# Supplementary Data 6. HyprColoc results.,,,,,,,,,,,,,,,
# Trait: biomarker trait,,,,,,,,,,,,,,,
# Chr: chromosome,,,,,,,,,,,,,,,
# Base.pairs: position in bp of the lead GWAS SNP,,,,,,,,,,,,,,,
# Lead.SNP: lead GWAS SNP,,,,,,,,,,,,,,,
# A1: tested allele,,,,,,,,,,,,,,,
# A2: non-tested allele,,,,,,,,,,,,,,,
# P_WMH: GWAS p-value for WMH,,,,,,,,,,,,,,,
# P_FA: GWAS p-value for FA,,,,,,,,,,,,,,,
# P_MD: GWAS p-value for MD,,,,,,,,,,,,,,,
# HGNC.genes.: nearest genes to the lead snp and its proxies,,,,,,,,,,,,,,,
# Novel: indicates by yes or no if the association locus has already been described in previous publications,,,,,,,,,,,,,,,
# colocalized_traits: traits which are found colocalized in hyprcoloc,,,,,,,,,,,,,,,
# posterior_prob: posterior probability that all traits are colocalized,,,,,,,,,,,,,,,
# regional_prob: regional association probability,,,,,,,,,,,,,,,
# candidate_snp: candidate causal variant explaining the shared association,,,,,,,,,,,,,,,
# posterior_explained_by_snp: the proportion of the posterior probability explained by the candidate snp,,,,,,,,,,,,,,,
Trait,Chr,Base.pairs,Lead.SNP,A1,A2,P_WMH,P_FA,P_MD,HGNC.genes.,Novel,colocalized_traits,posterior_prob,regional_prob,candidate_snp,posterior_explained_by_snp
FA,2,"217,325,317",rs34380167,CCAAA,C,0.0281,1.16E-08,8.98E-05,"SMARCAL1, RPL37A",Yes,"FA, MD",0.7849,0.8436,rs13015080,0.1487
WMH,3,"183,380,035",rs830179,A,G,4.67E-09,0.321,0.00111,KLHL24,Yes,"WMH, MD",0.4784,0.7113,rs830179,0.0858
"FA, MD",5,"82,862,328",rs35544841,GA,G,6.89E-07,2.72E-25,1.80E-34,VCAN,No,"WMH, FA, MD",0.9924,0.9985,rs67827860,0.8509
WMH,5,"121,510,586",rs17148926,C,A,4.07E-09,0.00154,4.46E-05,CTC-441N14.4,Yes,"WMH, FA, MD, AS, AIS, SVS",0.7542,0.805,rs17433120,0.9999
"FA, MD",5,"139,719,991",rs4150221,C,T,0.83,1.39E-09,4.40E-08,HBEGF,Yes,"FA, MD",0.9693,0.9988,rs2237076,0.2087
FA,6,"26,979,765",rs374598428,CAAAGAGGAGCTGGT ,C,0.0278,1.52E-08,2.01E-07,"LINC00240, VN1R12P",Yes,"FA, MD, LAS",0.6168,0.7889,rs36022097,0.1737
MD,6,"31,329,092",rs7772614,A,C,0.0193,3.54E-05,8.44E-10,"HLA-B, HLA-S",Yes,"FA, MD",0.8347,0.8601,rs2523582,0.4499
WMH,6,"151,016,058",rs275350,C,G,8.83E-17,0.00396,4.54E-05,PLEKHG1,No,"WMH, MD",0.9084,0.9229,rs275350,0.9974
WMH,13,"111,040,681",rs11838776,A,G,7.90E-11,0.197,0.0103,COL4A2,No,"WMH, SVS",0.9969,0.9996,rs11838776,0.8492
WMH,14,"100,581,636",rs11160570,T,C,6.10E-13,0.0109,3.19E-05,"EVL, DEGS2",No,"WMH, MD",0.8971,0.9316,rs11160570,0.4231
FA,16,"89,951,460",rs112730611,T,C,0.0127,1.36E-09,3.86E-06,"SPIRE2, TCF25",Yes,"FA, MD",0.9303,0.9853,rs72813420,0.2603
WMH,17,"43,128,906",rs8071429,T,A,2.61E-16,9.17E-05,4.14E-06,"DCAKD, NMT1",No,"WMH, FA, MD",0.7587,0.931,rs55897749,0.8177