Ensembl_ID,HGNC_ID,Trait,n_sig_probes,frac_sig_probes,frac_bg_probes,n_trait_probes,n_bg_probes,OR,conf.lower,conf.upper,p,fdr
ENSG00000109320,NFKB1,obesity,255,0.054901960784313725,0.0013071173459994845,156,108636,44.35552847236594,23.312928675248084,78.36285579160378,2.4607634216109128e-18,2.1890541271413747e-14
ENSG00000109320,NFKB1,smoking cessation,255,0.07450980392156863,0.008293751610884054,920,108636,9.62773411775967,5.667154993921641,15.461261526712743,1.1517234044339062e-12,4.7287105162815185e-9
ENSG00000109320,NFKB1,alcohol consumption,255,0.09803921568627451,0.02750469457638352,3013,108636,3.843295965282002,2.431998059958296,5.8294788083669005,6.20900117601541e-8,8.90526698358954e-5
ENSG00000109320,NFKB1,body mass index (BMI),255,0.06666666666666667,0.01563938289333186,1716,108636,4.495723538823368,2.5694686365550634,7.3734955981457855,8.327961864192988e-7,8.890099290026015e-4
ENSG00000109320,NFKB1,lung function,255,0.0196078431372549,9.113001215066828e-4,104,108636,21.9254209477905,6.905914156625066,53.56684476646737,5.153589776903562e-6,0.004105564990182502
ENSG00000144354,CDCA7,maternal pre-pregnancy obesity,697,0.010043041606886656,0.0013719694667734777,156,108603,7.384414011006097,2.907458468141852,15.675194062727334,7.131582826089316e-5,0.03844931649924416
ENSG00000117139,KDM5B,SETD1B-related syndrome,54,0.37037037037037035,0.015396777247699675,1695,108789,37.61233935921824,20.466447471172344,67.53292892961768,1.2255647862868564e-22,2.1804840156020322e-18
ENSG00000166261,ZNF202,Kabuki syndrome (KS),95,0.11578947368421053,0.016442561326434013,1800,108803,7.833330988637884,3.7603229657238075,14.779866341716021,5.358952372869858e-7,5.959043393790181e-4
ENSG00000172262,ZNF131,myalgic encephalomyelitis/chronic fatigue syndrome,74,0.16216216216216217,0.033958136071556615,3706,108781,5.505762321150279,2.6980438340126858,10.328784945934874,7.358739544144336e-6,0.005380448262584985
ENSG00000113916,BCL6,air pollution (NO2),135,0.26666666666666666,0.04621539593488458,5061,108730,7.504821910500036,4.969433069917291,11.104946403261241,7.738282013409415e-18,5.900440035224678e-14
ENSG00000113916,BCL6,multiple sclerosis,135,0.22962962962962963,0.06558447530580337,7162,108730,4.24690404447342,2.745520593572036,6.400798405112202,7.706436578156762e-10,1.8696866016323506e-6
ENSG00000113916,BCL6,Crohn's disease (CD),135,0.11851851851851852,0.017400901315184403,1908,108730,7.592904918403864,4.195083529165165,12.879130540034062,2.428617232895255e-9,4.985670954068624e-6
ENSG00000113916,BCL6,alcohol consumption,135,0.1037037037037037,0.027582084061436585,3013,108730,4.079056495497237,2.162726578402676,7.123050525470454,2.50847879578736e-5,0.015568611130831434
ENSG00000138468,SENP7,Werner syndrome,342,0.04093567251461988,0.00583648632476272,648,108627,7.270738637864871,3.9084781073691195,12.46422254566918,2.655180528143166e-8,4.441667381682328e-5
ENSG00000138468,SENP7,ancestry,342,0.0935672514619883,0.03957579607279958,4331,108627,2.504972852260218,1.6816002745033731,3.616176133351072,9.372928760463225e-6,0.0065826325340753245
ENSG00000146232,NFKBIE,smoking cessation,150,0.08666666666666667,0.008342761481645006,920,108717,11.279348175557514,5.833732411957268,20.0273645402461,6.521541777004772e-10,1.6575585349887127e-6
ENSG00000146232,NFKBIE,obesity,150,0.04,0.0013797290212202323,156,108717,30.151075408799187,10.717122801321613,68.7441996124099,9.475459782182914e-8,1.2041730139857452e-4
ENSG00000146232,NFKBIE,body mass index (BMI),150,0.08666666666666667,0.015664523487587036,1716,108717,5.962471151760086,3.089820588695216,10.569577869519227,8.82691636272231e-7,9.237973742358888e-4
ENSG00000214548,MEG3,Kabuki syndrome (KS),56,0.17857142857142858,0.016453869416944728,1800,108789,12.996691511190846,5.836438304236818,26.152982143226712,2.6629200227416297e-8,4.441667381682328e-5
ENSG00000214548,MEG3,Nicolaides–Baraitser syndrome (NCBRS),56,0.07142857142857142,0.0031528922960961125,347,108789,24.323375397213226,6.3514784204657015,66.6211003856806,3.2712894535898596e-5,0.019618547706220082
ENSG00000214548,MEG3,ancestry,56,0.17857142857142858,0.0397190892461554,4331,108789,5.256137364364283,2.363165806828111,10.567865900948556,6.548652553207485e-5,0.03603446701313912
ENSG00000214548,MEG3,Klinefelter syndrome,56,0.05357142857142857,0.0014707369311235511,163,108789,38.43192580624222,7.600820904646194,120.47212857455223,8.621065640683437e-5,0.046014937857147845
ENSG00000104043,ATP8B4,body mass index (BMI),43,0.23255813953488372,0.015681300095595263,1716,108792,19.0189380220171,8.34731435913152,39.55270440550373,1.1056514746396153e-9,2.502732677900419e-6
ENSG00000104043,ATP8B4,birth weight,43,0.16279069767441862,0.008125597470402236,891,108792,23.72846346465081,8.888049396774315,54.251203855641656,6.004227321645924e-8,8.902100924801423e-5
ENSG00000104043,ATP8B4,hepatic fat,43,0.06976744186046512,1.7464519449959557e-4,22,108792,431.59838100978834,78.1934873351926,1599.526355671887,8.799416520602437e-8,1.1455337970418416e-4
ENSG00000104043,ATP8B4,blood high-density lipoprotein (HDL) levels,43,0.046511627906976744,3.676740936833591e-5,6,108792,1334.234939829509,116.14494418788091,8191.999999985097,2.2847542952313315e-6,0.00210256483634435
ENSG00000104043,ATP8B4,waist to hip ratio (WHR),43,0.046511627906976744,5.515111405250386e-5,8,108792,881.0271179431065,84.49773313827498,4299.727210771426,4.262732949009435e-6,0.003447323805354221
ENSG00000104043,ATP8B4,blood triglyceride levels,43,0.046511627906976744,7.353481873667182e-5,10,108792,674.4642341161477,66.36363954152576,3574.47578882217,6.8473806334007205e-6,0.0052172145999073724
ENSG00000104043,ATP8B4,metabolic trait,43,0.046511627906976744,1.6545334215751158e-4,20,108792,293.8440370094503,32.059645401631485,1318.0352246898592,2.883865670510361e-5,0.017692681627987414
ENSG00000186480,INSIG1,birth weight,13,0.3076923076923077,0.008150550874323467,891,108827,54.00373303068423,12.141252563424228,195.2797820842878,3.007587010738713e-6,0.0026195161197574515
ENSG00000124243,BCAS4,neurodevelopmental presentations and congenital anomalies (ND/CAs),28,0.25,0.0076830467507880635,843,108811,43.03460374868652,15.414147112894243,105.70096804334243,1.6767158028766805e-9,3.579788239141713e-6
ENSG00000198131,ZNF544,Klinefelter syndrome,67,0.07462686567164178,0.001452326019615593,163,108791,55.44096693769228,17.165733879824145,139.27646583897715,6.340049562087166e-8,8.90526698358954e-5
ENSG00000198131,ZNF544,neurodevelopmental presentations and congenital anomalies (ND/CAs),67,0.1044776119402985,0.00768445919239643,843,108791,15.065839624236176,5.791442944710598,33.13942639276308,9.46622742757394e-7,9.399286493139026e-4
ENSG00000198131,ZNF544,primary Sjögren's Syndrome (pSS),67,0.16417910447761194,0.0285317719296633,3115,108791,6.687790319365672,3.156009188083604,12.916848358121612,3.042810293676103e-6,0.0026195161197574515
ENSG00000198429,ZNF69,smoking cessation,7,0.42857142857142855,0.008426295186811976,920,108826,88.21971276615744,12.90399641100128,521.0348583615822,2.054651800697849e-5,0.0129020046896762
ENSG00000140853,NLRC5,soluble tumor necrosis factor receptor 2 (sTNFR2) levels in plasma,81,0.20987654320987653,0.0012778906530113172,156,108773,207.7249617795432,110.94171124848418,367.9341899268311,2.1865754398172344e-32,1.1670846410024488e-27
ENSG00000140853,NLRC5,mixed connective tissue disease (MCTD),81,0.12345679012345678,7.906373824386567e-4,96,108773,177.98287108755292,79.03533215734188,366.40448929432677,3.1291971825518834e-19,3.3404179923741356e-15
ENSG00000140853,NLRC5,abdominal obesity,81,0.04938271604938271,8.274112141799895e-5,13,108773,620.6868427263516,137.82841496543543,2533.8891696662913,2.023189935812771e-10,5.399388141200332e-7
ENSG00000140853,NLRC5,primary Sjögren's Syndrome (pSS),81,0.19753086419753085,0.02849052614159764,3115,108773,8.393692011964639,4.52696748282613,14.694107344934814,1.1253505249575654e-9,2.502732677900419e-6
ENSG00000140853,NLRC5,obesity,81,0.06172839506172839,0.0013882121482353157,156,108773,47.257362593767475,14.730193076189522,117.55005745354806,1.3298232780105387e-7,1.5773181658625e-4
ENSG00000140853,NLRC5,alcohol consumption,81,0.16049382716049382,0.02758037380599965,3013,108773,6.74009056871149,3.4115725312724745,12.331594765651564,3.5430298512131144e-7,4.023600389542553e-4
ENSG00000140853,NLRC5,waist circumference (WC),81,0.08641975308641975,0.006306712143638587,693,108773,14.904668938629136,5.7697153464848485,32.44242789973058,9.509348395868991e-7,9.399286493139026e-4
ENSG00000140853,NLRC5,body mass index (BMI),81,0.09876543209876543,0.015702426153549134,1716,108773,6.8690496018780145,2.8538753364714786,14.295623633244471,4.3584308366258846e-5,0.0247480048835007
ENSG00000177311,ZBTB38,schizophrenia,139,0.02877697841726619,8.092921452679401e-4,92,108737,36.57365747814823,9.611119074880602,98.84734170986955,6.5136540859458455e-6,0.0050386418382226015
ENSG00000185811,IKZF1,residential proximity to major roadways at birth,54,0.07407407407407407,0,4,108780,Inf,1354.3491655457321,Inf,5.4101427856232056e-14,3.6095796397829825e-10
ENSG00000185811,IKZF1,Coffin–Siris syndrome (CSS),54,0.12962962962962962,0.0023349880492737635,261,108780,63.60922088893485,24.02077052358233,143.12789593767917,6.768514999869283e-11,1.9014183585159104e-7
ENSG00000185811,IKZF1,Nicolaides–Baraitser syndrome (NCBRS),54,0.1111111111111111,0.003134767420481706,347,108780,39.74111735464965,13.802797547188991,93.91663495241824,2.2837755073757426e-8,4.063217256872676e-5
ENSG00000185811,IKZF1,Kabuki syndrome (KS),54,0.14814814814814814,0.016473616473616472,1800,108780,10.383608234085191,4.225800338253727,22.256483621474075,2.919405116652948e-6,0.0025970541350225185
ENSG00000185811,IKZF1,neurodevelopmental presentations and congenital anomalies (ND/CAs),54,0.1111111111111111,0.007694429123000552,843,108780,16.119034961445294,5.621588493872902,37.851373245148594,3.9932167632344275e-6,0.0032790453036559628
ENSG00000132128,LRRC41,gender,57,0.3684210526315789,0.00730819437039216,816,108782,79.20522798401677,43.703016545901434,139.9652404617217,3.024154391401947e-30,8.070712032053946e-26
ENSG00000132128,LRRC41,Claes-Jensen syndrome,57,0.21052631578947367,0.009367358570351713,1031,108782,28.180848133449008,13.534758176158718,54.36687298598156,2.3450763707483485e-13,1.251684512886931e-9
ENSG00000132128,LRRC41,Klinefelter syndrome,57,0.08771929824561403,0.001452446176757184,163,108782,66.18735567961957,20.317408077906475,167.32646786037648,2.7845679569776988e-8,4.503827718293475e-5
ENSG00000132128,LRRC41,ancestry,57,0.21052631578947367,0.03970325973047011,4331,108782,6.449564151861396,3.1030952101449167,12.408922467939147,2.066864900561335e-6,0.00193541954504318
ENSG00000132128,LRRC41,neurodevelopmental presentations and congenital anomalies (ND/CAs),57,0.10526315789473684,0.007694287657884577,843,108782,15.172648053813043,5.306128212575126,35.49876106847901,5.499696484556675e-6,0.004316857350929596
ENSG00000132128,LRRC41,epithelial ovarian cancer risk,57,0.05263157894736842,6.251034178448641e-4,71,108782,88.68335175306332,17.33686409172304,282.48923920130903,7.588450604650275e-6,0.005473426365178492
ENSG00000074800,ENO1,ancestry,130,0.16153846153846155,0.03964166145469262,4331,108724,4.667575616138166,2.774727487180304,7.503054166120536,5.027428207938649e-8,7.66682801710644e-5
ENSG00000074800,ENO1,maternal smoking,130,0.13076923076923078,0.027546815790441853,3012,108724,5.310587334133747,2.9847500498956276,8.89770112068038,1.3179828608358858e-7,1.5773181658625e-4
ENSG00000173209,AHSA2,air pollution (NO2),32,0.28125,0.046431689720141535,5061,108805,8.037243891482685,3.270923396011244,18.039420830165398,1.0665408184323603e-5,0.007298284126131697
ENSG00000173209,AHSA2,Kabuki syndrome (KS),32,0.1875,0.01648821285786499,1800,108805,13.76674110214909,4.627421926763214,34.26339982016288,1.2721898274409261e-5,0.008383102720945609
ENSG00000261589,CTC-462L7.1,maternal smoking,59,0.1864406779661017,0.027585255997793916,3012,108790,8.078756463908386,3.778852457270825,15.793076600769021,5.891564127379151e-7,6.417596638752289e-4
ENSG00000163803,PLB1,multiple sclerosis,35,0.5142857142857142,0.06565935075916327,7162,108804,15.064699781343275,7.322781861400574,31.104298772245066,8.003428633382015e-13,3.5598583608897087e-9
ENSG00000163803,PLB1,birth weight,35,0.2,0.008124701297746407,891,108804,30.521757601814993,11.221800522186069,71.70215064861391,1.3259490241517843e-8,2.4404320401414305e-5
ENSG00000102554,KLF5,preterm birth,64,0.125,0.01409318231962933,1541,108776,9.993821170042393,4.106601587631651,21.121938833871464,3.4772704610258303e-6,0.002946020807257995
ENSG00000102554,KLF5,Nicolaides–Baraitser syndrome (NCBRS),64,0.0625,0.0031532691034787085,347,108776,21.06611627896948,5.530658472180261,57.329500725248344,5.5474780823005304e-5,0.03084340027529071
ENSG00000160094,ZNF362,maternal smoking,7,0.5714285714285714,0.027640453568081157,3012,108826,46.8819960446182,7.92814679934303,318.5710439558636,1.9164577364322955e-5,0.012324208636394432
ENSG00000136045,PWP1,chemotherapy for breast cancer,6,0.5,0.005026233816354097,550,108829,198.8034887129551,26.41438502717775,1585.5428704519893,2.538238516317533e-6,0.0022962454374313274
ENSG00000187147,RNF220,smoking cessation,9,0.6666666666666666,0.008398882599426597,920,108824,234.82947270441275,50.264805396534086,1455.7021124004843,2.9511795834122983e-11,9.265835897919495e-8
ENSG00000187147,RNF220,SETD1B-related syndrome,9,0.4444444444444444,0.015538851723884438,1695,108824,50.68829477556575,10.044220815608325,234.73597821449232,6.939995064982172e-6,0.0052172145999073724
ENSG00000167658,EEF2,ancestry,6,0.6666666666666666,0.03975998823832102,4331,108828,48.301357924415086,6.919256058990301,530.6358496890722,3.5216864715889573e-05,0.020656045650666
ENSG00000197566,ZNF624,educational attainment,8,0.25,6.432049986217035e-4,72,108830,523.8536352675968,50.109982222340136,3261.7012860576356,1.2052422641464783e-5,0.008041225731102285
ENSG00000122386,ZNF205,puberty,11,0.36363636363636365,0.003969785521310029,436,108822,143.8049735704154,30.638860028896058,557.9017114519487,8.199418196174197e-8,1.0941098655519944e-4
ENSG00000122386,ZNF205,preterm birth,11,0.45454545454545453,0.014114792964657882,1541,108822,58.0900154183964,14.031825064435326,227.91008595234686,2.433700005489079e-7,2.8238856041952086e-4
ENSG00000067208,EVI5,maternal smoking,9,0.5555555555555556,0.027631772403146366,3012,108824,43.97511055844102,9.459774173203616,220.9511959102871,1.8578616445607729e-6,0.0017707743799719867