665262676 P38687 0.9286419749259948 0.19385896623134613 41.28122608809434 40.0 1.0 no 14376 chrXVI_89040r 35378 essential YPL243W 526 - ATTCTTCAAGTGTTCCAATG K|181|N silent|AAG>AAA|K|181 L|180|F silent|TTG>TTA|L|180 SRP68 Signal Recognition Particle 599.0 0 0 0 0 0.6564642305765792 P38687 0.9355990290641784 0.9587849974632264 0.5290797352790833 0.0 43.26193046700872 35.0 1.0 no 14377 chrXVI_89113 35379 essential YPL243W 596 + GTACTCTCTCAAGCAGTACG Y|200|* silent|TAC>TAT|Y|200 S|201|C S|201|F SRP68 Signal Recognition Particle 599.0 0 0 0 0 0.37198547094908735 P38687 0.945252001285553 0.9294660091400146 0.1859286278486252 0.702799379825592 48.79305935007586 50.0 1.0 no 14378 chrXVI_89114 35380 essential YPL243W 597 + TACTCTCTCAAGCAGTACGC Y|200|* silent|TAC>TAT|Y|200 S|201|C S|201|F SRP68 Signal Recognition Particle 599.0 0 0 0 0 0.3645917977944303 P38687 0.945252001285553 0.9294660091400146 0.1859286278486252 0.702799379825592 49.93014013929138 50.0 1.0 no 14379 chrXVI_89392 35382 essential YPL243W 875 + TACACAGAGGCTATCAAAAT T|293|R T|293|I Q|294|E Q|294|* SRP68 Signal Recognition Particle 599.0 0 0 0 0 0.2932582208927509 P38687 0.9476869702339172 0.9472420215606691 0.9590039849281312 0.06027113646268845 0.045344192534685135 0.911120057106018 38.83073657936143 35.0 1.0 no 14380 chrXVI_89547r 35384 essential YPL243W 1033 - ATCTCTTTCACGAGATATAG D|351|H D|351|N R|350|T R|350|K SRP68 Signal Recognition Particle 599.0 0 0 0 0 -3.262316759893616 P38687 0.9486550092697144 0.956179976463318 0.932735025882721 0.955805003643036 0.5218530297279358 0.6296825408935547 0.4017266631126404 0.6037986278533936 40.6282337465114 35.0 1.0 yes 14381 chrXVI_89574 35385 essential YPL243W 1057 + TTACTCATTTATGGAATCAA T|354|S T|354|I H|355|D H|355|Y SRP68 Signal Recognition Particle 599.0 0 0 0 0 0.3688811353577725 P38687 0.9491789937019348 0.9472420215606691 0.9473130106925964 0.9489949941635132 0.7270756363868713 0.17561201751232147 0.4831009209156037 0.5743921399116516 36.46741889950988 25.0 1.0 no 14382 chrXVI_89699r 35387 essential YPL243W 1185 - TCGTCATCTGAATACACACC E|402|Q E|402|K D|401|H D|401|N SRP68 Signal Recognition Particle 599.0 0 0 0 0 -0.2783743020771794 P38687 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.4056278467178345 0.3221606612205505 0.006528584752231836 0.01707351580262184 45.959452628648656 45.0 1.0 no 14383 chrXVI_89731r 35388 essential YPL243W 1217 - ACAGCTTGCATAAGTCTAAT silent|CTG>CTC|L|412 silent|CTG>CTA|L|412 K|411|N silent|AAG>AAA|K|411 SRP68 Signal Recognition Particle 599.0 0 0 0 0 -0.33619689084489 P38687 0.9355990290641784 0.1238544136285782 42.94130385994515 35.0 1.0 no 14384 chrXVI_89755 35389 essential YPL243W 1238 + TTTCCAGTTATTTCTGAATA F|414|L silent|TTC>TTT|F|414 Q|415|E Q|415|* SRP68 Signal Recognition Particle 599.0 0 0 0 0 -0.29266944251887644 P38687 0.9387490153312684 0.9590039849281312 0.02591519616544247 0.5732342600822449 40.50091572536086 25.0 1.0 no 14385 chrXVI_89782r 35390 essential YPL243W 1268 - TCGACTGATATAAAACACTC silent|TCG>TCC|S|429 silent|TCG>TCA|S|429 Q|428|H silent|CAG>CAA|Q|428 SRP68 Signal Recognition Particle 599.0 0 0 0 0 -0.6727563452653347 P38687 0.9570760130882264 0.010759985074400902 36.14632524799487 35.0 1.0 no 14386 chrXVI_91727 35392 essential YPL242C 3363 - AACAATTCCAATTTGGGGCT L|1127|F silent|TTG>TTA|L|1127 IQG1 IQGAP-related protein 1495.0 0 1 0 0 -0.06381185341502983 Q12280 0.9587849974632264 0.02953751012682915 45.89838391682474 40.0 0.0 no 14387 chrXVI_91778 35393 essential YPL242C 3312 - TCTCCCTCTTGTTCATACTC G|1110|A G|1110|E D|1111|H D|1111|N IQG1 IQGAP-related protein 1495.0 0 0 0 0 0.35272145922029896 Q12280 0.9499930143356324 0.9438679814338684 0.9486550092697144 0.956179976463318 0.6352855563163757 0.2954249382019043 0.029756551608443264 0.08501441776752472 54.16630711350752 45.0 0.0 no 14388 chrXVI_91800 35395 essential YPL242C 3290 - GATCTACTAACACATTATAA D|1103|H D|1103|N V|1102|L V|1102|I IQG1 IQGAP-related protein 1495.0 0 0 0 0 0.1374915433541508 Q12280 0.9486550092697144 0.956179976463318 0.9539830088615416 0.9574310183525084 0.01774829067289829 0.07131559401750565 0.9533658027648926 0.7320753335952759 34.34917187335793 25.0 0.0 no 14389 chrXVI_91911r 35397 essential YPL242C 3176 + TGACATTCTAATGAAATCCT D|1060|E silent|GAC>GAT|D|1060 IQG1 IQGAP-related protein 1495.0 0 0 0 0 0.3199058035986898 Q12280 0.9532920122146606 1.0 38.365153129003204 30.0 0.0 no 14390 chrXVI_91983r 35398 essential YPL242C 3104 + GTCTGAATATTTGGTCAACC S|1036|C S|1036|F IQG1 IQGAP-related protein 1495.0 0 0 0 0 0.4239819538550239 Q12280 0.945252001285553 0.9294660091400146 0.05066076293587685 0.16118621826171875 44.17192742688383 40.0 0.0 no 14391 chrXVI_92154 35403 essential YPL242C 2936 - CCATTTCAATCGCGTGCCAT M|985|I M|985|I E|984|Q E|984|K IQG1 IQGAP-related protein 1495.0 0 0 0 0 0.11237739888957636 Q12280 0.9553959965705872 0.9553959965705872 0.956179976463318 0.9475290179252625 0.0623021200299263 0.0623021200299263 0.0 0.0 53.28238567002296 50.0 0.0 no 14392 chrXVI_92154r 35405 essential YPL242C 2933 + CCTATGGCACGCGATTGAAA L|979|V silent|CTA>TTA|L|979 IQG1 IQGAP-related protein 1495.0 0 0 0 0 0.05931985142715322 Q12280 0.9512209892272948 0.4191366136074066 47.459427349879654 50.0 0.0 no 14393 chrXVI_92220r 35407 essential YPL242C 2867 + TCCTCAGCATTGTTCGCCTG P|957|R P|957|L P|957|A P|957|S IQG1 IQGAP-related protein 1495.0 0 1 0 0 -0.1835026310914227 Q12280 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.3582749664783478 0.5331599116325378 1.0 0.6124644875526428 57.92396985282096 55.00000000000001 0.0 no 14394 chrXVI_92282 35408 essential YPL242C 2808 - TCACTTTCAAAATCCACTAC S|942|T S|942|N D|943|H D|943|N IQG1 IQGAP-related protein 1495.0 0 0 0 0 -0.37664094838609263 Q12280 0.9512869715690612 0.9536849856376648 0.9486550092697144 0.956179976463318 0.08125247061252594 0.15063785016536713 0.015276496298611162 0.2917719185352325 40.5135934059764 35.0 0.0 no 14395 chrXVI_92319r 35411 essential YPL242C 2768 + CTCTATAATAGTCCCAGTTT S|924|C S|924|F IQG1 IQGAP-related protein 1495.0 0 0 0 0 0.06606374535091641 Q12280 0.945252001285553 0.9294660091400146 0.02050226181745529 0.021576836705207825 46.405050756197966 35.0 0.0 no 14396 chrXVI_92330 35412 essential YPL242C 2760 - ACTATTATAGAGAAGAATTC V|927|L V|927|I IQG1 IQGAP-related protein 1495.0 0 0 0 0 -0.17152483658371026 Q12280 0.9539830088615416 0.9574310183525084 0.5970444679260254 0.4580816626548767 32.0124301844362 25.0 0.0 no 14397 chrXVI_92566 35414 essential YPL242C 2524 - ATACAGCAATTTCCAATAAG silent|CTG>CTC|L|847 silent|CTG>CTA|L|847 L|846|F silent|TTG>TTA|L|846 IQG1 IQGAP-related protein 1495.0 0 0 0 0 0.28841645411261085 Q12280 0.9587849974632264 0.1481330692768097 37.49820705075018 30.0 0.0 no 14398 chrXVI_92534 35415 essential YPL242C 2556 - ACATTCTTTGCAACAAATTC V|859|L V|859|I K|857|N silent|AAG>AAA|K|857 IQG1 IQGAP-related protein 1495.0 0 0 0 0 0.4715482777023042 Q12280 0.9539830088615416 0.9574310183525084 0.9355990290641784 0.11206137388944626 1.0 0.3756270110607147 38.198393226560476 30.0 0.0 no 14399 chrXVI_92578r 35416 essential YPL242C 2509 + TGCAAGTTGATCCCTCTTAT Q|838|E Q|838|* IQG1 IQGAP-related protein 1495.0 0 0 0 0 -0.5772686994065971 Q12280 0.9590039849281312 0.0 49.767813604131156 40.0 0.0 no 14400 chrXVI_92781 35422 essential YPL242C 2309 - AGGCTTGGCAACTCTCCAAC A|776|P A|776|T IQG1 IQGAP-related protein 1495.0 0 0 0 0 0.2260213780308565 Q12280 0.9573720097541808 0.9523990154266356 0.0 0.0 53.33773501182088 55.00000000000001 0.0 no 14401 chrXVI_92787 35423 essential YPL242C 2303 - GGCAACTCTCCAACTGGTTT C|774|S C|774|Y S|773|T S|773|N IQG1 IQGAP-related protein 1495.0 0 0 0 0 -0.9421046324719828 Q12280 0.9421560168266296 0.9290120005607604 0.9512869715690612 0.9536849856376648 0.6035126447677612 1.0 0.4293615520000458 0.18684791028499606 52.45125878414411 50.0 0.0 no 14402 chrXVI_92863r 35425 essential YPL242C 2224 + ACTGTCCAAATCCAAGTCTT D|742|E silent|GAC>GAT|D|742 P|744|A P|744|S IQG1 IQGAP-related protein 1495.0 0 0 0 0 -0.11099371891183923 Q12280 0.9532920122146606 0.9562489986419678 0.9498909711837769 1.0 0.18006780743598938 0.04158325865864754 47.327629344031884 40.0 0.0 no 14403 chrXVI_92895r 35426 essential YPL242C 2192 + TCTGCAAAGATCGGCATATT L|732|V silent|CTG>TTG|L|732 Q|733|E Q|733|* IQG1 IQGAP-related protein 1495.0 0 0 0 0 1.0471818328705809 Q12280 0.9512209892272948 0.9590039849281312 0.4047874212265015 0.06395190954208374 44.48983759535344 40.0 0.0 no 14404 chrXVI_93230r 35432 essential YPL242C 1857 + GCATCAATAATATATTCACT A|620|G A|620|V S|621|* S|621|L IQG1 IQGAP-related protein 1495.0 0 0 0 0 -0.8819304267298507 Q12280 0.9484469890594482 0.9504740238189696 0.9298099875450134 0.4052235186100006 0.33530986309051514 0.3209832012653351 36.74706062834986 25.0 0.0 no 14405 chrXVI_93309r 35433 essential YPL242C 1778 + TGCTGTACATGATGTACATA A|594|G A|594|V IQG1 IQGAP-related protein 1495.0 0 0 0 0 0.9915527483517198 Q12280 0.9484469890594482 0.9504740238189696 0.3796499967575073 0.2946554720401764 42.732227058829274 35.0 0.0 no 14406 chrXVI_93345r 35435 essential YPL242C 1742 + TAACGTTGTGAGGTGTTCAG N|582|K silent|AAC>AAT|N|582 IQG1 IQGAP-related protein 1495.0 0 0 0 0 -0.5239346431398011 Q12280 0.9439849853515624 0.8909484744071959 45.494493972755954 45.0 0.0 no 14407 chrXVI_93408 35436 essential YPL242C 1682 - CATCGTTCAACTTTGTATTG D|567|H D|567|N IQG1 IQGAP-related protein 1495.0 0 0 0 0 0.3735071248919236 Q12280 0.9486550092697144 0.956179976463318 0.14154301583766934 0.4955813586711884 41.31252471244261 35.0 0.0 no 14408 chrXVI_93409 35438 essential YPL242C 1681 - ATCGTTCAACTTTGTATTGA D|567|H D|567|N L|565|F silent|TTG>TTA|L|565 IQG1 IQGAP-related protein 1495.0 0 0 0 0 0.23628425086274105 Q12280 0.9486550092697144 0.956179976463318 0.9587849974632264 0.14154301583766934 0.4955813586711884 0.19797469675540924 41.17253770501554 30.0 0.0 no 14409 chrXVI_93508 35439 essential YPL242C 1582 - ATCATTTAATTTTGTGTTAA D|534|H D|534|N IQG1 IQGAP-related protein 1495.0 0 0 0 0 0.33448101764201993 Q12280 0.9486550092697144 0.956179976463318 0.5715942978858948 0.9051254391670228 33.81925804921991 15.0 0.0 no 14410 chrXVI_93720 35442 essential YPL242C 1370 - CTCTAAATTTATTTCCTCTT R|463|T R|463|K IQG1 IQGAP-related protein 1495.0 0 0 0 0 0.2989101280412596 Q12280 0.932735025882721 0.955805003643036 0.0 0.0 40.40137294213662 25.0 0.0 no 14411 chrXVI_93824r 35443 essential YPL242C 1263 + CAACTGCAAAATATTTGTCG L|423|V silent|CTG>TTG|L|423 Q|424|E Q|424|* IQG1 IQGAP-related protein 1495.0 0 0 0 0 0.8053687408049137 Q12280 0.9512209892272948 0.9590039849281312 0.3386363983154297 0.0 37.19226666791127 35.0 0.0 no 14412 chrXVI_93880r 35444 essential YPL242C 1207 + ATTCTCCCATGAGAAGAGAA S|404|C S|404|F P|405|A P|405|S IQG1 IQGAP-related protein 1495.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.4363964859488719 Q12280 0.945252001285553 0.9294660091400146 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 44.24678562348771 40.0 0.0 no 14413 chrXVI_93964r 35445 essential YPL242C 1123 + ATACAGAATTTTATACGAGA T|376|R T|376|I IQG1 IQGAP-related protein 1495.0 0 0 0 0 0.4230896582710051 Q12280 0.9476869702339172 0.9472420215606691 0.007185347378253938 0.007953419350087644 34.45271947418473 25.0 0.0 no 14414 chrXVI_94125r 35449 essential YPL242C 962 + AGCTCCAAAAATGTCAAATT A|322|G A|322|V P|323|A P|323|S IQG1 IQGAP-related protein 1495.0 0 1 0 0 0.4850149382656099 Q12280 0.9484469890594482 0.9504740238189696 0.9562489986419678 0.9498909711837769 0.3801265060901642 0.3791009485721588 0.8168193101882935 0.7762340307235718 37.58389524966333 30.0 0.0 no 14415 chrXVI_94190 35450 essential YPL242C 900 - GCATCTGTTATATTCTTTCT A|307|P A|307|T D|306|H D|306|N IQG1 IQGAP-related protein 1495.0 0 1 0 0 -0.010439809181360712 Q12280 0.9573720097541808 0.9523990154266356 0.9486550092697144 0.956179976463318 0.28227901458740234 0.5886399149894714 0.11448971182107925 0.4466152191162109 45.08768404910421 30.0 0.0 no 14416 chrXVI_94299r 35451 essential YPL242C 788 + TACTGCACCAGCTTCCCCTG T|264|S T|264|I A|265|G A|265|V IQG1 IQGAP-related protein 1495.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.10926205513178466 Q12280 0.9491789937019348 0.9472420215606691 0.9484469890594482 0.9504740238189696 0.8634903430938721 0.26403746008872986 0.26389941573143005 1.0 61.13491804756711 60.0 0.0 no 14417 chrXVI_94375 35454 essential YPL242C 715 - ACAAGCTGCGATTTCTTCTT C|245|S C|245|Y A|244|P A|244|T IQG1 IQGAP-related protein 1495.0 0 0 0 0 0.054176556695805206 Q12280 0.9421560168266296 0.9290120005607604 0.9573720097541808 0.9523990154266356 0.019296059384942055 0.005427817348390818 0.16200754046440125 0.39542970061302185 47.739618052777814 40.0 0.0 no 14418 chrXVI_94622r 35461 essential YPL242C 465 + ACAACGGTTATATTTCCTGC T|156|R T|156|I T|157|R T|157|M IQG1 IQGAP-related protein 1495.0 0 0 0 0 1.2354763536569129 Q12280 0.9476869702339172 0.9472420215606691 0.9476869702339172 0.9502379894256592 0.04055982083082199 0.560872495174408 0.4346930682659149 0.044007156044244766 45.98390140356275 40.0 0.0 no 14419 chrXVI_94644 35462 essential YPL242C 446 - TCAAATCTGGATTTATCCTC L|155|F silent|TTG>TTA|L|155 D|154|H D|154|N IQG1 IQGAP-related protein 1495.0 0 0 0 0 -0.07539591701308013 Q12280 0.9587849974632264 0.9486550092697144 0.956179976463318 0.0 0.060255061835050576 0.4376861751079559 42.45973758946553 35.0 0.0 no 14420 chrXVI_94706r 35463 essential YPL242C 381 + TCAGAAATAGAGTTATGTGT S|128|* S|128|L IQG1 IQGAP-related protein 1495.0 0 0 0 0 -1.4586621976922582 Q12280 0.9298099875450134 0.10744393616914748 37.46867128627639 30.0 0.0 no 14421 chrXVI_94846 35464 essential YPL242C 244 - TCCTACGAGTTTGTTAGGAA G|88|R G|88|R G|88|A G|88|E IQG1 IQGAP-related protein 1495.0 0 0 0 0 -0.4305674497777793 Q12280 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.5533130764961243 0.5533130764961243 0.7981364130973816 1.0 45.69336651654379 40.0 0.0 no 14422 chrXVI_94940 35466 essential YPL242C 150 - GTCTTAGTCTTTAAATGACT K|56|N silent|AAG>AAA|K|56 IQG1 IQGAP-related protein 1495.0 0 1 0 0 0.5986014934479462 Q12280 0.9355990290641784 0.014476327225565909 39.787660077578266 30.0 0.0 no 14423 chrXVI_95008 35467 essential YPL242C 82 - TCTCAGAGGTGGAGTCACAT silent|CTG>CTC|L|33 silent|CTG>CTA|L|33 R|34|T R|34|K IQG1 IQGAP-related protein 1495.0 0 0 0 1 -6.862851928612143 Q12280 0.932735025882721 0.955805003643036 0.19691768288612368 1.0 51.51350223127139 50.0 0.0 yes 14424 chrXVI_95033r 35468 essential YPL242C 54 + AATCGTTATGTTGAAAACCT R|20|G R|20|C IQG1 IQGAP-related protein 1495.0 0 0 0 0 -0.3811920328208345 Q12280 0.8994590044021606 0.8926740288734436 0.0 0.0 38.28466386804666 30.0 0.0 no 14425 chrXVI_100503r 35471 essential YPL237W 10 - TCCTAACTCAGCAGCTAAAT G|10|R G|10|R G|10|A G|10|E SUI3 SUppressor of Initiator codon 285.0 0 0 0 0 -1.271526194360811 P09064 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 45.29896334765374 40.0 1.0 no 14426 chrXVI_100531r 35472 essential YPL237W 38 - TCTTTTTCTTCTTTAGTGCA K|19|N silent|AAG>AAA|K|19 SUI3 SUppressor of Initiator codon 285.0 0 1 0 0 0.6553491842742929 P09064 0.9355990290641784 0.010064997710287573 46.68744191962588 30.0 1.0 no 14427 chrXVI_100532r 35473 essential YPL237W 39 - TTCTTTTTCTTCTTTAGTGC K|19|N silent|AAG>AAA|K|19 SUI3 SUppressor of Initiator codon 285.0 0 1 0 0 0.2257087969773571 P09064 0.9355990290641784 0.010064997710287573 45.518117029777564 30.0 1.0 no 14428 chrXVI_100674r 35476 essential YPL237W 181 - CTCTTTTTCAGCTTCAGCAT E|67|Q E|67|K SUI3 SUppressor of Initiator codon 285.0 0 1 0 0 -0.7125619144766479 P09064 0.956179976463318 0.9475290179252625 0.31948840618133545 0.5961505770683289 50.845019583583394 40.0 1.0 no 14429 chrXVI_100697r 35478 essential YPL237W 204 - GCTTCTGCTATGTCGTCAGT A|75|P A|75|T E|74|Q E|74|K SUI3 SUppressor of Initiator codon 285.0 0 0 0 0 -0.5866630893868816 P09064 0.9573720097541808 0.9523990154266356 0.956179976463318 0.9475290179252625 0.22293350100517276 0.4714765250682831 0.5840044021606445 0.9165615439414978 55.89997715331856 50.0 1.0 no 14430 chrXVI_100719r 35480 essential YPL237W 226 - CTTCAAGGATAGTTCACCCA L|81|F silent|TTG>TTA|L|81 SUI3 SUppressor of Initiator codon 285.0 0 1 0 0 -0.1557037971684389 P09064 0.9587849974632264 0.4048528671264648 49.79655556646924 45.0 1.0 no 14431 chrXVI_100856 35481 essential YPL237W 360 + TCCAGCATTCAACAAGAAGT silent|TCC>TCG|S|121 silent|TCC>TCT|S|121 S|121|C S|121|F SUI3 SUppressor of Initiator codon 285.0 0 0 1 Series([], Name: modification, dtype: object) 0 0.9228888209033426 P09064 0.945252001285553 0.9294660091400146 0.04848038032650948 0.10527238249778748 -0.7978000044822693 1.843000054359436 44.009194611299506 40.0 1.0 no 14432 chrXVI_100934r 35483 essential YPL237W 441 - CTTCTATCACCAGCAAGTTC R|153|T R|153|K SUI3 SUppressor of Initiator codon 285.0 0 1 0 0 -0.3910314737504843 P09064 0.932735025882721 0.955805003643036 0.5690104365348816 1.0 49.00703841829545 45.0 1.0 no 14433 chrXVI_100925 35485 essential YPL237W 429 + ACTAACAATCCAGAACTTGC T|144|S T|144|I N|145|K silent|AAC>AAT|N|145 SUI3 SUppressor of Initiator codon 285.0 0 0 0 0 0.7243170174350972 P09064 0.9491789937019348 0.9472420215606691 0.9439849853515624 0.6747010946273804 0.16325752437114716 1.0 -1.4575999975204468 41.87510194517147 40.0 1.0 no 14434 chrXVI_100982r 35489 essential YPL237W 489 - TTACCATCACGCAAACAAAC G|169|A G|169|D G|169|R G|169|S SUI3 SUppressor of Initiator codon 285.0 0 0 0 0 0.3091533294974189 P09064 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.0 0.0 0.0 0.0 40.24463013837402 40.0 1.0 no 14435 chrXVI_101116 35493 essential YPL237W 620 + TCAGAAAAGATTAGTCATTA Q|208|E Q|208|* SUI3 SUppressor of Initiator codon 285.0 0 0 0 0 0.07861003080549532 P09064 0.9590039849281312 0.0683102235198021 33.799268723463804 25.0 1.0 no 14436 chrXVI_103292 35494 essential YPL235W 60 + GCTGCCCACTCCCATATTAC A|21|G A|21|V A|22|G A|22|V RVB2 RuVB-like 471.0 0 0 0 0 0.16329442651514775 Q12464 0.8942509889602661 0.6734219789505005 0.8255149722099304 0.916782021522522 0.9236735105514526 0.02941896393895149 0.05838476121425629 0.1915060877799988 0.6869999766349792 0.6460000276565552 0.4850000143051148 0.29980000853538513 58.721458298050216 55.00000000000001 1.0 no 14437 chrXVI_103298 35495 essential YPL235W 66 + CACTCCCATATTACAGGTTT H|23|Q silent|CAC>CAT|H|23 S|24|C S|24|F RVB2 RuVB-like 471.0 0 0 0 0 -0.6902899006842332 Q12464 0.7522069811820984 0.7205979824066162 0.7003089785575867 0.004109066911041737 0.0016295586246997118 0.0008264868520200253 -0.03840000182390213 49.229765739589205 40.0 1.0 no 14438 chrXVI_103337 35496 essential YPL235W 105 + CAACCACGTCCCACATCCGA P|37|A P|37|S P|37|R P|37|L RVB2 RuVB-like 471.0 0 0 0 0 0.3316745696134725 Q12464 0.9651510119438172 0.8855559825897217 0.7489399909973145 0.8646690249443054 1.0 0.04654403403401375 0.025185847654938698 0.3218097686767578 56.126106641641464 60.0 1.0 no 14439 chrXVI_103342 35498 essential YPL235W 110 + ACGTCCCACATCCGAAGGTA R|38|G R|38|C P|39|A P|39|S RVB2 RuVB-like 471.0 0 0 0 0 -0.3076811322042514 Q12464 0.8899139761924744 0.7585650086402893 1.0204000473022459 1.0113099813461304 0.32814139127731323 0.05267719179391861 0.770625114440918 0.7274544239044191 54.502176558043395 55.00000000000001 1.0 no 14440 chrXVI_103346r 35500 essential YPL235W 117 - CCAACCATACCTTCGGATGT G|46|R G|46|R V|45|L V|45|I RVB2 RuVB-like 471.0 0 0 0 0 -0.1852621757045816 Q12464 0.5753939747810364 0.5753939747810364 0.8611069917678833 0.9043580293655396 0.003259957768023014 0.003259957768023014 0.04685932770371437 0.15810176730155945 -0.578000009059906 -0.5382000207901001 51.946435180290784 50.0 1.0 no 14441 chrXVI_103380r 35502 essential YPL235W 151 - TATCACACCAGCAGCACGAC silent|GTG>GTC|V|56 silent|GTG>GTA|V|56 V|56|L V|56|M RVB2 RuVB-like 471.0 0 0 0 0 -0.013301566448915114 Q12464 0.9346489906311036 0.8757259845733643 0.3182103633880615 0.06933199614286423 -0.4794000089168549 -0.8428000211715698 -1.693600058555603 -1.926800012588501 51.49031413788617 55.00000000000001 1.0 no 14442 chrXVI_103412 35503 essential YPL235W 180 + GTTCAAAATGGCACCATAGC Q|62|E Q|62|* RVB2 RuVB-like 471.0 0 0 0 0 -0.6072716562372796 Q12464 1.0165799856185913 0.15600642561912534 45.79972048677104 45.0 1.0 no 14443 chrXVI_103459r 35506 essential YPL235W 230 - GAGCGGTCTTACCAGTTGAA A|83|P A|83|T RVB2 RuVB-like 471.0 0 0 0 0 -5.1435606255516575 Q12464 0.628013014793396 0.6697450280189514 0.0 0.0 50.96860938407565 50.0 1.0 yes 14444 chrXVI_103517 35509 essential YPL235W 285 + GTACCATTCACTGCTATTGC P|97|A P|97|S P|97|R P|97|L RVB2 RuVB-like 471.0 0 0 0 0 -0.0987159115909546 Q12464 0.6844220161437988 0.6767110228538513 0.6704400181770325 0.6381419897079468 0.006861170288175345 0.00619435403496027 0.055195380002260215 0.004330397117882967 50.65838392496829 45.0 1.0 no 14445 chrXVI_103705 35511 essential YPL235W 473 + GACTATTAAAACTACCGATA T|159|S T|159|I RVB2 RuVB-like 471.0 0 0 0 0 0.3386140107174546 Q12464 0.9649980068206788 0.931513011455536 0.6461657285690308 0.08374453336000443 36.17470850008203 30.0 1.0 no 14446 chrXVI_103769 35512 essential YPL235W 537 + ACTAAAGAAAAGGTATTGGC T|180|S T|180|I RVB2 RuVB-like 471.0 0 0 0 0 0.8381988832136456 Q12464 0.9869369864463806 0.9866260290145874 0.7435875535011292 0.21122856438159945 35.938260151465784 35.0 1.0 no 14447 chrXVI_104044r 35519 essential YPL235W 815 - CTGCCACTTTTGTGTTTATC A|278|P A|278|T silent|GTG>GTC|V|277 silent|GTG>GTA|V|277 RVB2 RuVB-like 471.0 0 0 0 0 1.1557680643379409 Q12464 0.945963978767395 0.9555420279502868 0.27524375915527344 0.6003462672233582 2.9242000579833984 0.7134000062942505 49.138533445721066 40.0 1.0 no 14448 chrXVI_104099r 35520 essential YPL235W 870 - TCGTCGATAAATAATACACC E|297|Q E|297|K D|296|H D|296|N RVB2 RuVB-like 471.0 0 0 0 0 -3.899212633661669 Q12464 0.6033669710159302 0.5143100023269653 0.6790810227394104 0.7229040265083313 0.0 0.0 0.0 0.0 38.01301709959057 35.0 1.0 yes 14449 chrXVI_104113 35521 essential YPL235W 881 + TATCGACGAAGTCCACATGT I|295|M silent|ATC>ATT|I|295 D|296|E silent|GAC>GAT|D|296 RVB2 RuVB-like 471.0 0 0 0 0 0.9449769161376212 Q12464 0.6729900240898132 0.7213569879531859 0.0014872190076857805 0.0 46.35624704736847 45.0 1.0 no 14450 chrXVI_104192 35523 essential YPL235W 960 + GTCATGATGGCTACAAATAG silent|GTC>GTG|V|321 silent|GTC>GTT|V|321 RVB2 RuVB-like 471.0 0 0 0 0 -0.06636668606125595 Q12464 40.8164559715853 40.0 1.0 no 14451 chrXVI_104234 35524 essential YPL235W 1002 + ACTAATTACAAATCTCCACA T|335|S T|335|I RVB2 RuVB-like 471.0 0 0 0 0 0.1538143234681719 Q12464 0.7879769802093506 0.6333680152893066 0.14916974306106567 0.023460064083337784 -0.2948000133037567 2.571799993515014 0.7125999927520752 4.584799766540527 38.909284006480455 30.0 1.0 no 14452 chrXVI_105075 35525 high_effect YPL234C 346 - AACGTCACCGACCATACCAA V|122|L V|122|I D|121|H D|121|N 0 0 0 0 -0.1294119890256359 P32842 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 0.1106703355908394 0.1163705438375473 0.0012452637311071155 0.032583381980657584 -1.5369399785995483 -1.5328600406646729 49.29712453711284 50.0 0.0 no 14453 chrXVI_105315 35529 high_effect YPL234C 106 - ACCTGACTTAGCTGTACCAA G|42|R G|42|S G|42|A G|42|D 0 0 0 0 -1.910789989267094 P32842 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.001019150367937982 0.12539950013160706 0.11573398113250732 0.00118655851110816 50.00131818283136 45.0 0.0 no 14454 chrXVI_105316r 35530 high_effect YPL234C 102 + GCCATTGGTACAGCTAAGTC silent|GCC>GCG|A|35 silent|GCC>GCT|A|35 A|35|G A|35|V 0 0 0 0 -0.9144970590793032 P32842 0.9484469890594482 0.9504740238189696 0.028478903695940968 0.02147270925343037 1.0221999883651731 0.28189998865127563 51.78493745791018 50.0 0.0 no 14455 chrXVI_105343r 35533 high_effect YPL234C 75 + GCCATGGTGCTTTCCTGTTT silent|GCC>GCG|A|26 silent|GCC>GCT|A|26 A|26|G A|26|V 0 0 0 0 -0.5574304543008766 P32842 0.9484469890594482 0.9504740238189696 0.09174498915672302 0.0036614432465285054 1.9043999910354612 1.467640042304993 59.287587422878005 50.0 0.0 no 14456 chrXVI_105376r 35537 high_effect YPL234C 42 + GCTCCCTTTTTCGGGTTCGC P|16|A P|16|S A|15|G A|15|V 0 0 0 0 -0.11783779301567765 P32842 0.9562489986419678 0.9498909711837769 0.9484469890594482 0.9504740238189696 0.15023021399974826 0.32091549038887024 0.0817529559135437 0.031041886657476425 -4.912559986114502 15.706780433654785 61.88328076461403 60.0 0.0 no 14457 chrXVI_105372 35538 high_effect YPL234C 49 - ACAACCTGCGAACCCGAAAA C|23|S C|23|Y G|22|A G|22|D 0 0 0 0 -1.1576757514894698 P32842 0.9421560168266296 0.9290120005607604 0.9499930143356324 0.9446240067481996 0.048880357295274734 0.014230608008801937 0.0 0.0 45.8266857321421 50.0 0.0 no 14458 chrXVI_106177 35540 essential YPL233W 5 + ACAAGGTCAGTCCAAAAAAC Q|3|E Q|3|* NSL1 Nnf1 Synthetic Lethal 216.0 0 1 0 0 0.022303127381915828 Q12143 38.81704137707186 40.0 1.0 no 14459 chrXVI_106277r 35542 essential YPL233W 108 - TCATCGTCGTATTCTTTCTT D|43|H D|43|N D|42|H D|42|N NSL1 Nnf1 Synthetic Lethal 216.0 0 1 0 0 -1.0801608064444934 Q12143 0.0 0.0 0.07054364681243896 0.6940467357635498 47.22919169709132 35.0 1.0 no 14460 chrXVI_106339 35543 essential YPL233W 167 + TCTTTTGAGCGCTATGACGA L|57|V L|57|F NSL1 Nnf1 Synthetic Lethal 216.0 0 0 0 0 0.3879601083105985 Q12143 0.2434139996767044 0.03625357896089554 47.860672541495326 45.0 1.0 no 14461 chrXVI_106452r 35546 essential YPL233W 283 - CTCATTCAGGTCAAGGTCAA E|101|Q E|101|K silent|CTG>CTC|L|99 silent|CTG>CTA|L|99 NSL1 Nnf1 Synthetic Lethal 216.0 0 0 0 0 -0.10965503987174292 Q12143 0.0 0.0 47.57023149524429 45.0 1.0 no 14462 chrXVI_106465r 35548 essential YPL233W 296 - TCTTTCTAACTTGCTCATTC K|105|N silent|AAG>AAA|K|105 R|104|T R|104|K NSL1 Nnf1 Synthetic Lethal 216.0 0 0 0 0 0.5507892442096477 Q12143 0.30230724811553955 0.0 0.0 44.82700438097902 35.0 1.0 no 14463 chrXVI_106570 35552 essential YPL233W 398 + CAACTCAAAGGATGAGTATT N|134|K silent|AAC>AAT|N|134 S|135|* S|135|L NSL1 Nnf1 Synthetic Lethal 216.0 0 0 0 0 -0.1515325217986829 Q12143 0.8897179365158081 0.113484688103199 37.90758321475124 35.0 1.0 no 14464 chrXVI_108719r 35554 essential YPL231W 70 - TTCAATCCATCTCACAGGAG E|30|Q E|30|K W|28|C W|28|* FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 -0.5528574140336717 P19097 0.2730463445186615 0.16232694685459134 0.0 47.04007611888585 45.0 1.0 no 14465 chrXVI_108789 35555 essential YPL231W 137 + AATCGGTCCTTCTCCAACTT I|47|M silent|ATC>ATT|I|47 FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 -0.1329204508303289 P19097 0.061280731111764915 51.502536413522996 45.0 1.0 no 14466 chrXVI_108793 35556 essential YPL231W 141 + GGTCCTTCTCCAACTTTGGC P|49|A P|49|S P|49|R P|49|L FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 0.8873649814662659 P19097 0.0 0.0 0.0 0.0 57.79825570378085 55.00000000000001 1.0 no 14467 chrXVI_108798 35557 essential YPL231W 146 + TTCTCCAACTTTGGCTGGGA S|50|C S|50|F P|51|A P|51|S FAS2 Fatty Acid Synthetase 1887.0 1 Series([], Name: modification, dtype: object) 0 0 0 1.0090946521090376 P19097 0.06395328044891357 0.030244844034314163 0.05888959765434265 0.16711919009685516 53.636585492708775 50.0 1.0 no 14468 chrXVI_108930 35560 essential YPL231W 278 + TCCATCCGAACTAGCTGCAA P|94|R P|94|L P|94|A P|94|S FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 -0.95323245628704 P19097 0.4418947994709015 0.2568557560443878 0.7171183824539185 0.6255399584770203 51.28517827950486 50.0 1.0 no 14469 chrXVI_108935r 35561 essential YPL231W 286 - CTCTTCCTTTGCAGCTAGTT E|102|Q E|102|K E|101|Q E|101|K FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 -0.1360234713766249 P19097 0.5516113638877869 0.7231163382530212 0.2232634127140045 0.2117656916379929 54.94819166505556 45.0 1.0 no 14470 chrXVI_109150r 35574 essential YPL231W 501 - TCTTTGATTGTCTTGGACAT D|174|H D|174|N FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 0.1743009091738339 P19097 0.004533714149147272 0.012027161195874214 0.1993999928236008 0.3847799897193909 44.971907286112526 35.0 1.0 no 14471 chrXVI_109162 35575 essential YPL231W 510 + ACAATCAAAGACTTGGTCGG T|171|R T|171|I I|172|M silent|ATC>ATT|I|172 FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 -0.2357980435041513 P19097 0.012556803412735462 0.01341847609728575 0.002999225398525596 -0.5220000147819519 -0.6678599715232849 -0.5610399842262268 42.189239339257604 45.0 1.0 no 14472 chrXVI_109285 35576 essential YPL231W 633 + ACTTTCCAAGATACCTTCTC T|212|S T|212|I F|213|L silent|TTC>TTT|F|213 FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 -1.1759498728189182 P19097 0.4070281684398651 0.1035609245300293 1.0 -0.3478800058364868 -0.6726400256156921 0.9397199749946594 47.560143067786896 40.0 1.0 no 14473 chrXVI_109417 35581 essential YPL231W 765 + CTACCATCTGGTAGACAAGA P|257|A P|257|S P|257|R P|257|L FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 -2.2367381764827905 P19097 0.4983465373516083 0.29491180181503296 0.07648133486509323 0.056409824639558785 2.333940029144287 2.100600004196167 2.123800039291382 2.381419897079468 46.04216907279897 45.0 1.0 yes 14474 chrXVI_109420r 35582 essential YPL231W 771 - ACACCATCTTGTCTACCAGA G|263|A G|263|D V|264|L V|264|I FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 -0.8764819067277365 P19097 0.6969804763793945 0.09766246378421783 0.21199849247932434 0.2138870507478714 1.8437000513076784 8.79185962677002 0.6385200023651123 -0.6736800074577332 51.425953046907644 45.0 1.0 no 14475 chrXVI_109755 35591 essential YPL231W 1103 + TGCTGAACTTCAAGCTCAGT A|369|G A|369|V FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 0.7207078155231357 P19097 0.3677628338336945 0.2804107964038849 48.20302561805625 45.0 1.0 no 14476 chrXVI_109824 35593 essential YPL231W 1172 + TACTTCTTTCTCTAGAAAAA T|392|S T|392|I S|393|C S|393|F FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 0.3530255082005576 P19097 0.2631658315658569 0.017155194655060768 0.08829832077026367 0.11652427166700365 34.92607726281886 25.0 1.0 no 14477 chrXVI_109847 35594 essential YPL231W 1195 + CCAGAACCTTCGATTCTTCC silent|GCC>GCG|A|399 silent|GCC>GCT|A|399 T|401|S T|401|I FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 1.1488831891499025 P19097 0.2987040877342224 0.15771999955177307 51.734541929017155 50.0 1.0 no 14478 chrXVI_109854 35596 essential YPL231W 1202 + CTTCGATTCTTCCTGGAACT F|402|L silent|TTC>TTT|F|402 FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 0.2461743248703615 P19097 0.0288278516381979 48.966196554812434 45.0 1.0 no 14479 chrXVI_109853 35597 essential YPL231W 1201 + CCTTCGATTCTTCCTGGAAC silent|ACC>ACG|T|401 silent|ACC>ACT|T|401 F|402|L silent|TTC>TTT|F|402 FAS2 Fatty Acid Synthetase 1887.0 0 0 0 1 0.7958619936026661 P19097 0.0288278516381979 50.85777783706908 50.0 1.0 no 14480 chrXVI_110047 35599 essential YPL231W 1395 + TATCAATTGGTTAAAACTCT Q|467|E Q|467|* FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 0.7582944001740083 P19097 0.9095181822776794 35.22148434039537 25.0 1.0 no 14481 chrXVI_110146r 35602 essential YPL231W 1497 - TTCTTGTCAATAGCAGTTTT K|505|N silent|AAG>AAA|K|505 FAS2 Fatty Acid Synthetase 1887.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.8043250955496726 P19097 0.39332643151283264 43.60244799969883 30.0 1.0 no 14482 chrXVI_110217 35603 essential YPL231W 1565 + ATCTCAATACGTACAAGAAA S|523|C S|523|F Q|524|E Q|524|* FAS2 Fatty Acid Synthetase 1887.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.0925800377835004 P19097 0.048927735537290566 0.04639532417058945 1.0 35.17922681089948 30.0 1.0 no 14483 chrXVI_110227 35605 essential YPL231W 1575 + GTACAAGAAATGGCCCTTGG Q|527|E Q|527|* FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 -0.5058695217794894 P19097 1.0 47.62957063691886 50.0 1.0 no 14484 chrXVI_110272r 35607 essential YPL231W 1623 - GTCAAATCCTCTTCAATAGT L|547|F silent|TTG>TTA|L|547 FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 0.5187914417994812 P19097 0.0957471951842308 43.48351929759547 35.0 1.0 no 14485 chrXVI_110418 35608 essential YPL231W 1766 + TCCTTCTCAAACAACCCAAT P|590|R P|590|L P|590|A P|590|S FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 -0.3874432078527789 P19097 0.15867500007152555 0.05303516611456871 0.3416444957256317 0.3613981008529663 46.17359909519354 40.0 1.0 no 14486 chrXVI_110422 35609 essential YPL231W 1770 + TCTCAAACAACCCAATTGGC Q|592|E Q|592|* S|591|C S|591|F FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 -0.0690079348655109 P19097 1.0 0.05250876024365425 0.050382234156131744 45.63630881020821 45.0 1.0 no 14487 chrXVI_110427 35610 essential YPL231W 1775 + AACAACCCAATTGGCCGGTA T|593|R T|593|I T|594|S T|594|I FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 0.17260096440496306 P19097 0.5400527715682983 0.2101617008447647 0.8668598532676697 0.19344916939735413 50.70423659472078 50.0 1.0 no 14488 chrXVI_110432r 35611 essential YPL231W 1783 - AACATCCATACCGGCCAATT V|601|L V|601|I D|600|H D|600|N FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 0.6535881020257859 P19097 0.5158151984214783 0.3181129395961761 0.12425827980041505 0.4916918277740479 49.81472011561692 45.0 1.0 no 14489 chrXVI_110441r 35612 essential YPL231W 1792 - AGCATCCTCAACATCCATAC A|604|P A|604|T D|603|H D|603|N FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 0.4545241681743666 P19097 0.27506402134895325 0.5776236653327942 0.12354617565870285 0.5193396210670471 49.40887637220578 45.0 1.0 no 14490 chrXVI_110680 35618 essential YPL231W 2028 + TACGTCTTGATCACTGGTGC Y|677|* silent|TAC>TAT|Y|677 silent|GTC>GTG|V|678 silent|GTC>GTT|V|678 FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 0.3368756401369791 P19097 50.49666472234623 50.0 1.0 no 14491 chrXVI_110674 35619 essential YPL231W 2022 + GACAAATACGTCTTGATCAC D|675|E silent|GAC>GAT|D|675 FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 0.7209715355327894 P19097 0.13583803176879886 39.99570593957913 40.0 1.0 no 14492 chrXVI_110725 35620 essential YPL231W 2073 + GTCTTGCAAGGTTTGTTACA silent|GTC>GTG|V|692 silent|GTC>GTT|V|692 Q|694|E Q|694|* FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 0.3315882663938029 P19097 0.019228264689445496 47.98074139355747 40.0 1.0 no 14493 chrXVI_110728 35621 essential YPL231W 2076 + TTGCAAGGTTTGTTACAAGG Q|694|E Q|694|* FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 -0.3847762334870759 P19097 0.019228264689445496 43.33801098437078 40.0 1.0 no 14494 chrXVI_110771r 35622 essential YPL231W 2122 - AACTTGCTTAGAGAAACGAG V|714|L V|714|I K|712|N silent|AAG>AAA|K|712 FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 0.2273069523914357 P19097 0.042869985103607185 0.03573806956410408 0.13606995344161987 38.3047142245893 40.0 1.0 no 14495 chrXVI_110810r 35623 essential YPL231W 2161 - AGCACCATATTTGGCGTAAA A|727|P A|727|T G|726|A G|726|D FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 0.43528758089116976 P19097 0.01291305385529995 0.13907332718372345 0.0 0.0 45.921986531721295 40.0 1.0 no 14496 chrXVI_110814 35624 essential YPL231W 2162 + TTACGCCAAATATGGTGCTA Y|722|* silent|TAC>TAT|Y|722 A|723|G A|723|V FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 -0.05360554828716213 P19097 0.12240933626890182 0.08982259780168532 45.568744679848464 40.0 1.0 no 14497 chrXVI_110815 35625 essential YPL231W 2163 + TACGCCAAATATGGTGCTAA Y|722|* silent|TAC>TAT|Y|722 A|723|G A|723|V FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 0.23760019063911506 P19097 0.12240933626890182 0.08982259780168532 43.9292177277606 40.0 1.0 no 14498 chrXVI_110865r 35627 essential YPL231W 2216 - CAACGTCTTGCTTAGAACCT V|745|L V|745|I D|744|H D|744|N FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 -0.2127506727532716 P19097 0.01709197461605072 0.08941776305437088 0.0 0.0 47.1845926371691 45.0 1.0 no 14499 chrXVI_110962 35629 essential YPL231W 2310 + TTCGCGGCCATTCCAGAACA F|771|L silent|TTC>TTT|F|771 A|772|G A|772|V FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 -0.3818441666585426 P19097 0.0 0.06414831429719925 0.004613575059920549 54.73376718265456 55.00000000000001 1.0 no 14500 chrXVI_110974r 35630 essential YPL231W 2325 - TCTAATTCAATACCTTGTTC E|782|Q E|782|K FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 -0.14044946443936446 P19097 0.15064291656017306 0.21975865960121155 40.506104360553934 30.0 1.0 no 14501 chrXVI_111040 35631 essential YPL231W 2388 + ACCAATATCTTAAGAATGAT silent|ACC>ACG|T|797 silent|ACC>ACT|T|797 T|797|S T|797|I FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 0.6928664027445032 P19097 0.01916247420012951 0.015421000309288503 35.330647241780184 25.0 1.0 no 14502 chrXVI_111138r 35633 essential YPL231W 2489 - CATCACCACCGAAAGTACCA D|836|H D|836|N G|835|A G|835|D FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 -6.76437537823194 P19097 0.003602625336498022 0.01301809027791023 0.1886841356754303 0.1987636238336563 49.196180166415616 50.0 1.0 yes 14503 chrXVI_111168 35635 essential YPL231W 2516 + TTCAGAATCCAAGTTGTCTT S|840|* S|840|L FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 0.7917948680182849 P19097 0.04970650002360344 44.5734049415837 35.0 1.0 no 14504 chrXVI_111226 35638 essential YPL231W 2574 + GCCAATCAATTAACCGTTTG silent|GCC>GCG|A|859 silent|GCC>GCT|A|859 A|859|G A|859|V FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 -0.5057184662165647 P19097 1.0 0.013390767388045788 44.08021878690965 40.0 1.0 no 14505 chrXVI_111402r 35642 essential YPL231W 2753 - CAGCCATAACAGGTGATTTT A|924|P A|924|T M|923|I M|923|I FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 -0.5805072326825247 P19097 0.007362545002251863 0.022100992500782013 0.31459471583366394 0.31459471583366394 46.03744749909481 40.0 1.0 no 14506 chrXVI_111399 35643 essential YPL231W 2747 + GTGCCAAAAATCACCTGTTA C|917|W silent|TGC>TGT|C|917 Q|918|E Q|918|* FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 -1.3218132366751576 P19097 0.0062628937885165215 0.35067737102508545 45.053964123235225 40.0 1.0 no 14507 chrXVI_111412r 35644 essential YPL231W 2763 - CCATTCAAGTCAGCCATAAC G|928|R G|928|S L|926|F silent|TTG>TTA|L|926 FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 0.21113777573649967 P19097 0.0 0.0 0.045847069472074516 47.460745701386315 45.0 1.0 no 14508 chrXVI_111451r 35645 essential YPL231W 2802 - GCAGTGAATTCCTTCAATTC A|941|P A|941|T FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 1.2086400174927103 P19097 0.3013709187507629 0.8657018542289734 45.658496874909076 40.0 1.0 no 14509 chrXVI_111524r 35648 essential YPL231W 2875 - ATGCTCCAAAGCAGTTTCGA E|964|D silent|GAG>GAA|E|964 E|964|Q E|964|K FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 -0.037312109834420376 P19097 1.0 0.08419769257307053 0.012941364198923113 49.21176719380878 45.0 1.0 no 14510 chrXVI_111600 35649 essential YPL231W 2948 + ACCAAGAGCTAACATTCAAC P|984|R P|984|L P|984|A P|984|S FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 -0.4141739008623968 P19097 0.13300234079360962 0.008295086212456226 0.019230147823691368 0.02299170382320881 41.451919857133305 40.0 1.0 no 14511 chrXVI_111667r 35651 essential YPL231W 3018 - AACAAACCTTCAAGCTCAGC L|1012|F silent|TTG>TTA|L|1012 G|1011|A G|1011|D FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 0.32871147128273703 P19097 0.020293209701776505 0.02358251251280308 0.005829794332385063 45.07989372375046 45.0 1.0 no 14512 chrXVI_111771 35653 essential YPL231W 3119 + AGCTTTTGGTGAATTTTCGT A|1041|G A|1041|V FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 0.3039310148405033 P19097 0.029464704915881164 0.06401076167821884 45.67882618031489 35.0 1.0 no 14513 chrXVI_111934 35655 essential YPL231W 3282 + ACATCAATCCTAGAACACAG T|1095|R T|1095|I S|1096|* S|1096|L FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 0.20319037435189186 P19097 0.1693960279226303 0.0579240694642067 0.2862529754638672 41.30071534153944 40.0 1.0 no 14514 chrXVI_111967 35656 essential YPL231W 3315 + ATCGAACCAGAGTTATTCAA I|1106|M silent|ATC>ATT|I|1106 P|1108|A P|1108|S FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 -0.6906205447364582 P19097 0.0034072978887706995 0.07884480059146881 0.014045924879610537 41.456092184239715 35.0 1.0 no 14515 chrXVI_111942r 35657 essential YPL231W 3293 - ATCTGATACCACTGTGTTCT R|1104|T R|1104|K FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 -5.8841815794980565 P19097 0.0 0.0 48.877246251782545 40.0 1.0 yes 14516 chrXVI_112075 35659 essential YPL231W 3423 + GAACAATTTAAACACCAACA Q|1143|E Q|1143|* FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 -0.09990075077651096 P19097 0.5926855206489563 35.15399407545135 30.0 1.0 no 14517 chrXVI_112089r 35661 essential YPL231W 3440 - TATCCACTTTGTCACCATGT D|1153|H D|1153|N silent|GTG>GTC|V|1152 silent|GTG>GTA|V|1152 FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 0.11182641786683856 P19097 0.008509073406457901 0.01572522334754467 50.69108380584356 40.0 1.0 no 14518 chrXVI_112123r 35663 essential YPL231W 3474 - ACAGAGTACTCTCCTGTTTC V|1165|L V|1165|I FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 0.2337168713795204 P19097 0.1160961538553238 0.514412522315979 50.66666064325789 45.0 1.0 no 14519 chrXVI_112137 35664 essential YPL231W 3485 + GTACTCTGTTAAGTTACTAA Y|1163|* silent|TAC>TAT|Y|1163 S|1164|C S|1164|F FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 -0.20668363262436515 P19097 0.2336414605379105 0.969467282295227 39.15177525866818 30.0 1.0 no 14520 chrXVI_112138 35665 essential YPL231W 3486 + TACTCTGTTAAGTTACTAAA Y|1163|* silent|TAC>TAT|Y|1163 S|1164|C S|1164|F FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 -1.1299657124077975 P19097 0.2336414605379105 0.969467282295227 35.33247517712829 25.0 1.0 no 14521 chrXVI_112278 35667 essential YPL231W 3626 + CCCAATCACATTATTCGTTT P|1210|R P|1210|L P|1210|A P|1210|S FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 0.14713556177195855 P19097 0.7165599465370178 0.07457662373781204 0.3498580753803253 0.28602293133735657 45.90105450085144 35.0 1.0 no 14522 chrXVI_112278r 35668 essential YPL231W 3629 - CCAAAACGAATAATGTGATT L|1216|F silent|TTG>TTA|L|1216 V|1215|L V|1215|I FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 0.4431073883655127 P19097 0.008472860790789127 0.1402094066143036 0.19520467519760126 34.80954418223888 30.0 1.0 no 14523 chrXVI_112342r 35670 essential YPL231W 3693 - ACGTATTTGTACATTTCGTA V|1238|L V|1238|I FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 0.5486863176530947 P19097 0.0922950878739357 0.2443214207887649 41.818581963792326 30.0 1.0 no 14524 chrXVI_112384 35672 essential YPL231W 3732 + AACTGTTCTGGTTCTGGTAT N|1245|K silent|AAC>AAT|N|1245 FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 -1.2540641260300929 P19097 0.011380448937416077 48.16876456147617 40.0 1.0 no 14525 chrXVI_112488 35673 essential YPL231W 3836 + TATCAACACCATGTCCGCTT I|1280|M silent|ATC>ATT|I|1280 N|1281|K silent|AAC>AAT|N|1281 FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 -0.3137240979542181 P19097 0.0 0.011573145166039469 50.78295067278077 45.0 1.0 no 14526 chrXVI_112502r 35674 essential YPL231W 3853 - CAACAACATATTAACCCAAG L|1290|F silent|TTG>TTA|L|1290 M|1289|I M|1289|I FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 0.5897698083788112 P19097 0.014667187817394732 0.03239549696445465 0.03239549696445465 37.65832984235272 35.0 1.0 no 14527 chrXVI_112529r 35675 essential YPL231W 3880 - TGTCTTGATTGGACCAGATG K|1299|N silent|AAG>AAA|K|1299 FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 0.2689384006838481 P19097 0.0037075921427458533 46.77498416036542 45.0 1.0 no 14528 chrXVI_112537 35676 essential YPL231W 3885 + GGTCCAATCAAGACACCTGT P|1297|A P|1297|S P|1297|R P|1297|L FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 0.4283800792250808 P19097 0.0 0.0 0.0 0.0 51.08773835957118 50.0 1.0 no 14529 chrXVI_112573 35679 essential YPL231W 3921 + TCCGTGGAATCTGTTGACAT silent|TCC>TCG|S|1308 silent|TCC>TCT|S|1308 S|1308|C S|1308|F FAS2 Fatty Acid Synthetase 1887.0 0 0 0 1 -0.05397966311286702 P19097 0.0035561532713472843 0.0013799021253362296 48.35144595343718 45.0 1.0 no 14530 chrXVI_112656r 35681 essential YPL231W 4007 - ACTCAAAGGAGCCTTCTTCT E|1342|Q E|1342|K E|1342|D silent|GAG>GAA|E|1342 FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 -6.4160254271525385 P19097 0.012128577567636968 0.011233832687139513 0.027336452156305317 50.04470766275017 45.0 1.0 yes 14531 chrXVI_112670r 35682 essential YPL231W 4021 - CTTCATGTTACCGAACTCAA M|1346|I M|1346|I FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 0.7383530857419178 P19097 0.0 0.0 44.101427753971386 40.0 1.0 no 14532 chrXVI_112700r 35684 essential YPL231W 4051 - TTCAAATTCTTCCAAAGTGT E|1357|Q E|1357|K FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 0.5870507610880551 P19097 0.07901156693696976 0.15123674273490906 40.3461237884855 30.0 1.0 no 14533 chrXVI_112761 35689 essential YPL231W 4109 + CACTACCCGTAACGGTTTTA T|1371|S T|1371|I T|1372|S T|1372|I FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 0.9608371770103736 P19097 1.0 0.008388769812881947 0.2568134963512421 0.0028271554037928577 48.53317521402232 45.0 1.0 no 14534 chrXVI_112766r 35690 essential YPL231W 4117 - AGCTTCCATAAAACCGTTAC A|1379|P A|1379|T E|1378|Q E|1378|K FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 -1.1783098917234596 P19097 0.01582401432096958 0.01704820804297924 0.0 0.0 44.26457550744868 40.0 1.0 no 14535 chrXVI_112819 35693 essential YPL231W 4167 + GCTGATTTAGCTTTGAAGAT A|1390|G A|1390|V FAS2 Fatty Acid Synthetase 1887.0 0 0 0 0 0.7658087781366745 P19097 0.0 0.0 42.826935691969474 35.0 1.0 no 14536 chrXVI_112883r 35696 essential YPL231W 4234 - CACAGATCTACCAATCTTAT V|1418|L V|1418|M FAS2 Fatty Acid Synthetase 1887.0 0 1 0 0 0.011487551806633968 P19097 0.08404989540576935 0.0042933174408972255 42.421704059403964 35.0 1.0 no 14537 chrXVI_112899 35697 essential YPL231W 4247 + ATCTGTGCCAGCTCCAGGTA S|1417|C S|1417|F FAS2 Fatty Acid Synthetase 1887.0 1 Series([], Name: modification, dtype: object) 0 0 0 -2.2015467805247138 P19097 0.0 0.0 60.46000046775254 55.00000000000001 1.0 yes 14538 chrXVI_112900 35698 essential YPL231W 4248 + TCTGTGCCAGCTCCAGGTAA S|1417|C S|1417|F P|1419|A P|1419|S FAS2 Fatty Acid Synthetase 1887.0 1 Series([], Name: modification, dtype: object) 0 0 0 -0.8895437307007033 P19097 0.0 0.0 0.0 0.0 58.47531195633599 55.00000000000001 1.0 no 14539 chrXVI_118558 35700 essential YPL228W 176 + TGCTCCGATTGACAATTACA A|60|G A|60|V P|61|A P|61|S CET1 Capping Enzyme Triphosphatase 549.0 0 0 0 0 0.11294329797865292 O13297 0.3843811452388763 0.20004980266094208 0.09236478805541992 0.26676034927368164 45.08764947032563 40.0 1.0 no 14540 chrXVI_118562r 35701 essential YPL228W 183 - CTCTCCTTGTAATTGTCAAT E|67|D silent|GAG>GAA|E|67 E|67|Q E|67|K CET1 Capping Enzyme Triphosphatase 549.0 0 0 0 0 -0.2712600156983393 O13297 44.745141041935256 35.0 1.0 no 14541 chrXVI_118754r 35705 essential YPL228W 375 - TCACTACCATCATTCATAGG S|131|T S|131|N D|132|H D|132|N CET1 Capping Enzyme Triphosphatase 549.0 0 0 0 0 -0.2499054084854085 O13297 0.5556548833847046 0.4861299395561218 0.15319910645484924 0.501026451587677 45.614624442450925 40.0 1.0 no 14542 chrXVI_118757r 35706 essential YPL228W 378 - GCATCACTACCATCATTCAT A|133|P A|133|T D|132|H D|132|N CET1 Capping Enzyme Triphosphatase 549.0 0 0 0 0 -0.4086404192067069 O13297 0.3243579566478729 0.7058471441268921 0.15319910645484924 0.501026451587677 48.71136836826213 40.0 1.0 no 14543 chrXVI_118779r 35707 essential YPL228W 400 - AGGCTTTTCTAACTTCGCAT K|139|N silent|AAG>AAA|K|139 CET1 Capping Enzyme Triphosphatase 549.0 0 0 0 0 0.5259162717183385 O13297 0.4856371879577637 48.403194691095344 40.0 1.0 no 14544 chrXVI_118881r 35710 essential YPL228W 502 - TACTTGGGTTATATAGTTGC V|174|L V|174|I CET1 Capping Enzyme Triphosphatase 549.0 0 0 0 0 0.11945318634596258 O13297 0.2615190148353577 0.22733420133590695 43.52765079783421 35.0 1.0 no 14545 chrXVI_119085 35713 essential YPL228W 703 + CTTCCAAGCCCAGTAAGTAC S|236|C S|236|F silent|TCC>TCG|S|236 silent|TCC>TCT|S|236 CET1 Capping Enzyme Triphosphatase 549.0 0 1 0 0 -0.2590296497994905 O13297 0.01962800696492195 0.01393224112689495 51.55522330070676 50.0 1.0 no 14546 chrXVI_119101 35715 essential YPL228W 719 + GTACAGGAATGTTCCAATTT Y|241|* silent|TAC>TAT|Y|241 CET1 Capping Enzyme Triphosphatase 549.0 0 1 0 0 -3.972911888610735 O13297 43.01782422862465 35.0 1.0 yes 14547 chrXVI_119210r 35716 essential YPL228W 831 - GACTTTGTTAAGTCATCATC K|283|N silent|AAG>AAA|K|283 CET1 Capping Enzyme Triphosphatase 549.0 0 0 0 0 0.8330554033728845 O13297 0.028698399662971493 1.1291199922561646 0.7296000123023987 41.87454225427689 35.0 1.0 no 14548 chrXVI_119218 35718 essential YPL228W 836 + TGACTTAACAAAGTCAGTAC D|280|E silent|GAC>GAT|D|280 CET1 Capping Enzyme Triphosphatase 549.0 0 0 0 0 -1.4726266674640769 O13297 0.0 -0.8755599856376648 1.688599944114685 36.982430464410406 35.0 1.0 no 14549 chrXVI_119223 35719 essential YPL228W 841 + TAACAAAGTCAGTACAGGAC T|282|R T|282|I CET1 Capping Enzyme Triphosphatase 549.0 0 0 0 0 0.3980033527548701 O13297 0.009462327696383001 0.04762910678982735 0.9302200078964232 -0.2353399991989136 38.67299449097652 40.0 1.0 no 14550 chrXVI_119273r 35721 essential YPL228W 894 - TCAATGAAGGATCTTAGTTC E|305|Q E|305|K CET1 Capping Enzyme Triphosphatase 549.0 0 0 0 0 -3.3922549556321764 O13297 0.0 0.0 2.631239891052246 1.9822399616241453 39.47513560432702 35.0 1.0 yes 14551 chrXVI_119402r 35726 essential YPL228W 1023 - AACAAAGATGCATCAATATT L|347|F silent|TTG>TTA|L|347 CET1 Capping Enzyme Triphosphatase 549.0 0 0 0 0 -1.7070975818575935 O13297 0.2875045835971832 2.188560009002685 1.569759964942932 34.03931426423077 25.0 1.0 no 14552 chrXVI_119529 35727 essential YPL228W 1147 + GACTATCCACGCAAAGACCA L|384|V silent|CTA>TTA|L|384 S|385|C S|385|F CET1 Capping Enzyme Triphosphatase 549.0 0 0 0 0 0.7726328320113942 O13297 0.5561129450798035 0.04312663152813912 0.08841998875141144 0.16021999716758728 0.24143999814987185 0.2100600004196167 48.36496199462982 50.0 1.0 no 14553 chrXVI_119546r 35728 essential YPL228W 1167 - GTACTCATTCTCAAAAACCT S|395|T S|395|N M|394|I M|394|I CET1 Capping Enzyme Triphosphatase 549.0 0 0 0 0 0.009672484996130937 O13297 1.0 0.040366701781749725 0.1091439351439476 0.1091439351439476 0.7818199992179871 0.3997400104999542 4.275740146636963 4.275740146636963 1.95169997215271 1.95169997215271 41.27828322056752 35.0 1.0 no 14554 chrXVI_140524 35731 essential YPL217C 2628 - GCATTACAATATGTGTGTTC A|883|P A|883|T C|881|S C|881|Y BMS1 BMh Sensitive 1183.0 0 0 0 0 -1.281513584377762 Q08965 0.9573720097541808 0.9523990154266356 0.9421560168266296 0.9290120005607604 0.012936428189277649 0.008932655677199364 0.0 0.0 42.25543572623712 35.0 0.0 no 14555 chrXVI_140670 35735 essential YPL217C 2482 - CCAACGATGTCTTCTCAACC W|834|S W|834|* R|833|P R|833|H BMS1 BMh Sensitive 1183.0 0 0 0 0 -2.4598143069714777 Q08965 0.8858469724655151 0.9099509716033936 0.9570810198783876 0.0 0.0 0.0 48.93139629249589 50.0 0.0 yes 14556 chrXVI_140697 35737 essential YPL217C 2455 - GACAATACCGAACTTTATTT V|825|L V|825|I BMS1 BMh Sensitive 1183.0 0 0 0 0 -2.216235993422404 Q08965 0.9539830088615416 0.9574310183525084 0.4699301421642304 0.41101989150047297 38.640603198890005 30.0 0.0 yes 14557 chrXVI_140830 35741 essential YPL217C 2322 - TCGATTCTTTGACGTTGTTC E|781|Q E|781|K R|779|T R|779|K BMS1 BMh Sensitive 1183.0 0 0 0 0 1.0695401422435329 Q08965 0.956179976463318 0.9475290179252625 0.932735025882721 0.955805003643036 0.0 0.0 0.5219133496284485 1.0 45.68758485840237 40.0 0.0 no 14558 chrXVI_140883 35742 essential YPL217C 2269 - TTCTAACTGTTTAGATATCT E|763|Q E|763|K Q|761|H silent|CAG>CAA|Q|761 BMS1 BMh Sensitive 1183.0 0 0 0 0 0.19631556957529256 Q08965 0.956179976463318 0.9475290179252625 0.9570760130882264 0.2340128570795059 0.06928534060716629 0.006476039066910744 38.124547337192496 25.0 0.0 no 14559 chrXVI_140906r 35743 essential YPL217C 2243 + TACATGGTATGAACTACAGA T|749|R T|749|I BMS1 BMh Sensitive 1183.0 0 0 0 0 -1.2432050090294895 Q08965 0.9476869702339172 0.9472420215606691 0.016850437968969345 0.007014705799520016 39.26189269709579 35.0 0.0 no 14560 chrXVI_141059r 35745 essential YPL217C 2090 + TTCATTCACTAATTTTGATG S|698|* S|698|L F|699|L silent|TTC>TTT|F|699 BMS1 BMh Sensitive 1183.0 0 0 0 0 1.4503210067462722 Q08965 0.9298099875450134 0.9387490153312684 0.2810879349708557 0.3137385845184326 36.455684535258456 25.0 0.0 no 14561 chrXVI_141143 35746 essential YPL217C 2009 - TGTCTTCTGCTTGTTCAGAA D|676|H D|676|N E|675|Q E|675|K BMS1 BMh Sensitive 1183.0 0 0 0 0 0.4270782427655511 Q08965 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.11968496441841125 0.4900918304920197 0.2987497448921204 0.5074956417083739 48.498030623147535 40.0 0.0 no 14562 chrXVI_141308r 35748 essential YPL217C 1841 + TTTCGACACTTTCGAAAAAT F|615|L silent|TTC>TTT|F|615 D|616|E silent|GAC>GAT|D|616 BMS1 BMh Sensitive 1183.0 0 0 0 0 0.2677523813373427 Q08965 0.9387490153312684 0.9532920122146606 0.642476499080658 0.6795840263366699 0.6087599992752075 0.8919600248336792 36.22358897104107 30.0 0.0 no 14563 chrXVI_141341 35749 essential YPL217C 1811 - ACTTTTCCAAATCAACTGCA K|610|N silent|AAG>AAA|K|610 E|609|Q E|609|K BMS1 BMh Sensitive 1183.0 0 0 0 0 0.1064753815974159 Q08965 0.9355990290641784 0.956179976463318 0.9475290179252625 0.05497782677412033 0.6321156620979309 0.7795888185501099 0.10937999933958054 -0.3839600086212158 -0.4448600113391876 43.430165069439795 35.0 0.0 no 14564 chrXVI_141649r 35750 essential YPL217C 1500 + TTCAATAATACCGGTGAGCA F|501|L silent|TTC>TTT|F|501 BMS1 BMh Sensitive 1183.0 0 1 0 0 -0.8181443851460192 Q08965 0.9387490153312684 0.3124082088470459 44.316368855149896 40.0 0.0 no 14565 chrXVI_141864 35755 essential YPL217C 1288 - AACATCCATGCCTTCATGAT V|436|L V|436|I D|435|H D|435|N BMS1 BMh Sensitive 1183.0 0 1 0 0 0.2295040885447345 Q08965 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 0.3048692047595978 0.18630583584308624 0.09231816232204436 0.589677095413208 48.50562099092343 40.0 0.0 no 14566 chrXVI_141989 35757 essential YPL217C 1163 - TTTCTCCTTCACCTCTTTCT E|394|Q E|394|K G|393|A G|393|E BMS1 BMh Sensitive 1183.0 0 0 0 0 0.037166952240888895 Q08965 0.956179976463318 0.9475290179252625 0.9499930143356324 0.9438679814338684 0.057209879159927375 0.1431727260351181 0.0 0.0 54.78196189883153 40.0 0.0 no 14567 chrXVI_142074 35759 essential YPL217C 1078 - CATCAACACACCTCCGACAT L|365|F silent|TTG>TTA|L|365 silent|GTG>GTC|V|364 silent|GTG>GTA|V|364 BMS1 BMh Sensitive 1183.0 0 0 0 0 -0.8812585912710782 Q08965 0.9587849974632264 0.08782714605331421 49.48576704354719 50.0 0.0 no 14568 chrXVI_142219 35763 essential YPL217C 933 - TCCAGTTTCTGTTGGTAAAA silent|CTG>CTC|L|317 silent|CTG>CTA|L|317 D|318|H D|318|N BMS1 BMh Sensitive 1183.0 0 0 0 0 0.6892546678500404 Q08965 0.9486550092697144 0.956179976463318 43.84247014904457 35.0 0.0 no 14569 chrXVI_141994 35766 essential YPL217C 1158 - CCTTCACCTCTTTCTTGGCC G|393|R G|393|R E|392|Q E|392|K BMS1 BMh Sensitive 1183.0 0 0 0 0 0.2963882527728761 Q08965 0.941340982913971 0.941340982913971 0.956179976463318 0.9475290179252625 0.0 0.0 0.5629453659057617 0.7417402863502502 60.24750447171698 55.00000000000001 0.0 no 14570 chrXVI_142319r 35771 essential YPL217C 830 + TACTCCTTTGCCTTCTGCTC T|278|S T|278|I P|279|A P|279|S BMS1 BMh Sensitive 1183.0 0 0 0 0 -0.05209063231365163 Q08965 0.9491789937019348 0.9472420215606691 0.9562489986419678 0.9498909711837769 0.23239043354988095 0.16388891637325287 0.09906509518623352 0.2852143943309784 57.678551599554005 50.0 0.0 no 14571 chrXVI_142387 35772 essential YPL217C 765 - CCTTGAGTCTCTATTAATTC G|262|R G|262|R BMS1 BMh Sensitive 1183.0 0 0 0 0 -0.7865968023079841 Q08965 0.941340982913971 0.941340982913971 0.05421968176960945 0.05421968176960945 43.34734638046547 35.0 0.0 no 14572 chrXVI_142387r 35773 essential YPL217C 762 + CCGGAATTAATAGAGACTCA P|255|R P|255|L BMS1 BMh Sensitive 1183.0 0 0 0 0 0.01079840922615491 Q08965 0.9432820081710817 0.9430609941482544 1.0 0.15625110268592834 41.35755183401602 40.0 0.0 no 14573 chrXVI_142406r 35774 essential YPL217C 743 + ATTCACAGATTTAACTCATC F|249|L silent|TTC>TTT|F|249 T|250|R T|250|I BMS1 BMh Sensitive 1183.0 0 0 0 0 1.201518288518375 Q08965 0.9387490153312684 0.9476869702339172 0.9472420215606691 0.7773924469947815 0.4708236753940582 0.16616792976856232 38.61175492235458 30.0 0.0 no 14574 chrXVI_142436r 35775 essential YPL217C 713 + GAACGAACATCCCTATATGT N|239|K silent|AAC>AAT|N|239 BMS1 BMh Sensitive 1183.0 0 0 0 0 -0.20812466890564227 Q08965 0.9439849853515624 0.017251566052436832 43.98196565308774 40.0 0.0 no 14575 chrXVI_142426 35776 essential YPL217C 726 - AATCTGTCAGCCAACATATA R|248|T R|248|K BMS1 BMh Sensitive 1183.0 0 0 0 0 -0.10884735161972088 Q08965 0.932735025882721 0.955805003643036 0.015858422964811325 0.033986371010541916 43.329804687463884 35.0 0.0 no 14576 chrXVI_142342r 35777 essential YPL217C 807 + GCTATCTATGGTTATTTGCA A|270|G A|270|V I|271|M silent|ATC>ATT|I|271 BMS1 BMh Sensitive 1183.0 0 0 0 0 0.17384724443926414 Q08965 0.9484469890594482 0.9504740238189696 0.9598389863967896 0.04972488433122635 0.3246974050998688 0.11788181215524672 46.60461127483006 35.0 0.0 no 14577 chrXVI_142530r 35778 essential YPL217C 619 + TATCTGGTGTGATTAATGGA S|208|C S|208|F BMS1 BMh Sensitive 1183.0 0 0 0 0 0.3103371616622281 Q08965 0.945252001285553 0.9294660091400146 0.0 0.0 41.81878573697486 35.0 0.0 no 14578 chrXVI_142546r 35779 essential YPL217C 603 + GCAAAATTATTTTACCTATC A|202|G A|202|V BMS1 BMh Sensitive 1183.0 0 0 0 0 1.0638957538680829 Q08965 0.9484469890594482 0.9504740238189696 0.0 0.0 36.509045017621425 25.0 0.0 no 14579 chrXVI_142789 35782 essential YPL217C 363 - ATCGCATTCAGATCGTCCGC silent|GCG>GCC|A|127 silent|GCG>GCA|A|127 A|127|P A|127|T BMS1 BMh Sensitive 1183.0 0 0 0 0 1.3346608932147317 Q08965 0.9573720097541808 0.9523990154266356 0.019549202173948288 0.021000446751713756 54.30588770267589 55.00000000000001 0.0 no 14580 chrXVI_142790 35783 essential YPL217C 362 - TCGCATTCAGATCGTCCGCA A|127|P A|127|T silent|GCG>GCC|A|127 silent|GCG>GCA|A|127 BMS1 BMh Sensitive 1183.0 0 0 0 0 -0.9099891890756788 Q08965 0.9573720097541808 0.9523990154266356 0.019549202173948288 0.021000446751713756 55.4829696503158 55.00000000000001 0.0 no 14581 chrXVI_142840 35785 essential YPL217C 312 - TTACCAGAGACAACAGTAAT G|110|A G|110|D G|110|R G|110|S BMS1 BMh Sensitive 1183.0 0 0 0 0 -0.4237260732297691 Q08965 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.11048924922943117 0.008849486708641052 0.00597230950370431 0.30772724747657776 39.74000173643867 35.0 0.0 no 14582 chrXVI_142981 35789 essential YPL217C 171 - TCAGGGGTACGATCAACCAT E|64|Q E|64|K BMS1 BMh Sensitive 1183.0 0 0 0 0 0.11468275820087336 Q08965 0.956179976463318 0.9475290179252625 0.2280219942331314 0.31055766344070435 49.81319534546635 50.0 0.0 no 14583 chrXVI_143055 35790 essential YPL217C 97 - CATCTTACCTGGGGCTGCCA K|38|N silent|AAG>AAA|K|38 BMS1 BMh Sensitive 1183.0 0 0 0 0 -1.9164258931404548 Q08965 0.9355990290641784 0.2091161608695984 60.50568725028314 60.0 0.0 no 14584 chrXVI_153672 35796 essential YPL211W 177 + AGACCTAACTTGATGTCTCT P|61|A P|61|S P|61|R P|61|L NIP7 Nuclear ImPort 181.0 0 0 0 0 0.3895329157994695 Q08962 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.3522988855838776 0.2389441877603531 0.16544999182224274 0.0994093343615532 46.440880492246656 40.0 1.0 no 14585 chrXVI_153675r 35797 essential YPL211W 183 - ATACCCAGAGACATCAAGTT G|67|A G|67|D G|67|R G|67|S NIP7 Nuclear ImPort 181.0 0 0 0 0 -0.6372395592483016 Q08962 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.0 0.0 0.0 0.0 46.020909201500615 40.0 1.0 no 14586 chrXVI_153818 35798 essential YPL211W 323 + ATACGGTAATCATGTGTTAA Y|109|* silent|TAC>TAT|Y|109 NIP7 Nuclear ImPort 181.0 0 0 0 0 0.08416718278446339 Q08962 38.8302734314546 30.0 1.0 no 14587 chrXVI_153870r 35799 essential YPL211W 378 - ACAATAACACCGGCGTGTTC V|133|L V|133|M NIP7 Nuclear ImPort 181.0 0 0 0 0 -1.5873024711263777 Q08962 0.9539830088615416 0.9587630033493042 0.12508587539196014 0.005737936124205589 47.92838144336964 50.0 1.0 no 14588 chrXVI_154807r 35801 essential YPL210C 1383 + ATACCATTTTGGAAACACGT P|463|A P|463|S P|463|R P|463|L SRP72 Signal Recognition Particle 640.0 0 0 0 0 0.13578039655498989 P38688 1.0004199743270874 0.9926369786262512 0.9753050208091736 0.9834169745445251 0.6916714906692505 0.6630606055259705 0.4610474109649658 0.2849031686782837 41.82215657940037 35.0 0.0 no 14589 chrXVI_155036 35805 essential YPL210C 1157 - CCTTCTCTATTATTAGCAAT K|392|N silent|AAG>AAA|K|392 E|391|D silent|GAG>GAA|E|391 SRP72 Signal Recognition Particle 640.0 0 0 0 0 -0.660503701841908 P38688 0.9806249737739564 0.9933249950408936 0.42035651206970215 0.3495158851146698 43.07950767161958 30.0 0.0 no 14590 chrXVI_155036r 35806 essential YPL210C 1154 + CCAATTGCTAATAATAGAGA Q|386|E Q|386|* SRP72 Signal Recognition Particle 640.0 0 0 0 0 -0.1835828811733625 P38688 1.0026899576187134 0.23155201971530914 36.96464967534649 30.0 0.0 no 14591 chrXVI_155088 35807 essential YPL210C 1105 - TCCATCTGTTCCACTTAAAA G|375|R G|375|R G|375|A G|375|E SRP72 Signal Recognition Particle 640.0 0 0 0 0 -0.010929780631685343 P38688 0.9727219939231871 0.9727219939231871 0.9903749823570251 0.9759219884872437 0.6016576886177063 0.6016576886177063 0.6496233940124512 0.9318487644195556 44.49648094461685 35.0 0.0 no 14592 chrXVI_155098r 35808 essential YPL210C 1092 + ACTACAAAAACCATTTTAAG T|365|S T|365|I T|366|R T|366|I SRP72 Signal Recognition Particle 640.0 0 0 0 0 0.42090202931314985 P38688 0.9913139939308168 0.9893620014190674 0.8982250094413757 0.9084240198135376 0.1272517591714859 0.4144338071346283 0.4468044638633728 0.4600993990898132 32.56230398859191 25.0 0.0 no 14593 chrXVI_155618r 35815 essential YPL210C 572 + ATTCAATGAATCATTCATCA F|192|L silent|TTC>TTT|F|192 SRP72 Signal Recognition Particle 640.0 0 0 0 0 0.12496253288996335 P38688 0.9824680089950562 0.2583790719509125 37.14502048116833 25.0 0.0 no 14594 chrXVI_155608r 35816 essential YPL210C 582 + TCATTCATCATGGCATCCGT S|195|* S|195|L F|196|L silent|TTC>TTT|F|196 SRP72 Signal Recognition Particle 640.0 0 0 0 0 -2.377676671628046 P38688 0.9753659963607788 0.9824680089950562 0.0 1.0 52.37298721814597 45.0 0.0 yes 14595 chrXVI_155631 35817 essential YPL210C 562 - TTCATTGAATAATAAATCGT E|194|Q E|194|K SRP72 Signal Recognition Particle 640.0 0 0 0 0 1.2290290389213556 P38688 0.9315000176429749 0.9194509983062744 0.10083773732185364 0.08396535366773605 31.95351716488813 20.0 0.0 no 14596 chrXVI_155663r 35820 essential YPL210C 527 + ATCACCCTTAGTTACTCCTA S|177|* S|177|L P|178|A P|178|S SRP72 Signal Recognition Particle 640.0 0 0 0 0 -0.5792592838419571 P38688 0.9753659963607788 0.9314339756965636 0.9229540228843688 0.27511098980903625 0.6982982754707336 0.6587592959403992 52.03376599366528 40.0 0.0 no 14597 chrXVI_155688 35821 essential YPL210C 505 - GTTCATTAACTCTGTCGCAA M|174|I M|174|I SRP72 Signal Recognition Particle 640.0 0 0 0 0 -0.1828430030739381 P38688 0.999705970287323 0.999705970287323 0.2496294230222702 0.2496294230222702 45.73924216933256 40.0 0.0 no 14598 chrXVI_155695 35822 essential YPL210C 498 - AACTCTGTCGCAACGGATAG E|172|D silent|GAG>GAA|E|172 E|172|Q E|172|K SRP72 Signal Recognition Particle 640.0 0 0 0 0 -0.10651287147043498 P38688 0.9933249950408936 1.0004899501800537 0.9891330003738404 0.5617839694023132 0.5569643974304199 0.8474460244178772 45.666443277325975 50.0 0.0 no 14599 chrXVI_155873r 35824 essential YPL210C 317 + TCTCGATACGGTACTAAAAA silent|CTC>CTG|L|107 silent|CTC>CTT|L|107 L|107|V L|107|F SRP72 Signal Recognition Particle 640.0 0 0 0 1 -0.054535669032400036 P38688 0.9254159927368164 0.9341800212860109 0.7809782028198242 0.23458579182624814 37.428260571061685 35.0 0.0 no 14600 chrXVI_155885r 35825 essential YPL210C 305 + TATCACAGATGATCTCGATA I|103|M silent|ATC>ATT|I|103 T|104|R T|104|I SRP72 Signal Recognition Particle 640.0 0 0 0 0 0.3892999255857778 P38688 0.9338020086288452 0.8989629745483398 0.9091619849205016 0.13774973154067993 0.5061321854591371 0.19627980887889865 40.851054688602574 35.0 0.0 no 14601 chrXVI_156035 35828 essential YPL210C 158 - CCTTTTGATACTTGTCCTGT K|59|N silent|AAG>AAA|K|59 SRP72 Signal Recognition Particle 640.0 0 0 0 0 0.6276582097097629 P38688 0.912319004535675 0.4620673656463623 50.74180805119517 40.0 0.0 no 14602 chrXVI_156774r 35832 essential YPL209C 797 + CTACCTTTCTCCAGAAATGG Y|267|* silent|TAC>TAT|Y|267 L|268|V L|268|F 0 0 0 0 -0.4447408278563677 P38991 0.9950990080833436 1.0031700134277344 0.0 0.0 1.731220006942749 1.118899941444397 46.60470331115585 45.0 0.0 no 14603 chrXVI_156887r 35834 essential YPL209C 684 + AAACCTGAAAATATACTAAT P|230|A P|230|S P|230|R P|230|L 0 1 0 0 -0.9925721443301928 P38991 1.0004199743270874 0.9926369786262512 0.9753050208091736 0.9834169745445251 0.0 0.0 0.0 0.0 30.328512724106933 20.0 0.0 no 14604 chrXVI_156930 35835 essential YPL209C 644 - TCTTTTTATGCATATAATCT K|221|N silent|AAG>AAA|K|221 0 0 0 0 0.4801570789609075 P38991 0.95727801322937 0.07381206750869751 -0.3297599852085113 37.456193160753905 20.0 0.0 no 14605 chrXVI_156937 35836 essential YPL209C 637 - ATGCATATAATCTAGGGCAT M|218|I M|218|I 0 0 0 0 -0.7500664741725215 P38991 0.9756749868392944 0.9756749868392944 0.021242121234536167 0.021242121234536167 43.60255947767644 35.0 0.0 no 14606 chrXVI_157088r 35838 essential YPL209C 483 + CCGAATCTAACTAAATCATA P|162|R P|162|L L|164|V silent|CTA>TTA|L|164 0 0 0 0 0.1953713000068716 P38991 0.95032000541687 0.9589239954948424 0.9703750014305116 0.02554849535226822 0.0903448760509491 0.4704989194869995 0.5070599913597107 36.188718166122726 30.0 0.0 no 14607 chrXVI_157088 35839 essential YPL209C 486 - CCGTATGATTTAGTTAGATT G|169|R G|169|S 0 0 0 0 0.04997190916587122 P38991 0.9477360248565674 0.9668909907341005 0.009015139192342758 0.2960216999053955 41.22902726491321 30.0 0.0 no 14608 chrXVI_157228r 35842 essential YPL209C 343 + TCGGTAAAGTTTATTGCGTT F|115|L silent|TTC>TTT|F|115 0 0 0 0 0.9209982072986932 P38991 0.9022229909896852 0.59977787733078 0.5621399879455566 43.27136951152926 35.0 0.0 no 14609 chrXVI_157274r 35844 essential YPL209C 297 + TCACTCGATGACTTTGAACT L|101|V L|101|F S|100|* S|100|L 0 0 0 0 0.36175941128651945 P38991 0.9703750014305116 0.9798439741134644 0.9508730173110962 0.014006667770445349 0.06363601237535478 0.08867010474205017 0.9100800156593324 0.7404000163078308 43.189297090130594 40.0 0.0 no 14610 chrXVI_157275r 35845 essential YPL209C 296 + ATCACTCGATGACTTTGAAC S|100|* S|100|L L|101|V L|101|F 0 0 0 0 -0.3385438181631042 P38991 0.9508730173110962 0.9703750014305116 0.9798439741134644 0.08867010474205017 0.014006667770445349 0.06363601237535478 0.9100800156593324 0.7404000163078308 41.42178951509169 40.0 0.0 no 14611 chrXVI_157278 35846 essential YPL209C 296 - GTTCAAAGTCATCGAGTGAT E|105|Q E|105|K 0 0 0 0 -1.2236875943700534 P38991 0.97645902633667 0.9644089937210084 0.01680297777056694 0.01303822919726372 43.31547717596504 40.0 0.0 no 14612 chrXVI_157357r 35848 essential YPL209C 214 + CCAAAATTCCATCACCTATA silent|TCC>TCG|S|72 silent|TCC>TCT|S|72 0 0 0 0 -0.18177448320901465 P38991 43.608739095351154 35.0 0.0 no 14613 chrXVI_164331r 35855 essential YPL204W 58 - GCCGTGGTAAATGTCACCAA G|26|R G|26|S G|26|A G|26|D HRR25 HO and Radiation Repair 494.0 0 0 0 0 -0.8050504632669772 P29295 0.002050495240837336 0.05732984468340874 0.502540647983551 0.0021759308874607086 -0.8217999935150146 -0.5934000015258789 -0.604200005531311 -0.219200000166893 50.23214913673149 50.0 1.0 no 14614 chrXVI_164330 35856 essential YPL204W 54 + TCCTTTGGTGACATTTACCA silent|TCC>TCG|S|19 silent|TCC>TCT|S|19 S|19|C S|19|F HRR25 HO and Radiation Repair 494.0 0 0 0 1 -1.0620456395800648 P29295 0.0009612349094823004 0.0003866332699544728 49.860239964765526 40.0 1.0 no 14615 chrXVI_164347r 35857 essential YPL204W 74 - CACTAATTAAGTTCGTGCCG S|31|T S|31|N HRR25 HO and Radiation Repair 494.0 0 0 0 0 1.4320559796515695 P29295 1.0 0.3543824255466461 45.16999010572238 45.0 1.0 no 14616 chrXVI_164435 35862 essential YPL204W 159 + CGCGTCTACAGATACTTAAG silent|CGC>CGG|R|54 silent|CGC>CGT|R|54 silent|GTC>GTG|V|55 silent|GTC>GTT|V|55 HRR25 HO and Radiation Repair 494.0 0 0 0 0 0.28933185662366817 P29295 43.16221541481906 45.0 1.0 no 14617 chrXVI_164438 35863 essential YPL204W 162 + GTCTACAGATACTTAAGCGG silent|GTC>GTG|V|55 silent|GTC>GTT|V|55 Y|56|* silent|TAC>TAT|Y|56 HRR25 HO and Radiation Repair 494.0 0 0 0 0 -2.702849902989187 P29295 44.266687291800736 45.0 1.0 yes 14618 chrXVI_164577r 35867 essential YPL204W 304 - CAGCATGATAACCGTCTTAA M|107|I M|107|I HRR25 HO and Radiation Repair 494.0 0 0 0 0 -1.8005810475994404 P29295 0.012313153594732285 0.012313153594732285 43.77205216889388 40.0 1.0 no 14619 chrXVI_164663 35868 essential YPL204W 387 + AAACCAGACAACTTTTTAAT P|131|A P|131|S P|131|R P|131|L HRR25 HO and Radiation Repair 494.0 0 1 0 0 -0.0801505710104965 P29295 0.0 0.0 0.0 0.0 35.458593137492244 25.0 1.0 no 14620 chrXVI_164695r 35870 essential YPL204W 422 - TAACATGAACGGTGCTACCA V|147|L V|147|I HRR25 HO and Radiation Repair 494.0 0 1 0 0 -0.9828643184168788 P29295 0.29404255747795105 1.0 45.60969152930443 45.0 1.0 no 14621 chrXVI_164757 35872 essential YPL204W 481 + CACATCGTCATATTCCTTAC H|162|D H|162|Y R|163|G R|163|C HRR25 HO and Radiation Repair 494.0 0 0 0 0 0.27947436060693204 P29295 0.003860473167151213 0.00637460220605135 0.3327963352203369 0.09770730137825012 -1.5230400562286377 -0.6505799889564514 45.836402414534966 40.0 1.0 no 14622 chrXVI_164758 35873 essential YPL204W 482 + ACATCGTCATATTCCTTACA H|162|D H|162|Y R|163|G R|163|C HRR25 HO and Radiation Repair 494.0 0 0 0 0 -0.07583620647913153 P29295 0.003860473167151213 0.00637460220605135 0.3327963352203369 0.09770730137825012 -1.5230400562286377 -0.6505799889564514 45.836402414534966 35.0 1.0 no 14623 chrXVI_164879 35875 essential YPL204W 603 + GTCTTGATCTATTTTTGTAA silent|GTC>GTG|V|202 silent|GTC>GTT|V|202 HRR25 HO and Radiation Repair 494.0 0 0 0 0 0.0741654399898935 P29295 39.39958192998904 25.0 1.0 no 14624 chrXVI_164981 35877 essential YPL204W 705 + AGCGTGGAAACTCTATGTTC S|236|R silent|AGC>AGT|S|236 HRR25 HO and Radiation Repair 494.0 0 0 0 0 0.8830027263592106 P29295 0.03981423005461693 45.53272541626968 45.0 1.0 no 14625 chrXVI_165130r 35878 essential YPL204W 857 - ACATTGTCCAATCGAACAAG M|292|I M|292|I HRR25 HO and Radiation Repair 494.0 0 0 0 0 0.21791523984114924 P29295 0.6497696042060852 0.6497696042060852 0.04608000069856644 0.04608000069856644 40.911830440327655 40.0 1.0 no 14626 chrXVI_165123 35879 essential YPL204W 847 + ACAACGACCACTTGTTCGAT H|283|Q silent|CAC>CAT|H|283 N|284|K silent|AAC>AAT|N|284 HRR25 HO and Radiation Repair 494.0 0 0 0 0 0.21539256667173545 P29295 1.0 0.035347003489732735 -0.7079399824142456 0.2897999882698059 -0.9160000085830688 46.50174290572289 45.0 1.0 no 14627 chrXVI_165145 35880 essential YPL204W 869 + GACAATGTTGCGTTACACAA T|291|R T|291|I HRR25 HO and Radiation Repair 494.0 0 0 0 0 0.5035116420811316 P29295 0.006789240054786204 0.056246869266033166 42.666053207401205 40.0 1.0 no 14628 chrXVI_165319r 35884 essential YPL204W 1046 - TGTCTTCATTCTTGTAATAG D|355|H D|355|N E|354|Q E|354|K HRR25 HO and Radiation Repair 494.0 0 0 0 0 0.21276065086643847 P29295 0.1148855686187744 0.5154540538787842 0.5454456210136414 0.6863183379173279 40.02551326267025 30.0 1.0 no 14629 chrXVI_185939 35885 essential YPL190C 1767 - CCCTGGTAATAGTTTGTTTG Q|595|H silent|CAG>CAA|Q|595 G|596|R G|596|S NAB3 Nuclear polyAdenylated RNA-Binding 802.0 0 0 0 0 0.20700895133779368 P38996 0.9570760130882264 0.941340982913971 0.951104998588562 0.16493284702301025 0.1568574607372284 0.7913581132888794 47.1985222826595 40.0 0.0 no 14630 chrXVI_185939r 35886 essential YPL190C 1764 + CCTCAAACAAACTATTACCA Q|590|E Q|590|* P|589|R P|589|L NAB3 Nuclear polyAdenylated RNA-Binding 802.0 0 0 0 0 0.08449393187570739 P38996 0.9590039849281312 0.9432820081710817 0.9430609941482544 0.4560546576976776 0.7915911674499512 0.4123483598232269 40.40529018890783 35.0 0.0 no 14631 chrXVI_185940r 35887 essential YPL190C 1763 + TCCTCAAACAAACTATTACC P|589|R P|589|L P|589|A P|589|S NAB3 Nuclear polyAdenylated RNA-Binding 802.0 0 0 0 0 0.4580042623475549 P38996 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.7915911674499512 0.4123483598232269 0.5196723937988281 0.4596651792526245 39.996790959347436 35.0 0.0 no 14632 chrXVI_185969r 35889 essential YPL190C 1734 + GTTCCAAACGGCCCAGCTGT P|580|A P|580|S P|580|R P|580|L NAB3 Nuclear polyAdenylated RNA-Binding 802.0 0 0 0 0 -1.1232215181940082 P38996 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.9402732849121094 0.6127199530601501 0.7342277765274048 0.9228687286376952 58.949778973927145 60.0 0.0 no 14633 chrXVI_185978 35891 essential YPL190C 1728 - GGGCCGTTTGGAACAGGAAG G|582|A G|582|D G|582|R G|582|S NAB3 Nuclear polyAdenylated RNA-Binding 802.0 0 0 0 0 -0.4069408131462152 P38996 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.9367048740386964 0.6086582541465759 0.8061050176620483 0.8200277090072632 51.416719909060475 60.0 0.0 no 14634 chrXVI_186143r 35894 essential YPL190C 1560 + ACTTTCTACAAAGGCTCACA T|521|S T|521|I F|522|L silent|TTC>TTT|F|522 NAB3 Nuclear polyAdenylated RNA-Binding 802.0 0 0 0 0 0.26142251526019844 P38996 0.9491789937019348 0.9472420215606691 0.9387490153312684 0.0 0.0 0.0 44.96630045937047 40.0 0.0 no 14635 chrXVI_186214r 35896 essential YPL190C 1489 + TCAATGATGCCGCATATAAT I|497|M silent|ATC>ATT|I|497 NAB3 Nuclear polyAdenylated RNA-Binding 802.0 0 0 0 0 0.04413526546067986 P38996 0.9598389863967896 0.015107246115803719 42.448293522609454 35.0 0.0 no 14636 chrXVI_186215r 35897 essential YPL190C 1488 + ATCAATGATGCCGCATATAA I|497|M silent|ATC>ATT|I|497 NAB3 Nuclear polyAdenylated RNA-Binding 802.0 0 0 0 0 -0.058448956757792485 P38996 0.9598389863967896 0.015107246115803719 42.448293522609454 35.0 0.0 no 14637 chrXVI_186239 35898 essential YPL190C 1467 - AGCTTTCCCAGTTCCATTCT K|495|N silent|AAG>AAA|K|495 G|494|A G|494|E NAB3 Nuclear polyAdenylated RNA-Binding 802.0 0 0 0 0 -0.055063620447273545 P38996 0.9355990290641784 0.9499930143356324 0.9438679814338684 0.013445749878883362 0.0695754736661911 0.08757694810628891 58.03315925107883 45.0 0.0 no 14638 chrXVI_186497r 35903 essential YPL190C 1206 + GCTCGTCCTCAATTTGATCA R|404|G R|404|C A|403|G A|403|V NAB3 Nuclear polyAdenylated RNA-Binding 802.0 0 0 0 0 -0.26745233447904393 P38996 0.8994590044021606 0.8926740288734436 0.9484469890594482 0.9504740238189696 0.0 0.0 0.04805946722626686 0.018585028126835827 0.08736000210046768 0.08907999843358994 0.3616000115871429 0.3453199863433838 -0.8058199882507324 -0.435259997844696 0.11980000138282774 1.0810799598693848 50.92474755781865 45.0 0.0 no 14639 chrXVI_186585 35904 essential YPL190C 1121 - TTGCATCTCTAACGCTTTGA A|380|P A|380|T D|379|H D|379|N NAB3 Nuclear polyAdenylated RNA-Binding 802.0 0 0 0 0 -0.2720024073683959 P38996 0.9573720097541808 0.9523990154266356 0.9486550092697144 0.956179976463318 0.0 0.0 0.050305910408496864 0.11989599466323853 6.201720237731934 5.628859996795653 -0.4682599902153015 -0.3378199934959412 -0.25095999240875244 -0.40046000480651855 46.82375385288634 40.0 0.0 no 14640 chrXVI_186626r 35905 essential YPL190C 1077 + ATCAATATCAAAAATGCCTT I|360|M silent|ATC>ATT|I|360 NAB3 Nuclear polyAdenylated RNA-Binding 802.0 0 0 0 0 0.05853582358101344 P38996 0.9598389863967896 0.0 -0.08009999990463257 1.2863999605178833 36.156759641148774 25.0 0.0 no 14641 chrXVI_186679r 35906 essential YPL190C 1024 + TTTCTAAGGAGGATTTATTT S|343|C S|343|F NAB3 Nuclear polyAdenylated RNA-Binding 802.0 0 1 0 0 0.01848440811744856 P38996 0.945252001285553 0.9294660091400146 0.012067388743162157 0.0061547448858618745 1.1117000579833984 0.930999994277954 38.07568689637924 25.0 0.0 no 14642 chrXVI_186610 35908 essential YPL190C 1096 - GTCAAACTGAATGAATCCAA D|372|H D|372|N Q|370|H silent|CAG>CAA|Q|370 NAB3 Nuclear polyAdenylated RNA-Binding 802.0 0 0 0 0 -0.08054315785642803 P38996 0.9486550092697144 0.956179976463318 0.9570760130882264 0.01953711174428463 0.34236791729927063 0.0 1.135740041732788 0.3334600031375885 -0.14018000662326813 37.93479860421672 35.0 0.0 no 14643 chrXVI_186693r 35910 essential YPL190C 1010 + GCCGCTAAAGAACGTTTCTA P|338|R P|338|L P|338|A P|338|S NAB3 Nuclear polyAdenylated RNA-Binding 802.0 0 1 0 0 -1.1945664064014478 P38996 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 3.761600017547608 0.7096999883651733 3.099179983139038 4.346819877624512 46.37395365741952 45.0 0.0 no 14644 chrXVI_186722 35911 essential YPL190C 984 - CCAATGAATAATCTTGACTT G|335|R G|335|S NAB3 Nuclear polyAdenylated RNA-Binding 802.0 0 0 0 0 -1.2969327259482748 P38996 0.941340982913971 0.951104998588562 0.0 0.0 4.7011399269104 1.319700002670288 37.788556377466996 30.0 0.0 no 14645 chrXVI_186803 35913 essential YPL190C 903 - TCGTGTTCTTCTTCGGTAAT D|308|H D|308|N NAB3 Nuclear polyAdenylated RNA-Binding 802.0 0 0 0 0 0.4648196515262385 P38996 0.9486550092697144 0.956179976463318 0.035103246569633484 0.1168874204158783 48.043045496328496 40.0 0.0 no 14646 chrXVI_186857 35916 essential YPL190C 849 - CGTCTTTGGGCATCTGACAA R|289|T R|289|K NAB3 Nuclear polyAdenylated RNA-Binding 802.0 0 0 0 0 -0.5214473309698492 P38996 0.932735025882721 0.955805003643036 0.4288209080696106 1.0 50.222436461605646 50.0 0.0 no 14647 chrXVI_186908r 35918 essential YPL190C 795 + GCTAGCGCCTCAGCCACAAG A|266|G A|266|V S|267|R silent|AGC>AGT|S|267 NAB3 Nuclear polyAdenylated RNA-Binding 802.0 0 0 0 0 -2.256129040370954 P38996 0.9484469890594482 0.9504740238189696 0.9417110085487366 0.3674240112304688 0.27678656578063965 0.08717475831508636 59.35702711337609 65.0 0.0 yes 14648 chrXVI_187007 35919 essential YPL190C 699 - GCAGACATCTTTTCTTCTTG A|240|P A|240|T M|238|I M|238|I NAB3 Nuclear polyAdenylated RNA-Binding 802.0 0 0 0 0 0.8225015642204051 P38996 0.9573720097541808 0.9523990154266356 0.9553959965705872 0.9553959965705872 0.021388718858361244 0.032828297466039665 1.0 1.0 47.11938985561272 40.0 0.0 no 14649 chrXVI_187191 35920 essential YPL190C 515 - GTTCTTTTTCCAATGTTTCA E|178|Q E|178|K NAB3 Nuclear polyAdenylated RNA-Binding 802.0 0 1 0 0 0.4888682957597367 P38996 0.956179976463318 0.9475290179252625 0.34773293137550354 0.36015677452087397 45.88454234008458 30.0 0.0 no 14650 chrXVI_187258 35922 essential YPL190C 448 - CTCATCCTCACCGTCTTCAG E|156|Q E|156|K D|155|H D|155|N NAB3 Nuclear polyAdenylated RNA-Binding 802.0 0 0 0 0 0.4721236612683305 P38996 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.5764462351799011 0.8889877200126648 0.04253117740154266 0.13281016051769254 56.06832905226037 55.00000000000001 0.0 no 14651 chrXVI_187555 35924 essential YPL190C 151 - TTCATTTTCCTCCTCCCTTT E|57|Q E|57|K NAB3 Nuclear polyAdenylated RNA-Binding 802.0 0 0 0 0 -2.4629524429005665 P38996 0.956179976463318 0.9475290179252625 0.20603010058403012 0.2947487831115723 57.16090704080705 40.0 0.0 yes 14652 chrXVI_187648 35925 essential YPL190C 58 - CTCGTTAGAGTTACTATCGA E|26|Q E|26|K NAB3 Nuclear polyAdenylated RNA-Binding 802.0 0 0 0 0 1.2831146571592105 P38996 0.956179976463318 0.9475290179252625 0.5836981534957886 0.4301617443561554 44.1798236464337 40.0 0.0 no 14653 chrXVI_187689 35928 essential YPL190C 17 - TATCTTGAACATCACTGTTA D|12|H D|12|N NAB3 Nuclear polyAdenylated RNA-Binding 802.0 0 0 0 0 1.1192087923283354 P38996 0.9486550092697144 0.956179976463318 39.8502805901615 30.0 0.0 no 14654 chrXVI_229474 35929 essential YPL169C 1345 - ATTCATTGGAACAATTACCC M|454|I M|454|I MEX67 Messenger RNA EXport factor of 67 kDa 599.0 0 0 0 0 -0.09961318385623316 Q99257 0.9553959965705872 0.9553959965705872 0.1911153495311737 0.1911153495311737 1.3643800020217896 1.3643800020217896 42.346465800418635 35.0 0.0 no 14655 chrXVI_229686r 35930 essential YPL169C 1130 + ACAACCCAATGAATACTCAA Q|378|E Q|378|* P|379|A P|379|S MEX67 Messenger RNA EXport factor of 67 kDa 599.0 0 0 0 0 -0.2911116226590417 Q99257 0.9590039849281312 0.9562489986419678 0.9498909711837769 0.8214688897132874 0.1226034089922905 0.05814629048109055 0.4959399998188019 2.202699899673462 2.8591001033782963 40.14847247262247 35.0 0.0 no 14656 chrXVI_229738 35931 essential YPL169C 1081 - AGTCTTGAATATACTATTAA K|366|N silent|AAG>AAA|K|366 MEX67 Messenger RNA EXport factor of 67 kDa 599.0 0 0 0 0 0.12287091011098472 Q99257 0.9355990290641784 0.4052501618862152 0.4023599922657013 33.26047139402823 20.0 0.0 no 14657 chrXVI_229844r 35934 essential YPL169C 972 + TCGGACCAAACTCCAGCATT S|325|W S|325|L D|326|E silent|GAC>GAT|D|326 MEX67 Messenger RNA EXport factor of 67 kDa 599.0 0 0 0 0 -0.35035286379929104 Q99257 0.9288619756698608 0.9298099875450134 0.9532920122146606 0.08371353149414062 0.4193372428417206 0.5432189702987671 50.76542361421463 50.0 0.0 no 14658 chrXVI_229875r 35936 essential YPL169C 941 + TTCTACTATTCCTCCATCTA S|315|C S|315|F T|316|S T|316|I MEX67 Messenger RNA EXport factor of 67 kDa 599.0 0 0 0 0 0.6233714145253267 Q99257 0.945252001285553 0.9294660091400146 0.9491789937019348 0.9472420215606691 0.006332206539809704 0.003266760613769293 1.0 0.01372604351490736 -0.06362000107765198 -0.13289999961853027 0.02590000070631504 0.19288000464439392 48.95433246593456 35.0 0.0 no 14659 chrXVI_230041 35937 essential YPL169C 778 - CTTCATCGGTAATGAGTAAA M|265|I M|265|I silent|CCG>CCC|P|264 silent|CCG>CCA|P|264 MEX67 Messenger RNA EXport factor of 67 kDa 599.0 0 1 0 0 -1.1805033002209626 Q99257 0.9553959965705872 0.9553959965705872 0.6447885036468506 0.6447885036468506 39.0635837146001 35.0 0.0 no 14660 chrXVI_230134 35938 essential YPL169C 685 - TTCAGTGCGATACAACTTAT E|235|Q E|235|K MEX67 Messenger RNA EXport factor of 67 kDa 599.0 0 0 0 0 -0.25844327183686416 Q99257 0.956179976463318 0.9475290179252625 0.12494896352291107 0.2807748019695282 42.14854843976195 35.0 0.0 no 14661 chrXVI_230346r 35943 essential YPL169C 470 + TACAGAAAAAAGTTTGATAG T|158|R T|158|I MEX67 Messenger RNA EXport factor of 67 kDa 599.0 0 0 0 0 0.5182478763389562 Q99257 0.9476869702339172 0.9472420215606691 0.5327267050743103 0.1973044127225876 29.17301820892737 25.0 0.0 no 14662 chrXVI_230426 35948 essential YPL169C 393 - ACGCCCTTTTGAATTAGCTC G|137|A G|137|D V|138|L V|138|I MEX67 Messenger RNA EXport factor of 67 kDa 599.0 0 0 0 0 0.4565081224640116 Q99257 0.9499930143356324 0.9446240067481996 0.9539830088615416 0.9574310183525084 0.0 0.0 1.0 0.2514468729496002 50.52138181996509 45.0 0.0 no 14663 chrXVI_230513r 35949 essential YPL169C 303 + GACACCATTTCGTTCTTGAG D|102|E silent|GAC>GAT|D|102 T|103|S T|103|I MEX67 Messenger RNA EXport factor of 67 kDa 599.0 0 0 0 0 0.4983304452002064 Q99257 0.9532920122146606 0.9491789937019348 0.9472420215606691 0.5126733779907227 0.07066182047128677 0.01443622726947069 47.661431007675894 45.0 0.0 no 14664 chrXVI_230555r 35951 essential YPL169C 261 + TTCGAACTTTTAGATAACAA F|88|L silent|TTC>TTT|F|88 L|90|V L|90|F MEX67 Messenger RNA EXport factor of 67 kDa 599.0 0 0 0 0 0.4401067468153629 Q99257 0.9387490153312684 0.9512209892272948 0.9587849974632264 0.24571165442466736 0.8043767213821411 0.35155656933784485 34.14758967515473 25.0 0.0 no 14665 chrXVI_230611r 35952 essential YPL169C 205 + AAGCAGAATCGTTAATGAAA A|70|G A|70|V MEX67 Messenger RNA EXport factor of 67 kDa 599.0 0 0 0 0 0.3573784784214259 Q99257 0.9484469890594482 0.9504740238189696 0.028987353667616844 0.15310372412204742 34.662170451366194 30.0 0.0 no 14666 chrXVI_247119r 35956 essential YPL160W 132 - TCTTCAGAGTCCATTGTAAT E|51|Q E|51|K E|50|Q E|50|K CDC60 Cell Division Cycle 1090.0 0 0 0 0 1.5199152550795407 P26637 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.1158558502793312 0.10680044442415236 0.4648977220058441 0.7727897763252258 45.32355902148107 35.0 1.0 no 14667 chrXVI_247120r 35957 essential YPL160W 133 - CTCTTCAGAGTCCATTGTAA E|51|Q E|51|K E|50|Q E|50|K CDC60 Cell Division Cycle 1090.0 0 0 0 0 0.9040494465191936 P26637 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.1158558502793312 0.10680044442415236 0.4648977220058441 0.7727897763252258 47.265716844747544 40.0 1.0 no 14668 chrXVI_247157 35958 essential YPL160W 167 + TCCTAAATTCATGTCGTCTA P|57|R P|57|L P|57|A P|57|S CDC60 Cell Division Cycle 1090.0 0 1 0 0 0.5604881794703441 P26637 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.039527688175439835 0.02348656952381134 0.11386137455701828 0.07008612155914308 44.332354581100454 35.0 1.0 no 14669 chrXVI_247185r 35960 essential YPL160W 198 - TGCATAACACCGTTCATATA M|72|I M|72|I CDC60 Cell Division Cycle 1090.0 0 0 0 0 -1.6430206221914436 P26637 0.9553959965705872 0.9553959965705872 0.07304129004478455 0.07304129004478455 43.420805838891056 35.0 1.0 no 14670 chrXVI_247230 35961 essential YPL160W 240 + TCCAAAGTCGAATTTTCTAT silent|TCC>TCG|S|81 silent|TCC>TCT|S|81 S|81|C S|81|F CDC60 Cell Division Cycle 1090.0 0 0 1 Series([], Name: modification, dtype: object) 0 1.2066837792277958 P26637 0.945252001285553 0.9294660091400146 0.0 0.0 40.050559757310346 30.0 1.0 no 14671 chrXVI_247231r 35962 essential YPL160W 244 - ACCAATAGAAAATTCGACTT G|88|R G|88|S G|88|A G|88|D CDC60 Cell Division Cycle 1090.0 0 0 0 0 -1.1993661874090042 P26637 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.12499788403511047 0.027163993567228317 0.04124542325735092 0.019549071788787842 36.68212216061261 30.0 1.0 no 14672 chrXVI_247463 35967 essential YPL160W 473 + ATCTAAAGCCGCAGCCAAGA S|159|C S|159|F CDC60 Cell Division Cycle 1090.0 0 0 0 0 0.1858457174964056 P26637 0.945252001285553 0.9294660091400146 0.03247207403182984 0.013016482815146444 50.27605932960353 50.0 1.0 no 14673 chrXVI_247477r 35971 essential YPL160W 490 - GTACTTACCACGGCCCTTCT K|169|N silent|AAG>AAA|K|169 CDC60 Cell Division Cycle 1090.0 0 0 0 0 -0.6538551746811311 P26637 0.9355990290641784 0.060854192823171616 58.65307685132586 55.00000000000001 1.0 no 14674 chrXVI_247487r 35973 essential YPL160W 500 - TTTCGAATTGGTACTTACCA E|173|Q E|173|K CDC60 Cell Division Cycle 1090.0 0 0 0 0 -1.2437206903633715 P26637 0.956179976463318 0.9475290179252625 1.0 0.03787723183631897 43.874119492065184 35.0 1.0 no 14675 chrXVI_247583r 35975 essential YPL160W 596 - AATCACTTTCACACAAAGGT D|205|H D|205|N S|204|T S|204|N CDC60 Cell Division Cycle 1090.0 0 0 0 0 0.2354427839701721 P26637 0.9486550092697144 0.956179976463318 0.9512869715690612 0.9536849856376648 0.0 0.0 0.4608904123306274 0.2625341713428497 40.64029829618283 35.0 1.0 no 14676 chrXVI_247587r 35976 essential YPL160W 600 - GTACAATCACTTTCACACAA C|206|S C|206|Y CDC60 Cell Division Cycle 1090.0 0 0 0 0 0.4405377522879743 P26637 0.9421560168266296 0.9290120005607604 0.004218885209411383 0.004602063912898302 40.86150354402457 35.0 1.0 no 14677 chrXVI_247678r 35978 essential YPL160W 691 - GTTCATTTGCCATCTAATAA M|236|I M|236|I CDC60 Cell Division Cycle 1090.0 0 0 0 0 -1.2430204396866424 P26637 0.9553959965705872 0.9553959965705872 0.3589906990528107 0.3589906990528107 42.28729850663547 30.0 1.0 no 14678 chrXVI_247743 35979 essential YPL160W 753 + ACTATTTACTCTGAAAAAGA T|252|S T|252|I CDC60 Cell Division Cycle 1090.0 0 0 0 0 -0.21334314346509328 P26637 0.9491789937019348 0.9472420215606691 0.06858517229557037 0.0021154358983039856 33.056804631446816 25.0 1.0 no 14679 chrXVI_248057r 35982 essential YPL160W 1070 - CTCTCTTTGGTGTTAGCTTT R|363|T R|363|K K|362|N silent|AAG>AAA|K|362 CDC60 Cell Division Cycle 1090.0 0 1 0 0 -0.5505072862042145 P26637 0.932735025882721 0.955805003643036 0.9355990290641784 0.6730213165283203 0.9853445887565612 0.2593611776828766 51.09914043157261 40.0 1.0 no 14680 chrXVI_248088 35983 essential YPL160W 1098 + AAGCCGATAGTTACTGTCCC P|368|A P|368|S P|368|R P|368|L CDC60 Cell Division Cycle 1090.0 0 1 0 0 -0.16891749293819142 P26637 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.884486198425293 0.8183528184890747 0.6124838590621948 0.5512847900390625 52.696247269280995 50.0 1.0 no 14681 chrXVI_248091r 35984 essential YPL160W 1104 - TTACCTGGGACAGTAACTAT G|374|A G|374|D G|374|R G|374|S CDC60 Cell Division Cycle 1090.0 0 0 0 0 -1.0044968056874717 P26637 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.0 0.0 0.0 0.0 45.02004737983651 40.0 1.0 no 14682 chrXVI_248141r 35988 essential YPL160W 1154 - GTTCTGGATATACAGATTGT E|391|Q E|391|K CDC60 Cell Division Cycle 1090.0 0 0 0 0 -0.6724343887315952 P26637 0.956179976463318 0.9475290179252625 0.5629032850265503 0.9065432548522948 43.00171369617277 35.0 1.0 no 14683 chrXVI_248268 35990 essential YPL160W 1278 + TTGCACAAACCTGAATACTA H|428|D H|428|Y H|428|Q silent|CAC>CAT|H|428 CDC60 Cell Division Cycle 1090.0 0 0 0 0 0.25012087889096657 P26637 0.9473130106925964 0.9489949941635132 0.9588389992713928 0.002441492630168796 0.004388605710119009 0.07066308706998825 40.4845459150053 35.0 1.0 no 14684 chrXVI_248325r 35992 essential YPL160W 1338 - TACTTTTCGGTATGCATAAT K|452|N silent|AAG>AAA|K|452 CDC60 Cell Division Cycle 1090.0 0 0 0 0 0.21408074315453307 P26637 0.9355990290641784 0.5787842273712158 41.23231428458894 30.0 1.0 no 14685 chrXVI_248397r 35994 essential YPL160W 1410 - GCTAACAAGTTCTTATCCTT A|477|P A|477|T L|475|F silent|TTG>TTA|L|475 CDC60 Cell Division Cycle 1090.0 0 1 0 0 0.372148654722258 P26637 0.9573720097541808 0.9523990154266356 0.9587849974632264 0.10323170572519302 0.12437999993562697 0.01561746932566166 45.12917873456415 35.0 1.0 no 14686 chrXVI_248506r 35996 essential YPL160W 1519 - ATCAGCCTTAACCTTGTTTT D|513|H D|513|N A|512|P A|512|T CDC60 Cell Division Cycle 1090.0 0 0 0 0 0.11413854514904255 P26637 0.9486550092697144 0.956179976463318 0.9573720097541808 0.9523990154266356 0.16640767455101013 0.4708352982997894 0.1383250653743744 0.4329196810722351 48.79339158795682 35.0 1.0 no 14687 chrXVI_248478r 35997 essential YPL160W 1491 - TCGACCTTCTCACCTTTATA E|504|Q E|504|K V|503|L V|503|I CDC60 Cell Division Cycle 1090.0 0 1 0 0 0.14879806023111464 P26637 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 1.0 0.118790902197361 0.017176462337374687 0.02517605572938919 49.5973586148375 40.0 1.0 no 14688 chrXVI_248555 35998 essential YPL160W 1565 + CTACAACGAACCAGAATCTC Y|523|* silent|TAC>TAT|Y|523 N|524|K silent|AAC>AAT|N|524 CDC60 Cell Division Cycle 1090.0 0 0 0 0 -0.3503963228533721 P26637 0.9439849853515624 0.38065245747566223 41.522643690669724 45.0 1.0 no 14689 chrXVI_248571 35999 essential YPL160W 1581 + TCTCAGGTCATGTCACGTTC Q|529|E Q|529|* S|528|C S|528|F CDC60 Cell Division Cycle 1090.0 0 0 0 0 -0.7902507405727249 P26637 0.9590039849281312 0.945252001285553 0.9294660091400146 0.8643731474876404 0.02930304780602455 0.0373065210878849 52.67709689988351 50.0 1.0 no 14690 chrXVI_248862 36002 essential YPL160W 1872 + TTACTATTTAAGGATTATTA L|626|V silent|CTA>TTA|L|626 CDC60 Cell Division Cycle 1090.0 0 0 0 0 -1.276244300929207 P26637 0.9512209892272948 0.0 32.089516542977826 15.0 1.0 no 14691 chrXVI_248951r 36003 essential YPL160W 1964 - TCTTGACATCATCCTGATGT K|661|N silent|AAG>AAA|K|661 V|660|L V|660|I CDC60 Cell Division Cycle 1090.0 0 0 0 0 0.3495221555933077 P26637 0.9355990290641784 0.9539830088615416 0.9574310183525084 0.4308567941188812 0.7274803519248962 0.4905409216880798 48.041696342657254 40.0 1.0 no 14692 chrXVI_248991r 36004 essential YPL160W 2004 - CTTCTCAACTTTTGTAAAGC R|674|T R|674|K L|673|F silent|TTG>TTA|L|673 CDC60 Cell Division Cycle 1090.0 0 1 0 0 0.975487273220882 P26637 0.932735025882721 0.955805003643036 0.9587849974632264 0.012859006412327291 0.4732760488986969 0.028436232358217236 40.525871043433426 35.0 1.0 no 14693 chrXVI_249033 36006 essential YPL160W 2043 + CCATTAGACGTCTCAATTTC P|682|R P|682|L CDC60 Cell Division Cycle 1090.0 0 0 0 0 0.2670977582161338 P26637 0.9432820081710817 0.9430609941482544 0.0 0.0 44.637063205074575 40.0 1.0 no 14694 chrXVI_249114 36009 essential YPL160W 2124 + CCAAAGAAATTCTGGCCTAA P|709|R P|709|L CDC60 Cell Division Cycle 1090.0 0 0 0 0 -0.3920306125406896 P26637 0.9432820081710817 0.9430609941482544 0.00670915562659502 0.006994776427745819 42.517643280556115 40.0 1.0 no 14695 chrXVI_249129 36010 essential YPL160W 2139 + CCTAAAGGTATCAGAGCTAA P|714|R P|714|L CDC60 Cell Division Cycle 1090.0 0 0 0 0 0.8909799024881474 P26637 0.9432820081710817 0.9430609941482544 0.0 0.0 42.77857971952602 40.0 1.0 no 14696 chrXVI_249259r 36015 essential YPL160W 2272 - TTCAACAGTATCTCCCGCAT E|764|Q E|764|K V|763|L V|763|I CDC60 Cell Division Cycle 1090.0 0 0 0 0 -0.7213896999359659 P26637 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.023763353005051613 0.023205172270536426 0.2765528559684753 1.0 51.54484710225171 45.0 1.0 no 14697 chrXVI_249320 36016 essential YPL160W 2330 + TCTGAGATTATTCAATTTGA L|778|V silent|CTG>TTG|L|778 CDC60 Cell Division Cycle 1090.0 0 0 0 0 0.4439138710495419 P26637 0.9512209892272948 0.00814263429492712 36.819069968383424 25.0 1.0 no 14698 chrXVI_262398 36017 essential YPL153C 1775 - TCACACCTTGCTGAATCTCC V|598|L V|598|M silent|GTG>GTC|V|598 silent|GTG>GTA|V|598 RAD53 RADiation sensitive 821.0 0 0 0 0 0.25797314239301994 P22216 0.382086843252182 0.11494646221399307 0.10620000213384627 -0.7681999802589417 52.40562682906807 50.0 0.0 no 14699 chrXVI_262416r 36018 essential YPL153C 1754 + CAGCATTATTCAAGAAAGCC S|586|R silent|AGC>AGT|S|586 RAD53 RADiation sensitive 821.0 0 0 0 0 -0.20382856265817395 P22216 0.08039958775043488 14.774399757385256 42.191347259687525 40.0 0.0 no 14700 chrXVI_262476r 36020 essential YPL153C 1694 + TGTCAAGAGCTCAAAGAAAA silent|GTC>GTG|V|566 silent|GTC>GTT|V|566 RAD53 RADiation sensitive 821.0 0 0 0 0 -0.3811916320166671 P22216 35.93162618064389 35.0 0.0 no 14701 chrXVI_262666r 36026 essential YPL153C 1504 + ACGAATTTGTCAAAGCGCAA Y|502|* silent|TAC>TAT|Y|502 RAD53 RADiation sensitive 821.0 0 0 0 0 1.098981435981349 P22216 41.649393679127456 40.0 0.0 no 14702 chrXVI_262820 36027 essential YPL153C 1353 - GCAGCTGTCGACCTATTATT A|458|P A|458|T A|457|P A|457|T RAD53 RADiation sensitive 821.0 0 0 0 0 -0.05332012236801181 P22216 0.24858254194259646 0.5188338756561279 0.01744157075881958 0.025393540039658543 -0.7953199744224548 0.2912000119686127 -0.5280200242996216 0.14988000690937042 51.24643878795598 45.0 0.0 no 14703 chrXVI_262872 36029 essential YPL153C 1301 - CTCTTGCTTCTTCAGATATC R|440|T R|440|K A|439|P A|439|T RAD53 RADiation sensitive 821.0 0 0 0 0 0.26003262170948355 P22216 0.0763382688164711 0.5158928036689758 0.07894499599933624 0.0560164637863636 2.4385199546813965 1.0159399509429932 1.6886199712753296 2.485480070114136 47.13376910001227 40.0 0.0 no 14704 chrXVI_262983r 36033 essential YPL153C 1187 + TCTTGTGTATGTTATCCTAA L|397|V L|397|F RAD53 RADiation sensitive 821.0 0 0 0 0 0.6823766459451712 P22216 0.0 0.0 2.253900051116944 -1.3290599584579468 43.503163125219096 30.0 0.0 no 14705 chrXVI_263017r 36034 essential YPL153C 1153 + ACTCTTCGTTAGTGGATATG S|386|C S|386|F Y|385|* silent|TAC>TAT|Y|385 RAD53 RADiation sensitive 821.0 0 0 0 0 -0.4103036670243213 P22216 0.0 0.0 0.8273800015449524 -0.49167999625206 44.625174716801894 40.0 0.0 no 14706 chrXVI_263081 36036 essential YPL153C 1092 - TCTTTACCTCTGATGACTTC D|371|H D|371|N G|369|A G|369|D RAD53 RADiation sensitive 821.0 0 1 0 0 -0.3337911984667918 P22216 0.16675850749015808 0.5366080403327942 0.24031513929367065 0.07519920915365219 46.95491533799185 40.0 0.0 no 14707 chrXVI_263177 36037 essential YPL153C 996 - TCGGTTATCTTTACCAATAC D|339|H D|339|N RAD53 RADiation sensitive 821.0 0 0 0 0 0.03843852470879558 P22216 0.0 0.0 42.84018651115929 35.0 0.0 no 14708 chrXVI_263411 36041 essential YPL153C 762 - CCTTTCAATCGTACTATCCT G|261|R G|261|R L|259|F silent|TTG>TTA|L|259 RAD53 RADiation sensitive 821.0 0 0 0 0 0.3205925471865278 P22216 0.07782591134309769 0.07782591134309769 0.0 0.44132000207901 0.44132000207901 1.6318600177764893 48.63309933128056 40.0 0.0 no 14709 chrXVI_263428r 36043 essential YPL153C 742 + TGCAAAAGCTCAATCATCCA Q|249|E Q|249|* RAD53 RADiation sensitive 821.0 0 0 0 0 1.220183231442291 P22216 0.2799626290798187 0.30790001153945923 44.368879042728956 40.0 0.0 no 14710 chrXVI_263158 36046 essential YPL153C 1015 - TACTTTTGCCAGACCAAAGT V|345|L V|345|I RAD53 RADiation sensitive 821.0 0 0 0 0 0.763174979858307 P22216 0.4206172525882721 0.780070960521698 -0.3287000060081482 -0.20598000288009646 46.8547493579569 40.0 0.0 no 14711 chrXVI_263530r 36047 essential YPL153C 640 + AAGCCATTGAAAGAACTACT A|215|G A|215|V silent|GCC>GCG|A|215 silent|GCC>GCT|A|215 RAD53 RADiation sensitive 821.0 0 0 0 0 -0.003518362753083925 P22216 0.12743084132671356 0.013037086464464664 2.5994999408721924 -0.93231999874115 39.20084297162475 35.0 0.0 no 14712 chrXVI_263556 36048 essential YPL153C 617 - TTACTGTGGCAAATGCACCC V|212|L V|212|I RAD53 RADiation sensitive 821.0 0 0 0 0 0.18134859222501348 P22216 0.0 0.0 -0.6239399909973145 -0.4237000048160553 50.76467843450672 50.0 0.0 no 14713 chrXVI_263527 36049 essential YPL153C 646 - TTTCCCAGTAGTTCTTTCAA silent|GGG>GGC|G|221 silent|GGG>GGA|G|221 G|221|A G|221|E RAD53 RADiation sensitive 821.0 0 0 0 0 0.2783207630988549 P22216 0.0 0.0 3.575599908828736 3.7378199100494394 48.969274793784344 35.0 0.0 no 14714 chrXVI_263607r 36051 essential YPL153C 563 + CAACAAGACTGGTATTTTTA N|189|K silent|AAC>AAT|N|189 RAD53 RADiation sensitive 821.0 0 1 0 0 -0.2349822527011093 P22216 0.9225133061408995 37.782901510456036 30.0 0.0 no 14715 chrXVI_263663r 36055 essential YPL153C 507 + ACCTCTAAAATAGCTTCTCC silent|ACC>ACG|T|170 silent|ACC>ACT|T|170 T|170|S T|170|I RAD53 RADiation sensitive 821.0 0 0 1 Series([], Name: modification, dtype: object) 0 0.6752757998290546 P22216 0.4292699992656708 0.5288699865341187 45.8608097655702 40.0 0.0 no 14716 chrXVI_263709 36057 essential YPL153C 464 - GATCAACTTTGTTCTGCTCG D|161|H D|161|N V|160|L V|160|I RAD53 RADiation sensitive 821.0 0 1 0 0 0.7477530184373182 P22216 0.37700000405311584 0.13699999451637268 -0.03280000016093254 0.01360000018030405 -0.1881999969482422 -0.1923999935388565 47.303371932848336 45.0 0.0 no 14717 chrXVI_263813r 36058 essential YPL153C 357 + AGCAATCAGTTACTGTCTCA S|120|R silent|AGC>AGT|S|120 Q|122|E Q|122|* RAD53 RADiation sensitive 821.0 0 0 0 0 -0.2573720406920181 P22216 0.5516818761825562 0.2061370760202408 -0.3905999958515167 0.5985999703407288 47.42812360654528 40.0 0.0 no 14718 chrXVI_263845 36059 essential YPL153C 328 - GACTTTTTGCCCATTTAACC V|116|L V|116|I RAD53 RADiation sensitive 821.0 0 0 0 0 0.6194540907782657 P22216 1.0 0.25845226645469666 0.08799999952316284 -0.02219999954104424 1.8603999614715576 0.8682000041007996 48.9192512710535 40.0 0.0 no 14719 chrXVI_263904 36061 essential YPL153C 269 - CGTCTTCTCCTAGTAGTATT D|96|H D|96|N E|95|Q E|95|K RAD53 RADiation sensitive 821.0 0 0 0 0 0.001472249563941208 P22216 0.01975248008966446 0.3602980673313141 0.4385245740413666 0.74913489818573 -0.19820000231266025 -0.7332000136375427 -0.12099999934434892 0.5342000126838684 49.70513002571397 40.0 0.0 no 14720 chrXVI_263912r 36062 essential YPL153C 258 + AAGCATTTCCAAATACTACT H|88|D H|88|Y RAD53 RADiation sensitive 821.0 0 0 0 0 0.8981797470735554 P22216 0.0 0.0 0.9276000261306764 2.757999897003174 -1.857800006866455 0.7648000121116638 40.02182470541254 30.0 0.0 no 14721 chrXVI_264040 36064 essential YPL153C 133 - ATCAGCTGACAAATCTCGGA D|51|H D|51|N A|50|P A|50|T RAD53 RADiation sensitive 821.0 0 1 0 0 0.11072417768623148 P22216 0.4564497470855713 0.6710371375083923 0.20907412469387052 0.4123364388942719 1.682600021362305 0.8866000175476074 14.528800010681152 2.780600070953369 8.781599998474121 3.776000022888184 45.555627299959724 45.0 0.0 no 14722 chrXVI_264088r 36067 essential YPL153C 82 + TCGGCGAAAACATTGTGTGC I|28|M silent|ATC>ATT|I|28 silent|GGC>GGG|G|29 silent|GGC>GGT|G|29 RAD53 RADiation sensitive 821.0 0 1 0 0 0.2515118556023049 P22216 0.13512644171714785 -0.0689999982714653 -0.05220000073313713 45.935133780710316 50.0 0.0 no 14723 chrXVI_264142r 36069 essential YPL153C 28 + AATCCACGCAGGCTACTCAA S|11|C S|11|F silent|TCC>TCG|S|11 silent|TCC>TCT|S|11 RAD53 RADiation sensitive 821.0 0 0 0 0 -0.4321905984202079 P22216 0.12297820299863815 0.2257654666900635 -0.08980000019073486 -0.473800003528595 0.1738000065088272 -0.8047999739646912 50.54019190427351 50.0 0.0 no 14724 chrXVI_266534r 36074 essential YPL151C 979 + GTACTGATGACATCAGATCA T|328|S T|328|I PRP46 Pre-mRNA Processing 451.0 0 0 0 0 -1.8745290896014863 Q12417 0.9491789937019348 0.9472420215606691 0.7141581177711487 0.1045246347784996 43.43503725461186 40.0 0.0 no 14725 chrXVI_266745r 36082 essential YPL151C 768 + ATACCTGTTATTACACTAGT P|258|A P|258|S P|258|R P|258|L PRP46 Pre-mRNA Processing 451.0 0 0 0 0 -0.8110481816686221 Q12417 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.7376220226287842 0.7176554203033447 0.4987649619579315 0.3563717305660248 42.69038971908367 30.0 0.0 no 14726 chrXVI_266984 36086 essential YPL151C 532 - TGTCATTACATGCCCTGCTA M|183|I M|183|I PRP46 Pre-mRNA Processing 451.0 0 0 0 0 0.13765552757298838 Q12417 0.9553959965705872 0.9553959965705872 0.16110725700855255 0.16110725700855255 53.640477696809796 45.0 0.0 no 14727 chrXVI_267074r 36088 essential YPL151C 439 + TCGATCCTGTTGACAACGAA I|147|M silent|ATC>ATT|I|147 P|149|A P|149|S PRP46 Pre-mRNA Processing 451.0 0 0 0 0 -0.2154947619419143 Q12417 0.9598389863967896 0.9562489986419678 0.9498909711837769 0.02280397899448872 0.0 0.0 44.850919896464575 45.0 0.0 no 14728 chrXVI_267103 36089 essential YPL151C 413 - CGCATCGTACCCATCCAAGA C|144|S C|144|Y R|143|P R|143|Q PRP46 Pre-mRNA Processing 451.0 0 0 0 0 -1.6855201852000257 Q12417 0.9421560168266296 0.9290120005607604 0.9099509716033936 0.949662983417511 0.9880889654159546 0.008697125129401684 0.042443908751010895 0.10036788135766984 53.9169628711287 55.00000000000001 0.0 no 14729 chrXVI_267112r 36090 essential YPL151C 401 + TATCAATGGCCATCTTGGAT I|135|M silent|ATC>ATT|I|135 PRP46 Pre-mRNA Processing 451.0 0 0 0 0 0.11119090952180316 Q12417 0.9598389863967896 0.01203433983027935 47.25803417177332 40.0 0.0 no 14730 chrXVI_267126r 36091 essential YPL151C 387 + AAACTTTCACGCGTTATCAA L|131|V L|131|F PRP46 Pre-mRNA Processing 451.0 0 0 0 0 0.022428996692213567 Q12417 0.9512209892272948 0.9587849974632264 0.06968650966882706 0.05550605058670044 41.15359597078651 35.0 0.0 no 14731 chrXVI_267161r 36092 essential YPL151C 352 + TTCTGTCACAAAGGCCGGAA L|119|V silent|CTG>TTG|L|119 S|120|* S|120|L PRP46 Pre-mRNA Processing 451.0 0 0 0 0 -0.014610635732833275 Q12417 0.9512209892272948 0.9298099875450134 1.0 0.5174903273582458 48.79398101338053 50.0 0.0 no 14732 chrXVI_267170r 36093 essential YPL151C 343 + ACGAAAAACTTCTGTCACAA Y|115|* silent|TAC>TAT|Y|115 PRP46 Pre-mRNA Processing 451.0 0 0 0 0 0.8616338353157598 Q12417 37.27107827901682 35.0 0.0 no 14733 chrXVI_267208 36094 essential YPL151C 308 - GTTCTTCAGCAACCTCTGGT E|109|Q E|109|K E|108|Q E|108|K PRP46 Pre-mRNA Processing 451.0 0 0 0 0 0.5909611547139472 Q12417 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.6165779232978821 0.8909685015678406 0.8670254945755005 0.7408141493797302 55.46045340864151 50.0 0.0 no 14734 chrXVI_267409 36096 essential YPL151C 107 - CTTCCATTTCGCTTTGTAGG E|42|Q E|42|K M|41|I M|41|I PRP46 Pre-mRNA Processing 451.0 0 0 0 0 0.0978506402949991 Q12417 0.956179976463318 0.9475290179252625 0.9553959965705872 0.9553959965705872 0.2980073988437653 0.4264765679836273 1.0 1.0 50.73115927226343 45.0 0.0 no 14735 chrXVI_267501r 36097 essential YPL151C 12 + GATCACAAAGTCGAAAATTT H|6|D H|6|Y H|6|Q silent|CAC>CAT|H|6 PRP46 Pre-mRNA Processing 451.0 0 1 0 0 -0.3151180463497503 Q12417 0.9473130106925964 0.9489949941635132 0.9588389992713928 34.512531962426124 30.0 0.0 no 14736 chrXVI_276551r 36098 essential YPL146C 956 + AACAAAATATCAAAGAAACA T|320|R T|320|I NOP53 NucleOlar Protein 455.0 0 0 0 0 0.7655432189382424 Q12080 0.035794030874967575 0.12462425976991652 26.99579460608385 20.0 0.0 no 14737 chrXVI_276707r 36099 essential YPL146C 800 + AACTTTAGATGACAATGAAG T|268|S T|268|I NOP53 NucleOlar Protein 455.0 0 0 0 0 0.0016197619038173794 Q12080 0.33040308952331543 0.04064494371414185 33.10198165775142 30.0 0.0 no 14738 chrXVI_276747 36100 essential YPL146C 763 - TCTTTCTTTGTACTTTTCCA R|261|T R|261|K E|260|Q E|260|K NOP53 NucleOlar Protein 455.0 0 0 0 0 -1.005847067172334 Q12080 0.04758432134985924 0.6644651889801025 0.5480207800865173 0.8293449282646179 47.23930229656435 30.0 0.0 no 14739 chrXVI_276828r 36101 essential YPL146C 679 + ACAATCCCAACAATAAAGCT Y|227|* silent|TAC>TAT|Y|227 P|229|A P|229|S NOP53 NucleOlar Protein 455.0 0 1 0 0 -0.8976538906410401 Q12080 0.21539299190044406 0.048149917274713516 40.640578809135256 35.0 0.0 no 14740 chrXVI_276831 36103 essential YPL146C 679 - AGCTTTATTGTTGGGATTGT A|233|P A|233|T NOP53 NucleOlar Protein 455.0 0 0 0 0 -0.035646735227957804 Q12080 0.03928760439157486 0.11959494650363922 46.67807496956403 35.0 0.0 no 14741 chrXVI_276859r 36104 essential YPL146C 648 + TTCACAGAAATTCCACATGC F|217|L silent|TTC>TTT|F|217 T|218|R T|218|I NOP53 NucleOlar Protein 455.0 0 0 0 0 -0.7391264230719816 Q12080 0.4056468904018402 0.1800549328327179 0.0771811380982399 43.60559285098407 40.0 0.0 no 14742 chrXVI_276994 36106 essential YPL146C 516 - ACATCAAGTTTGATACCGGA V|179|L V|179|M D|178|H D|178|N NOP53 NucleOlar Protein 455.0 0 0 0 0 -0.0003830796923870797 Q12080 0.2816539704799652 0.09598062932491302 44.63585382759209 40.0 0.0 no 14743 chrXVI_277198r 36111 essential YPL146C 309 + AATCACCATAAGAATAGTAG H|105|D H|105|Y H|105|Q silent|CAC>CAT|H|105 NOP53 NucleOlar Protein 455.0 0 0 0 0 -1.1773328168342214 Q12080 0.8445854187011719 0.9945459365844728 0.7428805828094482 35.19320454917693 30.0 0.0 no 14744 chrXVI_277331r 36112 essential YPL146C 176 + TCTTTTTCATGTTGATGTTG L|60|V L|60|F NOP53 NucleOlar Protein 455.0 0 0 0 0 0.03636998415985904 Q12080 0.09618577361106873 0.04587576165795326 41.921188393602854 30.0 0.0 no 14745 chrXVI_277362 36113 essential YPL146C 148 - TTGCAAAGAGGTTATATCAC L|55|F silent|TTG>TTA|L|55 NOP53 NucleOlar Protein 455.0 0 0 0 0 -0.8744709323117841 Q12080 0.040112145245075226 39.50809588663151 35.0 0.0 no 14746 chrXVI_282690r 36114 essential YPL143W 46 - GACTCTCTTGGATCTTTGGT V|22|L V|22|I R|21|T R|21|K RPL33A Ribosomal Protein of the Large subunit 107.0 0 0 0 0 -0.8027234552796996 P05744 0.1388723999261856 0.11238576471805573 0.07577923685312271 0.08287034183740616 -0.2202399969100952 -0.1852400004863739 -0.0614200010895729 -0.1031000018119812 50.97276110185351 45.0 1.0 no 14747 chrXVI_282760 36116 essential YPL143W 113 + ACAAGATGCTCAATTTTACT Q|39|E Q|39|* RPL33A Ribosomal Protein of the Large subunit 107.0 0 1 0 0 -0.3604645511378446 P05744 1.0 0.08826000243425369 39.540675003780734 30.0 1.0 no 14748 chrXVI_282796 36117 essential YPL143W 149 + CTACGTCTACAGAGCCTCCA Y|51|* silent|TAC>TAT|Y|51 silent|GTC>GTG|V|52 silent|GTC>GTT|V|52 RPL33A Ribosomal Protein of the Large subunit 107.0 0 1 0 0 -0.08957633746778178 P05744 55.516928649122804 55.00000000000001 1.0 no 14749 chrXVI_303168r 36119 essential YPL131W 50 - TTCTTCTTCTGAAAGGAGTT R|23|T R|23|K R|22|T R|22|K RPL5 Ribosomal Protein of the Large subunit 297.0 0 1 0 0 -3.1194436677956467 P26321 0.0 0.0 0.0025521637871861453 0.013907739892601969 1.4836000204086304 -0.12219999730587006 0.313400000333786 -0.6295999884605408 1.3248000144958496 -0.225600004196167 0.40950000286102295 -0.18080000579357147 42.99884120318223 35.0 1.0 yes 14750 chrXVI_303252 36121 essential YPL131W 131 + CAACACTCCAAAGTACAGAT N|45|K silent|AAC>AAT|N|45 T|46|S T|46|I RPL5 Ribosomal Protein of the Large subunit 297.0 0 1 0 0 0.1738783044333664 P26321 0.021713823080062863 0.5762906074523926 0.008486623875796795 -0.3858000040054321 -0.6705999970436096 -0.6492000222206116 -0.3370000123977661 41.387337211760666 40.0 1.0 no 14751 chrXVI_303310 36122 essential YPL131W 189 + ATCATCTCTTCTACCATCAC I|64|M silent|ATC>ATT|I|64 I|65|M silent|ATC>ATT|I|65 RPL5 Ribosomal Protein of the Large subunit 297.0 0 0 0 0 -0.2878558432657322 P26321 0.002362480387091637 0.06435850262641908 0.09860000014305116 -1.138399958610535 48.20790883567992 40.0 1.0 no 14752 chrXVI_303370 36124 essential YPL131W 249 + CCAAGATACGGTATTACCCA P|84|R P|84|L RPL5 Ribosomal Protein of the Large subunit 297.0 0 0 0 0 0.6693786772559986 P26321 0.20226134359836576 0.0533716045320034 1.7613999843597412 1.9742000102996824 48.40398041913079 45.0 1.0 no 14753 chrXVI_303383 36126 essential YPL131W 262 + TTACCCACGGTTTGACCAAC T|89|S T|89|I silent|ACC>ACG|T|89 silent|ACC>ACT|T|89 RPL5 Ribosomal Protein of the Large subunit 297.0 0 0 0 0 -0.10562308708695424 P26321 0.11345973610877992 0.019033467397093773 -0.5260000228881836 -0.722000002861023 50.66194135241814 50.0 1.0 no 14754 chrXVI_303544 36130 essential YPL131W 423 + TTCAAGGTCTTCTTGGATAT F|142|L silent|TTC>TTT|F|142 RPL5 Ribosomal Protein of the Large subunit 297.0 0 0 0 0 0.7603275530788983 P26321 0.03590049594640732 2.285599946975708 44.40031035749332 35.0 1.0 no 14755 chrXVI_303723 36135 essential YPL131W 602 + TGGCCACGTTTCCCAATACA silent|GGC>GGG|G|202 silent|GGC>GGT|G|202 H|203|D H|203|Y RPL5 Ribosomal Protein of the Large subunit 297.0 0 0 0 0 -0.08839292068389981 P26321 0.019794393330812454 0.008229253813624382 -0.2093999981880188 0.00419999985024333 54.01779642027941 50.0 1.0 no 14756 chrXVI_303734r 36137 essential YPL131W 616 - AGCTAATTCTTCCATGTATT A|212|P A|212|T RPL5 Ribosomal Protein of the Large subunit 297.0 0 0 0 0 0.3405161222763159 P26321 0.2230248749256134 0.4889472126960754 5.77400016784668 0.10339999943971634 44.35258485301893 30.0 1.0 no 14757 chrXVI_303735r 36138 essential YPL131W 617 - CAGCTAATTCTTCCATGTAT A|212|P A|212|T RPL5 Ribosomal Protein of the Large subunit 297.0 0 0 0 0 0.2531964195386925 P26321 0.2230248749256134 0.4889472126960754 5.77400016784668 0.10339999943971634 45.431080761504525 35.0 1.0 no 14758 chrXVI_305440r 36139 high_effect YPL129W 40 - TTCTGGCAGAATGTGTTGTT E|20|Q E|20|K silent|CTG>CTC|L|18 silent|CTG>CTA|L|18 TAF14 TATA binding protein-Associated Factor 244.0 0 0 0 0 0.923349654003907 P35189 0.956179976463318 0.9475290179252625 0.14770212769508362 1.0 0.07266800105571747 -0.399181991815567 47.66095876833174 40.0 1.0 no 14759 chrXVI_305457r 36141 high_effect YPL129W 57 - TTCTCTACTGGTGGCACTTC E|25|D silent|GAG>GAA|E|25 E|25|Q E|25|K TAF14 TATA binding protein-Associated Factor 244.0 0 0 0 0 -0.8656723525178771 P35189 0.94931298494339 0.956179976463318 0.9475290179252625 0.035726845264434814 0.020565925166010857 0.01970040611922741 0.031058000400662426 -0.056575998663902276 -0.5504559874534607 53.3993966042093 50.0 1.0 no 14760 chrXVI_305484r 36143 high_effect YPL129W 84 - TCTATACTCCATTGACGAAC E|35|Q E|35|K S|33|T S|33|N TAF14 TATA binding protein-Associated Factor 244.0 0 0 0 0 0.5607321004365902 P35189 0.956179976463318 0.9475290179252625 0.9512869715690612 0.9536849856376648 0.06132083013653755 0.3052925765514374 0.28981828689575195 0.12295201420783995 -0.5237100124359131 -0.8626520037651062 -0.4694240093231201 2.622299909591675 42.686204220226394 40.0 1.0 no 14761 chrXVI_305581 36147 high_effect YPL129W 178 + CAACTTTCGCCAATCCTAAC T|61|S T|61|I TAF14 TATA binding protein-Associated Factor 244.0 0 0 0 0 0.48738691477607204 P35189 0.9491789937019348 0.9472420215606691 1.0 0.005111179780215025 -0.5720779895782471 -1.1210880279541016 46.151207590442475 45.0 1.0 no 14762 chrXVI_305784 36150 high_effect YPL129W 381 + ACAGAAGAACTTGCGAAAAG T|128|R T|128|I TAF14 TATA binding protein-Associated Factor 244.0 0 0 0 0 0.8365672671957097 P35189 0.9476869702339172 0.9472420215606691 0.1163940131664276 0.4932710230350494 -1.4866800308227541 -1.882017970085144 35.79059564356231 40.0 1.0 no 14763 chrXVI_305864 36154 high_effect YPL129W 461 + GAACACAACTGCAGAACCAA N|155|K silent|AAC>AAT|N|155 T|156|R T|156|I TAF14 TATA binding protein-Associated Factor 244.0 0 1 0 0 0.4220522876530864 P35189 0.9439849853515624 0.9476869702339172 0.9472420215606691 0.9319618344306946 0.4777418971061706 0.1673194169998169 42.249558789311784 45.0 1.0 no 14764 chrXVI_305880r 36155 high_effect YPL129W 480 - GTCTTAGCTCTCTTCGCCTT K|166|N silent|AAG>AAA|K|166 TAF14 TATA binding protein-Associated Factor 244.0 0 1 0 0 0.18552897771113944 P35189 0.9355990290641784 0.4134851396083832 58.60836233043921 50.0 1.0 no 14765 chrXVI_307017r 36159 essential YPL128C 1182 + AGCAACAATAATGGTAGTAT S|395|R silent|AGC>AGT|S|395 N|396|K silent|AAC>AAT|N|396 TBF1 TTAGGG repeat-Binding Factor 562.0 0 0 0 0 -0.783564935227446 Q02457 0.9417110085487366 0.9439849853515624 0.588657021522522 0.983784317970276 37.437258615143264 30.0 0.0 no 14766 chrXVI_307111r 36163 essential YPL128C 1088 + CGCTATCACACAATCCATTG A|364|G A|364|V I|365|M silent|ATC>ATT|I|365 TBF1 TTAGGG repeat-Binding Factor 562.0 0 0 0 0 0.5390840883014842 Q02457 0.9484469890594482 0.9504740238189696 0.9598389863967896 0.37239235639572144 0.3312206268310547 0.11104384809732436 45.957064373991955 45.0 0.0 no 14767 chrXVI_307210 36167 essential YPL128C 992 - ACGCACTGCTTGGCTGATTT A|337|P A|337|T silent|GCG>GCC|A|337 silent|GCG>GCA|A|337 TBF1 TTAGGG repeat-Binding Factor 562.0 0 0 0 0 -0.12437214445750785 Q02457 0.9573720097541808 0.9523990154266356 0.3817005753517151 0.7611595988273621 53.3261911007092 50.0 0.0 no 14768 chrXVI_307259r 36168 essential YPL128C 940 + CTCAAGTACTCTTTTCTACA Q|315|E Q|315|* TBF1 TTAGGG repeat-Binding Factor 562.0 0 0 0 0 0.06290816089575069 Q02457 0.9590039849281312 0.6996922492980957 43.65361690983457 35.0 0.0 no 14769 chrXVI_307260 36169 essential YPL128C 942 - CCTGTAGAAAAGAGTACTTG G|321|R G|321|R TBF1 TTAGGG repeat-Binding Factor 562.0 0 0 0 0 1.3392364752689172 Q02457 0.941340982913971 0.941340982913971 0.0911998450756073 0.0911998450756073 39.50323798089522 40.0 0.0 no 14770 chrXVI_307400r 36175 essential YPL128C 799 + CTCTGACCCAGAGCTACGAA L|268|V silent|CTG>TTG|L|268 T|269|S T|269|I TBF1 TTAGGG repeat-Binding Factor 562.0 0 0 0 0 -2.165097172046273 Q02457 0.9512209892272948 0.9491789937019348 0.9472420215606691 0.05584979057312012 0.16311869025230408 0.7174111604690552 51.69859603922794 55.00000000000001 0.0 yes 14771 chrXVI_307473 36177 essential YPL128C 729 - TCGACGAAGTCCTTCTCCGA E|250|Q E|250|K V|249|L V|249|I TBF1 TTAGGG repeat-Binding Factor 562.0 0 0 0 0 0.26743669494457273 Q02457 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.4398684203624725 0.7653266787528992 0.09483810514211656 1.0 52.93814738580511 55.00000000000001 0.0 no 14772 chrXVI_307483r 36178 essential YPL128C 716 + ACTTTTGACTCCATCGGAGA L|240|V L|240|F TBF1 TTAGGG repeat-Binding Factor 562.0 0 1 0 0 -0.009267683576010792 Q02457 0.9512209892272948 0.9587849974632264 0.28353580832481384 0.052608530968427665 48.937145630169475 45.0 0.0 no 14773 chrXVI_307694 36181 essential YPL128C 508 - AAACTTTCCGCTTTGTTCCA K|175|N silent|AAG>AAA|K|175 TBF1 TTAGGG repeat-Binding Factor 562.0 0 0 0 0 -0.4526882710604568 Q02457 0.9355990290641784 0.01632905751466751 49.687724360444975 40.0 0.0 no 14774 chrXVI_307701r 36182 essential YPL128C 498 + AACAACTCCCTGGAACAAAG N|167|K silent|AAC>AAT|N|167 N|168|K silent|AAC>AAT|N|168 TBF1 TTAGGG repeat-Binding Factor 562.0 0 0 0 0 0.8319301331497431 Q02457 0.9439849853515624 0.9439849853515624 0.9248819351196288 0.9230526089668274 41.93011310561332 45.0 0.0 no 14775 chrXVI_307725r 36185 essential YPL128C 474 + TGTCCAAATACAAACACTGT P|160|A P|160|S P|160|R P|160|L TBF1 TTAGGG repeat-Binding Factor 562.0 0 0 0 0 0.5079580529032305 Q02457 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.0 0.0 0.0 0.0 39.9161432286985 35.0 0.0 no 14776 chrXVI_307784r 36186 essential YPL128C 415 + CGCTGAACTGCCTTAATTAC L|140|V silent|CTG>TTG|L|140 TBF1 TTAGGG repeat-Binding Factor 562.0 0 0 0 0 0.4827088682316191 Q02457 0.9512209892272948 0.041361834853887565 45.450678783718395 45.0 0.0 no 14777 chrXVI_307785r 36187 essential YPL128C 414 + TCGCTGAACTGCCTTAATTA L|140|V silent|CTG>TTG|L|140 S|139|W S|139|L TBF1 TTAGGG repeat-Binding Factor 562.0 0 0 0 0 -0.17392853086013854 Q02457 0.9512209892272948 0.9288619756698608 0.9298099875450134 0.041361834853887565 0.030993083491921425 0.5444786548614502 45.96869849732235 40.0 0.0 no 14778 chrXVI_307823 36188 essential YPL128C 379 - TAGCAGATTCGCCTTTCTTA silent|CTG>CTC|L|132 silent|CTG>CTA|L|132 TBF1 TTAGGG repeat-Binding Factor 562.0 0 0 0 0 0.4161129595510048 Q02457 49.91459829402515 40.0 0.0 no 14779 chrXVI_307920 36198 essential YPL128C 282 - ACGTCGTGAACAGACAGTAA V|101|L V|101|M D|100|H D|100|N TBF1 TTAGGG repeat-Binding Factor 562.0 0 0 0 0 -0.15525816275525967 Q02457 0.9539830088615416 0.9587630033493042 0.9486550092697144 0.956179976463318 0.05631134286522865 0.010793185792863369 0.014220207929611206 0.18325175344944 43.21767761155086 45.0 0.0 no 14780 chrXVI_308002 36200 essential YPL128C 200 - TTTCTGTTTCGCCTGAGCTT E|73|Q E|73|K TBF1 TTAGGG repeat-Binding Factor 562.0 0 0 0 0 -0.0965686587089497 Q02457 0.956179976463318 0.9475290179252625 0.1876852959394455 0.4111277461051941 54.51428623432105 45.0 0.0 no 14781 chrXVI_308040 36203 essential YPL128C 162 - GTCAAAACCGCTATAATATT L|60|F silent|TTG>TTA|L|60 TBF1 TTAGGG repeat-Binding Factor 562.0 0 0 0 0 0.009033609169016129 Q02457 0.9587849974632264 0.09119609743356703 38.24162580310161 30.0 0.0 no 14782 chrXVI_308039 36204 essential YPL128C 163 - CGTCAAAACCGCTATAATAT L|60|F silent|TTG>TTA|L|60 TBF1 TTAGGG repeat-Binding Factor 562.0 0 0 0 0 0.13116937735507853 Q02457 0.9587849974632264 0.09119609743356703 39.34753005294169 35.0 0.0 no 14783 chrXVI_308047r 36206 essential YPL128C 152 + CAACTCTCCCAATATTATAG N|52|K silent|AAC>AAT|N|52 S|53|C S|53|F TBF1 TTAGGG repeat-Binding Factor 562.0 0 0 0 0 0.7558050311978438 Q02457 0.9439849853515624 0.945252001285553 0.9294660091400146 0.7076998353004456 0.05645029246807098 0.07443181425333023 41.352781733595634 35.0 0.0 no 14784 chrXVI_308137 36208 essential YPL128C 65 - TCAACCTAGTTCTTGCAGGC L|28|F silent|TTG>TTA|L|28 R|27|S silent|AGG>AGA|R|27 TBF1 TTAGGG repeat-Binding Factor 562.0 0 0 0 0 0.0672038344548413 Q02457 0.9587849974632264 0.9087679982185364 0.0 0.17304226756095886 52.947289275770224 50.0 0.0 no 14785 chrXVI_310240 36209 essential YPL126W 30 + AAACTGTCAGTCGTATCTGG L|12|V silent|CTG>TTG|L|12 NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 -0.3140839951312802 Q02931 0.9512209892272948 0.212463453412056 45.2389733690074 45.0 1.0 no 14786 chrXVI_310348r 36214 essential YPL126W 141 - ACCTTGATCTGATTGTTAAA K|53|N silent|AAG>AAA|K|53 V|54|L V|54|M NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 0.4635771775672744 Q02931 0.9355990290641784 0.9539830088615416 0.9587630033493042 0.11530031263828278 0.07943353801965714 0.015004359185695646 40.343064115258926 30.0 1.0 no 14787 chrXVI_310433r 36215 essential YPL126W 226 - TTCTTCTTGCAGAAATATTC E|82|Q E|82|K E|81|Q E|81|K NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 0.1821229269358876 Q02931 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.4989871084690094 0.7554823160171509 39.334399523436154 30.0 1.0 no 14788 chrXVI_310467 36216 essential YPL126W 257 + ATCGATTGTAAAGATTCTGC S|87|W S|87|L NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 -0.262083621374618 Q02931 0.9288619756698608 0.9298099875450134 0.19090470671653748 0.7859394550323486 39.878884887299755 35.0 1.0 no 14789 chrXVI_310541r 36218 essential YPL126W 334 - AACAATTACATGACCATTAT V|118|L V|118|I NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 0.3314160307538723 Q02931 0.9539830088615416 0.9574310183525084 0.08088964223861694 0.32631054520606995 36.56581239605208 25.0 1.0 no 14790 chrXVI_310633 36220 essential YPL126W 423 + GCAAATGTTTTCCATAGCGA A|142|G A|142|V NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 0.04256252537153335 Q02931 0.9484469890594482 0.9504740238189696 0.0742684006690979 0.6408700942993164 46.099551841546706 40.0 1.0 no 14791 chrXVI_310644r 36221 essential YPL126W 437 - TTCTATAGTTGCCCTCGCTA R|152|T R|152|K NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 0.005301126119771196 Q02931 0.932735025882721 0.955805003643036 0.3991729617118835 0.34195417165756226 54.50224654188719 45.0 1.0 no 14792 chrXVI_310677 36222 essential YPL126W 467 + GTTCAAGGACCCTAGTCAAA F|157|L silent|TTC>TTT|F|157 NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 0.02707034962478294 Q02931 0.9387490153312684 0.8243253827095032 47.63460349734169 45.0 1.0 no 14793 chrXVI_310739r 36223 essential YPL126W 532 - TTGCTTTTTAGCATCGTCAA K|183|N silent|AAG>AAA|K|183 NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 0.7461452289653188 Q02931 0.9355990290641784 0.5381475687026978 46.000211102050905 35.0 1.0 no 14794 chrXVI_310749 36224 essential YPL126W 539 + TGCTAAAAAGCAATTTGAAG A|181|G A|181|V NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 -0.4799968047843569 Q02931 0.9484469890594482 0.9504740238189696 0.4193011522293091 0.2854454815387726 33.205877391879085 30.0 1.0 no 14795 chrXVI_310817r 36226 essential YPL126W 610 - ATGCGCTAGCAGTTTACCAT silent|GCG>GCC|A|209 silent|GCG>GCA|A|209 A|209|P A|209|T NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 -1.1605419810019852 Q02931 0.9573720097541808 0.9523990154266356 0.13742667436599731 0.2865774631500244 52.19082870439513 45.0 1.0 no 14796 chrXVI_310958 36227 essential YPL126W 748 + AATCCCTATCCTATAACACA S|251|C S|251|F silent|TCC>TCG|S|251 silent|TCC>TCT|S|251 NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 -0.00039850036078137313 Q02931 0.945252001285553 0.9294660091400146 0.12043126672506332 0.1127832755446434 45.12921212055347 35.0 1.0 no 14797 chrXVI_310974 36228 essential YPL126W 764 + CACAAGGTACGTTTCTAGCA T|256|R T|256|I NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 -0.8947291767266684 Q02931 0.9476869702339172 0.9472420215606691 0.01638457179069519 0.01587874256074429 47.22768630221043 45.0 1.0 no 14798 chrXVI_311039r 36233 essential YPL126W 832 - GCTTACGATACTTATAACTC S|284|T S|284|N V|283|L V|283|I NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 -0.5051541496348697 Q02931 0.9512869715690612 0.9536849856376648 0.9539830088615416 0.9574310183525084 0.4990511536598206 1.0 0.3289346396923065 0.6591317057609558 39.96288173023692 35.0 1.0 no 14799 chrXVI_311066r 36235 essential YPL126W 859 - GAGCAGTCTTATTTGTAGAT silent|CTG>CTC|L|292 silent|CTG>CTA|L|292 NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 -0.10432203131637337 Q02931 44.27596676451316 35.0 1.0 no 14800 chrXVI_311072 36236 essential YPL126W 862 + TACAAATAAGACTGCTCAAA Q|289|E Q|289|* NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 0.3233492610149889 Q02931 0.9590039849281312 1.0 34.56723382828892 30.0 1.0 no 14801 chrXVI_311138r 36238 essential YPL126W 931 - CCAACCACCAGATAGCAAAT W|317|S W|317|* G|316|A G|316|D NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 -0.1582914598912837 Q02931 0.8858469724655151 0.9499930143356324 0.9446240067481996 0.025970185175538063 0.0 0.0 46.51237708741184 45.0 1.0 no 14802 chrXVI_311347 36242 essential YPL126W 1137 + ACCTCCAAATTGTCGATTAA silent|ACC>ACG|T|380 silent|ACC>ACT|T|380 T|380|S T|380|I NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 0.7184678861938434 Q02931 0.9491789937019348 0.9472420215606691 0.8672747611999512 0.5764604210853577 42.96713260271076 35.0 1.0 no 14803 chrXVI_311348r 36244 essential YPL126W 1141 - CCCGTTAATCGACAATTTGG G|387|R G|387|R G|387|A G|387|E NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 -0.8664292170119214 Q02931 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.05639427155256273 0.05639427155256273 0.3112639784812927 0.07620638608932495 45.32096941621876 45.0 1.0 no 14804 chrXVI_311400 36247 essential YPL126W 1190 + ACACATTCAGCAACCAATCT H|398|Q silent|CAC>CAT|H|398 H|398|D H|398|Y NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 -0.6339322109369823 Q02931 0.9588389992713928 0.9473130106925964 0.9489949941635132 0.22271564602851868 1.0 0.10138163715600967 45.638503091014854 40.0 1.0 no 14805 chrXVI_311453r 36248 essential YPL126W 1246 - CTTCTTAGAGTGATTGAGAG K|421|N silent|AAG>AAA|K|421 NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 0.9729306963931889 Q02931 0.9355990290641784 0.4961410164833069 41.4248764906348 40.0 1.0 no 14806 chrXVI_311614 36249 essential YPL126W 1404 + AACTATCAGTATTTAACATC N|469|K silent|AAC>AAT|N|469 Q|471|E Q|471|* NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 0.032770718094172466 Q02931 0.9439849853515624 0.9590039849281312 0.5657064318656921 0.0 34.7849083257708 25.0 1.0 no 14807 chrXVI_311685r 36250 essential YPL126W 1478 - ACTTCAAATCAGTTATTATT K|499|N silent|AAG>AAA|K|499 L|498|F silent|TTG>TTA|L|498 NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 -0.06496390777526093 Q02931 0.9355990290641784 0.9587849974632264 0.03170124813914299 0.2039208710193634 35.40028010178793 20.0 1.0 no 14808 chrXVI_311686r 36251 essential YPL126W 1479 - AACTTCAAATCAGTTATTAT K|499|N silent|AAG>AAA|K|499 L|498|F silent|TTG>TTA|L|498 NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 -0.26578430913862505 Q02931 0.9355990290641784 0.9587849974632264 0.03170124813914299 0.2039208710193634 33.89712988409934 20.0 1.0 no 14809 chrXVI_311711r 36252 essential YPL126W 1504 - AATCATCCATTGCCCATCTT M|507|I M|507|I W|506|C W|506|* NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 -0.69597815769799 Q02931 0.9553959965705872 0.9553959965705872 0.8858469724655151 0.0793844684958458 0.0793844684958458 0.02813613973557949 51.86139902420837 40.0 1.0 no 14810 chrXVI_311783 36253 essential YPL126W 1573 + TAACTCATATCTTGAAATTT T|526|S T|526|I H|527|D H|527|Y NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 0.4609144726385389 Q02931 0.9491789937019348 0.9472420215606691 0.9473130106925964 0.9489949941635132 0.8961001634597778 0.48954162001609797 0.034427233040332794 0.7213592529296875 33.298899371803714 20.0 1.0 no 14811 chrXVI_311842 36254 essential YPL126W 1632 + ACGAAAGTAATAAATCCACA T|545|R T|545|M NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 0.7478185749086594 Q02931 0.9476869702339172 0.9502379894256592 0.0 0.0 35.263549095080855 30.0 1.0 no 14812 chrXVI_311899r 36256 essential YPL126W 1692 - TGACTATTATTAACTGATCT S|570|T S|570|N NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 -1.5848756840228797 Q02931 0.9512869715690612 0.9536849856376648 0.18847106397151947 0.6637034416198729 36.28186143208977 25.0 1.0 no 14813 chrXVI_311969 36258 essential YPL126W 1759 + TCGACTCTCATGAGAGCAAC F|587|L silent|TTC>TTT|F|587 D|588|E silent|GAC>GAT|D|588 NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 -0.7952166833134375 Q02931 0.9387490153312684 0.9532920122146606 0.6113083958625793 0.619260311126709 46.44485138781846 50.0 1.0 no 14814 chrXVI_312078r 36259 essential YPL126W 1871 - GCAACTTGTCATCGAAACCA L|630|F silent|TTG>TTA|L|630 K|629|N silent|AAG>AAA|K|629 NAN1 Net1 Associated Nuclear protein 896.0 0 0 0 0 0.08974898204051518 Q02931 0.9587849974632264 0.9355990290641784 0.039530694484710686 0.13863974809646604 45.87681744451993 45.0 1.0 no 14815 chrXVI_316783r 36260 essential YPL124W 31 - ATCGTCTTGAAACTTTTTAC D|17|H D|17|N D|16|H D|16|N 0 1 0 0 0.0567037951155755 P33419 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 38.475088787728055 30.0 1.0 no 14816 chrXVI_316935 36262 essential YPL124W 180 + TTACATAGATTGTCTCCCAC H|62|D H|62|Y 0 1 0 0 -0.2800357490216402 P33419 0.9473130106925964 0.9489949941635132 47.50244525325445 40.0 1.0 no 14817 chrXVI_316951r 36264 essential YPL124W 199 - CCTATCGTCTGATTTACCTG R|73|T R|73|K D|72|H D|72|N 0 1 0 0 -0.5715546680240553 P33419 0.932735025882721 0.955805003643036 0.9486550092697144 0.956179976463318 49.07791699614682 45.0 1.0 no 14818 chrXVI_316985r 36265 essential YPL124W 233 - TCCTTAGCTTATCATCTAGC R|84|T R|84|K R|84|S silent|AGG>AGA|R|84 0 0 0 0 -0.2535464429667013 P33419 0.932735025882721 0.955805003643036 0.9087679982185364 49.475764248067996 40.0 1.0 no 14819 chrXVI_317118r 36271 essential YPL124W 366 - GCAAATTTATCAGTTCTTAC A|129|P A|129|T 0 0 0 0 0.18517931052084927 P33419 0.9573720097541808 0.9523990154266356 39.04315875930456 30.0 1.0 no 14820 chrXVI_317307 36273 essential YPL124W 552 + GAACACTCCCGCTCTTTTTC H|186|D H|186|Y H|186|Q silent|CAC>CAT|H|186 0 1 0 0 -0.08654047725289514 P33419 0.9473130106925964 0.9489949941635132 0.9588389992713928 52.98014103615021 50.0 1.0 no 14821 chrXVI_317308 36274 essential YPL124W 553 + AACACTCCCGCTCTTTTTCT H|186|D H|186|Y H|186|Q silent|CAC>CAT|H|186 0 1 0 0 -0.5686563838240749 P33419 0.9473130106925964 0.9489949941635132 0.9588389992713928 53.56638488068064 45.0 1.0 no 14822 chrXVI_319742 36275 essential YPL122C 1006 - TTCTACAATCAATGAGCCAT E|342|Q E|342|K V|341|L V|341|I 0 0 0 0 -0.2364553691234468 Q02939 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.0 0.0 1.0 0.4793818891048432 42.8669812022149 35.0 0.0 no 14823 chrXVI_319743 36276 essential YPL122C 1005 - TCTACAATCAATGAGCCATC E|342|Q E|342|K V|341|L V|341|I 0 0 0 0 -0.01541353843614246 Q02939 0.956179976463318 0.9475290179252625 0.9539830088615416 0.9574310183525084 0.0 0.0 1.0 0.4793818891048432 43.55247896565601 40.0 0.0 no 14824 chrXVI_319785r 36277 essential YPL122C 960 + TCAGATGATTTGAACAAAGC S|321|* S|321|L 0 0 0 0 -0.236482134491852 Q02939 0.9298099875450134 36.95836545319918 35.0 0.0 no 14825 chrXVI_319817 36278 essential YPL122C 931 - ATCTGTTGTGGATTTCCCGT D|317|H D|317|N 0 0 0 0 0.358544704774735 Q02939 0.9486550092697144 0.956179976463318 54.07943080742922 45.0 0.0 no 14826 chrXVI_319839 36279 essential YPL122C 909 - GCGCCGTCTTCATTTACTGA G|309|A G|309|D A|310|P A|310|T 0 0 0 0 -0.05495537726677159 Q02939 0.9499930143356324 0.9446240067481996 0.9573720097541808 0.9523990154266356 53.955262951247384 50.0 0.0 no 14827 chrXVI_319883 36281 essential YPL122C 865 - TACACTATCCATCGCATTGG V|295|L V|295|I S|294|T S|294|N 0 0 0 0 -0.6438226168913088 Q02939 0.9539830088615416 0.9574310183525084 0.9512869715690612 0.9536849856376648 0.19133338332176208 0.2309270352125168 0.5217486023902893 0.6016033291816711 47.996966268840474 45.0 0.0 no 14828 chrXVI_319966 36283 essential YPL122C 782 - TGCTATCATTTGAATGCTTC S|267|T S|267|N D|266|H D|266|N 0 0 0 0 0.7837778724032103 Q02939 0.9512869715690612 0.9536849856376648 0.9486550092697144 0.956179976463318 0.8139553070068359 0.5383771061897278 0.05833572149276733 0.3474705219268799 43.305270824170634 35.0 0.0 no 14829 chrXVI_320313r 36288 essential YPL122C 432 + ACAATATTACATTTCATGGT T|145|R T|145|I 0 0 0 0 0.4157806655041199 Q02939 0.9476869702339172 0.9472420215606691 0.4396575093269348 0.15896250307559967 38.09370348837263 25.0 0.0 no 14830 chrXVI_320389r 36289 essential YPL122C 356 + CTCATTCGGTGTGGTTGTAG S|120|* S|120|L F|121|L silent|TTC>TTT|F|121 0 0 0 0 -2.103487454672756 Q02939 0.9298099875450134 0.9387490153312684 0.0036485276650637393 0.07371537387371062 50.918902960605976 50.0 0.0 yes 14831 chrXVI_320441r 36291 essential YPL122C 304 + CAACATTCAAAATCAGCCTG T|103|R T|103|I 0 0 0 0 0.24269515344504644 Q02939 0.9476869702339172 0.9472420215606691 0.5601837635040283 0.2601402997970581 40.784150573503496 40.0 0.0 no 14832 chrXVI_320731 36294 essential YPL122C 17 - ACTGAGTGACCGAATGCTTC Q|12|H silent|CAG>CAA|Q|12 0 0 0 0 1.2282042130870476 Q02939 0.9570760130882264 0.02331633493304253 48.30306504334226 50.0 0.0 no 14833 chrXVI_328076 36296 essential YPL117C 635 - TAGCGTTGATCTTATAAAAT A|218|P A|218|T IDI1 Isopentenyl Diphosphate Isomerase 288.0 0 1 0 0 -0.25893690380879925 P15496 0.2967143654823303 0.4653452336788178 13.584799766540527 5.255199909210205 35.498483171486676 25.0 0.0 no 14834 chrXVI_328105 36297 essential YPL117C 606 - TCAATTTCATGTTCACCCCA D|209|H D|209|N IDI1 Isopentenyl Diphosphate Isomerase 288.0 0 1 0 0 -0.24935408880076915 P15496 0.0017764493823051453 0.0065081086941063395 51.026084589527734 40.0 0.0 no 14835 chrXVI_328121r 36298 essential YPL117C 587 + GGCACCAAGCAATGAACCAT A|197|G A|197|V P|198|A P|198|S IDI1 Isopentenyl Diphosphate Isomerase 288.0 0 0 0 0 -0.4550686560003106 P15496 0.08858564496040344 0.004878253675997257 0.18722307682037356 0.03906714543700218 1.2201999425888062 0.7771999835968018 48.96527689470634 50.0 0.0 no 14836 chrXVI_328122r 36299 essential YPL117C 586 + TGGCACCAAGCAATGAACCA A|197|G A|197|V P|198|A P|198|S IDI1 Isopentenyl Diphosphate Isomerase 288.0 0 0 0 0 -0.6161180489478435 P15496 0.08858564496040344 0.004878253675997257 0.18722307682037356 0.03906714543700218 1.2201999425888062 0.7771999835968018 48.950012230856494 50.0 0.0 no 14837 chrXVI_328549r 36302 essential YPL117C 159 + AGCGGAGAAACATGTTTTTC S|54|R silent|AGC>AGT|S|54 IDI1 Isopentenyl Diphosphate Isomerase 288.0 0 1 0 0 0.9694327365079056 P15496 0.578398585319519 42.35313143082488 40.0 0.0 no 14838 chrXVI_328636 36304 essential YPL117C 75 - AACTCTTCCAAAATGTCTTC E|31|D silent|GAG>GAA|E|31 E|31|Q E|31|K IDI1 Isopentenyl Diphosphate Isomerase 288.0 0 0 0 0 -0.02748922601730269 P15496 0.6154837012290955 0.619376540184021 0.9986764192581176 41.23746469650394 35.0 0.0 no 14839 chrXVI_328643 36305 essential YPL117C 68 - CCAAAATGTCTTCAGGTGTT L|29|F silent|TTG>TTA|L|29 IDI1 Isopentenyl Diphosphate Isomerase 288.0 0 1 0 0 0.6919906862520482 P15496 0.17011658847332 45.448533241364714 40.0 0.0 no 14840 chrXVI_328699r 36307 essential YPL117C 9 + GACAACAATAGTATGCCCCA D|4|E silent|GAC>GAT|D|4 N|5|K silent|AAC>AAT|N|5 IDI1 Isopentenyl Diphosphate Isomerase 288.0 0 1 0 0 0.25799628452379364 P15496 48.548471114953664 45.0 0.0 no 14841 chrXVI_370054 36308 essential YPL094C 590 - AAACATATAATATCAATCTC V|203|L V|203|I SEC62 SECretory 274.0 0 0 0 0 0.15123514377529246 P21825 0.9539830088615416 0.9574310183525084 0.479133665561676 1.0 30.136721288075194 20.0 0.0 no 14842 chrXVI_370143 36314 essential YPL094C 501 - CTCATGGAGCGCGGCCACAA M|173|I M|173|I SEC62 SECretory 274.0 0 0 0 0 0.3504120718248557 P21825 0.9553959965705872 0.9553959965705872 0.04634664580225945 0.04634664580225945 57.01222975550456 65.0 0.0 no 14843 chrXVI_370169 36317 essential YPL094C 475 - GCATACGAGCGCCAATATGA C|165|S C|165|Y V|164|L V|164|I SEC62 SECretory 274.0 0 0 0 0 -1.1621766390200363 P21825 0.9421560168266296 0.9290120005607604 0.9539830088615416 0.9574310183525084 0.013828111812472343 0.013133727945387363 0.07103200256824492 1.0 48.92940492065321 50.0 0.0 no 14844 chrXVI_370241 36319 essential YPL094C 403 - GTTCCAAACAAAGTATTCAT W|140|C W|140|* W|140|S W|140|* SEC62 SECretory 274.0 0 0 0 0 0.26687884912460474 P21825 0.8858469724655151 0.8858469724655151 0.0 0.0 38.66510148246397 30.0 0.0 no 14845 chrXVI_370369r 36321 essential YPL094C 272 + TCAACTTATAAAGGCACAAA Q|92|E Q|92|* L|93|V L|93|F SEC62 SECretory 274.0 0 0 0 0 -0.012794594325039349 P21825 0.9590039849281312 0.9512209892272948 0.9587849974632264 0.06324989348649979 0.020301761105656624 0.019200081005692482 35.44536202740233 30.0 0.0 no 14846 chrXVI_370378r 36322 essential YPL094C 263 + AATCTTTATTCAACTTATAA I|89|M silent|ATC>ATT|I|89 SEC62 SECretory 274.0 0 0 0 0 0.4577974366780078 P21825 0.9598389863967896 0.03867902234196663 31.76029850651417 15.0 0.0 no 14847 chrXVI_370501 36324 essential YPL094C 143 - CCCTAACAAATCTCTTGTAA R|54|T R|54|K R|54|S silent|AGG>AGA|R|54 SEC62 SECretory 274.0 0 0 0 0 -0.5877925915679028 P21825 0.932735025882721 0.955805003643036 0.9087679982185364 0.0 0.0 0.0 41.888340723189174 35.0 0.0 no 14848 chrXVI_370501r 36326 essential YPL094C 140 + CCGTTACAAGAGATTTGTTA R|48|G R|48|C Y|49|* silent|TAC>TAT|Y|49 SEC62 SECretory 274.0 0 0 0 0 -0.4276201629829125 P21825 0.8994590044021606 0.8926740288734436 0.0 0.0 42.110532198811995 35.0 0.0 no 14849 chrXVI_370573r 36330 essential YPL094C 68 + TACTCTTTTACGCAACCATA T|24|S T|24|I L|25|V L|25|F SEC62 SECretory 274.0 0 0 0 0 0.18313874492823198 P21825 0.9491789937019348 0.9472420215606691 0.9512209892272948 0.9587849974632264 0.8017122745513916 0.18575847148895264 0.32361510396003723 0.7458856105804443 44.16211532571907 35.0 0.0 no 14850 chrXVI_370634 36332 essential YPL094C 10 - TGCATTGCTACCTGGACCTA A|10|P A|10|T SEC62 SECretory 274.0 0 0 0 0 -0.3275791673276939 P21825 0.9573720097541808 0.9523990154266356 0.3557647168636322 0.5823531746864319 54.44990586951377 50.0 0.0 no 14851 chrXVI_371002r 36333 essential YPL093W 27 - TCATTTGCTGGAGCGACAGT D|16|H D|16|N NOG1 NucleOlar G-protein 647.0 0 0 0 0 -0.29692818552943306 Q02892 0.0061700642108917245 0.011131305247545242 51.751633273177326 50.0 1.0 no 14852 chrXVI_371051r 36334 essential YPL093W 76 - CACAGTTGGTGTCTTTCTCT V|32|L V|32|M NOG1 NucleOlar G-protein 647.0 0 0 0 0 -0.31324055991104593 Q02892 0.15765415132045746 0.03711719438433647 52.443574271614295 45.0 1.0 no 14853 chrXVI_371052r 36335 essential YPL093W 77 - TCACAGTTGGTGTCTTTCTC V|32|L V|32|M silent|GTG>GTC|V|32 silent|GTG>GTA|V|32 NOG1 NucleOlar G-protein 647.0 0 0 0 0 -1.1144833960459544 Q02892 0.15765415132045746 0.03711719438433647 51.65822710773853 45.0 1.0 no 14854 chrXVI_371080r 36338 essential YPL093W 105 - ATTCTTGTAATCTTGAAACC R|41|T R|41|K NOG1 NucleOlar G-protein 647.0 0 0 0 0 0.2547808897240317 Q02892 0.0034058133605867624 0.04675164818763733 38.65250093250523 30.0 1.0 no 14855 chrXVI_371130 36339 essential YPL093W 152 + ATACACAGGTGAAGGTTTCG Y|52|* silent|TAC>TAT|Y|52 T|53|R T|53|I NOG1 NucleOlar G-protein 647.0 0 0 0 0 -1.1643884475333652 Q02892 0.03971567004919052 0.3473625183105469 44.572835647423226 45.0 1.0 no 14856 chrXVI_371202 36340 essential YPL093W 224 + TCCTTTCCATAGAGATTTGA P|76|R P|76|L P|76|A P|76|S NOG1 NucleOlar G-protein 647.0 0 0 0 0 -0.25904758441507136 Q02892 0.0 0.0 0.0 0.0 46.28305010864147 35.0 1.0 no 14857 chrXVI_371203r 36341 essential YPL093W 228 - TCCATCAAATCTCTATGGAA M|82|I M|82|I D|83|H D|83|N NOG1 NucleOlar G-protein 647.0 0 0 0 0 0.16623340041408668 Q02892 0.38164931535720825 0.38164931535720825 0.15509359538555145 1.0 41.83772319330893 35.0 1.0 no 14858 chrXVI_371285r 36343 essential YPL093W 310 - TCTGGCGACTTGTTCCACAA R|110|T R|110|K A|109|P A|109|T NOG1 NucleOlar G-protein 647.0 0 0 0 0 0.9741978661674916 Q02892 0.01036207377910614 1.0 0.03686168789863586 0.026617594063282013 52.00516895365121 50.0 1.0 no 14859 chrXVI_371286r 36344 essential YPL093W 311 - CTCTGGCGACTTGTTCCACA R|110|T R|110|K A|109|P A|109|T NOG1 NucleOlar G-protein 647.0 0 0 0 0 -0.7655756197869941 Q02892 0.01036207377910614 1.0 0.03686168789863586 0.026617594063282013 55.530680206795175 55.00000000000001 1.0 no 14860 chrXVI_371388 36346 essential YPL093W 410 + AACTATAGTCAAGAAATTGA T|138|S T|138|I NOG1 NucleOlar G-protein 647.0 0 0 0 0 -0.2649319678154117 Q02892 0.030846996232867237 0.0041482243686914435 32.491428346091425 25.0 1.0 no 14861 chrXVI_371413r 36349 essential YPL093W 438 - ACTTGTTCCAAATAGGCCAA V|153|L V|153|I NOG1 NucleOlar G-protein 647.0 0 0 0 0 -0.16399540652742198 Q02892 0.012672778218984604 0.08709858357906343 46.691298447868064 40.0 1.0 no 14862 chrXVI_371469r 36350 essential YPL093W 494 - TCAGCAAGGTTCTGGTATTT silent|CTG>CTC|L|171 silent|CTG>CTA|L|171 L|170|F silent|TTG>TTA|L|170 NOG1 NucleOlar G-protein 647.0 0 0 0 0 -0.3355340256853263 Q02892 0.007307956926524639 48.22232080113429 40.0 1.0 no 14863 chrXVI_371575 36353 essential YPL093W 597 + ACAACCAAGAGTTTATACGT T|200|R T|200|I T|201|S T|201|I NOG1 NucleOlar G-protein 647.0 0 0 0 0 -0.613911970129127 Q02892 0.0 0.0 0.0 0.0 41.19167563994762 35.0 1.0 no 14864 chrXVI_371718 36358 essential YPL093W 740 + TTCTTGTGTTTTGTACTTCA S|248|C S|248|F NOG1 NucleOlar G-protein 647.0 0 0 0 0 0.576501363798669 Q02892 0.004749063868075609 0.00184043834451586 45.22843953438185 30.0 1.0 no 14865 chrXVI_371808 36360 essential YPL093W 830 + ATTCGCCAACAAGTCTGTCA F|278|L silent|TTC>TTT|F|278 A|279|G A|279|V NOG1 NucleOlar G-protein 647.0 0 1 0 0 -0.1408776113602446 Q02892 0.0 0.25630587339401245 0.3209846913814545 49.34660491969277 45.0 1.0 no 14866 chrXVI_371813r 36361 essential YPL093W 838 - AACAACCATGACAGACTTGT V|286|L V|286|I V|285|L V|285|I NOG1 NucleOlar G-protein 647.0 0 0 0 0 -0.12549931245915494 Q02892 0.12696078419685364 0.37108340859413147 0.373851090669632 0.6263699531555176 42.911358764066456 40.0 1.0 no 14867 chrXVI_371860r 36362 essential YPL093W 885 - CGCTCTTCGTCTAAATCCTC E|301|D silent|GAG>GAA|E|301 E|301|Q E|301|K NOG1 NucleOlar G-protein 647.0 0 0 0 0 -1.052560829517522 Q02892 0.254324734210968 0.05918179079890251 0.02498108148574829 50.433089674785045 50.0 1.0 no 14868 chrXVI_371943r 36363 essential YPL093W 968 - CCATAACGTTTTCTTCCAGT M|329|I M|329|I V|328|L V|328|I NOG1 NucleOlar G-protein 647.0 0 0 0 0 0.4859023298050863 Q02892 0.22216397523880005 0.22216397523880005 0.11793815344572067 0.19848206639289856 49.00904040724521 40.0 1.0 no 14869 chrXVI_372112r 36364 essential YPL093W 1137 - TTCAAATTCTTGACAGATTC L|385|F silent|TTG>TTA|L|385 NOG1 NucleOlar G-protein 647.0 0 1 0 0 0.07867534622706641 Q02892 0.2657741904258728 37.459202215938255 30.0 1.0 no 14870 chrXVI_372145r 36366 essential YPL093W 1170 - TTTCTCCTGTTTGGATCTTC R|396|T R|396|K R|395|S silent|AGG>AGA|R|395 NOG1 NucleOlar G-protein 647.0 0 0 0 0 -0.7379213736579779 Q02892 0.09915898740291597 0.5482684969902039 0.11005685478448868 50.427134895407285 40.0 1.0 no 14871 chrXVI_372207 36367 essential YPL093W 1229 + TGTCTTCAATGTTAACTTGA silent|GTC>GTG|V|411 silent|GTC>GTT|V|411 F|412|L silent|TTC>TTT|F|412 NOG1 NucleOlar G-protein 647.0 0 0 0 0 0.17811393742617482 Q02892 0.014623625203967094 39.90104585072169 30.0 1.0 no 14872 chrXVI_372237r 36368 essential YPL093W 1262 - TCCACTCATCATCTTCTAAT W|427|S W|427|* W|427|C W|427|* NOG1 NucleOlar G-protein 647.0 0 0 0 0 -1.2747973715689795 Q02892 0.15881912410259247 0.0500766895711422 46.056580639133976 35.0 1.0 no 14873 chrXVI_372268 36369 essential YPL093W 1290 + ATCATGCCAGAAATCTTGGA I|431|M silent|ATC>ATT|I|431 P|433|A P|433|S NOG1 NucleOlar G-protein 647.0 0 0 0 0 0.8820082840669375 Q02892 0.09077119082212448 0.0 0.0 45.1849494913866 40.0 1.0 no 14874 chrXVI_375554r 36372 no_effect YPL091W 55 - ATCGTAATGCTTGGTGTTCG D|25|H D|25|N GLR1 GLutathione Reductase 483.0 0 0 0 0 0.9944378563402234 P41921 0.9486550092697144 0.956179976463318 0.004903698340058328 0.024004267528653145 0.05550000071525574 0.3314200043678284 47.49501116973943 45.0 1.0 no 14875 chrXVI_375570 36374 no_effect YPL091W 68 + TTACGATTACCTCGTCATCG Y|24|* silent|TAC>TAT|Y|24 GLR1 GLutathione Reductase 483.0 0 0 0 0 1.212982136263265 P41921 46.73675370488303 45.0 1.0 no 14876 chrXVI_375571 36375 no_effect YPL091W 69 + TACGATTACCTCGTCATCGG Y|24|* silent|TAC>TAT|Y|24 GLR1 GLutathione Reductase 483.0 0 0 0 0 0.5678800706119761 P41921 48.72855588294937 50.0 1.0 no 14877 chrXVI_375645 36381 no_effect YPL091W 143 + GACATTACTAGTTGAAGCTA T|49|R T|49|I GLR1 GLutathione Reductase 483.0 0 0 0 0 0.055701303938896884 P41921 0.9476869702339172 0.9472420215606691 0.0048658293671906 0.10057149827480316 13.60569953918457 -0.3444199860095978 41.01707277814768 35.0 1.0 no 14878 chrXVI_375680r 36382 no_effect YPL091W 181 - AACACAACCCACGTTAACAC V|67|L V|67|I C|66|S C|66|Y GLR1 GLutathione Reductase 483.0 0 1 0 0 -0.1281280135186159 P41921 0.9539830088615416 0.9574310183525084 0.9421560168266296 0.9290120005607604 0.0 0.0 0.0 0.0 -0.7135999798774719 -0.32627999782562256 2.534359931945801 0.8992000222206116 2.041199922561645 0.4815999865531922 -0.2869099974632263 -0.2087800055742264 3.29475998878479 0.5061500072479248 43.849348007065934 45.0 1.0 no 14879 chrXVI_375703r 36383 no_effect YPL091W 204 - GCATACCACATGACTTTCTT A|75|P A|75|T W|73|C W|73|* GLR1 GLutathione Reductase 483.0 0 0 0 0 -0.41942843060442375 P41921 0.9573720097541808 0.9523990154266356 0.8858469724655151 0.027592241764068604 0.3702611029148102 0.0011434032348915935 3.9313600063323975 0.7995399832725525 2.6213600635528564 2.9331998825073238 1.7971999645233154 3.1414000988006587 8.121919631958008 3.7551898956298833 48.06394916722446 40.0 1.0 no 14880 chrXVI_375816 36384 no_effect YPL091W 314 + GCCAGAATTTAAGCAGAAAA P|106|R P|106|L P|106|A P|106|S GLR1 GLutathione Reductase 483.0 0 0 0 0 -0.27105031364544474 P41921 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.5498988032341003 0.3075167536735535 0.7804248332977295 0.7358402609825134 1.6623400449752808 1.0866199731826782 1.476940035820007 1.4816999435424805 38.57965164060789 35.0 1.0 no 14881 chrXVI_375870r 36386 no_effect YPL091W 371 - TTTCTTTTTCTAAATTCTTC E|130|Q E|130|K GLR1 GLutathione Reductase 483.0 0 1 0 0 0.3724537093768811 P41921 0.956179976463318 0.9475290179252625 0.3184676766395569 0.4613978266716003 -0.1960200071334839 -0.25619998574256897 36.66804878681802 20.0 1.0 no 14882 chrXVI_376090r 36388 no_effect YPL091W 591 - CCAACAACAACAACTTTCTT G|204|R G|204|S V|203|L V|203|I GLR1 GLutathione Reductase 483.0 0 0 0 0 0.1997508982565096 P41921 0.941340982913971 0.951104998588562 0.9539830088615416 0.9574310183525084 0.0 0.0 0.0837559625506401 0.25013068318367004 9.82211971282959 4.75924015045166 2.038739919662476 0.9510400295257568 39.934007449060346 35.0 1.0 no 14883 chrXVI_376149r 36392 no_effect YPL091W 650 - GCGTTTCGGATCCCAGCCCA silent|ACG>ACC|T|223 silent|ACG>ACA|T|223 E|222|Q E|222|K GLR1 GLutathione Reductase 483.0 0 0 0 0 -0.6448560070011401 P41921 0.956179976463318 0.9475290179252625 0.17252598702907562 0.383568674325943 0.38877999782562256 0.3352999985218048 64.2053343310385 65.0 1.0 no 14884 chrXVI_376234 36394 no_effect YPL091W 732 + ACTGACCATTACGTAAAGGA T|245|S T|245|I D|246|E silent|GAC>GAT|D|246 GLR1 GLutathione Reductase 483.0 0 0 0 0 0.7277818225870634 P41921 0.9491789937019348 0.9472420215606691 0.9532920122146606 0.07590249180793762 0.3711459338665009 1.0 2.191620111465454 2.9712800979614262 -0.34817999601364136 42.44498412739796 40.0 1.0 no 14885 chrXVI_376277r 36395 no_effect YPL091W 778 - TTTCTCCACCTTAACAATTT E|265|D silent|GAG>GAA|E|265 E|265|Q E|265|K GLR1 GLutathione Reductase 483.0 0 0 0 0 0.3862811074132629 P41921 0.94931298494339 0.956179976463318 0.9475290179252625 0.5502651333808899 0.4960142970085144 0.8335033059120178 0.6418600082397461 0.15092000365257266 0.16132000088691711 43.77260714467685 30.0 1.0 no 14886 chrXVI_376391r 36398 no_effect YPL091W 892 - TTCTGAACCCATACCTAGAT E|304|Q E|304|K GLR1 GLutathione Reductase 483.0 0 0 0 0 0.7805278671581304 P41921 0.956179976463318 0.9475290179252625 0.07716923952102661 0.10402853786945344 0.182559996843338 0.4356400072574616 47.545258939567255 40.0 1.0 no 14887 chrXVI_376392r 36399 no_effect YPL091W 893 - TTTCTGAACCCATACCTAGA E|304|Q E|304|K GLR1 GLutathione Reductase 483.0 0 0 0 0 0.5249009954762971 P41921 0.956179976463318 0.9475290179252625 0.07716923952102661 0.10402853786945344 0.182559996843338 0.4356400072574616 47.81157891528403 40.0 1.0 no 14888 chrXVI_376477 36401 no_effect YPL091W 975 + GTTCCAAACATTTATTCTCT P|327|A P|327|S P|327|R P|327|L GLR1 GLutathione Reductase 483.0 0 0 0 0 0.3490154784198468 P41921 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.2581776976585388 0.2572547495365143 0.17961400747299194 0.12099810689687727 0.9029399752616882 0.35712000727653503 0.5089399814605713 0.9350000023841858 42.66796268377266 30.0 1.0 no 14889 chrXVI_376525 36404 no_effect YPL091W 1023 + ACACCTGTCGCTATTGCAGC P|343|A P|343|S T|342|R T|342|I GLR1 GLutathione Reductase 483.0 0 0 0 0 -1.1968840806010987 P41921 0.9562489986419678 0.9498909711837769 0.9476869702339172 0.9472420215606691 0.0 0.0 0.0 0.0 1.9003000259399412 2.396399974822998 -0.2275799959897995 -0.4022200107574463 2.601480007171631 3.2848300933837886 0.6798999905586243 0.0051600001752376565 55.757851812221524 55.00000000000001 1.0 no 14890 chrXVI_376552 36406 no_effect YPL091W 1050 + AAGCTGTCTAATAGACTGTT L|352|V silent|CTG>TTG|L|352 GLR1 GLutathione Reductase 483.0 0 0 0 0 0.7069740719861937 P41921 0.9512209892272948 0.0 2.2347400188446045 42.14013676029828 35.0 1.0 no 14891 chrXVI_387150r 36407 essential YPL085W 86 - ATTCAAGTGGTTCTTCACTG E|35|Q E|35|K SEC16 SECretory 2195.0 0 1 0 0 1.220851933396478 P48415 0.956179976463318 0.9475290179252625 0.1815074235200882 0.2361047863960266 45.72116377689309 40.0 1.0 no 14892 chrXVI_387163r 36408 essential YPL085W 99 - GTACTTTCTGGTAATTCAAG S|39|T S|39|N SEC16 SECretory 2195.0 0 1 0 0 -0.01772362049792156 P48415 0.9512869715690612 0.9536849856376648 0.1936831772327423 0.307254433631897 40.55237201664289 35.0 1.0 no 14893 chrXVI_387175r 36409 essential YPL085W 111 - CTGCTGTTAATCGTACTTTC S|43|T S|43|N SEC16 SECretory 2195.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.8139879025953791 P48415 0.9512869715690612 0.9536849856376648 0.6634802222251892 0.24376612901687625 45.18538906004079 40.0 1.0 no 14894 chrXVI_387192 36410 essential YPL085W 125 + CAGCAGCTTCAACGACGACT S|43|R silent|AGC>AGT|S|43 S|44|R silent|AGC>AGT|S|44 SEC16 SECretory 2195.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.5698019740293219 P48415 0.9417110085487366 0.9417110085487366 0.21435606479644773 0.39457091689109797 49.81373371945529 55.00000000000001 1.0 no 14895 chrXVI_387371r 36414 essential YPL085W 307 - TGGCAAATCATTTGAGTCCG L|108|F silent|TTG>TTA|L|108 SEC16 SECretory 2195.0 0 0 0 0 0.22770658290326384 P48415 0.9587849974632264 0.16797339916229248 46.115328905161505 45.0 1.0 no 14896 chrXVI_387428r 36415 essential YPL085W 364 - AGACATGGCTGGTTTTGTTT M|127|I M|127|I SEC16 SECretory 2195.0 0 0 0 0 1.321378765923511 P48415 0.9553959965705872 0.9553959965705872 0.22803404927253726 0.22803404927253726 49.136634646271325 40.0 1.0 no 14897 chrXVI_387493r 36419 essential YPL085W 429 - CCCGCGACTACATCGAGCGA silent|GCG>GCC|A|149 silent|GCG>GCA|A|149 G|150|R G|150|R SEC16 SECretory 2195.0 0 0 0 0 0.5171439859487534 P48415 0.941340982913971 0.941340982913971 0.6013545989990234 0.6013545989990234 55.503366614905254 65.0 1.0 no 14898 chrXVI_387655 36422 essential YPL085W 588 + AATCATTTTCTCCCATCCGA H|198|D H|198|Y SEC16 SECretory 2195.0 0 0 0 0 0.0069798912499099 P48415 0.9473130106925964 0.9489949941635132 0.856983482837677 0.15936985611915588 50.519576681685066 40.0 1.0 no 14899 chrXVI_387715 36423 essential YPL085W 648 + CCAACTCACAATGTTCCTCT P|217|R P|217|L T|218|S T|218|I SEC16 SECretory 2195.0 0 0 0 0 0.2451082740664889 P48415 0.9432820081710817 0.9430609941482544 0.9491789937019348 0.9472420215606691 0.634268045425415 0.3610272705554962 1.0 0.14995449781417847 49.75578122330194 45.0 1.0 no 14900 chrXVI_387730r 36425 essential YPL085W 666 - TCATTGTCTTTTGTGCCTAG E|229|Q E|229|K SEC16 SECretory 2195.0 0 0 0 0 -0.1643143767040877 P48415 0.956179976463318 0.9475290179252625 0.44897904992103577 0.6513275504112244 49.60600143182063 40.0 1.0 no 14901 chrXVI_387977r 36428 essential YPL085W 913 - GTCATCTTGAAACAACATGG D|311|H D|311|N D|310|H D|310|N SEC16 SECretory 2195.0 0 1 0 0 0.7971900642710569 P48415 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.09000197052955627 0.305680513381958 0.2812588214874268 0.5452415943145752 39.843085437794 40.0 1.0 no 14902 chrXVI_387980r 36429 essential YPL085W 916 - TTCGTCATCTTGAAACAACA E|312|Q E|312|K D|311|H D|311|N SEC16 SECretory 2195.0 0 1 0 0 0.7389784185807801 P48415 0.956179976463318 0.9475290179252625 0.9486550092697144 0.956179976463318 0.225599005818367 0.2513944208621979 0.09000197052955627 0.305680513381958 40.008601556328244 35.0 1.0 no 14903 chrXVI_387940r 36430 essential YPL085W 876 - TTTCTTATTTTATTCTCAGA R|298|T R|298|K SEC16 SECretory 2195.0 0 0 0 0 0.02535469047384875 P48415 0.932735025882721 0.955805003643036 0.7743432521820068 0.9658657908439636 38.624186549698265 20.0 1.0 no 14904 chrXVI_388018r 36431 essential YPL085W 954 - TTCTTCACATCTTCCTCCCA K|324|N silent|AAG>AAA|K|324 silent|GTG>GTC|V|323 silent|GTG>GTA|V|323 SEC16 SECretory 2195.0 0 0 0 0 0.23920437959290125 P48415 0.9355990290641784 0.2127542495727539 56.71858212576626 45.0 1.0 no 14905 chrXVI_388096 36432 essential YPL085W 1029 + GATCGTGATAAGGGTTATGA R|345|G R|345|C SEC16 SECretory 2195.0 0 1 0 0 0.16238139793330994 P48415 0.8994590044021606 0.8926740288734436 0.3642900884151459 0.04902177676558495 42.5849423783489 40.0 1.0 no 14906 chrXVI_388059 36433 essential YPL085W 992 + CACAAATAATACTCAAGAAT T|332|R T|332|I SEC16 SECretory 2195.0 0 0 0 0 -0.21025114403889306 P48415 0.9476869702339172 0.9472420215606691 0.5287057161331177 0.2815914452075958 31.01197617426232 25.0 1.0 no 14907 chrXVI_388183 36434 essential YPL085W 1116 + ACTTCAGAAGATATCTTTCA T|373|S T|373|I S|374|* S|374|L SEC16 SECretory 2195.0 1 Series([], Name: modification, dtype: object) 0 0 0 -1.5378867662505906 P48415 0.9491789937019348 0.9472420215606691 0.9298099875450134 0.2727687954902649 0.5222034454345703 0.0 39.913765665584826 30.0 1.0 no 14908 chrXVI_388485 36439 essential YPL085W 1418 + AAACGATGAGAAACTTCCTT N|474|K silent|AAC>AAT|N|474 SEC16 SECretory 2195.0 0 1 0 0 -0.1560379232393072 P48415 0.9439849853515624 0.0909685641527176 38.658477618007616 35.0 1.0 no 14909 chrXVI_388512 36442 essential YPL085W 1445 + TTCTGACGGTGAAGTATCAT S|483|C S|483|F D|484|E silent|GAC>GAT|D|484 SEC16 SECretory 2195.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.2445106152942721 P48415 0.945252001285553 0.9294660091400146 0.9532920122146606 0.10726965963840483 0.2174559235572815 1.0 44.089808529223774 40.0 1.0 no 14910 chrXVI_388614r 36443 essential YPL085W 1550 - AGCTGTCGTCGTCGTCCAAA S|523|T S|523|N D|522|H D|522|N SEC16 SECretory 2195.0 0 0 0 0 0.1929808884848884 P48415 0.9512869715690612 0.9536849856376648 0.9486550092697144 0.956179976463318 0.22282950580120087 0.2656812965869904 0.054003983736038215 0.19337034225463867 54.275661108101424 55.00000000000001 1.0 no 14911 chrXVI_388632 36445 essential YPL085W 1565 + CAGCTTTTTGGCTTCTTCTG S|523|R silent|AGC>AGT|S|523 SEC16 SECretory 2195.0 0 0 0 0 0.6054324460394865 P48415 0.9417110085487366 0.16744418442249298 51.61859367617915 45.0 1.0 no 14912 chrXVI_388669r 36446 essential YPL085W 1605 - TTCGTTGTATTATCGGTATT silent|ACG>ACC|T|541 silent|ACG>ACA|T|541 SEC16 SECretory 2195.0 0 0 0 0 -0.3079670029735033 P48415 42.954011489565524 30.0 1.0 no 14913 chrXVI_388777 36447 essential YPL085W 1710 + GTTCATTTTACCAATACTAC H|572|D H|572|Y SEC16 SECretory 2195.0 0 0 0 0 -0.25996334933658194 P48415 0.9473130106925964 0.9489949941635132 0.4354516267776489 0.2591717839241028 40.188356729164575 30.0 1.0 no 14914 chrXVI_388851r 36450 essential YPL085W 1787 - GTACACTGACTTGTTGGTTG V|602|L V|602|I S|601|T S|601|N SEC16 SECretory 2195.0 0 1 0 0 -0.1909519607314203 P48415 0.9539830088615416 0.9574310183525084 0.9512869715690612 0.9536849856376648 0.5458805561065674 0.5107167959213257 0.9607452154159546 0.3952812254428864 47.05629480759404 45.0 1.0 no 14915 chrXVI_388873r 36451 essential YPL085W 1809 - GGCTTAGGACTAACTATATT K|609|N silent|AAG>AAA|K|609 SEC16 SECretory 2195.0 0 1 0 0 -1.4560220620800692 P48415 0.9355990290641784 0.6243355870246887 42.038455315322494 35.0 1.0 no 14916 chrXVI_388888r 36452 essential YPL085W 1824 - TCTTTTACCACAGGAGGCTT D|615|H D|615|N SEC16 SECretory 2195.0 0 0 0 0 -0.5730329288232971 P48415 0.9486550092697144 0.956179976463318 0.1132984310388565 0.38716763257980347 51.74486508491385 45.0 1.0 no 14917 chrXVI_388917 36454 essential YPL085W 1850 + TTCAAATTTTAAGATAAATG S|618|* S|618|L SEC16 SECretory 2195.0 0 0 0 0 0.3324094363770884 P48415 0.9298099875450134 0.18170477449893951 26.865376346698557 15.0 1.0 no 14918 chrXVI_388994r 36455 essential YPL085W 1930 - CGGCTTTGCGTGACCCTTCT K|649|N silent|AAG>AAA|K|649 SEC16 SECretory 2195.0 0 0 0 0 0.4146670346382066 P48415 0.9355990290641784 0.0 59.68208157898846 60.0 1.0 no 14919 chrXVI_389020 36457 essential YPL085W 1953 + GCCGTTCCTACTCAAAGGTT silent|GCC>GCG|A|652 silent|GCC>GCT|A|652 A|652|G A|652|V SEC16 SECretory 2195.0 0 0 0 0 0.5838798832581955 P48415 0.9484469890594482 0.9504740238189696 1.0 0.03007103130221367 53.38945073460918 50.0 1.0 no 14920 chrXVI_389026r 36458 essential YPL085W 1962 - CCTGAGCCAAACCTTTGAGT G|661|R G|661|R G|659|A G|659|D SEC16 SECretory 2195.0 0 1 0 0 0.29557683053855593 P48415 0.941340982913971 0.941340982913971 0.9499930143356324 0.9446240067481996 0.2562080919742584 0.2562080919742584 0.5230811834335327 0.5997194647789001 51.92630431005245 50.0 1.0 no 14921 chrXVI_389277 36464 essential YPL085W 2210 + ACCTCCCCCAGCATTAAAAG P|738|R P|738|L P|738|A P|738|S SEC16 SECretory 2195.0 0 0 0 0 -0.7663311580153828 P48415 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.17757488787174225 0.09885013848543167 0.7643555998802185 0.2371760457754135 52.29423646685791 50.0 1.0 no 14922 chrXVI_389278r 36465 essential YPL085W 2214 - TCCACTTTTAATGCTGGGGG silent|GTG>GTC|V|744 silent|GTG>GTA|V|744 E|745|Q E|745|K SEC16 SECretory 2195.0 0 0 0 0 -1.9679069692700764 P48415 0.956179976463318 0.9475290179252625 0.4560172259807586 0.582629919052124 51.30790932707134 50.0 1.0 no 14923 chrXVI_389306 36466 essential YPL085W 2239 + CCGTTTCTGCTCCTCCAATT silent|ACC>ACG|T|747 silent|ACC>ACT|T|747 S|749|C S|749|F SEC16 SECretory 2195.0 0 0 0 0 -0.013664680435576216 P48415 0.945252001285553 0.9294660091400146 0.07085144519805907 0.10001213103532793 56.74986761191428 50.0 1.0 no 14924 chrXVI_389390 36470 essential YPL085W 2323 + CACAGTACGGCCTCAATAAC Q|776|E Q|776|* SEC16 SECretory 2195.0 0 0 0 0 -2.486526475301842 P48415 0.9590039849281312 0.8869072794914246 46.721879297865655 50.0 1.0 yes 14925 chrXVI_389377 36471 essential YPL085W 2310 + GCTAGACATGCAACACAGTA A|771|G A|771|V H|773|D H|773|Y SEC16 SECretory 2195.0 0 1 0 0 -0.2341005564368569 P48415 0.9484469890594482 0.9504740238189696 0.9473130106925964 0.9489949941635132 0.3876594305038452 0.3715882897377014 0.5565256476402283 0.9732947349548341 46.17311177792493 45.0 1.0 no 14926 chrXVI_389391 36472 essential YPL085W 2324 + ACAGTACGGCCTCAATAACG Q|776|E Q|776|* Y|777|* silent|TAC>TAT|Y|777 SEC16 SECretory 2195.0 0 0 0 0 -0.7119362766303202 P48415 0.9590039849281312 0.8869072794914246 46.57644450156431 50.0 1.0 no 14927 chrXVI_389413 36475 essential YPL085W 2346 + GTACCTCCGGTTTCGCCATA P|784|A P|784|S P|784|R P|784|L SEC16 SECretory 2195.0 0 1 0 0 0.6398542130066398 P48415 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 1.0 0.3953792452812195 0.16357387602329254 0.4973762631416321 58.67211833685565 55.00000000000001 1.0 no 14928 chrXVI_389444r 36477 essential YPL085W 2380 - ATTCGCAGTTGGCAAATTTA silent|GCG>GCC|A|799 silent|GCG>GCA|A|799 A|799|P A|799|T SEC16 SECretory 2195.0 0 0 0 0 -0.4092829528870988 P48415 0.9573720097541808 0.9523990154266356 0.2756693661212921 0.5670041441917419 43.80892047280354 35.0 1.0 no 14929 chrXVI_389509r 36481 essential YPL085W 2445 - CCAAGGTTTTGCACAACTGA G|822|R G|822|S SEC16 SECretory 2195.0 0 1 0 0 1.53838327995594 P48415 0.941340982913971 0.951104998588562 0.09105195105075836 0.2145259231328964 47.17882080057228 45.0 1.0 no 14930 chrXVI_389540r 36483 essential YPL085W 2476 - TACAAAATTGGGGGTATTTA V|832|L V|832|I SEC16 SECretory 2195.0 0 1 0 0 -0.4396880591609175 P48415 0.9539830088615416 0.9574310183525084 0.4631862044334412 0.4942783415317536 37.97918265405622 30.0 1.0 no 14931 chrXVI_389665 36486 essential YPL085W 2598 + CCATATACCTCACAACCTGT P|867|R P|867|L SEC16 SECretory 2195.0 0 0 0 0 0.3122923062172257 P48415 0.9432820081710817 0.9430609941482544 50.23398161522329 45.0 1.0 no 14932 chrXVI_389677 36489 essential YPL085W 2610 + CAACCTGTTGGTCCTGTAGC P|872|A P|872|S P|872|R P|872|L SEC16 SECretory 2195.0 0 0 0 0 0.7172602026669643 P48415 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.77268385887146 0.3486614227294922 0.1475057452917099 0.457074373960495 55.505419396620475 55.00000000000001 1.0 no 14933 chrXVI_389689r 36490 essential YPL085W 2625 - TAGCTTGAATTCCCAGCTAC S|881|T S|881|N SEC16 SECretory 2195.0 0 0 0 0 1.030565944194196 P48415 0.9512869715690612 0.9536849856376648 49.821071732709534 45.0 1.0 no 14934 chrXVI_389718r 36491 essential YPL085W 2654 - CTGCATAAGAACTTCGGGTT A|891|P A|891|T SEC16 SECretory 2195.0 0 0 0 0 1.0333610372316424 P48415 0.9573720097541808 0.9523990154266356 0.242219552397728 0.4715913236141205 45.94360471326559 45.0 1.0 no 14935 chrXVI_389753r 36493 essential YPL085W 2689 - ACTTGCTGAAGTTTGAGCCT S|903|T S|903|N A|902|P A|902|T SEC16 SECretory 2195.0 0 0 0 0 0.13664231182842734 P48415 0.9512869715690612 0.9536849856376648 0.9573720097541808 0.9523990154266356 0.5627654194831848 0.4786231815814972 0.2901627123355865 0.6313871145248413 50.72545493591406 45.0 1.0 no 14936 chrXVI_389923r 36501 essential YPL085W 2859 - GGCAGTATGTTTTCAGCAAG silent|CTG>CTC|L|959 silent|CTG>CTA|L|959 SEC16 SECretory 2195.0 0 0 0 0 0.16717849846258864 P48415 47.997870986767616 45.0 1.0 no 14937 chrXVI_390038 36504 essential YPL085W 2971 + GTCAATTTCCGATTTTTCAT Q|992|E Q|992|* SEC16 SECretory 2195.0 0 0 0 0 1.565425115995914 P48415 0.9590039849281312 0.0 -0.27121999859809875 2.2090001106262207 43.6439876836244 30.0 1.0 no 14938 chrXVI_390054 36505 essential YPL085W 2987 + TCATTGGAGTGCTGCAAACA H|997|D H|997|Y SEC16 SECretory 2195.0 0 0 0 0 -1.023249409902483 P48415 0.9473130106925964 0.9489949941635132 0.6328529715538025 0.3443388044834137 0.13189999759197235 -0.3171800076961517 0.4519200026988983 -0.5924999713897705 2.591360092163086 -0.6711000204086304 47.080555753722756 45.0 1.0 no 14939 chrXVI_389874r 36506 essential YPL085W 2810 - CAGCCGTTATGTTGCTTGCA A|943|P A|943|T silent|ACG>ACC|T|942 silent|ACG>ACA|T|942 SEC16 SECretory 2195.0 0 0 0 0 0.2925385251709802 P48415 0.9573720097541808 0.9523990154266356 0.27556923031806946 0.5241582989692688 55.052107413212575 50.0 1.0 no 14940 chrXVI_390178r 36510 essential YPL085W 3114 - AAGCTTTTGAGCATATCGTT S|1044|T S|1044|N SEC16 SECretory 2195.0 0 0 0 0 -1.034062104630042 P48415 0.9512869715690612 0.9536849856376648 0.2879916131496429 0.03121180459856987 -0.3101600110530853 -0.15892000496387482 44.68575056152657 35.0 1.0 no 14941 chrXVI_390201r 36511 essential YPL085W 3137 - TGGCACTACCCAAAGGACCT A|1052|P A|1052|T S|1051|T S|1051|N SEC16 SECretory 2195.0 0 0 0 0 -0.4813480948716311 P48415 0.9573720097541808 0.9523990154266356 0.9512869715690612 0.9536849856376648 0.12541215121746066 0.35596421360969543 0.2961447238922119 0.3682870864868164 -0.6712999939918518 0.1907999962568283 -0.2280399948358536 -1.303699970245361 -1.063040018081665 0.4915800094604492 53.67651287742297 55.00000000000001 1.0 no 14942 chrXVI_390290 36513 essential YPL085W 3223 + CATCCACTGATATGACTATA S|1076|C S|1076|F silent|TCC>TCG|S|1076 silent|TCC>TCT|S|1076 SEC16 SECretory 2195.0 0 0 0 0 0.5593408426710281 P48415 0.945252001285553 0.9294660091400146 0.05222339555621147 0.07886026054620743 0.04442000016570091 -0.05827999860048294 0.062259998172521584 -0.2537800073623657 41.98459047139721 35.0 1.0 no 14943 chrXVI_390293r 36514 essential YPL085W 3229 - TTGCCATATAGTCATATCAG W|1082|C W|1082|* W|1082|S W|1082|* SEC16 SECretory 2195.0 0 0 0 0 -0.9967923939847484 P48415 0.8858469724655151 0.8858469724655151 0.012179509736597538 0.022068079560995102 4.80024003982544 6.0638999938964835 43.824996611260595 35.0 1.0 no 14944 chrXVI_390409r 36516 essential YPL085W 3345 - ATCATGTCACCGTTTGGAAA M|1121|I M|1121|I SEC16 SECretory 2195.0 0 0 0 0 0.5360164828747219 P48415 0.9553959965705872 0.9553959965705872 0.4853570759296417 0.4853570759296417 0.11016000062227248 0.11016000062227248 0.1179800033569336 0.1179800033569336 0.4823900163173676 0.4823900163173676 45.41300626800063 40.0 1.0 no 14945 chrXVI_390513 36519 essential YPL085W 3446 + TCGCTTAGCTTTAAGCAAGA silent|CGC>CGG|R|1150 silent|CGC>CGT|R|1150 R|1150|G R|1150|C SEC16 SECretory 2195.0 0 0 0 0 1.413617167252187 P48415 0.8994590044021606 0.8926740288734436 0.15596875548362732 0.022663107141852382 0.5808600187301636 0.6299399733543396 45.36419578170802 40.0 1.0 no 14946 chrXVI_390542r 36520 essential YPL085W 3478 - ACTGCCAACCAATAGTGCAA S|1166|T S|1166|N G|1165|A G|1165|D SEC16 SECretory 2195.0 0 0 0 0 0.9013574214823218 P48415 0.9512869715690612 0.9536849856376648 0.9499930143356324 0.9446240067481996 0.16091494262218475 0.17392349243164062 0.15292741358280182 0.057967152446508415 0.2846600115299225 0.8616200089454651 -0.9766799807548524 7.944139957427978 1.1344380378723145 0.8228440284729004 48.02972656537422 45.0 1.0 no 14947 chrXVI_390549 36521 essential YPL085W 3482 + ACTATTGGTTGGCAGTTTAA L|1162|V silent|CTA>TTA|L|1162 SEC16 SECretory 2195.0 0 1 0 0 0.5186242307756939 P48415 0.9512209892272948 0.0 3.098639965057373 1.119760036468506 4.314189910888672 44.76840516973857 35.0 1.0 no 14948 chrXVI_390666r 36523 essential YPL085W 3602 - CAACAAATACTTGAAAGATA V|1207|L V|1207|I SEC16 SECretory 2195.0 0 0 0 0 0.12561403645749053 P48415 0.9539830088615416 0.9574310183525084 0.0949435755610466 0.6130273342132568 -0.907639980316162 0.012959999963641168 -1.4986399412155151 -0.5214599967002869 -1.176900029182434 -0.17775000631809235 30.40030215103457 25.0 1.0 no 14949 chrXVI_390749r 36524 essential YPL085W 3685 - AACGATACTCTTCCAGTTTT V|1235|L V|1235|I SEC16 SECretory 2195.0 0 0 0 0 0.3386135260104685 P48415 0.9539830088615416 0.9574310183525084 0.07239028066396712 0.12064886838197708 -0.16888000071048734 -0.032359998673200614 44.86899135572117 35.0 1.0 no 14950 chrXVI_390924 36527 essential YPL085W 3857 + ACTTTCTAATGAGCCAGTAA L|1287|V L|1287|F S|1288|C S|1288|F SEC16 SECretory 2195.0 0 0 0 0 -0.9735659795362904 P48415 0.9512209892272948 0.9587849974632264 0.945252001285553 0.9294660091400146 0.0725250393152237 0.2786594033241272 0.0 0.0 1.7274199724197388 5.816460132598878 -0.025059999898076057 -0.015860000625252724 1.7846399545669556 4.492859840393066 43.32022870463192 35.0 1.0 no 14951 chrXVI_390955 36529 essential YPL085W 3888 + GACGTTATATTTGAAAGTAT D|1297|E silent|GAC>GAT|D|1297 SEC16 SECretory 2195.0 0 0 0 0 0.19530781499361946 P48415 0.9532920122146606 0.3057794272899628 -0.3390600085258484 34.81759155797323 25.0 1.0 no 14952 chrXVI_390986 36530 essential YPL085W 3919 + ATACTTTTGAAAGCATTCTA T|1308|S T|1308|I SEC16 SECretory 2195.0 0 0 0 0 0.4344815080457997 P48415 0.9491789937019348 0.9472420215606691 0.791656494140625 0.03239307180047035 -0.5240399837493896 2.9437201023101807 0.7518399953842163 3.060400009155273 37.45470907604454 25.0 1.0 no 14953 chrXVI_390987 36531 essential YPL085W 3920 + TACTTTTGAAAGCATTCTAT T|1308|S T|1308|I SEC16 SECretory 2195.0 0 0 0 0 -0.056861470053354825 P48415 0.9491789937019348 0.9472420215606691 0.791656494140625 0.03239307180047035 -0.5240399837493896 2.9437201023101807 0.7518399953842163 3.060400009155273 37.454709076044594 25.0 1.0 no 14954 chrXVI_391197r 36534 essential YPL085W 4133 - CCTCACTCAATTCACGAGTG E|1384|Q E|1384|K E|1384|D silent|GAG>GAA|E|1384 SEC16 SECretory 2195.0 0 0 0 0 0.2819959860845612 P48415 0.956179976463318 0.9475290179252625 0.94931298494339 0.5475384593009949 0.8250968456268309 0.609549343585968 -0.2053000032901764 0.06081999838352204 0.057039998471736915 -0.08083999902009964 0.4609600007534027 0.05183999985456467 48.17248230010325 50.0 1.0 no 14955 chrXVI_391197 36535 essential YPL085W 4130 + CCTCACTCGTGAATTGAGTG silent|CTC>CTG|L|1378 silent|CTC>CTT|L|1378 L|1378|V L|1378|F SEC16 SECretory 2195.0 0 0 0 0 0.039408038720217996 P48415 0.9512209892272948 0.9587849974632264 0.08341505378484726 0.04265539720654488 2.862060070037842 3.5083398818969727 1.272480010986328 3.3805201053619385 47.87312856374933 50.0 1.0 no 14956 chrXVI_391228 36537 essential YPL085W 4161 + AGGCTTTCCGAGTCTAATAC L|1389|V L|1389|F SEC16 SECretory 2195.0 0 0 0 0 -0.3179942738872414 P48415 0.9512209892272948 0.9587849974632264 0.7865548133850098 0.06496615707874298 3.5053200721740723 5.587200164794922 2.8472199440002437 1.2710200548171997 48.20429224260249 45.0 1.0 no 14957 chrXVI_391232 36538 essential YPL085W 4165 + TTTCCGAGTCTAATACAGGA S|1390|C S|1390|F silent|TCC>TCG|S|1390 silent|TCC>TCT|S|1390 SEC16 SECretory 2195.0 0 0 0 0 -0.10379044581428616 P48415 0.945252001285553 0.9294660091400146 0.030228970572352413 0.014877771958708763 0.09201999753713608 0.6042799949645996 45.1976928741741 40.0 1.0 no 14958 chrXVI_391496r 36544 essential YPL085W 4432 - ACTATGGCTTGGTACATTAT S|1484|T S|1484|N SEC16 SECretory 2195.0 0 0 0 0 -0.11499031592753133 P48415 0.9512869715690612 0.9536849856376648 0.5742649435997009 0.1701255440711975 44.8904219151251 35.0 1.0 no 14959 chrXVI_391497r 36545 essential YPL085W 4433 - CACTATGGCTTGGTACATTA S|1484|T S|1484|N SEC16 SECretory 2195.0 0 0 0 0 1.1967854237607802 P48415 0.9512869715690612 0.9536849856376648 0.5742649435997009 0.1701255440711975 46.23557844019518 40.0 1.0 no 14960 chrXVI_391512r 36546 essential YPL085W 4448 - GCTTTGAATGCAGCACACTA K|1489|N silent|AAG>AAA|K|1489 SEC16 SECretory 2195.0 0 0 0 0 0.2865006849498827 P48415 0.9355990290641784 0.4245768487453461 48.345684099146006 45.0 1.0 no 14961 chrXVI_391531 36547 essential YPL085W 4464 + AAGCCTTCCAATGTGTCAAA P|1490|A P|1490|S P|1490|R P|1490|L SEC16 SECretory 2195.0 0 0 0 0 -0.00962988944275045 P48415 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.5967691540718079 0.4789087772369385 0.40154287219047546 1.0 46.15461734922097 40.0 1.0 no 14962 chrXVI_391538r 36548 essential YPL085W 4474 - AACTAACCCCTTTGACACAT V|1498|L V|1498|I silent|GGG>GGC|G|1496 silent|GGG>GGA|G|1496 SEC16 SECretory 2195.0 0 0 0 0 0.4809098695893661 P48415 0.9539830088615416 0.9574310183525084 0.1607336401939392 0.24263939261436465 46.718669310474574 40.0 1.0 no 14963 chrXVI_391570 36549 essential YPL085W 4503 + TTACCGTATACGCATAGGAT P|1503|A P|1503|S P|1503|R P|1503|L SEC16 SECretory 2195.0 0 0 0 0 1.1427534731915403 P48415 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 1.0 0.5277781486511229 0.2545183300971985 0.6747082471847534 45.55907413907885 40.0 1.0 no 14964 chrXVI_391573r 36550 essential YPL085W 4509 - TCACCGATCCTATGCGTATA G|1509|A G|1509|D D|1510|H D|1510|N SEC16 SECretory 2195.0 0 1 0 0 0.2081671184955048 P48415 0.9499930143356324 0.9446240067481996 0.9486550092697144 0.956179976463318 0.2602739334106445 0.7767010331153871 0.08085916936397552 0.7143677473068237 50.28933732152746 45.0 1.0 no 14965 chrXVI_391651r 36552 essential YPL085W 4587 - CTTCTCAAAGAAGCCATTTG R|1535|T R|1535|K L|1534|F silent|TTG>TTA|L|1534 SEC16 SECretory 2195.0 0 0 0 0 0.09846745977401596 P48415 0.932735025882721 0.955805003643036 0.9587849974632264 0.22297610342502594 0.7517085671424866 0.6743636131286621 42.56690666698773 40.0 1.0 no 14966 chrXVI_391686r 36553 essential YPL085W 4622 - AAGCCTTTTCGTTTGTATGC A|1547|P A|1547|T K|1546|N silent|AAG>AAA|K|1546 SEC16 SECretory 2195.0 0 1 0 0 0.21816327131723606 P48415 0.9573720097541808 0.9523990154266356 0.9355990290641784 0.2478998601436615 0.6217461824417114 0.4315051734447479 48.79627052347075 40.0 1.0 no 14967 chrXVI_391741 36554 essential YPL085W 4674 + ACGGCCTACACTCCACAATT T|1559|R T|1559|M A|1560|G A|1560|V SEC16 SECretory 2195.0 0 1 0 0 -0.15589554563161154 P48415 0.9476869702339172 0.9502379894256592 0.9484469890594482 0.9504740238189696 0.5138086676597595 0.1118130460381508 0.4721703231334686 0.29406699538230896 52.115566966969034 50.0 1.0 no 14968 chrXVI_391764 36555 essential YPL085W 4697 + ACAGAACCATAGCGTTCCAA Q|1567|E Q|1567|* N|1568|K silent|AAC>AAT|N|1568 SEC16 SECretory 2195.0 0 0 0 0 -0.7046080501312573 P48415 0.9590039849281312 0.9439849853515624 1.0 0.1693768948316574 47.877776241946314 45.0 1.0 no 14969 chrXVI_391770r 36556 essential YPL085W 4706 - ACTTTTCCATTGGAACGCTA K|1575|N silent|AAG>AAA|K|1575 E|1574|Q E|1574|K SEC16 SECretory 2195.0 0 1 0 0 -0.1752302866987819 P48415 0.9355990290641784 0.956179976463318 0.9475290179252625 0.1517515629529953 0.494218647480011 0.9359107613563538 47.22277933095416 40.0 1.0 no 14970 chrXVI_391780r 36557 essential YPL085W 4716 - TTCGAATTAGACTTTTCCAT silent|TCG>TCC|S|1578 silent|TCG>TCA|S|1578 SEC16 SECretory 2195.0 0 0 0 0 0.4197070995069141 P48415 41.630132131552784 30.0 1.0 no 14971 chrXVI_391837r 36560 essential YPL085W 4773 - GACGGCACTGTTCCAAGTTT silent|CCG>CCC|P|1597 silent|CCG>CCA|P|1597 silent|GTG>GTC|V|1596 silent|GTG>GTA|V|1596 SEC16 SECretory 2195.0 0 0 0 0 -0.4753025741639762 P48415 52.18349296814705 50.0 1.0 no 14972 chrXVI_391838r 36561 essential YPL085W 4774 - AGACGGCACTGTTCCAAGTT silent|CCG>CCC|P|1597 silent|CCG>CCA|P|1597 silent|GTG>GTC|V|1596 silent|GTG>GTA|V|1596 SEC16 SECretory 2195.0 0 0 0 0 -1.8561707506979488 P48415 52.01842823709438 50.0 1.0 no 14973 chrXVI_391876r 36563 essential YPL085W 4812 - GACTCCCTTCTTACTAAGTC E|1610|D silent|GAG>GAA|E|1610 E|1610|Q E|1610|K SEC16 SECretory 2195.0 0 1 0 0 0.4978029192677348 P48415 0.94931298494339 0.956179976463318 0.9475290179252625 0.636454701423645 0.6690341830253601 0.9627223610877992 49.98738035710164 45.0 1.0 no 14974 chrXVI_391922 36564 essential YPL085W 4855 + TTCTTCCTCCTCCCAAAATT L|1620|V L|1620|F P|1621|A P|1621|S SEC16 SECretory 2195.0 0 1 0 0 0.4222447533220587 P48415 0.9512209892272948 0.9587849974632264 0.9562489986419678 0.9498909711837769 0.17655427753925326 0.1183219850063324 0.6718359589576721 0.3441680371761322 51.111497033487865 40.0 1.0 no 14975 chrXVI_391923 36565 essential YPL085W 4856 + TCTTCCTCCTCCCAAAATTG L|1620|V L|1620|F P|1621|A P|1621|S SEC16 SECretory 2195.0 0 1 0 0 1.0200692081309266 P48415 0.9512209892272948 0.9587849974632264 0.9562489986419678 0.9498909711837769 0.17655427753925326 0.1183219850063324 0.6718359589576721 0.3441680371761322 50.814165720252895 45.0 1.0 no 14976 chrXVI_391950 36566 essential YPL085W 4883 + TACTAAAGCTAATTCCTCGC T|1629|S T|1629|I SEC16 SECretory 2195.0 0 0 0 0 0.05831565518941768 P48415 0.9491789937019348 0.9472420215606691 0.5549159049987793 0.15469278395175934 43.625524144670685 40.0 1.0 no 14977 chrXVI_391948r 36567 essential YPL085W 4884 - TGCGAGGAATTAGCTTTAGT silent|TCG>TCC|S|1634 silent|TCG>TCA|S|1634 SEC16 SECretory 2195.0 0 0 0 0 -0.8164954520446047 P48415 45.254030475169145 40.0 1.0 no 14978 chrXVI_391951 36568 essential YPL085W 4884 + ACTAAAGCTAATTCCTCGCA T|1629|S T|1629|I SEC16 SECretory 2195.0 0 0 0 0 -0.01975703966199049 P48415 0.9491789937019348 0.9472420215606691 0.5549159049987793 0.15469278395175934 45.380791432006454 40.0 1.0 no 14979 chrXVI_397068 36571 essential YPL083C 1018 - TTCGAATTTATAATCAAGTG E|346|Q E|346|K SEN54 Splicing ENdonuclease 467.0 0 0 0 0 -0.4611121836062353 Q02825 0.956179976463318 0.9475290179252625 0.06747502088546753 0.05992526933550835 33.265944414369244 25.0 0.0 no 14980 chrXVI_397185 36574 essential YPL083C 901 - TCTTTTCTTGAAATTAGAAT R|307|T R|307|K K|305|N silent|AAG>AAA|K|305 SEN54 Splicing ENdonuclease 467.0 0 0 0 0 0.8638047603778538 Q02825 0.932735025882721 0.955805003643036 0.9355990290641784 0.02318726852536201 1.0 0.010287754237651823 33.64560013766385 20.0 0.0 no 14981 chrXVI_397209 36575 essential YPL083C 877 - TTTCCATACTTTAAATGTCA W|298|C W|298|* W|298|S W|298|* SEN54 Splicing ENdonuclease 467.0 0 0 0 0 -0.4703155015589512 Q02825 0.8858469724655151 0.8858469724655151 0.0 0.0 39.39572944509757 25.0 0.0 no 14982 chrXVI_397313 36577 essential YPL083C 773 - GAACAAGCCTATTTAAACCC V|264|L V|264|I SEN54 Splicing ENdonuclease 467.0 0 0 0 0 0.5179617148510879 Q02825 0.9539830088615416 0.9574310183525084 0.0483943447470665 1.0 43.198956181261785 40.0 0.0 no 14983 chrXVI_397330r 36578 essential YPL083C 753 + ACTTCACCACAGTTATACCA T|252|S T|252|I S|253|* S|253|L SEN54 Splicing ENdonuclease 467.0 0 0 0 0 -0.2921064796248545 Q02825 0.9491789937019348 0.9472420215606691 0.9298099875450134 0.9634045362472534 0.020777132362127304 0.01800067350268364 48.76080491553574 40.0 0.0 no 14984 chrXVI_397331r 36579 essential YPL083C 752 + GACTTCACCACAGTTATACC T|252|S T|252|I S|253|* S|253|L SEN54 Splicing ENdonuclease 467.0 0 0 0 0 -0.14395005844283562 Q02825 0.9491789937019348 0.9472420215606691 0.9298099875450134 0.9634045362472534 0.020777132362127304 0.01800067350268364 48.702106071887606 45.0 0.0 no 14985 chrXVI_397470 36580 essential YPL083C 616 - TTGCTTTTTCAATGGGAAAA K|211|N silent|AAG>AAA|K|211 SEN54 Splicing ENdonuclease 467.0 0 0 0 0 0.2215027164770864 Q02825 0.9355990290641784 0.4990569651126862 38.61203157248133 30.0 0.0 no 14986 chrXVI_397500 36581 essential YPL083C 586 - GACTGCTGCTTCTTGATTGC V|202|L V|202|I A|201|P A|201|T SEN54 Splicing ENdonuclease 467.0 0 0 0 0 0.2426995176281924 Q02825 0.9539830088615416 0.9574310183525084 0.9573720097541808 0.9523990154266356 0.287070631980896 0.17768633365631106 0.2901760935783386 0.5027808547019958 52.49106485764236 50.0 0.0 no 14987 chrXVI_397501 36582 essential YPL083C 585 - ACTGCTGCTTCTTGATTGCT V|202|L V|202|I A|201|P A|201|T SEN54 Splicing ENdonuclease 467.0 0 0 0 0 0.3429369161118088 Q02825 0.9539830088615416 0.9574310183525084 0.9573720097541808 0.9523990154266356 0.287070631980896 0.17768633365631106 0.2901760935783386 0.5027808547019958 53.12330315314188 45.0 0.0 no 14988 chrXVI_397580r 36583 essential YPL083C 503 + TTCGCTGTTTTCATCGCAAC S|169|W S|169|L L|170|V silent|CTG>TTG|L|170 SEN54 Splicing ENdonuclease 467.0 0 0 0 0 0.8578601515395147 Q02825 0.9288619756698608 0.9298099875450134 0.9512209892272948 0.05413082614541054 0.54585200548172 0.03447351232171059 48.79267065798182 45.0 0.0 no 14989 chrXVI_397613r 36584 essential YPL083C 470 + AACAGAGATTTTACTCAGTA T|158|R T|158|I SEN54 Splicing ENdonuclease 467.0 0 0 0 0 1.0510877975524258 Q02825 0.9476869702339172 0.9472420215606691 0.592982292175293 0.5222591161727905 38.5779436720664 30.0 0.0 no 14990 chrXVI_397660 36585 essential YPL083C 426 - CCTGCTTCTAATCTATAATA G|149|R G|149|S A|148|P A|148|T SEN54 Splicing ENdonuclease 467.0 0 0 0 0 0.6483018654255519 Q02825 0.941340982913971 0.951104998588562 0.9573720097541808 0.9523990154266356 0.5446668267250061 0.9173598289489746 0.23526813089847565 0.4382299184799193 41.00559559551186 30.0 0.0 no 14991 chrXVI_397700 36587 essential YPL083C 386 - CTGCCAAATAAACAAACTCA A|135|P A|135|T L|134|F silent|TTG>TTA|L|134 SEN54 Splicing ENdonuclease 467.0 0 0 0 0 0.1533782048417122 Q02825 0.9573720097541808 0.9523990154266356 0.9587849974632264 0.037340130656957626 0.04860788583755493 0.0 37.60114291735772 35.0 0.0 no 14992 chrXVI_397760r 36590 essential YPL083C 323 + AGGCAGCTTTATGCAAACGA silent|GGC>GGG|G|109 silent|GGC>GGT|G|109 S|110|R silent|AGC>AGT|S|110 SEN54 Splicing ENdonuclease 467.0 0 0 0 0 0.2238204028217905 Q02825 0.9417110085487366 0.03263184055685997 46.82485436197061 45.0 0.0 no 14993 chrXVI_397780r 36592 essential YPL083C 303 + GCCGTTCTACTTAAACCCAA silent|GCC>GCG|A|102 silent|GCC>GCT|A|102 A|102|G A|102|V SEN54 Splicing ENdonuclease 467.0 0 0 0 0 -0.5955939905167873 Q02825 0.9484469890594482 0.9504740238189696 0.0 0.0 49.31944432394732 45.0 0.0 no 14994 chrXVI_397915 36596 essential YPL083C 171 - TCTTGCAAATTAGTCCCATC D|64|H D|64|N L|62|F silent|TTG>TTA|L|62 SEN54 Splicing ENdonuclease 467.0 0 0 0 0 0.17968495713628446 Q02825 0.9486550092697144 0.956179976463318 0.9587849974632264 0.013835565187036993 0.027431724593043327 0.11883052438497545 47.46074721334753 40.0 0.0 no 14995 chrXVI_397954r 36597 essential YPL083C 129 + GCTCTTTCACTTCCAAAGAG L|45|V L|45|F A|44|G A|44|V SEN54 Splicing ENdonuclease 467.0 0 0 0 0 0.6049181654599929 Q02825 0.9512209892272948 0.9587849974632264 0.9484469890594482 0.9504740238189696 0.5141236186027527 0.6984972357749939 0.3980904519557953 0.32484227418899536 47.31882156248696 45.0 0.0 no 14996 chrXVI_397956r 36598 essential YPL083C 127 + CTGCTCTTTCACTTCCAAAG A|44|G A|44|V L|45|V L|45|F SEN54 Splicing ENdonuclease 467.0 0 0 0 0 0.8147369761983175 Q02825 0.9484469890594482 0.9504740238189696 0.9512209892272948 0.9587849974632264 0.3980904519557953 0.32484227418899536 0.5141236186027527 0.6984972357749939 47.82496487314523 45.0 0.0 no 14997 chrXVI_398057r 36600 essential YPL083C 26 + TCAAGTGACCACATCTAATC Q|10|E Q|10|* SEN54 Splicing ENdonuclease 467.0 0 0 0 0 1.3264277628023922 Q02825 0.9590039849281312 42.86357642770514 40.0 0.0 no 14998 chrXVI_399963 36601 essential YPL082C 4101 - CTCAGAGTTAATCTGACAGT silent|CTG>CTC|L|1373 silent|CTG>CTA|L|1373 MOT1 Modifier of Transcription 1867.0 0 0 0 0 1.3515870809413384 P32333 43.66813149525609 40.0 0.0 no 14999 chrXVI_399964 36602 essential YPL082C 4100 - TCAGAGTTAATCTGACAGTT silent|CTG>CTC|L|1373 silent|CTG>CTA|L|1373 MOT1 Modifier of Transcription 1867.0 0 0 0 0 0.7300859196807009 P32333 41.99071363991175 35.0 0.0 no 15000 chrXVI_399995 36603 essential YPL082C 4069 - ATACACAACAACCTTTAAAA silent|GTG>GTC|V|1362 silent|GTG>GTA|V|1362 V|1362|L V|1362|M MOT1 Modifier of Transcription 1867.0 0 0 0 0 0.07973050659827602 P32333 0.9473379850387572 0.8971480131149292 0.488798975944519 0.13599488139152527 33.98673473580794 25.0 0.0 no 15001 chrXVI_399996 36605 essential YPL082C 4068 - TACACAACAACCTTTAAAAA silent|GTG>GTC|V|1362 silent|GTG>GTA|V|1362 V|1362|L V|1362|M MOT1 Modifier of Transcription 1867.0 0 0 0 0 0.541427397749378 P32333 0.9473379850387572 0.8971480131149292 0.488798975944519 0.13599488139152527 32.91532309568106 25.0 0.0 no 15002 chrXVI_400130r 36609 essential YPL082C 3931 + TCGCAAGCGATCAATATTTG A|1312|G A|1312|V I|1311|M silent|ATC>ATT|I|1311 MOT1 Modifier of Transcription 1867.0 0 0 0 0 -0.5936072857470557 P32333 0.86149001121521 0.8644850254058838 0.8993560075759888 0.13263097405433655 0.011061811819672585 0.10043440759181976 41.99009651577558 40.0 0.0 no 15003 chrXVI_400356 36614 essential YPL082C 3708 - CTGCTTGCCACTAGTTCTTC S|1242|T S|1242|N MOT1 Modifier of Transcription 1867.0 0 0 0 0 0.00932909025912342 P32333 0.976472020149231 0.9840989708900452 0.02453049458563328 0.3003988862037659 54.94522274463424 50.0 0.0 no 15004 chrXVI_400357 36615 essential YPL082C 3707 - TGCTTGCCACTAGTTCTTCT S|1242|T S|1242|N A|1241|P A|1241|T MOT1 Modifier of Transcription 1867.0 0 0 0 0 0.12646012180973148 P32333 0.976472020149231 0.9840989708900452 0.8679670095443726 0.9534239768981934 0.02453049458563328 0.3003988862037659 0.12972699105739596 0.18772807717323306 54.94522274463424 45.0 0.0 no 15005 chrXVI_400392 36618 essential YPL082C 3672 - TCGGCGATACCAGCTTCTAA D|1231|H D|1231|N A|1230|P A|1230|T MOT1 Modifier of Transcription 1867.0 0 0 0 0 -0.3361326737267394 P32333 0.8342450261116028 0.9383370280265808 0.9908030033111572 0.9480339884757996 0.01828131265938282 0.16584277153015134 1.0 0.02427703887224197 51.10141169956694 50.0 0.0 no 15006 chrXVI_400489r 36620 essential YPL082C 3572 + TTTCTTAATAGTTCCACTTT F|1192|L silent|TTC>TTT|F|1192 MOT1 Modifier of Transcription 1867.0 0 0 0 0 0.3229683245531716 P32333 0.9324849843978882 0.013687921687960623 41.83671484102524 25.0 0.0 no 15007 chrXVI_400645r 36622 essential YPL082C 3416 + GGCTAAAATTTCCTCCGTGG A|1140|G A|1140|V MOT1 Modifier of Transcription 1867.0 0 0 0 0 -1.0780539047521684 P32333 0.9300230145454408 0.9144520163536072 0.012564904987812042 0.1368495672941208 49.716386854201744 50.0 0.0 no 15008 chrXVI_400648r 36623 essential YPL082C 3413 + TCTGGCTAAAATTTCCTCCG L|1139|V silent|CTG>TTG|L|1139 A|1140|G A|1140|V MOT1 Modifier of Transcription 1867.0 0 0 0 0 0.6204231182964958 P32333 0.971862018108368 0.9300230145454408 0.9144520163536072 0.3319444954395294 0.012564904987812042 0.1368495672941208 47.74279680941595 45.0 0.0 no 15009 chrXVI_400666r 36624 essential YPL082C 3395 + TGCAAGAACTTTTGCTGATC A|1133|G A|1133|V MOT1 Modifier of Transcription 1867.0 0 0 0 0 0.6479943242640089 P32333 0.9219629764556884 0.921422004699707 0.04042718559503555 0.02580049633979797 43.11982641139365 40.0 0.0 no 15010 chrXVI_401072 36628 essential YPL082C 2992 - TTCTTTATATTCTGCATTTA E|1004|Q E|1004|K MOT1 Modifier of Transcription 1867.0 0 0 0 0 0.3867662144579222 P32333 0.9841179847717284 0.9754040241241456 0.4708082973957062 0.9251806735992432 39.386076702233204 20.0 0.0 no 15011 chrXVI_401263 36632 essential YPL082C 2801 - CCATTAGCGACCTGATAATG M|940|I M|940|I MOT1 Modifier of Transcription 1867.0 0 0 0 0 -1.0620688268865637 P32333 0.8518959879875183 0.8518959879875183 0.0 0.0 45.388472068723964 45.0 0.0 no 15012 chrXVI_401304r 36633 essential YPL082C 2757 + TCATCCATCTTGTTATTTGA S|920|* S|920|L S|921|C S|921|F MOT1 Modifier of Transcription 1867.0 0 0 0 0 -0.0390893290782546 P32333 0.91531902551651 0.9231860041618348 0.8342469930648804 0.14444604516029358 0.0054266396909952155 0.002305242931470275 44.671581676573574 30.0 0.0 no 15013 chrXVI_401345 36634 essential YPL082C 2719 - GCTGCCTGTACGAAGTTTTG S|913|T S|913|N G|912|A G|912|D MOT1 Modifier of Transcription 1867.0 0 0 0 0 0.8665056447428019 P32333 0.9528599977493286 0.9120190143585204 0.998126983642578 0.9744830131530762 0.5870532393455505 0.4870192110538482 0.12149563431739807 0.03680238127708435 50.639893006063176 50.0 0.0 no 15014 chrXVI_401354 36635 essential YPL082C 2710 - ACGAAGTTTTGCGGATTCTT R|910|P R|910|H MOT1 Modifier of Transcription 1867.0 0 0 0 0 -0.9389171611595956 P32333 0.8066669702529907 0.9597560167312622 0.02454439178109169 0.016505304723978043 45.71796516840822 40.0 0.0 no 15015 chrXVI_401431r 36637 essential YPL082C 2630 + GAACAACTCTTACAAACTAT N|878|K silent|AAC>AAT|N|878 N|879|K silent|AAC>AAT|N|879 MOT1 Modifier of Transcription 1867.0 0 0 0 0 0.7768103911870862 P32333 0.9928560256958008 0.9406999945640564 0.5875334143638611 0.284503310918808 35.100248793984925 30.0 0.0 no 15016 chrXVI_401541r 36640 essential YPL082C 2520 + AACGTAGCAATTGTGGTTCA N|841|K silent|AAC>AAT|N|841 MOT1 Modifier of Transcription 1867.0 0 0 0 0 -0.9158351926437848 P32333 0.9690819978713988 0.361531674861908 45.09983404908166 40.0 0.0 no 15017 chrXVI_401548r 36641 essential YPL082C 2513 + ACTACCCAACGTAGCAATTG L|839|V silent|CTA>TTA|L|839 P|840|A P|840|S MOT1 Modifier of Transcription 1867.0 0 0 0 0 -0.26293676776667 P32333 0.9822369813919068 0.8824480175971985 0.8702229857444763 0.03678731620311737 0.0 0.0 46.12227230653883 45.0 0.0 no 15018 chrXVI_401582 36643 essential YPL082C 2482 - TAACATACCTACATCCACAA M|833|I M|833|I MOT1 Modifier of Transcription 1867.0 0 0 0 0 1.2002545598647547 P32333 1.0895199775695799 1.0895199775695799 0.20160333812236786 0.20160333812236786 42.24588445327237 35.0 0.0 no 15019 chrXVI_401596r 36645 essential YPL082C 2465 + AAGCCTACTGGCTACCTTTG S|823|R silent|AGC>AGT|S|823 L|824|V silent|CTA>TTA|L|824 MOT1 Modifier of Transcription 1867.0 0 0 0 0 0.0978393892273542 P32333 0.883575975894928 0.8792809844017029 0.29460328817367554 0.02379398792982101 52.585624576633556 50.0 0.0 no 15020 chrXVI_401608r 36646 essential YPL082C 2453 + GACTCAATGTCAAAGCCTAC T|819|S T|819|I Q|820|E Q|820|* MOT1 Modifier of Transcription 1867.0 0 0 0 0 -0.04482866121774008 P32333 0.9560459852218628 0.8230540156364441 1.089709997177124 0.8567713499069214 0.03232097998261452 0.14770324528217316 44.51452643714322 45.0 0.0 no 15021 chrXVI_401768r 36647 essential YPL082C 2293 + TTTCACAGTTTTGCTCCTCG S|766|* S|766|L Q|767|E Q|767|* MOT1 Modifier of Transcription 1867.0 0 0 0 0 -0.2939783082294367 P32333 0.9267680048942566 1.0216799974441528 0.04778749123215675 1.0 51.75518516805846 45.0 0.0 no 15022 chrXVI_401803r 36649 essential YPL082C 2258 + ATTCTCAACTCCACGTATGT F|754|L silent|TTC>TTT|F|754 S|755|* S|755|L MOT1 Modifier of Transcription 1867.0 0 0 0 0 0.12609394818280162 P32333 0.9865090250968932 0.9195029735565186 0.4710548520088196 0.012343852780759336 47.63522772228527 40.0 0.0 no 15023 chrXVI_401911r 36651 essential YPL082C 2150 + CACTAGAATAATGGGAGCAA T|718|S T|718|I MOT1 Modifier of Transcription 1867.0 0 0 0 0 0.15595549018723093 P32333 0.9441940188407898 0.8687080144882202 1.0 0.12260673940181732 39.728469720232056 40.0 0.0 no 15024 chrXVI_402126 36653 essential YPL082C 1938 - TTCTTTCCCTTTTCCCCTAC K|652|N silent|AAG>AAA|K|652 G|651|A G|651|E MOT1 Modifier of Transcription 1867.0 0 0 0 0 0.3323891135589828 P32333 0.9286360144615172 1.0561499595642092 1.0330400466918943 0.3873003721237183 0.4677829742431641 0.2537266910076141 58.34193048390011 45.0 0.0 no 15025 chrXVI_402141r 36656 essential YPL082C 1920 + CATCTTCTAAATACGCCAGT L|642|V L|642|F L|643|V silent|CTA>TTA|L|643 MOT1 Modifier of Transcription 1867.0 0 0 0 0 1.4841845477462232 P32333 0.8747580051422119 0.7812420129776001 0.9439110159873962 0.15799550712108612 0.018257983028888702 1.0 45.286112426675565 40.0 0.0 no 15026 chrXVI_402398r 36658 essential YPL082C 1663 + GCCATTCGATTTCTTCTGTG H|556|D H|556|Y silent|CGC>CGG|R|555 silent|CGC>CGT|R|555 MOT1 Modifier of Transcription 1867.0 0 0 0 0 0.4758057730101836 P32333 0.8362259864807129 0.8757359981536865 0.01571270078420639 0.15084321796894073 50.7678871533575 45.0 0.0 no 15027 chrXVI_402610r 36660 essential YPL082C 1451 + CAACTCTACCATAGAAATTT N|485|K silent|AAC>AAT|N|485 S|486|C S|486|F MOT1 Modifier of Transcription 1867.0 0 0 0 0 0.15126923909810094 P32333 0.98750901222229 0.8195310235023499 0.915573000907898 0.8033440709114075 0.052169110625982285 0.05996580421924591 37.78252769932851 30.0 0.0 no 15028 chrXVI_402641 36662 essential YPL082C 1423 - GACAAATTCGCTGGTTATTG V|481|L V|481|I MOT1 Modifier of Transcription 1867.0 0 0 0 0 -5.140955804801312 P32333 0.9022639989852904 0.9180020093917848 0.12793423235416412 0.2942984998226166 42.083005782966104 40.0 0.0 yes 15029 chrXVI_402727 36663 essential YPL082C 1337 - TACGGACAACGTTTTCTAAA R|452|P R|452|H V|451|L V|451|I MOT1 Modifier of Transcription 1867.0 0 0 0 0 0.8361014892653095 P32333 0.9714949727058412 0.9817339777946472 0.972046971321106 0.9625499844551086 0.2506149113178253 0.11094287782907486 0.4828088879585266 1.0 39.00456263263135 35.0 0.0 no 15030 chrXVI_402734 36664 essential YPL082C 1330 - AACGTTTTCTAAAAGGCCAT V|450|L V|450|I MOT1 Modifier of Transcription 1867.0 0 0 0 0 0.9432988475049472 P32333 0.9140189886093141 0.9581850171089172 0.21904197335243225 0.38958394527435297 41.891294374908064 35.0 0.0 no 15031 chrXVI_402750r 36665 essential YPL082C 1311 + ACAAATTTCCTATTTGCCCA T|438|R T|438|I MOT1 Modifier of Transcription 1867.0 0 0 0 0 -0.055002675973019284 P32333 0.97578102350235 0.917952001094818 0.4725107252597809 0.3601098954677582 47.49844285231512 35.0 0.0 no 15032 chrXVI_402794 36666 essential YPL082C 1270 - AATCCCTAAAAGCCCTCCAT silent|GGG>GGC|G|429 silent|GGG>GGA|G|429 G|429|A G|429|E MOT1 Modifier of Transcription 1867.0 0 0 0 0 -0.8533855417413371 P32333 0.8609769940376282 0.7581459879875183 0.0 0.0 51.50466772944441 45.0 0.0 no 15033 chrXVI_403003r 36672 essential YPL082C 1058 + TCTACTTACAGTATTTGCAT L|354|V silent|CTA>TTA|L|354 L|355|V L|355|F MOT1 Modifier of Transcription 1867.0 0 0 0 0 0.07232783593335658 P32333 0.8882960081100464 0.8876230120658875 0.8259660005569458 0.031110865995287895 1.0 0.14595985412597656 42.603494267267536 30.0 0.0 no 15034 chrXVI_403006 36673 essential YPL082C 1058 - ATGCAAATACTGTAAGTAGA A|359|P A|359|T MOT1 Modifier of Transcription 1867.0 0 0 0 0 -0.32143742786242485 P32333 0.8781890273094177 0.9053120017051696 0.08044777065515518 0.38962286710739136 36.7254184790865 30.0 0.0 no 15035 chrXVI_403057 36675 essential YPL082C 1007 - TCCTCAGGTTGTTCTCCTCT R|342|T R|342|K R|342|S silent|AGG>AGA|R|342 MOT1 Modifier of Transcription 1867.0 0 0 0 0 -0.01375883841783576 P32333 0.9399489760398864 0.9914010167121888 0.9303569793701172 0.16305096447467804 1.0 0.13492999970912933 60.17989278898767 50.0 0.0 no 15036 chrXVI_403093r 36677 essential YPL082C 968 + ACATGCTTATGGAGTCAGCA H|324|D H|324|Y A|325|G A|325|V MOT1 Modifier of Transcription 1867.0 0 0 0 0 -0.4608625169907178 P32333 0.7854419946670532 0.8499100208282471 1.0125900506973269 0.9148579835891724 0.19941236078739166 0.05866015329957008 1.0 0.019299047067761418 49.94294936744677 45.0 0.0 no 15037 chrXVI_403094r 36678 essential YPL082C 967 + AACATGCTTATGGAGTCAGC H|324|D H|324|Y A|325|G A|325|V MOT1 Modifier of Transcription 1867.0 0 0 0 0 -0.7560819174948917 P32333 0.7854419946670532 0.8499100208282471 1.0125900506973269 0.9148579835891724 0.19941236078739166 0.05866015329957008 1.0 0.019299047067761418 46.91227075466099 45.0 0.0 no 15038 chrXVI_403274 36682 essential YPL082C 790 - TATCATTAGTTTACTTTCAT M|269|I M|269|I MOT1 Modifier of Transcription 1867.0 0 0 0 0 -0.02458157354777705 P32333 0.9967550039291382 0.9967550039291382 0.2131018042564392 0.2131018042564392 37.826409649887644 20.0 0.0 no 15039 chrXVI_403312r 36684 essential YPL082C 749 + TAACCAGCTAAATCCCAAAC N|251|K silent|AAC>AAT|N|251 Q|252|E Q|252|* MOT1 Modifier of Transcription 1867.0 0 1 0 0 -0.1699253735160972 P32333 0.9975939989089966 1.0074199438095093 0.9230974912643432 1.0 42.39311518730318 40.0 0.0 no 15040 chrXVI_403407 36686 essential YPL082C 657 - GAACTTTCCGTTATATCTAC S|225|T S|225|N MOT1 Modifier of Transcription 1867.0 0 1 0 0 0.6859935797861686 P32333 0.8912150263786316 0.8842790126800537 0.6390760540962219 0.5193306803703308 42.143082043230095 35.0 0.0 no 15041 chrXVI_403487r 36688 essential YPL082C 574 + ATGCTAACAAGAAGTCAGCA A|193|G A|193|V MOT1 Modifier of Transcription 1867.0 0 0 0 0 -2.8355428919649586 P32333 1.0128300189971924 0.925665020942688 0.3767910301685333 0.2793075442314148 42.53455860213376 40.0 0.0 yes 15042 chrXVI_403682r 36691 essential YPL082C 379 + ACCTCAGTTCTCTGTCTGAT L|128|V L|128|F H|127|Q silent|CAC>CAT|H|127 MOT1 Modifier of Transcription 1867.0 0 0 0 0 0.3372828804645321 P32333 0.9588509798049928 0.9583370089530944 1.000540018081665 0.5158887505531311 0.5309061408042908 0.6153879165649414 53.52940268392274 45.0 0.0 no 15043 chrXVI_403711r 36692 essential YPL082C 350 + TCAGTTGAATCTCTTACAGG Q|118|E Q|118|* MOT1 Modifier of Transcription 1867.0 0 0 0 0 -0.4267654252595915 P32333 1.0216799974441528 1.0 43.5170618830989 40.0 0.0 no 15044 chrXVI_403782 36693 essential YPL082C 282 - TTCACCTGAGCATTATCCAA silent|GTG>GTC|V|100 silent|GTG>GTA|V|100 V|100|L V|100|M MOT1 Modifier of Transcription 1867.0 0 0 0 1 -0.291240172442124 P32333 0.969856023788452 0.9378550052642822 0.335601419210434 0.046961605548858636 48.36512167798118 40.0 0.0 no 15045 chrXVI_403824 36695 essential YPL082C 240 - CCTACCAAGTCAGATTCATT G|87|R G|87|S V|86|L V|86|I MOT1 Modifier of Transcription 1867.0 0 1 0 0 0.10517279570718124 P32333 0.9358969926834106 0.9776149988174438 1.0029499530792236 1.0026299953460691 0.4839437603950501 0.7234874963760376 0.3174325227737427 0.1892419010400772 47.382593518343924 40.0 0.0 no 15046 chrXVI_403910 36699 essential YPL082C 154 - CCATTTCTTCACTAGTAAAA W|58|S W|58|* K|56|N silent|AAG>AAA|K|56 MOT1 Modifier of Transcription 1867.0 0 0 0 0 0.6880895222639299 P32333 0.7216259837150574 0.8910409808158875 0.0 0.00676366128027439 39.57447977838325 30.0 0.0 no 15047 chrXVI_404035 36706 essential YPL082C 29 - TCTCTATTAATATTACCTGC E|16|Q E|16|K E|16|D silent|GAG>GAA|E|16 MOT1 Modifier of Transcription 1867.0 0 0 0 0 0.3956475397411544 P32333 0.8706480264663696 0.8597999811172485 0.9537339806556702 0.03283693641424179 0.025668391957879063 0.3814531266689301 41.309957162776705 30.0 0.0 no 15048 chrXVI_404002 36707 essential YPL082C 62 - CAGCCATGTTCCGGACTACT A|27|P A|27|T M|26|I M|26|I MOT1 Modifier of Transcription 1867.0 0 0 0 0 -0.5323417600708227 P32333 0.8521810173988342 0.7829220294952393 0.9754710197448729 0.9754710197448729 0.0 0.0 0.26430079340934753 0.26430079340934753 55.52508370264883 55.00000000000001 0.0 no 15049 chrXVI_410583 36710 essential YPL076W 140 + TGCTCGCGCTCAAATTAGGT A|48|G A|48|V R|49|G R|49|C 0 0 0 0 0.14973559671807726 P46961 0.9484469890594482 0.9504740238189696 0.8994590044021606 0.8926740288734436 0.3975276350975037 0.2994259297847748 0.344611257314682 0.17390674352645874 50.90730789480006 50.0 1.0 no 15050 chrXVI_410751 36711 essential YPL076W 308 + CCCTCTATTGTCCTCATTCA P|104|R P|104|L P|104|A P|104|S 0 0 0 0 -0.5590098216722982 P46961 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.6669517159461975 0.2647067904472351 0.5801383852958679 0.5570265650749207 55.63352146855522 45.0 1.0 no 15051 chrXVI_410751r 36712 essential YPL076W 311 - CCATGAATGAGGACAATAGA M|110|I M|110|I 0 0 0 0 0.5456663081554121 P46961 0.9553959965705872 0.9553959965705872 0.4230784773826599 0.4230784773826599 40.19532047502372 40.0 1.0 no 15052 chrXVI_410752r 36713 essential YPL076W 312 - TCCATGAATGAGGACAATAG M|110|I M|110|I D|111|H D|111|N 0 0 0 0 0.2491170789883893 P46961 0.9553959965705872 0.9553959965705872 0.9486550092697144 0.956179976463318 0.4230784773826599 0.4230784773826599 0.2330215722322464 0.6987127065658569 39.90697599370424 40.0 1.0 no 15053 chrXVI_410762r 36714 essential YPL076W 322 - AGACTTTACGTCCATGAATG K|113|N silent|AAG>AAA|K|113 0 0 0 0 0.4093915724683981 P46961 0.9355990290641784 0.012012637220323086 42.815506908431026 40.0 1.0 no 15054 chrXVI_410579 36715 essential YPL076W 136 + AAGCTGCTCGCGCTCAAATT A|47|G A|47|V A|48|G A|48|V 0 0 0 0 0.3783969260165327 P46961 0.9484469890594482 0.9504740238189696 0.9484469890594482 0.9504740238189696 0.2582017183303833 0.27926719188690186 0.3975276350975037 0.2994259297847748 50.30718808007964 50.0 1.0 no 15055 chrXVI_410846 36716 essential YPL076W 403 + CAACTGCATCTGATTCCATA T|136|S T|136|I A|137|G A|137|V 0 0 0 0 -0.2591438321766635 P46961 0.9491789937019348 0.9472420215606691 0.9484469890594482 0.9504740238189696 0.184762179851532 0.006736542098224163 0.11748496443033217 0.04092547297477722 46.05344914344807 40.0 1.0 no 15056 chrXVI_410861 36717 essential YPL076W 418 + CCATATGGACATTGTCTTTT silent|TCC>TCG|S|140 silent|TCC>TCT|S|140 0 0 0 0 0.7492695569929895 P46961 45.55465252887427 35.0 1.0 no 15057 chrXVI_410861r 36718 essential YPL076W 421 - CCAAAAAGACAATGTCCATA W|147|S W|147|* 0 0 0 0 0.952010170045834 P46961 0.8858469724655151 0.0 38.71072304418965 35.0 1.0 no 15058 chrXVI_410873 36719 essential YPL076W 430 + TGTCTTTTTGGCTGACCCTA S|145|C S|145|F 0 0 0 0 0.7715744198603445 P46961 0.945252001285553 0.9294660091400146 0.008578313514590263 0.0037631089799106117 54.32166033757528 45.0 1.0 no 15059 chrXVI_411055r 36722 essential YPL076W 615 - TTCGTCACCGATAAATAAGT silent|ACG>ACC|T|211 silent|ACG>ACA|T|211 silent|GTG>GTC|V|210 silent|GTG>GTA|V|210 0 0 0 0 0.12700138022106966 P46961 40.537632392550506 35.0 1.0 no 15060 chrXVI_411056r 36723 essential YPL076W 616 - ATTCGTCACCGATAAATAAG silent|ACG>ACC|T|211 silent|ACG>ACA|T|211 silent|GTG>GTC|V|210 silent|GTG>GTA|V|210 0 0 0 0 -0.017957159161551328 P46961 38.3574733602872 35.0 1.0 no 15061 chrXVI_429946r 36724 essential YPL063W 10 - TCTCACCGAATTTCTTAAAA silent|GTG>GTC|V|9 silent|GTG>GTA|V|9 R|10|T R|10|K TIM50 Translocase of the Inner Mitochondrial membrane 476.0 0 0 0 0 1.0007767311144469 Q02776 38.586838391182475 30.0 1.0 no 15062 chrXVI_429958 36726 essential YPL063W 19 + ATTCGGTGAGACTAAATTCA S|8|W S|8|L TIM50 Translocase of the Inner Mitochondrial membrane 476.0 0 0 0 0 -0.6656747363008946 Q02776 40.434056321473406 35.0 1.0 no 15063 chrXVI_430129r 36729 essential YPL063W 193 - CTTCTCATCGACGTCAACAC E|70|D silent|GAG>GAA|E|70 E|70|Q E|70|K TIM50 Translocase of the Inner Mitochondrial membrane 476.0 0 0 0 0 0.28116615494429475 Q02776 0.5250135660171509 0.4263348579406738 0.6306080222129822 46.93882031859437 50.0 1.0 no 15064 chrXVI_430316 36734 essential YPL063W 377 + TACTGCAATCTACATGGCAA T|127|S T|127|I A|128|G A|128|V TIM50 Translocase of the Inner Mitochondrial membrane 476.0 0 0 0 0 -0.002137205484399725 Q02776 0.4314112663269043 0.4657709002494812 0.08023015409708023 1.0 44.22610442087756 40.0 1.0 no 15065 chrXVI_430347r 36736 essential YPL063W 411 - TTCAATTCTTCAGACTCTTG L|143|F silent|TTG>TTA|L|143 TIM50 Translocase of the Inner Mitochondrial membrane 476.0 0 0 0 0 0.5700644350707548 Q02776 0.05175278335809708 42.351618573990386 35.0 1.0 no 15066 chrXVI_430593 36738 essential YPL063W 654 + CCTGGTGCTGACTACTTCTT P|219|R P|219|L TIM50 Translocase of the Inner Mitochondrial membrane 476.0 0 0 0 0 -0.203471476254738 Q02776 0.0 0.0 1.412919998168945 1.2437599897384644 54.16804177895955 50.0 1.0 no 15067 chrXVI_430593r 36739 essential YPL063W 657 - CCCAAGAAGTAGTCAGCACC L|225|F silent|TTG>TTA|L|225 G|226|R G|226|S TIM50 Translocase of the Inner Mitochondrial membrane 476.0 0 0 0 0 0.7506400775043741 Q02776 0.0 0.5723059773445129 0.2987450063228607 1.8636000156402588 -1.5536600351333618 -0.9373800158500672 52.56355552134561 55.00000000000001 1.0 no 15068 chrXVI_430654r 36740 essential YPL063W 718 - GTCAGAGTACATCATATAGT D|246|H D|246|N TIM50 Translocase of the Inner Mitochondrial membrane 476.0 0 0 0 0 1.4298655809358565 Q02776 0.008187913335859777 0.018522953614592552 0.12330000102519988 0.06809999793767929 42.670936779598435 35.0 1.0 no 15069 chrXVI_430844 36741 essential YPL063W 905 + ACCTGAAAATGCTATTCCAA P|303|R P|303|L P|303|A P|303|S TIM50 Translocase of the Inner Mitochondrial membrane 476.0 0 0 0 0 0.7323511550756954 Q02776 0.012980950064957142 0.008942140266299248 0.038888514041900635 0.02342026494443417 1.8040200471878047 1.7070399522781372 2.0886600017547607 2.4843199253082275 42.04174765159405 35.0 1.0 no 15070 chrXVI_430845r 36742 essential YPL063W 909 - TCCATTGGAATAGCATTTTC M|309|I M|309|I E|310|Q E|310|K TIM50 Translocase of the Inner Mitochondrial membrane 476.0 0 0 0 0 -0.25734144907251066 Q02776 0.9164206385612488 0.9164206385612488 0.2553611397743225 0.8184787631034851 0.16954000294208527 0.16954000294208527 -0.06821999698877335 -0.417499989271164 0.150859996676445 0.150859996676445 43.92990558817217 35.0 1.0 no 15071 chrXVI_430852 36743 essential YPL063W 913 + ATGCTATTCCAATGGAGCCA A|306|G A|306|V TIM50 Translocase of the Inner Mitochondrial membrane 476.0 0 0 0 0 -0.09191193871191776 Q02776 0.0698525458574295 0.02530954591929913 1.461899995803833 2.4984800815582275 1.503239989280701 0.5892999768257141 51.274591767402065 45.0 1.0 no 15072 chrXVI_430869r 36745 essential YPL063W 933 - TCATCAGCTTCACCATTCCA D|318|H D|318|N D|317|H D|317|N TIM50 Translocase of the Inner Mitochondrial membrane 476.0 0 0 0 0 -0.1939880005232955 Q02776 0.025617804378271103 0.07663682103157042 0.1227377876639366 0.4512926638126373 -0.4366399943828583 0.02342000044882297 2.563159942626953 2.24180006980896 54.178489854741876 45.0 1.0 no 15073 chrXVI_430925 36747 essential YPL063W 986 + CCTTGCCACTCAACAAACCA L|330|V L|330|F A|331|G A|331|V TIM50 Translocase of the Inner Mitochondrial membrane 476.0 0 0 0 0 -0.7479633152803682 Q02776 0.26815491914749146 0.029827576130628582 0.05172030255198479 0.4651612639427185 1.6121599674224854 5.343279838562012 1.5740400552749634 2.0776801109313965 1.8885400295257568 4.043179988861084 50.588356357971115 50.0 1.0 no 15074 chrXVI_430930r 36748 essential YPL063W 994 - AACATCCTTGGTTTGTTGAG V|338|L V|338|I D|337|H D|337|N TIM50 Translocase of the Inner Mitochondrial membrane 476.0 0 0 0 0 -0.3319789195819381 Q02776 0.0 0.0 0.0 0.0 0.3483799993991852 0.0072800000198185435 2.7385001182556152 1.0 45.88023415642374 40.0 1.0 no 15075 chrXVI_430956r 36749 essential YPL063W 1020 - TCTTCAAAGCTGTTCAAGAT D|347|H D|347|N E|346|Q E|346|K TIM50 Translocase of the Inner Mitochondrial membrane 476.0 0 0 0 0 0.6762560518862684 Q02776 0.1549936830997467 0.9171904921531676 0.4696744382381439 0.5877990126609802 0.3834599852561951 -0.19043999910354611 -0.7516599893569946 -0.6005200147628784 41.84706015860672 35.0 1.0 no 15076 chrXVI_467269r 36750 high_effect YPL045W 12 - AATCTTTCCCAGTCGAAGCT R|10|T R|10|K VPS16 Vacuolar Protein Sorting 798.0 0 0 0 0 1.02328446669415 Q03308 0.06615083664655685 1.0 50.885553656824634 45.0 1.0 no 15077 chrXVI_467318r 36752 high_effect YPL045W 61 - TGGCCATTTTAATTCGCCAA W|26|C W|26|* W|26|S W|26|* VPS16 Vacuolar Protein Sorting 798.0 0 0 0 0 0.3333084699328842 Q03308 0.06507822871208191 0.31245535612106323 48.5130748027695 40.0 1.0 no 15078 chrXVI_467366r 36753 high_effect YPL045W 109 - CGCGATAACAGTTAATGACA A|43|P A|43|T VPS16 Vacuolar Protein Sorting 798.0 0 0 0 0 0.5396968450330395 Q03308 0.021889716386795044 0.03488222882151604 40.42022958334633 40.0 1.0 no 15079 chrXVI_467586 36757 high_effect YPL045W 326 + CCCAACCATTGATACTATCT P|110|R P|110|L P|110|A P|110|S VPS16 Vacuolar Protein Sorting 798.0 0 0 0 0 -0.028404716160352506 Q03308 0.4706195294857025 0.2708912789821625 0.6791766285896301 0.8247398138046265 47.525458129920814 40.0 1.0 no 15080 chrXVI_467727r 36759 high_effect YPL045W 470 - AGTCATCATTGCAACTCCAG D|163|H D|163|N D|162|H D|162|N VPS16 Vacuolar Protein Sorting 798.0 0 0 0 0 0.3053798985220874 Q03308 0.09467844665050508 0.5854160189628601 0.1393968015909195 0.5307676792144775 48.688365756712535 45.0 1.0 no 15081 chrXVI_467750r 36761 high_effect YPL045W 493 - ATCAACATCCAGTAAAATGA D|171|H D|171|N V|170|L V|170|I VPS16 Vacuolar Protein Sorting 798.0 0 0 0 0 1.1334449630507724 Q03308 0.07949680835008621 0.8895893692970276 0.3645437955856323 0.5850652456283569 37.1355747268413 30.0 1.0 no 15082 chrXVI_467779 36762 high_effect YPL045W 519 + TATCAAGTAAGCACCTCGAA Q|175|E Q|175|* VPS16 Vacuolar Protein Sorting 798.0 0 0 0 0 1.2783803635580928 Q03308 0.7153832912445068 43.08500148583874 40.0 1.0 no 15083 chrXVI_467780 36763 high_effect YPL045W 520 + ATCAAGTAAGCACCTCGAAC Q|175|E Q|175|* VPS16 Vacuolar Protein Sorting 798.0 0 0 0 0 1.2615323205290234 Q03308 0.7153832912445068 44.02459594786063 45.0 1.0 no 15084 chrXVI_467781 36764 high_effect YPL045W 521 + TCAAGTAAGCACCTCGAACG Q|175|E Q|175|* VPS16 Vacuolar Protein Sorting 798.0 0 0 0 0 0.06287998809517215 Q03308 0.7153832912445068 45.16674308018661 50.0 1.0 no 15085 chrXVI_467792r 36765 high_effect YPL045W 535 - CTTCAATAGTGCCCCGTTCG L|184|F silent|TTG>TTA|L|184 VPS16 Vacuolar Protein Sorting 798.0 0 0 0 0 0.8472965733668119 Q03308 0.44262459874153137 54.794307127273505 55.00000000000001 1.0 no 15086 chrXVI_467953r 36769 high_effect YPL045W 696 - CCACACCAACATATATCATC C|238|S C|238|Y G|239|R G|239|S VPS16 Vacuolar Protein Sorting 798.0 0 0 0 0 -0.3889093171532928 Q03308 0.0 0.0 0.009181004948914051 0.17604978382587433 44.16567832321783 40.0 1.0 no 15087 chrXVI_468148 36773 high_effect YPL045W 888 + ACTTCTAATATATTTAGAAT T|297|S T|297|I S|298|C S|298|F VPS16 Vacuolar Protein Sorting 798.0 0 0 0 0 0.2397374701900561 Q03308 0.0 0.0 0.02597183734178543 0.015925515443086624 31.178091817403303 15.0 1.0 no 15088 chrXVI_468176r 36774 high_effect YPL045W 919 - AACAAGCATTGCACCAGGCT V|313|L V|313|I M|311|I M|311|I VPS16 Vacuolar Protein Sorting 798.0 0 0 0 0 0.2837382350492696 Q03308 1.0 0.06428799033164978 1.0 1.0 51.40525663102017 50.0 1.0 no 15089 chrXVI_468198 36775 high_effect YPL045W 938 + TGACTCATTTAGTTTACTGG D|314|E silent|GAC>GAT|D|314 S|315|* S|315|L VPS16 Vacuolar Protein Sorting 798.0 0 0 0 0 0.4746947631864453 Q03308 0.0 0.009930239990353584 42.03497652690498 35.0 1.0 no 15090 chrXVI_468469 36777 high_effect YPL045W 1209 + TACAGGTGTATTTCTTTGAA Y|404|* silent|TAC>TAT|Y|404 VPS16 Vacuolar Protein Sorting 798.0 0 0 0 0 -0.8065440013544329 Q03308 40.726129738252276 30.0 1.0 no 15091 chrXVI_468553 36779 high_effect YPL045W 1293 + GCCAATGAACGATTTCTGTT silent|GCC>GCG|A|432 silent|GCC>GCT|A|432 A|432|G A|432|V VPS16 Vacuolar Protein Sorting 798.0 0 0 0 0 0.3669097427041447 Q03308 0.12756189703941345 0.7140043377876282 45.13835716775014 40.0 1.0 no 15092 chrXVI_468619r 36782 high_effect YPL045W 1362 - AACTCATCATCTTCCATGTC E|460|D silent|GAG>GAA|E|460 E|460|Q E|460|K VPS16 Vacuolar Protein Sorting 798.0 0 0 0 0 0.5464295254708207 Q03308 0.5289574265480042 0.4842325747013092 0.6431155204772949 47.4022257694856 40.0 1.0 no 15093 chrXVI_469981 36788 essential YPL043W 42 + GTCTCAAAACAAAATGACGA silent|GTC>GTG|V|15 silent|GTC>GTT|V|15 S|16|* S|16|L NOP4 NucleOlar Protein 685.0 0 0 0 1 -1.367034056143258 P37838 34.999994925395306 35.0 1.0 no 15094 chrXVI_470038r 36790 essential YPL043W 102 - TGCTCATCTGTGACATCCTG E|40|D silent|GAG>GAA|E|40 E|40|Q E|40|K NOP4 NucleOlar Protein 685.0 0 0 0 0 -2.6437345934715144 P37838 0.2640911042690277 0.031682752072811134 0.024940237402915955 52.23718486897684 50.0 1.0 yes 15095 chrXVI_470145 36795 essential YPL043W 206 + GTTCGTTAGTTTTGCTGTAG F|70|L silent|TTC>TTT|F|70 NOP4 NucleOlar Protein 685.0 0 0 0 0 0.08729706685153335 P37838 0.0 47.613789865109254 40.0 1.0 no 15096 chrXVI_470172 36796 essential YPL043W 233 + CACAAAAGAAGCCCTAGCTA T|79|R T|79|I NOP4 NucleOlar Protein 685.0 0 0 0 0 -0.7361180781339373 P37838 0.03532090038061142 0.08630399405956267 45.07799964587826 45.0 1.0 no 15097 chrXVI_470256 36798 essential YPL043W 317 + TTCAAAGAAAACATCAGAAG S|107|* S|107|L NOP4 NucleOlar Protein 685.0 0 0 0 0 -1.2947597373125919 P37838 0.0941241979598999 30.80208657601304 30.0 1.0 no 15098 chrXVI_470319r 36799 essential YPL043W 383 - CGTCCTCATCTTCATTGTTC D|134|H D|134|N E|133|D silent|GAG>GAA|E|133 NOP4 NucleOlar Protein 685.0 0 0 0 0 0.4928540630723225 P37838 51.767946969289426 45.0 1.0 no 15099 chrXVI_470360r 36800 essential YPL043W 424 - TTTCGGTTTACCTTTTAGCA silent|CCG>CCC|P|147 silent|CCG>CCA|P|147 NOP4 NucleOlar Protein 685.0 0 0 0 0 0.4210890823843012 P37838 48.289879787882 35.0 1.0 no 15100 chrXVI_470561r 36806 essential YPL043W 625 - ACCATCAATTTTCAAGTCTT G|215|R G|215|S G|215|A G|215|D NOP4 NucleOlar Protein 685.0 0 0 0 0 0.31568671542018434 P37838 0.0 0.0 0.0 0.0 42.78277577460858 30.0 1.0 no 15101 chrXVI_470560 36807 essential YPL043W 621 + ACCAAAGACTTGAAAATTGA silent|ACC>ACG|T|208 silent|ACC>ACT|T|208 T|208|S T|208|I NOP4 NucleOlar Protein 685.0 0 0 0 0 -0.2045641439849764 P37838 0.8033925294876099 0.2335024029016495 34.99207516480385 30.0 1.0 no 15102 chrXVI_470777 36810 essential YPL043W 838 + AACGTAAAGCACAAAACAAA R|281|G R|281|C NOP4 NucleOlar Protein 685.0 0 0 0 0 0.838678784268678 P37838 0.37737321853637695 0.055051255971193314 32.02788915710579 30.0 1.0 no 15103 chrXVI_470829r 36812 essential YPL043W 893 - ATTCTTCAGTGGCATCATAA E|304|Q E|304|K E|303|Q E|303|K NOP4 NucleOlar Protein 685.0 0 0 0 0 -0.6749239284418233 P37838 0.0324322022497654 0.025532426312565804 0.2889170050621033 0.2964803576469421 45.01935140776925 35.0 1.0 no 15104 chrXVI_470898 36815 essential YPL043W 959 + ACCTGTTATCGATAAGTCTA P|321|R P|321|L P|321|A P|321|S NOP4 NucleOlar Protein 685.0 0 1 0 0 0.3070689881730704 P37838 0.038486316800117486 0.4011598825454712 0.3584467172622681 0.06760654598474503 43.73173064717946 35.0 1.0 no 15105 chrXVI_470916 36819 essential YPL043W 977 + TACGGGGTTGGCTAAAGGTA T|327|R T|327|M NOP4 NucleOlar Protein 685.0 0 1 0 0 -1.2064557677028542 P37838 0.0 0.0 48.920051964454615 50.0 1.0 no 15106 chrXVI_471034 36823 essential YPL043W 1095 + ATGCCTGAGTATGTGTATGA P|367|A P|367|S P|367|R P|367|L NOP4 NucleOlar Protein 685.0 0 0 0 0 -0.5367453293073585 P37838 1.0 0.6601892113685608 0.09432099014520644 0.10086683928966522 47.589944851125786 40.0 1.0 no 15107 chrXVI_471008r 36824 essential YPL043W 1072 - ATCATCACCTATCAATAAAG D|364|H D|364|N D|363|H D|363|N NOP4 NucleOlar Protein 685.0 0 0 0 0 0.4689982616787135 P37838 0.0157222468405962 0.20265302062034607 0.012038953602313995 0.1683012843132019 36.98571411255648 30.0 1.0 no 15108 chrXVI_471037r 36825 essential YPL043W 1101 - CGACCTTCATACACATACTC G|373|A G|373|D G|373|R G|373|S NOP4 NucleOlar Protein 685.0 0 1 0 0 -1.421855087011895 P37838 0.0 0.0 0.0 0.0 45.94742841232397 45.0 1.0 no 15109 chrXVI_471068r 36826 essential YPL043W 1132 - TCTTACTAACGTTGGAGTAA R|384|T R|384|K V|383|L V|383|I NOP4 NucleOlar Protein 685.0 0 1 0 0 0.6955309663260502 P37838 0.01676248200237751 0.452691376209259 0.2960622310638428 0.18469224870204928 40.54977868418547 35.0 1.0 no 15110 chrXVI_471072 36827 essential YPL043W 1133 + TACTCCAACGTTAGTAAGAG T|379|S T|379|I P|380|A P|380|S NOP4 NucleOlar Protein 685.0 1 Series([], Name: modification, dtype: object) 0 0 0 -1.0269272013886557 P37838 0.5707924365997314 0.015035530552268028 0.7970436215400696 0.7645216584205627 41.38037970557895 40.0 1.0 no 15111 chrXVI_471125r 36831 essential YPL043W 1189 - ACCTAGGGCCTCCTTTCTTT G|403|R G|403|S G|403|A G|403|D NOP4 NucleOlar Protein 685.0 0 0 0 0 0.25579523938512155 P37838 0.0 0.0 0.0 0.0 59.90989416144083 50.0 1.0 no 15112 chrXVI_471140r 36832 essential YPL043W 1204 - TTCGCCTGGCGCTTTACCTA E|408|Q E|408|K G|407|A G|407|D NOP4 NucleOlar Protein 685.0 0 0 0 0 -0.5810842050727607 P37838 0.09106313437223433 0.23167239129543304 0.2300219833850861 0.12593379616737366 58.50541102512744 55.00000000000001 1.0 no 15113 chrXVI_471175 36834 essential YPL043W 1236 + AACTTATATTTGCTGAATGA N|413|K silent|AAC>AAT|N|413 NOP4 NucleOlar Protein 685.0 0 0 0 0 0.6422822548712827 P37838 1.0 36.28981041330745 25.0 1.0 no 15114 chrXVI_471346r 36838 essential YPL043W 1410 - GCTTTATCATTCATTGCTCT A|477|P A|477|T NOP4 NucleOlar Protein 685.0 0 0 0 0 0.6363146423329699 P37838 0.2808306813240051 0.3497316539287567 48.305682655660924 35.0 1.0 no 15115 chrXVI_492221 36839 high_effect YPL031C 686 - ACTTTGTTACACTGGGCCAT K|235|N silent|AAG>AAA|K|235 PHO85 PHOsphate metabolism 305.0 0 0 0 0 0.18910743010030376 P17157 51.951498959504995 45.0 0.0 no 15116 chrXVI_492279 36842 high_effect YPL031C 628 - TTTCAGTTGTTCTTCGTCGT silent|CTG>CTC|L|215 silent|CTG>CTA|L|215 PHO85 PHOsphate metabolism 305.0 0 0 0 0 0.2682237452410099 P17157 50.729915437775105 40.0 0.0 no 15117 chrXVI_492357r 36847 high_effect YPL031C 547 + ACTCCACATCCATTGATATA S|184|C S|184|F Y|183|* silent|TAC>TAT|Y|183 PHO85 PHOsphate metabolism 305.0 0 0 0 0 -0.7024120185131851 P17157 45.856022786770716 35.0 0.0 no 15118 chrXVI_492624 36851 high_effect YPL031C 283 - CCCTCTTGGTGTGTTGCCCA G|101|R G|101|R G|101|A G|101|E PHO85 PHOsphate metabolism 305.0 0 0 0 0 -0.8640318967098958 P17157 64.8862349730584 60.0 0.0 no 15119 chrXVI_492624r 36852 high_effect YPL031C 280 + CCGTGGGCAACACACCAAGA silent|ACC>ACG|T|94 silent|ACC>ACT|T|94 PHO85 PHOsphate metabolism 305.0 0 0 0 0 -0.3252564419821589 P17157 52.95725552156131 60.0 0.0 no 15120 chrXVI_492640r 36854 high_effect YPL031C 264 + TACATGGATTCCCGCACCGT Y|89|* silent|TAC>TAT|Y|89 PHO85 PHOsphate metabolism 305.0 0 0 0 0 -0.9567291583380916 P17157 56.06535825765946 55.00000000000001 0.0 no 15121 chrXVI_492695r 36856 high_effect YPL031C 209 + CACAGAGAACAAGTTGACTT T|71|R T|71|I PHO85 PHOsphate metabolism 305.0 0 0 0 0 -0.18465331057925988 P17157 40.20499273524597 40.0 0.0 no 15122 chrXVI_492812 36859 high_effect YPL031C 95 - AATCCAGTTTTACCTCTTTC D|38|H D|38|N silent|CTG>CTC|L|37 silent|CTG>CTA|L|37 PHO85 PHOsphate metabolism 305.0 0 0 0 0 -1.801735437062566 P17157 47.18348076568475 35.0 0.0 no 15123 chrXVI_492858 36860 high_effect YPL031C 49 - GTTCAGTCCCTTGTACACTG silent|CTG>CTC|L|22 silent|CTG>CTA|L|22 PHO85 PHOsphate metabolism 305.0 0 0 0 0 -0.04195961833350653 P17157 54.28040889085099 50.0 0.0 no 15124 chrXVI_492865r 36861 high_effect YPL031C 39 + ACGTATGCCACAGTGTACAA T|14|R T|14|M PHO85 PHOsphate metabolism 305.0 0 1 0 0 0.71958610375774 P17157 48.125355495405465 45.0 0.0 no 15125 chrXVI_492866r 36862 high_effect YPL031C 38 + TACGTATGCCACAGTGTACA T|14|R T|14|M PHO85 PHOsphate metabolism 305.0 0 1 0 0 0.021793680694533246 P17157 49.18705502065609 45.0 0.0 no 15126 chrXVI_498120 36863 essential YPL028W 24 + TCGACTGCCAGAACCCCAAT S|9|W S|9|L T|10|S T|10|I ERG10 ERGosterol biosynthesis 398.0 0 0 0 0 -6.652281431409936 P41338 0.9288619756698608 0.9298099875450134 0.9491789937019348 0.9472420215606691 0.0026177044492214922 0.01777362823486328 0.0816878005862236 0.04003038257360458 53.95339661924788 55.00000000000001 1.0 yes 15127 chrXVI_498158 36864 essential YPL028W 62 + TCTATCCTCCAAGACAGCAG L|22|V silent|CTA>TTA|L|22 S|23|C S|23|F ERG10 ERGosterol biosynthesis 398.0 0 1 0 0 0.4188631578599755 P41338 0.9512209892272948 0.945252001285553 0.9294660091400146 0.006781093310564756 0.04145396128296852 0.02344089187681675 3.144599914550781 50.94505207076333 50.0 1.0 no 15128 chrXVI_498165 36865 essential YPL028W 69 + TCCAAGACAGCAGTGGAATT silent|TCC>TCG|S|24 silent|TCC>TCT|S|24 S|24|C S|24|F ERG10 ERGosterol biosynthesis 398.0 0 0 1 Series([], Name: modification, dtype: object) 0 -0.24526606536431456 P41338 0.945252001285553 0.9294660091400146 0.010801314376294613 0.010176254436373709 -0.01240000035613775 -1.0521999597549438 46.79277648491183 45.0 1.0 no 15129 chrXVI_498322r 36872 essential YPL028W 229 - AACGATATGATTACTCAAAC V|83|L V|83|I ERG10 ERGosterol biosynthesis 398.0 0 0 0 0 0.14878695005452172 P41338 0.9539830088615416 0.9574310183525084 0.4995149075984955 0.3677461743354797 -0.4564000070095062 -0.21619999408721924 33.96220392144687 30.0 1.0 no 15130 chrXVI_498375 36875 essential YPL028W 279 + GCTATGAAGGCAATCATTTT A|94|G A|94|V ERG10 ERGosterol biosynthesis 398.0 0 1 0 0 0.6530515538462571 P41338 0.9484469890594482 0.9504740238189696 1.0 0.002448694780468941 -2.5999999046325684 11.66759967803955 42.810578617702724 35.0 1.0 no 15131 chrXVI_498406r 36876 essential YPL028W 313 - ATCAGCATTACCACATTTGA D|111|H D|111|N A|110|P A|110|T ERG10 ERGosterol biosynthesis 398.0 0 0 0 0 -0.0603777837558973 P41338 0.9486550092697144 0.956179976463318 0.9573720097541808 0.9523990154266356 0.07238534837961197 0.4403959512710571 0.1587429791688919 0.27552810311317444 1.0687999725341797 -0.2158000022172928 45.33216996896226 35.0 1.0 no 15132 chrXVI_498473 36878 essential YPL028W 377 + CTACATGCCAGCAGCCCGTG Y|127|* silent|TAC>TAT|Y|127 ERG10 ERGosterol biosynthesis 398.0 0 0 0 0 -1.07839195031366 P41338 60.366859913174956 65.0 1.0 no 15133 chrXVI_498598r 36883 essential YPL028W 505 - TCTAGTAATATCCCAATCAC R|175|T R|175|K ERG10 ERGosterol biosynthesis 398.0 0 0 0 0 -1.8053415613114328 P41338 0.932735025882721 0.955805003643036 0.0 0.0 42.64685631616561 35.0 1.0 no 15134 chrXVI_498599r 36884 essential YPL028W 506 - CTCTAGTAATATCCCAATCA R|175|T R|175|K ERG10 ERGosterol biosynthesis 398.0 0 0 0 0 -1.6090399418165562 P41338 0.932735025882721 0.955805003643036 0.0 0.0 44.00551243589945 35.0 1.0 no 15135 chrXVI_498660 36885 essential YPL028W 564 + TCTCAAAAATCTCAAAAGGA Q|190|E Q|190|* S|189|C S|189|F ERG10 ERGosterol biosynthesis 398.0 0 1 0 0 -0.039105996524621586 P41338 0.9590039849281312 0.945252001285553 0.9294660091400146 0.9550292491912842 0.003974037244915961 0.0015020845457911491 33.61117257541377 30.0 1.0 no 15136 chrXVI_498735r 36886 essential YPL028W 642 - TCCTTCGTGACTTGAGTATC K|220|N silent|AAG>AAA|K|220 D|221|H D|221|N ERG10 ERGosterol biosynthesis 398.0 1 Series([], Name: modification, dtype: object) 0 0 0 -1.5868396752205458 P41338 0.9355990290641784 0.9486550092697144 0.956179976463318 0.0719824731349945 0.0 0.0 0.8378000259399414 49.052978339592464 45.0 1.0 no 15137 chrXVI_498843 36888 essential YPL028W 747 + AACGCTTCTCCAATCAACGA N|250|K silent|AAC>AAT|N|250 A|251|G A|251|V ERG10 ERGosterol biosynthesis 398.0 0 1 0 0 -0.5765754870092947 P41338 0.9439849853515624 0.9484469890594482 0.9504740238189696 0.002472816966474056 0.012205708771944046 0.003674381878226996 0.8241999745368958 1.9694000482559204 46.018733518895424 45.0 1.0 no 15138 chrXVI_498921r 36891 essential YPL028W 828 - CAACCTTTGATAATAGCCAA G|282|A G|282|D G|282|R G|282|S ERG10 ERGosterol biosynthesis 398.0 0 0 0 0 -0.9286142021773518 P41338 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 1.0 0.011818259954452516 0.009808545932173729 0.8323157429695129 41.837547121128296 35.0 1.0 no 15139 chrXVI_498958 36892 essential YPL028W 862 + ATCAACCAGCTGATTTTACA Q|289|E Q|289|* P|290|A P|290|S ERG10 ERGosterol biosynthesis 398.0 0 0 0 0 -0.2341811185566398 P41338 0.9590039849281312 0.9562489986419678 0.9498909711837769 0.8677214980125427 0.0 0.0 44.32586719267846 35.0 1.0 no 15140 chrXVI_498959 36893 essential YPL028W 863 + TCAACCAGCTGATTTTACAT Q|289|E Q|289|* P|290|A P|290|S ERG10 ERGosterol biosynthesis 398.0 0 0 0 0 -2.1572633330034487 P41338 0.9590039849281312 0.9562489986419678 0.9498909711837769 0.8677214980125427 0.0 0.0 44.32586719267846 35.0 1.0 yes 15141 chrXVI_512832 36894 essential YPL020C 1327 - TAGCCATCTTCGTGGTGCCA W|448|C W|448|* W|448|S W|448|* ULP1 UbL-specific Protease 621.0 0 0 0 0 -0.20046107338867405 Q02724 0.8858469724655151 0.8858469724655151 0.0 0.0 1.292019963264465 1.481559991836548 1.0314600467681885 1.1255600452423096 0.5726000070571899 1.0710999965667725 59.25081431070987 55.00000000000001 0.0 no 15142 chrXVI_512835r 36895 essential YPL020C 1321 + AGACCTTGGCACCACGAAGA T|442|S T|442|I silent|ACC>ACG|T|442 silent|ACC>ACT|T|442 ULP1 UbL-specific Protease 621.0 0 0 0 0 -0.6775275410028274 Q02724 0.9491789937019348 0.9472420215606691 0.0 0.0 0.6013000011444092 4.051620006561278 0.799560010433197 4.493800163269043 51.87452398428502 55.00000000000001 0.0 no 15143 chrXVI_512921r 36897 essential YPL020C 1235 + TGACCAAGTACAAAAAGCTT D|413|E silent|GAC>GAT|D|413 Q|414|E Q|414|* ULP1 UbL-specific Protease 621.0 0 0 0 0 0.618767848158448 Q02724 0.9532920122146606 0.9590039849281312 1.0 1.0 -0.30382001399993896 0.7595800161361694 38.623641762428974 35.0 0.0 no 15144 chrXVI_512944 36898 essential YPL020C 1215 - TCGTCTTTTTCATTTAATTC D|412|H D|412|N D|411|H D|411|N ULP1 UbL-specific Protease 621.0 0 0 0 0 0.32774208890396866 Q02724 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.10641800612211227 0.11367852985858914 0.014329396188259125 0.029114358127117164 1.2958199977874756 -0.7130399942398071 0.07156000286340714 0.05993999913334847 39.57800958466851 25.0 0.0 no 15145 chrXVI_512961 36899 essential YPL020C 1198 - TTCAGGAACAAGTTTCTTCT E|406|Q E|406|K ULP1 UbL-specific Protease 621.0 0 0 0 0 0.5913306208423388 Q02724 0.956179976463318 0.9475290179252625 0.5072709321975708 0.7761608362197876 0.6463199853897095 0.5173400044441223 43.0704171728687 35.0 0.0 no 15146 chrXVI_513404r 36902 essential YPL020C 752 + GAACATTAACAATACTAAAC N|252|K silent|AAC>AAT|N|252 ULP1 UbL-specific Protease 621.0 0 0 0 0 0.6193574364056011 Q02724 0.9439849853515624 0.9905651211738586 29.522823203083078 25.0 0.0 no 15147 chrXVI_513661 36905 essential YPL020C 498 - TCGATTCTTCTCCTTTTATT E|173|Q E|173|K R|171|T R|171|K ULP1 UbL-specific Protease 621.0 0 1 0 0 -0.3247580695916367 Q02724 0.956179976463318 0.9475290179252625 0.932735025882721 0.955805003643036 0.5518839955329895 0.8784911632537842 0.2295079827308655 0.5980449318885803 45.95680053362713 30.0 0.0 no 15148 chrXVI_513725r 36907 essential YPL020C 431 + TCTACGTGAAAATTATTCCT L|145|V silent|CTA>TTA|L|145 R|146|G R|146|C ULP1 UbL-specific Protease 621.0 0 0 0 0 -0.15236224290418016 Q02724 0.9512209892272948 0.8994590044021606 0.8926740288734436 0.8302944898605347 0.4148269593715668 0.05802055448293686 39.28988607287261 30.0 0.0 no 15149 chrXVI_513956 36912 essential YPL020C 203 - CTTCCATTGATAAAACACGG E|74|Q E|74|K M|73|I M|73|I ULP1 UbL-specific Protease 621.0 0 1 0 0 -0.06107893906239153 Q02724 0.956179976463318 0.9475290179252625 0.9553959965705872 0.9553959965705872 40.17613028023061 40.0 0.0 no 15150 chrXVI_513959r 36913 essential YPL020C 197 + CGACCGCCGTGTTTTATCAA D|67|E silent|GAC>GAT|D|67 R|68|G R|68|C ULP1 UbL-specific Protease 621.0 0 0 0 0 0.009733023710536415 Q02724 0.9532920122146606 0.8994590044021606 0.8926740288734436 51.16692113882221 50.0 0.0 no 15151 chrXVI_514073r 36916 essential YPL020C 83 + TACATATAGGTGTTATCCTC T|29|R T|29|I ULP1 UbL-specific Protease 621.0 0 1 0 0 0.6526965535207321 Q02724 0.9476869702339172 0.9472420215606691 0.0 0.0 44.1261289482963 35.0 0.0 no 15152 chrXVI_514081 36918 essential YPL020C 78 - TAACACCTATATGTAGAAAT C|32|S C|32|Y R|31|S silent|AGG>AGA|R|31 ULP1 UbL-specific Protease 621.0 0 0 0 0 0.5672972313433624 Q02724 0.9421560168266296 0.9290120005607604 0.9087679982185364 0.7747355699539185 34.75227231773732 25.0 0.0 no 15153 chrXVI_514082 36919 essential YPL020C 77 - AACACCTATATGTAGAAATT C|32|S C|32|Y R|31|S silent|AGG>AGA|R|31 ULP1 UbL-specific Protease 621.0 0 0 0 0 0.17011392700709754 Q02724 0.9421560168266296 0.9290120005607604 0.9087679982185364 0.7747355699539185 35.49159537646057 25.0 0.0 no 15154 chrXVI_514086r 36920 essential YPL020C 70 + TCTCCCCAATTTCTACATAT S|25|C S|25|F F|24|L silent|TTC>TTT|F|24 ULP1 UbL-specific Protease 621.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.2773951051605977 Q02724 0.945252001285553 0.9294660091400146 0.9387490153312684 0.0 0.0 0.13267791271209714 48.21398611692808 35.0 0.0 no 15155 chrXVI_521276r 36922 essential YPL016W 265 - ACTATTACTGTTGTTATTGT S|95|T S|95|N SWI1 SWItching deficient 1314.0 0 0 0 0 -0.1052297954078836 P09547 0.9512869715690612 0.9536849856376648 40.3810498947376 25.0 1.0 no 15156 chrXVI_521356r 36923 essential YPL016W 345 - GCATTATTAACGACTGCTGT A|122|P A|122|T SWI1 SWItching deficient 1314.0 0 0 0 0 0.4378161182199664 P09547 0.9573720097541808 0.9523990154266356 45.1942021427285 40.0 1.0 no 15157 chrXVI_521377 36924 essential YPL016W 363 + GCCGCTCCTGCTAATGTTAC silent|GCC>GCG|A|122 silent|GCC>GCT|A|122 A|122|G A|122|V SWI1 SWItching deficient 1314.0 0 0 0 0 -0.5499125858883296 P09547 0.9484469890594482 0.9504740238189696 55.83728644279273 55.00000000000001 1.0 no 15158 chrXVI_521378r 36925 essential YPL016W 367 - ACCGGTAACATTAGCAGGAG G|129|R G|129|S G|129|A G|129|D SWI1 SWItching deficient 1314.0 0 0 0 0 -0.36764688003978935 P09547 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 47.705818274414746 50.0 1.0 no 15159 chrXVI_521383r 36926 essential YPL016W 372 - TTTCCACCGGTAACATTAGC G|130|A G|130|E G|130|R G|130|R SWI1 SWItching deficient 1314.0 0 0 0 0 0.6643721104496623 P09547 0.9499930143356324 0.9438679814338684 0.941340982913971 0.941340982913971 49.23916352454262 45.0 1.0 no 15160 chrXVI_521594r 36933 essential YPL016W 583 - TACATTATCGTTCGCAATTC V|201|L V|201|I SWI1 SWItching deficient 1314.0 0 0 0 0 0.5076555671496149 P09547 0.9539830088615416 0.9574310183525084 0.1928643733263016 0.1492760181427002 42.10401733859715 35.0 1.0 no 15161 chrXVI_521874r 36934 essential YPL016W 863 - TGCTGTTATTACGCATATTA S|294|T S|294|N SWI1 SWItching deficient 1314.0 0 0 0 0 -0.02415591279297141 P09547 0.9512869715690612 0.9536849856376648 0.9908270835876464 0.3483610451221466 42.42008306624052 30.0 1.0 no 15162 chrXVI_521784 36936 essential YPL016W 770 + TTACGCTGCTTCAAATTCAA Y|258|* silent|TAC>TAT|Y|258 A|259|G A|259|V SWI1 SWItching deficient 1314.0 0 0 0 0 -0.5249683355596364 P09547 0.9484469890594482 0.9504740238189696 0.5522790551185608 0.5723895430564879 42.24890973487288 35.0 1.0 no 15163 chrXVI_522134 36941 essential YPL016W 1120 + CCAAATTTTTGCAGAGTCAA silent|CCC>CCG|P|374 silent|CCC>CCT|P|374 SWI1 SWItching deficient 1314.0 0 0 0 0 -0.6006240918842285 P09547 42.07076784640759 35.0 1.0 no 15164 chrXVI_522292 36943 essential YPL016W 1278 + TTACAATCAATACCAGAAAT Q|428|E Q|428|* SWI1 SWItching deficient 1314.0 0 0 0 0 -0.39362078066442696 P09547 0.9590039849281312 0.0426851287484169 -0.2375999987125397 0.1827400028705597 34.30748714459617 25.0 1.0 no 15165 chrXVI_522390r 36944 essential YPL016W 1379 - GGGCCACCATAGACCACTGT A|466|P A|466|T silent|GTG>GTC|V|465 silent|GTG>GTA|V|465 SWI1 SWItching deficient 1314.0 0 0 0 0 -0.12734891673268586 P09547 0.9573720097541808 0.9523990154266356 0.03208720311522484 0.19719833135604856 7.625999927520753 2.500999927520752 10.213879585266113 2.1769399642944336 59.1582585230264 60.0 1.0 no 15166 chrXVI_522410r 36945 essential YPL016W 1399 - ATCGGAAATTTGCAGCCTTT D|473|H D|473|N SWI1 SWItching deficient 1314.0 0 0 0 0 0.1338709469332912 P09547 0.9486550092697144 0.956179976463318 0.04486813768744469 0.2638614177703857 0.6531999707221985 0.6259999871253967 47.21039475917206 40.0 1.0 no 15167 chrXVI_522481 36946 essential YPL016W 1467 + AGACACATGATTTCCCAAGA H|491|D H|491|Y H|491|Q silent|CAC>CAT|H|491 SWI1 SWItching deficient 1314.0 0 0 0 0 0.8468221989955872 P09547 0.9473130106925964 0.9489949941635132 0.9588389992713928 0.009331468492746351 1.0 0.012653897516429424 0.11299999803304672 -0.5752000212669373 -0.5406000018119812 45.43293315556042 40.0 1.0 no 15168 chrXVI_522605r 36948 essential YPL016W 1594 - TGCACTATTAATGTTATTGT A|538|P A|538|T S|537|T S|537|N SWI1 SWItching deficient 1314.0 0 0 0 0 0.6824391299616661 P09547 0.9573720097541808 0.9523990154266356 0.9512869715690612 0.9536849856376648 0.2820035517215729 0.5286228656768799 0.6070342063903809 0.4931716620922089 38.95794047250513 25.0 1.0 no 15169 chrXVI_522627 36949 essential YPL016W 1613 + ATCGTCAGCACCAACCCCCG S|539|W S|539|L S|540|* S|540|L SWI1 SWItching deficient 1314.0 0 0 0 0 0.2785919490937274 P09547 0.9288619756698608 0.9298099875450134 0.9298099875450134 0.02079141512513161 0.3111673593521118 0.3036450147628784 60.238169556437185 65.0 1.0 no 15170 chrXVI_522677 36957 essential YPL016W 1663 + CAGCACCAGGAACAGAAGCA A|556|G A|556|V P|557|A P|557|S SWI1 SWItching deficient 1314.0 0 0 0 0 -0.4466748965506553 P09547 0.9484469890594482 0.9504740238189696 0.9562489986419678 0.9498909711837769 0.381921261548996 0.2917819619178772 0.7302119135856628 0.7428081631660461 49.60941800822451 55.00000000000001 1.0 no 15171 chrXVI_522884 36959 essential YPL016W 1870 + AACTTTTAGAGGATCAACAA L|625|V L|625|F SWI1 SWItching deficient 1314.0 0 0 0 0 -1.0098630720177428 P09547 0.9512209892272948 0.9587849974632264 0.4946507811546326 0.7441947460174559 36.4611945727126 30.0 1.0 no 15172 chrXVI_523248 36964 essential YPL016W 2234 + CCCTGAATTATTAGACTCCT P|746|R P|746|L P|746|A P|746|S SWI1 SWItching deficient 1314.0 0 0 0 0 0.4838656077964122 P09547 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.32061952352523804 0.3768064975738525 0.5635743737220764 0.5616674423217773 47.87688234220809 40.0 1.0 no 15173 chrXVI_523265r 36967 essential YPL016W 2254 - ATTCATGCCGAGTATTGCCA M|757|I M|757|I SWI1 SWItching deficient 1314.0 0 0 0 0 -0.12453668306894712 P09547 0.9553959965705872 0.9553959965705872 1.0 1.0 52.584354603915756 45.0 1.0 no 15174 chrXVI_523382r 36969 essential YPL016W 2371 - ATCAACCATTTTATCGTGTT D|797|H D|797|N V|796|L V|796|I SWI1 SWItching deficient 1314.0 0 0 0 0 0.3238434797905451 P09547 0.9486550092697144 0.956179976463318 0.9539830088615416 0.9574310183525084 0.022916682064533237 0.4297864735126496 1.0 0.5093186497688293 43.3519865177222 30.0 1.0 no 15175 chrXVI_523383r 36970 essential YPL016W 2372 - TATCAACCATTTTATCGTGT D|797|H D|797|N V|796|L V|796|I SWI1 SWItching deficient 1314.0 0 0 0 0 0.34411337520298 P09547 0.9486550092697144 0.956179976463318 0.9539830088615416 0.9574310183525084 0.022916682064533237 0.4297864735126496 1.0 0.5093186497688293 42.55506832347976 30.0 1.0 no 15176 chrXVI_523512r 36972 essential YPL016W 2501 - GCTCCATTTCAGTAGGAGTA E|840|Q E|840|K E|840|D silent|GAG>GAA|E|840 SWI1 SWItching deficient 1314.0 0 0 0 0 1.976964986870166 P09547 0.956179976463318 0.9475290179252625 0.94931298494339 0.5378143787384033 0.7115954160690308 0.7545540928840637 52.08521748345066 45.0 1.0 no 15177 chrXVI_523574 36975 essential YPL016W 2560 + CATCTCCCGCAGTTAAACAG S|855|C S|855|F P|856|A P|856|S SWI1 SWItching deficient 1314.0 0 0 0 0 0.08375683701890277 P09547 0.945252001285553 0.9294660091400146 0.9562489986419678 0.9498909711837769 0.055268965661525726 0.06322462111711502 0.6989058256149292 0.7477965950965881 49.00356925481828 50.0 1.0 no 15178 chrXVI_523575 36976 essential YPL016W 2561 + ATCTCCCGCAGTTAAACAGT S|855|C S|855|F P|856|A P|856|S SWI1 SWItching deficient 1314.0 0 0 0 0 -0.5068630586559311 P09547 0.945252001285553 0.9294660091400146 0.9562489986419678 0.9498909711837769 0.055268965661525726 0.06322462111711502 0.6989058256149292 0.7477965950965881 50.314751890722896 45.0 1.0 no 15179 chrXVI_523709 36978 essential YPL016W 2695 + TTACAAAAATAAATACCAGA T|900|R T|900|I SWI1 SWItching deficient 1314.0 0 0 0 0 0.06937281418621001 P09547 0.9476869702339172 0.9472420215606691 0.0040573813021183005 0.004516875371336937 29.78086039400432 20.0 1.0 no 15180 chrXVI_523772r 36980 essential YPL016W 2761 - ATTCCTCAAAATCATCGAGA R|926|S silent|AGG>AGA|R|926 R|926|T R|926|K SWI1 SWItching deficient 1314.0 0 0 0 0 0.2859900909960845 P09547 0.9087679982185364 0.932735025882721 0.955805003643036 0.0 0.0 0.0 41.07508971926149 35.0 1.0 no 15181 chrXVI_523884r 36981 essential YPL016W 2873 - TGCATGTAAAGTTTTCTGGA C|964|S C|964|Y SWI1 SWItching deficient 1314.0 0 0 0 0 0.5276590451095949 P09547 0.9421560168266296 0.9290120005607604 0.23782528936862946 0.39243239164352417 42.83739545589549 35.0 1.0 no 15182 chrXVI_530017r 36983 essential YPL012W 297 - TTCGATCTTAATAATACCTT silent|TCG>TCC|S|105 silent|TCG>TCA|S|105 R|104|T R|104|K RRP12 Ribosomal RNA Processing 1228.0 0 0 0 1 0.17063387283568274 Q12754 0.020168403163552284 0.6275740265846252 38.012080577886366 25.0 1.0 no 15183 chrXVI_530052r 36984 essential YPL012W 332 - TACATGGGGCAATTTTCGTT C|117|S C|117|Y RRP12 Ribosomal RNA Processing 1228.0 0 0 0 0 0.5709949029262695 Q12754 0.1603570282459259 0.038664255291223526 46.78560283368403 40.0 1.0 no 15184 chrXVI_530067 36985 essential YPL012W 344 + CCCATGTATCACTGCAGAAA P|116|R P|116|L P|116|A P|116|S RRP12 Ribosomal RNA Processing 1228.0 0 0 0 0 0.3382813750423372 Q12754 0.08743440359830856 1.0 0.29812923073768616 0.14056353271007538 47.756639028138245 45.0 1.0 no 15185 chrXVI_530067r 36986 essential YPL012W 347 - CCTTTTCTGCAGTGATACAT K|122|N silent|AAG>AAA|K|122 E|121|Q E|121|K RRP12 Ribosomal RNA Processing 1228.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.1517991765504894 Q12754 0.14812205731868744 0.19838778674602509 0.19611501693725586 48.54372605965108 40.0 1.0 no 15186 chrXVI_530068r 36987 essential YPL012W 348 - GCCTTTTCTGCAGTGATACA K|122|N silent|AAG>AAA|K|122 A|123|P A|123|T RRP12 Ribosomal RNA Processing 1228.0 1 Series([], Name: modification, dtype: object) 0 0 0 -1.3285432226104623 Q12754 0.14812205731868744 0.031016608700156205 0.2520283460617065 52.42826857899513 45.0 1.0 no 15187 chrXVI_530188 36990 essential YPL012W 465 + ACTCCAAAAAGAGGTTTGCA P|157|A P|157|S T|156|S T|156|I RRP12 Ribosomal RNA Processing 1228.0 0 0 0 0 0.2048451523832008 Q12754 0.0 0.0 1.0 0.013918003998696804 43.34995000209813 40.0 1.0 no 15188 chrXVI_530191r 36991 essential YPL012W 471 - ATACCCTGCAAACCTCTTTT G|163|A G|163|D G|163|R G|163|S RRP12 Ribosomal RNA Processing 1228.0 0 0 0 0 -0.523361860045477 Q12754 0.3678283393383026 0.010994181036949158 0.00786360539495945 0.05194169655442238 49.892861825732844 40.0 1.0 no 15189 chrXVI_530289r 36992 essential YPL012W 569 - CTGCAGTTGGTGCAACAGGA A|196|P A|196|T RRP12 Ribosomal RNA Processing 1228.0 0 0 0 0 0.3324404274077741 Q12754 0.30990564823150635 0.6069539785385132 52.846121826077756 55.00000000000001 1.0 no 15190 chrXVI_530509 36995 essential YPL012W 786 + CCTCTTTGTGATGTACTATT L|264|V L|264|F P|263|R P|263|L RRP12 Ribosomal RNA Processing 1228.0 0 0 0 0 0.3472759472673604 Q12754 0.0 0.0 0.5217241048812866 0.2994996011257172 45.92994842353329 35.0 1.0 no 15191 chrXVI_530605 36996 essential YPL012W 882 + GCAGAAACTACCATTTCTTC A|295|G A|295|V RRP12 Ribosomal RNA Processing 1228.0 0 0 0 0 -1.389100452052376 Q12754 0.11519940942525865 0.253142923116684 44.30122730775923 40.0 1.0 no 15192 chrXVI_530693 36997 essential YPL012W 970 + ATACATTATTAACCAAGTCC T|325|R T|325|I RRP12 Ribosomal RNA Processing 1228.0 0 0 0 0 -0.8516709375509035 Q12754 0.496798425912857 0.18087676167488095 39.98619606767943 30.0 1.0 no 15193 chrXVI_530871r 36998 essential YPL012W 1151 - CATCTTTAACAGACTCAGAA D|390|H D|390|N RRP12 Ribosomal RNA Processing 1228.0 0 0 0 0 1.208669342237117 Q12754 0.030413005501031883 0.06863662600517273 39.1641569372627 35.0 1.0 no 15194 chrXVI_531070r 37001 essential YPL012W 1350 - TTCAGTGATTTTAAAAAGTG silent|CTG>CTC|L|456 silent|CTG>CTA|L|456 RRP12 Ribosomal RNA Processing 1228.0 0 0 0 0 0.7864413698516936 Q12754 32.61023967555508 25.0 1.0 no 15195 chrXVI_531186r 37002 essential YPL012W 1466 - CTTCTGCGAGTATCATTTCA E|495|Q E|495|K A|494|P A|494|T RRP12 Ribosomal RNA Processing 1228.0 0 0 0 0 -0.5896099472212142 Q12754 0.025399776175618168 0.03532679751515388 0.22294628620147705 0.4614950716495514 47.45448257902206 40.0 1.0 no 15196 chrXVI_531187r 37003 essential YPL012W 1467 - GCTTCTGCGAGTATCATTTC A|496|P A|496|T E|495|Q E|495|K RRP12 Ribosomal RNA Processing 1228.0 0 0 0 0 -1.3425916601854402 Q12754 0.00976147409528494 0.014805889688432215 0.025399776175618168 0.03532679751515388 50.02396915759016 45.0 1.0 no 15197 chrXVI_531226 37004 essential YPL012W 1503 + AATCCATCTTCCGAAAGACC P|503|A P|503|S P|503|R P|503|L RRP12 Ribosomal RNA Processing 1228.0 0 0 0 0 -0.3952025371866168 Q12754 0.528386116027832 0.5460993051528931 0.501339852809906 0.2263544052839279 46.4844867288241 45.0 1.0 no 15198 chrXVI_531236r 37009 essential YPL012W 1516 - CCAAGCCCTGCCAGGTCTTT W|512|S W|512|* A|511|P A|511|T RRP12 Ribosomal RNA Processing 1228.0 0 0 0 0 -2.114728459129456 Q12754 0.0 0.017724828794598583 0.026131903752684597 62.73803489821113 60.0 1.0 yes 15199 chrXVI_531265r 37010 essential YPL012W 1545 - TTCGTATAATCTCTAATAAG silent|ACG>ACC|T|521 silent|ACG>ACA|T|521 RRP12 Ribosomal RNA Processing 1228.0 0 0 0 0 0.3319480063349243 Q12754 33.42218920797711 25.0 1.0 no 15200 chrXVI_531300 37012 essential YPL012W 1577 + TGCAACTTTTCAAAACGAAT A|527|G A|527|V T|528|S T|528|I RRP12 Ribosomal RNA Processing 1228.0 0 1 0 0 -0.6004147887761873 Q12754 0.7406681776046753 0.14562392234802246 0.2995990812778473 0.4129841923713684 36.044504386906056 30.0 1.0 no 15201 chrXVI_531345 37013 essential YPL012W 1622 + ATCTAAGTTCGATAAAGTCC S|542|C S|542|F RRP12 Ribosomal RNA Processing 1228.0 0 0 0 0 0.3871907680874045 Q12754 0.04878899455070496 0.045929506421089165 40.0978462648921 35.0 1.0 no 15202 chrXVI_531363r 37014 essential YPL012W 1643 - TCAATTGAATAGATTCTTCC L|554|F silent|TTG>TTA|L|554 RRP12 Ribosomal RNA Processing 1228.0 0 0 0 0 0.2577708299532461 Q12754 0.08842596411705017 38.82049618388868 30.0 1.0 no 15203 chrXVI_531364r 37015 essential YPL012W 1644 - CTCAATTGAATAGATTCTTC L|554|F silent|TTG>TTA|L|554 RRP12 Ribosomal RNA Processing 1228.0 0 0 0 0 0.6052883222432196 Q12754 0.08842596411705017 36.66979326320819 30.0 1.0 no 15204 chrXVI_531429 37016 essential YPL012W 1706 + ACGGTTTTGTGAACTCCCAA R|570|G R|570|W RRP12 Ribosomal RNA Processing 1228.0 0 0 0 0 -0.8606284020047976 Q12754 0.5083394646644592 0.1883365511894226 49.23142760741723 45.0 1.0 no 15205 chrXVI_531492 37017 essential YPL012W 1769 + ATCTTCTTTATTATACAGCG S|591|C S|591|F S|592|C S|592|F RRP12 Ribosomal RNA Processing 1228.0 0 1 0 0 0.7266977978031209 Q12754 0.16271165013313293 0.10294906049966812 0.012319992296397686 0.01055139023810625 40.82857539578168 30.0 1.0 no 15206 chrXVI_531528 37018 essential YPL012W 1805 + TACAATTTGTCATGCTTTAA T|603|R T|603|I RRP12 Ribosomal RNA Processing 1228.0 0 0 0 0 1.4799413196488511 Q12754 0.5741738080978394 0.2804082036018372 38.20104778242029 25.0 1.0 no 15207 chrXVI_531623r 37020 essential YPL012W 1903 - ATTCTTTTGAGCTTCAGAAA K|640|N silent|AAG>AAA|K|640 RRP12 Ribosomal RNA Processing 1228.0 0 0 0 0 1.5006019062832219 Q12754 0.14719702303409574 40.501679432663884 30.0 1.0 no 15208 chrXVI_531704 37021 essential YPL012W 1981 + CTCAAACCACTCCAAATGCA Q|662|E Q|662|* T|663|S T|663|I RRP12 Ribosomal RNA Processing 1228.0 0 0 0 0 0.17666472918519746 Q12754 0.2049907147884369 0.07283804565668106 0.15445704758167267 46.0449859050804 45.0 1.0 no 15209 chrXVI_531873 37022 essential YPL012W 2150 + TCAATTGACAGCGACACTAT Q|718|E Q|718|* RRP12 Ribosomal RNA Processing 1228.0 0 1 0 0 0.008472702249931047 Q12754 0.3923570513725281 42.92301642918415 40.0 1.0 no 15210 chrXVI_531963r 37023 essential YPL012W 2243 - CGTCAGCAGAATTTACGGTG D|754|H D|754|N A|753|P A|753|T RRP12 Ribosomal RNA Processing 1228.0 0 0 0 0 -0.808702737066375 Q12754 0.17017017304897308 0.4138930439949036 0.25064191222190857 0.5209233760833739 46.53639036713787 50.0 1.0 no 15211 chrXVI_532021 37024 essential YPL012W 2298 + AAGCTTTCTGAGTTGAAATC L|768|V L|768|F RRP12 Ribosomal RNA Processing 1228.0 0 1 0 0 0.2805111894384151 Q12754 0.02677867002785206 0.025209102779626846 39.67169442780096 35.0 1.0 no 15212 chrXVI_532050 37025 essential YPL012W 2327 + AGCTGTCGCCCAATTCATTT A|777|G A|777|V silent|GTC>GTG|V|778 silent|GTC>GTT|V|778 RRP12 Ribosomal RNA Processing 1228.0 0 0 0 0 -0.5465718178184592 Q12754 0.09164903312921524 0.07526254653930664 53.467713563496254 45.0 1.0 no 15213 chrXVI_532199r 37028 essential YPL012W 2479 - ACTCAAAATAACCTCAGCGA L|832|F silent|TTG>TTA|L|832 S|833|T S|833|N RRP12 Ribosomal RNA Processing 1228.0 0 0 0 0 0.3530560130375576 Q12754 0.1077595129609108 0.19477258622646326 0.08121441304683685 41.995708661089736 40.0 1.0 no 15214 chrXVI_532309 37030 essential YPL012W 2586 + ATCAAATTATTCCAAATACC I|863|M silent|ATC>ATT|I|863 RRP12 Ribosomal RNA Processing 1228.0 0 0 0 0 -0.4994059684358655 Q12754 0.13849185407161713 36.14230181681131 25.0 1.0 no 15215 chrXVI_532384 37032 essential YPL012W 2661 + ATCATTTCTGCCGGTCTTAT I|888|M silent|ATC>ATT|I|888 RRP12 Ribosomal RNA Processing 1228.0 0 0 0 0 0.4196949472329317 Q12754 1.0 51.16035262360845 40.0 1.0 no 15216 chrXVI_534008 37039 essential YPL011C 676 - CATCCTATCTTCGTTTGTTA R|231|S silent|AGG>AGA|R|231 R|231|T R|231|K TAF3 TATA binding protein-Associated Factor 353.0 0 0 0 0 0.9267262967503588 Q12297 0.9087679982185364 0.932735025882721 0.955805003643036 0.483339935541153 0.5641515851020813 0.6678366661071777 47.28100884931917 35.0 0.0 no 15217 chrXVI_534069r 37042 essential YPL011C 612 + CCGGCTTTACCACATATTGC P|205|R P|205|L A|206|G A|206|V TAF3 TATA binding protein-Associated Factor 353.0 0 0 0 0 -1.0118162217359066 Q12297 0.9432820081710817 0.9430609941482544 0.9484469890594482 0.9504740238189696 0.39954328536987305 0.2331656068563461 0.1715470254421234 0.12396468222141264 52.3854137017711 50.0 0.0 no 15218 chrXVI_534314 37043 essential YPL011C 370 - ACTTTGTAGTAATTCTACTG S|130|T S|130|N TAF3 TATA binding protein-Associated Factor 353.0 0 0 0 0 0.7099053098704821 Q12297 0.9512869715690612 0.9536849856376648 0.6650224924087524 0.5084380507469177 38.943574075162296 30.0 0.0 no 15219 chrXVI_534404 37045 essential YPL011C 280 - TCCTCGTGAACTTGATAATT G|100|R G|100|R G|100|A G|100|E TAF3 TATA binding protein-Associated Factor 353.0 0 0 0 0 0.1783771387786253 Q12297 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.0 0.0 0.0 0.0 42.311158226071136 35.0 0.0 no 15220 chrXVI_534405r 37046 essential YPL011C 276 + TCCGAATTATCAAGTTCACG silent|TCC>TCG|S|93 silent|TCC>TCT|S|93 S|93|C S|93|F TAF3 TATA binding protein-Associated Factor 353.0 0 0 0 0 -1.1613214904393756 Q12297 0.945252001285553 0.9294660091400146 0.04051858186721802 0.025474263355135918 42.43528228694481 40.0 0.0 no 15221 chrXVI_534481r 37048 essential YPL011C 200 + ACAAGATATAACTCTGGCTC Q|68|E Q|68|* TAF3 TATA binding protein-Associated Factor 353.0 0 0 0 0 -0.30935784872406724 Q12297 0.9590039849281312 0.0 42.00220184813474 40.0 0.0 no 15222 chrXVI_534593 37050 essential YPL011C 91 - GGTCATGACATCCACCAGAC M|36|I M|36|I TAF3 TATA binding protein-Associated Factor 353.0 0 0 0 0 0.02203074290209818 Q12297 0.9553959965705872 0.9553959965705872 0.9663140177726746 0.9663140177726746 52.9210322769203 55.00000000000001 0.0 no 15223 chrXVI_535102r 37054 essential YPL010W 87 - CCTTCATCAGATCTATGAGG G|36|R G|36|R E|35|Q E|35|K 0 0 0 0 -6.953246158020537 P53600 0.941340982913971 0.941340982913971 0.956179976463318 0.9475290179252625 0.4568721354007721 0.4568721354007721 0.6499531865119934 0.9057961106300354 47.010708256609924 45.0 1.0 yes 15224 chrXVI_535182r 37057 essential YPL010W 167 - AATCTTGCTTGTGAGTCTTA D|62|H D|62|N 0 1 0 0 0.6824723613933941 P53600 0.9486550092697144 0.956179976463318 0.13846969604492188 0.5729839205741882 45.366933136215714 35.0 1.0 no 15225 chrXVI_542695r 37062 essential YPL007C 1131 + ACAATTTCTGAACGTGCTGT T|378|R T|378|I TFC8 Transcription Factor C 588.0 0 0 0 0 0.7350045630979282 Q12308 0.9476869702339172 0.9472420215606691 0.5017552971839905 0.14432886242866516 44.64701492251834 40.0 0.0 no 15226 chrXVI_542718r 37063 essential YPL007C 1108 + TCGCCCCACTATATCATACT A|371|G A|371|V F|370|L silent|TTC>TTT|F|370 TFC8 Transcription Factor C 588.0 0 0 0 0 -0.4791619456393018 Q12308 0.9484469890594482 0.9504740238189696 0.9387490153312684 0.022552501410245892 0.2680582106113434 0.4742575883865357 1.812999963760376 -1.1568000316619873 52.65842899757502 45.0 0.0 no 15227 chrXVI_542790r 37064 essential YPL007C 1036 + CCATAGTATACGATATGGAA silent|GCC>GCG|A|346 silent|GCC>GCT|A|346 TFC8 Transcription Factor C 588.0 0 0 0 0 -1.3332261323543086 Q12308 40.00471244979218 35.0 0.0 no 15228 chrXVI_543013 37066 essential YPL007C 816 - CTCTCTTTCTCATGATTCAA E|278|D silent|GAG>GAA|E|278 E|278|Q E|278|K TFC8 Transcription Factor C 588.0 0 0 0 0 0.43910197731226347 Q12308 0.94931298494339 0.956179976463318 0.9475290179252625 0.550240695476532 0.4196217358112335 0.5223382711410522 44.49641931446854 35.0 0.0 no 15229 chrXVI_543014 37067 essential YPL007C 815 - TCTCTTTCTCATGATTCAAT E|278|Q E|278|K E|278|D silent|GAG>GAA|E|278 TFC8 Transcription Factor C 588.0 0 0 0 0 -0.10053337956858854 Q12308 0.956179976463318 0.9475290179252625 0.94931298494339 0.4196217358112335 0.5223382711410522 0.550240695476532 42.55941653807327 30.0 0.0 no 15230 chrXVI_543096 37069 essential YPL007C 733 - ATCTATCTTATGCACATATC D|251|H D|251|N K|249|N silent|AAG>AAA|K|249 TFC8 Transcription Factor C 588.0 0 0 0 0 0.6035696864785723 Q12308 0.9486550092697144 0.956179976463318 0.9355990290641784 0.049895480275154114 0.9929329752922058 0.0965125486254692 40.918872190093396 30.0 0.0 no 15231 chrXVI_543097 37070 essential YPL007C 732 - TCTATCTTATGCACATATCC D|251|H D|251|N K|249|N silent|AAG>AAA|K|249 TFC8 Transcription Factor C 588.0 0 0 0 0 0.4190777251368252 Q12308 0.9486550092697144 0.956179976463318 0.9355990290641784 0.049895480275154114 0.9929329752922058 0.0965125486254692 44.982315372654114 35.0 0.0 no 15232 chrXVI_543279r 37074 essential YPL007C 547 + ACTGGGTCACTCATATAGTA D|183|E silent|GAC>GAT|D|183 TFC8 Transcription Factor C 588.0 0 0 0 0 -0.07899850159853357 Q12308 0.9532920122146606 1.0 46.75304174284747 40.0 0.0 no 15233 chrXVI_543413r 37075 essential YPL007C 413 + TCCTATTGAATCATCAATCG P|139|R P|139|L P|139|A P|139|S TFC8 Transcription Factor C 588.0 0 0 0 0 -0.3934452507184749 Q12308 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.1581573784351349 0.1402568370103836 0.43471619486808777 0.664720892906189 40.7444396882189 35.0 0.0 no 15234 chrXVI_543544 37077 essential YPL007C 285 - ACGGCCATCCAATCGTCTAT V|102|L V|102|I A|101|P A|101|T TFC8 Transcription Factor C 588.0 0 0 0 0 0.6222985417741365 Q12308 0.9539830088615416 0.9574310183525084 0.9573720097541808 0.9523990154266356 0.05492663383483887 0.3840177059173584 0.0228718314319849 0.02434928901493549 53.08964352880071 50.0 0.0 no 15235 chrXVI_543724 37079 essential YPL007C 105 - GGCTGCCCAATGCTAATATC Q|41|H silent|CAG>CAA|Q|41 silent|GGG>GGC|G|40 silent|GGG>GGA|G|40 TFC8 Transcription Factor C 588.0 0 0 0 0 -0.21114785382608625 Q12308 0.9570760130882264 0.10954801738262177 51.710688972499845 50.0 0.0 no 15236 chrXVI_543730r 37080 essential YPL007C 96 + ACATTTCCTGATATTAGCAT T|33|R T|33|I P|35|A P|35|S TFC8 Transcription Factor C 588.0 0 0 0 0 -0.09816810436188612 Q12308 0.9476869702339172 0.9472420215606691 0.9562489986419678 0.9498909711837769 0.006782710552215576 0.0074068489484488955 0.0 0.0 43.50707918073636 30.0 0.0 no 15237 chrXVI_578717 37088 essential YPR010C 2460 - AAACCAAAATGCTGTGTAAT G|826|A G|826|D G|826|R G|826|S RPA135 RNA Polymerase A 1203.0 0 0 0 0 -7.7707914192926e-05 P22138 0.742914080619812 0.6097995638847351 0.5464754104614258 0.7418310642242432 36.677291079916586 30.0 0.0 no 15238 chrXVI_578847r 37090 essential YPR010C 2327 + CTCGTATACTGGTTATGATA S|777|W S|777|L RPA135 RNA Polymerase A 1203.0 0 0 0 0 -3.488595687708252 P22138 0.0 0.0 42.16236958543538 35.0 0.0 yes 15239 chrXVI_578879 37091 essential YPR010C 2298 - ACAACAGCATTAAACCCGTT V|773|L V|773|I V|772|L V|772|I RPA135 RNA Polymerase A 1203.0 0 0 0 0 -0.03551863867074749 P22138 0.02342613972723484 0.2439977079629898 0.03085346706211567 0.4616611897945404 1.1762000322341921 -0.8622000217437744 45.00534116847525 40.0 0.0 no 15240 chrXVI_578894r 37092 essential YPR010C 2280 + GGCATGGATAACTTTCCAAA silent|GGC>GGG|G|761 silent|GGC>GGT|G|761 RPA135 RNA Polymerase A 1203.0 0 0 0 0 -1.6208802360568288 P22138 44.02789996788721 40.0 0.0 no 15241 chrXVI_578915r 37093 essential YPR010C 2259 + GCTAATTTATATGATGATTA A|754|G A|754|V RPA135 RNA Polymerase A 1203.0 0 0 0 0 -0.0781017965756273 P22138 0.1627500057220459 0.1314428150653839 34.240205401507865 20.0 0.0 no 15242 chrXVI_578965 37094 essential YPR010C 2212 - CAACCTATACAGCTTATTGT R|743|S silent|AGG>AGA|R|743 R|743|T R|743|K RPA135 RNA Polymerase A 1203.0 0 1 0 0 -0.2382934766146429 P22138 0.006040137261152268 0.0077481549233198175 0.11431967467069624 0.36039999127388 -0.4047999978065491 -1.4946000576019287 43.79659836525116 35.0 0.0 no 15243 chrXVI_578973 37096 essential YPR010C 2204 - ACAGCTTATTGTCGGAACGA silent|CTG>CTC|L|741 silent|CTG>CTA|L|741 K|740|N silent|AAG>AAA|K|740 RPA135 RNA Polymerase A 1203.0 0 0 1 Series([], Name: modification, dtype: object) 0 0.8364393346268835 P22138 0.0 46.10744479431224 45.0 0.0 no 15244 chrXVI_579096r 37099 essential YPR010C 2078 + CACAAATATTCTTTCTATTT T|694|R T|694|I RPA135 RNA Polymerase A 1203.0 0 0 0 0 0.48152468044304403 P22138 0.028025379404425618 0.16442428529262546 35.13836392595488 20.0 0.0 no 15245 chrXVI_579179 37100 essential YPR010C 1998 - TTCATGTACACTTGCTCAAA M|672|I M|672|I RPA135 RNA Polymerase A 1203.0 0 0 0 0 0.9668956908640234 P22138 0.03551419824361801 0.03551419824361801 42.75038502845553 35.0 0.0 no 15246 chrXVI_579222r 37103 essential YPR010C 1952 + TCCTGTTCGTTACCTGCCTT P|652|R P|652|L P|652|A P|652|S RPA135 RNA Polymerase A 1203.0 0 0 0 0 0.2245362648902252 P22138 0.0 0.0 0.0 0.0 58.86196495937674 50.0 0.0 no 15247 chrXVI_579252 37104 essential YPR010C 1925 - TCCTAGAATGACCACCAAAT R|648|T R|648|K R|648|S silent|AGG>AGA|R|648 RPA135 RNA Polymerase A 1203.0 0 0 0 0 -0.7712359958053181 P22138 0.0 0.0 0.0 44.44242788351494 40.0 0.0 no 15248 chrXVI_579253r 37105 essential YPR010C 1921 + ACCTATTTGGTGGTCATTCT L|642|V silent|CTA>TTA|L|642 Y|641|* silent|TAC>TAT|Y|641 RPA135 RNA Polymerase A 1203.0 0 0 0 0 0.6139354846590327 P22138 0.027300920337438583 50.882063586063616 40.0 0.0 no 15249 chrXVI_579314 37106 essential YPR010C 1863 - TATCCAATTTCTAGATCAAT G|627|A G|627|E G|627|R G|627|R RPA135 RNA Polymerase A 1203.0 0 0 0 0 -0.008212412144620485 P22138 1.0 0.07810477912425995 0.06138095632195473 0.06138095632195473 38.16976546755916 25.0 0.0 no 15250 chrXVI_579317r 37107 essential YPR010C 1857 + TTACCGATTGATCTAGAAAT P|621|A P|621|S P|621|R P|621|L RPA135 RNA Polymerase A 1203.0 0 1 0 0 -0.8164010633202838 P22138 0.06545861065387726 0.039779923856258385 0.008963556960225105 0.014008925296366216 38.092328588174894 30.0 0.0 no 15251 chrXVI_579364r 37109 essential YPR010C 1810 + TTGCGGATACATTGAGATAT A|605|G A|605|V RPA135 RNA Polymerase A 1203.0 0 0 0 0 0.4119570949691496 P22138 0.048681769520044334 0.913863480091095 41.443239260131115 35.0 0.0 no 15252 chrXVI_579480r 37111 essential YPR010C 1694 + ATACTCACTTGGTGTTGCTC Y|566|* silent|TAC>TAT|Y|566 S|567|* S|567|L RPA135 RNA Polymerase A 1203.0 0 0 0 0 -1.4856714429127056 P22138 0.13773168623447418 -0.2319000065326691 50.414175142647764 45.0 0.0 no 15253 chrXVI_579491r 37112 essential YPR010C 1683 + CCTTCTATATTATACTCACT P|562|R P|562|L S|563|C S|563|F RPA135 RNA Polymerase A 1203.0 0 1 0 0 0.1924958987651375 P22138 0.14791254699230194 0.18978141248226169 0.05049358680844307 0.047153189778327935 2.513400077819824 1.7732000350952148 0.2603999972343445 -0.8773999810218811 42.764390033660455 30.0 0.0 no 15254 chrXVI_579587 37113 essential YPR010C 1590 - GAACCATCTGGTGTATGAAC G|536|A G|536|D G|536|R G|536|S RPA135 RNA Polymerase A 1203.0 0 0 0 0 -3.7550047215176297 P22138 0.0 0.0 0.0 0.0 3.3469998836517334 2.9446001052856445 3.1731998920440674 3.4316000938415527 44.325867192678395 45.0 0.0 yes 15255 chrXVI_579738r 37116 essential YPR010C 1436 + ACAAGTTTCTGGTTATACTG Q|480|E Q|480|* RPA135 RNA Polymerase A 1203.0 0 0 0 0 0.27868202713950524 P22138 0.0 41.56255442485053 35.0 0.0 no 15256 chrXVI_579794r 37117 essential YPR010C 1380 + ATGCAATACTTTTTATCAAC Q|462|E Q|462|* RPA135 RNA Polymerase A 1203.0 0 0 0 0 0.5088098732634236 P22138 1.0 36.256496377596534 25.0 0.0 no 15257 chrXVI_579841r 37118 essential YPR010C 1333 + ACATGTCAAGAGTTTTAATG Y|445|* silent|TAC>TAT|Y|445 S|447|* S|447|L RPA135 RNA Polymerase A 1203.0 0 0 0 0 -2.559005999133385 P22138 0.2731577754020691 36.717505515766675 30.0 0.0 yes 15258 chrXVI_579865 37119 essential YPR010C 1312 - CCTTTTGTCTTTGAAATTAA R|444|T R|444|K RPA135 RNA Polymerase A 1203.0 0 0 0 0 -0.17479982377416275 P22138 0.5770219564437866 0.9292768836021424 38.105529875116304 25.0 0.0 no 15259 chrXVI_580004 37123 essential YPR010C 1173 - TGCGTAGCATCTGGGTTATC silent|ACG>ACC|T|397 silent|ACG>ACA|T|397 RPA135 RNA Polymerase A 1203.0 0 0 0 0 -2.80109348540708 P22138 52.33621643500885 50.0 0.0 yes 15260 chrXVI_580044r 37124 essential YPR010C 1130 + GATCAGAAAGTTGTATTCCT I|378|M silent|ATC>ATT|I|378 RPA135 RNA Polymerase A 1203.0 0 0 0 0 0.19959436497081712 P22138 0.07561247050762178 42.61524630445098 35.0 0.0 no 15261 chrXVI_580110r 37126 essential YPR010C 1064 + TCGCATCGTTCTCGTGCATT silent|CGC>CGG|R|356 silent|CGC>CGT|R|356 R|356|G R|356|C RPA135 RNA Polymerase A 1203.0 0 0 0 0 0.6410883457370274 P22138 0.05507348105311394 0.0067953309044241905 54.07368548872358 50.0 0.0 no 15262 chrXVI_580151 37129 essential YPR010C 1026 - ACTTCTAAATCAGATTGATC V|349|L V|349|I E|348|Q E|348|K RPA135 RNA Polymerase A 1203.0 0 0 0 0 -1.2313583803778672 P22138 0.04993150755763054 0.292563796043396 0.3557193875312805 0.22029387950897214 36.855090458777 30.0 0.0 no 15263 chrXVI_580153 37130 essential YPR010C 1024 - TTCTAAATCAGATTGATCAG E|348|Q E|348|K RPA135 RNA Polymerase A 1203.0 0 0 0 0 -1.8332546084998933 P22138 0.3557193875312805 0.22029387950897214 36.0029079484678 30.0 0.0 no 15264 chrXVI_580267 37132 essential YPR010C 910 - TAACAGTAATTCTAAACGAT silent|CTG>CTC|L|309 silent|CTG>CTA|L|309 RPA135 RNA Polymerase A 1203.0 0 0 0 0 -0.5023051075605218 P22138 32.86720032964274 25.0 0.0 no 15265 chrXVI_580276 37133 essential YPR010C 901 - TTCTAAACGATCGGTCAAAA E|307|Q E|307|K RPA135 RNA Polymerase A 1203.0 0 0 0 0 0.410638927042116 P22138 0.014810087159276009 0.013029422610998155 0.2768000066280365 0.12620000541210175 37.424750632262366 35.0 0.0 no 15266 chrXVI_580327 37134 essential YPR010C 850 - ATCAAAAATTTCCCTATCGC D|290|H D|290|N RPA135 RNA Polymerase A 1203.0 0 0 0 0 -0.1151762167082888 P22138 0.016117449849843982 0.2124689519405365 1.5381999015808103 -0.34599998593330383 42.03212695014457 35.0 0.0 no 15267 chrXVI_580339r 37136 essential YPR010C 835 + CCTTGTGTCATACCAGCGAT silent|GCC>GCG|A|279 silent|GCC>GCT|A|279 RPA135 RNA Polymerase A 1203.0 0 0 0 0 1.463566602881347 P22138 53.53565034833115 50.0 0.0 no 15268 chrXVI_580361 37137 essential YPR010C 816 - GCTTTTAAAATCATAACAAC A|279|P A|279|T RPA135 RNA Polymerase A 1203.0 0 0 0 0 -0.13773672840898565 P22138 0.014050576835870745 0.011846599169075487 32.41296966444298 25.0 0.0 no 15269 chrXVI_580100r 37138 essential YPR010C 1074 + CTCGTGCATTTGGGTAAGGA silent|CTC>CTG|L|359 silent|CTC>CTT|L|359 H|361|D H|361|Y RPA135 RNA Polymerase A 1203.0 0 0 0 0 -0.16603460498098815 P22138 0.0 0.0 50.18495989512826 50.0 0.0 no 15270 chrXVI_580522r 37141 essential YPR010C 652 + TCAGACCTTCCTTCGCTAAC I|218|M silent|ATC>ATT|I|218 P|220|A P|220|S RPA135 RNA Polymerase A 1203.0 0 0 0 0 0.5809821688326167 P22138 0.1165098398923874 0.13675673305988312 0.4033860862255096 52.00162807850438 50.0 0.0 no 15271 chrXVI_580744 37143 essential YPR010C 433 - GTTCTCCTCGCCATTGTTCA E|150|D silent|GAG>GAA|E|150 E|150|Q E|150|K RPA135 RNA Polymerase A 1203.0 0 0 0 0 0.2777873826937861 P22138 0.58522629737854 0.5713098645210266 0.9211382269859314 58.40091938289237 50.0 0.0 no 15272 chrXVI_580809 37144 essential YPR010C 368 - GCCTTTGTCTTGACTCACTT R|129|T R|129|K R|129|S silent|AGG>AGA|R|129 RPA135 RNA Polymerase A 1203.0 0 0 0 0 -0.5316015321502623 P22138 0.14649182558059692 0.07673299312591553 0.15228837728500366 1.3056999444961548 0.464000016450882 1.2985000610351562 53.47997444470684 45.0 0.0 no 15273 chrXVI_580905 37146 essential YPR010C 272 - TAACAGAAAGCTTATTCCCG V|97|L V|97|I RPA135 RNA Polymerase A 1203.0 0 0 0 0 0.6146982614737322 P22138 0.8773232102394104 1.0 -0.3109999895095825 0.074066661298275 42.7305661617865 40.0 0.0 no 15274 chrXVI_581033r 37152 essential YPR010C 141 + TCTTTTAACGCATTAACAGA S|48|C S|48|F RPA135 RNA Polymerase A 1203.0 0 0 0 0 1.4085815476491614 P22138 0.004195406567305327 0.0017479887465015054 38.89209872737274 30.0 0.0 no 15275 chrXVI_581056r 37154 essential YPR010C 118 + AAGCTGTTCAACCTCATATT A|41|G A|41|V RPA135 RNA Polymerase A 1203.0 0 0 0 0 0.055983710165135925 P22138 0.019925152882933617 0.6145332455635071 44.89470745440627 35.0 0.0 no 15276 chrXVI_581122 37155 essential YPR010C 55 - GAACCTAGATTCACGTTCTA R|24|S silent|AGG>AGA|R|24 R|24|T R|24|K RPA135 RNA Polymerase A 1203.0 0 0 0 0 0.3091628583710121 P22138 45.002394152691686 40.0 0.0 no 15277 chrXVI_592593r 37160 essential YPR016C 454 + GTTCTTTAAGTAATCAAGGT S|153|C S|153|F TIF6 Translation Initiation Factor 245.0 0 0 0 0 -0.2410100144525804 Q12522 0.08133240044116974 0.0530453659594059 0.3014400005340576 19.49795913696289 39.269608144606025 30.0 0.0 no 15278 chrXVI_592626 37161 essential YPR016C 424 - AACTAAGATATTACCTGATA V|148|L V|148|I TIF6 Translation Initiation Factor 245.0 0 0 0 0 0.5755003218471828 Q12522 0.013852057047188282 0.08390065282583238 1.954439997673035 0.9326000213623048 35.51933809206872 25.0 0.0 no 15279 chrXVI_592639r 37162 essential YPR016C 408 + GTCTTCCGTCAAACCATATC silent|GTC>GTG|V|137 silent|GTC>GTT|V|137 F|138|L silent|TTC>TTT|F|138 TIF6 Translation Initiation Factor 245.0 0 0 0 0 0.3822494850178785 Q12522 0.022598914802074432 1.5297000408172607 1.297320008277893 48.59965946454196 45.0 0.0 no 15280 chrXVI_592740 37163 essential YPR016C 310 - ACAACAGATGACGTTACCCA C|110|S C|110|Y C|109|S C|109|Y TIF6 Translation Initiation Factor 245.0 0 0 0 0 -2.4561964528107865 Q12522 0.06855393946170807 0.0017717296723276375 0.33329781889915466 0.015441155061125757 1.4388600587844849 21.154380798339844 1.1465200185775757 7.4909400939941415 46.85453457332119 45.0 0.0 yes 15281 chrXVI_592776 37164 essential YPR016C 274 - CTCTACCCTTTGAATCTTAA E|98|Q E|98|K V|97|L V|97|I TIF6 Translation Initiation Factor 245.0 0 0 0 0 0.5059131175429542 Q12522 0.10847347974777223 0.039790473878383636 0.25350898504257197 1.0 0.15884000062942505 0.029920000582933426 0.034919999539852135 0.5533000230789185 44.44047596579611 35.0 0.0 no 15282 chrXVI_592831 37165 essential YPR016C 219 - TCTTGATCAGTAGTTTGGGT E|80|Q E|80|K TIF6 Translation Initiation Factor 245.0 0 0 0 0 -2.2767764263729666 Q12522 0.0 0.0 3.1080598831176762 3.405659914016724 48.711260927404105 40.0 0.0 yes 15283 chrXVI_592906r 37168 essential YPR016C 141 + ATCGTTCATACCACTATTGC I|48|M silent|ATC>ATT|I|48 H|50|D H|50|Y TIF6 Translation Initiation Factor 245.0 0 0 0 0 0.16450418855944424 Q12522 0.01167973130941391 0.2488899827003479 0.2857440412044525 -1.3314199447631836 0.9477000236511229 -0.5855399966239929 -0.4577600061893463 47.185706175887844 40.0 0.0 no 15284 chrXVI_592984r 37172 essential YPR016C 63 + ACTTACTGTTTGGTTGCTGT T|22|S T|22|I Y|23|* silent|TAC>TAT|Y|23 TIF6 Translation Initiation Factor 245.0 0 0 0 0 -0.8694841879058159 Q12522 0.8061435222625732 0.05452694743871689 0.2795200049877167 -0.8357999920845032 50.11801858963668 40.0 0.0 no 15285 chrXVI_596905r 37178 essential YPR019W 158 - CCTCTCCCTGACTTAAGTTC E|59|Q E|59|K E|59|D silent|GAG>GAA|E|59 MCM4 MiniChromosome Maintenance 933.0 0 1 0 0 -0.4590059351237442 P30665 1.021209955215454 0.9918810129165648 1.0002800226211548 0.5899530053138733 0.9199238419532776 0.619763195514679 53.87830638775654 50.0 1.0 no 15286 chrXVI_596979r 37179 essential YPR019W 232 - AACATCGGAATTTTGTCTTT V|84|L V|84|I D|83|H D|83|N MCM4 MiniChromosome Maintenance 933.0 0 1 0 0 -0.3496115462858541 P30665 1.0158300399780271 1.0197000503540041 0.9798099994659424 1.0220500230789185 0.6821274161338806 0.5725152492523193 0.11987251043319702 0.5176336765289307 40.49399157748786 30.0 1.0 no 15287 chrXVI_596993 37181 essential YPR019W 243 + TCCGATGTTTTCCAATCTCA silent|TCC>TCG|S|82 silent|TCC>TCT|S|82 S|82|C S|82|F MCM4 MiniChromosome Maintenance 933.0 0 0 1 Series([], Name: modification, dtype: object) 0 0.4393627959731802 P30665 0.853302001953125 0.8562710285186768 0.05158442258834839 0.048972487449646 49.421501224369365 40.0 1.0 no 15288 chrXVI_597098 37184 essential YPR019W 348 + CCTACTTCTTCCTCTTCTTT P|117|R P|117|L T|118|S T|118|I MCM4 MiniChromosome Maintenance 933.0 0 1 0 0 0.6751698708056754 P30665 0.9652510285377502 0.97224098443985 1.0119700431823728 0.9774580001831056 0.5819645524024963 0.4668565690517426 0.8977828621864319 0.4908564984798432 53.57110392225285 40.0 1.0 no 15289 chrXVI_597107 37185 essential YPR019W 357 + TCCTCTTCTTTAGGCCGTAA silent|TCC>TCG|S|120 silent|TCC>TCT|S|120 S|120|C S|120|F MCM4 MiniChromosome Maintenance 933.0 0 0 0 1 0.6306879316317939 P30665 0.8545929789543152 0.851980984210968 0.05173097923398018 0.034989923238754266 53.4302581433215 45.0 1.0 no 15290 chrXVI_597185r 37187 essential YPR019W 438 - TCAAAATCCACAATTCTTCT D|153|H D|153|N MCM4 MiniChromosome Maintenance 933.0 0 0 0 0 0.4559459578590641 P30665 0.8596540093421936 1.0222699642181396 0.12612439692020416 0.4848718345165253 39.73072124021371 30.0 1.0 no 15291 chrXVI_597241 37188 essential YPR019W 491 + TTCTTCTTCTGCTCCTCCAT S|165|C S|165|F S|166|C S|166|F MCM4 MiniChromosome Maintenance 933.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.4500108073485467 P30665 0.8462010025978088 0.9361860156059264 0.8541250228881836 0.9644880294799804 0.08364134281873703 0.21967735886573792 0.19447220861911774 0.7161173820495605 57.6322853889713 45.0 1.0 no 15292 chrXVI_597639 37192 essential YPR019W 889 + AGACCAAGTTTTATAAAGTA T|298|S T|298|I silent|ACC>ACG|T|298 silent|ACC>ACT|T|298 MCM4 MiniChromosome Maintenance 933.0 0 0 0 0 0.4379465275522062 P30665 1.0115100145339966 1.0054199695587158 0.7634457945823669 0.19690975546836853 35.98025189519285 25.0 1.0 no 15293 chrXVI_597662r 37193 essential YPR019W 915 - TTACAAGAACCTACATTGTA C|311|S C|311|Y MCM4 MiniChromosome Maintenance 933.0 0 0 0 0 -0.13332343930319865 P30665 1.007140040397644 0.9419699907302856 0.4520479738712311 0.1550951898097992 38.69756147478381 30.0 1.0 no 15294 chrXVI_597665 37194 essential YPR019W 915 + TACAATGTAGGTTCTTGTAA Y|306|* silent|TAC>TAT|Y|306 MCM4 MiniChromosome Maintenance 933.0 0 0 0 0 -0.7579740153654326 P30665 39.4362912243551 30.0 1.0 no 15295 chrXVI_597757 37196 essential YPR019W 1007 + TCCGGTTATCCCTGATATGA P|337|R P|337|L P|337|A P|337|S MCM4 MiniChromosome Maintenance 933.0 0 0 0 0 -0.4349020702965979 P30665 0.9618989825248718 0.9445800185203552 1.021209955215454 1.0133099555969238 0.005154793616384268 0.006969974376261234 0.19179806113243106 0.0739988386631012 51.970278210926104 45.0 1.0 no 15296 chrXVI_597796 37199 essential YPR019W 1046 + CAACGTCTGCGATCATACAA N|350|K silent|AAC>AAT|N|350 silent|GTC>GTG|V|351 silent|GTC>GTT|V|351 MCM4 MiniChromosome Maintenance 933.0 0 0 0 0 0.3114265215353696 P30665 0.9972079992294312 0.8840665221214294 44.12219029750685 45.0 1.0 no 15297 chrXVI_597851r 37200 essential YPR019W 1104 - TCAATACGTTCACACCTAGC D|375|H D|375|N R|373|P R|373|H MCM4 MiniChromosome Maintenance 933.0 0 0 0 0 -0.12553908715308915 P30665 1.0780500173568726 1.1248699426651 0.8210960030555725 0.9724169969558716 0.1364237517118454 0.4945900142192841 0.013699052855372429 0.014491493813693525 47.18675253155277 45.0 1.0 no 15298 chrXVI_597852r 37201 essential YPR019W 1105 - ATCAATACGTTCACACCTAG D|375|H D|375|N MCM4 MiniChromosome Maintenance 933.0 0 0 0 0 1.1028944320865721 P30665 1.0780500173568726 1.1248699426651 0.1364237517118454 0.4945900142192841 43.60908925117667 40.0 1.0 no 15299 chrXVI_597891 37202 essential YPR019W 1141 + CCATGTCACTGATTCACAAC silent|TCC>TCG|S|381 silent|TCC>TCT|S|381 S|383|* S|383|L MCM4 MiniChromosome Maintenance 933.0 0 0 0 0 -0.8405785545134151 P30665 0.9900929927825928 0.34367266297340393 45.88456479420847 45.0 1.0 no 15300 chrXVI_597891r 37203 essential YPR019W 1144 - CCTGTTGTGAATCAGTGACA R|388|T R|388|K MCM4 MiniChromosome Maintenance 933.0 0 0 0 0 -0.37352330132949385 P30665 0.8481820225715637 0.97849702835083 0.004513608291745186 0.02773698978126049 47.78002693215427 45.0 1.0 no 15301 chrXVI_597956r 37205 essential YPR019W 1209 - TGTCCATCAGGCACAAAGTC G|409|A G|409|E G|409|R G|409|R MCM4 MiniChromosome Maintenance 933.0 0 0 0 0 0.7516949640793894 P30665 0.8484129905700684 0.8262789845466614 0.8217059969902039 0.8217059969902039 0.0 0.0 0.0 0.0 50.02630000246188 50.0 1.0 no 15302 chrXVI_598075r 37208 essential YPR019W 1328 - GCCTGGAATTAGCTCTAATG R|449|T R|449|K R|449|S silent|AGG>AGA|R|449 MCM4 MiniChromosome Maintenance 933.0 0 1 0 0 0.8176723604571402 P30665 1.0750099420547483 1.1060500144958496 1.0372500419616701 0.00998526718467474 0.09992028772830963 0.007903379388153553 46.538239745383464 45.0 1.0 no 15303 chrXVI_598077r 37209 essential YPR019W 1330 - TTGCCTGGAATTAGCTCTAA R|449|S silent|AGG>AGA|R|449 R|449|T R|449|K MCM4 MiniChromosome Maintenance 933.0 0 1 0 0 -0.017559286425890577 P30665 1.0372500419616701 1.0750099420547483 1.1060500144958496 0.007903379388153553 0.00998526718467474 0.09992028772830963 46.80834675904161 40.0 1.0 no 15304 chrXVI_598195 37211 essential YPR019W 1445 + ACAAGAATTAATGCAGAACA Q|483|E Q|483|* MCM4 MiniChromosome Maintenance 933.0 0 0 0 0 -3.7932206173107086 P30665 1.0115599632263184 1.0 34.77479432273606 30.0 1.0 yes 15305 chrXVI_598329r 37214 essential YPR019W 1582 - TTCTAGCTCGTAAATACTTG E|534|Q E|534|K E|532|D silent|GAG>GAA|E|532 MCM4 MiniChromosome Maintenance 933.0 0 0 0 0 -1.1031558913091586 P30665 0.9697070121765136 0.9597989916801452 0.9503329992294312 0.016763290390372276 0.013101545162498951 0.1830345094203949 40.40812057376604 35.0 1.0 no 15306 chrXVI_598330r 37215 essential YPR019W 1583 - CTTCTAGCTCGTAAATACTT E|534|Q E|534|K MCM4 MiniChromosome Maintenance 933.0 0 0 0 0 0.16756778131711458 P30665 0.9697070121765136 0.9597989916801452 0.016763290390372276 0.013101545162498951 42.20306612672345 35.0 1.0 no 15307 chrXVI_598331r 37216 essential YPR019W 1584 - TCTTCTAGCTCGTAAATACT D|535|H D|535|N E|534|Q E|534|K MCM4 MiniChromosome Maintenance 933.0 0 0 0 0 -0.9614407340015216 P30665 0.816743016242981 0.9130499958992004 0.9697070121765136 0.9597989916801452 0.0 0.0 0.016763290390372276 0.013101545162498951 42.89890363094611 35.0 1.0 no 15308 chrXVI_598390 37218 essential YPR019W 1640 + CACGAATAAAACCTTTACCA T|548|R T|548|M MCM4 MiniChromosome Maintenance 933.0 0 0 0 0 0.7701516691962605 P30665 0.953025996685028 0.8842530250549316 0.002413621172308922 0.0014542058343067765 39.38926208891928 35.0 1.0 no 15309 chrXVI_598407r 37220 essential YPR019W 1660 - ACCTCTATAACGGCCACCCT G|560|R G|560|S G|560|A G|560|D MCM4 MiniChromosome Maintenance 933.0 0 0 0 0 -2.0633808950511425 P30665 0.7679520249366759 0.9503960013389589 0.9137219786643982 0.7885500192642212 0.0 0.0 0.0 0.0 57.08479009299799 55.00000000000001 1.0 yes 15310 chrXVI_598431 37221 essential YPR019W 1681 + ACATAAATATTTTACTTTGT D|561|E silent|GAC>GAT|D|561 MCM4 MiniChromosome Maintenance 933.0 0 0 0 0 0.6278515420045098 P30665 1.0083800554275513 0.18775402009487152 32.5797304090188 15.0 1.0 no 15311 chrXVI_598505r 37225 essential YPR019W 1758 - CCCGAAGTATACACACCACG silent|TCG>TCC|S|592 silent|TCG>TCA|S|592 G|593|R G|593|S MCM4 MiniChromosome Maintenance 933.0 0 0 0 0 -1.7707778680857702 P30665 0.8301259875297546 0.8486710190773009 0.0 0.0 49.394932130580905 55.00000000000001 1.0 no 15312 chrXVI_598576 37226 essential YPR019W 1826 + CGACACAAAACAACTTGTTT D|610|E silent|GAC>GAT|D|610 T|611|R T|611|I MCM4 MiniChromosome Maintenance 933.0 0 0 0 0 0.7107485956773689 P30665 0.9751560091972352 0.7777209877967834 0.7988110184669495 1.0 0.0037086473312228922 0.004246096592396498 37.37197110475944 35.0 1.0 no 15313 chrXVI_598583 37227 essential YPR019W 1833 + AAACAACTTGTTTTGGAAAG Q|613|E Q|613|* L|614|V L|614|F MCM4 MiniChromosome Maintenance 933.0 0 0 0 0 0.7157852975288399 P30665 1.0194799900054932 0.95906400680542 1.0168499946594238 0.08085763454437256 0.0811641588807106 0.012213822454214096 33.86181176642674 30.0 1.0 no 15314 chrXVI_598607 37228 essential YPR019W 1857 + GCATTAGTATTGTCTGATGG A|620|G A|620|V MCM4 MiniChromosome Maintenance 933.0 0 0 0 0 0.2657230694838316 P30665 0.8530790209770203 0.8791750073432922 0.0 0.0 45.134148365835706 40.0 1.0 no 15315 chrXVI_598706 37229 essential YPR019W 1956 + ACTATTTCAATCGCAAAAGC T|653|S T|653|I MCM4 MiniChromosome Maintenance 933.0 0 0 0 0 0.9502982977238316 P30665 0.9548959732055664 0.8620949983596802 0.032969377934932716 0.003176394617184997 39.018589294839614 35.0 1.0 no 15316 chrXVI_613675 37234 essential YPR025C 864 - TCCTGGCTACCTTCTCTGCT Q|294|H silent|CAG>CAA|Q|294 E|295|Q E|295|K CCL1 393.0 0 1 0 0 0.6093443208938247 P37366 0.09748487174510956 0.3648662865161896 0.4213980734348297 61.49243349561669 55.00000000000001 0.0 no 15317 chrXVI_613707 37236 essential YPR025C 832 - TTCTAAATACCTTGTGACCA E|284|Q E|284|K CCL1 393.0 0 0 0 0 -0.7073926451045913 P37366 0.3935093283653259 0.5543186664581299 43.8652873895515 35.0 0.0 no 15318 chrXVI_613820 37237 essential YPR025C 719 - TCTTACACCTATCGTATATT K|246|N silent|AAG>AAA|K|246 C|245|S C|245|Y CCL1 393.0 0 0 0 0 1.1036703542855684 P37366 0.01972688548266888 0.29010024666786194 0.008277105167508125 42.92768675741644 30.0 0.0 no 15319 chrXVI_613862 37239 essential YPR025C 677 - CCTTACCATAAAGGACGTTC K|232|N silent|AAG>AAA|K|232 G|231|A G|231|D CCL1 393.0 0 0 0 0 -0.0991892672648847 P37366 0.03136231005191803 0.4301564395427704 0.7869085669517517 45.63737377078326 45.0 0.0 no 15320 chrXVI_613900r 37242 essential YPR025C 636 + CATCCTTACAAACCGCTTCA P|214|A P|214|S P|214|R P|214|L CCL1 393.0 0 0 0 0 0.20080629293067606 P37366 0.4773884415626526 0.2438952028751373 0.0446772463619709 0.055423371493816376 48.77127142453446 45.0 0.0 no 15321 chrXVI_614039r 37244 essential YPR025C 497 + TATCTTTCTAGCCTGCAAAT I|167|M silent|ATC>ATT|I|167 CCL1 393.0 0 0 0 0 0.4763539913750225 P37366 0.017562776803970337 45.52840051114885 35.0 0.0 no 15322 chrXVI_614219 37248 essential YPR025C 320 - GTTCTTCTTCCATTGTCAAA E|113|Q E|113|K E|112|Q E|112|K CCL1 393.0 0 0 0 0 0.3816262024117413 P37366 0.11581885069608687 0.01824004203081131 0.10822067409753801 0.01799103617668152 46.385739962409964 35.0 0.0 no 15323 chrXVI_614385r 37251 essential YPR025C 151 + ACTCTTCTCAGTATAGAATG S|52|C S|52|F H|51|Q silent|CAC>CAT|H|51 CCL1 393.0 0 0 0 0 0.6967769879203041 P37366 0.0 0.0 0.27210691571235657 40.609545147549966 35.0 0.0 no 15324 chrXVI_614484 37252 essential YPR025C 55 - CTCTTTTTCTTTTGCTGACA E|25|Q E|25|K CCL1 393.0 0 0 0 0 0.8273796864628497 P37366 47.05629480759404 35.0 0.0 no 15325 chrXVI_623762 37253 no_effect YPR028W 102 + CCTAAATCTTATTTAGTTGC P|35|R P|35|L YOP1 YIP One Partner 180.0 0 0 0 0 0.7235884710028869 Q12402 0.9432820081710817 0.9430609941482544 0.0 0.0 40.235737753697435 30.0 1.0 no 15326 chrXVI_623768 37255 no_effect YPR028W 108 + TCTTATTTAGTTGCTGGTTT S|37|C S|37|F YOP1 YIP One Partner 180.0 0 0 0 0 0.6984598859297357 Q12402 0.945252001285553 0.9294660091400146 0.08100946992635727 0.04073188453912735 45.54241920666043 30.0 1.0 no 15327 chrXVI_623847r 37256 no_effect YPR028W 190 - CAACACAAACCCAGCAAAAT silent|GTG>GTC|V|69 silent|GTG>GTA|V|69 V|69|L V|69|M YOP1 YIP One Partner 180.0 0 0 0 0 0.05630278338435112 Q12402 0.9539830088615416 0.9587630033493042 0.4123769104480744 0.1215042844414711 40.258445214522624 40.0 1.0 no 15328 chrXVI_623913r 37258 no_effect YPR028W 256 - GGTCAAGAGTTGTGTGTCAT L|91|F silent|TTG>TTA|L|91 YOP1 YIP One Partner 180.0 0 0 0 0 -0.12549561439607132 Q12402 0.9587849974632264 0.0 49.42018514178675 45.0 1.0 no 15329 chrXVI_623919 37259 no_effect YPR028W 259 + ACACACAACTCTTGACCTAC T|88|R T|88|I D|87|E silent|GAC>GAT|D|87 YOP1 YIP One Partner 180.0 0 0 0 0 0.2414081954542497 Q12402 0.9476869702339172 0.9472420215606691 0.9532920122146606 0.004690301604568957 0.006647163070738316 0.0 45.49901002993283 45.0 1.0 no 15330 chrXVI_623979r 37260 no_effect YPR028W 322 - AATCAAATATAGAATTGCCT L|113|F silent|TTG>TTA|L|113 YOP1 YIP One Partner 180.0 0 0 0 0 0.2125785653783872 Q12402 0.9587849974632264 0.0952514037489891 35.915313872021216 25.0 1.0 no 15331 chrXVI_624038 37261 no_effect YPR028W 378 + TACATTGCCTTGCCTCAAAC Y|127|* silent|TAC>TAT|Y|127 YOP1 YIP One Partner 180.0 0 0 0 0 0.9683678878219244 Q12402 49.03620943488386 45.0 1.0 no 15332 chrXVI_624050r 37263 no_effect YPR028W 393 - ATTCTAGCGCCACCAGTTTG R|137|T R|137|K YOP1 YIP One Partner 180.0 0 0 0 0 0.01850887603182991 Q12402 0.932735025882721 0.955805003643036 0.4082217216491699 0.6698583960533142 54.12684588204127 50.0 1.0 no 15333 chrXVI_637824r 37264 essential YPR033C 1173 + TCTACTCAAATTCCATGTGT S|392|C S|392|F T|393|S T|393|I HTS1 Histidine-Trna Synthetase 546.0 0 0 0 0 -0.10020633861887597 P07263 0.945252001285553 0.9294660091400146 0.9491789937019348 0.9472420215606691 0.01570008508861065 0.009285461157560349 0.3881211280822754 0.10468003898859024 0.3892000019550324 -0.4955999851226807 -0.7160000205039978 -0.3343999981880188 44.42135062135208 35.0 0.0 no 15334 chrXVI_637854r 37265 essential YPR033C 1143 + AACATGTTCTCTGAAGCTTC N|382|K silent|AAC>AAT|N|382 HTS1 Histidine-Trna Synthetase 546.0 0 0 0 0 0.6506075684677293 P07263 0.9439849853515624 0.0549197643995285 44.29096707399458 40.0 0.0 no 15335 chrXVI_637962 37267 essential YPR033C 1038 - TTCAATTCTGAAGCATTCTC L|352|F silent|TTG>TTA|L|352 HTS1 Histidine-Trna Synthetase 546.0 0 0 0 0 -0.0715494131976499 P07263 0.9587849974632264 0.055200111120939255 -0.23739999532699585 41.982469846037134 35.0 0.0 no 15336 chrXVI_638137r 37269 essential YPR033C 860 + CAACATTACTTCAAACGAAA N|288|K silent|AAC>AAT|N|288 HTS1 Histidine-Trna Synthetase 546.0 0 0 0 0 0.06383041912995235 P07263 0.9439849853515624 0.9441479444503784 33.83691395890645 30.0 0.0 no 15337 chrXVI_638268 37270 essential YPR033C 732 - TCCTTCTTGACTGCTTCCCA K|250|N silent|AAG>AAA|K|250 E|251|Q E|251|K HTS1 Histidine-Trna Synthetase 546.0 0 0 0 0 -1.248749435654391 P07263 0.9355990290641784 0.956179976463318 0.9475290179252625 0.06758683919906616 0.0 0.0 58.644132832020425 50.0 0.0 no 15338 chrXVI_638299r 37272 essential YPR033C 698 + CTCTTCTGCTGTCGATAAGT S|234|C S|234|F S|235|C S|235|F HTS1 Histidine-Trna Synthetase 546.0 0 0 0 0 0.4236782084481525 P07263 0.945252001285553 0.9294660091400146 0.945252001285553 0.9294660091400146 0.38009989261627203 0.03938407823443413 0.0019089385168626907 0.0007683620206080378 49.03471937748218 45.0 0.0 no 15339 chrXVI_638381r 37276 essential YPR033C 616 + TCAAAATCAAATTGAATCAC F|206|L silent|TTC>TTT|F|206 HTS1 Histidine-Trna Synthetase 546.0 0 0 0 0 0.8443033348093303 P07263 0.9387490153312684 0.03095835261046886 3.8350000381469727 30.553816579580943 25.0 0.0 no 15340 chrXVI_638435 37277 essential YPR033C 565 - CACTAAAATGGACAAACATT V|195|L V|195|M HTS1 Histidine-Trna Synthetase 546.0 0 0 0 0 -0.357204733640536 P07263 0.9539830088615416 0.9587630033493042 0.6296131014823914 0.21386969089508054 33.58756640627206 30.0 0.0 no 15341 chrXVI_638778r 37287 essential YPR033C 219 + GCCATTTTTAGCACTTTATC silent|GCC>GCG|A|74 silent|GCC>GCT|A|74 A|74|G A|74|V HTS1 Histidine-Trna Synthetase 546.0 0 0 0 1 -0.3511901465855445 P07263 0.9484469890594482 0.9504740238189696 0.3858048617839813 0.2593640387058258 1.1124000549316406 0.11339999735355374 46.85513880547832 35.0 0.0 no 15342 chrXVI_639554 37290 essential YPR034W 29 + ACATAACGGATCGCACAGAA H|11|D H|11|Y N|12|K silent|AAC>AAT|N|12 ARP7 Actin-Related Protein 477.0 0 0 0 0 -0.7638100010478267 Q12406 0.4055815935134888 0.09611231088638306 0.21716617047786715 0.31578001379966736 -0.28835999965667725 4.822100162506104 43.05363267443744 45.0 1.0 no 15343 chrXVI_639618r 37292 essential YPR034W 96 - GTTCTTTTAATATAGCTAGA R|38|T R|38|K ARP7 Actin-Related Protein 477.0 0 1 0 0 -2.6753459209544497 Q12406 0.4302486777305603 1.0 0.5577399730682373 1.6981199979782104 38.27433392901179 25.0 1.0 yes 15344 chrXVI_639676r 37293 essential YPR034W 154 - CGCAGCGTCTATCATATTGT A|58|P A|58|T A|57|P A|57|T ARP7 Actin-Related Protein 477.0 0 0 0 0 -1.3534201111244837 Q12406 0.2275935113430023 0.3369329273700714 0.2501358091831207 0.5037702322006226 10.444439888000488 2.882960081100464 2.1427600383758545 4.010819911956787 7.767600059509277 2.7411999702453613 3.6085999011993413 1.098399996757507 49.66304201606915 45.0 1.0 no 15345 chrXVI_639743r 37298 essential YPR034W 221 - CCCAATTGTACGGTAACCCT W|80|S W|80|* W|80|C W|80|* ARP7 Actin-Related Protein 477.0 0 0 0 0 -3.329622747065649 Q12406 0.0 0.0 3.9850800037384033 4.268620014190674 52.45730308415914 50.0 1.0 yes 15346 chrXVI_639753r 37300 essential YPR034W 231 - TCCAATGCGTCCCAATTGTA L|83|F silent|TTG>TTA|L|83 E|84|Q E|84|K ARP7 Actin-Related Protein 477.0 0 0 0 0 -1.2713224166123702 Q12406 0.02359587140381336 0.06753627955913544 0.15629276633262634 6.134900093078612 -0.1199600026011467 -0.7227200269699097 51.40863571017582 45.0 1.0 no 15347 chrXVI_639802r 37301 essential YPR034W 280 - CTCGGGTGAAACTTTCAATT E|100|Q E|100|K ARP7 Actin-Related Protein 477.0 0 0 0 0 0.0561684772754938 Q12406 0.4353465437889099 0.6499876976013184 -0.3830400109291077 -0.3226799964904785 42.66605320740115 40.0 1.0 no 15348 chrXVI_639819r 37304 essential YPR034W 297 - ATCACCAGTGGCAGTTCCTC silent|GTG>GTC|V|105 silent|GTG>GTA|V|105 V|105|L V|105|M ARP7 Actin-Related Protein 477.0 0 0 0 0 -0.1832360174466881 Q12406 0.3461100161075592 0.02904657647013664 -0.6665599942207336 0.5596399903297424 58.55507018242599 55.00000000000001 1.0 no 15349 chrXVI_639820r 37305 essential YPR034W 298 - AATCACCAGTGGCAGTTCCT silent|GTG>GTC|V|105 silent|GTG>GTA|V|105 V|105|L V|105|M ARP7 Actin-Related Protein 477.0 0 0 0 0 -2.856002404618665 Q12406 0.3461100161075592 0.02904657647013664 -0.6665599942207336 0.5596399903297424 55.32880971756424 50.0 1.0 yes 15350 chrXVI_639848 37307 essential YPR034W 323 + GCCTGCCACCAATGGTAAAC P|109|R P|109|L P|109|A P|109|S ARP7 Actin-Related Protein 477.0 0 0 0 0 -0.4717999354503329 Q12406 0.02122308686375618 0.01837626472115517 0.21947380900383 0.05768850818276405 3.2302000522613525 1.690400004386902 2.273900032043457 2.2524399757385254 52.420345163875474 55.00000000000001 1.0 no 15351 chrXVI_639877r 37310 essential YPR034W 355 - CTCATAGTAGCGCTCTAATA E|125|Q E|125|K ARP7 Actin-Related Protein 477.0 0 0 0 0 0.27520791834154673 Q12406 0.09925894439220427 0.3608166575431824 -0.6665400266647339 -1.1100200414657593 45.42217427285533 40.0 1.0 no 15352 chrXVI_639924r 37311 essential YPR034W 402 - TCGATTACAATCTGGAATAC E|141|Q E|141|K ARP7 Actin-Related Protein 477.0 0 0 0 0 -3.643016854687168 Q12406 0.06874173879623413 0.06856836378574371 -0.20559999346733093 -1.2064199447631836 37.75605681063092 35.0 1.0 yes 15353 chrXVI_639932r 37312 essential YPR034W 410 - CCAATGGCTCGATTACAATC L|143|F silent|TTG>TTA|L|143 ARP7 Actin-Related Protein 477.0 0 0 0 0 -1.4295876358174615 Q12406 0.02473950013518333 -0.06818000227212906 8.437199592590332 45.02910775905508 45.0 1.0 no 15354 chrXVI_639932 37313 essential YPR034W 407 + CCAGATTGTAATCGAGCCAT Q|137|E Q|137|* ARP7 Actin-Related Protein 477.0 0 0 0 0 -0.44531811459087134 Q12406 0.18791519105434415 0.6212999820709229 48.42899527136075 45.0 1.0 no 15355 chrXVI_640017 37315 essential YPR034W 492 + AACGTTACTCCCATCATTGA N|165|K silent|AAC>AAT|N|165 ARP7 Actin-Related Protein 477.0 0 0 0 0 0.4047163682998765 Q12406 0.5253890752792358 0.3349199891090393 47.46787969710681 40.0 1.0 no 15356 chrXVI_640026r 37316 essential YPR034W 504 - ACCACAATACCGTCAATGAT silent|GTG>GTC|V|174 silent|GTG>GTA|V|174 V|175|L V|175|M ARP7 Actin-Related Protein 477.0 0 0 0 0 -0.3131932228135529 Q12406 0.5239028930664062 0.029011500999331474 -0.7815200090408325 -0.7472400069236755 -2.280800104141236 -1.5606000423431396 44.52986810788707 40.0 1.0 no 15357 chrXVI_640304 37319 essential YPR034W 779 + ACAGGAGCAGTTAAAACAAA Q|261|E Q|261|* ARP7 Actin-Related Protein 477.0 0 0 0 0 -1.5044078650452417 Q12406 0.2756600081920624 36.77297905514803 35.0 1.0 no 15358 chrXVI_640415 37322 essential YPR034W 890 + GACTTTAACCTTGGACCTTA T|298|S T|298|I ARP7 Actin-Related Protein 477.0 0 0 0 0 0.2035349822620288 Q12406 0.0 0.0 0.3760400116443634 -0.7353600263595581 46.86237951964205 40.0 1.0 no 15359 chrXVI_640481 37323 essential YPR034W 956 + ATCAGACAAATTCTCACCAG S|320|* S|320|L D|321|E silent|GAC>GAT|D|321 ARP7 Actin-Related Protein 477.0 0 0 0 0 -1.297760026131325 Q12406 0.2330679297447205 1.0 -1.0253599882125854 -0.0154600003734231 42.56557710004603 40.0 1.0 no 15360 chrXVI_640497r 37327 essential YPR034W 975 - AGCGGTCCCAGTCCGTCCTC silent|CCG>CCC|P|331 silent|CCG>CCA|P|331 G|330|A G|330|E ARP7 Actin-Related Protein 477.0 0 0 0 0 -2.773518929463512 Q12406 0.1712963879108429 0.03666435554623604 2.0421800613403316 5.703859806060791 68.0303045641815 70.0 1.0 yes 15361 chrXVI_640578 37330 essential YPR034W 1053 + TCCACCAACCCAAACGGATT silent|TCC>TCG|S|352 silent|TCC>TCT|S|352 S|352|C S|352|F ARP7 Actin-Related Protein 477.0 0 0 0 0 0.1819223997389587 Q12406 0.05536455288529396 0.0547141507267952 50.35239944942679 50.0 1.0 no 15362 chrXVI_640586r 37331 essential YPR034W 1064 - GGCTTGTACCCAATCCGTTT S|361|T S|361|N ARP7 Actin-Related Protein 477.0 0 0 0 0 -0.5407859962433628 Q12406 0.02879999950528145 0.14820000529289246 55.84899197715663 50.0 1.0 no 15363 chrXVI_640587r 37332 essential YPR034W 1065 - TGGCTTGTACCCAATCCGTT S|361|T S|361|N ARP7 Actin-Related Protein 477.0 0 0 0 0 -1.1462244157317478 Q12406 0.02879999950528145 0.14820000529289246 55.50931675065482 50.0 1.0 no 15364 chrXVI_642264r 37334 essential YPR035W 59 - CGGCAATTATTCTACCTCTT A|26|P A|26|T GLN1 GLutamiNe metabolism 370.0 0 0 0 0 -0.7193455432167264 P32288 0.9573720097541808 0.9523990154266356 0.04343423619866371 0.14527633786201474 2.4251599311828613 2.0276200771331787 3.3795199394226074 1.6111400127410889 47.587460965390854 40.0 1.0 no 15365 chrXVI_642283 37336 essential YPR035W 75 + GCCGAATACGTTTGGATCGA silent|GCC>GCG|A|26 silent|GCC>GCT|A|26 A|26|G A|26|V GLN1 GLutamiNe metabolism 370.0 0 0 0 0 -0.06160360940315138 P32288 0.9484469890594482 0.9504740238189696 0.00788891687989235 0.8072402477264404 2.0813000202178955 -0.7657399773597717 1.8756999969482424 0.445360004901886 48.382839549850864 50.0 1.0 no 15366 chrXVI_642356 37337 essential YPR035W 148 + CCATTGACCAATTGCCAGAA silent|TCC>TCG|S|50 silent|TCC>TCT|S|50 GLN1 GLutamiNe metabolism 370.0 0 0 0 0 1.2137374933649008 P32288 48.33302792394557 45.0 1.0 no 15367 chrXVI_642370r 37341 essential YPR035W 165 - GAACCGTCGAAGTTCCATTC G|61|A G|61|D G|61|R G|61|S GLN1 GLutamiNe metabolism 370.0 0 0 0 0 -3.175520482635203 P32288 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.048527657985687256 0.004517414141446352 0.0016520313220098615 0.00893951766192913 1.8575199842453003 12.385740280151367 15.007019996643065 6.681399822235107 48.82462973294719 50.0 1.0 yes 15368 chrXVI_642494r 37345 essential YPR035W 289 - ACCGTCATTGTTGTAACATG G|103|R G|103|S G|103|A G|103|D GLN1 GLutamiNe metabolism 370.0 0 0 0 0 -0.947143612839414 P32288 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.8330943584442139 0.1436416357755661 0.17551666498184204 0.0556214340031147 3.173180103302002 3.4173400402069087 3.2724199295043945 3.3265600204467773 44.792905044509546 40.0 1.0 no 15369 chrXVI_642619 37347 essential YPR035W 411 + GACATGTATGACGATGTTTA D|138|E silent|GAC>GAT|D|138 GLN1 GLutamiNe metabolism 370.0 0 0 0 0 0.016391955348816458 P32288 0.9532920122146606 0.19532717764377594 0.7094799876213074 40.759850258618776 35.0 1.0 no 15370 chrXVI_642667 37349 essential YPR035W 459 + CCACAAGGTCCTTACTACTG Q|155|E Q|155|* P|154|R P|154|L GLN1 GLutamiNe metabolism 370.0 0 0 0 0 0.2072284064571824 P32288 0.9590039849281312 0.9432820081710817 0.9430609941482544 0.005018353927880526 0.0030849119648337364 0.004826549906283617 -0.06041999906301498 0.003000000026077032 0.3510400056838989 0.15716999769210815 0.7006299495697021 49.85250333507986 50.0 1.0 no 15371 chrXVI_642796 37354 essential YPR035W 588 + TCTCAATGGGAATTCCAAGT Q|198|E Q|198|* S|197|C S|197|F GLN1 GLutamiNe metabolism 370.0 0 0 0 0 -1.1636253318578893 P32288 0.9590039849281312 0.945252001285553 0.9294660091400146 0.0030285785906016827 0.004010347183793783 0.0015129175735637546 3.30679988861084 2.0005199909210205 26.76453971862793 44.731762726843435 40.0 1.0 no 15372 chrXVI_642820 37355 essential YPR035W 612 + CCATGTACCGGTATTGACAT P|205|R P|205|L GLN1 GLutamiNe metabolism 370.0 0 0 0 0 -0.3713752181511252 P32288 0.9432820081710817 0.9430609941482544 0.006293727084994315 0.0384892076253891 1.6108399629592896 1.6191600561141968 49.210687578986146 45.0 1.0 no 15373 chrXVI_642820r 37356 essential YPR035W 615 - CCCATGTCAATACCGGTACA M|211|I M|211|I G|212|R G|212|S GLN1 GLutamiNe metabolism 370.0 0 0 0 0 -0.9997708464836084 P32288 0.9553959965705872 0.9553959965705872 0.941340982913971 0.951104998588562 0.5309723615646362 0.5309723615646362 0.0019159669755026696 0.04855741187930107 2.7421998977661133 2.7421998977661133 22.30944061279297 5.771039962768555 52.0017315393514 50.0 1.0 no 15374 chrXVI_642909 37358 essential YPR035W 701 + ATTCCATCCAAAGCCATTGA F|235|L silent|TTC>TTT|F|235 H|236|D H|236|Y GLN1 GLutamiNe metabolism 370.0 0 1 0 0 -0.9849174391634776 P32288 0.9387490153312684 0.9473130106925964 0.9489949941635132 0.6023240685462952 1.0 0.034651923924684525 0.99481999874115 -0.302619993686676 0.08885999768972397 0.324180006980896 -0.09025999903678894 0.04376000165939331 48.76251898453403 40.0 1.0 no 15375 chrXVI_642922r 37360 essential YPR035W 717 - CCGTTCCAGTCACCCTTCAA G|246|R G|246|S W|244|C W|244|* GLN1 GLutamiNe metabolism 370.0 0 0 0 0 -2.3804961825549067 P32288 0.941340982913971 0.951104998588562 0.8858469724655151 0.0014056921936571598 0.010107035748660564 0.019351255148649216 6.923659801483153 4.266019821166991 2.8383998870849614 2.833120107650757 58.48550364726543 55.00000000000001 1.0 yes 15376 chrXVI_642954 37361 essential YPR035W 746 + TCACACTAACGTTTCCACCA H|250|Q silent|CAC>CAT|H|250 H|250|D H|250|Y GLN1 GLutamiNe metabolism 370.0 0 0 0 0 -1.4426421421453797 P32288 0.9588389992713928 0.9473130106925964 0.9489949941635132 0.0023430932778865103 0.00556813133880496 0.0014709391398355365 0.4432199895381928 2.556940078735352 -1.0738199949264526 49.649653723888896 45.0 1.0 no 15377 chrXVI_642988r 37363 essential YPR035W 783 - TCGATGTATTTCATACCACC E|268|Q E|268|K GLN1 GLutamiNe metabolism 370.0 0 0 0 0 -1.2256608151026451 P32288 0.956179976463318 0.9475290179252625 0.2309350222349167 0.3678009510040283 -0.5658199787139893 -0.4105400145053864 46.709236525874864 40.0 1.0 no 15378 chrXVI_643016r 37364 essential YPR035W 811 - TCTCTTGGATAACTTCTCGA K|276|N silent|AAG>AAA|K|276 R|277|T R|277|K GLN1 GLutamiNe metabolism 370.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.34144944722790205 P32288 0.9355990290641784 0.932735025882721 0.955805003643036 0.42473843693733215 0.40003901720047 0.7461837530136108 0.7832000255584717 0.7977200150489807 1.0799599885940552 45.38332049088446 40.0 1.0 no 15379 chrXVI_643042 37365 essential YPR035W 834 + GCTGAACACATTAAGTTGTA A|279|G A|279|V H|281|D H|281|Y GLN1 GLutamiNe metabolism 370.0 0 1 0 0 1.559019322127968 P32288 0.9484469890594482 0.9504740238189696 0.9473130106925964 0.9489949941635132 0.3771954476833344 0.29107654094696045 0.17442815005779266 0.01089146826416254 0.4568000137805938 0.4722799956798554 3.5406200885772705 6.0290398597717285 0.741100013256073 0.1011200025677681 40.885311217296355 35.0 1.0 no 15380 chrXVI_643882 37366 high_effect YPR036W 46 + TCCGTAGTATAATCCGTTCG R|17|G R|17|C I|16|M silent|ATC>ATT|I|16 VMA13 Vacuolar Membrane Atpase 478.0 0 0 0 0 -0.7240961961449973 P41807 0.8994590044021606 0.8926740288734436 0.9598389863967896 0.016706058755517006 0.002274557715281844 0.13180001080036166 2.353600025177002 1.0908000469207764 -0.916800022125244 -0.9710000157356262 48.05709055567718 45.0 1.0 no 15381 chrXVI_643883r 37367 high_effect YPR036W 50 - ACCTCGAACGGATTATACTA R|23|T R|23|K R|23|S silent|AGG>AGA|R|23 VMA13 Vacuolar Membrane Atpase 478.0 0 1 0 0 -0.4137316149543548 P41807 0.932735025882721 0.955805003643036 0.9087679982185364 0.015595157630741596 0.2567501664161682 0.01249197218567133 0.5360000133514404 -0.11980000138282774 0.5645999908447266 43.48708925897632 40.0 1.0 no 15382 chrXVI_644019 37373 high_effect YPR036W 183 + TCTTCGAACAATGCACATTC S|62|C S|62|F S|63|W S|63|L VMA13 Vacuolar Membrane Atpase 478.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.7712472694730852 P41807 0.945252001285553 0.9294660091400146 0.9288619756698608 0.9298099875450134 0.06715810298919678 0.11554405838251115 0.020492002367973328 0.13132815062999725 0.08240000158548355 -0.004999999888241291 -0.052400000393390656 0.02160000056028366 42.47811136446154 40.0 1.0 no 15383 chrXVI_644020 37374 high_effect YPR036W 184 + CTTCGAACAATGCACATTCC S|63|W S|63|L VMA13 Vacuolar Membrane Atpase 478.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.903319492178192 P41807 0.9288619756698608 0.9298099875450134 0.020492002367973328 0.13132815062999725 -0.052400000393390656 0.02160000056028366 45.19458401569409 45.0 1.0 no 15384 chrXVI_644089r 37375 high_effect YPR036W 256 - GCAGTCTTCGTTGTCTGAGG C|92|S C|92|Y D|91|H D|91|N VMA13 Vacuolar Membrane Atpase 478.0 0 1 0 0 -0.6468661524622208 P41807 0.9421560168266296 0.9290120005607604 0.9486550092697144 0.956179976463318 0.056717399507760995 0.022000687196850777 0.0 0.0 1.4628000259399414 13.102800369262695 0.15279999375343326 -0.1356000006198883 -0.8342000246047974 8.607199668884277 54.8118489219915 55.00000000000001 1.0 no 15385 chrXVI_644129r 37376 high_effect YPR036W 296 - ACGATAACAATTCAGCTATT silent|TCG>TCC|S|105 silent|TCG>TCA|S|105 VMA13 Vacuolar Membrane Atpase 478.0 0 0 0 0 0.20968978806730626 P41807 38.43210568127262 30.0 1.0 no 15386 chrXVI_644242 37379 high_effect YPR036W 406 + TCCAGACTGTGCTAATCTCT Q|137|E Q|137|* F|136|L silent|TTC>TTT|F|136 VMA13 Vacuolar Membrane Atpase 478.0 0 0 0 0 -1.4181135103693727 P41807 0.9590039849281312 0.9387490153312684 0.4000225365161896 0.1809237599372864 2.212399959564209 -0.40939998626708973 0.1136000007390976 50.697637143791894 45.0 1.0 no 15387 chrXVI_644416r 37383 high_effect YPR036W 583 - GTCACGATACTCTGGTATCA D|201|H D|201|N R|200|P R|200|H VMA13 Vacuolar Membrane Atpase 478.0 0 0 0 0 -0.3123867548767509 P41807 0.9486550092697144 0.956179976463318 0.9099509716033936 0.9570810198783876 0.12650182843208313 0.491948276758194 0.011036011390388012 0.012184752151370049 0.061000000685453415 0.4410000145435333 13.957200050354006 8.551400184631348 48.2608100078217 45.0 1.0 no 15388 chrXVI_644473r 37386 high_effect YPR036W 640 - ACGTTGCAGGATCTTGAATA R|220|P R|220|H silent|CTG>CTC|L|218 silent|CTG>CTA|L|218 VMA13 Vacuolar Membrane Atpase 478.0 0 0 0 0 0.7029475051095448 P41807 0.9099509716033936 0.9570810198783876 0.34820464253425604 0.3373725414276123 1.1282000541687012 -0.5012000203132629 44.50102147638995 40.0 1.0 no 15389 chrXVI_644492 37387 high_effect YPR036W 656 + ACGTGCCACGGACTCTCAAT R|220|G R|220|C A|221|G A|221|V VMA13 Vacuolar Membrane Atpase 478.0 0 0 0 0 -0.06640486518604607 P41807 0.8994590044021606 0.8926740288734436 0.9484469890594482 0.9504740238189696 0.5424556136131287 0.12412688136100768 0.24649325013160706 0.6952502727508545 0.3736000061035156 0.22360000014305115 1.3619999885559082 1.2591999769210815 1.3730000257492063 0.7233999967575073 52.77449336557135 55.00000000000001 1.0 no 15390 chrXVI_644528 37388 high_effect YPR036W 692 + TGCAACAAACTCCAACCACC A|232|G A|232|V T|233|R T|233|I VMA13 Vacuolar Membrane Atpase 478.0 0 0 0 0 1.0133004422393588 P41807 0.9484469890594482 0.9504740238189696 0.9476869702339172 0.9472420215606691 0.11779999732971193 1.8251999616622925 47.70579869483834 50.0 1.0 no 15391 chrXVI_644543r 37389 high_effect YPR036W 710 - ACTGCAATTGAATACCCAGG Q|243|H silent|CAG>CAA|Q|243 L|242|F silent|TTG>TTA|L|242 VMA13 Vacuolar Membrane Atpase 478.0 0 0 0 0 -1.8980145004503948 P41807 0.9570760130882264 0.9587849974632264 0.014374728314578531 0.21772173047065732 1.4206000566482544 2.284600019454956 46.09696821577842 45.0 1.0 no 15392 chrXVI_644645 37392 high_effect YPR036W 809 + TTTCTTGGACCTCTTGAAAT F|271|L silent|TTC>TTT|F|271 VMA13 Vacuolar Membrane Atpase 478.0 0 0 0 0 0.17120634859377645 P41807 0.9387490153312684 1.0 2.0357999801635738 43.755354926231966 35.0 1.0 no 15393 chrXVI_644677r 37393 high_effect YPR036W 844 - TCTGGACACTTTCTCCTTTA R|288|T R|288|K silent|GTG>GTC|V|286 silent|GTG>GTA|V|286 VMA13 Vacuolar Membrane Atpase 478.0 0 0 0 0 0.20168534134847294 P41807 0.932735025882721 0.955805003643036 0.0 0.0 0.8471999764442444 -0.186599999666214 49.87591828417095 40.0 1.0 no 15394 chrXVI_644827r 37398 high_effect YPR036W 994 - GTCTTGACGCAATTCTTCGT D|338|H D|338|N VMA13 Vacuolar Membrane Atpase 478.0 0 0 0 0 0.8983263376983797 P41807 0.9486550092697144 0.956179976463318 0.0 0.0 -0.5203999876976013 -0.3704000115394592 49.18705502065609 45.0 1.0 no 15395 chrXVI_644870r 37399 high_effect YPR036W 1037 - ATTCTTGGTACTCGTTTTCT E|352|Q E|352|K VMA13 Vacuolar Membrane Atpase 478.0 0 0 0 0 -0.2858681188517529 P41807 0.956179976463318 0.9475290179252625 0.2923734486103058 0.40347960591316223 -0.3003999888896942 -0.4991999864578247 47.72967450833573 35.0 1.0 no 15396 chrXVI_644899r 37400 high_effect YPR036W 1066 - TTCGGCGACGTATTCATCGA E|362|Q E|362|K A|361|P A|361|T VMA13 Vacuolar Membrane Atpase 478.0 0 0 0 0 -0.5082223916870059 P41807 0.956179976463318 0.9475290179252625 0.9573720097541808 0.9523990154266356 0.0 0.0 0.2460608929395676 0.4464055597782135 -0.3492000102996826 0.4356000125408173 3.2669999599456787 2.6010000705718994 5.402200222015381 0.19020000100135806 49.39293051313098 50.0 1.0 no 15397 chrXVI_648757 37403 essential YPR041W 53 + GCCTCCCATCCAAGCCAAGG P|19|R P|19|L P|19|A P|19|S TIF5 Translation Initiation Factor 405.0 0 0 0 0 -2.0962577437015892 P38431 0.04215676710009575 0.031088354066014286 0.13648399710655212 0.07596955448389052 61.57519195705987 65.0 1.0 yes 15398 chrXVI_648758r 37405 essential YPR041W 57 - TCCACCTTGGCTTGGATGGG silent|GTG>GTC|V|25 silent|GTG>GTA|V|25 E|26|Q E|26|K TIF5 Translation Initiation Factor 405.0 0 0 0 0 -2.1323996424607157 P38431 0.0 0.0 58.1055032288545 60.0 1.0 yes 15399 chrXVI_648762r 37406 essential YPR041W 61 - ACCTTCCACCTTGGCTTGGA G|27|R G|27|S G|27|A G|27|D TIF5 Translation Initiation Factor 405.0 0 1 0 0 -1.0396775041419728 P38431 0.0 0.0 0.0 0.0 59.599607506346274 55.00000000000001 1.0 no 15400 chrXVI_648761r 37407 essential YPR041W 60 - CCTTCCACCTTGGCTTGGAT G|27|R G|27|S E|26|Q E|26|K TIF5 Translation Initiation Factor 405.0 0 1 0 0 -1.8358036672954947 P38431 0.0 0.0 0.0 0.0 59.08829181694341 55.00000000000001 1.0 no 15401 chrXVI_648766r 37408 essential YPR041W 65 - CTCTACCTTCCACCTTGGCT R|28|T R|28|K G|27|A G|27|D TIF5 Translation Initiation Factor 405.0 0 1 0 0 -1.6217920962627606 P38431 0.01236928254365921 1.0 0.0 0.0 60.114410974850905 55.00000000000001 1.0 no 15402 chrXVI_648854 37409 essential YPR041W 150 + CCATATATTGTCAAGTATTT P|51|R P|51|L TIF5 Translation Initiation Factor 405.0 0 0 0 0 0.6257096417812225 P38431 0.08885235339403152 0.17203913629055026 39.284701609988254 25.0 1.0 no 15403 chrXVI_649038r 37411 essential YPR041W 337 - TCGAACCAAATCATTATCTT R|119|P R|119|Q V|118|L V|118|I TIF5 Translation Initiation Factor 405.0 0 0 0 0 0.2744538160793761 P38431 0.062487207353115075 0.1044820323586464 0.7387613654136658 0.4987627565860748 39.21179026876507 30.0 1.0 no 15404 chrXVI_649143r 37414 essential YPR041W 442 - CTTCTTCTTGGAACCAGAAA K|153|N silent|AAG>AAA|K|153 K|152|N silent|AAG>AAA|K|152 TIF5 Translation Initiation Factor 405.0 0 0 0 0 0.455192139355127 P38431 0.5697216391563416 0.06834886968135834 43.39126178711661 40.0 1.0 no 15405 chrXVI_649178 37415 essential YPR041W 474 + ACCGCTTCGGCCAATGTTCG silent|ACC>ACG|T|159 silent|ACC>ACT|T|159 T|159|S T|159|I TIF5 Translation Initiation Factor 405.0 0 0 1 Series([], Name: modification, dtype: object) 0 -0.5602377137093872 P38431 0.7206014394760132 0.1837351769208908 56.06176301320903 60.0 1.0 no 15406 chrXVI_649188r 37418 essential YPR041W 487 - CAACCCACCACCACGAACAT silent|GGG>GGC|G|168 silent|GGG>GGA|G|168 G|168|A G|168|E TIF5 Translation Initiation Factor 405.0 0 0 0 0 -0.6097994708556057 P38431 0.5710961222648621 0.9138420224189758 51.47991099951275 55.00000000000001 1.0 no 15407 chrXVI_649238 37419 essential YPR041W 534 + TCTCAGAATGCACCTTCAGA Q|180|E Q|180|* S|179|C S|179|F TIF5 Translation Initiation Factor 405.0 0 1 0 0 -0.9754142720986966 P38431 1.0 0.04052551835775376 0.039066031575202935 49.06473764224819 45.0 1.0 no 15408 chrXVI_649277r 37420 essential YPR041W 576 - TCGTCTTCGTCATGATGTTG E|199|Q E|199|K D|198|H D|198|N TIF5 Translation Initiation Factor 405.0 0 1 0 0 0.8445573167991054 P38431 0.15930451452732086 0.14548157155513766 0.08493093401193619 0.5326823592185974 48.15908847694653 45.0 1.0 no 15409 chrXVI_649332r 37422 essential YPR041W 631 - CTCGATATCTTCTAAGGTAG E|217|Q E|217|K TIF5 Translation Initiation Factor 405.0 0 1 0 0 -1.669357746535907 P38431 0.5001637935638428 0.8038965463638306 42.11294932712656 40.0 1.0 no 15410 chrXVI_649443 37426 essential YPR041W 739 + AACTGGATGAATATGGTGAA L|248|V silent|CTG>TTG|L|248 TIF5 Translation Initiation Factor 405.0 0 1 0 0 -0.4070958856344938 P38431 0.05897625908255578 2.2309200763702397 2.075360059738159 37.732932246698 35.0 1.0 no 15411 chrXVI_649555 37428 essential YPR041W 851 + TCCAAAAATTGGTTGTGTCT P|285|R P|285|L P|285|A P|285|S TIF5 Translation Initiation Factor 405.0 0 0 0 0 0.7802732651585909 P38431 0.30670687556266785 0.518450915813446 0.4586280286312103 0.5650798082351685 2.288379907608032 1.6613800525665283 1.7866599559783936 3.08951997756958 42.60649767988463 35.0 1.0 no 15412 chrXVI_659255 37431 essential YPR048W 73 + TATCCCATCGACTACATCGC S|26|C S|26|F silent|TCC>TCG|S|26 silent|TCC>TCT|S|26 TAH18 Top1T722A mutant Hypersensitive 623.0 0 0 0 0 0.15438784315792153 Q12181 0.945252001285553 0.9294660091400146 0.043455753475427635 0.020767461508512497 51.00170460087828 50.0 1.0 no 15413 chrXVI_659285r 37433 essential YPR048W 106 - ACCAATGGAGCAAAATGTAT G|42|R G|42|S G|42|A G|42|D TAH18 Top1T722A mutant Hypersensitive 623.0 0 0 0 0 0.6784215897687552 Q12181 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.02098819613456726 0.07899873703718185 0.03003502823412418 1.0 39.794455754106885 35.0 1.0 no 15414 chrXVI_659316r 37434 essential YPR048W 137 - TGCATTTCAAGATATCCTGT C|52|S C|52|Y TAH18 Top1T722A mutant Hypersensitive 623.0 0 0 0 0 -0.5219124380797722 Q12181 0.9421560168266296 0.9290120005607604 0.40276223421096796 1.0 45.365542863763544 35.0 1.0 no 15415 chrXVI_659547 37436 essential YPR048W 365 + TCAGCGCATTGTCACACAAT Q|123|E Q|123|* R|124|G R|124|C TAH18 Top1T722A mutant Hypersensitive 623.0 0 0 0 0 -1.7409651556094787 Q12181 0.9590039849281312 0.8994590044021606 0.8926740288734436 0.7825806736946106 0.0 0.0 48.42027068766038 45.0 1.0 no 15416 chrXVI_659548 37437 essential YPR048W 366 + CAGCGCATTGTCACACAATT R|124|G R|124|C silent|CGC>CGG|R|124 silent|CGC>CGT|R|124 TAH18 Top1T722A mutant Hypersensitive 623.0 0 0 0 0 -3.134920285528511 Q12181 0.8994590044021606 0.8926740288734436 0.0 0.0 47.65914998563386 45.0 1.0 yes 15417 chrXVI_659682r 37441 essential YPR048W 503 - ACTTACTTAAAAGAAAGCTT K|174|N silent|AAG>AAA|K|174 S|173|T S|173|N TAH18 Top1T722A mutant Hypersensitive 623.0 0 0 0 0 0.04112619560763078 Q12181 0.9355990290641784 0.9512869715690612 0.9536849856376648 0.5570205450057983 0.4503185749053955 0.3230525851249695 33.48730224328051 25.0 1.0 no 15418 chrXVI_659727r 37443 essential YPR048W 548 - ATTCTTCCCTCTTAATTATT E|189|Q E|189|K E|188|Q E|188|K TAH18 Top1T722A mutant Hypersensitive 623.0 0 0 0 0 0.4618369185124282 Q12181 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.4545377492904663 0.6949614882469177 0.5787720680236816 0.7084586620330809 43.97388986502767 25.0 1.0 no 15419 chrXVI_659824 37446 essential YPR048W 642 + AGCACCAAGGTTATATTCGA S|215|R silent|AGC>AGT|S|215 T|216|S T|216|I TAH18 Top1T722A mutant Hypersensitive 623.0 0 0 0 0 0.3907545997995168 Q12181 0.9417110085487366 0.9491789937019348 0.9472420215606691 0.5433457493782043 0.6568877100944519 0.4973336160182953 46.110380246924755 40.0 1.0 no 15420 chrXVI_659910r 37449 essential YPR048W 731 - ACTTGAACTGCCTCACGTCT K|250|N silent|AAG>AAA|K|250 TAH18 Top1T722A mutant Hypersensitive 623.0 0 0 0 0 0.06289882300269048 Q12181 0.9355990290641784 0.3705950677394867 52.18555480686166 50.0 1.0 no 15421 chrXVI_659984r 37452 essential YPR048W 805 - ATCTGTATTGCAAGGATATA D|275|H D|275|N TAH18 Top1T722A mutant Hypersensitive 623.0 0 0 0 0 0.13097074217182658 Q12181 0.9486550092697144 0.956179976463318 0.5296090245246887 0.5938506722450256 40.13883581472209 30.0 1.0 no 15422 chrXVI_659992r 37453 essential YPR048W 813 - ACATCCTCATCTGTATTGCA V|278|L V|278|I D|277|H D|277|N TAH18 Top1T722A mutant Hypersensitive 623.0 0 0 0 0 0.06305306778831726 Q12181 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 0.0 0.0 0.013183477334678171 0.030944043770432476 50.158260493064574 40.0 1.0 no 15423 chrXVI_660023 37454 essential YPR048W 841 + TCCTAGCAAATCAAAGCCAT L|282|V silent|CTA>TTA|L|282 F|281|L silent|TTC>TTT|F|281 TAH18 Top1T722A mutant Hypersensitive 623.0 0 0 0 0 0.5509801615678324 Q12181 0.9512209892272948 0.9387490153312684 0.07144872844219208 1.0 45.35102365753261 40.0 1.0 no 15424 chrXVI_660039r 37455 essential YPR048W 860 - TGTCCGCAATTTCTAACCAA D|293|H D|293|N silent|GCG>GCC|A|292 silent|GCG>GCA|A|292 TAH18 Top1T722A mutant Hypersensitive 623.0 0 0 0 0 0.7375177558431082 Q12181 0.9486550092697144 0.956179976463318 0.0 0.0 46.40159745820307 40.0 1.0 no 15425 chrXVI_660061 37456 essential YPR048W 879 + AAACCATTGAATTTCACCAG P|295|A P|295|S P|295|R P|295|L TAH18 Top1T722A mutant Hypersensitive 623.0 0 0 0 0 0.09631082850990542 Q12181 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.03371299430727959 0.023704906925559044 0.04452770203351975 0.012704082764685154 40.59043351245191 35.0 1.0 no 15426 chrXVI_660085 37458 essential YPR048W 903 + GTTCCTAATGATCTTAAGGA P|303|A P|303|S P|303|R P|303|L TAH18 Top1T722A mutant Hypersensitive 623.0 0 0 0 0 -0.3806245673123409 Q12181 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.815140426158905 0.7189801335334778 0.5291592478752136 0.3978987634181976 42.417605817899535 35.0 1.0 no 15427 chrXVI_660088 37459 essential YPR048W 906 + CCTAATGATCTTAAGGATGG P|303|R P|303|L TAH18 Top1T722A mutant Hypersensitive 623.0 0 0 0 0 -0.3212341960501417 Q12181 0.9432820081710817 0.9430609941482544 0.5291592478752136 0.3978987634181976 41.197601565104385 40.0 1.0 no 15428 chrXVI_660088r 37460 essential YPR048W 909 - CCACCATCCTTAAGATCATT G|309|A G|309|D G|310|R G|310|R TAH18 Top1T722A mutant Hypersensitive 623.0 0 0 0 0 0.8531880439274855 Q12181 0.9499930143356324 0.9446240067481996 0.941340982913971 0.941340982913971 0.13193126022815704 0.031927701085805886 0.35504937171936035 0.35504937171936035 48.45710783108984 40.0 1.0 no 15429 chrXVI_660120r 37461 essential YPR048W 941 - ACAAGTTCCTTAAAGTCATC L|320|F silent|TTG>TTA|L|320 TAH18 Top1T722A mutant Hypersensitive 623.0 0 0 0 0 1.6866144729248431 Q12181 0.9587849974632264 0.09797146916389464 41.42455356610486 35.0 1.0 no 15430 chrXVI_660121r 37462 essential YPR048W 942 - AACAAGTTCCTTAAAGTCAT L|320|F silent|TTG>TTA|L|320 TAH18 Top1T722A mutant Hypersensitive 623.0 0 0 0 0 -0.1516341620211248 Q12181 0.9587849974632264 0.09797146916389464 39.119850288560094 30.0 1.0 no 15431 chrXVI_660424 37466 essential YPR048W 1242 + TACTCTATATCTAGCGGCCC Y|415|* silent|TAC>TAT|Y|415 S|416|C S|416|F TAH18 Top1T722A mutant Hypersensitive 623.0 0 0 0 0 -1.8756156570651827 Q12181 0.945252001285553 0.9294660091400146 0.0 0.0 53.5621592515825 50.0 1.0 no 15432 chrXVI_660530 37473 essential YPR048W 1348 + ACATTGCACGATTGCAAGAG Y|450|* silent|TAC>TAT|Y|450 A|452|G A|452|V TAH18 Top1T722A mutant Hypersensitive 623.0 0 0 0 0 -0.6844245732611627 Q12181 0.9484469890594482 0.9504740238189696 0.4066027402877808 0.22856999933719635 44.138788257879696 45.0 1.0 no 15433 chrXVI_667691r 37475 essential YPR055W 18 - CGTCTTCTCCCCTTCTGCGC R|12|T R|12|K R|11|T R|11|K SEC8 SECretory 1065.0 0 1 0 0 0.09666915330731198 P32855 0.932735025882721 0.955805003643036 0.932735025882721 0.955805003643036 0.5435498356819153 0.2825147211551666 0.0 0.0 64.51432040262932 65.0 1.0 no 15434 chrXVI_667910 37484 essential YPR055W 234 + AATCAATTAAAGTCACAAAT Q|80|E Q|80|* SEC8 SECretory 1065.0 0 0 0 0 -0.4824731835065161 P32855 0.9590039849281312 0.04735297709703445 30.228263875326604 20.0 1.0 no 15435 chrXVI_667966r 37486 essential YPR055W 293 - CCACATTAGTGTTGAACACT V|104|L V|104|M silent|GTG>GTC|V|104 silent|GTG>GTA|V|104 SEC8 SECretory 1065.0 0 0 0 0 0.8204788849619098 P32855 0.9539830088615416 0.9587630033493042 0.06216276064515114 0.011695750057697296 44.91376099916432 40.0 1.0 no 15436 chrXVI_668026r 37489 essential YPR055W 353 - TCAGATTTAAAGTCTGTTCT silent|CTG>CTC|L|124 silent|CTG>CTA|L|124 SEC8 SECretory 1065.0 0 0 0 0 0.5678997412448877 P32855 40.411591541236476 30.0 1.0 no 15437 chrXVI_668305r 37492 essential YPR055W 632 - GTTCTTGTAACTCAAGTTGT E|217|Q E|217|K SEC8 SECretory 1065.0 0 0 0 0 -0.1255946707203695 P32855 0.956179976463318 0.9475290179252625 0.04179349914193154 0.15563242137432098 43.862656420707715 35.0 1.0 no 15438 chrXVI_668429 37493 essential YPR055W 753 + ATCATAAGCATTTCACATAA I|252|M silent|ATC>ATT|I|252 SEC8 SECretory 1065.0 0 0 0 0 0.1139269677007064 P32855 0.9598389863967896 0.16195063292980194 37.10559623052024 25.0 1.0 no 15439 chrXVI_668779 37497 essential YPR055W 1103 + GCACCCTTCTCTGCTTAAAA H|369|Q silent|CAC>CAT|H|369 H|369|D H|369|Y SEC8 SECretory 1065.0 0 0 0 0 -0.4350549881644121 P32855 0.9588389992713928 0.9473130106925964 0.9489949941635132 0.036226220428943634 0.026635276153683662 0.24764147400856015 50.348948723639815 45.0 1.0 no 15440 chrXVI_668760r 37498 essential YPR055W 1087 - GTGCTTCGAACGTATTGATT K|368|N silent|AAG>AAA|K|368 silent|TCG>TCC|S|367 silent|TCG>TCA|S|367 SEC8 SECretory 1065.0 0 0 0 0 0.15287333774750386 P32855 0.9355990290641784 0.20422622561454773 44.73552335816515 40.0 1.0 no 15441 chrXVI_668824 37499 essential YPR055W 1148 + CCATTTTGGCCTACCCGTAC H|384|D H|384|Y SEC8 SECretory 1065.0 0 0 0 0 0.5302536346219411 P32855 0.9473130106925964 0.9489949941635132 0.9485935568809508 0.046278975903987885 57.18631255603885 55.00000000000001 1.0 no 15442 chrXVI_668837r 37501 essential YPR055W 1164 - ATCGATAGTATATCCTGTAC silent|TCG>TCC|S|394 silent|TCG>TCA|S|394 SEC8 SECretory 1065.0 0 0 0 0 0.11409325234428892 P32855 42.5618808092799 35.0 1.0 no 15443 chrXVI_668838r 37502 essential YPR055W 1165 - GATCGATAGTATATCCTGTA silent|TCG>TCC|S|394 silent|TCG>TCA|S|394 SEC8 SECretory 1065.0 0 0 0 0 1.1458777972907594 P32855 43.34873373420714 35.0 1.0 no 15444 chrXVI_668859 37503 essential YPR055W 1183 + TCATTTTAAGGGAATGCTTT I|395|M silent|ATC>ATT|I|395 SEC8 SECretory 1065.0 0 0 0 0 0.50231216552337 P32855 0.9598389863967896 0.029164768755435944 40.77563992780102 30.0 1.0 no 15445 chrXVI_668917r 37504 essential YPR055W 1244 - ACATTTCAAAAATAGCCCTA M|421|I M|421|I E|420|Q E|420|K SEC8 SECretory 1065.0 0 0 0 0 0.6500770266565312 P32855 0.9553959965705872 0.9553959965705872 0.956179976463318 0.9475290179252625 0.8568096160888672 0.8568096160888672 0.02662725932896137 0.021052038297057152 40.26159022089365 30.0 1.0 no 15446 chrXVI_669108 37506 essential YPR055W 1432 + ACGCACCCACTTTACCTAAA A|479|G A|479|V N|478|K silent|AAC>AAT|N|478 SEC8 SECretory 1065.0 0 0 0 0 -0.3812965076659388 P32855 0.9484469890594482 0.9504740238189696 0.9439849853515624 0.35547372698783875 0.2299271672964096 0.9340026974678041 49.43926084412864 45.0 1.0 no 15447 chrXVI_669317r 37507 essential YPR055W 1644 - ACCTTCATGTTGAAAACAGA K|554|N silent|AAG>AAA|K|554 V|555|L V|555|I SEC8 SECretory 1065.0 0 0 0 0 0.6702068077422392 P32855 0.9355990290641784 0.9539830088615416 0.9574310183525084 0.040877636522054665 0.972536325454712 0.7478362917900085 40.558152186920275 35.0 1.0 no 15448 chrXVI_669460r 37509 essential YPR055W 1787 - CCATAGTCATCTGAATCTTT M|602|I M|602|I SEC8 SECretory 1065.0 0 0 0 0 0.03788463309271462 P32855 0.9553959965705872 0.9553959965705872 0.3512406647205353 0.3512406647205353 44.50359351855008 35.0 1.0 no 15449 chrXVI_669475 37510 essential YPR055W 1799 + GACTATGGATTATTTATTCA T|601|S T|601|I SEC8 SECretory 1065.0 0 0 0 0 -0.9028465056400176 P32855 0.9491789937019348 0.9472420215606691 0.18636646866798398 0.006751898676156998 37.79686222904565 25.0 1.0 no 15450 chrXVI_669561 37512 essential YPR055W 1885 + AAACAGCATTAGATTTTCAA T|630|R T|630|I A|631|G A|631|V SEC8 SECretory 1065.0 0 0 0 0 1.2589381150581611 P32855 0.9476869702339172 0.9472420215606691 0.9484469890594482 0.9504740238189696 0.021097596734762192 0.02043602056801319 0.031923260539770126 0.1812958270311356 35.834972818276576 25.0 1.0 no 15451 chrXVI_669667 37513 essential YPR055W 1991 + TCATTTTTATAATTACTACT H|665|D H|665|Y SEC8 SECretory 1065.0 0 0 0 0 0.4278775176494162 P32855 0.9473130106925964 0.9489949941635132 0.023988813161849976 0.023093169555068016 33.50058396780088 15.0 1.0 no 15452 chrXVI_669689 37514 essential YPR055W 2013 + GGGCTATTTAATTCCTTGAT L|673|V silent|CTA>TTA|L|673 SEC8 SECretory 1065.0 0 0 0 0 -1.445870088512513 P32855 0.9512209892272948 0.13772878050804138 45.74470844702654 35.0 1.0 no 15453 chrXVI_669848 37517 essential YPR055W 2172 + ATACCTCATTTCTATCAAGC P|726|A P|726|S P|726|R P|726|L SEC8 SECretory 1065.0 0 0 0 0 0.1365015075151414 P32855 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.11080267280340196 0.40862804651260376 0.05042655020952225 0.03163209930062294 44.320173190168134 35.0 1.0 no 15454 chrXVI_669913 37518 essential YPR055W 2237 + GGACACAATTCTGCAGTTTT D|747|E silent|GAC>GAT|D|747 T|748|R T|748|I SEC8 SECretory 1065.0 0 0 0 0 0.8189655680291862 P32855 0.9532920122146606 0.9476869702339172 0.9472420215606691 0.17543397843837738 0.08381593972444534 0.19949446618556976 46.25780770123714 40.0 1.0 no 15455 chrXVI_669851r 37519 essential YPR055W 2178 - TTACCCGCTTGATAGAAATG G|732|A G|732|D G|732|R G|732|S SEC8 SECretory 1065.0 0 0 0 0 -1.16417625640202 P32855 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.33381205797195435 0.7355624437332153 0.2130679041147232 0.745606541633606 43.057828704767466 40.0 1.0 no 15456 chrXVI_670010r 37520 essential YPR055W 2337 - AATCTATCAGCATCTAACAT R|785|T R|785|K SEC8 SECretory 1065.0 0 0 0 0 0.4718653036218871 P32855 0.932735025882721 0.955805003643036 0.4783611595630646 1.0 39.729344962583006 30.0 1.0 no 15457 chrXVI_671144r 37522 essential YPR056W 21 - GATCTAGCATGCTTAAACGT R|13|T R|13|K TFB4 Transcription Factor B subunit 4 338.0 0 0 0 0 0.30029366597461515 Q12004 0.932735025882721 0.955805003643036 0.6049032807350159 1.0 44.04632641384859 40.0 1.0 no 15458 chrXVI_671225r 37523 essential YPR056W 102 - TCAAAAGTTGTCCATAACTT D|41|H D|41|N TFB4 Transcription Factor B subunit 4 338.0 0 0 0 0 -0.4456863895545192 Q12004 0.9486550092697144 0.956179976463318 0.08845546841621399 0.32122114300727844 39.1226362638817 30.0 1.0 no 15459 chrXVI_671347 37525 essential YPR056W 221 + AGTCATTGCTGCATACTCTC silent|GTC>GTG|V|75 silent|GTC>GTT|V|75 TFB4 Transcription Factor B subunit 4 338.0 0 0 0 0 0.14957901065194176 Q12004 50.866651483116804 45.0 1.0 no 15460 chrXVI_671348 37526 essential YPR056W 222 + GTCATTGCTGCATACTCTCA silent|GTC>GTG|V|75 silent|GTC>GTT|V|75 TFB4 Transcription Factor B subunit 4 338.0 0 0 0 0 -0.029323328697604206 Q12004 52.10187547966319 45.0 1.0 no 15461 chrXVI_671482 37527 essential YPR056W 356 + AAACGTTGATGAGACGCTAG N|120|K silent|AAC>AAT|N|120 TFB4 Transcription Factor B subunit 4 338.0 0 0 0 0 -0.2807231215139601 Q12004 0.9439849853515624 0.5707289576530457 41.26729812927124 45.0 1.0 no 15462 chrXVI_671649 37531 essential YPR056W 523 + GGCTACTTGTTCTTACGTGC L|176|V silent|CTA>TTA|L|176 L|177|V L|177|F TFB4 Transcription Factor B subunit 4 338.0 0 0 0 0 -0.4912270759524604 Q12004 0.9512209892272948 0.9512209892272948 0.9587849974632264 0.3797953426837921 0.024312892928719517 0.09311839193105698 52.635879845773104 50.0 1.0 no 15463 chrXVI_671832 37533 essential YPR056W 706 + TACATGTTGAATCTACAGAA H|237|D H|237|Y TFB4 Transcription Factor B subunit 4 338.0 0 0 0 0 0.6307671414214459 Q12004 0.9473130106925964 0.9489949941635132 0.8176373839378357 0.18220755457878116 36.77175229834893 30.0 1.0 no 15464 chrXVI_690390r 37535 high_effect YPR072W 286 - TGTCTTCATTAGCTTCTCCA K|101|N silent|AAG>AAA|K|101 M|100|I M|100|I NOT5 Negative On TATA 560.0 0 1 0 0 0.5214051973837471 Q12514 0.0 0.07384946942329408 0.07384946942329408 52.24697435857996 40.0 1.0 no 15465 chrXVI_690591r 37536 high_effect YPR072W 487 - TTTCAAGATATTCTCTAGGT L|168|F silent|TTG>TTA|L|168 NOT5 Negative On TATA 560.0 0 1 0 0 -0.2610668737580352 Q12514 0.0 41.28425202892578 30.0 1.0 no 15466 chrXVI_690644r 37537 high_effect YPR072W 540 - TCGTCTTGGAATTCTTCTAC D|187|H D|187|N D|186|H D|186|N NOT5 Negative On TATA 560.0 0 0 0 0 0.2832366833537869 Q12514 0.0 0.0 0.01318258885294199 0.029586296528577805 45.149886589057026 40.0 1.0 no 15467 chrXVI_690645r 37538 high_effect YPR072W 541 - ATCGTCTTGGAATTCTTCTA D|187|H D|187|N D|186|H D|186|N NOT5 Negative On TATA 560.0 0 0 0 0 0.16608513851476853 Q12514 0.0 0.0 0.01318258885294199 0.029586296528577805 44.676431815907726 35.0 1.0 no 15468 chrXVI_690968r 37542 high_effect YPR072W 864 - TCATCTTTCACTGTATGCAA D|295|H D|295|N D|294|H D|294|N NOT5 Negative On TATA 560.0 0 1 0 0 0.5413645338001298 Q12514 0.21775904297828674 0.5298160314559937 0.11211173236370088 0.4512889087200165 44.81458969770529 35.0 1.0 no 15469 chrXVI_691025r 37543 high_effect YPR072W 921 - TTCATAGACACATGTGTAGT M|313|I M|313|I NOT5 Negative On TATA 560.0 0 1 0 0 -0.2343127312506973 Q12514 0.5492729544639587 0.5492729544639587 42.96080969820866 35.0 1.0 no 15470 chrXVI_691090r 37545 high_effect YPR072W 986 - TTTCATCAGTTCTATCCGGT E|335|Q E|335|K D|334|H D|334|N NOT5 Negative On TATA 560.0 0 1 0 0 -0.07690260412933311 Q12514 0.6011834144592285 0.9065303206443788 0.11332978308200835 0.4538678526878357 50.775785608729045 40.0 1.0 no 15471 chrXVI_691075 37546 high_effect YPR072W 968 + GCAACAACTAAATTTCCCAC Q|324|E Q|324|* Q|325|E Q|325|* NOT5 Negative On TATA 560.0 0 0 0 0 -0.3255213265932806 Q12514 1.0 1.0 42.72995394290098 40.0 1.0 no 15472 chrXVI_691170 37548 high_effect YPR072W 1063 + TCAACGACGAATTAAAATAC F|355|L silent|TTC>TTT|F|355 N|356|K silent|AAC>AAT|N|356 NOT5 Negative On TATA 560.0 0 0 0 0 0.038761343690339886 Q12514 1.0 0.9328454732894896 -0.026580000296235085 -1.5877200365066528 31.73375251342594 30.0 1.0 no 15473 chrXVI_691225 37549 high_effect YPR072W 1118 + TCAAGAAATGTCACCAAAGA Q|374|E Q|374|* NOT5 Negative On TATA 560.0 0 1 0 0 1.026814821375727 Q12514 1.0 0.25492000579833984 37.52700510366913 35.0 1.0 no 15474 chrXVI_691238r 37550 high_effect YPR072W 1134 - TCTAATTGCGATACCATCTT E|385|Q E|385|K NOT5 Negative On TATA 560.0 0 0 0 0 0.27451590990427444 Q12514 0.4454732835292816 0.6132003664970398 -0.6448000073432922 -0.5496600270271301 44.4096482231123 35.0 1.0 no 15475 chrXVI_704370r 37551 essential YPR082C 264 + AAGCACATGATGTGTGATTT H|90|D H|90|Y H|90|Q silent|CAC>CAT|H|90 0 0 0 0 -0.041563306836236935 Q06819 0.9508500099182128 0.9510009884834291 0.961404025554657 0.009112536907196043 0.06817898154258728 0.02375411801040173 42.41676758955515 35.0 0.0 no 15476 chrXVI_704377 37552 essential YPR082C 260 - CACACATCATGTGCTTATTG C|93|S C|93|Y M|92|I M|92|I 0 0 0 0 -0.14017760988720918 Q06819 0.9250000119209291 0.9121369719505309 0.9391760230064392 0.9391760230064392 0.0032004700042307377 0.003963741939514875 0.047383002936840064 0.047383002936840064 1.1622600555419922 10.337519645690918 1.918220043182373 1.918220043182373 44.28519294065831 40.0 0.0 no 15477 chrXVI_704562r 37554 essential YPR082C 72 + CGACTTGTTGTCATTCGTTT L|26|V L|26|F 0 0 0 0 0.2716365120878295 Q06819 0.9444829821586608 0.9565489888191224 0.6497982740402222 0.017844190821051598 47.341926636873204 40.0 0.0 no 15478 chrXVI_704573 37555 essential YPR082C 64 - GACAACAAGTCGTTTAGTCT V|28|L V|28|I V|27|L V|27|I 0 0 0 0 -0.16407733137761052 Q06819 0.9478759765625 0.955456018447876 0.9580950140953064 0.9656739830970764 0.17963165044784546 0.37765410542488104 0.12346310168504715 0.09311176091432573 43.567287081864606 40.0 0.0 no 15479 chrXVI_708849r 37557 essential YPR085C 957 + CATCTTCCCTTGAAGAATAT L|321|V L|321|F P|322|A P|322|S ASA1 AStra Associated protein 443.0 0 0 0 0 0.6448673511027218 Q06822 0.9725772142410278 0.07627183943986893 0.09661403298377992 0.1084764376282692 43.2718808795712 35.0 0.0 no 15480 chrXVI_708886 37559 essential YPR085C 923 - CACTGACTCTCAGTGAGCTT S|314|T S|314|N V|313|L V|313|I ASA1 AStra Associated protein 443.0 0 0 0 0 -1.0141987148321752 Q06822 0.6507733464241028 0.33926281332969666 0.3721962571144104 0.8308082818984985 51.46968382351741 50.0 0.0 no 15481 chrXVI_708916 37560 essential YPR085C 893 - TCAAAAGCGCATCATCTCTA L|304|F silent|TTG>TTA|L|304 ASA1 AStra Associated protein 443.0 0 0 0 0 0.609273871698317 Q06822 0.7506808638572693 44.22039932667428 40.0 0.0 no 15482 chrXVI_708945 37561 essential YPR085C 864 - GTCTCAAGTTGTAAGTTCAC E|294|D silent|GAG>GAA|E|294 E|294|Q E|294|K ASA1 AStra Associated protein 443.0 0 0 0 0 0.8135971907391015 Q06822 0.6125618815422058 0.585059404373169 0.9356581568717957 44.164957988489505 40.0 0.0 no 15483 chrXVI_709019r 37563 essential YPR085C 787 + TACTTGATATGTGTGTTAGC L|264|V L|264|F ASA1 AStra Associated protein 443.0 0 0 0 0 -0.8247940409159399 Q06822 0.0 0.0 42.67004321778137 35.0 0.0 no 15484 chrXVI_709029 37565 essential YPR085C 780 - CACATATCAAGTATTGGATT M|266|I M|266|I ASA1 AStra Associated protein 443.0 0 0 0 0 0.8226227808865623 Q06822 0.10499019920825957 0.10499019920825957 38.645440259069524 30.0 0.0 no 15485 chrXVI_709078 37567 essential YPR085C 731 - GTTCTGCAATGTCCCTTTGA E|250|Q E|250|K A|249|P A|249|T ASA1 AStra Associated protein 443.0 0 0 0 0 -0.3576080188029676 Q06822 0.18889273703098294 0.2280310392379761 0.04000383242964745 0.13365782797336578 53.19242518973732 45.0 0.0 no 15486 chrXVI_709228 37569 essential YPR085C 581 - TCTGCTGCTTCAAGAATCTG Q|200|H silent|CAG>CAA|Q|200 Q|199|H silent|CAG>CAA|Q|199 ASA1 AStra Associated protein 443.0 0 0 0 0 -0.028086467144283308 Q06822 0.15486983954906464 0.4446897804737091 46.581728266019404 45.0 0.0 no 15487 chrXVI_709324r 37571 essential YPR085C 482 + TTGCTGTCATACTGATGATT C|162|W silent|TGC>TGT|C|162 ASA1 AStra Associated protein 443.0 0 0 0 0 0.986062159677629 Q06822 0.0027356338687241077 44.119333352051505 35.0 0.0 no 15488 chrXVI_709406 37572 essential YPR085C 403 - CGCAAAATTCAGTGTGTTTA A|141|P A|141|T ASA1 AStra Associated protein 443.0 0 0 0 0 -0.02334121182888542 Q06822 0.0 0.0 41.11664162601386 35.0 0.0 no 15489 chrXVI_709356 37573 essential YPR085C 453 - TAACTTTTATTATCTTTGGT S|157|T S|157|N ASA1 AStra Associated protein 443.0 0 0 0 0 0.7191661133854651 Q06822 0.6624752879142761 0.5451062321662903 37.31856748586699 20.0 0.0 no 15490 chrXVI_709407 37574 essential YPR085C 402 - GCAAAATTCAGTGTGTTTAT A|141|P A|141|T ASA1 AStra Associated protein 443.0 0 0 0 0 -1.1745390345590958 Q06822 0.0 0.0 39.707364468504075 30.0 0.0 no 15491 chrXVI_709586r 37576 essential YPR085C 220 + CGCACATTATAGCGTTTTGG H|75|D H|75|Y H|75|Q silent|CAC>CAT|H|75 ASA1 AStra Associated protein 443.0 0 0 0 0 0.07125335275387562 Q06822 0.0353027880191803 0.03991715610027313 1.0 46.86979024475796 45.0 0.0 no 15492 chrXVI_709589r 37577 essential YPR085C 217 + ACTCGCACATTATAGCGTTT S|74|W S|74|L N|73|K silent|AAC>AAT|N|73 ASA1 AStra Associated protein 443.0 0 0 0 0 -1.0140599401073918 Q06822 0.016092278063297268 0.11543980240821837 0.7410035729408264 47.51082124174701 40.0 0.0 no 15493 chrXVI_709617 37578 essential YPR085C 192 - TCGATTTCTATATGTGTAAT E|71|Q E|71|K ASA1 AStra Associated protein 443.0 0 0 0 0 0.5970213227285223 Q06822 0.4560054242610931 0.7218925356864929 37.74646459114979 25.0 0.0 no 15494 chrXVI_709657r 37579 essential YPR085C 149 + CTACGGTTATTTCGTTATGT Y|51|* silent|TAC>TAT|Y|51 ASA1 AStra Associated protein 443.0 0 0 0 0 0.1160942919915952 Q06822 44.272809425039846 35.0 0.0 no 15495 chrXVI_709751r 37583 essential YPR085C 55 + TCACCTTACGTTACCATAAA T|20|S T|20|I F|19|L silent|TTC>TTT|F|19 ASA1 AStra Associated protein 443.0 0 0 0 0 -0.5012348345364767 Q06822 0.22040602564811707 0.008607986383140087 0.18033598363399506 43.360260477512895 35.0 0.0 no 15496 chrXVI_710190r 37584 essential YPR086W 92 - ATCTTTCAACGATTTTTGGT R|37|T R|37|K E|36|Q E|36|K SUA7 Suppressor of Upstream AUG 345.0 0 0 0 0 0.12321439749237395 P29055 0.10199853032827376 0.31124743819236755 0.0 0.0 42.16065188901223 30.0 1.0 no 15497 chrXVI_710191r 37585 essential YPR086W 93 - AATCTTTCAACGATTTTTGG R|37|T R|37|K SUA7 Suppressor of Upstream AUG 345.0 0 0 0 0 0.32060368257677674 P29055 0.10199853032827376 0.31124743819236755 38.408832814655455 30.0 1.0 no 15498 chrXVI_710200 37586 essential YPR086W 99 + ATCGTTGAAAGATTTAGTGA I|34|M silent|ATC>ATT|I|34 SUA7 Suppressor of Upstream AUG 345.0 0 0 0 0 0.06948594872672997 P29055 0.02639632485806942 -0.5189999938011169 37.50610530269148 30.0 1.0 no 15499 chrXVI_710276r 37589 essential YPR086W 178 - AAACGTTCTCCACTCCGACC silent|ACG>ACC|T|65 silent|ACG>ACA|T|65 SUA7 Suppressor of Upstream AUG 345.0 0 0 0 0 0.7756017754267528 P29055 52.58193229825185 55.00000000000001 1.0 no 15500 chrXVI_710322 37590 essential YPR086W 221 + TGACCCAAGTCGTGTTGGTG D|75|E silent|GAC>GAT|D|75 P|76|A P|76|S SUA7 Suppressor of Upstream AUG 345.0 0 0 0 0 -0.5011213939820098 P29055 0.0 0.0 0.0 53.29411744705891 55.00000000000001 1.0 no 15501 chrXVI_710325r 37591 essential YPR086W 227 - AAGCCTCACCAACACGACTT A|82|P A|82|T E|81|D silent|GAG>GAA|E|81 SUA7 Suppressor of Upstream AUG 345.0 0 0 0 0 -0.5962521678795643 P29055 0.19863183796405792 0.03659376129508018 0.705224335193634 -0.7116000056266785 0.5550000071525574 50.092284389876276 50.0 1.0 no 15502 chrXVI_710344 37592 essential YPR086W 243 + GCTTCAAATCCTCTTTTAGA A|82|G A|82|V S|83|* S|83|L SUA7 Suppressor of Upstream AUG 345.0 0 0 0 0 -0.8483134672890257 P29055 0.17145124077796936 0.09447858482599257 0.2158900797367096 0.4241999983787537 0.550000011920929 45.165344533868115 35.0 1.0 no 15503 chrXVI_710345 37593 essential YPR086W 244 + CTTCAAATCCTCTTTTAGAT S|83|* S|83|L SUA7 Suppressor of Upstream AUG 345.0 0 0 0 0 -0.24372545837687945 P29055 0.2158900797367096 41.48269164450687 30.0 1.0 no 15504 chrXVI_710415 37596 essential YPR086W 314 + ATTCACCAAAGAACTGAATA F|106|L silent|TTC>TTT|F|106 T|107|S T|107|I SUA7 Suppressor of Upstream AUG 345.0 0 0 0 0 0.4822625917281162 P29055 0.7391824722290039 0.4627124667167664 0.21073117852211 -0.4663999974727631 36.31170698178392 30.0 1.0 no 15505 chrXVI_710527r 37597 essential YPR086W 429 - GCACAATCTTTCACAATCTT C|149|S C|149|Y A|150|P A|150|T SUA7 Suppressor of Upstream AUG 345.0 0 0 0 0 0.4688134227758198 P29055 0.41113045811653137 1.0 0.010089177638292313 0.01281613390892744 0.4670000076293945 -1.701200008392334 43.340118167898815 35.0 1.0 no 15506 chrXVI_710549r 37598 essential YPR086W 451 - GCAAAGTTTATATGCTTCCT C|157|S C|157|Y SUA7 Suppressor of Upstream AUG 345.0 0 0 0 0 0.3295714263478437 P29055 0.05269913747906685 0.008804528973996641 0.973200023174286 -0.5730000138282776 45.51320633659122 35.0 1.0 no 15507 chrXVI_710818r 37602 essential YPR086W 720 - CCCAGATGCGAACAAAACCT silent|CTG>CTC|L|246 silent|CTG>CTA|L|246 G|247|R G|247|S SUA7 Suppressor of Upstream AUG 345.0 0 0 0 0 -0.3270930965697388 P29055 0.28133609890937805 0.4028609395027161 46.91359444513882 50.0 1.0 no 15508 chrXVI_710876r 37604 essential YPR086W 778 - GATCTCTTTACATTTCTTTG E|265|D silent|GAG>GAA|E|265 E|265|Q E|265|K SUA7 Suppressor of Upstream AUG 345.0 0 0 0 0 0.3795874457902497 P29055 0.690727949142456 0.49458047747612 0.779872715473175 41.38006391745222 30.0 1.0 no 15509 chrXVI_711791 37605 essential YPR088C 1218 - GCTACACGAACCATTCTTGT A|413|P A|413|T V|412|L V|412|I SRP54 Signal Recognition Particle 54-kD subunit 541.0 0 0 0 0 -1.7403849081136664 P20424 0.9573720097541808 0.9523990154266356 0.9539830088615416 0.9574310183525084 0.015778088942170143 0.010897195897996427 0.03276953101158142 1.0 48.55992564227995 45.0 0.0 no 15510 chrXVI_711923 37606 essential YPR088C 1086 - TTCATCATATTACTCATACC M|368|I M|368|I M|367|I M|367|I SRP54 Signal Recognition Particle 54-kD subunit 541.0 0 1 0 0 0.758031575417506 P20424 0.9553959965705872 0.9553959965705872 0.9553959965705872 0.9553959965705872 0.5187657475471497 0.5187657475471497 0.3210136294364929 0.3210136294364929 41.433313797356895 30.0 0.0 no 15511 chrXVI_712051 37610 essential YPR088C 958 - GGCTTTTGCATCTTCCTTGT A|326|P A|326|T SRP54 Signal Recognition Particle 54-kD subunit 541.0 0 0 0 0 0.502199696343072 P20424 0.9573720097541808 0.9523990154266356 0.043851029127836234 0.05629955232143403 56.10219058917801 45.0 0.0 no 15512 chrXVI_712118r 37611 essential YPR088C 888 + TCATTCATATCTAAACTGTT S|297|* S|297|L F|298|L silent|TTC>TTT|F|298 SRP54 Signal Recognition Particle 54-kD subunit 541.0 0 0 0 0 0.8593509952919087 P20424 0.9298099875450134 0.9387490153312684 0.07306395471096039 0.0 0.24442000687122345 37.64709935649182 25.0 0.0 no 15513 chrXVI_712178r 37613 essential YPR088C 828 + CCGATTATCTTTATTGGTAC P|277|R P|277|L SRP54 Signal Recognition Particle 54-kD subunit 541.0 0 0 0 0 -0.4439599135145091 P20424 0.9432820081710817 0.9430609941482544 0.0 0.0 43.05805552391348 35.0 0.0 no 15514 chrXVI_712277r 37620 essential YPR088C 729 + TTCAAAGAATCGTCCGATTT F|244|L silent|TTC>TTT|F|244 SRP54 Signal Recognition Particle 54-kD subunit 541.0 0 0 0 0 1.2004179287153982 P20424 0.9387490153312684 0.0 41.31277191830589 35.0 0.0 no 15515 chrXVI_712423r 37622 essential YPR088C 583 + TCATCGTTGATACTTCAGGT I|195|M silent|ATC>ATT|I|195 I|196|M silent|ATC>ATT|I|196 SRP54 Signal Recognition Particle 54-kD subunit 541.0 0 1 0 0 0.4885245652117321 P20424 0.9598389863967896 0.9598389863967896 0.0024811597540974613 0.004297889303416014 47.10426639013855 40.0 0.0 no 15516 chrXVI_712482 37625 essential YPR088C 527 - CTTCTTCTGCAACTTTGGCA E|182|Q E|182|K E|181|Q E|181|K SRP54 Signal Recognition Particle 54-kD subunit 541.0 0 1 0 0 0.3879322459439432 P20424 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.2388046532869339 0.1795869916677475 0.5828565955162048 0.936446249485016 50.93600742127211 45.0 0.0 no 15517 chrXVI_712512r 37626 essential YPR088C 494 + TCCATTTTATGGGTCATATA P|166|R P|166|L P|166|A P|166|S SRP54 Signal Recognition Particle 54-kD subunit 541.0 0 0 0 0 -0.08773200199132536 P20424 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.12684643268585205 0.014886990189552309 0.021927736699581143 0.02034592255949974 44.06876464624628 30.0 0.0 no 15518 chrXVI_712682r 37630 essential YPR088C 324 + ACAAACATCATCATGTTTGT T|109|R T|109|I N|110|K silent|AAC>AAT|N|110 SRP54 Signal Recognition Particle 54-kD subunit 541.0 0 0 0 0 -0.841261135573605 P20424 0.9476869702339172 0.9472420215606691 0.9439849853515624 0.5851492881774902 0.15857239067554474 0.01109757274389267 39.84968503622547 30.0 0.0 no 15519 chrXVI_712481 37632 essential YPR088C 528 - CCTTCTTCTGCAACTTTGGC G|183|R G|183|S E|182|Q E|182|K SRP54 Signal Recognition Particle 54-kD subunit 541.0 0 1 0 0 -0.4224680684165162 P20424 0.941340982913971 0.951104998588562 0.956179976463318 0.9475290179252625 0.0 0.0 0.2388046532869339 0.1795869916677475 53.48010209888707 50.0 0.0 no 15520 chrXVI_712925r 37633 essential YPR088C 81 + TCCGTAGATGTAATGTTAAA silent|TCC>TCG|S|28 silent|TCC>TCT|S|28 S|28|C S|28|F SRP54 Signal Recognition Particle 54-kD subunit 541.0 0 0 0 1 0.9366825265298104 P20424 0.945252001285553 0.9294660091400146 0.053932327777147286 0.06168287619948388 38.445551718758004 30.0 0.0 no 15521 chrXVI_720645r 37634 essential YPR094W 11 - ACATTATTAGATCAAACTGA M|10|I M|10|I RDS3 Regulator of Drug Sensitivity 107.0 0 0 0 0 -0.23137660768766585 Q06835 0.9553959965705872 0.9553959965705872 0.14696663618087769 0.14696663618087769 0.543179988861084 0.543179988861084 2.9148800373077397 2.9148800373077397 34.68628360627423 25.0 1.0 no 15522 chrXVI_720669r 37636 essential YPR094W 35 - TCTGTACACCAGGCTGCTTT Q|18|H silent|CAG>CAA|Q|18 V|17|L V|17|I RDS3 Regulator of Drug Sensitivity 107.0 0 0 0 0 0.4634186328190954 Q06835 0.9570760130882264 0.9539830088615416 0.9574310183525084 0.34586676955223083 0.2225131392478943 0.7957010269165039 -0.13298000395298004 -0.21235999464988708 0.2017199993133545 0.06295999884605408 -0.4512200057506561 55.78607627901869 50.0 1.0 no 15523 chrXVI_720697 37637 essential YPR094W 60 + CTTCTTTGTGAAAAATGTGA L|22|V L|22|F RDS3 Regulator of Drug Sensitivity 107.0 0 0 0 0 0.524536419607784 Q06835 0.9512209892272948 0.9587849974632264 0.6503210663795471 0.014755806885659696 1.481320023536682 10.399840354919434 2.2379000186920166 6.581379890441895 36.34869376707741 30.0 1.0 no 15524 chrXVI_720752r 37638 essential YPR094W 118 - ACATACTCTAACTTTCCTTT C|46|S C|46|Y V|45|L V|45|I RDS3 Regulator of Drug Sensitivity 107.0 0 0 0 0 0.12031158158579555 Q06835 0.9421560168266296 0.9290120005607604 0.9539830088615416 0.9574310183525084 0.010497826151549816 0.0008634197874926032 0.2324708104133606 1.0 6.15447998046875 16.651979446411133 1.1553399562835691 -0.4898599982261658 0.5357000231742859 9.821020126342773 -0.18880000710487368 -0.8434000015258789 43.36081574676064 30.0 1.0 no 15525 chrXVI_720867r 37640 essential YPR094W 233 - CATCTTTATCTTTACCTAAG D|84|H D|84|N RDS3 Regulator of Drug Sensitivity 107.0 0 0 0 0 0.2254431498995953 Q06835 0.9486550092697144 0.956179976463318 0.0068277628161013135 0.155867800116539 -0.4326600134372711 -0.4326199889183045 40.107304482155364 30.0 1.0 no 15526 chrXVI_732487r 37643 essential YPR103W 141 - TGCTGTGGAGACGCAATTGG Q|53|H silent|CAG>CAA|Q|53 PRE2 PRoteinase yscE 287.0 0 1 0 0 -0.5613444151856235 P30656 0.11869224905967712 49.67281344616538 55.00000000000001 1.0 no 15527 chrXVI_732580 37645 essential YPR103W 231 + ACCTTAGCATTTAGATTTCA silent|ACC>ACG|T|78 silent|ACC>ACT|T|78 T|78|S T|78|I PRE2 PRoteinase yscE 287.0 0 0 0 1 0.9888460334899244 P30656 0.017210530117154118 0.002134503331035376 1.2496559619903564 -2.472491979598999 44.10380453459385 30.0 1.0 no 15528 chrXVI_732581r 37646 essential YPR103W 235 - GCCTTGAAATCTAAATGCTA G|85|R G|85|S G|85|A G|85|D PRE2 PRoteinase yscE 287.0 0 0 0 0 0.7953375041301489 P30656 0.07031574845314026 0.1668766438961029 0.15552477538585666 0.5547071695327759 0.7202519774436951 1.2598119974136353 0.8259493708610535 1.253610610961914 41.320765714974364 35.0 1.0 no 15529 chrXVI_732812r 37654 essential YPR103W 466 - TACTAAATTGCTTAAAATCT V|162|L V|162|I PRE2 PRoteinase yscE 287.0 0 1 0 0 0.3444656517874343 P30656 0.6213173270225525 0.10708196461200714 -1.4528340101242063 0.29772600531578064 -2.253659963607788 -0.8031600117683411 32.09154720253031 20.0 1.0 no 15530 chrXVI_732964 37661 essential YPR103W 615 + TCAGGTCAAACATTTGCATA S|206|* S|206|L Q|208|E Q|208|* PRE2 PRoteinase yscE 287.0 0 0 0 0 -0.044622142255182656 P30656 0.0019080206984654071 0.01789248734712601 42.44019503429712 35.0 1.0 no 15531 chrXVI_734441r 37667 essential YPR104C 1970 + TACACAAGCGGCAAAAAACA T|658|R T|658|I Q|659|E Q|659|* FHL1 Fork Head-Like 936.0 0 0 0 0 -0.5579458968686719 P39521 0.006217136513441801 0.005200252868235111 0.05538731440901756 38.31488195979222 40.0 0.0 no 15532 chrXVI_734465r 37668 essential YPR104C 1946 + TCTAGCTATGACAATAAATC L|650|V silent|CTA>TTA|L|650 A|651|G A|651|V FHL1 Fork Head-Like 936.0 0 0 0 0 -0.5096246624300641 P39521 0.021985962986946102 0.059475347399711616 0.025310706347227097 35.49868540903583 30.0 0.0 no 15533 chrXVI_734595 37669 essential YPR104C 1819 - TGCTGTATTTTTCCTGTTCG A|613|P A|613|T FHL1 Fork Head-Like 936.0 0 0 0 0 1.0131350635477183 P39521 0.27131518721580505 0.5872349143028259 49.51305402825381 40.0 0.0 no 15534 chrXVI_734580r 37670 essential YPR104C 1831 + ATACAGCAAGTGATAATCAA T|612|R T|612|I A|613|G A|613|V FHL1 Fork Head-Like 936.0 0 0 0 0 0.1891888907188116 P39521 0.5615522861480713 0.22679638862609866 0.4368484318256378 0.340107798576355 36.687678866530796 30.0 0.0 no 15535 chrXVI_734867r 37674 essential YPR104C 1544 + GCTAAATAAATCTTTCAGGA L|516|V silent|CTA>TTA|L|516 FHL1 Fork Head-Like 936.0 0 0 0 0 0.8772605045836123 P39521 0.0 37.094484349879 30.0 0.0 no 15536 chrXVI_734973 37676 essential YPR104C 1441 - TTCAGATAAAGACATTCCCT E|487|Q E|487|K FHL1 Fork Head-Like 936.0 0 0 0 0 -1.4472587553443268 P39521 0.0 0.0 43.276445221533315 35.0 0.0 no 15537 chrXVI_734990r 37677 essential YPR104C 1421 + ACGAAAGTACTCGACTGCCA R|475|G R|475|* FHL1 Fork Head-Like 936.0 0 0 0 0 0.2069893252891013 P39521 0.006143329665064812 47.57159083187286 50.0 0.0 no 15538 chrXVI_734923 37678 essential YPR104C 1491 - TCAGGACAGTATTTATAATA D|504|H D|504|N C|502|S C|502|Y FHL1 Fork Head-Like 936.0 0 0 0 0 0.012900963464559628 P39521 0.0 0.0 0.0 0.0 36.09214157123915 25.0 0.0 no 15539 chrXVI_735091 37679 essential YPR104C 1323 - ACTTTCTTTGGTATTTTCGG V|448|L V|448|I K|446|N silent|AAG>AAA|K|446 FHL1 Fork Head-Like 936.0 0 0 0 0 -0.061422094102595325 P39521 0.0 0.0 0.009805257432162762 45.112456210816724 35.0 0.0 no 15540 chrXVI_735115 37680 essential YPR104C 1299 - TTCTTTTCTTTCTTAACAGC K|439|N silent|AAG>AAA|K|439 FHL1 Fork Head-Like 936.0 0 0 0 0 1.3469672279471765 P39521 0.4507388174533844 42.725611574262416 30.0 0.0 no 15541 chrXVI_735120 37681 essential YPR104C 1294 - TTCTTTCTTAACAGCTGGTT E|438|Q E|438|K K|436|N silent|AAG>AAA|K|436 FHL1 Fork Head-Like 936.0 0 0 0 0 -0.21702082971578607 P39521 0.3237392604351044 0.35684239864349365 0.2209208756685257 46.384682572850465 35.0 0.0 no 15542 chrXVI_735232 37682 essential YPR104C 1182 - TCTGCTATGTCAGCGTTTTC E|401|Q E|401|K A|400|P A|400|T FHL1 Fork Head-Like 936.0 0 0 0 0 0.5480208043435765 P39521 0.467602550983429 0.730215311050415 0.4629676640033722 0.7079818844795227 51.552641259063705 45.0 0.0 no 15543 chrXVI_735166r 37683 essential YPR104C 1245 + TCTAAGAAAAAGATTACAAC S|416|C S|416|F FHL1 Fork Head-Like 936.0 0 0 0 0 -0.4689983013927162 P39521 0.05244089290499687 0.050536785274744034 28.58079587155038 25.0 0.0 no 15544 chrXVI_735233 37684 essential YPR104C 1181 - CTGCTATGTCAGCGTTTTCT A|400|P A|400|T FHL1 Fork Head-Like 936.0 0 0 0 0 0.8214155469330962 P39521 0.4629676640033722 0.7079818844795227 52.29184573642983 45.0 0.0 no 15545 chrXVI_735384 37685 essential YPR104C 1030 - AGCACCATTCTTCCCTATTA A|350|P A|350|T G|349|A G|349|D FHL1 Fork Head-Like 936.0 0 0 0 0 -1.0978393583017243 P39521 0.0 0.0 0.0 0.0 52.86518122518596 40.0 0.0 no 15546 chrXVI_735478r 37686 essential YPR104C 933 + CACAAAGTTGACGTTAATCT H|312|Q silent|CAC>CAT|H|312 FHL1 Fork Head-Like 936.0 0 0 0 0 0.1259606840840587 P39521 0.02787487767636776 38.82501240773177 35.0 0.0 no 15547 chrXVI_735579r 37689 essential YPR104C 832 + CGACTATCTTCGCCTATGCA T|279|S T|279|I FHL1 Fork Head-Like 936.0 0 0 0 0 0.16011131699202932 P39521 0.5537952780723572 0.09431970119476317 52.00168138824718 50.0 0.0 no 15548 chrXVI_735636 37692 essential YPR104C 778 - TGGCTCAGATAGTTTTCGTT E|265|D silent|GAG>GAA|E|265 E|265|Q E|265|K FHL1 Fork Head-Like 936.0 0 1 0 0 -0.09803945083477766 P39521 0.6129987239837646 0.5886224508285522 0.8482373952865601 48.74157453965967 40.0 0.0 no 15549 chrXVI_735686r 37694 essential YPR104C 725 + ACCGCCACAAAACACTGTAA P|243|R P|243|L P|243|A P|243|S FHL1 Fork Head-Like 936.0 0 1 0 0 -1.001692563031458 P39521 0.5039132237434387 0.3519429266452789 0.7172725200653076 0.7542686462402344 45.129240255616814 45.0 0.0 no 15550 chrXVI_735712r 37695 essential YPR104C 699 + TTTCAGCAGCATGAATTAGT Q|235|E Q|235|* Q|236|E Q|236|* FHL1 Fork Head-Like 936.0 0 1 0 0 -0.4295798634062807 P39521 0.2805714607238769 0.5433359146118164 44.04023357601704 35.0 0.0 no 15551 chrXVI_735782 37697 essential YPR104C 632 - TTTCATCTACTAATGTTGGT E|217|Q E|217|K D|216|H D|216|N FHL1 Fork Head-Like 936.0 0 0 0 0 -0.11802832053603562 P39521 0.10148799419403076 0.12339867651462555 0.5900056958198547 0.6528071761131287 42.03497652690504 30.0 0.0 no 15552 chrXVI_735783 37698 essential YPR104C 631 - TTCATCTACTAATGTTGGTA E|217|Q E|217|K D|216|H D|216|N FHL1 Fork Head-Like 936.0 0 0 0 0 -0.5036187977205789 P39521 0.10148799419403076 0.12339867651462555 0.5900056958198547 0.6528071761131287 41.18595765501596 30.0 0.0 no 15553 chrXVI_735944 37699 essential YPR104C 470 - TCTCCCTTTCGTCCTCATCA E|163|Q E|163|K E|163|D silent|GAG>GAA|E|163 FHL1 Fork Head-Like 936.0 0 1 0 0 -0.3391973335070195 P39521 0.5734756588935852 0.9027681946754456 0.6365674734115601 59.50280977338178 50.0 0.0 no 15554 chrXVI_735952 37702 essential YPR104C 462 - TCGTCCTCATCAGGGTTTAC E|161|Q E|161|K D|160|H D|160|N FHL1 Fork Head-Like 936.0 0 1 0 0 0.3719453494003313 P39521 0.3921475410461426 0.5209455490112305 0.15048332512378693 0.7220016121864319 53.548377959350546 50.0 0.0 no 15555 chrXVI_736112r 37704 essential YPR104C 299 + CGCTGATTTTTCGAAGCTAC A|101|G A|101|V FHL1 Fork Head-Like 936.0 0 0 0 0 1.3788558784473184 P39521 45.45448005508831 45.0 0.0 no 15556 chrXVI_736121 37705 essential YPR104C 293 - TCGAAAAATCAGCGTTATCA silent|TCG>TCC|S|104 silent|TCG>TCA|S|104 FHL1 Fork Head-Like 936.0 0 0 0 0 0.2360436583093973 P39521 38.92556609650808 35.0 0.0 no 15557 chrXVI_736129 37706 essential YPR104C 285 - TCAGCGTTATCAAGGTTATC D|102|H D|102|N A|101|P A|101|T FHL1 Fork Head-Like 936.0 0 0 0 0 -0.9203543355320888 P39521 0.13083919882774353 0.09389951825141908 45.16959218104864 40.0 0.0 no 15558 chrXVI_736168 37707 essential YPR104C 246 - TTTCCATTATCGTCTGTAAC G|88|A G|88|E G|88|R G|88|R FHL1 Fork Head-Like 936.0 0 1 0 0 0.5766343839864903 P39521 44.01271451769895 35.0 0.0 no 15559 chrXVI_736171r 37708 essential YPR104C 240 + AATCCTGTTACAGACGATAA P|82|A P|82|S P|82|R P|82|L FHL1 Fork Head-Like 936.0 0 1 0 0 -0.22434171276473508 P39521 1.0 0.6778312921524048 0.3404183089733124 0.4276162683963776 40.66332767480935 35.0 0.0 no 15560 chrXVI_736279 37709 essential YPR104C 135 - TCAATCGGTACCTCGCTTGT E|52|Q E|52|K silent|CCG>CCC|P|50 silent|CCG>CCA|P|50 FHL1 Fork Head-Like 936.0 0 1 0 0 -1.3624515330427316 P39521 52.950726035523424 50.0 0.0 no 15561 chrXVI_737686 37711 essential YPR105C 1864 - ATCGTCTTCTAATATTTCTA D|628|H D|628|N D|627|H D|627|N COG4 Conserved Oligomeric Golgi complex 861.0 0 0 0 0 0.1950110096745282 Q06096 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.03576942905783653 1.0 0.053108040243387215 0.13707712292671204 39.76939335377665 25.0 0.0 no 15562 chrXVI_737921 37713 essential YPR105C 1629 - GCAGATTGCTCCTCACCTTT A|550|P A|550|T COG4 Conserved Oligomeric Golgi complex 861.0 0 0 0 0 0.3358824676811159 Q06096 0.9573720097541808 0.9523990154266356 0.21782709658145905 0.418513298034668 57.13884574375726 50.0 0.0 no 15563 chrXVI_738132 37716 essential YPR105C 1418 - CATCTAAAACAGATGTTACA D|479|H D|479|N COG4 Conserved Oligomeric Golgi complex 861.0 0 0 0 0 0.6003518274981228 Q06096 0.9486550092697144 0.956179976463318 0.0070669203996658325 0.015223635360598562 35.65149988854512 30.0 0.0 no 15564 chrXVI_738323r 37719 essential YPR105C 1224 + CCACCTCCACCAATAGCAGA P|410|A P|410|S P|409|R P|409|L COG4 Conserved Oligomeric Golgi complex 861.0 0 0 0 0 0.1376987530002141 Q06096 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.1809660494327545 0.07999324053525925 0.05426475778222084 1.0 55.657015653254525 55.00000000000001 0.0 no 15565 chrXVI_738415r 37720 essential YPR105C 1132 + TTTCTCAAATACTTCAAAAT S|379|C S|379|F Q|380|E Q|380|* COG4 Conserved Oligomeric Golgi complex 861.0 0 0 0 0 0.629021792330775 Q06096 0.945252001285553 0.9294660091400146 0.9590039849281312 0.0 0.0 0.8660997152328491 32.38257742837027 20.0 0.0 no 15566 chrXVI_738876 37721 essential YPR105C 674 - GTACGTCCTGCCCAATCATA V|231|L V|231|I D|230|H D|230|N COG4 Conserved Oligomeric Golgi complex 861.0 0 0 0 0 0.8160723936558321 Q06096 0.9539830088615416 0.9574310183525084 0.9486550092697144 0.956179976463318 0.24949416518211365 0.1547420471906662 0.0746394470334053 0.9065973162651062 54.469038183707816 50.0 0.0 no 15567 chrXVI_738886r 37722 essential YPR105C 661 + TCAAAATGTTCCCTATGATT F|221|L silent|TTC>TTT|F|221 COG4 Conserved Oligomeric Golgi complex 861.0 0 0 0 0 0.8862117757920196 Q06096 0.9387490153312684 0.0 41.318520492971636 30.0 0.0 no 15568 chrXVI_738887r 37723 essential YPR105C 660 + TTCAAAATGTTCCCTATGAT F|221|L silent|TTC>TTT|F|221 COG4 Conserved Oligomeric Golgi complex 861.0 0 0 0 0 0.9792812311951028 Q06096 0.9387490153312684 0.0 41.318520492971636 30.0 0.0 no 15569 chrXVI_738984r 37724 essential YPR105C 563 + ACTAATAAAGAATTGGTGTA L|189|V silent|CTA>TTA|L|189 COG4 Conserved Oligomeric Golgi complex 861.0 0 0 0 0 0.04797639003878579 Q06096 0.9512209892272948 0.2475759834051132 33.256615753851754 25.0 0.0 no 15570 chrXVI_738991r 37725 essential YPR105C 556 + CAGCTATACTAATAAAGAAT A|187|G A|187|V COG4 Conserved Oligomeric Golgi complex 861.0 0 0 0 0 0.8889253021104561 Q06096 0.9484469890594482 0.9504740238189696 0.23707498610019684 0.30377331376075745 32.23552498837074 25.0 0.0 no 15571 chrXVI_739039 37728 essential YPR105C 511 - CACAACTTTCTTGGCAAACT V|177|L V|177|M V|176|L V|176|I COG4 Conserved Oligomeric Golgi complex 861.0 0 0 0 0 0.6114285048824473 Q06096 0.9539830088615416 0.9587630033493042 0.9539830088615416 0.9574310183525084 0.08681320399045944 0.017842136323451996 0.2343892306089401 0.3058840334415436 43.274619462347744 40.0 0.0 no 15572 chrXVI_739152r 37730 essential YPR105C 395 + GCTAAAGAATAATATTTCAC L|133|V silent|CTA>TTA|L|133 COG4 Conserved Oligomeric Golgi complex 861.0 0 0 0 0 0.6140832749657404 Q06096 0.9512209892272948 0.0 32.196536242704894 25.0 0.0 no 15573 chrXVI_739290r 37732 essential YPR105C 257 + GACTCAGTTTCATGAGACTG T|87|S T|87|I Q|88|E Q|88|* COG4 Conserved Oligomeric Golgi complex 861.0 0 0 0 0 -0.1124117518197208 Q06096 0.9491789937019348 0.9472420215606691 0.9590039849281312 1.0 0.014691288582980631 0.7331163883209229 45.17214298956941 45.0 0.0 no 15574 chrXVI_739332 37733 essential YPR105C 218 - TTCTTTGCAATTCTAATTTC R|79|T R|79|K COG4 Conserved Oligomeric Golgi complex 861.0 0 0 0 0 0.2783393966711749 Q06096 0.932735025882721 0.955805003643036 0.011996259912848473 0.1945286840200424 38.577327553754685 25.0 0.0 no 15575 chrXVI_739333 37734 essential YPR105C 217 - TCTTTGCAATTCTAATTTCC R|79|T R|79|K L|77|F silent|TTG>TTA|L|77 COG4 Conserved Oligomeric Golgi complex 861.0 0 0 0 0 0.7370871060633712 Q06096 0.932735025882721 0.955805003643036 0.9587849974632264 0.011996259912848473 0.1945286840200424 0.0 42.303251435791935 30.0 0.0 no 15576 chrXVI_741588r 37735 essential YPR107C 454 + TGACCGGATTTTGTCCTTTA T|153|S T|153|I silent|ACC>ACG|T|153 silent|ACC>ACT|T|153 YTH1 Yeast THirty kDa Homolog 208.0 0 0 0 0 0.28131886835429715 Q06102 0.15870903432369232 0.01179082039743662 49.359594741399796 40.0 0.0 no 15577 chrXVI_741806 37741 essential YPR107C 239 - ATTCATGTAAGTATTCACAT E|86|Q E|86|K YTH1 Yeast THirty kDa Homolog 208.0 0 0 0 0 -0.2751559960338774 Q06102 0.009238937869668009 0.00782521441578865 38.295520419400866 25.0 0.0 no 15578 chrXVI_742633r 37745 essential YPR108W 182 - CGCAAAGATATTTATAATAA C|67|S C|67|Y RPN7 Regulatory Particle Non-ATPase 429.0 0 0 0 0 0.5201024373507239 Q06103 0.562594473361969 1.0 30.680282558549038 20.0 1.0 no 15579 chrXVI_742678r 37746 essential YPR108W 227 - CATCGTGTTCCAAGTCAGAT D|82|H D|82|N RPN7 Regulatory Particle Non-ATPase 429.0 0 1 0 0 0.0218506293581659 Q06103 48.914971026334506 45.0 1.0 no 15580 chrXVI_742996 37754 essential YPR108W 542 + TAACGACCAACTTTATGTTA N|182|K silent|AAC>AAT|N|182 D|183|E silent|GAC>GAT|D|183 RPN7 Regulatory Particle Non-ATPase 429.0 0 0 0 0 0.4073950730138759 Q06103 0.6771728992462158 0.0 39.0291695070419 30.0 1.0 no 15581 chrXVI_743194 37757 essential YPR108W 740 + AAGCATTGCCACATATGCAT S|248|R silent|AGC>AGT|S|248 RPN7 Regulatory Particle Non-ATPase 429.0 0 0 0 0 0.32971195860655 Q06103 0.285681426525116 47.8161283589979 40.0 1.0 no 15582 chrXVI_743202r 37759 essential YPR108W 751 - ACCTGTGACCGATGCATATG G|257|R G|257|S G|257|A G|257|D RPN7 Regulatory Particle Non-ATPase 429.0 0 0 0 0 -1.4259615483182846 Q06103 0.008234730921685696 0.11254184693098067 0.022362589836120602 0.04982790723443031 49.8389063447554 50.0 1.0 no 15583 chrXVI_743215 37760 essential YPR108W 761 + GGTCACAGGTTTATTCACTC silent|GTC>GTG|V|255 silent|GTC>GTT|V|255 T|256|R T|256|I RPN7 Regulatory Particle Non-ATPase 429.0 0 0 0 0 0.1265370482052308 Q06103 0.027174733579158783 0.028683174401521683 49.455591101794035 45.0 1.0 no 15584 chrXVI_743248r 37761 essential YPR108W 797 - AATCGATGACTTTGGATTTT D|272|H D|272|N RPN7 Regulatory Particle Non-ATPase 429.0 0 0 0 0 -0.2653147161828576 Q06103 0.004368174821138382 0.013528803363442421 39.678425812160185 30.0 1.0 no 15585 chrXVI_743256r 37762 essential YPR108W 805 - TTCAGGTGAATCGATGACTT E|275|Q E|275|K RPN7 Regulatory Particle Non-ATPase 429.0 0 0 0 0 1.0784225715663944 Q06103 0.0 0.0 43.601554304718555 40.0 1.0 no 15586 chrXVI_743338r 37764 essential YPR108W 887 - TGGCATAATCGGACGCGTAA A|302|P A|302|T RPN7 Regulatory Particle Non-ATPase 429.0 0 0 0 0 0.7065943044077264 Q06103 0.27575796842575073 0.5644154548645021 47.01444399847088 50.0 1.0 no 15587 chrXVI_746060 37766 essential YPR110C 756 - TCAATACCAATAACACCTGG D|259|H D|259|N G|257|A G|257|D RPC40 RNA Polymerase C 335.0 0 0 0 0 -0.5174452819406591 P07703 0.0452236644923687 0.3377706706523895 0.3358209133148193 0.5474926233291626 0.18693999946117398 -0.04713999852538109 0.3109000027179718 0.4973399937152863 41.9935418879582 40.0 0.0 no 15588 chrXVI_746075r 37767 essential YPR110C 738 + TTTCAAAAATGTTTTCCCCC Q|248|E Q|248|* RPC40 RNA Polymerase C 335.0 0 0 0 0 -0.7947551972097178 P07703 1.0 2.0382800102233887 45.51496787168571 35.0 0.0 no 15589 chrXVI_746222 37769 essential YPR110C 594 - TTCAACGAAATTTCTTGACC L|204|F silent|TTG>TTA|L|204 silent|TCG>TCC|S|203 silent|TCG>TCA|S|203 RPC40 RNA Polymerase C 335.0 0 0 0 0 0.7277765205903153 P07703 0.055824797600507736 6.926720142364503 0.2171999961137772 39.629052514050606 35.0 0.0 no 15590 chrXVI_746453 37772 essential YPR110C 363 - TCCGTAAACTTTTCATCGTC silent|ACG>ACC|T|127 silent|ACG>ACA|T|127 D|128|H D|128|N RPC40 RNA Polymerase C 335.0 0 0 0 1 -0.2770727538746999 P07703 0.004253528080880642 0.012860871851444244 -0.1728000044822693 0.014360000379383562 45.254180983451825 40.0 0.0 no 15591 chrXVI_746490r 37773 essential YPR110C 323 + TGACCCTGATATGCTCACAT D|109|E silent|GAC>GAT|D|109 P|110|A P|110|S RPC40 RNA Polymerase C 335.0 0 0 0 0 0.4978262080226889 P07703 0.021479126065969467 0.28055480122566223 0.07519297301769258 -0.2965399920940399 2.755579948425293 3.540940046310425 50.39907973083848 45.0 0.0 no 15592 chrXVI_746588 37774 essential YPR110C 228 - ACGTATTCAGCAGCCACGGA V|83|L V|83|I RPC40 RNA Polymerase C 335.0 0 0 0 0 0.6046058770232723 P07703 0.0 0.0 0.20635999739170074 -0.9707199931144714 0.17900000512599945 -0.7868599891662598 54.205608318210686 55.00000000000001 0.0 no 15593 chrXVI_746613r 37776 essential YPR110C 200 + TCGTCGTATAATGATTTCCG R|68|G R|68|C R|69|G R|69|C RPC40 RNA Polymerase C 335.0 0 0 0 0 0.5478371759584065 P07703 0.0 0.0 0.0 0.0 2.0276200771331787 0.9283000230789183 1.3126800060272217 0.8939999938011169 2.023184061050415 0.925611972808838 0.8041365742683411 1.320159912109375 43.89815314299875 40.0 0.0 no 15594 chrXVI_746682r 37777 essential YPR110C 131 + TTCGTCATTAGACGCAAGAG S|45|W S|45|L S|46|* S|46|L RPC40 RNA Polymerase C 335.0 0 0 0 0 -1.4158411909955166 P07703 0.03718840703368187 0.363741010427475 0.2558666467666626 -0.8160799741744995 -1.2646199464797974 -0.2651599943637848 -1.04721999168396 -1.401877999305725 -0.23127134144306186 43.96704363555807 45.0 0.0 no 15595 chrXVI_746771r 37779 essential YPR110C 42 + ACAACCTCCACGGATTTTCC T|15|R T|15|I T|16|S T|16|I RPC40 RNA Polymerase C 335.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.12467544678815645 P07703 0.008049906231462955 0.3281489014625549 0.9708992838859558 0.19304987788200376 52.02971270506981 50.0 0.0 no 15596 chrXVI_749990r 37780 essential YPR112C 1907 + TGACTTAATGGAAGCAAACA D|637|E silent|GAC>GAT|D|637 MRD1 Multiple RNA-binding domain 887.0 0 0 0 0 -2.109618380106556 Q06106 0.9532920122146606 1.0 37.38410681294158 35.0 0.0 yes 15597 chrXVI_750001 37781 essential YPR112C 1899 - TCCATTAAGTCATTTGATGA M|639|I M|639|I E|640|Q E|640|K MRD1 Multiple RNA-binding domain 887.0 0 0 0 0 -0.6828234750502543 Q06106 0.9553959965705872 0.9553959965705872 0.956179976463318 0.9475290179252625 0.3630937337875366 0.3630937337875366 0.5868244171142578 0.922845721244812 41.31998717265736 30.0 0.0 no 15598 chrXVI_750002r 37782 essential YPR112C 1895 + ACCTTCATCAAATGACTTAA P|633|R P|633|L P|633|A P|633|S MRD1 Multiple RNA-binding domain 887.0 0 0 0 0 0.297587111282246 Q06106 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.6009654402732849 0.4567796289920807 0.8733124732971191 0.8288593292236328 39.127352788858616 30.0 0.0 no 15599 chrXVI_750238 37786 essential YPR112C 1662 - AATCTTTCCAATTTACCATA R|560|T R|560|K MRD1 Multiple RNA-binding domain 887.0 0 1 0 0 0.028925393549240005 Q06106 0.932735025882721 0.955805003643036 0.020097488537430763 0.4955177307128906 40.82695385115943 25.0 0.0 no 15600 chrXVI_750253r 37787 essential YPR112C 1644 + GGCGAAATGTTTTTGCCATA silent|GGC>GGG|G|549 silent|GGC>GGT|G|549 MRD1 Multiple RNA-binding domain 887.0 0 0 0 0 0.3880870177948634 Q06106 46.34781321470098 40.0 0.0 no 15601 chrXVI_750280 37788 essential YPR112C 1620 - TCTTCTCTAGTTGTCCCAAA E|547|Q E|547|K E|546|Q E|546|K MRD1 Multiple RNA-binding domain 887.0 0 0 0 0 0.2848438213647718 Q06106 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.0 0.0 0.06989651918411255 0.0558430515229702 49.86392225650616 40.0 0.0 no 15602 chrXVI_750398 37789 essential YPR112C 1502 - TTCTAACATCACCAATAACA R|507|T R|507|K V|506|L V|506|I MRD1 Multiple RNA-binding domain 887.0 0 0 0 0 -0.060282391777982336 Q06106 0.932735025882721 0.955805003643036 0.9539830088615416 0.9574310183525084 0.020235370844602585 1.0 0.15443235635757446 0.2319854199886322 38.49055153045407 30.0 0.0 no 15603 chrXVI_750506 37791 essential YPR112C 1394 - CACTACCCAAAACAGCATCT S|471|T S|471|N G|470|A G|470|D MRD1 Multiple RNA-binding domain 887.0 0 0 0 0 -0.4243444706100916 Q06106 0.9512869715690612 0.9536849856376648 0.9499930143356324 0.9446240067481996 0.34434810280799866 0.020639853551983837 0.7572249770164491 0.6183099150657654 46.53122884487192 45.0 0.0 no 15604 chrXVI_750519 37792 essential YPR112C 1381 - AGCATCTTGGTTCATATACA A|467|P A|467|T D|466|H D|466|N MRD1 Multiple RNA-binding domain 887.0 0 0 0 0 -0.19396568439113426 Q06106 0.9573720097541808 0.9523990154266356 0.9486550092697144 0.956179976463318 0.0 0.0 0.0 0.0 45.484586512615344 35.0 0.0 no 15605 chrXVI_750546r 37793 essential YPR112C 1351 + CATCCAGACAAACATTTTCT S|452|C S|452|F silent|TCC>TCG|S|452 silent|TCC>TCT|S|452 MRD1 Multiple RNA-binding domain 887.0 0 0 0 0 0.4683723027563294 Q06106 0.945252001285553 0.9294660091400146 0.03528280183672905 0.02565077506005764 42.099534872690526 35.0 0.0 no 15606 chrXVI_750620 37794 essential YPR112C 1280 - AATCAAACTCATCTAATCTA D|433|H D|433|N MRD1 Multiple RNA-binding domain 887.0 0 0 0 0 -1.2866584630969586 Q06106 0.9486550092697144 0.956179976463318 0.0938623994588852 0.3493499457836151 34.84575957274768 25.0 0.0 no 15607 chrXVI_750759 37795 essential YPR112C 1141 - TCCTTTGGATTGACCAGTCC G|387|R G|387|R G|387|A G|387|E MRD1 Multiple RNA-binding domain 887.0 0 0 0 0 -0.9548509383025228 Q06106 0.941340982913971 0.941340982913971 0.9499930143356324 0.9438679814338684 0.0 0.0 0.0 0.0 54.64694069838487 50.0 0.0 no 15608 chrXVI_750760r 37796 essential YPR112C 1137 + ACCAGGACTGGTCAATCCAA silent|ACC>ACG|T|380 silent|ACC>ACT|T|380 T|380|S T|380|I MRD1 Multiple RNA-binding domain 887.0 0 0 0 0 -0.2627800056097973 Q06106 0.9491789937019348 0.9472420215606691 0.5538022518157959 0.062369652092456825 50.83349402137742 50.0 0.0 no 15609 chrXVI_750777r 37797 essential YPR112C 1120 + TTCATGTGGCTTTGGATACC H|375|D H|375|Y MRD1 Multiple RNA-binding domain 887.0 0 0 0 0 0.2378337204891079 Q06106 0.9473130106925964 0.9489949941635132 0.0 0.0 50.18567902650881 45.0 0.0 no 15610 chrXVI_750834 37799 essential YPR112C 1066 - CCTGAAATCTTCTTCTTTGG R|362|T R|362|K MRD1 Multiple RNA-binding domain 887.0 0 0 0 0 0.05393687379777935 Q06106 0.932735025882721 0.955805003643036 0.03663504496216774 0.3150786757469177 44.88630567998104 40.0 0.0 no 15611 chrXVI_750945 37801 essential YPR112C 955 - TTCTGGTTGTTCTTCCTTCT E|325|Q E|325|K MRD1 Multiple RNA-binding domain 887.0 0 0 0 0 0.03828145224096705 Q06106 0.956179976463318 0.9475290179252625 0.5691395401954651 0.8878759741783142 54.111262986035115 40.0 0.0 no 15612 chrXVI_751079r 37802 essential YPR112C 818 + AAACCTCGCCCAAGATGAAA N|274|K silent|AAC>AAT|N|274 L|275|V L|275|F MRD1 Multiple RNA-binding domain 887.0 0 0 0 0 -0.30187687052626144 Q06106 0.9439849853515624 0.9512209892272948 0.9587849974632264 0.975437343120575 0.5792261362075806 0.1455749273300171 44.98431688045128 45.0 0.0 no 15613 chrXVI_751185 37804 essential YPR112C 715 - TATCATCTTTTCTTCCTCTC M|244|I M|244|I K|243|N silent|AAG>AAA|K|243 MRD1 Multiple RNA-binding domain 887.0 0 0 0 0 0.14494292753898289 Q06106 0.9553959965705872 0.9553959965705872 0.9355990290641784 0.21495090425014496 0.21495090425014496 0.5046314597129822 48.45584576759671 35.0 0.0 no 15614 chrXVI_751226r 37805 essential YPR112C 671 + TTCGGCTCTCAACAGAAACA S|225|W S|225|L A|226|G A|226|V MRD1 Multiple RNA-binding domain 887.0 1 Series([], Name: modification, dtype: object) 0 0 0 -2.4074470308010145 Q06106 0.9288619756698608 0.9298099875450134 0.9484469890594482 0.9504740238189696 0.01574027165770531 0.2551456689834595 0.19202551245689392 0.1663830280303955 44.87698130167695 45.0 0.0 yes 15615 chrXVI_751227r 37806 essential YPR112C 670 + ATTCGGCTCTCAACAGAAAC S|225|W S|225|L A|226|G A|226|V MRD1 Multiple RNA-binding domain 887.0 1 Series([], Name: modification, dtype: object) 0 0 0 1.3131845026084337 Q06106 0.9288619756698608 0.9298099875450134 0.9484469890594482 0.9504740238189696 0.01574027165770531 0.2551456689834595 0.19202551245689392 0.1663830280303955 43.623236721366816 45.0 0.0 no 15616 chrXVI_751264 37807 essential YPR112C 636 - TCATTCTCAATGACCAAATT E|219|Q E|219|K E|217|D silent|GAG>GAA|E|217 MRD1 Multiple RNA-binding domain 887.0 0 1 0 0 0.4409362489917065 Q06106 0.956179976463318 0.9475290179252625 0.94931298494339 0.09572245180606842 0.18622232973575592 0.1689520627260208 39.64966567427132 30.0 0.0 no 15617 chrXVI_751310r 37808 essential YPR112C 587 + GGCTCATGCATTAGCCTTAA A|197|G A|197|V H|198|D H|198|Y MRD1 Multiple RNA-binding domain 887.0 0 0 0 0 -0.6054509897819637 Q06106 0.9484469890594482 0.9504740238189696 0.9473130106925964 0.9489949941635132 51.6637933648754 45.0 0.0 no 15618 chrXVI_751418r 37811 essential YPR112C 479 + AAGCTCACAAGTCACATCAT S|161|R silent|AGC>AGT|S|161 S|162|* S|162|L MRD1 Multiple RNA-binding domain 887.0 0 0 0 0 0.0922798322020653 Q06106 0.9417110085487366 0.9298099875450134 0.2490745186805725 0.25004351139068604 44.701314571744774 40.0 0.0 no 15619 chrXVI_751629 37817 essential YPR112C 271 - GTCTGCAAAGCTTTTAGCCA D|97|H D|97|N A|96|P A|96|T MRD1 Multiple RNA-binding domain 887.0 0 0 0 0 0.14352554318011185 Q06106 0.9486550092697144 0.956179976463318 0.9573720097541808 0.9523990154266356 0.014621091075241566 0.058664672076702125 0.2714857757091522 0.3792748749256134 51.19827633181932 45.0 0.0 no 15620 chrXVI_751804r 37820 essential YPR112C 93 + CATCAAGCAGTTAATGGTAG Q|33|E Q|33|* MRD1 Multiple RNA-binding domain 887.0 0 0 0 0 0.05252595733614232 Q06106 0.9590039849281312 41.46506288726232 40.0 0.0 no 15621 chrXVI_751805 37821 essential YPR112C 95 - CACTACCATTAACTGCTTGA S|38|T S|38|N G|37|A G|37|D MRD1 Multiple RNA-binding domain 887.0 0 0 0 0 -0.41155265409154623 Q06106 0.9512869715690612 0.9536849856376648 0.9499930143356324 0.9446240067481996 45.20989082204596 40.0 0.0 no 15622 chrXVI_751806 37822 essential YPR112C 94 - ACTACCATTAACTGCTTGAT S|38|T S|38|N G|37|A G|37|D MRD1 Multiple RNA-binding domain 887.0 0 0 0 0 -0.09768794604575308 Q06106 0.9512869715690612 0.9536849856376648 0.9499930143356324 0.9446240067481996 43.93432786535783 35.0 0.0 no 15623 chrXVI_751862r 37823 essential YPR112C 35 + TCTAACAGATGATAATCTCA L|13|V silent|CTA>TTA|L|13 T|14|R T|14|I MRD1 Multiple RNA-binding domain 887.0 0 0 0 0 0.8297548509896935 Q06106 0.9512209892272948 0.9476869702339172 0.9472420215606691 0.7748382687568665 0.0381607785820961 0.034787870943546295 37.21229231891419 30.0 0.0 no 15624 chrXVI_752262 37826 essential YPR113W 5 + TTCGAATTCAACACCAGAAA S|3|W S|3|L PIS1 Phosphatidyl Inositol Synthase 220.0 0 0 0 0 0.2957826407071225 P06197 0.9288619756698608 0.9298099875450134 38.75969085054686 35.0 1.0 no 15625 chrXVI_752380r 37829 essential YPR113W 126 - TACAACCATGTAAAGGCCGT L|48|F silent|TTG>TTA|L|48 W|47|C W|47|* PIS1 Phosphatidyl Inositol Synthase 220.0 0 0 0 0 -0.4689562717909367 P06197 0.9587849974632264 0.8858469724655151 0.1593802124261856 0.0945066437125206 46.89715622351861 45.0 1.0 no 15626 chrXVI_752375 37830 essential YPR113W 118 + ATCATCCTACGGCCTTTACA H|41|D H|41|Y P|42|A P|42|S PIS1 Phosphatidyl Inositol Synthase 220.0 0 0 0 0 -0.25255075660021203 P06197 0.9473130106925964 0.9489949941635132 0.9562489986419678 0.9498909711837769 0.023834662511944767 0.07202091068029404 0.0 0.0 52.48617022575003 45.0 1.0 no 15627 chrXVI_752413 37831 essential YPR113W 156 + TGTCTACTGGATGCGCTAGA L|54|V silent|CTA>TTA|L|54 L|55|V silent|CTG>TTG|L|55 PIS1 Phosphatidyl Inositol Synthase 220.0 0 0 0 0 0.8303781488193998 P06197 0.9512209892272948 0.9512209892272948 0.0827169343829155 0.0 51.068064421848995 50.0 1.0 no 15628 chrXVI_752452 37833 essential YPR113W 195 + TACAATCAGGTTTCCAGTCT Y|66|* silent|TAC>TAT|Y|66 Q|68|E Q|68|* PIS1 Phosphatidyl Inositol Synthase 220.0 0 0 0 0 -1.14646549002381 P06197 0.9590039849281312 0.0 48.469613499442175 40.0 1.0 no 15629 chrXVI_752495r 37837 essential YPR113W 241 - GCCAGCGGTACTGGATCTGT G|87|R G|87|S G|87|A G|87|D PIS1 Phosphatidyl Inositol Synthase 220.0 0 0 0 0 -1.6789798054856706 P06197 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.025784915313124657 0.6637522578239441 0.4802694022655487 0.03020639158785343 58.840455748248864 60.0 1.0 no 15630 chrXVI_752477r 37839 essential YPR113W 223 - GTCGGTAACCATGTCCAGAA D|81|H D|81|N PIS1 Phosphatidyl Inositol Synthase 220.0 0 0 0 0 -6.085733309174825 P06197 0.9486550092697144 0.956179976463318 0.0 0.0 50.61138627555045 50.0 1.0 yes 15631 chrXVI_752562 37840 essential YPR113W 305 + CTTCCAATTAATGCTGGGCT F|103|L silent|TTC>TTT|F|103 Q|104|E Q|104|* PIS1 Phosphatidyl Inositol Synthase 220.0 0 0 0 0 0.5894208322102807 P06197 0.9387490153312684 0.9590039849281312 0.20046685636043549 0.010643359273672104 49.65481956385457 45.0 1.0 no 15632 chrXVI_752615r 37841 essential YPR113W 361 - AGTCTTACCAGCACTTAAAC K|126|N silent|AAG>AAA|K|126 PIS1 Phosphatidyl Inositol Synthase 220.0 0 0 0 0 0.1012430837243607 P06197 0.9355990290641784 0.22737163305282596 44.3293182635141 40.0 1.0 no 15633 chrXVI_752679r 37844 essential YPR113W 425 - CGTCTCTTCTCGTGTAGTAC D|148|H D|148|N R|147|T R|147|K PIS1 Phosphatidyl Inositol Synthase 220.0 0 0 0 0 0.5337088558247457 P06197 0.9486550092697144 0.956179976463318 0.932735025882721 0.955805003643036 0.1262110471725464 0.5007416605949402 0.21951375901699066 0.5306288599967957 51.42702405251771 50.0 1.0 no 15634 chrXVI_796535r 37848 essential YPR133C 653 + TCAAAGTGTCAGAATATGGT Q|219|E Q|219|* SPN1 Suppresses Postrecruitment functions gene Number 1 410.0 0 0 0 0 0.4903236393293327 Q06505 0.9590039849281312 1.0 -0.27257999777793884 39.89751636663016 35.0 0.0 no 15635 chrXVI_796571r 37850 essential YPR133C 617 + AAACTTGGCAGACACCATTT N|207|K silent|AAC>AAT|N|207 SPN1 Suppresses Postrecruitment functions gene Number 1 410.0 0 0 0 0 0.19274980005271167 Q06505 0.9439849853515624 0.09647650271654128 -0.6686800122261047 45.18119100171123 40.0 0.0 no 15636 chrXVI_796623 37853 essential YPR133C 568 - CAACAATTTGACCTTCTGCA L|195|F silent|TTG>TTA|L|195 SPN1 Suppresses Postrecruitment functions gene Number 1 410.0 0 0 0 0 0.3627422072537555 Q06505 0.9587849974632264 0.022023862227797508 1.8188400268554688 2.4632399082183842 45.07989372375046 40.0 0.0 no 15637 chrXVI_796828 37857 essential YPR133C 363 - TCCAATTCCTGTCTACTACT L|127|F silent|TTG>TTA|L|127 E|128|Q E|128|K SPN1 Suppresses Postrecruitment functions gene Number 1 410.0 0 1 0 0 -2.8913882309966112 Q06505 0.9587849974632264 0.956179976463318 0.9475290179252625 0.3184784054756165 0.0 0.0 49.60254848089818 40.0 0.0 yes 15638 chrXVI_796881r 37860 essential YPR133C 307 + TTCAACCAACGGTGGAAAAT Q|104|E Q|104|* P|105|A P|105|S SPN1 Suppresses Postrecruitment functions gene Number 1 410.0 0 1 0 0 -0.2354688310581464 Q06505 0.9590039849281312 0.9562489986419678 0.9498909711837769 1.0 0.8224886059761047 0.7530940175056458 40.59963650314768 40.0 0.0 no 15639 chrXVI_797020 37862 essential YPR133C 171 - TCGTTCTTTTCTCCGTTATC E|64|Q E|64|K K|62|N silent|AAG>AAA|K|62 SPN1 Suppresses Postrecruitment functions gene Number 1 410.0 0 0 0 0 0.237013347127268 Q06505 0.956179976463318 0.9475290179252625 0.9355990290641784 0.4511270523071289 0.6746653318405151 0.3485462963581085 50.16916164988066 40.0 0.0 no 15640 chrXVI_797037 37863 essential YPR133C 154 - ATCTGGGTCTTTAGTATCAT D|58|H D|58|N SPN1 Suppresses Postrecruitment functions gene Number 1 410.0 0 0 0 0 -1.40537807415326 Q06505 0.9486550092697144 0.956179976463318 0.026104113087058067 0.13253243267536166 46.64479300018058 35.0 0.0 no 15641 chrXVI_797121 37864 essential YPR133C 70 - AGCGTTTATAGTTGACTTTT A|30|P A|30|T SPN1 Suppresses Postrecruitment functions gene Number 1 410.0 0 1 0 0 -0.9261999204166016 Q06505 0.9573720097541808 0.9523990154266356 43.135616631562975 30.0 0.0 no 15642 chrXVI_797120 37865 essential YPR133C 71 - CAGCGTTTATAGTTGACTTT A|30|P A|30|T SPN1 Suppresses Postrecruitment functions gene Number 1 410.0 0 1 0 0 0.260729700435098 Q06505 0.9573720097541808 0.9523990154266356 44.24271393709961 35.0 0.0 no 15643 chrXVI_799253 37867 high_effect YPR135W 19 + AGCTTGTTTTTGACTTTGGT L|8|V L|8|F CTF4 Chromosome Transmission Fidelity 927.0 0 0 0 0 0.6757692705346787 Q01454 0.3099287748336792 0.09691882878541946 47.73436655948905 35.0 1.0 no 15644 chrXVI_799263 37868 high_effect YPR135W 29 + TGACTTTGGTGGGAAAACTC D|11|E silent|GAC>GAT|D|11 CTF4 Chromosome Transmission Fidelity 927.0 0 0 0 0 0.10381613723918556 Q01454 0.7205569744110107 42.86780659925995 45.0 1.0 no 15645 chrXVI_799435 37869 high_effect YPR135W 201 + TTTCTGATGACTACAATGCA L|69|V silent|CTG>TTG|L|69 CTF4 Chromosome Transmission Fidelity 927.0 0 0 0 0 -1.0118528827098274 Q01454 1.0 41.888976228261704 35.0 1.0 no 15646 chrXVI_799528 37870 high_effect YPR135W 294 + GACTGCTGTGTTATTCATTC D|99|E silent|GAC>GAT|D|99 C|100|W silent|TGC>TGT|C|100 CTF4 Chromosome Transmission Fidelity 927.0 0 0 0 0 -0.07122549263645025 Q01454 0.13839535415172574 0.024948785081505772 46.90705223215781 40.0 1.0 no 15647 chrXVI_799590r 37872 high_effect YPR135W 359 - TTTCATCGTCCAATTCCAAA E|126|Q E|126|K D|125|H D|125|N CTF4 Chromosome Transmission Fidelity 927.0 0 0 0 0 0.3799757670363033 Q01454 0.5506185293197632 0.8590681552886963 0.06617230921983719 0.7167525887489319 44.73777987526074 35.0 1.0 no 15648 chrXVI_799628r 37873 high_effect YPR135W 397 - AACTTGTTCATCGATTTTAA V|139|L V|139|I CTF4 Chromosome Transmission Fidelity 927.0 0 0 0 0 -0.209353982861026 Q01454 0.19532297551631927 0.09863732755184174 37.62704467092942 25.0 1.0 no 15649 chrXVI_799876r 37874 high_effect YPR135W 645 - TCAGCTACATTGTTCTCATC D|222|H D|222|N A|221|P A|221|T CTF4 Chromosome Transmission Fidelity 927.0 0 0 0 0 1.3728453635218305 Q01454 0.037107057869434364 0.19056960940361026 0.2770457863807678 0.5759282112121582 47.6837027961048 40.0 1.0 no 15650 chrXVI_800037 37876 high_effect YPR135W 803 + CACAAATCTCTCATCAACAA T|269|R T|269|I CTF4 Chromosome Transmission Fidelity 927.0 0 0 0 0 -0.3238014315137197 Q01454 0.465579092502594 0.476699024438858 38.53802353086439 35.0 1.0 no 15651 chrXVI_800074 37877 high_effect YPR135W 840 + TTGCAATTTGACCCGTTACG Q|282|E Q|282|* CTF4 Chromosome Transmission Fidelity 927.0 0 0 0 0 0.9562404851870828 Q01454 1.0 47.58207933075693 45.0 1.0 no 15652 chrXVI_800086r 37878 high_effect YPR135W 855 - GCAATGTAAGTTCCACGTAA A|292|P A|292|T CTF4 Chromosome Transmission Fidelity 927.0 0 0 0 0 -0.25619408718833464 Q01454 0.0 0.0 44.23607940544787 40.0 1.0 no 15653 chrXVI_800153 37879 high_effect YPR135W 919 + CTTCCGAGATCCACTACACC S|308|C S|308|F silent|TCC>TCG|S|308 silent|TCC>TCT|S|308 CTF4 Chromosome Transmission Fidelity 927.0 0 0 0 0 0.5968646313361359 Q01454 0.06635549664497375 0.08707217127084732 53.31277687771582 55.00000000000001 1.0 no 15654 chrXVI_800270r 37880 high_effect YPR135W 1039 - CTCTGCCAAATTTTGGACAA E|353|Q E|353|K A|352|P A|352|T CTF4 Chromosome Transmission Fidelity 927.0 0 0 0 0 0.7833290529386704 Q01454 0.22009319067001346 0.3877657651901245 0.1282328963279724 0.1761636883020401 44.246554729233644 40.0 1.0 no 15655 chrXVI_800481r 37884 high_effect YPR135W 1250 - TCTTTTCACTTAATCCACTG K|423|N silent|AAG>AAA|K|423 E|422|Q E|422|K CTF4 Chromosome Transmission Fidelity 927.0 0 0 0 0 -0.08136042310325227 Q01454 0.3637429475784302 0.3901966512203217 0.5787205696105957 43.94942180945913 35.0 1.0 no 15656 chrXVI_800483r 37885 high_effect YPR135W 1252 - TCTCTTTTCACTTAATCCAC K|423|N silent|AAG>AAA|K|423 R|424|T R|424|K CTF4 Chromosome Transmission Fidelity 927.0 0 0 0 0 -0.4620388312167962 Q01454 0.3637429475784302 0.513744056224823 1.0 44.96364490458552 35.0 1.0 no 15657 chrXVI_800482r 37886 high_effect YPR135W 1251 - CTCTTTTCACTTAATCCACT K|423|N silent|AAG>AAA|K|423 CTF4 Chromosome Transmission Fidelity 927.0 0 0 0 0 -0.035514150430933485 Q01454 0.3637429475784302 45.803884884543784 35.0 1.0 no 15658 chrXVI_800277r 37888 high_effect YPR135W 1046 - CTACGGACTCTGCCAAATTT V|355|L V|355|I CTF4 Chromosome Transmission Fidelity 927.0 0 0 0 0 0.4130422026816473 Q01454 0.3064934611320496 0.18961836397647855 46.9347727628579 45.0 1.0 no 15659 chrXVI_800626r 37889 high_effect YPR135W 1395 - CCTGTGTTTGCCAAACTGAT G|472|R G|472|R CTF4 Chromosome Transmission Fidelity 927.0 0 0 0 0 0.1076058421835672 Q01454 0.6666141748428345 0.6666141748428345 49.45209785565743 45.0 1.0 no 15660 chrXVI_800616 37890 high_effect YPR135W 1382 + TCATTCGTTTCCAATCAGTT H|462|D H|462|Y S|463|W S|463|L CTF4 Chromosome Transmission Fidelity 927.0 0 1 0 0 0.036580028687436816 Q01454 0.641989529132843 0.4260120987892151 0.020317533984780308 0.2979230880737305 46.855060992682134 35.0 1.0 no 15661 chrXVI_800671 37891 high_effect YPR135W 1437 + TCTCCAGCGGGAACACCTTT P|481|A P|481|S S|480|C S|480|F CTF4 Chromosome Transmission Fidelity 927.0 0 0 0 0 -0.5402730674205609 Q01454 0.8057671785354614 0.9173896312713624 0.0 0.0 2.259926080703736 2.533777952194214 1.4354660511016846 12.247659683227539 55.4829696503159 55.00000000000001 1.0 no 15662 chrXVI_800944r 37894 high_effect YPR135W 1713 - ATTCTCTCACCAGCTTGCAA R|577|T R|577|K E|576|D silent|GAG>GAA|E|576 CTF4 Chromosome Transmission Fidelity 927.0 0 0 0 0 0.1808727365636036 Q01454 0.18405550718307492 1.0 0.0 0.09855400025844574 0.07833799719810486 4.2548418045043945 52.433024818793285 45.0 1.0 no 15663 chrXVI_800986r 37898 high_effect YPR135W 1755 - GTACCAACAATAACGCGAAC G|591|A G|591|D G|591|R G|591|S CTF4 Chromosome Transmission Fidelity 927.0 0 0 0 0 -0.887960874396633 Q01454 1.0 0.090523861348629 0.07303942739963531 0.4926835596561432 2.153402090072632 6.840740203857423 15.322896003723145 3.8601279258728023 40.799097693528154 45.0 1.0 no 15664 chrXVI_801023 37899 high_effect YPR135W 1789 + TCAGAAGTTTCAATCAATTC F|597|L silent|TTC>TTT|F|597 CTF4 Chromosome Transmission Fidelity 927.0 0 0 0 0 0.2494470433947697 Q01454 0.596396267414093 0.8885639905929565 36.99784463912785 30.0 1.0 no 15665 chrXVI_801072r 37901 high_effect YPR135W 1841 - GAGCAGTAAGCGCTACAATT A|620|P A|620|T CTF4 Chromosome Transmission Fidelity 927.0 0 0 0 0 -1.7629414991326762 Q01454 0.04441006854176521 0.4296885132789612 3.8792319297790527 1.5148199796676636 46.286245416883794 45.0 1.0 no 15666 chrXVI_801083 37902 high_effect YPR135W 1849 + CGCTTACTGCTCAGAATTAT L|618|V L|618|F T|619|S T|619|I CTF4 Chromosome Transmission Fidelity 927.0 0 0 0 0 0.2542729184290479 Q01454 0.5861687660217285 0.25063225626945496 0.3702254295349121 0.09509019553661346 1.231786012649536 2.5449960231781006 0.3615880012512207 -0.9402899742126464 45.09896978129029 40.0 1.0 no 15667 chrXVI_801115 37903 high_effect YPR135W 1881 + GTACATTATTCGCAGTTTCA H|629|D H|629|Y CTF4 Chromosome Transmission Fidelity 927.0 0 0 0 0 0.13950266576946774 Q01454 0.4868036508560181 0.13432636857032776 4.213531970977783 -0.04603200033307076 45.54411013641141 35.0 1.0 no 15668 chrXVI_801142 37904 high_effect YPR135W 1908 + TCATACTCTTTATCTGAATT S|637|* S|637|L Y|638|* silent|TAC>TAT|Y|638 CTF4 Chromosome Transmission Fidelity 927.0 0 0 0 0 0.40832296552485786 Q01454 0.09455226361751556 -1.9205360412597656 -2.1747000217437744 38.53270672963345 25.0 1.0 no 15669 chrXVI_801217r 37905 high_effect YPR135W 1986 - TTCATATCAGAATTAATGTT M|668|I M|668|I CTF4 Chromosome Transmission Fidelity 927.0 0 0 0 0 -0.09490934756677448 Q01454 0.2846260666847229 0.2846260666847229 34.174838794006746 20.0 1.0 no 15670 chrXVI_801258 37906 high_effect YPR135W 2024 + CTACTACAATTTTAATCCGA Y|676|* silent|TAC>TAT|Y|676 Y|677|* silent|TAC>TAT|Y|677 CTF4 Chromosome Transmission Fidelity 927.0 0 0 0 0 0.7280984223152644 Q01454 38.88220895744837 30.0 1.0 no 15671 chrXVI_801274r 37908 high_effect YPR135W 2043 - AACAAACTTTTGATGCCCAT L|687|F silent|TTG>TTA|L|687 S|686|T S|686|N CTF4 Chromosome Transmission Fidelity 927.0 0 0 0 0 -0.7700061317869145 Q01454 0.18398575484752652 0.30651751160621643 0.9851455688476562 14.405234336853027 0.0613740012049675 -1.7406799793243408 43.43118374832461 35.0 1.0 no 15672 chrXVI_802373r 37910 essential YPR137W 17 - ATCTTTTCCTCTTTTTCTGT R|12|T R|12|K RRP9 Ribosomal RNA Processing 573.0 0 0 0 0 0.668441860666572 Q06506 0.1958831697702408 0.4699511826038361 49.08109818612337 30.0 1.0 no 15673 chrXVI_802413r 37911 essential YPR137W 57 - TCGTCTACTGTGGGTTTTGA E|26|Q E|26|K D|25|H D|25|N RRP9 Ribosomal RNA Processing 573.0 0 1 0 0 -1.985191451917493 Q06506 0.14984002709388733 0.22100865840911865 0.058613669127225876 0.22819024324417114 50.67831454332753 45.0 1.0 no 15674 chrXVI_802714r 37912 essential YPR137W 358 - AGCAACGTCTTCTTTTAACC A|126|P A|126|T V|125|L V|125|I RRP9 Ribosomal RNA Processing 573.0 0 0 0 0 0.08564930841466345 Q06506 0.03843974322080612 0.05178385227918625 0.02648942731320858 0.11714572459459305 45.774390801809766 40.0 1.0 no 15675 chrXVI_802790 37913 essential YPR137W 431 + AGCAAAACAGAGCTTTACCA A|145|G A|145|V RRP9 Ribosomal RNA Processing 573.0 0 0 0 0 0.47260704239563 Q06506 0.22204037010669708 0.25629934668540955 1.8098000288009644 -1.3976399898529053 1.559000015258789 0.4352000057697296 43.86139366995468 40.0 1.0 no 15676 chrXVI_802870r 37916 essential YPR137W 514 - GCCATTAGATGATTCCTCGA G|178|R G|178|S G|178|A G|178|D RRP9 Ribosomal RNA Processing 573.0 0 1 0 0 -0.7392753873381783 Q06506 50.39344693522236 45.0 1.0 no 15677 chrXVI_802884 37917 essential YPR137W 525 + TCTAATGGCGATAAGAACAA S|176|C S|176|F RRP9 Ribosomal RNA Processing 573.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.5179918909025295 Q06506 -0.2565999925136566 -1.7347999811172483 37.18618883039136 35.0 1.0 no 15678 chrXVI_802986 37918 essential YPR137W 627 + AAGCTAAAATACGCTAAAGG L|211|V silent|CTA>TTA|L|211 RRP9 Ribosomal RNA Processing 573.0 0 0 0 0 0.12130033704884514 Q06506 1.0 0.9609199762344359 0.9657999873161316 35.0129005306207 35.0 1.0 no 15679 chrXVI_803089r 37922 essential YPR137W 733 - AACATATTTACCATCTGGTG V|251|L V|251|I RRP9 Ribosomal RNA Processing 573.0 0 0 0 0 0.1210540380135045 Q06506 0.2862229645252228 0.18092158436775208 0.6010599732398987 1.15146005153656 42.21834337415311 35.0 1.0 no 15680 chrXVI_803178 37923 essential YPR137W 819 + ATTCCAACAAAGGATCGCCG P|275|A P|275|S P|275|R P|275|L RRP9 Ribosomal RNA Processing 573.0 0 0 0 0 -0.8541833837845026 Q06506 0.3640750050544739 0.3873281478881836 0.2322814613580704 0.13841910660266876 1.65201997756958 2.776400089263916 3.757980108261109 3.6678199768066406 47.045335758727724 50.0 1.0 no 15681 chrXVI_803195r 37925 essential YPR137W 839 - CCAACGATAAAACTTCCCCT L|286|F silent|TTG>TTA|L|286 silent|TCG>TCC|S|285 silent|TCG>TCA|S|285 RRP9 Ribosomal RNA Processing 573.0 0 1 0 0 -2.12190728528092 Q06506 0.021748688071966168 4.115580081939696 47.019347336923936 45.0 1.0 yes 15682 chrXVI_803296 37926 essential YPR137W 937 + CCCAGTTGGAGATTCTTTAT Q|314|E Q|314|* silent|TCC>TCG|S|313 silent|TCC>TCT|S|313 RRP9 Ribosomal RNA Processing 573.0 0 0 0 0 -0.09952672683978192 Q06506 0.6737531423568726 -0.36480000615119934 49.08263986031324 40.0 1.0 no 15683 chrXVI_803422r 37930 essential YPR137W 1066 - GCCACCTCTAAATGTTAGTC G|362|R G|362|S G|362|A G|362|D RRP9 Ribosomal RNA Processing 573.0 0 1 0 0 -1.0733526516698475 Q06506 0.0062547135166823855 0.02349136956036091 0.017999032512307167 0.10762889683246613 5.42303991317749 3.53764009475708 3.1569199562072754 5.940760135650635 49.208858419663954 45.0 1.0 no 15684 chrXVI_803451r 37932 essential YPR137W 1095 - CATCTCCTTAGTAGCTTTTG R|371|T R|371|K R|370|S silent|AGG>AGA|R|370 RRP9 Ribosomal RNA Processing 573.0 0 0 0 0 0.2896062641385666 Q06506 0.5713387131690979 0.9686267971992492 0.596005380153656 1.209480047225952 -0.15226000547409058 0.4434199929237366 0.3192000091075897 48.30568265566103 40.0 1.0 no 15685 chrXVI_803535 37933 essential YPR137W 1176 + GCACCTTTATTTTTCTGCGA P|394|A P|394|S A|393|G A|393|V RRP9 Ribosomal RNA Processing 573.0 0 0 0 0 0.413076826558824 Q06506 0.7780672311782837 0.7605592012405396 0.34988269209861755 0.2626323401927948 0.5297999978065491 0.06840000301599503 50.15826102192438 40.0 1.0 no 15686 chrXVI_818366r 37934 essential YPR143W 46 - CCCAAATTCTGCATTCTTTC G|22|R G|22|R G|22|A G|22|E RRP15 Ribosomal RNA Processing 250.0 0 0 0 0 -0.008607131721151129 Q06511 0.4344873428344727 0.4344873428344727 0.8463156819343567 1.0 47.692464557092244 40.0 1.0 no 15687 chrXVI_818412r 37935 essential YPR143W 92 - CCGGCTCATTACTTAACTCT silent|CCG>CCC|P|37 silent|CCG>CCA|P|37 E|36|D silent|GAG>GAA|E|36 RRP15 Ribosomal RNA Processing 250.0 0 0 0 0 -1.6492994855955303 Q06511 0.6288715004920961 49.54486847115118 45.0 1.0 no 15688 chrXVI_818465r 37938 essential YPR143W 145 - GCTATTCTGCTCGTCTTCTT S|55|T S|55|N Q|53|H silent|CAG>CAA|Q|53 RRP15 Ribosomal RNA Processing 250.0 1 Series([], Name: modification, dtype: object) 0 0 0 0.31959029560316143 Q06511 0.7190605401992798 0.5275373458862305 0.11580409854650495 54.373594891933976 45.0 1.0 no 15689 chrXVI_820227 37946 essential YPR144C 1177 - AATCACGGTGACAATAGCAG silent|GTG>GTC|V|398 silent|GTG>GTA|V|398 V|398|L V|398|M NOC4 NucleOlar Complex associated 552.0 0 0 0 0 0.2320950786462561 Q06512 0.9539830088615416 0.9587630033493042 0.0874183177947998 0.01626667194068432 42.66624206549176 45.0 0.0 no 15690 chrXVI_820337r 37950 essential YPR144C 1064 + AGCAAGATTTTTCAGGTTAA A|356|G A|356|V NOC4 NucleOlar Complex associated 552.0 0 1 0 0 0.0773420936232945 Q06512 0.9484469890594482 0.9504740238189696 0.03788864985108376 0.033090446144342416 40.394390991567995 30.0 0.0 no 15691 chrXVI_820535r 37955 essential YPR144C 866 + CCACACTCCAACTAAACTAA H|290|Q silent|CAC>CAT|H|290 H|290|D H|290|Y NOC4 NucleOlar Complex associated 552.0 0 0 0 0 -0.34715541380329185 Q06512 0.9588389992713928 0.9473130106925964 0.9489949941635132 0.5682327747344971 0.6196464896202087 0.07155071198940277 42.18635306779714 40.0 0.0 no 15692 chrXVI_820638 37957 essential YPR144C 766 - TAACCAATTTTTCTCGAAAT W|261|C W|261|* W|261|S W|261|* NOC4 NucleOlar Complex associated 552.0 0 0 0 0 0.5068398669351967 Q06512 0.8858469724655151 0.8858469724655151 0.03469932824373245 0.04657004401087761 36.396433253043256 25.0 0.0 no 15693 chrXVI_820672 37958 essential YPR144C 732 - GACTCGTTCTCTATGGCTTG E|250|D silent|GAG>GAA|E|250 E|250|Q E|250|K NOC4 NucleOlar Complex associated 552.0 0 0 0 0 0.23932405279867355 Q06512 0.94931298494339 0.956179976463318 0.9475290179252625 0.6080631613731384 0.6025302410125732 0.8779690861701965 51.204777158048046 50.0 0.0 no 15694 chrXVI_820774r 37961 essential YPR144C 627 + GACTTGCTTTTGAAAAACGT D|210|E silent|GAC>GAT|D|210 L|212|V L|212|F NOC4 NucleOlar Complex associated 552.0 0 0 0 0 0.6760879335498197 Q06512 0.9532920122146606 0.9512209892272948 0.9587849974632264 1.0 0.3888750076293945 0.12370168417692184 39.067826173704255 35.0 0.0 no 15695 chrXVI_820782 37962 essential YPR144C 622 - TTTCAAAAGCAAGTCCTGGT L|213|F silent|TTG>TTA|L|213 NOC4 NucleOlar Complex associated 552.0 0 0 0 0 0.4603028638911241 Q06512 0.9587849974632264 0.7058660387992859 45.11637465996728 40.0 0.0 no 15696 chrXVI_820932 37965 essential YPR144C 472 - CTCTATTTCACCCATGTTCG E|164|Q E|164|K NOC4 NucleOlar Complex associated 552.0 0 0 0 0 0.6432618402237411 Q06512 0.956179976463318 0.9475290179252625 0.5947785377502441 0.9984754323959352 50.49688967680476 45.0 0.0 no 15697 chrXVI_820972 37966 essential YPR144C 432 - AACTTTCTGAATGTTTTATT K|150|N silent|AAG>AAA|K|150 R|149|T R|149|K NOC4 NucleOlar Complex associated 552.0 0 0 0 0 0.3837654614067652 Q06512 0.9355990290641784 0.932735025882721 0.955805003643036 0.5171597003936768 0.10787338763475418 1.0 35.92367553990823 20.0 0.0 no 15698 chrXVI_821009r 37967 essential YPR144C 392 + AACTCATTTTGCATCTGAAA T|132|S T|132|I H|133|D H|133|Y NOC4 NucleOlar Complex associated 552.0 0 0 0 0 0.4932439862911069 Q06512 0.9491789937019348 0.9472420215606691 0.9473130106925964 0.9489949941635132 0.8214221000671387 0.2278633266687393 0.15586495399475098 1.0 39.169785297549076 30.0 0.0 no 15699 chrXVI_821077r 37968 essential YPR144C 324 + ATACCTTTCGAAACATCACT P|110|A P|110|S P|110|R P|110|L NOC4 NucleOlar Complex associated 552.0 0 0 0 0 0.17074509099930907 Q06512 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.6259026527404785 0.5973424315452576 0.3784200847148895 0.2184326946735382 42.174168747234376 35.0 0.0 no 15700 chrXVI_821325 37972 essential YPR144C 79 - TTCATTGATTAACTTGATAA E|33|Q E|33|K NOC4 NucleOlar Complex associated 552.0 0 0 0 0 1.216110256196894 Q06512 0.956179976463318 0.9475290179252625 0.5061162114143372 0.6179112195968628 33.42496545406749 20.0 0.0 no 15701 chrXVI_864963 37976 essential YPR161C 1440 - CCGTATCTATTAACTCCTGC G|487|R G|487|R R|485|T R|485|K SGV1 Suppressor of Gpa1-Val50 mutation 657.0 0 0 0 0 -1.669059919054459 P23293 0.941340982913971 0.941340982913971 0.932735025882721 0.955805003643036 0.6264334917068481 0.6264334917068481 0.032510749995708466 0.3406291306018829 49.13743021657257 45.0 0.0 no 15702 chrXVI_864978r 37979 essential YPR161C 1422 + CCACCGCCAGCAGCCCCTGC P|476|A P|476|S P|475|R P|475|L SGV1 Suppressor of Gpa1-Val50 mutation 657.0 0 0 0 0 0.15615403220507598 P23293 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.7917980551719666 0.773991048336029 0.409219890832901 0.6638216972351074 71.53403680372531 80.0 0.0 no 15703 chrXVI_865020r 37980 essential YPR161C 1380 + AGACCGTATCATGTGAACAG P|462|A P|462|S P|462|R P|462|L SGV1 Suppressor of Gpa1-Val50 mutation 657.0 0 0 0 0 0.05078427894590039 P23293 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.7860680222511292 0.7547726631164551 0.5764241814613342 0.3576102554798126 44.30748440970689 45.0 0.0 no 15704 chrXVI_865059 37981 essential YPR161C 1344 - TCTCTTATTTTCGAAGGAGG R|454|T R|454|K E|455|Q E|455|K SGV1 Suppressor of Gpa1-Val50 mutation 657.0 0 0 0 0 0.5517871534380583 P23293 0.932735025882721 0.955805003643036 0.956179976463318 0.9475290179252625 0.5252630710601807 1.0 0.5486427545547485 0.913654327392578 43.32305476948778 40.0 0.0 no 15705 chrXVI_865122 37982 essential YPR161C 1281 - TCATCTTTCTTGGGGCCTCT D|434|H D|434|N D|433|H D|433|N SGV1 Suppressor of Gpa1-Val50 mutation 657.0 0 0 0 0 -0.4689266961662944 P23293 0.9486550092697144 0.956179976463318 0.9486550092697144 0.956179976463318 0.09677040576934813 0.32978764176368713 0.055795196443796165 0.15511979162693024 58.201396570853774 50.0 0.0 no 15706 chrXVI_865113 37984 essential YPR161C 1290 - AAACTTGCGTCATCTTTCTT S|436|T S|436|N SGV1 Suppressor of Gpa1-Val50 mutation 657.0 0 0 0 0 -0.026865736052094368 P23293 0.9512869715690612 0.9536849856376648 44.78774092501215 35.0 0.0 no 15707 chrXVI_865152r 37987 essential YPR161C 1248 + TCACCTGTCGTGAAAAATCT P|418|A P|418|S S|417|* S|417|L SGV1 Suppressor of Gpa1-Val50 mutation 657.0 0 1 0 0 1.0155577621902154 P23293 0.9562489986419678 0.9498909711837769 0.9298099875450134 0.7978823184967041 0.8271216154098511 0.2063913345336914 42.925589987906726 40.0 0.0 no 15708 chrXVI_865246r 37990 essential YPR161C 1154 + AGCTGATATTAAGAGGTACA A|386|G A|386|V SGV1 Suppressor of Gpa1-Val50 mutation 657.0 0 0 0 0 0.2671361891788657 P23293 0.9484469890594482 0.9504740238189696 0.24816399812698364 0.7517842650413513 40.94180701423551 35.0 0.0 no 15709 chrXVI_865266 37991 essential YPR161C 1137 - GCTTCATGACTTTCTTCCGT A|386|P A|386|T E|385|Q E|385|K SGV1 Suppressor of Gpa1-Val50 mutation 657.0 0 0 0 0 0.03728363257219115 P23293 0.9573720097541808 0.9523990154266356 0.956179976463318 0.9475290179252625 0.23667800426483154 0.8911647200584412 0.0 0.0 53.18627452705322 45.0 0.0 no 15710 chrXVI_865328r 37994 essential YPR161C 1072 + TGTCTGCTAAACACCATCCT S|359|C S|359|F A|360|G A|360|V SGV1 Suppressor of Gpa1-Val50 mutation 657.0 0 0 0 0 0.6100337496588577 P23293 0.945252001285553 0.9294660091400146 0.9484469890594482 0.9504740238189696 0.07999388128519057 0.08345723152160645 0.0 0.0 50.25299895635561 45.0 0.0 no 15711 chrXVI_865361r 37996 essential YPR161C 1039 + TAGCGTTAGATCCTTACAAG A|348|G A|348|V SGV1 Suppressor of Gpa1-Val50 mutation 657.0 0 0 0 0 -0.07224958374715358 P23293 0.9484469890594482 0.9504740238189696 0.14053291082382202 0.10709816217422484 43.77739908505538 40.0 0.0 no 15712 chrXVI_865428 37997 essential YPR161C 975 - CCAAATCTTTCCCTCAACGT G|332|R G|332|S R|330|T R|330|K SGV1 Suppressor of Gpa1-Val50 mutation 657.0 0 0 0 0 0.2447787847952515 P23293 0.941340982913971 0.951104998588562 0.932735025882721 0.955805003643036 0.409954696893692 0.5217083692550659 0.1966902166604996 0.6845644116401672 49.62418820479212 45.0 0.0 no 15713 chrXVI_865560 38004 essential YPR161C 843 - TCCGTTTTTCCCTGTAAAAT silent|ACG>ACC|T|287 silent|ACG>ACA|T|287 D|288|H D|288|N SGV1 Suppressor of Gpa1-Val50 mutation 657.0 0 0 0 0 0.8397695782350372 P23293 0.9486550092697144 0.956179976463318 0.006990307476371528 0.021036718040704727 46.57765167461196 35.0 0.0 no 15714 chrXVI_865561r 38005 essential YPR161C 839 + ACCTATTTTACAGGGAAAAA P|281|R P|281|L P|281|A P|281|S SGV1 Suppressor of Gpa1-Val50 mutation 657.0 0 0 0 0 -1.1855559279513126 P23293 0.9432820081710817 0.9430609941482544 0.9562489986419678 0.9498909711837769 0.0 0.0 0.0 0.0 37.44532871428624 30.0 0.0 no 15715 chrXVI_865691 38009 essential YPR161C 712 - TACGACTACTGATGTATATT V|244|L V|244|I V|243|L V|243|I SGV1 Suppressor of Gpa1-Val50 mutation 657.0 0 1 0 0 -0.07326995706732213 P23293 0.9539830088615416 0.9574310183525084 0.9539830088615416 0.9574310183525084 0.0 0.0 0.0 0.0 38.5003013875612 30.0 0.0 no 15716 chrXVI_865914 38015 essential YPR161C 489 - CACATCTCTAAGTTGATTCT M|169|I M|169|I E|168|D silent|GAG>GAA|E|168 SGV1 Suppressor of Gpa1-Val50 mutation 657.0 0 0 0 0 -0.06651066057368077 P23293 0.9553959965705872 0.9553959965705872 0.94931298494339 0.4380427300930023 0.4380427300930023 0.5641963481903076 42.843629152207825 35.0 0.0 no 15717 chrXVI_865953 38016 essential YPR161C 450 - GACAGATCTGCTACCATATA silent|CTG>CTC|L|156 silent|CTG>CTA|L|156 SGV1 Suppressor of Gpa1-Val50 mutation 657.0 0 0 0 0 -0.9339492651805994 P23293 45.67898728203136 40.0 0.0 no 15718 chrXVI_865966r 38018 essential YPR161C 434 + CTACATGATCCTGCCGTATA Y|146|* silent|TAC>TAT|Y|146 SGV1 Suppressor of Gpa1-Val50 mutation 657.0 0 0 0 0 -0.7389848120474416 P23293 50.02018542172243 45.0 0.0 no 15719 chrXVI_865981 38019 essential YPR161C 422 - TCATGTAGAATGACTTATGT M|147|I M|147|I SGV1 Suppressor of Gpa1-Val50 mutation 657.0 0 0 0 0 0.5085789575499389 P23293 0.9553959965705872 0.9553959965705872 0.147895485162735 0.147895485162735 38.73828041050092 30.0 0.0 no 15720 chrXVI_866193r 38020 essential YPR161C 207 + ACATTTGGTGAGGTTTATAA T|70|R T|70|I SGV1 Suppressor of Gpa1-Val50 mutation 657.0 0 0 0 0 0.7647263228196265 P23293 0.9476869702339172 0.9472420215606691 0.007722657173871994 0.008405511267483234 40.38239780624115 30.0 0.0 no 15721 chrXVI_866236r 38022 essential YPR161C 164 + TTTCCAGAATCATTATCGTG F|56|L silent|TTC>TTT|F|56 Q|57|E Q|57|* SGV1 Suppressor of Gpa1-Val50 mutation 657.0 0 0 0 0 0.4912555257677934 P23293 0.9387490153312684 0.9590039849281312 0.7441843748092651 0.676319420337677 42.391485617629534 35.0 0.0 no 15722 chrXVI_867168r 38028 essential YPR162C 1114 + TATCTAATAATTTAACAGGA S|373|C S|373|F ORC4 Origin Recognition Complex 529.0 0 0 0 0 0.2272904955893939 P54791 0.05365243554115296 0.053690649569034576 31.75980077372526 20.0 0.0 no 15723 chrXVI_867240 38029 essential YPR162C 1045 - GCAGAGTGAACCAAAATTTT C|355|S C|355|Y ORC4 Origin Recognition Complex 529.0 0 0 0 0 -0.103750922897915 P54791 0.7077491879463196 1.0 39.895575997483775 35.0 0.0 no 15724 chrXVI_867338 38030 essential YPR162C 947 - GTCTATTCAAATTCGATCGA R|322|T R|322|K ORC4 Origin Recognition Complex 529.0 0 0 0 0 0.19565205030621896 P54791 0.4497292935848236 1.0 40.772244384560906 35.0 0.0 no 15725 chrXVI_867342 38031 essential YPR162C 943 - ATTCAAATTCGATCGAGGGT L|320|F silent|TTG>TTA|L|320 ORC4 Origin Recognition Complex 529.0 0 0 0 0 0.6896648905327359 P54791 0.15636791288852692 43.284072630533565 40.0 0.0 no 15726 chrXVI_867377r 38032 essential YPR162C 905 + TTCACAATGGAATGAAACGT S|303|* S|303|L Q|304|E Q|304|* ORC4 Origin Recognition Complex 529.0 0 0 0 0 -0.5706397646793167 P54791 0.3504819571971893 1.0 37.33133091123119 35.0 0.0 no 15727 chrXVI_867384 38033 essential YPR162C 901 - TTCATTCCATTGTGAAACCC E|307|Q E|307|K W|305|C W|305|* ORC4 Origin Recognition Complex 529.0 0 0 0 0 0.5168504378648711 P54791 0.5668663382530212 1.0 0.0 47.115967697210074 40.0 0.0 no 15728 chrXVI_867387 38035 essential YPR162C 898 - ATTCCATTGTGAAACCCAGG W|305|C W|305|* W|305|S W|305|* ORC4 Origin Recognition Complex 529.0 0 0 0 0 -0.19536630434671626 P54791 0.0 0.0 48.216648915667236 45.0 0.0 no 15729 chrXVI_867401r 38036 essential YPR162C 881 + TCGCTCTGAAATCTCCCCCT silent|CGC>CGG|R|295 silent|CGC>CGT|R|295 R|295|G R|295|C ORC4 Origin Recognition Complex 529.0 0 0 0 1 -0.6706584443999271 P54791 0.3129319548606873 0.0450553260743618 57.86272706836042 55.00000000000001 0.0 no 15730 chrXVI_867402r 38037 essential YPR162C 880 + TTCGCTCTGAAATCTCCCCC R|295|G R|295|C silent|CGC>CGG|R|295 silent|CGC>CGT|R|295 ORC4 Origin Recognition Complex 529.0 0 1 0 0 0.1625474710781672 P54791 0.3129319548606873 0.0450553260743618 56.44893914524062 55.00000000000001 0.0 no 15731 chrXVI_867533r 38040 essential YPR162C 749 + CACAACGAAATTAAATATCT T|251|R T|251|I T|252|R T|252|M ORC4 Origin Recognition Complex 529.0 0 0 0 0 -0.15545404634544796 P54791 0.008745492435991764 0.009472350589931013 0.008745492435991764 0.004757004790008068 31.59335242000776 25.0 0.0 no 15732 chrXVI_867624r 38041 essential YPR162C 658 + ATACATTTGCTGGGCCTGTG T|221|R T|221|I ORC4 Origin Recognition Complex 529.0 0 0 0 0 0.2377744601117185 P54791 0.4672456979751587 0.1317453533411026 53.14178759547178 50.0 0.0 no 15733 chrXVI_867711 38042 essential YPR162C 574 - ATCTTCATTTCTTGTCTTCG D|198|H D|198|N E|197|Q E|197|K ORC4 Origin Recognition Complex 529.0 0 0 0 0 0.02513375960387146 P54791 0.1167236939072609 0.429402232170105 0.5912037491798401 0.9533121585845948 46.07269323811579 35.0 0.0 no 15734 chrXVI_867871r 38044 essential YPR162C 411 + TCCGAACAAACAGCTATTAA silent|TCC>TCG|S|138 silent|TCC>TCT|S|138 S|138|C S|138|F ORC4 Origin Recognition Complex 529.0 0 0 0 0 0.1910031054219138 P54791 0.007566755171865225 0.00405688164755702 39.29306701028077 35.0 0.0 no 15735 chrXVI_868106r 38046 essential YPR162C 176 + ACTTTATGGCACACTTCCTA L|60|V L|60|F ORC4 Origin Recognition Complex 529.0 0 0 0 0 -0.5079509680444054 P54791 0.044253554195165634 0.028765877708792686 49.26664095855006 40.0 0.0 no 15736 chrXVI_868237 38048 essential YPR162C 48 - TCGTTTGAGTGCCTCTTTAT E|23|Q E|23|K ORC4 Origin Recognition Complex 529.0 0 1 0 0 0.16299591597760196 P54791 0.5976977944374084 0.9217625260353088 50.630892600812274 40.0 0.0 no 15737 chrXVI_868248r 38049 essential YPR162C 34 + TCAATCTTCTCCCAATAAAG silent|GTC>GTG|V|12 silent|GTC>GTT|V|12 L|14|V L|14|F ORC4 Origin Recognition Complex 529.0 0 0 0 1 0.6437398395092185 P54791 41.011490344776526 35.0 0.0 no 15738 chrXVI_875488r 38055 essential YPR165W 123 - ACATAGTTTTCAAAGACAGT V|48|L V|48|I RHO1 Ras HOmolog 209.0 0 0 0 0 -0.9327621482081876 P06780 0.9539830088615416 0.9574310183525084 0.21094052493572235 0.39108359813690186 -0.8280199766159058 -0.3389799892902374 -1.0444200038909912 -0.34002000093460083 38.50127386846305 30.0 1.0 no 15739 chrXVI_875561r 38057 essential YPR165W 196 - ATCATAATCTTCTTGACCAG D|72|H D|72|N RHO1 Ras HOmolog 209.0 0 0 0 0 -0.6299464371839922 P06780 0.9486550092697144 0.956179976463318 0.001196301425807178 0.0051452023908495894 0.03728000074625015 0.04326000064611435 0.33086666464805603 -0.05193332955241203 42.40616289350101 35.0 1.0 no 15740 chrXVI_875713r 38058 essential YPR165W 348 - TTACAACCAACAAGAATAAT C|122|S C|122|Y G|121|A G|121|D RHO1 Ras HOmolog 209.0 0 0 0 0 -6.319193156243749 P06780 0.9421560168266296 0.9290120005607604 0.9499930143356324 0.9446240067481996 0.3347882926464081 0.03747297078371048 0.08266634494066237 0.0007776772254146637 0.9580000042915344 2.920799970626831 1.1512000560760498 7.695000171661378 32.87908143934811 25.0 1.0 yes 15741 chrXVI_875762r 38059 essential YPR165W 397 - TTCTTGTCTTAATTGTTCAA E|139|Q E|139|K RHO1 Ras HOmolog 209.0 0 0 0 0 0.2913363358841053 P06780 0.956179976463318 0.9475290179252625 0.6766124963760376 1.0 -0.6726999878883362 -0.7702999711036682 39.61866172227707 25.0 1.0 no 15742 chrXVI_875787 38060 essential YPR165W 419 + TCAACAACCCGTTACATCAC Q|141|E Q|141|* Q|142|E Q|142|* RHO1 Ras HOmolog 209.0 0 0 0 0 0.2780570746626212 P06780 0.9590039849281312 0.9590039849281312 0.5015180110931396 1.0 1.6043599843978882 0.3704800009727478 0.735040009021759 0.5024799704551697 46.19631063961418 45.0 1.0 no 15743 chrXVI_875791 38062 essential YPR165W 423 + CAACCCGTTACATCACAGGA P|143|A P|143|S P|143|R P|143|L RHO1 Ras HOmolog 209.0 0 0 0 0 0.35939964530872903 P06780 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.02085965871810913 0.008666456677019596 0.0074085830710828296 0.041640404611825936 2.857719898223877 3.595400094985962 3.7534999847412114 1.9529999494552608 49.704912134046204 50.0 1.0 no 15744 chrXVI_878135r 38065 essential YPR168W 62 - ACTCAATAATCGAAGCCACT E|27|Q E|27|K E|27|D silent|GAG>GAA|E|27 NUT2 Negative regulation of URS Two 157.0 0 0 0 0 -0.2683915224696046 Q06213 0.16134218871593475 0.03192178905010224 0.30997562408447266 43.33045343403183 40.0 1.0 no 15745 chrXVI_878202r 38066 essential YPR168W 129 - ATCATTCCCTTGGTGGCTTC M|49|I M|49|I G|48|A G|48|E NUT2 Negative regulation of URS Two 157.0 0 0 0 0 1.1581458313195725 Q06213 0.20840252935886386 0.20840252935886386 1.0 0.5780071616172789 57.207649107741595 50.0 1.0 no 15746 chrXVI_878282 38067 essential YPR168W 206 + TCCTCAATCCAGCTTGTCTA P|70|R P|70|L P|70|A P|70|S NUT2 Negative regulation of URS Two 157.0 0 0 0 0 0.175621611108586 Q06213 0.6857239603996277 1.0 0.9997328519821168 0.9394060969352722 53.74228389302624 45.0 1.0 no 15747 chrXVI_878283r 38068 essential YPR168W 210 - ACCTTAGACAAGCTGGATTG K|76|N silent|AAG>AAA|K|76 V|77|L V|77|M NUT2 Negative regulation of URS Two 157.0 0 0 0 0 0.34915116682295705 Q06213 0.8065171241760254 1.0 0.2480184435844421 45.917785253501854 45.0 1.0 no 15748 chrXVI_878297 38070 essential YPR168W 221 + GTCTAAGGTGGACATTCCCT S|75|C S|75|F NUT2 Negative regulation of URS Two 157.0 0 0 0 0 0.13906882732714404 Q06213 0.05416489765048027 0.05467591434717178 53.836179656965335 50.0 1.0 no 15749 chrXVI_878399r 38071 essential YPR168W 326 - GCATCTTGCCTCTTTGATAT M|115|I M|115|I K|114|N silent|AAG>AAA|K|114 NUT2 Negative regulation of URS Two 157.0 0 0 0 0 0.040161975183205516 Q06213 0.26981413364410395 0.26981413364410395 0.0 50.767512691594284 40.0 1.0 no 15750 chrXVI_878896 38074 essential YPR169W 206 + TGACACTGCAACTACAGGCA D|70|E silent|GAC>GAT|D|70 T|71|S T|71|I JIP5 Jumonji domain Interacting Protein 492.0 0 0 0 0 0.6075799402022375 Q06214 0.9532920122146606 0.9491789937019348 0.9472420215606691 0.32204294204711914 0.756717324256897 0.1753596067428589 48.70167005107919 50.0 1.0 no 15751 chrXVI_879036 38077 essential YPR169W 346 + ACTTGGGCGTAAAAACACTT D|116|E silent|GAC>GAT|D|116 JIP5 Jumonji domain Interacting Protein 492.0 0 1 0 0 0.5308375254967497 Q06214 0.9532920122146606 0.9501758217811584 41.87937087513637 40.0 1.0 no 15752 chrXVI_879090r 38079 essential YPR169W 403 - ACCTTTAGAATCAAAGCACA G|141|R G|141|S G|141|A G|141|D JIP5 Jumonji domain Interacting Protein 492.0 0 0 0 0 -0.09331549230723074 Q06214 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.0 0.0 0.0 0.0 41.27642756068542 35.0 1.0 no 15753 chrXVI_879133 38080 essential YPR169W 443 + ATCGGATAATGTTTTAAAAA S|149|W S|149|L JIP5 Jumonji domain Interacting Protein 492.0 0 0 0 0 0.4504187932585482 Q06214 0.9288619756698608 0.9298099875450134 0.034131992608308785 0.43939948081970215 31.27136637583334 20.0 1.0 no 15754 chrXVI_879260 38082 essential YPR169W 570 + ACTCACCCATTCATTTTAAT H|192|D H|192|Y T|191|S T|191|I JIP5 Jumonji domain Interacting Protein 492.0 0 0 0 0 0.05582882460843466 Q06214 0.9473130106925964 0.9489949941635132 0.9491789937019348 0.9472420215606691 0.2281569540500641 0.017783241346478462 0.05858062207698823 0.005697887390851975 44.48972014435577 30.0 1.0 no 15755 chrXVI_879401 38085 essential YPR169W 711 + GCATATAAATTCATTTCTTT A|238|G A|238|V JIP5 Jumonji domain Interacting Protein 492.0 0 0 0 0 0.2899645176198208 Q06214 0.9484469890594482 0.9504740238189696 0.1526632010936737 1.0 36.441044352072886 20.0 1.0 no 15756 chrXVI_879470r 38088 essential YPR169W 783 - TCCTCGTTTCCAGCTACGTT E|267|D silent|GAG>GAA|E|267 D|268|H D|268|N JIP5 Jumonji domain Interacting Protein 492.0 0 0 0 0 -0.29743742610925905 Q06214 0.94931298494339 0.9486550092697144 0.956179976463318 0.024977685883641243 0.060731776058673866 56.76014303082393 50.0 1.0 no 15757 chrXVI_879571r 38090 essential YPR169W 884 - CCTCGCCCATCCCACACAAA E|301|Q E|301|K E|301|D silent|GAG>GAA|E|301 JIP5 Jumonji domain Interacting Protein 492.0 0 0 0 0 0.3845932926705591 Q06214 0.956179976463318 0.9475290179252625 0.94931298494339 0.054187748581171036 0.04626457393169403 0.21787315607070926 58.08569611412128 60.0 1.0 no 15758 chrXVI_879561 38091 essential YPR169W 871 + TAGCAGATACCCTTTTGTGT A|292|G A|292|V JIP5 Jumonji domain Interacting Protein 492.0 0 0 0 0 0.6861080828730659 Q06214 0.9484469890594482 0.9504740238189696 1.0 0.12439889460802077 50.39432251551182 40.0 1.0 no 15759 chrXVI_879603r 38093 essential YPR169W 916 - ATTCTTATTCGGTTTCCAGA K|311|N silent|AAG>AAA|K|311 JIP5 Jumonji domain Interacting Protein 492.0 0 0 0 0 0.4623119536601669 Q06214 0.9355990290641784 0.12475058436393738 47.41721809855938 35.0 1.0 no 15760 chrXVI_879614r 38094 essential YPR169W 927 - TCTTCCAAATCATTCTTATT D|316|H D|316|N E|315|Q E|315|K JIP5 Jumonji domain Interacting Protein 492.0 0 0 0 0 0.10943204523861697 Q06214 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.0 0.0 0.4702149629592896 0.6959779858589172 40.68109786604333 25.0 1.0 no 15761 chrXVI_879787r 38095 essential YPR169W 1100 - TGACTTCATCCAATTCACTG V|373|L V|373|I E|372|Q E|372|K JIP5 Jumonji domain Interacting Protein 492.0 0 0 0 0 -0.20466455159208188 Q06214 0.9539830088615416 0.9574310183525084 0.956179976463318 0.9475290179252625 0.035799764096736915 0.05606352537870407 0.02202674001455307 0.017246074974536896 44.68261740045557 40.0 1.0 no 15762 chrXVI_889088 38098 essential YPR175W 114 + TCTGCTCTTGCAGAATTCGT S|39|C S|39|F A|40|G A|40|V DPB2 DNA Polymerase B subunit 2 689.0 0 0 0 0 -0.03498296793321967 P24482 0.045350536704063416 0.04329092428088188 0.3854912519454956 0.29192277789115906 50.441986146151756 45.0 1.0 no 15763 chrXVI_889200 38100 essential YPR175W 226 + GCCTTTTCATCGACCAGAGC L|77|V L|77|F silent|GGC>GGG|G|76 silent|GGC>GGT|G|76 DPB2 DNA Polymerase B subunit 2 689.0 0 0 0 0 -1.0286118962066724 P24482 0.2950967252254486 0.030532417818903927 55.603365802421315 55.00000000000001 1.0 no 15764 chrXVI_889201 38101 essential YPR175W 227 + CCTTTTCATCGACCAGAGCG L|77|V L|77|F F|78|L silent|TTC>TTT|F|78 DPB2 DNA Polymerase B subunit 2 689.0 0 0 0 0 -0.9364510691708974 P24482 0.2950967252254486 0.030532417818903927 0.0 52.7086131795429 55.00000000000001 1.0 no 15765 chrXVI_889213r 38102 essential YPR175W 242 - TAACTTCTTTAACCCCGCTC V|87|L V|87|I E|86|Q E|86|K DPB2 DNA Polymerase B subunit 2 689.0 0 0 0 0 0.2529367772362293 P24482 0.039895977824926376 0.19856514036655426 0.5924966335296631 0.9032631516456604 50.177522791482936 45.0 1.0 no 15766 chrXVI_889289 38103 essential YPR175W 315 + CAACATGAGGAGAATATCTT H|107|D H|107|Y DPB2 DNA Polymerase B subunit 2 689.0 0 0 0 0 0.9320185140658994 P24482 0.6047629714012146 0.10140559077262877 38.08146284162547 35.0 1.0 no 15767 chrXVI_889554r 38110 essential YPR175W 583 - TAGCCCATTCTGCTTTTTAT silent|GGG>GGC|G|200 silent|GGG>GGA|G|200 G|200|A G|200|E DPB2 DNA Polymerase B subunit 2 689.0 0 0 0 0 0.4510518997945864 P24482 0.8401951789855957 1.0 50.53011572212552 35.0 1.0 no 15768 chrXVI_889737r 38112 essential YPR175W 766 - TTGCTGCTGTCGGTTAGTAT Q|261|H silent|CAG>CAA|Q|261 Q|260|H silent|CAG>CAA|Q|260 DPB2 DNA Polymerase B subunit 2 689.0 0 0 0 0 1.1712395140006069 P24482 0.12303576618433 0.12897136807441711 52.32048674840678 45.0 1.0 no 15769 chrXVI_889747r 38113 essential YPR175W 776 - TACTGCTGGATTGCTGCTGT S|265|T S|265|N S|264|T S|264|N DPB2 DNA Polymerase B subunit 2 689.0 0 0 0 0 -0.9756955069016742 P24482 0.9114260673522948 0.6369295120239258 0.6093313097953796 0.5057529807090759 54.14203932748802 50.0 1.0 no 15770 chrXVI_889807 38114 essential YPR175W 833 + TGCTCAAAACTTTCTACTAT A|279|G A|279|V Q|280|E Q|280|* DPB2 DNA Polymerase B subunit 2 689.0 0 0 0 0 -0.03208171081930042 P24482 1.0 0.016984637826681137 0.30390021204948425 39.28711214226951 30.0 1.0 no 15771 chrXVI_889809 38115 essential YPR175W 835 + CTCAAAACTTTCTACTATTG Q|280|E Q|280|* DPB2 DNA Polymerase B subunit 2 689.0 0 0 0 0 0.6530031676444422 P24482 0.30390021204948425 36.049003878247454 30.0 1.0 no 15772 chrXVI_889874r 38116 essential YPR175W 903 - TCAATTTCGACAGATCCAGA D|308|H D|308|N DPB2 DNA Polymerase B subunit 2 689.0 0 0 0 0 1.2411762845538543 P24482 0.02010298706591129 0.3908977806568146 44.38633593786466 40.0 1.0 no 15773 chrXVI_889913r 38118 essential YPR175W 942 - ACGTAGTAATGGCCTTGTGT V|321|L V|321|M DPB2 DNA Polymerase B subunit 2 689.0 0 0 0 0 0.3828439314892563 P24482 0.18124175071716309 0.1450415402650833 50.470290980356815 45.0 1.0 no 15774 chrXVI_889997 38122 essential YPR175W 1023 + ACCTCCATGACTTTACCCCC silent|ACC>ACG|T|342 silent|ACC>ACT|T|342 T|342|S T|342|I DPB2 DNA Polymerase B subunit 2 689.0 0 0 0 0 -1.6790657570197856 P24482 0.8168681859970093 0.047087796032428735 59.63103862840029 55.00000000000001 1.0 no 15775 chrXVI_890089 38125 essential YPR175W 1115 + TAACAATTTCATTGCTCGTT N|373|K silent|AAC>AAT|N|373 DPB2 DNA Polymerase B subunit 2 689.0 0 0 0 0 0.1339395196467185 P24482 0.9194576740264891 41.02929737613926 30.0 1.0 no 15776 chrXVI_890194r 38126 essential YPR175W 1223 - TCATAATTTTCAAATCATCT M|414|I M|414|I DPB2 DNA Polymerase B subunit 2 689.0 0 0 0 0 -0.33403279079043513 P24482 0.20319350063800806 0.20319350063800806 34.73280494333159 20.0 1.0 no 15777 chrXVI_890159 38127 essential YPR175W 1185 + GATCATAAATTTGTAATTCT H|397|D H|397|Y DPB2 DNA Polymerase B subunit 2 689.0 0 0 0 0 0.636164233758088 P24482 0.0972968116402626 0.022718019783496857 33.35177518277891 20.0 1.0 no 15778 chrXVI_890258 38129 essential YPR175W 1284 + CCGACCCTATTAATTTGGCA P|429|R P|429|L T|430|S T|430|I DPB2 DNA Polymerase B subunit 2 689.0 0 0 0 0 -0.5162992856316363 P24482 0.0 0.0 0.07679332792758943 1.0 50.35060472173718 45.0 1.0 no 15779 chrXVI_890425 38133 essential YPR175W 1451 + TCCAGGTCCTAACGATTTAT P|485|R P|485|L P|485|A P|485|S DPB2 DNA Polymerase B subunit 2 689.0 0 0 0 0 0.20594808422119454 P24482 0.0 0.0 0.0 0.0 47.670161756604394 40.0 1.0 no 15780 chrXVI_891396 38139 essential YPR176C 663 - CTACCGTTTAGTCCACCTTC G|227|A G|227|D G|227|R G|227|S BET2 Blocked Early in Transport 325.0 0 0 0 0 -3.928933176345683 P20133 0.0 0.0 0.0 0.0 54.644524239756386 50.0 0.0 yes 15781 chrXVI_891709 38150 essential YPR176C 350 - CATCTTCCAATTGATTCCCA D|123|H D|123|N E|122|Q E|122|K BET2 Blocked Early in Transport 325.0 0 0 0 0 -0.8059875946709816 P20133 0.019558092579245567 0.260722815990448 0.4248531758785248 0.6102350354194641 49.71456093424962 40.0 0.0 no 15782 chrXVI_891725r 38152 essential YPR176C 331 + GCTTGATTTCCTTCATCCGT silent|CGC>CGG|R|111 silent|CGC>CGT|R|111 BET2 Blocked Early in Transport 325.0 0 0 0 0 0.2557474473722522 P20133 54.59814708310569 45.0 0.0 no 15783 chrXVI_891726r 38153 essential YPR176C 330 + CGCTTGATTTCCTTCATCCG silent|CGC>CGG|R|111 silent|CGC>CGT|R|111 BET2 Blocked Early in Transport 325.0 0 0 0 0 0.8921742197451645 P20133 52.72337681846267 50.0 0.0 no 15784 chrXVI_891874r 38155 essential YPR176C 182 + ATCATTTGTTCTGAGCTGTT S|62|* S|62|L BET2 Blocked Early in Transport 325.0 0 0 0 0 -0.5874622124170821 P20133 0.03500794246792793 47.39292197609336 35.0 0.0 no 15785 chrXVI_891875r 38156 essential YPR176C 181 + TATCATTTGTTCTGAGCTGT S|62|* S|62|L BET2 Blocked Early in Transport 325.0 0 0 0 0 -0.2252810890341445 P20133 0.03500794246792793 46.49233499529112 35.0 0.0 no 15786 chrXVI_891903 38157 essential YPR176C 156 - TCTTCTTTCACAAATGTCTC E|59|Q E|59|K E|58|Q E|58|K BET2 Blocked Early in Transport 325.0 0 0 0 0 0.2787341261391661 P20133 0.18941710889339447 0.16304956376552582 0.2873205244541168 0.14255976676940918 42.82349544711121 35.0 0.0 no 15787 chrXVI_891956r 38158 essential YPR176C 100 + TTCGTTTGAATGGGATATAT R|35|G R|35|C BET2 Blocked Early in Transport 325.0 0 0 0 0 -0.4842526135911626 P20133 0.005791621282696724 0.00113686581607908 39.44291978967175 30.0 0.0 no 15788 chrXVI_891965r 38159 essential YPR176C 91 + CCGAGCATCTTCGTTTGAAT silent|ACC>ACG|T|31 silent|ACC>ACT|T|31 H|33|D H|33|Y BET2 Blocked Early in Transport 325.0 0 0 0 0 -0.02576573923931413 P20133 0.013048635795712471 0.2920498847961426 -0.3352000117301941 -0.7937999963760376 0.4499000012874603 -0.6392999887466431 48.3223409623289 45.0 0.0 no 15789 chrXVI_891966r 38160 essential YPR176C 90 + ACCGAGCATCTTCGTTTGAA silent|ACC>ACG|T|31 silent|ACC>ACT|T|31 T|31|S T|31|I BET2 Blocked Early in Transport 325.0 0 0 0 0 -0.2670891984130745 P20133 0.26189443469047546 0.0027456004172563553 48.77012303239429 45.0 0.0 no 15790 chrXVI_892362 38162 essential YPR178W 30 + CCGGTAGATTTGCAACATAA P|11|R P|11|L PRP4 Pre-mRNA Processing 465.0 0 0 0 0 -0.4781606891147368 P20053 0.9432820081710817 0.9430609941482544 0.6528831124305725 0.29779377579689026 43.65022100804384 40.0 1.0 no 15791 chrXVI_892451r 38163 essential YPR178W 122 - CTTCTTCTGGTATCTTCTCC E|47|Q E|47|K E|46|Q E|46|K PRP4 Pre-mRNA Processing 465.0 0 0 0 0 0.006816884363698318 P20053 0.956179976463318 0.9475290179252625 0.956179976463318 0.9475290179252625 0.12589582800865173 0.14413845539093018 0.024806629866361615 0.031011251732707024 53.17871368696178 45.0 1.0 no 15792 chrXVI_892464r 38164 essential YPR178W 135 - CTCACCTCAAGATCTTCTTC silent|GTG>GTC|V|51 silent|GTG>GTA|V|51 V|51|L V|51|M PRP4 Pre-mRNA Processing 465.0 0 0 0 0 0.2002235336834311 P20053 0.9539830088615416 0.9587630033493042 0.030162284150719643 0.0060841976664960384 48.84895183580113 45.0 1.0 no 15793 chrXVI_892493 38165 essential YPR178W 161 + GCTTTCAATTTTAAAGAAGC L|55|V L|55|F S|56|* S|56|L PRP4 Pre-mRNA Processing 465.0 0 0 0 0 -0.04170704128635172 P20053 0.9512209892272948 0.9587849974632264 0.9298099875450134 0.0 0.0 0.2999703884124756 36.883428379136895 30.0 1.0 no 15794 chrXVI_892512r 38166 essential YPR178W 183 - TCTTCATTCTCCACTACTTC D|68|H D|68|N E|67|Q E|67|K PRP4 Pre-mRNA Processing 465.0 0 0 0 0 0.3068054372967439 P20053 0.9486550092697144 0.956179976463318 0.956179976463318 0.9475290179252625 0.16303512454032898 0.8336620330810547 0.0 0.0 49.40670976565156 40.0 1.0 no 15795 chrXVI_892874 38171 essential YPR178W 542 + TTCTTTATCTACCGATGACA S|182|C S|182|F PRP4 Pre-mRNA Processing 465.0 0 0 0 0 -0.27676776460995844 P20053 0.945252001285553 0.9294660091400146 0.08532421290874481 0.14279530942440033 44.20314859821116 35.0 1.0 no 15796 chrXVI_893176 38174 essential YPR178W 844 + GTGCCTCTCATGATATGACT A|283|G A|283|V silent|GCC>GCG|A|283 silent|GCC>GCT|A|283 PRP4 Pre-mRNA Processing 465.0 0 0 0 0 0.0021949025736860968 P20053 0.9484469890594482 0.9504740238189696 0.03400997817516327 0.011197753250598907 50.496664722346345 45.0 1.0 no 15797 chrXVI_893235 38175 essential YPR178W 903 + CTACAAGAAGGCCATGATAA Q|303|E Q|303|* PRP4 Pre-mRNA Processing 465.0 0 0 0 0 -1.5077551168891172 P20053 0.9590039849281312 0.0 41.14344009224658 40.0 1.0 no 15798 chrXVI_893246r 38176 essential YPR178W 917 - GACTAAACACTCCCTTATCA S|312|T S|312|N PRP4 Pre-mRNA Processing 465.0 0 0 0 0 0.5931908996270059 P20053 0.9512869715690612 0.9536849856376648 0.8039162158966064 0.06982630491256714 45.57604866140167 40.0 1.0 no 15799 chrXVI_896046r 38179 essential YPR180W 88 - TACTTTTGCTGATCTCATAT V|36|L V|36|I AOS1 Activation Of Smt3p 347.0 0 1 0 0 0.09153603312527453 Q06624 0.9539830088615416 0.9574310183525084 0.08347395062446594 1.0 42.842828550240476 30.0 1.0 no 15800 chrXVI_896199 38184 essential YPR180W 238 + GCTCTGAAGATGTTGGCCAA S|81|C S|81|F silent|GGC>GGG|G|80 silent|GGC>GGT|G|80 AOS1 Activation Of Smt3p 347.0 0 0 0 0 -0.23434095985964465 Q06624 0.945252001285553 0.9294660091400146 0.046340558677911765 0.045333150774240494 0.04720000177621842 -0.3578000068664551 50.84005276099805 50.0 1.0 no 15801 chrXVI_896261r 38185 essential YPR180W 303 - TCAAAGTTCAACTCTATACG D|108|H D|108|N AOS1 Activation Of Smt3p 347.0 0 0 0 0 -0.11593858729844267 Q06624 0.9486550092697144 0.956179976463318 0.11210644245147704 0.7228293418884277 38.00037434726437 35.0 1.0 no 15802 chrXVI_896263r 38187 essential YPR180W 305 - TATCAAAGTTCAACTCTATA D|108|H D|108|N AOS1 Activation Of Smt3p 347.0 0 0 0 0 0.6139446310156187 Q06624 0.9486550092697144 0.956179976463318 0.11210644245147704 0.7228293418884277 35.479404402255454 25.0 1.0 no 15803 chrXVI_896399 38189 essential YPR180W 438 + AACATTCCATTATATGTTGC N|147|K silent|AAC>AAT|N|147 P|149|A P|149|S AOS1 Activation Of Smt3p 347.0 0 0 0 0 0.06459812988878189 Q06624 0.9439849853515624 0.9562489986419678 0.9498909711837769 0.3012191653251648 0.07739304006099701 0.05414600670337677 41.44066008962256 30.0 1.0 no 15804 chrXVI_896595 38191 essential YPR180W 634 + TCAAGACCAAGAACTGCTAT I|212|M silent|ATC>ATT|I|212 T|214|S T|214|I AOS1 Activation Of Smt3p 347.0 0 0 0 0 0.8257272478700413 Q06624 0.9598389863967896 0.9491789937019348 0.9472420215606691 0.04613083600997925 0.2882890701293945 0.5877185463905334 -0.1997999995946884 42.40199310487219 40.0 1.0 no 15805 chrXVI_896618r 38192 essential YPR180W 660 - GTGCTTAAAACTTCGTTCAG S|226|T S|226|N AOS1 Activation Of Smt3p 347.0 0 0 0 0 0.6194408090832466 Q06624 0.9512869715690612 0.9536849856376648 0.5932166576385498 0.5038780570030212 42.28080559252117 40.0 1.0 no 15806 chrXVI_896706r 38194 essential YPR180W 748 - ACCATATTGCAATAAGGACA G|256|R G|256|S G|256|A G|256|D AOS1 Activation Of Smt3p 347.0 0 0 0 0 0.902116642088354 Q06624 0.941340982913971 0.951104998588562 0.9499930143356324 0.9446240067481996 0.553057849407196 0.7299898266792297 0.7520402669906616 0.618084728717804 41.52231006211781 35.0 1.0 no 15807 chrXVI_896734r 38195 essential YPR180W 776 - AGCTTATGGCCTTGCCCTTT S|265|T S|265|N AOS1 Activation Of Smt3p 347.0 0 0 0 0 0.31626412295089 Q06624 0.9512869715690612 0.9536849856376648 0.21819378435611725 0.3138779401779175 60.114695719340496 50.0 1.0 no 15808 chrXVI_898034r 38196 essential YPR181C 1611 + CACAAGGCTGAAACCGATGA H|538|Q silent|CAC>CAT|H|538 SEC23 SECretory 768.0 0 1 0 0 -1.2457400649804835 P15303 0.9588389992713928 0.032022319734096534 -0.946399986743927 44.769508990159686 50.0 0.0 no 15809 chrXVI_898108 38199 essential YPR181C 1540 - TGCAATGGCAGGAGTACCGA A|520|P A|520|T SEC23 SECretory 768.0 0 0 0 0 -1.0716626362643706 P15303 0.9573720097541808 0.9523990154266356 0.13422979414463046 0.15931770205497742 0.3009999990463257 1.982200026512146 52.10081215820282 55.00000000000001 0.0 no 15810 chrXVI_898175r 38203 essential YPR181C 1470 + ACTACTTATCAACACTCCTC T|491|S T|491|I T|492|S T|492|I SEC23 SECretory 768.0 0 0 0 0 0.11292348972142688 P15303 0.9491789937019348 0.9472420215606691 0.9491789937019348 0.9472420215606691 0.0 0.0 0.4319518804550171 0.3942650556564331 2.208199977874756 -1.65339994430542 0.4930000007152557 -2.0773999691009517 45.35663802484766 40.0 0.0 no 15811 chrXVI_898300 38205 essential YPR181C 1348 - ATACGAGTGATAAGGCGATA silent|TCG>TCC|S|455 silent|TCG>TCA|S|455 SEC23 SECretory 768.0 0 0 0 0 -2.7230503625739213 P15303 41.46025657547784 40.0 0.0 yes 15812 chrXVI_898355r 38207 essential YPR181C 1290 + AACATCAGTGAATCTGAAAT N|431|K silent|AAC>AAT|N|431 I|432|M silent|ATC>ATT|I|432 SEC23 SECretory 768.0 0 0 0 0 -0.305139608518989 P15303 0.9439849853515624 0.9598389863967896 0.2917948663234711 0.0060273357667028895 4.5218000411987305 0.4004000127315521 35.48469800633279 30.0 0.0 no 15813 chrXVI_898497r 38208 essential YPR181C 1148 + ATACTTGAGATTGTTTGCCA Y|384|* silent|TAC>TAT|Y|384 SEC23 SECretory 768.0 0 0 0 0 -0.7966507675495001 P15303 45.79522612475074 35.0 0.0 no 15814 chrXVI_898561 38210 essential YPR181C 1087 - CAACACACCTCCAGTAGAGT silent|GTG>GTC|V|368 silent|GTG>GTA|V|368 V|368|L V|368|M SEC23 SECretory 768.0 0 0 0 0 -5.307972912054415 P15303 0.9539830088615416 0.9587630033493042 0.656875729560852 0.21909937262535092 0.19900000095367432 -0.11919999867677687 50.701676065572656 50.0 0.0 yes 15815 chrXVI_898625r 38213 essential YPR181C 1020 + CACACTGTTGATATTTTTGC H|341|Q silent|CAC>CAT|H|341 T|342|S T|342|I SEC23 SECretory 768.0 0 0 0 0 0.9068148178577328 P15303 0.9588389992713928 0.9491789937019348 0.9472420215606691 0.008490758948028088 0.0359777994453907 0.4663227498531342 0.7861999869346619 0.4101999998092651 2.966599941253662 42.625880639567974 35.0 0.0 no 15816 chrXVI_898649r 38214 essential YPR181C 996 + GCACAAAGAGTTGCCGCCAA Q|334|E Q|334|* A|333|G A|333|V SEC23 SECretory 768.0 0 0 0 0 0.7063938584757423 P15303 0.9590039849281312 0.9484469890594482 0.9504740238189696 0.7177832722663879 0.17861656844615936 0.00697007542476058 0.17419999837875366 1.5462000370025637 5.682000160217285 52.229995777439505 55.00000000000001 0.0 no 15817 chrXVI_898672 38216 essential YPR181C 976 - AATCTGGTTGTAAAACTTAC Q|331|H silent|CAG>CAA|Q|331 SEC23 SECretory 768.0 0 0 0 0 0.674982940992026 P15303 0.9570760130882264 0.10547816753387453 0.6344000101089478 35.771736135679824 30.0 0.0 no 15818 chrXVI_898695r 38217 essential YPR181C 950 + TCACGCGCAACATTACAAGA H|318|Q silent|CAC>CAT|H|318 H|318|D H|318|Y SEC23 SECretory 768.0 0 0 0 0 -0.2737149265187591 P15303 0.9588389992713928 0.9473130106925964 0.9489949941635132 0.22953622043132785 0.25364652276039124 0.03539613634347916 -0.765999972820282 0.3664000034332275 -0.4763999879360199 -0.5189399719238281 0.5023800134658813 0.07317999750375748 44.50691650555808 45.0 0.0 no 15819 chrXVI_898760 38218 essential YPR181C 888 - TCTGAGTTAACAATCAAACC E|303|Q E|303|K SEC23 SECretory 768.0 0 0 0 0 -0.7895551314474505 P15303 0.956179976463318 0.9475290179252625 0.11310458183288576 0.2174189239740372 -0.3982000052928925 -0.8356000185012817 38.164558930505216 35.0 0.0 no 15820 chrXVI_898941r 38228 essential YPR181C 704 + GTTCAAACTGAATCAATTAC F|236|L silent|TTC>TTT|F|236 SEC23 SECretory 768.0 0 0 0 0 0.10120201333077622 P15303 0.9387490153312684 0.12158173322677612 0.3515999913215637 0.3783000111579895 34.611747641764175 30.0 0.0 no 15821 chrXVI_898990r 38231 essential YPR181C 655 + TTACGCCCTTCTCTTTGAAT T|220|R T|220|M P|221|A P|221|S SEC23 SECretory 768.0 0 0 0 0 -0.6179770430615592 P15303 0.9476869702339172 0.9502379894256592 0.9562489986419678 0.9498909711837769 0.5231000781059265 0.11758119612932205 0.8955679535865784 0.6965965032577515 -0.3075999915599823 -0.8116000294685364 1.1585999727249146 0.8733999729156494 -2.9100000858306885 -1.7699999809265137 1.7916001081466677 1.885266661643982 49.64154431402255 40.0 0.0 no 15822 chrXVI_899188 38239 essential YPR181C 460 - GATCAACCCAATCAGCGCGT L|159|F silent|TTG>TTA|L|159 silent|GGG>GGC|G|158 silent|GGG>GGA|G|158 SEC23 SECretory 768.0 0 0 0 0 1.0564462244289023 P15303 0.9587849974632264 0.1341720074415207 0.8248000144958496 52.891739626249496 55.00000000000001 0.0 no 15823 chrXVI_899195r 38241 essential YPR181C 450 + TTACCTCCCAACGCGCTGAT P|152|A P|152|S P|152|R P|152|L SEC23 SECretory 768.0 0 0 0 0 -0.4100983949862265 P15303 0.9562489986419678 0.9498909711837769 0.9432820081710817 0.9430609941482544 0.0 0.0 0.0 0.0 2.446000099182129 2.983999967575073 1.863800048828125 1.3228000402450562 3.5962200164794917 4.244959831237793 8.479900360107424 3.5062201023101807 55.39875234586179 55.00000000000001 0.0 no 15824 chrXVI_899373r 38242 essential YPR181C 272 + ACAGTACACCAACTTGTCAC Q|92|E Q|92|* Y|93|* silent|TAC>TAT|Y|93 SEC23 SECretory 768.0 0 0 0 0 -0.11385317009378187 P15303 0.9590039849281312 0.11671480536460875 0.022600000724196437 46.67222400253604 45.0 0.0 no 15825 chrXVI_899429 38244 essential YPR181C 219 - CAACTCCAGGACGAATTGCG S|79|T S|79|N W|78|C W|78|* SEC23 SECretory 768.0 0 1 0 0 -7.0066768813938305 P15303 0.9512869715690612 0.9536849856376648 0.8858469724655151 0.7048094868659973 0.553191602230072 0.0008077999227680267 -0.6970000267028809 -0.03720000013709068 3.2932000160217285 47.244195777574255 55.00000000000001 0.0 yes 15826 chrXVI_899447 38245 essential YPR181C 201 - CGCGGATCAATCACACAGTA silent|CCG>CCC|P|73 silent|CCG>CCA|P|73 SEC23 SECretory 768.0 0 0 0 0 -2.567171460580016 P15303 47.37899605752267 50.0 0.0 yes 15827 chrXVI_899498 38247 essential YPR181C 150 - GAACACACAACTGGATTGTA C|56|S C|56|Y silent|GTG>GTC|V|55 silent|GTG>GTA|V|55 SEC23 SECretory 768.0 1 Series([], Name: modification, dtype: object) 0 0 0 -2.3445858545160823 P15303 0.9421560168266296 0.9290120005607604 0.009529368951916695 0.006055450998246671 7.685800075531006 28.14800071716309 40.92326757648294 40.0 0.0 yes 15828 chrXVI_899499 38249 essential YPR181C 149 - AACACACAACTGGATTGTAT C|56|S C|56|Y silent|GTG>GTC|V|55 silent|GTG>GTA|V|55 SEC23 SECretory 768.0 1 Series([], Name: modification, dtype: object) 0 0 0 -5.069980443089482 P15303 0.9421560168266296 0.9290120005607604 0.009529368951916695 0.006055450998246671 7.685800075531006 28.14800071716309 39.769871849016226 35.0 0.0 yes 15829 chrXVI_899568r 38251 essential YPR181C 77 + TAACAGCAACGTCGTCCCTG N|27|K silent|AAC>AAT|N|27 S|28|R silent|AGC>AGT|S|28 SEC23 SECretory 768.0 0 0 0 0 -0.20691809056016608 P15303 0.9439849853515624 0.9417110085487366 0.10778167098760603 1.0 -0.12319999933242798 0.008200000040233135 51.25955905292614 55.00000000000001 0.0 no 15830 chrXVI_899500 38252 essential YPR181C 148 - ACACACAACTGGATTGTATG silent|GTG>GTC|V|55 silent|GTG>GTA|V|55 C|56|S C|56|Y SEC23 SECretory 768.0 0 0 1 Series([], Name: modification, dtype: object) 0 -1.0498276071993924 P15303 0.9421560168266296 0.9290120005607604 0.009529368951916695 0.006055450998246671 7.685800075531006 28.14800071716309 41.15479469398838 40.0 0.0 no 15831 chrXVI_900812r 38256 essential YPR183W 60 - GCAAACAATCTGGTTGTTAA A|27|P A|27|T L|25|F silent|TTG>TTA|L|25 DPM1 Dolichol Phosphate Mannose synthase 267.0 0 1 0 0 -0.5724351717469672 P14020 0.27872079610824585 0.565118134021759 0.046622492372989655 40.243467098874866 35.0 1.0 no 15832 chrXVI_900813r 38257 essential YPR183W 61 - GGCAAACAATCTGGTTGTTA A|27|P A|27|T L|25|F silent|TTG>TTA|L|25 DPM1 Dolichol Phosphate Mannose synthase 267.0 0 1 0 0 -0.5335899095181698 P14020 0.27872079610824585 0.565118134021759 0.046622492372989655 43.991099214849214 40.0 1.0 no 15833 chrXVI_900845r 38259 essential YPR183W 93 - TCGGTCTTCTTGGCCATTTC E|38|Q E|38|K K|36|N silent|AAG>AAA|K|36 DPM1 Dolichol Phosphate Mannose synthase 267.0 0 1 0 0 -1.163573459952033 P14020 0.0195743590593338 0.015285116620361803 0.5614444613456726 55.761485393984906 50.0 1.0 no 15834 chrXVI_900939 38264 essential YPR183W 184 + ACAACGTCCGCATCATCGTC Y|62|* silent|TAC>TAT|Y|62 N|63|K silent|AAC>AAT|N|63 DPM1 Dolichol Phosphate Mannose synthase 267.0 0 0 0 0 -0.538992594370374 P14020 0.9362086653709412 52.1928235967336 55.00000000000001 1.0 no 15835 chrXVI_900976 38266 essential YPR183W 221 + TCTATCCTCCGCCGTGCTTA L|75|V silent|CTA>TTA|L|75 S|76|C S|76|F DPM1 Dolichol Phosphate Mannose synthase 267.0 0 0 0 0 -0.03199728587335643 P14020 0.0 0.0 0.0 60.05380694565344 55.00000000000001 1.0 no 15836 chrXVI_901065r 38270 essential YPR183W 313 - AGACTCGAACAACTTGGGCA E|110|D silent|GAG>GAA|E|110 E|110|Q E|110|K DPM1 Dolichol Phosphate Mannose synthase 267.0 0 0 0 0 -0.5149397122779974 P14020 0.6202300190925598 0.5524799823760986 0.8688545823097229 47.032418300083116 50.0 1.0 no 15837 chrXVI_901070r 38271 essential YPR183W 318 - TGCAAAGACTCGAACAACTT L|112|F silent|TTG>TTA|L|112 DPM1 Dolichol Phosphate Mannose synthase 267.0 0 0 0 0 -0.04064966073104179 P14020 0.12318799644708632 39.87708204824214 40.0 1.0 no 15838 chrXVI_901115 38275 essential YPR183W 360 + ACCAGATATGCCCCAGGTGT silent|ACC>ACG|T|121 silent|ACC>ACT|T|121 T|121|S T|121|I DPM1 Dolichol Phosphate Mannose synthase 267.0 0 0 0 0 -0.19841400039595689 P14020 0.6723049283027649 0.008917182683944702 59.27838951822361 55.00000000000001 1.0 no 15839 chrXVI_901127r 38279 essential YPR183W 375 - TCCTTGTCAATGCCGACACC K|131|N silent|AAG>AAA|K|131 D|132|H D|132|N DPM1 Dolichol Phosphate Mannose synthase 267.0 0 0 0 0 0.33986266746585103 P14020 0.07978646457195282 0.03865744173526764 0.4280233979225159 54.758447003424976 55.00000000000001 1.0 no 15840 chrXVI_901179r 38280 essential YPR183W 427 - TCTGGCCATCATTCTAGCAG R|149|T R|149|K A|148|P A|148|T DPM1 Dolichol Phosphate Mannose synthase 267.0 0 0 0 0 -0.4926572580827195 P14020 0.019510438665747643 0.22782765328884125 0.014664147980511187 0.013781887479126452 53.60212967336865 50.0 1.0 no 15841 chrXVI_901211 38281 essential YPR183W 456 + ATCGCCTCCGACCCCATGAG I|153|M silent|ATC>ATT|I|153 A|154|G A|154|V DPM1 Dolichol Phosphate Mannose synthase 267.0 0 0 0 0 0.487724909092585 P14020 0.07189556211233139 0.05793564766645432 1.0 60.58874868286222 65.0 1.0 no 15842 chrXVI_901257 38286 essential YPR183W 502 + ACCTCGAAAACTGCAACCCT L|169|V L|169|F Y|168|* silent|TAC>TAT|Y|168 DPM1 Dolichol Phosphate Mannose synthase 267.0 0 1 0 0 -0.09867668011091058 P14020 0.22421517968177795 1.0 49.101554288017205 50.0 1.0 no 15843 chrXVI_901274 38287 essential YPR183W 519 + CCTAGGGACATCAACTCGCA P|174|R P|174|L DPM1 Dolichol Phosphate Mannose synthase 267.0 0 0 0 0 0.08318550739145539 P14020 0.5826924443244934 0.3906398415565491 52.03511755104637 55.00000000000001 1.0 no 15844 chrXVI_901308r 38289 essential YPR183W 556 - AAGCTTGGCGAGAAGCTCGA K|191|N silent|AAG>AAA|K|191 DPM1 Dolichol Phosphate Mannose synthase 267.0 0 0 0 0 -0.27874658567825705 P14020 0.0 50.343857515499906 55.00000000000001 1.0 no 15845 chrXVI_901345r 38290 essential YPR183W 593 - CTTCGCCGATCGCCACTCTA E|204|Q E|204|K G|203|A G|203|D DPM1 Dolichol Phosphate Mannose synthase 267.0 0 0 0 0 0.3324566780558102 P14020 0.024035206064581868 0.018784446641802788 0.7589241266250609 0.6087664961814879 57.830577535942496 60.0 1.0 no 15846 chrXVI_901346r 38291 essential YPR183W 594 - ACTTCGCCGATCGCCACTCT V|205|L V|205|M E|204|Q E|204|K DPM1 Dolichol Phosphate Mannose synthase 267.0 0 0 0 0 0.6856434284716197 P14020 0.05988375097513199 0.011085400357842444 0.024035206064581868 0.018784446641802788 58.790629102325276 60.0 1.0 no 15847 chrXVI_910188r 38296 essential YPR186C 812 + GCATTATGGGTCTATTCATA H|272|D H|272|Y PZF1 Putative Zinc Finger 429.0 0 0 0 0 -1.697073361330124 P39933 0.9473130106925964 0.9489949941635132 0.0 0.0 45.50299044043521 35.0 0.0 no 15848 chrXVI_910264r 38299 essential YPR186C 736 + ACTCACTAGTAACCAAAAAT S|247|* S|247|L D|246|E silent|GAC>GAT|D|246 PZF1 Putative Zinc Finger 429.0 0 0 0 0 -0.6902458001870007 P39933 0.9298099875450134 0.9532920122146606 0.0012754074996337295 0.031812433153390884 36.34142816217843 30.0 0.0 no 15849 chrXVI_910313 38300 essential YPR186C 690 - AAACCATTTTCCCCCACACA G|236|A G|236|D G|236|R G|236|S PZF1 Putative Zinc Finger 429.0 0 0 0 0 -0.22536427989961275 P39933 0.9499930143356324 0.9446240067481996 0.941340982913971 0.951104998588562 0.7024171948432922 0.3711886405944824 0.5067615509033203 0.8341363668441772 52.699825044061974 45.0 0.0 no 15850 chrXVI_910328 38302 essential YPR186C 675 - ACACATGGTTTGCTACAAAT C|231|S C|231|Y V|232|L V|232|M PZF1 Putative Zinc Finger 429.0 0 0 0 0 -0.9128710061499355 P39933 0.9421560168266296 0.9290120005607604 0.9539830088615416 0.9587630033493042 0.0013904004590585828 0.023318201303482056 0.553657591342926 0.1815932393074036 41.89750397401656 35.0 0.0 no 15851 chrXVI_910424r 38304 essential YPR186C 576 + CCTTACCAATGTACTTTTGC P|193|R P|193|L Y|194|* silent|TAC>TAT|Y|194 PZF1 Putative Zinc Finger 429.0 0 0 0 0 -0.4387320784866959 P39933 0.9432820081710817 0.9430609941482544 0.0008737861644476652 0.0007825155626051128 47.278470506166975 40.0 0.0 no 15852 chrXVI_910455r 38305 essential YPR186C 545 + TTCTAAACATCACGATCCTG S|183|C S|183|F PZF1 Putative Zinc Finger 429.0 0 0 0 0 -0.5937759995614527 P39933 0.945252001285553 0.9294660091400146 0.002703130478039384 0.0033215482253581285 42.41349582452 40.0 0.0 no 15853 chrXVI_910604r 38307 essential YPR186C 396 + TCTTTCATTTGTCCAGAGGA S|133|C S|133|F F|134|L silent|TTC>TTT|F|134 PZF1 Putative Zinc Finger 429.0 0 0 0 0 0.6276276537869382 P39933 0.945252001285553 0.9294660091400146 0.9387490153312684 0.0008446432184427978 0.0009495802223682405 0.013055158779025078 49.304439152021246 40.0 0.0 no 15854 chrXVI_910609 38308 essential YPR186C 394 - CTCTGGACAAATGAAAGATT E|138|Q E|138|K PZF1 Putative Zinc Finger 429.0 0 0 0 0 0.8035611633569743 P39933 0.956179976463318 0.9475290179252625 0.008541011251509191 0.0064677479676902285 36.5095622711869 35.0 0.0 no 15855 chrXVI_910682 38310 essential YPR186C 321 - CCACAATAAGAACATTGGAA C|113|S C|113|Y G|114|R G|114|R PZF1 Putative Zinc Finger 429.0 0 0 0 0 -3.1456132943834887 P39933 0.9421560168266296 0.9290120005607604 0.941340982913971 0.941340982913971 0.0 0.0 0.0007564877741970122 0.0007564877741970122 37.324332029979594 35.0 0.0 yes 15856 chrXVI_910682r 38311 essential YPR186C 318 + CCATTCCAATGTTCTTATTG P|107|R P|107|L F|108|L silent|TTC>TTT|F|108 PZF1 Putative Zinc Finger 429.0 0 0 0 0 0.15892162117749248 P39933 0.9432820081710817 0.9430609941482544 0.9387490153312684 0.0020117009989917283 0.0017571862554177642 0.005517637822777033 44.79086584317429 35.0 0.0 no 15857 chrXVI_910797r 38312 essential YPR186C 203 + ACACCAATTAAGCGTACATC H|69|Q silent|CAC>CAT|H|69 H|69|D H|69|Y PZF1 Putative Zinc Finger 429.0 0 0 0 0 -0.40803976736396175 P39933 0.9588389992713928 0.9473130106925964 0.9489949941635132 0.0 0.0 0.0 43.00609357474059 40.0 0.0 no 15858 chrXVI_910859r 38314 essential YPR186C 141 + ACATATTTCTGTGACTATGA T|48|R T|48|I PZF1 Putative Zinc Finger 429.0 0 0 0 0 0.984163332082222 P39933 0.9476869702339172 0.9472420215606691 0.022456340491771698 0.004231614992022514 40.23733738503813 30.0 0.0 no 15859 chrXVI_910967 38318 essential YPR186C 36 - TCCTGTTTAAGTTCGGCCAG Q|18|H silent|CAG>CAA|Q|18 E|19|Q E|19|K PZF1 Putative Zinc Finger 429.0 0 1 0 0 0.4596472379138413 P39933 0.9570760130882264 0.956179976463318 0.9475290179252625 0.2273105084896088 0.23576286435127256 0.3793639838695526 53.20434764263178 50.0 0.0 no 15860 chrXVI_911581 38322 essential YPR187W 248 + ATACATGACCAAATATGAAA Y|84|* silent|TAC>TAT|Y|84 RPO26 RNA POlymerase 155.0 0 0 0 0 -1.1921133359706548 P20435 33.3298095500424 25.0 1.0 no 15861 chrXVI_911625r 38323 essential YPR187W 295 - CGCATTCATGGAAATTTGTA A|105|P A|105|T M|103|I M|103|I RPO26 RNA POlymerase 155.0 0 1 0 0 -0.6103090094759143 P20435 0.0 0.0 0.015172532759606838 0.015172532759606838 6.033299922943115 1.7640000581741333 1.3012000322341921 1.3012000322341921 7.308239936828612 0.7333999872207642 1.2634999752044678 1.2634999752044678 8.559364318847656 1.3723289966583252 1.5081689357757568 1.5081689357757568 41.21243381049271 35.0 1.0 no 15862 chrXVI_911637r 38325 essential YPR187W 307 - TACAAAAACTGGCGCATTCA V|109|L V|109|I RPO26 RNA POlymerase 155.0 0 0 0 0 0.5581384609744934 P20435 0.0 0.0 0.9845340251922609 -0.4859519898891449 1.3466999530792236 -0.3661200106143952 41.75295751999545 40.0 1.0 no 15863 chrXVI_911648r 38327 essential YPR187W 318 - CCTTCTAAATCTACAAAAAC G|113|R G|113|S E|112|Q E|112|K RPO26 RNA POlymerase 155.0 0 0 0 0 -0.5476183885479814 P20435 0.0 0.0 0.0748215913772583 0.009797018952667713 3.069580078125 3.2117400169372563 -0.41413998603820795 -0.3856000006198883 34.042746241372754 30.0 1.0 no 15864 chrXVI_911681r 38329 essential YPR187W 351 - TCCTTCATGGCAATACGCAA K|123|N silent|AAG>AAA|K|123 E|124|Q E|124|K RPO26 RNA POlymerase 155.0 1 Series([], Name: modification, dtype: object) 0 0 0 -2.8400778058900515 P20435 0.0 0.0 0.0 0.9759399890899658 3.1256380081176762 7.994852066040039 48.53069330358068 45.0 1.0 yes 15865 chrXVI_917585 38330 essential YPR190C 1437 - ACTGGCATTAGTTTGCTATA V|486|L V|486|I M|484|I M|484|I RPC82 RNA Polymerase C 654.0 0 0 0 0 -0.07054908812182467 P32349 0.1331757754087448 1.0 0.2511585354804993 0.2511585354804993 46.09282218071519 35.0 0.0 no 15866 chrXVI_917867 38335 essential YPR190C 1155 - GAACGCTTTTTATTGTCAGA R|391|P R|391|H K|390|N silent|AAG>AAA|K|390 RPC82 RNA Polymerase C 654.0 0 1 0 0 0.16534917391069526 P32349 0.10473714023828506 0.07241343706846237 0.1328742504119873 42.895030817112 35.0 0.0 no 15867 chrXVI_917908 38336 essential YPR190C 1114 - TCCACGCAAGTCCAATTCTG G|378|R G|378|R G|378|A G|378|E RPC82 RNA Polymerase C 654.0 0 0 0 0 -0.4333184423967208 P32349 0.19776315987110135 0.19776315987110135 0.22151416540145874 0.2830178141593933 50.425936712641715 50.0 0.0 no 15868 chrXVI_917910 38338 essential YPR190C 1112 - CACGCAAGTCCAATTCTGCG R|377|P R|377|H L|376|F silent|TTG>TTA|L|376 RPC82 RNA Polymerase C 654.0 0 0 0 0 0.7029357507838848 P32349 0.11500971764326096 0.10493073612451552 0.156150221824646 50.27605932960347 55.00000000000001 0.0 no 15869 chrXVI_918189r 38342 essential YPR190C 830 + AGTCTCTCTGACGATTAATT silent|GTC>GTG|V|278 silent|GTC>GTT|V|278 S|279|C S|279|F RPC82 RNA Polymerase C 654.0 0 0 0 0 0.00794963305476748 P32349 0.1432938426733017 0.26083341240882874 42.70019382450693 35.0 0.0 no 15870 chrXVI_918298 38345 essential YPR190C 724 - ATCAGTTTTCGCATTCATCT D|248|H D|248|N RPC82 RNA Polymerase C 654.0 0 0 0 0 0.2792089345080335 P32349 0.04096129909157753 0.11882645636796953 47.58978147147923 35.0 0.0 no 15871 chrXVI_918304 38346 essential YPR190C 718 - TTTCGCATTCATCTTGGCTT silent|GCG>GCC|A|245 silent|GCG>GCA|A|245 A|245|P A|245|T RPC82 RNA Polymerase C 654.0 0 0 0 0 -0.01632590366713846 P32349 0.053517922759056084 0.6055373549461365 50.85342265102759 40.0 0.0 no 15872 chrXVI_918528r 38352 essential YPR190C 491 + ATCATTAGGGTCCTTAACAG S|165|* S|165|L RPC82 RNA Polymerase C 654.0 0 0 0 0 0.3176410017184229 P32349 0.28844982385635376 45.27709705275874 40.0 0.0 no 15873 chrXVI_918541r 38353 essential YPR190C 478 + TACAAAACGTTATATCATTA Q|161|E Q|161|* RPC82 RNA Polymerase C 654.0 0 0 0 0 0.10227522696039897 P32349 0.2498256266117096 32.251840505979885 20.0 0.0 no 15874 chrXVI_918542r 38354 essential YPR190C 477 + GTACAAAACGTTATATCATT Q|161|E Q|161|* RPC82 RNA Polymerase C 654.0 0 0 0 0 -0.5682905272647576 P32349 0.2498256266117096 34.895444067957555 25.0 0.0 no 15875 chrXVI_918640r 38355 essential YPR190C 379 + TACACATTTTACTCTACTCA H|128|D H|128|Y H|128|Q silent|CAC>CAT|H|128 RPC82 RNA Polymerase C 654.0 0 0 0 0 0.4349351776204957 P32349 0.8224662542343141 0.6730399131774902 0.6429413557052612 41.37796294364585 30.0 0.0 no 15876 chrXVI_918641r 38356 essential YPR190C 378 + ATACACATTTTACTCTACTC H|128|D H|128|Y H|128|Q silent|CAC>CAT|H|128 RPC82 RNA Polymerase C 654.0 0 0 0 0 -0.02988375173420782 P32349 0.8224662542343141 0.6730399131774902 0.6429413557052612 39.96579797470105 30.0 0.0 no 15877 chrXVI_918879r 38360 essential YPR190C 140 + TCTTTACAAAGAGTTGGTGA L|48|V L|48|F Y|49|* silent|TAC>TAT|Y|49 RPC82 RNA Polymerase C 654.0 0 0 0 0 0.5673164993712065 P32349 0.0 0.0 40.84986812014245 35.0 0.0 no 15878 chrXVI_918913 38361 essential YPR190C 109 - ATTCAAGGTTCTCTGTTCCA L|42|F silent|TTG>TTA|L|42 RPC82 RNA Polymerase C 654.0 0 0 0 0 -0.06665734277361385 P32349 0.18574294447898865 50.47000816643549 40.0 0.0 no 15879 chrXVI_918981 38362 essential YPR190C 41 - CGACAGTGCTCTCACCTGTT V|20|L V|20|I RPC82 RNA Polymerase C 654.0 0 0 0 0 0.09374493609843168 P32349 55.74386011386076 55.00000000000001 0.0 no 15880 chrI_175499r 38364 putative_NF CHRI_+_175429_175561_nf 72 - TTTCTGTGGTCGTAAAGACA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.1875379619044235 44.152839895644725 40.0 no 15881 chrI_175513r 38365 putative_NF CHRI_+_175429_175561_nf 86 - GCTCTAATACGGCTTTTCTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.5569182557647885 48.00772074780213 45.0 no 15882 chrII_48675 38366 putative_NF CHRII_-_48648_48765_nf 71 - CACTTATTAGCTTCTTGCTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.17057492039896274 46.071247638256644 35.0 no 15883 chrII_164324 38375 putative_NF CHRII_+_164191_164368_nf 132 + GCCTTTCGCTTGTTCTCCAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2819291505834375 59.10363252366807 50.0 no 15884 chrII_165505r 38379 putative_NF CHRII_-_165436_165607_nf 80 + AACACGAAATAACAAGTTAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.4760616601010066 30.611059327342897 25.0 no 15885 chrII_167386 38385 putative_NF CHRII_-_167320_167464_nf 59 - TTTCAACTCTTAAATTGTCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.30604004746686153 37.77315901248016 25.0 no 15886 chrII_169761r 38388 putative_NF CHRII_-_169701_169806_nf 23 + GGCAACCAAACTCTCAATCC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2349586686085024 48.00985707696185 50.0 no 15887 chrII_171171r 38390 putative_NF CHRII_+_171144_171264_nf 29 - TTTCTCCTAACGCTCGGAAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5606515202164184 48.72855588294942 50.0 no 15888 chrII_201966 38393 putative_NF CHRII_-_201942_202023_nf 38 - TCTCATTAACGTAAAAAGAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.1144061378261827 32.552499913854774 30.0 no 15889 chrII_254843r 38398 putative_NF CHRII_+_254736_254937_nf 109 - ACAGACAAGATGAAACAATT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.8020646044168758 33.53790161221508 30.0 no 15890 chrII_350205 38400 putative_NF CHRII_+_350187_350277_nf 17 + TACGGTTAACATGTATTATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.5818787105668826 36.53083391611176 25.0 no 15891 chrII_366888r 38401 putative_NF CHRII_+_366818_366920_nf 72 - AACATCTGTACTCTATATAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.228621984408387 37.40858664353465 25.0 no 15892 chrII_431091r 38403 putative_NF CHRII_-_431069_431177_nf 64 + TGGCAAGGCATATACCCATT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6092220617276712 50.76184221340418 45.0 no 15893 chrII_556101r 38406 putative_NF CHRII_+_556056_556140_nf 47 - AGCATAAACACTCCAAGGCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.6952524107907134 46.59529070374714 45.0 no 15894 chrII_556064 38408 putative_NF CHRII_+_556056_556140_nf 7 + ATCAATCATCTTATTCCTGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2810783119956851 45.37001144166653 35.0 no 15895 chrII_556106r 38409 putative_NF CHRII_+_556056_556140_nf 52 - GGACAAGCATAAACACTCCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.1458891772308611 44.655510454404926 45.0 no 15896 chrII_718350r 38413 putative_NF CHRII_-_718292_718400_nf 28 + GGCAGAATCACTTTAAAACG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.18160228115266952 38.627759259587656 40.0 no 15897 chrII_785405r 38414 putative_NF CHRII_-_785372_785489_nf 62 + TCGTATTGTAATTGCTTATT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6278723841985814 39.75608732250885 25.0 no 15898 chrII_786673r 38415 putative_NF CHRII_-_786630_786717_nf 22 + AAGCATTTTGTACCATTCAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6474032497227364 43.68268040838336 35.0 no 15899 chrII_799518r 38416 putative_NF CHRII_-_799288_799573_nf 33 + TTACTTGGAGTGACCATTTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.1472581243569009 44.41865974562353 35.0 no 15900 chrII_804710r 38418 putative_NF CHRII_-_804702_804807_nf 75 + GTCTCCTTATACTCTCCAAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.25020845463479 50.77023169110652 45.0 no 15901 chrII_804746 38419 putative_NF CHRII_-_804702_804807_nf 42 - TCTTCCCCACAAAAATTATG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.16838574477101248 41.82732943781855 35.0 no 15902 chrII_804750r 38420 putative_NF CHRII_-_804702_804807_nf 35 + GCCTCCACATAATTTTTGTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.4395419213083024 47.861033311430674 40.0 no 15903 chrIII_29032 38422 putative_NF CHRIII_-_29017_29212_nf 161 - TCTCAAAACCAAATTGCGCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.43592522331878025 42.69989084319161 40.0 no 15904 chrIII_29865r 38424 putative_NF CHRIII_+_29811_29934_nf 56 - CACTGGACAATACAAATCTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4976680764611722 38.31673974605519 35.0 no 15905 chrIII_123439r 38425 putative_NF CHRIII_+_123435_123525_nf 6 - GTACAATAAACCAAGGCGCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.17563878649365952 44.260700394198075 45.0 no 15906 chrIII_155657 38427 putative_NF CHRIII_+_155619_155727_nf 37 + CACAATATCTTATTATTATT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.8553227137703545 32.484042854368404 15.0 no 15907 chrIII_303301r 38429 putative_NF CHRIII_+_303261_303342_nf 42 - TCTTGGTTTTCTCCATTAGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2439992715708198 48.18411522082425 35.0 no 15908 chrIV_50053 38430 putative_NF CHRIV_+_50028_50247_nf 24 + ACACAATACTCCTTGATCGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.950542081082352 44.470189714191854 40.0 no 15909 chrIV_50128 38431 putative_NF CHRIV_+_50028_50247_nf 99 + CCTACTATTTCACCAGTATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.07945055534503342 45.96204081506295 35.0 no 15910 chrIV_50140r 38432 putative_NF CHRIV_+_50028_50247_nf 114 - ATCATAAAACGACCGTATAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.06885566790081132 37.63265702440128 35.0 no 15911 chrIV_56517r 38434 putative_NF CHRIV_+_56495_56585_nf 24 - GCTGTTATTTCTGCGTGTAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.395166962310781 48.21725194345004 40.0 no 15912 chrIV_301240 38435 putative_NF CHRIV_+_301234_301369_nf 5 + TTTCAACAAGTACCCTTCGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7171167307625009 47.62687946255983 40.0 no 15913 chrIV_301278r 38436 putative_NF CHRIV_+_301234_301369_nf 46 - CACAAAGCATCCAGCAAAGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.07703524952720607 44.954046194610214 45.0 no 15914 chrIV_411097r 38438 putative_NF CHRIV_-_411051_411177_nf 58 + GGACCGCTGTCACCTTGCCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9917440057705922 63.6651079001897 65.0 no 15915 chrIV_411115 38439 putative_NF CHRIV_-_411051_411177_nf 43 - GGTCCCCGTCTCCTCCACAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5810511226632471 65.32594223658765 65.0 no 15916 chrIV_413417r 38445 putative_NF CHRIV_+_413380_413482_nf 39 - GTACATCCTTGTCGAGCCTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6401609288593707 55.688426164810494 50.0 no 15917 chrIV_556823r 38450 putative_NF CHRIV_+_556780_556861_nf 45 - TCCTCTATTGATGTTACACC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.2772139348557457 47.94419448825983 40.0 no 15918 chrIV_556808r 38451 putative_NF CHRIV_+_556780_556861_nf 30 - ACACCTGGACACCCCTTTTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.5281653510290826 57.47704100838735 55.00000000000001 no 15919 chrIV_699932 38455 putative_NF CHRIV_+_699922_700099_nf 9 + GCACTCGATCCATATTATCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9032903172769629 47.42218586207662 40.0 no 15920 chrIV_700068 38458 putative_NF CHRIV_+_699922_700099_nf 145 + AGCACGCTGCAGTTGCATCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.0683847285213898 56.702449352421176 55.00000000000001 no 15921 chrIV_720375 38460 putative_NF CHRIV_-_720345_720426_nf 32 - CGCTATCTTTCGTTAGATTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.28905578245066993 44.11297808275674 35.0 no 15922 chrIV_746568r 38462 putative_NF CHRIV_+_746540_746630_nf 30 - ATTCGCCGCGTATACTGCCC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7054592475067498 58.81737355626024 60.0 no 15923 chrIV_924407r 38463 putative_NF CHRIV_-_924330_924432_nf 3 + ACTTCAATACGCACTTCTGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.6678705139606975 46.45491877827925 40.0 no 15924 chrIV_924340r 38465 putative_NF CHRIV_-_924330_924432_nf 70 + TTTCAATAGAGCAAAGCAAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4573763936561137 37.127301454353024 35.0 no 15925 chrIV_976553 38467 putative_NF CHRIV_+_976533_976644_nf 19 + ACAAAGCAGTACAACTGTTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.8632183401673175 40.61430938768791 35.0 no 15926 chrIV_1014314 38468 putative_NF CHRIV_-_1014235_1014376_nf 43 - TCTATTAAAACTGATGTCCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3231424010354373 38.969606319528104 30.0 no 15927 chrIV_1014286r 38469 putative_NF CHRIV_-_1014235_1014376_nf 68 + TCCAAATTCCCAAGGAATTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.025005643926930717 43.56088848629679 40.0 no 15928 chrIV_1174738r 38471 putative_NF CHRIV_-_1174659_1174788_nf 28 + TCTCTTTCTATAATGTTCCC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7117292334008583 47.094846261833545 35.0 no 15929 chrIV_1174734r 38472 putative_NF CHRIV_-_1174659_1174788_nf 32 + TTTCTATAATGTTCCCAGGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.6415604051147226 47.75458369548244 35.0 no 15930 chrIV_1402689 38478 putative_NF CHRIV_-_1402679_1402784_nf 76 - TGGCCATCTATCTGCCATAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6712691845508687 53.739736953117244 45.0 no 15931 chrIV_1402712 38479 putative_NF CHRIV_-_1402679_1402784_nf 53 - TCGTAACACAAAATGCCCAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.13482154080833242 42.35556100669328 40.0 no 15932 chrIV_1402748r 38480 putative_NF CHRIV_-_1402679_1402784_nf 14 + GTTCTTAGGGTTAAATAATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.602330574753565 35.851503485361945 25.0 no 15933 chrIV_1502303r 38486 putative_NF CHRIV_-_1502262_1502361_nf 36 + CACGGTTCCATTATTGCTTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.973375636032126 50.23698326368168 45.0 no 15934 chrIV_1514537 38487 putative_NF CHRIV_-_1514515_1514629_nf 73 - CACAGTATTTTTAGTACTCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.1439444755485823 41.16290195524732 30.0 no 15935 chrIV_1518401 38490 putative_NF CHRIV_-_1518361_1518457_nf 37 - TTCTTTACTGTCATTCAAAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4561727842606766 38.705334689017036 25.0 no 15936 chrV_14590r 38492 putative_NF CHRV_+_14577_14679_nf 15 - ATTCCTATTCTGTATCCATC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.13582261786929806 47.91710232797595 35.0 no 15937 chrV_15915r 38494 putative_NF CHRV_-_15876_15969_nf 32 + TCAAGATGCTCGAGACATTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.375662221844994 43.71717286945585 40.0 no 15938 chrV_136868r 38505 putative_NF CHRV_+_136814_136895_nf 56 - TTTCAAAAATAACCTCAAAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.1810621726245956 31.37921698860106 20.0 no 15939 chrV_156324 38506 putative_NF CHRV_-_156313_156394_nf 51 - TAACTGTGCAGTAATCTTTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4127562242283379 40.87821340430549 30.0 no 15940 chrV_159431 38507 putative_NF CHRV_+_159423_159537_nf 7 + TCATCCTTGCGCTTGTCGCG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.7281989422346403 57.994030603703955 60.0 no 15941 chrV_177488 38510 putative_NF CHRV_-_177402_177537_nf 30 - CTCTGATTTACATTCGAACG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7016060859768439 40.881759955728455 40.0 no 15942 chrV_177487r 38511 putative_NF CHRV_-_177402_177537_nf 28 + CTCGTTCGAATGTAAATCAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6330211749439032 39.554494986120574 40.0 no 15943 chrV_225645 38517 putative_NF CHRV_-_225472_225703_nf 39 - ATCTGTACGATCGTTTCTGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4168481546313467 48.68605195691094 45.0 no 15944 chrV_225673r 38518 putative_NF CHRV_-_225472_225703_nf 8 + TTTCAGTATTGCGGCAAATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5025988835917838 43.026461404626616 35.0 no 15945 chrV_242253 38520 putative_NF CHRV_-_242201_242417_nf 145 - TCCGAGATACAACTTTCCGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.1993780501325801 48.52429315319097 45.0 no 15946 chrV_242269r 38522 putative_NF CHRV_-_242201_242417_nf 126 + TACTACGGTACTTTTCCCCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.1172684532314165 52.98756973798624 45.0 no 15947 chrV_242284r 38523 putative_NF CHRV_-_242201_242417_nf 111 + CTCTCGAAATTACAATACTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5011208285667548 35.997935424719174 30.0 no 15948 chrV_242347 38525 putative_NF CHRV_-_242201_242417_nf 51 - CAACCCTTAGTAAACAGCTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.1622236788416263 44.928860158419006 45.0 no 15949 chrV_242880r 38528 putative_NF CHRV_+_242831_242930_nf 51 - GTGCAAATTATTGCTTCCTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.2246263210310466 46.24540838951742 35.0 no 15950 chrV_248617 38530 putative_NF CHRV_+_248559_248664_nf 57 + ATCAAAAAATTATGTAATAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.7765652554576083 24.85858942952041 10.0 no 15951 chrV_268777 38531 putative_NF CHRV_-_268767_268869_nf 73 - TTCAGAAATTAATATGATTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6078292655287091 29.316495609170037 15.0 no 15952 chrV_301859 38533 putative_NF CHRV_+_301816_301933_nf 42 + ATTCCCCCCTGCCCCGAAAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.17955393696506605 62.53473237171994 60.0 no 15953 chrV_301866r 38537 putative_NF CHRV_+_301816_301933_nf 52 - CCTAGACCCCATTTCGGGGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.6873600230626197 61.34703275647666 65.0 no 15954 chrV_332460r 38540 putative_NF CHRV_-_332449_332566_nf 84 + CTGCCATCGGATAACGTCCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.20803259975163 53.117691659848454 55.00000000000001 no 15955 chrV_359295r 38543 putative_NF CHRV_+_359260_359377_nf 37 - ACTCAAGCGACCAGTGGAAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7096916983567176 48.4617916888642 50.0 no 15956 chrV_359285 38544 putative_NF CHRV_+_359260_359377_nf 24 + AACTCGCCATCCTATTCCAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.11731560438904075 53.42332352455122 50.0 no 15957 chrV_378046 38545 putative_NF CHRV_+_378004_378181_nf 41 + TCCTCAGTATCCCACTCCCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.19460233512182712 62.47955025353832 55.00000000000001 no 15958 chrV_378150 38547 putative_NF CHRV_+_378004_378181_nf 145 + TTCTTATCACAAGAATGTGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7308152608496574 40.38106820867819 35.0 no 15959 chrV_395037r 38549 putative_NF CHRV_-_395039_395132_nf 73 + CCCTCAATATTAATGTGTAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.4724452423840062 41.7505749560886 35.0 no 15960 chrV_395041 38550 putative_NF CHRV_-_395039_395132_nf 72 - TACACATTAATATTGAGGGG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.7691100907507433 38.675162981624 35.0 no 15961 chrV_432043 38551 putative_NF CHRV_-_431996_432092_nf 30 - TCAATTAAAGTTAGACAAGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.7312088152212735 33.280219676634324 25.0 no 15962 chrV_432013r 38552 putative_NF CHRV_-_431996_432092_nf 57 + CTCACAAGAAATGTTTTGCC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.2199413432952748 42.676324505130246 40.0 no 15963 chrV_488413r 38557 putative_NF CHRV_-_488389_488488_nf 53 + AATCACATTTTTATCGCCTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4236449531513541 43.26454926083932 30.0 no 15964 chrVI_36371 38559 putative_NF CHRVI_-_36351_36504_nf 114 - TATCCACGGTCTAAGCACGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.8388852180044214 49.738773406767855 50.0 no 15965 chrVI_97919r 38561 putative_NF CHRVI_-_97880_97991_nf 50 + CACATCATTGTTCGTACTCG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.29023136704102503 46.27800507207729 45.0 no 15966 chrVI_97925 38562 putative_NF CHRVI_-_97880_97991_nf 47 - GTACGAACAATGATGTGTTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.3294603791480736 40.36901707353326 40.0 no 15967 chrVI_97952 38564 putative_NF CHRVI_-_97880_97991_nf 20 - ACCTCGTCAAAACAAGACAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4993768464745568 40.14847247262247 40.0 no 15968 chrVI_111515r 38566 putative_NF CHRVI_-_111447_111594_nf 57 + ACGACTGTTTATTTGCGTAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5389908678243788 44.234282304381 35.0 no 15969 chrVI_111532 38567 putative_NF CHRVI_-_111447_111594_nf 43 - AGTCGTTGTATCATCAATTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.12367383036731301 42.24585285168797 30.0 no 15970 chrVI_111540 38568 putative_NF CHRVI_-_111447_111594_nf 35 - TATCATCAATTTCGGCTGTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.2870852562483513 45.87158665662543 40.0 no 15971 chrVII_14814 38572 putative_NF CHRVII_+_14809_14935_nf 4 + TGGCTGTAGTATCACCGCAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.09591904794494642 54.105102899371154 55.00000000000001 no 15972 chrVII_72603r 38573 putative_NF CHRVII_-_72594_72681_nf 56 + ACATATTAATATGCGATTTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5053658697938461 35.42725672259331 20.0 no 15973 chrVII_149108 38577 putative_NF CHRVII_+_149078_149210_nf 29 + TCGAGTTCCGCCTATGTTAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.15841933146998674 52.87497792471515 50.0 no 15974 chrVII_197768 38579 putative_NF CHRVII_-_197766_197877_nf 90 - CAACAATACGTTTCTTGAGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5276483347667822 41.5219583895181 40.0 no 15975 chrVII_202556 38582 putative_NF CHRVII_+_202495_202585_nf 60 + TTCTCGGTTTATATTTCAAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.2962012463713 40.07819349263031 30.0 no 15976 chrVII_320091r 38583 putative_NF CHRVII_+_320040_320124_nf 53 - ACGAATGCATTCTTTTTGCC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.8288523792047903 47.03586012449779 40.0 no 15977 chrVII_320044r 38584 putative_NF CHRVII_+_320040_320124_nf 6 - TGCAAATCGTACTGTTTTGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.17705388438492453 43.416321162596496 35.0 no 15978 chrVII_320045r 38585 putative_NF CHRVII_+_320040_320124_nf 7 - CTGCAAATCGTACTGTTTTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7559849768336991 42.75714580775736 40.0 no 15979 chrVII_326539r 38588 putative_NF CHRVII_+_326362_326611_nf 179 - TTGCTCCTCCTATCCAAGAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.21725055553007416 51.84233041204868 45.0 no 15980 chrVII_484115r 38589 putative_NF CHRVII_-_484116_484266_nf 129 + AAGCTTGTTCTGTTAGTTTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.013862846805694645 43.781913474947146 30.0 no 15981 chrVII_484175r 38590 putative_NF CHRVII_-_484116_484266_nf 69 + CTCAATAAGTTTGCCGCATT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.8044556601828664 46.675443517275816 40.0 no 15982 chrVII_494237r 38591 putative_NF CHRVII_-_494196_494328_nf 69 + AGACTTGGCCATCTCAAACT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9370016097814567 48.46872428490872 45.0 no 15983 chrVII_494293 38593 putative_NF CHRVII_-_494196_494328_nf 16 - CGCAATATTAATGCTAGAAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9527521248695155 36.937482864219476 35.0 no 15984 chrVII_660207r 38594 putative_NF CHRVII_+_660175_660277_nf 34 - TATCTGCCATTTTAGTATTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7695390031757088 42.97332195674062 25.0 no 15985 chrVII_701999 38596 putative_NF CHRVII_-_701984_702131_nf 113 - TTCGTGCATCAGCTTCTGTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3563844568172051 54.436627892759816 50.0 no 15986 chrVII_702021 38597 putative_NF CHRVII_-_701984_702131_nf 91 - GTTCAATGATTGTTTAATTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9154159824280356 36.19229975067481 25.0 no 15987 chrVII_702083 38598 putative_NF CHRVII_-_701984_702131_nf 29 - CTTCTTGAAAATTCGATGTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.272701671344902 37.08323854631061 30.0 no 15988 chrVII_766598 38600 putative_NF CHRVII_-_766566_766740_nf 123 - TTGCATAGGTACAAAATAAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.5109449977114353 34.58206684014863 30.0 no 15989 chrVII_766606 38601 putative_NF CHRVII_-_766566_766740_nf 115 - GTACAAAATAACCGGATTTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.6133150959391154 37.1863194239034 30.0 no 15990 chrVII_766617r 38602 putative_NF CHRVII_-_766566_766740_nf 101 + ATCGAATCTTACCCAAAATC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.06331510200248608 40.04772142129343 35.0 no 15991 chrVII_766720 38603 putative_NF CHRVII_-_766566_766740_nf 1 - GTACATATCCACAACTCTCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.07216700050352667 46.161361265290786 40.0 no 15992 chrVII_905049 38604 putative_NF CHRVII_-_905034_905118_nf 50 - CTACATGCAAACGACAAATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.14974522531394566 36.46456203660807 35.0 no 15993 chrVII_974260 38605 putative_NF CHRVII_-_974232_974364_nf 85 - ATCGGATAACGCTGCCAACT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.07694741120300297 49.11641404489876 50.0 no 15994 chrVII_996451r 38606 putative_NF CHRVII_-_996442_996535_nf 62 + TGGCTGGTCAAAAATTCTAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.2488999177843949 40.90465945782199 40.0 no 15995 chrVII_1069671 38608 putative_NF CHRVII_-_1069657_1069744_nf 54 - TGACCACCCACAATAAAGCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5405449243720666 46.8404829828537 45.0 no 15996 chrVIII_13244r 38611 putative_NF CHRVIII_-_13207_13300_nf 34 + AACATACTAAAGCACGCTAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.0015611312366377 39.661450607249606 35.0 no 15997 chrVIII_105329 38614 putative_NF CHRVIII_-_105235_105364_nf 16 - GCCAACTACCATTCGACGCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5447495073201358 53.144595179991995 55.00000000000001 no 15998 chrVIII_105330r 38615 putative_NF CHRVIII_-_105235_105364_nf 12 + TCCTTGCGTCGAATGGTAGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.2040104133080324 52.28394441944943 50.0 no 15999 chrVIII_125864 38616 putative_NF CHRVIII_-_125779_125926_nf 43 - ACTTTTGTAGTACGTGTGCC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9099237279675441 50.79636372955889 45.0 no 16000 chrVIII_354478r 38622 putative_NF CHRVIII_-_354461_354548_nf 48 + GAACAAAATAAACAAGATAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.6430931013773715 26.96488783510688 25.0 no 16001 chrVIII_354484 38623 putative_NF CHRVIII_-_354461_354548_nf 45 - TCTTGTTTATTTTGTTCAAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6625712939576209 37.31856748586699 20.0 no 16002 chrVIII_364803 38624 putative_NF CHRVIII_+_364753_364879_nf 49 + AAGCTTTAGCTCTTGGAGTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7601346894928465 47.661591228592386 40.0 no 16003 chrVIII_364790r 38625 putative_NF CHRVIII_+_364753_364879_nf 39 - GCTAAAGCTTTCAATACGTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5944600934973544 41.17059709390196 35.0 no 16004 chrIX_39313r 38627 putative_NF CHRIX_-_39254_39350_nf 15 + CACATAACTAATACTTTACC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.1897077028398041 36.86027827117135 30.0 no 16005 chrIX_93224 38628 putative_NF CHRIX_-_93212_93362_nf 119 - TCTTAAAATAATTGGCATAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.22290743799946008 33.022033724739906 20.0 no 16006 chrIX_93216 38629 putative_NF CHRIX_-_93212_93362_nf 127 - TGCAGATTTCTTAAAATAAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9659013758415024 32.608074580217426 20.0 no 16007 chrIX_93275r 38632 putative_NF CHRIX_-_93212_93362_nf 65 + CCACCGCTTACCTATGACGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.028453512046806 53.5990393835059 55.00000000000001 no 16008 chrIX_127281 38634 putative_NF CHRIX_-_127263_127362_nf 62 - TCTTACCGTTTGAAACGCGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.024252598845192732 48.225962757906416 50.0 no 16009 chrIX_160773r 38636 putative_NF CHRIX_+_160707_160845_nf 68 - TCCTTTTTCTCTCTATTTTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3868441330407909 46.7675618249487 30.0 no 16010 chrIX_356954r 38637 putative_NF CHRIX_+_356909_356990_nf 47 - TCAACTTTCGCTCTCCAACC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9178906283442844 51.8801514059607 50.0 no 16011 chrIX_429184r 38638 putative_NF CHRIX_-_429068_429317_nf 111 + AAACATGTGAGATTTGATCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.5270942636722838 37.53998676126992 30.0 no 16012 chrIX_429142 38639 putative_NF CHRIX_-_429068_429317_nf 156 - CTCTTAGTGCTAAAAGAAAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.20586926936650168 35.22720851129617 30.0 no 16013 chrIX_429143 38640 putative_NF CHRIX_-_429068_429317_nf 155 - TCTTAGTGCTAAAAGAAATT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.1668838714824606 33.720691073341584 25.0 no 16014 chrX_140006 38642 putative_NF CHRX_-_139970_140072_nf 47 - TCAAACTTGAATGTATCAAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.07280957591182037 32.89594684770333 25.0 no 16015 chrX_220947r 38645 putative_NF CHRX_+_220901_220985_nf 48 - TTGCAACCAGCACTTGTCTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.555836854089353 51.42746371717272 50.0 no 16016 chrX_223810r 38646 putative_NF CHRX_+_223786_223891_nf 26 - TTTCTTCGTATGCAGTAATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5954113819485396 41.82678172860688 30.0 no 16017 chrX_223860 38648 putative_NF CHRX_+_223786_223891_nf 73 + AAGCTCACTGTGAGGTTCCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.07164648248167582 53.97502297567161 50.0 no 16018 chrX_433066r 38651 putative_NF CHRX_+_433061_433151_nf 7 - TCTTTTCTTTGCACAATCAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7050443052561388 42.083859667700146 30.0 no 16019 chrX_433089r 38652 putative_NF CHRX_+_433061_433151_nf 30 - TCATTTCCTAGACATTCTCG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.06308088570993432 46.4780498676202 40.0 no 16020 chrX_540251 38654 putative_NF CHRX_-_540175_540289_nf 19 - CGGCTTGCCGCTGAAGATAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9391680509211568 52.44121785836296 55.00000000000001 no 16021 chrX_540173r 38655 putative_NF CHRX_-_540175_540289_nf 94 + CCCAATACATTCCTTCATAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.013966832253877015 45.23621152536776 35.0 no 16022 chrX_667269r 38657 putative_NF CHRX_-_667263_667386_nf 95 + CTCTGCACTTCACAATATCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.2300352025548203 46.14595088377985 40.0 no 16023 chrX_667336 38658 putative_NF CHRX_-_667263_667386_nf 31 - GTCATATTTACTAGGTTTGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.2920920341379866 41.649853034211155 30.0 no 16024 chrX_667337 38659 putative_NF CHRX_-_667263_667386_nf 30 - TCATATTTACTAGGTTTGAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4967570734905947 37.625019816205786 25.0 no 16025 chrX_717308r 38660 putative_NF CHRX_-_717309_717405_nf 75 + AATCATTTGTTGTGCATGTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.44719380627765537 42.64725980111956 30.0 no 16026 chrX_717338r 38663 putative_NF CHRX_-_717309_717405_nf 45 + TCAACCCTTTTCCTGCCAGG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.05963055283132258 58.10180315045409 55.00000000000001 no 16027 chrX_721767 38665 putative_NF CHRX_+_721685_721805_nf 81 + CTCGCGCGTACGCATAATTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.17083620632987345 49.17716189714496 55.00000000000001 no 16028 chrXI_24706 38669 putative_NF CHRXI_+_24689_24794_nf 16 + TCACAGCTGCGGCCCATTTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.296952304500506 58.67040689666778 60.0 no 16029 chrXI_24795r 38672 putative_NF CHRXI_-_24755_24848_nf 31 + ACCAGATTGACTTGGATCCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.1308925331691533 49.73958478183488 45.0 no 16030 chrXI_80737r 38673 putative_NF CHRXI_+_80738_80846_nf 1 - TACACTCCGAAGAGACTCCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2542383554401085 49.15660681914693 50.0 no 16031 chrXI_80801 38674 putative_NF CHRXI_+_80738_80846_nf 62 + GTCTGATAGTTTTAATGCTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.038091428977140386 41.192477767298044 30.0 no 16032 chrXI_137267 38676 putative_NF CHRXI_+_137248_137359_nf 18 + TTGCCGCCATTTCTTTCGAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3076640382530265 54.21144820257439 50.0 no 16033 chrXI_143708 38677 putative_NF CHRXI_+_143702_143801_nf 5 + CGCAGCTCTTTATTCTAAAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.06763905739700278 43.65208693077528 40.0 no 16034 chrXI_159271 38678 putative_NF CHRXI_+_159228_159312_nf 42 + ATTCAATTATGGAACCAGCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.018797283036043888 42.75505123140465 35.0 no 16035 chrXI_286332r 38680 putative_NF CHRXI_-_286273_286366_nf 12 + TCATCAAAAGCATATTTTAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7401542617705665 34.305997854160864 20.0 no 16036 chrXI_306880r 38681 putative_NF CHRXI_-_306854_306950_nf 48 + TTACAAGGCGAGCCATTTCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6903087063103617 49.75385882616018 45.0 no 16037 chrXI_306914r 38682 putative_NF CHRXI_-_306854_306950_nf 14 + TACAAAACTTATAAGCTACC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.8484987554498072 35.81689806678264 30.0 no 16038 chrXI_308672 38684 putative_NF CHRXI_-_308594_308747_nf 56 - TCAATACAAAGTCCAAGGAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5773478375350756 38.08292565838258 35.0 no 16039 chrXI_308684r 38686 putative_NF CHRXI_-_308594_308747_nf 41 + TCCTGTGGCACACCTTTCCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.32554875345983875 60.975777279115896 55.00000000000001 no 16040 chrXI_340919 38687 putative_NF CHRXI_+_340884_340998_nf 34 + CCAACTCTAAACATCTTCCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.2311461605276003 45.246965733379795 40.0 no 16041 chrXI_340936r 38688 putative_NF CHRXI_+_340884_340998_nf 54 - TCTTCGTTTTTGAACAGCCG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.3736498308541427 48.14138582974789 45.0 no 16042 chrXI_340961 38690 putative_NF CHRXI_+_340884_340998_nf 76 + TCTTACCCCTCTGCGGCTTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6252889535885688 60.43670127190006 55.00000000000001 no 16043 chrXI_340968r 38691 putative_NF CHRXI_+_340884_340998_nf 86 - ACAGAGCCCTTAAGCCGCAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.53992500203686 56.72497343972413 60.0 no 16044 chrXI_355331 38692 putative_NF CHRXI_-_355277_355400_nf 50 - TCGCGCTGTTCCTCTGTGAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.36808863871112335 58.385990632119615 60.0 no 16045 chrXI_355296r 38694 putative_NF CHRXI_-_355277_355400_nf 82 + ACAAAATTATAAGGTTTCTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.04820583608606607 33.626270473529075 25.0 no 16046 chrXI_533748r 38696 putative_NF CHRXI_-_533733_533838_nf 68 + TTCACCCTCTTTTAACCCAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.12469942569071844 52.77863957008299 45.0 no 16047 chrXI_533796r 38698 putative_NF CHRXI_-_533733_533838_nf 20 + AGGCCCTAGATCGGCGTTTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.3591930720112804 57.953921597907375 55.00000000000001 no 16048 chrXI_533793 38699 putative_NF CHRXI_-_533733_533838_nf 26 - AAACCCAAAACGCCGATCTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6333687990300076 44.85591161091793 45.0 no 16049 chrXI_533807 38701 putative_NF CHRXI_-_533733_533838_nf 12 - GATCTAGGGCCTGCGACGCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.7669300788272451 58.86957049525444 65.0 no 16050 chrXI_552701 38702 putative_NF CHRXI_+_552678_552759_nf 22 + TCAATATTGTTGGCAATTCG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.013102750111884777 40.93891589722847 35.0 no 16051 chrXI_615554 38705 putative_NF CHRXI_+_615532_615625_nf 21 + TTTCCGTTTGTGTCTATTTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.15710293565532274 47.05522036591685 30.0 no 16052 chrXI_626401 38706 putative_NF CHRXI_-_626281_626491_nf 71 - CCTTATTTACTCCCATTAGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.44681854293791495 50.226210173571474 40.0 no 16053 chrXI_626413r 38707 putative_NF CHRXI_-_626281_626491_nf 56 + TTTCTGCGTTACCCAGCTAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.22469307376082934 52.344038791262456 45.0 no 16054 chrXI_626401r 38709 putative_NF CHRXI_-_626281_626491_nf 68 + CCAGCTAATGGGAGTAAATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.8306962366858096 42.381231491066046 40.0 no 16055 chrXI_626412r 38710 putative_NF CHRXI_-_626281_626491_nf 57 + TTCTGCGTTACCCAGCTAAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.3755321705528812 52.05655452612706 45.0 no 16056 chrXII_94389 38713 putative_NF CHRXII_+_94321_94414_nf 67 + ACTCAACACACCTACATGAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4672795076436617 42.89803304832122 40.0 no 16057 chrXII_94395 38714 putative_NF CHRXII_+_94321_94414_nf 73 + CACACCTACATGAAAGGTAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.7852953386464694 40.97203992464813 40.0 no 16058 chrXII_95187 38715 putative_NF CHRXII_-_95156_95279_nf 73 - TCGACGGTATAGATGAATAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.0881764266942593 37.63381987773107 35.0 no 16059 chrXII_164290 38716 putative_NF CHRXII_+_164257_164365_nf 32 + AAACGCGATAATTATAGGCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.19254371723835934 39.174346522525184 35.0 no 16060 chrXII_260649r 38718 putative_NF CHRXII_-_260616_260724_nf 53 + TTTCTTTTTCCTGTCAAGTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3747632263014448 46.531186225258246 30.0 no 16061 chrXII_260676r 38719 putative_NF CHRXII_-_260616_260724_nf 26 + ACATACACTGGTATTCCCTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6842967288060385 49.84801133898714 40.0 no 16062 chrXII_320525 38720 putative_NF CHRXII_+_320426_320558_nf 98 + TCCTTGTTTCTTTGTTTCTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.06271759098096101 49.066486927282604 30.0 no 16063 chrXII_320482 38721 putative_NF CHRXII_+_320426_320558_nf 55 + AACATATGCATATATGTGTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.120931148735489 37.80606445487643 30.0 no 16064 chrXII_373051 38722 putative_NF CHRXII_-_373007_373088_nf 18 - AACTCAATTACAAAGTAAAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.31921012017616235 29.72093818552173 25.0 no 16065 chrXII_373008 38723 putative_NF CHRXII_-_373007_373088_nf 61 - TTACGTATATAGTTGTATAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.0078957764346874 35.39264625833545 25.0 no 16066 chrXII_373711r 38724 putative_NF CHRXII_+_373694_373778_nf 19 - TACTGAAAGTGTTCCTATTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5813904989298679 41.03627556199525 30.0 no 16067 chrXII_373727 38725 putative_NF CHRXII_+_373694_373778_nf 32 + TTCAGTACTATACAGAACTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.17020360294482895 37.989736308798115 30.0 no 16068 chrXII_449235 38726 putative_NF CHRXII_-_449210_449297_nf 43 - ATCTTCTGATAGAATTTCTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.003376134577486977 38.537991618931976 30.0 no 16069 chrXII_498671 38727 putative_NF CHRXII_-_498624_498708_nf 18 - TTACCTCCGTGCATCCTGTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -2.402620820339439 57.06688860985803 50.0 yes 16070 chrXII_498628r 38728 putative_NF CHRXII_-_498624_498708_nf 58 + ACTTCTCGTTCATTAACCCC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4000965352863656 51.789900231604 45.0 no 16071 chrXII_498677r 38729 putative_NF CHRXII_-_498624_498708_nf 9 + CCAATTCCTTACAGGATGCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.093005899932664 49.65350539117037 45.0 no 16072 chrXII_573308 38731 putative_NF CHRXII_-_573290_573449_nf 122 - TGTCTGAACTTTCTCCAGCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.4904573660371625 51.87798520217564 45.0 no 16073 chrXII_669261 38734 putative_NF CHRXII_+_669208_669313_nf 52 + CCTCTAGAGAGACACGCAAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.9474741994373621 47.79244775185639 55.00000000000001 no 16074 chrXII_669212 38735 putative_NF CHRXII_+_669208_669313_nf 3 + CCTGTCACCACAATAGAAAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9700975474866024 41.974187774548 40.0 no 16075 chrXII_781581r 38737 putative_NF CHRXII_-_781522_781633_nf 30 + CAACTGTTGAAAAAAATAGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.4697819487840786 29.24433773480206 25.0 no 16076 chrXII_830484 38739 putative_NF CHRXII_+_830481_830664_nf 2 + GACGTATCTGTGCATTGATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6947414100515592 45.2738652191253 40.0 no 16077 chrXII_830507r 38741 putative_NF CHRXII_+_830481_830664_nf 28 - TCTGCTTTCTGAAACCATGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.35845367131719913 48.17190696236372 45.0 no 16078 chrXII_830530 38742 putative_NF CHRXII_+_830481_830664_nf 48 + GCGGGACGATTCCAAATTAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.08409902005362035 45.95879917497183 50.0 no 16079 chrXII_932602r 38747 putative_NF CHRXII_+_932587_932704_nf 17 - GCGCTGATAGCATTACACAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.10954307562008253 48.8482565356602 50.0 no 16080 chrXII_1001976r 38749 putative_NF CHRXII_-_1001925_1002039_nf 41 + TAGCCCTAGGACAACTTGTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4212658202048057 49.704759733895465 45.0 no 16081 chrXII_1001973 38750 putative_NF CHRXII_-_1001925_1002039_nf 47 - ATACCCTACAAGTTGTCCTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.4917259176934409 49.74333313439036 40.0 no 16082 chrXII_1001978 38751 putative_NF CHRXII_-_1001925_1002039_nf 42 - CTACAAGTTGTCCTAGGGCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.1325093618414062 52.897977144802674 50.0 no 16083 chrXII_1001989r 38752 putative_NF CHRXII_-_1001925_1002039_nf 28 + TTTCCCGATATCCTAGCCCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.18276609722209344 58.758865494281785 50.0 no 16084 chrXII_1058774r 38753 putative_NF CHRXII_-_1058725_1058905_nf 109 + GTACAATGTTGTTATTATGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4131727194668196 38.322393706189864 25.0 no 16085 chrXIII_26819 38755 putative_NF CHRXIII_+_26809_26890_nf 9 + CCTACCCTAAATTGTGATTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.5292285760982081 44.38890290451753 35.0 no 16086 chrXIII_26850 38756 putative_NF CHRXIII_+_26809_26890_nf 40 + TCTTTTTGAATAAATACAAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.12470182902376488 29.96615086827109 15.0 no 16087 chrXIII_164297r 38758 putative_NF CHRXIII_-_164233_164344_nf 25 + TCTCTTTTTCTCAAACTCTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.34831407812923193 43.17557783782291 30.0 no 16088 chrXIII_164665r 38759 putative_NF CHRXIII_+_164622_164730_nf 45 - GAACTGAAAAAATCTCTTAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.328591814109552 30.42517085633085 25.0 no 16089 chrXIII_262911r 38764 putative_NF CHRXIII_+_262848_262962_nf 65 - TCTGGACACTGAATAAACAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.13079853943936895 36.72173069378886 35.0 no 16090 chrXIII_262921 38765 putative_NF CHRXIII_+_262848_262962_nf 72 + TTCAGTGTCCAGATCATATG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4727739794107114 46.13031631541918 40.0 no 16091 chrXIII_262929r 38766 putative_NF CHRXIII_+_262848_262962_nf 83 - TACACATCCCGCATATGATC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7508021652541894 48.475885592388465 45.0 no 16092 chrXIII_279793r 38767 putative_NF CHRXIII_-_279730_279820_nf 5 + CACAATTAGTTATCTTTACA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.1037021423311891 37.17123229063594 25.0 no 16093 chrXIII_279732 38768 putative_NF CHRXIII_-_279730_279820_nf 69 - TAACCCTTGATAAGATTTGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.31234572484776313 39.80754712188184 30.0 no 16094 chrXIII_434129 38771 putative_NF CHRXIII_-_434089_434206_nf 58 - TGACAAAGGGTTCTTGCGCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.90690300957875 49.50724580023712 50.0 no 16095 chrXIII_480966 38772 putative_NF CHRXIII_+_480932_481187_nf 33 + CCAAAGCACGACTATCTGAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.0298216765045622 45.3510236575325 50.0 no 16096 chrXIII_481064r 38776 putative_NF CHRXIII_+_480932_481187_nf 134 - TGTCTACATCAACAAAAGTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5923915506002989 36.04528155275977 30.0 no 16097 chrXIII_481140 38777 putative_NF CHRXIII_+_480932_481187_nf 207 + CGGCGCTCATCCTCATCCAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.11598177159881815 60.305721696853425 65.0 no 16098 chrXIII_481150r 38778 putative_NF CHRXIII_+_480932_481187_nf 220 - TTCTTCATTGCCTGTGGATG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.8226780799943211 50.76751269159415 45.0 no 16099 chrXIII_481156r 38779 putative_NF CHRXIII_+_480932_481187_nf 226 - AGCGTGTTCTTCATTGCCTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.7171748826585789 54.79285938680215 50.0 no 16100 chrXIII_493897r 38780 putative_NF CHRXIII_+_493892_493994_nf 7 - AAACACAAACGAGAGTACAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.2298903138578633 34.539842338825174 35.0 no 16101 chrXIII_556778r 38781 putative_NF CHRXIII_-_556676_556892_nf 92 + TCTATTTTCATTCTCCTTCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6273805043445511 47.58926890465068 30.0 no 16102 chrXIII_782380 38782 putative_NF CHRXIII_-_782332_782425_nf 26 - TAACAACCGTTTCTGATCCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4649245653017861 46.47858703497792 40.0 no 16103 chrXIII_782397r 38784 putative_NF CHRXIII_-_782332_782425_nf 6 + AAGCTTCTGTATACGATCCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6927398873175856 46.70718499753718 40.0 no 16104 chrXIII_837066 38787 putative_NF CHRXIII_+_837033_837171_nf 32 + TGCTAAGCTCCCTTCGGGCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6219469848345885 60.43539276515173 60.0 no 16105 chrXIV_104416r 38790 putative_NF CHRXIV_+_104407_104527_nf 11 - ACAAACGCAGCTCATATTTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.09636307993186816 42.73475682045779 35.0 no 16106 chrXIV_104412r 38791 putative_NF CHRXIV_+_104407_104527_nf 7 - ACGCAGCTCATATTTTGGGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.08849257604661584 51.36089533651369 45.0 no 16107 chrXIV_104417r 38792 putative_NF CHRXIV_+_104407_104527_nf 12 - AACAAACGCAGCTCATATTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.21099906498563809 41.13823610265035 35.0 no 16108 chrXIV_104411r 38793 putative_NF CHRXIV_+_104407_104527_nf 6 - CGCAGCTCATATTTTGGGTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.1948112084245368 50.32350754108632 45.0 no 16109 chrXIV_174582r 38798 putative_NF CHRXIV_-_174520_174613_nf 9 + ACATATCAAAAGTCAGTACT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9869150247616908 37.31432334147723 30.0 no 16110 chrXIV_200302 38799 putative_NF CHRXIV_+_200270_200381_nf 31 + GTCAAATAGCATGCAATCGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.4671588418616795 44.7565502103576 45.0 no 16111 chrXIV_237930r 38804 putative_NF CHRXIV_-_237862_237961_nf 9 + CTACTTTTTACTATCTACGG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3782348428365396 41.279085902208244 35.0 no 16112 chrXIV_237929r 38805 putative_NF CHRXIV_-_237862_237961_nf 10 + TACTTTTTACTATCTACGGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.8846449183653302 43.09830357014528 35.0 no 16113 chrXIV_478319 38812 putative_NF CHRXIV_-_478288_478402_nf 64 - CCACGAACAAAACGCCGCTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.1609153906144225 48.81126487269898 60.0 no 16114 chrXIV_478364 38815 putative_NF CHRXIV_-_478288_478402_nf 19 - ATCATAAATCAGCACGCAAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6338996497905469 39.40275630519875 35.0 no 16115 chrXIV_525671r 38816 putative_NF CHRXIV_+_525614_525695_nf 59 - ATCTGAAAAATCTGCACATT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.20424170032940955 37.42002705188953 30.0 no 16116 chrXIV_542166 38817 putative_NF CHRXIV_+_542126_542237_nf 39 + ACCGTATTTACTTCTACTTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.026876771107746264 44.244403674269726 30.0 no 16117 chrXIV_542200r 38819 putative_NF CHRXIV_+_542126_542237_nf 76 - TTTCTTGTTCGAGCCAGCAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.109570853669304 53.158440946353494 45.0 no 16118 chrXIV_647084 38821 putative_NF CHRXIV_-_647075_647159_nf 56 - TTCTCGTCATCAGGTTGTAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.4708558617022472 49.23932322093452 40.0 no 16119 chrXIV_716462r 38822 putative_NF CHRXIV_+_716395_716578_nf 69 - TCTTCTGTGCTAGGAAACGG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3901591512493021 47.18838501887285 50.0 no 16120 chrXIV_716522 38823 putative_NF CHRXIV_+_716395_716578_nf 126 + TCTCTTTTTCTTTTCTGCCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9242088478356648 52.29691107725751 35.0 no 16121 chrXIV_769840 38827 putative_NF CHRXIV_+_769790_769880_nf 49 + ACAGCGTAATAATGTTCATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6387580057697457 38.977112649081505 30.0 no 16122 chrXV_9141 38832 putative_NF CHRXV_+_9105_9249_nf 35 + AACTACAGTTACTCAGTTAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7885952481673848 40.10752873846917 35.0 no 16123 chrXV_22175r 38835 putative_NF CHRXV_+_22090_22207_nf 87 - CAGCCACATTTATCTAAGGG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.4449919120589771 46.69145422789803 45.0 no 16124 chrXV_22178r 38836 putative_NF CHRXV_+_22090_22207_nf 90 - CTGCAGCCACATTTATCTAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.3197980762426516 47.29015678064325 40.0 no 16125 chrXV_22179r 38837 putative_NF CHRXV_+_22090_22207_nf 91 - ACTGCAGCCACATTTATCTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5972179217339704 49.37600029175064 40.0 no 16126 chrXV_22421r 38838 putative_NF CHRXV_+_22359_22467_nf 64 - ACGACATATATCTGGTAGTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2354085803530958 42.468312385648346 40.0 no 16127 chrXV_38913r 38839 putative_NF CHRXV_+_38888_39047_nf 27 - TCGAAAATTTGACTCAGGGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9220855233617656 41.890182676509596 40.0 no 16128 chrXV_83594r 38843 putative_NF CHRXV_-_83453_83639_nf 23 + CTCTTCTGGCGCCTGTCCCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.6101758556467454 65.92623450506653 65.0 no 16129 chrXV_253001r 38847 putative_NF CHRXV_+_252935_253037_nf 68 - TTTCTTTTATGAAGTGAATG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2517890751526993 34.69107897594057 25.0 no 16130 chrXV_252945 38848 putative_NF CHRXV_+_252935_253037_nf 9 + GGCAATTTAAAAGCTGTCTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.0204605998875655 41.43055307370503 40.0 no 16131 chrXV_299031 38850 putative_NF CHRXV_-_299015_299126_nf 76 - TCCGTTTTTATTCCGACAAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4913936619752361 46.02358078643732 40.0 no 16132 chrXV_299029 38851 putative_NF CHRXV_-_299015_299126_nf 78 - TTTCCGTTTTTATTCCGACA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4826570235536279 47.95327611907482 35.0 no 16133 chrXV_386342 38858 putative_NF CHRXV_-_386278_386398_nf 37 - CAACCTATAAAATTTCCGTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7595070076370559 39.488358047665656 30.0 no 16134 chrXV_386341 38859 putative_NF CHRXV_-_386278_386398_nf 38 - ACAACCTATAAAATTTCCGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.11061190730493208 39.65107620883288 30.0 no 16135 chrXV_401295 38862 putative_NF CHRXV_-_401261_401381_nf 67 - CACTTTCACTGTACAATGCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.19069406602842776 45.04676719340273 40.0 no 16136 chrXV_401401r 38863 putative_NF CHRXV_+_401313_401451_nf 90 - AACAACATTTCAGAAGGGCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2318848164169721 42.20304947208609 40.0 no 16137 chrXV_418322 38868 putative_NF CHRXV_+_418189_418375_nf 132 + ACAGACCATGCTTTTTCTCC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.17284359057490434 52.1845733515973 45.0 no 16138 chrXV_418227 38870 putative_NF CHRXV_+_418189_418375_nf 37 + CCAAATTTGATTTTAAGTTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7711319634274183 35.35795140063413 20.0 no 16139 chrXV_520129r 38871 putative_NF CHRXV_-_520025_520160_nf 9 + GCACTATCACTAGACATCAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.25958912430084025 43.70233556032901 40.0 no 16140 chrXV_520072 38872 putative_NF CHRXV_-_520025_520160_nf 69 - GCATTTATTCTTTTGTGGTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.06087017861300344 44.90268774321918 30.0 no 16141 chrXV_619195r 38874 putative_NF CHRXV_+_619136_619409_nf 61 - GCAACTTATCCTGTGCTCGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4719810725486951 52.60020388766703 50.0 no 16142 chrXV_619306r 38879 putative_NF CHRXV_+_619136_619409_nf 172 - TTTCAGTCCACTCGTTCCGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9147436207306876 56.89517268284653 50.0 no 16143 chrXV_619333 38880 putative_NF CHRXV_+_619136_619409_nf 196 + AGACTGCCCCTCTCTTTCCG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.1021310561056036 61.52287737422245 60.0 no 16144 chrXV_619384 38886 putative_NF CHRXV_+_619136_619409_nf 247 + TTTCAGATTTACTAAGACTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9885876502437718 37.6884066765831 30.0 no 16145 chrXV_642497 38887 putative_NF CHRXV_+_642444_642531_nf 52 + TTCAAACTTCATCATCAGAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.1952850891681699 38.00557533442787 30.0 no 16146 chrXV_642495r 38888 putative_NF CHRXV_+_642444_642531_nf 53 - TTTCTGATGATGAAGTTTGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.16535203586530162 38.81975533566794 30.0 no 16147 chrXV_690276 38889 putative_NF CHRXV_+_690272_690497_nf 3 + ACCGTCGATTATATTCTGAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6408162836209563 44.554531115966036 40.0 no 16148 chrXV_690277r 38890 putative_NF CHRXV_+_690272_690497_nf 7 - TCCTGTCAGAATATAATCGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.245103931919128 41.33887035422964 35.0 no 16149 chrXV_690444 38892 putative_NF CHRXV_+_690272_690497_nf 171 + CCAAACGACACTAAAAGAAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.7142731218926957 34.90452275921831 40.0 no 16150 chrXV_762197r 38895 putative_NF CHRXV_-_762175_762292_nf 73 + CTACTATTAATAAGCACCTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2550423256392492 39.675469266582866 35.0 no 16151 chrXV_762199r 38897 putative_NF CHRXV_-_762175_762292_nf 71 + ACCTACTATTAATAAGCACC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.41973219488558017 42.058581441534216 35.0 no 16152 chrXV_762272 38901 putative_NF CHRXV_-_762175_762292_nf 1 - ACTCTGAAACAATAGAATCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.4564115440877946 34.83704490288721 30.0 no 16153 chrXV_836570 38903 putative_NF CHRXV_-_836551_836662_nf 73 - CAACCTATAACTTTCCATAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.8834093152697338 41.50803597956292 35.0 no 16154 chrXV_949452 38905 putative_NF CHRXV_-_949429_949528_nf 57 - GCACTAAAAACCGCTAACAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4504871857135772 41.080438004896216 40.0 no 16155 chrXV_970117 38908 putative_NF CHRXV_+_970104_970266_nf 12 + TATCACGACAAGCCCAATTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5851172260038013 45.68534515791458 40.0 no 16156 chrXV_970129r 38909 putative_NF CHRXV_+_970104_970266_nf 27 - GCTGCATCTCGACCAAAATT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6342666344595864 46.95551170590875 45.0 no 16157 chrXV_970180 38911 putative_NF CHRXV_+_970104_970266_nf 75 + TCGTTTGATTCGTATATGAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.04181706241647365 40.79836092295557 30.0 no 16158 chrXV_970171r 38912 putative_NF CHRXV_+_970104_970266_nf 69 - TACGAATCAAACGAATGCTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3877237743344519 37.51895023887789 35.0 no 16159 chrXV_978578 38917 putative_NF CHRXV_+_978479_978608_nf 98 + CCATTGTACGGTTCGTACGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.1183961244148802 51.532242684341725 50.0 no 16160 chrXV_978578r 38918 putative_NF CHRXV_+_978479_978608_nf 101 - CCCACGTACGAACCGTACAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.4545435551965733 49.92697380279975 55.00000000000001 no 16161 chrXV_1064813r 38921 putative_NF CHRXV_+_1064815_1064905_nf 0 - GCCTTTATGACATACACCAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.09838340362358113 48.146790199268025 40.0 no 16162 chrXV_1064865 38922 putative_NF CHRXV_+_1064815_1064905_nf 49 + TCACTTCATTGTCAGCAACA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.15777716355406626 46.76523417538011 40.0 no 16163 chrXV_1064866 38923 putative_NF CHRXV_+_1064815_1064905_nf 50 + CACTTCATTGTCAGCAACAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5081516246396167 45.78990655673671 45.0 no 16164 chrXVI_198588r 38925 putative_NF CHRXVI_-_198584_198767_nf 157 + ACAGTGGGATTCCACCATCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3321995557199089 53.91836810173271 50.0 no 16165 chrXVI_198641r 38926 putative_NF CHRXVI_-_198584_198767_nf 104 + TGTCTTTCTTCCAACTGCCG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9396271248028653 53.59888741751746 50.0 no 16166 chrXVI_198672 38928 putative_NF CHRXVI_-_198584_198767_nf 76 - CCTCATTCGGCGTGTATTAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.104189617614907 50.99431951049826 45.0 no 16167 chrXVI_198731 38931 putative_NF CHRXVI_-_198584_198767_nf 17 - GTCTTTTGAATTTGTCAATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4769665455725892 38.0663678672081 25.0 no 16168 chrXVI_210946 38934 putative_NF CHRXVI_+_210875_210965_nf 70 + GGCAACTAACACTATCTTAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3652238308152289 39.92345071636288 35.0 no 16169 chrXVI_215812r 38938 putative_NF CHRXVI_+_215744_215837_nf 70 - GTCAGTATGGACATCTCCGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.1273587125496253 54.362262171730954 55.00000000000001 no 16170 chrXVI_297157 38943 putative_NF CHRXVI_+_297125_297293_nf 31 + AAACACCACTTCTCGGTCCG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.08531347046336779 51.403977220753795 55.00000000000001 no 16171 chrXVI_297174r 38945 putative_NF CHRXVI_+_297125_297293_nf 51 - TTTCCTTCGGTTGATGTCCG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.8814092009207657 53.67349225309084 50.0 no 16172 chrXVI_297219 38946 putative_NF CHRXVI_+_297125_297293_nf 93 + TATCCGCGCCAATCCCTTCG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.14577353510562488 57.84770469948836 60.0 no 16173 chrXVI_297255 38950 putative_NF CHRXVI_+_297125_297293_nf 129 + GCTTTATCTCCGCTTAGCCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4353822691575367 57.67103058122546 50.0 no 16174 chrXVI_297265 38951 putative_NF CHRXVI_+_297125_297293_nf 139 + CGCTTAGCCAAGGCCGTCAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.309284781049466 56.34984270546062 60.0 no 16175 chrXVI_444144 38953 putative_NF CHRXVI_-_444110_444248_nf 85 - TCTTACGACAATACTAATTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2167761826090132 34.837751961522194 25.0 no 16176 chrXVI_444169r 38954 putative_NF CHRXVI_-_444110_444248_nf 57 + TACTGTTCTCTCTTTGTTCG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6208398755057913 47.929952060478975 40.0 no 16177 chrXVI_503339r 38958 putative_NF CHRXVI_+_503247_503370_nf 94 - CTTCACGCTACATGCTTTCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5464730970646078 50.8215017929993 45.0 no 16178 chrXVI_620182r 38963 putative_NF CHRXVI_+_620148_620238_nf 36 - TTGCGAAACCAATTGATTAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6192568962760209 38.569897270103134 35.0 no 16179 chrXVI_828400r 38964 putative_NF CHRXVI_+_828395_828509_nf 7 - GCATTTCACGAGTGTGTAAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.30339454144881683 45.914719907048436 45.0 no 16180 chrXVI_828409 38965 putative_NF CHRXVI_+_828395_828509_nf 13 + CACTCGTGAAATGCACTTCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.16465793214258392 45.43791852082444 45.0 no 16181 chrXVI_828412 38966 putative_NF CHRXVI_+_828395_828509_nf 16 + TCGTGAAATGCACTTCAAGG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.22424646792195296 42.939219471240726 45.0 no 16182 chrXVI_840350r 38969 putative_NF CHRXVI_+_840274_840424_nf 78 - CTCACTGATTTCACCCAAAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.4444232257788495 46.37165886206839 45.0 no 16183 chrXVI_840351r 38970 putative_NF CHRXVI_+_840274_840424_nf 79 - GCTCACTGATTTCACCCAAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.044793850426025975 49.43991129183002 45.0 no 16184 chrXVI_840383r 38971 putative_NF CHRXVI_+_840274_840424_nf 111 - GCGGCAATGTCTTCGCCCAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.20242235274628848 57.61094750408364 60.0 no 16185 chrXVI_860604 38973 putative_NF CHRXVI_+_860530_860692_nf 73 + CACTAGTTATCCGACTAGCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.4922221113689814 48.55705036921329 45.0 no 16186 chrXVI_860614r 38974 putative_NF CHRXVI_+_860530_860692_nf 86 - TGACTAGTTGCCTTGCTAGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2058259705588224 52.59479546026745 45.0 no 16187 chrXVI_927547 38975 putative_NF CHRXVI_-_927492_927588_nf 22 - AGCAACCCCCCGATTTTTGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4124474408582158 57.045988563050564 50.0 no 16188 chrXVI_928753 38978 putative_NF CHRXVI_+_928731_928833_nf 21 + GGCACCAACATTCCACAGCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.1846797497406108 55.112890718573674 55.00000000000001 no 16189 chrXVI_928801 38979 putative_NF CHRXVI_+_928731_928833_nf 69 + TCAAGATTTGTTACTACGTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.042228716504537 39.92480639020772 35.0 no 16190 chrXVI_937057r 38980 putative_NF CHRXVI_+_937058_937208_nf 1 - CCTTCGTATGGACGTATCCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3104082999359369 52.354284462392066 50.0 no 16191 chrXVI_937175r 38982 putative_NF CHRXVI_+_937058_937208_nf 119 - TGTCATGATGTTCACAATAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.40369635427524136 38.48964278038437 30.0 no 16192 chrXVI_937835r 38983 putative_NF CHRXVI_-_937724_937862_nf 5 + CAACAAATTGGGAAGGCAAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.00937304697764202 39.095563201418656 45.0 no 16193 chrI_142385 38984 intron YAL003W_intron 131 + TCTTTGGTCCGTGTTTATGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6327082462625604 49.971258310524426 40.0 no 16194 chrI_142308 38985 intron YAL003W_intron 54 + TTTCCTATGGTTACATGTAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.11670696985788165 42.62598406985831 30.0 no 16195 chrI_142419r 38987 intron YAL003W_intron 168 - TCTCTTTTGTCACTCATATC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.7093650246930892 45.52074682032514 35.0 no 16196 chrI_142420r 38989 intron YAL003W_intron 169 - ATCTCTTTTGTCACTCATAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4991740823076861 44.40998729641456 30.0 no 16197 chrI_151057r 38990 intron YAL001C_intron 17 + TCTCCTTTTCGGCTCCGTTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.32515175409445857 58.72984829207627 50.0 no 16198 chrII_45789 38992 intron YBL092W_intron 144 + GCAAGCTCGTATTTGTTTAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.3653194795462509 45.875326480902636 40.0 no 16199 chrII_45827r 38993 intron YBL092W_intron 185 - TCTGCCACTGTCTCTTTGAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.5492763806461585 53.523272215145596 45.0 no 16200 chrII_45868r 38994 intron YBL092W_intron 226 - GACTCTCGCATGCAATCTTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.9974435288388984 50.25293994326296 50.0 no 16201 chrII_45908r 38995 intron YBL092W_intron 266 - CAGCTCCGAGAATTGTATCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.29479688926584163 48.080485931461446 45.0 no 16202 chrII_45677r 38996 intron YBL092W_intron 35 - CTCTCATAACAATGCAGTCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.9350934775197668 44.64533350999785 40.0 no 16203 chrII_47117r 38997 intron YBL091C-A_intron 7 + TGACGAGAATTGCTAGTGTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.0705434070770502 43.34477981719322 45.0 no 16204 chrII_60322 38999 intron YBL087C_intron 356 - TCGATGGTTATCCATTAGTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.009836382119344192 45.15687049137006 35.0 no 16205 chrII_60372r 39002 intron YBL087C_intron 303 + TCTGGTTTCAAAATCATACA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.204814683533908 38.79152365256578 30.0 no 16206 chrII_60455r 39004 intron YBL087C_intron 220 + ACATAAATTCAGTTTTTAAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.8378689411398533 30.66614049906491 15.0 no 16207 chrII_60542 39007 intron YBL087C_intron 136 - ACACCGATAGGTATATGATC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.7271718601919356 43.236787000774605 40.0 no 16208 chrII_89232 39009 intron YBL072C_intron 189 - ATCTCTTCTTGTGAAAAACT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.25309163306359256 38.16430526212065 30.0 no 16209 chrII_89357r 39010 intron YBL072C_intron 61 + TCTTTGAATGGAATAGATAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.6257838631433305 34.673641134764125 30.0 no 16210 chrII_89361 39011 intron YBL072C_intron 60 - TATCTATTCCATTCAAAGAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.3516410507075239 38.18453528553653 30.0 no 16211 chrII_89369r 39012 intron YBL072C_intron 49 + CTACAGGACCTCTCTTTGAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.8184631994908381 47.8714452387544 45.0 no 16212 chrII_168496r 39017 intron YBL027W_intron 74 - CCTTATCTATTTCTCTCCAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.0897906477433013 47.65101104604537 35.0 no 16213 chrII_168718 39022 intron YBL027W_intron 293 + GCTCTTTACTGTTAGGTTTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.5465189950667689 48.98677358882282 40.0 no 16214 chrII_332893r 39023 intron YBR048W_intron 20 - TTTCATTGATTACCTCATTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.21276569443915985 42.78723284638125 30.0 no 16215 chrII_332905 39025 intron YBR048W_intron 29 + AATCAATGAAATATTCAGTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.16496621003319414 31.34949386467474 20.0 no 16216 chrII_333009r 39027 intron YBR048W_intron 136 - ACCAGTAAACTTTTACTTGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.339147343164073 40.15109040790117 30.0 no 16217 chrII_333043r 39028 intron YBR048W_intron 170 - AACGAAATCTCAATCATTCG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2094941861426323 36.86143291089644 35.0 no 16218 chrII_333279r 39031 intron YBR048W_intron 406 - AATCGTTAACTGTGTCGTGG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.9392813355964629 45.0464508454781 45.0 no 16219 chrII_333303r 39033 intron YBR048W_intron 430 - CCTACTATTTTTAGGCGAAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4874803758844564 42.21217157228824 35.0 no 16220 chrII_333311r 39034 intron YBR048W_intron 438 - ACTTCATTCCTACTATTTTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6094323537010969 43.08979548837277 25.0 no 16221 chrII_366500r 39035 intron YBR062C_intron 62 + TGCACTCATCATTAGATTAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.15682521338686112 41.65035206348256 35.0 no 16222 chrII_366531 39036 intron YBR062C_intron 34 - TTCGGTTAGTTAATTGGCTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.07727467915248401 45.5061248070075 35.0 no 16223 chrII_366532 39037 intron YBR062C_intron 33 - TCGGTTAGTTAATTGGCTTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.029564600819200614 45.50612480700744 35.0 no 16224 chrII_393226r 39038 intron YBR078W_intron 48 - CTCGAGATTTGTGAGGAAAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.08681159365480717 40.77850203375078 45.0 no 16225 chrII_393237 39039 intron YBR078W_intron 56 + ACAAATCTCGAGTAGATTCG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.13875589699896276 40.14552595687826 40.0 no 16226 chrII_393355r 39040 intron YBR078W_intron 177 - TCGAAACCCGTTTCCTCTTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5042339055651613 51.361313321519326 45.0 no 16227 chrII_393408 39043 intron YBR078W_intron 227 + TCAATATTTCTGCCTGTCAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.03206011005010168 46.952260085239686 35.0 no 16228 chrII_393414 39044 intron YBR078W_intron 233 + TTTCTGCCTGTCATAGGATT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.2312097674452251 50.37626257433163 40.0 no 16229 chrII_393415 39045 intron YBR078W_intron 234 + TTCTGCCTGTCATAGGATTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.13086523917608608 49.50133006234825 40.0 no 16230 chrII_414752r 39048 intron YBR084C-A_intron 485 + TAACTAACATGACTTTAACA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.8391402498567093 33.59697014451376 25.0 no 16231 chrII_414960 39051 intron YBR084C-A_intron 280 - TATCGCTATAAATATCTTAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3255209802368418 33.36147753630217 20.0 no 16232 chrII_415042 39053 intron YBR084C-A_intron 198 - ACTCCGATTATAGAAACATC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.19746065096646845 39.20851663944677 35.0 no 16233 chrII_415134 39055 intron YBR084C-A_intron 106 - TTCAATAACGCTGGTGTTTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.3642482086009069 44.27327157732929 40.0 no 16234 chrII_426588r 39060 intron YBR089C-A_intron 263 + TCTACTGTAGTATCCTCTAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7378143149880012 45.15373470654788 35.0 no 16235 chrII_426621r 39061 intron YBR089C-A_intron 230 + GCATGCTCAAGTTGTAAGTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6184439313579497 47.48981334101092 45.0 no 16236 chrII_426784r 39066 intron YBR089C-A_intron 67 + GCTAGAACAGGATACAGCTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.0072806956331275 45.51955806026467 45.0 no 16237 chrII_592599 39068 intron YBR181C_intron 150 - TGTCGGTACGTGTATATTAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.4596427033143856 43.68468417643777 40.0 no 16238 chrII_592732 39071 intron YBR181C_intron 17 - TCATTAGAATTCTAAGGATT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.14202562933818433 35.81921807878393 25.0 no 16239 chrII_592726 39072 intron YBR181C_intron 23 - GCTGATTCATTAGAATTCTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.177891374314867 40.27380138299816 30.0 no 16240 chrII_604700r 39074 intron YBR189W_intron 188 - CCCTGTTTAACTGAAGTGTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.40451090991649 47.75882555459975 45.0 no 16241 chrII_604753 39075 intron YBR189W_intron 238 + GAACATCTCTCTCGTAACAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.20201098660027567 42.054215059384774 40.0 no 16242 chrII_604754 39076 intron YBR189W_intron 239 + AACATCTCTCTCGTAACAAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.25993305499646985 40.88263107935927 35.0 no 16243 chrII_604859r 39078 intron YBR189W_intron 347 - CCCGGAACAAAAGTCTGCAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7197235501758321 46.01442707832496 50.0 no 16244 chrII_606303 39079 intron YBR191W_intron 22 + TCTACAGCACGAACGAATCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3911101558212645 43.40056042629681 45.0 no 16245 chrII_653388 39083 intron YBR215W_intron 19 + TCAATTATCCGCCCTTCGTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7521912500904757 53.52364527483303 45.0 no 16246 chrII_653400r 39084 intron YBR215W_intron 34 - ATCTAAAACACCCCTAACGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5048381875091605 43.46667369016279 40.0 no 16247 chrII_653399r 39085 intron YBR215W_intron 33 - TCTAAAACACCCCTAACGAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4446516062182944 42.222089896916316 40.0 no 16248 chrII_662655r 39090 intron YBR220C_intron 325 + TCTTCTGTGATTGGCAGAGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.052646243884124574 49.33137663061342 45.0 no 16249 chrII_662664r 39093 intron YBR220C_intron 316 + ACAGCCAGCTCTTCTGTGAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.22251153358191966 55.694544702674186 50.0 no 16250 chrII_662855 39100 intron YBR220C_intron 128 - TCTCATTAACAGATTTACAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.1239789823544275 37.59850100924888 30.0 no 16251 chrII_679993r 39102 intron YBR230C_intron 24 + TATCGCCTAATCTTTTCTCC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2433420680600211 49.32645189688589 40.0 no 16252 chrIV_65315r 39106 intron YDL219W_intron 11 - ACTAACGAAGCTGAAAAAAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3879290813841022 32.650483011454924 35.0 no 16253 chrIV_117730r 39107 intron YDL191W_intron 66 - TCGAGGCTCTTTCTTGCACT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.030443753639396862 54.67508302615072 50.0 no 16254 chrIV_117747r 39109 intron YDL191W_intron 83 - TCCAAAAGTTTAACGCTTCG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.8078796983986017 41.798407399053595 40.0 no 16255 chrIV_117948r 39110 intron YDL191W_intron 284 - GTCAAACGCTAGGCGATCTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.5626845425383673 48.20896070287819 50.0 no 16256 chrIV_117882 39112 intron YDL191W_intron 215 + GCATACATCTTTAAATTCAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.12858902567244626 37.77153429270175 30.0 no 16257 chrIV_216245r 39114 intron YDL137W_intron 90 - GAACTCATCCCACCGTTCAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.1870277355765409 53.68006724370383 55.00000000000001 no 16258 chrIV_216237 39115 intron YDL137W_intron 79 + GACTCTCTCCACTGAACGGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.304228181674616 52.94673173635766 55.00000000000001 no 16259 chrIV_216279r 39119 intron YDL137W_intron 124 - ACGGCTTCCTGATCAAATAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.5453732198171741 44.0961641770848 40.0 no 16260 chrIV_216278r 39120 intron YDL137W_intron 123 - CGGCTTCCTGATCAAATAAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.28252792697426266 42.35075013829356 40.0 no 16261 chrIV_216317 39121 intron YDL137W_intron 159 + GGGCCTAGTTATCCTAATTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.5605366837363024 49.93918199752801 45.0 no 16262 chrIV_216319 39122 intron YDL137W_intron 161 + GCCTAGTTATCCTAATTGTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7508599721845421 47.692905941403296 40.0 no 16263 chrIV_216329r 39123 intron YDL137W_intron 174 - CTGCTCGACTCCCCACAATT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.43628610387823297 55.63177902744792 55.00000000000001 no 16264 chrIV_217735r 39125 intron YDL136W_intron 135 - CTCTCTGATATTTGCCTGCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.0389754831594476 52.32914957374293 45.0 no 16265 chrIV_217764r 39126 intron YDL136W_intron 164 - TTCTGTTACCAAGTTGTAGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.8134482903114812 47.3109801311133 40.0 no 16266 chrIV_217780 39127 intron YDL136W_intron 177 + AACAGAAATTTATAAGTTTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9203210484223062 28.97344303152352 15.0 no 16267 chrIV_217800 39128 intron YDL136W_intron 197 + TGGCACTTGTTAAAATTGTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.1499859990353963 39.92235249400249 30.0 no 16268 chrIV_230088r 39129 intron YDL130W_intron 71 - TTCAAAATTGCGCATTTCTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.2094326446685173 41.75919911821506 35.0 no 16269 chrIV_230146 39130 intron YDL130W_intron 126 + CTCTAACATGATGAGATACT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.7455677076965328 38.944085647671045 35.0 no 16270 chrIV_230190 39132 intron YDL130W_intron 170 + TTCTCCATTAACGTATTTAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.036158386053564806 38.94676519677592 25.0 no 16271 chrIV_230271 39133 intron YDL130W_intron 251 + ACGAATAACGACTCTTCCTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.08549159193877537 42.98446049923575 40.0 no 16272 chrIV_230287r 39134 intron YDL130W_intron 270 - ATACATATAACAAGCTCCAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.2968502767977064 39.921729626295814 30.0 no 16273 chrIV_239464r 39135 intron YDL125C_intron 23 + GCTTACACTCACACCAATGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5553354190535046 47.67016175660422 45.0 no 16274 chrIV_307442 39136 intron YDL083C_intron 304 - GTACCCTGGCACTTCCTCTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.5822499742614242 61.19028245446458 55.00000000000001 no 16275 chrIV_307470 39138 intron YDL083C_intron 276 - TCTGTTCAAAATTCATTGCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5744353131948559 40.355416987355106 30.0 no 16276 chrIV_307658r 39140 intron YDL083C_intron 85 + TCACCTGAATAAGACGGGTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.5131432548418785 45.437838728361676 50.0 no 16277 chrIV_307663 39143 intron YDL083C_intron 83 - CCCGTCTTATTCAGGTGATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.7990646044355412 51.406670235068255 45.0 no 16278 chrIV_307664r 39145 intron YDL083C_intron 79 + ACCATATCACCTGAATAAGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.28369173863514 41.74717168000876 35.0 no 16279 chrIV_307725r 39146 intron YDL083C_intron 18 + ACGATGTCACGAATTTGTGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.05941834053356426 42.646492588970254 40.0 no 16280 chrIV_308481 39148 intron YDL082W_intron 53 + AAGCTCGCTTGTTACCTTAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.029033924250696837 49.3129425806622 45.0 no 16281 chrIV_308495r 39149 intron YDL082W_intron 70 - TGCACTAGTATAATCCTCTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.14837221703487213 44.751982386529455 35.0 no 16282 chrIV_308612 39150 intron YDL082W_intron 184 + TAACTGAGCAGTCATAGTAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.013405578331385 40.349567649319674 35.0 no 16283 chrIV_308632 39151 intron YDL082W_intron 204 + TGGCCAAGCAAATTCGAGAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2345832014130493 46.14177472677494 50.0 no 16284 chrIV_308635r 39153 intron YDL082W_intron 210 - GGTCCTGTCTCGAATTTGCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.4430803918467943 54.25551843213128 50.0 no 16285 chrIV_308656r 39154 intron YDL082W_intron 231 - TTCAGCAAATAGTGGTACAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9248082260528824 40.43124475959269 35.0 no 16286 chrIV_314050r 39155 intron YDL079C_intron 264 + ATCACATTATATACTAACAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5497970107282288 34.020394527792746 20.0 no 16287 chrIV_322310r 39157 intron YDL075W_intron 30 - CCATTCAGATGACAAGCCCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.7667707075469632 52.454636597174776 50.0 no 16288 chrIV_322394r 39159 intron YDL075W_intron 114 - GATCAATGATCTTTGTTGAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.2811718987424267 39.58604473785033 30.0 no 16289 chrIV_322454 39160 intron YDL075W_intron 171 + TCAATATTATAACATCCAAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7850927081995024 34.19948547336077 25.0 no 16290 chrIV_337582r 39163 intron YDL064W_intron 60 - TCGATTTGTTAGTATACCGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.17874948723821488 46.024928414687956 40.0 no 16291 chrIV_340914 39165 intron YDL061C_intron 286 - TTTCGACTATCGAAGTTAAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.3985944197310977 36.67837397558185 30.0 no 16292 chrIV_341027 39166 intron YDL061C_intron 173 - CACATCGTCTTATTCCACCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5052925450464714 51.39498946573264 45.0 no 16293 chrIV_341028 39167 intron YDL061C_intron 172 - ACATCGTCTTATTCCACCAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4343127266880238 50.153883787805064 40.0 no 16294 chrIV_341044r 39170 intron YDL061C_intron 153 + GAGCCTTTCTGGTGGCCCCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.5289730905248122 66.92546768557236 65.0 no 16295 chrIV_491617 39176 intron YDR025W_intron 57 + TTGCTGATATATATCGTCTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.537968879119181 41.9731082255006 35.0 no 16296 chrIV_491742 39178 intron YDR025W_intron 182 + GCGTTAATTAACTACAAAAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.0995291565297896 33.735035629867184 30.0 no 16297 chrIV_491761r 39180 intron YDR025W_intron 204 - TATCAAGCCTTCGGCACCGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.028912157057486287 56.89284907535034 60.0 no 16298 chrIV_491770r 39181 intron YDR025W_intron 213 - TGCTACCTTTATCAAGCCTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.08927680134061554 50.59508853089267 40.0 no 16299 chrIV_491811 39182 intron YDR025W_intron 251 + TTACGTTTACGATAGTTGAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.17158228059861955 39.58776101275771 30.0 no 16300 chrIV_491812 39183 intron YDR025W_intron 252 + TACGTTTACGATAGTTGATT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2475703202499685 39.58776101275771 30.0 no 16301 chrIV_579623r 39185 intron YDR064W_intron 147 - AACTATACCTGTGTACACAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -3.4765604657285807 43.4290432089266 40.0 yes 16302 chrIV_579663 39187 intron YDR064W_intron 184 + TCTACTCGCTGTACATTAGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.086537355857886 48.76894778016555 45.0 no 16303 chrIV_579631 39188 intron YDR064W_intron 152 + TACACAGGTATAGTTTATAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3495244775226758 38.11633323960103 30.0 no 16304 chrIV_579746 39190 intron YDR064W_intron 267 + TTTCTCAGTATAATTTACGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5118298735015684 40.01076667659896 30.0 no 16305 chrIV_579760 39191 intron YDR064W_intron 281 + TTACGCCGGAAAATTACTGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.34247082758400405 41.967138162165845 40.0 no 16306 chrIV_579820 39192 intron YDR064W_intron 341 + AACATAACACGTTAACCTAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.2460687458251499 37.8606584699229 30.0 no 16307 chrIV_579835r 39193 intron YDR064W_intron 359 - AATCTTGGTTCTCCTCCGAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.2889221397949997 52.64775924207049 45.0 no 16308 chrIV_579850r 39194 intron YDR064W_intron 374 - TCCGGGTGATTCTTCAATCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.0004959128954729469 50.743265819697285 45.0 no 16309 chrIV_579868r 39196 intron YDR064W_intron 392 - CCATTAAAGTATAACTATTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.2199170931828628 34.36523421407878 25.0 no 16310 chrIV_579996 39198 intron YDR064W_intron 517 + CACTAAATATTACTTTAAAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3961123560955564 29.324396159455205 20.0 no 16311 chrIV_629978 39200 intron YDR092W_intron 72 + ACACTGTTTCCTCTTGATAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.10096863381584784 45.1382365045439 35.0 no 16312 chrIV_630116 39202 intron YDR092W_intron 210 + TTCAACAGAACAAACTACTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.0576622232111908 34.70764809875027 30.0 no 16313 chrIV_630115 39203 intron YDR092W_intron 209 + ATTCAACAGAACAAACTACT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7609648602998704 35.22463380443543 30.0 no 16314 chrIV_653041r 39205 intron YDR099W_intron 263 - TTCAGAATGCAACATCACAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.11160954815858788 41.318615074116614 40.0 no 16315 chrIV_653042r 39206 intron YDR099W_intron 264 - TTTCAGAATGCAACATCACA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.0843016868454791 41.13837100949911 35.0 no 16316 chrIV_653115 39207 intron YDR099W_intron 334 + ACCAATCCGTAATTCAAGCG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2409455938396121 45.64519172251597 45.0 no 16317 chrIV_653116 39208 intron YDR099W_intron 335 + CCAATCCGTAATTCAAGCGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.11400953370912995 47.525443371647434 45.0 no 16318 chrIV_653116r 39209 intron YDR099W_intron 338 - CCCACGCTTGAATTACGGAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.26988910050138715 49.61795466103371 50.0 no 16319 chrIV_653150r 39210 intron YDR099W_intron 372 - ATTCGCTGTATTATTATCTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4963444505213079 42.199644053911136 30.0 no 16320 chrIV_653188r 39211 intron YDR099W_intron 410 - CCGTTCTTCCTAAACAAAAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.100167596389288 39.684467942975225 35.0 no 16321 chrIV_653436 39213 intron YDR099W_intron 655 + TCAAAAAAAATTGCCTCTCC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7004227478940432 38.90909972484798 35.0 no 16322 chrIV_715278 39216 intron YDR129C_intron 61 - AACGTTTATTACAACCTAAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3790902446907455 35.491616829410304 25.0 no 16323 chrIV_1073341 39218 intron YDR305C_intron 41 - CCATATAGTTAGTAACGCAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.27491183595567903 41.35735296279285 35.0 no 16324 chrIV_1237055 39221 intron YDR381W_intron 212 + ACTTCAAATCATGGCCTATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.34493212680295376 43.91104947146408 35.0 no 16325 chrIV_1237069r 39222 intron YDR381W_intron 229 - GCTGGTAATTCCAACCTTAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.962123574359688 48.11238727594247 40.0 no 16326 chrIV_1237161 39223 intron YDR381W_intron 318 + TCAATCTTACATTTTTAAGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.0464157104761518 36.8630233249288 25.0 no 16327 chrIV_1237235 39225 intron YDR381W_intron 392 + ATCATCCAATACTGAAGTTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5828387253277616 40.44409185380249 35.0 no 16328 chrIV_1237316 39226 intron YDR381W_intron 473 + CCATTTTCAAAAAATAGCTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.41639024438912936 35.30164595544181 25.0 no 16329 chrIV_1237459 39229 intron YDR381W_intron 616 + TCGTGGTACATGTTTATTTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.25418824267975576 43.032441130077814 35.0 no 16330 chrIV_1237526r 39230 intron YDR381W_intron 686 - GGACAATACACAAACAATCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.013425700814415076 36.430189810650354 35.0 no 16331 chrIV_1238657 39231 intron YDR381C-A_intron 148 - TCCTACTTTCGTCTTCACTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.1164437276811774 51.064806432718456 40.0 no 16332 chrIV_1238669 39233 intron YDR381C-A_intron 136 - CTTCACTTTGGTTATATATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.0891914937822228 39.089371285951984 25.0 no 16333 chrIV_1238692 39234 intron YDR381C-A_intron 113 - TGCAATCAAACTCTGCTTCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6635024531419391 44.99401267624 40.0 no 16334 chrIV_1238707 39235 intron YDR381C-A_intron 98 - CTTCAAGGGATAGGCCAATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.2636166883594073 46.70990733326147 45.0 no 16335 chrIV_1355379 39238 intron YDR447C_intron 152 - TCTTCTAAACTAATCAGTAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.8842034410304704 34.614201613858825 25.0 no 16336 chrIV_1355284r 39239 intron YDR447C_intron 244 + TATCCAATGGTCTTGAAGAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.138952043936917 42.2859875216829 40.0 no 16337 chrIV_1355297r 39240 intron YDR447C_intron 231 + GCACATTCTATCTTATCCAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3134000803742115 45.589579417016814 35.0 no 16338 chrIV_1355502 39244 intron YDR447C_intron 29 - AGCGCCCAGTCCATCATATC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.06391973662453143 58.220671511906964 55.00000000000001 no 16339 chrIV_1355521 39245 intron YDR447C_intron 10 - CCGGCTTCATCAACATCTCG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.5489177024643983 51.80563201189994 55.00000000000001 no 16340 chrIV_1360044 39247 intron YDR450W_intron 74 + TTCATTCACCTCTTTAATCG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.625162299158564 43.915552929175185 35.0 no 16341 chrIV_1360166 39249 intron YDR450W_intron 196 + ATCAAAAAGGAACATGAATT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5250718849614304 31.14287567696323 25.0 no 16342 chrIV_1360187 39251 intron YDR450W_intron 217 + GGCATAAGCGCACATAATTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.1910245266813501 43.853340152414496 40.0 no 16343 chrIV_1360210 39253 intron YDR450W_intron 240 + AACATTGCAATAGCGGTCGG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.041096702900479 46.8835568027215 50.0 no 16344 chrIV_1360252 39255 intron YDR450W_intron 282 + TACAATGAATCAGCTATTGG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.0321556933217408 38.69158841156048 35.0 no 16345 chrIV_1360305 39256 intron YDR450W_intron 335 + TCCTGCTCCGATTTTTGTCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.4387518119240989 55.169238147751166 45.0 no 16346 chrIV_1401853 39261 intron YDR471W_intron 52 + GACTTTCAGGTGCATAAGAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.28840301167382193 44.64962767291649 40.0 no 16347 chrIV_1450506 39267 intron YDR500C_intron 321 - AACTAAATAAACTCTACTGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.09693483811448077 34.09377945591598 30.0 no 16348 chrIV_1450643 39269 intron YDR500C_intron 184 - GTGCAATTTCTTATCATCAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6156247245081906 41.21291933178753 30.0 no 16349 chrIV_1450717 39270 intron YDR500C_intron 110 - AACGTAGGTCTTAGTTTACC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.39996707702222656 45.73179070282794 40.0 no 16350 chrIV_1450745r 39271 intron YDR500C_intron 79 + CACTGAAAAAATTTTCCACC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2796908411480593 38.488986520629346 35.0 no 16351 chrIV_1450785r 39272 intron YDR500C_intron 39 + TCACATCCGGTCTGATTTAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3805473257035533 48.34680843338254 45.0 no 16352 chrIV_1450529 39273 intron YDR500C_intron 298 - ATTCAGAACAACTTCATTGG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3165737073126689 39.33512217942013 35.0 no 16353 chrIV_1450798r 39274 intron YDR500C_intron 26 + AGTCAACGTTCAATCACATC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6842750259665361 42.84471114061 40.0 no 16354 chrV_158994r 39275 intron YER003C_intron 71 + TAACGCGTACGACTCTATGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.9781906549517684 45.52660143903097 45.0 no 16355 chrV_270070r 39280 intron YER056C-A_intron 56 + CAACTAAAAAAGAGCAAGAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7902249205518097 31.173000153382983 35.0 no 16356 chrV_306360r 39281 intron YER074W_intron 37 - GCAACTTTAACATGGAATAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.8678133962841 37.179513415702566 30.0 no 16357 chrV_306382r 39282 intron YER074W_intron 59 - TTGCCTTTTATACTAACTCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.2489610365156667 43.22573378982725 30.0 no 16358 chrV_306475 39285 intron YER074W_intron 149 + ACTATTGGCTAATATATTAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.17143530322407974 34.36347768243064 20.0 no 16359 chrV_362746r 39288 intron YER102W_intron 16 - CTTCTACTTTCTCATTTGCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.6351161192461812 47.66591921040782 35.0 no 16360 chrV_362747r 39289 intron YER102W_intron 17 - CCTTCTACTTTCTCATTTGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4784631878430869 49.772240353686364 40.0 no 16361 chrV_362930 39291 intron YER102W_intron 197 + ACCGAAGAATTATCGATGCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9266015036815092 42.51723846090261 40.0 no 16362 chrV_362931r 39292 intron YER102W_intron 201 - TCCTTGCATCGATAATTCTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.3304240102434575 45.729599155291616 35.0 no 16363 chrV_362945 39293 intron YER102W_intron 212 + ATGCAAGGAAAAATGGGTCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.4175757214084097 40.66551925984521 40.0 no 16364 chrV_397006r 39295 intron YER117W_intron 198 - TCGCTATCTGGATGTAGGCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.0925309175117357 52.3952495057186 50.0 no 16365 chrV_397043r 39296 intron YER117W_intron 235 - GGCATCCATTTAACGCTTTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.2560409755028002 48.1277792289805 40.0 no 16366 chrV_397069r 39297 intron YER117W_intron 261 - TAACCTTCTCAGTAATCAGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.04643544146637012 43.985137560586224 35.0 no 16367 chrV_397171r 39298 intron YER117W_intron 363 - ATCAACACAAATATATTTCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.08511242745718686 33.25974042189972 20.0 no 16368 chrV_397066 39299 intron YER117W_intron 255 + TTTCCAACTGATTACTGAGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.09399022141730523 42.30945594707174 35.0 no 16369 chrV_423778r 39300 intron YER131W_intron 190 - TCTTTTGTGGATTATAGTGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.15015887155169005 43.036034138467016 30.0 no 16370 chrV_423781 39301 intron YER131W_intron 190 + ACACTATAATCCACAAAAGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.30562055313594194 36.11295009299266 30.0 no 16371 chrV_423782 39302 intron YER131W_intron 191 + CACTATAATCCACAAAAGAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.493257355328428 35.738697456117904 30.0 no 16372 chrV_432743r 39303 intron YER133W_intron 74 - AACTATCTTACTGCCGCAAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.07024756298010365 46.662917246647396 45.0 no 16373 chrV_432818r 39304 intron YER133W_intron 149 - GGCTATCTCGACATATGAGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -2.102558319841293 47.842115905389726 45.0 yes 16374 chrV_432839r 39305 intron YER133W_intron 170 - GCTAAACACACACATTATCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -2.453132109809992 40.780872141470006 35.0 yes 16375 chrV_433027r 39308 intron YER133W_intron 358 - TTTCGTCCGACCTTTCTCTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -6.719124113692538 55.12775848718825 50.0 yes 16376 chrV_433051r 39309 intron YER133W_intron 382 - TTCTGCAAATCCACATTTCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4396167982654567 45.407215920232886 35.0 no 16377 chrV_548606 39310 intron YER179W_intron 53 + TCTTTTACTAACTAATAATT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.2848459634881797 31.261300375402694 15.0 no 16378 chrVI_54375r 39311 intron YFL039C_intron 288 + TTGCTATATTATATGTTTAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.5314141916677382 35.09445688669274 20.0 no 16379 chrVI_54635r 39314 intron YFL039C_intron 29 + TAACTGTAAGAAGAATTGCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.17921228572061212 35.138928552255265 30.0 no 16380 chrVI_64720 39316 intron YFL034C-A_intron 181 - TTGCCTCTGTTAAAGCTATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7649664810917657 45.20875423842017 35.0 no 16381 chrVI_64802 39318 intron YFL034C-A_intron 99 - CCACTAGTTCGCTGTGAAAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2415655583285367 47.28176652396457 50.0 no 16382 chrVI_64803 39319 intron YFL034C-A_intron 98 - CACTAGTTCGCTGTGAAAGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5524059888509641 47.168762741858025 50.0 no 16383 chrVI_221370r 39322 intron YFR031C-A_intron 22 + CAACCATGTGATTGTCGTAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9702032972789952 43.81569141827015 40.0 no 16384 chrVI_223532 39326 intron YFR032C-A_intron 220 - AGCTAACTGCCAATCTGAAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.20410308850780806 44.76411255311052 45.0 no 16385 chrVI_223543 39328 intron YFR032C-A_intron 209 - AATCTGAAGTGGTGCTAGCG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.8452941054903875 47.5279565048649 50.0 no 16386 chrVI_223544 39329 intron YFR032C-A_intron 208 - ATCTGAAGTGGTGCTAGCGG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.22490226001336505 51.61096508625529 55.00000000000001 no 16387 chrVI_223618 39332 intron YFR032C-A_intron 134 - TTCGCTATAAGTTCAAACAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.1923969847524238 39.088310645750205 35.0 no 16388 chrVI_223697 39335 intron YFR032C-A_intron 55 - CACTCAGCGCACCTCAGATT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.54434907424405 54.8532535303882 55.00000000000001 no 16389 chrVI_223717 39336 intron YFR032C-A_intron 35 - TGGCTACCTGCATTTCCAAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7355079904631024 52.490572758424946 45.0 no 16390 chrVII_31478r 39338 intron YGL251C_intron 78 + CTCTTTCTTTTATTATCTAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5380128100113525 38.91582706418268 25.0 no 16391 chrVII_148867r 39341 intron YGL189C_intron 77 + GACAAGATATTATTAAAACA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.15349540153369218 29.431816250041837 20.0 no 16392 chrVII_150293 39345 intron YGL187C_intron 213 - TCGAATTCTTCATTATATGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.39151492347785216 37.205376068788546 25.0 no 16393 chrVII_150302 39346 intron YGL187C_intron 204 - TCATTATATGATGGACAATT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9329321799515268 36.15133921212709 25.0 no 16394 chrVII_150350r 39348 intron YGL187C_intron 153 + TCGTTCCCTGCTTTTCTATT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6272944310288107 53.71560544490859 40.0 no 16395 chrVII_157199r 39349 intron YGL183C_intron 61 + GCTACCCTCTTCTTATTATT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2916492836712137 49.829556341811035 35.0 no 16396 chrVII_157198r 39350 intron YGL183C_intron 62 + CTACCCTCTTCTTATTATTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.09596887374035992 45.450712798644076 30.0 no 16397 chrVII_157228r 39351 intron YGL183C_intron 32 + ACTGAACACTAACTTATAGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.32105939247610393 36.10405223115612 30.0 no 16398 chrVII_167376 39353 intron YGL178W_intron 21 + CCAATATTTTTCTTCGCCAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2807846728519123 45.80653493918976 35.0 no 16399 chrVII_167441 39354 intron YGL178W_intron 86 + TAACCAAAAACCAGCTTCAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2066862565287832 40.89415218893134 40.0 no 16400 chrVII_167783r 39358 intron YGL178W_intron 431 - ACTTCAATGGCGACAGAGGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.11926807367150813 47.60905369752339 50.0 no 16401 chrVII_167796r 39359 intron YGL178W_intron 444 - TCTATAAAGTTCGACTTCAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.32209385980508165 37.65288211390015 30.0 no 16402 chrVII_167828 39360 intron YGL178W_intron 473 + TCTTGATTCTCACGCATCTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.058547063982300473 49.53455870159821 45.0 no 16403 chrVII_167854r 39362 intron YGL178W_intron 502 - CACAACCATGTACAGTGTCC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7026295176963228 50.029748320489034 50.0 no 16404 chrVII_167934 39364 intron YGL178W_intron 579 + CTGCACACGCCTTATTTTTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9635818779393176 49.29999113303876 45.0 no 16405 chrVII_249910r 39366 intron YGL137W_intron 26 - GAGCTTGTTCGCAATTGCAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.012296520568758018 49.8576297497316 45.0 no 16406 chrVII_311181r 39368 intron YGL103W_intron 168 - AAGCCGTCTCAACAGTGAGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.541475115657038 49.35873838718669 50.0 no 16407 chrVII_311237r 39369 intron YGL103W_intron 224 - TCTTTTTGCTCAGTTTGCGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5797665039874652 50.31541920955613 40.0 no 16408 chrVII_311328 39370 intron YGL103W_intron 312 + ACTCATTTTACGGCTATAAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.4670440560020112 39.67352763236863 30.0 no 16409 chrVII_365054 39371 intron YGL076C_intron 359 - TACACGGCATTATCACTCAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.357362524528061 44.514246192885025 40.0 no 16410 chrVII_365069 39372 intron YGL076C_intron 344 - CTCAATGGTTTTTCTGACAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.14329949574618978 43.969595085273056 40.0 no 16411 chrVII_365111 39373 intron YGL076C_intron 302 - ACCTTAATACCTTAACTCTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5077262335129517 43.34418685043931 35.0 no 16412 chrVII_365299r 39375 intron YGL076C_intron 111 + TGCAATATTCTCAACACCTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.5360705915009113 43.83759341988025 40.0 no 16413 chrVII_438054 39377 intron YGL031C_intron 324 - TCAGGCGTTCGCAAAATTGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.6079247651645077 46.87668127420511 45.0 no 16414 chrVII_438060 39378 intron YGL031C_intron 318 - GTTCGCAAAATTGTAGGAAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.3751888276054141 39.370455050533856 40.0 no 16415 chrVII_438180r 39379 intron YGL031C_intron 195 + TTCATTACATATATACGATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.03896643524753994 34.216486611412336 20.0 no 16416 chrVII_438209 39380 intron YGL031C_intron 169 - TCATTGGGTTTCCTGCTCAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4409577400072481 52.78338567873482 45.0 no 16417 chrVII_438235 39381 intron YGL031C_intron 143 - ACATATATTATAAGTTATAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4583429459669995 29.528426144383847 15.0 no 16418 chrVII_438271r 39383 intron YGL031C_intron 104 + ACCGGAATTTAGACTTTGAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4484006211211058 42.61713179258237 40.0 no 16419 chrVII_438289r 39384 intron YGL031C_intron 86 + GCTTCAGATAGCCAATACAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3591774227522432 46.97321340098989 45.0 no 16420 chrVII_438336 39385 intron YGL031C_intron 42 - TTCTAGCACAACGCTGCCCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.4246677246854245 56.6880932165368 55.00000000000001 no 16421 chrVII_439231r 39389 intron YGL030W_intron 140 - TCACTTTTATTTCACAGTCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2948509393053125 43.385975548508846 30.0 no 16422 chrVII_534610 39390 intron YGR027C_intron 156 - TCCTTCTCTCAAAGTACCAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.1579600319975061 48.681501867726816 40.0 no 16423 chrVII_534516 39391 intron YGR027C_intron 250 - ACCGAACTCTAGTAGAATTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.1706653986006184 41.37098523175007 35.0 no 16424 chrVII_534677 39392 intron YGR027C_intron 89 - TCATCCCATTAAGGTAGAAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.10614070819838596 44.3166638711553 40.0 no 16425 chrVII_534741 39393 intron YGR027C_intron 25 - TCATCTTATCCGCCTAATAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.3075271649265762 46.68063498036946 35.0 no 16426 chrVII_534626r 39394 intron YGR027C_intron 137 + AGCACAGATCTAGCTACCCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.29231759275254 54.11603923754915 50.0 no 16427 chrVII_556018 39396 intron YGR034W_intron 187 + AGCTTTTGCATATTCAATCC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.267396488415409 45.82117117667673 35.0 no 16428 chrVII_556100r 39397 intron YGR034W_intron 272 - TCAATATTGGATTCTAAAGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.17371752156932124 36.65491213124301 30.0 no 16429 chrVII_556024 39398 intron YGR034W_intron 193 + TGCATATTCAATCCAGGCAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.462522710383313 48.178338915247146 40.0 no 16430 chrVII_556025 39399 intron YGR034W_intron 194 + GCATATTCAATCCAGGCATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.07245038706356327 47.6534898881194 40.0 no 16431 chrVII_556188 39400 intron YGR034W_intron 357 + ATGCATACTCCGTTGGATGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.15333724883341773 50.83213012521577 45.0 no 16432 chrVII_727079r 39403 intron YGR118W_intron 43 - ACCTAAAACGATATCACAAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.33796929214106536 36.314381232603814 30.0 no 16433 chrVII_727078r 39404 intron YGR118W_intron 42 - CCTAAAACGATATCACAATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5434637696806275 35.47058594896964 30.0 no 16434 chrVII_727234 39407 intron YGR118W_intron 196 + ATTCTTCCCAATCTATAGTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.20308629530003336 45.294003207175074 35.0 no 16435 chrVII_787811 39408 intron YGR148C_intron 348 - CACAAGGTGAAATACACTCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6786546247541556 39.940964749521974 40.0 no 16436 chrVII_788066r 39411 intron YGR148C_intron 90 + ACAATGCTGAGGTTAATAAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6822852993352351 37.53238795509958 35.0 no 16437 chrVII_859382 39415 intron YGR183C_intron 72 - TTTCCAAAGCCCATGATACT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.7250188159406498 48.20380461195117 40.0 no 16438 chrVII_859391r 39417 intron YGR183C_intron 60 + CTTCCTTAGCCAAGTATCAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.0545650108349571 49.42116025477117 40.0 no 16439 chrVII_859392r 39418 intron YGR183C_intron 59 + TCTTCCTTAGCCAAGTATCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2522465427998757 50.55698082477551 40.0 no 16440 chrVII_920682r 39419 intron YGR214W_intron 20 - ACATTACTCTATTATATAAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.13403315155589288 32.27172712695977 15.0 no 16441 chrVII_920751 39422 intron YGR214W_intron 86 + CCGCCAACCAAACGGAATGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.5028082124601351 50.236233139081214 60.0 no 16442 chrVII_920758r 39423 intron YGR214W_intron 96 - TGCTATCCCAGCATTCCGTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.04457754028088013 57.99329358081008 50.0 no 16443 chrVII_921098 39426 intron YGR214W_intron 433 + TTCTTCTTTAATTTTGTTTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2507996893742864 38.07683994198789 20.0 no 16444 chrVIII_107840r 39433 intron YHR001W-A_intron 11 - TCTAGCTCACATAATATGAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2983762622120545 39.54676680017315 30.0 no 16445 chrVIII_126590r 39435 intron YHR010W_intron 41 - TTTCTAATACCACAGTTGCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.7384874729887945 45.09177690841546 35.0 no 16446 chrVIII_126614r 39436 intron YHR010W_intron 65 - AACATCAACTGCTAATAACT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.4944714066878995 36.7090867093213 30.0 no 16447 chrVIII_126656 39437 intron YHR010W_intron 104 + TCGAGTATTGTATCTTCATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.0011990598879406155 41.52640754983385 30.0 no 16448 chrVIII_126879r 39444 intron YHR010W_intron 330 - ACTTTCACCATCTTATTTGG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.9935392828226868 45.349121677227174 35.0 no 16449 chrVIII_126930 39446 intron YHR010W_intron 378 + CACATGTACGCAGGCGACCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -3.3096778503238777 54.25194590275731 60.0 yes 16450 chrVIII_126976r 39448 intron YHR010W_intron 427 - CACGAATTTTTAATAGGGCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.25199168675151584 40.44381693618328 35.0 no 16451 chrVIII_126978 39449 intron YHR010W_intron 426 + ATGCCCTATTAAAAATTCGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6430426735449841 40.88835382596028 30.0 no 16452 chrVIII_129547 39451 intron YHR012W_intron 18 + TCTTCTCTGGTTAGCTGTAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3308648299609529 50.908090900903865 45.0 no 16453 chrVIII_129626 39453 intron YHR012W_intron 97 + TAACGACTTCAATTGCAAGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.7576134708098377 39.93400332505717 35.0 no 16454 chrVIII_138300 39454 intron YHR016C_intron 89 - AACTCATGCCCCATAAGCAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9423771013806492 49.6580856598489 45.0 no 16455 chrVIII_138309r 39456 intron YHR016C_intron 77 + AGTCTGTGTCCATTGCTTAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.7355336392844065 51.88458827006127 40.0 no 16456 chrVIII_138357 39457 intron YHR016C_intron 32 - TGCATCCATAAGTTTAGAGG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.1926587561051389 44.52713741287198 40.0 no 16457 chrVIII_138354 39458 intron YHR016C_intron 35 - AGCTGCATCCATAAGTTTAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.02891495519330412 46.44924635428696 40.0 no 16458 chrVIII_138359 39459 intron YHR016C_intron 30 - CATCCATAAGTTTAGAGGAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.3077643599210159 42.09719492075516 40.0 no 16459 chrVIII_148344r 39465 intron YHR021C_intron 300 + AGCATATGGTGTTGAGTTAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.9188135816592248 44.902687743219296 35.0 no 16460 chrVIII_148358r 39466 intron YHR021C_intron 286 + CTACTGTGGAGATAAGCATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7368171773963256 42.5106755332199 40.0 no 16461 chrVIII_148345r 39467 intron YHR021C_intron 299 + AAGCATATGGTGTTGAGTTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.02739050719707462 43.292116561477606 35.0 no 16462 chrVIII_148467r 39468 intron YHR021C_intron 177 + CAACAAATCATGCATTAAAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.8221206456990574 33.49323925006388 30.0 no 16463 chrVIII_148505 39470 intron YHR021C_intron 142 - ATACTCCTATCAAATGTCAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.2872292652577209 41.14407908573321 35.0 no 16464 chrVIII_251227 39475 intron YHR076W_intron 71 + ACTAACTTTTCTCATATCAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.490012044583469 39.118473815802865 25.0 no 16465 chrVIII_298445 39477 intron YHR097C_intron 20 - TTACACTGTAGTGCAATTTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9788126276807204 41.63174468737628 30.0 no 16466 chrVIII_354888r 39478 intron YHR123W_intron 26 - TTCTGACTTCTGCACTTTAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4526284654849885 44.494052185040566 35.0 no 16467 chrVIII_354878r 39479 intron YHR123W_intron 16 - TGCACTTTAAAGGCAGCCAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6932236753324788 47.94473790275015 45.0 no 16468 chrVIII_382471r 39480 intron YHR141C_intron 254 + TCTGGTTAGAAAATATATTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.087872389635792 32.817417175195544 25.0 no 16469 chrVIII_382524 39481 intron YHR141C_intron 204 - ATTCAGGTGTTCAGTACTTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7599357524832261 46.92664676948772 35.0 no 16470 chrVIII_382698r 39482 intron YHR141C_intron 27 + CCATGTTATTTATCTCCATT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3880254562188287 45.783236775242244 30.0 no 16471 chrVIII_505422 39483 intron YHR203C_intron 75 - TCACTTGTACCAATCATGAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.1089867822306734 43.651498738617924 40.0 no 16472 chrIX_68723r 39486 intron YIL148W_intron 10 - AACTATGTTTAGAATGGATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.02377852419519844 34.85186141165445 25.0 no 16473 chrIX_68747 39487 intron YIL148W_intron 31 + TTCGAACGTTCAGAGCTTAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.8558532591241048 43.20060857711627 40.0 no 16474 chrIX_68866 39489 intron YIL148W_intron 150 + AAACTGCCAAACTGAATATG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.0112051422400479 36.73084068965164 35.0 no 16475 chrIX_68895r 39490 intron YIL148W_intron 182 - TCACTAAGTCATTCCTAGAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.5699453110641458 44.26440481391915 40.0 no 16476 chrIX_68985r 39491 intron YIL148W_intron 272 - CACAAATTTGGATATTTCTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.5709832142398481 36.660867783291394 25.0 no 16477 chrIX_69020r 39492 intron YIL148W_intron 307 - GCTCTCATCGTCATATCTTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.27659869134057913 49.65827783792185 45.0 no 16478 chrIX_69021r 39493 intron YIL148W_intron 308 - AGCTCTCATCGTCATATCTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.03726002617431007 49.799003779626105 40.0 no 16479 chrIX_69022r 39494 intron YIL148W_intron 309 - GAGCTCTCATCGTCATATCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.7369337527685084 50.814427912844174 45.0 no 16480 chrIX_99095r 39495 intron YIL133C_intron 268 + ATCAATAATAATCTTCAACC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.8482937855598028 34.66674667022386 25.0 no 16481 chrIX_99250 39496 intron YIL133C_intron 116 - TTCTGTATTCCACCCTTCTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2918917862739057 53.917623742464066 45.0 no 16482 chrIX_127795 39505 intron YIL123W_intron 133 + TCGTGCTCAACCGCTATTTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.4856639990303199 51.11062460361165 45.0 no 16483 chrIX_127845 39507 intron YIL123W_intron 183 + GACATTCGTCACGAAAATTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3083772605004558 38.730367812444854 40.0 no 16484 chrIX_127848 39508 intron YIL123W_intron 186 + ATTCGTCACGAAAATTGCGG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.17703393066586756 42.64598822612811 45.0 no 16485 chrIX_127969r 39511 intron YIL123W_intron 310 - AAGCATTAATGGCTATTTTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7056725877972965 39.97446136136159 30.0 no 16486 chrIX_128022 39513 intron YIL123W_intron 360 + ATCTTAAATAAGATGTAGAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9035006961687732 31.734750325789605 25.0 no 16487 chrIX_155269r 39514 intron YIL111W_intron 49 - ACACCTCGAATGTTAGTAAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.01423731945884596 40.48617969776444 35.0 no 16488 chrIX_166474 39516 intron YIL106W_intron 39 + TCATCTTTTATTAACAAACT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2006857606741224 34.07160905536665 20.0 no 16489 chrIX_225852 39517 intron YIL073C_intron 28 - CGTCCAGATAAAAGTTAATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.272057523947273 36.220699538525366 30.0 no 16490 chrIX_232095r 39518 intron YIL069C_intron 249 + TCAGCGAGAACAAATTCCCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2622658571409967 46.2079213668307 45.0 no 16491 chrIX_232111 39520 intron YIL069C_intron 236 - TCGCTGATCTTACGTTACTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5173637108709582 46.769352982756565 45.0 no 16492 chrIX_232285 39521 intron YIL069C_intron 62 - GCCACCCATAATGCTATAAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.5856199791370863 48.34026285438637 45.0 no 16493 chrIX_232304r 39522 intron YIL069C_intron 40 + ACTGCAAGTAAGCTCTATTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.03036210167169759 44.457657872415105 40.0 no 16494 chrIX_256612r 39523 intron YIL052C_intron 392 + CACTCAAGTTCTTAAATCAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.1508928803698516 38.2103501855259 30.0 no 16495 chrIX_256640 39524 intron YIL052C_intron 367 - GCTCCATATGAAAAGTATTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.606312160565031 39.64344144530526 30.0 no 16496 chrIX_256684 39525 intron YIL052C_intron 323 - TCATTTCAATCTTTCAACAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.21375258936383884 38.649332139888884 30.0 no 16497 chrIX_256643r 39526 intron YIL052C_intron 361 + ACGCCGAAATACTTTTCATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.04353626360209117 42.294278663576385 35.0 no 16498 chrIX_256934r 39527 intron YIL052C_intron 70 + ACTTTCATTGTGGGAAAATG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7706299312518626 38.758300966584564 35.0 no 16499 chrIX_316820r 39528 intron YIL018W_intron 51 - TCAAAACATCTAAGTCATAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.4529588746460333 34.12797840641633 30.0 no 16500 chrIX_316925 39530 intron YIL018W_intron 153 + CTTCGAAACGATTACTATCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.10602812323188246 38.831600557625215 35.0 no 16501 chrIX_317084r 39531 intron YIL018W_intron 315 - TCAAAATATGGCAAAGTAAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.9388632982813699 31.495893178838912 25.0 no 16502 chrIX_348406 39532 intron YIL004C_intron 69 - GTCAATAACTCCCAATATCG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.5949739749937244 42.9693804694751 40.0 no 16503 chrIX_348417r 39533 intron YIL004C_intron 55 + CTACCATAACACCTCGATAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.02898527842367785 44.73409052848177 40.0 no 16504 chrX_74019 39537 intron YJL191W_intron 222 + TCAATGCTATTGTGTTATAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.19223897918222088 39.193196192471866 30.0 no 16505 chrX_75963r 39540 intron YJL189W_intron 27 - GATCAGTTCAGCATCTAACT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.6089426046175128 45.97347433038624 40.0 no 16506 chrX_76017 39541 intron YJL189W_intron 78 + TGACCTTACCACCTACAATT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4222671860660211 47.674492836439974 40.0 no 16507 chrX_76020r 39542 intron YJL189W_intron 84 - AATCCAAATTGTAGGTGGTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.14733880474734462 42.391485617629534 35.0 no 16508 chrX_76025r 39543 intron YJL189W_intron 89 - TTTCAAATCCAAATTGTAGG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.2699606756826731 37.230439797465294 30.0 no 16509 chrX_76113r 39544 intron YJL189W_intron 177 - GCGACTTTAGATTTCTGTTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.10273783533209056 45.205144800777646 35.0 no 16510 chrX_76135 39545 intron YJL189W_intron 196 + CCACTACGCAGATTAAAATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.1409258119749657 39.24905930167301 35.0 no 16511 chrX_76135r 39546 intron YJL189W_intron 199 - CCATATTTTAATCTGCGTAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.2656547015525042 42.305205995009096 35.0 no 16512 chrX_76165 39547 intron YJL189W_intron 226 + CTGCTTATTCTGAGAACTTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6675786775231507 42.97605808645432 35.0 no 16513 chrX_76192r 39551 intron YJL189W_intron 256 - CCACCTGACATAAACCACGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.9111955910090102 49.9795813459242 55.00000000000001 no 16514 chrX_91306r 39553 intron YJL177W_intron 214 - CACTATGCTATACGCTTAAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6738172429849612 42.05444236182802 35.0 no 16515 chrX_156902r 39554 intron YJL136C_intron 325 + CATCATAATTCCGAATTAGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.006294515799420364 39.33565382221599 30.0 no 16516 chrX_156925 39555 intron YJL136C_intron 305 - TCTTTTCAGCATATCTCTCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.0722577626570759 48.4014564785449 35.0 no 16517 chrX_156972r 39556 intron YJL136C_intron 255 + GTACACATCTCTAAGAAATG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -2.174934240358077 36.62773283611364 35.0 yes 16518 chrX_157000r 39559 intron YJL136C_intron 227 + ACCTGATACTTTATCATGTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.03358539441896255 42.99413414574377 35.0 no 16519 chrX_157082r 39561 intron YJL136C_intron 145 + ACATGGGTTTATAATCATAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -2.0378152677348496 37.892502037642096 25.0 yes 16520 chrX_172477r 39567 intron YJL130C_intron 253 + TCTGATTTTATATCGGCATC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.1563827574882056 43.429945111228896 35.0 no 16521 chrX_172530r 39568 intron YJL130C_intron 200 + GCAATTGATAGAGATCTTCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.02386690313423068 41.38109410494149 35.0 no 16522 chrX_172612 39569 intron YJL130C_intron 121 - GACATCATCGCAGAGTCAAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.6777363669997795 44.76621668050228 45.0 no 16523 chrX_435251r 39575 intron YJL001W_intron 26 - ACTTTTAGAAACAATAAAGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.8412344978263573 30.29192455050787 20.0 no 16524 chrX_435295 39576 intron YJL001W_intron 67 + TGGCCTTATTACTAACTAAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.012256655476816314 40.879676713613655 30.0 no 16525 chrX_435298r 39577 intron YJL001W_intron 73 - ATACCTATTAGTTAGTAATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.33117435405373097 35.91217354330809 20.0 no 16526 chrX_608411r 39578 intron YJR094W-A_intron 107 - TCCTCAACTGCGATATTTCG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.20809544475487746 47.017015969587185 45.0 no 16527 chrXI_93331 39580 intron YKL186C_intron 115 - TTGCCTGACGATCAGCCTGG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.0008346044943912 56.46553053044681 60.0 no 16528 chrXI_109606r 39582 intron YKL180W_intron 31 - CAACTCATTCTTGTTTCATC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.2278433631686323 43.13084360872893 35.0 no 16529 chrXI_109818 39583 intron YKL180W_intron 240 + ATCTTTTTCAATTACTTAAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.8116418653840087 34.37191081540038 20.0 no 16530 chrXI_109753r 39584 intron YKL180W_intron 178 - ACAAAATCATAAACACGTAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.2252059321549236 31.29020007116918 25.0 no 16531 chrXI_155331r 39585 intron YKL157W_intron 62 - CTCATGTTCAAAATAATCAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.32015364405508284 34.55409668666749 30.0 no 16532 chrXI_155363r 39587 intron YKL157W_intron 94 - ACAAGGCTAGTAATACATCC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.11654246671752586 43.38685392290506 40.0 no 16533 chrXI_155436r 39588 intron YKL157W_intron 167 - CTGCAGAAGATAAGAATATG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.26785045715115674 34.682800132189016 35.0 no 16534 chrXI_155447 39589 intron YKL157W_intron 175 + TATCTTCTGCAGCAGGAAAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.32610062427646985 43.63658729846696 40.0 no 16535 chrXI_155477r 39590 intron YKL157W_intron 208 - TTCTATCAAAGTCAATTAGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.15402359447449207 36.380538719266845 25.0 no 16536 chrXI_155476r 39591 intron YKL157W_intron 207 - TCTATCAAAGTCAATTAGTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9328360492659152 36.380538719266845 25.0 no 16537 chrXI_158628r 39593 intron YKL156W_intron 15 - TCCAGTTGCGCTGCATTTAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.764720154317583 53.5268292018701 45.0 no 16538 chrXI_166463r 39599 intron YKL150W_intron 66 - GCTTCAAAACGTTAGTATTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.007470512049694955 39.08672406270756 35.0 no 16539 chrXI_283212 39600 intron YKL081W_intron 116 + ACAGTTATCCCTGTCTGAAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.6924852101530365 48.85702988456433 40.0 no 16540 chrXI_283248r 39604 intron YKL081W_intron 155 - TACAAATATCAACATATGAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.2695010445261441 31.059854244233804 25.0 no 16541 chrXI_283402 39606 intron YKL081W_intron 306 + TCGAGATGATGTATATTTAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.8298224009183719 36.46557073092247 30.0 no 16542 chrXI_430531 39607 intron YKL006C-A_intron 46 - TAACATCCATATAGCAAGCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -3.9339063725976477 43.018048464788244 35.0 yes 16543 chrXI_430555r 39608 intron YKL006C-A_intron 19 + CACGCATAGGTGTTTAGAAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3059185011568025 43.84440054219641 40.0 no 16544 chrXI_430500r 39609 intron YKL006C-A_intron 74 + TAACTATTGCTTCTGTACAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -5.190504475868097 41.740639464865296 35.0 yes 16545 chrXI_432215r 39613 intron YKL006W_intron 183 - CACTATAGGCCACTCCAACA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.2460638459646949 51.31924185098217 50.0 no 16546 chrXI_432260 39614 intron YKL006W_intron 225 + CAGCTTACCTAGTTTCAGAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.08591093568191621 46.5541043605391 40.0 no 16547 chrXI_449980 39617 intron YKR005C_intron 21 - TCTAGAGAATATTAGTACCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9483289628400632 39.61428527480058 30.0 no 16548 chrXI_551824 39618 intron YKR057W_intron 143 + CCGATAATAAGCAACTCCGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4019322558798962 44.415064351044684 45.0 no 16549 chrXI_551767 39619 intron YKR057W_intron 86 + TCATAATGCAAACAAAACGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4213328786164807 34.46231222041166 30.0 no 16550 chrXI_551824r 39624 intron YKR057W_intron 146 - CCTTCGGAGTTGCTTATTAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3351558689602063 48.72946378644304 40.0 no 16551 chrXI_618654 39625 intron YKR094C_intron 69 - CCATTTATGTCTTTCGTTTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.13341363058901778 44.900314683800275 30.0 no 16552 chrXI_618697r 39626 intron YKR094C_intron 23 + ACTATGTTCGAAATAATATG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.3890338153283665 32.44333931936052 25.0 no 16553 chrXII_40288r 39628 intron YLL050C_intron 90 + TCTTTCCTCCCTTTTTAACA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2492953214089645 50.41691584121833 35.0 no 16554 chrXII_242387 39629 intron YLR048W_intron 65 + CCCGATTTAATCATATTTGG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7302872262809467 42.60820023093271 35.0 no 16555 chrXII_286492r 39634 intron YLR078C_intron 42 + AACAAGATGTAATACTAACA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3812451776560733 32.064644116599595 25.0 no 16556 chrXII_286493r 39635 intron YLR078C_intron 41 + AAACAAGATGTAATACTAAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7722297937049989 29.660584029722262 25.0 no 16557 chrXII_327310 39636 intron YLR093C_intron 70 - AACATAGTAAAATTATGGCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.09329136376517318 34.20193149465541 25.0 no 16558 chrXII_398578 39637 intron YLR128W_intron 45 + ACTAACACTTTATTGGCAAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.38175703413517403 39.716615864505464 35.0 no 16559 chrXII_522770r 39639 intron YLR185W_intron 103 - AGTCTTGCTAAGTATAAATT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.4031998296015108 36.805026262763135 25.0 no 16560 chrXII_522867r 39641 intron YLR185W_intron 200 - AGCAGAATATTTCTTCTATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7298485296224491 38.44717388879343 25.0 no 16561 chrXII_522992r 39642 intron YLR185W_intron 325 - AATCAAATTGTTGTGCAATT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.0906697037919173 36.59837090041872 25.0 no 16562 chrXII_712911r 39644 intron YLR287C-A_intron 222 + GCTTGACACAGATTTTTCGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5683141942741864 45.41207301179953 40.0 no 16563 chrXII_713059r 39646 intron YLR287C-A_intron 74 + AGCTAATTTGAATATATTAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.28574718465459825 32.16722291800636 20.0 no 16564 chrXII_744213 39648 intron YLR306W_intron 59 + ACTAACATAATCTTTTTGGG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.03636764709900702 37.881427498583946 30.0 no 16565 chrXII_744251 39649 intron YLR306W_intron 97 + GTACTGGATATGTATATTCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.6242736978932971 40.724732976268115 30.0 no 16566 chrXII_796042 39650 intron YLR333C_intron 274 - CTGCAGACTAAACTGTATGG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7178534947069785 42.60625656445024 45.0 no 16567 chrXII_796261r 39652 intron YLR333C_intron 52 + CCAAAATCAAAGCCAAATCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7446121952679464 38.73288816712386 35.0 no 16568 chrXII_796262r 39653 intron YLR333C_intron 51 + GCCAAAATCAAAGCCAAATC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.7962744166207754 40.242649648219704 40.0 no 16569 chrXII_819394r 39654 intron YLR344W_intron 66 - TCATTCTGCCCTCAGGCAAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.1900635078406756 54.210817223848494 50.0 no 16570 chrXII_819351 39655 intron YLR344W_intron 20 + TCACTGAAACCCTGTAGAGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5123765887153109 48.76359977594467 50.0 no 16571 chrXII_819492 39656 intron YLR344W_intron 161 + TGTCTCATAACTGCAACCAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3008155073744461 46.48446843948727 45.0 no 16572 chrXII_819593 39657 intron YLR344W_intron 262 + TCTAGCCGTATCTTACCTTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.1596967961827647 50.658407833630406 40.0 no 16573 chrXII_819651r 39658 intron YLR344W_intron 323 - GCATAATATAGTGTAATTTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9810631712547976 35.28472083606624 25.0 no 16574 chrXII_819713r 39660 intron YLR344W_intron 385 - ATCTTACCCTCTTAGTAAGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.31977192659375464 48.59855792294292 40.0 no 16575 chrXII_856739 39664 intron YLR367W_intron 164 + GGCAGTATACTAATTTATAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.13099639271619867 37.94923084497663 30.0 no 16576 chrXII_898238r 39667 intron YLR388W_intron 83 - TTTCAGCATTACTTTCGACG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.17661778543441006 44.663250838441456 40.0 no 16577 chrXII_898174 39668 intron YLR388W_intron 16 + ATTCGAATTTAAAGGTTATG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5543394668424513 33.67183878053322 25.0 no 16578 chrXII_898527 39673 intron YLR388W_intron 369 + TATCGCATGGACGGAATAAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.540014081035785 41.88446859290229 45.0 no 16579 chrXII_931417 39676 intron YLR406C_intron 262 - AAGCATCACGCCAAAAACAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.27090112389732146 41.66234165199433 40.0 no 16580 chrXII_931605 39678 intron YLR406C_intron 74 - TCACCCGTATAGATTTCGCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.7906220072204129 51.49303128759146 45.0 no 16581 chrXII_1028944r 39682 intron YLR448W_intron 78 - CCCTTCCTGCTTTTGTTCTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.13517214340074327 58.210207298465214 45.0 no 16582 chrXII_1029107r 39683 intron YLR448W_intron 241 - CTCAAAAAAATTCTTAGCGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.34192848688424393 35.51331452885256 30.0 no 16583 chrXII_1029231 39686 intron YLR448W_intron 362 + CATCACGATATGTCAATTAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.1707946369712286 38.37549540996594 30.0 no 16584 chrXII_1029164r 39687 intron YLR448W_intron 298 - TGCACAATTGATGGTGGGCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2991864948447096 50.45040582282643 50.0 no 16585 chrXIII_23391r 39688 intron YML124C_intron 245 + CTTCTTCTTCGGAGGATTGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.07503480012252417 51.12112786133747 50.0 no 16586 chrXIII_23430r 39689 intron YML124C_intron 206 + TCATAATTGACCTCATTACA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4651726513156105 40.85218594074848 30.0 no 16587 chrXIII_23546r 39693 intron YML124C_intron 90 + ATTCCCAATTGGTCACCATC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.0035035332688276 51.87122377190377 45.0 no 16588 chrXIII_23590 39695 intron YML124C_intron 49 - AACTTCTTTCCCTGTCCCAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.14689673536478434 56.923206423867505 50.0 no 16589 chrXIII_123867 39701 intron YML073C_intron 271 - AAACTAAATAATCATGAGCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6457909337235535 32.91130566492728 25.0 no 16590 chrXIII_123868 39702 intron YML073C_intron 270 - AACTAAATAATCATGAGCTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2943120042997866 33.53608758197646 25.0 no 16591 chrXIII_124128r 39706 intron YML073C_intron 7 + CCTACATGTTAATTTCGAGG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.6173607028523178 43.24530531649356 40.0 no 16592 chrXIII_124129r 39707 intron YML073C_intron 6 + TCCTACATGTTAATTTCGAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.6621967956422574 41.833642607021496 35.0 no 16593 chrXIII_124131r 39708 intron YML073C_intron 4 + GTTCCTACATGTTAATTTCG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.03811592555822197 43.297827462422454 35.0 no 16594 chrXIII_163482 39709 intron YML056C_intron 215 - CGTCAATTAATCACACATAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3695774625770559 36.3884090203689 30.0 no 16595 chrXIII_163629 39710 intron YML056C_intron 68 - TCACACCTTGGAAAACTTTA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.06009860628728825 41.16970152240839 35.0 no 16596 chrXIII_163510r 39711 intron YML056C_intron 184 + AATCATATTCGCACCTTTTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5657773153433524 44.045367921396064 30.0 no 16597 chrXIII_163483 39712 intron YML056C_intron 214 - GTCAATTAATCACACATAAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7057459618515112 34.84427151551421 25.0 no 16598 chrXIII_211481r 39713 intron YML034W_intron 39 - AACTGTTATCATATAATAAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.501422753487354 30.73356765868135 20.0 no 16599 chrXIII_223464 39714 intron YML026C_intron 298 - TTCAACATGGCGCATCATTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3656372636351759 46.97605410361285 40.0 no 16600 chrXIII_225990 39718 intron YML024W_intron 98 + GACGATATTTTCAGACGATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.2374499895642053 39.69747872662634 35.0 no 16601 chrXIII_226023r 39719 intron YML024W_intron 134 - TTTCAATCACACCACTTTTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2251176747370075 43.49756061793874 30.0 no 16602 chrXIII_226120r 39722 intron YML024W_intron 231 - TCCACAAGAGACTGAATCTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.978227002182768 43.88211535850331 45.0 no 16603 chrXIII_226146 39723 intron YML024W_intron 254 + TCTTTTTGCATAGTTGAACA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.297956189091522 41.67684536791643 30.0 no 16604 chrXIII_226191r 39724 intron YML024W_intron 302 - AAACACATTATAATGTGTAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.14282408113622794 32.376654600032914 25.0 no 16605 chrXIII_226268 39725 intron YML024W_intron 376 + TTGCTTTTCGTCATTTTAAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.8749533808702122 41.43372815600151 25.0 no 16606 chrXIII_236615 39726 intron YML017W_intron 23 + TAACCCCTTTTGATCCATAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.007448615479169419 46.78272393187393 35.0 no 16607 chrXIII_236692 39727 intron YML017W_intron 100 + CTTCTGTTTCAGTCATACGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.029867319369796225 48.25255631165408 40.0 no 16608 chrXIII_236782r 39728 intron YML017W_intron 193 - GAGCATTGTTCAATTGTTAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4954644577409721 41.66560813687386 35.0 no 16609 chrXIII_236932 39730 intron YML017W_intron 340 + GTCTACATATGTTTCTATTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7604987765895685 41.40180218562284 30.0 no 16610 chrXIII_337818 39731 intron YMR033W_intron 0 + GTACGTATTTAGTTCATCAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.25090928334732665 40.57250005511661 30.0 no 16611 chrXIII_499988 39732 intron YMR116C_intron 144 - TCAGAGATCTTGGTGATAAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.33041347142956845 41.021679138698175 35.0 no 16612 chrXIII_499878r 39733 intron YMR116C_intron 251 + AACAAAAATGATATAATGAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.26064595324155915 26.50922445461339 20.0 no 16613 chrXIII_499978 39734 intron YMR116C_intron 154 - AAACCATTCATCAGAGATCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4861012784861219 42.00336570912083 35.0 no 16614 chrXIII_517761 39738 intron YMR125W_intron 197 + TTACTTTGTTTTACATTCCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7905142664987144 43.06873588994704 25.0 no 16615 chrXIII_517862r 39739 intron YMR125W_intron 301 - TAACGGTAAAATCATATGCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3190496792040325 36.25338787472191 30.0 no 16616 chrXIII_537543 39741 intron YMR133W_intron 94 + CACTACAAATATGAATGAAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.03610888667788745 30.31478526293347 25.0 no 16617 chrXIII_550863 39742 intron YMR142C_intron 321 - TTTCTGATAAACGAATCTCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.09463748505512712 37.09663388175478 30.0 no 16618 chrXIII_550982r 39744 intron YMR142C_intron 199 + ACTTTGACCAGTTTATAAAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.17093640963257695 37.962582517297285 25.0 no 16619 chrXIII_551062 39746 intron YMR142C_intron 122 - AGCGGGATCTAATTATTCCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.5957547199714923 46.93122750668374 40.0 no 16620 chrXIII_551087r 39747 intron YMR142C_intron 94 + TAACACTGTAAATTAACAGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.8797861021212829 33.2659444143693 25.0 no 16621 chrXIII_552030 39749 intron YMR143W_intron 78 + CAGCCAACCAAGTTCTGAGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.15625324595945206 51.34519734289735 50.0 no 16622 chrXIII_552066 39751 intron YMR143W_intron 114 + CGCATAGTGTATTTATCCAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.04198124345571752 44.004862333928536 35.0 no 16623 chrXIII_552120 39752 intron YMR143W_intron 168 + GATCCAATTAGGCAATGTTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.12826950126796166 43.7036810493513 35.0 no 16624 chrXIII_552192 39753 intron YMR143W_intron 240 + CCAGTACGATTGTACACATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2468108624097076 44.4897201443556 40.0 no 16625 chrXIII_651227r 39758 intron YMR194W_intron 69 - CTCATGTTCTTCTCGTATTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3492418902324607 46.855330020029896 35.0 no 16626 chrXIII_651226r 39759 intron YMR194W_intron 68 - TCATGTTCTTCTCGTATTTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5830839519162931 44.88450180843307 35.0 no 16627 chrXIII_651338 39760 intron YMR194W_intron 177 + ACCATTTAATATGCATACAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.3579695372110249 39.54716051117497 30.0 no 16628 chrXIII_651602 39766 intron YMR194W_intron 441 + CAACCTGTGTCCTTATATTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.05568569025323383 46.477278663613454 35.0 no 16629 chrXIII_666933r 39768 intron YMR201C_intron 62 + AACGATGAGATGAGCTGTGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -2.1859493653156963 45.93051419995107 50.0 yes 16630 chrXIII_721259r 39769 intron YMR225C_intron 64 + TGGCTAAACTAGGCTGAGGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5378254503005624 49.376337133118 50.0 no 16631 chrXIII_732507r 39772 intron YMR230W_intron 44 - ATCATCTTTGCTATCCATTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.0973042994353662 46.4853911970506 30.0 no 16632 chrXIII_732744 39774 intron YMR230W_intron 278 + ATCATTTACTTTACAGTTTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.024451955299082808 39.14704258968902 25.0 no 16633 chrXIII_732763r 39775 intron YMR230W_intron 300 - TTGCAATAATACGGAAACTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.01666445012938808 36.69420314408399 35.0 no 16634 chrXIII_753801r 39778 intron YMR242C_intron 396 + CCCTTTTCTCATGTGTCACA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4560901245676704 54.138306328967246 45.0 no 16635 chrXIII_753890 39779 intron YMR242C_intron 310 - GATCCATGAAAGTTTAACTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.3763144709227395 39.1433871012494 35.0 no 16636 chrXIII_753893r 39780 intron YMR242C_intron 304 + ACACCTGAGTTAAACTTTCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5002714636005554 42.667126236235326 35.0 no 16637 chrXIII_753948 39781 intron YMR242C_intron 252 - TCTTTTGCAATCGTATTTCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.22779658231678995 43.728568290337925 30.0 no 16638 chrXIII_753952 39782 intron YMR242C_intron 248 - TTGCAATCGTATTTCTAGGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3715856463410631 43.5335557061868 35.0 no 16639 chrXIII_754071 39785 intron YMR242C_intron 129 - TCCTAGTTGAACTATTTTAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.8095273832053047 39.701865551023616 30.0 no 16640 chrXIII_754072r 39786 intron YMR242C_intron 125 + ACCACTAAAATAGTTCAACT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.4219838438223624 37.787131102778226 30.0 no 16641 chrXIV_62568 39794 intron YNL302C_intron 336 - TCCTTCCAACTTAAACGTCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.7388054701877191 46.552593224914744 40.0 no 16642 chrXIV_62574 39796 intron YNL302C_intron 330 - CAACTTAAACGTCTTGGTTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4178798728019122 41.47532207343285 40.0 no 16643 chrXIV_62788 39797 intron YNL302C_intron 116 - ACTTCAATTTATCAGGTAAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.4279717770680689 37.59058190548592 25.0 no 16644 chrXIV_62787 39800 intron YNL302C_intron 117 - AACTTCAATTTATCAGGTAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3751181110300768 36.25987194026658 25.0 no 16645 chrXIV_64115r 39801 intron YNL301C_intron 313 + CTCTTTTTGGCTTCAATTAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.05409385308158823 41.94815617824611 30.0 no 16646 chrXIV_64208r 39802 intron YNL301C_intron 220 + TACAATACGACCTTCAAGTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.4809835356112238 41.2064690940046 40.0 no 16647 chrXIV_64262 39804 intron YNL301C_intron 169 - ACTACCGCTTTCTGTTCTAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4732907054054122 50.54987684225989 45.0 no 16648 chrXIV_64407r 39806 intron YNL301C_intron 21 + CCAATTTTCTTCAGGATAAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.33374974107414623 39.32385135584929 30.0 no 16649 chrXIV_64415r 39807 intron YNL301C_intron 13 + TCTCCCTCCCAATTTTCTTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.01539361372610207 55.93821698847751 45.0 no 16650 chrXIV_185560 39809 intron YNL246W_intron 68 + CACTTAGCAAGTGCGGTAGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.6767316145129999 49.15288428482268 50.0 no 16651 chrXIV_331368r 39812 intron YNL162W_intron 45 - TCAAATTAGCTTTTCTTTAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4540776098288014 37.115848690944965 20.0 no 16652 chrXIV_331530r 39814 intron YNL162W_intron 207 - TACTCTGTTGCTGCATATCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.0533724460996745 49.5366022338224 40.0 no 16653 chrXIV_331345r 39816 intron YNL162W_intron 22 - TCCTGATTTTATTCACCATT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4450380054368099 45.719083042140426 30.0 no 16654 chrXIV_415024r 39820 intron YNL112W_intron 115 - GTCTCTCTTCTGTACTATCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.18233273559144889 49.92699333477043 40.0 no 16655 chrXIV_415199 39821 intron YNL112W_intron 287 + TCACTACAGAAAACTAATAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6825454467262817 32.2966459739647 25.0 no 16656 chrXIV_415200 39822 intron YNL112W_intron 288 + CACTACAGAAAACTAATATT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5097429835675599 31.81962281802765 25.0 no 16657 chrXIV_415571r 39827 intron YNL112W_intron 662 - CTTCTTAATAATTCGAACTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6568521755516692 35.47790574884084 25.0 no 16658 chrXIV_415572r 39828 intron YNL112W_intron 663 - ACTTCTTAATAATTCGAACT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.39513523871123707 35.649110580209936 25.0 no 16659 chrXIV_415681 39829 intron YNL112W_intron 769 + GCTTTCATTCAGTTTGAATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.35916743025098075 42.17904723794624 30.0 no 16660 chrXIV_415688 39830 intron YNL112W_intron 776 + TTCAGTTTGAATAAGGATTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7126442767577288 37.19887135035043 30.0 no 16661 chrXIV_415756 39832 intron YNL112W_intron 844 + TTCTGATAATCTTCAAGCCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.0920943634178007 44.12089594309265 35.0 no 16662 chrXIV_415757 39833 intron YNL112W_intron 845 + TCTGATAATCTTCAAGCCAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7799606139027666 43.92026043430446 40.0 no 16663 chrXIV_443913r 39836 intron YNL096C_intron 236 + GCGAAAAAGACCTTACCCCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.4428757649183324 48.8140747691096 50.0 no 16664 chrXIV_443953 39837 intron YNL096C_intron 199 - ATCGATATTGGTACTGACCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.008209952118308828 45.75157414106685 40.0 no 16665 chrXIV_444008 39838 intron YNL096C_intron 144 - TTCATGGTATTGACAGCTCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.025205333969122057 47.91497427172862 40.0 no 16666 chrXIV_444117r 39839 intron YNL096C_intron 32 + AACATTGTGATTTCTTCTAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.29764627187157844 37.684754868058796 25.0 no 16667 chrXIV_494626 39840 intron YNL069C_intron 328 - CCATTACTTTTTGGTGTGAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3643973547787753 46.0645803557581 35.0 no 16668 chrXIV_494625 39841 intron YNL069C_intron 329 - ACCATTACTTTTTGGTGTGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.157349581427764 46.53903602996911 35.0 no 16669 chrXIV_494648 39843 intron YNL069C_intron 306 - GGCATATCGATGCATCTCAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -2.5822312504418905 49.62676976426042 50.0 yes 16670 chrXIV_494699 39847 intron YNL069C_intron 255 - CACTTTTTAGGCGTGATGCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.0689497550978495 49.3136591451871 45.0 no 16671 chrXIV_494748 39848 intron YNL069C_intron 206 - AACGCATTCAATTAAGTATT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.16077540622608547 36.38432128933289 25.0 no 16672 chrXIV_494886 39849 intron YNL069C_intron 68 - TCAATTACTATATTCTGAAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.2467391913597743 32.54482015487389 20.0 no 16673 chrXIV_721770r 39856 intron YNR053C_intron 509 + TCAATTCTAACTTTACAAGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.827910472165768 36.101380107927696 25.0 no 16674 chrXIV_721883r 39857 intron YNR053C_intron 397 + CTCTTCGAAACAATCAATCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7486421186226677 38.75557994458728 35.0 no 16675 chrXIV_722019r 39858 intron YNR053C_intron 261 + CTTCGCTTTTTAGAACAGCG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.12657701333112947 45.87599525399026 45.0 no 16676 chrXIV_722091r 39862 intron YNR053C_intron 189 + TATCCATATTTCCCCGTTCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.1300037622766959 53.821526518415574 40.0 no 16677 chrXIV_722240 39864 intron YNR053C_intron 43 - AATCTCTCGTGCTATCCTCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -2.0138662694632483 52.7333352714751 45.0 yes 16678 chrXV_80449r 39866 intron YOL127W_intron 91 - TCGGATAGTTTATTTACGTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.20431900356438126 41.2277510146223 35.0 no 16679 chrXV_80696 39867 intron YOL127W_intron 335 + TGCTCCACGTCGAGGTATCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.2536768180624836 55.149623683738184 55.00000000000001 no 16680 chrXV_92519 39869 intron YOL121C_intron 292 - TACGTTTCATGAGAACTTAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6385020256427074 38.70634500932505 30.0 no 16681 chrXV_94067r 39874 intron YOL120C_intron 201 + TCAATTTATTGAACTGAATC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.06972295326772374 33.289769528706806 25.0 no 16682 chrXV_94090r 39875 intron YOL120C_intron 178 + CTTCTGATGTGACAAATTAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2952112760863265 37.59037339806565 30.0 no 16683 chrXV_94236r 39876 intron YOL120C_intron 32 + CAACGCCAATTATGGTTAGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.43816444460297815 43.6502210080439 40.0 no 16684 chrXV_242441r 39877 intron YOL047C_intron 41 + GTCATACTAACCGCCTTTGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.8362067647748783 49.984719657071246 45.0 no 16685 chrXV_242443 39878 intron YOL047C_intron 42 - TTCAAAGGCGGTTAGTATGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.24711237622079604 43.94879289375695 40.0 no 16686 chrXV_242440r 39879 intron YOL047C_intron 42 + TCATACTAACCGCCTTTGAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5517244296359426 46.057379590704784 40.0 no 16687 chrXV_506049 39880 intron YOR096W_intron 111 + GACTAGGACTCAAATGTATT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.14672574227055035 39.555835339243394 35.0 no 16688 chrXV_506132r 39882 intron YOR096W_intron 197 - GTTCCCTTCTTCTTAAACAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.2367929335491278 47.5305157116909 40.0 no 16689 chrXV_506186 39884 intron YOR096W_intron 248 + TTCTGATAGTTAATTACAAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6452189623607079 33.64750067257677 20.0 no 16690 chrXV_506231r 39885 intron YOR096W_intron 296 - ACTTGTAAATGATATATGCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.3309368737594163 35.990109353373214 25.0 no 16691 chrXV_552773 39887 intron YOR122C_intron 82 - TACGCGCATCAACAAAAATC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9876184114219768 38.657535903455646 40.0 no 16692 chrXV_552772 39888 intron YOR122C_intron 83 - TTACGCGCATCAACAAAAAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.3790845132312457 38.131008611190346 35.0 no 16693 chrXV_778962 39889 intron YOR234C_intron 405 - TCATTGAGCCCATGATGGAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.4395403023838694 48.779144392069504 45.0 no 16694 chrXV_779024 39891 intron YOR234C_intron 343 - ATACGCTATCTTAACATTTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.33686712318070033 39.565948510338565 30.0 no 16695 chrXV_779075 39893 intron YOR234C_intron 292 - TCCTGGTGCCTCCTACTACT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.8964925620187969 60.58374222226536 55.00000000000001 no 16696 chrXV_778971r 39894 intron YOR234C_intron 393 + AACTGCGTCCCTTTCCATCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3138916236515446 56.338876731236105 50.0 no 16697 chrXV_779188r 39895 intron YOR234C_intron 176 + ACAGAATGAACAAGTTTCAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4124427718048818 36.34849371920211 30.0 no 16698 chrXV_779260 39896 intron YOR234C_intron 107 - TAACAGTTGTCCAACAAGTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5721550839044636 41.762153159811135 40.0 no 16699 chrXV_779331 39897 intron YOR234C_intron 36 - GCTCGAATCAGCCTATTCCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7522535508311768 53.86220373565948 50.0 no 16700 chrXV_867169 39898 intron YOR293W_intron 19 + TCAGAAAGCATGAAGATACA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.02183167370069284 37.26981490859748 35.0 no 16701 chrXV_867371 39900 intron YOR293W_intron 221 + CAGCACAAGGCCATCGACCC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.097395128812165 57.47345634249177 65.0 no 16702 chrXV_867389r 39902 intron YOR293W_intron 242 - ACCATATTTCATACGTCTCC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.0267133051224275 48.3526459934468 40.0 no 16703 chrXV_867418r 39903 intron YOR293W_intron 271 - CCGTTTTCTTGCCCAAATAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.5009830450425398 49.271318889243624 40.0 no 16704 chrXV_900895 39906 intron YOR312C_intron 279 - TTTCCTCTATAATTCCTGGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4294052709739988 47.09292206961454 35.0 no 16705 chrXV_900909r 39908 intron YOR312C_intron 262 + GGACTATAGAACTACCATCC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.05961548584205392 45.849062196021244 45.0 no 16706 chrXV_900960 39909 intron YOR312C_intron 214 - ACCATATCATCAGTATTAAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.060077182101817776 37.684071549781606 25.0 no 16707 chrXV_900961r 39910 intron YOR312C_intron 210 + ACCATTTAATACTGATGATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.07240627626975149 37.15965741978442 25.0 no 16708 chrXV_901026 39911 intron YOR312C_intron 148 - TTCAGTATTCGGCGTATTTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.6423428915606436 47.13237597471277 40.0 no 16709 chrXV_901133r 39914 intron YOR312C_intron 38 + GTCAATGTAGCTATTTTATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.2713523626515596 38.81367166386003 25.0 no 16710 chrXVI_76072 39915 intron YPL249C-A_intron 132 - TCCACGGAGTACTGCAACGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.18800645549762104 53.130076195654965 60.0 no 16711 chrXVI_76142r 39917 intron YPL249C-A_intron 59 + CCAACAACAGAAATACAAAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.43872738789027976 33.66958109678825 35.0 no 16712 chrXVI_76106 39918 intron YPL249C-A_intron 98 - AAACGATGTTTGCATATCTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.594763558198704 40.41945623552755 35.0 no 16713 chrXVI_76192 39919 intron YPL249C-A_intron 12 - GCTCTACAGTTCATTAGTTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6437821695879713 47.792572826160786 40.0 no 16714 chrXVI_138733 39921 intron YPL218W_intron 7 + ATCACCCTGTTCACGTTTTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.3757446677925645 51.82232681171939 40.0 no 16715 chrXVI_173664r 39922 intron YPL198W_intron 1 - AAACATGGTAAATGAACATA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.6957046515987431 31.72769337223741 25.0 no 16716 chrXVI_173771r 39923 intron YPL198W_intron 108 - TTCGCGACTAACAAATGCCA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4555611443768675 45.378631254267304 45.0 no 16717 chrXVI_173754 39924 intron YPL198W_intron 88 + TTCTCGGTTTTACATTTCCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.22826280922720701 48.71876503108433 35.0 no 16718 chrXVI_173934r 39926 intron YPL198W_intron 271 - AACTCAATCTTGCAGATTCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.0646984098187732 43.06758766233003 35.0 no 16719 chrXVI_173980 39927 intron YPL198W_intron 314 + GTGCATATTTTTCACTAAAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.43075587596174936 38.171605075747955 25.0 no 16720 chrXVI_174051 39928 intron YPL198W_intron 385 + TTCTTGATGAATATTATTTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.1898321366932061 33.29240806491106 15.0 no 16721 chrXVI_281396r 39929 intron SNR17B_intron 85 + TCTTCTATTTCACCAGCTTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.21643772354635168 50.19365745827885 40.0 no 16722 chrXVI_281436 39930 intron SNR17B_intron 48 - AATCGCATTGCCTAATTATT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.1419201606701811 42.48260181906738 30.0 no 16723 chrXVI_282244 39931 intron YPL143W_intron 103 + AAGCTACCAGATCATATACG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5913339678622931 42.518464606295424 40.0 no 16724 chrXVI_282326r 39932 intron YPL143W_intron 188 - ACTTGGACCCTTTAGCTGTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.5896529954654048 54.71907641321746 50.0 no 16725 chrXVI_282471r 39933 intron YPL143W_intron 333 - ACAGTCAAATTGGATATCGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -1.3999922909136104 39.74803823896997 35.0 no 16726 chrXVI_378272 39937 intron YPL090C_intron 98 - TCTAAAATCTTTACGACGTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.9692372304024092 38.19927829082627 35.0 no 16727 chrXVI_405016 39939 intron YPL081W_intron 59 + TTGCTATGATTTTGAGGATC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.08803686604827847 42.12903336099913 35.0 no 16728 chrXVI_405010 39940 intron YPL081W_intron 53 + TCATACTTGCTATGATTTTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7485258081252246 40.26783541612508 30.0 no 16729 chrXVI_405155r 39941 intron YPL081W_intron 201 - GAACGCTTTACCTGAAGTGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.9520559537387796 46.83206803356836 45.0 no 16730 chrXVI_405083 39942 intron YPL081W_intron 126 + TCGTTTTGTTCAATAATGGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.3445563540084389 39.902412425494674 30.0 no 16731 chrXVI_405177r 39943 intron YPL081W_intron 223 - CTTCTAATGTTGAATTACTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6902552422665117 36.71738894357253 25.0 no 16732 chrXVI_405211r 39944 intron YPL081W_intron 257 - CAACAGACATAATCAGAACT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.8362428373811356 36.555712017644225 35.0 no 16733 chrXVI_405154r 39945 intron YPL081W_intron 200 - AACGCTTTACCTGAAGTGTC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2688726691115705 46.6548223924625 45.0 no 16734 chrXVI_405210r 39946 intron YPL081W_intron 256 - AACAGACATAATCAGAACTG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.17032177196844067 35.28106713482299 35.0 no 16735 chrXVI_405320 39948 intron YPL081W_intron 363 + TGCACAATTCTTTTGAAGAT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.367751453521001 39.32312640957889 30.0 no 16736 chrXVI_405395r 39949 intron YPL081W_intron 441 - CTCTTTTTCAAACGAATGCG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4956248721636382 40.80500873143637 40.0 no 16737 chrXVI_406715 39950 intron YPL079W_intron 68 + CCAATAAACATGTATGCAAG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6343238812386153 37.2777517297526 35.0 no 16738 chrXVI_406908 39951 intron YPL079W_intron 261 + AACAGCAATGATATGTTAGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.5599267892541278 39.59072604908943 35.0 no 16739 chrXVI_412277 39952 intron YPL075W_intron 15 + GCATTCTGAAAATGTTATCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7746732171339871 38.98366312762045 30.0 no 16740 chrXVI_412442r 39955 intron YPL075W_intron 183 - GCAAATTATATTGCATAAGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.1261118800687109 37.48318409894893 30.0 no 16741 chrXVI_412659r 39956 intron YPL075W_intron 400 - CTCTATTAATAATCCATAGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.6002220097280384 37.58383615490021 25.0 no 16742 chrXVI_412912 39958 intron YPL075W_intron 650 + CCATCAACTTCCTATAATAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.05774574048133596 39.984168072074 30.0 no 16743 chrXVI_412912r 39959 intron YPL075W_intron 653 - CCATTATTATAGGAAGTTGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.05278700157213 39.45711873287519 30.0 no 16744 chrXVI_623635r 39961 intron YPR028W_intron 60 - ACTGCTTCGGTTACGTGTGT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.14370918987101314 53.56354143169954 50.0 no 16745 chrXVI_623648r 39962 intron YPR028W_intron 73 - TCTTGTTAGTATAACTGCTT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.4629865996235905 42.31559035924039 30.0 no 16746 chrXVI_654186 39963 intron YPR043W_intron 18 + ACGATTTACCGTTTGCTTGG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.495952792878777 48.53462901327077 45.0 no 16747 chrXVI_654183 39964 intron YPR043W_intron 15 + CACACGATTTACCGTTTGCT invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.7681653424575277 48.87181789576943 45.0 no 16748 chrXVI_654194r 39965 intron YPR043W_intron 29 - ACACTACTCCTCCAAGCAAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 -0.07770182015563011 47.99220019069735 45.0 no 16749 chrXVI_654251 39966 intron YPR043W_intron 83 + CACAGACTTTTACGATATAA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.8116119586291854 36.76927494347285 30.0 no 16750 chrXVI_654365 39969 intron YPR043W_intron 197 + ACTTTCATTCATATACCTGA invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.16622014359618548 43.036761111893505 30.0 no 16751 chrXVI_833718 39974 intron YPR153W_intron 24 + TATCCGCCACGGCTGGATGC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.2757774925762927 59.14983509753148 65.0 no 16752 chrXVI_833721r 39976 intron YPR153W_intron 30 - ATGCCTGCATCCAGCCGTGG invalid seq invalid seq invalid seq invalid seq 0 0 0 0 1.4988695972703487 62.569414144283655 65.0 no 16753 chrXVI_911331 39977 intron YPR187W_intron 54 + AACTTCTATCATTGTGATAC invalid seq invalid seq invalid seq invalid seq 0 0 0 0 0.5206827562196897 38.44566514680452 30.0 no