>CHICK00947_HOG_0033281_Gallusgallus
-------MGVPL--------------------FGDSKPFYFRIWNGLSQKL-------QG
KKS-WDKH-----------------------------------------------LD---
-----------EIYLLQ----------------------------------QKR------
ICES-----------------------------------------P----------L---
-----LQAAKENNIPAITKLLAD---------------------------------GTCD
IYQR------------------GA--VGETALHVAALY---DNVEAALALMEAAPE----
---------------------------------------LVNERMTSELY----------
---------------------------EG--------------------------QTALH
IAAVNQNITLVKALLKRGANTCTAQATGHFFRRSSQN-LLYF-GEHVLSFAACVGNEEIV
QLLIE---NGADIRAQDYLGNT-----VLHILVLQPNKT---------------------
--------FACH---------MYSLILSYDQS-KEGPRSLEL------------------
------IPNNEGLTPFKLAGVEGNTV-----------MFQYLMQR--------------R
K-HNLW------SFGPLTTVL-----YDLTEIDSWAE-----------------------
----------DQSFLELIVS-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDLTPVKELVSLKWNMYGRPYFCFLALFYVLY------MVCFTMCCVYRP
----LKPR-TG---NKT------SSR-DNTVYVQKMLQESYITYE-DELRLVGELITVIG
AVVILILEIPDILRVGAA--KYFGQTILGGPFHII------------VITYACMILVTMV
MRLTSTTGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTEN------------
----PEN------------------LGQFYN------YPMSLFTTFELFLTIIDGP----
---ANYDVDLPFMYSVVYFAFAIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQIVAT
TVMLERKL--------PR-----------CLWPR-TGICGREYGLG--------------
----------------DRWYL-----RIEDRIDPNKHKMMRYTEAFKAHD----------
------------------RD--N--------------CDKSLEKLE--------------
------------------------------------VDRNILYKKDL--SI--P------
------SLSRG---------MSRTNSQ-SGWE-----------------ILRRNTF-HQL
HGEINHAM----------E--EEV-----YDV-------------------
>MELGA00972_HOG_0033281_Meleagrisgallopavo
------------------------------------------------------------
-KT---------------------------------------------------------
--------------LLL----------------------------------HCR------
ICES-----------------------------------------P----------L---
-----LQAAKENNIPVIMKLLTD---------------------------------GTCD
IYQR------------------GA--VGETALHVAALY---DNVEAALALMEAAPE----
---------------------------------------LVNERMTSELY----------
---------------------------EG--------------------------QTALH
IAAVNQNITLVKALLKRGANICTAQATGHFFRRSSQN-LLYF-GEHVLSFAACVGNEEIV
QLLIE---NGADIRAQDYLGNT-----ILHILVLQPNKT---------------------
--------FACH---------MYSLILSYDQS-KEGPRSLEL------------------
------IPNNEGLTPFKLAGVEGNTV-----------MFQYLMQR--------------R
K-HNLW------SFGPLTTVL-----YDLTEIDSWAE-----------------------
----------DQSFLELIVS-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDLTPVKELVNLKWNMYGRPYFCFLALFYVLY------MVCFTMCCVYRP
----LKPR-TG---NKT------SSR-DNTVYVQKMLQESYVTYE-DELRLVGELITVIG
AVVILILEIPDILRVGAA--KYFGQTILGGPFHII------------VITYACMILVTMV
MRLTSTTGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTEN------------
----PEN------------------LGQFYN------YPMSLFTTFELFLTIIDGP----
---ANYDVDLPFMYSVVYFAFAIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQIVAT
TVMLERKL--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DRWYL-----R---------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------
>ANAPL09262_HOG_0033281_Anasplatyrhynchos
------------------------------------QP----------------------
------------------------------------------------------------
--------------LLL----------------------------------DCR------
ICES-----------------------------------------P----------L---
-----LQAAKENNIPAIRKLLID---------------------------------GTCD
IYQR------------------GA--TGETALHVAALY---NSVEAAVALMEAAPE----
---------------------------------------LVNEKMTSELY----------
---------------------------EG--------------------------QTALH
IAAVNQNIALVKALLKRGANICTAQATGHFFRRSSQN-LLYF-GEHVLSFAACVGNEEIV
QLLIE---NGADIRAQDYLGNT-----VLHILVLQPNKT---------------------
--------FACH---------MYSLILSYDRN-KEGPGSLEL------------------
------IPNNEGLTPFKLAGVEGNTV-----------MFQYLMQK--------------R
K-HNLW------SFGPLTTVL-----YDLTEIDSWAE-----------------------
----------DQSFLELIVS-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDLTPVKELVSLKWNMYGRPYFCFLALFYVLY------MVCFTMCCVYRP
----LKAR-TG---NKT------SSR-DNTIYVQKMLQESYITYE-DELRLVGELITVIG
AVVILILEIPDILRVGAA--KYFGQTILGGPFHII------------VITYACMILVTMV
MRLTSTTGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTEN------------
----PEN------------------LGQFYN------YPMSLFTTFELFLTIIDGP----
---ANYDVDLPFMYSVVYFSFAVIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DRWYL-----RVEDRVDPNKHKMMRYTEAFKAHD----------
------------------RD--N--------------CDKGPEKLE--------------
------------------------------------IDSNILYKKEL--PA--L------
------SLSRN---------TSRMNSH-SGWE-----------------ILRRNTF-HSI
HGEVNHAM----------E--EEIG--MHFKL-------------------
>FICAL09711_HOG_0033281_Ficedulaalbicollis
-------MGVPL--------------------FGESNAFYSRIWNGLSQKL-------QG
KKS-WDKH-----------------------------------------------LD---
-----------EIYLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LQAAKENDLAAIRKLLTD---------------------------------GTCD
IYQR------------------GA--VGETALHVAAMY---DNLEAAVALMEAAPE----
---------------------------------------LINERMTSELY----------
---------------------------EG--------------------------QTALH
IAAANQNITLVKALLKRGANASTARATGHFFRRSSQN-LFYF-GEHVLSFAACVGNEEIV
QLLIE---NGADIRAQDSLGNT-----VLHILVLQPNKT---------------------
--------FACH---------MYSLILSYDRS-KEGPGSLEL------------------
------IPNNEGLSPFKLAGVEGNTV-----------MFQYLMQK--------------R
K-QNLW------SFGPLSTVL-----YDITEIDSWAE-----------------------
----------DQSFLELIVS-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDLTPVKELVSLKWNMYGRPYFCFLALFYILY------MVCFTMCCVYRP
----LKPR-TG---NRT------SSR-DNTVYVQKMLQESYVAYE-DELRLVGELITVIG
AVVILVLEIPDILRVGAA--KYFGQTILGGPFHII------------VITYACMILVTMV
MRLTSTTGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTEN------------
----PEN------------------LGQFYN------YPMSLFTTFELFLTIIDGP----
---ANYDVDLPFMYSVVYFAFAIIATLLMLNLLIAM-MGDTHWRVAHEQDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGREFGLG--------------
----------------DRWYL-----RIEDRIDPNKHKMMRYTEAFKAQD----------
------------------RE--S--------------YDKGSEKLE--------------
------------------------------------TNGDTLCKKDL--SALSL------
------SLSRS---------TSRTSSH-RGWE-----------------ILRRNTF-RQL
CGEVGPAV----------G--EEV-----YDV-------------------
>TAEGU00746_HOG_0033281_7a_Taeniopygiaguttata
-----------------------------------------------------------G
KKS-WDKH-----------------------------------------------LD---
-----------EIYLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LQAAKENNLAAIRKLLTD---------------------------------GTCD
IYQR------------------GA--VGETALHVAAMY---DNLEAAVALMEAAPE----
---------------------------------------LINERMTSELY----------
---------------------------EG--------------------------QTALH
IAAANQNTMLVKALLKRGANASTARATGHFFRRSSQN-LFYF-GEHVLSFAACVGNEEIV
QLLIE---NGADIRAQDSLGNT-----VLHILVLQPNKT---------------------
--------FACH---------MYSLILSYDRN-KEGPGSLEL------------------
------IPNNEGLSPFKLAGVEGNTV-----------MFQYLMQK--------------R
K-QNLW------SFGPLSTVL-----YDITEIDSWAE-----------------------
----------DQSFLELIVS-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDLTPVKELVSLKWNMYGRPYFCFLALFYILY------MVCFTMCCVYRP
----LKPR-TG---NRT------SSR-DNTVYVQKMLQESYVAYE-DELRLVGELITVIG
AVVILVLEIPDILRVGAA--KYFGQTILGGPFHII------------VITYACMILVTMV
MRLTSTTGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTEN------------
----PEN------------------LGQFYN------YPMSLFTTFELFLTIIDGP----
---ANYDVDLPFMYSVVYFAFAIIATLLMLNLLIAM-MGDTHWRVAHEQDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGREFGLG--------------
----------------DRWYL-----RIEDRVDPNKHKMMRYTEAFKAQD----------
------------------RD--N--------------YDKGSEKLE--------------
------------------------------------TNRDTLCKKEM--SA--L------
------SLSRS---------TSRTSSH-RGWE-----------------ILRRNT-----
---------------------------------------------------
>TAEGU14176_HOG_0033281_7b_Taeniopygiaguttata
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------IGNT-----VLHILVLQ-NKT---------------------
--------FACH---------MYSVILSYDRN-KEGPGSLEL------------------
------IPNNEGLSPFKLAGVEGNTV-----------MFQYLMQK--------------R
K-QNLW------SFGPLSTVL-----YDITEIDSWAE-----------------------
----------DQSFLELIVS-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDLTPVKELVSLKWNMYGRPYFCFLALFYILY------MVCFTMCCVYRP
----LKPR-TG---NRT------SSR-DNTVYVQKMLQESYVAYE-DELRLVGELITVIG
AVVILVLEIPDILRVGAA--KYFGQTILGGPFHII------------VITYACMILVTMV
MRLTSTTGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTEN------------
----PEN------------------LGQFYN------YPMSLFTTFELFLTIIDGP----
---ANYDVDLPFMYSVVYFAFAIIATLLMLNLLIAM-MGDTHWRVAHEQDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGREFGLG--------------
----------------DRWYL-----RIEDRVDPNKHKMMRYTEAFKAQD----------
------------------RD--N--------------YDKGSEKLE--------------
------------------------------------TNRDTLCKKEM--SA--L------
------SLSRS---------TSRTSSH-RGWE-----------------ILRRNT-----
---------------------------------------------------
>PELSI05074_HOG_0033281_9b_Pelodiscussinensis
-------LGFFV--------------------P--RIPG-LQI-----AKL-------SN
D---WEYN-----------------------------------------------LL---
-----------ASFTFK----------------------------------QRK------
IWES-----------------------------------------P----------L---
-----LQAAKENDLRAIKKLISD---------------------------------GTCD
VYQR------------------GA--VGETALHVAALY---DNTEVAQVLMEAAPD----
---------------------------------------LVNERMTSELY----------
---------------------------EG--------------------------QTALH
IAAVNQNINLVKALLKKGANVSSPRATGLFFRRSAQN-LIYF-GEHVLSFAACMGSEEIV
RLLIE---NGADIRAQDSLGNT-----VLHILVLQPNKT---------------------
--------FACQ---------MYNLLLSYDKS-DEGLGTLDS------------------
------IPNNEGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HTLW------SFGPVTSVL-----YDLTEIDSWGE-----------------------
----------DQSFLELVVS-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDLTPVKELVSLKWNMYGRPYFCFLALFYVLY------MICFTMCCVYRP
----LKAR-SE---NKT------NDR-DNTIYVQKMLQESYVIYE-DELRLVGELITVIG
AVVILILEIPDILRVGAT--KYFGQTILGGPFHVI------------IITYACMILVTMV
MRLTSTTGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFSS---AFYIIFQTED------------
----PAE------------------LGQFYS------YPMSLFTTFELFLTIIDGP----
---ANYSVDLPFMYSVVYFAFAVIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGQEYGLG--------------
----------------DRWYL-----RVEDRVDPNKHKMHRYTEAFKTQD----------
------------------KE--D--------------FDKCSEK----------------
------------------------------------LDEENPCKKDL--APVAP------
------SVSRS---------ISQSSSH-RGWE-----------------ILRRTTF-RQL
QGEVNYAM----------E--EEE----VYHV-------------------
>Chelonia_mydas_TRPV6_kel
-------MGLPL--------------------PGNSKPF-IQLWNRLRHKL-------QG
KKS-WARR-----------------------------------------------LD---
-----------EIHLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LQAAKENNLRAIKKLISD---------------------------------GTCD
VYQR------------------GA--VGETALHVAALY---DNMEAAQALMEAAPE----
---------------------------------------LVNERMTSELY----------
---------------------------EG--------------------------QTALH
IAAVNQNINLVKALLKKGANVSSPRATGLFFRRSAHN-LIYF-GEHVLSFAACMGSEEIV
RLLIE---NGADIRAQDSLGNT-----VLHILVLQPNKT---------------------
--------FACQ---------MYNLLLSYDKS-DGSLGTLDS------------------
------IPNSEGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HTLW------TFGPVTSVL-----YDLTEIDSWGE-----------------------
----------DQSFLELVVS-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDLTPVKELVSLKWNMYGHPYFCFLALFYVLY------MICFTMCCVYRP
----LKAR-TE---NKT------NDR-DNTIYVQKMLQESYVTYE-DELRLVGELITVIG
AVVILILEIPDILRVGAT--KYFGQTILGGPFHVI------------IITYACMILVTMV
MRLTSTTGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFSS---AFYIIFQTEN------------
----PTE------------------LGQFYS------YPMSLFTTFELFLTIIDGP----
---ANYNVDLPFMYSVVYFAFAVIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DRWYL-----RVEDRVDPNKQKMHRYTEAFKTQD----------
------------------KE--N--------------FDKYSEN----------------
------------------------------------LDGEIPYQKDL--APVAA------
------SVSRS---------TSQSSSH-RGWE-----------------ILRRTTF-RQL
QGEVNHAM----------E--EEE----VYHV-------------------
>Chrysemys_picta_bellii_TRPV6_Kel
-------MGLPL--------------------PGNSKPF-IQLWNMLRHKL-------QG
KKY-WARR-----------------------------------------------LD---
-----------EIHLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LQAAKENDLRAIKKLISD---------------------------------GTCD
VYQR------------------GA--VGETALHVAALY---DNMEAAQALMEAAPE----
---------------------------------------LVNERMTSELY----------
---------------------------EG--------------------------QTALH
IAAVNQNINLVKALLKKGANVSSPRATGLFFRRSAHN-LIYF-GEHVLSFAACMGSEEIV
RLLIE---NGADIRAQDYLGNT-----ILHILVLQPNKT---------------------
--------FACQ---------MYNLLLSYDKS-DGSLGTLDS------------------
------IPNNEGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HTLW------TFGPMTSVL-----YDLTEIDSWGE-----------------------
----------DQSFLELVVS-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDLTPVKELVSLKWNMYGHPYFCFLALFYVLY------MICFTMCCVYRP
----LKAR-SE---NKT------NDR-DNTIYVQKMLQESYVAYE-DELRLVGELITVIG
AVVILILEIPDILRVGAT--KYFGQTILGGPFHVI------------IITYACMILVTMV
MRLTSTTGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFSS---AFYIIFQTEN------------
----PTE------------------LGQFYS------YPMSLFTTFELFLTIIDGP----
---ANYSVDLPFMYSVVYFAFAVIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DRWYL-----RVEDRVDPNKQKMHRYTEAFKTQD----------
------------------KE--D--------------FDKHSEK----------------
------------------------------------LDGEFPYKKNL--APVAP------
------SVSRS---------TSQSSSH-RGWE-----------------ILRRTTF-RQL
QGEVNHAM----------E--EEE----VYHV-------------------
>Alligator_mississippiensis_TRPV6_Kel
-------MGVPL--------------------FGDSKLF-NQIWNGLCPRI-------QG
KKS-WDWC-----------------------------------------------LE---
-----------EIHLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LQAAKENDLRAIKKLLAD---------------------------------GSCD
VYQR------------------GA--VGETALHVAALY---DNVEVAQALLEAAPD----
---------------------------------------LINERMTSELY----------
---------------------------DG--------------------------QTALH
IAAVNQNVNLVKILLKKGANASAPRATGLFFRCSSHN-LIYF-GEHVLSFAACVGSEEIV
RLLIE---HGANIRAQDSLGNT-----ILHILVLQPNKT---------------------
--------FACQ---------MYNLILSYDKP-EEGLGSLES------------------
------IPNNEGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HTLW------SFGPITSVL-----YDLTEIDSCGE-----------------------
----------DQSFLELIVS-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDLTPVKELVNLKWNLYGRPYFCFLAFLYVLY------IICFTMCCVYRP
----LKAR-TS---NRT------SDR-DNTIYVQKMLQESYVTYE-DQLRLVGELVTVIG
AVVILILEIPDILRVGAT--KYFGQTILGGPFHVI------------IITYACMILMTMV
MRLTSTDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYVIFQTED------------
----PDR------------------LGQFYN------YAMSLFTTFELFLTIIDGP----
---ANYDVDLPFMYSVVYFAFAIIATLLMLNLFIAM-MGDTHWRVANERDELWRAQIVAT
TVMLERKL--------PR-----------CLWPR-SGICGREFGLS--------------
----------------DCWYL-----RVEDRVDPNKHKMFRYADAFKSQE----------
------------------KE--E--------------CDKYSEKLE--------------
------------------------------------LDEEFPCKRNL--TPSAS------
------SVSRS---------TTRSSSH-RGWQ-----------------ILRRSTF-SQF
CGEINPSM----------E--EEV-----YHV-------------------
>Alligator_sinensis_TRPV6_Kel
-------MGVPL--------------------FGDSKLF-NQIWNGLCPRI-------QG
KKS-WDWC-----------------------------------------------LE---
-----------EIHLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LQAAKENDLRAIKKLLAD---------------------------------GSCD
VYQR------------------GA--VGETALHVAALY---DNVEVAQALLEAAPD----
---------------------------------------LINERMTSELY----------
---------------------------DG--------------------------QTALH
IAAVNQNINLVKILLKKGANASAPRATGLFFRCSSHN-LIYF-GEHVLSFAACVGSEEIV
RLLIE---HGANIRAQDSLGNT-----ILHILVLQPNKT---------------------
--------FACQ---------MYNLILSYDKP-EEGLGSLES------------------
------IPNNEGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HTLW------SFGPITSVL-----YDLTEIDSCGE-----------------------
----------DQSFLELIVS-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDLTPVKELVNLKWNLYGRPYFCFLAFLYVLY------IICFTMCCVYRP
----LKAR-TS---NRT------SDR-DNTIYVQKMLQESYVTYE-DQLRLVGELVTVIG
AVVILILEIPDILRVGAT--KYFGQTILGGPFHVI------------IITYACMILMTMV
MRLTSTDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYVIFQTED------------
----PDR------------------LGQFYN------YAMSLFTTFELFLTIIDGP----
---ANYDVDLPFMYSVVYFAFAIIATLLMLNLFIAM-MGDTHWRVANERDELWRAQIVAT
TVMLERKL--------PR-----------CLWPR-SGICGREFGLS--------------
----------------DCWYL-----RVEDRVDPNKHKMFRYADAFKSQE----------
------------------KE--E--------------CDKYSEKLE--------------
------------------------------------LDEEFPCKRNL--TPSAS------
------SVSRS---------TTGSSSH-RGWQ-----------------ILRRSTF-SQF
RGEINPSM----------E--EEV-----YHV-------------------
>Gavialis_gangeticus_XP_019383221.1
-------MGVPL--------------------FGDSKLF-SQIWNRLCHRI-------QG
KKS-WDWC-----------------------------------------------LE---
-----------EIHLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LQAAKENDLQAIKKLLAD---------------------------------GSCD
VYQR------------------GA--VGETALHVAALY---DNVEVAQALLEAAPD----
---------------------------------------LVNERMTSELY----------
---------------------------DG--------------------------QTALH
IAAVNQNVNLVKILLKKGANASTPQATGLFFRCSSHN-LIYF-GEHVLSFAACVGSEEIV
RLLIE---HGASIRAQDSLGNT-----ILHILVLQPNKT---------------------
--------FACQ---------MYNLILSYDKP-EEGLGSLES------------------
------IPNNEGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HTLW------SFGPITSVL-----YDLTEIDSCGE-----------------------
----------DQSFLELIVS-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDLTPVKELVNLKWNLYGRPYFCFLAFLYVLY------IICFTMCCVYRP
----LKAR-TS---NRT------SDR-DNTIYVQKMLQESYVTYE-DQLRLVGELVTVIG
AVVILTLEIPDILRVGAT--KYFGQTILGGPFHVI------------IITYACMILMTMV
MRLTSTDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYVIFQTED------------
----PDR------------------LGQFYD------YAMSLFTTFELFLTIIDGP----
---ANYDVDLPFMYSVVYFAFAIIATLLMLNLFIAM-MGDTHWRVANERDELWRAQIVAT
TVMLERKL--------PR-----------CLWPR-SGICGREFGLS--------------
----------------DCWYL-----RVEDRVDPNKHKMFRYADAFKSQE----------
------------------KE--D--------------CDKYSEKLE--------------
------------------------------------LDEEFPCKRNL--TPSAS------
------SVSRS---------TTRSSSH-RGWQ-----------------ILRRSTF-SQF
RGEINPST----------E--EEV-----YHV-------------------
>Crocodylus_porosus_XP_019404056.1
-------MGVPL--------------------FGDNKLL-KQIWNGLCHRV-------QG
KKS-RDWR-----------------------------------------------LE---
-----------EIHLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LQAAKENDLQAIKKLLAD---------------------------------GSCD
VYQR------------------GA--VGETALHVAALY---DNMEVAQALLEAAPD----
---------------------------------------LVNERMTSELY----------
---------------------------DG--------------------------QTALH
IAAVNQNVNLVKILLKKGANASAPRATGLFFRCSSHN-LIYF-GEHVLSFAACVGSEEIV
RLLIE---HGANIRAQDSLGNT-----ILHILVLQPNKT---------------------
--------FACQ---------MYNLILSYDKP-EEGLGSLES------------------
------IPNNEGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HTLW------SFGPITSVL-----YDLTEIDPCGE-----------------------
----------DQSFLELIVS-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDLTPVKELVNLKWNLYGRPYFCFLAFLYVLY------IICFTMCCVYRP
----LKAR-TS---NRT------SDR-DNTIYVQKMLQESYVTYE-DQLRLVGELVTVIG
AVVILILEIPDILRVGAT--KYFGQTILGGPFHVI------------IITYACMILMTMV
MRLTSTDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYVIFQTED------------
----PDR------------------LGQFYD------YAMSLFTTFELFLTIIDGP----
---ANYDVDLPFMYSVVYFAFAIIATLLMLNLFIAM-MGDTHWRVANERDELWRAQIVAT
TVMLERKL--------PR-----------CLWPR-SGICGREFGLS--------------
----------------DCWYL-----RVEDRVDPNKHKMFRYADAFKSQE----------
------------------KE--D--------------CDKYSEKLQ--------------
------------------------------------LDEEFPCKRHL--TPSAS------
------SVSRS---------TTRSSSH-RGWQ-----------------ILRRSTF-SQF
RGEINPST----------E--EEV-----YHV-------------------
>Gekko_japonicus_XP_015275289.1
-------MGVPV--------------------PGENGLL-GALWKRLSCRVV-GAGCSRG
GGG-RRCS-----------------------------------------------LD---
-----------EMHLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LLAAKENNVQGIRKLTMD---------------------------------GSCD
VYQR------------------GV--VGETALHVAALY---DGTEAAEALMEVAPE----
---------------------------------------LVNERMTSELY----------
---------------------------EG--------------------------QTALH
IAAINQNVNLVKSLIRKGAHISTPRATGLFFRRSSKN-LFYF-GEHILSFAACMGNEEIV
QLLIA---NGADIRAQDSLGNT-----ILHILVLQPNRN---------------------
--------FACQ---------MYNLLLSFEKR-AGGLAPLES------------------
------IPNNDGLTPFKLAGVEGNSV-----------LFHHLLQK--------------R
K-HVLW------SFGPLTTIL-----YDLTEIDSWGE-----------------------
----------DQPFLELVVS-TKRRE----------------------------------
------------------------------------------------------------
------ARQILDMTPVKELVSLKWNTYGRPYFCFLGLFYILY------MICFTTCCSYRP
----LKER-PD---NHT------DER-DNAILIQKTLQESYLTYD-DWLRLVGELITVIG
ALAILLLEIPDVLRVGFT--KYFGQTILGGPFHII------------IITYACMILVTMV
MRLTSTDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCGLMAVVILGFAS---AFYIIFQTEN------------
----PSA------------------LGQFYS------YPMSLFSTFELFLTIIDGP----
---ANYDVDLPFMYSVVYFAFAIIAALLMLNLLIAM-MGDTHWRVASERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DRWYL-----RVEDRVDAKKQKMSRYAKAFKSHG----------
------------------KE--D--------------PEKLSVKLE--------------
------------------------------------PYEGFQFRDGP--SP---------
------SVSRS---------TSQSSSH-RGWH-----------------ILRNSTF-SRL
RGEVNHAL----------E--EEV-----YHI-------------------
>Anolis_lizard_ANOCA14245_TRPV5
-------MGVPF--------------------PREQGPF-GALWKRMSRGW---KPQERP
TPG-ARRG-----------------------------------------------LD---
-----------EMHLSQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LLAAKENDVQAIRKLTMD---------------------------------GSCD
LFQR------------------GA--VGETALHIAALY---NNENAAEALLEVAPE----
---------------------------------------LINEKMTSELY----------
---------------------------EG--------------------------QTAMH
IAAANQNVNLVKCLLKKGAHISTPRATGLFFRRSTQS-LFYF-GEHVLSFAACAGSEEIV
GLLIE---NGADIRAQDSLGNT-----ILHILVLQPNRI---------------------
--------FACH---------MYNLLLSYDRH-EGGLGPMDS------------------
------ITNNEGLTPFKLAGIEGNTV-----------MFQHLMQK--------------R
R-HRLW------SFGPITTVF-----YDLTEIDSWGE-----------------------
----------EQPFLELVVS-TKKRE----------------------------------
------------------------------------------------------------
------ARHILDITPVKELVSLKWNTYGRPYFCFLALFYVLY------MICFTMCCVYRP
----LKYR-LE---NRT------NTR-DTRVLLQKTLQESYVTYE-DQLRLVGELITVIG
ALAILLLEIPDILRIGAA--KFFGQTILGGPFHII------------IITYSCMILVTMV
MRLTSTDGEVAPMSCALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCGLMAVVILGFAS---AFYIIFQTED------------
----SSK------------------LGQFYD------YPMSLFTTFELFLTIIDGP----
---ANYDVDLPFMYSVVYFAFAIIAALLMLNLLIAM-MGDTHWRVANERDDLWRAQVVAT
TIMLERKL--------PR-----------CLWPR-SGICGQEYGLG--------------
----------------DKWFL-----RVEERLDSSKHKVLRYADIFRNQD----------
------------------KE--D--------------LDKFSGKLR--------------
------------------------------------LSDHSQFKKET--SP---------
------SVSRS---------TSQSSSH-RGWQ-----------------ILRDNTF-NRF
CGEVNHAL----------E--EEV-----YHV-------------------
>Chinese_turttle_XM_006111855
------------------------------------------------------------
-------------------------------------------------------MD---
------------------------------------------------------------
-WVE-----------------------------------------N----------L---
-----LQGKK------------------------------------------------C-
--QR--------------------------------------------------------
-----------------------------------------------KWYWL--------
---------------------------IG--------------------------ETALH
IAVVNKNFRLVKVMLEMGADVNKPRATGYVFRSNGHN-LMYF-GEHILSFAACAGSEAIV
RLLIK---HGANIRAQDTLGNT-----VLHILVLQPNKT---------------------
--------IACQ---------MYNFLLSHDKS-ESELGALDL------------------
------IPNNEGLTAFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HIQW------TFGPLVSTL-----YDLTEIDSWGD-----------------------
----------DQSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------ARRILDLTPVNELVSLKWNKYGRPYFCILAFFYVLY------MICFTMCCVYRP
----LKHR-QS---NKT------HER-DNTIYIQKQLQESYVTPE-DNLRLVGELITVIG
AMVILILEIPDIFRVGIT--KYFGQTILGGPFHVI------------IITYACMILVTMV
MRLTSTTGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYVIFQTEN------------
----PDE------------------LGHFYN------YPMALFSTFELFLTIIDGP----
---ANYEVDLPFMYGITYSAFAVIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQIVAT
TVMLERKL--------PQ-----------CLWPR-SGICGKEYGLG--------------
----------------DSWYL-----RVESRCEGRQHKMHRYMEVLKSQN----------
------------------TE--D--------------FDKYSQNKQE-------------
--------------------------------LED-KDMVAPYRKKT--PCSTP------
------AVSPS---------LSRRSSN-RGWE-----------------ILRHSTI-GQL
RHPANLAM----------E--EEEAEE-VYHV-------------------
>Chelonia_mydas_TRPV6
-------MGMFL--------------------PGDHGLL-LGLWNSLLHRF-------QT
EKS-WTRR-----------------------------------------------LD---
-----------EISLLQ----------------------------------QKR------
IWES-----------------------------------------S----------L---
-----LQAAKENDVQTIQKLLTC---------------------------------HTCD
IHQR------------------GA--LGETALHVAALY---DSVEAAQMLMDAAPE----
---------------------------------------LVNEAMTSEFY----------
---------------------------AG--------------------------ETALH
IAVVNKNFKLVKAMLEKGADVNNPQATGYVFRLSSHN-LIYF-GEHILSFAACVGSEEIV
RLLIK---HGANIRAQDSLGNT-----VLHILVLQPNKI---------------------
--------FACQ---------MYNFLLSYDKS-ERELGALDL------------------
------IPNNKGLTPFKLAGVEGNTV-----------MFQHLMQN--------------R
K-HIQW------TFGPLVSTL-----YDLTEIDSWGD-----------------------
----------DQSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------ARRILDLTPVNELVSLKWNKYGRPYFCILALFYVLY------MICFTMCCVYRP
----LKRR-QS---NKT------HER-DNTIYVQKLLQESYVTPE-DNLRLVGELITVIG
AIVILILEIPDIFRVGVT--KYFGQTILGGPFHII------------IITYACMILVTMV
MRLTSTTGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYVIFQTEN------------
----PDE------------------LGHFYN------YPIALFSTFELFLTIIDGP----
---ANYEVDLPFMYGITYSAFAVIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PQ-----------CLWPR-SGICGLEYGLG--------------
----------------DHWYL-----RVEDRCEGRQHKMHRYMEAFKSQI----------
------------------TE--D--------------FDKYSQKKQE-------------
--------------------------------LEDEKDMEAPYRKKT--PCSTP------
------AVSPS---------LSRRSSS-HGWD-----------------ILRHSTL-GQL
YGHVNLAM----------E--KE--EE-VYHV-------------------
>Chrysemys_picta_bellii_TRPV6
-------MGMFL--------------------PGDHGLL-LGLWNSLLRRF-------QS
EKS-WTRR-----------------------------------------------LD---
-----------EINLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LQAAKENDVQTIQRLLTC---------------------------------HTCD
IHQR------------------GA--LGETALHVAALY---DSMEAAQILMDAAPE----
---------------------------------------LVNEAMTSEFY----------
---------------------------AG--------------------------ETALH
IAVVNKNFKLVKAMLEKGADVNNPRATGYVFRPSSHN-LIYF-GEHILSFAACVGSEEIV
QLLIK---HGANIRAQDTLGNT-----VLHILVLQPNKI---------------------
--------FACQ---------MYNFLLSYDKS-ERELGALDL------------------
------IPNNEGLTPFKLTGVEGNTV-----------MFQHLMQN--------------R
K-HIQW------TFGPLVSTL-----YDLTEIDSWGD-----------------------
----------DQSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------ARRILDLTPVNELVSLKWNKYGRPYFCILALFYVLY------MICFTMCCVYRP
----LKRR-QS---NKT------HER-DNTIYIQKLLQESYATPE-DNLRLVGELITVIG
AIVILILEIPDIFRVGVT--KYFGQTILGGPFHII------------IITYACMILVTMV
MRLTSTTGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYVIFQTEN------------
----PDE------------------LGHFYN------YPIALFSTFELFLTIIDGP----
---ANYEVDLPFMYSITYSAFAVIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PQ-----------CLWPR-SGICGQEYGLG--------------
----------------DRWYL-----RVEDRCEGRQHKMHRYMEAFKFQI----------
------------------TE--D--------------FDKYSQNKQE-------------
--------------------------------LEDDKDTEAPYRKKT--PCSTP------
------AVSPS---------LSRRSSS-HGWD-----------------ILRHSTL-GQL
QGHVNLPM----------E--KE--EE-IYHV-------------------
>Alliator_sinensis_TRPV6
-------MGMFL--------------------PRKHGLL-LRLWSSLLRSL-------QG
EKS-WARR-----------------------------------------------LD---
-----------EINLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LRAAKENDVQAIQKLLAC---------------------------------SASD
IHQR------------------GA--TGETALHVAALY---DNVEAAQILMDAAPD----
---------------------------------------LINEAMTSELY----------
---------------------------AG--------------------------ETALH
IAVVNKNFSLVKAMLDKGADINNLRATGYVFRHSSHN-LIYF-GEHILSFAACGGSEEIV
RLLIE---NGADIRAQDALGNT-----ILHILVLQPNKN---------------------
--------FACQ---------MYNLILSYDKG-GGGLEALDL------------------
------IPNNEGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HIQW------TFGPLTSTL-----YDLTEIDSWGD-----------------------
----------DLSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------ARRILDLTPVTELVSLKWNKYGRPYFCILALFYVLY------MICFTMCCVYRP
----LKQR-YS---NKT------DER-DNTIYIQKMLQESYVTPE-DDVRLVGELITVIG
AIVILILEIPDIFRVGAT--KYFGQTILGGPFHII------------IITYACMILVTMV
MRLTSTNGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTQD------------
----PDE------------------LGHFYN------YPMALFSTFELFLTIIDGP----
---ANYEVDLPFMYGITYSAFAVIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PQ-----------CLWPR-SGICGREYGLG--------------
----------------DRWYL-----RVEDRRDDKQHKMHRYAAAFTTQV----------
------------------TE--D--------------FDKYSENKTE-------------
--------------------------------LEDSGHIKGSYMKKL--SHFMP------
------SVSPT---------PSQRSSN-RGWE-----------------ILRHSTF-GKL
QGHVNLVM----------E--KEDEEEEVYHV-------------------
>Alligator_mississippiensis_TRPV6
-------MGMFL--------------------PGKHGLL-LRLWSSLLRSL-------QG
EKS-WARR-----------------------------------------------LD---
-----------EINLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LRAAKENDVQAIQKLLAC---------------------------------SASD
IHQR------------------GA--TGETALHVAALY---DNVEAAQILMDAAPD----
---------------------------------------LINEAMTSELY----------
---------------------------AG--------------------------ETALH
IAVVNKNFSLVKAMLDKGADINNPRATGYVFRHSSHS-LIYF-GEHILSFAACGGSEEIV
RLLIE---NGADIRAQDALGNT-----ILHILVLQPNKN---------------------
--------FACQ---------MYNLILSYDKG-GGGLEALDL------------------
------IPNSEGLTAFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HIQW------TFGPLTSTL-----YDLTEIDSWGD-----------------------
----------DLSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------ARRILDLTPVTELVSLKWNKYGRPYFCILALFYVLY------MICFTMCCVYRP
----LKQR-YS---NKT------DER-DNTIYIQKMLQESYVTPE-DDVRLVGELITVIG
AIVILILEIPDIFRVGAT--KYFGQTILGGPFHII------------IITYACMILVTMV
MRLTSTNGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTQD------------
----PDE------------------LGHFYN------YPMALFSTFELFLTIIDGP----
---ANYEVDLPFMYGITYSAFAVIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PQ-----------CLWPR-SGICGREYGLG--------------
----------------DRWYL-----RVEDRRDDKQHKMHRYAAAFTTQV----------
------------------TE--D--------------FDKYSENKTE-------------
--------------------------------LEDSGHIKGSYMKKL--SHFMP------
------SVSPT---------PSQRSSN-RGWE-----------------ILRHSTF-GKL
QGHVNLAM----------E--KEDEEEEVYHV-------------------
>Crocodylus_porosus_XP_019404058.1
-------MGMFL--------------------PGKHGLL-LRLWNSLLRSL-------QG
EKS-WARR-----------------------------------------------LD---
-----------EINLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LRAAKENDVQAIQKLLAC---------------------------------SASD
IHQR------------------GA--TGETALHVAALY---DNVEAAQILMDAAPD----
---------------------------------------LINEAMTSELY----------
---------------------------AG--------------------------ETALH
IAVVNKNFSLVKAMLDKGADINNPQATGYVFRRSSHN-LIYF-GEHILSFAACGGSEEIV
RLLIE---NGADIRAQDALGNT-----ILHILVLQPNKN---------------------
--------FACQ---------MYNLILSYDKG-GGGLEALDL------------------
------IPNNEGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HIQW------TFGPLTSTL-----YDLTEIDSWGD-----------------------
----------DLSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------ARRILDLTPVTELVSLKWNKYGRPYFCILALFYVLY------MICFTMCCVYRP
----LKQR-YS---NKT------DER-DNTIYIQKILQESYVTPE-DDVRLVGELITVIG
AIVILILEIPDIFRVGAT--KYFGQTILGGPFHII------------IITYACMILVTMV
MRLTSTNGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTQD------------
----PDE------------------LGHFYN------YPMALFSTFELFLTIIDGP----
---ANYEVDLPFMYGITYSAFAVIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PQ-----------CLWPR-SGICGREYGLG--------------
----------------DRWYL-----RVEDRRDDKQHKMHRYAAAFTTQV----------
------------------TE--D--------------FDKYSENKTE-------------
--------------------------------LEYSGHIKGSYMKKL--SHCTP------
------SVSPA---------LSQRSSN-RGWE-----------------ILRHSTF-GKL
QGHVNLAM----------E--KEDEEEEVYHV-------------------
>Gavialis_gangeticus_XP_019383237.1
-------MGMFL--------------------PGKHGLL-LRLWNSLLRSL-------QG
EKS-WARR-----------------------------------------------LD---
-----------EINLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LRAAKENDVQAIQKLLAC---------------------------------SASD
IHQR------------------GA--TGETALHVAALY---DNVEAAQILMDAAPD----
---------------------------------------LINEAMTSELY----------
---------------------------AG--------------------------ETALH
IAVVNKSFSLVKAMLDKGADINNPQATGYVFRRSSHN-LIYF-GEHILSFAACGGSEEIV
RLLIE---NGADIRAQDALGNT-----ILHILVLQPNKN---------------------
--------FACQ---------MYNLILSYDKG-GGGLEALDL------------------
------IPNNEGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HIQW------TFGPLTSTL-----YDLTEIDSWGD-----------------------
----------DLSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------ARRILDLTPVTELVSLKWNKYGRPYFCILALFYVLY------MICFTMCCVYRP
----LKQR-YS---NKT------DER-DNTIYIQKMLQESYVTPE-DDVRLVGELITVIG
AIVILILEIPDIFRVGAT--KYFGQTILGGPFHII------------IITYACMILVTMV
MRLTSTNGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTQD------------
----PDE------------------LGHFYN------YPMALFSTFELFLTIIDGP----
---ANYEVDLPFMYGITYSAFAVIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PQ-----------CLWPR-SGICGREYGLG--------------
----------------DRWYL-----RVEDRRDDKQHKMHRYAAAFTTQV----------
------------------TE--D--------------FDKYSENKTE-------------
--------------------------------LEYSGHIKGSYMKKL--SHCTP------
------SVSPA---------LSQRSSN-RGWE-----------------ILRHSTF-GKL
QGHVNLAM----------E--KEDEEEEVYHV-------------------
>Python_bivittatus_TRPV6
-------MGVPL--------------------PDAKGRL-GALWKRLSCSLRTLIQTKGG
QQS-W---------------------------------------------------D---
-----------EIHLLQ----------------------------------LKR------
IWES-----------------------------------------P----------L---
-----LLAAKENNIQALRKLIQD---------------------------------GSCD
IYQR------------------GA--TGETALHVATLY---DCTEAADFLLEVAPE----
---------------------------------------LINEKITSALY----------
---------------------------EG--------------------------ETALH
IAAVNQNVHLVKCLLKKGAHISIPRATGHFFRRNSSN-PFYF-GEHVLSFAACMGNEEIV
RLLIE---NGADIRAQDSLGNT-----VLHILVLQPNRT---------------------
--------FACQ---------MYNLILSYDKQ-EGNLEPLDL------------------
------IPNNEGLTPFKLAGVEGNIV-----------MFQHLLQK--------------R
K-QIMW------SLGPITTIL-----YDLTEIDSWGE-----------------------
----------DQSFLELVVS-TKKKE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------
>Thamnophis_sirtalis_TRPV6_2
-------MGVPV--------------------PGANGRL-GALWKRLNPGLRLLIQTKDG
RQS-W---------------------------------------------------D---
-----------EIHLLH----------------------------------LKR------
IWES-----------------------------------------P----------L---
-----LLAAKENNVQGLRKLIED---------------------------------GSCD
IYQR------------------GA--IGETALHVATLH---DCTEAADFLLEVAPE----
---------------------------------------LINEKMTSTLY----------
---------------------------EG--------------------------QTALH
IAAVNQNVHLVKCLLKKRAHISTPRATGHFFRRNSSH-HSYF-GEHVLSFAASVGNEEIV
RLLIE---NGADIRAQDSLGNT-----VLHILVLQPNRT---------------------
--------FACQ---------MYNFILSYDKQ-EGNLEALDL------------------
------IPNNEGLTPFKLAGVEGNIV-----------MFQHLLQK--------------R
K-QIMW------SLGPITTIL-----YDLTEIDSWGE-----------------------
----------DQSFLELVVS-TKKRE----------------------------------
------------------------------------------------------------
------ARRILDITPVKELVNLKWNTYGRPYFCFLALFYVLY------MICFTMCCVYRP
----LKSR-SE---NQT------NKR-DNTIIVQKTLQESYLTYE-DQLRLVGELITVIG
AMAILLLEIPDILRVGAT--KYFGQTILGGPFHII------------IITYACVILVTMA
MRLTSTEGEVVPMSIALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLIRFCGLMAVVILGFAS---AFYIIFQTEN------------
----PSN------------------LGQFYN------YPMSLFSTFELFLTIIDGP----
---ANYDVDLPFVFCVVYAAFAIIAALLMLNLLIAM-MGDTHWRVANERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGQEYGLG--------------
----------------DKWFL-----RVEERLDISKHKMLRYAEAFRNQD----------
------------------KE--V--------------FDKYSGKLY--------------
------------------------------------QPEPFQFKKET--P--SP------
------SVSRS---------STLSSFH-RGWQ-----------------ILRNNTF-SHL
RGEVNHAL----------E--EEI-----YHF-------------------
>Protobothrops_mucrosquamatus_XP_015670835.1
-------MGVPV--------------------PGANGRL-GAVWKRLSRSLRPLVPTKGG
RQS-W---------------------------------------------------D---
-----------ELHLLH----------------------------------LKR------
IWES-----------------------------------------P----------L---
-----LLAAKDNNVQGLRKLIQD---------------------------------GSCD
IYQR------------------GA--IGETALHVATLY---DCTEAADFLLEVAPE----
---------------------------------------LINEKMTSALY----------
---------------------------EG--------------------------QTAFH
IAAVNQNVHLVKCLLKKRAHISTPRATGHFFRRNSSH-RSYF-GEHILSFAASVGNEEIV
RLLIE---NGADIRAQDSLGNT-----VLHILVLQPNRT---------------------
--------FACQ---------MYNLILSYDKQ-EGNLEPLDL------------------
------IPNNEGLTPFKLAGVEGNTV-----------MFQHLMQT--------------R
K-QIMW------SLGPITTIL-----YDLTEIDSWGE-----------------------
----------NQSFLELVVS-TKKRE----------------------------------
------------------------------------------------------------
------ARRILDITPVKELVNLKWNTYGRPYFCFLALFYVLY------MICFTMCCVYRP
----LKNR-SD---NQT------DER-DNTIIVQKTLQESYLTYE-DQLRLVGELITVIG
AMAILLFEIPDILRVGAT--KYFGQTILGGPFHII------------IITYACVILIIMV
MRLTSTEGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLIRFCGLMAVVIFGFAS---AFYIIFQTEN------------
----PSN------------------LGEFYN------YPMSLFSTFELFLTIIDGP----
---ANYDVDLPFVFCVVYAAFAIIAALLMLNLLIAM-MGDTHWRVANEQDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGQEYGLG--------------
----------------DRWFL-----RVEERLDVSKHKMLRYAEAFKNQD----------
------------------KE--D--------------FDRFSRKLY--------------
------------------------------------QPERFQFKKET-----SP------
------SVSRS---------TTLSSFH-RGWQ-----------------ILRNNTL-SHL
HGEANHAL----------E--DEI-----YHV-------------------
>Anolis_lizard_ANOCA13121_TRPV6
-------MGMLLLLL----------------PSGERGFL-GRLWTALLRWL-------QG
DKS-WARK-----------------------------------------------LD---
-----------ESSLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LLAARENDVSTIQKLLAS---------------------------------HSCD
LHER------------------GA--VGETALHVAALH---NSLEVAQLLLETAPE----
---------------------------------------LVDETMTSELY----------
---------------------------KG--------------------------ETALH
IAVVNKNVSLVKVLLEKGADINGPRATGYVFRPRSDN-LIYF-GEHILSFAACAGSEDIV
KLLIE---HGANIRVQDSFGNT-----VLHILVLQPNKA---------------------
--------SACQ---------MYNLFLCYNKQ-DKELMDLDS------------------
------IPNNEGLTPFKLAGVEGNTV-----------MFQHLMQR--------------R
K-HIQW------TFGPVTSTL-----YDLTEIDSWAD-----------------------
----------DQSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------ARRILDLTPVNELVSLKWNKYGRPYFCVLAFFYVLY------MICFTMCCVYRP
----LKLR-TG---NKT------YER-DNTIYVQKLLQESYLTPE-DDLRLVGELITVIG
AIVILILEIPDIVRVGIA--KYFGQTILGGPFHVI------------IITYACMILLTMV
MRLTSTQGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLLRFCWLMAVVILGFAS---AFYVIFQTED------------
----PDE------------------LGHFYN------YPMALFSTFELFLTIIDGP----
---ANYEVDLPFMYGITYSAFAVIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGKEYGLG--------------
----------------DRWYL-----RVEHRYEIRQQKNRLSAKKYDLHR----------
------------------RD--A--------------FEKYLKAKMT-------------
--------------------------------PGGEYGREAHSTKQG--PFGSA------
------SSTPD---------SSRRSTN-FGWD-----------------VLRCNAR-L--
QGYTNHAM----------E--EEE----VYHV-------------------
>Python_bivittatus_TRPV6_Ephrin
-------MGMLP--------------------PGDRGFF-PGLWATLLRRL-------RG
EKS-WARK-----------------------------------------------LD---
-----------ETNLLQ----------------------------------QKR------
ICES-----------------------------------------P----------L---
-----LLAAKENDASAIRKLVAS---------------------------------HTCD
LHER------------------GA--VGETALHVAALY---NNLEAAQLLISAAPE----
---------------------------------------LVNEPVTSELY----------
---------------------------AG--------------------------ETALH
IAVINKNLDLVKALLEKGADINGPRATGYVFRRRSDS-LFYF-GEHILSFAACAGNEAIV
QLLIE---HGANIQVQDSLGNS-----VFHILALQPNKV---------------------
--------SACQ---------IYDLLLCYGKK-EKGLGDLDA------------------
------VLNYEGLTPFKLAGVEGNTL-----------MFQHLMQR--------------K
K-HILW------TLGPLTSTL-----YDLTEIDSWGD-----------------------
----------DQSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------ARRILDLTPVNELVSLKWNKYGRPYFCILALFYVLY------MICFTMCCVYRP
----LKER-SC---NRT------NER-DNTIYVQKLLQESYITPE-DNHRLVGELITVVG
AIVILILEIPDIFRFGVT--KYFGQTILGGPFHAI------------IILYACMILLTMV
MRLTSTNGEVVPMSLALVLGWCNIMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLLRFCWLMVVVILGFAS---AFYIIFQTED------------
----PDK------------------LGHFYS------YPMALYSTFQLFLTIIDGP----
---ANYEVDLPFMYGITYSAFAVIAALLMLNLLIAM-MGDTHWRVAHERDELWRAQVVST
TIMLERKL--------PQ-----------CLWPR-LGICGKEYGLG--------------
----------------DQRYL-----RIEDRCEIRQ----TCIKTNGPYR----------
------------------RD--A--------------FEKYLQRKQTQ--D---------
------------------------------VAADGKVGRPILSKEEK--DISPP------
------SNTVN--------------AN-GHWD-----------------ILRQSML-IQK
KGYTNHAM---------EE--EEE----VYHV-------------------
>Protobothrops_mucrosquamatus_XP_015670836.1
-------MGMLL--------------------PGDRGFF-PGLWAALLRRI-------RG
EKS-WARK-----------------------------------------------LD---
-----------ETNLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LLAAKENDLSAIQKLIAS---------------------------------HTCD
LHER------------------GA--VGETALHVAALY---NNLEAAQLLINAVPE----
---------------------------------------LVNEPVTSELY----------
---------------------------AG--------------------------ETALH
IAVVNKNLGLVKALLEKGADVNGPRATGYVFRRRNDS-LFYF-GEHILSFAACAGSEAIV
QLLIE---HGANIRVQDSLGNS-----VFHILTLQPNKA---------------------
--------SACQ---------IYDLLHCYDKK-EKGLGDLDA------------------
------ILNYEGLTPFKLAGVEGNTV-----------MFNHLMQR--------------K
K-HVLW------NFGSLKSTL-----YDLTEIDSWGD-----------------------
----------DQSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------ARRILDLTPVNELVSLKWNKYGRPYFCILAVFYVLY------MICFTMCCVYRP
----LKER-SC---NKT------NER-DNTIYVQKLLQESYITSE-DNHRLVGELITIVG
AIVILILEIPDIFRFGIT--KYFGQTILGGPFHAI------------IIVYACMILLTMV
MRLTSTNGEVVPMSLALVLGWCNIMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLLRFCWLMVVVILGFAS---AFYIIFQTED------------
----PNE------------------LGHFYS------YPMALYSTFQLFLTIIDGP----
---ANYEVDLPFMYGITYSAFAIIAALLMLNLLIAM-MGDTHWRVAHERDELWRAQVVST
TIMLERKL--------PQ-----------CLWPR-LGICGKEYGLG--------------
----------------NQRYL-----RVEDRCEIRQ----MSVKTNGPYR----------
------------------RD--A--------------FEKYLQRKQTQ--D---------
------------------------------VAAEGKDGGPILSKQQK--YVGAP------
------SNTAN--------------TN-SHWN-----------------ILRQSTL-VHK
QGYTNHAM----------E--EEEEEE-VYHV-------------------
>Thamnophis_sirtalis_TRPV6
-------MGMLL--------------------PGDRGFF-PRLWAALLHRI-------RG
EKS-WARK-----------------------------------------------LD---
-----------ETNLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LLAAKENDLSAIQKLIES---------------------------------HSCD
LHER------------------GA--VGETALHVAALH---NNLEAAQLLINAAPE----
---------------------------------------LVNEPVTSELY----------
---------------------------AG--------------------------ETALH
IAVVNKNLGLVKALLVKGADINGPRATGYVFKRRNDS-LFYF-GEHILSFAACAGSETIV
QLLIE---NGAKIRVQDSLGNS-----IFHILTLQPNKV---------------------
--------SACQ---------IYDLLFCYDKK-EKGLGDPDA------------------
------VFNYEGLTPFKLAGAEGNTV-----------MFSHLMQR--------------R
K-HILW------TFGSLTSTL-----YDLTEIDSWGD-----------------------
----------DQSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------ARRILDLTPVNELVSLKWNKYGRPYFCILALFYVLY------MICFTMCCVYRP
----LKER-SF---NKT------NER-DNTIYVQKHLQESYITSE-DNHRLVGELITVVG
AIVILILEIPDIFRFGIT--KYFGQTILGGPFHAI------------IIVYACMILLTMV
MRLTSTNGEVVPMSLALVLGWCNIMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLLRFCWLMAVVILGFAS---GCF-------------------
----------------------------HYH------Y----------------------
----------------------------------------------------VRAQTPTV
SLASLRHL--------WK-----------GIWPR--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------
>HUMAN25987_HOG_0033281_3b_1a_Homosapiens
-------MGLSL--------------------PKEKGLI-LCLWSKFCRWF-------QR
RES-WAQS-----------------------------------------------RD---
-----------EQNLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LLAAKDNDVQALNKLLKY---------------------------------EDCK
VHQR------------------GA--MGETALHIAALY---DNLEAAMVLMEAAPE----
---------------------------------------LVFEPMTSELY----------
---------------------------EG--------------------------QTALH
IAVVNQNMNLVRALLARRASVSA-RATGTAFRRSPCN-LIYF-GEHPLSFAACVNSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDRH-GDHLQPLDL------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HTQW------TYGPLTSTL-----YDLTEIDSSGD-----------------------
----------EQSLLELIIT-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLY------IICFTMCCIYRP
----LKPR-TN---NRT------SPR-DNTLLQQKLLQEAYMTPK-DDIRLVGELVTVIG
AIIILLVEVPDIFRMGVT--RFFGQTILGGPFHVL------------IITYAFMVLVTMV
MRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTED------------
----PEE------------------LGHFYD------YPMALFSTFELFLTIIDGP----
---ANYNVDLPFMYSITYAAFAIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQIVAT
TVMLERKL--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DRWFL-----RVEDRQDLNRQRIQRYAQAFHTRG----------
------------------SE--D--------------LDKDSVEK---------------
------------------------------------LELGCPFSPHL--SLPMP------
------SVSRS---------TSRSSAN---WE-----------------RLRQGTLRRDL
RGIINRGL----------E--DGESWE--YQI-------------------
>PANTR16225_HOG_0033281_3b_Pantroglodytes
-------MGLSL--------------------PKEKGLI-LCLWSKFCRWF-------QR
RES-WAQS-----------------------------------------------RD---
-----------EQNLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LLAAKENDVQALNKLLKY---------------------------------EDCK
VHQR------------------GA--MGETALHIAALY---DNLEAAMVLMEAAPE----
---------------------------------------LVFEPMTSELY----------
---------------------------EG--------------------------QTALH
IAVVNQNVNLVRALLARRASVSA-RATGTAFRRSPHN-LIYF-GEHPLSFAACVNSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDRH-GDHLQPLDL------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HTQW------TYGPLTSTL-----YDLTEIDSSGD-----------------------
----------EQSLLELIIT-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLY------IICFTMCCIYRP
----LKPR-TN---NRT------SPR-DNTLLQQKLLQEAYVTPK-DDIRLVGELVTVIG
AIIILLVEVPDIFRMGVT--RFFGQTILGGPFHVL------------IITYAFMVLVTMV
MRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTED------------
----PEE------------------LGHFYD------YPMALFSTFELFLTIIDGP----
---ANYNVDLPFMYSITYAAFAIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQIVAT
TVMLERKL--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DRWFL-----RVEDRQDLNRQRIQRYAQAFHTRG----------
------------------SE--D--------------LDKDSVEK---------------
------------------------------------LELGCPFSPHL--SLPTP------
------SVSRS---------TSRSSAN---WE-----------------RLRQGTLRRDL
RGIINKGL----------E--DGESWE--YQI-------------------
>GORGO19087_HOG_0033281_3b_Gorillagorillagorilla
-------MGLSL--------------------PKEKGLI-LCLWSKFCRWF-------QR
RES-WAQS-----------------------------------------------RD---
-----------EQNLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LLAAKENDVQALNKLLKY---------------------------------EDCK
VHQR------------------GA--MGETALHIAALY---DNLEAAMVLMEAAPE----
---------------------------------------LVFEPMTSELY----------
---------------------------EG--------------------------QTALH
IAVVNQNVNLVRALLARRASVSA-RATGTAFRRSPRN-LIYF-GEHPLSFAACVNSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDRH-GDHLQPLDL------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HTQW------TYGPLTSTL-----YDLTEIDSSGD-----------------------
----------EQSLLELIIT-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVSLKWKRYGRPYFCTLGAIYLLY------IICFTMCCIYRP
----LKPR-TN---NRT------SPR-DNTLLQQKLLQEAYVTPK-DDIRLVGELVTVIG
AIIILLVEVPDIFRMGVT--RFFGQTILGGPFHVL------------IITYAFMVLVTMV
MRLSSASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTED------------
----PEE------------------LGHFYD------YPMALFSTFELFLTIIDGP----
---ANYNVDLPFMYSITYAAFAIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQIVAT
TVMLERKL--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DRWFL-----RVEDRQDLNRQRIQRYAQAFHTRG----------
------------------SE--D--------------LDKDSVEK---------------
------------------------------------LELGCPFSPHL--SLPTP------
------SVSRS---------TSRSSAN---WE-----------------RLRQGTLRRDL
RGIINRGL----------E--DGESWE--YQI-------------------
>CHLSB10111_HOG_0033281_3b_Chlorocebussabaeus
-------MGLSL--------------------PKEKGLI-LCLWSKFCRWF-------QR
RES-WAQS-----------------------------------------------RD---
-----------EQNLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LLAAKENDVQALNKLLKY---------------------------------EDCE
VHQR------------------GA--MGETALHIAALY---DNLEAAMVLMEAAPE----
---------------------------------------LVFEPMTSELY----------
---------------------------EG--------------------------QTALH
IAVVNQNVNLVRALLARRASVSA-RATGTAFRRSPHN-LIYF-GEHPLSFAACVNSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDRH-GDHLQPLDL------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HTQW------TYGPLTSTL-----YDLTEIDSSGD-----------------------
----------EQSLLELIIT-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLY------IICFTICCIYRP
----LKPR-TN---NRT------NPR-DNTLLQQKLLQEAYVTPK-DDIRLVGELVTVIG
AIIILLVEIPDIFRMGVT--RFFGQTILGGPFHVL------------IITYAFMVLVTMV
MRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTED------------
----PEE------------------LGHFYD------YPMALFSTFELFLTIIDGP----
---ANYNVDLPFMYSITYAAFAIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQIVAT
TVMLERKL--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DRWFL-----RVEDRQDLNRQRIQRYAQAFHTRG----------
------------------SE--D--------------LDKDSVEK---------------
------------------------------------LELGCPFSPHL--SLPTP------
------SVSRS---------TSRSSAN---WE-----------------RLRQGTLRRDL
RGIINRGL----------E--DGEGWE--YQI-------------------
>NOMLE10826_HOG_0033281_3b_Nomascusleucogenys
-------MGLPL--------------------PKEKGLI-LRLWSKFCRWF-------QR
QES-WAQS-----------------------------------------------RD---
-----------EQNLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LLAAKENDVQALNKLLKY---------------------------------EDCK
VHQR------------------GA--MGETALHIAALY---DNLEAAMVLMEAAPE----
---------------------------------------LVFEPMTSELY----------
---------------------------EG--------------------------QTALH
IAVVNQNVNLVRALLARRASVSA-RATGTAFRRSPHN-LIYF-GEHPLSFAACVNSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDRH-GDHLQPLDL------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HTQW------TYGPLTSTL-----YDLTEIDSSGD-----------------------
----------EQSLLELIIT-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLY------IICFTMCCIYRP
----LKPR-TN---NRT------SPR-DNTLLQQKLLQEAYVTPK-DDIRLVGELVTVIG
AIIILLVEIPDIFRMGVT--RFFGQTILGGPFHVL------------IITYAFMVLVTMV
MRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTED------------
----PEE------------------LGHFYD------YPMALFSTFELFLTIIDGP----
---ANYNVDLPFMYSITYAAFAIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQIVAT
TVMLERKL--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DRWFL-----RVEDRQDLNRQRIQRYAQAFHTRG----------
------------------SE--D--------------LDKDSVEK---------------
------------------------------------LELGCPFSPHL--ALPTP------
------SVSRS---------TSRSSAN---WE-----------------RLRQGTLRRDL
RGIINRGL----------E--DGESWE--YQI-------------------
>PAPAN12762_HOG_0033281_3b_Papioanubis
-------MGLSL--------------------PKEKGLI-LCLWSKFCRWF-------QR
RES-WAQS-----------------------------------------------RD---
-----------EQNLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LLAAKKNDVQALNKLLKY---------------------------------EDCE
VHQR------------------DARSHGETALHIAALY---DNLEAAMVLMEAAPE----
---------------------------------------LVFEPMTSELY----------
---------------------------EG--------------------------QTALH
IAVVNQNVNLVRALLARRASVSA-RATGTAFRRSPHN-LIYF-GEHPLSFAACVNSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDRH-GDHLQPLDL------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HTQW------TYGPLTSTL-----YDLTEIDSSGD-----------------------
----------EQSLLELIIT-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLY------IICFTICCIYRP
----LKPR-TN---NRT------SPR-DNTLLQQKLLQEAYVTPK-DDIRLVGELVTVIG
AIIILLVEIPDIFRMGVT--RFFGQTILGGPFHVL------------IITYAFMVLVTMV
MRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTED------------
----PEE------------------LGHFYD------YPMALFSTFELFLTIIDGP----
---ANYNVDLPFMYSITYAAFAIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQIVAT
TVMLERKL--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DRWFL-----RVEDRQDLNRQRIQRYAQAFHTRG----------
------------------SE--D--------------LDKDSVEK---------------
------------------------------------LELGCPFSPHL--SLPTP------
------SVSRS---------TSRSSAN---WE-----------------RLRQGTLRRDL
RGIINRGL----------E--DGEGWE--YQI-------------------
>PONAB14818_HOG_0033281_3b_Pongoabelii
-------MGGFL--------------------PKAEGPG-SQLQKLLPSFL-------VR
EQD-WDQH-----------------------------------------------LD---
-----------KLHMLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LLAAKENDVQALNKLLKY---------------------------------EDCK
VHQR------------------GA--MGETALHIAALY---DNLEAAMVLMEAAPE----
---------------------------------------LVFEPMTSELY----------
---------------------------EG--------------------------QTALH
IAVVNQNVNLVRALLACRASVSA-RATGTAFRRSPHN-LIYF-GEHPLSFAACVNSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDRH-GDHLQPLDL------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HTQW------TYGPLTSTL-----YDLTEIDSSGD-----------------------
----------EQSLLELIIT-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLY------IICFTMCCIYRP
----LKPR-TN---NRT------SPR-DNTLLQQKLLQEAYVTPK-DDIRLVGELVTVIG
AIIILLVEIPDIFRMGIT--RFFGQTILGGPFHVL------------IITYAFMVLVTMV
MRLISASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTED------------
----PEE------------------LGHFYD------YPMALFSTFELFLTIIDGP----
---ANYNVDLPFMYSITYAAFAIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQIVAT
TVMLERKL--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DRWFL-----RVEDRQDLNRQRIQRYAQAFHTRG----------
------------------SE--D--------------LDKDSVEK---------------
------------------------------------LELGCPFSPHL--SLPTP------
------SLSRN---------TSRSSAN---WE-----------------RLRQGTLRRDL
RGIINRGL----------E--DGESWE--YQI-------------------
>CALJA20669_HOG_0033281_3b_Callithrixjacchus
-------------------------------------------------FL-------VR
EED-WDQH-----------------------------------------------LD---
-----------KLHMLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LLAAKENDVRALSKLLKY---------------------------------EDCE
VHQR------------------GA--MGETALHIAALY---DNLEAAMVLMEAAPE----
---------------------------------------LVFEPMTSELY----------
---------------------------EG--------------------------QTALH
IAVVNQNVNLVRALLAHRASVSA-RATGTAFRRSPHN-LIYF-GEHPLSFAACVNSEEIV
RLLIE---HGADVRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDRH-GDHLQPLDL------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HTQW------TYGPLTSTL-----YDLTEIDSSGD-----------------------
----------EQSLLELIIT-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVSLKWKRYGRPYFCVLGAIYLLY------IICFTMCCVNRP
----LKPR-TN---NRT------SSR-DNTLLQQKLFQEAYVTPK-DDIRLVGELVTVIG
AVIILLVEIPDIFRMGVT--RFFGQTILGGPFHVL------------IIAYAFMVLVTMV
MRLTSANGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTED------------
----PEE------------------LGHFYD------YPMALFSTFELFLTIIDGP----
---ANYNVDLPFMYSITYAAFAIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQIVAT
TVMLERKL--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DRWFL-----RVEDRQDLNRQRIQRYAQAFHTRG----------
------------------SE--D--------------LDKDSVEK---------------
------------------------------------LELGCPFSPHL--PLPTP------
------SVSRS---------TSRSSAN---WE-----------------RLRQGTLRRDL
RGIINRGL----------E--DGEGWE--YQI-------------------
>CANFA04443_HOG_0033281_4b_Canisfamiliaris
-------MGLPL--------------------PKEKGLI-LCLWRKFCRWF-------QR
QES-WAQS-----------------------------------------------RD---
-----------EQNLQQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LLAAKENNVQALSKLLKY---------------------------------QACE
VHEK------------------GG--MGETALHIAALY---DNLEAAMVLMEAAPE----
---------------------------------------LVFEPMTSELY----------
---------------------------EG--------------------------QTALH
IAIVNQNVNLVRALLARGASVSA-RATGTAFRRSPRN-LIYF-GEHPLSFAACVGSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDGR-RDHLQSLDL------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HIQW------TYGPLTSTL-----YDLTEIDSSGD-----------------------
----------EQSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVSLKWKRYGRPYFCVLGALYLLY------IICFTMCCVYRP
----LKPR-TN---NHT------GPR-DNTLLQQKLLQEAYVTPE-DDIRLVGELVTVIG
AVIILLAEIPDIFRVGVT--RFFGQTILGGPFHVL------------IITYACMVLVTMV
MRLTNTNGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTED------------
----PDE------------------LGHFYD------YPMALFSTFELFLTVIDGP----
---ANYDVDLPFMYSITYAAFAIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DRWFL-----RVEDRQDLNRQRARRYAQAFHGQG----------
------------------AD--D--------------LDKAS-EK---------------
------------------------------------GQLGHPLGLHL--ALPTP------
------SVSRS---------TSRSSTN---WE-----------------RLRQGTLRREV
RGLANRAL----------E--DCEGWE--YQI-------------------
>MUSPF00879_HOG_0033281_4b_Mustelaputoriusfuro
-------MGLPL--------------------PKEKGLI-LCLWRKFCRWF-------QR
QES-WAQS-----------------------------------------------RD---
-----------EQNLQQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LLAAKENNVQALHKLLKY---------------------------------EACD
MHQR------------------GA--MGETALHIAALY---DNLEAAIVLMEAAPE----
---------------------------------------LVFEPMTSKLY----------
---------------------------EG--------------------------QTALH
IAIVNQNVNLVRTLLAHGASVSA-RATGTAFRRSPRN-LIYF-GEHPLSFAACVGSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDGH-RDHLQSLDL------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HIQW------TYGPLTSTL-----YDLTEIDSSGD-----------------------
----------EQSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVSLKWKRYGRPYFCVLGAIYLIY------IICFTMCCVYRP
----LKPR-TN---NHT------GPR-DNTLLQQKLLQEAYVTPE-DDIRLVGELVTVIG
AVIILLAEIPDIFRVGVT--RFFGQTILGGPFHVL------------IIAYACMVLVTMV
MRLMNASGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTED------------
----PDE------------------LGHFYD------YPMALFSTFELFLTVIDGP----
---ANYDVDLPFMYSITYAAFAIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DRWFL-----RVEDRQDLNRQRVRRYVQAFHTQG----------
------------------SD--D--------------LDKGS-EK---------------
------------------------------------LQLGHPFGPHL--SLSTP------
------SVSRS---------TSRSSTN---WE-----------------RLRQGTLRREL
RGLTNRAL----------E--DGDGWE--YQI-------------------
>AILME07707_HOG_0033281_4b_Ailuropodamelanoleuca
-------MGLPL--------------------PKEKGLI-LCLWRKFCRWF-------QR
QEP-WAQS-----------------------------------------------RD---
-----------EQNLQQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LLAAKENNVQALSKLLKY---------------------------------EACE
VHQR------------------GA--MGETALHIAALY---DNLEAAMVLMEAAPE----
---------------------------------------LVFEPMTSELY----------
---------------------------EG--------------------------QTALH
IAIVNQNVNLVRALLAHGASVSA-RATGTAFRRSPRN-LIYF-GEHPLSFAACVGSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHVLILQPNKT---------------------
--------FACQ---------MYNLLLSYDGR-GDHLQPLDL------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HIQW------TYGPLTSTL-----YDLTEIDSSGDG----------------------
---------EEQSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
----PKARQILDQTPVKELVSLKWKRYGRPYFCVLGALYLLY------IVCVTMCCVYRP
----LKPR-TN---NHT------GPR-DNRLLQQKLLQEAYVTPE-DDIRLVGELVSVIG
AVIILLAEIPDIFRVGVT--RFFGQTILGGPFHVL------------IITYACMVLVTMV
MRLTNTNGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFASGGAAFYIIFQTED------------
----PDE------------------LGHFYD------YSMALFSTFELFLTVIDGP----
---ANYDVDLPFMYSITYAAFAIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DCWFL-----RVEDRQDLNRQRVQRYAQAFHSQG----------
------------------SE--D--------------VDKAS-EK---------------
------------------------------------LQLGSPLGPHL--SLPTP------
------SVSRS---------TSRSSTN---WE-----------------RLRQGTLRRDL
RGLTNRAL----------E--DGEGWE--YQI-------------------
>Tarsier_TRPV6
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
IWES-----------------------------------------P----------L---
-----LLAAKENNVQTLNKLLKY---------------------------------ETCE
VHQR------------------GA--MGETALHVAALY---DNLEVAMVLMEAAPE----
---------------------------------------LVFEPMTSELY----------
---------------------------EG--------------------------QTALH
IAVVNQNVNLVRALLARGASVSA-RATGTAFRRSSHN-LIYF-GEHPLSFAACVSSEEIE
RLLIG---HGADVRAHDSLGNT-----VLHILTLQPNKT---------------------
--------FACQ---------MYNLLLSYDGC-RDHLQPLDL------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HIQW------AYGPLSSTL-----YDLTEIDSSGD-----------------------
----------EQSLLELIIT-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVSLKWKRYGRPYFCVLGAIYLLY------IICFTMCCIYRP
----LKPR-TS---NHT------NPR-DNTLLQQKLLHXXXXXXX-XXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXX------------XXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXNVMYLRR--QMLS-FTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTED------------
----PGK------------------LGHFYD------YPMALFSTFELFLTIIDGP----
---ANYDVDLPFMYCITYAAFGIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DRWFL---------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------
>OTOGA10500_HOG_0033281_3b_Otolemurgarnettii
-------MGLSL--------------------PKEKGLI-LCLWSKFCRWF-------QR
QES-WAQS-----------------------------------------------RD---
-----------EQNLLQ----------------------------------QKR------
IWES-----------------------------------------P----------F---
-----LLAAKENDVQALHKMLKY---------------------------------NACE
VHQRE---------------MIGA--MGETALHVAALY---DNVEAAIVLIEAAPE----
---------------------------------------LVFEPMTSELY----------
---------------------------EG--------------------------QTALH
IAVVNQNVNLVRALLNHGASVSA-RATGTAFRRSPRN-LIYF-GEHPLSFAACVGSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILVLQPNKT---------------------
--------FACQ---------MYNLLLSYDGR-GDHLQPLDT------------------
------VPNHQGLTPFKLSGVEGNTV-----------MFQHLMQK--------------R
K-HIQW------TYGPLTSTL-----YDLTEIDSSGC-----------------------
----------EQSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVSLKWRRYGRPYLCVLGAIYLLY------IICFTMCCVYRP
----LKSR-TT---NRT------STR-DNTLLQQKLLQEAYVTPM-DDIRLVGELVTILG
ALIILLIEIPDIFKMGVT--RFFGQTILGGPFHVL------------IITYALLVLVTMV
MRITNTNGEVVPMSLALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYVIFQTED------------
----PTE------------------LGHFYD------YPMALYSTFELFLTIIDGP----
---ANYSVDLPFMYSITYAAFAIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DRWFL-----RVEDRQDLNRQRIQRYAKAFHTLG----------
------------------SE--D--------------SDKDSVDK---------------
------------------------------------LDLGRPSSPHL--SLSIP------
------SVSRS---------TSRSSIN---WE-----------------RLRQGTLRKDL
RGLVNRGL----------E--DGDSWE--YQI-------------------
>MOUSE18362_HOG_0033281_3b_Musmusculus
-------MGWSL--------------------PKEKGLI-LCLWNKFCRWF-------HR
QES-WAQS-----------------------------------------------RD---
-----------EQNLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LLAAKENDVQALSKLLKF---------------------------------EGCE
VHQR------------------GA--MGETALHIAALY---DNLEAAMVLMEAAPE----
---------------------------------------LVFEPMTSELY----------
---------------------------EG--------------------------QTALH
IAVINQNVNLVRALLARGASVSA-RATGSVFHYRPHN-LIYY-GEHPLSFAACVGSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDG--GDHLKSLEL------------------
------VPNNQGLTPFKLAGVEGNIV-----------MFQHLMQK--------------R
K-HIQW------TYGPLTSTL-----YDLTEIDSSGD-----------------------
----------DQSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVSLKWKRYGRPYFCVLGAIYVLY------IICFTMCCVYRP
----LKPR-IT---NRT------NPR-DNTLMQQKLLQEAYVTPK-DDLRLVGELVSIVG
AVIILLVEIPDIFRLGVT--RFFGQTILGGPFHVI------------IITYAFMVLVTMV
MRLTNVDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTED------------
----PDE------------------LGHFYD------YPMALFSTFELFLTIIDGP----
---ANYDVDLPFMYSVTYAAFAIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DRWFL-----RVEDRQDLNRQRIRRYAQAFQQQDGL--------
-----------------YSE--D--------------LEKDSGEK---------------
------------------------------------LETARPFGAYL--SFPTP------
------SVSRS---------TSRSSTN---WE-----------------RLRQGALRKDL
RGIINRGL----------E--DGEGWE--YQI-------------------
>RATNO14979_HOG_0033281_3b_Rattusnorvegicus
-------MGWSL--------------------PKEKGLI-LCLWNKFCRWF-------HR
RES-WAQS-----------------------------------------------RD---
-----------EQNLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LLAAKENNVQALIKLLKF---------------------------------EGCE
VHQK------------------GA--MGETALHIAALY---DNLEAAMVLMEAAPE----
---------------------------------------LVFEPMTSELY----------
---------------------------EG--------------------------QTALH
IAVINQNVNLVRALLARGASVSA-RATGSVFHYRPHN-LIYY-GEHPLSFAACVGSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDG--GDHLKSLEL------------------
------VPNNQGLTPFKLAGVEGNIV-----------MFQHLMQK--------------R
K-HIQW------TYGPLTSTL-----YDLTEIDSSGD-----------------------
----------DQSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVSLKWKRYGRPYFCVLGAIYVLY------IICFTMCCVYRP
----LKPR-IT---NRT------NPR-DNTLLQQKLLQEAYVTPK-DDLRLVGELVSIVG
AVIILLVEIPDIFRLGVT--RFFGQTILGGPFHVI------------IVTYAFMVLVTMV
MRLTNSDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTED------------
----PDE------------------LGHFYD------YPMALFSTFELFLTIIDGP----
---ANYDVDLPFMYSITYAAFAIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DRWFL-----RVEDRQDLNRQRIRRYAQAFQQQDDL--------
-----------------YSE--D--------------LEKDSGEK---------------
------------------------------------LEMARPFGAYL--SFPTP------
------SVSRS---------TSRSSTN---WE-----------------RLRQGALRKDL
QGIINRGL----------E--DGEGWE--YQI-------------------
>DIPOR12044_HOG_0033281_3b_Dipodomysordii
-------MGWSL--------------------PKEKGLI-LCLWNKLCKWS-------HR
QES-WTQS-----------------------------------------------RD---
-----------EQNLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LLAAKENDVQTLSKLLKY---------------------------------QGCD
VHQR------------------GA--MGETALHIAALY---DNL-AAMLLMEAAPE----
---------------------------------------LVFEPMQ--------------
---------------------------EG--------------------------QTALH
IAVMNQNVNLVRALLARGASVSA-RATGFAFHLSPHN-LIYY-GEHPLSFAACVGSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDG--GDHLQSLEL------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HIQW------TYGPLTSTL-----YDLTEIDSSGD-----------------------
----------EQSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVSFKWKRYGRPYFCVLGAIYLVY------IICFTMCCVYRP
----LKPR-TT---NRT------NPR-DNTLLQQKLLQEAYVTPK-DDLRLVGELVTIIG
AVIILLVEIPDIFRLGVT--RFFGQTILGGPFHVI------------IITYAFTVLVTMV
MRLTNTDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTED------------
----PDE------------------LGHFYD------YPMALFSTFELFLTIIDGP----
---ANYDVDLPFMYSITYAAFAIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGRDYGLG--------------
----------------DRWFL-----RVEDRQDLNRQRILRYAQAFQPQDAL--------
-----------------CSE--D--------------LDKDSGEK---------------
------------------------------------LELGRPFGPYL--SFPTP------
------SVSRS---------TSRSSTN---WE-----------------RLRQGTLRRDL
RGIINRGV----------E--DGEGWE--YQV-------------------
>SPETR02470_HOG_0033281_3b_Spermophilustridecemlineatus
-------MGLSL--------------------PKEKGLI-LCLWNKFCRWF-------HR
QES-SAQS-----------------------------------------------RD---
-----------EQNLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LLAAKENDVQVLSKLLKY---------------------------------EACE
VHQRE---------------MPGA--MGETALHIAALY---DNLEAAMVLMEAAPE----
---------------------------------------LVFEPMTSELY----------
---------------------------EG--------------------------QTALH
IAVMNQNVNLVRALLSHGASVSA-RATGTAFQRSPHN-LIYY-GEHPLSFAACVGSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDG--GDHLQPLEL------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HIQW------TYGPLTSTL-----YDLTEIDSSGD-----------------------
----------EQSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------ARHILDQTPVKELVSLKWKRYGRPYFCVLGAIYLLY------IICFTMCCVYRP
----LKPR-TT---NRT------NPR-DNTLLQQKLFQEAYVTPK-DDLRLVGELVTVIG
AVIILLVEIPDIFRFGVT--RFFGQTILGGPFHVI------------IVTYAFMVLVTMV
MRLTNADGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMVVVILGFAS---AFYIIFQTED------------
----PDE------------------LGHFYD------YPMALFSTFELFLTIIDGP----
---ANYDVDLPFMYSITYAAFAIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGSEYGLG--------------
----------------DRWFL-----RVEDRQDLNRQRIRRYAQAFQPQEVL--------
-----------------CSE--G--------------LDKDSGGK---------------
------------------------------------PERCRPLGPHL--SFPTP------
------SVSRS---------TSRSSIN---WE-----------------RLRQGTLRRDL
RGMINQGL----------E--DGEGWE--YQI-------------------
>MICMU10181_HOG_0033281_3b_Microcebusmurinus
-------MGLPL--------------------PKEKGLI-LCLWSKFCRWF-------QR
RES-WVQS----------------------------------------------PRM---
-----------KQNLLQ----------------------------------RKR------
IWES-----------------------------------------P----------F---
-----LLAAKENDVQALNKLLKY---------------------------------KACE
VHQR------------------GA--MGETALHVAALY---DNLEAAILLMEAAPE----
---------------------------------------LVFEPMTSELY----------
---------------------------EG--------------------------QTALH
IAIVNQNMNLVRALLAHGASVSA-RATGAAFRRSPQN-LIYF-GEHPLSFAACVGSEEIV
RLLIE---HGANIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDGR-GDHLQPLEA------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HIQW------TYGPLTSTL-----YDLTEIDSSGD-----------------------
----------DQSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVSLKWRRYGRPYFCVLGAVYLLY------IICFTVCCVYRP
----LKPR-TT---NRT------SPR-DNTLLQQKLLQEAYVTSS-DDMRLVGELVTVIG
ALIILLVEIPDILRMGAT--RFFGQTILGGPFHVL------------IITYAFMVLVTMV
MRLTNTDGEVVPMSLALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYVIFQTQD------------
----PEE------------------LGHFYD------YPMALFSTFELFLTIIDGP----
---ANYSVDLPTMYSVTYSAFAIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DRWFL-----RVEDRQDVSRQRLLRYAQAFHNPD----------
------------------SE--D--------------LDKGSVEK---------------
------------------------------------RELGRPSSPHL--SLPTP------
------SVSRS---------TSRSSAN---WE-----------------RLRQGTLRREL
RGLMGRGL----------E--DWDGWE--YQI-------------------
>RABIT_TRPV6
M-----HSGAKP--------------------PP---LL-LLM-----------------
------------------------------------------------------------
-------------SLLTIA-AFPIP-------------------------FSVR------
IWES-----------------------------------------P----------L---
-----LLAAKENNVQALNKLLKY---------------------------------DSCE
VHQR------------------GA--LGETALHIAALY---DNLEAAMVLMEAAPD----
---------------------------------------LVFEPMTSELY----------
---------------------------EG--------------------------QTALH
IAVMNQNLNLVRALLARGASVSA-RATGAAFRRSPHN-LIYY-GEHPLSFAACVGSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILILQSNKT---------------------
--------FACQ---------MYNLLLSYDGH-SDHLQSLEL------------------
------MPNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-YIQW------TYGPLTSTL-----YDLTEIDSSGD-----------------------
----------EQSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------ARHILDQTPVKELVSLKWKRYGRPYFCVLGAIYLLY------IICFTMCCIYRP
----LKLR-TS---NRT------DPR-DNTLLQQKLLQEAYVTSR-DDIRLVGELVTVIG
AMIILLVEIPDIFRLGVT--RFFGHTILGGPFHVL------------IITYAFMVLMTMV
MRLTNTDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTQD------------
----PDE------------------LGHFYS------YPMALFSTFELFLTIIDGP----
---ANYAVDLPFMYCITYAAFGIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGRKYGLG--------------
----------------DRWFL-----RVEDRQDLNRHRMRRYAQAFNSLG----------
------------------SD--D--------------LDKDSEEK---------------
------------------------------------LELRHPLGPRQ--PFPMP------
------ALSRS---------ASRSSMN---WE-----------------KLRQGALRRDL
RGVINRAL----------E--DEEGWE--YQI-------------------
>TUPBE07630_HOG_0033281_3b_Tupaiabelangeri
-------MGLSL--------------------PKEKALI-LCLWSKFCR-F-------QR
RKS-WAQS-----------------------------------------------RD---
-----------ELNLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LLAAKENDIQALNKLLKY---------------------------------EAFE
VHQR------------------GA--LGETALHVAALY---DNLEAAMLLMEAAPE----
---------------------------------------LVFEPMTSELY----------
---------------------------EG--------------------------QTALH
IAVVNQNVNLVRALLAHGASVSA-RATGTAFHRSPHN-LIYF-GEHPLSFAACVGSEEIV
RLLIE---HGADIRARDSLG-------VLHIFVF--SKT---------------------
--------FACK---------MYNLLLSYDH--EDHLQPLDL------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HTQW------TYGPLTSTL-----YDLTEIDSSGD-----------------------
----------EQSLLELIIT-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVSLKWKRYGRPYFCVLGAIYLLY------IICFTTCCVYRP
----LKPR-TS---NRT------SLR-DNTLLQQKLLQEAYETPK-DDIRLVGELVSIIG
AVIILLVEIPDIFRVGVT--RFFGQTILGGPFHVL------------IITYAFMVLVTMV
MRLTNADGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTED------------
----PEE------------------LGHFYD------YPMALFSTFELFLTIIDGP----
---ANYNVDLPFMYSITYAAFAIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQPGAP
T------------------------------FPS-LSLCGTLSSL---------------
---------------------------VEDRQDLNRQRIRRYAQAFHNPG----------
------------------TE--G--------------LDKDSGEK---------------
------------------------------------LELGRPFGPQL--SLPTP------
------SVSRS---------TSRSSTN---WE-----------------RLRQGTLRRDL
RGVLNQGL----------E--DGEGWE--YQI-------------------
>CAVPO13925_HOG_0033281_3b_Caviaporcellus
-------MGLSL--------------------SKEKGLI-LRLWNKFCRLF-------HR
QDS-WTQS-----------------------------------------------RD---
-----------ELNLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LLAAKENDVQALSKLLKY---------------------------------EACD
VHQKV---------------MPGA--MGETALHIAALY---DNLEVAMVLIEAAPD----
---------------------------------------LVFEPMTCELY----------
---------------------------QG--------------------------QTALH
IAVMNRNVNLVRALLIRGASVSA-RATGLAFQHSPDN-LIYY-GEHPLSFAACVGSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDG--GDHLQSLEL------------------
------VPNYQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HVQW------TYGPLTSTL-----YDLTEIDSSED-----------------------
----------EQSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------AQQILDLTPVKELVSLKWKRFGRPYFCVLGAIYLLY------IICFTVCCVYRP
----LKPR-TT---NET------GPR-DNRLLEQKLLQEAYTTPE-DDLRMVGELVSVFG
AVVILLVEIPDILRLGAT--RFFGHTILGGPFHVI------------IITYACMVLVTMV
MRLTNTDGEVVPMSLALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTED------------
----PDE------------------LGHFFD------YSMALFSTFELFLTVIDGP----
---ANYDVDLPFMYSITYAAFAIIATLLMLNLLIAM-MGDTHWRVSHEQDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DRWFL-----RVEDRQDLNLKRIQRYAKAFQPEGIH--------
-----------------DSE--D--------------QDKDPGEK---------------
------------------------------------LEMRYPTDPYL--SFPTP------
------SVSRS---------TSRSSTN---WE-----------------RLRQGTLRSDL
RGMINRGL----------E--DGEGWE--YQI-------------------
>OCHPR04786_HOG_0033281_3b_Ochotonaprinceps
-------MGLSL--------------------PKEKGLI-LSLQRKLCRWF-------QR
QES-WVQS-----------------------------------------------RD---
-----------EQNLLQ----------------------------------QK-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------XEHPLSFAACVGNEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDEH-RDHLQSLEF------------------
------VPNLEGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HIQW------TYGPLTSTL-----YDLTEIDSSGD-----------------------
----------EHSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLY------IICFTMCCIYRP
----LKPR-TS---NRT------NPR-DNTLLQQKLLQEAYLTPA-DDVRMAGELVTILG
AVIILLVEIPDIFRLGVT--RFFGHTILGGPFHVL------------IITYAFMVLMTMV
MRLTNTDGEVVPMSFALVLGWCNVMYFARGFQMLG-FTIMIQT-----------------
-------------MIFGDLMRFCWLMAVVIFGFAS---AFYIIFQTED------------
----PDE------------------LGHFYS------YLMALFSTFELFLTVIDGP----
---ANYDVDLPVMYCITYAAFAIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------CMWPR-SGVCGLKYGLG--------------
----------------DRWFL-----RVEDRQDLNRHRIRRYAQAFHSP-----------
------------------SD--D--------------LDKDSDEK---------------
------------------------------------MELGHSLGLHQ--SFLMP------
------SLSRS---------SSRSSTN---WE-----------------KLRQGALKRDL
QGVINRAL----------E--DEDGWE--YQI-------------------
>DASNO20674_HOG_0033281_5a_Dasypusnovemcinctus
-------MGLLL--------------------PKEKGLI-LCLWSKFCTWF-------QR
RES-WAHR-----------------------------------------------RD---
-----------ELNLLQ----------------------------------QKR------
ICEC-----------------------------------------P----------L---
-----LLAAKENNIPALTKLLKY---------------------------------EDCE
LHQR------------------GA--MGETALHIAALY---DNLEAAVLLMEAAPD----
---------------------------------------LVFEPMTSELY----------
---------------------------EG--------------------------QTALH
IAVVNQNLNLVRALLAHGASVSA-RATGVAFRRSPCN-LIYF-GEHPLSFAACVGNEEIV
QLLIE---HGADIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDGR-GDYLQSLDQ------------------
------MRNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HIQW------TYGPLTSTL-----YDLTEIDSLGD-----------------------
----------EQSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVSLKWKRYGRPYFCMLGAIYMLY------IICFTMCCVNRP
----LKLR-TS---NRT------SSR-DNTIYQQKLLQEAYVISR-DGIRLVGEMVSVIG
AVIILLVEIPDIFRVGVT--RFFGQTILGGPFHVL------------MITYACMVLVTMV
MRLTNANGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS--AAFYIIFQTED------------
----PKK------------------LGHFQN------YLMALFSTFELFLTIIDGP----
---ANYDVDLPFMYSITYAAFAIIAALLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGFCGREYGLG--------------
----------------DRWYL-----RVEDRQDLNQQRIRRYAQAFHQMG----------
------------------PS--D--------------FDKNSVEK---------------
------------------------------------LELDRHFGPHL--SLPTP------
------SVSRS---------TSRSSTN---WD-----------------RLRQGTLRRDL
WGLINRGL----------E--DEEGWE--YQI-------------------
>Sloth_TRPV6
------------------------------------------IW----------------
------------------------------------------------------------
------------------------------------------------------------
--ES-----------------------------------------P----------L---
-----LLAAKENNVQALTKLLKY---------------------------------EACK
VHQR------------------GA--MGETALHIAALY---DNLEAAMVLMEAAPE----
---------------------------------------LVFEPMTSELY----------
---------------------------EX--------------------------XXXXX
XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXX-XXXX-XXXXXXXXXXXXXXXXX
XXXXX---XXXXXXXXXXXXXX-----XXXXXXXXXXXX---------------------
--------XXXX---------XXXXXXXXXXX-XXXXXXXXX------------------
------XXXXXXXXXXXXXXXXXXXX-----------MFQHLMQK--------------R
K-HIQW------TYGPLTSTL-----YDLTEIDSSGD-----------------------
----------EQSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVSLKWRRYGRPYFCMLGAIYVLY------IMCFTMCCVYRP
----LKTR-TS---NRT------SPR-DNTIYQQKLLQEAYVTPR-DDIRLVGEMVTVIG
AVIILLVEISDIFRFGVT--RFFGQTILGGPFHVL------------IITYACMVLMTML
MRLTNASGEVVPMSFP-VLGWCNV-XXXXXXXXXXXXXXXXXX-----------------
-------------XXXXXXXXXXXXXXXXXXXXXX--XXFYIIFQTED------------
----SSE------------------LGHFYN------YPMALFSTFELFLTIIDGP----
---ANYAVDLPFMYSITYAAFAIIAALLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DRWYL-----RVEDRQDLNWQRIQRYTKAFHSLG----------
------------------PD--D--------------LDKNSAEK---------------
------------------------------------PELDR---PHL--FLPVP------
------SVSRS---------TSRSSTN---WE-----------------RLRQGTLRRDL
RGVINRGL----------E--HGEGWE--YQI-------------------
>HORSE14870_HOG_0033281_4b_Equuscaballus
-------MGLPF--------------------PKEKGLI-LCLWRKFCRWF-------QR
QES-WAQS-----------------------------------------------QD---
-----------EQYLLQ----------------------------------QKR------
IWEY-----------------------------------------P----------L---
-----LLAAKENDVKALNKLLKN---------------------------------GACE
VLQR------------------GA--MGETALHIAALS---DNLEAALVLMEAAPE----
---------------------------------------LVFEPMTSELF----------
---------------------------EG--------------------------QTALH
VAIMNQNVNLVRALLAHGASVSA-RATGTAFHRSPHN-RIYF-GEHPLSFAACVGSEEIV
RLLIE---HGADTRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDGR-GNHLQSLDL------------------
------VPNLQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HIQW------TCGPLTSTI-----YDITEIDSSGD-----------------------
----------EQSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVSLKWKRYGQPYFCMLGAIYLLY------MICFTMCCIYRP
----LKPI-TS---NCT------GAE-DIIILQQKLLQEAYLTPK-DGIRLVGELVSVVG
AVILLLAEIPDILRVGFT--CFFGQTILGGPFHVI------------TITYSCMVLVTMV
MRLTNTEGEAVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTES------------
----PKE------------------LGHFHD------YPMALFSTFELFLTVIDGP----
---ANYDVNLPFMYSLTYAAFAIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKM--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DRWFL-----RVEDKQDLNQQRLRRYAQIFHNPG----------
------------------SD--DEADKASALGKESA-LDKDA-ER---------------
------------------------------------LQLGLPFSPYL--SLATP------
------SVSRS---------TSRSSTN---WE-----------------RLRQGTLGREV
KGVLNRGL----------E--DGEGWE--YQI-------------------
>FELCA02737_HOG_0033281_4b_Feliscatus
-------MGLPL--------------------PKDKRFI-LCLWRKFCSWF-------QR
RES-WAQS-----------------------------------------------RD---
-----------EQNLQQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LLAAKENNVQALNKLLKY---------------------------------EACE
VHQR----------------APGA--MGETALHIAALY---DNLEAAVVLMEAAPE----
---------------------------------------LVFEPMTSELY----------
---------------------------EG--------------------------QTALH
IAIVNQNVNLVRALLAHGASVSA-RAIGTAFCRSPRN-LIYF-GEHPLSFAACVGSEEMV
RLLIE---HGADIRAQDSLGNT-----VLHILVLQPNKT---------------------
--------FACQ---------T-----------ARRVGPLPPYS--------------VA
KCSALGTPGREALNPYRVCGKERQPE-----------MFQHLMQK--------------R
K-HIQW------TYGPLTSTL-----YDLTEIDSSGD-----------------------
----------EQSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVSLKWKKYGRPYFCVLGTIYLLY------IICFTVCCVYRP
----LKPR-TN---NHT------GPR-DNTLLQQKLLQEAYVSPQ-DDLRLVGELVTVIG
AVLILLAEIPDIFRVGVT--RFFGQTILGGPFHVL------------IITYACMVLVTMV
MRLTNANGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTED------------
----PDE------------------LGHFYD------YPMALFSTFELFLTVIDGP----
---ANYDVDLPFMYSITYAAFAIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DRWFL-----RVEDRQDLNRQRMRRYAHAFHIPA----------
------------------SE--D--------------SDKAS-EK---------------
------------------------------------LRLDHPSGPHL--CPSTP------
------SVSRS---------TSRSSAN---WE-----------------RLRQGTLRREL
RGLVNRGL----------E--DGEGWE--YQI-------------------
>ELEPHANT_TRPV6_XM_003423723
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------MFQHLMQR--------------R
K-HIQW------TYGPLTSTL-----YDLTEIDSWGE-----------------------
----------EQSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDLTPVKELVSLKWRRYGRPYFYLLGAIYLLY------IICFTMCCVYRP
----LKPR-TS---NRT------SPR-DNGLLQQKLLQEAYVTPK-DSVRLMGELVTILG
ALIILLLEIPDIFRVGVT--RFFGHTSLGGPFHIL------------IVTYACMVLVIVV
MRLTNTNGEVIPMSFALVLGWCNVMYFARGFQMIGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIVFQTED------------
----PHE------------------LGHFYN------YPMALFSTFELFLTVIDGP----
---ANYDVDLPFMFCITYAAFAIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQVVDT
TVMLERKL--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DHWYL-----RVEDRQDLNRQRVQRYAQAFQNLD----------
------------------ND--N--------------LDGNSVQK---------------
------------------------------------LRLGQTFGQHL--PVPTP------
------SVSRS---------TSRSSTN---WE-----------------RLRQGALRREL
RGVVNKGL----------EV-DQDSWE--YQI-------------------
>BOVIN15323_HOG_0033281_4b_Bostaurus
-------MGLPL--------------------PKEKGHI-LCLWRKLCRWF-------QR
QEP-WAQR-----------------------------------------------RD---
-----------EQNLLQ----------------------------------QRR------
IWES-----------------------------------------P----------L---
-----LLAAKENDIQALSKLLKY---------------------------------EACD
VHQK----------------VPGA--MGETALHVAALY---DNLEAATVLMEAAPE----
---------------------------------------LVKEPMTSELY----------
---------------------------EG--------------------------QTALH
IAVMNRNVNLVKALLAHGASVSA-RAIGSAFRLTPHN-LIYF-GEHPLSFAACMGSEEIV
RLLIK---HGADIRAQDSLGNT-----VLHILVLQPNKT---------------------
--------FACQ---------MYNLLLSYDRR-GDHLQSLDL------------------
------MLNHQGLTPFKLAGVEGNTV-----------MFQNLVQK--------------Q
K-YIQW------TCGPLTSTL-----YDLTEIDSSGE-----------------------
----------ELSLLELIVT-SKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVTLKWKRYGRPYFCVLAAMYLLY------IVCFTMCCVYRP
----LKPR-TD---NET------DPR-DNTIWEQKPLQEAYVTHQ-DHLRLVGELVSIFG
AVIILFIEITDIFRVGLS--RVFGQTILGGPFHVL------------FITYSCMVLVTMV
MRLTNTSGEVVPMSFALVLGWCSVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFFIIFQTED------------
----PNE------------------LGHFYS------YPMALFSTFELFLTIIDGP----
---ANYDVDLPFMYSITYAAFAIIAALLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLEKKL--------PR-----------CLWPR-SGICGHKFGLG--------------
----------------DRWFL-----RVEEKQDINQQRVRRYAQAFCHPG----------
------------------SE--DD-------------TER--------------------
------------------------------------LWLGGPFGTHL--SLLTP------
------SVSRS---------TSRSSIN---WE-----------------RLRQGTLKREL
RGVVNKAL----------E--DGEGWE--YQI-------------------
>SHEEP15835_HOG_0033281_4b_Ovisaries
-------MGLPL--------------------PKEKGHI-LSLWRKLCRWF-------QR
QEP-WAQR-----------------------------------------------RD---
-----------EQNLLQ----------------------------------QKR------
ICES-----------------------------------------P----------L---
-----LLAAKENNIQALRKLLKY---------------------------------EACD
VHQK----------------VPGA--VGETALHVAALY---DNLEAAMVLMEAAPE----
---------------------------------------LVKEPMTSELY----------
---------------------------EG--------------------------QTALH
IAVMNQNVNLVKALLAHGASVSA-RATGSAFRLSPHN-LIYF-GEHPLSFAACMGSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILVLQPNKT---------------------
--------FACQ---------MYNLLLSYDRR-GDHLQSLDL------------------
------MLNHQGLTPFKLAGVEGNTV-----------IFQNLVQK--------------Q
K-YIQW------TCGPLTSTL-----YDLTEIDSSGE-----------------------
----------ELSLLELIVT-SKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVTLKWKRYGRPYFCVLAATYLLY------IVCFTVCCVYRP
----LKPR-TD---NET------DPR-DSTLYQQKPRQEAYVTRQ-DHLRLVGELVSICG
AIIILFIEITDIFRVGVS--RSFGQTILGGPFHIL------------FITYSCMVLVTMV
MRLTNTSGEVVPMSFALVLGWCSVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFFIIFQTED------------
----PNE------------------LGHFFN------YPMALFSTFELFLTIIDGP----
---ANYDVDLPFMYSITYAAFAIIAALLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLEKKL--------PR-----------CLWPR-SGICGRKFGLG--------------
----------------DRWFL-----RVEEKQDINQQRVRRYAQAFCHPG----------
------------------SE--DN-------------RER--------------------
------------------------------------LWLGSPFGARL--SLPTP------
------SVSRS---------TSGSSIN---WE-----------------RLRQGTLKREL
RGVVNKAL----------E--DEEGWE--YQI-------------------
>TURTR05381_HOG_0033281_4b_Tursiopstruncatus
-------MGLPL--------------------PREKGHI-LCLWRKFRRWF-------QR
QES-WAQR-----------------------------------------------RD---
-----------EQNLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LTAAKENDIQALVKLLKY---------------------------------EACD
VHQK------------------GA--LGETALHVAALY---DHLEAAIVLMEAAPE----
---------------------------------------LVDEPITSELY----------
---------------------------EG--------------------------QTALH
MAIMNQNVNLVKALLAHGASVSA-RAVGSAFCLSPHN-LLYF------------------
-------------------XNT-----VLHILVLQPSKT---------------------
--------FACQ---------MYNLLLSYDGH-RDHLQSLDL------------------
------VPNHQGLTPFKLAGVEGNTT-----------MFQHLMQK--------------R
K-HIQW------TCGPLTSTL-----YDLTEIDSSGE-----------------------
----------EQSLLELIVT-SKKRE----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------XEAYVTPE-DHLRLVGELVSVFG
AVIILLIEIPDIFRVGVT--RFFGQTILGGPFHVL------------FITYACMVLVTMV
MRLTNTNGEVVPMSFALVLGWCNVMYFARGFQMLGPFTVMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFFIIFQTED------------
----PNE------------------LGHFYS------YPMALFSTFELFLTIIDGP----
---ANYTVDLPFMYSVTYAAFAIIAALLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLEKKL--------PR-----------CLWPR-SGICGRKFGLG--------------
----------------DRWFL-----RVEDRQDLNRQRVRRYAQAFCNAG----------
------------------SE--DD------------------------------------
------------------------------------MEGRGLGGPHL--SLPAP------
------SVSRS---------TSRSSTN---WE-----------------RLREATR-RER
RGTMTMAL----------E--DGQCWE--YQI-------------------
>PIGXX07931_HOG_0033281_4b_Susscrofa
-------MGLPL--------------------PKEKGLI-LCLWRKLCRWF-------QR
QES-WAQS-----------------------------------------------QD---
-----------EQNLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LLAAKENDVQALTKLLKS---------------------------------EACD
VHQK------------------GA--LGETALHIAALY---DNLEAALVLMEAAPE----
---------------------------------------LVKEPVTCELC----------
---------------------------EG--------------------------QTALH
IAIMNQNMNLVKALLTHGASVSA-RVTGLKFRLSPQN-LIYF-GEYPLSFAACMGSEEMV
RLLID---HGADIRAQDSLGNT-----VLHILVLQPNKT---------------------
--------FACQ---------MYNLLLSYDGR-GDHLQSLEL------------------
------VPNHEGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HIQW------VLGPLTSTL-----YDLTEIDSSGD-----------------------
----------EQSLLELLVT-SKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVSLKWRRYGRRYFWGLAAGYLLY------IICFTVCCVYRP
----LKPW-TN---NQT------DPR-DNTLLQQKLLQEAYVTPR-DHLRLVGELVSIFG
AVIILLIEIPDIFRVGVI--RFFGQTILGGPFHVL------------FITYACMVLVTMV
MRLSNTDGEVVPMSFALVLGWCNVMYFARGFHMLGPFTVMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFFIIFQTED------------
----PNK------------------LGHFYS------YPMALFSTFELFLTIIDGP----
---ANYDVDLPFMYSVTYAAFAIIAALLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGYKFGLG--------------
----------------DRWFL-----RWEYRQDINRQRVQRYAQAFYNSD----------
------------------SD-ED--------------MEK--------------------
------------------------------------PRLGGPFKPPQ--SLHLP------
------SVSRS---------TSRSSTN---WE-----------------RLRQGTMKSEL
MGVVNRAL----------E--DGDSWE--YQI-------------------
>MONDO14721_HOG_0033281_6a_Monodelphisdomestica
-------MGVPL--------------------PKELGLL-PSLWGKICQYL-------QG
RES-WDRR-----------------------------------------------LD---
-----------ELNLLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LLAAKENDIRALTKLLKY---------------------------------DVCD
IHQR------------------GA--LGETALHVAALY---DNFEAAKLLIEVAPE----
---------------------------------------LVTEPMTSELY----------
---------------------------EG--------------------------QTALH
IAIVNQNVNLVKALLTHGASVSA-RATGIAFRRSSHN-LIYF-GEHPLSFAACVSNEEIV
QLLIE---FGADIRAQDSLGNT-----VLHILVFQPNKT---------------------
--------FACQ---------MYNALLSYDER-SGHMKSLDL------------------
------IPNHQGLTPFKLAGVEGNTV-----------IFQHLLQK--------------K
K-HVQW------TYGPLTSTL-----YDLTEIDSWGD-----------------------
----------EQSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDLTPVKELVNLKWRRFGRPYFCVLGAIYVLY------MICFTMCCAYRP
----LKLR-SS---NRT------SLR-DISLLQQKLLQESYVTRE-DNIRMVGELVSVIG
AVAILLLEIPDIFRVGIA--RYFGQTILGGPFHAI------------IVTYACMVLVTMV
MRLTSTSGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLLRFCWLMAVVILGFAS---AFYIIFQTED------------
----QDE------------------LGHFFD------YPMALFSTFELFLTIIDGP----
---ANYDVDLPFMYSITYAAFAIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DRWYL-----RVEDRQDPSRQRIYRYAQAFSTLG----------
------------------TD--D--------------LDKDSLSK---------------
------------------------------------SDLTPTCGRHRLAATPTP------
------SISRS---------TTRSSAN---WE-----------------RLRRGTLGVNL
RGEINRGL----------E--DEEGRV--YQV-------------------
>Wallaby_TRPV6
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
IWES-----------------------------------------P----------L---
-----LLAAKENDIRALTKLLKY---------------------------------EVCD
VHQR------------------GA--LGETALHVAALY---DSFEAAKLLIEVAPD----
---------------------------------------LVTEHMTSELY----------
---------------------------EG--------------------------QTALH
IAIVNQNVNLVRTLLTCGASVSA-RATGMAFQ-NPRS-LIYF-GEYPLSFAACVGNEEIL
QLLIE---FGADVRAQDSLGNT-----VLHILVYQPNKT---------------------
--------FACQ---------MYNVLLAYDER-SGHMKSLDL------------------
------IPNHQGLTPFKLAGVEGNTV-----------IFQHLLQK--------------R
K-HIQW------TYGPLTSTL-----YDLTEIDSCGD-----------------------
----------EQSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------ARQILDLTPVKELVSLKWRRFGRPYFCVLGAIYVLY------MICFTMCCVYRP
----LKPR-SS---NRT------SLR-DITFLQQKLLQXXXXXXX-XXXXXXXXXXXXXX
XXXXXXXXIPDVFRIGFT--QYFGHTILGGPFHVI------------XXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----------------
-------------XXXXXXXXXCWLMAVV-LSFAF---AFYIIFQTED------------
----PSK------------------LGQFFS------YPMSLFTTFELFLTIIDGP----
---ANYDVDLPFMYSVVYFAFAIIAVLLMLNLFIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DRWFL-----RVEDRQDPSRQRIHRYAQAFNPSG----------
------------------TD--D--------------LDKDTLSK---------------
------------------------------------LDLTPDCGHHRL-ATPTP------
------SISRN---------TTRSSAN---WE-----------------RLRRGTLGVNL
RGEINRGL----------E--EEEGMV--YQV-------------------
>PTEVA02528_HOG_0033281_4b_Pteropusvampyrus
-------VGSPL--------------------PEKNGFL-LCLWRKFCRWF-------QR
QEA-WAQS-----------------------------------------------RD---
-----------EQNLLQ----------------------------------QKR------
ILGC-----------------------------------------P----------F---
-----LLAARENDVPALGKLLKC---------------------------------QAWE
VHQR------------------GA--LGETALHVAALY---DNLEAAMVLMEAAPE----
---------------------------------------LVKEPMTSELY----------
---------------------------AG--------------------------QTALH
VAILNQNVNLVCALLSHGASVSA-RATGTAFHLSPHN-HIYF-GEHPLSFAACVGSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHVLVFQPNRT---------------------
--------FACQ---------MYNLLLSYDRR-GDHPQSLDL------------------
------VPNRQGLTPFKLAGVEGNAV-----------MFQHLMQK--------------W
K-HSQG------TFGLVTYTL-----YDLTEIDSAGD-----------------------
----------EPSLLELIVT-TKKRE----------------------------------
------------------------------------------------------------
------ARHILDQTPVKELVSLKWKRYGRPYFCLLGALYVLY------IICFTMCCVYRP
----LKPR-TD---NRT------QPR-DNTLLQQKLLQEAYVTPQ-DGIRLVGELVTVIG
AMIILIFEIPDIFRVGFT--RFFGHTILGGPFHVL------------IIAYASLVLVTMA
MRLTNTSGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFTS---AFYIIFQTEN------------
----PDE------------------LGHFYN------YPMALFSTFEMFLTIIDGP----
---ANYDVDLPFMYSITYAAFAIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGIFGRDYGLG--------------
----------------DRWFL-----RVEDKQDLSQRRARRYAQAFRTRG----------
------------------AH--D--------------PDKGWEE----------------
------------------------------------PRRGRTPGPSL--ALAAP------
------SVSRS---------TSRSSAN---WG-----------------KLRQGALKSEL
RGVVNKGL-------------EEDGWE--YQV-------------------
>SARHA06213_HOG_0033281_Sarcophilusharrisii
-------MGGSS--------------------FKMRGTW-THLREILRTWM-------LR
EQV-WTQS-----------------------------------------------LD---
-----------EANMLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LKAAKENDLCTLKKLVVD---------------------------------GPCD
IHQR------------------GA--LGETALHIASLY---DNLEAAKLLMEVAPE----
---------------------------------------LVNEPMTSELY----------
---------------------------AG--------------------------QTALH
MAIVNQNTNLVRALLARGANISA-RVTGRAFRQN--K-LFYF-GEHPLSFAACVGNEEIV
RLLIE---FGANIRAQDHLGNT-----VLHILVLQPGKN---------------------
--------FACQ---------MYNVLLSYDGQ-GSHLQPLEL------------------
------ISNHQGLTPFKLAGVEGNTV-----------MFNHLMQK--------------R
K-YIQW------THGPLTSTL-----YDLTDIDSWGD-----------------------
----------ELSFLELIVS-TKNRQ----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVNLKWNRFGRPYFYILGAIYVLY------MICFTMCCVYRP
----LKPR-ND---NQT------SSR-DINLFREKCLQESYVTSE-DYIRLIGELVSVIG
AVAILLSEIPDIFRVGFA--RYFGRTILGGPFHVI------------IIIYAGLVLVTMV
MRLTSTSGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLLRFCWLMAVVILGFASGGAAFYVIFQTED------------
----PDE------------------LGHFFD------YPMALFSTFELFLTIIDGP----
---ANYDVDLPFMYSITYAAFAIIATLLMLNLLIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DRWFL-----RVEDRQDPNRQRIQRYAHAFNPLG----------
------------------TD--D--------------LDKDSLNK---------------
------------------------------------LDLTPPCGHHRL-ATATP------
------SISRS---------TTRSSAN---WE-----------------RLRRGTLGINL
RGEINRGL----------E--EEEGRV--YQV-------------------
>HUMAN29666_HOG_0033281_3a_Homosapiens
-------MGGFL--------------------PKAEGPG-SQLQKLLPSFL-------VR
EQD-WDQH-----------------------------------------------LD---
-----------KLHMLQ----------------------------------QKR------
ILES-----------------------------------------P----------L---
-----LRASKENDLSVLRQLLLD---------------------------------CTCD
VRQR------------------GA--LGETALHIAALY---DNLEAALVLMEAAPE----
---------------------------------------LVFEPTTCEAF----------
---------------------------AG--------------------------QTALH
IAVVNQNVNLVRALLTRRASVSA-RATGTAFRHSPRN-LIYF-GEHPLSFAACVNSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDGH-GDHLQPLDL------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
R-HIQW------TYGPLTSIL-----YDLTEIDSWGE-----------------------
----------ELSFLELVVS-SDKRE----------------------------------
------------------------------------------------------------
------ARQILEQTPVKELVSFKWNKYGRPYFCILAALYLLY------MICFTTCCVYRP
----LKFR-GG---NRT------HSR-DITILQQKLLQEAYETRE-DIIRLVGELVSIVG
AVIILLLEIPDIFRVGAS--RYFGKTILGGPFHVI------------IITYASLVLVTMV
MRLTNTNGEVVPMSFALVLGWCSVMYFTRGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTED------------
----PTS------------------LGQFYD------YPMALFTTFELFLTVIDAP----
---ANYDVDLPFMFSIVNFAFTIIATLLMLNLFIAM-MGDTHWRVAQERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGCEFGLG--------------
----------------DRWFL-----RVENHNDQNPLRVLRYVEVFKNSD----------
------------------KE--D--------DQEHP-SEKQPSG----------------
------------------------------------AESGTLARASL--ALPTS------
------SLSRT---------ASQ-SSSHRGWE-----------------ILRQNTL----
-GHLNLGL----------NLSEGDGEE-VYHF-------------------
>PANTR16226_HOG_0033281_3a_Pantroglodytes
-------MGGFL--------------------PKAEGPG-SQLQKLLPSFL-------VR
EQD-WDQH-----------------------------------------------LD---
-----------KLHMLQ----------------------------------QKR------
ILES-----------------------------------------P----------L---
-----LRAAKENDLSVLRQLLLD---------------------------------CTCD
VRQR------------------GA--LGETALHIAALY---DNLEAALVLMEAAPE----
---------------------------------------LVFEPTTCEAF----------
---------------------------AG--------------------------QTALH
IAVVNQNVNLVRALLTRRASVSA-RATGTAFRRSPRN-LIYF-GEHPLSFAACVNSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDGH-GDHLQPLDL------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
R-HIQW------TYGPLTSIL-----YDLTEIDSWGE-----------------------
----------ELSFLELVVS-SDKRE----------------------------------
------------------------------------------------------------
------ARQILEQTPVKELVSFKWNKYGRPYFCILAALYLLY------MICFTTCCVYRP
----LKFR-GG---NRT------HSR-DITILQQKLLQEAYETRE-DIIRLVGELVSIVG
AVIILLLEIPDIFRVGAS--RYFGKTILGGPFHVI------------IITYASLVLVTMV
MRLTNTNGEVVPMSFALVLGWCSVMYFTRGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTED------------
----PTS------------------LGQFYD------YPMALFTTFELFLTVIDAP----
---ANYDVDLPFMFSIVNFAFAIIATLLMLNLFIAM-MGDTHWRVAQERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGCEYGLG--------------
----------------DRWFL-----RVENHNDQNPLRVLRYLEVFKNSD----------
------------------KE--D--------DQEHP-SEKQPSG----------------
------------------------------------AESGTLARASL--ALPTS------
------SLSRT---------ASQ-SSSHRGWE-----------------ILRQNTL----
-GHLNLGL----------NPSEGDGEE-VYHF-------------------
>GORGO19088_HOG_0033281_3a_Gorillagorillagorilla
-------MGGFL--------------------PKAEGPG-SQLQKLLPSFL-------VR
EQD-WDQH-----------------------------------------------LD---
-----------KLHMLQ----------------------------------QKR------
ILES-----------------------------------------P----------L---
-----LRAAKENDLSVLRQLLLD---------------------------------CTCD
VRQR------------------GA--LGETALHIAALY---DNLEAALVLMEAAPE----
---------------------------------------LVFEPTTCEAF----------
---------------------------AG--------------------------QTALH
IAVVNQNVNLVRALLTRRASVSA-RATGTAFRRSPRN-LIYF-GEHPLSFAACVNSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDGH-GDHLQPLDL------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
R-HIQW------TYGPLTSIL-----YDLTEIDSWGE-----------------------
----------ELSFLELVVS-SDKRE----------------------------------
------------------------------------------------------------
------ARQILEQTPVKELVSFKWNKYGRPYFCILAALYLLY------MICFTTCCVYRP
----LKFR-GG---NRT------HSR-DITILQQKLLQEAYETRE-DIIRLVGELVSIVG
AVIILLLEIPDIFRVGAS--RYFGKTILGGPFHVI------------IITYASLVLVTMV
MRLTNTNGEVVPMSFALVLGWCSVMYFTRGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFASGGAAFYIIFQTED------------
----PTS------------------LGQFYD------YPMALFTTFELFLTVIDAP----
---ANYDVDLPFMFSIVNFAFAIIATLLMLNLFIAM-MGDTHWRVAQERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGCEYGLG--------------
----------------DRWFL-----RVENHNDQNPLRVLRYVEVFKNSD----------
------------------KE--D--------DQEHP-SEKQPSG----------------
------------------------------------AESGTLARASL--ALPTS------
------SLSRT---------ASQ-SSSHRGWE-----------------ILRQNTL----
-GHLNLGL----------NLSEGDGEE-VYHF-------------------
>PAPAN12763_HOG_0033281_3a_Papioanubis
-------MGGFL--------------------PKAEGPR-SQLQKLLPSFL-------VR
EQD-WDQH-----------------------------------------------LD---
-----------KLHMLQ----------------------------------QKR------
ILES-----------------------------------------P----------L---
-----LRAAKENDLSVLRQLLLD---------------------------------RTCD
VRQR------------------GA--LGETALHIAALY---DNLEAALVLMEAAPE----
---------------------------------------LVFEPTTCEAF----------
---------------------------AG--------------------------QTALH
IAVVNQNVNLVRALLTRRASVSA-RATGTAFCHSPRN-LIYF-GEHPLSFAACVNSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDGH-GDHMQPLDL------------------
------VPNHQGLTPFKLAAVEGNTV-----------MFQHLMQK--------------R
R-HIQW------TYGPLTSIL-----YDLTEIDSWGE-----------------------
----------ELSFLELVVS-SDKRE----------------------------------
------------------------------------------------------------
------ARQILEQTPVKELVSFKWNKYGRPYFCILAALYLLY------MICFTTCCVYRP
----LKFR-GG---NRT------HSR-DITILQQKLLQEAYETHE-DIIRLVGELVSVTG
AVIILLLEIPDIFRVGAS--RYFGQTILGGPFHVI------------IITYASLVLVTMA
MRLTNTNGEVVPMSFALVLGWCSVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTED------------
----PTS------------------LGQFYD------YPMALFSTFELFLTVIDAP----
---ANYDVDLPFMFSVVNFAFAIIATLLMLNLFIAM-MGDTHWRVAQERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGCEYGLG--------------
----------------DRWFL-----RVENRNDQNPLRVLRYVEAFKNSD----------
------------------KE--D--------DQEHP-SEKQPSG----------------
------------------------------------AESGTLARASL--ALPNS------
------SLSRT---------TSQ-SSSHRGWE-----------------ILRQNTL----
-GHLNLGL----------NLSEGDGEE-VYHF-------------------
>CHLSB10112_HOG_0033281_3a_Chlorocebussabaeus
-------MGGFL--------------------SKAEGPR-SQLQKLLPSFL-------VR
EQD-WDQH-----------------------------------------------LD---
-----------KLHMLQ----------------------------------QKR------
ILES-----------------------------------------P----------L---
-----LRAAKENDLSVLRQLLLD---------------------------------RTCD
VRQR------------------GA--LGETALHIAALY---DNLEAALVLMEAAPE----
---------------------------------------LVFEPTTCEAF----------
---------------------------AG--------------------------QTALH
IAVVNQNVNLVRALLTRRASVSA-RATGTAFRRSPHN-LIYF-GEHPLSFAACVNSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDGH-RDHMQPLDL------------------
------VPNHQGLTPFKLAAVEGNTV-----------MFQHLMQK--------------R
R-HIQW------TYGPLTSIL-----YDLTEIDSWGE-----------------------
----------ELSFLELVVS-SDKRE----------------------------------
------------------------------------------------------------
------ARQILEQTPVKELVSFKWNKYGRPYFCILAALYLLY------MICFTTCCVYRP
----LKFR-GG---NRT------HSR-DITILQQKLLQEAYETHE-DVIRLVGELVSVTG
AVIILLLEIPDIFRVGAS--RYFGQTILGGPFHVI------------IITYASLVLVTMA
MRLTNTNGEVVPMSFALVLGWCSVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFASGGAAFYIIFQTED------------
----PTS------------------LGQFYD------YPMALFSTFELFLTVIDAP----
---ANYDVDLPFMFSVVNFAFAIIATLLMLNLFIAM-MGDTHWRVAQERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGCEYGLG--------------
----------------DRWFL-----RVENHNDQNPLRVLRYVEAFKNSD----------
------------------KE--D--------DQEHP-SEKQPSG----------------
------------------------------------AESGTLARASL--ALPNS------
------SLSRT---------TSQ-SSSHRGWE-----------------ILRQNTL----
-GHLDLGL----------NLSEGDGEE-VYHF-------------------
>NOMLE10827_HOG_0033281_3a_Nomascusleucogenys
-------MGGFL--------------------PKAERPG-SQLQKLLPSFL-------VR
QED-WDQH-----------------------------------------------LD---
-----------KLHMLQ----------------------------------QKR------
ILES-----------------------------------------P----------L---
-----LRAAKENDLSVLRQLLLD---------------------------------RTCD
IRQR------------------GA--LGETALHIAALY---DNLEAAFVLMEAAPE----
---------------------------------------LVFEPTTCEAF----------
---------------------------AG--------------------------QTALH
IAVVNQNVNLVRALLTHRASVSA-RATGTAFRRSPRN-LIYF-GEHPLSFAACVNNEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDGH-GDHLQPLDL------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
R-HIQW------TYGPLTSIL-----YDLTEIDSWGE-----------------------
----------ELSFLELVVS-SDKRE----------------------------------
------------------------------------------------------------
------ARQILEQTPVKELVSFKWNKYGRPYFCIMAALYLLY------MICFTMCCVYRP
----LKFR-GG---NRT------HSR-DITILQQKLLQEAYETRE-DIIRLVGELVSIAG
AVIILLLEIPDIFRVGVS--RYFGQTILGGPFHVI------------IITYACLVLVTMV
MRITNTNGEVVPMSFALVLGWCSVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTED------------
----PTS------------------LGHFYD------YPMALFSTFELFLTVIDAP----
---ANYDVDLPFMFSIVNFAFAIIATLLMLNLFIAM-MGDTHWRVAQERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGCEYGLG--------------
----------------DRWFL-----RVENHNDQNPLRVLRYVEVFKNSD----------
------------------KE--D--------GQEHP-SEKQPSG----------------
------------------------------------AESGTLARASL--ALPTS------
------SLSRT---------VSQ-SSSHRGWE-----------------ILRQNTL----
-GHLNLGL----------NLSDGDGEE-VYHF-------------------
>Tarsier_TRPV5
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
IRES-----------------------------------------L----------L---
-----LRAAKENDLFCLRQLLLD---------------------------------RTCD
IRQR------------------XX--XXXXXXXXXXXX---XXXXXXXXXXXXXXX----
---------------------------------------XXXXXXXXXXX----------
---------------------------XX--------------------------QTALH
IAIVNQNVSLVRALLAHGASVSA-RATGTAFRRSSHN-LIYF-XXXXXXXXXXXXXXXXX
XXXXX---XXXXXXXXXXXXXX-----XXXXXXXXXXXX---------------------
--------XXXX---------XXXXXXXXXXX-XXXXXXXXX------------------
------XXXXXXXXXXXXXXXXXXXX-----------MFQHLMQK--------------R
K-HIQW------TYGPLTSIL-----YDLTEIDSWGE-----------------------
----------ELSFLELVVS-SNKRE----------------------------------
------------------------------------------------------------
------ARQILEQTPVKELVSFKWNKYGRPYFCILGALYLLY------MICFTMCCVYRP
----LKFR-GS---NRT------NSR-DNTILQQKLLQEAYVTHQ-DIIRLVGELVSILG
AVIILFLEIPDIFRVGAS--RYFGQTILGGPFHVI------------IITYAFMVLVTMV
MRLTNTNGEVVPMSFALVLGWCSVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTED------------
----PTN------------------LGEFYD------YPMALFSTFELFLTIIDAP----
---ANYDVNLPFMFSIVNFAFAIIATLLMLNLFIAM-MGDTHWRVAQERDELWRAQVVAT
TVMLERKM--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DRWFL-----RVENHRDQNPLRVLRYVEAFKSSD----------
------------------KE--D--------GQENL-SEKQPSV----------------
------------------------------------TGSGILARASL--ALPNP------
------SLSRT---------TSQSSSSHRGWE-----------------ILRQNTR----
-GHLNLGL----------DLGEGDGEE-VYHF-------------------
>OTOGA10499_HOG_0033281_3a_Otolemurgarnettii
-------MEACP--------------------PKAKGPW-LQPQRCLFSWM-------VR
EED-WDKR-----------------------------------------------MD---
-----------QAYMLQ----------------------------------QKR------
IQES-----------------------------------------P----------L---
-----LQAAKENDLFVLKQLLLN---------------------------------QACN
FWQR------------------GG--LGETALHVAALY---DNLEAAVVLMEAAPE----
---------------------------------------LAKEPTLCEPF----------
---------------------------VG--------------------------QTALH
IAVVNQNVNLVRALLTHGASVSA-RATGAAFCRSPRN-LIYF-GEHPLSFAACVGSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILVLQPNKT---------------------
--------FACQ---------MYNLLLSYDCL-KDHLLPLEA------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLIQK--------------R
K-HIQW------TWGPLTSTL-----YDLTEIDSWGE-----------------------
----------ELSFLELVVS-SNKRE----------------------------------
------------------------------------------------------------
------ARQILEQTPVKELVSLKWNKYGRPYFCMLGALYLLY------MVCFTTCCIYRP
----LKFR-GS---NRT------NSR-DNTILQQKLLQEAYVTHH-DMIRLVGELFTVIG
AVIILLLEIPDIFRVGAS--RYFGQTVLGGPFHVI------------IITYASLVLVTMV
MRITNTNGEVVPMSLALVLGWCSVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFASGGTAFYIIFQTED------------
----PTN------------------LGEFYD------YPMALFSTFELFLTIIDAP----
---ANYEVNLPFMFGIVNFAFAIIATLLMLNLFIAM-MGDTHWRVAQERDELWRAQVVAT
TVVLERKM--------PR-----------FLWPR-SGICGLQYGLG--------------
----------------DRWFL-----RVENHTTQNPLRVMRYVEAFKGPD----------
------------------KE--D--------GQEQF-SEKQPSM----------------
------------------------------------AESGTLARASL--ALPTP------
------SLSRT---------TSR-SSSHRGWE-----------------ILRRNAM----
-GHVNLGL----------DLGEGEGEE-VYRL-------------------
>MICMU10182_HOG_0033281_3a_Microcebusmurinus
-------MGACP--------------------PKAKGPW-LQPQTPLLSWL-------FR
EQD-WDQH-----------------------------------------------LD---
-----------QAYMLQ----------------------------------QKR------
DPES-----------------------------------------P----------L---
-----LAAKK--DLFALK------------------------------------------
------------------------------------------------------------
-------------------------------------------XTLYEPL----------
---------------------------VG--------------------------QTALH
IAIVNQNVNLVRALLAHGASVSA-RATGAAFRRSPQN-LIYF-GEHPLSFAACVGSEEIV
RLLIE---HGANIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FAC-------------------------------------------------
-------------------------X-----------MFQHLMQK--------------R
K-HIQW------TYGPLTSTL-----YDLTEIDSWGE-----------------------
----------ELSFLELVVS-SSKRE----------------------------------
------------------------------------------------------------
------ARQILEQTPVKELVSFKWNKYGRPYFCVLGALYLLY------MACFTACCIYRP
----LKFR-GS---NRT------HSR-DNTILQQKLLQEAYVTHQ-DIVRLVGELVTILG
AVIILLLEIPDIFRVGAS--RYFGQTILGGPFHVI------------IITYAFMVLVTMV
MRLTNTDGEVVPMSLALVLGWCSVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTED------------
----PTN------------------LGEFYD------YPMALFSTFELFLTIIDAP----
---ANYEVNLPFMFGIVNFAFAIIATLLMLNLFIAM-MGDTHWRVAQERDELWRAQVVAT
TVMLERKM--------PR-----------FLWPR-SGICGFHYGLG--------------
----------------DRWFL-----RVESHHSQSALRVLRYVEAFKGPD----------
------------------KE--D--------GQEQF-SEKQPSV----------------
------------------------------------AESGTLARASL--ALPTP------
------SLSRT---------TSR-SSSHRGWE-----------------VLRRNTL----
-GHVNLVL----------DVGEGDGEE-VYRL-------------------
>MOUSE18363_HOG_0033281_3a_Musmusculus
-------MG-------------------------AKTPW-IQLQKLL-NWW-------VR
DQD-WNQH-----------------------------------------------VD---
-----------QLHMLQ----------------------------------QKS------
IWES-----------------------------------------P----------L---
-----LRAAKENDMCTLKKLQHD---------------------------------QNCD
FRQR------------------GA--LGETALHVAALY---DNLDAAIMLMEAAPY----
---------------------------------------LVTESTLCEPF----------
---------------------------VG--------------------------QTALH
IAVMNQNVNLVRALLARGASASA-RATGSAFHRSSHN-LIYY-GEHPLSFAACVGSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILVLQPNKT---------------------
--------FACQ---------MYNLLLSYDG--GDHLKSLEL------------------
------VPNNQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-RIQW------SFGPLTSSL-----YDLTEIDSWGE-----------------------
----------ELSFLELVVS-SKKKE----------------------------------
------------------------------------------------------------
------ARQILEQTPVKELVSLKWKKYGQPYFCLLGALYIFY------MVCFTTCCVYRP
----LKFR-DA---NRT------HVR-DNTIMEQKSLQEAYVTYQ-DKIRLVGELVTVIG
AVIILLLEIPDIFRVGAS--RYFGQTVLGGPFHVI------------IITYASLVLLTMA
MRLTNVNGEVVPMSMALVLGWCSVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLLRFCWLMAMVILGFAS---AFYIIFQTED------------
----PDN------------------LGEFSD------YPTAMFSTFELFLTIIDGP----
---ANYRVDLPFMYSVTYATFAIIATLLMLNLFIAM-MGDTHWRVAQERDELWRAQVVAT
TVMLERKM--------PR-----------FLWPR-SGICGCEYGLG--------------
----------------DRWFL-----RVEHHQEQNPYRVLRYVEAFKSSD----------
------------------KE--E--------VQEQL-SEKQPSG----------------
------------------------------------TETGTLARGSV--VLQTP------
------PLSRT---------TSLSSNSHRGWE-----------------ILRRNTL----
-GHLNLGL----------DPGEGDGEE-IYQF-------------------
>RATNO14980_HOG_0033281_3a_Rattusnorvegicus
-------MG-------------------------VKKPW-IQLQKRL-NWW-------VR
EQD-WNQH-----------------------------------------------VD---
-----------QLHMLQ----------------------------------QKS------
IWES-----------------------------------------P----------L---
-----LRAAKENDMCTLKRLQHD---------------------------------QNCD
FRQR------------------GA--LGETALHVAALY---DNLDAAIMLMETAPY----
---------------------------------------LVTESTLCEPF----------
---------------------------VG--------------------------QTALH
IAIMNQNVNLVRALLARGASASA-RATGSAFHRSSHN-LIYY-GEHPLSFAACVGSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILVLQPNKT---------------------
--------FACQ---------MYNLLLSHDG--GDHLKSLEL------------------
------VPNNQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HIQW------SLGPLTSSI-----YDLTEIDSWGE-----------------------
----------DLSFLELVVS-SKKKE----------------------------------
------------------------------------------------------------
------ARQILEQTPVKELVSLKWKKYGQPYFCLLGMLYIFY------MICFTTCCVYRP
----LKFR-DA---NRT------HVR-DNTVLEQKPLQEAYVTYQ-DKVRLVGELVTVIG
AVVILLIEIPDIFRVGAS--RYFGHTVLGGPFHVI------------IITYASLVLLIMV
MRLTSMNGEVVPISMALVLGWCSVMYFSRGFQMLGPFTIMIQK-----------------
-------------MIFGDLLRFCWLMAMVILGFAS---AFYIIFQTED------------
----PES------------------LGEFSD------YPTAMFSTFELFLTIIDGP----
---ANYSVDLPFMYHLTYFAFAIIATLLMLNLFIAM-MGDTHWRVAQERDELWRAQVVAT
TVMLERKM--------PR-----------FLWPR-SGICGCEYGLG--------------
----------------DRWFL-----RVEHHQEQNPYRVLRYVEAFKSSD----------
------------------KE--E--------VQEQL-SEKQPSG----------------
------------------------------------TETGTLARGSV--VLQTP------
------PLSRT---------TSLSSNSHRGWE-----------------ILRRNTL----
-GHLNLGQ----------DLGEGDGEE-IYHF-------------------
>SPETR02471_HOG_0033281_3a_Spermophilustridecemlineatus
-------MG-------------------------AKGPW-IQLQKFLASWL-------VG
EQD-WDQH-----------------------------------------------LD---
-----------QVYMLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LQAAKENDLCTLKKLLLE---------------------------------QNCD
FRQR------------------GA--LGETALHVAALY---DNLEAAMVLMEAAPD----
---------------------------------------LVQEPTVCEPF----------
---------------------------IG--------------------------QTALH
IAVMNQNVNLVRALLSHGASVSA-RATGTAFQRSPHN-LIYY-GEHPLSFAACVGSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDG--GDHLQPLEL------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLMQR--------------R
K-HIQW------TYGPLTSTL-----YDLTEIDSWGE-----------------------
----------ELSFLELVVS-SKKRE----------------------------------
------------------------------------------------------------
------ARQILEQTPVKELVSFKWKKYGQPYFCILGALYILY------MMCFTTCCVYRP
----LKFR-VG---NRT------NPR-DNIIFQQKLLQEAYVTYQ-DHIRLVGELVTVIG
AVIILLLEIPDIFRVGAS--RYFGQTILGGPFHVI------------IITYASLVLVTMV
MRLTNTNGEVVPISLALVLGWCSVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAMVILGFASGGAAFCIIFQTED------------
----PAN------------------LGEFSD------YPTALFSTFELFLTIIDGP----
---ANYNVDLPFMYNLAYAAFAIIATLLMLNLFIAM-MGDTHWRVAQERDELWRAQVVAT
TVMLERKM--------PR-----------FLWPR-SGICGCEYGLG--------------
----------------DRWFL-----RVENHHDQNPLRVLRYVEAFKCSD----------
------------------KE--D--------GQEQL-SEKQPSV----------------
------------------------------------TEVGTLARASL--VLQTP------
------SLSRT---------TSQSSNSHRGWE-----------------ILRRNTL----
-AHLNLGL----------DLGEGDGEE-VYHF-------------------
>DIPOR07371_HOG_0033281_3a_Dipodomysordii
-------MG-------------------------AKRPW-IQLQKLL-SWL-------TG
EQD-WDQN-----------------------------------------------LD---
-----------NLYMLQ----------------------------------QKR------
IWEA-----------------------------------------P----------L---
-----LRAAKEHDLCTLKRLLLD---------------------------------PKCD
FQQR------------------GA--LGETALHIAALY---DNLEAAMALMEAAPD----
---------------------------------------LVTEPIVCEPF----------
---------------------------VG--------------------------QTALH
IAVMNQNVNLVRALLARGASVSA-RATGFAFHLSPHN-LIYY-GEHPLSFAACVGSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDG--GDHLQSLEL------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HIQW------TYGPLTSTL-----YDLTEIDSWRE-----------------------
----------ELSFLELVVS-SKKRE----------------------------------
------------------------------------------------------------
------ARQILEQTPVKELVSLKWKKYGRPYFCVLGALYILY------MICFTACCVYRP
----LKFR-DG---NRT------SSR-DNTILEQKLLQ----------------------
-----------------------------------------------XITYASLVLVTMV
MRLTNVNGEVVPISLALVLGWCSVMYFTRGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAMVILGFAS---AFYIIFQTED------------
----PAN------------------LGEFSN------YPTALFSTFELFLTIVDAP----
---ANYSVDLPFMYSITYAAFAIIATLLMLNLFIAM-MGDTHWRVAQERDELWRAQV---
--MLERKM--------PR-----------FLWPR-SGICGCDYGLG--------------
----------------DRWFL-----RVESHHDQNPFRMLRYVEAFKCPD----------
------------------KE--D--------GQEQL-SEKRPSI----------------
------------------------------------AESEILARSSL--IFQTP------
------SLSRT---------TSQSSSSHRGWE-----------------ILRRNTL----
-GHLNIGL----------DLGEGDGEE-IYHF-------------------
>RABIT03901_HOG_0033281_3a_Oryctolaguscuniculus
-------MGACP--------------------PKAKGPW-AQLQKLLISWP-------VG
EQD-WEQY-----------------------------------------------RD---
-----------RVNMLQ----------------------------------QER------
IRDS-----------------------------------------P----------L---
-----LQAAKENDLRLLKILLLN---------------------------------QSCD
FQQR------------------GA--VGETALHVAALY---DNLEAATLLMEAAPE----
---------------------------------------LAKEPALCEPF----------
---------------------------VG--------------------------QTALH
IAVMNQNLNLVRALLARGASVSA-RATGAAFRRSPHN-LIYY-GEHPLSFAACVGSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDEH-SDHLQSLEL------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HVQW------TCGPLTSTL-----YDLTEIDSWGE-----------------------
----------ELSFLELVVS-SKKRE----------------------------------
------------------------------------------------------------
------ARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILY------MICFTTCCIYRP
----LKLR-DD---NRT------DPR-DITILQQKLLQEAYVTHQ-DNIRLVGELVTVTG
AVIILLLEIPDIFRVGAS--RYFGQTILGGPFHVI------------IITYASLVLLTMV
MRLTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFHITFQTED------------
----PNN------------------LGEFSD------YPTALFSTFELFLTIIDGP----
---ANYSVDLPFMYCITYAAFAIIATLLMLNLFIAM-MGDTHWRVAQERDELWRAQVVAT
TVMLERKM--------PR-----------FLWPR-SGICGYEYGLG--------------
----------------DRWFL-----RVENHHDQNPLRVLRYVEAFKCSD----------
------------------KE--D--------GQEQL-SEKRPST----------------
------------------------------------VESGMLSRASV--AFQTP------
------SLSRT---------TSQSSNSHRGWE-----------------ILRRNTL----
-GHLNLGL----------DLGEGDGEE-VYHF-------------------
>OCHPR03847_HOG_0033281_3a_Ochotonaprinceps
-------MGACP--------------------PKAMGPW-VQLQKLLTSWL-------AG
GQD-WEWH-----------------------------------------------RD---
-----------QVNMLQ----------------------------------QKR------
IRDS-----------------------------------------P----------L---
-----L-AAKENDLVLLKILLVN---------------------------------QSCD
FQQR------------------GA--VGETALHVAALY---DNMEAAMMVMKAAPE----
---------------------------------------LAKEPALYEPF----------
---------------------------VG--------------------------QTALH
IAVMNQNLNLVRALLARGACVSA-RATGAAFRRSPHN-LIYY-GEHPLSFAACVGNEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDEH-NDDPQSLEF------------------
------VPNHEGLTPFKLAGVEGNTV----------------------------------
------------------------------------------------------------
-------------------------X----------------------------------
------------------------------------------------------------
------ARQILEQTPVKELVSFKWKKYGKPYFCILATLYILY------MICFTTCCIYRP
----LKLR-DS---NRT------DPR-DITILQQKLLQEAYMTHQ-DNIRLVGELVTVTG
AVIILLLEIPDIFRVGAS--RYFGQTILGGPFHVI------------IITYASLILLTMA
MRLTNMNGEVVPLSLALVLGWCSVMYFARGFQMLGPFTIMIQK-----------------
-------------MVFGDLLRFCWLMAVVILGFAT---AFHIIFQTED------------
----PSN------------------LGEFSD------YPTALFSTFELFLTIIDGP----
---ANYD-DLPFMYCITYAA---IATLLM--------------------------XVVAT
TVMLERKM--------PR-----------FLWPR-SGVCGYEYGLG--------------
-----------------RWFL-----RVENYNDQNPLRVLRYVEAFKPSD----------
------------------KE--D--------GQEQL-PAKRPSM----------------
------------------------------------AESWILGRAST--AFQTP------
------SLSRT---------TSQSSNSHRGWE-----------------ILRRNTL----
-GHLNLGL----------DLSEGDGEE-VYHF-------------------
>CANFA04442_HOG_0033281_4a_Canisfamiliaris
-------MGAPL--------------------PKAEGPW-VQLQKLLASWL-------VR
EQD-WDQH-----------------------------------------------VD---
-----------EAHMLQ----------------------------------QKR------
IQES-----------------------------------------P----------L---
-----LQAAKENDLCVLKKLLLD---------------------------------RNCD
FRQR------------------GA--LGETALHIAALY---DNLEAAMVLMEAAPE----
---------------------------------------LVKEPTLCEPF----------
---------------------------VG--------------------------QTALH
IAIVNQNVNLVRALLARGASVSA-RATGTAFRRSPRN-LIYF-GEHPLSFAACVGSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDGR-RDHLQSLDL------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HIQW------TYGPLTSTL-----YDLTEIDSWGE-----------------------
----------DVSFLELVVS-SKKRE----------------------------------
------------------------------------------------------------
------ARQILEQTPVKQLVSFKWRKYGQRYFYILGALYTLY------MICFTTCCIYRP
----LKFR-MG---NRT------DPR-DNTVLQQKLLQEAYVTQQ-DKIRLVGELVTITG
AVIILLLEIPDIFRVGAS--RYFGQTILGGPFHVI------------IIIYACMVLVTMV
MRLSNMNGEMVPMSIALVLGWCSVMYFARGFQMLGPFSIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYVIFQTED------------
----PAN------------------LGQFYD------YPMALFSTFELFLTVIDGP----
---ANYEVNLPFMFGIVYFAFTIIATLLMLNLFIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGCQYGLG--------------
----------------DRWFL-----RVENHHDQNPLRVLRYVEAFKGSD----------
------------------KE--D--------GQEQL-SDKQPSVSV--------------
------------------------------------TESGTLARASL--APPTP------
------SLSRT---------TSH-SSSHRGWE-----------------ILRRNTL----
-GHVNLGL----------DLGEGDGEDNIYHL-------------------
>MUSPF00878_HOG_0033281_4a_Mustelaputoriusfuro
-------MGAPP--------------------PKTEGPW-VQLQKLLASWL-------VR
EPD-WDQR-----------------------------------------------VD---
-----------EAHMLQ----------------------------------QKR------
IQEF-----------------------------------------P----------L---
-----LQAAKENDLCVLKKLLLD---------------------------------RNCD
FRQR------------------GA--LGETALHIAALY---DNLEAAMVLVEAAPE----
---------------------------------------LVKEPTLCEPF----------
---------------------------VG--------------------------QTALH
IAIVNQNVNLVRTLLAHGASVSA-RATGTAFHRSPRN-LIYF-GEHPLSFAACMGSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDGR-RDHLQSLDL------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HIQW------TYGPLTSTL-----YDLTEIDSWGE-----------------------
----------DVSFLELVVS-SKKRE----------------------------------
------------------------------------------------------------
------ARQILEQTPVKQLVSFKWKKYGRRYFYILGALYTLY------MICFTTCCIYRP
----LKFR-MG---NRT------DPR-DNTVLEQKLLQEAYVTQQ-DKIRLVGELVTVIG
AVIILLLEIPDIFRVGAS--RYFGQTILGGPFHVI------------IIIYACMVLVTMV
MRLSNMNGEMVPMSIALVLGWCSVMYFARGFQMLGPFSIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFASGGAAFYVIFQTED------------
----PAN------------------LGQFYD------YPMALFSTFELFLTVIDGP----
---ANYEVNLPFMFGIVYFAFTIIATLLMLNLFIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------FLWPR-SGICGYQYGLG--------------
----------------DRWFL-----RVENHQDQNPLRVLRYVEAFKGSD----------
------------------KE--D--------GQEQL-TEKQPSVSA--------------
------------------------------------TESGTLARASL--TPPTP------
------SLSRT---------TSH-SSSHRGWE-----------------ILRRNTL----
-GHVNLGL----------DLGEGDGEDNIYHL-------------------
>AILME07708_HOG_0033281_4a_Ailuropodamelanoleuca
-------MGAPP--------------------SKAEGPW-VQLQKLLASWL-------VR
GQD-WDQH-----------------------------------------------VD---
-----------EAHMLQ----------------------------------QKR------
IQDS-----------------------------------------P----------L---
-----LQAAKENDLCVLKKLLLD---------------------------------RSCD
FRQR------------------GA--LGETALHIAALY---DNLEAAMVLIEAAPE----
---------------------------------------LVKEPTLCEPF----------
---------------------------VG--------------------------QTALH
IAIVNQNVNLVRALLAHGASVSA-RATGTAFRRSPRN-LIYF-GEHPLSFAACVGSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHVLILQPNKT---------------------
--------FACQ---------MYNLLLSYDGR-GDHLQPLDL------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HIQW------TYGPLTSTL-----YDLTEIDSWGE-----------------------
----------DVSFLELVVS-SKKRE----------------------------------
------------------------------------------------------------
------ARQILEQTPVKQLVSFKWKKYGQRYFYVLGAVYALY------VICFTACCVYRP
----LKLR-TG---NRT------DPR-DNTVLQQKLLQEAYVTQQ-DKIRLVGELVTIAG
AVIILLLEIPDIFRVGAS--RYFGQTVLGGPFHVI------------IIIYACMVLVTMV
MRLSNMNGEMVPMSIALVLGWCSVMYFARGFQMLGPFSIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFASGGAAFYVIFQTED------------
----PAN------------------LGQFYD------YPMALFSTFELFLTVIDGP----
---ANYEVNLPFMFGIVYFAFTIIATLLMLNLFIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------FLWPR-SGICGCQYGLG--------------
----------------DRWFL-----RVENHHDQNPLRVLRYVEAFKGSD----------
------------------KE--D--------GQEQL-SEKQPSVSA--------------
------------------------------------IESGTIARASL--APPTP------
------SLSRT---------TSH-SSSHRGWE-----------------ILRRNTL----
-GHVNLGL----------DLGEGDGEDNIYHL-------------------
>FELCA02738_HOG_0033281_4a_Feliscatus
-------MGSPP--------------------PKAEGPR-VQLQKLLASWL-------LR
EQD-WDQH-----------------------------------------------LD---
-----------EAHMLQ----------------------------------QKR------
IRES-----------------------------------------P----------L---
-----LQAAKENDLCALKKLLLD---------------------------------RSCD
FRQR------------------GA--LGETALHIAALY---DNLEAAVVLIEAAPE----
---------------------------------------LVKEPTLCEPF----------
---------------------------VG--------------------------QTALH
IAIVNQNVNLVRALLAHGASVSA-RATGMAFRHSPRN-LIYF-GEHPLSFAACVGSEEMV
RLLIE---HGADIRAQDSLGKSWGPEGRGHPEVGQGSQR---------------------
---------GLQ---------RNGXLLSYDGR-RDHLQSLDL------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HIQW------TYGPLTSTL-----YDLTEIDSWGE-----------------------
----------DMSFLELVIS-SKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVSLKWKRYGQRYFHILGALYMLY------MICFTACCIYRP
----LKFR-LG---NRT------DPR-DNTVLQQKLLQEAYVTQQ-DKIRLVGELVTIMG
AVIILLLEIPDIFRVGAS--RYFGQTILGGPFHVI------------IITYACMVLVTMV
MRLSNMNGEMVPMSIALVLGWCSVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYVIFQTED------------
----PSN------------------LGQFYD------YPMALFSTFELFLTVIDGP----
---ANYEVNLPFMFGIVYFAFTIIATLLMLNLFIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------FLWPR-SGICGCQYGLG--------------
----------------DRWFL-----RVENHHDQNPLRVLRYVEAFKGSD----------
------------------KE--D--------GQEQL-SEKQPSVSV--------------
------------------------------------IESGTPARASL--APPTP------
------SLSRT---------TSHSSSSHRGWE-----------------ILRRNTL----
-GHFNLGL----------DLGEGDGEENIYHL-------------------
>HORSE14871_HOG_0033281_4a_Equuscaballus
-------MGAPP--------------------AEARGPW-IQLQTFLTSWL-------VR
EQD-WDQQ-----------------------------------------------VD---
-----------EAHMLQ----------------------------------QKR------
IRDS-----------------------------------------P----------L---
-----LQAAKENDLCVLKELLLD---------------------------------RACA
FRQR------------------GA--LGETALHIAALY---DNLEAAMVLMEASPE----
---------------------------------------LVKEPVMCEPF----------
---------------------------VG--------------------------QTALH
IAVMNQNVNLVRALLAHGASVSA-RATGTAFHRSPHN-LIYF-GEHPLSFAACVGSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILIFQPNKT---------------------
--------FACQ---------MYNLLLSYDGH-GDHLQSLDL------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLIQK--------------R
K-HIQW------TCGPLTSTL-----YDLTEIDSWGE-----------------------
----------EVSFLELVVS-SKKRE----------------------------------
------------------------------------------------------------
------ARQILEQTPVRQLVSFKWKKYGRRYFCLLGALYVLY------MTCFTMCCVHRP
----LKFR-SV---NRT------NSR-DNTILQQKLLQEAYETHQ-DKIRMVGELVTVVG
AVIILLLEIPDIFRVGVS--RYFGQTVLGGPFHVI------------IITYAFLVLVTMV
MRLCNMNGEVVPMSIALVLGWCSIMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVIVGFAS---AFFVIFQTED------------
----PNN------------------LGQFYD------YTMALFSTFELFLTLIDGP----
---ANYDVNLPFMFSIVYFAFAIIATLLMLNLFIAM-MGDTHWRVAHEQDELWRAQVVAT
TVMLERKL--------PR-----------FLWPR-SGICGCKYGLG--------------
----------------DRWFL-----RVENHHDQNPLRVLRYVEAFKSSD----------
------------------KE--D--------GQENL-SEKQPSV----------------
------------------------------------VESGTQARTSL--FLPTP------
------SLSRN---------TSRSSSSHRGWE-----------------ILRRNTL----
-GHLNLGL----------DLGEEDGEENIYRL-------------------
>Tupaia_belangeri_TRPV5_Tree_Shrew_ENSTBET00000012746
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
IRES-----------------------------------------P----------L---
-----LRAAKENDLCVLKKFLLD---------------------------------KTND
FQQR------------------GA--LGETALHIAALY---DNLEAAMLLIEAAPE----
---------------------------------------LVKEPTMCEPF----------
---------------------------VG--------------------------HTALH
IAVVNQNVNLVRALLAHGARVSA-RATGTAFHRSPH--LIYF-GEHPLSFAACVGSEEIV
RLLIE---HGADIRAQDSLXXX-----XXXXXXXXXXXX---------------------
--------XXXX---------XXXXXXXXXXX-XXXXXXXXX------------------
------XXXXXXXXXXXXXXXXXXXX-----------MFQHLMQK--------------R
K-HIQW------TYGPLTSTL-----YDVTEIDSWGE-----------------------
----------ELSFLELVVS-SKKRE----------------------------------
------------------------------------------------------------
------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX------XXXXXXXXXXXX
----XXXX-XX---XXX------XXX-XXXXXXXXXXXEAYVTYE-DNVRLVGELVTITG
AVIILLVEIPDIFRVGAS--RYFGQTVLGGPFHVI------------IITYAFMVLVTMV
MRLTNADGEVVPMSFALVLGWCSVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTED------------
----PNN------------------LGQFYD------YPMSLFSTFELFLTIIDGP----
---ANYNVNLPFMFCIVYFAFAIIATLLMLNLFIAM-MGDTHWRVAQERDELWRAQVVAT
TLMLERKM--------PR-----------FLWPR-SGTCGCEYGLG--------------
----------------DRWFL-----RVENHHDQNPLRVLRYVEAFKSSE----------
------------------KE--D--------GPEHL-SEKQHSL----------------
------------------------------------TESGALTRGSL--TVPSP------
------PLSRT---------TSRSSSSHRGWE-----------------ILRRNTL----
-GHLNFGM----------DFGEGDGEEV-----------------------
>Sloth_TRPV5
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
IQES-----------------------------------------P----------L---
-----FRAAKENDLCGLKKLLLE---------------------------------GTCN
IRQK------------------XX--XXXXXXXXXXXX---XXXXXXXXXXXXXXX----
---------------------------------------XXXXXXXXXXX----------
---------------------------XX--------------------------XXXLH
IAVVNQNVNLVRALLAHGASVSA-RATGLAFRHSPRN-LIYF-GEHPLSFAACVGSEEIV
RLLIE---HGADIRAQDYLGNT-----VLHILILQPRKT---------------------
--------FACQ---------MYNLLLSYDRR-GDHLKSLDL------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLIQK--------------R
K-HIQW------TYGPLTSTL-----YDLTEIDDSGE-----------------------
----------ELSFLELVVS-SKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVSLKWRQYGRPYFCILGALYVLY------MICFTMCCVYRP
----LKLR-DD---NRT------DSR-DNTILQQKLLQEAYVTYQ-DEIRLVGELVTIIG
AVIILLLEIPDIFRVGAT--CYFGQTVLGGPFHVI------------IITYACLVLMIMV
MRLTNITGEVVPMSFALVLGWCSVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMVVVIVGFAS---AFYIIFQTED------------
----PVN------------------LGQFYD------YPMALFSTFELFLTVIDGP----
---ANYDVNLPFMFGVVYFAFVIIATLLMINLFIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGREYGLG--------------
----------------DRWYL------VENHHDQNSLRVLRYVEAFKGSD----------
------------------KE--D--------GREHI-SEKLSSV----------------
------------------------------------VESGTLARTSL--AIPTP------
------SLSRT---------TSHSSSIHRGWE-----------------IIRRNTV----
-GHLNL---------------------------------------------
>Armadillo_TRPV5
-------MGAPQ--------------------PKEKGPW-LHLQRLLTSWL-------GR
EQD-WDHH-----------------------------------------------IE---
-----------KAYMLQ----------------------------------QKS------
IQEI-----------------------------------------P----------L---
-----FQAAKENDLHVLKKLLLE---------------------------------QTCD
LRQR------------------GA--LGETALHIAALY---DNLEAAMVMMEAVPE----
---------------------------------------LVKESTLCEPF----------
---------------------------VG--------------------------QTALH
IAVMNQNVNLVRALLAHGASVSA-RATGMAFRRSPRN-LIYF-GEHPLSFAACVGNEEIV
RLLIE---HGADIRAQDALGNT-----VLHILVLQLNKT---------------------
--------FACQ---------MYNLLLSFDRH-RDHPKSLDL------------------
------VPNHKGLTPFKLAGVEGNTV-----------MFQHLIQK--------------R
R-HIQW------TYGPLTSTL-----YDLTEIDSWGE-----------------------
----------ELPFLELVVS-SKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVSFKWNQYGRPYFCILGALYVLY------MICFTMCCVYRP
----LKSR-DG---NRT------DSR-DNTLLQQKLLQEAYVTYQ-DDIRLIGELVTIIG
AVTILLLEIPDIFRVGAT--CYFGQTVLGGPFHVI------------IITYACMVLVIMV
MRLTNVSGEVVPMSFALVLGWCSVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMVVVILGFASGGAAFYIIFQTED------------
----PTN------------------LGHFYD------YPMALFSTFELFLTVIDGP----
---ANYEVNLPFMFGVVYFAFTIIATLLMLNLFIAM-MGDTHWRVAHEQGELWRAQVVAT
TVMLERKL--------PR-----------WLWPR-SGICGLEYGLG--------------
----------------DHWFL-----RVENYHDQNPLRVLRYVEAFKSSD----------
------------------QE--D--------GQEHL-SEKILSV----------------
------------------------------------AESGTLARASR--AIPTP------
------SLSRT---------TSHNSSSHQCWE-----------------IIRYNTW----
-GHLNLGL----------DLGEGDGEERVYHI-------------------
>BOVIN15324_HOG_0033281_4a_Bostaurus
-------MGAPP--------------------SKARGLW-IQLQKLLTSWL-------VG
QQD-WDQR-----------------------------------------------LD---
-----------EMYMLQ----------------------------------QQK------
IRES-----------------------------------------P----------L---
-----LRAAKDNDLCVLKKLLLD---------------------------------RNCD
FRQR------------------GA--VGETALHVAALY---DNLEAAMVLMEAAPE----
---------------------------------------LVKEPAICEPF----------
---------------------------VG--------------------------QTALH
IAVMNRNVNLVKALLAQGASVSA-RAIGSAFRLTPHN-LIYF-GEHPLSFAACMGSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILVLQPNKT---------------------
--------FACQ---------MYNLLLSYDRR-GDHLQSLDL------------------
------MLNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-YIQW------TCGPLTSTL-----YDLTEIDSWGE-----------------------
----------DVSFLELVVS-SKKRE----------------------------------
------------------------------------------------------------
------ARQILEQTPVKQLVNFKWRKYGRPYFCILGALYVLY------MICFTMCCIHRP
----LKAR-SG---NRT------DSR-DITVFQQKLLQEAYVTQQ-DKIRLVGELMTVIG
SAIILFLEIPDIFRVGFS--RYFGQTVLGGPFHVI------------TITYSFLVLVTMV
MRLTNTSGEVVPMSFALVLGWCSVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLLRFCWLMAVVIVGFASGGAAFYIIFQTED------------
----PSA------------------LGEFYD------YPMALFSTFELFLTIIDGP----
---ANYDVDLPFMYSIVYFAFAIIATLLMINLLVAM-MGDTHWRVAHEQDELWRAQVVAT
TVMLERKM--------PR-----------TLWPR-SGICGYKYGLG--------------
----------------DRWFL-----RVETNQDQNTLRARRYVEAFKGSD----------
------------------KE--E--------GQGHP-PEKRPSV----------------
------------------------------------TESGLLARASL--ALPTP------
------SLSRT---------TSRSSGSHRGWE-----------------IIRRNTL----
-GHVNLGL----------DLGEGDGDDRVYQL-------------------
>SHEEP15836_HOG_0033281_4a_Ovisaries
-------MGAPP--------------------SKARGLS-IQLQKLLTSWL-------VG
HQSALPTR-----------------------------------------------AP---
-----------QRALPP----------------------------------RSR------
IRES-----------------------------------------P----------L---
-----LRAAKDNDLCVLKKLLLD---------------------------------RNCD
FRQR------------------GA--VGETALHVAALY---DNLEAAMVLMEAAPE----
---------------------------------------LVKEPAICEPF----------
---------------------------VG--------------------------QTALH
IAVMNQNVNLVKALLAHGASVSA-RAIGSAFRLSPHN-LIYF-GEHPLSFAACMGSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILVLQPNKT---------------------
--------FACQ---------MYNLLLSYDRR-GDHLQSLDL------------------
------MLNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-YIQW------TCGPLTSTL-----YDLTEIDSWGE-----------------------
----------DVSFLELVVS-SKKRE----------------------------------
------------------------------------------------------------
------ARQILEQTPVKQLVNFKWRKYGRPYFCILGALYVLY------MICFTMCCIHRP
----LKAR-SD---NRT------DSR-DITVFQQKLLQEAYVTQQ-DKIRLVGELMTVLG
SAIILFLEIPDIFRVGFS--RYFGQTVLGGPFHVI------------TITYSFLVLVTMV
MRLTNTSGEVVPMSFALVLGWCSVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLLRFCWLMAVVIVGFAS---AFYIIFQTED------------
----PSA------------------LGEFYD------YPMALFSTFELFLTIIDGP----
---ANYDVDLPFMYSIVYFAFAIIATLLMINLLVAM-MGDTHWRVAHEQDELWRAQVVAT
TVMLERKM--------PR-----------TLWPR-SGICGYKYGLG--------------
----------------DRWFL-----RVETNQDQNTLRARRYVEAFKGSD----------
------------------KE--E--------GQGHP-PEKRPSV----------------
------------------------------------TESGLLARASL--APPTP------
------SLSRT---------TSRSSGSHRGWE-----------------IIRRNTL----
-GHVNLGL----------DLGEGDGEDRVYQL-------------------
>TURTR05382_HOG_0033281_4a_Tursiopstruncatus
-------MGPPP--------------------PKARGLW-IQLQKLLTSWL-------AG
QQD-WDQY-----------------------------------------------LD---
-----------EAYMLQ----------------------------------QKR------
IRES-----------------------------------------P----------L---
-----LRAAKDNDLCVLRELLLD---------------------------------RTCD
FRQR------------------GA--LGETALHVAALY---DNLEAAMVLMEAVPE----
---------------------------------------LVKEPTICEPF----------
---------------------------VG--------------------------QTALH
IAVMNQNVNLVKALLAHGASVSA-RAVGSAFCLSPHN-LLYF-GEHPLSFAACMGSEETV
RLLIE---HGADIRAQDSLGNT-----VLHILVLQPSKT---------------------
--------FACQ---------MYSLLLSYDGR-GDHLQSLDL------------------
------VPNHQGLTPFKLAGVEGNTT-----------MFQHLMQK--------------R
K-HIQW------MCGPLTSTL-----YDLTEIDSWGE-----------------------
----------DVSFLELVVS-SKKRE----------------------------------
------------------------------------------------------------
------ARQILEQTPVKQLVSFKWRKYGRPYFCIVGALYVLY------MICFTMCCIHRP
----LKPC-SG---NRT------NSR-DITILQQRLLQEAYVTQQ-DKIRLAGELMTVFR
AVIILFLKIPDIFRVGFS--PY-GQTVLGGPFHVI------------TITYASLVLVTMV
MRLSNTNGEVVPMSFALVLGWCSVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLLRFCWLMAVVIVGFAS---AFFIIFQTED------------
----PSN------------------LGQFYD------YPMALFSTFELFLTIIDGP----
---ANYDVNLPYMFSIIYFAFAIIATLLMLNLFVAM-MGDTHWRVAHEQDELWRAQVVAT
TVMLERKM--------PR-----------TLWPR-SGICGYKYGLG--------------
----------------DRWFL-----RVETNQDQNALRVRRYVEAFKGSD----------
------------------KE--E--------EHEHL-SEKQSSV----------------
------------------------------------VESGILARASL--ALPTP------
------SLSRT---------TSRNSSSHRGWE-----------------IIRRNTL----
-GHLNLGL----------DLGEGDGEESVYHI-------------------
>MYOLU08862_HOG_0033281_4a_Myotislucifugus
-------MGTPP--------------------PKVKGPW-THLQKLLTSWM-------FR
EKD-WDQQ-----------------------------------------------LD---
-----------EAHMLQ----------------------------------QKR------
IQES-----------------------------------------P----------L---
-----LQAAKDNDLSVLKKLLLD---------------------------------RSCD
LRQR------------------GA--LGETALHIAALY---DNLEAAMVLMEAAPE----
---------------------------------------LVYESTLCEPF----------
---------------------------VG--------------------------QTALH
MAIMNQNVNLVRALLAHGASVSA-RATGTAFRLSPHN-HIYF-GEHPLTFAACVGSEEIV
RLLIE---HGANIRAQDSLGNT-----VLHILVFQPNKT---------------------
--------FACQ---------MYNLLLSYDGH-GGHLQSLDL------------------
------IPNHQGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HIQW------SYGPLTSTL-----YDLTEIDSWGE-----------------------
----------KVSFLELVVS-SKKRE----------------------------------
------------------------------------------------------------
------ARQILEQTPVKQLVSFKWRKYGRPYFCILGALYVLY------MSCFTMCCVNRP
----LKNC-SS---NHT------DSR-DITLKEQKLLQEAYVTEQ-DKIRLVGELVTVVG
ALIMLILEIPDIFRVGAS--RYFGQTVLGGPFHVI------------IITSASLVLVTMV
MRLSNTRGEVVPMSLGLVLGWCSVIYFARGFQMLGPFSIMIQK-----------------
-------------MIFGDLLRFCWLMAVVILGFASGGAAFFIIFQTED------------
----PKK------------------LGEFYN------YPTSLFTTFELFLTLIDGP----
---ANYDVDLPFVYHITYAAFAIIATLLMLNLFIAM-MGDTHWRVAQERDELWRAQVVAT
TVMLERKM--------PR-----------FLWPR-SGICGYKYGLG--------------
----------------DRWFL-----RIESLHDQNPLRMLRYVEAFKSSD----------
------------------RE--D----------EHL-SEKHLSV----------------
------------------------------------VENGTRARGSL--TLPTP------
------SLSRT---------TSR-SSSHRGWE-----------------ILRRNTL----
-GHLNLGL----------ELGEGDGEENMYL--------------------
>PTEVA06098_HOG_0033281_4a_Pteropusvampyrus
-------MRAPS--------------------PKAKGLW-AQLQKLLTSWL-------FG
DKD-WEQR-----------------------------------------------LD---
-----------EAHMLQ----------------------------------QKR------
IRES-----------------------------------------P----------L---
-----LWAAKGNDLCLLKKILLE---------------------------------QTSD
FQQR------------------GA--LGETALHVAALY---DNLEAAMVLMEAAPE----
---------------------------------------LV-------------------
------------------------------------------------------------
-------------------------------------------XEHPLSFAACVGSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHVLVFQPNRT---------------------
--------FACQ---------MYNLLLSYDRR-GDHPQSLDL------------------
------VPNRQGLTPFKLAGVEGNAV-----------MFQHLMQK--------------R
K-HIQW------TCGPLTSTL-----YDLTEIDSWGE-----------------------
----------KVSFLELVVS-SKKRE----------------------------------
------------------------------------------------------------
------ARQILEQTPVKQLVSFKWRKYGRPYFCVLGALYVLY------MSCFTMCCVYRP
----LKFR-SG---NRT------DSR-DITLLEQKLLQEAYVMEQ-DKIRLVGELVTVIG
AVIMLLLEIPDIFRVGAS--RYFGQTVLGGPFHVI------------IITYASLVL----
-------AEVVPMSLALVLGWCSVMYFARGFQMLGPFSIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFFIVFQTED------------
----PEK------------------LGEFYD------YPTALFSTFELFLTIIDGP----
---ANYDVDLPFMYSITYAAFAIIATLLMLNLFIAM-MGDTHWRVAQERDELWRAQVVAT
TVMLERKM--------PR-----------FLWPR-SGICGRKYGLG--------------
----------------DRWFL-----RIEH-QDQNPLRVLRYVEAFKSSD----------
------------------KE--D--------GPEHL-SEKRPSV----------------
------------------------------------FESGAAARASL--GSPTP------
------SLSRT---------TSRSSSSHRGWE-----------------VLRRNTL----
MGHLNLGL----------DLGEGDGEENVYL--------------------
>CAVPO13923_HOG_0033281_3a_Caviaporcellus
-------MG-------------------------AKGPW-IQFQKLLSSWL-------VR
EQD-SDQQ-----------------------------------------------LD---
-----------EAYMLQ----------------------------------QKR------
ILES-----------------------------------------P----------L---
-----LQAAKENDLCTLKRLLQD---------------------------------QRCD
FRQK------------------GA--LGEMALHVAALY---DNLEAATLLMEAAPS----
---------------------------------------LVMEPTLCEPF----------
---------------------------VG--------------------------QTALH
IAVMNQNVNLVRALLSHGASVSA-RATGLAFQHNPHN-LIYY-GEHPLSFAACVGSEEIV
RLLIE---HGADIRAQDSLGNT-----VLHILILQPNKT---------------------
--------FACQ---------MYNLLLSYDG--GDHLQSLEL------------------
------IPNYQGLTPFKMAGVEGNTV-----------MFQHLMQK--------------R
K-RIQW------SCGPLTSTL-----YDLTEIDSWGE-----------------------
----------ELSFLELVVS-SKKRE----------------------------------
------------------------------------------------------------
------ARQILEQTPVKELVNLKWRKYGRPYFCILGTLYILY------MICFTMCCVYRP
----LKFR-AD---NRT------HSR-DNTILQQKLLQEAYVTYQ-DYIRLSGELVSVTG
AVIILLVEIPDILRVGAS--RYFGQTVLGGPFHVI------------IISYASLVLVTMA
MRLTNVQGEVVPLSFALVLGWCSVMYFARGLQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMATVILGFAS---AFFIIFQTED------------
----PSS------------------LGEFSN------YPTALFSTFELFLTIIDGP----
---ANYSVDLPFMYSITYATFAIIATLLMLNLFIAM-MGDTHWRVAQERDELWRAQVVAT
TVLLERKM--------PR-----------FLWPR-SGICGCDYGLG--------------
----------------DRWFL-----RVETHHDQNPLRVLRYVEAFKNSD----------
------------------KE--E--------EQEQL-SEKQLSA----------------
------------------------------------NGSEALRRPSL--APQAS------
------SLSRN---------TSHSSSSHWGWE-----------------IVRRNIL----
-SKKILAC----------LLQALEGSK-LWDLS-----------------D
>ELEPHANT_TRPV5_XM_003422824
------------------------------------------------------------
-------------------------------------------------------ME---
-----------EAHMQQ----------------------------------QKR------
IRES-----------------------------------------L----------L---
-----LRAAKENDLCALKELLLD---------------------------------GACD
IRQR------------------GA--LGETALHVAALY---DNLDAALLLLEAAPE----
---------------------------------------LVREPMVSELYEV--------
--------------------------RLG--------------------------QTALH
IAVVNQNVNLARALLAHGASVSA-RATGVAFHRSSRN-LIYF-GEHPLSFAACVGSEELV
RLLIE---HGADIRAQDALGNT-----VLHILTLQPNKT---------------------
--------FACQ---------MYNLLLSFDGRGGDPLQSLDL------------------
------VPNHQGLTPFKLAGVEGNTV-----------MFQHLMQR--------------R
K-HIQW------TYGPLTSTL-----YDLTEIDSWGE-----------------------
----------ELSFLELVVS-SKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVSLKWKRFGRPYFYVLGAIYLLY------IICFTMCCIYRP
----LKSR-GG---NHT------HSR-DITIFQQKPLQEAYITYQ-DNVRLVGELVTIFG
AVIILLLEIPDIFRVGAT--RYFGQTILGGPFHVI------------IITYACMVLVTMV
LRLTNVNGEVVPMSVALVLGWCSLMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------
>PROCA04798_HOG_0033281_2b_Procaviacapensis
-------MGLPT--------------------PKTKGLW-VQLQTLLNSWL-------IR
EGD-WDQR-----------------------------------------------AD---
-------------HMLQ----------------------------------QKR------
IRES-----------------------------------------P----------L---
-----LRAAKDNDLCALRELLLG---------------------------------GTCD
IHQR------------------GG--LGETALHVAALY---DNLEAALLLMEVAPE----
---------------------------------------LVREPMVSELY----------
---------------------------EG--------------------------QTSLH
IAVMNQNVNLVRALLTHGASVSA-RATGVAFRHSPHN-LIYF-GEHPLSFAACVGSEELV
RL----------------------------------------------------------
------------------------------------------------------------
-------------------------X-----------MFQHMMQR--------------R
K-HIQW------TYGPLTSTL-----YDLTEIDSWGE-----------------------
----------ELSFLELVVS-SKKRE----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVSLKWKRFGRPYFYLLGAIYLFY------IVCFTMCCVYRP
----LKSC-GG---NHT------SSR-DITIFQQKPLEEAYMTYQ-DSIRLVGELVSIFG
AVIILVVEIPDIFRVGAT--RYFGQTILGGPFHVI------------IVTYACMVLVTMV
MRLTSVDGEVVPMSFALVLGWCSIMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTED------------
----PTN------------------LGEFYN------YPMSLISTFELFLTVIDGP----
---ANYDVDLPFMFSVVYCAFAIIATLSMLNFI--M-MGDTH-RVVHEQDEL-RAQ----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------
>MONDO14722_HOG_0033281_6b_Monodelphisdomestica
-------MECPP--------------------LKWRGTW-TYLRELLCTGI-------PK
EKL-WSQR-----------------------------------------------LD---
-----------EANMLQ----------------------------------QKR------
IWES-----------------------------------------P----------L---
-----LKAVKENDLCTLKKLLLD---------------------------------GPSE
IHQR------------------GA--LGETALHIAAFY---DNLEAAKLLMDVAPE----
---------------------------------------LVNETMTSELY----------
---------------------------AG--------------------------QSALH
IAIVNQNTNLVRALLARGASVSA-RATGMAFRQN--K-LYYF-GEHPLSFAACMGNEEIV
RLLIE---YGADIRAQDYLGNT-----VLHILILQSSKT---------------------
--------FACQ---------MYNVILSYDGR-GSHLQPLEL------------------
------ISNHEGLTPFKLAGVEGNTV-----------MFQHLMQK--------------R
K-HIQW------TYGPLTSTL-----YDLTDIDSCGD-----------------------
----------ELSFLELVVY-TKKRQ----------------------------------
------------------------------------------------------------
------ARQILDQTPVKELVSLKWKMFGRQYFYMLGALYILY------IICFTTSCVYRP
----LKPR-SS---NLT------NPR-DITLLQQKCLQESYVTYE-DHIRLVGELVSVAG
AVIILLIEIPDILRIGAA--RYFGHTILGGPFHVI------------VITHACMVLLIMV
MRLTSTSGEVVPMSFALVLGWCNVMYFTRGFQMLGPFTIMIQK-----------------
-------------MFFGDLLRFCWLMAVVILGFAS---AFYVIFQTEN------------
----PDR------------------LGHFFN------YPMSVFTTFELFLTVIDGP----
---ANYDVDLPFMYCLVYFAFAIIAVLLMLNLFIAM-MGDTHWRVAHERDELWRAQVVAT
TVMLERKL--------PR-----------CLWPR-SGICGKEYGLG--------------
----------------DRWFL-----RVEDLQDHNPLRVLRYVEALKPSD----------
-----------------QNE--S--------EQEHL-SEKLPSR----------------
------------------------------------QKGTILGKASL--LTPTT------
------SLSRT---------TSQSSSNHWGWE-----------------VLRRNTL----
-GHVNHGL----------DLRDGDEEEKVYHL-------------------
>ERIEU10782_HOG_0033281_4a_Erinaceuseuropaeus
-------MGALP--------------------PRAKGPW-AQLQRLLRTWL-------AR
EQD-WDQR-----------------------------------------------LD---
-----------EAHMLQ----------------------------------QKR------
IREC-----------------------------------------P----------L---
-----LRAAKENDLCVLKKLLLD---------------------------------RTCD
FRQR------------------GA--LGETALHIAALY---DNLEAAMVLMEATPE----
---------------------------------------LVKEATL--------------
------------------------------------------------------------
-------------------------------------------GE---PF----------
-LXLR-------------------------------------------------------
--------------------------------------SLDQ------------------
------MPNLQGLIPFKLAGVEGNTV----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----XARQILEQTPVKQLVSFKWKKYGRPYFCILGALYVLY------MICFTMCCVYRP
----LKFR-TS---NRT------NSR-DNTIFQQKLLQXI--------------------
----------SIFWVGAS--HYF---VLLLPVYLIN-----------IITYAFLVLVTMV
MRLSSIDGEVVPISIALVLGWCSVMYFARGFQMLGPFTIMIQK-----------------
-------------MIFGDLMRFCWLMAVVILGFAS---AFYIIFQTEN------------
----PTN------------------LGHFYD------FPMALFSTFELFLTIIDGP----
---ANYDVNLPFMYGIVYFAFAIIATLLMLNLFIAM-MGDTHWRVAHEQDELWRAQVVAT
TVMLERKL--------PR-----------FLWPR-SGICGCEYGLG--------------
----------------DRWFL-----RVENHHDQNSLRVLRYVEAFKSSD----------
------------------KE--D--------GQGHP-SEKQPFG----------------
------------------------------------IESGSLVRIPT--ALPTP------
------SLSRA---------TSRSSSH-RGWE-----------------ILRRNTL----
-EFTNLGL----------DLGEEDGEE-NYHI-------------------
>Nanorana_parkeri_XP_018409300.1
-------MGIFQC-------------------NKTSGIP-SNVWNGIKSQI-------QS
HAP------------------------------------------------EGLELD---
-----------VVHMLQ----------------------------------QKR------
IREC-----------------------------------------P----------L---
-----LNAARENDVGAIRKLLDC---------------------------------ATTE
LYVR------------------GA--VGETALHVAALY---DNLEAAKLLLEAAPD----
---------------------------------------LVNQTVTSTLY----------
---------------------------EG--------------------------QTALH
IAAVNQNVNLVELLIQKGADLYSPRAIGTFFSYSQDN-LFYF-GEHVLSFAACVGSEAVV
RLLIE---NGANIRAQDSYGNT-----VLHILTLQPNQV---------------------
--------ISCM---------IYDLILSYDD--KRNNVDLQM------------------
------IPNFMGLTPFKLSASEGNVE-----------MFQHLLKK--------------R
K-QIQW------SFGPINSVL-----YDLSGIDSRDE-----------------------
----------HQSVLELVVS-SRKRE----------------------------------
------------------------------------------------------------
------ARHILEMTPVKELVCLKWRSCGRPYFWLLAAIYFLY------MVCVTVCCTYRP
----LKSI-P----KSN------DTR-DAVVMIQQSLSEAYVTYQ-DQLRLGGELISVIG
ALVILLLLIPDLLRVGAT--RYFGQTVLGGPFHVI------------IITFACMVMAVLV
MRVTNSSGEVVPMSLALVLGWCYILYFTRGFQMLGPFTIMIQK-----------------
-------------MIFGDLLRFCWLMVVVILGFGG---AFYVIFQTQD------------
----SGD------------------LGQFMT------YPMSLFSTFELFLTIIDGP----
---ANYEVDLPFMFSVVYSAFAIVAALLMLNLLIAM-MGDTHWRVSHEGDELWRAQVVAT
TLMLERKM--------PK-----------VLWPR--------------------------
---------------------------VEERKDLKAEKLKKIVNAFKIDDDK--------
------------------KD--D----V---------EENQSLKVDL-------------
------------------------------------SDEKIISKRVS--MSETP------
------VLLRK---------LSQRSSN-RGWN-----------------ILRKASI-DQL
QGKVNYAL----------DL-----DEHIYDV-------------------
>Xenopus_laevis_XP_018080421.1
-------MGLFYC-------------------HKNSSVT-NNVWNGLKSQI---------
----WNRAP------------------------------------------QGLELD---
-----------EIHMLQ----------------------------------QKR------
IQES-----------------------------------------P----------L---
-----LLAAKENNVGMMKKLLDC---------------------------------PSTD
LYSR------------------GA--MGETALHVAALY---DNLEAAQMLINKAPN----
---------------------------------------LVNLPCTSALY----------
---------------------------EG--------------------------QTALH
IAAVNQNQNLVKLLILNGADVRSPRVTGSFFAFNQRN-LFYF-GEHVLSFAACVGHEGIV
RLLIE---SGANIRAQDCYGNT-----VLHILALQPNRT---------------------
--------FSCQ---------MFDLIVSYDK--GERGVRLEN------------------
------IPNNRGLTSLHVAAAEGNTV-----------MFQHLVQR--------------K
K-QIQW------TFGPLNSTL-----YDLSGIDSWGE-----------------------
----------DQSVLELVVA-SKKKE----------------------------------
------------------------------------------------------------
------ARHILDLTPVKQLVFLKWRSCGRPYFCLLASIYILY------IVTVTMCCIYRP
----LEPI-PGIGNQTT------VTR-NITKLMQKPFNEAYQTYE-DELRLVGELISVVG
AIIILLLLIPDMLRVGAT--RYFGQTVLGGPFHII------------IIIFAIMVLTTLV
MRLTSSDGEVVPMSLALVFGWCYVLYFTRGFQMLGPFTIMIQK-----------------
-------------MIFGDLLRFCWLMAVVILGFGG---AFYVIFQTED------------
----SSQ------------------LGHFMS------YPMSLFSTFELFLTIIDGP----
---ANYQVDLPFMYSVMYSAFAIIAALLMLNLLIAM-MGDTHWRVAHERDELWKAQVVAT
TIMLERKM--------PK-----------RLWPR-LGICGKDYGLG--------------
----------------ESWFL-----RVEERKDVDKKKIKPYVDAFQCAD----------
------------------ED--DSK------------REKEALKPSLS------------
------------------------------------EDKITILLPNKE-TPPSPSML---
------TLDPN---------TSHRRSN-RGWQ-----------------KIRKTPL-DQL
QGRTNYGL----------DI-----EDEIYEV-------------------
>XENTR18186_HOG_0033281_10a_Xenopustropicalis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------GEHILSFAACVGNAELV
RLLLS---HGADLEAKDSHGNT-----ILHILALQSNKM---------------------
--------AACQ---------MYDLIMSYQQ--DKESPGLEE------------------
------TCNNDGLTPFKMAAVEGNTV-----------LFQHLVQK--------------R
R-HVHW------TFGPITCYL-----YDLNEIDTWED-----------------------
----------AQSVLDLVVS-EKNKE----------------------------------
------------------------------------------------------------
------VNRLSLTEPDRLLAIINWHIIS-------GVQFALHSVNKWGAVCLTQCRIIEL
----KQLE-YR---GKS------DPR-TLTIRISAP-QESYLTYD-DHVRLAGEMISVSG
AIVILLLKVPDLLQIRSV--RSLTQAVHGGPFTLI------------IVVFPCLVLVVFI
MRLTNTDGEVIPMSMALVLGWCYVMYFARGFQMLGPFTIMINK-----------------
-------------VSF--LERLGFLLGLYAMGLNT--AAFYTIFQTVD------------
----QTQ------------------FGYFYS------YLMSLFSTYELFLNVINSP----
---TNYDVDLPIIFFVVYVIFTIIANLLMLNILIAM-MGDTYWRVAQERDELWRAQVAAT
TVMLEKKL--------PL-----------CLWPR-TGVCGTEYGLR--------------
----------------NHWYL-----RVISRKDPSQQKIQRYIEAFQGPEED--------
------------------NE--E--------KQREK-SVKSSEER---------------
------------------------------------------------------------
------TSERA------KAQYLPRPTSGRGWQ-----------------ILRSITT-ERL
RGLL---L----------QSSSQEAEVEVHHV-------------------
>Xenopus_laevis_XP_018080408.1
----------------------------------------MVPWQR------------QK
QEN---------------------------------------------------CAC---
-----------QTSLLQ----------------------------------QKR------
IREL-----------------------------------------P----------I---
-----LYAAQLNRVKTLGKLLKL---------------------------------KSTD
ALTR------------------GA--AGETALHVAVLY---DNVEAVRVLLEKAPE----
---------------------------------------LVNEPMTSDLY----------
---------------------------KG--------------------------QTALH
IAVMRQNMVIVQDLIAKGADVSTPQAVGSFFQLNPSN-TFYY-GEHILSFAASVGNADLV
RLLLQ---HGADLEARDSRGNT-----ILHILALQPNKM---------------------
--------SACQ---------MYDLILSNHQ--EKEGPGLEE------------------
------TCNNDGFTPLKMAAMEGNTV-----------LFQHLVQK--------------R
R-HVHW------TFGPVTCYL-----YDLKEIDTWED-----------------------
----------PQSVLDLVVS-GKKKE----------------------------------
------------------------------------------------------------
------ARRILDISPVKELVNRKWQRFGRPYFWLLAVVYVLY------MTCVSLCCVNRP
----LKPR-PD---NAT------NPR-DITLLVQKSLQEAYNTYD-DHVRLAGEMISVSG
AIIILLIKVRDLLQIRSV--RALTQAVHGGPFTII------------IVLFPCLVLVTFI
LRLTNTDGEVIPMSMALVLGWCYVMYFTRGFQMLGPFTIMIHK-----------------
-------------MIFGDLLRFCWLMVVVIFGFAT---AFYIIFQTED------------
----PSQ------------------LGHFYN------YFMSLFSTFELFLNVINSP----
---TNYDVDLPLIFFFVYFIFTIIANLLMLNLLIAM-MGDTHWRVAQERDDLWRAQVAAT
TVMLERKL--------PL-----------CLWPR-SGVCGTEYGLR--------------
----------------NHWYL-----RVICRKDLSQQKIQRYIKAFQGPEGD--------
------------------NE--E--------KQRQK-PEKSSEQSTFEIDIRCRQTDNSA
EQSLEDKSETKLSSNKTEGTCLRLPEIEITECFGPSHTQSRLTKEDTNSGLNKPQMESLE
LPQICISAERADLASLEKVQYTQRPMSGRGWQ-----------------ILRSVTI-EQL
RGIL---L----------QSGAEEAEEEVHHV-------------------
>Nanorana_parkeri_XP_018409298.1
----------------------------------------MVLWRK------------EK
QEE---------------------------------------------------SAC---
-----------EINLLQ----------------------------------QKR------
IQEL-----------------------------------------P----------L---
-----LRYVQGNHTNALRKLLAL---------------------------------KTTN
LLQR------------------GA--VGETALHLAVLH---DNLESVRILLERAPE----
---------------------------------------LVNQPMTSDLY----------
---------------------------KG--------------------------QTALH
IAVMRQNLAVAQELIRNGANVAMARAVGTYFQLKP-N-SFYY-GEHILSFAACVGNAELV
RLLLQ---HGADAEDKDSHGNT-----VLHILALQPNKM---------------------
--------SACQ---------IYDLILGYHK--EKFGPGLEE------------------
------INNDNGLTPLKMAALEGNTV-----------MFQHIVQK--------------R
R-QLQW------TFGPISCYL-----YDLTEIDTWGD-----------------------
----------PKSVLDLVVS-AKKRE----------------------------------
------------------------------------------------------------
------ARRILDLSPVNQLVNRKWQRFGRPYFWTLSALYVLY------MICVSLCCANRP
----LKPR-TD---NIT------NPR-DITILVQVPLGEAYLTSG-DHLRLAGEILSVIG
AIIILLFKIPDLFQIREP--KYLAQAVQGGPFTLI------------IILFPCLVLVTLI
LRMTNTDGEVVPMSILLVLGWCYVMYFARGFQMLGPFTIMIHK-----------------
-------------MIFGDLLRFCWLMVVVIFGFAT---AFYIIFQTED------------
----PSQ------------------LGHFYN------YLMSLFSTFELFLNVINSP----
---TNYAVDLPYIFHVVYFAFTIIANLLMLNLLIAM-MGDTHWRVAQDRDELWRAQVAAT
TVMLERKL--------PR-----------SLWPR-SGVCGTEYGLG--------------
----------------DHWYL-----RVVVRKDLSQQKIRRYVEAFQGPEENHHLDKHLS
NGLKLDQTLKPGLPKVMVTE-VDTH-----E------PPRTSHEALRT------------
-----------------------------------SQTANGLLHEDAARTQSAPHMTHLD
IPRVYMEPSSSGLQCLGREVPVVRKASGRGWK-----------------ILRSVPV-KRL
QGHT------------SQNIQGDDDEEEIHHV-------------------
>XENTR18187_HOG_0033281_10b_Xenopustropicalis
------------------------------------------------------------
------------------------------------------------------------
------------TFCLW----------------------------------EAN------
VHEM-----------------------------------------P----------L---
-----FLAAKENDVGRLQELLGS---------------------------------NQCY
SSQR------------------GA--LGETALHVAAGY---DNLRAAETLLTADPS----
---------------------------------------LVNVPMTSQLY----------
---------------------------QG--------------------------QTALH
IAAVNQNMNLVRILIDKGADVSSPRATGSFFSLKATN-LFYF-GEHILSFAASVGNADIV
KLLVE---KGADVRAQDSWGNT-----VLHILVLQPNKA---------------------
--------MACQ---------MFDLLTSLEC--GQRWPPLNQ------------------
------MVNHQGLTPLKLAAAEGNVM-----------MFQYLMQK--------------G
V-RKVP------SMGPLYYTL-----YDMTEIDSWGS-----------------------
----------PCSVLHLLVS-SRKSE----------------------------------
------------------------------------------------------------
------ARKILDVSPVKELVNEKWQSFGRPYFLLLGAIYVLY------MICVSLCCANRR
----LVPI-TG---NAT------NPR-DITLLKQAPLLESSLILW-IMVHMIGVIYQTLG
IIKILSCILP----------NVFDNMPQNRYYEILASHACISPPCFYRVLYSCMVLATLA
LRLTDSDGEIIPMSLALVFGWCYIMFFARGFQMTGPFTVMIHK-----------------
-------------IIFGDVLRFFWLMMVVILGFGT---ALFVVFQTED------------
----PTQ------------------MGVFYN------YPMSLYSTYQLLINVINSP----
---ANYAVNLPPMYSIVYFPFTLIANLMMMNMLIGM-MGDTHWRVAQERDELWRAQLAAI
TIMLEGKF--------PK-----------WFWPR-LGVCGSKYGLG--------------
----------------DRWYL-----CVKE--SQDPQKILFPPQKPQSPP----------
------------------QQ--Q--------------VSGKGKPSI--------------
------------------------------------TITDMGNNQQLN-GSGAP------
--------------------IAQRRSS-RGWQ-----------------ILRGATI-DQL
KG---------------TSVFKRESHQEVFYI-------------------
>Xenopus_laevis_NP_001082336.1
-------M----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------P----------L---
-----LLAAKENDVDHLRLLLAS---------------------------------DECY
PNQR------------------GA--SGETALHVAACY---DNLEAAEILLTADPS----
---------------------------------------LVNMPMTSQLY----------
---------------------------QG--------------------------QTALH
IAAVNQNMNLVKILIDRGADISSPRAPGSFFSLKAKN-LFYF-GEHILSFAASVGNSDIV
KLLVK---KGVDLCAQDTWGNT-----VLHILVLQPNKT---------------------
--------MACQ---------MFDLLMSLES--AQKWPPLNQ------------------
------IPNHDGLTPLKLAALEGNIT-----------MFQYLMQK--------------G
V-HKVP------SLGPISYTL-----YDMTEIDSWGS-----------------------
----------PCSVLHLLVS-SRKSE----------------------------------
------------------------------------------------------------
------ARKILDISPVKELVNEKWQNFGRPYFLILGAIYVLY------MICVSLCCANRR
----LRPL-WK---NST------NPR-DITVLTEAPLLESYNYPM-DELHLVGELITIIG
ALAMLLLEIPVLMSAQRI--SFFKDPVSGGPFHLI------------LVLYSCMVLACLA
LRLTDSDGEIIPMSLALVLGWCYTMYFARGFQMLGPFTVMIHK-----------------
-------------IMFGDLLRFFWLMMVVIIGFGT---ALFVIFQTED------------
----PSQ------------------MGIFYS------YPMSLYSTYQLFINVINSP----
---ANYDVDFPPMFSVIYFPFTLISNLLMLNLLIAM-MADTHWRVAQERDELWRAQLAAI
TVMLEGKF--------PK-----------WFWPR-LGICGSKYGLG--------------
----------------DRWYL-----CVKE--TQDPQKIIFPPKKNPSPN----------
------------------AQ--Q--------------LSESGNPSI--------------
------------------------------------TITVIGDSQELE-GSRAP------
--------------------MAQRRSS-RGWQ-----------------ILRHATI-DQL
LG---------------TSLLKRESQQEIFYI-------------------
>Nanorana_parkeri_XP_018409335.1
-------M--------------------------------------------------EE
EAS----------------------------------------------------MD---
--------------LLQ----------------------------------QRR------
IQEM-----------------------------------------P----------I---
-----LQAAKENNVELLREILAS---------------------------------EKCD
PFQR------------------GA--LGETALHMAALY---DNLEAAEILLTEAPY----
---------------------------------------LLNLPMTSELY----------
---------------------------QG--------------------------QTSLH
IATVNQNMNLVKMLIQRGADVSSPRATGSFFIQRPKI-LFYF-GEHILSFAACVGNADIV
KLLVE---NGANLRAQDCWGNT-----VLHILILQHNKT---------------------
--------LSCQ---------MYDLLLSLNN--EQSGPSLDM------------------
------ILNNQGLTPLKMAAAEGNVT-----------MFQHLLKK--------------G
V-RTFQ------SMGPTSYML-----YDLTEIDSWGS-----------------------
----------SGSVLHLLVT-SKKAE----------------------------------
------------------------------------------------------------
------ARRILDISPVKDLLNEKWQRFGRPYFWTLAAVYVLY------MICVSLCCANRP
----LKPL-QN---RSS------NPR-DTTILKQTNLLESNNTTM-DELRLVGELISVIG
ALAMLLLEIPVLMSTRSI--ALLQDTVSGGLFHFI------------LVLFSCSVLLTLA
LRLTNSDGEVIPMSLALVFGWCFAMYFARGFQMLGPFTVMIHK-----------------
-------------IIFGDLLRFFWLMMVVIIGFGT---ALYVVFQTED------------
----PNA------------------MGIFYS------YAMSIYSTYQLFINVINSP----
---ANYTVDLPVMYGVVYFPFTLISNLLMLNLLIAM-MGDTHWRVAQERDELWRAQLAAT
TVMLESKL--------PL-----------YFLPR-LGVCGAEYGLG--------------
----------------NHWYL-----CVKKDIQEDQNLVTLPTQSYIYPE----------
------------------TQ--A--------------MRKNSTSS---------------
------------------------------------------SNKDSE-GDQDP------
--------------------QSKRRSS-RGWQ-----------------ILRRATI-DEL
QR---------------SSILSKHSEPEVYYI-------------------
>Zebrafish_TRPV6
-------MPPAIS--------------------GEINHW----WRQMRFRL-------QH
KKG-WNEM-----------------------------------------------LD---
-----------ETFLMQ----------------------------------TKR------
VNDI-----------------------------------------P----------L---
-----FSATKENNAACIKKLLDC---------------------------------SSTD
IFER------------------GE--LGETALHVAVMN---DNFEAAVALMNGAPE----
---------------------------------------LINEPMTSELY----------
---------------------------HG--------------------------LTALH
IAVINQNPNLIWEMIKRGADVTTPRVTGMYFRKRREG-LFYY-GEHILAFAACVGNKDIM
SMLIK---AGANIRAQDSRGNT-----ILHLLVLQPNKT---------------------
--------TACQ---------IFDFLLAQDAE-QDSALPLDM------------------
------VPNYKGLTPFKLAARDGNVV-----------VFQHLVNR--------------R
K-VVQW------SLGPVSSYL-----YDLTEIDSRVD-----------------------
----------EHSVLEIIAT-SHKKE----------------------------------
------------------------------------------------------------
------ARRILELTPVRQLITLKWNLYGKHYFRSLMVIYLVY------ISIFTVCCINRP
----LKGI-PE---NYT------KAGNDHTIKIKKTFKESYQSYT-DQLRLIAEIISLIG
AIIILLIEIPGILAVGVK--RFFGQTALGGLFHVT------------LISYALLVLLLCG
LRVTGIQGELIPMAFSLILGWFSLVYFARGFEMLGPYVIVIQK-----------------
-------------SIFGDITKFMWLSIIFLIGSSA---ALWIFYMTQE------------
----PLA------------------LPQYRS------FPITLFSQFEVSVGQIDLP----
---VDHTLFTHPVVYWTHVCFSLISNVLLFNLLVAM-MSDTQWRVTQERDELWRTQVVAT
TLMLERKL--------PQ-----------CLWPR-LGVCGLMFGLG--------------
----------------ERWYL-----RVEDRNDIMAQKLKRYVDAFSKDVEA--------
-----------------PKE-EK--------------PSKSDGEQ---------------
------------------------------------------------------------
------SIAESN--------KEKSKKSKQYWS-----------------LIRRSIE----
-------C----------EKEECVDCPNFKFL-------------------
>Sinocyclocheilus_rhinocerous_XP_016413327.1
-------MSPAISRT----------------AAGEINHW----WSQLKFRL-------QH
RKG-WNEM-----------------------------------------------LD---
-----------ETFLMQ----------------------------------NKK------
VNDI-----------------------------------------P----------L---
-----FSATKENNAACIKKLLDC---------------------------------SSTN
IFER------------------GE--LGETALHVAAMN---DNFDAAVALMDGAPE----
---------------------------------------LINEPMTSELY----------
---------------------------HG--------------------------LTALH
IAAVNQNVNLVRELITRGGDVATPRVTGMYFRKRRGG-LLYF-GEHILAFASCVGNEEII
TMLIK---AGANIRAQDSLGNT-----ILHLLILQPNKT---------------------
--------TACQ---------IFDVLMSQDAD-LDPAIPLDM------------------
------VPNYRGLTPLKLAAKEGNLV-----------AFQHLANR--------------R
R-IIQW------SLGPLSSNL-----YDLTEVDSRED-----------------------
----------DLSVLEIIVS-SQKRE----------------------------------
------------------------------------------------------------
------ARRILELTPVRQLVRLKWNLYGKHYFRLLMLVYLLY------ISIFTLCCINRP
----LKDI-PE---NYT------KADNDQTIKVQKSFTESYQTYK-DHLRLIGEIISVIG
AIVILLIEVPSILRVGAK--RYFGQSALGGPFHIT------------LIGYASLVVILCV
LRTTGMAEELVPMAWALVLGWSNVMYFARGFEMLGPYVIVIQK-----------------
-------------TIFGDMTKFMWLSLIFLTGSSA---GLWVYYITQD------------
----PSA------------------LPPYRS------FPITIFTQFELSIGLIDLP----
---VDHMLYTHPVVHSVHIYFSVVAYILLFNLLIAM-MSDTQWRVTQERDELWRTQVVAT
TLMLERKL--------PL-----------RLWPR-LGICGLAFGLG--------------
----------------ERWYL-----RVEDRNDPLVQKMKRYINAFSKDGEP--------
-----------------AKEREE--------------TGKNDPGND--------------
------------------------------------------------------------
------PLQTNFIV---KKRPRIQRRPIKCWQ-----------------LIRQSIE----
-------C----------EKEENVDCPDIKYI-------------------
>TETNG13092_HOG_0033281_1a_Tetraodonnigroviridis
-------MSPSLARS----------------APSELNHW----WSQLRFRL-------QN
KKG-WNEM-----------------------------------------------LD---
-----------ETFLLY----------------------------------TKH------
INNI-----------------------------------------P----------L---
-----FYAAQKNNAGCIKKLLGC---------------------------------SSTN
IFER------------------GA--LGETALHIAVMN---DSLDAAVALMDGAPE----
---------------------------------------LINEPMTSELF----------
---------------------------QG--------------------------LTPLH
IAVVNQNINLVQHLISRGGDVATPQVSGLYFRKRIGG-LIYY-GEHVLSFAACTGNEDII
SMIIN---AGASTRVQDYRGNT-----VLHILILQPNKT---------------------
--------IACQ---------AIDLIMARDAE-LDQAVPLDM------------------
------VPNSRGLTPFKLAAKEGNSV-----------AFQHLVNK--------------R
R-LVQW------SLGPLTSYL-----YDLTEIDSWAD-----------------------
----------NMSVLEIIVA-SQQKE----------------------------------
------------------------------------------------------------
------ARGILELTPVRQLVSLKWNLYGKHYFRLLLFLYLLY------IGTFTLCCIFRP
----LKDI-SE---NYT------RTDMDQTIRIQKTLQENYVTYG-DRLRLVGEVISVLG
ALVILVLEIPDIIRVGAK--RYFGQTALGGPFHVI------------LISYACLVVLLCV
FRACEVHGETVLMALCLVLGWCNVMFFARGFEMLGPYVIMIQK-----------------
-------------IIFGDLTKFMWLSFIVLIGSST---ALWVVYMTQD------------
----PNA------------------LPAYRS------FPITLFSQFELSVGLIDLP----
---VDHTITTPPIIHVLHFTFSMVSCILLLNLLIAM-MSDTHWRVAQERDELWRIQVVAT
TLMLERRL--------PR-----------CLWPR-LGVCGLEYGLK--------------
----------------ERWYL-----RVEDRNDPMFQKMRRYIKAFSKEDET--------
-------------------E------------------AKTDTAKGL-------------
-------------------------------------------------KPTLPLPG---
------LSATEE---------FPNRKSLTGWQ-----------------MIRHSAL----
-GLE---F----------GQEEKGDDQDIKFV-------------------
>TAKRU07416_HOG_0033281_1b_Takifugurubripes
-------MSPSLARS----------------APSELNHW----WTQLRFRL-------QN
KKG-WNEM-----------------------------------------------LD---
-----------ETFLLY----------------------------------TKH------
INNI-----------------------------------------P----------L---
-----FYAAQKNNAGCIMKLLGC---------------------------------SSTN
IFER------------------GA--LGETALHVAVMN---DNLDAAVVLMEGAPE----
---------------------------------------LINEPMTSELF----------
---------------------------QG--------------------------VTPLH
IAVVNQNINLVQHLISRGGDAATPRVTGLYFRKRIGG-LIYY-GEHILSFAACAGNEDII
SLIID---AGASTRVQDYRGNT-----VLHVLVLQPNKT---------------------
--------IACQ---------AMDLIMARDAE-LDQSVPLDM------------------
------VPNSRGLTPFKLAAKEGNRV-----------AFQHLVNK--------------R
R-VVQW------SLGPLTSYL-----YDLTEIDSWAD-----------------------
----------GMSVLELIVA-SQQKE----------------------------------
------------------------------------------------------------
------ARGILELTPVMQLVSLKWNLYGKHYFRLLLLLYLLY------IGTFTLCCTYRP
----LKDI-SE---NYT------KSELDHTIRVQKTLQESYVTRE-DSLRLVGEVISVLG
ALVILLLEIPDIIRVGAK--RYFGQTALGGPFHVI------------LISYASLVVLLCV
FRACEVQGEAVVMALSLVLGWSNVMFFARGFEMLGPYVIMIQK-----------------
-------------IIFGDLTKFMWLSFIVLIGYST---ALWVVYMTQD------------
----PDS------------------MPSFRS------FPITLFSEFELSVGLIDLP----
---VDHRIMTPPIVHVLHCTFSLVSYILLLNLLIAM-MSDTHWRVAQERDELWRIQVVAT
TLMLERRL--------PR-----------CLWPR-LGVCGLEYGLK--------------
----------------ERWYL-----RVEDRNDPLFQKMRRYIKAFSKEDDT--------
-------------------------------------DAKTDTTKDF-------------
-------------------------------------------------IPEPTQFG---
------LKTTES----------LNRKSLTGWQ-----------------MIRHSTL----
-GLE---L----------GQEEPEQDQDIKYL-------------------
>GASAC13598_HOG_0033281_Gasterosteusaculeatus
-------MSPSLARS----------------APSELNHW----WTQLRFRL-------QN
KKG-WNQM-----------------------------------------------LD---
-----------ETFLLH----------------------------------TKY------
INDI-----------------------------------------P----------L---
-----FYAAKKNSVGCIKKLLSC---------------------------------ASTN
IFER------------------GA--LGETALHVAVMT---DNLEAAVALMDGAPE----
---------------------------------------LINEPMTSELF----------
---------------------------QG--------------------------VTPLH
IAVVNQNINLVHHLITRGGDVATPRVTGLYFRKRIGG-LVYYEGEHILSFAACAGNEDII
SMVID---AGASTRVQDYRGNT-----VLHILVLQPNKT---------------------
--------IACQ---------AIDLIMARDVE-LDQSVPLDM------------------
------VPNYRGLTPFKLAAKEGNVV-----------AFQHLVNK--------------R
R-VVQW------SLGPLTSNL-----YDLTEIDSWAD-----------------------
----------NQSVLELIVC-GHRKE----------------------------------
------------------------------------------------------------
------ARKILELTPVRQLVSLKWNLYGKHYFRLLLLLYLLY------IGTFTLCCQYRP
----LKDA-PE---NYT------QSDIDKTIRVQKTLKESYVTHE-DNLRLVGEIISILG
AFAILLLEIPDILRVGAK--RYFGQTALGGPFHFI------------LISYACLVVLLFV
FRVCEVQGETVVMAVCLLLGWCNVMFFARGFEMLGPYVIMIQK-----------------
-------------VIFGDLTKFMWLSFIVLIGFST---SLWTVYMTQE------------
----VDS------------------IPAYRS------FPIALFSLFQLSVGLIDMP----
---VDQTIITPPIVYVLHCTFSLVSYLLLLNLLIAM-MSDTHWRVAQERDELWRTQVVAT
TLMLERRL--------PR-----------CLWPR-LGVCGLSYGLM--------------
----------------ERWYL-----RVEDRNDQMLQKMRRYVKAFSKEEEK--------
-------------------E-----------G-----LEKTDTTKGY-------------
-------------------------------------------------SSESPKLR---
------RK--------------NSTRSHAGWQ-----------------VIRDSAI----
-GLE---M----------QPLELGKDQCIKYN-------------------
>Larimichthys_crocea_XP_010741749.1
-------MSPSLARS----------------APSELNHW----WSQLRFRL-------QN
KKG-WNEM-----------------------------------------------LD---
-----------ETFLLY----------------------------------TKH------
INDI-----------------------------------------P----------L---
-----FYAAKKNSVGCIKKLLSC---------------------------------ASTN
IFER------------------GS--LGETALHVAVMN---DNLEAAVALMDGAPE----
---------------------------------------LINEPMTSDLF----------
---------------------------QG--------------------------VTPLH
IAVVNQNINLVHHLISRGGDVATPRVTGLYFRKRIGG-LIYY-GEHILSFAACAGNEDII
SMVID---AGASTRVQDYRGNT-----VLHILVLQPNKT---------------------
--------IACQ---------AIDLIMARDAE-LDQSVPLDM------------------
------VPNYRGLTPFKLAAKEGNIV-----------AFQHLVNK--------------R
R-LVQW------SLGPLTSNL-----YDLTEIDSWAD-----------------------
----------NMSVLELIVG-SHQRE----------------------------------
------------------------------------------------------------
------ARGILEVTPVRQLVSLKWNLYGKHYFRLLLLLYLLY------IGTFTLCCAYRP
----LKDA-PE---NYT------KSDMDKTIRVQKSLNESYVTHE-DNLRLAGEIISVLG
ALVILLLEIPDILRVGAK--RYFGQTALGGPFHVI------------LIGYACLVVLLCV
FRACEVQGEAVVMAVCLVLGWCNVMFFARGFEMLGPYVIMIQK-----------------
-------------IIFGDLTKFMWLSFIVLIGFST---SLWMVYMTQE------------
----PES------------------VPAYRS------FPITLFSQFELSVGLIDLP----
---VDHTIATPPIVHVLHCAFSVVSYILLLNLLIAM-MSDTHWRVAQERDELWRTQVVAT
TLMLERRL--------PR-----------CLWPR-LGVCGLNYGLR--------------
----------------ERWYL-----RVEDRNDPMLQKMRRYIKAFSKDDEK--------
-------------------E------------------EKTDTMKGS-------------
-------------------------------------------------MSGTPKLR---
------PKNRGG---------FNNRKSLTGWQ-----------------MIRHSAL----
-GLE---M---------GQDFELEDDQDIKYV-------------------
>Notothenia_coriiceps_XP_010786742.1
-------MSPSFARS----------------APSELNHW----WSQLRFRL-------QN
KKG-WNEM-----------------------------------------------LD---
-----------ETFMLH----------------------------------SKY------
INDI-----------------------------------------P----------L---
-----FYAAKKNSVGCIRKLLSC---------------------------------ASTN
IFER------------------GA--LGETALHVAVMS---DSLEAAVALMDGAPE----
---------------------------------------LINEPMTSELF----------
---------------------------QG--------------------------VTPLH
IAVVNQNINLVHHLITRGGDVATPRVTGLYFRKRIGG-LIYY-GEHILSFAACAGNEDII
SMLID---AGASTRVQDYRGNT-----VLHILVLQPNKT---------------------
--------IACQ---------AIELIMARDAE-LDQLLPLDM------------------
------VPNYRGLTPFKLAAREGNTV-----------AFQHLVNK--------------R
R-VVQW------SLGPLTSNL-----YDLSEIDSWAD-----------------------
----------NMSVLELIVG-SHQRE----------------------------------
------------------------------------------------------------
------GRRILELTPVRQLVSLKWNLYGKHYFRLLLLLYLLY------IGTFTLCCAYRP
----LKDA-PE---NYS------NSEMDKTIRVQKTLQESYVTHE-DNVRLAGEIISLLG
AFVILVLEIPDILRVGAK--RYFGQTALGGPFHVI------------LISYACLVVLLCV
FRACEVQGEDVVMSVCLVLGWSNVMFFARGFEMLGPYVIMIQK-----------------
-------------IIFGDLTKFMWLSFIVLIGFSS---SLWMVYMTQE------------
----PDS------------------IPSYRS------FPITLFSQFELSVGLIDLP----
---VDHTITTPPIVHVLHCTFSVVSYILLLNLLIAM-MSDTHWRVAQERDELWRTQVVAT
TLMLERKL--------PR-----------CLWPR-LGVCGLNYGLR--------------
----------------ECWYL-----RVEDRNDPMLQKMRRYVKAFSREEEN--------
-------------------E-KE--------G-----MEKTDTMKGS-------------
-------------------------------------------------ISGTPKLR---
------PKHRGG---------LNNRKSLTGWQ-----------------MIRHSTL----
-GLE---M----------ENEDSDEDQDIKYV-------------------
>Lates_calcarifer_XP_018538209.1
-------MSPSLARS----------------APSELNHW----WSQLRFRL-------QN
KKG-WNEM-----------------------------------------------LD---
-----------ETFLLH----------------------------------TKY------
INDI-----------------------------------------P----------L---
-----FYASKKNSADCIKKLLCS---------------------------------ASTN
IFER------------------GA--LGETALHIAVMN---DNLEAAVALMDGAPE----
---------------------------------------LINEPMTSELF----------
---------------------------QG--------------------------VTPLH
IAVVNQNTNLVYQLINRGGDVVTPRVTGLYFRKRIGG-LIYY-GEHILSFAACAGNEDII
SMVID---AGASTRVQDYRGNT-----VLHILVLQPNKM---------------------
--------IACQ---------AIDLIMARDAE-LDQSIPLDM------------------
------VPNYRGLTPFKLAAKEGNTV-----------AFQHLVNK--------------R
R-IVQW------SLGPLTSNL-----YDLTEIDSWAD-----------------------
----------DMSVLEIIVG-SHRRE----------------------------------
------------------------------------------------------------
------ARGILEVTPVRQLVSLKWNLYGKYYFRLLLFLYLLY------IGVFTLCCVFRP
----LKDA-PE---NYT------QSDMDKTIRVQKTLNESYMTYE-DNLRLAGEVISVLG
AFAILFLEIPDILRVGAR--RYFGQTALGGPFHVI------------LISYACLVVLLCV
FRACEVQGEAVVMAVCLVLGWCNVMFFARGFEMLGPYVIMIQK-----------------
-------------IIFGDLTKFMWLIVIVLIGFST---SLWMVYMTQA------------
----PDT------------------IPAYRS------FPISLFSQFELSVGLIDLP----
---VDHTVFTPPIVHVIHCAFSVVSYILLLNLLIAM-MSDTHWRVGQERDELWRTQVVAT
TLMLERRL--------PR-----------WLWPR-LGVCGLNYGLK--------------
----------------ECWYL-----RVEDRNDPMFQKMRRYIKAFTKEDEK--------
-------------------E-ME--------G-----LEKTDMIKGS-------------
-------------------------------------------------SSGTPKLR---
------PK--------------NNKKTLTGWQ-----------------MIRHSAL----
-GLE---M----------EQKEPEEDQDIKYV-------------------
>Cynoglossus_semilaevis_XP_016893333.1
-------MSPSLARS----------------APSELNHW----WSQLRFRL-------QN
KKG-WNEM-----------------------------------------------LD---
-----------EMFLLH----------------------------------TKY------
MNDI-----------------------------------------P----------L---
-----FYASKTNSTDCIRKLLSC---------------------------------SSTN
IFER------------------GA--LGETALHVAVMN---DSLEAAVALMDGAPE----
---------------------------------------LINEPMTSELF----------
---------------------------QG--------------------------VTPLH
IAVVNQNTNLVHHLICRGGDVVNPRVTGLYFRKRMGG-LLYY-GEHVLSFAACAGNEDII
SMVVE---AGASTRVQDDRGNT-----VLHILVLQPNKV---------------------
--------IACQ---------AIDLIMAHDAE-LDRPLPLDM------------------
------VPNFRGLTPFKLAAKEGNIV-----------VFQHLVNK--------------R
R-VVQW------SLGPLTSSL-----FDLTEIDSWAD-----------------------
----------DMSVLELIVG-SQQREVGHA------------------------------
-------------------------------------PAGAAQSETNSQLIHIS-----N
VFDVVKARRLLEVTPVRQLVSLKWNLYGKHYFRLLLFLYLLY------IGIFTLCCVYRP
----LKDA-PE---NYT------RSEMDKTIRVQKTLNESYVTHE-DNLRLAGEVISVLG
AVAILLLEIPDILRVGAK--RYFGQTALGGPFHVI------------LISYACLVVLLCV
FRASEVQREDLVMAVCLVLGWCNVMFFARGFEMLGPYVIMIQK-----------------
-------------IIFGDLTKFMWLTMIVLVGFST---SLWMVYMTQE------------
----PDS------------------IPAYRS------FPITLFSQFELSVGLIDLP----
---VDHTIITPPIVHVIHCAFSVVSYILLLNLLIAM-MSDTHWRVAQERDELWRTQVVAT
TLSLERRL--------PR-----------WLWPR-LGVCGLGYGLK--------------
----------------ERWYL-----RVEDRNDSMMQKMRRYIKVFSKEEEK--------
-------------------E-KD--------G-----MEKTDSTRKS-------------
-------------------------------------------------GSGTPRLR---
------PKTSGG---------PNDRKSLTGWQ-----------------VIRYSTL----
-GLE---Q----------EPEEPEEDQNIKVV-------------------
>POEFO05368_HOG_0033281_Poeciliaformosa
-------MSPSLARS----------------APSELNHW----WTQLRFRL-------QN
KKG-WNEM-----------------------------------------------LD---
-----------ETFLYY----------------------------------TKN------
INDI-----------------------------------------P----------L---
-----FYAAKNNSAGCIKKLLSC---------------------------------ASTN
IFER------------------GS--LGETALHVAVMN---DNLDAAMALMDGAPD----
---------------------------------------LINEPMTSELF----------
---------------------------QGS------------------------SVTPLH
IAVVNQNLNLVRHLISRGGDVINPRVTGLYFRKRIGG-LFYC-GEHILSFAACTGNEDII
AMLID---AGASTRIQDYLGNT-----LLHILVLQPNKT---------------------
--------TACQ---------AIDLILARDVE-LDQPVPLDM------------------
------VPNNRGLTPFKLAAKEGNIV-----------VFQHLVNK--------------R
R-VVQW------SLGPLSSHL-----YDLTEIDSWAD-----------------------
----------TMSVLEVIVG-SQKRE----------------------------------
------------------------------------------------------------
------ARRILEVTPVRQLVRLKWNLYGKYYLRLLLLLYLLY------IGTFTLSCIFRP
----LKDA-DR---NYT------DTDLDKTIRVQKTLNESYVTYG-DSLRLAGEVISVLG
AILILVLEIPDILRVGAK--RYFGQTALGGPFHVI------------LISYATLVVLLCV
FRACEVHGEREVMAVCLLLGWCNVMFFARGFEMLGPYVIMIQK-----------------
-------------IIFGDLTKFMWLSVIILIGFST---SLWMVYMTQD------------
----PSS------------------IPQYTS------YPITLFSVFELSVGLIDLP----
---VDHTFITPPIVHVLHVCLSIVCYMLLSNVLIAM-MSDTQWRVAQERDELWRTQVVAT
TLMLERRL--------PR-----------CLWPR-LGVCGLSFGLK--------------
----------------ERWYL-----RVEDRNDPMMQKMRRYVKVFSSLDEK--------
-------------------E-----------G-----VEKSDSAK---------------
---------------------------------------------------DSPVLR---
------HKNT------------GKRKAQEGWD-----------------MIRNSAF----
-GLEMEQM----------EQKEPMEIQDIRYV-------------------
>Fundulus_heteroclitus_XP_012730583.1
-------MSPSLARS----------------APSELNHW----WTQLRFRL-------QN
KKG-WNEM-----------------------------------------------LD---
-----------ETFLYY----------------------------------TKN------
INDI-----------------------------------------P----------L---
-----FYAAKNNSVGCIKKLLSC---------------------------------SSTN
IFER------------------GA--LGETALHVAVMN---DNLDAAVALMDGAPD----
---------------------------------------LINEPMTSELF----------
---------------------------QG--------------------------VTPLH
IAVVNQNLNLVHHLISRGGDVINPRVTGLYFRKRIGG-LLYC-GEHILSFAACAGNEDII
SMLID---AGASTRIQDYLGNT-----LLHVLVLQPNKT---------------------
--------TACQ---------AIDLILARDVE-LDQSVPLDM------------------
------VPNNRGLTPFKLAAKEGNIV-----------VFQHLVNK--------------R
R-VVQW------SLGPLSSHL-----YDLTEIDSWAD-----------------------
----------NMSVLEVIVG-GQKRE----------------------------------
------------------------------------------------------------
------ARGILEVTPVRQLVSLKWNLYGKHYFRLLLFLYLLY------IGTFTLCCVFRP
----LKDA-ER---NYT------DEDLDKTVRVQKTLNESYVTYG-DSLRLAGEIISVLG
AILILVLEIPDILRVGAK--RYFGQTALGGPFHVI------------LISYASLVVLLCV
FRACEVHGEAEVMALCLVLGWCNVMFFARGFEMLGPYVIMIQK-----------------
-------------IIFGDLTKFMWLSFIVLIGFST---SLWMVYMTQY------------
----PGS------------------LPAYTS------FPITLFSQFELSVGLIDLP----
---VDHSFITPPIVHVLHVSFSVVSYILLLNLLIAM-MSDTHWRVAQERDELWRTQVVAT
TLMLERRL--------PR-----------CLWPR-LGVCGLSYGLK--------------
----------------ERWYL-----RVEDRNDPMMQKMRRYVKVFSSLDEK--------
-------------------E-----------G-----LEKSDSMK---------------
---------------------------------------------------ETPVLR---
------PKNRRH----------GNSKAQAGWE-----------------MIRHSAL----
-GLE---M----------EPEEPGEIQDIRYV-------------------
>Cyprinodon_variegatus_XP_015226291.1
-------MSPSLARS----------------APSELNHW----WNQLRFRL-------QN
KKG-WNEM-----------------------------------------------LD---
-----------ETFLYY----------------------------------TKN------
INDI-----------------------------------------P----------L---
-----FYAAKINSAGCIKKLLSC---------------------------------ASTN
IFER------------------GA--LGETALHVAVMN---DNLDAAVALMDGAPE----
---------------------------------------LINEPMTSELF----------
---------------------------QG--------------------------ITPLH
IAVVNQNLNLVHHLISRGGDVINPRVTGLYFRKRIGG-LLYC-GEHILSFAACAGNEEII
SMLID---AGASTRIQDYLGNT-----LLHVLILQPNKT---------------------
--------TACQ---------AIDLILARDAE-LDQSIPLDM------------------
------VPNNRGLTPFKLAAKEGNIV-----------VFQHLVNK--------------R
R-VVQW------SLGPLSSHL-----YDLTEIDSWAD-----------------------
----------SMSVLEVIVG-SQKRE----------------------------------
------------------------------------------------------------
------ARGILEVTPVRQLVSLKWNLYGKHYFRLLLFLYLLY------IVTFTLCCVFRP
----LKDA-DG---NYT------ETDLDKTIRVQKTLNDSYVTYG-DSVRLAGEVISVLG
ALLILVLEIPDILRVGAK--RYFGQTALGGPFHVI------------LISYACLVVLLCV
FRTCEVQGEAEVMALCLVLGWCNVMFFARGFEMLGPYVIMIQK-----------------
-------------IIFGDLTKFMWLSFIVLIGFST---SLWIVYMTQD------------
----PNS------------------LPAYNS------FPITLFSQFELSVGLIDLP----
---VDHTFITPPIVHVLHASFSVVSYILLLNLLIAM-MSDTHWRVAQERDELWRTQVVAT
TLMLERRL--------PR-----------CLWPR-LGVCGLSFGLK--------------
----------------ERWYL-----RVEDRNDPMMQKMRRYVKVFSSLDEK--------
-------------------E-----------G-----NEKSDTMK---------------
---------------------------------------------------ETPMLR---
------PKNRGY----------GNRKAQAGWE-----------------MIRNSAL----
-GLE---M----------EQEEPGEMQDIRYV-------------------
>XIPMA16621_HOG_0033281_Xiphophorusmaculatus
---------PSVS--------------------YELNHW----WTQLRFRL-------QN
KKG-WSEM-----------------------------------------------LD---
-----------ETFLYY----------------------------------TKN------
INDI-----------------------------------------P----------L---
-----FYAAKNNSVGCIKKLLSC---------------------------------SSTN
IFER------------------GS--LGETALHVAVMN---DNLDAAVALMDGAPD----
---------------------------------------LINEPMTSELF----------
---------------------------QG--------------------------VTPLH
IAVVNQNLNLVRHLISRGGDAINPRVTGLYFKKRMGG-HLYF-GEHTLSFAACTGNEDII
TMLID---AGASTRIQDYLGNT-----LLHILVLQPNKT---------------------
--------TACQ---------AIDLILTRDAE-LDQPVPLDM------------------
------VPNNRGLTPFKLAAKEGNIV-----------VFQHLVNK--------------R
R-VLQW------SLGPLSSHL-----YDLTGIDSWAD-----------------------
----------NMSVLEVIVG-SQKRE----------------------------------
------------------------------------------------------------
------ARGILEVTPVKQLVSMKWNLYGKHYLRLLLALYLLY------ILTFTVCCMCRP
----LKDA-ER---NYT------DTDLDKTIRVQKTFNESYVTYG-DSLRLAGEVISVLG
AILILLLEIPDILRVGAK--RYFGQTALGGPFHVI------------LISYAALVVLLCV
FRACEVHREREVMALCLVLGWCNVMFFARGFEMLGPYVIMIQK-----------------
-------------VIFGDLTKFMWLSAIVLVGFST---ALWTVYMTQV------------
----PGS------------------IPAYTS------FPITLFSLFELSVGLIDLP----
---VDHTFTTPPIIHVLHFCFSVFCYTLLINLLIAM-MSDTHWRVAQERDELWRTQVVAT
TLMLERRL--------PR-----------CLWPR-LGVCGLSYGLK--------------
----------------ERWYL-----RVEDRNDPMMQKMRRYVKVFSSLNEM--------
-------------------E-----------G-----SEKSDSTK---------------
---------------------------------------------------DVPVRE---
------RQNT------------GKRKAQAGWE-----------------MIRNSAL----
-GLE---M----------EQEEPVDIQDIRYV-------------------
>Kryptolebias_marmoratus_XP_017270869.1
-------MSPSLARS----------------APSELNHW----WTQLRFRL-------QN
KKG-WNEM-----------------------------------------------LD---
-----------ETFLLY----------------------------------TKN------
INDI-----------------------------------------P----------L---
-----FYAAKVNSPGCIKKLLSC---------------------------------SSTN
IFER------------------GA--LGETALHVAVMN---DNLDAAVALMEGAPE----
---------------------------------------LINEPMTSEIF----------
---------------------------QG--------------------------VTPLH
IAVVNQNINLVHQLISCGGDAATPRVTGLYFRKRIGG-LLYC-GEHILSFAVCAGNEEII
NMLID---AGASTRVQDYRGNT-----LLHILVLQPNKT---------------------
--------TACQ---------AIDLIMTRDAE-LDQPLPLDM------------------
------VPNYRGLTPFKLAAKEGNIV-----------AFQHLVNK--------------R
R-VVQW------SLGPLTSHL-----YDLTEIDSWAD-----------------------
----------NMSVLELIVG-SPKRE----------------------------------
------------------------------------------------------------
------ARGILEVTPVRQLVSLKWNLYGKHYFRLLLLLYLLY------IGTFTLCCVFRP
----LKDA-DR---NYT------ESDYDKTIRVQKTLNESYVTHE-DSLRLAGEIISVLG
AIVILVLEIPDILRVGAK--RYFGQTALGGPFHVI------------LISHASLVVLLCV
FRPCGVQGEAEVMAVSLVLGWCNVMFFARGFEMLGPYVIMIQK-----------------
-------------IIFGDLTKFMWLTVIVLIGFST---SLWMVYMTQD------------
----PES------------------LPAYRS------FPITLFSQFELSVGLIDLP----
---VDHTFRTPPIVHVLHIAFSVVSYILLLNLLIAM-MSDTHWRVAQERDELWRTQVVAT
TLMLERRL--------PR-----------CLWPR-LGVCGLSYGLK--------------
----------------ERWYL-----RVEDRNDPMMQKMRRYVKVFSKEDEK--------
-------------------E-KE--------A-----QEKCDTSK---------------
---------------------------------------------------GSPMLR---
------SKTREG----------RSRKALAGWE-----------------VIRHSAL----
-GLE---M----------EQEEPQEIQDIRYV-------------------
>Hippocampus_comes_XP_019724545.1
-------MSPALARS----------------APSELNHW----WSQLKFRF-------HH
KKG-WNQM-----------------------------------------------LD---
-----------ETFLLH----------------------------------TKC------
VTDI-----------------------------------------P----------L---
-----FYAAKKNSAGCIKKLLGC---------------------------------SSTN
IFER------------------GA--LGETALHVAAMN---DNLDAAVALMDGAPE----
---------------------------------------LINEPMTSDLF----------
---------------------------QG--------------------------VTPLH
IAVVNQNFDLVHQLVSRGADVATPRVTGLYFRKRIGG-LIYC-GEHILSFAACAGNEDII
SMIID---AGASTRVQDYRGNT-----VLHVLVLQPNKT---------------------
--------IACQ---------AIDLIMARDAE-LDQSVPLDM------------------
------VPNSRGLTPFKLAAKEGNSV-----------AFQHLVNK--------------R
R-LVQW------GLGPLTSHL-----YDLSEIDSWAD-----------------------
----------NMSVLELIVG-SPQKE----------------------------------
------------------------------------------------------------
------ARRILEVTPVRQLVSLKWNLYGKHYFRLLMVFYLLY------IGMFTLCCIFRP
----LKDA-PE---NYT------ISDMDKTIRVQKTLRESYVTHA-DTLRLVGEIISVLG
ALVILLLEIPDILRMGAK--RYFGQTALGGPFHVI------------LVSYACLVVLLCV
FRACSVQGEAEVMAVCLVLGWTNVMFFARGFEMLGPYVIMIQK-----------------
-------------IIFGDLTKFMWLSVIVLLGFSA---SLWMVYMTQE------------
----PDT------------------IPAYRS------FPITLFSQFELSVGLIDLP----
---VDHTFSTPPIVHVLHCAFSVVSYILLLNLLIAM-MSDTHWRVAQERDELWRTQVVAT
TLMLERRL--------PR-----------CLWPR-LGVCGLSYGLT--------------
----------------ERWYL-----RVEDRNDPLMQKMRRYIQVFAREDEK--------
------------------GE-KE--------G-----TQKADANL---------------
------------------------------------------------------KVR---
------PR---------------NRRSISGWK-----------------LIRQSAL----
-GAD---V----------EVEEPEDEQDIHFV-------------------
>ORYLA05838_HOG_0033281_Oryziaslatipes
-------MSPSLARS----------------APSELNHW----WTQLRFRL-------QN
KKG-WNEM-----------------------------------------------LD---
-----------ETFLLY----------------------------------TKN------
TNDI-----------------------------------------P----------L---
-----FYAAKTNSVGCIKKLLSC---------------------------------ASTN
IFER------------------GA--LGETALHVAVIN---DNLDAAVALMDGAPE----
---------------------------------------LINEPMTSELF----------
---------------------------QG--------------------------VTPLH
IAVVNRNINLVQHLISRGGDVCTPRVTGLYFRKRIGG-LIYY-GEHALSFAACVGNEDIV
SMLID---AGASTRVQDSRGNT-----VLHLLVLQPNKT---------------------
--------IACQ---------TMDLIMARDAE-LDQPVPLDM------------------
------VTNYRGLTPFKLAAKEGNTV-----------VFQHLVNK--------------R
R-VIQW------SLGPLSSHL-----YDLTEIDSRAD-----------------------
----------NTSVLELIVA-SPRRE----------------------------------
------------------------------------------------------------
------ARGVLEVTPVRQLVSLKWNLYGKHYFRLLLFLYILY------IGCFTLCCVFRP
----LKDI-PE---NYT------KSDSDYTIKIQKTLKESYVTYS-DSLRLVGEVISVLG
AVLILFLEIPDMIRVGAK--RYFGQTALGGPFHVI------------LISYASLVVLLCV
FRLCEVQGEAEVMALCLVLGWCNVMFFARGFEMLGPYVIMIQK-----------------
-------------IIFGDLTKFMWLSLIVLIGFST---SLWMVYMTQD------------
----PSS------------------LPMYRS------FPITLFSEFELSLGMIDLP----
---VDHTLKTPSIVHVVHVAFTFVCSTLLINLLIAM-ISDTIWRVGQERDELWRTQVVAT
TLMLERRL--------PL-----------CLWPR-LGVCGLNYGLK--------------
----------------ERWYL-----RVEDRNDAVMQKMRRYVKAFSKEDEK--------
-------------------Q-KE--------G-----LEKADVT----------------
-------------------------------------------------------LR---
------SQNKNS----------MRSKAQAGWE-----------------VIRQSTL----
-GLE---M----------EQEGPEEDQNIKFV-------------------
>ORENI04954_HOG_0033281_Oreochromisniloticus
-------MSPSLARS----------------APSELNHW----WSQLKFRL-------QN
KKG-WNEM-----------------------------------------------LD---
-----------ETFLLY----------------------------------TKG------
VNDI-----------------------------------------P----------L---
-----FYAAKNNSAGCIKKLLGC---------------------------------ASTN
IFER------------------GS--LGETALHVAVMN---DNLDAAVALMDGAPD----
---------------------------------------LINEPMTSELF----------
---------------------------QG--------------------------ITPLH
IAVVNQNIDLVRHLISRGGDVSTPRVTGLYFRKRIGG-LMYC-GEHILSFAACAGNMDII
SMVID---AGASTRIQDYKGNT-----VLHILVLQPNKN---------------------
--------IACQ---------VIDLIMARDAE-LDQQVPLDM------------------
------VPNSRGLTPFKLAAKEGNIV-----------IFQHLVNK--------------R
R-VVQW------SLGPLTSHL-----YDLSEIDSWAD-----------------------
----------SMSVLEVIVA-SQQKE----------------------------------
------------------------------------------------------------
------ARKILEVTPVRQLVSLKWNLYGKHYFRFLLFLYLLY------IGTFTLCCMFRP
----LKKA-PE---NYT------TSDADKTVWVQKTLKESYTTHG-DNVRLAGEIISVIG
AFVILVLEIPDILRVGAK--RYFGQTALGGPFHVI------------LISYACLVVLLLV
FRVCEVQREAEVMAVCLVLGWCNVMFFARGFEMLGPYVITIQK-----------------
-------------IIFGDLTKFMWLISIVLFAFST---SLWIVYMTQE------------
----VDS------------------LPAYHS------YPISLFSQFELSVGLIDLP----
---VDHTIPIPAIVYVLHCTSSLVSHILLLNLLTAM-MSDTQWRVGQERDELWRTQVVAT
TLMLERRL--------PR-----------CLWPR-LGVCGLNYGLK--------------
----------------ECWYL-----RVEERNDSMLQKMRRYINVFSKEDEK--------
-------------------E-TE--------A-----EENSDFK----------------
---------------------------------------------------GTLKLR---
------LKNKGG-----------------WWE-----------------LVRHSAL----
-GLE---M----------EQDEAEEEQDIKYV-------------------
>Maylandia_zebra_XP_004550805.1
-------MSPSLARS----------------APSELNHW----WSQLKFRL-------QN
KKG-WNEM-----------------------------------------------LD---
-----------ETFLLY----------------------------------TKG------
VNDI-----------------------------------------P----------L---
-----FYAAKNNSAGCIKKLLGC---------------------------------ASTN
IFER------------------GS--LGETALHVAVMN---DNLDAAVALMDGAPD----
---------------------------------------LINEPMTSELF----------
---------------------------QG--------------------------ITPLH
IAVVNQNIDLVRHLISRGGDVSTPRVTGLYFRKRIGG-LMYC-GEHILSFAACAGNMDII
SMVID---AGASTRIQDYKGNT-----VLHILVLQPNKN---------------------
--------IACQ---------VIDLIMARDAE-LDQQVPLDM------------------
------VPNSRGLTPFKLAAKEGNTV-----------IFQHLVNK--------------R
R-VVQW------SLGPLTSHL-----YDLSEIDSWAD-----------------------
----------SMSVLEVIVA-SQQKE----------------------------------
------------------------------------------------------------
------ARKILEVTPVRQLVSLKWNLYGKHYFRFLLFLYLLY------IGTFTMCCMFRP
----LKNA-PE---NYT------TSDADKTVWVQKTLKESYTTHG-DNVRLAGEIISVIG
AFVILVLEIPDILRVGAK--RYFGQTALGGPFHVI------------LISYACLVVLLCV
FRACEVQREAEVMAVCLVLGWCNVMFFARGFEMLGPYVITIQK-----------------
-------------IIFGDLTKFMWLISIVLFAFST---SLWIVYMTQE------------
----VDS------------------LPAYRS------YPISLFSQFELSVGLIDLP----
---VDHTIPIPAIVHVLHCTSSLVSHILLLNLLTAM-MSDTQWRVGQERDELWRTQVVAT
TLMLERRL--------PR-----------CLWPR-LGVCGLNYGLK--------------
----------------ECWYL-----RVEERNDSMMQKMRRYVNVFSKEDEK--------
-------------------E-TE--------G-----DENSDFK----------------
---------------------------------------------------GTLKLR---
------LKNKGG-----------------WWE-----------------LVRHSAL----
-GLE---M----------EQDEPEEEQSIKYV-------------------
>Haplochromis_burtoni_XP_005925341.1
-------MSPSLARS----------------APSELNHW----WSQLKFRL-------QN
KKG-WNEM-----------------------------------------------LD---
-----------ETFLLY----------------------------------TKG------
VNDI-----------------------------------------P----------L---
-----FYAAKNNSAGCIKKLLGC---------------------------------ASTN
IFER------------------GS--LGETALHVAVMN---DNLDAAVALMDGAPD----
---------------------------------------LINEPMTSELF----------
---------------------------QG--------------------------ITPLH
IAVVNQNIDLVRHLISRGGDVSTPRVTGLYFRKRIGG-LMYC-GEHILSFAACAGNMDII
SMVID---AGASTRIQDYKGNT-----VLHILVLQPNKN---------------------
--------IACQ---------VIDLIMARDAE-LDQQVPLDM------------------
------VPNSRGLTPFKLAAKEGNTV-----------IFQHLVNK--------------R
R-VVQW------SLGPLTSHL-----YDLSEIDSWAD-----------------------
----------SMSVLEVIVA-SQQKE----------------------------------
------------------------------------------------------------
------ARKILEVTPVRQLVSLKWNLYGKHYFRFLLFLYLLY------IGTFTMCCMFRP
----LKNA-PE---NYT------TSDADKTVWVQKTLKESYTTHG-DNVRLAGEIISVIG
AFVILVLEIPDILRVGAK--RYFGQTALGGPFHVI------------LISYACLVVLLCV
FRACEVQREAEVMAVCLVLGWCNVMFFARGFEMLGPYVITIQK-----------------
-------------IIFGDLTKFMWLISIVLFAFST---SLWIVYMTQE------------
----VDS------------------LPAYRS------YPISLFSQFELSVGLIDLP----
---VDHTIPIPAIVHVLHCTSSLVSHILLLNLLTAM-MSDTQWRVGQERDELWRTQVVAT
TLMLERRL--------PR-----------CLWPR-LGVCGLNYGLK--------------
----------------ECWYL-----RVEERNDSMMQKMRRYVNVFSKEDEK--------
-------------------E-TE--------G-----DENSDFK----------------
---------------------------------------------------GTLKLR---
------LKNKGG-----------------WWE-----------------LVRHSAL----
-GLE---M----------EQDEPEEEQSIKYV-------------------
>Pundamilia_nyererei_XP_005732007.1
-------MSPSLARS----------------APSELNHW----WSQLKFRL-------QN
KKG-WNEM-----------------------------------------------LD---
-----------ETFLLY----------------------------------TKG------
VNDI-----------------------------------------P----------L---
-----FYAAKNNSAGCIKKLLGC---------------------------------ASTN
IFER------------------GS--LGETALHVAVMN---DNLDAAVALMDGAPD----
---------------------------------------LINEPMTSELF----------
---------------------------QG--------------------------ITPLH
IAVVNQNSDLVRHLISRGGDVSTPRVTGLYFRKRIGG-LMYC-GEHILSFAACAGNLDII
SMVID---AGASTRIQDYKGNT-----VLHILVLQPNKN---------------------
--------IACQ---------VIDLIMARDAE-LDQQVPLDM------------------
------VPNSRGLTPFKLAAKEGNTV-----------IFQHLVNK--------------R
R-VVQW------SLGPLTSHL-----YDLSEIDSWAD-----------------------
----------SMSVLEVIVA-SQQKE----------------------------------
------------------------------------------------------------
------ARKILEVTPVRQLVSLKWNLYGKHYFRFLLFLYLLY------IGTFTMCCMFRP
----LKNA-PE---NYT------TSDADKTVWVQKTLKESYTTHG-DNVRLAGEIISVIG
AFVILVLEIPDILRVGAK--RYFGQTALGGPFHVI------------LISYACLVVLLCV
FRACEVQREAEVMAVCLVLGWCNVMFFARGFEMLGPYVITIQK-----------------
-------------IIFGDLTKFMWLISIVLFAFST---SLWIVYMTQE------------
----VDS------------------LPAYRS------YPISLFSQFELSVGLIDLP----
---VDHTIPIPAIVHVLHCTSSLVSHILLLNLLTAM-MSDTQWRVGQERDELWRTQVVAT
TLMLERRL--------PR-----------CLWPR-LGVCGLNYGLK--------------
----------------ECWYL-----RVEERNDSMMQKMRRYVNVFSKEDEK--------
-------------------E-TE--------G-----DENSDFK----------------
---------------------------------------------------GTLKLR---
------LKNKGG-----------------WWE-----------------LVRHSAL----
-GLE---M----------EQDEPEEEQSIKYV-------------------
>Neolamprologus_brichardi_XP_006802978.1
-------MSPSLARS----------------APSELNHW----WSQLKFRL-------QN
KKG-WNEM-----------------------------------------------LD---
-----------ETFLLY----------------------------------TKG------
VNDI-----------------------------------------P----------L---
-----FYAAKNNSAGCIKKLLGC---------------------------------ASTN
IFER------------------GS--LGETALHVAVMN---DNLDAAVALMDGAPD----
---------------------------------------LINEPMTSELF----------
---------------------------QG--------------------------ITPLH
IAVVNQNIDLVRHLISRGGDVFTPRVTGLYFRKRIGG-LMYC-GEHILSFAACAGNMDII
SMVID---AGASTRIQDYKGNT-----VLHILVLQPNKN---------------------
--------IACQ---------VIDLIMARDAE-LDQQVPLDM------------------
------VPNSRGLTPFKLAAKEGNTV-----------VFQHLVNK--------------R
R-VVQW------SLGPLTSHL-----YDLSEIDSWAD-----------------------
----------SMSVLEVIVA-SQQKE----------------------------------
------------------------------------------------------------
------ARKILEVTPVRQLVSLKWNLYGKHYFRFLLFLYLLY------IGTFTMCCMFRP
----LKNA-PE---NYT------TSDADKTVWVQKTLKESYTTHG-DNVRLAGEIISVIG
AFVILVLEIPDILRVGAK--RYFGQTALGGPFHVI------------LISYACLVVLLCV
FRACEVQREAEVMAVCLVLGWCNVMFFARGFEMLGPYVITIQK-----------------
-------------IIFGDLTKFMWLISIVLFAFST---SLWIVYMTQE------------
----VDS------------------LPSYRS------YPVSLFSQFELSVGLIDLP----
---VDHTIPIPAIVHVLHCTSSLVSHILLLNLLTAM-MSDTQWRVGQERDELWRTQVVAT
TLMLERRL--------PR-----------CLWPR-LGVCGLNYGLK--------------
----------------ECWYL-----RVEERNDSMMQKMRRYVNVFSKEDEK--------
-------------------E-TE--------G-----DENSDFK----------------
---------------------------------------------------VPLKLR---
------LKNKGG-----------------WWE-----------------LVRHSAL----
-GLE---M----------EQDEPEEEQSIKYV-------------------
>GADMO18626_HOG_0033281_Gadusmorhua
-------MAPCLARS----------------APSDLNHW----WNQLRFRL-------QN
KKG-WTEM-----------------------------------------------LD---
-----------ETFLLC----------------------------------TKX------
--------------------------------------------------------L---
-----FFAAKKNSAGCVKKLLGC---------------------------------ASTN
IFER------------------GA--LGETALHIAVMN---DNVDAAVALMDGAPE----
---------------------------------------LSNEPMTSELM----------
---------------------------QG--------------------------VTPLQ
IAVVNQNITLVGQLIARGGDAATPRVTGLYFKKRPGG-LVYYADEHILSFAACMGNEYIM
TM-----------------XNT-----VLHILVMQPNKT---------------------
--------IACQ---------AMDLILSRDVE-LDHSLPLDM------------------
------VPNYKELTPFKLAAKEGNVV-----------AFQHLVNK--------------R
R-VLQW------SLGPLTSNL-----YDLSEIDSWAD-----------------------
----------DLSVLELIVG-SPQRE----------------------------------
------------------------------------------------------------
------ARRILEVTPVRQLVSLKWNLYGKHYFRLLLVLYLLY------IGTFTLCCVFRP
----LKDT-PE---NYT------TSEMDKTIRVQKTLSESYVTYE-DSLRLAGEILSVLG
AILILLLEIPDILRVGAK--RYFGQTAL-------------------XISYACLVVLLCV
ARASELGGEDVLMALCLVLGWSNVMFFARGFEMLGPYVIMIQK-----------------
-------------IIFGDLTKFMWLSFIVLIGFST---SLWMVYMTQD------------
----PES------------------IPAYRS------FPITLFSQFELSVGLIDLP----
---VDHTFYTPPIVHVLHCTFSVVSYILLLNLLIAM-MSDTHWRVAQERDELWRTQVVAT
TLMLERRL--------PR-----------CLW-----VCGLNYGLK--------------
----------------QMWYL-----RVEDRNDLMVQKMRRYINAFAKDARV--------
---------------VPPRE-RR--------G------RKAGSG----------------
---------------------------------------------------GGPELR---
------SKSRGG---------ASTRHA--GWQ-----------------AIRRSAL----
-SMD---L-------------EPEYEE------------------------
>Clupea_harengus_XP_012688915.1
-------MAPSLARS----------------APGEINHW----WSHLRFRL-------QN
KKG-WNEM-----------------------------------------------LD---
-----------ETFLLQ----------------------------------AQQ------
INNI-----------------------------------------P----------L---
-----FFATKGNNVGCIKKLLSC---------------------------------ASTN
IFER------------------GA--LGETALHVAALN---DNLEAAVTLMDEAPE----
---------------------------------------LINEPMISDLY----------
---------------------------QG--------------------------MTALH
IAVVNQNVNLVRELIRRGGDGATPRVTGMYFRKRRGG-LLYY-GEHILAFASCVGNEEII
NMLIN---NGANVRAQDTCGNT-----ILHILVMQPNRT---------------------
--------IACQ---------VVDLLLSRDAE-MDPIIALDM------------------
------VPNYRGITPFKLAAKEGNVV-----------AFQHLVNR--------------R
R-IVQW------SLGPLTSNL-----YDLTEIDSWSD-----------------------
----------ELSVLELIAG-SQRRE----------------------------------
------------------------------------------------------------
------ARRILEVTPVRQLVSLKWNLYGKHYFRLLLLFYLLY------IGTFTLCCVHRP
----LKDI-PE---NYT------LPENDKTIKIPKTLEESYLTYK-DRLRLAGEIISVLG
ALIILLLEIPDILRVGAK--RYFGQTALGGPFHVI------------LIGYASLVVILCV
LRATETPGESVLMAICLVLGWSNVMYFARGFQMLGPYVIMIQK-----------------
-------------IIFGDLTKFMWLSFIVLMGFST---ALWMVYMTQE------------
----PFS------------------LPAYSS------FPITLFSQFELSVGLIDLP----
---VEHELLTPAIVHVLHCCFSVVSYILLLNLLIAM-MSDTHWRVAQERDELWRTQVVAT
TLMLERRL--------PR-----------WLWPR-LGVCGLLYGLG--------------
----------------ERWYL-----RVEDRNDPLVQKMRRYISVFTKDDDQ--------
---------------VRHKE--E--------------PEKIDPSSDP-------------
-------------------------------------------------VSGEALTK---
------PIQRGG--------ANPNRKSLRGWQ-----------------KIRQSTL----
-GFD-----------------TDCDGQDIQYV-------------------
>Pygocentrus_nattereri_XP_017561597.1
-------MAPPLSRS----------------APAEINHW----WSQIRFRL-------QN
RKG-WNEM-----------------------------------------------LD---
-----------ETFLLQ----------------------------------SKR------
VNDI-----------------------------------------P----------L---
-----FYATKTNSVGCIKKLLDC---------------------------------STTN
IFER------------------GP--LGETALHVAVMH---DNQEASVALMKGAPE----
---------------------------------------LINEPMTSELY----------
---------------------------EG--------------------------VTALH
IAVINQNVNLVRELIDRGADVTSPRATGMYFRKRRGG-LVYY-GEHIMAFACCQGNEEII
NMLVK---AGANIRAQDSQGNT-----IMHILIMQPNKI---------------------
--------IACQ---------ILDLLLGLDAE-LDPAVPLDM------------------
------VPNYRGLTPFKLAAKKGNIV-----------AFQHMVNR--------------R
R-IVQW------SLGSLTSYL-----YDLTEIDSRTD-----------------------
----------DISVLELIVC-SQRRE----------------------------------
------------------------------------------------------------
------ARRILELTPVQQLITMKWNLYGKYYFRLLMLVYLLY------IGTFTLCCMHRP
----LKDI-PE---NYT------KSSMDQTIKIQKTLKESYVTYG-DHLRLVGEIISVIG
ALIILLLEIPDILRVGAK--RYFGQTALGGPFHVT------------LITYAVLVVFLCI
LRTSEMPGEMVLMAVCLVLGWCNVLYFARGFEMLGPYVIVIQK-----------------
-------------ILFGDLTKFMWLSLIALIGFST---ALWTVYMTQE------------
----PFS------------------IPSYHS------FPITLFTEFELTIGLIDLP----
---VDNTIYTHPIVHVVHCCFSVVSHLLLLSLLTAM-MSDTQWRVGQERDELWRTQVVAT
TLMLEQRL--------PR-----------SLWPR-LGVCGLLYGLG--------------
----------------ERWYL-----RVEDRSDQFVQKIRRYANVFAKNEEA--------
-----------------EKE-----------------PEKNNSAGKQ-------------
------------------------------------------------------------
------TEGKGA----QDDASHPDRKSVECWQ-----------------ILRNSVL----
-GGD---V----------EKEEHWGAHEMKCV-------------------
>Ictalurus_punctatus_XP_017334756.1
-------MAPPLSRS----------------APRNIVRC----WNQLKYRL-------QN
RKG-WDEV-----------------------------------------------LD---
-----------ETFLYQ----------------------------------SKR------
ENEI-----------------------------------------P----------L---
-----FHATKANNVGCIRKLLDC---------------------------------STTN
IFER------------------GA--LGETALHVAVIN---DNLEAAVALMEGAPE----
---------------------------------------LINEPMTSELY----------
---------------------------QG--------------------------ITALH
IAVINQNINIVQELIHRGADVTTPRVTGIYFSKRKGG-LFYY-GEHILSFACCIGNEEII
TMLIK---SGANIRAQDSLGNT-----IPHILVLQPTKI---------------------
--------IACQ---------IMDMLLTLDAE-LEPSLPLDM------------------
------VPNYRGLTPFKLAAKKGNVV-----------AFQHIVNR--------------R
R-IVQW------SLGSLNSYL-----YDLAEIDSRTD-----------------------
----------DISVLELIVS-SQKRK----------------------------------
------------------------------------------------------------
------ARKILELTPVQQIINLKWNLYGKFYFRLLLLVYLLY------IGTFTLCCMHRP
----LKHI-PE---NYT------KAANDPTTMIQKTLKESYVSYA-DHLRLGGELISVIG
AIIILLLEIPDILRVGAK--RYFGQTALGGPFHVT------------LIAYAVLVVSLCV
LRLTEMPGETGVMASCLVLGWCNVLYFARGFEMLGPYVIVIQK-----------------
-------------IIFGDLTKFMWLSAIALLGFST---AQWTVYMTQD------------
----HMS------------------VPAMRS------YPITLFTMFELTVGLIDMP----
---VDHTIHTHPIVHVIDCCFSVVSHLLLLSLLTAM-MSDTQWRVAQERDELWRTQVVAT
TLMLEHRL--------PR-----------CLWPR-LGMCGLSYGLG--------------
----------------DRWFL-----RVEDRSDQFMQKIRRYANVLAKNEDSN-------
-----------------KNE-----------G-----CESNDMAHDP-------------
------------------------------------------------------------
------TNTKSM----QNDSSNGNRKSVLCWQ-----------------IIRQSLL----
-GLE---M----------ENTEQLGAQEMKPV-------------------
>LEPOC10382_HOG_0033281_Lepisosteusoculatus
-------MPPPLALT----------------APGQIGHW----WSRLRFRL-------QH
KKD-WTQV-----------------------------------------------LD---
-----------ETFLLQ----------------------------------SKR------
IKDS-----------------------------------------P----------L---
-----FFAAKENDVMSIRKLLKC---------------------------------PSTD
IFER------------------GA--LGETALHVAVMF---DNLEASVALIEGVPD----
---------------------------------------LINEPMSSDVY----------
---------------------------EG--------------------------MTAMH
IAVLNQNVNLVRELIARGADVATPRVTGSYFKKRRKG-LVYF-GEHILCFASCVGNEEIV
NMVIE---AGANLRAQDYLGNT-----VLHILILQPNKM---------------------
--------ISCQ---------IFDLLMAADGK-TDRGVPLDV------------------
------LPNFRGLTPFKLAAKEGNVV-----------MFQHMVSK--------------R
R-SLQW------SLGPLSSYL-----YDLSEIDSWSD-----------------------
----------DCSVLELVVC-SSKRE----------------------------------
------------------------------------------------------------
------ARRILDVSPVRQLVSLKWNLYGKHYFRFLLLLYLLY------IGTFTLCCTFRP
----LKPI-PE---NYS------LEHTDITIFVQKTLEESYISYE-DHLRLVGEIISVVG
ALVILLLEIPDILRVGAK--RYFGQTVLGGPFHVI------------LITYACLVLVLLI
LRLSSSEGEAVVMALSLVLGWCNVMYFARGFEMLGPYVIMIQK-----------------
-------------IIFGDLTKFIWLSVLVLVGFST---ALWMTYMTFD------------
----YTQ-----------------GIPSYKS------FPVSLFSQFELSMGMIDLP----
---VDQTVPTPPIVHILHIMFSVVSCLLLLNLLIAM-MSDTHWRVAQERDELWRAQVVAT
TIMLERRL--------PR-----------CMWPQ-MGICGQEYGLG--------------
----------------DRQYL-----RVEDHRSQAMKKIWHYANAFLEKGEG--------
---------------LGEKE--Q--------------GRETDLSAGRVV-----------
----------------------------------FR------------------------
------SRQKGR--------TMLNRKSLGAWE-----------------MIRRSAL----
-GSE-HGL-------------TNLDAVEVELN------------------V
>Sea_lamprey_ENSPMAG00000008331
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------VFA-GEHVLTFAACTGNEDIM
RILLE---NHVPVHAQDSLGNT-----VLHVLVLQPNKN---------------------
--------QACA---------MHQLLLSCDR--SGAAAALEA------------------
------VQNHDGLTPIKMAAANGNTV-----------MFQNLVTR--------------R
R-AVQW------VFGSVTSSI-----YDLSGIDSWDD-----------------------
----------EQSVIELIAS-SRRRE----------------------------------
------------------------------------------------------------
------ARRILDITPVKELVSLKWSLYGRRYFWLWALIYMCY------IVIFTLCCIYRP
----LELY-AD--YNASSATLQ-PPSLGDFVMVQRPLAACYDSYD-DFLRLSGEIVVVVG
AVMMLVFEVRDMIRTGVK--RYFGSTVTGGPFHII------------MICYSCLVMLLLL
MRLTNTHGEYVPMAVALVLGWCNTMFFARGFEMLGPFTIMIQK-----------------
-------------MLFGDLLRFCWLMLMVLLGYAS---AFHICFQLLR------------
----RED------------------FLHFAG------FETVLFTMFQLFLGLLDIP----
---IPYDKQVPIIIKLVYVSYMIFAFLLMVNLLIAM-MGDTHWRVAHERDELWRAQVRVV
SV----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------
>Japanese_Lamprey_JL9656
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MCY------IVVFTLCCIYRP
----LDLR-AD--YNASLATLQ-PPGLGDFVMEQRPLAACYDSYD-DFLRLSGEIVVVVG
AVMMLVFEVRDMIRTGVK--RYFGSTVTGGPFHII------------MICYSCLVMLLLV
MRLTDTHGEYVPMAVALVLGWCNTMFFARGFEMLGPFTIMIQK-----------------
-------------MLFGDLLRFCWLMLLVLLGYAS---AFHICFQLLR------------
----RED------------------FLHFSG------FEMVLFTMFQLFLGLLDIP----
---IPYDKQVPIIIKLVYISYMIFAFLLMVNLLIAM-MGDTHWRVAHERDELWRAQVRGA
SV--------------PP------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------TGGH----------------------------
---------------------------------------------------
>Inshore_hagfish_ENSEBUG00000002114_TRPV6
-------MLALLAVRS--------------VVP-------GAVLRAVMHAV-------HG
TPA------------------------------------------------RAFSVD---
-----------ELNLLQ----------------------------------QQS------
FREV-----------------------------------------P----------L---
-----LGAAKDDDAETIYRLLRD---------------------------------PSCD
SGVL------------------GA--LGETALHVACLY---DNIEAATALLQGASH----
---------------------------------------LINEPMRAELY----------
---------------------------EG--------------------------QTALH
IAIANQNLNLVRELVIHGADVVRPRATGTFFQRDPHRPTCYY-GEYVLSFAACMGNEDIV
RFLLE---NGTPIHAQDSLGNT-----VLHVLVLQPNKT---------------------
--------TACQ---------MHDLLLSADR--SGVAASLVD------------------
------IANRAGLTPLKLAATEGNAV-----------MFQHLVSK--------------R
R-QVQW------SYGTVTSAI-----YDLMGIDSWDE-----------------------
----------ELSAIELITS-SRKRE----------------------------------
------------------------------------------------------------
------ARRLLEITPVKELVHLKWSHYGRFYFRLWFMAYMAY------IITFTLCCIHRP
----LAPR-VL--YNDT------DPQ-DNMVFVQRPLKECYLSHR-DYLRLVGELVSVLG
AVIILLFEVPDMVHMGVK--HYFGNTVTGGPFHII------------MTCYAWLVLVLMV
MRLTSTSGEYIPMSVALILGWCNTMFFARGSQMLGPFTIMIQK-----------------
-------------MIFGDLLRFCWLMLMVLMGFSS---AFHMSFQMLR------------
----AED------------------FPQFDG------LAMVIFTMFQLFLGLLDIP----
---IPYNKSNPSIIKVFYLAYMVFGFLLMVNLLIAM-MGDTHWRVAHERDELWRAQVAAT
TILLERRL--------PR-----------CLWPR-LGIYGKDFGLD--------------
----------------HKWYI-----RVEDRNDNMAQKIKRYARAFHDSVKK--------
------------------AE-----------------AEEGTSGAL--------------
-------------------------------------------------SLEAP------
-------------------SPSAIRTSARGWK-----------------ILRKTTM----
-------------AACSSESATSDPAEIVYHV-------------------
>Nanorana_parkeri_XP_018409299.1
---------------------------------------------MLHQVT-------QG
IRT-WTMNR------------------------------------------QLLDEE---
-----------RIELVQ----------------------------------WKR------
IHEV-----------------------------------------P----------L---
-----LRAAKENDIRLLKELLED---------------------------------EKFD
PFQR------------------GA--EGETALHVAVQH---ENLEAVEVLLDEAPE----
---------------------------------------LINQPMNSNLY----------
---------------------------RG--------------------------QTALH
IAAVNQNVNLVVTLIRRGADVKSPRATGSFFALNPKN-LFYF-GEHILTFAACVGDTEIV
KLLLD---NGADLWAQDCWGNT-----ALHVLVLQPNKS---------------------
--------LSCQ---------MFDFLLSQDR--EPHVKLLHE------------------
------IANRQGLTPLKLSAVEGNVV-----------MFQHLIQR--------------K
R-QTQW------TFGPVTTVL-----YDMSELDTWEG-----------------------
-----------QSILELIAS-SNKSQ----------------------------------
------------------------------------------------------------
------AHKILNISPMKELLQKKWQKTGRPYIWILAIVYMLY------MVCVSLCCANRP
----IKPR-ED---NVT------DPM-DITLYVQKTLQEAYVTPA-DHLRLIGEIISVIG
ACALLLTEVSLVYKAGAR--CFISHTLWKDPFHLI------------RISFSCLILVVLI
MRLTNTDGEVVSMSAALVFGWCYVMYFARGFQMVGPFTIMIQK-----------------
-------------MAASDLLKFCWLMAVVVVGYST---ALYIIFQPVN------------
----QTA------------------LGAFYP------YMISLESTYQLFLNILNGP----
---ANYDVDVPEMYILLYGSFCVIAFLLMFNLLIAM-MGDTQATMAKKKEELWKAQITAT
TVAMEQRF--------PK---------NWCFGSR-----PNEHDLE--------------
----------------ERHYL-----IVEERR----------------------------
-WHPFQP-----------HETSDS-------------SEESDEDTAPQNP----------
-------------------------------------------------VEDDPEDG---
-----LEPARAEIPDGMTTEEELEQSEECTWE----------------------------
--------------------------EEIYRL-------------------
>Xenopus_laevis_XP_018080412.1
-------MGGNKIQG-----------------GGDKDTD-LGIKQTLLSVM-------KK
KSK-WPESE------------------------------------------EILEPT---
-----------KEKFMRRSNCRPSPRNPAANPDTQN--------------LQKRKVGANM
LHEL-----------------------------------------P----------L---
-----LLAAKENDSERLKELLVN---------------------------------DRCD
PLQR------------------GA--LGETALHVAVQH---NNMEAAQILIREAPG----
---------------------------------------LINQPMTSDFY----------
---------------------------QG--------------------------QTALH
IATVNQSFSLVQLLIESGADVSSPRATGTFFSLSPKN-LFYF-GEHILVFAACVGNADIV
KLLID---RGADLHAQDCWGNT-----VLHILVLQPSKN---------------------
--------LSCQ---------MFDFILSQER--RDTEQPLYQ------------------
------IPNKQGLTPLKLAAAEGNIT-----------MFQHLVQK--------------Q
R-KAQW------AFGPVTTML-----YDVSEIDSWKT-----------------------
----------DQSVLEVIAT-ARKSQ----------------------------------
------------------------------------------------------------
------PFNILNCQPSKELLKKKWKRCGRPYLWSLAALYILY------MICVSLCCANRP
----LKPR-LD---NAT------DPR-DITLYIQKTLEESYITEE-DHLRLVGEIITVIG
AIVLLLLEISQVLRVGLK--FFACHQMWENPLHVM------------RISFSFLVLVTLV
LRLTNTDGEVIPMSMALVSGWCYIMYFAQGFQMLGPFTIIIQK-----------------
-------------MAASDLLKFCWLMAVVICGYSM---AFYIVFQTVD------------
----PVA------------------LGAFTP------FPVSLVSTYQLFLNILNGP----
---ANYDVDLPFMYIVLYSSFCVIAFLLMFNLLIAM-MGDTQAAMAKQKDELWRAQIAGT
TVMMEHRI--------PK-----------CLWSS---CTPTDQDLD--------------
----------------GRRYL-----SVEERR----------------------------
-WLPLLPAEL-----NRDQE--D--------------SDETD------------------
------------------------------------------------------------
--------------------TDDEDRNINSWVETGGSHLIPGANDSIR-ILPQGEH----
------WL----------------ASEEVYHI-------------------
>Coelancanth_TRPV5_XM_014491642
-------MGI--------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
IQEN-----------------------------------------P----------L---
-----FQAAKDNDIRAMKKILTC---------------------------------PCTD
IYKR--------------------------------------------------------
------------------------------------------------------------
---------------------------AG--------------------------QTALH
IAVVKQNMNLVKEMIKKGADVVTPRATGAYFRRSRRN-LIYF-GKXILSFAACTGNEEIV
RLLIE---HGANIRAQDYLGNT-----VLHILVLQPNKT---------------------
--------IACQ---------LFDMIMSYDQ--GENGVTTDM------------------
------IPNHKGLTPFKLAAMEGNVV-----------IFQHLIQK--------------K
K-RVQW------CFGPVTSTI-----YDLSGIDSWGD-----------------------
----------DLSVLELVVC-SQKKE----------------------------------
------------------------------------------------------------
-------------------VR---------------------------------------
--------------GHE----------QCSLWMILSLKECYLTRD-DQLRLVGEIITVIG
ALVILLLEIPDMLRIGPT--RFFGQTILGGPFHVI------------MILYAGLVLVILI
VRLTSSDGERVLMSFGLLLGWCNILYFARGFPMLGPFTIMIQK-----------------
-------------MIFGDLLRFCWLMLMVIFAYTS---AFHMTFQTQD------------
----PTS------------------APEFQD------YSMTLLTTFQLFLGLLDIP----
---INYEAYVPAIVKILYVSYMILAFLLMVNLLIAM-MGDTHWRVAHERDELWRAQ----
----QRTF--------PS-----------ATGPA---ECSFQNILF--------------
----------------TLFFFFFPPHRVEDRYDHAVQKIRRYAKAFRDQD----------
----------------RCRE-----------GKA---QEKEDPELQYQ------------
-------------------------------------------------NTFRP------
------------L-----GENEPPKESARGWQ-----------------ILRRTSM----
------TL--------LHKELKDAAQEEIYQVFMGITDADEGYPM------
>Elephant_shark_XM_007888808
-------MTSLMASSL------------------------------------------RR
LRAVWPETGTETGT-----------------------------------PGVGQQVQ---
-----------ELHVLQ----------------------------------QKR------
ISES-----------------------------------------P----------L---
-----LYAAKENMVQDIKKLIRC---------------------------------PSID
NFQT------------------GT--MGETALHIASTY---GNYQAVVTLLEAVPE----
---------------------------------------LINLPITGELY----------
---------------------------QG--------------------------ETSLH
IAVANGNVGLVRELIRRGADVVTPRATGTFFRLGGTG-ILYY-GEHVLSFAACVGNEEIV
RILIE---NGADIKAQDSLGNT-----VLHVLVLQQTQLP--------------------
--------VACQ---------IYDVLLSSEW--PQNEVRPDT------------------
------ILNRDGLSPLKLAAAEGNLQ-----------MFEHLVKK--------------Q
TCGMEP------FVRHRTSTY-----YNLSEIDSWDG-----------------------
----------DCSVLDLVIS-SHKTQ----------------------------------
------------------------------------------------------------
------ALKLLQVAPVQQLISLKWDKFGKCYFRLLSCTYLAY------IIIFTCCCVFRP
----LQLR-PD---NAT------DDR-DTTIYVEKPLRESYQTPG-DYVRLVGELISLFG
AIAILVIETHDILRYGPK--KYFGKSVLGGPFHVI------------NVSMAVLVLLVVL
LRLAGVVGQPEPMSLAVVLAWCNLMYFARGFQLLGPFSVMIQK-----------------
-------------IIFQIILPYLLLMFVVLFAFTC---GIYLSFQ-ED------------
----PDK------------------WERFSD------FSTTLFNIFMLFFGLVNMP----
---LNGKMQKPDMAQLLYTAYTLLAFALMVFLIIHV-MSELIRRLIRERDEIWRGQVAAT
TLLLERRL--------PR-----------CLWPR-LGICGTPYGLG--------------
----------------DSWFL-----RVGDGKD---------------------------
--TECCR-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------
>Elephant_shark_XM_007888807
-------MPGFLSGRGREIL--------------------SRFARELSCRL-------QP
GKE-LQDR-----------------------------------------------ID---
-----------KLHLLQ----------------------------------NQR------
ISET-----------------------------------------P----------L---
-----FLAARENDVDAVKTLLEC---------------------------------PTVD
LFEK------------------GV--MGETALHVAVLY---NNCEVATELLEAAPE----
---------------------------------------LINVPVTSQMY----------
---------------------------EG--------------------------ETALH
IAVANENVSLVRELIGRGADVVTARATGTFFRRNAKK-LFHF-GEHVLSFAACVGNEGIV
RILIE---NGADIKAQDSLGNT-----VLHHLVLQTQT----------------------
--------KVTE---------MFDLILSLE---PKDGATVET------------------
------MTNQAGLTPFKLAAQEGNVQ-----------LFQHLLRK--------------R
ERRLQW------FFQSVSTTF-----YDISGIDSWDD-----------------------
----------NCSVLDLVVF-SKEIE----------------------------------
------------------------------------------------------------
------ALKILDLHPIKELVSFKWNRYGKYYFRCLSVLYLLY------IIIFTLCCTFRP
----LIPR-PE---VVT------DPE-DTQLLVEAPLKLCYVSTK-DQVRLVGELISVFG
AIAILFIEISDMVRYGVS--GYFGKTVYGGPFHAI------------NICYACLVLLILV
LRLSSAGSEGIFMSLAMVLAWCNFIHFARGFQTLGTFSILIHK-----------------
-------------IVLENLMPYLFLMLIIIVGFTT---GLYVIFQELD------------
----PKK------------------WVYFDG------FKNEMFLMFMLFFGLLDIP----
---LNYEVYTPYMIKVLYVAYIMMTFQMMAILLINL-IAGTLRRVVPNRNRIYRAQVIAS
TLHLERRL--------PR-----------LLWPR-AGTWGEKVGLD--------------
----------------NSWYI-----WVEDRND---------------------------
----------------------KP------------------------------------
----------------------------------------------------AP------
------SNSRDL--------TTGESRAAGDWTRT-GRAVQPQA------DGRKRGL----
---------SPGTRPHGPRHRPTNHKSPGHHV------------------H
>Whale_shark_XM_020523124
-------MMGFLLGSGRWSV--------------------SALVNGLSVKL-------QP
RIA-QQER-----------------------------------------------ID---
-----------ELHVLQ----------------------------------HKR------
ILEV-----------------------------------------P----------L---
-----FTAARANDVSAIKKLLEC---------------------------------HSVD
PFEK------------------GV--MGETALHIAALY---GNHEVATMLLEEVPD----
---------------------------------------LINVPATSELY----------
---------------------------EG--------------------------KTALH
IAVANENVHLVKELINRGADVASSRATGIFFRRSEKN-LIYY-GEHVLSFAACVGNKEIV
QFLIE---NGADIKAQDYLGNT-----VLHHLVLHARH----------------------
--------YTAQ---------MYDFILSLD---PENGNPVEM------------------
------ITNNDGLTPFKLAALEGNVQ-----------LFQHLMRK--------------R
KRQIEW------FFKPISTSF-----YDLSGIDSWDD-----------------------
----------DRSVLDLVVC-SNEVE----------------------------------
------------------------------------------------------------
------ALKILNLPPIKALIHFKWNRYGKYYFRTIALLYFVY------IIIFTSCCIFRP
----LIPR-RD---NVT------DPR-DTQILEEAPLNLCYVSNE-DYIRLVGEIISVFG
AIAILLIESADILRYGTA--GYFGKTILGGPFHVI------------IICFAFLVLLILL
LRLTSAGAEGFCMALAIALAWCNSIYFFRGFRILGPFAILLQKIILEKFLTFVILMVMVL
IGFTTVGFEFLKRIILEKFLTFVILMVMVLIGFTT---ALHMSFQELD------------
----PSE------------------WIRFND------YKNLLFLMFMLFFGLLDIP----
---LNYEKYTPFMVKILYVAYIMMTFQLMAILFIFL-IAQTLRWVMKNCDVLWQAQITAS
MIHLERWL--------PK-----------YFWSR-AGICGLQLGLD--------------
----------------NSWYI-----WVEDTVDSDAQSCSS-------------------
--PKCGKVE------E-HQE--S--------------ANKAEKEQ---------------
------------------------------------------------------------
------SLPSEN--------ETEPNSS-VELH-----------------ILRRRSK----
------------------AHFSDVTSNEIKDA--------DCYL-------
>HUMAN06899_HOG_0033283_TRPV4
-------MADSSEGPRAGPGEVAELPGDESGTPGGEAFP----LSSLANLF-------EG
EDG-SLSPSP-----ADASR---PAGPGDGRPNLRMKFQGAFR------KGVPNPIDL--
----------LESTLYESSVV---P-GPKKAP-------------------MDS------
LFDYGTYRHHSSDNKRWRKKII-EKQPQSPKAPAPQPP-------PI-LKVFNRPIL---
-----FDIVSRGSTADLDGLLPFLLTHKK---------------------------RLTD
EEFRE-----------------PS--TGKTCLPKALLNLSNGRNDTIPVLLDIAER----
---------------------------------TGNMREFINSPFRDIYY----------
---------------------------RG--------------------------QTALH
IAIERRCKHYVELLVAQGADVHA-QARGRFFQPKDEGGYFYF-GELPLSLAACTNQPHIV
NYLTENPHKKADMRRQDSRGNT-----VLHALVAIADNTRENTK----------------
--------FVTK---------MYDLLLLKCAR-LFPDSNLEA------------------
------VLNNDGLSPLMMAAKTGKIG-----------IFQHIIRRE---VTDEDTRHLSR
K-FKDW------AYGPVYSSL-----YDLSSLDTCGE-----------------------
----------EASVLEILVY-NSKIE----------------------------------
-----------------------------------------------------------N
------RHEMLAVEPINELLRDKWRKFGAVSFYINVVSYLCA------MVIFTLTAYYQP
----LEGT---------------PPY-------------PYRTTV-DYLRLAGEVITLFT
GVLFFFTNIKDLFMKKC---PGVNSLFIDGSFQLL------------YFIYSVLVIVSAA
LYLAGIEAYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMIQK-----------------
-------------ILFKDLFRFLLVYLLFMIGYAS---ALVSLLNPCA------------
----NMK--VC------NEDQTNCTVPTYPSCRDSETFSTFLLDLFKLTIGMGDLE----
---MLSSTKYPVVFIILLVTYIILTFVLLLNMLIAL-MGETVGQVSKESKHIWKLQWATT
ILDIERSF--------PV-----------FLRK--AFRSGEMVTVGKSSDGTP-------
---------------DRRWCF-----RVDE-----------------------------V
NWSHWNQNL------GIINE--DP-------GKNET-YQYY-------------------
--------------------------------------------------------GFS-
-----HTVGRL---------------RRDRWS-----SVVPRVVELNK-NSNPDEVVVPL
DSMGNPRCDGHQQGYPR-----KWRTDDAPL--------------------
>Chicken_TRPV4_ENSGALG00000036360
-------MADPED------------PRDAGDVLGDDSFP----LSSLANLF-------EV
ED----TPSP-----AEPSRG--PPGAVDGKQNLRMKFHGAFR------KGPPKPMEL--
----------LESTIYESSVV---P-APKKAP-------------------MDS------
LFDYGTYRQHPSENKRWRRRVV-EKPVAGTKGPAPNPP-------PI-LKVFNRPIL---
-----FDIVSRGSPDGLEGLLSFLLTHKK---------------------------RLTD
EEFRE-----------------PS--TGKTCLPKALLNLSAGRNDTIPILLDIAEK----
---------------------------------TGNMREFINSPFRDVYY----------
---------------------------RG--------------------------QTALH
IAIERRCKHYVELLVEKGADVHA-QARGRFFQPKDEGGYFYF-GELPLSLAACTNQPHIV
HYLTENGHKQADLRRQDSRGNT-----VLHALVAIADNTRENTK----------------
--------FVTK---------MYDLLLIKCAK-LFPDTNLEA------------------
------LLNNDGLSPLMMAAKTGKIG-----------IFQHIIRRE---IADEDVRHLSR
K-FKDW------AYGPVYSSL-----YDLSSLDTCGE-----------------------
----------EVSVLEILVY-NSKIE----------------------------------
-----------------------------------------------------------N
------RHEMLAVEPINELLRDKWRKFGAVSFYISVVSYLCA------MIIFTLIAYYRP
----MEGP---------------PPY-------------PYTTTI-DYLRLAGEIITLLT
GILFFFSNIKDLFMKKC---PGVNSFFIDGSFQLL------------YFIYSVLVIVTAG
LYLGGVEAYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMIQK-----------------
-------------ILFKDLFRFLLVYLLFMIGYAS---ALVSLLNPCP------------
----SSE--SC------SEDHSNCTLPTYPSCRDSQTFSTFLLDLFKLTIGMGDLE----
---MLESAKYPGVFIILLVTYIILTFVLLLNMLIAL-MGETVGQVSKESKHIWKLQWATT
ILDIERSF--------PL-----------FLRR--VFRSGEMVTVGKGTDGTP-------
---------------DRRWCF-----RVDE-----------------------------V
NWSHWNQNL------GIISE--DP-------GKSDT-YQYY-------------------
--------------------------------------------------------GFS-
-----HTVGRL---------------RRDRWS-----TVVPRVVELNK-SCPTEDVVVPL
GTMGTAEARERRHG----------QTPSSPL--------------------
>Coelacanth_TRPV4_ENSLACG00000001362
-------MGDVEEQNKLNSSGDANDTRTEDGSQQNDAFP----LSSLANLF-------EN
EE----GATA-----TDTAKA--PQTAGDGKQNLRMKFHGAFK------KGMPNPMDL--
----------LESTIYESPVV---P-APKKAP-------------------MDS------
LFDYGTYHQYPTENKRRRKRIIHDKQSPNQKTQAPNPP-------PI-LKVFNRPIL---
-----FDIVSRGTAAELDGLLAFLVTHKK---------------------------RLAD
EEFRE-----------------PS--TGKTCLPKALLNLTNGKNDTIPILVEIAEK----
---------------------------------TGNLREFINSPFRDVYY----------
---------------------------RG--------------------------QTALH
IAIERRCKQYVELLVEKGADVHA-QARGRFFQPRDEGGYFYF-GELPLSLAACTNQPDIV
HYLIENAHKKADLRRQDSRGNT-----VLHALVAIADNTRENTK----------------
--------FVTK---------MYDMLLIKCAK-LFPECNLEA------------------
------ILNNDGMSPLMMAAKLGKIG-----------IFKYIIRRE---VMDENARHLSR
K-FKDW------AYGPVYSSL-----YDLSSLDTCGM-----------------------
----------EVSVLEILVY-NSRIE----------------------------------
-----------------------------------------------------------N
------RHEMLAVEPINELLRDKWRKFGAVSFYISVVSYLVA------MVIFTLIAYYRP
----VEGR---------------PPY-------------PYKTTI-DYLRLAGEVITLLT
GIFFFFTNIKDLFLKKC---PGVNSLLIDGSFQLL------------YFIYSVLVLVTAA
LYLTGIEAYVAVMVFALVLGWMNTLYFTRGLKLTGTYSIMLQK-----------------
-------------ILFKDLFRFLLVYVLFMIGYAS---ALVSLLNPCL------------
----TTE--TC------TANNASCTAPEYPYCRDSNTFGKFIMDLFKLTIGMGDLE----
---MVNSAKYPGVFIILLVTYIILTFVLLLNMLIAL-MGETVGQVSKESKQIWKLQWATT
ILDIERSF--------PV-----------FLRR--VFRSGEMVTVGKNLDGTP-------
---------------DRRWCF-----RVDE-----------------------------V
NWSHWNQNL------GIINE--DP-------GKNET-YQYY-------------------
--------------------------------------------------------GFS-
-----HTMGRL---------------RRDRWS-----TVVPRVVELNK-TPRADEVVVSL
DPMGMSNVHDTKRGDPH-----NWKKDETQI--------------------
>Elephant_shark_XM_007901853.1_TRPV4
-------MARPEGKDSGRVNNSSIENVEEEGPPASESFP----LSSLANLF-------EN
DE----SNST-----LEVSRGALRENGESNKQNLRAKFHGAFK------NRMPNPMDL--
----------LESSIYDSSIPSMAP-APKKAP-------------------MDS------
LFDYGTYRQ-SSDEKRKRKKLP-KDKAPKVKPPAPDPP-------PV-LKVFNRVLL---
-----FDIVSRGVVSELDGLLSFLLSQKK---------------------------RLTD
EEFRE-----------------PS--TGKTCLPKALLNLNNGKNDAIPVLLEIAEK----
---------------------------------TGNLREFINAPFRDVYY----------
---------------------------RG--------------------------QIALH
IAIERRCKHYVELLVEKEVDVHA-QARGKFFQPKDEGGYFYF-GELPLSLAACTNQPDIV
HYLTENPHKVADLRRQDSRGNT-----VLHALVAIADNTRENTK----------------
--------FLTK---------MYDLLLIKCAK-LYPDCNLEV------------------
------ILNNDGLSPLKMAAKLGKIG-----------IFQHIIRRE---IKDESARHFSR
K-FRDW------AYGPVSSSL-----YDLSAIDTCGE-----------------------
----------EVSLLEILVY-NGKIE----------------------------------
-----------------------------------------------------------N
------RYEMLAVEPINELLRDKWKKFAAVSFYLSVISYLTA------MVIFTLIAYYRP
----SDGK---------------PPY-------------PYNTTA-DFMRMGGEIITVVT
AIFFFFTNVKDLFLKKC---PGVNSMFIDGSFQLL------------YFIYSILVLVSAG
LYLAGEESYLGVMVFALVLGWINTMYFTRGLKLTGTYSIMIQK-----------------
-------------ILVKDLFRFLLVYLLFMIGFTS---ALVSLLVTCP------------
--INEFE--ICDI----TSDSPNCTSSTYPICRDNLSFSKFLLELFRLTIGMGDLD----
---VINSAKFPIVFVILLVSYIILTFVLLLNMLIAL-MGETVGQVSKKSKQIWKLQWATT
ILDVERSF--------PI-----------CLRK--AFRSGEMVTVGINSDGTP-------
---------------DRRWCF-----RVDE-----------------------------V
NWSHWNQNV------GIINE--DP-------GRNDI-YQFD-------------------
-----------------------------------------------------G--GIN-
-----QTMGRL---------------RRDRWS-----TVVPRVVELNK-PSRADEYVVGM
EHISMDHPRERKYGYGQSQRNIHWKRAESHI--------------------
>HUMAN11617_HOG_0033282_3a_1a_TRPV2
-------MTSPSSSPV---------------------------------------FRLET
LDG-GQEDGSE----------------------------ADRGKLDF--GSGLPPME---
-------------SQFQGEDR-------KFAPQIRV------------------------
-------------NLNYRKGTG---------ASQPD---------P---NRFDRDRL---
-----FNAVSRGVPEDLAGLPEYLSKTSK---------------------------YLTD
SEYTE-----------------GS--TGKTCLMKAVLNLKDGVNACILPLLQIDRD----
---------------------------------SGNPQPLVNAQCTDDYY----------
---------------------------RG--------------------------HSALH
IAIEKRSLQCVKLLVENGANVHA-RACGRFFQKGQGT-CFYF-GELPLSLAACTKQWDVV
SYLLENPHQPASLQATDSQGNT-----VLHALVMISDNSAENIA----------------
--------LVTS---------MYDGLLQAGAR-LCPTVQLED------------------
------IRNLQDLTPLKLAAKEGKIE-----------IFRHILQRE---FSG--LSHLSR
K-FTEW------CYGPVRVSL-----YDLASVDSC-E-----------------------
----------ENSVLEIIAF-HCKSP----------------------------------
-----------------------------------------------------------H
------RHRMVVLEPLNKLLQAKWDLLIPK-FFLNFLCNLIY------MFIFTAVAYHQP
----TLKK-QA------------APH-------------LKAEVG-NSMLLTGHILILLG
GIYLLVGQLWYFWRRH----VFIWISFIDSYFEIL------------FLFQALLTVVSQV
LCFLAIEWYLPLLVSALVLGWLNLLYYTRGFQHTGIYSVMIQK-----------------
-------------VILRDLLRFLLIYLVFLFGFAV---ALVSLSQEAWR-------PEAP
TGPNATE---SVQPMEGQEDEGN--GAQYRG------ILEASLELFKFTIGMGELA----
---FQEQLHFRGMVLLLLLAYVLLTYILLLNMLIAL-MSETVNSVATDSWSIWKLQKAIS
VLEMENGY--------WW-----------C-RK--KQRAGVMLTVGTKPDGSP-------
---------------DERWCF-----RVEE-----------------------------V
NWASWEQTL------PTLCE--DPSG----AGVPRT-LE-N-------------------
-----------------------------------------------------P--VLA-
-----SPPKED--------------EDGASEEN---YVPVQLLQSN--------------
---------------------------------------------------
>Chicken_TRPV2_ENSGALG00000004519
-------MDNFTNDQSG-----------------------PCQRNRLVGLL-------ET
DDS-IQEDKP--------------------TSSTKEERSGQYGK-----KGEPRPLE---
-------------SPYQKESS-------DYSPKVMI------------------------
-------------NLNYRPGFV---------SNQKD---------P---NRFDRDRL---
-----FSAVSRGSPEALDGLLEYLRRTSK---------------------------FLTN
SEYTD-----------------AK--TGKTCLMKALLNLKNGRNDTIPVLLEIDQK----
---------------------------------TQNPRPLVNVACSDCYY----------
---------------------------RG--------------------------QTALH
IAIEKRSLDLVKVLVEHGADVHA-RAHGEFFRKKKEGVCFYF-GELPLSLAACTNQFEVV
EYLLNNPHQKARLQEQDTQGNT-----VLHALVMIADDTEENTK----------------
--------FVST---------VYVEILKAGVK-TDPTVKLEE------------------
------IVNYDGLNPLQLAAKTGKVE-----------IFRHIIQRE---IKDPVYRHLSR
K-FTEW------TYGPIHVSL-----YDLSSLDSF-E-----------------------
----------ENSVLEILAY-SSDTP----------------------------------
-----------------------------------------------------------N
------RYKMVVLEPLNKLLQQKWETFASKRFYFSFISYLSF------MIIFTAIAYYQP
----LRVK---------------PSF-P-----------VEFTAG-GFLWVSGLIIILLG
GVYLIFAQSLYLRRRR----QSLKTMCSDSCVEIL------------IFIQAFSLLLSAV
LYGASSENYVAVMVFSLLLGWVNMLYYTRGFQRIGIYSVMIQK-----------------
-------------TILRDLLRFLLVYIIFLFGFAA---ALVTLMGDAPSL---SQNKSVA
QMENAGS------------------HAMYGG------LLSVCLELFKITIGMGDLD----
---FHEHARFRYFVMLLLLLFVILTYILLLNMLIAL-MSETVTDISGYSKSVWKLQRAIA
ILEIEKAW--------LW-------------RQGGKRRSGCLMSVGLN---KK-------
---------------DERWCF-----RVEE-----------------------------I
KWTSWAKEV------GVLKE--EP-------GNTND-LEIN-------------------
-----------------------------------------------------P------
--------------------------EGKVK-----------------------------
---------------------------------------------------
>HUMAN11287_HOG_0033282_3a_1b_TRPV1
-------MKKWSSTDLG-----------------------------------------AA
ADP-LQKDTCPDPLDGDPNSRPPPAKPQLSTAKSRTRL---FGKGD---SEEAFPVD---
-------------CPHEEGELDSCP-TITVSP-VITIQRPGDGPTGARLLSQDS------
VAAS--------TEKTLR--------------------------------LYDRRSI---
-----FEAVAQNNCQDLESLLLFLQKSKK---------------------------HLTD
NEFKD-----------------PE--TGKTCLLKAMLNLHDGQNTTIPLLLEIARQ----
---------------------------------TDSLKELVNASYTDSYY----------
---------------------------KG--------------------------QTALH
IAIERRNMALVTLLVENGADVQA-AAHGDFFKKTKGRPGFYF-GELPLSLAACTNQLGIV
KFLLQNSWQTADISARDSVGNT-----VLHALVEVADNTADNTK----------------
--------FVTS---------MYNEILMLGAK-LHPTLKLEE------------------
------LTNKKGMTPLALAAGTGKIGVIENGPPLSFMVLAYILQRE---IQEPECRHLSR
K-FTEW------AYGPVHSSL-----YDLSCIDTC-E-----------------------
----------KNSVLEVIAYSSSETP----------------------------------
-----------------------------------------------------------N
------RHDMLLVEPLNRLLQDKWDRFVKRIFYFNFLVYCLY------MIIFTMAAYYRP
----VDGL---------------PPF-------------KMEKTG-DYFRVTGEILSVLG
GVYFFFRGIQYFLQRR----PSMKTLFVDSYSEML------------FFLQSLFMLATVV
LYFSHLKEYVASMVFSLALGWTNMLYYTRGFQQMGIYAVMIEK-----------------
-------------MILRDLCRFMFVYIVFLFGFST---AVVTLIEDGK------------
NDSLPSE--STSHRWRGPACRPP--DSSYNS------LYSTCLELFKFTIGMGDLE----
---FTENYDFKAVFIILLLAYVILTYILLLNMLIAL-MGETVNKIAQESKNIWKLQRAIT
ILDTEKSF--------LK-----------CMRK--AFRSGKLLQVGYTPDGKD-------
---------------DYRWCF-----RVDE-----------------------------V
NWTTWNTNV------GIINE--DP-------GNCEG-VKRT-------------------
-----------------------------------------------------L--SFS-
-----LRSSRV---------------SGRHWKN---FALVPLLREASA-RDRQSAQPEEV
YL--------------RQ-FSGSLKPEDAEVF-------KS--PAASG-EK
>Chicken_TRPV1_ENSGALG00000004649
MSSILEKMKKFGSSDIEESEVT------DEHTDGEDSAL-------------------ET
ADN-LQGTFS--------------NKVQPSKSNIFARR-GRFVMGDC--DKDMAPMD---
-------------SFYQMDHL--------MAPSVIKFHANMERGKLHKLLSTDS------
ITGC--------SEKAFK--------------------------------FYDRRRI---
-----FDAVARGSTKDLDDLLLYLNRTLK---------------------------HLTD
DEFKE-----------------PE--TGKTCLLKAMLNLHDGKNDTIPLLLDIAKK----
---------------------------------TGTLKEFVNAEYTDNYY----------
---------------------------KG--------------------------QTALH
IAIERRNMYLVKLLVQNGADVHA-RACGEFFRKIKGKPGFYF-GELPLSLAACTNQLCIV
KFLLENPYQAADIAAEDSMGNM-----VLHTLVEIADNTKDNTK----------------
--------FVTK---------MYNNILILGAK-INPILKLEE------------------
------LTNKKGLTPLTLAAKTGKIG-----------IFAYILRRE---IKDPECRHLSR
K-FTEW------AYGPVHSSL-----YDLSCIDTC-E-----------------------
----------KNSVLEIIAY-SSETP----------------------------------
-----------------------------------------------------------N
------RHEMLLVEPLNRLLQDKWDRFVKHLFYFNFFVYAIH------ISILTTAAYYRP
----VQKG-DK------------PPF-A-----------FGHSTG-EYFRVTGEILSVLG
GLYFFFRGIQYFVQRR----PSLKTLIVDSYSEVL------------FFVHSLLLLSSVV
LYFCGQELYVASMVFSLALGWANMLYYTRGFQQMGIYSVMIAK-----------------
-------------MILRDLCRFMFVYLVFLLGFST---AVVTLIEDDN----------EG
QDTNSSEYARCSHTKRG--------RTSYNS------LYYTCLELFKFTIGMGDLE----
---FTENYRFKSVFVILLVLYVILTYILLLNMLIAL-MGETVSKIAQESKSIWKLQRAIT
ILDIENSY--------LN-----------CLRR--SFRSGKRVLVGITPDGQD-------
---------------DYRWCF-----RVDE-----------------------------V
NWSTWNTNL------GIINE--DP-------G-CSGDLKRN-------------------
-----------------------------------------------------P--SYC-
-----IKPGRV---------------SGKNWK-----TLVPLLRDGSR-REETPKLPEEI
KL--------------KPILEPYYEPEDCETL-------KESLPKSV----
>Elephant_shark_XM_007896535.1_TRPV1
-------MRRMDNEDPSEATETTTVNADTDHVFTED----------------------ES
SDN-AL---------GHESGGEVWEIPHGFKAMKRTAHRYHFGLREFEGSKTKVPMD---
-------------SFYSIDYQ--------LSP------------KDSRFGSQDS------
VWSG--------KNQAFRPPV----------SSETDSS-------P---SIYNRHWL---
-----FEMVSKGTAKELDGFEEHLMRNKK---------------------------YLTD
WEYKD-----------------PE--TGKTALLKALLNLNNKKNDTVSRLLEIAEK----
---------------------------------GNNLKEFINAAYTDSYY----------
---------------------------RG--------------------------QTALH
VAIERRSAHFVELLVRNGADVHA-RASGIFFKQKKSGDGFYF-GELPLSLAACTNQLDIV
TFLLENPHSRADVSAVDSRGNN-----VLHALVAVADNTPENTK----------------
--------FVTK---------MYNGLLMKSVK-IRPLENLEA------------------
------TTNKKGLTPLKLAAKTGKLQ-----------LFKDIMGRE---VQEEECRHLSR
K-FTEW------AYGPVHSSL-----YDLSSLDTD-D-----------------------
----------EQSVLEIIVH-GTKNE----------------------------------
-----------------------------------------------------------F
------RHEMLLVEPLNKLLQEKWNKFARFIFCVDFFIYFAY------MTVFTLVGYNRK
----EN---MT------------LPF-P-----------IEHTTE-GYLRLTGQIITLLG
AFYLFFTGIHTVIFRRMFRGKSVKPITVDSYCDIL------------SFVQSLMLLASAL
LYTTGRNEYVGFMVIAMALGWINTLYYSRGFYRMGVYSVMVQK-----------------
-------------ILVTDILRFLIVYIVFLFGFGV---ALVTLIEEGPPKGRMATSQKNY
RLLSKTE-CVC--------------DSGYNTYKD---LYSTFLELFRFTIGMGDLE----
---FTEDYKFKEVFILLLISYVILTYILLLNLLIAL-MSQTVEKISKDSKNIWKLQRAVT
ILDLERSL--------PR-----------CLRD--RLRSGESVVVGMTPDNKE-------
---------------DMRRCY-----RIDE-----------------------------V
NWTKWNTNL------GLINE--DP-------GNSNV-IRRS-------------------
------------------------------------------------------------
------SLARN----------SRFRRGESGWQ-----SMLPLLREMKT------------
------------------EKQEEIESHEMDTLTGRRRRKLSVTPKDV----
>HUMAN11284_HOG_0033282_3b_TRPV3
MKAHPKEMVPLMGKRVAAPSGNP--AILPEKRPAEITPT----KKSAHFFLEIEGF--EP
NPT-VAKTSP-------------PVFSKPMDSNIRQCI-----------SGNCDDMD---
------------------------------SP--QSP--------------QDD------
VTET---------------------------PSNPNSPSAQLAK-E--EQRRKKRRLKKR
----IFAAVSEGCVEELVELLVELQELCRRRHDEDVPDF--------------LMHKLTA
S----------------------D--TGKTCLMKALLNINPNTKEIVRILLAFAEE----
---------------------------------NDILGRFINAEYTEEAY----------
---------------------------EG--------------------------QTALN
IAIERRQGDIAALLIAAGADVNA-HAKGAFFNPKYQHEGFYF-GETPLALAACTNQPEIV
QLLME--HEQTDITSRDSRGNN-----ILHALVTVAEDFKTQND----------------
--------FVKR---------MYDMILLRSGN-W----ELET------------------
------TRNNDGLTPLQLAAKMGKAE-----------ILKYILSRE---IKEKRLRSLSR
K-FTDW------AYGPVSSSL-----YDLTNVDTT-T-----------------------
----------DNSVLEITVY-NTNID----------------------------------
-----------------------------------------------------------N
------RHEMLTLEPLHTLLHMKWKKFAKHMFFLSFCFYFFY------NITLTLVSYYRP
----REEE-A-------------IPH-P-----------LALTHKMGWLQLLGRMFVLIW
AMCISVKEGIAIFLLRP---SDLQSILSDAWFHFV------------FFIQAVLVILSVF
LYLFAYKEYLACLVLAMALGWANMLYYTRGFQSMGMYSVMIQK-----------------
-------------VILHDVLKFLFVYIVFLLGFGV---ALASLIEKCP------------
--KDNKD------------------CSSYGS------FSDAVLELFKLTIGLGDLN----
---IQQNSKYPILFLFLLITYVILTFVLLLNMLIAL-MGETVENVSKESERIWRLQRART
ILEFEKML--------PE-----------WLRS--RFRMGELCKVAED------------
---------------DFRLCL-----RINE-----------------------------V
KWTEWKTHV------SFLNE--DP-------G----------------------------
-----------------------------------------------------P-VRRT-
-----ADFNKI------------QDSS----------------------RNNSKTTLNAF
--------------------------EEVEEF-----------PETSV---
>Chicken_TRPV3_ENSGALG00000004660
MIKDNKEVVPLMGKKTNPPGAPP--SNQQEKKPTESTPT----KKSSHFFLEIEGF--ES
NAT-PNNTSP-------------PVFSKPMDSNIRPCA-----------SANGEDMD---
------------------------------SP--QSL--------------QDD------
VTEY---------------------------SPNVDSCGANIAQGP--EQTGARKKLKKY
----IFRAVSEGNVEELQGLLAELKERSNVCTNMTVPDY--------------LMKKFTA
S----------------------D--TGKTCLMKALLNINNNTNQIVNMLLSFAEE----
---------------------------------NGILERFINAAYTEEAY----------
---------------------------RG--------------------------QTALN
IAIERRQFEITQTLIEKGADVNA-HAQGIFFNPKHKHEGFYF-GETALALAACTNQPDII
ELLMD--NTRTNIAAQDSRGNN-----ILHALVTVAEDFKTQND----------------
--------FVIR---------MYDMILLKSKD-R----NLEK------------------
------VKNKEGLTPLQLAAKTGKLE-----------VLKYILSRE---IRDKPNRSLSR
K-FTDW------AYGPVQSSL-----YDLTELDTT-A-----------------------
----------DNSVLEIIVY-NTNIG----------------------------------
-----------------------------------------------------------N
------RHEMLTLEPLNSLLRMKWKRFARHMLFMSCCFYFLY------NVTLTLVSYHRP
----NENE-A-------------PPY-P-----------LALTRGVGWLQLSGQVMVMLG
AIFLAIKESVAIFLLRP---SDLQSILSDAWFHFA------------FFIQAMLVIFSVF
LYLSSYKEHLVCLVLAMALGWANMLYFTRGFQSMGIYSVMIQK-----------------
-------------VILNDVIKFLVVYIVFLLGFGV---ALAALIETCQ------------
---NGGE------------------CLSNSS------LGPVLMDLFKLTLGLGDLE----
---IQQNSKYPVLFLLLLITYVVLTFVLLLNMLIAL-MGETVEDISKESEHIWKLQRART
ILEFEKFL--------PK-----------SLRK--KFQLGERCKVAEN------------
---------------DTRVCL-----RINE-----------------------------V
RWTEWKTHV------SFINE--DP-------G----------------------------
-----------------------------------------------------P------
-----TDPSKV------------QDNS----------------------RTNSKNTLNTF
--------------------------EETDDL-----------PETSL---
>Coelacanth_TRPV3_XM_006010802.2
-------MG---------------------------------------------------
------------------------------------------------------------
------------------------------LPNL-----------------QTK------
VT-------------------------------------------P--KGIYCHRGL---
-----PAAVIQN------------------------------------------GRGLSD
GHSRVFSISHQVKSIFIYKALNNE--NGKTCLMKALLNMNDKTRQIVTQMLSFAED----
---------------------------------RGFQKELVNAEFTSKYY----------
---------------------------KG--------------------------QTALH
IAIERRHEDIVKLLIQKGADVNV-KANGEFFRNKETG--FYF-GETPLALAVCTKQKSIV
DLLLD--HEEINLKETDQWGNT-----VLHALVSMVDDSEDH------------------
--------YLEA---------VYKAILEKYSE-KYRKETLEH------------------
------KTNGENLTPVQLAAKLGKRK-----------ILEYILSRE---LKDEKTLHLSR
K-LTDW------VYGPLCSSL-----YDLNDLDTS-K-----------------------
----------KNSVLHLIVY-NSKLS----------------------------------
-----------------------------------------------------------N
------RHEMLEFELLKTLLNEKWKKFVSHMFYIGLFIYFIY------NVILTLVSYYRP
----YEDK---------------FPA-P-----------LDLSGDIGRLYLTGQVFVFIC
AIYLMLKEKLVLSEW-----ADLKSFLSDEWFRIS------------FWLQAMLVILSSI
IYWIGLREYLILLVLAMSLGWTNMLYYTRGFQSLGIYSVMIQK-----------------
-------------VILNDVLKFLLIYVLFLLGYGV---ALASLVKVCS------------
---DENE------------------CSPYSS------FQSTVLELFKLTLGLGDLE----
---LQKHSLYPELFLALLVLYVLLTF------------------------------RART
ILNLEGSLLKFPRKLRPE-----------FLSK--RLEMGEVFKLFDT------------
---------------DKR-YF-----RLND-----------------------------L
DWDVFNKKI------TRINE--DP-------G----------------------------
------------------------------------------------------------
--------------------------------------------------KNQKLVLWNF
THLVY--------------REFQVPTEKMSEV-----------PE------
>Elephant_shark_XM_007896537.1_TRPV3
-------MIKFRA-----------------------------------------------
-------------------------------------------------RRELRMMD---
---------------------------------------------------KNL--RVLL
ATEV--------------------------DSCTPD---------PCNEMKIKQRKLQNR
VWVDFYRSIAEGDLGEFDKFLQLFQESKT---------------------------KLTA
EWLRD-----------------PR--TGKTCLMKALLNLNDNTQEMVEKLISFAEA----
---------------------------------SDSLEQLINAEYTDREY----------
---------------------------KG--------------------------QTALH
IAIERRCKTIVQLLVEKGADINA-KAQGRFFKPKKLKHGFYF-GELPLSLAACTNQPDIV
TLLMA--SGRTDVRAQDAWGNC-----ILHALVTVADDSEDNTT----------------
--------FVTE---------MYDMILMSSQD-H----NLEG------------------
------ICNLRGLNPLQLAAKLGKFK-----------IFSHILCRE---FKDKKHLNLSR
K-ITDW------AYGPVSSSL-----YDITEVDTN-H-----------------------
----------QNSVLEIVVH-NTKIQ----------------------------------
-----------------------------------------------------------N
------RHELLSVEPLNTLLEEKWLTFGAHMFTITCIVYVLY------IIGFTTVYYNQA
----ERYQ-SL------------ISE-N-----------LTSTTS---LQLFGEISSFTA
AWVVIIKEGLVLVRLRP---SDLRSIVTDAWFHIL------------FFLQALMTASSAV
LCWARVEAHLLLLVPALALGWINILYFTRGFKSMGIYSVILQK-----------------
-------------VLLTDVLLFLFVYLLFLIGFSV---ALASLIDSCP------------
---NSLE------------------CSPYLT------FNTVILELFKLTLGLGDLQ----
---IQQHAKYPQLFLLLLGVYVVLTFVLLLNMLIAL-MSETVEDTAKESKNIWKLQRARM
ILNLERSL--------PK-----------CLRR--RFQLGTILKNSQG------------
---------------HSRRYI-----RINE-----------------------------V
NWTKWKTSV------ARIHE--DP-------GNEE--EEQEDKSSDEVE-----------
-------------------------------------------------HKICP----G-
-----TTLQSVQ--------TTSGPSDSEKEE--------PRCKRIGKLRIKAKNM----
----------------NTLHSEAVLEQETYPL-----------QEPSNTTQ
>HUMAN26704_HOG_0033284_Homo_sapiens_A1
-------MKRSL------------RKMWRPGEKKEPQGV-------VYEDVP------DD
TED-FKES------LKVVFEGSAYGLQNFNK------------------QKKLKRCDDMD
TFFLHYAAAEGQIELME----------------KIT---------------RDSSLEVLH
EMDD----------------------------------YGN---TP----------L---
-----HCAVEKNQIESVKFLLSRGANPNLRNFNMMAPLHIAVQGMNNEVMKVLLEHRTID
VNLE------------------GE--NGNTAVIIACTT---NNSEALQILLKKGAKPCKS
NKWGCFPIHQAAFSGSKECMEIILRFGEEHGYSRQLHINFMNNGKATPLHLAVQNGDLEM
IKMCLDNGAQIDPVEKGRCTAIHFAATQGATEIVKLMISSYSGSVDIVNTTDGCHETMLH
RASLFDHHELADYLISVGADINKIDSE----------------GRSPLILATASASWNIV
NLLLS---KGAQVDIKDNFGRN-----FLHLTVQQPYGLKNLRPEFMQMQQIKELVMDED
NDGCTPLHYACRQGGPGSVNNLLGFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQDIS
DTRLLNEGDLHGMTPLHLAAKNGHDK-----------VVQLLLKKGALFLSD--------
--HNGWTALHHASMGGYTQTMKVILDTNLKCTDRLDEDGNTALHFAAREGHAKAVALLLS
HNADIVLNKQQASFLHLALH-NKRKEVVLTIIRSKRWDECLKIFSHNSPGNKCPITEMIE
YLPECMKVLLDFCMLHSTEDKSCRDYYIEYNFKYLQCPLEFTKKTP-TQDVIYEPLTALN
AMVQNNRIELLNHPVCKEYLLMKWLAYGFRAHMMNLGSYCLG------LIPMTILVVNIK
---------PGMAFNSTGIINETSDH-----------SEILDTTN-SYLIKTCMILVFLS
SIFGYCKEAGQIFQQKRN--------------YFMDISNVLE----WIIYTTGIIFVLPL
FVEIPAHLQWQCGAIAVYFYWMNFLLYLQRFENCGIFIVMLEV-----------------
--------------ILKTLLRSTVVFIFLLLAFGL---SFYILLNLQD------------
---------------------------PFSS------PLLSIIQTFSMMLGDINYRESFL
EPYLRNELAHPVLSFAQLVSFTIFVPIVLMNLLIGLAVGDIAEVQKHASLKRIAMQVELH
T-SLEKKL--------PLWFLRKVDQKSTIVYPNKPRSGGMLFHIFCFLFCTG----EIR
QEIPNADKSLEMEILKQKYRLKDLTFLLEKQHELIKLIIQK-ME----------------
----------------IISETED--------------DDSHCSFQD--------------
------------------------------------------------------------
------RFKKEQ--------MEQRNSR---WN----------------------TVLRAV
KAKTHH---------------LEP---------------------------
>CHICK06280_HOG_0033284_Gallus_gallus_A1
-------MKRSL---------------WRLCQSREKAAT-----SSAYQGV-------VC
EAD-AASVASQD-VFKVISDGSACRLRSFIKKN----------------RSGLTKVDELN
ATPLHHAAEGGQIELMQ----------------LII---------------DDSSSEVLN
VMDS----------------------------------SGN---TP----------L---
-----HWATRKNQVESVRLLLSRGANPNILNSNMMAPLHMAIQSLHNEIVKILVQHSSTD
VNLE------------------GE--AGNTPIIVACYK---DNPEALTFLIENGGKICKP
NKTGCMPIHAAAFSGAKTCMEILLKKGEELGHSAKTHINFTNNGKCSPLHLAVQSGDLEM
IKMCIEFGAQIDLKQNEKCTALHFAATQGATEIVKLMMSSYAGDESIIDAVDGNKETLLH
RTALFDHYELAEYLISTGANIDSVDTE----------------GRSPLLLATSCASWKIV
NLLLS---KGANVSLKDHLGRN-----FLHLTVLQPGGLQHLNEKFLQMEHIKNLVVDED
NEGCTPLHYACRQGVALSVNNLLSLNVSIYSKSRDKKSPLHFAASYGRINTCQRLIRDMK
DTRLLNEGDKKGMTPLHLAAQNGHEK-----------VVQFLLKRGALFLCD--------
--YKGWTALHHAAFGGYTRTMQIILDTNVKCTDKVDEEGNTALHLAAKEGHAKAVRLLLD
YGAKILLNKAVASFFHEAIH-NRRKDVVSTVILHKRWEEAVLTFSHYSSANKCPLLEMIE
YLPDSFKLVLDNCIIESSEEKTSRDFYIEYNFRYLQCPLALNRKLKEAEDIFYEPLAILN
AMVRHNRMELLSHPVCKEYLLMKWMAYGFRAHLMNLGIYSLG------LIPLTLLVTHIQ
---------PGRPLNGTEIYEA-RPL----------------EYEDSYFTRVCMCLVLIM
SLLGICKEIFQLIQQKLK--------------YLLDYSNLLD----WTIYSTSIIFVSSL
FINTPAHLQWECGAIAVYLSWMNFLLYLQRFENYGIYVVMFWE-----------------
--------------ILRTLIRIAVVFFFLILAFGL---SFFVLLGSQQ------------
---------------------------TYST------PLLSVMKTFAMMLGDINYHDAFL
DPLLSSELPYPFLSYTVLIIFTLLIPILLMNLLIGLAVGDIAEVQKYAALKRIAMQVNLH
T-NLEKKL--------PFWFLSRVDQESITVYPNRPRYCGFM-SVFQYCFGCE----DST
TDAQSTDTTLELEVLKQKYRLKDISTLLEKQHDLIKLIIQK-ME----------------
----------------IVSEAED--------------EDSNDLFQH--------------
------------------------------------------------------------
------KFRKRQ--------LEHRNSK---WD----------------------TVLKAV
KSNV-----------------SNPSTEKSSSLL------------------
>Coelacanth_TRPA1_ENSLACG00000013023
-------MKEQDHCSG---------KMSKGCSLKELKPN-QNSSESFYTSV-------SK
EDE-TKENVGED-IFQLISDGNITAVQNIIMKN----------------SDCLSKLDKLN
ATPLHYAAGDGNLEIMQ----------------MIM---------------DDAEYEVLN
VMDC----------------------------------NGN---TP----------L---
-----HWATEKNQIESVKMLLDRGANPNILNSAVESPLHLAIKLSHNEMVEVLLSYHNTD
VNLG------------------GE--LENTPLILACWI---DNHGAVRILFDHGALLCKP
NRFKIYAIHVAAFAGSKTSMELLLTKGEELGYTREKQINFIDKSLNSPLHLAIHGGNIET
IKCCIDNGANLELQENNKSMALHLACSQGAIETVKLILLSYSGKKDLVNIPDGIMQTPLH
RAAVFDHYEVVDYLLSKGANIDSVDCE----------------LRSALLLATSCGAWKTV
NLLVS---KGVNTKLKDKSGCN-----FLHLVALQPRGLKNLNEEVLQSNCIKELLNDVD
NDGCTPLHYACKQGVSDSVNNMIGLKVCVLSKTKNKRSALHFAAAYGRFHTCRNLLQNMS
DTRLLNEGDEKGMTPLHMAAENGHAK-----------VVQLLLKKGALTLCD--------
--FKEYTSLHYAALGGYTQTMQVLLDTHLKLMDETEEEGNTALHLAAREGHTSAVCLLLA
KGAKITLNKSNASFLHEAVH-HGRKDVTHAIIFSERWHEAIMSFD-FTSDNGCSLLDMIA
YLPEAYRWVLDRSMNESSEDKRSPNFFIEYDFRYLQVPLYMKEMTKENKALHFEPLICMN
NMVRFKRMELLTHPVCREYLRMKWIAYGIKAHVINLAVYLLG------LLPLTALIVYPR
EFTMLTARYPS-ALNVLCVFLAQVPH----------------------FVTVCMFIVLFM
SLFGVCKELVQLFQQRWK--------------YLMDCSNLLD----WSIIVFNILFVVPM
LFGNFNGCHWEFGSIAVFLSWVNLLLYFQRFEQCGIYVVMFWE-----------------
--------------ILKTLFRIVLLFFFLILAFGL---TFYALMNSQV------------
---------------------------AYSS------PVFSTIRVFTMMLGEINYQDSFL
IPLMENKMAYPGLTFIMLIVFVLLMPILLMNLLIGLAVGDIAEVQRNASLKRIAMQIQLH
T-SLENKL--------PLWFLKRVDQLTLKVYPNRSRFCGLGRRKAIYFIGGEWRLLPRK
LPAYSDVSVLELELKKQKYRLKDMSALLHKQHELIKLIIQK-ME----------------
----------------IVSETED--------------QDDQDLSQY--------------
------------------------------------------------------------
------S-KAKS--------MTRFQWG---WS---------------------ISALLTF
NTKICY-----------------------SDVV------------------
>Elephant_shark_XM_007887335.1_TRPA1
-------MLQIL-------------KTGTICNS--------------YSFV-------EK
SQE-CSQNRS-D-IFEVIAAGDVKSVERLMEKD----------------HDCLNRLDEDK
STPLHHAAGGGHLDILK----------------LII---------------DDADFEVLN
VIDS----------------------------------NGN---TA----------L---
-----HWATEKNQVKCVQGLLDRGANPNILNNALLSPLHVAVNLHHSAVLEVLASNKTSD
LNLA------------------GE--LENTPVMLACSI---DNHEGISILLSHGASLCKQ
NKLGHSALHQAAFSGAKKSLELILRKGMDMGYTSEYLLNIPDKTHCSPLHLALHGGNMET
IKICIENGAKLDFQQDDIPAPLHFACMQGQIKVVKLILSKFTAANSILNVLDDVKQTPLH
KAAMYDHSHLVEYLIEQGAEMNIVDCE----------------TRTPLLWAASRGSWKSV
KVLLA---RGANVKIKNDAGCN-----FFHLTLLQPGGLKNLGQEILSCEYIQELLYDQD
IDGCTPLHYACRQGLLDSVDKIMNLKMCLHIKTKDKKTPLHFAAGYGRLKTCQRLLQNLK
DTKFLNEGDGKGMTPLLLAAQNGHTK-----------VVQLLLMKGSLLLWD--------
--YEGWTSLHFAAAGGYSHTMKILLETNIKLIDQVDLKGNTALHFAASEGHVNAVRLLMT
KGAAIKLNENDASFLHEAIH-KGRKEVALAIVESERFYEAMCIFV-HGSPMGCPVLEMIE
HLPESFKGLLDKCMKESSEDKKNINFSIEYNFKYLQCPINYRKIIKGDKLITYKPLTTLN
AMVKYNQTELLNHPVCKTYLQMKWRAYGIMAHVINMLLYSVL------LLPMTVLILVAR
PHG-VNSQ-SHILLNVT----------QTAIGTQTEIEE-------HTVEKICATIVFIM
SGLGICKEIIQLFQQRWQ--------------YLVDSSNLLD----WIIYVMSIVFVTPW
VLDMSIAWQWQCGIIAALSSWVNFLLFLQRFEISGIYVVMFAE-----------------
--------------ILNTMFHIIILFFFLILAYGL---TFYILLYEQI------------
---------------------------AYES------LPLSLMKTLAMMLGDINYQETFF
IPFKEGRLQFPLLTFIILLIFMLIIPILLMNLLIGLAVGDIASVQRNAKLKRMTMQIFLH
T-SLEKKL--------PKWFLKIVDQQSIKIYPN-KPSCFLVGNMFEYMLPKQSFDKDSC
DDETIAPAKLELQLEKQKNLLKDMSEVMQKQHELLQLIIQK-LE----------------
----------------INSETED--------------QEAIEHLHY--------------
------------------------------------------------------------
------SKAKAS--------ISQK------------------------------------
---------------------------------------------------