#FlyBaseID	GeneSymbol	log2FoldChange	pvalue	padj	ortholog_human_NCBI	ortholog_human_DIOPT	ortholog_human_DIOPT_evidence	is_TF	is_transmembrane_protein	is_GPCR	function_summary
FBgn0029762	NAAT1	-1.156409394	0.005503048	0.999936032	NA	SLC6A5	moderate	NA	transmembrane protein	NA	"The gene Nutrient Amino Acid Transporter 1 is referred to in FlyBase by the symbol Dmel\NAAT1 (CG3252, FBgn0029762). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:5405238..5410849. It has the cytological map location 4F9. Protein features are: Sodium:neurotransmitter symporter. Its molecular function is described by: sodium:amino acid symporter activity; D-amino acid transmembrane transporter activity; neurotransmitter transporter activity; neutral amino acid transmembrane transporter activity; L-amino acid transmembrane transporter activity; neurotransmitter:sodium symporter activity; cation:amino acid symporter activity. It is involved in the biological process described with: sodium ion transport; neurotransmitter transport; amino acid transmembrane import; neutral amino acid transport; L-amino acid transport; D-amino acid transport. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during late larval stages, in adult male stages.  "
FBgn0033904	CG18327	-1.154979301	0.00598379	0.999936032	SLC25A34	SLC25A34;SLC25A35	high;moderate	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG18327 (FBgn0033904). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:14166982..14168233. It has the cytological map location 50E1. Protein features are: Mitochondrial carrier domain; Mitochondrial substrate/solute carrier. Its molecular function is described by: transmembrane transporter activity. It is involved in the biological process described with: mitochondrial transport. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed in adult male stages.
FBgn0038742	Arc42	-1.144106243	0.006366291	0.999936032	ACADS	ACADS;ACADSB	high;low	Co-factor	NA	NA	"The gene Arc42 is referred to in FlyBase by the symbol Dmel\Arc42 (CG4703, FBgn0038742). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:19877737..19879309. It has the cytological map location 92B4. Protein features are: Acyl-CoA dehydrogenase, conserved site; Acyl-CoA dehydrogenase/oxidase C-terminal; Acyl-CoA dehydrogenase/oxidase, N-terminal; Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain; Acyl-CoA oxidase/dehydrogenase, central domain. Its molecular function is described by: RNA polymerase II transcription cofactor activity; acyl-CoA dehydrogenase activity; flavin adenine dinucleotide binding. It is involved in the biological process described with: dendrite morphogenesis; oxidation-reduction process; transcription initiation from RNA polymerase II promoter. 6 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: visible; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0003388	shd	-1.141222595	0.00600453	0.999936032	NA	CYP24A1	moderate	NA	NA	NA	"The gene shade is referred to in FlyBase by the symbol Dmel\shd (CG13478, FBgn0003388). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:14614458..14622205. It has the cytological map location 70E4. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Its molecular function is described by: heme binding; ecdysone 20-monooxygenase activity; iron ion binding. It is involved in the biological process described with: oxidation-reduction process; growth of a germarium-derived egg chamber; border follicle cell migration; head involution; central nervous system development; pupation; ecdysteroid biosynthetic process; midgut development; dorsal closure. 13 alleles are reported. The phenotypes of these alleles manifest in: foregut; tracheal system; dorsal closure embryo; neuropil associated CNS glial cell; tract; sensory neuron; epithelial cell; head; presumptive embryonic/larval digestive system; germline cyst. The phenotypic classes of alleles include: developmental rate defective; female sterile; female semi-fertile; viable; lethal - all die before end of embryonic stage; some die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during late larval stages.  "
FBgn0037819	CG14688	-1.12947358	0.007011889	0.999936032	PHYHD1	PHYHD1	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG14688 (FBgn0037819). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:10677737..10680925. It has the cytological map location 86C4. Protein features are: Phytanoyl-CoA dioxygenase. Its molecular function is described by: phytanoyl-CoA dioxygenase activity. It is involved in the biological process described with: fatty acid alpha-oxidation. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed during early pupal stages.
FBgn0035667	Jon65Ai	-1.119702085	0.006126873	0.999936032	NA	F9;PROC	low;low	NA	NA	NA	"The gene Jonah 65Ai is referred to in FlyBase by the symbol Dmel\Jon65Ai (CG10475, FBgn0035667). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:6053493..6054443. It has the cytological map location 65A4. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of extremely low expression.  Peak expression observed during late larval stages.  "
FBgn0002563	Lsp1beta	-1.118007368	0.00651137	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Larval serum protein 1 ‘_ is referred to in FlyBase by the symbol Dmel\Lsp1‘_ (CG4178, FBgn0002563). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:898500..901316. It has the cytological map location 21E2. Protein features are: Hemocyanin, C-terminal; Hemocyanin, N-terminal; Hemocyanin/hexamerin; Hemocyanin/hexamerin middle domain; Immunoglobulin E-set; Uncharacterised domain, di-copper centre. Its molecular function is unknown. It is involved in the biological process described with: lateral inhibition. 9 alleles are reported. The phenotypes of these alleles manifest in: egg; chaeta. The phenotypic classes of alleles include: visible; viable; electrophoretic variant. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period.  "
FBgn0050272	MFS1	-1.115491014	0.007500438	0.999936032	NA	SLC17A5;SLC17A4;SLC17A3;SLC17A2;SLC17A1;SLC17A6;SLC17A8;SLC17A7	moderate;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene Major Facilitator Superfamily Transporter 1 is referred to in FlyBase by the symbol Dmel\MFS1 (CG30272, FBgn0050272). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:22829644..22831877. It has the cytological map location 59B2. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain. Its molecular function is described by: transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; anion transport. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 06-18 hour embryonic stages.  "
FBgn0031645	CG3036	-1.102635741	0.007379933	0.999936032	NA	SLC17A5;SLC17A4;SLC17A3;SLC17A2;SLC17A1;SLC17A6;SLC17A8;SLC17A7	moderate;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3036 (FBgn0031645). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:4892112..4903889. It has the cytological map location 25B1-25B2. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain. Its molecular function is described by: transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; anion transport. 23 alleles are reported. The phenotype of these alleles manifest in: rhabdomere R7. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0039324	CG10553	-1.096676097	0.008936993	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG10553 (FBgn0039324). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:25316461..25318111. It has the cytological map location 96D1. Protein features are: CHK kinase-like; Protein kinase-like domain; Protein of unknown function DUF227. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed in adult male stages.
FBgn0002868	MtnA	-1.083778824	0.00759504	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Metallothionein A is referred to in FlyBase by the symbol Dmel\MtnA (CG9470, FBgn0002868). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:9783407..9784370. It has the cytological map location 85E9. Protein features are: Metallothionein, family 5, Diptera. Its molecular function is described by: metal ion binding. It is involved in the biological process described with: metal ion homeostasis; response to metal ion. 21 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; chaeta; trichogen cell. The phenotypic classes of alleles include: chemical sensitive; viable; visible; body color defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, in adult male stages.  "
FBgn0033518	Prx2540-2	-1.081748663	0.009623081	0.999936032	NA	PRDX6	moderate	NA	NA	NA	"The gene Peroxiredoxin 2540-2 is referred to in FlyBase by the symbol Dmel\Prx2540-2 (CG11765, FBgn0033518). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:10418718..10419761. It has the cytological map location 47A7. Protein features are: Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant; Peroxiredoxin, AhpC-type; Peroxiredoxin, C-terminal; Thioredoxin domain; Thioredoxin-like fold. Its molecular function is described by: peroxidase activity; peroxiredoxin activity. It is involved in the biological process described with: hydrogen peroxide catabolic process; oxidation-reduction process; cell redox homeostasis. 5 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0032618	CG31743	-1.060514045	0.009380781	0.999936032	NA	CHST11;CHST13;CHST14;CHST12;CHST8;CHST9;CHST10	high;moderate;moderate;moderate;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31743 (FBgn0032618). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:16879517..16886319. It has the cytological map location 36B3. Protein features are: Carbohydrate sulfotransferase 8-10; Sulfotransferase. Its molecular function is described by: sulfotransferase activity. It is involved in the biological process described with: carbohydrate biosynthetic process. 5 alleles are reported. The phenotype of these alleles manifest in: wing vein. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed at stages throughout the larval period, during late pupal stages, in adult male stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0030218	CG1628	-1.057342771	0.011433663	0.999936032	SLC25A15	SLC25A15;SLC25A2	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1628 (FBgn0030218). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:10598146..10602714. It has the cytological map location 9D3-9D4. Protein features are: Mitochondrial carrier domain; Mitochondrial substrate/solute carrier. Its molecular function is described by: L-ornithine transmembrane transporter activity; amino acid transmembrane transporter activity. It is involved in the biological process described with: mitochondrial ornithine transport; mitochondrial transport; amino acid transmembrane transport. 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, in adult male stages.  "
FBgn0034647	pirk	-1.046509268	0.009950343	0.999936032	NA	NA	NA	NA	NA	NA	"The gene poor Imd response upon knock-in is referred to in FlyBase by the symbol Dmel\pirk (CG15678, FBgn0034647). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:21660967..21662995. It has the cytological map location 57F6-57F7. Its molecular function is described by: receptor binding; protein binding. It is involved in the biological process described with: negative regulation of innate immune response; response to symbiotic bacterium; negative regulation of peptidoglycan recognition protein signaling pathway; negative regulation of immune response. 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: immune response defective; viable; short lived; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during late larval stages, during late pupal stages.  "
FBgn0027073	CG4302	-1.030785572	0.010585382	0.999936032	NA	UGT2B10;UGT2A2;UGT2B11;UGT1A3;UGT2B4;UGT2B15;UGT2B17;UGT2A3;UGT2B7;UGT8;UGT1A6;UGT1A1;UGT2B28;UGT3A1;UGT3A2;UGT1A4;UGT1A10;UGT1A7;UGT1A5;UGT1A9;UGT1A8	high;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4302 (FBgn0027073). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:21212880..21214972. It has the cytological map location 57D1-57D2. Protein features are: UDP-glucuronosyl/UDP-glucosyltransferase; UDP-glycosyltransferase family, conserved site. Its molecular function is described by: UDP-glycosyltransferase activity; glucuronosyltransferase activity. It is involved in the biological process described with: UDP-glucose metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during early larval stages.  "
FBgn0263507	CR43496	-1.022788226	0.014618722	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR43496 (FBgn0263507). It is a non_protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts. Gene sequence location is X:6758610..6759491. It has the cytological map location 6C12. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available.
FBgn0031970	CG7227	-1.013645377	0.015693164	0.999936032	NA	CD36;SCARB1;SCARB2	moderate;moderate;low	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG7227 (FBgn0031970). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:7994388..7998151. It has the cytological map location 28D3. Protein features are: CD36 family. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages.
FBgn0035697	CG10163	-1.013456455	0.015897584	0.999936032	NA	PNLIPRP1;PNLIPRP2;LIPI;PNLIPRP3;PNLIP;LIPH;PLA1A;PDE6D	low;low;low;low;low;low;low;low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG10163 (FBgn0035697). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:6257423..6258760. It has the cytological map location 65A10-65A11. Protein features are: Alpha/Beta hydrolase fold; Lipase/vitellogenin; Triacylglycerol lipase family. Its molecular function is described by: carboxylic ester hydrolase activity. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed in adult female stages.
FBgn0031735	CG11029	-1.006226226	0.013294872	0.999936032	NA	PLB1	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11029 (FBgn0031735). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:5746157..5747961. It has the cytological map location 25F4. Protein features are: GDSL lipase/esterase; Lipase, GDSL, active site; Phospholipase B; SGNH hydrolase-type esterase domain. Its molecular function is described by: lipase activity. It is involved in the biological process described with: lipid metabolic process. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during early pupal stages.  "
FBgn0039777	Jon99Fii	-1.001871383	0.012054329	0.999936032	NA	PROC	low	DNA-binding with transcription factor activity	NA	NA	"The gene Jonah 99Fii is referred to in FlyBase by the symbol Dmel\Jon99Fii (CG2229, FBgn0039777). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:30487016..30487928. It has the cytological map location 99F6. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity; endopeptidase activity. It is involved in the biological process described with: proteolysis. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of no expression detected.  Peak expression observed during early larval stages.  "
FBgn0001187	Hex-C	-0.991977233	0.016090238	0.999936032	NA	GCK;HK1;HKDC1;HK3;HK2	moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"The gene Hexokinase C is referred to in FlyBase by the symbol Dmel\Hex-C (CG8094, FBgn0001187). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:15218837..15220329. It has the cytological map location 51E7. Protein features are: Hexokinase; Hexokinase, C-terminal; Hexokinase, N-terminal. Its molecular function is described by: ATP binding; hexokinase activity; mannokinase activity; glucokinase activity; glucose binding; fructokinase activity. It is involved in the biological process described with: glycolytic process; carbohydrate phosphorylation; regulation of glucose metabolic process; cellular glucose homeostasis; lateral inhibition. 14 alleles are reported. The phenotypes of these alleles manifest in: germarium; trichogen cell; tormogen cell; chaeta. The phenotypic classes of alleles include: viable; visible; size defective; increased cell death; electrophoretic variant. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed in adult male stages.  "
FBgn0035985	Cpr67B	-0.981919319	0.016374771	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Cuticular protein 67B is referred to in FlyBase by the symbol Dmel\Cpr67B (CG3672, FBgn0035985). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:9404797..9406174. It has the cytological map location 67B4. Protein features are: Insect cuticle protein. Its molecular function is described by: structural constituent of chitin-based larval cuticle; structural constituent of cuticle. It is involved in the biological process described with: chitin-based cuticle development; sleep. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0028948	CG15253	-0.97487816	0.016960262	0.999936032	NA	MEP1B;CUBN;TLL1;BMP1;MEP1A;ASTL;TLL2	moderate;low;low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15253 (FBgn0028948). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:15615357..15616351. It has the cytological map location 35D3. Protein features are: Astacin-like metallopeptidase domain; Metallopeptidase, catalytic domain; Peptidase M12A; Peptidase, metallopeptidase. Its molecular function is described by: metalloendopeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0003067	Pepck	-0.953997743	0.02313841	0.999936032	PCK2	PCK2;PCK1	high;moderate	NA	NA	NA	"The gene Phosphoenolpyruvate carboxykinase is referred to in FlyBase by the symbol Dmel\Pepck (CG17725, FBgn0003067). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:18536767..18539416. It has the cytological map location 55D3. Protein features are: Phosphoenolpyruvate carboxykinase, C-terminal; Phosphoenolpyruvate carboxykinase, GTP-utilising; Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal; Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal; Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site; Phosphoenolpyruvate carboxykinase, N-terminal. Its molecular function is described by: phosphoenolpyruvate carboxykinase (GTP) activity; GTP binding. It is involved in the biological process described with: gluconeogenesis. 7 alleles are reported. The phenotypes of these alleles manifest in: segment of leg; germarium; leg. The phenotypic classes of alleles include: viable; size defective; increased cell death; lethal - all die before end of P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0266488	CG45087	-0.953997743	0.02313841	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG45087 (FBgn0266488). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:18536767..18539416. It has the cytological map location 55D3. Its molecular function is described by: . It is involved in the biological process described with: . One allele is reported. No phenotypic data is available. No phenotypic class data is available.
FBgn0051091	CG31091	-0.94541651	0.017121347	0.999936032	NA	LIPK;LIPJ;LIPF;LIPN;LIPA;LIPM	moderate;moderate;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31091 (FBgn0051091). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:25899903..25902172. It has the cytological map location 96F7. Protein features are: Alpha/Beta hydrolase fold; Lipase, eukaryotic; Partial AB-hydrolase lipase domain. Its molecular function is described by: hydrolase activity, acting on ester bonds. It is involved in the biological process described with: lipid metabolic process. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed during late larval stages.  "
FBgn0035287	CG13937	-0.941363223	0.02501981	0.999936032	NA	CHST8;CHST9;CHST10	high;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13937 (FBgn0035287). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (3 unique). Gene sequence location is 3L:1876551..1883041. It has the cytological map location 62B7-62B9. Protein features are: Carbohydrate sulfotransferase 8-10; Sulfotransferase; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: sulfotransferase activity. It is involved in the biological process described with: carbohydrate biosynthetic process. 4 alleles are reported. The phenotype of these alleles manifest in: wing vein. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during late pupal stages, in adult male stages.  "
FBgn0039754	CG9747	-0.938499366	0.025121793	0.999936032	NA	SCD;SCD5	moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9747 (FBgn0039754). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:30185423..30191252. It has the cytological map location 99E1-99E2. Protein features are: Acyl-CoA desaturase; Fatty acid desaturase domain. Its molecular function is described by: oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water. It is involved in the biological process described with: oxidation-reduction process; lipid metabolic process. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: increased mortality; phenotype; increased mortality during development; lethal - all die before end of P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during early pupal stages.  "
FBgn0038415	CG17929	-0.937632862	0.02274103	0.999936032	NA	SLC2A12;SLC2A13;SLC2A8;SLC2A6;SLC2A10	low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17929 (FBgn0038415). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:16325492..16327331. It has the cytological map location 89B12. Protein features are: Major facilitator superfamily domain; Major facilitator,  sugar transporter-like. Its molecular function is described by: transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed in adults stages of both sexes.  "
FBgn0026150	ApepP	-0.932721863	0.019582703	0.999936032	XPNPEP1	XPNPEP1;XPNPEP2	high;moderate	NA	NA	NA	"The gene Aminopeptidase P is referred to in FlyBase by the symbol Dmel\ApepP (CG6291, FBgn0026150). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:16908229..16910418. It has the cytological map location 36B4. Protein features are: Aminopeptidase P; Creatinase, N-terminal; Creatinase/Aminopeptidase P, N-terminal; Creatinase/Aminopeptidase P/Spt16, N-terminal; Peptidase M24; Peptidase M24, C-terminal domain. Its molecular function is described by: metalloaminopeptidase activity. It is involved in the biological process described with: proteolysis. 5 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0038799	MFS9	-0.930136428	0.024593233	0.999936032	NA	SLC17A5;SLC17A6;SLC17A8;SLC17A7	moderate;low;low;low	NA	transmembrane protein	NA	"The gene Major Facilitator Superfamily Transporter 9 is referred to in FlyBase by the symbol Dmel\MFS9 (CG4288, FBgn0038799). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:20507392..20512468. It has the cytological map location 92E14. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain. Its molecular function is described by: transmembrane transporter activity. It is involved in the biological process described with: anion transport; transmembrane transport. 7 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; fertile; lethal - all die during P-stage; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during early larval stages.  "
FBgn0038873	CG5892	-0.922885799	0.016903627	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5892 (FBgn0038873). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:21242618..21245418. It has the cytological map location 93D1. Protein features are: Acyltransferase 3; Nose resistant-to-fluoxetine protein, N-terminal. Its molecular function is described by: transferase activity, transferring acyl groups other than amino-acyl groups. The biological processes in which it is involved are not known. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0035791	CG8539	-0.920061618	0.024582705	0.999936032	NA	CPA2;CPA5;CPA4;CPA1;CPO;CPA3;CPB2;CPA6;CPB1	moderate;moderate;moderate;moderate;low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8539 (FBgn0035791). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:7497211..7498831. It has the cytological map location 66A2. Protein features are: Insect gut carboxypeptidase-like, carboxypeptidase domain; Peptidase M14, carboxypeptidase A. Its molecular function is described by: metallocarboxypeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis. 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during early pupal stages.  "
FBgn0035887	Jon66Cii	-0.900617996	0.030357115	0.999936032	NA	C1S;F9;PROC	low;low;low	NA	NA	NA	"The gene Jonah 66Cii is referred to in FlyBase by the symbol Dmel\Jon66Cii (CG7170, FBgn0035887). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:8392820..8393649. It has the cytological map location 66C10. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of no expression detected.  Peak expression observed during late larval stages.  "
FBgn0032144	CG17633	-0.899445972	0.021068421	0.999936032	CPA1	CPB1;CPA1;CPO;CPA3;CPB2;CPA2;CPA6;CPA5;CPA4	high;high;moderate;moderate;moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17633 (FBgn0032144). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:9769060..9770409. It has the cytological map location 30C8. Protein features are: Carboxypeptidase, activation peptide; Insect gut carboxypeptidase-like, carboxypeptidase domain; Peptidase M14, carboxypeptidase A; Protease propeptides/proteinase inhibitor I9. Its molecular function is described by: metallocarboxypeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis. 5 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; ganglion mother cell; embryonic/larval neuroblast; trichogen cell. The phenotypic classes of alleles include: neuroanatomy defective; partially lethal - majority die; some die during pupal stage; lethal; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very low expression.  Peak expression observed during late larval stages.  "
FBgn0264272	mwh	-0.888800218	0.034334922	0.999936032	NA	FMNL1	moderate	NA	NA	NA	"The gene multiple wing hairs is referred to in FlyBase by the symbol Dmel\mwh (CG43772, FBgn0264272). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3L:1200786..1232700. It has the cytological map location 61F3. Protein features are: Armadillo-like helical; Armadillo-type fold; Formin, FH3 domain; Formin, GTPase-binding domain; Rho GTPase-binding/formin homology 3 (GBD/FH3) domain. Its molecular function is described by: protein binding; Rho GTPase binding; actin binding. It is involved in the biological process described with: imaginal disc-derived wing morphogenesis; imaginal disc-derived wing hair site selection; Wnt signaling pathway; negative regulation of actin filament polymerization; establishment of planar polarity; imaginal disc-derived wing hair organization. 26 alleles are reported. The phenotypes of these alleles manifest in: wing; wing cell; mesothoracic tergum; actin filament; trichogen cell; denticle belt; abdominal sternite bristle; microchaeta; wing hair. The phenotypic classes of alleles include: body color defective; visible; viable; locomotor behavior defective; planar polarity defective."
FBgn0027341	Gfat1	-0.888434142	0.024644377	0.999936032	NA	GFPT2;GFPT1	high;moderate	NA	NA	NA	"The gene Glutamine:fructose-6-phosphate aminotransferase 1 is referred to in FlyBase by the symbol Dmel\Gfat1 (CG12449, FBgn0027341). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (8 unique). Gene sequence location is 3R:4126442..4137882. It has the cytological map location 81F. Protein features are: GlmS/AgaS, SIS domain 1; GlmS/FrlB, SIS domain 2; Glucosamine-fructose-6-phosphate aminotransferase, isomerising; Glutamine amidotransferase type 2 domain; Nucleophile aminohydrolases, N-terminal; Sugar isomerase (SIS). Its molecular function is described by: carbohydrate derivative binding; glutamine-fructose-6-phosphate transaminase (isomerizing) activity. It is involved in the biological process described with: fructose 6-phosphate metabolic process; protein N-linked glycosylation; UDP-N-acetylglucosamine metabolic process. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages, during early pupal stages.  "
FBgn0003257	r-l	-0.88645752	0.031105033	0.999936032	UMPS	UMPS	high	NA	NA	NA	"The gene rudimentary-like is referred to in FlyBase by the symbol Dmel\r-l (CG3593, FBgn0003257). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:21070557..21073319. It has the cytological map location 93B10. Protein features are: Aldolase-type TIM barrel; Orotate phosphoribosyl transferase domain; Orotate phosphoribosyltransferase; Orotidine 5'-phosphate decarboxylase; Orotidine 5'-phosphate decarboxylase domain; Orotidine 5'-phosphate decarboxylase, active site; Phosphoribosyltransferase domain; Phosphoribosyltransferase-like; Ribulose-phosphate binding barrel. Its molecular function is described by: orotidine-5'-phosphate decarboxylase activity; orotate phosphoribosyltransferase activity. It is involved in the biological process described with: 'de novo' UMP biosynthetic process; sleep; 'de novo' pyrimidine nucleobase biosynthetic process. 18 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed during early larval stages.  "
FBgn0039049	CG6726	-0.886255272	0.025677459	0.999936032	ACY1	ACY1;ABHD14A;ABHD14A-ACY1;PM20D1	moderate;moderate;moderate;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6726 (FBgn0039049). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:23091724..23095184. It has the cytological map location 94D13. Protein features are: N-acyl-L-amino-acid amidohydrolase; Peptidase M20; Peptidase M20, dimerisation domain. Its molecular function is described by: aminoacylase activity. It is involved in the biological process described with: cellular amino acid metabolic process. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed during late larval stages.  "
FBgn0034715	Oatp58Db	-0.876157721	0.032134757	0.999936032	NA	SLCO2B1;SLCO2A1;SLCO1C1;SLCO1B3;SLCO1B1;SLCO1A2;SLCO1B7;SLCO3A1;SLCO6A1;SLCO5A1;SLCO4C1	high;moderate;moderate;moderate;moderate;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene Organic anion transporting polypeptide 58Db is referred to in FlyBase by the symbol Dmel\Oatp58Db (CG3382, FBgn0034715). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:22221180..22223499. It has the cytological map location 58D2. Protein features are: Major facilitator superfamily domain; Organic anion transporter polypeptide OATP. Its molecular function is described by: transmembrane transporter activity; active transmembrane transporter activity; sodium-independent organic anion transmembrane transporter activity. It is involved in the biological process described with: sodium-independent organic anion transport; organic substance transport; excretion. 6 alleles are reported. The phenotype of these alleles manifest in: Malpighian tubule. The phenotypic classes of alleles include: flight defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed in adult male stages.  "
FBgn0039052	CG6733	-0.874921745	0.036359092	0.999936032	ACY1	ACY1;PM20D1;ABHD14A-ACY1	moderate;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6733 (FBgn0039052). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:23097728..23099191. It has the cytological map location 94D13. Protein features are: N-acyl-L-amino-acid amidohydrolase; Peptidase M20; Peptidase M20, dimerisation domain. Its molecular function is described by: aminoacylase activity. It is involved in the biological process described with: cellular amino acid metabolic process. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 06-18 hour embryonic stages.  "
FBgn0032082	CG18088	-0.872151604	0.026327828	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG18088 (FBgn0032082). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:8967535..8970627. It has the cytological map location 29F6. Protein features are: Alkaline phosphatase-like, alpha/beta/alpha; Alkaline-phosphatase-like, core domain; Protein of unknown function DUF229. Its molecular function is described by: catalytic activity. It is involved in the biological process described with: metabolic process; multicellular organism reproduction. 4 alleles are reported. The phenotype of these alleles manifest in: male accessory gland secondary cell. The phenotypic classes of alleles include: viable; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0000565	Eip71CD	-0.871076413	0.025478562	0.999936032	NA	MSRA	high	NA	NA	NA	"The gene Ecdysone-induced protein 28/29kD is referred to in FlyBase by the symbol Dmel\Eip71CD (CG7266, FBgn0000565). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (all unique). Gene sequence location is 3L:15511052..15513202. It has the cytological map location 71D3-71D4. Protein features are: Peptide methionine sulphoxide reductase MsrA. Its molecular function is described by: peptide-methionine (S)-S-oxide reductase activity. It is involved in the biological process described with: sulfur amino acid metabolic process; response to oxidative stress; oxidation-reduction process; determination of adult lifespan; autophagic cell death; neuron projection morphogenesis; salivary gland cell autophagic cell death; cellular response to oxidative stress. 13 alleles are reported. The phenotype of these alleles manifest in: eye. The phenotypic classes of alleles include: viable; phenotype; cell number defective; long lived; immune response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0030196	Psf3	-0.866094963	0.03396812	0.999936032	GINS3	GINS3	high	NA	NA	NA	"The gene Psf3 is referred to in FlyBase by the symbol Dmel\Psf3 (CG2222, FBgn0030196). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is X:10383353..10385861. It has the cytological map location 9B14. Protein features are: GINS complex, subunit Psf3; GINS subunit, domain A. Its molecular function is described by: 3'-5' DNA helicase activity. It is involved in the biological process described with: lateral inhibition. 4 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; embryonic/larval neuroblast; ganglion mother cell; chaeta. The phenotypic classes of alleles include: neuroanatomy defective; visible; viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0035781	CG8560	-0.860880817	0.026042412	0.999936032	NA	CPA2;CPA5;CPA4;CPA1;CPB1;CPO;CPA3;CPB2;CPA6	moderate;moderate;moderate;moderate;moderate;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8560 (FBgn0035781). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:7402332..7404181. It has the cytological map location 65F11. Protein features are: Carboxypeptidase, activation peptide; Insect gut carboxypeptidase-like, carboxypeptidase domain; Peptidase M14, carboxypeptidase A; Protease propeptides/proteinase inhibitor I9. Its molecular function is described by: metallocarboxypeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed at stages throughout the larval period, during early pupal stages.  "
FBgn0262843	CG43207	-0.858611078	0.037000163	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG43207 (FBgn0262843). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:23152748..23153318. It has the cytological map location 59D1. Its molecular function is described by: . It is involved in the biological process described with: . One allele is reported. No phenotypic data is available. No phenotypic class data is available.
FBgn0034500	CG11200	-0.857271784	0.029966427	0.999936032	DHRSX	DHRSX;RDH12;RDH11;DHRS13;RDH14;RDH13	high;low;low;low;low;low	NA	transmembrane protein	NA	"The gene Carbonyl reductase is referred to in FlyBase by the symbol Dmel\CG11200 (FBgn0034500). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:20304517..20308671. It has the cytological map location 56F16. Protein features are: NAD(P)-binding domain; Short-chain dehydrogenase/reductase SDR. Its molecular function is described by: oxidoreductase activity. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 06-18 hour embryonic stages, during early larval stages.  "
FBgn0033760	CG8785	-0.853490424	0.027730719	0.999936032	NA	SLC36A3;SLC36A2;SLC36A1;SLC36A4	moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8785 (FBgn0033760). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:12640690..12648224. It has the cytological map location 49B10-49B11. Protein features are: Amino acid transporter, transmembrane domain. Its molecular function is described by: amino acid transmembrane transporter activity. It is involved in the biological process described with: amino acid transmembrane transport. 5 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the pupal period.  "
FBgn0002578	Kaz-m1	-0.848339303	0.029058269	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Kazal-type protease inhibitor m1 is referred to in FlyBase by the symbol Dmel\Kaz-m1 (CG8342, FBgn0002578). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:26014721..26016487. It has the cytological map location 96F10. Protein features are: Kazal domain. Its molecular function is described by: serine-type endopeptidase inhibitor activity. It is involved in the biological process described with: regulation of proteolysis. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0038136	CG8774	-0.843349014	0.029437205	0.999936032	ENPEP	ENPEP;ANPEP;TRHDE;LVRN;LNPEP;ERAP1;ERAP2;NPEPPS	high;moderate;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8774 (FBgn0038136). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:13298768..13302334. It has the cytological map location 87E4-87E5. Protein features are: Aminopeptidase A; Aminopeptidase N-type; ERAP1-like C-terminal domain; Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase; Peptidase M1, membrane alanine aminopeptidase, N-terminal. Its molecular function is described by: peptide binding; metalloaminopeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis; peptide catabolic process; angiotensin maturation. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0034706	CG11275	-0.841844293	0.032274106	0.999936032	NA	KBTBD4;SPOPL;KLHL11;SPOP	low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11275 (FBgn0034706). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:22179695..22182642. It has the cytological map location 58C5. Protein features are: BTB/POZ domain; SKP1/BTB/POZ domain. Its molecular function is described by: ubiquitin protein ligase binding. It is involved in the biological process described with: protein ubiquitination involved in ubiquitin-dependent protein catabolic process; proteasome-mediated ubiquitin-dependent protein catabolic process; regulation of proteolysis. 4 alleles are reported. The phenotypes of these alleles manifest in: lipid particle; embryonic/larval fat body. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0033443	CG1698	-0.839722821	0.032511981	0.999936032	NA	SLC6A5;SLC6A11	moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1698 (FBgn0033443). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:9793326..9798006. It has the cytological map location 46B3. Protein features are: Sodium:neurotransmitter symporter. Its molecular function is described by: neurotransmitter:sodium symporter activity; cation:amino acid symporter activity; neurotransmitter transporter activity; transporter activity. It is involved in the biological process described with: transport; amino acid transmembrane import; neurotransmitter transport. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-18 embryonic stages, at stages throughout the pupal period.  "
FBgn0260874	Ir76a	-0.839139557	0.04249381	0.999936032	NA	GRID2	high	NA	transmembrane protein	NA	"The gene Ionotropic receptor 76a is referred to in FlyBase by the symbol Dmel\Ir76a (CG42584, FBgn0260874). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 3L:19799278..19803427. It has the cytological map location 76C6. Its molecular function is described by: ligand-gated ion channel activity; olfactory receptor activity. It is involved in the biological process described with: detection of chemical stimulus involved in sensory perception; transmission of nerve impulse; detection of chemical stimulus involved in sensory perception of smell. 10 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0264341	CG43797	-0.838679337	0.044842916	0.999936032	NA	FCER2;CLEC4E;CLEC4A;CLEC4G;CLEC17A;CLEC10A;CLEC4F;CD209;CLEC4C;CD207;CLEC4D;ASGR2;ASGR1;CLEC6A;CLEC4M	low;low;low;low;low;low;low;low;low;low;low;low;low;low;low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG43797 (FBgn0264341). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:4000018..4000806. It has the cytological map location 24D2. Protein features are: C-type lectin fold; C-type lectin-like; C-type lectin-like/link domain. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0031945	CG7191	-0.83832049	0.03581263	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7191 (FBgn0031945). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:7767628..7775033. It has the cytological map location 28C3. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; flight defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages.  "
FBgn0015033	Cyp4d8	-0.837235968	0.039022735	0.999936032	NA	CYP4V2;CYP26A1;CYP4A11;CYP4Z1;CYP4B1;CYP4F11;CYP4X1;CYP4F12;CYP4A22	moderate;high;low;low;low;low;low;low;low	NA	NA	NA	"The gene Cytochrome P450-4d8 is referred to in FlyBase by the symbol Dmel\Cyp4d8 (CG4321, FBgn0015033). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:7493557..7496179. It has the cytological map location 66A2. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Its molecular function is described by: iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; heme binding. It is involved in the biological process described with: oxidation-reduction process. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during late larval stages.  "
FBgn0040623	Spase12	-0.836401416	0.03421443	0.999936032	NA	SPCS1	high	NA	transmembrane protein	NA	"The gene Spase 12-subunit is referred to in FlyBase by the symbol Dmel\Spase12 (CG11500, FBgn0040623). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:29490544..29491150. It has the cytological map location 99B1. Protein features are: Microsomal signal peptidase 12kDa subunit. Its molecular function is described by: peptidase activity. It is involved in the biological process described with: protein targeting to ER; signal peptide processing. 5 alleles are reported. The phenotypes of these alleles manifest in: antenna; ommatidium; eye; leg; melanotic mass; interommatidial bristle. The phenotypic classes of alleles include: melanotic mass phenotype; lethal - all die during embryonic stage; planar polarity defective; visible. Summary of modENCODE Temporal Expression Profile:  No temporal expression data available due to processing error.  This will be corrected the next time these data and summaries are processed."
FBgn0039591	CG9988	-0.835207248	0.0465564	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9988 (FBgn0039591). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:28636411..28638799. It has the cytological map location 98D7. Protein features are: Alkaline phosphatase-like, alpha/beta/alpha; Alkaline-phosphatase-like, core domain; Protein of unknown function DUF229. Its molecular function is described by: catalytic activity. It is involved in the biological process described with: multicellular organism reproduction; metabolic process. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed at stages throughout the larval period.  "
FBgn0037818	CG6465	-0.829864652	0.039965164	0.999936032	ACY1	ACY1;ABHD14A;ABHD14A-ACY1;PM20D1	high;moderate;moderate;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6465 (FBgn0037818). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:10675560..10677251. It has the cytological map location 86C4. Protein features are: ArgE/DapE/ACY1/CPG2/YscS, conserved site; N-acyl-L-amino-acid amidohydrolase; Peptidase M20; Peptidase M20, dimerisation domain. Its molecular function is described by: aminoacylase activity; metallopeptidase activity. It is involved in the biological process described with: cellular amino acid metabolic process; proteolysis. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages.  "
FBgn0039298	to	-0.826262395	0.031861612	0.999936032	NA	NA	NA	NA	NA	NA	"The gene takeout is referred to in FlyBase by the symbol Dmel\to (CG11853, FBgn0039298). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:25240180..25241668. It has the cytological map location 96C7. Protein features are: Haemolymph juvenile hormone binding. Its molecular function is described by: . It is involved in the biological process described with: rhythmic behavior; male courtship behavior; feeding behavior; behavioral response to starvation; circadian rhythm; mating behavior; adult feeding behavior; response to starvation. 12 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: feeding behavior defective; viable; fertile; circadian rhythm defective; partially lethal - majority live. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed in adult male stages.  "
FBgn0040805	CG12355	-0.823304081	0.0354972	0.999936032	MPV17L	MPV17L	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12355 (FBgn0040805). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3L:15492964..15495549. It has the cytological map location 71D3. Protein features are: Mpv17/PMP22. Its molecular function is described by: . It is involved in the biological process described with: . 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, in adult male stages.  "
FBgn0038416	CG17930	-0.821825599	0.034420731	0.999936032	NA	SLC2A12;SLC2A13;SLC2A8;SLC2A6;SLC2A10	low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17930 (FBgn0038416). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:16327849..16329622. It has the cytological map location 89B12. Protein features are: Major facilitator superfamily domain; Major facilitator,  sugar transporter-like. Its molecular function is described by: transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; flight defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0038846	CG5697	-0.821106431	0.050301107	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5697 (FBgn0038846). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 3R:21015949..21017120. It has the cytological map location 93B4. Protein features are: Solute carrier family 3 member 2, N-terminal domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; some die during pupal stage; short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed during early pupal stages.  "
FBgn0039045	CG17119	-0.817646567	0.035335069	0.999936032	CTNS	CTNS	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17119 (FBgn0039045). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:23054410..23058958. It has the cytological map location 94D10. Protein features are: Lysosomal cystine transporter; PQ-loop repeat; TonB box, conserved site. Its molecular function is described by: amino acid transmembrane transporter activity; L-cystine transmembrane transporter activity. It is involved in the biological process described with: L-cystine transport; amino acid transmembrane transport. 8 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0034197	Cda9	-0.817485483	0.037089434	0.999936032	NA	CHIA;OVGP1;CHI3L2;CHI3L1	low;low;low;low	NA	NA	NA	"The gene Chitin deacetylase-like 9 is referred to in FlyBase by the symbol Dmel\Cda9 (CG15918, FBgn0034197). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:17128480..17130334. It has the cytological map location 53F13. Protein features are: Glycoside hydrolase/deacetylase, beta/alpha-barrel; NodB homology domain. Its molecular function is described by: chitin binding; chitinase activity; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds. It is involved in the biological process described with: chitin catabolic process; carbohydrate metabolic process. One allele is reported. No phenotypic data is available. The phenotypic classes of allele include: partially lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the larval period.  "
FBgn0031089	CG9572	-0.814824579	0.046849854	0.999936032	NA	CHN1;CHN2;LTBP1;DLL4;VWCE;CRB2;LOC100996717;DLK2;VWA1;CFC1B;SCUBE2;JAG2;F12;SCUBE3;HABP2;COL14A1;CFC1;NOTCH2NL;EYS;COL22A1;DLL3;JAG1;EGFL7;MATN3;HGFAC;FBLN7;SVEP1;SNED1;TDGF1;DLK1	low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9572 (FBgn0031089). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is X:20148124..20155514. It has the cytological map location 19B3. Protein features are: EGF-like domain; EGF-like, conserved site. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0032713	CG17323	-0.814528213	0.052386189	0.999936032	NA	UGT1A3;UGT2B10;UGT1A1;UGT3A1;UGT8;UGT2B4;UGT2B15;UGT2B28;UGT2A2;UGT3A2;UGT2B17;UGT2B11;UGT2A3;UGT2B7	moderate;moderate;low;low;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17323 (FBgn0032713). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2L:18823548..18826716. It has the cytological map location 37B1. Protein features are: UDP-glucuronosyl/UDP-glucosyltransferase; UDP-glycosyltransferase family, conserved site. Its molecular function is described by: glucuronosyltransferase activity. It is involved in the biological process described with: inter-male aggressive behavior; metabolic process. 11 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 06-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0036381	CG8745	-0.813534324	0.034591493	0.999936032	ETNPPL	ETNPPL;PHYKPL	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8745 (FBgn0036381). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:13860027..13866905. It has the cytological map location 70C5. Protein features are: Aminotransferase class-III; Pyridoxal phosphate-dependent transferase; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; Pyridoxal phosphate-dependent transferase, subdomain 2. Its molecular function is described by: pyridoxal phosphate binding; alanine-glyoxylate transaminase activity; identical protein binding. It is involved in the biological process described with: arginine catabolic process to glutamate; response to nicotine. 8 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 06-18 hour embryonic stages, at stages throughout the larval period, during early pupal stages.  "
FBgn0259834	out	-0.809252693	0.037048928	0.999936032	NA	SLC16A11;SLC16A12;SLC16A6;SLC16A1	moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene outsiders is referred to in FlyBase by the symbol Dmel\out (CG8062, FBgn0259834). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:19310513..19322106. It has the cytological map location 18C2. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain. Its molecular function is described by: monocarboxylic acid transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; ectopic germ cell programmed cell death; germ cell development. 24 alleles are reported. The phenotypes of these alleles manifest in: wing; germline cell; pole cell; embryonic/larval hemocyte. The phenotypic classes of alleles include: some die during pupal stage; lethal - all die before end of pupal stage; viable; visible; fertile; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0031998	SLC5A11	-0.809153106	0.04300333	0.999936032	NA	SLC5A5;SLC5A8;SLC5A6;SLC5A12	moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene Sodium/solute co-transporter-like 5A11 is referred to in FlyBase by the symbol Dmel\SLC5A11 (CG8451, FBgn0031998). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:8200465..8205132. It has the cytological map location 28F1. Protein features are: Sodium/solute symporter. Its molecular function is described by: transporter activity. It is involved in the biological process described with: transmembrane transport; adult feeding behavior; behavioral response to nutrient. 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: short lived; viable; feeding behavior defective; chemical resistant. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed in adult male stages.  "
FBgn0038803	CG5191	-0.807935614	0.048751279	0.999936032	NA	FAAH2;FAAH	moderate;low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG5191 (FBgn0038803). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (3 unique). Gene sequence location is 3R:20560865..20573000. It has the cytological map location 92F1-92F2. Protein features are: Amidase signature domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 11 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 12-18 embryonic stages.
FBgn0041629	Hexo2	-0.805644368	0.054580022	0.999936032	NA	HEXA;HEXB	moderate;moderate	NA	transmembrane protein	NA	"The gene Hexosaminidase 2 is referred to in FlyBase by the symbol Dmel\Hexo2 (CG1787, FBgn0041629). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:8709652..8712478. It has the cytological map location 8A2. Protein features are: Beta-hexosaminidase; Beta-hexosaminidase, eukaryotic type, N-terminal; Chitobiase/beta-hexosaminidase domain 2-like; Glycoside hydrolase family 20, catalytic domain; Glycoside hydrolase superfamily. Its molecular function is described by: beta-N-acetylglucosaminidase activity. It is involved in the biological process described with: negative regulation of growth of symbiont in host; carbohydrate metabolic process; multicellular organism reproduction. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0031248	CG11912	-0.804394756	0.037134727	0.999936032	NA	CTRB2;CTRB1;PRSS38;CTRL;AZU1;PRTN3	low;low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11912 (FBgn0031248). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:318362..319259. It has the cytological map location 21B8. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of no expression detected.  Peak expression observed during late larval stages.  "
FBgn0261439	SdhA	-0.798533497	0.037289184	0.999936032	NA	SDHA	high	NA	NA	NA	"The gene Succinate dehydrogenase, subunit A (flavoprotein) is referred to in FlyBase by the symbol Dmel\SdhA (CG17246, FBgn0261439). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:19391863..19395971. It has the cytological map location 56D3. Protein features are: FAD-dependent oxidoreductase 2, FAD binding domain; FAD/NAD(P)-binding domain; Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal; Fumarate reductase/succinate dehydrogenase, FAD-binding site; Succinate dehydrogenase, flavoprotein subunit; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. Its molecular function is described by: electron carrier activity; succinate dehydrogenase (ubiquinone) activity; flavin adenine dinucleotide binding. It is involved in the biological process described with: electron transport chain; anaerobic respiration; tricarboxylic acid cycle; mitochondrial electron transport, succinate to ubiquinone. 18 alleles are reported. The phenotypes of these alleles manifest in: eye photoreceptor cell; rhabdomere; retina; ommatidium; ovariole. The phenotypic classes of alleles include: viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 06-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0030485	CG1998	-0.795545099	0.047620572	0.999936032	FAXDC2	FAXDC2;MSMO1	high;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1998 (FBgn0030485). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:13409369..13413074. It has the cytological map location 11F4. Protein features are: Fatty acid hydroxylase. Its molecular function is described by: oxidoreductase activity; iron ion binding. It is involved in the biological process described with: oxidation-reduction process; lipid biosynthetic process; lipid metabolic process. 12 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed during early pupal stages, in adult male stages.  "
FBgn0035480	CG14984	-0.794983379	0.058414399	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14984 (FBgn0035480). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:3951193..3952550. It has the cytological map location 64A1. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during early pupal stages, in adult male stages.  "
FBgn0039114	Lsd-1	-0.794228605	0.050951136	0.999936032	NA	PLIN3;PLIN1;PLIN5;PLIN2	high;moderate;moderate;low	NA	NA	NA	"The gene Lipid storage droplet-1 is referred to in FlyBase by the symbol Dmel\Lsd-1 (CG10374, FBgn0039114). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 3R:23763857..23766662. It has the cytological map location 95B1. Protein features are: Perilipin. Its molecular function is unknown. It is involved in the biological process described with: positive regulation of triglyceride catabolic process; lipid particle organization; lipid transport; triglyceride mobilization; lipid storage; regulation of lipid storage; protein localization to lipid particle. 21 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval fat body; mesothoracic tergum; mitochondrion; wing; wing pouch; lipid particle; ganglion mother cell. The phenotypic classes of alleles include: stress response defective; some die during P-stage; phenotype; size defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0029843	Nep1	-0.793923122	0.043863396	0.999936032	NA	MMEL1;MME;ECE2;PHEX;ECE1;ECEL1	high;moderate;moderate;moderate;low;low	NA	transmembrane protein	NA	"The gene Neprilysin 1 is referred to in FlyBase by the symbol Dmel\Nep1 (CG5905, FBgn0029843). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is X:6091205..6103971. It has the cytological map location 5D4-5D5. Protein features are: Metallopeptidase, catalytic domain; Neprilysin-21; Peptidase M13; Peptidase M13, C-terminal domain; Peptidase M13, N-terminal domain. Its molecular function is described by: metallopeptidase activity; metalloendopeptidase activity. It is involved in the biological process described with: proteolysis. 11 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: visible; female semi-sterile; viable; lethal; male semi-sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0032405	firl	-0.79303001	0.059115264	0.999936032	NA	HSD17B11;HSD17B13;DHRS3;SDR16C5;RDH10	moderate;low;low;low;low	NA	NA	NA	"The gene firelighter is referred to in FlyBase by the symbol Dmel\firl (CG14946, FBgn0032405). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:12063457..12066775. It has the cytological map location 33C2. Protein features are: NAD(P)-binding domain; Short-chain dehydrogenase/reductase SDR; Short-chain dehydrogenase/reductase, conserved site. Its molecular function is described by: oxidoreductase activity. It is involved in the biological process described with: detection of temperature stimulus involved in sensory perception of pain. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; heat stress response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during early pupal stages.  "
FBgn0264863	CR44054	-0.788170211	0.037277936	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44054 (FBgn0264863). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is X:11139608..11141238. It has the cytological map location 10A7. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available.
FBgn0032706	Irk3	-0.787998127	0.06071709	0.999936032	NA	KCNJ15;KCNJ10;KCNJ9;KCNJ12;KCNJ2;KCNJ8;KCNJ1;KCNJ18;KCNJ14;KCNJ4;KCNJ11;KCNJ3;KCNJ16;KCNJ13;KCNJ6;KCNJ5	moderate;moderate;moderate;low;low;low;low;low;low;low;low;low;low;moderate;low;low	NA	transmembrane protein	NA	"The gene Inwardly rectifying potassium channel 3 is referred to in FlyBase by the symbol Dmel\Irk3 (CG10369, FBgn0032706). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 2L:18711071..18713748. It has the cytological map location 37A1. Protein features are: Immunoglobulin E-set; Potassium channel, inwardly rectifying, Kir; Potassium channel, inwardly rectifying, Kir, cytoplasmic. Its molecular function is described by: inward rectifier potassium channel activity. It is involved in the biological process described with: wing disc development; regulation of membrane potential; potassium ion transport; potassium ion import. 5 alleles are reported. The phenotypes of these alleles manifest in: wing hinge; wing; wing vein. The phenotypic classes of alleles include: size defective; increased mortality; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 06-12 hour embryonic stages, during early larval stages, in stages of adults of both sexes.  "
FBgn0011576	Cyp4d2	-0.787873177	0.050121794	0.999936032	NA	CYP4V2;CYP4A11;CYP4Z1;CYP4B1;CYP4F11;CYP4X1;CYP4F12;CYP4A22;CYP4F2;CYP4F8;CYP4F3;CYP4F22	moderate;low;low;low;moderate;low;low;low;moderate;moderate;low;moderate	NA	transmembrane protein	NA	"The gene Cytochrome P450-4d2 is referred to in FlyBase by the symbol Dmel\Cyp4d2 (CG3466, FBgn0011576). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:2176006..2178728. It has the cytological map location 2E1. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Its molecular function is described by: heme binding; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. It is involved in the biological process described with: oxidation-reduction process. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die during P-stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed during late larval stages, in adult male stages.  "
FBgn0036787	CG4306	-0.784776222	0.033857338	0.999936032	GGCT	GGCT	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG4306 (FBgn0036787). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:18461957..18463163. It has the cytological map location 75C7. Protein features are: Gamma-glutamyl cyclotransferase-like; Gamma-glutamylcyclotransferase. Its molecular function is described by: gamma-glutamylcyclotransferase activity. It is involved in the biological process described with: hemolymph coagulation. 5 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 06-18 hour embryonic stages.
FBgn0026077	Gasp	-0.778885856	0.055027211	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Gasp is referred to in FlyBase by the symbol Dmel\Gasp (CG10287, FBgn0026077). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:6088799..6100887. It has the cytological map location 83D4. Protein features are: Chitin binding domain. Its molecular function is described by: chitin binding. It is involved in the biological process described with: chitin metabolic process; chitin-based embryonic cuticle biosynthetic process; regulation of multicellular organism growth; regulation of tube size, open tracheal system. 12 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval trachea; embryonic/larval dorsal trunk. The phenotypic classes of alleles include: viable; small body. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period.  "
FBgn0030331	CG15221	-0.778035985	0.063680326	0.999936032	NA	SV2C;SV2A	moderate;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15221 (FBgn0030331). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:11724246..11736617. It has the cytological map location 10D8-10E1. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain. Its molecular function is described by: substrate-specific transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die during embryonic stage; lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0036040	CG6749	-0.77780632	0.063345453	0.999936032	NA	CPN2;IGFALS;TRIL;CHAD;CHADL	low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6749 (FBgn0036040). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:9731238..9733807. It has the cytological map location 67C5-67C6. Protein features are: Leucine-rich repeat; Leucine-rich repeat domain, L domain-like; Leucine-rich repeat, typical subtype. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed during early pupal stages.  "
FBgn0003714	tko	-0.777330753	0.046056159	0.999936032	MRPS12	MRPS12	high	NA	NA	NA	"The gene technical knockout is referred to in FlyBase by the symbol Dmel\tko (CG7925, FBgn0003714). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:2442313..2443976. It has the cytological map location 3A3. Protein features are: Nucleic acid-binding, OB-fold; Ribosomal protein S12, bacterial-type; Ribosomal protein S12/S23. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: translation; response to mechanical stimulus; male courtship behavior; response to hypoxia; mechanosensory behavior; sensory perception of sound; courtship behavior; mitochondrial translation. 24 alleles are reported. The phenotypes of these alleles manifest in: egg; adult antennal lobe projection neuron DL1 adPN; gamma Kenyon cell; mitochondrion; macrochaeta. The phenotypic classes of alleles include: increased mortality during development; viable; mating defective; phenotype; lethal - all die before end of larval stage; chemical sensitive; wild-type; sterile; neuroanatomy defective; auditory perception defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in adult female stages.  "
FBgn0033981	Cyp6a21	-0.775598567	0.045934118	0.999936032	TBXAS1	TBXAS1;CYP3A43;CYP3A4;CYP3A5;CYP3A7-CYP3A51P;CYP3A7	moderate;moderate;moderate;moderate;low;low	NA	NA	NA	"The gene Cyp6a21 is referred to in FlyBase by the symbol Dmel\Cyp6a21 (CG10247, FBgn0033981). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:14885264..14886947. It has the cytological map location 51D1. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Its molecular function is described by: oxidoreductase activity; heme binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; iron ion binding. It is involved in the biological process described with: oxidation-reduction process. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period.  "
FBgn0030051	spirit	-0.775401381	0.058176081	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene Serine Protease Immune Response Integrator is referred to in FlyBase by the symbol Dmel\spirit (CG2056, FBgn0030051). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is X:8571099..8573593. It has the cytological map location 7F5. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Proteinase, regulatory CLIP domain; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: positive regulation of Toll signaling pathway; defense response to Gram-negative bacterium; proteolysis; defense response to fungus; defense response to Gram-positive bacterium; innate immune response. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: immune response defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0033782	sug	-0.773375229	0.044752957	0.999936032	NA	GLIS2	high	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene sugarbabe is referred to in FlyBase by the symbol Dmel\sug (CG3850, FBgn0033782). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:12924567..12930644. It has the cytological map location 49E1. Protein features are: Zinc finger C2H2-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: nucleic acid binding. It is involved in the biological process described with: negative regulation of transcription from RNA polymerase II promoter; insulin-like growth factor receptor signaling pathway; cellular response to nutrient; negative regulation of transcription, DNA-templated; positive regulation of transcription, DNA-templated; response to starvation. 10 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: developmental rate defective; starvation stress response defective; lethal; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, in adult male stages.  "
FBgn0052379	CG32379	-0.772559952	0.063986772	0.999936032	NA	CPA2;CPA5;CPA1;CPA4;CPO;CPA3;CPB2;CPB1;CPA6	moderate;moderate;moderate;moderate;low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32379 (FBgn0052379). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:7396355..7398208. It has the cytological map location 65F11. Protein features are: Insect gut carboxypeptidase-like, carboxypeptidase domain; Peptidase M14, carboxypeptidase A. Its molecular function is described by: zinc ion binding; metallocarboxypeptidase activity. It is involved in the biological process described with: proteolysis. 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely low expression to a trough of no expression detected.  Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in adult male stages.  "
FBgn0033448	hebe	-0.772176091	0.041826539	0.999936032	NA	NA	NA	NA	NA	NA	"The gene hebe is referred to in FlyBase by the symbol Dmel\hebe (CG1623, FBgn0033448). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2R:9828104..9836642. It has the cytological map location 46B4. Its molecular function is unknown. It is involved in the biological process described with: determination of adult lifespan. 24 alleles are reported. The phenotypes of these alleles manifest in: Z disc; myofibril; sarcomere. The phenotypic classes of alleles include: long lived; flightless; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0037845	CG14694	-0.765153757	0.055404625	0.999936032	SLC19A3	SLC19A3;SLC19A1;SLC19A2;C2orf83	moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG14694 (FBgn0037845). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:10858202..10859813. It has the cytological map location 86C7. Protein features are: Major facilitator superfamily domain; Reduced folate carrier. Its molecular function is described by: transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed in adults stages of both sexes.
FBgn0032620	CG12288	-0.764498889	0.068922083	0.999936032	NA	RBM34	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12288 (FBgn0032620). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:16900535..16902218. It has the cytological map location 36B4. Protein features are: RBM34, RNA recognition motif 1; RNA recognition motif domain. Its molecular function is described by: nucleic acid binding; mRNA binding. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0263607	l(3)72Dp	-0.763928813	0.051249873	0.999936032	NA	GGH	high	NA	NA	NA	"The gene lethal (3) 72Dp is referred to in FlyBase by the symbol Dmel\l(3)72Dp (CG32155, FBgn0263607). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:16234140..16236999. It has the cytological map location 72D10. Protein features are: Class I glutamine amidotransferase-like; Peptidase C26; Peptidase C26, gamma-glutamyl hydrolase. Its molecular function is described by: gamma-glutamyl-peptidase activity. It is involved in the biological process described with: tetrahydrofolylpolyglutamate metabolic process. 11 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable; some die during embryonic stage; some die during pupal stage; partially lethal; lethal - all die before end of pupal stage."
FBgn0266448	CG45078	-0.762467066	0.051160461	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG45078 (FBgn0266448). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:10773339..10777374. It has the cytological map location 86C6. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available.
FBgn0085330	CG34301	-0.762319462	0.067313201	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG34301 (FBgn0085330). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:8773435..8773810. It has the cytological map location 85B1. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period.
FBgn0025336	CG4882	-0.762317329	0.052734394	0.999936032	NA	MRPS27	high	DNA-binding with transcription factor activity	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4882 (FBgn0025336). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:23880817..23882927. It has the cytological map location 60A7. Protein features are: 28S ribosomal protein S27, mitochondrial; MRPS27/PTCD2. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: lethal - all die during larval stage; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed during early larval stages.  "
FBgn0035780	CG18417	-0.761599752	0.046648953	0.999936032	NA	CPA2;CPA5;CPA4;CPA1;CPB1;CPO;CPA3;CPB2;CPA6	moderate;moderate;moderate;moderate;moderate;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG18417 (FBgn0035780). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:7400070..7401671. It has the cytological map location 65F11. Protein features are: Carboxypeptidase, activation peptide; Insect gut carboxypeptidase-like, carboxypeptidase domain; Peptidase M14, carboxypeptidase A; Protease propeptides/proteinase inhibitor I9. Its molecular function is described by: metallocarboxypeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis. 4 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; chaeta. The phenotypic classes of alleles include: body color defective; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed during late larval stages.  "
FBgn0037846	CG6574	-0.761383935	0.047711616	0.999936032	SLC19A3	SLC19A3;SLC19A2;SLC19A1;C2orf83	high;moderate;moderate;moderate	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG6574 (FBgn0037846). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:10860531..10862988. It has the cytological map location 86C7. Protein features are: Major facilitator superfamily domain; Reduced folate carrier. Its molecular function is described by: transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed during early pupal stages.
FBgn0035370	Non2	-0.759878935	0.050181488	0.999936032	NA	SMARCD3;SMARCD2;SMARCD1	low;low;low	NA	NA	NA	"The gene Novel nucleolar protein 2 is referred to in FlyBase by the symbol Dmel\Non2 (CG1240, FBgn0035370). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:2766999..2768392. It has the cytological map location 62F3. Protein features are: DEK, C-terminal; SWIB domain; SWIB/MDM2 domain. Its molecular function is described by: . It is involved in the biological process described with: mitotic spindle assembly. 4 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: lethal - all die during embryonic stage; lethal; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0039873	Smvt	-0.758494157	0.068285743	0.999936032	NA	SLC5A5;SLC5A8;SLC5A6;SLC5A12;SLC5A1	moderate;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene Sodium-dependent multivitamin transporter is referred to in FlyBase by the symbol Dmel\Smvt (CG2191, FBgn0039873). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:31759404..31761579. It has the cytological map location 100D2. Protein features are: Sodium/solute symporter. Its molecular function is described by: transporter activity. It is involved in the biological process described with: transmembrane transport. 6 alleles are reported. The phenotypes of these alleles manifest in: myofibril; sarcomere; Z disc; trichogen cell. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; flightless; fertile; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0036831	CG6839	-0.757060254	0.044468012	0.999936032	NA	ENDOG	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6839 (FBgn0036831). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:18917581..18919259. It has the cytological map location 75E5-75E6. Protein features are: DNA/RNA non-specific endonuclease; Extracellular Endonuclease, subunit A. Its molecular function is described by: nucleic acid binding; hydrolase activity; metal ion binding. It is involved in the biological process described with: apoptotic DNA fragmentation. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period.  "
FBgn0035571	CG12493	-0.756423363	0.061284138	0.999936032	NA	STAU1;STAU2;ADARB1;ADARB2	low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12493 (FBgn0035571). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:4752393..4753738. It has the cytological map location 64B16. Protein features are: Double-stranded RNA-binding domain. Its molecular function is described by: siRNA binding; double-stranded RNA binding. The biological processes in which it is involved are not known. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; male fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the pupal period, in adult male stages.  "
FBgn0260972	alc	-0.756095751	0.045828517	0.999936032	NA	PRKAB1;PRKAB2	high;high	NA	NA	NA	"The gene alicorn is referred to in FlyBase by the symbol Dmel\alc (CG8057, FBgn0260972). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:9135375..9137933. It has the cytological map location 45A9-45B1. Protein features are: 5'-AMP-activated protein kinase subunit beta-1; AMP-activated protein kinase, glycogen-binding domain; Association with the SNF1 complex (ASC) domain; Immunoglobulin E-set; Immunoglobulin-like fold. Its molecular function is unknown. It is involved in the biological process described with: neuron cellular homeostasis; signal transduction; regulation of protein kinase activity; cellular response to DNA damage stimulus; maintenance of apical/basal cell polarity. 14 alleles are reported. The phenotypes of these alleles manifest in: oocyte associated follicular epithelium; retina; antenna; embryo; optic lobe; eye photoreceptor cell. The phenotypic classes of alleles include: increased mortality; lethal; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0033391	CG8026	-0.754478632	0.047544856	0.999936032	NA	SLC25A32	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8026 (FBgn0033391). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 2R:9186670..9192096. It has the cytological map location 45B3. Protein features are: Mitochondrial carrier domain; Mitochondrial carrier protein; Mitochondrial substrate/solute carrier. Its molecular function is described by: FAD transmembrane transporter activity; folic acid transporter activity. It is involved in the biological process described with: transmembrane transport; folic acid transport; mitochondrial transport. 11 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, in adult female stages.  "
FBgn0030098	CG12057	-0.753922429	0.04483629	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG12057 (FBgn0030098). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:9191657..9192548. It has the cytological map location 8C17. Protein features are: Protein of unknown function DUF725. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of extremely low expression.  Peak expression observed during late larval stages.
FBgn0003475	spir	-0.75375712	0.055190477	0.999936032	NA	SPIRE1;SPIRE2	high;moderate	NA	NA	NA	"The gene spire is referred to in FlyBase by the symbol Dmel\spir (CG10076, FBgn0003475). It is a protein_coding_gene from Drosophila melanogaster. It has 10 annotated transcripts and 10 polypeptides (9 unique). Gene sequence location is 2L:20311219..20348386. It has the cytological map location 38C5. Protein features are: KIND domain; Protein Spire; WH2 domain; Zinc finger, FYVE/PHD-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: protein binding; microtubule binding; actin binding. It is involved in the biological process described with 13 unique terms, many of which group under: regulation of actin filament-based process; transport; vesicle-mediated transport; actin filament network formation; positive regulation of protein polymerization; regulation of cytoskeleton organization; establishment of localization; positive regulation of biological process; cellular macromolecule localization; ovarian follicle cell development. 71 alleles are reported. The phenotypes of these alleles manifest in: material anatomical entity; embryo; oocyte nucleus; cell component; acellular anatomical structure; cell periphery; epithelial cell; embryonic abdomen; dorsal closure embryo; chorion. The phenotypic classes of alleles include: increased mortality during development; phenotype; increased mortality; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0033913	CG8468	-0.753231805	0.057470847	0.999936032	NA	SLC16A14;SLC16A11;SLC16A9	moderate;low;low	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG8468 (FBgn0033913). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:14219898..14230620. It has the cytological map location 50E4. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain. Its molecular function is described by: monocarboxylic acid transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; monocarboxylic acid transport. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages.
FBgn0034145	CG5065	-0.747922012	0.050877112	0.999936032	FAR2	FAR2;FAR1	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5065 (FBgn0034145). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is 2R:16607654..16624894. It has the cytological map location 53C11-53C12. Protein features are: Fatty acyl-CoA reductase; Fatty acyl-CoA reductase, C-terminal; Male sterility, NAD-binding; NAD(P)-binding domain. Its molecular function is described by: long-chain-fatty-acyl-CoA reductase activity; fatty-acyl-CoA reductase (alcohol-forming) activity. It is involved in the biological process described with: ether lipid biosynthetic process; long-chain fatty-acyl-CoA metabolic process; wax biosynthetic process. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal - all die before end of pupal stage; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages, in adult male stages.  "
FBgn0260000	CG17570	-0.747513951	0.058681211	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG17570 (FBgn0260000). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:20263419..20264424. It has the cytological map location 38C3. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages.
FBgn0003062	Fib	-0.747353157	0.060345894	0.999936032	FBL	FBL;FBLL1	high;moderate	NA	NA	NA	"The gene Fibrillarin is referred to in FlyBase by the symbol Dmel\Fib (CG9888, FBgn0003062). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:23072909..23074725. It has the cytological map location 59C3. Protein features are: Fibrillarin; Fibrillarin, conserved site; S-adenosyl-L-methionine-dependent methyltransferase. Its molecular function is described by: rRNA methyltransferase activity; histone-glutamine methyltransferase activity; RNA binding. It is involved in the biological process described with: rRNA methylation; box C/D snoRNA 3'-end processing; cellular response to starvation; histone glutamine methylation; tRNA processing. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: female sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0034711	Alp2	-0.745182051	0.048708526	0.999936032	NA	ALPPL2;ALPI;ALPP;ALPL	moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	NA
FBgn0027091	CysRS	-0.743687586	0.06015535	0.999936032	NA	CARS;CARS2	high;low	NA	NA	NA	"The gene Cysteinyl-tRNA synthetase is referred to in FlyBase by the symbol Dmel\CysRS (CG8431, FBgn0027091). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:16143147..16145906. It has the cytological map location 52E11. Protein features are: Aminoacyl-tRNA synthetase, class Ia, anticodon-binding; Cysteine-tRNA ligase; Cysteinyl-tRNA synthetase/mycothiol ligase; Rossmann-like alpha/beta/alpha sandwich fold; tRNA synthetases class I, catalytic domain. Its molecular function is described by: ATP binding; tRNA binding; cysteine-tRNA ligase activity. It is involved in the biological process described with: cysteinyl-tRNA aminoacylation. 5 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: lethal; visible; viable; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0260388	CG42514	-0.7413754	0.060434927	0.999936032	NA	SLC46A3;SLC46A1;SLC46A2	moderate;high;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG42514 (FBgn0260388). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:16491838..16496236. It has the cytological map location 73A3. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain. Its molecular function is described by: adenylate cyclase activity. It is involved in the biological process described with: transmembrane transport. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; short lived; viable; flight defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0033130	Tsp42Ei	-0.741056931	0.074921911	0.999936032	NA	TSPAN3;PRPH2	low;low	NA	transmembrane protein	NA	"The gene Tetraspanin 42Ei is referred to in FlyBase by the symbol Dmel\Tsp42Ei (CG12843, FBgn0033130). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:7035125..7036949. It has the cytological map location 42E5. Protein features are: Tetraspanin; Tetraspanin, EC2 domain; Tetraspanin/Peripherin. Its molecular function is described by: . It is involved in the biological process described with: cell surface receptor signaling pathway. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0035907	GstO1	-0.741007962	0.07105535	0.999936032	GSTO1	GSTO1;GSTO2	moderate;moderate	NA	NA	NA	"The gene Glutathione S transferase O1 is referred to in FlyBase by the symbol Dmel\GstO1 (CG6662, FBgn0035907). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:8523742..8524866. It has the cytological map location 66D5. Protein features are: Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Glutathione S-transferase, omega-class; Thioredoxin-like fold. Its molecular function is described by: glutathione transferase activity; transferase activity, transferring sulfur-containing groups; glutathione dehydrogenase (ascorbate) activity. It is involved in the biological process described with: toxin catabolic process; glutathione metabolic process. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0000055	Adh	-0.738995678	0.048994301	0.999936032	NA	HPGD	moderate	NA	NA	NA	"The gene Alcohol dehydrogenase is referred to in FlyBase by the symbol Dmel\Adh (CG3481, FBgn0000055). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is 2L:14615552..14618902. It has the cytological map location 35B3. Protein features are: Alcohol dehydrogenase, Drosophila-type; Alcohol dehydrogenase, insect-type; NAD(P)-binding domain; Short-chain dehydrogenase/reductase SDR; Short-chain dehydrogenase/reductase, conserved site. Its molecular function is described by: protein homodimerization activity; acetaldehyde dehydrogenase (acetylating) activity; alcohol dehydrogenase (NAD) activity. It is involved in the biological process described with: acetaldehyde metabolic process; alcohol metabolic process; ethanol oxidation; ethanol metabolic process; alcohol catabolic process; behavioral response to ethanol. 491 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: electrophoretic variant; locomotor behavior defective; chemical sensitive; wild-type; chemical resistant. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of low expression.  Peak expression observed at stages throughout the larval period, in adult male stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0033733	CG8834	-0.734013912	0.049983303	0.999936032	NA	ACSBG1;SLC27A6;ACSF3	low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8834 (FBgn0033733). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:12420475..12422535. It has the cytological map location 49A4. Protein features are: AMP-binding enzyme, C-terminal domain; AMP-binding, conserved site; AMP-dependent synthetase/ligase. Its molecular function is described by: catalytic activity. It is involved in the biological process described with: metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed in adults stages of both sexes.  "
FBgn0037485	CG14606	-0.733677908	0.073242412	0.999936032	NA	SLC2A8;SLC2A6	moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14606 (FBgn0037485). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:7214339..7217083. It has the cytological map location 84D2. Protein features are: Major facilitator superfamily domain; Major facilitator,  sugar transporter-like; Sugar transporter, conserved site. Its molecular function is described by: glucose transmembrane transporter activity; sugar:proton symporter activity. It is involved in the biological process described with: hexose transmembrane transport; phagocytosis; glucose import. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed during early larval stages, in adult male stages.  "
FBgn0023541	Cyp4d14	-0.733576121	0.056629479	0.999936032	NA	CYP4V2;CYP4A11;CYP4Z1;CYP4B1;CYP4F11;CYP4X1;CYP4F12;CYP4A22;CYP4F8;CYP46A1;CYP4F3;CYP4F2;CYP4F22	moderate;low;low;low;moderate;low;low;low;moderate;moderate;low;low;moderate	NA	NA	NA	"The gene Cyp4d14 is referred to in FlyBase by the symbol Dmel\Cyp4d14 (CG3540, FBgn0023541). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:2173415..2175315. It has the cytological map location 2E1. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Its molecular function is described by: heme binding; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. It is involved in the biological process described with: oxidation-reduction process. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0028480	CG17841	-0.73318272	0.051555999	0.999936032	NA	FAM57B;FAM57A	high;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17841 (FBgn0028480). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:10368052..10383580. It has the cytological map location 9B12-9B14. Protein features are: TRAM/LAG1/CLN8 homology domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal; fertile; lethal - all die before end of pupal stage; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 12-24 hour embryonic stages, in adult male stages.  "
FBgn0031887	CG11289	-0.731885548	0.05656065	0.999936032	NA	UGT1A3;UGT2B10;UGT1A1;UGT3A1;UGT8;UGT2B4;UGT2B15;UGT2B28;UGT2A2;UGT3A2;UGT2B17;UGT2B11;UGT2A3;UGT2B7	moderate;moderate;low;low;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11289 (FBgn0031887). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:7067983..7069546. It has the cytological map location 27D7-27E1. Protein features are: UDP-glucuronosyl/UDP-glucosyltransferase. Its molecular function is described by: transferase activity, transferring hexosyl groups; UDP-glycosyltransferase activity. It is involved in the biological process described with: metabolic process. 3 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages.  "
FBgn0050381	PIG-X	-0.730928619	0.064551287	0.999936032	NA	PIGX	high	NA	transmembrane protein	NA	"The gene Phosphatidylinositol glycan anchor biosynthesis class X is referred to in FlyBase by the symbol Dmel\PIG-X (CG30381, FBgn0050381). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:7929658..7931016. It has the cytological map location 43F2. Protein features are: Glycosylphosphatidylinositol-mannosyltransferase I, PIG-X/PBN1. Its molecular function is described by: . It is involved in the biological process described with: GPI anchor biosynthetic process. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0028886	CG15279	-0.73084338	0.075594618	0.999936032	NA	SLC6A5	moderate	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG15279 (FBgn0028886). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:14844993..14851749. It has the cytological map location 35B6. Protein features are: Sodium:neurotransmitter symporter. Its molecular function is described by: neurotransmitter:sodium symporter activity; cation:amino acid symporter activity; neurotransmitter transporter activity; transporter activity. It is involved in the biological process described with: transport; amino acid transmembrane import; neurotransmitter transport. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during late larval stages.
FBgn0032753	CG17572	-0.728727559	0.076540578	0.999936032	NA	PRSS8	low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17572 (FBgn0032753). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:19071131..19074149. It has the cytological map location 37B13. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site. Its molecular function is unknown. It is involved in the biological process described with: proteolysis. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-18 embryonic stages, in adult male stages.  "
FBgn0036415	CG7768	-0.727709978	0.083313221	0.999936032	PPIF	PPIF;PPIA;PPIAL4G;PPIAL4C;PPIAL4D;RANBP2;LOC105371242;PPIAL4A	moderate;moderate;moderate;moderate;moderate;low;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7768 (FBgn0036415). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:14218204..14218974. It has the cytological map location 70D4. Protein features are: Cyclophilin-like domain; Cyclophilin-type peptidyl-prolyl cis-trans isomerase; Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain; Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site. Its molecular function is described by: peptidyl-prolyl cis-trans isomerase activity. It is involved in the biological process described with: protein peptidyl-prolyl isomerization; protein folding. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the pupal period, in adult male stages.  "
FBgn0039778	Jon99Fi	-0.726803854	0.051487112	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Jonah 99Fi is referred to in FlyBase by the symbol Dmel\Jon99Fi (CG18030, FBgn0039778). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:30488963..30489895. It has the cytological map location 99F6. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is unknown. It is involved in the biological process described with: proteolysis. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period.  "
FBgn0046874	Pif1B	-0.721879161	0.042159777	0.999936032	NA	NA	NA	DNA-binding with transcription factor activity	NA	NA	"The gene PFTAIRE-interacting factor 1B is referred to in FlyBase by the symbol Dmel\Pif1B (CG33720, FBgn0046874). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is 3R:8774286..8801176. It has the cytological map location 85B1. Its molecular function is described by: protein binding. It is involved in the biological process described with: . 7 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late pupal stages, in adult male stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0015929	dpa	-0.721141754	0.084982254	0.999936032	NA	MCM4	high	NA	NA	NA	"The gene disc proliferation abnormal is referred to in FlyBase by the symbol Dmel\dpa (CG1616, FBgn0015929). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:7496702..7500145. It has the cytological map location 43C6-43C7. Protein features are: AAA+ ATPase domain; MCM N-terminal domain; MCM OB domain; MCM domain; Mini-chromosome maintenance complex protein 4; Mini-chromosome maintenance protein; Mini-chromosome maintenance, conserved site; Nucleic acid-binding, OB-fold; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: ATP binding; 3'-5' DNA helicase activity; DNA binding. It is involved in the biological process described with: mitotic spindle organization; DNA replication; DNA replication initiation. 18 alleles are reported. The phenotypes of these alleles manifest in: central nervous system; chromosome, centromeric region; imaginal disc; trichogen cell; mitotic metaphase; mitotic cell cycle; mesothoracic tergum; spindle. The phenotypic classes of alleles include: viable; visible; some die during pupal stage; lethal - all die before end of pupal stage; wild-type. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0024179	wit	-0.71661459	0.078250616	0.999936032	NA	BMPR2;AMHR2;ACVR2A;ACVR2B;TGFBR2	high;moderate;low;low;low	NA	transmembrane protein	NA	"The gene wishful thinking is referred to in FlyBase by the symbol Dmel\wit (CG10776, FBgn0024179). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:4064152..4071717. It has the cytological map location 64A5. Protein features are: Activin types I and II receptor domain; Protein kinase domain; Protein kinase, ATP binding site; Protein kinase-like domain; Ser/Thr protein kinase, TGFB receptor. Its molecular function is described by: transforming growth factor beta receptor activity, type II; ATP binding; protein kinase activity; transmembrane receptor protein serine/threonine kinase activity; signal transducer, downstream of receptor, with serine/threonine kinase activity. It is involved in the biological process described with 11 unique terms, many of which group under: signaling; trans-synaptic signaling; single organism signaling; cell morphogenesis involved in neuron differentiation; protein modification process; cellular macromolecule metabolic process; positive regulation of developmental process; transmembrane receptor protein serine/threonine kinase signaling pathway; anterograde trans-synaptic signaling; neurogenesis; regulation of cellular process. 42 alleles are reported. The phenotypes of these alleles manifest in: synapse; neuromuscular junction; tarsal segment; non-connected functional system; embryonic/larval neuromuscular junction; sensory system; anatomical group; eo-type sensillum; wing vein L5; chaeta; apterous-expressing neuron of the lateral cluster of the thorax Ap4. The phenotypic classes of alleles include: increased mortality; lethal; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed during early pupal stages.  "
FBgn0030769	CG13012	-0.715969788	0.075438261	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG13012 (FBgn0030769). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is X:16668818..16676753. It has the cytological map location 15A1. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during early pupal stages.
FBgn0031771	ND-51	-0.714965805	0.055718707	0.999936032	NA	NDUFV1	high	NA	NA	NA	"The gene NADH dehydrogenase (ubiquinone) 51 kDa subunit is referred to in FlyBase by the symbol Dmel\ND-51 (CG9140, FBgn0031771). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:6060842..6062757. It has the cytological map location 26B4. Protein features are: NADH ubiquinone oxidoreductase, F subunit; NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain; NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain; NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site; Soluble ligand binding domain. Its molecular function is described by: NADH dehydrogenase activity; FMN binding; NADH dehydrogenase (ubiquinone) activity; 4 iron, 4 sulfur cluster binding; NAD binding. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone. 7 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: increased mortality during development; phenotype; lethal; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 06-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0031629	Clect27	-0.713942379	0.069897235	0.999936032	NA	SELL	low	NA	NA	NA	"The gene C-type lectin 27kD is referred to in FlyBase by the symbol Dmel\Clect27 (CG3244, FBgn0031629). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:4796600..4801923. It has the cytological map location 25A6. Protein features are: C-type lectin fold; C-type lectin, conserved site; C-type lectin-like; C-type lectin-like/link domain. Its molecular function is described by: carbohydrate binding. The biological processes in which it is involved are not known. 4 alleles are reported. The phenotypes of these alleles manifest in: wing; anterior crossvein. The phenotypic classes of alleles include: fertile; lethal; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of low expression.  Peak expression observed within 12-24 hour embryonic stages.  "
FBgn0036553	CG17027	-0.712460194	0.0878042	0.999936032	NA	IMPA1;IMPA2	moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17027 (FBgn0036553). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:15980100..15981888. It has the cytological map location 72C1. Protein features are: Inositol monophosphatase; Inositol monophosphatase, Lithium-sensitive; Inositol monophosphatase, conserved site; Inositol monophosphatase, metal-binding site; Inositol monophosphatase-like. Its molecular function is described by: inositol monophosphate 1-phosphatase activity. It is involved in the biological process described with: phosphatidylinositol phosphorylation; inositol metabolic process; dephosphorylation; inositol phosphate dephosphorylation; signal transduction. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal - majority die; pain response defective; some die during pupal stage; partially lethal; short lived; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the larval period, during early pupal stages.  "
FBgn0038938	CG7084	-0.712143963	0.066759907	0.999936032	NA	SLC22A4;SLC22A5;SLC22A2;SV2C;SV2B;SLC22A24;SLC22A7;SLC22A10;SLC22A12;SLC22A25;SLC22A11;SLC22A9;SLC22A23;SVOP;SLC22A8;SLC22A6;SLC22A1	low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7084 (FBgn0038938). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 3R:22298805..22304420. It has the cytological map location 94A4. Protein features are: Major facilitator superfamily domain; Major facilitator,  sugar transporter-like. Its molecular function is described by: organic anion transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. 4 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; embryonic/larval neuroblast; mesothoracic tergum. The phenotypic classes of alleles include: increased mortality; viable; increased mortality during development; phenotype; partially lethal - majority die; locomotor behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed in adult male stages.  "
FBgn0034497	Mpcp1	-0.711212081	0.09060437	0.999936032	NA	SLC25A3	high	NA	NA	NA	"The gene Mitochondrial phosphate carrier protein 1 is referred to in FlyBase by the symbol Dmel\Mpcp1 (CG9090, FBgn0034497). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:20279066..20281127. It has the cytological map location 56F15-56F16. Protein features are: Mitochondrial carrier domain; Mitochondrial substrate/solute carrier. Its molecular function is described by: phosphate ion transmembrane transporter activity. It is involved in the biological process described with: phosphate ion transport; mitochondrial transport. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very low expression.  Peak expression observed during late pupal stages, in stages of adults of both sexes.  "
FBgn0028516	ZnT35C	-0.708236565	0.078163945	0.999936032	NA	SLC30A2;SLC30A8;SLC30A3;SLC30A4	high;moderate;moderate;low	NA	transmembrane protein	NA	"The gene Zinc transporter 35C is referred to in FlyBase by the symbol Dmel\ZnT35C (CG3994, FBgn0028516). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:15228728..15247714. It has the cytological map location 35C4-35C5. Protein features are: Cation efflux protein; Cation efflux protein, cytoplasmic domain. Its molecular function is described by: zinc efflux transmembrane transporter activity; metal ion transmembrane transporter activity; zinc ion transmembrane transporter activity. It is involved in the biological process described with: detoxification of zinc ion; response to zinc ion; cellular zinc ion homeostasis; regulation of sequestering of zinc ion; zinc II ion transmembrane transport. 20 alleles are reported. The phenotype of these alleles manifest in: melanotic mass. The phenotypic classes of alleles include: chemical resistant; chemical sensitive; melanotic mass phenotype; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0031907	CG5171	-0.705027984	0.091255096	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5171 (FBgn0031907). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (2 unique). Gene sequence location is 2L:7401335..7404727. It has the cytological map location 27F3. Protein features are: HAD-like domain; HAD-superfamily hydrolase, subfamily IIB; Trehalose-phosphatase. Its molecular function is described by: trehalose-phosphatase activity. It is involved in the biological process described with: trehalose biosynthetic process; trehalose metabolism in response to stress. 8 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 06-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0051272	CG31272	-0.703506934	0.093055104	0.999936032	NA	SV2A	moderate	Maybe TF	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31272 (FBgn0051272). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:10756296..10759398. It has the cytological map location 86C5. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain. Its molecular function is described by: substrate-specific transmembrane transporter activity; lipase activity. It is involved in the biological process described with: transmembrane transport; lipid metabolic process. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0011822	Pgcl	-0.702000642	0.061160958	0.999936032	NA	CTSE;PGC;PGA5;REN;CTSD;NAPSA;PGA4;PGA3	moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"The gene Pepsinogen C-like is referred to in FlyBase by the symbol Dmel\Pgcl (CG13374, FBgn0011822). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:436139..437448. It has the cytological map location 1B2. Protein features are: Aspartic peptidase A1 family; Aspartic peptidase domain; Aspartic peptidase, active site; Cathepsin E; Peptidase family A1 domain. Its molecular function is described by: aspartic-type endopeptidase activity. It is involved in the biological process described with: protein catabolic process; establishment of imaginal disc-derived wing hair orientation; protein autoprocessing; proteolysis; Wnt signaling pathway. 7 alleles are reported. The phenotypes of these alleles manifest in: wing hair; wing margin. The phenotypic classes of alleles include: planar polarity defective; lethal - all die during larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0031461	daw	-0.700567708	0.095413065	0.999936032	NA	TGFB1;INHBE;INHBC;TGFB2;INHBB;INHBA;TGFB3	high;low;low;moderate;low;low;low	NA	NA	NA	"The gene dawdle is referred to in FlyBase by the symbol Dmel\daw (CG16987, FBgn0031461). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:2805261..2812376. It has the cytological map location 23B1-23B2. Protein features are: Cystine-knot cytokine; TGF-beta, propeptide; Transforming growth factor beta, conserved site; Transforming growth factor-beta, C-terminal; Transforming growth factor-beta-related. Its molecular function is described by: cytokine activity; growth factor activity; transforming growth factor beta receptor binding. It is involved in the biological process described with 11 unique terms, many of which group under: multicellular organismal process; activin receptor signaling pathway; secretion by cell; apoptotic process; cellular response to chemical stimulus; negative regulation of metabolic process; regulation of protein localization; aging; cell differentiation; regulation of peptide secretion; anatomical structure development; negative regulation of catabolic process. 31 alleles are reported. The phenotypes of these alleles manifest in: multi-cell-component structure; adult; peripheral nervous system; cell component; abdomen; ganglion; circulatory system; neuromuscular junction; somatic muscle; region of integument; embryonic/larval digestive system; organ system. The phenotypic classes of alleles include: increased mortality; phenotype; some die during larval stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, in adult male stages.  "
FBgn0038845	CG10827	-0.700338139	0.058950532	0.999936032	ALPI	ALPL;ALPP;ALPPL2;ALPI	high;moderate;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10827 (FBgn0038845). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:21005160..21006990. It has the cytological map location 93B3. Protein features are: Alkaline phosphatase; Alkaline phosphatase, active site; Alkaline phosphatase-like, alpha/beta/alpha; Alkaline-phosphatase-like, core domain. Its molecular function is described by: alkaline phosphatase activity. It is involved in the biological process described with: dephosphorylation. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0039358	CG5028	-0.699954473	0.062672556	0.999936032	IDH3G	IDH3G;IDH3B	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5028 (FBgn0039358). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 3R:25680845..25683780. It has the cytological map location 96E9. Protein features are: Isocitrate dehydrogenase NAD-dependent; Isopropylmalate dehydrogenase-like domain. Its molecular function is described by: isocitrate dehydrogenase (NAD+) activity. It is involved in the biological process described with: tricarboxylic acid cycle. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0266486	CG45085	-0.699950761	0.068083137	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG45085 (FBgn0266486). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:9186670..9192096. It has the cytological map location 45B3. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available.
FBgn0033079	Fmo-2	-0.698708101	0.061750994	0.999936032	NA	FMO5;FMO2;FMO1;FMO3;FMO4	moderate;high;moderate;moderate;moderate	NA	NA	NA	"The gene Flavin-containing monooxygenase 2 is referred to in FlyBase by the symbol Dmel\Fmo-2 (CG3174, FBgn0033079). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:6642418..6645098. It has the cytological map location 42B2. Protein features are: FAD/NAD(P)-binding domain; Flavin monooxygenase FMO; Flavin monooxygenase-like. Its molecular function is described by: N,N-dimethylaniline monooxygenase activity; monooxygenase activity; flavin adenine dinucleotide binding; NADP binding. It is involved in the biological process described with: oxidation-reduction process. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: short lived; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 12-18 embryonic stages, during early larval stages, during late pupal stages.  "
FBgn0002174	l(2)tid	-0.695953119	0.065689806	0.999936032	NA	DNAJA3	high	NA	NA	NA	"The gene lethal (2) tumorous imaginal discs is referred to in FlyBase by the symbol Dmel\l(2)tid (CG5504, FBgn0002174). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (all unique). Gene sequence location is 2R:23706913..23709026. It has the cytological map location 59F6. Protein features are: Chaperone DnaJ; Chaperone DnaJ, C-terminal; DnaJ domain; DnaJ domain, conserved site; HSP40/DnaJ peptide-binding; Heat shock protein DnaJ, cysteine-rich domain. Its molecular function is described by: unfolded protein binding; patched binding; ATP binding; heat shock protein binding. It is involved in the biological process described with: mitochondrion organization; sleep; response to heat; smoothened signaling pathway; protein folding. 14 alleles are reported. The phenotypes of these alleles manifest in: wing disc; imaginal disc. The phenotypic classes of alleles include: some die during pupal stage; lethal - all die before end of pupal stage; wild-type; tumorigenic; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0052364	tut	-0.694297134	0.098062299	0.999936032	NA	NA	NA	NA	NA	NA	"The gene tumorous testis is referred to in FlyBase by the symbol Dmel\tut (CG32364, FBgn0052364). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:8209577..8210743. It has the cytological map location 66B13-66C1. Protein features are: RNA recognition motif domain. Its molecular function is described by: RNA binding. It is involved in the biological process described with: male germline stem cell symmetric division; negative regulation of translation. 8 alleles are reported. The phenotypes of these alleles manifest in: testis; spermatogonium. The phenotypic classes of alleles include: male sterile; viable; increased cell number. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0031701	TotM	-0.694183468	0.043715972	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Turandot M is referred to in FlyBase by the symbol Dmel\TotM (CG14027, FBgn0031701). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:5329857..5330464. It has the cytological map location 25D6. Protein features are: Stress-inducible humoral factor Turandot. Its molecular function is unknown. It is involved in the biological process described with: response to heat; response to bacterium; defense response to Gram-positive bacterium; cellular response to heat. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed in adult female stages.  "
FBgn0031703	CG12512	-0.691048856	0.069877468	0.999936032	ACSF2	ACSF2	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12512 (FBgn0031703). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:5339132..5342234. It has the cytological map location 25D6. Protein features are: AMP-binding enzyme, C-terminal domain; AMP-binding, conserved site; AMP-dependent synthetase/ligase. Its molecular function is described by: catalytic activity. It is involved in the biological process described with: metabolic process. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during early larval stages, in adult male stages.  "
FBgn0051781	CR31781	-0.690278076	0.091399951	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CR31781 (FBgn0051781). It is a non_protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts. Gene sequence location is 2L:16869346..16878300. It has the cytological map location 36B3. Its molecular function is unknown. It is involved in the biological process described with: lateral inhibition. 4 alleles are reported. The phenotype of these alleles manifest in: chaeta. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0040060	yip7	-0.689861535	0.061656417	0.999936032	NA	KLK3	low	NA	NA	NA	"The gene yippee interacting protein 7 is referred to in FlyBase by the symbol Dmel\yip7 (CG6457, FBgn0040060). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:6035216..6036175. It has the cytological map location 65A3. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of extremely low expression.  Peak expression observed during late larval stages, in stages of adults of both sexes.  "
FBgn0036764	CG5535	-0.689738697	0.0758788	0.999936032	NA	SLC7A1;SLC7A3;SLC7A2;SLC7A4;SLC7A14	moderate;moderate;moderate;moderate;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5535 (FBgn0036764). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:17852624..17856794. It has the cytological map location 75A4. Protein features are: Amino acid/polyamine transporter I; Cationic amino acid transporter, C-terminal. Its molecular function is described by: amino acid transmembrane transporter activity. It is involved in the biological process described with: amino acid transmembrane transport. 8 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0039864	CG11550	-0.689726356	0.089636352	0.999936032	NA	TTPAL;CLVS1;RLBP1;CLVS2;TTPA	moderate;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11550 (FBgn0039864). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:31678147..31679880. It has the cytological map location 100D1. Protein features are: CRAL-TRIO lipid binding domain; CRAL/TRIO, N-terminal domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages.  "
FBgn0029648	CG3603	-0.687950874	0.077446581	0.999936032	NA	HSD17B8;CBR4	high;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3603 (FBgn0029648). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:2948034..2949120. It has the cytological map location 3C3. Protein features are: NAD(P)-binding domain; Short-chain dehydrogenase/reductase SDR; Short-chain dehydrogenase/reductase, conserved site. Its molecular function is described by: oxidoreductase activity. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0020370	TppII	-0.687797327	0.084090675	0.999936032	NA	TPP2	high	NA	NA	NA	"The gene tripeptidyl-peptidase II is referred to in FlyBase by the symbol Dmel\TppII (CG3991, FBgn0020370). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 2R:13152885..13159141. It has the cytological map location 49F4. Protein features are: Peptidase S8, subtilisin, His-active site; Peptidase S8, subtilisin, Ser-active site; Peptidase S8, subtilisin-related; Peptidase S8/S53 domain; Peptidase S8A, tripeptidyl peptidase II; Peptidase S8A, tripeptidyl peptidase II, arthropoda; Tripeptidyl-peptidase II domain. Its molecular function is described by: tripeptidyl-peptidase activity; serine-type endopeptidase activity; exopeptidase activity. It is involved in the biological process described with: protein homooligomerization; proteolysis. 12 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: viable; visible; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0031693	Cyp4ac1	-0.687156829	0.066559169	0.999936032	NA	CYP4V2;CYP4A11;CYP4Z1;CYP4B1;CYP4F11;CYP4X1;CYP4F12;CYP4A22;CYP4F8;CYP19A1;CYP4F3;CYP4F2;CYP4F22	moderate;low;low;low;moderate;low;low;low;moderate;moderate;low;low;moderate	NA	transmembrane protein	NA	"The gene Cyp4ac1 is referred to in FlyBase by the symbol Dmel\Cyp4ac1 (CG14032, FBgn0031693). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:5264001..5265899. It has the cytological map location 25D2. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Its molecular function is described by: iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; heme binding. It is involved in the biological process described with: oxidation-reduction process. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period, in adult male stages.  "
FBgn0053258	CG33258	-0.685696132	0.067269157	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG33258 (FBgn0053258). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:16082551..16083638. It has the cytological map location 72D1. Protein features are: Chitin binding domain. Its molecular function is described by: chitin binding. It is involved in the biological process described with: chitin metabolic process. 5 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed in adults stages of both sexes.
FBgn0029588	CG14798	-0.685593642	0.10087401	0.999936032	NA	ALKBH7	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14798 (FBgn0029588). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:1692824..1693843. It has the cytological map location 2B7. Protein features are: Alpha-ketoglutarate-dependent dioxygenase alkB homologue 7. Its molecular function is unknown. It is involved in the biological process described with: regulation of mitochondrial membrane permeability involved in programmed necrotic cell death; cellular response to DNA damage stimulus. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0052207	hpRNA:CR32207	-0.685224261	0.093125408	0.999936032	NA	NA	NA	NA	NA	NA	"The gene hairpin RNA:CR32207 is referred to in FlyBase by the symbol Dmel\hpRNA:CR32207 (CR32207, FBgn0052207). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3L:19477329..19478720. It has the cytological map location 76B3. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, in stages of adults of both sexes.  "
FBgn0029932	CG4607	-0.684755824	0.065693954	0.999936032	NA	SLC2A8;SLC2A6;SLC2A10	moderate;moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4607 (FBgn0029932). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:7069413..7072689. It has the cytological map location 6F1-6F3. Protein features are: Major facilitator superfamily domain; Major facilitator,  sugar transporter-like; Sugar transporter, conserved site; Sugar/inositol transporter. Its molecular function is described by: sugar:proton symporter activity; glucose transmembrane transporter activity. It is involved in the biological process described with: glucose import; hexose transmembrane transport. 4 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: lethal; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during late larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0004893	bowl	-0.683739376	0.093721681	0.999936032	NA	OSR2;OSR1	moderate;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene brother of odd with entrails limited is referred to in FlyBase by the symbol Dmel\bowl (CG10021, FBgn0004893). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (1 unique). Gene sequence location is 2L:3771700..3784121. It has the cytological map location 24C3-24C4. Protein features are: Zinc finger C2H2-type. Its molecular function is described by: nucleic acid binding; RNA polymerase II transcription factor activity, sequence-specific DNA binding. It is involved in the biological process described with 14 unique terms, many of which group under: hindgut morphogenesis; terminal region determination; glucose metabolic process; animal organ development; anterior/posterior axis specification; regulation of cellular carbohydrate metabolic process; single-organism cellular process; imaginal disc-derived leg segmentation; positive regulation of transcription from RNA polymerase II promoter; hindgut development; blastoderm segmentation. 30 alleles are reported. The phenotypes of these alleles manifest in: adult external mesothorax; eye disc; proventriculus primordium; prepupa; pupa; pretarsus; photoreceptor; primordium; presumptive embryonic/larval integumentary system; prothoracic tarsal segment. The phenotypic classes of alleles include: lethal; female sterile; viable; visible; lethal - all die before end of embryonic stage; some die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 06-12 hour embryonic stages, during early pupal stages.  "
FBgn0040251	Ugt86Di	-0.683215973	0.10403255	0.999936032	NA	UGT1A3;UGT2B10;UGT2A3;UGT1A1;UGT2B4;UGT2B15;UGT2B28;UGT2A2;UGT2B17;UGT2B11;UGT2B7;UGT3A1;UGT8;UGT3A2;UGT1A4;UGT1A10;UGT1A7;UGT1A5;UGT1A9;UGT1A6;UGT1A8	moderate;moderate;moderate;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene Ugt86Di is referred to in FlyBase by the symbol Dmel\Ugt86Di (CG6658, FBgn0040251). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:11151026..11153849. It has the cytological map location 86D5. Protein features are: UDP-glucuronosyl/UDP-glucosyltransferase; UDP-glycosyltransferase family, conserved site. Its molecular function is described by: glucuronosyltransferase activity. It is involved in the biological process described with: metabolic process. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0030941	wgn	-0.682242872	0.085817807	0.999936032	NA	TNFRSF4	low	NA	transmembrane protein	NA	"The gene wengen is referred to in FlyBase by the symbol Dmel\wgn (CG6531, FBgn0030941). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:18624042..18634908. It has the cytological map location 17C5-17C6. Protein features are: TNFR/NGFR cysteine-rich region. Its molecular function is described by: protein binding; tumor necrosis factor-activated receptor activity. It is involved in the biological process described with: negative regulation of neuromuscular synaptic transmission; neuron cellular homeostasis; apoptotic process; photoreceptor cell axon guidance; cell surface receptor signaling pathway. 13 alleles are reported. The phenotypes of these alleles manifest in: photoreceptor cell R4; photoreceptor cell R2; medulla; lamina plexus; lamina; photoreceptor cell R5; photoreceptor cell R3; photoreceptor cell R8. The phenotypic classes of alleles include: fertile; viable; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 06-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0262028	CR42839	-0.676915183	0.085715786	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR42839 (FBgn0262028). It is a non_protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts. Gene sequence location is 3R:16004321..16008073. It has the cytological map location 89A12. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0038207	CG14356	-0.676503888	0.102798923	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG14356 (FBgn0038207). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:14130680..14132072. It has the cytological map location 88A9. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: flight defective; viable; visible; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during early larval stages.
FBgn0014343	mirr	-0.67522669	0.107105677	0.999936032	NA	IRX6;IRX5;IRX4;IRX1;IRX3;IRX2	moderate;high;moderate;moderate;moderate;low	DNA-binding with transcription factor activity(Homeobox)	NA	NA	"The gene mirror is referred to in FlyBase by the symbol Dmel\mirr (CG10601, FBgn0014343). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:12693639..12710249. It has the cytological map location 69D3-69D4. Protein features are: Homeobox KN domain; Homeobox domain; Homeobox domain-like; Homeobox, conserved site; Iroquois-class homeodomain protein. Its molecular function is described by: RNA polymerase II transcription factor activity, sequence-specific DNA binding; protein homodimerization activity; sequence-specific DNA binding; transcription factor activity, sequence-specific DNA binding. It is involved in the biological process described with 11 unique terms, many of which group under: generation of neurons; cellular developmental process; positive regulation of RNA metabolic process; negative regulation of cellular metabolic process; chorion-containing eggshell formation; cellular component morphogenesis; negative regulation of growth; cellular response to stimulus; instar larval or pupal morphogenesis; growth; post-embryonic animal organ development. 40 alleles are reported. The phenotypes of these alleles manifest in: egg operculum; nervous system; cell; dendrite; external encapsulating structure; trichome field; chorion; cell periphery; epithelial cell; somatodendritic compartment; embryonic abdomen. The phenotypic classes of alleles include: increased mortality; lethal - all die before end of first instar larval stage; phenotype; increased mortality during development; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-18 hour embryonic stages.  "
FBgn0051522	CG31522	-0.675176733	0.069418636	0.999936032	NA	ELOVL7;ELOVL1;ELOVL4;ELOVL2;ELOVL5	moderate;moderate;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31522 (FBgn0051522). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (3 unique). Gene sequence location is 3R:4441415..4462883. It has the cytological map location 82B1-82B2. Protein features are: ELO family. Its molecular function is described by: fatty acid elongase activity. It is involved in the biological process described with: fatty acid elongation, polyunsaturated fatty acid; fatty acid elongation; fatty acid elongation, monounsaturated fatty acid; very long-chain fatty acid biosynthetic process; fatty acid elongation, saturated fatty acid; sphingolipid biosynthetic process. 19 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 12-18 embryonic stages, during early pupal stages.  "
FBgn0052580	Muc14A	-0.671391095	0.100158245	0.999936032	NA	MUC16	high	NA	transmembrane protein	NA	"The gene Mucin 14A is referred to in FlyBase by the symbol Dmel\Muc14A (CG32580, FBgn0052580). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:16009114..16061722. It has the cytological map location 14A6. Its molecular function is described by: extracellular matrix structural constituent. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely low expression to a trough of no expression detected.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0035040	CG4741	-0.670793876	0.077536	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4741 (FBgn0035040). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 2R:24610801..24615158. It has the cytological map location 60D9. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the larval period, during early pupal stages.  "
FBgn0051373	CG31373	-0.670096188	0.087032911	0.999936032	NA	PDF	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31373 (FBgn0051373). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:10708487..10709364. It has the cytological map location 86C4. Protein features are: Peptide deformylase. Its molecular function is described by: peptide deformylase activity. It is involved in the biological process described with: N-terminal protein amino acid modification; peptidyl-methionine modification; co-translational protein modification. One allele is reported. No phenotypic data is available. The phenotypic classes of allele include: viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed during late pupal stages, in stages of adults of both sexes.  "
FBgn0034552	CG17999	-0.669457173	0.110396846	0.999936032	NA	ACSBG1;AACS;ACSF3	low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17999 (FBgn0034552). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:20847980..20849939. It has the cytological map location 57B3. Protein features are: AMP-binding enzyme, C-terminal domain; AMP-binding, conserved site; AMP-dependent synthetase/ligase. Its molecular function is described by: catalytic activity. It is involved in the biological process described with: metabolic process. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0053509	CG33509	-0.669092464	0.068094825	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG33509 (FBgn0053509). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:21084605..21086506. It has the cytological map location 39A1. Protein features are: CHK kinase-like; Protein kinase-like domain; Protein of unknown function DUF227. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed during late pupal stages, in stages of adults of both sexes.  "
FBgn0031514	CG3332	-0.66847884	0.074186209	0.999936032	NA	OTOP2;OTOP1;OTOP3	moderate;moderate;high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3332 (FBgn0031514). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 2L:3275800..3280534. It has the cytological map location 23E1. Protein features are: Otopetrin. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; wing. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0034093	CG15706	-0.667923257	0.079885232	0.999936032	NA	MFSD6L	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15706 (FBgn0034093). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is 2R:16223218..16230680. It has the cytological map location 52F11. Protein features are: Major facilitator superfamily associated domain; Major facilitator superfamily domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0085452	CG34423	-0.667667898	0.104414857	0.999936032	NA	ATPIF1	moderate	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG34423 (FBgn0085452). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:23358612..23359204. It has the cytological map location 59D8. Protein features are: Mitochondrial ATPase inhibitor. Its molecular function is described by: ATPase inhibitor activity; ATPase binding. It is involved in the biological process described with: heme biosynthetic process; negative regulation of ATPase activity. No alleles are reported. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during late pupal stages.
FBgn0000575	emc	-0.666316121	0.073262933	0.999936032	NA	ID4;ID1;ID2;ID3	high;moderate;moderate;moderate	DNA-binding with transcription factor activity(HLH)	NA	NA	"The gene extra macrochaetae is referred to in FlyBase by the symbol Dmel\emc (CG1007, FBgn0000575). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:749400..753492. It has the cytological map location 61C9. Protein features are: DNA-binding protein inhibitor; Myc-type, basic helix-loop-helix (bHLH) domain. Its molecular function is described by: transcriptional repressor activity, RNA polymerase II transcription factor binding; protein heterodimerization activity. It is involved in the biological process described with 24 unique terms, many of which group under: peripheral nervous system development; cell proliferation; cell-cell signaling; inter-male aggressive behavior; negative regulation of DNA binding; morphogenesis of embryonic epithelium; sexual reproduction; dorsal appendage formation; multi-organism behavior; compound eye photoreceptor fate commitment; chorion-containing eggshell pattern formation; negative regulation of binding. 107 alleles are reported. The phenotypes of these alleles manifest in: eye disc; sensory mother cell; germ layer; cell; larval thoracic segment; muscle cell; anatomical cluster; prepupa; embryonic/larval gut; external sensory organ precursor cell; extended germ band embryo; photoreceptor cell R4. The phenotypic classes of alleles include: partially lethal; increased mortality; stress response defective; phenotype; viable; lethal - all die before end of first instar larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages.  "
FBgn0031182	Cyp6t1	-0.666127725	0.079526366	0.999936032	NA	TBXAS1;CYP3A43;CYP3A4;CYP3A5;CYP3A7-CYP3A51P	moderate;low;low;low;low	NA	transmembrane protein	NA	"The gene Cyp6t1 is referred to in FlyBase by the symbol Dmel\Cyp6t1 (CG1644, FBgn0031182). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:21517434..21519218. It has the cytological map location 20A1. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Its molecular function is described by: iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; heme binding; oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0261089	Sytalpha	-0.66545373	0.109228885	0.999936032	NA	SYT10;SYT9;SYT3;SYT6;SYT15;SYT17	high;high;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene Synaptotagmin ‘± is referred to in FlyBase by the symbol Dmel\Syt‘± (CG5559, FBgn0261089). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 2L:17592260..17604387. It has the cytological map location 36D. Protein features are: C2 domain. Its molecular function is described by: calcium ion binding; clathrin binding; syntaxin binding; calcium-dependent phospholipid binding. It is involved in the biological process described with: vesicle-mediated transport; vesicle fusion; neurotransmitter secretion; calcium ion-regulated exocytosis of neurotransmitter; regulation of calcium ion-dependent exocytosis. 12 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: viable; visible; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0035186	CG13912	-0.664787048	0.10202031	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13912 (FBgn0035186). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:1189588..1190472. It has the cytological map location 61F3. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, during late larval stages.  "
FBgn0033728	Cpr49Ae	-0.66458629	0.105966461	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Cuticular protein 49Ae is referred to in FlyBase by the symbol Dmel\Cpr49Ae (CG8505, FBgn0033728). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:12402216..12405108. It has the cytological map location 49A2. Protein features are: Chitin-binding type R&R consensus; Insect cuticle protein. Its molecular function is described by: structural constituent of chitin-based larval cuticle; structural constituent of cuticle. It is involved in the biological process described with: chitin-based cuticle development. 3 alleles are reported. The phenotypes of these alleles manifest in: Z disc; myofibril; sarcomere; mesothoracic tergum. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; some die during pupal stage; visible; flightless. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages.  "
FBgn0029804	CG3097	-0.664583407	0.082152482	0.999936032	CPA6	CPA4;CPA6;CPA2;CPA5;CPA1;CPB2;CPA3;CPO;CPB1	high;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3097 (FBgn0029804). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:5765855..5770780. It has the cytological map location 5B8-5C2. Protein features are: Carboxypeptidase, activation peptide; Insect gut carboxypeptidase-like, carboxypeptidase domain; Peptidase M14, carboxypeptidase A; Protease propeptides/proteinase inhibitor I9. Its molecular function is described by: zinc ion binding; metallocarboxypeptidase activity. It is involved in the biological process described with: proteolysis. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: short lived; fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages, during early larval stages, during late pupal stages.  "
FBgn0030946	CG6659	-0.663718059	0.073515709	0.999936032	NA	DPY19L1;DPY19L2;DPY19L4;DPY19L3;DPY19L2P2	high;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6659 (FBgn0030946). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:18653392..18657286. It has the cytological map location 17C7-17D1. Protein features are: C-mannosyltransferase Dpy-19; Dpy-19/Dpy-19-like. Its molecular function is described by: mannosyltransferase activity. It is involved in the biological process described with: protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan. 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; flightless; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in stages of adults of both sexes.  "
FBgn0033214	CG1941	-0.663116437	0.074177719	0.999936032	MOGAT2	MOGAT2;DGAT2L6;AWAT2;DGAT2;MOGAT1;AWAT1;MOGAT3;DGAT2L7P	moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1941 (FBgn0033214). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2R:7709873..7711981. It has the cytological map location 43E12. Protein features are: Diacylglycerol acyltransferase. Its molecular function is described by: transferase activity, transferring acyl groups other than amino-acyl groups. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during pupal stage; partially lethal; partially lethal - majority die; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages.  "
FBgn0031865	Nha1	-0.662801397	0.076279104	0.999936032	SLC9B2	SLC9B2;SLC9B1;SLC9B1P1	high;moderate;moderate	NA	transmembrane protein	NA	"The gene Na<sup>+</sup>/H<sup>+</sup> hydrogen antiporter 1 is referred to in FlyBase by the symbol Dmel\Nha1 (CG10806, FBgn0031865). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:6860905..6870389. It has the cytological map location 27C1. Protein features are: Cation/H+ exchanger. Its molecular function is described by: sodium:proton antiporter activity; chloride transmembrane transporter activity. It is involved in the biological process described with: renal sodium ion transport; transmembrane transport. 8 alleles are reported. The phenotype of these alleles manifest in: adult Malpighian tubule. The phenotypic classes of alleles include: partially lethal - majority live; viable; fertile; osmotic stress response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during late larval stages.  "
FBgn0035695	CG10226	-0.662791752	0.087893854	0.999936032	ABCB4	ABCB11;ABCB4;ABCB5;ABCB1;ABCB8	moderate;moderate;moderate;moderate;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10226 (FBgn0035695). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:6234323..6240068. It has the cytological map location 65A10. Protein features are: AAA+ ATPase domain; ABC transporter type 1, transmembrane domain; ABC transporter, conserved site; ABC transporter-like; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: ATP binding; xenobiotic-transporting ATPase activity; efflux transmembrane transporter activity. It is involved in the biological process described with: xenobiotic transport; response to toxic substance; renal tubular secretion; transmembrane transport. 7 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: visible; viable; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0032701	CG10341	-0.661911343	0.083379426	0.999936032	NA	NAF1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10341 (FBgn0032701). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:18698714..18700645. It has the cytological map location 37A1. Protein features are: H/ACA ribonucleoprotein complex, subunit Gar1/Naf1; Translation protein, beta-barrel domain. Its molecular function is described by: RNA binding. It is involved in the biological process described with: ribosome biogenesis; pseudouridine synthesis. 5 alleles are reported. The phenotype of these alleles manifest in: ganglion mother cell. The phenotypic classes of alleles include: lethal - all die during embryonic stage; neuroanatomy defective; viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0033048	CG7881	-0.661641271	0.092707008	0.999936032	NA	SLC17A3;SLC17A4;SLC17A1;SLC17A5	moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7881 (FBgn0033048). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:5960275..5966856. It has the cytological map location 42A4. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain. Its molecular function is described by: transmembrane transporter activity. It is involved in the biological process described with: anion transport; transmembrane transport. 8 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: viable; body color defective; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, in adult male stages.  "
FBgn0011297	l(2)not	-0.661630764	0.081424926	0.999936032	ALG3	ALG3	high	NA	transmembrane protein	NA	"The gene lethal (2) neighbor of tid is referred to in FlyBase by the symbol Dmel\l(2)not (CG4084, FBgn0011297). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:23705439..23709792. It has the cytological map location 59F6. Protein features are: Glycosyltransferase, ALG3. Its molecular function is described by: alpha-1,3-mannosyltransferase activity. The biological processes in which it is involved are not known. 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0034501	CG13868	-0.660246176	0.07903549	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13868 (FBgn0034501). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:20308777..20316917. It has the cytological map location 56F16. Its molecular function is unknown. It is involved in the biological process described with: sleep. 8 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 12-24 hour embryonic stages, in adult male stages.  "
FBgn0032615	CG6012	-0.659011377	0.090767695	0.999936032	NA	HSDL1;HSD17B3;HSD17B12	moderate;moderate;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6012 (FBgn0032615). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:16860029..16861489. It has the cytological map location 36B2. Protein features are: NAD(P)-binding domain; Short-chain dehydrogenase/reductase SDR. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period.  "
FBgn0033274	CG14757	-0.658961406	0.110957018	0.999936032	SDHAF2	SDHAF2	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14757 (FBgn0033274). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:8172364..8173613. It has the cytological map location 44B8. Protein features are: Flavinator of succinate dehydrogenase; Succinate dehydrogenase assembly factor 2, mitochondrial. Its molecular function is described by: copper ion binding. It is involved in the biological process described with: mitochondrial electron transport, succinate to ubiquinone; copper ion homeostasis; protein-FAD linkage; tricarboxylic acid cycle; mitochondrial respiratory chain complex II assembly. 5 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0037174	CG14457	-0.658914339	0.095512994	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG14457 (FBgn0037174). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3L:22669956..22680034. It has the cytological map location 79F5. Protein features are: Haemolymph juvenile hormone binding. Its molecular function is unknown. It is involved in the biological process described with: circadian rhythm; multicellular organism reproduction. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages.
FBgn0033853	CG6145	-0.658455274	0.078720795	0.999936032	NADK	NADK	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6145 (FBgn0033853). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (all unique). Gene sequence location is 2R:13537371..13547577. It has the cytological map location 50B1. Protein features are: ATP-NAD kinase, PpnK-type, all-beta; Inorganic polyphosphate/ATP-NAD kinase, domain 1; NAD kinase; NAD kinase/diacylglycerol kinase-like domain. Its molecular function is described by: NAD+ kinase activity. It is involved in the biological process described with: neuron projection morphogenesis; NAD metabolic process; NADP biosynthetic process. 22 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed during early pupal stages.  "
FBgn0027296	temp	-0.655721953	0.11617991	0.999936032	NA	PTAR1	high	NA	NA	NA	"The gene tempura is referred to in FlyBase by the symbol Dmel\temp (CG3073, FBgn0027296). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:2260207..2262515. It has the cytological map location 2F2. Protein features are: Protein prenyltransferase, alpha subunit. Its molecular function is described by: Rab geranylgeranyltransferase activity. It is involved in the biological process described with: protein geranylgeranylation; sensory organ development. 14 alleles are reported. The phenotypes of these alleles manifest in: external sensory organ precursor cell I; tormogen cell; eo neuron; mesothoracic tergum; chaeta. The phenotypic classes of alleles include: lethal - all die during third instar larval stage; some die during third instar larval stage; visible; some die during second instar larval stage; viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0000251	cad	-0.653083469	0.083728955	0.999936032	NA	CDX2;CDX1;CDX4	high;moderate;moderate	DNA-binding with transcription factor activity(Homeobox)	NA	NA	"The gene caudal is referred to in FlyBase by the symbol Dmel\cad (CG1759, FBgn0000251). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:20770731..20783135. It has the cytological map location 38E9-38E10. Protein features are: Helix-turn-helix motif; Homeobox domain; Homeobox domain, metazoa; Homeobox domain-like; Homeobox, conserved site. Its molecular function is described by: RNA polymerase II regulatory region sequence-specific DNA binding; transcription factor activity, sequence-specific DNA binding. It is involved in the biological process described with 16 unique terms, many of which group under: hindgut development; tube morphogenesis; segment specification; peptide metabolic process; animal organ morphogenesis; single-organism cellular process; axis specification; regulation of antimicrobial peptide biosynthetic process; renal tubule morphogenesis; analia development. 30 alleles are reported. The phenotypes of these alleles manifest in: embryonic abdominal segment; adult head; sensillum; embryonic/larval gut; melanotic mass; genital disc primordium; adult external thorax; female analia; cuboidal/columnar epithelium; embryonic imaginal precursor; adult thorax; head capsule. The phenotypic classes of alleles include: visible; viable; increased cell number; lethal; short lived; melanotic mass phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0023171	rnh1	-0.652023448	0.095154031	0.999936032	NA	RNASEH1	high	NA	NA	NA	"The gene ribonuclease H1 is referred to in FlyBase by the symbol Dmel\rnh1 (CG8729, FBgn0023171). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:7931054..7932380. It has the cytological map location 43F2. Protein features are: Ribonuclease H domain; Ribonuclease H-like domain; Ribonuclease H1, N-terminal; Ribonuclease H1, eukaryote; Ribosomal protein L9/RNase H1, N-terminal. Its molecular function is described by: nucleic acid binding; magnesium ion binding; RNA-DNA hybrid ribonuclease activity. It is involved in the biological process described with: DNA replication, removal of RNA primer. 10 alleles are reported. The phenotypes of these alleles manifest in: imaginal disc; prepupa; melanotic mass; embryonic/larval central nervous system. The phenotypic classes of alleles include: phenotype; increased mortality during development; increased mortality; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, in stages of adults of both sexes.  "
FBgn0061356	CG18003	-0.651391925	0.120710879	0.999936032	NA	HAO1;HAO2	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG18003 (FBgn0061356). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:10883547..10884936. It has the cytological map location 47C5. Protein features are: Aldolase-type TIM barrel; Alpha-hydroxy acid dehydrogenase, FMN-dependent; FMN-dependent alpha-hydroxy acid dehydrogenase, active site; FMN-dependent dehydrogenase. Its molecular function is described by: oxidoreductase activity; FMN binding. It is involved in the biological process described with: oxidation-reduction process. One allele is reported. No phenotypic data is available. The phenotypic classes of allele include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed during early larval stages, at stages throughout the pupal period, in adult male stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0040636	CG13255	-0.651084114	0.077025096	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13255 (FBgn0040636). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:20837488..20838839. It has the cytological map location 77F1. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during late larval stages, in adult male stages.  "
FBgn0043841	vir-1	-0.649507656	0.081433508	0.999936032	NA	NA	NA	NA	NA	NA	"The gene virus-induced RNA 1 is referred to in FlyBase by the symbol Dmel\vir-1 (CG31764, FBgn0043841). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (4 unique). Gene sequence location is 2L:12403270..12423439. It has the cytological map location 33E3-33E4. Its molecular function is unknown. It is involved in the biological process described with: defense response to virus. 11 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval salivary gland. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0031313	CG5080	-0.647714083	0.102014111	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5080 (FBgn0031313). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:1160290..1163886. It has the cytological map location 21F1. Its molecular function is described by: . It is involved in the biological process described with: . 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 06-18 hour embryonic stages, at stages throughout the pupal period.  "
FBgn0038922	Idh3b	-0.645594351	0.080476535	0.999936032	NA	IDH3B;IDH3G	high;low	NA	NA	NA	"The gene Isocitrate dehydrogenase 3b is referred to in FlyBase by the symbol Dmel\Idh3b (CG6439, FBgn0038922). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:22016391..22019382. It has the cytological map location 93F14-94A1. Protein features are: Isocitrate dehydrogenase NAD-dependent; Isopropylmalate dehydrogenase-like domain. Its molecular function is described by: isocitrate dehydrogenase (NAD+) activity. It is involved in the biological process described with: tricarboxylic acid cycle; ecdysone-mediated induction of salivary gland cell autophagic cell death; salivary gland cell autophagic cell death. 12 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval salivary gland; salivary gland; embryonic head; embryonic/larval midgut; nucleus; pupa; mitochondrion; embryo. The phenotypic classes of alleles include: phenotype; increased mortality during development; viable; some die during P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0036996	mag	-0.644640438	0.07791383	0.999936032	NA	LIPK;LIPJ;LIPF;LIPN;LIPA;LIPM	moderate;high;moderate;high;moderate;moderate	NA	NA	NA	"The gene magro is referred to in FlyBase by the symbol Dmel\mag (CG5932, FBgn0036996). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:20460683..20462274. It has the cytological map location 77C4. Protein features are: Alpha/Beta hydrolase fold; Lipase, eukaryotic; Partial AB-hydrolase lipase domain. Its molecular function is described by: sterol esterase activity. It is involved in the biological process described with: triglyceride homeostasis; cholesterol homeostasis; lipid metabolic process. 6 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during late larval stages.  "
FBgn0266350	CR44999	-0.642507998	0.089012935	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44999 (FBgn0266350). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is X:3373159..3522787. It has the cytological map location 3D2-3D5. Its molecular function is unknown. The biological processes in which it is involved are not known. 23 alleles are reported. No phenotypic data is available. No phenotypic class data is available.
FBgn0264574	Glut1	-0.641830199	0.118634283	0.999936032	NA	SLC2A3;SLC2A1;SLC2A4;SLC2A2;SLC2A14;SLC2A5;SLC2A9;SLC2A7;SLC2A11	high;high;moderate;moderate;moderate;moderate;moderate;low;low	NA	transmembrane protein	NA	"The gene Glucose transporter 1 is referred to in FlyBase by the symbol Dmel\Glut1 (CG43946, FBgn0264574). It is a protein_coding_gene from Drosophila melanogaster. It has 20 annotated transcripts and 20 polypeptides (18 unique). Gene sequence location is 3L:914074..993788. It has the cytological map location 61D4-61E1. Protein features are: Major facilitator superfamily domain; Major facilitator,  sugar transporter-like; Sugar transporter, conserved site; Sugar/inositol transporter. Its molecular function is described by: substrate-specific transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; positive regulation of peptide hormone secretion; adult chitin-containing cuticle pigmentation. 27 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; abdominal tergite 6; trichogen cell; abdominal tergite 5. The phenotypic classes of alleles include: stress response defective; increased mortality; phenotype; increased mortality during development."
FBgn0003162	Pu	-0.640930525	0.125604229	0.999936032	GCH1	GCH1	high	NA	NA	NA	"The gene Punch is referred to in FlyBase by the symbol Dmel\Pu (CG9441, FBgn0003162). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 2R:21175315..21182608. It has the cytological map location 57C7-57C8. Protein features are: GTP cyclohydrolase I; GTP cyclohydrolase I domain; GTP cyclohydrolase I, conserved site. Its molecular function is described by: zinc ion binding; GTP cyclohydrolase I regulator activity; GTP cyclohydrolase I activity; GTP binding. It is involved in the biological process described with: regulation of epithelial cell migration, open tracheal system; embryonic pattern specification; larval chitin-based cuticle development; compound eye pigmentation; preblastoderm mitotic cell cycle; tetrahydrobiopterin biosynthetic process; regulation of GTP cyclohydrolase I activity; pteridine biosynthetic process; tetrahydrofolate biosynthetic process; cuticle pigmentation. 84 alleles are reported. The phenotypes of these alleles manifest in: organelle; intracellular; intracellular organelle; embryonic/larval cuticle; developing material anatomical entity; epithelium; cell part; somatic cell; larval head; adult head; extended germ band embryo. The phenotypic classes of alleles include: visible; phenotype; increased mortality during development; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late larval stages, at stages throughout the pupal period.  "
FBgn0037612	CG8112	-0.639664598	0.091526561	0.999936032	SOAT1	SOAT1;SOAT2;DGAT1	high;moderate;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8112 (FBgn0037612). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3R:8712933..8715263. It has the cytological map location 85A8. Protein features are: Membrane bound O-acyl transferase, MBOAT; Sterol O-acyltransferase, ACAT/DAG/ARE types; Sterol O-acyltransferase, metazoa. Its molecular function is described by: cholesterol O-acyltransferase activity; O-acyltransferase activity. It is involved in the biological process described with: cholesterol homeostasis; cholesterol esterification; cholesterol metabolic process. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0016032	lbm	-0.63951775	0.118748026	0.999936032	NA	CD63	moderate	NA	transmembrane protein	NA	"The gene late bloomer is referred to in FlyBase by the symbol Dmel\lbm (CG2374, FBgn0016032). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:7049238..7051964. It has the cytological map location 42E6. Protein features are: Tetraspanin, EC2 domain; Tetraspanin/Peripherin. Its molecular function is unknown. It is involved in the biological process described with: cell surface receptor signaling pathway; synapse assembly. 15 alleles are reported. The phenotypes of these alleles manifest in: presynaptic ribbon; growth cone; RP3 motor neuron; synapse. The phenotypic classes of alleles include: neuroanatomy defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages.  "
FBgn0004919	gol	-0.638412021	0.12853727	0.999936032	NA	RNF150;RNF130;RNF149;RNF128;RNF133;RNF148;RNF215	high;moderate;moderate;moderate;moderate;moderate;moderate	Maybe TF	transmembrane protein	NA	"The gene goliath is referred to in FlyBase by the symbol Dmel\gol (CG2679, FBgn0004919). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 2R:25072627..25084347. It has the cytological map location 60F3. Protein features are: PA domain; Zinc finger, RING-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: ubiquitin protein ligase activity; zinc ion binding. It is involved in the biological process described with: mesoderm formation; protein ubiquitination. 9 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 06-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0044028	Notum	-0.638331403	0.109125463	0.999936032	NA	NOTUM	high	NA	NA	NA	"The gene Notum is referred to in FlyBase by the symbol Dmel\Notum (CG13076, FBgn0044028). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:16023480..16032752. It has the cytological map location 72C3-72D1. Protein features are: Alpha/Beta hydrolase fold; Pectinacetylesterase/NOTUM. Its molecular function is described by: palmitoleyl hydrolase activity. It is involved in the biological process described with: GPI anchor release; ventral cord development; proteoglycan metabolic process; regulation of compound eye pigmentation; Wnt signaling pathway; protein depalmitoleylation; negative regulation of Wnt signaling pathway; negative regulation of canonical Wnt signaling pathway; wing disc dorsal/ventral pattern formation. 23 alleles are reported. The phenotypes of these alleles manifest in: dorsal mesothorax; sensilla row; adult abdominal sensillum; wing blade ventral compartment; external sensory organ precursor cell; apterous-expressing neuron of the lateral cluster of the thorax Ap4; head; denticle; denticle field; denticle belt. The phenotypic classes of alleles include: phenotype; increased mortality during development; lethal; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0026428	HDAC6	-0.637918942	0.091726805	0.999936032	HDAC6	HDAC6;HDAC10;HDAC4;HDAC5;HDAC7;HDAC9	high;moderate;low;low;low;low	NA	NA	NA	"The gene Histone deacetylase 6 is referred to in FlyBase by the symbol Dmel\HDAC6 (CG6170, FBgn0026428). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (all unique). Gene sequence location is X:15333310..15340360. It has the cytological map location 13B6. Protein features are: Histone deacetylase domain; Histone deacetylase superfamily; Zinc finger, RING/FYVE/PHD-type; Zinc finger, UBP-type. Its molecular function is described by: zinc ion binding; deacetylase activity; histone deacetylase activity. It is involved in the biological process described with: tricarboxylic acid cycle; neurotransmitter secretion; histone deacetylation; respiratory electron transport chain; regulation of transcription, DNA-templated. 21 alleles are reported. The phenotypes of these alleles manifest in: t-bar; synapse; eye; synaptic vesicle. The phenotypic classes of alleles include: lethal; fertile; neurophysiology defective; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, in stages of adults of both sexes.  "
FBgn0011556	zetaTry	-0.636264244	0.082297643	0.999936032	NA	PRSS36;PRSS53;HPN;PRSS48	low;low;low;low	NA	transmembrane protein	NA	"The gene ‘_Trypsin is referred to in FlyBase by the symbol Dmel\‘_Try (CG12387, FBgn0011556). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:11339186..11340132. It has the cytological map location 47F3. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0053505	U3-55K	-0.634945367	0.126468734	0.999936032	NA	RRP9	high	NA	NA	NA	"The gene U3 small nuclear riboprotein factor 55K is referred to in FlyBase by the symbol Dmel\U3-55K (CG33505, FBgn0053505). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:14858845..14860758. It has the cytological map location 51C5. Protein features are: WD40 repeat; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: RNA binding; U3 snoRNA binding. It is involved in the biological process described with: rRNA processing. 3 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum; ganglion mother cell. The phenotypic classes of alleles include: neuroanatomy defective; lethal; lethal - all die during larval stage; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0010651	MFS14	-0.634687693	0.082999334	0.999936032	NA	SLC17A5;SLC17A4;SLC17A6;SLC17A8;SLC17A7;SLC17A3;SLC17A2;SLC17A1	moderate;moderate;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene Major Facilitator Superfamily Transporter 14 is referred to in FlyBase by the symbol Dmel\MFS14 (CG15095, FBgn0010651). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:18796975..18803727. It has the cytological map location 55F3-55F4. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain. Its molecular function is described by: transmembrane transporter activity. It is involved in the biological process described with: response to hypoxia; transmembrane transport; wing disc dorsal/ventral pattern formation; anion transport. 11 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 06-12 hour embryonic stages, during early larval stages, during early pupal stages.  "
FBgn0036030	CG6767	-0.634648654	0.08916593	0.999936032	PRPS1	PRPS1;PRPS2;PRPS1L1	high;high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6767 (FBgn0036030). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (6 unique). Gene sequence location is 3L:9683579..9696700. It has the cytological map location 67C4-67C5. Protein features are: Phosphoribosyl pyrophosphate synthetase, conserved site; Phosphoribosyltransferase domain; Phosphoribosyltransferase-like; Ribose-phosphate diphosphokinase; Ribose-phosphate pyrophosphokinase, N-terminal domain. Its molecular function is described by: magnesium ion binding; ribose phosphate diphosphokinase activity. It is involved in the biological process described with: ribonucleoside monophosphate biosynthetic process; nucleoside metabolic process; nucleotide biosynthetic process. 22 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0037045	CG10584	-0.634296204	0.115370772	0.999936032	NA	METTL22	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10584 (FBgn0037045). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:21030280..21031360. It has the cytological map location 78A2-78A5. Protein features are: Lysine methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase. Its molecular function is described by: . It is involved in the biological process described with: . 7 alleles are reported. The phenotypes of these alleles manifest in: Z disc; myofibril; sarcomere; embryonic/larval hemocyte. The phenotypic classes of alleles include: flight defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, during late pupal stages.  "
FBgn0022160	Gpo-1	-0.633493079	0.091971626	0.999936032	NA	GPD2	high	NA	NA	NA	"The gene Glycerophosphate oxidase-1 is referred to in FlyBase by the symbol Dmel\Gpo-1 (CG8256, FBgn0022160). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2R:15857752..15862755. It has the cytological map location 52C8. Protein features are: Alpha-glycerophosphate oxidase, C-terminal; EF-Hand 1, calcium-binding site; EF-hand domain; EF-hand domain pair; FAD dependent oxidoreductase; FAD-dependent glycerol-3-phosphate dehydrogenase; FAD/NAD(P)-binding domain. Its molecular function is described by: glycerol-3-phosphate dehydrogenase activity; calcium ion binding. It is involved in the biological process described with: glycerol metabolic process; flight behavior; glycerophosphate shuttle. 25 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; embryonic/larval neuroblast; ganglion mother cell; trichogen cell. The phenotypic classes of alleles include: partially lethal; increased mortality during development; phenotype; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0030481	CG1662	-0.633085409	0.09006445	0.999936032	MPV17L2	MPV17L2;PXMP2;MPV17	high;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1662 (FBgn0030481). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:13387563..13389332. It has the cytological map location 11F1. Protein features are: Mpv17/PMP22. Its molecular function is unknown. It is involved in the biological process described with: mitochondrial ribosome assembly. 5 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: visible; viable; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0036454	CG17839	-0.632480145	0.131416146	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17839 (FBgn0036454). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:14805136..14882224. It has the cytological map location 70F7-71A1. Protein features are: Domain of unknown function DB; Fibronectin type III; Immunoglobulin; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold. Its molecular function is unknown. The biological processes in which it is involved are not known. 16 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during late larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0036659	CG9701	-0.632248817	0.117431125	0.999936032	NA	LCTL;KL;LCT;KLB;GBA3	high;moderate;moderate;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9701 (FBgn0036659). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:16733546..16739364. It has the cytological map location 73C2. Protein features are: Glycoside hydrolase family 1; Glycoside hydrolase family 1, active site; Glycoside hydrolase superfamily; Glycosyl hydrolases family 1, N-terminal conserved site. Its molecular function is described by: beta-glucosidase activity. It is involved in the biological process described with: glycosyl compound metabolic process; carbohydrate metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the pupal period.  "
FBgn0038595	CG7142	-0.631657183	0.106406247	0.999936032	NA	HGF	low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7142 (FBgn0038595). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:18278181..18279522. It has the cytological map location 91A1. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period.  "
FBgn0002023	Lim3	-0.631504783	0.111237328	0.999936032	NA	LHX3;LHX4	high;high	DNA-binding with transcription factor activity(Homeobox)	NA	NA	"The gene Lim3 is referred to in FlyBase by the symbol Dmel\Lim3 (CG10699, FBgn0002023). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (4 unique). Gene sequence location is 2L:19079256..19108427. It has the cytological map location 37B13-37C1. Protein features are: Homeobox domain; Homeobox domain-like; Homeobox, conserved site; Zinc finger, LIM-type. Its molecular function is described by: sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated; nervous system development; regulation of cell cycle; motor neuron axon guidance. 31 alleles are reported. The phenotypes of these alleles manifest in: abdominal segmental nerve; abdominal intersegmental nerve; intersegmental nerve; transverse nerve; melanotic mass; wing. The phenotypic classes of alleles include: partially lethal; increased mortality; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 06-24 hour embryonic stages, during early larval stages.  "
FBgn0039519	Cyp6a18	-0.631418379	0.115446904	0.999936032	TBXAS1	TBXAS1;CYP3A43;CYP3A4;CYP3A5;CYP3A7-CYP3A51P;CYP3A7	moderate;moderate;moderate;moderate;low;low	NA	transmembrane protein	NA	"The gene Cyp6a18 is referred to in FlyBase by the symbol Dmel\Cyp6a18 (CG13977, FBgn0039519). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:27478675..27482904. It has the cytological map location 98A2. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Its molecular function is described by: oxidoreductase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; iron ion binding; heme binding. It is involved in the biological process described with: oxidation-reduction process. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period, during late pupal stages, in adult male stages.  "
FBgn0262717	Skeletor	-0.631165328	0.108595625	0.999936032	NA	THBD	low	NA	transmembrane protein	NA	"The gene Skeletor is referred to in FlyBase by the symbol Dmel\Skeletor (CG43161, FBgn0262717). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 3R:10686943..10696270. It has the cytological map location 86C4. Protein features are: DM13 domain; DOMON domain. Its molecular function is described by: dopamine beta-monooxygenase activity; structural molecule activity. It is involved in the biological process described with: spindle assembly; catecholamine metabolic process; nucleus organization. 6 alleles are reported. The phenotype of these alleles manifest in: male accessory gland secondary cell. The phenotypic classes of alleles include: viable; fertile."
FBgn0034053	Cyp4aa1	-0.630630785	0.105463524	0.999936032	NA	CYP4A11;CYP4Z1;CYP4B1;CYP4X1;CYP4A22;CYP19A1;CYP4V2;CYP4F11;CYP4F12;CYP46A1	moderate;moderate;moderate;moderate;moderate;moderate;low;low;low;moderate	NA	transmembrane protein	NA	"The gene Cyp4aa1 is referred to in FlyBase by the symbol Dmel\Cyp4aa1 (CG8302, FBgn0034053). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:15942864..15947266. It has the cytological map location 52D3-52D4. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group IV; Cytochrome P450, conserved site. Its molecular function is described by: iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; monooxygenase activity; heme binding. It is involved in the biological process described with: oxidation-reduction process. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, in stages of adults of both sexes.  "
FBgn0038475	Keap1	-0.629857221	0.118839201	0.999936032	KEAP1	KEAP1	high	NA	NA	NA	"The gene Keap1 is referred to in FlyBase by the symbol Dmel\Keap1 (CG3962, FBgn0038475). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:17073942..17079945. It has the cytological map location 89E11-89E12. Protein features are: BTB-kelch protein; BTB/Kelch-associated; BTB/POZ domain; Kelch repeat type 1; Kelch-type beta propeller; SKP1/BTB/POZ domain. Its molecular function is described by: actin binding; ubiquitin-protein transferase activity; protein homodimerization activity. It is involved in the biological process described with: protein autoubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; response to oxidative stress. 15 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: large body; developmental rate defective; oxidative stress response defective; long lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0040658	CG13516	-0.629447626	0.126922567	0.999936032	NA	LITAF	moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13516 (FBgn0040658). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:22669145..22670622. It has the cytological map location 58F7. Protein features are: LPS-induced tumour necrosis factor alpha factor. Its molecular function is described by: signal transducer activity. It is involved in the biological process described with: apoptotic process; signal transduction. No alleles are reported. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0034563	CG15649	-0.629288615	0.092783952	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG15649 (FBgn0034563). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:20972916..20974017. It has the cytological map location 57B5. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; chaeta. The phenotypic classes of alleles include: planar polarity defective; visible; viable; body color defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-18 embryonic stages.
FBgn0010389	htl	-0.629263725	0.133789242	0.999936032	NA	FGFR3;FGFR1;FGFR4;FGFR2;RET	high;moderate;moderate;moderate;low	NA	transmembrane protein	NA	"The gene heartless is referred to in FlyBase by the symbol Dmel\htl (CG7223, FBgn0010389). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:18045216..18052984. It has the cytological map location 90E2. Protein features are: Fibroblast growth factor receptor family; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold; Protein kinase domain; Protein kinase, ATP binding site; Protein kinase-like domain; Serine-threonine/tyrosine-protein kinase, catalytic domain; Tyrosine-protein kinase, active site; Tyrosine-protein kinase, catalytic domain. Its molecular function is described by: protein tyrosine kinase activity; fibroblast growth factor-activated receptor activity; ATP binding. It is involved in the biological process described with 32 unique terms, many of which group under: ameboidal-type cell migration; endodermal cell differentiation; renal system development; cellular macromolecule metabolic process; positive regulation of cellular process; regulation of cell morphogenesis; regulation of defense response; mesodermal cell fate determination; response to endogenous stimulus; defense response to other organism. 40 alleles are reported. The phenotypes of these alleles manifest in: supramolecular complex; oblique muscle; skeletal muscle of thorax; embryonic/larval neuromuscular junction; embryonic visceral muscle; ventral oblique muscle; prepupa; cell; trunk mesoderm derivative; myofibril; supramolecular polymer; embryonic/larval nervous system. The phenotypic classes of alleles include: majority die during larval stage; stress response defective; phenotype; increased mortality during development; visible; female semi-sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0266731	CR45204	-0.629123305	0.125810395	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45204 (FBgn0266731). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is X:10794338..10796292. It has the cytological map location 9F2. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0001341	l(1)1Bi	-0.628249282	0.134949587	0.999936032	NA	MYBBP1A	high	DNA-binding with transcription factor activity	NA	NA	"The gene lethal (1) 1Bi is referred to in FlyBase by the symbol Dmel\l(1)1Bi (CG6189, FBgn0001341). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:629773..633633. It has the cytological map location 1B12. Protein features are: Armadillo-like helical; Armadillo-type fold; DNA polymerase V. Its molecular function is described by: DNA-directed DNA polymerase activity; DNA binding. It is involved in the biological process described with: transcription, DNA-templated. 21 alleles are reported. The phenotype of these alleles manifest in: macrochaeta. The phenotypic classes of alleles include: lethal - all die before end of larval stage; increased mortality; phenotype; viable; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0040600	CG13631	-0.628006478	0.126056427	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13631 (FBgn0040600). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:24769351..24770933. It has the cytological map location 96A20. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. The phenotypic class of allele includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages, during late pupal stages.  "
FBgn0028622	qsm	-0.626990768	0.135708489	0.999936032	NA	NA	NA	NA	NA	NA	"The gene quasimodo is referred to in FlyBase by the symbol Dmel\qsm (CG13432, FBgn0028622). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:20563034..20583591. It has the cytological map location 57A5-57A6. Protein features are: Zona pellucida domain. Its molecular function is unknown. It is involved in the biological process described with: cell morphogenesis; locomotor rhythm. 19 alleles are reported. The phenotypes of these alleles manifest in: digestive system; optic lobe neuron; central nervous system; neuron projection bundle; trichogen cell; salivary gland; adult central nervous system; tormogen cell; adult brain; late embryo. The phenotypic classes of alleles include: increased mortality during development; phenotype; increased mortality; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0039084	CG10175	-0.625340308	0.13539468	0.999936032	NA	CES4A;CES2;NLGN2;CES5A;CES1;CEL;NLGN4X;NLGN1;NLGN3;NLGN4Y;CES3	low;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10175 (FBgn0039084). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 3R:23522264..23530986. It has the cytological map location 95A1. Protein features are: Alpha/Beta hydrolase fold; Carboxylesterase type B, active site; Carboxylesterase, type B; Lipase, GDXG, putative histidine active site. Its molecular function is described by: carboxylic ester hydrolase activity. It is involved in the biological process described with: metabolic process. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the pupal period.  "
FBgn0040257	Ugt86Dc	-0.625100922	0.097483332	0.999936032	NA	UGT2B10;UGT2B7;UGT1A3;UGT3A2;UGT1A6;UGT1A1;UGT2B4;UGT2B15;UGT2B28;UGT2A2;UGT2B17;UGT2B11;UGT2A3;UGT3A1;UGT8;UGT1A4;UGT1A10;UGT1A7;UGT1A5;UGT1A9;UGT1A8	moderate;moderate;moderate;moderate;moderate;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene Ugt86Dc is referred to in FlyBase by the symbol Dmel\Ugt86Dc (CG4739, FBgn0040257). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:11154626..11156513. It has the cytological map location 86D5. Protein features are: UDP-glucuronosyl/UDP-glucosyltransferase; UDP-glycosyltransferase family, conserved site. Its molecular function is described by: glucuronosyltransferase activity. It is involved in the biological process described with: metabolic process. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0012036	Aldh	-0.624789088	0.085489018	0.999936032	NA	ALDH2;ALDH1B1;ALDH1A1;ALDH1A2;ALDH1A3;ALDH16A1;ALDH8A1;ALDH1L2;ALDH1L1;ALDH9A1	high;moderate;moderate;moderate;moderate;moderate;moderate;low;low;moderate	NA	NA	NA	"The gene Aldehyde dehydrogenase is referred to in FlyBase by the symbol Dmel\Aldh (CG3752, FBgn0012036). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:9387389..9391567. It has the cytological map location 30B1. Protein features are: Aldehyde dehydrogenase N-terminal domain; Aldehyde dehydrogenase domain; Aldehyde dehydrogenase, cysteine active site; Aldehyde dehydrogenase, glutamic acid active site; Aldehyde/histidinol dehydrogenase. Its molecular function is described by: acetaldehyde dehydrogenase (acetylating) activity; aldehyde dehydrogenase (NAD) activity. It is involved in the biological process described with: negative regulation of neuron death; acetaldehyde metabolic process; response to ethanol; oxidation-reduction process; pyruvate metabolic process. 13 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; olfactory receptor neuron. The phenotypic classes of alleles include: fertile; stress response defective; phenotype; increased mortality during development; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0040321	GNBP3	-0.622404346	0.138640451	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene Gram-negative bacteria binding protein 3 is referred to in FlyBase by the symbol Dmel\GNBP3 (CG5008, FBgn0040321). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:8955021..8956551. It has the cytological map location 66E5. Protein features are: Beta-1,3-glucan-binding protein, N-terminal; Concanavalin A-like lectin/glucanase domain; Glycoside hydrolase family 16. Its molecular function is described by: signaling pattern recognition receptor activity; (1->3)-beta-D-glucan binding; lipopolysaccharide binding. It is involved in the biological process described with: carbohydrate metabolic process; regulation of innate immune response; response to fungus; detection of molecule of fungal origin; innate immune response-activating signal transduction. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: immune response defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during late larval stages, at stages throughout the pupal period.  "
FBgn0039509	bigmax	-0.620756662	0.096768879	0.999936032	MLX	MLX	high	DNA-binding with transcription factor activity(HLH)	NA	NA	"The gene bigmax is referred to in FlyBase by the symbol Dmel\bigmax (CG3350, FBgn0039509). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:27287366..27288526. It has the cytological map location 97F1. Protein features are: Max-like protein X; Myc-type, basic helix-loop-helix (bHLH) domain. Its molecular function is described by: transcription factor binding; protein dimerization activity; transcription factor activity, sequence-specific DNA binding. It is involved in the biological process described with: muscle organ development; regulation of transcription, DNA-templated; salivary gland cell autophagic cell death; dendrite morphogenesis; regulation of transcription from RNA polymerase II promoter; adult feeding behavior; regulation of glucose metabolic process; autophagic cell death. 11 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: increased mortality during development; phenotype; increased mortality; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 18-24 hour embryonic stages, during early pupal stages.  "
FBgn0039760	CG9682	-0.620495332	0.090621158	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG9682 (FBgn0039760). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:30250928..30252830. It has the cytological map location 99E3. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed during late larval stages.
FBgn0037807	CG6293	-0.620006758	0.124779705	0.999936032	NA	SLC23A1;SLC23A2;SLC23A3	high;moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6293 (FBgn0037807). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:10307806..10311613. It has the cytological map location 86A7. Protein features are: Xanthine/uracil permease; Xanthine/uracil/vitamin C permease. Its molecular function is described by: transporter activity. It is involved in the biological process described with: transmembrane transport. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0026196	nop5	-0.61987691	0.098055681	0.999936032	NA	NOP58	high	NA	NA	NA	"The gene nop5 is referred to in FlyBase by the symbol Dmel\nop5 (CG10206, FBgn0026196). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:6916753..6918743. It has the cytological map location 27C4. Protein features are: NOP5, N-terminal; NOSIC; Nop domain. Its molecular function is described by: snoRNA binding. It is involved in the biological process described with: rRNA processing; rRNA modification; cellular response to starvation. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during pupal stage; lethal - all die before end of pupal stage; viable; lethal; female sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0050118	Ttd14	-0.619247932	0.094665308	0.999936032	NA	NA	NA	NA	NA	NA	NA
FBgn0260942	bond	-0.619009504	0.105125416	0.999936032	NA	ELOVL7;ELOVL4;ELOVL1;ELOVL5;ELOVL2	moderate;low;low;low;low	NA	transmembrane protein	NA	"The gene james bond is referred to in FlyBase by the symbol Dmel\bond (CG6921, FBgn0260942). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:22550680..22556494. It has the cytological map location 94B4. Protein features are: ELO family; ELO family, conserved site. Its molecular function is described by: fatty acid elongase activity. It is involved in the biological process described with 13 unique terms, many of which group under: microtubule cytoskeleton organization; sphingolipid biosynthetic process; organelle assembly; fatty acid elongation, unsaturated fatty acid; gamete generation; very long-chain fatty acid biosynthetic process; actomyosin contractile ring assembly; biological regulation; assembly of actomyosin apparatus involved in cytokinesis; secondary metabolic process. 17 alleles are reported. The phenotypes of these alleles manifest in: Nebenkern derivative; spermatid; spermatocyte; spindle microtubule; Nebenkern. The phenotypic classes of alleles include: cell cycle defective; phenotype; viable; sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, in adult male stages.  "
FBgn0085481	CG34452	-0.61757111	0.12089424	0.999936032	NA	C1GALT1;C1GALT1C1	moderate;high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG34452 (FBgn0085481). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:15686352..15687902. It has the cytological map location 71F1. Protein features are: Fringe-like. Its molecular function is described by: glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity; galactosyltransferase activity. It is involved in the biological process described with: protein glycosylation; O-glycan processing, core 1. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0262733	Src64B	-0.616156567	0.114376323	0.999936032	NA	SRC;FYN;FGR;FRK;YES1;LCK;HCK;LYN;BLK;SLA;SLA2;PTK6;TYK2;JAK1;JAK2;JAK3;BMX;BTK;TEC;TXK;ABL1;ABL2;SRMS;ITK	high;high;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;low;low;low;low;low;low;low;low;low;low;moderate;low	NA	NA	NA	"The gene Src oncogene at 64B is referred to in FlyBase by the symbol Dmel\Src64B (CG7524, FBgn0262733). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (2 unique). Gene sequence location is 3L:4592447..4626196. It has the cytological map location 64B11-64B12. Protein features are: Protein kinase domain; Protein kinase, ATP binding site; Protein kinase-like domain; SH2 domain; SH3 domain; Serine-threonine/tyrosine-protein kinase, catalytic domain; Tyrosine-protein kinase, active site; Tyrosine-protein kinase, catalytic domain. Its molecular function is described by: receptor binding; protein tyrosine kinase activity; non-membrane spanning protein tyrosine kinase activity; ATP binding. It is involved in the biological process described with 35 unique terms, many of which group under: synaptic signaling; olfactory behavior; cell motility; immune response; salivary gland development; cell junction assembly; parallel actin filament bundle assembly; biological adhesion; negative regulation of cellular process; JNK cascade. 65 alleles are reported. The phenotypes of these alleles manifest in: follicle cell; adult labral segment; neuromere; cell junction; mushroom body alpha-lobe; egg; plasma membrane bounded cell projection; prepupa; pericardial cell; cell periphery; supramolecular complex. The phenotypic classes of alleles include: phenotype; fertile; increased mortality; lethal - all die before end of second instar larval stage; cell shape defective; semi-sterile; cell death defective."
FBgn0037912	sea	-0.615552524	0.089908765	0.999936032	NA	SLC25A1	high	NA	NA	NA	"The gene scheggia is referred to in FlyBase by the symbol Dmel\sea (CG6782, FBgn0037912). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 3R:11559896..11567054. It has the cytological map location 86E10. Protein features are: Mitochondrial carrier domain; Mitochondrial substrate/solute carrier. Its molecular function is described by: citrate transmembrane transporter activity. It is involved in the biological process described with: mitochondrial transport; citrate transport; mitochondrial citrate transport. 17 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval neuroblast; condensed chromosome. The phenotypic classes of alleles include: lethal; viable; mitotic cell cycle defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0036483	CG12316	-0.613883068	0.135203688	0.999936032	NA	MSL1	low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12316 (FBgn0036483). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:15131508..15136934. It has the cytological map location 71B5. Protein features are: Protein male-specific lethal-1. Its molecular function is unknown. It is involved in the biological process described with: histone H4-K16 acetylation; male courtship behavior, veined wing generated song production. 7 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval hemocyte. The phenotypic classes of alleles include: viable; song defective; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0031975	Tg	-0.612984162	0.132302935	0.999936032	TGM1	TGM1;TGM4;F13A1;TGM2;TGM6;TGM7;TGM3;TGM5;EPB42	high;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"The gene Transglutaminase is referred to in FlyBase by the symbol Dmel\Tg (CG7356, FBgn0031975). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:8011405..8026898. It has the cytological map location 28D3. Protein features are: Immunoglobulin E-set; Immunoglobulin-like fold; Protein-glutamine gamma-glutamyltransferase, animal; Transglutaminase, C-terminal; Transglutaminase, N-terminal; Transglutaminase-like. Its molecular function is described by: protein-glutamine gamma-glutamyltransferase activity. It is involved in the biological process described with: innate immune response; hemolymph coagulation; peptide cross-linking. 11 alleles are reported. The phenotypes of these alleles manifest in: interommatidial bristle; crossvein; eye; ommatidium; wing; tergite. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; partially lethal; short lived; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the pupal period.  "
FBgn0035313	CG13810	-0.612980033	0.117273342	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13810 (FBgn0035313). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:2185930..2187676. It has the cytological map location 62D2. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages.  "
FBgn0027109	NPF	-0.611852162	0.118364683	0.999936032	NA	NA	NA	NA	NA	NA	"The gene neuropeptide F is referred to in FlyBase by the symbol Dmel\NPF (CG10342, FBgn0027109). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:16609220..16611325. It has the cytological map location 89D5. Its molecular function is described by: neuropeptide F receptor binding; neuropeptide hormone activity. It is involved in the biological process described with 11 unique terms, many of which group under: behavior; circadian rhythm; rhythmic process; single-multicellular organism process; larval behavior; rhythmic behavior; signal transduction; single-organism behavior; regulation of biological process; locomotory behavior; sexual reproduction; regulation of response to nutrient levels; intraspecies interaction between organisms. 11 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: behavior defective; chemical sensitive; mating behavior defective; feeding behavior defective; viable; developmental rate defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during early pupal stages, in stages of adults of both sexes.  "
FBgn0010053	Jheh1	-0.611238301	0.092450239	0.999936032	NA	EPHX1	moderate	NA	transmembrane protein	NA	"The gene Juvenile hormone epoxide hydrolase 1 is referred to in FlyBase by the symbol Dmel\Jheh1 (CG15101, FBgn0010053). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:18853434..18855087. It has the cytological map location 55F7-55F8. Protein features are: Alpha/Beta hydrolase fold; Epoxide hydrolase; Epoxide hydrolase, N-terminal; Epoxide hydrolase-like. Its molecular function is described by: cis-stilbene-oxide hydrolase activity; juvenile hormone epoxide hydrolase activity. It is involved in the biological process described with: juvenile hormone catabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0042103	CG18746	-0.610895752	0.118368405	0.999936032	NA	ARRDC2;ARRDC4;TXNIP;ARRDC3;ARRDC1;ARRDC5	moderate;high;moderate;moderate;low;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG18746 (FBgn0042103). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:7788282..7790187. It has the cytological map location 84E1. Protein features are: Arrestin C-terminal-like domain; Arrestin-like, N-terminal; Immunoglobulin E-set. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0036576	CG5151	-0.608754082	0.108508365	0.999936032	NA	LDLRAD4	low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5151 (FBgn0036576). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 3L:16137802..16164701. It has the cytological map location 72D9. Its molecular function is unknown. The biological processes in which it is involved are not known. 10 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0039620	wat	-0.608094753	0.097009039	0.999936032	NA	FAR2;FAR1	moderate;high	NA	transmembrane protein	NA	"The gene waterproof is referred to in FlyBase by the symbol Dmel\wat (CG1443, FBgn0039620). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:28992977..29020406. It has the cytological map location 98F5. Protein features are: Fatty acyl-CoA reductase; Fatty acyl-CoA reductase, C-terminal; Male sterility, NAD-binding; NAD(P)-binding domain. Its molecular function is described by: long-chain-fatty-acyl-CoA reductase activity; fatty-acyl-CoA reductase (alcohol-forming) activity. It is involved in the biological process described with: long-chain fatty-acyl-CoA metabolic process; liquid clearance, open tracheal system; wax biosynthetic process; lumen formation, open tracheal system; oxidation-reduction process. 12 alleles are reported. The phenotypes of these alleles manifest in: tracheal lumen; taenidium; tracheal branch primordium. The phenotypic classes of alleles include: viable; short lived; fertile; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, during late pupal stages, in adult male stages.  "
FBgn0038009	CG17738	-0.608037654	0.144982344	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17738 (FBgn0038009). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:12270890..12271300. It has the cytological map location 87B4. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during late larval stages.  "
FBgn0025837	CG17636	-0.607799572	0.14773758	0.999936032	NA	GGT1;GGT2;GGT5;GGTLC2;GGTLC1;GGT7;GGT3P;GGT6	moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17636 (FBgn0025837). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is X:124370..126714. It has the cytological map location 1A1. Protein features are: Gamma-glutamyltranspeptidase; Nucleophile aminohydrolases, N-terminal. Its molecular function is described by: glutathione hydrolase activity. It is involved in the biological process described with: glutathione catabolic process. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0033397	Cyp4p3	-0.607594986	0.139197888	0.999936032	NA	CYP4A11;CYP4Z1;CYP4B1;CYP4X1;CYP4A22;CYP4V2;CYP4F11;CYP4F12;CYP19A1;CYP4F8;CYP4F3;CYP4F2;CYP4F22	moderate;high;high;high;moderate;low;moderate;low;moderate;moderate;low;low;moderate	NA	transmembrane protein	NA	"The gene Cyp4p3 is referred to in FlyBase by the symbol Dmel\Cyp4p3 (CG10843, FBgn0033397). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:9242320..9244410. It has the cytological map location 45B7. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Its molecular function is described by: heme binding; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. It is involved in the biological process described with: oxidation-reduction process. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during pupal stage; partially lethal - majority die; viable; short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, in adult male stages.  "
FBgn0034860	CG9812	-0.607117193	0.141954273	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9812 (FBgn0034860). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2R:23412320..23419684. It has the cytological map location 59D11. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during late larval stages, at stages throughout the pupal period.  "
FBgn0023525	CG3191	-0.607038845	0.144292658	0.999936032	NA	TTPAL;CLVS1;RLBP1;CLVS2;TTPA	moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3191 (FBgn0023525). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:2250145..2251993. It has the cytological map location 2F2. Protein features are: CRAL-TRIO lipid binding domain; CRAL/TRIO, N-terminal domain; Cellular retinaldehyde binding/alpha-tocopherol transport. Its molecular function is described by: transporter activity. It is involved in the biological process described with: transport. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0036422	CG3868	-0.606229444	0.093205268	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG3868 (FBgn0036422). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:14400769..14402725. It has the cytological map location 70D6. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed at stages throughout the larval period.
FBgn0031012	CG8051	-0.605159711	0.099949443	0.999936032	NA	SLC16A12;SLC16A6;SLC16A1	moderate;moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8051 (FBgn0031012). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:19301330..19307925. It has the cytological map location 18C1. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain. Its molecular function is described by: monocarboxylic acid transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0037435	CG18048	-0.604076929	0.150020831	0.999936032	TRMT13	TRMT13	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG18048 (FBgn0037435). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:6346111..6347519. It has the cytological map location 83E4. Protein features are: Methyltransferase TRM13; TRM13/UPF0224 family, U11-48K-like CHHC zinc finger domain; Zinc finger, CCCH-type, TRM13. Its molecular function is described by: tRNA methyltransferase activity. It is involved in the biological process described with: tRNA methylation. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during pupal stage; partially lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, during early pupal stages, in adult female stages.  "
FBgn0039487	gb	-0.603382677	0.14919006	0.999936032	NA	SLC7A7;SLC7A6;SLC7A8;SLC7A9;SLC7A5;SLC7A10;SLC7A11	moderate;moderate;moderate;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene genderblind is referred to in FlyBase by the symbol Dmel\gb (CG6070, FBgn0039487). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:27108467..27112270. It has the cytological map location 97E2. Protein features are: Amino acid/polyamine transporter I. Its molecular function is described by: L-amino acid transmembrane transporter activity; antiporter activity; amino acid transmembrane transporter activity. It is involved in the biological process described with: courtship behavior; phagocytosis; glutamate secretion; taurine transport; glutamine transport; defense response to bacterium; chemosensory behavior; amino acid transmembrane transport; male courtship behavior; L-glutamate transport. 14 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval neuromuscular junction. The phenotypic classes of alleles include: locomotor behavior defective; behavior defective; short lived; phenotype; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0032187	CG4839	-0.603220806	0.110576535	0.999936032	NA	PRKG1;PRKG2	moderate;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4839 (FBgn0032187). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:10144776..10156407. It has the cytological map location 31A3. Protein features are: AGC-kinase, C-terminal; Cyclic nucleotide-binding domain; Cyclic nucleotide-binding, conserved site; Cyclic nucleotide-binding-like; Protein kinase domain; Protein kinase-like domain; RmlC-like jelly roll fold; Serine/threonine-protein kinase, active site; cGMP-dependent protein kinase, catalytic domain. Its molecular function is described by: protein serine/threonine kinase activity; cGMP-dependent protein kinase activity; ATP binding. It is involved in the biological process described with: protein phosphorylation. 10 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0011695	EbpIII	-0.600695353	0.096856937	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Ejaculatory bulb protein III is referred to in FlyBase by the symbol Dmel\EbpIII (CG11390, FBgn0011695). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:24026172..24027518. It has the cytological map location 60B4. Protein features are: Insect odorant-binding protein A10/Ejaculatory bulb-specific protein 3. Its molecular function is unknown. It is involved in the biological process described with: response to virus; post-mating behavior; metamorphosis. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very low expression.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0039225	Ets96B	-0.600359538	0.153172651	0.999936032	NA	ETV1;ETV5;ETV4	high;moderate;moderate	DNA-binding with transcription factor activity(Ets)	NA	NA	"The gene Ets96B is referred to in FlyBase by the symbol Dmel\Ets96B (CG6892, FBgn0039225). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:24788054..24797955. It has the cytological map location 96A22. Protein features are: Ets domain; Winged helix-turn-helix DNA-binding domain. Its molecular function is described by: RNA polymerase II transcription factor activity, sequence-specific DNA binding; sequence-specific DNA binding. It is involved in the biological process described with: cell differentiation; positive regulation of circadian sleep/wake cycle, sleep; regulation of dopamine receptor signaling pathway; startle response; regulation of transcription from RNA polymerase II promoter; response to starvation. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: starvation stress response defective; viable; hyperactive; sleep defective; some die during pupal stage; lethal - all die before end of pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed at stages throughout the pupal period, in adult male stages.  "
FBgn0000422	Ddc	-0.599626546	0.124572751	0.999936032	NA	DDC;HDC	high;low	NA	NA	NA	"The gene Dopa decarboxylase is referred to in FlyBase by the symbol Dmel\Ddc (CG10697, FBgn0000422). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:19116483..19120306. It has the cytological map location 37C1. Protein features are: Aromatic-L-amino-acid decarboxylase; Pyridoxal phosphate-dependent decarboxylase; Pyridoxal phosphate-dependent transferase; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; Pyridoxal phosphate-dependent transferase, subdomain 2; Pyridoxal-phosphate binding site. Its molecular function is described by: aromatic-L-amino-acid decarboxylase activity; pyridoxal phosphate binding. It is involved in the biological process described with 15 unique terms, many of which group under: memory; behavior; reproduction; response to external stimulus; regulation of developmental process; growth; cognition; mating behavior; animal organ development; taxis; response to wounding; serotonin biosynthetic process. 146 alleles are reported. The phenotypes of these alleles manifest in: adult mesothoracic segment; eo support cell; dorsal mesothorax; pupal cuticle; wing margin; adult sense organ; mesothoracic tergum; late embryo; prepupa; axillary sclerite; mesothoracic segment; cell; embryo; prepupal integumentary system; adult cuticle. The phenotypic classes of alleles include: increased mortality; visible; phenotype; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during late larval stages.  "
FBgn0260026	CG42494	-0.598815224	0.14167444	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG42494 (FBgn0260026). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3L:3184404..3186549. It has the cytological map location 63B10. Protein features are: Chitin binding domain. Its molecular function is described by: chitin binding. It is involved in the biological process described with: chitin metabolic process. 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during early larval stages.
FBgn0021776	mira	-0.597263456	0.136104685	0.999936032	NA	SLMAP	low	NA	NA	NA	"The gene miranda is referred to in FlyBase by the symbol Dmel\mira (CG12249, FBgn0021776). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3R:19931799..19935120. It has the cytological map location 92B9. Its molecular function is described by: protein binding; myosin binding; actin binding. It is involved in the biological process described with 13 unique terms, many of which group under: cellular macromolecule localization; protein localization; asymmetric protein localization; proteolysis; protein localization to cell periphery; regulation of primary metabolic process; central nervous system development; cell division; regulation of metabolic process; regulation of embryonic pattern specification; ventral cord development. 44 alleles are reported. The phenotypes of these alleles manifest in: germ layer; abdomen; ectoderm; stage 5 embryo; ventral neurectoderm; embryonic head; non-connected developing system; tract; neuron projection bundle; ganglion mother cell; gastrula embryo; cortex associated CNS glial cell; glial cell; neurogenic region. The phenotypic classes of alleles include: fertile; lethal; visible; lethal - all die during embryonic stage; tumorigenic; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0027291	l(1)G0156	-0.596511657	0.099853443	0.999936032	NA	IDH3A	high	NA	NA	NA	"The gene lethal (1) G0156 is referred to in FlyBase by the symbol Dmel\l(1)G0156 (CG12233, FBgn0027291). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:19518428..19521810. It has the cytological map location 18C8. Protein features are: Isocitrate dehydrogenase NAD-dependent; Isocitrate/isopropylmalate dehydrogenase, conserved site; Isopropylmalate dehydrogenase-like domain. Its molecular function is described by: NAD binding; isocitrate dehydrogenase (NAD+) activity; magnesium ion binding. It is involved in the biological process described with: tricarboxylic acid cycle. 9 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: fertile; lethal; lethal - all die during pupal stage; lethal - all die during P-stage; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0038914	fit	-0.596335699	0.150070848	0.999936032	NA	NA	NA	NA	NA	NA	"The gene female-specific independent of transformer is referred to in FlyBase by the symbol Dmel\fit (CG17820, FBgn0038914). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:21883924..21884454. It has the cytological map location 93F14. Its molecular function is described by: . It is involved in the biological process described with: . 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: feeding behavior defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed in adult female stages.  "
FBgn0031663	CG8891	-0.595331924	0.12167163	0.999936032	ITPA	ITPA	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG8891 (FBgn0031663). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:4978484..4979379. It has the cytological map location 25B5. Protein features are: Ham1-like protein; Inosine triphosphate pyrophosphatase; Inosine triphosphate pyrophosphatase-like. Its molecular function is described by: nucleoside-triphosphate diphosphatase activity. It is involved in the biological process described with: neuron projection morphogenesis; nucleoside triphosphate catabolic process. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed in adult female stages.
FBgn0015904	ara	-0.593816751	0.139029194	0.999936032	NA	IRX6;IRX4;IRX3;IRX5;IRX1;IRX2	high;moderate;moderate;moderate;moderate;moderate	DNA-binding with transcription factor activity(Homeobox)	NA	NA	"The gene araucan is referred to in FlyBase by the symbol Dmel\ara (CG10571, FBgn0015904). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:12580672..12596018. It has the cytological map location 69C8-69C10. Protein features are: Homeobox KN domain; Homeobox domain; Homeobox domain-like; Homeobox, conserved site; Iroquois-class homeodomain protein; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: sequence-specific DNA binding; transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding. It is involved in the biological process described with: imaginal disc-derived wing morphogenesis; equator specification; muscle cell fate commitment; positive regulation of transcription from RNA polymerase II promoter; dendrite morphogenesis; compound eye morphogenesis; negative regulation of growth; positive regulation of transcription, DNA-templated; notum cell fate specification; imaginal disc-derived wing vein specification. 28 alleles are reported. The phenotypes of these alleles manifest in: mouthpart; postalar bristle; cell; eye disc; prepupa; dendritic tree; central nervous system; cell part; pupa; embryonic/larval brain; neuron part; optic lobe neuron. The phenotypic classes of alleles include: sterile; increased mortality during development; phenotype; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0053497	Sdic2	-0.593632855	0.11680027	0.999936032	NA	DYNC1I2;DYNC1I1	moderate;moderate	NA	NA	NA	"The gene Sperm-specific dynein intermediate chain 2 is referred to in FlyBase by the symbol Dmel\Sdic2 (CG33497, FBgn0053497). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:20181590..20186487. It has the cytological map location 19C1. Protein features are: Cytoplasmic dynein 1 intermediate chain 1/2; WD40 repeat; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: dynein heavy chain binding; dynein light chain binding; ATP-dependent microtubule motor activity, plus-end-directed. It is involved in the biological process described with: transport along microtubule; positive regulation of ATP-dependent microtubule motor activity, plus-end-directed. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed in adult male stages.  "
FBgn0086408	stl	-0.592929697	0.1462292	0.999936032	NA	ADAMTS5	moderate	NA	transmembrane protein	NA	"The gene stall is referred to in FlyBase by the symbol Dmel\stl (CG3622, FBgn0086408). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:22807860..22815993. It has the cytological map location 59B2. Protein features are: Metallopeptidase, catalytic domain; Peptidase M12B, ADAM/reprolysin; Thrombospondin type-1 (TSP1) repeat. Its molecular function is described by: zinc ion binding; metalloendopeptidase activity. It is involved in the biological process described with: oogenesis; ovarian follicle cell stalk formation; negative regulation of neuron migration; proteolysis; ovarian follicle development. 11 alleles are reported. The phenotypes of these alleles manifest in: cytoplasm; abdominal neuron; gamete; non-membrane-bounded organelle; integument of larval segment A1-7; sense organ; vitellarium; oocyte; intracellular non-membrane-bounded organelle; spectrosome; larval tagma. The phenotypic classes of alleles include: cell migration defective; female sterile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-18 embryonic stages, during late pupal stages, in adult female stages.  "
FBgn0259937	Nop60B	-0.592459118	0.106281163	0.999936032	NA	DKC1;MIR664B;TRUB1	high;moderate;moderate	NA	NA	NA	"The gene Nucleolar protein at 60B is referred to in FlyBase by the symbol Dmel\Nop60B (CG3333, FBgn0259937). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (2 unique). Gene sequence location is 2R:24174877..24186343. It has the cytological map location 60C1-60C2. Protein features are: Dyskerin-like; PUA domain; PUA-like domain; Pseudouridine synthase II, N-terminal; Pseudouridine synthase, catalytic domain; tRNA pseudouridine synthase B family; tRNA pseudouridylate synthase B, C-terminal. Its molecular function is described by: pseudouridine synthase activity; RNA binding. It is involved in the biological process described with: cellular response to starvation; box H/ACA snoRNA 3'-end processing; pseudouridine synthesis; germ cell development; rRNA processing; snRNA pseudouridine synthesis; ribosome biogenesis; wing disc development; mRNA pseudouridine synthesis; rRNA pseudouridine synthesis. 25 alleles are reported. The phenotypes of these alleles manifest in: somatic precursor cell; somatic cell of testis; egg chamber; embryo; adult thoracic sensillum; developmental compartment; male fusome; dorsal mesothorax; somatic stem cell; female reproductive system. The phenotypic classes of alleles include: sterile; increased mortality; lethal - all die before end of larval stage; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0039849	CG11334	-0.591332957	0.111451326	0.999936032	MRI1	MRI1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11334 (FBgn0039849). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:31459822..31463037. It has the cytological map location 100C4. Protein features are: Initiation factor 2B alpha/beta/delta; Initiation factor 2B-related; Methylthioribose-1-phosphate isomerase; Methylthioribose-1-phosphate isomerase-like, N-terminal domain. Its molecular function is described by: S-methyl-5-thioribose-1-phosphate isomerase activity. It is involved in the biological process described with: L-methionine salvage from methylthioadenosine; wing disc development. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: short lived; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0259721	CG42375	-0.59119115	0.135236714	0.999936032	NA	CMC2	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG42375 (FBgn0259721). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:13779624..13780795. It has the cytological map location 87F13. Protein features are: Cytochrome c oxidase biogenesis protein Cmc1-like. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0260464	CG9288	-0.59119115	0.135236714	0.999936032	NA	FAM206A	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9288 (FBgn0260464). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:13779624..13780795. It has the cytological map location 87F13. Protein features are: Glycine cleavage system H-protein/Simiate; Single hybrid motif. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0031734	CG11147	-0.590188459	0.12900026	0.999936032	NA	ABCA8	moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11147 (FBgn0031734). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:5733675..5741244. It has the cytological map location 25F4. Protein features are: AAA+ ATPase domain; ABC transporter, conserved site; ABC transporter-like; ABC-2 transporter; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: ATP binding; ATPase activity. It is involved in the biological process described with: transport. 6 alleles are reported. The phenotype of these alleles manifest in: ganglion mother cell. The phenotypic classes of alleles include: neuroanatomy defective; partially lethal - majority die; some die during pupal stage; lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 12-18 embryonic stages.  "
FBgn0014395	tilB	-0.589978495	0.160390112	0.999936032	NA	LRRC6;CEP97;LRRC46	high;low;moderate	NA	NA	NA	"The gene touch insensitive larva B is referred to in FlyBase by the symbol Dmel\tilB (CG14620, FBgn0014395). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:22449737..22451463. It has the cytological map location 20C1. Protein features are: HSP20-like chaperone; Leucine-rich repeat; Leucine-rich repeat domain, L domain-like. Its molecular function is unknown. It is involved in the biological process described with: male courtship behavior, veined wing generated song production; axoneme assembly; sensory perception of sound; temperature compensation of the circadian clock; cilium-dependent cell motility. 13 alleles are reported. The phenotypes of these alleles manifest in: Johnston organ; scolopidial cilium; adult antennal nerve; arista; cilium; spermatid axoneme. The phenotypic classes of alleles include: courtship behavior defective; locomotor behavior defective; behavior defective; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed during late larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0030882	GSS	-0.589619892	0.105001816	0.999936032	NA	GSS	high	NA	NA	NA	"The gene Glutathione Synthetase is referred to in FlyBase by the symbol Dmel\GSS (CG6835, FBgn0030882). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (5 unique). Gene sequence location is X:17889547..17898603. It has the cytological map location 16F1. Protein features are: Glutathione synthase; Glutathione synthase domain; Glutathione synthase, N-terminal, eukaryotic; Glutathione synthase, alpha-helical, eukaryotic; Glutathione synthase, substrate-binding, eukaryotic; Pre-ATP-grasp domain. Its molecular function is described by: ATP binding; glutathione synthase activity. It is involved in the biological process described with: glutathione biosynthetic process; detoxification of arsenic-containing substance; cellular response to DNA damage stimulus; response to ethanol. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, in adult male stages.  "
FBgn0052495	CG32495	-0.589619892	0.105001816	0.999936032	GSS	GSS	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32495 (FBgn0052495). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (5 unique). Gene sequence location is X:17899702..17906025. It has the cytological map location 16F1. Protein features are: Glutathione synthase; Glutathione synthase domain; Glutathione synthase, N-terminal, eukaryotic; Glutathione synthase, alpha-helical, eukaryotic; Glutathione synthase, substrate-binding, eukaryotic; Pre-ATP-grasp domain. Its molecular function is described by: glutathione synthase activity; ATP binding. It is involved in the biological process described with: detoxification of arsenic-containing substance; glutathione biosynthetic process; cellular response to DNA damage stimulus. 5 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0026415	Idgf4	-0.589537249	0.105323433	0.999936032	NA	CHIT1	moderate	NA	NA	NA	"The gene Imaginal disc growth factor 4 is referred to in FlyBase by the symbol Dmel\Idgf4 (CG1780, FBgn0026415). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is X:9927973..9930948. It has the cytological map location 9A3. Protein features are: Chitinase II; Chitinase insertion domain; Glycoside hydrolase family 18, catalytic domain; Glycoside hydrolase superfamily; Imaginal disc growth factor. Its molecular function is described by: chitinase activity; imaginal disc growth factor receptor binding; chitin binding. It is involved in the biological process described with: imaginal disc development; chitin catabolic process; wound healing; chitin-based cuticle development; ecdysis, chitin-based cuticle; carbohydrate metabolic process. 6 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval cuticle. The phenotypic classes of alleles include: fertile; viable; some die during larval stage; wound healing defective; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0085298	CG34269	-0.588861359	0.161205867	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG34269 (FBgn0085298). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:528337..528996. It has the cytological map location 61C3. Protein features are: High mobility group box domain. Its molecular function is described by: . It is involved in the biological process described with: . One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed in adult male stages.
FBgn0031897	CG13784	-0.584789233	0.111330786	0.999936032	NA	PQLC1	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13784 (FBgn0031897). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (all unique). Gene sequence location is 2L:7204538..7220033. It has the cytological map location 27E4-27E5. Protein features are: PQ-loop repeat. Its molecular function is unknown. The biological processes in which it is involved are not known. 12 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, during early pupal stages.  "
FBgn0034585	Rbpn-5	-0.58376526	0.149656375	0.999936032	NA	RABEP1;EEA1;RABEP2	high;moderate;moderate	NA	NA	NA	"The gene Rabaptin-5 is referred to in FlyBase by the symbol Dmel\Rbpn-5 (CG4030, FBgn0034585). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:21088386..21091004. It has the cytological map location 57B19. Protein features are: FYVE zinc finger; Rabaptin, GTPase-Rab5 binding domain; Zinc finger, FYVE-related; Zinc finger, FYVE/PHD-type; Zinc finger, RING-type; Zinc finger, RING-type, conserved site; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: zinc ion binding; metal ion binding; Rab GTPase binding. It is involved in the biological process described with: regulation of endosome size. 9 alleles are reported. The phenotypes of these alleles manifest in: notal microchaeta; trichogen cell; wing hair; early endosome; trichome; wing disc; wing vein. The phenotypic classes of alleles include: developmental rate defective; visible; viable; neoplasia; planar polarity defective; lethal - all die before end of P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0039042	CG13837	-0.583673328	0.102002589	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13837 (FBgn0039042). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:23043990..23044661. It has the cytological map location 94D10. Protein features are: Chitin binding domain. Its molecular function is described by: chitin binding. It is involved in the biological process described with: chitin metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0262057	Spn77Ba	-0.583241169	0.15587719	0.999936032	NA	SERPINI2;SERPINF1;SERPINI1;SERPINF2;AGT;SERPIND1;SERPINB7	low;low;low;low;low;low;low	NA	NA	NA	"The gene Serpin 77Ba is referred to in FlyBase by the symbol Dmel\Spn77Ba (CG6680, FBgn0262057). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3L:20317190..20320116. It has the cytological map location 77A1-77B9. Protein features are: Serpin domain; Serpin family. Its molecular function is described by: serine-type endopeptidase inhibitor activity. It is involved in the biological process described with: negative regulation of proteolysis; negative regulation of melanization defense response. 8 alleles are reported. The phenotypes of these alleles manifest in: trachea; pupal tracheal system; adult tracheal system; embryonic/larval tracheal system. The phenotypic classes of alleles include: lethal; increased mortality; increased mortality during development; phenotype."
FBgn0020521	pio	-0.582646923	0.149937984	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene piopio is referred to in FlyBase by the symbol Dmel\pio (CG3541, FBgn0020521). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 2R:24581245..24597862. It has the cytological map location 60D7-60D8. Protein features are: Zona pellucida domain. Its molecular function is described by: . It is involved in the biological process described with: chitin-based cuticle attachment to epithelium; apposition of dorsal and ventral imaginal disc-derived wing surfaces; open tracheal system development; chitin-based embryonic cuticle biosynthetic process. 17 alleles are reported. The phenotypes of these alleles manifest in: tracheal branch primordium; dorsal closure embryo; wing blade; cerebral branch; cell; cuticle layer; lateral trunk anterior branch; prepupa; embryonic/larval muscle system; non-connected developing system. The phenotypic classes of alleles include: some die during embryonic stage; fertile; viable; visible; lethal - all die before end of embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed at stages throughout the pupal period.  "
FBgn0037135	CG7414	-0.582111405	0.106051924	0.999936032	NA	EIF2A	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7414 (FBgn0037135). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3L:21824740..21827856. It has the cytological map location 78F3-78F4. Protein features are: Translation initiation factor 2A; Translation initiation factor, beta propellor-like domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: mRNA binding; tRNA binding; translation initiation factor activity; ribosome binding. It is involved in the biological process described with: translational initiation; regulation of translation. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0032640	Sgt	-0.58043973	0.114418202	0.999936032	SGTB	SGTB;SGTA	high;moderate	NA	NA	NA	"The gene small glutamine-rich tetratricopeptide containing protein is referred to in FlyBase by the symbol Dmel\Sgt (CG5094, FBgn0032640). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:17471603..17474773. It has the cytological map location 36C9. Protein features are: SGTA, homodimerisation domain; Tetratricopeptide repeat; Tetratricopeptide repeat 1; Tetratricopeptide repeat-containing domain; Tetratricopeptide-like helical domain. Its molecular function is described by: . It is involved in the biological process described with: negative regulation of protein oligomerization; positive regulation of chaperone-mediated protein folding. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: neurophysiology defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0000152	Axs	-0.579223899	0.164652147	0.999936032	ANO10	ANO10;ANO8	high;low	NA	transmembrane protein	NA	"The gene Abnormal X segregation is referred to in FlyBase by the symbol Dmel\Axs (CG9703, FBgn0000152). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:16680089..16683895. It has the cytological map location 15A1. Protein features are: Anoctamin. Its molecular function is unknown. It is involved in the biological process described with: meiotic spindle organization; female meiosis chromosome segregation; distributive segregation. 16 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: meiotic cell cycle defective; visible; viable; flight defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0037222	CG14642	-0.57873401	0.152818644	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14642 (FBgn0037222). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:4241045..4242717. It has the cytological map location 82A1. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 4 alleles are reported. The phenotypes of these alleles manifest in: abdominal dorsal multidendritic neuron ddaC; dendritic tree. The phenotypic classes of alleles include: neuroanatomy defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in adult male stages.  "
FBgn0263046	CG43341	-0.577983538	0.133849072	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG43341 (FBgn0263046). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:7632841..7633880. It has the cytological map location 43E6. Its molecular function is described by: . It is involved in the biological process described with: . One allele is reported. No phenotypic data is available. No phenotypic class data is available.
FBgn0034797	nahoda	-0.575792726	0.164645212	0.999936032	NA	GGN;TPRX1;GPRASP2;FRRS1	low;low;low;low	NA	transmembrane protein	NA	"The gene nahoda is referred to in FlyBase by the symbol Dmel\nahoda (CG12781, FBgn0034797). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2R:22896174..22916719. It has the cytological map location 59B4. Protein features are: Cellulose/chitin-binding protein, N-terminal; DOMON domain; EGF-like domain; EGF-like domain, extracellular; EGF-like, conserved site; SEA domain. Its molecular function is described by: . It is involved in the biological process described with: . 8 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages.  "
FBgn0015919	caup	-0.575741452	0.157903619	0.999936032	NA	IRX6;IRX4;IRX3;IRX5;IRX1;IRX2	moderate;moderate;moderate;moderate;moderate;moderate	DNA-binding with transcription factor activity(Homeobox)	NA	NA	"The gene caupolican is referred to in FlyBase by the symbol Dmel\caup (CG10605, FBgn0015919). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:12609631..12621798. It has the cytological map location 69D1. Protein features are: Homeobox KN domain; Homeobox domain; Homeobox domain-like; Homeobox, conserved site; Iroquois-class homeodomain protein. Its molecular function is described by: transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; transcription factor activity, sequence-specific DNA binding; sequence-specific DNA binding. It is involved in the biological process described with: positive regulation of transcription from RNA polymerase II promoter; regulation of mitotic cell cycle; compound eye morphogenesis; equator specification; muscle cell fate commitment; imaginal disc-derived wing vein specification; negative regulation of growth; phagocytosis. 23 alleles are reported. The phenotypes of these alleles manifest in: pupa; neuron; larva; wing blade; photoreceptor cell; larval mesothoracic segment; mesothoracic suture; segmental subdivision of integument; larval thoracic segment; eye photoreceptor cell. The phenotypic classes of alleles include: phenotype; male sterile; cell death defective; sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 06-18 hour embryonic stages.  "
FBgn0265959	rdgC	-0.57481344	0.097469432	0.999936032	NA	PPEF2;PPEF1	high;moderate	NA	NA	NA	"The gene retinal degeneration C is referred to in FlyBase by the symbol Dmel\rdgC (CG44746, FBgn0265959). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3L:20248080..20265554. It has the cytological map location 77A4-77B1. Protein features are: Calcineurin-like phosphoesterase domain, ApaH type; EF-Hand 1, calcium-binding site; EF-hand domain; EF-hand domain pair; IQ motif, EF-hand binding site; Metallo-dependent phosphatase-like; Serine/threonine-protein phosphatase with EF-hands; Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase. Its molecular function is described by: iron ion binding; protein serine/threonine phosphatase activity; manganese ion binding; calcium-dependent protein serine/threonine phosphatase activity; calmodulin binding; calcium ion binding. It is involved in the biological process described with: thermotaxis; deactivation of rhodopsin mediated signaling; calcium-mediated signaling; phototransduction; detection of temperature stimulus involved in sensory perception of pain; protein dephosphorylation. 16 alleles are reported. The phenotypes of these alleles manifest in: rhabdomere R1; rhabdomere R6; retina; photoreceptor cell; rhabdomere R2; rhabdomere; rhabdomere R3; ommatidium; rhabdomere R5; rhabdomere R4. The phenotypic classes of alleles include: stress response defective; temperature response defective; phenotype; visible; heat stress response defective."
FBgn0003390	shf	-0.573888197	0.154388264	0.999936032	NA	WIF1	high	NA	NA	NA	"The gene shifted is referred to in FlyBase by the symbol Dmel\shf (CG3135, FBgn0003390). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is X:6771463..6779659. It has the cytological map location 6C13-6D1. Protein features are: EGF-like domain; EGF-like, conserved site; WIF domain; Wnt inhibitory factor (WIF)-1. Its molecular function is described by: protein binding. It is involved in the biological process described with: protein stabilization; positive regulation of smoothened signaling pathway; smoothened signaling pathway; regulation of smoothened signaling pathway; synaptic target recognition. 21 alleles are reported. The phenotypes of these alleles manifest in: head bristle; wing basal cell; ommatidium; anatomical cluster; metathoracic leg; wing vein L3; embryonic/larval integumentary system; larva; denticle belt; peripheral nervous system. The phenotypic classes of alleles include: phenotype; lethal - all die before end of embryonic stage; visible; increased mortality; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed at stages throughout the pupal period.  "
FBgn0036899	tey	-0.573004376	0.172414703	0.999936032	NA	RNF220	low	NA	NA	NA	"The gene teyrha-meyrha is referred to in FlyBase by the symbol Dmel\tey (CG8780, FBgn0036899). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 3L:19650506..19664104. It has the cytological map location 76B11-76C1. Protein features are: E3 ubiquitin-protein ligase RNF220, middle domain. Its molecular function is unknown. It is involved in the biological process described with: negative regulation of transcription, DNA-templated; synaptic target recognition; protein ubiquitination; positive regulation of canonical Wnt signaling pathway. 7 alleles are reported. The phenotypes of these alleles manifest in: distal costal vein; wing vein; costal cell; A1-7 ventral longitudinal muscle 1; medial costal vein; eye; abdominal segment motor neuron. The phenotypic classes of alleles include: lethal; viable; visible; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 06-24 hour embryonic stages, during early larval stages.  "
FBgn0026439	Eaat1	-0.572569297	0.122369986	0.999936032	NA	SLC1A3;SLC1A6;SLC1A1;SLC1A4;SLC1A5;SLC1A7;SLC1A2	high;moderate;moderate;moderate;moderate;moderate;low	NA	transmembrane protein	NA	"The gene Excitatory amino acid transporter 1 is referred to in FlyBase by the symbol Dmel\Eaat1 (CG3747, FBgn0026439). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2L:9333567..9341925. It has the cytological map location 30A8. Protein features are: Sodium:dicarboxylate symporter; Sodium:dicarboxylate symporter, conserved site. Its molecular function is described by: L-aspartate transmembrane transporter activity; L-glutamate transmembrane transporter activity; glutamate:sodium symporter activity. It is involved in the biological process described with: aspartate transport; larval locomotory behavior; determination of adult lifespan; L-glutamate transport; regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction; chemical synaptic transmission. 17 alleles are reported. The phenotypes of these alleles manifest in: dopaminergic neuron; neuropil; neuromuscular junction; reticular neuropil associated glial cell; adult neuromuscular junction; synapse; aCC neuron; RP2 motor neuron. The phenotypic classes of alleles include: behavior defective; increased mortality; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late pupal stages.  "
FBgn0030884	CG6847	-0.571667061	0.171024102	0.999936032	PNLIPRP3	PNLIP;PNLIPRP3;PLA1A;PNLIPRP1;PNLIPRP2;LIPI;LIPH	moderate;low;moderate;low;low;low;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6847 (FBgn0030884). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:17911462..17924163. It has the cytological map location 16F3. Protein features are: Alpha/Beta hydrolase fold; Lipase, N-terminal; Lipase/vitellogenin; Triacylglycerol lipase family. Its molecular function is described by: carboxylic ester hydrolase activity; lipase activity. It is involved in the biological process described with: lipid catabolic process. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages.  "
FBgn0020618	Rack1	-0.571659381	0.110812607	0.999936032	GNB2L1	RACK1	high	NA	NA	NA	"The gene Receptor of activated protein kinase C 1 is referred to in FlyBase by the symbol Dmel\Rack1 (CG7111, FBgn0020618). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 2L:7825347..7827315. It has the cytological map location 28D1. Protein features are: G-protein beta WD-40 repeat; WD40 repeat; WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. It is involved in the biological process described with 14 unique terms, many of which group under: reproductive process; cap-independent translational initiation; sexual reproduction; positive regulation of viral process; mRNA metabolic process; cellular protein complex assembly; cell communication; macromolecule modification; regulation of carbohydrate biosynthetic process; locomotory behavior; autophagy. 18 alleles are reported. The phenotypes of these alleles manifest in: glycogen granule; egg; oocyte; embryonic/larval fat body; autophagosome; trichogen cell; ovary. The phenotypic classes of alleles include: lethal; increased mortality; lethal - all die before end of prepupal stage; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, in adult female stages.  "
FBgn0015380	drl	-0.571302784	0.166605598	0.999936032	NA	RYK	moderate	NA	transmembrane protein	NA	"The gene derailed is referred to in FlyBase by the symbol Dmel\drl (CG17348, FBgn0015380). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:19190342..19208621. It has the cytological map location 37C7. Protein features are: Protein kinase domain; Protein kinase-like domain; Serine-threonine/tyrosine-protein kinase, catalytic domain; Tyrosine-protein kinase, active site; WIF domain. Its molecular function is described by: Wnt-protein binding; protein kinase binding; protein homodimerization activity; Wnt-activated receptor activity; ATP binding; protein heterodimerization activity. It is involved in the biological process described with 18 unique terms, many of which group under: phosphorylation; imaginal disc development; cellular component biogenesis; olfactory behavior; regulation of cellular carbohydrate metabolic process; regulation of response to stimulus; glucose metabolic process; cellular protein metabolic process; haltere disc development; neuron recognition; gland development; negative chemotaxis; regulation of signaling. 50 alleles are reported. The phenotypes of these alleles manifest in: cell projection; abdominal segment 6; connective; eo-type sensillum; larval abdominal segment 1; neuron part; adult olfactory receptor neuron; mushroom body pedunculus; chaeta; ventral nervous system. The phenotypic classes of alleles include: behavior defective; phenotype; fertile; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 06-18 hour embryonic stages.  "
FBgn0028490	CG31705	-0.571004478	0.144631472	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31705 (FBgn0028490). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:11523021..11528205. It has the cytological map location 32F2. Protein features are: Protein of unknown function DUF4813. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0020508	Ag5r2	-0.569983748	0.112082917	0.999936032	NA	PI15;R3HDML;CLEC18C;CRISPLD2;CRISPLD1;CLEC18B;CLEC18A;GLIPR1L1	moderate;moderate;low;low;low;low;low;low	NA	NA	NA	"The gene Antigen 5-related 2 is referred to in FlyBase by the symbol Dmel\Ag5r2 (CG9540, FBgn0020508). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:14782962..14784052. It has the cytological map location 12F4. Protein features are: CAP domain; Cysteine-rich  secretory protein, allergen V5/Tpx-1-related; Venom allergen 3, insect; Ves allergen. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal - all die during P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of extremely low expression.  Peak expression observed during late larval stages.  "
FBgn0020912	Ptx1	-0.569435505	0.129398783	0.999936032	PITX2	PITX2;PITX3;PITX1	high;moderate;moderate	DNA-binding with transcription factor activity(Homeobox)	NA	NA	"The gene Ptx1 is referred to in FlyBase by the symbol Dmel\Ptx1 (CG1447, FBgn0020912). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3R:30912754..30930682. It has the cytological map location 100A7-100B1. Protein features are: Homeobox domain; Homeobox domain-like; Homeobox, conserved site; OAR domain. Its molecular function is described by: sequence-specific DNA binding; transcription factor activity, sequence-specific DNA binding. It is involved in the biological process described with: dendrite morphogenesis; regulation of transcription from RNA polymerase II promoter. 9 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages.  "
FBgn0264721	CR43989	-0.569081501	0.175173403	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR43989 (FBgn0264721). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3L:11163849..11164801. It has the cytological map location 68A9. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0030067	Rbm13	-0.568449921	0.141424247	0.999936032	NA	MAK16	high	NA	NA	NA	"The gene RNA-binding motif protein 13 is referred to in FlyBase by the symbol Dmel\Rbm13 (CG10648, FBgn0030067). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:8901699..8903761. It has the cytological map location 8B7. Protein features are: Mak16 protein; Ribosomal L28e/Mak16. Its molecular function is unknown. It is involved in the biological process described with: maturation of LSU-rRNA; maturation of 5.8S rRNA; positive regulation of multicellular organism growth. 2 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; embryonic/larval neuroblast. The phenotypic classes of alleles include: lethal - all die during pupal stage; lethal; viable; neuroanatomy defective; small body. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0038391	GATAe	-0.56825322	0.117066084	0.999936032	NA	GATA4;GATA5;GATA6;GATA3;GATA1;GATA2;TRPS1	moderate;moderate;low;low;low;low;low	DNA-binding with transcription factor activity(GATA)	NA	NA	"The gene GATAe is referred to in FlyBase by the symbol Dmel\GATAe (CG10278, FBgn0038391). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:16009105..16019133. It has the cytological map location 89A12. Protein features are: Armadillo-like helical; WD40/YVTN repeat-like-containing domain; Zinc finger, GATA-type; Zinc finger, NHR/GATA-type. Its molecular function is described by: RNA polymerase II transcription factor binding; chromatin binding; zinc ion binding; RNA polymerase II transcription factor activity, sequence-specific DNA binding; transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding; RNA polymerase II regulatory region sequence-specific DNA binding. It is involved in the biological process described with: negative regulation of gene expression; enteroendocrine cell differentiation; enterocyte differentiation; antimicrobial humoral response; endoderm development; midgut development; positive regulation of transcription from RNA polymerase II promoter; intestinal stem cell homeostasis. 9 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; enteroendocrine cell of posterior adult midgut epithelium; enterocyte of posterior adult midgut epithelium; adult posterior midgut epithelium; intestinal stem cell of posterior adult midgut epithelium. The phenotypic classes of alleles include: size defective; viable; visible; lethal - all die before end of first instar larval stage; short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages.  "
FBgn0022959	yps	-0.568143359	0.119378954	0.999936032	NA	YBX3;YBX1;YBX2	high;moderate;moderate	DNA-binding with transcription factor activity	NA	NA	"The gene ypsilon schachtel is referred to in FlyBase by the symbol Dmel\yps (CG5654, FBgn0022959). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:12121274..12125150. It has the cytological map location 68F4. Protein features are: Cold shock domain; Cold-shock conserved site; Cold-shock protein, DNA-binding; Nucleic acid-binding, OB-fold. Its molecular function is described by: mRNA binding; DNA binding. It is involved in the biological process described with: oogenesis; regulation of transcription, DNA-templated; mRNA splicing, via spliceosome. 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: flight defective; viable; lethal; fertile; female fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0031148	Cbs	-0.567780722	0.128656033	0.999936032	CBS;LOC102724560	CBS;CBSL	high;moderate	NA	NA	NA	"The gene Cystathionine ‘_-synthase is referred to in FlyBase by the symbol Dmel\Cbs (CG1753, FBgn0031148). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is X:21045138..21049096. It has the cytological map location 19E7. Protein features are: CBS domain; Cystathionine beta-synthase; Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site; Tryptophan synthase beta subunit-like PLP-dependent enzyme. Its molecular function is described by: pyridoxal phosphate binding; cystathionine beta-synthase activity. It is involved in the biological process described with: response to endoplasmic reticulum stress; cysteine biosynthetic process from serine; determination of adult lifespan; cysteine biosynthetic process via cystathionine. 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; short lived; viable; long lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed during early larval stages.  "
FBgn0036876	CG9451	-0.56768637	0.176778868	0.999936032	NA	ACPT;ACP2;ACPP;ACP6	moderate;moderate;moderate;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9451 (FBgn0036876). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:19498197..19500798. It has the cytological map location 76B5. Protein features are: Histidine acid phosphatase active site; Histidine phosphatase superfamily; Histidine phosphatase superfamily, clade-2; Venom acid phosphatase Acph-1. Its molecular function is described by: acid phosphatase activity. It is involved in the biological process described with: dephosphorylation. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during early larval stages, in adult male stages.  "
FBgn0029176	eEF1gamma	-0.564153498	0.114288469	0.999936032	NA	EEF1G	high	NA	NA	NA	"The gene eukaryotic translation elongation factor 1 gamma is referred to in FlyBase by the symbol Dmel\eEF1‘_ (CG11901, FBgn0029176). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:29220172..29222109. It has the cytological map location 99A1. Protein features are: Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Thioredoxin-like fold; Translation elongation factor EF1B, gamma chain, conserved. Its molecular function is described by: glutathione transferase activity; translation elongation factor activity. It is involved in the biological process described with: glutathione metabolic process; autophagic cell death; salivary gland cell autophagic cell death; translational elongation. 14 alleles are reported. The phenotypes of these alleles manifest in: wing blade posterior compartment; ommatidium; sarcomere; scutellar bristle; eye; Z disc. The phenotypic classes of alleles include: lethal - all die before end of larval stage; increased mortality; phenotype; some die during larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed within 00-12 hour embryonic stages, during early larval stages.  "
FBgn0037543	CG10903	-0.563663512	0.143505125	0.999936032	WBSCR22	WBSCR22;WBSCR27	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10903 (FBgn0037543). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:8030411..8032145. It has the cytological map location 84E9. Protein features are: S-adenosyl-L-methionine-dependent methyltransferase; Uncharacterised protein family, methyltransferase, Williams-Beuren syndrome. Its molecular function is described by: rRNA (guanine) methyltransferase activity. It is involved in the biological process described with: rRNA (guanine-N7)-methylation. 4 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; ganglion mother cell; mesothoracic tergum. The phenotypic classes of alleles include: neuroanatomy defective; viable; lethal - all die during P-stage; visible; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages.  "
FBgn0040942	CG12643	-0.563593745	0.123575432	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG12643 (FBgn0040942). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:10264233..10265263. It has the cytological map location 9B5. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal; some die during pupal stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed at stages throughout the pupal period.
FBgn0038017	CG4115	-0.562775319	0.166888043	0.999936032	NA	SELL;CLEC3A;CLEC3B	low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4115 (FBgn0038017). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:12360008..12363255. It has the cytological map location 87B8. Protein features are: C-type lectin fold; C-type lectin, conserved site; C-type lectin-like; C-type lectin-like/link domain. Its molecular function is described by: carbohydrate binding. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period.  "
FBgn0038056	CG5961	-0.562710321	0.132748285	0.999936032	FBXO9	FBXO9	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5961 (FBgn0038056). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:12458421..12460294. It has the cytological map location 87B11. Protein features are: F-box domain; MIT; Tetratricopeptide repeat-containing domain. Its molecular function is described by: ubiquitin-protein transferase activity. It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. 8 alleles are reported. The phenotypes of these alleles manifest in: interommatidial bristle; eye; ommatidium. The phenotypic classes of alleles include: short lived; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0031636	CG12194	-0.562185773	0.136387434	0.999936032	NA	MFSD1	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12194 (FBgn0031636). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:4838347..4841465. It has the cytological map location 25A8. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain. Its molecular function is unknown. It is involved in the biological process described with: transmembrane transport. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, during early larval stages, in adult male stages.  "
FBgn0027610	Dic1	-0.561935727	0.12163839	0.999936032	NA	SLC25A10;SLC25A11;SLC25A14;SLC25A30;MRPL12	high;low;low;low;low	NA	NA	NA	"The gene Dicarboxylate carrier 1 is referred to in FlyBase by the symbol Dmel\Dic1 (CG8790, FBgn0027610). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:13364938..13369278. It has the cytological map location 87E8. Protein features are: Mitochondrial carrier domain; Mitochondrial substrate/solute carrier. Its molecular function is described by: malate transmembrane transporter activity; antiporter activity; thiosulfate transmembrane transporter activity; succinate transmembrane transporter activity; oxaloacetate transmembrane transporter activity; inorganic phosphate transmembrane transporter activity; sulfate transmembrane transporter activity; phosphate transmembrane transporter activity. It is involved in the biological process described with: thiosulfate transport; sulfate transport; mitochondrial transport; succinate transmembrane transport; phosphate ion transmembrane transport; malate transmembrane transport; oxaloacetate transport. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed during early larval stages.  "
FBgn0036975	CG5618	-0.560826809	0.127976327	0.999936032	NA	GADL1;CSAD;GAD2	moderate;moderate;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5618 (FBgn0036975). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:20353449..20356632. It has the cytological map location 77B5. Protein features are: Pyridoxal phosphate-dependent decarboxylase; Pyridoxal phosphate-dependent transferase; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; Pyridoxal phosphate-dependent transferase, subdomain 2. Its molecular function is described by: carboxy-lyase activity; pyridoxal phosphate binding. It is involved in the biological process described with: carboxylic acid metabolic process. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during early pupal stages.  "
FBgn0026592	Fie	-0.560662308	0.173588776	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene Fire exit is referred to in FlyBase by the symbol Dmel\Fie (CG1079, FBgn0026592). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:3892574..3894833. It has the cytological map location 63F5. Protein features are: Protein of unknown function DUF4728. Its molecular function is described by: . It is involved in the biological process described with: detection of temperature stimulus involved in sensory perception of pain; negative regulation of dendrite morphogenesis. 20 alleles are reported. The phenotypes of these alleles manifest in: dorsal multidendritic neuron ddaC; tarsal segment; eye; trichome; dendrite. The phenotypic classes of alleles include: visible; phenotype; lethal - all die before end of second instar larval stage; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed in adult male stages.  "
FBgn0015777	nrv2	-0.560469552	0.174478932	0.999936032	NA	ATP1B1;ATP1B4;ATP1B2;ATP1B3;ATP4B	moderate;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene nervana 2 is referred to in FlyBase by the symbol Dmel\nrv2 (CG9261, FBgn0015777). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (2 unique). Gene sequence location is 2L:6789770..6798862. It has the cytological map location 27B1-27B2. Protein features are: Sodium/potassium-transporting ATPase subunit beta. Its molecular function is described by: sodium:potassium-exchanging ATPase activity; cation transmembrane transporter activity. It is involved in the biological process described with 11 unique terms, many of which group under: cation transport; transport; ion transport; localization; establishment of blood-brain barrier; sensory perception of mechanical stimulus; establishment of localization; potassium ion transport; cell-cell junction organization; heart morphogenesis. 28 alleles are reported. The phenotypes of these alleles manifest in: late embryo; non-connected developing system; tracheal branch primordium; somatic cell; external sensory organ; apical junction complex; early extended germ band embryo; ganglionic branch primordium; mechanosensory sensory organ; cell-cell junction; syncytium; embryonic foregut; external sensillum. The phenotypic classes of alleles include: auditory perception defective; neuroanatomy defective; lethal; short lived; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 06-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0032077	CG9515	-0.56030031	0.154615628	0.999936032	NA	ASMTL;ASMT	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9515 (FBgn0032077). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:8941945..8943257. It has the cytological map location 29F5. Protein features are: Inosine triphosphate pyrophosphatase-like; Maf-like protein. Its molecular function is described by: nucleoside-triphosphate diphosphatase activity. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed at stages throughout the larval period.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0028990	Spn27A	-0.560296595	0.147643719	0.999936032	NA	SERPINI2;SERPINF1;SERPINI1;SERPINF2;AGT;SERPIND1;SERPINB7;SERPINA3	low;low;low;low;low;low;low;low	NA	NA	NA	"The gene Serpin 27A is referred to in FlyBase by the symbol Dmel\Spn27A (CG11331, FBgn0028990). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:6671065..6673347. It has the cytological map location 26F6. Protein features are: Serpin domain; Serpin family; Serpin, conserved site. Its molecular function is described by: enzyme inhibitor activity; serine-type endopeptidase inhibitor activity. It is involved in the biological process described with 11 unique terms, many of which group under: response to stimulus; multicellular organismal process; phenol-containing compound metabolic process; response to external biotic stimulus; cell communication; behavior; axis specification; immune system process; adult behavior; defense response to fungus; response to wounding; anatomical structure development. 19 alleles are reported. The phenotypes of these alleles manifest in: embryonic/first instar larval cuticle; trachea; wing; embryonic/larval hemolymph; melanotic mass. The phenotypic classes of alleles include: lethal - all die before end of P-stage; visible; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed at stages throughout the pupal period.  "
FBgn0002567	Rab32	-0.559282525	0.127651362	0.999936032	NA	RAB32;RAB38;RAB29	high;moderate;moderate	NA	NA	NA	"The gene Rab32 is referred to in FlyBase by the symbol Dmel\Rab32 (CG8024, FBgn0002567). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (5 unique). Gene sequence location is 2R:9177864..9186342. It has the cytological map location 45B2-45B3. Protein features are: P-loop containing nucleoside triphosphate hydrolase; Ras-related protein Rab29/Rab38/Rab32; Small GTP-binding protein domain; Small GTPase superfamily. Its molecular function is described by: GTP binding; protein binding; GTPase activity. It is involved in the biological process described with 13 unique terms, many of which group under: establishment of localization; ocellus pigment metabolic process; regulation of catabolic process; regulation of lipid localization; transport; cognition; neurological system process; system process; multicellular organismal process; developmental pigmentation. 25 alleles are reported. The phenotypes of these alleles manifest in: primary pigment cell pigment granule; Malpighian tubule; secondary pigment cell pigment granule; ocellus pigment granule; dopaminergic PPM1 neuron; dopaminergic PPL1 neuron; tertiary pigment cell pigment granule; pigment cell. The phenotypic classes of alleles include: fertile; memory defective; viable; eye color defective; visible; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, during late pupal stages.  "
FBgn0085484	Pdxk	-0.558230666	0.11835922	0.999936032	NA	PDXK;LOC105372824	high;moderate	NA	NA	NA	"The gene Pyridoxal kinase is referred to in FlyBase by the symbol Dmel\Pdxk (CG34455, FBgn0085484). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:9360316..9362042. It has the cytological map location 67B2. Protein features are: Pyridoxamine kinase/Phosphomethylpyrimidine kinase; Pyridoxine kinase; Ribokinase-like. Its molecular function is described by: pyridoxal kinase activity. It is involved in the biological process described with: cellular response to monosaccharide stimulus; pyridoxal 5'-phosphate salvage. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; DNA repair defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed during early pupal stages.  "
FBgn0026314	Ugt35b	-0.55757637	0.152076482	0.999936032	NA	UGT2A3;UGT2B15;UGT2B10;UGT2B17;UGT1A3;UGT2B28;UGT2B4;UGT2A2;UGT2B11;UGT2B7;UGT8;UGT1A1;UGT3A1;UGT3A2;UGT1A4;UGT1A10;UGT1A7;UGT1A5;UGT1A9;UGT1A6;UGT1A8	high;high;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene UDP-glycosyltransferase 35b is referred to in FlyBase by the symbol Dmel\Ugt35b (CG6649, FBgn0026314). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:11168503..11170246. It has the cytological map location 86D5. Protein features are: UDP-glucuronosyl/UDP-glucosyltransferase; UDP-glycosyltransferase family, conserved site. Its molecular function is described by: glucuronosyltransferase activity; UDP-glycosyltransferase activity. It is involved in the biological process described with: UDP-glucose metabolic process. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed in adult male stages.  "
FBgn0034406	Jheh3	-0.557524211	0.118737572	0.999936032	NA	EPHX1	moderate	NA	transmembrane protein	NA	"The gene Juvenile hormone epoxide hydrolase 3 is referred to in FlyBase by the symbol Dmel\Jheh3 (CG15106, FBgn0034406). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:18860375..18862078. It has the cytological map location 55F8. Protein features are: Alpha/Beta hydrolase fold; Epoxide hydrolase; Epoxide hydrolase, N-terminal; Epoxide hydrolase-like. Its molecular function is described by: cis-stilbene-oxide hydrolase activity. The biological processes in which it is involved are not known. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0033633	Smyd4-3	-0.556393938	0.18405774	0.999936032	NA	SMYD4;SMYD1;SMYD3	high;low;low	NA	NA	NA	"The gene SET and MYND domain containing, class 4, member 3 is referred to in FlyBase by the symbol Dmel\Smyd4-3 (CG7759, FBgn0033633). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:11405597..11408079. It has the cytological map location 47F10. Protein features are: SET domain; Tetratricopeptide repeat; Tetratricopeptide-like helical domain; Zinc finger, MYND-type. Its molecular function is described by: histone deacetylase binding. It is involved in the biological process described with: negative regulation of gene expression; compound eye photoreceptor development. 4 alleles are reported. The phenotypes of these alleles manifest in: interommatidial bristle; ommatidium. The phenotypic classes of alleles include: partially lethal - majority live; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 06-18 hour embryonic stages, during late pupal stages.  "
FBgn0014427	CG11899	-0.55597582	0.127367959	0.999936032	NA	PSAT1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11899 (FBgn0014427). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:29200454..29201770. It has the cytological map location 99A1. Protein features are: Aminotransferase class V domain; Aminotransferase class-V, pyridoxal-phosphate binding site; Phosphoserine aminotransferase; Pyridoxal phosphate-dependent transferase; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; Pyridoxal phosphate-dependent transferase, subdomain 2. Its molecular function is described by: O-phospho-L-serine:2-oxoglutarate aminotransferase activity. It is involved in the biological process described with: L-serine biosynthetic process. 3 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late larval stages, at stages throughout the pupal period.  "
FBgn0052191	CG32191	-0.555917137	0.121520524	0.999936032	NA	ARSI;ARSJ;ARSB;ARSE;ARSA	high;moderate;moderate;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32191 (FBgn0052191). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:17806451..17809146. It has the cytological map location 75A2. Protein features are: Alkaline phosphatase-like, alpha/beta/alpha; Alkaline-phosphatase-like, core domain; Sulfatase, N-terminal; Sulfatase, conserved site. Its molecular function is described by: sulfuric ester hydrolase activity. It is involved in the biological process described with: metabolic process. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0022770	Peritrophin-A	-0.555650086	0.185878026	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Peritrophin A is referred to in FlyBase by the symbol Dmel\Peritrophin-A (CG17058, FBgn0022770). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:20244647..20248203. It has the cytological map location 19C1. Protein features are: Chitin binding domain. Its molecular function is described by: chitin binding. It is involved in the biological process described with: chitin metabolic process; multicellular organism reproduction. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages, at stages throughout the larval period, during late pupal stages.  "
FBgn0016926	Pino	-0.554285205	0.13139807	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Pinocchio is referred to in FlyBase by the symbol Dmel\Pino (CG4710, FBgn0016926). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:1114654..1128953. It has the cytological map location 21F1. Its molecular function is unknown. It is involved in the biological process described with: olfactory behavior. 28 alleles are reported. The phenotype of these alleles manifest in: antenna. The phenotypic classes of alleles include: flightless; fertile; viable; neurophysiology defective; smell perception defective; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed during late larval stages, at stages throughout the pupal period.  "
FBgn0034605	CG15661	-0.553521463	0.180234672	0.999936032	UGT2B11	UGT1A1;UGT1A3;UGT2B10;UGT2B11;UGT2B4;UGT2B15;UGT2B28;UGT2A2;UGT2B17;UGT2A3;UGT2B7;UGT3A1;UGT8;UGT3A2;UGT1A4;UGT1A10;UGT1A7;UGT1A5;UGT1A9;UGT1A6;UGT1A8	high;moderate;moderate;moderate;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15661 (FBgn0034605). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:21215435..21217779. It has the cytological map location 57D2. Protein features are: UDP-glucuronosyl/UDP-glucosyltransferase; UDP-glycosyltransferase family, conserved site. Its molecular function is described by: glucuronosyltransferase activity. It is involved in the biological process described with: metabolic process. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed within 06-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0015288	RpL22	-0.553003033	0.120808541	0.999936032	NA	RPL22;RPL22L1	high;moderate	NA	NA	NA	"The gene Ribosomal protein L22 is referred to in FlyBase by the symbol Dmel\RpL22 (CG7434, FBgn0015288). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:762560..765130. It has the cytological map location 1C4. Protein features are: Ribosomal protein L22e. Its molecular function is described by: structural constituent of ribosome; RNA binding. It is involved in the biological process described with: translation; positive regulation of multicellular organism growth; cytoplasmic translation. 8 alleles are reported. The phenotype of these alleles manifest in: class IV dendritic arborizing neuron. The phenotypic classes of alleles include: neuroanatomy defective; small body; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages.  "
FBgn0004364	18w	-0.552664393	0.187553657	0.999936032	NA	CHADL	high	NA	transmembrane protein	NA	"The gene 18 wheeler is referred to in FlyBase by the symbol Dmel\18w (CG8896, FBgn0004364). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:20111511..20116932. It has the cytological map location 56F8. Protein features are: Cysteine-rich flanking region, C-terminal; Leucine-rich repeat; Leucine-rich repeat domain, L domain-like; Leucine-rich repeat, typical subtype; Toll/interleukin-1 receptor homology (TIR) domain. Its molecular function is described by: transmembrane signaling receptor activity. It is involved in the biological process described with 13 unique terms, many of which group under: defense response; cellular response to stimulus; cell adhesion; antimicrobial humoral response; ovarian follicle cell migration; developmental growth; epithelial cell migration; axis elongation; antibacterial humoral response; biological adhesion. 27 alleles are reported. The phenotypes of these alleles manifest in: dorsal appendage; abdomen; wing; egg; chorion; portion of tissue; haltere; sensory system neuron; chemosensory system; adult abdomen; compound cell cluster organ; olfactory system neuron; chorionic specialization. The phenotypic classes of alleles include: lethal - all die during embryonic stage; some die during larval stage; cell migration defective; increased mortality; body color defective; some die during P-stage; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0031491	alpha4GT1	-0.552321241	0.165508633	0.999936032	A4GALT	A4GALT;A4GNT	high;moderate	NA	transmembrane protein	NA	"The gene ‘±4GT1 is referred to in FlyBase by the symbol Dmel\‘±4GT1 (CG17223, FBgn0031491). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:3021309..3023141. It has the cytological map location 23C4. Protein features are: Alpha 1,4-glycosyltransferase domain; Glycosyltransferase, DXD sugar-binding motif; Nucleotide-diphospho-sugar transferases. Its molecular function is described by: alpha-1,4-N-acetylgalactosaminyltransferase activity; acetylgalactosaminyltransferase activity. It is involved in the biological process described with: glycosphingolipid biosynthetic process; glycolipid biosynthetic process; positive regulation of Notch signaling pathway; negative regulation of apoptotic process. 16 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0037563	CG11672	-0.552241756	0.121310846	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11672 (FBgn0037563). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:8289395..8290578. It has the cytological map location 84F9. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, in adult male stages.  "
FBgn0052702	Cubn	-0.551701242	0.180418983	0.999936032	NA	CUBN;TLL1;ASTL;BMP1;TLL2;MEP1B;MEP1A	high;low;low;low;low;low;low	NA	NA	NA	"The gene Cubilin is referred to in FlyBase by the symbol Dmel\Cubn (CG32702, FBgn0052702). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:9558665..9571308. It has the cytological map location 8E7-8E10. Protein features are: CUB domain; EGF-like calcium-binding domain; EGF-like calcium-binding, conserved site; EGF-like domain; EGF-like, conserved site; EGF-type aspartate/asparagine hydroxylation site; Growth factor receptor cysteine-rich domain. Its molecular function is described by: calcium ion binding. It is involved in the biological process described with: nephrocyte filtration; renal protein absorption. 3 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval pericardial cell. The phenotypic classes of alleles include: chemical sensitive; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages.  "
FBgn0010423	TpnC47D	-0.550984671	0.149347194	0.999936032	NA	CALM1;CALML3;CALML4;CABP4;CALM3;CABP5;CALM2;CALML5;CABP7;CABP1;CABP2;CALN1;CALML6;CALB1	moderate;moderate;low;moderate;low;moderate;low;low;moderate;moderate;moderate;moderate;moderate;low	NA	NA	NA	"The gene Troponin C at 47D is referred to in FlyBase by the symbol Dmel\TpnC47D (CG9073, FBgn0010423). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:11273845..11275286. It has the cytological map location 47E5. Protein features are: EF-Hand 1, calcium-binding site; EF-hand domain; EF-hand domain pair. Its molecular function is described by: calcium ion binding. The biological processes in which it is involved are not known. 4 alleles are reported. The phenotypes of these alleles manifest in: sarcomere; Z disc. The phenotypic classes of alleles include: lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very low expression.  Peak expression observed during early larval stages.  "
FBgn0030999	Mur18B	-0.550583195	0.18947084	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene Mucin related 18B is referred to in FlyBase by the symbol Dmel\Mur18B (CG7874, FBgn0030999). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:19213254..19214938. It has the cytological map location 18B1. Protein features are: Chitin binding domain. Its molecular function is described by: extracellular matrix structural constituent; chitin binding. It is involved in the biological process described with: chitin metabolic process. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0260722	CR42549	-0.550307906	0.136816705	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CR42549 (FBgn0260722). It is a non_protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts. Gene sequence location is 3R:9548104..9551806. It has the cytological map location 85D23-85D24. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, during early pupal stages.  "
FBgn0041342	Pcyt1	-0.549235774	0.129983187	0.999936032	NA	PCYT1A;PCYT1B	high;moderate	NA	NA	NA	"The gene Phosphocholine cytidylyltransferase 1 is referred to in FlyBase by the symbol Dmel\Pcyt1 (CG1049, FBgn0041342). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (1 unique). Gene sequence location is 3L:1546092..1553504. It has the cytological map location 62A3-62A5. Protein features are: Cytidyltransferase-like domain; Rossmann-like alpha/beta/alpha sandwich fold. Its molecular function is described by: choline-phosphate cytidylyltransferase activity. It is involved in the biological process described with: determination of adult lifespan; eye development; phosphatidylcholine biosynthetic process; imaginal disc-derived wing morphogenesis; oogenesis; endocytosis; establishment of ommatidial planar polarity; biosynthetic process. 42 alleles are reported. The phenotypes of these alleles manifest in: cytoplasmic part; germline cyst; intracellular; adult external thorax; non-membrane-bounded organelle; membrane part; dorsal appendage; egg; adipose system; adult thorax; oocyte; nurse cell spectrosome; rhabdomere; whole membrane. The phenotypic classes of alleles include: lethal; increased mortality during development; phenotype; wild-type. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 12-18 embryonic stages, in stages of adults of both sexes.  "
FBgn0032684	CG10178	-0.549176317	0.153973028	0.999936032	UGT1A1	UGT2B10;UGT1A3;UGT1A1;UGT2B4;UGT2B15;UGT2A2;UGT2B17;UGT2B11;UGT2A3;UGT2B7;UGT8;UGT2B28;UGT3A1;UGT3A2;UGT1A4;UGT1A10;UGT1A7;UGT1A5;UGT1A9;UGT1A6;UGT1A8	moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10178 (FBgn0032684). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:18509560..18513512. It has the cytological map location 36F6. Protein features are: UDP-glucuronosyl/UDP-glucosyltransferase; UDP-glycosyltransferase family, conserved site. Its molecular function is described by: glucuronosyltransferase activity. It is involved in the biological process described with: metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: short lived; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during late larval stages.  "
FBgn0265498	CR44367	-0.549170466	0.185565227	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44367 (FBgn0265498). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2R:13854659..13855894. It has the cytological map location 50C6. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0028949	CG15254	-0.549005005	0.126638753	0.999936032	NA	BMP1;CUBN;TLL1;MEP1B;MEP1A;ASTL;TLL2	moderate;low;low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15254 (FBgn0028949). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:15613905..15614828. It has the cytological map location 35D3. Protein features are: Astacin-like metallopeptidase domain; Metallopeptidase, catalytic domain; Peptidase M12A; Peptidase, metallopeptidase. Its molecular function is described by: zinc ion binding; metalloendopeptidase activity. It is involved in the biological process described with: proteolysis; sensory perception of pain. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: pain response defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0000477	DNaseII	-0.548810989	0.172549378	0.999936032	NA	DNASE2B;DNASE2	high;high	NA	NA	NA	"The gene Deoxyribonuclease II is referred to in FlyBase by the symbol Dmel\DNaseII (CG7780, FBgn0000477). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:18019375..18021161. It has the cytological map location 90E1. Protein features are: Deoxyribonuclease II. Its molecular function is described by: endodeoxyribonuclease activity; deoxyribonuclease II activity. It is involved in the biological process described with: sleep; DNA catabolic process; nurse cell apoptotic process; apoptotic DNA fragmentation. 13 alleles are reported. The phenotypes of these alleles manifest in: egg chamber; ovary; nucleus; nurse cell. The phenotypic classes of alleles include: viable; cell death defective; semi-fertile; electrophoretic variant; increased cell death. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period.  "
FBgn0031689	Cyp28d1	-0.548672838	0.124662954	0.999936032	NA	TBXAS1;CYP3A43;CYP3A4;CYP3A5;CYP3A7-CYP3A51P	moderate;low;low;low;low	NA	transmembrane protein	NA	"The gene Cyp28d1 is referred to in FlyBase by the symbol Dmel\Cyp28d1 (CG10833, FBgn0031689). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:5210460..5212445. It has the cytological map location 25C10. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Its molecular function is described by: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; iron ion binding; heme binding; oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0039453	CG6403	-0.548651388	0.135995532	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6403 (FBgn0039453). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:26735417..26736307. It has the cytological map location 97D1. Protein features are: Chitin binding domain. Its molecular function is described by: chitin binding. It is involved in the biological process described with: chitin metabolic process. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0052694	CG32694	-0.548352672	0.181643795	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG32694 (FBgn0052694). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (6 unique). Gene sequence location is X:9989690..10006882. It has the cytological map location 9A4. Its molecular function is unknown. The biological processes in which it is involved are not known. 8 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: flightless; lethal; viable; visible; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages.
FBgn0034748	CG17807	-0.54809752	0.164139196	0.999936032	ALKBH8	ALKBH8;KIAA1456	high;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17807 (FBgn0034748). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:22634019..22635942. It has the cytological map location 58F2. Protein features are: ALKBH8, RNA recognition motif; Alkylated DNA repair protein alkB homologue 8; Alpha-ketoglutarate-dependent dioxygenase AlkB-like; Methyltransferase type 11; Oxoglutarate/iron-dependent dioxygenase; RNA recognition motif domain; S-adenosyl-L-methionine-dependent methyltransferase. Its molecular function is described by: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; ferrous iron binding; tRNA binding; tRNA (uracil) methyltransferase activity. It is involved in the biological process described with: tRNA methylation; oxidation-reduction process; tRNA wobble uridine modification. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0020910	RpL3	-0.547870397	0.123102161	0.999936032	NA	RPL3;RPL3L	high;moderate	NA	NA	NA	"The gene Ribosomal protein L3 is referred to in FlyBase by the symbol Dmel\RpL3 (CG4863, FBgn0020910). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 3R:11221894..11225173. It has the cytological map location 86D8. Protein features are: Ribosomal protein L3; Ribosomal protein L3, conserved site; Translation protein, beta-barrel domain. Its molecular function is described by: RNA binding; structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; translation; ribosomal large subunit assembly. 8 alleles are reported. The phenotypes of these alleles manifest in: sarcomere; Z disc; embryonic/larval somatic muscle. The phenotypic classes of alleles include: viable; lethal; partially lethal; pain response defective; some die during larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0015268	Nap1	-0.547109301	0.125523835	0.999936032	NAP1L1	NAP1L1;NAP1L4;NAP1L2;NAP1L3;NAP1L5	high;moderate;moderate;moderate;moderate	NA	NA	NA	"The gene Nucleosome assembly protein 1 is referred to in FlyBase by the symbol Dmel\Nap1 (CG5330, FBgn0015268). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:23905175..23907294. It has the cytological map location 60A9. Protein features are: Nucleosome assembly protein (NAP). Its molecular function is described by: histone binding. It is involved in the biological process described with: chromatin remodeling; sperm chromatin decondensation; telomere maintenance; sperm chromatin condensation; regulation of transcription, DNA-templated; nucleosome assembly. 29 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; eye; investment cone; mesothoracic tergum. The phenotypic classes of alleles include: partially lethal; increased mortality during development; phenotype; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in stages of adults of both sexes.  "
FBgn0053481	dpr7	-0.547025154	0.16585152	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene defective proboscis extension response 7 is referred to in FlyBase by the symbol Dmel\dpr7 (CG33481, FBgn0053481). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 4:247124..253329. It has the cytological map location 102B1. Protein features are: Immunoglobulin V-set domain; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold. Its molecular function is described by: . It is involved in the biological process described with: synapse organization; sensory perception of chemical stimulus. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during late pupal stages.  "
FBgn0046689	Takl1	-0.546164385	0.146915294	0.999936032	NA	MAP3K7;MLKL	moderate;moderate	NA	NA	NA	"The gene Tak1-like 1 is referred to in FlyBase by the symbol Dmel\Takl1 (CG31421, FBgn0046689). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:20770828..20772601. It has the cytological map location 92F13. Protein features are: Mitogen-activated protein (MAP) kinase kinase kinase 7; Protein kinase domain; Protein kinase, ATP binding site; Protein kinase-like domain; Serine-threonine/tyrosine-protein kinase, catalytic domain; Serine/threonine-protein kinase, active site. Its molecular function is described by: magnesium ion binding; signal transducer activity; ATP binding; protein kinase activity; MAP kinase kinase kinase activity. It is involved in the biological process described with: intracellular signal transduction; protein phosphorylation. 8 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0030883	CG7772	-0.545501929	0.18634835	0.999936032	MTFP1	MTFP1	high	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG7772 (FBgn0030883). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:17906031..17907261. It has the cytological map location 16F1. Protein features are: Mitochondrial 18kDa protein. Its molecular function is described by: . It is involved in the biological process described with: mitochondrial fission. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile; locomotor behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed in adult male stages.
FBgn0040398	CG14629	-0.545001937	0.126266501	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14629 (FBgn0040398). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:1051525..1052631. It has the cytological map location 1E1. Protein features are: Protein of unknown function DUF1397. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; lethal - all die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0032774	CG17549	-0.544778791	0.134668982	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17549 (FBgn0032774). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (2 unique). Gene sequence location is 2L:19387050..19390075. It has the cytological map location 37D4. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. The phenotypes of these alleles manifest in: chaeta; mesothoracic tergum. The phenotypic classes of alleles include: fertile; viable; lethal - all die during P-stage; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during late larval stages, in adult male stages.  "
FBgn0035779	CG8562	-0.54475673	0.124385805	0.999936032	NA	CPA2;CPA5;CPA4;CPA1;CPB1;CPO;CPA3;CPB2;CPA6	moderate;moderate;moderate;moderate;moderate;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8562 (FBgn0035779). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:7398285..7399912. It has the cytological map location 65F11. Protein features are: Carboxypeptidase, activation peptide; Insect gut carboxypeptidase-like, carboxypeptidase domain; Peptidase M14, carboxypeptidase A; Protease propeptides/proteinase inhibitor I9. Its molecular function is described by: metallocarboxypeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0029131	Debcl	-0.544319535	0.16459511	0.999936032	NA	BOK	moderate	Maybe TF	transmembrane protein	NA	"The gene Death executioner Bcl-2 is referred to in FlyBase by the symbol Dmel\Debcl (CG33134, FBgn0029131). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:6648654..6652842. It has the cytological map location 42B2-42C1. Protein features are: Bcl-2-related ovarian killer protein; Bcl2-like; Blc2 family. Its molecular function is described by: protein heterodimerization activity; protein homodimerization activity. It is involved in the biological process described with 14 unique terms, many of which group under: apoptotic signaling pathway; cellular response to external stimulus; developmental process involved in reproduction; regulation of mitochondrial membrane permeability; response to radiation; positive regulation of macroautophagy; negative regulation of neuron apoptotic process; regulation of catabolic process; response to external stimulus; response to abiotic stimulus; organelle organization. 25 alleles are reported. The phenotypes of these alleles manifest in: central nervous system; embryonic/larval imaginal precursor; imaginal precursor; genitalia; sternite; female reproductive system; melanotic mass; adult external head; developing material anatomical entity; pigment cell; maxillary segment; adult thoracic sensillum; circulatory system; embryonic/larval sensillum; embryonic/larval glial cell; eye photoreceptor cell. The phenotypic classes of alleles include: increased mortality during development; phenotype; increased mortality; cell death defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0032897	CG9336	-0.543780502	0.155403983	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9336 (FBgn0032897). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:20858695..20861014. It has the cytological map location 38F3. Its molecular function is described by: . It is involved in the biological process described with: . 8 alleles are reported. The phenotypes of these alleles manifest in: wing; mesothoracic tergum. The phenotypic classes of alleles include: body color defective; stress response defective; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0033649	pyr	-0.543458772	0.18891972	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene pyramus is referred to in FlyBase by the symbol Dmel\pyr (CG13194, FBgn0033649). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:11712263..11726345. It has the cytological map location 48C2. Protein features are: Cytokine IL1/FGF; Fibroblast growth factor family. Its molecular function is described by: growth factor activity; fibroblast growth factor receptor binding. It is involved in the biological process described with 11 unique terms, many of which group under: urogenital system development; fibroblast growth factor receptor signaling pathway; regulation of multicellular organismal process; larval somatic muscle development; anatomical structure morphogenesis; tissue development; positive regulation of cell development; response to organic substance; formation of primary germ layer; positive regulation of cellular process; renal filtration cell differentiation; muscle cell migration; embryo development; single organism signaling; visceral muscle development. 16 alleles are reported. The phenotypes of these alleles manifest in: longitudinal visceral muscle primordium; dorsal vessel primordium; organ system subdivision; embryonic somatic muscle; A1-7 ventral oblique muscle 4; reticular neuropil associated glial cell; A2-7 ventral oblique muscle 6; central nervous system; gastrula embryo; visceral muscle; embryonic dorsal vessel; ventral oblique muscle 6. The phenotypic classes of alleles include: phenotype; increased mortality during development; lethal; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult male stages.  "
FBgn0085353	CG34324	-0.542502519	0.125727999	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG34324 (FBgn0085353). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:13456534..13457663. It has the cytological map location 11F8. Protein features are: Chitin binding domain. Its molecular function is described by: chitin binding. It is involved in the biological process described with: chitin metabolic process. 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of no expression detected.  Peak expression observed in adult male stages.
FBgn0011224	heph	-0.541839234	0.184766661	0.999936032	NA	PTBP1;PTBP2;PTBP3	high;moderate;moderate	NA	NA	NA	"The gene hephaestus is referred to in FlyBase by the symbol Dmel\heph (CG31000, FBgn0011224). It is a protein_coding_gene from Drosophila melanogaster. It has 25 annotated transcripts and 25 polypeptides (10 unique). Gene sequence location is 3R:31846987..32015520. It has the cytological map location 100D3-100E2. Protein features are: HnRNP-L/PTB; Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2; RNA recognition motif domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: translation repressor activity, nucleic acid binding; mRNA 3'-UTR binding; mRNA binding. It is involved in the biological process described with: imaginal disc-derived wing margin morphogenesis; imaginal disc-derived wing vein morphogenesis; sperm individualization; spermatid development; negative regulation of oskar mRNA translation; mRNA processing; oocyte microtubule cytoskeleton polarization. 127 alleles are reported. The phenotypes of these alleles manifest in: embryo; germline cyst; sensory organ cell; cuticular specialization; spermatid; cuticle; macrochaeta; head; individualization stage spermatid; male germline cell. The phenotypic classes of alleles include: female fertile; visible; phenotype; fertile; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, during early pupal stages.  "
FBgn0039678	Obp99a	-0.541594063	0.196592238	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Odorant-binding protein 99a is referred to in FlyBase by the symbol Dmel\Obp99a (CG18111, FBgn0039678). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:29671657..29672334. It has the cytological map location 99B7. Protein features are: Pheromone/general odorant binding protein. Its molecular function is described by: odorant binding. It is involved in the biological process described with: sensory perception of chemical stimulus; olfactory behavior; response to pheromone; sensory perception of smell. 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of moderately high expression.  Peak expression observed within 06-18 hour embryonic stages.  "
FBgn0037727	CG8358	-0.541330829	0.130381013	0.999936032	NA	KEL;ECE2;ECE1;ECEL1	high;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8358 (FBgn0037727). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:9675523..9677778. It has the cytological map location 85E3. Protein features are: Metallopeptidase, catalytic domain; Neprilysin-21; Peptidase M13; Peptidase M13, C-terminal domain; Peptidase M13, N-terminal domain. Its molecular function is described by: metalloendopeptidase activity. It is involved in the biological process described with: proteolysis. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed during early pupal stages.  "
FBgn0037328	RpL35A	-0.540335299	0.128855133	0.999936032	NA	RPL35A	high	NA	NA	NA	"The gene Ribosomal protein L35A is referred to in FlyBase by the symbol Dmel\RpL35A (CG2099, FBgn0037328). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:5465630..5467101. It has the cytological map location 83A4. Protein features are: Ribosomal protein L35A; Ribosomal protein L35Ae, conserved site; Translation protein, beta-barrel domain. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; positive regulation of peptide hormone secretion; positive regulation of multicellular organism growth; ribosomal large subunit biogenesis; translation. 4 alleles are reported. The phenotypes of these alleles manifest in: sarcomere; embryonic/larval somatic muscle; Z disc. The phenotypic classes of alleles include: small body; lethal - all die during larval stage; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0040253	Ugt86Dg	-0.540234025	0.15471883	0.999936032	NA	UGT1A3;UGT2B10;UGT2A3;UGT2B7;UGT1A1;UGT2B4;UGT2B15;UGT2A2;UGT2B17;UGT2B11;UGT8;UGT1A6;UGT2B28;UGT3A1;UGT3A2;UGT1A4;UGT1A10;UGT1A7;UGT1A5;UGT1A9;UGT1A8	high;moderate;moderate;high;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene Ugt86Dg is referred to in FlyBase by the symbol Dmel\Ugt86Dg (CG17200, FBgn0040253). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:11164423..11166074. It has the cytological map location 86D5. Protein features are: UDP-glucuronosyl/UDP-glucosyltransferase; UDP-glycosyltransferase family, conserved site. Its molecular function is described by: glucuronosyltransferase activity. It is involved in the biological process described with: metabolic process. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed during early larval stages.  "
FBgn0031634	Ir25a	-0.539695919	0.135888257	0.999936032	NA	GRID2	high	NA	transmembrane protein	NA	"The gene Ionotropic receptor 25a is referred to in FlyBase by the symbol Dmel\Ir25a (CG15627, FBgn0031634). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 2L:4830846..4835300. It has the cytological map location 25A8. Protein features are: Ionotropic glutamate receptor; Ionotropic glutamate receptor, L-glutamate and glycine-binding domain; Ionotropic glutamate receptor, metazoa; Periplasmic binding protein-like I. Its molecular function is described by: ionotropic glutamate receptor activity; ligand-gated ion channel activity; olfactory receptor activity; extracellular-glutamate-gated ion channel activity; coreceptor activity. It is involved in the biological process described with: entrainment of circadian clock; detection of chemical stimulus involved in sensory perception; transmission of nerve impulse; detection of chemical stimulus involved in sensory perception of smell; temperature compensation of the circadian clock; ion transport. 12 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable; neurophysiology defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed within 06-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.  "
FBgn0037730	CG9444	-0.539659135	0.16727687	0.999936032	NA	SLC15A2;SLC15A1;SLC15A3	moderate;moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9444 (FBgn0037730). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:9681415..9684264. It has the cytological map location 85E4. Protein features are: Major facilitator superfamily domain; PTR2 family proton/oligopeptide symporter, conserved site; Proton-dependent oligopeptide transporter family. Its molecular function is described by: transporter activity. It is involved in the biological process described with: oligopeptide transport. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during early pupal stages.  "
FBgn0260775	DnaJ-60	-0.538891962	0.164016586	0.999936032	NA	DNAJC4	high	NA	transmembrane protein	NA	"The gene DnaJ-like-60 is referred to in FlyBase by the symbol Dmel\DnaJ-60 (CG42567, FBgn0260775). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:24157668..24159312. It has the cytological map location 60C1. Protein features are: DnaJ domain. Its molecular function is described by: unfolded protein binding. It is involved in the biological process described with: spermatogenesis; protein folding. 6 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed during early larval stages, during late pupal stages, in adult male stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0036211	CG5946	-0.538024342	0.141972752	0.999936032	CYB5R2	CYB5R2;CYB5R3;CYB5R1;OXNAD1	high;moderate;moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5946 (FBgn0036211). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (6 unique). Gene sequence location is 3L:11816695..11822275. It has the cytological map location 68E1. Protein features are: Ferredoxin reductase-type FAD-binding domain; Flavoprotein pyridine nucleotide cytochrome reductase; NADH:cytochrome b5 reductase (CBR); Oxidoreductase FAD/NAD(P)-binding; Oxidoreductase, FAD-binding domain; Riboflavin synthase-like beta-barrel. Its molecular function is described by: oxidoreductase activity. It is involved in the biological process described with: phagocytosis; regulation of lipid storage; retrograde vesicle-mediated transport, Golgi to ER; inter-male aggressive behavior; oxidation-reduction process. 16 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval hemocyte; trichogen cell. The phenotypic classes of alleles include: viable; visible; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed during early larval stages.  "
FBgn0052284	CG32284	-0.537827751	0.146826375	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG32284 (FBgn0052284). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:3186664..3187245. It has the cytological map location 63B10. Protein features are: Chitin binding domain. Its molecular function is described by: chitin binding. It is involved in the biological process described with: chitin metabolic process. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed during late larval stages.
FBgn0043792	CG30427	-0.536997518	0.195899425	0.999936032	NA	FAR2;FAR1	moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG30427 (FBgn0043792). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (3 unique). Gene sequence location is 2R:24928747..24937477. It has the cytological map location 60E5. Protein features are: Fatty acyl-CoA reductase; Fatty acyl-CoA reductase, C-terminal; Male sterility, NAD-binding; NAD(P)-binding domain. Its molecular function is described by: fatty-acyl-CoA reductase (alcohol-forming) activity. It is involved in the biological process described with: long-chain fatty-acyl-CoA metabolic process; phagocytosis; wax biosynthetic process; determination of adult lifespan. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; long lived; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages.  "
FBgn0011284	RpS4	-0.536230457	0.130481264	0.999936032	NA	RPS4X;RPS4Y1;RPS4Y2	high;moderate;moderate	NA	NA	NA	"The gene Ribosomal protein S4 is referred to in FlyBase by the symbol Dmel\RpS4 (CG11276, FBgn0011284). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3L:13041756..13044234. It has the cytological map location 69F6. Protein features are: 40S ribosomal protein S4, C-terminal domain; KOW; RNA-binding S4 domain; Ribosomal protein S4e; Ribosomal protein S4e, N-terminal; Ribosomal protein S4e, N-terminal, conserved site; Ribosomal protein S4e, central region. Its molecular function is described by: structural constituent of ribosome; RNA binding. It is involved in the biological process described with: cytoplasmic translation; translation. 7 alleles are reported. The phenotypes of these alleles manifest in: sarcomere; Z disc; embryonic/larval somatic muscle. The phenotypic classes of alleles include: some die during pupal stage; partially lethal; lethal - all die before end of pupal stage; lethal - all die during larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages.  "
FBgn0038306	Art3	-0.53595574	0.178319207	0.999936032	PRMT3	PRMT3;PRMT8;PRMT1	high;low;low	NA	NA	NA	"The gene Arginine methyltransferase 3 is referred to in FlyBase by the symbol Dmel\Art3 (CG6563, FBgn0038306). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:15227605..15229408. It has the cytological map location 88E3. Protein features are: Protein arginine N-methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase; Zinc finger C2H2-type. Its molecular function is described by: nucleic acid binding; histone-arginine N-methyltransferase activity; protein-arginine omega-N asymmetric methyltransferase activity. It is involved in the biological process described with: peptidyl-arginine methylation; regulation of transcription, DNA-templated. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed during early larval stages.  "
FBgn0261560	Thor	-0.535338689	0.131111225	0.999936032	NA	EIF4EBP2;EIF4EBP1;EIF4EBP3	high;moderate;moderate	NA	NA	NA	"The gene Thor is referred to in FlyBase by the symbol Dmel\Thor (CG8846, FBgn0261560). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:3478434..3479612. It has the cytological map location 23F3-23F6. Protein features are: Eukaryotic translation initiation factor 4E binding. Its molecular function is described by: eukaryotic initiation factor 4E binding. It is involved in the biological process described with 14 unique terms, many of which group under: response to stimulus; immune system process; immune response; single-organism process; regulation of cellular component size; syncytium formation by plasma membrane fusion; response to bacterium; determination of adult lifespan; regulation of cell growth; lipid metabolic process. 30 alleles are reported. The phenotypes of these alleles manifest in: embryo; abdominal adult fat mass; cell projection part; imaginal precursor; adult sense organ; embryonic/larval imaginal precursor; presynapse; developing embryonic structure; appendage; presumptive embryonic/larval system; A1-7 dorsal acute muscle 1; neuron part. The phenotypic classes of alleles include: behavior defective; chemical resistant; phenotype; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in stages of adults of both sexes.  "
FBgn0029827	CG6048	-0.534591723	0.143906588	0.999936032	NA	HABP2;KLK14;KLK10;AZU1;CFD;PRSS55	low;low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6048 (FBgn0029827). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:5952565..5954046. It has the cytological map location 5C10. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: regulation of terminal button organization; proteolysis. 7 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, in stages of adults of both sexes.  "
FBgn0022709	Adk1	-0.534228431	0.147678643	0.999936032	NA	AK1;AK5;CMPK1	high;moderate;low	NA	NA	NA	"The gene Adenylate kinase 1 is referred to in FlyBase by the symbol Dmel\Adk1 (CG17146, FBgn0022709). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:12200322..12204082. It has the cytological map location 69A2. Protein features are: Adenylate kinase, conserved site; Adenylate kinase, isozyme 1/5; Adenylate kinase/UMP-CMP kinase; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: ATP binding; adenylate kinase activity; uridylate kinase activity. It is involved in the biological process described with: 'de novo' pyrimidine nucleobase biosynthetic process; nucleobase-containing compound metabolic process; ATP metabolic process. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0039308	CG11889	-0.534104479	0.158223933	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11889 (FBgn0039308). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:25270209..25273267. It has the cytological map location 96C8. Protein features are: CHK kinase-like; Protein kinase-like domain; Protein of unknown function DUF227. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, in adult male stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0000559	eEF2	-0.533464065	0.131401586	0.999936032	NA	EEF2;EFTUD2	high;low	NA	NA	NA	"The gene eukaryotic translation elongation factor 2 is referred to in FlyBase by the symbol Dmel\eEF2 (CG2238, FBgn0000559). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:21677913..21682164. It has the cytological map location 39E7. Protein features are: EF-G domain III/V-like; Elongation factor EFG, domain V-like; P-loop containing nucleoside triphosphate hydrolase; Ribosomal protein S5 domain 2-type fold; Ribosomal protein S5 domain 2-type fold, subgroup; Small GTP-binding protein domain; Tr-type G domain, conserved site; Transcription factor, GTP-binding domain; Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFTu-like, domain 2; Translation protein, beta-barrel domain. Its molecular function is described by: GTPase activity; GTP binding; translation elongation factor activity. It is involved in the biological process described with: translational elongation. 8 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages.  "
FBgn0032285	CG17108	-0.532666799	0.186614345	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17108 (FBgn0032285). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:10692940..10694103. It has the cytological map location 32A4. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: some die during pupal stage; partially lethal - majority die; visible; viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages, in stages of adults of both sexes.  "
FBgn0044823	Spec2	-0.532588372	0.198591855	0.999936032	NA	CDC42SE2;CDC42SE1	high;moderate	NA	NA	NA	"The gene Spec2 is referred to in FlyBase by the symbol Dmel\Spec2 (CG14672, FBgn0044823). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:5616644..5624125. It has the cytological map location 83B6. Protein features are: CRIB domain. Its molecular function is described by: Rho GTPase binding; structural molecule activity. It is involved in the biological process described with: signal transduction; regulation of Rho protein signal transduction; regulation of signal transduction. 20 alleles are reported. The phenotype of these alleles manifest in: germline cell. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0261445	sgl	-0.532223997	0.140568206	0.999936032	NA	UGDH	high	NA	NA	NA	"The gene sugarless is referred to in FlyBase by the symbol Dmel\sgl (CG10072, FBgn0261445). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:6959554..6964758. It has the cytological map location 65D4-65D5. Protein features are: 6-phosphogluconate dehydrogenase C-terminal domain-like; NAD(P)-binding domain; UDP-glucose 6-dehydrogenase, eukaryotic type; UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase, C-terminal; UDP-glucose/GDP-mannose dehydrogenase, N-terminal; UDP-glucose/GDP-mannose dehydrogenase, dimerisation. Its molecular function is described by: NAD binding; UDP-glucose 6-dehydrogenase activity. It is involved in the biological process described with 17 unique terms, many of which group under: biological regulation; cell communication; carbohydrate biosynthetic process; aggressive behavior; behavior; regulation of biological process; cell surface receptor signaling pathway; morphogenesis of an epithelium; cell migration involved in gastrulation; single-organism behavior; multi-organism behavior; nervous system development. 42 alleles are reported. The phenotypes of these alleles manifest in: synapse; trichome field; midgut constriction; thorax; early extended germ band embryo; macrochaeta; integumentary system; imaginal disc; neuron; midgut primordium. The phenotypic classes of alleles include: increased mortality; increased mortality during development; phenotype; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, during early pupal stages.  "
FBgn0032783	CG10237	-0.531963293	0.155847109	0.999936032	NA	TTPAL;CLVS2	high;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10237 (FBgn0032783). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is 2L:19435850..19442727. It has the cytological map location 37E1. Protein features are: CRAL-TRIO lipid binding domain; CRAL/TRIO, N-terminal domain; Cellular retinaldehyde binding/alpha-tocopherol transport. Its molecular function is described by: transporter activity. It is involved in the biological process described with: transport. 7 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period.  "
FBgn0039882	CG11576	-0.530882156	0.138366566	0.999936032	SLC52A3	SLC52A3;SLC52A2;SLC52A1	high;moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11576 (FBgn0039882). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:31806867..31810186. It has the cytological map location 100D2. Protein features are: Solute carrier family 52, riboflavin transporter. Its molecular function is described by: riboflavin transporter activity. It is involved in the biological process described with: riboflavin transport. 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal; fertile; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, during early larval stages, during early pupal stages, in stages of adults of both sexes.  "
FBgn0263380	CR43432	-0.529145375	0.193193557	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR43432 (FBgn0263380). It is a non_protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts. Gene sequence location is 3L:14976626..14977631. It has the cytological map location 71A4. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0259977	Tdc1	-0.528724979	0.179722443	0.999936032	NA	DDC;HDC	moderate;low	NA	NA	NA	"The gene Tyrosine decarboxylase 1 is referred to in FlyBase by the symbol Dmel\Tdc1 (CG30445, FBgn0259977). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:6677001..6680391. It has the cytological map location 42C4. Protein features are: Aromatic-L-amino-acid decarboxylase; Pyridoxal phosphate-dependent decarboxylase; Pyridoxal phosphate-dependent transferase; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; Pyridoxal phosphate-dependent transferase, subdomain 2; Pyridoxal-phosphate binding site. Its molecular function is described by: carboxy-lyase activity; tyrosine decarboxylase activity; pyridoxal phosphate binding. It is involved in the biological process described with: cellular amino acid metabolic process; behavioral response to ethanol. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; chemical sensitive; hypoactive. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages.  "
FBgn0038603	PKD	-0.528416057	0.201102828	0.999936032	PRKD3	PRKD3;PRKD1;PRKD2	high;high;moderate	NA	NA	NA	"The gene Protein Kinase D is referred to in FlyBase by the symbol Dmel\PKD (CG7125, FBgn0038603). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (3 unique). Gene sequence location is 3R:18303279..18314407. It has the cytological map location 91A2. Protein features are: Diacylglycerol/phorbol-ester binding; PH domain-like; Pleckstrin homology domain; Protein kinase C mu-related; Protein kinase C-like, phorbol ester/diacylglycerol-binding domain; Protein kinase domain; Protein kinase, ATP binding site; Protein kinase-like domain; Serine/threonine-protein kinase, active site. Its molecular function is described by: ATP binding; protein serine/threonine kinase activity; protein kinase C activity. It is involved in the biological process described with: protein phosphorylation; protein kinase D signaling; regulation of glucose metabolic process. 9 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 06-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0032946	nrv3	-0.527523739	0.152856775	0.999936032	ATP1B1	ATP1B1;ATP1B2;ATP1B3;ATP1B4;ATP4B	high;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene nervana 3 is referred to in FlyBase by the symbol Dmel\nrv3 (CG8663, FBgn0032946). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 2L:21380000..21393319. It has the cytological map location 39D2. Protein features are: Sodium/potassium-transporting ATPase subunit beta. Its molecular function is unknown. It is involved in the biological process described with: sensory perception of sound; response to auditory stimulus; sodium ion transport; potassium ion transport. 15 alleles are reported. The phenotypes of these alleles manifest in: eye; eye photoreceptor cell; rhabdomere of eye photoreceptor cell; mitochondrion; ommatidium. The phenotypic classes of alleles include: increased mortality; stress response defective; phenotype; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during late pupal stages, in adult male stages.  "
FBgn0037562	CG11671	-0.526538891	0.139004498	0.999936032	NA	C19orf12	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11671 (FBgn0037562). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:8287876..8288613. It has the cytological map location 84F8. Protein features are: Protein C19orf12 homologue. Its molecular function is unknown. It is involved in the biological process described with: neuromuscular process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed during late larval stages, in stages of adults of both sexes.  "
FBgn0038258	CG7362	-0.526367105	0.163903841	0.999936032	NA	PKM;PKLR	moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7362 (FBgn0038258). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:14751748..14754460. It has the cytological map location 88D2. Protein features are: Pyruvate kinase; Pyruvate kinase, C-terminal; Pyruvate kinase, active site; Pyruvate kinase, barrel; Pyruvate/Phosphoenolpyruvate kinase-like domain. Its molecular function is described by: magnesium ion binding; potassium ion binding; pyruvate kinase activity. It is involved in the biological process described with: phagocytosis; glycolytic process. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed at stages throughout the pupal period, in adult male stages.  "
FBgn0052283	Drsl3	-0.526367105	0.163903841	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene Drosomycin-like 3 is referred to in FlyBase by the symbol Dmel\Drsl3 (CG32283, FBgn0052283). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:3314996..3315355. It has the cytological map location 63D1. Protein features are: Knottin, scorpion toxin-like. Its molecular function is described by: . It is involved in the biological process described with: defense response to fungus. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal; some die during pupal stage; pain response defective; partially lethal - majority die; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed at stages throughout the pupal period.  "
FBgn0035473	mge	-0.526011779	0.143847066	0.999936032	NA	TOMM22	high	NA	transmembrane protein	NA	"The gene maggie is referred to in FlyBase by the symbol Dmel\mge (CG14981, FBgn0035473). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3L:3907852..3909931. It has the cytological map location 63F6. Protein features are: Mitochondrial import receptor subunit Tom22. Its molecular function is described by: P-P-bond-hydrolysis-driven protein transmembrane transporter activity; protein channel activity. It is involved in the biological process described with: protein import into mitochondrial outer membrane; protein import into mitochondrial matrix. 11 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during larval stage; hypoactive; lethal; lethal - all die before end of larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 06-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.  "
FBgn0027930	MP1	-0.525929925	0.192447807	0.999936032	NA	NA	NA	Maybe TF	NA	NA	"The gene Melanization Protease 1 is referred to in FlyBase by the symbol Dmel\MP1 (CG1102, FBgn0027930). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3R:4307908..4309835. It has the cytological map location 82A3. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Proteinase, regulatory CLIP domain; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: endopeptidase activity; serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; melanization defense response; response to fungus. 7 alleles are reported. The phenotype of these alleles manifest in: melanotic mass. The phenotypic classes of alleles include: lethal; increased mortality; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 12-18 embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0038912	CG6656	-0.524613998	0.211150313	0.999936032	NA	ACPT;ACP2;ACPP;ACP6	moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6656 (FBgn0038912). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:21875293..21877788. It has the cytological map location 93F14. Protein features are: Histidine phosphatase superfamily; Histidine phosphatase superfamily, clade-2. Its molecular function is described by: acid phosphatase activity. It is involved in the biological process described with: dephosphorylation. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0022359	Sodh-2	-0.523860633	0.212603374	0.999936032	SORD	SORD	high	NA	NA	NA	"The gene Sorbitol dehydrogenase-2 is referred to in FlyBase by the symbol Dmel\Sodh-2 (CG4649, FBgn0022359). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:10876384..10878257. It has the cytological map location 86C7. Protein features are: Alcohol dehydrogenase, C-terminal; Alcohol dehydrogenase, N-terminal; Alcohol dehydrogenase, zinc-type, conserved site; GroES-like; NAD(P)-binding domain; Polyketide synthase, enoylreductase domain. Its molecular function is described by: oxidoreductase activity; zinc ion binding. It is involved in the biological process described with: oxidation-reduction process. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed at stages throughout the larval period.  "
FBgn0033917	SmydA-1	-0.523381878	0.212884248	0.999936032	NA	SMYD3;SMYD1	moderate;low	NA	NA	NA	"The gene SET and MYND domain containing, arthropod-specific, member 1 is referred to in FlyBase by the symbol Dmel\SmydA-1 (CG8503, FBgn0033917). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:14243778..14246066. It has the cytological map location 50E5-50E6. Protein features are: Zinc finger, MYND-type. Its molecular function is described by: zinc ion binding; histone deacetylase binding. It is involved in the biological process described with: negative regulation of gene expression. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed during late pupal stages.  "
FBgn0037270	eIF3f1	-0.523351586	0.142632837	0.999936032	NA	EIF3F	high	NA	NA	NA	"The gene eukaryotic translation initiation factor 3 subunit f1 is referred to in FlyBase by the symbol Dmel\eIF3f1 (CG9769, FBgn0037270). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:4712882..4714182. It has the cytological map location 82D2. Protein features are: Eukaryotic translation initiation factor 3 subunit F; JAB1/MPN/MOV34 metalloenzyme domain; Rpn11/EIF3F, C-terminal. Its molecular function is described by: thiol-dependent ubiquitin-specific protease activity; translation initiation factor activity; translation initiation factor binding. It is involved in the biological process described with: protein deubiquitination; positive regulation of Notch signaling pathway; salivary gland cell autophagic cell death; translational initiation; autophagic cell death. 6 alleles are reported. The phenotypes of these alleles manifest in: wing margin bristle; wing. The phenotypic classes of alleles include: some die during larval stage; some die during pupal stage; lethal - all die before end of pupal stage; lethal - all die before end of larval stage; lethal; visible. Summary of modENCODE Temporal Expression Profile:  Very high expression at all stages of development.  "
FBgn0019830	colt	-0.523341403	0.14029065	0.999936032	SLC25A20	SLC25A20;SLC25A29;SLC25A47;SLC25A45;SLC25A48	high;low;low;low;low	NA	transmembrane protein	NA	"The gene congested-like trachea is referred to in FlyBase by the symbol Dmel\colt (CG3057, FBgn0019830). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:2768590..2770069. It has the cytological map location 23A5. Protein features are: Mitochondrial carrier domain; Mitochondrial substrate/solute carrier. Its molecular function is described by: carnitine:acyl carnitine antiporter activity; carnitine transmembrane transporter activity. It is involved in the biological process described with: epithelial cell morphogenesis; acyl carnitine transport; liquid clearance, open tracheal system; carnitine transport; phagocytosis; mitochondrial transport. 11 alleles are reported. The phenotypes of these alleles manifest in: wing; embryonic/larval tracheal system; wing vein. The phenotypic classes of alleles include: partially lethal - majority die; female sterile; lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0026403	Ndg	-0.523148991	0.212978936	0.999936032	NA	NID1;NID2;LRP5L	high;moderate;moderate	NA	NA	NA	"The gene Nidogen/entactin is referred to in FlyBase by the symbol Dmel\Ndg (CG12908, FBgn0026403). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:10313891..10322104. It has the cytological map location 47A1. Protein features are: EGF domain; EGF-like calcium-binding domain; EGF-like calcium-binding, conserved site; EGF-like domain; EGF-like, conserved site; EGF-type aspartate/asparagine hydroxylation site; G2 nidogen/fibulin G2F; Green fluorescent protein; Growth factor receptor cysteine-rich domain; LDLR class B repeat; NIDO domain; Six-bladed beta-propeller, TolB-like. Its molecular function is described by: calcium ion binding. It is involved in the biological process described with: cell-matrix adhesion. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; flight defective; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages.  "
FBgn0051324	CG31324	-0.522979464	0.196459741	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31324 (FBgn0051324). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:26106868..26130674. It has the cytological map location 96F14-97A1. Its molecular function is unknown. The biological processes in which it is involved are not known. 8 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the pupal period, in adult female stages.  "
FBgn0032154	mtDNA-helicase	-0.522750475	0.193672492	0.999936032	NA	TWNK	high	NA	NA	NA	"The gene mitochondrial DNA helicase is referred to in FlyBase by the symbol Dmel\mtDNA-helicase (CG5924, FBgn0032154). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:9891255..9893446. It has the cytological map location 30E1. Protein features are: DNA helicase, DnaB-like, C-terminal; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: 2 iron, 2 sulfur cluster binding; 5'-3' DNA helicase activity; double-stranded DNA binding; single-stranded DNA binding; ATP binding. It is involved in the biological process described with: protein homooligomerization; mitochondrial genome maintenance; mitochondrial DNA replication. 20 alleles are reported. The phenotypes of these alleles manifest in: wing disc; wing disc posterior compartment. The phenotypic classes of alleles include: increased mortality; increased mortality during development; phenotype; lethal - all die before end of P-stage; lethal - all die before end of pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0000099	ap	-0.52222613	0.201112494	0.999936032	NA	LHX2;LHX9	high;moderate	NA	NA	NA	NA
FBgn0030081	CG7246	-0.522099693	0.192868466	0.999936032	UTP6	UTP6	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7246 (FBgn0030081). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:9078823..9081057. It has the cytological map location 8C4. Protein features are: HAT (Half-A-TPR) repeat; Tetratricopeptide-like helical domain; U3 small nucleolar RNA-associated protein 6. Its molecular function is described by: snoRNA binding. It is involved in the biological process described with: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); positive regulation of multicellular organism growth; cellular response to starvation. 2 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; embryonic/larval neuroblast; mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: increased mortality; increased mortality during development; phenotype; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0027945	ppl	-0.52198202	0.172472335	0.999936032	NA	GCSH	high	DNA-binding with transcription factor activity	NA	NA	"The gene pumpless is referred to in FlyBase by the symbol Dmel\ppl (CG7758, FBgn0027945). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:21280491..21281506. It has the cytological map location 78C4. Protein features are: 2-oxo acid dehydrogenase, lipoyl-binding site; Biotin/lipoyl attachment; Glycine cleavage system H-protein; Glycine cleavage system H-protein, subgroup; Glycine cleavage system H-protein/Simiate; Single hybrid motif. Its molecular function is unknown. It is involved in the biological process described with: wing disc development; glycine catabolic process; glycine decarboxylation via glycine cleavage system. 16 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; embryonic/larval pharynx; embryonic/larval digestive system. The phenotypic classes of alleles include: lethal; increased mortality; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed during early larval stages.  "
FBgn0051301	CG31301	-0.521346484	0.175138388	0.999936032	NA	NKRF;CDKN2AIP;CDKN2AIPNL	high;moderate;moderate	Maybe TF	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31301 (FBgn0051301). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:15346205..15348012. It has the cytological map location 88F1. Protein features are: G-patch domain; NF-kappaB-repression factor, R3H domain; R3H domain; XRN-Two Binding Domain, XTBD. Its molecular function is described by: nucleic acid binding. It is involved in the biological process described with: signal transduction. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0037478	CG2656	-0.520306596	0.171999957	0.999936032	NA	GPN3	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG2656 (FBgn0037478). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:7144724..7151270. It has the cytological map location 84C6. Protein features are: GPN-loop GTPase; GPN-loop GTPase 3; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: GTPase activity. It is involved in the biological process described with: neuron projection morphogenesis; RNA polymerase III complex localization to nucleus; RNA polymerase II complex import to nucleus. 11 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; ganglion mother cell. The phenotypic classes of alleles include: visible; lethal - all die during P-stage; viable; lethal; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, during early pupal stages, in stages of adults of both sexes.  "
FBgn0003517	sta	-0.519851912	0.139781893	0.999936032	NA	RPSA;RPSAP58	high;moderate	NA	NA	NA	"The gene stubarista is referred to in FlyBase by the symbol Dmel\sta (CG14792, FBgn0003517). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is X:1481797..1483413. It has the cytological map location 2B1. Protein features are: 40S ribosomal protein SA, C-terminal domain; Ribosomal protein S2; Ribosomal protein S2, conserved site; Ribosomal protein S2, eukaryotic; Ribosomal protein S2, eukaryotic/archaeal; Ribosomal protein S2, flavodoxin-like domain. Its molecular function is described by: ribosome binding; structural constituent of ribosome. It is involved in the biological process described with: ribosomal small subunit assembly; cytoplasmic translation; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); translation; rRNA export from nucleus; endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA). 32 alleles are reported. The phenotypes of these alleles manifest in: arista; sarcomere; macrochaeta; primary lobe of embryonic/larval lymph gland; Z disc; antenna; embryonic/larval lymph gland; embryonic/larval somatic muscle. The phenotypic classes of alleles include: lethal; increased mortality during development; phenotype; sterile; wild-type. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages.  "
FBgn0035558	CG11357	-0.519562696	0.194434322	0.999936032	NA	B3GNT8;B3GNT6;B3GALT4;B3GNT9;B3GNT7;B3GNT2;B3GNT4;B3GNT3;B3GALT1	high;moderate;high;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11357 (FBgn0035558). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 3L:4542051..4553457. It has the cytological map location 64B9. Protein features are: Glycosyl transferase, family 31. Its molecular function is described by: transferase activity, transferring glycosyl groups; galactosyltransferase activity. It is involved in the biological process described with: protein glycosylation. 14 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: learning defective; viable; fertile; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0004169	up	-0.519504845	0.153298015	0.999936032	NA	TNNT2;TNNT1;TNNT3	high;moderate;moderate	NA	NA	NA	"The gene upheld is referred to in FlyBase by the symbol Dmel\up (CG7107, FBgn0004169). It is a protein_coding_gene from Drosophila melanogaster. It has 18 annotated transcripts and 18 polypeptides (15 unique). Gene sequence location is X:13593474..13602578. It has the cytological map location 12A7. Protein features are: Troponin; Troponin T. Its molecular function is described by: calcium ion binding. It is involved in the biological process described with: regulation of muscle contraction; skeletal muscle thin filament assembly; mitochondrion organization; myofibril assembly; sarcomere organization; mesoderm development; muscle cell cellular homeostasis; muscle organ morphogenesis; cellular calcium ion homeostasis. 18 alleles are reported. The phenotypes of these alleles manifest in: tagmatic subdivision of integument; intracellular membrane-bounded organelle; cuticle; A band; organ system subdivision; depressor muscle; endoplasmic reticulum; endomembrane system; lateral oblique dorsal muscle; M band; dorsal medial muscle; prepupal integumentary system. The phenotypic classes of alleles include: phenotype; viable; increased mortality; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages.  "
FBgn0027657	glob1	-0.519494399	0.151116235	0.999936032	NA	CYGB;HBG2;HBA2;HBE1;HBG1;HBZ;MB;HBQ1;HBB;HBD;HBM;HBA1	high;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"The gene globin 1 is referred to in FlyBase by the symbol Dmel\glob1 (CG9734, FBgn0027657). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (2 unique). Gene sequence location is 3R:15896926..15904521. It has the cytological map location 89A8. Protein features are: Globin; Globin-like. Its molecular function is described by: iron ion binding; heme binding; oxygen binding. It is involved in the biological process described with: oxygen transport; sleep. 12 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval tracheal system. The phenotypic classes of alleles include: phenotype; stress response defective; increased mortality; some die during larval stage; lethal - all die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 06-24 hour embryonic stages, during early larval stages, in adult male stages.  "
FBgn0005278	Sam-S	-0.519412341	0.148268363	0.999936032	NA	MAT2A;MAT1A	high;moderate	NA	NA	NA	"The gene S-adenosylmethionine Synthetase is referred to in FlyBase by the symbol Dmel\Sam-S (CG2674, FBgn0005278). It is a protein_coding_gene from Drosophila melanogaster. It has 12 annotated transcripts and 12 polypeptides (6 unique). Gene sequence location is 2L:106903..114432. It has the cytological map location 21B2. Protein features are: S-adenosylmethionine synthetase; S-adenosylmethionine synthetase superfamily; S-adenosylmethionine synthetase, C-terminal; S-adenosylmethionine synthetase, N-terminal; S-adenosylmethionine synthetase, central domain; S-adenosylmethionine synthetase, conserved site. Its molecular function is described by: ATP binding; methionine adenosyltransferase activity. It is involved in the biological process described with: wing disc development; determination of adult lifespan; S-adenosylmethionine biosynthetic process; chaeta development. 18 alleles are reported. The phenotypes of these alleles manifest in: macrochaeta; scutellar bristle; eye; trichogen cell; mesothoracic tergum; male genitalia; tergite. The phenotypic classes of alleles include: increased mortality during development; phenotype; increased mortality; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0001089	Gal	-0.518583405	0.144364953	0.999936032	NA	GLB1L;GLB1;GLB1L2;GLB1L3;TMPPE	moderate;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene ‘_ galactosidase is referred to in FlyBase by the symbol Dmel\Gal (CG9092, FBgn0001089). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:6003574..6006827. It has the cytological map location 26B2. Protein features are: Beta-galactosidase 1-like; Beta-galactosidase jelly roll domain; Galactose-binding domain-like; Glycoside hydrolase 35, catalytic domain; Glycoside hydrolase superfamily; Glycoside hydrolase, family 35. Its molecular function is described by: beta-galactosidase activity; protein homodimerization activity. It is involved in the biological process described with: galactose metabolic process. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed at stages throughout the pupal period.  "
FBgn0038744	CG4733	-0.518393217	0.213262973	0.999936032	PPP2R3B	PPP2R3B;PPP2R3A;PPP2R3C	high;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4733 (FBgn0038744). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3R:19890689..19898738. It has the cytological map location 92B4-92B6. Protein features are: EF-Hand 1, calcium-binding site; EF-hand domain; EF-hand domain pair. Its molecular function is described by: calcium ion binding. It is involved in the biological process described with: lateral inhibition. 4 alleles are reported. The phenotypes of these alleles manifest in: chaeta; mesothoracic tergum. The phenotypic classes of alleles include: body color defective; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during late pupal stages, in adult male stages.  "
FBgn0032020	strat	-0.518256705	0.185163459	0.999936032	NA	RABIF	high	NA	NA	NA	"The gene stratum is referred to in FlyBase by the symbol Dmel\strat (CG7787, FBgn0032020). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:8320328..8321285. It has the cytological map location 29A4. Protein features are: Mss4; Mss4-like. Its molecular function is described by: guanyl-nucleotide exchange factor activity; zinc ion binding; Rab guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: positive regulation of GTPase activity; small GTPase mediated signal transduction; post-Golgi vesicle-mediated transport; polarized secretion of basement membrane proteins in epithelium. 11 alleles are reported. The phenotypes of these alleles manifest in: follicle cell; ovarian basement membrane. The phenotypic classes of alleles include: some die during pupal stage; partially lethal - majority die; exocytosis defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.  "
FBgn0033471	CG12134	-0.515796407	0.182913952	0.999936032	WDR89	WDR89	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12134 (FBgn0033471). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:9971143..9972780. It has the cytological map location 46C9. Protein features are: WD40 repeat; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0035901	CG6745	-0.514157111	0.216849217	0.999936032	PUS7	PUS7;PUS7L	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6745 (FBgn0035901). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:8510003..8513007. It has the cytological map location 66D5. Protein features are: Pseudouridine synthase, TruD; Pseudouridine synthase, TruD, insertion domain; Pseudouridine synthase, catalytic domain. Its molecular function is described by: pseudouridine synthase activity; RNA binding. It is involved in the biological process described with: pseudouridine synthesis. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during pupal stage; partially lethal - majority die; viable; short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0026755	Ugt37b1	-0.513928371	0.157326738	0.999936032	NA	UGT1A3;UGT2B10;UGT1A1;UGT3A1;UGT8;UGT2B4;UGT2B15;UGT2B28;UGT2A2;UGT3A2;UGT2B17;UGT2B11;UGT2A3;UGT2B7	moderate;low;low;low;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene UDP-glycosyltransferase 37b1 is referred to in FlyBase by the symbol Dmel\Ugt37b1 (CG9481, FBgn0026755). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:6225048..6226842. It has the cytological map location 26B11. Protein features are: UDP-glucuronosyl/UDP-glucosyltransferase. Its molecular function is described by: UDP-glycosyltransferase activity; glucuronosyltransferase activity. It is involved in the biological process described with: UDP-glucose metabolic process. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages.  "
FBgn0038733	CG11407	-0.51333191	0.176122318	0.999936032	NA	ACSF2;ACSF3	low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11407 (FBgn0038733). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:19781246..19783145. It has the cytological map location 92B2. Protein features are: AMP-binding enzyme, C-terminal domain; AMP-binding, conserved site; AMP-dependent synthetase/ligase; Luciferase, N-terminal domain. Its molecular function is described by: catalytic activity. It is involved in the biological process described with: bioluminescence; sleep. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable; lethal - all die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0037433	CG17919	-0.513287596	0.179647446	0.999936032	NA	PEBP1;PEBP4	moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17919 (FBgn0037433). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:6344029..6345087. It has the cytological map location 83E4. Protein features are: Phosphatidylethanolamine-binding protein; Phosphatidylethanolamine-binding, conserved site. Its molecular function is described by: anion binding. It is involved in the biological process described with: response to bacterium; multicellular organism reproduction. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late pupal stages.  "
FBgn0038774	CG5023	-0.513199494	0.175846382	0.999936032	CNN1	TAGLN2;CNN1;TAGLN3;TAGLN;CNN3;CNN2	moderate;high;moderate;moderate;moderate;moderate	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG5023 (FBgn0038774). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:20169435..20174872. It has the cytological map location 92D2-92D3. Protein features are: Calponin homology domain; Calponin repeat; Calponin/LIMCH1; Smooth muscle protein/calponin. Its molecular function is described by: actin binding. It is involved in the biological process described with: actomyosin structure organization. 8 alleles are reported. The phenotypes of these alleles manifest in: sarcomere; myofibril; indirect flight muscle. The phenotypic classes of alleles include: flightless; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages.
FBgn0016123	Alp4	-0.513139567	0.156594853	0.999936032	NA	ALPP;ALPPL2;ALPI;ALPL	moderate;moderate;moderate;moderate	NA	NA	NA	"The gene Alkaline phosphatase 4 is referred to in FlyBase by the symbol Dmel\Alp4 (CG1462, FBgn0016123). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:31048929..31052540. It has the cytological map location 100B1. Protein features are: Alkaline phosphatase; Alkaline phosphatase, active site; Alkaline phosphatase-like, alpha/beta/alpha; Alkaline-phosphatase-like, core domain. Its molecular function is described by: alkaline phosphatase activity. It is involved in the biological process described with: multicellular organism reproduction; epithelial fluid transport; nervous system development; dephosphorylation. 8 alleles are reported. The phenotypes of these alleles manifest in: wing; adult Malpighian tubule. The phenotypic classes of alleles include: visible; viable; lethal; stress response defective; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during early larval stages, in adult male stages.  "
FBgn0039611	CG14528	-0.512744227	0.18595875	0.999936032	NA	ECE2;ECE1;KEL;MME;ECEL1	moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14528 (FBgn0039611). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:28875621..28877805. It has the cytological map location 98F1. Protein features are: Metallopeptidase, catalytic domain; Peptidase M13; Peptidase M13, C-terminal domain; Peptidase M13, N-terminal domain. Its molecular function is described by: metalloendopeptidase activity. It is involved in the biological process described with: proteolysis. 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 06-24 hour embryonic stages, during early larval stages, during late pupal stages.  "
FBgn0038275	CG3817	-0.512295568	0.20458838	0.999936032	NA	RRP15	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3817 (FBgn0038275). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:14898739..14899617. It has the cytological map location 88D6. Protein features are: Ribosomal RNA-processing protein 15. Its molecular function is unknown. It is involved in the biological process described with: maturation of 5.8S rRNA; maturation of LSU-rRNA. 3 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; ganglion mother cell; embryonic/larval neuroblast. The phenotypic classes of alleles include: neuroanatomy defective; lethal; lethal - all die during larval stage; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0038032	CG10096	-0.511929959	0.162634199	0.999936032	NA	FAR1;FAR2	moderate;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10096 (FBgn0038032). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3R:12390166..12395980. It has the cytological map location 87B9. Protein features are: Fatty acyl-CoA reductase; Fatty acyl-CoA reductase, C-terminal; Male sterility, NAD-binding; NAD(P)-binding domain. Its molecular function is described by: fatty-acyl-CoA reductase (alcohol-forming) activity. It is involved in the biological process described with: wax biosynthetic process; long-chain fatty-acyl-CoA metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed in adult male stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0051259	CG31259	-0.511726511	0.154198027	0.999936032	NA	TMEM135	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31259 (FBgn0051259). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:8523944..8526667. It has the cytological map location 85A2. Protein features are: Transmembrane protein 135; Transmembrane protein 135, N-terminal domain. Its molecular function is described by: . It is involved in the biological process described with: peroxisome organization. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages.  "
FBgn0036367	CG10116	-0.511544417	0.1461156	0.999936032	NA	PNLIPRP2;PNLIP;LIPH;PLA1A;PNLIPRP1;LIPI;PNLIPRP3;LIPG;LPL;LIPC	low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10116 (FBgn0036367). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:13456208..13457238. It has the cytological map location 70B1. Protein features are: Alpha/Beta hydrolase fold; Lipase/vitellogenin; Triacylglycerol lipase family. Its molecular function is described by: lipase activity; carboxylic ester hydrolase activity. It is involved in the biological process described with: lipid catabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0024558	Dph5	-0.511272653	0.15645465	0.999936032	NA	DPH5	high	NA	NA	NA	"The gene Diphthamide methyltransferase is referred to in FlyBase by the symbol Dmel\Dph5 (CG31289, FBgn0024558). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:22582028..22583225. It has the cytological map location 94B5. Protein features are: Diphthine synthase; Tetrapyrrole methylase; Tetrapyrrole methylase, subdomain 1; Tetrapyrrole methylase, subdomain 2. Its molecular function is described by: diphthine synthase activity. It is involved in the biological process described with: peptidyl-diphthamide biosynthetic process from peptidyl-histidine. 5 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; lethal; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0033454	CG1671	-0.510814903	0.177236399	0.999936032	TBL3	TBL3	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1671 (FBgn0033454). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:9848061..9850642. It has the cytological map location 46B4. Protein features are: G-protein beta WD-40 repeat; Small-subunit processome, Utp13; WD40 repeat; WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: snoRNA binding. It is involved in the biological process described with: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); cellular response to starvation. 3 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval neuroblast; ganglion mother cell; Z disc; sarcomere. The phenotypic classes of alleles include: neuroanatomy defective; some die during pupal stage; lethal - all die before end of pupal stage; lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0032404	RpL7-like	-0.50926784	0.161649492	0.999936032	NA	RPL7;RPL7L1	moderate;low	Co-factor	NA	NA	"The gene Ribosomal protein L7-like is referred to in FlyBase by the symbol Dmel\RpL7-like (CG5317, FBgn0032404). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:12056326..12058251. It has the cytological map location 33C1. Protein features are: Ribosomal protein L30, ferredoxin-like fold domain; Ribosomal protein L7, eukaryotic. Its molecular function is described by: RNA binding; structural constituent of ribosome. It is involved in the biological process described with: maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); cytoplasmic translation. 7 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval salivary gland; ganglion mother cell; embryonic/larval neuroblast. The phenotypic classes of alleles include: lethal; viable; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0259098	CG42246	-0.509234106	0.225193434	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG42246 (FBgn0259098). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:7411267..7411906. It has the cytological map location 7B2. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0051098	CG31098	-0.509022003	0.159604151	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31098 (FBgn0051098). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:25291370..25292977. It has the cytological map location 96C9-96D1. Protein features are: CHK kinase-like; Protein kinase-like domain; Protein of unknown function DUF227. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0027621	Pfrx	-0.508879118	0.183926055	0.999936032	NA	PFKFB3;PFKFB1;PFKFB4;PFKFB2	high;high;high;moderate	NA	NA	NA	"The gene 6-phosphofructo-2-kinase is referred to in FlyBase by the symbol Dmel\Pfrx (CG3400, FBgn0027621). It is a protein_coding_gene from Drosophila melanogaster. It has 13 annotated transcripts and 13 polypeptides (3 unique). Gene sequence location is X:19495505..19509350. It has the cytological map location 18C8. Protein features are: 6-phosphofructo-2-kinase; Fructose-2,6-bisphosphatase; Histidine phosphatase superfamily; Histidine phosphatase superfamily, clade-1; P-loop containing nucleoside triphosphate hydrolase; Phosphoglycerate/bisphosphoglycerate mutase, active site. Its molecular function is described by: fructose-2,6-bisphosphate 2-phosphatase activity; 6-phosphofructo-2-kinase activity; ATP binding. It is involved in the biological process described with: fructose 2,6-bisphosphate metabolic process; glycolytic process; fructose metabolic process; carbohydrate phosphorylation. 37 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: sleep defective; partially lethal; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 18-24 hour embryonic stages, in stages of adults of both sexes.  "
FBgn0042641	frc	-0.507936558	0.155714013	0.999936032	NA	SLC35D1;SLC35D2;SLC35D3	high;moderate;moderate	NA	transmembrane protein	NA	"The gene fringe connection is referred to in FlyBase by the symbol Dmel\frc (CG3874, FBgn0042641). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:17428936..17433190. It has the cytological map location 74B5-74C1. Protein features are: Sugar phosphate transporter domain. Its molecular function is described by: UDP-glucose transmembrane transporter activity; UDP-xylose transmembrane transporter activity; antiporter activity; UDP-galactose transmembrane transporter activity; UDP-glucuronic acid transmembrane transporter activity; UDP-N-acetylglucosamine transmembrane transporter activity. It is involved in the biological process described with 11 unique terms, many of which group under: single-organism developmental process; sensory organ development; multicellular organism development; pattern specification process; system development; post-embryonic animal morphogenesis; single-multicellular organism process; compound eye development; tube morphogenesis; UDP-glucose transport; developmental process. 22 alleles are reported. The phenotypes of these alleles manifest in: embryonic segment; non-connected developing system; head segment; denticle field; wing margin; embryonic/first instar larval cuticle; denticle belt; presumptive embryonic/larval nervous system; early extended germ band embryo; antennal segment. The phenotypic classes of alleles include: embryonic/larval segmentation phenotype; partially lethal; increased mortality; visible; lethal - all die before end of prepupal stage; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0038256	CG7530	-0.507897515	0.217861808	0.999936032	PAQR3	PAQR3	high	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG7530 (FBgn0038256). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3R:14724760..14731509. It has the cytological map location 88D1-88D2. Protein features are: AdipoR/Haemolysin-III-related. Its molecular function is described by: receptor activity. The biological processes in which it is involved are not known. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: chemical resistant; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0025366	Ip259	-0.507888404	0.15590953	0.999936032	NA	NSA2	high	NA	NA	NA	"The gene Intronic Protein 259 is referred to in FlyBase by the symbol Dmel\Ip259 (CG5277, FBgn0025366). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:10408352..10409610. It has the cytological map location 31E1. Protein features are: Ribosomal protein S8e/ribosomal biogenesis NSA2. Its molecular function is unknown. It is involved in the biological process described with: phagocytosis; maturation of 5.8S rRNA; maturation of LSU-rRNA. 5 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; embryonic/larval neuroblast. The phenotypic classes of alleles include: neuroanatomy defective; partially lethal; lethal - all die during larval stage; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.  "
FBgn0052484	Sk2	-0.507887754	0.203479817	0.999936032	NA	SPHK1;SPHK2	high;moderate	NA	NA	NA	"The gene Sphingosine kinase 2 is referred to in FlyBase by the symbol Dmel\Sk2 (CG32484, FBgn0052484). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:3047087..3050159. It has the cytological map location 63A3-63A4. Protein features are: Diacylglycerol kinase, catalytic domain; Inorganic polyphosphate/ATP-NAD kinase, domain 1; NAD kinase/diacylglycerol kinase-like domain. Its molecular function is described by: D-erythro-sphingosine kinase activity; NAD+ kinase activity; diacylglycerol kinase activity. It is involved in the biological process described with: oviposition; sphingolipid metabolic process; phosphorylation; flight behavior. 10 alleles are reported. The phenotypes of these alleles manifest in: eye; rhabdomere; lipid particle; photoreceptor cell; adult fat body; ommatidium. The phenotypic classes of alleles include: female sterile; fertile; phenotype; increased mortality during development; viable; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0023542	Nmd3	-0.507242717	0.159319014	0.999936032	NA	NMD3	high	NA	NA	NA	"The gene Nonsense-mediated mRNA 3 is referred to in FlyBase by the symbol Dmel\Nmd3 (CG3460, FBgn0023542). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:2182818..2184668. It has the cytological map location 2E1. Protein features are: NMD3. Its molecular function is described by: ribosomal large subunit binding. It is involved in the biological process described with: ribosomal large subunit export from nucleus; cellular response to starvation. 6 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval neuroblast; ganglion mother cell; mesothoracic tergum. The phenotypic classes of alleles include: visible; increased mortality during development; phenotype; increased mortality; lethal - all die during larval stage; partially lethal; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 06-12 and 18-24 hour embryonic stages, during early larval stages.  "
FBgn0266581	pit	-0.507035351	0.181305923	0.999936032	NA	DDX18	high	NA	NA	NA	"The gene pitchoune is referred to in FlyBase by the symbol Dmel\pit (CG6375, FBgn0266581). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:22034298..22038925. It has the cytological map location 94A1. Protein features are: DEAD/DEAH box helicase domain; Domain of unknown function DUF4217; Helicase superfamily 1/2, ATP-binding domain; Helicase, C-terminal; P-loop containing nucleoside triphosphate hydrolase; RNA helicase, DEAD-box type, Q motif. Its molecular function is described by: ATP binding; ATP-dependent RNA helicase activity; nucleic acid binding; RNA helicase activity. It is involved in the biological process described with: RNA secondary structure unwinding; cell proliferation; cell growth. 13 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval salivary gland; embryonic precursor cell of adult midgut; wing disc; imaginal precursor; embryonic/larval midgut; wing disc posterior compartment. The phenotypic classes of alleles include: phenotype; increased mortality during development; lethal; lethal - all die during larval stage; increased mortality."
FBgn0030484	GstT4	-0.50694386	0.149036446	0.999936032	NA	GSTT2;GSTT2B;GSTT1	moderate;moderate;low	NA	NA	NA	"The gene Glutathione S transferase T4 is referred to in FlyBase by the symbol Dmel\GstT4 (CG1681, FBgn0030484). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:13404749..13409323. It has the cytological map location 11F4. Protein features are: Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Thioredoxin-like fold. Its molecular function is unknown. It is involved in the biological process described with: . 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; flightless; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages.  "
FBgn0029798	CG4078	-0.506562805	0.228088934	0.999936032	RTEL1	RTEL1;BRIP1	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4078 (FBgn0029798). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:5747747..5752077. It has the cytological map location 5B6. Protein features are: ATP-dependent helicase, C-terminal; DEAD2; DNA helicase (DNA repair), Rad3 type; Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type; Helicase-like, DEXD box c2 type; P-loop containing nucleoside triphosphate hydrolase; Regulator of telomere elongation helicase 1. Its molecular function is described by: ATP binding; ATP-dependent DNA helicase activity; DNA binding. It is involved in the biological process described with: regulation of double-strand break repair via homologous recombination; DNA replication; telomere maintenance. 4 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; flight defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0032321	YL-1	-0.506514792	0.22555249	0.999936032	VPS72	VPS72	high	DNA-binding with transcription factor activity(YL1|YL1_C)	NA	NA	"The gene YL-1 is referred to in FlyBase by the symbol Dmel\YL-1 (CG4621, FBgn0032321). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:10970443..10972093. It has the cytological map location 32C1. Protein features are: Vps72/YL1 family; Vps72/YL1, C-terminal. Its molecular function is described by: histone acetyltransferase activity. It is involved in the biological process described with: regulation of transcription, DNA-templated; negative regulation of gene expression; histone exchange; histone acetylation. 7 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: viable; female semi-sterile; visible; partially lethal; female fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early pupal stages, in adult female stages.  "
FBgn0039789	CG9717	-0.506140533	0.225048963	0.999936032	NA	SLC26A11;SLC26A3;SLC26A6;SLC26A5;SLC26A9;SLC26A1;SLC26A2;SLC26A8;SLC26A4	moderate;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9717 (FBgn0039789). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:30584020..30587302. It has the cytological map location 99F10. Protein features are: SLC26A/SulP transporter; SLC26A/SulP transporter domain; STAS domain. Its molecular function is described by: secondary active sulfate transmembrane transporter activity; bicarbonate transmembrane transporter activity; anion:anion antiporter activity; sulfate transmembrane transporter activity; chloride channel activity; oxalate transmembrane transporter activity. It is involved in the biological process described with: bicarbonate transport; regulation of intracellular pH; sulfate transport; chloride transmembrane transport; regulation of membrane potential. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during early pupal stages.  "
FBgn0031815	frj	-0.506005034	0.158909605	0.999936032	MBOAT7	MBOAT7	high	NA	transmembrane protein	NA	"The gene farjavit is referred to in FlyBase by the symbol Dmel\frj (CG9526, FBgn0031815). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:6456052..6459008. It has the cytological map location 26D5. Protein features are: Membrane bound O-acyl transferase, MBOAT. Its molecular function is described by: lysophospholipid acyltransferase activity. It is involved in the biological process described with: lipid modification. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0033971	CG10209	-0.505879619	0.211828888	0.999936032	NA	NAIF1	low	DNA-binding with transcription factor activity(BESS)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10209 (FBgn0033971). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:14846064..14848366. It has the cytological map location 51C5. Protein features are: BESS motif; Myb/SANT-like DNA-binding domain; Nuclear apoptosis-inducing factor 1. Its molecular function is described by: DNA binding. It is involved in the biological process described with: apoptotic process. 7 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: lethal; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0038088	CG10126	-0.505663159	0.206731693	0.999936032	CAPSL	CAPSL;CAPS;CAPS2	moderate;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10126 (FBgn0038088). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:12855544..12859246. It has the cytological map location 87D2. Protein features are: EF-Hand 1, calcium-binding site; EF-hand domain; EF-hand domain pair. Its molecular function is described by: calcium ion binding. The biological processes in which it is involved are not known. 4 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval neuroblast; ganglion mother cell. The phenotypic classes of alleles include: partially lethal; phenotype; increased mortality during development; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0010223	Galphaf	-0.504861999	0.161036099	0.999936032	NA	GNAL;GNAS	moderate;moderate	NA	NA	NA	"The gene G protein ‘± f subunit is referred to in FlyBase by the symbol Dmel\G‘±f (CG12232, FBgn0010223). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:16662557..16667934. It has the cytological map location 73B5. Protein features are: G protein alpha subunit, helical insertion; Guanine nucleotide binding protein (G-protein), alpha subunit; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: G-protein beta/gamma-subunit complex binding; guanyl nucleotide binding; G-protein coupled receptor binding; signal transducer activity; GTPase activity. It is involved in the biological process described with: mesoderm development; positive regulation of hemocyte proliferation; regulation of filopodium assembly; adenylate cyclase-activating dopamine receptor signaling pathway; sensory perception of chemical stimulus. 11 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval hemocyte; filopodium. The phenotypic classes of alleles include: partially lethal; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0259979	CG17337	-0.504731946	0.152553595	0.999936032	NA	CNDP2;CNDP1	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17337 (FBgn0259979). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:5697872..5700212. It has the cytological map location 41F9-41F11. Protein features are: ArgE/DapE/ACY1/CPG2/YscS, conserved site; Cytosolic nonspecific dipeptidase/DUG1; Peptidase M20; Peptidase M20, dimerisation domain. Its molecular function is described by: dipeptidase activity; metallopeptidase activity. It is involved in the biological process described with: proteolysis. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages.  "
FBgn0265180	CG44245	-0.504523263	0.214780793	0.999936032	NA	GYG1;GYG2	high;moderate	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG44245 (FBgn0265180). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:21200483..21212969. It has the cytological map location 57D1. Its molecular function is described by: . It is involved in the biological process described with: mesoderm development. 7 alleles are reported. No phenotypic data is available. No phenotypic class data is available.
FBgn0031589	CG3714	-0.504247045	0.189410074	0.999936032	NAPRT1	NAPRT	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3714 (FBgn0031589). It is a protein_coding_gene from Drosophila melanogaster. It has 8 annotated transcripts and 8 polypeptides (4 unique). Gene sequence location is 2L:4189340..4198071. It has the cytological map location 24D8. Protein features are: Nicotinate phosphoribosyltransferase family; Nicotinate phosphoribosyltransferase pncB-type; Quinolinate phosphoribosyl transferase, C-terminal. Its molecular function is described by: nicotinate phosphoribosyltransferase activity; nicotinate-nucleotide diphosphorylase (carboxylating) activity. It is involved in the biological process described with: response to oxidative stress; nicotinate nucleotide salvage; NAD biosynthetic process. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed during late larval stages.  "
FBgn0002780	mod	-0.502843976	0.171983281	0.999936032	NA	NCL	high	DNA-binding with transcription factor activity	NA	NA	"The gene modulo is referred to in FlyBase by the symbol Dmel\mod (CG2050, FBgn0002780). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:32052060..32054974. It has the cytological map location 100E3. Protein features are: RNA recognition motif domain. Its molecular function is described by: DNA binding; sequence-specific DNA binding; protein binding; mRNA binding. It is involved in the biological process described with: spermatid development; cell proliferation. 28 alleles are reported. The phenotypes of these alleles manifest in: larva; abdomen; eo-type sensillum; muscle cell; gnathal segment; chaeta; adult thoracic segment; mechanosensory chaeta; embryonic/larval posterior spiracle; embryonic/larval digestive system; adult head. The phenotypic classes of alleles include: cell size defective; increased mortality during development; phenotype; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0039274	CG11920	-0.502307976	0.204650326	0.999936032	IMP4	IMP4	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG11920 (FBgn0039274). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:25074877..25076382. It has the cytological map location 96B20. Protein features are: Anticodon-binding; Brix domain. Its molecular function is described by: snoRNA binding; rRNA primary transcript binding. It is involved in the biological process described with: rRNA processing; cellular response to starvation. 5 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0026261	bonsai	-0.502000217	0.181540611	0.999936032	NA	MRPS15	high	NA	NA	NA	"The gene bonsai is referred to in FlyBase by the symbol Dmel\bonsai (CG4207, FBgn0026261). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:22637770..22638868. It has the cytological map location 58F3. Protein features are: Ribosomal protein S15; Ribosomal protein S15, bacterial-type; S15/NS1, RNA-binding. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: regulation of growth; translation; mitochondrial translation. 10 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; adult; mesothoracic tergum. The phenotypic classes of alleles include: increased mortality during development; phenotype; lethal - all die before end of larval stage; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in adult female stages.  "
FBgn0015766	Msr-110	-0.501684906	0.158463457	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene Msr-110 is referred to in FlyBase by the symbol Dmel\Msr-110 (CG10596, FBgn0015766). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 3L:5566919..5577348. It has the cytological map location 64D3. Protein features are: Genetic suppressor element-like. Its molecular function is described by: . It is involved in the biological process described with: . 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal; flight defective; viable; short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0038662	Mpc1	-0.501271469	0.163303414	0.999936032	MPC1	MPC1;MPC1L	high;moderate	NA	NA	NA	"The gene Mitochondrial pyruvate carrier is referred to in FlyBase by the symbol Dmel\Mpc1 (CG14290, FBgn0038662). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:18926996..18928659. It has the cytological map location 91D5. Protein features are: Mitochondrial pyruvate carrier. Its molecular function is described by: pyruvate transmembrane transporter activity. It is involved in the biological process described with: mitochondrial pyruvate transport; pyruvate metabolic process; mitochondrial pyruvate transmembrane transport. 8 alleles are reported. The phenotype of these alleles manifest in: neurite. The phenotypic classes of alleles include: neuroanatomy defective; viable; fertile; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0032699	CG10383	-0.501193148	0.179966278	0.999936032	SERAC1	SERAC1	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10383 (FBgn0032699). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:18690904..18695602. It has the cytological map location 37A1. Protein features are: Alpha/Beta hydrolase fold; Armadillo-like helical; Armadillo-type fold; GPI inositol-deacylase PGAP1-like. Its molecular function is described by: hydrolase activity, acting on ester bonds. It is involved in the biological process described with: determination of adult lifespan; sleep. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; long lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, during late pupal stages, in adult male stages.  "
FBgn0030518	CG11134	-0.500770142	0.162911142	0.999936032	APIP	APIP	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11134 (FBgn0030518). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:13737942..13739177. It has the cytological map location 12B4. Protein features are: Class II aldolase/adducin N-terminal; Methylthioribulose-1-phosphate dehydratase; Methylthioribulose-1-phosphate dehydratase, eukaryotes. Its molecular function is described by: methylthioribulose 1-phosphate dehydratase activity; zinc ion binding. It is involved in the biological process described with: L-methionine salvage from methylthioadenosine. 6 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval hemocyte. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed during early larval stages.  "
FBgn0033769	CG8768	-0.500397402	0.188391365	0.999936032	SDR39U1	SDR39U1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8768 (FBgn0033769). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:12691308..12692690. It has the cytological map location 49C1. Protein features are: Domain of unknown function DUF1731; Epimerase family protein SDR39U1; NAD(P)-binding domain; NAD-dependent epimerase/dehydratase. Its molecular function is described by: coenzyme binding; catalytic activity. The biological processes in which it is involved are not known. 4 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: visible; viable; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed during late pupal stages, in stages of adults of both sexes.  "
FBgn0033744	Dh44-R2	-0.500014625	0.182657095	0.999936032	NA	CRHR2;CRHR1;CRHR1-IT1-CRHR1;CALCRL;CALCR	high;moderate;moderate;low;low	DNA-binding with transcription factor activity	transmembrane protein	GPCR	"The gene Diuretic hormone 44 receptor 2 is referred to in FlyBase by the symbol Dmel\Dh44-R2 (CG12370, FBgn0033744). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:12474424..12487986. It has the cytological map location 49A7-49A9. Protein features are: GPCR, family 2, diuretic hormone receptor; GPCR, family 2, extracellular hormone receptor domain; GPCR, family 2, secretin-like; GPCR, family 2, secretin-like, conserved site; GPCR, family 2-like. Its molecular function is described by: diuretic hormone receptor activity; calcitonin receptor activity; G-protein coupled receptor activity; neuropeptide receptor activity. It is involved in the biological process described with: G-protein coupled receptor signaling pathway; response to salt stress; hormone-mediated signaling pathway; cell surface receptor signaling pathway. 13 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; osmotic stress response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 06-12 and 18-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages.  "
FBgn0039844	CG1607	-0.49999461	0.208875808	0.999936032	SLC7A6	SLC7A8;SLC7A5;SLC7A6;SLC7A10;SLC7A7;SLC7A9;SLC7A11	moderate;moderate;moderate;moderate;moderate;moderate;low	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG1607 (FBgn0039844). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3R:31382109..31391893. It has the cytological map location 100C2-100C3. Protein features are: Amino acid/polyamine transporter I. Its molecular function is described by: L-amino acid transmembrane transporter activity; antiporter activity; amino acid transmembrane transporter activity. It is involved in the biological process described with: amino acid transmembrane transport. 10 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum. The phenotypic classes of alleles include: viable; visible; body color defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during early pupal stages.
FBgn0038307	mRpS10	-0.499860595	0.180518497	0.999936032	NA	MRPS10	high	NA	NA	NA	"The gene mitochondrial ribosomal protein S10 is referred to in FlyBase by the symbol Dmel\mRpS10 (CG4247, FBgn0038307). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:15229665..15230516. It has the cytological map location 88E3. Protein features are: Ribosomal protein S10 domain. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation; translation. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal - all die during P-stage; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during late pupal stages, in adult female stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0050489	Cyp12d1-p	-0.499831375	0.166826061	0.999936032	NA	CYP27A1;CYP24A1;CYP27C1;CYP27B1	moderate;low;low;low	NA	NA	NA	"The gene Cyp12d1-p is referred to in FlyBase by the symbol Dmel\Cyp12d1-p (CG30489, FBgn0050489). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:11117225..11121884. It has the cytological map location 47D4. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Its molecular function is described by: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; iron ion binding; heme binding. It is involved in the biological process described with: oxidation-reduction process; response to insecticide; response to DDT. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: chemical resistant. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed at stages throughout the larval period, during early pupal stages, in adult male stages.  "
FBgn0053969	CG33969	-0.498780584	0.182202727	0.999936032	NA	FBXW4	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG33969 (FBgn0053969). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:20391685..20393553. It has the cytological map location 77C1. Protein features are: Leucine-rich repeat domain, L domain-like; Six-bladed beta-propeller, TolB-like; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0026189	prominin-like	-0.498721247	0.220304462	0.999936032	NA	PROM1;PROM2	high;moderate	NA	transmembrane protein	NA	"The gene prominin-like is referred to in FlyBase by the symbol Dmel\prominin-like (CG7740, FBgn0026189). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (3 unique). Gene sequence location is 3L:3114450..3127724. It has the cytological map location 63B1-63B3. Protein features are: Prominin. Its molecular function is unknown. It is involved in the biological process described with: neuron projection morphogenesis. 13 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 06-18 hour embryonic stages, at stages throughout the pupal period.  "
FBgn0263748	CG43673	-0.498218429	0.155902345	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG43673 (FBgn0263748). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:15779146..15780214. It has the cytological map location 13E17. Protein features are: Chitin binding domain. Its molecular function is described by: chitin binding. It is involved in the biological process described with: chitin metabolic process. 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available.
FBgn0038126	CG8483	-0.49798759	0.233711424	0.999936032	NA	PI15;CLEC18C;CRISPLD1;CLEC18B;CRISPLD2;CLEC18A;R3HDML;PI16;CRISP2;CRISP1	high;moderate;moderate;moderate;moderate;moderate;low;moderate;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8483 (FBgn0038126). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:13208754..13214465. It has the cytological map location 87E2. Protein features are: Allergen V5/Tpx-1-related, conserved site; CAP domain; Cysteine-rich  secretory protein, allergen V5/Tpx-1-related; Myc-type, basic helix-loop-helix (bHLH) domain; Ves allergen. Its molecular function is described by: protein dimerization activity. It is involved in the biological process described with: . 9 alleles are reported. The phenotypes of these alleles manifest in: chaeta; mesothoracic tergum. The phenotypic classes of alleles include: some die during pupal stage; partially lethal - majority die; visible; lethal; body color defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the pupal period.  "
FBgn0037848	Tsp86D	-0.497820602	0.185225372	0.999936032	TSPAN33	TSPAN33;TSPAN14;TSPAN10;ROM1;TSPAN17;TSPAN5	high;low;moderate;moderate;low;low	NA	transmembrane protein	NA	"The gene Tetraspanin 86D is referred to in FlyBase by the symbol Dmel\Tsp86D (CG4591, FBgn0037848). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:10868708..10870555. It has the cytological map location 86C7. Protein features are: Tetraspanin; Tetraspanin, EC2 domain; Tetraspanin, conserved site; Tetraspanin/Peripherin. Its molecular function is described by: . It is involved in the biological process described with: positive regulation of Notch signaling pathway; cell surface receptor signaling pathway; border follicle cell migration; nervous system development. 6 alleles are reported. The phenotype of these alleles manifest in: sensory mother cell. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0038183	CG9286	-0.497466759	0.189955085	0.999936032	BCCIP	BCCIP	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG9286 (FBgn0038183). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:13780964..13782082. It has the cytological map location 87F13. Protein features are: BCP1 family. Its molecular function is described by: protein kinase regulator activity. It is involved in the biological process described with: regulation of protein kinase activity. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed during early larval stages.
FBgn0029723	Proc-R	-0.497211683	0.234336481	0.999936032	NA	GPR18;CCR1;GPR139	low;low;low	NA	transmembrane protein	GPCR	"The gene Proctolin receptor is referred to in FlyBase by the symbol Dmel\Proc-R (CG6986, FBgn0029723). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is X:4707916..4729487. It has the cytological map location 4C14-4C15. Protein features are: 7TM GPCR, serpentine receptor class w (Srw); G protein-coupled receptor, rhodopsin-like; GPCR, rhodopsin-like, 7TM. Its molecular function is described by: G-protein coupled receptor activity; neuropeptide receptor activity; proctolin receptor activity. It is involved in the biological process described with: G-protein coupled receptor signaling pathway; neuropeptide signaling pathway. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0027571	FASN1	-0.497205701	0.188505579	0.999936032	NA	FASN	moderate	NA	NA	NA	NA
FBgn0053970	CG33970	-0.496712829	0.211373248	0.999936032	NA	ABCG2;ABCA3;ABCA12;ABCA5;ABCA10;ABCA2;ABCA4;ABCA13;ABCA1;ABCA6;ABCA8;ABCA7;ABCA9	low;low;low;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG33970 (FBgn0053970). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:26318355..26362588. It has the cytological map location 97A8-97A10. Protein features are: AAA+ ATPase domain; ABC transporter, conserved site; ABC transporter-like; ABC-2 transporter; ABC-2 type transporter; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: ATPase activity; ATP binding. It is involved in the biological process described with: transport. 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: flightless; lethal; viable; sleep defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early pupal stages.  "
FBgn0014026	RpL7A	-0.495507515	0.157191193	0.999936032	NA	RPL7A	high	NA	NA	NA	"The gene Ribosomal protein L7A is referred to in FlyBase by the symbol Dmel\RpL7A (CG3314, FBgn0014026). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is X:6530897..6533348. It has the cytological map location 6B1. Protein features are: 50S ribosomal protein L30e-like; Ribosomal protein L7A/L8; Ribosomal protein L7Ae conserved site; Ribosomal protein L7Ae/L30e/S12e/Gadd45; Ribosomal protein L7Ae/L8/Nhp2 family. Its molecular function is described by: RNA binding; structural constituent of ribosome. It is involved in the biological process described with: maturation of LSU-rRNA; cytoplasmic translation. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during larval stage; increased mortality; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages.  "
FBgn0037749	CG9471	-0.494712858	0.168372943	0.999936032	BLVRB	BLVRB	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9471 (FBgn0037749). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:9770532..9771542. It has the cytological map location 85E8. Protein features are: NAD(P)-binding domain. Its molecular function is unknown. It is involved in the biological process described with: multicellular organism reproduction. 2 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die during P-stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, in adult male stages.  "
FBgn0033184	mEFTu2	-0.494547998	0.170595381	0.999936032	NA	TUFM	moderate	NA	NA	NA	"The gene mitochondrial translation elongation factor Tu 2 is referred to in FlyBase by the symbol Dmel\mEFTu2 (CG12736, FBgn0033184). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:7508527..7510357. It has the cytological map location 43D1. Protein features are: Elongation factor Tu, domain 2; P-loop containing nucleoside triphosphate hydrolase; Small GTP-binding protein domain; Tr-type G domain, conserved site; Transcription factor, GTP-binding domain; Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal; Translation elongation factor EFTu-like, domain 2; Translation elongation factor EFTu/EF1A, C-terminal; Translation protein, beta-barrel domain. Its molecular function is described by: GTP binding; GTPase activity; translation elongation factor activity. It is involved in the biological process described with: translational elongation. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed in adult male stages.  "
FBgn0014028	SdhB	-0.494100312	0.161441946	0.999936032	SDHB	SDHB	high	NA	NA	NA	"The gene Succinate dehydrogenase, subunit B (iron-sulfur) is referred to in FlyBase by the symbol Dmel\SdhB (CG3283, FBgn0014028). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:6807626..6809172. It has the cytological map location 42D3-42D4. Protein features are: 2Fe-2S ferredoxin, iron-sulphur binding site; 2Fe-2S ferredoxin-type iron-sulfur binding domain; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; 4Fe-4S ferredoxin-type, iron-sulphur binding domain; Alpha-helical ferredoxin; Beta-grasp domain; Succinate dehydogenase/fumarate reductase N-terminal; Succinate dehydrogenase/fumarate reductase iron-sulphur protein. Its molecular function is described by: 2 iron, 2 sulfur cluster binding; succinate dehydrogenase (ubiquinone) activity; ubiquinone binding; 4 iron, 4 sulfur cluster binding; 3 iron, 4 sulfur cluster binding; electron carrier activity. It is involved in the biological process described with: tricarboxylic acid cycle; mitochondrial electron transport, succinate to ubiquinone; aerobic respiration. 7 alleles are reported. The phenotypes of these alleles manifest in: flight muscle; mitochondrial crista; wing; mitochondrion. The phenotypic classes of alleles include: gravitaxis defective; oxidative stress response defective; viable; stress response defective; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0023197	Jon74E	-0.492320149	0.158645308	0.999936032	NA	C1S;F9;PROC	low;low;low	NA	NA	NA	"The gene Jonah 74E is referred to in FlyBase by the symbol Dmel\Jon74E (CG6298, FBgn0023197). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:17546739..17549127. It has the cytological map location 74D3-74D4. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed during late larval stages.  "
FBgn0031736	CG11030	-0.492229216	0.192068771	0.999936032	NGDN	NGDN	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11030 (FBgn0031736). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:5724656..5762420. It has the cytological map location 25F3-25F4. Protein features are: Sas10/Utp3/C1D. Its molecular function is unknown. It is involved in the biological process described with: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). 23 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; lethal; fertile; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0037290	CG1124	-0.492082302	0.161708856	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG1124 (FBgn0037290). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:4965445..4968485. It has the cytological map location 82E4. Protein features are: Haemolymph juvenile hormone binding. Its molecular function is unknown. It is involved in the biological process described with: multicellular organism reproduction; circadian rhythm. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during early pupal stages.
FBgn0038366	CG4576	-0.491410628	0.231483856	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4576 (FBgn0038366). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:15825747..15830321. It has the cytological map location 89A5. Protein features are: Acyltransferase 3. Its molecular function is described by: transferase activity, transferring acyl groups other than amino-acyl groups. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, during early pupal stages.  "
FBgn0031824	CG9547	-0.491076821	0.182293915	0.999936032	GCDH	GCDH	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9547 (FBgn0031824). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:6492974..6494532. It has the cytological map location 26D9. Protein features are: Acyl-CoA dehydrogenase/oxidase C-terminal; Acyl-CoA dehydrogenase/oxidase, N-terminal; Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain; Acyl-CoA oxidase/dehydrogenase, central domain. Its molecular function is described by: glutaryl-CoA dehydrogenase activity; flavin adenine dinucleotide binding. It is involved in the biological process described with: tryptophan metabolic process; hydroxylysine catabolic process; oxidation-reduction process; lysine catabolic process. 7 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0266492	SclB	-0.490994865	0.228559621	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Sarcolamban B is referred to in FlyBase by the symbol Dmel\SclB (CG45091, FBgn0266492). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2L:16837972..16841884. It has the cytological map location 36B2. Its molecular function is unknown. It is involved in the biological process described with: regulation of cardiac muscle contraction. 14 alleles are reported. The phenotype of these alleles manifest in: adult heart. No phenotypic class data is available."
FBgn0001099	gdl	-0.490955233	0.242771424	0.999936032	NA	DGCR6L;DGCR6;LOC102724770	high;moderate;moderate	NA	NA	NA	"The gene gonadal is referred to in FlyBase by the symbol Dmel\gdl (CG33756, FBgn0001099). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3L:15509445..15511047. It has the cytological map location 71D3. Protein features are: Gonadal family. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during late pupal stages, in adult male stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0032029	CG17292	-0.49093178	0.184665258	0.999936032	NA	PNLIPRP2;PNLIP;LIPH;PLA1A;PNLIPRP1;LIPI;PNLIPRP3;LIPG;LPL;LIPC	low;low;low;low;low;low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17292 (FBgn0032029). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2L:8370454..8374250. It has the cytological map location 29B2. Protein features are: Alpha/Beta hydrolase fold; Lipase, N-terminal; Lipase/vitellogenin; Triacylglycerol lipase family. Its molecular function is described by: carboxylic ester hydrolase activity. It is involved in the biological process described with: lipid metabolic process. 12 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0022023	eIF3h	-0.49075526	0.164008138	0.999936032	NA	EIF3H	high	NA	NA	NA	"The gene eukaryotic translation initiation factor 3 subunit h is referred to in FlyBase by the symbol Dmel\eIF3h (CG9124, FBgn0022023). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:5051193..5053094. It has the cytological map location 25C3. Protein features are: Eukaryotic translation initiation factor 3 subunit H; JAB1/MPN/MOV34 metalloenzyme domain. Its molecular function is described by: translation initiation factor activity. It is involved in the biological process described with: translational initiation; positive regulation of Notch signaling pathway. 9 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; embryonic/larval neuroblast; wing; embryonic/larval somatic muscle; Z disc; wing margin bristle; sarcomere. The phenotypic classes of alleles include: increased mortality during development; phenotype; increased mortality; lethal. Summary of modENCODE Temporal Expression Profile:  Very high expression at all stages of development.  "
FBgn0033226	CG1882	-0.490593205	0.165028416	0.999936032	ABHD4	ABHD4;ABHD5	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1882 (FBgn0033226). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (2 unique). Gene sequence location is 2R:7812504..7815486. It has the cytological map location 43E18. Protein features are: Alpha/Beta hydrolase fold; Alpha/beta hydrolase fold-1; Epoxide hydrolase-like. Its molecular function is described by: carboxylic ester hydrolase activity; epoxide hydrolase activity. The biological processes in which it is involved are not known. 4 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum. The phenotypic classes of alleles include: fertile; lethal - all die during P-stage; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 18-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0020545	kraken	-0.489848839	0.163925916	0.999936032	SERHL2	SERHL2;SERHL	high;moderate	NA	NA	NA	"The gene kraken is referred to in FlyBase by the symbol Dmel\kraken (CG3943, FBgn0020545). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:852768..854539. It has the cytological map location 21E2. Protein features are: Alpha/Beta hydrolase fold; Alpha/beta hydrolase fold-1. Its molecular function is described by: serine hydrolase activity. It is involved in the biological process described with: response to toxic substance; digestion. 11 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, during early larval stages, in stages of adults of both sexes.  "
FBgn0028336	l(1)G0255	-0.489781407	0.165026772	0.999936032	NA	FH	high	NA	NA	NA	"The gene lethal (1) G0255 is referred to in FlyBase by the symbol Dmel\l(1)G0255 (CG4094, FBgn0028336). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:6678424..6681845. It has the cytological map location 6C5. Protein features are: Fumarase C, C-terminal; Fumarase/histidase, N-terminal; Fumarate hydratase, class II; Fumarate lyase family; Fumarate lyase, N-terminal; Fumarate lyase, conserved site; L-Aspartase-like. Its molecular function is described by: fumarate hydratase activity. It is involved in the biological process described with: malate metabolic process; tricarboxylic acid cycle; fumarate metabolic process. 10 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: viable; visible; lethal - all die before end of larval stage; lethal; some die during larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0003279	RpL4	-0.489689143	0.161465626	0.999936032	NA	RPL4	high	NA	NA	NA	"The gene Ribosomal protein L4 is referred to in FlyBase by the symbol Dmel\RpL4 (CG5502, FBgn0003279). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:27922821..27924888. It has the cytological map location 98B6. Protein features are: 60S ribosomal protein L4, C-terminal domain; Ribosomal protein L4 domain; Ribosomal protein L4/L1e; Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site. Its molecular function is described by: structural constituent of ribosome; RNA binding. It is involved in the biological process described with: cytoplasmic translation; translation. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die during larval stage; lethal; some die during larval stage; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, in adult female stages.  "
FBgn0030309	CG1572	-0.489681763	0.180000362	0.999936032	NA	CKLF;CMTM2;PLP2;CMTM1;CMTM6;CMTM3;CMTM4;CMTM5;CMTM7	low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1572 (FBgn0030309). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is X:11555050..11558654. It has the cytological map location 10C5. Protein features are: Marvel domain. Its molecular function is unknown. It is involved in the biological process described with: positive regulation of hemocyte proliferation. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period.  "
FBgn0036323	CG14118	-0.489587381	0.238182312	0.999936032	NA	ENDOG	moderate	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG14118 (FBgn0036323). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:12892658..12894758. It has the cytological map location 69E8-69F1. Protein features are: DNA/RNA non-specific endonuclease. Its molecular function is described by: metal ion binding; nucleic acid binding; hydrolase activity. It is involved in the biological process described with: apoptotic DNA fragmentation. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during early pupal stages.
FBgn0036877	CG9452	-0.489064182	0.176888813	0.999936032	NA	ACP2;ACPT;ACPP;ACP6	moderate;moderate;moderate;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9452 (FBgn0036877). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:19501010..19503870. It has the cytological map location 76B5. Protein features are: Histidine acid phosphatase active site; Histidine phosphatase superfamily; Histidine phosphatase superfamily, clade-2; Venom acid phosphatase Acph-1. Its molecular function is described by: acid phosphatase activity. It is involved in the biological process described with: dephosphorylation. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during early pupal stages.  "
FBgn0037822	CG14683	-0.488594667	0.184145703	0.999936032	METTL15	METTL15;METTL15P1	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14683 (FBgn0037822). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:10696647..10698976. It has the cytological map location 86C4. Protein features are: Ribosomal RNA small subunit methyltransferase H; S-adenosyl-L-methionine-dependent methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain. Its molecular function is described by: rRNA (cytosine-N4-)-methyltransferase activity. It is involved in the biological process described with: rRNA base methylation. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0015040	Cyp9c1	-0.488441212	0.175386026	0.999936032	CYP3A5	TBXAS1;CYP3A4;CYP3A5;CYP3A43;CYP3A7-CYP3A51P;CYP3A7	high;moderate;moderate;moderate;moderate;low	NA	transmembrane protein	NA	"The gene Cytochrome P450-9c1 is referred to in FlyBase by the symbol Dmel\Cyp9c1 (CG3616, FBgn0015040). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:24631063..24632923. It has the cytological map location 60D10. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Its molecular function is described by: heme binding; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed at stages throughout the larval period, at stages throughout the pupal period.  "
FBgn0041630	Hexo1	-0.487850602	0.164842752	0.999936032	NA	HEXB;HEXA	high;moderate	NA	NA	NA	"The gene Hexosaminidase 1 is referred to in FlyBase by the symbol Dmel\Hexo1 (CG1318, FBgn0041630). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3L:4288641..4291211. It has the cytological map location 64A12. Protein features are: Beta-hexosaminidase; Beta-hexosaminidase, eukaryotic type, N-terminal; Chitobiase/beta-hexosaminidase domain 2-like; Glycoside hydrolase family 20, catalytic domain; Glycoside hydrolase superfamily. Its molecular function is described by: beta-N-acetylglucosaminidase activity. It is involved in the biological process described with: protein deglycosylation; carbohydrate metabolic process; N-glycan processing; rhodopsin biosynthetic process. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed at stages throughout the larval period, at stages throughout the pupal period.  "
FBgn0033574	Spn47C	-0.487194059	0.201827055	0.999936032	NA	SERPINI2;SERPINI1;SERPINE2;SERPINE1;SERPIND1;SERPINB7;SERPINA5;SERPINE3;SERPINB9	moderate;moderate;low;low;low;low;moderate;low;low	NA	NA	NA	"The gene Serpin 47C is referred to in FlyBase by the symbol Dmel\Spn47C (CG7722, FBgn0033574). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:10938425..10941738. It has the cytological map location 47C7. Protein features are: Serpin domain; Serpin family; Serpin, conserved site. Its molecular function is unknown. It is involved in the biological process described with: multicellular organism reproduction. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during early pupal stages, in adult male stages.  "
FBgn0041588	eIF2D	-0.486622431	0.187898892	0.999936032	NA	EIF2D	high	NA	NA	NA	"The gene eukaryotic translation initiation factor 2D is referred to in FlyBase by the symbol Dmel\eIF2D (CG31426, FBgn0041588). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:29149896..29151794. It has the cytological map location 98F13. Protein features are: PUA domain; PUA-like domain; SUI1 domain; SWIB/MDM2 domain; Uncharacterised domain CHP00451. Its molecular function is described by: translation initiation factor activity. It is involved in the biological process described with: IRES-dependent translational initiation; formation of translation preinitiation complex; translational initiation; ribosome disassembly. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages, during early pupal stages, in stages of adults of both sexes.  "
FBgn0037144	CG7458	-0.485766203	0.189733049	0.999936032	NA	SLC22A4;SLC22A5	moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7458 (FBgn0037144). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:21955110..21958041. It has the cytological map location 79A4. Protein features are: Major facilitator superfamily domain; Major facilitator,  sugar transporter-like; Sugar transporter, conserved site. Its molecular function is described by: organic anion transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0001296	kar	-0.484862407	0.214798231	0.999936032	NA	SLC16A10;SLC16A2	high;moderate	NA	transmembrane protein	NA	"The gene karmoisin is referred to in FlyBase by the symbol Dmel\kar (CG12286, FBgn0001296). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:12682186..12689367. It has the cytological map location 87C5. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain; Monocarboxylate transporter 8. Its molecular function is described by: thyroid hormone transmembrane transporter activity; monocarboxylic acid transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; ommochrome biosynthetic process; thyroid hormone transport. 34 alleles are reported. The phenotypes of these alleles manifest in: pigment cell; wing; ocellus; ocellus pigment granule; Malpighian tubule. The phenotypic classes of alleles include: fertile; eye color defective; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 06-24 hour embryonic stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0033426	CG1814	-0.484538818	0.202821635	0.999936032	NT5DC3	NT5DC3;NT5DC2	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1814 (FBgn0033426). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 2R:9577427..9581847. It has the cytological map location 45F4. Protein features are: HAD-like domain; HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase; Purine 5'-nucleotidase. Its molecular function is described by: 5'-nucleotidase activity; single-stranded DNA binding. It is involved in the biological process described with: cellular response to DNA damage stimulus. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0022343	CG3760	-0.484197624	0.177060945	0.999936032	NA	CDV3	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG3760 (FBgn0022343). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 2R:24938181..24939769. It has the cytological map location 60E5. Protein features are: Protein CDV3. Its molecular function is described by: . It is involved in the biological process described with: . 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed during early larval stages.
FBgn0034142	CG8306	-0.483940677	0.178319247	0.999936032	NA	FAR2;FAR1	moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8306 (FBgn0034142). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:16589518..16594646. It has the cytological map location 53C9. Protein features are: Fatty acyl-CoA reductase; Fatty acyl-CoA reductase, C-terminal; Male sterility, NAD-binding; NAD(P)-binding domain. Its molecular function is described by: fatty-acyl-CoA reductase (alcohol-forming) activity; long-chain-fatty-acyl-CoA reductase activity. It is involved in the biological process described with: wax biosynthetic process; long-chain fatty-acyl-CoA metabolic process. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 06-18 hour embryonic stages, during early larval stages.  "
FBgn0000100	RpLP0	-0.48382553	0.165410608	0.999936032	NA	RPLP0;RPLP0P6	high;moderate	NA	NA	NA	"The gene Ribosomal protein LP0 is referred to in FlyBase by the symbol Dmel\RpLP0 (CG7490, FBgn0000100). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:22075867..22077487. It has the cytological map location 79B2. Protein features are: 60S acidic ribosomal protein P0; Ribosomal protein L10P. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: ribosome biogenesis; cytoplasmic translation. 15 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: phenotype; increased mortality during development; lethal - all die before end of prepupal stage; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0040780	Atg10	-0.483157676	0.247424604	0.999936032	NA	ATG10	high	NA	NA	NA	"The gene Autophagy-related 10 is referred to in FlyBase by the symbol Dmel\Atg10 (CG12821, FBgn0040780). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:7832171..7835518. It has the cytological map location 43E18. Protein features are: Autophagy-related protein 3. Its molecular function is described by: Atg12 transferase activity. It is involved in the biological process described with: cellular protein modification process; macroautophagy. 5 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages.  "
FBgn0038053	CG18549	-0.482683	0.219047694	0.999936032	MFSD11	MFSD11	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG18549 (FBgn0038053). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:12449296..12456355. It has the cytological map location 87B11. Protein features are: Ion channel regulatory protein, UNC-93; Major facilitator superfamily domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 10 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed during late larval stages, at stages throughout the pupal period.  "
FBgn0263593	Lpin	-0.482679022	0.174259103	0.999936032	NA	LPIN3;LPIN1;LPIN2	high;moderate;moderate	NA	NA	NA	"The gene Lipin is referred to in FlyBase by the symbol Dmel\Lpin (CG8709, FBgn0263593). It is a protein_coding_gene from Drosophila melanogaster. It has 11 annotated transcripts and 11 polypeptides (9 unique). Gene sequence location is 2R:8136986..8156654. It has the cytological map location 44B4-44B5. Protein features are: HAD-like domain; LNS2/PITP; Lipin, N-terminal; Lipin, middle domain; Lipin/Ned1/Smp2 (LNS2). Its molecular function is described by: transcription coactivator activity; phosphatidate phosphatase activity. It is involved in the biological process described with: lipid homeostasis; imaginal disc-derived wing vein specification; regulation of transcription from RNA polymerase II promoter; regulation of cellular ketone metabolic process; response to starvation; triglyceride biosynthetic process; regulation of fatty acid metabolic process; positive regulation of transcription from RNA polymerase II promoter; fatty acid catabolic process; negative regulation of BMP signaling pathway. 15 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval fat body; germline cell; embryonic/larval brain; intersegmental nerve; wing vein; nucleus; anterior crossvein; lipid particle. The phenotypic classes of alleles include: cell size defective; increased mortality during development; phenotype; increased mortality."
FBgn0035815	Snmp2	-0.482276812	0.249164511	0.999936032	NA	CD36;SCARB1;SCARB2	high;moderate;low	NA	transmembrane protein	NA	"The gene Sensory neuron membrane protein 2 is referred to in FlyBase by the symbol Dmel\Snmp2 (CG7422, FBgn0035815). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:7733250..7743041. It has the cytological map location 66A11. Protein features are: CD36 family. Its molecular function is unknown. It is involved in the biological process described with: sensory perception of pain. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, in adult male stages.  "
FBgn0025620	CG13360	-0.482069363	0.185993478	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG13360 (FBgn0025620). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:787855..790089. It has the cytological map location 1C4. Protein features are: CHK kinase-like; Protein kinase-like domain; Protein of unknown function DUF227. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the larval period.
FBgn0036789	AstC-R2	-0.481671603	0.250285868	0.999936032	NA	SSTR4;SSTR2;SSTR3;SSTR5;SSTR1;OPRD1;OPRK1;NPBWR2;OPRM1;NPBWR1;OPRL1;PTGDR2;GPR1;MCHR2;MCHR1	high;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;low;moderate;moderate;moderate;moderate;moderate	NA	transmembrane protein	GPCR	"The gene Allatostatin C receptor 2 is referred to in FlyBase by the symbol Dmel\AstC-R2 (CG13702, FBgn0036789). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 3L:18485137..18502557. It has the cytological map location 75D1. Protein features are: G protein-coupled receptor, rhodopsin-like; GPCR, rhodopsin-like, 7TM; Somatostatin receptor family. Its molecular function is described by: somatostatin receptor activity; neuropeptide receptor activity; allatostatin receptor activity; neuropeptide binding. It is involved in the biological process described with: neuropeptide signaling pathway; G-protein coupled receptor signaling pathway; G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0038262	CG14857	-0.480712399	0.240034689	0.999936032	NA	SLC22A4;SLC22A5;SLC22A2;SV2C;SV2B;SLC22A24;SLC22A7;SLC22A10;SLC22A12;SLC22A25;SLC22A11;SLC22A9;SLC22A23;SVOP;SLC22A8;SLC22A6;SLC22A1	low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14857 (FBgn0038262). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:14801773..14804342. It has the cytological map location 88D4. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain. Its molecular function is described by: organic anion transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 06-12 and 18-24 hour embryonic stages, during early larval stages.  "
FBgn0011272	RpL13	-0.480688246	0.168609951	0.999936032	NA	RPL13	high	NA	NA	NA	"The gene Ribosomal protein L13 is referred to in FlyBase by the symbol Dmel\RpL13 (CG4651, FBgn0011272). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:9967313..9968645. It has the cytological map location 30F3. Protein features are: Ribosomal protein L13, eukaryotic; Ribosomal protein L13e; Ribosomal protein L13e, conserved site. Its molecular function is described by: RNA binding; structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; translation. 7 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0028662	VhaPPA1-1	-0.480256096	0.168327258	0.999936032	NA	ATP6V0B	high	NA	transmembrane protein	NA	"The gene Vacuolar H<sup>+</sup> ATPase PPA1 subunit 1 is referred to in FlyBase by the symbol Dmel\VhaPPA1-1 (CG7007, FBgn0028662). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:14902330..14904061. It has the cytological map location 88D6. Protein features are: V-ATPase proteolipid subunit; V-ATPase proteolipid subunit C-like domain. Its molecular function is described by: proton-transporting ATPase activity, rotational mechanism; hydrogen ion transmembrane transporter activity. It is involved in the biological process described with: ATP hydrolysis coupled proton transport; vacuolar acidification; terminal branching, open tracheal system. 7 alleles are reported. The phenotypes of these alleles manifest in: terminal tracheal cell; sarcomere; Z disc; tracheal stalk cell; mesothoracic tergum; chaeta. The phenotypic classes of alleles include: visible; increased mortality during development; phenotype; lethal; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0045852	ham	-0.480006051	0.246926736	0.999936032	NA	MECOM;PRDM16	high;moderate	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene hamlet is referred to in FlyBase by the symbol Dmel\ham (CG31753, FBgn0045852). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is 2L:18762874..18792906. It has the cytological map location 37A2-37A4. Protein features are: Evi1/Prdm16; Zinc finger C2H2-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: nucleic acid binding; transcription factor activity, sequence-specific DNA binding. It is involved in the biological process described with: dendrite morphogenesis; regulation of transcription, DNA-templated; negative regulation of cell proliferation; neuron development; regulation of dendrite development; neuroblast fate commitment. 12 alleles are reported. The phenotypes of these alleles manifest in: stem cell; embryo; sensory cluster; presumptive embryonic/larval system; tormogen cell; neuroblast; embryonic abdomen; embryonic/larval sense organ; developing embryonic structure; type II neuroblast; embryonic/larval nervous system; chaeta; ganglion mother cell; type I neuroblast; larval abdomen. The phenotypic classes of alleles include: phenotype; visible; stress response defective; sensory perception defective; cell size defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages.  "
FBgn0023527	CG3071	-0.479664243	0.189999613	0.999936032	UTP15	UTP15	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3071 (FBgn0023527). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:2262837..2264825. It has the cytological map location 2F2. Protein features are: U3 small nucleolar RNA-associated protein 15, C-terminal; WD40 repeat; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: snoRNA binding. It is involved in the biological process described with: positive regulation of transcription from RNA polymerase I promoter; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); cellular response to starvation. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during pupal stage; lethal - all die before end of pupal stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, during early larval stages.  "
FBgn0038964	Nop56	-0.479480121	0.173522121	0.999936032	NOP56	NOP56	high	NA	NA	NA	"The gene Nop56 is referred to in FlyBase by the symbol Dmel\Nop56 (CG13849, FBgn0038964). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:22419095..22421068. It has the cytological map location 94A12. Protein features are: NOP5, N-terminal; NOSIC; Nop domain; Winged helix-turn-helix DNA-binding domain. Its molecular function is described by: snoRNA binding. It is involved in the biological process described with: cellular response to starvation; rRNA modification. 5 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval neuroblast; ganglion mother cell. The phenotypic classes of alleles include: neuroanatomy defective; lethal - all die during embryonic stage; lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0052302	CG32302	-0.47928467	0.247554959	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32302 (FBgn0052302). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:2268825..2269903. It has the cytological map location 62D4-62D5. Protein features are: Chitin binding domain. Its molecular function is described by: chitin binding. It is involved in the biological process described with: chitin metabolic process. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages.  "
FBgn0035917	Zasp66	-0.47925079	0.176637966	0.999936032	NA	LDB3;PDLIM7;PDLIM3;PDLIM1	moderate;low;moderate;moderate	NA	NA	NA	"The gene Z band alternatively spliced PDZ-motif protein 66 is referred to in FlyBase by the symbol Dmel\Zasp66 (CG6416, FBgn0035917). It is a protein_coding_gene from Drosophila melanogaster. It has 12 annotated transcripts and 12 polypeptides (11 unique). Gene sequence location is 3L:8624371..8638813. It has the cytological map location 66D9. Protein features are: Domain of unknown function DUF4749; LIM and senescent cell antigen-like-containing domain protein 1; PDZ domain; Zasp-like motif. Its molecular function is described by: protein phosphatase 1 binding; muscle alpha-actinin binding. It is involved in the biological process described with: mesoderm development; myofibril assembly. 10 alleles are reported. The phenotypes of these alleles manifest in: M band; indirect flight muscle; myofibril; Z disc. The phenotypic classes of alleles include: viable; majority die during pupal stage; fertile; flightless; lethal; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0034602	Lapsyn	-0.478963049	0.191167648	0.999936032	NA	TLR3	low	NA	transmembrane protein	NA	"The gene Leucine-rich repeat activity-regulated protein at synapses is referred to in FlyBase by the symbol Dmel\Lapsyn (CG15658, FBgn0034602). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:21193571..21199431. It has the cytological map location 57C9-57D1. Protein features are: Leucine-rich repeat; Leucine-rich repeat domain, L domain-like; Leucine-rich repeat, typical subtype. Its molecular function is unknown. It is involved in the biological process described with: nervous system development. 14 alleles are reported. The phenotypes of these alleles manifest in: neuromuscular junction; varicosity; synapse; NMJ bouton. The phenotypic classes of alleles include: wild-type; lethal; increased mortality; lethal - all die before end of first instar larval stage; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0039628	CG11841	-0.478830603	0.238123654	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11841 (FBgn0039628). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:29051056..29052267. It has the cytological map location 98F6. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during pupal stage; partially lethal - majority die; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed in adult male stages.  "
FBgn0039115	CG10214	-0.478765734	0.193784437	0.999936032	REXO2	REXO2	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10214 (FBgn0039115). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:23766519..23767488. It has the cytological map location 95B1. Protein features are: Exonuclease, RNase T/DNA polymerase III; Oligoribonuclease; Ribonuclease H-like domain. Its molecular function is described by: 3'-5'-exoribonuclease activity; oligonucleotidase activity; nucleic acid binding. It is involved in the biological process described with: nucleic acid phosphodiester bond hydrolysis; cellular response to starvation. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0032394	CG6746	-0.478689909	0.174889558	0.999936032	PTPLB	HACD2;HACD1;HACD3;HACD4	high;moderate;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6746 (FBgn0032394). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:12001234..12002266. It has the cytological map location 33B5-33B6. Protein features are: Protein-tyrosine phosphatase-like, PTPLA. Its molecular function is described by: 3-hydroxyacyl-CoA dehydratase activity; enzyme binding. It is involved in the biological process described with: very long-chain fatty acid biosynthetic process; sphingolipid biosynthetic process; fatty acid elongation. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; song defective; lethal; locomotor behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 12-18 embryonic stages, during early larval stages, in adult male stages.  "
FBgn0036191	Sugb	-0.478666297	0.184177577	0.999936032	NA	MFSD6L	high	NA	transmembrane protein	NA	"The gene Sugar baby is referred to in FlyBase by the symbol Dmel\Sugb (CG7334, FBgn0036191). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3L:11683980..11690155. It has the cytological map location 68D2. Protein features are: Major facilitator superfamily associated domain; Major facilitator superfamily domain. Its molecular function is unknown. It is involved in the biological process described with: determination of adult lifespan. 14 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: long lived; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed in adult female stages.  "
FBgn0033382	Hydr1	-0.478601782	0.18173783	0.999936032	ABHD3	ABHD3;ABHD1	high;moderate	NA	transmembrane protein	NA	"The gene ‘±/‘_ hydrolase 1 is referred to in FlyBase by the symbol Dmel\Hydr1 (CG8058, FBgn0033382). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (2 unique). Gene sequence location is 2R:9132480..9135453. It has the cytological map location 45A11. Protein features are: AB hydrolase 4 family; AB hydrolase 4, conserved site; Alpha/Beta hydrolase fold; Alpha/beta hydrolase fold-1. Its molecular function is described by: lipase activity. It is involved in the biological process described with: lipid metabolic process; cellular lipid metabolic process. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed in adult male stages.  "
FBgn0037723	SpdS	-0.478499565	0.20362835	0.999936032	SRM	SRM	high	NA	NA	NA	"The gene Spermidine Synthase is referred to in FlyBase by the symbol Dmel\SpdS (CG8327, FBgn0037723). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:9631641..9633673. It has the cytological map location 85E1-85E2. Protein features are: Polyamine biosynthesis  domain; Polyamine biosynthesis domain, conserved site; S-adenosyl-L-methionine-dependent methyltransferase; Spermidine synthase, tetramerisation domain; Spermidine/spermine synthase, eukaryotes; Spermidine/spermine synthases. Its molecular function is described by: spermidine synthase activity. It is involved in the biological process described with: spermidine biosynthetic process. 13 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: long lived; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0032482	Pect	-0.477566695	0.192884128	0.999936032	PCYT2	PCYT2	high	NA	NA	NA	"The gene Phosphoethanolamine cytidylyltransferase is referred to in FlyBase by the symbol Dmel\Pect (CG5547, FBgn0032482). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 2L:13203762..13210828. It has the cytological map location 34A9. Protein features are: Cytidyltransferase-like domain; Rossmann-like alpha/beta/alpha sandwich fold. Its molecular function is described by: catalytic activity. It is involved in the biological process described with: ethanolamine-containing compound metabolic process; biosynthetic process. 10 alleles are reported. The phenotype of these alleles manifest in: adult heart. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed in adult male stages.  "
FBgn0014342	mia	-0.477560904	0.227012746	0.999936032	NA	TAF6;TAF6L	moderate;high	DNA-binding with transcription factor activity	NA	NA	"The gene meiosis I arrest is referred to in FlyBase by the symbol Dmel\mia (CG10390, FBgn0014342). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:5548115..5551168. It has the cytological map location 83B1. Protein features are: Armadillo-like helical; Histone-fold; TAF6, C-terminal HEAT repeat domain. Its molecular function is described by: transcription factor activity, sequence-specific DNA binding; protein heterodimerization activity. It is involved in the biological process described with: spermatogenesis; spermatid development; regulation of gene expression; regulation of sequence-specific DNA binding transcription factor activity; meiotic cell cycle; spermatid differentiation; male meiosis I; transcription initiation from RNA polymerase II promoter. 11 alleles are reported. The phenotypes of these alleles manifest in: testis; spermatocyte. The phenotypic classes of alleles include: viable; male sterile; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0031453	Bacc	-0.477550577	0.173400561	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Bacchus is referred to in FlyBase by the symbol Dmel\Bacc (CG9894, FBgn0031453). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2L:2752445..2757975. It has the cytological map location 23A3. Its molecular function is unknown. It is involved in the biological process described with: behavioral response to ethanol; inter-male aggressive behavior. 66 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; flight defective; fertile; behavior defective; chemical resistant; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period.  "
FBgn0036369	CG10089	-0.477150717	0.245129846	0.999936032	DUSP22	DUSP22;DUSP15;STYX;DUSP12;DUSP19	high;moderate;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10089 (FBgn0036369). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (4 unique). Gene sequence location is 3L:13465552..13474787. It has the cytological map location 70B1-70B2. Protein features are: Atypical dual specificity phosphatase; Dual specificity phosphatase; Dual specificity phosphatase, catalytic domain; Dual specificity protein phosphatase domain; Protein-tyrosine phosphatase-like; Tyrosine specific protein phosphatases domain. Its molecular function is described by: protein tyrosine/serine/threonine phosphatase activity. It is involved in the biological process described with: protein dephosphorylation. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: female semi-sterile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed in adult male stages.  "
FBgn0029885	CG3224	-0.476997158	0.191157612	0.999936032	ZNF593	ZNF593	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3224 (FBgn0029885). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:6660552..6661462. It has the cytological map location 6C3-6C4. Protein features are: Matrin/U1-C-like, C2H2-type zinc finger; Zinc finger C2H2-type; Zinc finger, double-stranded RNA binding. Its molecular function is described by: nucleic acid binding; zinc ion binding; ribosomal large subunit binding. It is involved in the biological process described with: ribosomal large subunit export from nucleus. 4 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval neuroblast; ganglion mother cell; trichogen cell. The phenotypic classes of alleles include: lethal; lethal - all die during larval stage; visible; viable; neuroanatomy defective; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0039883	RhoGAP100F	-0.476877515	0.251575476	0.999936032	NA	SYDE1;SYDE2	high;moderate	NA	NA	NA	"The gene Rho GTPase activating protein at 100F is referred to in FlyBase by the symbol Dmel\RhoGAP100F (CG1976, FBgn0039883). It is a protein_coding_gene from Drosophila melanogaster. It has 8 annotated transcripts and 8 polypeptides (all unique). Gene sequence location is 3R:31812609..31846570. It has the cytological map location 100D2-100D3. Protein features are: C2 domain; PDZ domain; Rho GTPase activation protein; Rho GTPase-activating protein domain. Its molecular function is described by: GTPase activator activity. It is involved in the biological process described with: signal transduction; maintenance of presynaptic active zone structure; axon extension involved in axon guidance; Rho protein signal transduction; cytoskeletal matrix organization at active zone; synaptic vesicle localization; activation of GTPase activity; regulation of GTPase activity; R7 cell development. 26 alleles are reported. The phenotype of these alleles manifest in: photoreceptor cell R7. The phenotypic class of alleles includes: neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period.  "
FBgn0262022	CG42833	-0.476352162	0.243959127	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG42833 (FBgn0262022). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:20200093..20200487. It has the cytological map location 77A2. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported.
FBgn0030658	CG7872	-0.475649654	0.186504678	0.999936032	DNAJC25	DNAJC25;DNAJC25-GNG10	high;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7872 (FBgn0030658). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:15578205..15579857. It has the cytological map location 13D4. Protein features are: DnaJ domain; DnaJ domain, conserved site. Its molecular function is described by: . It is involved in the biological process described with: . 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0010770	ppan	-0.475414756	0.209847383	0.999936032	NA	PPAN;PPAN-P2RY11;P2RY11	high;moderate;moderate	NA	NA	NA	"The gene peter pan is referred to in FlyBase by the symbol Dmel\ppan (CG5786, FBgn0010770). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:21116254..21117899. It has the cytological map location 93B13. Protein features are: Brix domain. Its molecular function is described by: rRNA binding. It is involved in the biological process described with: female gamete generation; ribosomal large subunit assembly; larval development; imaginal disc development. 12 alleles are reported. The phenotypes of these alleles manifest in: somatic precursor cell; chaeta; adult cuticle; egg; embryonic/larval neuroblast; eye; cuticular specialization; cuticle; mesothoracic bristle; somatic stem cell; gamete. The phenotypic classes of alleles include: wild-type; partially lethal - majority die; phenotype; increased mortality during development; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0034988	cN-IIIB	-0.475135466	0.178017074	0.999936032	NA	NT5C3B;NT5C3A	high;moderate	NA	NA	NA	"The gene cytosolic 5'-nucleotidase IIIB is referred to in FlyBase by the symbol Dmel\cN-IIIB (CG3362, FBgn0034988). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:24195498..24197027. It has the cytological map location 60C2. Protein features are: HAD-like domain; Pyrimidine 5'-nucleotidase, eukaryotic. Its molecular function is described by: 5'-nucleotidase activity; magnesium ion binding; nucleotidase activity. It is involved in the biological process described with: ribonucleoside monophosphate catabolic process; dephosphorylation; guanosine-containing compound catabolic process. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0016041	Tom40	-0.473879321	0.183172532	0.999936032	NA	TOMM40;TOMM40L	high;moderate	NA	NA	NA	"The gene Translocase of outer membrane 40 is referred to in FlyBase by the symbol Dmel\Tom40 (CG12157, FBgn0016041). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is X:7736893..7739978. It has the cytological map location 7B7. Protein features are: Eukaryotic porin/Tom40. Its molecular function is described by: P-P-bond-hydrolysis-driven protein transmembrane transporter activity; protein channel activity. It is involved in the biological process described with: protein targeting to mitochondrion; protein import into mitochondrial matrix; cellular response to hypoxia. 4 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: phenotype; increased mortality during development; lethal; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in adult female stages.  "
FBgn0003261	Rm62	-0.473567344	0.177321643	0.999936032	NA	DDX17;DDX5	moderate;moderate	NA	NA	NA	"The gene Rm62 is referred to in FlyBase by the symbol Dmel\Rm62 (CG10279, FBgn0003261). It is a protein_coding_gene from Drosophila melanogaster. It has 12 annotated transcripts and 12 polypeptides (8 unique). Gene sequence location is 3R:6000426..6008579. It has the cytological map location 83D1-83D2. Protein features are: ATP-dependent RNA helicase DEAD-box, conserved site; DEAD/DEAH box helicase domain; Helicase superfamily 1/2, ATP-binding domain; Helicase, C-terminal; P-loop containing nucleoside triphosphate hydrolase; RNA helicase, DEAD-box type, Q motif. Its molecular function is described by: ATP-dependent RNA helicase activity; ATP binding; protein binding; nucleic acid binding; mRNA binding. It is involved in the biological process described with: RNA interference; mRNA splicing, via spliceosome; antimicrobial humoral response; regulation of defense response to virus; RNA secondary structure unwinding; regulation of alternative mRNA splicing, via spliceosome. 45 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; class IV dendritic arborizing neuron; pigment cell; wing; trichogen cell; ganglion mother cell. The phenotypic classes of alleles include: neuroanatomy defective; sterile; flightless; developmental rate defective; visible; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.  "
FBgn0260390	CG42516	-0.473512314	0.210638414	0.999936032	NA	GTF3C6	low	DNA-binding with transcription factor activity	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG42516 (FBgn0260390). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:8129354..8131323. It has the cytological map location 44B3. Protein features are: Transcription factor TFIIIC, tau55-related. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0051793	CG31793	-0.473424314	0.209102838	0.999936032	NA	ABCC4;ABCC3;ABCC1;ABCC8;ABCC9;ABCC6;ABCC10;ABCC2;ABCC5;CFTR;ABCC12;ABCC11	moderate;moderate;moderate;low;low;low;low;low;low;moderate;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31793 (FBgn0051793). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:19003367..19008234. It has the cytological map location 37B9. Protein features are: AAA+ ATPase domain; ABC transporter type 1, transmembrane domain; ABC transporter, conserved site; ABC transporter-like; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: ATPase activity, coupled to transmembrane movement of substances; ATP binding. It is involved in the biological process described with: transmembrane transport. 8 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0030406	CG1463	-0.471554722	0.210829775	0.999936032	ZNHIT6	ZNHIT6	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1463 (FBgn0030406). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is X:12609977..12611667. It has the cytological map location 11B3. Protein features are: Zinc finger, HIT-type. Its molecular function is unknown. It is involved in the biological process described with: neuron projection morphogenesis. 5 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0029898	CG14439	-0.470579211	0.262820467	0.999936032	NA	SPNS1;SPNS2;SPNS3	low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14439 (FBgn0029898). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is X:6747544..6755752. It has the cytological map location 6C11-6C12. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain. Its molecular function is unknown. It is involved in the biological process described with: transmembrane transport. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during early pupal stages.  "
FBgn0050043	CG30043	-0.470387902	0.191361249	0.999936032	NA	ERMP1	moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG30043 (FBgn0050043). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:12359436..12363165. It has the cytological map location 49A1. Protein features are: Peptidase M28. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal; lethal - all die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during late larval stages.  "
FBgn0267758	CR46089	-0.470075393	0.223893267	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR46089 (FBgn0267758). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3R:23052916..23057984. It has the cytological map location 94D10. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0030870	CG6398	-0.470018837	0.263437599	0.999936032	NA	CLDND1;CACNG5;CACNG7	low;low;low	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG6398 (FBgn0030870). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:17830828..17841705. It has the cytological map location 16D5-16D7. Protein features are: PMP-22/EMP/MP20/Claudin superfamily. Its molecular function is unknown. The biological processes in which it is involved are not known. 12 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages.
FBgn0037770	Art4	-0.469612939	0.233515914	0.999936032	CARM1	CARM1	high	NA	NA	NA	"The gene Arginine methyltransferase 4 is referred to in FlyBase by the symbol Dmel\Art4 (CG5358, FBgn0037770). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:9982816..9986060. It has the cytological map location 85F4. Protein features are: PH domain-like; Protein arginine N-methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase. Its molecular function is described by: protein-arginine omega-N asymmetric methyltransferase activity; protein-arginine omega-N monomethyltransferase activity; histone-arginine N-methyltransferase activity; histone methyltransferase activity. It is involved in the biological process described with: histone methylation; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine; regulation of transcription, DNA-templated; histone arginine methylation. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0034829	CG9899	-0.469355492	0.175834987	0.999936032	NA	CTR9	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9899 (FBgn0034829). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:23153854..23162077. It has the cytological map location 59D1. Protein features are: RNA polymerase-associated protein Ctr9; Tetratricopeptide repeat; Tetratricopeptide repeat-containing domain; Tetratricopeptide-like helical domain. Its molecular function is described by: SH2 domain binding; RNA polymerase II core binding. It is involved in the biological process described with: positive regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-templated; regulation of histone H3-K4 methylation. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed in adult male stages.  "
FBgn0003068	per	-0.469199929	0.244457206	0.999936032	NA	PER3;PER2;PER1	high;high;moderate	Co-factor	NA	NA	"The gene period is referred to in FlyBase by the symbol Dmel\per (CG2647, FBgn0003068). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:2685580..2692780. It has the cytological map location 3B1-3B2. Protein features are: PAS domain; PAS fold. Its molecular function is described by: protein homodimerization activity; transcription factor binding; protein binding; protein heterodimerization activity; transcription corepressor activity; transcription cofactor activity. It is involved in the biological process described with 27 unique terms, many of which group under: response to abiotic stimulus; rhythmic behavior; locomotor rhythm; response to stress; response to oxidative stress; circadian rhythm; memory; regulation of transcription regulatory region DNA binding; temperature homeostasis; male courtship behavior, veined wing vibration. 242 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; pericardial cell; trichogen cell; Malpighian tubule; posterior adult hindgut; adult heart; indirect flight muscle motor neuron MN5. The phenotypic classes of alleles include: phenotype; mating defective; visible; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed during late pupal stages, in stages of adults of both sexes.  "
FBgn0086856	CG11555	-0.469116049	0.228808306	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11555 (FBgn0086856). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:273836..274766. It has the cytological map location 21B7-21B8. Its molecular function is unknown. The biological processes in which it is involved are not known. 10 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; embryonic/larval neuroblast; ganglion mother cell; mesothoracic tergum. The phenotypic classes of alleles include: increased mortality; increased mortality during development; viable; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0015568	alpha-Est1	-0.469109108	0.186550053	0.999936032	NA	ACHE;CES4A;CES2;NLGN2;CES5A;CES1;CEL;NLGN4X;NLGN1;NLGN3;NLGN4Y;CES3	low;low;low;low;low;low;low;low;low;low;low;low	NA	NA	NA	"The gene ‘±-Esterase-1 is referred to in FlyBase by the symbol Dmel\‘±-Est1 (CG1031, FBgn0015568). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:7545733..7549124. It has the cytological map location 84D9. Protein features are: Alpha/Beta hydrolase fold; Carboxylesterase, type B. Its molecular function is unknown. It is involved in the biological process described with: sensory perception of pain. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0002306	sas	-0.469035238	0.241806342	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene stranded at second is referred to in FlyBase by the symbol Dmel\sas (CG2507, FBgn0002306). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3R:7162808..7183702. It has the cytological map location 84C8-84D1. Protein features are: Fibronectin type III; Immunoglobulin-like fold; VWFC domain. Its molecular function is described by: receptor activity. It is involved in the biological process described with: axon guidance; instar larval development. 34 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval cuticle; embryonic/larval salivary gland; anterior commissure; embryonic/larval tracheal system; embryonic/larval trachea; longitudinal connective. The phenotypic classes of alleles include: cell adhesion defective; increased mortality; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages, at stages throughout the pupal period.  "
FBgn0036020	CG8336	-0.468628696	0.216799605	0.999936032	PPID	PPID;PPIL6;PPIG;NKTR;PPIH	high;moderate;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8336 (FBgn0036020). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 3L:9628676..9631795. It has the cytological map location 67C2-67C3. Protein features are: Cyclophilin-like domain; Cyclophilin-type peptidyl-prolyl cis-trans isomerase; Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain; Tetratricopeptide repeat; Tetratricopeptide repeat-containing domain; Tetratricopeptide-like helical domain. Its molecular function is described by: peptidyl-prolyl cis-trans isomerase activity. It is involved in the biological process described with: protein peptidyl-prolyl isomerization. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0035103	Vdup1	-0.468167974	0.264589477	0.999936032	NA	ARRDC1;TXNIP;ARRDC4;ARRDC2;ARRDC3;ARRDC5	high;moderate;low;low;low;moderate	NA	NA	NA	"The gene Vitamin D<down>3</down> up-regulated protein 1 is referred to in FlyBase by the symbol Dmel\Vdup1 (CG7047, FBgn0035103). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is 3L:176306..178963. It has the cytological map location 61B2. Protein features are: Arrestin C-terminal-like domain; Arrestin-like, N-terminal; Immunoglobulin E-set. Its molecular function is unknown. It is involved in the biological process described with: negative regulation of gene expression. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 06-24 hour embryonic stages, at stages throughout the pupal period.  "
FBgn0039868	CG11563	-0.468118048	0.220406643	0.999936032	NA	NOP16	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG11563 (FBgn0039868). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:31737035..31737999. It has the cytological map location 100D1-100D2. Protein features are: Ribosome biogenesis protein Nop16. Its molecular function is described by: RNA binding. It is involved in the biological process described with: ribosomal large subunit biogenesis. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.
FBgn0262476	CG43066	-0.467886628	0.250582302	0.999936032	NA	SLC6A18;SLC6A19;SLC6A20;SLC6A15;SLC6A17;SLC6A16;SLC6A9;SLC6A5;SLC6A3;SLC6A11;SLC6A8;SLC6A13;SLC6A12;SLC6A6;SLC6A4;SLC6A14;SLC6A1;SLC6A2	high;high;high;high;high;moderate;low;low;low;low;moderate;low;low;low;low;low;low;low	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG43066 (FBgn0262476). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:18514574..18526439. It has the cytological map location 55D1. Protein features are: Sodium:neurotransmitter symporter. Its molecular function is described by: neurotransmitter:sodium symporter activity; neurotransmitter transporter activity; transporter activity. It is involved in the biological process described with: transport; neurotransmitter transport. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable.
FBgn0032869	CG17470	-0.467439571	0.11785672	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17470 (FBgn0032869). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:20642306..20643244. It has the cytological map location 38D2. Its molecular function is unknown. It is involved in the biological process described with: mesoderm development. 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0035173	CG13907	-0.467212553	0.185085671	0.999936032	SLC16A14	SLC16A14;SLC16A9;SLC16A11;SLC16A4;SLC16A12;SLC16A6	high;moderate;low;low;low;low	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG13907 (FBgn0035173). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:877291..882013. It has the cytological map location 61D2-61D3. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain. Its molecular function is described by: monocarboxylic acid transmembrane transporter activity. It is involved in the biological process described with: monocarboxylic acid transport; transmembrane transport. 6 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: visible; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed during early pupal stages.
FBgn0260653	serp	-0.467025588	0.260928106	0.999936032	NA	NA	NA	NA	NA	NA	"The gene serpentine is referred to in FlyBase by the symbol Dmel\serp (CG32209, FBgn0260653). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:19700977..19708015. It has the cytological map location 76C2. Protein features are: Chitin binding domain; Glycoside hydrolase/deacetylase, beta/alpha-barrel; Low-density lipoprotein (LDL) receptor class A repeat; Low-density lipoprotein (LDL) receptor class A, conserved site; NodB homology domain. Its molecular function is described by: chitin binding; chitinase activity; chitin deacetylase activity. It is involved in the biological process described with: chitin catabolic process; regulation of tube length, open tracheal system; open tracheal system development; carbohydrate metabolic process. 19 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval tracheal system; embryonic/larval trachea; embryonic/first instar larval cuticle; cuticle; embryonic/larval dorsal trunk. The phenotypic classes of alleles include: viable; lethal; lethal - all die before end of pupal stage; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 06-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period.  "
FBgn0036622	CG4753	-0.466073169	0.180344207	0.999936032	AGPAT3	AGPAT4;AGPAT3;AGPAT5;LCLAT1	high;moderate;moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4753 (FBgn0036622). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3L:16378974..16381570. It has the cytological map location 72E4. Protein features are: Acyltransferase, C-terminal domain; Phospholipid/glycerol acyltransferase. Its molecular function is described by: transferase activity, transferring acyl groups. It is involved in the biological process described with: metabolic process. 11 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0004795	retn	-0.465976212	0.222998343	0.999936032	NA	ARID3A;ARID3C;ARID3B;ARID5A;ARID4B;ARID4A	high;moderate;moderate;low;low;low	DNA-binding with transcription factor activity(ARID)	NA	NA	"The gene retained is referred to in FlyBase by the symbol Dmel\retn (CG5403, FBgn0004795). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (all unique). Gene sequence location is 2R:23632610..23654820. It has the cytological map location 59F5. Protein features are: ARID DNA-binding domain; Armadillo-like helical; REKLES domain. Its molecular function is described by: transcription regulatory region sequence-specific DNA binding; DNA binding; transcription factor activity, sequence-specific DNA binding; RNA polymerase II regulatory region sequence-specific DNA binding; repressing transcription factor binding; transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding. It is involved in the biological process described with 14 unique terms, many of which group under: animal organ development; single-organism carbohydrate metabolic process; monosaccharide metabolic process; regulation of biological quality; regulation of transcription from RNA polymerase II promoter; movement of cell or subcellular component; pattern specification process; embryo development; reproduction; gamete generation; response to stimulus; gland development; small molecule metabolic process. 30 alleles are reported. The phenotypes of these alleles manifest in: neuron part; developing material anatomical entity; abdominal sensory neuron; alimentary canal; embryonic/larval hypodermal muscle; eo-type sensillum; cell projection; embryonic/larval nervous system; abdominal ventral multidendritic neuron; labial segment. The phenotypic classes of alleles include: behavior defective; increased mortality; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0259173	corn	-0.465304228	0.207940186	0.999936032	NA	SRRM1	low	NA	NA	NA	"The gene cornetto is referred to in FlyBase by the symbol Dmel\corn (CG42278, FBgn0259173). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 3L:7142991..7157073. It has the cytological map location 65E5. Its molecular function is described by: protein binding; microtubule binding. It is involved in the biological process described with: positive regulation of exocytosis. 19 alleles are reported. The phenotypes of these alleles manifest in: denticle belt; macrochaeta. The phenotypic classes of alleles include: viable; embryonic/larval segmentation phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0011763	Dp	-0.464563349	0.209385897	0.999936032	NA	TFDP2;TFDP1;TFDP3	high;high;moderate	DNA-binding with transcription factor activity(E2F_TDP)	NA	NA	"The gene DP transcription factor is referred to in FlyBase by the symbol Dmel\Dp (CG4654, FBgn0011763). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 2R:13222433..13228202. It has the cytological map location 49F10-49F11. Protein features are: E2F/DP family, winged-helix DNA-binding domain; Transcription factor DP; Transcription factor DP, C-terminal; Winged helix-turn-helix DNA-binding domain. Its molecular function is described by: transcription factor binding; protein binding; sequence-specific DNA binding; DNA binding; RNA polymerase II transcription factor activity, sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated; endomitotic cell cycle; positive regulation of gene expression; nurse cell apoptotic process; regulation of cell cycle; eggshell chorion gene amplification; positive regulation of nurse cell apoptotic process; oogenesis; intrinsic apoptotic signaling pathway in response to DNA damage; dorsal/ventral axis specification, ovarian follicular epithelium. 41 alleles are reported. The phenotypes of these alleles manifest in: female germline cell; chorion; female organism; external encapsulating structure; dorsal appendage; cell part; larval segment; embryonic/larval integumentary system; adult abdominal segment; dopaminergic neuron. The phenotypic classes of alleles include: locomotor behavior defective; partially lethal; female sterile; increased mortality; lethal - all die before end of larval stage; visible; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0033873	CG6337	-0.464074702	0.217764028	0.999936032	NA	CTSF;CTSW;CTSL;CTSS;CTSC;CTSB;CTSV;CTSZ;CTSK;CTSH	low;low;low;low;low;low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6337 (FBgn0033873). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:13833575..13835096. It has the cytological map location 50C6. Protein features are: Cathepsin propeptide inhibitor domain (I29); Peptidase C1A; Peptidase C1A, papain C-terminal. Its molecular function is described by: cysteine-type endopeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages.  "
FBgn0032494	CG5945	-0.463808959	0.20227482	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5945 (FBgn0032494). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:13239989..13241773. It has the cytological map location 34A11-34B1. Protein features are: Haemolymph juvenile hormone binding. Its molecular function is unknown. It is involved in the biological process described with: circadian rhythm; multicellular organism reproduction. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0011555	thetaTry	-0.463454773	0.181306453	0.999936032	NA	PRSS36;PRSS53;PRSS29P;HABP2;PRSS1;PRSS3	low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene ‘ŸTrypsin is referred to in FlyBase by the symbol Dmel\‘ŸTry (CG12385, FBgn0011555). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:11341714..11342760. It has the cytological map location 47F3-47F4. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period, in adult male stages.  "
FBgn0039857	RpL6	-0.463383929	0.182362697	0.999936032	RPL6	RPL6	high	NA	NA	NA	"The gene Ribosomal protein L6 is referred to in FlyBase by the symbol Dmel\RpL6 (CG11522, FBgn0039857). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:31594792..31596204. It has the cytological map location 100C7. Protein features are: 60S ribosomal protein L6E; Ribosomal protein L2 domain 2; Ribosomal protein L6, N-terminal; Translation protein SH3-like domain. Its molecular function is described by: RNA binding; structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; ribosomal large subunit assembly; translation. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal; some die during larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages.  "
FBgn0031022	CG12204	-0.462199253	0.223557226	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12204 (FBgn0031022). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:19493292..19494401. It has the cytological map location 18C7-18C8. Protein features are: WD40/YVTN repeat-like-containing domain. Its molecular function is described by: . It is involved in the biological process described with: . 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; flight defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0030834	CG8675	-0.462036881	0.222226316	0.999936032	C9orf85	C9orf85	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG8675 (FBgn0030834). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:17248372..17249502. It has the cytological map location 15F4. Protein features are: Protein of unknown function DUF2039. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 06-12 hour embryonic stages.
FBgn0003118	pnt	-0.4619084	0.225209983	0.999936032	NA	ETS1;ETS2;ETV2	high;moderate;moderate	DNA-binding with transcription factor activity(Ets)	NA	NA	"The gene pointed is referred to in FlyBase by the symbol Dmel\pnt (CG17077, FBgn0003118). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 3R:23290231..23346167. It has the cytological map location 94E10-94E13. Protein features are: Ets domain; Pointed domain; Sterile alpha motif/pointed domain; WD40/YVTN repeat-like-containing domain; Winged helix-turn-helix DNA-binding domain. Its molecular function is described by: sequence-specific DNA binding; transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding; RNA polymerase II transcription factor activity, sequence-specific DNA binding; protein binding; repressing transcription factor binding; transcription regulatory region DNA binding. It is involved in the biological process described with 36 unique terms, many of which group under: positive regulation of biological process; apoptotic process; nephrocyte differentiation; multi-organism process; transport; aging; muscle cell development; single-organism transport; regulation of response to stimulus; segmentation; Malpighian tubule development; epithelial cell migration. 119 alleles are reported. The phenotypes of these alleles manifest in: somatic stem cell; embryonic hindgut; embryonic/larval glial cell; presumptive embryonic/larval nervous system; presumptive embryonic/larval muscle system; secondary neuroblast; cellular process; tracheal metamere; non-membrane-bounded organelle; trunk mesoderm; gonad. The phenotypic classes of alleles include: increased mortality during development; phenotype; lethal; cell number defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0026372	RpL23A	-0.46067042	0.183922505	0.999936032	NA	RPL23A	high	NA	NA	NA	"The gene Ribosomal protein L23A is referred to in FlyBase by the symbol Dmel\RpL23A (CG7977, FBgn0026372). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:1667192..1668654. It has the cytological map location 62A10. Protein features are: Ribosomal protein L23/L15e core domain; Ribosomal protein L23/L25, N-terminal; Ribosomal protein L23/L25, conserved site; Ribosomal protein L25/L23. Its molecular function is described by: structural constituent of ribosome; RNA binding. It is involved in the biological process described with: cytoplasmic translation; ribosomal large subunit assembly; translation. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.  "
FBgn0263973	jv	-0.460503797	0.268624869	0.999936032	NA	NA	NA	NA	NA	NA	"The gene javelin is referred to in FlyBase by the symbol Dmel\jv (CG32397, FBgn0263973). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:6563197..6589479. It has the cytological map location 65B5. Its molecular function is unknown. It is involved in the biological process described with: parallel actin filament bundle assembly; chaeta morphogenesis. 13 alleles are reported. The phenotypes of these alleles manifest in: macrochaeta; microchaeta; denticle belt; nurse cell; posterior scutellar bristle; actin filament bundle. The phenotypic class of alleles includes: visible."
FBgn0046776	CR14033	-0.460439074	0.222455545	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CR14033 (FBgn0046776). It is a pseudogene_attribute from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2L:5242699..5244239. It has the cytological map location 25D2. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0014906	Hydr2	-0.45982546	0.198335754	0.999936032	ABHD2	ABHD2	high	NA	transmembrane protein	NA	"The gene ‘±/‘_ hydrolase2 is referred to in FlyBase by the symbol Dmel\Hydr2 (CG3488, FBgn0014906). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:3163645..3169462. It has the cytological map location 23D4. Protein features are: AB hydrolase 4 family; AB hydrolase 4, conserved site; Alpha/Beta hydrolase fold; Alpha/beta hydrolase fold-1. Its molecular function is described by: lipase activity; acylglycerol lipase activity. It is involved in the biological process described with: wing disc development; steroid hormone mediated signaling pathway; sperm capacitation; acylglycerol catabolic process; lipid metabolic process; chaeta development. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, in adult male stages.  "
FBgn0025687	LKRSDH	-0.459520515	0.273064063	0.999936032	NA	AASS	high	NA	NA	NA	"The gene Lysine ketoglutarate reductase/saccharopine dehydrogenase is referred to in FlyBase by the symbol Dmel\LKRSDH (CG7144, FBgn0025687). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:7791175..7795959. It has the cytological map location 28C4. Protein features are: Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal; Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain; NAD(P)-binding domain; Saccharopine dehydrogenase, C-terminal; Saccharopine dehydrogenase, NADP binding domain. Its molecular function is described by: saccharopine dehydrogenase activity. It is involved in the biological process described with: regulation of histone methylation; histone arginine methylation; generation of precursor metabolites and energy; lysine biosynthetic process via aminoadipic acid; oxidation-reduction process. 11 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0034920	CG5597	-0.459013972	0.206162663	0.999936032	NA	CADM2	low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5597 (FBgn0034920). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:23886973..23888777. It has the cytological map location 60A8. Protein features are: Immunoglobulin-like domain; Immunoglobulin-like fold. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0000556	eEF1alpha1	-0.458667783	0.184829309	0.999936032	NA	EEF1A2;EEF1A1;EEF1A1P5	high;moderate;moderate	NA	NA	NA	NA
FBgn0036433	CG9628	-0.458659707	0.250622859	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG9628 (FBgn0036433). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:14622796..14628174. It has the cytological map location 70E4-70E5. Its molecular function is described by: . It is involved in the biological process described with: . 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 06-18 hour embryonic stages.
FBgn0021764	sdk	-0.458525677	0.267017443	0.999936032	NA	SDK2;SDK1	high;moderate	NA	transmembrane protein	NA	"The gene sidekick is referred to in FlyBase by the symbol Dmel\sdk (CG5227, FBgn0021764). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (5 unique). Gene sequence location is X:686834..749496. It has the cytological map location 1C2-1C3. Protein features are: Fibronectin type III; Immunoglobulin I-set; Immunoglobulin V-set domain; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold. Its molecular function is unknown. It is involved in the biological process described with: pigment cell differentiation; negative regulation of photoreceptor cell differentiation; compound eye cone cell differentiation. 35 alleles are reported. The phenotypes of these alleles manifest in: cell; mechanosensory chaeta; pupa; neuron part; pigment cell; chaeta; imaginal disc epithelial cell; cell part; eo-type sensillum; dendritic tree; epithelium. The phenotypic classes of alleles include: neuroanatomy defective; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0033059	l(2)k09848	-0.458520197	0.214077809	0.999936032	NA	WDR74	high	NA	NA	NA	NA
FBgn0030757	CG9902	-0.458465262	0.133188259	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG9902 (FBgn0030757). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:16542124..16547520. It has the cytological map location 14E1. Its molecular function is unknown. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed during early pupal stages.
FBgn0004117	Tm2	-0.45842416	0.192668379	0.999936032	NA	TPM3;TPM2;TPM1;TPM4	high;high;moderate;high	NA	NA	NA	"The gene Tropomyosin 2 is referred to in FlyBase by the symbol Dmel\Tm2 (CG4843, FBgn0004117). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (2 unique). Gene sequence location is 3R:15310193..15315197. It has the cytological map location 88E13. Protein features are: Tropomyosin. Its molecular function is described by: actin binding; structural constituent of muscle; actin filament binding. It is involved in the biological process described with: heart development; actin filament organization; muscle contraction; positive regulation of sarcomere organization. 37 alleles are reported. The phenotypes of these alleles manifest in: Z disc; dorsal oblique muscle; skeletal muscle of thorax; sensory system; adult mesothoracic segment; lateral transverse muscle 1; embryonic myoblast; mesothoracic segment; lateral longitudinal muscle 1; non-connected functional system; myoblast; indirect flight muscle. The phenotypic classes of alleles include: some die during embryonic stage; increased mortality during development; phenotype; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of low expression.  Peak expression observed during late pupal stages.  "
FBgn0038294	Mf	-0.458404868	0.191179828	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Myofilin is referred to in FlyBase by the symbol Dmel\Mf (CG6803, FBgn0038294). It is a protein_coding_gene from Drosophila melanogaster. It has 17 annotated transcripts and 17 polypeptides (11 unique). Gene sequence location is 3R:15170625..15181510. It has the cytological map location 88E2. Protein features are: Myofilin. Its molecular function is unknown. It is involved in the biological process described with: wing disc development; chaeta development. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal - all die during P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0036152	CG6175	-0.458348542	0.260196451	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6175 (FBgn0036152). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:11287936..11295919. It has the cytological map location 68C1-68C2. Protein features are: MADF domain; WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. It is involved in the biological process described with: inter-male aggressive behavior; regulation of cell cycle. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal - majority die; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 and 12-18 hour embryonic stages, in adult female stages.  "
FBgn0051956	pgant4	-0.457404778	0.20067317	0.999936032	NA	GALNT10;GALNTL6;POC1B-GALNT4;GALNTL5;GALNT6;GALNT12;GALNT5;GALNT13;GALNT11;GALNT7;GALNT3;GALNT1;GALNT4	moderate;moderate;low;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene polypeptide GalNAc transferase 4 is referred to in FlyBase by the symbol Dmel\pgant4 (CG31956, FBgn0051956). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:3472603..3475338. It has the cytological map location 23F3. Protein features are: Glycosyltransferase 2-like; Nucleotide-diphospho-sugar transferases; Ricin B, lectin domain. Its molecular function is described by: polypeptide N-acetylgalactosaminyltransferase activity. It is involved in the biological process described with: positive regulation of secretion; secretory granule organization; oligosaccharide biosynthetic process; protein O-linked glycosylation. 11 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval proventriculus outer layer; secretory granule. The phenotypic classes of alleles include: lethal - all die during P-stage; viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0262515	VhaAC45	-0.456871822	0.187191467	0.999936032	NA	ATP6AP1;ATP6AP1L	high;moderate	NA	transmembrane protein	NA	"The gene Vacuolar H<sup>+</sup> ATPase AC45 accessory subunit is referred to in FlyBase by the symbol Dmel\VhaAC45 (CG8029, FBgn0262515). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:9207561..9209774. It has the cytological map location 45B4. Protein features are: ATPase, V1 complex, subunit S1. Its molecular function is described by: proton-transporting ATP synthase activity, rotational mechanism; proton-transporting ATPase activity, rotational mechanism. It is involved in the biological process described with: ATP hydrolysis coupled proton transport. 9 alleles are reported. The phenotypes of these alleles manifest in: sarcomere; Z disc. The phenotypic classes of alleles include: pain response defective; viable; lethal; lethal - all die during larval stage."
FBgn0015663	Dot	-0.456482655	0.211153976	0.999936032	NA	UGT1A3;UGT2B10;UGT1A1;UGT3A1;UGT8;UGT2B4;UGT2B15;UGT2B28;UGT2A2;UGT3A2;UGT2B17;UGT2B11;UGT2A3;UGT2B7	moderate;moderate;low;low;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene Dorothy is referred to in FlyBase by the symbol Dmel\Dot (CG2788, FBgn0015663). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:3619097..3621573. It has the cytological map location 24A1-24A2. Protein features are: UDP-glucuronosyl/UDP-glucosyltransferase. Its molecular function is described by: glucuronosyltransferase activity. It is involved in the biological process described with: metabolic process. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 06-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0015035	Cyp4e3	-0.4559467	0.277787259	0.999936032	NA	CYP4V2;CYP4A11;CYP4Z1;CYP4B1;CYP4F11;CYP4X1;CYP4F12;CYP4A22;CYP4F8;CYP46A1;CYP4F3;CYP4F2;CYP4F22	moderate;low;low;low;moderate;low;low;low;moderate;moderate;low;low;moderate	NA	transmembrane protein	NA	"The gene Cytochrome P450-4e3 is referred to in FlyBase by the symbol Dmel\Cyp4e3 (CG4105, FBgn0015035). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:9747839..9750071. It has the cytological map location 30C7. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Its molecular function is described by: heme binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; iron ion binding. It is involved in the biological process described with: oxidation-reduction process. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: short lived; viable; oxidative stress response defective; partially lethal - majority die; long lived; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed in adults stages of both sexes.  "
FBgn0039751	CG1983	-0.455503937	0.21676295	0.999936032	PROSC	PROSC	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1983 (FBgn0039751). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:30175786..30177700. It has the cytological map location 99E1. Protein features are: Alanine racemase, N-terminal; PLP-binding barrel; Pyridoxal phosphate homeostasis protein. Its molecular function is described by: pyridoxal phosphate binding. It is involved in the biological process described with: . 4 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: lethal; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, in adult female stages.  "
FBgn0261258	rgn	-0.4543027	0.227636498	0.999936032	NA	REG1A	high	NA	NA	NA	"The gene regeneration is referred to in FlyBase by the symbol Dmel\rgn (CG6014, FBgn0261258). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3L:21382501..21424416. It has the cytological map location 78C9-78D1. Protein features are: C-type lectin fold; C-type lectin-like; C-type lectin-like/link domain. Its molecular function is described by: carbohydrate binding. It is involved in the biological process described with: tissue regeneration. 21 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal - majority die; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0261602	RpL8	-0.454040374	0.189162096	0.999936032	NA	RPL8;MIR6850	high;moderate	NA	NA	NA	"The gene Ribosomal protein L8 is referred to in FlyBase by the symbol Dmel\RpL8 (CG1263, FBgn0261602). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:2587456..2588883. It has the cytological map location 62E7. Protein features are: Nucleic acid-binding, OB-fold; Ribosomal Proteins L2, RNA binding domain; Ribosomal protein L2; Ribosomal protein L2 domain 2; Ribosomal protein L2, C-terminal; Ribosomal protein L2, conserved site; Ribosomal protein L2, domain 3; Translation protein SH3-like domain. Its molecular function is described by: structural constituent of ribosome; RNA binding. It is involved in the biological process described with: translation; insulin receptor signaling pathway; cytoplasmic translation; regulation of cell size; compound eye development. 9 alleles are reported. The phenotypes of these alleles manifest in: ommatidium; Z disc; eye; wing margin bristle; sarcomere. The phenotypic classes of alleles include: lethal; increased mortality; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0261592	RpS6	-0.454011156	0.190412983	0.999936032	NA	RPS6	high	NA	NA	NA	"The gene Ribosomal protein S6 is referred to in FlyBase by the symbol Dmel\RpS6 (CG10944, FBgn0261592). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:7899624..7901331. It has the cytological map location 7B-7C2. Protein features are: Ribosomal protein S6, eukaryotic; Ribosomal protein S6e; Ribosomal protein S6e, conserved site. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: immune response; rRNA processing; ribosomal small subunit biogenesis; cytoplasmic translation; translation. 16 alleles are reported. The phenotypes of these alleles manifest in: prothoracic gland; macrophage; eye; embryonic/larval lymph gland. The phenotypic classes of alleles include: increased mortality during development; phenotype; visible; developmental rate defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages.  "
FBgn0029755	Sas10	-0.45393547	0.218555316	0.999936032	NA	UTP3	high	NA	NA	NA	"The gene Something about silencing 10 is referred to in FlyBase by the symbol Dmel\Sas10 (CG4202, FBgn0029755). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:5317409..5319071. It has the cytological map location 4F5. Protein features are: Sas10 C-terminal domain; Sas10/Utp3/C1D. Its molecular function is unknown. It is involved in the biological process described with: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). 9 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; embryonic/larval neuroblast; ganglion mother cell; trichogen cell. The phenotypic classes of alleles include: viable; increased mortality during development; phenotype; lethal - all die during P-stage; increased mortality; some die during P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0034299	CG5757	-0.453707406	0.237596254	0.999936032	DTYMK	DTYMK	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5757 (FBgn0034299). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:18093723..18094900. It has the cytological map location 55B4. Protein features are: P-loop containing nucleoside triphosphate hydrolase; Thymidylate kinase; Thymidylate kinase, conserved site. Its molecular function is described by: ATP binding; uridylate kinase activity; thymidylate kinase activity. It is involved in the biological process described with: dUDP biosynthetic process; dTTP biosynthetic process; dTDP biosynthetic process. 11 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: pain response defective; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0037570	CG11693	-0.45331452	0.174129074	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG11693 (FBgn0037570). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:8308881..8310778. It has the cytological map location 84F11. Protein features are: Protein of unknown function DUF745. Its molecular function is described by: . It is involved in the biological process described with: developmental process. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages.
FBgn0020762	Atet	-0.452903127	0.241547367	0.999936032	ABCG4	ABCG4;ABCG1	high;moderate	NA	transmembrane protein	NA	"The gene ABC transporter expressed in trachea is referred to in FlyBase by the symbol Dmel\Atet (CG2969, FBgn0020762). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 2L:4333913..4345776. It has the cytological map location 24E1. Protein features are: AAA+ ATPase domain; ABC transporter, conserved site; ABC transporter-like; ABC-2 type transporter; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: cholesterol transporter activity; ATP binding; ATPase activity, coupled to transmembrane movement of substances; sterol-transporting ATPase activity. It is involved in the biological process described with: transmembrane transport. 12 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval somatic muscle; Z disc; trichogen cell; sarcomere; embryonic/larval neuroblast; ganglion mother cell; mesothoracic tergum. The phenotypic classes of alleles include: some die during larval stage; increased mortality; developmental rate defective; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during early pupal stages.  "
FBgn0010497	dmGlut	-0.452705223	0.195663583	0.999936032	NA	SLC17A5;SLC17A3;SLC17A6;SLC17A8;SLC17A7;SLC17A4;SLC17A2;SLC17A1	moderate;high;moderate;moderate;moderate;low;low;low	NA	transmembrane protein	NA	"The gene Dietary and metabolic glutamate transporter is referred to in FlyBase by the symbol Dmel\dmGlut (CG5304, FBgn0010497). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:12027438..12034122. It has the cytological map location 33B9. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain. Its molecular function is described by: sodium-dependent phosphate transmembrane transporter activity; high-affinity glutamate transmembrane transporter activity. It is involved in the biological process described with: L-glutamate import; glutamine metabolic process; mitochondrion organization; sodium-dependent phosphate transport; transmembrane transport. 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0030005	CG2120	-0.452476435	0.239698492	0.999936032	NA	ZNF239;ZNF234;ZNF227;ZNF214;ZNF235	high;high;high;high;high	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG2120 (FBgn0030005). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:8135824..8137046. It has the cytological map location 7D14. Protein features are: Zinc finger C2H2-type. Its molecular function is described by: nucleic acid binding. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages.
FBgn0033638	CG9005	-0.45156294	0.220362984	0.999936032	NA	FAM214A;FAM214B	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9005 (FBgn0033638). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:11619479..11640941. It has the cytological map location 48A3-48B2. Protein features are: Domain of unknown function DUF4210; Protein FAM214/SPAC3H8.04, C-terminal. Its molecular function is described by: . It is involved in the biological process described with: response to endoplasmic reticulum stress. 13 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: short lived; body color defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0036365	cmb	-0.45155439	0.266267325	0.999936032	NA	PCM1	low	NA	NA	NA	"The gene combover is referred to in FlyBase by the symbol Dmel\cmb (CG10732, FBgn0036365). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 3L:13442594..13449245. It has the cytological map location 70B1. Its molecular function is described by: protein binding. It is involved in the biological process described with: imaginal disc-derived wing hair organization. 6 alleles are reported. The phenotype of these alleles manifest in: wing hair. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed in adult male stages.  "
FBgn0062928	hpRNA:CR33940	-0.451521422	0.220871634	0.999936032	NA	NA	NA	NA	NA	NA	"The gene hairpin RNA:CR33940 is referred to in FlyBase by the symbol Dmel\hpRNA:CR33940 (CR33940, FBgn0062928). It is a non_protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts. Gene sequence location is 3L:19486745..19488439. It has the cytological map location 76B4. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0051826	CG31826	-0.451400277	0.261862322	0.999936032	NA	TTPAL	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31826 (FBgn0051826). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:15771263..15773113. It has the cytological map location 35D4. Protein features are: CRAL-TRIO lipid binding domain; CRAL/TRIO, N-terminal domain; Cellular retinaldehyde binding/alpha-tocopherol transport. Its molecular function is described by: transporter activity. It is involved in the biological process described with: transport. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed in adult male stages.  "
FBgn0027334	l(1)G0004	-0.451385806	0.209994279	0.999936032	NA	PNO1	high	NA	NA	NA	"The gene lethal (1) G0004 is referred to in FlyBase by the symbol Dmel\l(1)G0004 (CG11738, FBgn0027334). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:20391447..20392401. It has the cytological map location 19C5-19C6. Protein features are: K Homology domain; K Homology domain, type 1. Its molecular function is described by: RNA binding. The biological processes in which it is involved are not known. 6 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: phenotype; increased mortality during development; increased mortality; some die during P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0033679	CG8888	-0.45134595	0.247124134	0.999936032	NA	BDH1;HSD11B2;RDH16;HSD17B2;SDR9C7;HSD17B6;DHRS9	high;moderate;moderate;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8888 (FBgn0033679). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:12064565..12079543. It has the cytological map location 48D8-48E1. Protein features are: NAD(P)-binding domain; Short-chain dehydrogenase/reductase SDR. Its molecular function is unknown. The biological processes in which it is involved are not known. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal; short lived; fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period.  "
FBgn0015229	glec	-0.450793273	0.226104247	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene gliolectin is referred to in FlyBase by the symbol Dmel\glec (CG6575, FBgn0015229). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:21850694..21856266. It has the cytological map location 93F14. Its molecular function is described by: carbohydrate binding. It is involved in the biological process described with: heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; cell adhesion; nervous system development. 23 alleles are reported. The phenotypes of these alleles manifest in: macrochaeta; scutellar bristle; germline cell; trichogen cell. The phenotypic classes of alleles include: visible; viable; lethal; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 06-18 hour embryonic stages, at stages throughout the pupal period.  "
FBgn0038839	Ktl	-0.450570846	0.254289886	0.999936032	NA	KCTD12;KCTD8;KCTD16	high;high;high	NA	transmembrane protein	NA	"The gene Kctd12-like is referred to in FlyBase by the symbol Dmel\Ktl (CG10830, FBgn0038839). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:20894452..20897320. It has the cytological map location 93A2. Protein features are: BTB/POZ domain; Potassium channel tetramerisation-type BTB domain; SKP1/BTB/POZ domain. Its molecular function is unknown. It is involved in the biological process described with: sleep; male courtship behavior; protein homooligomerization; inter-male aggressive behavior; negative regulation of locomotion involved in locomotory behavior. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: behavior defective; locomotor behavior defective; sleep defective; courtship behavior defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages.  "
FBgn0015571	alpha-Est3	-0.45029905	0.211160443	0.999936032	NA	CES4A;CES2;NLGN2;CES5A;CES1;CEL;NLGN4X;NLGN1;NLGN3;NLGN4Y;CES3	low;low;low;low;low;low;low;low;low;low;low	NA	NA	NA	"The gene ‘±-Esterase-3 is referred to in FlyBase by the symbol Dmel\‘±-Est3 (CG1257, FBgn0015571). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3R:7538972..7541631. It has the cytological map location 84D9. Protein features are: Alpha/Beta hydrolase fold; Carboxylesterase, type B. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed in adult male stages.  "
FBgn0033775	Cyp9h1	-0.450236883	0.204818277	0.999936032	CYP3A5	CYP3A5;TBXAS1;CYP3A43;CYP3A4;CYP3A7-CYP3A51P;CYP3A7	moderate;moderate;moderate;moderate;moderate;low	NA	transmembrane protein	NA	"The gene Cyp9h1 is referred to in FlyBase by the symbol Dmel\Cyp9h1 (CG17577, FBgn0033775). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:12840813..12842558. It has the cytological map location 49D4. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Its molecular function is described by: oxidoreductase activity; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; heme binding. It is involved in the biological process described with: oxidation-reduction process. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during early pupal stages.  "
FBgn0032224	Sps2	-0.450190053	0.25152166	0.999936032	NA	SEPHS1;SEPHS2	moderate;moderate	NA	NA	NA	"The gene Selenophosphate synthetase 2 is referred to in FlyBase by the symbol Dmel\Sps2 (CG5025, FBgn0032224). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:10342594..10344223. It has the cytological map location 31D9. Protein features are: AIR synthase-related protein, C-terminal domain; PurM-like, N-terminal domain; Selenophosphate synthetase; Selenophosphate synthetase, class I. Its molecular function is described by: ATP binding; purine nucleotide binding; selenide, water dikinase activity; catalytic activity. It is involved in the biological process described with: selenocysteine biosynthetic process. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: locomotor behavior defective; viable; song defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0000533	ea	-0.450160556	0.281790997	0.999936032	NA	KLK1	low	Maybe TF	NA	NA	"The gene easter is referred to in FlyBase by the symbol Dmel\ea (CG4920, FBgn0000533). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:15328729..15330408. It has the cytological map location 88F1. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Proteinase, regulatory CLIP domain; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity; endopeptidase activity. It is involved in the biological process described with: Toll signaling pathway; dorsal/ventral axis specification; proteolysis; dorsal/ventral pattern formation; maternal specification of dorsal/ventral axis, oocyte, germ-line encoded; ventral furrow formation. 73 alleles are reported. The phenotypes of these alleles manifest in: embryo; gastrula embryo; trichome field; abdominal segment 8; dorsal fold; larval ocular segment; mitotic domain; epithelial tube; developing material anatomical entity; embryonic epidermis; tracheal system. The phenotypic classes of alleles include: increased mortality during development; phenotype; fertile; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0039737	CG7920	-0.448903695	0.196408907	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7920 (FBgn0039737). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:30010476..30015284. It has the cytological map location 99D1. Protein features are: Acetyl-CoA hydrolase/transferase; Acetyl-CoA hydrolase/transferase C-terminal domain. Its molecular function is described by: catalytic activity. It is involved in the biological process described with: acetyl-CoA metabolic process. 13 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; embryonic/larval neuroblast; mesothoracic tergum. The phenotypic classes of alleles include: flightless; increased mortality; visible; phenotype; increased mortality during development; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0028539	CG31731	-0.448864853	0.231264303	0.999936032	NA	ABCA2;ABCA3;ABCA12;ABCA5;ABCA10;ABCA4;ABCA13;ABCA1;ABCA6;ABCA8;ABCA7;ABCA9	high;low;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31731 (FBgn0028539). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:13784084..13790562. It has the cytological map location 34D1. Protein features are: AAA+ ATPase domain; ABC transporter A, ABCA; ABC transporter, conserved site; ABC transporter-like; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: ATPase activity, coupled to transmembrane movement of substances; transporter activity; ATP binding. It is involved in the biological process described with: transport; lipid transport. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; some die during pupal stage; fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0030403	CG1824	-0.448817703	0.20672849	0.999936032	ABCB8	ABCB8;ABCB10	high;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1824 (FBgn0030403). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:12592555..12595624. It has the cytological map location 11B2. Protein features are: AAA+ ATPase domain; ABC transporter type 1, transmembrane domain; ABC transporter, conserved site; ABC transporter-like; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: ATP binding; transporter activity; ATPase activity, coupled to transmembrane movement of substances. It is involved in the biological process described with: transmembrane transport. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0030837	CG8661	-0.448708122	0.194643557	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG8661 (FBgn0030837). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:17283762..17284500. It has the cytological map location 15F7. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. The phenotypic class of allele includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the larval period.
FBgn0085282	CG34253	-0.448678464	0.199520263	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG34253 (FBgn0085282). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:18086674..18087320. It has the cytological map location 75B7. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during late larval stages, at stages throughout the pupal period.  "
FBgn0032209	Hand	-0.448150227	0.241803357	0.999936032	HAND1	HAND2;HAND1	high;moderate	DNA-binding with transcription factor activity(HLH)	NA	NA	"The gene Hand is referred to in FlyBase by the symbol Dmel\Hand (CG18144, FBgn0032209). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:10292679..10295385. It has the cytological map location 31C6-31C7. Protein features are: Myc-type, basic helix-loop-helix (bHLH) domain. Its molecular function is described by: transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding; protein dimerization activity; transcription factor activity, sequence-specific DNA binding. It is involved in the biological process described with: positive regulation of transcription elongation from RNA polymerase II promoter; hemopoiesis; larval heart development; negative regulation of apoptotic process; embryonic heart tube development; regulation of transcription, DNA-templated; dendrite morphogenesis. 17 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval hemocoel; adult thoracic segment; developing material anatomical entity; somatic cell; adult tagma; crop; multidendritic neuron; organism subdivision; integumentary system; embryo; embryonic/larval heart; embryonic/larval lymph gland; circulatory system primordium. The phenotypic classes of alleles include: behavior defective; visible; increased mortality during development; phenotype; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 06-24 hour embryonic stages, during early pupal stages.  "
FBgn0002778	mnd	-0.447541362	0.28676727	0.999936032	NA	SLC7A7;SLC7A6;SLC7A8;SLC7A5;SLC7A10;SLC7A9;SLC7A11	high;moderate;moderate;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene minidiscs is referred to in FlyBase by the symbol Dmel\mnd (CG3297, FBgn0002778). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3L:14985100..14991667. It has the cytological map location 71A4-71B1. Protein features are: Amino acid/polyamine transporter I. Its molecular function is described by: amino acid transmembrane transporter activity; antiporter activity; L-amino acid transmembrane transporter activity. It is involved in the biological process described with: amino acid transmembrane transport; leucine import; sleep; amino acid transport. 53 alleles are reported. The phenotypes of these alleles manifest in: prepupa; larval thorax; pupa; embryo; multicellular structure; larval metathoracic segment; adult; thoracic segment; head; adipose system. The phenotypic classes of alleles include: some die during larval stage; wild-type; lethal; fertile; lethal - all die before end of larval stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.  "
FBgn0028737	eEF1beta	-0.446709773	0.196690444	0.999936032	NA	EEF1B2;EEF1D	high;moderate	NA	NA	NA	"The gene eukaryotic translation elongation factor 1 beta is referred to in FlyBase by the symbol Dmel\eEF1‘_ (CG6341, FBgn0028737). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:16868222..16869280. It has the cytological map location 53D14. Protein features are: Elongation factor 1 beta central acidic region, eukaryote; Glutathione S-transferase, C-terminal-like; Translation elongation factor EF1B, beta/delta chains, conserved site; Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain; Translation elongation factor EF1B/ribosomal protein S6. Its molecular function is described by: translation elongation factor activity. It is involved in the biological process described with: translational elongation. 5 alleles are reported. The phenotypes of these alleles manifest in: scutellar bristle; dorsocentral bristle. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; some die during pupal stage; visible; viable; lethal - all die during P-stage; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0033246	ACC	-0.44667698	0.227117542	0.999936032	NA	ACACA;ACACB	high;moderate	NA	transmembrane protein	NA	"The gene Acetyl-CoA carboxylase is referred to in FlyBase by the symbol Dmel\ACC (CG11198, FBgn0033246). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (3 unique). Gene sequence location is 2R:7974115..7991862. It has the cytological map location 44A1-44A2. Protein features are: ATP-grasp fold; ATP-grasp fold, subdomain 1; Acetyl-CoA carboxylase; Acetyl-CoA carboxylase, central domain; Acetyl-coenzyme A carboxyltransferase, C-terminal; Acetyl-coenzyme A carboxyltransferase, N-terminal; Biotin carboxylase, C-terminal; Biotin carboxylase-like, N-terminal domain; Biotin carboxylation domain; Biotin-binding site; Biotin/lipoyl attachment; Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain; ClpP/crotonase-like domain; Pre-ATP-grasp domain; Rudiment single hybrid motif; Single hybrid motif. Its molecular function is described by: ATP binding; metal ion binding; biotin carboxylase activity; acetyl-CoA carboxylase activity. It is involved in the biological process described with: glycogen metabolic process; fatty acid biosynthetic process; cell morphogenesis; regulation of cellular protein localization; response to sucrose; triglyceride biosynthetic process; cellular response to sucrose stimulus; regulation of Notch signaling pathway; regulation of Wnt signaling pathway; regulation of growth. 11 alleles are reported. The phenotypes of these alleles manifest in: wing; embryonic/larval tracheal system; embryonic/larval trachea; wing disc; lipid particle; adult oenocyte; embryonic/larval spiracle; embryonic/larval oenocyte; embryonic/larval fat body; embryonic/larval brain. The phenotypic classes of alleles include: behavior defective; visible; phenotype; stress response defective; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0025117	und	-0.446569103	0.202878699	0.999936032	NA	METAP2	high	NA	NA	NA	NA
FBgn0001098	Gdh	-0.446329694	0.20141975	0.999936032	GLUD1	GLUD1;GLUD2	high;moderate	NA	NA	NA	"The gene Glutamate dehydrogenase is referred to in FlyBase by the symbol Dmel\Gdh (CG5320, FBgn0001098). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 3R:23935958..23943101. It has the cytological map location 95C13-95D1. Protein features are: Glutamate dehydrogenase; Glutamate/phenylalanine/leucine/valine dehydrogenase; Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain; Leu/Phe/Val dehydrogenases active site; NAD(P) binding domain of glutamate dehydrogenase; NAD(P)-binding domain. Its molecular function is described by: identical protein binding; glutamate dehydrogenase [NAD(P)+] activity; glutamate dehydrogenase (NAD+) activity. It is involved in the biological process described with: glutamate catabolic process to 2-oxoglutarate; NADH oxidation; glutamate metabolic process. 21 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; starvation stress response defective; short lived; fertile; electrophoretic variant. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0015527	peng	-0.446319877	0.220585445	0.999936032	NA	PUM3	high	NA	NA	NA	"The gene penguin is referred to in FlyBase by the symbol Dmel\peng (CG1685, FBgn0015527). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:21346503..21349843. It has the cytological map location 19F5. Protein features are: Armadillo-like helical; Armadillo-type fold; CPL domain; Pumilio RNA-binding repeat; Pumilio homology domain. Its molecular function is described by: mRNA binding. It is involved in the biological process described with: regulation of translation; apposition of dorsal and ventral imaginal disc-derived wing surfaces. 7 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0040382	CG5273	-0.446162107	0.232744145	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5273 (FBgn0040382). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is X:759594..761939. It has the cytological map location 1C4. Protein features are: Protein of unknown function DUF4813. Its molecular function is unknown. It is involved in the biological process described with: regulation of circadian rhythm. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable; locomotor rhythm defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in adult male stages.  "
FBgn0032433	Oatp33Ea	-0.445664652	0.200175557	0.999936032	NA	SLCO2B1;SLCO2A1;SLCO5A1;SLCO1C1;SLCO1A2;SLCO1B3;SLCO1B7;SLCO1B1;SLCO3A1;SLCO6A1;SLCO4C1	moderate;high;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene Organic anion transporting polypeptide 33Ea is referred to in FlyBase by the symbol Dmel\Oatp33Ea (CG5427, FBgn0032433). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:12441401..12445924. It has the cytological map location 33E5. Protein features are: Kazal domain; Major facilitator superfamily domain; Organic anion transporter polypeptide OATP. Its molecular function is described by: transmembrane transporter activity; active transmembrane transporter activity; sodium-independent organic anion transmembrane transporter activity. It is involved in the biological process described with: organic substance transport; sodium-independent organic anion transport. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; flightless; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0003978	vls	-0.445120384	0.251538892	0.999936032	NA	WDR77	high	NA	NA	NA	"The gene valois is referred to in FlyBase by the symbol Dmel\vls (CG10728, FBgn0003978). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:20064261..20065679. It has the cytological map location 38B2. Protein features are: WD40 repeat; WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. It is involved in the biological process described with: cellularization; pole plasm assembly; embryonic pattern specification. 15 alleles are reported. The phenotypes of these alleles manifest in: embryonic tagma; dorsal closure embryo; oocyte nucleus; cell part; embryonic/larval cuticle; abdominal segment 1; abdominal segment 10; blastoderm embryo; pole plasm; larva. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; phenotype; increased mortality during development; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0052218	CR32218	-0.444429154	0.247377945	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CR32218 (FBgn0052218).The gene has a gene model, but the supporting evidence is inconclusive. It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3L:19895216..19896391. It has the cytological map location 76D3. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. No phenotypic class data is available."
FBgn0086676	spin	-0.44418719	0.217213729	0.999936032	NA	SPNS1;SPNS2;SPNS3	high;moderate;moderate	NA	transmembrane protein	NA	"The gene spinster is referred to in FlyBase by the symbol Dmel\spin (CG8428, FBgn0086676). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (all unique). Gene sequence location is 2R:16124981..16138238. It has the cytological map location 52F5-52E. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain. Its molecular function is described by: sphingolipid transporter activity. It is involved in the biological process described with 22 unique terms, many of which group under: transport; locomotion; endosome to lysosome transport; larval central nervous system remodeling; response to external stimulus; regulation of decapentaplegic signaling pathway; cellular response to external stimulus; anatomical structure morphogenesis; vacuole organization; courtship behavior. 70 alleles are reported. The phenotypes of these alleles manifest in: endomembrane system; synapse; dorsal multidendritic neuron ddaE; neuron part; adult central nervous system; chorion; egg; cell; PNS glial cell; external sensory organ; neuromuscular junction; adult thoracic segment; dorsal appendage; dendritic tree; presumptive embryonic/larval peripheral nervous system. The phenotypic classes of alleles include: phenotype; mating defective; lethal - all die before end of first instar larval stage; behavior defective; cell death defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, in adult male stages.  "
FBgn0039667	CG2010	-0.444139361	0.256589305	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG2010 (FBgn0039667). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:29494782..29498923. It has the cytological map location 99B1. Protein features are: F-box domain; Leucine-rich repeat domain, L domain-like. Its molecular function is described by: ubiquitin-protein transferase activity. It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. 9 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0038683	CG11779	-0.444073795	0.224515155	0.999936032	NA	TIMM44	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG11779 (FBgn0038683). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:19154097..19159878. It has the cytological map location 91F4. Protein features are: Mitochondrial import inner membrane translocase subunit Tim44; NTF2-like domain; Tim44-like domain. Its molecular function is described by: chaperone binding; P-P-bond-hydrolysis-driven protein transmembrane transporter activity. It is involved in the biological process described with: protein targeting to mitochondrion; protein import into mitochondrial matrix; cellular response to hypoxia. 15 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; eye; trichogen cell. The phenotypic classes of alleles include: some die during pupal stage; partially lethal - majority die; viable; visible; fertile; lethal - all die during larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed in adult male stages.
FBgn0039764	CG15535	-0.443694581	0.256667113	0.999936032	NA	CCDC59	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG15535 (FBgn0039764). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:30423032..30423929. It has the cytological map location 99F4. Protein features are: Fyv7/TAP26. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages.
FBgn0023507	D2hgdh	-0.443491094	0.20200168	0.999936032	NA	D2HGDH	high	NA	NA	NA	"The gene D-2-hydroxyglutaric acid dehydrogenase is referred to in FlyBase by the symbol Dmel\D2hgdh (CG3835, FBgn0023507). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is X:2141489..2144937. It has the cytological map location 2D4. Protein features are: CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2; FAD linked oxidase, N-terminal; FAD-binding, type 2; FAD-binding, type 2, subdomain 1; FAD-linked oxidase, C-terminal; FAD-linked oxidase-like, C-terminal; Vanillyl-alcohol oxidase, C-terminal subdomain 2. Its molecular function is described by: (R)-2-hydroxyglutarate dehydrogenase activity; FAD binding; D-lactate dehydrogenase (cytochrome) activity. It is involved in the biological process described with: oxidation-reduction process; respiratory electron transport chain; lactate oxidation. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed during early larval stages, in adult male stages.  "
FBgn0004362	HmgD	-0.443259266	0.231547218	0.999936032	NA	HMGB2	moderate	DNA-binding with transcription factor activity(HMG_box)	NA	NA	"The gene High mobility group protein D is referred to in FlyBase by the symbol Dmel\HmgD (CG17950, FBgn0004362). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2R:21701458..21716727. It has the cytological map location 57F9-57F10. Protein features are: High mobility group box domain. Its molecular function is described by: DNA binding, bending; DNA binding; AT DNA binding. It is involved in the biological process described with: chromatin organization; dendrite morphogenesis; muscle organ development. 50 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; rhabdomere R7. The phenotypic classes of alleles include: lethal; increased mortality; phenotype; increased mortality during development; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0261451	trol	-0.443243018	0.252184692	0.999936032	NA	HSPG2;EGFLAM	high;low	NA	NA	NA	NA
FBgn0019925	Surf4	-0.443076153	0.205494175	0.999936032	SURF4	SURF4	high	NA	transmembrane protein	NA	"The gene Surfeit 4 is referred to in FlyBase by the symbol Dmel\Surf4 (CG6202, FBgn0019925). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:15343653..15346176. It has the cytological map location 88F1. Protein features are: Surfeit locus 4. Its molecular function is unknown. It is involved in the biological process described with: lateral inhibition. 7 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; chaeta. The phenotypic classes of alleles include: increased mortality during development; phenotype; visible; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 06-18 hour embryonic stages, during early larval stages.  "
FBgn0037369	CG2100	-0.442876021	0.273757574	0.999936032	TRNT1	TRNT1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG2100 (FBgn0037369). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:5734698..5736355. It has the cytological map location 83C1. Protein features are: Poly A polymerase, head domain; tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain. Its molecular function is described by: RNA binding; nucleotidyltransferase activity. It is involved in the biological process described with: RNA processing. 5 alleles are reported. The phenotype of these alleles manifest in: ganglion mother cell. The phenotypic classes of alleles include: viable; lethal; some die during pupal stage; pain response defective; lethal - all die before end of pupal stage; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0086698	frtz	-0.442242991	0.289639162	0.999936032	NA	WDPCP	high	NA	NA	NA	"The gene fritz is referred to in FlyBase by the symbol Dmel\frtz (CG17657, FBgn0086698). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:1711302..1715851. It has the cytological map location 22B1. Protein features are: WD repeat-containing and planar cell polarity effector protein Fritz; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. It is involved in the biological process described with: imaginal disc-derived wing hair site selection. 26 alleles are reported. The phenotypes of these alleles manifest in: array of sensilla rows; denticle belt; abdominal sternite bristle; array of rows; adult sense organ; denticle field; abdomen; embryonic/larval integumentary system; sensory system; larva. The phenotypic classes of alleles include: fertile; short lived; viable; visible; planar polarity defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0262844	CG43208	-0.442111812	0.283770996	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG43208 (FBgn0262844). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:13303426..13303856. It has the cytological map location 87E5. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported.
FBgn0040383	CG5254	-0.441989231	0.203747863	0.999936032	NA	SLC25A21	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG5254 (FBgn0040383). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:750347..758719. It has the cytological map location 1C3-1C4. Protein features are: Mitochondrial carrier domain; Mitochondrial substrate/solute carrier. Its molecular function is described by: dicarboxylic acid transmembrane transporter activity. It is involved in the biological process described with: mitochondrial transport; autophagic cell death; dicarboxylic acid transport; salivary gland cell autophagic cell death. 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during early pupal stages.
FBgn0039419	CG12290	-0.441801507	0.234385123	0.999936032	NA	HRH3;HRH4	low;low	NA	transmembrane protein	GPCR	"This gene is referred to in FlyBase by the symbol Dmel\CG12290 (FBgn0039419). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:26230248..26234700. It has the cytological map location 97A6. Protein features are: G protein-coupled receptor, rhodopsin-like; GPCR, rhodopsin-like, 7TM. Its molecular function is described by: histamine receptor activity; G-protein coupled receptor activity. It is involved in the biological process described with: G-protein coupled receptor signaling pathway. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed during early pupal stages.  "
FBgn0028978	trbl	-0.441750597	0.237497814	0.999936032	NA	TRIB2;TRIB3;TRIB1	high;moderate;moderate	NA	NA	NA	"The gene tribbles is referred to in FlyBase by the symbol Dmel\trbl (CG5408, FBgn0028978). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:20396288..20401609. It has the cytological map location 77C1. Protein features are: Protein kinase domain; Protein kinase-like domain; Pseudokinase tribbles family/serine-threonine-protein kinase 40. Its molecular function is described by: protein heterodimerization activity; ATP binding; mitogen-activated protein kinase kinase binding; protein homodimerization activity. It is involved in the biological process described with: negative regulation of mitotic nuclear division; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; negative regulation of insulin receptor signaling pathway; ventral furrow formation; regulation of MAP kinase activity; gastrulation; regulation of cell cycle. 44 alleles are reported. The phenotypes of these alleles manifest in: microchaeta; mitotic cell cycle; mesoderm anlage; compartment; spermatogonium; mitotic domain 2; cell cycle; mitotic domain 3; mitotic domain 10; trichogen cell; single-organism process. The phenotypic classes of alleles include: increased mortality; memory defective; phenotype; female semi-sterile; cell size defective; wild-type. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0014396	tim	-0.441652831	0.209735085	0.999936032	NA	TIMELESS	moderate	Maybe TF	NA	NA	"The gene timeless is referred to in FlyBase by the symbol Dmel\tim (CG3234, FBgn0014396). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (8 unique). Gene sequence location is 2L:3493986..3508119. It has the cytological map location 23F6. Protein features are: Timeless protein. Its molecular function is described by: protein heterodimerization activity; transcription factor binding; protein binding. It is involved in the biological process described with 22 unique terms, many of which group under: regulation of protein targeting; locomotory behavior; multicellular organism reproduction; eclosion rhythm; phototaxis; regulation of biosynthetic process; photoperiodism; cellular response to abiotic stimulus; regulation of binding; regulation of endocytosis. 75 alleles are reported. The phenotypes of these alleles manifest in: indirect flight muscle motor neuron MN5; adult heart; Malpighian tubule; posterior adult hindgut. The phenotypic classes of alleles include: circadian behavior defective; circadian rhythm defective; phenotype; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed in adults stages of both sexes.  "
FBgn0030572	mRpS25	-0.441441383	0.227588811	0.999936032	MRPS25	MRPS25	high	NA	NA	NA	"The gene mitochondrial ribosomal protein S25 is referred to in FlyBase by the symbol Dmel\mRpS25 (CG14413, FBgn0030572). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:14582136..14582982. It has the cytological map location 12F1. Protein features are: Ribosomal protein/NADH dehydrogenase domain; Thioredoxin-like fold. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation; translation. 6 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 06-18 hour embryonic stages, during early larval stages, during late pupal stages.  "
FBgn0261995	CG42813	-0.441416886	0.2041849	0.999936032	NA	NUDT14	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG42813 (FBgn0261995). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:27227070..27228561. It has the cytological map location 97E10. Protein features are: NUDIX hydrolase domain; NUDIX hydrolase domain-like; Nucleoside diphosphate pyrophosphatase. Its molecular function is described by: hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; metal ion binding. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available."
FBgn0038552	CG18012	-0.441247158	0.209280861	0.999936032	ALG1	ALG1;ALG1L;ALG1L2	high;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG18012 (FBgn0038552). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:17809401..17811134. It has the cytological map location 90C6. Protein features are: Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like; Glycosyltransferase subfamily 4-like, N-terminal domain. Its molecular function is described by: mannosyltransferase activity. It is involved in the biological process described with: protein glycosylation. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal; lethal - all die before end of pupal stage; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0264267	CR43767	-0.441202068	0.271771183	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR43767 (FBgn0264267). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2L:1158576..1159355. It has the cytological map location 21F1. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0032166	CG4619	-0.441063672	0.229463075	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4619 (FBgn0032166). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:9938863..9943058. It has the cytological map location 30F1. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 06-18 hour embryonic stages, during early larval stages.  "
FBgn0031494	CG17219	-0.441061837	0.266588719	0.999936032	METTL18	METTL18	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17219 (FBgn0031494). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:3029253..3030616. It has the cytological map location 23C4-23C5. Protein features are: Lysine methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase. Its molecular function is described by: S-adenosylmethionine-dependent methyltransferase activity. It is involved in the biological process described with: . 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages.  "
FBgn0032138	CG4364	-0.44095345	0.210917381	0.999936032	PES1	PES1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4364 (FBgn0032138). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:9708921..9711271. It has the cytological map location 30C5-30C6. Protein features are: BRCT domain; Pescadillo. Its molecular function is described by: RNA binding. It is involved in the biological process described with: maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). 2 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; embryonic/larval neuroblast; ganglion mother cell. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; some die during pupal stage; neuroanatomy defective; visible; viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0002522	lab	-0.440847009	0.258060774	0.999936032	NA	HOXA1;HOXB1;HOXD1	high;moderate;moderate	DNA-binding with transcription factor activity(Homeobox)	NA	NA	"The gene labial is referred to in FlyBase by the symbol Dmel\lab (CG1264, FBgn0002522). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:6661427..6678590. It has the cytological map location 84A1. Protein features are: Homeobox domain; Homeobox domain, metazoa; Homeobox domain-like; Homeobox, conserved site. Its molecular function is described by: transcription factor activity, sequence-specific DNA binding; transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; enhancer binding; protein heterodimerization activity; sequence-specific DNA binding. It is involved in the biological process described with: midgut development; cell fate determination; cell differentiation; brain development; positive regulation of decapentaplegic signaling pathway; positive regulation of transcription from RNA polymerase II promoter; brain segmentation; head morphogenesis. 38 alleles are reported. The phenotypes of these alleles manifest in: foregut; wing margin; frontal connective; antennal segment; adult gnathal segment; gland; compound cell cluster organ; segment of antenna; adult maxillary segment; embryonic/larval salivary gland; postgena; immaterial anatomical entity. The phenotypic classes of alleles include: lethal; phenotype; increased mortality during development; lethal - all die before end of P-stage; lethal - all die before end of pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages.  "
FBgn0038613	Vha100-4	-0.440784452	0.209198329	0.999936032	NA	ATP6V0A4;ATP6V0A1;ATP6V0A2;TCIRG1	moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene Vacuolar H<sup>+</sup> ATPase 100kD subunit 4 is referred to in FlyBase by the symbol Dmel\Vha100-4 (CG7678, FBgn0038613). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:18386841..18389805. It has the cytological map location 91A5. Protein features are: ATPase, V0 complex, subunit 116kDa, eukaryotic; V-type  ATPase, V0 complex, 116kDa subunit family. Its molecular function is described by: proton-transporting ATPase activity, rotational mechanism; ATPase binding. It is involved in the biological process described with: ATP hydrolysis coupled proton transport; ATP synthesis coupled proton transport; vacuolar proton-transporting V-type ATPase complex assembly; vacuolar acidification. 4 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval midgut. The phenotypic classes of alleles include: lethal - all die before end of larval stage; lethal - all die before end of second instar larval stage; increased mortality during development; phenotype; long lived; immune response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0035670	CG10472	-0.440375609	0.200634697	0.999936032	NA	CTRC;CTRB1;CTRB2	low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10472 (FBgn0035670). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:6061372..6062910. It has the cytological map location 65A5. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very low expression.  Peak expression observed during late larval stages.  "
FBgn0027562	CG10345	-0.440213379	0.294902322	0.999936032	NA	SCARB2;SCARB1	moderate;moderate	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG10345 (FBgn0027562). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:16597073..16604861. It has the cytological map location 89D5. Protein features are: CD36 family; CD36/scavenger receptor class B member 1. Its molecular function is unknown. The biological processes in which it is involved are not known. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: immune response defective; viable; short lived; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during early pupal stages.
FBgn0036563	CG13075	-0.440116428	0.262016015	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13075 (FBgn0036563). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:16083993..16085264. It has the cytological map location 72D1. Protein features are: Chitin binding domain. Its molecular function is described by: chitin binding. It is involved in the biological process described with: chitin metabolic process. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0030360	CG1806	-0.439672895	0.287786313	0.999936032	NA	SSPN	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1806 (FBgn0030360). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:12007176..12009904. It has the cytological map location 11A1. Protein features are: Sarcospan. Its molecular function is unknown. The biological processes in which it is involved are not known. 10 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 06-18 hour embryonic stages, during late pupal stages.  "
FBgn0034081	CG10731	-0.438610079	0.279057065	0.999936032	NA	ATP5S	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10731 (FBgn0034081). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:16148812..16149795. It has the cytological map location 52E11. Protein features are: ATP synthase subunit s, mitochondrial; Leucine-rich repeat domain, L domain-like. Its molecular function is described by: . It is involved in the biological process described with: proton transport. 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0064116	CG33713	-0.438298346	0.227527256	0.999936032	NA	ACBD6;LHX4-AS1;ACBD4;ACBD5;ACBD7;DBI	high;moderate;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG33713 (FBgn0064116). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:21317936..21319296. It has the cytological map location 19F4. Protein features are: Acyl-CoA-binding protein, ACBP; Ankyrin repeat; Ankyrin repeat-containing domain; FERM/acyl-CoA-binding protein, 3-helical bundle. Its molecular function is described by: fatty-acyl-CoA binding. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: feeding behavior defective; smell perception defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 06-12 hour embryonic stages, during early larval stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0064117	SLIRP1	-0.438298346	0.227527256	0.999936032	NA	SLIRP	moderate	NA	NA	NA	"The gene SRA stem-loop interacting RNA binding protein 1 is referred to in FlyBase by the symbol Dmel\SLIRP1 (CG33714, FBgn0064117). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:21317936..21319296. It has the cytological map location 19F4. Protein features are: RNA recognition motif domain; SLIRP, RNA recognition motif. Its molecular function is described by: nucleic acid binding; mRNA binding. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: smell perception defective; feeding behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 06-12 hour embryonic stages, during early larval stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0266172	pre-mod(mdg4)-E	-0.43821334	0.291274441	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\pre-mod(mdg4)-E (CG44878, FBgn0266172). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:21362968..21365488. It has the cytological map location 93D8. Its molecular function is described by: . It is involved in the biological process described with: . One allele is reported. No phenotypic data is available. No phenotypic class data is available."
FBgn0051864	Qtzl	-0.437604131	0.234800793	0.999936032	NA	NFS1;SCLY	moderate;high	NA	NA	NA	"The gene Quetzalcoatl is referred to in FlyBase by the symbol Dmel\Qtzl (CG31864, FBgn0051864).The gene has a gene model, but the supporting evidence is inconclusive. It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:11995740..11996723. It has the cytological map location 33B5. Protein features are: Aminotransferase class V domain; Cysteine desulfurase IscS; Pyridoxal phosphate-dependent transferase; Pyridoxal phosphate-dependent transferase, major region, subdomain 1. Its molecular function is described by: cysteine desulfurase activity; pyridoxal phosphate binding. It is involved in the biological process described with: [2Fe-2S] cluster assembly. One allele is reported. No phenotypic data is available. The phenotypic classes of allele include: sterile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during early pupal stages, in adult female stages.  "
FBgn0003515	st	-0.437432931	0.232155801	0.999936032	NA	ABCG5	moderate	NA	transmembrane protein	NA	"The gene scarlet is referred to in FlyBase by the symbol Dmel\st (CG4314, FBgn0003515). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:16497651..16500460. It has the cytological map location 73A3. Protein features are: AAA+ ATPase domain; ABC transporter, conserved site; ABC transporter-like; ABC-2 type transporter; P-loop containing nucleoside triphosphate hydrolase; Pigment precursor permease. Its molecular function is described by: synaptic vesicle amine transmembrane transporter activity; ATPase activity, coupled to transmembrane movement of substances; ATP binding. It is involved in the biological process described with: eye pigment precursor transport; ommochrome biosynthetic process; aminergic neurotransmitter loading into synaptic vesicle. 52 alleles are reported. The phenotype of these alleles manifest in: pigment cell. The phenotypic classes of alleles include: sterile; lethal; visible; eye color defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 06-18 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0032857	CG10947	-0.437422246	0.296653003	0.999936032	CAMKMT	CAMKMT	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10947 (FBgn0032857). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:20385293..20414800. It has the cytological map location 38C6. Protein features are: Lysine methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase. Its molecular function is described by: S-adenosylmethionine-dependent methyltransferase activity. It is involved in the biological process described with: regulation of translation. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the pupal period, in adult male stages.  "
FBgn0265937	CR44724	-0.43741944	0.268201422	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44724 (FBgn0265937). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2R:21297495..21298495. It has the cytological map location 57D8. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0005391	Yp2	-0.437115626	0.238685896	0.999936032	NA	PNLIPRP2;PNLIP;LIPH;PLA1A;PNLIPRP1;LIPI;PNLIPRP3;LIPG;LPL;LIPC	low;low;low;low;low;low;low;low;low;low	NA	NA	NA	"The gene Yolk protein 2 is referred to in FlyBase by the symbol Dmel\Yp2 (CG2979, FBgn0005391). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:10050951..10052636. It has the cytological map location 9A5. Protein features are: Alpha/Beta hydrolase fold; Lipase/vitellogenin; Triacylglycerol lipase family. Its molecular function is described by: carboxylic ester hydrolase activity. It is involved in the biological process described with: oogenesis; sex differentiation. 16 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; embryonic/larval neuroblast; mesothoracic tergum. The phenotypic classes of alleles include: neuroanatomy defective; some die during P-stage; increased mortality; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of extremely low expression.  Peak expression observed in adult female stages.  "
FBgn0031745	rau	-0.436711349	0.298727782	0.999936032	NA	NA	NA	NA	NA	NA	"The gene rau is referred to in FlyBase by the symbol Dmel\rau (CG8965, FBgn0031745). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:5859769..5879498. It has the cytological map location 26A1. Protein features are: Ras-associating (RA) domain; Ubiquitin-related domain. Its molecular function is described by: protein homodimerization activity; Ras GTPase binding. It is involved in the biological process described with: R7 cell development; positive regulation of fibroblast growth factor receptor signaling pathway; glial cell development; positive regulation of epidermal growth factor receptor signaling pathway. 17 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval optic stalk surface glial cell; fascicle; photoreceptor cell R7; eye. The phenotypic classes of alleles include: partially lethal; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 06-24 hour embryonic stages.  "
FBgn0015781	P5cr	-0.436632058	0.219605137	0.999936032	PYCR1	PYCR1;PYCRL;PYCR2	moderate;moderate;low	NA	NA	NA	"The gene Pyrroline 5-carboyxlate reductase is referred to in FlyBase by the symbol Dmel\P5cr (CG6009, FBgn0015781). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:19028931..19030159. It has the cytological map location 91E4. Protein features are: 6-phosphogluconate dehydrogenase C-terminal domain-like; NAD(P)-binding domain; Pyrroline-5-carboxylate reductase; Pyrroline-5-carboxylate reductase, catalytic, N-terminal; Pyrroline-5-carboxylate reductase, dimerisation domain. Its molecular function is described by: pyrroline-5-carboxylate reductase activity. It is involved in the biological process described with: oxidation-reduction process; proline biosynthetic process. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0004009	wg	-0.436513422	0.298430355	0.999936032	NA	WNT1;WNT4;WNT9A;WNT10B;WNT7A;WNT2;WNT11;WNT7B;WNT5A;WNT2B;WNT6;WNT10A;WNT5B;WNT3;WNT16;WNT3A;WNT9B	high;moderate;low;low;low;low;low;low;low;low;low;low;low;moderate;low;moderate;low	NA	NA	NA	NA
FBgn0050148	CG30148	-0.436441734	0.297981495	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG30148 (FBgn0050148). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:20546595..20547658. It has the cytological map location 57A5. Protein features are: Beta-1,3-glucan-binding protein, N-terminal. Its molecular function is described by: carbohydrate binding. The biological processes in which it is involved are not known. 4 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the larval period.  "
FBgn0001332	PRAS40	-0.436256472	0.221098809	0.999936032	NA	AKT1S1	low	NA	NA	NA	NA
FBgn0050456	CG30456	-0.436122129	0.223120396	0.999936032	NA	KALRN;ARHGEF25;TRIO;SLC26A10;ARHGEF40;PLEKHG4B;PLEKHG4	low;low;low;low;low;low;low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG30456 (FBgn0050456). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 2R:17100241..17107542. It has the cytological map location 53F8-53F9. Protein features are: Dbl homology (DH) domain; PH domain-like. Its molecular function is described by: Rho guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: imaginal disc-derived leg morphogenesis; positive regulation of Rho protein signal transduction. 10 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the pupal period.
FBgn0032943	Tsp39D	-0.435290163	0.237240734	0.999936032	NA	CD63	moderate	NA	transmembrane protein	NA	"The gene Tetraspanin 39D is referred to in FlyBase by the symbol Dmel\Tsp39D (CG8666, FBgn0032943). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:21344607..21358271. It has the cytological map location 39D1. Protein features are: Tetraspanin; Tetraspanin, EC2 domain; Tetraspanin/Peripherin. Its molecular function is described by: . It is involved in the biological process described with: cell surface receptor signaling pathway. 9 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed during late larval stages, at stages throughout the pupal period.  "
FBgn0039642	CG11882	-0.434651792	0.281871704	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG11882 (FBgn0039642). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:29147016..29148172. It has the cytological map location 98F12. Protein features are: Protein of unknown function DUF4506. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during early pupal stages.
FBgn0029975	spidey	-0.434306278	0.210620351	0.999936032	NA	HSD17B12;HSD17B3;HSDL1	high;moderate;low	NA	transmembrane protein	NA	"The gene spidey is referred to in FlyBase by the symbol Dmel\spidey (CG1444, FBgn0029975). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:7908931..7911885. It has the cytological map location 7C2. Protein features are: NAD(P)-binding domain; Short-chain dehydrogenase/reductase SDR. Its molecular function is unknown. It is involved in the biological process described with: cellular response to nutrient levels; negative regulation of cell growth; negative regulation of phosphatidylinositol 3-kinase signaling; negative regulation of DNA endoreduplication; positive regulation of lipid storage. 8 alleles are reported. The phenotypes of these alleles manifest in: leg; adult oenocyte; embryonic/larval oenocyte; lipid particle; nucleus; spiracle; head; embryonic/larval trachea; embryonic/larval tracheal system. The phenotypic classes of alleles include: stress response defective; increased mortality; some die during P-stage; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed in adult male stages.  "
FBgn0051637	CG31637	-0.434134625	0.235246915	0.999936032	NA	CHST6;CHST4;CHST1;CHST7;CHST5;CHST3;CHST2	high;moderate;moderate;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG31637 (FBgn0051637). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:6498647..6526996. It has the cytological map location 26D9-26E1. Protein features are: P-loop containing nucleoside triphosphate hydrolase; Sulfotransferase domain. Its molecular function is described by: N-acetylglucosamine 6-O-sulfotransferase activity. It is involved in the biological process described with: sulfur compound metabolic process. 10 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed during late pupal stages.
FBgn0037956	CG6959	-0.433591252	0.292100791	0.999936032	NA	TPBG;TPBGL	high;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6959 (FBgn0037956). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:11822702..11869460. It has the cytological map location 86F9-86F11. Protein features are: Cysteine-rich flanking region, C-terminal; Leucine-rich repeat; Leucine-rich repeat domain, L domain-like; Leucine-rich repeat, typical subtype. Its molecular function is unknown. It is involved in the biological process described with: axonogenesis. 14 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 06-18 hour embryonic stages, at stages throughout the pupal period.  "
FBgn0031344	CG7420	-0.433451928	0.269033001	0.999936032	SERGEF	SERGEF;RCC2	high;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7420 (FBgn0031344). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:1500784..1502904. It has the cytological map location 22A2. Protein features are: Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; Regulator of chromosome condensation, RCC1. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0004646	ogre	-0.433331916	0.258704392	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene optic ganglion reduced is referred to in FlyBase by the symbol Dmel\ogre (CG3039, FBgn0004646). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (1 unique). Gene sequence location is X:6973620..6991318. It has the cytological map location 6E4. Protein features are: Innexin. Its molecular function is described by: gap junction channel activity. It is involved in the biological process described with: visual behavior; phototransduction; intercellular transport. 20 alleles are reported. The phenotypes of these alleles manifest in: optic lobe; central nervous system; lamina monopolar neuron; photoreceptor cell. The phenotypic classes of alleles include: increased mortality; increased mortality during development; phenotype; lethal - all die before end of P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during early pupal stages.  "
FBgn0032549	CG4650	-0.433207437	0.198867546	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4650 (FBgn0032549). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:14773814..14774981. It has the cytological map location 35B5. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site. Its molecular function is unknown. It is involved in the biological process described with: proteolysis. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed during late larval stages, at stages throughout the pupal period.  "
FBgn0037900	CG5276	-0.433078867	0.23562426	0.999936032	CANT1	CANT1	high	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG5276 (FBgn0037900). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:11431738..11433543. It has the cytological map location 86E5. Protein features are: Apyrase. Its molecular function is described by: uridine-diphosphatase activity; nucleoside-triphosphatase activity; calcium ion binding; guanosine-diphosphatase activity; nucleoside-diphosphatase activity. It is involved in the biological process described with: proteoglycan biosynthetic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed in adult male stages.
FBgn0030272	CG15201	-0.432583501	0.298549601	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG15201 (FBgn0030272). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:11144120..11144809. It has the cytological map location 10A8. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed in adult male stages.
FBgn0011824	CG4038	-0.432510339	0.272619734	0.999936032	NA	GAR1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4038 (FBgn0011824). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:21095958..21097305. It has the cytological map location 57B20. Protein features are: H/ACA ribonucleoprotein complex, subunit Gar1; H/ACA ribonucleoprotein complex, subunit Gar1/Naf1; Translation protein, beta-barrel domain. Its molecular function is described by: box H/ACA snoRNA binding; snoRNA binding. It is involved in the biological process described with: rRNA pseudouridine synthesis; cellular response to starvation; snoRNA guided rRNA pseudouridine synthesis. 6 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; embryonic/larval neuroblast. The phenotypic classes of alleles include: partially lethal - majority die; neuroanatomy defective; some die during pupal stage; lethal - all die during larval stage; lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, during early larval stages.  "
FBgn0030997	CG7990	-0.431610682	0.272070748	0.999936032	NA	PGAP2;CWH43	moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7990 (FBgn0030997). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is X:19196058..19201979. It has the cytological map location 18A7-18B1. Protein features are: Frag1/DRAM/Sfk1. Its molecular function is described by: . It is involved in the biological process described with: . 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages.  "
FBgn0028482	bdl	-0.431493102	0.208036809	0.999936032	NA	IGSF9;IGSF9B	moderate;moderate	NA	transmembrane protein	NA	"The gene borderless is referred to in FlyBase by the symbol Dmel\bdl (CG16857, FBgn0028482). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:4324554..4331830. It has the cytological map location 24E1. Protein features are: Fibronectin type III; Immunoglobulin I-set; Immunoglobulin V-set domain; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold. Its molecular function is described by: protein binding involved in cell-cell adhesion. It is involved in the biological process described with: homophilic cell adhesion via plasma membrane adhesion molecules; axon ensheathment; glial cell growth; neuron cell-cell adhesion; R7 cell development. 17 alleles are reported. The phenotypes of these alleles manifest in: rhabdomere R7; embryonic/larval optic stalk; rhabdomere R8; axon; embryonic/larval wrapping glial cell of the eye disc. The phenotypic classes of alleles include: neuroanatomy defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed in adult male stages.  "
FBgn0039872	salt	-0.431493102	0.208036809	0.999936032	NA	SLC5A5;SLC5A8;SLC5A6;SLC5A12	moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene salty dog is referred to in FlyBase by the symbol Dmel\salt (CG2196, FBgn0039872). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:31751825..31754705. It has the cytological map location 100D2. Protein features are: Sodium/solute symporter. Its molecular function is described by: transporter activity. It is involved in the biological process described with: transmembrane transport. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; stress response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0010435	emp	-0.431426225	0.231489803	0.999936032	SCARB2	SCARB2;SCARB1	high;low	NA	transmembrane protein	NA	"The gene epithelial membrane protein is referred to in FlyBase by the symbol Dmel\emp (CG2727, FBgn0010435). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is 2R:24976456..24986070. It has the cytological map location 60E11. Protein features are: CD36 family; CD36/scavenger receptor class B member 1; Lysosome membrane protein II. Its molecular function is described by: receptor activity. It is involved in the biological process described with: autophagic cell death; salivary gland cell autophagic cell death. 12 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0024315	Picot	-0.431285927	0.211921734	0.999936032	NA	SLC17A5;SLC17A4;SLC17A3;SLC17A2;SLC17A1;SLC17A6;SLC17A8;SLC17A7	moderate;high;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene Picot is referred to in FlyBase by the symbol Dmel\Picot (CG8098, FBgn0024315). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 2R:16655323..16667675. It has the cytological map location 53C15-53D1. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain; Na-dependent inorganic phosphate cotransporter. Its molecular function is described by: phosphate ion transmembrane transporter activity; transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; phosphate ion transmembrane transport; anion transport. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during early larval stages.  "
FBgn0038250	CG3505	-0.430930938	0.247570646	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3505 (FBgn0038250). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:14657447..14659228. It has the cytological map location 88C10. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Proteinase, regulatory CLIP domain; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site. Its molecular function is unknown. It is involved in the biological process described with: sleep; proteolysis. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed at stages throughout the pupal period.  "
FBgn0039050	CG17110	-0.430930938	0.247570646	0.999936032	ACY1	ACY1;ABHD14A-ACY1;PM20D1;ABHD14A	moderate;moderate;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17110 (FBgn0039050). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:23091724..23095441. It has the cytological map location 94D13. Protein features are: N-acyl-L-amino-acid amidohydrolase; Peptidase M20; Peptidase M20, dimerisation domain. Its molecular function is described by: aminoacylase activity. It is involved in the biological process described with: cellular amino acid metabolic process. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed in adult male stages.  "
FBgn0028694	Rpn11	-0.430914194	0.219320851	0.999936032	PSMD14	PSMD14	high	NA	NA	NA	"The gene Regulatory particle non-ATPase 11 is referred to in FlyBase by the symbol Dmel\Rpn11 (CG18174, FBgn0028694). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:5058404..5059790. It has the cytological map location 25C3. Protein features are: 26S Proteasome non-ATPase regulatory subunit 14; JAB1/MPN/MOV34 metalloenzyme domain; Rpn11/EIF3F, C-terminal. Its molecular function is described by: Lys63-specific deubiquitinase activity; thiol-dependent ubiquitin-specific protease activity. It is involved in the biological process described with: protein deubiquitination; proteasome-mediated ubiquitin-dependent protein catabolic process. 13 alleles are reported. The phenotypes of these alleles manifest in: wing margin bristle; eye; wing; rhabdomere. The phenotypic classes of alleles include: lethal; increased mortality; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.  "
FBgn0085428	Nox	-0.430805938	0.305179709	0.999936032	NA	NOX5;NOX1	high;moderate	NA	transmembrane protein	NA	"The gene NADPH oxidase is referred to in FlyBase by the symbol Dmel\Nox (CG34399, FBgn0085428). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 2R:16307269..16316485. It has the cytological map location 53B2-53B3. Protein features are: EF-Hand 1, calcium-binding site; EF-hand domain; EF-hand domain pair; FAD-binding 8; Ferredoxin reductase-type FAD-binding domain; Ferric reductase transmembrane component-like domain; Ferric reductase, NAD binding domain; NADPH oxidase 5; Riboflavin synthase-like beta-barrel. Its molecular function is described by: calcium ion binding; superoxide-generating NADPH oxidase activity. It is involved in the biological process described with: positive regulation of smooth muscle contraction; ovulation; oxidation-reduction process; superoxide anion generation; positive regulation of calcium-mediated signaling. 13 alleles are reported. The phenotypes of these alleles manifest in: wing; ovary; clypeus; trichogen cell; adult head. The phenotypic classes of alleles include: visible; viable; female sterile; stress response defective; semi-sterile; size defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-18 embryonic stages, during late pupal stages.  "
FBgn0033519	CG11825	-0.430714961	0.279427689	0.999936032	NA	HIGD1C;HIGD1A;HIGD1B;HIGD2A	high;high;moderate;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11825 (FBgn0033519). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 2R:10420414..10423650. It has the cytological map location 47A7. Protein features are: Hypoxia induced protein, domain. Its molecular function is unknown. It is involved in the biological process described with: copper ion homeostasis. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0263598	Vha68-2	-0.430658188	0.210084234	0.999936032	NA	ATP6V1A	high	NA	NA	NA	"The gene Vacuolar H<sup>+</sup> ATPase 68 kDa subunit 2 is referred to in FlyBase by the symbol Dmel\Vha68-2 (CG3762, FBgn0263598). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (1 unique). Gene sequence location is 2L:12974322..12978607. It has the cytological map location 34A3. Protein features are: ATPase, F1/V1 complex, beta/alpha subunit, C-terminal; ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain; ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain; ATPase, V1 complex, subunit A; ATPase, alpha/beta subunit, nucleotide-binding domain, active site; ATPsynthase alpha/beta subunit, N-terminal extension; P-loop containing nucleoside triphosphate hydrolase; V-type ATP synthase catalytic alpha chain. Its molecular function is described by: proton-transporting ATPase activity, rotational mechanism; ATP binding. It is involved in the biological process described with: lumen formation, open tracheal system; endosomal lumen acidification; ATP metabolic process; ATP hydrolysis coupled proton transport; imaginal disc growth; endosomal transport. 22 alleles are reported. The phenotypes of these alleles manifest in: follicle cell; multivesicular body; mesothoracic tergum; eye disc; terminal tracheal cell; Malpighian tubule; endosome; embryonic/larval Malpighian tubule. The phenotypic classes of alleles include: increased mortality during development; phenotype; increased mortality; some die during larval stage; lethal - all die before end of P-stage."
FBgn0037976	Tk	-0.430652519	0.227070894	0.999936032	NA	TAC1	low	NA	NA	NA	"The gene Tachykinin is referred to in FlyBase by the symbol Dmel\Tk (CG14734, FBgn0037976). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:11994175..12005473. It has the cytological map location 87A4. Its molecular function is described by: receptor binding; tachykinin receptor binding; neuropeptide hormone activity. It is involved in the biological process described with: tachykinin receptor signaling pathway; lipid metabolic process; adult walking behavior; sensory perception of smell; response to pheromone; positive regulation of sensory perception of pain; neuropeptide signaling pathway; inter-male aggressive behavior. 17 alleles are reported. The phenotype of these alleles manifest in: enterocyte. The phenotypic classes of alleles include: mating defective; phenotype; behavior defective; mating behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, in adult male stages.  "
FBgn0035083	Tina-1	-0.430548239	0.212082209	0.999936032	NA	GGACT	moderate	NA	NA	NA	"The gene Troponin C-akin-1 is referred to in FlyBase by the symbol Dmel\Tina-1 (CG2803, FBgn0035083). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:24940625..24942413. It has the cytological map location 60E5-60E8. Protein features are: Gamma-glutamyl cyclotransferase-like; Gamma-glutamylcyclotransferase, AIG2-like. Its molecular function is described by: structural constituent of muscle. It is involved in the biological process described with: heart development. 9 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0039471	CG6295	-0.430429609	0.209896883	0.999936032	NA	LIPI	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6295 (FBgn0039471). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:27005899..27007055. It has the cytological map location 97D13. Protein features are: Alpha/Beta hydrolase fold; Lipase, N-terminal; Lipase/vitellogenin; Triacylglycerol lipase family; Vespid venom allergen phospholipase A1. Its molecular function is described by: lipase activity; phosphatidylcholine 1-acylhydrolase activity. It is involved in the biological process described with: lipid catabolic process. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; flight defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0035753	RpL18	-0.429773285	0.212470939	0.999936032	RPL18	RPL18	high	NA	NA	NA	"The gene Ribosomal protein L18 is referred to in FlyBase by the symbol Dmel\RpL18 (CG8615, FBgn0035753). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3L:7240203..7241351. It has the cytological map location 65E9. Protein features are: Ribosomal protein L18e; Ribosomal protein L18e, conserved site; Ribosomal protein L18e/L15P. Its molecular function is described by: structural constituent of ribosome; RNA binding. It is involved in the biological process described with: cytoplasmic translation; translation. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die during larval stage; lethal; lethal - all die during pupal stage; some die during pupal stage; lethal - all die before end of pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, in adult female stages.  "
FBgn0051446	CG31446	-0.429717413	0.215052215	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG31446 (FBgn0051446). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:15693086..15694194. It has the cytological map location 89A2. Protein features are: Calycin. Its molecular function is described by: . It is involved in the biological process described with: . 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages.
FBgn0051116	ClC-a	-0.429675185	0.269708969	0.999936032	NA	CLCN2;CLCN1;CLCNKB;CLCNKA	high;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene Chloride channel-a is referred to in FlyBase by the symbol Dmel\ClC-a (CG31116, FBgn0051116). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (all unique). Gene sequence location is 3R:11797244..11813207. It has the cytological map location 86F8. Protein features are: CBS domain; Chloride channel, core; Chloride channel, voltage gated. Its molecular function is described by: chloride channel activity; voltage-gated chloride channel activity. It is involved in the biological process described with: chloride transmembrane transport; chloride transport; renal water transport; transepithelial water transport; renal water homeostasis; transepithelial chloride transport. 10 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages.  "
FBgn0024995	CG2680	-0.429592037	0.304066166	0.999936032	NA	PDXP;PGP;LHPP	moderate;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG2680 (FBgn0024995). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:2706151..2707427. It has the cytological map location 3B2. Protein features are: HAD-like domain; HAD-superfamily hydrolase, subfamily IIA. Its molecular function is described by: phosphoprotein phosphatase activity; phosphatase activity. It is involved in the biological process described with: protein dephosphorylation. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during early larval stages, in stages of adults of both sexes.  "
FBgn0051823	CG31823	-0.429104485	0.276870948	0.999936032	NA	SCPEP1;CPVL;CTSA	moderate;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31823 (FBgn0051823). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:15898879..15900524. It has the cytological map location 35D6. Protein features are: Alpha/Beta hydrolase fold; Peptidase S10, serine carboxypeptidase; Serine carboxypeptidase, serine active site. Its molecular function is described by: serine-type carboxypeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: short lived; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, in adult male stages.  "
FBgn0038903	RpI12	-0.428734101	0.276141715	0.999936032	ZNRD1	ZNRD1	high	NA	NA	NA	"The gene RpI12 is referred to in FlyBase by the symbol Dmel\RpI12 (CG13418, FBgn0038903). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:21777203..21777847. It has the cytological map location 93F9. Protein features are: DNA-directed RNA polymerase M, 15kDa subunit, conserved site; DNA-directed RNA polymerase subunit/transcription factor S; Pol I subunit A12, C-terminal zinc ribbon; Zinc finger, TFIIS-type. Its molecular function is described by: RNA polymerase I activity; nucleic acid binding; zinc ion binding. It is involved in the biological process described with: mRNA cleavage; termination of RNA polymerase I transcription. 3 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: some die during pupal stage; partially lethal - majority die; visible; lethal - all die during P-stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed during early larval stages.  "
FBgn0263916	Ent2	-0.428669308	0.220721378	0.999936032	NA	SLC29A1;SLC29A3;SLC29A2	moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene Equilibrative nucleoside transporter 2 is referred to in FlyBase by the symbol Dmel\Ent2 (CG31911, FBgn0263916). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:6562325..6564709. It has the cytological map location 26E3. Protein features are: Equilibrative nucleoside transporter; Major facilitator superfamily domain. Its molecular function is described by: nucleoside transmembrane transporter activity. It is involved in the biological process described with: negative regulation of calcium ion import; nucleoside transport; associative learning; nucleoside transmembrane transport; chemical synaptic transmission. 13 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval neuromuscular junction; wing; motor neuron; synapse. The phenotypic classes of alleles include: phenotype; increased mortality during development; increased mortality; lethal."
FBgn0050159	CG30159	-0.428505963	0.233136492	0.999936032	NA	C3orf33	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG30159 (FBgn0050159). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:6992681..6994306. It has the cytological map location 42E4. Its molecular function is unknown. It is involved in the biological process described with: regulation of MAPK cascade. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages.
FBgn0039306	RIOK2	-0.428348369	0.256592188	0.999936032	NA	RIOK2	high	NA	NA	NA	"The gene RIO kinase 2 is referred to in FlyBase by the symbol Dmel\RIOK2 (CG11859, FBgn0039306). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:25265844..25267757. It has the cytological map location 96C8. Protein features are: Protein kinase-like domain; RIO kinase; RIO kinase, conserved site; RIO2 kinase winged helix domain, N-terminal; Serine/threonine-protein kinase Rio2; Winged helix-turn-helix DNA-binding domain. Its molecular function is described by: ATP binding; protein kinase activity; protein serine/threonine kinase activity. It is involved in the biological process described with: positive regulation of peptide hormone secretion; cellular response to starvation; positive regulation of glial cell proliferation; protein phosphorylation; positive regulation of multicellular organism growth. 6 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum; embryonic/larval neuroblast; ganglion mother cell. The phenotypic classes of alleles include: visible; phenotype; increased mortality during development; lethal - all die before end of P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0050160	CG30160	-0.427850931	0.214732721	0.999936032	NA	CD63	moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG30160 (FBgn0050160). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:7005157..7006136. It has the cytological map location 42E4-42E5. Protein features are: Tetraspanin; Tetraspanin, EC2 domain; Tetraspanin/Peripherin. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, during late larval stages, in adult male stages.  "
FBgn0036254	CG5645	-0.427796097	0.281128413	0.999936032	KRI1	KRI1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5645 (FBgn0036254). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:12133771..12136706. It has the cytological map location 68F5. Protein features are: KRR1 interacting protein 1; Kri1-like, C-terminal. Its molecular function is unknown. It is involved in the biological process described with: endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). 4 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: lethal; lethal - all die during larval stage; visible; viable; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0036364	CG14109	-0.427674633	0.308754668	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14109 (FBgn0036364). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:13440910..13442420. It has the cytological map location 70B1. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during late larval stages, at stages throughout the pupal period.  "
FBgn0014018	Rel	-0.42762127	0.241087752	0.999936032	NA	NFKB1;NFKB2;RELB;RELA;REL	high;moderate;low;low;low	DNA-binding with transcription factor activity(RHD|TIG)	NA	NA	"The gene Relish is referred to in FlyBase by the symbol Dmel\Rel (CG11992, FBgn0014018). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3R:9044183..9047977. It has the cytological map location 85C3. Protein features are: Ankyrin repeat; Ankyrin repeat-containing domain; IPT domain; Immunoglobulin E-set; Immunoglobulin-like fold; NF-kappa-B/Dorsal; NFkappaB IPT domain; Rel homology dimerisation domain; Rel homology domain (RHD), DNA-binding domain; p53-like transcription factor, DNA-binding. Its molecular function is described by: transcription factor activity, sequence-specific DNA binding; DNA binding; protein binding; chromatin binding; sequence-specific DNA binding; RNA polymerase II regulatory region sequence-specific DNA binding; RNA polymerase II transcription factor activity, sequence-specific DNA binding; transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding. It is involved in the biological process described with 26 unique terms, many of which group under: cellular component morphogenesis; nitric oxide metabolic process; response to extracellular stimulus; positive regulation of defense response to virus by host; cellular response to DNA damage stimulus; positive regulation of nitric oxide metabolic process; response to chemical; positive regulation of transcription, DNA-templated; response to organic substance; negative regulation of nucleic acid-templated transcription; positive regulation of innate immune response; cellular response to amino acid starvation. 65 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; dorsocentral bristle; wing; adult brain; dorsal multidendritic neuron ddaC; macrochaeta; intestinal stem cell; adult posterior midgut epithelium; abdominal anterior ventral multidendritic neuron vdaa; lamina. The phenotypic classes of alleles include: cell death defective; neuroanatomy defective; pain response defective; some die during P-stage; fertile; increased mortality; visible; viable; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed during early pupal stages.  "
FBgn0038420	CG10311	-0.427264342	0.263397119	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG10311 (FBgn0038420). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:16350786..16357015. It has the cytological map location 89B13. Protein features are: Protein of unknown function DUF4728. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages.
FBgn0030102	SmydA-9	-0.427194996	0.27866549	0.999936032	NA	SMYD2;SMYD1;SMYD3	moderate;low;low	NA	NA	NA	"The gene SET and MYND domain containing, arthropod-specific, member 9 is referred to in FlyBase by the symbol Dmel\SmydA-9 (CG12119, FBgn0030102). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:9206126..9210887. It has the cytological map location 8D1. Protein features are: SET domain. Its molecular function is described by: histone deacetylase binding. It is involved in the biological process described with: negative regulation of gene expression. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed during early pupal stages.  "
FBgn0086906	sls	-0.426930352	0.238511199	0.999936032	NA	HMCN1;OBSCN;OBSL1;TTN;SPEG	high;high;moderate;low;low	NA	NA	NA	"The gene sallimus is referred to in FlyBase by the symbol Dmel\sls (CG1915, FBgn0086906). It is a protein_coding_gene from Drosophila melanogaster. It has 13 annotated transcripts and 13 polypeptides (all unique). Gene sequence location is 3L:2039681..2115611. It has the cytological map location 62C2-62C4. Protein features are: Fibronectin type III; Immunoglobulin I-set; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold; Invertebrate Titin, immunoglobulin (Ig) repeats; SH3 domain; Titin, invertebrate. Its molecular function is described by: structural constituent of muscle; actin binding; protein binding. It is involved in the biological process described with 12 unique terms, many of which group under: nuclear chromosome segregation; sister chromatid segregation; muscle organ development; cytoskeleton organization; mesoderm development; single-multicellular organism process; regulation of cellular process; locomotion; somatic muscle development; cell cycle. 75 alleles are reported. The phenotypes of these alleles manifest in: adult mesothoracic segment; Z disc; embryonic segment; muscle tendon junction; midgut primordium; single-organism process; myosin II complex; embryonic/larval digestive system; eo-type sensillum; organ system subdivision. The phenotypic classes of alleles include: phenotype; increased mortality; stress response defective; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.  "
FBgn0052473	CG32473	-0.426854109	0.218491007	0.999936032	NA	ENPEP;ANPEP;TRHDE;LVRN;LNPEP;ERAP1;ERAP2;NPEPPS	moderate;moderate;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32473 (FBgn0052473). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3R:13302648..13312785. It has the cytological map location 87E5. Protein features are: Aminopeptidase A; Aminopeptidase N-type; ERAP1-like C-terminal domain; Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase; Peptidase M1, membrane alanine aminopeptidase, N-terminal. Its molecular function is described by: zinc ion binding; metalloaminopeptidase activity; peptide binding. It is involved in the biological process described with: proteolysis; peptide catabolic process; angiotensin maturation. 16 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in adult female stages.  "
FBgn0039407	CG14544	-0.426710716	0.30332859	0.999936032	TRMT61A	TRMT61A	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG14544 (FBgn0039407). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:26059496..26061293. It has the cytological map location 96F10. Protein features are: S-adenosyl-L-methionine-dependent methyltransferase; tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14. Its molecular function is described by: tRNA (adenine-N1-)-methyltransferase activity. It is involved in the biological process described with: lateral inhibition; tRNA methylation. 3 alleles are reported. The phenotypes of these alleles manifest in: chaeta; trichogen cell; embryonic/larval brain. The phenotypic classes of alleles include: lethal; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-12 hour embryonic stages.
FBgn0030000	CG2260	-0.426210878	0.256380734	0.999936032	WDR46	WDR46;MIR6873	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG2260 (FBgn0030000). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:8119082..8121147. It has the cytological map location 7D6. Protein features are: BING4, C-terminal domain; WD40 repeat; WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. It is involved in the biological process described with: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). 3 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval somatic muscle; trichogen cell; mesothoracic tergum; ganglion mother cell. The phenotypic classes of alleles include: lethal; visible; viable; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0261015	Pif1A	-0.425910879	0.238031728	0.999936032	NA	CCDC157	low	DNA-binding with transcription factor activity	NA	NA	"The gene PFTAIRE-interacting factor 1A is referred to in FlyBase by the symbol Dmel\Pif1A (CG42599, FBgn0261015). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 3R:8774286..8801176. It has the cytological map location 85B1. Protein features are: Coiled-coil domain-containing protein 157; Janus kinase and microtubule-interacting protein, C-terminal domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 15 alleles are reported. The phenotype of these alleles manifest in: spermatid. The phenotypic classes of alleles include: male sterile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late pupal stages, in adult male stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0010501	Dcp-1	-0.425366522	0.230351087	0.999936032	NA	CASP7;CASP6;CASP3;CASP9;CFLAR;CASP2;CASP8;CASP10	high;moderate;moderate;low;moderate;low;low;low	NA	NA	NA	"The gene Death caspase-1 is referred to in FlyBase by the symbol Dmel\Dcp-1 (CG5370, FBgn0010501). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:23551313..23553547. It has the cytological map location 59E3. Protein features are: Caspase-like domain; Peptidase C14,  p20 domain; Peptidase C14, caspase non-catalytic subunit p10; Peptidase C14A, caspase catalytic domain; Peptidase family C14A, His active site; Peptidase family C14A, cysteine active site. Its molecular function is described by: cysteine-type endopeptidase activity involved in execution phase of apoptosis; cysteine-type endopeptidase activity; protein binding; BIR domain binding. It is involved in the biological process described with 18 unique terms, many of which group under: regulation of metabolic process; synaptic signaling; nitrogen compound metabolic process; cellular response to stress; cytoskeleton organization; cell communication; instar larval or pupal morphogenesis; organonitrogen compound metabolic process; macroautophagy; response to starvation; generation of neurons. 38 alleles are reported. The phenotypes of these alleles manifest in: compound sense organ; female germline cyst; cell part; female reproductive system; male germline cell; larva; chaeta; procephalic segment; testis; cell projection. The phenotypic classes of alleles include: sterile; decreased cell death; cell death defective; neuroanatomy defective; viable; phenotype; neurophysiology defective; stress response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0003638	su(w[a])	-0.424634905	0.240961273	0.999936032	NA	SFSWAP	high	NA	NA	NA	"The gene suppressor of white-apricot is referred to in FlyBase by the symbol Dmel\su(w<sup>a</sup>) (CG3019, FBgn0003638). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (6 unique). Gene sequence location is X:1012779..1046040. It has the cytological map location 1E1. Protein features are: SWAP/Surp; Suppressor of white apricot N-terminal domain. Its molecular function is described by: RNA binding. It is involved in the biological process described with: mRNA 5'-splice site recognition. 58 alleles are reported. The phenotypes of these alleles manifest in: Z disc; pigment cell; mesothoracic tergum; sarcomere; myofibril. The phenotypic classes of alleles include: viable; visible; flightless; wild-type. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed during early pupal stages.  "
FBgn0030348	CG10352	-0.423995226	0.300907845	0.999936032	NA	PGP;PDXP	moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10352 (FBgn0030348). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:11875306..11877168. It has the cytological map location 10F2. Protein features are: HAD-like domain; HAD-superfamily hydrolase, subfamily IIA. Its molecular function is described by: phosphatase activity; phosphoprotein phosphatase activity. It is involved in the biological process described with: dephosphorylation; protein dephosphorylation. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0036620	CG4842	-0.423995226	0.300907845	0.999936032	NA	HPGD	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4842 (FBgn0036620). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:16368389..16369518. It has the cytological map location 72E2-72E3. Protein features are: Alcohol dehydrogenase, Ceratitis-type; Alcohol dehydrogenase, insect-type; NAD(P)-binding domain; Short-chain dehydrogenase/reductase SDR; Short-chain dehydrogenase/reductase, conserved site. Its molecular function is described by: alcohol dehydrogenase (NAD) activity. It is involved in the biological process described with: neuron projection morphogenesis; oxidation-reduction process. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: short lived; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during late pupal stages.  "
FBgn0027547	CG1927	-0.423802441	0.219173777	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG1927 (FBgn0027547). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:1966725..1970079. It has the cytological map location 62B12. Its molecular function is unknown. The biological processes in which it is involved are not known. 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 18-24 hour embryonic stages.
FBgn0052412	QC	-0.423028118	0.288970909	0.999936032	NA	QPCT;QPCTL	moderate;moderate	NA	NA	NA	"The gene Glutaminyl cyclase is referred to in FlyBase by the symbol Dmel\QC (CG32412, FBgn0052412). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:5900835..5902456. It has the cytological map location 64F4-64F5. Protein features are: Peptidase M28. Its molecular function is described by: glutaminyl-peptide cyclotransferase activity. It is involved in the biological process described with: peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase. 7 alleles are reported. The phenotype of these alleles manifest in: chaeta. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, in adult female stages.  "
FBgn0005771	noc	-0.422675208	0.25829765	0.999936032	NA	ZNF503;ZNF703	high;moderate	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene no ocelli is referred to in FlyBase by the symbol Dmel\noc (CG4491, FBgn0005771). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:14490859..14494019. It has the cytological map location 35B2. Protein features are: Zinc finger C2H2-type. Its molecular function is described by: nucleic acid binding; protein binding. It is involved in the biological process described with 12 unique terms, many of which group under: regulation of cellular biosynthetic process; head development; multi-organism behavior; leg disc development; ocellus development; eye development; aggressive behavior; cell proliferation; regulation of cellular metabolic process; central nervous system development. 47 alleles are reported. The phenotypes of these alleles manifest in: nervous system; multi-tissue structure; adult thoracic sensillum; wing; postalar bristle; adult external mesothorax; ganglionic branch primordium; lateral trunk anterior branch; appendage; supraesophageal ganglion. The phenotypic classes of alleles include: some die during larval stage; behavior defective; lethal; lethal - all die before end of larval stage; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages.  "
FBgn0033918	CG8531	-0.42200982	0.236573605	0.999936032	DNAJC11	DNAJC11	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8531 (FBgn0033918). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:14256493..14258787. It has the cytological map location 50E6. Protein features are: DnaJ domain; DnaJ-like protein C11, C-terminal. Its molecular function is described by: ATPase activator activity. It is involved in the biological process described with: protein import into mitochondrial matrix. 4 alleles are reported. The phenotype of these alleles manifest in: wing blade posterior compartment. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.  "
FBgn0033321	CG8738	-0.421889519	0.308242003	0.999936032	NA	KLK3;KLK1;KLKB1;F11;KLK2;KLK11	low;low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8738 (FBgn0033321). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:8696428..8698583. It has the cytological map location 44E2. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain. Its molecular function is unknown. It is involved in the biological process described with: proteolysis. 4 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the pupal period.  "
FBgn0035154	CG3344	-0.421695022	0.219306426	0.999936032	SCPEP1	SCPEP1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3344 (FBgn0035154). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:685942..687958. It has the cytological map location 61C8. Protein features are: Alpha/Beta hydrolase fold; Peptidase S10, serine carboxypeptidase. Its molecular function is described by: serine-type carboxypeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: paralytic; viable; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late larval stages.  "
FBgn0051140	CG31140	-0.421617743	0.31263422	0.999936032	NA	DGKQ	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31140 (FBgn0051140). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (all unique). Gene sequence location is 3R:23963180..23983232. It has the cytological map location 95D1-95D4. Protein features are: Diacylglycerol kinase, accessory domain; Diacylglycerol kinase, catalytic domain; Diacylglycerol/phorbol-ester binding; Inorganic polyphosphate/ATP-NAD kinase, domain 1; NAD kinase/diacylglycerol kinase-like domain; Protein kinase C-like, phorbol ester/diacylglycerol-binding domain; RNA recognition motif domain; Ras-associating (RA) domain; Ubiquitin-related domain. Its molecular function is described by: NAD+ kinase activity; diacylglycerol kinase activity; nucleic acid binding. It is involved in the biological process described with: G-protein coupled receptor signaling pathway; phosphorylation; protein kinase C signaling; protein kinase C-activating G-protein coupled receptor signaling pathway; lateral inhibition; metabolic process. 10 alleles are reported. The phenotypes of these alleles manifest in: chaeta; abdominal dorsal multidendritic neuron ddaE; dendritic tree; abdominal dorsal multidendritic neuron ddaD; myofibril. The phenotypic classes of alleles include: increased mortality; visible; phenotype; increased mortality during development; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages.  "
FBgn0030432	CG4404	-0.421338847	0.251722489	0.999936032	NA	NA	NA	DNA-binding with transcription factor activity(BESS)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4404 (FBgn0030432). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:12903745..12906018. It has the cytological map location 11D1. Protein features are: BESS motif; MADF domain. Its molecular function is described by: DNA binding. The biological processes in which it is involved are not known. 8 alleles are reported. The phenotypes of these alleles manifest in: chaeta; wing; trichogen cell; Z disc; sarcomere. The phenotypic classes of alleles include: partially lethal - majority die; viable; visible; lethal - all die during larval stage; flightless; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0034179	CG6805	-0.421314107	0.297947389	0.999936032	NA	INPP5K;INPP5J	high;high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6805 (FBgn0034179). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:17005451..17007501. It has the cytological map location 53E4. Protein features are: Endonuclease/exonuclease/phosphatase; Inositol polyphosphate-related phosphatase. Its molecular function is described by: inositol trisphosphate phosphatase activity. It is involved in the biological process described with: dephosphorylation; phosphatidylinositol dephosphorylation. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; flight defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.  "
FBgn0050481	mRpL53	-0.421039889	0.250392864	0.999936032	NA	MRPL53	high	NA	NA	NA	"The gene mitochondrial ribosomal protein L53 is referred to in FlyBase by the symbol Dmel\mRpL53 (CG30481, FBgn0050481). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:13954195..13955664. It has the cytological map location 50C16. Protein features are: Ribosomal protein L53, mitochondrial. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: larval lymph gland hemopoiesis; mitochondrial translation. 3 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval lymph gland. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in stages of adults of both sexes.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0039757	RpS7	-0.420903571	0.219717864	0.999936032	RPS7	RPS7	high	NA	NA	NA	"The gene Ribosomal protein S7 is referred to in FlyBase by the symbol Dmel\RpS7 (CG1883, FBgn0039757). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 3R:30206447..30209020. It has the cytological map location 99E2. Protein features are: Ribosomal protein S7e. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: translation; ribosomal small subunit biogenesis; rRNA processing; cytoplasmic translation. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; lethal - all die during larval stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages.  "
FBgn0086365	Orct2	-0.420781345	0.27808909	0.999936032	NA	SLC22A4;SLC22A5;SLC22A13;SLC22A16	moderate;high;low;low	NA	transmembrane protein	NA	"The gene Organic cation transporter 2 is referred to in FlyBase by the symbol Dmel\Orct2 (CG13610, FBgn0086365). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:24273029..24275728. It has the cytological map location 95F8. Protein features are: Major facilitator superfamily domain; Major facilitator,  sugar transporter-like. Its molecular function is described by: organic cation transmembrane transporter activity; organic anion transmembrane transporter activity. It is involved in the biological process described with: positive regulation of cell growth; transmembrane transport; organic cation transport; germ-band shortening; positive regulation of multicellular organism growth. 15 alleles are reported. The phenotypes of these alleles manifest in: germ band; eye; wing margin bristle; wing. The phenotypic classes of alleles include: increased mortality; viable; phenotype; body size defective; cell size defective; some die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0028468	rtet	-0.420765726	0.240432207	0.999936032	NA	MFSD10	high	NA	transmembrane protein	NA	"The gene tetracycline resistance is referred to in FlyBase by the symbol Dmel\rtet (CG5760, FBgn0028468). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:21108446..21110834. It has the cytological map location 93B12. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain; Sugar transporter, conserved site. Its molecular function is described by: tetracycline transporter activity. It is involved in the biological process described with: oogenesis; transmembrane transport; tetracycline transport. 10 alleles are reported. The phenotypes of these alleles manifest in: ovariole; egg. The phenotypic classes of alleles include: viable; fertile; lethal - all die before end of larval stage; female sterile; lethal; some die during larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 12-18 hour embryonic stages, during late pupal stages.  "
FBgn0037955	CG6950	-0.420521068	0.233788467	0.999936032	CCBL2	KYAT3;KYAT1	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6950 (FBgn0037955). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 3R:11820381..11822493. It has the cytological map location 86F9. Protein features are: Aminotransferase, class I/classII; Kynurenine--oxoglutarate transaminase 3; Pyridoxal phosphate-dependent transferase; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; Pyridoxal phosphate-dependent transferase, subdomain 2. Its molecular function is described by: pyridoxal phosphate binding; kynurenine aminotransferase activity. It is involved in the biological process described with: kynurenine metabolic process; biosynthetic process. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: flightless; fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed during early larval stages, in adult female stages.  "
FBgn0050047	CG30047	-0.420060835	0.235365197	0.999936032	ERMP1	ERMP1	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG30047 (FBgn0050047). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:12351793..12355413. It has the cytological map location 49A1. Protein features are: Peptidase M28. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0037678	CG16749	-0.419981683	0.220525074	0.999936032	NA	KLK3;KLK10;KLK5;KLK1;KLK6	high;high;high;high;high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG16749 (FBgn0037678). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:9330885..9331885. It has the cytological map location 85D11. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed at stages throughout the larval period.  "
FBgn0038271	UQCR-C1	-0.419664189	0.221551894	0.999936032	NA	PMPCB;UQCRC1	high;moderate	NA	NA	NA	"The gene Ubiquinol-cytochrome c reductase core protein 1 is referred to in FlyBase by the symbol Dmel\UQCR-C1 (CG3731, FBgn0038271). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:14890231..14892387. It has the cytological map location 88D6. Protein features are: Metalloenzyme, LuxS/M16 peptidase-like; Peptidase M16, C-terminal; Peptidase M16, N-terminal; Peptidase M16, zinc-binding site. Its molecular function is described by: zinc ion binding; metalloendopeptidase activity; ubiquinol-cytochrome-c reductase activity. It is involved in the biological process described with: mitochondrial electron transport, ubiquinol to cytochrome c; aerobic respiration; protein processing. 6 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: viable; visible; lethal - all die during larval stage; fertile; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0035325	CG13806	-0.419114662	0.242933182	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG13806 (FBgn0035325). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:2266394..2267640. It has the cytological map location 62D4. Protein features are: Chitin binding domain. Its molecular function is described by: chitin binding. It is involved in the biological process described with: chitin metabolic process. 5 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages.
FBgn0040346	CG3704	-0.418627129	0.24377228	0.999936032	NA	GPN1;ZNF512	high;moderate	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG3704 (FBgn0040346). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:939170..940805. It has the cytological map location 1D2. Protein features are: GPN-loop GTPase; GPN-loop GTPase 1; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: GTPase activity. It is involved in the biological process described with: RNA polymerase II complex import to nucleus; RNA polymerase III complex localization to nucleus. 9 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; partially lethal; some die during pupal stage; some die during embryonic stage; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0260450	CalpC	-0.417720529	0.320032922	0.999936032	NA	CAPN9;CAPN10;CAPN2;CAPN3;CAPN11;CAPN1	moderate;high;moderate;low;low;low	NA	NA	NA	"The gene Calpain C is referred to in FlyBase by the symbol Dmel\CalpC (CG3692, FBgn0260450). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:16325763..16328523. It has the cytological map location 14B13. Protein features are: Calpain subdomain III; EF-hand domain; EF-hand domain pair; Peptidase C2, calpain family; Peptidase C2, calpain, catalytic domain; Peptidase C2, calpain, domain III; Peptidase C2, calpain, large subunit, domain III. Its molecular function is described by: calcium ion binding. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 12-18 embryonic stages, during late pupal stages.  "
FBgn0038790	MtnC	-0.417638342	0.232026597	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Metallothionein C is referred to in FlyBase by the symbol Dmel\MtnC (CG5097, FBgn0038790). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:20360308..20360634. It has the cytological map location 92E4. Protein features are: Metallothionein, family 5, Diptera. Its molecular function is described by: metal ion binding. It is involved in the biological process described with: metal ion homeostasis; response to metal ion. 10 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed in adult male stages.  "
FBgn0035321	CG1275	-0.417424822	0.233851755	0.999936032	NA	CYBRD1;CYB561;CYB561A3	high;moderate;moderate	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG1275 (FBgn0035321). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 3L:2252744..2257423. It has the cytological map location 62D4. Protein features are: Cytochrome b561/ferric reductase transmembrane. Its molecular function is described by: oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. 16 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: viable; body color defective; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed during late pupal stages.
FBgn0037943	CG14722	-0.417417514	0.26345873	0.999936032	WDR55	WDR55;IK	high;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14722 (FBgn0037943). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:11741890..11744027. It has the cytological map location 86E17. Protein features are: Anaphase-promoting complex subunit 4, WD40 domain; WD40 repeat; WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. It is involved in the biological process described with: ribosomal large subunit biogenesis; defense response to Gram-negative bacterium; rRNA processing. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0052280	CG32280	-0.417284621	0.247740263	0.999936032	NA	CDIP1	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32280 (FBgn0052280). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 3L:3165181..3169080. It has the cytological map location 63B8. Protein features are: LPS-induced tumour necrosis factor alpha factor. Its molecular function is described by: . It is involved in the biological process described with: . 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0032050	CG13096	-0.417026095	0.273740643	0.999936032	NA	RSL1D1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13096 (FBgn0032050). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:8509069..8511866. It has the cytological map location 29D3. Protein features are: Ribosomal protein L1, 3-layer alpha/beta-sandwich; Ribosomal protein L1-like; Ribosomal protein L1/ribosomal biogenesis protein. Its molecular function is described by: RNA binding. It is involved in the biological process described with: maturation of LSU-rRNA; translation. 4 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum. The phenotypic classes of alleles include: partially lethal; increased mortality during development; phenotype; some die during P-stage; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0052076	Alg10	-0.416982033	0.255793223	0.999936032	NA	ALG10B;ALG10	high;high	NA	transmembrane protein	NA	"The gene Alpha 3 glucosyltransferase is referred to in FlyBase by the symbol Dmel\Alg10 (CG32076, FBgn0052076). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:11164971..11166620. It has the cytological map location 68A9. Protein features are: Alpha-2-glucosyltransferase Alg10. Its molecular function is described by: dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity. It is involved in the biological process described with: dolichol-linked oligosaccharide biosynthetic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, during early pupal stages, in adult female stages.  "
FBgn0037489	CG1234	-0.416946852	0.275732157	0.999936032	NOC3L	NOC3L	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1234 (FBgn0037489). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:7244232..7246969. It has the cytological map location 84D3. Protein features are: Armadillo-like helical; Armadillo-type fold; CCAAT-binding factor; Nucleolar complex-associated protein 3; Nucleolar complex-associated protein 3, N-terminal. Its molecular function is described by: chromatin binding. The biological processes in which it is involved are not known. 6 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: partially lethal - majority die; partially lethal; lethal; visible; viable; lethal - all die during P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0036768	CG7402	-0.416377412	0.321163152	0.999936032	ARSB	ARSB;ARSI;ARSJ	high;moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7402 (FBgn0036768). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:17887705..17891404. It has the cytological map location 75A8. Protein features are: Alkaline phosphatase-like, alpha/beta/alpha; Alkaline-phosphatase-like, core domain; Sulfatase, N-terminal; Sulfatase, conserved site. Its molecular function is described by: sulfuric ester hydrolase activity. It is involved in the biological process described with: metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed during early pupal stages.  "
FBgn0034733	CG4752	-0.416374754	0.282622798	0.999936032	OPLAH	OPLAH	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4752 (FBgn0034733). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:22478379..22483054. It has the cytological map location 58E3. Protein features are: Hydantoinase B/oxoprolinase; Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase, N-terminal. Its molecular function is described by: 5-oxoprolinase (ATP-hydrolyzing) activity. It is involved in the biological process described with: glutathione metabolic process. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0000289	cg	-0.416028943	0.24220198	0.999936032	NA	ZNF786;ZNF467;ZNF425;REPIN1;ZNF444;ZNF76;PRDM15;ZNF837;ZNF442;ZSCAN32;ZNF143;ZNF417;ZNF628;ZNF697;ZNF142;ZNF17;ZNF18	low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene combgap is referred to in FlyBase by the symbol Dmel\cg (CG8367, FBgn0000289). It is a protein_coding_gene from Drosophila melanogaster. It has 11 annotated transcripts and 11 polypeptides (10 unique). Gene sequence location is 2R:14173693..14182838. It has the cytological map location 50E1. Protein features are: C2H2- zinc finger protein family subset; Myc-type, basic helix-loop-helix (bHLH) domain; Zinc finger C2H2-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: transcription factor activity, sequence-specific DNA binding; protein dimerization activity; nucleic acid binding. It is involved in the biological process described with: imaginal disc-derived wing morphogenesis; transcription, DNA-templated. 38 alleles are reported. The phenotypes of these alleles manifest in: imaginal disc; circulatory system; wing vein L5; antennal segment; larval tagma; digestive system; embryonic/larval circulatory system; salivary gland; embryonic/larval lymph gland; gland; ventral thoracic disc. The phenotypic classes of alleles include: increased mortality; phenotype; increased mortality during development; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, in adult female stages.  "
FBgn0035121	Tudor-SN	-0.415949369	0.230140615	0.999936032	SND1	SND1	high	NA	NA	NA	"The gene Tudor staphylococcal nuclease is referred to in FlyBase by the symbol Dmel\Tudor-SN (CG7008, FBgn0035121). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:259043..264380. It has the cytological map location 61B3. Protein features are: RNA-induced silencing complex, nuclease component Tudor-SN; Staphylococcal nuclease (SNase-like), OB-fold; Staphylococcal nuclease (SNase-like), OB-fold/extended TUDOR domain; Tudor domain. Its molecular function is described by: nuclease activity. It is involved in the biological process described with: negative regulation of transposition; gene silencing by RNA; spermatogenesis; RNA catabolic process. 28 alleles are reported. The phenotypes of these alleles manifest in: spermatogonium; spermatocyte; hub cell; testis; spermatid. The phenotypic classes of alleles include: increased cell number; fertile; cell cycle defective; viable; male semi-fertile; hyperplasia. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages, during early pupal stages, in adult female stages.  "
FBgn0028371	jbug	-0.415602256	0.322422826	0.999936032	NA	FLNA	moderate	NA	NA	NA	"The gene jitterbug is referred to in FlyBase by the symbol Dmel\jbug (CG30092, FBgn0028371). It is a protein_coding_gene from Drosophila melanogaster. It has 10 annotated transcripts and 10 polypeptides (6 unique). Gene sequence location is 2R:22717321..22740459. It has the cytological map location 59A3. Protein features are: Actinin-type actin-binding domain, conserved site; Calponin homology domain; Filamin/ABP280 repeat; Filamin/ABP280 repeat-like; Immunoglobulin E-set; Immunoglobulin-like fold. Its molecular function is described by: actin binding. It is involved in the biological process described with: response to mechanical stimulus; establishment of body hair or bristle planar orientation; photoreceptor cell axon guidance. 19 alleles are reported. The phenotypes of these alleles manifest in: eye photoreceptor cell; axon. The phenotypic classes of alleles include: viable; fertile; bang sensitive; planar polarity defective; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 12-24 hour embryonic stages, during late pupal stages.  "
FBgn0033092	CG9422	-0.415558304	0.271331272	0.999936032	NA	RPP25L;RPP25	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9422 (FBgn0033092). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:6675822..6693162. It has the cytological map location 42C4-42C5. Protein features are: DNA/RNA-binding protein Alba; DNA/RNA-binding protein Alba-like. Its molecular function is described by: RNA binding; ribonuclease P activity; DNA binding. It is involved in the biological process described with: cellular response to starvation; tRNA 5'-leader removal. 9 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; ganglion mother cell. The phenotypic classes of alleles include: lethal; viable; visible; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, during early larval stages, during early pupal stages, in adult female stages.  "
FBgn0032422	atilla	-0.415236191	0.244779597	0.999936032	NA	NA	NA	NA	NA	NA	"The gene atilla is referred to in FlyBase by the symbol Dmel\atilla (CG6579, FBgn0032422). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:12175451..12177886. It has the cytological map location 33D2-33D3. Its molecular function is described by: . It is involved in the biological process described with: . 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages.  "
FBgn0016715	Reg-2	-0.414886304	0.241136197	0.999936032	NA	HDHD3;NANP	moderate;low	NA	NA	NA	"The gene Rhythmically expressed gene 2 is referred to in FlyBase by the symbol Dmel\Reg-2 (CG3200, FBgn0016715). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:605165..606569. It has the cytological map location 61C7. Protein features are: HAD hydrolase, subfamily IA; HAD-like domain; HAD-superfamily hydrolase, subfamily IA, REG-2-like. Its molecular function is described by: hydrolase activity. It is involved in the biological process described with: metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late larval stages.  "
FBgn0038113	CG11668	-0.414227897	0.283022561	0.999936032	NA	F10;F7;MASP1;PROC	low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11668 (FBgn0038113). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:13038375..13040184. It has the cytological map location 87D9. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed during late larval stages, during early pupal stages, in adult male stages.  "
FBgn0003890	betaTub97EF	-0.413908733	0.230186955	0.999936032	NA	TUBB6;TUBB4B;TUBB2A;TUBB3;TUBB4A;TUBB;TUBB2B;TUBB8;TUBB1	moderate;moderate;high;moderate;moderate;moderate;low;moderate;low	NA	NA	NA	"The gene ‘_-Tubulin at 97EF is referred to in FlyBase by the symbol Dmel\‘_Tub97EF (CG4869, FBgn0003890). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:27967008..27988384. It has the cytological map location 98B6-98B7. Protein features are: Beta tubulin; Beta tubulin, autoregulation binding site; Tubulin; Tubulin, conserved site; Tubulin/FtsZ, 2-layer sandwich domain; Tubulin/FtsZ, C-terminal; Tubulin/FtsZ, GTPase domain. Its molecular function is described by: GTP binding; structural constituent of cytoskeleton; GTPase activity. It is involved in the biological process described with: microtubule-based process. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0052344	CG32344	-0.413737101	0.261248364	0.999936032	NA	DDX54	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32344 (FBgn0052344). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:321233..324720. It has the cytological map location 61C1. Protein features are: ATP-dependent RNA helicase DEAD-box, conserved site; DBP10, C-terminal; DDX54/DBP10 family; DEAD/DEAH box helicase domain; Helicase superfamily 1/2, ATP-binding domain; Helicase, C-terminal; P-loop containing nucleoside triphosphate hydrolase; RNA helicase, DEAD-box type, Q motif. Its molecular function is described by: helicase activity; ATP binding; ATP-dependent RNA helicase activity; RNA binding. It is involved in the biological process described with: RNA secondary structure unwinding. 3 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval neuroblast; ganglion mother cell. The phenotypic classes of alleles include: some die during pupal stage; lethal - all die before end of pupal stage; neuroanatomy defective; viable; lethal - all die during P-stage; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0039594	CG9990	-0.413218612	0.267671893	0.999936032	NA	ABCG2;ABCA3;ABCA12;ABCA5;ABCA10;ABCA2;ABCA4;ABCA13;ABCA1;ABCA6;ABCA8;ABCA7;ABCA9	low;low;low;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9990 (FBgn0039594). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (all unique). Gene sequence location is 3R:28675041..28695939. It has the cytological map location 98E1-98E2. Protein features are: AAA+ ATPase domain; ABC transporter, conserved site; ABC transporter-like; ABC-2 transporter; ABC-2 type transporter; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: ATP binding; ATPase activity. It is involved in the biological process described with: transport. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages.  "
FBgn0013269	FK506-bp1	-0.412790078	0.240574466	0.999936032	NA	FKBP15	high	NA	NA	NA	"The gene FK506-binding protein 1 is referred to in FlyBase by the symbol Dmel\FK506-bp1 (CG6226, FBgn0013269). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:15331584..15333133. It has the cytological map location 88F1. Protein features are: FK506-binding protein; FKBP-type peptidyl-prolyl cis-trans isomerase domain; Peptidyl-prolyl cis-trans isomerase, FKBP-type. Its molecular function is described by: juvenile hormone response element binding; protein binding; FK506 binding; peptidyl-prolyl cis-trans isomerase activity. It is involved in the biological process described with: juvenile hormone mediated signaling pathway; negative regulation of autophagy; histone peptidyl-prolyl isomerization; negative regulation of macroautophagy. 10 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval fat body; trichogen cell; mesothoracic tergum. The phenotypic classes of alleles include: increased mortality; lethal; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0027843	CAH2	-0.412718427	0.232007708	0.999936032	NA	CA7;CA14;CA4;CA12;CA6;CA9;CA2;CA5A;CA1;CA5B;CA8;CA3;CA13;PTPRG	moderate;high;low;moderate;moderate;moderate;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene Carbonic anhydrase 2 is referred to in FlyBase by the symbol Dmel\CAH2 (CG6906, FBgn0027843). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:12177601..12183347. It has the cytological map location 69A1. Protein features are: Alpha carbonic anhydrase; Carbonic anhydrase, alpha-class. Its molecular function is described by: carbonate dehydratase activity. It is involved in the biological process described with: one-carbon metabolic process. 9 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0035383	CPT2	-0.412678341	0.246521047	0.999936032	NA	CPT2	high	NA	NA	NA	"The gene Carnitine palmitoyltransferase 2 is referred to in FlyBase by the symbol Dmel\CPT2 (CG2107, FBgn0035383). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:2981022..2983551. It has the cytological map location 63A2. Protein features are: Acyltransferase ChoActase/COT/CPT. Its molecular function is described by: transferase activity, transferring acyl groups. It is involved in the biological process described with: fatty acid beta-oxidation; ketone body biosynthetic process; triglyceride homeostasis; response to starvation. 11 alleles are reported. The phenotypes of these alleles manifest in: flight muscle; adult brain; lipid particle. The phenotypic classes of alleles include: partially lethal - majority die; majority die during immature adult stage; short lived; starvation stress response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in stages of adults of both sexes.  "
FBgn0039595	AstA-R2	-0.412627372	0.27731682	0.999936032	NA	GALR1;GALR2;GALR3	high;low;moderate	NA	transmembrane protein	GPCR	"The gene Allatostatin A receptor 2 is referred to in FlyBase by the symbol Dmel\AstA-R2 (CG10001, FBgn0039595). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:28737109..28744782. It has the cytological map location 98E2-98E3. Protein features are: G protein-coupled receptor, rhodopsin-like; GPCR, rhodopsin-like, 7TM; Neuropeptide Y receptor family. Its molecular function is described by: allatostatin receptor activity; neuropeptide receptor activity; neuropeptide Y receptor activity; G-protein coupled receptor activity. It is involved in the biological process described with: G-protein coupled receptor signaling pathway; neuropeptide signaling pathway. 8 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: partially lethal - majority die; long lived; some die during pupal stage; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in adult male stages.  "
FBgn0039203	CG13618	-0.412547838	0.269104322	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG13618 (FBgn0039203). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:24524794..24527533. It has the cytological map location 96A5-96A6. Protein features are: Haemolymph juvenile hormone binding. Its molecular function is unknown. It is involved in the biological process described with: multicellular organism reproduction; circadian rhythm. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during early pupal stages.
FBgn0037146	CG7470	-0.411895755	0.22997761	0.999936032	ALDH18A1	ALDH18A1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7470 (FBgn0037146). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:21972002..21984606. It has the cytological map location 79A5-79A6. Protein features are: Aldehyde dehydrogenase N-terminal domain; Aldehyde dehydrogenase domain; Aldehyde/histidinol dehydrogenase; Aspartate/glutamate/uridylate kinase; Delta l-pyrroline-5-carboxylate synthetase; GPR domain; Gamma-glutamyl phosphate reductase GPR, conserved site; Glutamate 5-kinase, conserved site; Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase; Glutamate/acetylglutamate kinase. Its molecular function is described by: glutamate 5-kinase activity; delta1-pyrroline-5-carboxylate synthetase activity; glutamate-5-semialdehyde dehydrogenase activity. It is involved in the biological process described with: oxidation-reduction process; proline biosynthetic process; epithelium development; germarium-derived egg chamber formation. 5 alleles are reported. The phenotypes of these alleles manifest in: epithelium; egg chamber; interfollicle cell. The phenotypic classes of alleles include: viable; lethal - all die during P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, in adult male stages.  "
FBgn0031020	Naa15-16	-0.411332044	0.249242867	0.999936032	NA	NAA15;NAA16;LOC105377450	high;high;moderate	NA	NA	NA	"The gene N(alpha)-acetyltransferase 15/16 is referred to in FlyBase by the symbol Dmel\Naa15-16 (CG12202, FBgn0031020). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:19479984..19484643. It has the cytological map location 18C7. Protein features are: N-terminal acetyltransferase A, auxiliary subunit; Tetratricopeptide repeat; Tetratricopeptide repeat-containing domain; Tetratricopeptide-like helical domain. Its molecular function is described by: peptide alpha-N-acetyltransferase activity. It is involved in the biological process described with: N-terminal peptidyl-methionine acetylation. 10 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval neuroblast; ganglion mother cell. The phenotypic classes of alleles include: fertile; lethal; viable; lethal - all die during P-stage; lethal - all die during embryonic stage; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0036754	CG5589	-0.41080602	0.294459984	0.999936032	DDX52	DDX52	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5589 (FBgn0036754). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:17802490..17804715. It has the cytological map location 75A2. Protein features are: ATP-dependent RNA helicase DEAD-box, conserved site; DEAD/DEAH box helicase domain; Helicase superfamily 1/2, ATP-binding domain; Helicase, C-terminal; P-loop containing nucleoside triphosphate hydrolase; RNA helicase, DEAD-box type, Q motif. Its molecular function is described by: ATP binding; ATP-dependent RNA helicase activity; nucleic acid binding. It is involved in the biological process described with: RNA secondary structure unwinding; rRNA processing. 6 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: viable; lethal - all die during P-stage; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, during early larval stages.  "
FBgn0040529	COX7A	-0.410655175	0.23179669	0.999936032	NA	COX7A1;COX7A2;COX7A2L;COX7A2P2	moderate;high;moderate;moderate	NA	transmembrane protein	NA	"The gene Cytochrome c oxidase subunit 7A is referred to in FlyBase by the symbol Dmel\COX7A (CG9603, FBgn0040529). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:8339944..8341043. It has the cytological map location 84F13. Protein features are: Cytochrome c oxidase, subunit VIIa. Its molecular function is described by: cytochrome-c oxidase activity. It is involved in the biological process described with: mitochondrial electron transport, cytochrome c to oxygen. 8 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum. The phenotypic classes of alleles include: pain response defective; bang sensitive; locomotor behavior defective; lethal - all die during P-stage; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0262511	Vha44	-0.410188727	0.232032658	0.999936032	NA	ATP6V1C1;ATP6V1C2	high;moderate	NA	NA	NA	"The gene Vacuolar H<sup>+</sup> ATPase 44kD subunit is referred to in FlyBase by the symbol Dmel\Vha44 (CG8048, FBgn0262511). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is 2R:16324813..16336637. It has the cytological map location 53B3-53B4. Protein features are: ATPase, V1 complex, subunit C. Its molecular function is described by: hydrogen-exporting ATPase activity, phosphorylative mechanism; proton-transporting ATPase activity, rotational mechanism. It is involved in the biological process described with: proton transport; ATP hydrolysis coupled proton transport. 19 alleles are reported. The phenotypes of these alleles manifest in: wing disc; wing pouch; wing disc dorsal compartment; embryonic/larval somatic muscle. The phenotypic classes of alleles include: phenotype; increased mortality during development; increased mortality; lethal."
FBgn0033178	CG11127	-0.409718317	0.267595787	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG11127 (FBgn0033178). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:7463504..7464987. It has the cytological map location 43C3. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0017482	T3dh	-0.409589206	0.262994155	0.999936032	ADHFE1	ADHFE1	high	NA	NA	NA	"The gene Type III alcohol dehydrogenase is referred to in FlyBase by the symbol Dmel\T3dh (CG3425, FBgn0017482). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:22329726..22332072. It has the cytological map location 58D3. Protein features are: Alcohol dehydrogenase, iron-type. Its molecular function is described by: hydroxyacid-oxoacid transhydrogenase activity; metal ion binding; alcohol dehydrogenase (NAD) activity. It is involved in the biological process described with: molecular hydrogen transport; oxidation-reduction process. 7 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: fertile; visible; viable; flight defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout the larval period.  "
FBgn0264087	Slob	-0.409452983	0.326757304	0.999936032	NA	PXK	moderate	NA	transmembrane protein	NA	"The gene Slowpoke binding protein is referred to in FlyBase by the symbol Dmel\Slob (CG43756, FBgn0264087). It is a protein_coding_gene from Drosophila melanogaster. It has 11 annotated transcripts and 11 polypeptides (9 unique). Gene sequence location is 2L:7642005..7675078. It has the cytological map location 28B4-28C1. Protein features are: Protein kinase-like domain. Its molecular function is described by: protein binding; protein kinase activity. It is involved in the biological process described with: regulation of glucose metabolic process; response to starvation; modulation of synaptic transmission; neuromuscular synaptic transmission; regulation of membrane potential. 20 alleles are reported. The phenotype of these alleles manifest in: adult pars intercerebralis. The phenotypic classes of alleles include: fertile; stress response defective; viable; neurophysiology defective."
FBgn0022702	Cht2	-0.409438467	0.295074107	0.999936032	NA	CHIA;OVGP1;CHI3L2;CHI3L1;CHIT1	moderate;moderate;moderate;moderate;low	NA	NA	NA	"The gene Chitinase 2 is referred to in FlyBase by the symbol Dmel\Cht2 (CG2054, FBgn0022702). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3L:1752328..1755934. It has the cytological map location 62B1. Protein features are: Chitinase II; Chitinase insertion domain; Glycoside hydrolase family 18, catalytic domain; Glycoside hydrolase superfamily; Glycoside hydrolase, chitinase active site. Its molecular function is described by: chitinase activity; chitin binding. It is involved in the biological process described with: ecdysis, chitin-based cuticle; larval chitin-based cuticle development; chitin-based cuticle development; carbohydrate metabolic process; chitin-based embryonic cuticle biosynthetic process; wound healing; chitin catabolic process. 8 alleles are reported. The phenotypes of these alleles manifest in: wing; cuticular pore; mesothoracic tergum; third instar larval cuticle; assembly zone; dorsal trunk primordium; procuticle; pupal cuticle; embryonic/larval cuticle; embryonic/larval dorsal trunk. The phenotypic classes of alleles include: phenotype; increased mortality during development; viable; visible; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed during early pupal stages.  "
FBgn0250755	CG42233	-0.409298797	0.327616307	0.999936032	NA	DCAF5	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG42233 (FBgn0250755). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:31799634..31805278. It has the cytological map location 100D2. Protein features are: WD40 repeat; WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: . It is involved in the biological process described with: . 8 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0029839	CG4660	-0.408503121	0.292231293	0.999936032	NA	THEM6	moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4660 (FBgn0029839). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:6078708..6081372. It has the cytological map location 5D4. Protein features are: HotDog domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed during late pupal stages, in stages of adults of both sexes.  "
FBgn0263120	Acsl	-0.408251847	0.235593779	0.999936032	NA	ACSL4;ACSL3;ACSL5;ACSL1;ACSL6	high;high;low;low;low	NA	transmembrane protein	NA	"The gene Acyl-CoA synthetase long-chain is referred to in FlyBase by the symbol Dmel\Acsl (CG8732, FBgn0263120). It is a protein_coding_gene from Drosophila melanogaster. It has 10 annotated transcripts and 10 polypeptides (4 unique). Gene sequence location is 2R:8665813..8683022. It has the cytological map location 44D3-44D6. Protein features are: AMP-binding enzyme, C-terminal domain; AMP-binding, conserved site; AMP-dependent synthetase/ligase. Its molecular function is described by: palmitoyl-CoA ligase activity; long-chain fatty acid-CoA ligase activity. It is involved in the biological process described with 11 unique terms, many of which group under: negative regulation of signal transduction; regulation of lipid storage; neurogenesis; anterograde trans-synaptic signaling; early endosome to recycling endosome transport; organophosphate biosynthetic process; regulation of nervous system development; trans-synaptic signaling; localization; regulation of growth; organic cyclic compound biosynthetic process; cell morphogenesis involved in neuron differentiation; establishment of localization; organophosphate metabolic process. 49 alleles are reported. The phenotypes of these alleles manifest in: somatic precursor cell; region of integument; embryonic/larval neuroblast; embryonic abdominal segment 2; cell projection; cell part; cell; ganglion; plasma membrane bounded cell projection; abdominal segment 7; tergum. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; pain response defective; phenotype; viable; increased mortality during development; lethal."
FBgn0035501	CG1299	-0.407360343	0.329200773	0.999936032	NA	PRSS12;CTRB1;CELA3A;CELA1;CTRB2;CELA2A;CTRC;CELA3B;CELA2B;CTRL	low;low;low;low;low;low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1299 (FBgn0035501). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:4148696..4152473. It has the cytological map location 64A8. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Proteinase, regulatory CLIP domain; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 8 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during late larval stages, at stages throughout the pupal period.  "
FBgn0053965	CG33965	-0.407314652	0.249062028	0.999936032	NA	TTPAL;CLVS1;RLBP1;CLVS2;TTPA	moderate;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG33965 (FBgn0053965). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:1232882..1234015. It has the cytological map location 61F4. Protein features are: CRAL-TRIO lipid binding domain; CRAL/TRIO, N-terminal domain; Cellular retinaldehyde binding/alpha-tocopherol transport; Cyclic nucleotide-binding domain. Its molecular function is described by: transporter activity. It is involved in the biological process described with: transport. 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the larval period.  "
FBgn0038419	CG14879	-0.407135119	0.255163232	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14879 (FBgn0038419). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3R:16345825..16349226. It has the cytological map location 89B13. Protein features are: Concanavalin A-like lectin/glucanase domain; Galectin, carbohydrate recognition domain. Its molecular function is described by: carbohydrate binding. The biological processes in which it is involved are not known. 14 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 06-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0005672	spi	-0.40693646	0.269595525	0.999936032	NA	TRADD	low	NA	transmembrane protein	NA	"The gene spitz is referred to in FlyBase by the symbol Dmel\spi (CG10334, FBgn0005672). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is 2L:19567900..19577315. It has the cytological map location 37F2. Protein features are: EGF-like domain; EGF-like, conserved site. Its molecular function is described by: epidermal growth factor receptor binding. It is involved in the biological process described with 26 unique terms, many of which group under: enzyme linked receptor protein signaling pathway; ERBB signaling pathway; nuclear division; ovarian follicle cell development; stem cell differentiation; peripheral nervous system development; heart process; post-embryonic animal organ morphogenesis; negative regulation of macromolecule metabolic process; cell cycle G2/M phase transition; apoptotic process; neurological system process; branched duct epithelial cell fate determination, open tracheal system; regulation of cell communication; wing disc morphogenesis; circulatory system process. 93 alleles are reported. The phenotypes of these alleles manifest in: chorionic specialization; hemocoel; external encapsulating structure; interneuron; wing blade; germline stem cell; germline cyst; ganglion mother cell; rhabdomere; germ layer. The phenotypic classes of alleles include: lethal - all die before end of P-stage; increased mortality; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0264915	CR44106	-0.406258656	0.26620588	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44106 (FBgn0264915). It is a non_protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts. Gene sequence location is 3R:20911640..20912869. It has the cytological map location 93A3. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available.
FBgn0034485	CG11099	-0.406239868	0.246525239	0.999936032	NA	LRRC18	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11099 (FBgn0034485). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:20236235..20239200. It has the cytological map location 56F10-56F11. Protein features are: Leucine-rich repeat; Leucine-rich repeat domain, L domain-like; Leucine-rich repeat, typical subtype. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed during late pupal stages, in stages of adults of both sexes.  "
FBgn0027528	goe	-0.406073401	0.280597523	0.999936032	NA	ECE2;ECE1;KEL;PHEX;ECEL1	moderate;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene gone early is referred to in FlyBase by the symbol Dmel\goe (CG9634, FBgn0027528). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:16727304..16751910. It has the cytological map location 15A3-15A5. Protein features are: Peptidase M13; Peptidase M13, N-terminal domain. Its molecular function is described by: metalloendopeptidase activity. It is involved in the biological process described with: oogenesis; proteolysis; negative regulation of stem cell differentiation. 15 alleles are reported. The phenotypes of these alleles manifest in: female germline cyst; wing; female germline cell; cystoblast. The phenotypic classes of alleles include: fertile; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0050491	CG30491	-0.405782158	0.293030854	0.999936032	NA	RDH13;RDH12;RDH11;RDH14;DHRS13;DHRSX	high;moderate;moderate;moderate;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG30491 (FBgn0050491). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:7655072..7656770. It has the cytological map location 43E7. Protein features are: NAD(P)-binding domain; Short-chain dehydrogenase/reductase SDR. Its molecular function is described by: oxidoreductase activity. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0262559	Mdh2	-0.405747381	0.23595809	0.999936032	NA	MDH2	high	NA	NA	NA	"The gene Malate dehydrogenase 2 is referred to in FlyBase by the symbol Dmel\Mdh2 (CG7998, FBgn0262559). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:18226396..18228718. It has the cytological map location 90F8-90F9. Protein features are: L-lactate/malate dehydrogenase; Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal; Lactate/malate dehydrogenase, C-terminal; Lactate/malate dehydrogenase, N-terminal; Malate dehydrogenase, type 1; NAD(P)-binding domain. Its molecular function is described by: L-malate dehydrogenase activity; malate dehydrogenase activity. It is involved in the biological process described with: larval midgut cell programmed cell death; salivary gland histolysis; regulation of programmed cell death; pupal development; tricarboxylic acid cycle; positive regulation of programmed cell death; activation of cysteine-type endopeptidase activity involved in apoptotic process; carbohydrate metabolic process; salivary gland cell autophagic cell death. 19 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval midgut; wing; embryonic/larval salivary gland. The phenotypic classes of alleles include: increased mortality during development; phenotype; lethal; increased mortality."
FBgn0263112	Mitf	-0.40506106	0.248011895	0.999936032	NA	MITF;TFEB;TFEC;TFE3	high;moderate;moderate;moderate	Co-factor(HLH)	NA	NA	"The gene Mitf is referred to in FlyBase by the symbol Dmel\Mitf (CG43369, FBgn0263112). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 4:1198852..1224467. It has the cytological map location 102F8. Protein features are: MiT/TFE transcription factors, N-terminal; Myc-type, basic helix-loop-helix (bHLH) domain. Its molecular function is described by: protein dimerization activity; sequence-specific DNA binding. It is involved in the biological process described with: positive regulation of transcription, DNA-templated; lipid catabolic process; positive regulation of autophagosome maturation; cellular response to starvation; regulation of transcription, DNA-templated; lysosome organization; compound eye morphogenesis. 20 alleles are reported. The phenotypes of these alleles manifest in: fat body; lysosome; autophagosome; wing; mitochondrion; wing disc; eye disc; adult brain. The phenotypic classes of alleles include: visible; lethal - all die before end of larval stage; starvation stress response defective; some die during larval stage; neuroanatomy defective."
FBgn0046222	Wdr33	-0.405051586	0.295003117	0.999936032	NA	WDR33	high	NA	NA	NA	"The gene WD repeat domain 33 is referred to in FlyBase by the symbol Dmel\Wdr33 (CG1109, FBgn0046222). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:5660635..5665169. It has the cytological map location 83B8. Protein features are: G-protein beta WD-40 repeat; WD40 repeat; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. It is involved in the biological process described with: mRNA cleavage; neuron projection morphogenesis; mRNA polyadenylation. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; female sterile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0038829	CG17271	-0.404532419	0.241350802	0.999936032	NA	MCFD2	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17271 (FBgn0038829). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:20819129..20821848. It has the cytological map location 93A1. Protein features are: EF-Hand 1, calcium-binding site; EF-hand domain; EF-hand domain pair. Its molecular function is described by: calcium ion binding. It is involved in the biological process described with: multicellular organism reproduction. 8 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0023511	Edem1	-0.404508406	0.30844179	0.999936032	EDEM2	EDEM2;EDEM1	high;moderate	NA	transmembrane protein	NA	"The gene ER degradation enhancer, mannosidase alpha-like 1 is referred to in FlyBase by the symbol Dmel\Edem1 (CG3810, FBgn0023511). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (2 unique). Gene sequence location is X:1903704..1908827. It has the cytological map location 2B15. Protein features are: Glycoside hydrolase family 47. Its molecular function is described by: mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; calcium ion binding. It is involved in the biological process described with: N-glycan processing; ubiquitin-dependent ERAD pathway; ubiquitin-dependent glycoprotein ERAD pathway; endoplasmic reticulum unfolded protein response; determination of adult lifespan. 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: long lived; partially lethal - majority die; some die during pharate adult stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0028527	CG18507	-0.404480564	0.323352562	0.999936032	NA	TMEM268	high	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG18507 (FBgn0028527). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (all unique). Gene sequence location is 2L:13665525..13672967. It has the cytological map location 34C6. Protein features are: Protein of unknown function DUF4481. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 06-18 hour embryonic stages.
FBgn0031265	CG2794	-0.404102168	0.290653719	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG2794 (FBgn0031265). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:564163..566472. It has the cytological map location 21E2. Protein features are: Carbohydrate kinase PfkB; Carbohydrate/puine kinase, PfkB, conserved site; Pseudouridine-5'-phosphate glycosidase; Ribokinase-like. Its molecular function is described by: hydrolase activity, acting on glycosyl bonds; phosphotransferase activity, alcohol group as acceptor. It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed during early larval stages, in adult male stages.  "
FBgn0030912	CG6023	-0.403749374	0.336167103	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG6023 (FBgn0030912). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:18314124..18321193. It has the cytological map location 17A5. Its molecular function is unknown. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0261808	cu	-0.40327105	0.267801964	0.999936032	NA	NOCT;PDE12	high;low	NA	NA	NA	"The gene curled is referred to in FlyBase by the symbol Dmel\cu (CG31299, FBgn0261808). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (all unique). Gene sequence location is 3R:11197592..11208633. It has the cytological map location 86D7. Protein features are: Endonuclease/exonuclease/phosphatase. Its molecular function is unknown. It is involved in the biological process described with: nuclear-transcribed mRNA poly(A) tail shortening; response to light stimulus; locomotor rhythm. 24 alleles are reported. The phenotypes of these alleles manifest in: posterior scutellar bristle; wing. The phenotypic classes of alleles include: lethal; stress response defective; phenotype; increased mortality during development."
FBgn0031737	obst-E	-0.40323156	0.322393621	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene obstructor-E is referred to in FlyBase by the symbol Dmel\obst-E (CG11142, FBgn0031737). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:5762553..5766142. It has the cytological map location 25F4. Protein features are: Chitin binding domain. Its molecular function is described by: chitin binding. It is involved in the biological process described with: chitin metabolic process. 13 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval hindgut; anterior pupal spiracle; third instar larval cuticle; procuticle. The phenotypic classes of alleles include: body size defective; lethal - all die before end of first instar larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages.  "
FBgn0030828	CG5162	-0.403214103	0.266323997	0.999936032	NA	PNLIPRP2;PNLIP;LIPH;PLA1A;PNLIPRP1;LIPI;PNLIPRP3;LIPG;LPL;LIPC	low;low;low;low;low;low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5162 (FBgn0030828). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:17215304..17217365. It has the cytological map location 15F4. Protein features are: Alpha/Beta hydrolase fold; Lipase, N-terminal; Lipase/vitellogenin; Triacylglycerol lipase family. Its molecular function is described by: carboxylic ester hydrolase activity; lipase activity. It is involved in the biological process described with: multicellular organism reproduction; lipid catabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during late pupal stages, in adult male stages.  "
FBgn0001145	Gs2	-0.403170776	0.237934627	0.999936032	NA	GLUL	high	NA	NA	NA	"The gene Glutamine synthetase 2 is referred to in FlyBase by the symbol Dmel\Gs2 (CG1743, FBgn0001145). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (4 unique). Gene sequence location is X:11422832..11430197. It has the cytological map location 10B11. Protein features are: Glutamine synthetase, N-terminal conserved site; Glutamine synthetase, beta-Grasp domain; Glutamine synthetase, catalytic domain; Glutamine synthetase, glycine-rich site; Glutamine synthetase/guanido kinase, catalytic domain. Its molecular function is described by: glutamate-ammonia ligase activity. It is involved in the biological process described with: glutamine biosynthetic process; synapse assembly; glutamate catabolic process; neurotransmitter receptor metabolic process. 13 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: short lived; neurophysiology defective; viable; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0037231	Vps24	-0.402687922	0.266615124	0.999936032	NA	CHMP3;RNF103-CHMP3;RNF103	high;moderate;moderate	NA	NA	NA	"The gene Vacuolar protein sorting 24 is referred to in FlyBase by the symbol Dmel\Vps24 (CG9779, FBgn0037231). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:4307435..4310947. It has the cytological map location 82A3. Protein features are: Snf7 family. Its molecular function is described by: . It is involved in the biological process described with: vacuolar transport; phagocytosis; intralumenal vesicle formation. 6 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; myofibril; mesothoracic tergum. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; flightless; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0035039	Adck	-0.402427055	0.301311596	0.999936032	NA	ADCK1;ADCK5	high;low	NA	NA	NA	"The gene aarF domain containing kinase is referred to in FlyBase by the symbol Dmel\Adck (CG3608, FBgn0035039). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:24611703..24613906. It has the cytological map location 60D9. Protein features are: Protein kinase domain; Protein kinase-like domain; UbiB domain. Its molecular function is described by: ATP binding; protein kinase activity. It is involved in the biological process described with: positive regulation of peptide hormone secretion; mitochondrion organization; lipid homeostasis; positive regulation of multicellular organism growth; protein phosphorylation. 8 alleles are reported. The phenotypes of these alleles manifest in: embryo; trichogen cell. The phenotypic classes of alleles include: small body; viable; female semi-sterile; visible; female sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 12-18 embryonic stages.  "
FBgn0263133	mEFG1	-0.402401093	0.295493974	0.999936032	NA	GFM1;GFM2	high;low	NA	NA	NA	"The gene mitochondrial translation elongation factor G 1 is referred to in FlyBase by the symbol Dmel\mEFG1 (CG4567, FBgn0263133). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:7220369..7223081. It has the cytological map location 27C7-27D2. Protein features are: EF-G domain III/V-like; EFG, domain V; Elongation factor EFG, domain V-like; Elongation factor G, domain III; P-loop containing nucleoside triphosphate hydrolase; Ribosomal protein S5 domain 2-type fold; Ribosomal protein S5 domain 2-type fold, subgroup; Small GTP-binding protein domain; Tr-type G domain, conserved site; Transcription factor, GTP-binding domain; Translation elongation factor EFG/EF2; Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFTu-like, domain 2; Translation protein, beta-barrel domain. Its molecular function is described by: translation elongation factor activity; GTPase activity; GTP binding. It is involved in the biological process described with: mitochondrial translational elongation. 23 alleles are reported. The phenotypes of these alleles manifest in: eye; trichogen cell; macrochaeta; wing vein; wing. The phenotypic classes of alleles include: lethal - all die before end of P-stage; increased mortality during development; phenotype; lethal."
FBgn0266450	Kr-h1	-0.402092748	0.263452233	0.999936032	NA	GTF3A;ZNF658;ZFP1;ZNF32;BCL11B;ZNF169;ZNF132;BCL6B;ZNF143;ZNF530;ZNF417;ZBTB7A;ZNF358;ZNF131;ZBTB49;ZNF418;ZSCAN10;GFI1;REPIN1;ZBTB17;ZBTB47;ZBTB48;ZBTB16;PATZ1;GLI4;ZNF467;ZBTB7B;ZNF835;ZNF569;ZBTB41;GFI1B;ZNF652;ZBTB11;ZBTB7C;ZBTB24	low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene Kruppel homolog 1 is referred to in FlyBase by the symbol Dmel\Kr-h1 (CG45074, FBgn0266450). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:6082603..6096498. It has the cytological map location 26B5. Protein features are: Zinc finger C2H2-type. Its molecular function is described by: transcription factor activity, sequence-specific DNA binding; nucleic acid binding. It is involved in the biological process described with: negative regulation of compound eye photoreceptor development; metamorphosis; regulation of transcription, DNA-templated; negative regulation of neuron projection development; response to ecdysone. 27 alleles are reported. The phenotypes of these alleles manifest in: compound sense organ; cell; embryonic/larval anterior spiracle; peripheral nervous system; embryonic/larval mouth; adult head; prepupa; pigment cell; eye; somatic cell; intersegmental nerve; ventral nerve cord commissure. The phenotypic classes of alleles include: lethal; phenotype; increased mortality during development; lethal - all die before end of pupal stage."
FBgn0034528	CG11180	-0.40181557	0.292446523	0.999936032	NA	PINX1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11180 (FBgn0034528). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:20620914..20623429. It has the cytological map location 57A7-57A8. Protein features are: G-patch domain. Its molecular function is described by: nucleic acid binding. The biological processes in which it is involved are not known. 5 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; ganglion mother cell; embryonic/larval neuroblast. The phenotypic classes of alleles include: neuroanatomy defective; viable; visible; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, in adult female stages.  "
FBgn0035636	Cralbp	-0.401727613	0.33747109	0.999936032	NA	CLVS1;RLBP1;CLVS2;SEC14L4;TTPAL;TTPA	moderate;high;high;low;low;low	NA	NA	NA	"The gene Cellular retinaldehyde binding protein is referred to in FlyBase by the symbol Dmel\Cralbp (CG10546, FBgn0035636). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:5783215..5786718. It has the cytological map location 64E8. Protein features are: CRAL-TRIO lipid binding domain; CRAL/TRIO, N-terminal domain; Cellular retinaldehyde binding/alpha-tocopherol transport. Its molecular function is described by: transporter activity; retinal binding. It is involved in the biological process described with: transport. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages.  "
FBgn0030897	Frq1	-0.401665577	0.334207082	0.999936032	NA	NCS1;HPCA;HPCAL1;KCNIP4;KCNIP3;VSNL1;KCNIP1;KCNIP2;HPCAL4;RCVRN	high;low;low;low;low;low;low;low;low;low	NA	NA	NA	"The gene Frequenin 1 is referred to in FlyBase by the symbol Dmel\Frq1 (CG5744, FBgn0030897). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is X:18155369..18174744. It has the cytological map location 16F7-17A1. Protein features are: EF-Hand 1, calcium-binding site; EF-hand domain; EF-hand domain pair. Its molecular function is described by: calcium sensitive guanylate cyclase activator activity; calcium ion binding. It is involved in the biological process described with: chemical synaptic transmission; regulation of neurotransmitter secretion; neuromuscular junction development; neurotransmitter secretion. 8 alleles are reported. The phenotypes of these alleles manifest in: bouton; type I bouton; embryonic/larval neuromuscular junction; motor neuron; NMJ bouton. The phenotypic classes of alleles include: viable; neurophysiology defective; locomotor behavior defective; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0033289	CG2121	-0.401261396	0.338683553	0.999936032	NA	UNC93A;UNC93B1	moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG2121 (FBgn0033289). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:8396397..8411767. It has the cytological map location 44C4-44C6. Protein features are: Ion channel regulatory protein, UNC-93; Major facilitator superfamily domain. Its molecular function is described by: potassium channel regulator activity. It is involved in the biological process described with: regulation of potassium ion transport; regulation of muscle contraction; skeletal muscle contraction. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0261504	7SLRNA:CR42652	-0.401241578	0.315488179	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Signal recognition particle 7SL RNA CR42652 is referred to in FlyBase by the symbol Dmel\7SLRNA:CR42652 (CR42652, FBgn0261504). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3R:6820133..6820431. It has the cytological map location 84A5. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0031800	CG9497	-0.400801167	0.315019935	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9497 (FBgn0031800). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:6346430..6348427. It has the cytological map location 26C3. Protein features are: CHK kinase-like; Protein kinase-like domain; Protein of unknown function DUF227. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. The phenotypes of these alleles manifest in: lipid particle; embryonic/larval fat body. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0259175	ome	-0.400471433	0.244961373	0.999936032	NA	FAP;DPP4;DPP10;DPP6	high;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene omega is referred to in FlyBase by the symbol Dmel\ome (CG42280, FBgn0259175). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 3L:14672839..14747868. It has the cytological map location 70E7-70E8. Protein features are: Alpha/Beta hydrolase fold; Dipeptidylpeptidase IV, N-terminal domain; Peptidase S9, prolyl oligopeptidase, catalytic domain. Its molecular function is described by: serine-type peptidase activity; dipeptidyl-peptidase activity. It is involved in the biological process described with: proteolysis. 26 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; male semi-sterile; fertile; developmental rate defective; small body. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-18 embryonic stages, during late pupal stages.  "
FBgn0000723	FER	-0.400385222	0.271746317	0.999936032	NA	FER;FES	high;moderate	NA	NA	NA	"The gene FER tyrosine kinase is referred to in FlyBase by the symbol Dmel\FER (CG8874, FBgn0000723). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (all unique). Gene sequence location is 3R:9367603..9394546. It has the cytological map location 85D13-85D15. Protein features are: Arfaptin homology (AH) domain/BAR domain; F-BAR domain; FCH domain; Protein kinase domain; Protein kinase, ATP binding site; Protein kinase-like domain; SH2 domain; Serine-threonine/tyrosine-protein kinase, catalytic domain; Tyrosine-protein kinase, Fes/Fps type; Tyrosine-protein kinase, active site; Tyrosine-protein kinase, catalytic domain. Its molecular function is described by: protein tyrosine kinase activity; phospholipid binding; receptor binding; ATP binding; non-membrane spanning protein tyrosine kinase activity. It is involved in the biological process described with 12 unique terms, many of which group under: immune system process; cellular component biogenesis; signal transduction; neuron projection morphogenesis; peptidyl-tyrosine phosphorylation; actin filament bundle organization; cell motility; actin filament organization; cell surface receptor signaling pathway; growth; dorsal closure, amnioserosa morphology change; response to chemical; immune response; cell migration. 22 alleles are reported. The phenotypes of these alleles manifest in: amnioserosa; embryo; ventral midline. The phenotypic classes of alleles include: female semi-sterile; lethal - all die before end of embryonic stage; viable; fertile; some die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 06-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0262728	Pal2	-0.400073648	0.281172882	0.999936032	NA	PAM	high	NA	NA	NA	"The gene Peptidyl-‘±-hydroxyglycine-‘±-amidating lyase 2 is referred to in FlyBase by the symbol Dmel\Pal2 (CG5472, FBgn0262728). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:23688077..23690838. It has the cytological map location 59F6. Protein features are: NHL repeat; NHL repeat, subgroup; Six-bladed beta-propeller, TolB-like. Its molecular function is described by: peptidylamidoglycolate lyase activity. It is involved in the biological process described with: cellular metabolic process. 5 alleles are reported. No phenotypic data is available. No phenotypic class data is available."
FBgn0026666	MagR	-0.399363865	0.291185758	0.999936032	NA	ISCA1	high	NA	NA	NA	"The gene Magnetic receptor is referred to in FlyBase by the symbol Dmel\MagR (CG8198, FBgn0026666). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:15734270..15735780. It has the cytological map location 13E12. Protein features are: FeS cluster biogenesis; FeS cluster insertion protein; FeS cluster insertion, C-terminal, conserved site. Its molecular function is described by: iron-sulfur cluster binding; structural molecule activity. It is involved in the biological process described with: response to magnetism; protein maturation by iron-sulfur cluster transfer. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; locomotor rhythm defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed in adult male stages.  "
FBgn0036551	CG17029	-0.399288959	0.252636764	0.999936032	NA	IMPA1;IMPA2	moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17029 (FBgn0036551). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:15976870..15978435. It has the cytological map location 72C1. Protein features are: Inositol monophosphatase; Inositol monophosphatase, Lithium-sensitive; Inositol monophosphatase, conserved site; Inositol monophosphatase, metal-binding site; Inositol monophosphatase-like. Its molecular function is described by: inositol monophosphate 1-phosphatase activity. It is involved in the biological process described with: phosphatidylinositol phosphorylation; inositol metabolic process; dephosphorylation; inositol phosphate dephosphorylation; signal transduction. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die during P-stage; viable; some die during pupal stage; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0038100	Paip2	-0.398979489	0.277581489	0.999936032	NA	PAIP2B;PAIP2	high;high	NA	NA	NA	"The gene polyA-binding protein interacting protein 2 is referred to in FlyBase by the symbol Dmel\Paip2 (CG12358, FBgn0038100). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:12980792..12985488. It has the cytological map location 87D6-87D7. Protein features are: Ataxin-2, C-terminal. Its molecular function is described by: protein binding. It is involved in the biological process described with: negative regulation of translation; regulation of cell growth. 4 alleles are reported. The phenotypes of these alleles manifest in: wing disc; ommatidium; wing; indirect flight muscle; sarcomere; myofibril; embryonic/larval fat body; Z disc. The phenotypic classes of alleles include: phenotype; visible; increased mortality; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0037051	CG10565	-0.398725585	0.257892532	0.999936032	DNAJC2	DNAJC2	high	DNA-binding with transcription factor activity(Myb_DNA-binding)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10565 (FBgn0037051). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:21133250..21136353. It has the cytological map location 78B2-78B3. Protein features are: DnaJ domain; Homeobox domain-like; Myb-like domain; Ribosome-associated complex head domain; SANT/Myb domain. Its molecular function is described by: DNA binding. The biological processes in which it is involved are not known. 9 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; wing. The phenotypic classes of alleles include: viable; flight defective; visible; lethal; lethal - all die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-12 hour embryonic stages, during early larval stages.  "
FBgn0040513	kappaB-Ras	-0.398655885	0.289275952	0.999936032	NA	NKIRAS1;NKIRAS2	high;moderate	NA	NA	NA	"The gene ‘_B-Ras is referred to in FlyBase by the symbol Dmel\‘_B-Ras (CG1669, FBgn0040513). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:7443824..7445792. It has the cytological map location 43C1. Protein features are: P-loop containing nucleoside triphosphate hydrolase; Small GTPase superfamily; Small GTPase superfamily, Ras type. Its molecular function is described by: GTPase activity; GTP binding; protein binding. It is involved in the biological process described with: negative regulation of I-kappaB kinase/NF-kappaB signaling; signal transduction. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0037336	CG2519	-0.398350692	0.296735799	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG2519 (FBgn0037336). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:5539510..5547775. It has the cytological map location 83B1. Its molecular function is described by: . It is involved in the biological process described with: . 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0030594	CG9509	-0.398142508	0.244965529	0.999936032	NA	CHDH	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9509 (FBgn0030594). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:14906334..14909708. It has the cytological map location 13A1. Protein features are: FAD/NAD(P)-binding domain; Glucose-methanol-choline oxidoreductase; Glucose-methanol-choline oxidoreductase, C-terminal; Glucose-methanol-choline oxidoreductase, N-terminal. Its molecular function is described by: flavin adenine dinucleotide binding; oxidoreductase activity, acting on CH-OH group of donors; oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process; mesoderm development; ecdysteroid metabolic process. 4 alleles are reported. The phenotypes of these alleles manifest in: male accessory gland secondary cell; vacuole. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during late larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0036821	CG3961	-0.397579122	0.290372221	0.999936032	ACSL5	ACSL5;ACSL6;ACSL1;ACSL4;ACSL3	high;moderate;moderate;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3961 (FBgn0036821). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 3L:18878250..18890483. It has the cytological map location 75E3-75E4. Protein features are: AMP-binding enzyme, C-terminal domain; AMP-binding, conserved site; AMP-dependent synthetase/ligase. Its molecular function is described by: long-chain fatty acid-CoA ligase activity. It is involved in the biological process described with: long-chain fatty acid metabolic process. 13 alleles are reported. The phenotype of these alleles manifest in: female germline stem cell. The phenotypic classes of alleles include: fertile; flightless; viable; increased cell death. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during late larval stages, during late pupal stages.  "
FBgn0034802	CNBP	-0.397553828	0.254367384	0.999936032	NA	CNBP;ZCCHC13	high;moderate	NA	NA	NA	"The gene CCHC-type zinc finger nucleic acid binding protein is referred to in FlyBase by the symbol Dmel\CNBP (CG3800, FBgn0034802). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:22934569..22937077. It has the cytological map location 59B6. Protein features are: Zinc finger, CCHC-type. Its molecular function is described by: nucleic acid binding; zinc ion binding. It is involved in the biological process described with: . 12 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; wing vein; wing; trichogen cell. The phenotypic classes of alleles include: size defective; lethal - all die before end of pupal stage; visible; lethal - all die during P-stage; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.  "
FBgn0036500	CG7275	-0.396647677	0.280724835	0.999936032	DCAF13	DCAF13	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7275 (FBgn0036500). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:15498959..15500561. It has the cytological map location 71D3. Protein features are: Sof1-like protein; WD40 repeat; WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. It is involved in the biological process described with: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); phagocytosis. 4 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; embryonic/larval neuroblast; mesothoracic tergum. The phenotypic classes of alleles include: partially lethal; increased mortality; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0011211	blw	-0.396590728	0.24447347	0.999936032	NA	ATP5A1	high	NA	NA	NA	"The gene bellwether is referred to in FlyBase by the symbol Dmel\blw (CG3612, FBgn0011211). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:22799099..22802180. It has the cytological map location 59B1-59B2. Protein features are: ATP synthase subunit alpha-like domain; ATP synthase, F1 complex, alpha subunit; ATP synthase, F1 complex, alpha subunit nucleotide-binding domain; ATP synthase, alpha subunit, C-terminal; ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain; ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain; ATPase, alpha/beta subunit, nucleotide-binding domain, active site; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: proton-transporting ATP synthase activity, rotational mechanism; ATP binding. It is involved in the biological process described with: regulation of choline O-acetyltransferase activity; electron transport chain; lipid storage; spermatid development; proton transport; ATP synthesis coupled proton transport; phagocytosis; growth. 32 alleles are reported. The phenotypes of these alleles manifest in: dorsal medial muscle; mitochondrion; mesothoracic tergum; wing disc; vacuole; spermatid; embryonic/larval fat body. The phenotypic classes of alleles include: visible; male sterile; phenotype; increased mortality during development; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0038989	CG6937	-0.396002336	0.290767834	0.999936032	NA	NIFK	high	Maybe TF	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6937 (FBgn0038989). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:22584773..22586209. It has the cytological map location 94B5. Protein features are: RNA recognition motif domain. Its molecular function is described by: nucleic acid binding; mRNA binding. The biological processes in which it is involved are not known. 5 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval neuroblast; ganglion mother cell. The phenotypic classes of alleles include: lethal - all die during P-stage; viable; lethal; some die during pupal stage; lethal - all die before end of pupal stage; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0038440	Gr89a	-0.396001176	0.339247981	0.999936032	NA	NA	NA	NA	transmembrane protein	GPCR	"The gene Gustatory receptor 89a is referred to in FlyBase by the symbol Dmel\Gr89a (CG14901, FBgn0038440). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:16497817..16498959. It has the cytological map location 89B18. Protein features are: 7TM chemoreceptor. Its molecular function is described by: taste receptor activity. It is involved in the biological process described with: detection of chemical stimulus involved in sensory perception of taste. 3 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very low expression to a trough of no expression detected.  Peak expression observed during early pupal stages, in adult male stages.  "
FBgn0017558	Pdk	-0.395961565	0.252652163	0.999936032	NA	PDK3;PDK2;PDK1;PDK4	high;moderate;moderate;moderate	NA	NA	NA	"The gene Pyruvate dehydrogenase kinase is referred to in FlyBase by the symbol Dmel\Pdk (CG8808, FBgn0017558). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 2R:9426439..9434638. It has the cytological map location 45D5-45D7. Protein features are: Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal; Histidine kinase domain; Histidine kinase-like ATPase, C-terminal domain. Its molecular function is described by: protein kinase activity; pyruvate dehydrogenase (acetyl-transferring) kinase activity. It is involved in the biological process described with: pyruvate metabolic process. 14 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; female semi-sterile; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, during late larval stages, during late pupal stages.  "
FBgn0034580	Cht8	-0.395644095	0.2499319	0.999936032	NA	CHI3L1;CHIA;CHIT1;OVGP1;CHI3L2	moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"The gene Chitinase 8 is referred to in FlyBase by the symbol Dmel\Cht8 (CG9357, FBgn0034580). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:21061646..21063212. It has the cytological map location 57B16. Protein features are: Chitin binding domain; Chitinase II; Chitinase insertion domain; Glycoside hydrolase family 18, catalytic domain; Glycoside hydrolase superfamily; Glycoside hydrolase, chitinase active site. Its molecular function is described by: chitin binding; chitinase activity. It is involved in the biological process described with: carbohydrate metabolic process; ecdysis, chitin-based cuticle; chitin catabolic process. 4 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval cuticle. The phenotypic classes of alleles include: viable; partially lethal - majority live; some die during larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during early pupal stages.  "
FBgn0051200	CG31200	-0.395617906	0.257658842	0.999936032	NA	PAMR1	low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31200 (FBgn0051200). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:20744234..20745338. It has the cytological map location 92F10. Protein features are: Peptidase S1, PA clan; Serine proteases, trypsin domain. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0036005	pall	-0.395561437	0.304568066	0.999936032	NA	FBXO28	high	NA	NA	NA	"The gene pallbearer is referred to in FlyBase by the symbol Dmel\pall (CG3428, FBgn0036005). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:9486448..9487790. It has the cytological map location 67B10. Protein features are: F-box domain. Its molecular function is described by: ubiquitin-protein transferase activity. It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination. 9 alleles are reported. The phenotype of these alleles manifest in: macrophage. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0034935	Orcokinin	-0.395175206	0.268516062	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Orcokinin is referred to in FlyBase by the symbol Dmel\Orcokinin (CG13565, FBgn0034935). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2R:23946959..23949076. It has the cytological map location 60A13. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed in adult male stages.  "
FBgn0019938	RpI1	-0.394889322	0.299458297	0.999936032	POLR1A	POLR1A	high	NA	NA	NA	"The gene RNA polymerase I subunit is referred to in FlyBase by the symbol Dmel\RpI1 (CG10122, FBgn0019938). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:14595611..14601216. It has the cytological map location 51B4-51B6. Protein features are: DNA-directed RNA pol I, largest subunit; RNA polymerase Rpb1, domain 1; RNA polymerase Rpb1, domain 3; RNA polymerase Rpb1, domain 4; RNA polymerase Rpb1, domain 5; RNA polymerase, N-terminal; RNA polymerase, alpha subunit. Its molecular function is described by: DNA binding; zinc ion binding; RNA polymerase I activity. It is involved in the biological process described with: transcription, DNA-templated. 5 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; Z disc; sarcomere. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; partially lethal; lethal - all die during larval stage; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0053155	CG33155	-0.394748858	0.273622203	0.999936032	NA	MRPL53	low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG33155 (FBgn0053155). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:13954195..13955664. It has the cytological map location 50C16. Its molecular function is described by: . It is involved in the biological process described with: larval lymph gland hemopoiesis. 4 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval lymph gland. The phenotypic classes of alleles include: viable; lethal - all die during larval stage; lethal; lethal - all die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages, during late pupal stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0029672	CG2875	-0.394666028	0.307109517	0.999936032	NOC4L	NOC4L	high	Maybe TF(CBF)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG2875 (FBgn0029672). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:3571456..3573622. It has the cytological map location 3D6. Protein features are: Armadillo-like helical; CCAAT-binding factor; Nucleolar complex protein 4. Its molecular function is unknown. It is involved in the biological process described with: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). 9 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; ganglion mother cell; mesothoracic tergum. The phenotypic classes of alleles include: some die during pupal stage; partially lethal - majority die; neuroanatomy defective; viable; visible; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0003495	spz	-0.394511431	0.325972366	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene spatzle is referred to in FlyBase by the symbol Dmel\spz (CG6134, FBgn0003495). It is a protein_coding_gene from Drosophila melanogaster. It has 8 annotated transcripts and 8 polypeptides (all unique). Gene sequence location is 3R:27064990..27070070. It has the cytological map location 97E1. Protein features are: Cystine-knot cytokine; Spaetzle. Its molecular function is described by: morphogen activity; cytokine activity; growth factor activity; Toll binding; protein homodimerization activity. It is involved in the biological process described with 21 unique terms, many of which group under: chemotaxis; embryonic pattern specification; positive regulation of protein complex assembly; positive regulation of signaling; regulation of antifungal peptide biosynthetic process; cell maturation; protein complex assembly; larval somatic muscle development; cellular component morphogenesis; regulation of protein complex assembly. 55 alleles are reported. The phenotypes of these alleles manifest in: ventral furrow; embryonic/first instar larval cuticle; embryonic/larval somatic muscle; embryo; embryonic/larval fat body; embryonic/larval hemocoel. The phenotypic classes of alleles include: increased mortality; phenotype; increased mortality during development; locomotor behavior defective; lethal - all die before end of P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, during early pupal stages, in adult female stages.  "
FBgn0034628	Acox57D-p	-0.394098536	0.260548652	0.999936032	NA	ACOX1;ACOX2	moderate;moderate	NA	NA	NA	"The gene acyl-Coenzyme A oxidase at 57D proximal is referred to in FlyBase by the symbol Dmel\Acox57D-p (CG9707, FBgn0034628). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:21386309..21389276. It has the cytological map location 57E1. Protein features are: Acyl-CoA dehydrogenase/oxidase C-terminal; Acyl-CoA dehydrogenase/oxidase, N-terminal; Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain; Acyl-CoA oxidase; Acyl-CoA oxidase, C-terminal; Acyl-CoA oxidase/dehydrogenase, central domain; Acyl-coenzyme A oxidase, N-terminal. Its molecular function is described by: flavin adenine dinucleotide binding; FAD binding; acyl-CoA oxidase activity; acyl-CoA dehydrogenase activity. It is involved in the biological process described with: fatty acid beta-oxidation; fatty acid beta-oxidation using acyl-CoA dehydrogenase. 5 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0039483	CG14259	-0.394012773	0.282543537	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG14259 (FBgn0039483). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:27094533..27095856. It has the cytological map location 97E2. Protein features are: Haemolymph juvenile hormone binding. Its molecular function is described by: . It is involved in the biological process described with: multicellular organism reproduction; circadian rhythm. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed during late pupal stages.
FBgn0028473	Non1	-0.39378547	0.249709763	0.999936032	NA	GTPBP4	high	NA	NA	NA	"The gene Novel nucleolar protein 1 is referred to in FlyBase by the symbol Dmel\Non1 (CG8801, FBgn0028473). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:9396265..9398734. It has the cytological map location 45D1-45D3. Protein features are: GTP binding domain; NOG, C-terminal; Nucleolar GTP-binding protein 1; Nucleolar GTP-binding protein 1, Rossman-fold domain; OBG-type guanine nucleotide-binding (G) domain; P-loop containing nucleoside triphosphate hydrolase; Small GTP-binding protein domain. Its molecular function is described by: GTP binding. It is involved in the biological process described with: mitotic spindle assembly. 7 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0022986	qkr58E-1	-0.39341694	0.317955265	0.999936032	KHDRBS3	KHDRBS3;KHDRBS2;KHDRBS1;QKI	high;moderate;moderate;low	NA	NA	NA	"The gene quaking related 58E-1 is referred to in FlyBase by the symbol Dmel\qkr58E-1 (CG3613, FBgn0022986). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 2R:22412556..22415518. It has the cytological map location 58D8. Protein features are: K Homology domain; K Homology domain, type 1. Its molecular function is described by: RNA binding. It is involved in the biological process described with: mRNA splicing, via spliceosome. 10 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; embryonic/larval neuroblast; ganglion mother cell; mesothoracic tergum. The phenotypic classes of alleles include: increased mortality; stress response defective; some die during P-stage; viable; increased mortality during development; phenotype; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0011509	SrpRbeta	-0.393375421	0.258761066	0.999936032	NA	SRPRB	high	NA	transmembrane protein	NA	"The gene Signal recognition particle receptor ‘_ is referred to in FlyBase by the symbol Dmel\SrpR‘_ (CG33162, FBgn0011509). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:8718949..8720225. It has the cytological map location 66D11. Protein features are: P-loop containing nucleoside triphosphate hydrolase; Signal recognition particle receptor, beta subunit. Its molecular function is described by: signal recognition particle binding; GTPase activity. It is involved in the biological process described with: SRP-dependent cotranslational protein targeting to membrane; larval chitin-based cuticle development; chitin-based larval cuticle pattern formation. 7 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; embryonic/larval neuroblast. The phenotypic classes of alleles include: lethal; lethal - all die during P-stage; viable; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 06-18 hour embryonic stages, during early larval stages.  "
FBgn0066101	LpR1	-0.393349722	0.272129163	0.999936032	NA	VLDLR;LRP8;LDLR	high;moderate;moderate	NA	transmembrane protein	NA	"The gene Lipophorin receptor 1 is referred to in FlyBase by the symbol Dmel\LpR1 (CG31094, FBgn0066101). It is a protein_coding_gene from Drosophila melanogaster. It has 10 annotated transcripts and 10 polypeptides (9 unique). Gene sequence location is 3R:25741348..25763105. It has the cytological map location 96F1-96F2. Protein features are: EGF-like calcium-binding domain; EGF-like calcium-binding, conserved site; EGF-like domain; EGF-like, conserved site; EGF-type aspartate/asparagine hydroxylation site; Growth factor receptor cysteine-rich domain; LDLR class B repeat; Low-density lipoprotein (LDL) receptor class A repeat; Low-density lipoprotein (LDL) receptor class A, conserved site; Six-bladed beta-propeller, TolB-like. Its molecular function is described by: receptor activity; calcium ion binding. It is involved in the biological process described with: receptor-mediated endocytosis. 22 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: female fertile; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed in adult male stages.  "
FBgn0039209	REPTOR	-0.393258484	0.267685083	0.999936032	NA	CREBRF	high	DNA-binding with transcription factor activity(bZIP)	NA	NA	"The gene Repressed by TOR is referred to in FlyBase by the symbol Dmel\REPTOR (CG13624, FBgn0039209). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (2 unique). Gene sequence location is 3R:24557368..24582864. It has the cytological map location 96A7-96A9. Protein features are: Basic-leucine zipper domain. Its molecular function is described by: transcription factor activity, sequence-specific DNA binding; protein heterodimerization activity; protein homodimerization activity. It is involved in the biological process described with: positive regulation of transcription, DNA-templated; response to starvation; sleep; TORC1 signaling; regulation of multicellular organismal metabolic process. 28 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal; short lived; starvation stress response defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 12-24 hour embryonic stages.  "
FBgn0003896	tup	-0.392881622	0.349778098	0.999936032	NA	ISL1;ISL2	high;moderate	DNA-binding with transcription factor activity(Homeobox)	NA	NA	"The gene tailup is referred to in FlyBase by the symbol Dmel\tup (CG10619, FBgn0003896). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:18859507..18881261. It has the cytological map location 37B1. Protein features are: Homeobox domain; Homeobox domain-like; Homeobox, conserved site; Zinc finger, LIM-type. Its molecular function is described by: RNA polymerase II regulatory region sequence-specific DNA binding; RNA polymerase II activating transcription factor binding; RNA polymerase II distal enhancer sequence-specific DNA binding; protein binding; RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding; transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding. It is involved in the biological process described with 19 unique terms, many of which group under: tube development; muscle cell fate determination; regulation of sequence-specific DNA binding transcription factor activity; axis specification; positive regulation of biological process; muscle structure development; animal organ morphogenesis; regulation of biological quality; muscle cell fate commitment; embryonic axis specification; signaling; tissue morphogenesis; gland development. 26 alleles are reported. The phenotypes of these alleles manifest in: subesophageal ganglion; extended germ band embryo; adult antennal lobe projection neuron VA7m lPN; stage 7 embryo; A1-7 acute muscle; visceral muscle; antennal lobe glomerulus DM2; tegula; imaginal disc; mitotic domain 1. The phenotypic classes of alleles include: increased mortality; lethal - all die before end of first instar larval stage; viable; phenotype; partially lethal - majority live. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-18 hour embryonic stages.  "
FBgn0030336	CG1578	-0.392797463	0.297023547	0.999936032	DPH6	DPH6	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1578 (FBgn0030336). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is X:11808506..11816551. It has the cytological map location 10E5-10E6. Protein features are: Diphthamide synthase domain; Diphthine--ammonia ligase/Uncharacterised protein MJ0570; Endoribonuclease L-PSP/chorismate mutase-like; Rossmann-like alpha/beta/alpha sandwich fold; YjgF/YER057c/UK114 family. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0263594	lost	-0.392648637	0.251818909	0.999936032	NA	MTHFSD	high	NA	NA	NA	"The gene lost is referred to in FlyBase by the symbol Dmel\lost (CG14648, FBgn0263594). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:4403076..4407182. It has the cytological map location 82A6. Protein features are: 5-formyltetrahydrofolate cyclo-ligase; MTHFSD, RNA recognition motif. Its molecular function is unknown. It is involved in the biological process described with: pole plasm oskar mRNA localization; pole cell development; anterior/posterior pattern specification; mRNA splicing, via spliceosome; pole plasm mRNA localization. 21 alleles are reported. The phenotypes of these alleles manifest in: egg; larval abdominal segment. The phenotypic classes of alleles include: fertile; increased mortality; phenotype; increased mortality during development; viable; sterile; partially lethal - majority die; female fertile."
FBgn0038179	CG9312	-0.392603104	0.34632887	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG9312 (FBgn0038179). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:13765756..13767103. It has the cytological map location 87F13. Its molecular function is unknown. It is involved in the biological process described with: regulation of cell cycle. 2 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during early pupal stages.
FBgn0005593	RpL7	-0.392447027	0.249355526	0.999936032	NA	RPL7;RPL7L1	high;moderate	NA	NA	NA	"The gene Ribosomal protein L7 is referred to in FlyBase by the symbol Dmel\RpL7 (CG4897, FBgn0005593). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:10201004..10202321. It has the cytological map location 31B1. Protein features are: Ribosomal protein L30, N-terminal; Ribosomal protein L30, conserved site; Ribosomal protein L30, ferredoxin-like fold domain; Ribosomal protein L7, eukaryotic. Its molecular function is described by: structural constituent of ribosome; RNA binding. It is involved in the biological process described with: cytoplasmic translation; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); pupariation. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die during larval stage; developmental rate defective; lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages.  "
FBgn0259985	Mppe	-0.392430536	0.349891878	0.999936032	NA	MPPE1	moderate	NA	transmembrane protein	NA	"The gene Metallophosphoesterase is referred to in FlyBase by the symbol Dmel\Mppe (CG8889, FBgn0259985). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 2R:12025614..12027707. It has the cytological map location 48D7. Protein features are: Calcineurin-like phosphoesterase domain, ApaH type; Metallo-dependent phosphatase-like; PGAP5/Cdc1/Ted1. Its molecular function is described by: phosphatase activity. It is involved in the biological process described with: GPI anchor biosynthetic process; ER to Golgi vesicle-mediated transport; protein dephosphorylation. 14 alleles are reported. The phenotype of these alleles manifest in: rhabdomere. The phenotypic classes of alleles include: neurophysiology defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, during late pupal stages.  "
FBgn0030367	Cyp311a1	-0.392157717	0.292297535	0.999936032	NA	CYP4Z1;CYP4B1;CYP4X1;CYP4A11;CYP4A22;CYP19A1;CYP26B1;CYP4V2;CYP4F3;CYP4F2;CYP4F11;CYP4F22;CYP4F12	high;high;high;low;low;moderate;moderate;low;low;low;low;moderate;low	NA	NA	NA	"The gene Cyp311a1 is referred to in FlyBase by the symbol Dmel\Cyp311a1 (CG1488, FBgn0030367). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:12029754..12031465. It has the cytological map location 11A2. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Its molecular function is described by: heme binding; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. It is involved in the biological process described with: oxidation-reduction process. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable; lethal - all die during P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed at stages throughout the larval period, during late pupal stages, in adult male stages.  "
FBgn0029909	mAChR-C	-0.391864222	0.34494223	0.999936032	NA	GPR119	high	NA	transmembrane protein	GPCR	"The gene muscarinic Acetylcholine Receptor, C-type is referred to in FlyBase by the symbol Dmel\mAChR-C (CG12796, FBgn0029909). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:6831397..6832684. It has the cytological map location 6D4. Protein features are: G protein-coupled receptor, rhodopsin-like; GPCR, rhodopsin-like, 7TM. Its molecular function is described by: G-protein coupled amine receptor activity; dopamine neurotransmitter receptor activity, coupled via Gs; G-protein coupled acetylcholine receptor activity. It is involved in the biological process described with: G-protein coupled acetylcholine receptor signaling pathway; G-protein coupled receptor signaling pathway. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: pain response defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very low expression to a trough of extremely low expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0261597	RpS26	-0.391370988	0.251475526	0.999936032	NA	RPS26;LOC101929876;RPS26P11	high;moderate;moderate	NA	NA	NA	"The gene Ribosomal protein S26 is referred to in FlyBase by the symbol Dmel\RpS26 (CG10305, FBgn0261597). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is 2L:18441335..18443277. It has the cytological map location 36F4-36F6. Protein features are: Ribosomal protein S26e. Its molecular function is described by: structural constituent of ribosome; mRNA binding. It is involved in the biological process described with: cytoplasmic translation; translation. 12 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: small body; partially lethal; lethal; Minute; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0028965	A16	-0.391356965	0.308876965	0.999936032	NA	NA	NA	NA	NA	NA	"The gene A16 is referred to in FlyBase by the symbol Dmel\A16 (CG9933, FBgn0028965). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:13019575..13021312. It has the cytological map location 34A4. Protein features are: Chromo/chromo shadow domain. Its molecular function is described by: protein phosphatase 1 binding. It is involved in the biological process described with: . 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0010520	Bka	-0.391209265	0.274559772	0.999936032	NA	FCF1	high	Chromatin regulation	NA	NA	"The gene Bekka is referred to in FlyBase by the symbol Dmel\Bka (CG4539, FBgn0010520). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:9895287..9896104. It has the cytological map location 30E1. Protein features are: PIN domain; PIN domain-like; rRNA-processing protein Fcf1/Utp23. Its molecular function is unknown. It is involved in the biological process described with: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); neuron projection morphogenesis; cellular response to starvation. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; short lived; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0004867	RpS2	-0.390986856	0.250014538	0.999936032	NA	RPS2	high	NA	NA	NA	"The gene Ribosomal protein S2 is referred to in FlyBase by the symbol Dmel\RpS2 (CG5920, FBgn0004867). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:9896265..9897552. It has the cytological map location 30E1. Protein features are: Ribosomal protein S5; Ribosomal protein S5 domain 2-type fold; Ribosomal protein S5 domain 2-type fold, subgroup; Ribosomal protein S5, C-terminal; Ribosomal protein S5, N-terminal; Ribosomal protein S5, N-terminal, conserved site; Ribosomal protein S5, eukaryotic/archaeal. Its molecular function is described by: RNA binding; structural constituent of ribosome. It is involved in the biological process described with: translation; cytoplasmic translation. 23 alleles are reported. The phenotypes of these alleles manifest in: cytoplasm; non-membrane-bounded organelle; cell; macrochaeta; cell; anatomical group; intracellular part; portion of tissue; Z disc; sensory system. The phenotypic classes of alleles include: some die during larval stage; increased mortality; lethal - all die before end of larval stage; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0036249	CG11560	-0.390535866	0.324605414	0.999936032	NA	MSANTD1	low	DNA-binding with transcription factor activity(zf-BED)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11560 (FBgn0036249). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:12120019..12121185. It has the cytological map location 68F4. Protein features are: Myb/SANT-like DNA-binding domain-containing protein; Zinc finger, BED-type. Its molecular function is described by: DNA binding. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0037250	CG1074	-0.390286611	0.290955677	0.999936032	NA	TRMT11	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1074 (FBgn0037250). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:4433965..4436175. It has the cytological map location 82B1. Protein features are: DNA methylase, N-6 adenine-specific, conserved site; Putative RNA methylase domain; S-adenosyl-L-methionine-dependent methyltransferase; tRNA guanosine-2'-O-methyltransferase, TRM11. Its molecular function is described by: methyltransferase activity; nucleic acid binding. It is involved in the biological process described with: methylation. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed during early larval stages.  "
FBgn0000406	Cyt-b5-r	-0.389487635	0.293912826	0.999936032	NA	FADS1;FADS2;FADS3	high;high;high	NA	transmembrane protein	NA	"The gene Cytochrome b5-related is referred to in FlyBase by the symbol Dmel\Cyt-b5-r (CG13279, FBgn0000406). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:16788774..16790721. It has the cytological map location 36B1. Protein features are: Cytochrome b5, heme-binding site; Cytochrome b5-like heme/steroid binding domain; Fatty acid desaturase; Fatty acid desaturase domain. Its molecular function is described by: heme binding; oxidoreductase activity. It is involved in the biological process described with: lipid metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0016685	Nlp	-0.389066063	0.26238044	0.999936032	NA	NPM3;NPM2;NPM1	high;moderate;moderate	NA	NA	NA	"The gene Nucleoplasmin is referred to in FlyBase by the symbol Dmel\Nlp (CG7917, FBgn0016685). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:30004785..30010352. It has the cytological map location 99D1. Protein features are: Nucleoplasmin core domain; Nucleoplasmin family. Its molecular function is described by: histone binding. It is involved in the biological process described with: sperm chromatin decondensation; chromatin remodeling. 8 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in adult female stages.  "
FBgn0039828	CG1542	-0.388901921	0.290242666	0.999936032	EBNA1BP2	EBNA1BP2;MIR6733	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1542 (FBgn0039828). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:31213458..31214784. It has the cytological map location 100B6-100B7. Protein features are: Eukaryotic rRNA processing. Its molecular function is described by: RNA binding. It is involved in the biological process described with: ribosomal large subunit biogenesis; rRNA processing. 3 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; Z disc; sarcomere. The phenotypic classes of alleles include: lethal - all die during larval stage; lethal; visible; partially lethal - majority die; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0032818	CG10628	-0.388766187	0.321488272	0.999936032	GTPBP10	GTPBP10;LOC101927446	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10628 (FBgn0032818). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:19757245..19758615. It has the cytological map location 38A2. Protein features are: GTP binding domain; GTP-binding protein, Obg-type; GTP1/OBG domain; OBG-type guanine nucleotide-binding (G) domain; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: GTP binding. It is involved in the biological process described with: . 5 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: viable; visible; some die during pupal stage; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0036686	CG7728	-0.388711252	0.326988191	0.999936032	BMS1	BMS1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7728 (FBgn0036686). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:17016536..17020270. It has the cytological map location 73E4. Protein features are: AARP2CN; Bms1/Tsr1-type G domain; P-loop containing nucleoside triphosphate hydrolase; Ribosome biogenesis protein BMS1/TSR1, C-terminal. Its molecular function is described by: GTP binding; U3 snoRNA binding; GTPase activity. It is involved in the biological process described with: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); cellular response to starvation. 3 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; ganglion mother cell; embryonic/larval neuroblast. The phenotypic classes of alleles include: increased mortality during development; phenotype; lethal; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0035082	CG2811	-0.388441696	0.265055343	0.999936032	NA	GGACT	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG2811 (FBgn0035082). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 2R:24939706..24940483. It has the cytological map location 60E5. Protein features are: Gamma-glutamyl cyclotransferase-like; Gamma-glutamylcyclotransferase, AIG2-like. Its molecular function is described by: . It is involved in the biological process described with: . 11 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages.  "
FBgn0027779	VhaSFD	-0.388335245	0.255136498	0.999936032	ATP6V1H	ATP6V1H	high	NA	NA	NA	"The gene Vacuolar H<sup>+</sup>-ATPase SFD subunit is referred to in FlyBase by the symbol Dmel\VhaSFD (CG17332, FBgn0027779). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 2L:16722883..16727826. It has the cytological map location 36A12. Protein features are: ATPase, V1 complex, subunit H; ATPase, V1 complex, subunit H, C-terminal; Armadillo-like helical; Armadillo-type fold. Its molecular function is described by: proton-transporting ATPase activity, rotational mechanism. It is involved in the biological process described with: dsRNA transport; vacuolar acidification; ATP hydrolysis coupled proton transport; determination of adult lifespan. 9 alleles are reported. The phenotypes of these alleles manifest in: eye disc; multivesicular body; Malpighian tubule; embryonic/larval somatic muscle. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; increased mortality during development; phenotype; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0002719	Men	-0.388327825	0.261699706	0.999936032	NA	ME1;ME2;ME3	high;moderate;moderate	NA	NA	NA	"The gene Malic enzyme is referred to in FlyBase by the symbol Dmel\Men (CG10120, FBgn0002719). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3R:12713103..12722442. It has the cytological map location 87C6-87C7. Protein features are: Malic enzyme, N-terminal domain; Malic enzyme, NAD-binding; Malic enzyme, conserved site; Malic oxidoreductase; NAD(P)-binding domain. Its molecular function is described by: NAD binding; malate dehydrogenase (decarboxylating) (NADP+) activity; malate dehydrogenase (decarboxylating) (NAD+) activity. It is involved in the biological process described with: oxidation-reduction process; determination of adult lifespan; malate metabolic process; sleep; regulation of cell death; pyruvate metabolic process. 93 alleles are reported. The phenotypes of these alleles manifest in: germline cell; eye. The phenotypic classes of alleles include: electrophoretic variant; fertile; stress response defective; phenotype; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.  "
FBgn0002590	RpS5a	-0.388154077	0.254083195	0.999936032	RPS5	RPS5	high	NA	NA	NA	"The gene Ribosomal protein S5a is referred to in FlyBase by the symbol Dmel\RpS5a (CG8922, FBgn0002590). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is X:17143588..17148264. It has the cytological map location 15E5-15E7. Protein features are: Ribosomal protein S5/S7; Ribosomal protein S5/S7, eukaryotic/archaeal; Ribosomal protein S7 domain; Ribosomal protein S7, conserved site. Its molecular function is described by: rRNA binding; structural constituent of ribosome; mRNA binding. It is involved in the biological process described with: translation; ribosomal small subunit assembly; cytoplasmic translation. 16 alleles are reported. The phenotypes of these alleles manifest in: sarcomere; macrochaeta; Z disc; adult heart. The phenotypic classes of alleles include: increased mortality during development; phenotype; lethal; developmental rate defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in adult female stages.  "
FBgn0259704	Nsun5	-0.388081306	0.295052451	0.999936032	NA	NSUN5;NSUN5P2;NSUN5P1;NSUN7	high;moderate;moderate;low	NA	NA	NA	"The gene Nop2/Sun-like domain containing protein 5 is referred to in FlyBase by the symbol Dmel\Nsun5 (CG42358, FBgn0259704). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:19160099..19162300. It has the cytological map location 91F4. Protein features are: RNA (C5-cytosine) methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase; SAM-dependent methyltransferase RsmB/NOP2-type. Its molecular function is described by: S-adenosylmethionine-dependent methyltransferase activity; RNA methyltransferase activity. It is involved in the biological process described with: rRNA base methylation; positive regulation of innate immune response; defense response to Gram-negative bacterium. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; short lived; long lived; heat stress response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0028331	l(1)G0289	-0.387975628	0.261370513	0.999936032	NA	PLXDC2;PLXDC1	high;moderate	NA	transmembrane protein	NA	"The gene lethal (1) G0289 is referred to in FlyBase by the symbol Dmel\l(1)G0289 (CG2221, FBgn0028331). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is X:10348680..10366273. It has the cytological map location 9B7-9B12. Protein features are: Plexin domain-containing protein; Plexin repeat. Its molecular function is unknown. The biological processes in which it is involved are not known. 18 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: long lived; some die during P-stage; lethal; increased mortality; body color defective; lethal - all die during P-stage; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed within 00-06 and 12-18 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.  "
FBgn0267376	SelR	-0.387898301	0.280095019	0.999936032	NA	MSRB3;MSRB2;MSRB1	high;moderate;moderate	NA	NA	NA	"The gene Selenoprotein R is referred to in FlyBase by the symbol Dmel\SelR (CG6584, FBgn0267376). It is a protein_coding_gene from Drosophila melanogaster. It has 8 annotated transcripts and 8 polypeptides (7 unique). Gene sequence location is 3R:10863355..10868642. It has the cytological map location 86C7. Protein features are: Mss4-like; Peptide methionine sulfoxide reductase; Peptide methionine sulphoxide reductase MrsB. Its molecular function is described by: peptide-methionine (R)-S-oxide reductase activity; zinc ion binding. It is involved in the biological process described with: chaeta morphogenesis; actin filament polymerization; response to oxidative stress; oxidation-reduction process; skeletal muscle thin filament assembly; protein repair; actin filament organization; axon guidance. 13 alleles are reported. The phenotypes of these alleles manifest in: macrochaeta; synapse; embryonic/larval somatic muscle; intersegmental nerve branch ISNb of A1-7; intersegmental nerve; filamentous actin. The phenotypic class of alleles includes: neuroanatomy defective."
FBgn0038400	CG5903	-0.387843518	0.258049922	0.999936032	NA	APOOL;APOO	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5903 (FBgn0038400). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:16144401..16146855. It has the cytological map location 89B6. Protein features are: MICOS complex subunit MIC26/MIC27; MICOS complex subunit MIC26/MIC27, animal. Its molecular function is unknown. It is involved in the biological process described with: cristae formation. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0037683	CG18473	-0.387788505	0.352801682	0.999936032	NA	PTER	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG18473 (FBgn0037683). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:9363305..9364838. It has the cytological map location 85D11-85D12. Protein features are: Aryldialkylphosphatase, zinc-binding site; Metal-dependent hydrolase; Phosphotriesterase. Its molecular function is described by: zinc ion binding; hydrolase activity, acting on ester bonds. It is involved in the biological process described with: catabolic process. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during late larval stages.  "
FBgn0010412	RpS19a	-0.387772467	0.258932394	0.999936032	NA	RPS19	high	NA	NA	NA	"The gene Ribosomal protein S19a is referred to in FlyBase by the symbol Dmel\RpS19a (CG4464, FBgn0010412). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is X:16637894..16639249. It has the cytological map location 14F4. Protein features are: Ribosomal protein S19e; Ribosomal protein S19e, conserved site; Winged helix-turn-helix DNA-binding domain. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; translation; ribosomal small subunit assembly. 5 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, in adult female stages.  "
FBgn0039325	CG10560	-0.387522383	0.299040927	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10560 (FBgn0039325). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:25318550..25320101. It has the cytological map location 96D1. Protein features are: CHK kinase-like; Protein kinase-like domain; Protein of unknown function DUF227. Its molecular function is described by: . It is involved in the biological process described with: . 5 alleles are reported. The phenotypes of these alleles manifest in: M band; myofibril; sarcomere. The phenotypic classes of alleles include: flightless; fertile; lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, in adult male stages.  "
FBgn0039113	CG10217	-0.387213059	0.356834814	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG10217 (FBgn0039113). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:23760737..23763263. It has the cytological map location 95B1. Its molecular function is described by: . It is involved in the biological process described with: wound healing. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages.
FBgn0042086	Tsp42Eb	-0.386563846	0.256019522	0.999936032	NA	CD63	low	NA	transmembrane protein	NA	"The gene Tetraspanin 42Eb is referred to in FlyBase by the symbol Dmel\Tsp42Eb (CG18816, FBgn0042086). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:6998848..6999848. It has the cytological map location 42E4. Protein features are: Tetraspanin; Tetraspanin, EC2 domain; Tetraspanin/Peripherin. Its molecular function is described by: . It is involved in the biological process described with: . One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed in adult male stages.  "
FBgn0017566	ND-75	-0.386285485	0.261904004	0.999936032	NA	NDUFS1	high	NA	NA	NA	"The gene NADH dehydrogenase (ubiquinone) 75 kDa subunit is referred to in FlyBase by the symbol Dmel\ND-75 (CG2286, FBgn0017566). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:8248651..8251687. It has the cytological map location 7E1. Protein features are: 2Fe-2S ferredoxin-type iron-sulfur binding domain; Beta-grasp domain; DHS-like NAD/FAD-binding domain; Molybdopterin oxidoreductase; Molybdopterin oxidoreductase, 4Fe-4S domain; NADH-quinone oxidoreductase, chain G, C-terminal; NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site; NADH:ubiquinone oxidoreductase, subunit G; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding. Its molecular function is described by: NADH dehydrogenase (ubiquinone) activity; NADH dehydrogenase activity; electron carrier activity; iron-sulfur cluster binding. It is involved in the biological process described with: apoptotic mitochondrial changes; ATP synthesis coupled electron transport; reactive oxygen species metabolic process; cellular respiration. 7 alleles are reported. The phenotypes of these alleles manifest in: lamellocyte; adult brain; wing disc dorsal compartment; mitochondrion; autophagosome. The phenotypic classes of alleles include: cell number defective; cell death defective; phenotype; stress response defective; increased cell number. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0003885	alphaTub84D	-0.385858244	0.276486925	0.999936032	TUBA1C	TUBA3D;TUBA3E;TUBA3C;TUBA1C;TUBA1A;TUBA1B;TUBA8;TUBA4A;TUBAL3	moderate;moderate;moderate;moderate;moderate;moderate;moderate;low;low	NA	NA	NA	"The gene ‘±-Tubulin at 84D is referred to in FlyBase by the symbol Dmel\‘±Tub84D (CG2512, FBgn0003885). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:7530753..7532732. It has the cytological map location 84D9. Protein features are: Alpha tubulin; Tubulin; Tubulin, conserved site; Tubulin/FtsZ, 2-layer sandwich domain; Tubulin/FtsZ, C-terminal; Tubulin/FtsZ, GTPase domain. Its molecular function is described by: myosin binding; GTPase activity; structural constituent of cytoskeleton; GTP binding. It is involved in the biological process described with: mitotic cytokinesis; microtubule-based process. 9 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-12 hour embryonic stages, in adult male stages.  "
FBgn0002622	RpS3	-0.385746191	0.257703263	0.999936032	NA	RPS3	high	NA	NA	NA	"The gene Ribosomal protein S3 is referred to in FlyBase by the symbol Dmel\RpS3 (CG6779, FBgn0002622). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:23358812..23360207. It has the cytological map location 94E13. Protein features are: K Homology domain, type 2; K homology domain, prokaryotic type; K homology domain-like, alpha/beta; Ribosomal protein S3, C-terminal; Ribosomal protein S3, conserved site; Ribosomal protein S3, eukaryotic/archaeal. Its molecular function is described by: damaged DNA binding; structural constituent of ribosome; RNA binding; DNA-(apurinic or apyrimidinic site) lyase activity; oxidized purine DNA binding; oxidized purine nucleobase lesion DNA N-glycosylase activity. It is involved in the biological process described with: DNA repair; cytoplasmic translation; negative regulation of neuron apoptotic process; translation; cellular response to DNA damage stimulus; mitotic cell cycle. 16 alleles are reported. The phenotypes of these alleles manifest in: spermatocyte cyst; cell; adult thoracic segment; developing material anatomical entity; circulatory system; eye-antennal disc; eye; adult heart; testis; embryonic/larval imaginal precursor; adult external mesothorax; ovariole. The phenotypic classes of alleles include: phenotype; visible; developmental rate defective; fertile; sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages.  "
FBgn0033379	Mys45A	-0.385502456	0.289587765	0.999936032	NA	SDAD1	high	NA	NA	NA	"The gene Mystery 45A is referred to in FlyBase by the symbol Dmel\Mys45A (CG8070, FBgn0033379). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:9111505..9113951. It has the cytological map location 45A7-45A8. Protein features are: Armadillo-like helical; Armadillo-type fold; SDA1 domain; Sda1; Uncharacterised domain NUC130/133, N-terminal. Its molecular function is unknown. It is involved in the biological process described with: actin cytoskeleton organization; ribosomal large subunit export from nucleus; ribosomal large subunit biogenesis. 6 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; ganglion mother cell; embryonic/larval neuroblast. The phenotypic classes of alleles include: visible; short lived; lethal; partially lethal; partially lethal - majority die; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0031540	Pif1	-0.385384757	0.355832755	0.999936032	NA	PIF1	high	NA	NA	NA	"The gene Pif1 ortholog is referred to in FlyBase by the symbol Dmel\Pif1 (CG3238, FBgn0031540). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:3467342..3470004. It has the cytological map location 23F3. Protein features are: DNA helicase; DNA helicase Pif1-like; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: telomerase inhibitor activity; ATP-dependent 5'-3' DNA helicase activity; ATP binding. It is involved in the biological process described with: G-quadruplex DNA unwinding; negative regulation of telomere maintenance via telomerase; DNA duplex unwinding; negative regulation of telomerase activity; mitochondrial genome maintenance; DNA repair; DNA replication. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; flight defective; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0051217	modSP	-0.385219917	0.358487869	0.999936032	NA	LRP10;LRP3;LRP12;ST14;TMPRSS6;C1R;SEZ6;TMPRSS7;SEZ6L2;TMPRSS15;SEZ6L;F10;TMPRSS3;CSMD2;PROC;C1RL;OVCH1;C1S;PAMR1;MASP1;MASP2	low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low	NA	NA	NA	"The gene modular serine protease is referred to in FlyBase by the symbol Dmel\modSP (CG31217, FBgn0051217). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:16652446..16655662. It has the cytological map location 89D6. Protein features are: Low-density lipoprotein (LDL) receptor class A repeat; Low-density lipoprotein (LDL) receptor class A, conserved site; Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Sushi/SCR/CCP domain. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; regulation of Toll signaling pathway; innate immune response; defense response to Gram-positive bacterium. 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; lethal; viable; lethal - all die during embryonic stage; immune response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed during early pupal stages.  "
FBgn0034986	mRpS17	-0.385099354	0.279491975	0.999936032	NA	MRPS17	high	NA	NA	NA	"The gene mitochondrial ribosomal protein S17 is referred to in FlyBase by the symbol Dmel\mRpS17 (CG4326, FBgn0034986). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:24173665..24174441. It has the cytological map location 60C1. Protein features are: Nucleic acid-binding, OB-fold; Ribosomal protein S17/S11. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages, during late pupal stages.  "
FBgn0005536	Mbs	-0.384880938	0.284187821	0.999936032	NA	PPP1R12B;PPP1R12A;PPP1R12C;PPP1R27	high;moderate;moderate;moderate	NA	NA	NA	"The gene Myosin binding subunit is referred to in FlyBase by the symbol Dmel\Mbs (CG32156, FBgn0005536). It is a protein_coding_gene from Drosophila melanogaster. It has 13 annotated transcripts and 13 polypeptides (all unique). Gene sequence location is 3L:16051959..16082026. It has the cytological map location 72D1. Protein features are: Ankyrin repeat; Ankyrin repeat-containing domain; cGMP-dependent protein kinase, interacting domain. Its molecular function is described by: protein kinase binding. It is involved in the biological process described with: imaginal disc-derived wing hair organization; epidermis development; oogenesis; neuron projection morphogenesis; axon extension; dorsal closure; germline ring canal formation; imaginal disc morphogenesis; regulation of locomotor rhythm; regulation of compound eye photoreceptor development. 46 alleles are reported. The phenotypes of these alleles manifest in: pupa; alimentary canal; cytoplasm; pacemaker neuron; portion of tissue; egg; epithelial furrow; anterior embryonic/larval midgut; neuron projection; larval mesothoracic segment; non-membrane-bounded organelle. The phenotypic classes of alleles include: cell polarity defective; female semi-sterile; phenotype; increased mortality during development; circadian rhythm defective; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0260456	CG4806	-0.384694577	0.310041515	0.999936032	NA	RBM28	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4806 (FBgn0260456). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:24666158..24668343. It has the cytological map location 60D13. Protein features are: RNA recognition motif domain. Its molecular function is described by: mRNA binding; nucleic acid binding. The biological processes in which it is involved are not known. 7 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; ganglion mother cell; embryonic/larval neuroblast; trichogen cell. The phenotypic classes of alleles include: neuroanatomy defective; pain response defective; lethal; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0035006	CG4563	-0.384544311	0.291051027	0.999936032	NA	ACSBG1;FADD;ACSF3	low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4563 (FBgn0035006). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:24451084..24453040. It has the cytological map location 60D1. Protein features are: AMP-binding enzyme, C-terminal domain; AMP-dependent synthetase/ligase. Its molecular function is described by: catalytic activity. It is involved in the biological process described with: metabolic process. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0037163	laza	-0.384138701	0.298886969	0.999936032	NA	PLPP1;PLPP3;PLPP2;PLPP5;PLPPR2;PLPP4	moderate;moderate;moderate;low;moderate;low	NA	transmembrane protein	NA	"The gene lazaro is referred to in FlyBase by the symbol Dmel\laza (CG11440, FBgn0037163). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:22458816..22461131. It has the cytological map location 79E4. Protein features are: Phosphatidic acid phosphatase type 2/haloperoxidase. Its molecular function is described by: lipid phosphatase activity; phosphatidate phosphatase activity. It is involved in the biological process described with: phototransduction; phospholipid metabolic process; phospholipid dephosphorylation; dephosphorylation; thermotaxis; response to light intensity. 13 alleles are reported. The phenotypes of these alleles manifest in: eye; rhabdomere. The phenotypic classes of alleles include: neurophysiology defective; thermotaxis behavior defective; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0264302	CG43780	-0.383896182	0.350063964	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG43780 (FBgn0264302). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:7333544..7335226. It has the cytological map location 65F5. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable.
FBgn0264303	CG43781	-0.383896182	0.350063964	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG43781 (FBgn0264303). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:7333544..7335226. It has the cytological map location 65F5. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile.
FBgn0032729	L2HGDH	-0.383861293	0.301036557	0.999936032	NA	L2HGDH	high	NA	NA	NA	"The gene L-2-hydroxyglutarate dehydrogenase is referred to in FlyBase by the symbol Dmel\L2HGDH (CG10639, FBgn0032729). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:18971993..18974448. It has the cytological map location 37B8. Protein features are: FAD dependent oxidoreductase; FAD/NAD(P)-binding domain. Its molecular function is described by: oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; short lived; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0027580	PCB	-0.383516751	0.273550793	0.999936032	NA	PC	high	NA	NA	NA	"The gene Pyruvate carboxylase is referred to in FlyBase by the symbol Dmel\PCB (CG1516, FBgn0027580). It is a protein_coding_gene from Drosophila melanogaster. It has 10 annotated transcripts and 10 polypeptides (2 unique). Gene sequence location is 2R:9850703..9861543. It has the cytological map location 46B4-46C1. Protein features are: ATP-grasp fold; ATP-grasp fold, subdomain 1; Aldolase-type TIM barrel; Biotin carboxylase, C-terminal; Biotin carboxylase-like, N-terminal domain; Biotin carboxylation domain; Biotin-binding site; Biotin/lipoyl attachment; Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain; Carboxylase, conserved domain; Pre-ATP-grasp domain; Pyruvate carboxylase; Pyruvate carboxyltransferase; Rudiment single hybrid motif; Single hybrid motif. Its molecular function is described by: ATP binding; pyruvate carboxylase activity; biotin binding; metal ion binding; biotin carboxylase activity. It is involved in the biological process described with: pyruvate metabolic process; gluconeogenesis. 20 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; memory defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed during early larval stages, during late pupal stages.  "
FBgn0039941	CG17167	-0.383443227	0.282378023	0.999936032	NA	SLC24A5;SLC24A3;SLC24A4	moderate;moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17167 (FBgn0039941). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is X:23068301..23081144. Protein features are: Sodium/calcium exchanger membrane region; Sodium/potassium/calcium exchanger. Its molecular function is described by: potassium ion binding; sodium ion binding; calcium channel activity; calcium, potassium:sodium antiporter activity; calcium ion binding. It is involved in the biological process described with: cellular calcium ion homeostasis; transmembrane transport. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0034817	Art7	-0.383428494	0.321223155	0.999936032	PRMT7	PRMT7	high	NA	NA	NA	"The gene Arginine methyltransferase 7 is referred to in FlyBase by the symbol Dmel\Art7 (CG9882, FBgn0034817). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:23076688..23079038. It has the cytological map location 59C3. Protein features are: Protein arginine N-methyltransferase; Protein arginine N-methyltransferase PRMT7; S-adenosyl-L-methionine-dependent methyltransferase. Its molecular function is described by: protein-arginine omega-N symmetric methyltransferase activity; histone-arginine N-methyltransferase activity; protein-arginine omega-N monomethyltransferase activity; protein-arginine N-methyltransferase activity; protein-arginine omega-N asymmetric methyltransferase activity. It is involved in the biological process described with: peptidyl-arginine methylation; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine; regulation of transcription, DNA-templated. 4 alleles are reported. The phenotypes of these alleles manifest in: myofibril; sarcomere; M band. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; some die during pupal stage; viable; flightless. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed in adult female stages.  "
FBgn0261593	RpS10b	-0.383015722	0.260959719	0.999936032	NA	RPS10;RPS10-NUDT3;RPS10P5	high;moderate;moderate	NA	NA	NA	NA
FBgn0267605	CR45943	-0.38295281	0.329802186	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45943 (FBgn0267605). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3L:20838313..20838700. It has the cytological map location 77F1. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0031875	CG3430	-0.38276831	0.360067749	0.999936032	MCMBP	MCMBP	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG3430 (FBgn0031875). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:6957008..6959104. It has the cytological map location 27C7. Protein features are: Mini-chromosome maintenance complex-binding protein. Its molecular function is described by: chromatin binding. It is involved in the biological process described with: DNA-dependent DNA replication; sister chromatid cohesion. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0004892	sob	-0.382667895	0.356943095	0.999936032	NA	OSR2;OSR1	high;moderate	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene sister of odd and bowl is referred to in FlyBase by the symbol Dmel\sob (CG3242, FBgn0004892). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:3578013..3580769. It has the cytological map location 24A1. Protein features are: Zinc finger C2H2-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: RNA polymerase II transcription factor activity, sequence-specific DNA binding; nucleic acid binding. It is involved in the biological process described with: phagocytosis; periodic partitioning by pair rule gene; positive regulation of transcription, DNA-templated; blastoderm segmentation; imaginal disc-derived leg joint morphogenesis; regulation of transcription, DNA-templated; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-templated; positive regulation of transcription from RNA polymerase II promoter. 7 alleles are reported. The phenotypes of these alleles manifest in: sex comb; tarsal segment; wing; ventral thoracic disc. The phenotypic class of alleles includes: visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0034999	CG3394	-0.382656867	0.2722726	0.999936032	NA	SLC27A4;SLC27A1;SLC27A6;SLC27A3;SLC27A2;SLC27A5	moderate;moderate;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3394 (FBgn0034999). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:24294097..24298111. It has the cytological map location 60C6. Protein features are: AMP-binding enzyme, C-terminal domain; AMP-binding, conserved site; AMP-dependent synthetase/ligase; Fatty acid transport protein 4. Its molecular function is described by: very long-chain fatty acid-CoA ligase activity; long-chain fatty acid-CoA ligase activity. It is involved in the biological process described with: fatty acid transport; metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late larval stages.  "
FBgn0038473	Ns1	-0.3824284	0.291540109	0.999936032	NA	GNL3L;GNL3	high;moderate	NA	NA	NA	"The gene Nucleostemin 1 is referred to in FlyBase by the symbol Dmel\Ns1 (CG3983, FBgn0038473). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:17070523..17072675. It has the cytological map location 89E11. Protein features are: Circularly permuted (CP)-type guanine nucleotide-binding (G) domain; GTP binding domain; GTP-binding protein, orthogonal bundle domain; Guanine nucleotide-binding protein-like 3, N-terminal domain; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: GTP binding; ATPase activity; GTPase activity. It is involved in the biological process described with: regulation of insulin receptor signaling pathway; cellular response to starvation; regulation of multicellular organism growth; ribosomal large subunit biogenesis; mitotic spindle assembly; regulation of cell proliferation; positive regulation of multicellular organism growth. 9 alleles are reported. The phenotypes of these alleles manifest in: contractile fiber part; compound sense organ; melanotic mass; pupa; procephalic segment; membrane-enclosed lumen; circulatory system; eye; supramolecular polymer; non-membrane-bounded organelle; thorax. The phenotypic classes of alleles include: majority die during larval stage; phenotype; visible; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, during early larval stages.  "
FBgn0050035	Tret1-1	-0.382411215	0.299934661	0.999936032	NA	SLC2A6;SLC2A8;SLC2A13;SLC2A10	high;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene Trehalose transporter 1-1 is referred to in FlyBase by the symbol Dmel\Tret1-1 (CG30035, FBgn0050035). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:11665768..11674782. It has the cytological map location 48B6-48B7. Protein features are: Major facilitator superfamily domain; Major facilitator,  sugar transporter-like; Sugar transporter, conserved site; Sugar/inositol transporter. Its molecular function is described by: trehalose transmembrane transporter activity; sugar:proton symporter activity; glucose transmembrane transporter activity. It is involved in the biological process described with: trehalose transport; hexose transmembrane transport; glucose import. 15 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; flightless; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late pupal stages.  "
FBgn0032297	CG17124	-0.382169877	0.334864091	0.999936032	NA	PPP1R14B;PPP1R14C;PPP1R14A;PPP1R14D	high;moderate;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17124 (FBgn0032297). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:10744075..10756325. It has the cytological map location 32A5. Protein features are: PKC-activated phosphatase-1 inhibitor. Its molecular function is unknown. It is involved in the biological process described with: regulation of phosphorylation. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages, during early pupal stages.  "
FBgn0005585	Calr	-0.381940604	0.261474108	0.999936032	NA	CALR;CALR3	high;moderate	NA	NA	NA	"The gene Calreticulin is referred to in FlyBase by the symbol Dmel\Calr (CG9429, FBgn0005585). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:9628691..9630851. It has the cytological map location 85E1. Protein features are: Calreticulin; Calreticulin/calnexin; Calreticulin/calnexin, P domain; Calreticulin/calnexin, conserved site; Concanavalin A-like lectin/glucanase domain. Its molecular function is described by: unfolded protein binding; calcium ion binding. It is involved in the biological process described with: olfactory behavior; central nervous system development; sleep; peripheral nervous system development; protein folding. 40 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; embryonic/larval neuroblast; presumptive embryonic/larval peripheral nervous system; neuron; macrochaeta. The phenotypic classes of alleles include: sleep defective; chemical resistant; chemical sensitive; fertile; increased mortality; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed within 06-18 hour embryonic stages.  "
FBgn0036428	Gbs-70E	-0.381691764	0.30696573	0.999936032	NA	PPP1R3C;PPP1R3B;PPP1R3E;PPP1R3D;PPP1R3G	high;moderate;low;low;moderate	NA	NA	NA	"The gene Glycogen binding subunit 70E is referred to in FlyBase by the symbol Dmel\Gbs-70E (CG9238, FBgn0036428). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:14540937..14550975. It has the cytological map location 70E1-70E2. Protein features are: CBM21 (carbohydrate binding type-21) domain; Immunoglobulin-like fold; Protein phosphatase 1 regulatory subunit 3B/C/D, metazoa. Its molecular function is described by: protein phosphatase 1 binding; glycogen binding. It is involved in the biological process described with: regulation of glycogen metabolic process; behavioral response to ethanol. 14 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; female semi-sterile; short lived; chemical resistant; hyperactive. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, in adult female stages.  "
FBgn0033980	Cyp6a20	-0.381251452	0.277627159	0.999936032	TBXAS1	TBXAS1;CYP3A43;CYP3A4;CYP3A5;CYP3A7-CYP3A51P	moderate;low;low;low;low	NA	transmembrane protein	NA	"The gene Cyp6a20 is referred to in FlyBase by the symbol Dmel\Cyp6a20 (CG10245, FBgn0033980). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:14882118..14884046. It has the cytological map location 51D1. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Its molecular function is described by: heme binding; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; oxidoreductase activity. It is involved in the biological process described with: aggressive behavior; oxidation-reduction process; defense response to Gram-negative bacterium. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during late pupal stages.  "
FBgn0031449	CG31689	-0.381225687	0.310979784	0.999936032	NA	ABCG1;ABCG4	moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31689 (FBgn0031449). It is a protein_coding_gene from Drosophila melanogaster. It has 8 annotated transcripts and 8 polypeptides (2 unique). Gene sequence location is 2L:2725674..2739830. It has the cytological map location 23A3. Protein features are: AAA+ ATPase domain; ABC transporter, conserved site; ABC transporter-like; ABC-2 type transporter; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: sterol-transporting ATPase activity; ATPase activity, coupled to transmembrane movement of substances; ATP binding; cholesterol transporter activity. It is involved in the biological process described with: transmembrane transport. 10 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0259993	CR42491	-0.381169885	0.265543987	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CR42491 (FBgn0259993). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is X:762615..763810. It has the cytological map location 1C4. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 06-12 hour embryonic stages, during early larval stages.  "
FBgn0038196	CG9922	-0.380793612	0.298250203	0.999936032	NA	HYPK	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9922 (FBgn0038196). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:14035018..14036398. It has the cytological map location 88A4. Its molecular function is described by: . It is involved in the biological process described with: . 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0261955	kdn	-0.38070339	0.263023748	0.999936032	NA	CS	high	NA	NA	NA	"The gene knockdown is referred to in FlyBase by the symbol Dmel\kdn (CG3861, FBgn0261955). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:6350629..6361323. It has the cytological map location 5F2-5F4. Protein features are: Citrate synthase; Citrate synthase active site; Citrate synthase, eukaryotic-type; Citrate synthase-like, large alpha subdomain; Citrate synthase-like, small alpha subdomain. Its molecular function is described by: citrate (Si)-synthase activity. It is involved in the biological process described with: tricarboxylic acid cycle; carbohydrate metabolic process. 30 alleles are reported. The phenotypes of these alleles manifest in: wing; eye photoreceptor cell. The phenotypic classes of alleles include: lethal - all die before end of first instar larval stage; lethal - all die before end of larval stage; increased mortality; lethal - all die before end of second instar larval stage."
FBgn0031191	Cp110	-0.38069331	0.364790644	0.999936032	NA	CCP110	high	NA	NA	NA	"The gene Centriolar coiled coil protein 110kDa is referred to in FlyBase by the symbol Dmel\Cp110 (CG14617, FBgn0031191). It is a protein_coding_gene from Drosophila melanogaster. It has 8 annotated transcripts and 8 polypeptides (3 unique). Gene sequence location is X:22482082..22487458. It has the cytological map location 20C1. Protein features are: Centriolar coiled-coil protein of 110kDa; IQ motif, EF-hand binding site. Its molecular function is unknown. It is involved in the biological process described with: negative regulation of centriole elongation; centriole replication; regulation of cytokinesis. 13 alleles are reported. The phenotypes of these alleles manifest in: spermatocyte; wing disc; centriole; axoneme; male germline stem cell. The phenotypic classes of alleles include: viable; fertile; lethal - all die before end of pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0038860	Ice2	-0.380447499	0.362724163	0.999936032	NA	ICE2	low	NA	NA	NA	"The gene Interacts with the C terminus of ELL 2 is referred to in FlyBase by the symbol Dmel\Ice2 (CG10825, FBgn0038860). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:21130216..21132720. It has the cytological map location 93C1. Protein features are: Little elongation complex subunit 2 , C-terminal. Its molecular function is described by: . It is involved in the biological process described with: . 4 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: partially lethal - majority die; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0037073	Tsr1	-0.380437781	0.286419488	0.999936032	NA	TSR1	high	NA	NA	NA	"The gene Tsr1 ribosome assembly factor is referred to in FlyBase by the symbol Dmel\Tsr1 (CG7338, FBgn0037073). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:21335215..21338232. It has the cytological map location 78C7-78C8. Protein features are: AARP2CN; Armadillo-like helical; Bms1/Tsr1-type G domain; Ribosome biogenesis protein BMS1/TSR1, C-terminal. Its molecular function is described by: GTPase activity; GTP binding; U3 snoRNA binding. It is involved in the biological process described with: positive regulation of peptide hormone secretion; ribosome assembly; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); positive regulation of multicellular organism growth. 6 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; embryonic/larval neuroblast. The phenotypic classes of alleles include: lethal - all die before end of P-stage; lethal - all die before end of pupal stage; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0029897	RpL17	-0.380329276	0.263495849	0.999936032	NA	RPL17;RPL17-C18orf32	high;moderate	NA	NA	NA	"The gene Ribosomal protein L17 is referred to in FlyBase by the symbol Dmel\RpL17 (CG3203, FBgn0029897). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is X:6741537..6744238. It has the cytological map location 6C10. Protein features are: Ribosomal protein L22/L17; Ribosomal protein L22/L17, conserved site; Ribosomal protein L22/L17, eukaryotic/archaeal. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: translation; cytoplasmic translation. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal; some die during larval stage; viable; lethal - all die during larval stage; fertile; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, in adult female stages.  "
FBgn0031127	CG1835	-0.380214511	0.303175873	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1835 (FBgn0031127). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:20661917..20669669. It has the cytological map location 19E1. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0266361	CR45009	-0.380214511	0.303175873	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45009 (FBgn0266361). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is X:23007672..23009452. It has the cytological map location 20F3. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0035244	ABCB7	-0.379732074	0.272740053	0.999936032	NA	ABCB7;ABCB6	high;low	NA	transmembrane protein	NA	"The gene ATP binding cassette subfamily B member 7 is referred to in FlyBase by the symbol Dmel\ABCB7 (CG7955, FBgn0035244). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:1618414..1623413. It has the cytological map location 62A8-62A9. Protein features are: AAA+ ATPase domain; ABC transporter type 1, transmembrane domain; ABC transporter, conserved site; ABC transporter-like; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: heme transporter activity; ATP binding; ATPase activity, coupled to transmembrane movement of substances. It is involved in the biological process described with: iron-sulfur cluster assembly; transmembrane transport; cellular iron ion homeostasis; heme transport. 9 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0021750	SerRS-m	-0.37961569	0.331171422	0.999936032	NA	SARS2;SARS	high;low	NA	NA	NA	"The gene Seryl-tRNA synthetase, mitochondrial is referred to in FlyBase by the symbol Dmel\SerRS-m (CG4938, FBgn0021750). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:15340667..15343218. It has the cytological map location 88F1. Protein features are: Aminoacyl-tRNA synthetase, class II; Aminoacyl-tRNA synthetase, class II (G/ P/ S/T); Serine-tRNA ligase catalytic core domain; Serine-tRNA ligase, type1. Its molecular function is described by: serine-tRNA ligase activity; ATP binding. It is involved in the biological process described with: seryl-tRNA aminoacylation; mitochondrial seryl-tRNA aminoacylation. 4 alleles are reported. The phenotypes of these alleles manifest in: mitochondrial matrix; 1st posterior cell; mitochondrial crista; anterior crossvein; mitochondrion; wing. The phenotypic classes of alleles include: viable; lethal - all die during P-stage; visible; short lived; lethal; locomotor behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0035089	Phk-3	-0.379501016	0.361123555	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Pherokine 3 is referred to in FlyBase by the symbol Dmel\Phk-3 (CG9358, FBgn0035089). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:24970843..24973207. It has the cytological map location 60E11. Protein features are: Insect odorant-binding protein A10/Ejaculatory bulb-specific protein 3. Its molecular function is unknown. It is involved in the biological process described with: metamorphosis; response to bacterium. 7 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of low expression.  Peak expression observed during early pupal stages.  "
FBgn0035630	CG10576	-0.379266298	0.267317611	0.999936032	NA	PA2G4	high	Maybe TF	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10576 (FBgn0035630). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3L:5761963..5765702. It has the cytological map location 64E6. Protein features are: PA2G4 family; Peptidase M24; Winged helix-turn-helix DNA-binding domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. The phenotype of these alleles manifest in: presumptive embryonic/larval muscle system. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages.  "
FBgn0030575	CG5321	-0.379191639	0.342863691	0.999936032	NA	BBOX1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5321 (FBgn0030575). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:14679568..14681418. It has the cytological map location 12F2. Protein features are: Domain of unknown function DUF971; TauD/TfdA-like domain. Its molecular function is described by: oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-18 embryonic stages, during early larval stages, during early pupal stages, in adult female stages.  "
FBgn0036538	CG15715	-0.378758259	0.27848774	0.999936032	NA	ZNF706	high	DNA-binding with transcription factor activity	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15715 (FBgn0036538). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:15835693..15837482. It has the cytological map location 72A2. Protein features are: At2g23090-like; Uncharacterised protein family SERF. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during late pupal stages, in adult female stages.  "
FBgn0028658	Adat1	-0.378306625	0.341531852	0.999936032	NA	ADAT1;ADARB1;ADAR;ADARB2	high;low;moderate;low	NA	NA	NA	"The gene Adenosine deaminase, tRNA-specific 1 is referred to in FlyBase by the symbol Dmel\Adat1 (CG16889, FBgn0028658). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:13808360..13811474. It has the cytological map location 34D1. Protein features are: Adenosine deaminase/editase. Its molecular function is described by: tRNA-specific adenosine deaminase activity; RNA binding. It is involved in the biological process described with: tRNA processing; tRNA modification. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of very low expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.  "
FBgn0028494	CG6424	-0.377915147	0.295028539	0.999936032	NA	FAM13C;FAM13A;FAM13B	high;high;moderate	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG6424 (FBgn0028494). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2R:17703335..17719346. It has the cytological map location 54E1. Its molecular function is described by: . It is involved in the biological process described with: . 21 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed in adult male stages.
FBgn0027525	LTV1	-0.377530935	0.284227937	0.999936032	NA	LTV1	high	NA	NA	NA	"The gene LTV1 ribosome biogenesis factor is referred to in FlyBase by the symbol Dmel\LTV1 (CG7686, FBgn0027525). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:10836570..10838727. It has the cytological map location 47C3. Protein features are: Low temperature viability protein. Its molecular function is described by: protein binding. It is involved in the biological process described with: ribosomal small subunit biogenesis; DNA endoreduplication; rRNA processing; positive regulation of cell size; ribosomal small subunit export from nucleus; cell growth. 5 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum. The phenotypic classes of alleles include: phenotype; increased mortality; some die during P-stage; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, during early larval stages.  "
FBgn0034496	CG9143	-0.377404705	0.316529276	0.999936032	DDX24	DDX24	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9143 (FBgn0034496). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:20275973..20278915. It has the cytological map location 56F14-56F15. Protein features are: DEAD/DEAH box helicase domain; Helicase superfamily 1/2, ATP-binding domain; Helicase, C-terminal; P-loop containing nucleoside triphosphate hydrolase; RNA helicase, DEAD-box type, Q motif. Its molecular function is described by: nucleic acid binding; ATP binding; ATP-dependent RNA helicase activity. It is involved in the biological process described with: RNA secondary structure unwinding. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0004959	phm	-0.377338544	0.161316898	0.999936032	NA	CYP2D6;CYP2C8;CYP2C9;CYP2A13;CYP2B6;CYP2W1;CYP2C18;CYP2A7;CYP2E1;CYP2S1;CYP2C19;CYP2A6;CYP2R1;CYP2F1;CYP2U1;CYP1A1;CYP1A2;CYP1B1	moderate;moderate;moderate;high;moderate;high;moderate;high;high;moderate;moderate;high;moderate;moderate;moderate;high;high;moderate	NA	transmembrane protein	NA	"The gene phantom is referred to in FlyBase by the symbol Dmel\phm (CG6578, FBgn0004959). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:18685766..18688433. It has the cytological map location 17D1. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Its molecular function is described by: ecdysteroid 25-hydroxylase activity; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; heme binding. It is involved in the biological process described with: embryonic development via the syncytial blastoderm; oogenesis; border follicle cell migration; ecdysone biosynthetic process; oxidation-reduction process. 19 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval hindgut; midgut primordium; sensory system neuron; presumptive embryonic/larval central nervous system; external sensory organ; tract; presumptive embryonic/larval nervous system; external sensillum; presumptive embryonic/larval digestive system; cell cluster organ; presumptive embryonic/larval integumentary system; segmental subdivision of integument; embryonic head; epithelial cell. The phenotypic classes of alleles include: increased mortality; phenotype; increased mortality during development; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0030851	CG8326	-0.377019706	0.35892025	0.999936032	NA	CCDC137	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8326 (FBgn0030851). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:17628164..17629492. It has the cytological map location 16B9-16B10. Protein features are: Coiled-coil domain-containing protein 137. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; embryonic/larval neuroblast; ganglion mother cell; trichogen cell. The phenotypic classes of alleles include: phenotype; increased mortality during development; increased mortality; some die during P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0051233	CG31233	-0.376883679	0.266404207	0.999936032	NA	ANPEP;NPEPPS;TRHDE;LVRN;ENPEP	moderate;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31233 (FBgn0051233). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:21749853..21753237. It has the cytological map location 93F8. Protein features are: Aminopeptidase N-type; ERAP1-like C-terminal domain; Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase; Peptidase M1, membrane alanine aminopeptidase, N-terminal. Its molecular function is described by: metallopeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0085313	CG34284	-0.37665541	0.17684517	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG34284 (FBgn0085313). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:18902338..18902933. It has the cytological map location 91D4. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during late pupal stages.  "
FBgn0036301	CG4069	-0.376281316	0.36539868	0.999936032	NA	KLHDC4;LOC105371397	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4069 (FBgn0036301). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:12535426..12537315. It has the cytological map location 69C6. Protein features are: Galactose oxidase, beta-propeller; Kelch repeat type 2; Kelch-type beta propeller. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: visible; lethal - all die during P-stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0086367	t	-0.375743168	0.36878867	0.999936032	NA	NA	NA	NA	NA	NA	"The gene tan is referred to in FlyBase by the symbol Dmel\t (CG12120, FBgn0086367). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:9217655..9223257. It has the cytological map location 8D1. Protein features are: Peptidase C45. Its molecular function is described by: hydrolase activity; beta-alanyl-histamine hydrolase activity; beta-alanyl-dopamine hydrolase activity. It is involved in the biological process described with: dopamine biosynthetic process; histamine biosynthetic process; cuticle pigmentation; adult chitin-containing cuticle pigmentation; flight behavior; visual perception; histamine metabolic process. 26 alleles are reported. The phenotypes of these alleles manifest in: synaptic vesicle; eye; adult cuticle; photoreceptor cell; retina; mesothoracic tergum. The phenotypic classes of alleles include: body color defective; fertile; viable; visual behavior defective; phenotype; neurophysiology defective; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages.  "
FBgn0039359	RpL27	-0.375672592	0.270660762	0.999936032	RPL27	RPL27	high	NA	NA	NA	"The gene Ribosomal protein L27 is referred to in FlyBase by the symbol Dmel\RpL27 (CG4759, FBgn0039359). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 3R:25683623..25685051. It has the cytological map location 96E9-96E10. Protein features are: KOW; Ribosomal protein L2 domain 2; Ribosomal protein L27e; Ribosomal protein L27e, conserved site; Translation protein SH3-like domain. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; translation. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; lethal - all die during larval stage; viable; some die during larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0010620	CG10939	-0.375566434	0.28847249	0.999936032	NA	SLC9A3R2;SLC9A3R1;PDZK1;PDZD3	high;moderate;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10939 (FBgn0010620). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:17394593..17405171. It has the cytological map location 54B6-54B7. Protein features are: Na(+)/H(+) exchange regulatory cofactor NHERF-4; PDZ domain. Its molecular function is described by: guanylate cyclase inhibitor activity. It is involved in the biological process described with: receptor guanylyl cyclase signaling pathway; actin cytoskeleton organization; ion transport; olfactory behavior. 16 alleles are reported. The phenotypes of these alleles manifest in: wing vein L3; filamentous actin; follicle cell; wing vein. The phenotypic classes of alleles include: viable; visible; smell perception defective; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 12-24 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0033434	CG1902	-0.375366912	0.271490246	0.999936032	NA	TTPAL;CLVS1;RLBP1;CLVS2;TTPA	moderate;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1902 (FBgn0033434). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:9594045..9605624. It has the cytological map location 45F6. Protein features are: CRAL-TRIO lipid binding domain; CRAL/TRIO, N-terminal domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed during late larval stages, during late pupal stages, in adult male stages.  "
FBgn0046214	vig2	-0.375338221	0.275088856	0.999936032	NA	SERBP1;HABP4	high;moderate	NA	NA	NA	"The gene vig2 is referred to in FlyBase by the symbol Dmel\vig2 (CG11844, FBgn0046214). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3R:25123373..25125619. It has the cytological map location 96C1. Protein features are: Hyaluronan/mRNA-binding protein. Its molecular function is unknown. It is involved in the biological process described with: regulation of chromatin silencing; histone H3-K9 methylation; heterochromatin organization. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; some die during P-stage; viable; suppressor of variegation; lethal - all die before end of P-stage; enhancer of variegation. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-06 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0051288	CG31288	-0.375242674	0.273403158	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31288 (FBgn0051288). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:25297960..25299557. It has the cytological map location 96D1. Protein features are: CHK kinase-like; Protein kinase-like domain; Protein of unknown function DUF227. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, in stages of adults of both sexes.  "
FBgn0034638	CG10433	-0.374842629	0.294609644	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10433 (FBgn0034638). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2R:21605676..21608125. It has the cytological map location 57F3. Its molecular function is described by: . It is involved in the biological process described with: multicellular organism reproduction; regulation of female receptivity; defense response. 7 alleles are reported. The phenotype of these alleles manifest in: spindle. The phenotypic classes of alleles include: lethal; viable; some die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during late pupal stages, in adult male stages.  "
FBgn0029088	disp	-0.37445592	0.368678067	0.999936032	NA	DISP1;DISP2;DISP3	high;moderate;moderate	NA	transmembrane protein	NA	"The gene dispatched is referred to in FlyBase by the symbol Dmel\disp (CG2019, FBgn0029088). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:5849697..5856311. It has the cytological map location 83C5. Protein features are: Protein dispatched; Protein patched/dispatched; Sterol-sensing domain. Its molecular function is unknown. It is involved in the biological process described with: smoothened signaling pathway; exocytosis; pole cell migration. 14 alleles are reported. The phenotypes of these alleles manifest in: embryonic/first instar larval cuticle; wing; denticle; 1st posterior cell; eye; denticle belt. The phenotypic classes of alleles include: wild-type; increased mortality; visible; viable; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0051821	CG31821	-0.374242038	0.278135925	0.999936032	NA	SCPEP1	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31821 (FBgn0051821). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:15900935..15902410. It has the cytological map location 35D6. Protein features are: Alpha/Beta hydrolase fold; Peptidase S10, serine carboxypeptidase; Serine carboxypeptidase, serine active site. Its molecular function is described by: serine-type carboxypeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process. 3 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, in adult male stages.  "
FBgn0035607	CG4835	-0.374206775	0.362707438	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4835 (FBgn0035607). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:5479790..5483663. It has the cytological map location 64D2. Protein features are: Chitin binding domain. Its molecular function is described by: chitin binding. It is involved in the biological process described with: chitin metabolic process. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0042126	CG18788	-0.373737975	0.319504851	0.999936032	NA	SLC17A5;SLC17A4;SLC17A3;SLC17A2;SLC17A1	low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG18788 (FBgn0042126). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:12034190..12036131. It has the cytological map location 33B9. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain. Its molecular function is described by: transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; anion transport. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed during late larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0026197	noe	-0.37358564	0.340746013	0.999936032	NA	NA	NA	NA	NA	NA	"The gene noe is referred to in FlyBase by the symbol Dmel\noe (CR32172, FBgn0026197). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3L:17400272..17401348. It has the cytological map location 74B1. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed in adult male stages.  "
FBgn0036848	CG10424	-0.373573674	0.295347551	0.999936032	CARKD	NAXD	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10424 (FBgn0036848). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:19096399..19097709. It has the cytological map location 75F7. Protein features are: ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Carbohydrate kinase, predicted, conserved site; Ribokinase-like. Its molecular function is described by: ADP-dependent NAD(P)H-hydrate dehydratase activity. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; lethal; viable; lethal - all die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed during late pupal stages.  "
FBgn0264386	Ca-alpha1T	-0.373539174	0.373036087	0.999936032	NA	CACNA1I;CACNA1G;CACNA1H	high;moderate;moderate	NA	transmembrane protein	NA	"The gene Ca<sup>2+</sup>-channel protein ‘±<down>1</down> subunit T is referred to in FlyBase by the symbol Dmel\Ca-‘±1T (CG15899, FBgn0264386). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (all unique). Gene sequence location is X:6104085..6192483. It has the cytological map location 5D5-5D6. Protein features are: Ion transport domain; Voltage-dependent calcium channel, T-type, alpha-1 subunit; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: voltage-gated sodium channel activity; low voltage-gated calcium channel activity. It is involved in the biological process described with: membrane depolarization during action potential; neuronal action potential; calcium ion transmembrane transport via low voltage-gated calcium channel; calcium ion transmembrane transport. 22 alleles are reported. The phenotype of these alleles manifest in: indirect flight muscle motor neuron MN5. The phenotypic classes of alleles include: neurophysiology defective; phenotype; lethal - all die before end of P-stage; behavior defective."
FBgn0026079	Nsun2	-0.373371683	0.303136673	0.999936032	NA	NSUN2	high	NA	NA	NA	"The gene NOP2-Sun domain family, member 2 is referred to in FlyBase by the symbol Dmel\Nsun2 (CG6133, FBgn0026079). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:4111156..4113734. It has the cytological map location 4A5-4A6. Protein features are: Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site; RNA (C5-cytosine) methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase; SAM-dependent methyltransferase RsmB/NOP2-type; tRNA (C5-cytosine) methyltransferase, NCL1. Its molecular function is described by: tRNA (cytosine-5-)-methyltransferase activity; tRNA binding. It is involved in the biological process described with: short-term memory; RNA methylation; tRNA methylation. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: male fertile; viable; female semi-fertile; memory defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 06-12 hour embryonic stages, during early larval stages.  "
FBgn0015834	eIF3i	-0.37333047	0.273608065	0.999936032	NA	EIF3I	high	NA	NA	NA	"The gene eukaryotic translation initiation factor 3 subunit i is referred to in FlyBase by the symbol Dmel\eIF3i (CG8882, FBgn0015834). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:4966367..4967775. It has the cytological map location 25B5. Protein features are: Eukaryotic translation initiation factor 3 subunit I; WD40 repeat; WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: translation initiation factor activity. It is involved in the biological process described with: translational initiation. 4 alleles are reported. The phenotypes of these alleles manifest in: sarcomere; Z disc. The phenotypic classes of alleles include: lethal; lethal - all die during larval stage; viable. Summary of modENCODE Temporal Expression Profile:  Very high expression at all stages of development.  "
FBgn0039588	mIF2	-0.372909554	0.351185229	0.999936032	NA	MTIF2	high	NA	NA	NA	"The gene mitochondrial translation initiation factor 2 is referred to in FlyBase by the symbol Dmel\mIF2 (CG12413, FBgn0039588). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:28542274..28544817. It has the cytological map location 98D4. Protein features are: P-loop containing nucleoside triphosphate hydrolase; Small GTP-binding protein domain; Transcription factor, GTP-binding domain; Translation initiation factor IF- 2; Translation initiation factor IF- 2, domain 3; Translation protein, beta-barrel domain. Its molecular function is described by: GTP binding; GTPase activity; tRNA binding; translation initiation factor activity. It is involved in the biological process described with: translational initiation; mitochondrial translation. 8 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in adult female stages.  "
FBgn0034366	Atg7	-0.372847909	0.370548089	0.999936032	ATG7	ATG7	high	NA	NA	NA	"The gene Autophagy-related 7 is referred to in FlyBase by the symbol Dmel\Atg7 (CG5489, FBgn0034366). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:18620466..18625044. It has the cytological map location 55E2. Protein features are: THIF-type NAD/FAD binding fold; Ubiquitin-like modifier-activating enzyme Atg7; Ubiquitin-like modifier-activating enzyme Atg7, N-terminal. Its molecular function is described by: Atg8 activating enzyme activity; Atg12 activating enzyme activity. It is involved in the biological process described with 20 unique terms, many of which group under: cellular response to nutrient levels; cellular response to external stimulus; cell development; piecemeal microautophagy of nucleus; response to external biotic stimulus; reproductive process; instar larval or pupal development; organelle assembly; regulation of immune system process; response to extracellular stimulus. 16 alleles are reported. The phenotypes of these alleles manifest in: female germline cyst; cell; larva; intracellular membrane-bounded organelle; adult tagma; major mitochondrial derivative; adult peripheral nervous system; embryonic/larval digestive system; pupal/adult digestive system; intracellular part; rhabdomere; organism subdivision; fat body; ovary; egg; membrane-bounded organelle; anterior-posterior subdivision of organism; anatomical cluster; cytoplasm. The phenotypic classes of alleles include: starvation stress response defective; phenotype; viable; decreased cell death; behavior defective; long lived; immune response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0036214	CG7264	-0.372774128	0.236924391	0.999936032	RIBC2	RIBC2;RIBC1	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7264 (FBgn0036214). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:11829030..11830844. It has the cytological map location 68E1. Protein features are: RIB43A. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the pupal period, in adult male stages.  "
FBgn0010238	Lac	-0.37221452	0.350274498	0.999936032	NA	NEGR1	high	NA	NA	NA	"The gene Lachesin is referred to in FlyBase by the symbol Dmel\Lac (CG12369, FBgn0010238). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:12453190..12465630. It has the cytological map location 49A6-49A7. Protein features are: Immunoglobulin I-set; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold. Its molecular function is described by: protein homodimerization activity. It is involved in the biological process described with: open tracheal system development; regulation of tube size, open tracheal system; maintenance of epithelial integrity, open tracheal system; septate junction assembly; homophilic cell adhesion via plasma membrane adhesion molecules; morphogenesis of embryonic epithelium; cell adhesion involved in heart morphogenesis. 18 alleles are reported. The phenotypes of these alleles manifest in: cell; acellular anatomical structure; central nervous system; apical junction complex; embryonic/larval transverse connective; glial cell; embryonic foregut; peripheral nervous system; cell-cell junction; organ system subdivision. The phenotypic classes of alleles include: viable; lethal - all die before end of embryonic stage; lethal; some die during pupal stage; lethal - all die before end of pupal stage; some die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-18 hour embryonic stages, during early pupal stages.  "
FBgn0265262	Vha68-1	-0.372046582	0.356837851	0.999936032	NA	ATP6V1A	high	NA	NA	NA	"The gene Vacuolar H<sup>+</sup> ATPase 68kD subunit 1 is referred to in FlyBase by the symbol Dmel\Vha68-1 (CG12403, FBgn0265262). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:13000770..13004107. It has the cytological map location 34B-34A4. Protein features are: ATP synthase subunit alpha-like domain; ATPase, F1/V1 complex, beta/alpha subunit, C-terminal; ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain; ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain; ATPase, V1 complex, subunit A; ATPase, alpha/beta subunit, nucleotide-binding domain, active site; ATPsynthase alpha/beta subunit, N-terminal extension; P-loop containing nucleoside triphosphate hydrolase; V-type ATP synthase catalytic alpha chain. Its molecular function is described by: ATP binding; proton-transporting ATPase activity, rotational mechanism. It is involved in the biological process described with: ATP hydrolysis coupled proton transport; ATP metabolic process; cellular response to hypoxia; vacuolar acidification; regulation of Notch signaling pathway. 17 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: partially lethal; partially lethal - majority die; lethal - all die during P-stage; viable; visible; body color defective."
FBgn0037101	CG7634	-0.371784689	0.249081963	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7634 (FBgn0037101). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:21565426..21567785. It has the cytological map location 78D6. Protein features are: Tetratricopeptide-like helical domain. Its molecular function is described by: . It is involved in the biological process described with: . 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0050026	CG30026	-0.3717768	0.33234352	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG30026 (FBgn0050026). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:11408576..11409449. It has the cytological map location 47F10. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed during early pupal stages.
FBgn0003435	sm	-0.371772827	0.348088519	0.999936032	NA	HNRNPL;HNRNPLL	high;moderate	NA	NA	NA	"The gene smooth is referred to in FlyBase by the symbol Dmel\sm (CG9218, FBgn0003435). It is a protein_coding_gene from Drosophila melanogaster. It has 21 annotated transcripts and 21 polypeptides (18 unique). Gene sequence location is 2R:19517864..19631508. It has the cytological map location 56D15-56E1. Protein features are: HnRNP-L/PTB; RNA recognition motif domain. Its molecular function is described by: RNA binding; mRNA binding. It is involved in the biological process described with: mRNA processing; axon guidance; adult feeding behavior; determination of adult lifespan. 38 alleles are reported. The phenotypes of these alleles manifest in: abdominal sternite bristle; microchaeta; Z disc; trichogen cell; myofibril; sarcomere; macrochaeta; acrostichal bristle; scutellar bristle. The phenotypic classes of alleles include: increased mortality; short lived; increased mortality during development; phenotype; male sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed in adult male stages.  "
FBgn0004028	wupA	-0.371721603	0.278933249	0.999936032	NA	TNNI2;TNNI1;TNNI3	high;high;high	NA	NA	NA	NA
FBgn0033564	Pex6	-0.371567757	0.349362522	0.999936032	NA	PEX6	high	NA	NA	NA	"The gene Peroxin 6 is referred to in FlyBase by the symbol Dmel\Pex6 (CG11919, FBgn0033564). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:10879974..10883202. It has the cytological map location 47C5. Protein features are: AAA+ ATPase domain; ATPase, AAA-type, conserved site; ATPase, AAA-type, core; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: ATP binding. It is involved in the biological process described with: peroxisome organization. 2 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed during early larval stages, at stages throughout the pupal period, in adult male stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0027790	GV1	-0.371273024	0.376120315	0.999936032	NA	NA	NA	NA	NA	NA	"The gene GV1 is referred to in FlyBase by the symbol Dmel\GV1 (CG12023, FBgn0027790). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:1810588..1822903. It has the cytological map location 62B4-62B6. Its molecular function is described by: DNA binding. It is involved in the biological process described with: . 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed at stages throughout the pupal period.  "
FBgn0037070	CG11309	-0.371250401	0.27513399	0.999936032	NA	SERHL2;SERHL	moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11309 (FBgn0037070). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (2 unique). Gene sequence location is 3L:21301785..21304658. It has the cytological map location 78C6. Protein features are: Alpha/Beta hydrolase fold; Alpha/beta hydrolase fold-1; EF-Hand 1, calcium-binding site. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed during late larval stages.  "
FBgn0015324	Vha26	-0.371191173	0.272870672	0.999936032	NA	ATP6V1E1;ATP6V1E2	high;moderate	NA	NA	NA	NA
FBgn0004394	pdm2	-0.370829351	0.363882995	0.999936032	NA	POU2F3;POU2F1;POU2F2;POU3F2;POU3F4;POU3F1;POU1F1;POU5F1;POU3F3	high;moderate;moderate;low;low;low;moderate;low;low	DNA-binding with transcription factor activity(Homeobox|Pou)	NA	NA	"The gene POU domain protein 2 is referred to in FlyBase by the symbol Dmel\pdm2 (CG12287, FBgn0004394). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 2L:12657165..12686306. It has the cytological map location 33F2-33F3. Protein features are: Homeobox domain; Homeobox domain-like; Homeobox, conserved site; Lambda repressor-like, DNA-binding domain; POU domain; POU-specific domain. Its molecular function is described by: sequence-specific DNA binding; DNA binding; transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding. It is involved in the biological process described with: regulation of transcription, DNA-templated; central nervous system development; generation of neurons; ectoderm development; neuroblast development. 25 alleles are reported. The phenotypes of these alleles manifest in: central nervous system; neuroblast NB3-3; stage 4 neuroblast; U3 neuron; neuroblast NB4-2; ganglion mother cell; abdominal segment 3; head; appendage; ganglion mother cell GMC4-2a; embryonic ganglion mother cell. The phenotypic classes of alleles include: neuroanatomy defective; partially lethal; fertile; lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0040323	GNBP1	-0.370289179	0.378313652	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Gram-negative bacteria binding protein 1 is referred to in FlyBase by the symbol Dmel\GNBP1 (CG6895, FBgn0040323). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:18675800..18677876. It has the cytological map location 75D6. Protein features are: Beta-1,3-glucan-binding protein, N-terminal; Concanavalin A-like lectin/glucanase domain; Glycoside hydrolase family 16. Its molecular function is described by: protein binding; signaling pattern recognition receptor activity; (1->3)-beta-D-glucan binding; polysaccharide binding; lipopolysaccharide binding; peptidoglycan binding. It is involved in the biological process described with: carbohydrate metabolic process; positive regulation of Toll signaling pathway; innate immune response-activating signal transduction; immune response; peptidoglycan catabolic process; defense response to Gram-positive bacterium; innate immune response; regulation of innate immune response. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable; lethal - all die during embryonic stage; immune response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed during early pupal stages.  "
FBgn0038414	CG6901	-0.370227669	0.284313569	0.999936032	NA	SLC2A12;SLC2A13;SLC2A8;SLC2A6;SLC2A10	low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6901 (FBgn0038414). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:16323415..16325128. It has the cytological map location 89B12. Protein features are: Major facilitator superfamily domain; Major facilitator,  sugar transporter-like. Its molecular function is described by: transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; sensory perception of pain. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during late larval stages.  "
FBgn0050479	CG30479	-0.369403029	0.29548104	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG30479 (FBgn0050479). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:14674465..14678136. It has the cytological map location 51B10. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages.
FBgn0035665	Jon65Aiii	-0.369284696	0.274089074	0.999936032	NA	CTRB1	low	NA	NA	NA	"The gene Jonah 65Aiii is referred to in FlyBase by the symbol Dmel\Jon65Aiii (CG6483, FBgn0035665). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:6050757..6051690. It has the cytological map location 65A3. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: endopeptidase activity; serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of extremely low expression.  Peak expression observed during late larval stages, in stages of adults of both sexes.  "
FBgn0086356	tum	-0.368584077	0.369456679	0.999936032	NA	RACGAP1	high	NA	NA	NA	"The gene tumbleweed is referred to in FlyBase by the symbol Dmel\tum (CG13345, FBgn0086356). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:13856150..13858689. It has the cytological map location 49C-50D. Protein features are: Protein kinase C-like, phorbol ester/diacylglycerol-binding domain; Rho GTPase activation protein; Rho GTPase-activating protein domain. Its molecular function is described by: GTPase activator activity. It is involved in the biological process described with 15 unique terms, many of which group under: regulation of response to stimulus; cell cycle; somatic muscle development; regulation of GTPase activity; cell proliferation; regulation of cell division; anatomical structure morphogenesis; mitotic cell cycle; regulation of developmental process; regulation of signaling. 42 alleles are reported. The phenotypes of these alleles manifest in: epithelium; cell part; somatic precursor cell; plasma membrane bounded cell projection; embryonic/larval nervous system; wing posterior compartment; intracellular; male germline cell; syncytium; denticle row; organelle; non-connected developing system. The phenotypic classes of alleles include: partially lethal; increased mortality during development; phenotype; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0263863	mRpL45	-0.368390923	0.291215212	0.999936032	NA	MRPL45	high	NA	NA	NA	"The gene mitochondrial ribosomal protein L45 is referred to in FlyBase by the symbol Dmel\mRpL45 (CG6949, FBgn0263863). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:22618492..22619826. It has the cytological map location 94B6. Protein features are: NTF2-like domain; Tim44-like domain. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation. 5 alleles are reported. The phenotypes of these alleles manifest in: eye disc; imaginal disc; trichogen cell; eye. The phenotypic classes of alleles include: partially lethal; some die during larval stage; visible; viable; lethal; lethal - all die before end of larval stage."
FBgn0014141	cher	-0.368355899	0.375174802	0.999936032	NA	FLNA;FLNC;FLNB	high;moderate;moderate	NA	NA	NA	"The gene cheerio is referred to in FlyBase by the symbol Dmel\cher (CG3937, FBgn0014141). It is a protein_coding_gene from Drosophila melanogaster. It has 10 annotated transcripts and 10 polypeptides (8 unique). Gene sequence location is 3R:17091533..17125389. It has the cytological map location 89E12-89F1. Protein features are: Actinin-type actin-binding domain, conserved site; Calponin homology domain; Filamin/ABP280 repeat; Filamin/ABP280 repeat-like; Immunoglobulin E-set; Immunoglobulin-like fold. Its molecular function is described by: actin binding. It is involved in the biological process described with 16 unique terms, many of which group under: learning or memory; response to chemical; macromolecule localization; response to alcohol; immune system development; regulation of cytoskeleton organization; multicellular organism aging; chemosensory behavior; behavioral response to ethanol; positive regulation of biological process; tissue development. 41 alleles are reported. The phenotypes of these alleles manifest in: nurse cell ring canal; indirect flight muscle; intersegmental nerve; non-connected functional system; I band; female germline cell; eye; mesothoracic segment; lamellocyte; skeletal muscle of thorax; embryonic/larval peripheral nervous system. The phenotypic classes of alleles include: visible; phenotype; fertile; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 12-18 embryonic stages, during late larval stages, during late pupal stages.  "
FBgn0031566	CG2818	-0.368234895	0.345229537	0.999936032	GPCPD1	GPCPD1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG2818 (FBgn0031566). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:3713360..3716810. It has the cytological map location 24C1. Protein features are: Carbohydrate binding module family 20; Carbohydrate-binding-like fold; Glycerophosphocholine phosphodiesterase GPCPD1, CBM20 domain; Glycerophosphodiester phosphodiesterase Gde1; Glycerophosphodiester phosphodiesterase domain; Immunoglobulin-like fold; PLC-like phosphodiesterase, TIM beta/alpha-barrel domain; Phosphatidylinositol-specific phospholipase C, X domain. Its molecular function is described by: glycerophosphodiester phosphodiesterase activity; starch binding; glycerophosphocholine phosphodiesterase activity. It is involved in the biological process described with: cellular phosphate ion homeostasis; glycerophospholipid catabolic process. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0037248	srl	-0.367965574	0.319768522	0.999936032	NA	PPARGC1A;PPRC1;PPARGC1B	high;moderate;moderate	NA	NA	NA	"The gene spargel is referred to in FlyBase by the symbol Dmel\srl (CG9809, FBgn0037248). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:4422483..4429335. It has the cytological map location 82B1. Protein features are: PGC-1; RNA recognition motif domain. Its molecular function is described by: RNA polymerase II transcription cofactor activity; mRNA binding; nucleic acid binding; transcription factor binding; ligand-dependent nuclear receptor transcription coactivator activity. It is involved in the biological process described with: positive regulation of transcription from RNA polymerase II promoter; response to oxidative stress; positive regulation of sequence-specific DNA binding transcription factor activity; tissue homeostasis; regulation of transcription, DNA-templated; negative regulation of insulin receptor signaling pathway; energy homeostasis; insulin receptor signaling pathway; regulation of mitochondrion organization; positive regulation of cell growth. 22 alleles are reported. The phenotypes of these alleles manifest in: compound sense organ; gonad; segment; fat body; ommatidium; lipid particle; mechanosensory chaeta; reproductive system; eo-type sensillum; mitochondrial envelope; muscle system. The phenotypic classes of alleles include: cell size defective; sterile; locomotor behavior defective; visible; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0036035	CG18178	-0.367230544	0.323970526	0.999936032	NA	MAK16	low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG18178 (FBgn0036035). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:9717786..9719144. It has the cytological map location 67C5. Protein features are: RNA recognition motif domain. Its molecular function is described by: nucleic acid binding. It is involved in the biological process described with: maturation of 5.8S rRNA; maturation of LSU-rRNA. 6 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.
FBgn0038928	Fadd	-0.36707203	0.347863295	0.999936032	NA	PIDD1;FADD	low;low	NA	NA	NA	"The gene Fas-associated death domain is referred to in FlyBase by the symbol Dmel\Fadd (CG12297, FBgn0038928). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:22034455..22035617. It has the cytological map location 94A1. Protein features are: Death domain; Death-like domain. Its molecular function is described by: protein binding; CARD domain binding. It is involved in the biological process described with: peptidoglycan recognition protein signaling pathway; positive regulation of innate immune response; sperm individualization; positive regulation of antibacterial peptide biosynthetic process; activation of cysteine-type endopeptidase activity involved in apoptotic process; apoptotic process; immune response; defense response to Gram-negative bacterium; positive regulation of defense response to virus by host. 14 alleles are reported. The phenotype of these alleles manifest in: spermatid. The phenotypic classes of alleles include: viable; fertile; wild-type; immune response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0037671	VhaM8.9	-0.367015883	0.278230212	0.999936032	ATP6AP2	ATP6AP2	high	NA	transmembrane protein	NA	"The gene Vacuolar H<sup>+</sup> ATPase M8.9 accessory subunit is referred to in FlyBase by the symbol Dmel\VhaM8.9 (CG8444, FBgn0037671). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:9260638..9262590. It has the cytological map location 85D6-85D7. Protein features are: Renin receptor-like. Its molecular function is described by: frizzled-2 binding; receptor activity; frizzled binding. It is involved in the biological process described with 15 unique terms, many of which group under: trans-synaptic signaling; ion transport; phototaxis; single-organism intracellular transport; protein localization involved in establishment of planar polarity; axo-dendritic transport; anterograde trans-synaptic signaling; regulation of anatomical structure morphogenesis; hydrogen transport; taxis. 16 alleles are reported. The phenotypes of these alleles manifest in: adult head sensillum; wing vein; neuron part; presynaptic active zone; wing hair; presynapse; pigment cell; cell part; adult peripheral nervous system; wing sensillum; cell. The phenotypic classes of alleles include: some die during larval stage; phenotype; increased mortality during development; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0033989	CG7639	-0.366949247	0.309484811	0.999936032	NA	SAMM50	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7639 (FBgn0033989). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:14987660..14992230. It has the cytological map location 51D7. Protein features are: Bacterial surface antigen (D15); POTRA domain. Its molecular function is described by: . It is involved in the biological process described with: . 6 alleles are reported. The phenotypes of these alleles manifest in: sarcomere; myofibril; trichogen cell; indirect flight muscle. The phenotypic classes of alleles include: flightless; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0032010	CG8086	-0.366823362	0.360154259	0.999936032	NA	ODF3;ODF3B;ODF3L2	high;moderate;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8086 (FBgn0032010). It is a protein_coding_gene from Drosophila melanogaster. It has 12 annotated transcripts and 12 polypeptides (all unique). Gene sequence location is 2L:8244160..8257502. It has the cytological map location 28F5-29A1. Protein features are: Sperm-tail PG-rich repeat. Its molecular function is unknown. It is involved in the biological process described with: sensory perception of sound. 11 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; mesothoracic tergum. The phenotypic classes of alleles include: increased mortality; lethal - all die during P-stage; phenotype; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during late pupal stages, in adult male stages.  "
FBgn0033919	CG8547	-0.366206445	0.321918343	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8547 (FBgn0033919). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:14261206..14267919. It has the cytological map location 50E6. Its molecular function is unknown. The biological processes in which it is involved are not known. 9 alleles are reported. The phenotypes of these alleles manifest in: sarcomere; embryonic/larval somatic muscle. The phenotypic classes of alleles include: partially lethal - majority die; lethal - all die during larval stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during late pupal stages.  "
FBgn0020880	CG7179	-0.366186956	0.324550483	0.999936032	NA	TNFAIP6	low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG7179 (FBgn0020880). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:7775804..7778029. It has the cytological map location 28C3. Protein features are: CUB domain; Transcription activator LAG-3; WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. It is involved in the biological process described with: synaptic target recognition. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages.
FBgn0024364	CG11417	-0.366112759	0.310336251	0.999936032	ESF1	ESF1	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG11417 (FBgn0024364). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:1354014..1356473. It has the cytological map location 1F4. Protein features are: NUC153. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; mesothoracic tergum; Z disc; sarcomere. The phenotypic classes of alleles include: lethal; increased mortality; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0052262	CG32262	-0.365799241	0.319415368	0.999936032	NA	MPV17L2;PXMP2;MPV17	moderate;low;low	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG32262 (FBgn0052262). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:3809146..3810196. It has the cytological map location 63F1. Protein features are: Mpv17/PMP22. Its molecular function is described by: . It is involved in the biological process described with: mitochondrial ribosome assembly. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during pupal stage; partially lethal - majority die; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed in adult male stages.
FBgn0050069	CG30069	-0.365429877	0.312470185	0.999936032	NA	TXN;TXNDC2;AHNAK;TXNDC8;AHNAK2	low;low;low;low;low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG30069 (FBgn0050069). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:14185204..14198368. It has the cytological map location 50E1-50E3. Its molecular function is described by: . It is involved in the biological process described with: wing disc development. 6 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: viable; lethal - all die before end of embryonic stage; lethal; some die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages.
FBgn0033584	CG7737	-0.36498511	0.340863327	0.999936032	NA	KDM1B	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7737 (FBgn0033584). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:11222871..11226746. It has the cytological map location 47E1. Protein features are: Amine oxidase; FAD/NAD(P)-binding domain. Its molecular function is described by: oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 and 12-18 hour embryonic stages, during early larval stages, during late pupal stages, in adult female stages.  "
FBgn0001142	Gs1	-0.364677227	0.301262391	0.999936032	NA	GLUL;LGSN	moderate;moderate	NA	NA	NA	"The gene Glutamine synthetase 1 is referred to in FlyBase by the symbol Dmel\Gs1 (CG2718, FBgn0001142). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:132077..134472. It has the cytological map location 21B2-21B3. Protein features are: Glutamine synthetase, N-terminal conserved site; Glutamine synthetase, beta-Grasp domain; Glutamine synthetase, catalytic domain; Glutamine synthetase, glycine-rich site; Glutamine synthetase/guanido kinase, catalytic domain. Its molecular function is described by: glutamate-ammonia ligase activity. It is involved in the biological process described with: mitochondrion organization; phagocytosis; glutamine biosynthetic process; glutamine metabolic process. 21 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: increased mortality; lethal - all die during P-stage; phenotype; increased mortality during development; lethal - all die before end of first instar larval stage; immune response defective; wild-type. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, during early pupal stages.  "
FBgn0260482	CG32599	-0.364216173	0.366151904	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32599 (FBgn0260482). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:14243686..14246514. It has the cytological map location 12E5. Its molecular function is described by: . It is involved in the biological process described with: . 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period.  "
FBgn0026409	Mpcp2	-0.364106106	0.282400814	0.999936032	NA	SLC25A3	moderate	NA	NA	NA	"The gene Mitochondrial phosphate carrier protein 2 is referred to in FlyBase by the symbol Dmel\Mpcp2 (CG4994, FBgn0026409). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3L:14537651..14540441. It has the cytological map location 70E1. Protein features are: Mitochondrial carrier domain; Mitochondrial substrate/solute carrier. Its molecular function is described by: phosphate ion transmembrane transporter activity. It is involved in the biological process described with: wing disc dorsal/ventral pattern formation; phosphate ion transport; mitochondrial transport. 8 alleles are reported. The phenotypes of these alleles manifest in: prothoracic leg sensillum; metathoracic leg sensillum; trichogen cell; antennal sense organ; mesothoracic leg sensillum. The phenotypic classes of alleles include: pain response defective; lethal; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed during early larval stages.  "
FBgn0034688	CG11474	-0.364074564	0.348512904	0.999936032	C6orf211	ARMT1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11474 (FBgn0034688). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:22071234..22073443. It has the cytological map location 58B2-58B3. Protein features are: Domain of unknown function DUF89. Its molecular function is described by: . It is involved in the biological process described with: . 4 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval fat body; lipid particle. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0027602	CG8611	-0.363836203	0.361767709	0.999936032	DDX31	DDX31	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8611 (FBgn0027602). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is X:17413267..17422145. It has the cytological map location 16A5. Protein features are: ATP-dependent RNA helicase DEAD-box, conserved site; DEAD/DEAH box helicase domain; Domain of unknown function DUF4217; Helicase superfamily 1/2, ATP-binding domain; Helicase, C-terminal; P-loop containing nucleoside triphosphate hydrolase; RNA helicase, DEAD-box type, Q motif. Its molecular function is described by: nucleic acid binding; ATP binding; ATP-dependent RNA helicase activity. It is involved in the biological process described with: RNA secondary structure unwinding. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0024555	flfl	-0.363623936	0.324089025	0.999936032	NA	PPP4R3A;PPP4R3B;PPP4R3CP	high;high;moderate	NA	NA	NA	"The gene falafel is referred to in FlyBase by the symbol Dmel\flfl (CG9351, FBgn0024555). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:13683921..13693905. It has the cytological map location 87F10-87F11. Protein features are: Armadillo-like helical; Armadillo-type fold; Domain of unknown function DUF625; PH domain-like. Its molecular function is described by: protein binding. It is involved in the biological process described with: phagocytosis; asymmetric neuroblast division; asymmetric protein localization; DNA repair; neuroblast proliferation. 30 alleles are reported. The phenotypes of these alleles manifest in: cell; mesothoracic tergum. The phenotypic classes of alleles include: some die during larval stage; fertile; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0010409	RpL18A	-0.363481015	0.282042213	0.999936032	NA	RPL18A	high	NA	NA	NA	"The gene Ribosomal protein L18A is referred to in FlyBase by the symbol Dmel\RpL18A (CG6510, FBgn0010409). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:17546406..17547462. It has the cytological map location 54C3. Protein features are: 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a; 60S ribosomal protein L18a/ L20, eukaryotes; Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A. Its molecular function is described by: RNA binding; structural constituent of ribosome. It is involved in the biological process described with: translation; cytoplasmic translation. 7 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.  "
FBgn0036232	CG14125	-0.363301923	0.282440636	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG14125 (FBgn0036232). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:11974905..11975810. It has the cytological map location 68E4. Protein features are: Chitin binding domain; PT repeat. Its molecular function is described by: chitin binding. It is involved in the biological process described with: chitin metabolic process. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed in adult male stages.
FBgn0025111	Ant2	-0.363162335	0.38516942	0.999936032	NA	SLC25A4;SLC25A6;SLC25A5;SLC25A31	moderate;high;moderate;moderate	NA	transmembrane protein	NA	"The gene Adenine nucleotide translocase 2 is referred to in FlyBase by the symbol Dmel\Ant2 (CG1683, FBgn0025111). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is X:10778954..10786907. It has the cytological map location 9E9-9F1. Protein features are: Adenine nucleotide translocator 1; Mitochondrial carrier domain; Mitochondrial carrier protein; Mitochondrial substrate/solute carrier. Its molecular function is described by: ATP:ADP antiporter activity. It is involved in the biological process described with: regulation of mitochondrial membrane permeability; ATP transport; ADP transport; transmembrane transport. 20 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; lethal - all die before end of second instar larval stage; lethal - all die before end of first instar larval stage; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed in adult male stages.  "
FBgn0038597	CG8064	-0.363142602	0.339547855	0.999936032	WDR3	WDR3	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8064 (FBgn0038597). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:18283660..18286624. It has the cytological map location 91A1. Protein features are: G-protein beta WD-40 repeat; Quinoprotein alcohol dehydrogenase-like superfamily; Small-subunit processome, Utp12; WD40 repeat; WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: snoRNA binding. It is involved in the biological process described with: cellular response to starvation; maturation of SSU-rRNA. 6 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum; ganglion mother cell; embryonic/larval neuroblast. The phenotypic classes of alleles include: increased mortality during development; phenotype; increased mortality; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0037627	CG13318	-0.363023846	0.33268447	0.999936032	NA	PLG;F9	low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13318 (FBgn0037627). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:8771246..8772691. It has the cytological map location 85B1. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain. Its molecular function is unknown. It is involved in the biological process described with: proteolysis. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed in adult female stages.  "
FBgn0038788	Sirt2	-0.362950803	0.320773363	0.999936032	SIRT2	SIRT2;SIRT3;SIRT1	high;moderate;low	NA	NA	NA	"The gene Sirtuin 2 is referred to in FlyBase by the symbol Dmel\Sirt2 (CG5085, FBgn0038788). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:20328465..20330915. It has the cytological map location 92E3. Protein features are: DHS-like NAD/FAD-binding domain; Sirtuin family; Sirtuin family, catalytic core domain; Sirtuin, class I. Its molecular function is described by: zinc ion binding; NAD-dependent histone deacetylase activity; histone deacetylase activity; NAD+ binding. It is involved in the biological process described with: dendrite morphogenesis; protein deacetylation; determination of adult lifespan; histone deacetylation. 13 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during pupal stage; lethal - all die before end of pupal stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 06-12 hour embryonic stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0030350	SelG	-0.36295041	0.305470837	0.999936032	NA	SELENOK	high	NA	transmembrane protein	NA	"The gene Selenoprotein G is referred to in FlyBase by the symbol Dmel\SelG (CG1844, FBgn0030350). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:11887284..11888240. It has the cytological map location 10F4. Protein features are: Selenoprotein SelK/SelG. Its molecular function is described by: . It is involved in the biological process described with: embryonic development via the syncytial blastoderm; endoplasmic reticulum calcium ion homeostasis; regulation of gastrulation; blastoderm segmentation; determination of adult lifespan; embryo development; calcium ion transport; immune system process; cell redox homeostasis. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0052022	CG32022	-0.362882316	0.383452158	0.999936032	NA	WRB	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32022 (FBgn0052022). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:8720280..8721272. It has the cytological map location 66D11. Protein features are: WRB/Get1 family. Its molecular function is unknown. It is involved in the biological process described with: tail-anchored membrane protein insertion into ER membrane; oogenesis. 6 alleles are reported. The phenotypes of these alleles manifest in: ring canal; nurse cell. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0261535	l(2)34Fd	-0.362760811	0.349546861	0.999936032	NA	NOL10	high	NA	NA	NA	"The gene lethal (2) 34Fd is referred to in FlyBase by the symbol Dmel\l(2)34Fd (CG7516, FBgn0261535). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:14352594..14355085. It has the cytological map location 35A1-35A2. Protein features are: NUC153; WD40 repeat; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 13 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: viable; visible; lethal - all die during larval stage; lethal; some die during pupal stage; lethal - all die before end of pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0030998	CG14195	-0.362602599	0.376194268	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14195 (FBgn0030998). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:19208694..19212082. It has the cytological map location 18B1. Protein features are: Major facilitator superfamily domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: viable; visible; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed at stages throughout the larval period, in adult male stages.  "
FBgn0035766	eco	-0.362546021	0.361503917	0.999936032	NA	ESCO1;ESCO2	high;high	NA	NA	NA	"The gene Establishment of cohesion is referred to in FlyBase by the symbol Dmel\eco (CG8598, FBgn0035766). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:7335442..7339340. It has the cytological map location 65F5. Protein features are: Acyl-CoA N-acyltransferase; GNAT domain; N-acetyltransferase ESCO, acetyl-transferase domain; N-acetyltransferase ESCO, zinc-finger. Its molecular function is described by: N-acetyltransferase activity; acetyltransferase activity. It is involved in the biological process described with: histone acetylation; mitotic sister chromatid cohesion. 10 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum; mitotic cell cycle. The phenotypic classes of alleles include: visible; mitotic cell cycle defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0034943	Fmo-1	-0.362317725	0.295095717	0.999936032	NA	FMO5;FMO2;FMO1;FMO3;FMO4	high;moderate;moderate;moderate;moderate	NA	NA	NA	"The gene Flavin-containing monooxygenase 1 is referred to in FlyBase by the symbol Dmel\Fmo-1 (CG3006, FBgn0034943). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:23962956..23964641. It has the cytological map location 60A14. Protein features are: FAD/NAD(P)-binding domain; Flavin monooxygenase FMO; Flavin monooxygenase-like. Its molecular function is described by: N,N-dimethylaniline monooxygenase activity; monooxygenase activity; flavin adenine dinucleotide binding; NADP binding. It is involved in the biological process described with: oxidation-reduction process. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; some die during pupal stage; pain response defective; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period.  "
FBgn0050016	CG30016	-0.362317725	0.295095717	0.999936032	NA	TTR	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG30016 (FBgn0050016). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:10874892..10875392. It has the cytological map location 47C5. Protein features are: Hydroxyisourate hydrolase; Transthyretin/hydroxyisourate hydrolase; Transthyretin/hydroxyisourate hydrolase, superfamily. Its molecular function is described by: hydroxyisourate hydrolase activity. It is involved in the biological process described with: purine nucleobase metabolic process. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed at stages throughout the larval period, in adult male stages.  "
FBgn0028993	scro	-0.362262777	0.379615569	0.999936032	NA	NKX2-4;NKX2-1;NKX2-3;NKX2-6;NKX2-5;NKX2-2;NKX2-8	high;high;moderate;moderate;moderate;low;low	DNA-binding with transcription factor activity(Homeobox)	NA	NA	"The gene scarecrow is referred to in FlyBase by the symbol Dmel\scro (CG17594, FBgn0028993). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 3L:24724162..24758036. Protein features are: Homeobox domain; Homeobox domain, metazoa; Homeobox domain-like; Homeobox, conserved site. Its molecular function is described by: DNA binding; sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated; dendrite morphogenesis. 8 alleles are reported. The phenotypes of these alleles manifest in: ventral multidendritic neuron vdaB; wing; dorsal multidendritic neuron ddaC; dorsal multidendritic neuron ddaD. The phenotypic classes of alleles include: neuroanatomy defective; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-18 embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0036144	GlcAT-P	-0.361776068	0.386515535	0.999936032	NA	B3GAT1;B3GAT2;B3GAT3	moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene GlcAT-P is referred to in FlyBase by the symbol Dmel\GlcAT-P (CG6207, FBgn0036144). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (2 unique). Gene sequence location is 3L:11176954..11197536. It has the cytological map location 68B1. Protein features are: Glycosyl transferase, family 43; Nucleotide-diphospho-sugar transferases. Its molecular function is described by: galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity; N-acetyllactosamine beta-1,3-glucuronosyltransferase activity; galactosyl beta-1,3 N-acetylgalactosamine beta-1,3-glucuronosyltransferase activity; asioloorosomucoid beta-1,3-glucuronosyltransferase activity. It is involved in the biological process described with: glycoprotein biosynthetic process; carbohydrate metabolic process; chondroitin sulfate proteoglycan biosynthetic process; chondroitin sulfate metabolic process; peripheral nervous system development; glycosphingolipid biosynthetic process; proteoglycan biosynthetic process. 18 alleles are reported. The phenotypes of these alleles manifest in: leg; ventral nerve cord; embryonic/larval peripheral nervous system; VUM neuron; peripheral glial cell; wing vein; wing. The phenotypic classes of alleles include: neuroanatomy defective; some die during pupal stage; lethal - all die before end of pupal stage; fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 and 12-18 hour embryonic stages, during early pupal stages, in adult female stages.  "
FBgn0031008	CG8010	-0.361691024	0.31740728	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8010 (FBgn0031008). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:19266656..19268896. It has the cytological map location 18B7. Protein features are: Protein of unknown function DUF4798. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; flight defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 06-12 hour embryonic stages, in adult female stages.  "
FBgn0038972	CG7054	-0.361460109	0.298282237	0.999936032	NA	PEBP1;PEBP4	moderate;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7054 (FBgn0038972). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:22464985..22465938. It has the cytological map location 94A16. Protein features are: Phosphatidylethanolamine-binding protein. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, during early larval stages.  "
FBgn0027506	EDTP	-0.361435679	0.348965058	0.999936032	NA	MTMR14	high	NA	NA	NA	"The gene Egg-derived tyrosine phosphatase is referred to in FlyBase by the symbol Dmel\EDTP (CG6542, FBgn0027506). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:17432173..17444938. It has the cytological map location 54B7-54B15. Protein features are: Myotubularin-like phosphatase domain; Protein-tyrosine phosphatase, active site; Protein-tyrosine phosphatase-like. Its molecular function is described by: phosphatidylinositol-3-phosphatase activity; protein tyrosine phosphatase activity. It is involved in the biological process described with: oogenesis; dephosphorylation. 21 alleles are reported. The phenotype of these alleles manifest in: ovary. The phenotypic classes of alleles include: some die during embryonic stage; fertile; lethal; viable; female semi-sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, in adult female stages.  "
FBgn0001085	fz	-0.361426849	0.389184127	0.999936032	NA	FZD1;FZD7;FZD2;FZD6;FZD3;FZD4;FZD8;FZD10;FZD9;FZD5	high;high;moderate;moderate;moderate;low;low;moderate;moderate;low	NA	transmembrane protein	GPCR	"The gene frizzled is referred to in FlyBase by the symbol Dmel\fz (CG17697, FBgn0001085). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:14274343..14368639. It has the cytological map location 70D4-70D5. Protein features are: Frizzled domain; Frizzled-7; Frizzled/Smoothened, transmembrane domain; Frizzled/secreted frizzled-related protein; GPCR, family 2-like. Its molecular function is described by: Wnt-protein binding; Wnt-activated receptor activity; transmembrane signaling receptor activity; G-protein coupled receptor activity. It is involved in the biological process described with 33 unique terms, many of which group under: macromolecule localization; regulation of biological quality; regulation of supramolecular fiber organization; female gamete generation; regulation of axon extension; cell-cell adhesion via plasma-membrane adhesion molecules; gland morphogenesis; eye photoreceptor cell fate commitment; immune system process; asymmetric protein localization; homophilic cell adhesion via plasma membrane adhesion molecules; cytoskeleton organization; localization of cell; establishment or maintenance of bipolar cell polarity; G-protein coupled receptor signaling pathway. 261 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval circulatory system; trichome field; external sensory organ precursor cell I; presumptive embryonic salivary gland; wing disc; stem cell; microtubule cytoskeleton; female organism; organelle; embryonic/first instar larval cuticle; larval tagma; arista; dorsal triple row; tarsal segment 3. The phenotypic classes of alleles include: fertile; majority die during P-stage; phenotype; viable; wild-type; cell shape defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-18 hour embryonic stages.  "
FBgn0031149	Stt3A	-0.361354699	0.322888776	0.999936032	NA	STT3A;STT3B	high;low	NA	transmembrane protein	NA	"The gene Catalytic subunit 3A of the oligosaccharyltransferase complex is referred to in FlyBase by the symbol Dmel\Stt3A (CG1518, FBgn0031149). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:21049885..21053937. It has the cytological map location 19E7. Protein features are: Oligosaccharyl transferase, STT3 subunit. Its molecular function is described by: dolichyl-diphosphooligosaccharide-protein glycotransferase activity. It is involved in the biological process described with: protein N-linked glycosylation via asparagine; chaeta development; post-translational protein modification; wing disc development. 6 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: visible; viable; flight defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0027360	Tim10	-0.361310938	0.299160083	0.999936032	TIMM10	TIMM10	high	NA	NA	NA	"The gene Translocase of inner membrane 10 is referred to in FlyBase by the symbol Dmel\Tim10 (CG9878, FBgn0027360). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:21690215..21691139. It has the cytological map location 57F8. Protein features are: Mitochondrial import inner membrane translocase subunit Tim10; Tim10-like; Tim10/FAM136A-like domain. Its molecular function is described by: protein transporter activity. It is involved in the biological process described with: negative regulation of innate immune response; defense response to Gram-negative bacterium; protein import into mitochondrial inner membrane. 7 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: visible; viable; lethal - all die during P-stage; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in stages of adults of both sexes.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0032810	CG13077	-0.361276612	0.312662439	0.999936032	NA	CYB561D2;CYB561D1	moderate;high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13077 (FBgn0032810). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:19565863..19567359. It has the cytological map location 37F1-37F2. Protein features are: Cytochrome b561/ferric reductase transmembrane. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, in stages of adults of both sexes.  "
FBgn0040234	c12.2	-0.361074979	0.335330602	0.999936032	NA	VWA8;MIR5006	high;moderate	NA	NA	NA	"The gene c12.2 is referred to in FlyBase by the symbol Dmel\c12.2 (CG12149, FBgn0040234). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:9319359..9324458. It has the cytological map location 8D7. Protein features are: AAA+ ATPase domain; ATPase, dynein-related, AAA domain; P-loop containing nucleoside triphosphate hydrolase; von Willebrand factor, type A. Its molecular function is described by: ATP binding; ATPase activity. It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0038279	Sdr	-0.360677643	0.382227072	0.999936032	NA	IGF1R;INSR;INSRR	moderate;low;low	NA	transmembrane protein	NA	"The gene Secreted decoy of InR is referred to in FlyBase by the symbol Dmel\Sdr (CG3837, FBgn0038279). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:14918628..14923083. It has the cytological map location 88D7. Protein features are: Fibronectin type III; Furin-like cysteine-rich domain; Immunoglobulin-like fold; Leucine-rich repeat domain, L domain-like; Receptor L-domain. Its molecular function is described by: insulin-like growth factor binding; ATP binding; transmembrane receptor protein tyrosine kinase activity. It is involved in the biological process described with: negative regulation of multicellular organism growth; response to starvation; protein phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway. 11 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: phenotype; visible; cell size defective; size defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed at stages throughout embryogenesis, during early pupal stages.  "
FBgn0011455	ND-SGDH	-0.360665255	0.288070179	0.999936032	NA	NDUFB5	high	NA	transmembrane protein	NA	"The gene NADH dehydrogenase (ubiquinone) SGDH subunit is referred to in FlyBase by the symbol Dmel\ND-SGDH (CG9762, FBgn0011455). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:12137496..12138584. It has the cytological map location 68F5. Protein features are: NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit. Its molecular function is described by: NADH dehydrogenase activity. It is involved in the biological process described with: response to reactive oxygen species; mitochondrial electron transport, NADH to ubiquinone; determination of adult lifespan. 7 alleles are reported. The phenotype of these alleles manifest in: adult heart. The phenotypic classes of alleles include: viable; female semi-fertile; aging defective; stress response defective; lethal; long lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0034198	CG11400	-0.360442672	0.298260274	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG11400 (FBgn0034198). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:17134129..17135345. It has the cytological map location 54A1. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed in adult male stages.
FBgn0037203	slif	-0.360328505	0.293097614	0.999936032	SLC7A1	SLC7A1;SLC7A3;SLC7A2;SLC7A4;SLC7A14	high;moderate;moderate;moderate;low	NA	transmembrane protein	NA	"The gene slimfast is referred to in FlyBase by the symbol Dmel\slif (CG11128, FBgn0037203). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3L:22881045..22893821. It has the cytological map location 80B2. Protein features are: Amino acid/polyamine transporter I; Cationic amino acid transporter, C-terminal. Its molecular function is described by: basic amino acid transmembrane transporter activity. It is involved in the biological process described with: growth; negative regulation of innate immune response; amino acid transport; defense response to Gram-negative bacterium; lipid homeostasis; amino acid transmembrane transport. 15 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval fat body; wing; wing blade posterior compartment; larva; embryonic/larval neuroblast. The phenotypic classes of alleles include: cell number defective; phenotype; increased mortality during development; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, during early pupal stages, in adult female stages.  "
FBgn0033774	CG12374	-0.360305209	0.288604352	0.999936032	NA	CPB1;CPA2;CPO;CPA3;CPB2;CPA6;CPA5;CPA1;CPA4	moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12374 (FBgn0033774). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:12762113..12763825. It has the cytological map location 49C3. Protein features are: Carboxypeptidase, activation peptide; Insect gut carboxypeptidase-like, carboxypeptidase domain; Peptidase M14, carboxypeptidase A; Protease propeptides/proteinase inhibitor I9. Its molecular function is described by: zinc ion binding; metallocarboxypeptidase activity. It is involved in the biological process described with: proteolysis. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of no expression detected.  Peak expression observed in adults stages of both sexes.  "
FBgn0032430	CG6388	-0.360282176	0.324115057	0.999936032	TRMT1	TRMT1;TRMT1L	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6388 (FBgn0032430). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:12428028..12430021. It has the cytological map location 33E4. Protein features are: S-adenosyl-L-methionine-dependent methyltransferase; tRNA methyltransferase, Trm1. Its molecular function is described by: RNA binding; tRNA (guanine-N2-)-methyltransferase activity. It is involved in the biological process described with: tRNA N2-guanine methylation. 8 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 06-18 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0033973	HPS1	-0.360240879	0.365215138	0.999936032	NA	HPS1	high	NA	NA	NA	"The gene Hermansky-Pudlak Syndrome 1 is referred to in FlyBase by the symbol Dmel\HPS1 (CG12855, FBgn0033973). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:14855429..14857502. It has the cytological map location 51C5. Protein features are: Hermansky-Pudlak syndrome 1 protein. Its molecular function is described by: . It is involved in the biological process described with: negative regulation of gene silencing by RNA; phagocytosis. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0039688	Kul	-0.360229375	0.372547088	0.999936032	NA	ADAM10	moderate	NA	transmembrane protein	NA	"The gene Kuzbanian-like is referred to in FlyBase by the symbol Dmel\Kul (CG1964, FBgn0039688). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:29725830..29735360. It has the cytological map location 99B9. Protein features are: ADAM10/ADAM17 catalytic domain; Disintegrin domain; Metallopeptidase, catalytic domain; Peptidase M12B, ADAM/reprolysin; Peptidase M12B, propeptide. Its molecular function is described by: metalloendopeptidase activity. It is involved in the biological process described with: regulation of Notch signaling pathway; membrane protein ectodomain proteolysis. 11 alleles are reported. The phenotypes of these alleles manifest in: wing; wing margin; mesothoracic tergum; wing vein; interfollicle cell; trichogen cell; wing hair. The phenotypic classes of alleles include: some die during pupal stage; partially lethal - majority die; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0026566	CG1307	-0.359755864	0.309559319	0.999936032	PTRH2	PTRH2	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1307 (FBgn0026566). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:6656030..6657442. It has the cytological map location 84A1. Protein features are: Peptidyl-tRNA hydrolase II domain; Peptidyl-tRNA hydrolase, PTH2. Its molecular function is described by: aminoacyl-tRNA hydrolase activity. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0030932	Ggt-1	-0.359676103	0.317101356	0.999936032	NA	GGT1;GGT2;GGT5;GGTLC2;GGTLC1;GGT7;GGT3P;GGT6;GGTLC3	high;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene ‘_-glutamyl transpeptidase is referred to in FlyBase by the symbol Dmel\Ggt-1 (CG6461, FBgn0030932). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:18505883..18512521. It has the cytological map location 17C1. Protein features are: Gamma-glutamyltranspeptidase; Nucleophile aminohydrolases, N-terminal. Its molecular function is described by: glutathione hydrolase activity. It is involved in the biological process described with: multicellular organism reproduction; glutathione catabolic process; response to light stimulus; glutathione metabolic process. 15 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal - majority die; behavior defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0039738	Mgat2	-0.359603234	0.379945405	0.999936032	MGAT2	MGAT2	high	NA	transmembrane protein	NA	"The gene Mgat2 is referred to in FlyBase by the symbol Dmel\Mgat2 (CG7921, FBgn0039738). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3R:30015513..30022221. It has the cytological map location 99D1-99D2. Protein features are: N-acetylglucosaminyltransferase II; Nucleotide-diphospho-sugar transferases. Its molecular function is described by: acetylglucosaminyltransferase activity; alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity. It is involved in the biological process described with: oligosaccharide biosynthetic process; protein N-linked glycosylation. 11 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages, during late pupal stages, in adult male stages.  "
FBgn0027794	Lrpprc2	-0.359528888	0.341456849	0.999936032	NA	LRPPRC	moderate	NA	NA	NA	"The gene Leucine-rich pentatricopeptide repeat containing 2 is referred to in FlyBase by the symbol Dmel\Lrpprc2 (CG14786, FBgn0027794). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:1457175..1460617. It has the cytological map location 2A4. Protein features are: Pentatricopeptide repeat; Tetratricopeptide-like helical domain. Its molecular function is described by: protein binding. It is involved in the biological process described with: regulation of rhodopsin mediated signaling pathway; regulation of mitochondrial mRNA stability; regulation of transcription from mitochondrial promoter; regulation of oxidative phosphorylation; regulation of mitochondrial translation. 16 alleles are reported. The phenotypes of these alleles manifest in: rhabdomere R3; rhabdomere R2; rhabdomere R5; rhabdomere R4; rhabdomere R1; eye photoreceptor cell; rhabdomere R6. The phenotypic classes of alleles include: partially lethal - majority live; partially lethal; increased mortality; increased mortality during development; viable; phenotype; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 06-18 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0030412	Tomosyn	-0.359512476	0.367779645	0.999936032	NA	STXBP5;STXBP5L	high;high	NA	transmembrane protein	NA	"The gene Tomosyn is referred to in FlyBase by the symbol Dmel\Tomosyn (CG17762, FBgn0030412). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (3 unique). Gene sequence location is X:12631605..12653442. It has the cytological map location 11B6-11B7. Protein features are: Lethal giant larvae homologue 2; Lethal(2) giant larvae protein; Synaptobrevin; WD40 repeat; WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: GTPase activator activity; SNARE binding; Rab GTPase binding; syntaxin binding. It is involved in the biological process described with: regulation of neuromuscular synaptic transmission; neurotransmitter secretion; synaptic vesicle exocytosis; regulation of exocytosis; synaptic vesicle priming; Golgi to plasma membrane transport; establishment or maintenance of cell polarity; long-term memory; exocytosis; regulation of protein secretion. 10 alleles are reported. The phenotypes of these alleles manifest in: intersegmental nerve; embryonic/larval hemocyte; embryonic/larval neuroblast; ganglion mother cell. The phenotypic classes of alleles include: memory defective; increased mortality; increased mortality during development; viable; phenotype; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.  "
FBgn0035666	Jon65Aii	-0.359460938	0.288488616	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Jonah 65Aii is referred to in FlyBase by the symbol Dmel\Jon65Aii (CG6580, FBgn0035666). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:6052321..6053215. It has the cytological map location 65A3-65A4. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0021874	Nle	-0.359447554	0.318469637	0.999936032	NA	NLE1	high	NA	NA	NA	"The gene Notchless is referred to in FlyBase by the symbol Dmel\Nle (CG2863, FBgn0021874). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:566366..568121. It has the cytological map location 21E2. Protein features are: G-protein beta WD-40 repeat; G-protein, beta subunit; NLE; WD40 repeat; WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: Notch binding. It is involved in the biological process described with: ribosomal large subunit assembly; Notch signaling pathway. 7 alleles are reported. The phenotypes of these alleles manifest in: microchaeta; wing hair; trichogen cell; mesothoracic tergum. The phenotypic classes of alleles include: phenotype; increased mortality during development; increased mortality; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed during early larval stages.  "
FBgn0003002	opa	-0.359194633	0.362039155	0.999936032	NA	ZIC2;ZIC1;ZIC4;ZIC3;ZIC5	high;high;moderate;moderate;moderate	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene odd paired is referred to in FlyBase by the symbol Dmel\opa (CG1133, FBgn0003002). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:4852813..4869979. It has the cytological map location 82D8-82E1. Protein features are: Tetratricopeptide-like helical domain; Zinc finger C2H2-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: transcription factor activity, sequence-specific DNA binding; RNA polymerase II distal enhancer sequence-specific DNA binding; transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding; RNA polymerase II regulatory region sequence-specific DNA binding; RNA polymerase II transcription factor activity, sequence-specific DNA binding. It is involved in the biological process described with: germ cell migration; eye-antennal disc morphogenesis; decapentaplegic signaling pathway; midgut development; positive regulation of transcription from RNA polymerase II promoter. 38 alleles are reported. The phenotypes of these alleles manifest in: imaginal precursor; proboscis; embryonic tagma; eye-antennal disc; embryonic/first instar larval cuticle; embryonic head; anatomical cluster; adult maxillary segment; embryonic/larval imaginal precursor; fat body/gonad primordium; fused midgut primordium; mechanosensory system. The phenotypic classes of alleles include: lethal - all die before end of embryonic stage; visible; lethal; pair rule phenotype; some die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0042092	CG13773	-0.358785128	0.354852765	0.999936032	NA	TWISTNB	high	Maybe TF	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13773 (FBgn0042092). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:6906666..6907844. It has the cytological map location 27C4. Its molecular function is described by: RNA polymerase I activity. It is involved in the biological process described with: transcription from RNA polymerase I promoter. 6 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: some die during pupal stage; partially lethal - majority die; viable; visible; lethal - all die during larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0037739	CG12948	-0.358509244	0.390476763	0.999936032	NA	C14orf119	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12948 (FBgn0037739). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:9746167..9747744. It has the cytological map location 85E6. Protein features are: Protein of unknown function DUF4508. Its molecular function is described by: . It is involved in the biological process described with: . 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 06-18 hour embryonic stages, during early pupal stages.  "
FBgn0037341	CG12746	-0.358395963	0.301039221	0.999936032	PPAPDC1B	PLPP5;PLPP4;PLPP1;PLPP3	high;moderate;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12746 (FBgn0037341). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:5564865..5567435. It has the cytological map location 83B2. Protein features are: Phosphatidate phosphatase PPAPDC1B; Phosphatidic acid phosphatase type 2/haloperoxidase. Its molecular function is described by: phosphatidate phosphatase activity. It is involved in the biological process described with: signal transduction; phospholipid metabolic process; dephosphorylation; phospholipid dephosphorylation. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, during early larval stages, in stages of adults of both sexes.  "
FBgn0054045	CG34045	-0.358378418	0.367310506	0.999936032	NA	LY6D	low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG34045 (FBgn0054045). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:19330889..19335188. It has the cytological map location 56D1. Its molecular function is described by: . It is involved in the biological process described with: . 5 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0010350	CdsA	-0.358376957	0.313701441	0.999936032	NA	CDS1;CDS2	high;moderate	NA	transmembrane protein	NA	"The gene CDP diglyceride synthetase is referred to in FlyBase by the symbol Dmel\CdsA (CG7962, FBgn0010350). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:8127762..8131675. It has the cytological map location 66B7. Protein features are: Phosphatidate cytidylyltransferase; Phosphatidate cytidylyltransferase, eukaryota. Its molecular function is described by: phosphatidate cytidylyltransferase activity. It is involved in the biological process described with 12 unique terms, many of which group under: response to external stimulus; developmental process; single organism signaling; regulation of cellular process; lipid localization; maintenance of location; epithelial tube morphogenesis; taxis; lipid storage; cellular process involved in reproduction in multicellular organism; growth. 23 alleles are reported. The phenotypes of these alleles manifest in: digestive system; cell component; tracheal tip cell; rhabdomere; waste bag; salivary gland; photoreceptor cell R8; pupa; tracheal system; central nervous system. The phenotypic classes of alleles include: some die during larval stage; increased mortality; phenotype; increased mortality during development; thermotaxis behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 18-24 hour embryonic stages, during late pupal stages.  "
FBgn0052264	CG32264	-0.358251333	0.329849773	0.999936032	NA	PHACTR2;PHACTR1;PHACTR3;PHACTR4	high;moderate;moderate;moderate	Maybe TF(RPEL)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32264 (FBgn0052264). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (all unique). Gene sequence location is 3L:3714826..3806459. It has the cytological map location 63E8-63F1. Protein features are: RPEL repeat; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: actin binding. It is involved in the biological process described with: actin cytoskeleton reorganization. 31 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 06-24 hour embryonic stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0024183	vig	-0.358088224	0.299526513	0.999936032	NA	SERBP1;HABP4	high;moderate	NA	NA	NA	"The gene vasa intronic gene is referred to in FlyBase by the symbol Dmel\vig (CG4170, FBgn0024183). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2L:15062931..15070316. It has the cytological map location 35B10-35C1. Protein features are: Hyaluronan/mRNA-binding protein. Its molecular function is described by: mRNA binding. It is involved in the biological process described with: RNA interference; heterochromatin organization. 12 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: suppressor of variegation; viable; female sterile; short lived; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 06-18 hour embryonic stages, during early larval stages.  "
FBgn0050339	CG30339	-0.356990389	0.305260424	0.999936032	NA	TTPAL;CLVS1;RLBP1;CLVS2;TTPA	moderate;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG30339 (FBgn0050339). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:9601431..9602901. It has the cytological map location 45F6. Protein features are: CRAL-TRIO lipid binding domain; CRAL/TRIO, N-terminal domain; Cellular retinaldehyde binding/alpha-tocopherol transport. Its molecular function is described by: transporter activity. It is involved in the biological process described with: transport. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during late larval stages.  "
FBgn0038948	PSR	-0.356973395	0.302034735	0.999936032	NA	JMJD6	high	NA	NA	NA	"The gene phosphatidylserine receptor is referred to in FlyBase by the symbol Dmel\PSR (CG5383, FBgn0038948). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:22360782..22362371. It has the cytological map location 94A6. Protein features are: JmjC domain. Its molecular function is described by: peptidyl-lysine 5-dioxygenase activity. It is involved in the biological process described with: peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine; negative regulation of JNK cascade; cell competition in a multicellular organism; negative regulation of apoptotic process. 7 alleles are reported. The phenotypes of these alleles manifest in: eye disc; male genitalia; wing; ommatidium; trichogen cell. The phenotypic classes of alleles include: viable; visible; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0259990	CG42487	-0.356880156	0.395806769	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG42487 (FBgn0259990). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:27957356..27959245. It has the cytological map location 98B6. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0038977	CG5376	-0.356767806	0.34814211	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5376 (FBgn0038977). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:22488033..22488955. It has the cytological map location 94B1. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. The phenotype of these alleles manifest in: germline cell. The phenotypic classes of alleles include: flight defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-18 embryonic stages, during late pupal stages.  "
FBgn0031653	Jon25Biii	-0.356746592	0.289162126	0.999936032	NA	C1S;F9;PROC	low;low;low	NA	NA	NA	"The gene Jonah 25Biii is referred to in FlyBase by the symbol Dmel\Jon25Biii (CG8871, FBgn0031653). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:4949941..4950767. It has the cytological map location 25B4. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, serine active site. Its molecular function is described by: endopeptidase activity; serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very low expression.  Peak expression observed at stages throughout the larval period.  "
FBgn0039051	CG17109	-0.356679597	0.297274437	0.999936032	ACY1	ACY1	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17109 (FBgn0039051). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:23095690..23097240. It has the cytological map location 94D13. Protein features are: N-acyl-L-amino-acid amidohydrolase; Peptidase M20; Peptidase M20, dimerisation domain. Its molecular function is described by: aminoacylase activity. It is involved in the biological process described with: cellular amino acid metabolic process. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0039856	CG1774	-0.356449731	0.332316863	0.999936032	ACOT9	ACOT9	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1774 (FBgn0039856). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:31592803..31594719. It has the cytological map location 100C7. Protein features are: HotDog domain; Hotdog acyl-CoA thioesterase (ACOT)-type domain. Its molecular function is described by: acyl-CoA hydrolase activity. It is involved in the biological process described with: acyl-CoA metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0000046	Act87E	-0.356193041	0.311171765	0.999936032	NA	ACTB;ACTA2;ACTC1;ACTG2;ACTA1;ACTBL2;ACTG1;POTEI;POTEJ;POTEF;ACTRT3;ACTR1B;ACTR1A;POTEE	moderate;moderate;moderate;low;moderate;moderate;low;low;moderate;low;low;low;low;low	NA	NA	NA	"The gene Actin 87E is referred to in FlyBase by the symbol Dmel\Act87E (CG18290, FBgn0000046). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:13425983..13428375. It has the cytological map location 87E11. Protein features are: Actin family; Actin, conserved site; Actin/actin-like conserved site. Its molecular function is described by: structural constituent of cytoskeleton. It is involved in the biological process described with: histone exchange; histone acetylation; cytoskeleton organization. 9 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of low expression.  Peak expression observed within 12-24 hour embryonic stages, during late pupal stages.  "
FBgn0250814	UQCR-C2	-0.35614904	0.292044081	0.999936032	NA	UQCRC2	high	NA	NA	NA	"The gene Ubiquinol-cytochrome c reductase core protein 2 is referred to in FlyBase by the symbol Dmel\UQCR-C2 (CG4169, FBgn0250814). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:16584124..16586111. It has the cytological map location 73A10. Protein features are: Metalloenzyme, LuxS/M16 peptidase-like; Peptidase M16, C-terminal; Peptidase M16, N-terminal. Its molecular function is described by: zinc ion binding; metalloendopeptidase activity; ubiquinol-cytochrome-c reductase activity. It is involved in the biological process described with: mitochondrial electron transport, ubiquinol to cytochrome c; protein processing involved in protein targeting to mitochondrion. 5 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; embryonic/larval brain; mesothoracic tergum. The phenotypic classes of alleles include: lethal; visible; viable; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0035063	CG3594	-0.355875084	0.348388317	0.999936032	NA	SYNCRIP;RBM24;HNRNPR;HNRNPA0;NCL;RBMXL3;RBM38;RBM34;SRSF2;SRSF10;RBM19	low;low;low;low;low;low;low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3594 (FBgn0035063). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:24780917..24781779. It has the cytological map location 60E1. Protein features are: RNA recognition motif domain. Its molecular function is described by: nucleic acid binding; mRNA binding. The biological processes in which it is involved are not known. 4 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0034361	mRpS28	-0.355655432	0.347997643	0.999936032	NA	MRPS28	high	NA	NA	NA	"The gene mitochondrial ribosomal protein S28 is referred to in FlyBase by the symbol Dmel\mRpS28 (CG5497, FBgn0034361). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:18614210..18615018. It has the cytological map location 55E2. Protein features are: Ribosomal protein S28, mitochondrial. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation. 7 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0001565	Hlc	-0.355584717	0.329239006	0.999936032	DDX56	DDX56	high	NA	NA	NA	"The gene Helicase is referred to in FlyBase by the symbol Dmel\Hlc (CG1666, FBgn0001565). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:21385518..21387946. It has the cytological map location 20A1. Protein features are: DEAD/DEAH box helicase domain; Helicase superfamily 1/2, ATP-binding domain; Helicase, C-terminal; P-loop containing nucleoside triphosphate hydrolase; RNA helicase, DEAD-box type, Q motif. Its molecular function is described by: nucleic acid binding; ATP binding; ATP-dependent RNA helicase activity. It is involved in the biological process described with: RNA secondary structure unwinding; rRNA processing. 23 alleles are reported. The phenotypes of these alleles manifest in: central nervous system; mesothoracic tergum; trichogen cell; peripheral nervous system; ganglion mother cell; embryonic/larval neuroblast. The phenotypic classes of alleles include: lethal - all die before end of P-stage; neuroanatomy defective; increased mortality; phenotype; increased mortality during development; visible; cell lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0051999	CG31999	-0.355340266	0.381418019	0.999936032	NA	FBLN2;FBLN1;FBLN5	high;high;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31999 (FBgn0051999). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 4:215009..227748. It has the cytological map location 102A8-102B1. Protein features are: Complement Clr-like EGF domain; EGF-like calcium-binding domain; EGF-like calcium-binding, conserved site; EGF-like domain; EGF-like, conserved site; EGF-type aspartate/asparagine hydroxylation site; Growth factor receptor cysteine-rich domain. Its molecular function is described by: calcium ion binding. The biological processes in which it is involved are not known. 6 alleles are reported. The phenotypes of these alleles manifest in: ovariole; trichogen cell. The phenotypic classes of alleles include: visible; viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 12-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0014033	Sr-CI	-0.35521024	0.338260368	0.999936032	NA	MDGA2;MDGA1	high;high	NA	transmembrane protein	NA	"The gene Scavenger receptor class C, type I is referred to in FlyBase by the symbol Dmel\Sr-CI (CG4099, FBgn0014033). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:4121702..4124153. It has the cytological map location 24D6. Protein features are: Concanavalin A-like lectin/glucanase domain; MAM domain; Somatomedin B domain; Sushi/SCR/CCP domain. Its molecular function is described by: scavenger receptor activity; polysaccharide binding. It is involved in the biological process described with: immune response; response to bacterium; defense response to Gram-negative bacterium; phagocytosis. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die during embryonic stage; lethal - all die during P-stage; viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 06-12 and 18-24 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0033902	eIF3m	-0.354961131	0.297064883	0.999936032	NA	EIF3M	high	NA	NA	NA	"The gene eukaryotic translation initiation factor 3 subunit m is referred to in FlyBase by the symbol Dmel\eIF3m (CG8309, FBgn0033902). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:14163066..14164825. It has the cytological map location 50E1. Protein features are: Armadillo-like helical; Eukaryotic translation initiation factor 3 subunit M; Proteasome component (PCI) domain; Winged helix-turn-helix DNA-binding domain. Its molecular function is described by: caspase binding; translation initiation factor binding; translation initiation factor activity. It is involved in the biological process described with: neuron projection morphogenesis; protein secretion; Golgi organization; translation; positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis; cytoplasmic translational initiation; activation of cysteine-type endopeptidase activity; sperm individualization. 13 alleles are reported. The phenotypes of these alleles manifest in: wing; investment cone; cystic bulge. The phenotypic classes of alleles include: lethal - all die before end of first instar larval stage; visible; male sterile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0010217	ATPsynbeta	-0.354919061	0.292149274	0.999936032	NA	ATP5B	high	NA	transmembrane protein	NA	"The gene ATP synthase, ‘_ subunit is referred to in FlyBase by the symbol Dmel\ATPsyn‘_ (CG11154, FBgn0010217). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 4:1031484..1034917. It has the cytological map location 102F6. Protein features are: AAA+ ATPase domain; ATP synthase, F1 complex, beta subunit; ATPase, F1/V1 complex, beta/alpha subunit, C-terminal; ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain; ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain; ATPase, alpha/beta subunit, nucleotide-binding domain, active site; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: proton-transporting ATPase activity, rotational mechanism; proton-transporting ATP synthase activity, rotational mechanism; ATP binding. It is involved in the biological process described with: lateral inhibition; proton transport; ATP synthesis coupled proton transport; regulation of glucose metabolic process. 12 alleles are reported. The phenotypes of these alleles manifest in: adult thorax; chaeta; wing. The phenotypic classes of alleles include: increased mortality during development; phenotype; lethal; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0086532	Spt-I	-0.354762587	0.306546077	0.999936032	NA	SPTLC1	high	NA	transmembrane protein	NA	"The gene Serine palmitoyltransferase subunit I is referred to in FlyBase by the symbol Dmel\Spt-I (CG4016, FBgn0086532). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:13168498..13170744. It has the cytological map location 49F4. Protein features are: Aminotransferase, class I/classII; Pyridoxal phosphate-dependent transferase; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; Pyridoxal phosphate-dependent transferase, subdomain 2. Its molecular function is described by: pyridoxal phosphate binding; catalytic activity. It is involved in the biological process described with: positive regulation of sphingolipid biosynthetic process. 12 alleles are reported. The phenotypes of these alleles manifest in: dendritic arborizing neuron; trichogen cell; sensory neuron. The phenotypic classes of alleles include: lethal - all die before end of larval stage; increased mortality; stress response defective; phenotype; visible; neuroanatomy defective; some die during larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0052557	CG32557	-0.354743082	0.305070044	0.999936032	NA	HEPHL1;CP;HEPH	low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32557 (FBgn0052557). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:17852958..17856129. It has the cytological map location 16E1-16E2. Protein features are: Cupredoxin; Multicopper oxidase, copper-binding site; Multicopper oxidase, type 1; Multicopper oxidase, type 2; Multicopper oxidase, type 3. Its molecular function is described by: ferroxidase activity; copper ion binding; iron ion transmembrane transporter activity. It is involved in the biological process described with: iron assimilation by reduction and transport; oxidation-reduction process; iron ion transport. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the larval period.  "
FBgn0039417	CG6073	-0.354614846	0.353242393	0.999936032	FAM203A	HGH1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6073 (FBgn0039417). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:26187018..26188807. It has the cytological map location 97A4. Protein features are: Armadillo-like helical; Armadillo-type fold; Protein HGH1 C-terminal; Protein HGH1 N-terminal. Its molecular function is described by: . The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0039336	CG4553	-0.354602052	0.383638477	0.999936032	NA	NGRN	high	DNA-binding with transcription factor activity	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4553 (FBgn0039336). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:25475636..25476915. It has the cytological map location 96E1. Protein features are: Neugrin/Rrg9. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0039830	ATPsynC	-0.353856157	0.293144743	0.999936032	NA	ATP5G2;ATP5G1;ATP5G3	high;moderate;moderate	NA	transmembrane protein	NA	"The gene ATP synthase, subunit C is referred to in FlyBase by the symbol Dmel\ATPsynC (CG1746, FBgn0039830). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (2 unique). Gene sequence location is 3R:31216145..31219630. It has the cytological map location 100B7. Protein features are: ATP synthase, F0 complex, subunit C; ATP synthase, F0 complex, subunit C, DCCD-binding site; V-ATPase proteolipid subunit C-like domain. Its molecular function is described by: proton-transporting ATP synthase activity, rotational mechanism. It is involved in the biological process described with: ATP synthesis coupled proton transport; ATP hydrolysis coupled proton transport; proton transport. 9 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0085421	Epac	-0.353811546	0.361800914	0.999936032	NA	RAPGEF4;RAPGEF3;RAPGEF5;RAPGEFL1	high;moderate;moderate;moderate	NA	NA	NA	"The gene Exchange protein directly activated by cAMP is referred to in FlyBase by the symbol Dmel\Epac (CG34392, FBgn0085421). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 2R:6759715..6798941. It has the cytological map location 42D1. Protein features are: Cyclic nucleotide-binding domain; Cyclic nucleotide-binding-like; DEP domain; Ras guanine nucleotide exchange factor domain; Ras guanine-nucleotide exchange factor, conserved site; Ras guanine-nucleotide exchange factors catalytic domain; Ras-associating (RA) domain; Ras-like guanine nucleotide exchange factor, N-terminal; RmlC-like jelly roll fold; Ubiquitin-related domain; Winged helix-turn-helix DNA-binding domain. Its molecular function is described by: guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: regulation of Rap protein signal transduction. 17 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages, at stages throughout the pupal period.  "
FBgn0035718	CG14820	-0.353707841	0.287762271	0.999936032	CPO	CPB1;CPO;CPA3;CPB2;CPA6;CPA2;CPA5;CPA1;CPA4	moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14820 (FBgn0035718). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:6932926..6934824. It has the cytological map location 65D3. Protein features are: Carboxypeptidase, activation peptide; Insect gut carboxypeptidase-like, carboxypeptidase domain; Peptidase M14, carboxypeptidase A; Protease propeptides/proteinase inhibitor I9. Its molecular function is described by: zinc ion binding; metallocarboxypeptidase activity. It is involved in the biological process described with: proteolysis. 2 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, during late larval stages.  "
FBgn0010359	gammaTry	-0.35366994	0.298840503	0.999936032	NA	PRSS36;PRSS53;PRSS1;PRSS3	low;low;low;low	NA	NA	NA	"The gene ‘_Trypsin is referred to in FlyBase by the symbol Dmel\‘_Try (CG30028, FBgn0010359). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:11349061..11349870. It has the cytological map location 47F4. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is unknown. It is involved in the biological process described with: proteolysis. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0039111	PTPMT1	-0.353627231	0.336870132	0.999936032	NA	PTPMT1	high	NA	NA	NA	"The gene Protein tyrosine phosphatase, mitochondrial 1 is referred to in FlyBase by the symbol Dmel\PTPMT1 (CG10371, FBgn0039111). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:23758339..23759606. It has the cytological map location 95B1. Protein features are: Dual specificity phosphatase; Dual specificity phosphatase, catalytic domain; Dual specificity protein phosphatase domain; Protein-tyrosine phosphatase, active site; Protein-tyrosine phosphatase-like; Tyrosine specific protein phosphatases domain. Its molecular function is described by: protein tyrosine/serine/threonine phosphatase activity; protein tyrosine phosphatase activity; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. It is involved in the biological process described with: dephosphorylation; protein dephosphorylation. 4 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval neuroblast; ganglion mother cell; trichogen cell. The phenotypic classes of alleles include: lethal; viable; flight defective; female semi-sterile; visible; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 12-18 embryonic stages.  "
FBgn0032167	CG5853	-0.353551132	0.300306441	0.999936032	NA	ABCG1;ABCG4;ABCG2;ABCG8	high;moderate;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5853 (FBgn0032167). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:9940773..9947648. It has the cytological map location 30F1. Protein features are: AAA+ ATPase domain; ABC transporter, conserved site; ABC transporter-like; ABC-2 type transporter; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: sterol-transporting ATPase activity; ATP binding; cholesterol transporter activity. It is involved in the biological process described with: phagocytosis. 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during early pupal stages.  "
FBgn0266168	CR44874	-0.353426976	0.297891	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44874 (FBgn0266168). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2L:10051362..10052289. It has the cytological map location 31A1. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. The phenotypic class of allele includes: viable.
FBgn0031289	CG13950	-0.353117937	0.394264096	0.999936032	NA	LGALSL	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13950 (FBgn0031289). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:860197..861806. It has the cytological map location 21E2. Protein features are: Concanavalin A-like lectin/glucanase domain; Galectin, carbohydrate recognition domain. Its molecular function is described by: carbohydrate binding. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0033372	CG13742	-0.352540326	0.398482153	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13742 (FBgn0033372). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 2R:9084598..9087808. It has the cytological map location 45A1. Its molecular function is unknown. The biological processes in which it is involved are not known. 12 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0035600	Cyt-c1	-0.352448565	0.296570612	0.999936032	NA	CYC1	high	NA	NA	NA	"The gene Cytochrome c1 is referred to in FlyBase by the symbol Dmel\Cyt-c1 (CG4769, FBgn0035600). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:5360211..5362798. It has the cytological map location 64C13. Protein features are: Cytochrome c-like domain; Cytochrome c1; Cytochrome c1, transmembrane anchor, C-terminal. Its molecular function is described by: electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity; heme binding; electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity. It is involved in the biological process described with: mitochondrial electron transport, ubiquinol to cytochrome c; mitochondrial ATP synthesis coupled proton transport. 8 alleles are reported. The phenotypes of these alleles manifest in: adult heart; trichogen cell. The phenotypic classes of alleles include: lethal - all die during larval stage; developmental rate defective; viable; visible; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0052409	CG32409	-0.352371403	0.333625352	0.999936032	NA	RRS1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32409 (FBgn0052409). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:5899528..5900936. It has the cytological map location 64F4. Protein features are: Ribosomal biogenesis regulatory protein. Its molecular function is unknown. It is involved in the biological process described with: ribosomal large subunit biogenesis; ribosomal large subunit export from nucleus; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). 3 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0039299	CG11854	-0.352363264	0.401603579	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG11854 (FBgn0039299). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:25242020..25243262. It has the cytological map location 96C7. Protein features are: Haemolymph juvenile hormone binding. Its molecular function is unknown. It is involved in the biological process described with: circadian rhythm; multicellular organism reproduction. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed during late larval stages.
FBgn0265182	CG44247	-0.352363264	0.401603579	0.999936032	NA	NPDC1;CREB5;ATF7;ATF2;FOSL2;FOS;FOSL1;NPDC1	high;moderate;moderate;moderate;low;low;low;low	DNA-binding with transcription factor activity	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG44247 (FBgn0265182). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:24876691..24881221. It has the cytological map location 60E4-60E5. Protein features are: Neural proliferation differentiation control-1. Its molecular function is described by: . It is involved in the biological process described with: . 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable.
FBgn0040227	eIF3d1	-0.352143411	0.306519683	0.999936032	NA	EIF3D	high	NA	NA	NA	"The gene eukaryotic translation initiation factor 3 subunit d1 is referred to in FlyBase by the symbol Dmel\eIF3d1 (CG10161, FBgn0040227). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:23680039..23682317. It has the cytological map location 95A7. Protein features are: Eukaryotic translation initiation factor 3 subunit D. Its molecular function is described by: protein binding; translation initiation factor activity. It is involved in the biological process described with: translational initiation; regulation of translational initiation. 7 alleles are reported. The phenotype of these alleles manifest in: eye. The phenotypic classes of alleles include: visible; long lived; wild-type. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages.  "
FBgn0261119	Prp19	-0.352064341	0.331547487	0.999936032	NA	PRPF19	high	NA	NA	NA	"The gene Pre-RNA processing factor 19 is referred to in FlyBase by the symbol Dmel\Prp19 (CG5519, FBgn0261119). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:18447361..18451041. It has the cytological map location 55C9-55D2. Protein features are: G-protein beta WD-40 repeat; Pre-mRNA-splicing factor 19; Quinoprotein alcohol dehydrogenase-like superfamily; U box domain; WD40 repeat; WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: ubiquitin-protein transferase activity. It is involved in the biological process described with: mRNA splicing, via spliceosome; regulation of alternative mRNA splicing, via spliceosome; protein ubiquitination; positive regulation of ERK1 and ERK2 cascade; positive regulation of Ras protein signal transduction; chromatin organization; generation of catalytic spliceosome for first transesterification step. 12 alleles are reported. The phenotypes of these alleles manifest in: nucleolus; nurse cell; chromatin. The phenotypic classes of alleles include: female sterile; lethal; viable; pain response defective; long lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0019644	ATPsynB	-0.35147861	0.297576689	0.999936032	NA	ATP5F1	high	NA	NA	NA	"The gene ATP synthase, subunit B is referred to in FlyBase by the symbol Dmel\ATPsynB (CG8189, FBgn0019644). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:9729999..9731224. It has the cytological map location 67C5. Protein features are: ATP synthase, F0 complex, subunit B; ATP synthase, F0 complex, subunit B/MI25. Its molecular function is described by: proton-transporting ATP synthase activity, rotational mechanism. It is involved in the biological process described with: proton transport; phagocytosis; ATP synthesis coupled proton transport. 5 alleles are reported. The phenotypes of these alleles manifest in: sarcomere; Z disc; trichogen cell; mitochondrion; mesothoracic tergum; spermatid; vacuole. The phenotypic classes of alleles include: increased mortality; phenotype; increased mortality during development; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed during late pupal stages.  "
FBgn0014863	Mlp84B	-0.351456716	0.31374056	0.999936032	NA	CSRP3;CSRP1;CSRP2	high;moderate;moderate	NA	NA	NA	"The gene Muscle LIM protein at 84B is referred to in FlyBase by the symbol Dmel\Mlp84B (CG1019, FBgn0014863). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:7112850..7117732. It has the cytological map location 84C1. Protein features are: Zinc finger, LIM-type. Its molecular function is described by: structural constituent of muscle. It is involved in the biological process described with: muscle tissue development; sarcomere organization; regulation of establishment of planar polarity. 17 alleles are reported. The phenotypes of these alleles manifest in: visceral muscle fiber; trichogen cell; filamentous actin; mesothoracic tergum. The phenotypic classes of alleles include: lethal; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0014455	Ahcy	-0.351218149	0.304614721	0.999936032	NA	AHCY;AHCYL1;AHCYL2	high;low;low	NA	NA	NA	"The gene Adenosylhomocysteinase is referred to in FlyBase by the symbol Dmel\Ahcy (CG11654, FBgn0014455). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:15450261..15453167. It has the cytological map location 13C3. Protein features are: Adenosylhomocysteinase; Adenosylhomocysteinase-like; NAD(P)-binding domain; S-adenosyl-L-homocysteine hydrolase, NAD binding domain; S-adenosyl-L-homocysteine hydrolase, conserved site. Its molecular function is described by: NAD binding; adenosylhomocysteinase activity. It is involved in the biological process described with: S-adenosylhomocysteine catabolic process; S-adenosylmethionine cycle; one-carbon metabolic process. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0032646	mEFTs	-0.351185535	0.34315506	0.999936032	NA	TSFM	high	NA	NA	NA	"The gene mitochondrial translation elongation factor Ts is referred to in FlyBase by the symbol Dmel\mEFTs (CG6412, FBgn0032646). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:17499268..17501106. It has the cytological map location 36C10. Protein features are: Translation elongation factor EFTs/EF1B; Translation elongation factor EFTs/EF1B, dimerisation; Translation elongation factor Ts, conserved site; UBA-like. Its molecular function is described by: translation elongation factor activity. It is involved in the biological process described with: translational elongation; mitochondrial translational elongation. 8 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: viable; lethal - all die during P-stage; visible; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed in adult male stages.  "
FBgn0015872	Drip	-0.351147964	0.328724948	0.999936032	NA	AQP4;AQP2;AQP1;AQP5;MIP;AQP8;AQP6;AQP3;AQP9;AQP7	high;moderate;moderate;moderate;moderate;moderate;low;low;low;low	NA	transmembrane protein	NA	"The gene Drip is referred to in FlyBase by the symbol Dmel\Drip (CG9023, FBgn0015872). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (6 unique). Gene sequence location is 2R:11411203..11429645. It has the cytological map location 47F11. Protein features are: Aquaporin transporter; Aquaporin-like; Major intrinsic protein; Major intrinsic protein, conserved site. Its molecular function is described by: water channel activity. It is involved in the biological process described with: water homeostasis; renal system process; regulation of oviposition; transmembrane transport; ion transmembrane transport; water transport. 11 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal; fertile; lethal - all die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult male stages.  "
FBgn0010282	TfIIFalpha	-0.350855167	0.342269454	0.999936032	NA	GTF2F1	high	DNA-binding with transcription factor activity	NA	NA	"The gene Transcription factor IIF‘± is referred to in FlyBase by the symbol Dmel\TfIIF‘± (CG10281, FBgn0010282). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:6380467..6382604. It has the cytological map location 83E5. Protein features are: Transcription Factor IIF, Rap30/Rap74, interaction; Transcription initiation factor IIF, alpha subunit; Winged helix-turn-helix DNA-binding domain. Its molecular function is described by: TFIIF-class transcription factor binding; DNA binding. It is involved in the biological process described with: transcription initiation from RNA polymerase II promoter; positive regulation of transcription elongation from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter. 6 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; embryonic/larval neuroblast. The phenotypic classes of alleles include: viable; lethal; lethal - all die during embryonic stage; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0031533	CG2772	-0.350792944	0.287406813	0.999936032	NA	LIPK;LIPJ;LIPF;LIPN;LIPA;LIPM	moderate;high;moderate;high;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG2772 (FBgn0031533). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:3445992..3447589. It has the cytological map location 23F3. Protein features are: Alpha/Beta hydrolase fold; Lipase, eukaryotic; Partial AB-hydrolase lipase domain. Its molecular function is described by: hydrolase activity, acting on ester bonds. It is involved in the biological process described with: lipid metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period.  "
FBgn0035541	CG15019	-0.350575224	0.306792758	0.999936032	NA	LLPH	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15019 (FBgn0035541). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:4405127..4406059. It has the cytological map location 64B4. Protein features are: Learning associated protein 18-like. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0029849	Efr	-0.350206273	0.307431519	0.999936032	SLC35B4	SLC35B4	high	NA	transmembrane protein	NA	"The gene ER GDP-fucose transporter is referred to in FlyBase by the symbol Dmel\Efr (CG3774, FBgn0029849). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:6219957..6222719. It has the cytological map location 5E1. Protein features are: UAA transporter. Its molecular function is described by: UDP-xylose transmembrane transporter activity; GDP-fucose transmembrane transporter activity; UDP-N-acetylglucosamine transmembrane transporter activity. It is involved in the biological process described with: GDP-fucose transport; transmembrane transport; UDP-N-acetylglucosamine transport; heparan sulfate proteoglycan biosynthetic process; protein O-linked fucosylation; UDP-xylose transport; GDP-fucose import into endoplasmic reticulum lumen. 12 alleles are reported. The phenotype of these alleles manifest in: wing vein L5. The phenotypic classes of alleles include: some die during pupal stage; partially lethal - majority die; viable; visible; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0037708	CG9386	-0.350161191	0.378390515	0.999936032	TRMT44	TRMT44	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9386 (FBgn0037708). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:9553696..9555408. It has the cytological map location 85D24. Protein features are: tRNA (uracil-O(2)-)-methyltransferase. Its molecular function is described by: tRNA (uracil) methyltransferase activity. It is involved in the biological process described with: tRNA methylation. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 06-24 hour embryonic stages, during early pupal stages, in adult female stages.  "
FBgn0037001	ND-39	-0.350109445	0.303433917	0.999936032	NA	NDUFA9	high	NA	NA	NA	"The gene NADH dehydrogenase (ubiquinone) 39 kDa subunit is referred to in FlyBase by the symbol Dmel\ND-39 (CG6020, FBgn0037001). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:20492082..20497084. It has the cytological map location 77C6. Protein features are: NAD(P)-binding domain; NAD-dependent epimerase/dehydratase. Its molecular function is described by: NADH dehydrogenase activity; coenzyme binding. It is involved in the biological process described with: ubiquinone-6 biosynthetic process; mitochondrial electron transport, NADH to ubiquinone. 11 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum. The phenotypic classes of alleles include: lethal - all die during larval stage; developmental rate defective; lethal; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0016684	NaPi-T	-0.350078898	0.390477104	0.999936032	NA	SLC17A5;SLC17A4;SLC17A3;SLC17A2;SLC17A1	low;low;low;low;low	NA	transmembrane protein	NA	"The gene Na<sup>+</sup>-dependent inorganic phosphate cotransporter is referred to in FlyBase by the symbol Dmel\NaPi-T (CG10207, FBgn0016684). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:14842720..14845874. It has the cytological map location 51C5. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain; Na-dependent inorganic phosphate cotransporter. Its molecular function is described by: phosphate ion transmembrane transporter activity; transmembrane transporter activity. It is involved in the biological process described with: anion transport; phosphate ion transmembrane transport; transmembrane transport. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed during early larval stages, in adult male stages.  "
FBgn0263344	CR43425	-0.349924454	0.261228041	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR43425 (FBgn0263344). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 4:867824..871426. It has the cytological map location 102E5. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available.
FBgn0029863	CG3823	-0.349920697	0.351030469	0.999936032	NA	TTPAL;CLVS1;RLBP1;CLVS2;TTPA	moderate;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3823 (FBgn0029863). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:6303975..6306745. It has the cytological map location 5E7-5E8. Protein features are: CRAL-TRIO lipid binding domain; CRAL/TRIO, N-terminal domain; Cellular retinaldehyde binding/alpha-tocopherol transport. Its molecular function is described by: transporter activity. It is involved in the biological process described with: transport. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the pupal period.  "
FBgn0036906	CG14102	-0.349667813	0.397507295	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14102 (FBgn0036906). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:19798975..19801291. It has the cytological map location 76C6. Protein features are: Leucine-rich repeat domain, L domain-like. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0036993	CG5910	-0.349264123	0.309902622	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5910 (FBgn0036993). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:20442419..20450580. It has the cytological map location 77C3. Its molecular function is unknown. The biological processes in which it is involved are not known. 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, during early pupal stages, in adult male stages.  "
FBgn0032705	Grip71	-0.349117999	0.375184065	0.999936032	NA	NEDD1	high	NA	NA	NA	"The gene Grip71 is referred to in FlyBase by the symbol Dmel\Grip71 (CG10346, FBgn0032705). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:18708846..18711297. It has the cytological map location 37A1. Protein features are: WD40 repeat; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: gamma-tubulin binding. It is involved in the biological process described with: regulation of cell cycle; spindle assembly involved in female meiosis I; mitotic cell cycle; centrosome cycle. 6 alleles are reported. The phenotypes of these alleles manifest in: neuroblast; spindle. The phenotypic classes of alleles include: female sterile; mitotic cell cycle defective; lethal - all die before end of embryonic stage; viable; some die during embryonic stage; male fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0031249	CG11911	-0.349097173	0.287259787	0.999936032	NA	PRSS36;PRSS53;AZU1;PRTN3	low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11911 (FBgn0031249). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:320279..321248. It has the cytological map location 21B8. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0036018	CG3335	-0.349087285	0.384620656	0.999936032	RBM19	RBM19	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3335 (FBgn0036018). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:9624237..9627321. It has the cytological map location 67C2. Protein features are: Probable RNA-binding protein 19, RNA recognition motif 1; Probable RNA-binding protein 19, RNA recognition motif 3; Probable RNA-binding protein 19, RNA recognition motif 4; Probable RNA-binding protein 19, RNA recognition motif 5; Probable RNA-binding protein 19, RNA recognition motif 6; RNA recognition motif domain. Its molecular function is described by: mRNA binding; nucleic acid binding; helicase activity. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, in adult female stages.  "
FBgn0053514	CG33514	-0.348994717	0.302380505	0.999936032	NA	TTPAL;CLVS1;RLBP1;CLVS2;TTPA	moderate;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG33514 (FBgn0053514). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:4365434..4366671. It has the cytological map location 64B2. Protein features are: CRAL-TRIO lipid binding domain; CRAL/TRIO, N-terminal domain; Cellular retinaldehyde binding/alpha-tocopherol transport. Its molecular function is described by: transporter activity. It is involved in the biological process described with: transport. 2 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval neuroblast; ganglion mother cell. The phenotypic classes of alleles include: some die during pupal stage; increased mortality; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in stages of adults of both sexes.  "
FBgn0031359	Rim2	-0.348990242	0.329503128	0.999936032	NA	SLC25A36;SLC25A33	high;moderate	NA	NA	NA	"The gene Replication in mitochondria 2 is referred to in FlyBase by the symbol Dmel\Rim2 (CG18317, FBgn0031359). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 2L:1716244..1724388. It has the cytological map location 22B1. Protein features are: Mitochondrial carrier UCP-like; Mitochondrial carrier domain; Mitochondrial substrate/solute carrier. Its molecular function is described by: pyrimidine nucleotide transmembrane transporter activity. It is involved in the biological process described with: transcription from mitochondrial promoter; mitochondrial pyrimidine nucleotide import; deoxynucleotide transport; mitochondrial transport; mitochondrion organization; locomotion; mitochondrion distribution; cellular respiration. 13 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; long lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed in adult male stages.  "
FBgn0037615	CG11760	-0.348686197	0.234385056	0.999936032	NA	TMEM216;TMEM80	high;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11760 (FBgn0037615). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:8719198..8721320. It has the cytological map location 85A9. Protein features are: Uncharacterised protein family, transmembrane-17. Its molecular function is described by: . It is involved in the biological process described with: cilium assembly. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during late pupal stages.  "
FBgn0013771	Cyp6a9	-0.348634792	0.313017097	0.999936032	TBXAS1	TBXAS1;CYP3A43;CYP3A4;CYP3A5;CYP3A7-CYP3A51P;CYP3A7	moderate;moderate;moderate;moderate;low;low	NA	transmembrane protein	NA	"The gene Cytochrome P450-6a9 is referred to in FlyBase by the symbol Dmel\Cyp6a9 (CG10246, FBgn0013771). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:14879356..14881372. It has the cytological map location 51D1. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Its molecular function is described by: heme binding; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; electron carrier activity; oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0027348	bgm	-0.348579988	0.330865955	0.999936032	NA	ACSBG2;ACSBG1	high;moderate	NA	NA	NA	"The gene bubblegum is referred to in FlyBase by the symbol Dmel\bgm (CG4501, FBgn0027348). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:14013004..14019328. It has the cytological map location 34F1. Protein features are: AMP-dependent synthetase/ligase. Its molecular function is described by: long-chain fatty acid-CoA ligase activity. It is involved in the biological process described with: sleep; fatty acid metabolic process; neuron cellular homeostasis; response to endoplasmic reticulum stress; long-chain fatty acid metabolic process. 18 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval gut; lamina; optic lobe; retina; ommatidium; basement membrane; lamina monopolar neuron; mesothoracic tergum. The phenotypic classes of alleles include: increased mortality; increased mortality during development; phenotype; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0034380	Vps51	-0.348206871	0.402399043	0.999936032	NA	VPS51	high	NA	NA	NA	"The gene Vacuolar protein sorting 51 is referred to in FlyBase by the symbol Dmel\Vps51 (CG15087, FBgn0034380). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:18708152..18710865. It has the cytological map location 55E9. Protein features are: Cullin repeat-like-containing domain. Its molecular function is described by: . It is involved in the biological process described with: endocytic recycling; Golgi organization; Golgi vesicle transport; retrograde transport, endosome to Golgi. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0034214	CG6550	-0.347826687	0.354316883	0.999936032	CDKAL1	CDKAL1	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6550 (FBgn0034214). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:17425670..17427511. It has the cytological map location 54B7. Protein features are: Elongator protein 3/MiaB/NifB; Methylthiotransferase; Methylthiotransferase, N-terminal; Methylthiotransferase, conserved site; MiaB-like tRNA modifying enzyme, archaeal-type; Radical SAM; Radical SAM, alpha/beta horseshoe; TRAM domain. Its molecular function is described by: N6-threonylcarbomyladenosine methylthiotransferase activity; 4 iron, 4 sulfur cluster binding. It is involved in the biological process described with: tRNA modification. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0036242	CG6793	-0.347691829	0.319979686	0.999936032	NA	SYCP1	low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG6793 (FBgn0036242). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:12042387..12044217. It has the cytological map location 68F1. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed during early pupal stages.
FBgn0265189	sud1	-0.347648226	0.395277324	0.999936032	NA	OGFOD1;PIGS;OGFOD1	moderate;high;moderate	NA	transmembrane protein	NA	"The gene sudestada1 is referred to in FlyBase by the symbol Dmel\sud1 (CG44254, FBgn0265189). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:24915840..24917864. It has the cytological map location 96B6. Protein features are: Oxoglutarate/iron-dependent dioxygenase; Oxoglutarate/iron-dependent oxygenase, C-terminal degradation domain; Prolyl 4-hydroxylase, alpha subunit. Its molecular function is described by: peptidyl-proline dioxygenase activity; iron ion binding; L-ascorbic acid binding. It is involved in the biological process described with: regulation of translational termination; peptidyl-proline hydroxylation; oxidation-reduction process; protein hydroxylation; regulation of translation. 4 alleles are reported. The phenotypes of these alleles manifest in: 2nd posterior cell; mesothoracic tergum; trichogen cell; embryonic/larval fat body. The phenotypic classes of alleles include: some die during larval stage; partially lethal; visible; phenotype; increased mortality during development."
FBgn0039827	CG1544	-0.347621636	0.385168342	0.999936032	DHTKD1	DHTKD1;OGDH;OGDHL	high;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1544 (FBgn0039827). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:31196916..31203722. It has the cytological map location 100B5. Protein features are: 2-oxoglutarate dehydrogenase E1 component; Dehydrogenase, E1 component; Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal; Thiamin diphosphate-binding fold; Transketolase-like, pyrimidine-binding domain. Its molecular function is described by: oxoglutarate dehydrogenase (succinyl-transferring) activity; thiamine pyrophosphate binding. It is involved in the biological process described with: generation of precursor metabolites and energy; tricarboxylic acid cycle. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during early larval stages.  "
FBgn0037305	CG12173	-0.34728616	0.342349819	0.999936032	ENOPH1	ENOPH1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12173 (FBgn0037305). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:5255444..5256681. It has the cytological map location 82F7. Protein features are: Enolase-phosphatase E1; Enolase-phosphatase E1, eukaryotes; HAD hydrolase, subfamily IA; HAD-like domain. Its molecular function is described by: magnesium ion binding; acireductone synthase activity. It is involved in the biological process described with: L-methionine salvage from methylthioadenosine. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: mating behavior defective; flightless; short lived; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.  "
FBgn0003863	alphaTry	-0.347201607	0.301052357	0.999936032	NA	PRSS36;PRSS53;PRSS45;PRSS8;PRSS27;PRSS22;TPSG1;PRSS33;PRSS38;KLK1;KLK2;PRSS48;CMA1;PRSS1;PRSS3	low;low;low;low;low;low;low;low;low;low;low;low;low;low;low	NA	NA	NA	"The gene ‘±Trypsin is referred to in FlyBase by the symbol Dmel\‘±Try (CG18444, FBgn0003863). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:11344260..11345119. It has the cytological map location 47F4. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of extremely low expression.  Peak expression observed in adults stages of both sexes.  "
FBgn0029924	CG4586	-0.347086902	0.343982785	0.999936032	NA	ACOX1;ACOX2	moderate;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4586 (FBgn0029924). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:6969918..6972265. It has the cytological map location 6E4. Protein features are: Acyl-CoA dehydrogenase/oxidase C-terminal; Acyl-CoA dehydrogenase/oxidase, N-terminal; Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain; Acyl-CoA oxidase; Acyl-CoA oxidase, C-terminal; Acyl-CoA oxidase/dehydrogenase, central domain; Acyl-coenzyme A oxidase, N-terminal. Its molecular function is described by: flavin adenine dinucleotide binding; acyl-CoA dehydrogenase activity; FAD binding; acyl-CoA oxidase activity. It is involved in the biological process described with: fatty acid beta-oxidation; fatty acid beta-oxidation using acyl-CoA dehydrogenase. 5 alleles are reported. The phenotypes of these alleles manifest in: lipid particle; embryonic/larval fat body. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0250874	ttm50	-0.347082151	0.327172141	0.999936032	NA	TIMM50	high	NA	NA	NA	"The gene tiny tim 50 is referred to in FlyBase by the symbol Dmel\ttm50 (CG2713, FBgn0250874). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:2730077..2732190. It has the cytological map location 3B3. Protein features are: FCP1 homology domain; HAD-like domain; Mitochondrial import inner membrane translocase subunit Tim50. Its molecular function is described by: phosphoprotein phosphatase activity; protein tyrosine phosphatase activity; protein serine/threonine phosphatase activity. It is involved in the biological process described with: mitochondrial membrane organization; protein dephosphorylation; mitochondrion organization; protein import into mitochondrial matrix. 10 alleles are reported. The phenotypes of these alleles manifest in: dendrite; abdominal dorsal multidendritic neuron ddaE; mitochondrion; eye; imaginal disc; abdominal dorsal multidendritic neuron ddaC; macrochaeta; abdominal dorsal multidendritic neuron ddaA. The phenotypic classes of alleles include: cell size defective; phenotype; increased mortality during development; cell cycle defective; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0002524	lace	-0.346823338	0.317553184	0.999936032	NA	SPTLC2;SPTLC3	high;moderate	NA	NA	NA	"The gene lace is referred to in FlyBase by the symbol Dmel\lace (CG4162, FBgn0002524). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:15499127..15505018. It has the cytological map location 35D2. Protein features are: Aminotransferase, class I/classII; Aminotransferase, class-II, pyridoxal-phosphate binding site; Pyridoxal phosphate-dependent transferase; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; Pyridoxal phosphate-dependent transferase, subdomain 2. Its molecular function is described by: pyridoxal phosphate binding; serine C-palmitoyltransferase activity. It is involved in the biological process described with: regulation of cellular protein localization; sphingolipid biosynthetic process; regulation of Notch signaling pathway; regulation of growth; regulation of Wnt signaling pathway; imaginal disc development. 37 alleles are reported. The phenotypes of these alleles manifest in: lipid particle; embryonic tagma; wing vein; embryonic head; cell part; acellular anatomical structure; intracellular organelle; crossvein; secondary pigment cell; intracellular. The phenotypic classes of alleles include: lethal; phenotype; increased mortality during development; lethal - all die before end of prepupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0261989	CG42807	-0.346564137	0.311424181	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG42807 (FBgn0261989). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:13570595..13572759. It has the cytological map location 50B2. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. The phenotypic class of allele includes: viable.
FBgn0031488	CG17265	-0.346189062	0.393181173	0.999936032	CCDC85C	CCDC85C;CCDC85B;CCDC85A	high;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17265 (FBgn0031488). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:2999286..3016069. It has the cytological map location 23C4. Protein features are: CCDC85 family. Its molecular function is unknown. It is involved in the biological process described with: RNA interference. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during late pupal stages.  "
FBgn0029095	aru	-0.346077608	0.410058651	0.999936032	NA	EPS8L2;EPS8;EPS8L1;EPS8L3	high;moderate;moderate;moderate	NA	NA	NA	"The gene arouser is referred to in FlyBase by the symbol Dmel\aru (CG4276, FBgn0029095). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:861849..868354. It has the cytological map location 21E2. Protein features are: Epidermal growth factor receptor kinase substrate, phosphotyrosine-binding domain; Eps8, SH3 domain; PH domain-like; SH3 domain; Tensin/EPS8 phosphotyrosine-binding domain. Its molecular function is unknown. It is involved in the biological process described with: regulation of synapse structure or activity; olfactory behavior; memory; response to ethanol. 11 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; bouton. The phenotypic classes of alleles include: visible; increased mortality during development; phenotype; memory defective; chemical resistant. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 06-18 hour embryonic stages.  "
FBgn0036833	CG3819	-0.345756199	0.286877067	0.999936032	NA	ENDOG	moderate	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG3819 (FBgn0036833). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:18920430..18922108. It has the cytological map location 75E6. Protein features are: DNA/RNA non-specific endonuclease. Its molecular function is described by: metal ion binding; nucleic acid binding; hydrolase activity. It is involved in the biological process described with: apoptotic DNA fragmentation. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: planar polarity defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period.
FBgn0000579	Eno	-0.345683619	0.305886379	0.999936032	NA	ENO1;ENO3;ENO2	high;moderate;moderate	NA	NA	NA	"The gene Enolase is referred to in FlyBase by the symbol Dmel\Eno (CG17654, FBgn0000579). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (2 unique). Gene sequence location is 2L:1724768..1729636. It has the cytological map location 22B1. Protein features are: Enolase; Enolase C-terminal domain-like; Enolase N-terminal domain-like; Enolase, C-terminal TIM barrel domain; Enolase, N-terminal; Enolase, conserved site; Enolase-like superfamily. Its molecular function is described by: phosphopyruvate hydratase activity; magnesium ion binding. It is involved in the biological process described with: glycolytic process; regulation of glucose metabolic process. 21 alleles are reported. The phenotype of these alleles manifest in: pupa. The phenotypic classes of alleles include: phenotype; increased mortality during development; viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0037384	dgrn	-0.34556535	0.388055883	0.999936032	NA	RNF4	high	NA	NA	NA	"The gene degringolade is referred to in FlyBase by the symbol Dmel\dgrn (CG10981, FBgn0037384). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3R:5824615..5826576. It has the cytological map location 83C4. Protein features are: Zinc finger, RING-type; Zinc finger, RING-type, conserved site; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: SUMO binding; RNA polymerase II repressing transcription factor binding; zinc ion binding; ubiquitin protein ligase activity. It is involved in the biological process described with: proteasome-mediated ubiquitin-dependent protein catabolic process; neurogenesis; double-strand break repair via homologous recombination; sex determination; positive regulation of transcription, DNA-templated; regulation of establishment of protein localization; protein ubiquitination; regulation of embryonic development; regulation of protein binding. 15 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; female sterile; phenotype; increased mortality during development; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0051267	CG31267	-0.345552952	0.308218094	0.999936032	NA	CFD;KLK14;KLK13	low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31267 (FBgn0051267). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:17134197..17135283. It has the cytological map location 89F1. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: sensory perception of pain; proteolysis. 2 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: pain response defective; viable; flightless. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0051005	qless	-0.345322362	0.374823778	0.999936032	NA	PDSS1	high	NA	NA	NA	"The gene qless is referred to in FlyBase by the symbol Dmel\qless (CG31005, FBgn0051005). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:31236035..31252608. It has the cytological map location 100B8. Protein features are: Isoprenoid synthase domain; Polyprenyl synthetase; Polyprenyl synthetase, conserved site. Its molecular function is unknown. It is involved in the biological process described with: negative regulation of apoptotic process; isoprenoid biosynthetic process; response to mitochondrial depolarisation; neuroblast development. 13 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval neuroblast. The phenotypic classes of alleles include: stress response defective; increased mortality; phenotype; increased cell death. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 12-18 embryonic stages.  "
FBgn0022288	l(2)09851	-0.345264078	0.339950678	0.999936032	NA	GRWD1	high	NA	NA	NA	"The gene lethal (2) 09851 is referred to in FlyBase by the symbol Dmel\l(2)09851 (CG12792, FBgn0022288). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:5754517..5756327. It has the cytological map location 41F9. Protein features are: G-protein beta WD-40 repeat; Histone-binding protein RBBP4, N-terminal; WD40 repeat; WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: . It is involved in the biological process described with: . 8 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: viable; visible; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0000667	Actn	-0.345059253	0.349723028	0.999936032	NA	ACTN2;ACTN1;ACTN4;ACTN3;SPTBN5	high;moderate;moderate;moderate;low	NA	NA	NA	"The gene ‘± actinin is referred to in FlyBase by the symbol Dmel\Actn (CG4376, FBgn0000667). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (4 unique). Gene sequence location is X:2023822..2042311. It has the cytological map location 2C4-2C7. Protein features are: Actinin-type actin-binding domain, conserved site; Calponin homology domain; EF-Hand 1, calcium-binding site; EF-hand domain; EF-hand domain pair; EF-hand, Ca insensitive; Spectrin repeat; Spectrin/alpha-actinin. Its molecular function is described by: protein binding; actin filament binding; actin binding; calcium ion binding. It is involved in the biological process described with: actin cytoskeleton reorganization; flight behavior; sarcomere organization; actin filament bundle assembly; cytoskeletal anchoring at plasma membrane. 44 alleles are reported. The phenotypes of these alleles manifest in: external sensory organ; adult tagma; egg; adult thoracic segment; ovary; cell cluster organ; reproductive system; thorax; trichogen cell; head; gonad. The phenotypic classes of alleles include: increased mortality during development; viable; phenotype; fertile; some die during pupal stage; lethal - all die before end of pupal stage; lethal - all die before end of P-stage; small body. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0266702	CR45192	-0.344950785	0.2866516	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45192 (FBgn0266702). It is a non_protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts. Gene sequence location is 3R:5835478..5836178. It has the cytological map location 83C4-83C5. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0035906	GstO2	-0.344816918	0.319348697	0.999936032	NA	GSTO1;GSTO2	moderate;moderate	NA	NA	NA	"The gene Glutathione S transferase O2 is referred to in FlyBase by the symbol Dmel\GstO2 (CG6673, FBgn0035906). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:8521429..8523501. It has the cytological map location 66D5. Protein features are: Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Glutathione S-transferase, omega-class; Thioredoxin-like fold. Its molecular function is described by: transferase activity, transferring sulfur-containing groups; glutathione dehydrogenase (ascorbate) activity; glutathione binding; protein homodimerization activity; glutathione transferase activity. It is involved in the biological process described with: negative regulation of innate immune response; toxin catabolic process; glutathione metabolic process; defense response to Gram-negative bacterium. 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: short lived; fertile; viable; chemical sensitive; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, during early larval stages.  "
FBgn0039075	CG4393	-0.344804111	0.400827563	0.999936032	NA	ANKS1B;ANKS1A	high;high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG4393 (FBgn0039075). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:23375928..23384777. It has the cytological map location 94F1. Protein features are: Ankyrin repeat; Ankyrin repeat and SAM domain-containing protein 1; Ankyrin repeat-containing domain; PH domain-like; PTB/PI domain; Sterile alpha motif domain; Sterile alpha motif/pointed domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: viable; visible; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-18 embryonic stages.
FBgn0029161	slmo	-0.344767611	0.311437035	0.999936032	NA	PRELID3B;PRELID3A	high;moderate	NA	NA	NA	"The gene slowmo is referred to in FlyBase by the symbol Dmel\slmo (CG9131, FBgn0029161). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is 2L:6046516..6048706. It has the cytological map location 26B3. Protein features are: PRELI/MSF1 domain. Its molecular function is described by: phosphatidic acid transporter activity. It is involved in the biological process described with: peristalsis; germarium-derived oocyte differentiation; larval locomotory behavior; spermatogenesis. 7 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; wing; mesothoracic tergum. The phenotypic classes of alleles include: lethal; increased mortality; visible; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed during early larval stages, during late pupal stages, in stages of adults of both sexes.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0025592	Gk1	-0.344751848	0.316173731	0.999936032	NA	GK;GK2;GK3P;SHPK;GK5	high;moderate;moderate;moderate;low	NA	NA	NA	"The gene Glycerol kinase 1 is referred to in FlyBase by the symbol Dmel\Gk1 (CG18374, FBgn0025592). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:202098..205844. It has the cytological map location 61B2. Protein features are: Carbohydrate kinase, FGGY; Carbohydrate kinase, FGGY, C-terminal; Carbohydrate kinase, FGGY, N-terminal; Carbohydrate kinase, FGGY, conserved site; Glycerol kinase. Its molecular function is described by: glycerol kinase activity. It is involved in the biological process described with: glycerol metabolic process; triglyceride metabolic process; glycerol-3-phosphate biosynthetic process. 10 alleles are reported. The phenotypes of these alleles manifest in: wing; melanotic mass. The phenotypic classes of alleles include: fertile; visible; viable; melanotic mass phenotype; chemical sensitive; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0053143	CG33143	-0.344698067	0.409002709	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG33143 (FBgn0053143). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 2R:22614328..22634084. It has the cytological map location 58F2. Protein features are: Fibronectin type III; Fibronectin type III domain-containing protein 5, C-terminal domain; Immunoglobulin-like fold. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-18 embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0040091	Ugt58Fa	-0.344669835	0.376146606	0.999936032	NA	UGT1A3;UGT2B10;UGT1A1;UGT3A1;UGT8;UGT2B4;UGT2B15;UGT2B28;UGT2A2;UGT3A2;UGT2B17;UGT2B11;UGT2A3;UGT2B7	moderate;moderate;low;low;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene Ugt58Fa is referred to in FlyBase by the symbol Dmel\Ugt58Fa (CG4414, FBgn0040091). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:22641786..22643917. It has the cytological map location 58F3. Protein features are: UDP-glucuronosyl/UDP-glucosyltransferase. Its molecular function is described by: glucuronosyltransferase activity. It is involved in the biological process described with: metabolic process. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 06-24 hour embryonic stages, during early larval stages.  "
FBgn0041789	Pax	-0.344648158	0.322059639	0.999936032	NA	TGFB1I1;PXN;LPXN	high;moderate;moderate	NA	NA	NA	"The gene Paxillin is referred to in FlyBase by the symbol Dmel\Pax (CG31794, FBgn0041789). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (6 unique). Gene sequence location is 2L:19400753..19426596. It has the cytological map location 37D5-37D7. Protein features are: Paxillin; Zinc finger, LIM-type. Its molecular function is unknown. It is involved in the biological process described with: leg disc development; regulation of myoblast fusion; cell-matrix adhesion; wing disc development; dorsal appendage formation; regulation of autophagy; cytoskeletal anchoring at plasma membrane; regulation of GTPase activity. 40 alleles are reported. The phenotypes of these alleles manifest in: multi-tissue structure; intracellular organelle; germline cyst; adipose system; dorsal acute muscle 1; presumptive embryonic/larval system; intracellular; embryonic/larval epidermis; ventral acute muscle; cuboidal/columnar epithelium; ovariole; organelle; developing embryonic structure. The phenotypic classes of alleles include: partially lethal - majority live; lethal - all die before end of pupal stage; fertile; lethal; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages.  "
FBgn0010263	Rbp9	-0.344397321	0.404952983	0.999936032	NA	ELAVL4;ELAVL3;ELAVL2;ELAVL1	moderate;moderate;moderate;moderate	NA	NA	NA	"The gene RNA-binding protein 9 is referred to in FlyBase by the symbol Dmel\Rbp9 (CG3151, FBgn0010263). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (3 unique). Gene sequence location is 2L:2954762..2968434. It has the cytological map location 23C3. Protein features are: Paraneoplastic encephalomyelitis antigen; RNA recognition motif domain; Splicing factor ELAV/Hu; Splicing factor ELAV/Hu, RNA recognition motif 1. Its molecular function is described by: RNA binding; mRNA binding. It is involved in the biological process described with: oogenesis; germarium-derived egg chamber formation; germ cell proliferation; establishment of blood-brain barrier. 40 alleles are reported. The phenotypes of these alleles manifest in: NMJ bouton; fusome; cystocyte; nurse cell; embryonic/larval neuromuscular junction; germarium; mesothoracic tergum; ovariole; egg chamber. The phenotypic classes of alleles include: wild-type; locomotor behavior defective; increased mortality during development; phenotype; visible; increased mortality; female sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages, in stages of adults of both sexes.  "
FBgn0025621	CG16989	-0.344353377	0.325540452	0.999936032	HEATR6	HEATR6	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG16989 (FBgn0025621). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:793147..797061. It has the cytological map location 1C5. Protein features are: Armadillo-like helical; Armadillo-type fold; Domain of unknown function DUF4042. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0020300	geko	-0.344256312	0.412461528	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene geko is referred to in FlyBase by the symbol Dmel\geko (CG13695, FBgn0020300). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:18139402..18145418. It has the cytological map location 75B11-75B12. Its molecular function is described by: . It is involved in the biological process described with: behavioral response to ethanol; sensory perception of smell. 11 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: smell perception defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0031188	CG14613	-0.344194843	0.337975362	0.999936032	NA	FAM210A	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14613 (FBgn0031188). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:22469981..22472021. It has the cytological map location 20C1. Protein features are: Domain of unknown function DUF1279. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0053100	eIF4EHP	-0.34407999	0.339974365	0.999936032	NA	EIF4E2	high	NA	NA	NA	"The gene eukaryotic translation initiation factor 4E homologous protein is referred to in FlyBase by the symbol Dmel\eIF4EHP (CG33100, FBgn0053100). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 3R:24063077..24108960. It has the cytological map location 95D11-95E1. Protein features are: Translation Initiation factor eIF- 4e; Translation Initiation factor eIF- 4e-like. Its molecular function is described by: translation initiation factor activity; RNA 7-methylguanosine cap binding; translation repressor activity; protein binding. It is involved in the biological process described with: positive regulation of ecdysteroid biosynthetic process; negative regulation of translation; inter-male aggressive behavior; translational initiation. 38 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; mesothoracic tergum; trichogen cell; embryonic head segment; prothoracic gland. The phenotypic classes of alleles include: increased mortality during development; viable; phenotype; visible; size defective; decreased cell size; body size defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0000640	Fbp2	-0.344027426	0.222296919	0.999936032	NA	HPGD	moderate	NA	NA	NA	"The gene Fat body protein 2 is referred to in FlyBase by the symbol Dmel\Fbp2 (CG3763, FBgn0000640). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:9426784..9427917. It has the cytological map location 30B3. Protein features are: Alcohol dehydrogenase, Ceratitis-type; Alcohol dehydrogenase, insect-type; NAD(P)-binding domain; Short-chain dehydrogenase/reductase SDR. Its molecular function is described by: nutrient reservoir activity; alcohol dehydrogenase (NAD) activity. It is involved in the biological process described with: oxidation-reduction process. 5 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: lethal - all die during P-stage; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of no expression detected.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0015756	RpL9	-0.343692236	0.307563498	0.999936032	NA	RPL9	high	NA	NA	NA	"The gene Ribosomal protein L9 is referred to in FlyBase by the symbol Dmel\RpL9 (CG6141, FBgn0015756). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:11002758..11004189. It has the cytological map location 32C1. Protein features are: Ribosomal protein L6; Ribosomal protein L6, alpha-beta domain; Ribosomal protein L6, conserved site-2. Its molecular function is described by: rRNA binding; structural constituent of ribosome; RNA binding. It is involved in the biological process described with: translation; cytoplasmic translation. 10 alleles are reported. The phenotypes of these alleles manifest in: macrochaeta; eye. The phenotypic classes of alleles include: lethal - all die before end of P-stage; lethal; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages.  "
FBgn0000283	Cp190	-0.343671886	0.360064395	0.999936032	NA	E4F1;ZBTB37;RP1;LEO1;DMP1;IBSP	low;low;low;low;low;low	DNA-binding with transcription factor activity	NA	NA	"The gene Centrosomal protein 190kD is referred to in FlyBase by the symbol Dmel\Cp190 (CG6384, FBgn0000283). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:15270432..15275241. It has the cytological map location 88E9-88E11. Protein features are: BTB/POZ domain; SKP1/BTB/POZ domain; Zinc finger C2H2-type. Its molecular function is described by: protein homodimerization activity; POZ domain binding; DNA binding; microtubule binding; chromatin insulator sequence binding; chromatin binding; protein binding. It is involved in the biological process described with: regulation of gene expression; positive regulation of chromatin silencing; regulation of cytoskeleton organization; regulation of transcription from RNA polymerase II promoter; nuclear axial expansion; gene looping; microtubule-based process. 34 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval salivary gland; centrosome; microtubule; pretarsus; eye; tarsal segment; cleavage nucleus. The phenotypic classes of alleles include: some die during third instar larval stage; viable; increased mortality during development; phenotype; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0039627	CG11837	-0.343670443	0.35547781	0.999936032	DIMT1	DIMT1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11837 (FBgn0039627). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:29049493..29050721. It has the cytological map location 98F6. Protein features are: Ribosomal RNA adenine dimethylase; Ribosomal RNA adenine methylase transferase, N-terminal; Ribosomal RNA adenine methylase transferase, conserved site; Ribosomal RNA adenine methyltransferase KsgA/Erm; S-adenosyl-L-methionine-dependent methyltransferase. Its molecular function is described by: rRNA (adenine-N6,N6-)-dimethyltransferase activity. It is involved in the biological process described with: sleep; rRNA modification. 4 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; ganglion mother cell. The phenotypic classes of alleles include: lethal; visible; viable; neuroanatomy defective; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0085346	CG34317	-0.343576325	0.350066173	0.999936032	NA	RPP14	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG34317 (FBgn0085346). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:30056859..30058131. It has the cytological map location 99D3. Protein features are: Ribonuclease P/MRP protein subunit. Its molecular function is described by: ribonuclease P activity. It is involved in the biological process described with: tRNA 5'-leader removal. 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 06-12 hour embryonic stages, during early larval stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0260223	CG42497	-0.342599813	0.323505323	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG42497 (FBgn0260223). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:21690215..21691139. It has the cytological map location 57F8. Protein features are: Protein of unknown function DUF4748. Its molecular function is described by: . It is involved in the biological process described with: regulation of dopamine metabolic process. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in stages of adults of both sexes.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0011638	La	-0.342460326	0.323459066	0.999936032	NA	SSB;LARP7	high;low	DNA-binding with transcription factor activity	NA	NA	"The gene La autoantigen-like is referred to in FlyBase by the symbol Dmel\La (CG10922, FBgn0011638). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:20348393..20350012. It has the cytological map location 38C5. Protein features are: La protein, RNA-binding domain; La-type HTH domain; Lupus La protein; RNA recognition motif domain; Winged helix-turn-helix DNA-binding domain. Its molecular function is described by: mRNA binding; 5S rRNA primary transcript binding. It is involved in the biological process described with: RNA processing. 6 alleles are reported. The phenotypes of these alleles manifest in: midgut constriction 1; midgut constriction; midgut constriction 2; trichogen cell; embryonic/larval midgut; midgut constriction 3. The phenotypic classes of alleles include: visible; viable; lethal; flightless; short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 06-12 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0030616	RpL37a	-0.342363198	0.308641223	0.999936032	RPL37	RPL37	high	NA	NA	NA	"The gene Ribosomal protein L37a is referred to in FlyBase by the symbol Dmel\RpL37a (CG9091, FBgn0030616). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:15137870..15139367. It has the cytological map location 13B1. Protein features are: Ribosomal protein L37ae/L37e; Ribosomal protein L37e; Ribosomal protein L37e, conserved site; Zinc-binding ribosomal protein. Its molecular function is described by: RNA binding; structural constituent of ribosome. It is involved in the biological process described with: translation; cytoplasmic translation. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, during early larval stages.  "
FBgn0003731	Egfr	-0.342339016	0.372052873	0.999936032	NA	ERBB4;EGFR;ERBB2;ERBB3	high;high;moderate;moderate	NA	transmembrane protein	NA	"The gene Epidermal growth factor receptor is referred to in FlyBase by the symbol Dmel\Egfr (CG10079, FBgn0003731). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:21522420..21559977. It has the cytological map location 57E9-57F1. Protein features are: 14-3-3 domain; 14-3-3 protein; 14-3-3 protein, conserved site; Furin-like cysteine-rich domain; Furin-like repeat; Growth factor receptor cysteine-rich domain; Growth factor receptor domain 4; Leucine-rich repeat domain, L domain-like; Protein kinase domain; Protein kinase, ATP binding site; Protein kinase-like domain; Receptor L-domain; Serine-threonine/tyrosine-protein kinase, catalytic domain; Tyrosine protein kinase, EGF/ERB/XmrK receptor; Tyrosine-protein kinase, active site; Tyrosine-protein kinase, catalytic domain. Its molecular function is described by: ATP binding; protein binding; epidermal growth factor-activated receptor activity; protein domain specific binding; transmembrane receptor protein tyrosine kinase activity; protein tyrosine kinase activity; signal transducer, downstream of receptor, with protein tyrosine kinase activity; transmembrane signaling receptor activity. It is involved in the biological process described with 93 unique terms, many of which group under: system process; learning; negative regulation of gene expression; biological adhesion; organelle organization; regulation of cell proliferation; ameboidal-type cell migration; regulation of hemocyte differentiation; positive regulation of wound healing; determination of adult lifespan; periodic partitioning; male gamete generation; maintenance of epithelial integrity, open tracheal system; maintenance of cell number; progression of morphogenetic furrow involved in compound eye morphogenesis; cell-cell adhesion; establishment or maintenance of bipolar cell polarity. 167 alleles are reported. The phenotypes of these alleles manifest in: glial cell; embryonic imaginal precursor; embryonic/larval neuron; tracheal branch primordium; spiracular histoblast nest abdominal 4; stage 8 embryo; embryonic/first instar larval cuticle; neuroblast NB3-2; synaptic neuropil subdomain; cephalopharyngeal skeleton; genital disc primordium; ventral histoblast nest abdominal 3; ocellar bristle; cellular process; midgut constriction 3; abdominal larval oenocyte group; dorsal oblique muscle; ventral multidendritic neuron; posterior dorsal histoblast nest abdominal 2; adult tracheal system; external encapsulating structure; tracheal lumen; lamina monopolar neuron L3. The phenotypic classes of alleles include: cell number defective; visible; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, during early pupal stages.  "
FBgn0033529	CG17765	-0.341736518	0.333721795	0.999936032	PEF1	PEF1;CAPNS1;GCA;SRI;PDCD6	high;moderate;moderate;moderate;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17765 (FBgn0033529). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:10480163..10481886. It has the cytological map location 47A11. Protein features are: EF-Hand 1, calcium-binding site; EF-hand domain; EF-hand domain pair. Its molecular function is described by: calcium ion binding. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0086358	Tab2	-0.341698305	0.363597099	0.999936032	NA	TAB3;TAB2	high;high	DNA-binding with transcription factor activity	NA	NA	"The gene TAK1-associated binding protein 2 is referred to in FlyBase by the symbol Dmel\Tab2 (CG7417, FBgn0086358). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2R:19292529..19304508. It has the cytological map location 56C8-56C9. Protein features are: Leucine-rich repeat domain, L domain-like; Ubiquitin system component Cue; Zinc finger, RanBP2-type. Its molecular function is unknown. It is involved in the biological process described with: positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria; dendrite morphogenesis; peptidoglycan recognition protein signaling pathway; lateral inhibition; male courtship behavior, veined wing generated song production; positive regulation of protein import into nucleus, translocation; positive regulation of defense response to virus by host. 51 alleles are reported. The phenotypes of these alleles manifest in: adult external thorax; trichogen cell; chaeta; mesothoracic tergum; adult thoracic sensillum; scutellum. The phenotypic classes of alleles include: visible; viable; song defective; body color defective; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0265356	tn	-0.341695818	0.408227438	0.999936032	NA	TRIM2;TRIM3	high;low	Maybe TF	NA	NA	"The gene thin is referred to in FlyBase by the symbol Dmel\tn (CG15105, FBgn0265356). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (5 unique). Gene sequence location is 2R:18987344..19008944. It has the cytological map location 55F-56B. Protein features are: NHL repeat; NHL repeat, subgroup; Six-bladed beta-propeller, TolB-like; Zinc finger, C3HC4 RING-type; Zinc finger, RING-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: zinc ion binding; metal ion binding; ubiquitin-protein transferase activity. It is involved in the biological process described with: muscle cell cellular homeostasis; muscle fiber development; larval locomotory behavior; protein ubiquitination; myofibril assembly; striated muscle contraction. 20 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval somatic muscle; visceral muscle fiber; myofibril; sarcomere; filamentous actin. The phenotypic classes of alleles include: fertile; increased mortality; some die during P-stage; flight defective; phenotype; viable; increased mortality during development; visible; size defective."
FBgn0031549	Spindly	-0.341672374	0.340305363	0.999936032	NA	SPDL1	high	NA	NA	NA	"The gene Spindly is referred to in FlyBase by the symbol Dmel\Spindly (CG15415, FBgn0031549). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:3527387..3530317. It has the cytological map location 24A1. Its molecular function is described by: protein phosphatase 1 binding. It is involved in the biological process described with: regulation of mitotic metaphase/anaphase transition. 6 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0036648	CG4098	-0.341653828	0.412434795	0.999936032	NUDT9	NUDT9	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4098 (FBgn0036648). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:16608138..16609347. It has the cytological map location 73B1. Protein features are: NUDIX hydrolase domain; NUDIX hydrolase domain-like. Its molecular function is described by: adenosine-diphosphatase activity. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0003502	Btk29A	-0.341610291	0.414773732	0.999936032	NA	TEC;ITK;TXK;BMX;BTK;LCK;FRK;HCK;LYN;SRC;BLK;ABL1;ABL2;FYN;FGR;SRMS	high;moderate;moderate;moderate;moderate;low;low;low;low;low;low;low;low;low;low;moderate	NA	NA	NA	"The gene Btk family kinase at 29A is referred to in FlyBase by the symbol Dmel\Btk29A (CG8049, FBgn0003502). It is a protein_coding_gene from Drosophila melanogaster. It has 8 annotated transcripts and 8 polypeptides (4 unique). Gene sequence location is 2L:8258373..8301079. It has the cytological map location 29A1-29A3. Protein features are: PH domain-like; Pleckstrin homology domain; Protein kinase domain; Protein kinase, ATP binding site; Protein kinase-like domain; SH2 domain; SH3 domain; Serine-threonine/tyrosine-protein kinase, catalytic domain; Tyrosine-protein kinase, active site; Tyrosine-protein kinase, catalytic domain; Zinc finger, Btk motif. Its molecular function is described by: protein tyrosine kinase activity; ATP binding; non-membrane spanning protein tyrosine kinase activity. It is involved in the biological process described with 27 unique terms, many of which group under: behavior; peptidyl-tyrosine phosphorylation; actin filament-based process; defense response; cell proliferation; imaginal disc-derived appendage development; chromosome organization; spiracle morphogenesis, open tracheal system; actin cytoskeleton organization; regulation of cell proliferation; cell surface receptor signaling pathway; instar larval or pupal development; neurological system process; mating behavior. 64 alleles are reported. The phenotypes of these alleles manifest in: foregut; embryonic/larval cuticle; muscle attachment site; dorsal closure embryo; adult abdomen; spectrosome; karyosome; epithelial cell; egg; ring canal; apodeme. The phenotypic classes of alleles include: lethal; increased mortality during development; phenotype; lethal - all die before end of pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages.  "
FBgn0040832	CG8012	-0.341290497	0.319284806	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG8012 (FBgn0040832). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:8215280..8216198. It has the cytological map location 66C1. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed during late pupal stages.
FBgn0015036	Cyp4ae1	-0.341005157	0.316066718	0.999936032	NA	CYP4V2;CYP4A11;CYP4Z1;CYP4B1;CYP4F11;CYP4X1;CYP4F12;CYP4A22;CYP4F8;CYP26B1;CYP4F3;CYP4F2;CYP4F22	moderate;low;low;low;moderate;low;low;low;moderate;moderate;low;low;moderate	NA	NA	NA	"The gene Cytochrome P450-4ae1 is referred to in FlyBase by the symbol Dmel\Cyp4ae1 (CG10755, FBgn0015036). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:2179007..2180998. It has the cytological map location 2E1. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Its molecular function is described by: iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; heme binding. It is involved in the biological process described with: oxidation-reduction process. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0031245	CG3625	-0.34092845	0.310708768	0.999936032	NA	AIG1;ADTRP	high;moderate	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG3625 (FBgn0031245). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 2L:283385..291795. It has the cytological map location 21B7. Protein features are: FAR-17a/AIG1-like protein. Its molecular function is unknown. The biological processes in which it is involved are not known. 13 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; lethal - all die during P-stage; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 06-12 hour embryonic stages.
FBgn0265187	CG44252	-0.340924414	0.412689989	0.999936032	NA	SLC27A4;SLC27A1;SLC27A6;SLC27A2;SLC27A5;SLC27A3	high;moderate;moderate;moderate;moderate;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG44252 (FBgn0265187). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2R:23055474..23061549. It has the cytological map location 59C2. Protein features are: AMP-binding, conserved site; AMP-dependent synthetase/ligase. Its molecular function is described by: very long-chain fatty acid-CoA ligase activity; fatty acid transporter activity. It is involved in the biological process described with: metabolic process; fatty acid transport. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile."
FBgn0037810	sle	-0.340904087	0.388539075	0.999936032	NA	MDN1;SAMD15	low;low	NA	NA	NA	"The gene slender lobes is referred to in FlyBase by the symbol Dmel\sle (CG12819, FBgn0037810). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:10333115..10338265. It has the cytological map location 86A8-86B1. Its molecular function is described by: . It is involved in the biological process described with: rRNA processing; nucleolus organization; ribosomal large subunit assembly. 11 alleles are reported. The phenotypes of these alleles manifest in: somatic precursor cell; somatic stem cell; intracellular organelle part; organelle lumen; membrane-bounded organelle; stem cell; supramolecular polymer; myofibril; neuroblast; intracellular membrane-bounded organelle. The phenotypic classes of alleles include: viable; lethal - all die during larval stage; developmental rate defective; neuroanatomy defective; sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0263029	CG43324	-0.340896201	0.367435117	0.999936032	NA	GNG11;GNGT1;GNG12;GNG3;GNG10;GNG7;GNG4;GNG13;GNG8;GNG5;GNGT2	moderate;high;low;low;low;low;low;low;low;low;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG43324 (FBgn0263029). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:17563606..17564351. It has the cytological map location 54C8. Protein features are: G-protein gamma-like domain; G-protein, gamma subunit. Its molecular function is described by: signal transducer activity. It is involved in the biological process described with: G-protein coupled receptor signaling pathway. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: lethal."
FBgn0005626	ple	-0.340446525	0.339295226	0.999936032	NA	TH;TPH2;PAH;TPH1	high;low;low;low	NA	NA	NA	"The gene pale is referred to in FlyBase by the symbol Dmel\ple (CG10118, FBgn0005626). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:6713356..6719525. It has the cytological map location 65C3. Protein features are: Aromatic amino acid hydroxylase; Aromatic amino acid hydroxylase, C-terminal; Aromatic amino acid hydroxylase, iron/copper binding site; Tyrosine 3-monooxygenase; Tyrosine 3-monooxygenase-like. Its molecular function is described by: iron ion binding; tyrosine 3-monooxygenase activity. It is involved in the biological process described with 17 unique terms, many of which group under: response to stimulus; response to temperature stimulus; response to abiotic stimulus; response to stress; tube development; ameboidal-type cell migration; organonitrogen compound biosynthetic process; response to external stimulus; single-organism behavior; cellular biosynthetic process; response to wounding; oxidation-reduction process; cell migration; taxis; tissue development. 36 alleles are reported. The phenotypes of these alleles manifest in: acellular anatomical structure; embryonic/larval digestive system; embryonic head; embryonic tagma; abdomen; dorsal mesothorax; epithelial tube; neuron; adult sense organ; larva. The phenotypic classes of alleles include: phenotype; visible; increased mortality; behavior defective; locomotor behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the pupal period.  "
FBgn0037796	CG12814	-0.340154928	0.375033332	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12814 (FBgn0037796). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 3R:10171156..10189603. It has the cytological map location 85F16. Protein features are: Zona pellucida domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during late pupal stages.  "
FBgn0039505	CG5934	-0.339767042	0.397503954	0.999936032	NA	SCOC	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG5934 (FBgn0039505). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:27273705..27274565. It has the cytological map location 97F1. Protein features are: Short coiled-coil protein. Its molecular function is unknown. It is involved in the biological process described with: sensory perception of pain. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.
FBgn0265298	SC35	-0.339616851	0.318938527	0.999936032	NA	SRSF2;SRSF8;SRSF10	high;moderate;moderate	Chromatin regulation	NA	NA	"The gene SR family splicing factor SC35 is referred to in FlyBase by the symbol Dmel\SC35 (CG5442, FBgn0265298). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 2L:12431075..12434665. It has the cytological map location 33E4. Protein features are: RNA recognition motif domain. Its molecular function is described by: mRNA binding; protein binding. It is involved in the biological process described with: regulation of mRNA 3'-end processing; regulation of gene expression; regulation of transcriptional start site selection at RNA polymerase II promoter; regulation of alternative mRNA splicing, via spliceosome. 6 alleles are reported. The phenotypes of these alleles manifest in: eye; ommatidium. The phenotypic classes of alleles include: fertile; viable; eye color defective."
FBgn0038269	Rrp6	-0.338857016	0.364639656	0.999936032	NA	EXOSC10	high	NA	NA	NA	"The gene Rrp6 is referred to in FlyBase by the symbol Dmel\Rrp6 (CG7292, FBgn0038269). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:14882498..14886246. It has the cytological map location 88D6. Protein features are: 3'-5' exonuclease domain; Exosome-associated factor Rrp6, N-terminal; HRDC domain; HRDC-like; Ribonuclease H-like domain. Its molecular function is described by: nucleotide binding; 3'-5' exonuclease activity; nucleic acid binding. It is involved in the biological process described with: chromosome segregation; mitotic cell cycle; regulation of gene expression; defense response to virus; mRNA polyadenylation; nuclear RNA surveillance. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal - all die during larval stage; lethal; some die during pupal stage; lethal - all die before end of pupal stage; immune response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0037552	CG7800	-0.338799878	0.414641133	0.999936032	NA	TLR3	low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7800 (FBgn0037552). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:8217957..8219734. It has the cytological map location 84F4. Protein features are: Leucine-rich repeat; Leucine-rich repeat domain, L domain-like; Leucine-rich repeat, typical subtype. Its molecular function is unknown. It is involved in the biological process described with: sensory perception of pain. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: pain response defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0032521	CG7110	-0.338634766	0.349846083	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG7110 (FBgn0032521). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:13398991..13411047. It has the cytological map location 34B10-34B11. Its molecular function is unknown. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-12 hour embryonic stages.
FBgn0035674	CG13295	-0.338624908	0.372216279	0.999936032	TCAIM	TCAIM	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13295 (FBgn0035674). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:6073490..6075245. It has the cytological map location 65A5. Protein features are: Domain of unknown function DUF4460; Domain of unknown function DUF4461; T-cell activation inhibitor, mitochondrial. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0031910	CG15818	-0.338547872	0.286007835	0.999936032	NA	SFTPD	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15818 (FBgn0031910). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:7410909..7412229. It has the cytological map location 27F3. Protein features are: C-type lectin fold; C-type lectin-like; C-type lectin-like/link domain. Its molecular function is described by: carbohydrate binding. The biological processes in which it is involved are not known. 2 alleles are reported. The phenotypes of these alleles manifest in: tormogen cell; trichogen cell. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0033785	Sans	-0.338169668	0.414712279	0.999936032	USH1G	USH1G;ANKS4B	high;moderate	NA	NA	NA	"The gene Scaffold protein containing ankyrin repeats and SAM domain is referred to in FlyBase by the symbol Dmel\Sans (CG13320, FBgn0033785). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:12936891..12940412. It has the cytological map location 49E1. Protein features are: Ankyrin repeat; Ankyrin repeat-containing domain; Sterile alpha motif domain; Sterile alpha motif/pointed domain. Its molecular function is described by: . It is involved in the biological process described with: . 12 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during pupal stage; male fertile; partially lethal - majority die; female fertile; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 06-18 hour embryonic stages, at stages throughout the pupal period.  "
FBgn0030976	CG7378	-0.338093299	0.361182049	0.999936032	NA	DUSP13;DUSP3;DUPD1;DUSP26;DUSP27;SSH3;SSH2;DUSP2;SSH1;DUSP8;STYX;DUSP4;DUSP5;DUSP16;DUSP19;DUSP1	high;moderate;moderate;moderate;moderate;low;low;moderate;low;low;low;low;moderate;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7378 (FBgn0030976). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is X:18900410..18911843. It has the cytological map location 17F2-17F3. Protein features are: Atypical dual specificity phosphatase; Atypical dual specificity phosphatase, subfamily A; Dual specificity phosphatase; Dual specificity phosphatase, catalytic domain; Dual specificity protein phosphatase domain; Protein-tyrosine phosphatase, active site; Protein-tyrosine phosphatase-like; Tyrosine specific protein phosphatases domain. Its molecular function is described by: protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity. It is involved in the biological process described with: protein dephosphorylation. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0036213	RpL10Ab	-0.337793141	0.314861057	0.999936032	NA	RPL10A	high	NA	NA	NA	"The gene Ribosomal protein L10Ab is referred to in FlyBase by the symbol Dmel\RpL10Ab (CG7283, FBgn0036213). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:11822851..11824211. It has the cytological map location 68E1. Protein features are: Ribosomal protein L1; Ribosomal protein L1, 3-layer alpha/beta-sandwich; Ribosomal protein L1-like; Ribosomal protein L1/ribosomal biogenesis protein. Its molecular function is described by: structural constituent of ribosome; RNA binding. It is involved in the biological process described with: maturation of LSU-rRNA; translation; cytoplasmic translation. 12 alleles are reported. The phenotypes of these alleles manifest in: nucleolus; nucleus; egg chamber; follicle cell. The phenotypic classes of alleles include: lethal; lethal - all die before end of larval stage; lethal - all die during larval stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages.  "
FBgn0037566	mRpL1	-0.337648661	0.344442094	0.999936032	NA	MRPL1	high	NA	NA	NA	"The gene mitochondrial ribosomal protein L1 is referred to in FlyBase by the symbol Dmel\mRpL1 (CG7494, FBgn0037566). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:8301440..8302770. It has the cytological map location 84F9-84F10. Protein features are: Ribosomal protein L1, 3-layer alpha/beta-sandwich; Ribosomal protein L1, mitochondrial; Ribosomal protein L1-like; Ribosomal protein L1/ribosomal biogenesis protein. Its molecular function is described by: box H/ACA snoRNA binding; structural constituent of ribosome. It is involved in the biological process described with: maturation of LSU-rRNA; mitochondrial translation; cleavage involved in rRNA processing; rRNA pseudouridine synthesis; translation; snRNA pseudouridine synthesis. 5 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: lethal - all die during larval stage; fertile; viable; visible; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, during early larval stages.  "
FBgn0024983	CG4293	-0.337619683	0.378868171	0.999936032	ERGIC2	ERGIC2	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4293 (FBgn0024983). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (2 unique). Gene sequence location is X:527941..530291. It has the cytological map location 1B8-1B9. Protein features are: Endoplasmic reticulum vesicle transporter, C-terminal. Its molecular function is described by: . It is involved in the biological process described with: ER to Golgi vesicle-mediated transport. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, in adult female stages.  "
FBgn0030504	CG2691	-0.337457572	0.393792502	0.999936032	RRP12	RRP12	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG2691 (FBgn0030504). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:13619276..13624408. It has the cytological map location 12A8-12A9. Protein features are: Armadillo-like helical; Armadillo-type fold; Uncharacterised domain NUC173. Its molecular function is described by: . It is involved in the biological process described with: neuron projection morphogenesis. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, in adult female stages.  "
FBgn0024244	drm	-0.337416693	0.333295232	0.999936032	NA	OSR2;OSR1	moderate;moderate	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene drumstick is referred to in FlyBase by the symbol Dmel\drm (CG10016, FBgn0024244). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:3539247..3548423. It has the cytological map location 24A1. Protein features are: Zinc finger C2H2-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: protein binding; nucleic acid binding. It is involved in the biological process described with 11 unique terms, many of which group under: embryonic pattern specification; pattern specification process; animal organ development; single-organism developmental process; embryonic foregut morphogenesis; regulation of transcription from RNA polymerase II promoter; imaginal disc-derived leg segmentation; multicellular organism development; transcription from RNA polymerase II promoter; foregut morphogenesis; tissue morphogenesis. 22 alleles are reported. The phenotypes of these alleles manifest in: keyhole structure; sclerite; larval mesothoracic segment; embryonic large intestine; proventriculus primordium; embryonic/larval proventriculus; foregut; embryonic proventriculus; larval thoracic segment; epithelium. The phenotypic classes of alleles include: visible; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during early pupal stages.  "
FBgn0026143	CDC45L	-0.337233764	0.396543762	0.999936032	NA	CDC45	high	NA	NA	NA	"The gene CDC45L is referred to in FlyBase by the symbol Dmel\CDC45L (CG3658, FBgn0026143). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:1028291..1030556. It has the cytological map location 1E1. Protein features are: CDC45 family. Its molecular function is described by: DNA replication origin binding; chromatin binding; 3'-5' DNA helicase activity; single-stranded DNA binding. It is involved in the biological process described with 11 unique terms, many of which group under: cell cycle G2/M phase transition; cell cycle G1/S phase transition; heterocycle biosynthetic process; regulation of cellular macromolecule biosynthetic process; mitotic DNA replication; cellular developmental process; regulation of cell cycle G2/M phase transition; neuron development; regulation of nucleobase-containing compound metabolic process; positive regulation of cell cycle phase transition; DNA conformation change. 9 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; ganglion mother cell; embryonic/larval neuroblast; mesothoracic tergum. The phenotypic classes of alleles include: lethal; increased mortality; some die during second instar larval stage; increased mortality during development; phenotype; some die during larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0032850	Kua	-0.337159392	0.369622733	0.999936032	NA	TMEM189-UBE2V1;TMEM189	high;moderate	NA	transmembrane protein	NA	"The gene Kua is referred to in FlyBase by the symbol Dmel\Kua (CG10723, FBgn0032850). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2L:20097581..20103375. It has the cytological map location 38B6-38C1. Protein features are: B domain of TMEM189, localisation domain. Its molecular function is described by: fatty acid alpha-hydroxylase activity; ubiquitin protein ligase binding; ubiquitin protein ligase activity. It is involved in the biological process described with: . 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult male stages.  "
FBgn0050273	CG30273	-0.336633339	0.390699301	0.999936032	NA	LITAF	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG30273 (FBgn0050273). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:22667155..22668848. It has the cytological map location 58F4-58F6. Protein features are: LPS-induced tumour necrosis factor alpha factor. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult male stages.  "
FBgn0032024	CG14273	-0.33655292	0.404094609	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14273 (FBgn0032024). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:8342695..8344378. It has the cytological map location 29B1. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the larval period, during early pupal stages.  "
FBgn0026431	Grip75	-0.336465423	0.422358235	0.999936032	NA	TUBGCP4	high	NA	NA	NA	"The gene Grip75 is referred to in FlyBase by the symbol Dmel\Grip75 (CG6176, FBgn0026431). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:10483295..10485857. It has the cytological map location 31F1. Protein features are: Gamma-tubulin complex component protein. Its molecular function is described by: microtubule minus-end binding; gamma-tubulin binding; structural constituent of cytoskeleton. It is involved in the biological process described with: mitotic cell cycle; cytoplasmic microtubule organization; interphase microtubule nucleation by interphase microtubule organizing center; bicoid mRNA localization; male meiosis cytokinesis; microtubule nucleation; spindle assembly involved in female meiosis II; mitotic spindle assembly. 11 alleles are reported. The phenotypes of these alleles manifest in: condensed chromosome; Nebenkern; macrochaeta; ovariole; spindle; adult cuticle; embryonic/larval neuroblast; mitotic spindle; egg; spermatid. The phenotypic classes of alleles include: mitotic cell cycle defective; meiotic cell cycle defective; viable; female sterile; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0000092	CG2650	-0.336441931	0.288838708	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG2650 (FBgn0000092). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:2692732..2693886. It has the cytological map location 3B2. Protein features are: Haemolymph juvenile hormone binding. Its molecular function is unknown. It is involved in the biological process described with: multicellular organism reproduction; circadian rhythm. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages.
FBgn0030925	Hayan	-0.336441931	0.288838708	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Hayan is referred to in FlyBase by the symbol Dmel\Hayan (CG6361, FBgn0030925). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:18479983..18483772. It has the cytological map location 17B4-17B5. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Proteinase, regulatory CLIP domain; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: regulation of melanization defense response; proteolysis. 12 alleles are reported. The phenotype of these alleles manifest in: trachea. The phenotypic classes of alleles include: increased mortality; increased mortality during development; phenotype; some die during larval stage; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0040239	bc10	-0.336358983	0.349305504	0.999936032	NA	BLCAP	high	NA	transmembrane protein	NA	"The gene bc10 is referred to in FlyBase by the symbol Dmel\bc10 (CG4867, FBgn0040239). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:5565231..5566765. It has the cytological map location 64D3. Protein features are: Bladder cancer-related BC10. Its molecular function is described by: . It is involved in the biological process described with: . 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0037298	CG2604	-0.336294116	0.323723526	0.999936032	SCCPDH	SCCPDH	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG2604 (FBgn0037298). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:5221632..5223365. It has the cytological map location 82F6. Protein features are: NAD(P)-binding domain; Saccharopine dehydrogenase, NADP binding domain. Its molecular function is described by: oxidoreductase activity. It is involved in the biological process described with: chaeta development; oxidation-reduction process; wing disc development. 2 alleles are reported. The phenotype of these alleles manifest in: wing vein. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in stages of adults of both sexes.  "
FBgn0031662	CG3792	-0.336196047	0.363714227	0.999936032	NA	MPDU1	high	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG3792 (FBgn0031662). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:4977312..4978567. It has the cytological map location 25B5. Protein features are: Mannose-P-dolichol utilization defect 1 protein; PQ-loop repeat. Its molecular function is unknown. It is involved in the biological process described with: dolichol-linked oligosaccharide biosynthetic process; protein glycosylation. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed during early larval stages.
FBgn0030653	CG7860	-0.336170398	0.423459683	0.999936032	NA	ASRGL1;TASP1	high;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7860 (FBgn0030653). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:15568993..15570369. It has the cytological map location 13D3. Protein features are: Asparaginase-like 1, metazoa; Nucleophile aminohydrolases, N-terminal; Peptidase T2, asparaginase 2. Its molecular function is described by: asparaginase activity. It is involved in the biological process described with: salivary gland cell autophagic cell death; autophagic cell death; asparagine catabolic process via L-aspartate. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed at stages throughout the pupal period.  "
FBgn0013272	Gp150	-0.335902556	0.322147939	0.999936032	NA	TLR3	low	NA	transmembrane protein	NA	"The gene Gp150 is referred to in FlyBase by the symbol Dmel\Gp150 (CG5820, FBgn0013272). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (3 unique). Gene sequence location is 2R:22317662..22329416. It has the cytological map location 58D3. Protein features are: Leucine-rich repeat; Leucine-rich repeat domain, L domain-like; Leucine-rich repeat, typical subtype; WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. It is involved in the biological process described with: compound eye development; inter-male aggressive behavior; transmembrane receptor protein tyrosine phosphatase signaling pathway. 33 alleles are reported. The phenotypes of these alleles manifest in: cell part; organelle part; photoreceptor cell R8; acellular anatomical structure; eo support cell; wing vein; contractile fiber; postfrons; supramolecular fiber; inner photoreceptor cell; head capsule; tergum. The phenotypic classes of alleles include: male semi-sterile; increased mortality; viable; phenotype; visible; sterile; some die during larval stage; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0267534	CR45874	-0.335785003	0.422782111	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45874 (FBgn0267534). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3L:9510017..9510889. It has the cytological map location 67B11. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0031912	muc	-0.335750086	0.326481305	0.999936032	NA	DLAT;PDHX	high;moderate	NA	NA	NA	NA
FBgn0265274	Inx3	-0.33568346	0.381995544	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene Innexin 3 is referred to in FlyBase by the symbol Dmel\Inx3 (CG1448, FBgn0265274). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:28853606..28859497. It has the cytological map location 98E6-98F1. Protein features are: Innexin. Its molecular function is described by: gap junction channel activity. It is involved in the biological process described with: dorsal closure; intercellular transport. 9 alleles are reported. The phenotypes of these alleles manifest in: embryonic/first instar larval cuticle; denticle belt. The phenotypic classes of alleles include: cell polarity defective; viable."
FBgn0035878	CG7182	-0.335266862	0.341585052	0.999936032	NA	HSPA14	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG7182 (FBgn0035878). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:8344421..8346382. It has the cytological map location 66C8. Protein features are: Heat shock protein 70 family. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval hemocyte. The phenotypic classes of alleles include: viable; flight defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0029994	CG2254	-0.335134481	0.285685379	0.999936032	NA	HSD17B11;HSD17B13;DHRS3;SDR16C5;RDH10	moderate;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG2254 (FBgn0029994). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:8078350..8081605. It has the cytological map location 7D5. Protein features are: NAD(P)-binding domain; Short-chain dehydrogenase/reductase SDR. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during early larval stages, in adult male stages.  "
FBgn0027572	CG5009	-0.334981727	0.331394926	0.999936032	ACOX1	ACOX1;ACOX2	high;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5009 (FBgn0027572). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:17760940..17764541. It has the cytological map location 54E8. Protein features are: Acyl-CoA dehydrogenase/oxidase C-terminal; Acyl-CoA dehydrogenase/oxidase, N-terminal; Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain; Acyl-CoA oxidase; Acyl-CoA oxidase, C-terminal; Acyl-CoA oxidase/dehydrogenase, central domain; Acyl-coenzyme A oxidase, N-terminal; Peroxisomal acyl-coenzyme A oxidase. Its molecular function is described by: flavin adenine dinucleotide binding; FAD binding; acyl-CoA oxidase activity; acyl-CoA dehydrogenase activity. It is involved in the biological process described with: fatty acid beta-oxidation using acyl-CoA dehydrogenase; generation of precursor metabolites and energy; fatty acid beta-oxidation; prostaglandin metabolic process; fatty acid oxidation; lipid metabolic process. 7 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval hemocyte. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed during early pupal stages.  "
FBgn0259111	Ndae1	-0.334782975	0.350444993	0.999936032	NA	SLC4A7;SLC4A8;SLC4A10;SLC4A1;SLC4A3;SLC4A2;SLC4A5;SLC4A4;SLC4A9;SLC4A11	high;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene Na<sup>+</sup>-driven anion exchanger 1 is referred to in FlyBase by the symbol Dmel\Ndae1 (CG42253, FBgn0259111). It is a protein_coding_gene from Drosophila melanogaster. It has 10 annotated transcripts and 10 polypeptides (all unique). Gene sequence location is 2L:7223328..7249343. It has the cytological map location 27E5-27E6. Protein features are: Anion exchange protein; Band 3 cytoplasmic domain; Bicarbonate transporter, C-terminal; Bicarbonate transporter, eukaryotic; Phosphotransferase/anion transporter; Sodium bicarbonate cotransporter. Its molecular function is described by: anion:anion antiporter activity; sodium:bicarbonate symporter activity; inorganic anion exchanger activity. It is involved in the biological process described with: regulation of cellular pH; proton transport; regulation of intracellular pH; chloride transport; bicarbonate transport; sodium ion transport. 14 alleles are reported. The phenotype of these alleles manifest in: imaginal disc. The phenotypic classes of alleles include: lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0039321	CG10550	-0.334731905	0.347594448	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10550 (FBgn0039321). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:25306407..25308391. It has the cytological map location 96D1. Protein features are: CHK kinase-like; Protein kinase-like domain; Protein of unknown function DUF227. Its molecular function is described by: . The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during late pupal stages, in adult male stages.  "
FBgn0004580	Cbp53E	-0.334648168	0.36087535	0.999936032	SCGN	CALB2;CALB1;SCGN	high;moderate;moderate	NA	NA	NA	"The gene Calbindin 53E is referred to in FlyBase by the symbol Dmel\Cbp53E (CG6702, FBgn0004580). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:16973927..16996057. It has the cytological map location 53E4. Protein features are: EF-Hand 1, calcium-binding site; EF-hand domain; EF-hand domain pair. Its molecular function is described by: calcium ion binding. It is involved in the biological process described with: negative regulation of response to wounding; regulation of cytosolic calcium ion concentration. 12 alleles are reported. The phenotypes of these alleles manifest in: olfactory receptor neuron; type Ib terminal bouton; trichogen cell; type II bouton; type III bouton. The phenotypic classes of alleles include: neuroanatomy defective; increased mortality; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0259984	kuz	-0.334282978	0.421662456	0.999936032	NA	ADAM10	high	NA	transmembrane protein	NA	"The gene kuzbanian is referred to in FlyBase by the symbol Dmel\kuz (CG7147, FBgn0259984). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 2L:13550139..13639411. It has the cytological map location 34C4-34C6. Protein features are: ADAM10/ADAM17 catalytic domain; Disintegrin and metalloproteinase domain-containing protein 10; Disintegrin domain; Metallopeptidase, catalytic domain; Peptidase M12B, ADAM/reprolysin; Peptidase M12B, propeptide. Its molecular function is described by: metalloendopeptidase activity. It is involved in the biological process described with 19 unique terms, many of which group under: endocytosis; muscle structure development; lymph gland development; cellular metabolic process; membrane protein proteolysis; muscle organ development; regulation of cell communication; hematopoietic or lymphoid organ development; regulation of cell morphogenesis involved in differentiation; gliogenesis; establishment of localization. 101 alleles are reported. The phenotypes of these alleles manifest in: embryonic neuroblast; epithelial cell; adult metathoracic segment; neurosecretory neuron; glial cell of the perineurium; muscle cell; EL neuron; adult external mesothorax; border follicle cell; embryonic somatic muscle; neuroblast NB1-1. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; some die during pharate adult stage; cell number defective; phenotype; viable; visible; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0038035	lig3	-0.334162293	0.376497756	0.999936032	LIG3	LIG3	high	NA	NA	NA	"The gene DNA ligase III is referred to in FlyBase by the symbol Dmel\lig3 (CG17227, FBgn0038035). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:12399011..12401839. It has the cytological map location 87B9. Protein features are: BRCT domain; DNA ligase, ATP-dependent; DNA ligase, ATP-dependent, C-terminal; DNA ligase, ATP-dependent, N-terminal; DNA ligase, ATP-dependent, central; DNA ligase, ATP-dependent, conserved site; Nucleic acid-binding, OB-fold. Its molecular function is described by: DNA binding; DNA ligase (ATP) activity; ATP binding. It is involved in the biological process described with: DNA ligation involved in DNA repair; DNA biosynthetic process; DNA recombination. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; flight defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0038166	CG9588	-0.334127672	0.355349297	0.999936032	PSMD9	PSMD9	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG9588 (FBgn0038166). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:13675092..13676681. It has the cytological map location 87F7. Protein features are: 26S Proteasome non-ATPase regulatory subunit 9; PDZ domain. Its molecular function is unknown. It is involved in the biological process described with: cellular response to DNA damage stimulus; proteasome regulatory particle assembly. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed during early pupal stages.
FBgn0014143	croc	-0.333525521	0.427361155	0.999936032	NA	FOXC1;FOXC2;FOXS1	high;high;moderate	DNA-binding with transcription factor activity(Fork_head)	NA	NA	"The gene crocodile is referred to in FlyBase by the symbol Dmel\croc (CG5069, FBgn0014143). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:21474133..21476479. It has the cytological map location 78D3. Protein features are: Fork head domain; Fork head domain conserved site 2; Fork head domain conserved site1; Winged helix-turn-helix DNA-binding domain. Its molecular function is described by: sequence-specific DNA binding; DNA binding; RNA polymerase II transcription factor activity, sequence-specific DNA binding. It is involved in the biological process described with: cell differentiation; regulation of transcription, DNA-templated; specification of segmental identity, head; anatomical structure morphogenesis. 10 alleles are reported. The phenotypes of these alleles manifest in: sense organ; alimentary canal; embryonic/larval gut; embryonic/larval head nerve; hypopharynx; embryonic labral segment; larval tagma; embryonic/larval esophagus; embryonic/larval labral nerve; integumentary system; sensory organ cell. The phenotypic classes of alleles include: some die during embryonic stage; lethal - all die before end of embryonic stage; visible; viable; flight defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0036953	CG17145	-0.333148806	0.423975489	0.999936032	NA	MATN2	low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG17145 (FBgn0036953). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:20221814..20223197. It has the cytological map location 77A2. Protein features are: Chitin binding domain. Its molecular function is described by: chitin binding. It is involved in the biological process described with: chitin metabolic process. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the larval period.
FBgn0259935	CG42458	-0.332993187	0.425262429	0.999936032	NA	HNRNPC;RALY;HNRNPCL1;RALYL;HNRNPCL3;HNRNPCL2;HNRNPCL4	high;moderate;moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG42458 (FBgn0259935). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:7423827..7454717. It has the cytological map location 66A1. Protein features are: RNA recognition motif domain; WD40/YVTN repeat-like-containing domain; Zinc finger C2H2-type. Its molecular function is described by: mRNA binding; RNA binding. It is involved in the biological process described with: . 8 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; chaeta. The phenotypic classes of alleles include: viable; visible; short lived; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages.  "
FBgn0010265	RpS13	-0.332970212	0.323598391	0.999936032	NA	RPS13	high	NA	NA	NA	"The gene Ribosomal protein S13 is referred to in FlyBase by the symbol Dmel\RpS13 (CG13389, FBgn0010265). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:8363477..8364662. It has the cytological map location 29B2. Protein features are: Ribosomal protein S13/S15, N-terminal; Ribosomal protein S15; Ribosomal protein S15P; S15/NS1, RNA-binding. Its molecular function is described by: structural constituent of ribosome; small ribosomal subunit rRNA binding. It is involved in the biological process described with: translation; cytoplasmic translation. 13 alleles are reported. The phenotypes of these alleles manifest in: adult heart; macrochaeta; scutellar bristle; prothoracic gland. The phenotypic classes of alleles include: increased mortality during development; phenotype; increased mortality; developmental rate defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.  "
FBgn0021906	RFeSP	-0.332847524	0.322329848	0.999936032	NA	UQCRFS1;UQCRFS1P1	high;moderate	NA	transmembrane protein	NA	"The gene Rieske iron-sulfur protein is referred to in FlyBase by the symbol Dmel\RFeSP (CG7361, FBgn0021906). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:1612429..1614160. It has the cytological map location 22A3. Protein features are: Rieske [2Fe-2S] iron-sulphur domain; Rieske iron-sulphur protein; Rieske iron-sulphur protein, C-terminal; Ubiquinol cytochrome reductase, transmembrane domain; Ubiquinol-cytochrome c reductase, iron-sulphur subunit. Its molecular function is described by: ubiquinol-cytochrome-c reductase activity; 2 iron, 2 sulfur cluster binding. It is involved in the biological process described with: mitochondrial electron transport, ubiquinol to cytochrome c. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0034915	eIF6	-0.332807022	0.341258582	0.999936032	NA	EIF6	high	NA	NA	NA	"The gene eukaryotic translation initiation factor 6 is referred to in FlyBase by the symbol Dmel\eIF6 (CG17611, FBgn0034915). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:23849246..23850301. It has the cytological map location 60A3. Protein features are: Translation initiation factor IF6. Its molecular function is described by: ribosomal large subunit binding; ribosome binding; translation initiation factor activity. It is involved in the biological process described with: maturation of 5.8S rRNA; mature ribosome assembly; maturation of LSU-rRNA; translational initiation; ribosomal subunit export from nucleus; assembly of large subunit precursor of preribosome; cellular response to starvation. 7 alleles are reported. The phenotypes of these alleles manifest in: tarsal segment; sex comb; wing. The phenotypic classes of alleles include: visible; lethal; partially lethal; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed during early larval stages.  "
FBgn0031233	Tbc1d15-17	-0.332779367	0.37253873	0.999936032	TBC1D15	TBC1D15;TBC1D17	high;moderate	NA	NA	NA	"The gene TBC1 domain family member 15/17 is referred to in FlyBase by the symbol Dmel\Tbc1d15-17 (CG11490, FBgn0031233). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:207179..210725. It has the cytological map location 21B4. Protein features are: Rab-GTPase-TBC domain. Its molecular function is described by: Rab GTPase binding; GTPase activator activity. It is involved in the biological process described with: intracellular protein transport; activation of GTPase activity; regulation of vesicle fusion; regulation of GTPase activity. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0032198	eEF1delta	-0.332580386	0.331002571	0.999936032	EEF1D	EEF1D;EEF1B2	high;moderate	NA	NA	NA	"The gene eukaryotic translation elongation factor 1 delta is referred to in FlyBase by the symbol Dmel\eEF1‘Ç (CG4912, FBgn0032198). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:10232507..10234450. It has the cytological map location 31B1. Protein features are: Elongation factor 1 beta central acidic region, eukaryote; Translation elongation factor EF1B, beta/delta chains, conserved site; Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain; Translation elongation factor EF1B/ribosomal protein S6. Its molecular function is described by: translation elongation factor activity. It is involved in the biological process described with: translational elongation. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal - all die before end of pupal stage; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in adult female stages.  "
FBgn0003392	shi	-0.332567218	0.351596717	0.999936032	NA	DNM1;DNM2;DNM3;DNM1P34;DNM1L	high;moderate;moderate;moderate;low	NA	NA	NA	"The gene shibire is referred to in FlyBase by the symbol Dmel\shi (CG18102, FBgn0003392). It is a protein_coding_gene from Drosophila melanogaster. It has 15 annotated transcripts and 15 polypeptides (7 unique). Gene sequence location is X:15892116..15906716. It has the cytological map location 13F18. Protein features are: Dynamin GTPase effector; Dynamin central domain; Dynamin superfamily; Dynamin, GTPase domain; Dynamin, GTPase region, conserved site; Dynamin-1; Dynamin-2; Dynamin-type guanine nucleotide-binding (G) domain; GTPase effector domain; P-loop containing nucleoside triphosphate hydrolase; PH domain-like; Pleckstrin homology domain. Its molecular function is described by: GTPase activity; actin binding; microtubule binding; GTP binding. It is involved in the biological process described with 48 unique terms, many of which group under: exocrine system development; cellular protein localization; extracellular structure organization; cellular protein metabolic process; positive regulation of protein complex assembly; reflex; growth; adherens junction organization; dorsal appendage formation; retinal cell programmed cell death. 93 alleles are reported. The phenotypes of these alleles manifest in: synapse; organelle part; embryonic/larval tracheal system; sensory mother cell; ensheathing neuropil associated glial cell; membrane region; trachea; cortical actin cytoskeleton; macrophage; border follicle cell; sensillum coeloconicum of antennal segment 3; neuron projection; rhabdomere; embryonic foregut; neuroblast; dorsal appendage. The phenotypic classes of alleles include: mating defective; phenotype; sensory perception defective; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0026872	CG14777	-0.3324947	0.336802655	0.999936032	NA	MPV17L	moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14777 (FBgn0026872). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is X:1466134..1468692. It has the cytological map location 2A4. Protein features are: Mpv17/PMP22. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0030053	CG12081	-0.332466241	0.362987896	0.999936032	KLHDC3	KLHDC3;FBXO42;RABEPK	high;low;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12081 (FBgn0030053). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:8588811..8590774. It has the cytological map location 7F7. Protein features are: Galactose oxidase/kelch, beta-propeller; Kelch repeat type 1; Kelch-type beta propeller. Its molecular function is described by: chromatin binding. It is involved in the biological process described with: . 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, during late pupal stages.  "
FBgn0052380	SMSr	-0.332329923	0.412801442	0.999936032	NA	SAMD8;SGMS2;SGMS1	high;moderate;moderate	NA	transmembrane protein	NA	"The gene SMSr is referred to in FlyBase by the symbol Dmel\SMSr (CG32380, FBgn0052380). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:7374050..7381474. It has the cytological map location 65F7-65F9. Protein features are: Sphingomyelin synthase-like domain; Sterile alpha motif domain; Sterile alpha motif/pointed domain. Its molecular function is described by: ceramide cholinephosphotransferase activity; sphingomyelin synthase activity. It is involved in the biological process described with: regulation of cell diameter; ceramide biosynthetic process; Golgi organization; sphingomyelin biosynthetic process; regulation of ceramide biosynthetic process. 12 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0002772	Mlc1	-0.331830597	0.328309409	0.999936032	NA	MYL4;MYL6B;MYL1;MYL3;MYL6	moderate;moderate;moderate;moderate;low	NA	NA	NA	"The gene Myosin alkali light chain 1 is referred to in FlyBase by the symbol Dmel\Mlc1 (CG5596, FBgn0002772). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:27657078..27660177. It has the cytological map location 98A14-98A15. Protein features are: EF-hand domain; EF-hand domain pair. Its molecular function is described by: microfilament motor activity; calcium ion binding. It is involved in the biological process described with: mesoderm development; muscle contraction. 4 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: lethal - all die during P-stage; viable; visible; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0032116	Mco1	-0.33169747	0.355002264	0.999936032	NA	HEPHL1;CP;HEPH	high;high;high	NA	NA	NA	"The gene Multicopper oxidase-1 is referred to in FlyBase by the symbol Dmel\Mco1 (CG3759, FBgn0032116). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:9416588..9426342. It has the cytological map location 30B2-30B3. Protein features are: Cupredoxin; Multicopper oxidase, copper-binding site; Multicopper oxidase, type 1; Multicopper oxidase, type 2; Multicopper oxidase, type 3; Multicopper oxidases, conserved site. Its molecular function is described by: copper ion binding; ferroxidase activity; iron ion transmembrane transporter activity. It is involved in the biological process described with: iron assimilation by reduction and transport; iron ion transport; oxidation-reduction process; iron ion homeostasis. 5 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum. The phenotypic classes of alleles include: body color defective; viable; visible; chemical resistant. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0086361	alph	-0.33163898	0.338232737	0.999936032	NA	PPM1A;PPM1B;PPM1N	high;moderate;moderate	NA	NA	NA	"The gene alphabet is referred to in FlyBase by the symbol Dmel\alph (CG1906, FBgn0086361). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (4 unique). Gene sequence location is 3R:29591831..29617157. It has the cytological map location 99B4-99B5. Protein features are: PPM-type phosphatase domain; PPM-type phosphatase, divalent cation binding; Protein phosphatase 2C family; Protein serine/threonine phosphatase 2C, C-terminal. Its molecular function is described by: magnesium ion binding; manganese ion binding; phosphatase activity; protein serine/threonine phosphatase activity. It is involved in the biological process described with 19 unique terms, many of which group under: morphogenesis of embryonic epithelium; multicellular organism aging; positive regulation of photoreceptor cell differentiation; response to paraquat; response to abiotic stimulus; imaginal disc-derived appendage development; response to oxidative stress; photoreceptor cell differentiation; response to chemical; response to light stimulus; protein dephosphorylation. 19 alleles are reported. The phenotypes of these alleles manifest in: cone cell; tertiary pigment cell; secondary pigment cell; primary pigment cell; photoreceptor cell R7. The phenotypic classes of alleles include: increased mortality; phenotype; viable; wild-type; semi-sterile; long lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0016078	wun	-0.331337137	0.342319419	0.999936032	NA	PLPP1;PLPP3;PLPP2;PLPPR2;PLPP4;PLPP5	high;moderate;moderate;moderate;low;low	NA	transmembrane protein	NA	"The gene wunen is referred to in FlyBase by the symbol Dmel\wun (CG8804, FBgn0016078). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 2R:9400531..9413463. It has the cytological map location 45D3-45D4. Protein features are: Phosphatidic acid phosphatase type 2/haloperoxidase. Its molecular function is described by: lipid phosphatase activity; phosphatidate phosphatase activity; protein homodimerization activity; phosphatase activity. It is involved in the biological process described with 13 unique terms, many of which group under: metabolic process; response to stimulus; cell junction assembly; immune response; open tracheal system development; cellular developmental process; response to external biotic stimulus; anatomical structure development; cell-cell junction organization; response to bacterium; regulation of defense response; cellular response to chemical stimulus. 50 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval transverse connective; intersegmental nerve; embryonic/larval lateral trunk; embryonic/larval dorsal trunk; germline cell; synapse; bouton. The phenotypic classes of alleles include: behavior defective; wild-type; increased mortality; fertile; viable; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 12-18 embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0034143	CG8303	-0.331253861	0.39683048	0.999936032	NA	FAR2;FAR1	moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8303 (FBgn0034143). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:16595028..16604373. It has the cytological map location 53C9-53C10. Protein features are: Fatty acyl-CoA reductase; Fatty acyl-CoA reductase, C-terminal; Male sterility, NAD-binding; NAD(P)-binding domain. Its molecular function is described by: fatty-acyl-CoA reductase (alcohol-forming) activity; long-chain-fatty-acyl-CoA reductase activity. It is involved in the biological process described with: long-chain fatty-acyl-CoA metabolic process; wax biosynthetic process. 13 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0036778	Cyp312a1	-0.331253861	0.39683048	0.999936032	NA	CYP4V2;CYP4A11;CYP4Z1;CYP4B1;CYP4F11;CYP4X1;CYP4F12;CYP4A22	moderate;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene Cyp312a1 is referred to in FlyBase by the symbol Dmel\Cyp312a1 (CG5137, FBgn0036778). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:18128940..18132689. It has the cytological map location 75B11. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group IV. Its molecular function is described by: monooxygenase activity; heme binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; iron ion binding. It is involved in the biological process described with: oxidation-reduction process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed in adult male stages.  "
FBgn0266518	Dpit47	-0.330880148	0.354351113	0.999936032	NA	TTC4	high	NA	NA	NA	"The gene DNA polymerase interacting tpr containing protein of 47kD is referred to in FlyBase by the symbol Dmel\Dpit47 (CG3189, FBgn0266518). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:6660645..6662118. It has the cytological map location 42C3. Protein features are: Tetratricopeptide repeat; Tetratricopeptide repeat-containing domain; Tetratricopeptide-like helical domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable."
FBgn0033234	MFS12	-0.330816386	0.285168316	0.999936032	NA	SLC17A5;SLC17A4;SLC17A3;SLC17A2;SLC17A1;SLC17A6;SLC17A8;SLC17A7	moderate;high;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene Major Facilitator Superfamily Transporter 12 is referred to in FlyBase by the symbol Dmel\MFS12 (CG8791, FBgn0033234). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2R:7926653..7929922. It has the cytological map location 43F2. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain. Its molecular function is described by: transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; anion transport. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during early pupal stages.  "
FBgn0035755	CG14830	-0.330511616	0.424948202	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14830 (FBgn0035755). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3L:7250718..7263920. It has the cytological map location 65E9-65E10. Its molecular function is unknown. The biological processes in which it is involved are not known. 8 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during late pupal stages.  "
FBgn0037549	CG7878	-0.330045948	0.356618754	0.999936032	DDX43	DDX43;DDX53	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7878 (FBgn0037549). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:8122725..8125273. It has the cytological map location 84E13. Protein features are: ATP-dependent RNA helicase DEAD-box, conserved site; DEAD/DEAH box helicase domain; Helicase superfamily 1/2, ATP-binding domain; Helicase, C-terminal; K Homology domain; K Homology domain, type 1; P-loop containing nucleoside triphosphate hydrolase; RNA helicase, DEAD-box type, Q motif. Its molecular function is described by: ATP binding; ATP-dependent RNA helicase activity; RNA binding; helicase activity. It is involved in the biological process described with: RNA secondary structure unwinding. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0039714	Zip99C	-0.329840595	0.34241152	0.999936032	NA	SLC39A13	high	NA	transmembrane protein	NA	"The gene Zinc/iron regulated transporter-related protein 99C is referred to in FlyBase by the symbol Dmel\Zip99C (CG7816, FBgn0039714). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (1 unique). Gene sequence location is 3R:29863701..29868895. It has the cytological map location 99C4-99C5. Protein features are: Zinc/iron permease. Its molecular function is described by: zinc ion transmembrane transporter activity; iron ion transmembrane transporter activity. It is involved in the biological process described with: multicellular organismal iron ion homeostasis; detoxification of zinc ion; iron ion transport; cellular zinc ion homeostasis; zinc II ion transmembrane transport. 12 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: pain response defective; partially lethal - majority die; majority die during pupal stage; viable; short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed during late larval stages, during early pupal stages, in adult male stages.  "
FBgn0035977	PGRP-LF	-0.329665279	0.424489423	0.999936032	NA	PGLYRP3;PGLYRP4;PGLYRP1	high;moderate;low	NA	transmembrane protein	NA	"The gene Peptidoglycan recognition protein LF is referred to in FlyBase by the symbol Dmel\PGRP-LF (CG4437, FBgn0035977). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:9349609..9351489. It has the cytological map location 67B1. Protein features are: N-acetylmuramoyl-L-alanine amidase domain; Peptidoglycan recognition protein; Peptidoglycan recognition protein family domain, metazoa/bacteria. Its molecular function is described by: peptidoglycan binding; N-acetylmuramoyl-L-alanine amidase activity; zinc ion binding. It is involved in the biological process described with: peptidoglycan recognition protein signaling pathway; determination of adult lifespan; negative regulation of JNK cascade; defense response to other organism; antibacterial humoral response; peptidoglycan catabolic process; response to bacterium. 9 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: visible; partially lethal - majority die; immune response defective; long lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during early pupal stages, in adult male stages.  "
FBgn0264694	mgr	-0.329652313	0.346901857	0.999936032	NA	VBP1	high	NA	NA	NA	"The gene merry-go-round is referred to in FlyBase by the symbol Dmel\mgr (CG6719, FBgn0264694). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:11408792..11409875. It has the cytological map location 86E4. Protein features are: Prefoldin alpha-like; Prefoldin subunit 3. Its molecular function is described by: beta-tubulin binding. It is involved in the biological process described with: microtubule-based process; mitotic spindle assembly; centrosome cycle; spindle assembly involved in meiosis; establishment or maintenance of neuroblast polarity; tubulin complex assembly; protein folding. 10 alleles are reported. The phenotypes of these alleles manifest in: somatic stem cell; somatic precursor cell; material anatomical entity; single-organism process; microtubule; mechanosensory system; larval tagma; germline cyst; cell cycle; adult. The phenotypic classes of alleles include: visible; phenotype; increased mortality; cell cycle defective; sterile."
FBgn0010438	mtSSB	-0.329576301	0.379115221	0.999936032	SSBP1	SSBP1	high	NA	NA	NA	"The gene mitochondrial single stranded DNA-binding protein is referred to in FlyBase by the symbol Dmel\mtSSB (CG4337, FBgn0010438). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:16204194..16205250. It has the cytological map location 89B7. Protein features are: Nucleic acid-binding, OB-fold; Primosome PriB/single-strand DNA-binding; Single-stranded DNA-binding protein. Its molecular function is described by: single-stranded DNA binding. It is involved in the biological process described with: mitochondrial genome maintenance; mitochondrial DNA replication. 16 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: wild-type; cell growth defective; lethal; fertile; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0017545	RpS3A	-0.329487664	0.325080642	0.999936032	NA	RPS3A	high	NA	NA	NA	"The gene Ribosomal protein S3A is referred to in FlyBase by the symbol Dmel\RpS3A (CG2168, FBgn0017545). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 4:65225..67207. It has the cytological map location 101F1. Protein features are: 40S ribosomal protein S1/3, eukaryotes; Ribosomal protein S3Ae; Ribosomal protein S3Ae, conserved site. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; translation. 10 alleles are reported. The phenotypes of these alleles manifest in: nurse cell; adult; follicle cell; egg chamber; adult heart; macrochaeta. The phenotypic classes of alleles include: size defective; Minute; increased mortality during development; phenotype; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages.  "
FBgn0034294	Muc55B	-0.329466791	0.371486833	0.999936032	NA	PRR21;KHDC3L;CLEC4F	low;low;low	NA	NA	NA	"The gene Mucin 55B is referred to in FlyBase by the symbol Dmel\Muc55B (CG5765, FBgn0034294). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:18050019..18052107. It has the cytological map location 55B2. Protein features are: Protein of unknown function DUF725. Its molecular function is described by: extracellular matrix structural constituent. It is involved in the biological process described with: . 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0032763	CG17568	-0.329405599	0.431076295	0.999936032	NA	ZNF671;ZNF667;ZNF662;ZNF763;ZNF865;ZNF212;ZNF783	low;low;low;low;low;low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17568 (FBgn0032763). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:19179749..19181702. It has the cytological map location 37C6. Protein features are: Zinc finger C2H2-type; Zinc finger, AD-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: nucleic acid binding; zinc ion binding. The biological processes in which it is involved are not known. 11 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0013718	nuf	-0.329368903	0.3982713	0.999936032	NA	RAB11FIP4;RAB11FIP3	high;moderate	NA	NA	NA	"The gene nuclear fallout is referred to in FlyBase by the symbol Dmel\nuf (CG33991, FBgn0013718). It is a protein_coding_gene from Drosophila melanogaster. It has 12 annotated transcripts and 12 polypeptides (9 unique). Gene sequence location is 3L:14190870..14233250. It has the cytological map location 70D3-70D4. Protein features are: Rab-binding domain FIP-RBD. Its molecular function is described by: microtubule binding. It is involved in the biological process described with: actin cytoskeleton reorganization; microtubule-based process; wing disc dorsal/ventral pattern formation; actomyosin contractile ring assembly; sensory organ precursor cell fate determination. 51 alleles are reported. The phenotypes of these alleles manifest in: cell part; actin cytoskeleton; cell surface; nervous system; M phase; embryo; intracellular; intracellular organelle; sensory organ cell; organelle. The phenotypic classes of alleles include: lethal - all die before end of larval stage; increased mortality; phenotype; viable; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0036299	Tsf2	-0.329286925	0.432665726	0.999936032	MFI2	MELTF;TF;LTF	high;moderate;moderate	NA	NA	NA	"The gene Transferrin 2 is referred to in FlyBase by the symbol Dmel\Tsf2 (CG10620, FBgn0036299). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:12530436..12533724. It has the cytological map location 69C4-69C5. Protein features are: Transferrin; Transferrin family, iron binding site; Transferrin-like domain. Its molecular function is described by: iron ion binding. It is involved in the biological process described with: septate junction assembly. 13 alleles are reported. The phenotypes of these alleles manifest in: septate junction; embryonic/larval dorsal trunk. The phenotypic classes of alleles include: viable; lethal - all die before end of larval stage; lethal; partially lethal; some die during larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 06-18 hour embryonic stages.  "
FBgn0035696	Best2	-0.329268327	0.42421143	0.999936032	NA	BEST3;BEST4;BEST1;BEST2	moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene Bestrophin 2 is referred to in FlyBase by the symbol Dmel\Best2 (CG10173, FBgn0035696). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:6245933..6256665. It has the cytological map location 65A10. Protein features are: Bestrophin; Bestrophin/UPF0187. Its molecular function is described by: chloride channel activity. It is involved in the biological process described with: chloride transport. 10 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0023540	CG3630	-0.329237575	0.327959829	0.999936032	NA	ABRA	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG3630 (FBgn0023540). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is X:2162196..2172281. It has the cytological map location 2D6. Protein features are: Actin-binding Rho-activating protein; Costars domain. Its molecular function is described by: actin binding. It is involved in the biological process described with: positive regulation of Rho protein signal transduction. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; memory defective; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late pupal stages.
FBgn0029148	NHP2	-0.329134236	0.340978237	0.999936032	NA	NHP2	high	NA	NA	NA	"The gene NHP2 is referred to in FlyBase by the symbol Dmel\NHP2 (CG5258, FBgn0029148). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:14801328..14802168. It has the cytological map location 70F6. Protein features are: 50S ribosomal protein L30e-like; Ribosomal protein L7Ae/L30e/S12e/Gadd45; Ribosomal protein L7Ae/L8/Nhp2 family. Its molecular function is described by: snoRNA binding; box H/ACA snoRNA binding. It is involved in the biological process described with: translation; rRNA pseudouridine synthesis; cleavage involved in rRNA processing; maturation of LSU-rRNA; cellular response to starvation; snRNA pseudouridine synthesis. 5 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; lethal - all die during P-stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages.  "
FBgn0037288	CG14661	-0.328725065	0.430935403	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG14661 (FBgn0037288). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:4953506..4955252. It has the cytological map location 82E4. Protein features are: Haemolymph juvenile hormone binding. Its molecular function is unknown. It is involved in the biological process described with: circadian rhythm; multicellular organism reproduction. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed in adult male stages.
FBgn0260458	PGRP-LD	-0.328605326	0.434167873	0.999936032	NA	PGLYRP1;PGLYRP2;PGLYRP3;PGLYRP4	moderate;low;low;low	NA	transmembrane protein	NA	"The gene Peptidoglycan recognition protein LD is referred to in FlyBase by the symbol Dmel\PGRP-LD (CG33717, FBgn0260458). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3L:5780051..5784685. It has the cytological map location 64E7-64E8. Protein features are: N-acetylmuramoyl-L-alanine amidase domain; Peptidoglycan recognition protein; Peptidoglycan recognition protein family domain, metazoa/bacteria. Its molecular function is described by: zinc ion binding; peptidoglycan binding. It is involved in the biological process described with: peptidoglycan catabolic process; immune response; innate immune response. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 12-18 embryonic stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0023180	Orc6	-0.328441747	0.403108528	0.999936032	NA	ORC6	high	NA	NA	NA	"The gene Origin recognition complex subunit 6 is referred to in FlyBase by the symbol Dmel\Orc6 (CG1584, FBgn0023180). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:9845458..9846485. It has the cytological map location 46B4. Protein features are: Origin recognition complex, subunit 6; Origin recognition complex, subunit 6, metazoa/plant. Its molecular function is described by: protein homodimerization activity; GTPase activator activity; DNA replication origin binding. It is involved in the biological process described with: mitotic cell cycle; septin cytoskeleton organization; DNA replication; DNA replication initiation; positive regulation of GTPase activity. 14 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval optic lobe; presumptive embryonic salivary gland; embryonic/larval brain; trichogen cell; imaginal disc. The phenotypic classes of alleles include: visible; phenotype; increased mortality during development; viable; lethal; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0014073	Tie	-0.32838695	0.424976266	0.999936032	NA	TYRO3;MERTK;AXL;LMTK3;TEK;FGFR4;KDR;RET;PDGFRL;PDGFRA;FLT3;FGFR1;FGFR3;STYK1;FLT4;FGFR2;FLT1;TIE1;KIT;FGFRL1;PDGFRB;CSF1R	low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene Tie-like receptor tyrosine kinase is referred to in FlyBase by the symbol Dmel\Tie (CG7525, FBgn0014073). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:4510698..4532145. It has the cytological map location 64B9. Protein features are: Protein kinase domain; Protein kinase, ATP binding site; Protein kinase-like domain; Serine-threonine/tyrosine-protein kinase, catalytic domain; Tyrosine-protein kinase, active site; Tyrosine-protein kinase, catalytic domain. Its molecular function is described by: protein tyrosine kinase activity; ATP binding. It is involved in the biological process described with: regulation of cellular response to X-ray; border follicle cell migration; negative regulation of cell death; peptidyl-tyrosine phosphorylation; protein phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway. 15 alleles are reported. The phenotype of these alleles manifest in: female germline stem cell. The phenotypic classes of alleles include: radiation sensitive; fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during late pupal stages.  "
FBgn0263740	eIF2gamma	-0.328301829	0.337035821	0.999936032	NA	EIF2S3;SUV39H2;SUV39H1	high;moderate;moderate	Chromatin regulation	NA	NA	"The gene eukaryotic translation initiation factor 2 subunit gamma is referred to in FlyBase by the symbol Dmel\eIF2‘_ (CG43665, FBgn0263740). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:15257844..15263458. It has the cytological map location 88E6-88E8. Protein features are: P-loop containing nucleoside triphosphate hydrolase; Transcription factor, GTP-binding domain; Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal; Translation elongation factor EFTu-like, domain 2; Translation initiation factor 2, gamma subunit, C-terminal; Translation protein, beta-barrel domain. Its molecular function is described by: GTPase activity; translation initiation factor activity; GTP binding. It is involved in the biological process described with: formation of translation preinitiation complex. 9 alleles are reported. No phenotypic data is available. No phenotypic class data is available."
FBgn0000409	Cyt-c-p	-0.328264302	0.328006625	0.999936032	NA	CYCS	high	NA	NA	NA	NA
FBgn0035811	CG12262	-0.328034122	0.331050918	0.999936032	ACADM	ACADM;ACAD8	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12262 (FBgn0035811). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:7719350..7721472. It has the cytological map location 66A10. Protein features are: Acyl-CoA dehydrogenase, conserved site; Acyl-CoA dehydrogenase/oxidase C-terminal; Acyl-CoA dehydrogenase/oxidase, N-terminal; Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain; Acyl-CoA oxidase/dehydrogenase, central domain; Medium-chain specific acyl-CoA dehydrogenase. Its molecular function is described by: flavin adenine dinucleotide binding; acyl-CoA dehydrogenase activity; medium-chain-acyl-CoA dehydrogenase activity. It is involved in the biological process described with: fatty acid beta-oxidation. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in stages of adults of both sexes.  "
FBgn0028342	ATPsyndelta	-0.328025633	0.331884819	0.999936032	NA	ATP5D	high	NA	NA	NA	"The gene ATP synthase, ‘Ç subunit is referred to in FlyBase by the symbol Dmel\ATPsyn‘Ç (CG2968, FBgn0028342). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is X:10212970..10217393. It has the cytological map location 9B4. Protein features are: ATP synthase delta/epsilon subunit, C-terminal domain; ATP synthase, F1 complex, delta/epsilon subunit; ATP synthase, F1 complex, delta/epsilon subunit, N-terminal. Its molecular function is described by: proton-transporting ATP synthase activity, rotational mechanism. It is involved in the biological process described with: proton transport; ATP synthesis coupled proton transport. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0000721	for	-0.327586674	0.365948354	0.999936032	NA	PRKG1;PRKG2	high;moderate	NA	NA	NA	"The gene foraging is referred to in FlyBase by the symbol Dmel\for (CG10033, FBgn0000721). It is a protein_coding_gene from Drosophila melanogaster. It has 10 annotated transcripts and 10 polypeptides (4 unique). Gene sequence location is 2L:3622074..3656953. It has the cytological map location 24A2-24A4. Protein features are: AGC-kinase, C-terminal; Cyclic nucleotide-binding domain; Cyclic nucleotide-binding, conserved site; Cyclic nucleotide-binding-like; Protein kinase domain; Protein kinase, ATP binding site; Protein kinase-like domain; RmlC-like jelly roll fold; Serine/threonine-protein kinase, active site; cGMP-dependent kinase; cGMP-dependent protein kinase, N-terminal coiled-coil domain; cGMP-dependent protein kinase, catalytic domain. Its molecular function is described by: cyclic nucleotide-dependent protein kinase activity; cGMP-dependent protein kinase activity; protein serine/threonine kinase activity; ATP binding. It is involved in the biological process described with 12 unique terms, many of which group under: feeding behavior; behavior; circulatory system process; response to food; transmembrane receptor protein serine/threonine kinase signaling pathway; response to oxygen-containing compound; neuron differentiation; protein modification process; cell part morphogenesis; heart process; short-term memory; learning; regulation of response to external stimulus; regulation of macromolecule metabolic process. 100 alleles are reported. The phenotypes of these alleles manifest in: crystal cell; axon terminus; axon; embryonic/larval tracheal system; wing blade; mesothoracic tergum; adult heart; intersegmental nerve branch ISNb of A1-7; adult Malpighian tubule; eye. The phenotypic classes of alleles include: behavior defective; increased mortality; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0004237	Hrb87F	-0.327523229	0.362392462	0.999936032	NA	HNRNPA2B1;HNRNPA1L2;HNRNPA3;HNRNPA1;HNRNPA0;MIR4444-1;HNRNPAB;DAZAP1;HNRNPD	moderate;moderate;moderate;moderate;moderate;moderate;low;low;low	NA	NA	NA	"The gene Heterogeneous nuclear ribonucleoprotein at 87F is referred to in FlyBase by the symbol Dmel\Hrb87F (CG12749, FBgn0004237). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 3R:13656846..13660531. It has the cytological map location 87F7. Protein features are: RNA recognition motif domain. Its molecular function is described by: mRNA binding; sequence-specific DNA binding. It is involved in the biological process described with: regulation of alternative mRNA splicing, via spliceosome; compound eye morphogenesis; response to starvation; female gonad development; response to heat; mitotic cell cycle. 19 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval neuroblast; ganglion mother cell. The phenotypic classes of alleles include: viable; lethal; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.  "
FBgn0262742	Fas1	-0.327338703	0.436059975	0.999936032	NA	POSTN;TGFBI	moderate;moderate	NA	NA	NA	NA
FBgn0261477	slim	-0.32720764	0.389325807	0.999936032	NA	KLHDC10	high	NA	NA	NA	"The gene scruin like at the midline is referred to in FlyBase by the symbol Dmel\slim (CG5186, FBgn0261477). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:18440965..18445526. It has the cytological map location 55C9. Protein features are: Galactose oxidase, beta-propeller; Kelch repeat type 1; Kelch-type beta propeller. Its molecular function is described by: . It is involved in the biological process described with: positive regulation of stress-activated MAPK cascade. 11 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval somatic muscle; trichogen cell; sarcomere; adult cuticle; ovariole; mesothoracic tergum. The phenotypic classes of alleles include: increased mortality during development; phenotype; visible; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, in adult male stages.  "
FBgn0031904	CG5149	-0.327187237	0.360133999	0.999936032	NA	TLDC1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5149 (FBgn0031904). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:7384486..7388253. It has the cytological map location 27F3. Protein features are: Claudin, conserved site; TLDc domain. Its molecular function is described by: structural molecule activity. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0038876	CG5919	-0.327169113	0.395390188	0.999936032	IDI1	IDI1;IDI2	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5919 (FBgn0038876). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:21270126..21271408. It has the cytological map location 93D2. Protein features are: Isopentenyl-diphosphate delta-isomerase, type 1; NUDIX hydrolase domain; NUDIX hydrolase domain-like. Its molecular function is described by: isopentenyl-diphosphate delta-isomerase activity; hydrolase activity. It is involved in the biological process described with: isoprenoid biosynthetic process; isopentenyl diphosphate biosynthetic process. 5 alleles are reported. The phenotype of these alleles manifest in: tormogen cell. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 12-18 embryonic stages.  "
FBgn0259682	Jabba	-0.327025184	0.432918943	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene Jabba is referred to in FlyBase by the symbol Dmel\Jabba (CG42351, FBgn0259682). It is a protein_coding_gene from Drosophila melanogaster. It has 8 annotated transcripts and 8 polypeptides (7 unique). Gene sequence location is 2R:18757074..18761082. It has the cytological map location 55F1. Protein features are: Protein of unknown function DUF4820. Its molecular function is described by: . It is involved in the biological process described with: . 15 alleles are reported. The phenotype of these alleles manifest in: lipid particle. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0031906	CG5160	-0.326981838	0.436151412	0.999936032	NA	RASL11B;RASL11A;RERGL	moderate;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5160 (FBgn0031906). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:7390984..7398750. It has the cytological map location 27F3. Protein features are: P-loop containing nucleoside triphosphate hydrolase; Small GTPase superfamily; Small GTPase superfamily, Ras type. Its molecular function is described by: GTPase activity; GTP binding. It is involved in the biological process described with: signal transduction. 6 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; ganglion mother cell. The phenotypic classes of alleles include: increased mortality; lethal; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult male stages.  "
FBgn0033836	CG18278	-0.326632088	0.384336414	0.999936032	NA	GNS;SULF1	high;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG18278 (FBgn0033836). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:13408042..13409887. It has the cytological map location 50A5. Protein features are: Alkaline phosphatase-like, alpha/beta/alpha; Alkaline-phosphatase-like, core domain; N-acetylglucosamine-6-sulfatase; Sulfatase, N-terminal; Sulfatase, conserved site. Its molecular function is described by: N-acetylglucosamine-6-sulfatase activity. It is involved in the biological process described with: glycosaminoglycan metabolic process. 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0030228	BTBD9	-0.326495152	0.408124816	0.999936032	BTBD9	BTBD9	high	NA	NA	NA	"The gene BTB (POZ) domain containing 9 is referred to in FlyBase by the symbol Dmel\BTBD9 (CG1826, FBgn0030228). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:10768537..10772154. It has the cytological map location 9E7-9E8. Protein features are: BTB/Kelch-associated; BTB/POZ domain; BTBD9, BACK-like domain; Coagulation factor 5/8 C-terminal domain; Galactose-binding domain-like; SKP1/BTB/POZ domain. Its molecular function is described by: ubiquitin protein ligase binding; protein binding, bridging. It is involved in the biological process described with: proteasome-mediated ubiquitin-dependent protein catabolic process; positive regulation of circadian sleep/wake cycle, sleep; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; adult locomotory behavior; regulation of proteolysis; regulation of synaptic transmission, dopaminergic. 12 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; short lived; partially lethal; locomotor behavior defective; sleep defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0037686	RpL34b	-0.326446922	0.339411034	0.999936032	NA	RPL34	high	NA	NA	NA	"The gene Ribosomal protein L34b is referred to in FlyBase by the symbol Dmel\RpL34b (CG9354, FBgn0037686). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 3R:9400237..9401226. It has the cytological map location 85D15. Protein features are: Ribosomal protein L34Ae; Ribosomal protein L34e, conserved site. Its molecular function is described by: RNA binding; structural constituent of ribosome. It is involved in the biological process described with: ribosome biogenesis; cytoplasmic translation; translation. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Very high expression at all stages of development.  "
FBgn0029507	Tsp42Ed	-0.326294833	0.330834483	0.999936032	NA	CD63	moderate	NA	transmembrane protein	NA	"The gene Tetraspanin 42Ed is referred to in FlyBase by the symbol Dmel\Tsp42Ed (CG12846, FBgn0029507). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:7009498..7011739. It has the cytological map location 42E5. Protein features are: Tetraspanin; Tetraspanin, EC2 domain; Tetraspanin, conserved site; Tetraspanin/Peripherin. Its molecular function is described by: . It is involved in the biological process described with: cell surface receptor signaling pathway. 9 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in adult male stages.  "
FBgn0036502	CG7841	-0.326277415	0.375220941	0.999936032	NA	MCRIP2;MCRIP1	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7841 (FBgn0036502). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:15505188..15508252. It has the cytological map location 71D3. Protein features are: Mapk-regulated corepressor-interacting protein. Its molecular function is described by: . It is involved in the biological process described with: . 8 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0259938	cwo	-0.326254546	0.347810648	0.999936032	NA	HES1;HES4;BHLHE41;HES6;HES2;BHLHE40;HELT	moderate;moderate;high;moderate;moderate;high;high	DNA-binding with transcription factor activity(HLH)	NA	NA	"The gene clockwork orange is referred to in FlyBase by the symbol Dmel\cwo (CG17100, FBgn0259938). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:10388258..10400752. It has the cytological map location 86B3. Protein features are: Myc-type, basic helix-loop-helix (bHLH) domain; Orange domain. Its molecular function is described by: transcription factor activity, sequence-specific DNA binding; DNA binding; protein dimerization activity. It is involved in the biological process described with: peripheral nervous system development; regulation of circadian rhythm; regulation of transcription, DNA-templated; negative regulation of transcription from RNA polymerase II promoter; dendrite morphogenesis; circadian regulation of gene expression. 23 alleles are reported. The phenotypes of these alleles manifest in: abdominal anterior ventral multidendritic neuron vdaa; dorsal multidendritic neuron ddaD; dorsal multidendritic neuron ddaC; wing. The phenotypic classes of alleles include: increased mortality; circadian rhythm defective; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0033485	RpLP0-like	-0.325959195	0.352953378	0.999936032	MRTO4	MRTO4	high	NA	NA	NA	"The gene Ribosomal protein LP0-like is referred to in FlyBase by the symbol Dmel\RpLP0-like (CG1381, FBgn0033485). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:10098518..10099590. It has the cytological map location 46E5-46E6. Protein features are: Ribosomal protein L10P; Ribosome assembly factor Mrt4. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: rRNA processing; cytoplasmic translation; nuclear-transcribed mRNA catabolic process; ribosomal large subunit assembly; translation. 4 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed during early larval stages.  "
FBgn0265991	Zasp52	-0.325833254	0.377418976	0.999936032	NA	PDLIM7;LDB3;PDLIM5;LPXN;PDLIM3;PDLIM1;PDLIM4	high;high;moderate;low;moderate;moderate;moderate	NA	NA	NA	"The gene Z band alternatively spliced PDZ-motif protein 52 is referred to in FlyBase by the symbol Dmel\Zasp52 (CG30084, FBgn0265991). It is a protein_coding_gene from Drosophila melanogaster. It has 21 annotated transcripts and 21 polypeptides (20 unique). Gene sequence location is 2R:15762565..15817004. It has the cytological map location 52C4-52C7. Protein features are: Domain of unknown function DUF4749; EF-Hand 1, calcium-binding site; PDZ domain; WD40/YVTN repeat-like-containing domain; Zasp-like motif; Zinc finger, LIM-type. Its molecular function is described by: actinin binding; muscle alpha-actinin binding; actin binding. It is involved in the biological process described with: myofibril assembly; regulation of cell-matrix adhesion; muscle structure development. 31 alleles are reported. The phenotypes of these alleles manifest in: H zone; indirect flight muscle; embryonic somatic muscle; M band; myofibril; visceral muscle fiber; embryonic/larval somatic muscle; Z disc. The phenotypic classes of alleles include: phenotype; increased mortality during development; lethal; increased mortality."
FBgn0037116	Als2	-0.325491884	0.408720707	0.999936032	NA	ALS2;ALS2CL;MORN4	high;moderate;low	NA	NA	NA	"The gene Amyotrophic lateral sclerosis 2 is referred to in FlyBase by the symbol Dmel\Als2 (CG7158, FBgn0037116). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:21674394..21679755. It has the cytological map location 78E3. Protein features are: MORN motif; PH domain-like; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; Regulator of chromosome condensation, RCC1; VPS9 domain. Its molecular function is described by: Rab guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: regulation of GTPase activity; regulation of Rab protein signal transduction; melanotic encapsulation of foreign target; positive regulation of GTPase activity. 9 alleles are reported. The phenotypes of these alleles manifest in: NMJ bouton; mesothoracic tergum. The phenotypic classes of alleles include: viable; visible; fertile; gravitaxis defective; immune response defective; locomotor behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.  "
FBgn0261545	CG42663	-0.325491884	0.408720707	0.999936032	NA	NCKAP5	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG42663 (FBgn0261545). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 2R:12705172..12751545. It has the cytological map location 49C1. Protein features are: Nck-associated protein 5-like. Its molecular function is unknown. It is involved in the biological process described with: determination of adult lifespan. 9 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: partially lethal - majority die; long lived; lethal; visible; lethal - all die during P-stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the pupal period.  "
FBgn0267385	PyK	-0.325484258	0.334325064	0.999936032	NA	PKM;PKLR	high;moderate	NA	NA	NA	"The gene Pyruvate kinase is referred to in FlyBase by the symbol Dmel\PyK (CG7070, FBgn0267385). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:22367536..22372746. It has the cytological map location 94A9-94A6. Protein features are: Pyruvate kinase; Pyruvate kinase, C-terminal; Pyruvate kinase, active site; Pyruvate kinase, barrel; Pyruvate kinase-like, insert domain; Pyruvate/Phosphoenolpyruvate kinase-like domain. Its molecular function is described by: magnesium ion binding; potassium ion binding; pyruvate kinase activity. It is involved in the biological process described with: glycolytic process; somatic muscle development; regulation of glucose metabolic process; response to sucrose; myoblast fusion; pyruvate metabolic process. 21 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval somatic muscle; wing disc; embryonic myoblast. The phenotypic classes of alleles include: increased mortality; short lived; viable; phenotype; cell death defective; neuroanatomy defective; decreased cell size."
FBgn0031374	Wdr62	-0.32546209	0.380977128	0.999936032	NA	MAPKBP1;WDR62	high;high	NA	NA	NA	"The gene WD repeat domain 62 is referred to in FlyBase by the symbol Dmel\Wdr62 (CG7337, FBgn0031374). It is a protein_coding_gene from Drosophila melanogaster. It has 8 annotated transcripts and 8 polypeptides (7 unique). Gene sequence location is 2L:1884622..1944289. It has the cytological map location 22B4-22B6. Protein features are: Quinoprotein alcohol dehydrogenase-like superfamily; Six-bladed beta-propeller, TolB-like; WD40 repeat; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: RNA binding. It is involved in the biological process described with: mitotic spindle organization; regulation of mitotic cell cycle; RNA splicing. 33 alleles are reported. The phenotypes of these alleles manifest in: neuroblast; mitotic spindle; microtubule organizing center; centrosome; embryonic/larval brain; microtubule. The phenotypic classes of alleles include: partially lethal; decreased cell number; some die during pupal stage; hypoplasia; mitotic cell cycle defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during late pupal stages, in stages of adults of both sexes.  "
FBgn0033095	CG3409	-0.325276167	0.384067941	0.999936032	NA	SLC16A14;SLC16A4;SLC16A9	moderate;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3409 (FBgn0033095). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:6699695..6715892. It has the cytological map location 42C5-42C6. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain. Its molecular function is described by: monocarboxylic acid transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; monocarboxylic acid transport. 17 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; some die during pupal stage; lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during late pupal stages, in adult female stages.  "
FBgn0266525	CG45092	-0.325276167	0.384067941	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG45092 (FBgn0266525). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:6699695..6715892. It has the cytological map location 42C5-42C6. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available.
FBgn0266284	Ns3	-0.325229515	0.355653858	0.999936032	NA	LSG1	high	NA	NA	NA	"The gene Nucleostemin 3 is referred to in FlyBase by the symbol Dmel\Ns3 (CG14788, FBgn0266284). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:1461844..1464220. It has the cytological map location 2B1-2A4. Protein features are: Circularly permuted (CP)-type guanine nucleotide-binding (G) domain; GTP binding domain; GTP-binding protein, orthogonal bundle domain; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: GTPase activity; GTP binding. It is involved in the biological process described with: regulation of insulin receptor signaling pathway; ribosomal subunit export from nucleus; nuclear export; cellular response to starvation; positive regulation of multicellular organism growth. 18 alleles are reported. The phenotypes of these alleles manifest in: salivary gland; sarcomere; eye; Z disc; trichogen cell; mesothoracic tergum; wing; ommatidium; chaeta. The phenotypic classes of alleles include: lethal; developmental rate defective; phenotype; viable; increased mortality during development."
FBgn0038755	Hs6st	-0.325192896	0.437145527	0.999936032	NA	HS6ST1;HS6ST3;HS6ST2	high;moderate;moderate	NA	transmembrane protein	NA	"The gene Heparan sulfate 6-O-sulfotransferase is referred to in FlyBase by the symbol Dmel\Hs6st (CG4451, FBgn0038755). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:19929277..20008512. It has the cytological map location 92B8-92C1. Protein features are: Heparan sulphate 6-sulfotransferase/Protein-tyrosine sulfotransferase; P-loop containing nucleoside triphosphate hydrolase; Sulfotransferase. Its molecular function is described by: heparan sulfate 6-O-sulfotransferase activity. It is involved in the biological process described with: regulation of imaginal disc growth; primary branching, open tracheal system; regulation of decapentaplegic signaling pathway; heparan sulfate proteoglycan biosynthetic process; open tracheal system development; fibroblast growth factor receptor signaling pathway; regulation of canonical Wnt signaling pathway; heparan sulfate proteoglycan biosynthetic process, enzymatic modification; imaginal disc-derived wing margin morphogenesis; chaeta development. 27 alleles are reported. The phenotypes of these alleles manifest in: wing disc; embryonic/larval trachea; wing margin; presumptive embryonic/larval tracheal system; eye; adult posterior midgut epithelium; imaginal tracheoblast; wing margin bristle. The phenotypic classes of alleles include: visible; increased mortality during development; phenotype; increased mortality; partially lethal; decreased occurrence of cell division. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the pupal period.  "
FBgn0035335	mRpL23	-0.325143491	0.380563934	0.999936032	NA	MRPL23;LOC107987373	high;moderate	NA	NA	NA	"The gene mitochondrial ribosomal protein L23 is referred to in FlyBase by the symbol Dmel\mRpL23 (CG1320, FBgn0035335). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 3L:2372844..2373704. It has the cytological map location 62D7. Protein features are: Ribosomal protein L23/L15e core domain; Ribosomal protein L25/L23. Its molecular function is described by: structural constituent of ribosome; RNA binding. It is involved in the biological process described with: translation; mitochondrial translation. 6 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: partially lethal; viable; lethal - all die during P-stage; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 06-12 hour embryonic stages, during early larval stages.  "
FBgn0031043	Naa20A	-0.325136235	0.356199147	0.999936032	NA	NAA20	high	NA	NA	NA	"The gene N(alpha)-acetyltransferase 20 A is referred to in FlyBase by the symbol Dmel\Naa20A (CG14222, FBgn0031043). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is X:19621451..19623074. It has the cytological map location 18D7. Protein features are: Acyl-CoA N-acyltransferase; GNAT domain. Its molecular function is described by: peptide alpha-N-acetyltransferase activity. It is involved in the biological process described with: negative regulation of neuron apoptotic process; histone acetylation; N-terminal peptidyl-methionine acetylation. 4 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; myofibril. The phenotypic classes of alleles include: flightless; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0023531	CG32809	-0.325049563	0.438968594	0.999936032	NA	KIAA1217;SRCIN1	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32809 (FBgn0023531). It is a protein_coding_gene from Drosophila melanogaster. It has 11 annotated transcripts and 11 polypeptides (all unique). Gene sequence location is X:1673110..1692768. It has the cytological map location 2B6-2B7. Protein features are: Actin interacting protein 3, C-terminal; Myc-type, basic helix-loop-helix (bHLH) domain. Its molecular function is described by: protein dimerization activity. It is involved in the biological process described with: . 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; flight defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period.  "
FBgn0030890	CG7536	-0.324979456	0.372336693	0.999936032	NA	XPR1	moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7536 (FBgn0030890). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is X:18078491..18088532. It has the cytological map location 16F6. Protein features are: EXS, C-terminal; SPX domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early pupal stages, in adult female stages.  "
FBgn0036978	Toll-9	-0.324930391	0.431164105	0.999936032	NA	TLR10;TLR2;TLR6;TLR1	high;high;moderate;moderate	NA	transmembrane protein	NA	"The gene Toll-9 is referred to in FlyBase by the symbol Dmel\Toll-9 (CG5528, FBgn0036978). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:20361843..20366724. It has the cytological map location 77B6. Protein features are: Leucine-rich repeat; Leucine-rich repeat domain, L domain-like; Leucine-rich repeat, typical subtype; Toll/interleukin-1 receptor homology (TIR) domain. Its molecular function is unknown. It is involved in the biological process described with: signal transduction. 14 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval hemocyte; eye; leg. The phenotypic classes of alleles include: phenotype; viable; increased mortality during development; developmental rate defective; increased mortality; fertile; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0003942	RpS27A	-0.324916852	0.332810605	0.999936032	NA	RPS27A	high	NA	NA	NA	"The gene Ribosomal protein S27A is referred to in FlyBase by the symbol Dmel\RpS27A (CG5271, FBgn0003942). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:10408352..10410456. It has the cytological map location 31E1. Protein features are: Ribosomal protein S27a; Ubiquitin; Ubiquitin conserved site; Ubiquitin domain; Ubiquitin-related domain; Zinc-binding ribosomal protein. Its molecular function is described by: protein tag; structural constituent of ribosome. It is involved in the biological process described with: protein ubiquitination; cytoplasmic translation; translation. 10 alleles are reported. The phenotypes of these alleles manifest in: macrochaeta; spermatid. The phenotypic classes of alleles include: viable; male sterile; lethal - all die during larval stage; female sterile; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.  "
FBgn0036958	CG17233	-0.324817845	0.418220215	0.999936032	NA	CCDC82	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17233 (FBgn0036958). It is a protein_coding_gene from Drosophila melanogaster. It has 8 annotated transcripts and 8 polypeptides (7 unique). Gene sequence location is 3L:20233173..20241903. It has the cytological map location 77A3. Protein features are: Armadillo-like helical; Domain of unknown function DUF4211; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: . It is involved in the biological process described with: . 7 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during early pupal stages, in adult female stages.  "
FBgn0034588	CG9394	-0.324409375	0.333888019	0.999936032	NA	GPCPD1	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9394 (FBgn0034588). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:21118394..21120705. It has the cytological map location 57C1. Protein features are: Carbohydrate binding module family 20; Carbohydrate-binding-like fold; Glycerophosphocholine phosphodiesterase GPCPD1, CBM20 domain; Glycerophosphodiester phosphodiesterase Gde1; Glycerophosphodiester phosphodiesterase domain; Immunoglobulin-like fold; PLC-like phosphodiesterase, TIM beta/alpha-barrel domain. Its molecular function is described by: starch binding; glycerophosphocholine phosphodiesterase activity; glycerophosphodiester phosphodiesterase activity. It is involved in the biological process described with: glycerophospholipid catabolic process; cellular phosphate ion homeostasis. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages.  "
FBgn0031817	CG9531	-0.324380558	0.397864696	0.999936032	HEMK1	HEMK1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9531 (FBgn0031817). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:6466217..6467698. It has the cytological map location 26D7. Protein features are: DNA methylase, N-6 adenine-specific, conserved site; Methyltransferase small domain; Modification methylase HemK; S-adenosyl-L-methionine-dependent methyltransferase. Its molecular function is described by: protein methyltransferase activity; S-adenosylmethionine-dependent methyltransferase activity; nucleic acid binding. It is involved in the biological process described with: protein methylation. 6 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0036169	Fuca	-0.324128433	0.42912911	0.999936032	NA	FUCA2;FUCA1	high;moderate	NA	NA	NA	NA
FBgn0058198	CG40198	-0.324088601	0.28417552	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG40198 (FBgn0058198). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:4160610..4162235. Its molecular function is described by: . It is involved in the biological process described with: . One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0266446	CG45076	-0.323957964	0.363293548	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG45076 (FBgn0266446). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3R:10768001..10777374. It has the cytological map location 86C6. Its molecular function is described by: . It is involved in the biological process described with: . 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; fertile; viable.
FBgn0051523	CG31523	-0.323935625	0.337078609	0.999936032	NA	ELOVL7;ELOVL1;ELOVL5;ELOVL4;ELOVL2	moderate;moderate;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31523 (FBgn0051523). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (1 unique). Gene sequence location is 3R:4465421..4479207. It has the cytological map location 82B2-82B3. Protein features are: ELO family. Its molecular function is described by: fatty acid elongase activity. It is involved in the biological process described with: fatty acid elongation. 16 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 12-18 embryonic stages, in adult male stages.  "
FBgn0027791	O-fut2	-0.323919297	0.367382495	0.999936032	POFUT2	POFUT2	high	NA	NA	NA	"The gene O-fucosyltransferase 2 is referred to in FlyBase by the symbol Dmel\O-fut2 (CG14789, FBgn0027791). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:1464363..1465996. It has the cytological map location 2A4. Protein features are: GDP-fucose protein O-fucosyltransferase. Its molecular function is described by: peptide-O-fucosyltransferase activity. It is involved in the biological process described with: regulation of transcription, DNA-templated; O-glycan processing; embryo development. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0031048	CG12237	-0.323721711	0.346454515	0.999936032	PHOSPHO2	PHOSPHO2;PHOSPHO1	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12237 (FBgn0031048). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:19641191..19642869. It has the cytological map location 18D11. Protein features are: HAD-like domain; Phosphatase PHOSPHO-type; Pyridoxal phosphate phosphatase-related. Its molecular function is described by: phosphatase activity; pyrophosphatase activity. It is involved in the biological process described with: . 14 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: female semi-sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0051548	CG31548	-0.323720919	0.345987743	0.999936032	NA	HSD17B14;HSD17B8;CBR4	high;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31548 (FBgn0051548). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:5635901..5636852. It has the cytological map location 83B7. Protein features are: NAD(P)-binding domain; Short-chain dehydrogenase/reductase SDR; Short-chain dehydrogenase/reductase, conserved site. Its molecular function is described by: oxidoreductase activity. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0036956	CG13813	-0.32370707	0.392138868	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG13813 (FBgn0036956). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:20231669..20233255. It has the cytological map location 77A3. Protein features are: CHK kinase-like; Protein kinase-like domain; Protein of unknown function DUF227. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages.
FBgn0033507	CG12909	-0.323490527	0.412396736	0.999936032	NA	LYAR	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12909 (FBgn0033507). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:10310113..10311143. It has the cytological map location 47A1. Protein features are: Zinc finger C2H2-type; Zinc finger, C2H2, LYAR-type. Its molecular function is described by: nucleic acid binding. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0050438	CG30438	-0.323361693	0.405152171	0.999936032	NA	UGT8;UGT2B10;UGT2B28;UGT1A3;UGT3A1;UGT3A2;UGT2B4;UGT2B15;UGT2A2;UGT2B17;UGT2B11;UGT2A3;UGT2B7;UGT1A1	high;moderate;low;low;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG30438 (FBgn0050438). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (2 unique). Gene sequence location is 2R:5496674..5549543. It has the cytological map location 41F2-41F3. Protein features are: UDP-glucuronosyl/UDP-glucosyltransferase; UDP-glycosyltransferase family, conserved site. Its molecular function is described by: glucuronosyltransferase activity. It is involved in the biological process described with: metabolic process. 12 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed in adult male stages.  "
FBgn0036550	CG17026	-0.323314681	0.439017868	0.999936032	NA	IMPA2;IMPA1	moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17026 (FBgn0036550). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:15975368..15976428. It has the cytological map location 72C1. Protein features are: Inositol monophosphatase; Inositol monophosphatase, Lithium-sensitive; Inositol monophosphatase, conserved site; Inositol monophosphatase, metal-binding site; Inositol monophosphatase-like. Its molecular function is described by: inositol monophosphate 1-phosphatase activity. It is involved in the biological process described with: dephosphorylation; inositol metabolic process; phosphatidylinositol phosphorylation; signal transduction; inositol phosphate dephosphorylation. 2 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die during P-stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during late larval stages.  "
FBgn0035195	Sac1	-0.323252106	0.352285559	0.999936032	NA	SACM1L	high	NA	transmembrane protein	NA	NA
FBgn0250876	Sema5c	-0.32313938	0.403724642	0.999936032	NA	SEMA5A;SEMA5B;SEMA4C;SEMA7A;SEMA3F;SEMA3E;SEMA4F;SEMA4A;SEMA4D;SEMA4G;SEMA3D;SEMA3C;SEMA3G;SEMA3A;SEMA4B	high;moderate;low;moderate;low;moderate;moderate;low;low;low;moderate;low;moderate;low;moderate	NA	transmembrane protein	NA	NA
FBgn0033879	CG6543	-0.322890694	0.336689523	0.999936032	NA	ECHS1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6543 (FBgn0033879). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:13852947..13854331. It has the cytological map location 50C6. Protein features are: ClpP/crotonase-like domain; Crontonase, C-terminal; Crotonase superfamily; Enoyl-CoA hydratase/isomerase, conserved site. Its molecular function is described by: enoyl-CoA hydratase activity. It is involved in the biological process described with: fatty acid beta-oxidation. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: immune response defective; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the larval period, in adult female stages.  "
FBgn0037930	CG14715	-0.322768624	0.350788381	0.999936032	NA	FKBP2;FKBP9;FKBP7;FKBP14;FKBP10;FKBP11	high;moderate;low;low;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14715 (FBgn0037930). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:11674221..11674923. It has the cytological map location 86E15. Protein features are: FKBP-type peptidyl-prolyl cis-trans isomerase domain; Peptidyl-prolyl cis-trans isomerase, FKBP-type. Its molecular function is described by: FK506 binding; peptidyl-prolyl cis-trans isomerase activity. It is involved in the biological process described with: chaperone-mediated protein folding. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0260462	CG12163	-0.322760641	0.342507633	0.999936032	NA	CTSF;CTSW	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12163 (FBgn0260462). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3R:5237651..5251745. It has the cytological map location 82F6-82F7. Protein features are: Cathepsin propeptide inhibitor domain (I29); Cysteine peptidase, asparagine active site; Cysteine peptidase, cysteine active site; Cysteine peptidase, histidine active site; Peptidase C1A; Peptidase C1A, papain C-terminal. Its molecular function is described by: cysteine-type endopeptidase activity. It is involved in the biological process described with: wing disc development; proteolysis involved in cellular protein catabolic process; salivary gland cell autophagic cell death; chaeta development; autophagic cell death. 18 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, during early pupal stages, in adult male stages.  "
FBgn0003887	betaTub56D	-0.322729334	0.336092275	0.999936032	NA	TUBB4B;TUBB4A;TUBB;TUBB2B;TUBB6;TUBB2A;TUBB3;TUBB8;TUBB1	high;moderate;moderate;moderate;moderate;moderate;low;moderate;low	NA	NA	NA	NA
FBgn0260753	Pdfr	-0.322567304	0.42272556	0.999936032	NA	CALCR;CRHR2;CALCRL;VIPR1;GLP2R;PTH1R;GLP1R;GCGR;SCTR;PTH2R;GHRHR;VIPR2;ADCYAP1R1;GIPR	moderate;low;low;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate	NA	transmembrane protein	GPCR	"The gene Pigment-dispersing factor receptor is referred to in FlyBase by the symbol Dmel\Pdfr (CG13758, FBgn0260753). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is X:2552206..2578640. It has the cytological map location 3A4-3A6. Protein features are: GPCR, family 2, extracellular hormone receptor domain; GPCR, family 2, secretin-like; GPCR, family 2, secretin-like, conserved site; GPCR, family 2-like. Its molecular function is described by: neuropeptide receptor activity; protein binding; calcitonin receptor activity. It is involved in the biological process described with 12 unique terms, many of which group under: rhythmic process; circadian rhythm; homeostatic process; single-multicellular organism process; regulation of circadian rhythm; locomotion; ribose phosphate metabolic process; ion homeostasis; locomotory behavior; behavior. 28 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: gravitaxis defective; locomotor rhythm defective; circadian rhythm defective; circadian behavior defective; viable; temperature response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during early pupal stages.  "
FBgn0003206	Ras64B	-0.322444387	0.367742481	0.999936032	NA	RRAS2;RRAS;KRAS;HRAS;NRAS;RAP1A;RAP1B;MRAS;RALB;RIT2;RIT1;RALA	high;moderate;moderate;moderate;low;low;low;moderate;low;low;low;low	NA	NA	NA	"The gene Ras oncogene at 64B is referred to in FlyBase by the symbol Dmel\Ras64B (CG1167, FBgn0003206). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:4139076..4141398. It has the cytological map location 64A7. Protein features are: P-loop containing nucleoside triphosphate hydrolase; Small GTP-binding protein domain; Small GTPase superfamily; Small GTPase superfamily, Ras type. Its molecular function is described by: GTPase activity; protein binding; GTP binding. It is involved in the biological process described with: Ras protein signal transduction. 29 alleles are reported. The phenotypes of these alleles manifest in: dorsal triple row; humeral sclerite; ventral triple row; embryo; inner photoreceptor cell; embryonic head; photoreceptor cell R7; acellular anatomical structure; embryonic tagma; wing vein. The phenotypic classes of alleles include: phenotype; increased mortality during development; lethal - all die before end of larval stage; size defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 12-24 hour embryonic stages, during late larval stages.  "
FBgn0032727	CG10623	-0.322366902	0.350672086	0.999936032	NA	BHMT2;BHMT;MTR	low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10623 (FBgn0032727). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:18955481..18957311. It has the cytological map location 37B7. Protein features are: Betaine-homocysteine S-methyltransferase, BHMT; Homocysteine-binding domain. Its molecular function is described by: zinc ion binding; betaine-homocysteine S-methyltransferase activity. It is involved in the biological process described with: methionine biosynthetic process. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 06-12 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0259991	CG42488	-0.322189059	0.433803632	0.999936032	NA	TMEM141	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG42488 (FBgn0259991). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:25483098..25485481. It has the cytological map location 96E2. Protein features are: Transmembrane protein 141. Its molecular function is unknown. It is involved in the biological process described with: outer dynein arm assembly; cilium movement. No alleles are reported. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0045759	bin	-0.322116906	0.441196618	0.999936032	NA	FOXF2;FOXF1;FOXH1	high;moderate;moderate	DNA-binding with transcription factor activity(Fork_head)	NA	NA	"The gene biniou is referred to in FlyBase by the symbol Dmel\bin (CG18647, FBgn0045759). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:6990622..6994447. It has the cytological map location 65D6. Protein features are: Fork head domain; Fork head domain conserved site 2; Winged helix-turn-helix DNA-binding domain. Its molecular function is described by: transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; transcription regulatory region sequence-specific DNA binding; sequence-specific DNA binding. It is involved in the biological process described with: salivary gland morphogenesis; regulation of transcription from RNA polymerase II promoter; mesodermal cell fate commitment; positive regulation of transcription from RNA polymerase II promoter. 11 alleles are reported. The phenotypes of these alleles manifest in: circular visceral muscle primordium; embryonic pericardial cell; midgut constriction; longitudinal visceral muscle primordium; visceral mesoderm derivative; presumptive embryonic salivary gland; embryonic somatic muscle; anterior embryonic/larval midgut. The phenotypic classes of alleles include: viable; lethal; cell migration defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed at stages throughout embryogenesis.  "
FBgn0259748	CG42397	-0.322030042	0.33543145	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG42397 (FBgn0259748). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:11973085..11973790. It has the cytological map location 68E4. Protein features are: Chitin binding domain. Its molecular function is described by: chitin binding. It is involved in the biological process described with: chitin metabolic process. No alleles are reported. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed in adults stages of both sexes.
FBgn0025582	eIF3e	-0.322017064	0.342065126	0.999936032	NA	EIF3E	high	NA	NA	NA	"The gene eukaryotic translation initiation factor 3 subunit e is referred to in FlyBase by the symbol Dmel\eIF3e (CG9677, FBgn0025582). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:16785242..16786941. It has the cytological map location 73C4. Protein features are: Eukaryotic translation initiation factor 3 subunit E; Eukaryotic translation initiation factor 3 subunit E, N-terminal; Proteasome component (PCI) domain; Winged helix-turn-helix DNA-binding domain. Its molecular function is described by: translation initiation factor activity. It is involved in the biological process described with: regulation of cell cycle; translational initiation; neuron projection morphogenesis; phagocytosis. 8 alleles are reported. The phenotypes of these alleles manifest in: wing disc; female germline cell; eye disc; embryonic/larval brain. The phenotypic classes of alleles include: lethal; increased mortality; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages.  "
FBgn0034710	CG3292	-0.321819777	0.318157711	0.999936032	ALPPL2	ALPPL2;ALPL;ALPI;ALPP	moderate;moderate;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3292 (FBgn0034710). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:22203694..22205593. It has the cytological map location 58D1. Protein features are: Alkaline phosphatase; Alkaline phosphatase, active site; Alkaline phosphatase-like, alpha/beta/alpha; Alkaline-phosphatase-like, core domain. Its molecular function is described by: alkaline phosphatase activity. It is involved in the biological process described with: dephosphorylation. 6 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed during late larval stages.  "
FBgn0037879	scpr-C	-0.321819777	0.318157711	0.999936032	NA	PI15;R3HDML;CRISPLD2;GLIPR1L1;CLEC18C;CRISPLD1;CLEC18B;CLEC18A	high;high;moderate;moderate;low;low;low;low	NA	NA	NA	"The gene SCP-containing protein C is referred to in FlyBase by the symbol Dmel\scpr-C (CG5106, FBgn0037879). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:11225520..11226681. It has the cytological map location 86D8. Protein features are: CAP domain; Cysteine-rich  secretory protein, allergen V5/Tpx-1-related; Venom allergen 3, insect. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. The phenotype of these alleles manifest in: male accessory gland secondary cell. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed in adult male stages.  "
FBgn0003312	sad	-0.321802465	0.244703038	0.999936032	NA	CYP24A1;CYP27C1;CYP27A1;CYP27B1;CYP11B1;CYP11A1;CYP11B2	moderate;moderate;moderate;low;moderate;moderate;moderate	NA	NA	NA	"The gene shadow is referred to in FlyBase by the symbol Dmel\sad (CG14728, FBgn0003312). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:11877235..11879754. It has the cytological map location 87A1. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I. Its molecular function is described by: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; iron ion binding; ecdysteroid 2-hydroxylase activity; heme binding. It is involved in the biological process described with: dorsal closure; midgut development; ecdysone biosynthetic process; central nervous system development; head involution; motor neuron axon guidance; oxidation-reduction process. 13 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval digestive system; presumptive embryonic/larval nervous system; acellular anatomical structure; membrane-bounded organelle; embryonic/larval foregut; cytoplasm; embryonic head; fused midgut primordium; presumptive embryonic/larval peripheral nervous system; sensory neuron. The phenotypic classes of alleles include: lethal - all die before end of embryonic stage; viable; locomotor behavior defective; some die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0030063	CG1789	-0.321664475	0.397744091	0.999936032	UTP11L	UTP11	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1789 (FBgn0030063). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:8720520..8721503. It has the cytological map location 8A3. Protein features are: Small-subunit processome, Utp11. Its molecular function is described by: . It is involved in the biological process described with: rRNA processing; ribosomal small subunit biogenesis; translation. 4 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; embryonic/larval neuroblast; ganglion mother cell. The phenotypic classes of alleles include: neuroanatomy defective; partially lethal; lethal; lethal - all die during P-stage; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0031356	CG17660	-0.320845239	0.359366192	0.999936032	TMEM87B	TMEM87A;TMEM87B	high;high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17660 (FBgn0031356). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:1707132..1710421. It has the cytological map location 22B1. Protein features are: Lung seven transmembrane receptor-like. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0030806	CG13001	-0.320821248	0.39964931	0.999936032	ZC4H2	ZC4H2	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13001 (FBgn0030806). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:16941086..16942871. It has the cytological map location 15C4. Protein features are: Zinc finger, C4H2-type. Its molecular function is described by: . It is involved in the biological process described with: nervous system development. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die during embryonic stage; lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during early pupal stages.  "
FBgn0024985	CG11448	-0.32079613	0.402269209	0.999936032	RILPL1	RILPL1;RILP;RILPL2	high;moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11448 (FBgn0024985). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is X:1393054..1397337. It has the cytological map location 2A1. Protein features are: JNK/Rab-associated protein-1, N-terminal; RH1 domain; RH2 domain. Its molecular function is described by: small GTPase binding; dynein light intermediate chain binding. It is involved in the biological process described with: cilium assembly; neuron projection morphogenesis. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0030956	CG18259	-0.320547274	0.396755777	0.999936032	NA	POLDIP3	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG18259 (FBgn0030956). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:18781265..18783494. It has the cytological map location 17D5. Protein features are: PDIP3, RNA recognition motif; Polymerase delta-interacting protein 3; RNA recognition motif domain. Its molecular function is described by: RNA binding. It is involved in the biological process described with: mRNA export from nucleus. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0034371	SP2637	-0.320511762	0.404006568	0.999936032	NA	NTAN1	high	NA	NA	NA	"The gene SP2637 is referred to in FlyBase by the symbol Dmel\SP2637 (CG5473, FBgn0034371). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 2R:18640862..18658222. It has the cytological map location 55E3-55E5. Protein features are: Protein N-terminal asparagine amidohydrolase. Its molecular function is described by: protein-N-terminal asparagine amidohydrolase activity. The biological processes in which it is involved are not known. 16 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0025676	CkIIalpha-i3	-0.320443413	0.394327044	0.999936032	NA	NA	NA	NA	NA	NA	"The gene CKII-‘± subunit interactor-3 is referred to in FlyBase by the symbol Dmel\CkII‘±-i3 (CG3217, FBgn0025676). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:708601..710607. It has the cytological map location 61C8. Its molecular function is described by: . It is involved in the biological process described with: . 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0266626	CR45133	-0.320401498	0.355875298	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45133 (FBgn0266626). It is a non_protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts. Gene sequence location is 2R:10152717..10154345. It has the cytological map location 46F3. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0038984	AdipoR	-0.320329167	0.3407023	0.999936032	NA	ADIPOR1;ADIPOR2	high;moderate	NA	transmembrane protein	NA	"The gene Adiponectin receptor is referred to in FlyBase by the symbol Dmel\AdipoR (CG5315, FBgn0038984). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (2 unique). Gene sequence location is 3R:22543693..22547846. It has the cytological map location 94B3. Protein features are: AdipoR/Haemolysin-III-related. Its molecular function is described by: receptor activity; protein-hormone receptor activity; hormone binding. It is involved in the biological process described with: fatty acid oxidation; adiponectin-activated signaling pathway; hormone-mediated signaling pathway; triglyceride homeostasis; positive regulation of insulin secretion; glucose homeostasis; female germ-line stem cell population maintenance. 10 alleles are reported. The phenotype of these alleles manifest in: female germline stem cell. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; some die during pupal stage; viable; lethal; starvation stress response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0033252	CG12769	-0.320274111	0.420807747	0.999936032	NA	IKZF2	high	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG12769 (FBgn0033252). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 2R:8052080..8065554. It has the cytological map location 44A4. Protein features are: Zinc finger C2H2-type. Its molecular function is described by: nucleic acid binding. The biological processes in which it is involved are not known. 13 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: visible; viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages.
FBgn0028562	sut2	-0.320061462	0.353078213	0.999936032	NA	SLC2A7;SLC2A5;SLC2A11;SLC2A9;SLC2A3;SLC2A4;SLC2A2;SLC2A14;SLC2A1	high;moderate;moderate;moderate;low;low;low;low;low	NA	transmembrane protein	NA	"The gene sugar transporter 2 is referred to in FlyBase by the symbol Dmel\sut2 (CG17975, FBgn0028562). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:8087396..8089297. It has the cytological map location 44A4. Protein features are: Major facilitator superfamily domain; Major facilitator,  sugar transporter-like; Sugar/inositol transporter. Its molecular function is described by: substrate-specific transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed within 06-12 and 18-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0033702	CG8854	-0.319659442	0.433363512	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8854 (FBgn0033702). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:12224461..12229310. It has the cytological map location 48E10. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, during late pupal stages.  "
FBgn0062978	CG31808	-0.319430341	0.425543688	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31808 (FBgn0062978). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:16704286..16716195. It has the cytological map location 36A11. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 12-24 hour embryonic stages, during late pupal stages.  "
FBgn0038425	CG14881	-0.319379588	0.420679084	0.999936032	NA	ARMC7;RPP14	high;low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG14881 (FBgn0038425). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:16434899..16436066. It has the cytological map location 89B16. Protein features are: Armadillo-like helical; Armadillo-type fold; HotDog domain; MaoC-like domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0024556	mEFTu1	-0.319032991	0.34564538	0.999936032	NA	TUFM;MIR4721	high;moderate	NA	NA	NA	"The gene mitochondrial translation elongation factor Tu 1 is referred to in FlyBase by the symbol Dmel\mEFTu1 (CG6050, FBgn0024556). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:13507557..13509332. It has the cytological map location 50A14. Protein features are: Elongation factor Tu, domain 2; P-loop containing nucleoside triphosphate hydrolase; Small GTP-binding protein domain; Tr-type G domain, conserved site; Transcription factor, GTP-binding domain; Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal; Translation elongation factor EFTu-like, domain 2; Translation elongation factor EFTu/EF1A, C-terminal; Translation elongation factor EFTu/EF1A, bacterial/organelle; Translation protein, beta-barrel domain. Its molecular function is described by: GTP binding; translation elongation factor activity; GTPase activity. It is involved in the biological process described with: translational elongation; cell proliferation; mitotic cell cycle; Golgi organization. 11 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die during embryonic stage; lethal; short lived; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in adult female stages.  "
FBgn0034072	Dg	-0.31893316	0.433848702	0.999936032	NA	DAG1	high	NA	transmembrane protein	NA	"The gene Dystroglycan is referred to in FlyBase by the symbol Dmel\Dg (CG18250, FBgn0034072). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 2R:16081176..16098564. It has the cytological map location 52E2-52E4. Protein features are: Alpha-dystroglycan domain 2; Cadherin-like; DG-type SEA domain; Dystroglycan; Dystroglycan-type cadherin-like; Immunoglobulin-like fold. Its molecular function is described by: calcium ion binding; structural constituent of muscle; protein binding. It is involved in the biological process described with 19 unique terms, many of which group under: establishment or maintenance of cell polarity; establishment or maintenance of apical/basal cell polarity; nucleotide phosphorylation; establishment or maintenance of polarity of follicular epithelium; single-organism localization; neuron projection development; regulation of production of miRNAs involved in gene silencing by miRNA; regulation of carbohydrate catabolic process; imaginal disc development; axon guidance; cell-cell signaling; cytoskeletal anchoring at plasma membrane; morphogenesis of follicular epithelium; gene silencing. 48 alleles are reported. The phenotypes of these alleles manifest in: wing; actin cytoskeleton; cell component; cell projection; hemocyte; muscle attachment site; membrane-bounded organelle; prepupal integumentary system; embryonic/larval brain; somatic stem cell; embryonic/larval muscle system; contractile fiber part; intracellular membrane-bounded organelle; plasma membrane bounded cell projection; oocyte. The phenotypic classes of alleles include: partially lethal; some die during larval stage; phenotype; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 12-18 embryonic stages, at stages throughout the pupal period.  "
FBgn0032298	CG6724	-0.318730866	0.378712913	0.999936032	WDR12	WDR12	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6724 (FBgn0032298). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:10768234..10769952. It has the cytological map location 32A5. Protein features are: G-protein beta WD-40 repeat; NLE; WD repeat WDR12/Ytm1; WD40 repeat; WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. It is involved in the biological process described with: maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); maturation of 5.8S rRNA; maturation of LSU-rRNA. 11 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; embryonic/larval neuroblast; ganglion mother cell; trichogen cell. The phenotypic classes of alleles include: fertile; stress response defective; increased mortality; some die during P-stage; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, during early larval stages.  "
FBgn0004103	Pp1-87B	-0.318489443	0.346443342	0.999936032	NA	PPP1CC;PPP1CA;PPP1CB	high;high;low	NA	NA	NA	"The gene Protein phosphatase 1 at 87B is referred to in FlyBase by the symbol Dmel\Pp1-87B (CG5650, FBgn0004103). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:12423621..12425917. It has the cytological map location 87B9-87B10. Protein features are: Calcineurin-like phosphoesterase domain, ApaH type; Metallo-dependent phosphatase-like; Serine-threonine protein phosphatase, N-terminal; Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase. Its molecular function is described by: protein serine/threonine phosphatase activity; myosin phosphatase activity. It is involved in the biological process described with 19 unique terms, many of which group under: visual behavior; adult locomotory behavior; single-organism localization; positive regulation of Ras protein signal transduction; cellular component morphogenesis; microtubule-based process; response to light stimulus; locomotory behavior; spindle organization; endocytosis; regulation of ERK1 and ERK2 cascade; multi-organism reproductive process. 22 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval optic lobe; neuroblast; ganglion mother cell; eye disc; imaginal disc; nuclear chromosome; eye; eye photoreceptor cell. The phenotypic classes of alleles include: increased mortality; phenotype; visible; partially lethal - majority die; sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0033264	Nup50	-0.318480902	0.389977792	0.999936032	NA	NUP50	high	NA	transmembrane protein	NA	"The gene Nucleoporin 50kD is referred to in FlyBase by the symbol Dmel\Nup50 (CG2158, FBgn0033264). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:8123036..8125058. It has the cytological map location 44B2-44B3. Protein features are: Nuclear pore complex, NUP2/50/61; PH domain-like; Ran binding domain. Its molecular function is described by: Ran GTPase binding; chromatin DNA binding; protein binding. It is involved in the biological process described with: heat shock-mediated polytene chromosome puffing; phagocytosis; positive regulation of transcription from RNA polymerase II promoter; SMAD protein import into nucleus. 5 alleles are reported. The phenotypes of these alleles manifest in: tormogen cell; trichogen cell; embryonic/larval neuroblast. The phenotypic classes of alleles include: long lived; pain response defective; neuroanatomy defective; visible; viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0013763	Idgf6	-0.31826435	0.382605314	0.999936032	NA	CHIT1	moderate	NA	NA	NA	"The gene Imaginal disc growth factor 6 is referred to in FlyBase by the symbol Dmel\Idgf6 (CG5210, FBgn0013763). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:16691022..16693751. It has the cytological map location 53D2. Protein features are: Chitinase II; Chitinase insertion domain; Glycoside hydrolase family 18, catalytic domain; Glycoside hydrolase superfamily; Imaginal disc growth factor. Its molecular function is described by: chitin binding; imaginal disc growth factor receptor binding; chitinase activity. It is involved in the biological process described with: carbohydrate metabolic process; chitin-based cuticle development; ecdysis, chitin-based cuticle; imaginal disc development; chitin catabolic process; cuticle chitin catabolic process; wound healing. 3 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval cuticle. The phenotypic classes of alleles include: wound healing defective; majority die during larval stage; some die during pupal stage; partially lethal - majority die; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0034168	CG15614	-0.3179996	0.39218728	0.999936032	NA	NA	NA	NA	transmembrane protein	GPCR	"This gene is referred to in FlyBase by the symbol Dmel\CG15614 (FBgn0034168). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:16945555..16947231. It has the cytological map location 53E2. Protein features are: G protein-coupled receptor, rhodopsin-like; GPCR, rhodopsin-like, 7TM. Its molecular function is described by: G-protein coupled receptor activity. It is involved in the biological process described with: G-protein coupled receptor signaling pathway. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 06-18 hour embryonic stages.  "
FBgn0028506	CG4455	-0.317641851	0.447097748	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG4455 (FBgn0028506). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:16352934..16354539. It has the cytological map location 35F12. Its molecular function is unknown. The biological processes in which it is involved are not known. 12 alleles are reported. The phenotypes of these alleles manifest in: macrochaeta; eye. The phenotypic classes of alleles include: visible; viable; fertile; female fertile; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.
FBgn0002638	Rcc1	-0.317066111	0.382959217	0.999936032	NA	RCC1	high	NA	NA	NA	"The gene Regulator of chromosome condensation 1 is referred to in FlyBase by the symbol Dmel\Rcc1 (CG10480, FBgn0002638). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3L:5930262..5932773. It has the cytological map location 65A1. Protein features are: Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; Regulator of chromosome condensation, RCC1. Its molecular function is described by: chromatin binding; Ran guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: central nervous system development; regulation of mitotic cell cycle; ventral cord development; regulation of nucleocytoplasmic transport; NLS-bearing protein import into nucleus; regulation of neurogenesis. 24 alleles are reported. The phenotypes of these alleles manifest in: neurosecretory neuron; female organism; ganglion mother cell; somatic precursor cell; somatic stem cell; sensory organ cell; multi-cell-component structure; ovariole; integumentary system; gamete. The phenotypic classes of alleles include: some die during P-stage; increased mortality; phenotype; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0052483	CG32483	-0.31696082	0.356878805	0.999936032	SCPEP1	SCPEP1	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32483 (FBgn0052483). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:688523..690081. It has the cytological map location 61C8. Protein features are: Alpha/Beta hydrolase fold; Peptidase S10, serine carboxypeptidase. Its molecular function is described by: serine-type carboxypeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during early larval stages.  "
FBgn0040843	CG15213	-0.316774693	0.444883184	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15213 (FBgn0040843). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:5132796..5133220. It has the cytological map location 64C7. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during early pupal stages.  "
FBgn0259482	Mob3	-0.316768277	0.417006425	0.999936032	NA	MOB3B;MOB3A;MOB3C;MOB1B;MOB1A	high;high;moderate;low;low	NA	NA	NA	"The gene MOB kinase activator 3 is referred to in FlyBase by the symbol Dmel\Mob3 (CG4946, FBgn0259482). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:10265336..10266570. It has the cytological map location 31B1. Protein features are: MOB kinase activator family. Its molecular function is described by: protein kinase binding. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: pain response defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0262123	l(2)41Ab	-0.316689165	0.344442255	0.999936032	NA	CCDC40	high	NA	NA	NA	"The gene lethal (2) 41Ab is referred to in FlyBase by the symbol Dmel\l(2)41Ab (CG41265, FBgn0262123). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:1349392..1443935. It has the cytological map location h41. Its molecular function is described by: . It is involved in the biological process described with: axonemal dynein complex assembly; epithelial cilium movement involved in determination of left/right asymmetry; axoneme assembly; cilium movement. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: lethal."
FBgn0260770	CG42568	-0.31618718	0.449017437	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG42568 (FBgn0260770). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:24157668..24159312. It has the cytological map location 60C1. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed during early larval stages, during late pupal stages, in adult male stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0034419	CG15111	-0.315882576	0.365097724	0.999936032	ABHD12	ABHD12;ABHD12B	high;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15111 (FBgn0034419). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:19137372..19141034. It has the cytological map location 56B5. Protein features are: Alpha/Beta hydrolase fold; Serine aminopeptidase, S33. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: flight defective; viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed in adult male stages.  "
FBgn0021856	l(2)k14505	-0.315797868	0.372195534	0.999936032	NA	ATPAF2	high	NA	NA	NA	"The gene lethal (2) k14505 is referred to in FlyBase by the symbol Dmel\l(2)k14505 (CG8674, FBgn0021856). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:21261168..21262411. It has the cytological map location 39C1. Protein features are: ATP12, ATP synthase F1-assembly protein; Orthogonal Bundle domain in ATP12. Its molecular function is unknown. It is involved in the biological process described with: proton-transporting ATP synthase complex assembly. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0005671	Vha55	-0.315547614	0.344793808	0.999936032	NA	ATP6V1B2;ATP6V1B1	high;moderate	NA	NA	NA	"The gene Vacuolar H<sup>+</sup>-ATPase 55kD subunit is referred to in FlyBase by the symbol Dmel\Vha55 (CG17369, FBgn0005671). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:12623762..12627829. It has the cytological map location 87C2-87C3. Protein features are: ATPase, F1/V1 complex, beta/alpha subunit, C-terminal; ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain; ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain; ATPase, V1 complex, subunit B; ATPase, alpha/beta subunit, nucleotide-binding domain, active site; P-loop containing nucleoside triphosphate hydrolase; V-type ATP synthase regulatory subunit B/beta. Its molecular function is described by: proton-transporting ATPase activity, rotational mechanism; ATP binding. It is involved in the biological process described with: vacuolar acidification; ATP hydrolysis coupled proton transport; ATP metabolic process. 28 alleles are reported. The phenotypes of these alleles manifest in: Malpighian tubule; multivesicular body; eye disc; adult Malpighian tubule. The phenotypic classes of alleles include: partially lethal - majority die; cell number defective; viable; phenotype; lethal - all die before end of embryonic stage; lethal - all die before end of first instar larval stage; increased mortality; short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0031483	CG9641	-0.315439547	0.452816077	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9641 (FBgn0031483). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:2974859..2976862. It has the cytological map location 23C4. Protein features are: Domain of unknown function DUF4780. Its molecular function is unknown. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0030872	Ucp4A	-0.315179819	0.363470172	0.999936032	SLC25A27	SLC25A27;SLC25A14;UCP2;UCP1;SLC25A30;UCP3	high;low;moderate;moderate;low;moderate	NA	NA	NA	"The gene Ucp4A is referred to in FlyBase by the symbol Dmel\Ucp4A (CG6492, FBgn0030872). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:17844949..17848223. It has the cytological map location 16E1. Protein features are: Mitochondrial carrier UCP-like; Mitochondrial carrier domain; Mitochondrial substrate/solute carrier. Its molecular function is described by: oxidative phosphorylation uncoupler activity; transmembrane transporter activity. It is involved in the biological process described with: proton transport; regulation of mitochondrial membrane potential; mitochondrial transport; response to oxidative stress; response to cold. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: long lived; increased mortality; fertile; short lived; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0031857	LUBEL	-0.315086469	0.431709161	0.999936032	NA	RNF31	high	NA	NA	NA	"The gene Linear Ubiquitin E3 ligase is referred to in FlyBase by the symbol Dmel\LUBEL (CG11321, FBgn0031857). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (7 unique). Gene sequence location is 2L:6759829..6772755. It has the cytological map location 27B1. Protein features are: E3 ubiquitin-protein ligase RNF31; E3 ubiquitin-protein ligase RNF31, UBA-like domain; IBR domain; Zinc finger, RING-type; Zinc finger, RING/FYVE/PHD-type; Zinc finger, RanBP2-type. Its molecular function is described by: zinc ion binding; K48-linked polyubiquitin binding; ubiquitin protein ligase activity; ubiquitin-protein transferase activity; K63-linked polyubiquitin binding; linear polyubiquitin binding. It is involved in the biological process described with: protein polyubiquitination; heat acclimation; protein linear polyubiquitination. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: flight defective; viable; short lived; heat stress response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0051097	CG31097	-0.315086469	0.431709161	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG31097 (FBgn0051097). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:25296128..25297778. It has the cytological map location 96D1. Protein features are: CHK kinase-like; Protein kinase-like domain; Protein of unknown function DUF227. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; embryonic/larval neuroblast. The phenotypic classes of alleles include: viable; lethal; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages.
FBgn0030817	CG4991	-0.314894824	0.408281587	0.999936032	NA	SLC36A2;SLC36A1;SLC36A3;SLC36A4	moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4991 (FBgn0030817). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (2 unique). Gene sequence location is X:17091854..17104562. It has the cytological map location 15E2-15E3. Protein features are: Amino acid transporter, transmembrane domain. Its molecular function is described by: amino acid transmembrane transporter activity. It is involved in the biological process described with: amino acid transmembrane transport. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0037185	CG11367	-0.31484618	0.451430377	0.999936032	NA	TMEM64	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11367 (FBgn0037185). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:22728111..22733446. It has the cytological map location 80A1. Protein features are: SNARE associated Golgi protein; Transmembrane protein TMEM64. Its molecular function is described by: . It is involved in the biological process described with: . 15 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period.  "
FBgn0051898	CG31898	-0.314835279	0.442282092	0.999936032	NA	FAM104A	low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG31898 (FBgn0051898). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:8400421..8401592. It has the cytological map location 29C1. Its molecular function is described by: . It is involved in the biological process described with: . 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0266258	CR44953	-0.314835279	0.442282092	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44953 (FBgn0266258). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3R:29755190..29759040. It has the cytological map location 99B10. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0053494	CG33494	-0.314706011	0.445846772	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG33494 (FBgn0053494). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:25493481..25495161. It has the cytological map location 96E2. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during early pupal stages.
FBgn0030878	CG6769	-0.314550467	0.367831412	0.999936032	ZNF622	ZNF622	high	DNA-binding with transcription factor activity	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6769 (FBgn0030878). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:17861002..17862775. It has the cytological map location 16E2. Protein features are: Matrin/U1-C-like, C2H2-type zinc finger; Zinc finger C2H2-type; Zinc finger, double-stranded RNA binding. Its molecular function is described by: zinc ion binding; nucleic acid binding. It is involved in the biological process described with: ribosomal large subunit biogenesis. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: male semi-sterile; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 06-12 and 18-24 hour embryonic stages, during early larval stages.  "
FBgn0032587	CG5953	-0.314438689	0.417091457	0.999936032	NA	NA	NA	DNA-binding with transcription factor activity(MADF)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5953 (FBgn0032587). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 2L:16508078..16532877. It has the cytological map location 36A2-36A3. Protein features are: MADF domain; WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. It is involved in the biological process described with: lateral inhibition. 30 alleles are reported. The phenotypes of these alleles manifest in: chaeta; mesothoracic tergum. The phenotypic classes of alleles include: lethal; fertile; visible; viable; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages, during late pupal stages.  "
FBgn0028670	Vha100-2	-0.314255566	0.348796255	0.999936032	NA	ATP6V0A4;ATP6V0A1;ATP6V0A2;TCIRG1	high;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene Vacuolar H<sup>+</sup> ATPase 100kD subunit 2 is referred to in FlyBase by the symbol Dmel\Vha100-2 (CG18617, FBgn0028670). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:18390323..18399169. It has the cytological map location 91A5. Protein features are: ATPase, V0 complex, subunit 116kDa, eukaryotic; V-type  ATPase, V0 complex, 116kDa subunit family. Its molecular function is described by: ATPase binding; proton-transporting ATPase activity, rotational mechanism. It is involved in the biological process described with: ATP synthesis coupled proton transport; ATP hydrolysis coupled proton transport; vacuolar acidification; vacuolar proton-transporting V-type ATPase complex assembly. 21 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval midgut; chaeta. The phenotypic classes of alleles include: lethal; short lived; fertile; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult female stages.  "
FBgn0051015	PH4alphaPV	-0.313866147	0.403661565	0.999936032	NA	P4HA1;P4HA3;P4HA2	moderate;moderate;low	NA	NA	NA	"The gene prolyl-4-hydroxylase-alpha PV is referred to in FlyBase by the symbol Dmel\PH4‘±PV (CG31015, FBgn0051015). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:30646106..30648551. It has the cytological map location 100A1. Protein features are: Oxoglutarate/iron-dependent dioxygenase; Prolyl 4-hydroxylase alpha-subunit, N-terminal; Prolyl 4-hydroxylase, alpha subunit; Tetratricopeptide-like helical domain. Its molecular function is described by: L-ascorbic acid binding; procollagen-proline 4-dioxygenase activity; iron ion binding; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. It is involved in the biological process described with: oxidation-reduction process. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, in adult female stages.  "
FBgn0015393	hoip	-0.313695376	0.36603815	0.999936032	NA	SNU13	high	NA	NA	NA	"The gene hoi-polloi is referred to in FlyBase by the symbol Dmel\hoip (CG3949, FBgn0015393). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:9699791..9700459. It has the cytological map location 30C5. Protein features are: 50S ribosomal protein L30e-like; H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote; Ribosomal protein L7Ae conserved site; Ribosomal protein L7Ae/L30e/S12e/Gadd45; Ribosomal protein L7Ae/L8/Nhp2 family. Its molecular function is described by: mRNA binding; RNA binding. It is involved in the biological process described with: posttranscriptional regulation of gene expression; positive regulation of translation; nervous system development; peripheral nervous system development; mRNA splicing, via spliceosome; muscle tissue morphogenesis; maturation of SSU-rRNA; maturation of LSU-rRNA. 14 alleles are reported. The phenotypes of these alleles manifest in: intracellular part; abdomen; myotube; oblique muscle; multi-cell-component structure; ISN innervated muscle of A1-7; organ system; intracellular non-membrane-bounded organelle; lateral oblique muscle 1; presumptive embryonic/larval nervous system; tagma; contractile fiber part. The phenotypic classes of alleles include: phenotype; viable; increased mortality during development; lethal - all die before end of first instar larval stage; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0039854	CG1635	-0.313485442	0.376610235	0.999936032	ACOT9	ACOT9	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1635 (FBgn0039854). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:31588673..31590392. It has the cytological map location 100C7. Protein features are: HotDog domain; Hotdog acyl-CoA thioesterase (ACOT)-type domain. Its molecular function is described by: acyl-CoA hydrolase activity. It is involved in the biological process described with: acyl-CoA metabolic process. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult female stages.  "
FBgn0025827	CG6421	-0.313458679	0.272674142	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG6421 (FBgn0025827). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:16872250..16872906. It has the cytological map location 53D15. Protein features are: Invertebrate-type lysozyme; Lysozyme-like domain. Its molecular function is described by: lysozyme activity. It is involved in the biological process described with: defense response to Gram-negative bacterium. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed in adults stages of both sexes.
FBgn0031681	pgant5	-0.313383771	0.397869419	0.999936032	NA	GALNT1;GALNT13;POC1B-GALNT4;GALNTL5;GALNT6;GALNT12;GALNT5;GALNT11;GALNT7;GALNT3;GALNTL6;GALNT4;GALNT10	high;moderate;low;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene polypeptide GalNAc transferase 5 is referred to in FlyBase by the symbol Dmel\pgant5 (CG31651, FBgn0031681). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:5072170..5093592. It has the cytological map location 25C4-25C6. Protein features are: Glycosyltransferase 2-like; Nucleotide-diphospho-sugar transferases; Ricin B, lectin domain. Its molecular function is described by: polypeptide N-acetylgalactosaminyltransferase activity. It is involved in the biological process described with: oligosaccharide biosynthetic process. 17 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval copper cell; embryonic/larval gut. The phenotypic classes of alleles include: lethal; viable; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed during late pupal stages.  "
FBgn0001170	H2.0	-0.313380974	0.453382598	0.999936032	NA	HLX	high	DNA-binding with transcription factor activity(Homeobox)	NA	NA	"The gene Homeodomain protein 2.0 is referred to in FlyBase by the symbol Dmel\H2.0 (CG11607, FBgn0001170). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:6013059..6019402. It has the cytological map location 26B2-26B3. Protein features are: Homeobox domain; Homeobox domain, metazoa; Homeobox domain-like; Homeobox, conserved site. Its molecular function is described by: sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated. 5 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: visible; lethal - all die during larval stage; lethal - all die before end of pupal stage; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 06-24 hour embryonic stages.  "
FBgn0010825	Gug	-0.312995869	0.398653701	0.999936032	NA	RERE;ATN1	high;moderate	DNA-binding with transcription factor activity(Myb_DNA-binding)	NA	NA	"The gene Grunge is referred to in FlyBase by the symbol Dmel\Gug (CG6964, FBgn0010825). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (8 unique). Gene sequence location is 3L:8449922..8472669. It has the cytological map location 66C13-66D1. Protein features are: Atrophin-like; ELM2 domain; Homeobox domain-like; SANT domain; SANT/Myb domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: transcription corepressor activity; DNA binding; histone deacetylase activity; repressing transcription factor binding. It is involved in the biological process described with 12 unique terms, many of which group under: signal transduction; cell communication; response to stimulus; behavior; larval somatic muscle development; negative regulation of nucleic acid-templated transcription; regulation of histone acetylation; pattern specification process; transmembrane receptor protein tyrosine kinase signaling pathway; multi-organism process; organelle organization; embryonic pattern specification; organic cyclic compound biosynthetic process. 48 alleles are reported. The phenotypes of these alleles manifest in: membrane-bounded organelle; cytoplasm; plasma membrane bounded cell projection; sensory system neuron; larval abdominal segment 4; wing vein; larval abdominal segment 2; epidermis; embryonic segment; embryonic/first instar larval cuticle. The phenotypic classes of alleles include: increased mortality; lethal - all die before end of larval stage; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0031804	CG9500	-0.312956727	0.304877688	0.999936032	FIBCD1	FIBCD1;ANGPTL3;ANGPT4;FGA;ANGPT1;ANGPT2;FGL2;FCN3;FCN2;MFAP4;FCN1;TNR;ANGPTL5;ANGPTL1;TNXB;FGG;TNC;ANGPTL4;ANGPTL2;FGB;TNN;ANGPTL6;ANGPTL7;FGL1	moderate;moderate;moderate;moderate;low;moderate;moderate;low;low;moderate;low;low;low;moderate;low;low;low;low;low;low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9500 (FBgn0031804). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:6357005..6358318. It has the cytological map location 26C3. Protein features are: Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain; Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1; Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult male stages.  "
FBgn0001084	fy	-0.312885976	0.447178035	0.999936032	FUZ	FUZ	high	NA	NA	NA	"The gene fuzzy is referred to in FlyBase by the symbol Dmel\fy (CG13396, FBgn0001084). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:8401476..8403280. It has the cytological map location 29C1. Protein features are: Fuzzy protein. Its molecular function is unknown. It is involved in the biological process described with: establishment of imaginal disc-derived wing hair orientation; establishment of planar polarity; establishment or maintenance of cell polarity. 21 alleles are reported. The phenotypes of these alleles manifest in: macrochaeta; wing margin bristle; trichome; wing cell; bract; abdominal sternite bristle; wing hair; trichogen cell. The phenotypic classes of alleles include: viable; visible; planar polarity defective; wild-type. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0051278	CG31278	-0.31251938	0.42003114	0.999936032	NA	PDF	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31278 (FBgn0051278). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:10707398..10708340. It has the cytological map location 86C4. Protein features are: Peptide deformylase. Its molecular function is described by: peptide deformylase activity. It is involved in the biological process described with: N-terminal protein amino acid modification; co-translational protein modification; peptidyl-methionine modification. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.  "
FBgn0031782	WDR79	-0.312495317	0.406495945	0.999936032	WRAP53	WRAP53	high	NA	NA	NA	"The gene WD repeat domain 79 is referred to in FlyBase by the symbol Dmel\WDR79 (CG9226, FBgn0031782). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:6125879..6127775. It has the cytological map location 26B7. Protein features are: WD40 repeat; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: box C/D snoRNA binding. It is involved in the biological process described with: Cajal body organization. 9 alleles are reported. The phenotype of these alleles manifest in: Cajal body. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0031435	Elba2	-0.312482639	0.446581969	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Early boundary activity 2 is referred to in FlyBase by the symbol Dmel\Elba2 (CG9883, FBgn0031435). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:2577687..2579179. It has the cytological map location 23A1. Protein features are: BEN domain. Its molecular function is described by: sequence-specific DNA binding; chromatin binding; chromatin insulator sequence binding. It is involved in the biological process described with: chromatin silencing; negative regulation of transcription, DNA-templated; chromatin organization. 11 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: short lived; viable; locomotor behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0034606	ASPP	-0.312317401	0.455465043	0.999936032	NA	PPP1R13B;TP53BP2;PPP1R13L	high;moderate;moderate	NA	NA	NA	"The gene Ankyrin-repeat, SH3-domain, and Proline-rich-region containing Protein is referred to in FlyBase by the symbol Dmel\ASPP (CG18375, FBgn0034606). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 2R:21217856..21251150. It has the cytological map location 57D2-57D4. Protein features are: Ankyrin repeat; Ankyrin repeat-containing domain; SH3 domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: protein tyrosine kinase activator activity. It is involved in the biological process described with: positive regulation of protein tyrosine kinase activity. 20 alleles are reported. The phenotypes of these alleles manifest in: wing; ommatidium; eye; interommatidial bristle. The phenotypic classes of alleles include: partially lethal; phenotype; increased mortality during development; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the pupal period.  "
FBgn0030270	CG15199	-0.312142145	0.283259535	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG15199 (FBgn0030270). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:11140474..11141835. It has the cytological map location 10A7-10A8. Protein features are: Single domain Von Willebrand factor type C domain. Its molecular function is unknown. It is involved in the biological process described with: defense response to virus. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages.
FBgn0004797	mdy	-0.312097055	0.428356475	0.999936032	NA	DGAT1;MIR6848;SOAT1;SOAT2	high;moderate;low;low	NA	transmembrane protein	NA	"The gene midway is referred to in FlyBase by the symbol Dmel\mdy (CG31991, FBgn0004797). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2L:16816660..16826964. It has the cytological map location 36B1-36B2. Protein features are: Diacylglycerol O-acyltransferase 1; Membrane bound O-acyl transferase, MBOAT; Sterol O-acyltransferase, ACAT/DAG/ARE types. Its molecular function is described by: diacylglycerol O-acyltransferase activity. It is involved in the biological process described with: regulation of nurse cell apoptotic process; oogenesis; negative regulation of lipid storage; wing disc development; triglyceride biosynthetic process. 15 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval oenocyte; salivary gland; lipid particle; egg chamber. The phenotypic classes of alleles include: starvation stress response defective; female sterile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 06-18 hour embryonic stages.  "
FBgn0034968	RpL12	-0.312007876	0.353149547	0.999936032	NA	RPL12	high	NA	NA	NA	"The gene Ribosomal protein L12 is referred to in FlyBase by the symbol Dmel\RpL12 (CG3195, FBgn0034968). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:24060378..24061860. It has the cytological map location 60B7. Protein features are: Ribosomal protein L11, C-terminal; Ribosomal protein L11, N-terminal; Ribosomal protein L11, conserved site; Ribosomal protein L11/L12. Its molecular function is described by: structural constituent of ribosome; rRNA binding. It is involved in the biological process described with: cytoplasmic translation; ribosomal large subunit assembly; translation. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; developmental rate defective; viable; lethal - all die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0039804	CG15544	-0.311902705	0.391415123	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG15544 (FBgn0039804). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:30827819..30842034. It has the cytological map location 100A6. Its molecular function is unknown. The biological processes in which it is involved are not known. 8 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during early pupal stages.
FBgn0000056	Adhr	-0.31180006	0.451821561	0.999936032	NA	HPGD	moderate	NA	NA	NA	"The gene Adh-related is referred to in FlyBase by the symbol Dmel\Adhr (CG3484, FBgn0000056). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:14615552..14618902. It has the cytological map location 35B3. Protein features are: Alcohol dehydrogenase, insect-type; Alcohol dehydrogenase-related; NAD(P)-binding domain; Short-chain dehydrogenase/reductase SDR; Short-chain dehydrogenase/reductase, conserved site. Its molecular function is described by: alcohol dehydrogenase (NAD) activity. It is involved in the biological process described with: oxidation-reduction process. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of low expression.  Peak expression observed at stages throughout the larval period, in stages of adults of both sexes.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0266579	tau	-0.311776525	0.451051702	0.999936032	NA	MAPT;MAP2;MAP4	high;moderate;moderate	NA	NA	NA	"The gene tau is referred to in FlyBase by the symbol Dmel\tau (CG45110, FBgn0266579). It is a protein_coding_gene from Drosophila melanogaster. It has 13 annotated transcripts and 13 polypeptides (11 unique). Gene sequence location is 3R:27639886..27656996. It has the cytological map location 98A14-98A13. Protein features are: Microtubule associated protein,  tubulin-binding repeat; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: microtubule binding. It is involved in the biological process described with: lateral inhibition; microtubule-based process; rhabdomere morphogenesis; microtubule cytoskeleton organization; negative regulation of neuron death. 31 alleles are reported. The phenotypes of these alleles manifest in: plasma membrane bounded cell projection; cell projection; cell component; larval tagma; cell cluster organ; adult head segment; photoreceptor cell; wing disc; neuron; compound sense organ; supramolecular complex; oocyte nucleus; external sensillum; cell. The phenotypic classes of alleles include: phenotype; increased mortality during development; increased mortality; behavior defective."
FBgn0034921	DCP1	-0.311635361	0.411958182	0.999936032	NA	DCP1A;DCP1B	high;high	NA	NA	NA	"The gene Decapping protein 1 is referred to in FlyBase by the symbol Dmel\DCP1 (CG11183, FBgn0034921). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:23888764..23890276. It has the cytological map location 60A8. Protein features are: PH domain-like; mRNA-decapping enzyme subunit 1; mRNA-decapping enzyme, C-terminal. Its molecular function is described by: enzyme activator activity; protein binding; enzyme regulator activity; mRNA binding. It is involved in the biological process described with: regulation of cytoplasmic mRNA processing body assembly; deadenylation-independent decapping of nuclear-transcribed mRNA; gene silencing by miRNA; nuclear-transcribed mRNA catabolic process; pole plasm oskar mRNA localization; positive regulation of catalytic activity; positive regulation of gene silencing by miRNA; deadenylation-dependent decapping of nuclear-transcribed mRNA. 19 alleles are reported. The phenotypes of these alleles manifest in: embryonic abdominal segment; pole cell; egg chamber; P-body; embryo. The phenotypic classes of alleles include: phenotype; increased mortality during development; increased mortality; lethal - all die before end of larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.  "
FBgn0033209	CG12107	-0.311552678	0.374638404	0.999936032	C20orf24	C20orf24;TGIF2-C20orf24	high;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12107 (FBgn0033209). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:7674450..7675362. It has the cytological map location 43E9. Protein features are: Rab5-interacting protein; Rab5-interacting protein family. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0030855	CG5800	-0.311339632	0.429298854	0.999936032	DDX10	DDX10;DDX18	high;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5800 (FBgn0030855). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:17636281..17639003. It has the cytological map location 16B10. Protein features are: ATP-dependent RNA helicase DEAD-box, conserved site; DEAD/DEAH box helicase domain; Domain of unknown function DUF4217; Helicase superfamily 1/2, ATP-binding domain; Helicase, C-terminal; P-loop containing nucleoside triphosphate hydrolase; RNA helicase, DEAD-box type, Q motif. Its molecular function is described by: ATP binding; ATP-dependent RNA helicase activity; RNA helicase activity; nucleic acid binding. It is involved in the biological process described with: RNA secondary structure unwinding; larval somatic muscle development. 4 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; embryonic/larval neuroblast; Z disc; embryonic/larval somatic muscle; sarcomere. The phenotypic classes of alleles include: phenotype; increased mortality during development; lethal; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0003961	Uro	-0.311169103	0.320298038	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Urate oxidase is referred to in FlyBase by the symbol Dmel\Uro (CG7171, FBgn0003961). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:7780085..7781415. It has the cytological map location 28C3. Protein features are: Uricase; Uricase, conserved site. Its molecular function is described by: urate oxidase activity. It is involved in the biological process described with: oxidation-reduction process; allantoin biosynthetic process; purine nucleobase metabolic process; response to ethanol. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile; chemical resistant; chemical sensitive; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed during early larval stages.  "
FBgn0021795	Tapdelta	-0.31075398	0.355267573	0.999936032	NA	SSR4	high	NA	transmembrane protein	NA	"The gene Translocon-associated protein ‘Ç is referred to in FlyBase by the symbol Dmel\Tap‘Ç (CG9035, FBgn0021795). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:11370300..11371335. It has the cytological map location 47F7. Protein features are: Translocon-associated. Its molecular function is described by: signal sequence binding. It is involved in the biological process described with: protein retention in ER lumen. 10 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval salivary gland. The phenotypic classes of alleles include: viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0036834	CG6836	-0.310533834	0.452654579	0.999936032	NA	SLC51A;TMEM184B	high;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6836 (FBgn0036834). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:18950629..18955406. It has the cytological map location 75F1. Protein features are: Organic solute transporter subunit alpha/Transmembrane protein 184. Its molecular function is described by: transporter activity. It is involved in the biological process described with: transport. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-18 embryonic stages, during late pupal stages.  "
FBgn0032170	CG4658	-0.310484142	0.36917793	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4658 (FBgn0032170). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (2 unique). Gene sequence location is 2L:9957132..9960168. It has the cytological map location 30F2. Protein features are: TLDc domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages, in stages of adults of both sexes.  "
FBgn0034796	CG3700	-0.310329416	0.458590417	0.999936032	NA	NA	NA	Maybe TF	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3700 (FBgn0034796). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:22894435..22895745. It has the cytological map location 59B4. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 5 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, during early pupal stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0051265	CG31265	-0.310253655	0.36181984	0.999936032	NA	PRSS37	low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31265 (FBgn0051265). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:17128212..17129120. It has the cytological map location 89F1. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0035519	CG1309	-0.310240172	0.369364384	0.999936032	ABHD16A	ABHD16A;ABHD16B	high;moderate	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG1309 (FBgn0035519). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:4259430..4261643. It has the cytological map location 64A12. Protein features are: Alpha/Beta hydrolase fold; Alpha/beta hydrolase fold-1. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed in adult male stages.
FBgn0086368	tw	-0.310105916	0.446998633	0.999936032	NA	POMT2;POMT1	high;low	NA	transmembrane protein	NA	"The gene twisted is referred to in FlyBase by the symbol Dmel\tw (CG12311, FBgn0086368). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:784746..788215. It has the cytological map location 1C4. Protein features are: Glycosyl transferase family 39/83; Glycosyltransferase 39-like; MIR motif; Protein O-mannosyl-transferase, C-terminal four TM domain. Its molecular function is described by: protein binding; dolichyl-phosphate-mannose-protein mannosyltransferase activity. It is involved in the biological process described with: sarcomere organization; muscle attachment; protein O-linked mannosylation; muscle organ development; ER-associated misfolded protein catabolic process; lipid glycosylation; somatic muscle development. 21 alleles are reported. The phenotypes of these alleles manifest in: organism subdivision; anterior-posterior subdivision of organism; adult tagma; integumentary system; extracellular region part; embryonic precursor cell of adult muscle; embryo; multi-tissue structure; somatic cell; adult abdomen; myofilament. The phenotypic classes of alleles include: visible; phenotype; flight defective; developmental rate defective; cell death defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages, during late pupal stages.  "
FBgn0050265	CG30265	-0.310026738	0.257366165	0.999936032	NA	SLC17A4;SLC17A3;SLC17A1;SLC17A5;SLC17A2;SLC17A6;SLC17A8;SLC17A7	high;high;high;moderate;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG30265 (FBgn0050265). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:22832456..22834580. It has the cytological map location 59B2. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain. Its molecular function is described by: transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; anion transport. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0038682	CG5835	-0.30981886	0.371650382	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG5835 (FBgn0038682). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:19148632..19153686. It has the cytological map location 91F4. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during early pupal stages.
FBgn0033423	CG1809	-0.309570899	0.353951046	0.999936032	NA	ALPI;ALPPL2;ALPP;ALPL	moderate;moderate;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1809 (FBgn0033423). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:9561638..9563871. It has the cytological map location 45F1. Protein features are: Alkaline phosphatase; Alkaline phosphatase, active site; Alkaline phosphatase-like, alpha/beta/alpha; Alkaline-phosphatase-like, core domain. Its molecular function is described by: alkaline phosphatase activity. It is involved in the biological process described with: dephosphorylation. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0028744	CG5033	-0.309327327	0.386310166	0.999936032	BOP1	BOP1;MIR7112	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5033 (FBgn0028744). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:17789679..17792448. It has the cytological map location 54E9. Protein features are: BOP1, N-terminal domain; WD repeat BOP1/Erb1; WD40 repeat; WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: ribonucleoprotein complex binding. It is involved in the biological process described with: regulation of hemocyte proliferation; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); positive regulation of multicellular organism growth. 9 alleles are reported. The phenotypes of these alleles manifest in: Z disc; sarcomere; ganglion mother cell; embryonic/larval neuroblast; mesothoracic tergum. The phenotypic classes of alleles include: visible; viable; lethal; lethal - all die during larval stage; neuroanatomy defective; small body. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages.  "
FBgn0052278	CG32278	-0.3093131	0.377190149	0.999936032	NA	TRMT5	low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32278 (FBgn0052278). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:3169286..3171767. It has the cytological map location 63B8. Its molecular function is unknown. It is involved in the biological process described with: sensory perception of pain. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 06-18 hour embryonic stages, during late pupal stages.  "
FBgn0011764	Dsp1	-0.309159002	0.390702613	0.999936032	NA	HMGB2;HMGB3;HMGB1;HMGB4;HMGB3P27;HMG20B;HMG20A	high;high;moderate;moderate;moderate;low;low	NA	NA	NA	NA
FBgn0032895	twit	-0.308952561	0.334957499	0.999936032	NA	NA	NA	NA	NA	NA	"The gene target of wit is referred to in FlyBase by the symbol Dmel\twit (CG9335, FBgn0032895). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:20852578..20857113. It has the cytological map location 38F2-38F3. Its molecular function is unknown. It is involved in the biological process described with: regulation of neurotransmitter secretion. 7 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval neuromuscular junction. The phenotypic classes of alleles include: fertile; neurophysiology defective; viable; lethal - all die during P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages.  "
FBgn0052194	CR32194	-0.308952561	0.334957499	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR32194 (FBgn0052194). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3L:18085305..18087058. It has the cytological map location 75B7. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported.
FBgn0031189	CG14618	-0.308898468	0.437883228	0.999936032	TRMT10A	TRMT10A;TRMT10C;TRMT10B	high;low;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14618 (FBgn0031189). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:22473698..22474998. It has the cytological map location 20C1. Protein features are: tRNA (guanine(9)-N(1))-methyltransferase TRM10; tRNA (guanine-N1-)-methyltransferase, eukaryotic; tRNA methyltransferase TRM10-type domain; tRNA methyltransferase TRMD/TRM10-type domain. Its molecular function is described by: methyltransferase activity. It is involved in the biological process described with: . 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0001091	Gapdh1	-0.308560207	0.357508308	0.999936032	NA	GAPDH;GAPDHS	high;moderate	NA	NA	NA	"The gene Glyceraldehyde 3 phosphate dehydrogenase 1 is referred to in FlyBase by the symbol Dmel\Gapdh1 (CG12055, FBgn0001091). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:7791901..7793380. It has the cytological map location 43E17. Protein features are: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, active site; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Glyceraldehyde-3-phosphate dehydrogenase, type I; Glyceraldehyde/Erythrose phosphate dehydrogenase family; NAD(P)-binding domain. Its molecular function is described by: glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity; NADP binding; NAD binding. It is involved in the biological process described with: somatic muscle development; glucose metabolic process; glycolytic process; myoblast fusion; oxidation-reduction process. 13 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval somatic muscle; embryonic myoblast. The phenotypic classes of alleles include: viable; flightless; locomotor behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of moderate expression.  Peak expression observed at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0033924	CG8613	-0.308462534	0.43035292	0.999936032	SPATA20	SPATA20	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8613 (FBgn0033924). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:14352231..14355674. It has the cytological map location 50F6. Protein features are: Domain of unknown function DUF255; Six-hairpin glycosidase-like; Spermatogenesis-associated protein 20; Thioredoxin-like fold. Its molecular function is described by: catalytic activity. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages, in adult male stages.  "
FBgn0019952	Orct	-0.308413003	0.400607903	0.999936032	NA	SLC22A4;SLC22A5;SLC22A13;SLC22A16	high;moderate;low;low	NA	transmembrane protein	NA	"The gene Organic cation transporter is referred to in FlyBase by the symbol Dmel\Orct (CG6331, FBgn0019952). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:24276260..24278792. It has the cytological map location 95F8. Protein features are: Major facilitator superfamily domain; Major facilitator,  sugar transporter-like. Its molecular function is described by: organic anion transmembrane transporter activity. It is involved in the biological process described with: apoptotic process; transmembrane transport. 5 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval fat body; lipid particle. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late larval stages.  "
FBgn0033451	CG1665	-0.308359383	0.369129086	0.999936032	NA	MARC1;MARC2	high;high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1665 (FBgn0033451). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:9839776..9841163. It has the cytological map location 46B4. Protein features are: MOSC, N-terminal beta barrel; Molybdenum cofactor sulfurase, C-terminal; Pyruvate kinase-like, insert domain. Its molecular function is described by: catalytic activity; pyridoxal phosphate binding; molybdenum ion binding. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0039561	mfrn	-0.308347746	0.378039967	0.999936032	NA	SLC25A37;SLC25A28	high;moderate	NA	NA	NA	"The gene mitoferrin is referred to in FlyBase by the symbol Dmel\mfrn (CG4963, FBgn0039561). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:27942796..27948021. It has the cytological map location 98B6. Protein features are: Mitochondrial carrier domain; Mitochondrial carrier protein; Mitochondrial substrate/solute carrier. Its molecular function is described by: iron ion transmembrane transporter activity. It is involved in the biological process described with: mitochondrial iron ion transport; multicellular organismal iron ion homeostasis; spermatid differentiation; mitochondrial transport; transmembrane transport. 14 alleles are reported. The phenotypes of these alleles manifest in: spermatozoon; elongation stage spermatid; mitochondrial derivative; spermatid cyst. The phenotypic classes of alleles include: some die during pupal stage; female fertile; viable; male sterile; phenotype; increased mortality; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0034491	Hsl	-0.308258185	0.421251407	0.999936032	NA	LIPE	high	NA	NA	NA	"The gene Hormone-sensitive lipase is referred to in FlyBase by the symbol Dmel\Hsl (CG11055, FBgn0034491). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:20257650..20261726. It has the cytological map location 56F11. Protein features are: Alpha/Beta hydrolase fold; Alpha/beta hydrolase fold-3; Hormone-sensitive lipase, N-terminal. Its molecular function is described by: lipase activity. It is involved in the biological process described with: triglyceride mobilization; cholesterol metabolic process; lipid catabolic process. 7 alleles are reported. The phenotypes of these alleles manifest in: lipid particle; embryonic/larval fat body. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0261843	pre-mod(mdg4)-W	-0.308230234	0.37911256	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\pre-mod(mdg4)-W (CG42775, FBgn0261843). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:21365609..21370249. It has the cytological map location 93D8-93D9. Protein features are: Zinc finger, FLYWCH-type. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  No temporal expression data available due to processing error.  This will be corrected the next time these data and summaries are processed."
FBgn0033808	CG4627	-0.308014693	0.426245043	0.999936032	NA	TMEM186	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4627 (FBgn0033808). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:13214706..13215760. It has the cytological map location 49F10. Protein features are: Transmembrane protein 186. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in adult female stages.  "
FBgn0025625	Sik2	-0.307720057	0.451506246	0.999936032	NA	SIK2;SIK1;LOC102724428	high;moderate;moderate	NA	NA	NA	"The gene Salt-inducible kinase 2 is referred to in FlyBase by the symbol Dmel\Sik2 (CG4290, FBgn0025625). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:2055310..2061915. It has the cytological map location 2C8. Protein features are: Protein kinase domain; Protein kinase, ATP binding site; Protein kinase-like domain; Salt-Inducible kinase, catalytic domain; Serine/threonine-protein kinase, active site. Its molecular function is described by: protein serine/threonine kinase activity; ATP binding. It is involved in the biological process described with: cellular response to hormone stimulus; intracellular signal transduction; protein phosphorylation; response to starvation. 11 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: stress response defective; viable; long lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0032669	CG15155	-0.30750913	0.462507882	0.999936032	NA	GLYATL3	low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15155 (FBgn0032669). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:18154851..18155942. It has the cytological map location 36E6. Protein features are: Acyl-CoA N-acyltransferase; FR47-like. Its molecular function is described by: transferase activity, transferring acyl groups other than amino-acyl groups. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0042101	CG18744	-0.307484187	0.377295844	0.999936032	NA	ARRDC2;ARRDC4;TXNIP;ARRDC3;ARRDC1;ARRDC5	moderate;moderate;moderate;moderate;low;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG18744 (FBgn0042101). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:7797078..7798771. It has the cytological map location 84E1. Protein features are: Arrestin C-terminal-like domain; Arrestin-like, N-terminal; Immunoglobulin E-set. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. The phenotypic class of allele includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, in adult female stages.  "
FBgn0262848	CR43212	-0.307347325	0.441104538	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CR43212 (FBgn0262848).The gene has a gene model, but the supporting evidence is inconclusive. It is a pseudogene_attribute from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is X:11595655..11597545. It has the cytological map location 10C9. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported."
FBgn0010198	RpS15Aa	-0.307309055	0.358776524	0.999936032	NA	RPS15A	high	NA	NA	NA	"The gene Ribosomal protein S15Aa is referred to in FlyBase by the symbol Dmel\RpS15Aa (CG2033, FBgn0010198). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is X:13335637..13337705. It has the cytological map location 11E11-11E12. Protein features are: Ribosomal protein S8. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: translation; cytoplasmic translation. 5 alleles are reported. The phenotypes of these alleles manifest in: Z disc; adult heart; embryonic/larval somatic muscle; sarcomere. The phenotypic classes of alleles include: lethal; lethal - all die during larval stage; viable; partially lethal - majority die; size defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0038861	CG7009	-0.307215639	0.42113926	0.999936032	NA	FTSJ1	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7009 (FBgn0038861). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:21132734..21133881. It has the cytological map location 93C1. Protein features are: Ribosomal RNA large subunit methyltransferase E; Ribosomal RNA methyltransferase FtsJ domain; S-adenosyl-L-methionine-dependent methyltransferase; tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase, Trm7. Its molecular function is described by: tRNA methyltransferase activity. It is involved in the biological process described with: cytoplasmic translation; tRNA methylation. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0024994	Csat	-0.307183891	0.383734025	0.999936032	NA	SLC35A2;SLC35A3;SLC35A1;SLC35A4	high;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene Csat is referred to in FlyBase by the symbol Dmel\Csat (CG2675, FBgn0024994). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:2701124..2703852. It has the cytological map location 3B2. Protein features are: Nucleotide-sugar transporter. Its molecular function is described by: sugar:proton symporter activity; UDP-galactose transmembrane transporter activity; UDP-N-acetylgalactosamine transmembrane transporter activity. It is involved in the biological process described with: UDP-galactose transport; galactose transport; UDP-N-acetylgalactosamine transport. 7 alleles are reported. The phenotype of these alleles manifest in: adult abdomen. The phenotypic classes of alleles include: lethal; body color defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0032819	CG10463	-0.307111074	0.431437802	0.999936032	DUS3L	DUS3L	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10463 (FBgn0032819). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:19758879..19760986. It has the cytological map location 38A2. Protein features are: Aldolase-type TIM barrel; DUS-like, FMN-binding domain; Zinc finger, CCCH-type; tRNA-dihydrouridine synthase; tRNA-dihydrouridine synthase, conserved site. Its molecular function is described by: tRNA dihydrouridine synthase activity; metal ion binding; flavin adenine dinucleotide binding. It is involved in the biological process described with: tRNA processing; oxidation-reduction process. 4 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: lethal; body color defective; viable; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0263240	Coop	-0.306867924	0.4653094	0.999936032	NA	NA	NA	DNA-binding with transcription factor activity(BESS)	NA	NA	"The gene Corepressor of Pangolin is referred to in FlyBase by the symbol Dmel\Coop (CG1621, FBgn0263240). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:7490836..7492589. It has the cytological map location 43C5. Protein features are: BESS motif; MADF domain. Its molecular function is described by: DNA binding; transcription factor binding; RNA polymerase II transcription corepressor activity. It is involved in the biological process described with: negative regulation of transcription from RNA polymerase II promoter; negative regulation of Wnt signaling pathway. 18 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: viable; visible; fertile; lethal."
FBgn0000447	Dhod	-0.306648139	0.375438433	0.999936032	NA	DHODH	high	NA	transmembrane protein	NA	"The gene Dihydroorotate dehydrogenase is referred to in FlyBase by the symbol Dmel\Dhod (CG9741, FBgn0000447). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:8651391..8652916. It has the cytological map location 85A5. Protein features are: Aldolase-type TIM barrel; Dihydroorotate dehydrogenase domain; Dihydroorotate dehydrogenase, class 2; Dihydroorotate dehydrogenase, conserved site. Its molecular function is described by: dihydroorotate dehydrogenase activity. It is involved in the biological process described with: oxidation-reduction process; 'de novo' pyrimidine nucleobase biosynthetic process. 38 alleles are reported. The phenotypes of these alleles manifest in: eye; wing hair; arista; wing. The phenotypic classes of alleles include: lethal; female sterile; viable; visible; female fertile; wild-type. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0029905	Nf-YC	-0.306582729	0.422895369	0.999936032	NA	NFYC;POLE4;CHRAC1	high;low;low	DNA-binding with transcription factor activity(CBFA_NFYB_domain)	NA	NA	"The gene Nuclear factor Y-box C is referred to in FlyBase by the symbol Dmel\Nf-YC (CG3075, FBgn0029905). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:6818178..6820919. It has the cytological map location 6D3. Protein features are: Histone-fold; Transcription factor CBF/NF-Y/archaeal histone domain; Transcriptional activator NFYC/HAP5 subunit. Its molecular function is described by: transcription factor activity, sequence-specific DNA binding; sequence-specific DNA binding; protein heterodimerization activity. It is involved in the biological process described with: axon guidance; regulation of transcription, DNA-templated. 17 alleles are reported. The phenotypes of these alleles manifest in: lamina; wing; wing vein. The phenotypic classes of alleles include: lethal - all die before end of P-stage; some die during pharate adult stage; lethal; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0031518	CG3277	-0.306275608	0.420525217	0.999936032	NA	FGFR4;RET;FGFR1;FGFR3;FGFR2;TEK;TIE1	moderate;moderate;moderate;moderate;moderate;high;high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3277 (FBgn0031518). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:3304100..3317418. It has the cytological map location 23E3. Protein features are: Protein kinase domain; Protein kinase, ATP binding site; Protein kinase-like domain; Serine-threonine/tyrosine-protein kinase, catalytic domain; Tyrosine-protein kinase, active site; Tyrosine-protein kinase, catalytic domain. Its molecular function is described by: protein tyrosine kinase activity; ATP binding. It is involved in the biological process described with: protein phosphorylation. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0031631	CG3225	-0.306171437	0.408935405	0.999936032	DHX35	DHX35	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3225 (FBgn0031631). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:4815613..4818245. It has the cytological map location 25A6-25A7. Protein features are: DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site; Domain of unknown function DUF1605; Helicase superfamily 1/2, ATP-binding domain; Helicase, C-terminal; Helicase-associated domain; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: ATP-dependent RNA helicase activity; RNA binding; helicase activity. It is involved in the biological process described with: RNA processing; mRNA splicing, via spliceosome. 5 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-12 hour embryonic stages, during early pupal stages, in adult male stages.  "
FBgn0041181	Tep3	-0.306171437	0.408935405	0.999936032	NA	CD109;C3;C4B;C4A;A2ML1;C5;A2M	moderate;low;moderate;low;low;low;moderate	NA	transmembrane protein	NA	"The gene Thioester-containing protein 3 is referred to in FlyBase by the symbol Dmel\Tep3 (CG7068, FBgn0041181). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:7702805..7710690. It has the cytological map location 28C1. Protein features are: Alpha-2-macroglobulin; Alpha-2-macroglobulin, N-terminal; Alpha-2-macroglobulin, N-terminal 2; Alpha-2-macroglobulin, conserved site; Alpha-2-macroglobulin, thiol-ester bond-forming; Alpha-macroglobulin complement component; Alpha-macroglobulin, receptor-binding; Immunoglobulin-like fold; Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid. Its molecular function is described by: endopeptidase inhibitor activity. It is involved in the biological process described with: defense response to Gram-positive bacterium; phagocytosis; defense response to other organism. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile; immune response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during late pupal stages.  "
FBgn0035228	CG12091	-0.306044115	0.370742557	0.999936032	PPTC7	PPTC7	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12091 (FBgn0035228). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:1534929..1536835. It has the cytological map location 62A3. Protein features are: PPM-type phosphatase domain. Its molecular function is described by: protein serine/threonine phosphatase activity; phosphoprotein phosphatase activity. It is involved in the biological process described with: protein dephosphorylation. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: female semi-sterile; viable; short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0051547	NKCC	-0.306018113	0.418282914	0.999936032	NA	SLC12A3;SLC12A1;SLC12A2	moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene sodium potassium chloride cotransporter is referred to in FlyBase by the symbol Dmel\NKCC (CG31547, FBgn0051547). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:5489505..5502702. It has the cytological map location 83A5-83A6. Protein features are: Amino acid permease/ SLC12A domain; P-type ATPase,  transmembrane domain; SLC12A transporter family; SLC12A transporter, C-terminal. Its molecular function is described by: cation:chloride symporter activity; amino acid transmembrane transporter activity. It is involved in the biological process described with: amino acid transmembrane transport. 12 alleles are reported. The phenotype of these alleles manifest in: l-LNv neuron. The phenotypic classes of alleles include: circadian rhythm defective; viable; neurophysiology defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0030687	CG17209	-0.305815585	0.408235792	0.999936032	POLR3A	POLR3A	high	DNA-binding with transcription factor activity	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17209 (FBgn0030687). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:15762956..15769514. It has the cytological map location 13E14-13E15. Protein features are: DNA-directed RNA polymerase III subunit RPC1, C-terminal; DNA-directed RNA polymerase III subunit RPC1, N-terminal; RNA polymerase Rpb1, domain 1; RNA polymerase Rpb1, domain 3; RNA polymerase Rpb1, domain 4; RNA polymerase Rpb1, domain 5; RNA polymerase, N-terminal; RNA polymerase, alpha subunit. Its molecular function is described by: RNA polymerase III activity; DNA binding. It is involved in the biological process described with: transcription, DNA-templated. 6 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: some die during pupal stage; partially lethal - majority die; visible; viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed in adult female stages.  "
FBgn0036773	CG13698	-0.305780519	0.465943122	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG13698 (FBgn0036773). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:18088417..18106149. It has the cytological map location 75B7-75B9. Its molecular function is unknown. The biological processes in which it is involved are not known. 12 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages.
FBgn0034723	CG13506	-0.305703071	0.376079879	0.999936032	NA	SIGIRR;IL18R1;IL1R1;IL18RAP;IL1RL2;IL1RAPL1;IL1RL1;IL1RAP;IL1RAPL2;USH2A;KIRREL2;SDK1;LRIT3;PAPLN;LRIT1;IGSF9B;KIRREL3;KIRREL	low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13506 (FBgn0034723). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:22383134..22394015. It has the cytological map location 58D4. Protein features are: Immunoglobulin I-set; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold. Its molecular function is unknown. The biological processes in which it is involved are not known. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die during embryonic stage; lethal; flightless; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages.  "
FBgn0045823	vsg	-0.305459992	0.362246305	0.999936032	NA	CD164;TMEM123;CD164L2	high;moderate;moderate	NA	transmembrane protein	NA	"The gene visgun is referred to in FlyBase by the symbol Dmel\vsg (CG16707, FBgn0045823). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is 3L:9714324..9717716. It has the cytological map location 67C5. Protein features are: CD164-related protein. Its molecular function is described by: . It is involved in the biological process described with: regulation of cell proliferation; multicellular organism reproduction; learning or memory; behavioral response to ethanol; olfactory learning; long-term memory. 12 alleles are reported. The phenotype of these alleles manifest in: melanotic mass. The phenotypic classes of alleles include: memory defective; fertile; viable; chemical sensitive; melanotic mass phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed within 06-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0263667	Lpt	-0.305136955	0.467844323	0.999936032	NA	KMT2D;KMT2C	moderate;moderate	DNA-binding with transcription factor activity	NA	NA	"The gene Lost PHDs of trr is referred to in FlyBase by the symbol Dmel\Lpt (CG5591, FBgn0263667). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:23898561..23903661. It has the cytological map location 60A9. Protein features are: High mobility group box domain; Zinc finger, FYVE/PHD-type; Zinc finger, PHD-finger; Zinc finger, PHD-type; Zinc finger, RING-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: ligand-dependent nuclear receptor transcription coactivator activity; chromatin binding; zinc ion binding; histone binding. It is involved in the biological process described with: positive regulation of histone H3-K9 trimethylation; histone H3-K4 methylation; positive regulation of transcription from RNA polymerase II promoter; ecdysis, chitin-based cuticle; ecdysone receptor-mediated signaling pathway; phagocytosis; imaginal disc-derived wing vein morphogenesis; imaginal disc-derived wing vein specification; cellular response to ecdysone. 10 alleles are reported. The phenotypes of these alleles manifest in: non-connected functional system; embryo; eye; eo-type sensillum; anatomical space; eo support cell; embryonic/larval hemocoel; prothoracic metatarsus; sensory system; row. The phenotypic classes of alleles include: increased mortality; phenotype; increased mortality during development; visible."
FBgn0046114	Gclm	-0.305018767	0.361746332	0.999936032	NA	GCLM	high	NA	NA	NA	"The gene Glutamate-cysteine ligase modifier subunit is referred to in FlyBase by the symbol Dmel\Gclm (CG4919, FBgn0046114). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:22685006..22686510. It has the cytological map location 94C1. Protein features are: Glutamate--cysteine ligase regulatory subunit; NADP-dependent oxidoreductase domain. Its molecular function is described by: enzyme regulator activity; glutamate-cysteine ligase catalytic subunit binding; enzyme binding. It is involved in the biological process described with: learning or memory; behavioral response to ethanol; detoxification of arsenic-containing substance; glutathione biosynthetic process; long-term memory; olfactory learning; positive regulation of glutamate-cysteine ligase activity; cellular response to DNA damage stimulus. 17 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: chemical sensitive; viable; fertile; memory defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-06 and 12-18 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0039532	Mtl	-0.304838022	0.410987799	0.999936032	NA	RHOG;RAC1;RAC3;RAC2;RHOH;CDC42;RHOJ	high;low;low;low;moderate;low;low	NA	NA	NA	"The gene Mig-2-like is referred to in FlyBase by the symbol Dmel\Mtl (CG5588, FBgn0039532). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:27636412..27639871. It has the cytological map location 98A13. Protein features are: P-loop containing nucleoside triphosphate hydrolase; Small GTP-binding protein domain; Small GTPase superfamily; Small GTPase superfamily, Rho type. Its molecular function is described by: GTPase activity; GTP binding. It is involved in the biological process described with 16 unique terms, many of which group under: organelle organization; single-organism organelle organization; nervous system development; cellular response to DNA damage stimulus; wound healing; salivary gland morphogenesis; small GTPase mediated signal transduction; protein phosphorylation; response to wounding; cell morphogenesis; protein metabolic process; establishment of ommatidial planar polarity; positive regulation of response to stimulus; hemopoiesis; supramolecular fiber organization; head involution; tube morphogenesis; Ras protein signal transduction. 15 alleles are reported. The phenotypes of these alleles manifest in: presumptive embryonic salivary gland; ommatidium; wing hair; eye; longitudinal connective; adult mushroom body. The phenotypic classes of alleles include: wild-type; planar polarity defective; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed during early pupal stages.  "
FBgn0036423	CG3919	-0.304457715	0.439379225	0.999936032	NA	NA	NA	DNA-binding with transcription factor activity(BESS)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3919 (FBgn0036423). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:14410626..14412732. It has the cytological map location 70D7. Protein features are: BESS motif; MADF domain. Its molecular function is described by: DNA binding. The biological processes in which it is involved are not known. 8 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0032919	CG9253	-0.30422896	0.404033847	0.999936032	NA	DDX47;DDX49	high;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9253 (FBgn0032919). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:21143229..21145146. It has the cytological map location 39A4. Protein features are: ATP-dependent RNA helicase DEAD-box, conserved site; DEAD/DEAH box helicase domain; Helicase superfamily 1/2, ATP-binding domain; Helicase, C-terminal; P-loop containing nucleoside triphosphate hydrolase; RNA helicase, DEAD-box type, Q motif. Its molecular function is described by: ATP binding; ATP-dependent RNA helicase activity; nucleic acid binding. It is involved in the biological process described with: rRNA processing; RNA secondary structure unwinding. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; some die during pupal stage; lethal - all die during larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0001323	knrl	-0.303868505	0.469393553	0.999936032	NA	NR1H2	low	DNA-binding with transcription factor activity(zf-C4)	NA	NA	"The gene knirps-like is referred to in FlyBase by the symbol Dmel\knrl (CG4761, FBgn0001323). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:20597141..20620659. It has the cytological map location 77D4-77E1. Protein features are: Zinc finger, NHR/GATA-type; Zinc finger, nuclear hormone receptor-type. Its molecular function is described by: zinc ion binding; sequence-specific DNA binding; transcription factor activity, sequence-specific DNA binding. It is involved in the biological process described with: regulation of mitotic nuclear division; branched duct epithelial cell fate determination, open tracheal system; epithelial cell migration, open tracheal system; regulation of tube size, open tracheal system; open tracheal system development; negative regulation of transcription, DNA-templated. 8 alleles are reported. The phenotypes of these alleles manifest in: wing; metathoracic femur; embryonic dorsal epidermis; embryo. The phenotypic classes of alleles include: visible; mitotic cell cycle defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-18 hour embryonic stages, during late pupal stages.  "
FBgn0066084	RpL41	-0.303774537	0.364435697	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Ribosomal protein L41 is referred to in FlyBase by the symbol Dmel\RpL41 (CG30425, FBgn0066084). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:24903416..24903935. It has the cytological map location 60E5. Protein features are: Ribosomal protein L41. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: translation; cytoplasmic translation. 11 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0036889	CG14100	-0.303551885	0.410918702	0.999936032	RNMTL1	MRM3	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14100 (FBgn0036889). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:19589072..19590524. It has the cytological map location 76B8. Protein features are: 50S ribosomal protein L30e-like; Alpha/beta knot methyltransferases; RNA 2-O ribose methyltransferase, substrate binding; tRNA (guanine-N1-)-methyltransferase, N-terminal; tRNA/rRNA methyltransferase, SpoU type. Its molecular function is described by: RNA binding; RNA methyltransferase activity. It is involved in the biological process described with: RNA processing. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0029522	CG13373	-0.3033158	0.462004308	0.999936032	NA	SIVA1	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG13373 (FBgn0029522). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:476984..478191. It has the cytological map location 1B4. Protein features are: Siva. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0031195	CG17600	-0.3033158	0.462004308	0.999936032	NA	MS4A13;MS4A18;TMEM212;MS4A8;MS4A6E;MS4A2;MS4A4A;MS4A3;MS4A7;MS4A1;MS4A14;MS4A5;MS4A6A;MS4A4E;MS4A12;MS4A10;MS4A15	low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG17600 (FBgn0031195). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is X:22515197..22542024. It has the cytological map location 20C1. Protein features are: CD20-like family; Membrane-spanning 4-domains subfamily A. Its molecular function is unknown. The biological processes in which it is involved are not known. 17 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile; lethal; lethal - all die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed during late pupal stages.
FBgn0025109	Bem46	-0.30331407	0.387289258	0.999936032	NA	ABHD13	high	NA	transmembrane protein	NA	"The gene Bem46 is referred to in FlyBase by the symbol Dmel\Bem46 (CG18642, FBgn0025109). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:2988116..2990075. It has the cytological map location 23C4. Protein features are: Alpha/Beta hydrolase fold; Serine aminopeptidase, S33; Serine hydrolase FSH. Its molecular function is described by: . It is involved in the biological process described with: . 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, in stages of adults of both sexes.  "
FBgn0015513	mbc	-0.303265432	0.395133397	0.999936032	DOCK1	DOCK1;DOCK2;DOCK5;DOCK3;DOCK4	high;moderate;moderate;low;low	NA	NA	NA	"The gene myoblast city is referred to in FlyBase by the symbol Dmel\mbc (CG10379, FBgn0015513). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:23781765..23801634. It has the cytological map location 95B5-95B7. Protein features are: Armadillo-like helical; C2 domain; DHR-1 domain; DHR-2 domain; Dedicator of cytokinesis; Dedicator of cytokinesis, C-terminal; Dedicator of cytokinesis, N-terminal domain; SH3 domain. Its molecular function is described by: Rac guanyl-nucleotide exchange factor activity; protein binding. It is involved in the biological process described with 13 unique terms, many of which group under: cytoskeleton organization; cellular component organization or biogenesis; positive regulation of hydrolase activity; morphogenesis of embryonic epithelium; epithelium migration; larval visceral muscle development; muscle attachment; single organism signaling; growth; positive regulation of catalytic activity; tube development. 64 alleles are reported. The phenotypes of these alleles manifest in: female germline cyst; non-connected functional system; embryonic/larval anterior Malpighian tubule; circular visceral muscle fiber; organelle; membrane-bounded organelle; reticular neuropil associated glial cell; presumptive embryonic/larval muscle system; ovary; fused midgut primordium. The phenotypic classes of alleles include: lethal - all die before end of first instar larval stage; phenotype; increased mortality during development; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0030369	Cyp318a1	-0.302746072	0.456526413	0.999936032	NA	CYP4Z1;CYP4B1;CYP4X1;CYP46A1	moderate;moderate;moderate;high	NA	transmembrane protein	NA	"The gene Cyp318a1 is referred to in FlyBase by the symbol Dmel\Cyp318a1 (CG1786, FBgn0030369). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:12032632..12035283. It has the cytological map location 11A2. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group IV; Cytochrome P450, conserved site. Its molecular function is described by: iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; monooxygenase activity; heme binding. It is involved in the biological process described with: oxidation-reduction process. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; lethal - all die during P-stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0037891	CG5214	-0.302646824	0.37082819	0.999936032	NA	DLST	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5214 (FBgn0037891). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:11244302..11246862. It has the cytological map location 86D9. Protein features are: 2-oxo acid dehydrogenase, lipoyl-binding site; 2-oxoacid dehydrogenase acyltransferase, catalytic domain; Biotin/lipoyl attachment; Dihydrolipoamide succinyltransferase; Single hybrid motif. Its molecular function is described by: dihydrolipoyllysine-residue succinyltransferase activity. It is involved in the biological process described with: negative regulation of neuroblast proliferation; tricarboxylic acid cycle; cellular respiration. 6 alleles are reported. The phenotypes of these alleles manifest in: neuroblast; mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: visible; increased mortality during development; phenotype; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0036289	CG10657	-0.302508906	0.399454902	0.999936032	NA	CLVS1;RLBP1;CLVS2;TTPAL;TTPA	high;moderate;moderate;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10657 (FBgn0036289). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:12491830..12497216. It has the cytological map location 69C3. Protein features are: CRAL-TRIO lipid binding domain; CRAL/TRIO, N-terminal domain; Cellular retinaldehyde binding/alpha-tocopherol transport. Its molecular function is described by: transporter activity. It is involved in the biological process described with: transport; lateral inhibition. 4 alleles are reported. The phenotypes of these alleles manifest in: chaeta; trichogen cell. The phenotypic classes of alleles include: fertile; flight defective; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages.  "
FBgn0263510	nclb	-0.301786613	0.37933288	0.999936032	NA	PWP1	high	DNA-binding with transcription factor activity	NA	NA	"The gene no child left behind is referred to in FlyBase by the symbol Dmel\nclb (CG6751, FBgn0263510). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:10875748..10877296. It has the cytological map location 47C5. Protein features are: Six-bladed beta-propeller, TolB-like; WD40 repeat; WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: chromatin DNA binding. It is involved in the biological process described with: ovarian fusome organization; male gonad development; germ cell development; male germ-line stem cell population maintenance; ovarian follicle cell development; regulation of gene expression. 9 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; follicle cell; female germline cell; egg chamber; testis; nurse cell; male germline cell; ovary; trichogen cell; individualization stage spermatid. The phenotypic classes of alleles include: sterile; lethal; increased mortality; phenotype."
FBgn0086706	pix	-0.301763627	0.373015535	0.999936032	NA	ABCE1	high	NA	NA	NA	"The gene pixie is referred to in FlyBase by the symbol Dmel\pix (CG5651, FBgn0086706). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:8972056..8974765. It has the cytological map location 66E6. Protein features are: 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; 4Fe-4S ferredoxin-type, iron-sulphur binding domain; AAA+ ATPase domain; ABC transporter, conserved site; ABC transporter-like; P-loop containing nucleoside triphosphate hydrolase; RLI, domain 1; RLI1; RNase L inhibitor RLI, possible metal-binding domain. Its molecular function is described by: ATPase activity; iron ion binding; protein binding; translation initiation factor binding; ATP binding; ribosomal small subunit binding. It is involved in the biological process described with: translational termination; translational initiation; nuclear-transcribed mRNA catabolic process, non-stop decay; translation; cell growth; ribosome disassembly; negative regulation of neuron apoptotic process; ribosomal subunit export from nucleus. 13 alleles are reported. The phenotypes of these alleles manifest in: chaeta; wing; ommatidium; wing disc; interommatidial bristle; macrochaeta. The phenotypic classes of alleles include: body size defective; cell number defective; phenotype; viable; lethal - all die before end of first instar larval stage; some die during P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0011584	Trp1	-0.301746724	0.378133006	0.999936032	NA	SEC62	high	NA	transmembrane protein	NA	"The gene Translocation protein 1 is referred to in FlyBase by the symbol Dmel\Trp1 (CG4758, FBgn0011584). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 2L:10009381..10013170. It has the cytological map location 30F5. Protein features are: Translocation protein Sec62; Winged helix-turn-helix DNA-binding domain. Its molecular function is described by: protein transporter activity. It is involved in the biological process described with: posttranslational protein targeting to membrane, translocation. 5 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; myofibril; embryonic/larval hemocyte; mesothoracic tergum; wing. The phenotypic classes of alleles include: uncoordinated; body color defective; visible; viable; flight defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 06-18 hour embryonic stages.  "
FBgn0037942	CG14721	-0.301485171	0.39054259	0.999936032	TPK1	TPK1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14721 (FBgn0037942). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:11735447..11736877. It has the cytological map location 86E17. Protein features are: Thiamin pyrophosphokinase; Thiamin pyrophosphokinase, catalytic domain; Thiamin pyrophosphokinase, vitamin B1-binding domain. Its molecular function is described by: thiamine binding; ATP binding; thiamine diphosphokinase activity. It is involved in the biological process described with: thiamine metabolic process; thiamine diphosphate biosynthetic process. 5 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; tormogen cell. The phenotypic classes of alleles include: lethal; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed in adult male stages.  "
FBgn0051054	CR31054	-0.301400214	0.221374682	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR31054 (FBgn0051054). It is a pseudogene_attribute from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3R:27960768..27961476. It has the cytological map location 98B6. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0086917	spok	-0.301400214	0.221374682	0.999936032	NA	CYP2C8;CYP2C18;CYP2E1;CYP1A2;CYP2R1;CYP2F1;CYP1B1	moderate;moderate;high;high;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene spookier is referred to in FlyBase by the symbol Dmel\spok (CG41624, FBgn0086917). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:3322810..3354486. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Its molecular function is described by: oxidoreductase activity; heme binding; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. It is involved in the biological process described with: oxidation-reduction process; ecdysone biosynthetic process; molting cycle, chitin-based cuticle. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die before end of first instar larval stage; some die during first instar larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0031630	CG15629	-0.301343296	0.467916472	0.999936032	NA	RDH10;HSD17B11;SDR16C5;DHRS3;HSD17B13	high;moderate;moderate;moderate;moderate	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG15629 (FBgn0031630). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:4813009..4815891. It has the cytological map location 25A6. Protein features are: NAD(P)-binding domain; Short-chain dehydrogenase/reductase SDR. Its molecular function is unknown. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages.
FBgn0003159	CG2841	-0.301057947	0.386648081	0.999936032	NA	COBLL1	low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG2841 (FBgn0003159). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (2 unique). Gene sequence location is X:2344949..2366356. It has the cytological map location 3A1-3A2. Its molecular function is described by: . It is involved in the biological process described with: . 9 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0266768	CR45233	-0.30102558	0.304881013	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45233 (FBgn0266768). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3L:14410117..14410698. It has the cytological map location 70D7. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0010391	Gtp-bp	-0.300974366	0.375384044	0.999936032	NA	SRPRA	high	NA	NA	NA	"The gene GTP-binding protein is referred to in FlyBase by the symbol Dmel\Gtp-bp (CG2522, FBgn0010391). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:11126877..11129087. It has the cytological map location 10A6. Protein features are: AAA+ ATPase domain; Longin-like domain; P-loop containing nucleoside triphosphate hydrolase; Signal recognition particle receptor, alpha subunit, N-terminal; Signal recognition particle, SRP54 subunit, GTPase domain; Signal recognition particle, SRP54 subunit, helical bundle. Its molecular function is described by: GTP binding; signal recognition particle binding; GTPase activity; RNA binding. It is involved in the biological process described with: SRP-dependent cotranslational protein targeting to membrane; regulation of protein secretion; axonogenesis. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: pain response defective; viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 06-18 hour embryonic stages.  "
FBgn0261608	RpL37A	-0.300915778	0.367357401	0.999936032	NA	RPL37A	high	NA	NA	NA	"The gene Ribosomal protein L37A is referred to in FlyBase by the symbol Dmel\RpL37A (CG5827, FBgn0261608). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:5070957..5072055. It has the cytological map location 25C4. Protein features are: Ribosomal protein L37ae; Ribosomal protein L37ae/L37e; Zinc-binding ribosomal protein. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: translation; cytoplasmic translation. 7 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval somatic muscle; Z disc; macrochaeta; sarcomere. The phenotypic classes of alleles include: some die during larval stage; increased mortality during development; phenotype; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed within 00-12 hour embryonic stages, during early larval stages.  "
FBgn0028988	Spn42Dd	-0.300869445	0.464292802	0.999936032	NA	SERPINB4;SERPINC1;SERPINB6;SERPINE2;SERPINE3;SERPINE1;SERPINI1;SERPINB12;SERPINB13;SERPINB3;SERPINB1;SERPINI2;SERPINB9;SERPINB10;SERPINB2;SERPINA10;SERPINB11;SERPINB5;SERPINB8;SERPINB7	high;moderate;moderate;moderate;moderate;moderate;moderate;moderate;low;low;low;low;low;low;low;moderate;low;moderate;moderate;low	NA	NA	NA	"The gene Serpin 42Dd is referred to in FlyBase by the symbol Dmel\Spn42Dd (CG9456, FBgn0028988). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:6883280..6884873. It has the cytological map location 42D6. Protein features are: Serpin domain; Serpin family. Its molecular function is described by: serine-type endopeptidase inhibitor activity. It is involved in the biological process described with: negative regulation of proteolysis; defense response to fungus; regulation of antimicrobial peptide production; multicellular organism reproduction; negative regulation of endopeptidase activity. 7 alleles are reported. The phenotypes of these alleles manifest in: Z disc; myofibril; sarcomere. The phenotypic classes of alleles include: immune response defective; viable; flightless. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during late larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0037138	P5CDh1	-0.300450678	0.443043771	0.999936032	ALDH4A1	ALDH4A1	high	NA	NA	NA	"The gene delta-1-Pyrroline-5-carboxylate dehydrogenase 1 is referred to in FlyBase by the symbol Dmel\P5CDh1 (CG7145, FBgn0037138). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is 3L:21836665..21841356. It has the cytological map location 78F4. Protein features are: Aldehyde dehydrogenase N-terminal domain; Aldehyde dehydrogenase domain; Aldehyde dehydrogenase, cysteine active site; Aldehyde dehydrogenase, glutamic acid active site; Aldehyde/histidinol dehydrogenase; Delta-1-pyrroline-5-carboxylate dehydrogenase. Its molecular function is described by: 1-pyrroline-5-carboxylate dehydrogenase activity. It is involved in the biological process described with: mitochondrion organization; proline metabolic process; proline catabolic process to glutamate; oxidation-reduction process. 19 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval midgut; mitochondrion. The phenotypic classes of alleles include: body size defective; visible; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0041150	hoe1	-0.300426863	0.461068659	0.999936032	NA	OCA2	high	NA	transmembrane protein	NA	"The gene hoepel1 is referred to in FlyBase by the symbol Dmel\hoe1 (CG12787, FBgn0041150). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (4 unique). Gene sequence location is 2L:4908581..4932384. It has the cytological map location 25B3. Protein features are: Citrate transporter-like domain. Its molecular function is unknown. It is involved in the biological process described with: transmembrane transport. 12 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0010774	Ref1	-0.300254833	0.380290806	0.999936032	NA	ALYREF	high	NA	NA	NA	"The gene RNA and export factor binding protein 1 is referred to in FlyBase by the symbol Dmel\Ref1 (CG1101, FBgn0010774). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:7077904..7080387. It has the cytological map location 84B2. Protein features are: Chromatin target of PRMT1 protein, C-terminal; RNA recognition motif domain. Its molecular function is described by: mRNA binding; transcription coactivator activity; nucleic acid binding. It is involved in the biological process described with: mRNA splicing, via spliceosome. 7 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: fertile; phenotype; viable; female fertile; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-18 hour embryonic stages, in adult female stages.  "
FBgn0031692	TpnC25D	-0.300214473	0.411210677	0.999936032	NA	CALM1;CALML3;CALML4;CABP4;CALM3;CABP5;CALM2;CALML5;CABP7;CABP1;CABP2;CALN1;CALML6;CALB1	moderate;moderate;low;moderate;low;moderate;low;low;moderate;moderate;moderate;moderate;moderate;low	NA	NA	NA	"The gene Troponin C at 25D is referred to in FlyBase by the symbol Dmel\TpnC25D (CG6514, FBgn0031692). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:5216701..5219053. It has the cytological map location 25D1. Protein features are: EF-Hand 1, calcium-binding site; EF-hand domain; EF-hand domain pair. Its molecular function is described by: calcium ion binding. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0037329	POLDIP2	-0.300056376	0.400043644	0.999936032	NA	POLDIP2;FBXO3	high;moderate	DNA-binding with transcription factor activity	NA	NA	"The gene Polymerase (DNA-directed), delta interacting protein 2 is referred to in FlyBase by the symbol Dmel\POLDIP2 (CG12162, FBgn0037329). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:5467778..5469566. It has the cytological map location 83A4. Protein features are: ApaG domain; Hemimethylated DNA-binding domain. Its molecular function is described by: DNA binding. The biological processes in which it is involved are not known. 5 alleles are reported. The phenotypes of these alleles manifest in: myofibril; sarcomere. The phenotypic classes of alleles include: fertile; viable; flight defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed in adult male stages.  "
FBgn0003278	RpI135	-0.300030865	0.442297694	0.999936032	NA	POLR1B	high	NA	NA	NA	"The gene RNA polymerase I 135kD subunit is referred to in FlyBase by the symbol Dmel\RpI135 (CG4033, FBgn0003278). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:404285..407969. It has the cytological map location 21C2. Protein features are: DNA-directed RNA polymerase I subunit RPA2, domain 4; DNA-directed RNA polymerase, subunit 2; DNA-directed RNA polymerase, subunit 2, domain 6; RNA polymerase Rpb2, domain 2; RNA polymerase Rpb2, domain 3; RNA polymerase Rpb2, domain 7; RNA polymerase, beta subunit, conserved site; RNA polymerase, beta subunit, protrusion. Its molecular function is described by: DNA binding; RNA polymerase I activity; ribonucleoside binding. It is involved in the biological process described with: positive regulation of cell size; transcription, DNA-templated; cell growth. 8 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval fat body; embryonic/larval neuroblast; ganglion mother cell; mesothoracic tergum; embryonic/larval hemocyte. The phenotypic classes of alleles include: visible; increased mortality during development; phenotype; lethal - all die before end of P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 06-12 hour embryonic stages, during early larval stages.  "
FBgn0015001	iotaTry	-0.300003913	0.369447083	0.999936032	NA	PRSS36;PRSS53;GZMB;KLK14	low;low;low;low	NA	NA	NA	"The gene ‘_Trypsin is referred to in FlyBase by the symbol Dmel\‘_Try (CG7754, FBgn0015001). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:11356720..11357537. It has the cytological map location 47F5. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: short lived; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during late larval stages.  "
FBgn0038590	CG12320	-0.299879385	0.457887764	0.999936032	AAR2	AAR2	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12320 (FBgn0038590). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:18251069..18252734. It has the cytological map location 90F10. Protein features are: A1 cistron-splicing factor, AAR2; AAR2, C-terminal; AAR2, N-terminal. Its molecular function is unknown. It is involved in the biological process described with: spliceosomal tri-snRNP complex assembly. 4 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.  "
FBgn0028379	fan	-0.299870864	0.246111928	0.999936032	NA	VAPB;VAPA;MOSPD3	moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene farinelli is referred to in FlyBase by the symbol Dmel\fan (CG7919, FBgn0028379). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:8109132..8110043. It has the cytological map location 66B6. Protein features are: Immunoglobulin-like fold; Major sperm protein (MSP) domain; PapD-like; Vesicle-associated membrane-protein-associated protein. Its molecular function is unknown. It is involved in the biological process described with: sperm individualization. 8 alleles are reported. The phenotype of these alleles manifest in: cystic bulge. The phenotypic classes of alleles include: fertile; viable; semi-sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed in adult male stages.  "
FBgn0050493	CG30493	-0.299660905	0.40478026	0.999936032	COQ9	COQ9	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG30493 (FBgn0050493). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:7699253..7703501. It has the cytological map location 43E11. Protein features are: COQ9; Ubiquinone biosynthesis protein COQ9. Its molecular function is described by: lipid binding. It is involved in the biological process described with: ubiquinone biosynthetic process. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: flight defective; viable; lethal; lethal - all die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed in adult male stages.
FBgn0033132	Tsp42Ej	-0.299616517	0.467684963	0.999936032	NA	TSPAN16;TSPAN19;TSPAN6	low;low;low	NA	transmembrane protein	NA	"The gene Tetraspanin 42Ej is referred to in FlyBase by the symbol Dmel\Tsp42Ej (CG12143, FBgn0033132). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:7040136..7042762. It has the cytological map location 42E5. Protein features are: Tetraspanin, EC2 domain; Tetraspanin/Peripherin. Its molecular function is described by: . It is involved in the biological process described with: cellular response to high light intensity; cell surface receptor signaling pathway; endocytosis. 11 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; retina. The phenotypic classes of alleles include: fertile; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0023516	Pex5	-0.299576939	0.387509832	0.999936032	PEX5	PEX5;PEX5L	high;moderate	NA	transmembrane protein	NA	"The gene Peroxin 5 is referred to in FlyBase by the symbol Dmel\Pex5 (CG14815, FBgn0023516). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:1866832..1869061. It has the cytological map location 2B13. Protein features are: Peroxisomal targeting signal 1 receptor family; Tetratricopeptide repeat; Tetratricopeptide repeat-containing domain; Tetratricopeptide-like helical domain. Its molecular function is described by: peroxisome matrix targeting signal-1 binding. It is involved in the biological process described with: protein import into peroxisome matrix, docking; response to anesthetic; peroxisome organization. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: chemical sensitive; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0039313	CG11892	-0.299336344	0.450941711	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11892 (FBgn0039313). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:25281548..25283237. It has the cytological map location 96C9. Protein features are: CHK kinase-like; Protein kinase-like domain; Protein of unknown function DUF227. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0039555	mRpS22	-0.29931667	0.385717808	0.999936032	MRPS22	MRPS22	high	NA	NA	NA	"The gene mitochondrial ribosomal protein S22 is referred to in FlyBase by the symbol Dmel\mRpS22 (CG12261, FBgn0039555). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:27916908..27918248. It has the cytological map location 98B6. Protein features are: Ribosomal protein S22, mitochondrial. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation. 3 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: lethal - all die during larval stage; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in adult female stages.  "
FBgn0029689	CG6428	-0.299243216	0.433290774	0.999936032	NA	ASPG	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6428 (FBgn0029689). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:3965435..3968655. It has the cytological map location 4A1. Protein features are: Ankyrin repeat; Ankyrin repeat-containing domain; Asparaginase/glutaminase, active site 1; Asparaginase/glutaminase, active site 2; Asparaginase/glutaminase-like; L-asparaginase, C-terminal domain; L-asparaginase, N-terminal; L-asparaginase, type I. Its molecular function is described by: asparaginase activity. It is involved in the biological process described with: asparagine catabolic process. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0033351	AIMP1	-0.29920657	0.394468762	0.999936032	NA	AIMP1	high	NA	NA	NA	"The gene aaRS-interacting multifunctional protein 1 is referred to in FlyBase by the symbol Dmel\AIMP1 (CG8235, FBgn0033351). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:8927014..8928105. It has the cytological map location 44F8. Protein features are: Nucleic acid-binding, OB-fold; tRNA-binding domain. Its molecular function is described by: tRNA binding. It is involved in the biological process described with: tRNA aminoacylation for protein translation. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed in adult female stages.  "
FBgn0051343	CG31343	-0.299125117	0.36804618	0.999936032	NA	ANPEP;TRHDE;LVRN;ENPEP;LNPEP;ERAP1;ERAP2;NPEPPS	moderate;low;low;low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31343 (FBgn0051343). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:21745266..21749003. It has the cytological map location 93F8. Protein features are: Aminopeptidase N-type; ERAP1-like C-terminal domain; Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase; Peptidase M1, membrane alanine aminopeptidase, N-terminal. Its molecular function is described by: zinc ion binding; metalloaminopeptidase activity; peptide binding. It is involved in the biological process described with: peptide catabolic process; proteolysis. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0037526	ArgRS-m	-0.299035211	0.454910733	0.999936032	NA	RARS2;RARS	high;low	NA	NA	NA	"The gene Arginyl-tRNA synthetase, mitochondrial is referred to in FlyBase by the symbol Dmel\ArgRS-m (CG10092, FBgn0037526). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:7887045..7890150. It has the cytological map location 84E4. Protein features are: Aminoacyl-tRNA synthetase, class I, conserved site; Aminoacyl-tRNA synthetase, class Ia, anticodon-binding; Arginine-tRNA ligase; Arginyl-tRNA synthetase, catalytic core domain; DALR anticodon binding; Rossmann-like alpha/beta/alpha sandwich fold. Its molecular function is described by: ATP binding; arginine-tRNA ligase activity. It is involved in the biological process described with: mitochondrial translation; arginyl-tRNA aminoacylation. 16 alleles are reported. The phenotypes of these alleles manifest in: eye; eye disc. The phenotypic class of alleles includes: visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0036886	CG9300	-0.29885288	0.423770517	0.999936032	NA	NOL11	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9300 (FBgn0036886). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:19552420..19554767. It has the cytological map location 76B7. Protein features are: NUC205; WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during pupal stage; lethal - all die before end of pupal stage; viable; lethal - all die during larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0261552	ps	-0.298809345	0.372935467	0.999936032	NA	NOVA2;NOVA1	high;high	NA	NA	NA	"The gene pasilla is referred to in FlyBase by the symbol Dmel\ps (CG42670, FBgn0261552). It is a protein_coding_gene from Drosophila melanogaster. It has 18 annotated transcripts and 18 polypeptides (12 unique). Gene sequence location is 3R:9417940..9455500. It has the cytological map location 85D16-85D17. Protein features are: K Homology domain; K Homology domain, type 1. Its molecular function is described by: mRNA binding. It is involved in the biological process described with: mRNA splicing, via spliceosome. 38 alleles are reported. The phenotypes of these alleles manifest in: germ band; presumptive embryonic salivary gland; wing; amnioserosa. The phenotypic classes of alleles include: lethal; visible; viable; sleep defective; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages.  "
FBgn0001974	l(2)35Bd	-0.298755789	0.45294771	0.999936032	NA	RNMT	high	NA	NA	NA	"The gene lethal (2) 35Bd is referred to in FlyBase by the symbol Dmel\l(2)35Bd (CG3688, FBgn0001974). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:15009939..15011764. It has the cytological map location 35B8. Protein features are: S-adenosyl-L-methionine-dependent methyltransferase; mRNA (guanine-N(7))-methyltransferase; mRNA (guanine-N(7))-methyltransferase domain. Its molecular function is described by: RNA binding; mRNA (guanine-N7-)-methyltransferase activity. It is involved in the biological process described with: RNA (guanine-N7)-methylation; 7-methylguanosine mRNA capping. 12 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: lethal; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0033557	CG12325	-0.298384357	0.454959478	0.999936032	NA	LOC102724159;PWP2	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12325 (FBgn0033557). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:10823405..10827644. It has the cytological map location 47C1. Protein features are: G-protein beta WD-40 repeat; Periodic tryptophan protein 2; Quinoprotein amine dehydrogenase, beta chain-like; Small-subunit processome, Utp12; WD40 repeat; WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: snoRNA binding. It is involved in the biological process described with: ribosomal small subunit assembly; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); cellular response to starvation. 4 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; ganglion mother cell; embryonic/larval neuroblast. The phenotypic classes of alleles include: lethal; lethal - all die during pupal stage; visible; viable; neuroanatomy defective; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0039241	CG11089	-0.298382622	0.404312439	0.999936032	NA	ATIC	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11089 (FBgn0039241). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:24877045..24881478. It has the cytological map location 96B2. Protein features are: AICAR transformylase domain; AICARFT/IMPCHase bienzyme; Cytidine deaminase-like; Methylglyoxal synthase-like domain. Its molecular function is described by: phosphoribosylaminoimidazolecarboxamide formyltransferase activity; IMP cyclohydrolase activity. It is involved in the biological process described with: wound healing; purine nucleotide biosynthetic process. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0064225	RpL5	-0.298247416	0.370042815	0.999936032	NA	RPL5	high	NA	NA	NA	"The gene Ribosomal protein L5 is referred to in FlyBase by the symbol Dmel\RpL5 (CG17489, FBgn0064225). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2L:22532279..22536884. It has the cytological map location 40F7. Protein features are: Ribosomal protein L5 eukaryotic/L18 archaeal; Ribosomal protein L5 eukaryotic/L18 archaeal, C-terminal. Its molecular function is described by: 5S rRNA binding; RNA binding; structural constituent of ribosome; protein binding. It is involved in the biological process described with: cytoplasmic translation; translation; ribosomal large subunit assembly. 8 alleles are reported. The phenotypes of these alleles manifest in: adult heart; macrochaeta; chaeta. The phenotypic classes of alleles include: developmental rate defective; phenotype; increased mortality during development; size defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.  "
FBgn0036760	CG5567	-0.298160616	0.383625877	0.999936032	PGP	PGP;PDXP	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5567 (FBgn0036760). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:17841540..17843544. It has the cytological map location 75A4. Protein features are: 2-phosphoglycolate phosphatase, eukaryotic; HAD-like domain; HAD-superfamily hydrolase, subfamily IIA. Its molecular function is described by: phosphoprotein phosphatase activity; alkaline phosphatase activity; phosphatase activity. It is involved in the biological process described with: protein dephosphorylation; dephosphorylation. 10 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0001330	kz	-0.298022201	0.444871285	0.999936032	DHX37	DHX37	high	NA	NA	NA	"The gene kurz is referred to in FlyBase by the symbol Dmel\kz (CG3228, FBgn0001330). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:2237858..2242035. It has the cytological map location 2F1. Protein features are: DEAD/DEAH box helicase domain; DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site; Domain of unknown function DUF1605; Helicase superfamily 1/2, ATP-binding domain; Helicase, C-terminal; Helicase-associated domain; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: RNA binding; helicase activity; ATP-dependent RNA helicase activity; ATP binding. It is involved in the biological process described with: RNA processing. 47 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; ganglion mother cell; embryonic/larval neuroblast; trichogen cell. The phenotypic classes of alleles include: lethal - all die before end of prepupal stage; cell lethal; phenotype; increased mortality during development; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0040763	CG18336	-0.297992111	0.33776964	0.999936032	NA	FAM166B;FAM166A	moderate;moderate	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG18336 (FBgn0040763). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:11293776..11294586. It has the cytological map location 47F1. Protein features are: Uncharacterised protein family UPF0573/UPF0605. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed in adult male stages.
FBgn0033196	CG1358	-0.29783709	0.402317532	0.999936032	NA	FLVCR2;FLVCR1;MFSD7	high;moderate;moderate	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG1358 (FBgn0033196). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2R:7595265..7620711. It has the cytological map location 43E3-43E5. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain. Its molecular function is unknown. It is involved in the biological process described with: transmembrane transport. 17 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: locomotor rhythm defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed during late pupal stages.
FBgn0022710	Ac13E	-0.297835591	0.464776879	0.999936032	ADCY9	ADCY9	high	NA	transmembrane protein	NA	"The gene Adenylyl cyclase 35C is referred to in FlyBase by the symbol Dmel\Ac13E (CG9210, FBgn0022710). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:15510877..15554278. It has the cytological map location 13C7-13D2. Protein features are: Adenylyl cyclase class-3/4/guanylyl cyclase; Adenylyl cyclase class-4/guanylyl cyclase, conserved site; Nucleotide cyclase. Its molecular function is described by: guanylate cyclase activity; adenylate cyclase activity. It is involved in the biological process described with: signal transduction; cGMP biosynthetic process; intracellular signal transduction; cAMP biosynthetic process. 6 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0035388	CG2162	-0.297614746	0.417701601	0.999936032	NA	R3HCC1L;R3HCC1	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG2162 (FBgn0035388). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3L:3035196..3040469. It has the cytological map location 63A3. Protein features are: R3H domain; RNA recognition motif domain. Its molecular function is described by: nucleic acid binding. The biological processes in which it is involved are not known. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; some die during pupal stage; viable; lethal - all die during P-stage; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 12-18 hour embryonic stages, in adult female stages.  "
FBgn0039829	CG15561	-0.297596339	0.469462528	0.999936032	NA	GPATCH4	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG15561 (FBgn0039829). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:31214776..31215942. It has the cytological map location 100B7. Protein features are: G-patch domain. Its molecular function is described by: nucleic acid binding. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 06-12 hour embryonic stages.
FBgn0035886	Jon66Ci	-0.297529686	0.282058082	0.999936032	NA	KLK3;C1S;PROC	low;low;low	NA	NA	NA	"The gene Jonah 66Ci is referred to in FlyBase by the symbol Dmel\Jon66Ci (CG7118, FBgn0035886). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:8391540..8392377. It has the cytological map location 66C10. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity; endopeptidase activity. It is involved in the biological process described with: proteolysis. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period.  "
FBgn0027549	CG7927	-0.297379397	0.390531009	0.999936032	NA	TCF25	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7927 (FBgn0027549). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:8110368..8113406. It has the cytological map location 66B6. Protein features are: Tetratricopeptide-like helical domain; Transcription factor 25. Its molecular function is described by: transcription factor activity, sequence-specific DNA binding. It is involved in the biological process described with: negative regulation of transcription from RNA polymerase II promoter. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 00-06 hour embryonic stages, in adult male stages.  "
FBgn0040899	CG17776	-0.297350177	0.416760401	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17776 (FBgn0040899). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:2184725..2185258. It has the cytological map location 2E1. Protein features are: Cytochrome c oxidase assembly protein COX14. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0038198	Npc2b	-0.297259933	0.42040255	0.999936032	NA	NPC2	moderate	NA	NA	NA	"The gene Niemann-Pick type C-2b is referred to in FlyBase by the symbol Dmel\Npc2b (CG3153, FBgn0038198). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:14089517..14092425. It has the cytological map location 88A8. Protein features are: Immunoglobulin E-set; MD-2-related lipid-recognition domain; ML domain, Npc2 like. Its molecular function is described by: sterol binding. It is involved in the biological process described with: intracellular cholesterol transport; multicellular organism reproduction; sterol transport; ecdysteroid biosynthetic process. 12 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: fertile; body color defective; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed at stages throughout the pupal period.  "
FBgn0053265	Muc68E	-0.297195463	0.384768992	0.999936032	NA	MUC17	high	NA	NA	NA	"The gene Mucin 68E is referred to in FlyBase by the symbol Dmel\Muc68E (CG33265, FBgn0053265). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:11967343..11972979. It has the cytological map location 68E4. Protein features are: Chitin binding domain. Its molecular function is described by: extracellular matrix structural constituent; chitin binding. It is involved in the biological process described with: chitin metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0030306	Spase25	-0.296725654	0.389421377	0.999936032	SPCS2	SPCS2	high	NA	transmembrane protein	NA	"The gene Spase 25-subunit is referred to in FlyBase by the symbol Dmel\Spase25 (CG1751, FBgn0030306). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is X:11485250..11486566. It has the cytological map location 10B15-10B16. Protein features are: Signal peptidase complex subunit 2. Its molecular function is described by: peptidase activity. It is involved in the biological process described with: signal peptide processing; protein targeting to ER. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period.  "
FBgn0038761	CG17190	-0.296638964	0.440252078	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG17190 (FBgn0038761). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:20011776..20013504. It has the cytological map location 92C1. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during early larval stages.
FBgn0026702	l(1)G0045	-0.29656353	0.467296215	0.999936032	NA	POP1	high	NA	NA	NA	"The gene lethal (1) G0045 is referred to in FlyBase by the symbol Dmel\l(1)G0045 (CG32763, FBgn0026702). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:5622648..5625493. It has the cytological map location 5A8. Protein features are: POPLD; Ribonuclease P/MRP, subunit POP1. Its molecular function is described by: ribonuclease P activity; ribonuclease MRP activity. It is involved in the biological process described with: tRNA processing; RNA phosphodiester bond hydrolysis, endonucleolytic; rRNA processing; tRNA 5'-leader removal. 8 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum. The phenotypic classes of alleles include: phenotype; increased mortality during development; lethal; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult female stages.  "
FBgn0039640	CG14516	-0.296370509	0.480730846	0.999936032	ANPEP	ANPEP;ENPEP;TRHDE;LVRN;LNPEP;ERAP1;ERAP2;NPEPPS	high;moderate;moderate;moderate;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14516 (FBgn0039640). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:29138662..29145787. It has the cytological map location 98F12. Protein features are: Aminopeptidase N-type; ERAP1-like C-terminal domain; Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase; Peptidase M1, membrane alanine aminopeptidase, N-terminal. Its molecular function is described by: metalloaminopeptidase activity; peptide binding; zinc ion binding. It is involved in the biological process described with: proteolysis; peptide catabolic process. 19 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0042083	CG3267	-0.296280948	0.420300695	0.999936032	MCCC2	MCCC2;PCCB	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3267 (FBgn0042083). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:6746381..6748954. It has the cytological map location 42C8. Protein features are: Acetyl-CoA carboxylase; Acetyl-coenzyme A carboxyltransferase, C-terminal; Acetyl-coenzyme A carboxyltransferase, N-terminal; ClpP/crotonase-like domain. Its molecular function is described by: methylcrotonoyl-CoA carboxylase activity. It is involved in the biological process described with: regulation of eclosion; leucine metabolic process. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal - majority die; viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0039858	CycG	-0.296157735	0.3757318	0.999936032	NA	CCNG1;CCNG2;CCNI2;CCNI	high;moderate;moderate;moderate	NA	NA	NA	"The gene Cyclin G is referred to in FlyBase by the symbol Dmel\CycG (CG11525, FBgn0039858). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is 3R:31596642..31612664. It has the cytological map location 100C7. Protein features are: Cyclin, N-terminal; Cyclin-like. Its molecular function is described by: cyclin-dependent protein serine/threonine kinase regulator activity. It is involved in the biological process described with: negative regulation of G1/S transition of mitotic cell cycle; regulation of Notch signaling pathway; female meiotic nuclear division; meiotic DNA repair synthesis; positive regulation of growth; double-strand break repair; epithelium development. 26 alleles are reported. The phenotypes of these alleles manifest in: dorsal appendage; abdominal tergite 6; karyosome; adult head; chorion; adult abdominal segment 5; cell component; ommatidium; female germline cell; posterior dorsal histoblast nest abdominal 6; somatic cell; adipose system. The phenotypic classes of alleles include: partially lethal; cell size defective; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0037121	Rpb8	-0.29609859	0.40510886	0.999936032	POLR2H	POLR2H	high	NA	NA	NA	"The gene Rpb8 is referred to in FlyBase by the symbol Dmel\Rpb8 (CG11246, FBgn0037121). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:21728932..21729694. It has the cytological map location 78E5. Protein features are: Nucleic acid-binding, OB-fold; RNA polymerase, Rpb8. Its molecular function is described by: RNA polymerase II activity; RNA polymerase III activity; RNA polymerase I activity. It is involved in the biological process described with: transcription from RNA polymerase II promoter; mitotic G2 DNA damage checkpoint. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; lethal - all die during larval stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0003274	RpLP2	-0.295805063	0.373918645	0.999936032	NA	RPLP2	high	NA	NA	NA	"The gene Ribosomal protein LP2 is referred to in FlyBase by the symbol Dmel\RpLP2 (CG4918, FBgn0003274). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:16586129..16586732. It has the cytological map location 53C9. Protein features are: Ribosomal protein L12 family. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: translational elongation; cytoplasmic translation. 11 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.  "
FBgn0039107	CG10300	-0.29574268	0.409485411	0.999936032	NA	TTPAL;CLVS1;RLBP1;CLVS2;TTPA	moderate;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10300 (FBgn0039107). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:23711527..23713313. It has the cytological map location 95A10. Protein features are: CRAL-TRIO lipid binding domain; CRAL/TRIO, N-terminal domain; Cellular retinaldehyde binding/alpha-tocopherol transport. Its molecular function is described by: transporter activity. It is involved in the biological process described with: transport. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0038638	CG7702	-0.295638064	0.39438037	0.999936032	NA	TPBGL;TPBG	low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7702 (FBgn0038638). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:18669390..18674679. It has the cytological map location 91B8-91C1. Protein features are: Leucine-rich repeat; Leucine-rich repeat domain, L domain-like; Leucine-rich repeat, typical subtype. Its molecular function is unknown. The biological processes in which it is involved are not known. 14 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 06-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0026252	msk	-0.295464806	0.385891988	0.999936032	NA	IPO7;IPO8	high;high	NA	transmembrane protein	NA	"The gene moleskin is referred to in FlyBase by the symbol Dmel\msk (CG7935, FBgn0026252). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:8116179..8121579. It has the cytological map location 66B6. Protein features are: Armadillo-like helical; Armadillo-type fold; Exportin/Importin, Cse1-like; Importin-beta, N-terminal domain. Its molecular function is described by: U1 snRNA binding; U2 snRNA binding; U4 snRNA binding; Ran GTPase binding; protein transporter activity; protein binding. It is involved in the biological process described with 19 unique terms, many of which group under: imaginal disc-derived appendage development; instar larval or pupal development; tube morphogenesis; post-embryonic animal morphogenesis; organic substance metabolic process; negative regulation of neuron apoptotic process; nucleic acid transport; cell proliferation; compound eye photoreceptor development; skeletal muscle organ development. 19 alleles are reported. The phenotypes of these alleles manifest in: muscle system; plasma membrane bounded cell projection; eye disc posterior to the morphogenetic furrow; cell part; trichogen cell; cell projection; developing material anatomical entity; rhabdomere; embryonic/larval imaginal precursor; chaeta; imaginal precursor; cell; visceral muscle. The phenotypic classes of alleles include: increased mortality; some die during P-stage; phenotype; cell death defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-06 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0003149	Prm	-0.295447963	0.399490968	0.999936032	NA	MYH4;MYH7;MYH13;MYH7B;MYH1;MYH3;MYH8;MYH15;MYH6;MYH2;MYO5B;MYH9;MYH10;MYH11;MYO5C;MYH14;MYO5A	moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;low;low;low;low;low;low;low	NA	NA	NA	"The gene Paramyosin is referred to in FlyBase by the symbol Dmel\Prm (CG5939, FBgn0003149). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is 3L:8732858..8745310. It has the cytological map location 66D12. Protein features are: Myosin tail. Its molecular function is described by: motor activity. It is involved in the biological process described with: myofibril assembly; mesoderm development. 19 alleles are reported. The phenotypes of these alleles manifest in: striated muscle myosin thick filament; trichogen cell; myofibril; somatic muscle; sarcomere. The phenotypic classes of alleles include: increased mortality; visible; increased mortality during development; phenotype; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0262560	wcd	-0.295004471	0.431446047	0.999936032	NA	UTP18	high	NA	NA	NA	"The gene wicked is referred to in FlyBase by the symbol Dmel\wcd (CG7989, FBgn0262560). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:16345838..16347500. It has the cytological map location 53C1. Protein features are: WD40 repeat; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: . It is involved in the biological process described with: female germ-line stem cell asymmetric division; rRNA processing; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); neuroblast proliferation. 11 alleles are reported. The phenotypes of these alleles manifest in: female germline stem cell; ganglion cell; mesothoracic tergum; neuroblast; embryonic/larval neuroblast; ganglion mother cell; trichogen cell. The phenotypic classes of alleles include: phenotype; increased mortality during development; increased mortality; partially lethal."
FBgn0039357	CG4743	-0.294770918	0.438155684	0.999936032	SLC25A26	SLC25A26	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4743 (FBgn0039357). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:25679242..25680550. It has the cytological map location 96E9. Protein features are: Mitochondrial carrier domain; Mitochondrial carrier protein; Mitochondrial substrate/solute carrier. Its molecular function is described by: S-adenosyl-L-methionine transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; mitochondrial transport; S-adenosyl-L-methionine transport. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: short lived; fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0034626	CG10795	-0.294724434	0.436830777	0.999936032	TM2D1	TM2D1	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG10795 (FBgn0034626). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:21383227..21384391. It has the cytological map location 57E1. Protein features are: TM2 domain. Its molecular function is described by: . It is involved in the biological process described with: . 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0037614	TMEM216	-0.294492954	0.429894633	0.999936032	NA	TMEM216;TMEM80	moderate;moderate	NA	transmembrane protein	NA	"The gene Transmembrane protein 216 is referred to in FlyBase by the symbol Dmel\TMEM216 (CG8116, FBgn0037614). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:8716243..8721320. It has the cytological map location 85A8-85A9. Protein features are: Uncharacterised protein family, transmembrane-17. Its molecular function is described by: . It is involved in the biological process described with: cilium assembly. 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; some die during pupal stage; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0038467	AdSL	-0.294412686	0.400954893	0.999936032	NA	ADSL	high	NA	NA	NA	"The gene Adenylosuccinate Lyase is referred to in FlyBase by the symbol Dmel\AdSL (CG3590, FBgn0038467). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:17018780..17021120. It has the cytological map location 89E8. Protein features are: Adenylosuccinate lyase; Adenylosuccinate lyase C-terminal; Fumarase/histidase, N-terminal; Fumarate lyase family; Fumarate lyase, N-terminal; Fumarate lyase, conserved site; L-Aspartase-like. Its molecular function is described by: N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity. It is involved in the biological process described with: 'de novo' AMP biosynthetic process; purine nucleotide metabolic process. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die during larval stage; viable; lethal - all die during P-stage; long lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0035144	Kah	-0.294349411	0.476195434	0.999936032	NA	SCRT1;SCRT2;SNAI3;SNAI1;SNAI2	moderate;moderate;low;low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene Kahuli is referred to in FlyBase by the symbol Dmel\Kah (CG17181, FBgn0035144). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:582824..589274. It has the cytological map location 61C5-61C6. Protein features are: Zinc finger C2H2-type. Its molecular function is described by: nucleic acid binding. The biological processes in which it is involved are not known. 10 alleles are reported. The phenotypes of these alleles manifest in: adult thorax; eye; adult cuticle; chaeta. The phenotypic classes of alleles include: fertile; visible; viable; flight defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 06-18 hour embryonic stages, during early pupal stages.  "
FBgn0032292	EMC3	-0.294276272	0.391032502	0.999936032	NA	EMC3	high	NA	transmembrane protein	NA	"The gene ER Membrane protein Complex 3 is referred to in FlyBase by the symbol Dmel\EMC3 (CG6750, FBgn0032292). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:10731400..10732423. It has the cytological map location 32A5. Protein features are: ER membrane protein complex subunit 3; Integral membrane protein EMC3/TMCO1-like. Its molecular function is described by: . It is involved in the biological process described with: rhabdomere development; protein folding in endoplasmic reticulum; wound healing; rhodopsin biosynthetic process. 6 alleles are reported. The phenotypes of these alleles manifest in: photoreceptor; rhabdomere microvillus; endoplasmic reticulum; Golgi apparatus; rhabdomere. The phenotypic classes of alleles include: lethal - all die before end of first instar larval stage; viable; lethal - all die before end of pupal stage; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0051102	CG31102	-0.294048087	0.392128608	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31102 (FBgn0051102). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:25293458..25295594. It has the cytological map location 96D1. Protein features are: CHK kinase-like; Protein kinase-like domain; Protein of unknown function DUF227. Its molecular function is unknown. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0033483	egr	-0.293750701	0.439494244	0.999936032	NA	EDA;TNFSF13;TNFSF12-TNFSF13;TNFSF13B	high;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene eiger is referred to in FlyBase by the symbol Dmel\egr (CG12919, FBgn0033483). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:10078366..10084210. It has the cytological map location 46E1-46E3. Protein features are: Tumour necrosis factor domain; Tumour necrosis factor, conserved site; Tumour necrosis factor-like domain. Its molecular function is described by: tumor necrosis factor receptor superfamily binding; receptor binding; tumor necrosis factor receptor binding; protein binding. It is involved in the biological process described with 14 unique terms, many of which group under: innate immune response; protein localization; asymmetric protein localization; apical protein localization; single-multicellular organism process; anatomical structure homeostasis; cellular component organization; nitrogen compound metabolic process; response to external biotic stimulus; response to stress; sensory perception; macromolecule localization. 36 alleles are reported. The phenotypes of these alleles manifest in: imaginal disc; embryo; hemolymph; embryonic/larval optic stalk; wing blade; sensory organ cell; wing disc; larval tagma; sensillum; epithelial cell; gastrula embryo. The phenotypic classes of alleles include: phenotype; increased mortality during development; viable; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages.  "
FBgn0035398	Cht7	-0.293634408	0.474090945	0.999936032	CHIT1	CHIA;CHIT1;OVGP1;CHI3L1;CHI3L2	high;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene Chitinase 7 is referred to in FlyBase by the symbol Dmel\Cht7 (CG1869, FBgn0035398). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:3090985..3106958. It has the cytological map location 63B1. Protein features are: Chitin binding domain; Chitinase II; Chitinase insertion domain; Glycoside hydrolase family 18, catalytic domain; Glycoside hydrolase superfamily; Glycoside hydrolase, chitinase active site. Its molecular function is described by: chitin binding; chitinase activity. It is involved in the biological process described with: chitin catabolic process; wound healing; carbohydrate metabolic process; chitin-based cuticle development; ecdysis, chitin-based cuticle. 8 alleles are reported. The phenotypes of these alleles manifest in: wing; embryonic/larval cuticle; pupal cuticle. The phenotypic classes of alleles include: eclosion defective; increased mortality during development; phenotype; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the pupal period.  "
FBgn0034967	eEF5	-0.293445474	0.378821038	0.999936032	NA	EIF5A2;EIF5A;EIF5AL1	high;high;moderate	NA	NA	NA	NA
FBgn0010100	Acon	-0.293291005	0.378992887	0.999936032	NA	ACO2	high	NA	NA	NA	"The gene Aconitase is referred to in FlyBase by the symbol Dmel\Acon (CG9244, FBgn0010100). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2L:21168570..21173185. It has the cytological map location 39A7. Protein features are: Aconitase A/isopropylmalate dehydratase small subunit, swivel domain; Aconitase family, 4Fe-4S cluster binding site; Aconitase, mitochondrial-like; Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain; Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3; Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2; Aconitase/3-isopropylmalate dehydratase, swivel. Its molecular function is described by: aconitate hydratase activity; 4 iron, 4 sulfur cluster binding. It is involved in the biological process described with: tricarboxylic acid cycle. 29 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval brain; mitochondrion. The phenotypic classes of alleles include: phenotype; increased mortality during development; lethal - all die before end of first instar larval stage; increased mortality; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0264672	Eogt	-0.293225313	0.467294039	0.999936032	NA	EOGT;POMGNT2	high;moderate	NA	NA	NA	"The gene EGF-domain O-GlcNAc transferase is referred to in FlyBase by the symbol Dmel\Eogt (CG9867, FBgn0264672). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:2381097..2383073. It has the cytological map location 22E1. Protein features are: Glycosyltransferase 61. Its molecular function is described by: protein N-acetylglucosaminyltransferase activity; protein O-GlcNAc transferase activity. It is involved in the biological process described with: metabolic process; larval chitin-based cuticle development; protein O-linked glycosylation; protein O-GlcNAcylation via threonine. 12 alleles are reported. The phenotypes of these alleles manifest in: epidermis; embryonic/larval tracheal system; wing blade posterior compartment; epithelium; wing; embryonic/larval dorsal trunk; embryonic/larval cuticle; adult thorax. The phenotypic classes of alleles include: some die during larval stage; lethal - all die during P-stage; increased mortality; fertile."
FBgn0032259	CG6144	-0.293086668	0.436808378	0.999936032	ALKBH6	ALKBH6	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6144 (FBgn0032259). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:10488694..10490461. It has the cytological map location 31F1. Protein features are: Alpha-ketoglutarate-dependent dioxygenase AlkB-like; Alpha-ketoglutarate-dependent dioxygenase alkB homologue 6; Oxoglutarate/iron-dependent dioxygenase. Its molecular function is described by: dioxygenase activity; ferrous iron binding. It is involved in the biological process described with: oxidation-reduction process. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal - all die during P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0031360	CG31937	-0.293053166	0.385970398	0.999936032	NA	DHRS7	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31937 (FBgn0031360). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:1729887..1731070. It has the cytological map location 22B1. Protein features are: NAD(P)-binding domain; Short-chain dehydrogenase/reductase SDR. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0259176	bun	-0.292968592	0.385021783	0.999936032	NA	TSC22D1;TSC22D2;TSC22D4;TSC22D3	high;moderate;moderate;moderate	DNA-binding with transcription factor activity(TSC22)	NA	NA	"The gene bunched is referred to in FlyBase by the symbol Dmel\bun (CG42281, FBgn0259176). It is a protein_coding_gene from Drosophila melanogaster. It has 10 annotated transcripts and 10 polypeptides (9 unique). Gene sequence location is 2L:12455540..12546611. It has the cytological map location 33E7-33E9. Protein features are: TSC-22 / Dip / Bun. Its molecular function is described by: transcription factor activity, sequence-specific DNA binding; protein homodimerization activity. It is involved in the biological process described with 22 unique terms, many of which group under: homeostatic process; instar larval or pupal development; negative regulation of programmed cell death; epithelium migration; brain development; decapentaplegic signaling pathway; sleep; regulation of transcription, DNA-templated; regulation of cell proliferation; homeostasis of number of cells; tissue regeneration; negative regulation of Notch signaling pathway; transcription, DNA-templated; post-embryonic animal morphogenesis. 168 alleles are reported. The phenotypes of these alleles manifest in: chorion; cell projection; dorsal appendage; dorsal thoracic disc; mechanosensory system; chorionic specialization; adult protocerebrum; cell part; embryonic segment; endocrine cell; germline cell; larval segment. The phenotypic classes of alleles include: developmental rate defective; lethal - all die before end of larval stage; phenotype; increased mortality during development; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0042138	CG18815	-0.292937707	0.384401795	0.999936032	NA	LYPLA1;LYPLA2;LYPLAL1	high;moderate;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG18815 (FBgn0042138). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is 3L:11628037..11630749. It has the cytological map location 68D1. Protein features are: Alpha/Beta hydrolase fold; Phospholipase/carboxylesterase/thioesterase. Its molecular function is described by: carboxylic ester hydrolase activity; palmitoyl-(protein) hydrolase activity. It is involved in the biological process described with: protein depalmitoylation. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0039467	CG14253	-0.292689813	0.445390989	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG14253 (FBgn0039467). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (2 unique). Gene sequence location is 3R:26978541..26985706. It has the cytological map location 97D12. Its molecular function is unknown. The biological processes in which it is involved are not known. 11 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages.
FBgn0040256	Ugt86Dd	-0.292586061	0.281622352	0.999936032	NA	UGT1A3;UGT1A1;UGT2A2;UGT2B10;UGT2A3;UGT2B15;UGT2B28;UGT2B17;UGT1A4;UGT1A10;UGT1A6;UGT1A8;UGT2B4;UGT2B11;UGT2B7;UGT1A7;UGT1A5;UGT1A9;UGT3A1;UGT8;UGT3A2	high;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene Ugt86Dd is referred to in FlyBase by the symbol Dmel\Ugt86Dd (CG6633, FBgn0040256). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:11126597..11128328. It has the cytological map location 86D4. Protein features are: UDP-glucuronosyl/UDP-glucosyltransferase; UDP-glycosyltransferase family, conserved site. Its molecular function is described by: glucuronosyltransferase activity. It is involved in the biological process described with: metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0086704	stops	-0.292525707	0.486418149	0.999936032	NA	ASB17	high	NA	NA	NA	"The gene slow termination of phototransduction is referred to in FlyBase by the symbol Dmel\stops (CG31006, FBgn0086704). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:31158156..31169106. It has the cytological map location 100B4-100B5. Protein features are: SOCS box domain. Its molecular function is unknown. It is involved in the biological process described with: deactivation of rhodopsin mediated signaling; sensory perception of sound; intracellular signal transduction. 20 alleles are reported. The phenotype of these alleles manifest in: eye photoreceptor cell. The phenotypic classes of alleles include: viable; neurophysiology defective; auditory perception defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 06-18 hour embryonic stages, during late pupal stages, in adult male stages.  "
FBgn0034537	DMAP1	-0.292437257	0.439395581	0.999936032	DMAP1	DMAP1	high	NA	NA	NA	"The gene DNA methyltransferase 1 associated protein 1 is referred to in FlyBase by the symbol Dmel\DMAP1 (CG11132, FBgn0034537). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:20644036..20645865. It has the cytological map location 57A9. Protein features are: DAMP1, SANT/Myb-like domain; DNA methyltransferase 1-associated 1; SWR1-complex protein 4/DNA methyltransferase 1-associated protein 1. Its molecular function is described by: transcription corepressor activity. It is involved in the biological process described with: DNA repair; positive regulation of innate immune response; negative regulation of transcription, DNA-templated; phagocytosis; histone H2A acetylation; chromatin remodeling; histone acetylation; positive regulation of antimicrobial peptide production; histone H4 acetylation. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; lethal - all die during P-stage; some die during larval stage; some die during pupal stage; lethal - all die before end of pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0038551	Odj	-0.292337956	0.430058905	0.999936032	NA	GFI1B;ZNF518B;ZNF8;ZNF560;ZNF281	low;low;low;low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene Oddjob is referred to in FlyBase by the symbol Dmel\Odj (CG7357, FBgn0038551). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:17807407..17809222. It has the cytological map location 90C6. Protein features are: Zinc finger C2H2-type; Zinc finger, AD-type. Its molecular function is described by: zinc ion binding; DNA binding. It is involved in the biological process described with: heterochromatin organization involved in chromatin silencing. 7 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum; wing. The phenotypic classes of alleles include: lethal; fertile; visible; viable; suppressor of variegation; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0036043	CG8177	-0.292094314	0.398417568	0.999936032	NA	SLC4A2;SLC4A3;SLC4A1;SLC4A10;SLC4A8;SLC4A7;SLC4A5;SLC4A4;SLC4A9;SLC4A11	high;moderate;moderate;moderate;moderate;moderate;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8177 (FBgn0036043). It is a protein_coding_gene from Drosophila melanogaster. It has 13 annotated transcripts and 13 polypeptides (8 unique). Gene sequence location is 3L:9763544..9786466. It has the cytological map location 67C7-67C8. Protein features are: Anion exchange protein; Band 3 cytoplasmic domain; Bicarbonate transporter, C-terminal; Bicarbonate transporter, eukaryotic; Phosphotransferase/anion transporter. Its molecular function is described by: sodium:bicarbonate symporter activity; inorganic anion exchanger activity. It is involved in the biological process described with: regulation of intracellular pH; anion transport. 17 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval midgut. The phenotypic classes of alleles include: lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0260004	Snmp1	-0.291928328	0.472440963	0.999936032	NA	SCARB2;SCARB1;CD36	moderate;moderate;low	NA	transmembrane protein	NA	"The gene Sensory neuron membrane protein 1 is referred to in FlyBase by the symbol Dmel\Snmp1 (CG7000, FBgn0260004). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:21165167..21168205. It has the cytological map location 93C2. Protein features are: CD36 family; CD36/scavenger receptor class B member 1. Its molecular function is unknown. It is involved in the biological process described with: response to pheromone; pupariation; detection of chemical stimulus involved in sensory perception of smell; cell surface receptor signaling pathway; lipid homeostasis; cellular response to pheromone. 50 alleles are reported. The phenotypes of these alleles manifest in: antennal intermediate sensillum I2; prothoracic gland; lipid particle; olfactory receptor neuron; adult olfactory receptor neuron Or67d. The phenotypic classes of alleles include: smell perception defective; neurophysiology defective; viable; lethal - all die before end of larval stage; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0029906	xit	-0.291893793	0.413294716	0.999936032	NA	ALG8	high	NA	transmembrane protein	NA	"The gene xiantuan is referred to in FlyBase by the symbol Dmel\xit (CG4542, FBgn0029906). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:6821016..6822840. It has the cytological map location 6D3. Protein features are: Glycosyl transferase, ALG6/ALG8. Its molecular function is described by: dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity; dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity. It is involved in the biological process described with: oligosaccharide-lipid intermediate biosynthetic process; protein N-linked glycosylation; germ-band extension; apical constriction involved in gastrulation; protein glycosylation. 8 alleles are reported. The phenotypes of these alleles manifest in: ventral furrow; cephalic furrow. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0015011	AhcyL2	-0.291834074	0.405123204	0.999936032	NA	AHCYL2;AHCYL1;AHCY	moderate;moderate;low	NA	NA	NA	"The gene Adenosylhomocysteinase like 2 is referred to in FlyBase by the symbol Dmel\AhcyL2 (CG8956, FBgn0015011). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:16978439..16982158. It has the cytological map location 89E5. Protein features are: Adenosylhomocysteinase-like; NAD(P)-binding domain; S-adenosyl-L-homocysteine hydrolase, NAD binding domain; S-adenosyl-L-homocysteine hydrolase, conserved site. Its molecular function is described by: adenosylhomocysteinase activity. It is involved in the biological process described with: one-carbon metabolic process; S-adenosylmethionine cycle. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: long lived; viable; aging defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during late larval stages, at stages throughout the pupal period.  "
FBgn0026160	tna	-0.291412359	0.422235905	0.999936032	NA	ZMIZ1;ZMIZ2;PIAS3;PIAS4;PIAS1;PIAS2	high;high;low;low;low;low	DNA-binding with transcription factor activity(zf-MIZ)	NA	NA	"The gene tonalli is referred to in FlyBase by the symbol Dmel\tna (CG7958, FBgn0026160). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3L:10857889..10876496. It has the cytological map location 67F1. Protein features are: WD40/YVTN repeat-like-containing domain; Zinc finger, MIZ-type. Its molecular function is described by: zinc ion binding. It is involved in the biological process described with: chromatin-mediated maintenance of transcription. 19 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; wing. The phenotypic classes of alleles include: viable; visible; lethal - all die before end of larval stage; lethal; lethal - all die before end of P-stage; some die during pharate adult stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, in adult male stages.  "
FBgn0037195	CG11226	-0.291039031	0.461253965	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11226 (FBgn0037195). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:22837068..22838170. It has the cytological map location 80A4. Its molecular function is unknown. The biological processes in which it is involved are not known. 8 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval hemocyte. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0001994	crp	-0.290728057	0.427798813	0.999936032	NA	TFAP4	high	DNA-binding with transcription factor activity(HLH)	NA	NA	"The gene cropped is referred to in FlyBase by the symbol Dmel\crp (CG7664, FBgn0001994). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:16263556..16287730. It has the cytological map location 35F1. Protein features are: Myc-type, basic helix-loop-helix (bHLH) domain. Its molecular function is described by: sequence-specific DNA binding; myosin binding; protein dimerization activity; transcription factor activity, sequence-specific DNA binding. It is involved in the biological process described with: larval somatic muscle development; regulation of transcription from RNA polymerase II promoter. 86 alleles are reported. The phenotypes of these alleles manifest in: immaterial anatomical entity; tracheal tip cell; embryonic/larval salivary gland; early extended germ band embryo; syncytium; adipose system; tracheal lumen; tergum; anatomical space; abdomen; embryonic/larval digestive system. The phenotypic classes of alleles include: cell size defective; increased mortality during development; phenotype; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0036980	RhoBTB	-0.290520961	0.427812502	0.999936032	NA	RHOBTB2;RHOBTB1	high;high	NA	transmembrane protein	NA	"The gene Rho-related BTB domain containing is referred to in FlyBase by the symbol Dmel\RhoBTB (CG5701, FBgn0036980). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3L:20376242..20382398. It has the cytological map location 77B6-77B9. Protein features are: BTB/POZ domain; P-loop containing nucleoside triphosphate hydrolase; SKP1/BTB/POZ domain; Small GTP-binding protein domain; Small GTPase superfamily; Small GTPase superfamily, Rho type. Its molecular function is described by: GTP binding; GTPase activity. It is involved in the biological process described with: melanotic encapsulation of foreign target; small GTPase mediated signal transduction. 12 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: immune response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0037838	CG4089	-0.290215145	0.489743255	0.999936032	NA	TTLL1;TTLL5;TTLL4	low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4089 (FBgn0037838). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:10815288..10817490. It has the cytological map location 86C7. Protein features are: Tubulin-tyrosine ligase/Tubulin polyglutamylase. Its molecular function is unknown. It is involved in the biological process described with: cellular protein modification process. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages, during early larval stages, during late pupal stages.  "
FBgn0266430	CG45060	-0.290212941	0.476458973	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG45060 (FBgn0266430). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:9868068..9868568. It has the cytological map location 9A2. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable.
FBgn0038947	Sar1	-0.289977628	0.386756754	0.999936032	NA	SAR1B;SAR1A	high;moderate	NA	NA	NA	"The gene Secretion-associated Ras-related 1 is referred to in FlyBase by the symbol Dmel\Sar1 (CG7073, FBgn0038947). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 3R:22356685..22360711. It has the cytological map location 94A5-94A6. Protein features are: P-loop containing nucleoside triphosphate hydrolase; Small GTP-binding protein domain; Small GTPase superfamily, ARF/SAR type; Small GTPase superfamily, SAR1-type. Its molecular function is described by: GTP binding; scaffold protein binding; GTPase activity. It is involved in the biological process described with 12 unique terms, many of which group under: cellular process; cellular component organization or biogenesis; cuticle development involved in chitin-based cuticle molting cycle; regulation of protein localization; animal organ development; secretion; cell morphogenesis involved in differentiation; chitin-based cuticle development; single-organism localization; protein exit from endoplasmic reticulum; regulation of cellular component biogenesis; protein secretion; dendrite morphogenesis. 14 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval epidermis; embryonic/first instar larval cuticle; embryonic/larval trachea; endoplasmic reticulum; Z disc; embryonic pericardial cell; cardioblast; sarcomere. The phenotypic classes of alleles include: some die during larval stage; lethal - all die before end of larval stage; increased mortality; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0053993	CG33993	-0.289939195	0.417802371	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG33993 (FBgn0053993). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:5933036..5950658. It has the cytological map location 65A1. Protein features are: SH2 domain. Its molecular function is described by: . It is involved in the biological process described with: . 7 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: visible; viable; flightless. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 06-18 hour embryonic stages, during early pupal stages.  "
FBgn0026313	X11L	-0.289888438	0.465136068	0.999936032	NA	APBA1;APBA2;APBA3	moderate;moderate;moderate	NA	NA	NA	"The gene X11L is referred to in FlyBase by the symbol Dmel\X11L (CG5675, FBgn0026313). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is X:17599608..17606879. It has the cytological map location 16B7. Protein features are: PDZ domain; PH domain-like; PTB/PI domain. Its molecular function is described by: cell adhesion molecule binding. It is involved in the biological process described with: neurotransmitter secretion; synaptic vesicle targeting; compound eye development; synaptic vesicle docking; protein localization to membrane; establishment or maintenance of cell polarity. 20 alleles are reported. The phenotypes of these alleles manifest in: cell projection; mushroom body medial lobe; interommatidial bristle; plasma membrane bounded cell projection; peripheral nervous system; cell part; mushroom body vertical lobe; rhabdomere; cell; cell. The phenotypic classes of alleles include: increased cell death; fertile; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 12-18 hour embryonic stages, during early pupal stages, in adult female stages.  "
FBgn0039175	beta-PheRS	-0.289725837	0.415077352	0.999936032	NA	FARSB	high	NA	NA	NA	"The gene Phenylalanyl-tRNA synthetase, ‘_-subunit is referred to in FlyBase by the symbol Dmel\‘_-PheRS (CG5706, FBgn0039175). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:24250460..24252679. It has the cytological map location 95F5-95F6. Protein features are: B3/B4 tRNA-binding domain; Phenylalanyl-tRNA synthetase, B3/B4; Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic; Putative DNA-binding domain; tRNA synthetase, B5-domain. Its molecular function is described by: RNA binding; phenylalanine-tRNA ligase activity; ATP binding; magnesium ion binding; aminoacyl-tRNA editing activity. It is involved in the biological process described with: phenylalanyl-tRNA aminoacylation. 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die during embryonic stage; partially lethal; lethal - all die during larval stage; short lived; lethal; female sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0038438	Der-2	-0.289290903	0.398267067	0.999936032	DERL2	DERL2;DERL3;DERL1	high;moderate;low	NA	transmembrane protein	NA	"The gene Derlin-2 is referred to in FlyBase by the symbol Dmel\Der-2 (CG14899, FBgn0038438). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:16482694..16484223. It has the cytological map location 89B18. Protein features are: Derlin; Peptidase S54, rhomboid domain. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: ubiquitin-dependent ERAD pathway; defense response to bacterium; endoplasmic reticulum unfolded protein response. 9 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0033376	CG8777	-0.289229705	0.477747755	0.999936032	TTC37	TTC37	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8777 (FBgn0033376). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:9098539..9103153. It has the cytological map location 45A3-45A4. Protein features are: Tetratricopeptide repeat; Tetratricopeptide repeat-containing domain; Tetratricopeptide-like helical domain. Its molecular function is unknown. It is involved in the biological process described with: nuclear-transcribed mRNA catabolic process. 5 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0034727	mRpS29	-0.289228196	0.409545585	0.999936032	NA	DAP3	high	NA	NA	NA	"The gene mitochondrial ribosomal protein S29 is referred to in FlyBase by the symbol Dmel\mRpS29 (CG3633, FBgn0034727). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:22418937..22420376. It has the cytological map location 58E1. Protein features are: P-loop containing nucleoside triphosphate hydrolase; Ribosomal protein S23/S29, mitochondrial; Ribosomal protein S29, mitochondrial. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: apoptotic process; translation; mitochondrial translation. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal; lethal - all die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, during early larval stages.  "
FBgn0036342	CG11279	-0.289076984	0.411068151	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11279 (FBgn0036342). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3L:13046977..13048919. It has the cytological map location 69F6. Protein features are: Uncharacterised protein family UPF0390. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0019957	ND-42	-0.288882802	0.388205334	0.999936032	NA	NDUFA10	high	NA	NA	NA	"The gene NADH dehydrogenase (ubiquinone) 42 kDa subunit is referred to in FlyBase by the symbol Dmel\ND-42 (CG6343, FBgn0019957). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:22027709..22029393. It has the cytological map location 94A1. Protein features are: Deoxynucleoside kinase domain; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: NADH dehydrogenase activity; NADH dehydrogenase (ubiquinone) activity. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone; regulation of glucose metabolic process. 14 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; eye photoreceptor cell; mesothoracic tergum; rhabdomere; retinal pigment cell. The phenotypic classes of alleles include: viable; visible; body color defective; lethal - all die during larval stage; lethal; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0029992	Upf2	-0.288796032	0.490752888	0.999936032	UPF2	UPF2	high	NA	NA	NA	"The gene Upf2 is referred to in FlyBase by the symbol Dmel\Upf2 (CG2253, FBgn0029992). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:8070244..8075466. It has the cytological map location 7D5. Protein features are: Armadillo-type fold; MIF4G-like, type 3; Up-frameshift suppressor 2. Its molecular function is described by: RNA binding. It is involved in the biological process described with: nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; neuromuscular synaptic transmission; synapse organization. 23 alleles are reported. The phenotypes of these alleles manifest in: adult tracheal system; follicle cell; eye; dorsal appendage. The phenotypic classes of alleles include: phenotype; fertile; increased mortality; some die during larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0035131	mthl9	-0.288323162	0.47281636	0.999936032	NA	ADGRF3	high	NA	transmembrane protein	GPCR	"The gene methuselah-like 9 is referred to in FlyBase by the symbol Dmel\mthl9 (CG17084, FBgn0035131). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:329822..332309. It has the cytological map location 61C1. Protein features are: Methuselah ectodomain, domain 2; Methuselah, N-terminal domain. Its molecular function is described by: G-protein coupled receptor activity. It is involved in the biological process described with: G-protein coupled receptor signaling pathway; response to starvation; determination of adult lifespan. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: flightless; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages.  "
FBgn0040252	Ugt86Dh	-0.288278855	0.396046864	0.999936032	NA	UGT1A3;UGT2B10;UGT1A1;UGT2B4;UGT2B15;UGT2B28;UGT2A2;UGT2B17;UGT2B11;UGT2A3;UGT2B7;UGT3A1;UGT8;UGT3A2;UGT1A4;UGT1A10;UGT1A7;UGT1A5;UGT1A9;UGT1A6;UGT1A8	moderate;moderate;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene Ugt86Dh is referred to in FlyBase by the symbol Dmel\Ugt86Dh (CG4772, FBgn0040252). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:11175529..11177910. It has the cytological map location 86D6. Protein features are: UDP-glucuronosyl/UDP-glucosyltransferase; UDP-glycosyltransferase family, conserved site. Its molecular function is described by: glucuronosyltransferase activity. It is involved in the biological process described with: metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: pain response defective; partially lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0032499	Uvrag	-0.288263973	0.442806801	0.999936032	NA	UVRAG	high	NA	NA	NA	"The gene UV-resistance associated gene is referred to in FlyBase by the symbol Dmel\Uvrag (CG6116, FBgn0032499). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:13286777..13289556. It has the cytological map location 34B4. Protein features are: UV radiation resistance protein/autophagy-related protein 14. Its molecular function is described by: SNARE binding. It is involved in the biological process described with: negative regulation of Notch signaling pathway; positive regulation of receptor-mediated endocytosis; imaginal disc-derived male genitalia morphogenesis; neuron remodeling; negative regulation of cell proliferation; positive regulation of autophagy; SNARE complex assembly. 11 alleles are reported. The phenotypes of these alleles manifest in: male genitalia; follicle cell; autolysosome; gamma Kenyon cell; eye; major mitochondrial derivative; embryonic/larval fat body. The phenotypic classes of alleles include: phenotype; increased mortality during development; lethal; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0032845	CG10747	-0.288263973	0.442806801	0.999936032	PLCXD2	PLCXD2;PLCXD3;PLCXD1	high;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10747 (FBgn0032845). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:20089636..20091348. It has the cytological map location 38B5. Protein features are: PLC-like phosphodiesterase, TIM beta/alpha-barrel domain; Phosphatidylinositol-specific phospholipase C, X domain. Its molecular function is described by: phosphoric diester hydrolase activity. It is involved in the biological process described with: lipid metabolic process. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0052267	CG32267	-0.288247087	0.409366379	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32267 (FBgn0052267). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:3471555..3472113. It has the cytological map location 63E2. Its molecular function is described by: . It is involved in the biological process described with: . 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0029848	Btnd	-0.288074817	0.301723852	0.999936032	NA	BTD;VNN2;VNN1;VNN3	moderate;high;moderate;moderate	NA	NA	NA	"The gene Biotinidase is referred to in FlyBase by the symbol Dmel\Btnd (CG3599, FBgn0029848). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:6217268..6219327. It has the cytological map location 5E1. Protein features are: Biotinidase-like, eukaryotic; Carbon-nitrogen hydrolase. Its molecular function is described by: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds. It is involved in the biological process described with: peptidyl-lysine biotinylation; response to heat; histone biotinylation. 6 alleles are reported. The phenotypes of these alleles manifest in: sarcomere; myofibril; M band. The phenotypic classes of alleles include: partially lethal - majority die; increased mortality; increased mortality during development; phenotype; flight defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during early larval stages.  "
FBgn0010406	RNaseX25	-0.288005314	0.419047487	0.999936032	RNASET2	RNASET2	high	NA	NA	NA	"The gene Ribonuclease X25 is referred to in FlyBase by the symbol Dmel\RNaseX25 (CG8194, FBgn0010406). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:7970588..7972449. It has the cytological map location 66A21. Protein features are: Ribonuclease T2, His active site 2; Ribonuclease T2, eukaryotic; Ribonuclease T2-like. Its molecular function is described by: ribonuclease T2 activity; RNA binding; ribonuclease activity. It is involved in the biological process described with: RNA catabolic process; multicellular organism reproduction. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  CAVEAT: These RNA-Seq temporal profiles depend upon RNA-Seq reads that are uniquely placed in the genome.  For this reason, genes such as histones, Stellates and many classes of RNA genes that are present in multiple exact or near exact copies in the genome, expression levels may be reported as much lower than their true values."
FBgn0037898	CG18643	-0.287957723	0.466885767	0.999936032	DTD1	DTD1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG18643 (FBgn0037898). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:11430061..11430762. It has the cytological map location 86E5. Protein features are: D-Tyr tRNAtyr deacylase-like domain; D-aminoacyl-tRNA deacylase DTD. Its molecular function is described by: D-tyrosyl-tRNA(Tyr) deacylase activity; aminoacyl-tRNA editing activity. It is involved in the biological process described with: tRNA metabolic process. 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult female stages.  "
FBgn0037057	CG10512	-0.287951662	0.416176401	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10512 (FBgn0037057). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 3L:21202920..21208092. It has the cytological map location 78C2. Protein features are: Malate/L-lactate dehydrogenase-like. Its molecular function is described by: oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. 9 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 06-12 and 18-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0027554	CG8042	-0.287745413	0.438598506	0.999936032	NA	UBXN4;UBXN1	high;low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG8042 (FBgn0027554). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:7972449..7974991. It has the cytological map location 66A21. Protein features are: Thioredoxin-like fold; UBX domain; Ubiquitin-related domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed in adult male stages.
FBgn0030693	CG8974	-0.287577098	0.392294518	0.999936032	RNF185	RNF185;RNF5	moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8974 (FBgn0030693). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is X:15793721..15796028. It has the cytological map location 13E18-13F1. Protein features are: Zinc finger, RING-type; Zinc finger, RING-type, conserved site; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: zinc ion binding; ubiquitin protein ligase activity involved in ERAD pathway; ubiquitin-like protein conjugating enzyme binding; ubiquitin-protein transferase activity. It is involved in the biological process described with: ER-associated misfolded protein catabolic process; protein ubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0038865	cDIP	-0.287315025	0.476851092	0.999936032	NA	LRRC6;LRRC17;LRRC15;GP5;CPN2	low;low;low;low;low	NA	NA	NA	"The gene Common Dpr-interacting protein is referred to in FlyBase by the symbol Dmel\cDIP (CG10824, FBgn0038865). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:21159238..21161092. It has the cytological map location 93C2. Protein features are: Leucine-rich repeat; Leucine-rich repeat domain, L domain-like; Leucine-rich repeat, typical subtype. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. The phenotypic classes of allele include: some die during pupal stage; partially lethal - majority die; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed during early larval stages, in stages of adults of both sexes.  "
FBgn0038746	Surf6	-0.287175236	0.457736054	0.999936032	NA	SURF6	high	NA	NA	NA	"The gene Surfeit 6 is referred to in FlyBase by the symbol Dmel\Surf6 (CG4510, FBgn0038746). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:19903665..19904868. It has the cytological map location 92B6. Protein features are: Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain; Surfeit locus 6. Its molecular function is described by: RNA binding; DNA binding; nucleic acid binding. It is involved in the biological process described with: ribosome biogenesis; ribosomal small subunit biogenesis; ventral cord development; ribosomal large subunit biogenesis. 6 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval neuroblast; ganglion mother cell; apterous-expressing neuron of the lateral cluster of the thorax Ap4; apterous-expressing neuron of the lateral cluster of the thorax; trichogen cell. The phenotypic classes of alleles include: neuroanatomy defective; viable; lethal - all die during P-stage; visible; fertile; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, in adult female stages.  "
FBgn0036111	Aps	-0.287041593	0.404079302	0.999936032	NA	NUDT3;NUDT11;NUDT10;NUDT4	high;moderate;moderate;moderate	NA	NA	NA	"The gene Aps is referred to in FlyBase by the symbol Dmel\Aps (CG6391, FBgn0036111). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3L:10894776..10899123. It has the cytological map location 67F1. Protein features are: NUDIX hydrolase domain; NUDIX hydrolase domain-like; NUDIX hydrolase, conserved site. Its molecular function is described by: bis(5'-adenosyl)-hexaphosphatase activity; m7G(5')pppN diphosphatase activity; endopolyphosphatase activity; bis(5'-adenosyl)-pentaphosphatase activity; diphosphoinositol-polyphosphate diphosphatase activity. It is involved in the biological process described with: glucose homeostasis; adenosine 5'-(hexahydrogen pentaphosphate) catabolic process; inositol phosphate metabolic process; regulation of insulin receptor signaling pathway; response to starvation; diphosphoinositol polyphosphate metabolic process; lipid homeostasis; nucleotide metabolic process; diadenosine hexaphosphate catabolic process; diadenosine pentaphosphate catabolic process. 11 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; starvation stress response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0034243	Ns2	-0.286982022	0.418566029	0.999936032	NA	GNL2	high	NA	NA	NA	"The gene Nucleostemin 2 is referred to in FlyBase by the symbol Dmel\Ns2 (CG6501, FBgn0034243). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:17565779..17568456. It has the cytological map location 54C8-54C9. Protein features are: Circularly permuted (CP)-type guanine nucleotide-binding (G) domain; GTP binding domain; GTP-binding protein, orthogonal bundle domain; Nucleolar GTP-binding protein 2; Nucleolar GTP-binding protein 2, N-terminal domain; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: GTP binding; GTPase activity. It is involved in the biological process described with: phagocytosis; ribosome biogenesis; compound eye morphogenesis; positive regulation of multicellular organism growth. 13 alleles are reported. The phenotypes of these alleles manifest in: eye; wing disc. The phenotypic classes of alleles include: long lived; small body; lethal - all die before end of first instar larval stage; visible; some die during first instar larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages.  "
FBgn0267450	CR45800	-0.286373208	0.339857829	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45800 (FBgn0267450). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3R:20325529..20326260. It has the cytological map location 92E2-92E3. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0263256	CG43394	-0.286279872	0.458317014	0.999936032	NA	MANSC4;MANSC1;C11orf24	low;low;low	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG43394 (FBgn0263256). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is 2L:8145758..8158786. It has the cytological map location 28E8-28E9. Protein features are: Immunoglobulin-like fold. Its molecular function is described by: . It is involved in the biological process described with: . 11 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable.
FBgn0023169	AMPKalpha	-0.286279376	0.406567043	0.999936032	NA	PRKAA2;PRKAA1	high;moderate	NA	NA	GPCR	"The gene AMP-activated protein kinase ‘± subunit is referred to in FlyBase by the symbol Dmel\AMPK‘± (CG3051, FBgn0023169). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is X:1375536..1378896. It has the cytological map location 2A1. Protein features are: AMPK, C-terminal adenylate sensor domain; KA1 domain/Ssp2, C-terminal; Protein kinase domain; Protein kinase, ATP binding site; Protein kinase-like domain; Serine/threonine-protein kinase, active site. Its molecular function is described by: ATP binding; protein serine/threonine kinase activity; AMP-activated protein kinase activity; G-protein coupled receptor kinase activity; histone serine kinase activity. It is involved in the biological process described with 18 unique terms, many of which group under: vesicle-mediated transport; protein modification process; mitotic cell cycle; lipid metabolic process; regulation of cellular carbohydrate metabolic process; localization; phagocytosis; system process; glucose metabolic process; cell cycle; macromolecule localization; regulation of signaling; regulation of cell size; cellular macromolecule metabolic process; response to abiotic stimulus. 34 alleles are reported. The phenotypes of these alleles manifest in: somatic precursor cell; trichome field; fat body; presumptive embryonic/larval integumentary system; cell periphery; dendrite; somatic stem cell; circular visceral muscle fiber; embryonic/larval adipose system; alimentary canal. The phenotypic classes of alleles include: behavior defective; cell cycle defective; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, in stages of adults of both sexes.  "
FBgn0037608	mRpL19	-0.286253827	0.419996829	0.999936032	MRPL19	MRPL19	high	NA	NA	NA	"The gene mitochondrial ribosomal protein L19 is referred to in FlyBase by the symbol Dmel\mRpL19 (CG8039, FBgn0037608). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:8674109..8675196. It has the cytological map location 85A5. Protein features are: Ribosomal protein L19; Translation protein SH3-like domain. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation. 4 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: lethal; viable; visible; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed during early larval stages.  "
FBgn0039109	CG10365	-0.286129296	0.419522944	0.999936032	NA	CHAC1;CHAC2	high;moderate	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG10365 (FBgn0039109). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 3R:23723331..23731499. It has the cytological map location 95B1. Protein features are: Gamma-glutamyl cyclotransferase-like; Glutathione-specific gamma-glutamylcyclotransferase. Its molecular function is described by: Notch binding; gamma-glutamylcyclotransferase activity. It is involved in the biological process described with: neurogenesis; glutathione catabolic process. 11 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed during early pupal stages.
FBgn0037472	CG10098	-0.286043384	0.463015583	0.999936032	SCRN3	SCRN3;SCRN2;SCRN1	high;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10098 (FBgn0037472). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:7124548..7126503. It has the cytological map location 84C3-84C4. Protein features are: Peptidase C69, dipeptidase A. Its molecular function is described by: dipeptidase activity. It is involved in the biological process described with: exocytosis; proteolysis. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: pain response defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, during early pupal stages.  "
FBgn0050414	CG30414	-0.285966957	0.493424837	0.999936032	NA	HABP2;GZMK;PLAT;TMPRSS4	low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG30414 (FBgn0050414). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:23384200..23385468. It has the cytological map location 59D9. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed during late larval stages.  "
FBgn0030789	Rrp45	-0.285746393	0.466837241	0.999936032	NA	EXOSC9	high	NA	NA	NA	"The gene Rrp45 is referred to in FlyBase by the symbol Dmel\Rrp45 (CG9606, FBgn0030789). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:16789405..16791266. It has the cytological map location 15A8. Protein features are: Exoribonuclease, phosphorolytic domain 1; Exoribonuclease, phosphorolytic domain 2; Exosome complex component RRP45; PNPase/RNase PH domain; Ribosomal protein S5 domain 2-type fold. Its molecular function is described by: AU-rich element binding. It is involved in the biological process described with: nuclear polyadenylation-dependent rRNA catabolic process; nuclear polyadenylation-dependent tRNA catabolic process; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'; U5 snRNA 3'-end processing; U4 snRNA 3'-end processing; exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; U1 snRNA 3'-end processing; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); nuclear polyadenylation-dependent mRNA catabolic process; nuclear mRNA surveillance. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0031732	CG11149	-0.285727684	0.398792458	0.999936032	NA	B4GAT1	moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11149 (FBgn0031732). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (2 unique). Gene sequence location is 2L:5718121..5720899. It has the cytological map location 25F3. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during late larval stages, in stages of adults of both sexes.  "
FBgn0266064	GlyS	-0.285601894	0.440486815	0.999936032	NA	GYS1;GYS2	high;moderate	NA	NA	NA	"The gene Glycogen synthase is referred to in FlyBase by the symbol Dmel\GlyS (CG6904, FBgn0266064). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3R:15141843..15147531. It has the cytological map location 88E2. Protein features are: Glycogen synthase. Its molecular function is described by: glycogen (starch) synthase activity. It is involved in the biological process described with: cellular response to starvation; glycophagy; positive regulation of glycogen catabolic process; glycogen biosynthetic process; cellular response to sucrose stimulus; response to sucrose; glycogen metabolic process. 13 alleles are reported. The phenotypes of these alleles manifest in: glycogen granule; neuron; autophagosome. The phenotypic classes of alleles include: neuroanatomy defective; gravitaxis defective; starvation stress response defective; increased mortality; phenotype."
FBgn0029791	CG4096	-0.285511274	0.285725046	0.999936032	ADAMTS7	ADAMTS7;ADAMTS12;ADAMTS6;ADAMTS17;ADAMTS10;ADAMTS18;ADAMTS19;ADAMTS16;ADAMTS13;THSD4;ADAMTSL4;PAPLN;ADAMTSL5;ADAMTS1;ADAMTS14	high;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;low;low;low;moderate;low;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4096 (FBgn0029791). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:5698557..5708633. It has the cytological map location 5B1. Protein features are: ADAM, cysteine-rich; ADAM-TS Spacer 1; Metallopeptidase, catalytic domain; Peptidase M12B, ADAM-TS; Peptidase M12B, ADAM/reprolysin; Peptidase M12B, propeptide; Thrombospondin type-1 (TSP1) repeat. Its molecular function is described by: zinc ion binding; metalloendopeptidase activity. It is involved in the biological process described with: proteolysis; negative regulation of epidermal growth factor receptor signaling pathway. 4 alleles are reported. The phenotypes of these alleles manifest in: wing vein; wing. The phenotypic classes of alleles include: visible; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 06-12 hour embryonic stages, during early pupal stages.  "
FBgn0029999	CG1575	-0.285409849	0.43733161	0.999936032	NA	TEX10	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1575 (FBgn0029999). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:8117012..8119130. It has the cytological map location 7D6. Protein features are: Armadillo-like helical; Armadillo-type fold; Pre-rRNA-processing protein IPI1/Testis-expressed sequence 10 protein. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. The phenotypes of this allele manifest in: embryonic/larval somatic muscle; Z disc; trichogen cell; sarcomere; mesothoracic tergum. The phenotypic classes of allele include: lethal - all die during larval stage; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0031321	Tgt	-0.285283367	0.424738978	0.999936032	QTRT1	QTRT1	high	NA	NA	NA	"The gene tRNA-guanine transglycosylase is referred to in FlyBase by the symbol Dmel\Tgt (CG4947, FBgn0031321). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:1184065..1185698. It has the cytological map location 21F2. Protein features are: tRNA-guanine transglycosylase; tRNA-guanine(15) transglycosylase-like. Its molecular function is described by: queuine tRNA-ribosyltransferase activity. It is involved in the biological process described with: tRNA-guanine transglycosylation; queuosine biosynthetic process. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0028646	aralar1	-0.285205908	0.408534341	0.999936032	NA	SLC25A12;SLC25A13;SLC25A18;SLC25A22	high;moderate;low;low	NA	transmembrane protein	NA	"The gene aralar1 is referred to in FlyBase by the symbol Dmel\aralar1 (CG2139, FBgn0028646). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (5 unique). Gene sequence location is 3R:30445635..30455867. It has the cytological map location 99F4-99F5. Protein features are: EF-hand domain; EF-hand domain pair; Mitochondrial carrier domain; Mitochondrial carrier protein; Mitochondrial substrate/solute carrier. Its molecular function is described by: calcium ion binding; transmembrane transporter activity; L-aspartate transmembrane transporter activity; L-glutamate transmembrane transporter activity. It is involved in the biological process described with: wound healing; mitochondrial transport; malate-aspartate shuttle; L-glutamate transmembrane transport; aspartate transport. 14 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0039258	beta4GalT7	-0.285171474	0.452289126	0.999936032	B4GALT7	B4GALT7	high	NA	transmembrane protein	NA	"The gene ‘_-4-galactosyltransferase 7 is referred to in FlyBase by the symbol Dmel\‘_4GalT7 (CG11780, FBgn0039258). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:25023256..25024482. It has the cytological map location 96B16. Protein features are: Beta-1,4-galactosyltransferase; Galactosyltransferase, C-terminal; Galactosyltransferase, N-terminal; Nucleotide-diphospho-sugar transferases. Its molecular function is described by: xylosylprotein 4-beta-galactosyltransferase activity; metal ion binding; galactosyltransferase activity. It is involved in the biological process described with: heparan sulfate proteoglycan biosynthetic process; carbohydrate metabolic process; chondroitin sulfate biosynthetic process; proteoglycan biosynthetic process; N-glycan processing. 9 alleles are reported. The phenotypes of these alleles manifest in: eye; wing vein L2; leg; wing blade dorsal compartment; interommatidial bristle; wing vein; wing blade posterior compartment; ommatidium; wing. The phenotypic classes of alleles include: lethal; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0037656	CG11986	-0.284861489	0.486236389	0.999936032	HMCES	HMCES	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG11986 (FBgn0037656). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:9015446..9016822. It has the cytological map location 85C2. Protein features are: SOS response associated peptidase (SRAP). Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.
FBgn0050183	CG30183	-0.284758161	0.491823256	0.999936032	NA	ANLN	low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG30183 (FBgn0050183). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:23690247..23697824. It has the cytological map location 59F6. Protein features are: PH domain-like; Pleckstrin homology domain. Its molecular function is described by: actin binding. It is involved in the biological process described with: mitotic cytokinesis. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0033266	Socs44A	-0.284556253	0.42217156	0.999936032	NA	SOCS1;SOCS6;CISH;SOCS2;SOCS3;SOCS7;SOCS4;SOCS5	high;moderate;moderate;moderate;moderate;low;low;low	NA	NA	NA	"The gene Suppressor of Cytokine Signaling at 44A is referred to in FlyBase by the symbol Dmel\Socs44A (CG2160, FBgn0033266). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:8127575..8129476. It has the cytological map location 44B3. Protein features are: SH2 domain; SOCS box domain. Its molecular function is described by: protein kinase inhibitor activity. It is involved in the biological process described with: negative regulation of JAK-STAT cascade; cytokine-mediated signaling pathway; negative regulation of protein kinase activity; positive regulation of epidermal growth factor receptor signaling pathway. 6 alleles are reported. The phenotypes of these alleles manifest in: wing vein; wing vein L3. The phenotypic classes of alleles include: viable; visible; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, during early pupal stages, in adult female stages.  "
FBgn0034956	CG4324	-0.284509928	0.356465524	0.999936032	SVOP	SVOP;SVOPL	high;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4324 (FBgn0034956). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:24014917..24017198. It has the cytological map location 60B2-60B3. Protein features are: Major facilitator superfamily domain; Major facilitator,  sugar transporter-like. Its molecular function is described by: substrate-specific transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-18 embryonic stages, during late pupal stages.  "
FBgn0038840	Grik	-0.284509928	0.356465524	0.999936032	NA	GRIK4;GRIK1;GRIK2;GRIK5;GRIK3	moderate;moderate;moderate;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\Grik (CG5621, FBgn0038840). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3R:20901956..20908263. It has the cytological map location 93A2-93A3. Protein features are: Ionotropic glutamate receptor; Ionotropic glutamate receptor, L-glutamate and glycine-binding domain; Ionotropic glutamate receptor, metazoa; Periplasmic binding protein-like I; Receptor, ligand binding region. Its molecular function is described by: kainate selective glutamate receptor activity; extracellular-glutamate-gated ion channel activity. It is involved in the biological process described with: regulation of synaptic activity; ion transport. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during late pupal stages.  "
FBgn0035987	CG3689	-0.284423467	0.431486156	0.999936032	NUDT21	NUDT21	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3689 (FBgn0035987). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:9411038..9413835. It has the cytological map location 67B5. Protein features are: Cleavage/polyadenylation specificity factor subunit 5; NUDIX hydrolase domain; NUDIX hydrolase domain-like. Its molecular function is described by: mRNA binding; hydrolase activity. It is involved in the biological process described with: mRNA polyadenylation. 6 alleles are reported. The phenotypes of these alleles manifest in: wing; mesothoracic tergum; trichogen cell; tormogen cell. The phenotypic classes of alleles include: increased mortality; visible; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0000044	Act57B	-0.284320172	0.401978526	0.999936032	NA	ACTB;ACTG1;ACTC1;ACTG2;ACTA1;ACTA2;ACTBL2;POTEI;POTEJ;POTEF;ACTRT3;ACTR1B;ACTR1A;POTEE	moderate;moderate;moderate;low;moderate;low;moderate;low;moderate;low;low;low;low;low	NA	NA	NA	"The gene Actin 57B is referred to in FlyBase by the symbol Dmel\Act57B (CG10067, FBgn0000044). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:20944021..20946431. It has the cytological map location 57B5. Protein features are: Actin family; Actin, conserved site; Actin/actin-like conserved site. Its molecular function is described by: structural constituent of cytoskeleton. It is involved in the biological process described with: cytoskeleton organization; mitotic cytokinesis; regulation of synapse organization; neuromuscular junction development, skeletal muscle fiber; heart development. 17 alleles are reported. The phenotypes of these alleles manifest in: cytoskeleton; intrinsic component of membrane; embryonic/larval neuromuscular junction; sarcomere; somatic muscle; supramolecular fiber; membrane-bounded organelle; material anatomical entity; ion channel complex; synapse; embryo; adult. The phenotypic classes of alleles include: flight defective; phenotype; increased mortality during development; lethal - all die before end of P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of moderately high expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages.  "
FBgn0032252	loh	-0.284292345	0.497248912	0.999936032	NA	THSD4;ADAMTSL4	high;moderate	NA	transmembrane protein	NA	"The gene lonely heart is referred to in FlyBase by the symbol Dmel\loh (CG6232, FBgn0032252). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 2L:10442534..10450080. It has the cytological map location 31E3. Protein features are: ADAM-TS Spacer 1; PLAC; Peptidase M12B, ADAM-TS; Thrombospondin type-1 (TSP1) repeat. Its molecular function is described by: metalloendopeptidase activity; zinc ion binding. It is involved in the biological process described with: positive regulation of extracellular matrix assembly; larval heart development. 14 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval cardial cell; embryonic/larval heart; embryonic/larval alary muscle; embryonic/larval pericardial cell. The phenotypic classes of alleles include: lethal - all die before end of larval stage; short lived; viable; lethal - all die during P-stage; cell shape defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages.  "
FBgn0003884	alphaTub84B	-0.284173668	0.391865016	0.999936032	NA	TUBA3D;TUBA3E;TUBA3C;TUBA1C;TUBA1A;TUBA1B;TUBA8;TUBA4A;TUBAL3	high;moderate;moderate;moderate;moderate;moderate;moderate;low;low	NA	NA	NA	"The gene ‘±-Tubulin at 84B is referred to in FlyBase by the symbol Dmel\‘±Tub84B (CG1913, FBgn0003884). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:7086599..7088839. It has the cytological map location 84B2. Protein features are: Alpha tubulin; Tubulin; Tubulin, conserved site; Tubulin/FtsZ, 2-layer sandwich domain; Tubulin/FtsZ, C-terminal; Tubulin/FtsZ, GTPase domain. Its molecular function is described by: GTP binding; structural constituent of cytoskeleton; GTPase activity. It is involved in the biological process described with: antimicrobial humoral response; mitotic spindle assembly checkpoint; microtubule-based process. 48 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; spermatid; melanotic mass; fat body; type II neuroblast; type I neuroblast. The phenotypic classes of alleles include: male fertile; phenotype; fertile; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period.  "
FBgn0030038	CG1440	-0.284059694	0.4505729	0.999936032	BLMH	BLMH	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1440 (FBgn0030038). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is X:8437057..8441264. It has the cytological map location 7E9. Protein features are: Cysteine peptidase, cysteine active site; Peptidase C1B, bleomycin hydrolase. Its molecular function is described by: cysteine-type endopeptidase activity; cysteine-type peptidase activity. It is involved in the biological process described with: proteolysis; homocysteine catabolic process; response to toxic substance. 9 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-06 hour embryonic stages, during early pupal stages.  "
FBgn0035432	ZnT63C	-0.283870345	0.404845126	0.999936032	SLC30A1	SLC30A1;SLC30A10	high;moderate	NA	transmembrane protein	NA	"The gene Zinc transporter 63C is referred to in FlyBase by the symbol Dmel\ZnT63C (CG17723, FBgn0035432). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (2 unique). Gene sequence location is 3L:3303708..3314009. It has the cytological map location 63C6-63D1. Protein features are: Cation efflux protein; Cation efflux protein, cytoplasmic domain. Its molecular function is described by: zinc efflux transmembrane transporter activity; zinc ion transmembrane transporter activity. It is involved in the biological process described with: zinc ion homeostasis; detoxification of zinc ion; cellular zinc ion homeostasis; regulation of sequestering of zinc ion; zinc II ion transmembrane transport. 16 alleles are reported. The phenotype of these alleles manifest in: melanotic mass. The phenotypic classes of alleles include: some die during larval stage; increased mortality; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, during early pupal stages.  "
FBgn0086680	vvl	-0.283801263	0.477650631	0.999936032	NA	POU3F2;POU3F4;POU3F3;POU3F1;POU5F1;POU5F2;POU5F1B;POU1F1;POU2F1;POU2F3	high;high;high;moderate;moderate;moderate;moderate;moderate;low;low	DNA-binding with transcription factor activity(Homeobox|Pou)	NA	NA	"The gene ventral veins lacking is referred to in FlyBase by the symbol Dmel\vvl (CG10037, FBgn0086680). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 3L:6790158..6794941. It has the cytological map location 65C5. Protein features are: Homeobox domain; Homeobox domain-like; Homeobox, conserved site; Lambda repressor-like, DNA-binding domain; POU domain; POU-domain transcription factor, class 3; POU-specific domain; Tetratricopeptide-like helical domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: transcription factor activity, sequence-specific DNA binding; RNA polymerase II distal enhancer sequence-specific DNA binding; RNA polymerase II regulatory region sequence-specific DNA binding; transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding; transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding. It is involved in the biological process described with: brain segmentation; motor neuron axon guidance; dendrite morphogenesis; positive regulation of transcription from RNA polymerase II promoter; peripheral nervous system development; brain development; positive regulation of antimicrobial peptide biosynthetic process; regulation of dendrite morphogenesis; epithelial cell fate determination, open tracheal system. 30 alleles are reported. The phenotypes of these alleles manifest in: desD neuron; abdominal dorsal sensillum campaniformium dc2; gastrula embryo; photoreceptor; medulla layer M2; optic lobe neuron; filzkorper; lateral abdominal cluster; CNS glial cell; embryonic/larval dorsal trunk. The phenotypic classes of alleles include: increased mortality; lethal; phenotype; viable; increased mortality during development; lethal - all die before end of P-stage; increased cell death; wild-type. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 06-18 hour embryonic stages.  "
FBgn0038432	CG14883	-0.283459828	0.426389696	0.999936032	GDE1	GDE1;GDPD2;GDPD5;GDPD4;GDPD3;GDPD1	high;moderate;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14883 (FBgn0038432). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:16456052..16458233. It has the cytological map location 89B17. Protein features are: Glycerophosphoryl diester phosphodiesterase; PLC-like phosphodiesterase, TIM beta/alpha-barrel domain. Its molecular function is described by: glycerophosphodiester phosphodiesterase activity. It is involved in the biological process described with: lipid metabolic process; neuron projection morphogenesis. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, in adult female stages.  "
FBgn0031231	mRpL10	-0.28341545	0.415934478	0.999936032	MRPL10	MRPL10	high	NA	NA	NA	"The gene mitochondrial ribosomal protein L10 is referred to in FlyBase by the symbol Dmel\mRpL10 (CG11488, FBgn0031231). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:203779..204782. It has the cytological map location 21B4. Protein features are: Ribosomal protein L10P. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: ribosome biogenesis; mitochondrial translation; translation. 5 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable; lethal - all die during P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0039290	CG13654	-0.2832497	0.498603939	0.999936032	NA	TMEM8B;TMEM8A;TMEM8C	high;moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13654 (FBgn0039290). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:25199818..25214255. It has the cytological map location 96C4-96C5. Protein features are: EGF-like domain; EGF-like, conserved site; Protein of unknown function DUF3522. Its molecular function is unknown. The biological processes in which it is involved are not known. 9 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages.  "
FBgn0029873	CG3918	-0.283071145	0.453695721	0.999936032	NA	SREK1IP1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3918 (FBgn0029873). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:6524464..6526342. It has the cytological map location 6B1. Protein features are: Zinc finger, CCHC-type. Its molecular function is described by: nucleic acid binding; zinc ion binding. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during pupal stage; lethal - all die before end of pupal stage; some die during pharate adult stage; lethal - all die before end of P-stage; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0085442	NKAIN	-0.28299629	0.413777506	0.999936032	NA	NKAIN3;NKAIN2;NKAIN4;NKAIN1	high;high;high;moderate	NA	transmembrane protein	NA	"The gene Na,K-ATPase Interacting is referred to in FlyBase by the symbol Dmel\NKAIN (CG34413, FBgn0085442). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (4 unique). Gene sequence location is 2R:24881570..24888615. It has the cytological map location 60E5. Protein features are: Na,K-Atpase Interacting protein. Its molecular function is described by: protein binding. It is involved in the biological process described with: regulation of sodium ion transport. 13 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: paralytic; viable; visible; uncoordinated; grooming behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0027617	CG5808	-0.282930159	0.500785133	0.999936032	PPIL4	PPIL4	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5808 (FBgn0027617). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:24814903..24817007. It has the cytological map location 96A23. Protein features are: Cyclophilin-RNA interacting protein; Cyclophilin-like domain; Cyclophilin-type peptidyl-prolyl cis-trans isomerase; Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain; PPIL4-like, cyclophilin domain; RNA recognition motif domain. Its molecular function is described by: mRNA binding; peptidyl-prolyl cis-trans isomerase activity; nucleic acid binding. It is involved in the biological process described with: mRNA splicing, via spliceosome; protein peptidyl-prolyl isomerization; regulation of phosphorylation of RNA polymerase II C-terminal domain. 7 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; embryonic/larval neuroblast; ganglion mother cell; adult thorax. The phenotypic classes of alleles include: partially lethal; increased mortality during development; lethal - all die during P-stage; phenotype; visible; increased mortality; female sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0033934	CG17385	-0.282923341	0.413944037	0.999936032	NA	ZNF454;ZNF383;ZNF502;ZNF883;ZNF286B	low;low;low;low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17385 (FBgn0033934). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:14409295..14411572. It has the cytological map location 51A1-51A2. Protein features are: Zinc finger C2H2-type. Its molecular function is described by: nucleic acid binding. The biological processes in which it is involved are not known. 5 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 00-18 hour embryonic stages, during late pupal stages, in adult female stages.  "
FBgn0261811	pico	-0.282901672	0.473510011	0.999936032	NA	RAPH1;APBB1IP;GRB10;GRB7;GRB14	high;moderate;moderate;moderate;moderate	NA	NA	NA	"The gene pico is referred to in FlyBase by the symbol Dmel\pico (CG11940, FBgn0261811). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is X:19830215..19852059. It has the cytological map location 18F2-18F4. Protein features are: PH domain-like; Pleckstrin homology domain; Ras-associating (RA) domain; Ubiquitin-related domain. Its molecular function is described by: protein domain specific binding; protein phosphatase 1 binding. It is involved in the biological process described with: lateral inhibition; signal transduction; actin filament organization; imaginal disc development; positive regulation of cell division; regulation of cell size; positive regulation of developmental growth. 35 alleles are reported. The phenotypes of these alleles manifest in: imaginal disc; wing blade dorsal compartment; chaeta; mesothoracic tergum; wing. The phenotypic classes of alleles include: visible; phenotype; size defective; cell number defective; body size defective."
FBgn0032891	Oseg5	-0.282807711	0.48617554	0.999936032	IFT80	IFT80;TRIM59	high;moderate	NA	NA	NA	"The gene Outer segment 5 is referred to in FlyBase by the symbol Dmel\Oseg5 (CG9333, FBgn0032891). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:20832849..20835840. It has the cytological map location 38F1. Protein features are: Six-bladed beta-propeller, TolB-like; Tetratricopeptide-like helical domain; WD40 repeat; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: . It is involved in the biological process described with: cilium assembly; non-motile cilium assembly. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0035232	CG12099	-0.282681862	0.418847092	0.999936032	RNF10	RNF10;RNF170	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12099 (FBgn0035232). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:1555363..1558484. It has the cytological map location 62A5. Protein features are: Zinc finger, C3HC4 RING-type; Zinc finger, RING-type; Zinc finger, RING-type, conserved site; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: metal ion binding; ubiquitin-protein transferase activity; zinc ion binding. It is involved in the biological process described with: protein autoubiquitination. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 06-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0039265	CG11790	-0.282434348	0.419913112	0.999936032	NA	ERP27;DNAJC10;TXNDC16;PDILT;PDIA6;TXNDC5;PDIA5	low;low;low;low;low;low;low	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG11790 (FBgn0039265). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3R:25047706..25049455. It has the cytological map location 96B18-96B19. Protein features are: Thioredoxin-like fold. Its molecular function is described by: protein disulfide isomerase activity. It is involved in the biological process described with: response to endoplasmic reticulum stress; apoptotic cell clearance; protein folding. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed at stages throughout the pupal period.
FBgn0014469	Cyp4e2	-0.282419281	0.414987363	0.999936032	NA	CYP4V2;CYP4A11;CYP4Z1;CYP4B1;CYP4F11;CYP4X1;CYP4F12;CYP4A22;CYP4F8;CYP46A1;CYP4F3;CYP4F2;CYP4F22	moderate;low;low;low;moderate;low;low;low;moderate;moderate;low;low;moderate	NA	transmembrane protein	NA	"The gene Cytochrome P450-4e2 is referred to in FlyBase by the symbol Dmel\Cyp4e2 (CG2060, FBgn0014469). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:8444560..8447164. It has the cytological map location 44D1. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Its molecular function is described by: heme binding; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. It is involved in the biological process described with: oxidation-reduction process. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal - majority die; pain response defective; some die during pupal stage; fertile; lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0000412	D1	-0.282406659	0.435180362	0.999936032	NA	NA	NA	DNA-binding with transcription factor activity(AT_hook)	NA	NA	"The gene D1 chromosomal protein is referred to in FlyBase by the symbol Dmel\D1 (CG9745, FBgn0000412). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:9238083..9240654. It has the cytological map location 85D1. Protein features are: AT hook, DNA-binding motif. Its molecular function is described by: satellite DNA binding; AT DNA binding. The biological processes in which it is involved are not known. 12 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: viable; visible; lethal; non-suppressor of variegation; enhancer of variegation; non-enhancer of variegation. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-12 hour embryonic stages, during early pupal stages.  "
FBgn0038072	CG6225	-0.282231699	0.497707797	0.999936032	NA	XPNPEP2;XPNPEP1	moderate;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6225 (FBgn0038072). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:12654577..12660860. It has the cytological map location 87C3. Protein features are: Aminopeptidase P; Creatinase, N-terminal; Creatinase/Aminopeptidase P, N-terminal; Creatinase/Aminopeptidase P/Spt16, N-terminal; Peptidase M24; Peptidase M24, C-terminal domain. Its molecular function is described by: metalloaminopeptidase activity. The biological processes in which it is involved are not known. 9 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; ganglion mother cell; mesothoracic tergum. The phenotypic classes of alleles include: body color defective; lethal; viable; visible; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during late pupal stages.  "
FBgn0037537	CG2767	-0.282212212	0.450974047	0.999936032	NA	AKR1A1;AKR1B15;AKR1B10;AKR1E2;AKR1D1;AKR1B1;AKR1C2;AKR1C1;AKR1C3;AKR1C4	moderate;low;low;low;low;low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG2767 (FBgn0037537). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:8005924..8008110. It has the cytological map location 84E8. Protein features are: Aldo/keto reductase; Aldo/keto reductase, conserved site; NADP-dependent oxidoreductase domain. Its molecular function is described by: oxidoreductase activity. It is involved in the biological process described with: chaeta development; wing disc development; oxidation-reduction process. 7 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 06-18 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period.  "
FBgn0266707	CR45197	-0.282031433	0.488149673	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45197 (FBgn0266707). It is a non_protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts. Gene sequence location is X:2675188..2676657. It has the cytological map location 3B1. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0034909	CG4797	-0.281836507	0.470586317	0.999936032	NA	SLC2A8;SLC2A6	moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4797 (FBgn0034909). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:23812185..23818327. It has the cytological map location 60A2. Protein features are: Major facilitator superfamily domain; Major facilitator,  sugar transporter-like; Sugar transporter, conserved site. Its molecular function is described by: sugar:proton symporter activity; glucose transmembrane transporter activity. It is involved in the biological process described with: glucose import; hexose transmembrane transport. 6 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; embryonic/larval somatic muscle. The phenotypic classes of alleles include: partially lethal - majority die; partially lethal; fertile; lethal - all die during larval stage; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during late larval stages, during early pupal stages, in adult male stages.  "
FBgn0262127	kibra	-0.281795351	0.485736148	0.999936032	NA	WWC1;WWC2;WWC3	high;high;moderate	NA	NA	NA	"The gene kibra is referred to in FlyBase by the symbol Dmel\kibra (CG33967, FBgn0262127). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:14697689..14724261. It has the cytological map location 88D1-88D2. Protein features are: C2 domain; WW domain. Its molecular function is described by: protein binding. It is involved in the biological process described with: border follicle cell migration; compound eye morphogenesis; negative regulation of glial cell proliferation; regulation of hippo signaling; regulation of transcription, DNA-templated. 53 alleles are reported. The phenotypes of these alleles manifest in: prepupa; mechanosensory sensory organ; embryo; embryonic/larval nervous system; larval thorax; oocyte nucleus; wing blade posterior compartment; eye disc; wing margin; microchaeta; ommatidium; cell component. The phenotypic classes of alleles include: cell death defective; visible; increased mortality during development; phenotype."
FBgn0013972	Gycalpha99B	-0.281787957	0.44494154	0.999936032	NA	GUCY1A2;GUCY1A3	high;moderate	NA	NA	NA	"The gene Guanylyl cyclase ‘±-subunit at 99B is referred to in FlyBase by the symbol Dmel\Gyc‘±99B (CG1912, FBgn0013972). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:29682503..29685758. It has the cytological map location 99B7. Protein features are: Adenylyl cyclase class-3/4/guanylyl cyclase; Adenylyl cyclase class-4/guanylyl cyclase, conserved site; Haem NO binding associated; Heme-NO binding; NO signalling/Golgi transport  ligand-binding domain; Nucleotide cyclase. Its molecular function is described by: heme binding; guanylate cyclase activity. It is involved in the biological process described with: rhodopsin mediated signaling pathway; intracellular signal transduction; positive phototaxis; cGMP biosynthetic process. 12 alleles are reported. The phenotypes of these alleles manifest in: photoreceptor cell R8; photoreceptor cell R7. The phenotypic classes of alleles include: viable; visual behavior defective; phototaxis defective; wild-type; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages.  "
FBgn0027619	eIF3j	-0.281776053	0.407107527	0.999936032	NA	EIF3J	high	NA	NA	NA	"The gene eukaryotic translation initiation factor 3 subunit j is referred to in FlyBase by the symbol Dmel\eIF3j (CG12131, FBgn0027619). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:9968929..9970897. It has the cytological map location 46C8-46C9. Protein features are: Eukaryotic translation initiation factor 3 subunit J; Eukaryotic translation initiation factor 3-like domain. Its molecular function is described by: protein binding; translation initiation factor activity. It is involved in the biological process described with: regulation of translational initiation; translational initiation. 12 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; embryonic/larval neuroblast; ganglion mother cell; mesothoracic tergum. The phenotypic classes of alleles include: some die during larval stage; lethal - all die before end of larval stage; increased mortality; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.  "
FBgn0261547	Exn	-0.281753476	0.449641836	0.999936032	NA	ARHGEF16;ARHGEF15;NGEF;ARHGEF19;ARHGEF5;ARHGEF26	high;moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"The gene Ephexin is referred to in FlyBase by the symbol Dmel\Exn (CG42665, FBgn0261547). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (2 unique). Gene sequence location is 3L:16970013..16994388. It has the cytological map location 73E1-73E2. Protein features are: Dbl homology (DH) domain; PH domain-like; SH3 domain. Its molecular function is described by: Rho guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: regulation of neurotransmitter secretion; positive regulation of Rho protein signal transduction; imaginal disc-derived leg morphogenesis; melanotic encapsulation of foreign target. 27 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: immune response defective; neurophysiology defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during early pupal stages.  "
FBgn0027552	CG10863	-0.281400018	0.401079524	0.999936032	NA	AKR1B10;AKR1A1;AKR1B15;AKR1E2;AKR1D1;AKR1B1;AKR1C2;AKR1C1;AKR1C3;AKR1C4	moderate;moderate;low;low;low;low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10863 (FBgn0027552). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:3941008..3942465. It has the cytological map location 64A1. Protein features are: Aldo/keto reductase; Aldo/keto reductase, conserved site; NADP-dependent oxidoreductase domain. Its molecular function is described by: oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. 8 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0027082	ProRS-m	-0.281089301	0.484892969	0.999936032	NA	PARS2	high	NA	NA	NA	"The gene Prolyl-tRNA synthetase, mitochondrial is referred to in FlyBase by the symbol Dmel\ProRS-m (CG12186, FBgn0027082). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:2650161..2651850. It has the cytological map location 62E8. Protein features are: Aminoacyl-tRNA synthetase, class II; Aminoacyl-tRNA synthetase, class II (G/ P/ S/T); Anticodon-binding; Glycyl-tRNA synthetase; Prokaryote proline-tRNA ligase core domain; Proline-tRNA ligase, class IIa. Its molecular function is described by: ATP binding; proline-tRNA ligase activity; glycine-tRNA ligase activity. It is involved in the biological process described with: prolyl-tRNA aminoacylation; glycyl-tRNA aminoacylation. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal; short lived; decreased cell size. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages, during late pupal stages, in adult female stages.  "
FBgn0266458	Fatp	-0.280640277	0.462973859	0.999936032	SLC27A4	SLC27A4;SLC27A1;SLC27A6;SLC27A5;SLC27A2;SLC27A3	moderate;moderate;low;low;low;low	NA	NA	NA	NA
FBgn0034141	CG8311	-0.280613886	0.40749171	0.999936032	NA	DOLK	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8311 (FBgn0034141). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:16587045..16589184. It has the cytological map location 53C9. Protein features are: Dolichol kinase; Polyprenol kinase family. Its molecular function is described by: dolichol kinase activity. It is involved in the biological process described with: protein glycosylation; dolichyl monophosphate biosynthetic process. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0033457	Ntmt	-0.28046742	0.440947425	0.999936032	NTMT1	NTMT1;METTL11B	high;moderate	NA	NA	NA	"The gene N-terminal methyltransferase is referred to in FlyBase by the symbol Dmel\Ntmt (CG1675, FBgn0033457). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:9865632..9867051. It has the cytological map location 46B4. Protein features are: Alpha-N-methyltransferase NTM1; S-adenosyl-L-methionine-dependent methyltransferase. Its molecular function is described by: histone methyltransferase activity; N-terminal protein N-methyltransferase activity. It is involved in the biological process described with: histone methylation; N-terminal peptidyl-proline dimethylation; N-terminal peptidyl-proline methylation. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0051719	RluA-1	-0.280378733	0.453072465	0.999936032	NA	RPUSD2	moderate	NA	NA	NA	"The gene RluA-1 is referred to in FlyBase by the symbol Dmel\RluA-1 (CG31719, FBgn0051719). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 2L:10463340..10474349. It has the cytological map location 31E6-31F1. Protein features are: Pseudouridine synthase, RluC/RluD; Pseudouridine synthase, RluC/RluD, conserved site; Pseudouridine synthase, RsuA/RluB/C/D/E/F; Pseudouridine synthase, catalytic domain. Its molecular function is described by: deaminase activity; pseudouridine synthase activity; RNA binding. It is involved in the biological process described with: enzyme-directed rRNA pseudouridine synthesis. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, during late pupal stages.  "
FBgn0028648	mRpL50	-0.280235282	0.437810486	0.999936032	NA	MRPL50	high	NA	NA	NA	"The gene mitochondrial ribosomal protein L50 is referred to in FlyBase by the symbol Dmel\mRpL50 (CG8612, FBgn0028648). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:7243080..7243933. It has the cytological map location 65E9. Protein features are: Ribosomal protein L50, mitochondria. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation. 3 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: lethal; developmental rate defective; short lived; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, during early larval stages.  "
FBgn0031247	CG11562	-0.28016961	0.460981964	0.999936032	NA	PET117	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11562 (FBgn0031247). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:292419..293222. It has the cytological map location 21B7. Protein features are: Protein Pet117, mitochondrial. Its molecular function is described by: . It is involved in the biological process described with: mitochondrial respiratory chain complex IV assembly. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0037184	CG14450	-0.280029364	0.481216123	0.999936032	NA	TEFM	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG14450 (FBgn0037184). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:22726234..22727789. It has the cytological map location 80A1. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0004907	14-3-3zeta	-0.279942988	0.398873388	0.999936032	NA	YWHAZ;YWHAB;SFN;YWHAH;YWHAG;YWHAQ;YWHAE	high;moderate;moderate;moderate;moderate;moderate;moderate	Maybe TF	NA	NA	"The gene 14-3-3‘_ is referred to in FlyBase by the symbol Dmel\14-3-3‘_ (CG17870, FBgn0004907). It is a protein_coding_gene from Drosophila melanogaster. It has 12 annotated transcripts and 12 polypeptides (3 unique). Gene sequence location is 2R:10099677..10109687. It has the cytological map location 46E6-46E8. Protein features are: 14-3-3 domain; 14-3-3 protein; 14-3-3 protein, conserved site. Its molecular function is described by: protein heterodimerization activity; protein homodimerization activity; protein binding; protein domain specific binding; protein kinase C inhibitor activity. It is involved in the biological process described with 12 unique terms, many of which group under: behavior; neurological system process; multicellular organism reproduction; protein stabilization; regulation of carbohydrate metabolic process; small GTPase mediated signal transduction; chromosome segregation; single-organism developmental process; cognition; oocyte construction; regulation of glucose metabolic process; protein modification process; protein folding; regulation of biological quality. 57 alleles are reported. The phenotypes of these alleles manifest in: membrane-bounded organelle; cellular process; anatomical space; cell; cytoplasmic vesicle; single-organism cellular process; single-organism process; endolysosome; adult head; cell cycle; embryonic/larval tracheal system; optic lobe neuron; lysosome. The phenotypic classes of alleles include: memory defective; increased mortality; fertile; viable; increased mortality during development; phenotype; lethal - all die before end of P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0030787	CG9609	-0.279931527	0.492795472	0.999936032	GTF3A	GTF3A	high	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9609 (FBgn0030787). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:16785115..16787008. It has the cytological map location 15A8. Protein features are: Zinc finger C2H2-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: nucleic acid binding. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0029821	CG4020	-0.279788712	0.427090417	0.999936032	NA	FAR1;FAR2	moderate;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4020 (FBgn0029821). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:5905746..5908001. It has the cytological map location 5C7. Protein features are: Fatty acyl-CoA reductase; Fatty acyl-CoA reductase, C-terminal; Male sterility, NAD-binding; NAD(P)-binding domain. Its molecular function is described by: fatty-acyl-CoA reductase (alcohol-forming) activity. It is involved in the biological process described with: long-chain fatty-acyl-CoA metabolic process; wax biosynthetic process. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed in adults stages of both sexes.  "
FBgn0036463	Reck	-0.279150104	0.453147801	0.999936032	RECK	RECK	high	NA	NA	NA	"The gene Reversion-inducing-cysteine-rich protein with kazal motifs is referred to in FlyBase by the symbol Dmel\Reck (CG5392, FBgn0036463). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:15001238..15014062. It has the cytological map location 71B1. Protein features are: Kazal domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 9 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed during late pupal stages.  "
FBgn0051028	CG31028	-0.279150104	0.453147801	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31028 (FBgn0051028). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:30166631..30171207. It has the cytological map location 99E1. Protein features are: Superoxide dismutase, copper/zinc binding domain. Its molecular function is described by: metal ion binding. It is involved in the biological process described with: oxidation-reduction process; superoxide metabolic process. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages.  "
FBgn0038055	trus	-0.279083945	0.473558185	0.999936032	PDCD2L	PDCD2L;PDCD2	high;moderate	NA	NA	NA	"The gene toys are us is referred to in FlyBase by the symbol Dmel\trus (CG5333, FBgn0038055). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:12456573..12458444. It has the cytological map location 87B11. Protein features are: Programmed cell death protein 2, C-terminal. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: visible; viable; lethal - all die during P-stage; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0034401	MetRS	-0.278994745	0.460610659	0.999936032	NA	MARS;MIR6758	high;moderate	NA	NA	NA	"The gene Methionyl-tRNA synthetase is referred to in FlyBase by the symbol Dmel\MetRS (CG15100, FBgn0034401). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:18846858..18850599. It has the cytological map location 55F7. Protein features are: Aminoacyl-tRNA synthetase, class I, conserved site; Aminoacyl-tRNA synthetase, class Ia, anticodon-binding; Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Methionine-tRNA ligase, type 1; Methioninyl-tRNA synthetase core domain; Methionyl-tRNA synthetase; Methionyl-tRNA synthetase, Zn-domain; Methionyl/Leucyl tRNA synthetase; Rossmann-like alpha/beta/alpha sandwich fold; S15/NS1, RNA-binding; WHEP-TRS domain. Its molecular function is described by: methionine-tRNA ligase activity; ATP binding. It is involved in the biological process described with: methionyl-tRNA aminoacylation. 10 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval neuroblast; ganglion mother cell; sarcomere; Z disc. The phenotypic classes of alleles include: viable; lethal; short lived; lethal - all die during larval stage; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0001108	DCTN1-p150	-0.278940894	0.466361782	0.999936032	NA	DCTN1	high	NA	NA	NA	"The gene Dynactin 1, p150 subunit is referred to in FlyBase by the symbol Dmel\DCTN1-p150 (CG9206, FBgn0001108). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:13929387..13934656. It has the cytological map location 70C5-70C6. Protein features are: CAP Gly-rich domain; Dynactin subunit 1; Dynein associated protein. Its molecular function is described by: dynein complex binding; microtubule binding; dynein intermediate chain binding. It is involved in the biological process described with 26 unique terms, many of which group under: organic substance transport; neurogenesis; protein localization to chromosome, centromeric region; epithelial cell differentiation; microtubule cytoskeleton organization involved in mitosis; axon extension; melanization defense response; RNA localization; establishment or maintenance of bipolar cell polarity; rhabdomere development; establishment of mitochondrion localization, microtubule-mediated; centrosome separation; secondary metabolic process; retrograde synaptic vesicle transport. 76 alleles are reported. The phenotypes of these alleles manifest in: cell component; developing material anatomical entity; microtubule organizing center; neuromuscular junction; thoracic segment; ganglion mother cell; cell projection part; embryonic/larval dorsal branch; synaptic neuropil; membrane; embryonic/larval peripheral nervous system; somatic cell of testis. The phenotypic classes of alleles include: phenotype; behavior defective; sterile; lethal - all die before end of P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0027086	IleRS	-0.278906435	0.434486188	0.999936032	NA	IARS	high	NA	NA	NA	"The gene Isoleucyl-tRNA synthetase is referred to in FlyBase by the symbol Dmel\IleRS (CG11471, FBgn0027086). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3L:22288665..22292810. It has the cytological map location 79D4. Protein features are: Aminoacyl-tRNA synthetase, class I, conserved site; Aminoacyl-tRNA synthetase, class Ia; Aminoacyl-tRNA synthetase, class Ia, anticodon-binding; Isoleucine-tRNA ligase; Isoleucine-tRNA ligase, type 2; Isoleucyl tRNA synthetase type 2, anticodon-binding domain; Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding; Rossmann-like alpha/beta/alpha sandwich fold; Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain. Its molecular function is described by: isoleucine-tRNA ligase activity; aminoacyl-tRNA editing activity; ATP binding; tRNA binding. It is involved in the biological process described with: isoleucyl-tRNA aminoacylation. 11 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval brain. The phenotypic classes of alleles include: lethal; lethal - all die during P-stage; decreased cell number. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0026373	RpII33	-0.278563371	0.46417503	0.999936032	NA	POLR2C	high	NA	NA	NA	"The gene RNA polymerase II 33kD subunit is referred to in FlyBase by the symbol Dmel\RpII33 (CG7885, FBgn0026373). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:13833337..13834306. It has the cytological map location 34D1-34D6. Protein features are: DNA-directed RNA polymerase, 30-40kDa subunit, conserved site; DNA-directed RNA polymerase, RBP11-like dimerisation domain; DNA-directed RNA polymerase, RpoA/D/Rpb3-type; DNA-directed RNA polymerase, insert domain. Its molecular function is described by: RNA polymerase II activity; DNA binding; protein dimerization activity; DNA-directed 5'-3' RNA polymerase activity. It is involved in the biological process described with: transcription from RNA polymerase II promoter; cellular response to heat. 13 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable; lethal - all die during P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0000489	Pka-C3	-0.278374724	0.503984135	0.999936032	NA	PRKX;PRKY;PRKACG;PRKACA;PRKACB	high;moderate;low;low;low	NA	NA	NA	"The gene Protein kinase, cAMP-dependent, catalytic subunit 3 is referred to in FlyBase by the symbol Dmel\Pka-C3 (CG6117, FBgn0000489). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:15925805..15954797. It has the cytological map location 72B1-72B2. Protein features are: AGC-kinase, C-terminal; Protein kinase domain; Protein kinase, ATP binding site; Protein kinase-like domain; Serine/threonine-protein kinase, active site. Its molecular function is described by: protein serine/threonine kinase activity; ATP binding; protein binding; cAMP-dependent protein kinase activity. It is involved in the biological process described with: protein phosphorylation; imaginal disc-derived wing morphogenesis. 17 alleles are reported. The phenotypes of these alleles manifest in: adult cerebrum; lamina; adult brain; neuropil; wing. The phenotypic classes of alleles include: neuroanatomy defective; phototaxis defective; fertile; viable; visible; female semi-sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed in adult male stages.  "
FBgn0052732	CG32732	-0.278270457	0.476012956	0.999936032	NA	SETD3;SETD4	high;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32732 (FBgn0052732). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:6958032..6968750. It has the cytological map location 6E3-6E4. Protein features are: Rubisco LSMT, substrate-binding domain; SET domain. Its molecular function is described by: histone methyltransferase activity (H3-K36 specific); histone methyltransferase activity (H3-K4 specific); transcription coactivator activity. It is involved in the biological process described with: peptidyl-lysine trimethylation; lateral inhibition; histone H3-K4 methylation; peptidyl-lysine dimethylation; positive regulation of transcription from RNA polymerase II promoter; histone H3-K36 methylation; peptidyl-lysine monomethylation. 9 alleles are reported. The phenotypes of these alleles manifest in: chaeta; mesothoracic tergum. The phenotypic classes of alleles include: body color defective; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, in adult female stages.  "
FBgn0030668	CG8128	-0.278252338	0.407572792	0.999936032	NUDT6	NUDT6	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8128 (FBgn0030668). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:15697494..15700034. It has the cytological map location 13E7-13E8. Protein features are: NUDIX hydrolase; NUDIX hydrolase domain; NUDIX hydrolase domain-like; NUDIX hydrolase, conserved site; Nudix hydrolase 6-like. Its molecular function is described by: hydrolase activity. It is involved in the biological process described with: regulation of cell cycle. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages, during late pupal stages.  "
FBgn0029891	Pink1	-0.277816462	0.417717581	0.999936032	NA	PINK1	high	NA	NA	NA	"The gene PTEN-induced putative kinase 1 is referred to in FlyBase by the symbol Dmel\Pink1 (CG4523, FBgn0029891). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (1 unique). Gene sequence location is X:6683798..6687302. It has the cytological map location 6C6. Protein features are: Protein kinase domain; Protein kinase-like domain; Serine/threonine-protein kinase, active site. Its molecular function is described by: protein binding; ATP binding; protein kinase activity; protein serine/threonine kinase activity. It is involved in the biological process described with 20 unique terms, many of which group under: localization; response to stress; ectopic germ cell programmed cell death; eye development; signaling; ribonucleoside triphosphate metabolic process; cellular macromolecule catabolic process; compound eye pigmentation; apoptotic process; intracellular distribution of mitochondria; negative regulation of neuron apoptotic process; nucleobase-containing small molecule metabolic process; single-organism catabolic process; single organism reproductive process; response to oxidative stress; chemical synaptic transmission. 45 alleles are reported. The phenotypes of these alleles manifest in: synaptic vesicle; cytoskeleton; dopaminergic PPL1 neuron; spermatozoon; somatic stem cell; wing blade; vacuole; embryonic/larval nervous system; mitochondrial inner membrane; motor neuron; pigment cell; endoplasmic reticulum; epithelium; exocytic vesicle; gamete; depressor muscle. The phenotypic classes of alleles include: sterile; phenotype; increased mortality; stress response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed in adult male stages.  "
FBgn0033968	hui	-0.277779841	0.500398148	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene hase und igel is referred to in FlyBase by the symbol Dmel\hui (CG10200, FBgn0033968). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:14808419..14809931. It has the cytological map location 51C3-51C4. Its molecular function is described by: . It is involved in the biological process described with: wing disc development. 6 alleles are reported. The phenotypes of these alleles manifest in: wing margin bristle; wing vein L4; trichogen cell; wing vein L3; wing; anterior crossvein. The phenotypic classes of alleles include: pain response defective; lethal; lethal - all die during P-stage; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0266635	CR45142	-0.277620722	0.479015864	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45142 (FBgn0266635). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2R:13168500..13170745. It has the cytological map location 49F4. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0037439	CG10286	-0.277393868	0.433162281	0.999936032	HEATR3	HEATR3	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10286 (FBgn0037439). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:6368965..6371115. It has the cytological map location 83E4. Protein features are: Armadillo-like helical; Armadillo-type fold. Its molecular function is described by: unfolded protein binding. It is involved in the biological process described with: protein import into nucleus; ribosomal large subunit biogenesis. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.  "
FBgn0039140	Miro	-0.277321686	0.429119805	0.999936032	RHOT1	RHOT1;RHOT2	high;moderate	NA	transmembrane protein	NA	"The gene Mitochondrial Rho is referred to in FlyBase by the symbol Dmel\Miro (CG5410, FBgn0039140). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 3R:24034362..24038847. It has the cytological map location 95D8-95D9. Protein features are: EF hand associated, type-1; EF hand associated, type-2; EF-Hand 1, calcium-binding site; EF-hand domain; EF-hand domain pair; MIRO domain; Mitochondrial Rho GTPase; P-loop containing nucleoside triphosphate hydrolase; Small GTPase superfamily. Its molecular function is described by: magnesium ion binding; calcium ion binding; GTPase activity; GTP binding; protein binding. It is involved in the biological process described with: mitochondrion localization; microtubule cytoskeleton organization; mitochondrion transport along microtubule; cellular homeostasis; synaptic vesicle transport; establishment of mitochondrion localization, microtubule-mediated; mitochondrial outer membrane permeabilization. 17 alleles are reported. The phenotypes of these alleles manifest in: embryo; axon; cytoplasmic part; extended germ band embryo; embryonic/larval nervous system; somatodendritic compartment; wing nerve; organelle; muscle system; dopaminergic neuron; neuron; supraesophageal ganglion; photoreceptor cell; dendrite. The phenotypic classes of alleles include: phenotype; increased mortality during development; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed during early pupal stages, in adult male stages.  "
FBgn0039099	GILT2	-0.277295432	0.508623486	0.999936032	NA	IFI30	moderate	NA	NA	NA	"The gene Gamma-interferon-inducible lysosomal thiol reductase 2 is referred to in FlyBase by the symbol Dmel\GILT2 (CG10157, FBgn0039099). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:23678895..23679855. It has the cytological map location 95A7. Protein features are: Gamma interferon inducible lysosomal thiol reductase GILT; Thioredoxin-like fold. Its molecular function is described by: disulfide oxidoreductase activity; oxidoreductase activity, acting on a sulfur group of donors. It is involved in the biological process described with: positive regulation of defense response to bacterium; oxidation-reduction process. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; long lived; immune response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0029801	CG15771	-0.277195925	0.422031018	0.999936032	NA	NANP	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15771 (FBgn0029801). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:5755574..5759751. It has the cytological map location 5B8. Protein features are: HAD hydrolase, subfamily IA; HAD-like domain; HAD-superfamily hydrolase, subfamily IA, CTE7. Its molecular function is described by: hydrolase activity. It is involved in the biological process described with: metabolic process. 7 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval hemocyte. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0264448	CR43866	-0.277093874	0.437139417	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR43866 (FBgn0264448). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2L:6004167..6006333. It has the cytological map location 26B2. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0032790	CG10194	-0.277033131	0.447857808	0.999936032	NUDT19	NUDT19	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10194 (FBgn0032790). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:19488682..19490104. It has the cytological map location 37E4. Protein features are: NUDIX hydrolase domain; NUDIX hydrolase domain-like. Its molecular function is described by: hydrolase activity. It is involved in the biological process described with: phagocytosis. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0050411	CG30411	-0.276991081	0.43212478	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG30411 (FBgn0050411). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:23415939..23417238. It has the cytological map location 59D11. Protein features are: Transcription activator MBF2. Its molecular function is described by: . It is involved in the biological process described with: . 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages.
FBgn0031049	Sec61gamma	-0.276741748	0.4167801	0.999936032	SEC61G	SEC61G	high	NA	transmembrane protein	NA	"The gene Sec61 ‘_ subunit is referred to in FlyBase by the symbol Dmel\Sec61‘_ (CG14214, FBgn0031049). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is X:19643327..19644518. It has the cytological map location 18D11-18D12. Protein features are: Preprotein translocase subunit SecE; Protein translocase SEC61 complex,  gamma subunit; Protein translocase SecE domain; Protein translocase complex, SecE/Sec61-gamma subunit. Its molecular function is described by: P-P-bond-hydrolysis-driven protein transmembrane transporter activity. It is involved in the biological process described with: negative regulation of autophagy; protein targeting. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: pain response defective; some die during pupal stage; lethal - all die before end of pupal stage; viable; lethal - all die during P-stage; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 06-18 hour embryonic stages, during early larval stages, during late pupal stages.  "
FBgn0039406	RpL34a	-0.276659502	0.414891903	0.999936032	NA	RPL34	high	NA	NA	NA	"The gene Ribosomal protein L34a is referred to in FlyBase by the symbol Dmel\RpL34a (CG6090, FBgn0039406). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:26058420..26059267. It has the cytological map location 96F10. Protein features are: Ribosomal protein L34Ae; Ribosomal protein L34e, conserved site. Its molecular function is described by: myosin binding; structural constituent of ribosome; RNA binding. It is involved in the biological process described with: ribosome biogenesis; cytoplasmic translation; translation. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; some die during pupal stage; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult female stages.  "
FBgn0031609	CG15443	-0.276609188	0.466822423	0.999936032	NA	TMCO6	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG15443 (FBgn0031609). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:4461657..4463447. It has the cytological map location 24F3. Protein features are: Armadillo-like helical; Armadillo-type fold. Its molecular function is unknown. It is involved in the biological process described with: lateral inhibition. 11 alleles are reported. The phenotypes of these alleles manifest in: chaeta; trichogen cell. The phenotypic classes of alleles include: visible; viable; fertile; locomotor behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0033872	CG6329	-0.276598389	0.50746816	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6329 (FBgn0033872). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (1 unique). Gene sequence location is 2R:13826371..13833503. It has the cytological map location 50C6. Its molecular function is unknown. The biological processes in which it is involved are not known. 9 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during late pupal stages, in adult male stages.  "
FBgn0028325	l(1)G0334	-0.276590799	0.410468077	0.999936032	NA	PDHA2;PDHA1	high;moderate	NA	NA	NA	"The gene lethal (1) G0334 is referred to in FlyBase by the symbol Dmel\l(1)G0334 (CG7010, FBgn0028325). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is X:4702284..4705265. It has the cytological map location 4C14. Protein features are: Dehydrogenase, E1 component; Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y; Thiamin diphosphate-binding fold. Its molecular function is described by: pyruvate dehydrogenase (acetyl-transferring) activity. It is involved in the biological process described with: acetyl-CoA biosynthetic process from pyruvate; pyruvate metabolic process. 10 alleles are reported. The phenotype of these alleles manifest in: eye photoreceptor cell. The phenotypic classes of alleles include: lethal; increased mortality; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0033504	CAP	-0.276573538	0.414737448	0.999936032	NA	SORBS1;SORBS3;SORBS2	high;high;high	NA	NA	NA	"The gene CAP is referred to in FlyBase by the symbol Dmel\CAP (CG18408, FBgn0033504). It is a protein_coding_gene from Drosophila melanogaster. It has 23 annotated transcripts and 23 polypeptides (20 unique). Gene sequence location is 2R:10269016..10307024. It has the cytological map location 46F9-47A1. Protein features are: SH3 domain; SoHo domain; Sorbin and SH3 domain-containing protein 2. Its molecular function is unknown. It is involved in the biological process described with: cell adhesion; actin filament organization; sensory perception of sound; cell migration; sensory perception of mechanical stimulus; muscle attachment. 36 alleles are reported. The phenotypes of these alleles manifest in: muscle attachment site; Johnston organ; scolopale cell. The phenotypic classes of alleles include: viable; fertile; behavior defective; neuroanatomy defective; auditory perception defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0029771	CG12730	-0.276554799	0.433870202	0.999936032	NA	CMTM4;CKLF;CMTM2;PLP2;CMTM1;CMTM6;CMTM3;CMTM5;CMTM7	moderate;low;moderate;low;moderate;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12730 (FBgn0029771). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:5516608..5518771. It has the cytological map location 5A2. Protein features are: Marvel domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 06-24 hour embryonic stages, at stages throughout the pupal period.  "
FBgn0052695	CG32695	-0.276306623	0.418792617	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32695 (FBgn0052695). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is X:9872382..9874057. It has the cytological map location 9A3. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed during early larval stages, at stages throughout the pupal period.  "
FBgn0030114	CG17754	-0.27614793	0.437838595	0.999936032	NA	KLHL5;KLHL1;KLHL4	high;moderate;moderate	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG17754 (FBgn0030114). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (4 unique). Gene sequence location is X:9250420..9255953. It has the cytological map location 8D3. Protein features are: BTB-kelch protein; BTB/Kelch-associated; BTB/POZ domain; Kelch repeat type 1; Kelch-type beta propeller; SKP1/BTB/POZ domain. Its molecular function is described by: ubiquitin-protein transferase activity. It is involved in the biological process described with: phagocytosis. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed during early pupal stages.
FBgn0050338	CG30338	-0.275950469	0.507360899	0.999936032	RWDD2A	RWDD2A;RWDD2B;RWDD3	high;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG30338 (FBgn0050338). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:9594045..9599505. It has the cytological map location 45F6. Protein features are: Domain of unknown function DUF1115; RWD domain; Ubiquitin-conjugating enzyme/RWD-like; Uncharacterised conserved protein UCP038021, RWD. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0051431	CG31431	-0.275896799	0.425093557	0.999936032	NA	FGFRL1	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31431 (FBgn0051431). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:21870681..21873640. It has the cytological map location 93F14. Protein features are: Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold. Its molecular function is unknown. The biological processes in which it is involved are not known. 8 alleles are reported. The phenotypes of these alleles manifest in: abdominal dorsal multidendritic neuron ddaD; abdominal dorsal multidendritic neuron ddaC; dendritic tree; abdominal dorsal multidendritic neuron ddaE. The phenotypic classes of alleles include: partially lethal - majority die; neuroanatomy defective; some die during pupal stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 06-24 hour embryonic stages, during late pupal stages.  "
FBgn0085234	CG34205	-0.275789617	0.245849524	0.999936032	NA	POU2AF1	low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG34205 (FBgn0085234). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:22130112..22131299. It has the cytological map location 58C1. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of no expression detected.  Peak expression observed during late pupal stages.
FBgn0035147	Gale	-0.275580258	0.4084308	0.999936032	GALE	GALE	high	NA	NA	NA	"The gene UDP-galactose 4'-epimerase is referred to in FlyBase by the symbol Dmel\Gale (CG12030, FBgn0035147). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:648555..651311. It has the cytological map location 61C8. Protein features are: NAD(P)-binding domain; Nucleotide sugar epimerase; UDP-glucose 4-epimerase. Its molecular function is described by: UDP-N-acetylglucosamine 4-epimerase activity; UDP-glucose 4-epimerase activity. It is involved in the biological process described with: larval lymph gland hemopoiesis; galactose metabolic process. 11 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; embryonic/larval lymph gland. The phenotypic classes of alleles include: partially lethal - majority die; increased mortality; body color defective; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 12-24 hour embryonic stages, during late pupal stages, in adult male stages.  "
FBgn0034753	CG2852	-0.275556421	0.408286103	0.999936032	PPIB	PPIB;PPIC	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG2852 (FBgn0034753). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:22644646..22646344. It has the cytological map location 58F3. Protein features are: Cyclophilin-like domain; Cyclophilin-type peptidyl-prolyl cis-trans isomerase; Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain; Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site. Its molecular function is described by: peptidyl-prolyl cis-trans isomerase activity. It is involved in the biological process described with: protein folding; multicellular organism reproduction; protein peptidyl-prolyl isomerization. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed within 06-12 hour embryonic stages, during early pupal stages.  "
FBgn0264894	CG44085	-0.275403142	0.462369305	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG44085 (FBgn0264894). It is a protein_coding_gene from Drosophila melanogaster. It has 13 annotated transcripts and 13 polypeptides (11 unique). Gene sequence location is 2L:13261008..13284043. It has the cytological map location 34B3-34B4. Protein features are: WD40/YVTN repeat-like-containing domain. Its molecular function is described by: MAP-kinase scaffold activity. The biological processes in which it is involved are not known. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during pupal stage; lethal - all die before end of pupal stage; viable.
FBgn0031258	CG4297	-0.275290986	0.477962663	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4297 (FBgn0031258). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:458876..472200. It has the cytological map location 21C8-21D1. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-18 embryonic stages, in adult male stages.  "
FBgn0032047	CG13088	-0.27506498	0.509417117	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13088 (FBgn0032047). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:8488981..8490546. It has the cytological map location 29D1. Protein features are: Leucine-rich repeat domain, L domain-like. Its molecular function is described by: ubiquitin-protein transferase activity. It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. 8 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed in adult male stages.  "
FBgn0030536	CG11068	-0.274764468	0.511968409	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG11068 (FBgn0030536). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:13955236..13956574. It has the cytological map location 12D1. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed in adult male stages.
FBgn0039565	CG4884	-0.274750708	0.505430093	0.999936032	NA	C6orf203	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG4884 (FBgn0039565). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:27957356..27959245. It has the cytological map location 98B6. Protein features are: RNA-binding S4 domain. Its molecular function is described by: RNA binding. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0265313	CG44286	-0.274717666	0.418148079	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG44286 (FBgn0265313). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2R:9138486..9141981. It has the cytological map location 45A11-45A12. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported.
FBgn0028552	gammaSnap1	-0.27457287	0.44651703	0.999936032	NA	NAPG	high	NA	NA	NA	"The gene ‘_ Soluble NSF attachment protein 1 is referred to in FlyBase by the symbol Dmel\‘_Snap1 (CG3988, FBgn0028552). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:24047145..24048903. It has the cytological map location 60B5. Protein features are: NSF attachment protein; Tetratricopeptide-like helical domain. Its molecular function is described by: syntaxin binding; soluble NSF attachment protein activity. It is involved in the biological process described with: neurotransmitter secretion; intracellular protein transport; regulation of cell cycle; wing disc dorsal/ventral pattern formation; synaptic vesicle priming; membrane fusion. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0028525	c(2)M	-0.274417871	0.321410117	0.999936032	NA	NA	NA	NA	NA	NA	"The gene crossover suppressor on 2 of Manheim is referred to in FlyBase by the symbol Dmel\c(2)M (CG4249, FBgn0028525). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:16303264..16305940. It has the cytological map location 35F1. Protein features are: Rad21/Rec8-like protein, N-terminal. Its molecular function is unknown. It is involved in the biological process described with: meiotic cell cycle; resolution of meiotic recombination intermediates. 18 alleles are reported. The phenotype of these alleles manifest in: synaptonemal complex. The phenotypic classes of alleles include: female fertile; viable; meiotic cell cycle defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0032054	Uba4	-0.274149508	0.449398296	0.999936032	NA	MOCS3	high	NA	NA	NA	"The gene Ubiquitin activating enzyme 4 is referred to in FlyBase by the symbol Dmel\Uba4 (CG13090, FBgn0032054). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:8517411..8519176. It has the cytological map location 29D4. Protein features are: Adenylyltransferase and sulfurtransferase MOCS3/Uba4; Rhodanese-like domain; THIF-type NAD/FAD binding fold. Its molecular function is described by: thiosulfate sulfurtransferase activity; nucleotidyltransferase activity; UFM1 activating enzyme activity; URM1 activating enzyme activity. It is involved in the biological process described with: tRNA thio-modification; Mo-molybdopterin cofactor biosynthetic process; protein urmylation; tRNA wobble position uridine thiolation. 6 alleles are reported. The phenotype of these alleles manifest in: anterior crossvein. The phenotypic classes of alleles include: visible; oxidative stress response defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0086357	Sec61alpha	-0.273749743	0.409838408	0.999936032	NA	SEC61A2;SEC61A1	high;moderate	NA	transmembrane protein	NA	"The gene Sec61 ‘± subunit is referred to in FlyBase by the symbol Dmel\Sec61‘± (CG9539, FBgn0086357). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:6477182..6480575. It has the cytological map location 26D7-26D8. Protein features are: SecY conserved site; SecY subunit domain; SecY/SEC61-alpha family; Translocon Sec61/SecY, plug domain. Its molecular function is unknown. It is involved in the biological process described with: cellular response to virus; positive regulation of viral entry into host cell; protein transport; negative regulation of autophagy; positive regulation of cell death; head involution; neuron projection morphogenesis; positive regulation of iron ion transmembrane transport; dorsal closure; cuticle development. 32 alleles are reported. The phenotypes of these alleles manifest in: embryonic/first instar larval cuticle; cephalopharyngeal skeleton; embryonic leading edge cell; embryonic/larval tracheal system; embryonic/larval midgut primordium; denticle belt; midgut constriction 2; rhabdomere R7; crystal cell; tracheal metamere. The phenotypic classes of alleles include: some die during embryonic stage; viable; lethal - all die before end of embryonic stage; stress response defective; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.  "
FBgn0038353	CG5399	-0.273735574	0.407147787	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5399 (FBgn0038353). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:15695241..15697142. It has the cytological map location 89A2. Protein features are: Calycin. Its molecular function is described by: . It is involved in the biological process described with: . 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0035272	mRpL46	-0.273610012	0.428010145	0.999936032	MRPL46	MRPL46	high	NA	NA	NA	"The gene mitochondrial ribosomal protein L46 is referred to in FlyBase by the symbol Dmel\mRpL46 (CG13922, FBgn0035272). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:1777439..1778347. It has the cytological map location 62B4. Protein features are: Mitochondrial ribosomal protein L46 NUDIX; NUDIX hydrolase domain; NUDIX hydrolase domain-like; Ribosomal protein L46. Its molecular function is described by: hydrolase activity; structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation. 4 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: lethal - all die during embryonic stage; partially lethal; pain response defective; some die during pupal stage; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in adult female stages.  "
FBgn0030352	sicily	-0.273592392	0.44171854	0.999936032	NA	NDUFAF6	high	NA	NA	NA	"The gene severe impairment of CI with lengthened youth is referred to in FlyBase by the symbol Dmel\sicily (CG15738, FBgn0030352). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:11891732..11893745. It has the cytological map location 10F4. Protein features are: Isoprenoid synthase domain; Squalene/phytoene synthase. Its molecular function is described by: transferase activity. It is involved in the biological process described with: biosynthetic process; mitochondrial respiratory chain complex I assembly; protein stabilization. 20 alleles are reported. The phenotypes of these alleles manifest in: eye photoreceptor cell; rhabdomere; retinal pigment cell; mitochondrion. The phenotypic classes of alleles include: lethal - all die during pupal stage; neurophysiology defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0002031	l(2)37Cc	-0.273503133	0.416258341	0.999936032	NA	PHB	high	NA	NA	NA	"The gene lethal (2) 37Cc is referred to in FlyBase by the symbol Dmel\l(2)37Cc (CG10691, FBgn0002031). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:19121345..19123869. It has the cytological map location 37C1. Protein features are: Band 7 domain; Prohibitin. Its molecular function is unknown. It is involved in the biological process described with: cellular response to hypoxia. 43 alleles are reported. The phenotypes of these alleles manifest in: egg; cystocyte; trichogen cell; egg chamber; mesothoracic tergum; macrochaeta; yolk; wing. The phenotypic classes of alleles include: increased mortality during development; viable; male sterile; phenotype; body color defective; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in adult female stages.  "
FBgn0034763	RYBP	-0.273479517	0.477234164	0.999936032	NA	YAF2;RYBP	high;moderate	NA	NA	NA	"The gene Ring and YY1 Binding Protein is referred to in FlyBase by the symbol Dmel\RYBP (CG12190, FBgn0034763). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:22670587..22673212. It has the cytological map location 58F7. Protein features are: Yaf2/RYBP C-terminal binding motif; Zinc finger, RanBP2-type. Its molecular function is described by: DNA binding. It is involved in the biological process described with: negative regulation of apoptotic process; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; negative regulation of immune response. 14 alleles are reported. The phenotypes of these alleles manifest in: metatarsus of male prothoracic leg; wing vein L4; embryonic/larval cuticle; eye-antennal disc; embryonic/larval integumentary system; denticle field; abdominal segment 6; wing hair; larval head segment; scutellum. The phenotypic classes of alleles include: phenotype; increased mortality; sterile; cell death defective; female fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0035591	CG4611	-0.273471803	0.497714221	0.999936032	ATP5J2-PTCD1	PTCD1;ATP5J2-PTCD1	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4611 (FBgn0035591). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:5136376..5138679. It has the cytological map location 64C7. Protein features are: Pentacotripeptide-repeat region of PRORP; Pentatricopeptide repeat. Its molecular function is described by: RNA binding; endonuclease activity. It is involved in the biological process described with: tRNA 3'-end processing; RNA modification. 3 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: lethal - all die during P-stage; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0015791	Rab14	-0.273470701	0.440842787	0.999936032	NA	RAB14	high	NA	NA	NA	"The gene Rab14 is referred to in FlyBase by the symbol Dmel\Rab14 (CG4212, FBgn0015791). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:14355145..14358764. It has the cytological map location 35A4. Protein features are: P-loop containing nucleoside triphosphate hydrolase; Ras-related protein Rab14; Small GTP-binding protein domain; Small GTPase superfamily. Its molecular function is described by: GTPase activity; GTP binding. It is involved in the biological process described with: endocytic recycling; Golgi to endosome transport; Rab protein signal transduction; phagosome acidification; vesicle-mediated transport; defense response to bacterium; regulation of endocytosis; phagolysosome assembly. 15 alleles are reported. The phenotypes of these alleles manifest in: hemocyte; phagocytic vesicle. The phenotypic classes of alleles include: fertile; flight defective; viable; wild-type; immune response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed in adult male stages.  "
FBgn0086904	Nacalpha	-0.273245736	0.411586817	0.999936032	NA	NACA;NACA2;NACAD;NACAP1	high;moderate;moderate;moderate	NA	NA	NA	"The gene Nascent polypeptide associated complex protein alpha subunit is referred to in FlyBase by the symbol Dmel\Nac‘± (CG8759, FBgn0086904). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2R:12759693..12760999. It has the cytological map location 49C2-49C3. Protein features are: Nascent polypeptide-associated complex NAC domain; Nascent polypeptide-associated complex subunit alpha. Its molecular function is described by: protein binding. It is involved in the biological process described with: oogenesis. 5 alleles are reported. The phenotypes of these alleles manifest in: sarcomere; Z disc; trichogen cell; mesothoracic tergum; ovariole; ganglion mother cell; embryonic/larval neuroblast; egg. The phenotypic classes of alleles include: phenotype; increased mortality during development; viable; lethal; increased mortality; lethal - all die before end of larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of high expression.  Peak expression observed within 06-12 hour embryonic stages, during early larval stages.  "
FBgn0026430	Grip84	-0.273171489	0.500906099	0.999936032	TUBGCP2	TUBGCP2	high	NA	NA	NA	"The gene Gamma-tubulin ring protein 84 is referred to in FlyBase by the symbol Dmel\Grip84 (CG3917, FBgn0026430). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (5 unique). Gene sequence location is X:19559431..19565764. It has the cytological map location 18D1. Protein features are: Gamma-tubulin complex component protein. Its molecular function is described by: structural constituent of cytoskeleton; microtubule binding; microtubule minus-end binding; gamma-tubulin binding. It is involved in the biological process described with 12 unique terms, many of which group under: reproduction; gamete generation; regulation of biological process; organelle fission; biological regulation; centrosome cycle; male gamete generation; regulation of cell cycle; cytoplasmic microtubule organization; multi-organism process. 12 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: increased mortality; cell cycle defective; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0052512	CG32512	-0.273016082	0.466092775	0.999936032	NA	TMEM205	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32512 (FBgn0052512). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is X:21062277..21067540. It has the cytological map location 19E7. Protein features are: Domain of unknown function DUF4149. Its molecular function is described by: . It is involved in the biological process described with: . 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; lethal - all die during larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0039360	CLS	-0.272919908	0.434258274	0.999936032	NA	CRLS1	high	NA	transmembrane protein	NA	"The gene Cardiolipin synthase is referred to in FlyBase by the symbol Dmel\CLS (CG4774, FBgn0039360). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 3R:25685236..25687370. It has the cytological map location 96E10. Protein features are: CDP-alcohol phosphatidyltransferase. Its molecular function is described by: cardiolipin synthase activity. It is involved in the biological process described with: cardiolipin biosynthetic process; mitochondrial membrane organization; ATP biosynthetic process. 5 alleles are reported. The phenotype of these alleles manifest in: mitochondrion. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0028665	VhaAC39-1	-0.272662167	0.409961604	0.999936032	NA	ATP6V0D1;ATP6V0D2	high;moderate	NA	NA	NA	NA
FBgn0035691	CG7386	-0.272635022	0.515412745	0.999936032	NA	ZNF284;ZNF341;ZNF221;ZNF44;ZNF668	low;low;low;low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7386 (FBgn0035691). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:6189745..6192049. It has the cytological map location 65A7-65A8. Protein features are: Zinc finger C2H2-type; Zinc finger, AD-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: zinc ion binding; DNA binding; transcription factor activity, sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated. 4 alleles are reported. The phenotypes of these alleles manifest in: wing; embryonic/larval neuroblast; ganglion mother cell. The phenotypic classes of alleles include: phenotype; increased mortality during development; lethal; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed during early pupal stages, in adult male stages.  "
FBgn0037141	DNApol-eta	-0.272635022	0.515412745	0.999936032	NA	POLH;POLI	high;low	NA	NA	NA	"The gene DNApol-‘‡ is referred to in FlyBase by the symbol Dmel\DNApol-‘‡ (CG7143, FBgn0037141). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:21938634..21941812. It has the cytological map location 79A4. Protein features are: DNA polymerase eta/kappa/iota/IV; DNA polymerase, Y-family, little finger domain; UmuC domain. Its molecular function is described by: damaged DNA binding; DNA-directed DNA polymerase activity. It is involved in the biological process described with: double-strand break repair via homologous recombination; response to radiation; translesion synthesis; UV protection. 10 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; mitotic spindle; trichogen cell. The phenotypic classes of alleles include: mitotic cell cycle defective; increased mortality during development; phenotype; flight defective; increased mortality; chemical sensitive. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0003900	twi	-0.272596099	0.301799031	0.999936032	NA	TWIST1;TWIST2;HAND2	high;moderate;low	DNA-binding with transcription factor activity(HLH)	NA	NA	"The gene twist is referred to in FlyBase by the symbol Dmel\twi (CG2956, FBgn0003900). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:22985374..23048325. It has the cytological map location 59C1-59C2. Protein features are: Myc-type, basic helix-loop-helix (bHLH) domain; Twist-related. Its molecular function is described by: transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; DNA binding; protein heterodimerization activity; protein homodimerization activity. It is involved in the biological process described with 17 unique terms, many of which group under: muscle tissue development; ectoderm and mesoderm interaction; RNA metabolic process; single-organism organelle organization; urogenital system development; circulatory system development; cell fate specification; dorsal/ventral axis specification; negative regulation of biological process; muscle cell development; regulation of biosynthetic process; organelle organization; regulation of muscle tissue development. 43 alleles are reported. The phenotypes of these alleles manifest in: portion of tissue; early extended germ band embryo; embryonic foregut; embryonic/larval dorsal trunk; embryonic somatic muscle; endoderm; nervous system; embryonic/larval heart; epithelium; direct flight muscle. The phenotypic classes of alleles include: increased mortality; lethal; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0051199	CG31199	-0.272596099	0.301799031	0.999936032	NA	PAMR1	low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31199 (FBgn0051199). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:20742800..20743869. It has the cytological map location 92F10. Protein features are: Peptidase S1, PA clan; Serine proteases, trypsin domain. Its molecular function is unknown. It is involved in the biological process described with: proteolysis. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0266042	CR44807	-0.272596099	0.301799031	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44807 (FBgn0266042). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2R:23812185..23814771. It has the cytological map location 60A2. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0034030	CG8192	-0.272570093	0.359338083	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG8192 (FBgn0034030). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:15544316..15549984. It has the cytological map location 52A10. Protein features are: Chitin binding domain. Its molecular function is described by: chitin binding. It is involved in the biological process described with: chitin metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late pupal stages.
FBgn0054043	CG34043	-0.272570093	0.359338083	0.999936032	NA	PROZ;PROC	low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG34043 (FBgn0054043). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:10278951..10280872. It has the cytological map location 31B1-31C4. Protein features are: Peptidase S1, PA clan. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed during early larval stages, in adult male stages.  "
FBgn0031044	MKP-4	-0.272354742	0.467878331	0.999936032	DUSP12	DUSP12;STYX;DUSP22;DUSP19;DUSP15	high;low;low;low;low	NA	NA	NA	"The gene MAPK Phosphatase 4 is referred to in FlyBase by the symbol Dmel\MKP-4 (CG14211, FBgn0031044). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:19623114..19625729. It has the cytological map location 18D7-18D8. Protein features are: Dual specificity phosphatase; Dual specificity phosphatase, catalytic domain; Dual specificity protein phosphatase 12; Dual specificity protein phosphatase domain; Protein-tyrosine phosphatase, active site; Protein-tyrosine phosphatase-like; Tyrosine specific protein phosphatases domain. Its molecular function is described by: phosphatase activity; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity. It is involved in the biological process described with: negative regulation of JUN kinase activity; protein dephosphorylation; dephosphorylation. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; female semi-sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0031948	CG7149	-0.272194832	0.467230612	0.999936032	NA	SELENOI	moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7149 (FBgn0031948). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:7786160..7790557. It has the cytological map location 28C3-28C4. Protein features are: CDP-alcohol phosphatidyltransferase; Choline/ethanolamine phosphotransferase. Its molecular function is described by: phosphotransferase activity, for other substituted phosphate groups. It is involved in the biological process described with: phospholipid biosynthetic process; phagocytosis. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages.  "
FBgn0267614	CR45952	-0.271878668	0.515455274	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45952 (FBgn0267614). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3L:21302421..21304135. It has the cytological map location 78C6. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0037960	mthl5	-0.271845841	0.425449481	0.999936032	NA	NA	NA	NA	transmembrane protein	GPCR	"The gene methuselah-like 5 is referred to in FlyBase by the symbol Dmel\mthl5 (CG6965, FBgn0037960). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:11883938..11887168. It has the cytological map location 87A1. Protein features are: GPCR, family 2, secretin-like; GPCR, family 2-like; Methuselah ectodomain, domain 2. Its molecular function is described by: G-protein coupled receptor activity. It is involved in the biological process described with: response to starvation; heart morphogenesis; cell surface receptor signaling pathway; G-protein coupled receptor signaling pathway; determination of adult lifespan. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 06-12 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0034002	CG8079	-0.271749174	0.494726031	0.999936032	NA	AGGF1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8079 (FBgn0034002). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (all unique). Gene sequence location is 2R:15218379..15224795. It has the cytological map location 51E7-51E8. Protein features are: AGGF1, OCRE domain; Forkhead-associated (FHA) domain; G-patch domain; SMAD/FHA domain. Its molecular function is described by: nucleic acid binding. It is involved in the biological process described with: mRNA splicing, via spliceosome. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0028327	l(1)G0320	-0.271647115	0.421386878	0.999936032	NA	SSR1	high	NA	transmembrane protein	NA	"The gene lethal (1) G0320 is referred to in FlyBase by the symbol Dmel\l(1)G0320 (CG32701, FBgn0028327). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:9551140..9553750. It has the cytological map location 8E7. Protein features are: Translocon-associated protein (TRAP), alpha subunit. Its molecular function is unknown. It is involved in the biological process described with: cotranslational protein targeting to membrane. 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during larval stage; viable; lethal - all die before end of larval stage; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.  "
FBgn0031850	Tsp	-0.271479756	0.51814965	0.999936032	NA	COMP;THBS3;THBS4;THBS1;THBS2	high;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene Thrombospondin is referred to in FlyBase by the symbol Dmel\Tsp (CG11326, FBgn0031850). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (3 unique). Gene sequence location is 2L:6686791..6709086. It has the cytological map location 26F7-27A1. Protein features are: Concanavalin A-like lectin/glucanase domain; EGF-like calcium-binding domain; EGF-like calcium-binding, conserved site; EGF-like domain; EGF-like, conserved site; EGF-type aspartate/asparagine hydroxylation site; Growth factor receptor cysteine-rich domain; TSP type-3 repeat; Thrombospondin, C-terminal; Thrombospondin, type 3 repeat; Thrombospondin, type 3-like repeat; Thrombospondin/cartilage oligomeric matrix protein, coiled-coil domain. Its molecular function is described by: calcium ion binding; heparin binding. It is involved in the biological process described with: cell adhesion mediated by integrin; muscle attachment; muscle organ development. 23 alleles are reported. The phenotypes of these alleles manifest in: muscle attachment site; somatic muscle; embryonic/larval muscle system; tendon cell; embryonic/larval somatic muscle. The phenotypic classes of alleles include: lethal - all die before end of embryonic stage; viable; some die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages, during late pupal stages.  "
FBgn0033752	CG8569	-0.271448301	0.514497705	0.999936032	NA	ZMYND11	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8569 (FBgn0033752). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:12519166..12521624. It has the cytological map location 49A10. Protein features are: Bromodomain; PWWP domain; ZMYND8/11, PWWP domain; Zinc finger, MYND-type. Its molecular function is described by: chromatin binding; transcription cofactor activity; zinc ion binding; RNA polymerase II regulatory region sequence-specific DNA binding; histone binding. It is involved in the biological process described with: negative regulation of transcription from RNA polymerase II promoter. 4 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0015218	eIF4E1	-0.271330962	0.419228185	0.999936032	NA	EIF4E;EIF4E1B	high;moderate	NA	NA	NA	"The gene eukaryotic translation initiation factor 4E1 is referred to in FlyBase by the symbol Dmel\eIF4E1 (CG4035, FBgn0015218). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (2 unique). Gene sequence location is 3L:9399618..9402460. It has the cytological map location 67B4. Protein features are: Eukaryotic translation initiation factor 4E (eIF-4E), conserved site; Translation Initiation factor eIF- 4e; Translation Initiation factor eIF- 4e-like. Its molecular function is described by: translation initiation factor activity; RNA 7-methylguanosine cap binding; RNA cap binding; eukaryotic initiation factor 4G binding; protein binding. It is involved in the biological process described with 19 unique terms, many of which group under: positive regulation of biological process; female meiosis chromosome segregation; animal organ morphogenesis; female meiotic nuclear division; salivary gland morphogenesis; primary metabolic process; male meiosis cytokinesis; regulation of developmental process; male meiosis chromosome segregation; salivary gland development; regulation of biological process; regulation of growth. 42 alleles are reported. The phenotypes of these alleles manifest in: adult integumentary system; ganglion mother cell; synapse; larval thoracic segment; somatic stem cell; mitotic interphase; mechanosensory chaeta; neuromuscular junction; nerve; cell cycle phase; muscle cell. The phenotypic classes of alleles include: increased mortality during development; phenotype; cell size defective; sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed within 00-06 and 12-18 hour embryonic stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0030630	CG12608	-0.271264991	0.441180521	0.999936032	PAK1IP1	PAK1IP1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12608 (FBgn0030630). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:15342857..15344625. It has the cytological map location 13B7. Protein features are: WD40 repeat; WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: . It is involved in the biological process described with: rRNA processing; cell proliferation; ribosomal large subunit biogenesis. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0025373	Fpps	-0.271210614	0.43043043	0.999936032	NA	FDPS	high	NA	NA	NA	"The gene Farnesyl pyrophosphate synthase is referred to in FlyBase by the symbol Dmel\Fpps (CG12389, FBgn0025373). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:11305511..11307528. It has the cytological map location 47F1. Protein features are: Isoprenoid synthase domain; Polyprenyl synthetase; Polyprenyl synthetase, conserved site. Its molecular function is described by: geranyltranstransferase activity; dimethylallyltranstransferase activity. It is involved in the biological process described with: wing disc development; germ cell migration; farnesyl diphosphate biosynthetic process. 9 alleles are reported. The phenotypes of these alleles manifest in: pole cell; crystal cell. The phenotypic classes of alleles include: viable; visible; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0013720	pck	-0.271129874	0.457048172	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene pickel is referred to in FlyBase by the symbol Dmel\pck (CG14779, FBgn0013720). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:1470666..1472325. It has the cytological map location 2A4. Protein features are: PMP-22/EMP/MP20/Claudin superfamily. Its molecular function is unknown. It is involved in the biological process described with: establishment of glial blood-brain barrier; liquid clearance, open tracheal system; septate junction assembly; open tracheal system development; regulation of tube size, open tracheal system. 12 alleles are reported. The phenotypes of these alleles manifest in: dorsal closure embryo; early extended germ band embryo; embryonic/larval transverse connective; abdominal 3 ventral denticle belt; late embryo; larval abdominal segment 6; non-connected developing system; dorsal trunk primordium; primary trachea; transverse connective primordium; tracheal branch primordium. The phenotypic classes of alleles include: lethal - all die before end of embryonic stage; viable; lethal; lethal - all die during embryonic stage; some die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0034059	CG8320	-0.270968618	0.434436131	0.999936032	TMEM208	TMEM208	high	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG8320 (FBgn0034059). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:15992408..15993707. It has the cytological map location 52D9-52D10. Protein features are: SRP-independent targeting protein 2/TMEM208. Its molecular function is unknown. It is involved in the biological process described with: vacuolar protein processing. 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed within 06-18 hour embryonic stages.
FBgn0037071	CG7632	-0.270870552	0.452947739	0.999936032	NA	SERHL2;SERHL	moderate;low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG7632 (FBgn0037071). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:21304697..21306197. It has the cytological map location 78C6. Protein features are: Alpha/Beta hydrolase fold; Alpha/beta hydrolase fold-1. Its molecular function is described by: . It is involved in the biological process described with: . 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages.
FBgn0024945	NitFhit	-0.270847038	0.443990376	0.999936032	NA	NIT1;FHIT	high;moderate	NA	NA	NA	"The gene Nitrilase and fragile histidine triad fusion protein is referred to in FlyBase by the symbol Dmel\NitFhit (CG7067, FBgn0024945). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:203730..205309. It has the cytological map location 61B2. Protein features are: Carbon-nitrogen hydrolase; HIT-like domain; Histidine triad (HIT) protein; Histidine triad, conserved site. Its molecular function is described by: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; bis(5'-adenosyl)-triphosphatase activity. It is involved in the biological process described with: nucleobase-containing compound metabolic process. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in stages of adults of both sexes.  "
FBgn0041702	CG15107	-0.270683934	0.493672192	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15107 (FBgn0041702). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:18971309..18972537. It has the cytological map location 56A2. Protein features are: Myb/SANT-like DNA-binding domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. The phenotypes of these alleles manifest in: myofibril; sarcomere; Z disc. The phenotypic classes of alleles include: viable; fertile; flightless. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0267108	CR45548	-0.270581276	0.376630688	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45548 (FBgn0267108). It is a pseudogene_attribute from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3R:27961443..27961821. It has the cytological map location 98B6. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0028360	Cdc7	-0.270443589	0.482587817	0.999936032	NA	CDC7	high	NA	NA	NA	"The gene Cdc7 kinase is referred to in FlyBase by the symbol Dmel\Cdc7 (CG32742, FBgn0028360). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:6654541..6659709. It has the cytological map location 6C3. Protein features are: Protein kinase domain; Protein kinase, ATP binding site; Protein kinase-like domain; Serine/threonine-protein kinase, active site. Its molecular function is described by: signal transducer, downstream of receptor, with serine/threonine kinase activity; protein kinase activity; ATP binding; histone kinase activity; protein serine/threonine kinase activity. It is involved in the biological process described with 12 unique terms, many of which group under: endomitotic cell cycle; anatomical structure formation involved in morphogenesis; instar larval or pupal development; establishment of localization; endocytosis; eggshell chorion assembly; single-multicellular organism process; DNA replication; single-organism localization; post-embryonic animal morphogenesis; positive regulation of cellular biosynthetic process. 19 alleles are reported. The phenotypes of these alleles manifest in: follicle cell; larva; embryo; trichogen cell. The phenotypic classes of alleles include: visible; female semi-sterile; phenotype; cell cycle defective; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0034883	Eglp2	-0.270331416	0.421406922	0.999936032	NA	AQP8;AQP4;AQP5;AQP2;AQP1;AQP6;MIP;AQP9	high;moderate;moderate;low;low;low;low;low	NA	transmembrane protein	NA	"The gene Entomoglyceroporin 2 is referred to in FlyBase by the symbol Dmel\Eglp2 (CG17664, FBgn0034883). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:23603722..23616754. It has the cytological map location 59F4. Protein features are: Aquaporin transporter; Aquaporin-like; Major intrinsic protein; Major intrinsic protein, conserved site. Its molecular function is described by: channel activity; water channel activity. It is involved in the biological process described with: ion transmembrane transport; transmembrane transport; renal system process. 6 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: viable; visible; short lived; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, in adult male stages.  "
FBgn0037548	CG7900	-0.270190935	0.454613363	0.999936032	NA	FAAH2;FAAH	moderate;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7900 (FBgn0037548). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:8094124..8105083. It has the cytological map location 84E11-84E12. Protein features are: Amidase signature domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the larval period.  "
FBgn0014002	Pdi	-0.270008702	0.416186952	0.999936032	P4HB	P4HB;PDIA2;PDILT;PDIA3;PDIA4	high;moderate;moderate;low;moderate	NA	NA	NA	"The gene Protein disulfide isomerase is referred to in FlyBase by the symbol Dmel\Pdi (CG6988, FBgn0014002). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:15137738..15142840. It has the cytological map location 71B5. Protein features are: Disulphide isomerase; Protein disulphide isomerase; Thioredoxin domain; Thioredoxin, conserved site; Thioredoxin-like fold. Its molecular function is described by: protein disulfide isomerase activity; peptidyl-proline 4-dioxygenase activity. It is involved in the biological process described with: cell redox homeostasis; response to endoplasmic reticulum stress; regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; protein folding. 17 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; lethal; viable; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of high expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0034266	CG4975	-0.269963446	0.475412096	0.999936032	NA	ATXN10	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4975 (FBgn0034266). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:17726914..17732987. It has the cytological map location 54E2-54E4. Protein features are: Armadillo-like helical; Armadillo-type fold; Ataxin-10 domain. Its molecular function is described by: . The biological processes in which it is involved are not known. 4 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum. The phenotypic classes of alleles include: visible; viable; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed during late pupal stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0001235	hth	-0.269729913	0.442204734	0.999936032	NA	MEIS2;MEIS1;MEIS3;PKNOX2;TGIF1	high;high;moderate;moderate;low	DNA-binding with transcription factor activity(Homeobox)	NA	NA	"The gene homothorax is referred to in FlyBase by the symbol Dmel\hth (CG17117, FBgn0001235). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 3R:10507561..10639568. It has the cytological map location 86C1-86C3. Protein features are: Homeobox KN domain; Homeobox domain; Homeobox domain-like; Homeobox protein PKNOX/Meis, N-terminal. Its molecular function is described by: protein binding; transcription factor binding; transcription coactivator binding; enhancer binding; transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; DNA binding; transcription factor activity, sequence-specific DNA binding. It is involved in the biological process described with 26 unique terms, many of which group under: cell proliferation involved in compound eye morphogenesis; peripheral nervous system development; positive regulation of signaling; haltere disc morphogenesis; imaginal disc-derived leg morphogenesis; imaginal disc pattern formation; protein import into nucleus, translocation; protein localization to nucleus; compound eye photoreceptor fate commitment; central nervous system development; salivary gland development; single-organism intracellular transport. 83 alleles are reported. The phenotypes of these alleles manifest in: presumptive embryonic/larval central nervous system; embryonic/larval digestive system; female genitalia; abdominal tergite 5; epidermis; sex comb; embryonic specialised Malpighian tubule cell; A7 neuron; tarsal segment 2; late extended germ band embryo; presumptive embryonic/larval peripheral nervous system; connective; embryonic metathoracic segment. The phenotypic classes of alleles include: neuroanatomy defective; phenotype; increased mortality during development; lethal - all die before end of embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0010482	l(2)01289	-0.269641797	0.486255974	0.999936032	NA	ERP27;DNAJC10;TXNDC16;PDILT;PDIA6;TXNDC5;PDIA5	low;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene lethal (2) 01289 is referred to in FlyBase by the symbol Dmel\l(2)01289 (CG9432, FBgn0010482). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (all unique). Gene sequence location is 2R:6721101..6740672. It has the cytological map location 42C6-42C7. Protein features are: Thioredoxin domain; Thioredoxin-like fold. Its molecular function is unknown. It is involved in the biological process described with: cell redox homeostasis. 24 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval fat body; lipid particle. The phenotypic classes of alleles include: lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.  "
FBgn0261599	RpS29	-0.269410471	0.416751637	0.999936032	NA	RPS29;LOC100288910	high;moderate	NA	NA	NA	"The gene Ribosomal protein S29 is referred to in FlyBase by the symbol Dmel\RpS29 (CG8495, FBgn0261599). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:9778042..9779528. It has the cytological map location 85E11-85E13. Protein features are: Ribosomal protein S14; Ribosomal protein S14, conserved site. Its molecular function is described by: zinc ion binding; structural constituent of ribosome. It is involved in the biological process described with: neuron development; cytoplasmic translation; translation. 11 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval neuroblast; ganglion mother cell. The phenotypic classes of alleles include: lethal - all die before end of P-stage; increased mortality during development; phenotype; increased mortality; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.  "
FBgn0262736	Vha16-1	-0.269301433	0.41423213	0.999936032	NA	ATP6V0C	moderate	NA	transmembrane protein	NA	"The gene Vacuolar H<sup>+</sup> ATPase 16kD subunit 1 is referred to in FlyBase by the symbol Dmel\Vha16-1 (CG3161, FBgn0262736). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2R:6625242..6633090. It has the cytological map location 42B2. Protein features are: V-ATPase proteolipid subunit; V-ATPase proteolipid subunit C, eukaryotic; V-ATPase proteolipid subunit C-like domain. Its molecular function is described by: proton-transporting ATPase activity, rotational mechanism. It is involved in the biological process described with: dsRNA transport; lysosomal lumen acidification; ATP hydrolysis coupled proton transport. 55 alleles are reported. The phenotypes of these alleles manifest in: adult midgut; embryonic/larval hemocyte; macrochaeta; Malpighian tubule. The phenotypic classes of alleles include: lethal - all die before end of embryonic stage; phenotype; increased mortality; fertile; some die during pupal stage."
FBgn0037102	CRIF	-0.269233105	0.439726619	0.999936032	NA	GADD45GIP1	high	NA	NA	NA	"The gene CR6-interacting factor is referred to in FlyBase by the symbol Dmel\CRIF (CG7172, FBgn0037102). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:21568059..21568898. It has the cytological map location 78D6. Protein features are: Growth arrest/ DNA-damage-inducible protein-interacting protein 1. Its molecular function is unknown. It is involved in the biological process described with: cell cycle; positive regulation of production of siRNA involved in RNA interference; positive regulation of RNA interference; cellular response to virus. 5 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: pain response defective; immune response defective; lethal - all die during larval stage; lethal - all die during second instar larval stage; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 00-06 hour embryonic stages, during early larval stages.  "
FBgn0037291	CG14662	-0.26883001	0.495102204	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14662 (FBgn0037291). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:4981999..4984232. It has the cytological map location 82E4. Protein features are: Leucine-rich repeat domain, L domain-like. Its molecular function is described by: . It is involved in the biological process described with: . 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed during late larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0033162	Glo1	-0.268401459	0.420849927	0.999936032	NA	GLO1	high	NA	NA	NA	NA
FBgn0010741	Pfdn2	-0.268237236	0.428872746	0.999936032	NA	PFDN2	high	NA	NA	NA	"The gene Prefoldin 2 is referred to in FlyBase by the symbol Dmel\Pfdn2 (CG6302, FBgn0010741). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:11073292..11074388. It has the cytological map location 68A4. Protein features are: Prefoldin beta-like; Prefoldin subunit 2. Its molecular function is described by: unfolded protein binding; protein binding involved in protein folding. It is involved in the biological process described with: phagocytosis; establishment or maintenance of neuroblast polarity; oogenesis; protein folding. 12 alleles are reported. The phenotypes of these alleles manifest in: centrosome; type I neuroblast; trichogen cell; type II neuroblast; embryonic/larval brain; spindle microtubule; oocyte; ovariole; neuroblast; mitotic spindle. The phenotypic classes of alleles include: increased mortality; viable; increased mortality during development; phenotype; lethal - all die before end of P-stage; sterile; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages.  "
FBgn0032407	Pex19	-0.268204654	0.43046092	0.999936032	NA	PEX19	high	NA	NA	NA	"The gene Peroxin 19 is referred to in FlyBase by the symbol Dmel\Pex19 (CG5325, FBgn0032407). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:12091822..12095250. It has the cytological map location 33C4. Protein features are: Pex19 protein. Its molecular function is described by: peroxisome membrane targeting sequence binding. It is involved in the biological process described with: nervous system development; peroxisome organization. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in adult male stages.  "
FBgn0025832	Fen1	-0.268200201	0.500349812	0.999936032	FEN1	FEN1	high	NA	NA	NA	"The gene Flap endonuclease 1 is referred to in FlyBase by the symbol Dmel\Fen1 (CG8648, FBgn0025832). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:16854025..16855464. It has the cytological map location 53D13-53D14. Protein features are: 5'-3' exonuclease, C-terminal domain; Flap endonuclease 1; Helix-hairpin-helix motif, class 2; PIN domain-like; XPG N-terminal; XPG conserved site; XPG-I domain; XPG/Rad2 endonuclease. Its molecular function is described by: DNA binding; nuclease activity; endonuclease activity. It is involved in the biological process described with: DNA repair. 7 alleles are reported. The phenotypes of these alleles manifest in: indirect flight muscle; embryonic/larval neuroblast; ganglion mother cell; mesothoracic tergum; neuroblast; sarcomere; myofibril. The phenotypic classes of alleles include: flightless; lethal; viable; visible; some die during embryonic stage; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0020381	Dredd	-0.268040424	0.457501252	0.999936032	NA	CASP9;CASP2;CASP8;CASP10;CASP3;CFLAR;CASP7	high;moderate;high;high;low;moderate;low	NA	NA	NA	"The gene Death related ced-3/Nedd2-like caspase is referred to in FlyBase by the symbol Dmel\Dredd (CG7486, FBgn0020381). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is X:633622..635545. It has the cytological map location 1B12-1B13. Protein features are: Caspase-like domain; Peptidase C14,  p20 domain; Peptidase C14, caspase non-catalytic subunit p10; Peptidase C14A, caspase catalytic domain. Its molecular function is described by: cysteine-type endopeptidase activity involved in execution phase of apoptosis; cysteine-type endopeptidase activity; cysteine-type endopeptidase activator activity involved in apoptotic process; protein binding; endopeptidase activity. It is involved in the biological process described with 15 unique terms, many of which group under: innate immune response; execution phase of apoptosis; germ cell development; signaling; cell death; single organism signaling; regulation of cell death; single organism reproductive process; multi-organism cellular process; macromolecule metabolic process. 19 alleles are reported. The phenotypes of these alleles manifest in: intestinal stem cell; macrochaeta; mesothoracic tergum; peptidergic neuron; spermatid. The phenotypic classes of alleles include: neuroanatomy defective; oxidative stress response defective; phenotype; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed during late larval stages, at stages throughout the pupal period.  "
FBgn0052072	Elo68alpha	-0.267741777	0.309921968	0.999936032	NA	ELOVL4;ELOVL2;ELOVL7;ELOVL5;ELOVL1	moderate;moderate;low;low;low	NA	transmembrane protein	NA	"The gene Elongase 68‘± is referred to in FlyBase by the symbol Dmel\Elo68‘± (CG32072, FBgn0052072). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:11101875..11103030. It has the cytological map location 68A6. Protein features are: ELO family; ELO family, conserved site. Its molecular function is described by: fatty acid elongase activity. It is involved in the biological process described with: fatty acid elongation, polyunsaturated fatty acid; fatty acid elongation, monounsaturated fatty acid; fatty acid elongation; pheromone biosynthetic process; long-chain fatty acid biosynthetic process; very long-chain fatty acid biosynthetic process; fatty acid elongation, saturated fatty acid; fatty acid elongation, unsaturated fatty acid; sphingolipid biosynthetic process. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: flight defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed in adult male stages.  "
FBgn0050290	Ppcdc	-0.267658104	0.456740191	0.999936032	NA	PPCDC	high	NA	NA	NA	"The gene Phosphopantothenoylcysteine decarboxylase is referred to in FlyBase by the symbol Dmel\Ppcdc (CG30290, FBgn0050290). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:21691295..21692764. It has the cytological map location 57F8-57F9. Protein features are: Flavoprotein. Its molecular function is described by: phosphopantothenoylcysteine decarboxylase activity; catalytic activity. It is involved in the biological process described with: coenzyme A biosynthetic process. 6 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; ovary. The phenotypic classes of alleles include: visible; viable; female sterile; lethal; short lived; lethal - all die during larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0260222	CG42496	-0.267658104	0.456740191	0.999936032	NA	COX19;ADAP1	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG42496 (FBgn0260222). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:21691295..21692764. It has the cytological map location 57F8-57F9. Protein features are: CHCH. Its molecular function is described by: copper ion binding. It is involved in the biological process described with: mitochondrial respiratory chain complex IV assembly; metal ion transport; aerobic respiration. No alleles are reported. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0026239	gukh	-0.26747952	0.481976787	0.999936032	NA	NHS	high	NA	NA	NA	"The gene GUK-holder is referred to in FlyBase by the symbol Dmel\gukh (CG31043, FBgn0026239). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 3R:18984025..19022436. It has the cytological map location 91E2-91E3. Protein features are: SCAR/WAVE family. Its molecular function is described by: protein binding. It is involved in the biological process described with: actin cytoskeleton organization; protein localization; axon guidance. 26 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period.  "
FBgn0027538	beta4GalNAcTA	-0.267479518	0.441476293	0.999936032	NA	B4GALT2;B4GALT3;B4GALT4;B4GALT1;B4GALT5;B4GALT6	high;moderate;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene ‘_4GalNAcTA is referred to in FlyBase by the symbol Dmel\‘_4GalNAcTA (CG8536, FBgn0027538). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:14259030..14261150. It has the cytological map location 50E6. Protein features are: Beta-1,4-galactosyltransferase; Galactosyltransferase, C-terminal; Galactosyltransferase, N-terminal; Nucleotide-diphospho-sugar transferases. Its molecular function is described by: N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity; acetylgalactosaminyltransferase activity; beta-1,4-N-acetylgalactosaminyltransferase activity. It is involved in the biological process described with: N-acetylglucosamine metabolic process; glycosphingolipid biosynthetic process; glycolipid biosynthetic process; adult locomotory behavior; neuromuscular junction development; carbohydrate metabolic process. 14 alleles are reported. The phenotypes of these alleles manifest in: A1-7 ventral longitudinal muscle 3; A1-7 ventral longitudinal muscle 4; embryonic/larval neuromuscular junction; NMJ bouton. The phenotypic classes of alleles include: phenotype; viable; fertile; locomotor behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0002626	RpL32	-0.267430373	0.419921144	0.999936032	NA	RPL32	high	NA	NA	NA	"The gene Ribosomal protein L32 is referred to in FlyBase by the symbol Dmel\RpL32 (CG7939, FBgn0002626). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3R:30045229..30046161. It has the cytological map location 99D3. Protein features are: Ribosomal protein L32e; Ribosomal protein L32e, conserved site. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: translation; cytoplasmic translation. 8 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: wild-type. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, in adult female stages.  "
FBgn0037874	Tctp	-0.26714974	0.419030053	0.999936032	TPT1	TPT1;TPT1P8;FLJ44635	high;moderate;moderate	NA	NA	NA	"The gene Translationally controlled tumor protein is referred to in FlyBase by the symbol Dmel\Tctp (CG4800, FBgn0037874). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:11210247..11211898. It has the cytological map location 86D8. Protein features are: Mss4-like; Translationally controlled tumor protein (TCTP) domain; Translationally controlled tumour protein; Translationally controlled tumour protein, conserved site. Its molecular function is described by: calcium ion binding; microtubule binding; guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: positive regulation of histone phosphorylation; regulation of stem cell differentiation; positive regulation of multicellular organism growth; cellular response to gamma radiation; mitotic G2 DNA damage checkpoint; positive regulation of cell size; double-strand break repair; intra-S DNA damage checkpoint. 13 alleles are reported. The phenotypes of these alleles manifest in: eye; 1st posterior cell; trichogen cell; male germline stem cell; imaginal disc; mesothoracic tergum; wing; testis. The phenotypic classes of alleles include: increased mortality; lethal - all die before end of prepupal stage; increased mortality during development; phenotype; lethal - all die before end of P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0032731	Swip-1	-0.267111236	0.509079213	0.999936032	NA	EFHD2;EFHD1	high;moderate	NA	NA	NA	"The gene Swiprosin-1 is referred to in FlyBase by the symbol Dmel\Swip-1 (CG10641, FBgn0032731). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:18977519..18987280. It has the cytological map location 37B8. Protein features are: EF-Hand 1, calcium-binding site; EF-hand domain; EF-hand domain pair. Its molecular function is described by: calcium ion binding. It is involved in the biological process described with: mesoderm development. 17 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: phenotype; increased mortality during development; some die during P-stage; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period.  "
FBgn0017567	ND-23	-0.267105793	0.429431901	0.999936032	NA	NDUFS8;MIR7113	high;moderate	NA	NA	NA	"The gene NADH dehydrogenase (ubiquinone) 23 kDa subunit is referred to in FlyBase by the symbol Dmel\ND-23 (CG3944, FBgn0017567). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:15836048..15837117. It has the cytological map location 89A5. Protein features are: 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; 4Fe-4S ferredoxin-type, iron-sulphur binding domain; NADH-quinone oxidoreductase, chain I. Its molecular function is described by: 4 iron, 4 sulfur cluster binding; NADH dehydrogenase activity. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone. 8 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; lethal - all die during P-stage; viable; short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 06-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0037137	Nopp140	-0.266827148	0.46066955	0.999936032	NA	NOLC1	high	NA	NA	NA	"The gene Nopp140 is referred to in FlyBase by the symbol Dmel\Nopp140 (CG7421, FBgn0037137). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 3L:21832774..21836685. It has the cytological map location 78F4. Protein features are: SRP40, C-terminal; Treacle-like, Treacher Collins Syndrome. Its molecular function is unknown. It is involved in the biological process described with: ribosome biogenesis; rRNA 2'-O-methylation. 6 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval neuroblast; ganglion mother cell; embryonic/larval midgut; mesothoracic tergum; trichogen cell; ribosome. The phenotypic classes of alleles include: visible; phenotype; some die during P-stage; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0023515	CG14814	-0.266637555	0.489101768	0.999936032	NA	GCNA	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14814 (FBgn0023515). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:1862009..1865835. It has the cytological map location 2B13. Protein features are: SprT-like; SprT-like, zinc ribbon domain. Its molecular function is unknown. It is involved in the biological process described with: DNA demethylation. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal; fertile; short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0033304	Cyp6a13	-0.266574906	0.456894998	0.999936032	CYP3A7-CYP3AP1	TBXAS1;CYP3A7-CYP3A51P;CYP3A43;CYP3A4;CYP3A5	moderate;moderate;low;low;low	NA	NA	NA	"The gene Cyp6a13 is referred to in FlyBase by the symbol Dmel\Cyp6a13 (CG2397, FBgn0033304). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:8570499..8572147. It has the cytological map location 44D3. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Its molecular function is described by: oxidoreductase activity; heme binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; iron ion binding. It is involved in the biological process described with: oxidation-reduction process; defense response to bacterium. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed in adult male stages.  "
FBgn0039223	CG5805	-0.266436354	0.446109947	0.999936032	SLC25A44	SLC25A44	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5805 (FBgn0039223). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:24784552..24787421. It has the cytological map location 96A22. Protein features are: Mitochondrial carrier domain; Mitochondrial carrier protein; Mitochondrial substrate/solute carrier. Its molecular function is described by: transmembrane transporter activity. It is involved in the biological process described with: mitochondrial transport; transmembrane transport. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0259101	CG42249	-0.266278371	0.420812292	0.999936032	NA	NT5E	moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG42249 (FBgn0259101). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:11096273..11108148. It has the cytological map location 10A4. Protein features are: 5'-Nucleotidase, C-terminal; 5'-Nucleotidase, conserved site; 5'-Nucleotidase/apyrase; Metallo-dependent phosphatase-like. Its molecular function is described by: nucleoside-triphosphatase activity; metal ion binding; nucleotide binding; nucleoside-diphosphatase activity. It is involved in the biological process described with: nucleotide catabolic process. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0035483	Mul1	-0.266143489	0.464760905	0.999936032	NA	MUL1	high	NA	transmembrane protein	NA	"The gene Mitochondrial E3 ubiquitin protein ligase 1 is referred to in FlyBase by the symbol Dmel\Mul1 (CG1134, FBgn0035483). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:4021457..4023501. It has the cytological map location 64A4. Protein features are: E3 Ubiquitin ligase, GIDE-type; Zinc finger, RING-type. Its molecular function is described by: zinc ion binding; ubiquitin-protein transferase activity. It is involved in the biological process described with: positive regulation of mitochondrial fission; protein ubiquitination. 11 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval salivary gland; mitochondrion; indirect flight muscle. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed in adult male stages.  "
FBgn0039896	yellow-h	-0.266095393	0.525307565	0.999936032	NA	DPM3	low	NA	NA	NA	"The gene yellow-h is referred to in FlyBase by the symbol Dmel\yellow-h (CG1629, FBgn0039896). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 4:227922..230428. It has the cytological map location 102B1. Protein features are: Major royal jelly protein/protein yellow; Six-bladed beta-propeller, TolB-like. Its molecular function is unknown. It is involved in the biological process described with: melanin biosynthetic process; cuticle pigmentation. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during early larval stages, at stages throughout the pupal period.  "
FBgn0260468	CG7950	-0.266022843	0.451449137	0.999936032	NA	CHCHD4	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7950 (FBgn0260468). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:30056859..30058131. It has the cytological map location 99D3. Protein features are: CHCH. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal - all die during P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed during early larval stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0027616	Ythdc1	-0.265957214	0.468283772	0.999936032	NA	YTHDC1	high	NA	NA	NA	"The gene YT521-B is referred to in FlyBase by the symbol Dmel\YT521-B (CG12076, FBgn0027616). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:3370451..3374170. It has the cytological map location 63D2. Protein features are: YTH domain. Its molecular function is described by: RNA binding; mRNA binding. It is involved in the biological process described with: regulation of alternative mRNA splicing, via spliceosome; sex determination; RNA metabolic process. 12 alleles are reported. The phenotypes of these alleles manifest in: wing; eye. The phenotypic classes of alleles include: visible; viable; lethal; locomotor behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, during early pupal stages.  "
FBgn0032130	CG3838	-0.265482505	0.462388547	0.999936032	NA	NA	NA	DNA-binding with transcription factor activity(BESS)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3838 (FBgn0032130). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:9568890..9573572. It has the cytological map location 30B12. Protein features are: BESS motif; MADF domain. Its molecular function is described by: DNA binding. The biological processes in which it is involved are not known. 16 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, during early pupal stages.  "
FBgn0040259	Ugt86Da	-0.265213158	0.425631808	0.999936032	NA	UGT2B15;UGT2B11;UGT1A3;UGT2B10;UGT8;UGT1A1;UGT2B4;UGT2B28;UGT2A2;UGT2B17;UGT2A3;UGT2B7;UGT3A1;UGT3A2;UGT1A4;UGT1A10;UGT1A7;UGT1A5;UGT1A9;UGT1A6;UGT1A8	moderate;moderate;moderate;moderate;moderate;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene Ugt86Da is referred to in FlyBase by the symbol Dmel\Ugt86Da (CG18578, FBgn0040259). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:11157098..11159744. It has the cytological map location 86D5. Protein features are: UDP-glucuronosyl/UDP-glucosyltransferase. Its molecular function is described by: glucuronosyltransferase activity; UDP-glycosyltransferase activity. It is involved in the biological process described with: UDP-glucose metabolic process. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0013772	Cyp6a8	-0.265069382	0.31129884	0.999936032	TBXAS1	TBXAS1;CYP3A43;CYP3A4;CYP3A5;CYP3A7-CYP3A51P;CYP3A7	moderate;moderate;moderate;moderate;low;low	NA	transmembrane protein	NA	"The gene Cytochrome P450-6a8 is referred to in FlyBase by the symbol Dmel\Cyp6a8 (CG10248, FBgn0013772). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:14887171..14889010. It has the cytological map location 51D1. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, E-class, group II; Cytochrome P450, conserved site. Its molecular function is described by: electron carrier activity; alkane 1-monooxygenase activity; heme binding; iron ion binding. It is involved in the biological process described with: lauric acid metabolic process; oxidation-reduction process; response to caffeine; insecticide metabolic process. 9 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0031500	CG17221	-0.265064018	0.476790649	0.999936032	RTN4IP1	RTN4IP1;TP53I3	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17221 (FBgn0031500). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:3039976..3041890. It has the cytological map location 23C5. Protein features are: Alcohol dehydrogenase, N-terminal; GroES-like; NAD(P)-binding domain; Polyketide synthase, enoylreductase domain. Its molecular function is described by: oxidoreductase activity. It is involved in the biological process described with: mushroom body development; oxidation-reduction process. 7 alleles are reported. The phenotype of these alleles manifest in: adult mushroom body. The phenotypic classes of alleles include: viable; lethal; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed in adult male stages.  "
FBgn0030511	CG11158	-0.264943607	0.443591706	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11158 (FBgn0030511). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:13682952..13684616. It has the cytological map location 12B2. Protein features are: Inosine/uridine-preferring nucleoside hydrolase; Inosine/uridine-preferring nucleoside hydrolase domain. Its molecular function is described by: purine nucleosidase activity. It is involved in the biological process described with: purine nucleoside catabolic process. 2 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: some die during pupal stage; partially lethal - majority die; viable; body color defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 06-24 hour embryonic stages, during early larval stages, in stages of adults of both sexes.  "
FBgn0033027	TpnC4	-0.264920154	0.285334535	0.999936032	NA	CALM1;CALML3;CALML4;CABP4;CALM3;CABP5;CALM2;CALML5;CABP7;CABP1;CABP2;CALN1;CALML6	moderate;moderate;low;moderate;low;moderate;low;low;moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"The gene Troponin C isoform 4 is referred to in FlyBase by the symbol Dmel\TpnC4 (CG12408, FBgn0033027). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:5503437..5507866. It has the cytological map location 41F2-41F3. Protein features are: EF-Hand 1, calcium-binding site; EF-hand domain; EF-hand domain pair. Its molecular function is described by: calcium ion binding. It is involved in the biological process described with: flight. 8 alleles are reported. The phenotypes of these alleles manifest in: sarcomere; Z disc; indirect flight muscle. The phenotypic classes of alleles include: flightless; jump response defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0039685	Obp99b	-0.264920154	0.285334535	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Odorant-binding protein 99b is referred to in FlyBase by the symbol Dmel\Obp99b (CG7592, FBgn0039685). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:29716254..29716896. It has the cytological map location 99B8. Protein features are: Pheromone/general odorant binding protein. Its molecular function is described by: odorant binding. It is involved in the biological process described with: sensory perception of smell; salivary gland cell autophagic cell death; response to pheromone; olfactory behavior; autophagic cell death; sensory perception of chemical stimulus. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: mating defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of no expression detected.  Peak expression observed during late larval stages, at stages throughout the pupal period.  "
FBgn0032820	fbp	-0.264686686	0.442774054	0.999936032	NA	FBP2;FBP1	high;moderate	NA	NA	NA	"The gene fructose-1,6-bisphosphatase is referred to in FlyBase by the symbol Dmel\fbp (CG31692, FBgn0032820). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 2L:19761587..19764136. It has the cytological map location 38A2-38A3. Protein features are: Fructose-1,6-bisphosphatase; Fructose-1,6-bisphosphatase class 1; Fructose-1,6-bisphosphatase, active site; Fructose-1-6-bisphosphatase class I, N-terminal. Its molecular function is described by: fructose 1,6-bisphosphate 1-phosphatase activity. It is involved in the biological process described with: fructose 6-phosphate metabolic process; fructose 1,6-bisphosphate metabolic process; sucrose biosynthetic process; fructose metabolic process; gluconeogenesis. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0062449	CG13197	-0.264637487	0.505167899	0.999936032	NA	DUSP11	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13197 (FBgn0062449). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:11691285..11697785. It has the cytological map location 48C2. Protein features are: Dual specificity phosphatase, catalytic domain; Dual specificity protein phosphatase domain; Protein-tyrosine phosphatase, active site; Protein-tyrosine phosphatase-like; Tyrosine specific protein phosphatases domain. Its molecular function is described by: protein tyrosine/serine/threonine phosphatase activity; protein tyrosine phosphatase activity. It is involved in the biological process described with: protein dephosphorylation. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: female semi-sterile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0039965	CG13865	-0.264543998	0.447477659	0.999936032	NA	COA7	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13865 (FBgn0039965). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:23013495..23016586. It has the cytological map location 20F3-20F4. Protein features are: Sel1-like repeat. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: flightless; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.  "
FBgn0015806	S6k	-0.264526964	0.42912174	0.999936032	NA	RPS6KB1;RPS6KB2;RPS6KA2;RPS6KA1;RPS6KA3;AKT1;AKT3;AKT2;SGK1;SGK2;RPS6KA4;RPS6KA5;RPS6KA6;SGK3	high;high;low;low;low;low;low;low;low;low;low;low;low;low	NA	NA	NA	NA
FBgn0037448	CG15186	-0.264526886	0.526747344	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15186 (FBgn0037448). It is a protein_coding_gene from Drosophila melanogaster. It has 12 annotated transcripts and 12 polypeptides (10 unique). Gene sequence location is 3R:6478311..6495025. It has the cytological map location 83E8-83F1. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult male stages.  "
FBgn0038195	CG3061	-0.264482878	0.434301823	0.999936032	DNAJB12	DNAJB12;DNAJB14;DNAJC18	high;moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3061 (FBgn0038195). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:14032371..14035041. It has the cytological map location 88A4. Protein features are: DnaJ domain; Domain of unknown function DUF1977, DnaJ-like. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal; lethal - all die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 00-18 hour embryonic stages, during late pupal stages, in adult male stages.  "
FBgn0261612	CngA	-0.264346709	0.513353957	0.999936032	NA	CNGA3;CNGA2;CNGA1;CNGA4	high;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene Cyclic nucleotide-gated ion channel subunit A is referred to in FlyBase by the symbol Dmel\CngA (CG42701, FBgn0261612). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:16243145..16259805. It has the cytological map location 53A2. Protein features are: Cyclic nucleotide-binding domain; Cyclic nucleotide-binding, conserved site; Cyclic nucleotide-binding-like; Cyclic nucleotide-gated channel, C-terminal leucine zipper domain; Ion transport domain; RmlC-like jelly roll fold. Its molecular function is described by: voltage-gated potassium channel activity; intracellular cyclic nucleotide activated cation channel activity. It is involved in the biological process described with: regulation of membrane potential; cGMP-mediated signaling; response to hypoxia; transmembrane transport; cation transport. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: stress response defective; lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult male stages.  "
FBgn0031529	CG9662	-0.264174719	0.489964051	0.999936032	NA	OSTC	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9662 (FBgn0031529). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:3375832..3376737. It has the cytological map location 23F1. Protein features are: Oligosaccharyl transferase complex, subunit OST3/OST6. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0086450	su(r)	-0.264013648	0.440076527	0.999936032	NA	DPYD	high	NA	NA	NA	"The gene suppressor of rudimentary is referred to in FlyBase by the symbol Dmel\su(r) (CG2194, FBgn0086450). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:9196808..9201820. It has the cytological map location 8D1. Protein features are: 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; 4Fe-4S ferredoxin-type, iron-sulphur binding domain; Aldolase-type TIM barrel; Alpha-helical ferredoxin; Dihydroorotate dehydrogenase domain; Dihydroorotate dehydrogenase, conserved site; Dihydroprymidine dehydrogenase domain II; FAD/NAD(P)-binding domain. Its molecular function is described by: iron-sulfur cluster binding; dihydroorotate dehydrogenase activity. It is involved in the biological process described with: 'de novo' pyrimidine nucleobase biosynthetic process; oxidation-reduction process. 23 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile; chemical sensitive. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during early larval stages.  "
FBgn0000053	ade3	-0.263707575	0.489438328	0.999936032	NA	GART	high	NA	NA	NA	"The gene adenosine 3 is referred to in FlyBase by the symbol Dmel\ade3 (CG31628, FBgn0000053). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:7014623..7023898. It has the cytological map location 27D4. Protein features are: AIR synthase-related protein, C-terminal domain; ATP-grasp fold; ATP-grasp fold, subdomain 1; Formyl transferase, N-terminal; Phosphoribosylformylglycinamidine cyclo-ligase; Phosphoribosylglycinamide formyltransferase; Phosphoribosylglycinamide formyltransferase, active site; Phosphoribosylglycinamide synthetase; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C-domain; Phosphoribosylglycinamide synthetase, N-terminal; Phosphoribosylglycinamide synthetase, conserved site; Pre-ATP-grasp domain; PurM-like, N-terminal domain; Rudiment single hybrid motif. Its molecular function is described by: metal ion binding; phosphoribosylamine-glycine ligase activity; phosphoribosylformylglycinamidine cyclo-ligase activity; phosphoribosylglycinamide formyltransferase activity; ATP binding. It is involved in the biological process described with: 'de novo' IMP biosynthetic process; purine nucleobase biosynthetic process. 20 alleles are reported. The phenotypes of these alleles manifest in: tarsal segment; dorsal row; trichome of the posterior wing margin; ventral row; wing vein; macrochaeta; pigment cell; wing. The phenotypic classes of alleles include: visible; eye color defective; viable; lethal; auxotroph. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0038082	CG5724	-0.263312745	0.435431842	0.999936032	UGT1A3	UGT1A3;UGT2B10;UGT1A1;UGT3A1;UGT8;UGT2B4;UGT2B15;UGT2B28;UGT2A2;UGT3A2;UGT2B17;UGT2B11;UGT2A3;UGT2B7	moderate;low;low;low;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG5724 (FBgn0038082). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:12739642..12741417. It has the cytological map location 87C8. Protein features are: UDP-glucuronosyl/UDP-glucosyltransferase. Its molecular function is described by: glucuronosyltransferase activity. It is involved in the biological process described with: metabolic process. 4 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: lethal - all die during embryonic stage; partially lethal - majority die; some die during pupal stage; lethal; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period.
FBgn0031301	CG14339	-0.263269888	0.421731729	0.999936032	NA	CDC27;CFAP70	low;low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG14339 (FBgn0031301). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:1108540..1112694. It has the cytological map location 21F1. Protein features are: Tetratricopeptide repeat; Tetratricopeptide repeat-containing domain; Tetratricopeptide-like helical domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed in adult male stages.
FBgn0261561	CG42675	-0.263269888	0.421731729	0.999936032	NA	ZC2HC1C;ZC2HC1A;ZC2HC1B	high;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG42675 (FBgn0261561). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (4 unique). Gene sequence location is 3R:5813609..5818820. It has the cytological map location 83C4. Protein features are: Zinc finger C2HC domain-containing protein. Its molecular function is described by: . It is involved in the biological process described with: . 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; flightless; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0263746	CR43671	-0.263269888	0.421731729	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR43671 (FBgn0263746). It is a pseudogene_attribute from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2L:16728035..16729681. It has the cytological map location 36A12. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available.
FBgn0033215	CG1942	-0.263246072	0.31209097	0.999936032	MOGAT2	MOGAT2;DGAT2L6;DGAT2;MOGAT1;AWAT1;MOGAT3;AWAT2;DGAT2L7P	high;moderate;moderate;moderate;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1942 (FBgn0033215). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:7712578..7714182. It has the cytological map location 43E12. Protein features are: Diacylglycerol acyltransferase. Its molecular function is described by: transferase activity, transferring acyl groups other than amino-acyl groups. It is involved in the biological process described with: mesoderm development. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0036825	RpL26	-0.263202342	0.42649792	0.999936032	RPL26	RPL26L1;RPL26	high;high	NA	NA	NA	"The gene Ribosomal protein L26 is referred to in FlyBase by the symbol Dmel\RpL26 (CG6846, FBgn0036825). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3L:18898875..18900408. It has the cytological map location 75E4. Protein features are: KOW; Ribosomal protein L2 domain 2; Ribosomal protein L24/L26, conserved site; Ribosomal protein L26/L24, eukaryotic/archaeal; Translation protein SH3-like domain. Its molecular function is described by: structural constituent of ribosome; RNA binding. It is involved in the biological process described with: ribosomal large subunit biogenesis; translation; cytoplasmic translation. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal; some die during larval stage; viable; lethal; lethal - all die during larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0030061	CG1785	-0.263201776	0.470436725	0.999936032	GLTSCR2	GLTSCR2	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1785 (FBgn0030061). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:8714936..8717065. It has the cytological map location 8A2. Protein features are: Ribosome biogenesis protein Nop53/GLTSCR2. Its molecular function is described by: rRNA binding. It is involved in the biological process described with: ribosomal large subunit assembly; ribosomal large subunit export from nucleus. 2 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval neuroblast; ganglion mother cell. The phenotypic classes of alleles include: lethal; viable; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0039623	CG1951	0.263582291	0.501412857	0.999936032	SCYL2	SCYL2	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1951 (FBgn0039623). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:29027236..29030938. It has the cytological map location 98F5. Protein features are: Armadillo-like helical; Armadillo-type fold; Protein kinase domain; Protein kinase-like domain. Its molecular function is described by: ATP binding. It is involved in the biological process described with: multicellular organism reproduction. 11 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; female sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0033097	Zip42C.2	0.263805339	0.457876012	0.999936032	NA	SLC39A3;SLC39A1;SLC39A2	high;moderate;low	NA	transmembrane protein	NA	"The gene Zinc/iron regulated transporter-related protein 42C.2 is referred to in FlyBase by the symbol Dmel\Zip42C.2 (CG9430, FBgn0033097). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:6718196..6719533. It has the cytological map location 42C6. Protein features are: Zinc/iron permease. Its molecular function is described by: zinc ion transmembrane transporter activity. It is involved in the biological process described with: detoxification of zinc ion; zinc II ion transmembrane import. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die during pupal stage; lethal - all die during larval stage; viable; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed in adults stages of both sexes.  "
FBgn0028375	heix	0.264042892	0.470955447	0.999936032	NA	UBIAD1	high	NA	transmembrane protein	NA	"The gene heixuedian is referred to in FlyBase by the symbol Dmel\heix (CG5876, FBgn0028375). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:16296051..16299858. It has the cytological map location 35F1. Protein features are: UbiA prenyltransferase domain containing protein 1; UbiA prenyltransferase family. Its molecular function is described by: prenyltransferase activity. It is involved in the biological process described with 12 unique terms, many of which group under: multicellular organismal process; negative regulation of immune system process; cellular component morphogenesis; vitamin metabolic process; lamellocyte differentiation; regulation of phosphorus metabolic process; regulation of hemocyte proliferation; Ras protein signal transduction; macromolecule modification; cell differentiation. 15 alleles are reported. The phenotypes of these alleles manifest in: wing; secondary lobe of embryonic/larval lymph gland; wing vein; mesothoracic tergum; crystal cell; embryonic/larval hemocyte; hemocyte; melanotic mass; trichogen cell; imaginal disc. The phenotypic classes of alleles include: melanotic mass phenotype; small body; viable; visible; fertile; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, in adult female stages.  "
FBgn0037130	Syn1	0.264092273	0.529433677	0.999936032	NA	SNTB1;SNTB2;SNTA1	high;moderate;moderate	NA	NA	NA	"The gene Syntrophin-like 1 is referred to in FlyBase by the symbol Dmel\Syn1 (CG7152, FBgn0037130). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 3L:21745359..21770534. It has the cytological map location 78E6-78F1. Protein features are: PDZ domain; PH domain-like; Pleckstrin homology domain; Syntrophin; Syntrophin-1. Its molecular function is described by: structural constituent of muscle; cytoskeletal protein binding. It is involved in the biological process described with: locomotion; regulation of synaptic growth at neuromuscular junction. 13 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal - majority die; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period.  "
FBgn0036828	CG6841	0.264178695	0.511498299	0.999936032	PRPF6	PRPF6	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6841 (FBgn0036828). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:18905372..18908974. It has the cytological map location 75E4-75E5. Protein features are: HAT (Half-A-TPR) repeat; PRP1 splicing factor, N-terminal; Pre-mRNA-processing factor 6/Prp1/STA1; Tetratricopeptide repeat; Tetratricopeptide repeat-containing domain; Tetratricopeptide-like helical domain. Its molecular function is described by: RNA binding. It is involved in the biological process described with: spliceosomal tri-snRNP complex assembly; mRNA splicing, via spliceosome; regulation of alternative mRNA splicing, via spliceosome. 5 alleles are reported. The phenotypes of these alleles manifest in: pulvillus; tarsal segment; ganglion mother cell; embryonic/larval neuroblast; unguis; antenna. The phenotypic classes of alleles include: neuroanatomy defective; some die during pupal stage; lethal; female sterile; lethal - all die during P-stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0024189	sns	0.264561839	0.432438571	0.999936032	NA	NPHS1;PRODH2	high;moderate	NA	transmembrane protein	NA	"The gene sticks and stones is referred to in FlyBase by the symbol Dmel\sns (CG33141, FBgn0024189). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 2R:8798489..8856091. It has the cytological map location 44F1. Protein features are: CD80-like, immunoglobulin C2-set; Fibronectin type III; Immunoglobulin I-set; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold. Its molecular function is described by: protein binding. It is involved in the biological process described with 11 unique terms, many of which group under: cell adhesion; biological adhesion; cell-cell adhesion via plasma-membrane adhesion molecules; cell-cell adhesion; cellular component organization or biogenesis; single-multicellular organism process; male gamete generation; cytoskeleton organization; nephrocyte filtration; larval visceral muscle development; muscle cell differentiation; compound eye development; renal filtration; nephrocyte diaphragm assembly; multi-organism process. 64 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval brain; ommatidium; A1-7 dorsal acute muscle 1; nephrocyte diaphragm; circular visceral muscle fiber; cell-cell junction; male germline cyst; embryonic/larval midgut primordium; central nervous system; cell junction; embryonic/larval visceral muscle; visceral mesoderm derivative. The phenotypic classes of alleles include: cell adhesion defective; lethal; increased mortality during development; viable; lethal - all die during P-stage; phenotype; visible; sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 06-18 hour embryonic stages, during early pupal stages.  "
FBgn0037115	CG11249	0.264561839	0.432438571	0.999936032	NA	PKM;PKLR	moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11249 (FBgn0037115). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:21672139..21674518. It has the cytological map location 78E3. Protein features are: Pyruvate kinase; Pyruvate kinase, C-terminal; Pyruvate kinase, barrel; Pyruvate kinase-like, insert domain. Its molecular function is described by: potassium ion binding; pyruvate kinase activity; magnesium ion binding. It is involved in the biological process described with: glycolytic process. 10 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0040208	Kat60	0.264628506	0.49317418	0.999936032	NA	KATNAL1;KATNA1;KATNAL2	high;moderate;low	NA	NA	NA	"The gene Katanin 60 is referred to in FlyBase by the symbol Dmel\Kat60 (CG10229, FBgn0040208). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:5227289..5232209. It has the cytological map location 82F6. Protein features are: AAA+ ATPase domain; ATPase, AAA-type, conserved site; ATPase, AAA-type, core; Katanin p60 subunit A1; P-loop containing nucleoside triphosphate hydrolase; Vps4 oligomerisation, C-terminal. Its molecular function is described by: ATPase activity; myosin binding; ATP binding; microtubule-severing ATPase activity; microtubule binding. It is involved in the biological process described with: mitotic sister chromatid segregation; microtubule-based process; wing disc development; microtubule severing; dendrite development; microtubule depolymerization; chaeta development; regulation of synaptic growth at neuromuscular junction; cytoplasmic microtubule organization; negative regulation of cell migration. 15 alleles are reported. The phenotypes of these alleles manifest in: dendritic tree; adult mushroom body; NMJ bouton; microtubule; class IV dendritic arborizing neuron; mushroom body alpha-lobe; Kenyon cell. The phenotypic classes of alleles include: lethal; neurophysiology defective; viable; neuroanatomy defective; some die during pupal stage; majority die during larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0003575	su(sable)	0.264784414	0.479410622	0.999936032	NA	ZC3H6;ZC3H4;ZC3H8	high;high;moderate	DNA-binding with transcription factor activity	NA	NA	"The gene suppressor of sable is referred to in FlyBase by the symbol Dmel\su(sable) (CG6222, FBgn0003575). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:635890..643760. It has the cytological map location 1B13. Protein features are: WD40/YVTN repeat-like-containing domain; Zinc finger, CCCH-type. Its molecular function is described by: RNA binding; metal ion binding. It is involved in the biological process described with: nuclear RNA surveillance; negative regulation of transcription, DNA-templated. 161 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: increased mortality; increased mortality during development; viable; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early pupal stages, in adult female stages.  "
FBgn0037855	CG6621	0.26505432	0.525566643	0.999936032	NA	TTC14	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG6621 (FBgn0037855). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:10889768..10893531. It has the cytological map location 86C7. Protein features are: Tetratricopeptide repeat; Tetratricopeptide repeat-containing domain; Tetratricopeptide-like helical domain. Its molecular function is described by: . The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0085212	CG34183	0.26505432	0.525566643	0.999936032	NA	RPAP2	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG34183 (FBgn0085212). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:9890061..9890772. It has the cytological map location 30E1. Protein features are: Protein of unknown function DUF408. Its molecular function is described by: CTD phosphatase activity. It is involved in the biological process described with: dephosphorylation of RNA polymerase II C-terminal domain; snRNA transcription. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0038327	Trax	0.265200757	0.480653598	0.999936032	TSNAX	TSNAX	high	NA	NA	NA	"The gene Translin associated factor X is referred to in FlyBase by the symbol Dmel\Trax (CG5063, FBgn0038327). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:15361692..15362850. It has the cytological map location 88F1. Protein features are: Translin family; Translin, N-terminal. Its molecular function is described by: endoribonuclease activity; sequence-specific DNA binding. It is involved in the biological process described with: RNA phosphodiester bond hydrolysis, endonucleolytic. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: female fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.  "
FBgn0037734	trbd	0.265358448	0.509815392	0.999936032	ZRANB1	ZRANB1	high	NA	NA	NA	"The gene trabid is referred to in FlyBase by the symbol Dmel\trbd (CG9448, FBgn0037734). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:9705996..9711037. It has the cytological map location 85E5. Protein features are: OTU domain; Zinc finger, RanBP2-type. Its molecular function is described by: thiol-dependent ubiquitinyl hydrolase activity; K63-linked polyubiquitin binding; thiol-dependent ubiquitin-specific protease activity; protein binding. It is involved in the biological process described with: protein deubiquitination; protein K29-linked deubiquitination; protein K63-linked deubiquitination; positive regulation of Wnt signaling pathway; protein deubiquitination involved in ubiquitin-dependent protein catabolic process; cytoskeleton organization; cell migration; protein K33-linked deubiquitination. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: locomotor behavior defective; short lived; fertile; lethal - all die during P-stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed in adult male stages.  "
FBgn0038325	Atg4b	0.265535343	0.487654119	0.999936032	NA	ATG4D;ATG4C;ATG4B;ATG4A	high;moderate;low;low	NA	NA	NA	"The gene Autophagy-related 4b is referred to in FlyBase by the symbol Dmel\Atg4b (CG6194, FBgn0038325). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:15353720..15356924. It has the cytological map location 88F1. Protein features are: Peptidase C54. Its molecular function is described by: cysteine-type endopeptidase activity. It is involved in the biological process described with: autophagic cell death; autophagy; C-terminal protein lipidation; protein delipidation; mitophagy; protein targeting to membrane; nucleophagy; autophagosome assembly; salivary gland cell autophagic cell death. 8 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; chaeta. The phenotypic classes of alleles include: visible; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, during early pupal stages, in adult female stages.  "
FBgn0035371	AhcyL1	0.266115862	0.438922614	0.999936032	NA	AHCYL1;AHCYL2;AHCY	high;high;low	NA	NA	NA	"The gene Adenosylhomocysteinase like 1 is referred to in FlyBase by the symbol Dmel\AhcyL1 (CG9977, FBgn0035371). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:2768466..2772325. It has the cytological map location 62F3. Protein features are: Adenosylhomocysteinase-like; NAD(P)-binding domain; S-adenosyl-L-homocysteine hydrolase, NAD binding domain; S-adenosyl-L-homocysteine hydrolase, conserved site. Its molecular function is described by: adenosylhomocysteinase activity. It is involved in the biological process described with: one-carbon metabolic process; S-adenosylmethionine cycle. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: long lived; aging defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, during early pupal stages.  "
FBgn0038924	CG6028	0.266215103	0.42240542	0.999936032	FAHD2A	FAHD2A;FAHD2B;FAHD1	high;moderate;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6028 (FBgn0038924). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:22024259..22025506. It has the cytological map location 94A1. Protein features are: Fumarylacetoacetase, C-terminal-related. Its molecular function is described by: catalytic activity. It is involved in the biological process described with: metabolic process. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed at stages throughout the larval period.  "
FBgn0065099	snRNA:7SK	0.266246876	0.515720008	0.999936032	NA	NA	NA	NA	NA	NA	"The gene small nuclear RNA 7SK is referred to in FlyBase by the symbol Dmel\snRNA:7SK (CR33925, FBgn0065099). It is a snRNA_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3R:7474553..7474996. It has the cytological map location 84D8. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 06-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  CAVEAT: These RNA-Seq temporal profiles depend upon RNA-Seq reads that are uniquely placed in the genome.  For this reason, genes such as histones, Stellates and many classes of RNA genes that are present in multiple exact or near exact copies in the genome, expression levels may be reported as much lower than their true values."
FBgn0265301	CR44274	0.266304375	0.505013453	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44274 (FBgn0265301). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2R:8943495..8944295. It has the cytological map location 44F9. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0026593	CG5707	0.266407294	0.43904254	0.999936032	NA	SERHL2;SERHL	moderate;low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG5707 (FBgn0026593). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:2189160..2192221. It has the cytological map location 62D2. Protein features are: Alpha/Beta hydrolase fold; Alpha/beta hydrolase fold-1. Its molecular function is described by: . It is involved in the biological process described with: . 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed in adults stages of both sexes.
FBgn0053474	CG33474	0.266424626	0.386513867	0.999936032	NA	PEX11G	moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG33474 (FBgn0053474). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:10421706..10422989. It has the cytological map location 47A7. Protein features are: Peroxisomal biogenesis factor 11; Peroxisomal membrane protein 11C, metazoa. Its molecular function is unknown. It is involved in the biological process described with: peroxisome fission. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages.  "
FBgn0034498	CG16868	0.266464632	0.525830112	0.999936032	CACHD1	CACHD1;CACNA2D1;CACNA2D2	high;moderate;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG16868 (FBgn0034498). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:20281629..20287094. It has the cytological map location 56F16. Protein features are: Periplasmic sensor domain-like; von Willebrand factor, type A. Its molecular function is described by: . It is involved in the biological process described with: . 6 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, in adult female stages.  "
FBgn0037513	pyd3	0.266464632	0.525830112	0.999936032	UPB1	UPB1	high	NA	NA	NA	"The gene pyd3 is referred to in FlyBase by the symbol Dmel\pyd3 (CG3027, FBgn0037513). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:7747913..7750079. It has the cytological map location 84D14. Protein features are: Carbon-nitrogen hydrolase. Its molecular function is described by: beta-ureidopropionase activity. It is involved in the biological process described with: 'de novo' pyrimidine nucleobase biosynthetic process; pyrimidine nucleobase catabolic process. 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages.  "
FBgn0034223	Tes	0.266531131	0.514650249	0.999936032	TES	TES;LMCD1	high;moderate	NA	NA	NA	"The gene Testin is referred to in FlyBase by the symbol Dmel\Tes (CG6522, FBgn0034223). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:17465879..17469177. It has the cytological map location 54B16. Protein features are: PET domain; PET testin; Zinc finger, LIM-type. Its molecular function is described by: zinc ion binding. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, during early pupal stages, in adult female stages.  "
FBgn0039260	Smg6	0.266569205	0.467822124	0.999936032	NA	SMG6	high	NA	NA	NA	"The gene Smg6 is referred to in FlyBase by the symbol Dmel\Smg6 (CG6369, FBgn0039260). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:25029429..25033465. It has the cytological map location 96B17. Protein features are: DNA/RNA-binding domain, Est1-type; PIN domain; PIN domain-like; Tetratricopeptide-like helical domain. Its molecular function is described by: ribonuclease activity; telomeric DNA binding; telomerase RNA binding; ribonucleoprotein complex binding; endoribonuclease activity. It is involved in the biological process described with: mRNA export from nucleus; regulation of RNA stability; telomere maintenance via telomerase; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; neuromuscular synaptic transmission; synapse organization. 12 alleles are reported. The phenotype of these alleles manifest in: eye. The phenotypic classes of alleles include: lethal; neurophysiology defective; viable; decreased cell number. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages.  "
FBgn0038129	TBC1D5	0.266747611	0.495846661	0.999936032	NA	TBC1D5	high	NA	NA	NA	"The gene TBC1 domain family member 5 is referred to in FlyBase by the symbol Dmel\TBC1D5 (CG8449, FBgn0038129). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:13269137..13272011. It has the cytological map location 87E3. Protein features are: Rab-GTPase-TBC domain. Its molecular function is described by: Rab GTPase binding; GTPase activator activity. It is involved in the biological process described with: activation of GTPase activity; regulation of vesicle fusion; regulation of GTPase activity; intracellular protein transport. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; flight defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed during early pupal stages.  "
FBgn0039152	Root	0.266828741	0.466784399	0.999936032	NA	CROCC;CEP250;CROCC2	high;moderate;moderate	DNA-binding with transcription factor activity	NA	NA	"The gene Rootletin is referred to in FlyBase by the symbol Dmel\Root (CG6129, FBgn0039152). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:24113286..24128193. It has the cytological map location 95E1. Its molecular function is unknown. It is involved in the biological process described with: auditory behavior; mechanosensory behavior; sensory perception of touch; ciliary basal body organization; sensory perception of sound. 25 alleles are reported. The phenotypes of these alleles manifest in: ciliary basal body; centriole; ciliary rootlet. The phenotypic classes of alleles include: grooming behavior defective; locomotor behavior defective; behavior defective; viable; proboscis extension reflex defective; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, in adult male stages.  "
FBgn0032223	GATAd	0.267262051	0.47401557	0.999936032	NA	GATA4;GATA3;GATA1;GATA6;GATA5;GATA2;TRPS1	moderate;low;low;low;low;low;low	DNA-binding with transcription factor activity(GATA)	NA	NA	"The gene GATAd is referred to in FlyBase by the symbol Dmel\GATAd (CG5034, FBgn0032223). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:10333734..10339185. It has the cytological map location 31D9. Protein features are: Zinc finger, AD-type; Zinc finger, GATA-type. Its molecular function is described by: chromatin binding; RNA polymerase II transcription factor binding; zinc ion binding; RNA polymerase II transcription factor activity, sequence-specific DNA binding; transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding; RNA polymerase II regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated; cell differentiation. 11 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic class of alleles includes: visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, in adult female stages.  "
FBgn0259234	Camta	0.267282375	0.508348824	0.999936032	NA	CAMTA2;CAMTA1	high;high	DNA-binding with transcription factor activity(CG-1|TIG)	NA	NA	"The gene Calmodulin-binding transcription activator is referred to in FlyBase by the symbol Dmel\Camta (CG42332, FBgn0259234). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (all unique). Gene sequence location is 2R:9446046..9480076. It has the cytological map location 45D8. Protein features are: Ankyrin repeat-containing domain; Armadillo-like helical; CG-1 DNA-binding domain; IPT domain; IQ motif, EF-hand binding site; Immunoglobulin E-set; Immunoglobulin-like fold; P-loop containing nucleoside triphosphate hydrolase; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: sequence-specific DNA binding; DNA binding; transcription factor activity, sequence-specific DNA binding; transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding; calmodulin binding; protein homodimerization activity. It is involved in the biological process described with: response to light stimulus; positive regulation of transcription, DNA-templated; deactivation of rhodopsin mediated signaling; positive regulation of transcription from RNA polymerase II promoter. 32 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; eye photoreceptor cell. The phenotypic classes of alleles include: behavior defective; viable; increased mortality during development; phenotype; fertile; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during early pupal stages, in stages of adults of both sexes.  "
FBgn0039972	CG17018	0.267561863	0.511294972	0.999936032	NA	KIAA0430	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17018 (FBgn0039972). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is 2L:22308755..22368796. It has the cytological map location 40F7. Protein features are: Marf1, RNA recognition motif 2; Meiosis regulator and mRNA stability factor 1; OST-HTH/LOTUS domain; RNA recognition motif domain. Its molecular function is described by: nucleic acid binding. It is involved in the biological process described with: regulation of gene expression. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0026393	Or43b	0.26759727	0.283851886	0.999936032	NA	NA	NA	NA	transmembrane protein	GPCR	"The gene Odorant receptor 43b is referred to in FlyBase by the symbol Dmel\Or43b (CG17853, FBgn0026393). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:7920835..7922604. It has the cytological map location 43F2. Protein features are: Olfactory receptor, insect. Its molecular function is described by: odorant binding; olfactory receptor activity. It is involved in the biological process described with: sensory perception of smell; detection of chemical stimulus involved in sensory perception of smell. 11 alleles are reported. The phenotype of these alleles manifest in: sensillum basiconicum. The phenotypic classes of alleles include: fertile; smell perception defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed during early pupal stages.  "
FBgn0032973	CG6675	0.26759727	0.283851886	0.999936032	NA	PNLIPRP1;PNLIPRP2;PLA1A;PNLIP;LPL;LIPG;LIPC	low;low;low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6675 (FBgn0032973). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:22108964..22110449. It has the cytological map location 40E3. Protein features are: Alpha/Beta hydrolase fold; Lipase, N-terminal; Lipase/vitellogenin; Triacylglycerol lipase family. Its molecular function is described by: lipase activity; carboxylic ester hydrolase activity. It is involved in the biological process described with: lipid catabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed at stages throughout the pupal period, in adult male stages.  "
FBgn0034095	CG15701	0.26759727	0.283851886	0.999936032	NA	WDR60	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15701 (FBgn0034095). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:16230198..16234087. It has the cytological map location 52F11-53A1. Protein features are: WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: dynein light chain binding; dynein heavy chain binding; ATP-dependent microtubule motor activity, plus-end-directed. It is involved in the biological process described with: outer dynein arm assembly; cilium movement. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of very low expression.  Peak expression observed during late larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0266622	CR45129	0.267631881	0.477873698	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45129 (FBgn0266622). It is a non_protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts. Gene sequence location is 2R:7325896..7335195. It has the cytological map location 43A4-43B1. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available.
FBgn0026263	bip1	0.267999188	0.522180404	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene bip1 is referred to in FlyBase by the symbol Dmel\bip1 (CG7574, FBgn0026263). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:8054333..8058713. It has the cytological map location 66B3. Its molecular function is described by: POZ domain binding. It is involved in the biological process described with: larval lymph gland hemopoiesis. 16 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval lymph gland. The phenotypic classes of alleles include: viable; female fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during early pupal stages.  "
FBgn0026869	Thd1	0.268008841	0.468205701	0.999936032	NA	TDG	high	DNA-binding with transcription factor activity(AT_hook)	NA	NA	"The gene Thd1 is referred to in FlyBase by the symbol Dmel\Thd1 (CG1981, FBgn0026869). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 4:538332..557854. It has the cytological map location 102C4-102C5. Protein features are: AT hook, DNA-binding motif; G/U mismatch-specific DNA glycosylase; Uracil-DNA glycosylase-like. Its molecular function is described by: double-stranded DNA binding; pyrimidine-specific mismatch base pair DNA N-glycosylase activity; uracil DNA N-glycosylase activity. It is involved in the biological process described with: cellular response to DNA damage stimulus; mismatch repair; base-excision repair, AP site formation. 8 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 12-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0026749	Yippee	0.268055436	0.431022051	0.999936032	YPEL5	YPEL5;YPEL1;YPEL4;YPEL2;YPEL3	high;moderate;low;low;low	NA	NA	NA	"The gene Yippee is referred to in FlyBase by the symbol Dmel\Yippee (CG1989, FBgn0026749). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:13385914..13387417. It has the cytological map location 11F1. Protein features are: Yippee domain; Yippee/Mis18/Cereblon. Its molecular function is described by: metal ion binding. It is involved in the biological process described with: . 4 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum. The phenotypic classes of alleles include: visible; viable; body color defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, during early pupal stages.  "
FBgn0005592	btl	0.268126115	0.513405564	0.999936032	NA	FGFR1;FGFR2;FGFR4;FGFR3;RET;PDGFRA	high;moderate;moderate;moderate;low;low	NA	transmembrane protein	NA	NA
FBgn0085261	CG34232	0.268188014	0.420638894	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG34232 (FBgn0085261). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2R:12164909..12165812. It has the cytological map location 48E4. Its molecular function is described by: . It is involved in the biological process described with: . One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0030241	feo	0.268467562	0.417454565	0.999936032	NA	PRC1	high	NA	NA	NA	"The gene fascetto is referred to in FlyBase by the symbol Dmel\feo (CG11207, FBgn0030241). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:10852446..10854869. It has the cytological map location 9F5. Protein features are: Microtubule-associated protein, MAP65/Ase1/PRC1. Its molecular function is described by: microtubule binding. It is involved in the biological process described with: actomyosin contractile ring contraction; epithelium development; germarium-derived egg chamber formation; mitotic spindle organization; mitotic cytokinesis. 31 alleles are reported. The phenotypes of these alleles manifest in: testis; ganglion mother cell; embryonic/larval neuroblast; mesothoracic tergum; spermatocyte; epithelium; female germline cyst; posterior supraalar bristle. The phenotypic classes of alleles include: lethal; phenotype; increased mortality during development; cell lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0038160	CG9759	0.268581196	0.253718994	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG9759 (FBgn0038160). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:13607078..13609246. It has the cytological map location 87F4. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages.
FBgn0085488	CG34459	0.268581196	0.253718994	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG34459 (FBgn0085488). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:16824664..16826648. It has the cytological map location 53D11. Protein features are: Protein of unknown function DUF745. Its molecular function is described by: . It is involved in the biological process described with: developmental process. One allele is reported. No phenotypic data is available. The phenotypic class of allele includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0001970	Pgant35A	0.268949846	0.504714031	0.999936032	NA	GALNT11;GALNTL5;POC1B-GALNT4;GALNT6;GALNT12;GALNT5;GALNT13;GALNT7;GALNT3;GALNT1;GALNTL6;GALNT4;GALNT10	high;moderate;low;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene Polypeptide N-acetylgalactosaminyltransferase 35A is referred to in FlyBase by the symbol Dmel\Pgant35A (CG7480, FBgn0001970). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:14359252..14361411. It has the cytological map location 35A4. Protein features are: Glycosyltransferase 2-like; Nucleotide-diphospho-sugar transferases; Ricin B, lectin domain. Its molecular function is described by: polypeptide N-acetylgalactosaminyltransferase activity. It is involved in the biological process described with: open tracheal system development; oligosaccharide biosynthetic process. 19 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal - all die before end of embryonic stage; lethal; wild-type; some die during embryonic stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, during early pupal stages, in adult female stages.  "
FBgn0020616	SA	0.269346666	0.50670811	0.999936032	NA	STAG1;STAG2;STAG3;STAG3L4	high;moderate;moderate;moderate	NA	NA	NA	"The gene Stromalin is referred to in FlyBase by the symbol Dmel\SA (CG3423, FBgn0020616). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:6950421..6954586. It has the cytological map location 27C7. Protein features are: Armadillo-like helical; Armadillo-type fold; STAG; Stromalin conservative domain. Its molecular function is described by: chromatin binding. It is involved in the biological process described with: synaptonemal complex assembly; neuron remodeling; mitotic sister chromatid cohesion. 9 alleles are reported. The phenotypes of these alleles manifest in: synaptonemal complex; oocyte; chromosome, centromeric region. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; some die during pupal stage; planar polarity defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0033663	ERp60	0.269532864	0.418210144	0.999936032	NA	PDIA3;P4HB;PDIA4	high;low;moderate	NA	NA	NA	"The gene ERp60 is referred to in FlyBase by the symbol Dmel\ERp60 (CG8983, FBgn0033663). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:11887568..11890979. It has the cytological map location 48C5. Protein features are: Disulphide isomerase; Protein disulphide isomerase; Thioredoxin domain; Thioredoxin, conserved site; Thioredoxin-like fold. Its molecular function is described by: protein disulfide isomerase activity. It is involved in the biological process described with: response to endoplasmic reticulum stress; cell redox homeostasis; protein folding. 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0038365	CG9593	0.269702929	0.439624147	0.999936032	NA	ANGPTL4;ANGPTL1;ANGPTL2;ANGPTL6	high;moderate;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9593 (FBgn0038365). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:15802275..15803653. It has the cytological map location 89A5. Protein features are: Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain; Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1; Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2. Its molecular function is described by: transmembrane receptor protein tyrosine kinase activator activity. It is involved in the biological process described with: negative regulation of apoptotic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of very low expression.  Peak expression observed within 00-12 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult male stages.  "
FBgn0263772	CG43689	0.269804941	0.366887103	0.999936032	NA	MYT1L;ST18;MYT1	high;moderate;moderate	DNA-binding with transcription factor activity(zf-C2HC)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG43689 (FBgn0263772). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (all unique). Gene sequence location is X:4075978..4092237. It has the cytological map location 4A5. Protein features are: Myc-type, basic helix-loop-helix (bHLH) domain; WD40/YVTN repeat-like-containing domain; Zinc finger, C2HC-type. Its molecular function is described by: protein dimerization activity; transcription factor activity, sequence-specific DNA binding; zinc ion binding. It is involved in the biological process described with: regulation of transcription, DNA-templated. 8 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; Z disc; sarcomere; myofibril. The phenotypic classes of alleles include: viable; flightless; body color defective."
FBgn0033315	beta3GalTII	0.269983579	0.489726393	0.999936032	B3GALT6	B3GALT6	high	NA	transmembrane protein	NA	"The gene Galactosyltransferase II is referred to in FlyBase by the symbol Dmel\‘_3GalTII (CG8734, FBgn0033315). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:8626181..8627611. It has the cytological map location 44D5. Protein features are: Glycosyl transferase, family 31. Its molecular function is described by: galactosyltransferase activity. It is involved in the biological process described with: protein glycosylation; chondroitin sulfate biosynthetic process; heparan sulfate proteoglycan biosynthetic process; glycosaminoglycan biosynthetic process. 5 alleles are reported. The phenotypes of these alleles manifest in: interommatidial bristle; eye; wing; wing vein. The phenotypic classes of alleles include: visible; viable; lethal; flightless. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0010397	LamC	0.270065107	0.449960365	0.999936032	NA	LMNA;LMNB1;LMNB2;LMNTD1;MIR7108	high;moderate;moderate;moderate;moderate	NA	NA	NA	"The gene Lamin C is referred to in FlyBase by the symbol Dmel\LamC (CG10119, FBgn0010397). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:14570810..14575771. It has the cytological map location 51B1. Protein features are: Intermediate filament protein; Lamin Tail Domain. Its molecular function is described by: structural molecule activity. It is involved in the biological process described with: male meiosis cytokinesis; chromatin silencing; muscle tissue morphogenesis; nuclear pore distribution; regulation of actin filament polymerization; tendon development; chromatin organization. 57 alleles are reported. The phenotypes of these alleles manifest in: nuclear membrane; dorsal medial muscle; sense organ; digestive system; sclerite; anterior-posterior compartment boundary of imaginal disc; nuclear periphery; ventral thoracic disc; A1-7 ventral longitudinal muscle 4; NMJ bouton; salivary gland; membrane-enclosed lumen; tendon cell; macromolecular complex; A band; mitochondrial membrane. The phenotypic classes of alleles include: increased mortality during development; phenotype; some die during prepupal stage; increased mortality; some die during pupal stage; melanotic mass phenotype; size defective; behavior defective; partially lethal - majority die; suppressor of variegation; increased cell death. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages.  "
FBgn0002906	Blm	0.270130053	0.502211933	0.999936032	NA	BLM;RECQL;RECQL5;WRN	high;moderate;low;moderate	NA	NA	NA	"The gene Bloom syndrome helicase is referred to in FlyBase by the symbol Dmel\Blm (CG6920, FBgn0002906). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:11736810..11741783. It has the cytological map location 86E17. Protein features are: ATP-dependent DNA helicase RecQ, zinc-binding domain; DEAD/DEAH box helicase domain; DNA helicase, ATP-dependent, RecQ type; DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site; HRDC domain; HRDC-like; Helicase superfamily 1/2, ATP-binding domain; Helicase, C-terminal; P-loop containing nucleoside triphosphate hydrolase; RQC domain; Winged helix-turn-helix DNA-binding domain. Its molecular function is described by: ATP-dependent 3'-5' DNA helicase activity; four-way junction helicase activity; Y-form DNA binding; DNA helicase activity; ATP binding; ATP-dependent DNA helicase activity; helicase activity; DNA-dependent ATPase activity. It is involved in the biological process described with 14 unique terms, many of which group under: DNA conformation change; regulation of biological process; DNA duplex unwinding; non-recombinational repair; double-strand break repair via synthesis-dependent strand annealing; biological regulation; negative regulation of macromolecule metabolic process; nucleobase-containing compound biosynthetic process; macromolecule biosynthetic process; cellular nitrogen compound biosynthetic process. 17 alleles are reported. The phenotypes of these alleles manifest in: testis; embryo; adult gut; wing disc; ovary. The phenotypic classes of alleles include: increased mortality during development; phenotype; increased mortality; sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0016697	Prosalpha5	0.270392599	0.42114403	0.999936032	PSMA5	PSMA5	high	NA	NA	NA	"The gene Proteasome ‘±5 subunit is referred to in FlyBase by the symbol Dmel\Pros‘±5 (CG10938, FBgn0016697). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:17412767..17413769. It has the cytological map location 54B7. Protein features are: Nucleophile aminohydrolases, N-terminal; Proteasome alpha-subunit, N-terminal domain; Proteasome alpha-type subunit; Proteasome subunit alpha5; Proteasome, subunit alpha/beta. Its molecular function is described by: endopeptidase activity; threonine-type endopeptidase activity. It is involved in the biological process described with: proteasome-mediated ubiquitin-dependent protein catabolic process. 8 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0086251	del	0.270458499	0.497707646	0.999936032	NA	NA	NA	NA	NA	NA	"The gene deadlock is referred to in FlyBase by the symbol Dmel\del (CG9252, FBgn0086251). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:21145137..21148546. It has the cytological map location 38A6-38E9. Its molecular function is described by: . It is involved in the biological process described with: piRNA metabolic process; oocyte localization involved in germarium-derived egg chamber formation; karyosome formation; oogenesis; mitotic spindle organization; germarium-derived egg chamber formation; oocyte development; fusome organization. 13 alleles are reported. The phenotypes of these alleles manifest in: karyosome; egg; dorsal appendage. The phenotypic classes of alleles include: female sterile; mitotic cell cycle defective; viable; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0029882	CG3226	0.270493903	0.439622173	0.999936032	CACYBP	CACYBP	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3226 (FBgn0029882). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:6653113..6654248. It has the cytological map location 6C3. Protein features are: CS domain; HSP20-like chaperone; SGS domain; Siah interacting protein, N-terminal. Its molecular function is unknown. It is involved in the biological process described with: heart development. 9 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0002069	AspRS	0.270543845	0.415219776	0.999936032	NA	DARS	high	NA	NA	NA	"The gene Aspartyl-tRNA synthetase is referred to in FlyBase by the symbol Dmel\AspRS (CG3821, FBgn0002069). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:12877004..12883168. It has the cytological map location 49D6-49D7. Protein features are: Aminoacyl-tRNA synthetase, class II; Aminoacyl-tRNA synthetase, class II (D/K/N); Aspartate-tRNA synthetase, type 2; Aspartyl/Asparaginyl-tRNA synthetase, class IIb; Nucleic acid-binding, OB-fold; OB-fold nucleic acid binding domain, AA-tRNA synthetase-type. Its molecular function is described by: nucleic acid binding; ATP binding; aspartate-tRNA ligase activity. It is involved in the biological process described with: aspartyl-tRNA aminoacylation; growth. 20 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; embryonic/larval neuroblast; wing; wing disc. The phenotypic classes of alleles include: mitotic cell cycle defective; phenotype; lethal - all die during P-stage; viable; some die during P-stage; increased mortality; lethal - all die before end of larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed during late larval stages, at stages throughout the pupal period.  "
FBgn0051174	CG31174	0.270593088	0.455994163	0.999936032	NA	DCTN3	low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31174 (FBgn0051174). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:21868681..21869514. It has the cytological map location 93F14. Its molecular function is described by: . It is involved in the biological process described with: . 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed during late larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0035120	wac	0.270635177	0.505390204	0.999936032	NA	NA	NA	NA	NA	NA	"The gene wee Augmin is referred to in FlyBase by the symbol Dmel\wac (CG13879, FBgn0035120). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:258176..259097. It has the cytological map location 61B3. Its molecular function is described by: microtubule binding; protein binding. It is involved in the biological process described with: spindle assembly involved in female meiosis; cell division; female meiotic nuclear division; spindle assembly. 10 alleles are reported. The phenotypes of these alleles manifest in: adult cuticle; spindle; meiotic spindle; oocyte; eye; chromosome; macrochaeta; spindle pole. The phenotypic classes of alleles include: female sterile; viable; mitotic cell cycle defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0263852	Dad1	0.270666498	0.431439816	0.999936032	NA	DAD1	high	NA	transmembrane protein	NA	"The gene Defender against apoptotic cell death 1 is referred to in FlyBase by the symbol Dmel\Dad1 (CG13393, FBgn0263852). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:8383612..8384137. It has the cytological map location 29C1-29C2. Protein features are: DAD/Ost2. Its molecular function is described by: oligosaccharyl transferase activity; dolichyl-diphosphooligosaccharide-protein glycotransferase activity. It is involved in the biological process described with: protein N-linked glycosylation. 7 alleles are reported. The phenotypes of these alleles manifest in: eye; wing disc; wing. The phenotypic classes of alleles include: phenotype; increased mortality during development; lethal; increased mortality."
FBgn0053109	CG33109	0.27074136	0.308654075	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG33109 (FBgn0053109). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:14220560..14221584. It has the cytological map location 88A12. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed in adult female stages.
FBgn0035475	CG10866	0.270935833	0.485033576	0.999936032	C5orf28	TMEM267	high	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG10866 (FBgn0035475). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:3936060..3937992. It has the cytological map location 64A1. Protein features are: Transmembrane protein 267. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0025839	ND-B14.5A	0.270973523	0.420723771	0.999936032	NA	NDUFA7	high	NA	NA	NA	"The gene NADH dehydrogenase (ubiquinone) B14.5 A subunit is referred to in FlyBase by the symbol Dmel\ND-B14.5A (CG3621, FBgn0025839). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:2172526..2173432. It has the cytological map location 2D6-2E1. Protein features are: NADH:ubiquinone oxidoreductase subunit B14.5a. Its molecular function is described by: NADH dehydrogenase activity; NADH dehydrogenase (ubiquinone) activity. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone. 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0028411	Nxt1	0.271326321	0.451134835	0.999936032	NXT1	NXT1;NXT2	high;moderate	NA	NA	NA	"The gene NTF2-related export protein 1 is referred to in FlyBase by the symbol Dmel\Nxt1 (CG12752, FBgn0028411). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:23811321..23811974. It has the cytological map location 60A2. Protein features are: NTF2-like domain; Nuclear transport factor 2; Nuclear transport factor 2, eukaryote. Its molecular function is unknown. It is involved in the biological process described with: poly(A)+ mRNA export from nucleus; negative regulation of innate immune response; defense response to Gram-negative bacterium; cellular response to starvation. 9 alleles are reported. The phenotypes of these alleles manifest in: Z disc; sarcomere; mesothoracic tergum. The phenotypic classes of alleles include: visible; viable; lethal - all die during larval stage; lethal - all die before end of pupal stage; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0035761	RhoGEF4	0.271336174	0.468330871	0.999936032	ARHGEF39	FGD3;ARHGEF39;FGD2;FGD4;FGD1	high;high;moderate;moderate;moderate	NA	NA	NA	"The gene Rho guanine nucleotide exchange factor 4 is referred to in FlyBase by the symbol Dmel\RhoGEF4 (CG8606, FBgn0035761). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:7321099..7323411. It has the cytological map location 65F4. Protein features are: Dbl homology (DH) domain; PH domain-like; Pleckstrin homology domain. Its molecular function is described by: Rho guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: positive regulation of Rho protein signal transduction; positive regulation of stress fiber assembly. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0028476	Usp1	0.271387374	0.444183522	0.999936032	NA	USP1	high	NA	NA	NA	"The gene Ubiquitin specific protease 1 is referred to in FlyBase by the symbol Dmel\Usp1 (CG15817, FBgn0028476). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:29229161..29235302. It has the cytological map location 99A1. Protein features are: Peptidase C19, ubiquitin carboxyl-terminal hydrolase; Ubiquitin specific peptidase 1; Ubiquitin specific protease domain; Ubiquitin specific protease, conserved site. Its molecular function is described by: cysteine-type endopeptidase activity; thiol-dependent ubiquitin-specific protease activity. It is involved in the biological process described with: regulation of DNA repair; ubiquitin-dependent protein catabolic process; protein deubiquitination. 6 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: locomotor behavior defective; fertile; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0030268	Klp10A	0.271512369	0.463543527	0.999936032	NA	KIF2A;KIF2B;KIF2C;KIF24	high;moderate;moderate;moderate	NA	NA	NA	"The gene Kinesin-like protein at 10A is referred to in FlyBase by the symbol Dmel\Klp10A (CG1453, FBgn0030268). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (1 unique). Gene sequence location is X:11129362..11137118. It has the cytological map location 10A6. Protein features are: Kinesin motor domain; Kinesin motor domain, conserved site; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: motor activity; ATP binding; ATP-dependent microtubule motor activity, plus-end-directed; microtubule binding. It is involved in the biological process described with 11 unique terms, many of which group under: cellular component assembly; establishment of cell polarity; cell differentiation; spindle assembly; centriole assembly; protein localization; establishment of meiotic spindle orientation; microtubule cytoskeleton organization involved in mitosis; mitotic sister chromatid segregation; asymmetric protein localization. 14 alleles are reported. The phenotypes of these alleles manifest in: male germline stem cell; trichogen cell; spermatogonium; primary spermatocyte; centriole; spindle; wing disc; meiotic spindle. The phenotypic classes of alleles include: phenotype; increased mortality during development; increased mortality; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0032645	CG15142	0.27192433	0.477863871	0.999936032	NA	CDK2AP1;CDK2AP2	moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15142 (FBgn0032645). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:17497994..17498821. It has the cytological map location 36C10. Protein features are: Cyclin-dependent kinase 2-associated protein 1/2. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed during early pupal stages, in adult male stages.  "
FBgn0015524	otp	0.272345867	0.401566478	0.999936032	NA	OTP	high	DNA-binding with transcription factor activity(Homeobox)	NA	NA	"The gene orthopedia is referred to in FlyBase by the symbol Dmel\otp (CG10036, FBgn0015524). It is a protein_coding_gene from Drosophila melanogaster. It has 8 annotated transcripts and 8 polypeptides (all unique). Gene sequence location is 2R:20883625..20903414. It has the cytological map location 57B4. Protein features are: Helix-turn-helix motif; Homeobox domain; Homeobox domain-like; Homeobox, conserved site; OAR domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: DNA binding; sequence-specific DNA binding. It is involved in the biological process described with: lateral inhibition; regulation of transcription, DNA-templated. 5 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; wing; chaeta. The phenotypic classes of alleles include: partially lethal; body color defective; lethal; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0034493	CG8908	0.272345867	0.401566478	0.999936032	NA	ABCA3;ABCA1;ABCA7;ABCA5;ABCA10;ABCA6;ABCA8;ABCA9;ABCA12;ABCA2;ABCA4;ABCA13	moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8908 (FBgn0034493). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:20264920..20270994. It has the cytological map location 56F11. Protein features are: AAA+ ATPase domain; ABC transporter A, ABCA; ABC transporter-like; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: ATP binding; ATPase activity, coupled to transmembrane movement of substances. It is involved in the biological process described with: transport; lipid transport. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0263663	CR43654	0.272345867	0.401566478	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR43654 (FBgn0263663). It is a non_protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts. Gene sequence location is 3R:22777567..22781465. It has the cytological map location 94C6. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0264855	AP-2alpha	0.272351102	0.474757841	0.999936032	NA	AP2A2;AP2A1	high;moderate	NA	NA	NA	"The gene Adaptor Protein complex 2, ‘± subunit is referred to in FlyBase by the symbol Dmel\AP-2‘± (CG4260, FBgn0264855). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:408030..414777. It has the cytological map location 21C2. Protein features are: Adaptor protein complex AP-2, alpha subunit; Armadillo-like helical; Armadillo-type fold; Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain; Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain; Clathrin/coatomer adaptor, adaptin-like, N-terminal; Coatomer/calthrin adaptor appendage, C-terminal subdomain; Coatomer/clathrin adaptor appendage, Ig-like subdomain. Its molecular function is described by: protein transporter activity. It is involved in the biological process described with 11 unique terms, many of which group under: protein transport; cell division; protein localization; single-organism transport; cellular localization; anatomical structure development; peptide transport; gamete generation; regulation of biological process; establishment of localization in cell; positive regulation of transport; cell cycle process. 28 alleles are reported. The phenotypes of these alleles manifest in: cell projection; late embryo; plasma membrane bounded cell projection; nerve; synapse; neuron part; blastoderm embryo; cell part; imaginal disc; adipose system; cell component; histaminergic neuron. The phenotypic classes of alleles include: lethal - all die before end of embryonic stage; phenotype; lethal - all die before end of P-stage; behavior defective."
FBgn0031995	CG8475	0.272412823	0.449656508	0.999936032	PHKB	PHKB	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8475 (FBgn0031995). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 2L:8190808..8196918. It has the cytological map location 28F1. Protein features are: Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family; Phosphorylase kinase alpha/beta subunit; Six-hairpin glycosidase-like. Its molecular function is described by: phosphorylase kinase activity; calmodulin binding. It is involved in the biological process described with: glycogen metabolic process. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0003751	trk	0.272445798	0.485285986	0.999936032	NA	NA	NA	NA	NA	NA	"The gene trunk is referred to in FlyBase by the symbol Dmel\trk (CG5619, FBgn0003751). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:10271443..10272324. It has the cytological map location 31B1. Protein features are: Cystine-knot cytokine. Its molecular function is described by: torso binding. It is involved in the biological process described with: maternal determination of anterior/posterior axis, embryo; torso signaling pathway; anterior/posterior axis specification, embryo; terminal region determination. 44 alleles are reported. The phenotypes of these alleles manifest in: larval abdominal segment 8; basiproboscis; posterior endoderm; larval head; adult integumentary system; embryonic/larval tracheal system; epithelial furrow; stage 6 embryo; primordium; procephalic segment; late extended germ band embryo; adult head segment. The phenotypic classes of alleles include: phenotype; viable; increased mortality during development; visible; lethal - all die before end of P-stage; embryonic/larval segmentation phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0039801	Npc2h	0.272445798	0.485285986	0.999936032	NA	NPC2	moderate	NA	NA	NA	"The gene Niemann-Pick type C-2h is referred to in FlyBase by the symbol Dmel\Npc2h (CG11315, FBgn0039801). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:30745479..30746290. It has the cytological map location 100A3. Protein features are: Immunoglobulin E-set; MD-2-related lipid-recognition domain; ML domain, Npc2 like. Its molecular function is described by: lipid antigen binding; lipoteichoic acid binding; peptidoglycan binding; lipopolysaccharide binding; sterol binding. It is involved in the biological process described with: sterol transport; hemolymph coagulation; intracellular cholesterol transport. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed in adult male stages.  "
FBgn0085360	CG34331	0.272650231	0.346080967	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG34331 (FBgn0085360). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:20122453..20125271. It has the cytological map location 19B1. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: viable; body color defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during early pupal stages.
FBgn0029867	CG3847	0.27331777	0.460173046	0.999936032	NA	NA	NA	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3847 (FBgn0029867). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:6347103..6349236. It has the cytological map location 5F2. Protein features are: Zinc finger C2H2-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: nucleic acid binding. The biological processes in which it is involved are not known. 8 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: lethal; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0035238	CG12104	0.273560827	0.463156919	0.999936032	NA	TOX4;TOX2;TOX;TOX3	high;high;high;moderate	DNA-binding with transcription factor activity(HMG_box)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12104 (FBgn0035238). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:1600726..1602674. It has the cytological map location 62A7. Protein features are: High mobility group box domain. Its molecular function is described by: . It is involved in the biological process described with: . 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0037446	Zif	0.273621272	0.473690992	0.999936032	NA	ZNF200;ZNF233;ZNF28;ZNF492;ZNF570;RBAK-RBAKDN;ZNF560;LOC730110;ZNF527;ZFP28;ZNF485;ZNF792;ZNF117;ZNF675;ZNF816;ZNF681;ZNF43;ZNF480;ZNF98;ZNF888;ZNF568;ZNF761;ZNF850;ZNF558;ZNF845;ZNF611;ZSCAN30;ZNF595;ZNF211;ZNF732;ZNF721;ZNF730;ZNF468	low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene Zinc-finger protein is referred to in FlyBase by the symbol Dmel\Zif (CG10267, FBgn0037446). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:6457088..6458822. It has the cytological map location 83E8. Protein features are: Zinc finger C2H2-type; Zinc finger, AD-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: DNA binding; zinc ion binding. It is involved in the biological process described with: larval lymph gland hemopoiesis; establishment or maintenance of neuroblast polarity; neuroblast proliferation. 11 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval lymph gland; wing; neuroblast. The phenotypic classes of alleles include: lethal; lethal - all die before end of prepupal stage; increased mortality during development; viable; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0031603	CG15432	0.273650889	0.493803165	0.999936032	NA	FAM32A	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15432 (FBgn0031603). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:4442320..4442985. It has the cytological map location 24F2. Protein features are: Protein of unknown function DUF1754, eukaryotic. Its molecular function is described by: RNA binding. It is involved in the biological process described with: . 6 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: fertile; viable; visible; partially lethal - majority die; some die during pupal stage; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0039800	Npc2g	0.273650889	0.493803165	0.999936032	NA	NPC2	moderate	NA	NA	NA	"The gene Niemann-Pick type C-2g is referred to in FlyBase by the symbol Dmel\Npc2g (CG11314, FBgn0039800). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:30744605..30745263. It has the cytological map location 100A3. Protein features are: Immunoglobulin E-set; MD-2-related lipid-recognition domain; ML domain, Npc2 like. Its molecular function is described by: sterol binding. It is involved in the biological process described with: hemolymph coagulation; intracellular cholesterol transport; mesoderm development; sterol transport. 6 alleles are reported. The phenotype of these alleles manifest in: myofibril. The phenotypic classes of alleles include: viable; flightless. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0050000	GstT1	0.27392135	0.430671962	0.999936032	NA	GSTT2B;GSTT2;GSTT1	high;moderate;moderate	NA	NA	NA	"The gene Glutathione S transferase T1 is referred to in FlyBase by the symbol Dmel\GstT1 (CG30000, FBgn0050000). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:9605988..9607184. It has the cytological map location 45F6. Protein features are: Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Thioredoxin-like fold. Its molecular function is described by: glutathione transferase activity. It is involved in the biological process described with: glutathione metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.  "
FBgn0034050	bug	0.273924947	0.456970789	0.999936032	NA	TXNDC15	high	NA	transmembrane protein	NA	"The gene bunker gear is referred to in FlyBase by the symbol Dmel\bug (CG8297, FBgn0034050). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:15934825..15935938. It has the cytological map location 52D2. Protein features are: Thioredoxin-like fold. Its molecular function is unknown. It is involved in the biological process described with: detection of temperature stimulus involved in sensory perception of pain. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; heat stress response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0004242	Syt1	0.273947335	0.514099199	0.999936032	NA	SYT1;SYT2;SYT5;SYT8	high;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene Synaptotagmin 1 is referred to in FlyBase by the symbol Dmel\Syt1 (CG3139, FBgn0004242). It is a protein_coding_gene from Drosophila melanogaster. It has 8 annotated transcripts and 8 polypeptides (6 unique). Gene sequence location is 2L:2772327..2799979. It has the cytological map location 23A6-23B1. Protein features are: C2 domain; Synaptotagmin; Synaptotagmin 1/2. Its molecular function is described by: SNARE binding; protein homodimerization activity; calcium ion binding; clathrin binding; syntaxin binding; protein binding; calcium-dependent phospholipid binding; phosphatidylserine binding. It is involved in the biological process described with 13 unique terms, many of which group under: single-organism behavior; germ cell development; regulation of synapse structure or activity; single-organism organelle organization; single organism reproductive process; regulation of multicellular organismal process; larval locomotory behavior; positive regulation of transport; tripartite regional subdivision; synaptic vesicle endocytosis; behavior. 83 alleles are reported. The phenotypes of these alleles manifest in: neuromuscular junction; egg; bouton; wing; embryonic/larval neuromuscular junction; synaptic vesicle; eye; synapse; crystal cell; neuron. The phenotypic classes of alleles include: locomotor behavior defective; increased mortality; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0039647	jus	0.273947335	0.514099199	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14509 (FBgn0039647). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 3R:29171191..29194994. It has the cytological map location 98F13-99A1. Its molecular function is unknown. It is involved in the biological process described with: olfactory behavior; regulation of membrane potential; mechanosensory behavior; response to mechanical stimulus. 14 alleles are reported. The phenotypes of these alleles manifest in: hub cell; aCC neuron; cyst progenitor cell; RP2 motor neuron; male germline stem cell. The phenotypic classes of alleles include: paralytic; neurophysiology defective; smell perception defective; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages.  "
FBgn0266705	CR45195	0.274008044	0.302454305	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45195 (FBgn0266705). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3R:10876834..10877783. It has the cytological map location 86C7. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0033792	CG13325	0.274428586	0.306768543	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13325 (FBgn0033792). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2R:13110769..13126014. It has the cytological map location 49F2. Protein features are: Acyltransferase 3; Nose resistant-to-fluoxetine protein, N-terminal. Its molecular function is described by: transferase activity, transferring acyl groups other than amino-acyl groups. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed in adult female stages.  "
FBgn0032105	borr	0.274456456	0.444657631	0.999936032	NA	CDCA8	high	NA	NA	NA	"The gene borealin-related is referred to in FlyBase by the symbol Dmel\borr (CG4454, FBgn0032105). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:9251472..9253118. It has the cytological map location 30A6. Protein features are: Cell division protein borealin. Its molecular function is described by: DNA binding; protein binding. It is involved in the biological process described with: mitotic sister chromatid segregation; mitotic cytokinesis; protein localization; histone phosphorylation; mitotic cell cycle, embryonic. 6 alleles are reported. The phenotypes of these alleles manifest in: wing hair; eye; leg; trichogen cell; wing margin bristle; chromatin; spindle; mesothoracic tergum; nucleus; wing. The phenotypic classes of alleles include: partially lethal; cell size defective; phenotype; viable; increased mortality during development; mitotic cell cycle defective; visible; developmental rate defective; some die during P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0001255	ImpE3	0.274460511	0.324310266	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Ecdysone-inducible gene E3 is referred to in FlyBase by the symbol Dmel\ImpE3 (CG2723, FBgn0001255). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:8028453..8029546. It has the cytological map location 84E8-84E9. Its molecular function is unknown. It is involved in the biological process described with: imaginal disc eversion. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during early pupal stages.  "
FBgn0035508	CG15005	0.274460511	0.324310266	0.999936032	NA	MAGEC1	low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15005 (FBgn0035508). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:4200825..4204339. It has the cytological map location 64A10. Protein features are: Mucin-like domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die during embryonic stage; lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 12-18 embryonic stages, during late pupal stages.  "
FBgn0040351	CG11638	0.274460511	0.324310266	0.999936032	NA	CABP4;CABP5;CABP1;CABP2	high;high;high;high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11638 (FBgn0040351). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:1013984..1026703. It has the cytological map location 1E1. Protein features are: EF-Hand 1, calcium-binding site; EF-hand domain; EF-hand domain pair. Its molecular function is described by: calcium ion binding. It is involved in the biological process described with: sensory perception of pain. 16 alleles are reported. The phenotypes of these alleles manifest in: Z disc; sarcomere. The phenotypic classes of alleles include: lethal - all die during larval stage; viable; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0051202	alpha-Man-Ic	0.274460511	0.324310266	0.999936032	NA	MAN1A2;MAN1C1;MAN1A1	moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene ‘±-Mannosidase class I c is referred to in FlyBase by the symbol Dmel\‘±-Man-Ic (CG31202, FBgn0051202). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:29928701..29930386. It has the cytological map location 99C7. Protein features are: Glycoside hydrolase family 47. Its molecular function is described by: calcium ion binding; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. It is involved in the biological process described with: N-glycan processing. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed in adults stages of both sexes.  "
FBgn0026718	fu12	0.274471457	0.426652359	0.999936032	NA	AGPAT2;AGPAT1	moderate;moderate	NA	transmembrane protein	NA	"The gene fu12 is referred to in FlyBase by the symbol Dmel\fu12 (CG17608, FBgn0026718). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2L:8449691..8463994. It has the cytological map location 29C5-29D1. Protein features are: 1-acyl-sn-glycerol-3-phosphate acyltransferase; Phospholipid/glycerol acyltransferase. Its molecular function is described by: acylglycerol O-acyltransferase activity; 1-acylglycerol-3-phosphate O-acyltransferase activity. It is involved in the biological process described with: phospholipid biosynthetic process; behavioral response to ethanol. 11 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: chemical resistant; hyperactive; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during early pupal stages.  "
FBgn0053087	LRP1	0.274477835	0.513698139	0.999936032	NA	LRP1;LRP1B;LRP2;LRP4	high;moderate;low;low	NA	transmembrane protein	NA	"The gene LDL receptor protein 1 is referred to in FlyBase by the symbol Dmel\LRP1 (CG33087, FBgn0053087). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:8174165..8226438. It has the cytological map location 44B8-44C2. Protein features are: EGF-like calcium-binding domain; EGF-like calcium-binding, conserved site; EGF-like domain; EGF-like, conserved site; EGF-type aspartate/asparagine hydroxylation site; Growth factor receptor cysteine-rich domain; LDLR class B repeat; Low-density lipoprotein (LDL) receptor class A repeat; Low-density lipoprotein (LDL) receptor class A, conserved site; Six-bladed beta-propeller, TolB-like. Its molecular function is described by: calcium ion binding. The biological processes in which it is involved are not known. 15 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0261341	verm	0.274801896	0.50623833	0.999936032	NA	NA	NA	NA	NA	NA	"The gene vermiform is referred to in FlyBase by the symbol Dmel\verm (CG8756, FBgn0261341). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3L:19690033..19695260. It has the cytological map location 76C1-76C3. Protein features are: Chitin binding domain; Glycoside hydrolase/deacetylase, beta/alpha-barrel; Low-density lipoprotein (LDL) receptor class A repeat; Low-density lipoprotein (LDL) receptor class A, conserved site. Its molecular function is described by: chitin binding; chitinase activity; chitin deacetylase activity. It is involved in the biological process described with: chitin catabolic process; trachea morphogenesis; dorsal trunk growth, open tracheal system; visual behavior; open tracheal system development; regulation of tube length, open tracheal system; carbohydrate metabolic process. 13 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval dorsal trunk; cuticle; tracheal branch primordium; embryonic/first instar larval cuticle; dorsal trunk primordium; embryonic/larval trachea; embryonic/larval tracheal system. The phenotypic classes of alleles include: some die during pupal stage; lethal - all die before end of pupal stage; some die during embryonic stage; visual behavior defective; viable; lethal - all die before end of embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period.  "
FBgn0264002	MsR2	0.275107319	0.458397217	0.999936032	NA	GPR139;GPR142	moderate;high	NA	transmembrane protein	GPCR	"The gene Myosuppressin receptor 2 is referred to in FlyBase by the symbol Dmel\MsR2 (CG43745, FBgn0264002). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:2282883..2300944. It has the cytological map location 62D5. Protein features are: 7TM GPCR, serpentine receptor class w (Srw); G protein-coupled receptor, rhodopsin-like; GPCR, rhodopsin-like, 7TM. Its molecular function is described by: G-protein coupled receptor activity; neuropeptide receptor activity; myosuppressin receptor activity. It is involved in the biological process described with: G-protein coupled receptor signaling pathway; adult locomotory behavior; adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; behavioral defense response; larval locomotory behavior; neuropeptide signaling pathway. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable."
FBgn0002609	E(spl)m3-HLH	0.275248252	0.478924892	0.999936032	NA	HES6;HES1;HES4;BHLHE41;HES2;BHLHE40	high;low;low;moderate;low;moderate	DNA-binding with transcription factor activity(HLH)	NA	NA	"The gene Enhancer of split m3, helix-loop-helix is referred to in FlyBase by the symbol Dmel\E(spl)m3-HLH (CG8346, FBgn0002609). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:26021823..26023127. It has the cytological map location 96F10. Protein features are: Myc-type, basic helix-loop-helix (bHLH) domain; Orange domain. Its molecular function is described by: sequence-specific DNA binding; protein dimerization activity; transcription factor activity, sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated; regulation of glucose metabolic process; compound eye development. 10 alleles are reported. The phenotypes of these alleles manifest in: wing; scutellar bristle. The phenotypic classes of alleles include: some die during pupal stage; lethal - all die before end of pupal stage; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0051728	l(2)k05911	0.275386098	0.508608113	0.999936032	NA	CTRB1	high	NA	NA	NA	NA
FBgn0261068	LSm7	0.275675917	0.433078419	0.999936032	NA	LSM7	high	NA	NA	NA	"The gene Like Sm 7 is referred to in FlyBase by the symbol Dmel\LSm7 (CG13277, FBgn0261068). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:16742315..16743100. It has the cytological map location 36A14. Protein features are: LSM domain; LSM domain, eukaryotic/archaea-type; Sm-like protein Lsm7. Its molecular function is described by: RNA binding. It is involved in the biological process described with: RNA processing; nuclear-transcribed mRNA catabolic process; mRNA splicing, via spliceosome. 3 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: lethal; increased mortality; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.  "
FBgn0032961	CG1416	0.275908403	0.427384633	0.999936032	AHSA1	AHSA1;AHSA2	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1416 (FBgn0032961). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:21758010..21761000. It has the cytological map location 40A2. Protein features are: Activator of Hsp90 ATPase homologue 1-like; Activator of Hsp90 ATPase, N-terminal; START-like domain. Its molecular function is described by: chaperone binding; ATPase activator activity. It is involved in the biological process described with: response to stress. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0025574	Pli	0.276041198	0.461849871	0.999936032	PELI2	PELI2;PELI1;PELI3	high;high;moderate	NA	NA	NA	"The gene Pellino is referred to in FlyBase by the symbol Dmel\Pli (CG5212, FBgn0025574). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:23860162..23890052. It has the cytological map location 95C5-95C8. Protein features are: Pellino family; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: kinase regulator activity; ubiquitin protein ligase activity. It is involved in the biological process described with: regulation of phosphorylation; positive regulation of protein K48-linked ubiquitination; negative regulation of antimicrobial humoral response; negative regulation of Toll signaling pathway; Toll signaling pathway. 22 alleles are reported. The phenotypes of these alleles manifest in: embryonic head; germ band. The phenotypic classes of alleles include: viable; lethal - all die during larval stage; some die during P-stage; immune response defective; lethal - all die before end of P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0034996	CG13575	0.276140961	0.384708315	0.999936032	NA	TACR1;TACR2;TACR3	low;low;low	NA	transmembrane protein	GPCR	"This gene is referred to in FlyBase by the symbol Dmel\CG13575 (FBgn0034996). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:24255327..24257414. It has the cytological map location 60C4. Protein features are: G protein-coupled receptor, rhodopsin-like; GPCR, rhodopsin-like, 7TM. Its molecular function is described by: G-protein coupled peptide receptor activity; neuropeptide receptor activity; G-protein coupled receptor activity. It is involved in the biological process described with: G-protein coupled receptor signaling pathway. 4 alleles are reported. The phenotype of these alleles manifest in: chaeta. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed during early pupal stages.  "
FBgn0036939	CG7365	0.276140961	0.384708315	0.999936032	NA	PLB1	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7365 (FBgn0036939). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:20124298..20127381. It has the cytological map location 76F2. Protein features are: GDSL lipase/esterase; Phospholipase B; SGNH hydrolase-type esterase domain. Its molecular function is described by: hydrolase activity, acting on ester bonds. It is involved in the biological process described with: phagocytosis. 4 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; flight defective; viable; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages.  "
FBgn0250824	CG33655	0.276140961	0.384708315	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG33655 (FBgn0250824). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:21317793..21320017. It has the cytological map location 57D11. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed in adult male stages.
FBgn0030701	CG16952	0.276153494	0.509293805	0.999936032	NA	BTBD7	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG16952 (FBgn0030701). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (2 unique). Gene sequence location is X:15870183..15875607. It has the cytological map location 13F17. Protein features are: BTB/Kelch-associated; BTB/POZ domain; SKP1/BTB/POZ domain. Its molecular function is described by: . It is involved in the biological process described with: . 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0086908	egg	0.276153494	0.509293805	0.999936032	NA	SETDB1;SETDB2	high;moderate	DNA-binding with transcription factor activity	NA	NA	"The gene eggless is referred to in FlyBase by the symbol Dmel\egg (CG12196, FBgn0086908). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:24775534..24779901. It has the cytological map location 60E1. Protein features are: DNA-binding domain; Methyl-CpG DNA binding; Post-SET domain; Pre-SET domain; SET domain. Its molecular function is described by: double-stranded methylated DNA binding; protein binding; histone-lysine N-methyltransferase activity; zinc ion binding; histone methyltransferase activity (H3-K9 specific). It is involved in the biological process described with: negative regulation of transcription, DNA-templated; regulation of gene expression, epigenetic; positive regulation of methylation-dependent chromatin silencing; female germ-line stem cell asymmetric division; negative regulation of transcription involved in meiotic cell cycle; oogenesis; DNA hypermethylation; regulation of gene silencing; negative regulation of gene expression, epigenetic; histone H3-K9 methylation. 42 alleles are reported. The phenotypes of these alleles manifest in: organelle; intracellular organelle; intracellular; acellular anatomical structure; ommatidium; eye disc posterior to the morphogenetic furrow; cell part; chorion; tergum; egg. The phenotypic classes of alleles include: visible; phenotype; increased mortality during development; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0031571	bark	0.276305958	0.481808317	0.999936032	NA	LOXL3	moderate	NA	transmembrane protein	NA	"The gene bark beetle is referred to in FlyBase by the symbol Dmel\bark (CG3921, FBgn0031571). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:3787167..3802726. It has the cytological map location 24C4-24C5. Protein features are: C-type lectin fold; C-type lectin-like/link domain; CUB domain; P22 tailspike C-terminal domain-like; Parallel beta-helix repeat; Pectin lyase fold; Pectin lyase fold/virulence factor; SRCR domain; SRCR-like domain. Its molecular function is described by: carbohydrate binding; scavenger receptor activity. It is involved in the biological process described with: response to endoplasmic reticulum stress; regulation of tube length, open tracheal system; establishment of endothelial intestinal barrier; cell-cell junction maintenance; tricellular tight junction assembly; liquid clearance, open tracheal system. 21 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval tracheal system; embryonic/larval trachea; septate junction; tricellular tight junction. The phenotypic classes of alleles include: viable; lethal; cell adhesion defective; lethal - all die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 12-18 embryonic stages.  "
FBgn0051549	CG31549	0.276502928	0.416809854	0.999936032	NA	HSD17B14;HSD17B8;CBR4	moderate;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31549 (FBgn0051549). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:5632192..5633321. It has the cytological map location 83B7. Protein features are: NAD(P)-binding domain; Short-chain dehydrogenase/reductase SDR; Short-chain dehydrogenase/reductase, conserved site. Its molecular function is described by: oxidoreductase activity. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 12-18 hour embryonic stages, in stages of adults of both sexes.  "
FBgn0266722	Trs33	0.276573128	0.474372421	0.999936032	NA	TRAPPC6B;TRAPPC6A	high;moderate	NA	NA	NA	"The gene TRAPP subunit 33 is referred to in FlyBase by the symbol Dmel\Trs33 (CG6196, FBgn0266722). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:15350345..15350995. It has the cytological map location 88F1. Protein features are: NO signalling/Golgi transport  ligand-binding domain; Transport protein particle (TRAPP) component. Its molecular function is described by: . It is involved in the biological process described with: ER to Golgi vesicle-mediated transport; vesicle-mediated transport. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: flightless; viable."
FBgn0039355	CG4730	0.27665179	0.489014869	0.999936032	NA	KLF8;VEZF1;KLF12;KLF3;ZNF740;MAZ;ZNF281;ZNF362;ZNF32;ZFP1	low;low;low;low;low;low;low;low;low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4730 (FBgn0039355). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:25677072..25678682. It has the cytological map location 96E9. Protein features are: Zinc finger C2H2-type; Zinc finger, AD-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: DNA binding; zinc ion binding. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0058196	Maf1	0.276735901	0.434490233	0.999936032	NA	MAF1	high	NA	NA	NA	NA
FBgn0264255	para	0.276946902	0.493135937	0.999936032	NA	SCN2A;SCN8A;SCN5A;SCN10A;SCN1A;SCN7A;SCN9A;SCN3A;SCN11A;SCN4A;CACNA1A;NALCN;CACNA1C;CACNA1D;CACNA1S	high;high;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;low;low;low;low;low	NA	transmembrane protein	NA	NA
FBgn0033491	CG18011	0.277217578	0.496422583	0.999936032	NA	ZNF133;ZNF343;ZNF423;ZNF451;ZNF521	low;low;low;low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG18011 (FBgn0033491). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:10142338..10146206. It has the cytological map location 46F2-46F3. Protein features are: 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; Zinc finger C2H2-type. Its molecular function is described by: nucleic acid binding. The biological processes in which it is involved are not known. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during pupal stage; partially lethal - majority die; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during early pupal stages, in adult female stages.  "
FBgn0052625	CG32625	0.27727178	0.244887594	0.999936032	NA	GTSF1L;GTSF1	moderate;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32625 (FBgn0052625). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:13756164..13756826. It has the cytological map location 12B10. Protein features are: TRM13/UPF0224 family, U11-48K-like CHHC zinc finger domain. Its molecular function is described by: . It is involved in the biological process described with: . 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0038466	CG8907	0.27742809	0.40675674	0.999936032	NA	EPS8L2;EPS8;EPS8L1;EPS8L3	moderate;moderate;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8907 (FBgn0038466). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:17008269..17012533. It has the cytological map location 89E8. Protein features are: Epidermal growth factor receptor kinase substrate, phosphotyrosine-binding domain; Eps8, SH3 domain; PH domain-like; SH3 domain; Tensin/EPS8 phosphotyrosine-binding domain. Its molecular function is described by: . It is involved in the biological process described with: olfactory behavior. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; some die during pupal stage; lethal - all die before end of pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0040370	CG13375	0.27746739	0.499039075	0.999936032	NA	RASD1;RASD2	moderate;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13375 (FBgn0040370). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:283186..294962. It has the cytological map location 1A1. Protein features are: P-loop containing nucleoside triphosphate hydrolase; Small GTP-binding protein domain; Small GTPase superfamily; Small GTPase superfamily, Ras type. Its molecular function is described by: GTP binding; GTPase activity. It is involved in the biological process described with: signal transduction. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0038930	CG5778	0.277587136	0.4124242	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG5778 (FBgn0038930). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:22085374..22086397. It has the cytological map location 94A2. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed in adults stages of both sexes.
FBgn0052984	CG32984	0.277587136	0.4124242	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32984 (FBgn0052984). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:8964982..8967035. It has the cytological map location 29F6. Protein features are: Alkaline phosphatase-like, alpha/beta/alpha; Alkaline-phosphatase-like, core domain; Protein of unknown function DUF229. Its molecular function is described by: catalytic activity. It is involved in the biological process described with: multicellular organism reproduction; metabolic process. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed in adult female stages.  "
FBgn0264503	CG43902	0.277587136	0.4124242	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG43902 (FBgn0264503). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:10158434..10195337. It has the cytological map location 9B2. Its molecular function is described by: . It is involved in the biological process described with: . 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal - majority die; viable.
FBgn0004861	ph-p	0.277644459	0.508256717	0.999936032	NA	PHC3;PHC2;PHC1	high;moderate;moderate	DNA-binding with transcription factor activity	NA	NA	"The gene polyhomeotic proximal is referred to in FlyBase by the symbol Dmel\ph-p (CG18412, FBgn0004861). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is X:2126210..2138371. It has the cytological map location 2D2-2D3. Protein features are: Armadillo-like helical; Sterile alpha motif domain; Sterile alpha motif/pointed domain; WD40/YVTN repeat-like-containing domain; Zinc finger, FCS-type. Its molecular function is described by: DNA topoisomerase binding; chromatin binding; zinc ion binding; core promoter binding; protein binding; chaperone binding. It is involved in the biological process described with: negative regulation of transcription, DNA-templated; germarium-derived female germ-line cyst encapsulation; response to ecdysone; mitotic sister chromatid segregation; ovarian follicle cell stalk formation; gene silencing; central nervous system neuron development; syncytial blastoderm mitotic cell cycle. 58 alleles are reported. The phenotypes of these alleles manifest in: head segment; biological phase; wing posterior compartment; nucleus; telophase; genitalia; anaphase; embryonic tagma; wing; mushroom body; embryonic/larval digestive system; M phase; compound sense organ; cell. The phenotypic classes of alleles include: phenotype; increased mortality; increased cell number; size defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0031606	CG15439	0.277974841	0.481560601	0.999936032	NA	PHF14	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15439 (FBgn0031606). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:4449295..4453038. It has the cytological map location 24F3. Protein features are: Extended PHD (ePHD) domain; Zinc finger, FYVE/PHD-type; Zinc finger, PHD-finger; Zinc finger, PHD-type; Zinc finger, PHD-type, conserved site; Zinc finger, RING/FYVE/PHD-type. Its molecular function is unknown. It is involved in the biological process described with: lateral inhibition. 6 alleles are reported. The phenotypes of these alleles manifest in: chaeta; mesothoracic tergum. The phenotypic classes of alleles include: visible; viable; lethal - all die during larval stage; fertile; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0259998	CG17571	0.278286357	0.40007687	0.999936032	NA	CTRL;PRSS42;PRSS1;PRSS3	low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17571 (FBgn0259998). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:20255988..20257192. It has the cytological map location 38C3. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of extremely low expression.  Peak expression observed during late larval stages.  "
FBgn0267648	pre-mod(mdg4)-G	0.278372351	0.432783079	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\pre-mod(mdg4)-G (CG45986, FBgn0267648). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:21354445..21359768. It has the cytological map location 93D8. Protein features are: Zinc finger, FLYWCH-type. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported."
FBgn0024194	rasp	0.278376282	0.424707056	0.999936032	NA	HHAT;HHATL	high;moderate	NA	transmembrane protein	NA	"The gene rasp is referred to in FlyBase by the symbol Dmel\rasp (CG11495, FBgn0024194). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:3162180..3163852. It has the cytological map location 63B8. Protein features are: Membrane bound O-acyl transferase, MBOAT. Its molecular function is described by: palmitoyltransferase activity; transferase activity, transferring acyl groups. It is involved in the biological process described with: smoothened signaling pathway; N-terminal peptidyl-L-cysteine N-palmitoylation; dorsal appendage formation; segment polarity determination; protein palmitoylation. 31 alleles are reported. The phenotypes of these alleles manifest in: embryo; embryonic/first instar larval cuticle; chorion; dorsal appendage; egg; wing disc; eye-antennal disc; chorionic specialization; prepupa; embryonic/larval integumentary system. The phenotypic classes of alleles include: phenotype; increased mortality during development; increased mortality; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0051269	CG31269	0.278604573	0.457592396	0.999936032	NA	PROZ;KLK14;KLK7;KLK11;KLK9	low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31269 (FBgn0051269). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:17127126..17128201. It has the cytological map location 89F1. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period, in adult male stages.  "
FBgn0036332	CG11261	0.278660275	0.468104279	0.999936032	NA	CUL1;CACUL1	moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11261 (FBgn0036332). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:13009399..13011685. It has the cytological map location 69F5. Protein features are: Cullin homology; Cullin protein, neddylation domain; Cullin repeat-like-containing domain; Cullin, N-terminal; Winged helix-turn-helix DNA-binding domain. Its molecular function is described by: ubiquitin protein ligase binding; ubiquitin protein ligase activity. It is involved in the biological process described with: protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein catabolic process. 6 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable; fertile; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0030208	PPP4R2r	0.278810423	0.482020709	0.999936032	NA	PPP4R2	high	NA	NA	NA	"The gene Protein phosphatase 4 regulatory subunit 2-related protein is referred to in FlyBase by the symbol Dmel\PPP4R2r (CG2890, FBgn0030208). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is X:10478838..10481943. It has the cytological map location 9D1-9D2. Protein features are: Protein phosphatase 4 core regulatory subunit R2. Its molecular function is described by: protein phosphatase regulator activity. It is involved in the biological process described with: negative regulation of smoothened signaling pathway; mitotic cell cycle. 6 alleles are reported. The phenotypes of these alleles manifest in: neuroblast; ganglion mother cell. The phenotypic classes of alleles include: viable; flightless; lethal; decreased cell number; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, at stages throughout the pupal period.  "
FBgn0011589	Elk	0.278882935	0.448113138	0.999936032	NA	KCNH8;KCNH4;KCNH3	high;moderate;moderate	NA	transmembrane protein	NA	"The gene Eag-like K<sup>+</sup> channel is referred to in FlyBase by the symbol Dmel\Elk (CG5076, FBgn0011589). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:17873939..17926695. It has the cytological map location 54F4-55A2. Protein features are: Cyclic nucleotide-binding domain; Cyclic nucleotide-binding-like; Ion transport domain; PAC motif; PAS domain; PAS-associated, C-terminal; Potassium channel, voltage-dependent, EAG/ELK/ERG; Potassium channel, voltage-dependent, ELK; RmlC-like jelly roll fold. Its molecular function is described by: voltage-gated cation channel activity; phosphorelay sensor kinase activity; voltage-gated potassium channel activity. It is involved in the biological process described with: potassium ion transport; regulation of membrane potential; regulation of glucose metabolic process; phosphorelay signal transduction system; transmembrane transport. 12 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult male stages.  "
FBgn0052786	CG32786	0.278882935	0.448113138	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32786 (FBgn0052786). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:3940847..3944265. It has the cytological map location 3F8-3F9. Its molecular function is described by: . It is involved in the biological process described with: . One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed within 00-06 hour embryonic stages, during early pupal stages, in stages of adults of both sexes.  "
FBgn0085487	CG34458	0.278882935	0.448113138	0.999936032	NA	KLK15;KLK9;CTSG;KLK10;GZMB;KLK12	low;low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG34458 (FBgn0085487). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:16672033..16672889. It has the cytological map location 53D1. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site; TonB box, conserved site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during early larval stages.  "
FBgn0000206	boss	0.279226128	0.270273551	0.999936032	NA	GPRC5B;GPRC5D;GPRC5A;GPRC5C	high;moderate;moderate;moderate	NA	transmembrane protein	GPCR	"The gene bride of sevenless is referred to in FlyBase by the symbol Dmel\boss (CG8285, FBgn0000206). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:25961994..25966948. It has the cytological map location 96F8. Protein features are: Bride of sevenless protein; GPCR family 3, C-terminal. Its molecular function is described by: receptor binding; transmembrane signaling receptor activity; sevenless binding; G-protein coupled receptor activity; transmembrane receptor protein tyrosine kinase activator activity; glutamate receptor activity. It is involved in the biological process described with 12 unique terms, many of which group under: response to stimulus; regulation of biological quality; carbohydrate homeostasis; neuron-neuron synaptic transmission; system process; organonitrogen compound metabolic process; chemical homeostasis; homeostatic process; nitrogen compound metabolic process; response to monosaccharide; cell-cell signaling. 53 alleles are reported. The phenotypes of these alleles manifest in: photoreceptor cell R7; embryonic/larval oenocyte; eye. The phenotypic classes of alleles include: increased mortality during development; phenotype; visible; lethal; lethal - all die before end of P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages.  "
FBgn0024366	CG11409	0.279226128	0.270273551	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG11409 (FBgn0024366). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:1329518..1341587. It has the cytological map location 1F3. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during late pupal stages.
FBgn0025393	CG14795	0.279226128	0.270273551	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14795 (FBgn0025393). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:1512227..1512803. It has the cytological map location 2B1. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; some die during pupal stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0034731	CG10384	0.279226128	0.270273551	0.999936032	NA	KHDRBS2;KHDRBS3;KHDRBS1;QKI	moderate;moderate;moderate;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10384 (FBgn0034731). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:22454741..22472995. It has the cytological map location 58E2-58E3. Protein features are: K Homology domain; K Homology domain, type 1. Its molecular function is described by: RNA binding. The biological processes in which it is involved are not known. 5 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: fertile; viable; visible; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages.  "
FBgn0261998	CG42816	0.279226128	0.270273551	0.999936032	NA	ABCA3;ABCA10;ABCA6;ABCA1;ABCA7;ABCA5;ABCA8;ABCA9	moderate;high;high;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG42816 (FBgn0261998). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:17792088..17797594. It has the cytological map location 75A2. Protein features are: AAA+ ATPase domain; ABC transporter A, ABCA; ABC transporter-like; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: ATP binding; ATPase activity, coupled to transmembrane movement of substances. It is involved in the biological process described with: transport; lipid transport. 9 alleles are reported. No phenotypic data is available. No phenotypic class data is available."
FBgn0037707	RnpS1	0.279257503	0.456370202	0.999936032	NA	RNPS1	high	NA	NA	NA	"The gene RNA-binding protein S1 is referred to in FlyBase by the symbol Dmel\RnpS1 (CG16788, FBgn0037707). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:9552034..9553747. It has the cytological map location 85D24. Protein features are: RNA recognition motif domain; RNPS1, RNA recognition motif. Its molecular function is described by: mRNA binding; nucleic acid binding. It is involved in the biological process described with: RNA splicing; negative regulation of transposition, DNA-mediated. 14 alleles are reported. The phenotype of these alleles manifest in: intersegmental nerve. The phenotypic classes of alleles include: neuroanatomy defective; lethal; female sterile; viable; female semi-sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0037475	Fer1	0.279289146	0.459856366	0.999936032	NA	PTF1A;NHLH2;ASCL5;TCF15;SCX;MESP2;MSGN1;MESP1	high;low;low;low;low;low;moderate;low	DNA-binding with transcription factor activity(HLH)	NA	NA	"The gene 48 related 1 is referred to in FlyBase by the symbol Dmel\Fer1 (CG33323, FBgn0037475). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:7136206..7141972. It has the cytological map location 84C5-84C6. Protein features are: Myc-type, basic helix-loop-helix (bHLH) domain. Its molecular function is described by: protein dimerization activity. It is involved in the biological process described with: regulation of transcription, DNA-templated. 11 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: partially lethal; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 06-24 hour embryonic stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0264353	CR43809	0.279490886	0.505956617	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR43809 (FBgn0264353). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2L:21102586..21104298. It has the cytological map location 39A2. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0267691	CR46027	0.279823447	0.366762179	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR46027 (FBgn0267691). It is a pseudogene_attribute from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2R:12419702..12420291. It has the cytological map location 49A4. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0042175	CG18858	0.279980697	0.40981359	0.999936032	PLA2G15	PLA2G15;LCAT	high;moderate	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG18858 (FBgn0042175). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:20456847..20459075. It has the cytological map location 38C7. Protein features are: Alpha/Beta hydrolase fold; Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase. Its molecular function is described by: O-acyltransferase activity. It is involved in the biological process described with: lipid metabolic process. 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed during early pupal stages.
FBgn0037751	topi	0.280187595	0.486773469	0.999936032	NA	ZBTB24;ZNF785;ZNF331;ZNF543	low;low;low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene matotopetli is referred to in FlyBase by the symbol Dmel\topi (CG8484, FBgn0037751). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:9775121..9777943. It has the cytological map location 85E8. Protein features are: Zinc finger C2H2-type. Its molecular function is described by: nucleic acid binding; protein binding. It is involved in the biological process described with: spermatogenesis; positive regulation of transcription involved in meiotic cell cycle; male meiotic nuclear division. 9 alleles are reported. The phenotypes of these alleles manifest in: nuclear lamina; nucleolus; spermatid; secondary spermatocyte; spermatocyte. The phenotypic classes of alleles include: female fertile; meiotic cell cycle defective; viable; male sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed at stages throughout the pupal period, in adult male stages.  "
FBgn0038897	CG5849	0.280269815	0.465444233	0.999936032	NA	TRHDE;LVRN;ANPEP;ENPEP;LNPEP;ERAP1;ERAP2	moderate;moderate;moderate;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5849 (FBgn0038897). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:21740105..21744431. It has the cytological map location 93F7-93F8. Protein features are: Aminopeptidase N-type; ERAP1-like C-terminal domain; Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase; Peptidase M1, membrane alanine aminopeptidase, N-terminal. Its molecular function is described by: zinc ion binding; metalloaminopeptidase activity; peptide binding. It is involved in the biological process described with: peptide catabolic process; proteolysis. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages.  "
FBgn0026777	Rad23	0.280313566	0.411723033	0.999936032	RAD23B	RAD23B;RAD23A	high;moderate	NA	NA	NA	"The gene Rad23 is referred to in FlyBase by the symbol Dmel\Rad23 (CG1836, FBgn0026777). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 4:308093..310822. It has the cytological map location 102B3. Protein features are: Heat shock chaperonin-binding; UBA-like; UV excision repair protein Rad23; Ubiquitin domain; Ubiquitin-associated domain; Ubiquitin-related domain; XPC-binding domain. Its molecular function is described by: polyubiquitin binding; damaged DNA binding. It is involved in the biological process described with: regulation of proteasomal ubiquitin-dependent protein catabolic process; nucleotide-excision repair, DNA damage recognition. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages.  "
FBgn0030189	CG2909	0.280384947	0.486826428	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG2909 (FBgn0030189). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:10326464..10328946. It has the cytological map location 9B7. Protein features are: Protein of unknown function DUF4804. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal - all die during P-stage; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0262366	CG43064	0.280420513	0.473574353	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG43064 (FBgn0262366). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:11834721..11836721. It has the cytological map location 68E1. Protein features are: Leucine-rich repeat domain, L domain-like. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported."
FBgn0038292	CG3987	0.280433583	0.397944207	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG3987 (FBgn0038292). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:15139958..15141715. It has the cytological map location 88E2. Its molecular function is unknown. It is involved in the biological process described with: mesoderm development. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during late larval stages.
FBgn0030871	CG8142	0.28054074	0.484791971	0.999936032	RFC4	RFC4	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8142 (FBgn0030871). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:17843343..17844704. It has the cytological map location 16E1. Protein features are: AAA+ ATPase domain; ATPase, AAA-type, core; DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal; P-loop containing nucleoside triphosphate hydrolase; Replication factor C, C-terminal. Its molecular function is described by: ATP binding; DNA clamp loader activity. It is involved in the biological process described with: lateral inhibition; DNA-dependent DNA replication; DNA repair. 6 alleles are reported. The phenotypes of these alleles manifest in: chaeta; trichogen cell. The phenotypic classes of alleles include: fertile; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0040007	RpL38	0.28062718	0.397029774	0.999936032	NA	RPL38	high	NA	NA	NA	"The gene Ribosomal protein L38 is referred to in FlyBase by the symbol Dmel\RpL38 (CG18001, FBgn0040007). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:4515388..4516458. It has the cytological map location 41A2. Protein features are: Ribosomal protein L38e. Its molecular function is described by: structural constituent of ribosome; RNA binding. It is involved in the biological process described with: ribonucleoprotein complex assembly; translation; cytoplasmic translation. 11 alleles are reported. The phenotypes of these alleles manifest in: prothoracic gland; wing vein; chaeta. The phenotypic classes of alleles include: increased mortality during development; phenotype; developmental rate defective; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of high expression.  Peak expression observed within 06-24 hour embryonic stages.  "
FBgn0261681	CG42728	0.280662326	0.3043349	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG42728 (FBgn0261681). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:15527620..15528196. It has the cytological map location 71D4-71E1. Protein features are: Chitin binding domain. Its molecular function is described by: chitin binding. It is involved in the biological process described with: chitin metabolic process. No alleles are reported.
FBgn0030509	CG11162	0.280723082	0.413510301	0.999936032	NA	FAXDC2;MSMO1	moderate;moderate	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG11162 (FBgn0030509). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:13676894..13677882. It has the cytological map location 12B2. Protein features are: Fatty acid hydroxylase. Its molecular function is described by: oxidoreductase activity; iron ion binding. It is involved in the biological process described with: lipid metabolic process; oxidation-reduction process; lipid biosynthetic process. One allele is reported. No phenotypic data is available. The phenotypic classes of allele include: viable; short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during late larval stages.
FBgn0027496	epsilonCOP	0.280725504	0.407994826	0.999936032	COPE	COPE	high	NA	NA	NA	"The gene Coat Protein (coatomer) ‘µ is referred to in FlyBase by the symbol Dmel\‘µCOP (CG9543, FBgn0027496). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:6489090..6490194. It has the cytological map location 26D9. Protein features are: Coatomer, epsilon subunit; Tetratricopeptide-like helical domain. Its molecular function is described by: structural molecule activity. It is involved in the biological process described with: ER to Golgi vesicle-mediated transport; intra-Golgi vesicle-mediated transport; retrograde vesicle-mediated transport, Golgi to ER. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0004397	Vinc	0.280842936	0.450051698	0.999936032	NA	VCL	high	NA	NA	NA	"The gene Vinculin is referred to in FlyBase by the symbol Dmel\Vinc (CG3299, FBgn0004397). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is X:2214347..2222567. It has the cytological map location 2E2-2E3. Protein features are: Vinculin; Vinculin, conserved site; Vinculin/alpha-catenin. Its molecular function is described by: structural molecule activity; actin filament binding; actin binding. It is involved in the biological process described with: cell adhesion; phagocytosis; neuron projection morphogenesis; cytoskeletal anchoring at plasma membrane. 32 alleles are reported. The phenotypes of these alleles manifest in: wing cell; muscle attachment site; follicle cell; embryonic somatic muscle; cardiac myofibril; adult heart. The phenotypic classes of alleles include: viable; fertile; lethal; long lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 12-24 hour embryonic stages, during late pupal stages.  "
FBgn0034313	CG5726	0.280847688	0.467513249	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG5726 (FBgn0034313). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:18175255..18180197. It has the cytological map location 55B12. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0032595	CG17996	0.281134082	0.416078068	0.999936032	NA	CMC1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17996 (FBgn0032595). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:16730458..16731039. It has the cytological map location 36A12. Protein features are: Cytochrome c oxidase biogenesis protein Cmc1-like. Its molecular function is described by: copper ion binding. It is involved in the biological process described with: mitochondrial respiratory chain complex IV assembly. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0036772	CG5290	0.281197722	0.49201175	0.999936032	TTC27	TTC27	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5290 (FBgn0036772). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:17909483..17912565. It has the cytological map location 75A8. Protein features are: Tetratricopeptide repeat; Tetratricopeptide repeat-containing domain; Tetratricopeptide-like helical domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 9 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval neuroblast; ganglion mother cell. The phenotypic classes of alleles include: lethal - all die before end of first instar larval stage; lethal - all die during P-stage; phenotype; lethal; some die during P-stage; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.  "
FBgn0036053	iPLA2-VIA	0.281278582	0.451256965	0.999936032	PLA2G6	PLA2G6	high	NA	NA	NA	"The gene calcium-independent phospholipase A2 VIA is referred to in FlyBase by the symbol Dmel\iPLA2-VIA (CG6718, FBgn0036053). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3L:9860217..9864349. It has the cytological map location 67C11. Protein features are: Acyl transferase/acyl hydrolase/lysophospholipase; Ankyrin repeat; Ankyrin repeat-containing domain; Patatin-like phospholipase domain. Its molecular function is unknown. It is involved in the biological process described with: triglyceride homeostasis; positive regulation of response to oxidative stress; lipid metabolic process. 7 alleles are reported. The phenotypes of these alleles manifest in: adult brain; retina; ommatidium; mitochondrion. The phenotypic classes of alleles include: stress response defective; phenotype; viable; female semi-sterile; neuroanatomy defective; chemical sensitive; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0021953	Fatp	0.281301707	0.400032176	0.999936032	NA	SLC27A4;SLC27A1;SLC27A6;SLC27A5;SLC27A2;SLC27A3	moderate;moderate;low;low;low;low	NA	NA	NA	NA
FBgn0033021	CG10417	0.281316611	0.429838979	0.999936032	PPM1G	PPM1G	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10417 (FBgn0033021). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:5360331..5363104. It has the cytological map location 41E5. Protein features are: PPM-type phosphatase domain; PPM-type phosphatase, divalent cation binding; Protein phosphatase 2C family. Its molecular function is described by: protein serine/threonine phosphatase activity; cation binding. It is involved in the biological process described with: protein dephosphorylation. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: female semi-sterile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0000179	bi	0.281533322	0.397695065	0.999936032	NA	TBX2;TBX3;TBX15;TBX1;TBX18;TBX5;TBX4	high;moderate;low;low;low;moderate;moderate	DNA-binding with transcription factor activity(T-box)	NA	NA	"The gene bifid is referred to in FlyBase by the symbol Dmel\bi (CG3578, FBgn0000179). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (5 unique). Gene sequence location is X:4412856..4485647. It has the cytological map location 4C3-4C4. Protein features are: K Homology domain, type 1; Optomotor-blind protein, N-terminal; Transcription factor, T-box; Transcription factor, T-box, conserved site; p53-like transcription factor, DNA-binding. Its molecular function is described by: RNA binding; protein binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding; transcription factor activity, sequence-specific DNA binding; DNA binding. It is involved in the biological process described with: compound eye morphogenesis; wing disc anterior/posterior pattern formation; developmental pigmentation; wing disc morphogenesis; regulation of transcription, DNA-templated; organ growth; imaginal disc-derived wing morphogenesis; negative regulation of transcription from RNA polymerase II promoter. 75 alleles are reported. The phenotypes of these alleles manifest in: wing vein L4; extracellular region part; adult abdominal segment posterior compartment; abdominal segment 3; neuron projection bundle; extracellular region; extracellular matrix; tarsal segment; integumentary specialisation; dorsal margin photoreceptor; wing pouch; male genitalia. The phenotypic classes of alleles include: increased cell number; increased mortality; body color defective; optomotor response defective; visible; increased mortality during development; phenotype; phototaxis defective; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 06-18 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0038641	CG7708	0.281533322	0.397695065	0.999936032	SLC5A7	SLC5A7	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7708 (FBgn0038641). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:18680604..18686739. It has the cytological map location 91C1. Protein features are: Sodium/solute symporter. Its molecular function is described by: choline:sodium symporter activity; choline transmembrane transporter activity; amino acid transmembrane transporter activity; choline binding. It is involved in the biological process described with: choline transport; amino acid transmembrane transport; acetylcholine biosynthetic process. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.  "
FBgn0038516	P5cr-2	0.281637989	0.408925127	0.999936032	NA	PYCR1;PYCRL;PYCR2;LEFTY1	high;moderate;moderate;moderate	NA	NA	NA	"The gene Pyrroline-5-carboxylate reductase-like 2 is referred to in FlyBase by the symbol Dmel\P5cr-2 (CG5840, FBgn0038516). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 3R:17534815..17537136. It has the cytological map location 90B3. Protein features are: 6-phosphogluconate dehydrogenase C-terminal domain-like; NAD(P)-binding domain; Pyrroline-5-carboxylate reductase; Pyrroline-5-carboxylate reductase, catalytic, N-terminal; Pyrroline-5-carboxylate reductase, dimerisation domain. Its molecular function is described by: pyrroline-5-carboxylate reductase activity. It is involved in the biological process described with: oxidation-reduction process; proline biosynthetic process. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 12-18 embryonic stages, during late pupal stages.  "
FBgn0036667	CG9669	0.281680811	0.444858776	0.999936032	TMEM258	TMEM258;MIR611	high;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9669 (FBgn0036667). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:16844568..16844991. It has the cytological map location 73D1. Protein features are: Oligosaccharyltransferase complex subunit. Its molecular function is described by: . It is involved in the biological process described with: protein N-linked glycosylation. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in adult female stages.  "
FBgn0260938	tay	0.281986404	0.460360334	0.999936032	NA	AUTS2;FBRSL1	high;moderate	NA	NA	NA	"The gene tay bridge is referred to in FlyBase by the symbol Dmel\tay (CG9056, FBgn0260938). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is X:15876368..15887311. It has the cytological map location 14A1-14B1. Its molecular function is unknown. It is involved in the biological process described with: negative regulation of epidermal growth factor receptor signaling pathway; adult walking behavior; pattern orientation; imaginal disc-derived wing vein morphogenesis. 21 alleles are reported. The phenotypes of these alleles manifest in: adult thorax; eye; leg; mesothoracic tergum; wing vein; wing; protocerebral bridge. The phenotypic classes of alleles include: locomotor behavior defective; lethal; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during early pupal stages, in adult female stages.  "
FBgn0004431	LysX	0.282100772	0.423226959	0.999936032	NA	LYZ;LALBA;LYZL6;SPACA5B;LYZL1;SPACA5;LYZL2;SPACA3;LYZL4	moderate;low;low;low;low;low;low;low;low	NA	NA	NA	"The gene Lysozyme X is referred to in FlyBase by the symbol Dmel\LysX (CG9120, FBgn0004431). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:1194739..1195302. It has the cytological map location 61F3. Protein features are: Glycoside hydrolase, family 22; Glycoside hydrolase, family 22, conserved site; Glycoside hydrolase, family 22, lysozyme; Lysozyme-like domain. Its molecular function is described by: lysozyme activity. It is involved in the biological process described with: cell wall macromolecule catabolic process; defense response to Gram-positive bacterium; defense response to Gram-negative bacterium. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0002783	mor	0.282147803	0.474707644	0.999936032	NA	SMARCC2;SMARCC1	high;moderate	DNA-binding with transcription factor activity	NA	NA	"The gene moira is referred to in FlyBase by the symbol Dmel\mor (CG18740, FBgn0002783). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:15968134..15972913. It has the cytological map location 89A8-89A11. Protein features are: BRCT domain; Homeobox domain-like; SANT domain; SANT/Myb domain; SMARCC, C-terminal; SMARCC, N-terminal; SMARCC, SWIRM-associated domain; SWI/SNFcomplex subunit SMARCC2; SWIRM domain; Winged helix-turn-helix DNA-binding domain. Its molecular function is described by: protein binding; DNA binding. It is involved in the biological process described with: positive regulation of transcription, DNA-templated; imaginal disc-derived wing margin morphogenesis; regulation of transcription from RNA polymerase II promoter; imaginal disc-derived leg morphogenesis; ATP-dependent chromatin remodeling; regulation of innate immune response; imaginal disc-derived wing vein morphogenesis; imaginal disc-derived wing vein specification; negative regulation of G1/S transition of mitotic cell cycle; negative regulation of neuroblast proliferation. 32 alleles are reported. The phenotypes of these alleles manifest in: cell; mesothoracic tarsal segment; embryonic/larval neuroblast; chorion; chaeta; eo-type sensillum; antennal segment; adult external metathorax; cephalopharyngeal skeleton; terminalia. The phenotypic classes of alleles include: increased mortality during development; phenotype; increased mortality; lethal - all die before end of P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0004647	N	0.282313675	0.496720296	0.999936032	NA	NOTCH1;NOTCH2;NOTCH3;NOTCH4	high;moderate;moderate;moderate	DNA-binding with transcription factor activity	transmembrane protein	NA	"The gene Notch is referred to in FlyBase by the symbol Dmel\N (CG3936, FBgn0004647). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:3134870..3172221. It has the cytological map location 3C7-3C9. Protein features are: Ankyrin repeat; Ankyrin repeat-containing domain; Domain of unknown function DUF3454, notch; EGF-like calcium-binding domain; EGF-like calcium-binding, conserved site; EGF-like domain; EGF-like, conserved site; EGF-type aspartate/asparagine hydroxylation site; Growth factor receptor cysteine-rich domain; Notch; Notch domain; Notch, NOD domain; Notch, NODP domain. Its molecular function is described by: transmembrane signaling receptor activity; calcium ion binding; receptor activity; protein binding; chromatin binding. It is involved in the biological process described with 121 unique terms, many of which group under: respiratory system development; neurological system process; regulation of biological quality; intestinal stem cell homeostasis; cell-cell signaling involved in cell fate commitment; ventral cord development; tripartite regional subdivision; cardiac cell fate specification; aging; cell projection assembly; negative regulation of photoreceptor cell differentiation; nicotinamide nucleotide metabolic process; behavior; regulation of MAPK cascade; cell-cell adhesion via plasma-membrane adhesion molecules; muscle cell fate determination. 629 alleles are reported. The phenotypes of these alleles manifest in: egg; mesothoracic preepisternum; keyhole structure; external sensory organ precursor cell IIa; medial neuron of the ventral midline; glioblast; enteroblast of posterior adult midgut epithelium; wing nerve; single-organism process; stage 4 neuroblast; H-cell; presumptive embryonic/larval peripheral nervous system; abdominal 3 dorsal acute muscle; chorion; presumptive embryonic/larval integumentary system; embryonic/larval salivary gland; embryonic foregut; larval antennal segment; embryonic/larval cuticle; mesothoracic nerve; chordotonal organ precursor cell; cell periphery; prothoracic tibia; embryonic/larval hindgut; dorsal multidendritic neuron ddaD; longitudinal connective; muscle of third axillary 54; larval outer optic anlage; embryonic pericardial cell; stage 8 embryo. The phenotypic classes of alleles include: size defective; increased mortality; fertile; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0053307	CG33307	0.28233132	0.420330742	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG33307 (FBgn0053307). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:13839262..13841520. It has the cytological map location 34D6-34D7. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period.
FBgn0044020	Roc2	0.282443708	0.467484466	0.999936032	NA	RNF7;RBX1	high;moderate	NA	NA	NA	"The gene Regulator of cullins 2 is referred to in FlyBase by the symbol Dmel\Roc2 (CG8998, FBgn0044020). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:11652756..11679354. It has the cytological map location 48B4-48C1. Protein features are: Zinc finger, RING-H2-type; Zinc finger, RING-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: NEDD8 transferase activity; zinc ion binding; ubiquitin protein ligase activity; cullin family protein binding. It is involved in the biological process described with: protein ubiquitination; protein neddylation; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination involved in ubiquitin-dependent protein catabolic process. 35 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0037199	CG11137	0.282448275	0.406383482	0.999936032	NA	EMC4	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11137 (FBgn0037199). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:22867175..22868243. It has the cytological map location 80B1. Protein features are: Protein of unknown function DUF1077, TMEM85. Its molecular function is unknown. It is involved in the biological process described with: protein folding in endoplasmic reticulum. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; lethal - all die during P-stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0266906	CR45366	0.28276154	0.437336572	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45366 (FBgn0266906). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2L:357329..358174. It has the cytological map location 21C1. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available.
FBgn0030613	Rab3-GEF	0.282809576	0.303581363	0.999936032	NA	MADD	high	NA	transmembrane protein	NA	"The gene Rab3 GDP-GTP exchange factor is referred to in FlyBase by the symbol Dmel\Rab3-GEF (CG5627, FBgn0030613). It is a protein_coding_gene from Drosophila melanogaster. It has 10 annotated transcripts and 10 polypeptides (all unique). Gene sequence location is X:15089682..15113762. It has the cytological map location 13A10-13A12. Protein features are: DENN domain; dDENN domain; uDENN domain. Its molecular function is described by: Rab guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: neurotransmitter secretion; regulation of cell cycle; cytoskeletal matrix organization at active zone; vesicle-mediated transport; activation of MAPK activity; regulation of extrinsic apoptotic signaling pathway via death domain receptors; regulation of Rab protein signal transduction. 15 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval neuromuscular junction. The phenotypic classes of alleles include: neuroanatomy defective; viable; neurophysiology defective; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.  "
FBgn0010417	Taf6	0.282894894	0.438352452	0.999936032	NA	TAF6;TAF6L	high;low	DNA-binding with transcription factor activity	NA	NA	"The gene TBP-associated factor 6 is referred to in FlyBase by the symbol Dmel\Taf6 (CG32211, FBgn0010417). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:19599088..19601382. It has the cytological map location 76B9. Protein features are: Armadillo-like helical; Armadillo-type fold; Histone-fold; TAF6, C-terminal HEAT repeat domain; TATA box binding protein associated factor (TAF). Its molecular function is described by: protein heterodimerization activity; transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly. It is involved in the biological process described with: transcription initiation from RNA polymerase II promoter; positive regulation of transcription of Notch receptor target; transcription from RNA polymerase II promoter; regulation of sequence-specific DNA binding transcription factor activity. 16 alleles are reported. The phenotypes of these alleles manifest in: germline cyst; male germline cell; organ system subdivision; chorion; cell; non-membrane-bounded organelle; egg; tagma; ommatidium; intracellular part; dorsal appendage; brain; external encapsulating structure; somatic precursor cell; adult mesothoracic segment; embryonic/larval neuroblast. The phenotypic classes of alleles include: decreased cell number; increased mortality; lethal - all die before end of embryonic stage; visible; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0028292	ric8a	0.282897595	0.454260734	0.999936032	NA	RIC8A;RIC8B;MIR6743	high;moderate;moderate	NA	NA	GPCR	"The gene ric8a is referred to in FlyBase by the symbol Dmel\ric8a (CG15797, FBgn0028292). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:9256168..9259202. It has the cytological map location 8D3. Protein features are: Armadillo-like helical; Armadillo-type fold; Guanine nucleotide exchange factor, Ric8; Synembryn. Its molecular function is described by: GTPase activator activity; guanyl-nucleotide exchange factor activity; G-protein alpha-subunit binding. It is involved in the biological process described with: asymmetric cell division; protein stabilization; neuroblast division; establishment of mitotic spindle localization; establishment or maintenance of cell polarity; gastrulation involving germ band extension; asymmetric protein localization; G-protein coupled receptor signaling pathway. 14 alleles are reported. The phenotypes of these alleles manifest in: EL neuron; embryonic neuroblast; embryonic/first instar larval cuticle; embryo; thecogen cell; spindle; mesothoracic tergum; eo neuron. The phenotypic classes of alleles include: viable; body color defective; lethal - all die before end of larval stage; lethal; some die during larval stage; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0032906	RPA2	0.28311555	0.475508846	0.999936032	RPA2	RPA2;RPA4	high;moderate	NA	NA	NA	"The gene Replication protein A2 is referred to in FlyBase by the symbol Dmel\RPA2 (CG9273, FBgn0032906). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:20924975..20926147. It has the cytological map location 38F6. Protein features are: Nucleic acid-binding, OB-fold; Replication factor A protein 2; Replication protein A, C-terminal; Winged helix-turn-helix DNA-binding domain. Its molecular function is described by: DNA binding. It is involved in the biological process described with: DNA replication; DNA recombination; DNA repair. 9 alleles are reported. The phenotypes of these alleles manifest in: medulla anlage; larval optic anlage; lamina anlage; embryonic/larval neuroblast; ganglion mother cell; mesothoracic tergum; larval outer optic anlage. The phenotypic classes of alleles include: phenotype; some die during P-stage; lethal; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0033484	CG2269	0.283122945	0.347832146	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG2269 (FBgn0033484). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 2R:10085169..10096416. It has the cytological map location 46E3-46E4. Its molecular function is described by: . It is involved in the biological process described with: . 6 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0037618	ouib	0.283122945	0.347832146	0.999936032	NA	ZNF284;ZNF341;ZNF221;ZNF784;ZNF701;ZNF8;ZNF281;ZNF560	low;low;low;low;low;low;low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene ouija board is referred to in FlyBase by the symbol Dmel\ouib (CG11762, FBgn0037618). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:8725479..8726730. It has the cytological map location 85A9. Protein features are: Zinc finger C2H2-type; Zinc finger, AD-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: zinc ion binding; DNA binding; transcription factor activity, sequence-specific DNA binding. It is involved in the biological process described with: instar larval development; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-templated; positive regulation of ecdysteroid biosynthetic process. 9 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed within 00-12 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0265697	CR44504	0.283122945	0.347832146	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44504 (FBgn0265697). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2R:19659645..19661847. It has the cytological map location 56E1. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available.
FBgn0003231	ref(2)P	0.283166552	0.395863995	0.999936032	NA	SQSTM1	high	NA	NA	NA	"The gene refractory to sigma P is referred to in FlyBase by the symbol Dmel\ref(2)P (CG10360, FBgn0003231). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:19542468..19545548. It has the cytological map location 37F1. Protein features are: PB1 domain; Sequestosome-1, UBA domain; UBA-like; Ubiquitin-associated domain; Zinc finger, ZZ-type. Its molecular function is described by: ubiquitin binding; zinc ion binding; identical protein binding. It is involved in the biological process described with: mitochondrion organization; sperm mitochondrion organization; ubiquitin-dependent protein catabolic process. 54 alleles are reported. The phenotypes of these alleles manifest in: indirect flight muscle; mitochondrial derivative; Nebenkern; mitochondrion. The phenotypic classes of alleles include: stress response defective; short lived; male sterile; locomotor behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, during late larval stages, during early pupal stages, in stages of adults of both sexes.  "
FBgn0038286	CG6966	0.283210019	0.471692439	0.999936032	NA	FEM1C;FEM1A;FEM1B	high;moderate;low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG6966 (FBgn0038286). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:15079320..15095631. It has the cytological map location 88E1. Protein features are: Ankyrin repeat; Ankyrin repeat-containing domain; Winged helix-turn-helix DNA-binding domain. Its molecular function is described by: ubiquitin-protein transferase activity. It is involved in the biological process described with: regulation of ubiquitin-protein transferase activity. 10 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed during late pupal stages.
FBgn0034047	CG12970	0.28322341	0.46054833	0.999936032	NA	MB21D1	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG12970 (FBgn0034047). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:15855961..15857522. It has the cytological map location 52C8. Protein features are: Mab-21 domain. Its molecular function is described by: . It is involved in the biological process described with: . One allele is reported. The phenotype of this allele manifest in: trichogen cell. The phenotypic classes of allele include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very low expression to a trough of no expression detected.  Peak expression observed in adults stages of both sexes.
FBgn0035879	GAPcenA	0.283311529	0.467193181	0.999936032	NA	RABGAP1;RABGAP1L	high;moderate	NA	NA	NA	"The gene GTPase activating protein and centrosome-associated is referred to in FlyBase by the symbol Dmel\GAPcenA (CG7112, FBgn0035879). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:8346561..8352279. It has the cytological map location 66C8. Protein features are: Kinesin-like; PH domain-like; PTB/PI domain; Rab GTPase-activating protein 1; Rab-GTPase-TBC domain. Its molecular function is described by: GTPase activator activity; Rab GTPase binding. It is involved in the biological process described with: intracellular protein transport; positive regulation of GTPase activity; regulation of vesicle fusion; regulation of GTPase activity; cell cycle; activation of GTPase activity. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0053207	pxb	0.283415255	0.475068997	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene pxb is referred to in FlyBase by the symbol Dmel\pxb (CG33207, FBgn0053207). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:15666183..15690513. It has the cytological map location 89A1-89A2. Its molecular function is unknown. It is involved in the biological process described with: smoothened signaling pathway; olfactory learning; negative regulation of hemocyte proliferation; long-term memory; mushroom body development; inter-male aggressive behavior; behavioral response to ethanol; learning or memory. 13 alleles are reported. The phenotypes of these alleles manifest in: posterior scutellar bristle; anterior scutellar bristle; macrochaeta. The phenotypic classes of alleles include: fertile; memory defective; viable; chemical sensitive; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-18 hour embryonic stages.  "
FBgn0267793	CR45232	0.283415255	0.475068997	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45232 (FBgn0267793). It is a non_protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts. Gene sequence location is 2R:16297449..16306695. It has the cytological map location 53B2. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported.
FBgn0032836	CG10680	0.283819105	0.498482423	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10680 (FBgn0032836). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:19964136..19965702. It has the cytological map location 38A8. Its molecular function is described by: . It is involved in the biological process described with: . 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: flightless; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed during late pupal stages, in stages of adults of both sexes.  "
FBgn0002939	ninaD	0.283969828	0.393554504	0.999936032	NA	SCARB1;SCARB2;CD36	moderate;low;low	NA	transmembrane protein	NA	"The gene neither inactivation nor afterpotential D is referred to in FlyBase by the symbol Dmel\ninaD (CG31783, FBgn0002939). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:18081628..18083608. It has the cytological map location 36E3. Protein features are: CD36 family. Its molecular function is described by: scavenger receptor activity. It is involved in the biological process described with: rhodopsin biosynthetic process; carotenoid transport; phototransduction, UV; phototransduction; phototransduction, visible light. 12 alleles are reported. The phenotype of these alleles manifest in: photoreceptor cell. The phenotypic classes of alleles include: lethal; viable; neurophysiology defective; lethal - all die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during late larval stages, in adult male stages.  "
FBgn0030486	Set2	0.284069781	0.492441726	0.999936032	NA	SETD2;SETD1A	high;low	DNA-binding with transcription factor activity(AT_hook)	NA	NA	"The gene SET domain containing 2 is referred to in FlyBase by the symbol Dmel\Set2 (CG1716, FBgn0030486). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:13413242..13421024. It has the cytological map location 11F4-11F5. Protein features are: AT hook, DNA-binding motif; AWS domain; Post-SET domain; SET domain; SRI, Set2 Rpb1 interacting; WW domain. Its molecular function is described by: DNA binding; histone-lysine N-methyltransferase activity; phosphoprotein binding; histone methyltransferase activity (H3-K36 specific). It is involved in the biological process described with: regulation of transcription, DNA-templated; wing disc development; instar larval development; ecdysone receptor-mediated signaling pathway; histone H3-K36 methylation; histone methylation. 9 alleles are reported. The phenotypes of these alleles manifest in: eye; wing. The phenotypic classes of alleles include: some die during third instar larval stage; viable; visible; developmental rate defective; lethal - all die before end of larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0017561	Ork1	0.284194867	0.473478489	0.999936032	NA	KCNK4;KCNK17;KCNK5;KCNK16;KCNK10;KCNK2;KCNK3;KCNK18	high;high;high;high;moderate;moderate;low;low	NA	transmembrane protein	NA	"The gene Open rectifier K<sup>+</sup> channel 1 is referred to in FlyBase by the symbol Dmel\Ork1 (CG1615, FBgn0017561). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is X:10878054..10891250. It has the cytological map location 9F7-9F8. Protein features are: Potassium channel domain; Two pore domain potassium channel. Its molecular function is described by: potassium ion leak channel activity; protein homodimerization activity. It is involved in the biological process described with: stabilization of membrane potential; locomotor rhythm; potassium ion transmembrane transport; regulation of heart rate. 16 alleles are reported. The phenotypes of these alleles manifest in: Kenyon cell; projection neuron; presynaptic active zone; abdominal anterior ventral multidendritic neuron vdaa; embryonic/larval olfactory receptor neuron; embryonic/larval heart. The phenotypic classes of alleles include: neurophysiology defective; phenotype; developmental rate defective; increased mortality; behavior defective; neuroanatomy defective; small body. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0052016	4E-T	0.284971901	0.454030755	0.999936032	NA	EIF4ENIF1	high	NA	NA	NA	"The gene eIF4E-Transporter is referred to in FlyBase by the symbol Dmel\4E-T (CG32016, FBgn0052016). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 4:951542..958392. It has the cytological map location 102F3. Protein features are: Eukaryotic translation initiation factor 4E binding protein. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: pain response defective; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0030615	Cyp4s3	0.285275809	0.302516459	0.999936032	NA	CYP4A11;CYP4A22;CYP4Z1;CYP4B1;CYP4X1;CYP4V2;CYP4F11;CYP4F12;CYP19A1;CYP4F8;CYP4F3;CYP4F2;CYP4F22	high;high;moderate;moderate;moderate;low;moderate;low;moderate;moderate;low;low;moderate	NA	NA	NA	"The gene Cyp4s3 is referred to in FlyBase by the symbol Dmel\Cyp4s3 (CG9081, FBgn0030615). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:15113302..15116542. It has the cytological map location 13A12. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Its molecular function is described by: heme binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; iron ion binding. It is involved in the biological process described with: oxidation-reduction process. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0040271	Sulf1	0.285286833	0.473069093	0.999936032	NA	SULF1;SULF2	high;high	NA	transmembrane protein	NA	"The gene Sulfated is referred to in FlyBase by the symbol Dmel\Sulf1 (CG6725, FBgn0040271). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:16310542..16339575. It has the cytological map location 89B12-89B13. Protein features are: Alkaline phosphatase-like, alpha/beta/alpha; Alkaline-phosphatase-like, core domain; Extracellular sulfatase, C-terminal; Sulfatase, N-terminal; Sulfatase, conserved site. Its molecular function is described by: N-acetylglucosamine-6-sulfatase activity. It is involved in the biological process described with: heparin metabolic process; negative regulation of epidermal growth factor receptor signaling pathway; negative regulation of smoothened signaling pathway; negative regulation of Wnt signaling pathway; positive regulation of smoothened signaling pathway; synaptic target inhibition; motor neuron axon guidance. 23 alleles are reported. The phenotypes of these alleles manifest in: eo-type sensillum; compound sense organ; eo support cell; chaeta; chemosensory sensory organ; embryo; wing vein L4; wing vein L5; adult head; developing embryonic structure. The phenotypic classes of alleles include: increased occurrence of cell division; increased mortality; phenotype; increased mortality during development; visible; decreased occurrence of cell division. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the pupal period.  "
FBgn0032034	Rcd4	0.285297414	0.473608747	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Reduction in Cnn dots 4 is referred to in FlyBase by the symbol Dmel\Rcd4 (CG17295, FBgn0032034). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:8382861..8383657. It has the cytological map location 29B4. Protein features are: Protein phosphatase 1 regulatory subunit 35, C-terminal. Its molecular function is unknown. It is involved in the biological process described with: centriole replication. 7 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: increased mortality; visible; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0264834	CR44042	0.285433104	0.382141227	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44042 (FBgn0264834). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2R:1348167..1349167. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0028377	gdl-ORF39	0.285689052	0.236611038	0.999936032	NA	NA	NA	NA	NA	NA	"The gene gdl-ORF39 is referred to in FlyBase by the symbol Dmel\gdl-ORF39 (CG33755, FBgn0028377). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:15509445..15510837. It has the cytological map location 71D3. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during late pupal stages, in adult male stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0003483	spn-E	0.285764108	0.327979129	0.999936032	NA	TDRD9	high	NA	NA	NA	"The gene spindle E is referred to in FlyBase by the symbol Dmel\spn-E (CG3158, FBgn0003483). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:15837419..15844415. It has the cytological map location 89A5. Protein features are: DEAD/DEAH box helicase domain; Helicase superfamily 1/2, ATP-binding domain; Helicase, C-terminal; Helicase-associated domain; P-loop containing nucleoside triphosphate hydrolase; Staphylococcal nuclease (SNase-like), OB-fold/extended TUDOR domain; Tudor domain; Zinc finger C2H2-type. Its molecular function is described by: RNA-dependent ATPase activity; helicase activity; RNA binding; RNA helicase activity; ATP-dependent RNA helicase activity; ATP binding. It is involved in the biological process described with 22 unique terms, many of which group under: chromosome condensation; regulation of embryonic pattern specification; positive regulation of mRNA catabolic process; single-organism metabolic process; cellular component morphogenesis; cell cycle process; polarity specification of dorsal/ventral axis; macromolecule catabolic process; ribonucleoprotein complex biogenesis; DNA conformation change; oocyte fate determination. 40 alleles are reported. The phenotypes of these alleles manifest in: karyosome; egg; microtubule; germline cyst; synaptonemal complex; egg chamber; dorsal appendage; spermatocyte; oocyte. The phenotypic classes of alleles include: female sterile; lethal; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0085384	CG34355	0.285764108	0.327979129	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG34355 (FBgn0085384). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 3R:23803859..23859167. It has the cytological map location 95B8-95C5. Protein features are: DM13 domain; DOMON domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 15 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages.
FBgn0038593	Vps39	0.286072237	0.46384505	0.999936032	NA	VPS39;TGFBRAP1	high;moderate	NA	NA	NA	"The gene Vacuolar protein sorting 39 is referred to in FlyBase by the symbol Dmel\Vps39 (CG7146, FBgn0038593). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:18271189..18274446. It has the cytological map location 91A1. Protein features are: Citron homology (CNH) domain; Clathrin, heavy chain/VPS, 7-fold repeat; Tetratricopeptide-like helical domain; VAM6/VPS39 family; Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1; Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: Rab GTPase binding. It is involved in the biological process described with: cellular response to starvation; neuron projection morphogenesis; vesicle-mediated transport; intracellular protein transport; regulation of Notch signaling pathway; autophagosome maturation; regulation of SNARE complex assembly. 4 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval fat body; late endosome; trichogen cell; autolysosome; embryonic/larval garland cell; vacuole; mesothoracic tergum. The phenotypic classes of alleles include: viable; visible; body color defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0038476	kuk	0.286091916	0.495773571	0.999936032	NA	NA	NA	NA	NA	NA	"The gene kugelkern is referred to in FlyBase by the symbol Dmel\kuk (CG5175, FBgn0038476). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:17080244..17084781. It has the cytological map location 89E12. Its molecular function is unknown. It is involved in the biological process described with: nucleus organization; cellularization; adult locomotory behavior; cell aging; morphogenesis of embryonic epithelium. 14 alleles are reported. The phenotypes of these alleles manifest in: longitudinal muscle; brain; nucleus; nuclear envelope; embryo. The phenotypic classes of alleles include: viable; fertile; short lived; gravitaxis defective; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0003975	vg	0.286417087	0.286999751	0.999936032	NA	VGLL2;VGLL3;VGLL1	high;moderate;moderate	Co-factor	NA	NA	"The gene vestigial is referred to in FlyBase by the symbol Dmel\vg (CG3830, FBgn0003975). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:12884632..12899385. It has the cytological map location 49E1. Protein features are: TDU repeat; Vestigial familiy. Its molecular function is described by: transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; protein C-terminus binding; protein binding. It is involved in the biological process described with 17 unique terms, many of which group under: cell communication; positive regulation of macromolecule biosynthetic process; somatic muscle development; leg disc development; cell cycle; compound eye morphogenesis; determination of muscle attachment site; aromatic compound biosynthetic process; eye morphogenesis; mitotic cell cycle; growth; positive regulation of nucleic acid-templated transcription; proximal/distal pattern formation. 431 alleles are reported. The phenotypes of these alleles manifest in: female organism; metathoracic leg; A2-7 ventral oblique muscle 6; trichome; embryonic/larval cardial cell; ovariole; tibia; integumentary specialisation; eye-antennal disc; ventral longitudinal muscle. The phenotypic classes of alleles include: phenotype; increased mortality during development; fertile; cell cycle defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed at stages throughout the pupal period.  "
FBgn0014133	bif	0.286525889	0.403950367	0.999936032	NA	TMEM57	low	NA	NA	NA	"The gene bifocal is referred to in FlyBase by the symbol Dmel\bif (CG1822, FBgn0014133). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (all unique). Gene sequence location is X:11678970..11694740. It has the cytological map location 10D4-10D5. Protein features are: WD40/YVTN repeat-like-containing domain. Its molecular function is described by: actin binding; microtubule binding; actin filament binding. It is involved in the biological process described with: female meiosis chromosome segregation; axon guidance; negative regulation of axon extension. 37 alleles are reported. The phenotypes of these alleles manifest in: sensory system; cell; supramolecular complex; sensory system neuron; cytoskeleton; rhabdomere; anlage; supramolecular polymer; sensory neuron; macrochaeta; plasma membrane bounded cell projection. The phenotypic classes of alleles include: meiotic cell cycle defective; visible; viable; fertile; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0013679	mt:ND1	0.286742113	0.389125439	0.999936032	NA	ND1	high	NA	transmembrane protein	NA	"The gene mitochondrial NADH-ubiquinone oxidoreductase chain 1 is referred to in FlyBase by the symbol Dmel\mt:ND1 (CG34092, FBgn0013679). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is mitochondrion_genome:11721..12659. Protein features are: NADH:ubiquinone oxidoreductase, subunit 1, conserved site; NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H. Its molecular function is unknown. It is involved in the biological process described with: cellular respiration. 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed within 00-06 and 18-24 hour embryonic stages.  "
FBgn0033075	Pld	0.286949404	0.42149981	0.999936032	NA	PLD2;PLD1	high;moderate	NA	NA	NA	"The gene Phospholipase D is referred to in FlyBase by the symbol Dmel\Pld (CG12110, FBgn0033075). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (3 unique). Gene sequence location is 2R:6242004..6255266. It has the cytological map location 42A14. Protein features are: PH domain-like; Phospholipase D family; Phospholipase D-like domain; Phospholipase D/Transphosphatidylase; Phox homologous domain. Its molecular function is described by: phosphatidylinositol binding; phospholipase D activity. It is involved in the biological process described with: gastrulation involving germ band extension; positive regulation of Golgi vesicle fusion to target membrane; Golgi organization; phototransduction; cellularization. 20 alleles are reported. The phenotypes of these alleles manifest in: ommatidium; retina; rhabdomere; eye photoreceptor cell; Golgi-associated vesicle. The phenotypic classes of alleles include: some die during embryonic stage; partially lethal - majority die; viable; neurophysiology defective; lethal - all die before end of embryonic stage; developmental rate defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.  "
FBgn0035211	CG2211	0.286979975	0.462130851	0.999936032	NA	JMJD6	low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG2211 (FBgn0035211). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:1333239..1335359. It has the cytological map location 61F6-61F7. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0020378	Sp1	0.287321812	0.30735881	0.999936032	NA	SP9;SP8;SP7;SP6;SP2;SP5	high;moderate;moderate;moderate;low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene Sp1 is referred to in FlyBase by the symbol Dmel\Sp1 (CG1343, FBgn0020378). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is X:9729648..9756369. It has the cytological map location 9A1. Protein features are: Zinc finger C2H2-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: transcription factor activity, sequence-specific DNA binding; sequence-specific DNA binding; RNA polymerase II transcription factor activity, sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated; regulation of transcription from RNA polymerase II promoter; imaginal disc-derived leg morphogenesis. 13 alleles are reported. The phenotypes of these alleles manifest in: first segment of antenna; portion of tissue; larval thorax; sense organ; prepupa; pupa; adult mesothoracic sensillum; larva; larval segment; larval thoracic segment. The phenotypic classes of alleles include: visible; viable; homeotic; lethal; cell shape defective; size defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 06-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0035608	blanks	0.287321812	0.30735881	0.999936032	NA	STAU1;STAU2;ADARB1;ADARB2	low;low;low;low	NA	NA	NA	"The gene blanks is referred to in FlyBase by the symbol Dmel\blanks (CG10630, FBgn0035608). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:5497523..5498958. It has the cytological map location 64D2. Its molecular function is described by: siRNA binding. It is involved in the biological process described with: regulation of chromatin silencing; RNA interference; sperm individualization; heterochromatin organization involved in chromatin silencing. 10 alleles are reported. The phenotypes of these alleles manifest in: elongation stage spermatid; individualization stage spermatid; sperm individualization complex; spermatozoon. The phenotypic classes of alleles include: suppressor of variegation; female fertile; lethal; male sterile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the pupal period, in adult male stages.  "
FBgn0051345	CG31345	0.287321812	0.30735881	0.999936032	NA	CAPSL;CAPS;CAPS2	high;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31345 (FBgn0051345). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:12811145..12817029. It has the cytological map location 87D1. Protein features are: EF-Hand 1, calcium-binding site; EF-hand domain; EF-hand domain pair. Its molecular function is described by: calcium ion binding. It is involved in the biological process described with: phagocytosis. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.  "
FBgn0036488	CG6878	0.28767931	0.41359025	0.999936032	ROMO1	ROMO1	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6878 (FBgn0036488). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:15161817..15162470. It has the cytological map location 71B6. Protein features are: Romo1/Mgr2. Its molecular function is unknown. It is involved in the biological process described with: regulation of mitophagy. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 06-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0037780	ohgt	0.287807672	0.459624855	0.999936032	NA	CRBN	high	NA	NA	NA	"The gene ohgata is referred to in FlyBase by the symbol Dmel\ohgt (CG3925, FBgn0037780). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:10049199..10051527. It has the cytological map location 85F8. Protein features are: CULT domain; Lon, substrate-binding domain; Yippee/Mis18/Cereblon. Its molecular function is described by: . It is involved in the biological process described with: protein ubiquitination; negative regulation of insulin-like growth factor receptor signaling pathway. 6 alleles are reported. The phenotype of these alleles manifest in: wing blade. The phenotypic classes of alleles include: phenotype; visible; fertile; size defective; cell number defective; body size defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0027514	CG1024	0.287815285	0.491079242	0.999936032	NA	CTCF;CTCFL	low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG1024 (FBgn0027514). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:6377349..6380328. It has the cytological map location 83E5. Protein features are: Zinc finger C2H2-type. Its molecular function is described by: nucleic acid binding. The biological processes in which it is involved are not known. 5 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; wing; mesothoracic tergum; ganglion mother cell; embryonic/larval neuroblast. The phenotypic classes of alleles include: some die during pupal stage; lethal - all die before end of pupal stage; neuroanatomy defective; visible; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0034913	Snap29	0.287833293	0.422148529	0.999936032	NA	SNAP29	high	NA	NA	NA	"The gene Synaptosomal-associated protein 29kDa is referred to in FlyBase by the symbol Dmel\Snap29 (CG11173, FBgn0034913). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:23843483..23844763. It has the cytological map location 60A3. Protein features are: Target SNARE coiled-coil homology domain. Its molecular function is described by: SNARE binding; SNAP receptor activity; syntaxin binding. It is involved in the biological process described with: autophagosome maturation; negative regulation of secretion by cell; synaptic vesicle priming; synaptic vesicle fusion to presynaptic active zone membrane; regulation of endocytosis; Golgi organization; vesicle-mediated transport. 12 alleles are reported. The phenotypes of these alleles manifest in: eye-antennal disc; dopaminergic PPL1 neuron; autophagosome; Golgi cisterna; embryonic/larval fat body; wing. The phenotypic classes of alleles include: viable; visible; short lived; lethal; partially lethal - majority die; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 06-12 hour embryonic stages, during early pupal stages.  "
FBgn0024293	Spn43Ab	0.287961662	0.475786493	0.999936032	NA	SERPINI2;SERPINI1;SERPINB7;SERPINE2;SERPINE1;SERPIND1;SERPINE3;SERPINB9;SERPINB10;SERPINB12;SERPINB2;SERPINB11;SERPINB4;SERPINA9;SERPINA5;SERPINB13;SERPINB5;SERPINB6;SERPINB1;SERPINB8;SERPINA6	moderate;moderate;moderate;low;low;low;low;low;low;low;low;low;low;low;moderate;low;moderate;low;low;moderate;moderate	NA	NA	NA	"The gene Serpin 43Ab is referred to in FlyBase by the symbol Dmel\Spn43Ab (CG1865, FBgn0024293). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:7151662..7153642. It has the cytological map location 42F3. Protein features are: Serpin domain; Serpin family; Serpin, conserved site. Its molecular function is unknown. It is involved in the biological process described with: multicellular organism reproduction. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.  "
FBgn0023495	Lip3	0.28805941	0.301809891	0.999936032	NA	LIPA;LIPK;LIPF;LIPM;LIPJ;LIPN	high;moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"The gene Lip3 is referred to in FlyBase by the symbol Dmel\Lip3 (CG8823, FBgn0023495). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:13370240..13371904. It has the cytological map location 87E8. Protein features are: Alpha/Beta hydrolase fold; Lipase, eukaryotic; Partial AB-hydrolase lipase domain. Its molecular function is described by: hydrolase activity, acting on ester bonds. It is involved in the biological process described with: lipid metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during early larval stages.  "
FBgn0035533	Cip4	0.288106042	0.443888542	0.999936032	NA	TRIP10;FNBP1;FNBP1L	high;moderate;moderate	NA	NA	NA	"The gene Cdc42-interacting protein 4 is referred to in FlyBase by the symbol Dmel\Cip4 (CG15015, FBgn0035533). It is a protein_coding_gene from Drosophila melanogaster. It has 11 annotated transcripts and 11 polypeptides (10 unique). Gene sequence location is 3L:4322491..4364102. It has the cytological map location 64B1-64B2. Protein features are: Arfaptin homology (AH) domain/BAR domain; F-BAR domain; FCH domain; Formin-binding protein 1; HR1 rho-binding repeat; SH3 domain. Its molecular function is described by: lipid binding; protein binding; GTPase activating protein binding; phospholipid binding. It is involved in the biological process described with 15 unique terms, many of which group under: macromolecule localization; localization; membrane organization; protein localization; multi-organism process; cellular response to stimulus; establishment of localization; post-embryonic development; endocytosis; endomembrane system organization; mesoderm development; epithelial tube morphogenesis. 35 alleles are reported. The phenotypes of these alleles manifest in: egg chamber; wing; neuromuscular junction; bouton; adherens junction; wing hair; NMJ bouton. The phenotypic classes of alleles include: neuroanatomy defective; partially lethal - majority die; increased mortality; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during early pupal stages.  "
FBgn0033935	Sin1	0.288273922	0.479064396	0.999936032	MAPKAP1	MAPKAP1	high	NA	NA	NA	"The gene SAPK-interacting protein 1 is referred to in FlyBase by the symbol Dmel\Sin1 (CG10105, FBgn0033935). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:14411825..14413851. It has the cytological map location 51A2. Protein features are: SAPK-interacting protein 1, Pleckstrin-homology domain; Sin1, N-terminal; Sin1, middle CRIM domain; TORC2 component Sin1/Avo1. Its molecular function is described by: protein kinase binding; phosphatidylinositol-4,5-bisphosphate binding. It is involved in the biological process described with: regulation of protein phosphorylation; TORC2 signaling; stress-activated protein kinase signaling cascade; stress granule assembly; synaptic growth at neuromuscular junction; dendrite morphogenesis; establishment or maintenance of actin cytoskeleton polarity. 7 alleles are reported. The phenotypes of these alleles manifest in: dendrite; class IV dendritic arborizing neuron; embryonic/larval neuromuscular junction; ventral multidendritic neuron vdaB; abdominal anterior ventral multidendritic neuron vdaa; cytoplasmic stress granule; dorsal multidendritic neuron ddaC; embryonic/larval hemocyte. The phenotypic classes of alleles include: neuroanatomy defective; heat stress response defective; fertile; short lived; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, during late pupal stages.  "
FBgn0001977	CIAPIN1	0.288453545	0.414010834	0.999936032	NA	CIAPIN1	high	NA	NA	NA	"The gene Cytokine induced apoptosis inhibitor 1 is referred to in FlyBase by the symbol Dmel\CIAPIN1 (CG4180, FBgn0001977). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:15036293..15038861. It has the cytological map location 35B8. Protein features are: Anamorsin. Its molecular function is described by: iron-sulfur cluster binding. It is involved in the biological process described with: ovarian follicle cell development; sleep; negative regulation of apoptotic process; iron-sulfur cluster assembly. 16 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: increased mortality during development; phenotype; lethal - all die before end of larval stage; increased mortality; lethal - all die before end of second instar larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed during late larval stages, at stages throughout the pupal period.  "
FBgn0051636	CG31636	0.288626746	0.396487449	0.999936032	NA	TTPAL;CLVS1;RLBP1;CLVS2;TTPA	moderate;moderate;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31636 (FBgn0051636). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:6656459..6658152. It has the cytological map location 26F5. Protein features are: CRAL-TRIO lipid binding domain; CRAL/TRIO, N-terminal domain; Cellular retinaldehyde binding/alpha-tocopherol transport. Its molecular function is described by: transporter activity. It is involved in the biological process described with: transport. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed during early pupal stages.  "
FBgn0030354	Upf1	0.288637358	0.441991325	0.999936032	UPF1	UPF1	high	NA	NA	NA	"The gene Upf1 is referred to in FlyBase by the symbol Dmel\Upf1 (CG1559, FBgn0030354). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:11899996..11905371. It has the cytological map location 10F4. Protein features are: Helicase/UvrB, N-terminal; P-loop containing nucleoside triphosphate hydrolase; RNA helicase UPF1, UPF2-interacting domain. Its molecular function is described by: ATP binding; helicase activity; zinc ion binding; DNA binding. It is involved in the biological process described with: positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; cellular response to hypoxia. 16 alleles are reported. The phenotypes of these alleles manifest in: dorsal appendage; eye; adult tracheal system; follicle cell; embryo. The phenotypic classes of alleles include: lethal - all die before end of second instar larval stage; lethal - all die before end of larval stage; lethal; some die during second instar larval stage; some die during third instar larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages, during early pupal stages, in adult female stages.  "
FBgn0028693	Rpn12	0.288876544	0.395053935	0.999936032	PSMD8	PSMD8	high	NA	NA	NA	"The gene Regulatory particle non-ATPase 12 is referred to in FlyBase by the symbol Dmel\Rpn12 (CG4157, FBgn0028693). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:16583028..16584022. It has the cytological map location 73A10. Protein features are: 26S proteasome non-ATPase regulatory subunit Rpn12; CSN8/PSMD8/EIF3K; Winged helix-turn-helix DNA-binding domain. Its molecular function is described by: . It is involved in the biological process described with: proteasome-mediated ubiquitin-dependent protein catabolic process; proteasome assembly; ubiquitin-dependent protein catabolic process. 6 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval neuroblast; ganglion mother cell. The phenotypic classes of alleles include: partially lethal; neuroanatomy defective; lethal - all die during P-stage; viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.  "
FBgn0086442	mib2	0.288928983	0.438618818	0.999936032	NA	MIB2;MIB1	high;low	NA	NA	NA	"The gene mind bomb 2 is referred to in FlyBase by the symbol Dmel\mib2 (CG17492, FBgn0086442). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:19034444..19041541. It has the cytological map location 37B10. Protein features are: Ankyrin repeat; Ankyrin repeat-containing domain; Mib-herc2; Zinc finger, RING-type; Zinc finger, RING/FYVE/PHD-type; Zinc finger, ZZ-type. Its molecular function is described by: myosin II light chain binding; myosin II heavy chain binding; zinc ion binding; ubiquitin-protein transferase activity. It is involved in the biological process described with: protein polyubiquitination; muscle cell cellular homeostasis; myoblast fusion. 34 alleles are reported. The phenotypes of these alleles manifest in: integumentary system; extended germ band embryo; gut section; embryonic/larval midgut primordium; larval abdominal segment A1-7; presumptive embryonic/larval digestive system; somatic mesoderm derivative; cuticle; circulatory system; alimentary canal; stage 16 embryo. The phenotypic classes of alleles include: visible; phenotype; increased mortality during development; cell death defective; lethal - all die before end of P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0040298	Myt1	0.288933342	0.484437285	0.999936032	NA	PKMYT1;WEE1	high;low	NA	NA	NA	"The gene Myt1 is referred to in FlyBase by the symbol Dmel\Myt1 (CG32417, FBgn0040298). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:5777476..5779591. It has the cytological map location 64E7. Protein features are: Protein kinase domain; Protein kinase, ATP binding site; Protein kinase-like domain; Serine/threonine-protein kinase, active site; Tyrosine/threonine-protein kinase, Cdc2 inhibitor. Its molecular function is described by: protein kinase activity; ATP binding; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity. It is involved in the biological process described with 11 unique terms, many of which group under: spermatocyte division; macromolecule metabolic process; organic substance metabolic process; negative regulation of cell cycle phase transition; cell development; cellular metabolic process; oogenesis; regulation of biological quality; female meiotic nuclear division; DNA integrity checkpoint; phosphorus metabolic process; positive regulation of cell size; asymmetric cell division. 17 alleles are reported. The phenotypes of these alleles manifest in: cell; retinal pigment cell; pigment cell; membrane-bounded organelle; germline stem cell; rhabdomere; male reproductive system; microtubule organizing center; embryonic/larval imaginal precursor; imaginal precursor; eye-antennal disc; male organism; organelle lumen. The phenotypic classes of alleles include: cell cycle defective; increased mortality during development; phenotype; sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0015521	RpS21	0.288938656	0.396898541	0.999936032	NA	RPS21	high	NA	NA	NA	"The gene Ribosomal protein S21 is referred to in FlyBase by the symbol Dmel\RpS21 (CG2986, FBgn0015521). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (2 unique). Gene sequence location is 2L:2856070..2857029. It has the cytological map location 23B5-23B6. Protein features are: Ribosomal protein S21e; Ribosomal protein S21e, conserved site. Its molecular function is described by: ribosome binding; structural constituent of ribosome. It is involved in the biological process described with: regulation of cell proliferation; translation; lymph gland development; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); cytoplasmic translation. 12 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval lymph gland; primary lobe of embryonic/larval lymph gland; wing disc; ventral thoracic disc; adult head; embryonic/larval brain; imaginal disc; macrochaeta; embryonic/larval hemocyte; scutum. The phenotypic classes of alleles include: lethal; increased mortality; developmental rate defective; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed within 06-24 hour embryonic stages, during early larval stages.  "
FBgn0083969	CG34133	0.289058754	0.472490517	0.999936032	NA	WDR44	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG34133 (FBgn0083969). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3R:29869365..29875159. It has the cytological map location 99C5. Protein features are: G-protein beta WD-40 repeat; WD40 repeat; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable; lethal - all die before end of pupal stage; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0033320	CG8586	0.289090898	0.489339885	0.999936032	NA	KLKB1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8586 (FBgn0033320). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:8692796..8696245. It has the cytological map location 44E2. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain. Its molecular function is unknown. It is involved in the biological process described with: proteolysis. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the pupal period.  "
FBgn0039246	CG10845	0.289224361	0.36571452	0.999936032	NA	KIF5B	moderate	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG10845 (FBgn0039246). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:24901116..24903048. It has the cytological map location 96B4-96B5. Protein features are: Kinesin motor domain; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: microtubule binding; ATP binding. It is involved in the biological process described with: . 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die during embryonic stage; viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed in adult male stages.
FBgn0267087	CR45531	0.289224361	0.36571452	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45531 (FBgn0267087). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is X:6860339..6863235. It has the cytological map location 6D7-6D8. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available.
FBgn0083984	CG34148	0.289892496	0.459080019	0.999936032	C15orf61	C15orf61	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG34148 (FBgn0083984). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:21877870..21878686. It has the cytological map location 93F14. Protein features are: Protein of unknown function DUF4528. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, in adult female stages.  "
FBgn0034569	dgt3	0.290097784	0.471827517	0.999936032	NA	NA	NA	NA	NA	NA	"The gene dim ‘_-tubulin 3 is referred to in FlyBase by the symbol Dmel\dgt3 (CG3221, FBgn0034569). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:20992276..20994381. It has the cytological map location 57B5. Protein features are: HAUS augmin-like complex subunit 3, N-terminal. Its molecular function is unknown. It is involved in the biological process described with: regulation of mitotic nuclear division; mitotic spindle organization. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0038881	CG16791	0.290248294	0.461533133	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG16791 (FBgn0038881). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 3R:21318300..21349601. It has the cytological map location 93D5-93D6. Protein features are: WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. It is involved in the biological process described with: phagocytosis. 14 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 06-12 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0001226	Hsp27	0.29027823	0.480718007	0.999936032	NA	HSPB2;HSPB8;HSPB1;HSPB3;CRYAB;HSPB7;HSPB6;CRYAA	high;low;low;moderate;low;moderate;low;low	NA	NA	NA	"The gene Heat shock protein 27 is referred to in FlyBase by the symbol Dmel\Hsp27 (CG4466, FBgn0001226). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:9384063..9385694. It has the cytological map location 67B3. Protein features are: Alpha crystallin/Heat shock protein; Alpha crystallin/Hsp20 domain; HSP20-like chaperone; Small heat shock protein HSP20. Its molecular function is described by: unfolded protein binding; protein binding. It is involved in the biological process described with: defense response to fungus; response to heat; defense response to bacterium; protein refolding; determination of adult lifespan; chaperone-mediated protein folding; behavioral response to starvation. 23 alleles are reported. The phenotypes of these alleles manifest in: ommatidium; trichogen cell; eye. The phenotypic classes of alleles include: immune response defective; visible; viable; phenotype; fertile; stress response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of moderate expression.  Peak expression observed during early pupal stages.  "
FBgn0030913	CG6123	0.290316754	0.393522287	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6123 (FBgn0030913). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:18322958..18356191. It has the cytological map location 17A5-17A6. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.  "
FBgn0003380	Sh	0.290613146	0.489248916	0.999936032	NA	KCNA1;KCNA2;KCNA3;KCNA5;KCNA7;KCNA10;KCNA4;KCNA6	high;moderate;moderate;moderate;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene Shaker is referred to in FlyBase by the symbol Dmel\Sh (CG12348, FBgn0003380). It is a protein_coding_gene from Drosophila melanogaster. It has 15 annotated transcripts and 15 polypeptides (11 unique). Gene sequence location is X:17924307..18063247. It has the cytological map location 16F3-16F6. Protein features are: BTB/POZ domain; Ion transport domain; Potassium channel tetramerisation-type BTB domain; Potassium channel, voltage dependent, Kv; Potassium channel, voltage dependent, Kv1; Potassium channel, voltage dependent, Kv1.1; SKP1/BTB/POZ domain; Voltage-gated potassium channel. Its molecular function is described by: voltage-gated potassium channel activity; voltage-gated cation channel activity. It is involved in the biological process described with 20 unique terms, many of which group under: transport; regulation of membrane potential; multi-organism process; localization; mating behavior; cellular response to organic substance; metal ion transport; response to abiotic stimulus; sensory perception of taste; protein complex biogenesis; growth; proboscis extension reflex. 76 alleles are reported. The phenotypes of these alleles manifest in: larva; synapse; photoreceptor; sense organ; muscle cell; non-connected developing system; adult cuticle; adult central nervous system; neuromuscular junction; end plate. The phenotypic classes of alleles include: phenotype; visible; behavior defective; sensory perception defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed during late pupal stages.  "
FBgn0035437	Strip	0.290627068	0.444473651	0.999936032	NA	STRIP1;STRIP2	high;moderate	NA	NA	NA	"The gene Striatin interacting protein is referred to in FlyBase by the symbol Dmel\Strip (CG11526, FBgn0035437). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:3322025..3328871. It has the cytological map location 63D1. Protein features are: Armadillo-like helical; N1221-like; Protein of unknown function DUF3402. Its molecular function is described by: . It is involved in the biological process described with: endosome organization; negative regulation of synaptic growth at neuromuscular junction; negative regulation of hippo signaling; microtubule cytoskeleton organization; axon extension; positive regulation of ERK1 and ERK2 cascade; positive regulation of Ras protein signal transduction. 17 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval neuromuscular junction; lateral horn; axon; dendrite; antennal lobe projection neuron; actin filament; adult antennal lobe projection neuron DL1 adPN; NMJ bouton; mushroom body; alpha/beta Kenyon cell. The phenotypic classes of alleles include: increased mortality; lethal; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0053057	CG33057	0.290687909	0.482616269	0.999936032	TRPT1	TRPT1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG33057 (FBgn0053057). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:8402168..8405277. It has the cytological map location 66C11. Protein features are: Phosphotransferase KptA/Tpt1. Its molecular function is described by: transferase activity, transferring phosphorus-containing groups. It is involved in the biological process described with: tRNA splicing, via endonucleolytic cleavage and ligation. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; female sterile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult male stages.  "
FBgn0000426	SmF	0.290917757	0.430248654	0.999936032	NA	SNRPF	high	NA	NA	NA	"The gene Small ribonucleoprotein particle protein SmF is referred to in FlyBase by the symbol Dmel\SmF (CG16792, FBgn0000426). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:12183844..12184310. It has the cytological map location 48E6-48E7. Protein features are: LSM domain; LSM domain, eukaryotic/archaea-type; Sm-like protein Lsm6/SmF; Small nuclear ribonucleoprotein F. Its molecular function is described by: RNA binding. It is involved in the biological process described with: spliceosomal snRNP assembly; mRNA splicing, via spliceosome. 5 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0030293	CG1737	0.290955328	0.451857557	0.999936032	NA	VGLL4	low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1737 (FBgn0030293). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:11350608..11355539. It has the cytological map location 10B3-10B4. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; female fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, in adult female stages.  "
FBgn0086901	cv-c	0.291367853	0.420026981	0.999936032	NA	DLC1;STARD13;STARD8	high;moderate;moderate	NA	NA	NA	NA
FBgn0031895	CG4497	0.291420205	0.484983559	0.999936032	NA	FAM122A;FAM122B;FAM122C	high;high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4497 (FBgn0031895). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:7190431..7194588. It has the cytological map location 27E4. Protein features are: FAM122. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0024841	Pcd	0.291538851	0.436295791	0.999936032	NA	PCBD1;PCBD2	high;moderate	NA	NA	NA	"The gene pterin-4a-carbinolamine dehydratase is referred to in FlyBase by the symbol Dmel\Pcd (CG1963, FBgn0024841). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:29723163..29724226. It has the cytological map location 99B9. Protein features are: Transcriptional coactivator/pterin dehydratase. Its molecular function is described by: 4-alpha-hydroxytetrahydrobiopterin dehydratase activity. It is involved in the biological process described with: tetrahydrobiopterin biosynthetic process. 8 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: partially lethal - majority die; visible; viable; lethal - all die during P-stage; lethal; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed during late larval stages, at stages throughout the pupal period.  "
FBgn0022768	Pp2C1	0.29155605	0.469094493	0.999936032	NA	PPM1D	high	NA	NA	NA	"The gene Protein phosphatase 2C is referred to in FlyBase by the symbol Dmel\Pp2C1 (CG2984, FBgn0022768). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:4679988..4686903. It has the cytological map location 4C12-4C13. Protein features are: Fumarate reductase/succinate dehydrogenase, FAD-binding site; PPM-type phosphatase domain; PPM-type phosphatase, divalent cation binding; Protein phosphatase 2C family; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: protein serine/threonine phosphatase activity; cation binding; oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process; protein dephosphorylation. 8 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; female semi-sterile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0002924	ncd	0.291603069	0.486149753	0.999936032	NA	KIFC1;KIFC3	high;moderate	NA	NA	NA	"The gene non-claret disjunctional is referred to in FlyBase by the symbol Dmel\ncd (CG7831, FBgn0002924). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:29804290..29807127. It has the cytological map location 99C1. Protein features are: Kinesin motor domain; Kinesin motor domain, conserved site; P-loop containing nucleoside triphosphate hydrolase; Spindle pole body-associated protein Vik1/Cik1, microtubule binding domain. Its molecular function is described by: ATPase activity; ATP binding; protein homodimerization activity; microtubule motor activity; ATP-dependent microtubule motor activity, minus-end-directed; microtubule binding. It is involved in the biological process described with 16 unique terms, many of which group under: movement of cell or subcellular component; RNA localization; organic substance transport; microtubule-based movement; localization; mitotic centrosome separation; establishment of RNA localization; microtubule bundle formation; female meiotic nuclear division; centrosome cycle; macromolecule localization; minus-end directed microtubule sliding. 38 alleles are reported. The phenotypes of these alleles manifest in: oocyte; spindle; mitotic cell cycle; aster; brain; cytoplasmic microtubule; S2 cell-line. The phenotypic classes of alleles include: mitotic cell cycle defective; lethal - all die before end of embryonic stage; increased mortality; cell cycle defective; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0032069	LManVI	0.291754559	0.379564337	0.999936032	NA	MAN2B1;MAN2B2	moderate;moderate	NA	NA	NA	"The gene Lysosomal ‘±-mannosidase VI is referred to in FlyBase by the symbol Dmel\LManVI (CG9468, FBgn0032069). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:8777661..8781252. It has the cytological map location 29F1. Protein features are: Galactose mutarotase-like domain; Glycoside hydrolase 38/57, N-terminal domain; Glycoside hydrolase families 57/38, central domain; Glycoside hydrolase family 38, N-terminal domain; Glycoside hydrolase family 38, central domain; Glycoside hydrolase/deacetylase, beta/alpha-barrel; Glycosyl hydrolase family 38, C-terminal. Its molecular function is described by: alpha-mannosidase activity; carbohydrate binding. It is involved in the biological process described with: mannose metabolic process; protein deglycosylation. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0034908	CG5543	0.291837608	0.463038953	0.999936032	NA	WDR70	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5543 (FBgn0034908). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:23809236..23811398. It has the cytological map location 60A2. Protein features are: WD40 repeat; WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; embryonic/larval neuroblast. The phenotypic classes of alleles include: neuroanatomy defective; partially lethal - majority die; lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0011236	ken	0.292172443	0.486079624	0.999936032	NA	ZSCAN16;ZNF174	low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene ken and barbie is referred to in FlyBase by the symbol Dmel\ken (CG5575, FBgn0011236). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:23870273..23877442. It has the cytological map location 60A6-60A7. Protein features are: BTB/POZ domain; SKP1/BTB/POZ domain; Zinc finger C2H2-type. Its molecular function is described by: DNA binding; transcription factor activity, sequence-specific DNA binding. It is involved in the biological process described with: copulation; phagocytosis; insemination; male analia development; regulation of JAK-STAT cascade; female analia development; regulation of transcription, DNA-templated; male genitalia development; female genitalia development. 36 alleles are reported. The phenotypes of these alleles manifest in: adult antennal segment; eo-type sensillum; vagina; sensory organ cell; adult external head; wing margin; antenna; rhabdomere R7; early extended germ band embryo; procephalic segment; dorsal closure embryo; mesothoracic segment. The phenotypic classes of alleles include: phenotype; increased mortality during development; lethal - all die before end of P-stage; lethal - all die before end of pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 12-18 embryonic stages.  "
FBgn0039019	HP1c	0.292194267	0.422664368	0.999936032	NA	CBX3;CBX1	moderate;low	Chromatin regulation	NA	NA	"The gene Heterochromatin Protein 1c is referred to in FlyBase by the symbol Dmel\HP1c (CG6990, FBgn0039019). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:22745620..22746605. It has the cytological map location 94C4. Protein features are: Chromo domain; Chromo domain subgroup; Chromo domain, conserved site; Chromo domain-like; Chromo shadow domain; Chromo/chromo shadow domain. Its molecular function is described by: methylated histone binding; protein binding; chromatin binding. It is involved in the biological process described with: regulation of transcription from RNA polymerase II promoter; positive regulation of chromatin silencing at telomere. 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0032733	CG15170	0.292288991	0.394079129	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15170 (FBgn0032733). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:18988268..18990233. It has the cytological map location 37B8. Protein features are: Domain of unknown function DUF753. Its molecular function is unknown. It is involved in the biological process described with: wound healing. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0033051	Strica	0.29253595	0.410370176	0.999936032	NA	CASP6;CASP9;CASP16P	moderate;low;moderate	NA	NA	NA	"The gene Ser/Thr-rich caspase is referred to in FlyBase by the symbol Dmel\Strica (CG7863, FBgn0033051). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:6020311..6023144. It has the cytological map location 42A8. Protein features are: Caspase DECAY; Caspase-like domain; Peptidase C14,  p20 domain; Peptidase C14, caspase non-catalytic subunit p10; Peptidase C14A, caspase catalytic domain. Its molecular function is described by: cysteine-type endopeptidase activity involved in apoptotic process; cysteine-type endopeptidase activity. It is involved in the biological process described with: salivary gland histolysis; programmed cell death; proteolysis; larval midgut histolysis; positive regulation of compound eye retinal cell programmed cell death; nurse cell apoptotic process. 15 alleles are reported. The phenotypes of these alleles manifest in: peptidergic neuron; inter-ommatidial precursor cell; egg chamber; eye; salivary gland. The phenotypic classes of alleles include: visible; viable; fertile; neuroanatomy defective; cell death defective; decreased cell death. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed during early pupal stages.  "
FBgn0003175	px	0.292796975	0.424445927	0.999936032	NA	NA	NA	NA	NA	NA	"The gene plexus is referred to in FlyBase by the symbol Dmel\px (CG4444, FBgn0003175). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 2R:22494297..22562065. It has the cytological map location 58E4-58E8. Protein features are: Armadillo-like helical; Histone deacetylase superfamily. Its molecular function is unknown. It is involved in the biological process described with: imaginal disc-derived wing vein morphogenesis; inter-male aggressive behavior. 61 alleles are reported. The phenotypes of these alleles manifest in: leg; eye; wing; wing vein. The phenotypic classes of alleles include: behavior defective; wild-type; visible; viable; lethal; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis.  "
FBgn0262880	CG43235	0.292808624	0.348382169	0.999936032	NA	CPA2;CPA5;CPA1;CPA4	moderate;moderate;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG43235 (FBgn0262880). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:7693030..7693821. It has the cytological map location 28C1. Protein features are: Carboxypeptidase, activation peptide; Protease propeptides/proteinase inhibitor I9. Its molecular function is described by: metallocarboxypeptidase activity. It is involved in the biological process described with: proteolysis. No alleles are reported."
FBgn0035334	CG8993	0.292941705	0.399063885	0.999936032	TXN2	TXN2	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8993 (FBgn0035334). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:2372199..2372876. It has the cytological map location 62D7. Protein features are: Thioredoxin; Thioredoxin domain; Thioredoxin-like fold. Its molecular function is described by: protein disulfide oxidoreductase activity; disulfide oxidoreductase activity. It is involved in the biological process described with: cellular response to DNA damage stimulus; cell redox homeostasis; glycerol ether metabolic process. 3 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0026149	BCL7-like	0.293449868	0.47636505	0.999936032	NA	BCL7A;BCL7B;BCL7C	high;moderate;moderate	NA	NA	NA	"The gene BCL7-like is referred to in FlyBase by the symbol Dmel\BCL7-like (CG17252, FBgn0026149). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:9356634..9358594. It has the cytological map location 8D9. Protein features are: BCL7. Its molecular function is described by: . It is involved in the biological process described with: . 9 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: flightless; fertile; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, in adult female stages.  "
FBgn0085423	CG34394	0.293485062	0.404860962	0.999936032	NA	GRAMD1B;GRAMD1A;GRAMD1C;GRAMD3	high;moderate;moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG34394 (FBgn0085423). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (all unique). Gene sequence location is 2L:3358640..3373372. It has the cytological map location 23E5-23E6. Protein features are: GRAM domain; VASt domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; some die during pupal stage; lethal - all die before end of pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0039451	CG6420	0.293754383	0.458843136	0.999936032	WDR20	WDR20;DMWD	high;moderate	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG6420 (FBgn0039451). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:26719847..26725216. It has the cytological map location 97C5. Protein features are: WD40 repeat; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: . It is involved in the biological process described with: protein deubiquitination. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0053111	CG33111	0.293865744	0.423326514	0.999936032	NA	SHTN1;DCTN1	low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG33111 (FBgn0053111). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is 3R:23801714..23819237. It has the cytological map location 95B7-95C1. Its molecular function is unknown. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 12-18 embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0032596	Prosbeta4	0.293964717	0.383952658	0.999936032	NA	PSMB2	high	NA	NA	NA	"The gene Proteasome ‘_4 subunit is referred to in FlyBase by the symbol Dmel\Pros‘_4 (CG17331, FBgn0032596). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:16731180..16732133. It has the cytological map location 36A12. Protein features are: Nucleophile aminohydrolases, N-terminal; Proteasome B-type subunit; Proteasome beta-type subunit, conserved site; Proteasome subunit beta 2; Proteasome, subunit alpha/beta. Its molecular function is described by: endopeptidase activity; threonine-type endopeptidase activity. It is involved in the biological process described with: cellular response to DNA damage stimulus; multicellular organism reproduction; proteasome-mediated ubiquitin-dependent protein catabolic process. 6 alleles are reported. The phenotypes of these alleles manifest in: Z disc; sarcomere. The phenotypic classes of alleles include: lethal; fertile; lethal - all die during larval stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in adult female stages.  "
FBgn0028544	CG16884	0.293979768	0.228716514	0.999936032	NA	GGN;TPRX1;ZNF512B	low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG16884 (FBgn0028544). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:13944756..13947476. It has the cytological map location 34E4. Its molecular function is unknown. It is involved in the biological process described with: wing disc development. 4 alleles are reported. The phenotypes of these alleles manifest in: wing vein L4; posterior crossvein; anterior crossvein; wing; wing cell; wing vein L3. The phenotypic classes of alleles include: size defective; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very low expression.  Peak expression observed during early larval stages, during late pupal stages.  "
FBgn0039091	CG10182	0.294274584	0.41129536	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10182 (FBgn0039091). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:23587120..23589819. It has the cytological map location 95A2-95A3. Protein features are: Acyltransferase 3; Nose resistant-to-fluoxetine protein, N-terminal. Its molecular function is described by: transferase activity, transferring acyl groups other than amino-acyl groups. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0040733	CG15068	0.29429306	0.379078435	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG15068 (FBgn0040733). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:18390353..18390629. It has the cytological map location 55C4. Protein features are: Immune-induced protein Dim. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed in adult male stages.
FBgn0053493	CG33493	0.29429306	0.379078435	0.999936032	NA	NDUFA5	low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG33493 (FBgn0053493). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:10692530..10693167. It has the cytological map location 67E7. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0263446	CR43469	0.29429306	0.379078435	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR43469 (FBgn0263446). It is a non_protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts. Gene sequence location is 2R:12872756..12875087. It has the cytological map location 49D6. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0036891	CG9372	0.294523921	0.433177688	0.999936032	NA	PRSS12;CTRB1;CELA3A;CELA1;CTRB2;CELA2A;CTRC;CELA3B;CELA2B;CTRL;PROZ	low;low;low;low;low;low;low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9372 (FBgn0036891). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:19606208..19608368. It has the cytological map location 76B9. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Proteinase, regulatory CLIP domain; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: response to fungus; neuron projection morphogenesis; proteolysis. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the pupal period.  "
FBgn0263258	chas	0.294545379	0.480548751	0.999936032	NA	NA	NA	NA	NA	NA	"The gene chascon is referred to in FlyBase by the symbol Dmel\chas (CG32556, FBgn0263258). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is X:17672458..17698730. It has the cytological map location 16B12-16C1. Its molecular function is described by: . It is involved in the biological process described with: establishment of body hair or bristle planar orientation. 20 alleles are reported. The phenotypes of these alleles manifest in: chaeta; mesothoracic tergum; wing vein; wing; trichome; wing hair; trichogen cell; embryonic/larval hemocyte. The phenotypic classes of alleles include: fertile; viable; visible; planar polarity defective."
FBgn0036544	sff	0.294689729	0.419545794	0.999936032	BRSK2	BRSK1;BRSK2	high;moderate	NA	NA	NA	"The gene sugar-free frosting is referred to in FlyBase by the symbol Dmel\sff (CG6114, FBgn0036544). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3L:15900156..15924861. It has the cytological map location 72A4-72B1. Protein features are: Protein kinase domain; Protein kinase, ATP binding site; Protein kinase-like domain; Serine/threonine-protein kinase, active site. Its molecular function is described by: ATP binding; protein serine/threonine kinase activity. It is involved in the biological process described with: protein phosphorylation; intracellular signal transduction; neuromuscular junction development; protein N-linked glycosylation. 11 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval neuromuscular junction; embryonic/larval hemocyte. The phenotypic classes of alleles include: viable; partially lethal - majority live; gravitaxis defective; some die during pupal stage; lethal - all die before end of pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages.  "
FBgn0054031	CG34031	0.294689729	0.419545794	0.999936032	NA	NKX1-1;HLX;TLX2;LBX2;BARX2;TLX1;DBX1;LBX1;DBX2;TLX3;BARHL2;BARX1;BARHL1	low;low;low;low;low;low;low;low;low;low;low;low;low	DNA-binding with transcription factor activity	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG34031 (FBgn0054031). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:23174446..23185750. It has the cytological map location 80D4. Protein features are: Homeobox domain; Homeobox domain, metazoa; Homeobox domain-like; Homeobox, conserved site. Its molecular function is described by: sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated. 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages.  "
FBgn0264908	pHCl-1	0.294689729	0.419545794	0.999936032	NA	GLRA4;GLRB	moderate;moderate	NA	transmembrane protein	NA	"The gene pH-sensitive chloride channel 1 is referred to in FlyBase by the symbol Dmel\pHCl-1 (CG44099, FBgn0264908). It is a protein_coding_gene from Drosophila melanogaster. It has 16 annotated transcripts and 16 polypeptides (all unique). Gene sequence location is 3L:15848578..15899029. It has the cytological map location 72A2. Protein features are: Gamma-aminobutyric acid A receptor/Glycine receptor alpha; Neurotransmitter-gated ion-channel; Neurotransmitter-gated ion-channel ligand-binding domain; Neurotransmitter-gated ion-channel transmembrane domain. Its molecular function is described by: extracellular ligand-gated ion channel activity; pH-gated chloride channel activity. It is involved in the biological process described with: chloride transmembrane transport. 15 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval neuroblast; ganglion mother cell. The phenotypic classes of alleles include: increased mortality; phenotype; increased mortality during development; lethal - all die before end of P-stage."
FBgn0053052	CG33052	0.294714893	0.473397504	0.999936032	NA	GORAB	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG33052 (FBgn0053052). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:17427305..17428836. It has the cytological map location 74B4-74B5. Protein features are: RAB6-interacting golgin. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: short lived; viable. Summary of modENCODE Temporal Expression Profile:  No temporal expression data available due to processing error.  This will be corrected the next time these data and summaries are processed.
FBgn0031432	Cyp309a1	0.294760474	0.384261743	0.999936032	NA	CYP3A43;CYP3A4;CYP3A5;TBXAS1;CYP3A7-CYP3A51P	moderate;moderate;moderate;moderate;low	NA	transmembrane protein	NA	"The gene Cyp309a1 is referred to in FlyBase by the symbol Dmel\Cyp309a1 (CG9964, FBgn0031432). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:2562483..2564830. It has the cytological map location 22F4-23A1. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Its molecular function is described by: oxidoreductase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; iron ion binding; heme binding. It is involved in the biological process described with: lateral inhibition; oxidation-reduction process. 3 alleles are reported. The phenotypes of these alleles manifest in: chaeta; eye. The phenotypic classes of alleles include: lethal; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during early pupal stages.  "
FBgn0259708	CG42362	0.294765573	0.45246534	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG42362 (FBgn0259708). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:21664126..21666108. It has the cytological map location 57F7. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of very low expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0259709	CG42363	0.294765573	0.45246534	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG42363 (FBgn0259709). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:21664126..21666108. It has the cytological map location 57F7. Its molecular function is described by: . It is involved in the biological process described with: . One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of very low expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0264439	CR43857	0.294831085	0.478887392	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR43857 (FBgn0264439). It is a non_protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts. Gene sequence location is 2L:7423820..7425932. It has the cytological map location 27F4. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0036814	CG14073	0.294968829	0.457734683	0.999936032	NA	BCORL1;BCOR	high;high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14073 (FBgn0036814). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:18802265..18820675. It has the cytological map location 75E1. Protein features are: Ankyrin repeat; Ankyrin repeat-containing domain. Its molecular function is described by: . It is involved in the biological process described with: wing disc dorsal/ventral pattern formation. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 and 12-18 hour embryonic stages, during late larval stages, during late pupal stages, in adult female stages.  "
FBgn0067628	CG33331	0.295095587	0.445398005	0.999936032	NA	TAMM41	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG33331 (FBgn0067628). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:14886456..14887739. It has the cytological map location 88D6. Protein features are: Phosphatidate cytidylyltransferase, mitochondrial. Its molecular function is described by: phosphatidate cytidylyltransferase activity. It is involved in the biological process described with: cardiolipin biosynthetic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, during early larval stages, during late pupal stages, in adult female stages.  "
FBgn0030641	CG6299	0.29526754	0.380720404	0.999936032	NA	GLTP;PLEKHA8;PLEKHA3	high;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6299 (FBgn0030641). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is X:15462722..15466812. It has the cytological map location 13C4. Protein features are: Glycolipid transfer protein domain. Its molecular function is described by: intermembrane lipid transfer activity. It is involved in the biological process described with: intermembrane lipid transfer. 3 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; viable; flight defective; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0030239	CG17333	0.295367561	0.38720452	0.999936032	PGLS	PGLS	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17333 (FBgn0030239). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:10847438..10848534. It has the cytological map location 9F5. Protein features are: 6-phosphogluconolactonase, DevB-type; Glucosamine/galactosamine-6-phosphate isomerase. Its molecular function is described by: 6-phosphogluconolactonase activity. It is involved in the biological process described with: carbohydrate metabolic process; pentose-phosphate shunt, oxidative branch. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed during early larval stages.  "
FBgn0020385	pug	0.295396206	0.419710211	0.999936032	MTHFD1	MTHFD1;MTHFD1L	high;moderate	NA	NA	NA	"The gene pugilist is referred to in FlyBase by the symbol Dmel\pug (CG4067, FBgn0020385). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is 3R:10696534..10703316. It has the cytological map location 86C4. Protein features are: Formate-tetrahydrofolate ligase, FTHFS; Formate-tetrahydrofolate ligase, FTHFS, conserved site; NAD(P)-binding domain; P-loop containing nucleoside triphosphate hydrolase; Tetrahydrofolate dehydrogenase/cyclohydrolase; Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site. Its molecular function is described by: methylenetetrahydrofolate dehydrogenase (NADP+) activity; ATP binding; methenyltetrahydrofolate cyclohydrolase activity; formate-tetrahydrofolate ligase activity. It is involved in the biological process described with: 10-formyltetrahydrofolate biosynthetic process; oxidation-reduction process; purine nucleobase biosynthetic process; cellular amino acid biosynthetic process. 20 alleles are reported. The phenotypes of these alleles manifest in: pigment cell; eye. The phenotypic classes of alleles include: wild-type; eye color defective; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed during early larval stages, during early pupal stages.  "
FBgn0085260	CG34231	0.295448807	0.474446386	0.999936032	RBM48	RBM48	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG34231 (FBgn0085260). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:11986008..11987653. It has the cytological map location 48D5. Protein features are: RNA recognition motif domain. Its molecular function is described by: nucleic acid binding. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0030041	CG12116	0.295474249	0.482036317	0.999936032	NA	SPR	moderate	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG12116 (FBgn0030041). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:8467443..8469012. It has the cytological map location 7F1. Protein features are: NAD(P)-binding domain; Short-chain dehydrogenase/reductase SDR. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal; some die during pupal stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the larval period.
FBgn0011291	Taf11	0.295613495	0.459590917	0.999936032	TAF11	TAF11;LOC391742	high;moderate	DNA-binding with transcription factor activity	NA	NA	"The gene TBP-associated factor 11 is referred to in FlyBase by the symbol Dmel\Taf11 (CG4079, FBgn0011291). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:9762424..9763262. It has the cytological map location 30C7. Protein features are: Histone-fold; TAFII28-like protein. Its molecular function is described by: transcription coactivator activity; transcription factor binding; transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly; protein heterodimerization activity. It is involved in the biological process described with: transcription initiation from RNA polymerase II promoter; positive regulation of RNA interference; positive regulation of protein tetramerization. 14 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during pupal stage; partially lethal - majority die; viable; short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during early pupal stages, in adult female stages.  "
FBgn0031145	Ntf-2	0.295990987	0.386287157	0.999936032	NA	NUTF2	high	NA	NA	NA	"The gene Nuclear transport factor-2 is referred to in FlyBase by the symbol Dmel\Ntf-2 (CG1740, FBgn0031145). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is X:21035469..21041467. It has the cytological map location 19E7. Protein features are: NTF2-like domain; Nuclear transport factor 2; Nuclear transport factor 2, eukaryote. Its molecular function is unknown. It is involved in the biological process described with: transport; positive regulation of antimicrobial peptide biosynthetic process. 19 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; eye. The phenotypic classes of alleles include: increased mortality during development; phenotype; increased mortality; some die during larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0266311	CR44976	0.296021264	0.330151089	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44976 (FBgn0266311). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2L:1708452..1709244. It has the cytological map location 22B1. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0037120	CG11247	0.296082877	0.456236017	0.999936032	NA	ZNF639;ZNF410;ZSCAN20;ZNF99;ZNF133;ZNF564	low;low;low;low;low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11247 (FBgn0037120). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3L:21724326..21728806. It has the cytological map location 78E5. Protein features are: Zinc finger C2H2-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: nucleic acid binding. It is involved in the biological process described with: regulation of cell cycle. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0053217	CG33217	0.296374784	0.404973376	0.999936032	NA	PELP1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG33217 (FBgn0053217). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:23126025..23132209. It has the cytological map location 80D2. Protein features are: Armadillo-like helical; Armadillo-type fold. Its molecular function is described by: . It is involved in the biological process described with: . 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal; lethal - all die during embryonic stage; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-18 hour embryonic stages, in adult female stages.  "
FBgn0032910	CG9265	0.296651394	0.478902263	0.999936032	SDR16C5	SDR16C5;HSD17B11;RDH10;DHRS3;HSD17B13	high;moderate;moderate;low;low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG9265 (FBgn0032910). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2L:21057706..21071502. It has the cytological map location 39A1. Protein features are: NAD(P)-binding domain; Short-chain dehydrogenase/reductase SDR. Its molecular function is unknown. The biological processes in which it is involved are not known. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages.
FBgn0036116	CG7888	0.296960879	0.479667518	0.999936032	NA	SLC36A3;SLC36A2;SLC36A1;SLC36A4	moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7888 (FBgn0036116). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:11054035..11059659. It has the cytological map location 68A3. Protein features are: Amino acid transporter, transmembrane domain. Its molecular function is described by: amino acid transmembrane transporter activity. It is involved in the biological process described with: amino acid transmembrane transport. 6 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval hemocyte. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during late pupal stages.  "
FBgn0013531	MED20	0.297057411	0.454398212	0.999936032	NA	MED20	high	Co-factor	NA	NA	"The gene Mediator complex subunit 20 is referred to in FlyBase by the symbol Dmel\MED20 (CG18780, FBgn0013531). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:8071812..8072848. It has the cytological map location 28E1. Protein features are: Mediator complex, subunit Med20. Its molecular function is described by: RNA polymerase II transcription cofactor activity; transcription coactivator activity; protein binding. It is involved in the biological process described with: regulation of transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter. 6 alleles are reported. The phenotype of these alleles manifest in: spermatocyte. The phenotypic classes of alleles include: some die during larval stage; partially lethal; some die during pupal stage; lethal; lethal - all die before end of larval stage; meiotic cell cycle defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0032665	CG15152	0.297077316	0.373924717	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG15152 (FBgn0032665). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:18114547..18115220. It has the cytological map location 36E5. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages.
FBgn0001149	GstD1	0.297161961	0.282045975	0.999936032	NA	GSTT2B;GSTT1;MARS;VARS;GSTT2;EEF1G;EEF1E1	low;low;low;low;low;low;low	NA	NA	NA	"The gene Glutathione S transferase D1 is referred to in FlyBase by the symbol Dmel\GstD1 (CG10045, FBgn0001149). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:12367817..12369268. It has the cytological map location 87B8. Protein features are: Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Thioredoxin-like fold. Its molecular function is described by: DDT-dehydrochlorinase activity; glutathione transferase activity. It is involved in the biological process described with: glutathione metabolic process. 11 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0266742	CR45215	0.297486177	0.433437897	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45215 (FBgn0266742). It is a non_protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts. Gene sequence location is 3R:8316984..8318006. It has the cytological map location 84F11. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0037560	CR18228	0.297521957	0.397032496	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CR18228 (FBgn0037560). It is a pseudogene_attribute from Drosophila melanogaster. It has 2 annotated transcripts. Gene sequence location is 3R:8260706..8261898. It has the cytological map location 84F6. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed during late larval stages, during early pupal stages, in adult male stages.  "
FBgn0050345	CG30345	0.297539573	0.387616668	0.999936032	NA	SLC46A3;SLC46A1;SLC46A2	moderate;high;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG30345 (FBgn0050345). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:9148689..9151892. It has the cytological map location 45A13. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain; Sugar transporter, conserved site. Its molecular function is described by: transporter activity. It is involved in the biological process described with: transmembrane transport. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during late larval stages.  "
FBgn0259982	l(2)35Cc	0.297567379	0.451646415	0.999936032	NA	UXT	high	NA	NA	NA	"The gene lethal (2) 35Cc is referred to in FlyBase by the symbol Dmel\l(2)35Cc (CG15266, FBgn0259982). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:15256581..15257642. It has the cytological map location 35C5. Protein features are: Prefoldin alpha subunit, archaea-type; Prefoldin alpha-like. Its molecular function is described by: unfolded protein binding; RNA polymerase II transcription cofactor activity. It is involved in the biological process described with: protein folding. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0037809	CG12818	0.297698136	0.477073786	0.999936032	LENG1	LENG1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12818 (FBgn0037809). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:10331581..10332695. It has the cytological map location 86A8. Protein features are: CBF1-interacting co-repressor CIR, N-terminal domain. Its molecular function is described by: . It is involved in the biological process described with: lateral inhibition. 5 alleles are reported. The phenotypes of these alleles manifest in: indirect flight muscle; chaeta; myofibril; sarcomere. The phenotypic classes of alleles include: short lived; flightless; visible; viable; locomotor behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period, in adult female stages.  "
FBgn0035235	CG7879	0.297878249	0.478450836	0.999936032	NA	RBM12B;RBM12	high;high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7879 (FBgn0035235). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:1559813..1568608. It has the cytological map location 62A5-62A6. Protein features are: RNA recognition motif domain. Its molecular function is described by: mRNA binding; nucleic acid binding. It is involved in the biological process described with: regulation of alternative mRNA splicing, via spliceosome. 7 alleles are reported. The phenotypes of these alleles manifest in: wing vein; wing. The phenotypic classes of alleles include: viable; visible; fertile; female sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0030985	Obp18a	0.297977785	0.477075574	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Odorant-binding protein 18a is referred to in FlyBase by the symbol Dmel\Obp18a (CG15883, FBgn0030985). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:19135081..19135868. It has the cytological map location 18A3. Protein features are: Pheromone/general odorant binding protein. Its molecular function is described by: odorant binding. It is involved in the biological process described with: sensory perception of chemical stimulus. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; lethal - all die during P-stage; viable; lethal - all die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed in adult male stages.  "
FBgn0034784	CG9826	0.298158724	0.456736422	0.999936032	NA	SLC17A5;SLC17A4;SLC17A3;SLC17A2;SLC17A1;SLC17A6;SLC17A8;SLC17A7	moderate;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9826 (FBgn0034784). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:22840739..22842977. It has the cytological map location 59B2. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain. Its molecular function is described by: transmembrane transporter activity. It is involved in the biological process described with: anion transport; transmembrane transport. 4 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages.  "
FBgn0265829	CR44618	0.298421904	0.423362117	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44618 (FBgn0265829). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2L:10542860..10543522. It has the cytological map location 31F5. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0030159	CG9689	0.298591833	0.311095163	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG9689 (FBgn0030159). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:9881953..9883670. It has the cytological map location 9A3. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late pupal stages.
FBgn0030596	CG12398	0.298591833	0.311095163	0.999936032	NA	CHDH	moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12398 (FBgn0030596). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:14911781..14913812. It has the cytological map location 13A1. Protein features are: FAD/NAD(P)-binding domain; Glucose-methanol-choline oxidoreductase; Glucose-methanol-choline oxidoreductase, C-terminal; Glucose-methanol-choline oxidoreductase, N-terminal. Its molecular function is described by: flavin adenine dinucleotide binding; oxidoreductase activity, acting on CH-OH group of donors; oxidoreductase activity. It is involved in the biological process described with: ecdysteroid metabolic process; oxidation-reduction process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed in adult female stages.  "
FBgn0036927	Gabat	0.298691082	0.457731703	0.999936032	NA	ABAT	high	NA	NA	NA	"The gene ‘_-aminobutyric acid transaminase is referred to in FlyBase by the symbol Dmel\Gabat (CG7433, FBgn0036927). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 3L:19997714..20000686. It has the cytological map location 76D8-76E1. Protein features are: 4-aminobutyrate aminotransferase, eukaryotic; Aminotransferase class-III; Pyridoxal phosphate-dependent transferase; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; Pyridoxal phosphate-dependent transferase, subdomain 2. Its molecular function is described by: 4-aminobutyrate transaminase activity; pyridoxal phosphate binding. It is involved in the biological process described with: gamma-aminobutyric acid metabolic process; cellular amino acid metabolic process; regulation of carbohydrate metabolic process; regulation of circadian sleep/wake cycle; regulation of glutamate metabolic process. 12 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: sleep defective; starvation stress response defective; fertile; short lived; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0051121	CG31121	0.298725696	0.389154313	0.999936032	NA	ABCG8;ABCG5	high;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31121 (FBgn0051121). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:24881466..24894605. It has the cytological map location 96B2-96B4. Protein features are: ABC transporter-like; ABC-2 type transporter; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: ATPase activity, coupled to transmembrane movement of substances; ATP binding. The biological processes in which it is involved are not known. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal; fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0261802	CG42748	0.298845247	0.402524296	0.999936032	NA	C9orf172	high	DNA-binding with transcription factor activity	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG42748 (FBgn0261802). It is a protein_coding_gene from Drosophila melanogaster. It has 11 annotated transcripts and 11 polypeptides (10 unique). Gene sequence location is 2L:22131221..22166221. It has the cytological map location 40E5-40F2. Its molecular function is described by: protein phosphatase 1 binding. The biological processes in which it is involved are not known. 39 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval hemocyte. The phenotypic classes of alleles include: fertile; viable.
FBgn0031458	aph-1	0.2989293	0.398470447	0.999936032	NA	APH1B;APH1A	high;high	NA	transmembrane protein	NA	"The gene anterior pharynx defective 1 is referred to in FlyBase by the symbol Dmel\aph-1 (CG2855, FBgn0031458). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:2766233..2767281. It has the cytological map location 23A5. Protein features are: Gamma-secretase subunit Aph-1. Its molecular function is described by: endopeptidase activity. It is involved in the biological process described with: protein processing; regulation of Notch signaling pathway; Notch receptor processing; Notch signaling pathway; positive regulation of catalytic activity. 20 alleles are reported. The phenotypes of these alleles manifest in: microchaeta; eye; tormogen cell; macrochaeta; presumptive embryonic/larval nervous system; embryonic/larval optic lobe; wing. The phenotypic classes of alleles include: increased mortality; phenotype; viable; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during early pupal stages.  "
FBgn0036624	RAF2	0.299130214	0.474176431	0.999936032	NA	ZMYND10	low	NA	NA	NA	"The gene RING-associated factor 2 is referred to in FlyBase by the symbol Dmel\RAF2 (CG4877, FBgn0036624). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3L:16386327..16390816. It has the cytological map location 72E4. Protein features are: Zinc finger, MYND-type. Its molecular function is described by: zinc ion binding; transcription factor activity, sequence-specific DNA binding. It is involved in the biological process described with: regulation of multicellular organismal development; regulation of transcription from RNA polymerase II promoter. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0036210	CG14130	0.299136059	0.436421865	0.999936032	ALKBH7	ALKBH7	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14130 (FBgn0036210). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:11815444..11816710. It has the cytological map location 68E1. Protein features are: Alpha-ketoglutarate-dependent dioxygenase AlkB-like; Alpha-ketoglutarate-dependent dioxygenase alkB homologue 7. Its molecular function is described by: . It is involved in the biological process described with: cellular response to DNA damage stimulus; fatty acid metabolic process; regulation of mitochondrial membrane permeability involved in programmed necrotic cell death. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0032451	spict	0.299501139	0.377493099	0.999936032	NIPA2	NIPA2;NIPAL1;NIPAL4;NIPA1;NIPAL3;NIPAL2	high;moderate;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene spichthyin is referred to in FlyBase by the symbol Dmel\spict (CG12292, FBgn0032451). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:12704725..12706683. It has the cytological map location 33F3. Protein features are: Magnesium transporter NIPA. Its molecular function is described by: magnesium ion transmembrane transporter activity. It is involved in the biological process described with: negative regulation of synaptic growth at neuromuscular junction; negative regulation of BMP signaling pathway; magnesium ion transport; positive regulation of axon extension involved in regeneration. 16 alleles are reported. The phenotypes of these alleles manifest in: posterior crossvein; type I bouton; bouton; axon; wing; embryonic/larval neuromuscular junction; dorsal multidendritic neuron ddaE. The phenotypic classes of alleles include: wound healing defective; size defective; neuroanatomy defective; viable; developmental rate defective; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0032140	CG13117	0.299552413	0.418471206	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG13117 (FBgn0032140). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:9736645..9737949. It has the cytological map location 30C6. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed during early pupal stages.
FBgn0031319	CG4896	0.299563281	0.455423843	0.999936032	RBM10	RBM10;RBM5;RBM6	high;high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4896 (FBgn0031319). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 2L:1177690..1182454. It has the cytological map location 21F2. Protein features are: G-patch domain; RNA recognition motif domain; Zinc finger, RanBP2-type. Its molecular function is described by: RNA binding; mRNA binding. It is involved in the biological process described with: regulation of alternative mRNA splicing, via spliceosome. 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout the pupal period, in adult male stages.  "
FBgn0259171	Pde9	0.299843452	0.421770086	0.999936032	NA	PDE9A	high	NA	NA	NA	"The gene Phosphodiesterase 9 is referred to in FlyBase by the symbol Dmel\Pde9 (CG42276, FBgn0259171). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is X:12785563..12897327. It has the cytological map location 11C4-11D1. Protein features are: 3'5'-cyclic nucleotide phosphodiesterase; 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain; 3'5'-cyclic nucleotide phosphodiesterase, conserved site; HD/PDEase domain. Its molecular function is described by: 3',5'-cyclic-nucleotide phosphodiesterase activity. It is involved in the biological process described with: cyclic nucleotide metabolic process; signal transduction. 13 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; embryonic/larval neuroblast; mesothoracic tergum. The phenotypic classes of alleles include: increased mortality during development; phenotype; increased mortality; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult male stages.  "
FBgn0085478	CG34449	0.300055788	0.437903313	0.999936032	NA	ZDHHC5;ZDHHC8;ZDHHC18;ZDHHC14;ZDHHC9	high;moderate;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG34449 (FBgn0085478). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (all unique). Gene sequence location is X:9324508..9356227. It has the cytological map location 8D7-8D9. Protein features are: Palmitoyltransferase, DHHC domain; Tetratricopeptide-like helical domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: palmitoyltransferase activity. It is involved in the biological process described with: protein palmitoylation. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, in adult female stages.  "
FBgn0000228	Bsg25D	0.30033986	0.438335495	0.999936032	NA	NIN;NINL	high;moderate	NA	NA	NA	"The gene Blastoderm-specific gene 25D is referred to in FlyBase by the symbol Dmel\Bsg25D (CG14025, FBgn0000228). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (all unique). Gene sequence location is 2L:5271728..5278548. It has the cytological map location 25D2-25D3. Its molecular function is described by: microtubule binding. It is involved in the biological process described with: microtubule organizing center attachment site organization. 13 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; lethal - all die during P-stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0001179	hay	0.300625903	0.444128202	0.999936032	NA	ERCC3	high	DNA-binding with transcription factor activity	NA	NA	"The gene haywire is referred to in FlyBase by the symbol Dmel\hay (CG8019, FBgn0001179). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:10631079..10633969. It has the cytological map location 67E5. Protein features are: ERCC3/RAD25/XPB helicase, C-terminal domain; Helicase XPB/Ssl2; Helicase XPB/Ssl2, N-terminal domain; Helicase superfamily 1/2, ATP-binding domain; Helicase, C-terminal; Helicase/UvrB, N-terminal; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: transcription factor activity, core RNA polymerase binding; ATP-dependent 3'-5' DNA helicase activity; DNA binding; ATP binding; helicase activity. It is involved in the biological process described with 11 unique terms, many of which group under: DNA-templated transcriptional open complex formation; regulation of growth; DNA repair; mRNA processing; response to abiotic stimulus; nucleotide-excision repair; transcriptional open complex formation at RNA polymerase II promoter; regulation of binding; cell proliferation; regulation of RNA polymerase II regulatory region sequence-specific DNA binding; cellular response to DNA damage stimulus; protein-DNA complex remodeling; response to UV. 30 alleles are reported. The phenotypes of these alleles manifest in: microchaeta; meiotic cell cycle; chaeta; imaginal disc; macrochaeta; wing margin; wing; embryonic/larval central nervous system. The phenotypic classes of alleles include: sterile; phenotype; increased mortality; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, during early pupal stages, in adult female stages.  "
FBgn0032974	CG3651	0.300865774	0.422952698	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG3651 (FBgn0032974). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:22121338..22126614. It has the cytological map location 40E4. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0086446	DCTN6-p27	0.300880659	0.408434996	0.999936032	NA	DCTN6	high	NA	NA	NA	"The gene Dynactin 6, p27 subunit is referred to in FlyBase by the symbol Dmel\DCTN6-p27 (CG17347, FBgn0086446). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:19132323..19133097. It has the cytological map location 37C1. Protein features are: Dynactin subunit 6; Hexapeptide repeat; Trimeric LpxA-like. Its molecular function is unknown. It is involved in the biological process described with: microtubule-based movement. 17 alleles are reported. The phenotype of these alleles manifest in: melanotic mass. The phenotypic classes of alleles include: lethal; melanotic mass phenotype; wild-type; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0042182	CG18749	0.300905728	0.444810331	0.999936032	NA	P4HA1;P4HA3;P4HA2	moderate;moderate;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG18749 (FBgn0042182). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:8244055..8248054. It has the cytological map location 84F5-84F6. Protein features are: Oxoglutarate/iron-dependent dioxygenase; Prolyl 4-hydroxylase alpha-subunit, N-terminal; Prolyl 4-hydroxylase, alpha subunit; Tetratricopeptide-like helical domain. Its molecular function is described by: procollagen-proline 4-dioxygenase activity; L-ascorbic acid binding; iron ion binding; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. It is involved in the biological process described with: oxidation-reduction process; multicellular organism reproduction. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0261113	Xrp1	0.301062836	0.367293634	0.999936032	NA	NA	NA	DNA-binding with transcription factor activity(AT_hook)	NA	NA	"The gene Xrp1 is referred to in FlyBase by the symbol Dmel\Xrp1 (CG17836, FBgn0261113). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (2 unique). Gene sequence location is 3R:18914968..18926989. It has the cytological map location 91D3-91D5. Its molecular function is described by: protein dimerization activity; P-element binding. It is involved in the biological process described with: double-strand break repair; negative regulation of cell proliferation; olfactory behavior; chromosome organization; cellular process. 40 alleles are reported. The phenotypes of these alleles manifest in: wing; antenna; eye. The phenotypic classes of alleles include: lethal; viable; smell perception defective; visible; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, in adult male stages.  "
FBgn0010314	Cks30A	0.30112598	0.246337789	0.999936032	NA	CKS1B;CKS2	high;moderate	NA	NA	NA	"The gene Cyclin-dependent kinase subunit 30A is referred to in FlyBase by the symbol Dmel\Cks30A (CG3738, FBgn0010314). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:9330763..9331981. It has the cytological map location 30A8. Protein features are: Cyclin-dependent kinase, regulatory subunit. Its molecular function is described by: protein binding; cyclin-dependent protein serine/threonine kinase activator activity; ubiquitin binding; histone binding; protein kinase binding. It is involved in the biological process described with 11 unique terms, many of which group under: mitotic cell cycle; protein catabolic process; imaginal disc morphogenesis; syncytial blastoderm mitotic cell cycle; spindle assembly involved in female meiosis; spindle organization; positive regulation of protein serine/threonine kinase activity; cellular nitrogen compound metabolic process; microtubule-based process; proteolysis; cellular component biogenesis; embryo development; regulation of mitotic cell cycle. 13 alleles are reported. The phenotypes of these alleles manifest in: spindle pole centrosome; embryo; aster; embryonic/first instar larval cuticle; spindle. The phenotypic classes of alleles include: increased mortality during development; phenotype; cell cycle defective; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0034924	CG17658	0.30112598	0.246337789	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17658 (FBgn0034924). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:23895063..23896997. It has the cytological map location 60A9. Protein features are: Zinc finger, MYND-type. Its molecular function is unknown. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0038619	CG7685	0.301564073	0.461672466	0.999936032	NA	PRKCSH	moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7685 (FBgn0038619). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:18404940..18406002. It has the cytological map location 91A6. Protein features are: Glucosidase 2 subunit beta; Glucosidase II beta subunit, N-terminal. Its molecular function is unknown. It is involved in the biological process described with: N-glycan processing. 6 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, during early pupal stages.  "
FBgn0267408	AOX1	0.301646476	0.365812893	0.999936032	NA	AOX1;XDH	low;low	NA	NA	NA	"The gene Aldehyde oxidase 1 is referred to in FlyBase by the symbol Dmel\AOX1 (CG18522, FBgn0267408). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:15532137..15537292. It has the cytological map location 89A1-89A2. Protein features are: 2Fe-2S ferredoxin, iron-sulphur binding site; 2Fe-2S ferredoxin-type iron-sulfur binding domain; Aldehyde oxidase/xanthine dehydrogenase; Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead; Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding; Beta-grasp domain; CO dehydrogenase flavoprotein, C-terminal; CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2; FAD-binding, type 2; FAD-binding, type 2, subdomain 1; Molybdopterin dehydrogenase, FAD-binding; [2Fe-2S]-binding. Its molecular function is described by: xanthine dehydrogenase activity; electron carrier activity; pyridoxal oxidase activity; flavin adenine dinucleotide binding; oxidoreductase activity, acting on CH-OH group of donors; iron ion binding; 2 iron, 2 sulfur cluster binding. It is involved in the biological process described with: oxidation-reduction process; xanthine catabolic process; pyridoxal metabolic process. 8 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: electrophoretic variant."
FBgn0034503	MED8	0.301963914	0.435755021	0.999936032	NA	MED8	high	Co-factor	NA	NA	"The gene Mediator complex subunit 8 is referred to in FlyBase by the symbol Dmel\MED8 (CG13867, FBgn0034503). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:20325844..20326806. It has the cytological map location 56F16. Protein features are: Mediator complex, subunit Med8, fungi/metazoa. Its molecular function is described by: RNA polymerase II transcription cofactor activity. It is involved in the biological process described with: regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; regulation of cell cycle. 4 alleles are reported. The phenotypes of these alleles manifest in: spermatocyte; mesothoracic tergum; chaeta. The phenotypic classes of alleles include: viable; visible; meiotic cell cycle defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.  "
FBgn0000411	D	0.301968035	0.221341932	0.999936032	NA	SOX21;SOX14;SOX12;SOX1;SOX3;SOX4	moderate;low;low;low;low;low	DNA-binding with transcription factor activity(HMG_box)	NA	NA	"The gene Dichaete is referred to in FlyBase by the symbol Dmel\D (CG5893, FBgn0000411). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 3L:14175610..14178620. It has the cytological map location 70D3. Protein features are: High mobility group box domain. Its molecular function is described by: DNA binding, bending; sequence-specific DNA binding; mRNA 3'-UTR binding; transcription factor binding; DNA binding; transcription factor activity, sequence-specific DNA binding; transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding. It is involved in the biological process described with 17 unique terms, many of which group under: post-embryonic development; negative regulation of RNA metabolic process; blastoderm segmentation; embryonic pattern specification; animal organ development; neuroblast development; cellular macromolecule localization; tube development; digestive tract morphogenesis; axis specification. 75 alleles are reported. The phenotypes of these alleles manifest in: cell; plasma membrane bounded cell projection; chorion; eye disc; RP2 motor neuron; cell part; motor neuron; larval abdominal segment 8; embryonic/larval glial cell; pigment cell; abdominal 4 ventral denticle belt; abdominal segment 1. The phenotypic classes of alleles include: short lived; some die during P-stage; phenotype; lethal - all die during P-stage; lethal - all die before end of first instar larval stage; visible; eye color defective; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0030438	CG15721	0.301968035	0.221341932	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG15721 (FBgn0030438). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:12970711..12973967. It has the cytological map location 11D5. Protein features are: Kazal domain. Its molecular function is described by: serine-type endopeptidase inhibitor activity. It is involved in the biological process described with: negative regulation of serine-type endopeptidase activity; chorion-containing eggshell formation. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed in adult female stages.
FBgn0051789	CG31789	0.301968035	0.221341932	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31789 (FBgn0051789). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:18605928..18606684. It has the cytological map location 36F7. Protein features are: Transcription activator MBF2. Its molecular function is described by: . It is involved in the biological process described with: . 5 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum. The phenotypic classes of alleles include: viable; visible; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period, during early pupal stages.  "
FBgn0263132	Cht6	0.301981196	0.347911297	0.999936032	NA	CHIA;CHIT1;OVGP1;CHI3L2;CHI3L1	moderate;moderate;moderate;low;low	NA	NA	NA	"The gene Chitinase 6 is referred to in FlyBase by the symbol Dmel\Cht6 (CG43374, FBgn0263132). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (all unique). Gene sequence location is X:10016845..10050803. It has the cytological map location 9A5. Protein features are: Chitin binding domain; Chitinase II; Chitinase insertion domain; Glycoside hydrolase family 18, catalytic domain; Glycoside hydrolase superfamily; Glycoside hydrolase, chitinase active site. Its molecular function is described by: chitinase activity; chitin binding. It is involved in the biological process described with: carbohydrate metabolic process; ecdysis, chitin-based cuticle; chitin catabolic process. 10 alleles are reported. The phenotypes of these alleles manifest in: pupal cuticle; wing. The phenotypic classes of alleles include: partially lethal; increased mortality; increased mortality during development; phenotype."
FBgn0028699	Rh50	0.302157232	0.460215843	0.999936032	NA	RHBG;RHCG;RHAG;RHCE;RHD	high;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene Rh50 is referred to in FlyBase by the symbol Dmel\Rh50 (CG7499, FBgn0028699). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:4910368..4920198. It has the cytological map location 64C2. Protein features are: Ammonium transporter AmtB-like domain; Blood group Rhesus C/E/D polypeptide. Its molecular function is described by: ammonium transmembrane transporter activity. It is involved in the biological process described with: organic cation transport; ammonium transmembrane transport. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed during early larval stages.  "
FBgn0004598	Fur2	0.302339126	0.47191897	0.999936032	NA	PCSK5;PCSK4;FURIN;PCSK6;PCSK2;PCSK1;PCSK7	high;moderate;moderate;moderate;low;low;low	NA	transmembrane protein	NA	"The gene Furin 2 is referred to in FlyBase by the symbol Dmel\Fur2 (CG18734, FBgn0004598). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (4 unique). Gene sequence location is X:16373086..16381782. It has the cytological map location 14C1-14C2. Protein features are: EGF-like domain; Furin-like repeat; Galactose-binding domain-like; Growth factor receptor cysteine-rich domain; Growth factor receptor domain 4; Kexin/furin catalytic domain; Peptidase S8, pro-domain; Peptidase S8, subtilisin,  Asp-active site; Peptidase S8, subtilisin, His-active site; Peptidase S8, subtilisin, Ser-active site; Peptidase S8, subtilisin-related; Peptidase S8/S53 domain; Proprotein convertase, P; Protease propeptides/proteinase inhibitor I9; Receptor L-domain. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; regulation of glucose metabolic process; negative regulation of secretion. 17 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, in adult female stages.  "
FBgn0004652	fru	0.302397532	0.462385414	0.999936032	NA	ZBTB1;ZBTB45;ZBTB39;ZBTB24	low;low;low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene fruitless is referred to in FlyBase by the symbol Dmel\fru (CG14307, FBgn0004652). It is a protein_coding_gene from Drosophila melanogaster. It has 15 annotated transcripts and 15 polypeptides (13 unique). Gene sequence location is 3R:18414273..18545586. It has the cytological map location 91A7-91B3. Protein features are: BTB/POZ domain; Ribosomal protein S5 domain 2-type fold, subgroup; SKP1/BTB/POZ domain; Zinc finger C2H2-type. Its molecular function is described by: transcription factor activity, sequence-specific DNA binding; nucleic acid binding. It is involved in the biological process described with 22 unique terms, many of which group under: developmental process involved in reproduction; animal organ development; multi-organism reproductive process; regulation of cellular biosynthetic process; mating behavior, sex discrimination; behavior; regulation of cellular metabolic process; cellular component organization; biosynthetic process; aggressive behavior. 118 alleles are reported. The phenotypes of these alleles manifest in: adult fruitless aSP-a (male) neuron; developing embryonic structure; adult fruitless aDT-b (male) neuron; chemosensory neuron; embryonic/larval central nervous system; adult fruitless vAB3 (male) lineage clone; cell component; adult SMPad1 (male) lineage clone; compound sense organ; adult fruitless vPR6 (male) lineage clone; abdomen. The phenotypic classes of alleles include: behavior defective; increased mortality; fertile; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.  "
FBgn0040534	Sf3b5	0.302452988	0.436343376	0.999936032	NA	SF3B5	high	NA	NA	NA	"The gene Splicing factor 3b subunit 5 is referred to in FlyBase by the symbol Dmel\Sf3b5 (CG11985, FBgn0040534). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:9014972..9015341. It has the cytological map location 85C2. Protein features are: Splicing factor 3B subunit 5/RDS3 complex subunit 10; Splicing factor 3B, subunit 5. Its molecular function is described by: . It is involved in the biological process described with: mRNA splicing, via spliceosome; spermatogenesis. 6 alleles are reported. The phenotypes of these alleles manifest in: spermatozoon; eye; Z disc; spermatogonium; sarcomere. The phenotypic classes of alleles include: sterile; phenotype; lethal - all die before end of larval stage; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0031077	THADA	0.302525585	0.468800987	0.999936032	NA	THADA	high	NA	NA	NA	"The gene THADA is referred to in FlyBase by the symbol Dmel\THADA (CG15618, FBgn0031077). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:19859743..19865524. It has the cytological map location 18F4. Protein features are: Armadillo-like helical; Armadillo-type fold; Domain of unknown function DUF2428, death-receptor-like. Its molecular function is described by: ion channel binding. It is involved in the biological process described with: adaptive thermogenesis; negative regulation of calcium-transporting ATPase activity; negative regulation of endoplasmic reticulum calcium ion concentration; negative regulation of lipid storage. 6 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; lipid particle; adult fat body; chaeta. The phenotypic classes of alleles include: lethal; starvation stress response defective; visible; viable; cold stress response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages, during early pupal stages, in adult female stages.  "
FBgn0260634	eIF4G2	0.30259412	0.423144997	0.999936032	NA	EIF4G3;EIF4G1	moderate;moderate	NA	NA	NA	"The gene eukaryotic translation initiation factor 4G2 is referred to in FlyBase by the symbol Dmel\eIF4G2 (CG10192, FBgn0260634). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:23808285..23819237. It has the cytological map location 95B9-95C1. Protein features are: Armadillo-type fold; Initiation factor eIF-4 gamma, MA3; MIF4G-like, type 3; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: RNA 7-methylguanosine cap binding. It is involved in the biological process described with: autophagic cell death; male germ-line cyst formation; spermatid differentiation; salivary gland cell autophagic cell death; male meiotic nuclear division; spermatogenesis; spermatocyte division. 15 alleles are reported. The phenotypes of these alleles manifest in: testis; spermatid; spermatozoon; spermatocyte; elongation stage spermatid; primary spermatocyte; spermatid cyst. The phenotypic classes of alleles include: male fertile; female fertile; meiotic cell cycle defective; male sterile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed at stages throughout the pupal period, in adult male stages.  "
FBgn0052783	CG32783	0.302721285	0.396788801	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG32783 (FBgn0052783). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:3945043..3948460. It has the cytological map location 3F9. Its molecular function is described by: . It is involved in the biological process described with: . One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed in adult male stages.
FBgn0053180	Ranbp16	0.302728658	0.439022803	0.999936032	NA	XPO7;RANBP17	high;moderate	NA	transmembrane protein	NA	"The gene Ranbp16 is referred to in FlyBase by the symbol Dmel\Ranbp16 (CG33180, FBgn0053180). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (5 unique). Gene sequence location is X:15927185..15933867. It has the cytological map location 14A1. Protein features are: Armadillo-like helical; Armadillo-type fold; Importin-beta, N-terminal domain. Its molecular function is described by: Ran GTPase binding; nuclear export signal receptor activity. It is involved in the biological process described with: protein export from nucleus. 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0002973	numb	0.302940855	0.396784996	0.999936032	NA	NUMBL;NUMB	high;moderate	NA	NA	NA	"The gene numb is referred to in FlyBase by the symbol Dmel\numb (CG3779, FBgn0002973). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:9437469..9464184. It has the cytological map location 30B3-30B5. Protein features are: NUMB domain; Numb/numb-like; PH domain-like; PTB/PI domain. Its molecular function is described by: Notch binding; protein binding. It is involved in the biological process described with 29 unique terms, many of which group under: organic substance metabolic process; regulation of localization; muscle cell fate commitment; cellular localization; stem cell fate determination; rhythmic behavior; macromolecule localization; behavior; neuroblast fate commitment; microtubule organizing center localization; cellular component organization or biogenesis; Malpighian tubule tip cell differentiation; protein localization; stem cell differentiation; macromolecule metabolic process; muscle structure development; rhythmic process. 97 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval glial cell; adult somatic muscle; organelle part; type I neuroblast; abdominal 7 ventral acute muscle 1; dorsal abdominal cluster; abdominal 6 ventral adult muscle precursor cell; neuroblast of ventral nerve cord primordium; abdominal 7 lateral longitudinal muscle 1; serotonergic abdominal medial neuron; dorsal closure embryo; aCC neuron; abdominal 7 dorsal oblique muscle 5. The phenotypic classes of alleles include: cell number defective; cell death defective; size defective; lethal; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0034314	nopo	0.303111357	0.468630861	0.999936032	NA	TRAIP	high	NA	NA	NA	"The gene no poles is referred to in FlyBase by the symbol Dmel\nopo (CG5140, FBgn0034314). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:18180496..18182519. It has the cytological map location 55B12. Protein features are: Zinc finger, RING-CH-type; Zinc finger, RING-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: zinc ion binding; DNA polymerase binding; ubiquitin-protein transferase activity; ubiquitin conjugating enzyme binding. It is involved in the biological process described with: positive regulation of mitotic cell cycle, embryonic; cell death; protein ubiquitination. 9 alleles are reported. The phenotypes of these alleles manifest in: centrosome; eye; wing margin; spindle; mitotic spindle. The phenotypic classes of alleles include: partially lethal; some die during embryonic stage; increased mortality during development; phenotype; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0011202	dia	0.303184137	0.395291922	0.999936032	NA	DIAPH2;DIAPH3;DIAPH1;GRID2IP	high;moderate;moderate;moderate	NA	NA	NA	"The gene diaphanous is referred to in FlyBase by the symbol Dmel\dia (CG1768, FBgn0011202). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is 2L:20758144..20768053. It has the cytological map location 38E7-38E8. Protein features are: Armadillo-like helical; Armadillo-type fold; DRF autoregulatory; Diaphanous autoregulatory (DAD) domain; Formin, FH2 domain; Formin, FH3 domain; Formin, GTPase-binding domain; Formin, protein diaphanous; Rho GTPase-binding/formin homology 3 (GBD/FH3) domain. Its molecular function is described by: protein binding; phosphatidylinositol-4,5-bisphosphate binding; Rho GTPase binding; actin binding. It is involved in the biological process described with 26 unique terms, many of which group under: sensory perception of mechanical stimulus; salivary gland morphogenesis; phenol-containing compound metabolic process; maintenance of protein location; respiratory system development; endomembrane system organization; regulation of response to stimulus; spermatogenesis; sensory perception; animal organ morphogenesis; positive regulation of wound healing; plasma membrane organization; immune system process. 44 alleles are reported. The phenotypes of these alleles manifest in: plasma membrane bounded cell projection; cell projection; spermatocyte cyst; germ layer; compound sense organ; stage 7 embryo; trichome field; somatic cell of testis; embryonic/larval trachea; morphogenetic furrow; eo-type sensillum. The phenotypic classes of alleles include: increased mortality; male sterile; phenotype; lethal - all die before end of embryonic stage; immune response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0027553	NELF-B	0.303289018	0.439652202	0.999936032	NA	NELFB	high	Maybe TF	NA	NA	"The gene NELF-B is referred to in FlyBase by the symbol Dmel\NELF-B (CG32721, FBgn0027553). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:7725996..7728361. It has the cytological map location 7B7. Protein features are: Cofactor of BRCA1. Its molecular function is described by: RNA binding. It is involved in the biological process described with: negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter during mitotic cell cycle; negative regulation of transcription elongation from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter. 8 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: visible; viable; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0033224	Nop17l	0.303312198	0.395300529	0.999936032	NA	DNAAF2;PIH1D1;PIH1D2	high;moderate;low	NA	NA	NA	"The gene Nop17 like is referred to in FlyBase by the symbol Dmel\Nop17l (CG1553, FBgn0033224). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:7800785..7806385. It has the cytological map location 43E17-43E18. Protein features are: Kintoun; PIH1 domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: protein phosphatase 1 binding. It is involved in the biological process described with: axonemal dynein complex assembly. 9 alleles are reported. The phenotypes of these alleles manifest in: posterior wing margin; wing. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0031006	rictor	0.303577758	0.466014465	0.999936032	NA	RICTOR	high	NA	NA	NA	"The gene rapamycin-insensitive companion of Tor is referred to in FlyBase by the symbol Dmel\rictor (CG8002, FBgn0031006). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is X:19252111..19261240. It has the cytological map location 18B6. Protein features are: Armadillo-like helical; Armadillo-type fold; Pianissimo family; Rapamycin-insensitive companion of mTOR, N-terminal domain; Rapamycin-insensitive companion of mTOR, domain 4; Rapamycin-insensitive companion of mTOR, domain 5; Rapamycin-insensitive companion of mTOR, middle domain. Its molecular function is described by: enzyme activator activity. It is involved in the biological process described with 14 unique terms, many of which group under: cellular response to stimulus; regulation of signal transduction; cellular response to DNA damage stimulus; regulation of cellular metabolic process; establishment of cell polarity; cellular response to starvation; ribonucleoprotein complex assembly; establishment or maintenance of cell polarity; ribonucleoprotein complex subunit organization; cell morphogenesis involved in neuron differentiation; phosphate-containing compound metabolic process; synapse assembly; regulation of cell communication; regulation of biological quality. 21 alleles are reported. The phenotypes of these alleles manifest in: cell part; neuron part; cell projection; dorsal multidendritic neuron; abdominal sensory neuron; thorax; dendritic tree; embryonic/larval thoracic/abdominal dorsal sensory cluster; macromolecular complex; anatomical space; abdominal ventral multidendritic neuron; pupa. The phenotypic classes of alleles include: neuroanatomy defective; increased mortality during development; viable; temperature response defective; phenotype; visible; developmental rate defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, in adult female stages.  "
FBgn0030048	CG12112	0.304025026	0.407436739	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12112 (FBgn0030048). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:8558879..8560192. It has the cytological map location 7F4. Protein features are: Domain of unknown function DUF4806. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0036419	CG13482	0.304641073	0.364111118	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13482 (FBgn0036419). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:14329346..14329885. It has the cytological map location 70D5. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during early pupal stages, in adult male stages.  "
FBgn0003870	ttk	0.30495223	0.412911088	0.999936032	NA	ZBTB45;ZBTB24;ZBTB9	low;low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene tramtrack is referred to in FlyBase by the symbol Dmel\ttk (CG1856, FBgn0003870). It is a protein_coding_gene from Drosophila melanogaster. It has 8 annotated transcripts and 8 polypeptides (2 unique). Gene sequence location is 3R:31713867..31735392. It has the cytological map location 100D1. Protein features are: BTB/POZ domain; SKP1/BTB/POZ domain; Zinc finger C2H2-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: chromatin binding; protein binding; promoter-specific chromatin binding; transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding; DNA binding; POZ domain binding; protein homodimerization activity; RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II distal enhancer sequence-specific DNA binding. It is involved in the biological process described with 25 unique terms, many of which group under: morphogenesis of an epithelium; open tracheal system development; negative regulation of gene expression; compound eye corneal lens development; aggressive behavior; transcription from RNA polymerase II promoter; regulation of molecular function; cell fate commitment; regulation of DNA binding; muscle structure development; multi-organism behavior; R7 cell differentiation. 156 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval digestive system; plasma membrane bounded cell projection; cuboidal/columnar epithelium; stage 7 embryo; chorion; embryonic dorsal vessel; embryonic visceral muscle; single-organism cellular process; egg; tract. The phenotypic classes of alleles include: some die during embryonic stage; behavior defective; cell shape defective; lethal - all die before end of first instar larval stage; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 06-18 hour embryonic stages.  "
FBgn0031913	CG5958	0.305024321	0.36382737	0.999936032	RLBP1	TTPAL;RLBP1	moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5958 (FBgn0031913). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:7430530..7433516. It has the cytological map location 27F4. Protein features are: CRAL-TRIO lipid binding domain; CRAL/TRIO, N-terminal domain; Cellular retinaldehyde binding/alpha-tocopherol transport. Its molecular function is described by: transporter activity. It is involved in the biological process described with: transport. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period.  "
FBgn0261262	CG42613	0.30518095	0.427998632	0.999936032	NA	NRP2;MFRP	low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG42613 (FBgn0261262). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 3R:18929196..18978088. It has the cytological map location 91D5-91E1. Protein features are: CUB domain; Low-density lipoprotein (LDL) receptor class A repeat. Its molecular function is described by: . It is involved in the biological process described with: sleep. 8 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: flight defective; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.  "
FBgn0011648	Mad	0.305222634	0.390026057	0.999936032	NA	SMAD1;SMAD5;SMAD9;SMAD3;SMAD2	high;moderate;moderate;low;low	DNA-binding with transcription factor activity(MH1)	NA	NA	"The gene Mothers against dpp is referred to in FlyBase by the symbol Dmel\Mad (CG12399, FBgn0011648). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:3146056..3159643. It has the cytological map location 23D3. Protein features are: Dwarfin; MAD homology 1, Dwarfin-type; MAD homology, MH1; SMAD domain, Dwarfin-type; SMAD domain-like; SMAD/FHA domain. Its molecular function is described by: RNA polymerase II activating transcription factor binding; RNA polymerase II distal enhancer sequence-specific DNA binding; transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity; RNA polymerase II transcription coactivator activity; transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; DNA binding; sequence-specific DNA binding; protein binding. It is involved in the biological process described with 26 unique terms, many of which group under: gamete generation; regulation of cell cycle process; growth; cell cycle phase transition; stem cell population maintenance; multi-organism process; cellular component assembly; histoblast morphogenesis; animal organ formation; negative regulation of gene expression; germ-line stem cell population maintenance; imaginal disc-derived leg morphogenesis; somatic stem cell population maintenance. 91 alleles are reported. The phenotypes of these alleles manifest in: synapse; hemocyte; sensory system neuron; wing vein L4; membrane-bounded organelle; embryonic/larval dorsal branch; anterior wing margin; embryonic/larval circulatory system; embryonic/larval ventral anastomosis; egg; neuromuscular junction; primary trachea; primordium; fat body; intracellular part; brain. The phenotypic classes of alleles include: some die during P-stage; increased mortality; phenotype; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis.  "
FBgn0263660	CR43651	0.305563652	0.465641546	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR43651 (FBgn0263660). It is a non_protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts. Gene sequence location is 2R:9552844..9553940. It has the cytological map location 45F1. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available.
FBgn0003356	Jon99Cii	0.305852605	0.357550106	0.999936032	NA	C1S;HABP2;PROC	low;low;low	NA	NA	NA	"The gene Jonah 99Cii is referred to in FlyBase by the symbol Dmel\Jon99Cii (CG31034, FBgn0003356). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:29923754..29924615. It has the cytological map location 99C7. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 3 alleles are reported. The phenotypes of these alleles manifest in: male accessory gland secondary cell; vacuole. The phenotypic class of alleles includes: cell shape defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period, in adult male stages.  "
FBgn0085485	CG34456	0.305863497	0.455322635	0.999936032	NA	PDXK	low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG34456 (FBgn0085485). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:9362108..9362734. It has the cytological map location 67B2. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed during late larval stages, in adult male stages.  "
FBgn0266668	Exo84	0.305883371	0.411193817	0.999936032	NA	EXOC8	high	NA	NA	NA	"The gene Exocyst 84 is referred to in FlyBase by the symbol Dmel\Exo84 (CG6095, FBgn0266668). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:26049731..26052257. It has the cytological map location 96F10. Protein features are: Cullin repeat-like-containing domain; Exocyst complex component Exo84; Exocyst component Exo84, C-terminal; PH domain-like; Pleckstrin homology domain. Its molecular function is described by: . It is involved in the biological process described with 16 unique terms, many of which group under: cellular component assembly; maintenance of cell polarity; exocyst localization; cellular macromolecule localization; endosomal transport; cellular protein complex localization; establishment or maintenance of bipolar cell polarity; neuron projection morphogenesis; sexual reproduction; protein complex localization. 9 alleles are reported. The phenotypes of these alleles manifest in: embryonic/first instar larval cuticle; embryo; epidermal cell; mesothoracic tergum; Nebenkern. The phenotypic classes of alleles include: increased mortality; cell cycle defective; phenotype; some die during larval stage; some die during pharate adult stage."
FBgn0003463	sog	0.305911577	0.409169395	0.999936032	NA	CHRD;CHRDL1	high;moderate	NA	transmembrane protein	NA	"The gene short gastrulation is referred to in FlyBase by the symbol Dmel\sog (CG9224, FBgn0003463). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is X:15603283..15633434. It has the cytological map location 13E1-13E3. Protein features are: CHRD; Chordin; VWFC domain. Its molecular function is described by: collagen binding. It is involved in the biological process described with 13 unique terms, many of which group under: embryo development; ring gland development; dorsal/ventral axis specification; oocyte differentiation; ectoderm development; tripartite regional subdivision; morphogenesis of an epithelium; dorsal/ventral pattern formation; positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; torso signaling pathway. 103 alleles are reported. The phenotypes of these alleles manifest in: dorsal closure embryo; chorionic specialization; cell; cell part; embryonic/larval visceral branch; external encapsulating structure; embryonic/larval dorsal branch; neurogenic region; embryonic/first instar larval cuticle; corpus cardiacum primordium; embryonic/larval dorsal trunk. The phenotypic classes of alleles include: lethal - all die before end of embryonic stage; phenotype; increased mortality during development; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0032505	CG16826	0.305941086	0.282815302	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG16826 (FBgn0032505). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:13347773..13349020. It has the cytological map location 34B6. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of no expression detected.  Peak expression observed in adult male stages.
FBgn0040467	Dlip1	0.305958402	0.462079964	0.999936032	NA	NA	NA	DNA-binding with transcription factor activity	NA	NA	"The gene Dorsal interacting protein 1 is referred to in FlyBase by the symbol Dmel\Dlip1 (CG15367, FBgn0040467). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:9158622..9159375. It has the cytological map location 8C14. Protein features are: Zinc finger C2H2-type; Zinc finger, AD-type. Its molecular function is described by: nucleic acid binding; zinc ion binding. It is involved in the biological process described with: lateral inhibition. 3 alleles are reported. The phenotypes of these alleles manifest in: chaeta; mesothoracic tergum. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0040466	Dlip2	0.306016206	0.424333037	0.999936032	NA	NA	NA	Maybe TF(THAP)	NA	NA	"The gene Dorsal interacting protein 2 is referred to in FlyBase by the symbol Dmel\Dlip2 (CG9771, FBgn0040466). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:4644649..4645655. It has the cytological map location 82C5. Protein features are: Zinc finger, C2CH-type. Its molecular function is described by: protein binding; nucleic acid binding. It is involved in the biological process described with: . 8 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval hemocyte. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0002869	MtnB	0.306078934	0.449715995	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Metallothionein B is referred to in FlyBase by the symbol Dmel\MtnB (CG4312, FBgn0002869). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:20503102..20503746. It has the cytological map location 92E12-92E13. Protein features are: Metallothionein, family 5, Diptera. Its molecular function is described by: copper ion binding; metal ion binding. It is involved in the biological process described with: response to metal ion; metal ion homeostasis. 15 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period, at stages throughout the pupal period.  "
FBgn0265464	Traf6	0.306140794	0.39829953	0.999936032	NA	TRAF6	high	NA	NA	NA	"The gene TNF-receptor-associated factor 6 is referred to in FlyBase by the symbol Dmel\Traf6 (CG10961, FBgn0265464). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:8154599..8157386. It has the cytological map location 7D16. Protein features are: MATH/TRAF domain; TNF receptor-associated factor 4; TRAF-like; Zinc finger, RING-type; Zinc finger, RING-type, conserved site; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: ubiquitin-protein transferase activity; protein binding; zinc ion binding. It is involved in the biological process described with 12 unique terms, many of which group under: macromolecule metabolic process; organic substance metabolic process; defense response; autophagy; multi-organism cellular process; anatomical structure morphogenesis; intracellular signal transduction; negative regulation of signaling; embryo development ending in birth or egg hatching; regulation of response to biotic stimulus; immune response; embryo development. 13 alleles are reported. The phenotypes of these alleles manifest in: intestinal stem cell; germline cell; wing. The phenotypic classes of alleles include: visible; viable; immune response defective."
FBgn0033405	CG13954	0.306382961	0.402582528	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13954 (FBgn0033405). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:9309296..9389467. It has the cytological map location 45C5-45D1. Its molecular function is unknown. The biological processes in which it is involved are not known. 12 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages.  "
FBgn0032479	CG16974	0.306420329	0.400986593	0.999936032	NA	IGFALS;VASN	low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG16974 (FBgn0032479). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:13183849..13191979. It has the cytological map location 34A8. Protein features are: Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold; Leucine-rich repeat; Leucine-rich repeat domain, L domain-like; Leucine-rich repeat, typical subtype. Its molecular function is unknown. It is involved in the biological process described with: neuron projection morphogenesis. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0034989	CG3356	0.306471042	0.417359718	0.999936032	UBE3C	UBE3C;UBE3B	high;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3356 (FBgn0034989). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:24197824..24202187. It has the cytological map location 60C2. Protein features are: HECT domain; IQ motif, EF-hand binding site. Its molecular function is described by: ubiquitin protein ligase activity; ubiquitin-protein transferase activity; ubiquitin conjugating enzyme binding. It is involved in the biological process described with: protein polyubiquitination. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0004859	ci	0.306589338	0.459475745	0.999936032	NA	GLI2;GLI3;GLI1	high;high;moderate	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene cubitus interruptus is referred to in FlyBase by the symbol Dmel\ci (CG2125, FBgn0004859). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 4:47710..57041. It has the cytological map location 102A1-102A3. Protein features are: Zinc finger C2H2-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding; RNA polymerase II distal enhancer sequence-specific DNA binding; protein homodimerization activity; transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding; RNA polymerase II regulatory region sequence-specific DNA binding; protein binding; DNA binding; transcription factor activity, sequence-specific DNA binding; transcription regulatory region DNA binding. It is involved in the biological process described with 22 unique terms, many of which group under: sensory organ morphogenesis; positive regulation of G1/S transition of mitotic cell cycle; columnar/cuboidal epithelial cell development; cell projection organization; signaling; organ or tissue specific immune response; genital disc anterior/posterior pattern formation; epidermis development; negative regulation of cellular metabolic process; mucosal immune response; eye development; columnar/cuboidal epithelial cell differentiation; single organism signaling. 186 alleles are reported. The phenotypes of these alleles manifest in: dorsal multidendritic neuron; embryonic/larval thoracic/abdominal dorsal sensory cluster; non-membrane-bounded organelle; embryonic/larval head sensillum; denticle; adult central nervous system; adult abdomen; S phase; anlage; basal stalk; scutellum; dorsal closure embryo; trachea; adult alimentary canal; wing vein L4; keyhole structure. The phenotypic classes of alleles include: cell number defective; cell cycle defective; increased mortality; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0261437	CSN8	0.306626063	0.420196556	0.999936032	NA	COPS8	high	NA	NA	NA	"The gene COP9 signalosome subunit 8 is referred to in FlyBase by the symbol Dmel\CSN8 (CG42522, FBgn0261437). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:8364855..8365663. It has the cytological map location 29A1-29A2. Protein features are: CSN8/PSMD8/EIF3K; Winged helix-turn-helix DNA-binding domain. Its molecular function is described by: NEDD8 activating enzyme activity; NEDD8-specific protease activity. It is involved in the biological process described with 12 unique terms, many of which group under: regulation of cell cycle; response to external biotic stimulus; regulation of primary metabolic process; sexual reproduction; imaginal disc-derived appendage morphogenesis; cellular component biogenesis; cellular protein metabolic process; protein metabolic process; oogenesis; appendage morphogenesis; response to bacterium; cellular response to stress; regulation of metabolic process; regulation of protein stability; embryo development; cellular macromolecular complex assembly. 9 alleles are reported. The phenotypes of these alleles manifest in: ovary; melanotic mass; posterior crossvein; eye; wing; scutellum; wing vein; mesothoracic tergum. The phenotypic classes of alleles include: lethal; phenotype; increased mortality during development; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0036257	RhoGAP68F	0.306714865	0.406634737	0.999936032	ARHGAP1	ARHGAP1;ARHGAP8;PRR5-ARHGAP8	high;moderate;moderate	NA	NA	NA	"The gene Rho GTPase activating protein at 68F is referred to in FlyBase by the symbol Dmel\RhoGAP68F (CG6811, FBgn0036257). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 3L:12138868..12143380. It has the cytological map location 68F5-68F6. Protein features are: CRAL-TRIO lipid binding domain; Rho GTPase activation protein; Rho GTPase-activating protein domain. Its molecular function is described by: GTPase activator activity; Rab GTPase binding. It is involved in the biological process described with: ventral furrow formation; Rho protein signal transduction; negative regulation of stress fiber assembly; negative regulation of endocytic recycling; imaginal disc-derived leg morphogenesis; positive regulation of synaptic growth at neuromuscular junction. 17 alleles are reported. The phenotypes of these alleles manifest in: wing disc; epithelium; embryonic/first instar larval cuticle; ventral furrow; endosome; lateral plasma membrane; intersegmental nerve; leg. The phenotypic classes of alleles include: lethal; viable; neuroanatomy defective; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0003651	svp	0.306756009	0.361531614	0.999936032	NA	NR2F1;NR2F2;NR2F6;RXRA;RXRG;RXRB	high;moderate;moderate;low;low;low	DNA-binding with transcription factor activity(zf-C4)	NA	NA	"The gene seven up is referred to in FlyBase by the symbol Dmel\svp (CG11502, FBgn0003651). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 3R:12258737..12302785. It has the cytological map location 87B4-87B5. Protein features are: Nuclear hormone receptor; Nuclear hormone receptor, ligand-binding domain; Transcription factor COUP; Zinc finger, NHR/GATA-type; Zinc finger, nuclear hormone receptor-type. Its molecular function is described by: protein binding; receptor activity; zinc ion binding; sequence-specific DNA binding; protein heterodimerization activity; steroid hormone receptor activity; transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding; RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding; protein homodimerization activity. It is involved in the biological process described with 17 unique terms, many of which group under: cardioblast differentiation; digestive tract morphogenesis; chemical synaptic transmission; response to external stimulus; response to organic cyclic compound; phototaxis; Malpighian tubule morphogenesis; cellular biosynthetic process; central nervous system development; cellular response to stimulus. 70 alleles are reported. The phenotypes of these alleles manifest in: U neuron; embryonic/larval optic stalk surface glial cell; excretory system; subesophageal ganglion neuron; U1 neuron; 6-4Ii; adult thorax; epithelial cell; mechanosensory system; embryonic/larval optic stalk; early ommatidial precursor cluster; embryonic/larval ostia; adult external thorax. The phenotypic classes of alleles include: some die during embryonic stage; increased mortality; fertile; lethal - all die before end of first instar larval stage; visible; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult male stages.  "
FBgn0041183	Tep1	0.306785784	0.384667714	0.999936032	NA	CD109;C3;C4B;C4A;A2ML1;C5	moderate;low;moderate;low;low;low	NA	NA	NA	"The gene Thioester-containing protein 1 is referred to in FlyBase by the symbol Dmel\Tep1 (CG18096, FBgn0041183). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:15888640..15893811. It has the cytological map location 35D6. Protein features are: Alpha-2-macroglobulin; Alpha-2-macroglobulin, N-terminal; Alpha-2-macroglobulin, N-terminal 2; Alpha-2-macroglobulin, conserved site; Alpha-2-macroglobulin, thiol-ester bond-forming; Alpha-macroglobulin complement component; Alpha-macroglobulin, receptor-binding; Immunoglobulin-like fold; Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid. Its molecular function is described by: endopeptidase inhibitor activity. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0010044	GstD8	0.306915062	0.282846321	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Glutathione S transferase D8 is referred to in FlyBase by the symbol Dmel\GstD8 (CG4421, FBgn0010044). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:12380008..12380815. It has the cytological map location 87B8. Protein features are: Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Thioredoxin-like fold. Its molecular function is described by: glutathione transferase activity; glutathione peroxidase activity. It is involved in the biological process described with: glutathione metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0001234	Hsromega	0.307036177	0.359184363	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Heat shock RNA “Š is referred to in FlyBase by the symbol Dmel\Hsr“Š (CR31400, FBgn0001234). It is a non_protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts. Gene sequence location is 3R:21296127..21317836. It has the cytological map location 93D4-93D5. Its molecular function is unknown. It is involved in the biological process described with: nuclear speck organization; oogenesis; regulation of proteolysis; positive regulation of cellular protein metabolic process; protein localization; positive regulation of apoptotic process; positive regulation of JNK cascade. 29 alleles are reported. The phenotypes of these alleles manifest in: ommatidial precursor cluster; ommatidium; embryonic/larval neuromuscular junction; rhabdomere; eye; NMJ bouton. The phenotypic classes of alleles include: female fertile; male fertile; behavior defective; fertile; visible; increased mortality during development; viable; temperature response defective; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 06-18 hour embryonic stages.  "
FBgn0027342	fz4	0.307223561	0.432175132	0.999936032	NA	FZD4;SFRP2;FZD10;FZD9;SFRP5;SFRP1	high;high;moderate;moderate;moderate;moderate	NA	transmembrane protein	GPCR	"The gene frizzled 4 is referred to in FlyBase by the symbol Dmel\fz4 (CG4626, FBgn0027342). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:7106272..7110321. It has the cytological map location 6F5. Protein features are: Frizzled domain; Frizzled-4; Frizzled/Smoothened, transmembrane domain; Frizzled/secreted frizzled-related protein; GPCR, family 2-like. Its molecular function is described by: Wnt-protein binding; Wnt-activated receptor activity; transmembrane signaling receptor activity; G-protein coupled receptor activity. It is involved in the biological process described with: signal transduction; canonical Wnt signaling pathway; G-protein coupled receptor signaling pathway; non-canonical Wnt signaling pathway. 11 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0035207	Herc4	0.307703968	0.415427625	0.999936032	NA	HERC4;HERC3;HERC5;HERC6;LOC101929134;HECTD2	high;moderate;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene SUMO-related HECT domain and RCC repeat protein for Toll pathway activation is referred to in FlyBase by the symbol Dmel\Sherpa (CG9153, FBgn0035207). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:1313696..1318330. It has the cytological map location 61F6. Protein features are: HECT domain; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; Regulator of chromosome condensation, RCC1. Its molecular function is described by: ubiquitin-protein transferase activity; ubiquitin protein ligase activity. It is involved in the biological process described with: protein autoubiquitination; positive regulation of MyD88-dependent toll-like receptor signaling pathway; positive regulation of protein localization to plasma membrane; protein ubiquitination. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0031275	GABA-B-R3	0.308637069	0.313609231	0.999936032	NA	GABBR2;GABBR1;GPR156	moderate;moderate;high	Maybe TF	transmembrane protein	GPCR	"The gene metabotropic GABA-B receptor subtype 3 is referred to in FlyBase by the symbol Dmel\GABA-B-R3 (CG3022, FBgn0031275). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (4 unique). Gene sequence location is 2L:749945..762399. It has the cytological map location 21E2. Protein features are: GPCR family 3, C-terminal; GPCR family 3, GABA-B receptor; GPCR family 3, gamma-aminobutyric acid receptor, type B1; GPCR, family 3; Periplasmic binding protein-like I; Receptor, ligand binding region. Its molecular function is described by: G-protein coupled GABA receptor activity. It is involved in the biological process described with: G-protein coupled receptor signaling pathway; regulation of glucose metabolic process; sleep. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: sleep defective; circadian rhythm defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, during early larval stages, during late pupal stages.  "
FBgn0050374	CR30374	0.308637069	0.313609231	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR30374 (FBgn0050374). It is a pseudogene_attribute from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2R:8157257..8157914. It has the cytological map location 44B5. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed in adult male stages.
FBgn0243516	Vrp1	0.30864282	0.43306228	0.999936032	NA	WIPF1;WIPF2	high;moderate	NA	NA	NA	"The gene Verprolin 1 is referred to in FlyBase by the symbol Dmel\Vrp1 (CG13503, FBgn0243516). It is a protein_coding_gene from Drosophila melanogaster. It has 12 annotated transcripts and 12 polypeptides (7 unique). Gene sequence location is 2R:22106107..22122562. It has the cytological map location 58B8-58B9. Protein features are: WH2 domain. Its molecular function is described by: actin filament binding. It is involved in the biological process described with: regulation of actin filament polymerization; positive regulation of actin filament polymerization; myoblast fusion; visceral muscle development; spermatid development; behavioral response to ethanol. 28 alleles are reported. The phenotypes of these alleles manifest in: cell part; organ system subdivision; membrane; hypodermal muscle of head; organelle part; intracellular organelle; plasma membrane; actin filament; adult mesothoracic segment; mesothoracic segment. The phenotypic classes of alleles include: phenotype; visible; increased mortality; sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0037722	CG8319	0.309715319	0.459311099	0.999936032	NA	ZNF410;ZNF707;ZNF121;ZNF358;ZNF575;ZNF70;PRDM5;ZNF521;ZSCAN32;ZNF850;ZNF560	low;low;low;low;low;low;low;low;low;low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8319 (FBgn0037722). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:9627321..9628676. It has the cytological map location 85E1. Protein features are: Zinc finger C2H2-type; Zinc finger, AD-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: nucleic acid binding; zinc ion binding. The biological processes in which it is involved are not known. 6 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0037897	CG5270	0.309768216	0.459796905	0.999936032	NA	ZFYVE26	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5270 (FBgn0037897). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:11422092..11429969. It has the cytological map location 86E5. Protein features are: FYVE zinc finger; Zinc finger, FYVE-related; Zinc finger, FYVE/PHD-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: metal ion binding. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed during early pupal stages.  "
FBgn0034664	CG4377	0.309792863	0.35313651	0.999936032	NA	LYNX1;LY6D	low;low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG4377 (FBgn0034664). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:21835448..21836357. It has the cytological map location 58A2. Protein features are: Domain of unknown function DUF753. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed in adult male stages.
FBgn0051072	Lerp	0.309806128	0.359589832	0.999936032	NA	IGF2R	high	NA	transmembrane protein	NA	"The gene lysosomal enzyme receptor protein is referred to in FlyBase by the symbol Dmel\Lerp (CG31072, FBgn0051072). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 3R:26842462..26863130. It has the cytological map location 97D2-97D3. Protein features are: Cation-independent mannose-6-phosphate receptor; Mannose-6-phosphate receptor binding domain. Its molecular function is described by: protein binding; transporter activity. It is involved in the biological process described with: post-Golgi vesicle-mediated transport; lysosomal transport; positive regulation of autophagy. 18 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; chaeta. The phenotypic classes of alleles include: increased mortality; stress response defective; visible; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0045980	niki	0.309876334	0.259715606	0.999936032	NA	NEK8;NEK9	high;moderate	NA	NA	NA	"The gene nimA-like kinase is referred to in FlyBase by the symbol Dmel\niki (CG10951, FBgn0045980). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:24822401..24825648. It has the cytological map location 96A23-96A24. Protein features are: Protein kinase domain; Protein kinase, ATP binding site; Protein kinase-like domain; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; Regulator of chromosome condensation, RCC1; Serine/threonine-protein kinase, active site. Its molecular function is described by: protein serine/threonine kinase activity; ATP binding; signal transducer, downstream of receptor, with serine/threonine kinase activity. It is involved in the biological process described with: protein phosphorylation; neuron projection morphogenesis. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed during late larval stages.  "
FBgn0032169	CG4709	0.310234712	0.455899776	0.999936032	ZGPAT	ZGPAT	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4709 (FBgn0032169). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:9954325..9956176. It has the cytological map location 30F2. Protein features are: G-patch domain; Zinc finger, CCCH-type. Its molecular function is described by: metal ion binding; nucleic acid binding. It is involved in the biological process described with: sleep. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0266916	Cenp-C	0.310338622	0.437228196	0.999936032	NA	KRTCAP2	low	DNA-binding with transcription factor activity(AT_hook)	NA	NA	"The gene Centromeric protein-C is referred to in FlyBase by the symbol Dmel\Cenp-C (CG31258, FBgn0266916). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:8564105..8569248. It has the cytological map location 85A3. Its molecular function is unknown. It is involved in the biological process described with: kinetochore assembly; regulation of stem cell differentiation; female meiosis chromosome segregation; protein localization to kinetochore; mitotic metaphase plate congression; chromosome segregation; protein localization to chromosome, centromeric region; regulation of centromere complex assembly. 46 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval neuroblast; ganglion mother cell; testis; oocyte; wing; male germline stem cell; mitotic prometaphase; eye; chromosome, centromeric region. The phenotypic classes of alleles include: female sterile; lethal - all die before end of second instar larval stage; increased mortality; visible; phenotype; increased mortality during development."
FBgn0261503	CR42651	0.310412444	0.451034089	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CR42651 (FBgn0261503). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3R:6808796..6816379. It has the cytological map location 84A5. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the larval period.  "
FBgn0030706	Lrp4	0.310433937	0.391573015	0.999936032	NA	LRP4	high	DNA-binding with transcription factor activity	transmembrane protein	NA	"The gene LDL receptor related protein 4 is referred to in FlyBase by the symbol Dmel\Lrp4 (CG8909, FBgn0030706). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:15910870..15921013. It has the cytological map location 14A1. Protein features are: EGF-like calcium-binding domain; EGF-like calcium-binding, conserved site; EGF-like domain; EGF-like, conserved site; EGF-type aspartate/asparagine hydroxylation site; Growth factor receptor cysteine-rich domain; LDLR class B repeat; Low-density lipoprotein (LDL) receptor class A repeat; Low-density lipoprotein (LDL) receptor class A, conserved site; Six-bladed beta-propeller, TolB-like. Its molecular function is described by: calcium ion binding. It is involved in the biological process described with: presynaptic active zone organization. 11 alleles are reported. The phenotypes of these alleles manifest in: T-bar; synapse; presynaptic active zone; adult antennal lobe projection neuron; GABAergic neuron; embryonic/larval brain; adult olfactory receptor neuron. The phenotypic classes of alleles include: neuroanatomy defective; small body; lethal; lethal - all die during larval stage; smell perception defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0037853	CG14696	0.310812632	0.444608408	0.999936032	NA	ARRDC1;ARRDC2;ARRDC4;TXNIP;ARRDC3;ARRDC5	moderate;moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14696 (FBgn0037853). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:10882433..10885001. It has the cytological map location 86C7. Protein features are: Arrestin C-terminal-like domain; Arrestin-like, N-terminal; Immunoglobulin E-set. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0052251	Claspin	0.310861029	0.372012181	0.999936032	NA	CLSPN	high	NA	NA	NA	"The gene Claspin is referred to in FlyBase by the symbol Dmel\Claspin (CG32251, FBgn0052251). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:4313483..4318608. It has the cytological map location 64B1. Protein features are: Claspin. Its molecular function is described by: . It is involved in the biological process described with: mitotic DNA replication checkpoint. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal - all die before end of embryonic stage; fertile; chemical sensitive; some die during embryonic stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0003015	osk	0.310976467	0.295483616	0.999936032	NA	NA	NA	NA	NA	NA	"The gene oskar is referred to in FlyBase by the symbol Dmel\osk (CG10901, FBgn0003015). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3R:8935126..8938395. It has the cytological map location 85B7. Protein features are: OSK domain; OST-HTH/LOTUS domain; SGNH hydrolase-type esterase domain. Its molecular function is described by: mRNA binding. It is involved in the biological process described with 19 unique terms, many of which group under: visual behavior; response to light stimulus; positive regulation of nitrogen compound metabolic process; regulation of mRNA stability; anatomical structure morphogenesis; thermosensory behavior; positive regulation of biological process; single-organism behavior; regulation of biological quality; response to radiation; positive regulation of cellular protein metabolic process. 187 alleles are reported. The phenotypes of these alleles manifest in: cytoplasm; cuboidal/columnar epithelium; abdominal segment 1; abdominal segment 3; eo support cell; embryonic thorax; trichome field; egg; eo-type sensillum; abdominal segment 6; cell; embryonic epidermis. The phenotypic classes of alleles include: phenotype; increased mortality; behavior defective; sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0036227	CG17826	0.310976467	0.295483616	0.999936032	NA	MATN2	low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG17826 (FBgn0036227). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:11949839..11952225. It has the cytological map location 68E3. Protein features are: Chitin binding domain. Its molecular function is described by: chitin binding. It is involved in the biological process described with: chitin metabolic process. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period.
FBgn0263996	CG43739	0.310976467	0.295483616	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG43739 (FBgn0263996).The gene has a gene model, but the supporting evidence is inconclusive. It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:20871335..20918931. It has the cytological map location 38F3-38F5. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available."
FBgn0266758	Esyt2	0.311058632	0.458462037	0.999936032	NA	ESYT2;ESYT3;ESYT1	high;high;moderate	NA	transmembrane protein	NA	"The gene Extended synaptotagmin-like protein 2 is referred to in FlyBase by the symbol Dmel\Esyt2 (CG6643, FBgn0266758). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 3R:24544719..24556549. It has the cytological map location 96A7. Protein features are: C2 domain; Synaptotagmin-like mitochondrial-lipid-binding domain. Its molecular function is described by: calcium-dependent phospholipid binding. It is involved in the biological process described with: synaptic vesicle exocytosis; intracellular transport. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable."
FBgn0030263	CG2076	0.311101889	0.358047317	0.999936032	GHITM	GHITM	high	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG2076 (FBgn0030263). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:11090210..11092098. It has the cytological map location 10A4. Protein features are: Bax inhibitor 1-related. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed in adult male stages.
FBgn0031822	Phf5a	0.311126717	0.386768234	0.999936032	NA	PHF5A	high	NA	NA	NA	"The gene PHD finger protein 5a is referred to in FlyBase by the symbol Dmel\Phf5a (CG9548, FBgn0031822). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:6490155..6490843. It has the cytological map location 26D9. Protein features are: PHF5-like. Its molecular function is described by: RNA binding. It is involved in the biological process described with: mRNA splicing, via spliceosome; regulation of glucose metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; increased mortality; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0033855	link	0.311384366	0.235806966	0.999936032	NA	NA	NA	NA	NA	NA	"The gene link is referred to in FlyBase by the symbol Dmel\link (CG13333, FBgn0033855). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:13555949..13557342. It has the cytological map location 50B1. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval neuroblast; ganglion mother cell. The phenotypic classes of alleles include: increased mortality during development; phenotype; lethal; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0033802	CG17724	0.311472071	0.40489707	0.999936032	NA	NA	NA	Maybe TF	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG17724 (FBgn0033802). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (2 unique). Gene sequence location is 2R:13176094..13190086. It has the cytological map location 49F4-49F7. Its molecular function is unknown. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.
FBgn0001259	in	0.311913542	0.277130044	0.999936032	INTU	INTU	high	NA	NA	NA	"The gene inturned is referred to in FlyBase by the symbol Dmel\in (CG16993, FBgn0001259). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:20367198..20370259. It has the cytological map location 77B6. Protein features are: PDZ domain. Its molecular function is unknown. It is involved in the biological process described with: establishment of planar polarity; establishment of imaginal disc-derived wing hair orientation; non-sensory hair organization. 48 alleles are reported. The phenotypes of these alleles manifest in: abdominal sternite bristle; wing hair; bract; wing cell; wing; macrochaeta. The phenotypic classes of alleles include: fertile; lethal; viable; visible; planar polarity defective; wild-type. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 06-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0030707	CG8916	0.311913542	0.277130044	0.999936032	GABRA6	GABRA6;GABRA2;GABRA1;GABRA5;GABRA4;GABRA3;GABRG2;GABRG1;GABRG3;GABRE;GLRB;GABRD;GABRP	high;high;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8916 (FBgn0030707). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:15921955..15924558. It has the cytological map location 14A1. Protein features are: Gamma-aminobutyric acid A receptor/Glycine receptor alpha; Gamma-aminobutyric-acid A receptor, alpha subunit; Neurotransmitter-gated ion-channel; Neurotransmitter-gated ion-channel ligand-binding domain; Neurotransmitter-gated ion-channel transmembrane domain; Neurotransmitter-gated ion-channel, conserved site. Its molecular function is described by: GABA-A receptor activity; extracellular ligand-gated ion channel activity. It is involved in the biological process described with: ion transport. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed during late pupal stages.  "
FBgn0262533	CR43087	0.311913542	0.277130044	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR43087 (FBgn0262533). It is a pseudogene_attribute from Drosophila melanogaster. It has 2 annotated transcripts. Gene sequence location is 3L:17874715..17876573. It has the cytological map location 75A7. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available.
FBgn0264975	Nrg	0.311924787	0.413182818	0.999936032	NA	NRCAM;NFASC;CHL1;L1CAM	high;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene Neuroglian is referred to in FlyBase by the symbol Dmel\Nrg (CG1634, FBgn0264975). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (3 unique). Gene sequence location is X:8517373..8555170. It has the cytological map location 7E10-7F4. Protein features are: Fibronectin type III; Immunoglobulin; Immunoglobulin I-set; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold; Neurofascin/L1/NrCAM, C-terminal domain. Its molecular function is described by: calcium ion binding. It is involved in the biological process described with 22 unique terms, many of which group under: mating behavior; reproduction; single-organism metabolic process; imaginal disc morphogenesis; respiratory system development; regulation of cellular process; axon ensheathment; cell-cell adhesion; response to stress; behavior. 66 alleles are reported. The phenotypes of these alleles manifest in: plasma membrane bounded cell projection; synapse; primordium; cell part; cell junction; embryonic/larval circulatory system; glial cell; presumptive embryonic/larval tracheal system; adult neuromuscular junction; compound cell cluster organ; seminal receptacle; epidermis; synapse part; sensory organ cell; FBbt:00003689; thoracic segment. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; behavior defective; fertile; lethal; phenotype; visible."
FBgn0035271	CG2021	0.312081079	0.419632219	0.999936032	LSM8	LSM8	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG2021 (FBgn0035271). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:1777010..1777411. It has the cytological map location 62B4. Protein features are: LSM domain; LSM domain, eukaryotic/archaea-type; Sm-like protein Lsm8. Its molecular function is described by: RNA binding. It is involved in the biological process described with: mRNA splicing, via spliceosome. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during prepupal stage; some die during second instar larval stage; lethal - all die before end of larval stage; lethal; female sterile; some die during pharate adult stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0039004	Nup133	0.312082498	0.457627738	0.999936032	NUP133	NUP133	high	NA	transmembrane protein	NA	"The gene Nucleoporin 133kD is referred to in FlyBase by the symbol Dmel\Nup133 (CG6958, FBgn0039004). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:22690607..22694772. It has the cytological map location 94C1. Protein features are: Nucleoporin, Nup133/Nup155-like, C-terminal; Nucleoporin, Nup133/Nup155-like, N-terminal; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: nucleocytoplasmic transporter activity; structural constituent of nuclear pore. It is involved in the biological process described with: protein import into nucleus; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery; nuclear pore distribution; mRNA export from nucleus; chromatin organization; RNA export from nucleus; regulation of transcription, DNA-templated. 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0040512	zetaCOP	0.312217347	0.35486443	0.999936032	NA	COPZ1;COPZ2	high;moderate	NA	NA	NA	"The gene Coat Protein (coatomer) ‘_ is referred to in FlyBase by the symbol Dmel\‘_COP (CG3948, FBgn0040512). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3L:16671664..16673555. It has the cytological map location 73B5-73B6. Protein features are: AP complex, mu/sigma subunit; Longin-like domain. Its molecular function is unknown. It is involved in the biological process described with: regulation of lipid storage; phagocytosis; retrograde vesicle-mediated transport, Golgi to ER. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; lethal - all die during P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0014857	His3.3A	0.312555892	0.358718991	0.999936032	NA	H3F3B;H3F3A;HIST1H3F;HIST2H3D;H3F3C;HIST2H3C;HIST1H3C;HIST1H3A;HIST1H3B;HIST1H3H;HIST1H3J;HIST1H3D;HIST1H3E;HIST2H3A;HIST1H3I	high;moderate;low;low;moderate;low;low;low;low;low;low;low;low;low;low	NA	NA	NA	"The gene Histone H3.3A is referred to in FlyBase by the symbol Dmel\His3.3A (CG5825, FBgn0014857). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:5055058..5056149. It has the cytological map location 25C3. Protein features are: Histone H2A/H2B/H3; Histone H3/CENP-A; Histone-fold. Its molecular function is described by: DNA binding; protein heterodimerization activity. It is involved in the biological process described with: male meiotic nuclear division. 22 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; some die during pupal stage; lethal - all die before end of pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, during early pupal stages, in stages of adults of both sexes.  "
FBgn0261792	snRNP-U1-C	0.312650056	0.386763111	0.999936032	NA	SNRPC	high	NA	NA	NA	"The gene small ribonucleoprotein particle U1 subunit C is referred to in FlyBase by the symbol Dmel\snRNP-U1-C (CG5454, FBgn0261792). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:18982964..18983650. It has the cytological map location 91E2. Protein features are: Matrin/U1-C, C2H2-type zinc finger; Matrin/U1-C-like, C2H2-type zinc finger; U1 small nuclear ribonucleoprotein C; U1-C, C2H2-type zinc finger; Zinc finger C2H2-type. Its molecular function is described by: zinc ion binding; pre-mRNA 5'-splice site binding. It is involved in the biological process described with: regulation of alternative mRNA splicing, via spliceosome; spliceosomal snRNP assembly; mRNA 5'-splice site recognition; mRNA splicing, via spliceosome. 7 alleles are reported. The phenotypes of these alleles manifest in: sarcomere; myofibril; Z disc; mesothoracic tergum; embryonic/larval neuroblast; ganglion mother cell. The phenotypic classes of alleles include: sterile; increased mortality; phenotype; increased mortality during development."
FBgn0035132	mthl10	0.312658491	0.414533725	0.999936032	NA	NA	NA	NA	transmembrane protein	GPCR	"The gene methuselah-like 10 is referred to in FlyBase by the symbol Dmel\mthl10 (CG17061, FBgn0035132). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (5 unique). Gene sequence location is 3L:332801..342915. It has the cytological map location 61C1. Protein features are: GPCR, family 2, secretin-like; GPCR, family 2-like; Methuselah ectodomain, domain 2; Methuselah, N-terminal domain. Its molecular function is described by: G-protein coupled receptor activity. It is involved in the biological process described with: response to starvation; G-protein coupled receptor signaling pathway; cell surface receptor signaling pathway; determination of adult lifespan. 8 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during early pupal stages.  "
FBgn0264307	orb2	0.312771454	0.399988342	0.999936032	NA	CPEB2;CPEB4;CPEB3;TEX2	high;moderate;moderate;low	NA	NA	NA	"The gene orb2 is referred to in FlyBase by the symbol Dmel\orb2 (CG43782, FBgn0264307). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (2 unique). Gene sequence location is 3L:8937100..8954463. It has the cytological map location 66E4. Protein features are: Cytoplasmic polyadenylation element-binding protein; Cytoplasmic polyadenylation element-binding protein, ZZ domain; RNA recognition motif domain. Its molecular function is described by: translation factor activity, RNA binding; ribosome binding; RNA binding; mRNA binding; mRNA 3'-UTR binding; translation repressor activity, nucleic acid binding; translation activator activity; protein binding. It is involved in the biological process described with: male meiosis I; sperm axoneme assembly; positive regulation of translation; long-term memory; male courtship behavior; negative regulation of cytoplasmic translation; spermatogenesis; negative regulation of translation; sperm individualization; asymmetric cell division. 53 alleles are reported. The phenotypes of these alleles manifest in: mitotic spindle; spermatid; sperm individualization complex; neuroblast; RP2 motor neuron; spermatid cyst; Nebenkern; axoneme. The phenotypic classes of alleles include: neuroanatomy defective; partially lethal - majority die; increased mortality during development; phenotype; memory defective; male semi-sterile; fertile."
FBgn0036826	arx	0.312990747	0.455968956	0.999936032	NA	GTSF1;GTSF1L	high;moderate	NA	NA	NA	"The gene asterix is referred to in FlyBase by the symbol Dmel\arx (CG3893, FBgn0036826). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:18900595..18901554. It has the cytological map location 75E4. Protein features are: TRM13/UPF0224 family, U11-48K-like CHHC zinc finger domain; Zinc finger C2H2-type. Its molecular function is described by: nucleic acid binding. It is involved in the biological process described with: oogenesis; negative regulation of transcription, DNA-templated; gene silencing by RNA. 8 alleles are reported. The phenotypes of these alleles manifest in: ovary; polar follicle cell; oocyte. The phenotypic classes of alleles include: viable; female sterile; male fertile; female fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0032858	CG10949	0.313105051	0.438723323	0.999936032	NA	NA	NA	DNA-binding with transcription factor activity(AT_hook|MADF)	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG10949 (FBgn0032858). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:20415173..20416918. It has the cytological map location 38C6. Protein features are: MADF domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 8 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0030739	SWIP	0.313187854	0.452936881	0.999936032	NA	WASHC4	high	NA	NA	NA	"The gene Strumpellin and WASH-interacting protein is referred to in FlyBase by the symbol Dmel\SWIP (CG13957, FBgn0030739). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:16313709..16317750. It has the cytological map location 14B9. Protein features are: WASH complex subunit 7; WASH complex subunit 7, C-terminal; WASH complex subunit 7, N-terminal; WASH complex subunit 7, central domain. Its molecular function is unknown. It is involved in the biological process described with: endosome organization; endosomal transport; positive regulation of cell adhesion. 3 alleles are reported. The phenotype of these alleles manifest in: macrophage. The phenotypic classes of alleles include: lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.  "
FBgn0053144	CG33144	0.313207007	0.39381726	0.999936032	NA	RNF144A;RNF144B	high;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG33144 (FBgn0053144). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:10740054..10798709. It has the cytological map location 47B9-47B14. Protein features are: E3 ubiquitin ligase RBR family; IBR domain; Zinc finger, RING-type; Zinc finger, RING-type, conserved site. Its molecular function is described by: ubiquitin protein ligase activity; zinc ion binding; ubiquitin conjugating enzyme binding; ubiquitin-protein transferase activity. It is involved in the biological process described with: positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process. 11 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal; fertile; lethal - all die before end of pupal stage; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed at stages throughout the pupal period.  "
FBgn0261266	zuc	0.314422961	0.331212195	0.999936032	NA	PLD6	high	NA	NA	NA	"The gene zucchini is referred to in FlyBase by the symbol Dmel\zuc (CG12314, FBgn0261266). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:11988735..11989882. It has the cytological map location 33B5. Protein features are: Phospholipase D-like domain. Its molecular function is described by: cardiolipin hydrolase activity; endoribonuclease activity, producing 5'-phosphomonoesters. It is involved in the biological process described with: piRNA metabolic process; gene silencing by RNA; karyosome formation; oogenesis; dorsal appendage formation; RNA phosphodiester bond hydrolysis, endonucleolytic. 20 alleles are reported. The phenotypes of these alleles manifest in: oocyte; egg chamber; mitochondrion; egg; karyosome; dorsal appendage. The phenotypic classes of alleles include: fertile; female sterile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0019650	toy	0.314519464	0.380118572	0.999936032	NA	PAX6;PAX4;PITX1;PAX1;PAX9;DUX4L5;DUX4L7;DUX4L6;PAX7;PAX3	high;low;low;low;low;moderate;moderate;moderate;low;low	DNA-binding with transcription factor activity(Homeobox|PAX)	NA	NA	"The gene twin of eyeless is referred to in FlyBase by the symbol Dmel\toy (CG11186, FBgn0019650). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 4:989725..1007922. It has the cytological map location 102F4-102F5. Protein features are: Homeobox domain; Homeobox domain-like; Homeobox, conserved site; Paired domain; Winged helix-turn-helix DNA-binding domain. Its molecular function is described by: RNA polymerase II regulatory region sequence-specific DNA binding; transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding. It is involved in the biological process described with: mushroom body development; ocellus development; regulation of transcription from RNA polymerase II promoter; brain morphogenesis; compound eye development; positive regulation of gene expression; eye-antennal disc development; positive regulation of transcription from RNA polymerase II promoter. 30 alleles are reported. The phenotypes of these alleles manifest in: compound sense organ; tract; head capsule; embryonic brain; eye; postfrons; presumptive embryonic/larval system; embryonic/larval imaginal precursor; imaginal precursor; eye-antennal disc; adult antennal segment. The phenotypic classes of alleles include: lethal - all die before end of P-stage; increased mortality; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period.  "
FBgn0002569	Mal-A2	0.314687876	0.347081914	0.999936032	NA	SLC3A1;SLC3A2	moderate;low	NA	NA	NA	"The gene Maltase A2 is referred to in FlyBase by the symbol Dmel\Mal-A2 (CG8694, FBgn0002569). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:8453627..8455782. It has the cytological map location 44D1. Protein features are: Glycoside hydrolase superfamily; Glycosyl hydrolase, family 13, catalytic domain. Its molecular function is described by: catalytic activity. It is involved in the biological process described with: carbohydrate metabolic process. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, in stages of adults of both sexes.  "
FBgn0266812	CR45274	0.31488346	0.422279867	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45274 (FBgn0266812). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2R:17584095..17584495. It has the cytological map location 54C10. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0033875	CG6357	0.314976713	0.350887949	0.999936032	NA	CTSL;CTSZ;CTSS;CTSC;CTSK;CTSH;CTSB;CTSV	low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6357 (FBgn0033875). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:13840053..13841743. It has the cytological map location 50C6. Protein features are: Cathepsin propeptide inhibitor domain (I29); Peptidase C1A. Its molecular function is described by: cysteine-type peptidase activity. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during early pupal stages, in adult male stages.  "
FBgn0035025	uri	0.314997493	0.446764109	0.999936032	NA	URI1	high	NA	NA	NA	"The gene unconventional prefoldin RPB5 interactor is referred to in FlyBase by the symbol Dmel\uri (CG11416, FBgn0035025). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:24565554..24568082. It has the cytological map location 60D5. Protein features are: Prefoldin alpha-like. Its molecular function is described by: RNA polymerase II transcription corepressor activity; phosphatase inhibitor activity; chromatin binding. It is involved in the biological process described with: negative regulation of catalytic activity; spermatogenesis; negative regulation of phosphatase activity. 9 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; wing. The phenotypic classes of alleles include: some die during first instar larval stage; viable; visible; lethal - all die before end of first instar larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0259711	CG42365	0.315063774	0.382377058	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG42365 (FBgn0259711). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:21666687..21667594. It has the cytological map location 57F7. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. The phenotype of these alleles manifest in: chaeta. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0266410	CG45050	0.315345417	0.349867425	0.999936032	NA	ZFAND6;ZFAND5	high;moderate	DNA-binding with transcription factor activity	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG45050 (FBgn0266410). It is a protein_coding_gene from Drosophila melanogaster. It has 8 annotated transcripts and 8 polypeptides (2 unique). Gene sequence location is 3R:9340216..9362994. It has the cytological map location 85D11. Protein features are: Zinc finger, A20-type; Zinc finger, AN1-type. Its molecular function is described by: DNA binding; zinc ion binding. It is involved in the biological process described with: . 49 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: lethal."
FBgn0037580	DppIII	0.315430989	0.361861329	0.999936032	DPP3	DPP3	high	NA	NA	NA	"The gene Dipeptidyl aminopeptidase III is referred to in FlyBase by the symbol Dmel\DppIII (CG7415, FBgn0037580). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:8344400..8347465. It has the cytological map location 84F13. Protein features are: Dipeptidyl-peptidase 3. Its molecular function is described by: dipeptidyl-peptidase activity. It is involved in the biological process described with: proteolysis. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, in stages of adults of both sexes.  "
FBgn0026737	CG6171	0.315499784	0.41756236	0.999936032	NA	APLF	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6171 (FBgn0026737). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:15362796..15363857. It has the cytological map location 88F1. Protein features are: Zinc finger, C2H2, APLF-like. Its molecular function is described by: 3'-5' exonuclease activity; endodeoxyribonuclease activity; DNA-(apurinic or apyrimidinic site) lyase activity. It is involved in the biological process described with: double-strand break repair; nucleic acid phosphodiester bond hydrolysis; DNA catabolic process, endonucleolytic; single strand break repair. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0032264	Lip4	0.315669518	0.43150969	0.999936032	LIPM	LIPM;LIPK;LIPF;LIPA;LIPJ;LIPN	high;moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"The gene Lipase 4 is referred to in FlyBase by the symbol Dmel\Lip4 (CG6113, FBgn0032264). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 2L:10527572..10531778. It has the cytological map location 31F5. Protein features are: Alpha/Beta hydrolase fold; Alpha/beta hydrolase fold-1; Lipase, eukaryotic. Its molecular function is described by: hydrolase activity, acting on ester bonds. The biological processes in which it is involved are not known. 9 alleles are reported. The phenotype of these alleles manifest in: ovariole. The phenotypic classes of alleles include: viable; fertile; flightless. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 06-12 and 18-24 hour embryonic stages.  "
FBgn0039508	CG3368	0.315746954	0.401524734	0.999936032	NA	THADA	low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3368 (FBgn0039508). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:27283780..27287448. It has the cytological map location 97F1. Protein features are: Armadillo-type fold; Domain of unknown function DUF2428, death-receptor-like. Its molecular function is described by: . It is involved in the biological process described with: . 4 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval hemocyte. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0030631	CG6227	0.315968655	0.433313713	0.999936032	DDX46	DDX46	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6227 (FBgn0030631). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:15345169..15350021. It has the cytological map location 13B7-13B8. Protein features are: ATP-dependent RNA helicase DEAD-box, conserved site; DEAD/DEAH box helicase domain; Helicase superfamily 1/2, ATP-binding domain; Helicase, C-terminal; P-loop containing nucleoside triphosphate hydrolase; RNA helicase, DEAD-box type, Q motif. Its molecular function is described by: ATP-dependent RNA helicase activity; ATP binding; nucleic acid binding. It is involved in the biological process described with: RNA secondary structure unwinding; regulation of alternative mRNA splicing, via spliceosome; mRNA splicing, via spliceosome. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: phenotype; increased mortality during development; increased mortality; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0036319	Ent3	0.316218942	0.448234748	0.999936032	SLC29A4	SLC29A4	high	NA	transmembrane protein	NA	"The gene Equilibrative nucleoside transporter 3 is referred to in FlyBase by the symbol Dmel\Ent3 (CG11010, FBgn0036319). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:12853646..12857428. It has the cytological map location 69E6. Protein features are: Equilibrative nucleoside transporter; Equilibrative nucleoside transporter 4; Major facilitator superfamily domain. Its molecular function is described by: nucleoside transmembrane transporter activity; monoamine transmembrane transporter activity. It is involved in the biological process described with: nucleoside transport; nucleoside transmembrane transport. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, in adult male stages.  "
FBgn0038853	RhoGAP93B	0.316218942	0.448234748	0.999936032	NA	ARHGAP39	high	NA	NA	NA	"The gene Rho GTPase activating protein at 93B is referred to in FlyBase by the symbol Dmel\RhoGAP93B (CG3421, FBgn0038853). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:21083043..21097827. It has the cytological map location 93B10-93B11. Protein features are: MyTH4 domain; Rho GTPase activation protein; Rho GTPase-activating protein domain; WW domain. Its molecular function is described by: GTPase activator activity. It is involved in the biological process described with: signal transduction; positive regulation of GTPase activity; axon guidance; axon midline choice point recognition. 18 alleles are reported. The phenotypes of these alleles manifest in: medial longitudinal fascicle; commissure; ganglionic branch primordium; ventral midline; longitudinal connective; eye. The phenotypic classes of alleles include: viable; visible; fertile; lethal; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, in adult female stages.  "
FBgn0052850	CG32850	0.316317894	0.366767783	0.999936032	NA	RNF11	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32850 (FBgn0052850). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 4:314923..331387. It has the cytological map location 102B3-102B5. Protein features are: Zinc finger, RING-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: ubiquitin protein ligase activity; zinc ion binding; ubiquitin-protein transferase activity. It is involved in the biological process described with: proteasome-mediated ubiquitin-dependent protein catabolic process; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein autoubiquitination. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period.  "
FBgn0046704	Liprin-alpha	0.31638869	0.411433675	0.999936032	NA	PPFIA2;PPFIA1;PPFIA3;PPFIA4	high;moderate;moderate;moderate	NA	NA	NA	"The gene Liprin-‘± is referred to in FlyBase by the symbol Dmel\Liprin-‘± (CG11199, FBgn0046704). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 2L:6723903..6732766. It has the cytological map location 27A1-27A2. Protein features are: LAR-interacting protein, Liprin; Liprin-alpha; Sterile alpha motif domain; Sterile alpha motif/pointed domain. Its molecular function is described by: protein binding. It is involved in the biological process described with 11 unique terms, many of which group under: regulation of neuron projection development; vesicle-mediated transport in synapse; vesicle localization; R7 cell differentiation; regulation of anatomical structure morphogenesis; axo-dendritic transport; microtubule-based movement; axon extension involved in axon guidance; neuromuscular junction development; axon extension; single-organism intracellular transport. 30 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval neuromuscular junction; photoreceptor cell R4; medulla; NMJ bouton; synaptic vesicle; eye photoreceptor cell; synapse; optic cartridge; photoreceptor cell R7. The phenotypic classes of alleles include: lethal; viable; male sterile; neuroanatomy defective; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period, in adult female stages.  "
FBgn0029508	Tsp42Ea	0.316428728	0.38971546	0.999936032	NA	CD63	moderate	NA	transmembrane protein	NA	"The gene Tetraspanin 42Ea is referred to in FlyBase by the symbol Dmel\Tsp42Ea (CG18817, FBgn0029508). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:6992676..7004259. It has the cytological map location 42E4. Protein features are: Tetraspanin; Tetraspanin, EC2 domain; Tetraspanin/Peripherin. Its molecular function is described by: . It is involved in the biological process described with: cell surface receptor signaling pathway. 13 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages.  "
FBgn0015221	Fer2LCH	0.316664782	0.342674257	0.999936032	NA	FTMT	moderate	NA	NA	NA	"The gene Ferritin 2 light chain homologue is referred to in FlyBase by the symbol Dmel\Fer2LCH (CG1469, FBgn0015221). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (2 unique). Gene sequence location is 3R:30387804..30390584. It has the cytological map location 99F2. Protein features are: Ferritin; Ferritin-like diiron domain; Ferritin-like superfamily; Ferritin-related; Ferritin/DPS protein domain. Its molecular function is described by: ferrous iron binding; iron ion binding; ferric iron binding. It is involved in the biological process described with: intracellular sequestering of iron ion; locomotor rhythm; cellular iron ion homeostasis; detoxification of iron ion; hemolymph coagulation; iron ion import across plasma membrane; chaeta development; response to fungus. 54 alleles are reported. The phenotypes of these alleles manifest in: germ band; embryonic/larval cuticle; embryonic brain; ventral nerve cord; embryonic ganglion mother cell; axon; neuroblast; embryonic/larval central nervous system. The phenotypic classes of alleles include: increased mortality during development; phenotype; lethal; increased mortality; fertile; developmental rate defective; locomotor rhythm defective. Summary of modENCODE Temporal Expression Profile:  Very high expression at all stages of development.  "
FBgn0033029	Not3	0.316789422	0.370843165	0.999936032	NA	CNOT3	high	Co-factor	NA	NA	"The gene CCR4-NOT transcription complex subunit 3 is referred to in FlyBase by the symbol Dmel\Not3 (CG8426, FBgn0033029). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:5656406..5663222. It has the cytological map location 41F6. Protein features are: CCR4-NOT complex, subunit 3/ 5; CCR4-Not complex component, Not N-terminal domain; NOT2/NOT3/NOT5. Its molecular function is described by: poly(A)-specific ribonuclease activity; protein binding. It is involved in the biological process described with: mRNA catabolic process; nuclear-transcribed mRNA poly(A) tail shortening; regulation of transcription, DNA-templated; negative regulation of translation. 10 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval pericardial cell; ganglion mother cell; embryonic/larval neuroblast; adult heart. The phenotypic classes of alleles include: some die during pupal stage; lethal - all die before end of pupal stage; neuroanatomy defective; viable; short lived; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, in adult female stages.  "
FBgn0040349	CG3699	0.316852352	0.34714459	0.999936032	NA	HSD17B14;HSD17B8;CBR4;DECR2;BDH2	high;low;low;moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3699 (FBgn0040349). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:946662..947500. It has the cytological map location 1D2-1D3. Protein features are: NAD(P)-binding domain; Short-chain dehydrogenase/reductase SDR; Short-chain dehydrogenase/reductase, conserved site. Its molecular function is described by: 2,4-dienoyl-CoA reductase (NADPH) activity. It is involved in the biological process described with: fatty acid beta-oxidation. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during early pupal stages, in stages of adults of both sexes.  "
FBgn0004244	Rdl	0.31689335	0.400929565	0.999936032	NA	GLRA4;GLRA3;GLRA2;GLRA1;GABRR2;GABRR1;GABRP;GLRB;GABRB2;GABRQ;GABRD;GABRB3;GABRB1	moderate;moderate;moderate;moderate;moderate;moderate;moderate;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene Resistant to dieldrin is referred to in FlyBase by the symbol Dmel\Rdl (CG10537, FBgn0004244). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (5 unique). Gene sequence location is 3L:9145838..9182149. It has the cytological map location 67A1. Protein features are: Gamma-aminobutyric acid A receptor/Glycine receptor alpha; Gamma-aminobutyric-acid A receptor, beta subunit; Neurotransmitter-gated ion-channel; Neurotransmitter-gated ion-channel ligand-binding domain; Neurotransmitter-gated ion-channel transmembrane domain; Neurotransmitter-gated ion-channel, conserved site. Its molecular function is described by: neurotransmitter receptor activity; GABA-A receptor activity; GABA-gated chloride ion channel activity. It is involved in the biological process described with: response to drug; response to mechanical stimulus; ion transport; negative regulation of synaptic transmission; inter-male aggressive behavior; regulation of circadian sleep/wake cycle; regulation of olfactory learning; sleep. 51 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic intersegmental nerve; prothoracic intersegmental nerve; VUM neuron; intersegmental nerve; U neuron; abdominal intersegmental nerve; RP2 motor neuron; aCC neuron; metathoracic intersegmental nerve. The phenotypic classes of alleles include: behavior defective; some die during immature adult stage; sterile; lethal - all die before end of embryonic stage; phenotype; circadian behavior defective; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during early larval stages.  "
FBgn0039006	Cyp6d4	0.316999844	0.353399803	0.999936032	NA	TBXAS1;CYP3A43;CYP3A4;CYP3A5;CYP3A7-CYP3A51P	moderate;low;low;low;low	NA	transmembrane protein	NA	"The gene Cyp6d4 is referred to in FlyBase by the symbol Dmel\Cyp6d4 (CG12800, FBgn0039006). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:22698319..22700307. It has the cytological map location 94C1. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Its molecular function is described by: oxidoreductase activity; heme binding; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. It is involved in the biological process described with: chaeta development; oxidation-reduction process; wing disc development. 8 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed during late larval stages.  "
FBgn0040333	brv3	0.317076993	0.207988861	0.999936032	NA	PKD1L1	high	NA	transmembrane protein	NA	"The gene brivido-3 is referred to in FlyBase by the symbol Dmel\brv3 (CG13762, FBgn0040333). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:2622069..2624575. It has the cytological map location 3A8. Protein features are: Polycystic kidney disease type 2 protein; Polycystin cation channel, PKD1/PKD2. Its molecular function is described by: calcium ion binding; calcium channel activity. It is involved in the biological process described with: calcium ion transport; detection of mechanical stimulus; response to cold. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: cold stress response defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed at stages throughout the pupal period, in adult male stages.  "
FBgn0266178	pre-mod(mdg4)-B	0.317076993	0.207988861	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\pre-mod(mdg4)-B (CG44884, FBgn0266178). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:21354445..21359768. It has the cytological map location 93D8. Protein features are: Zinc finger, FLYWCH-type. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported."
FBgn0037802	Sirt6	0.317119504	0.445505537	0.999936032	SIRT6	SIRT6	high	Chromatin regulation	NA	NA	"The gene Sirtuin 6 is referred to in FlyBase by the symbol Dmel\Sirt6 (CG6284, FBgn0037802). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:10255349..10261849. It has the cytological map location 86A2-86A3. Protein features are: DHS-like NAD/FAD-binding domain; Sirtuin family; Sirtuin family, catalytic core domain. Its molecular function is described by: histone deacetylase activity; NAD+ binding. It is involved in the biological process described with: positive regulation of chromatin silencing; determination of adult lifespan; histone deacetylation. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: short lived; lethal - all die during P-stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0032208	Ufd4	0.317275487	0.394488443	0.999936032	NA	HECTD1	high	NA	NA	NA	"The gene Ubiquitin fusion-degradation 4-like is referred to in FlyBase by the symbol Dmel\Ufd4 (CG5604, FBgn0032208). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:10281943..10292365. It has the cytological map location 31C4-31C6. Protein features are: Ankyrin repeat; Ankyrin repeat-containing domain; Armadillo-like helical; Armadillo-type fold; Galactose-binding domain-like; HECT domain; Mib-herc2; SUN domain. Its molecular function is described by: ubiquitin-protein transferase activity; metal ion binding; ubiquitin protein ligase activity. It is involved in the biological process described with: protein ubiquitination involved in ubiquitin-dependent protein catabolic process. 8 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0024250	brk	0.317369051	0.416392493	0.999936032	NA	NA	NA	DNA-binding with transcription factor activity(BrkDBD)	NA	NA	"The gene brinker is referred to in FlyBase by the symbol Dmel\brk (CG9653, FBgn0024250). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:7307939..7311132. It has the cytological map location 7B1. Protein features are: Brinker DNA-binding domain; WD40/YVTN repeat-like-containing domain; Winged helix-turn-helix DNA-binding domain. Its molecular function is described by: transcription factor activity, sequence-specific DNA binding; sequence-specific DNA binding; RNA polymerase II distal enhancer sequence-specific DNA binding; enhancer sequence-specific DNA binding. It is involved in the biological process described with 12 unique terms, many of which group under: posterior Malpighian tubule development; animal organ formation; response to BMP; regulation of cellular response to transforming growth factor beta stimulus; negative regulation of transcription, DNA-templated; regionalization; growth; pattern specification process; negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; gland development. 84 alleles are reported. The phenotypes of these alleles manifest in: ventral abdominal cluster; embryonic/larval epidermis; dorsal appendage; chorion; embryonic/larval hemocyte; gland; epithelial furrow; hemocoel; external compound sense organ; embryonic imaginal precursor; ventral nerve cord; hypostomal sclerite; cell; embryonic nervous system of abdomen. The phenotypic classes of alleles include: female fertile; cell number defective; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-18 hour embryonic stages.  "
FBgn0036396	CG17359	0.317483084	0.44060649	0.999936032	NA	KLF8;ZNF281;VEZF1;KLF12;ZNF740;KLF3;MAZ;ZBTB45;ZNF576;ZNF672;ZNF383;ZIK1;ZNF771;ZNF25;ZNF514;ZNF764;ZSCAN31;ZNF501;ZSCAN30;ZNF157;ZFP3;ZNF793;ZNF154;ZNF165;ZSCAN9;ZNF787;ZNF146;ZNF391;ZNF70;ZNF774	low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17359 (FBgn0036396). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:13997900..13999251. It has the cytological map location 70C11. Protein features are: Zinc finger C2H2-type; Zinc finger, AD-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: nucleic acid binding; zinc ion binding. The biological processes in which it is involved are not known. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die during embryonic stage; viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0031505	ND-B14.5B	0.317528931	0.35213344	0.999936032	NA	NDUFC2;NDUFC2-KCTD14	high;moderate	NA	transmembrane protein	NA	"The gene NADH dehydrogenase (ubiquinone) B14.5 B subunit is referred to in FlyBase by the symbol Dmel\ND-B14.5B (CG12400, FBgn0031505). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:3144953..3145848. It has the cytological map location 23D2-23D3. Protein features are: NADH:ubiquinone oxidoreductase, subunit b14.5b. Its molecular function is described by: NADH dehydrogenase (ubiquinone) activity; NADH dehydrogenase activity. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone. 4 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; trichogen cell; adult heart. The phenotypic classes of alleles include: viable; lethal - all die during P-stage; visible; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed within 06-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0266197	CR44892	0.317666594	0.449411632	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44892 (FBgn0266197). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is X:498097..499456. It has the cytological map location 1B6. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available.
FBgn0036652	CG13032	0.317903523	0.315012691	0.999936032	NA	CCDC13	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG13032 (FBgn0036652). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:16673964..16676264. It has the cytological map location 73B6. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed in adult male stages.
FBgn0019972	Drice	0.318113113	0.391072368	0.999936032	NA	CASP7;CASP3;CASP6;CASP9;CFLAR;CASP2;CASP8;CASP10	moderate;moderate;moderate;low;moderate;low;low;low	NA	NA	NA	"The gene Death related ICE-like caspase is referred to in FlyBase by the symbol Dmel\Drice (CG7788, FBgn0019972). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:29799658..29801584. It has the cytological map location 99C1. Protein features are: Caspase-like domain; Peptidase C14,  p20 domain; Peptidase C14, caspase non-catalytic subunit p10; Peptidase C14A, caspase catalytic domain; Peptidase family C14A, His active site; Peptidase family C14A, cysteine active site. Its molecular function is described by: cysteine-type endopeptidase activity involved in execution phase of apoptosis; cysteine-type endopeptidase activity; BIR domain binding; cysteine-type endopeptidase activity involved in apoptotic process. It is involved in the biological process described with 13 unique terms, many of which group under: single organism reproductive process; regulation of signal transduction; salivary gland development; response to abiotic stimulus; positive regulation of cell development; regulation of cysteine-type endopeptidase activity; germ cell development; response to radiation; SREBP signaling pathway; apoptotic process involved in development; salivary gland morphogenesis; response to ionizing radiation. 35 alleles are reported. The phenotypes of these alleles manifest in: cell; prepupa; gland; plasma membrane bounded cell projection; midline glial cell; cell part; neuromere; eye disc; inter-ommatidial precursor cell; larval thorax; terminalia; foregut; glial cell; germline cell. The phenotypic classes of alleles include: increased mortality; phenotype; increased mortality during development; cell death defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0026206	mei-P26	0.318125443	0.377504502	0.999936032	NA	TRIM56	high	Maybe TF	NA	NA	"The gene meiotic P26 is referred to in FlyBase by the symbol Dmel\mei-P26 (CG12218, FBgn0026206). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (2 unique). Gene sequence location is X:9163255..9189309. It has the cytological map location 8C15-8C17. Protein features are: Armadillo-like helical; B-box, C-terminal; B-box-type zinc finger; NHL repeat; NHL repeat, subgroup; Six-bladed beta-propeller, TolB-like; Zinc finger, RING-type; Zinc finger, RING-type, conserved site; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: ubiquitin-protein transferase activity; zinc ion binding. It is involved in the biological process described with: meiotic cell cycle; protein ubiquitination; germ cell development; gamete generation. 31 alleles are reported. The phenotypes of these alleles manifest in: anatomical structure; non-membrane-bounded organelle; female organism; egg; membrane-bounded organelle; spermatozoon; female germline cell; male germline cell; intracellular organelle part; organelle lumen. The phenotypic classes of alleles include: sterile; female sterile; fertile; meiotic cell cycle defective; viable; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0010300	brat	0.318292315	0.42198944	0.999936032	NA	TRIM3;TRIM2	high;moderate	Maybe TF(zf-B_box)	NA	NA	"The gene brain tumor is referred to in FlyBase by the symbol Dmel\brat (CG10719, FBgn0010300). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (2 unique). Gene sequence location is 2L:19133816..19179758. It has the cytological map location 37C1-37C6. Protein features are: B-box-type zinc finger; NHL repeat; NHL repeat, subgroup; Six-bladed beta-propeller, TolB-like. Its molecular function is described by: translation repressor activity; translation regulator activity; zinc ion binding; protein binding. It is involved in the biological process described with 20 unique terms, many of which group under: regulation of biosynthetic process; establishment of organelle localization; single organism reproductive process; negative regulation of cell differentiation; ncRNA transcription; cell morphogenesis involved in neuron differentiation; neuromuscular junction development; regulation of developmental growth; ganglion mother cell fate determination; germ cell development; synaptic vesicle transport; cellular amide metabolic process; asymmetric neuroblast division resulting in ganglion mother cell formation. 119 alleles are reported. The phenotypes of these alleles manifest in: developing material anatomical entity; female germline stem cell; intracellular; external compound sense organ; RP neuron; non-connected developing system; wing blade anterior compartment; mitotic cell cycle; embryonic segment; cell cycle; egg chamber; organelle; epithelium; neuron projection. The phenotypic classes of alleles include: cell number defective; lethal; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0037870	CG18577	0.318546031	0.358584935	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG18577 (FBgn0037870). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:11196092..11197285. It has the cytological map location 86D7. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages.
FBgn0028380	fal	0.318688933	0.39566303	0.999936032	NA	SAMHD1	high	NA	NA	NA	"The gene falten is referred to in FlyBase by the symbol Dmel\fal (CG9670, FBgn0028380). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3L:19294564..19298830. It has the cytological map location 76A5. Protein features are: HD domain; HD/PDEase domain. Its molecular function is described by: dGTPase activity. It is involved in the biological process described with: dGTP catabolic process. 12 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0051683	CG31683	0.318892166	0.365687574	0.999936032	NA	PLA2G15;LCAT	moderate;moderate	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG31683 (FBgn0051683). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:20447734..20449964. It has the cytological map location 38C7. Protein features are: Alpha/Beta hydrolase fold; Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase. Its molecular function is described by: O-acyltransferase activity. It is involved in the biological process described with: lipid metabolic process. 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed during early pupal stages.
FBgn0038815	CG5466	0.318931959	0.344985313	0.999936032	NA	AES	low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5466 (FBgn0038815). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:20617883..20621269. It has the cytological map location 92F3. Protein features are: Genetic suppressor element-like; Protein-tyrosine phosphatase-like. Its molecular function is unknown. The biological processes in which it is involved are not known. 8 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; embryonic/larval neuroblast; mesothoracic tergum. The phenotypic classes of alleles include: increased mortality during development; phenotype; some die during P-stage; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, during early pupal stages.  "
FBgn0266227	CR44922	0.318931959	0.344985313	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44922 (FBgn0266227). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3R:4375084..4377600. It has the cytological map location 82A5. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0031116	CG1695	0.319002341	0.429781336	0.999936032	SGSM1	SGSM1;SGSM2	moderate;high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1695 (FBgn0031116). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:20433950..20445599. It has the cytological map location 19D1. Protein features are: RUN domain; Rab-GTPase-TBC domain. Its molecular function is described by: GTPase activator activity; Rab GTPase binding. It is involved in the biological process described with: activation of GTPase activity; regulation of vesicle fusion; regulation of GTPase activity; intracellular protein transport. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, in adult male stages.  "
FBgn0027492	wdb	0.319099006	0.360038544	0.999936032	NA	PPP2R5E;PPP2R5A;PPP2R5B;PPP2R5C;PPP2R5D	high;moderate;moderate;moderate;low	NA	NA	NA	"The gene widerborst is referred to in FlyBase by the symbol Dmel\wdb (CG5643, FBgn0027492). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (1 unique). Gene sequence location is 3R:27561675..27582241. It has the cytological map location 98A6-98A8. Protein features are: Armadillo-like helical; Armadillo-type fold; Protein phosphatase 2A, regulatory B subunit, B56. Its molecular function is described by: protein phosphatase regulator activity. It is involved in the biological process described with: autophagy; chromosome segregation; spindle assembly; positive regulation of smoothened signaling pathway; determination of adult lifespan; regulation of cell cycle; negative regulation of protein phosphorylation. 50 alleles are reported. The phenotypes of these alleles manifest in: intersegmental nerve; tormogen cell; trichogen cell; wing hair; eye; tarsal segment; eye disc; embryo; wing. The phenotypic classes of alleles include: phenotype; visible; increased mortality; some die during P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0024227	aurB	0.319119753	0.438595658	0.999936032	NA	AURKC;AURKB;AURKA	moderate;moderate;low	NA	NA	NA	"The gene aurora B is referred to in FlyBase by the symbol Dmel\aurB (CG6620, FBgn0024227). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:10856797..10858094. It has the cytological map location 32B2. Protein features are: Aurora kinase; Aurora kinase B; Protein kinase domain; Protein kinase, ATP binding site; Protein kinase-like domain; Serine/threonine-protein kinase, active site. Its molecular function is described by: protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; ATP binding; histone serine kinase activity. It is involved in the biological process described with 15 unique terms, many of which group under: oogenesis; spindle checkpoint; microtubule cytoskeleton organization involved in mitosis; cell separation after cytokinesis; attachment of spindle microtubules to kinetochore; cytoskeleton-dependent cytokinesis; cell development; DNA conformation change; chromosome condensation; reproductive process. 15 alleles are reported. The phenotypes of these alleles manifest in: female reproductive system; fusome; egg chamber; cell; thorax; spectrosome; chromosomal part; integumentary system; eye disc; intracellular membrane-bounded organelle; stem cell. The phenotypic classes of alleles include: neuroanatomy defective; increased mortality during development; viable; phenotype; cell cycle defective; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0259228	C3G	0.319138032	0.39633164	0.999936032	NA	RAPGEF1	high	NA	NA	NA	"The gene C3G guanyl-nucleotide exchange factor is referred to in FlyBase by the symbol Dmel\C3G (CG42328, FBgn0259228). It is a protein_coding_gene from Drosophila melanogaster. It has 10 annotated transcripts and 10 polypeptides (9 unique). Gene sequence location is X:6780790..6803593. It has the cytological map location 6D2. Protein features are: Ras guanine nucleotide exchange factor domain; Ras guanine-nucleotide exchange factor, conserved site; Ras guanine-nucleotide exchange factors catalytic domain; Ras-like guanine nucleotide exchange factor, N-terminal. Its molecular function is described by: Ras guanyl-nucleotide exchange factor activity; Rap guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: sarcomere organization; Ras protein signal transduction; positive regulation of GTPase activity; muscle attachment; somatic muscle development; regulation of GTPase activity. 18 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval muscle system; embryonic/larval somatic muscle; larval thoracic segment; histaminergic neuron; cell projection; larva; embryonic/larval circulatory system; cell part; larval mesothoracic segment; hemocyte; ventral longitudinal muscle; plasma membrane bounded cell projection; pigment cell. The phenotypic classes of alleles include: increased mortality; viable; increased mortality during development; phenotype; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 12-18 embryonic stages, during late pupal stages.  "
FBgn0032877	CG2617	0.319193911	0.444842027	0.999936032	NA	RNF26;MGRN1;RNF157	high;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG2617 (FBgn0032877). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:20682368..20683629. It has the cytological map location 38D5. Protein features are: Zinc finger, RING-type. Its molecular function is described by: zinc ion binding. It is involved in the biological process described with: . 6 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval fat body; lipid particle. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0020372	TM4SF	0.319214342	0.446210991	0.999936032	NA	CD37;TSPAN19;CD82;TSPAN6;TSPAN7	low;low;low;low;low	NA	transmembrane protein	NA	"The gene Transmembrane 4 superfamily is referred to in FlyBase by the symbol Dmel\TM4SF (CG11303, FBgn0020372). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 2R:23878197..23880860. It has the cytological map location 60A7. Protein features are: Tetraspanin; Tetraspanin, EC2 domain; Tetraspanin/Peripherin. Its molecular function is unknown. It is involved in the biological process described with: cell surface receptor signaling pathway. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late pupal stages.  "
FBgn0260767	CG42565	0.319364397	0.373193029	0.999936032	NA	LITAF	moderate	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG42565 (FBgn0260767). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:22657901..22661389. It has the cytological map location 58F4. Protein features are: LPS-induced tumour necrosis factor alpha factor. Its molecular function is described by: . It is involved in the biological process described with: . 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed in adult female stages.
FBgn0024321	NK7.1	0.319471713	0.423471873	0.999936032	NA	HMX3;HMX2;HMX1	moderate;moderate;moderate	DNA-binding with transcription factor activity(Homeobox)	NA	NA	"The gene NK7.1 is referred to in FlyBase by the symbol Dmel\NK7.1 (CG8524, FBgn0024321). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 3R:14329413..14372951. It has the cytological map location 88B4-88B6. Protein features are: Homeobox domain; Homeobox domain, metazoa; Homeobox domain-like; Homeobox, conserved site. Its molecular function is described by: sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated. 18 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: visible; viable; fertile; lethal - all die before end of pupal stage; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 06-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0085284	Blos3	0.319724336	0.438261897	0.999936032	NA	BLOC1S3	low	NA	NA	NA	"The gene Biogenesis of lysosome-related organelles complex 1, subunit 3 is referred to in FlyBase by the symbol Dmel\Blos3 (CG34255, FBgn0085284). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:18870224..18870897. It has the cytological map location 75E2. Protein features are: BLOC-1 complex, subunit 3. Its molecular function is described by: . It is involved in the biological process described with: endosomal transport. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0033607	CG9062	0.319813006	0.395456758	0.999936032	WDR48	WDR48	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9062 (FBgn0033607). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:11280484..11283971. It has the cytological map location 47E5-47E6. Protein features are: G-protein beta WD-40 repeat; Protein of unknown function DUF3337; Six-bladed beta-propeller, TolB-like; WD40 repeat; WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: ubiquitin binding. It is involved in the biological process described with: protein deubiquitination. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal; some die during pupal stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0051151	wge	0.319848429	0.40697523	0.999936032	NA	BAHCC1;TNRC18	high;moderate	NA	NA	NA	"The gene winged eye is referred to in FlyBase by the symbol Dmel\wge (CG31151, FBgn0051151). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 3R:22710883..22721150. It has the cytological map location 94C2-94C3. Protein features are: Bromo adjacent homology (BAH) domain; Protein winged eye. Its molecular function is described by: transcription regulatory region sequence-specific DNA binding; chromatin binding. It is involved in the biological process described with: imaginal disc morphogenesis; cell differentiation; chromatin silencing; heterochromatin assembly. 10 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0264994	CR44145	0.320315473	0.283939771	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44145 (FBgn0264994). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2L:11736402..11737541. It has the cytological map location 33A1. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0051997	CG31997	0.320350116	0.370244285	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG31997 (FBgn0051997). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 4:154654..156060. It has the cytological map location 102A4. Protein features are: Single domain Von Willebrand factor type C domain. Its molecular function is described by: . It is involved in the biological process described with: . 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; locomotor behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late pupal stages.
FBgn0051344	CG31344	0.320528953	0.442587693	0.999936032	NA	POLR2G	low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31344 (FBgn0051344). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:15223378..15225329. It has the cytological map location 88E3. Protein features are: Domain of unknown function DUF2236. Its molecular function is unknown. The biological processes in which it is involved are not known. 10 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum; ganglion mother cell; embryonic/larval neuroblast. The phenotypic classes of alleles include: increased mortality; flight defective; phenotype; viable; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 12-18 embryonic stages, during late pupal stages.  "
FBgn0002733	E(spl)mbeta-HLH	0.320836803	0.436237082	0.999936032	NA	HES6;HES2;HES1;HES4;BHLHE41;BHLHE40	moderate;low;low;low;moderate;moderate	DNA-binding with transcription factor activity(HLH)	NA	NA	"The gene Enhancer of split m‘_, helix-loop-helix is referred to in FlyBase by the symbol Dmel\E(spl)m‘_-HLH (CG14548, FBgn0002733). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:26005046..26006023. It has the cytological map location 96F9. Protein features are: Myc-type, basic helix-loop-helix (bHLH) domain; Orange domain. Its molecular function is described by: transcription factor activity, sequence-specific DNA binding; protein dimerization activity; sequence-specific DNA binding. It is involved in the biological process described with: compound eye development; negative regulation of transcription from RNA polymerase II promoter. 14 alleles are reported. The phenotypes of these alleles manifest in: scutellar bristle; wing; wing vein; macrochaeta; wing margin bristle; microchaeta; anterior crossvein; wing vein L5. The phenotypic classes of alleles include: some die during pupal stage; lethal - all die before end of pupal stage; viable; visible; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 06-18 hour embryonic stages, during early pupal stages.  "
FBgn0031389	CG4259	0.320907193	0.298184532	0.999936032	NA	KLK3;KLK1;KLKB1;F11;KLK2;KLK11	low;low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4259 (FBgn0031389). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:2127309..2129237. It has the cytological map location 22C3. Protein features are: Peptidase S1, PA clan; Serine proteases, trypsin domain. Its molecular function is unknown. It is involved in the biological process described with: proteolysis. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in adult male stages.  "
FBgn0053542	upd3	0.321251233	0.437138223	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene unpaired 3 is referred to in FlyBase by the symbol Dmel\upd3 (CG33542, FBgn0053542). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:18277233..18284596. It has the cytological map location 17A4. Protein features are: Unpaired protein. Its molecular function is described by: cytokine activity. It is involved in the biological process described with 12 unique terms, many of which group under: single organism signaling; anatomical structure homeostasis; regulation of cellular process; cell-cell signaling; antimicrobial humoral response; maintenance of gastrointestinal epithelium; female gamete generation; system development; response to other organism; developmental process. 28 alleles are reported. The phenotypes of these alleles manifest in: adult gut; extended germ band embryo; adult midgut epithelium; germline cyst; presumptive embryonic/larval system; abdominal segment 6; adult metathoracic segment; retina; wing; ovariole; developing embryonic structure; abdominal segment 4; abdominal segment 7; embryonic metathoracic segment. The phenotypic classes of alleles include: male fertile; phenotype; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very low expression to a trough of extremely low expression.  Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0053260	CG33260	0.321282719	0.415578736	0.999936032	NA	TSEN34	high	Maybe TF	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG33260 (FBgn0053260). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:14760520..14761844. It has the cytological map location 70F4. Protein features are: tRNA intron endonuclease, catalytic domain-like; tRNA-splicing endonuclease, SEN34 subunit. Its molecular function is described by: tRNA-intron endonuclease activity. It is involved in the biological process described with: tRNA-type intron splice site recognition and cleavage. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of very low expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0032647	CG15143	0.321382247	0.22595614	0.999936032	NA	MAATS1	moderate	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG15143 (FBgn0032647). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:17520892..17524549. It has the cytological map location 36C10. Protein features are: CFAP91 domain; Cilia- and flagella-associated protein 91. Its molecular function is described by: . It is involved in the biological process described with: . 5 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: body color defective; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed in adult male stages.
FBgn0001316	klar	0.321672118	0.357873481	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene klarsicht is referred to in FlyBase by the symbol Dmel\klar (CG17046, FBgn0001316). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (all unique). Gene sequence location is 3L:434083..540614. It has the cytological map location 61C1-61C3. Protein features are: KASH domain. Its molecular function is described by: kinesin binding; protein binding. It is involved in the biological process described with 17 unique terms, many of which group under: tube morphogenesis; locomotion; organelle organization; flight; negative regulation of oocyte development; lipid transport; larval visceral muscle development; cuticle pigmentation; organelle transport along microtubule; nucleus localization. 88 alleles are reported. The phenotypes of these alleles manifest in: cell component; lipid particle; multi-tissue structure; abdominal tergite 6; cell part; developing material anatomical entity; adult abdominal segment 6; oocyte nucleus; A1-7 dorsal acute muscle 2; rhabdomere. The phenotypic classes of alleles include: locomotor behavior defective; semi-sterile; fertile; increased mortality; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 12-24 hour embryonic stages, during late pupal stages.  "
FBgn0264326	DNApol-epsilon255	0.321946929	0.37554808	0.999936032	NA	POLE	high	NA	NA	NA	"The gene DNA polymerase ‘µ 255kD subunit is referred to in FlyBase by the symbol Dmel\DNApol-‘µ255 (CG6768, FBgn0264326). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:23348128..23355163. It has the cytological map location 94E13. Protein features are: DNA polymerase epsilon catalytic subunit; DNA polymerase epsilon, catalytic subunit A, C-terminal; DNA polymerase, palm domain; DNA-directed DNA polymerase, family B; DNA-directed DNA polymerase, family B, exonuclease domain; DNA-directed DNA polymerase, family B, multifunctional domain; Ribonuclease H-like domain. Its molecular function is described by: DNA binding; nucleotide binding; zinc ion binding; 3'-5'-exodeoxyribonuclease activity; single-stranded DNA 3'-5' exodeoxyribonuclease activity; DNA-directed DNA polymerase activity. It is involved in the biological process described with: leading strand elongation; endomitotic cell cycle; DNA repair; organ growth; DNA-dependent DNA replication; base-excision repair, gap-filling; mitotic cell cycle; cellular response to DNA damage stimulus; nucleotide-excision repair, DNA gap filling; DNA replication proofreading. 11 alleles are reported. The phenotypes of these alleles manifest in: cell; gland; embryo; embryonic/larval digestive system; external sensory organ; embryonic/larval neuroblast; adult nervous system; foregut; head; somatic precursor cell; nervous system; adult peripheral nervous system. The phenotypic classes of alleles include: size defective; partially lethal; DNA repair defective; locomotor behavior defective; viable; increased mortality during development; phenotype; increased mortality."
FBgn0050051	Tmem18	0.322004642	0.374231985	0.999936032	NA	TMEM18	high	NA	transmembrane protein	NA	"The gene Transmembrane protein 18 is referred to in FlyBase by the symbol Dmel\Tmem18 (CG30051, FBgn0050051). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:12436120..12436990. It has the cytological map location 49A6. Protein features are: Transmembrane protein 18. Its molecular function is described by: . It is involved in the biological process described with: . 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; starvation stress response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0000042	Act5C	0.322066555	0.334612972	0.999936032	NA	ACTB;ACTG1;ACTC1;ACTG2;ACTA1;ACTA2;ACTBL2;POTEI;POTEJ;POTEF;ACTRT3;ACTR1B;ACTR1A;POTEE	high;high;moderate;low;moderate;low;moderate;low;moderate;low;low;low;low;low	NA	NA	NA	"The gene Actin 5C is referred to in FlyBase by the symbol Dmel\Act5C (CG4027, FBgn0000042). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is X:5900861..5905399. It has the cytological map location 5C7. Protein features are: Actin family; Actin, conserved site; Actin/actin-like conserved site. Its molecular function is described by: structural constituent of cytoskeleton. It is involved in the biological process described with: maintenance of protein location in cell; phagocytosis; inter-male aggressive behavior; mushroom body development; sperm individualization; tube formation; chromatin remodeling; mitotic cytokinesis; cytoskeleton organization. 66 alleles are reported. The phenotypes of these alleles manifest in: germline cyst; female organism; Z disc; eye; eo support cell; adult head sensillum; adult cerebral ganglion; arista; adult sensillum; wing; ovariole; mechanosensory chaeta. The phenotypic classes of alleles include: some die during larval stage; fertile; lethal - all die before end of larval stage; increased mortality; phenotype; viable; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.  "
FBgn0261881	l(2)35Be	0.322211266	0.377398329	0.999936032	NA	ANKRD49	high	NA	NA	NA	"The gene lethal (2) 35Be is referred to in FlyBase by the symbol Dmel\l(2)35Be (CG4140, FBgn0261881). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:15006583..15007431. It has the cytological map location 35B8. Protein features are: Ankyrin repeat; Ankyrin repeat-containing domain. Its molecular function is described by: . It is involved in the biological process described with: . 13 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: visible; viable; lethal."
FBgn0261844	pre-mod(mdg4)-V	0.322336295	0.442915772	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\pre-mod(mdg4)-V (CG42776, FBgn0261844). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:21365609..21370249. It has the cytological map location 93D8-93D9. Protein features are: Zinc finger, FLYWCH-type. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  No temporal expression data available due to processing error.  This will be corrected the next time these data and summaries are processed."
FBgn0039338	XNP	0.322353844	0.414899313	0.999936032	NA	ATRX;RAD54L2	high;low	DNA-binding with transcription factor activity	NA	NA	"The gene XNP is referred to in FlyBase by the symbol Dmel\XNP (CG4548, FBgn0039338). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3R:25477868..25482834. It has the cytological map location 96E1-96E2. Protein features are: Helicase superfamily 1/2, ATP-binding domain; Helicase, C-terminal; P-loop containing nucleoside triphosphate hydrolase; SNF2-related, N-terminal domain. Its molecular function is described by: ATP binding; ATPase activity. It is involved in the biological process described with: intrinsic apoptotic signaling pathway; axon guidance; regulation of JNK cascade; glial cell migration; nervous system development; chromosome organization; heterochromatin organization involved in chromatin silencing; DNA replication-independent nucleosome assembly. 24 alleles are reported. The phenotypes of these alleles manifest in: Kenyon cell; scutellum; embryonic/larval glial cell; anterior commissure; interface glial cell; microchaeta; longitudinal connective; posterior commissure; adult mushroom body; adult thorax. The phenotypic classes of alleles include: phenotype; increased mortality during development; visible; fertile; increased mortality; suppressor of variegation. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0030799	CG4872	0.322399997	0.368240644	0.999936032	CRYM	CRYM	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4872 (FBgn0030799). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:16881347..16882790. It has the cytological map location 15B4. Protein features are: NAD(P)-binding domain; Ornithine cyclodeaminase, N-terminal; Ornithine cyclodeaminase/mu-crystallin. Its molecular function is described by: hormone binding; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor; transcription corepressor activity. It is involved in the biological process described with: negative regulation of transcription from RNA polymerase II promoter. 5 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0250830	CG12547	0.322429997	0.377694422	0.999936032	NA	NHLRC2	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12547 (FBgn0250830). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2R:4785855..4788965. It has the cytological map location 41C2. Protein features are: NHL repeat; NHL repeat, subgroup; Six-bladed beta-propeller, TolB-like; Thioredoxin-like fold. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0036255	Atg12	0.322461478	0.416184939	0.999936032	ATG12	ATG12	high	NA	NA	NA	"The gene Autophagy-related 12 is referred to in FlyBase by the symbol Dmel\Atg12 (CG10861, FBgn0036255). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:12136967..12137559. It has the cytological map location 68F5. Protein features are: Ubiquitin-like protein Atg12; Ubiquitin-related domain. Its molecular function is described by: protein tag; Atg8 ligase activity. It is involved in the biological process described with 11 unique terms, many of which group under: catabolic process; anatomical structure regression; organelle disassembly; cellular protein modification process; glucan metabolic process; cellular response to stimulus; exocrine system development; energy reserve metabolic process; mitochondrion disassembly; cellular response to starvation; organic substance catabolic process; organelle assembly; anatomical structure morphogenesis. 5 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval fat body; enterocyte; autophagosome; embryonic/larval salivary gland; intestinal stem cell; gastric caecum; fat body; mitochondrion; embryonic/larval midgut. The phenotypic classes of alleles include: stress response defective; viable; phenotype; increased cell death; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0034645	ND-B12	0.322493655	0.337433721	0.999936032	NA	NDUFB3	high	NA	transmembrane protein	NA	"The gene NADH dehydrogenase (ubiquinone) B12 subunit is referred to in FlyBase by the symbol Dmel\ND-B12 (CG10320, FBgn0034645). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is 2R:21658078..21658777. It has the cytological map location 57F6. Protein features are: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3. Its molecular function is described by: NADH dehydrogenase activity. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal - all die during P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed within 06-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0004860	ph-d	0.32250764	0.406297198	0.999936032	NA	PHC3;PHC2;PHC1;SFMBT2;SCML1	moderate;high;low;moderate;moderate	Chromatin regulation	NA	NA	"The gene polyhomeotic distal is referred to in FlyBase by the symbol Dmel\ph-d (CG3895, FBgn0004860). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:2115727..2123286. It has the cytological map location 2D2. Protein features are: Calponin homology domain; Sterile alpha motif domain; Sterile alpha motif/pointed domain; WD40/YVTN repeat-like-containing domain; Zinc finger, FCS-type. Its molecular function is described by: chaperone binding; core promoter binding; zinc ion binding; chromatin binding. It is involved in the biological process described with: syncytial blastoderm mitotic cell cycle; chromatin silencing; negative regulation of transcription, DNA-templated. 57 alleles are reported. The phenotypes of these alleles manifest in: larva; genitalia; adult head; epidermis; membrane-enclosed lumen; mesothoracic leg anterior compartment; adult abdominal segment 1; metatarsus of male prothoracic leg; wing sensillum; compound sense organ; epithelium; embryonic/larval integumentary system; anatomical cluster; intracellular organelle. The phenotypic classes of alleles include: lethal; increased mortality during development; phenotype; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0029824	CG3726	0.32261379	0.423151651	0.999936032	NA	ZBTB9	low	DNA-binding with transcription factor activity(AT_hook|HTH_psq_like)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3726 (FBgn0029824). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:5917097..5941852. It has the cytological map location 5C7-5C10. Protein features are: BTB/POZ domain; DNA binding HTH domain, Psq-type; Homeobox domain-like; SKP1/BTB/POZ domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: DNA binding. It is involved in the biological process described with: regulation of transcription from RNA polymerase II promoter. 9 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: body color defective; fertile; lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, during early pupal stages.  "
FBgn0040080	pins	0.322710469	0.382943377	0.999936032	NA	GPSM2;GPSM1	high;moderate	NA	NA	NA	"The gene partner of inscuteable is referred to in FlyBase by the symbol Dmel\pins (CG5692, FBgn0040080). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:27582840..27586376. It has the cytological map location 98A8. Protein features are: G-protein-signalling modulator 1; GoLoco motif; Tetratricopeptide repeat; Tetratricopeptide repeat-containing domain; Tetratricopeptide-like helical domain. Its molecular function is described by: GDP-dissociation inhibitor activity; protein domain specific binding; protein binding. It is involved in the biological process described with 12 unique terms, many of which group under: asymmetric cell division; asymmetric protein localization; mitotic cell cycle process; macromolecule localization; basal protein localization; signaling; maintenance of location; cell division; single organism signaling; establishment of localization. 48 alleles are reported. The phenotypes of these alleles manifest in: neuroblast; developing material anatomical entity; anatomical group; peripheral nervous system; multi-cell-component structure; appendage; developing embryonic structure; sensory system; sensory mother cell; supramolecular complex; segment. The phenotypic classes of alleles include: increased mortality during development; phenotype; mitotic cell cycle defective; cell cycle defective; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0037934	CG6830	0.3227369	0.339640676	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6830 (FBgn0037934). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:11680972..11684342. It has the cytological map location 86E15. Protein features are: CHK kinase-like; Protein kinase-like domain; Protein of unknown function DUF227. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during late larval stages.  "
FBgn0036731	CG6333	0.322838461	0.33056848	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6333 (FBgn0036731). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:17480129..17486230. It has the cytological map location 74C4-74D1. Its molecular function is described by: . It is involved in the biological process described with: . 9 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0039994	conu	0.322961278	0.377448767	0.999936032	NA	ARHGAP18;ARHGAP40;ARHGAP28	high;moderate;moderate	NA	NA	NA	"The gene conundrum is referred to in FlyBase by the symbol Dmel\conu (CG17082, FBgn0039994). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is 2R:4744348..4758048. It has the cytological map location 41C1. Protein features are: Rho GTPase activation protein; Rho GTPase-activating protein domain. Its molecular function is described by: protein binding; GTPase activator activity. It is involved in the biological process described with: signal transduction; negative regulation of GTPase activity; positive regulation of GTPase activity; positive regulation of cell proliferation. 12 alleles are reported. The phenotypes of these alleles manifest in: eye; wing disc. The phenotypic classes of alleles include: viable; increased cell size; fertile; cell shape defective; neoplasia. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0039696	Rnb	0.322989117	0.432293454	0.999936032	NA	ARMC5	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG7837 (FBgn0039696). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:29795697..29799354. It has the cytological map location 99C1. Protein features are: Armadillo; Armadillo-like helical; Armadillo-type fold; BTB/POZ domain; SKP1/BTB/POZ domain. Its molecular function is unknown. It is involved in the biological process described with: regulation of circadian rhythm. 7 alleles are reported. The phenotypes of these alleles manifest in: s-LNv neuron; dendritic tree. The phenotypic classes of alleles include: cell size defective; fertile; circadian rhythm defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0040736	IM3	0.323033533	0.28093941	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Immune induced molecule 3 is referred to in FlyBase by the symbol Dmel\IM3 (CG16844, FBgn0040736). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:18387895..18388734. It has the cytological map location 55C4. Protein features are: Immune-induced protein Dim. Its molecular function is described by: . It is involved in the biological process described with: response to bacterium; Toll signaling pathway; antibacterial humoral response. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0050441	CG30441	0.323033533	0.28093941	0.999936032	IFT20	IFT20	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG30441 (FBgn0050441). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:5351717..5352122. It has the cytological map location 41E5. Protein features are: Intraflagellar transport protein 20. Its molecular function is described by: . It is involved in the biological process described with: intraciliary transport; centrosome localization; cilium assembly; protein localization to cilium. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed within 06-12 hour embryonic stages.
FBgn0029134	Prosbeta5	0.323045924	0.336289316	0.999936032	NA	PSMB5;PSMB8;PSMB11	high;moderate;moderate	NA	NA	NA	"The gene Proteasome ‘_5 subunit is referred to in FlyBase by the symbol Dmel\Pros‘_5 (CG12323, FBgn0029134). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:10819978..10821178. It has the cytological map location 47C1. Protein features are: Nucleophile aminohydrolases, N-terminal; Peptidase T1A, proteasome beta-subunit; Proteasome B-type subunit; Proteasome beta-type subunit, conserved site; Proteasome, subunit alpha/beta. Its molecular function is described by: threonine-type endopeptidase activity; endopeptidase activity. It is involved in the biological process described with: proteasome-mediated ubiquitin-dependent protein catabolic process; centrosome cycle. 10 alleles are reported. The phenotypes of these alleles manifest in: actin cytoskeleton; embryonic/larval neuroblast; ganglion mother cell; nurse cell ring canal; egg chamber. The phenotypic classes of alleles include: neuroanatomy defective; lethal - all die during P-stage; viable; lethal; short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-12 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.  "
FBgn0053306	CG33306	0.323345076	0.333400217	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG33306 (FBgn0053306). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:13842888..13843742. It has the cytological map location 34D7. Protein features are: Haemolymph juvenile hormone binding. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during late larval stages.
FBgn0036738	CG7542	0.323393055	0.332974642	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7542 (FBgn0036738). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:17549826..17550980. It has the cytological map location 74D4. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed in adult male stages.  "
FBgn0027654	jdp	0.323566312	0.42846216	0.999936032	DNAJC12	DNAJC12	high	NA	NA	NA	"The gene jdp is referred to in FlyBase by the symbol Dmel\jdp (CG2239, FBgn0027654). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3R:30517059..30527037. It has the cytological map location 99F7. Protein features are: DnaJ domain. Its molecular function is described by: unfolded protein binding. It is involved in the biological process described with: protein folding. 12 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.  "
FBgn0040373	CG3038	0.323566312	0.42846216	0.999936032	NA	B3GALT4;B3GNT9;B3GNT7;B3GNT2;B3GNT8;B3GNT4;B3GNT6;B3GNT3;B3GALNT1	high;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3038 (FBgn0040373). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is X:243954..245856. It has the cytological map location 1A1. Protein features are: Glycosyl transferase, family 31. Its molecular function is described by: galactosyltransferase activity; transferase activity, transferring glycosyl groups. It is involved in the biological process described with: protein glycosylation. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-18 hour embryonic stages.  "
FBgn0266362	CR45010	0.323633564	0.350758778	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45010 (FBgn0266362). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is X:23010972..23011293. It has the cytological map location 20F3. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0264895	RapGAP1	0.323720068	0.405428595	0.999936032	NA	RAP1GAP2;RAP1GAP;SIPA1L3	high;moderate;moderate	NA	NA	NA	"The gene Rap GTPase activating protein 1 is referred to in FlyBase by the symbol Dmel\RapGAP1 (CG44086, FBgn0264895). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 2L:7497805..7578980. It has the cytological map location 28B1-28B2. Protein features are: Galactose-binding domain-like; GoLoco motif; Rap GTPase activating protein domain. Its molecular function is described by: GTPase activator activity. It is involved in the biological process described with: inter-male aggressive behavior; negative regulation of small GTPase mediated signal transduction. 49 alleles are reported. The phenotypes of these alleles manifest in: pigment cell; mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: viable; visible; fertile; lethal; behavior defective."
FBgn0086677	jeb	0.323754225	0.39506239	0.999936032	NA	NA	NA	NA	NA	NA	"The gene jelly belly is referred to in FlyBase by the symbol Dmel\jeb (CG30040, FBgn0086677). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:12085194..12119340. It has the cytological map location 48E1-48E2. Protein features are: Low-density lipoprotein (LDL) receptor class A repeat; Low-density lipoprotein (LDL) receptor class A, conserved site. Its molecular function is described by: transmembrane receptor protein tyrosine kinase activator activity. It is involved in the biological process described with: negative regulation of neuromuscular synaptic transmission; positive regulation of MAPK cascade; visceral muscle development; muscle cell fate specification; compound eye photoreceptor development; mesoderm migration involved in gastrulation; salivary gland morphogenesis; synaptic growth at neuromuscular junction; axon guidance. 17 alleles are reported. The phenotypes of these alleles manifest in: synapse; developing embryonic structure; germ layer; larva; extended germ band embryo; muscle system; neuron projection; endoderm; neuromuscular junction; brain; developing material anatomical entity; embryonic/larval peripheral nervous system. The phenotypic classes of alleles include: phenotype; visible; increased mortality; circadian rhythm defective; lethal - all die before end of second instar larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0267652	pre-mod(mdg4)-N	0.32375465	0.416305014	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\pre-mod(mdg4)-N (CG45990, FBgn0267652). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:21370918..21373575. It has the cytological map location 93D9. Protein features are: Zinc finger, FLYWCH-type. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported."
FBgn0263995	cpo	0.323826798	0.403369617	0.999936032	NA	RBPMS;RBPMS2	high;moderate	NA	NA	NA	"The gene couch potato is referred to in FlyBase by the symbol Dmel\cpo (CG43738, FBgn0263995). It is a protein_coding_gene from Drosophila melanogaster. It has 12 annotated transcripts and 12 polypeptides (7 unique). Gene sequence location is 3R:17919832..18018892. It has the cytological map location 90D1-90E1. Protein features are: Protein couch potato, RNA recognition motif; RNA recognition motif domain. Its molecular function is described by: nucleic acid binding; mRNA binding. It is involved in the biological process described with: olfactory behavior; regulation of hemocyte proliferation; detection of temperature stimulus involved in sensory perception of pain; dormancy process; chemical synaptic transmission. 107 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; phenotype; increased mortality during development; lethal - all die before end of pupal stage."
FBgn0004380	Klp64D	0.323878109	0.396143729	0.999936032	KIF3A	KIF3A;KIF3C;KIF3B	high;moderate;low	NA	NA	NA	"The gene Kinesin-like protein at 64D is referred to in FlyBase by the symbol Dmel\Klp64D (CG10642, FBgn0004380). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:5356864..5359392. It has the cytological map location 64C13. Protein features are: Kinesin motor domain; Kinesin motor domain, conserved site; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: microtubule motor activity; microtubule binding; ATP binding; ATPase activity. It is involved in the biological process described with: microtubule-based movement; neuron projection morphogenesis; sensory perception of sound; positive regulation of Wnt signaling pathway; anterograde axonal transport; axon guidance; non-motile cilium assembly; sensory perception of smell; establishment or maintenance of microtubule cytoskeleton polarity. 25 alleles are reported. The phenotypes of these alleles manifest in: wing margin bristle; sensillum basiconicum of antennal segment 3; cilium; axon; wing margin; wing; sensillum trichodeum of antennal segment 3; denticle. The phenotypic classes of alleles include: increased mortality; visible; phenotype; hypoactive; uncoordinated. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period.  "
FBgn0040725	CG13946	0.324351843	0.201826603	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG13946 (FBgn0040725). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:776536..776941. It has the cytological map location 21E2. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; chaeta; mesothoracic tergum. The phenotypic classes of alleles include: some die during pupal stage; partially lethal - majority die; visible; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed in adult male stages.
FBgn0013681	mt:ND3	0.324731032	0.341977511	0.999936032	NA	ND3	high	NA	transmembrane protein	NA	"The gene mitochondrial NADH-ubiquinone oxidoreductase chain 3 is referred to in FlyBase by the symbol Dmel\mt:ND3 (CG34076, FBgn0013681). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is mitochondrion_genome:5608..5961. Protein features are: NADH:ubiquinone/plastoquinone oxidoreductase, chain 3. Its molecular function is described by: NADH dehydrogenase (ubiquinone) activity. It is involved in the biological process described with: oxidation-reduction process. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, during early larval stages, during early pupal stages.  "
FBgn0086778	nAChRalpha7	0.325060918	0.407961718	0.999936032	NA	CHRFAM7A;CHRNA7	high;moderate	NA	transmembrane protein	NA	"The gene nicotinic Acetylcholine Receptor ‘±7 is referred to in FlyBase by the symbol Dmel\nAChR‘±7 (CG32538, FBgn0086778). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is X:19327075..19348447. It has the cytological map location 18C2-18C3. Protein features are: Neurotransmitter-gated ion-channel; Neurotransmitter-gated ion-channel ligand-binding domain; Neurotransmitter-gated ion-channel transmembrane domain; Neurotransmitter-gated ion-channel, conserved site; Nicotinic acetylcholine receptor. Its molecular function is described by: acetylcholine-gated cation-selective channel activity. It is involved in the biological process described with: synaptic transmission, cholinergic; jump response; visual behavior; chemical synaptic transmission; cation transport; excitatory postsynaptic potential. 35 alleles are reported. The phenotypes of these alleles manifest in: giant fiber neuron; dorsal medial muscle; dendrite; indirect flight muscle motor neuron MN5. The phenotypic classes of alleles include: viable; phenotype; fertile; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages.  "
FBgn0028683	spt4	0.325160816	0.407308307	0.999936032	NA	SUPT4H1	high	Chromatin regulation	NA	NA	"The gene spt4 is referred to in FlyBase by the symbol Dmel\spt4 (CG12372, FBgn0028683). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:12633589..12634172. It has the cytological map location 49B10. Protein features are: RNA polymerase subunit RPABC4/transcription elongation factor Spt4; Spt4/RpoE2 zinc finger; Transcription initiation Spt4; Zinc finger, NHR/GATA-type. Its molecular function is described by: zinc ion binding; single-stranded RNA binding; transcription factor activity, sequence-specific DNA binding; RNA polymerase II core binding; protein heterodimerization activity. It is involved in the biological process described with: chromatin organization; regulation of transcription elongation from RNA polymerase II promoter; negative regulation of DNA-templated transcription, elongation; positive regulation of DNA-templated transcription, elongation; mRNA processing; negative regulation of transcription from RNA polymerase II promoter; transcription elongation from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter. 7 alleles are reported. The phenotypes of these alleles manifest in: fat body; melanotic mass. The phenotypic classes of alleles include: lethal; partially lethal - majority die; melanotic mass phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0039489	CG5880	0.325388077	0.406170271	0.999936032	ZDHHC16	ZDHHC16	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5880 (FBgn0039489). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:27116745..27118532. It has the cytological map location 97E2. Protein features are: Palmitoyltransferase, DHHC domain. Its molecular function is described by: protein-cysteine S-palmitoyltransferase activity. It is involved in the biological process described with: protein palmitoylation. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0037624	CG8223	0.325955821	0.376460301	0.999936032	NA	NASP	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8223 (FBgn0037624). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:8747798..8754104. It has the cytological map location 85A10. Protein features are: Tetratricopeptide repeat; Tetratricopeptide-like helical domain. Its molecular function is described by: . The biological processes in which it is involved are not known. 6 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0033458	CG18446	0.326075353	0.364272667	0.999936032	NA	ZBTB24	low	DNA-binding with transcription factor activity	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG18446 (FBgn0033458). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:9871470..9873646. It has the cytological map location 46C1. Protein features are: Zinc finger C2H2-type. Its molecular function is described by: nucleic acid binding. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 00-12 hour embryonic stages.
FBgn0267736	CR46067	0.326094018	0.416663703	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR46067 (FBgn0267736). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3L:14053100..14054304. It has the cytological map location 70D1. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0010395	Itgbn	0.326282758	0.360368815	0.999936032	NA	ITGB1;ITGB2;ITGB7;ITGB4;ITGB8;ITGB3;ITGB5;ITGB6;ITGBL1	moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene Integrin betanu subunit is referred to in FlyBase by the symbol Dmel\Itgbn (CG1762, FBgn0010395). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:21053033..21058044. It has the cytological map location 39A1. Protein features are: EGF-like domain, extracellular; Integrin beta N-terminal; Integrin beta subunit; Integrin beta subunit, VWA domain; Integrin beta subunit, cytoplasmic domain; Integrin domain; von Willebrand factor, type A. Its molecular function is described by: receptor activity; protein heterodimerization activity; cell adhesion molecule binding. It is involved in the biological process described with: heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; cell adhesion mediated by integrin; melanotic encapsulation of foreign target; apoptotic cell clearance; phagocytosis; muscle cell cellular homeostasis; cell-matrix adhesion; olfactory behavior; negative regulation of synaptic growth at neuromuscular junction. 17 alleles are reported. The phenotypes of these alleles manifest in: intersegmental nerve; NMJ bouton; trichogen cell; embryonic hemocyte; embryonic/larval hemocyte; neuromuscular junction. The phenotypic classes of alleles include: immune response defective; neuroanatomy defective; viable; phenotype; visible; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages.  "
FBgn0037443	Dmtn	0.326761639	0.381380754	0.999936032	NA	TMCC2;TMCC1;TMCC3;TEX28	high;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene Dementin is referred to in FlyBase by the symbol Dmel\Dmtn (CG1021, FBgn0037443). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is 3R:6389162..6405895. It has the cytological map location 83E5-83E6. Protein features are: Testis-specific protein TEX28/transmembrane and coiled-coil domains protein. Its molecular function is described by: . It is involved in the biological process described with: brain development. 15 alleles are reported. The phenotypes of these alleles manifest in: medulla anlage; optic lobe; wing; medulla. The phenotypic classes of alleles include: short lived; viable; majority die during pupal stage; visible; partially lethal - majority die; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed during early pupal stages.  "
FBgn0263659	CR43650	0.326992319	0.424863227	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR43650 (FBgn0263659). It is a non_protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts. Gene sequence location is 2R:16829095..16839494. It has the cytological map location 53D11-53D12. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available.
FBgn0265194	Trpm	0.327140689	0.412726736	0.999936032	NA	TRPM3;TRPM7;TRPM1;TRPM6;TRPM4;TRPM2;TRPM5;TRPM8	high;moderate;moderate;moderate;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene Transient receptor potential cation channel, subfamily M is referred to in FlyBase by the symbol Dmel\Trpm (CG44240, FBgn0265194). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (all unique). Gene sequence location is 2R:15262808..15309368. It has the cytological map location 51E11-51F4. Protein features are: Ankyrin repeat-containing domain; Ion transport domain; TRPM, tetramerisation domain. Its molecular function is described by: cation channel activity; metal ion transmembrane transporter activity; intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity. It is involved in the biological process described with: zinc ion homeostasis; divalent metal ion transport; protein tetramerization; mitochondrion organization; magnesium ion homeostasis; cell growth; cation transmembrane transport. 32 alleles are reported. The phenotypes of these alleles manifest in: mitochondrion; salivary gland; embryonic/larval fat body; embryonic/larval anterior Malpighian tubule. The phenotypic classes of alleles include: phenotype; increased mortality during development; lethal; increased mortality."
FBgn0004227	nonA	0.327404643	0.401570553	0.999936032	NA	SFPQ;NONO;PSPC1	high;moderate;moderate	Maybe TF	NA	NA	"The gene no on or off transient A is referred to in FlyBase by the symbol Dmel\nonA (CG4211, FBgn0004227). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is X:16361569..16371547. It has the cytological map location 14B18-14C1. Protein features are: Hrp65/NonA; NOPS; RNA recognition motif domain. Its molecular function is described by: transcription regulatory region sequence-specific DNA binding; mRNA binding. It is involved in the biological process described with: mRNA splicing, via spliceosome; phototaxis; visual behavior; regulation of transcription, DNA-templated; male courtship behavior, veined wing generated song production; visual perception. 45 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: phenotype; increased mortality during development; lethal; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0264490	Eip93F	0.32741314	0.347567614	0.999936032	NA	LCORL;LCOR	high;moderate	DNA-binding with transcription factor activity(HTH_psq)	NA	NA	"The gene Ecdysone-induced protein 93F is referred to in FlyBase by the symbol Dmel\Eip93F (CG18389, FBgn0264490). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3R:21949114..22014539. It has the cytological map location 93F5-93F6. Protein features are: DNA binding HTH domain, Psq-type; Homeobox domain-like; Winged helix-turn-helix DNA-binding domain. Its molecular function is described by: DNA binding. It is involved in the biological process described with: positive regulation of transcription, DNA-templated; cellular response to hypoxia. 31 alleles are reported. The phenotypes of these alleles manifest in: abdominal segment; compound cell cluster organ; wing disc; dorsal mesothorax; salivary gland; larval tagma; imaginal disc; embryo; mesothoracic tergum; cell. The phenotypic classes of alleles include: phenotype; increased mortality during development; visible; lethal - all die before end of P-stage."
FBgn0036448	mop	0.327795046	0.357054697	0.999936032	NA	PTPN23;PDCD6IP	high;low	NA	NA	NA	"The gene myopic is referred to in FlyBase by the symbol Dmel\mop (CG9311, FBgn0036448). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:14769341..14776129. It has the cytological map location 70F4-70F5. Protein features are: ALIX V-shaped domain; BRO1 domain; PTP type protein phosphatase; Protein-tyrosine phosphatase-like. Its molecular function is unknown. It is involved in the biological process described with 14 unique terms, many of which group under: cellular protein modification process; retrograde transport, endosome to Golgi; positive regulation of establishment of protein localization; neurogenesis; antimicrobial humoral immune response mediated by antimicrobial peptide; central nervous system development; cell cycle process; antimicrobial humoral response; regulation of growth; vesicle-mediated transport between endosomal compartments; phosphate-containing compound metabolic process; neuron maturation; microtubule cytoskeleton organization; endocytic recycling; regulation of localization. 24 alleles are reported. The phenotypes of these alleles manifest in: neuron projection; imaginal disc; cell; adult head segment; adult thoracic segment; epithelium; integumentary system; somatodendritic compartment; apterous-expressing neuron of the lateral cluster of the thorax Ap4; brain; gonad. The phenotypic classes of alleles include: phenotype; increased mortality during development; lethal - all die before end of pupal stage; lethal - all die before end of P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0051087	CG31087	0.327970787	0.331890871	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31087 (FBgn0051087). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:25311027..25313833. It has the cytological map location 96D1. Protein features are: CHK kinase-like; Protein kinase-like domain; Protein of unknown function DUF227. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; ganglion mother cell. The phenotypic classes of alleles include: viable; visible; lethal; some die during pupal stage; partially lethal - majority die; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0051410	Npc2e	0.328015511	0.284973479	0.999936032	NA	NPC2	moderate	NA	NA	NA	"The gene Niemann-Pick type C-2e is referred to in FlyBase by the symbol Dmel\Npc2e (CG31410, FBgn0051410). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:10053332..10054348. It has the cytological map location 85F8. Protein features are: Immunoglobulin E-set; MD-2-related lipid-recognition domain. Its molecular function is described by: lipid antigen binding; lipoteichoic acid binding; lipopolysaccharide binding; peptidoglycan binding; sterol binding. It is involved in the biological process described with: sterol transport; peptidoglycan recognition protein signaling pathway. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during late larval stages.  "
FBgn0050423	CG30423	0.328053376	0.334457332	0.999936032	NA	LEPROT;LEPROTL1	high;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG30423 (FBgn0050423). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:24874976..24875865. It has the cytological map location 60E4. Protein features are: Vacuolar protein sorting 55. Its molecular function is described by: receptor binding. It is involved in the biological process described with: negative regulation of JAK-STAT cascade; late endosome to vacuole transport via multivesicular body sorting pathway; negative regulation of protein localization to cell surface. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0024291	Sirt1	0.328116509	0.393342411	0.999936032	NA	SIRT1	high	Chromatin regulation	NA	NA	"The gene Sirtuin 1 is referred to in FlyBase by the symbol Dmel\Sirt1 (CG5216, FBgn0024291). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:13165564..13169551. It has the cytological map location 34A7. Protein features are: DHS-like NAD/FAD-binding domain; Sirtuin family; Sirtuin family, catalytic core domain. Its molecular function is described by: histone deacetylase activity; NAD+ binding; protein deacetylase activity; NAD-dependent histone deacetylase activity; transcription factor binding. It is involved in the biological process described with 11 unique terms, many of which group under: response to alcohol; response to stimulus; programmed cell death; behavioral response to ethanol; anatomical structure development; feeding behavior; cellular response to chemical stimulus; aging; signal transduction; positive regulation of behavior. 35 alleles are reported. The phenotypes of these alleles manifest in: eye disc; dorso-lateral dopaminergic neuron; indirect flight muscle; ommatidium; wing; chromatin; nucleolus; eye. The phenotypic classes of alleles include: cell death defective; chemical resistant; increased mortality; stress response defective; feeding behavior defective; viable; phenotype; lethal - all die before end of prepupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0262035	CG42846	0.328536624	0.434186967	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG42846 (FBgn0262035). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:230971..231604. It has the cytological map location 61B2. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported.
FBgn0030510	CG12177	0.328745339	0.344277742	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG12177 (FBgn0030510). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is X:13677899..13680500. It has the cytological map location 12B2. Protein features are: Inosine/uridine-preferring nucleoside hydrolase; Inosine/uridine-preferring nucleoside hydrolase domain. Its molecular function is described by: purine nucleosidase activity. It is involved in the biological process described with: purine nucleoside catabolic process. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages.
FBgn0027780	U26	0.328865659	0.421343029	0.999936032	AASDH	AASDH	high	NA	NA	NA	"The gene U26 is referred to in FlyBase by the symbol Dmel\U26 (CG13401, FBgn0027780). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:8445861..8449576. It has the cytological map location 29C5. Protein features are: AMP-dependent synthetase/ligase; Pyrrolo-quinoline quinone beta-propeller repeat; Pyrrolo-quinoline quinone repeat; Pyrrolo-quinoline quinone-like domain; Quinoprotein alcohol dehydrogenase-like superfamily. Its molecular function is described by: acid-thiol ligase activity. It is involved in the biological process described with: fatty acid metabolic process. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0265536	CR44386	0.328894049	0.430767345	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44386 (FBgn0265536). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2R:17140579..17141194. It has the cytological map location 54A1. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0010194	Wnt5	0.329086489	0.370986671	0.999936032	NA	WNT5B;WNT5A;WNT4;WNT1;WNT9A;WNT10B;WNT7A;WNT2;WNT11;WNT7B;WNT2B;WNT6;WNT10A;WNT3;WNT16;WNT3A;WNT9B;WNT8A;WNT8B	high;moderate;moderate;low;low;low;low;low;low;low;low;low;low;moderate;low;moderate;low;moderate;low	NA	NA	NA	"The gene Wnt oncogene analog 5 is referred to in FlyBase by the symbol Dmel\Wnt5 (CG6407, FBgn0010194). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:18501401..18505405. It has the cytological map location 17B6-17C1. Protein features are: Wnt; Wnt protein, conserved site. Its molecular function is described by: receptor binding; frizzled binding; protein binding. It is involved in the biological process described with 11 unique terms, many of which group under: positive regulation of response to stimulus; cell fate commitment; cell surface receptor signaling pathway involved in cell-cell signaling; cell communication; muscle structure development; muscle organ development; animal organ development; determination of muscle attachment site; gland development; signal transduction. 27 alleles are reported. The phenotypes of these alleles manifest in: synaptic neuropil subdomain; eo-type sensillum; muscle cell; neuron projection; adult MBp lineage clone; dendrite; embryonic/larval hypodermal muscle; eo support cell; glomerulus; thoracic segment; presumptive embryonic/larval digestive system; anterior commissure. The phenotypic classes of alleles include: visible; phenotype; increased mortality during development; viable; increased mortality; locomotor behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the pupal period.  "
FBgn0036725	CG18265	0.329086489	0.370986671	0.999936032	NA	ZNF91	low	DNA-binding with transcription factor activity	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG18265 (FBgn0036725). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3L:17439401..17457461. It has the cytological map location 74C2-74C3. Protein features are: Zinc finger C2H2-type. Its molecular function is described by: nucleic acid binding. The biological processes in which it is involved are not known. 7 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: viable; visible; fertile; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 06-24 hour embryonic stages, during early larval stages.  "
FBgn0028583	lcs	0.329970039	0.285133359	0.999936032	NA	NA	NA	NA	NA	NA	"The gene la costa is referred to in FlyBase by the symbol Dmel\lcs (CG12794, FBgn0028583). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:21396727..21397316. It has the cytological map location 20A1. Its molecular function is described by: . It is involved in the biological process described with: . 5 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed in adults stages of both sexes.  "
FBgn0027592	MED15	0.330121764	0.399806059	0.999936032	NA	MED15	high	Co-factor	NA	NA	"The gene Mediator complex subunit 15 is referred to in FlyBase by the symbol Dmel\MED15 (CG4184, FBgn0027592). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:473013..476170. It has the cytological map location 21D1. Protein features are: Coactivator CBP, KIX domain; Mediator of RNA polymerase II transcription subunit 15. Its molecular function is described by: RNA polymerase II transcription cofactor activity. It is involved in the biological process described with: ovarian follicle cell development; transcription initiation from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter. 5 alleles are reported. The phenotypes of these alleles manifest in: wing disc; wing margin; wing; wing sensillum; wing vein L2. The phenotypic classes of alleles include: visible; viable; increased cell death; lethal - all die before end of pupal stage; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0029997	CG2258	0.330154547	0.42768811	0.999936032	NA	NCKIPSD	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG2258 (FBgn0029997). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is X:8094250..8102095. It has the cytological map location 7D6. Protein features are: Domain of unknown function DUF2013; SH3 domain; SPIN90, SH3 domain. Its molecular function is described by: myosin binding. The biological processes in which it is involved are not known. 6 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: viable; fertile; body color defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0011828	Pxn	0.330368936	0.389361401	0.999936032	PXDN	PXDN;PXDNL;TPO;EPX;MPO;LPO	high;moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"The gene Peroxidasin is referred to in FlyBase by the symbol Dmel\Pxn (CG12002, FBgn0011828). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (2 unique). Gene sequence location is 3L:2601455..2630064. It has the cytological map location 62E7. Protein features are: Haem peroxidase; Haem peroxidase, animal type; Immunoglobulin I-set; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold; Leucine-rich repeat; Leucine-rich repeat N-terminal domain; Leucine-rich repeat domain, L domain-like; Leucine-rich repeat, typical subtype; Peroxidasin; Peroxidasin, peroxidase domain; VWFC domain. Its molecular function is described by: peroxidase activity; heme binding. It is involved in the biological process described with: response to oxidative stress; oxidation-reduction process; extracellular matrix organization; phagocytosis. 14 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal - all die during P-stage; lethal; fertile; lethal - all die before end of pupal stage; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages.  "
FBgn0264947	CR44116	0.330461402	0.416479164	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44116 (FBgn0264947). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2L:8194509..8197049. It has the cytological map location 28F1. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0264776	CG44014	0.330537284	0.326075674	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG44014 (FBgn0264776). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:15507940..15508886. It has the cytological map location 88F7. Protein features are: Calycin. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable.
FBgn0051224	CG31224	0.330762727	0.40158637	0.999936032	NA	ZNF579;ZNF618;FIZ1;ZBTB44	low;low;low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31224 (FBgn0051224). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:18650121..18659309. It has the cytological map location 91B8. Protein features are: WD40/YVTN repeat-like-containing domain; Zinc finger C2H2-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: nucleic acid binding. The biological processes in which it is involved are not known. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during pupal stage; lethal - all die before end of pupal stage; lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0035715	CG10103	0.330802941	0.345744785	0.999936032	IST1	IST1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10103 (FBgn0035715). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (all unique). Gene sequence location is 3L:6754017..6756497. It has the cytological map location 65C3-65C4. Protein features are: Vacuolar protein sorting-associated protein Ist1. Its molecular function is described by: . It is involved in the biological process described with: protein transport; endosome transport via multivesicular body sorting pathway. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0034275	CG5002	0.331080961	0.337493638	0.999936032	NA	SLC26A11;SLC26A6;SLC26A5;SLC26A4;SLC26A3;SLC26A9;SLC26A1;SLC26A2;SLC26A8	high;moderate;moderate;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5002 (FBgn0034275). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:17750293..17753214. It has the cytological map location 54E8. Protein features are: SLC26A/SulP transporter; SLC26A/SulP transporter domain; STAS domain. Its molecular function is described by: secondary active sulfate transmembrane transporter activity; sulfate transmembrane transporter activity; chloride channel activity; oxalate transmembrane transporter activity; bicarbonate transmembrane transporter activity; anion:anion antiporter activity. It is involved in the biological process described with: regulation of membrane potential; sulfate transport; chloride transmembrane transport; bicarbonate transport; regulation of intracellular pH. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult male stages.  "
FBgn0264904	CR44095	0.331137652	0.427624911	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44095 (FBgn0264904). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3R:14568962..14569871. It has the cytological map location 88C6. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0003023	otu	0.331421862	0.195997513	0.999936032	NA	ALG13;OTUD4;OTUD4P1;OTUD1	moderate;moderate;moderate;moderate	NA	NA	NA	"The gene ovarian tumor is referred to in FlyBase by the symbol Dmel\otu (CG12743, FBgn0003023). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (2 unique). Gene sequence location is X:8485008..8489535. It has the cytological map location 7F1. Protein features are: OTU domain; Tudor domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: thiol-dependent ubiquitin-specific protease activity. It is involved in the biological process described with: germ cell development; female germ-line sex determination; oogenesis; protein deubiquitination; positive regulation of DNA endoreduplication. 66 alleles are reported. The phenotypes of these alleles manifest in: cytoplasmic part; follicle cell; intracellular; chorionic specialization; nurse cell ring canal; female germline cell; membrane-enclosed lumen; organelle; epithelium; egg. The phenotypic classes of alleles include: phenotype; fertile; increased mortality; sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed in adult female stages.  "
FBgn0047351	CG31468	0.331421862	0.195997513	0.999936032	NA	ODF3L2;ODF3L1	low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31468 (FBgn0047351). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:23699328..23700354. It has the cytological map location 95A8. Protein features are: Sperm-tail PG-rich repeat. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0263864	Dark	0.331806368	0.428026962	0.999936032	NA	APAF1	high	NA	NA	NA	"The gene Death-associated APAF1-related killer is referred to in FlyBase by the symbol Dmel\Dark (CG6829, FBgn0263864). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:17020027..17026703. It has the cytological map location 53E4-54A2. Protein features are: NB-ARC; P-loop containing nucleoside triphosphate hydrolase; WD40 repeat; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: cysteine-type endopeptidase activity involved in apoptotic signaling pathway; ADP binding; CARD domain binding; ATP binding; cysteine-type endopeptidase activator activity involved in apoptotic process. It is involved in the biological process described with 24 unique terms, many of which group under: organic acid catabolic process; compound eye retinal cell programmed cell death; cellular homeostasis; cell morphogenesis involved in neuron differentiation; response to starvation; regulation of humoral immune response; male gamete generation; melanin metabolic process; regulation of biological quality; response to abiotic stimulus; multi-organism process; lipid homeostasis; neurogenesis; anatomical structure homeostasis; response to nutrient levels; central nervous system morphogenesis; negative regulation of response to stimulus. 62 alleles are reported. The phenotypes of these alleles manifest in: midline glial cell; individualization stage spermatid; melanotic mass; embryonic head; neuron projection; spermatid; male germline cell; epithelial cell; dendrite; midline crossing tract; intracellular; glial cell; embryonic neuroblast; pigment cell; embryonic brain; eo neuron; embryonic tagma; eye-antennal disc; inter-ommatidial precursor cell. The phenotypic classes of alleles include: phenotype; increased mortality during development; lethal; cell death defective."
FBgn0264744	CG44002	0.331840312	0.376302794	0.999936032	NA	ZNF501;ZNF771;ZNF648	low;low;low	DNA-binding with transcription factor activity	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG44002 (FBgn0264744). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:3169820..3171092. It has the cytological map location 23D4. Protein features are: Zinc finger C2H2-type; Zinc finger, AD-type. Its molecular function is described by: DNA binding; zinc ion binding. It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable."
FBgn0265450	CR44350	0.332061358	0.23613716	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44350 (FBgn0265450). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3R:22823686..22827260. It has the cytological map location 94C9. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0005660	Ets21C	0.332461889	0.41608288	0.999936032	NA	FLI1;FEV;ERG;ETV3;ERF;ETV3L	moderate;moderate;moderate;moderate;moderate;moderate	DNA-binding with transcription factor activity(Ets)	NA	NA	"The gene Ets at 21C is referred to in FlyBase by the symbol Dmel\Ets21C (CG2914, FBgn0005660). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 2L:544925..552923. It has the cytological map location 21E2. Protein features are: Ets domain; Pointed domain; Sterile alpha motif/pointed domain; Winged helix-turn-helix DNA-binding domain. Its molecular function is described by: RNA polymerase II transcription factor activity, sequence-specific DNA binding; sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription from RNA polymerase II promoter; defense response to bacterium; dendrite morphogenesis. 9 alleles are reported. The phenotypes of these alleles manifest in: wing; intestinal stem cell; adult midgut. The phenotypic classes of alleles include: fertile; stress response defective; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0052228	CG32228	0.332796457	0.283828638	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32228 (FBgn0052228). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:20265814..20268800. It has the cytological map location 77B1. Its molecular function is described by: . It is involved in the biological process described with: . 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed at stages throughout the pupal period, in adult male stages.  "
FBgn0051104	CG31104	0.333096893	0.322603141	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG31104 (FBgn0051104). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:25285473..25286974. It has the cytological map location 96C9. Protein features are: CHK kinase-like; Protein kinase-like domain; Protein of unknown function DUF227. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed in adults stages of both sexes.
FBgn0050154	CG30154	0.334201924	0.364956539	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG30154 (FBgn0050154). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:20533359..20533934. It has the cytological map location 57A5. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die during embryonic stage; viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed at stages throughout the pupal period.
FBgn0035262	CG18171	0.33434997	0.340396684	0.999936032	NA	TCTE1	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG18171 (FBgn0035262). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:1720616..1723153. It has the cytological map location 62B1. Protein features are: Leucine-rich repeat domain, L domain-like. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed in adult male stages.  "
FBgn0034578	CG15653	0.3345358	0.405527436	0.999936032	NA	COA1	moderate	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG15653 (FBgn0034578). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:21059780..21060547. It has the cytological map location 57B16. Protein features are: Cytochrome oxidase assembly protein 1. Its molecular function is described by: structural constituent of ribosome; RNA binding. It is involved in the biological process described with: translation. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0037375	kat-60L1	0.334741029	0.267402121	0.999936032	NA	KATNAL1;KATNA1;KATNAL2	moderate;moderate;low	NA	NA	NA	"The gene katanin p60-like 1 is referred to in FlyBase by the symbol Dmel\kat-60L1 (CG1193, FBgn0037375). It is a protein_coding_gene from Drosophila melanogaster. It has 8 annotated transcripts and 8 polypeptides (4 unique). Gene sequence location is 3R:5781762..5787465. It has the cytological map location 83C3-83C4. Protein features are: AAA+ ATPase domain; ATPase, AAA-type, conserved site; ATPase, AAA-type, core; Katanin p60 subunit A1; P-loop containing nucleoside triphosphate hydrolase; Vps4 oligomerisation, C-terminal. Its molecular function is described by: ATPase activity; microtubule binding; microtubule-severing ATPase activity; ATP binding. It is involved in the biological process described with: microtubule-based process; positive regulation of dendrite morphogenesis; microtubule severing; neuron remodeling. 9 alleles are reported. The phenotypes of these alleles manifest in: dendrite; chaeta; class IV dendritic arborizing neuron; trichogen cell; dorsal multidendritic neuron ddaC. The phenotypic classes of alleles include: pain response defective; heat stress response defective; phenotype; stress response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed in adult male stages.  "
FBgn0036306	CG10973	0.334898771	0.38694076	0.999936032	HSPBP1	HSPBP1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10973 (FBgn0036306). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:12753239..12754774. It has the cytological map location 69E1. Protein features are: Armadillo-like helical; Armadillo-type fold; Nucleotide exchange factor Fes1. Its molecular function is described by: enzyme inhibitor activity. It is involved in the biological process described with: . 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, in adult female stages.  "
FBgn0029864	CG15894	0.334927198	0.251215764	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15894 (FBgn0029864). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is X:6309212..6329828. It has the cytological map location 5E8-5F1. Its molecular function is unknown. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages.  "
FBgn0263967	CR43723	0.334927198	0.251215764	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR43723 (FBgn0263967). It is a non_protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts. Gene sequence location is 2R:7492364..7493497. It has the cytological map location 43C5. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0036386	CG8833	0.335168678	0.405260583	0.999936032	NA	GPATCH1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8833 (FBgn0036386). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:13925882..13929000. It has the cytological map location 70C5. Protein features are: G patch domain-containing protein, N-terminal; G-patch domain. Its molecular function is described by: nucleic acid binding. It is involved in the biological process described with: mRNA processing; mRNA splicing, via spliceosome. 10 alleles are reported. The phenotype of these alleles manifest in: germline cell. The phenotypic classes of alleles include: viable; short lived; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during early pupal stages, in adult female stages.  "
FBgn0039925	Kif3C	0.335539056	0.403626583	0.999936032	NA	KIF17;KIF3A	high;low	NA	NA	NA	"The gene Kinesin family member 3C is referred to in FlyBase by the symbol Dmel\Kif3C (CG17461, FBgn0039925). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 4:1147466..1169239. It has the cytological map location 102F8. Protein features are: Kinesin motor domain; Kinesin motor domain, conserved site; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: ATP binding; microtubule binding; microtubule motor activity; ATPase activity; ATP-dependent microtubule motor activity, minus-end-directed. It is involved in the biological process described with: neuron projection morphogenesis; microtubule-based movement. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very low expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0052407	CG32407	0.336092138	0.329084836	0.999936032	NA	MOSPD2	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32407 (FBgn0052407). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:5922055..5923567. It has the cytological map location 64F5. Protein features are: CRAL-TRIO lipid binding domain; CRAL/TRIO, N-terminal domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 06-18 hour embryonic stages.  "
FBgn0042179	CG18869	0.336181701	0.340010964	0.999936032	NA	UGT1A3;UGT2B10;UGT1A1;UGT3A1;UGT8;UGT2B4;UGT2B15;UGT2B28;UGT2A2;UGT3A2;UGT2B17;UGT2B11;UGT2A3;UGT2B7	moderate;moderate;low;low;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG18869 (FBgn0042179). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:4059770..4061923. It has the cytological map location 64A5. Protein features are: UDP-glucuronosyl/UDP-glucosyltransferase. Its molecular function is described by: glucuronosyltransferase activity. It is involved in the biological process described with: metabolic process. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; flight defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0003308	ry	0.336662555	0.386950102	0.999936032	XDH	XDH;AOX1	high;moderate	NA	NA	NA	"The gene rosy is referred to in FlyBase by the symbol Dmel\ry (CG7642, FBgn0003308). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:13032528..13038020. It has the cytological map location 87D9. Protein features are: 2Fe-2S ferredoxin, iron-sulphur binding site; 2Fe-2S ferredoxin-type iron-sulfur binding domain; Aldehyde oxidase/xanthine dehydrogenase; Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead; Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding; Beta-grasp domain; CO dehydrogenase flavoprotein, C-terminal; CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2; FAD-binding, type 2; FAD-binding, type 2, subdomain 1; Molybdopterin dehydrogenase, FAD-binding; Oxidoreductase, molybdopterin binding site; Xanthine dehydrogenase, small subunit; [2Fe-2S]-binding. Its molecular function is described by: electron carrier activity; 2 iron, 2 sulfur cluster binding; molybdopterin cofactor binding; xanthine dehydrogenase activity; flavin adenine dinucleotide binding; oxidoreductase activity, acting on CH-OH group of donors; oxidoreductase activity, acting on the aldehyde or oxo group of donors; iron ion binding; xanthine oxidase activity. It is involved in the biological process described with: pyrimidine nucleobase metabolic process; response to ethanol; glycerophospholipid metabolic process; xanthine catabolic process; tryptophan metabolic process; compound eye pigmentation; oxidation-reduction process; determination of adult lifespan; purine nucleobase metabolic process; arginine metabolic process. 360 alleles are reported. The phenotypes of these alleles manifest in: pigment cell; Malpighian tubule; embryonic/larval Malpighian tubule. The phenotypic classes of alleles include: partially lethal - majority die; viable; phenotype; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0085257	CG34228	0.336749299	0.365717998	0.999936032	NA	SMIM12	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG34228 (FBgn0085257). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:11651857..11652339. It has the cytological map location 48B4. Protein features are: UPF0767 family. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed during early larval stages, during late pupal stages.  "
FBgn0032516	Ing5	0.336952572	0.392616919	0.999936032	NA	ING4;ING5;ING3;ING2;ING1	high;moderate;moderate;moderate;low	NA	NA	NA	"The gene Inhibitor of growth family member 5 is referred to in FlyBase by the symbol Dmel\Ing5 (CG9293, FBgn0032516). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:13385848..13387312. It has the cytological map location 34B9. Protein features are: ING family; Inhibitor of growth protein, N-terminal histone-binding; Zinc finger, FYVE/PHD-type; Zinc finger, PHD-finger; Zinc finger, PHD-type; Zinc finger, PHD-type, conserved site; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: histone acetyltransferase activity (H3-K23 specific). It is involved in the biological process described with: histone H3 acetylation; regulation of cell cycle. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0085415	CG34386	0.337037999	0.390001774	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG34386 (FBgn0085415). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:18062415..18093628. It has the cytological map location 55B2-55B4. Protein features are: WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: flightless; viable; lethal - all die before end of pupal stage; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0085736	CG40472	0.33707566	0.341302269	0.999936032	NA	NDUFB2	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG40472 (FBgn0085736). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:24927130..24927710. Protein features are: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2. Its molecular function is described by: . It is involved in the biological process described with: . One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.  "
FBgn0004880	scrt	0.337395654	0.349207976	0.999936032	NA	SCRT1;SCRT2;SNAI3;SNAI1;SNAI2	high;moderate;low;low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene scratch is referred to in FlyBase by the symbol Dmel\scrt (CG1130, FBgn0004880). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:3983896..3994003. It has the cytological map location 64A2-64A3. Protein features are: Zinc finger C2H2-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: nucleic acid binding. It is involved in the biological process described with: dendrite morphogenesis; negative regulation of transcription from RNA polymerase II promoter. 16 alleles are reported. The phenotypes of these alleles manifest in: eye; microchaeta; eye photoreceptor cell; posterior crossvein; macrochaeta; neuron; anterior crossvein; photoreceptor cell; pigment cell; wing. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; partially lethal; behavior defective; some die during pupal stage; uncoordinated; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 06-18 hour embryonic stages.  "
FBgn0038693	unc79	0.337518126	0.404052913	0.999936032	NA	UNC79	high	NA	NA	NA	"The gene uncoordinated 79 is referred to in FlyBase by the symbol Dmel\unc79 (CG5237, FBgn0038693). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (all unique). Gene sequence location is 3R:19230764..19246130. It has the cytological map location 91F12. Protein features are: Armadillo-like helical; Armadillo-type fold; UNC79. Its molecular function is described by: . It is involved in the biological process described with: locomotor rhythm; response to anesthetic. 14 alleles are reported. The phenotype of these alleles manifest in: adult abdomen. The phenotypic classes of alleles include: locomotor behavior defective; chemical sensitive; fertile; circadian behavior defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0033987	ckn	0.33776529	0.377553142	0.999936032	NA	CASKIN1;CASKIN2	high;moderate	NA	NA	NA	"The gene caskin is referred to in FlyBase by the symbol Dmel\ckn (CG12424, FBgn0033987). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is 2R:14963292..14980795. It has the cytological map location 51D6. Protein features are: Caskin1/2, SAM repeat 1; Caskin1/2, SAM repeat 2; Sterile alpha motif domain; Sterile alpha motif/pointed domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: protein phosphatase binding; signaling adaptor activity. It is involved in the biological process described with: transmembrane receptor protein tyrosine phosphatase signaling pathway; axonogenesis; axon guidance. 25 alleles are reported. The phenotypes of these alleles manifest in: fascicle; intersegmental nerve branch ISNb of A1-7; intersegmental nerve; axon. The phenotypic classes of alleles include: viable; lethal; some die during pupal stage; partially lethal; learning defective; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period.  "
FBgn0052479	Usp10	0.338075744	0.354779901	0.999936032	NA	USP10	high	NA	NA	NA	"The gene Ubiquitin specific protease 10 is referred to in FlyBase by the symbol Dmel\Usp10 (CG32479, FBgn0052479). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:871899..895313. It has the cytological map location 61D2-61D4. Protein features are: Peptidase C19, ubiquitin carboxyl-terminal hydrolase; Ubiquitin specific protease domain; Ubiquitin specific protease, conserved site. Its molecular function is described by: thiol-dependent ubiquitin-specific protease activity. It is involved in the biological process described with: ubiquitin-dependent protein catabolic process; protein deubiquitination; positive regulation of Notch signaling pathway. 28 alleles are reported. The phenotypes of these alleles manifest in: Z disc; scutellar bristle; sarcomere; wing. The phenotypic classes of alleles include: fertile; lethal; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0034599	hng1	0.338089888	0.388711117	0.999936032	NA	NA	NA	DNA-binding with transcription factor activity(BESS)	NA	NA	"The gene hinge1 is referred to in FlyBase by the symbol Dmel\hng1 (CG9437, FBgn0034599). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:21168930..21170010. It has the cytological map location 57C7. Protein features are: BESS motif; MADF domain. Its molecular function is described by: DNA binding. The biological processes in which it is involved are not known. 8 alleles are reported. The phenotypes of these alleles manifest in: wing hinge; wing blade. The phenotypic classes of alleles include: size defective; flightless; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, during early pupal stages, in stages of adults of both sexes.  "
FBgn0028499	CG7985	0.338245129	0.420610088	0.999936032	HEXDC	HEXDC	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7985 (FBgn0028499). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:18199857..18215001. It has the cytological map location 90F7. Protein features are: Glycoside hydrolase superfamily. Its molecular function is unknown. The biological processes in which it is involved are not known. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0267160	CR45600	0.338245129	0.420610088	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45600 (FBgn0267160). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3R:15136985..15140121. It has the cytological map location 88E2. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0031772	CG13994	0.338292011	0.35902118	0.999936032	NA	PPP1R11	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG13994 (FBgn0031772). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:6062989..6063671. It has the cytological map location 26B4. Protein features are: Protein phosphatase inhibitor. Its molecular function is described by: protein serine/threonine phosphatase inhibitor activity; protein phosphatase 1 binding. It is involved in the biological process described with: negative regulation of phosphoprotein phosphatase activity; defense response to Gram-negative bacterium; positive regulation of innate immune response. 4 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval brain. The phenotypic classes of alleles include: flightless; lethal; viable; some die during pupal stage; lethal - all die before end of pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed in adult male stages.
FBgn0051248	CG31248	0.33830519	0.356275755	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG31248 (FBgn0051248). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:7129320..7130908. It has the cytological map location 84C4. Protein features are: Acyl-CoA N-acyltransferase. Its molecular function is described by: N-acetyltransferase activity. It is involved in the biological process described with: nitrogen compound metabolic process. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed in adult male stages.
FBgn0003275	RpII18	0.338671966	0.324969676	0.999936032	NA	POLR2F	high	NA	NA	NA	"The gene RNA polymerase II 18kD subunit is referred to in FlyBase by the symbol Dmel\RpII18 (CG1163, FBgn0003275). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:5371795..5372397. It has the cytological map location 83A1. Protein features are: Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit; DNA-directed RNA polymerase, 14-18kDa subunit, conserved site; DNA-directed RNA polymerase, subunit  RPB6; RNA polymerase subunit, RPB6/omega; RNA polymerase, subunit omega/K/RPB6. Its molecular function is described by: DNA binding; RNA polymerase II activity; RNA polymerase III activity; RNA polymerase I activity. It is involved in the biological process described with: transcription from RNA polymerase II promoter; mitotic G2 DNA damage checkpoint. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: lethal - all die during larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0267521	18SrRNA-Psi:CR45861	0.338770405	0.312665786	0.999936032	NA	NA	NA	NA	NA	NA	"The gene 18S ribosomal RNA pseudogene:CR45861 is referred to in FlyBase by the symbol Dmel\18SrRNA-‘Â:CR45861 (CR45861, FBgn0267521). It is a pseudogene_attribute from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is X:23280998..23282931. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported."
FBgn0028534	CG7916	0.338810743	0.31195414	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7916 (FBgn0028534). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:13846752..13847799. It has the cytological map location 34D7. Protein features are: Haemolymph juvenile hormone binding. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the larval period, during early pupal stages, in stages of adults of both sexes.  "
FBgn0267761	CR46092	0.338962885	0.386414603	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR46092 (FBgn0267761). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3R:23957305..23958388. It has the cytological map location 95D1. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0036038	defl	0.339243249	0.396220361	0.999936032	INTS7	INTS7	high	NA	NA	NA	"The gene deflated is referred to in FlyBase by the symbol Dmel\defl (CG18176, FBgn0036038). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:9723423..9726706. It has the cytological map location 67C5. Protein features are: Armadillo-like helical; Armadillo-type fold; Integrator complex subunit 7. Its molecular function is described by: . It is involved in the biological process described with: snRNA 3'-end processing; snRNA processing. 11 alleles are reported. The phenotypes of these alleles manifest in: chorion; dorsal appendage; humeral bristle; mesothoracic tergum; adult abdomen; wing; wing vein L5; anterior crossvein; tergite; genitalia. The phenotypic classes of alleles include: female fertile; viable; visible; some die during second instar larval stage; lethal - all die before end of second instar larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0262081	Csk	0.339564106	0.347919297	0.999936032	NA	CSK;MATK	high;moderate	NA	NA	NA	"The gene C-terminal Src kinase is referred to in FlyBase by the symbol Dmel\Csk (CG42317, FBgn0262081). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (3 unique). Gene sequence location is 3R:11633278..11650706. It has the cytological map location 86E13. Protein features are: CSK-like, SH2 domain; Protein kinase domain; Protein kinase, ATP binding site; Protein kinase-like domain; SH2 domain; Serine-threonine/tyrosine-protein kinase, catalytic domain; Tyrosine-protein kinase CSK; Tyrosine-protein kinase, active site; Tyrosine-protein kinase, catalytic domain. Its molecular function is described by: ATP binding; non-membrane spanning protein tyrosine kinase activity; protein tyrosine kinase activity; receptor binding. It is involved in the biological process described with 14 unique terms, many of which group under: negative regulation of biological process; cell-cell junction organization; sexual reproduction; regulation of programmed cell death; regulation of cell communication; immune response; cellular response to stimulus; tissue homeostasis; germarium-derived egg chamber formation; negative regulation of growth; enzyme linked receptor protein signaling pathway; multicellular organismal homeostasis; response to stimulus; establishment or maintenance of bipolar cell polarity; cellular component maintenance; cell death; localization. 33 alleles are reported. The phenotypes of these alleles manifest in: wing vein L4; alimentary canal; inter-ommatidial precursor cell; cuboidal/columnar epithelium; anterior crossvein; stem cell; ommatidium; cell component; female organism; neuromuscular junction; intestinal stem cell of posterior adult midgut epithelium. The phenotypic classes of alleles include: size defective; lethal - all die before end of P-stage; cell death defective; phenotype; increased mortality."
FBgn0024510	dlt	0.339601325	0.415590809	0.999936032	NA	CDAN1	high	Maybe TF	NA	NA	"The gene discs lost is referred to in FlyBase by the symbol Dmel\dlt (CG32315, FBgn0024510). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:1789631..1795328. It has the cytological map location 62B4. Protein features are: Codanin-1, C-terminal domain. Its molecular function is unknown. It is involved in the biological process described with: olfactory behavior; imaginal disc morphogenesis; lateral inhibition; regulation of cell proliferation; morphogenesis of a polarized epithelium. 26 alleles are reported. The phenotypes of these alleles manifest in: cell cluster organ; external sensillum; embryonic/larval salivary gland; adult head; trichogen cell; ovariole; embryonic/larval digestive system; compound sense organ; somatic cell; germline cyst. The phenotypic classes of alleles include: increased mortality during development; phenotype; lethal; lethal - all die before end of pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0011802	Gem3	0.339610921	0.417290454	0.999936032	NA	DDX20	high	NA	NA	NA	"The gene Gemin3 is referred to in FlyBase by the symbol Dmel\Gem3 (CG6539, FBgn0011802). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:10459081..10463101. It has the cytological map location 67E3. Protein features are: DEAD/DEAH box helicase domain; Helicase superfamily 1/2, ATP-binding domain; Helicase, C-terminal; P-loop containing nucleoside triphosphate hydrolase; RNA helicase, DEAD-box type, Q motif. Its molecular function is described by: ATP binding; ATP-dependent RNA helicase activity; nucleic acid binding; RNA helicase activity. It is involved in the biological process described with: flight behavior; adult locomotory behavior; neuromuscular junction development; spliceosomal snRNP assembly; RNA secondary structure unwinding; ribonucleoprotein complex assembly. 14 alleles are reported. The phenotypes of these alleles manifest in: head; embryonic/larval neuromuscular junction; wing; indirect flight muscle; trichogen cell; leg. The phenotypic classes of alleles include: locomotor behavior defective; lethal - all die before end of P-stage; phenotype; increased mortality during development; developmental rate defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0032120	CG33298	0.339800645	0.348356263	0.999936032	NA	ATP10D;ATP10B;ATP10A;ATP8B2;ATP8B4	high;high;moderate;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG33298 (FBgn0032120). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 2L:9495474..9520696. It has the cytological map location 30B5-30B10. Protein features are: HAD-like domain; P-type ATPase; P-type ATPase,  transmembrane domain; P-type ATPase, A  domain; P-type ATPase, C-terminal; P-type ATPase, N-terminal; P-type ATPase, cytoplasmic domain N; P-type ATPase, phosphorylation site; P-type ATPase, subfamily IV. Its molecular function is described by: ATP binding; magnesium ion binding; phospholipid-translocating ATPase activity. It is involved in the biological process described with: phospholipid translocation; Golgi organization; response to endoplasmic reticulum stress; intracellular protein transport. 22 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, in adult female stages.  "
FBgn0263413	CR43459	0.339821105	0.362702168	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR43459 (FBgn0263413). It is a non_protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts. Gene sequence location is 3R:10093761..10101356. It has the cytological map location 85F10. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0039648	CG14515	0.340459217	0.208206248	0.999936032	NA	FRRS1	moderate	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG14515 (FBgn0039648). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:29197556..29199211. It has the cytological map location 99A1. Protein features are: Reeler domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: short lived; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late pupal stages.
FBgn0041184	Socs36E	0.341104426	0.34716257	0.999936032	NA	SOCS4;SOCS5	high;moderate	NA	NA	NA	"The gene Suppressor of cytokine signaling at 36E is referred to in FlyBase by the symbol Dmel\Socs36E (CG15154, FBgn0041184). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:18138675..18152417. It has the cytological map location 36E6. Protein features are: SH2 domain; SOCS box domain; Suppressor of cytokine signalling 5. Its molecular function is described by: cytokine receptor binding; protein kinase inhibitor activity. It is involved in the biological process described with 18 unique terms, many of which group under: dedifferentiation; notum morphogenesis; behavior; regulation of ERBB signaling pathway; stem cell population maintenance; sexual reproduction; pigmentation; ameboidal-type cell migration; regulation of cell fate commitment; neurological system process; negative regulation of protein kinase activity. 28 alleles are reported. The phenotypes of these alleles manifest in: sensory system; epithelial cell; somatic cell of testis; male reproductive system; crossvein; sensory neuron; pigment cell; developing material anatomical entity; male organism; stem cell. The phenotypic classes of alleles include: visible; increased mortality during development; phenotype; memory defective; increased mortality; immune response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0020388	Gcn5	0.341217254	0.354601746	0.999936032	NA	KAT2A;KAT2B	high;moderate	Chromatin regulation	NA	NA	"The gene Gcn5 acetyltransferase is referred to in FlyBase by the symbol Dmel\Gcn5 (CG4107, FBgn0020388). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:12521129..12524014. It has the cytological map location 69C4. Protein features are: Acyl-CoA N-acyltransferase; Bromodomain; Bromodomain, conserved site; GNAT domain; Histone acetyltransferase GCN5/PCAF; PCAF, N-terminal. Its molecular function is described by: H4 histone acetyltransferase activity; protein binding; chromatin binding; H3 histone acetyltransferase activity; histone acetyltransferase activity. It is involved in the biological process described with: histone H4 acetylation; histone acetylation; chromatin remodeling; histone H3 acetylation; dendrite morphogenesis; muscle organ development; regulation of transcription, DNA-templated. 21 alleles are reported. The phenotypes of these alleles manifest in: neuron; dorsal thoracic disc; intracellular organelle part; adult metathoracic segment; eye photoreceptor cell; adult midgut; compartment; non-membrane-bounded organelle; germline cell; digestive system; larval segment; photoreceptor cell; cell. The phenotypic classes of alleles include: increased mortality during development; phenotype; increased mortality; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0003660	Syb	0.341366992	0.312613501	0.999936032	NA	VAMP2;VAMP1;VAMP3;VAMP4;VAMP8;VAMP5	moderate;high;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene Synaptobrevin is referred to in FlyBase by the symbol Dmel\Syb (CG12210, FBgn0003660). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 2R:10249435..10252417. It has the cytological map location 46F8. Protein features are: Synaptobrevin. Its molecular function is described by: SNARE binding; SNAP receptor activity. It is involved in the biological process described with: synaptic vesicle docking; neurotransmitter secretion; lumen formation, open tracheal system; vesicle-mediated transport; vesicle fusion; exocytosis. 18 alleles are reported. The phenotypes of these alleles manifest in: ommatidium; embryonic/larval tracheal system; eye. The phenotypic classes of alleles include: some die during larval stage; lethal - all die before end of pupal stage; some die during pupal stage; lethal; developmental rate defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed within 06-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0051694	CG31694	0.341563731	0.333364944	0.999936032	NA	IFRD2;IFRD1	high;high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31694 (FBgn0051694). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:2868627..2874489. It has the cytological map location 23B7-23B8. Protein features are: Armadillo-like helical; Armadillo-type fold; Interferon-related developmental regulator, C-terminal; Interferon-related developmental regulator, N-terminal. Its molecular function is unknown. It is involved in the biological process described with: positive regulation of JAK-STAT cascade. 17 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0267665	CR46003	0.341566464	0.337723079	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR46003 (FBgn0267665). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3L:10286900..10307954. It has the cytological map location 67D12-67D13. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0261710	nocte	0.341589678	0.38092463	0.999936032	NA	PRRC2A;PRRC2C;PRRC2B	high;moderate;moderate	NA	NA	NA	"The gene no circadian temperature entrainment is referred to in FlyBase by the symbol Dmel\nocte (CG17255, FBgn0261710). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is X:10461865..10474675. It has the cytological map location 9C5-9D1. Protein features are: BAT2, N-terminal; Peptidase C65, otubain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: . It is involved in the biological process described with: entrainment of circadian clock; temperature compensation of the circadian clock. 11 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: uncoordinated; locomotor rhythm defective; lethal."
FBgn0032717	CG10600	0.34211956	0.345361513	0.999936032	NA	RSBN1L;RSBN1	high;high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10600 (FBgn0032717). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 2L:18833710..18839679. It has the cytological map location 37B1. Protein features are: RSBN1/Dpy-21. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0015572	alpha-Est4	0.342139732	0.388479499	0.999936032	NA	BCHE;CES4A;CES2;NLGN2;CES5A;CES1;CEL;NLGN4X;NLGN1;NLGN3;NLGN4Y;CES3	low;low;low;low;low;low;low;low;low;low;low;low	NA	NA	NA	"The gene ‘±-Esterase-4 is referred to in FlyBase by the symbol Dmel\‘±-Est4 (CG1082, FBgn0015572). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:7536687..7538615. It has the cytological map location 84D9. Protein features are: Alpha/Beta hydrolase fold; Carboxylesterase, type B. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed during late larval stages.  "
FBgn0039538	CG12883	0.342307012	0.348740987	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12883 (FBgn0039538). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:27679291..27680336. It has the cytological map location 98B1. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0032401	Plzf	0.342405897	0.400582373	0.999936032	NA	ZBTB17;MYNN;ZBTB24	high;high;high	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene Promyelocytic leukemia zinc finger is referred to in FlyBase by the symbol Dmel\Plzf (CG6792, FBgn0032401). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:12046711..12048918. It has the cytological map location 33B11. Protein features are: BTB/POZ domain; SKP1/BTB/POZ domain; Zinc finger C2H2-type. Its molecular function is described by: nucleic acid binding. It is involved in the biological process described with: Ras protein signal transduction; imaginal disc-derived wing vein specification. 13 alleles are reported. The phenotype of these alleles manifest in: wing vein. The phenotypic classes of alleles include: partially lethal - majority die; some die during embryonic stage; viable; lethal - all die before end of embryonic stage; short lived; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0020440	Fak	0.342914272	0.364703851	0.999936032	PTK2	PTK2;PTK2B	high;moderate	NA	NA	NA	"The gene Focal adhesion kinase is referred to in FlyBase by the symbol Dmel\Fak (CG10023, FBgn0020440). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (3 unique). Gene sequence location is 2R:19430659..19437259. It has the cytological map location 56D5. Protein features are: Band 4.1 domain; FERM central domain; FERM domain; FERM/acyl-CoA-binding protein, 3-helical bundle; Focal adhesion kinase, targeting (FAT) domain; PH domain-like; Protein kinase domain; Protein kinase-like domain; Serine-threonine/tyrosine-protein kinase, catalytic domain; Tyrosine-protein kinase, active site; Tyrosine-protein kinase, catalytic domain; Ubiquitin-related domain. Its molecular function is described by: receptor binding; protein tyrosine kinase activity; non-membrane spanning protein tyrosine kinase activity; signal transducer activity; ATP binding. It is involved in the biological process described with: innate immune response; signal complex assembly; cytoskeletal anchoring at plasma membrane; peptidyl-tyrosine autophosphorylation; negative regulation of synaptic growth at neuromuscular junction; cell differentiation; negative regulation of epidermal growth factor receptor signaling pathway; regulation of cell proliferation; negative regulation of MAP kinase activity; protein phosphorylation. 20 alleles are reported. The phenotypes of these alleles manifest in: bouton; neuromuscular junction; lateral longitudinal fascicle; subretinal glial cell; medial longitudinal fascicle; muscle attachment site; wing; synapse; NMJ bouton; embryonic/larval optic stalk. The phenotypic classes of alleles include: neuroanatomy defective; fertile; neurophysiology defective; visible; female semi-sterile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 12-18 embryonic stages.  "
FBgn0052350	Vps11	0.34300236	0.351633522	0.999936032	NA	VPS11	high	NA	NA	NA	"The gene Vacuolar protein sorting 11 is referred to in FlyBase by the symbol Dmel\Vps11 (CG32350, FBgn0052350). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:23147656..23150499. It has the cytological map location 80D3. Protein features are: Tetratricopeptide-like helical domain; Vacuolar protein sorting-associated protein 11; Zinc finger, RING-type. Its molecular function is described by: ubiquitin-protein transferase activity; protein binding, bridging; zinc ion binding. It is involved in the biological process described with: regulation of SNARE complex assembly; endosome organization; lysosome organization; lysosomal transport; histone ubiquitination; autophagosome maturation; vesicle docking involved in exocytosis; cellular response to starvation; endosomal transport. 3 alleles are reported. The phenotypes of these alleles manifest in: vacuole; mesothoracic tergum; embryonic/larval fat body; late endosome; autophagosome; embryonic/larval garland cell; autolysosome. The phenotypic classes of alleles include: viable; body color defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0013684	mt:ND5	0.343199531	0.307230667	0.999936032	NA	ND5	high	NA	transmembrane protein	NA	"The gene mitochondrial NADH-ubiquinone oxidoreductase chain 5 is referred to in FlyBase by the symbol Dmel\mt:ND5 (CG34083, FBgn0013684). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is mitochondrion_genome:6409..8125. Protein features are: NADH dehydrogenase subunit 5, C-terminal; NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal; NADH-plastoquinone oxidoreductase, chain 5 subgroup; NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit. Its molecular function is described by: NADH dehydrogenase (ubiquinone) activity. It is involved in the biological process described with: ATP synthesis coupled electron transport. No alleles are reported. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed at stages throughout embryogenesis, during early pupal stages, in stages of adults of both sexes.  "
FBgn0261611	CG42700	0.343286782	0.37172732	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG42700 (FBgn0261611). It is a protein_coding_gene from Drosophila melanogaster. It has 8 annotated transcripts and 8 polypeptides (6 unique). Gene sequence location is 2R:12279771..12300795. It has the cytological map location 48F6. Protein features are: WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during pupal stage; lethal - all die before end of pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during late pupal stages.
FBgn0037134	CG7407	0.343420427	0.365347777	0.999936032	NA	MXRA7	low	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG7407 (FBgn0037134). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:21823461..21824571. It has the cytological map location 78F3. Protein features are: Matrix-remodeling-associated protein 7. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0035254	CG7974	0.343715841	0.403856192	0.999936032	C9orf78	C9orf78	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG7974 (FBgn0035254). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:1665138..1666594. It has the cytological map location 62A10. Protein features are: Hepatocellular carcinoma-associated antigen 59. Its molecular function is described by: . It is involved in the biological process described with: . 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.
FBgn0032193	CG5727	0.343848264	0.411126728	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG5727 (FBgn0032193). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:10209853..10210681. It has the cytological map location 31B1. Its molecular function is described by: . The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 12-18 embryonic stages.
FBgn0041171	ago	0.34418397	0.388296802	0.999936032	NA	FBXW7	high	NA	NA	NA	"The gene archipelago is referred to in FlyBase by the symbol Dmel\ago (CG15010, FBgn0041171). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3L:4246343..4254306. It has the cytological map location 64A11-64A12. Protein features are: F-box domain; G-protein beta WD-40 repeat; Six-bladed beta-propeller, TolB-like; WD40 repeat; WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: ubiquitin-protein transferase activity; cyclin binding; protein binding; ubiquitin-specific protease binding. It is involved in the biological process described with 14 unique terms, many of which group under: animal organ development; proteolysis; growth; regulation of primary metabolic process; regulation of multicellular organismal process; cellular biosynthetic process; branching involved in open tracheal system development; negative regulation of gliogenesis; negative regulation of growth; cellular component morphogenesis; regulation of exit from mitosis; cellular protein metabolic process; protein metabolic process. 36 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval dorsal trunk; germline cyst; cellular process; tertiary pigment cell; single-organism cellular process; interommatidial bristle; mechanosensory sensory organ; mitotic cell cycle; ovariole; female organism; cell cycle. The phenotypic classes of alleles include: increased mortality; increased mortality during development; phenotype; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0004629	Cys	0.344254881	0.316842036	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Cystatin-like is referred to in FlyBase by the symbol Dmel\Cys (CG8050, FBgn0004629). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:14569103..14569644. It has the cytological map location 88C6. Protein features are: Cystatin domain; Proteinase inhibitor I25, cystatin, conserved site. Its molecular function is described by: cysteine-type endopeptidase inhibitor activity. It is involved in the biological process described with: multicellular organism reproduction. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of moderately high expression.  Peak expression observed within 06-18 hour embryonic stages.  "
FBgn0039329	CG10669	0.344386995	0.412256918	0.999936032	NA	ZFP62;ZNF658B;ZNF628;ZNF485;ZNF721;ZNF648;ZNF493;ZNF808;ZNF845;ZNF681;ZNF226	low;low;low;low;low;low;low;low;low;low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10669 (FBgn0039329). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:25331363..25335243. It has the cytological map location 96D1. Protein features are: Zinc finger C2H2-type; Zinc finger, AD-type. Its molecular function is described by: nucleic acid binding; zinc ion binding. The biological processes in which it is involved are not known. 13 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0023143	Uba1	0.344396547	0.334197688	0.999936032	NA	UBA1;UBA7;UBA6	high;moderate;moderate	NA	NA	NA	"The gene Ubiquitin activating enzyme 1 is referred to in FlyBase by the symbol Dmel\Uba1 (CG1782, FBgn0023143). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:9688289..9693328. It has the cytological map location 46A1. Protein features are: THIF-type NAD/FAD binding fold; Ubiquitin-activating enzyme E1; Ubiquitin-activating enzyme E1, C-terminal; Ubiquitin-activating enzyme E1, Cys active site; Ubiquitin-activating enzyme E1, FCCH domain; Ubiquitin-activating enzyme E1, conserved site; Ubiquitin-activating enzyme E1, four-helix bundle; Ubiquitin-activating enzyme, catalytic cysteine domain; Ubiquitin/SUMO-activating enzyme E1. Its molecular function is described by: ubiquitin activating enzyme activity. It is involved in the biological process described with 15 unique terms, many of which group under: cellular response to stimulus; anatomical structure regression; regulation of growth; macromolecule localization; head development; germ cell development; monosaccharide metabolic process; regulation of signal transduction; localization; regulation of small GTPase mediated signal transduction; cell proliferation; regulation of cell death; neuron remodeling; single organism reproductive process. 48 alleles are reported. The phenotypes of these alleles manifest in: somatic precursor cell; embryo; dendrite; humeral disc; acellular anatomical structure; somatic stem cell; dopaminergic neuron; somatodendritic compartment; wing vein; sensory neuron. The phenotypic classes of alleles include: increased mortality; phenotype; increased mortality during development; lethal - all die before end of P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.  "
FBgn0264089	sli	0.344511788	0.402330612	0.999936032	NA	SLIT2;SLIT3;SLIT1	high;moderate;moderate	NA	transmembrane protein	NA	"The gene slit is referred to in FlyBase by the symbol Dmel\sli (CG43758, FBgn0264089). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (4 unique). Gene sequence location is 2R:15869495..15922118. It has the cytological map location 52C9-52D2. Protein features are: Concanavalin A-like lectin/glucanase domain; Cysteine-rich flanking region, C-terminal; Cystine knot, C-terminal; EGF-like calcium-binding domain; EGF-like calcium-binding, conserved site; EGF-like domain; EGF-like, conserved site; EGF-type aspartate/asparagine hydroxylation site; Growth factor receptor cysteine-rich domain; Laminin G domain; Leucine-rich repeat; Leucine-rich repeat N-terminal domain; Leucine-rich repeat domain, L domain-like; Leucine-rich repeat, typical subtype. Its molecular function is described by: Roundabout binding; heparin binding; calcium ion binding. It is involved in the biological process described with 20 unique terms, many of which group under: cell-cell signaling; signal transduction; embryonic organ development; regulation of multicellular organismal development; regulation of cell-cell adhesion; regulation of chemotaxis; cell-cell adhesion; development of primary sexual characteristics; formation of primary germ layer; outflow tract morphogenesis; regulation of response to external stimulus. 66 alleles are reported. The phenotypes of these alleles manifest in: eo-type sensillum; eo support cell; salivary gland; somatodendritic compartment; ganglionic branch primordium; abdominal 5 lateral VUM motor neuron; pericardial cell; dorsal neurohemal organ; abdominal 7 ventral VUM motor neuron; axon; trunk mesoderm; class IV dendritic arborizing neuron; neuroblast MNB; cardioblast. The phenotypic classes of alleles include: increased mortality; visible; phenotype; viable; lethal - all die before end of P-stage."
FBgn0039450	CG5484	0.344807676	0.325366965	0.999936032	NA	YIF1B;YIF1A	high;moderate	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG5484 (FBgn0039450). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3R:26717871..26719806. It has the cytological map location 97C5. Protein features are: Yif1 family. Its molecular function is unknown. It is involved in the biological process described with: neuron projection morphogenesis; protein secretion; ER to Golgi vesicle-mediated transport; cell morphogenesis. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die during embryonic stage; lethal - all die during larval stage; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.
FBgn0035141	Cypl	0.34495811	0.356817814	0.999936032	PPIL1	PPIL1	high	NA	NA	NA	"The gene Cyclophilin-like is referred to in FlyBase by the symbol Dmel\Cypl (CG13892, FBgn0035141). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:542122..542931. It has the cytological map location 61C3. Protein features are: Cyclophilin-like domain; Cyclophilin-type peptidyl-prolyl cis-trans isomerase; Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain; Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site. Its molecular function is described by: peptidyl-prolyl cis-trans isomerase activity. It is involved in the biological process described with: mRNA splicing, via spliceosome; protein peptidyl-prolyl isomerization; protein folding. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0052198	CG32198	0.344982356	0.185241664	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG32198 (FBgn0052198). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:18526976..18527445. It has the cytological map location 75D1. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; flight defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the larval period.
FBgn0036226	CG7252	0.345488849	0.410593157	0.999936032	NA	MATN2	low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG7252 (FBgn0036226). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:11947675..11949248. It has the cytological map location 68E3. Protein features are: Chitin binding domain. Its molecular function is described by: chitin binding. It is involved in the biological process described with: chitin metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period.
FBgn0264273	Sema2b	0.345719439	0.325821446	0.999936032	NA	SEMA4C;SEMA4A;SEMA4D;SEMA4G;SEMA6B;SEMA6D;SEMA6A;SEMA6C;SEMA7A;SEMA3F;SEMA3E;SEMA4F;SEMA3D;SEMA3C;SEMA3G;SEMA3A;SEMA4B	high;moderate;moderate;moderate;low;low;low;low;moderate;low;moderate;moderate;moderate;low;moderate;low;moderate	NA	NA	NA	"The gene Semaphorin 2b is referred to in FlyBase by the symbol Dmel\Sema2b (CG33960, FBgn0264273). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 2R:16386524..16431758. It has the cytological map location 53C4. Protein features are: Immunoglobulin-like fold; Sema domain; Semaphorin; WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. It is involved in the biological process described with: olfactory bulb axon guidance; dendrite self-avoidance; synaptic target attraction; dendrite guidance; regulation of cell-matrix adhesion. 21 alleles are reported. The phenotypes of these alleles manifest in: dendrite; adult brain; antennal lobe; class I dendritic arborizing neuron; class IV dendritic arborizing neuron; segmental nerve branch SNa of A1-7; adult olfactory receptor neuron. The phenotypic classes of alleles include: neuroanatomy defective; fertile; viable."
FBgn0004592	Eig71Ee	0.346055601	0.254833819	0.999936032	NA	MUC7	low	NA	NA	NA	"The gene Ecdysone-induced gene 71Ee is referred to in FlyBase by the symbol Dmel\Eig71Ee (CG7604, FBgn0004592). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:15654472..15656010. It has the cytological map location 71E5. Its molecular function is described by: structural molecule activity. It is involved in the biological process described with: puparial adhesion; hemolymph coagulation. 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed during late larval stages.  "
FBgn0032929	Mcm10	0.346055601	0.254833819	0.999936032	NA	MCM10	high	NA	NA	NA	"The gene Minichromosome maintenance 10 is referred to in FlyBase by the symbol Dmel\Mcm10 (CG9241, FBgn0032929). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:21179933..21182812. It has the cytological map location 39B1. Protein features are: Replication factor Mcm10, C-terminal; Zinc finger, Mcm10/DnaG-type. Its molecular function is described by: single-stranded DNA binding; DNA replication origin binding. It is involved in the biological process described with: heterochromatin organization involved in chromatin silencing; female meiosis chromosome segregation; DNA replication; DNA replication initiation; eye-antennal disc development; positive regulation of R7 cell differentiation; chromosome condensation; positive regulation of mitotic cell cycle; negative regulation of compound eye retinal cell apoptotic process; DNA endoreduplication. 19 alleles are reported. The phenotypes of these alleles manifest in: eye disc; nurse cell; condensed nuclear chromosome; ommatidium; eye; embryonic/larval brain; polytene chromosome; photoreceptor cell R7. The phenotypic classes of alleles include: cell death defective; semi-sterile; partially lethal; increased mortality; phenotype; lethal - all die during P-stage; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0264785	Hph	0.346455348	0.310836782	0.999936032	NA	EGLN3;EGLN1;EGLN2	high;moderate;moderate	NA	NA	NA	"The gene HIF prolyl hydroxylase is referred to in FlyBase by the symbol Dmel\Hph (CG44015, FBgn0264785). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 3R:5257037..5269507. It has the cytological map location 82F3-82F8. Protein features are: Oxoglutarate/iron-dependent dioxygenase; Prolyl 4-hydroxylase, alpha subunit; Zinc finger, MYND-type. Its molecular function is described by: L-ascorbic acid binding; iron ion binding; zinc ion binding; peptidyl-proline dioxygenase activity; peptidyl-proline 4-dioxygenase activity. It is involved in the biological process described with 11 unique terms, many of which group under: metabolic process; response to stress; response to decreased oxygen levels; cellular protein modification process; macromolecule localization; organonitrogen compound metabolic process; nitrogen compound metabolic process; cellular response to stimulus; intracellular transport; cellular response to hypoxia; anatomical structure development; positive regulation of biological process; anatomical structure morphogenesis; respiratory system development; primary metabolic process. 41 alleles are reported. The phenotypes of these alleles manifest in: terminal tracheal cell; border follicle cell; embryonic/larval fat body; eye; embryonic/larval tracheal system. The phenotypic classes of alleles include: cell number defective; cell size defective; size defective; increased mortality; fertile; developmental rate defective; viable; phenotype."
FBgn0030011	Gbeta5	0.346590679	0.397076044	0.999936032	GNB5	GNB5	high	NA	NA	NA	"The gene G‘_5 is referred to in FlyBase by the symbol Dmel\G‘_5 (CG10763, FBgn0030011). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:8150731..8152275. It has the cytological map location 7D16. Protein features are: G-protein beta WD-40 repeat; G-protein, beta subunit; Guanine nucleotide-binding protein, beta subunit; WD40 repeat; WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: . It is involved in the biological process described with: G-protein coupled receptor signaling pathway. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 06-24 hour embryonic stages, during early larval stages, during late pupal stages.  "
FBgn0016984	sktl	0.346627654	0.35499917	0.999936032	NA	PIP5K1A;PIP5K1C;PIP5K1B;PIPSL;PIP5KL1	moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"The gene skittles is referred to in FlyBase by the symbol Dmel\sktl (CG9985, FBgn0016984). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:20827282..20836028. It has the cytological map location 57B3. Protein features are: Phosphatidylinositol-4-phosphate 5-kinase; Phosphatidylinositol-4-phosphate 5-kinase, C-terminal; Phosphatidylinositol-4-phosphate 5-kinase, N-terminal domain; Phosphatidylinositol-4-phosphate 5-kinase, core. Its molecular function is described by: protein binding; 1-phosphatidylinositol-4-phosphate 5-kinase activity. It is involved in the biological process described with 13 unique terms, many of which group under: cellular protein localization; lipid metabolic process; animal organ development; regulation of phosphorus metabolic process; cortical actin cytoskeleton organization; establishment of cell polarity; microtubule cytoskeleton organization; glycerophospholipid metabolic process; macromolecule localization; macromolecule modification. 38 alleles are reported. The phenotypes of these alleles manifest in: cell; anatomical group; non-connected developing system; chaeta; dorsal mesothorax; somatic cell of ovary; eo-type sensillum; male germline cyst; vesicle; egg chamber; presumptive embryonic/larval peripheral nervous system; intracellular part; acellular anatomical structure; rhabdomere; cell part. The phenotypic classes of alleles include: lethal; cell cycle defective; increased mortality; cell polarity defective; visible; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0004170	sc	0.346725055	0.352270459	0.999936032	NA	ASCL1;ASCL2	moderate;moderate	DNA-binding with transcription factor activity(HLH)	NA	NA	"The gene scute is referred to in FlyBase by the symbol Dmel\sc (CG3827, FBgn0004170). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:396060..397497. It has the cytological map location 1A8. Protein features are: Achaete-scute transcription factor-related; Myc-type, basic helix-loop-helix (bHLH) domain. Its molecular function is described by: transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding; protein heterodimerization activity; RNA polymerase II regulatory region sequence-specific DNA binding; sequence-specific DNA binding; transcription factor binding; protein binding; transcription factor activity, sequence-specific DNA binding. It is involved in the biological process described with 17 unique terms, many of which group under: animal organ development; reproduction; sex determination; regulation of glucose metabolic process; positive regulation of RNA metabolic process; regulation of carbohydrate metabolic process; sensory organ development; regulation of cell differentiation; apoptotic process; regulation of cell death. 182 alleles are reported. The phenotypes of these alleles manifest in: sensory organ cell; anepisternum; head segment; larval thorax; prepupa; muscle system; sensillum campaniformium of dorsal radius Sc4d; segment of antenna; abdominal sternite bristle; mesothoracic metatarsus; tormogen cell; mesothoracic tarsal bristle longitudinal row 6; proneural cluster; antennal segment. The phenotypic classes of alleles include: sterile; phenotype; fertile; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 00-12 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0039966	Rab21	0.34700669	0.32471668	0.999936032	NA	RAB21	high	NA	NA	NA	"The gene Rab21 is referred to in FlyBase by the symbol Dmel\Rab21 (CG17515, FBgn0039966). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:23012140..23013409. It has the cytological map location 20F3. Protein features are: P-loop containing nucleoside triphosphate hydrolase; Small GTP-binding protein domain; Small GTPase superfamily. Its molecular function is described by: GTPase activity; phosphatidylinositol 3-kinase catalytic subunit binding; GTP binding; protein binding. It is involved in the biological process described with: cortical actin cytoskeleton organization; regulation of endocytosis; positive regulation of autophagosome maturation; vesicle-mediated transport; Rab protein signal transduction. 10 alleles are reported. The phenotypes of these alleles manifest in: autolysosome; fat body; macrophage. The phenotypic classes of alleles include: viable; starvation stress response defective; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0053346	CG33346	0.347010945	0.304569105	0.999936032	NA	ENDOG	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG33346 (FBgn0053346). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:28669233..28670452. It has the cytological map location 98E1. Protein features are: DNA/RNA non-specific endonuclease; DNA/RNA non-specific endonuclease, active site; Extracellular Endonuclease, subunit A. Its molecular function is described by: nucleic acid binding; hydrolase activity; metal ion binding. It is involved in the biological process described with: apoptotic DNA fragmentation. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during early pupal stages.  "
FBgn0034246	Dcr-2	0.347041683	0.376654706	0.999936032	NA	DICER1	moderate	NA	NA	NA	"The gene Dicer-2 is referred to in FlyBase by the symbol Dmel\Dcr-2 (CG6493, FBgn0034246). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:17574979..17581525. It has the cytological map location 54C10. Protein features are: DEAD/DEAH box helicase domain; Dicer dimerisation domain; Double-stranded RNA-binding domain; Helicase superfamily 1/2, ATP-binding domain; Helicase, C-terminal; P-loop containing nucleoside triphosphate hydrolase; PAZ domain; Ribonuclease III domain. Its molecular function is described by: siRNA binding; ATPase activity; helicase activity; protein binding; ATP binding; deoxyribonuclease I activity; ribonuclease III activity; double-stranded RNA binding. It is involved in the biological process described with 16 unique terms, many of which group under: cell death; dosage compensation by hyperactivation of X chromosome; behavior; regulation of immune effector process; single-organism transport; localization; locomotory behavior; regulation of multi-organism process; establishment of RNA localization; apoptotic nuclear changes. 40 alleles are reported. The phenotypes of these alleles manifest in: plasma membrane bounded cell projection; larva; cell junction; spermatocyte; crossvein; embryonic tagma; spermatid; neuron part; cell projection; primary spermatocyte cyst; larval thoracic segment; embryonic/larval peripheral nervous system; intracellular organelle lumen; occluding junction; mitochondrial crista; presynaptic active zone; flight muscle. The phenotypic classes of alleles include: locomotor behavior defective; behavior defective; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.  "
FBgn0023388	Dap160	0.347066062	0.364191856	0.999936032	ITSN1	ITSN2;ITSN1	high;high	NA	NA	NA	"The gene Dynamin associated protein 160 is referred to in FlyBase by the symbol Dmel\Dap160 (CG1099, FBgn0023388). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (all unique). Gene sequence location is 2L:21134439..21142347. It has the cytological map location 39A3-39A4. Protein features are: EF-Hand 1, calcium-binding site; EF-hand domain; EF-hand domain pair; EH domain; RNA recognition motif domain; SH3 domain. Its molecular function is described by: calcium ion binding; nucleic acid binding; protein binding. It is involved in the biological process described with: positive regulation of neuroblast proliferation; synaptic growth at neuromuscular junction; positive regulation of protein kinase activity; protein localization; negative regulation of Notch signaling pathway; synaptic vesicle endocytosis. 28 alleles are reported. The phenotypes of these alleles manifest in: NMJ bouton; eo neuron; macrochaeta; eo sensory structure; bouton. The phenotypic classes of alleles include: phenotype; increased mortality during development; increased mortality; lethal - all die before end of P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0031791	AANATL2	0.347238296	0.286971131	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Arylalkylamine N-acyltransferase-like 2 is referred to in FlyBase by the symbol Dmel\AANATL2 (CG9486, FBgn0031791). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:6255859..6256822. It has the cytological map location 26C1. Protein features are: Acyl-CoA N-acyltransferase; GNAT domain. Its molecular function is described by: aralkylamine N-acetyltransferase activity; acyl-CoA N-acyltransferase activity. It is involved in the biological process described with: nitrogen compound metabolic process. 5 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval fat body; lipid particle. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0022213	Cse1	0.347506611	0.370573707	0.999936032	NA	CSE1L	high	NA	transmembrane protein	NA	"The gene Chromosome segregation 1 is referred to in FlyBase by the symbol Dmel\Cse1 (CG13281, FBgn0022213). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:16821156..16825207. It has the cytological map location 36B1-36B2. Protein features are: Armadillo-like helical; Armadillo-type fold; CAS/CSE, C-terminal; Exportin/Importin, Cse1-like; Importin-beta, N-terminal domain. Its molecular function is described by: Ran GTPase binding; nuclear export signal receptor activity. It is involved in the biological process described with: protein export from nucleus; phagocytosis. 22 alleles are reported. The phenotypes of these alleles manifest in: microchaeta; eo neuron; tormogen cell; macrochaeta; thecogen cell; tergite; egg; embryonic/larval neuroblast; ganglion mother cell. The phenotypic classes of alleles include: increased mortality; female sterile; phenotype; viable; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0022355	Tsf1	0.347808509	0.379877795	0.999936032	NA	MELTF;LTF;TF	moderate;moderate;moderate	NA	NA	NA	"The gene Transferrin 1 is referred to in FlyBase by the symbol Dmel\Tsf1 (CG6186, FBgn0022355). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:18387084..18390344. It has the cytological map location 17A9. Protein features are: Transferrin; Transferrin family, iron binding site; Transferrin-like domain. Its molecular function is unknown. It is involved in the biological process described with: olfactory behavior; response to fungus. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0039694	fig	0.34788616	0.398078637	0.999936032	NA	PPTC7	moderate	NA	NA	NA	"The gene fos intronic gene is referred to in FlyBase by the symbol Dmel\fig (CG7615, FBgn0039694). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:29779273..29780452. It has the cytological map location 99C1. Protein features are: PPM-type phosphatase domain. Its molecular function is described by: phosphoprotein phosphatase activity; protein serine/threonine phosphatase activity. It is involved in the biological process described with: protein dephosphorylation; dephosphorylation. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed in adult male stages.  "
FBgn0000636	Fas3	0.348056127	0.339970426	0.999936032	NA	CADM4;CADM1;NECTIN3;PVR	high;high;high;high	NA	transmembrane protein	NA	"The gene Fasciclin 3 is referred to in FlyBase by the symbol Dmel\Fas3 (CG5803, FBgn0000636). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (5 unique). Gene sequence location is 2L:18320102..18393441. It has the cytological map location 36F2-36F4. Protein features are: CD80-like, immunoglobulin C2-set; Immunoglobulin-like domain; Immunoglobulin-like fold. Its molecular function is described by: cell adhesion molecule binding; receptor activity; protein homodimerization activity; receptor binding. It is involved in the biological process described with: axonal fasciculation; olfactory learning; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; synaptic target attraction; learning or memory; synaptic target recognition; axon guidance; ovarian follicle cell development; homophilic cell adhesion via plasma membrane adhesion molecules. 54 alleles are reported. The phenotypes of these alleles manifest in: non-connected developing system; acellular anatomical structure; dorsal mesothorax; non-connected functional system; tagmatic subdivision of integument; presumptive embryonic/larval digestive system; nerve; chorion; larval mesothoracic segment; anatomical group; sensory system. The phenotypic classes of alleles include: lethal - all die before end of prepupal stage; phenotype; increased mortality during development; neuroanatomy defective; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 06-18 hour embryonic stages, during late pupal stages.  "
FBgn0266441	CG45071	0.348487122	0.334883124	0.999936032	NA	CTPS1	low	DNA-binding with transcription factor activity	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG45071 (FBgn0266441). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:15105882..15110730. It has the cytological map location 71B4-71B5. Protein features are: BESS motif; MADF domain. Its molecular function is described by: DNA binding. It is involved in the biological process described with: negative regulation of transcription, DNA-templated. 14 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: visible; lethal."
FBgn0051633	CG31633	0.348854697	0.362622975	0.999936032	NA	FBXL4	low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31633 (FBgn0051633). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:6654760..6656321. It has the cytological map location 26F5. Protein features are: Leucine-rich repeat domain, L domain-like. Its molecular function is described by: ubiquitin-protein transferase activity. It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0030343	ATP7	0.349206441	0.361913546	0.999936032	ATP7A	ATP7B;ATP7A	high;moderate	NA	transmembrane protein	NA	"The gene ATP7 is referred to in FlyBase by the symbol Dmel\ATP7 (CG1886, FBgn0030343). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:11855022..11864754. It has the cytological map location 10F1-10F2. Protein features are: HAD-like domain; Heavy metal-associated domain, HMA; Heavy metal-associated domain, copper ion-binding; Heavy-metal-associated, conserved site; P-type ATPase; P-type ATPase,  transmembrane domain; P-type ATPase, A  domain; P-type ATPase, cytoplasmic domain N; P-type ATPase, phosphorylation site; P-type ATPase, subfamily IB. Its molecular function is described by: copper ion binding; nucleotide binding; copper ion transmembrane transporter activity; cation-transporting ATPase activity. It is involved in the biological process described with: cellular copper ion homeostasis; developmental pigmentation; metal ion homeostasis; larval development; copper ion homeostasis; metal ion transport; adult chitin-containing cuticle pigmentation. 24 alleles are reported. The phenotypes of these alleles manifest in: pupa; mechanosensory chaeta; embryonic head; sensory organ cell; pupal central nervous system; adult abdomen; larva; central nervous system; embryonic tagma; trident; chaeta. The phenotypic classes of alleles include: increased mortality; phenotype; visible; size defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, in adult male stages.  "
FBgn0003969	vap	0.349802339	0.381076873	0.999936032	NA	RASA1	high	NA	NA	NA	"The gene vacuolar peduncle is referred to in FlyBase by the symbol Dmel\vap (CG9209, FBgn0003969). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (1 unique). Gene sequence location is X:15999951..16005812. It has the cytological map location 14A5-14A6. Protein features are: C2 domain; PH domain-like; Pleckstrin homology domain; Ras GTPase-activating protein; Ras GTPase-activating protein 1; Ras GTPase-activating protein, conserved site; RasGAP, SH3 domain; Rho GTPase activation protein; SH2 domain; SH3 domain. Its molecular function is described by: GTPase activator activity. It is involved in the biological process described with: regulation of endocytosis; mushroom body development; regulation of growth; positive regulation of GTPase activity; behavioral response to ethanol; negative regulation of Ras protein signal transduction. 30 alleles are reported. The phenotypes of these alleles manifest in: ellipsoid body; optic lobe; adult brain; wing; nodulus. The phenotypic classes of alleles include: short lived; fertile; viable; visible; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0000037	mAChR-A	0.349822993	0.31349134	0.999936032	NA	CHRM1;CHRM5;CHRM3;CHRM4;CHRM2	high;moderate;moderate;moderate;moderate	NA	transmembrane protein	GPCR	"The gene muscarinic Acetylcholine Receptor, A-type is referred to in FlyBase by the symbol Dmel\mAChR-A (CG4356, FBgn0000037). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:24378630..24390294. It has the cytological map location 60C7. Protein features are: G protein-coupled receptor, rhodopsin-like; GPCR, rhodopsin-like, 7TM; Muscarinic acetylcholine receptor family. Its molecular function is described by: G-protein coupled amine receptor activity; G-protein coupled acetylcholine receptor activity. It is involved in the biological process described with: phospholipase C-activating G-protein coupled receptor signaling pathway; adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway; phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway; synaptic transmission, cholinergic; G-protein coupled acetylcholine receptor signaling pathway. 11 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.  "
FBgn0042627	FASN2	0.349822993	0.31349134	0.999936032	NA	FASN	high	NA	NA	NA	"The gene Fatty acid synthase 2 is referred to in FlyBase by the symbol Dmel\FASN2 (CG3524, FBgn0042627). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:3043947..3056143. It has the cytological map location 23C5. Protein features are: Acyl transferase; Acyl transferase/acyl hydrolase/lysophospholipase; Alcohol dehydrogenase, C-terminal; Alpha/Beta hydrolase fold; Beta-ketoacyl synthase, C-terminal; Beta-ketoacyl synthase, N-terminal; Beta-ketoacyl synthase, active site; Fatty acid synthase, domain 2; GroES-like; Ketoacyl-synthetase, C-terminal extension; Malonyl-CoA ACP transacylase, ACP-binding; NAD(P)-binding domain; Phosphopantetheine binding ACP domain; Polyketide synthase, acyl transferase domain; Polyketide synthase, beta-ketoacyl synthase domain; Polyketide synthase, dehydratase domain; Polyketide synthase, enoylreductase domain; Polyketide synthase, ketoreductase domain; Polyketide synthase, phosphopantetheine-binding domain; Thioesterase; Thiolase-like. Its molecular function is described by 11 unique terms, many of which group under: catalytic activity; transferase activity; transferase activity, transferring acyl groups other than amino-acyl groups; transferase activity, transferring acyl groups; fatty acid synthase activity; thiolester hydrolase activity; S-acyltransferase activity; hydrolase activity, acting on ester bonds; phosphopantetheine binding; oxidoreductase activity, acting on CH-OH group of donors; oxidoreductase activity. It is involved in the biological process described with: methyl-branched fatty acid biosynthetic process; cuticle hydrocarbon biosynthetic process; oxidation-reduction process; cellular response to sucrose stimulus. 16 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; lethal - all die during pupal stage; viable; lethal - all die before end of pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed in adult male stages.  "
FBgn0262972	CR43283	0.349983045	0.286956285	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR43283 (FBgn0262972). It is a non_protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts. Gene sequence location is 3R:11247631..11256123. It has the cytological map location 86D9. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available.
FBgn0042213	CG18731	0.350063313	0.396571892	0.999936032	NA	C19orf25	low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG18731 (FBgn0042213). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:29725027..29725690. It has the cytological map location 99B9. Protein features are: Uncharacterised protein family UPF0449. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 06-18 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0029664	CG10802	0.350148386	0.352692447	0.999936032	NA	AARSD1;PTGES3L-AARSD1	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10802 (FBgn0029664). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:3482965..3484555. It has the cytological map location 3D4. Protein features are: Alanyl-tRNA synthetase, class IIc, N-terminal; Alanyl-tRNA synthetase, class IIc, core domain; Threonyl/alanyl tRNA synthetase, SAD; Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain; Translation protein, beta-barrel domain. Its molecular function is described by: alanine-tRNA ligase activity; ATP binding; nucleic acid binding. It is involved in the biological process described with: alanyl-tRNA aminoacylation. 2 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; sarcomere; Z disc. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0259978	vlc	0.350824074	0.364596093	0.999936032	NA	DLGAP1;DLGAP3;DLGAP4;DLGAP5;DLGAP2	high;high;high;moderate;moderate	NA	NA	NA	"The gene vulcan is referred to in FlyBase by the symbol Dmel\vlc (CG8390, FBgn0259978). It is a protein_coding_gene from Drosophila melanogaster. It has 8 annotated transcripts and 8 polypeptides (2 unique). Gene sequence location is 2R:5702112..5705439. It has the cytological map location 41F9-41F8. Protein features are: SAPAP family. Its molecular function is unknown. It is involved in the biological process described with: signaling; protein complex assembly. 13 alleles are reported. The phenotypes of these alleles manifest in: leg; metathoracic tarsal segment 2; metathoracic tibia; wing. The phenotypic classes of alleles include: visible; viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0034897	Sesn	0.350869669	0.361401863	0.999936032	NA	SESN3;SESN1;SESN2	high;moderate;moderate	NA	NA	NA	"The gene Sestrin is referred to in FlyBase by the symbol Dmel\Sesn (CG11299, FBgn0034897). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 2R:23713900..23734846. It has the cytological map location 59F6-59F7. Protein features are: AhpD-like; Sestrin. Its molecular function is unknown. It is involved in the biological process described with: negative regulation of cell growth; inter-male aggressive behavior; multicellular organism aging; regulation of response to reactive oxygen species; mitophagy; regulation of reactive oxygen species metabolic process. 13 alleles are reported. The phenotypes of these alleles manifest in: myofibril; wing blade. The phenotypic classes of alleles include: cell growth defective; size defective; behavior defective; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed at stages throughout the pupal period.  "
FBgn0033019	CG10395	0.350913038	0.372458382	0.999936032	NA	INO80B;INO80B-WBP1	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10395 (FBgn0033019). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:5350477..5351972. It has the cytological map location 41E5. Protein features are: INO80 complex subunit B-like conserved region; INO80 complex, subunit Ies2; Zinc finger, HIT-type. Its molecular function is unknown. It is involved in the biological process described with: regulation of transcription, DNA-templated; chromatin remodeling. 4 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: viable; body color defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.  "
FBgn0031450	Hrs	0.351322591	0.337871385	0.999936032	NA	HGS	high	NA	NA	NA	"The gene Hepatocyte growth factor regulated tyrosine kinase substrate is referred to in FlyBase by the symbol Dmel\Hrs (CG2903, FBgn0031450). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:2739986..2743377. It has the cytological map location 23A3. Protein features are: ENTH/VHS; FYVE zinc finger; Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain; Ubiquitin binding protein, Hrs/VPS27; Ubiquitin interacting motif; VHS domain; Zinc finger, FYVE-related; Zinc finger, FYVE/PHD-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: metal ion binding; ubiquitin binding. It is involved in the biological process described with 26 unique terms, many of which group under: macromolecule modification; endosomal transport; sexual reproduction; positive regulation of protein metabolic process; cytosolic transport; endocytosis; RNA metabolic process; organelle organization; regulation of biosynthetic process; regulation of peptide transport; endosome transport via multivesicular body sorting pathway; vesicle-mediated transport between endosomal compartments; regulation of phosphorus metabolic process; cellular response to organic substance. 24 alleles are reported. The phenotypes of these alleles manifest in: eo-type sensillum; germline cyst; larval thoracic segment; glial cell; gamete; extracellular organelle; nucleus; plasma membrane bounded cell projection; gland; mesothoracic bristle. The phenotypic classes of alleles include: increased mortality during development; phenotype; increased mortality; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0002571	Mal-A3	0.351364963	0.296648299	0.999936032	NA	SLC3A1;SLC3A2	moderate;low	NA	NA	NA	"The gene Maltase A3 is referred to in FlyBase by the symbol Dmel\Mal-A3 (CG8695, FBgn0002571). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:8455909..8457892. It has the cytological map location 44D1. Protein features are: Glycoside hydrolase superfamily; Glycosyl hydrolase, family 13, catalytic domain. Its molecular function is described by: catalytic activity. It is involved in the biological process described with: carbohydrate metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0037944	CG6923	0.351508872	0.396352828	0.999936032	NA	RNF111;RNF165;RNF115	high;moderate;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6923 (FBgn0037944). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3R:11744229..11750029. It has the cytological map location 86E17. Protein features are: Zinc finger, RING-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: zinc ion binding; ubiquitin protein ligase activity. It is involved in the biological process described with: proteasome-mediated ubiquitin-dependent protein catabolic process; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; protein polyubiquitination. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die during P-stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0262887	CR43242	0.352326796	0.401885059	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR43242 (FBgn0262887). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2L:23069005..23070724. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0033131	CR12842	0.35239462	0.377433324	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CR12842 (FBgn0033131). It is a pseudogene_attribute from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2R:7039130..7039813. It has the cytological map location 42E5. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult male stages.  "
FBgn0267390	dop	0.352651046	0.368831183	0.999936032	NA	MAST4;MAST1;MAST3;MAST2	high;high;high;moderate	NA	NA	NA	"The gene drop out is referred to in FlyBase by the symbol Dmel\dop (CG6498, FBgn0267390). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:15566013..15576313. It has the cytological map location 71E1. Protein features are: AGC-kinase, C-terminal; Microtubule-associated serine/threonine-protein kinase 2; Microtubule-associated serine/threonine-protein kinase, domain; Microtubule-associated serine/threonine-protein kinase, pre-PK domain; PDZ domain; Protein kinase domain; Protein kinase-like domain; Serine/threonine-protein kinase, active site. Its molecular function is described by: ATP binding; protein kinase activity; protein serine/threonine kinase activity; magnesium ion binding. It is involved in the biological process described with 14 unique terms, many of which group under: cellular localization; organelle organization; wing disc development; cellular protein localization; response to stimulus; ameboidal-type cell migration; regulation of nitrogen compound metabolic process; regulation of catalytic activity; sexual reproduction; cell communication; tube development; regulation of cell size; regulation of gene expression; cellularization. 19 alleles are reported. The phenotypes of these alleles manifest in: membrane; synapse; cell part; embryo; cleavage nucleus; ovary; neuromuscular junction; cell; intracellular non-membrane-bounded organelle; cell projection; female germline cyst; intracellular part. The phenotypic classes of alleles include: lethal; increased mortality during development; phenotype; lethal - all die before end of pupal stage."
FBgn0030529	Clic	0.352677417	0.297480516	0.999936032	NA	CLIC5;CLIC2;CLIC4;CLIC3;CLIC1;CLIC6	high;high;moderate;moderate;moderate;moderate	NA	NA	NA	"The gene Chloride intracellular channel is referred to in FlyBase by the symbol Dmel\Clic (CG10997, FBgn0030529). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:13812971..13822307. It has the cytological map location 12C5-12C6. Protein features are: Glutathione S-transferase, C-terminal-like; Thioredoxin-like fold. Its molecular function is described by: lipid binding; calcium ion binding; chloride channel activity. It is involved in the biological process described with: chloride transport; response to alcohol; negative gravitaxis. 25 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: lethal; fertile; visible; viable; partially lethal - majority die; gravitaxis defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.  "
FBgn0023091	dimm	0.352681897	0.323634363	0.999936032	NA	BHLHA15	high	DNA-binding with transcription factor activity(HLH)	NA	NA	"The gene dimmed is referred to in FlyBase by the symbol Dmel\dimm (CG8667, FBgn0023091). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:21331756..21342155. It has the cytological map location 39D1. Protein features are: Myc-type, basic helix-loop-helix (bHLH) domain. Its molecular function is described by: protein dimerization activity. It is involved in the biological process described with: neuroendocrine cell differentiation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of hormone secretion; regulation of transcription, DNA-templated; ventral cord development; positive regulation of peptide secretion. 14 alleles are reported. The phenotypes of these alleles manifest in: wing; rhabdomere; apterous-expressing neuron of the lateral cluster of the thorax; apterous-expressing neuron of the lateral cluster of the thorax Ap4; eye photoreceptor cell. The phenotypic classes of alleles include: lethal; increased mortality during development; viable; phenotype; neuroanatomy defective; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed within 12-24 hour embryonic stages.  "
FBgn0044511	mRpS21	0.352812949	0.338549977	0.999936032	NA	MRPS21	high	NA	NA	NA	"The gene mitochondrial ribosomal protein S21 is referred to in FlyBase by the symbol Dmel\mRpS21 (CG32854, FBgn0044511). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:13381276..13381809. It has the cytological map location 87E8. Protein features are: Ribosomal protein S21. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation; translation. 7 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 06-12 hour embryonic stages, during early larval stages, during late pupal stages, in adult female stages.  "
FBgn0011829	Ret	0.353096483	0.348277455	0.999936032	NA	RET;FGFR4;FGFR1;FGFR3;FGFR2	high;low;low;low;low	NA	transmembrane protein	NA	"The gene Ret oncogene is referred to in FlyBase by the symbol Dmel\Ret (CG14396, FBgn0011829). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:21182446..21198762. It has the cytological map location 39B1. Protein features are: Protein kinase domain; Protein kinase, ATP binding site; Protein kinase-like domain; Serine-threonine/tyrosine-protein kinase, catalytic domain; Tyrosine-protein kinase, active site; Tyrosine-protein kinase, catalytic domain. Its molecular function is described by: protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase activity; calcium ion binding; ATP binding; integrin binding. It is involved in the biological process described with: positive regulation of cell-matrix adhesion; actin filament organization; protein phosphorylation; dendrite development; signal transduction. 26 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; multidendritic neuron; dorsal mesothorax; abdominal segment; trichogen cell; neuron; genital arch; muscle system; somatic muscle; terminalia; larval thorax. The phenotypic classes of alleles include: increased mortality during development; phenotype; increased cell size; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0036747	CG6052	0.35313411	0.272552781	0.999936032	NA	ABCA3;ABCA5;ABCA10;ABCA6;ABCA8;ABCA9;ABCA12;ABCA2;ABCA4;ABCA13;ABCA1;ABCA7	moderate;moderate;moderate;moderate;moderate;moderate;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6052 (FBgn0036747). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:17723718..17729244. It has the cytological map location 74F3. Protein features are: AAA+ ATPase domain; ABC transporter A, ABCA; ABC transporter, conserved site; ABC transporter-like; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: ATP binding; ATPase activity, coupled to transmembrane movement of substances. It is involved in the biological process described with: lipid transport; transport. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very low expression to a trough of no expression detected.  Peak expression observed during late larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0261508	CG42656	0.353796439	0.399513605	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG42656 (FBgn0261508). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:7492961..7493271. It has the cytological map location 84D9. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, in adult male stages.  "
FBgn0036202	CG6024	0.35386294	0.30069995	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6024 (FBgn0036202). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:11733589..11766182. It has the cytological map location 68D3-68D4. Protein features are: CUB domain; Low-density lipoprotein (LDL) receptor class A repeat; Low-density lipoprotein (LDL) receptor class A, conserved site. Its molecular function is unknown. The biological processes in which it is involved are not known. 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-18 embryonic stages.  "
FBgn0029937	CG8300	0.354184928	0.339521907	0.999936032	NA	FAM177A1;FAM177B	high;moderate	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG8300 (FBgn0029937). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:7104885..7106345. It has the cytological map location 6F5. Protein features are: FAM177 family. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed at stages throughout the pupal period.
FBgn0032189	Ripalpha	0.354445953	0.390701044	0.999936032	NA	RPAIN	high	NA	NA	NA	"The gene RPA-interacting protein ‘± is referred to in FlyBase by the symbol Dmel\Rip‘± (CG18145, FBgn0032189). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:10199401..10200974. It has the cytological map location 31B1. Protein features are: RPA-interacting protein; RPA-interacting protein, C-terminal domain. Its molecular function is described by: . The biological processes in which it is involved are not known. 8 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0002901	mus304	0.354807664	0.386982495	0.999936032	NA	ATRIP	high	NA	NA	NA	"The gene mutagen-sensitive 304 is referred to in FlyBase by the symbol Dmel\mus304 (CG7347, FBgn0002901). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:18109814..18112847. It has the cytological map location 75B9-75B10. Protein features are: ATR-interacting protein. Its molecular function is unknown. It is involved in the biological process described with 12 unique terms, many of which group under: single-multicellular organism process; mitotic G2 DNA damage checkpoint; response to radiation; response to abiotic stimulus; nuclear chromosome segregation; epithelium development; meiosis I; homeostatic process; system development; reciprocal meiotic recombination. 16 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; mitotic cell cycle; macrochaeta; wing disc; nucleus; mitotic domain 1; embryo. The phenotypic classes of alleles include: cell cycle defective; viable; phenotype; cell death defective; chemical sensitive; wild-type. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0032848	nesd	0.354807664	0.386982495	0.999936032	NA	SHCBP1;SHCBP1L	high;moderate	NA	NA	NA	"The gene nessun dorma is referred to in FlyBase by the symbol Dmel\nesd (CG10722, FBgn0032848). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:20093972..20096253. It has the cytological map location 38B6. Protein features are: Pectin lyase fold; Pectin lyase fold/virulence factor. Its molecular function is described by: carbohydrate binding. It is involved in the biological process described with: male meiosis cytokinesis; female germline ring canal stabilization. 13 alleles are reported. The phenotypes of these alleles manifest in: nurse cell ring canal; spermatocyte ring canal; cleavage furrow; contractile ring; nurse cell; onion stage spermatid; Nebenkern. The phenotypic classes of alleles include: viable; meiotic cell cycle defective; fertile; male semi-sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-12 hour embryonic stages, during early pupal stages.  "
FBgn0052572	CG32572	0.355132092	0.331923689	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG32572 (FBgn0052572). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:16721183..16726948. It has the cytological map location 15A3. Its molecular function is unknown. It is involved in the biological process described with: mushroom body development; inter-male aggressive behavior. 14 alleles are reported. The phenotypes of these alleles manifest in: mushroom body alpha-lobe; adult mushroom body alpha'-lobe; adult mushroom body beta'-lobe; mushroom body beta-lobe. The phenotypic classes of alleles include: behavior defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed in adult male stages.
FBgn0263050	CG43345	0.355345296	0.383343821	0.999936032	NA	PLD3;PLD5;PLD4	moderate;high;high	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG43345 (FBgn0263050). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:21166046..21168581. It has the cytological map location 39A7. Protein features are: PLD-like domain; Phospholipase D/Transphosphatidylase. Its molecular function is described by: catalytic activity. It is involved in the biological process described with: . 7 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval hemocyte. No phenotypic class data is available.
FBgn0264618	CR43958	0.355368382	0.391618172	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR43958 (FBgn0264618). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 4:557025..557854. It has the cytological map location 102C5. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0041164	armi	0.355411208	0.391782069	0.999936032	NA	MOV10L1;MOV10	high;moderate	NA	NA	NA	"The gene armitage is referred to in FlyBase by the symbol Dmel\armi (CG11513, FBgn0041164). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:3461317..3466303. It has the cytological map location 63E1. Protein features are: P-loop containing nucleoside triphosphate hydrolase; Probable RNA helicase SDE3. Its molecular function is described by: protein binding; DNA helicase activity. It is involved in the biological process described with: germarium-derived egg chamber formation; oogenesis; RNA interference; long-term memory; pole plasm protein localization; dorsal appendage formation; negative regulation of DNA damage checkpoint; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; microtubule organizing center organization; embryonic axis specification. 29 alleles are reported. The phenotypes of these alleles manifest in: dorsal appendage; oocyte; egg chamber; egg. The phenotypic classes of alleles include: sterile; lethal - all die before end of pupal stage; female sterile; memory defective; flightless; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0004957	por	0.355496883	0.37763333	0.999936032	NA	PORCN	high	NA	transmembrane protein	NA	"The gene porcupine is referred to in FlyBase by the symbol Dmel\por (CG6205, FBgn0004957). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is X:18377521..18379854. It has the cytological map location 17A8. Protein features are: Membrane bound O-acyl transferase, MBOAT. Its molecular function is described by: palmitoyltransferase activity; palmitoleoyltransferase activity; Wnt-protein binding. It is involved in the biological process described with: protein secretion; Wnt signaling pathway; regulation of Wnt signaling pathway; protein localization; protein N-linked glycosylation via asparagine; protein lipidation; protein palmitoleylation; Wnt protein secretion; protein palmitoylation. 14 alleles are reported. The phenotypes of these alleles manifest in: sclerite; trichogen cell; non-connected developing system; abdominal 3 ventral denticle belt; presumptive embryonic/larval central nervous system; mechanosensory sensory organ; embryonic/larval dorsal trunk; sensillum; prothoracic segment; epithelium; adult procephalic segment. The phenotypic classes of alleles include: some die during larval stage; segment polarity phenotype; lethal; increased mortality during development; phenotype; lethal - all die before end of prepupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0023523	Or2a	0.355690364	0.257809307	0.999936032	NA	NA	NA	NA	transmembrane protein	GPCR	"The gene Odorant receptor 2a is referred to in FlyBase by the symbol Dmel\Or2a (CG3206, FBgn0023523). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:2246231..2247567. It has the cytological map location 2F2. Protein features are: Olfactory receptor, insect. Its molecular function is described by: olfactory receptor activity; odorant binding; transmembrane signaling receptor activity. It is involved in the biological process described with: sensory perception of smell; detection of chemical stimulus involved in sensory perception of smell. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; smell perception defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very low expression to a trough of extremely low expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0026089	CG14817	0.355806557	0.320172702	0.999936032	NA	MRPL57	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14817 (FBgn0026089). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:1876294..1877270. It has the cytological map location 2B13-2B14. Protein features are: Ribosomal protein 63, mitochondrial. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; lethal - all die during P-stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0036374	Spt20	0.356288543	0.388466878	0.999936032	NA	SUPT20H;SUPT20HL2;SUPT20HL1	high;moderate;moderate	NA	NA	NA	"The gene Spt20 is referred to in FlyBase by the symbol Dmel\Spt20 (CG17689, FBgn0036374). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:13502707..13511541. It has the cytological map location 70B3-70B4. Protein features are: Transcription factor Spt20; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: transcription cofactor activity. It is involved in the biological process described with: histone acetylation. 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, in adult female stages.  "
FBgn0053653	Cadps	0.356324331	0.395696024	0.999936032	NA	CADPS;CADPS2	high;moderate	NA	NA	NA	"The gene Calcium-dependent secretion activator is referred to in FlyBase by the symbol Dmel\Cadps (CG33653, FBgn0053653). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (all unique). Gene sequence location is 4:1230837..1271759. It has the cytological map location 102F8. Protein features are: Calcium-dependent secretion activator; Calcium-dependent secretion activator domain; Munc13 homology 1; PH domain-like; Pleckstrin homology domain. Its molecular function is described by: calcium ion binding. It is involved in the biological process described with: synaptic transmission, glutamatergic; vesicle-mediated transport; neurotransmitter secretion; positive regulation of calcium ion-dependent exocytosis; synaptic vesicle exocytosis; dense core granule exocytosis. 12 alleles are reported. The phenotypes of these alleles manifest in: synaptic vesicle; neuromuscular junction. The phenotypic classes of alleles include: neurophysiology defective; phenotype; viable; hypoactive; locomotor behavior defective; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, during late pupal stages.  "
FBgn0036770	Prestin	0.356739089	0.309159119	0.999936032	SLC26A5	SLC26A5;SLC26A6;SLC26A4;SLC26A3;SLC26A9;SLC26A1;SLC26A2;SLC26A7;SLC26A11;SLC26A8;SLC26A10;MIR6824	high;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene Prestin is referred to in FlyBase by the symbol Dmel\Prestin (CG5485, FBgn0036770). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:17898889..17907812. It has the cytological map location 75A8. Protein features are: SLC26A/SulP transporter; SLC26A/SulP transporter domain; STAS domain. Its molecular function is described by: formate transmembrane transporter activity; inorganic anion exchanger activity; calcium ion transmembrane transporter activity; secondary active sulfate transmembrane transporter activity; sulfate transmembrane transporter activity; oxalate transmembrane transporter activity; chloride channel activity; anion:anion antiporter activity; bicarbonate transmembrane transporter activity. It is involved in the biological process described with: bicarbonate transport; regulation of intracellular pH; oxalate transport; sulfate transport; chloride transmembrane transport; calcium ion transmembrane transport; formate transport; regulation of membrane potential. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0038934	Gld2	0.356743509	0.228656577	0.999936032	NA	PAPD4	moderate	NA	NA	NA	"The gene GLD2 poly(A) polymerase is referred to in FlyBase by the symbol Dmel\Gld2 (CG5732, FBgn0038934). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:22211824..22217415. It has the cytological map location 94A3. Protein features are: PAP/25A-associated. Its molecular function is described by: polynucleotide adenylyltransferase activity; protein binding. It is involved in the biological process described with: RNA polyadenylation; long-term memory. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: memory defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the pupal period, in adult male stages.  "
FBgn0264788	CR44018	0.356743509	0.228656577	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44018 (FBgn0264788). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3R:10639279..10645773. It has the cytological map location 86C3. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0033789	CG13324	0.356786307	0.288127534	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG13324 (FBgn0033789). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:13049146..13049656. It has the cytological map location 49F1. Protein features are: Transcription activator MBF2. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. The phenotypic class of allele includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed during early larval stages.
FBgn0022361	Pur-alpha	0.356889013	0.328166629	0.999936032	NA	PURA;PURB;PURG;MIR4657	high;moderate;moderate;moderate	DNA-binding with transcription factor activity	NA	NA	"The gene Purine-rich binding protein-‘± is referred to in FlyBase by the symbol Dmel\Pur-‘± (CG1507, FBgn0022361). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (4 unique). Gene sequence location is 4:558016..567257. It has the cytological map location 102C5. Protein features are: Purine-rich element binding protein family. Its molecular function is described by: RNA binding; mRNA binding; sequence-specific DNA binding; DNA binding. It is involved in the biological process described with: regulation of chromatin silencing. 21 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 12-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0031052	CG14215	0.357171325	0.394940058	0.999936032	NA	AHCTF1	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG14215 (FBgn0031052). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:19652305..19659407. It has the cytological map location 18D13. Protein features are: ELYS-like domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: chromatin DNA binding. It is involved in the biological process described with: nuclear pore complex assembly. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0034795	MED23	0.357387218	0.394599133	0.999936032	MED23	MED23	high	Co-factor	NA	NA	"The gene Mediator complex subunit 23 is referred to in FlyBase by the symbol Dmel\MED23 (CG3695, FBgn0034795). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:22888928..22894425. It has the cytological map location 59B4. Protein features are: Mediator complex, subunit Med23; Tetratricopeptide-like helical domain. Its molecular function is described by: protein binding; RNA polymerase II transcription cofactor activity. It is involved in the biological process described with: regulation of transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, during early pupal stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0032151	nAChRalpha6	0.357685836	0.2875299	0.999936032	NA	CHRFAM7A;CHRNA7;CHRNA9;CHRND;CHRNB2;CHRNA6;CHRNA2;CHRNB1;CHRNA1;CHRNA4;CHRNA10;CHRNA5;CHRNB3;CHRNG;CHRNE;CHRNA3;CHRNB4	high;moderate;low;low;low;low;low;low;low;low;moderate;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene nicotinic Acetylcholine Receptor ‘±6 is referred to in FlyBase by the symbol Dmel\nAChR‘±6 (CG4128, FBgn0032151). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (6 unique). Gene sequence location is 2L:9793317..9886250. It has the cytological map location 30D1-30E1. Protein features are: Neurotransmitter-gated ion-channel; Neurotransmitter-gated ion-channel ligand-binding domain; Neurotransmitter-gated ion-channel transmembrane domain; Neurotransmitter-gated ion-channel, conserved site; Nicotinic acetylcholine receptor. Its molecular function is described by: acetylcholine-gated cation-selective channel activity. It is involved in the biological process described with: synaptic transmission, cholinergic; response to insecticide; muscle cell cellular homeostasis; cation transport. 37 alleles are reported. The phenotypes of these alleles manifest in: ventral nerve cord; indirect flight muscle. The phenotypic classes of alleles include: neurophysiology defective; viable; lethal; fertile; chemical resistant. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0026570	CG5704	0.358285007	0.317548917	0.999936032	NA	SERHL2;SERHL	moderate;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5704 (FBgn0026570). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:2169553..2170971. It has the cytological map location 62D1. Protein features are: Alpha/Beta hydrolase fold; Alpha/beta hydrolase fold-1. Its molecular function is described by: . It is involved in the biological process described with: . 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0034460	CG18367	0.358356774	0.19271879	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG18367 (FBgn0034460). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:19636660..19637400. It has the cytological map location 56E1. Protein features are: Protein of unknown function DUF4817. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed during late pupal stages.
FBgn0265728	CR44535	0.358356774	0.19271879	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44535 (FBgn0265728). It is a non_protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts. Gene sequence location is 3L:2008722..2010751. It has the cytological map location 62C1. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0015038	Cyp9b1	0.358453884	0.328954969	0.999936032	CYP3A5	CYP3A5;CYP3A43;TBXAS1;CYP3A4;CYP3A7-CYP3A51P;CYP3A7	high;moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"The gene Cytochrome P450-9b1 is referred to in FlyBase by the symbol Dmel\Cyp9b1 (CG4485, FBgn0015038). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:7127838..7129808. It has the cytological map location 42F2. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group IV; Cytochrome P450, conserved site. Its molecular function is described by: heme binding; monooxygenase activity; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0030010	CG10959	0.358601271	0.393555273	0.999936032	NA	ZNF653;ZBTB17;ZBTB48;ZBTB16;HIC1;ZBTB7A;ZBTB38;MTF1;HIC2;BCL6;ZBTB20;ZNF441;ZSCAN10;ZBTB18;ZBTB11;ZNF589;ZBTB7C	low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10959 (FBgn0030010). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:8148783..8150686. It has the cytological map location 7D16. Protein features are: Zinc finger C2H2-type; Zinc finger, double-stranded RNA binding. Its molecular function is described by: nucleic acid binding. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0001233	Hsp83	0.35885851	0.288405037	0.999936032	NA	HSP90AB1;HSP90AA1;HSP90AB3P;HSP90AB2P;HSP90AB4P;HSP90AA4P;HSP90AA5P;HSP90B1	high;moderate;moderate;moderate;moderate;moderate;moderate;low	NA	NA	NA	"The gene Heat shock protein 83 is referred to in FlyBase by the symbol Dmel\Hsp83 (CG1242, FBgn0001233). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:3192969..3197059. It has the cytological map location 63B11. Protein features are: Heat shock protein Hsp90 family; Heat shock protein Hsp90, N-terminal; Heat shock protein Hsp90, conserved site; Histidine kinase-like ATPase, C-terminal domain; Ribosomal protein S5 domain 2-type fold. Its molecular function is described by: unfolded protein binding; TPR domain binding; ATP binding. It is involved in the biological process described with 16 unique terms, many of which group under: response to stress; regulation of cellular process; response to heat; protein targeting; organelle organization; regulation of multicellular organismal process; cellular biosynthetic process; male gamete generation; nervous system development; regulation of circadian rhythm; cold acclimation; transposition; organic substance transport; microtubule cytoskeleton organization; protein folding. 59 alleles are reported. The phenotypes of these alleles manifest in: supramolecular fiber; intracellular membrane-bounded organelle; cellular process; gamete; contractile fiber; abdominal segment; single-organism cellular process; spermatozoon; primary spermatocyte; syncytium. The phenotypic classes of alleles include: phenotype; increased mortality during development; lethal - all die before end of prepupal stage; fertile; locomotor behavior defective; female fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very high expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0031977	baf	0.358907559	0.314334332	0.999936032	NA	BANF1;BANF2	high;moderate	NA	NA	NA	"The gene barrier to autointegration factor is referred to in FlyBase by the symbol Dmel\baf (CG7380, FBgn0031977). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:8029462..8030565. It has the cytological map location 28D3. Protein features are: Barrier- to-autointegration factor, BAF. Its molecular function is described by: DNA binding. It is involved in the biological process described with: chromosome condensation; karyosome formation. 12 alleles are reported. The phenotypes of these alleles manifest in: condensed nuclear chromosome; nuclear chromatin; karyosome; oocyte; embryonic/larval central nervous system; nuclear envelope; imaginal disc; central nervous system. The phenotypic classes of alleles include: lethal; female sterile; mitotic cell cycle defective; female fertile; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0029834	CG5937	0.359235894	0.344316783	0.999936032	KIAA1244	ARFGEF3	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5937 (FBgn0029834). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:6040005..6050381. It has the cytological map location 5D2-5D3. Protein features are: Armadillo-type fold; Sec7 domain; Sec7 domain, alpha orthogonal bundle; Sec7, C-terminal. Its molecular function is described by: ARF guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: regulation of ARF protein signal transduction. 6 alleles are reported. The phenotype of these alleles manifest in: chaeta. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages.  "
FBgn0265967	CR44754	0.359235894	0.344316783	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44754 (FBgn0265967). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is X:16901767..16912724. It has the cytological map location 15C1. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available.
FBgn0267611	CR45949	0.359235894	0.344316783	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45949 (FBgn0267611). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2L:9948908..9951122. It has the cytological map location 30F1. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0002948	nod	0.359356389	0.321259058	0.999936032	NA	KIF4A;KIF4B;KIF27;KIF7	moderate;low;low;low	NA	NA	NA	"The gene no distributive disjunction is referred to in FlyBase by the symbol Dmel\nod (CG1763, FBgn0002948). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:11580772..11585750. It has the cytological map location 10C7-10C8. Protein features are: Kinesin motor domain; Kinesin motor domain, conserved site; P-loop containing nucleoside triphosphate hydrolase; RuvA domain 2-like. Its molecular function is described by: ATP-dependent microtubule motor activity, plus-end-directed; microtubule motor activity; ATP binding; microtubule plus-end binding. It is involved in the biological process described with: positive regulation of microtubule polymerization; meiotic chromosome segregation; distributive segregation; microtubule-based movement; female meiotic nuclear division; spindle assembly involved in female meiosis I; establishment of meiotic spindle orientation. 38 alleles are reported. The phenotype of these alleles manifest in: polytene chromosome chromocenter. The phenotypic classes of alleles include: fertile; lethal; viable; mitotic cell cycle defective; meiotic cell cycle defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0037935	CG6834	0.359569269	0.337228687	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6834 (FBgn0037935). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:11684672..11688133. It has the cytological map location 86E15-86E16. Protein features are: CHK kinase-like; Protein kinase-like domain; Protein of unknown function DUF227. Its molecular function is described by: myosin binding. The biological processes in which it is involved are not known. 3 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: some die during pupal stage; lethal - all die during embryonic stage; partially lethal - majority die; visible; lethal; lethal - all die during larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, in adult male stages.  "
FBgn0030805	wus	0.359648614	0.381607742	0.999936032	DNAJC22	DNAJC22	high	NA	transmembrane protein	NA	"The gene wurst is referred to in FlyBase by the symbol Dmel\wus (CG9089, FBgn0030805). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:16938244..16940873. It has the cytological map location 15C4. Protein features are: DnaJ domain; TM2 domain. Its molecular function is unknown. It is involved in the biological process described with: liquid clearance, open tracheal system; endocytosis; regulation of tube length, open tracheal system; extracellular matrix organization. 7 alleles are reported. The phenotypes of these alleles manifest in: presumptive embryonic/larval tracheal system; embryonic/larval tracheal system. The phenotypic classes of alleles include: partially lethal; some die during embryonic stage; lethal - all die during embryonic stage; viable; lethal - all die before end of embryonic stage; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 and 12-18 hour embryonic stages, during late pupal stages.  "
FBgn0036921	RhoGDI	0.360293948	0.291088957	0.999936032	ARHGDIA	ARHGDIA;ARHGDIB;ARHGDIG	high;moderate;moderate	NA	NA	NA	"The gene RhoGDI is referred to in FlyBase by the symbol Dmel\RhoGDI (CG7823, FBgn0036921). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:19928743..19932930. It has the cytological map location 76D5. Protein features are: Immunoglobulin E-set; Rho GDP-dissociation inhibitor domain; Rho protein GDP-dissociation inhibitor. Its molecular function is described by: Rho GDP-dissociation inhibitor activity. The biological processes in which it is involved are not known. 17 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: short lived; lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 06-12 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0046301	CG7148	0.360374229	0.353387787	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7148 (FBgn0046301). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:21830544..21832253. It has the cytological map location 78F4. Protein features are: Leucine-rich repeat domain, L domain-like. Its molecular function is described by: ubiquitin-protein transferase activity. It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, in adult male stages.  "
FBgn0260935	Vps15	0.36070135	0.354686649	0.999936032	NA	PIK3R4	high	NA	NA	NA	"The gene Vacuolar protein sorting 15 is referred to in FlyBase by the symbol Dmel\Vps15 (CG9746, FBgn0260935). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3R:9240757..9245869. It has the cytological map location 85D1-85D2. Protein features are: Armadillo-like helical; Armadillo-type fold; G-protein beta WD-40 repeat; Protein kinase domain; Protein kinase-like domain; Serine/threonine-protein kinase, active site; WD40 repeat; WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: protein serine/threonine kinase activity; ATP binding. It is involved in the biological process described with: cellular response to amino acid starvation; late endosome to vacuole transport; pexophagy; macroautophagy; protein phosphorylation; larval midgut cell programmed cell death; regulation of antimicrobial peptide production; neuron remodeling; protein targeting to vacuole; autophagy. 17 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval midgut; autophagosome; embryonic/larval fat body; gastric caecum; fat body; melanotic mass; gamma Kenyon cell. The phenotypic classes of alleles include: cell death defective; immune response defective; stress response defective; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0038145	Droj2	0.360729864	0.29245317	0.999936032	NA	DNAJA4;DNAJA1;DNAJA2	high;moderate;moderate	NA	NA	NA	"The gene DnaJ-like-2 is referred to in FlyBase by the symbol Dmel\Droj2 (CG8863, FBgn0038145). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is 3R:13382106..13385283. It has the cytological map location 87E8. Protein features are: Chaperone DnaJ; Chaperone DnaJ, C-terminal; DnaJ domain; DnaJ domain, conserved site; HSP40/DnaJ peptide-binding; Heat shock protein DnaJ, cysteine-rich domain. Its molecular function is described by: heat shock protein binding; unfolded protein binding; ATP binding. It is involved in the biological process described with: response to heat; protein folding. 8 alleles are reported. The phenotype of these alleles manifest in: ganglion mother cell. The phenotypic classes of alleles include: lethal; lethal - all die during P-stage; viable; neuroanatomy defective; immune response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0035871	BI-1	0.360800653	0.288948685	0.999936032	TMBIM6	TMBIM6	high	NA	transmembrane protein	NA	"The gene Bax Inhibitor-1 is referred to in FlyBase by the symbol Dmel\BI-1 (CG7188, FBgn0035871). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:8307145..8308941. It has the cytological map location 66C5. Protein features are: Bax inhibitor 1, conserved site; Bax inhibitor 1-related. Its molecular function is described by: endoribonuclease inhibitor activity. It is involved in the biological process described with: salivary gland cell autophagic cell death; negative regulation of endoribonuclease activity; negative regulation of autophagy; negative regulation of apoptotic process; negative regulation of endoplasmic reticulum unfolded protein response; cellular response to starvation; negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response; negative regulation of cell death. 8 alleles are reported. The phenotypes of these alleles manifest in: autophagosome; lysosome; embryonic/larval salivary gland; fat body. The phenotypic classes of alleles include: long lived; viable; starvation stress response defective; fertile; short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed within 06-12 hour embryonic stages, in adult male stages.  "
FBgn0039768	CG15533	0.360816386	0.286433331	0.999936032	NA	SMPD1	moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15533 (FBgn0039768). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:30428820..30431362. It has the cytological map location 99F4. Protein features are: Calcineurin-like phosphoesterase domain, ApaH type; Metallo-dependent phosphatase-like; Saposin B type domain; Sphingomyelin phosphodiesterase. Its molecular function is described by: sphingomyelin phosphodiesterase activity. It is involved in the biological process described with: sphingomyelin catabolic process. 7 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during early larval stages.  "
FBgn0263234	Phae1	0.360967041	0.285610403	0.999936032	NA	PRSS36;PRSS53	low;low	NA	NA	NA	"The gene Phaedra 1 is referred to in FlyBase by the symbol Dmel\Phae1 (CG16996, FBgn0263234). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:12109417..12110664. It has the cytological map location 33C4. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 6 alleles are reported. No phenotypic data is available. No phenotypic class data is available."
FBgn0013279	Hsp70Bc	0.360983402	0.299962264	0.999936032	NA	HSPA1A;HSPA1B;HSPA1L;HSPA6;HSPA8;HSPA2;HSPA5	high;moderate;moderate;moderate;low;low;low	NA	NA	NA	"The gene Heat-shock-protein-70Bc is referred to in FlyBase by the symbol Dmel\Hsp70Bc (CG6489, FBgn0013279). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:12509076..12511461. It has the cytological map location 87B14-87B15. Protein features are: Heat shock protein 70 family; Heat shock protein 70, conserved site; Heat shock protein 70kD, C-terminal domain; Heat shock protein 70kD, peptide-binding domain. Its molecular function is unknown. It is involved in the biological process described with: heat shock-mediated polytene chromosome puffing; response to heat; response to hypoxia; response to toxic substance; response to unfolded protein. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: aging defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed at stages throughout the pupal period.  "
FBgn0001218	Hsc70-3	0.361107849	0.286501539	0.999936032	NA	HSPA5;HSPA1L;HSPA8;HSPA2;HSPA1A;HSPA6;HSPA1B	high;low;low;low;low;low;low	NA	NA	NA	"The gene Heat shock 70-kDa protein cognate 3 is referred to in FlyBase by the symbol Dmel\Hsc70-3 (CG4147, FBgn0001218). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is X:11801696..11807117. It has the cytological map location 10E3-10E4. Protein features are: Heat shock protein 70 family; Heat shock protein 70, conserved site; Heat shock protein 70kD, C-terminal domain; Heat shock protein 70kD, peptide-binding domain. Its molecular function is unknown. It is involved in the biological process described with: response to endoplasmic reticulum stress; regulation of glucose metabolic process; sleep; RNA interference; intestinal stem cell homeostasis. 44 alleles are reported. The phenotypes of these alleles manifest in: larva; ommatidium; rhabdomere R7; pupa; eye; adult antennal lobe projection neuron. The phenotypic classes of alleles include: some die during larval stage; increased mortality; viable; increased mortality during development; lethal - all die during P-stage; phenotype; lethal - all die before end of first instar larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0015609	CadN	0.36117157	0.274019603	0.999936032	NA	CDH23;FAT3;FAT4;FAT1;DCHS2;DCHS1;FAT2	high;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene Cadherin-N is referred to in FlyBase by the symbol Dmel\CadN (CG7100, FBgn0015609). It is a protein_coding_gene from Drosophila melanogaster. It has 12 annotated transcripts and 12 polypeptides (all unique). Gene sequence location is 2L:17647053..17778340. It has the cytological map location 36D2. Protein features are: Cadherin; Cadherin conserved site; Cadherin, cytoplasmic domain; Cadherin-like; Catenin binding domain; Concanavalin A-like lectin/glucanase domain; EGF-like calcium-binding domain; EGF-like domain; EGF-like, conserved site; EGF-type aspartate/asparagine hydroxylation site; Growth factor receptor cysteine-rich domain; Immunoglobulin-like fold; Laminin G domain. Its molecular function is described by: cell adhesion molecule binding; beta-catenin binding; protein homodimerization activity; calcium ion binding; cadherin binding; receptor activity; protein binding. It is involved in the biological process described with 15 unique terms, many of which group under: cell adhesion; cell-cell adhesion; establishment or maintenance of cell polarity; R7 cell differentiation; axonal fasciculation; regulation of axon extension; homophilic cell adhesion via plasma membrane adhesion molecules; biological adhesion; regulation of biological quality; cell-cell adhesion via plasma-membrane adhesion molecules; single organismal cell-cell adhesion. 54 alleles are reported. The phenotypes of these alleles manifest in: medullary intrinsic neuron Mi1; gland; olfactory system; embryonic fiber tract; inner medulla; midline crossing tract; embryonic nervous system of thorax; photoreceptor cell R7; connective; integumentary system; anterior commissure; imaginal disc; olfactory receptor neuron. The phenotypic classes of alleles include: locomotor behavior defective; behavior defective; phenotype; lethal - all die before end of prepupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the pupal period.  "
FBgn0039098	GILT3	0.36119111	0.389716457	0.999936032	NA	IFI30	moderate	NA	NA	NA	"The gene Gamma-interferon-inducible lysosomal thiol reductase 3 is referred to in FlyBase by the symbol Dmel\GILT3 (CG13822, FBgn0039098). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:23677358..23678421. It has the cytological map location 95A7. Protein features are: Gamma interferon inducible lysosomal thiol reductase GILT. Its molecular function is described by: disulfide oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. 3 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: body color defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0052533	CG32533	0.361255588	0.378387262	0.999936032	NA	DHX34	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32533 (FBgn0052533). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:19474156..19479411. It has the cytological map location 18C7. Protein features are: Domain of unknown function DUF1605; Helicase superfamily 1/2, ATP-binding domain; Helicase, C-terminal; Helicase-associated domain; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: ATP-dependent RNA helicase activity; RNA binding; helicase activity. It is involved in the biological process described with: RNA processing. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, during early pupal stages, in adult female stages.  "
FBgn0031227	CG3709	0.361781927	0.377268466	0.999936032	NA	PUS10	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3709 (FBgn0031227). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:153539..155305. It has the cytological map location 21B3. Protein features are: Pseudouridine synthase, catalytic domain. Its molecular function is described by: pseudouridine synthase activity; RNA binding. It is involved in the biological process described with: tRNA pseudouridine synthesis. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die during embryonic stage; viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0033296	Mal-A7	0.361908012	0.283935404	0.999936032	NA	SLC3A1;SLC3A2	moderate;moderate	NA	NA	NA	"The gene Maltase A7 is referred to in FlyBase by the symbol Dmel\Mal-A7 (CG11669, FBgn0033296). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:8468646..8471663. It has the cytological map location 44D1. Protein features are: Glycoside hydrolase superfamily; Glycosyl hydrolase, family 13, catalytic domain. Its molecular function is described by: catalytic activity. It is involved in the biological process described with: carbohydrate metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed in adults stages of both sexes.  "
FBgn0267661	CR45999	0.362041213	0.342760632	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45999 (FBgn0267661). It is a non_protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts. Gene sequence location is 3R:4395549..4397548. It has the cytological map location 82A5. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0015589	Apc	0.362069739	0.367574072	0.999936032	NA	APC2;APC	high;high	NA	NA	NA	"The gene APC-like is referred to in FlyBase by the symbol Dmel\Apc (CG1451, FBgn0015589). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:28832301..28844748. It has the cytological map location 98E5-98E6. Protein features are: Adenomatous polyposis coli (APC)  family; Adenomatous polyposis coli protein repeat; Adenomatous polyposis coli protein, 15 residue repeat; Armadillo; Armadillo-like helical; Armadillo-type fold. Its molecular function is described by: protein binding; beta-catenin binding; microtubule binding. It is involved in the biological process described with 13 unique terms, many of which group under: negative regulation of cell communication; negative regulation of signal transduction; nitrogen compound transport; neurogenesis; imaginal disc development; instar larval development; multi-organism process; regulation of multicellular organismal process; establishment or maintenance of microtubule cytoskeleton polarity; proteolysis. 17 alleles are reported. The phenotypes of these alleles manifest in: somatic precursor cell; somatic cell of testis; somatic stem cell; male germline stem cell; germline cell; germinal proliferation center hub; testis; intestinal stem cell; enteroblast; epithelium. The phenotypic classes of alleles include: viable; increased mortality during development; phenotype; cell lethal; cell death defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 and 12-18 hour embryonic stages, at stages throughout the pupal period.  "
FBgn0032340	Ge-1	0.362069739	0.367574072	0.999936032	NA	EDC4	high	NA	NA	NA	NA
FBgn0004655	wapl	0.362464405	0.365286468	0.999936032	NA	WAPL	high	NA	NA	NA	"The gene wings apart-like is referred to in FlyBase by the symbol Dmel\wapl (CG3707, FBgn0004655). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:2149936..2158983. It has the cytological map location 2D4-2D5. Protein features are: Armadillo-like helical; Armadillo-type fold; WAPL domain; Wings apart-like protein. Its molecular function is described by: . It is involved in the biological process described with: regulation of chromosome condensation; regulation of cohesin loading; chromatin organization; mitotic sister chromatid cohesion; mitotic cohesin unloading; female meiosis chromosome segregation; sister chromatid cohesion. 46 alleles are reported. The phenotypes of these alleles manifest in: eye; heterochromatin; sex comb; tergite; embryo; sternopleural bristle; wing; male genitalia; wing vein; adult abdomen. The phenotypic classes of alleles include: modifier of variegation; lethal; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0039928	Cals	0.362582192	0.313527811	0.999936032	CLSTN2	CLSTN2;CLSTN1;CLSTN3	high;moderate;moderate	NA	transmembrane protein	NA	"The gene Calsyntenin-1 is referred to in FlyBase by the symbol Dmel\Cals (CG11059, FBgn0039928). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 4:1112874..1123357. It has the cytological map location 102F8. Protein features are: Cadherin; Cadherin-like; Calsyntenin; Concanavalin A-like lectin/glucanase domain. Its molecular function is described by: calcium ion binding. It is involved in the biological process described with: calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; homophilic cell adhesion via plasma membrane adhesion molecules; cell-cell adhesion mediated by cadherin. 11 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: short lived; fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 06-18 hour embryonic stages, during late pupal stages.  "
FBgn0028980	tant	0.362587626	0.381874163	0.999936032	NA	NA	NA	NA	NA	NA	"The gene tantalus is referred to in FlyBase by the symbol Dmel\tant (CG6586, FBgn0028980). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:6055136..6057002. It has the cytological map location 65A4. Protein features are: Tantalus-like. Its molecular function is unknown. It is involved in the biological process described with: sensory organ development. 10 alleles are reported. The phenotypes of these alleles manifest in: segment of leg; prothoracic metatarsus; adult thoracic sensillum; sternite; row; acellular anatomical structure; wing vein; adult abdomen; adult external mesothorax; interocellar bristle. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; some die during pupal stage; partially lethal - majority die; visible; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0054039	CG34039	0.362717727	0.384515733	0.999936032	NA	COMMD4	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG34039 (FBgn0054039). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:14560000..14562613. It has the cytological map location 70E2. Protein features are: COMM domain. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0003357	Jon99Ciii	0.363150762	0.281343784	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Jonah 99Ciii is referred to in FlyBase by the symbol Dmel\Jon99Ciii (CG31362, FBgn0003357). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:29922216..29923455. It has the cytological map location 99C7. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 5 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period.  "
FBgn0261458	capt	0.36315804	0.298753108	0.999936032	NA	CAP1;CAP2	high;moderate	NA	NA	NA	"The gene capulet is referred to in FlyBase by the symbol Dmel\capt (CG33979, FBgn0261458). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:1151678..1158262. It has the cytological map location 21F1. Protein features are: Adenylate cyclase-associated CAP; Adenylate cyclase-associated CAP, C-terminal; Adenylate cyclase-associated CAP, N-terminal; C-CAP/cofactor C-like domain; CAP, conserved site, C-terminal; CARP motif; WH2 domain. Its molecular function is described by: actin binding; adenylate cyclase binding. It is involved in the biological process described with 14 unique terms, many of which group under: regulation of biological quality; multi-organism reproductive process; purine nucleotide biosynthetic process; cellular response to stimulus; imaginal disc pattern formation; cell projection organization; regulation of cellular component organization; wing disc pattern formation; rhabdomere development; regulation of purine nucleotide metabolic process; response to external stimulus. 24 alleles are reported. The phenotypes of these alleles manifest in: cell part; plasma membrane bounded cell projection; cell; organ system subdivision; cell projection; eye disc; cytoplasmic part; yolk; supraesophageal ganglion; pupa; ovariole; intracellular. The phenotypic classes of alleles include: increased mortality; phenotype; viable; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-06 hour embryonic stages, during late pupal stages.  "
FBgn0036331	CG14117	0.363199452	0.381574644	0.999936032	NA	NA	NA	DNA-binding with transcription factor activity	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14117 (FBgn0036331). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:13008285..13009450. It has the cytological map location 69F5. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0053977	CG33977	0.363314764	0.33249763	0.999936032	NA	DPM3	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG33977 (FBgn0053977). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:13402559..13403051. It has the cytological map location 87E9-87E10. Protein features are: Dolichol-phosphate mannosyltransferase subunit 3. Its molecular function is described by: dolichyl-phosphate beta-D-mannosyltransferase activity. It is involved in the biological process described with: GPI anchor biosynthetic process; protein O-linked mannosylation. No alleles are reported. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 06-18 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period.  "
FBgn0264501	CR43900	0.363432635	0.335180695	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR43900 (FBgn0264501). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2R:12259409..12260813. It has the cytological map location 48F1. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0037619	CG8159	0.363709677	0.36997279	0.999936032	NA	ZNF284;ZNF341;ZNF221;ZNF784;ZNF8;ZNF560;ZNF281	low;low;low;low;low;low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8159 (FBgn0037619). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:8726854..8728370. It has the cytological map location 85A9. Protein features are: Zinc finger C2H2-type; Zinc finger, AD-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: zinc ion binding; DNA binding; transcription factor activity, sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated. 7 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0262955	RpII140	0.363723356	0.326267602	0.999936032	NA	POLR2B	high	NA	NA	NA	"The gene RNA polymerase II 140kD subunit is referred to in FlyBase by the symbol Dmel\RpII140 (CG3180, FBgn0262955). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:14125791..14130111. It has the cytological map location 88A9. Protein features are: DNA-directed RNA polymerase, subunit 2; DNA-directed RNA polymerase, subunit 2, domain 6; RNA polymerase Rpb2, domain 2; RNA polymerase Rpb2, domain 3; RNA polymerase Rpb2, domain 4; RNA polymerase Rpb2, domain 5; RNA polymerase Rpb2, domain 7; RNA polymerase, beta subunit, conserved site; RNA polymerase, beta subunit, protrusion. Its molecular function is described by: RNA polymerase II activity; DNA binding; DNA-directed 5'-3' RNA polymerase activity; ribonucleoside binding. It is involved in the biological process described with: transcription from RNA polymerase II promoter. 68 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; filzkorper; capitellum; embryonic abdominal segment; adult abdominal segment 5; embryonic segment; adult abdominal segment 6; cephalopharyngeal skeleton; mesothoracic tergum. The phenotypic classes of alleles include: increased mortality during development; phenotype; lethal; increased mortality."
FBgn0003301	rut	0.363980261	0.366291297	0.999936032	NA	ADCY1;ADCY3;ADCY8;ADCY6;ADCY4;ADCY2;ADCY5;ADCY7	high;moderate;moderate;low;low;low;low;low	NA	transmembrane protein	NA	"The gene rutabaga is referred to in FlyBase by the symbol Dmel\rut (CG9533, FBgn0003301). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (6 unique). Gene sequence location is X:14787478..14826073. It has the cytological map location 12F4-12F5. Protein features are: Adenylate cyclase; Adenylate cyclase, N-terminal; Adenylate cyclase, conserved domain; Adenylyl cyclase class-3/4/guanylyl cyclase; Adenylyl cyclase class-4/guanylyl cyclase, conserved site; Armadillo-like helical; Nucleotide cyclase; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: calcium- and calmodulin-responsive adenylate cyclase activity; guanylate cyclase activity; adenylate cyclase activity. It is involved in the biological process described with 29 unique terms, many of which group under: response to stress; single organism signaling; multicellular organism reproduction; regulation of cellular process; neuromuscular junction development; response to heat; response to oxygen-containing compound; cell morphogenesis; cGMP biosynthetic process; regulation of response to stimulus. 38 alleles are reported. The phenotypes of these alleles manifest in: synapse; chaeta; segment; muscle cell; neuromuscular junction; varicosity; eo-type sensillum; neuron part; axon; cell; cell projection. The phenotypic classes of alleles include: phenotype; increased mortality during development; behavior defective; sensory perception defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0034326	CG18540	0.363992351	0.171056227	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG18540 (FBgn0034326). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:18299317..18300072. It has the cytological map location 55C2. Protein features are: Protein of unknown function DUF1091. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed in adults stages of both sexes.
FBgn0035495	CG14989	0.364033493	0.296886072	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14989 (FBgn0035495). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3L:4087581..4092706. It has the cytological map location 64A5. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages.  "
FBgn0002673	twe	0.364145854	0.355852877	0.999936032	NA	CDC25A;CDC25B;CDC25C	moderate;high;moderate	NA	NA	NA	"The gene twine is referred to in FlyBase by the symbol Dmel\twe (CG4965, FBgn0002673). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2L:16259414..16261877. It has the cytological map location 35F1. Protein features are: M-phase inducer phosphatase; Rhodanese-like domain. Its molecular function is described by: protein tyrosine/serine/threonine phosphatase activity; protein tyrosine phosphatase activity. It is involved in the biological process described with: positive regulation of cell cycle G2/M phase transition; regulation of syncytial blastoderm mitotic cell cycle; male meiotic nuclear division; protein dephosphorylation; G2/MI transition of meiotic cell cycle; embryonic pattern specification; regulation of meiotic cell cycle; spermatogenesis; meiotic nuclear envelope disassembly. 24 alleles are reported. The phenotypes of these alleles manifest in: eo support cell; non-membrane-bounded organelle; spermatocyte; cell component; oocyte nucleus; cytoplasmic part; cytoskeletal part; embryo; germline cyst; male germline cell; multi-tissue structure; yolk; intracellular organelle part; late embryo. The phenotypic classes of alleles include: mitotic cell cycle defective; phenotype; fertile; cell cycle defective; semi-sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0262608	CG43134	0.364152503	0.313370014	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG43134 (FBgn0262608). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:4247313..4247785. It has the cytological map location 4B4. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported.
FBgn0085391	trv	0.364274705	0.260131834	0.999936032	NA	TIA1;TIAL1	moderate;moderate	NA	NA	NA	"The gene trivet is referred to in FlyBase by the symbol Dmel\trv (CG34362, FBgn0085391). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (all unique). Gene sequence location is 3R:28026615..28090740. It has the cytological map location 98B7. Protein features are: RNA recognition motif domain. Its molecular function is described by: nucleic acid binding. It is involved in the biological process described with: positive regulation of dendrite morphogenesis; detection of temperature stimulus involved in sensory perception of pain; regulation of alternative mRNA splicing, via spliceosome. 10 alleles are reported. The phenotypes of these alleles manifest in: dorsal multidendritic neuron ddaC; dendrite. The phenotypic classes of alleles include: viable; fertile; heat stress response defective; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages.  "
FBgn0031909	CG5181	0.364285509	0.329908065	0.999936032	NA	NABP2;NABP1	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5181 (FBgn0031909). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:7408533..7409809. It has the cytological map location 27F3. Protein features are: Nucleic acid-binding, OB-fold; SOSS complex subunit B2. Its molecular function is described by: single-stranded DNA binding. It is involved in the biological process described with: mitotic cell cycle checkpoint; DNA repair. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period.  "
FBgn0264606	Fife	0.364862797	0.287657706	0.999936032	NA	PCLO;RIMS1	high;moderate	NA	NA	NA	"The gene Fife is referred to in FlyBase by the symbol Dmel\Fife (CG43955, FBgn0264606). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 3L:2655415..2711690. It has the cytological map location 62E8. Protein features are: C2 domain; PDZ domain; Zinc finger, FYVE/PHD-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: . It is involved in the biological process described with: positive regulation of neurotransmitter secretion; synaptic vesicle clustering; presynaptic active zone assembly; positive regulation of synaptic vesicle clustering. 20 alleles are reported. The phenotypes of these alleles manifest in: t-bar; presynaptic active zone; synapse; synaptic vesicle; mesothoracic tergum; presynaptic membrane; embryonic/larval neuromuscular junction. The phenotypic classes of alleles include: partially lethal - majority die; behavior defective; increased mortality; viable; phenotype; visible."
FBgn0037718	P58IPK	0.364869588	0.292362399	0.999936032	NA	DNAJC3	high	NA	NA	NA	"The gene P58IPK is referred to in FlyBase by the symbol Dmel\P58IPK (CG8286, FBgn0037718). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:9586942..9589581. It has the cytological map location 85D27. Protein features are: DnaJ domain; Tetratricopeptide repeat; Tetratricopeptide repeat 1; Tetratricopeptide repeat-containing domain; Tetratricopeptide-like helical domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die during embryonic stage; viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages, in stages of adults of both sexes.  "
FBgn0266724	Trs20	0.365119685	0.320803119	0.999936032	NA	TRAPPC2;TRAPPC2B	high;moderate	Maybe TF	NA	NA	"The gene TRAPP subunit 20 is referred to in FlyBase by the symbol Dmel\Trs20 (CG5161, FBgn0266724). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:16131001..16131632. It has the cytological map location 72D9. Protein features are: Longin-like domain; Trafficking protein particle complex subunit 2. Its molecular function is described by: . It is involved in the biological process described with: vesicle-mediated transport; dsRNA transport; smoothened signaling pathway; spermatogenesis; ER to Golgi vesicle-mediated transport. 14 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: phenotype; viable; increased mortality during development; increased mortality."
FBgn0004865	Eip78C	0.365155818	0.340399614	0.999936032	NA	NR1D2;NR1D1;RARA	high;low;moderate	DNA-binding with transcription factor activity(zf-C4)	NA	NA	"The gene Ecdysone-induced protein 78C is referred to in FlyBase by the symbol Dmel\Eip78C (CG18023, FBgn0004865). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3L:21226609..21266503. It has the cytological map location 78C2-78C3. Protein features are: Nuclear hormone receptor; Nuclear hormone receptor, ligand-binding domain; WD40/YVTN repeat-like-containing domain; Zinc finger, NHR/GATA-type; Zinc finger, nuclear hormone receptor-type. Its molecular function is described by: steroid hormone receptor activity; transcription factor activity, sequence-specific DNA binding; zinc ion binding; sequence-specific DNA binding. It is involved in the biological process described with: negative regulation of transcription, DNA-templated; steroid hormone mediated signaling pathway; regulation of glucose metabolic process. 51 alleles are reported. The phenotypes of these alleles manifest in: dorsal appendage; eye; female germline cyst; germarium cap cell; germline stem cell; germarium; wing; ommatidium. The phenotypic classes of alleles include: increased mortality during development; phenotype; fertile; some die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages.  "
FBgn0013686	mt:lrRNA	0.365213846	0.278860628	0.999936032	NA	NA	NA	NA	NA	NA	"The gene mitochondrial large ribosomal RNA is referred to in FlyBase by the symbol Dmel\mt:lrRNA (CR34094, FBgn0013686). It is a rRNA_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is mitochondrion_genome:12734..14058. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: pole cell formation. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, during early pupal stages.  CAVEAT: These RNA-Seq temporal profiles depend upon RNA-Seq reads that are uniquely placed in the genome.  For this reason, genes such as histones, Stellates and many classes of RNA genes that are present in multiple exact or near exact copies in the genome, expression levels may be reported as much lower than their true values."
FBgn0052296	Mrtf	0.365720902	0.347894864	0.999936032	NA	MKL1;MKL2;MYOCD	high;moderate;moderate	DNA-binding with transcription factor activity(RPEL)	NA	NA	"The gene Myocardin-related transcription factor is referred to in FlyBase by the symbol Dmel\Mrtf (CG32296, FBgn0052296). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:2717615..2766536. It has the cytological map location 62F2-62F3. Protein features are: RPEL repeat; SAP domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding; activating transcription factor binding; RNA polymerase II transcription coactivator activity. It is involved in the biological process described with: cellular response to hypoxia; border follicle cell migration; actin cytoskeleton organization; regulation of cell division; mesodermal cell migration; imaginal disc-derived wing morphogenesis; positive regulation of transcription from RNA polymerase II promoter; open tracheal system development. 30 alleles are reported. The phenotypes of these alleles manifest in: cuticular specialization; late embryo; female reproductive system; somatic precursor cell; central body; trunk mesoderm derivative; somatic muscle; sense organ; ganglionic branch primordium; head; somatic cell of ovary; germ layer derivative; mesoderm. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; lethal; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 and 12-18 hour embryonic stages.  "
FBgn0004049	yrt	0.365745631	0.351354841	0.999936032	NA	EPB41L5;EPB41L4B	high;moderate	NA	NA	NA	"The gene yurt is referred to in FlyBase by the symbol Dmel\yrt (CG9764, FBgn0004049). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 3R:13428867..13434984. It has the cytological map location 87E11. Protein features are: Band 4.1 domain; Ezrin/radixin/moesin-like; FERM adjacent (FA); FERM central domain; FERM conserved site; FERM domain; FERM, C-terminal PH-like domain; FERM, N-terminal; FERM/acyl-CoA-binding protein, 3-helical bundle; PH domain-like; Ubiquitin-related domain. Its molecular function is described by: cytoskeletal protein binding; structural constituent of cytoskeleton. It is involved in the biological process described with: dorsal closure; eye photoreceptor cell development; amnioserosa maintenance; head involution; actomyosin structure organization; germ-band shortening; establishment or maintenance of apical/basal cell polarity; establishment of epithelial cell apical/basal polarity. 30 alleles are reported. The phenotypes of these alleles manifest in: optic lobe neuron; dorsal closure embryo; macrochaeta; adherens junction; cell part; cell junction; sensory system neuron; squamous epithelium; embryonic/first instar larval cuticle; cytoplasmic part. The phenotypic classes of alleles include: lethal - all die before end of P-stage; phenotype; increased mortality during development; lethal - all die before end of prepupal stage; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period, in adult female stages.  "
FBgn0035498	Fit1	0.366052052	0.303928974	0.999936032	NA	FERMT2;FERMT1;FERMT3	high;moderate;moderate	NA	NA	NA	"The gene Fermitin 1 is referred to in FlyBase by the symbol Dmel\Fit1 (CG14991, FBgn0035498). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:4103564..4107116. It has the cytological map location 64A6. Protein features are: Band 4.1 domain; FERM central domain; FERM/acyl-CoA-binding protein, 3-helical bundle; PH domain-like; Pleckstrin homology domain. Its molecular function is described by: cell adhesion molecule binding. It is involved in the biological process described with: cell-matrix adhesion; defense response to Gram-negative bacterium; cardiac muscle tissue development. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during larval stage; some die during pupal stage; lethal - all die before end of pupal stage; lethal - all die during P-stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages.  "
FBgn0053547	Rim	0.366299651	0.380479493	0.999936032	NA	RIMS2;RIMS1;RIMS3;RIMS4	high;moderate;moderate;moderate	NA	NA	NA	"The gene Rab3 interacting molecule is referred to in FlyBase by the symbol Dmel\Rim (CG33547, FBgn0053547). It is a protein_coding_gene from Drosophila melanogaster. It has 14 annotated transcripts and 14 polypeptides (12 unique). Gene sequence location is 3R:17872748..17916578. It has the cytological map location 90C8-90C10. Protein features are: C2 domain; PDZ domain; Rab-binding domain; WD40/YVTN repeat-like-containing domain; Zinc finger, FYVE-related; Zinc finger, FYVE/PHD-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: Rab GTPase binding. It is involved in the biological process described with: synaptic vesicle exocytosis; neuromuscular synaptic transmission; clustering of voltage-gated calcium channels; calcium ion regulated exocytosis; intracellular protein transport; neurotransmitter secretion; vesicle-mediated transport; regulation of synaptic plasticity. 22 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval neuromuscular junction. The phenotypic classes of alleles include: some die during larval stage; developmental rate defective; fertile; neurophysiology defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, in adult male stages.  "
FBgn0026080	Tip60	0.366351832	0.339380528	0.999936032	KAT5	KAT5;KAT8;KAT7	high;moderate;low	Chromatin regulation	NA	NA	"The gene Tat interactive protein 60kDa is referred to in FlyBase by the symbol Dmel\Tip60 (CG6121, FBgn0026080). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:4114800..4117487. It has the cytological map location 4A6-4B1. Protein features are: Acyl-CoA N-acyltransferase; Chromo domain-like; Chromo/chromo shadow domain; Histone acetyltransferase domain, MYST-type; RNA binding activity-knot of a chromodomain. Its molecular function is described by: histone acetyltransferase activity. It is involved in the biological process described with: regulation of transcription, DNA-templated; regulation of gene expression; negative regulation of neuron apoptotic process; nervous system development; regulation of synaptic plasticity; histone acetylation; cellular response to DNA damage stimulus; histone H4 acetylation; histone exchange; regulation of terminal button organization. 16 alleles are reported. The phenotypes of these alleles manifest in: somatic cell; syncytium; type Ib terminal bouton; external sensory organ; mushroom body alpha'-lobe; prepupa; nurse cell; larval thorax; embryonic/larval central nervous system; type I terminal bouton. The phenotypic classes of alleles include: behavior defective; phenotype; increased mortality during development; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during early pupal stages, in adult female stages.  "
FBgn0265873	CR44662	0.366541617	0.376613786	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44662 (FBgn0265873). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is X:15077498..15081255. It has the cytological map location 13A9. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0002564	Lsp1gamma	0.366683817	0.246034668	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Larval serum protein 1 ‘_ is referred to in FlyBase by the symbol Dmel\Lsp1‘_ (CG6821, FBgn0002564). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:66430..68995. It has the cytological map location 61A6. Protein features are: Hemocyanin, C-terminal; Hemocyanin, N-terminal; Hemocyanin/hexamerin; Hemocyanin/hexamerin middle domain; Immunoglobulin E-set; Uncharacterised domain, di-copper centre. Its molecular function is unknown. The biological processes in which it is involved are not known. 11 alleles are reported. The phenotypes of these alleles manifest in: egg; somatic muscle. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the larval period.  "
FBgn0085223	CG34194	0.366809939	0.296045204	0.999936032	NA	SPTSSB;SPTSSA	high;low	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG34194 (FBgn0085223). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:17544190..17545045. It has the cytological map location 54C3. Protein features are: Small subunit of serine palmitoyltransferase-like. Its molecular function is described by: serine C-palmitoyltransferase activity. It is involved in the biological process described with: . No alleles are reported. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages.
FBgn0029903	pod1	0.367185936	0.325665795	0.999936032	NA	CORO7-PAM16;CORO7	high;high	NA	NA	NA	"The gene pod1 is referred to in FlyBase by the symbol Dmel\pod1 (CG4532, FBgn0029903). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (3 unique). Gene sequence location is X:6803684..6813830. It has the cytological map location 6D2-6D3. Protein features are: Anaphase-promoting complex subunit 4, WD40 domain; Coronin; Coronin 7; Domain of unknown function DUF1899; Six-bladed beta-propeller, TolB-like; WD40 repeat; WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: protein binding, bridging; actin binding; microtubule binding; actin filament binding. It is involved in the biological process described with: actin cytoskeleton reorganization; AMPA glutamate receptor clustering; axon guidance. 15 alleles are reported. The phenotypes of these alleles manifest in: intersegmental nerve; longitudinal connective; ventral nerve cord; segmental nerve; commissure. The phenotypic classes of alleles include: fertile; viable; long lived; cell shape defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, during early pupal stages.  "
FBgn0085279	CG34250	0.367443556	0.321249903	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG34250 (FBgn0085279). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:17476222..17477103. It has the cytological map location 74C3. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages.
FBgn0002932	neur	0.367460456	0.33784912	0.999936032	NA	NEURL1B;NEURL1;NEURL3	high;high;moderate	NA	NA	NA	"The gene neuralized is referred to in FlyBase by the symbol Dmel\neur (CG11988, FBgn0002932). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 3R:9020348..9039471. It has the cytological map location 85C2-85C3. Protein features are: Neuralized homology repeat (NHR) domain; Zinc finger, RING-type. Its molecular function is described by: protein binding; zinc ion binding; ubiquitin protein ligase activity; phosphatidylinositol phosphate binding. It is involved in the biological process described with 24 unique terms, many of which group under: behavior; hemocyte differentiation; formation of anatomical boundary; protein modification process; protein localization; cellular component organization; stem cell population maintenance; cell division; appendage morphogenesis; larval lymph gland hemopoiesis; localization; positive regulation of Notch signaling pathway; asymmetric cell division; protein modification by small protein conjugation or removal; cognition; protein complex subunit organization; regulation of anatomical structure morphogenesis; ectoderm development. 115 alleles are reported. The phenotypes of these alleles manifest in: adult labral segment; cell part; exit glial cell; external sensory organ precursor cell IIb; somatic stem cell; compartment boundary; neurosecretory neuron; embryonic/larval lymph gland; eo neuron; tormogen cell; pigment cell; crystal cell; synaptic neuropil subdomain; syncytium; embryonic/larval glial cell; ovariole; plasma membrane bounded cell projection. The phenotypic classes of alleles include: increased mortality; increased mortality during development; phenotype; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0036205	CG14131	0.36788604	0.294603676	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14131 (FBgn0036205). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:11777073..11780485. It has the cytological map location 68D4. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0264291	Det	0.367921535	0.37256827	0.999936032	NA	BIRC5;BIRC7;BIRC3;XIAP;BIRC2;BIRC6;BIRC8	high;low;low;low;low;low;low	NA	NA	NA	"The gene Deterin is referred to in FlyBase by the symbol Dmel\Det (CG12265, FBgn0264291). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:17149667..17150455. It has the cytological map location 90A1-90A2. Protein features are: BIR repeat. Its molecular function is described by: ubiquitin-protein transferase activity; zinc ion binding; cysteine-type endopeptidase inhibitor activity. It is involved in the biological process described with 13 unique terms, many of which group under: mitotic spindle assembly; regulation of molecular function; regulation of signaling; apoptotic process; actomyosin contractile ring assembly; regulation of response to stimulus; cell differentiation; regulation of hydrolase activity; cell-cell signaling; single organism signaling. 22 alleles are reported. The phenotypes of these alleles manifest in: anatomical structure; male organism; ovariole; male reproductive system; organism; intracellular membrane-bounded organelle; intracellular part; female organism; anatomical group; cell. The phenotypic classes of alleles include: lethal - all die during P-stage; phenotype; visible; mitotic cell cycle defective; cell cycle defective."
FBgn0004435	Galphaq	0.368030806	0.314299432	0.999936032	NA	GNAQ;GNA11;GNA14;GNA15;GNAT2;GNAZ;GNAT3	high;moderate;moderate;low;low;low;low	NA	NA	NA	"The gene G protein ‘± q subunit is referred to in FlyBase by the symbol Dmel\G‘±q (CG17759, FBgn0004435). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (3 unique). Gene sequence location is 2R:12612740..12623197. It has the cytological map location 49B8-49B9. Protein features are: G protein alpha subunit, helical insertion; G-protein alpha subunit, group Q; Guanine nucleotide binding protein (G-protein), alpha subunit; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: GTP binding; G-protein beta/gamma-subunit complex binding; G-protein coupled receptor binding; GTPase activity; signal transducer activity. It is involved in the biological process described with 18 unique terms, many of which group under: dopamine receptor signaling pathway; positive regulation of molecular function; thermotaxis; organ or tissue specific immune response; sensory perception; transport; adenylate cyclase-modulating G-protein coupled receptor signaling pathway; regulation of developmental process; cell projection morphogenesis; stabilization of membrane potential; neuron recognition; homeostatic process; mucosal immune response; animal organ development; regulation of phospholipase activity; cellular response to carbon dioxide; sensory perception of smell; modulation of synaptic transmission; localization. 35 alleles are reported. The phenotypes of these alleles manifest in: cell part; pupa; carbon dioxide sensitive neuron; mesothoracic segment; dMP2 neuron; plasma membrane bounded cell projection; cell projection; adult mesothoracic segment; adult olfactory receptor neuron Gr21a/63a; tract neuropil. The phenotypic classes of alleles include: sensory perception defective; wild-type; immune response defective; increased mortality; some die during first instar larval stage; visual behavior defective; phenotype; smell perception defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0016917	Stat92E	0.368504208	0.291277506	0.999936032	NA	STAT5B;STAT5A;STAT6;STAT3;STAT4;STAT2;STAT1	high;moderate;moderate;moderate;moderate;moderate;moderate	DNA-binding with transcription factor activity(STAT_bind)	NA	NA	"The gene Signal-transducer and activator of transcription protein at 92E is referred to in FlyBase by the symbol Dmel\Stat92E (CG4257, FBgn0016917). It is a protein_coding_gene from Drosophila melanogaster. It has 11 annotated transcripts and 11 polypeptides (7 unique). Gene sequence location is 3R:20535323..20552311. It has the cytological map location 92F1. Protein features are: SH2 domain; STAT transcription factor, DNA-binding; STAT transcription factor, DNA-binding, subdomain; STAT transcription factor, all-alpha domain; STAT transcription factor, coiled coil; STAT transcription factor, protein interaction; Transcription factor STAT; p53-like transcription factor, DNA-binding. Its molecular function is described by: signal transducer activity; transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding; DNA binding; transcription factor activity, sequence-specific DNA binding; protein binding. It is involved in the biological process described with 41 unique terms, many of which group under: cell division; open tracheal system development; regulation of immune system process; imaginal disc-derived appendage morphogenesis; cellular response to X-ray; germ-line stem cell population maintenance; nucleobase-containing compound metabolic process; germarium-derived egg chamber formation; cellular response to lipopolysaccharide; compound eye development; regulation of STAT cascade. 73 alleles are reported. The phenotypes of these alleles manifest in: male germline cell; embryonic head; abdominal segment 7; midgut; embryonic/larval hemocoel; tracheal branch primordium; neuron part; pole cell; squamous epithelium; adult external mesothorax; pupal/adult digestive system; adult head sensillum; larval abdominal segment 4; trichogen cell; embryonic abdominal segment 2; ovarian basement membrane. The phenotypic classes of alleles include: visible; mitotic cell cycle defective; phenotype; increased mortality during development; cell death defective; decreased cell number. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.  "
FBgn0265719	CR44526	0.368614124	0.35731879	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44526 (FBgn0265719). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3L:8692703..8693191. It has the cytological map location 66D10. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0036766	CG5506	0.368649567	0.275016002	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5506 (FBgn0036766). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:17883649..17884376. It has the cytological map location 75A8. Protein features are: DM9 repeat; Domain of unknown function DUF3421. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0050083	CG30083	0.368693665	0.274862679	0.999936032	NA	PRSS45;TMPRSS11D;TMPRSS11E;TMPRSS11B;PRSS47;PRSS57;CTSG;GZMB;CMA1;GZMH	low;low;low;low;low;low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG30083 (FBgn0050083). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:15711597..15712644. It has the cytological map location 52C2. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during late larval stages, at stages throughout the pupal period.  "
FBgn0265623	Su(z)2	0.368761071	0.355416639	0.999936032	NA	BMI1;PCGF2;COMMD3-BMI1;PCGF3	moderate;high;moderate;low	DNA-binding with transcription factor activity	NA	NA	"The gene Suppressor of zeste 2 is referred to in FlyBase by the symbol Dmel\Su(z)2 (CG3905, FBgn0265623). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2R:12996501..13007911. It has the cytological map location 49E7. Protein features are: RAWUL domain; WD40/YVTN repeat-like-containing domain; Zinc finger, C3HC4 RING-type; Zinc finger, RING-type; Zinc finger, RING-type, conserved site; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: DNA binding; zinc ion binding; metal ion binding. It is involved in the biological process described with: chromatin silencing; positive regulation of histone methylation. 72 alleles are reported. The phenotypes of these alleles manifest in: arista; macrochaeta; pigment cell; germarium; wing. The phenotypic classes of alleles include: increased mortality; visible; phenotype; increased mortality during development."
FBgn0063499	GstE10	0.369032575	0.378705871	0.999936032	NA	GSTT2B;GSTT1;GSTT2	moderate;moderate;moderate	NA	NA	NA	"The gene Glutathione S transferase E10 is referred to in FlyBase by the symbol Dmel\GstE10 (CG17522, FBgn0063499). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:18396638..18398519. It has the cytological map location 55C6. Protein features are: Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Thioredoxin-like fold. Its molecular function is described by: glutathione transferase activity. It is involved in the biological process described with: glutathione metabolic process. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0032670	CG5783	0.369472251	0.375992761	0.999936032	NA	GLYAT;GLYATL1;GLYATL2;GLYATL3	high;moderate;moderate;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5783 (FBgn0032670). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:18156043..18157162. It has the cytological map location 36E6. Protein features are: Acyl-CoA N-acyltransferase; FR47-like; GNAT domain. Its molecular function is described by: N-acetyltransferase activity. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during late pupal stages, in adult male stages.  "
FBgn0264983	CR44134	0.370002605	0.166777814	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44134 (FBgn0264983). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3R:4436356..4437230. It has the cytological map location 82B1. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0036260	Rh7	0.370083268	0.308233571	0.999936032	NA	OPN4;OPN3;RRH;OPN5	moderate;moderate;moderate;moderate	NA	transmembrane protein	GPCR	"The gene Rhodopsin 7 is referred to in FlyBase by the symbol Dmel\Rh7 (CG5638, FBgn0036260). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:12164205..12175482. It has the cytological map location 68F8-69A1. Protein features are: G protein-coupled receptor, rhodopsin-like; GPCR, rhodopsin-like, 7TM; Opsin; Visual pigments (opsins) retinal binding site. Its molecular function is described by: neuropeptide binding; G-protein coupled photoreceptor activity; G-protein coupled receptor activity. It is involved in the biological process described with: neuropeptide signaling pathway; rhodopsin mediated signaling pathway; cellular response to light stimulus; entrainment of circadian clock by photoperiod; G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; G-protein coupled receptor signaling pathway; visual perception; circadian behavior. 17 alleles are reported. The phenotype of these alleles manifest in: l-LNv neuron. The phenotypic classes of alleles include: photoperiod response variant; circadian rhythm defective; neurophysiology defective; viable; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed in adult male stages.  "
FBgn0050025	CG30025	0.370083268	0.308233571	0.999936032	NA	PRSS36;PRSS53;PRSS45;PRSS8;PRSS27;PRSS22;TPSG1;PRSS33;PRSS38;CMA1;PRSS1;PRSS3	low;low;low;low;low;low;low;low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG30025 (FBgn0050025). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:11353564..11354373. It has the cytological map location 47F4-47F5. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of no expression detected.  Peak expression observed during late larval stages.  "
FBgn0031376	Der-1	0.370433139	0.293651341	0.999936032	NA	DERL1;DERL3;DERL2	high;low;low	NA	NA	NA	NA
FBgn0034529	FAM21	0.370794855	0.375105345	0.999936032	NA	WASHC2A;WASHC2C	high;high	NA	NA	NA	"The gene Family with sequence similarity 21 is referred to in FlyBase by the symbol Dmel\FAM21 (CG16742, FBgn0034529). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:20623547..20628315. It has the cytological map location 57A8. Its molecular function is unknown. It is involved in the biological process described with: positive regulation of cell adhesion. 4 alleles are reported. The phenotype of these alleles manifest in: macrophage. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.  "
FBgn0026148	CG12253	0.37122579	0.375132859	0.999936032	NA	HARBI1	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG12253 (FBgn0026148). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:10987806..10989241. It has the cytological map location 32C1. Protein features are: Harbinger transposase-derived nuclease domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0028920	CG8997	0.371274564	0.271722396	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG8997 (FBgn0028920). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:13843915..13845325. It has the cytological map location 34D7. Protein features are: Haemolymph juvenile hormone binding. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of extremely low expression.  Peak expression observed during late larval stages.
FBgn0036225	CG5883	0.371810375	0.371604945	0.999936032	NA	MATN2	low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5883 (FBgn0036225). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:11943640..11944852. It has the cytological map location 68E3. Protein features are: Chitin binding domain. Its molecular function is described by: chitin binding. It is involved in the biological process described with: chitin metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0259876	Cap-G	0.371810375	0.371604945	0.999936032	NA	NCAPG	high	NA	NA	NA	"The gene Chromosome associated protein G is referred to in FlyBase by the symbol Dmel\Cap-G (CG34438, FBgn0259876). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:13133142..13142820. It has the cytological map location 49E7-49F3. Protein features are: Armadillo-like helical; Armadillo-type fold; Condensin complex subunit 3; Nuclear condensin complex subunit 3, C-terminal domain. Its molecular function is unknown. It is involved in the biological process described with: sister chromatid segregation; mitotic sister chromatid segregation; chromosome condensation; mitotic cytokinesis; epithelium development; synaptonemal complex disassembly; germarium-derived egg chamber formation; mitotic chromosome condensation. 37 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; egg chamber; epithelium; wing; oocyte; embryonic/larval neuroblast; ganglion mother cell. The phenotypic classes of alleles include: mitotic cell cycle defective; phenotype; increased mortality; some die during larval stage; sterile; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0039319	CG13659	0.371882493	0.286399772	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13659 (FBgn0039319). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:25300891..25302317. It has the cytological map location 96D1. Protein features are: CHK kinase-like; Protein kinase-like domain; Protein of unknown function DUF227. Its molecular function is unknown. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0085342	CG34313	0.371920593	0.316121722	0.999936032	NA	SNRNP25	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG34313 (FBgn0085342). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:16879517..16886319. It has the cytological map location 36B3. Its molecular function is described by: . It is involved in the biological process described with: . One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed at stages throughout the larval period, during late pupal stages, in adult male stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0267181	CR45621	0.371932422	0.355785447	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45621 (FBgn0267181). It is a non_protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts. Gene sequence location is X:12612108..12615780. It has the cytological map location 11B3-11B4. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0053276	Urm1	0.371961812	0.372900594	0.999936032	NA	URM1	high	NA	NA	NA	"The gene Ubiquitin-related modifier 1 is referred to in FlyBase by the symbol Dmel\Urm1 (CG33276, FBgn0053276). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:7639811..7640446. It has the cytological map location 66A8. Protein features are: Beta-grasp domain; Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp; Ubiquitin-related modifier 1. Its molecular function is unknown. It is involved in the biological process described with: tRNA thio-modification; negative regulation of JNK cascade. 11 alleles are reported. The phenotype of these alleles manifest in: anterior crossvein. The phenotypic classes of alleles include: increased mortality during development; phenotype; visible; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in adult female stages.  "
FBgn0015396	jumu	0.372149703	0.261797228	0.999936032	NA	FOXN4;FOXN1;FOXR1;FOXR2	high;moderate;moderate;moderate	DNA-binding with transcription factor activity(Fork_head)	NA	NA	"The gene jumeau is referred to in FlyBase by the symbol Dmel\jumu (CG4029, FBgn0015396). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:10350182..10361612. It has the cytological map location 86B1. Protein features are: Fork head domain; Fork head domain conserved site 2; Winged helix-turn-helix DNA-binding domain. Its molecular function is described by: transcription factor activity, sequence-specific DNA binding; transcription regulatory region sequence-specific DNA binding. It is involved in the biological process described with 14 unique terms, many of which group under: cellular component organization; response to stimulus; regulation of nucleic acid-templated transcription; organelle organization; asymmetric protein localization; macromolecule localization; embryonic morphogenesis; defense response to fungus; chromatin organization; organic cyclic compound biosynthetic process; eye development. 53 alleles are reported. The phenotypes of these alleles manifest in: cell; intracellular non-membrane-bounded organelle; embryonic/larval salivary gland; cardial cell; nuclear part; embryonic/larval hemocoel; polytene chromosome; interommatidial bristle; larval thoracic segment; chromosome. The phenotypic classes of alleles include: increased mortality during development; phenotype; modifier of variegation; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0038247	Cad88C	0.372149703	0.261797228	0.999936032	NA	CDHR2;CDH23	high;moderate	NA	transmembrane protein	NA	"The gene Cadherin 88C is referred to in FlyBase by the symbol Dmel\Cad88C (CG3389, FBgn0038247). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:14630478..14641776. It has the cytological map location 88C10. Protein features are: Cadherin; Cadherin conserved site; Cadherin-like. Its molecular function is described by: calcium ion binding. It is involved in the biological process described with: calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; open tracheal system development; cell-cell adhesion mediated by cadherin; homophilic cell adhesion via plasma membrane adhesion molecules. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed during late pupal stages.  "
FBgn0028400	Syt4	0.372151555	0.198290345	0.999936032	NA	SYT4;SYT11;TC2N	high;high;moderate	NA	transmembrane protein	NA	"The gene Synaptotagmin 4 is referred to in FlyBase by the symbol Dmel\Syt4 (CG10047, FBgn0028400). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:7266065..7270809. It has the cytological map location 84D3. Protein features are: C2 domain; Synaptotagmin. Its molecular function is described by: phosphatidylserine binding; calcium-dependent phospholipid binding; syntaxin binding; clathrin binding; SNARE binding. It is involved in the biological process described with: regulation of neurotransmitter secretion; synaptic vesicle exocytosis; positive regulation of vesicle fusion; neurotransmitter secretion; calcium ion-regulated exocytosis of neurotransmitter; vesicle-mediated transport; regulation of synaptic plasticity. 21 alleles are reported. The phenotypes of these alleles manifest in: wing vein; motor neuron; neuromuscular junction; NMJ bouton. The phenotypic classes of alleles include: neuroanatomy defective; fertile; viable; visible; neurophysiology defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0014075	Ugt	0.372459831	0.332464031	0.999936032	NA	UGGT1;UGGT2	high;moderate	NA	NA	NA	"The gene UDP-glucose-glycoprotein glucosyltransferase is referred to in FlyBase by the symbol Dmel\Ugt (CG6850, FBgn0014075). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:18872747..18878245. It has the cytological map location 75E3. Protein features are: Glycosyl transferase, family 8; Nucleotide-diphospho-sugar transferases; UDP-glucose:Glycoprotein Glucosyltransferase. Its molecular function is described by: UDP-glucose:glycoprotein glucosyltransferase activity; unfolded protein binding. It is involved in the biological process described with: 'de novo' posttranslational protein folding; ER-associated misfolded protein catabolic process; protein N-linked glycosylation via asparagine; protein glycosylation; endoplasmic reticulum unfolded protein response. 9 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0038485	CG5255	0.372688221	0.371446758	0.999936032	NA	KLK14	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5255 (FBgn0038485). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:17137893..17138865. It has the cytological map location 89F1. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0036105	Blos4	0.372688309	0.349286294	0.999936032	NA	BLOC1S4;BCAS4	high;moderate	NA	NA	NA	"The gene Biogenesis of lysosome-related organelles complex 1, subunit 4 is referred to in FlyBase by the symbol Dmel\Blos4 (CG14149, FBgn0036105). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:10879085..10880188. It has the cytological map location 67F1. Protein features are: Cappuccino. Its molecular function is described by: protein binding. It is involved in the biological process described with: eye pigment granule organization; intracellular transport. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable; eye color defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0032446	CG5780	0.372935806	0.374871224	0.999936032	NA	IFT43	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5780 (FBgn0032446). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:12693872..12694988. It has the cytological map location 33F3. Protein features are: Intraflagellar transport protein 43. Its molecular function is described by: . It is involved in the biological process described with: intraciliary retrograde transport; cilium assembly. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0000459	disco	0.373603587	0.373387591	0.999936032	NA	BNC2;BNC1	moderate;moderate	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene disconnected is referred to in FlyBase by the symbol Dmel\disco (CG9908, FBgn0000459). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:16210598..16216750. It has the cytological map location 14B3. Protein features are: Zinc finger C2H2-type. Its molecular function is described by: DNA binding; enhancer sequence-specific DNA binding. It is involved in the biological process described with 11 unique terms, many of which group under: rhythmic process; single-multicellular organism process; circadian behavior; eclosion rhythm; developmental process; head development; homeostatic process; carbohydrate metabolic process; imaginal disc-derived appendage development; central nervous system development. 27 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval digestive system; embryonic head; sensory system neuron; mechanosensory chaeta; pretarsus; larval metathoracic segment; cone cell; embryonic/larval optic stalk; sensory organ cell; pigment cell; gastrula embryo; eo-type sensillum. The phenotypic classes of alleles include: behavior defective; increased mortality; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0038110	CG8031	0.374047032	0.285320388	0.999936032	MEMO1	MEMO1	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG8031 (FBgn0038110). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:13008384..13011310. It has the cytological map location 87D8. Protein features are: MEMO1 family. Its molecular function is described by: . It is involved in the biological process described with: regulation of microtubule-based process. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed during early pupal stages.
FBgn0022700	Cht4	0.374066034	0.312335231	0.999936032	NA	CHIA;OVGP1;CHI3L2;CHI3L1;CHIT1	moderate;moderate;moderate;moderate;low	NA	NA	NA	"The gene Chitinase 4 is referred to in FlyBase by the symbol Dmel\Cht4 (CG3986, FBgn0022700). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:21065379..21067087. It has the cytological map location 57B16. Protein features are: Chitin binding domain; Chitinase II; Chitinase insertion domain; Glycoside hydrolase family 18, catalytic domain; Glycoside hydrolase superfamily; Glycoside hydrolase, chitinase active site. Its molecular function is described by: chitin binding; chitinase activity. It is involved in the biological process described with: chitin catabolic process; carbohydrate metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; some die during pupal stage; partially lethal - majority die; partially lethal - majority live; some die during larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during early larval stages, during early pupal stages.  "
FBgn0013685	mt:ND6	0.374537854	0.273753079	0.999936032	NA	ND6	low	NA	transmembrane protein	NA	"The gene mitochondrial NADH-ubiquinone oxidoreductase chain 6 is referred to in FlyBase by the symbol Dmel\mt:ND6 (CG34089, FBgn0013685). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is mitochondrion_genome:9971..10495. Protein features are: NADH:ubiquinone/plastoquinone oxidoreductase, chain 6. Its molecular function is described by: NADH dehydrogenase (ubiquinone) activity. It is involved in the biological process described with: oxidation-reduction process. 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely low expression to a trough of no expression detected.  Peak expression observed at stages throughout embryogenesis, during early larval stages, during early pupal stages, in adult female stages.  "
FBgn0035708	axed	0.374641432	0.33430999	0.999936032	NA	BTBD2;BTBD1	moderate;high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8398 (FBgn0035708). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3L:6609325..6619113. It has the cytological map location 65C1. Protein features are: BTB/Kelch-associated. Its molecular function is described by: ubiquitin protein ligase binding. It is involved in the biological process described with: neurogenesis; proteasome-mediated ubiquitin-dependent protein catabolic process; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; regulation of proteolysis. 21 alleles are reported. The phenotype of these alleles manifest in: axon. The phenotypic classes of alleles include: wound healing defective; lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 06-12 and 18-24 hour embryonic stages, during late pupal stages, in adult male stages.  "
FBgn0029093	cathD	0.374753508	0.269596539	0.999936032	NA	CTSD;NAPSA;REN;CTSE;PGC;PGA3;PGA4;PGA5;BACE2;BACE1	high;moderate;moderate;moderate;low;low;low;low;moderate;moderate	NA	NA	NA	"The gene cathD is referred to in FlyBase by the symbol Dmel\cathD (CG1548, FBgn0029093). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:7815339..7823569. It has the cytological map location 43E18. Protein features are: Aspartic peptidase A1 family; Aspartic peptidase domain; Aspartic peptidase, N-terminal; Aspartic peptidase, active site; Cathepsin D; Peptidase family A1 domain. Its molecular function is described by: aspartic-type endopeptidase activity. It is involved in the biological process described with: defense response to Gram-negative bacterium; proteolysis; apoptotic process; autophagic cell death; salivary gland cell autophagic cell death; protein catabolic process; nurse cell apoptotic process. 14 alleles are reported. The phenotypes of these alleles manifest in: male germline cell; eye; egg chamber; nurse cell; adult brain; spermatogonial cyst. The phenotypic classes of alleles include: decreased cell death; increased cell death; cell death defective; viable; short lived; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed during late larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0035677	CG13293	0.375042725	0.372007925	0.999936032	SCAI	SCAI	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13293 (FBgn0035677). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 3L:6082883..6092188. It has the cytological map location 65A5. Protein features are: Protein SCAI; Protein SCAI, metazoan/viridiplantae. Its molecular function is described by: transcription corepressor activity. It is involved in the biological process described with: transcription, DNA-templated. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 06-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period.  "
FBgn0036467	CG12310	0.375055341	0.32813143	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12310 (FBgn0036467). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:15050263..15050806. It has the cytological map location 71B2. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0040571	CG17193	0.375183993	0.179114511	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG17193 (FBgn0040571). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:20036421..20056097. It has the cytological map location 92C2-92C4. Its molecular function is described by: . It is involved in the biological process described with: . 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages.
FBgn0024196	robl	0.375663116	0.27685419	0.999936032	NA	DYNLRB2;DYNLRB1	high;moderate	NA	NA	NA	"The gene roadblock is referred to in FlyBase by the symbol Dmel\robl (CG10751, FBgn0024196). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:17456472..17457129. It has the cytological map location 54B16. Protein features are: Dynein light chain roadblock-type 1/2; Roadblock/LAMTOR2 domain. Its molecular function is described by: dynein intermediate chain binding; ATPase activity, coupled. It is involved in the biological process described with: dendrite morphogenesis; microtubule-based movement; mushroom body development. 15 alleles are reported. The phenotypes of these alleles manifest in: mitotic M phase; external sensory organ; mechanosensory sensory organ; mitotic cell cycle; anaphase; cell projection; pupa; segmental nerve; neuron part; mitotic telophase; cell cycle; trichogen cell. The phenotypic classes of alleles include: fertile; paralytic; increased mortality during development; viable; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0052600	dpr8	0.375844971	0.275141499	0.999936032	NA	NA	NA	NA	NA	NA	"The gene defective proboscis extension response 8 is referred to in FlyBase by the symbol Dmel\dpr8 (CG32600, FBgn0052600). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:14322226..14462351. It has the cytological map location 12E8-12E10. Protein features are: Immunoglobulin; Immunoglobulin I-set; Immunoglobulin V-set domain; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold. Its molecular function is described by: . It is involved in the biological process described with: sensory perception of chemical stimulus; synapse organization. 21 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, during late pupal stages.  "
FBgn0013275	Hsp70Aa	0.375860758	0.162699385	0.999936032	NA	HSPA1A;HSPA1B;HSPA1L;HSPA6;HSPA8;HSPA2;HSPA5	high;moderate;high;moderate;low;low;low	NA	NA	NA	"The gene Heat-shock-protein-70Aa is referred to in FlyBase by the symbol Dmel\Hsp70Aa (CG31366, FBgn0013275). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:11954163..11956544. It has the cytological map location 87A2. Protein features are: Heat shock protein 70 family; Heat shock protein 70, conserved site; Heat shock protein 70kD, C-terminal domain; Heat shock protein 70kD, peptide-binding domain. Its molecular function is unknown. It is involved in the biological process described with: heat shock-mediated polytene chromosome puffing; response to heat; response to hypoxia. 17 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed at stages throughout the pupal period.  "
FBgn0264598	PsGEF	0.376249733	0.306130929	0.999936032	NA	GRASP;USH1C;DOC2B;PARD3B;ARHGEF10;LNX1;FRMPD2;RPH3A;PATJ;DLG5;ARHGEF10L;IL16;PDZD2;RPH3AL;GRID2IP;GRIP1;MPDZ	low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low	NA	NA	NA	"The gene Protostome-specific GEF is referred to in FlyBase by the symbol Dmel\PsGEF (CG43947, FBgn0264598). It is a protein_coding_gene from Drosophila melanogaster. It has 8 annotated transcripts and 8 polypeptides (all unique). Gene sequence location is X:2367121..2387664. It has the cytological map location 3A2. Protein features are: C2 domain; Dbl homology (DH) domain; PDZ domain; PH domain-like; Protein of unknown function DUF4799. Its molecular function is described by: Rho guanyl-nucleotide exchange factor activity; calcium-dependent phospholipid binding. It is involved in the biological process described with: regulation of Rho protein signal transduction; positive regulation of Rac protein signal transduction; mushroom body development; positive regulation of ruffle assembly; regulation of actin filament polymerization. 12 alleles are reported. The phenotype of these alleles manifest in: mushroom body alpha-lobe. The phenotypic classes of alleles include: neuroanatomy defective; fertile; viable."
FBgn0033459	CG12744	0.376383709	0.332726359	0.999936032	NA	PRDM10;ZNF770	low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12744 (FBgn0033459). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:9874889..9876242. It has the cytological map location 46C1. Protein features are: Zinc finger C2H2-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: nucleic acid binding. It is involved in the biological process described with: defense response to fungus. 20 alleles are reported. The phenotypes of these alleles manifest in: crystal cell; hemocyte. The phenotypic classes of alleles include: viable; fertile; immune response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, in adult female stages.  "
FBgn0035444	CG12012	0.376579983	0.279063856	0.999936032	NA	BRI3	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12012 (FBgn0035444). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:3376757..3377992. It has the cytological map location 63D2. Protein features are: Brain protein I3. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0000524	dx	0.376690799	0.365128359	0.999936032	NA	DTX1;DTX4;DTX2;UPK3B;DTX3;DTX3L	high;moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"The gene deltex is referred to in FlyBase by the symbol Dmel\dx (CG3929, FBgn0000524). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:6533999..6538575. It has the cytological map location 6B1-6B2. Protein features are: WWE domain; WWE domain, subgroup; Zinc finger, RING-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: ubiquitin protein ligase activity; zinc ion binding; Notch binding. It is involved in the biological process described with: negative regulation of Notch signaling pathway; Wnt signaling pathway; imaginal disc-derived leg joint morphogenesis; protein ubiquitination; positive regulation of Notch signaling pathway; regulation of Notch signaling pathway; endocytosis; Notch receptor processing; wing disc development; Notch signaling pathway. 37 alleles are reported. The phenotypes of these alleles manifest in: compound sense organ; ommatidium; abdominal lateral adult muscle precursor cell; pupa; optic lobe neuron; larva; proneural cluster; larval mesothoracic segment; abdominal adult muscle precursor cell; larval thoracic segment. The phenotypic classes of alleles include: partially lethal; increased mortality during development; flight defective; phenotype; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0266000	CG44774	0.376835674	0.340694109	0.999936032	NA	FAM60A	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG44774 (FBgn0266000). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (2 unique). Gene sequence location is X:4921678..4938105. It has the cytological map location 4D6. Protein features are: FAM60A. Its molecular function is described by: . It is involved in the biological process described with: negative regulation of cell migration. 27 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: body color defective; viable; visible.
FBgn0036316	CG10960	0.376941185	0.277111175	0.999936032	NA	SLC2A8;SLC2A6	moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10960 (FBgn0036316). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:12824880..12843106. It has the cytological map location 69E5-69E6. Protein features are: Major facilitator superfamily domain; Major facilitator,  sugar transporter-like; Sugar transporter, conserved site; Sugar/inositol transporter. Its molecular function is described by: sugar:proton symporter activity; glucose transmembrane transporter activity. It is involved in the biological process described with: positive regulation of JAK-STAT cascade; hexose transmembrane transport; glucose import. 11 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0032211	CG13138	0.377278303	0.235085419	0.999936032	NA	GGN;TPRX1	low;low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG13138 (FBgn0032211). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:10299977..10302018. It has the cytological map location 31D1. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages.
FBgn0265084	CG44195	0.377280336	0.209040235	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG44195 (FBgn0265084). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:7658409..7695654. It has the cytological map location 66A8-66A9. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available.
FBgn0037703	JHDM2	0.377361557	0.368661326	0.999936032	NA	KDM3B;JMJD1C;KDM3A;HR	high;high;moderate;moderate	NA	NA	NA	"The gene JmjC domain-containing histone demethylase 2 is referred to in FlyBase by the symbol Dmel\JHDM2 (CG8165, FBgn0037703). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:9516007..9520938. It has the cytological map location 85D19. Protein features are: JmjC domain. Its molecular function is described by: transcription regulatory region sequence-specific DNA binding; chromatin DNA binding; histone demethylase activity; histone demethylase activity (H3-K9 specific). It is involved in the biological process described with: positive regulation of chromatin silencing; histone H3-K9 demethylation; histone demethylation. 11 alleles are reported. The phenotypes of these alleles manifest in: adult salivary gland; eye-antennal disc. The phenotypic classes of alleles include: fertile; viable; suppressor of variegation. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0052568	CG32568	0.377693631	0.361721855	0.999936032	NA	PPP2R5E;PPP2R5B;PPP2R5A;PPP2R5C;PPP2R5D	moderate;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32568 (FBgn0052568). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:16740906..16742918. It has the cytological map location 15A3. Protein features are: Armadillo-like helical; Armadillo-type fold; Protein phosphatase 2A, regulatory B subunit, B56. Its molecular function is described by: protein phosphatase regulator activity. It is involved in the biological process described with: signal transduction. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed at stages throughout the pupal period, in adult male stages.  "
FBgn0034417	CG15117	0.377882334	0.288224781	0.999936032	GUSB	GUSB	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15117 (FBgn0034417). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (5 unique). Gene sequence location is 2R:19122231..19129300. It has the cytological map location 56B5. Protein features are: Galactose-binding domain-like; Glycoside hydrolase family 2, catalytic domain; Glycoside hydrolase superfamily; Glycoside hydrolase, family 2; Glycoside hydrolase, family 2, active site; Glycoside hydrolase, family 2, conserved site; Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich; Glycosyl hydrolases family 2, sugar binding domain; Immunoglobulin-like fold. Its molecular function is described by: hydrolase activity, hydrolyzing O-glycosyl compounds. It is involved in the biological process described with: multicellular organism reproduction; carbohydrate metabolic process. 7 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum. The phenotypic classes of alleles include: some die during pupal stage; partially lethal - majority die; visible; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, in adult male stages.  "
FBgn0035248	CG13919	0.378151285	0.308352568	0.999936032	NA	TMEM60	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13919 (FBgn0035248). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:1645467..1645983. It has the cytological map location 62A9. Protein features are: Transmembrane Fragile-X-F-associated protein. Its molecular function is described by: . It is involved in the biological process described with: . 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0029657	CG12535	0.378334369	0.28654445	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12535 (FBgn0029657). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is X:3387944..3448943. It has the cytological map location 3D2-3D3. Its molecular function is unknown. The biological processes in which it is involved are not known. 11 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed at stages throughout the pupal period, in adult male stages.  "
FBgn0031580	CG15423	0.378776476	0.264232679	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15423 (FBgn0031580). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:4006041..4006606. It has the cytological map location 24D3. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0032088	CG13102	0.379036795	0.264296394	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13102 (FBgn0032088). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:9012188..9014149. It has the cytological map location 29F7. Its molecular function is unknown. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages.  "
FBgn0035833	CG7565	0.379066714	0.308349058	0.999936032	KIAA0319	KIAA0319L;KIAA0319	high;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7565 (FBgn0035833). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:8087635..8091786. It has the cytological map location 66B5. Protein features are: Immunoglobulin-like fold; MANSC domain; PKD domain; PKD/Chitinase domain; Seven cysteines, N-terminal. Its molecular function is unknown. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal; short lived; lethal - all die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.  "
FBgn0267253	CG32700	0.379283947	0.319515343	0.999936032	NA	NA	NA	Maybe TF	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG32700 (FBgn0267253). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:9502826..9550838. It has the cytological map location 8E4. Its molecular function is described by: . It is involved in the biological process described with: . 12 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable.
FBgn0000810	fs(1)K10	0.379749879	0.366254505	0.999936032	NA	CHTF8	low	NA	NA	NA	"The gene female sterile (1) K10 is referred to in FlyBase by the symbol Dmel\fs(1)K10 (CG3218, FBgn0000810). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:2242138..2246041. It has the cytological map location 2F1-2F2. Protein features are: WD40/YVTN repeat-like-containing domain. Its molecular function is described by: DNA binding. It is involved in the biological process described with: dorsal/ventral pattern formation; protein localization; pole plasm mRNA localization; negative regulation of translation; ovarian follicle cell development; oogenesis; intracellular mRNA localization. 82 alleles are reported. The phenotypes of these alleles manifest in: epidermis; filzkorper; embryo; egg; oocyte; dorsal appendage; chorion; egg chamber; follicle cell. The phenotypic classes of alleles include: lethal - all die before end of embryonic stage; female sterile; wild-type; some die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0085475	CG34446	0.381423006	0.346923368	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG34446 (FBgn0085475). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:22647458..22647807. It has the cytological map location 58F3. Protein features are: LPS-induced tumour necrosis factor alpha factor. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages.
FBgn0052845	CG32845	0.381712505	0.328981052	0.999936032	NA	PIN1	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32845 (FBgn0052845). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:271420..273391. It has the cytological map location 61B3. Protein features are: Peptidyl-prolyl cis-trans isomerase, PpiC-type; Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site; WW domain. Its molecular function is described by: isomerase activity. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 06-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0264510	CR43909	0.382173181	0.303907133	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR43909 (FBgn0264510). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2R:12594392..12595649. It has the cytological map location 49B7. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0030505	NFAT	0.382480584	0.304130996	0.999936032	NA	NFATC2;NFATC3;NFAT5;NFATC4;NFATC1	high;high;high;moderate;moderate	DNA-binding with transcription factor activity(RHD|TIG)	NA	NA	"The gene NFAT nuclear factor is referred to in FlyBase by the symbol Dmel\NFAT (CG11172, FBgn0030505). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (6 unique). Gene sequence location is X:13624745..13664568. It has the cytological map location 12A9-12B2. Protein features are: IPT domain; Immunoglobulin E-set; Immunoglobulin-like fold; Nuclear factor of activated T cells (NFAT); Rel homology dimerisation domain; Rel homology domain (RHD), DNA-binding domain; Tetratricopeptide-like helical domain; WD40/YVTN repeat-like-containing domain; p53-like transcription factor, DNA-binding. Its molecular function is described by: DNA binding; transcription factor activity, sequence-specific DNA binding. It is involved in the biological process described with: response to salt stress; negative regulation of synaptic vesicle exocytosis; regulation of transcription, DNA-templated; negative regulation of Ras protein signal transduction. 53 alleles are reported. The phenotypes of these alleles manifest in: synapse; compound cell cluster organ; embryo; embryonic/larval alimentary canal; pupa; head; neuromuscular junction; sensory organ cell; cuticular specialization; embryonic/larval anal pad. The phenotypic classes of alleles include: lethal - all die before end of second instar larval stage; increased mortality; fertile; circadian rhythm defective; phenotype; viable; partially lethal - majority live. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period.  "
FBgn0036118	Blos2	0.382788752	0.31768416	0.999936032	NA	BLOC1S2	high	NA	NA	NA	"The gene Biogenesis of lysosome-related organelles complex 1, subunit 2 is referred to in FlyBase by the symbol Dmel\Blos2 (CG14145, FBgn0036118). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:11061571..11062215. It has the cytological map location 68A3. Protein features are: Biogenesis of lysosome-related organelles complex-1, subunit 2. Its molecular function is described by: oxidoreductase activity; protein homodimerization activity; protein binding. It is involved in the biological process described with: . 5 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0028916	CG33090	0.38301784	0.315783428	0.999936032	NA	GBA2	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG33090 (FBgn0028916). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 2L:14334158..14345795. It has the cytological map location 35A4. Protein features are: Beta-glucosidase GBA2-type; Glycosyl-hydrolase family 116, N-terminal; Glycosyl-hydrolase family 116, catalytic region; Six-hairpin glycosidase-like. Its molecular function is described by: glucosylceramidase activity; beta-glucosidase activity. It is involved in the biological process described with: bile acid metabolic process; glucosylceramide catabolic process; glycoside catabolic process. 12 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0000183	BicD	0.383722226	0.295193714	0.999936032	NA	BICD2;BICD1	high;moderate	NA	NA	NA	"The gene Bicaudal D is referred to in FlyBase by the symbol Dmel\BicD (CG6605, FBgn0000183). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 2L:17459605..17473215. It has the cytological map location 36C9. Protein features are: Bicaudal-D protein, microtubule-associated. Its molecular function is described by: dynein complex binding; clathrin heavy chain binding; Rab GTPase binding; protein binding. It is involved in the biological process described with 15 unique terms, many of which group under: establishment or maintenance of microtubule cytoskeleton polarity; cellular macromolecule localization; germarium-derived oocyte differentiation; oocyte dorsal/ventral axis specification; positive regulation of cellular component organization; germarium-derived egg chamber formation; organic substance transport; nucleic acid transport; macromolecule localization; positive regulation of endocytosis; regulation of regulated secretory pathway; RNA localization. 69 alleles are reported. The phenotypes of these alleles manifest in: compound sense organ; dorsal appendage; embryonic neuroblast; membrane-enclosed lumen; somatic precursor cell; cytoskeletal part; external encapsulating structure; egg operculum; neuron part; embryonic thorax; anatomical space; embryonic/first instar larval cuticle; gastrula embryo; oocyte nucleus. The phenotypic classes of alleles include: fertile; phenotype; increased mortality during development; sterile; wild-type; behavior defective; partially lethal; male fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0011739	wts	0.384186992	0.347099268	0.999936032	NA	LATS2;LATS1;STK38L;STK38	high;moderate;low;low	NA	NA	NA	"The gene warts is referred to in FlyBase by the symbol Dmel\wts (CG12072, FBgn0011739). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:30789625..30806619. It has the cytological map location 100A5. Protein features are: AGC-kinase, C-terminal; Armadillo-like helical; Protein kinase domain; Protein kinase, ATP binding site; Protein kinase-like domain; Serine/threonine-protein kinase LATS1/ Warts; Serine/threonine-protein kinase, active site. Its molecular function is described by: protein binding; protein serine/threonine kinase activity; ATP binding. It is involved in the biological process described with 24 unique terms, many of which group under: regulation of cellular component organization; cellular nitrogen compound metabolic process; sexual reproduction; peptidyl-serine modification; small molecule metabolic process; respiratory system development; apical protein localization; eye morphogenesis; response to ionizing radiation; stem cell proliferation; protein localization; G1/S transition of mitotic cell cycle; response to radiation; regulation of glial cell proliferation; hippo signaling; regulation of biological quality; ameboidal-type cell migration; regulation of nitrogen compound metabolic process; eye photoreceptor cell differentiation; regulation of dendrite development. 121 alleles are reported. The phenotypes of these alleles manifest in: ganglion; type II neuroblast; sensory cluster; plasma membrane bounded cell projection; cell cycle; eye disc posterior to the morphogenetic furrow; photoreceptor cell R8 of yellow ommatidium; mitotic spindle; ovary; embryonic/larval neuron. The phenotypic classes of alleles include: sterile; some die during larval stage; size defective; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0035137	CG1233	0.384397551	0.322335562	0.999936032	NA	ZNF787;ZNF316;ZBTB49;ZBTB10;PRDM5;ZBTB46;ZBTB7C	low;low;low;low;low;low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1233 (FBgn0035137). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:361472..365681. It has the cytological map location 61C1. Protein features are: Zinc finger C2H2-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: nucleic acid binding. The biological processes in which it is involved are not known. 8 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: visible; viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0085364	MRE16	0.384456264	0.260275605	0.999936032	NA	NA	NA	NA	NA	NA	NA
FBgn0050360	Mal-A6	0.384525036	0.256818418	0.999936032	NA	SLC3A1;SLC3A2	moderate;low	NA	transmembrane protein	NA	"The gene Maltase A6 is referred to in FlyBase by the symbol Dmel\Mal-A6 (CG30360, FBgn0050360). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:8465158..8467595. It has the cytological map location 44D1. Protein features are: Glycoside hydrolase superfamily; Glycosyl hydrolase, family 13, catalytic domain. Its molecular function is described by: catalytic activity. It is involved in the biological process described with: carbohydrate metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during early larval stages, in stages of adults of both sexes.  "
FBgn0243512	puc	0.384672313	0.272120075	0.999936032	NA	DUSP10;DUSP8;DUSP16;SSH3;SSH2;DUSP4;DUSP1;DUSP6;DUSP18;DUSP7;DUSP2;DUSP27;SSH1;STYX;DUSP5;DUSP3;DUSP19;DUPD1;DUSP13	high;moderate;moderate;low;low;moderate;moderate;low;low;low;moderate;low;low;low;moderate;low;low;low;low	NA	NA	NA	"The gene puckered is referred to in FlyBase by the symbol Dmel\puc (CG7850, FBgn0243512). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:8105332..8122294. It has the cytological map location 84E12-84E13. Protein features are: Dual specificity phosphatase; Dual specificity phosphatase, catalytic domain; Dual specificity protein phosphatase domain; Protein-tyrosine phosphatase, active site; Protein-tyrosine phosphatase-like; Tyrosine specific protein phosphatases domain. Its molecular function is described by: JUN kinase phosphatase activity; phosphoprotein phosphatase activity; MAP kinase tyrosine/serine/threonine phosphatase activity; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity. It is involved in the biological process described with 33 unique terms, many of which group under: response to oxidative stress; positive regulation of metabolic process; embryonic organ morphogenesis; cuticle development; determination of bilateral symmetry; organic substance transport; positive regulation of organelle organization; positive regulation of cell differentiation; sensory organ development; compound eye development. 69 alleles are reported. The phenotypes of these alleles manifest in: larva; embryonic/larval digestive system; larval thoracic segment; pupa; germline cell; presumptive embryonic/larval peripheral nervous system; bouton; optic lobe neuron; cell part; midline; adult labral segment; synapse. The phenotypic classes of alleles include: partially lethal; stress response defective; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 12-24 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0259707	CG42361	0.384783758	0.316374338	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG42361 (FBgn0259707). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:24607673..24608788. It has the cytological map location 60D9. Protein features are: Predicted HD phosphohydrolase. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period.  "
FBgn0035355	CG16985	0.384956801	0.274615269	0.999936032	NA	ACOT13	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG16985 (FBgn0035355). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:2599297..2600242. It has the cytological map location 62E7. Protein features are: HotDog domain; Phenylacetic acid degradation-related domain; Thioesterase domain. Its molecular function is described by: acyl-CoA hydrolase activity. It is involved in the biological process described with: protein homotetramerization. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0051998	CG31998	0.385806762	0.313690077	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31998 (FBgn0051998). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 4:196675..205945. It has the cytological map location 102A7. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die during P-stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0033720	CG13160	0.386128371	0.341700466	0.999936032	ERMP1	ERMP1	moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13160 (FBgn0033720). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:12371594..12375081. It has the cytological map location 49A1. Protein features are: Peptidase M28. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0266572	ebo	0.386241721	0.320631142	0.999936032	NA	XPO6	high	NA	transmembrane protein	NA	"The gene ellipsoid body open is referred to in FlyBase by the symbol Dmel\ebo (CG3923, FBgn0266572). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is X:471019..476579. It has the cytological map location 1B4. Protein features are: Armadillo-like helical; Armadillo-type fold; Exportin-1/Importin-beta-like; Importin-beta, N-terminal domain. Its molecular function is described by: Ran GTPase binding. It is involved in the biological process described with: adult walking behavior; mushroom body development; central complex development; flight behavior; short-term memory; intracellular protein transport. 11 alleles are reported. The phenotypes of these alleles manifest in: calyx of adult mushroom body; lobe system of adult mushroom body; adult mushroom body; fan-shaped body; ellipsoid body; optic lobe. The phenotypic classes of alleles include: behavior defective; phenotype; increased mortality during development; increased mortality."
FBgn0003053	peb	0.38625614	0.282161543	0.999936032	NA	RREB1	high	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene pebbled is referred to in FlyBase by the symbol Dmel\peb (CG12212, FBgn0003053). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:4617564..4627206. It has the cytological map location 4C10. Protein features are: WD40/YVTN repeat-like-containing domain; Zinc finger C2H2-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: sequence-specific DNA binding; transcription factor activity, sequence-specific DNA binding; transcription regulatory region DNA binding. It is involved in the biological process described with 24 unique terms, many of which group under: respiratory system development; dorsal/ventral pattern formation; negative regulation of phosphorylation; single-organism nuclear import; zygotic determination of anterior/posterior axis, embryo; epithelium migration; ectoderm development; regulation of protein localization to plasma membrane; regulation of cell-cell adhesion; wing disc pattern formation; regulation of protein phosphorylation; gamete generation. 38 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval digestive system; cell projection; embryonic tagma; prepupa; ommatidial precursor cluster; gastrula embryo; squamous epithelium; eye disc; axon; plasma membrane bounded cell projection; cell part. The phenotypic classes of alleles include: visible; viable; phenotype; lethal - all die before end of larval stage; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages.  "
FBgn0053983	obst-H	0.386448271	0.294188625	0.999936032	NA	NA	NA	NA	NA	NA	"The gene obstructor-H is referred to in FlyBase by the symbol Dmel\obst-H (CG33983, FBgn0053983). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:15528265..15529243. It has the cytological map location 71E1. Protein features are: Chitin binding domain. Its molecular function is described by: chitin binding. It is involved in the biological process described with: chitin metabolic process. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0037882	CG17187	0.386720736	0.356867369	0.999936032	NA	DNAJC17	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17187 (FBgn0037882). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:11230617..11231879. It has the cytological map location 86D8. Protein features are: DNAJC17, RNA recognition motif; DnaJ domain; RNA recognition motif domain. Its molecular function is described by: nucleic acid binding. It is involved in the biological process described with: mRNA splicing, via spliceosome. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: phenotype; increased mortality during development; increased mortality; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0005624	Psc	0.386928594	0.35103964	0.999936032	NA	BMI1;PCGF2;COMMD3-BMI1;PCGF5	high;low;moderate;low	DNA-binding with transcription factor activity	NA	NA	"The gene Posterior sex combs is referred to in FlyBase by the symbol Dmel\Psc (CG3886, FBgn0005624). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:12965997..12980994. It has the cytological map location 49E6. Protein features are: RAWUL domain; Zinc finger, RING-type; Zinc finger, RING-type, conserved site; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: zinc ion binding; core promoter binding; DNA binding. It is involved in the biological process described with: chromatin silencing; axon guidance; chromatin remodeling; ventral cord development; syncytial blastoderm mitotic cell cycle. 55 alleles are reported. The phenotypes of these alleles manifest in: cell cycle phase; biological phase; embryonic/larval cuticle; telophase; female organism; mechanosensory sensory organ; mesothoracic leg; metatarsus of male prothoracic leg; denticle belt; pigment cell; compartment; embryonic head; sensillum. The phenotypic classes of alleles include: visible; phenotype; increased mortality during development; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0035424	CG11505	0.387072936	0.289222408	0.999936032	NA	LARP4;LARP4B	high;moderate	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG11505 (FBgn0035424). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:3224838..3236604. It has the cytological map location 63C1. Protein features are: La-type HTH domain; RNA recognition motif domain; Winged helix-turn-helix DNA-binding domain. Its molecular function is described by: nucleic acid binding. It is involved in the biological process described with: . 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0035497	CG14995	0.387361902	0.352707276	0.999936032	NA	C21orf2	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14995 (FBgn0035497). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (all unique). Gene sequence location is 3L:4094343..4103256. It has the cytological map location 64A5-64A6. Protein features are: Leucine-rich repeat; Leucine-rich repeat domain, L domain-like; WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. It is involved in the biological process described with: autophagic cell death; salivary gland cell autophagic cell death. 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed at stages throughout the pupal period, in adult male stages.  "
FBgn0003396	shn	0.387460645	0.284262958	0.999936032	NA	HIVEP2;HIVEP3;HIVEP1;ZNF831	high;moderate;moderate;moderate	DNA-binding with transcription factor activity(zf-C2H2)	transmembrane protein	NA	"The gene schnurri is referred to in FlyBase by the symbol Dmel\shn (CG7734, FBgn0003396). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (3 unique). Gene sequence location is 2R:11159086..11217394. It has the cytological map location 47D6-47D7. Protein features are: Matrin/U1-C-like, C2H2-type zinc finger; WD40/YVTN repeat-like-containing domain; Zinc finger C2H2-type; Zinc finger CCHC HIVEP-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: zinc ion binding; sequence-specific DNA binding; transcription regulatory region DNA binding; transcription factor activity, sequence-specific DNA binding; transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; RNA polymerase II activating transcription factor binding; RNA polymerase II transcription coactivator activity. It is involved in the biological process described with 23 unique terms, many of which group under: eye development; cell surface receptor signaling pathway; regulation of organ morphogenesis; neuron projection development; negative regulation of multicellular organismal process; positive regulation of RNA metabolic process; cellular response to growth factor stimulus; chemosensory behavior; embryonic hindgut morphogenesis; cell proliferation. 101 alleles are reported. The phenotypes of these alleles manifest in: external compound sense organ; abdominal segment; trichome field; mesoderm; excretory system; dorsal multidendritic neuron ddaD; embryonic/larval midgut primordium; spiracular chamber; dorsal multidendritic neuron ddaC; ovariole; embryonic dorsal epidermis; multi-cell-component structure; chordotonal organ; embryonic/larval hemocoel. The phenotypic classes of alleles include: cytokinesis defective; phenotype; lethal - all die before end of prepupal stage; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0027521	CG3679	0.387614174	0.345220125	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG3679 (FBgn0027521). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:16303870..16307377. It has the cytological map location 14B9. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. The phenotypes of these alleles manifest in: indirect flight muscle; trichogen cell; Z disc; sarcomere; myofibril. The phenotypic classes of alleles include: flightless; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0030590	CG9518	0.387659183	0.224765069	0.999936032	NA	CHDH	moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9518 (FBgn0030590). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is X:14862989..14871181. It has the cytological map location 12F6-12F7. Protein features are: FAD/NAD(P)-binding domain; Glucose-methanol-choline oxidoreductase; Glucose-methanol-choline oxidoreductase, C-terminal; Glucose-methanol-choline oxidoreductase, N-terminal. Its molecular function is described by: oxidoreductase activity; flavin adenine dinucleotide binding; oxidoreductase activity, acting on CH-OH group of donors. It is involved in the biological process described with: oxidation-reduction process; response to endoplasmic reticulum stress; ecdysteroid metabolic process; lateral inhibition. 3 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; chaeta. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-18 embryonic stages.  "
FBgn0028704	Nckx30C	0.38775833	0.328785265	0.999936032	NA	SLC24A2;SLC24A1;SLC24A4;SLC24A5	high;moderate;low;low	NA	transmembrane protein	NA	"The gene Nckx30C is referred to in FlyBase by the symbol Dmel\Nckx30C (CG18660, FBgn0028704). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 2L:9711512..9746495. It has the cytological map location 30C6-30C7. Protein features are: Sodium/calcium exchanger membrane region; Sodium/potassium/calcium exchanger; Sodium/potassium/calcium exchanger NCKX30C-like. Its molecular function is described by: calcium ion binding; calcium channel activity; calcium, potassium:sodium antiporter activity; sodium ion binding; potassium ion binding. It is involved in the biological process described with: sodium ion transport; cellular calcium ion homeostasis; calcium ion transport; neuron projection morphogenesis; transmembrane transport; compound eye development. 20 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages.  "
FBgn0085359	CG34330	0.388192796	0.253386784	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG34330 (FBgn0085359). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:19068275..19068973. It has the cytological map location 18A2. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; ganglion mother cell. The phenotypic classes of alleles include: lethal - all die during P-stage; viable; visible; lethal; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during late larval stages, during early pupal stages, in stages of adults of both sexes.  "
FBgn0010355	Taf1	0.388356761	0.350294935	0.999936032	NA	TAF1L;TAF1	high;high	DNA-binding with transcription factor activity(AT_hook)	NA	NA	"The gene TBP-associated factor 1 is referred to in FlyBase by the symbol Dmel\Taf1 (CG17603, FBgn0010355). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (all unique). Gene sequence location is 3R:6646889..6656048. It has the cytological map location 84A1. Protein features are: AT hook, DNA-binding motif; Bromodomain; Bromodomain, conserved site; TAFII-230 TBP-binding; Transcription initiation factor TFIID subunit 1, animal; Transcription initiation factor TFIID subunit 1, domain of unknown function. Its molecular function is described by: RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly; protein serine/threonine kinase activity; histone acetyltransferase activity (H3-K14 specific); transcription regulatory region DNA binding; transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly; H4 histone acetyltransferase activity; TBP-class protein binding; transcription factor binding; sequence-specific DNA binding. It is involved in the biological process described with: DNA-templated transcription, initiation; positive regulation of transcription initiation from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; protein phosphorylation; histone H3-K14 acetylation; histone H4 acetylation; positive regulation of transcription of Notch receptor target; transcription initiation from RNA polymerase II promoter; RNA polymerase II transcriptional preinitiation complex assembly; regulation of JAK-STAT cascade. 31 alleles are reported. The phenotypes of these alleles manifest in: cell; sensory neuron; intracellular non-membrane-bounded organelle; gamete; embryonic/larval neuroblast; late embryo; intracellular part; ganglion mother cell; mesothoracic tergum; male organism. The phenotypic classes of alleles include: partially lethal; lethal; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0001078	ftz-f1	0.389224479	0.302703614	0.999936032	NA	NR5A1;NR5A2	high;high	DNA-binding with transcription factor activity(zf-C4)	NA	NA	"The gene ftz transcription factor 1 is referred to in FlyBase by the symbol Dmel\ftz-f1 (CG4059, FBgn0001078). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 3L:18750607..18801309. It has the cytological map location 75D8-75E1. Protein features are: Nuclear hormone receptor; Nuclear hormone receptor family 5; Nuclear hormone receptor, ligand-binding domain; Zinc finger, NHR/GATA-type; Zinc finger, nuclear hormone receptor-type. Its molecular function is described by: steroid hormone receptor activity; transcription regulatory region sequence-specific DNA binding; DNA binding; RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding; zinc ion binding; transcription factor binding; protein heterodimerization activity; transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding; chromatin binding. It is involved in the biological process described with 21 unique terms, many of which group under: response to endogenous stimulus; brain development; cell maturation; regulation of biological quality; single-organism behavior; neuron projection morphogenesis; instar larval or pupal morphogenesis; response to organic cyclic compound; pupation; lipid homeostasis; positive regulation of cellular metabolic process; segmentation. 83 alleles are reported. The phenotypes of these alleles manifest in: cell cluster organ; intracellular non-membrane-bounded organelle; procuticle; dorsal multidendritic neuron ddaC; abdominal segment 8; parasegment 4; abdominal segment 3; intracellular part; external sensory organ; larval thoracic neuromere. The phenotypic classes of alleles include: cell death defective; lethal - all die before end of larval stage; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages.  "
FBgn0027356	Amph	0.389380415	0.30961242	0.999936032	NA	BIN1;AMPH;BIN2	high;high;moderate	NA	NA	NA	"The gene Amphiphysin is referred to in FlyBase by the symbol Dmel\Amph (CG8604, FBgn0027356). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 2R:12593604..12612068. It has the cytological map location 49B7-49B8. Protein features are: Amphiphysin; Arfaptin homology (AH) domain/BAR domain; BAR domain; SH3 domain. Its molecular function is described by: phospholipid binding. It is involved in the biological process described with: rhabdomere development; exocytosis; protein localization; rhabdomere membrane biogenesis; regulation of muscle contraction. 32 alleles are reported. The phenotypes of these alleles manifest in: motor neuron; neuromuscular junction; rhabdomere; indirect flight muscle; macrochaeta; NMJ bouton; T-tubule. The phenotypic classes of alleles include: viable; neurophysiology defective; fertile; flightless; hypoactive; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed during late pupal stages.  "
FBgn0033480	mRpL42	0.389429538	0.288663146	0.999936032	NA	MRPL42	high	NA	NA	NA	"The gene mitochondrial ribosomal protein L42 is referred to in FlyBase by the symbol Dmel\mRpL42 (CG12921, FBgn0033480). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:10066650..10067242. It has the cytological map location 46E1. Protein features are: Ribosomal protein S32, mitochondrial. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation. 7 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: lethal - all die during P-stage; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed during late pupal stages.  "
FBgn0025936	Eph	0.389878271	0.303521883	0.999936032	NA	EPHB1;EPHB2;EPHA4;EPHA7;EPHA3;EPHA2;EPHB4;EPHB3;EPHA5;EPHA6;EPHA8;EPHA1;EPHA10;EPHB6	high;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene Eph receptor tyrosine kinase is referred to in FlyBase by the symbol Dmel\Eph (CG1511, FBgn0025936). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (5 unique). Gene sequence location is 4:610684..622470. It has the cytological map location 102D1. Protein features are: Ephrin receptor ligand binding domain; Ephrin receptor type-A /type-B; Ephrin receptor, transmembrane domain; Fibronectin type III; Galactose-binding domain-like; Growth factor receptor cysteine-rich domain; Immunoglobulin-like fold; Protein kinase domain; Protein kinase, ATP binding site; Protein kinase-like domain; Serine-threonine/tyrosine-protein kinase, catalytic domain; Sterile alpha motif domain; Sterile alpha motif/pointed domain; Tyrosine-protein kinase ephrin type A/B receptor-like; Tyrosine-protein kinase, active site; Tyrosine-protein kinase, catalytic domain; Tyrosine-protein kinase, receptor class V, conserved site. Its molecular function is described by: ATP binding; transmembrane-ephrin receptor activity; protein tyrosine kinase activity. It is involved in the biological process described with: melanotic encapsulation of foreign target; protein autophosphorylation; peripheral nervous system development; regulation of glucose metabolic process; mushroom body development; protein phosphorylation; ephrin receptor signaling pathway. 23 alleles are reported. The phenotypes of these alleles manifest in: medial lobe of adult mushroom body; fascicle; medulla anlage; cell body rind of medulla; vertical lobe of adult mushroom body; embryonic/larval optic lobe; lobula; cell body rind of lobula plate. The phenotypic classes of alleles include: partially lethal - majority die; neuroanatomy defective; increased mortality; fertile; phenotype; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 12-18 hour embryonic stages.  "
FBgn0032688	CG15160	0.390175989	0.348645011	0.999936032	NA	RPRD2;RPRD1A;RPRD1B	high;low;low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG15160 (FBgn0032688). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 2L:18590891..18595429. It has the cytological map location 36F6. Protein features are: CID domain; Cell-cycle alteration and expression-elevated protein in tumour; ENTH/VHS; RNA polymerase II-binding domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: . It is involved in the biological process described with: mRNA 3'-end processing. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.
FBgn0014861	Mcm2	0.391017548	0.317800462	0.999936032	NA	MCM2	high	NA	NA	NA	"The gene Minichromosome maintenance 2 is referred to in FlyBase by the symbol Dmel\Mcm2 (CG7538, FBgn0014861). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:8264970..8267924. It has the cytological map location 84F6. Protein features are: DNA replication licensing factor Mcm2; MCM N-terminal domain; MCM OB domain; MCM domain; Mini-chromosome maintenance protein; Mini-chromosome maintenance, conserved site; Nucleic acid-binding, OB-fold; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: 3'-5' DNA helicase activity; DNA binding; ATP binding. It is involved in the biological process described with: DNA replication; DNA replication initiation; lateral inhibition; chromosome condensation. 7 alleles are reported. The phenotypes of these alleles manifest in: central nervous system; trichogen cell; imaginal disc; ganglion mother cell; embryonic/larval neuroblast; chaeta. The phenotypic classes of alleles include: some die during immature adult stage; neuroanatomy defective; viable; visible; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0039900	Syt7	0.391017548	0.317800462	0.999936032	NA	SYT7	high	NA	transmembrane protein	NA	"The gene Synaptotagmin 7 is referred to in FlyBase by the symbol Dmel\Syt7 (CG2381, FBgn0039900). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 4:278685..306481. It has the cytological map location 102B3. Protein features are: C2 domain; Synaptotagmin; Synaptotagmin 7. Its molecular function is described by: calcium-dependent phospholipid binding; syntaxin binding; clathrin binding; calcium ion binding. It is involved in the biological process described with: vesicle-mediated transport; calcium ion-regulated exocytosis of neurotransmitter; regulation of calcium ion-dependent exocytosis; neurotransmitter secretion; synaptic vesicle exocytosis; vesicle fusion. 14 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during late pupal stages.  "
FBgn0028426	JhI-1	0.391447776	0.331468857	0.999936032	NA	ELAC2;ELAC1	high;moderate	NA	NA	NA	"The gene Juvenile hormone-inducible protein 1 is referred to in FlyBase by the symbol Dmel\JhI-1 (CG3298, FBgn0028426). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:10307030..10309794. It has the cytological map location 47A1. Protein features are: Metallo-beta-lactamase; tRNase Z endonuclease. Its molecular function is described by: endoribonuclease activity, producing 5'-phosphomonoesters; 3'-tRNA processing endoribonuclease activity. It is involved in the biological process described with: positive regulation of cell growth; positive regulation of translation; ventral cord development; regulation of cell growth; mitochondrial tRNA 3'-trailer cleavage, endonucleolytic; tRNA splicing, via endonucleolytic cleavage and ligation; nuclear tRNA 3'-trailer cleavage, endonucleolytic; germ cell proliferation; tRNA 3'-trailer cleavage, endonucleolytic; tRNA 3'-end processing. 20 alleles are reported. The phenotypes of these alleles manifest in: imaginal precursor; eye-antennal disc; intracellular membrane-bounded organelle; embryonic/larval imaginal precursor; intracellular part; somatic precursor cell; developing material anatomical entity; cell; adult external head; sclerite. The phenotypic classes of alleles include: phenotype; lethal - all die before end of larval stage; increased mortality; sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0034523	Nnf1a	0.391846851	0.321689287	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Nnf1a is referred to in FlyBase by the symbol Dmel\Nnf1a (CG13434, FBgn0034523). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:20586222..20587238. It has the cytological map location 57A6. Its molecular function is unknown. It is involved in the biological process described with: chromosome segregation; mitotic metaphase plate congression. 6 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum. The phenotypic classes of alleles include: visible; viable; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0043575	PGRP-SC2	0.392273884	0.250340378	0.999936032	NA	PGLYRP1;PGLYRP4;PGLYRP3;PGLYRP2	high;moderate;low;low	NA	transmembrane protein	NA	"The gene Peptidoglycan recognition protein SC2 is referred to in FlyBase by the symbol Dmel\PGRP-SC2 (CG14745, FBgn0043575). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:8716950..8717695. It has the cytological map location 44E2. Protein features are: N-acetylmuramoyl-L-alanine amidase domain; Peptidoglycan recognition protein; Peptidoglycan recognition protein family domain, metazoa/bacteria; Peptidoglycan recognition protein, PGRP-S. Its molecular function is described by: peptidoglycan binding; N-acetylmuramoyl-L-alanine amidase activity; zinc ion binding. It is involved in the biological process described with: immune response; peptidoglycan catabolic process; negative regulation of innate immune response. 7 alleles are reported. The phenotype of these alleles manifest in: intestinal stem cell. The phenotypic classes of alleles include: viable; long lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late larval stages, in stages of adults of both sexes.  "
FBgn0034249	RhoGAP54D	0.39228897	0.349160178	0.999936032	ARHGAP19	ARHGAP19	high	NA	NA	NA	"The gene Rho GTPase activating protein at 54D is referred to in FlyBase by the symbol Dmel\RhoGAP54D (CG6477, FBgn0034249). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:17586425..17590884. It has the cytological map location 54C11-54C12. Protein features are: Rho GTPase activation protein; Rho GTPase-activating protein domain. Its molecular function is described by: GTPase activator activity. It is involved in the biological process described with: small GTPase mediated signal transduction; imaginal disc-derived leg morphogenesis. 10 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0001075	ft	0.392597606	0.325011839	0.999936032	NA	FAT4;FAT3;CDH23;FAT1;DCHS2;DCHS1;FAT2	high;low;low;low;low;low;low	Maybe TF	transmembrane protein	NA	"The gene fat is referred to in FlyBase by the symbol Dmel\ft (CG3352, FBgn0001075). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:4198404..4221796. It has the cytological map location 24D8. Protein features are: Cadherin; Cadherin conserved site; Cadherin-like; Catenin binding domain; Concanavalin A-like lectin/glucanase domain; EGF-like calcium-binding domain; EGF-like domain; EGF-like, conserved site; Laminin G domain. Its molecular function is described by: calcium ion binding; cadherin binding; receptor activity; protein binding; cell adhesion molecule binding. It is involved in the biological process described with 37 unique terms, many of which group under: biological adhesion; cell adhesion; organic substance metabolic process; cell proliferation; macromolecule metabolic process; regulation of growth; cell-cell adhesion; imaginal disc pattern formation; cell projection organization; equator specification; single organismal cell-cell adhesion; cellular macromolecule localization; microtubule cytoskeleton organization. 127 alleles are reported. The phenotypes of these alleles manifest in: intracellular part; cell; brain; anatomical space; stem cell; eye-antennal disc; intracellular non-membrane-bounded organelle; interommatidial bristle; alimentary canal; abdominal tergite marginal bristle; supramolecular polymer; intracellular membrane-bounded organelle; larval prothoracic segment. The phenotypic classes of alleles include: size defective; lethal - all die before end of P-stage; phenotype; cell cycle defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0259113	DNApol-alpha180	0.392597606	0.325011839	0.999936032	NA	POLA1	high	NA	NA	NA	"The gene DNA polymerase ‘± 180kD is referred to in FlyBase by the symbol Dmel\DNApol-‘±180 (CG6349, FBgn0259113). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:21666562..21671750. It has the cytological map location 93F2. Protein features are: DNA polymerase alpha catalytic subunit; DNA polymerase alpha catalytic subunit, N-terminal domain; DNA polymerase, palm domain; DNA-directed DNA polymerase, family B; DNA-directed DNA polymerase, family B, conserved site; DNA-directed DNA polymerase, family B, exonuclease domain; DNA-directed DNA polymerase, family B, multifunctional domain; Ribonuclease H-like domain; Zinc finger, DNA-directed DNA polymerase, family B, alpha. Its molecular function is described by: nucleotide binding; 3'-5' exonuclease activity; DNA binding; DNA-directed DNA polymerase activity; nucleoside binding. It is involved in the biological process described with: double-strand break repair via nonhomologous end joining; leading strand elongation; lagging strand elongation; DNA replication; DNA replication initiation. 10 alleles are reported. The phenotypes of these alleles manifest in: eye; embryonic/larval neuroblast; ganglion mother cell. The phenotypic classes of alleles include: increased mortality during development; phenotype; lethal; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0001128	Gpdh	0.392705069	0.250153143	0.999936032	GPD1	GPD1;GPD1L	high;moderate	NA	NA	NA	"The gene Glycerol 3 phosphate dehydrogenase is referred to in FlyBase by the symbol Dmel\Gpdh (CG9042, FBgn0001128). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (3 unique). Gene sequence location is 2L:5943643..5948968. It has the cytological map location 26A3. Protein features are: 6-phosphogluconate dehydrogenase C-terminal domain-like; 6-phosphogluconate dehydrogenase, domain 2; Glycerol-3-phosphate dehydrogenase, NAD-dependent; Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal; Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal; Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic; NAD(P)-binding domain. Its molecular function is described by: protein homodimerization activity; glycerol-3-phosphate dehydrogenase [NAD+] activity; NAD binding. It is involved in the biological process described with: carbohydrate metabolic process; glycerol-3-phosphate catabolic process; response to hyperoxia; oxidation-reduction process; flight behavior; triglyceride metabolic process; ethanol metabolic process. 147 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval hemocyte. The phenotypic classes of alleles include: flight defective; phenotype; lethal - all die before end of prepupal stage; stress response defective; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0267252	Ggamma30A	0.392790492	0.33393069	0.999936032	NA	GNG13;GNG8;GNG12;GNG11;GNG3;GNG10;GNGT1;GNG7;GNG4;GNG5	high;moderate;low;low;low;low;low;low;low;low	NA	NA	NA	"The gene G protein subunit ‘_ at 30A is referred to in FlyBase by the symbol Dmel\G‘_30A (CG3694, FBgn0267252). It is a protein_coding_gene from Drosophila melanogaster. It has 8 annotated transcripts and 8 polypeptides (3 unique). Gene sequence location is 2L:9256563..9302494. It has the cytological map location 30A6-30A7. Protein features are: G-protein gamma-like domain; G-protein, gamma subunit. Its molecular function is described by: protein heterodimerization activity; signal transducer activity. It is involved in the biological process described with: cellular response to carbon dioxide; phototransduction; regulation of glucose metabolic process; G-protein coupled receptor signaling pathway. 13 alleles are reported. The phenotype of these alleles manifest in: adult olfactory receptor neuron Gr21a/63a. The phenotypic classes of alleles include: fertile; neurophysiology defective; viable; sensory perception defective."
FBgn0037506	Mics1	0.392848811	0.263699339	0.999936032	NA	GHITM	moderate	NA	transmembrane protein	NA	"The gene Mitochondrial morphology and cristae structure 1 is referred to in FlyBase by the symbol Dmel\Mics1 (CG1287, FBgn0037506). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:7500951..7502376. It has the cytological map location 84D9. Protein features are: Bax inhibitor 1-related. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: body size defective; developmental rate defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed in adult male stages.  "
FBgn0000463	Dl	0.393216703	0.349227631	0.999936032	NA	DLL1;DLL4;DLL3	high;moderate;moderate	NA	transmembrane protein	NA	"The gene Delta is referred to in FlyBase by the symbol Dmel\Dl (CG3619, FBgn0000463). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:19302731..19326217. It has the cytological map location 92A1-92A2. Protein features are: Delta/Serrate/lag-2 (DSL) protein; EGF-like calcium-binding domain; EGF-like calcium-binding, conserved site; EGF-like domain; EGF-like, conserved site; EGF-type aspartate/asparagine hydroxylation site; Growth factor receptor cysteine-rich domain; Notch ligand, N-terminal domain. Its molecular function is described by: Notch binding; protein binding; calcium ion binding; receptor binding. It is involved in the biological process described with 49 unique terms, many of which group under: cell communication; peripheral nervous system development; negative regulation of nervous system development; ventral cord development; signal transduction; actin cytoskeleton organization; germ-line stem cell population maintenance; biological adhesion; regulation of biological quality; positive regulation of biological process. 436 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval somatic muscle; abdomen; single-organism process; cuboidal/columnar epithelium; dorsal cluster neuron; head mesoderm derived embryonic hemocyte; tracheal branch primordium; hub cell; filzkorper; surface associated glial cell; retrocerebral complex; rhabdomere; embryonic/larval dorsal branch; embryonic/larval dorsal vessel. The phenotypic classes of alleles include: long lived; wild-type; some die during pupal stage; neuroanatomy defective; cell number defective; partially lethal - majority die; lethal - all die before end of first instar larval stage; phenotype; increased mortality; body color defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0027508	Tnks	0.39332607	0.32499076	0.999936032	NA	TNKS;TNKS2	high;moderate	NA	NA	NA	"The gene tankyrase is referred to in FlyBase by the symbol Dmel\Tnks (CG4719, FBgn0027508). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:25653091..25661286. It has the cytological map location 96E7-96E8. Protein features are: Ankyrin repeat; Ankyrin repeat-containing domain; Poly(ADP-ribose) polymerase, catalytic domain; Sterile alpha motif domain; Sterile alpha motif/pointed domain; Tankyrase-1; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: scaffold protein binding; NAD+ ADP-ribosyltransferase activity. It is involved in the biological process described with: canonical Wnt signaling pathway; wing disc development; spindle assembly; positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; chaeta development; positive regulation of telomere maintenance via telomerase; protein ADP-ribosylation; protein poly-ADP-ribosylation; positive regulation of proteolysis; regulation of proteasome assembly. 17 alleles are reported. The phenotypes of these alleles manifest in: enteroblast; adult midgut; intestinal stem cell. The phenotypic classes of alleles include: viable; fertile; short lived; increased cell number. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during late pupal stages.  "
FBgn0086695	hd	0.394496969	0.332337975	0.999936032	NA	DONSON	high	NA	NA	NA	"The gene humpty dumpty is referred to in FlyBase by the symbol Dmel\hd (CG2669, FBgn0086695). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:5372592..5374962. It has the cytological map location 83A1. Protein features are: Donson. Its molecular function is described by: . It is involved in the biological process described with: eggshell chorion gene amplification; cell proliferation; nuclear DNA replication. 9 alleles are reported. The phenotypes of these alleles manifest in: follicle cell; endochorion; polytene chromosome; chorion; embryonic/larval brain; imaginal disc. The phenotypic classes of alleles include: lethal; increased mortality; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0010215	alpha-Cat	0.394788578	0.287536374	0.999936032	CTNNA2	CTNNA2;CTNNA1;CTNNA3	high;moderate;moderate	NA	NA	NA	"The gene ‘± Catenin is referred to in FlyBase by the symbol Dmel\‘±-Cat (CG17947, FBgn0010215). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:23318646..23338100. It has the cytological map location 80F1-80F2. Protein features are: Alpha-catenin; Vinculin, conserved site; Vinculin/alpha-catenin. Its molecular function is described by: actin binding; cytoskeletal protein binding; actin filament binding; protein binding; structural molecule activity; cadherin binding. It is involved in the biological process described with: establishment or maintenance of cell polarity; epithelium development; cell adhesion; cytoskeletal anchoring at plasma membrane; germarium-derived egg chamber formation; head morphogenesis; apical constriction; adherens junction organization; dorsal closure, amnioserosa morphology change; adherens junction assembly. 42 alleles are reported. The phenotypes of these alleles manifest in: cuticle; apoptotic amnioserosa; amnioserosa; anchoring junction; adult head sensillum; prepupa; supramolecular polymer; adherens junction; extended germ band embryo; retinal pigment cell; adult sensillum. The phenotypic classes of alleles include: phenotype; cell lethal; increased mortality; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, during early pupal stages.  "
FBgn0037721	CG9427	0.394953875	0.273968834	0.999936032	NA	IFI30	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9427 (FBgn0037721). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:9625157..9626930. It has the cytological map location 85E1. Protein features are: Gamma interferon inducible lysosomal thiol reductase GILT; Thioredoxin-like fold. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during pupal stage; lethal - all die before end of pupal stage; viable; flightless. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the larval period, at stages throughout the pupal period.  "
FBgn0024542	Neos	0.395091395	0.318615822	0.999936032	NA	NCOA5	high	NA	NA	NA	"The gene Neosin is referred to in FlyBase by the symbol Dmel\Neos (CG8614, FBgn0024542). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:7241628..7243139. It has the cytological map location 65E9. Protein features are: Anticodon-binding; RNA recognition motif domain. Its molecular function is described by: nucleic acid binding; mRNA binding. It is involved in the biological process described with: mRNA splicing, via spliceosome. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; female semi-sterile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0032734	CG15169	0.395955512	0.227270156	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG15169 (FBgn0032734). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:18991020..18992409. It has the cytological map location 37B8. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed during early pupal stages.
FBgn0037082	CG5664	0.396150487	0.345566811	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5664 (FBgn0037082). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:21438628..21441363. It has the cytological map location 78D2. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0033356	CG8229	0.39620513	0.329793041	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8229 (FBgn0033356). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:8948113..8951086. It has the cytological map location 44F11. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0033787	CG13321	0.396489655	0.243936349	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13321 (FBgn0033787). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:12953112..12955712. It has the cytological map location 49E4. Protein features are: DM9 repeat; Domain of unknown function DUF3421. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; embryonic/larval neuroblast. The phenotypic classes of alleles include: neuroanatomy defective; lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, in adult female stages.  "
FBgn0011722	Tig	0.39670308	0.252424814	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Tiggrin is referred to in FlyBase by the symbol Dmel\Tig (CG11527, FBgn0011722). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:6415179..6423310. It has the cytological map location 26D1. Protein features are: Haem oxygenase-like, multi-helical. Its molecular function is described by: integrin binding. It is involved in the biological process described with: photoreceptor cell axon guidance; cell-substrate adhesion; regulation of cell adhesion mediated by integrin; cell adhesion mediated by integrin; substrate adhesion-dependent cell spreading; phagocytosis; axon guidance. 11 alleles are reported. The phenotypes of these alleles manifest in: pupa; cell; eye photoreceptor cell; abdominal 5 segment border muscle; adult abdomen; neuron projection; neuron projection bundle; cell part; integumentary system; photoreceptor cell. The phenotypic classes of alleles include: viable; some die during pupal stage; lethal - all die before end of pupal stage; partially lethal - majority die; locomotor behavior defective; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages.  "
FBgn0041182	Tep2	0.396866791	0.344763522	0.999936032	NA	CD109;C3;C4B;C4A;A2ML1;C5	high;low;moderate;low;low;low	NA	transmembrane protein	NA	"The gene Thioester-containing protein 2 is referred to in FlyBase by the symbol Dmel\Tep2 (CG7052, FBgn0041182). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (all unique). Gene sequence location is 2L:7693727..7701601. It has the cytological map location 28C1. Protein features are: Alpha-2-macroglobulin; Alpha-2-macroglobulin, N-terminal; Alpha-2-macroglobulin, N-terminal 2; Alpha-2-macroglobulin, conserved site; Alpha-2-macroglobulin, thiol-ester bond-forming; Alpha-macroglobulin complement component; Alpha-macroglobulin, receptor-binding; Immunoglobulin-like fold; Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid. Its molecular function is described by: endopeptidase inhibitor activity. It is involved in the biological process described with: phagocytosis; defense response to Gram-negative bacterium. 12 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during late larval stages, at stages throughout the pupal period.  "
FBgn0004574	Rop	0.397174298	0.25502162	0.999936032	NA	STXBP1;STXBP2;STXBP3	high;moderate;moderate	NA	NA	NA	"The gene Ras opposite is referred to in FlyBase by the symbol Dmel\Rop (CG15811, FBgn0004574). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:4136359..4138996. It has the cytological map location 64A7. Protein features are: Sec1-like protein. Its molecular function is described by: SNARE binding. It is involved in the biological process described with 13 unique terms, many of which group under: transport; developmental maturation; positive regulation of neurogenesis; response to stimulus; cytokinesis; response to abiotic stimulus; signal release; exocytosis; regulation of reproductive process; response to light stimulus. 25 alleles are reported. The phenotypes of these alleles manifest in: central nervous system; oocyte; class IV dendritic arborizing neuron; embryonic/first instar larval cuticle; egg; tracheal branch primordium; class I dendritic arborizing neuron. The phenotypic classes of alleles include: increased mortality; lethal; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0264006	dysc	0.397285056	0.339420348	0.999936032	NA	WHRN;PDZD7	high;moderate	NA	NA	NA	"The gene dyschronic is referred to in FlyBase by the symbol Dmel\dysc (CG43749, FBgn0264006). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (all unique). Gene sequence location is 3L:13867414..13903236. It has the cytological map location 70C5. Protein features are: PDZ domain; Whirlin. Its molecular function is described by: . It is involved in the biological process described with: regulation of synaptic growth at neuromuscular junction; sensory perception of light stimulus; photoreceptor cell axon guidance; sensory perception of sound; muscle cell cellular homeostasis; negative regulation of neuromuscular synaptic transmission; positive regulation of ion transmembrane transporter activity; rhabdomere development; locomotor rhythm. 28 alleles are reported. The phenotypes of these alleles manifest in: lamina plexus; NMJ bouton; type Ib terminal bouton; indirect flight muscle; rhabdomere; axon; type Is terminal bouton. The phenotypic classes of alleles include: stress response defective; increased mortality; phenotype; behavior defective."
FBgn0266918	CG32486	0.397312249	0.272097872	0.999936032	NA	CYHR1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32486 (FBgn0266918). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:3055908..3070839. It has the cytological map location 63A4-63A6. Protein features are: TRAF-like; Zinc finger, RING-type; Zinc finger, RING/FYVE/PHD-type; Zinc finger, TRAF-type. Its molecular function is described by: zinc ion binding. The biological processes in which it is involved are not known. 8 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum. The phenotypic classes of alleles include: visible; viable; lethal - all die during P-stage; lethal; some die during pupal stage; partially lethal - majority die."
FBgn0030345	CG1847	0.398011459	0.288114801	0.999936032	AIP	AIP;AIPL1	high;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1847 (FBgn0030345). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:11869170..11871168. It has the cytological map location 10F2. Protein features are: FKBP-type peptidyl-prolyl cis-trans isomerase domain; Tetratricopeptide repeat; Tetratricopeptide repeat-containing domain; Tetratricopeptide-like helical domain. Its molecular function is unknown. It is involved in the biological process described with: sensory perception of pain. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: pain response defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, in adult female stages.  "
FBgn0042112	mRpL36	0.398094266	0.276265246	0.999936032	NA	MRPL36	high	NA	NA	NA	"The gene mitochondrial ribosomal protein L36 is referred to in FlyBase by the symbol Dmel\mRpL36 (CG18767, FBgn0042112). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:8124584..8125132. It has the cytological map location 66B7. Protein features are: Ribosomal protein L36. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation. 4 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; Z disc; sarcomere; mesothoracic tergum. The phenotypic classes of alleles include: visible; viable; lethal - all die during larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 06-12 hour embryonic stages, during early larval stages.  "
FBgn0038640	CG7706	0.39836217	0.335977416	0.999936032	SLC4A1AP	SLC4A1AP	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG7706 (FBgn0038640). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:18677818..18680321. It has the cytological map location 91C1. Protein features are: Forkhead-associated (FHA) domain; SMAD/FHA domain. Its molecular function is described by: mRNA binding. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0039862	kek6	0.398412048	0.203030409	0.999936032	NA	LRRC24;LRTM2	moderate;high	NA	transmembrane protein	NA	"The gene kek6 is referred to in FlyBase by the symbol Dmel\kek6 (CG1804, FBgn0039862). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:31622136..31664646. It has the cytological map location 100D1. Protein features are: Cysteine-rich flanking region, C-terminal; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold; Leucine-rich repeat; Leucine-rich repeat domain, L domain-like; Leucine-rich repeat, typical subtype. Its molecular function is unknown. It is involved in the biological process described with: lateral inhibition. 11 alleles are reported. The phenotypes of these alleles manifest in: chaeta; mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: increased mortality; some die during P-stage; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period.  "
FBgn0042696	NfI	0.398660256	0.296758492	0.999936032	NA	NFIA;NFIC;NFIB;NFIX	high;moderate;moderate;moderate	DNA-binding with transcription factor activity(MH1)	NA	NA	"The gene Nuclear factor I is referred to in FlyBase by the symbol Dmel\NfI (CG2380, FBgn0042696). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 4:268175..276369. It has the cytological map location 102B1-102B2. Protein features are: CTF transcription factor/nuclear factor 1; CTF transcription factor/nuclear factor 1, DNA-binding domain; CTF transcription factor/nuclear factor 1, N-terminal; MAD homology 1, Dwarfin-type. Its molecular function is described by: RNA polymerase II transcription factor activity, sequence-specific DNA binding. It is involved in the biological process described with: DNA replication; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0050496	CG30496	0.398880783	0.334073374	0.999936032	NA	GLMN	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG30496 (FBgn0050496). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:7699500..7701878. It has the cytological map location 43E11. Protein features are: Armadillo-like helical; Glomulin/ALF4; YAP-binding/ALF4/Glomulin. Its molecular function is described by: ubiquitin-protein transferase inhibitor activity; ubiquitin protein ligase binding. It is involved in the biological process described with: negative regulation of protein ubiquitination. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0030699	CG8578	0.398987389	0.284554975	0.999936032	NA	LRRFIP2;LRRFIP1	high;moderate	DNA-binding with transcription factor activity	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8578 (FBgn0030699). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is X:15844476..15847858. It has the cytological map location 13F10-13F12. Protein features are: Leucine-rich repeat flightless-interacting protein 1/2. Its molecular function is described by: Rab GTPase binding. It is involved in the biological process described with: adult somatic muscle development; regulation of transcription, DNA-templated. 5 alleles are reported. The phenotypes of these alleles manifest in: indirect flight muscle; myofibril; sarcomere. The phenotypic classes of alleles include: viable; flightless; partially lethal; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0030970	CG7326	0.399135357	0.313301591	0.999936032	NA	UBE3D	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG7326 (FBgn0030970). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:18861197..18863776. It has the cytological map location 17F1. Protein features are: Ubiquitin-conjugating enzyme E2-binding protein. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0034572	CG9346	0.39973039	0.325141749	0.999936032	U2SURP	U2SURP	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9346 (FBgn0034572). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:21011970..21015628. It has the cytological map location 57B9. Protein features are: CID domain; ENTH/VHS; RNA recognition motif domain; SR140, RNA recognition motif; SWAP/Surp; mRNA splicing factor Cwf21 domain. Its molecular function is described by: mRNA binding; RNA binding. It is involved in the biological process described with: RNA processing. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: flightless; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages.  "
FBgn0262117	IntS3	0.399991461	0.302240753	0.999936032	NA	INTS3	high	NA	NA	NA	"The gene Integrator 3 is referred to in FlyBase by the symbol Dmel\IntS3 (CG17665, FBgn0262117). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:4235779..4242934. It has the cytological map location h44-h46. Protein features are: Integrator complex subunit 3. Its molecular function is described by: . It is involved in the biological process described with: snRNA processing. 13 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; wing. The phenotypic classes of alleles include: visible; viable; lethal; partially lethal - majority die."
FBgn0015546	spel1	0.400100053	0.340934	0.999936032	MSH2	MSH2	high	NA	NA	NA	"The gene spellchecker1 is referred to in FlyBase by the symbol Dmel\spel1 (CG4215, FBgn0015546). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2L:14362069..14366840. It has the cytological map location 35A4-35B1. Protein features are: DNA mismatch repair Msh2-type; DNA mismatch repair protein Msh2; DNA mismatch repair protein MutS, C-terminal; DNA mismatch repair protein MutS, N-terminal; DNA mismatch repair protein MutS, clamp; DNA mismatch repair protein MutS, connector domain; DNA mismatch repair protein MutS, core; DNA mismatch repair protein MutS-like, N-terminal; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: four-way junction DNA binding; ATP binding; Y-form DNA binding; heteroduplex DNA loop binding; damaged DNA binding; DNA-dependent ATPase activity; single base insertion or deletion binding; double-strand/single-strand DNA junction binding; guanine/thymine mispair binding; DNA binding. It is involved in the biological process described with 11 unique terms, many of which group under: response to radiation; response to abiotic stimulus; signal transduction by p53 class mediator; response to UV-B; reciprocal meiotic recombination; interstrand cross-link repair; mitotic cell cycle; signaling; regulation of cellular component organization; maintenance of DNA repeat elements; postreplication repair; response to UV; regulation of mitotic cell cycle. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0051514	CR31514	0.400306254	0.240918718	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR31514 (FBgn0051514). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3R:9779519..9782693. It has the cytological map location 85E8. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0259192	CG42296	0.400752987	0.273040074	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG42296 (FBgn0259192). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:2032519..2036041. It has the cytological map location 22C1. Protein features are: Chitin binding domain. Its molecular function is described by: chitin binding; chitinase activity. It is involved in the biological process described with: chitin catabolic process. 3 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-18 embryonic stages.
FBgn0262109	CR42862	0.400929109	0.246842806	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR42862 (FBgn0262109). It is a non_protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts. Gene sequence location is 3L:224106..230964. It has the cytological map location 61B2. Its molecular function is described by: . It is involved in the biological process described with: . 13 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable.
FBgn0035229	pns	0.401020687	0.336756981	0.999936032	NA	DENND5B;DENND5A	high;high	NA	NA	NA	"The gene pinstripe is referred to in FlyBase by the symbol Dmel\pns (CG7852, FBgn0035229). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:1537137..1544823. It has the cytological map location 62A3. Protein features are: DENN domain; PLAT/LH2 domain; RUN domain; dDENN domain; uDENN domain. Its molecular function is described by: Rab guanyl-nucleotide exchange factor activity; calcium channel activity. It is involved in the biological process described with: detection of mechanical stimulus; regulation of Rab protein signal transduction; adult chitin-containing cuticle pigmentation. 5 alleles are reported. The phenotypes of these alleles manifest in: abdominal tergite 5; abdominal tergite 6. The phenotypic classes of alleles include: lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0051875	CG31875	0.401877881	0.314758244	0.999936032	NA	RCOR1;RCOR2;RCOR3	moderate;low;low	DNA-binding with transcription factor activity(SANT)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31875 (FBgn0051875). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2L:9995561..10002736. It has the cytological map location 30F5. Protein features are: ELM2 domain. Its molecular function is described by: transcription corepressor activity; transcription factor binding; transcription factor activity, sequence-specific DNA binding; transcription regulatory region DNA binding. It is involved in the biological process described with: negative regulation of transcription from RNA polymerase II promoter. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0267339	p38c	0.402506162	0.27114303	0.999936032	NA	MAPK11;MAPK14;MAPK13;MAPK12;MAPK15;MAPK7;MAPK1;MAPK3	moderate;moderate;moderate;moderate;low;low;low;low	NA	NA	NA	"The gene p38c MAP kinase is referred to in FlyBase by the symbol Dmel\p38c (CG33338, FBgn0267339). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:24149020..24150203. It has the cytological map location 95D7-95F15. Protein features are: Mitogen-activated protein (MAP) kinase, conserved site; Protein kinase domain; Protein kinase, ATP binding site; Protein kinase-like domain. Its molecular function is described by: ATP binding; MAP kinase activity. It is involved in the biological process described with: regulation of gene expression; regulation of adult chitin-containing cuticle pigmentation; protein phosphorylation; response to bacterium; regulation of lipid storage; regulation of response to oxidative stress. 14 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: male fertile; immune response defective; female fertile; oxidative stress response defective; female sterile."
FBgn0035888	CG7120	0.402990368	0.252882381	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7120 (FBgn0035888). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3L:8396000..8402295. It has the cytological map location 66C11. Protein features are: Alkaline phosphatase-like, alpha/beta/alpha; Alkaline-phosphatase-like, core domain; Protein of unknown function DUF229. Its molecular function is described by: catalytic activity. It is involved in the biological process described with: metabolic process; multicellular organism reproduction. 5 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: fertile; viable; visible; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0034438	CG9416	0.403044924	0.328651696	0.999936032	ERMP1	ERMP1	high	Maybe TF	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9416 (FBgn0034438). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:19367248..19373702. It has the cytological map location 56D2. Protein features are: Peptidase M28. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 06-18 hour embryonic stages, during late pupal stages.  "
FBgn0032889	CG9331	0.403159845	0.238284129	0.999936032	NA	GRHPR	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9331 (FBgn0032889). It is a protein_coding_gene from Drosophila melanogaster. It has 12 annotated transcripts and 12 polypeptides (3 unique). Gene sequence location is 2L:20822828..20827744. It has the cytological map location 38F1. Protein features are: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; NAD(P)-binding domain. Its molecular function is described by: glyoxylate reductase (NADP) activity; NAD binding; hydroxypyruvate reductase activity. It is involved in the biological process described with: oxidation-reduction process. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: locomotor behavior defective; viable; fertile; short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, in adult male stages.  "
FBgn0031412	CG16995	0.403499343	0.295526504	0.999936032	NA	GLIPR2;PI16;CRISPLD2;CRISPLD1	moderate;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG16995 (FBgn0031412). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:2307948..2308872. It has the cytological map location 22E1. Protein features are: Allergen V5/Tpx-1-related, conserved site; CAP domain; Cysteine-rich  secretory protein, allergen V5/Tpx-1-related; Golgi-associated plant pathogenesis-related protein 1, SCP domain. Its molecular function is described by: . It is involved in the biological process described with: multicellular organism reproduction. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0013683	mt:ND4L	0.403608272	0.271011415	0.999936032	NA	ND4L	high	NA	transmembrane protein	NA	"The gene mitochondrial NADH-ubiquinone oxidoreductase chain 4L is referred to in FlyBase by the symbol Dmel\mt:ND4L (CG34086, FBgn0013683). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is mitochondrion_genome:9545..9835. Protein features are: NADH-ubiquinone oxidoreductase chain 4L/K. Its molecular function is described by: NADH dehydrogenase (ubiquinone) activity. It is involved in the biological process described with: ATP synthesis coupled electron transport. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very low expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0030887	CG6867	0.403684948	0.327662244	0.999936032	NA	GLDN;OLFML2A;MYOC;OLFM1;OLFML1;OLFML3;OLFML2B;OLFM2;OLFM4;OLFM3;IGLON5;LSAMP;NTM;NEGR1;OPCML;ADGRL1;ADGRL2	high;high;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;low;low;low;low;low;low;low	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG6867 (FBgn0030887). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:18023870..18028261. It has the cytological map location 16F5. Protein features are: Collagen triple helix repeat; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold; Olfactomedin-like domain. Its molecular function is unknown. It is involved in the biological process described with: motor neuron axon guidance; synaptic target inhibition. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-18 embryonic stages.
FBgn0014007	Ptp69D	0.403998849	0.32364816	0.999936032	NA	PTPRC;PTPRZ1;PTPRA;PTPRE	high;low;moderate;moderate	NA	transmembrane protein	NA	"The gene Protein tyrosine phosphatase 69D is referred to in FlyBase by the symbol Dmel\Ptp69D (CG10975, FBgn0014007). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:12734945..12741568. It has the cytological map location 69D6-69E1. Protein features are: Fibronectin type III; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold; PTP type protein phosphatase; Protein-tyrosine phosphatase, active site; Protein-tyrosine phosphatase, catalytic; Protein-tyrosine phosphatase-like; Tyrosine specific protein phosphatases domain. Its molecular function is described by: transmembrane receptor protein tyrosine phosphatase activity. It is involved in the biological process described with: fasciculation of sensory neuron axon; defasciculation of motor neuron axon; peptidyl-tyrosine dephosphorylation; axon guidance; dendrite morphogenesis; motor neuron axon guidance; lateral inhibition. 59 alleles are reported. The phenotypes of these alleles manifest in: dendritic arborizing neuron; mesothoracic tergum; medulla; axon; chaeta; dendrite; abdominal segmental nerve; central nervous system; lamina plexus; intersegmental nerve. The phenotypic classes of alleles include: phenotype; increased mortality during development; visible; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during early pupal stages, in adult female stages.  "
FBgn0262954	Rpb12	0.404254248	0.258461197	0.999936032	NA	POLR2K	high	NA	NA	NA	"The gene Rpb12 is referred to in FlyBase by the symbol Dmel\Rpb12 (CG34186, FBgn0262954). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:15144968..15145519. It has the cytological map location 51E2. Protein features are: RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4; RNA polymerase subunit RPABC4/transcription elongation factor Spt4. Its molecular function is described by: RNA polymerase III activity; RNA polymerase II activity; DNA-directed 5'-3' RNA polymerase activity; RNA polymerase I activity; DNA binding. It is involved in the biological process described with: transcription from RNA polymerase II promoter. No alleles are reported."
FBgn0022943	Cbp20	0.404444079	0.265917059	0.999936032	NA	NCBP2;NCBP2L	high;moderate	NA	NA	NA	"The gene cap binding protein 20 is referred to in FlyBase by the symbol Dmel\Cbp20 (CG12357, FBgn0022943). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:18164661..18165439. It has the cytological map location 90F4. Protein features are: NCBP2, RNA recognition motif; Nuclear cap-binding protein subunit 2; RNA recognition motif domain. Its molecular function is described by: RNA cap binding; protein binding; mRNA binding. It is involved in the biological process described with: negative regulation of viral genome replication; production of siRNA involved in RNA interference; mRNA cis splicing, via spliceosome; RNA interference; mRNA splicing, via spliceosome; gene silencing by miRNA; primary miRNA processing. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during pupal stage; lethal - all die before end of pupal stage; viable; female sterile; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0026722	drosha	0.404782608	0.318934121	0.999936032	DROSHA	DROSHA	high	NA	NA	NA	"The gene drosha is referred to in FlyBase by the symbol Dmel\drosha (CG8730, FBgn0026722). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:7932429..7936840. It has the cytological map location 43F2-43F3. Protein features are: Double-stranded RNA-binding domain; Ribonuclease III; Ribonuclease III domain. Its molecular function is described by: double-stranded RNA binding; ribonuclease III activity. It is involved in the biological process described with: primary miRNA processing; germarium-derived oocyte fate determination; germarium-derived female germ-line cyst formation; salivary gland histolysis; RNA phosphodiester bond hydrolysis, endonucleolytic; mushroom body development; pre-miRNA processing; production of siRNA involved in RNA interference; cellular response to starvation; rRNA catabolic process. 22 alleles are reported. The phenotypes of these alleles manifest in: adult ALad1 lineage clone; gland; compound sense organ; cell cluster organ; mushroom body medial lobe; foregut; mushroom body gamma-lobe; eye; trichogen cell; wing. The phenotypic classes of alleles include: lethal; neurophysiology defective; visible; viable; neuroanatomy defective; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0029826	CG6041	0.405350467	0.239191979	0.999936032	NA	KLK10;AZU1;CFD;PRSS55	low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6041 (FBgn0029826). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:5948160..5950208. It has the cytological map location 5C10. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during late larval stages.  "
FBgn0052698	CG32698	0.405916068	0.311221291	0.999936032	NA	CA10;CA11	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32698 (FBgn0052698). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is X:9783223..9855449. It has the cytological map location 9A1-9A2. Protein features are: Alpha carbonic anhydrase; Carbonic anhydrase, alpha-class. Its molecular function is unknown. It is involved in the biological process described with: sensory perception of pain. 14 alleles are reported. The phenotypes of these alleles manifest in: sarcomere; Z disc. The phenotypic classes of alleles include: lethal; fertile; viable; some die during embryonic stage; partially lethal; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during late larval stages, at stages throughout the pupal period.  "
FBgn0027101	Dyrk3	0.406099158	0.276307451	0.999936032	NA	DYRK2;DYRK3;DYRK4;DYRK1B;DYRK1A;HIPK2;HIPK1;HIPK3	high;moderate;low;low;low;low;low;low	NA	NA	NA	"The gene Dual-specificity tyrosine phosphorylation-regulated kinase 3 is referred to in FlyBase by the symbol Dmel\Dyrk3 (CG40478, FBgn0027101). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 4:1225089..1230713. It has the cytological map location 102F8. Protein features are: Protein kinase domain; Protein kinase, ATP binding site; Protein kinase-like domain; Serine/threonine-protein kinase, active site. Its molecular function is described by: ATP binding; protein kinase activity. It is involved in the biological process described with: protein phosphorylation. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; female semi-sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0263232	Nxf3	0.406357936	0.333559884	0.999936032	NA	NXF1;NXF3;NXF5;NXF2B;NXF2	moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"The gene Nuclear export factor 3 is referred to in FlyBase by the symbol Dmel\Nxf3 (CG32135, FBgn0263232). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:13965203..13973067. It has the cytological map location 70C7-70C9. Protein features are: Leucine-rich repeat; Leucine-rich repeat domain, L domain-like; NTF2-like domain; Nuclear RNA export factor; Nuclear transport factor 2; Nuclear transport factor 2, eukaryote. Its molecular function is described by: RNA binding. It is involved in the biological process described with: poly(A)+ mRNA export from nucleus. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: female fertile; viable; female semi-sterile."
FBgn0034480	CG16898	0.406382386	0.259882651	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG16898 (FBgn0034480). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:20003620..20005003. It has the cytological map location 56F4. Protein features are: CHK kinase-like; Protein kinase-like domain; Protein of unknown function DUF227. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed during late pupal stages.
FBgn0033236	CG14764	0.407482228	0.278360082	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14764 (FBgn0033236). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2R:7942043..7955882. It has the cytological map location 43F4-43F7. Its molecular function is unknown. The biological processes in which it is involved are not known. 12 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0261929	5-HT2B	0.407771108	0.205863733	0.999936032	NA	HRH3;HRH4;HTR2C;HTR2A;HTR2B	low;low;low;low;low	NA	transmembrane protein	GPCR	"The gene 5-hydroxytryptamine (serotonin) receptor 2B is referred to in FlyBase by the symbol Dmel\5-HT2B (CG42796, FBgn0261929). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:8578205..8629996. It has the cytological map location 85A3-85A5. Protein features are: G protein-coupled receptor, rhodopsin-like; GPCR, rhodopsin-like, 7TM. Its molecular function is described by: histamine receptor activity; G-protein coupled serotonin receptor activity; G-protein coupled amine receptor activity. It is involved in the biological process described with: G-protein coupled receptor signaling pathway; serotonin receptor signaling pathway. 11 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; locomotor behavior defective; some die during embryonic stage; partially lethal; behavior defective."
FBgn0263111	cac	0.407792718	0.325074909	0.999936032	NA	CACNA1B;CACNA1A;CACNA1E;CACNA1C;CACNA1S;CACNA1D;CACNA1F	high;moderate;moderate;low;low;low;low	NA	transmembrane protein	NA	"The gene cacophony is referred to in FlyBase by the symbol Dmel\cac (CG43368, FBgn0263111). It is a protein_coding_gene from Drosophila melanogaster. It has 15 annotated transcripts and 15 polypeptides (14 unique). Gene sequence location is X:11931280..11985087. It has the cytological map location 10F8-11A1. Protein features are: EF-hand domain; Ion transport domain; Voltage-dependent L-type calcium channel, IQ-associated domain; Voltage-dependent calcium channel, L-type, alpha-1 subunit; Voltage-dependent calcium channel, alpha-1 subunit; Voltage-dependent calcium channel, alpha-1 subunit, IQ domain. Its molecular function is described by: high voltage-gated calcium channel activity; calcium ion binding; voltage-gated calcium channel activity; low voltage-gated calcium channel activity. It is involved in the biological process described with 23 unique terms, many of which group under: response to light stimulus; response to radiation; presynaptic process involved in chemical synaptic transmission; catabolic process; homeostatic process; sensory perception; regulation of membrane potential; regulation of heart rate; cell differentiation; epithelial fluid transport; regulation of homeostatic process; regulation of cellular component organization; chemical synaptic transmission. 74 alleles are reported. The phenotypes of these alleles manifest in: neuron part; bouton; photoreceptor cell; indirect flight muscle motor neuron MN5; cell part; capitate projection; presynaptic active zone; adult thorax; external compound sense organ; adult segment; synapse; neuromuscular junction. The phenotypic classes of alleles include: phenotype; mating defective; increased mortality; behavior defective."
FBgn0030943	CG6540	0.408029511	0.292619697	0.999936032	NUP35	NUP35	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6540 (FBgn0030943). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:18648182..18649489. It has the cytological map location 17C7. Protein features are: Nucleoporin, NUP53; RNA recognition motif domain; RNA-recognition motif (RRM) Nup35-type domain. Its molecular function is described by: phospholipid binding; single-stranded DNA binding; nucleocytoplasmic transporter activity. It is involved in the biological process described with: nuclear pore organization; NLS-bearing protein import into nucleus; regulation of transcription, DNA-templated. 9 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0038541	TyrRII	0.408062596	0.194528777	0.999936032	NA	DRD5;DRD1;ADRA1D;HTR4;HRH2;PTGER4;DRD2;DRD3;DRD4	low;low;low;low;low;low;low;low;low	NA	transmembrane protein	GPCR	"The gene Tyramine receptor II is referred to in FlyBase by the symbol Dmel\TyrRII (CG16766, FBgn0038541). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 3R:17736611..17747470. It has the cytological map location 90C2. Protein features are: G protein-coupled receptor, rhodopsin-like; GPCR, rhodopsin-like, 7TM. Its molecular function is described by: tyramine receptor activity; G-protein coupled amine receptor activity. It is involved in the biological process described with: cellular response to amine stimulus; G-protein coupled receptor signaling pathway; adenylate cyclase-activating dopamine receptor signaling pathway; learning; tyramine signaling pathway; phospholipase C-activating dopamine receptor signaling pathway; adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway. 11 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, in adult male stages.  "
FBgn0034488	CG11208	0.40815646	0.234986053	0.999936032	NA	HACL1;ILVBL	high;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11208 (FBgn0034488). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:20242752..20245388. It has the cytological map location 56F11. Protein features are: DHS-like NAD/FAD-binding domain; Thiamin diphosphate-binding fold; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain. Its molecular function is described by: catalytic activity; thiamine pyrophosphate binding; magnesium ion binding. It is involved in the biological process described with: fatty acid alpha-oxidation. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in adult female stages.  "
FBgn0267486	Ptp36E	0.408316104	0.327713595	0.999936032	NA	PTPRK;PTPRA;PTPRE;PTPRU;PTPRM;PTPRT	high;moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"The gene Protein tyrosine phosphatase 36E is referred to in FlyBase by the symbol Dmel\Ptp36E (CG7180, FBgn0267486). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:18180884..18185007. It has the cytological map location 36E6. Protein features are: PTP type protein phosphatase; Protein-tyrosine phosphatase, active site; Protein-tyrosine phosphatase, catalytic; Protein-tyrosine phosphatase-like; Tyrosine specific protein phosphatases domain. Its molecular function is unknown. It is involved in the biological process described with: protein dephosphorylation. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable."
FBgn0034707	MED16	0.408865267	0.322820547	0.999936032	MED16	MED16	high	Co-factor	NA	NA	"The gene Mediator complex subunit 16 is referred to in FlyBase by the symbol Dmel\MED16 (CG5465, FBgn0034707). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:22183138..22185892. It has the cytological map location 58C5-58C7. Protein features are: Mediator complex, subunit Med16; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: RNA polymerase II transcription cofactor activity; transcription coactivator activity. It is involved in the biological process described with: regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-templated; transcription initiation from RNA polymerase II promoter; response to heat; response to lipopolysaccharide. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0020407	asun	0.409855744	0.311172276	0.999936032	ASUN	ASUN	high	NA	NA	NA	"The gene asunder is referred to in FlyBase by the symbol Dmel\asun (CG6814, FBgn0020407). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:16264271..16266891. It has the cytological map location 89B9. Protein features are: Cell cycle regulator Mat89Bb. Its molecular function is described by: . It is involved in the biological process described with: regulation of mitotic cell cycle; spermatogenesis; regulation of fertilization; oocyte nucleus localization involved in oocyte dorsal/ventral axis specification; centrosome localization; flagellated sperm motility; snRNA 3'-end processing; posterior mRNA localization involved in anterior/posterior axis specification; dorsal appendage formation. 11 alleles are reported. The phenotypes of these alleles manifest in: ovary; female germline cyst; cell component; gamete; oocyte nucleus; male germline cell; acellular anatomical structure; primary spermatocyte cyst; external encapsulating structure; microtubule cytoskeleton. The phenotypic classes of alleles include: meiotic cell cycle defective; viable; male sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0051715	CG31715	0.409933307	0.243628058	0.999936032	NA	MTPN;LUZP6	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31715 (FBgn0051715). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:10341616..10342523. It has the cytological map location 31D9. Protein features are: Ankyrin repeat; Ankyrin repeat-containing domain. Its molecular function is described by: . It is involved in the biological process described with: . 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0051363	Jupiter	0.410000292	0.270550029	0.999936032	NA	HN1L;HN1	high;high	NA	NA	NA	"The gene Jupiter is referred to in FlyBase by the symbol Dmel\Jupiter (CG31363, FBgn0051363). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (all unique). Gene sequence location is 3R:11590386..11619906. It has the cytological map location 86E11-86E13. Protein features are: Microtubule-associated protein Jupiter. Its molecular function is described by: structural constituent of cytoskeleton; microtubule binding. It is involved in the biological process described with: positive regulation of microtubule polymerization. 30 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable; lethal - all die during P-stage; fertile; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0051697	CG31697	0.410288617	0.307899738	0.999936032	NA	SELENOI;CHPT1;CEPT1	low;low;low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG31697 (FBgn0051697). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:19535448..19536104. It has the cytological map location 37F1. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed in adult male stages.
FBgn0263608	l(3)72Dr	0.410288617	0.307899738	0.999936032	NA	GGH	moderate	NA	NA	NA	"The gene lethal (3) 72Dr is referred to in FlyBase by the symbol Dmel\l(3)72Dr (CG32154, FBgn0263608). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:16237723..16239462. It has the cytological map location 72D10. Protein features are: Class I glutamine amidotransferase-like; Peptidase C26; Peptidase C26, gamma-glutamyl hydrolase. Its molecular function is described by: gamma-glutamyl-peptidase activity. It is involved in the biological process described with: tetrahydrofolylpolyglutamate metabolic process. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal."
FBgn0250732	gfzf	0.410368582	0.326319582	0.999936032	NA	GSTO2;GSTT2B;GSTT1;MARS;VARS;GSTT2;EEF1G;EEF1E1	low;low;low;low;low;low;low;low	NA	NA	NA	"The gene GST-containing FLYWCH zinc-finger protein is referred to in FlyBase by the symbol Dmel\gfzf (CG33546, FBgn0250732). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:7145880..7150968. It has the cytological map location 84C1-84D1. Protein features are: Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Thioredoxin-like fold; Zinc finger, FLYWCH-type. Its molecular function is described by: nucleic acid binding; glutathione binding; glutathione transferase activity. It is involved in the biological process described with: mitotic G2 DNA damage checkpoint; positive regulation of Ras protein signal transduction; positive regulation of ERK1 and ERK2 cascade; glutathione metabolic process. 33 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; embryonic/larval neuroblast; ganglion mother cell; mesothoracic tergum. The phenotypic classes of alleles include: phenotype; increased mortality during development; increased mortality; some die during P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0265767	zyd	0.41037219	0.230833796	0.999936032	NA	SLC24A4;SLC24A3;SLC24A5;SLC24A2	high;high;moderate;low	NA	transmembrane protein	NA	"The gene zydeco is referred to in FlyBase by the symbol Dmel\zyd (CG2893, FBgn0265767). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (5 unique). Gene sequence location is X:23022898..23035550. Protein features are: Sodium/calcium exchanger membrane region; Sodium/potassium/calcium exchanger. Its molecular function is described by: sodium ion binding; calcium, potassium:sodium antiporter activity; calcium channel activity; potassium ion binding; calcium ion binding. It is involved in the biological process described with: cellular calcium ion homeostasis; calcium-mediated signaling; calcium ion transmembrane transport. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: bang sensitive; behavior defective; partially lethal - majority die; viable; neurophysiology defective."
FBgn0034759	CG13511	0.410620985	0.256935023	0.999936032	NA	CDIP1;LITAF	moderate;moderate	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG13511 (FBgn0034759). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:22657901..22661389. It has the cytological map location 58F4. Protein features are: LPS-induced tumour necrosis factor alpha factor. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during early pupal stages.
FBgn0015576	alpha-Est8	0.410670849	0.268844798	0.999936032	NA	CES1	moderate	NA	NA	NA	"The gene ‘±-Esterase-8 is referred to in FlyBase by the symbol Dmel\‘±-Est8 (CG1121, FBgn0015576). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:7509343..7515670. It has the cytological map location 84D9. Protein features are: Alpha/Beta hydrolase fold; Carboxylesterase type B, active site; Carboxylesterase type B, conserved site; Carboxylesterase, type B. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed in adult male stages.  "
FBgn0022224	ubl	0.411393212	0.28141513	0.999936032	NA	UBL5	high	NA	NA	NA	"The gene ubiquitin like is referred to in FlyBase by the symbol Dmel\ubl (CG3450, FBgn0022224). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:6810011..6810530. It has the cytological map location 42D4. Protein features are: Ubiquitin domain; Ubiquitin-related domain. Its molecular function is described by: protein tag. It is involved in the biological process described with: cellular protein modification process; mRNA splicing, via spliceosome; positive regulation of MyD88-dependent toll-like receptor signaling pathway. 4 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum; embryonic/larval neuroblast; ganglion mother cell. The phenotypic classes of alleles include: some die during P-stage; increased mortality; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages.  "
FBgn0032249	TBC1D16	0.411778984	0.323214005	0.999936032	NA	TBC1D16	high	NA	NA	NA	"The gene TBC1 domain family member 16 is referred to in FlyBase by the symbol Dmel\TBC1D16 (CG5337, FBgn0032249). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:10432687..10435656. It has the cytological map location 31E2. Protein features are: Rab-GTPase-TBC domain. Its molecular function is described by: Rab GTPase binding; GTPase activator activity. It is involved in the biological process described with: activation of GTPase activity; regulation of GTPase activity; regulation of vesicle fusion; intracellular protein transport. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0035934	TrpA1	0.412921208	0.317649564	0.999936032	TRPA1	TRPA1	high	NA	transmembrane protein	NA	"The gene Transient receptor potential cation channel A1 is referred to in FlyBase by the symbol Dmel\TrpA1 (CG5751, FBgn0035934). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (all unique). Gene sequence location is 3L:8894404..8904790. It has the cytological map location 66E3. Protein features are: Ankyrin repeat; Ankyrin repeat-containing domain; Ion transport domain. Its molecular function is described by: calcium channel activity; temperature-gated cation channel activity; ligand-gated ion channel activity; cation channel activity. It is involved in the biological process described with 18 unique terms, many of which group under: establishment of localization; regulation of signal transduction; transmembrane transport; thermotaxis; rhythmic process; localization; energy taxis; divalent metal ion transport; response to mechanical stimulus; phototransduction; second-messenger-mediated signaling. 46 alleles are reported. The phenotypes of these alleles manifest in: neuromuscular junction; olfactory system; embryonic/larval thoracic/abdominal ventral sensory cluster; dendrite; adult nervous system; dendritic arborizing neuron; indirect flight muscle motor neuron; olfactory receptor neuron; somatodendritic compartment; synapse. The phenotypic classes of alleles include: behavior defective; mating defective; phenotype; temperature response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0026361	5-Sep	0.412964833	0.242590735	0.999936032	NA	SEPT11;SEPT6;SEPT8;SEPT10;SEPT14	moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"The gene Septin 5 is referred to in FlyBase by the symbol Dmel\Sep5 (CG2916, FBgn0026361). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:7960133..7961921. It has the cytological map location 43F8. Protein features are: P-loop containing nucleoside triphosphate hydrolase; Septin; Septin-type guanine nucleotide-binding (G) domain. Its molecular function is described by: GTP binding; GTPase activity. It is involved in the biological process described with: mitotic cytokinesis; regulation of cell cycle; imaginal disc development. 13 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0086370	sra	0.413490497	0.260269316	0.999936032	NA	RCAN2;RCAN3;RCAN1	high;moderate;moderate	NA	NA	NA	"The gene sarah is referred to in FlyBase by the symbol Dmel\sra (CG6072, FBgn0086370). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:16186999..16197584. It has the cytological map location 89B12-89B7. Protein features are: Calcipressin; RNA recognition motif domain. Its molecular function is described by: protein binding; nucleic acid binding; calcium-dependent protein serine/threonine phosphatase regulator activity. It is involved in the biological process described with 11 unique terms, many of which group under: multicellular organismal process; learning; single-multicellular organism process; regulation of cellular process; mitochondrion organization; nuclear division; mating behavior; regulation of biological quality; regulation of calcium-mediated signaling; memory; cell activation. 89 alleles are reported. The phenotypes of these alleles manifest in: membrane-bounded organelle; meiosis I cell cycle phase; eye disc; embryonic/larval cuticle; embryonic/larval brain; transport vesicle; embryonic/larval integumentary system; prepupa; anaphase; axon; pronucleus; sensory organ cell. The phenotypic classes of alleles include: mating behavior defective; sterile; partially lethal; behavior defective; fertile; increased mortality; short lived; meiotic cell cycle defective; visible; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, during early pupal stages.  "
FBgn0004657	mys	0.41373996	0.237110347	0.999936032	NA	ITGB1;ITGB2;ITGB7;ITGB3;ITGB4;ITGB5;ITGB6;ITGB8;ITGBL1	high;moderate;moderate;moderate;moderate;moderate;moderate;low;moderate	NA	transmembrane protein	NA	"The gene myospheroid is referred to in FlyBase by the symbol Dmel\mys (CG1560, FBgn0004657). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is X:8061645..8070237. It has the cytological map location 7D5. Protein features are: EGF-like domain, extracellular; Integrin beta subunit; Integrin beta subunit, VWA domain; Integrin beta subunit, cytoplasmic domain; Integrin beta subunit, tail; Integrin domain; von Willebrand factor, type A. Its molecular function is described by: extracellular matrix protein binding; cell adhesion molecule binding; protein heterodimerization activity; receptor activity; protein binding. It is involved in the biological process described with 37 unique terms, many of which group under: biological adhesion; actin filament organization; central nervous system development; developmental growth involved in morphogenesis; calcium-dependent cell-matrix adhesion; immune system development; system process; actin filament bundle organization; negative regulation of cell migration; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules. 158 alleles are reported. The phenotypes of these alleles manifest in: presumptive embryonic salivary gland; somatic precursor cell; pupal/adult digestive system; synapse; adult abdominal segment; cell component; hub cell; lobe system of adult mushroom body; abdominal 2 lateral longitudinal muscle 1; external encapsulating structure; stage 8 embryo; actomyosin; muscle tendon junction; cell projection; cardioblast. The phenotypic classes of alleles include: wound healing defective; chemical sensitive; wild-type; flightless; lethal; phenotype; increased mortality during development; smell perception defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period.  "
FBgn0035941	CG13313	0.414193327	0.248395067	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG13313 (FBgn0035941). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:8958857..8960921. It has the cytological map location 66E5. Protein features are: CUB domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed in adult male stages.
FBgn0052686	CG32686	0.414527774	0.304648179	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG32686 (FBgn0052686). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:10371717..10375316. It has the cytological map location 9B12. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed in adult male stages.
FBgn0013673	mt:ATPase8	0.414649209	0.307436426	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene mitochondrial ATPase subunit 8 is referred to in FlyBase by the symbol Dmel\mt:ATPase8 (CG34072, FBgn0013673). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is mitochondrion_genome:3907..4068. Protein features are: ATP synthase protein 8, metazoa. Its molecular function is described by: hydrogen ion transmembrane transporter activity. It is involved in the biological process described with: ATP synthesis coupled proton transport. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very low expression to a trough of no expression detected.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, during early larval stages, during early pupal stages, in adult male stages.  "
FBgn0051460	CG31460	0.414687314	0.309044568	0.999936032	NA	KRTCAP2	high	Maybe TF	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31460 (FBgn0051460). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:8562673..8563445. It has the cytological map location 85A3. Protein features are: Keratinocyte-associated protein 2. Its molecular function is described by: . It is involved in the biological process described with: . 9 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: lethal; fertile; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0034331	CG15067	0.414687829	0.307348375	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG15067 (FBgn0034331). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:18384824..18385589. It has the cytological map location 55C4. Protein features are: Immune-induced protein Dim. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum; embryonic/larval neuroblast; ganglion mother cell. The phenotypic classes of alleles include: visible; viable; lethal; neuroanatomy defective; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed in adults stages of both sexes.
FBgn0035205	Ctr9	0.414841983	0.279573742	0.999936032	NA	CTR9	high	NA	NA	NA	"The gene Ctr9 is referred to in FlyBase by the symbol Dmel\Ctr9 (CG2469, FBgn0035205). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:1307224..1311805. It has the cytological map location 61F5-61F6. Protein features are: Methylthioribose-1-phosphate isomerase-like, N-terminal domain; RNA polymerase-associated protein Ctr9; Tetratricopeptide repeat; Tetratricopeptide repeat 2; Tetratricopeptide repeat-containing domain; Tetratricopeptide-like helical domain. Its molecular function is described by: RNA polymerase II core binding; SH2 domain binding. It is involved in the biological process described with: regulation of transcription, DNA-templated; regulation of gene expression; negative regulation of neuroblast proliferation; positive regulation of transcription from RNA polymerase II promoter; regulation of histone H3-K4 methylation; ventral cord development; germ cell development. 10 alleles are reported. The phenotypes of these alleles manifest in: neuroblast NB5-6 of thorax; embryonic/larval neuroblast; germ cell nucleus; germarium; female germline cell; egg chamber; neuroblast NB3-3; apterous-expressing neuron of the lateral cluster of the thorax Ap4; apterous-expressing neuron of the lateral cluster of the thorax; ventral nerve cord primordium. The phenotypic classes of alleles include: decreased cell number; neuroanatomy defective; cell number defective; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0036397	Nprl3	0.415090478	0.319740723	0.999936032	NA	NPRL3	high	NA	NA	NA	"The gene Nitrogen permease regulator-like 3 is referred to in FlyBase by the symbol Dmel\Nprl3 (CG8783, FBgn0036397). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3L:13999380..14001880. It has the cytological map location 70C11. Protein features are: Nitrogen permease regulator 3. Its molecular function is described by: protein binding. It is involved in the biological process described with 11 unique terms, many of which group under: cellular response to nutrient levels; regulation of TORC1 signaling; cellular response to amino acid starvation; regulation of cell size; glycerolipid metabolic process; response to stress; single-organism developmental process; multicellular organism reproduction; single-organism catabolic process; germarium-derived egg chamber formation; response to external stimulus; single-organism cellular process. 9 alleles are reported. The phenotypes of these alleles manifest in: follicle cell; egg chamber; fat body. The phenotypic classes of alleles include: sterile; increased cell death; increased mortality during development; phenotype; increased mortality; short lived; majority die during P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0261277	rtv	0.415220791	0.318731878	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene retroactive is referred to in FlyBase by the symbol Dmel\rtv (CG1397, FBgn0261277). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is X:11152484..11153990. It has the cytological map location 10A8. Protein features are: Protein quiver. Its molecular function is described by: GPI anchor binding. It is involved in the biological process described with: chitin-based embryonic cuticle biosynthetic process; regulation of tube architecture, open tracheal system; regulation of synaptic transmission, cholinergic; open tracheal system development; sleep; regulation of tube diameter, open tracheal system; positive regulation of voltage-gated potassium channel activity; chitin biosynthetic process. 17 alleles are reported. The phenotypes of these alleles manifest in: multicellular structure; anatomical group; organ system; cuticle; dorsal closure embryo; epithelium; tagma; cephalopharyngeal skeleton; anatomical structure; non-connected developing system; embryonic/larval dorsal trunk. The phenotypic classes of alleles include: lethal - all die before end of P-stage; phenotype; increased mortality during development; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during early pupal stages.  "
FBgn0034786	CG13531	0.415249812	0.322721602	0.999936032	NA	SPG11	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13531 (FBgn0034786). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:22847832..22853827. It has the cytological map location 59B2-59B3. Protein features are: Spatacsin; Spatacsin, C-terminal domain; Tetratricopeptide-like helical domain. Its molecular function is described by: . It is involved in the biological process described with: axon extension. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0034296	CG10912	0.415472704	0.224922807	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10912 (FBgn0034296). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:18056064..18057065. It has the cytological map location 55B2. Protein features are: Protein of unknown function DUF725. Its molecular function is unknown. It is involved in the biological process described with: cold acclimation. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period, during early pupal stages, in adult male stages.  "
FBgn0003429	slo	0.415613356	0.295386014	0.999936032	NA	KCNMA1;KCNU1	high;moderate	NA	transmembrane protein	NA	"The gene slowpoke is referred to in FlyBase by the symbol Dmel\slo (CG10693, FBgn0003429). It is a protein_coding_gene from Drosophila melanogaster. It has 23 annotated transcripts and 23 polypeptides (all unique). Gene sequence location is 3R:24662491..24711595. It has the cytological map location 96A14-96A17. Protein features are: Calcium-activated potassium channel Slo-1; Ion transport domain; NAD(P)-binding domain; Potassium channel, BK, alpha subunit; Voltage-gated potassium channel. Its molecular function is described by: protein binding; calcium-activated potassium channel activity; large conductance calcium-activated potassium channel activity; voltage-gated potassium channel activity. It is involved in the biological process described with: potassium ion transport; circadian rhythm; circadian behavior; response to drug; regulation of synaptic growth at neuromuscular junction; male courtship behavior, veined wing generated song production; transmembrane transport; negative regulation of neuromuscular synaptic transmission. 54 alleles are reported. The phenotypes of these alleles manifest in: neuron; visceral muscle fiber; embryonic/larval midgut; adult olfactory receptor neuron ab11a; neuromuscular junction; antennal basiconic sensillum ab12; indirect flight muscle; NMJ bouton. The phenotypic classes of alleles include: circadian rhythm defective; phenotype; increased mortality during development; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.  "
FBgn0000008	a	0.416764499	0.269242504	0.999936032	NA	PDZD2;IL16	high;moderate	NA	NA	NA	"The gene arc is referred to in FlyBase by the symbol Dmel\a (CG6741, FBgn0000008). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 2R:22136968..22172834. It has the cytological map location 58C1-58C5. Protein features are: FERM and PDZ domain-containing protein 2; PDZ domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: . It is involved in the biological process described with: bicellular tight junction assembly; compound eye development. 39 alleles are reported. The phenotypes of these alleles manifest in: posterior scutellar bristle; wing; ommatidium; crossvein; macrochaeta; eye. The phenotypic classes of alleles include: phenotype; increased mortality during development; increased mortality; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the pupal period.  "
FBgn0038199	CCHa1	0.41679371	0.292905358	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene CCHamide-1 is referred to in FlyBase by the symbol Dmel\CCHa1 (CG14358, FBgn0038199). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:14092504..14096835. It has the cytological map location 88A8. Its molecular function is described by: neuropeptide hormone activity. It is involved in the biological process described with: neuropeptide signaling pathway. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0035356	CG16986	0.416909014	0.224614044	0.999936032	ACOT13	ACOT13	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG16986 (FBgn0035356). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:2600331..2601536. It has the cytological map location 62E7. Protein features are: HotDog domain; Phenylacetic acid degradation-related domain; Thioesterase domain. Its molecular function is described by: acyl-CoA hydrolase activity. It is involved in the biological process described with: protein homotetramerization. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed in adult male stages.
FBgn0026326	Mad1	0.416973491	0.313791683	0.999936032	MAD1L1	MAD1L1	high	NA	NA	NA	"The gene Mitotic arrest-deficient 1 is referred to in FlyBase by the symbol Dmel\Mad1 (CG2072, FBgn0026326). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:9288957..9291565. It has the cytological map location 45C4. Protein features are: Spindle assembly checkpoint component Mad1. Its molecular function is described by: . It is involved in the biological process described with: attachment of mitotic spindle microtubules to kinetochore; mitotic spindle assembly checkpoint. 10 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; embryonic/larval brain; mesothoracic tergum. The phenotypic classes of alleles include: size defective; neuroanatomy defective; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0030530	jub	0.417141755	0.296573528	0.999936032	NA	LIMD1;WTIP;AJUBA	high;high;moderate	Maybe TF	NA	NA	"The gene Ajuba LIM protein is referred to in FlyBase by the symbol Dmel\jub (CG11063, FBgn0030530). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is X:13826041..13830317. It has the cytological map location 12C6. Protein features are: WD40/YVTN repeat-like-containing domain; Zinc finger, LIM-type. Its molecular function is described by: transcription corepressor activity; protein binding; actin binding. It is involved in the biological process described with 11 unique terms, many of which group under: organonitrogen compound metabolic process; response to decreased oxygen levels; organelle organization; protein localization to microtubule cytoskeleton; mitotic cell cycle; regulation of signaling; response to stress; cell cycle; reproduction; cellular protein localization. 12 alleles are reported. The phenotypes of these alleles manifest in: centrosome; eye; wing; wing blade; spindle; neuroblast. The phenotypic classes of alleles include: phenotype; increased mortality during development; increased mortality; cell number defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0030240	CG2202	0.417216428	0.315946854	0.999936032	NA	XAF1;ZNF260;ZNF146;ZNF471;ZNF383;ZNF546;ZSCAN20;ZNF665;ZNF69;ZNF449;INSM1;ZNF85;MAZ;ZNF3;ZBTB17;ZNF816;ZNF559;ZNF439;ZNF699;ZNF668;ZNF813;ZNF345;ZNF470;INSM2;ZNF558;ZNF555;VEZF1;ZNF846;ZNF721;ZNF263;ZNF689;ZNF836;ZNF778;ZNF502	low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG2202 (FBgn0030240). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:10848757..10852327. It has the cytological map location 9F5. Protein features are: KRAB domain C2H2 zinc finger family; Zinc finger C2H2-type; Zinc finger, AD-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: nucleic acid binding; zinc ion binding. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0039938	Sox102F	0.417329186	0.27592566	0.999936032	NA	SOX5;SOX6;SOX13	high;moderate;moderate	DNA-binding with transcription factor activity(HMG_box)	NA	NA	"The gene Sox102F is referred to in FlyBase by the symbol Dmel\Sox102F (CG11153, FBgn0039938). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 4:800436..834393. It has the cytological map location 102E1-102E3. Protein features are: High mobility group box domain. Its molecular function is unknown. It is involved in the biological process described with: positive regulation of heart contraction. 10 alleles are reported. The phenotypes of these alleles manifest in: somatic cell; adult integumentary system; neuron part; intracellular non-membrane-bounded organelle; central nervous system; multidendritic neuron; circulatory system; sensillum; microchaeta; intracellular part; eye; wing blade; nervous system. The phenotypic classes of alleles include: locomotor behavior defective; behavior defective; lethal; phenotype; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed at stages throughout the pupal period, in adult male stages.  "
FBgn0035152	CG3386	0.417483311	0.317846877	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG3386 (FBgn0035152). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 3L:680436..682470. It has the cytological map location 61C8. Protein features are: MADF domain. Its molecular function is described by: . It is involved in the biological process described with: . 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0039189	CG18528	0.417774413	0.319269929	0.999936032	GTPBP3	GTPBP3	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG18528 (FBgn0039189). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:24358095..24360144. It has the cytological map location 95F15. Protein features are: GTP binding domain; GTP-binding protein TrmE, N-terminal; MnmE, helical domain; P-loop containing nucleoside triphosphate hydrolase; Small GTP-binding protein domain; TrmE-type guanine nucleotide-binding domain; tRNA modification GTPase MnmE. Its molecular function is described by: GTP binding; GTPase activity. It is involved in the biological process described with: tRNA modification. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0004510	Ets97D	0.417979211	0.304442875	0.999936032	NA	GABPA;ETV5;ETV2;ETV1;ETV4	high;low;low;low;low	DNA-binding with transcription factor activity(Ets)	NA	NA	"The gene Ets at 97D is referred to in FlyBase by the symbol Dmel\Ets97D (CG6338, FBgn0004510). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:26910775..26912886. It has the cytological map location 97D7. Protein features are: Ets domain; GA-binding protein alpha subunit, N-terminal; Pointed domain; Sterile alpha motif/pointed domain; Transcription factor, GA-binding, alpha subunit; Winged helix-turn-helix DNA-binding domain. Its molecular function is described by: sequence-specific DNA binding; RNA polymerase II transcription factor activity, sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated; glutamine metabolic process; regulation of transcription from RNA polymerase II promoter; mitochondrion organization; regulation of glucose metabolic process; regulation of mitochondrion organization; pole plasm oskar mRNA localization; cellular response to starvation. 17 alleles are reported. The phenotypes of these alleles manifest in: cell part; fat body; organelle part; abdominal segment 6; eo support cell; border follicle cell; epithelial cell; external encapsulating structure; nucleoid; eo-type sensillum; acellular anatomical structure. The phenotypic classes of alleles include: visible; increased mortality during development; phenotype; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0004552	Akh	0.418639453	0.249620447	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene Adipokinetic hormone is referred to in FlyBase by the symbol Dmel\Akh (CG1171, FBgn0004552). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:4141467..4142070. It has the cytological map location 64A7. Protein features are: Adipokinetic hormone, conserved site; Adipokinetic hormone/red pigment-concentrating hormone. Its molecular function is described by: adipokinetic hormone receptor binding; neuropeptide hormone activity. It is involved in the biological process described with: lipid homeostasis; response to starvation; regulation of glucose metabolic process; carbohydrate homeostasis; neuropeptide signaling pathway. 13 alleles are reported. The phenotypes of these alleles manifest in: adult fat body; lipid particle; wing. The phenotypic classes of alleles include: size defective; viable; phenotype; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed in adult male stages.  "
FBgn0002121	l(2)gl	0.418754869	0.232875514	0.999936032	LLGL1	LLGL1;LLGL2	high;moderate	NA	NA	NA	"The gene lethal (2) giant larvae is referred to in FlyBase by the symbol Dmel\l(2)gl (CG2671, FBgn0002121). It is a protein_coding_gene from Drosophila melanogaster. It has 11 annotated transcripts and 11 polypeptides (4 unique). Gene sequence location is 2L:9839..21376. It has the cytological map location 21A5. Protein features are: Lethal giant larvae (Lgl)-like, C-terminal domain; Lethal giant larvae homologue 2; Lethal(2) giant larvae protein; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: myosin binding; SNARE binding; syntaxin binding; GTPase activator activity; protein kinase inhibitor activity; Rab GTPase binding; myosin II binding. It is involved in the biological process described with 48 unique terms, many of which group under: cell cycle; nitrogen compound transport; molting cycle, chitin-based cuticle; growth; regulation of Notch signaling pathway; cell-cell junction assembly; establishment or maintenance of bipolar cell polarity; spindle localization; asymmetric protein localization; cellular component morphogenesis; establishment or maintenance of polarity of larval imaginal disc epithelium; establishment or maintenance of apical/basal cell polarity; cell fate determination; positive regulation of cellular process; negative regulation of kinase activity; apical junction assembly; regulation of protein transport; molting cycle; establishment of spindle localization. 114 alleles are reported. The phenotypes of these alleles manifest in: intracellular organelle part; egg; embryonic/larval neuroblast; trachea; embryonic/larval circulatory system; cell component; salivary gland; anchoring junction; cephalopharyngeal skeleton; proteinaceous extracellular matrix; embryonic ventral epidermis. The phenotypic classes of alleles include: increased mortality during development; phenotype; visible; sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis.  "
FBgn0264562	Hr4	0.418764936	0.242914479	0.999936032	NA	NR6A1	high	DNA-binding with transcription factor activity(zf-C4)	NA	NA	"The gene Hormone receptor 4 is referred to in FlyBase by the symbol Dmel\Hr4 (CG43934, FBgn0264562). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (8 unique). Gene sequence location is X:1941940..2007956. It has the cytological map location 2B16-2C1. Protein features are: Armadillo-like helical; Nuclear hormone receptor; Nuclear hormone receptor, ligand-binding domain; WD40/YVTN repeat-like-containing domain; Zinc finger, NHR/GATA-type; Zinc finger, nuclear hormone receptor-type. Its molecular function is described by: RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding; steroid hormone receptor activity; zinc ion binding. It is involved in the biological process described with: regulation of transcription, DNA-templated; intracellular steroid hormone receptor signaling pathway; growth; cellular response to hypoxia; regulation of developmental growth. 70 alleles are reported. The phenotypes of these alleles manifest in: eye; spiracle; integumentary specialisation; cell; adipose system; anatomical cluster; tracheal metamere; pupal spiracle; compound sense organ; embryo; peripheral nervous system. The phenotypic classes of alleles include: some die during P-stage; phenotype; increased mortality during development; visible."
FBgn0002570	Mal-A1	0.419105841	0.220598291	0.999936032	NA	SLC3A1;SLC3A2	moderate;low	NA	NA	NA	"The gene Maltase A1 is referred to in FlyBase by the symbol Dmel\Mal-A1 (CG8696, FBgn0002570). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:8449664..8451904. It has the cytological map location 44D1. Protein features are: Glycoside hydrolase superfamily; Glycosyl hydrolase, family 13, catalytic domain. Its molecular function is described by: catalytic activity. It is involved in the biological process described with: carbohydrate metabolic process. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, in stages of adults of both sexes.  "
FBgn0038446	CG14903	0.419381819	0.250228281	0.999936032	PTRHD1	PTRHD1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14903 (FBgn0038446). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:16573179..16573752. It has the cytological map location 89B20. Protein features are: Peptidyl-tRNA hydrolase II domain; Peptidyl-tRNA hydrolase, PTH2. Its molecular function is described by: aminoacyl-tRNA hydrolase activity. It is involved in the biological process described with: . 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: female semi-sterile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0035392	CG1271	0.419413704	0.250324389	0.999936032	GK5	GK5;GK;GK2	high;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1271 (FBgn0035392). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 3L:3052514..3054906. It has the cytological map location 63A5. Protein features are: Carbohydrate kinase, FGGY; Carbohydrate kinase, FGGY, C-terminal; Carbohydrate kinase, FGGY, N-terminal; Carbohydrate kinase, FGGY, conserved site. Its molecular function is unknown. It is involved in the biological process described with: triglyceride metabolic process; glycerol-3-phosphate biosynthetic process; glycerol metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed during early pupal stages.  "
FBgn0039326	CG10562	0.420256172	0.222592215	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG10562 (FBgn0039326). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:25321053..25322757. It has the cytological map location 96D1. Protein features are: CHK kinase-like; Protein kinase-like domain; Protein of unknown function DUF227. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; myofibril. The phenotypic classes of alleles include: viable; visible; flightless. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages.
FBgn0040228	DCTN5-p25	0.420954813	0.259260708	0.999936032	NA	DCTN5	high	NA	NA	NA	"The gene Dynactin 5, p25 subunit is referred to in FlyBase by the symbol Dmel\DCTN5-p25 (CG10846, FBgn0040228). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:15005733..15006607. It has the cytological map location 35B8. Protein features are: Hexapeptide repeat; Trimeric LpxA-like. Its molecular function is unknown. It is involved in the biological process described with: microtubule-based movement; retrograde axonal transport; spermatogenesis. 17 alleles are reported. The phenotypes of these alleles manifest in: macrochaeta; mesothoracic tergum; wing. The phenotypic classes of alleles include: partially lethal - majority die; male sterile; viable; visible; lethal; female sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0250754	CG42232	0.420983967	0.299411238	0.999936032	NA	MAP1A;RTN4;RTN3	low;low;low	Maybe TF	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG42232 (FBgn0250754). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:16458280..16469663. It has the cytological map location 89B17. Protein features are: SMAD/FHA domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 10 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, during early pupal stages.  "
FBgn0010531	Ccs	0.421003146	0.252994402	0.999936032	NA	CCS	high	NA	NA	NA	"The gene Copper chaperone for superoxide dismutase is referred to in FlyBase by the symbol Dmel\Ccs (CG17753, FBgn0010531). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:10121486..10122574. It has the cytological map location 46F1. Protein features are: Heavy metal-associated domain, HMA; Superoxide dismutase, copper/zinc binding domain; Superoxide dismutase, copper/zinc, binding site. Its molecular function is described by: superoxide dismutase activity; zinc ion binding; superoxide dismutase copper chaperone activity. It is involved in the biological process described with: metal ion transport; superoxide metabolic process; protein stabilization; determination of adult lifespan; oxidation-reduction process; response to oxidative stress. 16 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; short lived; lethal; chemical sensitive. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0000416	Sap-r	0.421151849	0.220781001	0.999936032	NA	PSAP;PSAPL1;SFTPB	high;moderate;moderate	NA	transmembrane protein	NA	"The gene Saposin-related is referred to in FlyBase by the symbol Dmel\Sap-r (CG12070, FBgn0000416). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:30883464..30889062. It has the cytological map location 100A6-100A7. Protein features are: Saposin; Saposin A-type domain; Saposin B type domain; Saposin B type, region 2; Saposin-like; Saposin-like type B, region 1. Its molecular function is described by: G-protein coupled receptor binding; enzyme activator activity. It is involved in the biological process described with: sphingolipid metabolic process; dsRNA transport. 18 alleles are reported. The phenotypes of these alleles manifest in: cytoplasm; cell; membrane-bounded organelle; intracellular membrane-bounded organelle; neuropil; intracellular part; circulatory system; antennal lobe; mitochondrion; neuron part; tracheal system; adult brain. The phenotypic classes of alleles include: cell size defective; increased cell death; behavior defective; increased mortality; phenotype; neurophysiology defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0034186	CG8950	0.421673948	0.286778823	0.999936032	GTF3C3	GTF3C3	high	Maybe TF	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8950 (FBgn0034186). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:17059331..17062634. It has the cytological map location 53F3-53F4. Protein features are: Tetratricopeptide repeat; Tetratricopeptide repeat-containing domain; Tetratricopeptide-like helical domain. Its molecular function is described by: transcription factor activity, core RNA polymerase III binding. It is involved in the biological process described with: transcription from RNA polymerase III promoter. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0036835	CG14075	0.422123022	0.269143026	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14075 (FBgn0036835). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:18984961..18985634. It has the cytological map location 75F2. Its molecular function is unknown. It is involved in the biological process described with: sensory perception of pain. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: pain response defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during early larval stages, in adult male stages.  "
FBgn0261928	CG42795	0.422709052	0.232845332	0.999936032	NA	TBC1D30;TBC1D2B;TBC1D2	high;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG42795 (FBgn0261928). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (all unique). Gene sequence location is 3R:10225690..10251277. It has the cytological map location 86A1. Protein features are: Rab-GTPase-TBC domain; TBC1 domain family member 30, C-terminal. Its molecular function is described by: Rab GTPase binding; GTPase activator activity. It is involved in the biological process described with: regulation of vesicle fusion; regulation of GTPase activity; activation of GTPase activity; intracellular protein transport. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: pain response defective; short lived; viable."
FBgn0262647	Nup160	0.422734315	0.31331331	0.999936032	NA	NUP160	high	NA	NA	NA	"The gene Nucleoporin 160kD is referred to in FlyBase by the symbol Dmel\Nup160 (CG4738, FBgn0262647). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:11123777..11129335. It has the cytological map location 32D4. Its molecular function is described by: nucleocytoplasmic transporter activity; protein binding. It is involved in the biological process described with: mRNA export from nucleus; SMAD protein import into nucleus; double-strand break repair via homologous recombination. 34 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal - majority die; lethal; viable; lethal - all die during P-stage."
FBgn0044324	Chro	0.423208684	0.281165806	0.999936032	NA	CBX3	low	Chromatin regulation	NA	NA	"The gene Chromator is referred to in FlyBase by the symbol Dmel\Chro (CG10712, FBgn0044324). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is 3L:22873702..22878984. It has the cytological map location 80B1-80B2. Protein features are: Alpha/Beta hydrolase fold; Chromo domain; Chromo domain-like; Chromo/chromo shadow domain. Its molecular function is described by: protein binding; histone binding. It is involved in the biological process described with: metamorphosis; chromosome organization; chromosome segregation; metaphase plate congression; mitotic spindle assembly checkpoint; mitotic spindle organization. 32 alleles are reported. The phenotypes of these alleles manifest in: abdominal temporary eclosion muscle DA; mitotic spindle; embryonic/larval neuroblast; A1-7 dorsal oblique muscle; spindle; neuroblast; mushroom body neuroblast; wing; embryonic/larval brain; imaginal disc. The phenotypic classes of alleles include: increased mortality; some die during P-stage; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0032074	Tsp29Fa	0.423316996	0.21745817	0.999936032	CD63	CD63	high	NA	transmembrane protein	NA	"The gene Tetraspanin 29Fa is referred to in FlyBase by the symbol Dmel\Tsp29Fa (CG9494, FBgn0032074). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:8933962..8936096. It has the cytological map location 29F4. Protein features are: Tetraspanin; Tetraspanin, EC2 domain; Tetraspanin, conserved site; Tetraspanin/Peripherin. Its molecular function is described by: . It is involved in the biological process described with: cell surface receptor signaling pathway. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late larval stages.  "
FBgn0039687	Naa40	0.423781249	0.31332589	0.999936032	NA	NAA40	high	NA	NA	NA	"The gene N(alpha)-acetyltransferase 40 is referred to in FlyBase by the symbol Dmel\Naa40 (CG7593, FBgn0039687). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:29724159..29724950. It has the cytological map location 99B9. Protein features are: Acyl-CoA N-acyltransferase; GNAT domain. Its molecular function is described by: peptide alpha-N-acetyltransferase activity. It is involved in the biological process described with: phagocytosis; N-terminal protein amino acid acetylation. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0036482	CG13457	0.42410289	0.157270291	0.999936032	NA	RNPS1	low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13457 (FBgn0036482). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:15127940..15131378. It has the cytological map location 71B5. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed at stages throughout the pupal period, in adult male stages.  "
FBgn0085385	bma	0.424272485	0.242962686	0.999936032	NA	SCYL2	moderate	NA	NA	NA	"The gene black match is referred to in FlyBase by the symbol Dmel\bma (CG34356, FBgn0085385). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:9908120..9967298. It has the cytological map location 67D1-67D2. Protein features are: Armadillo-type fold; Protein kinase domain; Protein kinase-like domain. Its molecular function is described by: ATP binding; protein kinase activity. It is involved in the biological process described with: detection of temperature stimulus involved in sensory perception of pain; protein phosphorylation. 9 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: visible; viable; body color defective; some die during pupal stage; heat stress response defective; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed during late pupal stages.  "
FBgn0031885	Mnn1	0.424753892	0.285969032	0.999936032	NA	MEN1	high	NA	NA	NA	"The gene Menin 1 is referred to in FlyBase by the symbol Dmel\Mnn1 (CG13778, FBgn0031885). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:7056301..7063586. It has the cytological map location 27D7. Protein features are: Menin; Tetratricopeptide-like helical domain. Its molecular function is described by: Y-form DNA binding; chromatin binding; double-stranded DNA binding; histone-lysine N-methyltransferase activity; transcription regulatory region DNA binding. It is involved in the biological process described with 18 unique terms, many of which group under: cellular aromatic compound metabolic process; response to abiotic stimulus; proboscis development; mitotic G1/S transition checkpoint; response to ionizing radiation; response to decreased oxygen levels; response to heat; RNA metabolic process; mitotic cell cycle phase transition; aging; response to oxidative stress. 23 alleles are reported. The phenotypes of these alleles manifest in: chaeta; wing; distiproboscis; adult thorax. The phenotypic classes of alleles include: phenotype; increased mortality during development; viable; stress response defective; fertile; lethal; radiation sensitive; chemical sensitive; DNA repair defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0086691	UK114	0.425289075	0.218057338	0.999936032	NA	RIDA	high	NA	NA	NA	"The gene UK114 is referred to in FlyBase by the symbol Dmel\UK114 (CG15261, FBgn0086691). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:15274181..15275091. It has the cytological map location 35D1. Protein features are: Endoribonuclease L-PSP/chorismate mutase-like; RidA family; RidA, conserved site; YjgF/YER057c/UK114 family. Its molecular function is unknown. It is involved in the biological process described with: protein folding. 6 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed at stages throughout the larval period.  "
FBgn0053198	pen-2	0.425332188	0.265500663	0.999936032	NA	PSENEN;LIN37	high;low	NA	transmembrane protein	NA	"The gene presenilin enhancer is referred to in FlyBase by the symbol Dmel\pen-2 (CG33198, FBgn0053198). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:18277439..18278762. It has the cytological map location 55C2. Protein features are: Gamma-secretase aspartyl protease complex, presenilin enhancer-2 subunit. Its molecular function is unknown. It is involved in the biological process described with: Notch receptor processing. 18 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0053012	CG33012	0.425459737	0.310568309	0.999936032	NA	ERMP1	moderate	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG33012 (FBgn0053012). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:12367353..12370886. It has the cytological map location 49A1. Protein features are: Peptidase M28. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during late larval stages.
FBgn0053116	CG33116	0.425474859	0.246164555	0.999936032	NA	SELENOI;CEPT1	high;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG33116 (FBgn0053116). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:19533479..19537363. It has the cytological map location 37F1. Protein features are: CDP-alcohol phosphatidyltransferase; Choline/ethanolamine phosphotransferase. Its molecular function is described by: phosphotransferase activity, for other substituted phosphate groups. It is involved in the biological process described with: phospholipid biosynthetic process. 13 alleles are reported. The phenotype of these alleles manifest in: chaeta. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0033921	tej	0.426352865	0.222678191	0.999936032	NA	TDRD5;TDRD7	high;low	NA	NA	NA	"The gene tejas is referred to in FlyBase by the symbol Dmel\tej (CG8589, FBgn0033921). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:14300103..14302353. It has the cytological map location 50F1. Protein features are: OST-HTH/LOTUS domain; Staphylococcal nuclease (SNase-like), OB-fold/extended TUDOR domain; Tudor domain. Its molecular function is unknown. It is involved in the biological process described with: negative regulation of transposition; karyosome formation; piRNA biosynthetic process. 13 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: female sterile germline-dependent; female semi-sterile; viable; female sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0265416	Neto	0.4264435	0.179136649	0.999936032	NA	NETO2;NETO1	high;moderate	NA	transmembrane protein	NA	"The gene Neuropilin and tolloid-like is referred to in FlyBase by the symbol Dmel\Neto (CG44328, FBgn0265416). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is X:13445903..13527282. It has the cytological map location 12A2. Protein features are: CUB domain; Low-density lipoprotein (LDL) receptor class A repeat; Tetratricopeptide-like helical domain. Its molecular function is described by: . It is involved in the biological process described with 13 unique terms, many of which group under: cellular protein localization; locomotion; cellular component organization; cellular localization; postsynaptic membrane organization; single-multicellular organism process; cellular response to endogenous stimulus; flight; regulation of cellular process; localization. 35 alleles are reported. The phenotypes of these alleles manifest in: chaeta; type I bouton; neuromuscular junction; embryonic/larval neuromuscular junction; mesothoracic tergum; terminal bouton. The phenotypic classes of alleles include: hatching behavior defective; neurophysiology defective; phenotype; fertile; increased mortality; paralytic; gravitaxis defective; some die during pupal stage; neuroanatomy defective."
FBgn0069969	CG40498	0.426600853	0.292551659	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG40498 (FBgn0069969). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is 2R:924636..951252. Its molecular function is described by: . It is involved in the biological process described with: . One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during late pupal stages.  "
FBgn0013347	TfIIA-S	0.42765762	0.232669828	0.999936032	NA	GTF2A2	high	DNA-binding with transcription factor activity	NA	NA	"The gene Transcription-factor-IIA-S is referred to in FlyBase by the symbol Dmel\TfIIA-S (CG5163, FBgn0013347). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:23890388..23891060. It has the cytological map location 95C8. Protein features are: Transcription factor IIA, beta-barrel; Transcription factor IIA, helical; Transcription initiation factor IIA, gamma subunit; Transcription initiation factor IIA, gamma subunit, C-terminal; Transcription initiation factor IIA, gamma subunit, N-terminal. Its molecular function is described by: RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly; TBP-class protein binding; RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly. It is involved in the biological process described with: positive regulation of sequence-specific DNA binding transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter. 16 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; photoreceptor cell R6; embryonic/larval neuroblast; photoreceptor cell; mesothoracic tergum; trichogen cell; eye; photoreceptor cell R7; photoreceptor cell R1. The phenotypic classes of alleles include: neuroanatomy defective; increased mortality; lethal - all die before end of second instar larval stage; visible; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-18 hour embryonic stages.  "
FBgn0037327	PEK	0.427825395	0.267765084	0.999936032	NA	EIF2AK3;EIF2AK2	high;moderate	NA	NA	NA	"The gene pancreatic eIF-2‘± kinase is referred to in FlyBase by the symbol Dmel\PEK (CG2087, FBgn0037327). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3R:5458563..5464753. It has the cytological map location 83A4. Protein features are: Protein kinase domain; Protein kinase, ATP binding site; Protein kinase-like domain; Pyrrolo-quinoline quinone beta-propeller repeat; Quinoprotein alcohol dehydrogenase-like superfamily; Serine/threonine-protein kinase, active site. Its molecular function is described by: protein kinase activity; ATP binding; elongation factor-2 kinase activity. It is involved in the biological process described with: regulation of G2/M transition of mitotic cell cycle; positive regulation of JNK cascade; positive regulation of autophagy; PERK-mediated unfolded protein response; protein phosphorylation. 11 alleles are reported. The phenotypes of these alleles manifest in: abdominal dorsal multidendritic neuron ddaC; eye disc posterior to the morphogenetic furrow; eye; adult gut; eye disc; dendrite. The phenotypic classes of alleles include: lethal - all die before end of P-stage; viable; increased mortality during development; phenotype; mitotic cell cycle defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0030243	CG2186	0.42800081	0.270666409	0.999936032	NA	RBM33	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG2186 (FBgn0030243). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:10857655..10866246. It has the cytological map location 9F5. Its molecular function is unknown. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0034098	krimp	0.428342814	0.233357389	0.999936032	NA	NA	NA	NA	NA	NA	"The gene krimper is referred to in FlyBase by the symbol Dmel\krimp (CG15707, FBgn0034098). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:16238103..16240722. It has the cytological map location 53A1. Protein features are: Staphylococcal nuclease (SNase-like), OB-fold/extended TUDOR domain; Tudor domain; Zinc finger, CCCH-type. Its molecular function is described by: metal ion binding. It is involved in the biological process described with: oocyte dorsal/ventral axis specification; karyosome formation; negative regulation of oskar mRNA translation. 14 alleles are reported. The phenotype of these alleles manifest in: chorion. The phenotypic classes of alleles include: female semi-sterile; female sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0052683	CG32683	0.428342814	0.233357389	0.999936032	NA	ARRB1;SAG;ARR3;ARRB2	moderate;moderate;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32683 (FBgn0052683). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:10410391..10454895. It has the cytological map location 9C1-9C4. Protein features are: Arrestin; Arrestin C-terminal-like domain; Arrestin, N-terminal; Arrestin-like, N-terminal; Immunoglobulin E-set. Its molecular function is unknown. It is involved in the biological process described with: signal transduction. 11 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.  "
FBgn0267117	CR45557	0.428342814	0.233357389	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CR45557 (FBgn0267117).The gene has a gene model, but the supporting evidence is inconclusive. It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3R:32015941..32026928. It has the cytological map location 100E2. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. The phenotypic class of allele includes: viable."
FBgn0030673	CG15601	0.42903175	0.304500243	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG15601 (FBgn0030673). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is X:15710647..15712309. It has the cytological map location 13E8. Protein features are: MADF domain. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 06-12 hour embryonic stages.
FBgn0038511	cysu	0.429502611	0.242789561	0.999936032	NA	TPO;LPO;PXDNL;EPX	moderate;low;low;low	NA	NA	NA	"The gene Curly Su is referred to in FlyBase by the symbol Dmel\cysu (CG5873, FBgn0038511). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:17425768..17446499. It has the cytological map location 90A6-90B1. Protein features are: Haem peroxidase; Haem peroxidase, animal type. Its molecular function is described by: peroxidase activity; heme binding. It is involved in the biological process described with: oxidation-reduction process; response to oxidative stress. 14 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; wing. The phenotypic classes of alleles include: fertile; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages.  "
FBgn0266421	RPA3	0.429777235	0.273712416	0.999936032	NA	RPA3	high	NA	NA	NA	"The gene Replication protein A3 is referred to in FlyBase by the symbol Dmel\RPA3 (CG15220, FBgn0266421). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:11615097..11615840. It has the cytological map location 10D1-10D3. Protein features are: Nucleic acid-binding, OB-fold; Replication factor A protein 3. Its molecular function is described by: DNA binding. It is involved in the biological process described with: neuronal stem cell population maintenance; DNA recombination; DNA replication; DNA repair. 6 alleles are reported. The phenotypes of these alleles manifest in: larval outer optic anlage; mesothoracic tergum; embryonic/larval neuroblast; ganglion mother cell; lamina anlage; medulla anlage. The phenotypic classes of alleles include: lethal; increased mortality; phenotype; increased mortality during development."
FBgn0034009	CG8155	0.430134045	0.301255722	0.999936032	NA	TBC1D25	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8155 (FBgn0034009). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:15317817..15322171. It has the cytological map location 51F5-51F6. Protein features are: Rab-GTPase-TBC domain. Its molecular function is described by: GTPase activator activity; Rab GTPase binding. It is involved in the biological process described with: intracellular protein transport; determination of adult lifespan; activation of GTPase activity; border follicle cell migration; regulation of GTPase activity; regulation of vesicle fusion. 5 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; border follicle cell; mesothoracic tergum. The phenotypic classes of alleles include: increased mortality during development; phenotype; visible; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, during early pupal stages.  "
FBgn0030744	CG9992	0.430242403	0.264428338	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9992 (FBgn0030744). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (2 unique). Gene sequence location is X:16381954..16384908. It has the cytological map location 14C2. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0025185	az2	0.430795384	0.30452255	0.999936032	NA	ZNF133;ZNF585A	low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene az2 is referred to in FlyBase by the symbol Dmel\az2 (CG1605, FBgn0025185). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:7510622..7512749. It has the cytological map location 43D1. Protein features are: MADF domain; Zinc finger C2H2-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: nucleic acid binding; zinc ion binding; transcription factor activity, sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated. 6 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0052791	DIP-alpha	0.431088236	0.270089398	0.999936032	NA	OPCML;NTM;LSAMP;IGLON5;NEGR1	moderate;moderate;high;low;low	NA	NA	NA	"The gene Dpr-interacting protein ‘± is referred to in FlyBase by the symbol Dmel\DIP-‘± (CG32791, FBgn0052791). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:3507245..3571649. It has the cytological map location 3D4-3D6. Protein features are: Immunoglobulin I-set; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold. Its molecular function is unknown. It is involved in the biological process described with: septate junction assembly; synapse organization. 16 alleles are reported. The phenotypes of these alleles manifest in: chaeta; trichogen cell. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; lethal; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0051159	mRRF2	0.431091428	0.303748185	0.999936032	NA	GFM2;GFM1	high;low	NA	NA	NA	"The gene mitochondrial ribosome recycling factor 2 is referred to in FlyBase by the symbol Dmel\mRRF2 (CG31159, FBgn0051159). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:22613686..22616622. It has the cytological map location 94B6. Protein features are: EF-G domain III/V-like; EFG, domain V; Elongation factor EFG, domain V-like; Elongation factor G, domain III; P-loop containing nucleoside triphosphate hydrolase; Ribosomal protein S5 domain 2-type fold; Ribosomal protein S5 domain 2-type fold, subgroup; Ribosome-releasing factor 2, mitochondrial; Small GTP-binding protein domain; Tr-type G domain, conserved site; Transcription factor, GTP-binding domain; Translation protein, beta-barrel domain. Its molecular function is described by: GTPase activity; GTP binding. It is involved in the biological process described with: ribosome disassembly; mitochondrial translation. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0035264	Oseg4	0.432230866	0.299883584	0.999936032	WDR35	WDR35	high	NA	NA	NA	"The gene Outer segment 4 is referred to in FlyBase by the symbol Dmel\Oseg4 (CG2069, FBgn0035264). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:1730993..1735767. It has the cytological map location 62B1. Protein features are: Anaphase-promoting complex subunit 4, WD40 domain; Tetratricopeptide-like helical domain; WD repeat protein 35; WD40 repeat; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: phosphatidylinositol binding. It is involved in the biological process described with: protein localization to cilium; cilium assembly; non-motile cilium assembly; intraciliary retrograde transport. 12 alleles are reported. The phenotypes of these alleles manifest in: Z disc; sarcomere; myofibril; ganglion mother cell; indirect flight muscle. The phenotypic classes of alleles include: neuroanatomy defective; partially lethal - majority die; lethal; flightless; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0050094	CG30094	0.432252577	0.303736958	0.999936032	NA	IGHMBP2	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG30094 (FBgn0050094). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:16142202..16142935. It has the cytological map location 52E10-52E11. Protein features are: Zinc finger, AN1-type. Its molecular function is described by: zinc ion binding. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, during late pupal stages, in adult male stages.  "
FBgn0031534	Snx1	0.432651805	0.233039192	0.999936032	SNX2	SNX2;SNX1;SNX30	high;moderate;moderate	NA	NA	NA	"The gene Sorting nexin 1 is referred to in FlyBase by the symbol Dmel\Snx1 (CG2774, FBgn0031534). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:3449683..3452106. It has the cytological map location 23F3. Protein features are: Arfaptin homology (AH) domain/BAR domain; Phox homologous domain; Sorting nexin Vps5-like, C-terminal. Its molecular function is described by: protein transporter activity; phosphatidylinositol-3-phosphate binding; phosphatidylinositol binding. It is involved in the biological process described with: retrograde transport, endosome to Golgi; endocytosis; vesicle organization; early endosome to Golgi transport. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0038037	Cyp9f2	0.433388827	0.208207856	0.999936032	NA	CYP3A4;TBXAS1;CYP3A43;CYP3A5;CYP3A7-CYP3A51P;CYP3A7	high;moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"The gene Cyp9f2 is referred to in FlyBase by the symbol Dmel\Cyp9f2 (CG11466, FBgn0038037). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:12403340..12406028. It has the cytological map location 87B9. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Its molecular function is described by: oxidoreductase activity; heme binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; iron ion binding. It is involved in the biological process described with: wing disc development; oxidation-reduction process. 6 alleles are reported. The phenotype of these alleles manifest in: wing margin. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during late larval stages, in adult male stages.  "
FBgn0035770	pst	0.433685858	0.208095737	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene pastrel is referred to in FlyBase by the symbol Dmel\pst (CG8588, FBgn0035770). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:7357275..7360263. It has the cytological map location 65F6-65F7. Protein features are: Domain of unknown function DUF4781. Its molecular function is described by: . It is involved in the biological process described with: olfactory learning; protein secretion; long-term memory; learning or memory. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: stress response defective; memory defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0265296	Dscam2	0.434525803	0.242396758	0.999936032	NA	DSCAM;DSCAML1	moderate;moderate	NA	transmembrane protein	NA	"The gene Down syndrome cell adhesion molecule 2 is referred to in FlyBase by the symbol Dmel\Dscam2 (CG42256, FBgn0265296). It is a protein_coding_gene from Drosophila melanogaster. It has 15 annotated transcripts and 15 polypeptides (all unique). Gene sequence location is 3L:7159199..7189931. It has the cytological map location 65E6. Protein features are: Down syndrome cell adhesion molecule; Fibronectin type III; Immunoglobulin I-set; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold. Its molecular function is described by: identical protein binding. It is involved in the biological process described with: neuron projection morphogenesis; homophilic cell adhesion via plasma membrane adhesion molecules. 14 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; lamina monopolar neuron L1; medulla. The phenotypic classes of alleles include: neuroanatomy defective; body color defective; viable."
FBgn0263260	sel	0.434898529	0.22152692	0.999936032	NA	CNPY2;CNPY1	high;moderate	NA	NA	NA	"The gene seele is referred to in FlyBase by the symbol Dmel\sel (CG12918, FBgn0263260). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:10050862..10052167. It has the cytological map location 46D9. Protein features are: Domain of unknown function DUF3456. Its molecular function is described by: chaperone binding. It is involved in the biological process described with: regulation of protein processing; polarity specification of dorsal/ventral axis; maternal specification of dorsal/ventral axis, oocyte, germ-line encoded; tissue development; regulation of protein secretion; enzyme linked receptor protein signaling pathway; chaperone-mediated protein folding. 10 alleles are reported. The phenotypes of these alleles manifest in: denticle belt; filzkorper; male accessory gland secondary cell. The phenotypic classes of alleles include: some die during embryonic stage; decreased cell number; female sterile; viable; lethal - all die before end of embryonic stage."
FBgn0052069	CG32069	0.434905747	0.243267184	0.999936032	NA	IER3IP1	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32069 (FBgn0052069). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:11062131..11062614. It has the cytological map location 68A3. Protein features are: Yos1-like. Its molecular function is unknown. It is involved in the biological process described with: ER to Golgi vesicle-mediated transport. 5 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; embryonic/larval neuroblast. The phenotypic classes of alleles include: increased mortality during development; phenotype; increased mortality; some die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0030082	HP1b	0.435240177	0.252803169	0.999936032	CBX1	CBX1;CBX3;CBX5	high;moderate;moderate	Chromatin regulation	NA	NA	"The gene Heterochromatin Protein 1b is referred to in FlyBase by the symbol Dmel\HP1b (CG7041, FBgn0030082). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is X:9081063..9082746. It has the cytological map location 8C4. Protein features are: Chromo domain; Chromo domain subgroup; Chromo domain, conserved site; Chromo domain-like; Chromo shadow domain; Chromo/chromo shadow domain. Its molecular function is described by: chromatin binding. It is involved in the biological process described with: negative regulation of heterochromatin assembly; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter. 9 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: partially lethal - majority die; visible; viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0260795	NaPi-III	0.435366967	0.268087775	0.999936032	NA	SLC20A1;SLC20A2	high;moderate	NA	transmembrane protein	NA	"The gene Na<sup>+</sup>-dependent inorganic phosphate cotransporter type III is referred to in FlyBase by the symbol Dmel\NaPi-III (CG42575, FBgn0260795). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:11123348..11134663. It has the cytological map location 68A7. Protein features are: Phosphate transporter; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: inorganic phosphate transmembrane transporter activity; sodium-dependent phosphate transmembrane transporter activity; sodium:inorganic phosphate symporter activity. It is involved in the biological process described with: sodium-dependent phosphate transport. 18 alleles are reported. The phenotypes of these alleles manifest in: sarcomere; myofibril; Z disc. The phenotypic classes of alleles include: viable; flightless. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0051004	mesh	0.435598563	0.208225549	0.999936032	NA	SUSD2	high	NA	transmembrane protein	NA	"The gene mesh is referred to in FlyBase by the symbol Dmel\mesh (CG31004, FBgn0051004). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is 3R:31178389..31195762. It has the cytological map location 100B5. Protein features are: AMOP domain; Immunoglobulin E-set; Immunoglobulin-like fold; NIDO domain; Sushi/SCR/CCP domain; von Willebrand factor, type D domain. Its molecular function is described by: protein binding. It is involved in the biological process described with: cell-matrix adhesion; smooth septate junction assembly. 6 alleles are reported. The phenotypes of these alleles manifest in: smooth septate junction; embryonic/larval midgut. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; short lived; some die during first instar larval stage; viable; lethal - all die before end of first instar larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages.  "
FBgn0034612	CG10505	0.435874866	0.26638314	0.999936032	NA	ABCC1;ABCC4;ABCC3;ABCC8;ABCC9;ABCC6;ABCC10;ABCC2;CFTR;ABCC12;ABCC11;ABCC5	moderate;moderate;moderate;low;low;low;low;low;moderate;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10505 (FBgn0034612). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:21285248..21290343. It has the cytological map location 57D7-57D8. Protein features are: AAA+ ATPase domain; ABC transporter type 1, transmembrane domain; ABC transporter, conserved site; ABC transporter-like; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: ATP binding; ATPase activity, coupled to transmembrane movement of substances. It is involved in the biological process described with: transmembrane transport; response to copper ion; response to zinc ion. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during late larval stages.  "
FBgn0051632	sens-2	0.436128873	0.24656638	0.999936032	NA	GFI1B;GFI1	high;moderate	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene senseless-2 is referred to in FlyBase by the symbol Dmel\sens-2 (CG31632, FBgn0051632). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:6821934..6838995. It has the cytological map location 27B4. Protein features are: Zinc finger C2H2-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: nucleic acid binding. The biological processes in which it is involved are not known. 7 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 06-24 hour embryonic stages.  "
FBgn0050031	CG30031	0.436142872	0.218642202	0.999936032	NA	PRSS36;PRSS53;PRSS45;PRSS8;PRSS27;PRSS22;TPSG1;PRSS33;PRSS38;CMA1;PRSS1;PRSS3	low;low;low;low;low;low;low;low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG30031 (FBgn0050031). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:11350811..11351621. It has the cytological map location 47F4. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period.  "
FBgn0025558	CG4101	0.436271969	0.284647105	0.999936032	NA	MANBAL	high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4101 (FBgn0025558). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:16612486..16612950. It has the cytological map location 73B1. Protein features are: Uncharacterised protein family UPF0239. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; some die during pupal stage; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0034312	CG10916	0.436348095	0.236774507	0.999936032	NA	RNF2;BRCA1;RING1;PCGF1	low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10916 (FBgn0034312). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:18173669..18175725. It has the cytological map location 55B11-55B12. Protein features are: DM9 repeat; Domain of unknown function DUF3421; Zinc finger, RING-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: ubiquitin-protein transferase activity; zinc ion binding. It is involved in the biological process described with: intracellular signal transduction; determination of adult lifespan; protein ubiquitination. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable; long lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult male stages.  "
FBgn0031515	CG9664	0.436382064	0.245724029	0.999936032	NA	ABCG1;ABCG4;ABCG8	moderate;moderate;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9664 (FBgn0031515). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 2L:3291245..3294706. It has the cytological map location 23E1. Protein features are: AAA+ ATPase domain; ABC transporter-like; ABC-2 type transporter; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: cholesterol transporter activity; ATP binding; ATPase activity, coupled to transmembrane movement of substances; sterol-transporting ATPase activity. It is involved in the biological process described with: transmembrane transport; olfactory behavior. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable; lethal - all die during P-stage; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during late larval stages, during late pupal stages.  "
FBgn0028526	CG15293	0.436570166	0.298356736	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15293 (FBgn0028526). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:14108057..14109447. It has the cytological map location 34F4. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0037974	CG12224	0.437883316	0.285747549	0.999936032	NA	SRM;KCNAB2	low;low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG12224 (FBgn0037974). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:11980704..11982622. It has the cytological map location 87A4. Protein features are: NADP-dependent oxidoreductase domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during early pupal stages.
FBgn0015222	Fer1HCH	0.438031339	0.202985057	0.999936032	NA	FTH1;FTHL17;FTMT	moderate;moderate;moderate	NA	NA	NA	"The gene Ferritin 1 heavy chain homologue is referred to in FlyBase by the symbol Dmel\Fer1HCH (CG2216, FBgn0015222). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (5 unique). Gene sequence location is 3R:30385573..30388178. It has the cytological map location 99F2. Protein features are: Ferritin; Ferritin-like diiron domain; Ferritin-like superfamily; Ferritin-related; Ferritin/DPS protein domain. Its molecular function is described by: iron ion binding; ferrous iron binding; ferric iron binding. It is involved in the biological process described with: post-embryonic development; sleep; response to fungus; iron ion import across plasma membrane; detoxification of iron ion; cellular iron ion homeostasis; cell proliferation; intracellular sequestering of iron ion. 49 alleles are reported. The phenotypes of these alleles manifest in: somatic cell; organ system; central nervous system; cell part; adult integumentary system; larva; cell cluster organ; germline cell; thoracic segment; developing material anatomical entity; brain; germarium; trichogen cell; plasma membrane bounded cell projection; multicellular structure; germ band. The phenotypic classes of alleles include: increased mortality; developmental rate defective; increased mortality during development; viable; lethal - all die during P-stage; phenotype; some die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Very high expression at all stages of development.  "
FBgn0033871	CG13339	0.438055007	0.272511936	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13339 (FBgn0033871). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:13824858..13825572. It has the cytological map location 50C6. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0011746	ana	0.438055682	0.29495483	0.999936032	NA	NA	NA	NA	NA	NA	"The gene anachronism is referred to in FlyBase by the symbol Dmel\ana (CG8084, FBgn0011746). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 2R:9062295..9077554. It has the cytological map location 45A1. Its molecular function is unknown. The biological processes in which it is involved are not known. 17 alleles are reported. The phenotypes of these alleles manifest in: thoracic neuroblast; neuroblast; type I neuroblast. The phenotypic classes of alleles include: wild-type; smell perception defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult male stages.  "
FBgn0032002	CG8353	0.438198609	0.232869376	0.999936032	NA	CDA	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8353 (FBgn0032002). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:8214045..8215239. It has the cytological map location 28F3. Protein features are: APOBEC/CMP deaminase, zinc-binding; Cytidine and deoxycytidylate deaminase domain; Cytidine deaminase, homotetrameric; Cytidine deaminase-like. Its molecular function is described by: cytidine deaminase activity; zinc ion binding. It is involved in the biological process described with: cytidine deamination. 5 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period.  "
FBgn0020236	ATPCL	0.438380556	0.217705966	0.999936032	NA	ACLY	high	NA	NA	NA	"The gene ATP citrate lyase is referred to in FlyBase by the symbol Dmel\ATPCL (CG8322, FBgn0020236). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 2R:15993531..16001290. It has the cytological map location 52D9-52D11. Protein features are: ATP-citrate lyase/succinyl-CoA ligase; ATP-citrate lyase/succinyl-CoA ligase, active site; ATP-citrate lyase/succinyl-CoA ligase, conserved site; ATP-citrate synthase; ATP-citrate synthase, citrate-binding domain; ATP-grasp fold, succinyl-CoA synthetase-type; Citrate synthase; Citrate synthase-like, large alpha subdomain; Citrate synthase-like, small alpha subdomain; CoA-binding; FAM91, C-terminal domain; FAM91, N-terminal domain; NAD(P)-binding domain; Succinyl-CoA synthetase, beta subunit, conserved site; Succinyl-CoA synthetase-like. Its molecular function is described by: cofactor binding; ATP citrate synthase activity. It is involved in the biological process described with: citrate metabolic process; fatty acid biosynthetic process; acetyl-CoA biosynthetic process; regulation of glucose metabolic process. 15 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; egg chamber; trichogen cell. The phenotypic classes of alleles include: partially lethal - majority die; increased cell death; some die during pupal stage; lethal; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0032748	CG10492	0.438742475	0.268545476	0.999936032	NA	ZCCHC2	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10492 (FBgn0032748). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:19054078..19058821. It has the cytological map location 37B12. Protein features are: Zinc finger, CCHC-type. Its molecular function is described by: nucleic acid binding; zinc ion binding. The biological processes in which it is involved are not known. 5 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: body color defective; fertile; viable; visible; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0031914	CG5973	0.438889732	0.218567381	0.999936032	NA	TTPAL	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5973 (FBgn0031914). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (1 unique). Gene sequence location is 2L:7437492..7445882. It has the cytological map location 27F4-28A1. Protein features are: CRAL-TRIO lipid binding domain; CRAL/TRIO, N-terminal domain; Cellular retinaldehyde binding/alpha-tocopherol transport. Its molecular function is described by: transporter activity. It is involved in the biological process described with: sleep; transport. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; some die during pupal stage; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, during early pupal stages.  "
FBgn0030294	Pa1	0.438980085	0.253748621	0.999936032	NA	PAGR1	high	NA	NA	NA	"The gene PTIP associated 1 is referred to in FlyBase by the symbol Dmel\Pa1 (CG11750, FBgn0030294). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:11359236..11360929. It has the cytological map location 10B5. Protein features are: PTIP-associated protein 1. Its molecular function is described by: . It is involved in the biological process described with: histone H3-K4 methylation. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, during early pupal stages, in adult female stages.  "
FBgn0037702	CG8176	0.439400423	0.247015465	0.999936032	NA	FCHO2;FCHO1;SGIP1;GAS7	high;moderate;moderate;moderate	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG8176 (FBgn0037702). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is 3R:9516007..9527237. It has the cytological map location 85D19. Protein features are: Arfaptin homology (AH) domain/BAR domain; F-BAR domain; FCH domain; Mu homology domain; Muniscin C-terminal. Its molecular function is described by: AP-2 adaptor complex binding; phospholipid binding. It is involved in the biological process described with: clathrin-dependent endocytosis. 8 alleles are reported. The phenotype of these alleles manifest in: tormogen cell. The phenotypic classes of alleles include: partially lethal; viable; visible; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0011672	Mvl	0.440193586	0.211210504	0.999936032	SLC11A2	SLC11A2;SLC11A1	high;moderate	NA	transmembrane protein	NA	"The gene Malvolio is referred to in FlyBase by the symbol Dmel\Mvl (CG3671, FBgn0011672). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (4 unique). Gene sequence location is 3R:21051383..21060800. It has the cytological map location 93B7-93B8. Protein features are: NRAMP family. Its molecular function is described by: symporter activity; iron ion transmembrane transporter activity; manganese ion transmembrane transporter activity; copper ion transmembrane transporter activity. It is involved in the biological process described with: transition metal ion homeostasis; transition metal ion transport; divalent metal ion transport; multicellular organismal iron ion homeostasis; positive regulation of iron ion transmembrane transport; copper ion homeostasis; sensory perception of sweet taste; viral entry into host cell; copper ion import; iron assimilation. 26 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: sensory perception defective; phenotype; increased mortality; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.  "
FBgn0031805	CG9505	0.441024134	0.283673055	0.999936032	NA	ECE2;ECE1;KEL;ECEL1	moderate;moderate;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9505 (FBgn0031805). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:6367882..6370190. It has the cytological map location 26C4. Protein features are: Metallopeptidase, catalytic domain; Peptidase M13; Peptidase M13, C-terminal domain; Peptidase M13, N-terminal domain. Its molecular function is described by: metalloendopeptidase activity. It is involved in the biological process described with: proteolysis. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0040069	vanin-like	0.441045887	0.211966916	0.999936032	NA	BTD;VNN2;VNN1;VNN3	high;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene vanin-like is referred to in FlyBase by the symbol Dmel\vanin-like (CG32754, FBgn0040069). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:6200188..6202559. It has the cytological map location 5E1. Protein features are: Biotinidase-like, eukaryotic; Carbon-nitrogen hydrolase. Its molecular function is described by: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; hydrolase activity; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides. It is involved in the biological process described with: nitrogen compound metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed during early larval stages.  "
FBgn0261090	Sytbeta	0.441454971	0.290903713	0.999936032	NA	SYT6;SYT10;SYT9;SYT3	high;moderate;moderate;high	NA	transmembrane protein	NA	"The gene Synaptotagmin ‘_ is referred to in FlyBase by the symbol Dmel\Syt‘_ (CG42333, FBgn0261090). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:15014695..15064977. It has the cytological map location 71B1-71B2. Protein features are: C2 domain; Synaptotagmin. Its molecular function is described by: calcium-dependent phospholipid binding; syntaxin binding; calcium ion binding; clathrin binding. It is involved in the biological process described with: synaptic vesicle exocytosis; vesicle fusion; calcium ion-regulated exocytosis of neurotransmitter; regulation of calcium ion-dependent exocytosis. 18 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal - majority die; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0259964	Sfp33A3	0.441495785	0.214889205	0.999936032	NA	SPINK2	moderate	NA	NA	NA	"The gene Seminal fluid protein 33A3 is referred to in FlyBase by the symbol Dmel\Sfp33A3 (CG42474, FBgn0259964). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:11839912..11840329. It has the cytological map location 33A3. Protein features are: Kazal domain. Its molecular function is described by: enzyme inhibitor activity. It is involved in the biological process described with: multicellular organism reproduction; negative regulation of catalytic activity. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed in adult male stages.  "
FBgn0027548	nito	0.441545942	0.27245416	0.999936032	NA	RBM15B;RBM15	high;moderate	NA	NA	NA	"The gene spenito is referred to in FlyBase by the symbol Dmel\nito (CG2910, FBgn0027548). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:7962463..7969805. It has the cytological map location 43F8-43F9. Protein features are: RNA recognition motif domain; SPOC-like, C-terminal domain; Spen paralogue and orthologue SPOC, C-terminal; Spen paralogue/orthologue C-terminal, metazoa. Its molecular function is described by: mRNA binding; nucleic acid binding. It is involved in the biological process described with: negative regulation of stem cell differentiation; regulation of alternative mRNA splicing, via spliceosome; positive regulation of gene expression; mRNA splicing, via spliceosome; positive regulation of Wnt signaling pathway; wing disc pattern formation; compound eye development. 19 alleles are reported. The phenotypes of these alleles manifest in: larva; cell part; plasma membrane bounded cell projection; metatarsus of male prothoracic leg; pupa; sensory system neuron; cell projection; adult external abdomen; prepupa; eye disc; optic lobe neuron; cell. The phenotypic classes of alleles include: some die during P-stage; increased mortality; phenotype; some die during larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0023535	arg	0.441923558	0.193858604	0.999936032	NA	ARG1;ARG2	high;high	NA	NA	NA	"The gene arginase is referred to in FlyBase by the symbol Dmel\arg (CG18104, FBgn0023535). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:509435..528028. It has the cytological map location 1B7-1B8. Protein features are: Arginase; Ureohydrolase. Its molecular function is described by: arginase activity; metal ion binding. It is involved in the biological process described with: arginine catabolic process to ornithine. 42 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal - majority die; partially lethal; some die during pupal stage; fertile; lethal - all die during P-stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0266810	CR45272	0.4419875	0.264685566	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45272 (FBgn0266810). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2R:17121095..17124636. It has the cytological map location 53F12. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0035176	CG13905	0.442454617	0.292414689	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG13905 (FBgn0035176). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:902898..903810. It has the cytological map location 61D4. Protein features are: Insect allergen-related. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed during early pupal stages.
FBgn0038396	CG5013	0.442670697	0.254076219	0.999936032	METTL23	METTL23	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG5013 (FBgn0038396). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:16049670..16050693. It has the cytological map location 89B1. Protein features are: Lysine methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase. Its molecular function is described by: protein-lysine N-methyltransferase activity. It is involved in the biological process described with: peptidyl-lysine trimethylation. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.
FBgn0266632	CR45139	0.4429102	0.224688373	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45139 (FBgn0266632). It is a non_protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts. Gene sequence location is 2R:3943429..3949757. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0032399	CG6785	0.443428859	0.264118594	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6785 (FBgn0032399). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:12041054..12045200. It has the cytological map location 33B10-33B11. Protein features are: WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 21 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum. The phenotypic classes of alleles include: viable; visible; body color defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages, during early larval stages.  "
FBgn0035679	CG10467	0.443508371	0.204021082	0.999936032	NA	GALM	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10467 (FBgn0035679). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:6093204..6094747. It has the cytological map location 65A6. Protein features are: Aldose 1-/Glucose-6-phosphate 1-epimerase; Aldose 1-epimerase; Aldose 1-epimerase, conserved site; Galactose mutarotase-like domain; Glycoside hydrolase-type carbohydrate-binding. Its molecular function is described by: aldose 1-epimerase activity; carbohydrate binding. It is involved in the biological process described with: glucose metabolic process; galactose catabolic process via UDP-galactose. 9 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0033798	CG15870	0.443613702	0.233423332	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15870 (FBgn0033798).The gene has a gene model, but the supporting evidence is inconclusive. It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:13163363..13163948. It has the cytological map location 49F4. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed during late larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0032087	CG9568	0.443872006	0.198030781	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9568 (FBgn0032087). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:9010583..9011358. It has the cytological map location 29F7. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages, during late larval stages.  "
FBgn0001230	Hsp68	0.443945394	0.253981365	0.999936032	HSPA1A;HSPA1B	HSPA1A;HSPA1B;HSPA1L;HSPA6;HSPA8;HSPA2;HSPA5	high;moderate;moderate;moderate;low;low;low	NA	NA	NA	"The gene Heat shock protein 68 is referred to in FlyBase by the symbol Dmel\Hsp68 (CG5436, FBgn0001230). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:24055080..24057310. It has the cytological map location 95D11. Protein features are: Heat shock protein 70 family; Heat shock protein 70, conserved site; Heat shock protein 70kD, C-terminal domain; Heat shock protein 70kD, peptide-binding domain. Its molecular function is described by: unfolded protein binding. It is involved in the biological process described with: response to starvation; determination of adult lifespan; protein folding. 14 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; ganglion mother cell; embryonic/larval neuroblast. The phenotypic classes of alleles include: phenotype; increased mortality during development; visible; increased mortality; stress response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late larval stages, at stages throughout the pupal period.  "
FBgn0038608	WRNexo	0.443978821	0.183985343	0.999936032	NA	WRN	high	NA	NA	NA	"The gene WRN exonuclease is referred to in FlyBase by the symbol Dmel\WRNexo (CG7670, FBgn0038608). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3R:18364244..18366162. It has the cytological map location 91A3. Protein features are: 3'-5' exonuclease domain; Ribonuclease H-like domain. Its molecular function is described by: double-stranded DNA 3'-5' exodeoxyribonuclease activity; nucleic acid binding; 3'-5' exonuclease activity; single-stranded DNA 3'-5' exodeoxyribonuclease activity. It is involved in the biological process described with: replication fork protection; negative regulation of mitotic recombination; DNA catabolic process, exonucleolytic. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: phenotype; increased mortality during development; increased mortality; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0053229	CG33229	0.444168424	0.214990859	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG33229 (FBgn0053229). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:223852..225605. It has the cytological map location 61B2. Its molecular function is described by: . It is involved in the biological process described with: . 6 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0037782	Npc2d	0.44523241	0.199442285	0.999936032	NA	NPC2	moderate	NA	NA	NA	"The gene Niemann-Pick type C-2d is referred to in FlyBase by the symbol Dmel\Npc2d (CG12813, FBgn0037782). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:10055356..10056083. It has the cytological map location 85F8. Protein features are: Immunoglobulin E-set; MD-2-related lipid-recognition domain; ML domain, Npc2 like. Its molecular function is described by: sterol binding. It is involved in the biological process described with: sterol transport; intracellular cholesterol transport. 2 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: short lived; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period, in adult male stages.  "
FBgn0037299	Vps37B	0.445665888	0.219340916	0.999936032	NA	VPS37B;VPS37C;VPS37D;VPS37A	high;moderate;moderate;low	NA	NA	NA	"The gene Vacuolar protein sorting 37B is referred to in FlyBase by the symbol Dmel\Vps37B (CG1115, FBgn0037299). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:5226158..5227526. It has the cytological map location 82F6. Protein features are: Modifier of rudimentary, Modr. Its molecular function is described by: . It is involved in the biological process described with: endosome transport via multivesicular body sorting pathway. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 06-12 hour embryonic stages, during early pupal stages.  "
FBgn0031741	CG11034	0.446201746	0.200510493	0.999936032	DPP4	DPP4;FAP;DPP10;DPP6	high;moderate;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11034 (FBgn0031741). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:5805395..5809063. It has the cytological map location 25F5. Protein features are: Alpha/Beta hydrolase fold; Dipeptidylpeptidase IV, N-terminal domain; Peptidase S9, prolyl oligopeptidase, catalytic domain. Its molecular function is described by: serine-type peptidase activity; dipeptidyl-peptidase activity. It is involved in the biological process described with: proteolysis. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed during late larval stages.  "
FBgn0053108	CG33108	0.446527744	0.26650206	0.999936032	NA	C19orf54	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG33108 (FBgn0053108). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:23995659..23997544. It has the cytological map location 95D5. Its molecular function is described by: . It is involved in the biological process described with: . 6 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: body color defective; fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0025630	Rtca	0.447619938	0.260054984	0.999936032	NA	RTCA	high	NA	NA	NA	"The gene RNA 3'-terminal phosphate cyclase is referred to in FlyBase by the symbol Dmel\Rtca (CG4061, FBgn0025630). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:2072413..2074890. It has the cytological map location 2C10. Protein features are: RNA 3'-terminal phosphate cyclase; RNA 3'-terminal phosphate cyclase domain; RNA 3'-terminal phosphate cyclase type 1; RNA 3'-terminal phosphate cyclase, insert domain; RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta. Its molecular function is described by: RNA-3'-phosphate cyclase activity. It is involved in the biological process described with: negative regulation of axon regeneration; RNA processing. 11 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: increased cell growth; decreased cell growth; fertile; viable; male sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, during early pupal stages.  "
FBgn0031032	CG14204	0.44805109	0.252456966	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14204 (FBgn0031032). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:19583617..19587057. It has the cytological map location 18D3. Protein features are: Acyltransferase 3; Nose resistant-to-fluoxetine protein, N-terminal. Its molecular function is described by: transferase activity, transferring acyl groups other than amino-acyl groups. It is involved in the biological process described with: chaeta development; wing disc development. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0037622	CG8202	0.448410732	0.2634941	0.999936032	C16orf62	C16orf62	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG8202 (FBgn0037622). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:8732091..8735837. It has the cytological map location 85A9. Protein features are: Armadillo-like helical; UPF0505 family. Its molecular function is described by: . It is involved in the biological process described with: . 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0266212	CR44907	0.448480056	0.151763363	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44907 (FBgn0266212). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2L:20068793..20069318. It has the cytological map location 38B2. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0015577	alpha-Est9	0.448830687	0.223655316	0.999936032	NA	BCHE;CES4A;CES2;NLGN2;CES5A;CES1;CEL;NLGN4X;NLGN1;NLGN3;NLGN4Y;CES3	low;low;low;low;low;low;low;low;low;low;low;low	NA	NA	NA	"The gene ‘±-Esterase-9 is referred to in FlyBase by the symbol Dmel\‘±-Est9 (CG1128, FBgn0015577). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:7493921..7505098. It has the cytological map location 84D9. Protein features are: Alpha/Beta hydrolase fold; Carboxylesterase type B, active site; Carboxylesterase, type B; Cholinesterase. Its molecular function is described by: cholinesterase activity. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0086895	pea	0.448844849	0.285566601	0.999936032	NA	DHX8;DHX16;DHX15;DHX38;DHX33	high;low;low;low;low	NA	NA	NA	"The gene peanuts is referred to in FlyBase by the symbol Dmel\pea (CG8241, FBgn0086895). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:14153153..14157106. It has the cytological map location 50E1. Protein features are: DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site; Domain of unknown function DUF1605; Helicase superfamily 1/2, ATP-binding domain; Helicase, C-terminal; Helicase-associated domain; Nucleic acid-binding, OB-fold; P-loop containing nucleoside triphosphate hydrolase; RNA-binding domain, S1; S1 domain. Its molecular function is described by: ATP-dependent RNA helicase activity; RNA binding. It is involved in the biological process described with: spermatid development; regulation of alternative mRNA splicing, via spliceosome; mRNA splicing, via spliceosome; ventral cord development; chromatin organization; oogenesis. 12 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; embryonic/larval neuroblast; nurse cell; spliceosomal complex; chromatin; egg chamber; apterous-expressing neuron of the lateral cluster of the thorax Ap4. The phenotypic classes of alleles include: increased mortality; lethal; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0032387	CG16965	0.449822462	0.201646338	0.999936032	ATHL1	PGGHG	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG16965 (FBgn0032387). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:11981591..11984380. It has the cytological map location 33B5. Protein features are: Glycoside hydrolase, family 65, central catalytic; Six-hairpin glycosidase-like. Its molecular function is described by: hydrolase activity. It is involved in the biological process described with: carbohydrate metabolic process. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 06-12 hour embryonic stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0267664	CR46002	0.450987038	0.269137096	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR46002 (FBgn0267664). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3L:509297..509890. It has the cytological map location 61C3. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0033683	CG18343	0.451126993	0.204489903	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG18343 (FBgn0033683). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:12138695..12139324. It has the cytological map location 48E2. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed during late larval stages, during early pupal stages, in adult male stages.  "
FBgn0013307	Odc1	0.451559809	0.255748801	0.999936032	NA	ODC1;AZIN1;AZIN2	high;moderate;moderate	NA	NA	NA	"The gene Ornithine decarboxylase 1 is referred to in FlyBase by the symbol Dmel\Odc1 (CG8721, FBgn0013307). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:8004824..8006672. It has the cytological map location 44A2. Protein features are: Alanine racemase/group IV decarboxylase, C-terminal; Orn/DAP/Arg decarboxylase 2, C-terminal; Orn/DAP/Arg decarboxylase 2, N-terminal; Orn/DAP/Arg decarboxylase 2, conserved site; Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site; Ornithine decarboxylase; Ornithine/DAP/Arg decarboxylase; PLP-binding barrel. Its molecular function is described by: ornithine decarboxylase activity. It is involved in the biological process described with: putrescine biosynthetic process from ornithine. 7 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum; chaeta. The phenotypic classes of alleles include: viable; visible; delayed aging; body color defective; memory defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0026602	Ady43A	0.451646927	0.262423751	0.999936032	NA	ADK	moderate	NA	NA	NA	"The gene Ady43A is referred to in FlyBase by the symbol Dmel\Ady43A (CG1851, FBgn0026602). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:7243024..7245776. It has the cytological map location 43A1-43A2. Protein features are: Carbohydrate kinase PfkB; Carbohydrate/puine kinase, PfkB, conserved site; Ribokinase-like. Its molecular function is described by: adenosine kinase activity. It is involved in the biological process described with: adenosine salvage. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal - majority die; lethal - all die during embryonic stage; some die during pupal stage; fertile; lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the pupal period.  "
FBgn0038974	CG5377	0.451809116	0.23182594	0.999936032	BPHL	BPHL	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG5377 (FBgn0038974). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:22466905..22468157. It has the cytological map location 94A16. Protein features are: Alpha/Beta hydrolase fold; Alpha/beta hydrolase fold-1. Its molecular function is described by: hydrolase activity. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed during early larval stages.
FBgn0026324	Taf10b	0.451886524	0.225406156	0.999936032	NA	TAF10	high	DNA-binding with transcription factor activity	NA	NA	"The gene TBP-associated factor 10b is referred to in FlyBase by the symbol Dmel\Taf10b (CG3069, FBgn0026324). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:2767286..2767845. It has the cytological map location 23A5. Protein features are: Transcription initiation factor TFIID, 23-30kDa subunit. Its molecular function is described by: protein binding; transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly; histone acetyltransferase activity. It is involved in the biological process described with: transcription initiation from RNA polymerase II promoter; histone H3 acetylation. 8 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderately high expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0034758	CG13510	0.451993822	0.191184661	0.999936032	NA	LITAF	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13510 (FBgn0034758). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:22657901..22661389. It has the cytological map location 58F4. Protein features are: LPS-induced tumour necrosis factor alpha factor. Its molecular function is described by: . It is involved in the biological process described with: cold acclimation. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; flightless. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0032382	Mal-B2	0.45208631	0.278090907	0.999936032	SLC3A1	SLC3A1;SLC3A2	high;low	NA	NA	NA	"The gene Maltase B2 is referred to in FlyBase by the symbol Dmel\Mal-B2 (CG14935, FBgn0032382). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:11849958..11852881. It has the cytological map location 33A4. Protein features are: Glycoside hydrolase superfamily; Glycosyl hydrolase, family 13, catalytic domain. Its molecular function is described by: catalytic activity. It is involved in the biological process described with: carbohydrate metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal - all die during P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0029079	icln	0.453085657	0.26577413	0.999936032	NA	CLNS1A	high	NA	NA	NA	"The gene icln is referred to in FlyBase by the symbol Dmel\icln (CG4924, FBgn0029079). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:17590964..17591881. It has the cytological map location 54C12. Protein features are: ICln. Its molecular function is unknown. It is involved in the biological process described with: chloride transport; cell volume homeostasis; spliceosomal snRNP assembly. 5 alleles are reported. The phenotype of these alleles manifest in: wing blade. The phenotypic classes of alleles include: increased mortality during development; flight defective; phenotype; increased mortality; locomotor behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0263019	CR43314	0.453817398	0.207407561	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR43314 (FBgn0263019). It is a non_protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts. Gene sequence location is 2L:11952200..11971094. It has the cytological map location 33B2-33B3. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0053120	CG33120	0.453819021	0.243845828	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG33120 (FBgn0053120). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:18841400..18844579. It has the cytological map location 37B1. Protein features are: O-acyltransferase WSD1, C-terminal. Its molecular function is described by: diacylglycerol O-acyltransferase activity; long-chain-alcohol O-fatty-acyltransferase activity. It is involved in the biological process described with: triglyceride biosynthetic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during late larval stages.  "
FBgn0267778	CR46109	0.454070106	0.197405583	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR46109 (FBgn0267778). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3R:29745209..29746083. It has the cytological map location 99B10. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0035298	SCOT	0.454560401	0.205352752	0.999936032	NA	OXCT1;OXCT2	high;moderate	NA	NA	NA	"The gene Succinyl-CoA:3-ketoacid CoA transferase is referred to in FlyBase by the symbol Dmel\SCOT (CG1140, FBgn0035298). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3L:1963143..1966805. It has the cytological map location 62B11-62B12. Protein features are: 3-oxoacid CoA-transferase; 3-oxoacid CoA-transferase, subunit A; 3-oxoacid CoA-transferase, subunit B; Coenzyme A transferase active site; Coenzyme A transferase binding site; Coenzyme A transferase family I. Its molecular function is described by: 3-oxoacid CoA-transferase activity. It is involved in the biological process described with: ketone body catabolic process. 11 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: fertile; body color defective; visible; viable; flight defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, during early larval stages.  "
FBgn0037975	CG3397	0.454682189	0.278295297	0.999936032	NA	SRM;KCNAB1	low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3397 (FBgn0037975). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:11983098..11984541. It has the cytological map location 87A4. Protein features are: Aldo/keto reductase; NADP-dependent oxidoreductase domain. Its molecular function is described by: oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. 5 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0037698	CG16779	0.454686885	0.258087031	0.999936032	NA	ELMSAN1;TRERF1;ZNF541	high;moderate;moderate	DNA-binding with transcription factor activity(Myb_DNA-binding|zf-C2H2)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG16779 (FBgn0037698). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is 3R:9461084..9493677. It has the cytological map location 85D17-85D18. Protein features are: ELM2 domain; Homeobox domain-like; SANT domain; SANT/Myb domain; Tetratricopeptide-like helical domain; Zinc finger C2H2-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: transcription factor activity, sequence-specific DNA binding; transcription regulatory region DNA binding; transcription factor binding. It is involved in the biological process described with: regulation of transcription from RNA polymerase II promoter. 9 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: lethal; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.  "
FBgn0038980	Octbeta1R	0.454686885	0.258087031	0.999936032	NA	HTR4;TAAR6;TAAR8;TAAR9;TAAR5;TAAR1;TAAR2;TAAR3	high;moderate;moderate;moderate;moderate;moderate;moderate;moderate	NA	transmembrane protein	GPCR	"The gene Octopamine ‘_1 receptor is referred to in FlyBase by the symbol Dmel\Oct‘_1R (CG6919, FBgn0038980). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 3R:22497215..22520078. It has the cytological map location 94B1-94B2. Protein features are: Adrenoceptor family; G protein-coupled receptor, rhodopsin-like; GPCR, rhodopsin-like, 7TM. Its molecular function is described by: G-protein coupled amine receptor activity; octopamine receptor activity; adrenergic receptor activity. It is involved in the biological process described with: adenylate cyclase-modulating G-protein coupled receptor signaling pathway; negative regulation of synaptic growth at neuromuscular junction; positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway; G-protein coupled receptor signaling pathway; adenylate cyclase-activating G-protein coupled receptor signaling pathway. 15 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval neuromuscular junction; type I bouton; type II bouton. The phenotypic classes of alleles include: locomotor behavior defective; neuroanatomy defective; fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0035903	CG6765	0.455816538	0.207508194	0.999936032	NA	ZBTB9	low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6765 (FBgn0035903). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:8512767..8518738. It has the cytological map location 66D5. Protein features are: BTB/POZ domain; SKP1/BTB/POZ domain; Zinc finger C2H2-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: nucleic acid binding. It is involved in the biological process described with: regulation of transcription from RNA polymerase II promoter. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages.  "
FBgn0004882	orb	0.457010306	0.22468467	0.999936032	NA	CPEB1	high	NA	NA	NA	"The gene oo18 RNA-binding protein is referred to in FlyBase by the symbol Dmel\orb (CG10868, FBgn0004882). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (4 unique). Gene sequence location is 3R:23260610..23280856. It has the cytological map location 94E9. Protein features are: CPEB-1, RNA recognition motif 1; Cytoplasmic polyadenylation element-binding protein; Cytoplasmic polyadenylation element-binding protein, ZZ domain; RNA recognition motif domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: ribosome binding; translation factor activity, RNA binding; mRNA binding; mRNA 3'-UTR binding; translation repressor activity, nucleic acid binding; protein binding. It is involved in the biological process described with 16 unique terms, many of which group under: negative regulation of cellular protein metabolic process; germarium-derived egg chamber formation; cell fate commitment; heterocycle metabolic process; RNA polyadenylation; negative regulation of biological process; macromolecule localization; RNA 3'-end processing; tissue development; pole plasm RNA localization. 39 alleles are reported. The phenotypes of these alleles manifest in: germline cyst; egg; embryo; oocyte; mesothoracic tergum; synaptonemal complex; trichogen cell; ovary; chorion; dorsal appendage. The phenotypic classes of alleles include: increased mortality during development; phenotype; visible; increased mortality; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, in stages of adults of both sexes.  "
FBgn0266489	CG45088	0.457152524	0.264135741	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG45088 (FBgn0266489). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:13580586..13593339. It has the cytological map location 50B3-50B4. Its molecular function is described by: . It is involved in the biological process described with: . One allele is reported. No phenotypic data is available. No phenotypic class data is available.
FBgn0037345	rev7	0.457574584	0.264097654	0.999936032	NA	MAD2L2	high	NA	NA	NA	"The gene rev7 is referred to in FlyBase by the symbol Dmel\rev7 (CG2948, FBgn0037345). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:5588873..5589703. It has the cytological map location 83B4. Protein features are: HORMA domain. Its molecular function is unknown. It is involved in the biological process described with: positive regulation of lyase activity; regulation of cell cycle. 5 alleles are reported. The phenotypes of these alleles manifest in: chaeta; mesothoracic tergum. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, in stages of adults of both sexes.  "
FBgn0264982	CR44133	0.457911128	0.27300988	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44133 (FBgn0264982). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3R:15986181..15993665. It has the cytological map location 89A11. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0050424	CG30424	0.458615995	0.235988101	0.999936032	NA	MB21D1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG30424 (FBgn0050424). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 2R:24965275..24967298. It has the cytological map location 60E11. Protein features are: Mab-21 domain. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed during late larval stages, during early pupal stages, in adult male stages.  "
FBgn0033271	CG8708	0.460616362	0.153259858	0.999936032	NA	C1GALT1;C1GALT1C1	moderate;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8708 (FBgn0033271). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2R:8159406..8161565. It has the cytological map location 44B5-44B7. Protein features are: C1GALT1; Fringe-like; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: beta-1,3-galactosyltransferase activity; glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity. It is involved in the biological process described with: O-glycan processing, core 1; protein glycosylation. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile; lethal; locomotor behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed in adult male stages.  "
FBgn0263831	Gen	0.460651442	0.23732969	0.999936032	NA	GEN1	high	NA	NA	NA	"The gene XPG-like endonuclease is referred to in FlyBase by the symbol Dmel\Gen (CG10670, FBgn0263831). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:5149849..5152376. It has the cytological map location 64C7. Protein features are: 5'-3' exonuclease, C-terminal domain; Helix-hairpin-helix motif, class 2; PIN domain-like; XPG N-terminal; XPG-I domain; XPG/Rad2 endonuclease. Its molecular function is described by: four-way junction DNA binding; endodeoxyribonuclease activity; 5'-3' exodeoxyribonuclease activity; single-stranded DNA 3'-5' exodeoxyribonuclease activity; endonuclease activity; crossover junction endodeoxyribonuclease activity; double-stranded DNA 3'-5' exodeoxyribonuclease activity; 5'-flap endonuclease activity. It is involved in the biological process described with: DNA catabolic process, endonucleolytic; DNA repair; double-strand break repair; DNA catabolic process, exonucleolytic. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during pupal stage; chemical sensitive; partially lethal - majority die; viable."
FBgn0265499	CR44368	0.460876839	0.260713462	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44368 (FBgn0265499). It is a non_protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts. Gene sequence location is 2R:14168844..14170917. It has the cytological map location 50E1. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0027932	Akap200	0.460961452	0.200836135	0.999936032	NA	NA	NA	NA	NA	NA	"The gene A kinase anchor protein 200 is referred to in FlyBase by the symbol Dmel\Akap200 (CG13388, FBgn0027932). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (3 unique). Gene sequence location is 2L:8415690..8431297. It has the cytological map location 29C3-29C4. Its molecular function is described by: protein kinase A binding. It is involved in the biological process described with: behavioral response to ethanol; negative regulation of Ras protein signal transduction; salivary gland cell autophagic cell death; regulation of establishment of planar polarity; autophagic cell death. 42 alleles are reported. The phenotypes of these alleles manifest in: antenna; wing; wing vein; outer nurse cell ring canal rim; inner nurse cell ring canal rim. The phenotypic classes of alleles include: fertile; increased mortality; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0027500	spd-2	0.46147376	0.169971977	0.999936032	NA	CEP192	high	NA	NA	NA	"The gene spindle defective 2 is referred to in FlyBase by the symbol Dmel\spd-2 (CG17286, FBgn0027500). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:16591207..16595014. It has the cytological map location 73A10-73A11. Protein features are: Immunoglobulin-like fold. Its molecular function is described by: adenosine-diphosphatase activity. It is involved in the biological process described with: astral microtubule organization; centrosome cycle; sperm aster formation. 8 alleles are reported. The phenotypes of these alleles manifest in: spermatocyte; spermatozoon; aster; spermatid; centriole; onion stage spermatid. The phenotypic classes of alleles include: sterile; increased mortality; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0264907	CG44098	0.461583398	0.269986267	0.999936032	NA	SLC22A2;SLC22A1	high;high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG44098 (FBgn0264907). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 3R:4750409..4773197. It has the cytological map location 82D4. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain; Major facilitator,  sugar transporter-like. Its molecular function is described by: organic anion transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable."
FBgn0051704	CG31704	0.461877037	0.198552482	0.999936032	NA	SPINK2	high	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG31704 (FBgn0051704). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:11840691..11841204. It has the cytological map location 33A3. Protein features are: Kazal domain. Its molecular function is unknown. It is involved in the biological process described with: multicellular organism reproduction. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during pupal stage; lethal - all die before end of pupal stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed in adult male stages.
FBgn0037515	Sp7	0.462097015	0.267438367	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene Serine protease 7 is referred to in FlyBase by the symbol Dmel\Sp7 (CG3066, FBgn0037515). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:7759786..7763947. It has the cytological map location 84D14-84E1. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Proteinase, regulatory CLIP domain; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: positive regulation of melanization defense response; melanization defense response; proteolysis. 19 alleles are reported. The phenotypes of these alleles manifest in: melanotic mass; embryonic/larval hemolymph. The phenotypic classes of alleles include: phenotype; increased mortality during development; increased mortality; lethal; wound healing defective; immune response defective; lethal - all die before end of P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0261797	Dhc64C	0.462571364	0.247774895	0.999936032	NA	DYNC1H1;DNAH12;DNAH8;DNAH3;DNAH1;DNAH7;DNAH6;DNAH11;DNAH10;DNAH17;DNAH2;DYNC2H1;DNAH5;DNAH9	high;low;low;low;low;low;low;low;low;low;low;low;low;low	NA	NA	NA	"The gene Dynein heavy chain 64C is referred to in FlyBase by the symbol Dmel\Dhc64C (CG7507, FBgn0261797). It is a protein_coding_gene from Drosophila melanogaster. It has 8 annotated transcripts and 8 polypeptides (all unique). Gene sequence location is 3L:4807368..4825687. It has the cytological map location 64B17-64C1. Protein features are: AAA+ ATPase domain; ATPase, dynein-related, AAA domain; Dynein heavy chain; Dynein heavy chain domain; Dynein heavy chain, AAA module D4; Dynein heavy chain, ATP-binding dynein motor region D5; Dynein heavy chain, coiled coil stalk; Dynein heavy chain, domain-1; Dynein heavy chain, domain-2; Dynein heavy chain, hydrolytic ATP-binding dynein motor region D1; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: ATP binding; dynein intermediate chain binding; microtubule motor activity; ATPase activity, coupled; dynein light chain binding; ATP-dependent microtubule motor activity, minus-end-directed; dynein light intermediate chain binding. It is involved in the biological process described with 40 unique terms, many of which group under: cellular macromolecule localization; positive regulation of cellular component organization; single-organism metabolic process; maintenance of location; amide transport; protein localization to organelle; head development; chitin-based cuticle development; establishment of Golgi localization; establishment or maintenance of apical/basal cell polarity; establishment or maintenance of cell polarity. 59 alleles are reported. The phenotypes of these alleles manifest in: testis; female germline cell; nuclear chromosome part; adult head; single-organism cellular process; stem cell; adult cerebral ganglion; late extended germ band embryo; condensed nuclear chromosome; cellular process. The phenotypic classes of alleles include: some die during embryonic stage; sterile; neuroanatomy defective; phenotype; increased mortality; some die during P-stage."
FBgn0024352	Stip1	0.462577772	0.197419147	0.999936032	NA	STIP1	high	NA	NA	NA	"The gene Stress induced phosphoprotein 1 is referred to in FlyBase by the symbol Dmel\Stip1 (CG2720, FBgn0024352). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:295122..297449. It has the cytological map location 21B8. Protein features are: Heat shock chaperonin-binding; Tetratricopeptide repeat; Tetratricopeptide repeat 1; Tetratricopeptide repeat-containing domain; Tetratricopeptide-like helical domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 11 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: wild-type; lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0029765	CG16756	0.462902717	0.189842067	0.999936032	NA	LYZL1;LYZL2;LYZL6;LALBA;SPACA5B;SPACA3;LYZL4;SPACA5;LYZ	moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG16756 (FBgn0029765). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:5427517..5428217. It has the cytological map location 4F10. Protein features are: Glycoside hydrolase, family 22; Glycoside hydrolase, family 22, conserved site; Lysozyme-like domain. Its molecular function is described by: lysozyme activity. It is involved in the biological process described with: cell wall macromolecule catabolic process; defense response to Gram-negative bacterium; defense response to Gram-positive bacterium. 3 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum. The phenotypic classes of alleles include: visible; viable; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed in adults stages of both sexes.  "
FBgn0043002	Chrac-14	0.463450232	0.251141238	0.999936032	NA	POLE3	high	NA	NA	NA	"The gene Chromatin accessibility complex 14kD protein is referred to in FlyBase by the symbol Dmel\Chrac-14 (CG13399, FBgn0043002). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:8437405..8437996. It has the cytological map location 29C4. Protein features are: Histone-fold; Transcription factor CBF/NF-Y/archaeal histone domain. Its molecular function is described by: protein heterodimerization activity; histone acetyltransferase activity; protein binding; nucleosome-dependent ATPase activity. It is involved in the biological process described with: cellular response to gamma radiation; nucleosome mobilization; histone acetylation; cellular response to DNA damage stimulus; CENP-A containing nucleosome assembly; chromatin remodeling. 5 alleles are reported. The phenotypes of these alleles manifest in: wing; chromosome. The phenotypic classes of alleles include: fertile; stress response defective; mitotic cell cycle defective; phenotype; flight defective; viable; eclosion defective; DNA repair defective; size defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0036842	CG3797	0.463503784	0.24343509	0.999936032	NA	UGT1A3;UGT2B10;UGT3A1;UGT8;UGT3A2;UGT1A1;UGT2B4;UGT2B15;UGT2B28;UGT2A2;UGT2B17;UGT2B11;UGT2A3;UGT2B7	moderate;moderate;moderate;moderate;moderate;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3797 (FBgn0036842). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:19059400..19062816. It has the cytological map location 75F6. Protein features are: UDP-glucuronosyl/UDP-glucosyltransferase. Its molecular function is described by: glucuronosyltransferase activity. It is involved in the biological process described with: metabolic process. 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0034271	Vps50	0.463729061	0.258800891	0.999936032	NA	VPS50	high	NA	NA	NA	"The gene Vacuolar protein sorting 50 is referred to in FlyBase by the symbol Dmel\Vps50 (CG4996, FBgn0034271). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:17739901..17743969. It has the cytological map location 54E5-54E7. Protein features are: Protein of unknown function DUF2451, C-terminal; Vacuolar protein sorting-associated protein 54, N-terminal. Its molecular function is described by: . It is involved in the biological process described with: endocytic recycling. 45 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0267514	5.8SrRNA-Psi:CR45854	0.463938196	0.229673806	0.999936032	NA	NA	NA	NA	NA	NA	"The gene 5.8S ribosomal RNA pseudogene:CR45854 is referred to in FlyBase by the symbol Dmel\5.8SrRNA-‘Â:CR45854 (CR45854, FBgn0267514). It is a pseudogene_attribute from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is X:23205258..23205380. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported."
FBgn0030499	CG11178	0.464196517	0.217030153	0.999936032	AVL9	AVL9	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11178 (FBgn0030499). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:13605681..13609529. It has the cytological map location 12A8. Protein features are: AVL9/DENND6 domain. Its molecular function is described by: . It is involved in the biological process described with: localization; cell migration. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0036493	CG7255	0.46426595	0.234539937	0.999936032	SLC7A2	SLC7A2;SLC7A3;SLC7A1;SLC7A4	moderate;moderate;moderate;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7255 (FBgn0036493). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (2 unique). Gene sequence location is 3L:15304255..15311195. It has the cytological map location 71C2. Protein features are: Amino acid/polyamine transporter I; Cationic amino acid transporter, C-terminal. Its molecular function is described by: amino acid transmembrane transporter activity. It is involved in the biological process described with: amino acid transmembrane transport. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 06-12 hour embryonic stages, during late larval stages.  "
FBgn0039296	CG10420	0.465271952	0.243210248	0.999936032	SIL1	SIL1;HSPBP1	high;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10420 (FBgn0039296). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:25233636..25235529. It has the cytological map location 96C7. Protein features are: Armadillo-like helical; Armadillo-type fold. Its molecular function is described by: . It is involved in the biological process described with: SRP-dependent cotranslational protein targeting to membrane, translocation. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die during embryonic stage; viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0000535	eag	0.465611981	0.21667458	0.999936032	NA	KCNH5;KCNH1	high;moderate	NA	transmembrane protein	NA	"The gene ether a go-go is referred to in FlyBase by the symbol Dmel\eag (CG10952, FBgn0000535). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (all unique). Gene sequence location is X:14955477..15009989. It has the cytological map location 13A1-13A5. Protein features are: Cyclic nucleotide-binding domain; Cyclic nucleotide-binding-like; Ion transport domain; PAC motif; PAS domain; PAS-associated, C-terminal; Potassium channel, voltage-dependent, EAG; Potassium channel, voltage-dependent, EAG/ELK/ERG; RmlC-like jelly roll fold. Its molecular function is described by: voltage-gated potassium channel activity; voltage-gated cation channel activity; phosphorelay sensor kinase activity. It is involved in the biological process described with 13 unique terms, many of which group under: establishment of localization; biological regulation; transport; protein oligomerization; potassium ion transport; regulation of heart contraction; system process; sensory perception of smell; courtship behavior; response to chemical; cellular developmental process. 25 alleles are reported. The phenotypes of these alleles manifest in: adult brain; synapse; neuromuscular junction; M band; leg; myofibril; sarcomere. The phenotypic classes of alleles include: flight defective; phenotype; behavior defective; sensory perception defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0035265	PIG-Wb	0.465827412	0.185796411	0.999936032	NA	PIGW	moderate	NA	transmembrane protein	NA	"The gene Phosphatidylinositol glycan anchor biosynthesis class W b is referred to in FlyBase by the symbol Dmel\PIG-Wb (CG18173, FBgn0035265). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:1735853..1738106. It has the cytological map location 62B1. Protein features are: GWT1. Its molecular function is described by: transferase activity, transferring acyl groups. It is involved in the biological process described with: GPI anchor biosynthetic process. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.  "
FBgn0033366	Ance-4	0.467483906	0.259158218	0.999936032	NA	ACE;TMEM27;ACE2	moderate;moderate;low	NA	NA	NA	"The gene Ance-4 is referred to in FlyBase by the symbol Dmel\Ance-4 (CG8196, FBgn0033366). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:9039728..9042142. It has the cytological map location 45A1. Protein features are: Peptidase M2, peptidyl-dipeptidase A. Its molecular function is described by: peptidyl-dipeptidase activity. It is involved in the biological process described with: proteolysis. 5 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the pupal period.  "
FBgn0039003	wfs1	0.468424608	0.248003572	0.999936032	WFS1	WFS1	high	NA	transmembrane protein	NA	"The gene wolfram syndrome 1 is referred to in FlyBase by the symbol Dmel\wfs1 (CG4917, FBgn0039003). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:22687542..22690380. It has the cytological map location 94C1. Protein features are: Wolframin family. Its molecular function is unknown. The biological processes in which it is involved are not known. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0260720	CR42547	0.46854598	0.264883105	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CR42547 (FBgn0260720). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2R:21631421..21634040. It has the cytological map location 57F5. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed within 00-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0005696	DNApol-alpha73	0.46938083	0.223344178	0.999936032	POLA2	POLA2	high	NA	NA	NA	"The gene DNA polymerase ‘± 73kD is referred to in FlyBase by the symbol Dmel\DNApol-‘±73 (CG5923, FBgn0005696). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:27239163..27241228. It has the cytological map location 97E10. Protein features are: DNA polymerase alpha, subunit B; DNA polymerase alpha, subunit B N-terminal; DNA polymerase alpha/epsilon, subunit B. Its molecular function is described by: protein heterodimerization activity; DNA-directed DNA polymerase activity; DNA binding. It is involved in the biological process described with: DNA-dependent DNA replication; DNA replication initiation. 3 alleles are reported. The phenotype of these alleles manifest in: eye. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0032251	Nse4	0.469476083	0.258276815	0.999936032	NA	NSMCE4A;EID3	high;moderate	NA	NA	NA	"The gene Non-SMC element 4 is referred to in FlyBase by the symbol Dmel\Nse4 (CG13142, FBgn0032251). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:10439440..10441047. It has the cytological map location 31E2. Protein features are: Non-structural maintenance of chromosome element 4, C-terminal; Nse4/EID family. Its molecular function is described by: SUMO transferase activity. It is involved in the biological process described with: DNA repair. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0082831	pps	0.469906513	0.262539196	0.999936032	NA	DIDO1;SPOCD1;PHF3	high;moderate;moderate	DNA-binding with transcription factor activity	NA	NA	"The gene protein partner of snf is referred to in FlyBase by the symbol Dmel\pps (CG6525, FBgn0082831). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:12413828..12421251. It has the cytological map location 87B9. Protein features are: BRK domain; Spen paralogue and orthologue SPOC, C-terminal; Transcription elongation factor S-II, central domain; Zinc finger, FYVE/PHD-type; Zinc finger, PHD-finger; Zinc finger, PHD-type; Zinc finger, PHD-type, conserved site; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: protein binding; hydrolase activity, acting on acid anhydrides. It is involved in the biological process described with: regulation of alternative mRNA splicing, via spliceosome; transcription, DNA-templated. 6 alleles are reported. The phenotype of these alleles manifest in: ovary. The phenotypic class of alleles includes: female sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, during early pupal stages, in adult female stages.  "
FBgn0037766	Teh1	0.469963356	0.163501554	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene tipE homolog 1 is referred to in FlyBase by the symbol Dmel\Teh1 (CG12806, FBgn0037766). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:9826081..9868120. It has the cytological map location 85E10-85E13. Protein features are: Na+ channel auxiliary subunit TipE. Its molecular function is described by: sodium channel regulator activity. It is involved in the biological process described with: regulation of sodium ion transport. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0036290	CG10638	0.470087636	0.21270525	0.999936032	NA	AKR1B10;AKR1A1;AKR1D1;AKR1B15;AKR1E2;AKR1B1;AKR1C2;AKR1C1;AKR1C3;AKR1C4	moderate;moderate;moderate;low;low;low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10638 (FBgn0036290). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:12498106..12501311. It has the cytological map location 69C3-69C4. Protein features are: Aldo/keto reductase; Aldo/keto reductase, conserved site; NADP-dependent oxidoreductase domain. Its molecular function is described by: oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. 14 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in adult female stages.  "
FBgn0263235	Phae2	0.471872354	0.174955825	0.999936032	NA	PRSS36;PRSS53;PRSS57;PRSS33	low;low;low;low	NA	NA	NA	"The gene Phaedra 2 is referred to in FlyBase by the symbol Dmel\Phae2 (CG16997, FBgn0263235). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:12111110..12112256. It has the cytological map location 33C4. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 8 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable."
FBgn0035603	Pfdn4	0.472348332	0.22244362	0.999936032	NA	PFDN4	high	NA	NA	NA	"The gene Prefoldin 4 is referred to in FlyBase by the symbol Dmel\Pfdn4 (CG10635, FBgn0035603). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:5367341..5368008. It has the cytological map location 64C13-64C14. Protein features are: Prefoldin beta-like; Prefoldin, subunit 4. Its molecular function is described by: chaperone binding; unfolded protein binding. It is involved in the biological process described with: protein folding. 4 alleles are reported. The phenotypes of these alleles manifest in: type II neuroblast; type I neuroblast; mesothoracic tergum. The phenotypic classes of alleles include: flight defective; viable; body color defective; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0051155	Rpb7	0.472637751	0.220761537	0.999936032	NA	POLR2G	high	Maybe TF	NA	NA	"The gene Rpb7 is referred to in FlyBase by the symbol Dmel\Rpb7 (CG31155, FBgn0051155). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:15222251..15223180. It has the cytological map location 88E3. Protein features are: Nucleic acid-binding, OB-fold; RNA polymerase Rpb7, N-terminal; S1 domain. Its molecular function is described by: nucleic acid binding; protein binding; DNA-directed 5'-3' RNA polymerase activity. It is involved in the biological process described with: transcription from RNA polymerase II promoter. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; lethal; lethal - all die during P-stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0032068	LManV	0.473269921	0.173883634	0.999936032	NA	MAN2B1;MAN2B2	moderate;low	NA	NA	NA	"The gene Lysosomal ‘±-mannosidase V is referred to in FlyBase by the symbol Dmel\LManV (CG9466, FBgn0032068). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:8772946..8776263. It has the cytological map location 29F1. Protein features are: Galactose mutarotase-like domain; Glycoside hydrolase 38/57, N-terminal domain; Glycoside hydrolase families 57/38, central domain; Glycoside hydrolase family 38, N-terminal domain; Glycoside hydrolase family 38, central domain; Glycoside hydrolase/deacetylase, beta/alpha-barrel; Glycosyl hydrolase family 38, C-terminal. Its molecular function is described by: alpha-mannosidase activity; carbohydrate binding. It is involved in the biological process described with: mannose metabolic process; protein deglycosylation. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the larval period, in adult male stages.  "
FBgn0262741	MRE23	0.473272157	0.258945942	0.999936032	NA	NA	NA	NA	NA	NA	"The gene mRNA-like ncRNA in embryogenesis 23 is referred to in FlyBase by the symbol Dmel\MRE23 (CR43126, FBgn0262741). It is a non_protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts. Gene sequence location is 3R:28586048..28591386. It has the cytological map location 98D5. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported."
FBgn0010607	l(2)05714	0.473827244	0.231874998	0.999936032	NA	NA	NA	NA	NA	NA	"The gene lethal (2) 05714 is referred to in FlyBase by the symbol Dmel\l(2)05714 (CG8886, FBgn0010607). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:4970135..4973921. It has the cytological map location 25B5. Its molecular function is described by: . It is involved in the biological process described with: . 5 alleles are reported. The phenotypes of these alleles manifest in: myofibril; sarcomere; mesothoracic tergum; indirect flight muscle. The phenotypic classes of alleles include: viable; visible; flightless; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0042712	HBS1	0.476559285	0.204131213	0.999936032	NA	HBS1L	high	NA	NA	NA	"The gene HBS1 is referred to in FlyBase by the symbol Dmel\HBS1 (CG1898, FBgn0042712). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:1862881..1865240. It has the cytological map location 62B7. Protein features are: HBS1-like protein, N-terminal; P-loop containing nucleoside triphosphate hydrolase; Transcription factor, GTP-binding domain; Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal; Translation elongation factor EFTu-like, domain 2; Translation elongation factor EFTu/EF1A, C-terminal; Translation protein, beta-barrel domain. Its molecular function is described by: GTPase activity; protein binding; GTP binding. It is involved in the biological process described with: positive regulation of innate immune response; translation; defense response to Gram-negative bacterium; posttranscriptional gene silencing. 5 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: some die during pupal stage; partially lethal - majority die; visible; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0259789	zld	0.476951162	0.183976567	0.999936032	NA	ZNF114	low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene zelda is referred to in FlyBase by the symbol Dmel\zld (CG12701, FBgn0259789). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is X:19766465..19783548. It has the cytological map location 18F. Protein features are: Armadillo-like helical; WD40/YVTN repeat-like-containing domain; Zinc finger C2H2-type; Zinc finger, RING/FYVE/PHD-type; Zinc finger, double-stranded RNA binding. Its molecular function is described by: sequence-specific DNA binding; protein binding; transcription regulatory region sequence-specific DNA binding. It is involved in the biological process described with: mitotic cell cycle; regulation of imaginal disc-derived wing size; positive regulation of transcription, DNA-templated; cellularization. 19 alleles are reported. The phenotypes of these alleles manifest in: developing embryonic structure; presumptive embryonic/larval system; cell projection; embryonic/larval neuron; membrane-bounded organelle; hemocyte; cell component; sensory organ cell; larva; axon; blastoderm embryo; nucleus; embryonic/larval circulatory system. The phenotypic classes of alleles include: increased mortality; increased mortality during development; phenotype; lethal - all die before end of embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0004389	bnk	0.47700596	0.25586797	0.999936032	NA	NA	NA	NA	NA	NA	"The gene bottleneck is referred to in FlyBase by the symbol Dmel\bnk (CG1480, FBgn0004389). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:31193362..31194389. It has the cytological map location 100B5. Its molecular function is described by: phosphatidylinositol-4,5-bisphosphate binding; actin binding; phosphatidylinositol-3,4,5-trisphosphate binding. It is involved in the biological process described with: actin filament bundle organization; actin filament organization; actomyosin contractile ring assembly; membrane organization; regulation of embryonic cell shape; cellularization. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: wild-type. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0260866	dnr1	0.477133282	0.188646003	0.999936032	NA	MYLIP	high	NA	NA	NA	"The gene defense repressor 1 is referred to in FlyBase by the symbol Dmel\dnr1 (CG12489, FBgn0260866). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:22563152..22592964. It has the cytological map location 58E9-58F1. Protein features are: Band 4.1 domain; FERM central domain; FERM domain; FERM, C-terminal PH-like domain; FERM, N-terminal; FERM/acyl-CoA-binding protein, 3-helical bundle; PH domain-like; Ubiquitin-related domain; Zinc finger, RING-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: zinc ion binding; ubiquitin-protein transferase activity. It is involved in the biological process described with: sleep; negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria; protein ubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process. 24 alleles are reported. The phenotype of these alleles manifest in: adult brain. The phenotypic classes of alleles include: neuroanatomy defective; gravitaxis defective; short lived; viable; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 06-24 hour embryonic stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0002526	LanA	0.47727235	0.242486921	0.999936032	NA	LAMA5;LAMA3;LAMA4;LAMA2;LAMC1;LAMA1	high;high;moderate;low;low;low	NA	NA	NA	"The gene Laminin A is referred to in FlyBase by the symbol Dmel\LanA (CG10236, FBgn0002526). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:6203831..6218022. It has the cytological map location 65A8-65A9. Protein features are: Concanavalin A-like lectin/glucanase domain; EGF-like domain; EGF-like, conserved site; Galactose-binding domain-like; Laminin EGF domain; Laminin G domain; Laminin IV; Laminin alpha, domain I; Laminin domain II; Laminin, N-terminal; Tyrosine-protein kinase ephrin type A/B receptor-like. Its molecular function is described by: receptor binding. It is involved in the biological process described with 14 unique terms, many of which group under: cell adhesion; multi-organism behavior; immune response; synapse organization; open tracheal system development; single organism cell adhesion; meiotic chromosome segregation; regulation of cell adhesion; generation of neurons; reproduction; aggressive behavior; organic hydroxy compound metabolic process; tissue development; synaptic growth at neuromuscular junction. 29 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval circulatory system; reproductive system; neuromuscular junction; optic nerve; extracellular region part; abdominal 5 ventral acute muscle 3; abdominal 7 acute muscle; imaginal disc; cell component; glial cell. The phenotypic classes of alleles include: immune response defective; increased mortality; cell cycle defective; lethal - all die before end of first instar larval stage; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 06-24 hour embryonic stages.  "
FBgn0044030	mRpS14	0.477764795	0.193549261	0.999936032	NA	MRPS14	high	NA	NA	NA	"The gene mitochondrial ribosomal protein S14 is referred to in FlyBase by the symbol Dmel\mRpS14 (CG32531, FBgn0044030). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:19479382..19480238. It has the cytological map location 18C7. Protein features are: Ribosomal protein S14. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation. One allele is reported. The phenotype of this allele manifest in: trichogen cell. The phenotypic classes of allele include: pain response defective; viable; visible; lethal - all die during larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed during early larval stages.  "
FBgn0035300	CG1139	0.478464404	0.183107605	0.999936032	NA	SLC36A3;SLC36A2;SLC36A1;SLC36A4	moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1139 (FBgn0035300). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:1971638..1974285. It has the cytological map location 62B12. Protein features are: Amino acid transporter, transmembrane domain. Its molecular function is described by: amino acid transmembrane transporter activity. It is involved in the biological process described with: amino acid transmembrane transport; growth. 5 alleles are reported. The phenotypes of these alleles manifest in: ommatidium; wing; eye. The phenotypic classes of alleles include: decreased cell number; viable; increased cell size; increased cell number. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during late larval stages.  "
FBgn0261393	alpha-Est5	0.478571998	0.181162164	0.999936032	NA	CES4A;CES2;NLGN2;CES5A;CES1;CEL;NLGN4X;NLGN1;NLGN3;NLGN4Y;CES3	low;low;low;low;low;low;low;low;low;low;low	NA	NA	NA	"The gene ‘±-Esterase-5 is referred to in FlyBase by the symbol Dmel\‘±-Est5 (CG1089, FBgn0261393). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:7533496..7536390. It has the cytological map location 84D4-84D5. Protein features are: Alpha/Beta hydrolase fold; Carboxylesterase, type B. Its molecular function is described by: carboxylic ester hydrolase activity. The biological processes in which it is involved are not known. 22 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: electrophoretic variant; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the larval period.  "
FBgn0051249	CG31249	0.479757566	0.237884616	0.999936032	NA	C14orf166	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31249 (FBgn0051249). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:17685689..17687071. It has the cytological map location 90C1. Protein features are: Protein of unknown function UPF0568. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: body color defective; fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, during early pupal stages, in adult female stages.  "
FBgn0025680	cry	0.480314883	0.182282567	0.999936032	NA	CRY2;CRY1	moderate;low	NA	transmembrane protein	GPCR	"The gene cryptochrome is referred to in FlyBase by the symbol Dmel\cry (CG3772, FBgn0025680). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:19212154..19215442. It has the cytological map location 91F11. Protein features are: Cryptochrome/DNA photolyase class 1; Cryptochrome/DNA photolyase, FAD-binding domain; DNA photolyase, N-terminal; Rossmann-like alpha/beta/alpha sandwich fold. Its molecular function is described by: photoreceptor activity; G-protein coupled photoreceptor activity; FAD binding; blue light photoreceptor activity; flavin adenine dinucleotide binding; protein binding. It is involved in the biological process described with 20 unique terms, many of which group under: response to abiotic stimulus; rhythmic behavior; response to blue light; circadian rhythm; single-organism behavior; protein targeting to nucleus; response to magnetism; phototransduction; cellular response to light stimulus; cellular response to radiation. 38 alleles are reported. The phenotypes of these alleles manifest in: cytoplasmic part; intracellular; supramolecular fiber; organelle; adult pacemaker neuron; sense organ; head segment; embryo; contractile fiber; scutellum; late embryo. The phenotypic classes of alleles include: behavior defective; increased mortality during development; phenotype; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed in adult male stages.  "
FBgn0033467	CG15863	0.480875033	0.250384	0.999936032	NA	PDRG1	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG15863 (FBgn0033467). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:9959119..9959732. It has the cytological map location 46C7. Protein features are: p53 and DNA damage-regulated protein 1. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0051176	CG31176	0.481229143	0.21530673	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG31176 (FBgn0051176). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:21672303..21719660. It has the cytological map location 93F2-93F6. Its molecular function is unknown. The biological processes in which it is involved are not known. 19 alleles are reported. The phenotypes of these alleles manifest in: germline cell; intersegmental nerve. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages.
FBgn0004395	unk	0.481292475	0.228314547	0.999936032	NA	UNK;UNKL	high;moderate	NA	NA	NA	"The gene unkempt is referred to in FlyBase by the symbol Dmel\unk (CG4620, FBgn0004395). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (4 unique). Gene sequence location is 3R:23149653..23157862. It has the cytological map location 94E1-94E2. Protein features are: Zinc finger, CCCH-type; Zinc finger, RING-type. Its molecular function is described by: zinc ion binding; DNA binding; metal ion binding. It is involved in the biological process described with: chaeta morphogenesis; imaginal disc-derived wing morphogenesis; regulation of neurogenesis; neuron differentiation; larval development; compound eye development. 20 alleles are reported. The phenotypes of these alleles manifest in: rhabdomere; photoreceptor cell R6; wing; ommatidium; embryonic head; trichogen cell; photoreceptor cell R7; photoreceptor cell R1; scutellar bristle. The phenotypic classes of alleles include: lethal; increased mortality; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis.  "
FBgn0027660	blot	0.481373224	0.251083524	0.999936032	NA	SLC6A8	low	NA	transmembrane protein	NA	"The gene bloated tubules is referred to in FlyBase by the symbol Dmel\blot (CG3897, FBgn0027660). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is 3L:17396031..17421514. It has the cytological map location 74B1-74B2. Protein features are: Sodium:neurotransmitter symporter. Its molecular function is described by: transporter activity; neurotransmitter:sodium symporter activity. It is involved in the biological process described with: morphogenesis of an epithelium; neurotransmitter transport; transport. 16 alleles are reported. The phenotypes of these alleles manifest in: denticle; ovariole; embryo; pole cell; Malpighian tubule. The phenotypic classes of alleles include: fertile; increased mortality; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0036411	Sox21a	0.481703614	0.248302957	0.999936032	NA	SOX21;SOX14;SOX12;SOX4	moderate;low;low;low	DNA-binding with transcription factor activity(HMG_box)	NA	NA	"The gene Sox21a is referred to in FlyBase by the symbol Dmel\Sox21a (CG7345, FBgn0036411). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:14103481..14108118. It has the cytological map location 70D2. Protein features are: High mobility group box domain. Its molecular function is unknown. It is involved in the biological process described with: negative regulation of cell differentiation; stem cell proliferation; phagocytosis; enterocyte differentiation. 16 alleles are reported. The phenotypes of these alleles manifest in: adult anterior midgut epithelium; adult midgut; intestinal stem cell; trichogen cell; enterocyte; enteroendocrine cell; enteroblast; adult midgut epithelium. The phenotypic classes of alleles include: increased mortality during development; phenotype; increased mortality; cell number defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult male stages.  "
FBgn0262962	CG43273	0.482976733	0.240860089	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG43273 (FBgn0262962). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:24830301..24830973. It has the cytological map location 96A24. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported.
FBgn0015591	AstA	0.48334412	0.209984982	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Allatostatin A is referred to in FlyBase by the symbol Dmel\AstA (CG13633, FBgn0015591). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:24760530..24765071. It has the cytological map location 96A20. Protein features are: Allatostatin. Its molecular function is described by: hormone activity; receptor binding; neuropeptide receptor binding; neuropeptide hormone activity. It is involved in the biological process described with: neuropeptide signaling pathway; negative regulation of juvenile hormone biosynthetic process. 12 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; feeding behavior defective; long lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in adult male stages.  "
FBgn0033303	Cyp6a15Psi	0.486066355	0.108847334	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Cyp6a15‘Â is referred to in FlyBase by the symbol Dmel\Cyp6a15‘Â (CR14753, FBgn0033303). It is a pseudogene_attribute from Drosophila melanogaster. It has 2 annotated transcripts. Gene sequence location is 2R:8569137..8570306. It has the cytological map location 44D3. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed in adult male stages.  "
FBgn0030607	dob	0.486322089	0.151596231	0.999936032	NA	PNPLA2;PNPLA3;PNPLA5;PNPLA1;PNPLA4	moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"The gene doppelganger von brummer is referred to in FlyBase by the symbol Dmel\dob (CG5560, FBgn0030607). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:15067007..15069091. It has the cytological map location 13A8. Protein features are: Acyl transferase/acyl hydrolase/lysophospholipase; Patatin-like phospholipase domain; Patatin-like phospholipase domain-containing protein. Its molecular function is described by: triglyceride lipase activity. It is involved in the biological process described with: lipid homeostasis; triglyceride catabolic process. 3 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; embryonic/larval hemocyte. The phenotypic classes of alleles include: visible; viable; fertile; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0003499	sr	0.486416427	0.194429383	0.999936032	NA	EGR2;EGR1;EGR3;EGR4	high;moderate;moderate;moderate	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene stripe is referred to in FlyBase by the symbol Dmel\sr (CG7847, FBgn0003499). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 3R:18090803..18135583. It has the cytological map location 90E4-90F1. Protein features are: Tetratricopeptide-like helical domain; WD40/YVTN repeat-like-containing domain; Zinc finger C2H2-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: nucleic acid binding. It is involved in the biological process described with: determination of muscle attachment site; ectoderm development; central nervous system development; epithelial cell migration, open tracheal system; somatic muscle development; germ-band shortening; phagocytosis; muscle organ development; pigment metabolic process; regulation of glucose metabolic process. 63 alleles are reported. The phenotypes of these alleles manifest in: abdominal 7 ventral longitudinal muscle; cell cluster organ; mesoderm; adult integumentary system; skeletal muscle of thorax; endocuticular specialization; external sensillum; embryonic/larval ganglionic branch; adult abdomen; integumentary specialisation; abdominal 6 lateral transverse muscle; external sensory organ. The phenotypic classes of alleles include: lethal - all die before end of P-stage; increased mortality during development; phenotype; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-18 embryonic stages.  "
FBgn0000247	ca	0.486971019	0.226465153	0.999936032	NA	SERGEF;RCBTB1;RCBTB2	moderate;high;high	NA	NA	NA	"The gene claret is referred to in FlyBase by the symbol Dmel\ca (CG31037, FBgn0000247). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:29806811..29815047. It has the cytological map location 99C2. Protein features are: Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; Regulator of chromosome condensation, RCC1; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: Rab GTPase binding; Rab guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: eye pigment granule organization; negative regulation of gene silencing by RNA; eye pigment precursor transport; regulation of lipid storage; ommochrome biosynthetic process; regulation of Rab protein signal transduction; regulation of autophagy. 67 alleles are reported. The phenotypes of these alleles manifest in: ocellus; adult integumentary system; frons; ommatidium; male organism; male genitalia; Malpighian tubule; adult segment; adult abdomen; postfrons. The phenotypic classes of alleles include: eye color defective; visible; viable; male sterile; female sterile; wild-type. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0010288	Uch	0.488137799	0.175948382	0.999936032	UCHL3	UCHL3;UCHL1	high;moderate	NA	NA	NA	"The gene Ubiquitin carboxy-terminal hydrolase is referred to in FlyBase by the symbol Dmel\Uch (CG4265, FBgn0010288). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:2212738..2214211. It has the cytological map location 22D4. Protein features are: Peptidase C12, ubiquitin carboxyl-terminal hydrolase. Its molecular function is described by: thiol-dependent ubiquitin-specific protease activity. It is involved in the biological process described with: ubiquitin-dependent protein catabolic process; protein deubiquitination. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.  "
FBgn0259108	futsch	0.48817366	0.214066276	0.999936032	NA	MAP1A;MAP1B;MAP1S	high;high;moderate	NA	NA	NA	"The gene futsch is referred to in FlyBase by the symbol Dmel\futsch (CG34387, FBgn0259108). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is X:1409069..1453686. It has the cytological map location 2A2. Protein features are: Metallo-beta-lactamase; Microtubule associated protein 1; Microtubule associated protein Futsch. Its molecular function is described by: kinase binding; protein binding; microtubule binding. It is involved in the biological process described with 13 unique terms, many of which group under: associative learning; single-organism localization; dendrite development; regulation of nervous system development; single-organism behavior; regulation of growth; negative regulation of apoptotic process; movement of cell or subcellular component; cytoskeleton organization; microtubule-based process. 29 alleles are reported. The phenotypes of these alleles manifest in: cell part; synapse; embryo; photoreceptor cell; plasma membrane bounded cell projection; tract; neuromuscular junction; embryonic/larval neuromuscular junction; polymeric cytoskeletal fiber; ventral nerve cord. The phenotypic classes of alleles include: phenotype; smell perception defective; increased mortality; short lived; male fertile; sensory perception defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed during early larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0040299	Myo28B1	0.488421594	0.177277048	0.999936032	NA	MYO7B;MYO7A;MYO15A;MYO10	moderate;moderate;low;moderate	NA	NA	NA	"The gene Myosin 28B1 is referred to in FlyBase by the symbol Dmel\Myo28B1 (CG6976, FBgn0040299). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 2L:7666047..7689459. It has the cytological map location 28C1. Protein features are: Band 4.1 domain; FERM central domain; FERM domain; FERM, N-terminal; FERM/acyl-CoA-binding protein, 3-helical bundle; IQ motif, EF-hand binding site; MyTH4 domain; Myosin head, motor domain; P-loop containing nucleoside triphosphate hydrolase; PH domain-like; Ubiquitin-related domain. Its molecular function is described by: microfilament motor activity; actin-dependent ATPase activity; motor activity; actin binding; ATPase activity, coupled; ATP binding. It is involved in the biological process described with: actin filament-based movement. 12 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; male genitalia. The phenotypic classes of alleles include: visible; lethal - all die during P-stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages.  "
FBgn0034318	CG14500	0.490180859	0.171843669	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG14500 (FBgn0034318). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:18188978..18189654. It has the cytological map location 55B12. Protein features are: C-type lectin fold; C-type lectin-like; C-type lectin-like/link domain. Its molecular function is described by: carbohydrate binding. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period.
FBgn0034247	CG6484	0.490337328	0.160492411	0.999936032	NA	SLC2A8;SLC2A6	moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6484 (FBgn0034247). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:17582007..17584012. It has the cytological map location 54C10. Protein features are: Major facilitator superfamily domain; Major facilitator,  sugar transporter-like; Sugar transporter, conserved site; Sugar/inositol transporter. Its molecular function is described by: sugar:proton symporter activity; glucose transmembrane transporter activity. It is involved in the biological process described with: glucose import; hexose transmembrane transport. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, in stages of adults of both sexes.  "
FBgn0032136	Apoltp	0.490364958	0.194789167	0.999936032	NA	APOB;LOC400499	moderate;moderate	NA	NA	NA	"The gene Apolipoprotein lipid transfer particle is referred to in FlyBase by the symbol Dmel\Apoltp (CG15828, FBgn0032136). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:9634179..9656026. It has the cytological map location 30C2. Protein features are: Lipid transport protein, N-terminal; Lipid transport protein, beta-sheet shell; Lipid transport, open beta-sheet; Vitellinogen, beta-sheet N-terminal; Vitellinogen, open beta-sheet; Vitellinogen, open beta-sheet, subdomain 1; Vitellinogen, superhelical; von Willebrand factor, type D domain. Its molecular function is described by: lipid transporter activity; lipoprotein particle receptor binding. It is involved in the biological process described with: positive regulation of lipid transport; sterol transport; acylglycerol transport. 15 alleles are reported. The phenotypes of these alleles manifest in: egg chamber; wing disc; embryonic/larval midgut; embryonic/larval hemolymph; embryonic/larval fat body; embryonic/larval brain. The phenotypic classes of alleles include: lethal - all die during first instar larval stage; female semi-fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 06-24 hour embryonic stages, during early larval stages.  "
FBgn0260932	cuff	0.490460142	0.187040352	0.999936032	NA	DXO	moderate	NA	NA	NA	"The gene cutoff is referred to in FlyBase by the symbol Dmel\cuff (CG13190, FBgn0260932). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:11886067..11887603. It has the cytological map location 48C5. Protein features are: RAI1-like. Its molecular function is described by: . It is involved in the biological process described with: dorsal/ventral pattern formation; piRNA metabolic process; P granule organization; germarium-derived female germ-line cyst formation; ovarian fusome organization; oogenesis; production of siRNA involved in RNA interference; karyosome formation. 19 alleles are reported. The phenotype of these alleles manifest in: chorion. The phenotypic classes of alleles include: viable; female sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0015371	chn	0.491462892	0.213348042	0.999936032	NA	NA	NA	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene charlatan is referred to in FlyBase by the symbol Dmel\chn (CG11798, FBgn0015371). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (7 unique). Gene sequence location is 2R:15115236..15144783. It has the cytological map location 51E1-51E2. Protein features are: WD40/YVTN repeat-like-containing domain; Zinc finger C2H2-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding; protein binding; sequence-specific DNA binding. It is involved in the biological process described with 12 unique terms, many of which group under: anatomical structure development; phototransduction; generation of neurons; regulation of cell differentiation; peripheral nervous system development; embryonic development via the syncytial blastoderm; positive regulation of macromolecule biosynthetic process; cellular component morphogenesis; eye development; regulation of biological quality; larval somatic muscle development; single organism signaling. 41 alleles are reported. The phenotypes of these alleles manifest in: dendritic arborizing neuron; embryonic tagma; embryonic/larval thoracic/abdominal ventral sensory cluster; muscle cell; larva; immaterial anatomical entity; ventral abdominal cluster; adult external head; embryonic/larval ventral sensory cluster of A1-7; posterior notopleural bristle; posterior supraalar bristle. The phenotypic classes of alleles include: lethal; increased mortality; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0001987	Gli	0.492326088	0.181485599	0.999936032	NA	NLGN2;NLGN4X;NLGN1;NLGN3;NLGN4Y;CEL	moderate;low;low;low;low;moderate	NA	transmembrane protein	NA	"The gene Gliotactin is referred to in FlyBase by the symbol Dmel\Gli (CG3903, FBgn0001987). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is 2L:15756002..15762758. It has the cytological map location 35D4. Protein features are: Alpha/Beta hydrolase fold; Carboxylesterase type B, conserved site; Carboxylesterase, type B. Its molecular function is described by: carboxylic ester hydrolase activity; receptor activity; neurexin family protein binding. It is involved in the biological process described with 14 unique terms, many of which group under: biological regulation; biological adhesion; cell-cell junction organization; presynaptic membrane organization; vesicle-mediated transport; imaginal disc-derived wing morphogenesis; regulation of biological process; single organismal cell-cell adhesion; cell junction assembly; male gamete generation; neuron cell-cell adhesion; cell cycle; heart development; establishment of synaptic vesicle localization; imaginal disc morphogenesis. 59 alleles are reported. The phenotypes of these alleles manifest in: apical junction complex; adult thoracic sensillum; cell-cell junction; follicle cell; intracellular organelle; larval mesothoracic segment; extended germ band embryo; gland; adult sensillum; pleated septate junction; segmental nerve branch SNa of A1-7; intracellular; foregut; presumptive embryonic/larval system; embryonic/first instar larval cuticle; tormogen cell. The phenotypic classes of alleles include: lethal - all die before end of prepupal stage; increased mortality during development; phenotype; cell death defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0003328	scb	0.492596157	0.168963091	0.999936032	NA	ITGA4;ITGAL;ITGAE;ITGAM;ITGA2;ITGAD;ITGA11;ITGA10;ITGA1;ITGAX;ITGA9	high;moderate;moderate;moderate;moderate;moderate;moderate;moderate;low;moderate;low	NA	transmembrane protein	NA	"The gene scab is referred to in FlyBase by the symbol Dmel\scb (CG8095, FBgn0003328). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:15248784..15258498. It has the cytological map location 51E10-51E11. Protein features are: Integrin alpha beta-propellor; Integrin alpha chain; Integrin alpha chain, C-terminal cytoplasmic region, conserved site; Integrin alpha-2; Integrin domain. Its molecular function is described by: receptor activity; cell adhesion molecule binding; protein heterodimerization activity. It is involved in the biological process described with 26 unique terms, many of which group under: biological adhesion; cell adhesion; tissue morphogenesis; cognition; cell-substrate adhesion; single-organism transport; cell-cell adhesion; neurological system process; pericardium morphogenesis; multi-organism reproductive process; exocrine system development; response to oxygen-containing compound; negative regulation of multicellular organismal process; regulation of localization; neuron projection development. 41 alleles are reported. The phenotypes of these alleles manifest in: synapse; fascicle; embryonic dorsal epidermis; gland; pericardial cell; cell leading edge; peripheral nervous system; stage 7 embryo; polymeric cytoskeletal fiber; hemocoel. The phenotypic classes of alleles include: phenotype; viable; increased mortality during development; memory defective; lethal - all die before end of pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed during early pupal stages.  "
FBgn0003943	Ubi-p63E	0.492614145	0.169172904	0.999936032	UBC	UBC;UBB;UBD;ISG15	high;moderate;moderate;moderate	NA	NA	NA	"The gene Ubiquitin-63E is referred to in FlyBase by the symbol Dmel\Ubi-p63E (CG11624, FBgn0003943). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 3L:3899259..3903184. It has the cytological map location 63F5. Protein features are: Ubiquitin; Ubiquitin conserved site; Ubiquitin domain; Ubiquitin-related domain. Its molecular function is described by: protein tag. It is involved in the biological process described with: phagocytosis; larval midgut cell programmed cell death; protein ubiquitination; autophagy. 14 alleles are reported. The phenotypes of these alleles manifest in: testis; spermatocyte. The phenotypic classes of alleles include: fertile; meiotic cell cycle defective; viable; male sterile; female fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 06-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0053469	CG33469	0.494332201	0.235681474	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG33469 (FBgn0053469). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:14605652..14606302. It has the cytological map location 51B6. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages.
FBgn0000592	Est-6	0.495043773	0.238806639	0.999936032	NA	CES4A;CES2;NLGN2;CES5A;CES1;CEL;NLGN4X;NLGN1;NLGN3;NLGN4Y;CES3	low;low;low;low;low;low;low;low;low;low;low	NA	NA	NA	"The gene Esterase 6 is referred to in FlyBase by the symbol Dmel\Est-6 (CG6917, FBgn0000592). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:12188818..12190705. It has the cytological map location 69A1. Protein features are: Alpha/Beta hydrolase fold; Carboxylesterase type B, active site; Carboxylesterase type B, conserved site; Carboxylesterase, type B. Its molecular function is described by: carboxylic ester hydrolase activity; short-chain carboxylesterase activity. It is involved in the biological process described with: ovulation; courtship behavior; sperm storage; multicellular organism reproduction; regulation of female receptivity, post-mating; regulation of oviposition; organic substance catabolic process; pheromone biosynthetic process; mating. 86 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; partially lethal - majority die; electrophoretic variant; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed in adult male stages.  "
FBgn0261631	CG42714	0.495151505	0.170319981	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG42714 (FBgn0261631). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:6233491..6234056. It has the cytological map location 65A10. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, in adult male stages.  "
FBgn0034736	gas	0.495606631	0.166448344	0.999936032	NA	CES4A	high	NA	NA	NA	"The gene gasoline is referred to in FlyBase by the symbol Dmel\gas (CG6018, FBgn0034736). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:22550094..22552113. It has the cytological map location 58E8. Protein features are: Alpha/Beta hydrolase fold; Carboxylesterase, type B. Its molecular function is unknown. It is involved in the biological process described with: detection of temperature stimulus involved in sensory perception of pain. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: heat stress response defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0013672	mt:ATPase6	0.495794379	0.155961782	0.999936032	NA	ATP6;ATP8	high;moderate	NA	transmembrane protein	NA	"The gene mitochondrial ATPase subunit 6 is referred to in FlyBase by the symbol Dmel\mt:ATPase6 (CG34073, FBgn0013672). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is mitochondrion_genome:4062..4736. Protein features are: ATP synthase, F0 complex, subunit A; ATP synthase, F0 complex, subunit A, active site. Its molecular function is described by: proton-transporting ATP synthase activity, rotational mechanism; hydrogen-exporting ATPase activity, phosphorylative mechanism. It is involved in the biological process described with: mitochondrial ATP synthesis coupled proton transport; muscle cell cellular homeostasis; neuron cellular homeostasis; determination of adult lifespan; locomotion; ATP synthesis coupled proton transport; proton transport. 3 alleles are reported. The phenotypes of these alleles manifest in: adult somatic muscle; thoracico-abdominal ganglion; mitochondrial inner membrane; flight muscle; mitochondrial crista. The phenotypic classes of alleles include: behavior defective; neuroanatomy defective; neurophysiology defective; phenotype; stress response defective; paralytic; increased mortality; short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult male stages.  "
FBgn0039969	Fis1	0.496129444	0.162323424	0.999936032	NA	FIS1	high	NA	transmembrane protein	NA	"The gene Fission, mitochondrial 1 is referred to in FlyBase by the symbol Dmel\Fis1 (CG17510, FBgn0039969). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (4 unique). Gene sequence location is 2R:5603587..5604834. It has the cytological map location 41F5. Protein features are: Fis1, C-terminal tetratricopeptide repeat; Fis1, N-terminal tetratricopeptide repeat; Mitochondria fission 1 protein; Mitochondria fission protein Fis1, cytosolic domain; Tetratricopeptide-like helical domain. Its molecular function is unknown. It is involved in the biological process described with: mitochondrion organization; positive regulation of mitochondrial fission. 4 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval motor neuron; mitochondrion. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed during late larval stages.  "
FBgn0050361	mtt	0.496782852	0.224839394	0.999936032	NA	GRM8;GRM1;GRM7;GRM4;GRM5;GRM6;GRM3;GRM2	high;high;moderate;moderate;moderate;moderate;low;low	NA	transmembrane protein	GPCR	"The gene mangetout is referred to in FlyBase by the symbol Dmel\mtt (CG30361, FBgn0050361). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (all unique). Gene sequence location is 2R:8473956..8532294. It has the cytological map location 44D1-44D2. Protein features are: GPCR family 3, C-terminal; GPCR, family 3; GPCR, family 3, conserved site; GPCR, family 3, metabotropic glutamate receptor; GPCR, family 3, nine cysteines domain; Periplasmic binding protein-like I; Receptor, ligand binding region. Its molecular function is described by: G-protein coupled receptor activity; glutamate receptor activity. It is involved in the biological process described with: adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway; adult feeding behavior; phospholipase C-activating G-protein coupled receptor signaling pathway; regulation of synaptic transmission, glutamatergic; response to insecticide. 17 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: feeding behavior defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0035461	ntc	0.496921736	0.201420464	0.999936032	NA	NA	NA	NA	NA	NA	"The gene nutcracker is referred to in FlyBase by the symbol Dmel\ntc (CG10855, FBgn0035461). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:3803832..3806459. It has the cytological map location 63F1. Protein features are: F-box domain. Its molecular function is described by: ubiquitin-protein transferase activity. It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; activation of cysteine-type endopeptidase activity involved in apoptotic process; sperm individualization; protein stabilization. 16 alleles are reported. The phenotypes of these alleles manifest in: sperm individualization complex; cystic bulge; individualization stage spermatid. The phenotypic classes of alleles include: sterile; male sterile; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed in adult male stages.  "
FBgn0013984	InR	0.498188053	0.18958644	0.999936032	NA	IGF1R;INSR;INSRR	high;moderate;moderate	NA	transmembrane protein	NA	NA
FBgn0010039	GstD3	0.498233843	0.172034599	0.999936032	NA	GSTT2B;GSTT1;MARS;VARS;GSTT2;EEF1G;EEF1E1	low;low;low;low;low;low;low	NA	NA	NA	"The gene Glutathione S transferase D3 is referred to in FlyBase by the symbol Dmel\GstD3 (CG4381, FBgn0010039). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:12373068..12373813. It has the cytological map location 87B8. Protein features are: Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Thioredoxin-like fold. Its molecular function is described by: glutathione transferase activity. It is involved in the biological process described with: glutathione metabolic process. 2 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: viable; body color defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed at stages throughout the pupal period.  "
FBgn0035644	DNApol-epsilon58	0.499677631	0.119425996	0.999936032	NA	POLE2	high	NA	NA	NA	"The gene DNA polymerase ‘µ 58kD subunit is referred to in FlyBase by the symbol Dmel\DNApol-‘µ58 (CG10489, FBgn0035644). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:5895691..5897435. It has the cytological map location 64F4. Protein features are: DNA polymerase alpha/epsilon, subunit B; DNA polymerase epsilon subunit B, N-terminal; DNA polymerase epsilon, subunit B. Its molecular function is described by: DNA binding; DNA-directed DNA polymerase activity. It is involved in the biological process described with: cellular response to DNA damage stimulus; positive regulation of cell cycle process; positive regulation of DNA endoreduplication; error-prone translesion synthesis. 6 alleles are reported. The phenotypes of these alleles manifest in: wing disc; ventral thoracic disc; nucleus; wing; eye disc; embryonic/larval salivary gland; embryonic/larval brain; trichogen cell. The phenotypic classes of alleles include: cell cycle defective; flight defective; phenotype; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0030090	fend	0.500066777	0.231395699	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene forked end is referred to in FlyBase by the symbol Dmel\fend (CG12664, FBgn0030090). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:9121973..9135099. It has the cytological map location 8C11-8C13. Its molecular function is unknown. It is involved in the biological process described with: motor neuron axon guidance. 17 alleles are reported. The phenotypes of these alleles manifest in: intersegmental nerve; motor neuron; mesothoracic tergum; embryonic/larval neuromuscular junction. The phenotypic classes of alleles include: increased mortality; increased mortality during development; phenotype; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0036749	CG7460	0.500374967	0.1812057	0.999936032	NA	PAOX;SMOX	moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7460 (FBgn0036749). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:17740540..17742540. It has the cytological map location 74F4-75A1. Protein features are: Amine oxidase; FAD/NAD(P)-binding domain. Its molecular function is described by: oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 06-18 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0058160	CG40160	0.501968062	0.174167903	0.999936032	NA	KLK1;KLKB1;KLK3;F11;KLK11;KLK2;TPSAB1;F9	low;low;low;low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG40160 (FBgn0058160). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (1 unique). Gene sequence location is 3L:26215815..26229433. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0032018	CG7806	0.501968477	0.183399543	0.999936032	ABCC10	ABCC10;ABCC8;ABCC9;ABCC4;ABCC6;ABCC2;ABCC3;ABCC1;ABCC12;ABCC11;ABCC5	high;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7806 (FBgn0032018). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:8311399..8317011. It has the cytological map location 29A3-29A4. Protein features are: AAA+ ATPase domain; ABC transporter type 1, transmembrane domain; ABC transporter, conserved site; ABC transporter-like; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: ATP binding; ATPase activity, coupled to transmembrane movement of substances. It is involved in the biological process described with: transmembrane transport. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.  "
FBgn0035727	CG10063	0.501973764	0.140884751	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG10063 (FBgn0035727). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:6971579..6972467. It has the cytological map location 65D5. Its molecular function is described by: . It is involved in the biological process described with: . 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; flightless; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed in adult male stages.
FBgn0037856	Leash	0.502035609	0.232270419	0.999936032	NA	ARRDC2;ARRDC4;TXNIP;ARRDC3;ARRDC1;ARRDC5	moderate;moderate;moderate;moderate;low;moderate	NA	NA	NA	"The gene Leash is referred to in FlyBase by the symbol Dmel\Leash (CG4674, FBgn0037856). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:10885540..10896418. It has the cytological map location 86C7. Protein features are: Arrestin C-terminal-like domain; Arrestin-like, N-terminal; Immunoglobulin E-set. Its molecular function is unknown. It is involved in the biological process described with: regulation of hippo signaling. 21 alleles are reported. The phenotypes of these alleles manifest in: neurite; wing. The phenotypic classes of alleles include: viable; lethal - all die before end of larval stage; fertile; size defective; some die during larval stage; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0264305	CG43783	0.50235176	0.215129115	0.999936032	NA	TEX2	high	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG43783 (FBgn0264305). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (all unique). Gene sequence location is 3L:8932235..8954272. It has the cytological map location 66E4-66E5. Protein features are: MMM1 domain. Its molecular function is described by: lipid binding. The biological processes in which it is involved are not known. 13 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable.
FBgn0038482	CG4053	0.502443363	0.160535634	0.999936032	NA	KLK14;KLK6	low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4053 (FBgn0038482). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:17131211..17132198. It has the cytological map location 89F1. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  No temporal expression data available due to processing error.  This will be corrected the next time these data and summaries are processed."
FBgn0038147	CCHa2	0.502924061	0.165458008	0.999936032	NA	NA	NA	NA	NA	NA	"The gene CCHamide-2 is referred to in FlyBase by the symbol Dmel\CCHa2 (CG14375, FBgn0038147). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:13389059..13395197. It has the cytological map location 87E8. Its molecular function is described by: neuropeptide hormone activity. It is involved in the biological process described with: neuropeptide signaling pathway. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: mating behavior defective; body size defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0262524	ver	0.504531251	0.228053978	0.999936032	NA	NA	NA	NA	NA	NA	"The gene verrocchio is referred to in FlyBase by the symbol Dmel\ver (CG14121, FBgn0262524). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:12523987..12525150. It has the cytological map location 69C4. Its molecular function is described by: single-stranded telomeric DNA binding. It is involved in the biological process described with: telomere capping; telomere maintenance. 17 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; chromosome, telomeric region; chromosome. The phenotypic classes of alleles include: increased mortality during development; phenotype; increased mortality; lethal - all die before end of P-stage."
FBgn0046302	CG10650	0.504581323	0.150228417	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG10650 (FBgn0046302). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:18993360..18995934. It has the cytological map location 37B8. Protein features are: Domain of unknown function DUF753. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late larval stages.
FBgn0037142	CG14562	0.506144152	0.181739236	0.999936032	NA	HPS3	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14562 (FBgn0037142). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:21942221..21949866. It has the cytological map location 79A4. Protein features are: Hermansky-Pudlak syndrome 3 protein, N-terminal domain; Hermansky-Pudlak syndrome 3, central region; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0034856	yellow-d2	0.506296265	0.11571172	0.999936032	NA	NA	NA	NA	NA	NA	"The gene yellow-d2 is referred to in FlyBase by the symbol Dmel\yellow-d2 (CG9891, FBgn0034856). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:23381197..23382591. It has the cytological map location 59D9. Protein features are: Major royal jelly protein/protein yellow; Six-bladed beta-propeller, TolB-like. Its molecular function is unknown. It is involved in the biological process described with: cuticle pigmentation; melanin biosynthetic process. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during late larval stages, during late pupal stages.  "
FBgn0039064	CG4467	0.506420951	0.200246533	0.999936032	NA	ERAP1;ERAP2;LNPEP;ENPEP;TRHDE;LVRN;ANPEP	high;high;high;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4467 (FBgn0039064). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:23227727..23248903. It has the cytological map location 94E7-94E8. Protein features are: ERAP1-like C-terminal domain; Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase; Peptidase M1, membrane alanine aminopeptidase, N-terminal. Its molecular function is described by: zinc ion binding; metalloaminopeptidase activity; peptide binding. It is involved in the biological process described with: peptide catabolic process; proteolysis. 11 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-18 embryonic stages.  "
FBgn0036844	Mkp3	0.50667839	0.183632388	0.999936032	NA	DUSP7;DUSP6;DUSP9;SSH3;SSH2;DUSP8;DUSP4;DUSP18;DUSP16;DUSP1	high;moderate;moderate;low;low;low;low;low;low;low	NA	NA	NA	"The gene Mitogen-activated protein kinase phosphatase 3 is referred to in FlyBase by the symbol Dmel\Mkp3 (CG14080, FBgn0036844). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 3L:19066155..19086426. It has the cytological map location 75F6. Protein features are: Dual specificity phosphatase; Dual specificity phosphatase, catalytic domain; Dual specificity protein phosphatase domain; Mitogen-activated protein (MAP) kinase phosphatase; Protein-tyrosine phosphatase-like; Rhodanese-like domain; Tyrosine specific protein phosphatases domain. Its molecular function is described by: MAP kinase tyrosine/serine/threonine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity; phosphatase activity. It is involved in the biological process described with: negative regulation of MAPK cascade; imaginal disc-derived wing vein specification; mucosal immune response; protein dephosphorylation; regulation of cell proliferation; cell-cell adhesion; primary branching, open tracheal system; maintenance of epithelial integrity, open tracheal system. 50 alleles are reported. The phenotypes of these alleles manifest in: photoreceptor cell R4; chaeta; photoreceptor cell R7; eo-type sensillum; adult external mesothorax; inner photoreceptor cell; mechanosensory chaeta; epithelium; tracheal system; macrochaeta; dorsal branch primordium; adult gut. The phenotypic classes of alleles include: phenotype; increased mortality during development; increased mortality; cell shape defective; lethal - all die before end of pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during late pupal stages, in adult female stages.  "
FBgn0026084	cib	0.507772336	0.153616909	0.999936032	NA	TMSB4X;TMSB10;TMSB4Y	high;moderate;moderate	NA	NA	NA	"The gene ciboulot is referred to in FlyBase by the symbol Dmel\cib (CG4944, FBgn0026084). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (2 unique). Gene sequence location is X:4106113..4110981. It has the cytological map location 4A5. Protein features are: Beta-thymosin. Its molecular function is described by: actin monomer binding; actin binding. It is involved in the biological process described with: brain development; larval central nervous system remodeling; actin filament organization. 20 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; mushroom body beta-lobe; ellipsoid body; sarcomere; Z disc. The phenotypic classes of alleles include: lethal - all die during larval stage; body color defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of moderate expression.  Peak expression observed during early pupal stages.  "
FBgn0039818	CG11318	0.507960585	0.165837086	0.999936032	NA	ADGRG7;ADGRG2;ADGRF1;ADGRD2;ADGRF3;ADGRF4;ADGRF5;ADGRF2;ADGRG4	high;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate	NA	transmembrane protein	GPCR	"This gene is referred to in FlyBase by the symbol Dmel\CG11318 (FBgn0039818). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:31106362..31109191. It has the cytological map location 100B2-100B3. Protein features are: GPCR, family 2, secretin-like; GPCR, family 2-like; GPS motif. Its molecular function is described by: G-protein coupled receptor activity. It is involved in the biological process described with: G-protein coupled receptor signaling pathway; cell surface receptor signaling pathway. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0030773	CG9676	0.509676057	0.182155774	0.999936032	NA	KLK15;KLK9	low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9676 (FBgn0030773). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:16699152..16700170. It has the cytological map location 15A1. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 5 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; lethal - all die during P-stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed in adult male stages.  "
FBgn0035923	CG6511	0.510839504	0.213347959	0.999936032	EDRF1	EDRF1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6511 (FBgn0035923). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:8721324..8726108. It has the cytological map location 66D11-66D12. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0040575	CG15922	0.511432789	0.178745422	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15922 (FBgn0040575). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:20559708..20560280. It has the cytological map location 92F1. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0001941	ifc	0.511495147	0.146791015	0.999936032	DEGS2	DEGS2;DEGS1	high;moderate	NA	transmembrane protein	NA	"The gene infertile crescent is referred to in FlyBase by the symbol Dmel\ifc (CG9078, FBgn0001941). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:5986348..5988854. It has the cytological map location 26B2. Protein features are: Fatty acid desaturase domain; Sphingolipid delta4-desaturase; Sphingolipid delta4-desaturase, N-terminal. Its molecular function is described by: sphingolipid delta-4 desaturase activity. It is involved in the biological process described with: spindle assembly involved in male meiosis; spermatogenesis; ceramide biosynthetic process; phototransduction; photoreceptor cell maintenance. 33 alleles are reported. The phenotypes of these alleles manifest in: intracellular organelle; microtubule cytoskeleton; organelle; adult adipose system; meiotic cell cycle; intracellular; cell cycle; multi-tissue structure; reproduction; male germline cyst. The phenotypic classes of alleles include: cell cycle defective; increased mortality; starvation stress response defective; phenotype; male sterile; increased mortality during development; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, in adult female stages.  "
FBgn0264845	Tep5	0.511671344	0.207188816	0.999936032	NA	CD109;A2M;C3;C4B;C4A;C5	moderate;moderate;low;low;low;low	NA	NA	NA	"The gene Thioester-containing protein 5 is referred to in FlyBase by the symbol Dmel\Tep5 (CG13079, FBgn0264845). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:19558047..19563049. It has the cytological map location 37F1-37F2. Protein features are: Alpha-2-macroglobulin; Alpha-macroglobulin complement component; Alpha-macroglobulin, receptor-binding; Immunoglobulin-like fold; Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid. Its molecular function is described by: endopeptidase inhibitor activity. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. No phenotypic class data is available."
FBgn0037000	ZnT77C	0.512060378	0.190096549	0.999936032	NA	SLC30A1;SLC30A10	moderate;low	NA	transmembrane protein	NA	"The gene Zinc transporter 77C is referred to in FlyBase by the symbol Dmel\ZnT77C (CG5130, FBgn0037000). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:20484293..20494921. It has the cytological map location 77C4-77C6. Protein features are: Cation efflux protein; Cation efflux protein, cytoplasmic domain. Its molecular function is described by: zinc efflux transmembrane transporter activity; zinc ion transmembrane transporter activity. It is involved in the biological process described with: regulation of sequestering of zinc ion; zinc II ion transmembrane transport; detoxification of zinc ion. 12 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, during late larval stages.  "
FBgn0265369	CR44310	0.512150565	0.184012663	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44310 (FBgn0265369). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2L:3616296..3617619. It has the cytological map location 24A1. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0033204	CG2065	0.512342125	0.190942979	0.999936032	RDH11	RDH11;RDH12;RDH13;RDH14;DHRS13;DHRSX;DHRS12	high;high;moderate;moderate;low;low;moderate	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG2065 (FBgn0033204). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:7663786..7665269. It has the cytological map location 43E8-43E9. Protein features are: NAD(P)-binding domain; Short-chain dehydrogenase/reductase SDR. Its molecular function is described by: oxidoreductase activity. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages.
FBgn0085419	Rgk2	0.513632396	0.194129235	0.999936032	NA	REM1;RRAD;REM2;GEM	high;moderate;moderate;moderate	NA	NA	NA	"The gene Rad, Gem/Kir family member 2 is referred to in FlyBase by the symbol Dmel\Rgk2 (CG34390, FBgn0085419). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:18539585..18548969. It has the cytological map location 55D3. Protein features are: P-loop containing nucleoside triphosphate hydrolase; Small GTPase superfamily; Small GTPase superfamily, Ras type. Its molecular function is described by: GTPase activity; GTP binding. It is involved in the biological process described with: negative regulation of voltage-gated calcium channel activity; small GTPase mediated signal transduction; signal transduction. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed during early pupal stages.  "
FBgn0028408	Drep2	0.51368258	0.21747707	0.999936032	NA	CIDEC;CIDEA;DFFA;CIDEB	high;low;low;low	NA	NA	NA	"The gene DNA fragmentation factor-related protein 2 is referred to in FlyBase by the symbol Dmel\Drep2 (CG1975, FBgn0028408). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 2R:9291856..9302821. It has the cytological map location 45C4-45C5. Protein features are: CIDE-N domain. Its molecular function is unknown. It is involved in the biological process described with: negative regulation of neuron death; regulation of apoptotic process. 26 alleles are reported. The phenotypes of these alleles manifest in: Z disc; sarcomere; ganglion mother cell; embryonic/larval neuroblast; mesothoracic tergum. The phenotypic classes of alleles include: phenotype; increased mortality during development; increased mortality; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0034976	CG4049	0.514472281	0.220698112	0.999936032	NA	RAD54L2	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG4049 (FBgn0034976). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:24107087..24114292. It has the cytological map location 60B10. Protein features are: Helicase superfamily 1/2, ATP-binding domain; Helicase, C-terminal; P-loop containing nucleoside triphosphate hydrolase; SNF2-related, N-terminal domain. Its molecular function is described by: ATP binding. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0039154	Npc2f	0.51572253	0.143673835	0.999936032	NA	NPC2	moderate	NA	NA	NA	"The gene Niemann-Pick type C-2f is referred to in FlyBase by the symbol Dmel\Npc2f (CG6164, FBgn0039154). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:24137895..24140936. It has the cytological map location 95E1. Protein features are: Immunoglobulin E-set; MD-2-related lipid-recognition domain; ML domain, Npc2 like. Its molecular function is described by: sterol binding. It is involved in the biological process described with: sterol transport; intracellular cholesterol transport. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during late larval stages.  "
FBgn0029155	Men-b	0.515946967	0.147362244	0.999936032	NA	ME3;ME1;ME2	high;moderate;moderate	NA	NA	NA	"The gene Malic enzyme b is referred to in FlyBase by the symbol Dmel\Men-b (CG5889, FBgn0029155). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 3R:27151662..27157603. It has the cytological map location 97E5. Protein features are: Malic enzyme, N-terminal domain; Malic enzyme, NAD-binding; Malic enzyme, conserved site; Malic oxidoreductase; NAD(P)-binding domain. Its molecular function is described by: NAD binding; malate dehydrogenase (decarboxylating) (NAD+) activity; malate dehydrogenase (decarboxylating) (NADP+) activity. It is involved in the biological process described with: oxidation-reduction process; pyruvate metabolic process; malate metabolic process; regulation of glucose metabolic process. 21 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: flight defective; viable; fertile; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late pupal stages.  "
FBgn0036952	CG6933	0.516687056	0.205219184	0.999936032	NA	MATN2	low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6933 (FBgn0036952). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is 3L:20218500..20220420. It has the cytological map location 77A2. Protein features are: Chitin binding domain. Its molecular function is described by: chitin binding. It is involved in the biological process described with: chitin metabolic process. 5 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: body color defective; viable; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0058439	CG40439	0.51686121	0.159048309	0.999936032	NA	COMMD8	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG40439 (FBgn0058439). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:22797519..22798276. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 06-18 hour embryonic stages.
FBgn0262607	CG43133	0.516935705	0.131235248	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG43133 (FBgn0262607). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:18129585..18130178. It has the cytological map location 16F7. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported.
FBgn0039205	CG13623	0.517159985	0.176981064	0.999936032	NA	ISCA2	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13623 (FBgn0039205). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:24529773..24530558. It has the cytological map location 96A6. Protein features are: FeS cluster biogenesis; FeS cluster insertion protein. Its molecular function is described by: structural molecule activity; iron ion binding; 4 iron, 4 sulfur cluster binding; 2 iron, 2 sulfur cluster binding. It is involved in the biological process described with: protein maturation; protein maturation by iron-sulfur cluster transfer; iron-sulfur cluster assembly; lateral inhibition. 4 alleles are reported. The phenotypes of these alleles manifest in: chaeta; trichogen cell. The phenotypic classes of alleles include: phenotype; viable; visible; short lived; increased mortality; some die during P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0051810	CG31810	0.517379266	0.149008355	0.999936032	NA	HSDL1;HSD17B12;HSD17B3	high;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31810 (FBgn0051810). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:16849018..16852368. It has the cytological map location 36B2. Protein features are: NAD(P)-binding domain; Short-chain dehydrogenase/reductase SDR. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, in adult male stages.  "
FBgn0004429	LysP	0.517802912	0.209693821	0.999936032	NA	LYZ;SPACA5B;LYZL1;SPACA3;LALBA;SPACA5;LYZL2;LYZL4;LYZL6	high;low;low;low;low;low;low;low;low	NA	NA	NA	"The gene Lysozyme P is referred to in FlyBase by the symbol Dmel\LysP (CG9116, FBgn0004429). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:1218082..1218696. It has the cytological map location 61F4. Protein features are: Glycoside hydrolase, family 22; Glycoside hydrolase, family 22, conserved site; Glycoside hydrolase, family 22, lysozyme; Lysozyme-like domain. Its molecular function is described by: lysozyme activity. It is involved in the biological process described with: defense response to Gram-positive bacterium; defense response to Gram-negative bacterium; cell wall macromolecule catabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed in adult female stages.  "
FBgn0037635	CG9837	0.518175786	0.161311776	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG9837 (FBgn0037635). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:8807679..8813579. It has the cytological map location 85B2. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during early pupal stages.
FBgn0030060	CG2004	0.518838132	0.150901265	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG2004 (FBgn0030060). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is X:8712472..8714924. It has the cytological map location 8A2. Protein features are: CHK kinase-like; Protein kinase-like domain; Protein of unknown function DUF227. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, during early larval stages.  "
FBgn0053868	His2B:CG33868	0.519429734	0.214967244	0.999936032	HIST1H2BJ	HIST1H2BO;HIST3H2BB;HIST1H2BB;HIST2H2BE;HIST1H2BE;HIST1H2BA;HIST1H2BJ;HIST1H2BH;HIST1H2BN;HIST1H2BK;HIST1H2BL;HIST1H2BC;HIST2H2BF;HIST1H2BG;HIST1H2BM;HIST1H2BI;HIST1H2BF;HIST1H2BD	moderate;moderate;low;low;moderate;low;low;low;low;low;low;moderate;low;moderate;low;moderate;moderate;low	NA	NA	NA	"The gene His2B:CG33868 is referred to in FlyBase by the symbol Dmel\His2B:CG33868 (CG33868, FBgn0053868). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:21537505..21538099. It has the cytological map location 39E1. Protein features are: Histone H2A/H2B/H3; Histone H2B; Histone-fold. Its molecular function is described by: protein heterodimerization activity; DNA binding. It is involved in the biological process described with: chromatin assembly or disassembly. 9 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  No expression detected at any stage of development.  CAVEAT: These RNA-Seq temporal profiles depend upon RNA-Seq reads that are uniquely placed in the genome.  For this reason, genes such as histones, Stellates and many classes of RNA genes that are present in multiple exact or near exact copies in the genome, expression levels may be reported as much lower than their true values."
FBgn0030836	CG8664	0.519533281	0.202368972	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG8664 (FBgn0030836). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:17280918..17282726. It has the cytological map location 15F7. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: flightless; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of extremely low expression.  Peak expression observed during late larval stages.
FBgn0003996	w	0.519967169	0.162176901	0.999936032	NA	ABCG2;ABCG4;ABCG1;ABCG8	high;low;low;low	NA	transmembrane protein	NA	"The gene white is referred to in FlyBase by the symbol Dmel\w (CG2759, FBgn0003996). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:2790599..2796466. It has the cytological map location 3B6. Protein features are: AAA+ ATPase domain; ABC transporter, conserved site; ABC transporter-like; ABC-2 type transporter; P-loop containing nucleoside triphosphate hydrolase; Pigment precursor permease. Its molecular function is described by: eye pigment precursor transporter activity; synaptic vesicle amine transmembrane transporter activity; guanine-transporting ATPase activity; ATP binding; 3',5'-cyclic GMP transmembrane-transporting ATPase activity. It is involved in the biological process described with 12 unique terms, many of which group under: behavior; amine metabolic process; compound eye pigmentation; histamine uptake; locomotion; multi-organism process; transmembrane transport; neurological system process; gravitaxis; amine transport. 2317 alleles are reported. The phenotypes of these alleles manifest in: epithelium; pigment granule; pigment cell; gonad; acellular anatomical structure; excretory system; reproductive system; testis; testis sheath; photoreceptor cell; gonadal sheath; Malpighian tubule segment; embryonic/larval excretory system. The phenotypic classes of alleles include: phenotype; visible; fertile; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during late larval stages, at stages throughout the pupal period.  "
FBgn0035754	MED4	0.520558234	0.198460793	0.999936032	MED4	MED4	high	Co-factor	NA	NA	"The gene Mediator complex subunit 4 is referred to in FlyBase by the symbol Dmel\MED4 (CG8609, FBgn0035754). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:7249529..7250527. It has the cytological map location 65E9. Protein features are: Mediator complex, subunit Med4. Its molecular function is described by: RNA polymerase II transcription cofactor activity; transcription coactivator activity; protein binding. It is involved in the biological process described with: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; mitotic G2 DNA damage checkpoint; muscle organ development; dendrite morphogenesis; negative regulation of neuroblast proliferation. 4 alleles are reported. The phenotypes of these alleles manifest in: spermatocyte; mesothoracic tergum; neuroblast. The phenotypic classes of alleles include: neuroanatomy defective; meiotic cell cycle defective; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0030029	CG15343	0.521224477	0.207272383	0.999936032	NA	PNPO	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15343 (FBgn0030029). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:8272324..8273806. It has the cytological map location 7E1. Protein features are: FMN-binding split barrel; Pyridoxamine 5'-phosphate oxidase; Pyridoxamine 5'-phosphate oxidase, putative. Its molecular function is described by: FMN binding; pyridoxamine-phosphate oxidase activity. It is involved in the biological process described with: pyridoxine biosynthetic process; pyridoxal phosphate biosynthetic process. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0028841	jhamt	0.52143553	0.21395803	0.999936032	NA	NA	NA	NA	NA	NA	"The gene juvenile hormone acid methyltransferase is referred to in FlyBase by the symbol Dmel\jhamt (CG17330, FBgn0028841). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:16365903..16367039. It has the cytological map location 35F12. Protein features are: Methyltransferase type 12; S-adenosyl-L-methionine-dependent methyltransferase. Its molecular function is described by: juvenile hormone acid methyltransferase activity; farnesoic acid O-methyltransferase activity. It is involved in the biological process described with: male courtship behavior; juvenile hormone biosynthetic process. 8 alleles are reported. The phenotypes of these alleles manifest in: ovary; male genitalia. The phenotypic classes of alleles include: phenotype; increased mortality during development; viable; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0263081	CG43349	0.521609857	0.139478659	0.999936032	NA	PHGR1	low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG43349 (FBgn0263081). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:1200205..1200663. It has the cytological map location 21F2. Its molecular function is described by: . It is involved in the biological process described with: . One allele is reported. No phenotypic data is available. No phenotypic class data is available.
FBgn0261859	CG42788	0.522673231	0.209927945	0.999936032	NA	FRMPD4;FRMPD1;FRMPD3	high;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG42788 (FBgn0261859). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:15095957..15131926. It has the cytological map location 88E1-88E2. Protein features are: Band 4.1 domain; FERM central domain; FERM domain; FERM/acyl-CoA-binding protein, 3-helical bundle; PDZ domain; Ubiquitin-related domain; WW domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 17 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable."
FBgn0034140	Lst	0.52286255	0.210859708	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene Limostatin is referred to in FlyBase by the symbol Dmel\Lst (CG8317, FBgn0034140). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 2R:16574579..16576586. It has the cytological map location 53C8. Its molecular function is unknown. It is involved in the biological process described with: glucose homeostasis; regulation of calcium-mediated signaling; cellular response to starvation; cellular response to carbohydrate stimulus; triglyceride homeostasis; negative regulation of peptide hormone secretion. 11 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: short lived; developmental rate defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late larval stages.  "
FBgn0086708	stv	0.52342365	0.153482689	0.999936032	NA	BAG3;BAG4;BAG5	high;moderate;moderate	NA	NA	NA	"The gene starvin is referred to in FlyBase by the symbol Dmel\stv (CG32130, FBgn0086708). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (5 unique). Gene sequence location is 3L:13477541..13483515. It has the cytological map location 70B2. Protein features are: BAG domain. Its molecular function is described by: heat shock protein binding; chaperone binding. It is involved in the biological process described with: lateral inhibition; positive regulation of protein lipidation. 20 alleles are reported. The phenotypes of these alleles manifest in: Z disc; chaeta; mesothoracic tergum. The phenotypic classes of alleles include: phenotype; visible; increased mortality; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the pupal period.  "
FBgn0263005	CG43313	0.524298507	0.202570982	0.999936032	NA	CHPF;CHPF2;MIR671	high;moderate;moderate	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG43313 (FBgn0263005). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:13095571..13112462. It has the cytological map location 11D11-11E1. Protein features are: Chondroitin N-acetylgalactosaminyltransferase. Its molecular function is described by: acetylgalactosaminyltransferase activity. It is involved in the biological process described with: sensory perception of pain. 13 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; fertile; viable; pain response defective.
FBgn0030858	IntS2	0.524671385	0.186154136	0.999936032	INTS2	INTS2	high	NA	NA	NA	"The gene Integrator 2 is referred to in FlyBase by the symbol Dmel\IntS2 (CG8211, FBgn0030858). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:17652761..17656818. It has the cytological map location 16B10. Protein features are: Integrator complex subunit 2; Integrator complex subunit 2, metazoa. Its molecular function is described by: . It is involved in the biological process described with: snRNA processing; snRNA 3'-end processing. 5 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; embryonic/larval neuroblast. The phenotypic classes of alleles include: partially lethal - majority die; neuroanatomy defective; lethal - all die during P-stage; viable; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0262872	milt	0.525723799	0.154605932	0.999936032	NA	TRAK1;TRAK2;HAP1	high;moderate;moderate	NA	NA	NA	"The gene milton is referred to in FlyBase by the symbol Dmel\milt (CG43227, FBgn0262872). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (4 unique). Gene sequence location is 2L:7037823..7056010. It has the cytological map location 27D6. Protein features are: HAP1, N-terminal; Trafficking kinesin-binding protein domain. Its molecular function is described by: myosin binding; microtubule motor activity. It is involved in the biological process described with: establishment of mitochondrion localization; oocyte dorsal/ventral axis specification; sperm mitochondrion organization; mitochondrion distribution; phototransduction; Nebenkern assembly; axonal transport of mitochondrion. 27 alleles are reported. The phenotypes of these alleles manifest in: cell part; neuron; glial cell; intracellular vesicle; intracellular; photoreceptor cell; axon; thoracic segment; cell projection; neuron part. The phenotypic classes of alleles include: some die during larval stage; increased mortality; increased mortality during development; phenotype."
FBgn0032283	CG7296	0.526178667	0.208660412	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7296 (FBgn0032283). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:10686124..10687066. It has the cytological map location 32A4. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; chaeta. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; body color defective; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0052767	CG32767	0.526314066	0.175907377	0.999936032	NA	ZNF592;ZNF692;ZFP91	low;low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG32767 (FBgn0052767). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (2 unique). Gene sequence location is X:5071027..5084768. It has the cytological map location 4E2. Protein features are: Tim10/FAM136A-like domain; WD40/YVTN repeat-like-containing domain; Zinc finger C2H2-type. Its molecular function is described by: nucleic acid binding. The biological processes in which it is involved are not known. 12 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0000210	br	0.526613314	0.210067076	0.999936032	NA	ZBTB49;MYNN;ZBTB14;ZBTB41;ZBTB39;ZBTB24	low;low;low;low;low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	NA
FBgn0265186	CG44251	0.526890903	0.138906681	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG44251 (FBgn0265186). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:12948348..12952293. It has the cytological map location 49E4. Protein features are: DM9 repeat; Domain of unknown function DUF3421. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported.
FBgn0042094	Adk3	0.527327265	0.172842719	0.999936032	NA	AK3;AK4;AK2	high;moderate;low	NA	NA	NA	"The gene Adenylate kinase 3 is referred to in FlyBase by the symbol Dmel\Adk3 (CG6612, FBgn0042094). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 3R:10887345..10889588. It has the cytological map location 86C7. Protein features are: Adenylate kinase 3/4, mitochondrial; Adenylate kinase subfamily; Adenylate kinase, active site lid domain; Adenylate kinase, conserved site; Adenylate kinase/UMP-CMP kinase; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: adenylate kinase activity; nucleoside triphosphate adenylate kinase activity; ATP binding. It is involved in the biological process described with: ADP biosynthetic process. 8 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; short lived; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult male stages.  "
FBgn0005612	Sox14	0.528984622	0.162844721	0.999936032	NA	SOX12;SOX4;SOX11	high;moderate;moderate	DNA-binding with transcription factor activity(HMG_box)	NA	NA	"The gene Sox box protein 14 is referred to in FlyBase by the symbol Dmel\Sox14 (CG3090, FBgn0005612). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:23978801..23985177. It has the cytological map location 60A16. Protein features are: High mobility group box domain. Its molecular function is described by: DNA binding, bending; sequence-specific DNA binding. It is involved in the biological process described with: metamorphosis; dendrite morphogenesis; regulation of neuron remodeling; regulation of transcription from RNA polymerase II promoter; neuron remodeling. 13 alleles are reported. The phenotypes of these alleles manifest in: wing; adult abdomen; mesothoracic tergum; dendrite; dorsal multidendritic neuron ddaC; anterior pupal spiracle. The phenotypic classes of alleles include: increased mortality during development; phenotype; majority die during P-stage; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0034928	CG13562	0.52900001	0.164069142	0.999936032	NA	PNLIP	low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG13562 (FBgn0034928). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:23903750..23905269. It has the cytological map location 60A9. Protein features are: Alpha/Beta hydrolase fold; Lipase/vitellogenin; Triacylglycerol lipase family. Its molecular function is described by: carboxylic ester hydrolase activity. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed during late pupal stages.
FBgn0262730	dtn	0.529897295	0.185179596	0.999936032	NA	TMEM132B;TMEM132C;TMEM132E;TMEM132D;TMEM132A	high;high;high;moderate;moderate	NA	transmembrane protein	NA	"The gene detonator is referred to in FlyBase by the symbol Dmel\dtn (CG14446, FBgn0262730). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is X:6225647..6236218. It has the cytological map location 5E1. Protein features are: Transmembrane protein 132; Transmembrane protein TMEM132, C-terminal; Transmembrane protein TMEM132, N-terminal; Transmembrane protein family 132, middle domain; WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. It is involved in the biological process described with: detection of temperature stimulus involved in sensory perception of pain. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; heat stress response defective; partially lethal - majority die; some die during pupal stage."
FBgn0000317	ck	0.533563454	0.203161208	0.999936032	NA	MYO7A;MYO7B;MYO15A;MYO10	high;moderate;low;moderate	NA	NA	NA	"The gene crinkled is referred to in FlyBase by the symbol Dmel\ck (CG7595, FBgn0000317). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2L:15044963..15057862. It has the cytological map location 35B8-35B9. Protein features are: Band 4.1 domain; FERM central domain; FERM domain; FERM/acyl-CoA-binding protein, 3-helical bundle; IQ motif, EF-hand binding site; MyTH4 domain; Myosin head, motor domain; P-loop containing nucleoside triphosphate hydrolase; PH domain-like; SH3 domain; Ubiquitin-related domain. Its molecular function is described by: actin-dependent ATPase activity; actin binding; ATPase activity, coupled; motor activity; ATP binding; myosin light chain binding; cadherin binding. It is involved in the biological process described with 11 unique terms, many of which group under: cytoskeleton organization; epidermis development; follicle cell microvillus organization; system process; larval chitin-based cuticle development; supramolecular fiber organization; sensory perception of sound; neurological system process; neurogenesis; tissue morphogenesis. 47 alleles are reported. The phenotypes of these alleles manifest in: cell part; germline cyst; somatic cell; gamete; male terminalia; ovariole; cluster of actin-based cell projections; head bristle; plasma membrane bounded cell projection; cell; trichogen cell; anatomical cluster; oocyte; dorsal hair; cell projection. The phenotypic classes of alleles include: sensory perception defective; increased mortality; phenotype; increased mortality during development; visible; lethal - all die before end of first instar larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during early larval stages.  "
FBgn0262148	CR42874	0.533709955	0.17144292	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR42874 (FBgn0262148). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2L:1989450..1990894. It has the cytological map location 22B8. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0061198	HSPC300	0.534344264	0.159453913	0.999936032	NA	BRK1	high	NA	NA	NA	"The gene Haematopoietic stem/progenitor cell protein 300 is referred to in FlyBase by the symbol Dmel\HSPC300 (CG30173, FBgn0061198). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:24027717..24028789. It has the cytological map location 60B4. Protein features are: Protein BRICK1. Its molecular function is described by: protein complex binding; protein binding. It is involved in the biological process described with: protein oligomerization; regulation of cell shape; regulation of synaptic growth at neuromuscular junction; cell motility; regulation of actin polymerization or depolymerization; positive regulation of lamellipodium assembly; positive regulation of filopodium assembly; central nervous system morphogenesis. 13 alleles are reported. The phenotypes of these alleles manifest in: longitudinal connective; presumptive embryonic/larval central nervous system; embryonic/larval neuromuscular junction; mesothoracic bristle; chaeta; ventral nerve cord commissure. The phenotypic classes of alleles include: lethal; visible; viable; neuroanatomy defective; planar polarity defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 06-12 hour embryonic stages, during early pupal stages.  "
FBgn0262731	CG33941	0.534452253	0.146863022	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG33941 (FBgn0262731). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 4:467497..471476. It has the cytological map location 102C1. Its molecular function is unknown. The biological processes in which it is involved are not known. 10 alleles are reported. No phenotypic data is available. No phenotypic class data is available.
FBgn0028532	CG7968	0.535743154	0.132460897	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG7968 (FBgn0028532). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:13849400..13850329. It has the cytological map location 34D8. Protein features are: Haemolymph juvenile hormone binding. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed during late larval stages.
FBgn0001250	if	0.535826469	0.199099231	0.999936032	ITGA8	ITGA8;ITGA2B;ITGA5;ITGAV	high;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene inflated is referred to in FlyBase by the symbol Dmel\if (CG9623, FBgn0001250). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is X:16752189..16783434. It has the cytological map location 15A5-15A7. Protein features are: FG-GAP repeat; Integrin alpha beta-propellor; Integrin alpha chain; Integrin alpha chain, C-terminal cytoplasmic region, conserved site; Integrin alpha-2; Integrin domain. Its molecular function is described by: receptor activity; protein heterodimerization activity; cell adhesion molecule binding; extracellular matrix protein binding; extracellular matrix binding. It is involved in the biological process described with 26 unique terms, many of which group under: tube morphogenesis; post-embryonic animal morphogenesis; cell adhesion; cell projection morphogenesis; sensory perception of smell; single organism cell adhesion; anatomical structure homeostasis; maintenance of location; imaginal disc-derived appendage development; instar larval or pupal development. 81 alleles are reported. The phenotypes of these alleles manifest in: multi-cell-component structure; peripheral nervous system; embryonic foregut; actin cytoskeleton; circulatory system; 3-1M; gland; compound sense organ; epithelial tube; cytoplasm; presumptive embryonic/larval central nervous system; abdominal 3 segment border muscle; abdominal 2 lateral longitudinal muscle 1; midgut constriction; border follicle cell; adult head; procuticle. The phenotypic classes of alleles include: increased mortality during development; phenotype; increased mortality; lethal - all die before end of second instar larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages.  "
FBgn0030847	CG12991	0.53587762	0.162889011	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG12991 (FBgn0030847). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (4 unique). Gene sequence location is X:17579861..17599314. It has the cytological map location 16B6-16B7. Its molecular function is unknown. The biological processes in which it is involved are not known. 9 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during early pupal stages.
FBgn0030318	rho-4	0.539253349	0.140389945	0.999936032	NA	RHBDL2;RHBDL3;RHBDL1	high;moderate;moderate	NA	transmembrane protein	NA	"The gene rhomboid-4 is referred to in FlyBase by the symbol Dmel\rho-4 (CG1697, FBgn0030318). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:11599838..11606288. It has the cytological map location 10C10. Protein features are: EF-Hand 1, calcium-binding site; EF-hand domain; EF-hand domain pair; Peptidase S54, rhomboid; Peptidase S54, rhomboid domain; Peptidase S54, rhomboid, metazoan. Its molecular function is described by: serine-type peptidase activity; serine-type endopeptidase activity; calcium ion binding. It is involved in the biological process described with: protein processing; proteolysis. 9 alleles are reported. The phenotypes of these alleles manifest in: wing; wing vein. The phenotypic classes of alleles include: viable; fertile; locomotor behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0032945	CG8665	0.542054902	0.151090302	0.999936032	ALDH1L2	ALDH1L2;ALDH1L1;ALDH8A1;ALDH2;ALDH1A2;ALDH1A3;ALDH1B1;ALDH1A1;ALDH9A1	high;high;moderate;low;low;low;low;low;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8665 (FBgn0032945). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:21371227..21377995. It has the cytological map location 39D2. Protein features are: 10-formyltetrahydrofolate dehydrogenase; Aldehyde dehydrogenase N-terminal domain; Aldehyde dehydrogenase domain; Aldehyde dehydrogenase, cysteine active site; Aldehyde dehydrogenase, glutamic acid active site; Aldehyde/histidinol dehydrogenase; Formyl transferase, C-terminal; Formyl transferase, C-terminal-like; Formyl transferase, N-terminal; Phosphopantetheine binding ACP domain; Phosphoribosylglycinamide formyltransferase, active site. Its molecular function is described by: hydroxymethyl-, formyl- and related transferase activity; formyltetrahydrofolate dehydrogenase activity; aldehyde dehydrogenase (NAD) activity. It is involved in the biological process described with: 10-formyltetrahydrofolate catabolic process; one-carbon metabolic process; oxidation-reduction process; biosynthetic process. 7 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during late larval stages.  "
FBgn0032723	ssp3	0.54340151	0.192053149	0.999936032	NA	SCAPER	high	NA	NA	NA	"The gene short spindle 3 is referred to in FlyBase by the symbol Dmel\ssp3 (CG18397, FBgn0032723). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:18916347..18943960. It has the cytological map location 37B5-37B6. Protein features are: S phase cyclin A-associated protein in the endoplasmic reticulum, N-terminal. Its molecular function is unknown. The biological processes in which it is involved are not known. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0035756	unc-13-4A	0.54340151	0.192053149	0.999936032	NA	BAIAP3;UNC13D	high;moderate	NA	NA	NA	"The gene unc-13-4A is referred to in FlyBase by the symbol Dmel\unc-13-4A (CG32381, FBgn0035756). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:7266192..7312896. It has the cytological map location 65E10-65F4. Protein features are: C2 domain; Mammalian uncoordinated homology 13, domain 2; Munc13 homology 1; WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. It is involved in the biological process described with: neurotransmitter secretion; synaptic vesicle priming. 11 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages.  "
FBgn0265596	CR44423	0.543970304	0.146723454	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44423 (FBgn0265596). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is X:15636308..15637014. It has the cytological map location 13E3. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0033636	tou	0.544058262	0.187683886	0.999936032	NA	BAZ2B;BAZ2A;BAZ1B	high;high;moderate	DNA-binding with transcription factor activity	NA	NA	"The gene toutatis is referred to in FlyBase by the symbol Dmel\tou (CG10897, FBgn0033636). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (all unique). Gene sequence location is 2R:11577485..11616045. It has the cytological map location 48A2-48A3. Protein features are: Bromodomain; Bromodomain, conserved site; DDT domain; DNA-binding domain; Methyl-CpG DNA binding; Tetratricopeptide-like helical domain; WD40/YVTN repeat-like-containing domain; WHIM1 domain; WHIM2 domain; Zinc finger, FYVE/PHD-type; Zinc finger, PHD-finger; Zinc finger, PHD-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: protein binding; transcription factor binding; DNA binding. It is involved in the biological process described with: ATP-dependent chromatin remodeling; nervous system development; positive regulation of transcription from RNA polymerase II promoter. 66 alleles are reported. The phenotypes of these alleles manifest in: dorsocentral bristle; wing; wing vein L5; scutellar bristle; trichogen cell. The phenotypic classes of alleles include: visible; viable; lethal; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0063923	Kaz1-ORFB	0.544576028	0.19504881	0.999936032	NA	SPINK14;SPINK9;SPINK7	low;low;low	NA	NA	NA	"The gene Kaz1-ORFB is referred to in FlyBase by the symbol Dmel\Kaz1-ORFB (CG1220, FBgn0063923). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3L:216625..218058. It has the cytological map location 61B2. Protein features are: Kazal domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed during late larval stages, during early pupal stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0034031	CG12963	0.54543838	0.125794581	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12963 (FBgn0034031). It is a protein_coding_gene from Drosophila melanogaster. It has 13 annotated transcripts and 13 polypeptides (all unique). Gene sequence location is 2R:15555446..15562436. It has the cytological map location 52A11-52A12. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in adult male stages.  "
FBgn0051674	CG31674	0.546178068	0.139131763	0.999936032	NA	GRHPR	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31674 (FBgn0051674). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:20831262..20832859. It has the cytological map location 38F1. Protein features are: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; NAD(P)-binding domain. Its molecular function is described by: NAD binding; glyoxylate reductase (NADP) activity; hydroxypyruvate reductase activity. It is involved in the biological process described with: oxidation-reduction process. 2 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0032048	Dh31	0.548412119	0.171803609	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene Diuretic hormone 31 is referred to in FlyBase by the symbol Dmel\Dh31 (CG13094, FBgn0032048). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:8491868..8506845. It has the cytological map location 29D1-29D3. Protein features are: Peptide hormone  DH31-like. Its molecular function is described by: diuretic hormone activity; G-protein coupled receptor binding; neuropeptide hormone activity. It is involved in the biological process described with: G-protein coupled receptor signaling pathway; positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway; body fluid secretion; positive regulation of circadian sleep/wake cycle, wakefulness; neuropeptide signaling pathway. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: circadian rhythm defective; fertile; viable; temperature response defective; sleep defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0260008	UQCR-11	0.549067757	0.124363431	0.999936032	NA	UQCRH;UQCRHL	moderate;low	NA	NA	NA	"The gene Ubiquinol-cytochrome c reductase 11 kDa subunit is referred to in FlyBase by the symbol Dmel\UQCR-11 (CG41623, FBgn0260008). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (2 unique). Gene sequence location is 3L:25120709..25126171. Protein features are: Cytochrome b-c1 complex, subunit 6; Ubiquinol-cytochrome C reductase hinge domain. Its molecular function is described by: ubiquinol-cytochrome-c reductase activity. It is involved in the biological process described with: aerobic respiration; mitochondrial electron transport, ubiquinol to cytochrome c. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.  "
FBgn0021818	cnk	0.549806292	0.166813831	0.999936032	NA	CNKSR2;CNKSR3;CNKSR1;IPCEF1	high;moderate;moderate;moderate	NA	NA	NA	"The gene connector enhancer of ksr is referred to in FlyBase by the symbol Dmel\cnk (CG6556, FBgn0021818). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:17413970..17420007. It has the cytological map location 54B7. Protein features are: CRIC domain; PDZ domain; PH domain-like; Pleckstrin homology domain; Sterile alpha motif domain; Sterile alpha motif/pointed domain. Its molecular function is described by: protein binding. It is involved in the biological process described with: imaginal disc-derived wing morphogenesis; anterior/posterior axis specification, embryo; signal transduction; tracheal outgrowth, open tracheal system; Ras protein signal transduction; positive regulation of ERK1 and ERK2 cascade; positive regulation of Ras protein signal transduction; torso signaling pathway; imaginal disc-derived wing vein morphogenesis; compound eye photoreceptor cell differentiation. 53 alleles are reported. The phenotypes of these alleles manifest in: eye photoreceptor cell; synapse; eye; imaginal disc; wing vein L4; photoreceptor cell R7; photoreceptor; wing vein; wing; dorsal air sac primordium. The phenotypic classes of alleles include: lethal - all die before end of P-stage; wild-type; some die during pupal stage; some die during P-stage; lethal; fertile; increased mortality; viable; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0035112	CG13877	0.550601466	0.148599052	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13877 (FBgn0035112). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:218068..218663. It has the cytological map location 61B2. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0030625	CG5877	0.550845255	0.18999538	0.999936032	NA	NRDE2	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5877 (FBgn0030625). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:15293031..15297169. It has the cytological map location 13B4-13B5. Protein features are: Tetratricopeptide-like helical domain; siRNA-mediated silencing protein NRDE-2. Its molecular function is unknown. It is involved in the biological process described with: chromatin silencing by small RNA; RNA interference; mRNA splicing, via spliceosome. 7 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: female sterile; lethal; fertile; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0035280	Cpr62Bb	0.553386808	0.085531148	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene Cuticular protein 62Bb is referred to in FlyBase by the symbol Dmel\Cpr62Bb (CG13935, FBgn0035280). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3L:1832636..1835164. It has the cytological map location 62B6. Protein features are: Chitin-binding type R&R consensus; Insect cuticle protein. Its molecular function is described by: structural constituent of chitin-based larval cuticle; structural constituent of cuticle. It is involved in the biological process described with: chitin-based cuticle development. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages.  "
FBgn0036240	CG6928	0.553579598	0.184553129	0.999936032	NA	SLC26A11;SLC26A6;SLC26A5;SLC26A3;SLC26A9;SLC26A1;SLC26A2;SLC26A8;SLC26A4	moderate;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6928 (FBgn0036240). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3L:12003155..12008051. It has the cytological map location 68F1. Protein features are: SLC26A/SulP transporter; SLC26A/SulP transporter domain; STAS domain. Its molecular function is described by: secondary active sulfate transmembrane transporter activity; sulfate transmembrane transporter activity; chloride channel activity; oxalate transmembrane transporter activity; bicarbonate transmembrane transporter activity; anion:anion antiporter activity. It is involved in the biological process described with: sulfate transport; chloride transmembrane transport; bicarbonate transport; regulation of intracellular pH; regulation of membrane potential. 13 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages.  "
FBgn0262945	CR43264	0.554681262	0.155981854	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR43264 (FBgn0262945). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is X:5831898..5832215. It has the cytological map location 5C2. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0047334	BG642312	0.555161251	0.186302114	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene BG642312 is referred to in FlyBase by the symbol Dmel\BG642312 (CG33943, FBgn0047334). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:6232469..6233381. It has the cytological map location 65A10. Its molecular function is described by: . It is involved in the biological process described with: regulation of post-mating oviposition; multicellular organism reproduction. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed in adult male stages.  "
FBgn0025692	Lfg	0.557819127	0.118118135	0.999936032	NA	GRINA;TMBIM4;TMBIM1;FAIM2	moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene Lifeguard is referred to in FlyBase by the symbol Dmel\Lfg (CG3814, FBgn0025692). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 2R:12875164..12876966. It has the cytological map location 49D6. Protein features are: Bax inhibitor 1-related. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. The phenotype of these alleles manifest in: eye. The phenotypic classes of alleles include: locomotor behavior defective; visible; viable; short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages.  "
FBgn0086758	chinmo	0.558188133	0.182224539	0.999936032	NA	HIC2;ZBTB21;ZBTB49;BACH2;ZBTB10;ZBTB9;ZBTB12	low;low;low;low;low;low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene Chronologically inappropriate morphogenesis is referred to in FlyBase by the symbol Dmel\chinmo (CG31666, FBgn0086758). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (2 unique). Gene sequence location is 2L:1651258..1704682. It has the cytological map location 22A5-22B1. Protein features are: BTB/POZ domain; SKP1/BTB/POZ domain; Zinc finger C2H2-type. Its molecular function is described by: nucleic acid binding. It is involved in the biological process described with: male somatic sex determination; regulation of transcription from RNA polymerase II promoter; mushroom body development; nuclear import; positive regulation of actin filament polymerization; neuron development; regulation of stem cell division; eye-antennal disc development; negative regulation of protein phosphorylation. 28 alleles are reported. The phenotypes of these alleles manifest in: testis; neuroblast; pioneer neuron; somatic cell of testis; wing; mushroom body; male germline cell. The phenotypic classes of alleles include: increased mortality during development; phenotype; visible; increased mortality; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages.  "
FBgn0027596	Kank	0.559135975	0.147801311	0.999936032	NA	KANK1;KANK2;KANK4;KANK3	high;moderate;moderate;moderate	NA	NA	NA	"The gene Kank is referred to in FlyBase by the symbol Dmel\Kank (CG10249, FBgn0027596). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (all unique). Gene sequence location is 2R:14901475..14928425. It has the cytological map location 51D2. Protein features are: Ankyrin repeat; Ankyrin repeat-containing domain; Kank N-terminal motif. Its molecular function is described by: microtubule plus-end binding. It is involved in the biological process described with: neuron projection morphogenesis. 9 alleles are reported. The phenotypes of these alleles manifest in: lysosome; vacuole; embryonic/larval pericardial cell. The phenotypic classes of alleles include: viable; fertile; cell shape defective; endocytosis defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed during late pupal stages.  "
FBgn0040056	CG17698	0.559298601	0.169057094	0.999936032	NA	CAMKK1;CAMKK2	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17698 (FBgn0040056). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 3L:23737960..23749058. It has the cytological map location 80F9. Protein features are: Calcium/calmodulin-dependent/calcium-dependent protein kinase; Protein kinase domain; Protein kinase, ATP binding site; Protein kinase-like domain; Serine/threonine-protein kinase, active site. Its molecular function is described by: ATP binding; calmodulin-dependent protein kinase activity; calmodulin binding; protein serine/threonine kinase activity; calcium ion binding. It is involved in the biological process described with: protein phosphorylation; intracellular signal transduction; peptidyl-threonine phosphorylation; positive regulation of protein kinase activity; peptidyl-serine phosphorylation. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: female semi-sterile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0263445	CR43468	0.559495933	0.153263831	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR43468 (FBgn0263445). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2R:12875164..12877280. It has the cytological map location 49D6. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0052202	CG32202	0.560088111	0.169911107	0.999936032	NA	TFPT	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG32202 (FBgn0052202). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:18682184..18682860. It has the cytological map location 75D6. Protein features are: TCF3 fusion partner. Its molecular function is described by: . It is involved in the biological process described with: apoptotic process. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages.
FBgn0038975	Nrx-1	0.560811075	0.164587025	0.999936032	NA	NRXN1;NRXN3;NRXN2	high;moderate;moderate	NA	transmembrane protein	NA	"The gene Neurexin 1 is referred to in FlyBase by the symbol Dmel\Nrx-1 (CG7050, FBgn0038975). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (5 unique). Gene sequence location is 3R:22468512..22486969. It has the cytological map location 94A16-94B1. Protein features are: C-type lectin-like/link domain; Concanavalin A-like lectin/glucanase domain; EGF-like domain; Laminin G domain. Its molecular function is described by: neurexin family protein binding; protein kinase binding; neuroligin family protein binding; apolipoprotein binding; protein binding. It is involved in the biological process described with 16 unique terms, many of which group under: locomotion; regulation of locomotion; carboxylic acid transport; single-organism behavior; associative learning; regulation of clathrin-dependent endocytosis; terminal button organization; system process; monocarboxylic acid transport; positive regulation of biological process; neuromuscular junction development; presynapse assembly. 30 alleles are reported. The phenotypes of these alleles manifest in: synapse; cell; synapse part; embryonic/larval peripheral nervous system; endomembrane system; larval tagma; postsynaptic specialization; neuromuscular junction; NMJ bouton; larval head. The phenotypic classes of alleles include: phenotype; increased mortality; fertile; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0038916	dnd	0.561812589	0.140573878	0.999936032	ARL3	ARL3	high	NA	NA	NA	"The gene dead end is referred to in FlyBase by the symbol Dmel\dnd (CG6560, FBgn0038916). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:21885676..21887355. It has the cytological map location 93F14. Protein features are: P-loop containing nucleoside triphosphate hydrolase; Small GTP-binding protein domain; Small GTPase superfamily, ARF type; Small GTPase superfamily, ARF/SAR type. Its molecular function is described by: GTP binding. It is involved in the biological process described with: cilium assembly; branch fusion, open tracheal system; small GTPase mediated signal transduction. 19 alleles are reported. The phenotypes of these alleles manifest in: dorsal trunk primordium; dorsal branch primordium; terminal tracheal cell. The phenotypic classes of alleles include: visible; cell shape defective; wild-type. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed during late pupal stages.  "
FBgn0038380	CG14877	0.562016678	0.176426585	0.999936032	NA	NPR3	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14877 (FBgn0038380). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:15889194..15896078. It has the cytological map location 89A7-89A8. Protein features are: Periplasmic binding protein-like I; Receptor, ligand binding region. Its molecular function is described by: guanylate cyclase activity. It is involved in the biological process described with: cGMP biosynthetic process; signal transduction. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages, during late larval stages.  "
FBgn0051313	CG31313	0.563116955	0.179173948	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31313 (FBgn0051313). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:14566432..14567429. It has the cytological map location 88C6. Protein features are: Cystatin domain; Proteinase inhibitor I25, cystatin, conserved site. Its molecular function is described by: cysteine-type endopeptidase inhibitor activity. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed at stages throughout the larval period, at stages throughout the pupal period, in adult male stages.  "
FBgn0266177	pre-mod(mdg4)-I	0.563782147	0.151685048	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\pre-mod(mdg4)-I (CG44883, FBgn0266177). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:21355692..21359768. It has the cytological map location 93D8. Protein features are: Zinc finger, FLYWCH-type. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported."
FBgn0034670	CG13488	0.564074129	0.151339457	0.999936032	NA	NA	NA	Maybe TF	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13488 (FBgn0034670). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 2R:21951592..21952562. It has the cytological map location 58A4. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed during late larval stages, at stages throughout the pupal period.  "
FBgn0266321	CR44986	0.564378387	0.113949252	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44986 (FBgn0266321). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2L:5947647..5948397. It has the cytological map location 26A3. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0264748	CG44006	0.565061245	0.177908105	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG44006 (FBgn0264748). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:18068728..18070150. It has the cytological map location 75B6. Protein features are: Leucine-rich repeat domain, L domain-like. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available."
FBgn0038034	Cyp9f3	0.567487492	0.122613519	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Cyp9f3 is referred to in FlyBase by the symbol Dmel\Cyp9f3 (CG17875, FBgn0038034). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:12396007..12398929. It has the cytological map location 87B9. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0262570	CG43110	0.567612854	0.162744043	0.999936032	NA	CTSG;GZMB;GZMH;CMA1	low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG43110 (FBgn0262570). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:17477565..17486220. It has the cytological map location 54B16-54B17. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. One allele is reported. No phenotypic data is available. No phenotypic class data is available."
FBgn0032997	CG17486	0.567926212	0.13761172	0.999936032	NA	ASNSD1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17486 (FBgn0032997). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:4619030..4620833. It has the cytological map location 41B1. Protein features are: Asparagine synthase; Glutamine amidotransferase type 2 domain; Nucleophile aminohydrolases, N-terminal; Rossmann-like alpha/beta/alpha sandwich fold. Its molecular function is described by: asparagine synthase (glutamine-hydrolyzing) activity; protein homodimerization activity. It is involved in the biological process described with: asparagine biosynthetic process. 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0013995	Calx	0.567985594	0.135881258	0.999936032	NA	SLC8A3;SLC8A1;SLC8A2	high;high;moderate	NA	transmembrane protein	NA	"The gene Na/Ca-exchange protein is referred to in FlyBase by the symbol Dmel\Calx (CG5685, FBgn0013995). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (7 unique). Gene sequence location is 3R:20978183..21015613. It has the cytological map location 93A4-93B3. Protein features are: Na-Ca exchanger/integrin-beta4; Sodium/calcium exchanger domain, C-terminal extension; Sodium/calcium exchanger membrane region; Sodium/calcium exchanger protein. Its molecular function is described by: calcium:sodium antiporter activity; calcium ion binding. It is involved in the biological process described with: transmembrane transport; neuromuscular process controlling posture; calcium ion transport; phototransduction; response to endoplasmic reticulum stress. 23 alleles are reported. The phenotypes of these alleles manifest in: rhabdomere; eye photoreceptor cell; eye. The phenotypic classes of alleles include: uncoordinated; neuroanatomy defective; viable; neurophysiology defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0031170	CG1718	0.568108142	0.123557608	0.999936032	ABCA3	ABCA3;ABCA5;ABCA10;ABCA6;ABCA8;ABCA9;ABCA12;ABCA2;ABCA4;ABCA13;ABCA1;ABCA7	high;moderate;moderate;moderate;moderate;moderate;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG1718 (FBgn0031170). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is X:21292308..21306665. It has the cytological map location 19F3. Protein features are: AAA+ ATPase domain; ABC transporter A, ABCA; ABC transporter, conserved site; ABC transporter-like; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: ATPase activity, coupled to transmembrane movement of substances; ATP binding. It is involved in the biological process described with: lipid transport; transport. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0031974	CG12560	0.569693262	0.1212748	0.999936032	NA	GLYATL3;GLYAT;GLYATL1;GLYATL2	high;low;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12560 (FBgn0031974). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2L:8008302..8009477. It has the cytological map location 28D3. Protein features are: Acyl-CoA N-acyltransferase; FR47-like; GNAT domain. Its molecular function is described by: N-acetyltransferase activity. It is involved in the biological process described with: histone acetylation. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: short lived; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 06-24 hour embryonic stages, in adult female stages.  "
FBgn0035663	CG6462	0.569927445	0.171630082	0.999936032	NA	F2;PRSS12;ST14;TMPRSS6;F12;F9;HABP2;PLAT;MST1;F10;PLAU;PLG;HGF;TMPRSS11E;HGFAC;MASP1;MST1L	low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6462 (FBgn0035663). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:6037111..6038188. It has the cytological map location 65A3. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0033905	CG18324	0.570993148	0.126878273	0.999936032	SLC25A34	SLC25A34;SLC25A35	moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG18324 (FBgn0033905). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:14168786..14170233. It has the cytological map location 50E1. Protein features are: Mitochondrial carrier domain; Mitochondrial substrate/solute carrier. Its molecular function is described by: transmembrane transporter activity. It is involved in the biological process described with: mitochondrial transport. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 12-24 hour embryonic stages, in adult male stages.  "
FBgn0040309	Jafrac1	0.571832657	0.111229158	0.999936032	NA	PRDX1;PRDX2;PRDX3;PRDX4	high;high;low;low	NA	NA	NA	"The gene thioredoxin peroxidase 1 is referred to in FlyBase by the symbol Dmel\Jafrac1 (CG1633, FBgn0040309). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is X:13329824..13331994. It has the cytological map location 11E11. Protein features are: Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant; Peroxiredoxin, AhpC-type; Peroxiredoxin, C-terminal; Thioredoxin domain; Thioredoxin-like fold. Its molecular function is described by: thioredoxin peroxidase activity. It is involved in the biological process described with 11 unique terms, many of which group under: response to stress; metabolic process; response to stimulus; localization; response to extracellular stimulus; biological adhesion; aging; cellular catabolic process; cell adhesion; response to oxidative stress; single-organism metabolic process; response to external stimulus; cellular response to DNA damage stimulus; primary metabolic process. 22 alleles are reported. The phenotype of these alleles manifest in: germline cell. The phenotypic classes of alleles include: stress response defective; cell adhesion defective; phenotype; chemosensitive behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0052581	CG32581	0.572006643	0.131590566	0.999936032	RNF185	RNF185;RNF5	high;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32581 (FBgn0052581). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:15796908..15799162. It has the cytological map location 13F1. Protein features are: Zinc finger, RING-type; Zinc finger, RING-type, conserved site; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: ubiquitin protein ligase activity involved in ERAD pathway; zinc ion binding; ubiquitin-protein transferase activity; ubiquitin-like protein conjugating enzyme binding. It is involved in the biological process described with: ER-associated misfolded protein catabolic process; protein ubiquitination; protein ubiquitination involved in ubiquitin-dependent protein catabolic process. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed in adult male stages.  "
FBgn0266634	CR45141	0.572325728	0.166539682	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45141 (FBgn0266634). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2R:12881445..12883253. It has the cytological map location 49D7. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0053470	CG33470	0.572534642	0.173138334	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG33470 (FBgn0053470). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:13411739..13413085. It has the cytological map location 50A5. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early pupal stages, in stages of adults of both sexes.  "
FBgn0259246	brp	0.574250339	0.160701654	0.999936032	NA	ERC2;ERC1	high;moderate	DNA-binding with transcription factor activity	NA	NA	"The gene bruchpilot is referred to in FlyBase by the symbol Dmel\brp (CG42344, FBgn0259246). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (7 unique). Gene sequence location is 2R:9503765..9541565. It has the cytological map location 45E1-45E3. Protein features are: Active zone protein ELKS. Its molecular function is unknown. It is involved in the biological process described with: chemical synaptic transmission; regulation of synaptic plasticity; anesthesia-resistant memory; short-term memory; neurotransmitter secretion; maintenance of presynaptic active zone structure; adult locomotory behavior; cytoskeletal matrix organization at active zone; neuromuscular synaptic transmission. 64 alleles are reported. The phenotypes of these alleles manifest in: synaptic vesicle; synapse; t-bar; cytoskeleton of presynaptic active zone; chaeta; neuromuscular junction; embryonic/larval neuromuscular junction; mesothoracic tergum. The phenotypic classes of alleles include: increased mortality during development; phenotype; visible; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages.  "
FBgn0086254	CG6084	0.574509474	0.109266389	0.999936032	NA	AKR1B10;AKR1B1;AKR1B15;AKR1E2;AKR1D1;AKR1A1;AKR1C2;AKR1C1;AKR1C3;AKR1C4	high;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6084 (FBgn0086254). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 3L:11620535..11624381. It has the cytological map location 68C15. Protein features are: Aldo/keto reductase; Aldo/keto reductase, conserved site; NADP-dependent oxidoreductase domain. Its molecular function is described by: oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. 14 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, during early larval stages, in stages of adults of both sexes.  "
FBgn0026756	Ugt37a1	0.574637946	0.151241959	0.999936032	NA	UGT1A3;UGT2B10;UGT1A1;UGT3A1;UGT8;UGT2B4;UGT2B15;UGT2B28;UGT2A2;UGT3A2;UGT2B17;UGT2B11;UGT2A3;UGT2B7	moderate;low;low;low;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene UDP-glycosyltransferase 37a1 is referred to in FlyBase by the symbol Dmel\Ugt37a1 (CG11012, FBgn0026756). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:20372409..20374083. It has the cytological map location 38C5. Protein features are: UDP-glucuronosyl/UDP-glucosyltransferase. Its molecular function is described by: glucuronosyltransferase activity; UDP-glycosyltransferase activity. It is involved in the biological process described with: UDP-glucose metabolic process. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed during late pupal stages.  "
FBgn0038973	Pebp1	0.574957757	0.107908545	0.999936032	NA	PEBP1;PEBP4	moderate;low	NA	NA	NA	"The gene Phosphatidylethanolamine-binding protein 1 is referred to in FlyBase by the symbol Dmel\Pebp1 (CG18594, FBgn0038973). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:22466034..22466679. It has the cytological map location 94A16. Protein features are: Phosphatidylethanolamine-binding protein. Its molecular function is unknown. It is involved in the biological process described with: defense response to Gram-positive bacterium; defense response to Gram-negative bacterium; regulation of antimicrobial humoral response. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; immune response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of very low expression.  Peak expression observed during early larval stages.  "
FBgn0030593	CG9512	0.575004844	0.123456473	0.999936032	NA	CHDH	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9512 (FBgn0030593). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:14901844..14905549. It has the cytological map location 13A1. Protein features are: FAD/NAD(P)-binding domain; Glucose-methanol-choline oxidoreductase; Glucose-methanol-choline oxidoreductase, C-terminal; Glucose-methanol-choline oxidoreductase, N-terminal. Its molecular function is described by: oxidoreductase activity, acting on CH-OH group of donors; flavin adenine dinucleotide binding; oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process; ecdysteroid metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, in stages of adults of both sexes.  "
FBgn0045800	Uhg1	0.577152227	0.162556916	0.999936032	NA	NA	NA	NA	NA	NA	"The gene U snoRNA host gene 1 is referred to in FlyBase by the symbol Dmel\Uhg1 (CR32886, FBgn0045800). It is a non_protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts. Gene sequence location is 2R:17699097..17703344. It has the cytological map location 54D6-54E1. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal; male fertile; developmental rate defective; female sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 06-18 hour embryonic stages.  "
FBgn0261530	nbs	0.577664646	0.161454625	0.999936032	NA	NBN	high	NA	NA	NA	"The gene nbs is referred to in FlyBase by the symbol Dmel\nbs (CG6754, FBgn0261530). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:9720414..9723194. It has the cytological map location 67C5. Protein features are: BRCT domain; Forkhead-associated (FHA) domain; Nibrin; Nibrin, second BRCT domain; SMAD/FHA domain. Its molecular function is described by: damaged DNA binding; ATP-dependent DNA helicase activity. It is involved in the biological process described with: chromosome organization; double-strand break repair via synthesis-dependent strand annealing; telomere capping; response to caffeine; mitotic G2 DNA damage checkpoint; cellular response to DNA damage stimulus; signal transduction in response to DNA damage; intrinsic apoptotic signaling pathway in response to DNA damage; telomere maintenance; DNA duplex unwinding. 19 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; nucleus; ommatidium; chromosome, telomeric region; macrochaeta; condensed chromosome; eye; imaginal disc. The phenotypic classes of alleles include: increased mortality; lethal; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0030777	CG9672	0.578004683	0.108881376	0.999936032	NA	PROZ;PROC	low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9672 (FBgn0030777). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:16705971..16706874. It has the cytological map location 15A3. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain. Its molecular function is unknown. It is involved in the biological process described with: proteolysis. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during late larval stages.  "
FBgn0040020	MED21	0.578448598	0.147335873	0.999936032	NA	MED21	high	NA	NA	NA	"The gene Mediator complex subunit 21 is referred to in FlyBase by the symbol Dmel\MED21 (CG17397, FBgn0040020). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:25114924..25115946. Protein features are: Mediator complex, subunit Med21. Its molecular function is described by: transcription coactivator activity; protein binding; RNA polymerase II transcription cofactor activity. It is involved in the biological process described with: transcription initiation from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter. 3 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; spermatocyte. The phenotypic classes of alleles include: meiotic cell cycle defective; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages.  "
FBgn0053995	CG33995	0.579204839	0.162100427	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG33995 (FBgn0053995). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:5043270..5048365. It has the cytological map location 25C1. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed during late larval stages, during early pupal stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0036837	CG18135	0.579737947	0.107207041	0.999936032	NA	GPCPD1	moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG18135 (FBgn0036837). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (all unique). Gene sequence location is 3L:18990026..18998283. It has the cytological map location 75F2. Protein features are: Carbohydrate binding module family 20; Carbohydrate-binding-like fold; Glycerophosphocholine phosphodiesterase GPCPD1, CBM20 domain; Glycerophosphodiester phosphodiesterase Gde1; Glycerophosphodiester phosphodiesterase domain; Immunoglobulin-like fold; PLC-like phosphodiesterase, TIM beta/alpha-barrel domain; Phosphatidylinositol-specific phospholipase C, X domain. Its molecular function is described by: glycerophosphodiester phosphodiesterase activity; glycerophosphocholine phosphodiesterase activity; starch binding; myosin binding. It is involved in the biological process described with: glycerophospholipid catabolic process; cellular phosphate ion homeostasis; multicellular organism reproduction. 13 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed in adult male stages.  "
FBgn0265533	CR44383	0.580348325	0.148620953	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44383 (FBgn0265533). It is a pseudogene_attribute from Drosophila melanogaster. It has 2 annotated transcripts. Gene sequence location is X:15796477..15796897. It has the cytological map location 13F1. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available.
FBgn0023076	Clk	0.580363173	0.163313041	0.999936032	NA	CLOCK;NPAS2;PASD1	high;moderate;moderate	DNA-binding with transcription factor activity(HLH)	NA	NA	"The gene Clock is referred to in FlyBase by the symbol Dmel\Clk (CG7391, FBgn0023076). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 3L:7763233..7775603. It has the cytological map location 66A12. Protein features are: Myc-type, basic helix-loop-helix (bHLH) domain; Nuclear translocator; PAC motif; PAS domain. Its molecular function is described by: RNA polymerase II regulatory region sequence-specific DNA binding; protein heterodimerization activity; transcription factor activity, sequence-specific DNA binding; DNA binding; chromatin binding; transcription factor binding; protein binding. It is involved in the biological process described with 14 unique terms, many of which group under: single-organism process; multicellular organismal process; positive regulation of gene expression; positive regulation of macromolecule metabolic process; regulation of circadian rhythm; rhythmic behavior; regulation of cell death; eclosion; regulation of heart contraction; response to temperature stimulus; single-organism behavior. 39 alleles are reported. The phenotypes of these alleles manifest in: larval LN period neuron; adult heart; pupal Pdf neuron; wing; head; Pdf neuron. The phenotypic classes of alleles include: circadian behavior defective; circadian rhythm defective; phenotype; increased mortality during development; increased cell death; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed in adult male stages.  "
FBgn0010040	GstD4	0.581395644	0.119667649	0.999936032	NA	GSTT2B;GSTT1;MARS;VARS;GSTT2;EEF1G;EEF1E1	low;low;low;low;low;low;low	NA	NA	NA	"The gene Glutathione S transferase D4 is referred to in FlyBase by the symbol Dmel\GstD4 (CG11512, FBgn0010040). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:12374100..12374824. It has the cytological map location 87B8. Protein features are: Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Thioredoxin-like fold. Its molecular function is described by: glutathione transferase activity. It is involved in the biological process described with: glutathione metabolic process. 2 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period.  "
FBgn0028533	CG7953	0.582529418	0.104208045	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7953 (FBgn0028533). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:13847925..13849223. It has the cytological map location 34D7-34D8. Protein features are: Haemolymph juvenile hormone binding. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the larval period, during early pupal stages, in stages of adults of both sexes.  "
FBgn0002641	mal	0.585694229	0.130365805	0.999936032	MOCOS	MOCOS	high	NA	NA	NA	"The gene maroon-like is referred to in FlyBase by the symbol Dmel\mal (CG1692, FBgn0002641). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:20429675..20433210. It has the cytological map location 19D1. Protein features are: Aminotransferase class V domain; MOSC, N-terminal beta barrel; Molybdenum cofactor sulfurase; Molybdenum cofactor sulfurase, C-terminal; Pyridoxal phosphate-dependent transferase; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; Pyridoxal phosphate-dependent transferase, subdomain 2; Pyruvate kinase-like, insert domain. Its molecular function is described by: Mo-molybdopterin cofactor sulfurase activity; molybdenum ion binding; pyridoxal phosphate binding. It is involved in the biological process described with: Mo-molybdopterin cofactor biosynthetic process; ommochrome biosynthetic process; molybdopterin cofactor metabolic process. 42 alleles are reported. The phenotypes of these alleles manifest in: pigment cell; Malpighian tubule. The phenotypic classes of alleles include: male fertile; fertile; stress response defective; phenotype; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0035358	CG14949	0.588173086	0.149173099	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14949 (FBgn0035358). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:2642184..2643424. It has the cytological map location 62E8. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, in adult male stages.  "
FBgn0031456	Tnpo-SR	0.588280384	0.155463081	0.999936032	NA	TNPO3	high	Maybe TF	transmembrane protein	NA	"The gene Transportin-Serine/Arginine rich is referred to in FlyBase by the symbol Dmel\Tnpo-SR (CG2848, FBgn0031456). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:2759924..2763889. It has the cytological map location 23A3-23A5. Protein features are: Armadillo-like helical; Armadillo-type fold; Exportin-1/Importin-beta-like; Importin-beta, N-terminal domain. Its molecular function is described by: protein binding; protein transporter activity; Ran GTPase binding; nuclear localization sequence binding. It is involved in the biological process described with: protein import into nucleus; regulation of mRNA splicing, via spliceosome; splicing factor protein import into nucleus. 6 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; ganglion mother cell; embryonic/larval neuroblast; mesothoracic tergum. The phenotypic classes of alleles include: increased mortality during development; phenotype; increased mortality; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0085265	CG34236	0.589163671	0.111565105	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG34236 (FBgn0085265). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:13604495..13605655. It has the cytological map location 50B5. Its molecular function is described by: . It is involved in the biological process described with: . One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0051414	Gba1b	0.589763882	0.100449158	0.999936032	NA	GBA	moderate	NA	NA	NA	"The gene Glucocerebrosidase 1b is referred to in FlyBase by the symbol Dmel\Gba1b (CG31414, FBgn0051414). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:23704804..23708512. It has the cytological map location 95A9-95A10. Protein features are: Glycoside hydrolase family 30; Glycoside hydrolase superfamily; Glycosyl hydrolase family 30, TIM-barrel domain; Glycosyl hydrolase family 30, beta sandwich domain. Its molecular function is described by: glucosylceramidase activity. It is involved in the biological process described with: glucosylceramide catabolic process; cellular response to unfolded protein; neuron cellular homeostasis; adult locomotory behavior; determination of adult lifespan; memory. 8 alleles are reported. The phenotypes of these alleles manifest in: ommatidium; mitochondrion; adult brain; rhabdomere; lysosome. The phenotypic classes of alleles include: oxidative stress response defective; viable; phenotype; stress response defective; behavior defective; sleep defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-18 embryonic stages, at stages throughout the larval period, during late pupal stages, in adult male stages.  "
FBgn0259247	laccase2	0.591131491	0.135299905	0.999936032	NA	HEPHL1;CP;HEPH	high;high;high	NA	NA	NA	"The gene laccase 2 is referred to in FlyBase by the symbol Dmel\laccase2 (CG42345, FBgn0259247). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (all unique). Gene sequence location is 2R:5413744..5456095. It has the cytological map location 41F1. Protein features are: Cupredoxin; Multicopper oxidase, copper-binding site; Multicopper oxidase, type 1; Multicopper oxidase, type 2; Multicopper oxidase, type 3; Multicopper oxidases, conserved site. Its molecular function is described by: iron ion transmembrane transporter activity; ferroxidase activity; copper ion binding. It is involved in the biological process described with: iron ion transport; chitin-based cuticle development; oxidation-reduction process; iron assimilation by reduction and transport. 14 alleles are reported. The phenotypes of these alleles manifest in: wing blade posterior compartment; mesothoracic tergum; trichogen cell. The phenotypic classes of alleles include: lethal - all die during embryonic stage; lethal; body color defective; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during late pupal stages.  "
FBgn0030574	CG9413	0.592817363	0.109213032	0.999936032	SLC7A9	SLC7A9;SLC7A7;SLC7A8;SLC7A6;SLC7A5;SLC7A10	high;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9413 (FBgn0030574). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is X:14584733..14602580. It has the cytological map location 12F1. Protein features are: Amino acid/polyamine transporter I. Its molecular function is described by: antiporter activity; L-amino acid transmembrane transporter activity; amino acid transmembrane transporter activity. It is involved in the biological process described with: amino acid transmembrane transport. 12 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during pupal stage; partially lethal; fertile; lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in adult male stages.  "
FBgn0250869	CG42240	0.593906725	0.125662364	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG42240 (FBgn0250869). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:6330842..6333028. It has the cytological map location 5F1-5F2. Its molecular function is described by: . It is involved in the biological process described with: . 8 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0035673	CG6602	0.595566815	0.14097858	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG6602 (FBgn0035673). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:6072139..6073539. It has the cytological map location 65A5. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. The phenotype of these alleles manifest in: male accessory gland secondary cell. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed in adult male stages.
FBgn0036575	CG5157	0.596497718	0.12247853	0.999936032	NA	CYB5B;CYB5A	moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5157 (FBgn0036575). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:16136487..16137879. It has the cytological map location 72D9. Protein features are: Cytochrome b5, heme-binding site; Cytochrome b5-like heme/steroid binding domain. Its molecular function is described by: heme binding. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0033096	Zip42C.1	0.597329623	0.14444012	0.999936032	NA	SLC39A3;SLC39A1;SLC39A2	high;moderate;moderate	NA	transmembrane protein	NA	"The gene Zinc/iron regulated transporter-related protein 42C.1 is referred to in FlyBase by the symbol Dmel\Zip42C.1 (CG9428, FBgn0033096). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:6716342..6717707. It has the cytological map location 42C6. Protein features are: Zinc/iron permease. Its molecular function is described by: zinc ion transmembrane transporter activity. It is involved in the biological process described with: detoxification of zinc ion; zinc II ion transmembrane import; zinc ion homeostasis; determination of adult lifespan; adult locomotory behavior. 7 alleles are reported. The phenotypes of these alleles manifest in: eye; melanotic mass. The phenotypic classes of alleles include: locomotor behavior defective; some die during larval stage; phenotype; short lived; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed in adult female stages.  "
FBgn0040388	boi	0.598148756	0.15178196	0.999936032	NA	CDON;BOC	high;high	NA	transmembrane protein	NA	"The gene brother of ihog is referred to in FlyBase by the symbol Dmel\boi (CG32796, FBgn0040388). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is X:2444167..2470043. It has the cytological map location 3A3. Protein features are: Fibronectin type III; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold; Interference hedgehog. Its molecular function is described by: hedgehog family protein binding. It is involved in the biological process described with: wing disc pattern formation; cuticle pattern formation; compound eye photoreceptor cell differentiation; compound eye development; smoothened signaling pathway; regulation of smoothened signaling pathway; Notch signaling pathway; positive regulation of cell proliferation. 27 alleles are reported. The phenotypes of these alleles manifest in: interfollicle cell; wing blade; follicle cell; wing vein; follicle stem cell. The phenotypic classes of alleles include: fertile; viable; visible; hyperplasia. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, during early pupal stages.  "
FBgn0031420	Atxn7	0.599955993	0.153448827	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Ataxin 7 is referred to in FlyBase by the symbol Dmel\Atxn7 (CG9866, FBgn0031420). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2L:2375841..2380506. It has the cytological map location 22E1. Its molecular function is described by: . It is involved in the biological process described with: positive regulation of histone H2B ubiquitination; SAGA complex assembly. 5 alleles are reported. The phenotypes of these alleles manifest in: adult brain; retina; eye. The phenotypic classes of alleles include: short lived; majority die during prepupal stage; neuroanatomy defective; locomotor behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages.  "
FBgn0267617	CR45955	0.60093403	0.144612461	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45955 (FBgn0267617). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3L:21636643..21637314. It has the cytological map location 78E1. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0267041	CR45485	0.601311056	0.127201548	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45485 (FBgn0267041). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is X:16307032..16308687. It has the cytological map location 14B9. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0003888	betaTub60D	0.603148914	0.109108589	0.999936032	TUBB4A	TUBB6;TUBB4B;TUBB4A;TUBB3;TUBB;TUBB1;TUBB2A;TUBB2B;TUBB8	high;moderate;moderate;moderate;moderate;moderate;low;low;moderate	NA	NA	NA	"The gene ‘_-Tubulin at 60D is referred to in FlyBase by the symbol Dmel\‘_Tub60D (CG3401, FBgn0003888). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:24305881..24313099. It has the cytological map location 60C6. Protein features are: Beta tubulin; Beta tubulin, autoregulation binding site; Tubulin; Tubulin, conserved site; Tubulin/FtsZ, 2-layer sandwich domain; Tubulin/FtsZ, C-terminal; Tubulin/FtsZ, GTPase domain. Its molecular function is described by: GTPase activity; structural constituent of cytoskeleton; GTP binding. It is involved in the biological process described with: axon guidance; heart development; response to light stimulus; axonogenesis; microtubule-based process; larval behavior. 25 alleles are reported. The phenotypes of these alleles manifest in: sense organ; intracellular part; intracellular non-membrane-bounded organelle; somatic precursor cell; cell component; dorsal mesothorax; single-organism cellular process; non-membrane-bounded organelle; neuromuscular junction; cellular process; tagmatic subdivision of integument. The phenotypic classes of alleles include: phenotype; increased mortality; lethal; sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 06-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0023407	B4	0.603313129	0.133546938	0.999936032	NA	NA	NA	NA	NA	NA	"The gene B4 is referred to in FlyBase by the symbol Dmel\B4 (CG9239, FBgn0023407). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:13500624..13549328. It has the cytological map location 34C3-34C4. Protein features are: CABIT domain. Its molecular function is unknown. It is involved in the biological process described with: imaginal disc development; circadian rhythm. 51 alleles are reported. The phenotypes of these alleles manifest in: eye; eye photoreceptor cell; trichogen cell; imaginal disc; wing vein; wing; ommatidium. The phenotypic classes of alleles include: lethal - all die before end of P-stage; visible; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, during early pupal stages, in adult female stages.  "
FBgn0027581	CG6191	0.603739564	0.116709741	0.999936032	NA	CABLES1;CABLES2	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6191 (FBgn0027581). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 2R:13580313..13593339. It has the cytological map location 50B3-50B4. Protein features are: CDK5 and ABL1 enzyme substrate 1/2; Cyclin, N-terminal; Cyclin-like; WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. It is involved in the biological process described with: phagocytosis; regulation of imaginal disc-derived wing size; regulation of cell cycle. 13 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: size defective; viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed during early pupal stages.  "
FBgn0262854	CG43218	0.60446009	0.144118093	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG43218 (FBgn0262854). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:21258020..21258758. It has the cytological map location 78C3. Protein features are: Chitin binding domain. Its molecular function is described by: chitin binding. It is involved in the biological process described with: chitin metabolic process. No alleles are reported.
FBgn0005390	fs(1)M3	0.605212438	0.100091342	0.999936032	NA	NA	NA	NA	NA	NA	"The gene female sterile (1) M3 is referred to in FlyBase by the symbol Dmel\fs(1)M3 (CG4790, FBgn0005390). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:5958207..5964247. It has the cytological map location 5D1. Protein features are: WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. It is involved in the biological process described with: chorion-containing eggshell formation; vitelline membrane formation involved in chorion-containing eggshell formation; terminal region determination. 19 alleles are reported. The phenotypes of these alleles manifest in: multicellular structure; acellular anatomical structure; vitelline membrane; ocular segment; abdominal segment 10; terminalia; embryonic/larval digestive system; cephalic furrow; adult segment; embryonic abdominal segment. The phenotypic classes of alleles include: viable; lethal - all die before end of embryonic stage; lethal; female sterile; some die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed in adult female stages.  "
FBgn0027558	pgant3	0.60713474	0.126709369	0.999936032	NA	GALNT1;POC1B-GALNT4;GALNTL5;GALNT6;GALNT12;GALNT5;GALNT13;GALNT11;GALNT7;GALNT3;GALNTL6;GALNT4;GALNT10	moderate;low;low;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene polypeptide GalNAc transferase 3 is referred to in FlyBase by the symbol Dmel\pgant3 (CG4445, FBgn0027558). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:7057654..7061732. It has the cytological map location 42E7. Protein features are: Glycosyltransferase 2-like; Nucleotide-diphospho-sugar transferases; Ricin B, lectin domain. Its molecular function is described by: acetylgalactosaminyltransferase activity; transferase activity, transferring glycosyl groups; polypeptide N-acetylgalactosaminyltransferase activity. It is involved in the biological process described with: O-glycan processing; protein O-linked glycosylation; oligosaccharide biosynthetic process; cell-substrate adhesion; regulation of cell adhesion mediated by integrin; extracellular matrix constituent secretion. 14 alleles are reported. The phenotypes of these alleles manifest in: wing blade; wing disc. The phenotypic classes of alleles include: partially lethal - majority die; visible; viable; lethal; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 12-18 embryonic stages.  "
FBgn0034756	Cyp6d2	0.607248786	0.103899336	0.999936032	NA	TBXAS1;CYP3A43;CYP3A4;CYP3A5;CYP3A7-CYP3A51P	moderate;low;low;low;low	NA	NA	NA	"The gene Cyp6d2 is referred to in FlyBase by the symbol Dmel\Cyp6d2 (CG4373, FBgn0034756). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:22652573..22654530. It has the cytological map location 58F4. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Its molecular function is described by: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; iron ion binding; heme binding; oxidoreductase activity. It is involved in the biological process described with: response to camptothecin; oxidation-reduction process. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: chemical sensitive; partially lethal; some die during embryonic stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed during late larval stages, during early pupal stages, in stages of adults of both sexes.  "
FBgn0052115	CG32115	0.610092269	0.118310903	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32115 (FBgn0052115). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:12912027..12913646. It has the cytological map location 69F1. Protein features are: Leucine-rich repeat domain, L domain-like. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0024187	syd	0.61098033	0.124244027	0.999936032	NA	SPAG9;MAPK8IP3	high;high	NA	transmembrane protein	NA	"The gene sunday driver is referred to in FlyBase by the symbol Dmel\syd (CG8110, FBgn0024187). It is a protein_coding_gene from Drosophila melanogaster. It has 11 annotated transcripts and 11 polypeptides (10 unique). Gene sequence location is 3L:7916650..7936120. It has the cytological map location 66A20. Protein features are: JNK-interacting protein, leucine zipper II; JNK/Rab-associated protein-1, N-terminal; Quinoprotein amine dehydrogenase, beta chain-like; RH1 domain; RH2 domain; Tetratricopeptide-like helical domain; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: MAP-kinase scaffold activity; JUN kinase binding; receptor signaling complex scaffold activity; kinesin binding. It is involved in the biological process described with: vesicle-mediated transport; axo-dendritic transport; regulation of JNK cascade; activation of JUN kinase activity. 12 alleles are reported. The phenotypes of these alleles manifest in: abdominal segmental nerve; larva; NMJ bouton; synaptic vesicle. The phenotypic classes of alleles include: phenotype; increased mortality during development; viable; lethal - all die before end of larval stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, during early pupal stages, in adult male stages.  "
FBgn0033696	Cyp6g2	0.612276168	0.125344017	0.999936032	NA	TBXAS1;CYP3A43;CYP3A4;CYP3A5;CYP3A7-CYP3A51P	moderate;low;low;low;low	NA	transmembrane protein	NA	"The gene Cyp6g2 is referred to in FlyBase by the symbol Dmel\Cyp6g2 (CG8859, FBgn0033696). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:12188338..12190377. It has the cytological map location 48E7. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group IV; Cytochrome P450, conserved site. Its molecular function is described by: oxidoreductase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; iron ion binding; monooxygenase activity; heme binding. It is involved in the biological process described with: response to insecticide; oxidation-reduction process. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: chemical resistant; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed in adult male stages.  "
FBgn0039269	veli	0.613001619	0.118180224	0.999936032	NA	LIN7B;LIN7C;LIN7A;PDZD11	high;moderate;moderate;moderate	NA	NA	NA	"The gene veli is referred to in FlyBase by the symbol Dmel\veli (CG7662, FBgn0039269). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:25064418..25065591. It has the cytological map location 96B19. Protein features are: L27 domain; L27 domain, C-terminal; PDZ domain; Protein lin-7. Its molecular function is unknown. It is involved in the biological process described with: establishment or maintenance of cell polarity; border follicle cell migration; regulation of synaptic growth at neuromuscular junction; protein localization to basolateral plasma membrane; maintenance of epithelial cell apical/basal polarity; neurotransmitter secretion. 13 alleles are reported. The phenotypes of these alleles manifest in: neuromuscular junction; chaeta; border follicle cell; eye photoreceptor cell; trichogen cell. The phenotypic classes of alleles include: neuroanatomy defective; partially lethal - majority die; some die during pupal stage; fertile; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0033222	CG12824	0.616028544	0.096294334	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12824 (FBgn0033222). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:7790368..7791170. It has the cytological map location 43E16. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0024698	Cpsf160	0.616628166	0.142163101	0.999936032	NA	CPSF1;MIR6849	high;moderate	NA	NA	NA	"The gene Cleavage and polyadenylation specificity factor 160 is referred to in FlyBase by the symbol Dmel\Cpsf160 (CG10110, FBgn0024698). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:14497347..14503488. It has the cytological map location 51A4. Protein features are: Cleavage/polyadenylation specificity factor, A subunit, C-terminal; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: myosin binding; mRNA 3'-UTR binding; mRNA binding. It is involved in the biological process described with: mRNA cleavage; mRNA polyadenylation. 13 alleles are reported. The phenotypes of these alleles manifest in: embryonic/first instar larval cuticle; embryonic/larval neuroblast; ganglion mother cell; hypostomal sclerite. The phenotypic classes of alleles include: lethal; increased mortality; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, in adult female stages.  "
FBgn0040087	p115	0.618951926	0.110945537	0.999936032	NA	USO1	high	NA	NA	NA	"The gene p115 is referred to in FlyBase by the symbol Dmel\p115 (CG1422, FBgn0040087). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:7894031..7896991. It has the cytological map location 7C2. Protein features are: Armadillo; Armadillo-like helical; Armadillo-type fold; Uso1/p115-like vesicle tethering protein, C-terminal; Vesicle tethering protein Uso1/P115-like , head domain. Its molecular function is described by: protein transporter activity. It is involved in the biological process described with: Golgi vesicle docking; transcytosis; intracellular protein transport; regulation of cell cycle; ER to Golgi vesicle-mediated transport; vesicle fusion with Golgi apparatus; Golgi organization; membrane fusion. 8 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: partially lethal - majority die; body color defective; viable; flight defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.  "
FBgn0052590	CG32590	0.620705939	0.136206721	0.999936032	MEF2BNB	BORCS8	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32590 (FBgn0052590). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:14838352..14839106. It has the cytological map location 12F5. Protein features are: BLOC-1-related complex subunit 8. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of low expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0027560	Tps1	0.621176669	0.12182329	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Trehalose-6-phosphate synthase 1 is referred to in FlyBase by the symbol Dmel\Tps1 (CG4104, FBgn0027560). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:4388327..4392778. It has the cytological map location 24E4-24E5. Protein features are: Glycosyl transferase, family 20; HAD-like domain; HAD-superfamily hydrolase, subfamily IIB; Trehalose-phosphatase. Its molecular function is described by: trehalose-phosphatase activity. It is involved in the biological process described with: photoreceptor cell maintenance; trehalose biosynthetic process; trehalose metabolism in response to stress. 22 alleles are reported. The phenotypes of these alleles manifest in: retina; ommatidium; eye photoreceptor cell; eye; embryonic/larval hemolymph; rhabdomere of eye photoreceptor cell. The phenotypic classes of alleles include: visible; lethal - all die before end of prepupal stage; phenotype; stress response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0030955	CG6891	0.62236311	0.09111055	0.999936032	COTL1	COTL1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6891 (FBgn0030955). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:18775228..18781345. It has the cytological map location 17D4-17D5. Protein features are: ADF-H/Gelsolin-like domain; Actin-depolymerising factor homology domain; Coactosin-like protein. Its molecular function is described by: actin binding. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 06-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0019928	Ser8	0.62276726	0.087582253	0.999936032	NA	PRSS36;PRSS53;GZMM;PRSS1;PRSS3	low;low;low;low;low	NA	transmembrane protein	NA	"The gene Ser8 is referred to in FlyBase by the symbol Dmel\Ser8 (CG4812, FBgn0019928). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:13434207..13435045. It has the cytological map location 50A8. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity; serine-type peptidase activity. It is involved in the biological process described with: proteolysis. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable; lethal - all die during embryonic stage; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed in adults stages of both sexes.  "
FBgn0040959	Peritrophin-15a	0.622934926	0.086603903	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Peritrophin-15a is referred to in FlyBase by the symbol Dmel\Peritrophin-15a (CG17814, FBgn0040959). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:8395665..8396096. It has the cytological map location 29C1. Protein features are: Chitin binding domain. Its molecular function is described by: chitin binding. It is involved in the biological process described with: chitin metabolic process. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period.  "
FBgn0262869	Gfrl	0.624381664	0.084182433	0.999936032	NA	GFRAL;GFRA1;GFRA2;GFRA4;GFRA3	high;moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene Glial cell line-derived neurotrophic family receptor-like is referred to in FlyBase by the symbol Dmel\Gfrl (CG43224, FBgn0262869). It is a protein_coding_gene from Drosophila melanogaster. It has 10 annotated transcripts and 10 polypeptides (8 unique). Gene sequence location is 3R:20378458..20484588. It has the cytological map location 92E5-92E6. Protein features are: GDNF/GAS1. Its molecular function is described by: cell adhesion molecule binding. The biological processes in which it is involved are not known. 22 alleles are reported. The phenotypes of these alleles manifest in: egg; mesothoracic tergum; trichogen cell; dorsal appendage. The phenotypic classes of alleles include: visible; increased mortality during development; phenotype; increased mortality."
FBgn0063667	CG32335	0.625000261	0.135447901	0.999936032	NA	C11orf54	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32335 (FBgn0063667). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:1201871..1203036. It has the cytological map location 61F3. Protein features are: Domain of unknown function DUF1907. Its molecular function is described by: zinc ion binding; hydrolase activity, acting on ester bonds. It is involved in the biological process described with: . 2 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: some die during pupal stage; partially lethal - majority die; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 06-18 hour embryonic stages, during early larval stages.  "
FBgn0045842	yuri	0.626086714	0.124662306	0.999936032	NA	NA	NA	NA	NA	NA	"The gene yuri gagarin is referred to in FlyBase by the symbol Dmel\yuri (CG31732, FBgn0045842). It is a protein_coding_gene from Drosophila melanogaster. It has 8 annotated transcripts and 8 polypeptides (6 unique). Gene sequence location is 2L:15257267..15264692. It has the cytological map location 35C5. Protein features are: Yuri gagarin. Its molecular function is unknown. It is involved in the biological process described with: gravitaxis; ciliary basal body organization; sperm individualization. 16 alleles are reported. The phenotypes of these alleles manifest in: spermatid cyst; ciliary basal body; investment cone; filamentous actin; spermatozoon; spermatid. The phenotypic classes of alleles include: gravitaxis defective; auditory perception defective; sterile; viable; flight defective; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during early pupal stages.  "
FBgn0085205	CG34176	0.626728071	0.085934065	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG34176 (FBgn0085205). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:4004080..4004480. It has the cytological map location 24D3. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, in adult male stages.  "
FBgn0038542	TyrR	0.627883533	0.120737951	0.999936032	NA	DRD5;DRD1;ADRA1D;HTR4;HRH2;HRH1;DRD2;DRD3;DRD4	low;low;low;low;low;low;low;low;low	NA	transmembrane protein	GPCR	"The gene Tyramine receptor is referred to in FlyBase by the symbol Dmel\TyrR (CG7431, FBgn0038542). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 3R:17750129..17763188. It has the cytological map location 90C2-90C3. Protein features are: G protein-coupled receptor, rhodopsin-like; GPCR, rhodopsin-like, 7TM. Its molecular function is described by: tyramine receptor activity; G-protein coupled amine receptor activity. It is involved in the biological process described with: phospholipase C-activating dopamine receptor signaling pathway; tyramine signaling pathway; learning; positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway; adenylate cyclase-activating dopamine receptor signaling pathway; G-protein coupled receptor signaling pathway; cellular response to amine stimulus; octopamine or tyramine signaling pathway. 14 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: courtship behavior defective; visible; viable; flight defective; fertile; short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 06-12 and 18-24 hour embryonic stages, during late larval stages.  "
FBgn0016034	mael	0.628562534	0.104085964	0.999936032	MAEL	MAEL	high	NA	NA	NA	"The gene maelstrom is referred to in FlyBase by the symbol Dmel\mael (CG11254, FBgn0016034). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3L:22721203..22726234. It has the cytological map location 80A1. Protein features are: High mobility group box domain; Maelstrom domain. Its molecular function is described by: sequence-specific DNA binding; transcription regulatory region DNA binding. It is involved in the biological process described with 22 unique terms, many of which group under: cytoskeleton organization; regulation of intracellular mRNA localization; protein localization; germ-line stem cell population maintenance; heterocycle metabolic process; spermatogenesis; regulation of multicellular organismal development; nucleobase-containing compound biosynthetic process; organelle fission; epithelial cell development; male meiotic nuclear division; oocyte fate commitment. 25 alleles are reported. The phenotypes of these alleles manifest in: karyosome; chorion; material anatomical entity; somatic cell of ovary; external encapsulating structure; germinal proliferation center; dorsal appendage; portion of tissue; cell part; cell component; cystoblast. The phenotypic classes of alleles include: female semi-sterile; lethal - all die before end of embryonic stage; viable; female sterile; wild-type; some die during embryonic stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0032456	MRP	0.628888558	0.089756588	0.999936032	ABCC3	ABCC3;ABCC1;ABCC6;ABCC2;ABCC8;ABCC9;ABCC4;ABCC10;ABCC12;ABCC11;ABCC5	high;moderate;moderate;moderate;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene Multidrug-Resistance like Protein 1 is referred to in FlyBase by the symbol Dmel\MRP (CG6214, FBgn0032456). It is a protein_coding_gene from Drosophila melanogaster. It has 18 annotated transcripts and 18 polypeptides (17 unique). Gene sequence location is 2L:12719045..12766546. It has the cytological map location 33F3-33F5. Protein features are: AAA+ ATPase domain; ABC transporter type 1, transmembrane domain; ABC transporter, conserved site; ABC transporter-like; Canalicular multispecific organic anion transporter 1; Multi drug resistance-associated protein; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: ATP binding; ATPase activity, coupled to movement of substances; organic anion transmembrane transporter activity; ATPase activity, coupled to transmembrane movement of substances. It is involved in the biological process described with: transmembrane transport; renal tubular secretion; response to toxic substance. 12 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed within 00-06 and 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0030929	CG15043	0.629028878	0.083274139	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG15043 (FBgn0030929). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:18493193..18494168. It has the cytological map location 17B5. Protein features are: Transcription activator MBF2. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during late larval stages.
FBgn0259170	alpha-Man-Ia	0.631129608	0.130979853	0.999936032	NA	MAN1A2;MAN1A1;MAN1C1	high;moderate;moderate	NA	transmembrane protein	NA	"The gene ‘±-Mannosidase class I a is referred to in FlyBase by the symbol Dmel\‘±-Man-Ia (CG42275, FBgn0259170). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (3 unique). Gene sequence location is X:10266792..10325958. It has the cytological map location 9B6-9B7. Protein features are: Glycoside hydrolase family 47. Its molecular function is described by: calcium ion binding; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. It is involved in the biological process described with: N-glycan processing; response to anesthetic; encapsulation of foreign target; determination of adult lifespan. 44 alleles are reported. The phenotypes of these alleles manifest in: Z disc; trichogen cell; peripheral nervous system; myofibril; sarcomere; interommatidial bristle; ommatidium. The phenotypic classes of alleles include: flight defective; phenotype; viable; visible; chemical sensitive. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 and 12-18 hour embryonic stages.  "
FBgn0037936	CG6908	0.632071648	0.089968081	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG6908 (FBgn0037936). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:11688381..11690051. It has the cytological map location 86E16. Protein features are: CHK kinase-like; Protein kinase-like domain; Protein of unknown function DUF227. Its molecular function is unknown. It is involved in the biological process described with: copper ion homeostasis. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages.
FBgn0031004	CG7992	0.633204062	0.08594145	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG7992 (FBgn0031004). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:19245158..19247250. It has the cytological map location 18B4-18B5. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages.
FBgn0038658	CG14292	0.635094228	0.079614649	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14292 (FBgn0038658). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:18904933..18905655. It has the cytological map location 91D4. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0266859	CR45320	0.637912404	0.125393066	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45320 (FBgn0266859). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2R:7451670..7452365. It has the cytological map location 43C2. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0031602	CG15431	0.640436335	0.126896593	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15431 (FBgn0031602). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:4403992..4441282. It has the cytological map location 24F1. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: viable; body color defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.  "
FBgn0032633	Lrch	0.641005571	0.108300462	0.999936032	NA	LRCH3;LRCH2;LRCH1;LRCH4	high;high;moderate;moderate	NA	transmembrane protein	NA	"The gene Leucine-rich-repeats and calponin homology domain protein is referred to in FlyBase by the symbol Dmel\Lrch (CG6860, FBgn0032633). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 2L:17367511..17384115. It has the cytological map location 36C7. Protein features are: Calponin homology domain; Cyclic nucleotide-binding domain; Leucine-rich repeat; Leucine-rich repeat domain, L domain-like; Leucine-rich repeat, typical subtype. Its molecular function is unknown. It is involved in the biological process described with: signal transduction. 20 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during early pupal stages.  "
FBgn0050421	Usp15-31	0.641228691	0.116692444	0.999936032	NA	USP31;USP43;USP11	high;moderate;moderate	NA	NA	NA	"The gene Ubiquitin specific protease 15/31 is referred to in FlyBase by the symbol Dmel\Usp15-31 (CG30421, FBgn0050421). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2R:24743749..24756976. It has the cytological map location 60D16-60E1. Protein features are: Peptidase C19, ubiquitin carboxyl-terminal hydrolase; Ubiquitin specific protease domain; Ubiquitin specific protease, conserved site. Its molecular function is described by: thiol-dependent ubiquitin-specific protease activity. It is involved in the biological process described with: ubiquitin-dependent protein catabolic process; protein deubiquitination. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; locomotor behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0013680	mt:ND2	0.641684755	0.080155873	0.999936032	NA	ND2	high	NA	transmembrane protein	NA	"The gene mitochondrial NADH-ubiquinone oxidoreductase chain 2 is referred to in FlyBase by the symbol Dmel\mt:ND2 (CG34063, FBgn0013680). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is mitochondrion_genome:240..1265. Protein features are: NADH dehydrogenase subunit 2, C-terminal; NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit; NADH:ubiquinone oxidoreductase, chain 2. Its molecular function is described by: NADH dehydrogenase (ubiquinone) activity. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: flight defective; short lived; stress response defective; bang sensitive; heat stress response defective; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very low expression to a trough of no expression detected.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, during early pupal stages.  "
FBgn0030600	hiw	0.641773831	0.096317484	0.999936032	NA	MYCBP2	high	NA	NA	NA	"The gene highwire is referred to in FlyBase by the symbol Dmel\hiw (CG32592, FBgn0030600). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:15010137..15063429. It has the cytological map location 13A5-13A8. Protein features are: APC10/DOC domain; Filamin/ABP280 repeat-like; Galactose-binding domain-like; Immunoglobulin E-set; Immunoglobulin-like fold; PHR; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; Regulator of chromosome condensation, RCC1; Zinc finger, RING-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is described by: ubiquitin-protein transferase activity; protein binding; zinc ion binding. It is involved in the biological process described with 14 unique terms, many of which group under: single-organism behavior; cellular catabolic process; sensory perception; adult locomotory behavior; locomotion; response to wounding; negative regulation of metabolic process; autophagy; detection of abiotic stimulus; walking behavior. 78 alleles are reported. The phenotypes of these alleles manifest in: synapse; cell; neuron projection; synapse; nerve; neuromuscular junction; axon part; endomembrane system; giant fiber neuron; synapse part. The phenotypic classes of alleles include: stress response defective; phenotype; neurophysiology defective; behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 06-24 hour embryonic stages, at stages throughout the pupal period, in adult male stages.  "
FBgn0028387	chm	0.642943587	0.126070343	0.999936032	NA	KAT7;KAT6B;KAT6A;KAT5;KAT8	high;low;low;low;low	DNA-binding with transcription factor activity(zf-C2HC)	NA	NA	"The gene chameau is referred to in FlyBase by the symbol Dmel\chm (CG5229, FBgn0028387). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:7412417..7422736. It has the cytological map location 27F3-27F4. Protein features are: Acyl-CoA N-acyltransferase; Histone acetyltransferase domain, MYST-type; Zinc finger, C2HC-type. Its molecular function is described by: histone acetyltransferase activity; H3 histone acetyltransferase activity; zinc ion binding; H4 histone acetyltransferase activity; transcription factor binding; transcription coactivator activity; transcription factor activity, sequence-specific DNA binding. It is involved in the biological process described with 15 unique terms, many of which group under: neuron differentiation; negative regulation of developmental process; neuron projection morphogenesis; dorsal/ventral pattern formation, imaginal disc; cell fate determination; post-embryonic animal organ development; carbohydrate metabolic process; negative regulation of cell fate commitment; instar larval or pupal morphogenesis; gene silencing. 22 alleles are reported. The phenotype of these alleles manifest in: adult thorax. The phenotypic classes of alleles include: suppressor of variegation; some die during pupal stage; lethal - all die before end of pupal stage; wild-type; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0264603	CR43952	0.644005225	0.125270819	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR43952 (FBgn0264603). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3L:6036490..6036915. It has the cytological map location 65A3. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported.
FBgn0263241	Mocs1	0.645920562	0.100448349	0.999936032	NA	MOCS1	high	NA	NA	NA	"The gene Molybdenum cofactor synthesis 1 is referred to in FlyBase by the symbol Dmel\Mocs1 (CG33048, FBgn0263241). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:11070526..11073348. It has the cytological map location 68A3-68A5. Protein features are: Aldolase-type TIM barrel; Elongator protein 3/MiaB/NifB; Main SPASM domain-containing; MoaA/nifB/pqqE, iron-sulphur binding, conserved site; Molybdenum cofactor biosynthesis C; Molybdenum cofactor biosynthesis protein A; Molybdenum cofactor synthesis C-terminal; Molybdopterin cofactor biosynthesis C (MoaC) domain; Radical SAM. Its molecular function is described by: metal ion binding; 4 iron, 4 sulfur cluster binding; catalytic activity. It is involved in the biological process described with: Mo-molybdopterin cofactor biosynthetic process. 27 alleles are reported. The phenotype of these alleles manifest in: pigment cell. The phenotypic classes of alleles include: eye color defective; viable; lethal."
FBgn0038180	Cht5	0.648143295	0.122776249	0.999936032	NA	CHIA;OVGP1;CHI3L2;CHI3L1;CHIT1	moderate;moderate;moderate;moderate;low	NA	NA	NA	"The gene Chitinase 5 is referred to in FlyBase by the symbol Dmel\Cht5 (CG9307, FBgn0038180). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:13767549..13770732. It has the cytological map location 87F13. Protein features are: Chitin binding domain; Chitinase II; Chitinase insertion domain; Glycoside hydrolase family 18, catalytic domain; Glycoside hydrolase superfamily; Glycoside hydrolase, chitinase active site. Its molecular function is described by: chitin binding; chitinase activity. It is involved in the biological process described with: ecdysis, chitin-based cuticle; chitin-based cuticle development; carbohydrate metabolic process; wound healing; chitin catabolic process. 6 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval cuticle; pupal cuticle; wing. The phenotypic classes of alleles include: fertile; increased mortality; some die during P-stage; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the pupal period.  "
FBgn0003512	Sry-delta	0.650074904	0.098612362	0.999936032	NA	ZNF200;ZNF449;GZF1	low;low;low	DNA-binding with transcription factor activity(zf-C2H2)	NA	NA	"The gene Serendipity ‘Ç is referred to in FlyBase by the symbol Dmel\Sry-‘Ç (CG17958, FBgn0003512). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:30043341..30044886. It has the cytological map location 99D3. Protein features are: Zinc finger C2H2-type. Its molecular function is described by: DNA binding; transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding. It is involved in the biological process described with: bicoid mRNA localization; anterior/posterior axis specification, embryo; positive regulation of transcription from RNA polymerase II promoter; multicellular organism reproduction; oogenesis. 23 alleles are reported. The phenotypes of these alleles manifest in: wing; gonad; spermatozoon; embryonic/first instar larval cuticle; cephalopharyngeal skeleton; testis; telson. The phenotypic classes of alleles include: wild-type; lethal; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0039528	dsd	0.651474889	0.085578403	0.999936032	ATRN	ATRN;ATRNL1	high;moderate	NA	transmembrane protein	NA	"The gene distracted is referred to in FlyBase by the symbol Dmel\dsd (CG5634, FBgn0039528). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:27597563..27607396. It has the cytological map location 98A10. Protein features are: CUB domain; EGF-like domain; EGF-like, conserved site; Galactose oxidase, beta-propeller; Kelch-type beta propeller; Laminin EGF domain; PSI domain. Its molecular function is described by: . It is involved in the biological process described with: synaptic target recognition. 12 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 and 12-18 hour embryonic stages, during late pupal stages, in adult female stages.  "
FBgn0065098	RNaseMRP:RNA	0.652674902	0.118185477	0.999936032	NA	ABCC1	low	NA	NA	NA	"The gene Ribonuclease MRP RNA is referred to in FlyBase by the symbol Dmel\RNaseMRP:RNA (CR33682, FBgn0065098). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3R:23730048..23730429. It has the cytological map location 95B1. Its molecular function is unknown. It is involved in the biological process described with: endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA). 2 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during second instar larval stage; lethal - all die before end of second instar larval stage; developmental rate defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during early pupal stages.  CAVEAT: These RNA-Seq temporal profiles depend upon RNA-Seq reads that are uniquely placed in the genome.  For this reason, genes such as histones, Stellates and many classes of RNA genes that are present in multiple exact or near exact copies in the genome, expression levels may be reported as much lower than their true values."
FBgn0052024	CG32024	0.654428882	0.100710768	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG32024 (FBgn0052024). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:8807601..8808407. It has the cytological map location 66D15. Protein features are: Chitin binding domain. Its molecular function is described by: chitin binding. It is involved in the biological process described with: chitin metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during late pupal stages.
FBgn0000303	ChAT	0.655384158	0.106707236	0.999936032	NA	CHAT;CRAT	high;low	NA	NA	NA	"The gene Choline acetyltransferase is referred to in FlyBase by the symbol Dmel\ChAT (CG12345, FBgn0000303). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:18705501..18732344. It has the cytological map location 91C1-91C5. Protein features are: Acyltransferase ChoActase/COT/CPT. Its molecular function is described by: choline O-acetyltransferase activity. It is involved in the biological process described with: neuromuscular synaptic transmission; acetylcholine biosynthetic process. 47 alleles are reported. The phenotypes of these alleles manifest in: axon; motor neuron; dorsal medial muscle; eye photoreceptor cell; lamina anlage; aCC neuron; RP2 motor neuron; dendrite. The phenotypic classes of alleles include: phototaxis defective; behavior defective; fertile; lethal - all die before end of prepupal stage; phenotype; mating defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0040297	Nhe2	0.65594901	0.085066011	0.999936032	NA	SLC9A5;SLC9A3;SLC9A2;SLC9A1;SLC9A4	high;high;moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene Na<sup>+</sup>/H<sup>+</sup> hydrogen exchanger 2 is referred to in FlyBase by the symbol Dmel\Nhe2 (CG9256, FBgn0040297). It is a protein_coding_gene from Drosophila melanogaster. It has 12 annotated transcripts and 12 polypeptides (11 unique). Gene sequence location is 2L:21104568..21134255. It has the cytological map location 39A2-39A3. Protein features are: Cation/H+ exchanger; Cation/H+ exchanger, CPA1 family; Na+/H+ exchanger. Its molecular function is described by: potassium:proton antiporter activity; sodium:proton antiporter activity. It is involved in the biological process described with: potassium ion transmembrane transport; sodium ion import across plasma membrane; compound eye morphogenesis; cellular ion homeostasis; regulation of intracellular pH; regulation of cellular pH. 37 alleles are reported. The phenotypes of these alleles manifest in: mechanosensory sensory organ; embryonic/larval adipose system; thorax; embryonic/larval digestive system; eye disc; secondary pigment cell; microchaeta; embryonic/larval fat body; digestive system; fat body; primary pigment cell. The phenotypic classes of alleles include: cell number defective; some die during larval stage; increased mortality; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 and 18-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in adult male stages.  "
FBgn0263220	Hk	0.656170775	0.112080921	0.999936032	NA	KCNAB1;KCNAB2;KCNAB3	high;high;moderate	NA	transmembrane protein	NA	"The gene Hyperkinetic is referred to in FlyBase by the symbol Dmel\Hk (CG43388, FBgn0263220). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (8 unique). Gene sequence location is X:10233347..10263485. It has the cytological map location 9B5. Protein features are: NADP-dependent oxidoreductase domain; Potassium channel, voltage-dependent, beta subunit, KCNAB; Potassium channel, voltage-dependent, beta subunit, KCNAB-related; WD40/YVTN repeat-like-containing domain. Its molecular function is described by: voltage-gated potassium channel activity; potassium channel regulator activity. It is involved in the biological process described with: positive regulation of circadian sleep/wake cycle, sleep; potassium ion transport; flight behavior; circadian sleep/wake cycle, sleep; protein oligomerization. 20 alleles are reported. The phenotype of these alleles manifest in: leg. The phenotypic classes of alleles include: viable; phenotype; increased mortality; fertile; behavior defective."
FBgn0038734	CG11453	0.65665288	0.083497086	0.999936032	NA	ACSBG1;AACS;ACSF3	low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11453 (FBgn0038734). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:19783522..19785519. It has the cytological map location 92B2. Protein features are: AMP-binding enzyme, C-terminal domain; AMP-binding, conserved site; AMP-dependent synthetase/ligase. Its molecular function is described by: catalytic activity. It is involved in the biological process described with: metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0085195	CG34166	0.65765438	0.102598209	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG34166 (FBgn0085195). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (1 unique). Gene sequence location is 2L:14743193..14743879. It has the cytological map location 35B5. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. The phenotypes of these alleles manifest in: segment of leg; leg. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of extremely low expression.  Peak expression observed during late larval stages.
FBgn0259715	CG42369	0.664945755	0.112782329	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG42369 (FBgn0259715). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:6395853..6397249. It has the cytological map location 26D1. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages, in adult male stages.  "
FBgn0034288	CG5084	0.668372811	0.107984229	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5084 (FBgn0034288). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:18018665..18020211. It has the cytological map location 55B1. Protein features are: Protein of unknown function DUF725. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period.  "
FBgn0036716	CG13728	0.669558475	0.104257716	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG13728 (FBgn0036716). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:17380026..17382728. It has the cytological map location 74A6. Protein features are: WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed during late pupal stages.
FBgn0030774	spheroide	0.671417724	0.0685851	0.999936032	NA	PRSS38	low	NA	NA	NA	"The gene spheroide is referred to in FlyBase by the symbol Dmel\spheroide (CG9675, FBgn0030774). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:16700446..16701972. It has the cytological map location 15A1-15A2. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain. Its molecular function is unknown. It is involved in the biological process described with: positive regulation of Toll signaling pathway; defense response to fungus; proteolysis; innate immune response; defense response to Gram-positive bacterium. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: immune response defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0261244	inaE	0.671469655	0.108546518	0.999936032	NA	DAGLA;DAGLB	high;moderate	NA	transmembrane protein	NA	"The gene inactivation no afterpotential E is referred to in FlyBase by the symbol Dmel\inaE (CG33174, FBgn0261244). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (all unique). Gene sequence location is X:13783714..13811493. It has the cytological map location 12C4-12C5. Protein features are: Alpha/Beta hydrolase fold; Fungal lipase-like domain. Its molecular function is described by: lipoprotein lipase activity. It is involved in the biological process described with: lipid metabolic process; phototransduction; response to oxidative stress. 31 alleles are reported. The phenotypes of these alleles manifest in: photoreceptor cell R2; ommatidium; photoreceptor cell R4; rhabdomere; photoreceptor cell R6; photoreceptor cell R1; photoreceptor cell R3; eye; photoreceptor cell R5. The phenotypic classes of alleles include: increased mortality; visual behavior defective; oxidative stress response defective; phenotype; neurophysiology defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0050108	CG30108	0.674759759	0.084976338	0.999936032	NA	TRIAP1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG30108 (FBgn0050108). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:17669395..17670000. It has the cytological map location 54D4. Protein features are: Mitochondrial distribution/morphology family 35/apoptosis. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed within 00-06 hour embryonic stages, during early pupal stages.  "
FBgn0263257	Cngl	0.677018717	0.057938021	0.999936032	NA	CNGA4;CNGA1;CNGA3;CNGA2	low;low;low;low	NA	transmembrane protein	NA	"The gene Cyclic nucleotide-gated ion channel-like is referred to in FlyBase by the symbol Dmel\Cngl (CG43395, FBgn0263257). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (all unique). Gene sequence location is X:15386038..15441252. It has the cytological map location 13C1. Protein features are: Cyclic nucleotide-binding domain; Cyclic nucleotide-binding, conserved site; Cyclic nucleotide-binding-like; Ion transport domain; RmlC-like jelly roll fold. Its molecular function is described by: intracellular cyclic nucleotide activated cation channel activity; voltage-gated potassium channel activity. It is involved in the biological process described with: cation transport; transmembrane transport; regulation of membrane potential; cyclic-nucleotide-mediated signaling. 13 alleles are reported. The phenotype of these alleles manifest in: embryonic/larval brain. The phenotypic classes of alleles include: lethal; viable."
FBgn0043576	PGRP-SC1a	0.678785114	0.076606568	0.999936032	NA	PGLYRP1;PGLYRP4;PGLYRP3;PGLYRP2	moderate;moderate;low;low	NA	transmembrane protein	NA	"The gene Peptidoglycan recognition protein SC1a is referred to in FlyBase by the symbol Dmel\PGRP-SC1a (CG14746, FBgn0043576). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:8709733..8710320. It has the cytological map location 44E2. Protein features are: N-acetylmuramoyl-L-alanine amidase domain; Peptidoglycan recognition protein; Peptidoglycan recognition protein family domain, metazoa/bacteria; Peptidoglycan recognition protein, PGRP-S. Its molecular function is described by: zinc ion binding; peptidoglycan binding; N-acetylmuramoyl-L-alanine amidase activity. It is involved in the biological process described with: negative regulation of innate immune response; innate immune response; peptidoglycan catabolic process; immune response. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; immune response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed during early larval stages.  "
FBgn0063494	GstE6	0.678902607	0.066749825	0.999936032	NA	GSTT2B;GSTT1;GSTT2	moderate;moderate;moderate	NA	NA	NA	"The gene Glutathione S transferase E6 is referred to in FlyBase by the symbol Dmel\GstE6 (CG17530, FBgn0063494). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:18406011..18406761. It has the cytological map location 55C7. Protein features are: Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Thioredoxin-like fold. Its molecular function is described by: glutathione transferase activity. It is involved in the biological process described with: glutathione metabolic process. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, in adult female stages.  "
FBgn0266346	CngB	0.679402144	0.094616246	0.999936032	NA	CNGB1;CNGB3	high;moderate	NA	transmembrane protein	NA	"The gene Cyclic nucleotide-gated ion channel subunit B is referred to in FlyBase by the symbol Dmel\CngB (CG17922, FBgn0266346). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:21692691..21697152. It has the cytological map location 57F9. Protein features are: Cyclic nucleotide-binding domain; Cyclic nucleotide-binding, conserved site; Cyclic nucleotide-binding-like; Ion transport domain; RmlC-like jelly roll fold. Its molecular function is described by: intracellular cyclic nucleotide activated cation channel activity; voltage-gated potassium channel activity. It is involved in the biological process described with: cyclic-nucleotide-mediated signaling; regulation of membrane potential; transmembrane transport; cation transport. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable."
FBgn0031418	CG3609	0.682792687	0.06491478	0.999936032	DHDH	DHDH	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3609 (FBgn0031418). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:2372455..2374627. It has the cytological map location 22E1. Protein features are: NAD(P)-binding domain; Oxidoreductase, C-terminal; Oxidoreductase, N-terminal. Its molecular function is described by: oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. 10 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0001225	Hsp26	0.684345076	0.094909159	0.999936032	NA	HSPB1;CRYAB;HSPB2;HSPB8;CRYAA;HSPB3;LOC102724652;HSPB7;HSPB6	high;moderate;high;low;low;moderate;low;moderate;low	NA	NA	NA	"The gene Heat shock protein 26 is referred to in FlyBase by the symbol Dmel\Hsp26 (CG4183, FBgn0001225). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:9376418..9377427. It has the cytological map location 67B2. Protein features are: Alpha crystallin/Heat shock protein; Alpha crystallin/Hsp20 domain; HSP20-like chaperone; Small heat shock protein HSP20. Its molecular function is described by: myosin binding; unfolded protein binding. It is involved in the biological process described with: cold acclimation; chaperone-mediated protein folding; determination of adult lifespan; response to heat; protein refolding. 18 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile; long lived; chemical resistant; female fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0032839	CG10659	0.684742614	0.066433682	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG10659 (FBgn0032839). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:20024975..20025811. It has the cytological map location 38B1. Protein features are: Acyl-CoA N-acyltransferase; GNAT domain. Its molecular function is described by: N-acetyltransferase activity. It is involved in the biological process described with: nitrogen compound metabolic process. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed in adult male stages.
FBgn0034187	CG6967	0.688595121	0.101121782	0.999936032	NA	MOV10;MOV10L1	high;moderate	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG6967 (FBgn0034187). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:17062775..17066546. It has the cytological map location 53F4. Protein features are: P-loop containing nucleoside triphosphate hydrolase; Probable RNA helicase SDE3. Its molecular function is unknown. The biological processes in which it is involved are not known. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 00-06 hour embryonic stages.
FBgn0051453	pch2	0.690302067	0.098272285	0.999936032	NA	TRIP13	high	NA	NA	NA	"The gene pachytene checkpoint 2 is referred to in FlyBase by the symbol Dmel\pch2 (CG31453, FBgn0051453). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:8559540..8561764. It has the cytological map location 85A3. Protein features are: AAA+ ATPase domain; ATPase, AAA-type, conserved site; ATPase, AAA-type, core; ClpA/B family; P-loop containing nucleoside triphosphate hydrolase. Its molecular function is described by: ATP binding. It is involved in the biological process described with: meiotic recombination checkpoint. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: female fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, during early pupal stages.  "
FBgn0265590	CR44417	0.691913439	0.084688144	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44417 (FBgn0265590). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2R:17869027..17869857. It has the cytological map location 54F4. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0262484	CG43074	0.692459466	0.094354253	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG43074 (FBgn0262484). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:3483832..3484653. It has the cytological map location 63E2. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0051809	CG31809	0.693075101	0.047377943	0.999936032	HSDL1	HSDL1;HSD17B12;HSD17B3	moderate;moderate;low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG31809 (FBgn0051809). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:16853620..16858714. It has the cytological map location 36B2. Protein features are: NAD(P)-binding domain; Short-chain dehydrogenase/reductase SDR. Its molecular function is unknown. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 06-18 hour embryonic stages.
FBgn0265101	Sgt1	0.69331063	0.068831956	0.999936032	NA	SUGT1	high	NA	NA	NA	"The gene suppressor-of-G2-allele-of-skp1 is referred to in FlyBase by the symbol Dmel\Sgt1 (CG9617, FBgn0265101). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:8304190..8305274. It has the cytological map location 84F10. Protein features are: CS domain; HSP20-like chaperone; SGS domain. Its molecular function is described by: protein binding, bridging; chaperone binding. It is involved in the biological process described with: centrosome cycle; maintenance of neuroblast polarity; neuroblast proliferation; protein stabilization. 13 alleles are reported. The phenotypes of these alleles manifest in: centrosome; centriole; neuroblast; spindle. The phenotypic classes of alleles include: neuroanatomy defective; partially lethal; lethal; cell cycle defective; fertile; cell polarity defective; mitotic cell cycle defective; viable; increased mortality during development; phenotype."
FBgn0010226	GstS1	0.693686253	0.062745196	0.999936032	NA	HPGDS;GSTA3	high;moderate	NA	NA	NA	"The gene Glutathione S transferase S1 is referred to in FlyBase by the symbol Dmel\GstS1 (CG8938, FBgn0010226). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 2R:17093246..17099501. It has the cytological map location 53F7-53F8. Protein features are: Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Thioredoxin-like fold. Its molecular function is described by: glutathione transferase activity; glutathione peroxidase activity. It is involved in the biological process described with: glutathione metabolic process; metabolic process; response to oxidative stress. 63 alleles are reported. The phenotypes of these alleles manifest in: wing; macrochaeta; embryonic/larval hemocyte; eye. The phenotypic classes of alleles include: increased mortality; phenotype; viable; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of moderately high expression.  Peak expression observed during late pupal stages.  "
FBgn0063670	CG40228	0.693853692	0.07895101	0.999936032	NA	ELOF1	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG40228 (FBgn0063670). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 3L:27082091..27083906. Protein features are: Transcription elongation factor 1. Its molecular function is described by: RNA polymerase II core binding. It is involved in the biological process described with: chromatin-mediated maintenance of transcription; transcription elongation from RNA polymerase II promoter. 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages.
FBgn0033000	CG14464	0.693894773	0.067003776	0.999936032	NA	ARL14EP;ARL14EPL	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14464 (FBgn0033000). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:4829246..4830587. It has the cytological map location 41C3. Protein features are: ARF7 effector protein, C-terminal; ARL14 effector protein. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages.  "
FBgn0032066	LManIII	0.694401856	0.061562022	0.999936032	NA	MAN2B1;MAN2B2	moderate;low	NA	NA	NA	"The gene Lysosomal ‘±-mannosidase III is referred to in FlyBase by the symbol Dmel\LManIII (CG9463, FBgn0032066). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:8765273..8768710. It has the cytological map location 29F1. Protein features are: Galactose mutarotase-like domain; Glycoside hydrolase 38/57, N-terminal domain; Glycoside hydrolase families 57/38, central domain; Glycoside hydrolase family 38, N-terminal domain; Glycoside hydrolase family 38, central domain; Glycoside hydrolase/deacetylase, beta/alpha-barrel; Glycosyl hydrolase family 38, C-terminal. Its molecular function is described by: alpha-mannosidase activity; carbohydrate binding. It is involved in the biological process described with: mannose metabolic process; protein deglycosylation. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed during late larval stages.  "
FBgn0054010	Glyat	0.696064873	0.097569875	0.999936032	NA	GLYATL3	moderate	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG34010 (FBgn0054010). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:8009603..8010652. It has the cytological map location 28D3. Protein features are: Acyl-CoA N-acyltransferase; FR47-like; GNAT domain. Its molecular function is described by: N-acetyltransferase activity. It is involved in the biological process described with: . 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-18 embryonic stages.
FBgn0086675	fne	0.696234418	0.05730154	0.999936032	NA	ELAVL2;ELAVL4;ELAVL3;ELAVL1	high;high;moderate;moderate	NA	NA	NA	"The gene found in neurons is referred to in FlyBase by the symbol Dmel\fne (CG4396, FBgn0086675). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (2 unique). Gene sequence location is X:12917477..12950417. It has the cytological map location 11D3-11D4. Protein features are: Paraneoplastic encephalomyelitis antigen; RNA recognition motif domain; Splicing factor ELAV/Hu; Splicing factor ELAV/Hu, RNA recognition motif 1. Its molecular function is described by: poly(U) RNA binding; mRNA binding. It is involved in the biological process described with: male courtship behavior; regulation of RNA metabolic process; regulation of mRNA processing. 18 alleles are reported. The phenotypes of these alleles manifest in: mushroom body beta-lobe; prothoracic leg; wing vein. The phenotypic classes of alleles include: mating behavior defective; courtship behavior defective; partially lethal; pain response defective; lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages.  "
FBgn0263400	CG43446	0.699040506	0.095856716	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG43446 (FBgn0263400). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:20986504..20987936. It has the cytological map location 93B3. Protein features are: Zinc finger, FYVE/PHD-type; Zinc finger, RING/FYVE/PHD-type. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported."
FBgn0026374	Rhp	0.699937572	0.085653097	0.999936032	RHPN2	RHPN2;RHPN1;RHPN2P1	high;moderate;moderate	NA	NA	NA	"The gene Rhophilin is referred to in FlyBase by the symbol Dmel\Rhp (CG8497, FBgn0026374). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:15788897..15793632. It has the cytological map location 13E18. Protein features are: BRO1 domain; HR1 rho-binding repeat; PDZ domain. Its molecular function is unknown. It is involved in the biological process described with: signal transduction. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 06-24 hour embryonic stages, during late pupal stages.  "
FBgn0036023	CG18179	0.701255612	0.059505956	0.999936032	NA	C1S;PROC	low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG18179 (FBgn0036023). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:9639271..9640140. It has the cytological map location 67C3. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during early larval stages, during early pupal stages.  "
FBgn0052641	CG32641	0.703072394	0.064565734	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG32641 (FBgn0052641). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:13184478..13184996. It has the cytological map location 11E3. Protein features are: DnaJ domain; DnaJ domain, conserved site. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, during late larval stages, during early pupal stages, in stages of adults of both sexes.  "
FBgn0025678	CaBP1	0.703385437	0.060900095	0.999936032	NA	PDIA6	high	NA	NA	NA	"The gene calcium-binding protein 1 is referred to in FlyBase by the symbol Dmel\CaBP1 (CG5809, FBgn0025678). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:16354886..16356735. It has the cytological map location 35F12. Protein features are: Disulphide isomerase; Thioredoxin domain; Thioredoxin, conserved site; Thioredoxin-like fold. Its molecular function is described by: protein disulfide isomerase activity. It is involved in the biological process described with: protein folding; sleep; response to endoplasmic reticulum stress; cell redox homeostasis; positive regulation of apoptotic cell clearance. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-18 hour embryonic stages, during early larval stages, during early pupal stages.  "
FBgn0053196	dpy	0.706837669	0.09151121	0.999936032	NA	LTBP1	high	Maybe TF	transmembrane protein	NA	"The gene dumpy is referred to in FlyBase by the symbol Dmel\dpy (CG33196, FBgn0053196). It is a protein_coding_gene from Drosophila melanogaster. It has 16 annotated transcripts and 16 polypeptides (all unique). Gene sequence location is 2L:4477462..4614300. It has the cytological map location 24F4-25A1. Protein features are: Cysteine-rich repeat; EGF domain; EGF-like calcium-binding domain; EGF-like calcium-binding, conserved site; EGF-like domain; EGF-like, conserved site; EGF-type aspartate/asparagine hydroxylation site; Follistatin-like, N-terminal; Growth factor receptor cysteine-rich domain; Zinc finger, NF-X1-type; Zona pellucida domain. Its molecular function is described by: zinc ion binding; transcription factor activity, sequence-specific DNA binding; extracellular matrix structural constituent; calcium ion binding. It is involved in the biological process described with: regulation of imaginal disc-derived wing size; chitin-based cuticle attachment to epithelium; chitin-based embryonic cuticle biosynthetic process; regulation of transcription, DNA-templated; lateral inhibition; open tracheal system development; apposition of dorsal and ventral imaginal disc-derived wing surfaces. 330 alleles are reported. The phenotypes of these alleles manifest in: head; embryonic/larval dorsal branch; sensory organ cell; endocuticle; adult procephalic segment; adult abdomen; cuticular specialization; muscle attachment site; prepupa; lateral trunk anterior branch. The phenotypic classes of alleles include: increased mortality; lethal; modifier of variegation; phenotype; increased mortality during development. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0029710	CG3568	0.708371492	0.089760961	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG3568 (FBgn0029710). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:4542630..4544497. It has the cytological map location 4C7. Protein features are: Protein of unknown function DUF4804. Its molecular function is described by: . It is involved in the biological process described with: . 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed during early pupal stages.
FBgn0265140	Meltrin	0.708477359	0.082820627	0.999936032	NA	ADAM12;ADAM19;ADAM15;ADAM8;ADAM33;ADAM28;ADAM9;ADAM7;ADAM11;ADAM22;ADAM20;ADAM21;ADAM30;ADAMDEC1;ADAM5;ADAM32;ADAM29;ADAM2;ADAM18;ADAM23	high;high;moderate;moderate;moderate;moderate;moderate;moderate;low;low;moderate;moderate;moderate;moderate;moderate;low;low;low;low;low	NA	transmembrane protein	NA	"The gene Meltrin is referred to in FlyBase by the symbol Dmel\Meltrin (CG7649, FBgn0265140). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3R:14664907..14697292. It has the cytological map location 88C10-88D1. Protein features are: ADAM, cysteine-rich; Disintegrin domain; EGF-like domain; EGF-like, conserved site; Metallopeptidase, catalytic domain; Peptidase M12B, ADAM/reprolysin; Peptidase M12B, propeptide; Reprolysin domain, adamalysin-type. Its molecular function is described by: identical protein binding; metalloendopeptidase activity. It is involved in the biological process described with: membrane protein ectodomain proteolysis; protein oligomerization. 34 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: wild-type; viable; lethal."
FBgn0038702	CG3739	0.708955939	0.056465896	0.999936032	NA	PRSS16	moderate	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG3739 (FBgn0038702). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:19393360..19395188. It has the cytological map location 92A3. Protein features are: Alpha/Beta hydrolase fold; Peptidase S28. Its molecular function is described by: serine-type peptidase activity; dipeptidyl-peptidase activity. It is involved in the biological process described with: proteolysis. 2 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed in adult male stages.
FBgn0030148	CG3106	0.709540867	0.058246549	0.999936032	NA	PTPN9	low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3106 (FBgn0030148). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:9659095..9662903. It has the cytological map location 8F6. Protein features are: Acyltransferase 3; Nose resistant-to-fluoxetine protein, N-terminal. Its molecular function is described by: transferase activity, transferring acyl groups other than amino-acyl groups. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal - majority die; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0024836	stan	0.710150094	0.055276241	0.999936032	NA	CELSR2;CELSR1;CELSR3;MIR4793	high;moderate;moderate;moderate	NA	transmembrane protein	GPCR	"The gene starry night is referred to in FlyBase by the symbol Dmel\stan (CG11895, FBgn0024836). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (5 unique). Gene sequence location is 2R:10673345..10721138. It has the cytological map location 47B6-47B7. Protein features are: Cadherin; Cadherin conserved site; Cadherin-like; Concanavalin A-like lectin/glucanase domain; EGF-like calcium-binding domain; EGF-like domain; EGF-like, conserved site; GAIN domain, N-terminal; GPCR, family 2, extracellular hormone receptor domain; GPCR, family 2, secretin-like; GPCR, family 2-like; GPS motif; Laminin EGF domain; Laminin G domain. Its molecular function is described by: receptor activity; signal transducer activity, downstream of receptor; calcium ion binding; transmembrane signaling receptor activity; G-protein coupled receptor activity; cell adhesion molecule binding. It is involved in the biological process described with 28 unique terms, many of which group under: cell adhesion; regulation of organ morphogenesis; open tracheal system development; synapse organization; head development; biological adhesion; cell-cell adhesion via plasma-membrane adhesion molecules; cell-cell adhesion; segmentation; central nervous system development. 69 alleles are reported. The phenotypes of these alleles manifest in: neuromuscular junction; neuron part; photoreceptor cell R4; developing material anatomical entity; cuticle; synapse; mushroom body calyx; developing embryonic structure; cell projection; wing hair; plasma membrane bounded cell projection; adult external mesothorax. The phenotypic classes of alleles include: viable; phenotype; lethal - all die before end of first instar larval stage; visible; increased mortality; fertile; some die during embryonic stage; planar polarity defective; neuroanatomy defective; body size defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 06-18 hour embryonic stages, at stages throughout the pupal period.  "
FBgn0039316	CG11893	0.71045156	0.057714461	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11893 (FBgn0039316). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:25289889..25291366. It has the cytological map location 96C9. Protein features are: CHK kinase-like; Protein kinase-like domain; Protein of unknown function DUF227. Its molecular function is unknown. It is involved in the biological process described with: chaeta development; wing disc development. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable; planar polarity defective; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very low expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0040532	CG8369	0.710558675	0.086372309	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8369 (FBgn0040532). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:8822008..8822838. It has the cytological map location 85B2. Protein features are: Kazal domain. Its molecular function is unknown. It is involved in the biological process described with: wing disc dorsal/ventral pattern formation. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late larval stages, during late pupal stages, in adult male stages.  "
FBgn0034354	GstE11	0.712549852	0.064548475	0.999936032	NA	GSTT2B;GSTT1;MARS;VARS;GSTT2;EEF1G;EEF1E1	low;low;low;low;low;low;low	NA	NA	NA	"The gene Glutathione S transferase E11 is referred to in FlyBase by the symbol Dmel\GstE11 (CG5224, FBgn0034354). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:18503608..18505025. It has the cytological map location 55D1. Protein features are: Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Thioredoxin-like fold. Its molecular function is described by: glutathione transferase activity. It is involved in the biological process described with: glutathione metabolic process. 9 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; embryonic/larval neuroblast; mesothoracic tergum. The phenotypic classes of alleles include: neuroanatomy defective; lethal; fertile; flightless; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 06-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0038083	CG5999	0.713278597	0.062033145	0.999936032	UGT1A3	UGT1A3;UGT2B10;UGT1A1;UGT3A1;UGT8;UGT2B4;UGT2B15;UGT2B28;UGT2A2;UGT3A2;UGT2B17;UGT2B11;UGT2A3;UGT2B7	moderate;low;low;low;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5999 (FBgn0038083). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:12741958..12743680. It has the cytological map location 87C8. Protein features are: UDP-glucuronosyl/UDP-glucosyltransferase. Its molecular function is described by: glucuronosyltransferase activity. It is involved in the biological process described with: metabolic process. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal - all die during P-stage; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0267472	CR45822	0.714154653	0.044676632	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45822 (FBgn0267472). It is a non_protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts. Gene sequence location is 3L:7355717..7356598. It has the cytological map location 65F6. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0033945	CG12868	0.715264471	0.057993638	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12868 (FBgn0033945). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:14604549..14605297. It has the cytological map location 51B6. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 06-18 hour embryonic stages, during late larval stages, during early pupal stages.  "
FBgn0039748	CG15529	0.716164405	0.08672932	0.999936032	NA	BLNK	high	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG15529 (FBgn0039748). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:30152059..30153699. It has the cytological map location 99D9-99E1. Protein features are: SH2 domain. Its molecular function is unknown. It is involved in the biological process described with: immune response; transmembrane receptor protein tyrosine kinase signaling pathway; intracellular signal transduction. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed in adult female stages.
FBgn0031381	Npc2a	0.718417236	0.061408283	0.999936032	NA	NPC2;MIR4709	high;moderate	NA	NA	NA	"The gene Niemann-Pick type C-2a is referred to in FlyBase by the symbol Dmel\Npc2a (CG7291, FBgn0031381). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:1988290..1988940. It has the cytological map location 22B8. Protein features are: Immunoglobulin E-set; MD-2-related lipid-recognition domain; ML domain, Npc2 like. Its molecular function is described by: sterol binding; lipid antigen binding; lipoteichoic acid binding; peptidoglycan binding; lipopolysaccharide binding. It is involved in the biological process described with: peptidoglycan recognition protein signaling pathway; sterol transport; ecdysteroid biosynthetic process; intracellular cholesterol transport; sterol homeostasis; synaptic target recognition. 12 alleles are reported. The phenotype of these alleles manifest in: Malpighian tubule. The phenotypic classes of alleles include: fertile; short lived; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-06 and 12-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0050371	CG30371	0.718768155	0.05664788	0.999936032	NA	TMPRSS7;ST14;TMPRSS6;F10	low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG30371 (FBgn0050371). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:8267643..8269334. It has the cytological map location 44C3. Protein features are: CUB domain; Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 5 alleles are reported. The phenotypes of these alleles manifest in: antenna; leg. The phenotypic classes of alleles include: viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0266084	Fhos	0.719514018	0.075322089	0.999936032	NA	FHOD3;FHOD1	high;high	NA	transmembrane protein	NA	"The gene Formin homology 2 domain containing is referred to in FlyBase by the symbol Dmel\Fhos (CG42610, FBgn0266084). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (8 unique). Gene sequence location is 3L:8753619..8798719. It has the cytological map location 66D12-66D15. Protein features are: Armadillo-like helical; Armadillo-type fold; Diaphanous autoregulatory (DAD) domain; Formin, FH2 domain; Rho GTPase-binding/formin homology 3 (GBD/FH3) domain. Its molecular function is described by: actin binding. It is involved in the biological process described with: positive regulation of stress fiber assembly; imaginal disc-derived wing morphogenesis; muscle cell cellular homeostasis; wound healing, spreading of cells; muscle system process; trachea morphogenesis; salivary gland histolysis; positive regulation of cell migration; positive regulation of substrate adhesion-dependent cell spreading; programmed cell death involved in cell development. 41 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval salivary gland; sarcomere; myofibril; macrophage; wing disc; actin filament bundle; stress fiber; indirect flight muscle. The phenotypic classes of alleles include: flight defective; phenotype; increased mortality during development; stress response defective."
FBgn0265979	CR44758	0.72039956	0.080040805	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44758 (FBgn0265979). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2R:22312876..22316604. It has the cytological map location 58D3. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0000120	Arr1	0.720581989	0.0808863	0.999936032	NA	ARRB1;SAG;ARRB2;ARR3	moderate;moderate;moderate;moderate	NA	NA	NA	"The gene Arrestin 1 is referred to in FlyBase by the symbol Dmel\Arr1 (CG5711, FBgn0000120). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:18078269..18081307. It has the cytological map location 36E3. Protein features are: Arrestin; Arrestin C-terminal-like domain; Arrestin, N-terminal; Arrestin, conserved site; Arrestin-like, N-terminal; Immunoglobulin E-set. Its molecular function is described by: opsin binding. It is involved in the biological process described with: deactivation of rhodopsin mediated signaling; sensory perception of smell; photoreceptor cell maintenance; endocytosis; metarhodopsin inactivation; desensitization of G-protein coupled receptor protein signaling pathway by arrestin. 9 alleles are reported. The phenotypes of these alleles manifest in: eye photoreceptor cell; rhabdomere. The phenotypic classes of alleles include: smell perception defective; viable; increased cell death; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during late pupal stages, in stages of adults of both sexes.  "
FBgn0033778	CG3790	0.72103237	0.066738501	0.999936032	NA	SLC22A16;SLC22A4;SLC22A5;SLC22A3	moderate;moderate;moderate;high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG3790 (FBgn0033778). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:12872787..12875012. It has the cytological map location 49D6. Protein features are: Major facilitator superfamily domain; Major facilitator,  sugar transporter-like. Its molecular function is described by: organic anion transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; response to ethanol. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; developmental rate defective; fertile; chemical sensitive. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of very low expression.  Peak expression observed during late pupal stages, in stages of adults of both sexes.  "
FBgn0000318	cl	0.721650205	0.053337323	0.999936032	NA	TXNDC17	high	NA	NA	NA	"The gene clot is referred to in FlyBase by the symbol Dmel\cl (CG11024, FBgn0000318). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2L:5520135..5521382. It has the cytological map location 25E5. Protein features are: Protein of unknown function DUF953, thioredoxin-like; Thioredoxin-like fold. Its molecular function is described by: protein-disulfide reductase activity. It is involved in the biological process described with: eye pigment biosynthetic process. 19 alleles are reported. The phenotypes of these alleles manifest in: pigment cell; Malpighian tubule. The phenotypic classes of alleles include: fertile; eye color defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in stages of adults of both sexes.  "
FBgn0033635	Prip	0.72805289	0.054091669	0.999936032	NA	AQP1;AQP2;AQP8;AQP4;AQP5;AQP6;MIP	high;moderate;moderate;moderate;low;low;low	NA	transmembrane protein	NA	"The gene Prip is referred to in FlyBase by the symbol Dmel\Prip (CG7777, FBgn0033635). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 2R:11436243..11442216. It has the cytological map location 47F12-47F13. Protein features are: Aquaporin transporter; Aquaporin-like; Major intrinsic protein. Its molecular function is described by: water channel activity; channel activity. It is involved in the biological process described with: ion transmembrane transport; transmembrane transport. 8 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0034160	CG5550	0.72841825	0.053202855	0.999936032	FCN1	FCN3;FCN2;FCN1;TNR;TNXB;TNC;ANGPTL4;FGB;TNN;ANGPTL7;FGL1;FIBCD1;MFAP4;ANGPTL5;ANGPTL3;ANGPTL1;FGG;ANGPTL2;ANGPT4;ANGPTL6;FGA;ANGPT1;ANGPT2;FGL2	high;high;high;high;low;moderate;moderate;moderate;moderate;low;low;low;moderate;low;low;moderate;low;low;low;low;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5550 (FBgn0034160). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:16816589..16817577. It has the cytological map location 53D10. Protein features are: Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain; Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1; Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2; Fibrinogen, conserved site. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0025726	unc-13	0.728921087	0.06078587	0.999936032	NA	UNC13B;UNC13A;UNC13C	high;high;high	NA	NA	NA	"The gene unc-13 is referred to in FlyBase by the symbol Dmel\unc-13 (CG2999, FBgn0025726). It is a protein_coding_gene from Drosophila melanogaster. It has 7 annotated transcripts and 7 polypeptides (6 unique). Gene sequence location is 4:867824..912331. It has the cytological map location 102E5-102F1. Protein features are: C2 domain; Calcium-dependent secretion activator domain; Mammalian uncoordinated homology 13, domain 2; Mammalian uncoordinated homology 13, subgroup, domain 2; Munc13 homology 1; Protein kinase C-like, phorbol ester/diacylglycerol-binding domain; Uncoordinated protein 13 (Unc-13). Its molecular function is described by: syntaxin-1 binding; diacylglycerol binding; protein N-terminus binding; calmodulin binding. It is involved in the biological process described with: lateral inhibition; synaptic vesicle exocytosis; synaptic vesicle priming; intracellular signal transduction; neurotransmitter secretion; chemical synaptic transmission. 17 alleles are reported. The phenotypes of these alleles manifest in: chaeta; synaptic vesicle; trichogen cell. The phenotypic classes of alleles include: increased mortality; fertile; phenotype; feeding behavior defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed at stages throughout the pupal period.  "
FBgn0036847	CNPYb	0.730623828	0.066448005	0.999936032	NA	CNPY4;CNPY3	high;moderate	NA	NA	NA	"The gene Canopy b is referred to in FlyBase by the symbol Dmel\CNPYb (CG11577, FBgn0036847). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:19094890..19096217. It has the cytological map location 75F7. Protein features are: Domain of unknown function DUF3456. Its molecular function is described by: chaperone binding. It is involved in the biological process described with: chaperone-mediated protein folding. 2 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.  "
FBgn0037786	CG5361	0.731744586	0.077232924	0.999936032	NA	ALPPL2;ALPI;ALPP;ALPL	moderate;moderate;moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG5361 (FBgn0037786). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:10073821..10075373. It has the cytological map location 85F9. Protein features are: Alkaline phosphatase; Alkaline phosphatase-like, alpha/beta/alpha; Alkaline-phosphatase-like, core domain. Its molecular function is described by: phosphatase activity. It is involved in the biological process described with: metabolic process. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed during late larval stages, in adult male stages.  "
FBgn0062412	Ctr1B	0.731835395	0.051214227	0.999936032	NA	SLC31A1;SLC31A2	moderate;moderate	NA	transmembrane protein	NA	"The gene Copper transporter 1B is referred to in FlyBase by the symbol Dmel\Ctr1B (CG7459, FBgn0062412). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:8317612..8319205. It has the cytological map location 84F11. Protein features are: Ctr copper transporter. Its molecular function is described by: copper uptake transmembrane transporter activity; copper ion transmembrane transporter activity. It is involved in the biological process described with: cellular copper ion homeostasis; response to metal ion; copper ion transmembrane transport; copper ion transport. 20 alleles are reported. The phenotypes of these alleles manifest in: eye; ommatidium; wing; adult cuticle. The phenotypic classes of alleles include: increased mortality; visible; increased mortality during development; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed at stages throughout the larval period, during early pupal stages, in stages of adults of both sexes.  "
FBgn0266853	CR45314	0.737913159	0.060820506	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45314 (FBgn0266853). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 2R:18057915..18059075. It has the cytological map location 55B2. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0034045	CG8249	0.741521243	0.055384333	0.999936032	NA	SLC2A8;SLC2A6	moderate;moderate	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8249 (FBgn0034045). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:15842760..15847362. It has the cytological map location 52C8. Protein features are: Major facilitator superfamily domain; Major facilitator,  sugar transporter-like; Sugar transporter, conserved site; Sugar/inositol transporter. Its molecular function is described by: glucose transmembrane transporter activity; sugar:proton symporter activity. It is involved in the biological process described with: glucose import; hexose transmembrane transport. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during pupal stage; partially lethal - majority die; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 06-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0260632	dl	0.741661775	0.055232667	0.999936032	NA	RELA;REL;RELB;NFKB1	high;moderate;moderate;low	DNA-binding with transcription factor activity(RHD|TIG)	NA	NA	"The gene dorsal is referred to in FlyBase by the symbol Dmel\dl (CG6667, FBgn0260632). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (2 unique). Gene sequence location is 2L:17436830..17450364. It has the cytological map location 36C8-36C9. Protein features are: Dorsal-related immunity factor Dif; IPT domain; Immunoglobulin E-set; Immunoglobulin-like fold; NF-kappa-B/Dorsal; NFkappaB IPT domain; Rel homology dimerisation domain; Rel homology domain (RHD), DNA-binding domain; Rel homology domain, conserved site; WD40/YVTN repeat-like-containing domain; p53-like transcription factor, DNA-binding. Its molecular function is described by: RNA polymerase II regulatory region sequence-specific DNA binding; repressing transcription factor binding; transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding; transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; sequence-specific DNA binding; chromatin binding; high mobility group box 1 binding; protein binding. It is involved in the biological process described with 31 unique terms, many of which group under: nervous system development; signal transduction; RNA processing; cell motility; response to cytokine; single-organism carbohydrate metabolic process; cell development; regulation of multicellular organismal process; hemocyte differentiation; reproductive process; response to organic substance; circulatory system development. 145 alleles are reported. The phenotypes of these alleles manifest in: neuron part; epithelial tube; macrochaeta; ventral furrow; embryonic imaginal precursor; embryonic head; endoderm; nerve; tracheal system; compound sense organ; cell projection. The phenotypic classes of alleles include: increased mortality; increased mortality during development; phenotype; sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages.  "
FBgn0040104	lectin-24A	0.743084904	0.076224129	0.999936032	NA	SFTPA1;SFTPA2;SFTPD;COLEC11	high;high;moderate;high	NA	NA	NA	"The gene lectin-24A is referred to in FlyBase by the symbol Dmel\lectin-24A (CG3410, FBgn0040104). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:3716800..3717773. It has the cytological map location 24C1. Protein features are: C-type lectin fold; C-type lectin-like; C-type lectin-like/link domain. Its molecular function is described by: carbohydrate binding; galactose binding. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: some die during pupal stage; partially lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very low expression to a trough of no expression detected.  Peak expression observed within 06-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0011770	Gip	0.743155129	0.05135575	0.999936032	HYI	HYI	high	NA	NA	NA	"The gene GIP-like is referred to in FlyBase by the symbol Dmel\Gip (CG2227, FBgn0011770). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:10328877..10329872. It has the cytological map location 9B7. Protein features are: Hydroxypyruvate isomerase-like; Xylose isomerase-like, TIM barrel domain. Its molecular function is described by: hydroxypyruvate isomerase activity. It is involved in the biological process described with: glyoxylate metabolic process. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed during early larval stages.  "
FBgn0038165	Task6	0.744535348	0.031342578	0.999936032	NA	KCNK9;KCNK3;KCNK15	moderate;moderate;moderate	NA	transmembrane protein	NA	"The gene TWIK-related acid-sensitive K<sup>+</sup> channel 6 is referred to in FlyBase by the symbol Dmel\Task6 (CG9637, FBgn0038165). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3R:13667046..13674542. It has the cytological map location 87F7. Protein features are: Potassium channel domain; Two pore domain potassium channel; Two pore domain potassium channel, TASK family. Its molecular function is described by: potassium channel activity; potassium ion leak channel activity; protein heterodimerization activity. It is involved in the biological process described with: stabilization of membrane potential; potassium ion transmembrane transport. 6 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: lethal - all die during P-stage; viable; visible; lethal; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult male stages.  "
FBgn0020622	Pi3K21B	0.74502826	0.055233263	0.999936032	NA	PIK3R3;PIK3R1;PIK3R2	high;moderate;moderate	NA	NA	NA	"The gene Pi3K21B is referred to in FlyBase by the symbol Dmel\Pi3K21B (CG2699, FBgn0020622). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 2L:297880..305233. It has the cytological map location 21B8. Protein features are: PI3K p85 subunit, C-terminal SH2 domain; PI3K p85 subunit, N-terminal SH2 domain; PI3K p85 subunit, inter-SH2 domain; PI3K p85/p55 subunit; SH2 domain. Its molecular function is described by: 1-phosphatidylinositol-3-kinase regulator activity; kinase binding; phosphatidylinositol 3-kinase regulator activity; insulin receptor substrate binding. It is involved in the biological process described with: phosphatidylinositol phosphorylation; positive regulation of growth; regulation of cell size; insulin receptor signaling pathway; positive regulation of cell size; regulation of phosphatidylinositol 3-kinase activity; regulation of organ growth; protein phosphorylation; regulation of cell proliferation; lipid phosphorylation. 15 alleles are reported. The phenotypes of these alleles manifest in: wing; cell cycle; mushroom body neuroblast; egg chamber; embryonic/larval neuroblast; embryonic/larval ganglionic branch; embryonic/larval salivary gland; embryonic/larval fat body. The phenotypic classes of alleles include: body size defective; some die during embryonic stage; cell size defective; chemical sensitive; wild-type; increased mortality; visible; viable; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.  "
FBgn0259237	CG42335	0.747515976	0.048943242	0.999936032	NA	TRHDE;LVRN;ANPEP;ENPEP;LNPEP;ERAP1;ERAP2	moderate;moderate;moderate;low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG42335 (FBgn0259237). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:21758764..21769301. It has the cytological map location 93F9. Protein features are: Aminopeptidase N-type; ERAP1-like C-terminal domain; Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase; Peptidase M1, membrane alanine aminopeptidase, N-terminal. Its molecular function is described by: zinc ion binding; metalloaminopeptidase activity; peptide binding. It is involved in the biological process described with: peptide catabolic process; proteolysis. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, in stages of adults of both sexes.  "
FBgn0051950	CG31950	0.751870908	0.060681537	0.999936032	NA	NAA38	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31950 (FBgn0051950). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:2878344..2879001. It has the cytological map location 23C1. Protein features are: LSM domain; LSM domain containing 1; LSM domain, eukaryotic/archaea-type. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 06-12 hour embryonic stages, in adult male stages.  "
FBgn0035189	CG9119	0.754364161	0.04733894	0.999936032	C11orf54	C11orf54	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9119 (FBgn0035189). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:1203316..1204795. It has the cytological map location 61F3. Protein features are: Domain of unknown function DUF1907. Its molecular function is described by: hydrolase activity, acting on ester bonds; zinc ion binding. It is involved in the biological process described with: . 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, in adult male stages.  "
FBgn0265185	CG44250	0.755213727	0.044628901	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG44250 (FBgn0265185). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:12950404..12952293. It has the cytological map location 49E4. Protein features are: DM9 repeat; Domain of unknown function DUF3421. Its molecular function is described by: . It is involved in the biological process described with: . 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable.
FBgn0013276	Hsp70Ab	0.756530995	0.0589979	0.999936032	NA	HSPA1A;HSPA1B;HSPA1L;HSPA6;HSPA8;HSPA2;HSPA5	high;moderate;moderate;moderate;low;low;low	NA	NA	NA	"The gene Heat-shock-protein-70Ab is referred to in FlyBase by the symbol Dmel\Hsp70Ab (CG18743, FBgn0013276). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:11958535..11960909. It has the cytological map location 87A3. Protein features are: Heat shock protein 70 family; Heat shock protein 70, conserved site; Heat shock protein 70kD, C-terminal domain; Heat shock protein 70kD, peptide-binding domain. Its molecular function is unknown. It is involved in the biological process described with: heat shock-mediated polytene chromosome puffing; response to heat; response to hypoxia; response to unfolded protein. 13 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed at stages throughout the pupal period.  "
FBgn0001224	Hsp23	0.757998554	0.071318618	0.999936032	NA	HSPB2;CRYAB;HSPB8;HSPB1;HSPB3;HSPB6;HSPB7;LOC102724652;CRYAA	high;moderate;low;low;moderate;low;moderate;low;low	NA	NA	NA	"The gene Heat shock protein 23 is referred to in FlyBase by the symbol Dmel\Hsp23 (CG4463, FBgn0001224). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:9381882..9382765. It has the cytological map location 67B3. Protein features are: Alpha crystallin/Heat shock protein; Alpha crystallin/Hsp20 domain; HSP20-like chaperone; Small heat shock protein HSP20. Its molecular function is described by: protein binding; actin binding; unfolded protein binding. It is involved in the biological process described with: chaperone-mediated protein folding; cold acclimation; response to heat; response to hypoxia; protein refolding. 29 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval heart; sarcomere; mitochondrion. The phenotypic classes of alleles include: viable; cold stress response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of moderate expression.  Peak expression observed during late larval stages, at stages throughout the pupal period.  "
FBgn0263080	CG43348	0.759968334	0.049238167	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG43348 (FBgn0263080). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:1199412..1199924. It has the cytological map location 21F2. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported.
FBgn0040837	CG8620	0.761223206	0.062535359	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8620 (FBgn0040837). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:7158099..7158874. It has the cytological map location 65E6. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, in adult male stages.  "
FBgn0264821	CR44029	0.762677237	0.067709704	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44029 (FBgn0264821). It is a non_protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts. Gene sequence location is 4:879374..884752. It has the cytological map location 102E5. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0264815	Pde1c	0.764355675	0.061332955	0.999936032	NA	PDE1A;PDE1B;PDE1C	high;moderate;moderate	NA	NA	NA	"The gene Phosphodiesterase 1c is referred to in FlyBase by the symbol Dmel\Pde1c (CG44007, FBgn0264815). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (8 unique). Gene sequence location is 2L:11814156..11928572. It has the cytological map location 33A3-33A5. Protein features are: 3'5'-cyclic nucleotide phosphodiesterase; 3'5'-cyclic nucleotide phosphodiesterase N-terminal; 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain; 3'5'-cyclic nucleotide phosphodiesterase, conserved site; HD/PDEase domain. Its molecular function is described by: 3',5'-cyclic-AMP phosphodiesterase activity; calmodulin binding; calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity; 3',5'-cyclic-GMP phosphodiesterase activity. It is involved in the biological process described with: multicellular organism reproduction; cAMP metabolic process; male mating behavior; signal transduction; cGMP metabolic process. 38 alleles are reported. The phenotypes of these alleles manifest in: myofibril; trichogen cell. The phenotypic classes of alleles include: fertile; short lived; viable; male sterile; phenotype; mating defective; visible; pain response defective."
FBgn0005655	PCNA	0.770965938	0.066564098	0.999936032	NA	PCNA	high	NA	NA	NA	"The gene Proliferating cell nuclear antigen is referred to in FlyBase by the symbol Dmel\PCNA (CG9193, FBgn0005655). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:20261754..20262883. It has the cytological map location 56F11. Protein features are: Proliferating cell nuclear antigen, PCNA; Proliferating cell nuclear antigen, PCNA, C-terminal; Proliferating cell nuclear antigen, PCNA, N-terminal; Proliferating cell nuclear antigen, PCNA, conserved site. Its molecular function is described by: DNA polymerase processivity factor activity; DNA binding. It is involved in the biological process described with: DNA replication; translesion synthesis; eggshell chorion gene amplification; mismatch repair; regulation of DNA replication; leading strand elongation; DNA-dependent DNA replication; nucleotide-excision repair; antimicrobial humoral response; mitotic spindle organization. 53 alleles are reported. The phenotypes of these alleles manifest in: gonad; reproductive system; embryonic/larval protocerebrum; intracellular organelle part; embryonic/larval brain; ovary; single-organism cellular process; ganglion mother cell; perineurium; prothoracic metatarsus; chromosome, centromeric region; membrane-bounded organelle; mitotic metaphase. The phenotypic classes of alleles include: phenotype; increased mortality during development; increased mortality; stress response defective; lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 00-12 hour embryonic stages, in adult female stages.  "
FBgn0261788	Ank2	0.774715532	0.056208019	0.999936032	NA	ANK2;ANK3;ANK1	high;moderate;moderate	NA	NA	NA	"The gene Ankyrin 2 is referred to in FlyBase by the symbol Dmel\Ank2 (CG42734, FBgn0261788). It is a protein_coding_gene from Drosophila melanogaster. It has 20 annotated transcripts and 20 polypeptides (all unique). Gene sequence location is 3L:7655389..7718395. It has the cytological map location 66A10-66A9. Protein features are: Ankyrin repeat; Ankyrin repeat-containing domain; Death domain; Death-like domain; ZU5 domain. Its molecular function is described by: cytoskeletal protein binding; spectrin binding. It is involved in the biological process described with: signal transduction; neuron cellular homeostasis; neuromuscular junction development; microtubule cytoskeleton organization; negative regulation of neuromuscular synaptic transmission; axon extension; sensory perception of sound; short-term memory; positive regulation of synaptic growth at neuromuscular junction. 41 alleles are reported. The phenotypes of these alleles manifest in: NMJ bouton; type Ib motor neuron; synapse; microtubule; embryonic/larval neuromuscular junction; axon; neuromuscular junction. The phenotypic classes of alleles include: neuroanatomy defective; stress response defective; neurophysiology defective; lethal - all die before end of prepupal stage; phenotype; increased mortality during development."
FBgn0085232	CG34203	0.774928177	0.062337446	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG34203 (FBgn0085232). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:21281063..21281656. It has the cytological map location 57D6-57D7. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed during late pupal stages, in stages of adults of both sexes.  "
FBgn0259896	NimC1	0.777590069	0.035946135	0.999936032	NA	ANGPTL5;ANGPTL3;TNXB;FGG;TNC;ANGPTL2;TNN;ANGPTL7;ANGPT2;TNR;ANGPTL1;FCN3;ANGPTL4;FIBCD1;FGB;ANGPT4;FGA;ANGPTL6;ANGPT1;FGL1;FGL2;FCN2;TNFRSF21;TNFRSF1B;TNFRSF11B;MEGF10;SCARF1;SCARF2;MEGF6;TNFAIP6;PEAR1;MEGF11;DKK2	low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low;low	NA	transmembrane protein	NA	"The gene Nimrod C1 is referred to in FlyBase by the symbol Dmel\NimC1 (CG8942, FBgn0259896). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:13973158..13976769. It has the cytological map location 34E5. Protein features are: EGF-like domain; EGF-like, conserved site; EMI domain; Growth factor receptor cysteine-rich domain. Its molecular function is described by: . It is involved in the biological process described with: phagocytosis; defense response to bacterium. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: immune response defective; viable; short lived. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0036196	CG11658	0.778258085	0.046399662	0.999936032	NA	FBXO25;FBXO32	high;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG11658 (FBgn0036196). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (1 unique). Gene sequence location is 3L:11699496..11708553. It has the cytological map location 68D2. Protein features are: F-box domain. Its molecular function is described by: ubiquitin-protein transferase activity. It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. 15 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed within 12-24 hour embryonic stages, during late pupal stages.  "
FBgn0267443	CR45793	0.786270389	0.056934006	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR45793 (FBgn0267443). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3R:5263757..5264511. It has the cytological map location 82F8. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0031209	Ir21a	0.790364055	0.049080512	0.999936032	NA	GRID1	low	NA	transmembrane protein	NA	"The gene Ionotropic receptor 21a is referred to in FlyBase by the symbol Dmel\Ir21a (CG2657, FBgn0031209). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:21823..25155. It has the cytological map location 21A5-21B1. Protein features are: Ionotropic glutamate receptor. Its molecular function is described by: ligand-gated ion channel activity; ionotropic glutamate receptor activity. It is involved in the biological process described with: detection of chemical stimulus involved in sensory perception. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0262816	CG43187	0.80136712	0.054398513	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG43187 (FBgn0262816). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:16380516..16385765. It has the cytological map location 53C3-53C4. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported.
FBgn0034470	Obp56d	0.802428384	0.043637783	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Odorant-binding protein 56d is referred to in FlyBase by the symbol Dmel\Obp56d (CG11218, FBgn0034470). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:19702924..19703915. It has the cytological map location 56E2. Protein features are: Pheromone/general odorant binding protein. Its molecular function is described by: odorant binding. It is involved in the biological process described with: sensory perception of chemical stimulus; response to pheromone; sensory perception of smell; olfactory behavior. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in adult male stages.  "
FBgn0264987	CR44138	0.803256653	0.037368128	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44138 (FBgn0264987). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3R:13376903..13377395. It has the cytological map location 87E8. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0004644	hh	0.807132565	0.054750018	0.999936032	NA	SHH;DHH;IHH	high;moderate;moderate	NA	transmembrane protein	NA	"The gene hedgehog is referred to in FlyBase by the symbol Dmel\hh (CG4637, FBgn0004644). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:23128169..23141906. It has the cytological map location 94E1. Protein features are: Hedgehog protein; Hedgehog protein, Hint domain; Hedgehog signalling/DD-peptidase zinc-binding domain; Hedgehog, N-terminal signalling domain; Hedgehog/Intein (Hint) domain; Hint domain C-terminal; Hint domain N-terminal; Intein N-terminal splicing region. Its molecular function is described by: patched binding; morphogen activity; protein binding; peptidase activity; smoothened binding. It is involved in the biological process described with 67 unique terms, many of which group under: cell projection assembly; protein localization to cell surface; telencephalon development; ventral midline development; pigmentation; progression of morphogenetic furrow involved in compound eye morphogenesis; protein processing; germ cell attraction; periodic partitioning; neuron fate specification; anterior/posterior lineage restriction, imaginal disc; immune system process; cytoneme morphogenesis; neuron projection development; gonad development; analia development. 179 alleles are reported. The phenotypes of these alleles manifest in: embryonic midline of ventral nerve cord; trichome; larval abdominal segment 4; embryonic primordium of adult eye; cell component; abdominal segment 10; integumentary process; anterior commissure; anatomical space; basal apodeme of penis; embryonic brain; trunk mesoderm; penis; embryonic/larval ganglionic branch; internal sense organ; spectrosome; VUM neuron; embryonic small intestine. The phenotypic classes of alleles include: cell death defective; size defective; behavior defective; stress response defective; increased mortality; mitotic cell cycle defective; phenotype. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0000043	Act42A	0.807506642	0.034788462	0.999936032	POTEI	ACTB;ACTG1;POTEI;ACTC1;ACTG2;ACTA1;ACTA2;ACTBL2;POTEJ;POTEF;ACTRT3;ACTR1B;ACTR1A;POTEE	high;high;moderate;moderate;low;moderate;low;moderate;moderate;low;low;low;low;low	NA	NA	NA	"The gene Actin 42A is referred to in FlyBase by the symbol Dmel\Act42A (CG12051, FBgn0000043). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:6013910..6015689. It has the cytological map location 42A7. Protein features are: Actin family; Actin, conserved site; Actin/actin-like conserved site. Its molecular function is described by: structural constituent of cytoskeleton. It is involved in the biological process described with: mitotic cytokinesis; cytoskeleton organization; phagocytosis. 13 alleles are reported. The phenotypes of these alleles manifest in: wing sensillum; mesothoracic tergum; trichogen cell; chaeta; external sensory organ. The phenotypic classes of alleles include: partially lethal - majority die; some die during pupal stage; partially lethal; lethal; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of high expression.  Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0040850	CG15210	0.807609304	0.0355293	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15210 (FBgn0040850). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:10839230..10839895. It has the cytological map location 9F4-9F5. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0052279	Drsl2	0.808852656	0.027056378	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene Drosomycin-like 2 is referred to in FlyBase by the symbol Dmel\Drsl2 (CG32279, FBgn0052279). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:3314349..3314681. It has the cytological map location 63D1. Protein features are: Knottin, scorpion toxin-like. Its molecular function is described by: . It is involved in the biological process described with: defense response to protozoan; defense response to fungus. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of no expression detected.  Peak expression observed during early pupal stages.  "
FBgn0043005	prt	0.81038711	0.040075416	0.999936032	NA	SLC18A2;SLC18A1	moderate;low	NA	transmembrane protein	NA	"The gene portabella is referred to in FlyBase by the symbol Dmel\prt (CG10251, FBgn0043005). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:23696372..23699027. It has the cytological map location 95A7-95A8. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain. Its molecular function is described by: serotonin transmembrane transporter activity. It is involved in the biological process described with: male mating behavior; aminergic neurotransmitter loading into synaptic vesicle; olfactory learning; transmembrane transport. 12 alleles are reported. The phenotype of these alleles manifest in: sex comb tooth. The phenotypic classes of alleles include: learning defective; courtship behavior defective; fertile; mating defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.  "
FBgn0262563	CG43103	0.812113044	0.048187575	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG43103 (FBgn0262563). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:17139450..17139931. It has the cytological map location 54A1. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported.
FBgn0033294	Mal-A4	0.812553377	0.033544163	0.999936032	NA	SLC3A1;SLC3A2	moderate;low	NA	transmembrane protein	NA	"The gene Maltase A4 is referred to in FlyBase by the symbol Dmel\Mal-A4 (CG8693, FBgn0033294). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:8458815..8460884. It has the cytological map location 44D1. Protein features are: Glycoside hydrolase superfamily; Glycosyl hydrolase, family 13, catalytic domain. Its molecular function is described by: catalytic activity. It is involved in the biological process described with: carbohydrate metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during early larval stages.  "
FBgn0035359	CG1143	0.812690618	0.052181576	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG1143 (FBgn0035359). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:2645368..2647192. It has the cytological map location 62E8. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal - all die during P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during early larval stages.
FBgn0030421	CG3812	0.813280657	0.042303795	0.999936032	AGPAT1	AGPAT1;AGPAT2	high;moderate	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG3812 (FBgn0030421). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is X:12765266..12772851. It has the cytological map location 11B16-11C1. Protein features are: 1-acyl-sn-glycerol-3-phosphate acyltransferase; Phospholipid/glycerol acyltransferase. Its molecular function is described by: acylglycerol O-acyltransferase activity; 1-acylglycerol-3-phosphate O-acyltransferase activity. It is involved in the biological process described with: phospholipid biosynthetic process. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 00-12 hour embryonic stages.
FBgn0036806	Cyp12c1	0.817500303	0.033703519	0.999936032	NA	CYP24A1;CYP27C1;CYP27B1;CYP27A1;CYP11A1	high;moderate;low;low;moderate	NA	NA	NA	"The gene Cyp12c1 is referred to in FlyBase by the symbol Dmel\Cyp12c1 (CG4120, FBgn0036806). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:18684259..18686319. It has the cytological map location 75D6. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Its molecular function is described by: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; iron ion binding; heme binding. It is involved in the biological process described with: oxidation-reduction process. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; some die during pupal stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0262108	CR42861	0.822113424	0.046852535	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR42861 (FBgn0262108). It is a non_protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts. Gene sequence location is X:13744928..13745476. It has the cytological map location 12B4. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0039474	CG6283	0.82321719	0.032366398	0.999936032	NA	LPL	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6283 (FBgn0039474). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:27020238..27021378. It has the cytological map location 97D14. Protein features are: Alpha/Beta hydrolase fold; Lipase, N-terminal; Lipase/vitellogenin; Triacylglycerol lipase family; Vespid venom allergen phospholipase A1. Its molecular function is described by: phosphatidylcholine 1-acylhydrolase activity; lipase activity. It is involved in the biological process described with: lipid catabolic process. 5 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: flight defective; viable; visible; some die during pupal stage; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period, in adult male stages.  "
FBgn0035282	CNMa	0.82934961	0.041409459	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene CNMamide is referred to in FlyBase by the symbol Dmel\CNMa (CG13936, FBgn0035282). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:1850915..1855591. It has the cytological map location 62B7. Its molecular function is described by: neuropeptide hormone activity. It is involved in the biological process described with: G-protein coupled receptor signaling pathway. 3 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum. The phenotypic classes of alleles include: mating behavior defective; partially lethal - majority die; some die during pupal stage; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0015240	Hr96	0.830457635	0.034233381	0.999936032	NR1I2	NR1I2;PPARG;PPARA;PPARD;VDR;NR1H3;NR1I3	high;moderate;moderate;moderate;moderate;low;moderate	DNA-binding with transcription factor activity(zf-C4)	NA	NA	"The gene Hormone receptor-like in 96 is referred to in FlyBase by the symbol Dmel\Hr96 (CG11783, FBgn0015240). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:25025235..25029351. It has the cytological map location 96B16-96B17. Protein features are: Nuclear hormone receptor, ligand-binding domain; Zinc finger, NHR/GATA-type; Zinc finger, nuclear hormone receptor-type. Its molecular function is described by: RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding; RNA polymerase II regulatory region sequence-specific DNA binding; zinc ion binding; transcription factor activity, sequence-specific DNA binding. It is involved in the biological process described with: steroid hormone mediated signaling pathway; regulation of glycogen metabolic process; response to starvation; regulation of glucose metabolic process; regulation of transcription from RNA polymerase II promoter; triglyceride homeostasis; cholesterol homeostasis. 17 alleles are reported. The phenotypes of these alleles manifest in: adult fat body; lipid particle; adult midgut epithelium. The phenotypic classes of alleles include: chemical resistant; cell size defective; viable; phenotype; increased mortality; stress response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 hour embryonic stages, in adult female stages.  "
FBgn0051469	CG31469	0.836018444	0.041237955	0.999936032	NA	ACP1	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG31469 (FBgn0051469). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:13709159..13709939. It has the cytological map location 87F12. Protein features are: Phosphotyrosine protein phosphatase I superfamily; Protein-tyrosine phosphatase, low molecular weight. Its molecular function is described by: protein arginine phosphatase activity. It is involved in the biological process described with: peptidyl-N-phospho-arginine dephosphorylation. 6 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed within 00-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0260006	drd	0.836458654	0.046043511	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"The gene drop dead is referred to in FlyBase by the symbol Dmel\drd (CG33968, FBgn0260006). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:15125753..15137311. It has the cytological map location 13A12-13B1. Protein features are: Acyltransferase 3; Nose resistant-to-fluoxetine protein, N-terminal. Its molecular function is described by: transferase activity, transferring acyl groups other than amino-acyl groups. It is involved in the biological process described with: chitin-based cuticle development; defecation; digestive system process; digestion; oogenesis. 20 alleles are reported. The phenotypes of these alleles manifest in: adult brain; egg chamber; wing; abdomen; optic lobe; crop. The phenotypic classes of alleles include: increased mortality during development; phenotype; increased mortality; behavior defective; small body. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-18 embryonic stages.  "
FBgn0028940	Cyp28a5	0.843450909	0.031370692	0.999936032	NA	TBXAS1;CYP3A43;CYP3A4;CYP3A5;CYP3A7-CYP3A51P	moderate;low;low;low;low	NA	transmembrane protein	NA	"The gene Cyp28a5 is referred to in FlyBase by the symbol Dmel\Cyp28a5 (CG8864, FBgn0028940). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:13977302..13979569. It has the cytological map location 34E5. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group IV; Cytochrome P450, conserved site. Its molecular function is described by: monooxygenase activity; heme binding; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; electron carrier activity; oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during late larval stages.  "
FBgn0000256	capu	0.844519783	0.032858372	0.999936032	NA	FMN2;FMN1	high;moderate	NA	NA	NA	"The gene cappuccino is referred to in FlyBase by the symbol Dmel\capu (CG3399, FBgn0000256). It is a protein_coding_gene from Drosophila melanogaster. It has 9 annotated transcripts and 9 polypeptides (all unique). Gene sequence location is 2L:3872646..3902860. It has the cytological map location 24C8-24C9. Protein features are: Formin homology family, Cappuccino subfamily; Formin, FH2 domain. Its molecular function is described by: actin binding; microtubule binding. It is involved in the biological process described with: actin nucleation; pole plasm assembly; pole plasm oskar mRNA localization; oogenesis; pole plasm RNA localization; actin filament organization; actin filament-based process; chorion-containing eggshell formation. 47 alleles are reported. The phenotypes of these alleles manifest in: embryonic segment; supramolecular polymer; oocyte nucleus; intracellular part; acellular anatomical structure; intracellular non-membrane-bounded organelle; blastoderm embryo; external encapsulating structure; cell periphery; embryonic abdominal segment; pole plasm; dorsal appendage; nurse cell ring canal. The phenotypic classes of alleles include: sterile; lethal - all die before end of embryonic stage; phenotype; increased mortality. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed in adult male stages.  "
FBgn0264991	CG44142	0.844873015	0.021630197	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG44142 (FBgn0264991). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:13312855..13313188. It has the cytological map location 87E5. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported.
FBgn0036262	CG6910	0.846245948	0.043980425	0.999936032	MIOX	MIOX	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6910 (FBgn0036262). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 3L:12184984..12187860. It has the cytological map location 69A1. Protein features are: Inositol oxygenase. Its molecular function is described by: iron ion binding; inositol oxygenase activity. It is involved in the biological process described with: oxidation-reduction process; inositol catabolic process. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during late larval stages, in adult male stages.  "
FBgn0032809	CG13078	0.85693629	0.027726186	0.999936032	NA	CYB561D2;CYB561D1	moderate;high	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG13078 (FBgn0032809). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:19563930..19565158. It has the cytological map location 37F1. Protein features are: Cytochrome b561/ferric reductase transmembrane. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed during late larval stages.
FBgn0037151	CG7130	0.867664814	0.038639102	0.999936032	NA	DNAJB5;DNAJB4;DNAJB1;DNAJC22;DNAJB8	moderate;low;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7130 (FBgn0037151). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:22075056..22075756. It has the cytological map location 79B2. Protein features are: DnaJ domain; DnaJ domain, conserved site. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages.  "
FBgn0262357	CG43055	0.870813982	0.025143715	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG43055 (FBgn0262357). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:4411155..4411824. It has the cytological map location 24F1. Protein features are: C-type lectin fold; C-type lectin, conserved site; C-type lectin-like; C-type lectin-like/link domain. Its molecular function is described by: galactose binding. It is involved in the biological process described with: induction of bacterial agglutination. No alleles are reported."
FBgn0263762	CG43679	0.872778615	0.037702683	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG43679 (FBgn0263762). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:15050856..15051425. It has the cytological map location 71B2. Its molecular function is described by: . It is involved in the biological process described with: . No alleles are reported.
FBgn0052636	CR32636	0.875027958	0.037254698	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CR32636 (FBgn0052636).The gene has a gene model, but the supporting evidence is inconclusive. It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is X:13332374..13333857. It has the cytological map location 11E11. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported."
FBgn0033928	Arc2	0.876071443	0.029414446	0.999936032	NA	OARD1;ARC	low;low	NA	NA	NA	"The gene Arc2 is referred to in FlyBase by the symbol Dmel\Arc2 (CG13941, FBgn0033928). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:14361924..14362825. It has the cytological map location 50F6. Its molecular function is described by: . It is involved in the biological process described with: . 4 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: body color defective; visible; lethal - all die during P-stage; viable; partially lethal - majority die; some die during pupal stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 00-06 hour embryonic stages, at stages throughout the larval period, in adult female stages.  "
FBgn0063497	GstE3	0.878756752	0.02448047	0.999936032	NA	GSTT2B;GSTT1;GSTT2	moderate;moderate;moderate	NA	NA	NA	"The gene Glutathione S transferase E3 is referred to in FlyBase by the symbol Dmel\GstE3 (CG17524, FBgn0063497). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:18400713..18401467. It has the cytological map location 55C7. Protein features are: Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Thioredoxin-like fold. Its molecular function is described by: glutathione transferase activity. It is involved in the biological process described with: glutathione metabolic process. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages.  "
FBgn0035146	CG13893	0.87984648	0.028271476	0.999936032	SEC14L4	SEC14L3;SEC14L4;SEC14L2;SEC14L6;SEC14L1;MTFP1;SEC14L5	high;moderate;moderate;moderate;low;low;low	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13893 (FBgn0035146). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:599094..604008. It has the cytological map location 61C6. Protein features are: CRAL-TRIO lipid binding domain; CRAL/TRIO, N-terminal domain; Cellular retinaldehyde binding/alpha-tocopherol transport; GOLD domain. Its molecular function is described by: transporter activity. It is involved in the biological process described with: transport. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable; partially lethal. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed during late larval stages.  "
FBgn0033978	Cyp6a23	0.883063793	0.023244568	0.999936032	TBXAS1	TBXAS1;CYP3A4;CYP3A43;CYP3A5;CYP3A7-CYP3A51P;CYP3A7	moderate;moderate;moderate;moderate;low;low	NA	transmembrane protein	NA	"The gene Cyp6a23 is referred to in FlyBase by the symbol Dmel\Cyp6a23 (CG10242, FBgn0033978). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:14875829..14877654. It has the cytological map location 51D1. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site. Its molecular function is described by: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; iron ion binding; heme binding; oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, during late larval stages.  "
FBgn0030737	CG9914	0.883079576	0.024434801	0.999936032	CRYL1	CRYL1	high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9914 (FBgn0030737). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is X:16306912..16308667. It has the cytological map location 14B9. Protein features are: 3-hydroxyacyl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase, C-terminal; 3-hydroxyacyl-CoA dehydrogenase, NAD binding; 3-hydroxyacyl-CoA dehydrogenase, conserved site; 6-phosphogluconate dehydrogenase C-terminal domain-like; 6-phosphogluconate dehydrogenase, domain 2; NAD(P)-binding domain. Its molecular function is described by: 3-hydroxyacyl-CoA dehydrogenase activity; NAD+ binding. It is involved in the biological process described with: fatty acid metabolic process; oxidation-reduction process. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0032603	CG17928	0.886303197	0.031773471	0.999936032	NA	FADS1;FADS2;FADS3	high;high;high	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17928 (FBgn0032603). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:16791568..16793444. It has the cytological map location 36B1. Protein features are: Cytochrome b5-like heme/steroid binding domain; Fatty acid desaturase; Fatty acid desaturase domain. Its molecular function is described by: oxidoreductase activity. It is involved in the biological process described with: lateral inhibition; lipid metabolic process. 11 alleles are reported. The phenotype of these alleles manifest in: chaeta. The phenotypic classes of alleles include: partially lethal; some die during pupal stage; visible; lethal - all die during P-stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0038257	smp-30	0.891479837	0.023677212	0.999936032	RGN	RGN	high	NA	NA	NA	"The gene Senescence marker protein-30 is referred to in FlyBase by the symbol Dmel\smp-30 (CG7390, FBgn0038257). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 3R:14745901..14751246. It has the cytological map location 88D2. Protein features are: SMP-30/Gluconolactonase/LRE-like region; Senescence marker protein-30 (SMP-30); Six-bladed beta-propeller, TolB-like. Its molecular function is described by: gluconolactonase activity; calcium ion binding. It is involved in the biological process described with: negative regulation of imaginal disc-derived wing size; regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis; L-ascorbic acid biosynthetic process; cold acclimation. 7 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: size defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during early larval stages.  "
FBgn0058469	CR40469	0.892558802	0.022589001	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR40469 (FBgn0058469). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is X:122493..122706. It has the cytological map location 1A1. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0000078	Amy-d	0.892851985	0.021871723	0.999936032	NA	AMY2B;AMY1C;AMY1B;AMY2A;AMY1A	moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"The gene Amylase distal is referred to in FlyBase by the symbol Dmel\Amy-d (CG17876, FBgn0000078). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:17124764..17126369. It has the cytological map location 53F12. Protein features are: Alpha amylase; Alpha-amylase, C-terminal domain; Alpha-amylase/branching enzyme, C-terminal all beta; Glycoside hydrolase superfamily; Glycosyl hydrolase, family 13, catalytic domain. Its molecular function is described by: calcium ion binding; cation binding; alpha-amylase activity; catalytic activity. It is involved in the biological process described with: carbohydrate metabolic process. 20 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: electrophoretic variant. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during late larval stages, in adult male stages.  "
FBgn0002716	mei-W68	0.897701983	0.027921091	0.999936032	NA	SPO11	high	NA	NA	NA	"The gene meiotic W68 is referred to in FlyBase by the symbol Dmel\mei-W68 (CG7753, FBgn0002716). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:19456170..19459523. It has the cytological map location 56D9. Protein features are: DNA topoisomerase VI, subunit A; Spo11/DNA topoisomerase VI subunit A; Spo11/DNA topoisomerase VI, subunit A, N-terminal; Topoisomerase 6 subunit A/Spo11, TOPRIM domain; Winged helix-turn-helix DNA-binding domain. Its molecular function is described by: DNA binding; DNA topoisomerase type II (ATP-hydrolyzing) activity; ATP binding; endodeoxyribonuclease activity, producing 3'-phosphomonoesters. It is involved in the biological process described with: early meiotic recombination nodule assembly; DNA catabolic process, endonucleolytic; meiotic DNA double-strand break formation; DNA topological change; late meiotic recombination nodule assembly; reciprocal meiotic recombination; karyosome formation; meiotic DNA double-strand break processing; oogenesis. 20 alleles are reported. The phenotypes of these alleles manifest in: early recombination nodule; germarium; late recombination nodule. The phenotypic classes of alleles include: lethal; meiotic cell cycle defective; viable; wild-type. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of very low expression.  Peak expression observed within 06-12 hour embryonic stages.  "
FBgn0033668	exp	0.900324962	0.015855241	0.999936032	NA	SMAD2	low	Maybe TF	NA	NA	"The gene expansion is referred to in FlyBase by the symbol Dmel\exp (CG13188, FBgn0033668). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (all unique). Gene sequence location is 2R:11939557..11967435. It has the cytological map location 48D3-48D5. Protein features are: SMAD domain, Dwarfin-type; SMAD domain-like; SMAD/FHA domain; WD40/YVTN repeat-like-containing domain. Its molecular function is unknown. It is involved in the biological process described with: transmembrane receptor protein tyrosine phosphatase signaling pathway; regulation of transcription, DNA-templated; chitin biosynthetic process; trachea morphogenesis; cuticle chitin biosynthetic process. 11 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval dorsal branch; embryonic/larval ganglionic branch; cephalopharyngeal skeleton; embryonic/larval trachea; embryonic/larval lateral trunk; embryonic/larval mouth. The phenotypic classes of alleles include: lethal; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the pupal period.  "
FBgn0004374	neb	0.90274838	0.030215827	0.999936032	NA	KIF14	high	NA	NA	NA	"The gene nebbish is referred to in FlyBase by the symbol Dmel\neb (CG10718, FBgn0004374). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:20075757..20089698. It has the cytological map location 38B3-38B5. Protein features are: Forkhead-associated (FHA) domain; Kinesin motor domain; Kinesin motor domain, conserved site; P-loop containing nucleoside triphosphate hydrolase; SMAD/FHA domain. Its molecular function is described by: protein phosphatase 1 binding; ATP binding; ATP-dependent microtubule motor activity, plus-end-directed; microtubule motor activity; microtubule binding; chromatin binding. It is involved in the biological process described with: meiotic cell cycle; mitotic chromosome condensation; microtubule-based movement; mitotic cell cycle, embryonic; chromosome segregation; oogenesis; ovarian follicle cell development; mitotic sister chromatid segregation; regulation of cell cycle. 52 alleles are reported. The phenotypes of these alleles manifest in: internal sense organ; central nervous system; embryonic/larval integumentary system; dorsal closure embryo; larva; embryonic segment; egg; appendage; sensory neuron; acellular anatomical structure; embryonic/larval brain; blastoderm embryo; male organism; centrosome. The phenotypic classes of alleles include: cell cycle defective; increased mortality; phenotype; behavior defective; wild-type. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-12 hour embryonic stages, in adult male stages.  "
FBgn0263106	DnaJ-1	0.90575573	0.029478227	0.999936032	NA	DNAJB4;DNAJB1;DNAJB5;DNAJB13;DNAJC22	high;moderate;moderate;moderate;low	NA	NA	NA	"The gene DnaJ-like-1 is referred to in FlyBase by the symbol Dmel\DnaJ-1 (CG10578, FBgn0263106). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:5750029..5752189. It has the cytological map location 64E5. Protein features are: Chaperone DnaJ, C-terminal; DnaJ domain; DnaJ domain, conserved site; HSP40/DnaJ peptide-binding. Its molecular function is described by: unfolded protein binding. It is involved in the biological process described with: protein folding; response to heat. 29 alleles are reported. The phenotypes of these alleles manifest in: segment of leg; leg. The phenotypic class of alleles includes: viable."
FBgn0051741	CG31741	0.914776008	0.028890389	0.999936032	NA	SCARB1;SCARB2;CD36	moderate;low;low	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG31741 (FBgn0051741). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:18084256..18086714. It has the cytological map location 36E3. Protein features are: CD36 family. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. The phenotype of these alleles manifest in: hemocyte. The phenotypic classes of alleles include: short lived; viable; immune response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed during late larval stages.
FBgn0034200	Gbp2	0.915157355	0.023923803	0.999936032	NA	SAT2;QRICH2;SATL1	low;low;low	NA	NA	NA	"The gene Growth-blocking peptide 2 is referred to in FlyBase by the symbol Dmel\Gbp2 (CG11395, FBgn0034200). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:17137240..17139595. It has the cytological map location 54A1. Protein features are: Diamine acetyltransferase 2. Its molecular function is described by: cytokine activity; N-acetyltransferase activity. It is involved in the biological process described with: signal transduction. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: increased mortality during development; phenotype; increased mortality; lethal - all die before end of P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed at stages throughout the larval period.  "
FBgn0039323	CG10559	0.916186762	0.02478318	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10559 (FBgn0039323). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:25314494..25316116. It has the cytological map location 96D1. Protein features are: CHK kinase-like; Protein kinase-like domain; Protein of unknown function DUF227. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.  "
FBgn0261387	CG17528	0.918580088	0.022685825	0.999936032	NA	DCLK1;DCLK2;DCX;DCLK3;CAMK4	high;moderate;moderate;moderate;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17528 (FBgn0261387). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:4815426..4824319. It has the cytological map location 41C2. Protein features are: Calcium/calmodulin-dependent/calcium-dependent protein kinase; Doublecortin domain; Protein kinase domain; Protein kinase, ATP binding site; Protein kinase-like domain; Serine/threonine-protein kinase, active site. Its molecular function is described by: microtubule binding; protein serine/threonine kinase activity; calmodulin-dependent protein kinase activity; calcium-dependent protein serine/threonine kinase activity; calmodulin binding; ATP binding. It is involved in the biological process described with: peptidyl-serine phosphorylation; protein autophosphorylation; microtubule-based process; intracellular signal transduction; protein phosphorylation. 5 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: female semi-sterile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of moderate expression.  Peak expression observed within 00-18 hour embryonic stages.  "
FBgn0034289	CG10910	0.92037568	0.01992567	0.999936032	NA	MAGED4B;MAGED2;MAGED4;TRO;MAGED1;CDA	low;low;low;low;low;low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG10910 (FBgn0034289). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:18020268..18022406. It has the cytological map location 55B1. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the larval period.
FBgn0050090	CG30090	0.93462719	0.020865247	0.999936032	NA	CTSG;GZMB;GZMH;CMA1	low;low;low;low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG30090 (FBgn0050090). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:15689826..15691014. It has the cytological map location 52C1. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during late larval stages.  "
FBgn0003358	Jon99Ci	0.941416183	0.016827779	0.999936032	NA	PROC	low	NA	NA	NA	"The gene Jonah 99Ci is referred to in FlyBase by the symbol Dmel\Jon99Ci (CG31039, FBgn0003358). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:29925226..29926189. It has the cytological map location 99C7. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity; endopeptidase activity. It is involved in the biological process described with: proteolysis. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0030332	CG9360	0.942034224	0.023017699	0.999936032	NA	DHRS11	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG9360 (FBgn0030332). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:11763474..11764590. It has the cytological map location 10E2. Protein features are: NAD(P)-binding domain; Short-chain dehydrogenase/reductase SDR. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. The phenotypic class of allele includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.  "
FBgn0031654	Jon25Bii	0.944919143	0.016651919	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Jonah 25Bii is referred to in FlyBase by the symbol Dmel\Jon25Bii (CG8869, FBgn0031654). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:4952243..4953136. It has the cytological map location 25B4. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis. 4 alleles are reported. The phenotypes of these alleles manifest in: trichogen cell; mesothoracic tergum; embryonic/larval neuroblast. The phenotypic classes of alleles include: increased mortality; increased mortality during development; flight defective; phenotype; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of no expression detected.  Peak expression observed at stages throughout the larval period.  "
FBgn0039094	CG10184	0.945830817	0.021294953	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10184 (FBgn0039094). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:23602507..23605495. It has the cytological map location 95A4. Protein features are: Aromatic amino acid beta-eliminating lyase/threonine aldolase; Pyridoxal phosphate-dependent transferase; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; Pyridoxal phosphate-dependent transferase, subdomain 2; Threonine aldolase. Its molecular function is described by: L-allo-threonine aldolase activity. It is involved in the biological process described with: glycine biosynthetic process; threonine catabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during early larval stages.  "
FBgn0038832	CG15695	0.947433795	0.019518086	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15695 (FBgn0038832). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:20842140..20844981. It has the cytological map location 93A2. Protein features are: Alkaline phosphatase-like, alpha/beta/alpha; Alkaline-phosphatase-like, core domain; Protein of unknown function DUF229. Its molecular function is described by: catalytic activity. It is involved in the biological process described with: metabolic process; multicellular organism reproduction. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0039475	CG6277	0.952415201	0.01602866	0.999936032	NA	LIPH;LIPG	high;high	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG6277 (FBgn0039475). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:27022071..27023217. It has the cytological map location 97D14. Protein features are: Alpha/Beta hydrolase fold; Lipase, N-terminal; Lipase/vitellogenin; Triacylglycerol lipase family; Vespid venom allergen phospholipase A1. Its molecular function is described by: lipase activity; phosphatidylcholine 1-acylhydrolase activity. It is involved in the biological process described with: lipid catabolic process. 5 alleles are reported. The phenotypes of these alleles manifest in: ganglion mother cell; embryonic/larval neuroblast; indirect flight muscle; sarcomere; myofibril; trichogen cell; Z disc. The phenotypic classes of alleles include: neuroanatomy defective; visible; viable; lethal; flightless. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of no expression detected.  Peak expression observed during late larval stages, in adult male stages.  "
FBgn0261575	tobi	0.95256178	0.015829913	0.999936032	NA	KIAA1161	high	NA	NA	NA	"The gene target of brain insulin is referred to in FlyBase by the symbol Dmel\tobi (CG11909, FBgn0261575). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:25344761..25346921. It has the cytological map location 96D2. Protein features are: Glycoside hydrolase family 31; Glycoside hydrolase superfamily. Its molecular function is described by: hydrolase activity, hydrolyzing O-glycosyl compounds. It is involved in the biological process described with: carbohydrate metabolic process. 8 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; lethal - all die before end of embryonic stage; short lived; lethal; some die during embryonic stage; small body. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during early pupal stages, in stages of adults of both sexes.  "
FBgn0053192	MtnD	0.957467838	0.022016007	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Metallothionein D is referred to in FlyBase by the symbol Dmel\MtnD (CG33192, FBgn0053192). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:20534962..20535301. It has the cytological map location 92F1. Protein features are: Metallothionein, family 5, Diptera. Its molecular function is described by: metal ion binding. It is involved in the biological process described with: response to metal ion; response to copper ion; metal ion homeostasis. 8 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during early larval stages, during early pupal stages.  "
FBgn0020506	Amyrel	0.965049419	0.016545326	0.999936032	NA	AMY1C;AMY1B;AMY2B;AMY2A;AMY1A	moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"The gene Amyrel is referred to in FlyBase by the symbol Dmel\Amyrel (CG8221, FBgn0020506). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:16651095..16652699. It has the cytological map location 53C14. Protein features are: Alpha amylase; Alpha-amylase, C-terminal domain; Alpha-amylase/branching enzyme, C-terminal all beta; Glycoside hydrolase superfamily; Glycosyl hydrolase, family 13, catalytic domain. Its molecular function is described by: cation binding; catalytic activity. It is involved in the biological process described with: carbohydrate metabolic process. 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed during early larval stages.  "
FBgn0063368	Gpb5	0.96596099	0.017224051	0.999936032	NA	GPHB5;FSHB;CGB8;LHB;TSHB;CGB2	high;moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"The gene Glycoprotein hormone beta 5 is referred to in FlyBase by the symbol Dmel\Gpb5 (CG40041, FBgn0063368). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (all unique). Gene sequence location is 2L:23311700..23312464. Protein features are: Cystine-knot cytokine; Glycoprotein hormone subunit beta; Gonadotropin, beta subunit. Its molecular function is described by: hormone activity; protein heterodimerization activity; G-protein coupled receptor binding. It is involved in the biological process described with: G-protein coupled receptor signaling pathway; hormone-mediated signaling pathway; cell-cell signaling. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: partially lethal - majority die. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of very low expression.  Peak expression observed within 06-24 hour embryonic stages, during early larval stages, during late pupal stages.  "
FBgn0259994	CG42492	0.967976265	0.021256871	0.999936032	NA	OTOP2;OTOP1;OTOP3	high;high;moderate	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG42492 (FBgn0259994). It is a protein_coding_gene from Drosophila melanogaster. It has 6 annotated transcripts and 6 polypeptides (all unique). Gene sequence location is X:5625676..5648487. It has the cytological map location 5A9. Protein features are: Otopetrin. Its molecular function is unknown. The biological processes in which it is involved are not known. 12 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of very low expression.  Peak expression observed during late pupal stages.
FBgn0036951	CG7017	0.975127573	0.017144566	0.999936032	NA	MATN2	low	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG7017 (FBgn0036951). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:20210292..20212122. It has the cytological map location 77A2. Protein features are: Chitin binding domain. Its molecular function is described by: chitin binding. It is involved in the biological process described with: chitin metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: partially lethal; some die during pupal stage; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages.  "
FBgn0043783	CG32444	0.9791139	0.01426244	0.999936032	NA	GALM	moderate	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG32444 (FBgn0043783). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:21636947..21639060. It has the cytological map location 78E1-78E2. Protein features are: Aldose 1-/Glucose-6-phosphate 1-epimerase; Aldose 1-epimerase; Galactose mutarotase-like domain; Glycoside hydrolase-type carbohydrate-binding. Its molecular function is described by: carbohydrate binding; aldose 1-epimerase activity. It is involved in the biological process described with: glucose metabolic process; galactose catabolic process via UDP-galactose. 6 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: fertile; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed in adult male stages.
FBgn0033999	CG8093	0.984696069	0.013350669	0.999936032	NA	LIPM;LIPK;LIPF;LIPA;LIPJ;LIPN	high;moderate;moderate;moderate;moderate;moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG8093 (FBgn0033999). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:15214060..15215686. It has the cytological map location 51E7. Protein features are: Alpha/Beta hydrolase fold; Lipase, eukaryotic; Partial AB-hydrolase lipase domain. Its molecular function is described by: hydrolase activity, acting on ester bonds; lipase activity. It is involved in the biological process described with: multicellular organism reproduction; lipid metabolic process. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during late larval stages, in stages of adults of both sexes.  "
FBgn0010043	GstD7	0.988598706	0.018328688	0.999936032	NA	GSTT2B;GSTT1;MARS;VARS;GSTT2;EEF1G;EEF1E1	low;low;low;low;low;low;low	NA	NA	NA	"The gene Glutathione S transferase D7 is referred to in FlyBase by the symbol Dmel\GstD7 (CG4371, FBgn0010043). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:12378500..12379255. It has the cytological map location 87B8. Protein features are: Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Thioredoxin-like fold. Its molecular function is described by: glutathione transferase activity. It is involved in the biological process described with: glutathione metabolic process. 3 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: flightless; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.  Peak expression observed during early larval stages.  "
FBgn0039473	CG17191	0.99858346	0.016732739	0.999936032	NA	PNLIPRP1	moderate	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17191 (FBgn0039473). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:27018608..27019751. It has the cytological map location 97D14. Protein features are: Alpha/Beta hydrolase fold; Lipase, N-terminal; Lipase/vitellogenin; Triacylglycerol lipase family; Vespid venom allergen phospholipase A1. Its molecular function is described by: phosphatidylcholine 1-acylhydrolase activity; lipase activity. It is involved in the biological process described with: lipid catabolic process. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during early larval stages.  "
FBgn0000003	7SLRNA:CR32864	1.000991004	0.015433873	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Signal recognition particle 7SL RNA CR32864 is referred to in FlyBase by the symbol Dmel\7SLRNA:CR32864 (CR32864, FBgn0000003). It is a non_protein_coding_gene from Drosophila melanogaster. It has one annotated transcript. Gene sequence location is 3R:6822498..6822796. It has the cytological map location 84A5. Its molecular function is unknown. It is involved in the biological process described with: SRP-dependent cotranslational protein targeting to membrane. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of moderate expression.  Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes.  CAVEAT: These RNA-Seq temporal profiles depend upon RNA-Seq reads that are uniquely placed in the genome.  For this reason, genes such as histones, Stellates and many classes of RNA genes that are present in multiple exact or near exact copies in the genome, expression levels may be reported as much lower than their true values."
FBgn0033301	CG12780	1.001765592	0.01236527	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG12780 (FBgn0033301). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:8551859..8552290. It has the cytological map location 44D2. Protein features are: Beta-1,3-glucan-binding protein, N-terminal. Its molecular function is described by: carbohydrate binding. It is involved in the biological process described with: defense response to virus; detection of biotic stimulus. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during late larval stages, during late pupal stages, in adult male stages.  "
FBgn0038412	Zip89B	1.013039504	0.015273469	0.999936032	NA	SLC39A2;SLC39A1;SLC39A3	high;high;moderate	NA	transmembrane protein	NA	"The gene Zinc/iron regulated transporter-related protein 89B is referred to in FlyBase by the symbol Dmel\Zip89B (CG6898, FBgn0038412). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:16305758..16308700. It has the cytological map location 89B12. Protein features are: Zinc/iron permease. Its molecular function is described by: zinc ion transmembrane transporter activity. It is involved in the biological process described with: zinc II ion transmembrane transport; detoxification of zinc ion. 8 alleles are reported. The phenotype of these alleles manifest in: eye. The phenotypic classes of alleles include: developmental rate defective; short lived; visible; viable; long lived; chemical resistant. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 12-18 embryonic stages, during late larval stages, at stages throughout the pupal period.  "
FBgn0032067	LManIV	1.016504968	0.014368977	0.999936032	NA	MAN2B1;MAN2B2	moderate;low	NA	NA	NA	"The gene Lysosomal ‘±-mannosidase IV is referred to in FlyBase by the symbol Dmel\LManIV (CG9465, FBgn0032067). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:8769159..8772344. It has the cytological map location 29F1. Protein features are: Galactose mutarotase-like domain; Glycoside hydrolase 38/57, N-terminal domain; Glycoside hydrolase families 57/38, central domain; Glycoside hydrolase family 38, N-terminal domain; Glycoside hydrolase family 38, central domain; Glycoside hydrolase/deacetylase, beta/alpha-barrel; Glycosyl hydrolase family 38, C-terminal. Its molecular function is described by: carbohydrate binding; alpha-mannosidase activity. It is involved in the biological process described with: protein deglycosylation; mannose metabolic process. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed during late larval stages.  "
FBgn0085345	CG34316	1.023505872	0.014545745	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG34316 (FBgn0085345). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:15230585..15231686. It has the cytological map location 88E3. Protein features are: Haemolymph juvenile hormone binding. Its molecular function is unknown. It is involved in the biological process described with: multicellular organism reproduction; circadian rhythm. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.  Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during late pupal stages, in adult female stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0051955	CG31955	1.031508245	0.014068574	0.999936032	NA	CHTF18	low	Maybe TF	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG31955 (FBgn0051955). It is a protein_coding_gene from Drosophila melanogaster. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is 2L:3711881..3713105. It has the cytological map location 24C1. Its molecular function is described by: . The biological processes in which it is involved are not known. 8 alleles are reported. The phenotype of these alleles manifest in: wing. The phenotypic classes of alleles include: pain response defective; viable; visible. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during early pupal stages.
FBgn0010387	Dbi	1.036444677	0.009953978	0.999936032	NA	DBI;ACBD7;ACBD4;ACBD6;ACBD5	moderate;moderate;low;low;low	NA	NA	NA	"The gene Diazepam-binding inhibitor is referred to in FlyBase by the symbol Dmel\Dbi (CG8627, FBgn0010387). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:7131863..7133463. It has the cytological map location 65E4. Protein features are: Acyl-CoA-binding protein, ACBP; Acyl-CoA-binding protein, ACBP, conserved site; FERM/acyl-CoA-binding protein, 3-helical bundle. Its molecular function is described by: fatty-acyl-CoA binding. It is involved in the biological process described with: cellular acyl-CoA homeostasis. 2 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of very low expression.  Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.  "
FBgn0032086	CG17906	1.037484979	0.013495594	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG17906 (FBgn0032086). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:8994391..8995617. It has the cytological map location 29F7. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of extremely low expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, during early larval stages.  "
FBgn0031033	CG14219	1.038001614	0.011088834	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG14219 (FBgn0031033). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:19587348..19590170. It has the cytological map location 18D3. Protein features are: Acyltransferase 3; Nose resistant-to-fluoxetine protein, N-terminal. Its molecular function is described by: transferase activity, transferring acyl groups other than amino-acyl groups. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0261675	Npc1b	1.043269565	0.009952759	0.999936032	NA	NPC1;NPC1L1	moderate;moderate	NA	transmembrane protein	NA	"The gene Niemann-Pick type C-1b is referred to in FlyBase by the symbol Dmel\Npc1b (CG12092, FBgn0261675). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is X:20934869..20939503. It has the cytological map location 19E4. Protein features are: Niemann-Pick C1, N-terminal; Protein patched/dispatched; Sterol-sensing domain. Its molecular function is unknown. It is involved in the biological process described with: peripheral nervous system development; dorsal closure; intestinal cholesterol absorption; central nervous system development. 38 alleles are reported. The phenotypes of these alleles manifest in: embryonic/first instar larval cuticle; embryo; embryonic head; trichogen cell. The phenotypic classes of alleles include: phenotype; increased mortality during development; increased mortality; lethal - all die before end of P-stage. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.  Peak expression observed during early larval stages.  "
FBgn0040729	CG15126	1.046477808	0.011013391	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG15126 (FBgn0040729). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:19690798..19691078. It has the cytological map location 56E2. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of no expression detected.  Peak expression observed within 18-24 hour embryonic stages.
FBgn0037850	CG14695	1.04747222	0.011912163	0.999936032	NA	ERP27;DNAJC10;TXNDC16;PDILT;PDIA6;TXNDC5;PDIA5	low;low;low;low;low;low;low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG14695 (FBgn0037850). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:10878204..10879319. It has the cytological map location 86C7. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.  Peak expression observed in adult male stages.
FBgn0036320	CG10943	1.048910598	0.010201118	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG10943 (FBgn0036320). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3L:12861717..12862920. It has the cytological map location 69E6. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed during late larval stages, during early pupal stages, in adult female stages.  "
FBgn0001223	Hsp22	1.053845183	0.012106319	0.999936032	NA	HSPB8;HSPB1;HSPB2;HSPB3;HSPB7;HSPB6;CRYAB;CRYAA	high;low;low;moderate;moderate;low;low;low	NA	NA	NA	"The gene Heat shock protein 22 is referred to in FlyBase by the symbol Dmel\Hsp22 (CG4460, FBgn0001223). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3L:9372931..9374964. It has the cytological map location 67B2. Protein features are: Alpha crystallin/Heat shock protein; Alpha crystallin/Hsp20 domain; HSP20-like chaperone; Small heat shock protein HSP20. Its molecular function is described by: unfolded protein binding; identical protein binding. It is involved in the biological process described with: chaperone-mediated protein folding; response to heat; determination of adult lifespan; response to oxidative stress. 13 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: phenotype; temperature response defective; increased mortality; stress response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed during late pupal stages.  This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.  The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.  "
FBgn0085227	CG34198	1.053924779	0.009258388	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG34198 (FBgn0085227). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:19682446..19682977. It has the cytological map location 56E1. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.  Peak expression observed within 18-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult female stages.  "
FBgn0063493	GstE7	1.05697727	0.009105854	0.999936032	NA	GSTT2B;GSTT1;GSTT2	moderate;moderate;moderate	NA	NA	NA	"The gene Glutathione S transferase E7 is referred to in FlyBase by the symbol Dmel\GstE7 (CG17531, FBgn0063493). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:18406924..18407688. It has the cytological map location 55C7. Protein features are: Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Thioredoxin-like fold. Its molecular function is described by: glutathione transferase activity. It is involved in the biological process described with: glutathione metabolic process. 7 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; fertile. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of very high expression to a trough of low expression.  Peak expression observed within 18-24 hour embryonic stages.  "
FBgn0053510	CG33510	1.062315774	0.011079075	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG33510 (FBgn0053510). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:21082643..21084326. It has the cytological map location 39A1. Protein features are: CHK kinase-like; Protein kinase-like domain; Protein of unknown function DUF227. Its molecular function is described by: . It is involved in the biological process described with: . 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed during early larval stages.
FBgn0039151	CG13607	1.074314534	0.009862971	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG13607 (FBgn0039151). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:24114043..24116322. It has the cytological map location 95E1. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. The phenotypic class of allele includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of extremely low expression.  Peak expression observed during late larval stages, during early pupal stages.  "
FBgn0262146	MtnE	1.076514177	0.00985437	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Metallothionein E is referred to in FlyBase by the symbol Dmel\MtnE (CG42872, FBgn0262146). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:20534021..20534704. It has the cytological map location 92F1. Protein features are: Metallothionein, family 5, Diptera. Its molecular function is described by: metal ion binding. It is involved in the biological process described with: detoxification of cadmium ion; response to copper ion; response to silver ion; response to zinc ion; response to mercury ion. 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available."
FBgn0051148	Gba1a	1.089825555	0.007462953	0.999936032	NA	GBA	high	NA	NA	NA	"The gene Glucocerebrosidase 1a is referred to in FlyBase by the symbol Dmel\Gba1a (CG31148, FBgn0051148). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:23700621..23702605. It has the cytological map location 95A8. Protein features are: Glycoside hydrolase family 30; Glycoside hydrolase superfamily; Glycosyl hydrolase family 30, TIM-barrel domain; Glycosyl hydrolase family 30, beta sandwich domain. Its molecular function is described by: glucosylceramidase activity. It is involved in the biological process described with: cellular response to unfolded protein; glucosylceramide catabolic process; adult locomotory behavior; determination of adult lifespan; neuron cellular homeostasis; memory. 5 alleles are reported. The phenotype of these alleles manifest in: mesothoracic tergum. The phenotypic classes of alleles include: long lived; sleep defective; visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed during late larval stages.  "
FBgn0063492	GstE8	1.094023807	0.007689614	0.999936032	NA	GSTT2B;GSTT1;GSTT2	moderate;moderate;moderate	NA	NA	NA	"The gene Glutathione S transferase E8 is referred to in FlyBase by the symbol Dmel\GstE8 (CG17533, FBgn0063492). It is a protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:18407834..18408955. It has the cytological map location 55C7-55C8. Protein features are: Glutathione S-transferase, C-terminal; Glutathione S-transferase, C-terminal-like; Glutathione S-transferase, N-terminal; Thioredoxin-like fold. Its molecular function is described by: glutathione transferase activity. It is involved in the biological process described with: glutathione metabolic process. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of low expression.  Peak expression observed within 00-06 and 18-24 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes.  "
FBgn0038098	CG7381	1.096320751	0.007272281	0.999936032	NA	NA	NA	NA	transmembrane protein	NA	This gene is referred to in FlyBase by the symbol Dmel\CG7381 (FBgn0038098). It is a protein_coding_gene from Drosophila melanogaster. It has 5 annotated transcripts and 5 polypeptides (3 unique). Gene sequence location is 3R:12967775..12977471. It has the cytological map location 87D5-87D6. Protein features are: EB domain. Its molecular function is described by: . It is involved in the biological process described with: . 12 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.  Peak expression observed during early larval stages.
FBgn0265081	CR44192	1.097420213	0.007994578	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CR44192 (FBgn0265081). It is a non_protein_coding_gene from Drosophila melanogaster. It has 2 annotated transcripts. Gene sequence location is 3R:10052846..10054298. It has the cytological map location 85F8. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported.
FBgn0033926	Arc1	1.104704494	0.006664151	0.999936032	NA	OARD1;ARC	low;low	NA	NA	NA	"The gene Activity-regulated cytoskeleton associated protein 1 is referred to in FlyBase by the symbol Dmel\Arc1 (CG12505, FBgn0033926). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:14357927..14360297. It has the cytological map location 50F6. Protein features are: Zinc finger, CCHC-type. Its molecular function is described by: nucleic acid binding; zinc ion binding. It is involved in the biological process described with: muscle system process; behavioral response to starvation. 9 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: locomotor behavior defective; stress response defective; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of high expression to a trough of low expression.  Peak expression observed during late larval stages, during early pupal stages, in adult male stages.  "
FBgn0040958	Peritrophin-15b	1.117572257	0.007350122	0.999936032	NA	NA	NA	NA	NA	NA	"The gene Peritrophin-15b is referred to in FlyBase by the symbol Dmel\Peritrophin-15b (CG31893, FBgn0040958). It is a protein_coding_gene from Drosophila melanogaster. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 2L:8394446..8394940. It has the cytological map location 29C1. Protein features are: Chitin binding domain. Its molecular function is described by: chitin binding. It is involved in the biological process described with: chitin metabolic process. 3 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; pain response defective. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of no expression detected.  Peak expression observed during late larval stages.  "
FBgn0028853	CG15263	1.11777143	0.006595383	0.999936032	NA	NA	NA	NA	NA	NA	"This gene is referred to in FlyBase by the symbol Dmel\CG15263 (FBgn0028853). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:15285000..15286047. It has the cytological map location 35D1. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. The phenotypic class of alleles includes: viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of low expression to a trough of no expression detected.  Peak expression observed during late pupal stages, in stages of adults of both sexes.  "
FBgn0054040	CG34040	1.121715456	0.006271092	0.999936032	NA	LYNX1;LY6D	low;low	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG34040 (FBgn0054040). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2R:21832501..21833551. It has the cytological map location 58A2. Protein features are: Domain of unknown function DUF753. Its molecular function is described by: . It is involved in the biological process described with: . 2 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.  Peak expression observed in adult male stages.
FBgn0020906	Jon25Bi	1.128707957	0.005826343	0.999936032	NA	KLK3	low	NA	NA	NA	"The gene Jonah 25Bi is referred to in FlyBase by the symbol Dmel\Jon25Bi (CG8867, FBgn0020906). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:4954279..4955144. It has the cytological map location 25B4. Protein features are: Peptidase S1, PA clan; Peptidase S1A, chymotrypsin family; Serine proteases, trypsin domain; Serine proteases, trypsin family, histidine active site; Serine proteases, trypsin family, serine active site. Its molecular function is described by: serine-type endopeptidase activity; endopeptidase activity. It is involved in the biological process described with: proteolysis. 5 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; viable. Summary of modENCODE Temporal Expression Profile:  Temporal profile ranges from a peak of extremely high expression to a trough of extremely low expression.  Peak expression observed during early larval stages.  "
FBgn0264295	CG43773	1.136292614	0.005790646	0.999936032	NA	NA	NA	NA	NA	NA	This gene is referred to in FlyBase by the symbol Dmel\CG43773 (FBgn0264295). It is a protein_coding_gene from Drosophila melanogaster. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:4007690..4007984. It has the cytological map location 24D3. Its molecular function is described by: . It is involved in the biological process described with: . One allele is reported. No phenotypic data is available. No phenotypic class data is available.