ONTOLOGY ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count BP GO:0000280 nuclear division 43/130 416/18493 1.3636993062279e-38 2.49966082831574e-35 2.03837159457223e-35 KIF11/KIF20B/NUF2/RACGAP1/CCNA2/MASTL/CCNB1/RAD51/BUB1/NCAPH/CCNB2/CDCA5/ZWINT/BORA/MYBL2/SGO1/DLGAP5/PLK1/IGF1/PRC1/ANLN/AURKB/SGO2/AURKA/NEK2/KIF4A/CKS2/CDC6/DSCC1/KNSTRN/KIF14/UBE2C/KIF23/ASPM/TTK/MND1/NUSAP1/TRIP13/NDC80/TOP2A/CDCA8/PTTG1/NCAPG 43 BP GO:0048285 organelle fission 44/130 458/18493 3.95189357563023e-38 3.62191046206511e-35 2.95352046178681e-35 KIF11/KIF20B/NUF2/RACGAP1/CCNA2/MTFR2/MASTL/CCNB1/RAD51/BUB1/NCAPH/CCNB2/CDCA5/ZWINT/BORA/MYBL2/SGO1/DLGAP5/PLK1/IGF1/PRC1/ANLN/AURKB/SGO2/AURKA/NEK2/KIF4A/CKS2/CDC6/DSCC1/KNSTRN/KIF14/UBE2C/KIF23/ASPM/TTK/MND1/NUSAP1/TRIP13/NDC80/TOP2A/CDCA8/PTTG1/NCAPG 44 BP GO:0140014 mitotic nuclear division 36/130 277/18493 9.54330463778853e-36 5.83095913368879e-33 4.75490967917885e-33 KIF11/KIF20B/NUF2/RACGAP1/CCNA2/CCNB1/BUB1/NCAPH/CCNB2/CDCA5/ZWINT/BORA/MYBL2/SGO1/DLGAP5/PLK1/IGF1/PRC1/ANLN/AURKB/AURKA/NEK2/KIF4A/CDC6/DSCC1/KNSTRN/KIF14/UBE2C/KIF23/TTK/NUSAP1/TRIP13/NDC80/CDCA8/PTTG1/NCAPG 36 BP GO:0007059 chromosome segregation 37/130 312/18493 2.96414289758541e-35 1.35831848281851e-32 1.10765339857139e-32 NUF2/RACGAP1/CCNB1/SPC25/BUB1/HJURP/NCAPH/CDCA5/ZWINT/SGO1/DLGAP5/PLK1/CENPN/PRC1/SKA3/AURKB/SGO2/NEK2/KIF4A/NUP37/CDC6/DSCC1/KNSTRN/KIF14/KIF23/ECT2/TTK/NUSAP1/TRIP13/NDC80/TOP2A/CDCA8/BIRC5/BRCA1/PTTG1/ESCO2/NCAPG 37 BP GO:0000819 sister chromatid segregation 29/130 185/18493 3.4469750670852e-31 1.26366105959344e-28 1.0304641253181e-28 NUF2/RACGAP1/CCNB1/BUB1/NCAPH/CDCA5/ZWINT/SGO1/DLGAP5/PLK1/PRC1/AURKB/SGO2/NEK2/KIF4A/CDC6/DSCC1/KNSTRN/KIF14/KIF23/TTK/NUSAP1/TRIP13/NDC80/TOP2A/CDCA8/PTTG1/ESCO2/NCAPG 29 BP GO:0000070 mitotic sister chromatid segregation 26/130 153/18493 6.03120069284649e-29 1.8425318116646e-26 1.50250964628807e-26 NUF2/RACGAP1/CCNB1/BUB1/NCAPH/CDCA5/ZWINT/SGO1/DLGAP5/PLK1/PRC1/AURKB/NEK2/KIF4A/CDC6/DSCC1/KNSTRN/KIF14/KIF23/TTK/NUSAP1/TRIP13/NDC80/CDCA8/PTTG1/NCAPG 26 BP GO:0098813 nuclear chromosome segregation 30/130 258/18493 3.02406528455774e-28 7.91873095227762e-26 6.45740256251427e-26 NUF2/RACGAP1/CCNB1/BUB1/NCAPH/CDCA5/ZWINT/SGO1/DLGAP5/PLK1/PRC1/AURKB/SGO2/NEK2/KIF4A/CDC6/DSCC1/KNSTRN/KIF14/KIF23/ECT2/TTK/NUSAP1/TRIP13/NDC80/TOP2A/CDCA8/PTTG1/ESCO2/NCAPG 30 BP GO:0007088 regulation of mitotic nuclear division 22/130 177/18493 1.79690234623616e-21 4.1171525008136e-19 3.35737017323072e-19 KIF11/KIF20B/CCNA2/CCNB1/BUB1/CCNB2/CDCA5/BORA/DLGAP5/PLK1/IGF1/ANLN/AURKB/AURKA/NEK2/CDC6/UBE2C/TTK/NUSAP1/TRIP13/NDC80/PTTG1 22 BP GO:0007051 spindle organization 21/130 165/18493 9.46977917205795e-21 1.92867835804247e-18 1.57275864611957e-18 KIF11/NUF2/RACGAP1/CCNB1/SPC25/BORA/MYBL2/PLK1/PRC1/AURKB/AURKA/NEK2/KIF4A/INTS13/KNSTRN/HAUS8/KIF23/ASPM/TTK/AUNIP/NDC80 21 BP GO:0051783 regulation of nuclear division 22/130 201/18493 3.0470837335461e-20 5.58530448359e-18 4.55458831751101e-18 KIF11/KIF20B/CCNA2/CCNB1/BUB1/CCNB2/CDCA5/BORA/DLGAP5/PLK1/IGF1/ANLN/AURKB/AURKA/NEK2/CDC6/UBE2C/TTK/NUSAP1/TRIP13/NDC80/PTTG1 22 BP GO:1902850 microtubule cytoskeleton organization involved in mitosis 19/130 129/18493 4.28596075311656e-20 7.14196914587515e-18 5.82398494681868e-18 KIF11/NUF2/RACGAP1/CCNB1/SPC25/CENPA/BORA/MYBL2/PLK1/PRC1/AURKB/AURKA/NEK2/KIF4A/INTS13/KIF23/TTK/NUSAP1/NDC80 19 BP GO:0007052 mitotic spindle organization 17/130 108/18493 1.3708606493946e-18 2.09398964195025e-16 1.70756326503538e-16 KIF11/NUF2/RACGAP1/CCNB1/SPC25/BORA/MYBL2/PLK1/PRC1/AURKB/AURKA/NEK2/KIF4A/INTS13/KIF23/TTK/NDC80 17 BP GO:0051983 regulation of chromosome segregation 15/130 103/18493 5.35747532026042e-16 7.55404020156719e-14 6.16001210912534e-14 RACGAP1/CCNB1/BUB1/CDCA5/DLGAP5/PLK1/AURKB/NEK2/CDC6/KNSTRN/ECT2/TTK/TRIP13/NDC80/PTTG1 15 BP GO:0044839 cell cycle G2/M phase transition 19/130 218/18493 9.85481502107105e-16 1.29027685240166e-13 1.0521682202948e-13 CDK1/CCNA2/MASTL/CCNB1/CCNB2/BORA/PLK1/MELK/HMMR/AURKB/AURKA/GTSE1/NEK2/CDC6/KIF14/HAUS8/CDC25A/BRCA1/FOXM1 19 BP GO:1903046 meiotic cell cycle process 18/130 188/18493 1.12136793516328e-15 1.37031161676952e-13 1.11743331082937e-13 NUF2/MASTL/RAD51/BUB1/NCAPH/EXO1/SGO1/PLK1/SGO2/AURKA/CKS2/CDC25A/ASPM/TTK/MND1/TRIP13/TOP2A/PTTG1 18 BP GO:0000086 G2/M transition of mitotic cell cycle 18/130 199/18493 3.07171899726364e-15 3.51903807624016e-13 2.86963222112788e-13 CDK1/CCNA2/MASTL/CCNB1/CCNB2/BORA/PLK1/MELK/HMMR/AURKB/AURKA/NEK2/CDC6/KIF14/HAUS8/CDC25A/BRCA1/FOXM1 18 BP GO:0045787 positive regulation of cell cycle 23/130 390/18493 3.86618880105846e-15 4.16866121902362e-13 3.39937343498639e-13 KIF20B/CDK1/RACGAP1/CCNA2/CCNB1/CCNB2/CDCA5/DLGAP5/IGF1/AURKB/AURKA/GTSE1/CKS2/CDC6/CKS1B/KIF14/UBE2C/KIF23/CDC25A/ECT2/NUSAP1/NDC80/BRCA1 23 BP GO:0051321 meiotic cell cycle 19/130 249/18493 1.14260866246439e-14 1.1635564879429e-12 9.48832924385633e-13 NUF2/MASTL/RAD51/BUB1/NCAPH/EXO1/SGO1/PLK1/SGO2/AURKA/NEK2/CKS2/CDC25A/ASPM/TTK/MND1/TRIP13/TOP2A/PTTG1 19 BP GO:0000910 cytokinesis 16/130 163/18493 3.21618273454749e-14 3.10276997496081e-12 2.53018253908999e-12 CEP55/KIF20B/RACGAP1/CENPA/PLK1/PRC1/ANLN/AURKB/AURKA/KIF4A/KIF20A/CDC6/KIF14/KIF23/ECT2/NUSAP1 16 BP GO:0140013 meiotic nuclear division 16/130 171/18493 6.85338772209715e-14 6.28112984730204e-12 5.12200556072524e-12 NUF2/MASTL/RAD51/BUB1/NCAPH/SGO1/PLK1/SGO2/AURKA/CKS2/ASPM/TTK/MND1/TRIP13/TOP2A/PTTG1 16 BP GO:0090068 positive regulation of cell cycle process 19/130 286/18493 1.40838298350398e-13 1.22931714702991e-11 1.00245806344644e-11 KIF20B/CDK1/RACGAP1/CCNB1/CDCA5/DLGAP5/IGF1/AURKB/AURKA/GTSE1/CDC6/KIF14/UBE2C/KIF23/CDC25A/ECT2/NUSAP1/NDC80/BRCA1 19 BP GO:1901990 regulation of mitotic cell cycle phase transition 21/130 375/18493 1.87503476894605e-13 1.5622448779446e-11 1.27394706789636e-11 CDK1/CCNB1/BUB1/CDCA5/DLGAP5/PLK1/HMMR/ANLN/AURKB/AURKA/GTSE1/NEK2/CDC6/KIF14/UBE2C/HAUS8/CDC25A/TTK/TRIP13/NDC80/BRCA1 21 BP GO:0008608 attachment of spindle microtubules to kinetochore 9/130 32/18493 7.74802495308922e-13 6.17483901696198e-11 5.03532971779711e-11 NUF2/RACGAP1/CCNB1/SGO1/AURKB/NEK2/KNSTRN/ECT2/NDC80 9 BP GO:1901987 regulation of cell cycle phase transition 21/130 412/18493 1.1527422955569e-12 8.80406928231584e-11 7.17935991092457e-11 CDK1/CCNB1/BUB1/CDCA5/DLGAP5/PLK1/HMMR/ANLN/AURKB/AURKA/GTSE1/NEK2/CDC6/KIF14/UBE2C/HAUS8/CDC25A/TTK/TRIP13/NDC80/BRCA1 21 BP GO:0051304 chromosome separation 12/130 89/18493 1.30361003423205e-12 9.55806877098941e-11 7.79421578361901e-11 CCNB1/BUB1/NCAPH/DLGAP5/PLK1/AURKB/CDC6/TTK/TRIP13/NDC80/TOP2A/PTTG1 12 BP GO:0061640 cytoskeleton-dependent cytokinesis 12/130 98/18493 4.22967499940188e-12 2.98192087457832e-10 2.43163501989905e-10 CEP55/KIF20B/RACGAP1/CENPA/PLK1/ANLN/AURKB/KIF4A/KIF20A/KIF23/ECT2/NUSAP1 12 BP GO:0010965 regulation of mitotic sister chromatid separation 10/130 57/18493 6.77275121563806e-12 4.59794554750539e-10 3.7494373201583e-10 CCNB1/BUB1/DLGAP5/PLK1/AURKB/CDC6/TTK/TRIP13/NDC80/PTTG1 10 BP GO:0033045 regulation of sister chromatid segregation 11/130 80/18493 9.3652956232501e-12 6.13092388479194e-10 4.9995187161711e-10 CCNB1/BUB1/CDCA5/DLGAP5/PLK1/AURKB/CDC6/TTK/TRIP13/NDC80/PTTG1 11 BP GO:0007093 mitotic cell cycle checkpoint 14/130 166/18493 1.12678554738944e-11 7.09770543925149e-10 5.78788969692314e-10 CDK1/CCNB1/BUB1/ZWINT/PLK1/AURKB/AURKA/GTSE1/CDC6/TTK/TRIP13/NDC80/TOP2A/BRCA1 14 BP GO:0051306 mitotic sister chromatid separation 10/130 60/18493 1.16165391804443e-11 7.09770543925149e-10 5.78788969692314e-10 CCNB1/BUB1/DLGAP5/PLK1/AURKB/CDC6/TTK/TRIP13/NDC80/PTTG1 10 BP GO:0032465 regulation of cytokinesis 11/130 84/18493 1.62135250757726e-11 9.37768744157151e-10 7.64712215639105e-10 KIF20B/RACGAP1/PLK1/PRC1/AURKB/AURKA/KIF20A/CDC6/KIF14/KIF23/ECT2 11 BP GO:1905818 regulation of chromosome separation 10/130 62/18493 1.63713037714287e-11 9.37768744157151e-10 7.64712215639105e-10 CCNB1/BUB1/DLGAP5/PLK1/AURKB/CDC6/TTK/TRIP13/NDC80/PTTG1 10 BP GO:0000281 mitotic cytokinesis 11/130 85/18493 1.8513668408141e-11 1.02835012703401e-09 8.38577644005109e-10 CEP55/KIF20B/RACGAP1/CENPA/PLK1/ANLN/KIF4A/KIF20A/KIF23/ECT2/NUSAP1 11 BP GO:0000075 cell cycle checkpoint 15/130 216/18493 3.26604371845948e-11 1.76078180468712e-09 1.43584584526701e-09 CDK1/CCNB1/BUB1/ZWINT/PLK1/AURKB/AURKA/GTSE1/CDC6/TTK/TRIP13/NDC80/TOP2A/DNA2/BRCA1 15 BP GO:0033047 regulation of mitotic sister chromatid segregation 10/130 68/18493 4.27264946739918e-11 2.23764756392648e-09 1.82471044923514e-09 CCNB1/BUB1/DLGAP5/PLK1/AURKB/CDC6/TTK/TRIP13/NDC80/PTTG1 10 BP GO:0030071 regulation of mitotic metaphase/anaphase transition 9/130 51/18493 7.51173369044064e-11 3.82472440404936e-09 3.11890697088471e-09 CCNB1/BUB1/DLGAP5/PLK1/AURKB/CDC6/TTK/TRIP13/NDC80 9 BP GO:1902099 regulation of metaphase/anaphase transition of cell cycle 9/130 53/18493 1.081355280382e-10 5.3570925106492e-09 4.36849074862714e-09 CCNB1/BUB1/DLGAP5/PLK1/AURKB/CDC6/TTK/TRIP13/NDC80 9 BP GO:0051302 regulation of cell division 13/130 162/18493 1.18925951400369e-10 5.73661233991782e-09 4.67797371159348e-09 KIF20B/RACGAP1/ORC6/PLK1/PRC1/AURKB/AURKA/KIF20A/CDC6/KIF14/KIF23/ECT2/ASPM 13 BP GO:0007091 metaphase/anaphase transition of mitotic cell cycle 9/130 54/18493 1.28998533826318e-10 6.06293108983693e-09 4.94407336122459e-09 CCNB1/BUB1/DLGAP5/PLK1/AURKB/CDC6/TTK/TRIP13/NDC80 9 BP GO:0071103 DNA conformation change 16/130 283/18493 1.50773603503546e-10 6.90920038054999e-09 5.63417149934303e-09 CDK1/HELLS/CCNB1/RAD51/HJURP/NCAPH/CENPA/CDCA5/CENPN/ASF1B/SUPV3L1/NUSAP1/TOP2A/DNA2/NCAPG/GINS2 16 BP GO:0044784 metaphase/anaphase transition of cell cycle 9/130 56/18493 1.81614346384353e-10 8.11949016884193e-09 6.62111352672096e-09 CCNB1/BUB1/DLGAP5/PLK1/AURKB/CDC6/TTK/TRIP13/NDC80 9 BP GO:0051225 spindle assembly 11/130 105/18493 1.92045014577608e-10 8.37828762988057e-09 6.83215231540495e-09 KIF11/RACGAP1/MYBL2/PLK1/AURKB/AURKA/NEK2/KIF4A/HAUS8/KIF23/ASPM 11 BP GO:0032506 cytokinetic process 8/130 38/18493 1.96544663439642e-10 8.37828762988057e-09 6.83215231540495e-09 CEP55/KIF20B/RACGAP1/ANLN/AURKB/KIF20A/KIF23/ECT2 8 BP GO:1902749 regulation of cell cycle G2/M phase transition 13/130 170/18493 2.17389597067581e-10 9.05625298692898e-09 7.38500545062116e-09 CDK1/CCNB1/PLK1/HMMR/AURKB/AURKA/GTSE1/NEK2/CDC6/KIF14/HAUS8/CDC25A/BRCA1 13 BP GO:2000816 negative regulation of mitotic sister chromatid separation 8/130 39/18493 2.45816398864447e-10 1.00129213137451e-08 8.16512950614068e-09 CCNB1/BUB1/PLK1/AURKB/TTK/TRIP13/NDC80/PTTG1 8 BP GO:1905819 negative regulation of chromosome separation 8/130 40/18493 3.05469334370454e-10 1.21722889108922e-08 9.92600583080193e-09 CCNB1/BUB1/PLK1/AURKB/TTK/TRIP13/NDC80/PTTG1 8 BP GO:0010948 negative regulation of cell cycle process 16/130 304/18493 4.31884038990657e-10 1.68434775206356e-08 1.37351698850332e-08 CDK1/CCNB1/RAD51/BUB1/PLK1/AURKB/AURKA/GTSE1/NEK2/CDC6/TTK/RRM2/TRIP13/NDC80/BRCA1/PTTG1 16 BP GO:0033048 negative regulation of mitotic sister chromatid segregation 8/130 42/18493 4.63341957805554e-10 1.76938710136996e-08 1.44286311421905e-08 CCNB1/BUB1/PLK1/AURKB/TTK/TRIP13/NDC80/PTTG1 8 BP GO:0045132 meiotic chromosome segregation 10/130 89/18493 6.5990826553781e-10 2.46859561373634e-08 2.01303917736561e-08 NUF2/BUB1/NCAPH/SGO1/PLK1/SGO2/TTK/TRIP13/TOP2A/PTTG1 10 BP GO:0006260 DNA replication 15/130 268/18493 6.74534224754393e-10 2.47137422159785e-08 2.01530501890427e-08 CDK1/MCM10/ORC6/CCNA2/RAD51/EXO1/DBF4/CDC6/DSCC1/RFC5/RRM2/DNA2/BRCA1/ESCO2/GINS2 15 BP GO:0033046 negative regulation of sister chromatid segregation 8/130 44/18493 6.87616395534591e-10 2.47137422159785e-08 2.01530501890427e-08 CCNB1/BUB1/PLK1/AURKB/TTK/TRIP13/NDC80/PTTG1 8 BP GO:0010389 regulation of G2/M transition of mitotic cell cycle 12/130 153/18493 8.29678429396579e-10 2.87535002407081e-08 2.34473083192957e-08 CDK1/CCNB1/PLK1/HMMR/AURKB/AURKA/NEK2/CDC6/KIF14/HAUS8/CDC25A/BRCA1 12 BP GO:0051985 negative regulation of chromosome segregation 8/130 45/18493 8.31388713997562e-10 2.87535002407081e-08 2.34473083192957e-08 CCNB1/BUB1/PLK1/AURKB/TTK/TRIP13/NDC80/PTTG1 8 BP GO:0045931 positive regulation of mitotic cell cycle 12/130 157/18493 1.11723411591121e-09 3.79238913789861e-08 3.09253887835072e-08 KIF20B/CDK1/CCNB1/CDCA5/DLGAP5/IGF1/AURKA/CDC6/UBE2C/CDC25A/NUSAP1/NDC80 12 BP GO:0007143 female meiotic nuclear division 7/130 30/18493 1.2827169533607e-09 4.24085900072195e-08 3.45824778535342e-08 MASTL/NCAPH/PLK1/AURKA/TTK/TRIP13/TOP2A 7 BP GO:0045930 negative regulation of mitotic cell cycle 15/130 281/18493 1.29562522662536e-09 4.24085900072195e-08 3.45824778535342e-08 CDK1/CCNB1/BUB1/ZWINT/PLK1/AURKB/AURKA/GTSE1/CDC6/TTK/TRIP13/NDC80/TOP2A/BRCA1/PTTG1 15 BP GO:0045839 negative regulation of mitotic nuclear division 8/130 52/18493 2.78554384894454e-09 8.95772258792164e-08 7.30465792336332e-08 CCNB1/BUB1/PLK1/AURKB/TTK/TRIP13/NDC80/PTTG1 8 BP GO:0007094 mitotic spindle assembly checkpoint 7/130 34/18493 3.31142686981957e-09 9.95056631537586e-08 8.11428154468299e-08 CCNB1/BUB1/PLK1/AURKB/TTK/TRIP13/NDC80 7 BP GO:0031577 spindle checkpoint 7/130 34/18493 3.31142686981957e-09 9.95056631537586e-08 8.11428154468299e-08 CCNB1/BUB1/PLK1/AURKB/TTK/TRIP13/NDC80 7 BP GO:0071173 spindle assembly checkpoint 7/130 34/18493 3.31142686981957e-09 9.95056631537586e-08 8.11428154468299e-08 CCNB1/BUB1/PLK1/AURKB/TTK/TRIP13/NDC80 7 BP GO:0071174 mitotic spindle checkpoint 7/130 34/18493 3.31142686981957e-09 9.95056631537586e-08 8.11428154468299e-08 CCNB1/BUB1/PLK1/AURKB/TTK/TRIP13/NDC80 7 BP GO:0045841 negative regulation of mitotic metaphase/anaphase transition 7/130 36/18493 5.07883960344723e-09 1.50153435372883e-07 1.22444010813159e-07 CCNB1/BUB1/PLK1/AURKB/TTK/TRIP13/NDC80 7 BP GO:0031145 anaphase-promoting complex-dependent catabolic process 7/130 37/18493 6.2274830877459e-09 1.75615023074434e-07 1.43206898536019e-07 CDK1/CCNB1/PLK1/AURKB/AURKA/UBE2C/PTTG1 7 BP GO:0032467 positive regulation of cytokinesis 7/130 37/18493 6.2274830877459e-09 1.75615023074434e-07 1.43206898536019e-07 KIF20B/RACGAP1/AURKB/CDC6/KIF14/KIF23/ECT2 7 BP GO:1902100 negative regulation of metaphase/anaphase transition of cell cycle 7/130 37/18493 6.2274830877459e-09 1.75615023074434e-07 1.43206898536019e-07 CCNB1/BUB1/PLK1/AURKB/TTK/TRIP13/NDC80 7 BP GO:0051784 negative regulation of nuclear division 8/130 60/18493 9.03589278912286e-09 2.47205843021824e-07 2.01586296316645e-07 CCNB1/BUB1/PLK1/AURKB/TTK/TRIP13/NDC80/PTTG1 8 BP GO:0090307 mitotic spindle assembly 8/130 60/18493 9.03589278912286e-09 2.47205843021824e-07 2.01586296316645e-07 KIF11/RACGAP1/MYBL2/PLK1/AURKB/NEK2/KIF4A/KIF23 8 BP GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity 9/130 87/18493 1.02392541001374e-08 2.75819278284371e-07 2.24919387351082e-07 CCNA2/CCNB1/CCNB2/CDKN3/PLK1/CKS2/CDC6/CKS1B/CDC25A 9 BP GO:1901991 negative regulation of mitotic cell cycle phase transition 12/130 191/18493 1.03827224231432e-08 2.75819278284371e-07 2.24919387351082e-07 CDK1/CCNB1/BUB1/PLK1/AURKB/AURKA/GTSE1/CDC6/TTK/TRIP13/NDC80/BRCA1 12 BP GO:0000022 mitotic spindle elongation 5/130 12/18493 1.20967714703516e-08 3.07963640349369e-07 2.51131805378645e-07 RACGAP1/PRC1/AURKB/KIF4A/KIF23 5 BP GO:0007077 mitotic nuclear envelope disassembly 5/130 12/18493 1.20967714703516e-08 3.07963640349369e-07 2.51131805378645e-07 CDK1/CCNB1/CCNB2/PLK1/VRK1 5 BP GO:0051988 regulation of attachment of spindle microtubules to kinetochore 5/130 12/18493 1.20967714703516e-08 3.07963640349369e-07 2.51131805378645e-07 RACGAP1/CCNB1/NEK2/KNSTRN/ECT2 5 BP GO:1904029 regulation of cyclin-dependent protein kinase activity 9/130 91/18493 1.52811081113485e-08 3.83702344768517e-07 3.12893634003098e-07 CCNA2/CCNB1/CCNB2/CDKN3/PLK1/CKS2/CDC6/CKS1B/CDC25A 9 BP GO:0051231 spindle elongation 5/130 13/18493 1.95465891796828e-08 4.84174296842684e-07 3.94824418707676e-07 RACGAP1/PRC1/AURKB/KIF4A/KIF23 5 BP GO:0030261 chromosome condensation 7/130 45/18493 2.61982517578273e-08 6.40285272961299e-07 5.22126561348979e-07 CDK1/CCNB1/NCAPH/CDCA5/NUSAP1/TOP2A/NCAPG 7 BP GO:0006323 DNA packaging 12/130 209/18493 2.83659339018591e-08 6.84141537396154e-07 5.57889558734625e-07 CDK1/HELLS/CCNB1/HJURP/NCAPH/CENPA/CDCA5/CENPN/ASF1B/NUSAP1/TOP2A/NCAPG 12 BP GO:1901988 negative regulation of cell cycle phase transition 12/130 211/18493 3.15234883799983e-08 7.50422781825153e-07 6.11939213938449e-07 CDK1/CCNB1/BUB1/PLK1/AURKB/AURKA/GTSE1/CDC6/TTK/TRIP13/NDC80/BRCA1 12 BP GO:0007292 female gamete generation 10/130 134/18493 3.62573582495457e-08 8.52047918864324e-07 6.94810374012887e-07 MASTL/CCNB1/NCAPH/PLK1/IGF1/AURKA/ASPM/TTK/TRIP13/TOP2A 10 BP GO:0030397 membrane disassembly 5/130 16/18493 6.5226072807129e-08 1.49449239319334e-06 1.2186976761332e-06 CDK1/CCNB1/CCNB2/PLK1/VRK1 5 BP GO:0051081 nuclear envelope disassembly 5/130 16/18493 6.5226072807129e-08 1.49449239319334e-06 1.2186976761332e-06 CDK1/CCNB1/CCNB2/PLK1/VRK1 5 BP GO:2001251 negative regulation of chromosome organization 10/130 144/18493 7.19266857308772e-08 1.62767425857652e-06 1.32730206286999e-06 CCNB1/BUB1/PLK1/AURKB/TTK/TRIP13/NDC80/TOP2A/BRCA1/PTTG1 10 BP GO:0033044 regulation of chromosome organization 14/130 330/18493 8.55544715147742e-08 1.91245544251928e-06 1.55952951926803e-06 CCNB1/BUB1/CDCA5/DLGAP5/PLK1/AURKB/NEK2/CDC6/TTK/TRIP13/NDC80/TOP2A/BRCA1/PTTG1 14 BP GO:0044843 cell cycle G1/S phase transition 13/130 282/18493 9.75394991451526e-08 2.15409520401283e-06 1.75657690280427e-06 CDK1/MCM10/ORC6/CCNA2/CCNB1/CDKN3/DBF4/AURKA/GTSE1/CDC6/KIF14/CDC25A/RRM2 13 BP GO:0034502 protein localization to chromosome 8/130 81/18493 1.00408175363313e-07 2.19104982667801e-06 1.78671189242988e-06 CDK1/CENPA/CDCA5/PLK1/AURKB/TTK/NDC80/ESCO2 8 BP GO:0007062 sister chromatid cohesion 7/130 56/18493 1.25576243944849e-07 2.70801476648126e-06 2.20827574491251e-06 BUB1/CDCA5/SGO1/PLK1/SGO2/DSCC1/ESCO2 7 BP GO:0061982 meiosis I cell cycle process 9/130 118/18493 1.48644124333483e-07 3.16819395236366e-06 2.58353312795038e-06 RAD51/PLK1/AURKA/CKS2/CDC25A/MND1/TRIP13/TOP2A/PTTG1 9 BP GO:0016572 histone phosphorylation 6/130 37/18493 2.08919729943359e-07 4.38019321059668e-06 3.57186915843873e-06 CDK1/CCNA2/CCNB1/AURKB/AURKA/VRK1 6 BP GO:0051052 regulation of DNA metabolic process 15/130 412/18493 2.10287508201041e-07 4.38019321059668e-06 3.57186915843873e-06 CDK1/CCNA2/RAD51/AURKB/DBF4/NEK2/CDC6/DSCC1/RFC5/AUNIP/KPNA2/DNA2/BRCA1/FOXM1/ESCO2 15 BP GO:0000082 G1/S transition of mitotic cell cycle 12/130 263/18493 3.4726070725285e-07 7.15200984712892e-06 5.83217272973444e-06 CDK1/MCM10/ORC6/CCNB1/CDKN3/DBF4/AURKA/GTSE1/CDC6/KIF14/CDC25A/RRM2 12 BP GO:0071459 protein localization to chromosome, centromeric region 5/130 22/18493 3.80150527879515e-07 7.74239908447946e-06 6.31361110630306e-06 CDK1/CENPA/AURKB/TTK/NDC80 5 BP GO:0051256 mitotic spindle midzone assembly 4/130 10/18493 4.73847753099519e-07 9.54464759814745e-06 7.78327136380933e-06 RACGAP1/AURKB/KIF4A/KIF23 4 BP GO:0007080 mitotic metaphase plate congression 6/130 44/18493 6.09340609633683e-07 1.21404493202015e-05 9.90004194141682e-06 NUF2/CCNB1/CDCA5/KIF14/NDC80/CDCA8 6 BP GO:0035404 histone-serine phosphorylation 4/130 11/18493 7.40562808963203e-07 1.4596254073436e-05 1.19026506930136e-05 CCNB1/AURKB/AURKA/VRK1 4 BP GO:0006275 regulation of DNA replication 8/130 107/18493 8.73517162296391e-07 1.69303408647101e-05 1.38060034041912e-05 CDK1/CCNA2/DBF4/CDC6/DSCC1/RFC5/DNA2/ESCO2 8 BP GO:0051303 establishment of chromosome localization 7/130 74/18493 8.77459019174829e-07 1.69303408647101e-05 1.38060034041912e-05 NUF2/CCNB1/CDCA5/DLGAP5/KIF14/NDC80/CDCA8 7 BP GO:0050000 chromosome localization 7/130 75/18493 9.62169658546633e-07 1.83714269178748e-05 1.49811503852656e-05 NUF2/CCNB1/CDCA5/DLGAP5/KIF14/NDC80/CDCA8 7 BP GO:0007127 meiosis I 8/130 113/18493 1.32393432963684e-06 2.50182641878796e-05 2.04013754539806e-05 RAD51/PLK1/AURKA/CKS2/MND1/TRIP13/TOP2A/PTTG1 8 BP GO:0045840 positive regulation of mitotic nuclear division 6/130 51/18493 1.49327932734621e-06 2.79304184390367e-05 2.27761186340667e-05 CDCA5/DLGAP5/IGF1/AURKA/UBE2C/NUSAP1 6 BP GO:0051255 spindle midzone assembly 4/130 13/18493 1.58712882261182e-06 2.93859306247219e-05 2.39630295386368e-05 RACGAP1/AURKB/KIF4A/KIF23 4 BP GO:0031570 DNA integrity checkpoint 9/130 158/18493 1.76073218898237e-06 3.22742210240468e-05 2.63183127195259e-05 CDK1/CCNB1/PLK1/AURKA/GTSE1/CDC6/TOP2A/DNA2/BRCA1 9 BP GO:0007098 centrosome cycle 8/130 119/18493 1.95886091821346e-06 3.55504164661908e-05 2.8989916663503e-05 KIF11/CDK1/SGO1/PLK1/AURKA/NEK2/HAUS8/BRCA1 8 BP GO:0051781 positive regulation of cell division 7/130 84/18493 2.0836464480301e-06 3.74443523454822e-05 3.05343442332585e-05 KIF20B/RACGAP1/AURKB/CDC6/KIF14/KIF23/ECT2 7 BP GO:1901992 positive regulation of mitotic cell cycle phase transition 7/130 85/18493 2.25747097148959e-06 4.01742164149554e-05 3.27604371948412e-05 CDK1/CCNB1/CDCA5/DLGAP5/CDC6/UBE2C/CDC25A 7 BP GO:0051310 metaphase plate congression 6/130 57/18493 2.90694674522284e-06 5.12349363845525e-05 4.17800038281015e-05 NUF2/CCNB1/CDCA5/KIF14/NDC80/CDCA8 6 BP GO:0010639 negative regulation of organelle organization 13/130 384/18493 3.18047088692918e-06 5.55219346261065e-05 4.52758762851071e-05 CCNB1/BUB1/PLK1/IGF1/AURKB/NEK2/TTK/TRIP13/NDC80/TOP2A/BRCA1/PTTG1/ARHGAP6 13 BP GO:0051054 positive regulation of DNA metabolic process 10/130 220/18493 3.5556541088185e-06 6.14859809572105e-05 5.01393131531507e-05 CDK1/RAD51/AURKB/DBF4/NEK2/DSCC1/RFC5/DNA2/BRCA1/FOXM1 10 BP GO:1902750 negative regulation of cell cycle G2/M phase transition 6/130 60/18493 3.94197110773284e-06 6.74538626674207e-05 5.50058776166407e-05 CDK1/PLK1/AURKB/AURKA/CDC6/BRCA1 6 BP GO:0007076 mitotic chromosome condensation 4/130 16/18493 3.97436834046996e-06 6.74538626674207e-05 5.50058776166407e-05 NCAPH/CDCA5/NUSAP1/NCAPG 4 BP GO:0031023 microtubule organizing center organization 8/130 133/18493 4.50815261034713e-06 7.58114104106999e-05 6.18211173992557e-05 KIF11/CDK1/SGO1/PLK1/AURKA/NEK2/HAUS8/BRCA1 8 BP GO:0006310 DNA recombination 11/130 282/18493 4.98152420273621e-06 8.30103078510498e-05 6.76915250515351e-05 RAD51/EXO1/SUPV3L1/MND1/AUNIP/TRIP13/UCHL5/KPNA2/TOP2A/BRCA1/GINS2 11 BP GO:0034501 protein localization to kinetochore 4/130 17/18493 5.16897901659339e-06 8.53580048415827e-05 6.96059763258664e-05 CDK1/AURKB/TTK/NDC80 4 BP GO:0051785 positive regulation of nuclear division 6/130 64/18493 5.76937670893911e-06 9.44220313168338e-05 7.69973207396009e-05 CDCA5/DLGAP5/IGF1/AURKA/UBE2C/NUSAP1 6 BP GO:0006302 double-strand break repair 10/130 236/18493 6.62103234801239e-06 0.000107401347733688 8.75814246313702e-05 RAD51/CDCA5/EXO1/AUNIP/TRIP13/DNA2/BRCA1/FOXM1/ESCO2/GINS2 10 BP GO:1901989 positive regulation of cell cycle phase transition 7/130 100/18493 6.70980050161221e-06 0.000107886529118028 8.79770702889135e-05 CDK1/CCNB1/CDCA5/DLGAP5/CDC6/UBE2C/CDC25A 7 BP GO:2000241 regulation of reproductive process 8/130 142/18493 7.32150965386756e-06 0.000116698497352515 9.51628714736103e-05 IGF1/AURKA/INTS13/CDC25A/ASPM/TTK/TRIP13/AR 8 BP GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity 4/130 19/18493 8.32674163215467e-06 0.000131576874239134 0.000107295581829942 CCNB1/CKS2/CDC6/CKS1B 4 BP GO:0006261 DNA-dependent DNA replication 8/130 148/18493 9.92469687425812e-06 0.000155486917696711 0.000126793248416073 MCM10/ORC6/RAD51/CDC6/DSCC1/RFC5/DNA2/GINS2 8 BP GO:0072401 signal transduction involved in DNA integrity checkpoint 6/130 73/18493 1.24401658770727e-05 0.00019162037019054 0.00015625860721312 CDK1/CCNB1/PLK1/AURKA/GTSE1/BRCA1 6 BP GO:0072422 signal transduction involved in DNA damage checkpoint 6/130 73/18493 1.24401658770727e-05 0.00019162037019054 0.00015625860721312 CDK1/CCNB1/PLK1/AURKA/GTSE1/BRCA1 6 BP GO:0051383 kinetochore organization 4/130 21/18493 1.27180571833435e-05 0.000194268323475572 0.000158417905266209 NUF2/CENPA/CENPN/NDC80 4 BP GO:0072395 signal transduction involved in cell cycle checkpoint 6/130 74/18493 1.34604047174755e-05 0.000203908445017624 0.000166279031742628 CDK1/CCNB1/PLK1/AURKA/GTSE1/BRCA1 6 BP GO:1904031 positive regulation of cyclin-dependent protein kinase activity 4/130 23/18493 1.8612824260869e-05 0.000279650056312892 0.00022804323080616 CCNB1/CKS2/CDC6/CKS1B 4 BP GO:0010972 negative regulation of G2/M transition of mitotic cell cycle 5/130 48/18493 2.13522580582991e-05 0.000318200723746847 0.000259479729933972 CDK1/AURKB/AURKA/CDC6/BRCA1 5 BP GO:0006998 nuclear envelope organization 5/130 49/18493 2.36453680119108e-05 0.00034953193198252 0.00028502905413339 CDK1/CCNB1/CCNB2/PLK1/VRK1 5 BP GO:0042770 signal transduction in response to DNA damage 7/130 130/18493 3.7200432795187e-05 0.000545507146508623 0.000444838859529815 CDK1/CCNB1/PLK1/AURKA/GTSE1/BRCA1/FOXM1 7 BP GO:0007135 meiosis II 3/130 10/18493 3.92903389147409e-05 0.000567080245911182 0.000462430843422562 MASTL/BUB1/SGO2 3 BP GO:0061983 meiosis II cell cycle process 3/130 10/18493 3.92903389147409e-05 0.000567080245911182 0.000462430843422562 MASTL/BUB1/SGO2 3 BP GO:0071900 regulation of protein serine/threonine kinase activity 13/130 496/18493 4.77806774685529e-05 0.000684234232811386 0.000557965148070272 CDK1/CCNA2/CCNB1/CCNB2/CDKN3/PLK1/IGF1/DBF4/SMPD1/CKS2/CDC6/CKS1B/CDC25A 13 BP GO:0070601 centromeric sister chromatid cohesion 3/130 12/18493 7.12937413299735e-05 0.00100524175275263 0.000819733705980262 BUB1/SGO1/SGO2 3 BP GO:1904668 positive regulation of ubiquitin protein ligase activity 3/130 12/18493 7.12937413299735e-05 0.00100524175275263 0.000819733705980262 MASTL/PLK1/UBE2C 3 BP GO:0070192 chromosome organization involved in meiotic cell cycle 5/130 64/18493 8.69068706961296e-05 0.00121603277851913 0.000991625201996818 RAD51/BUB1/NCAPH/SGO2/TRIP13 5 BP GO:0007100 mitotic centrosome separation 3/130 13/18493 9.22057250821822e-05 0.00127961078561293 0.00104347047725636 KIF11/AURKA/NEK2 3 BP GO:0030330 DNA damage response, signal transduction by p53 class mediator 6/130 104/18493 9.28468273248881e-05 0.00127961078561293 0.00104347047725636 CDK1/CCNB1/AURKA/GTSE1/BRCA1/FOXM1 6 BP GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 11/130 389/18493 9.60934507665422e-05 0.00131447235264979 0.00107189866526701 CDK1/CCNB1/PBK/PLK1/AURKB/AURKA/KIF14/UBE2C/UCHL5/PTTG1/ERLIN1 11 BP GO:0032508 DNA duplex unwinding 5/130 66/18493 0.000100729890245263 0.00136768806533013 0.00111529391148752 RAD51/SUPV3L1/TOP2A/DNA2/GINS2 5 BP GO:0044774 mitotic DNA integrity checkpoint 6/130 107/18493 0.00010870205373122 0.00145438587218487 0.00118599244178512 CDK1/CCNB1/AURKA/GTSE1/CDC6/TOP2A 6 BP GO:0071156 regulation of cell cycle arrest 6/130 107/18493 0.00010870205373122 0.00145438587218487 0.00118599244178512 CDK1/CCNB1/AURKA/GTSE1/BRCA1/FOXM1 6 BP GO:0051299 centrosome separation 3/130 14/18493 0.000116750044697765 0.00155074515892031 0.00126456951541439 KIF11/AURKA/NEK2 3 BP GO:0007018 microtubule-based movement 9/130 269/18493 0.000121277399489009 0.0015992911745565 0.00130415681389166 KIF11/KIF20B/RACGAP1/DLGAP5/KIF4A/KIF20A/KIF14/KIF23/DLG2 9 BP GO:0072331 signal transduction by p53 class mediator 8/130 218/18493 0.000155451139026481 0.00203529955596814 0.00165970389035791 CDK1/CCNB1/AURKB/AURKA/GTSE1/BRCA1/FOXM1/TAF5 8 BP GO:0018105 peptidyl-serine phosphorylation 9/130 282/18493 0.000172904377531197 0.00224775690790556 0.00183295420749757 CDK1/MASTL/CCNB1/PLK1/AURKB/AURKA/VRK1/CHUK/TTK 9 BP GO:0022412 cellular process involved in reproduction in multicellular organism 10/130 350/18493 0.000185205720595862 0.00239071891445222 0.00194953390100908 MASTL/CCNB1/NCAPH/PLK1/IGF1/AURKA/ASPM/TTK/TRIP13/TOP2A 10 BP GO:0030866 cortical actin cytoskeleton organization 4/130 41/18493 0.000193014592945555 0.00247409614593848 0.00201752463734036 RACGAP1/ANLN/KIF23/ECT2 4 BP GO:0032392 DNA geometric change 5/130 76/18493 0.000196883878067205 0.00250616769789713 0.00204367768169175 RAD51/SUPV3L1/TOP2A/DNA2/GINS2 5 BP GO:0051653 spindle localization 4/130 42/18493 0.000212176996449479 0.00268220989304755 0.00218723292165706 CENPA/ASPM/NUSAP1/NDC80 4 BP GO:0051782 negative regulation of cell division 3/130 17/18493 0.000214763354953996 0.00269630979199092 0.002198730814958 ORC6/AURKB/ASPM 3 BP GO:1900182 positive regulation of protein localization to nucleus 5/130 78/18493 0.000222472258799125 0.0027740928597197 0.00226215973859476 CDK1/PLK1/IGF1/GTSE1/ECT2 5 BP GO:0070507 regulation of microtubule cytoskeleton organization 7/130 175/18493 0.000239645779739557 0.00296804536663924 0.00242032010832269 KIF11/BORA/PLK1/SKA3/AURKA/NEK2/BRCA1 7 BP GO:0007096 regulation of exit from mitosis 3/130 18/18493 0.000256394088923203 0.00315416352346464 0.0025720918846411 CDCA5/ANLN/UBE2C 3 BP GO:0048599 oocyte development 4/130 45/18493 0.000277877674558734 0.00339069532447914 0.00276497393445337 CCNB1/IGF1/AURKA/TRIP13 4 BP GO:0018209 peptidyl-serine modification 9/130 301/18493 0.000280389054177595 0.00339069532447914 0.00276497393445337 CDK1/MASTL/CCNB1/PLK1/AURKB/AURKA/VRK1/CHUK/TTK 9 BP GO:0071158 positive regulation of cell cycle arrest 5/130 82/18493 0.000281170588827512 0.00339069532447914 0.00276497393445337 CDK1/CCNB1/AURKA/GTSE1/BRCA1 5 BP GO:0030865 cortical cytoskeleton organization 4/130 46/18493 0.000302695887032353 0.00362641543091702 0.00295719408039863 RACGAP1/ANLN/KIF23/ECT2 4 BP GO:0007050 cell cycle arrest 8/130 241/18493 0.000307049329989109 0.00365468455759764 0.00298024640180817 KIF20B/CDK1/CCNB1/CDKN3/AURKA/GTSE1/BRCA1/FOXM1 8 BP GO:0048477 oogenesis 5/130 85/18493 0.000332387343578124 0.00393074839212065 0.00320536521481111 CCNB1/IGF1/AURKA/ASPM/TRIP13 5 BP GO:0010498 proteasomal protein catabolic process 11/130 452/18493 0.000352031067258353 0.00413636504028565 0.00337303721664549 CDK1/CCNB1/PBK/PLK1/AURKB/AURKA/KIF14/UBE2C/UCHL5/PTTG1/ERLIN1 11 BP GO:0031055 chromatin remodeling at centromere 4/130 48/18493 0.000357038076267582 0.00414209363163594 0.00337770864956673 HELLS/HJURP/CENPA/CENPN 4 BP GO:0051445 regulation of meiotic cell cycle 4/130 48/18493 0.000357038076267582 0.00414209363163594 0.00337770864956673 CDC25A/ASPM/TTK/TRIP13 4 BP GO:1904666 regulation of ubiquitin protein ligase activity 3/130 21/18493 0.000411503379562576 0.00474393518703272 0.00386848592505037 MASTL/PLK1/UBE2C 3 BP GO:0009994 oocyte differentiation 4/130 50/18493 0.000418024948551633 0.00478899831684464 0.00390523307199552 CCNB1/IGF1/AURKA/TRIP13 4 BP GO:0007064 mitotic sister chromatid cohesion 3/130 22/18493 0.000474036574090683 0.00539695056092063 0.00440099336520935 CDCA5/SGO1/DSCC1 3 BP GO:0007131 reciprocal meiotic recombination 4/130 53/18493 0.000522947205147074 0.00584489162825968 0.00476627106103238 RAD51/MND1/TRIP13/TOP2A 4 BP GO:0035825 homologous recombination 4/130 53/18493 0.000522947205147074 0.00584489162825968 0.00476627106103238 RAD51/MND1/TRIP13/TOP2A 4 BP GO:0044380 protein localization to cytoskeleton 4/130 53/18493 0.000522947205147074 0.00584489162825968 0.00476627106103238 KIF20B/ANLN/AURKA/TTK 4 BP GO:0016311 dephosphorylation 11/130 475/18493 0.000533600207503127 0.00592781321426201 0.00483389023702992 MASTL/CDKN3/DLGAP5/SMPD1/CDC25A/CILP2/CDCA2/DLG2/CA3/PTPRM/PLPPR4 11 BP GO:1902410 mitotic cytokinetic process 3/130 23/18493 0.000542350136565155 0.00598872168869837 0.0048835586171371 CEP55/KIF20B/KIF20A 3 BP GO:0006336 DNA replication-independent nucleosome assembly 4/130 54/18493 0.000561732680869845 0.0061656048145774 0.00502779960186057 HJURP/CENPA/CENPN/ASF1B 4 BP GO:0000077 DNA damage checkpoint 6/130 146/18493 0.00058362208071844 0.00636773377355298 0.00519262753521419 CDK1/CCNB1/PLK1/AURKA/GTSE1/BRCA1 6 BP GO:0034724 DNA replication-independent nucleosome organization 4/130 55/18493 0.000602519030469001 0.00646660792255301 0.00527325537659016 HJURP/CENPA/CENPN/ASF1B 4 BP GO:0048146 positive regulation of fibroblast proliferation 4/130 55/18493 0.000602519030469001 0.00646660792255301 0.00527325537659016 CCNA2/CCNB1/IGF1/CDC6 4 BP GO:0032886 regulation of microtubule-based process 7/130 204/18493 0.000603267842202163 0.00646660792255301 0.00527325537659016 KIF11/BORA/PLK1/SKA3/AURKA/NEK2/BRCA1 7 BP GO:0051642 centrosome localization 3/130 24/18493 0.000616655291794465 0.00657168110383288 0.00535893827630441 AURKA/INTS13/ASPM 3 BP GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 4/130 56/18493 0.000645363636364731 0.00675972311689459 0.00551227887902507 CDK1/CCNB1/AURKA/GTSE1 4 BP GO:0034508 centromere complex assembly 4/130 56/18493 0.000645363636364731 0.00675972311689459 0.00551227887902507 HELLS/HJURP/CENPA/CENPN 4 BP GO:0046605 regulation of centrosome cycle 4/130 56/18493 0.000645363636364731 0.00675972311689459 0.00551227887902507 KIF11/AURKA/NEK2/BRCA1 4 BP GO:0072431 signal transduction involved in mitotic G1 DNA damage checkpoint 4/130 57/18493 0.000690324031222053 0.00709939291103628 0.00578926576143309 CDK1/CCNB1/AURKA/GTSE1 4 BP GO:1902400 intracellular signal transduction involved in G1 DNA damage checkpoint 4/130 57/18493 0.000690324031222053 0.00709939291103628 0.00578926576143309 CDK1/CCNB1/AURKA/GTSE1 4 BP GO:0001556 oocyte maturation 3/130 25/18493 0.000697158060003562 0.00709939291103628 0.00578926576143309 CCNB1/AURKA/TRIP13 3 BP GO:0051307 meiotic chromosome separation 3/130 25/18493 0.000697158060003562 0.00709939291103628 0.00578926576143309 NCAPH/TTK/TOP2A 3 BP GO:0061842 microtubule organizing center localization 3/130 25/18493 0.000697158060003562 0.00709939291103628 0.00578926576143309 AURKA/INTS13/ASPM 3 BP GO:0000729 DNA double-strand break processing 3/130 26/18493 0.00078405933175229 0.00779592667306505 0.00635726067462162 EXO1/DNA2/BRCA1 3 BP GO:0071168 protein localization to chromatin 3/130 26/18493 0.00078405933175229 0.00779592667306505 0.00635726067462162 CDCA5/PLK1/ESCO2 3 BP GO:0072413 signal transduction involved in mitotic cell cycle checkpoint 4/130 59/18493 0.000786822932087852 0.00779592667306505 0.00635726067462162 CDK1/CCNB1/AURKA/GTSE1 4 BP GO:1902402 signal transduction involved in mitotic DNA damage checkpoint 4/130 59/18493 0.000786822932087852 0.00779592667306505 0.00635726067462162 CDK1/CCNB1/AURKA/GTSE1 4 BP GO:1902403 signal transduction involved in mitotic DNA integrity checkpoint 4/130 59/18493 0.000786822932087852 0.00779592667306505 0.00635726067462162 CDK1/CCNB1/AURKA/GTSE1 4 BP GO:0000723 telomere maintenance 6/130 157/18493 0.000853910836236209 0.00841515356355361 0.00686221498276976 RAD51/EXO1/AURKB/NEK2/RFC5/DNA2 6 BP GO:0040001 establishment of mitotic spindle localization 3/130 27/18493 0.000877554941986455 0.00860191555433782 0.00701451177945829 CENPA/NUSAP1/NDC80 3 BP GO:0010971 positive regulation of G2/M transition of mitotic cell cycle 3/130 28/18493 0.00097783574323042 0.00948345458910773 0.00773337095732218 CDK1/CCNB1/CDC25A 3 BP GO:0051984 positive regulation of chromosome segregation 3/130 28/18493 0.00097783574323042 0.00948345458910773 0.00773337095732218 CCNB1/DLGAP5/CDC6 3 BP GO:0031571 mitotic G1 DNA damage checkpoint 4/130 63/18493 0.00100775303261424 0.00967126339676392 0.00788652139053307 CDK1/CCNB1/AURKA/GTSE1 4 BP GO:0044819 mitotic G1/S transition checkpoint 4/130 63/18493 0.00100775303261424 0.00967126339676392 0.00788652139053307 CDK1/CCNB1/AURKA/GTSE1 4 BP GO:0031398 positive regulation of protein ubiquitination 5/130 109/18493 0.00103534741374947 0.00988433234063947 0.0080602704359882 MASTL/PLK1/UBE2C/BRCA1/AIMP2 5 BP GO:0044783 G1 DNA damage checkpoint 4/130 64/18493 0.00106914277674212 0.0101540865791104 0.00828024403039983 CDK1/CCNB1/AURKA/GTSE1 4 BP GO:2000045 regulation of G1/S transition of mitotic cell cycle 6/130 166/18493 0.00113954018436959 0.0107668925667498 0.00877996235379718 CDK1/CCNB1/AURKA/GTSE1/CDC6/KIF14 6 BP GO:0010458 exit from mitosis 3/130 30/18493 0.00119949184995449 0.0112197983800634 0.00914928859774888 CDCA5/ANLN/UBE2C 3 BP GO:2000573 positive regulation of DNA biosynthetic process 4/130 66/18493 0.00119971657528228 0.0112197983800634 0.00914928859774888 AURKB/NEK2/DSCC1/RFC5 4 BP GO:0046824 positive regulation of nucleocytoplasmic transport 4/130 67/18493 0.00126901638748974 0.0118076499404502 0.00962865760211291 CDK1/IGF1/GTSE1/ECT2 4 BP GO:0032200 telomere organization 6/130 170/18493 0.00128778315423993 0.0119217501097061 0.00972170164285331 RAD51/EXO1/AURKB/NEK2/RFC5/DNA2 6 BP GO:0044818 mitotic G2/M transition checkpoint 3/130 31/18493 0.00132122459526599 0.0121090234156128 0.00987441539619845 CDK1/CDC6/BRCA1 3 BP GO:1902751 positive regulation of cell cycle G2/M phase transition 3/130 31/18493 0.00132122459526599 0.0121090234156128 0.00987441539619845 CDK1/CCNB1/CDC25A 3 BP GO:0006270 DNA replication initiation 3/130 32/18493 0.00145045755176542 0.0131618252098317 0.0107329323788791 MCM10/ORC6/CDC6 3 BP GO:0031572 G2 DNA damage checkpoint 3/130 32/18493 0.00145045755176542 0.0131618252098317 0.0107329323788791 CDK1/PLK1/BRCA1 3 BP GO:0051443 positive regulation of ubiquitin-protein transferase activity 3/130 33/18493 0.00158735772832272 0.0143331365320963 0.0116880890548005 MASTL/PLK1/UBE2C 3 BP GO:1900180 regulation of protein localization to nucleus 5/130 121/18493 0.00164780476487715 0.0148060104608815 0.01207369848362 CDK1/PLK1/IGF1/GTSE1/ECT2 5 BP GO:0006997 nucleus organization 5/130 124/18493 0.00183538527914299 0.0164110303252151 0.013382526810696 CDK1/CCNB1/CCNB2/PLK1/VRK1 5 BP GO:0051056 regulation of small GTPase mediated signal transduction 8/130 321/18493 0.00196617231155939 0.0174341800749977 0.0142168637588634 RACGAP1/IGF1/DEPDC1B/KIF14/ECT2/FOXM1/ARHGAP6/ARHGAP11A 8 BP GO:0002478 antigen processing and presentation of exogenous peptide antigen 5/130 126/18493 0.00196883539308485 0.0174341800749977 0.0142168637588634 KIF11/RACGAP1/KIF4A/CHUK/KIF23 5 BP GO:1902806 regulation of cell cycle G1/S phase transition 6/130 185/18493 0.00197858220134853 0.0174362556493839 0.0142185563052374 CDK1/CCNB1/AURKA/GTSE1/CDC6/KIF14 6 BP GO:0071478 cellular response to radiation 6/130 186/18493 0.00203296570426113 0.0177710970918152 0.0144916058634838 RAD51/PBK/AURKB/CDC25A/ECT2/MFAP4 6 BP GO:1903322 positive regulation of protein modification by small protein conjugation or removal 5/130 127/18493 0.00203815842811142 0.0177710970918152 0.0144916058634838 MASTL/PLK1/UBE2C/BRCA1/AIMP2 5 BP GO:1903580 positive regulation of ATP metabolic process 3/130 36/18493 0.00204566365868686 0.0177710970918152 0.0144916058634838 CDK1/CCNB1/IGF1 3 BP GO:0060281 regulation of oocyte development 2/130 10/18493 0.00212673812728316 0.0183019295178875 0.0149244780861976 IGF1/AURKA 2 BP GO:1905879 regulation of oogenesis 2/130 10/18493 0.00212673812728316 0.0183019295178875 0.0149244780861976 IGF1/AURKA 2 BP GO:0031099 regeneration 6/130 188/18493 0.0021451188575879 0.018373845168031 0.0149831223697728 CDK1/CCNA2/CCNB1/IGF1/AURKA/NREP 6 BP GO:0045740 positive regulation of DNA replication 3/130 37/18493 0.00221481259466148 0.0187951457685856 0.0153266758499966 CDK1/DBF4/DNA2 3 BP GO:0051293 establishment of spindle localization 3/130 37/18493 0.00221481259466148 0.0187951457685856 0.0153266758499966 CENPA/NUSAP1/NDC80 3 BP GO:0034644 cellular response to UV 4/130 78/18493 0.00222558921280317 0.0187995623367199 0.0153302773814237 PBK/AURKB/CDC25A/MFAP4 4 BP GO:0051656 establishment of organelle localization 10/130 491/18493 0.00247397606934982 0.0208018263078818 0.016963042097908 NUF2/CCNB1/CENPA/CDCA5/DLGAP5/KIF14/KIF23/NUSAP1/NDC80/CDCA8 10 BP GO:0019884 antigen processing and presentation of exogenous antigen 5/130 134/18493 0.00257438986410858 0.021547290506443 0.0175709377891573 KIF11/RACGAP1/KIF4A/CHUK/KIF23 5 BP GO:0045835 negative regulation of meiotic nuclear division 2/130 11/18493 0.00258740293224511 0.0215577707945695 0.0175794840372635 TTK/TRIP13 2 BP GO:0070317 negative regulation of G0 to G1 transition 3/130 40/18493 0.00277342892735451 0.0230031458092345 0.0187581284917524 RAD51/RRM2/BRCA1 3 BP GO:0034504 protein localization to nucleus 7/130 269/18493 0.0029497574962671 0.0243554301380972 0.0198608612835433 CDK1/PLK1/IGF1/GTSE1/INTS13/ECT2/KPNA2 7 BP GO:0048002 antigen processing and presentation of peptide antigen 5/130 139/18493 0.00301548712779752 0.0247864928486675 0.020212375366875 KIF11/RACGAP1/KIF4A/CHUK/KIF23 5 BP GO:0033160 positive regulation of protein import into nucleus, translocation 2/130 12/18493 0.00309062477042814 0.0251782897964213 0.0205318698199203 CDK1/IGF1 2 BP GO:0055015 ventricular cardiac muscle cell development 2/130 12/18493 0.00309062477042814 0.0251782897964213 0.0205318698199203 CDK1/CCNB1 2 BP GO:0006890 retrograde vesicle-mediated transport, Golgi to ER 4/130 86/18493 0.00317362025453798 0.0257400262237527 0.0209899429969442 KIF11/RACGAP1/KIF4A/KIF23 4 BP GO:0042307 positive regulation of protein import into nucleus 3/130 42/18493 0.00318983576018764 0.0257575724600174 0.0210042512379617 CDK1/IGF1/ECT2 3 BP GO:0061351 neural precursor cell proliferation 5/130 143/18493 0.00340577553659093 0.0273806428007507 0.0223277989933477 SHCBP1/RACGAP1/MELK/KIF14/ASPM 5 BP GO:0000212 meiotic spindle organization 2/130 13/18493 0.00363579186958195 0.0284124984082741 0.023169235213914 AURKA/ASPM 2 BP GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway 2/130 13/18493 0.00363579186958195 0.0284124984082741 0.023169235213914 IGF1/AR 2 BP GO:0051315 attachment of mitotic spindle microtubules to kinetochore 2/130 13/18493 0.00363579186958195 0.0284124984082741 0.023169235213914 NUF2/NDC80 2 BP GO:0034080 CENP-A containing nucleosome assembly 3/130 44/18493 0.00364262800106078 0.0284124984082741 0.023169235213914 HJURP/CENPA/CENPN 3 BP GO:0061641 CENP-A containing chromatin organization 3/130 44/18493 0.00364262800106078 0.0284124984082741 0.023169235213914 HJURP/CENPA/CENPN 3 BP GO:0070316 regulation of G0 to G1 transition 3/130 44/18493 0.00364262800106078 0.0284124984082741 0.023169235213914 RAD51/RRM2/BRCA1 3 BP GO:1904591 positive regulation of protein import 3/130 44/18493 0.00364262800106078 0.0284124984082741 0.023169235213914 CDK1/IGF1/ECT2 3 BP GO:0048145 regulation of fibroblast proliferation 4/130 90/18493 0.0037374406667135 0.0290285116190078 0.0236715688971149 CCNA2/CCNB1/IGF1/CDC6 4 BP GO:0048144 fibroblast proliferation 4/130 91/18493 0.00388832553954325 0.0300729987931763 0.024523305645798 CCNA2/CCNB1/IGF1/CDC6 4 BP GO:0045023 G0 to G1 transition 3/130 46/18493 0.00413275368844995 0.0312075555421203 0.0254484904641863 RAD51/RRM2/BRCA1 3 BP GO:0045981 positive regulation of nucleotide metabolic process 3/130 46/18493 0.00413275368844995 0.0312075555421203 0.0254484904641863 CDK1/CCNB1/IGF1 3 BP GO:1900544 positive regulation of purine nucleotide metabolic process 3/130 46/18493 0.00413275368844995 0.0312075555421203 0.0254484904641863 CDK1/CCNB1/IGF1 3 BP GO:0010457 centriole-centriole cohesion 2/130 14/18493 0.00422229884039599 0.0312075555421203 0.0254484904641863 SGO1/NEK2 2 BP GO:0046606 negative regulation of centrosome cycle 2/130 14/18493 0.00422229884039599 0.0312075555421203 0.0254484904641863 NEK2/BRCA1 2 BP GO:0048308 organelle inheritance 2/130 14/18493 0.00422229884039599 0.0312075555421203 0.0254484904641863 CDK1/VRK1 2 BP GO:0048313 Golgi inheritance 2/130 14/18493 0.00422229884039599 0.0312075555421203 0.0254484904641863 CDK1/VRK1 2 BP GO:0072425 signal transduction involved in G2 DNA damage checkpoint 2/130 14/18493 0.00422229884039599 0.0312075555421203 0.0254484904641863 PLK1/BRCA1 2 BP GO:0090231 regulation of spindle checkpoint 2/130 14/18493 0.00422229884039599 0.0312075555421203 0.0254484904641863 CCNB1/NDC80 2 BP GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint 2/130 14/18493 0.00422229884039599 0.0312075555421203 0.0254484904641863 CCNB1/NDC80 2 BP GO:1903504 regulation of mitotic spindle checkpoint 2/130 14/18493 0.00422229884039599 0.0312075555421203 0.0254484904641863 CCNB1/NDC80 2 BP GO:0055023 positive regulation of cardiac muscle tissue growth 3/130 47/18493 0.00439209614961131 0.0323321776796688 0.0263655740116173 CDK1/CCNB1/IGF1 3 BP GO:0097711 ciliary basal body-plasma membrane docking 4/130 95/18493 0.00453312824413396 0.0332368962859902 0.0271033351859799 CDK1/PLK1/NEK2/HAUS8 4 BP GO:0072698 protein localization to microtubule cytoskeleton 3/130 48/18493 0.00466110002116756 0.0340390292382475 0.027757441937756 KIF20B/AURKA/TTK 3 BP GO:0001325 formation of extrachromosomal circular DNA 2/130 15/18493 0.0048495466181217 0.0348596821608513 0.0284266509710333 EXO1/DNA2 2 BP GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator 2/130 15/18493 0.0048495466181217 0.0348596821608513 0.0284266509710333 BRCA1/FOXM1 2 BP GO:0090656 t-circle formation 2/130 15/18493 0.0048495466181217 0.0348596821608513 0.0284266509710333 EXO1/DNA2 2 BP GO:0090737 telomere maintenance via telomere trimming 2/130 15/18493 0.0048495466181217 0.0348596821608513 0.0284266509710333 EXO1/DNA2 2 BP GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 4/130 98/18493 0.00506146271755348 0.0360998488765585 0.0294379564158343 KIF11/RACGAP1/KIF4A/KIF23 4 BP GO:0044773 mitotic DNA damage checkpoint 4/130 98/18493 0.00506146271755348 0.0360998488765585 0.0294379564158343 CDK1/CCNB1/AURKA/GTSE1 4 BP GO:0090316 positive regulation of intracellular protein transport 5/130 158/18493 0.00519592864146256 0.0369152604643445 0.0301028913540467 KIF20B/CDK1/IGF1/GTSE1/ECT2 5 BP GO:0046777 protein autophosphorylation 6/130 227/18493 0.00540550333921267 0.0380869786424143 0.031058379804306 MELK/AURKB/AURKA/NEK2/VRK1/TTK 6 BP GO:0000076 DNA replication checkpoint 2/130 16/18493 0.00551694240469031 0.0380869786424143 0.031058379804306 CDC6/DNA2 2 BP GO:0033158 regulation of protein import into nucleus, translocation 2/130 16/18493 0.00551694240469031 0.0380869786424143 0.031058379804306 CDK1/IGF1 2 BP GO:0042772 DNA damage response, signal transduction resulting in transcription 2/130 16/18493 0.00551694240469031 0.0380869786424143 0.031058379804306 BRCA1/FOXM1 2 BP GO:0051382 kinetochore assembly 2/130 16/18493 0.00551694240469031 0.0380869786424143 0.031058379804306 CENPA/CENPN 2 BP GO:0051447 negative regulation of meiotic cell cycle 2/130 16/18493 0.00551694240469031 0.0380869786424143 0.031058379804306 TTK/TRIP13 2 BP GO:0033260 nuclear DNA replication 3/130 51/18493 0.00552707927925924 0.0380869786424143 0.031058379804306 RAD51/RFC5/DNA2 3 BP GO:0060421 positive regulation of heart growth 3/130 51/18493 0.00552707927925924 0.0380869786424143 0.031058379804306 CDK1/CCNB1/IGF1 3 BP GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 4/130 101/18493 0.00562960920461385 0.0386482160002142 0.031516046010454 KIF11/RACGAP1/KIF4A/KIF23 4 BP GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 4/130 102/18493 0.00582806120555857 0.0398613290663763 0.0325052903059433 KIF11/RACGAP1/KIF4A/KIF23 4 BP GO:0016569 covalent chromatin modification 9/130 470/18493 0.00601089954089557 0.0409590292136119 0.0334004200668038 CDK1/HELLS/CCNA2/CCNB1/AURKB/AURKA/VRK1/BRCA1/TAF5 9 BP GO:0006266 DNA ligation 2/130 17/18493 0.00622389961132181 0.0414341005524857 0.0337878213940504 RAD51/TOP2A 2 BP GO:0006271 DNA strand elongation involved in DNA replication 2/130 17/18493 0.00622389961132181 0.0414341005524857 0.0337878213940504 DNA2/GINS2 2 BP GO:0055012 ventricular cardiac muscle cell differentiation 2/130 17/18493 0.00622389961132181 0.0414341005524857 0.0337878213940504 CDK1/CCNB1 2 BP GO:0061952 midbody abscission 2/130 17/18493 0.00622389961132181 0.0414341005524857 0.0337878213940504 CEP55/KIF20A 2 BP GO:1904355 positive regulation of telomere capping 2/130 17/18493 0.00622389961132181 0.0414341005524857 0.0337878213940504 AURKB/NEK2 2 BP GO:2001252 positive regulation of chromosome organization 5/130 165/18493 0.00622540397661302 0.0414341005524857 0.0337878213940504 CCNB1/DLGAP5/AURKB/NEK2/BRCA1 5 BP GO:2000278 regulation of DNA biosynthetic process 4/130 104/18493 0.00623884983769015 0.0414341005524857 0.0337878213940504 AURKB/NEK2/DSCC1/RFC5 4 BP GO:0031497 chromatin assembly 5/130 166/18493 0.00638335005711748 0.0422407243851853 0.0344455902759142 HELLS/HJURP/CENPA/CENPN/ASF1B 5 BP GO:0051438 regulation of ubiquitin-protein transferase activity 3/130 54/18493 0.00648346102936447 0.0427488635497304 0.0348599570681467 MASTL/PLK1/UBE2C 3 BP GO:2000242 negative regulation of reproductive process 3/130 55/18493 0.00682274614468537 0.0448247085419652 0.0365527241103687 IGF1/TTK/TRIP13 3 BP GO:0045143 homologous chromosome segregation 3/130 56/18493 0.00717240930553369 0.0469536652037259 0.0382888015558565 PLK1/TRIP13/PTTG1 3 BP GO:0006470 protein dephosphorylation 7/130 318/18493 0.00727459080758989 0.0472848402493343 0.0385588613168259 MASTL/CDKN3/DLGAP5/SMPD1/CDC25A/CDCA2/PTPRM 7 BP GO:1903829 positive regulation of cellular protein localization 7/130 318/18493 0.00727459080758989 0.0472848402493343 0.0385588613168259 KIF20B/CDK1/PLK1/IGF1/GTSE1/ECT2/NDC80 7 BP GO:0018107 peptidyl-threonine phosphorylation 4/130 109/18493 0.00734892791256609 0.0475639348309705 0.0387864515806576 CDK1/PLK1/VRK1/TTK 4 BP GO:0071214 cellular response to abiotic stimulus 7/130 319/18493 0.00739537448272045 0.0475639348309705 0.0387864515806576 GOT1/RAD51/PBK/AURKB/CDC25A/ECT2/MFAP4 7 BP GO:0104004 cellular response to environmental stimulus 7/130 319/18493 0.00739537448272045 0.0475639348309705 0.0387864515806576 GOT1/RAD51/PBK/AURKB/CDC25A/ECT2/MFAP4 7 BP GO:0045717 negative regulation of fatty acid biosynthetic process 2/130 19/18493 0.00775418263516062 0.0496972614344385 0.0405260925356205 BRCA1/ERLIN1 2 CC GO:0000775 chromosome, centromeric region 27/136 194/19659 1.0096940827376e-27 2.3121994494691e-25 1.79619263139636e-25 NUF2/HELLS/ERCC6L/CCNB1/SPC25/BUB1/HJURP/CENPA/CDCA5/ZWINT/SGO1/PLK1/CENPN/SKA3/AURKB/SGO2/AURKA/NEK2/NUP37/DSCC1/KNSTRN/TTK/NDC80/CDCA8/BIRC5/ESCO2/NCAPG 27 CC GO:0005819 spindle 30/136 333/19659 4.75955062772154e-25 5.44968546874116e-23 4.233495032026e-23 KIF11/KIF20B/CDK1/SHCBP1/RACGAP1/CKAP2L/CCNB1/SGO1/DLGAP5/PLK1/PRC1/SKA3/AURKB/AURKA/NEK2/KIF4A/KIF20A/VRK1/CDC6/KNSTRN/KIF14/HAUS8/KIF23/ECT2/ASPM/TTK/NUSAP1/AUNIP/CDCA8/BIRC5 30 CC GO:0000793 condensed chromosome 26/136 221/19659 9.13804543151439e-25 6.97537467938932e-23 5.41870062430151e-23 NUF2/ERCC6L/CCNB1/RAD51/SPC25/BUB1/HJURP/NCAPH/CENPA/CDCA5/ZWINT/SGO1/PLK1/CENPN/SKA3/AURKB/SGO2/AURKA/NEK2/NUP37/KNSTRN/NDC80/TOP2A/BIRC5/BRCA1/NCAPG 26 CC GO:0098687 chromosomal region 30/136 346/19659 1.47629361994837e-24 8.45178097420444e-23 6.56562162555987e-23 CDK1/NUF2/HELLS/ERCC6L/CCNB1/RAD51/SPC25/BUB1/HJURP/CENPA/CDCA5/ZWINT/SGO1/PLK1/CENPN/SKA3/AURKB/SGO2/AURKA/NEK2/NUP37/DSCC1/KNSTRN/TTK/NDC80/CDCA8/BIRC5/DNA2/ESCO2/NCAPG 30 CC GO:0000779 condensed chromosome, centromeric region 21/136 117/19659 3.95394627776874e-24 1.81090739521808e-22 1.40677246514298e-22 NUF2/ERCC6L/CCNB1/SPC25/BUB1/HJURP/CENPA/ZWINT/SGO1/PLK1/CENPN/SKA3/AURKB/SGO2/AURKA/NEK2/NUP37/KNSTRN/NDC80/BIRC5/NCAPG 21 CC GO:0000776 kinetochore 20/136 133/19659 2.11870651166641e-21 8.08639651952681e-20 6.28177895564253e-20 NUF2/ERCC6L/CCNB1/SPC25/BUB1/HJURP/CENPA/ZWINT/SGO1/PLK1/CENPN/SKA3/AURKB/SGO2/NEK2/NUP37/KNSTRN/TTK/NDC80/BIRC5 20 CC GO:0000777 condensed chromosome kinetochore 18/136 104/19659 1.6620790512023e-20 5.4373728960761e-19 4.22393022034871e-19 NUF2/ERCC6L/CCNB1/SPC25/BUB1/HJURP/CENPA/ZWINT/SGO1/PLK1/CENPN/SKA3/SGO2/NEK2/NUP37/KNSTRN/NDC80/BIRC5 18 CC GO:0030496 midbody 19/136 172/19659 9.0035088238463e-18 2.577254400826e-16 2.00209604109214e-16 CEP55/KIF20B/CDK1/SHCBP1/RACGAP1/PLK1/PRC1/ANLN/AURKB/AURKA/NEK2/KIF4A/KIF20A/KIF14/KIF23/ECT2/ASPM/CDCA8/BIRC5 19 CC GO:0000922 spindle pole 16/136 154/19659 1.06351279171015e-14 2.7060492144625e-13 2.10214809121656e-13 KIF11/KIF20B/CKAP2L/CCNB1/SGO1/DLGAP5/PLK1/PRC1/AURKB/AURKA/NEK2/CDC6/KNSTRN/HAUS8/ASPM/AUNIP 16 CC GO:0000780 condensed nuclear chromosome, centromeric region 8/136 24/19659 2.85469098801108e-12 6.53724236254538e-11 5.07834502077761e-11 NUF2/CCNB1/BUB1/CENPA/PLK1/AURKB/AURKA/NDC80 8 CC GO:0005876 spindle microtubule 10/136 54/19659 3.31772674677169e-12 6.9069038637338e-11 5.36551024119059e-11 KIF11/CDK1/PLK1/PRC1/SKA3/AURKB/AURKA/KIF4A/NUSAP1/BIRC5 10 CC GO:0000794 condensed nuclear chromosome 12/136 100/19659 4.59377169248099e-12 8.76644764648456e-11 6.81006505288849e-11 NUF2/CCNB1/RAD51/BUB1/NCAPH/CENPA/PLK1/AURKB/AURKA/NEK2/NDC80/BRCA1 12 CC GO:0072686 mitotic spindle 12/136 101/19659 5.18275583651048e-12 9.12962374277615e-11 7.09219219733013e-11 KIF11/KIF20B/CDK1/RACGAP1/CKAP2L/AURKB/AURKA/KNSTRN/KIF23/ECT2/ASPM/NUSAP1 12 CC GO:0005874 microtubule 20/136 414/19659 8.81381637156024e-12 1.44168853506235e-10 1.11995110285239e-10 KIF11/KIF20B/CDK1/RACGAP1/PLK1/PRC1/SKA3/AURKB/AURKA/GTSE1/NEK2/KIF4A/KIF20A/KNSTRN/KIF14/HAUS8/KIF23/ASPM/NUSAP1/BIRC5 20 CC GO:0051233 spindle midzone 8/136 34/19659 6.64989286040327e-11 1.01521697668823e-09 7.88653960286423e-10 KIF20B/RACGAP1/PLK1/AURKB/AURKA/CDC6/KIF14/CDCA8 8 CC GO:0000778 condensed nuclear chromosome kinetochore 6/136 14/19659 2.81476898173967e-10 4.0286381051149e-09 3.12957867048687e-09 NUF2/CCNB1/BUB1/CENPA/PLK1/NDC80 6 CC GO:0005875 microtubule associated complex 11/136 147/19659 6.13628969470748e-09 8.26594317698831e-08 6.42125670839358e-08 KIF11/KIF20B/AURKB/AURKA/KIF4A/KIF20A/KIF14/HAUS8/KIF23/CDCA8/BIRC5 11 CC GO:0000940 condensed chromosome outer kinetochore 5/136 12/19659 1.12102451985506e-08 1.4261923058156e-07 1.10791312196202e-07 CCNB1/BUB1/PLK1/SKA3/NDC80 5 CC GO:0000307 cyclin-dependent protein kinase holoenzyme complex 6/136 41/19659 3.61563841632636e-07 4.35779577546703e-06 3.38527918204518e-06 CDK1/CCNA2/CCNB1/CCNB2/CKS2/CKS1B 6 CC GO:0005871 kinesin complex 6/136 54/19659 1.92929339133656e-06 2.20904093308036e-05 1.71605570071515e-05 KIF11/KIF20B/KIF4A/KIF20A/KIF14/KIF23 6 CC GO:1902554 serine/threonine protein kinase complex 7/136 87/19659 2.3937247318506e-06 2.61029982663708e-05 2.02776681545239e-05 CDK1/CCNA2/CCNB1/CCNB2/CKS2/CKS1B/CHUK 7 CC GO:0032155 cell division site part 6/136 63/19659 4.82334907809879e-06 5.02066790402102e-05 3.90022006793635e-05 CEP55/RACGAP1/MASTL/ANLN/KIF20A/ECT2 6 CC GO:0032153 cell division site 6/136 68/19659 7.55314080997887e-06 7.52030106732679e-05 5.84201737705459e-05 CEP55/RACGAP1/MASTL/ANLN/KIF20A/ECT2 6 CC GO:1902911 protein kinase complex 7/136 107/19659 9.52469155681495e-06 9.08814319379427e-05 7.05996874167424e-05 CDK1/CCNA2/CCNB1/CCNB2/CKS2/CKS1B/CHUK 7 CC GO:0032154 cleavage furrow 5/136 54/19659 3.54535103018275e-05 0.00032475415436474 0.000252279715410899 CEP55/RACGAP1/MASTL/KIF20A/ECT2 5 CC GO:0070938 contractile ring 3/136 10/19659 3.75048776099065e-05 0.000330331422025715 0.000256612320488834 KIF20B/PRC1/ANLN 3 CC GO:0090543 Flemming body 4/136 28/19659 3.94374560274349e-05 0.000334488052973429 0.000259841328211949 CEP55/RACGAP1/KIF14/KIF23 4 CC GO:0045171 intercellular bridge 5/136 57/19659 4.61666622914434e-05 0.000377577345169305 0.000293314508543381 CEP55/KIF4A/KIF20A/KIF23/CDCA8 5 CC GO:0061695 transferase complex, transferring phosphorus-containing groups 9/136 259/19659 8.13055300650657e-05 0.000642033323617243 0.000498752616370094 CDK1/CCNA2/CCNB1/CCNB2/CKS2/CKS1B/CHUK/DNA2/TAF5 9 CC GO:0010369 chromocenter 3/136 14/19659 0.000111478808564606 0.000823504747138539 0.000639725590744257 AURKB/CDCA8/ESCO2 3 CC GO:0031616 spindle pole centrosome 3/136 14/19659 0.000111478808564606 0.000823504747138539 0.000639725590744257 DLGAP5/AURKB/AURKA 3 CC GO:0005721 pericentric heterochromatin 3/136 21/19659 0.000393134614060146 0.00281336958186792 0.00218551808474226 HELLS/CENPA/ESCO2 3 CC GO:0097431 mitotic spindle pole 3/136 27/19659 0.000838766201017299 0.00582052909190793 0.00452157856369772 KIF20B/AURKA/ASPM 3 CC GO:0072687 meiotic spindle 2/136 10/19659 0.00206152452086715 0.0138849739787817 0.0107863047686238 AURKA/ASPM 2 CC GO:0000795 synaptonemal complex 3/136 39/19659 0.00246682805995166 0.0156917673813592 0.0121898813488839 RAD51/PLK1/BRCA1 3 CC GO:0099086 synaptonemal structure 3/136 39/19659 0.00246682805995166 0.0156917673813592 0.0121898813488839 RAD51/PLK1/BRCA1 3 CC GO:0008278 cohesin complex 2/136 12/19659 0.00299627426806786 0.0185445083077713 0.0144059843898568 CDCA5/SGO2 2 CC GO:0000800 lateral element 2/136 13/19659 0.00352504487878048 0.02069834044207 0.0160791520786478 RAD51/BRCA1 2 CC GO:1990023 mitotic spindle midzone 2/136 13/19659 0.00352504487878048 0.02069834044207 0.0160791520786478 KIF20B/AURKB 2 CC GO:0000790 nuclear chromatin 8/136 369/19659 0.00419471513570424 0.0240147441519068 0.0186554436298425 RAD51/CENPA/CDCA5/ASF1B/UCHL5/TAF5/ESCO2/AR 8 CC GO:0045120 pronucleus 2/136 17/19659 0.00603600130972684 0.0337132756079865 0.0261895820627429 CCNA2/AURKA 2 CC GO:0044450 microtubule organizing center part 5/136 179/19659 0.00817012939610165 0.0445466578977923 0.0346053099734631 CEP55/PLK1/AURKA/TOP2A/BRCA1 5 CC GO:0043073 germ cell nucleus 2/136 21/19659 0.00915350132950292 0.0487477163827016 0.0378688304696694 AURKA/TRIP13 2 MF GO:0035173 histone kinase activity 5/126 17/17632 9.93979784995576e-08 1.74269072779157e-05 1.50597957630345e-05 CDK1/CCNB1/AURKB/AURKA/VRK1 5 MF GO:0008017 microtubule binding 12/126 240/17632 1.52200063562583e-07 1.74269072779157e-05 1.50597957630345e-05 KIF11/KIF20B/RACGAP1/PLK1/PRC1/KIF4A/KIF20A/KIF14/HAUS8/KIF23/NUSAP1/BIRC5 12 MF GO:0015631 tubulin binding 13/126 325/17632 5.88033378362617e-07 4.48865478816797e-05 3.87895702218147e-05 KIF11/KIF20B/RACGAP1/PLK1/PRC1/KIF4A/KIF20A/KIF14/HAUS8/KIF23/NUSAP1/BIRC5/BRCA1 13 MF GO:0043142 single-stranded DNA-dependent ATPase activity 4/126 14/17632 2.35445805398161e-06 0.000134792723590447 0.000116483714249616 RAD51/DSCC1/RFC5/DNA2 4 MF GO:0004674 protein serine/threonine kinase activity 14/126 455/17632 4.70041527531372e-06 0.000215279019609368 0.000186037488791364 CDK1/MASTL/CCNB1/BUB1/CCNB2/PBK/PLK1/MELK/AURKB/AURKA/NEK2/VRK1/CHUK/TTK 14 MF GO:0016887 ATPase activity 13/126 445/17632 1.81596248711469e-05 0.000693092349248774 0.000598949030837828 KIF11/KIF20B/ERCC6L/RAD51/SUPV3L1/KIF4A/KIF20A/DSCC1/KIF14/KIF23/RFC5/TOP2A/DNA2 13 MF GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 5/126 48/17632 2.30367791821234e-05 0.000753631776100894 0.000651265336276571 CCNA2/CCNB1/CCNB2/CKS2/CKS1B 5 MF GO:0003777 microtubule motor activity 6/126 84/17632 3.04567902463336e-05 0.000871825620801298 0.000753404811356673 KIF11/KIF20B/KIF4A/KIF20A/KIF14/KIF23 6 MF GO:0008094 DNA-dependent ATPase activity 6/126 87/17632 3.71827232350671e-05 0.000946093735647819 0.000817585025519605 ERCC6L/RAD51/DSCC1/RFC5/TOP2A/DNA2 6 MF GO:0097472 cyclin-dependent protein kinase activity 4/126 37/17632 0.000136791433143018 0.00313252381897512 0.0027070304664092 CDK1/CCNA2/CCNB1/CCNB2 4 MF GO:0003688 DNA replication origin binding 3/126 17/17632 0.000225187497780871 0.00468799427198359 0.00405122005577069 MCM10/ORC6/CDC6 3 MF GO:0042623 ATPase activity, coupled 10/126 357/17632 0.000245773142824968 0.00469017080890981 0.00405310095185036 KIF11/KIF20B/ERCC6L/RAD51/SUPV3L1/DSCC1/KIF14/RFC5/TOP2A/DNA2 10 MF GO:0140097 catalytic activity, acting on DNA 7/126 185/17632 0.000369193274176973 0.00650348152204053 0.00562010814131749 ERCC6L/RAD51/EXO1/SUPV3L1/TOP2A/DNA2/GINS2 7 MF GO:0003774 motor activity 6/126 137/17632 0.000452758300877568 0.00740583220721164 0.00639989177180321 KIF11/KIF20B/KIF4A/KIF20A/KIF14/KIF23 6 MF GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed 3/126 26/17632 0.000821516309957194 0.0125418156653465 0.0108382502646984 KIF11/KIF20B/KIF14 3 MF GO:0019887 protein kinase regulator activity 6/126 180/17632 0.00186614074896703 0.0267091394695906 0.0230812145266975 CCNA2/CCNB1/CCNB2/DBF4/CKS2/CKS1B 6 MF GO:0004693 cyclin-dependent protein serine/threonine kinase activity 3/126 36/17632 0.00214166397903554 0.0288494735999493 0.0249308252667914 CDK1/CCNB1/CCNB2 3 MF GO:0030295 protein kinase activator activity 4/126 80/17632 0.00258653031947492 0.0329064135088754 0.0284367076059231 CCNB1/DBF4/CKS2/CKS1B 4 MF GO:0019209 kinase activator activity 4/126 87/17632 0.00350362136281737 0.0398189018040183 0.0344102667853617 CCNB1/DBF4/CKS2/CKS1B 4 MF GO:0004712 protein serine/threonine/tyrosine kinase activity 3/126 43/17632 0.00356972063577904 0.0398189018040183 0.0344102667853617 AURKB/AURKA/TTK 3 MF GO:1990939 ATP-dependent microtubule motor activity 3/126 44/17632 0.00381112554983065 0.0398189018040183 0.0344102667853617 KIF11/KIF20B/KIF14 3 MF GO:0019207 kinase regulator activity 6/126 208/17632 0.00382539667986202 0.0398189018040183 0.0344102667853617 CCNA2/CCNB1/CCNB2/DBF4/CKS2/CKS1B 6 MF GO:0004386 helicase activity 5/126 151/17632 0.00459162183096568 0.0457165825778757 0.0395068606051052 HELLS/ERCC6L/SUPV3L1/DNA2/GINS2 5