# Supplemental Table S13. A summary of how frequently the motif of a transcription factor is impacted by SNPs with a PIP > 0.1. # Included is: # The name of the transcription factor (geneSymbol) # The frequency that TF is disrupted by a SNP with PIP > 0.1 and overlap with a SCZ enriched population (overlap.snp.freq) # The frequency that TF is disrupted by fine-mapped SNPs in total (all.snp.freq) # The probability of a fine-mapped SNP disrupting that TF (all.snp.prob) # The P-value from an exact binomial test used to test for over-representation of TFs (bionomial.p) geneSymbol overlap.snp.freq all.snp.freq all.snp.prob binomial.p ARNT2 4 176 0.004548156 9.68E-04 ZFX 5 291 0.007519963 0.001572944 HOXA13 5 306 0.00790759 0.002020345 NR4A1 4 214 0.005530144 0.002264919 WT1 5 339 0.008760369 0.003337408 MBD2 2 74 0.001912293 0.003945315 EGR4 5 366 0.009458098 0.004821547 PPARG 5 393 0.010155826 0.006742544 CEBPB 3 179 0.004625682 0.007251062 GLIS3 3 189 0.0048841 0.008727542 E2F3 1 33 8.53E-04 0.008766183 HIVEP2 2 106 0.00273923 0.010518615 PPARA 4 324 0.008372742 0.012500579 GLI1 4 326 0.008424426 0.012806269 THRA 5 456 0.011783859 0.013293522 MAX 2 118 0.003049332 0.013991986 NR4A2 3 220 0.005685195 0.014508818 SMAD2 3 221 0.005711037 0.014727301 TEF 4 340 0.008786211 0.015088743 TCF3 3 225 0.005814404 0.015622021 USF1 2 126 0.003256066 0.016627566 E2F2 1 47 0.001214564 0.01711346 MYC 2 128 0.00330775 0.017326891 HINFP 1 48 0.001240406 0.017800779 TCF4 4 358 0.009251363 0.018403727 STAT5A 2 134 0.003462801 0.019522389 SPZ1 2 140 0.003617852 0.021864551 PPARD 3 250 0.006460449 0.021987341 ELK3 2 141 0.003643693 0.022269191 EGR1 2 146 0.003772902 0.024353595 NHLH1 3 259 0.006693025 0.024614398 NRF1 2 148 0.003824586 0.025215907 E2F5 1 60 0.001550508 0.026919318 ZBTB7A 2 155 0.004005478 0.028362257 MECP2 1 62 0.001602191 0.02858807 PTF1A 3 273 0.00705481 0.029063668 E2F7 1 63 0.001628033 0.029437649 HAND1 2 160 0.004134687 0.030731441 EGR2 3 279 0.007209861 0.031107276 EOMES 2 163 0.004212213 0.032201462 ESR1 2 163 0.004212213 0.032201462 SP4 5 562 0.01452309 0.032622671 TP63 2 165 0.004263896 0.033201617 NR2C2 3 301 0.007778381 0.039310594 ZIC2 2 177 0.004573998 0.03953841 EBF1 2 180 0.004651523 0.041211785 CEBPA 2 181 0.004677365 0.041777429 NFIA+NFIB+NFIC+NFIX 2 188 0.004858258 0.045846086 PAX2 2 188 0.004858258 0.045846086 REST 3 320 0.008269375 0.047298175 FOXI1 2 191 0.004935783 0.047647809 XBP1 1 83 0.002144869 0.048403426 ESRRG 2 193 0.004987467 0.048868121 TFAP2A 2 193 0.004987467 0.048868121 NFIL3 2 194 0.005013309 0.049483998 BHLHE41 2 195 0.00503915 0.050103677 ENO1 1 85 0.002196553 0.050491314 MECOM 4 477 0.012326537 0.052365004 MAZ 6 802 0.020725121 0.054375273 ESRRB 2 203 0.005245885 0.055196795 PLAG1 4 486 0.012559113 0.055839653 ZNF589 1 95 0.002454971 0.061396778 CDX1 3 357 0.009225521 0.06524025 SP1 4 509 0.013153474 0.065311581 HOXA1 2 218 0.005633512 0.065382084 MYCN 1 100 0.00258418 0.067123382 CTCF 2 225 0.005814404 0.070410288 NR4A3 2 227 0.005866088 0.071878202 THRB 3 371 0.009587307 0.072836257 FOSL1 1 105 0.002713389 0.073019423 TWIST1 3 373 0.00963899 0.073956778 CXXC1 1 106 0.00273923 0.074218126 NEUROD1 2 231 0.005969455 0.074855088 PITX2 2 232 0.005995297 0.075607788 TFAP2C 2 233 0.006021139 0.076363853 POU4F2 2 235 0.006072822 0.077886027 TFAP2B 1 110 0.002842598 0.079075448 NR5A2 1 111 0.002868439 0.080305042 PLAGL1 1 111 0.002868439 0.080305042 TFCP2 1 111 0.002868439 0.080305042 USF2 1 113 0.002920123 0.082782044 MYOD1 2 246 0.006357082 0.086492885 NFKB1 1 116 0.002997648 0.08654102 E2F4 1 118 0.003049332 0.089075174 HOXB1 1 118 0.003049332 0.089075174 ARNT 1 120 0.003101016 0.091631224 CREM 1 121 0.003126857 0.092917291 EGR3 2 257 0.006641342 0.095483964 ESRRA 2 259 0.006693025 0.097158522 NR1H4 1 125 0.003230225 0.098113618 STAT6 1 126 0.003256066 0.099425386 ZNF350 2 262 0.006770551 0.099692754 OVOL1 1 127 0.003281908 0.100742099 HESX1 1 128 0.00330775 0.102063692 STAT4 2 265 0.006848076 0.102253511 ZIC1 2 265 0.006848076 0.102253511 VSX2 1 129 0.003333592 0.103390103 TFAP2D 3 422 0.010905238 0.104064691 ETS2 1 132 0.003411117 0.107397606 LHX2 2 273 0.00705481 0.10920886 REL 1 134 0.003462801 0.110092213 IKZF1 3 431 0.011137814 0.110124834 RUNX3 2 276 0.007132336 0.111863474 TP53 2 276 0.007132336 0.111863474 NR2F2 3 435 0.011241181 0.112868223 RXRB 2 278 0.007184019 0.113646941 BHLHE40 1 138 0.003566168 0.115534277 NFYB 1 145 0.00374706 0.12521753 SOX2 3 453 0.011706334 0.125582262 JUND 1 147 0.003798744 0.128019235 NFKB2 1 147 0.003798744 0.128019235 HOXB7 2 297 0.007675014 0.131113406 KLF4 3 462 0.01193891 0.132157953 KLF6 1 151 0.003902111 0.133666473 IRF2 4 639 0.016512908 0.134222141 DBP 2 301 0.007778381 0.13490545 E2F1 1 153 0.003953795 0.136511131 GCM1 1 153 0.003953795 0.136511131 PBX3 1 154 0.003979637 0.137938532 STAT5B 1 155 0.004005478 0.139369242 NFYC 1 157 0.004057162 0.142240384 NR2C1 1 163 0.004212213 0.150927869 ONECUT1 2 318 0.008217691 0.151431145 TBP 3 488 0.012610797 0.151922038 ZBTB6 1 164 0.004238055 0.152386051 NR3C1 2 321 0.008295217 0.1544126 CEBPZ 1 166 0.004289738 0.155310773 MAFA 2 325 0.008398584 0.158416572 RARA 1 169 0.004367264 0.159718015 GLI2 1 171 0.004418947 0.16266906 TCF12 2 330 0.008527793 0.163466291 RARG 2 332 0.008579476 0.165499713 MLXIPL 1 174 0.004496473 0.167114013 NANOG 1 175 0.004522314 0.168600382 ELF3 2 343 0.008863736 0.176815307 MTF1 1 181 0.004677365 0.177564978 HIVEP1 1 182 0.004703207 0.179066394 INSM1 1 182 0.004703207 0.179066394 FOSB 1 183 0.004729049 0.180569786 SOX15 1 183 0.004729049 0.180569786 ZBTB4 2 347 0.008967103 0.180982808 HLF 1 184 0.004754891 0.182075109 NR2F1 2 349 0.009018787 0.1830766 ALX1 2 351 0.009070471 0.185176927 TFAP4 1 187 0.004832416 0.186602247 ARID3A 10 1919 0.049590408 0.187457901 ZNF423 1 188 0.004858258 0.188114876 NKX2-2 2 355 0.009173838 0.189396718 MAFK 1 190 0.004909941 0.191145263 TCF7L2 1 192 0.004961625 0.194182216 RFX3 1 194 0.005013309 0.197225414 CEBPD 1 195 0.00503915 0.198749256 FOXF2 3 546 0.014109621 0.19960718 DLX2 1 197 0.005090834 0.20180123 AIRE 1 200 0.005168359 0.206389343 STAT3 1 201 0.005194201 0.207921269 MYOG 1 202 0.005220043 0.20945441 ZNF384 2 375 0.009690674 0.210848054 SOX17 2 384 0.00992325 0.220672156 GLI3 1 210 0.005426777 0.221758902 HNF4G 1 213 0.005504303 0.226388781 PBX2 1 213 0.005504303 0.226388781 IRF1 3 577 0.014910717 0.226755755 FOXA3 2 392 0.010129984 0.229482007 POU6F1 2 392 0.010129984 0.229482007 NR3C2 1 218 0.005633512 0.234120597 MEF2C 2 398 0.010285035 0.23613273 IRF8 3 592 0.015298344 0.24022157 TCF7 1 222 0.005736879 0.240317483 RREB1 2 405 0.010465928 0.243934563 NFE2 1 225 0.005814404 0.24497047 SMAD4 1 226 0.005840246 0.246522312 HOXB8 2 408 0.010543453 0.247291209 SPIB 2 408 0.010543453 0.247291209 ZNF148 2 411 0.010620978 0.250655145 EHF 1 231 0.005969455 0.254286504 OTX2 1 232 0.005995297 0.255840129 TGIF1 1 234 0.00604698 0.258947933 TLX1 2 419 0.010827713 0.25965864 BACH1 1 235 0.006072822 0.260502053 RXRA 1 235 0.006072822 0.260502053 ESR2 1 237 0.006124506 0.263610589 RARB 1 237 0.006124506 0.263610589 MITF 1 238 0.006150348 0.265164948 GATA5 1 239 0.006176189 0.266719332 NFATC2 2 426 0.011008605 0.267572072 CDC5L 1 241 0.006227873 0.269828061 RBPJ 1 249 0.006434607 0.282258547 TEAD1 1 261 0.006744709 0.300868542 SOX9 1 263 0.006796392 0.303963551 FEV 1 271 0.007003127 0.316317907 NFE2L2 1 272 0.007028969 0.317858957 KLF3 1 275 0.007106494 0.322477277 HBP1 1 276 0.007132336 0.32401504 SPI1 2 482 0.012455746 0.331568683 EPAS1 1 283 0.007313228 0.33475387 NR1H2 1 283 0.007313228 0.33475387 ETS1 1 291 0.007519963 0.346966097 PURA 2 497 0.012843373 0.348765211 ARID5B 1 293 0.007571646 0.350008004 PRDM1 2 503 0.012998424 0.355633772 NFAT5 1 297 0.007675014 0.356077474 ELF2 1 298 0.007700855 0.357591755 NR2F6 1 304 0.007855906 0.366650278 SMAD1 1 307 0.007933432 0.371161373 NFATC3 1 317 0.008191849 0.386104774 HOXC8 1 318 0.008217691 0.387590833 POU3F1 1 321 0.008295217 0.392039597 KLF8 1 324 0.008372742 0.39647397 ATF5 1 326 0.008424426 0.399422055 ZBTB7B 3 764 0.019743133 0.401993132 MEF2A 2 548 0.014161304 0.406739445 PROP1 2 555 0.014342197 0.414595642 KLF15 4 1007 0.026022689 0.418883087 CEBPG 1 341 0.008812053 0.421314425 TEAD3 1 343 0.008863736 0.424203099 SOX4 1 344 0.008889578 0.425644667 SP2 1 350 0.009044629 0.43425468 BARX2 1 351 0.009070471 0.435683027 TBX3 2 574 0.014833191 0.435749335 SOX18 1 353 0.009122154 0.438533932 T 1 353 0.009122154 0.438533932 IRF3 3 816 0.021086906 0.450761298 FOXA1 1 365 0.009432256 0.455473623 POU2F2 1 372 0.009613148 0.465220097 IRF7 2 611 0.015789338 0.476090932 SP3 1 381 0.009845724 0.477600122 FOXC1 1 383 0.009897408 0.480327704 HOXD4 1 386 0.009974933 0.484402813 POU1F1 2 622 0.016073597 0.48783371 MEF2D 2 625 0.016151123 0.491014542 HNF1B 1 393 0.010155826 0.493834698 ZNF219 1 425 0.010982764 0.535542047 TEAD4 1 432 0.011163656 0.544348925 POU2F1 1 448 0.011577125 0.564042537 IRF4 4 1211 0.031294416 0.580057202 PAX5 1 496 0.012817531 0.619431531 FOXC2 1 530 0.013696152 0.655309999 FOXQ1 1 533 0.013773678 0.658343554 POU5F1 1 537 0.013877045 0.662355259 FOXJ3 7 2154 0.05566323 0.691453709 IRF9 2 847 0.021888002 0.694615432 POU3F2 1 624 0.016125281 0.74056349 FOXD3 1 637 0.016461224 0.750828503 FOXO1 1 699 0.018063416 0.795120755 ZNF143 1 718 0.01855441 0.807238742 FUBP1 1 794 0.020518386 0.849588102 ONECUT2 1 874 0.02258573 0.884912624 HOXC6 1 916 0.023671086 0.900242061 IRF5 2 1339 0.034602166 0.923479411 FOXJ2 1 1022 0.026410316 0.930910151