Table S4. GO-biological process of DE proteins. Terms were considered significant if they had a p-value less than or equal to 0.05 and more than three proteins. See also Figure 5.,Column 2,Column 3,Column 4,Column 5,Column 6,Column 7
Term,Overlap,P.value,Adjusted.P.value,,,Proteins
respiratory electron transport chain (GO:0022904),29/94,1.40E-17,7.14E-14,7.20e+9,2.79e+9,NDUFB9;NDUFA13;NDUFB7;NDUFB10;UQCRB;COX4I1;NDUFB4;NDUFA10;ETFDH;UQCRFS1;NDUFV3;CYC1;NDUFV2;NDUFV1;NDUFA6;NDUFA4;SDHA;COX6C;SDHB;COX6B1;ALDH5A1;NDUFS7;UQCRQ;GPD2;NDUFS3;UQCRC1;CYCS;NDUFS1;UQCRC2
viral process (GO:0016032),42/220,2.40E-16,6.12E-13,4.46e+9,1.60e+9,RPL4;RPL5;VCP;RPL3;NUP107;RPL32;RPLP1;RAB1B;RPL36A;AP2A1;RPL10A;RPL9;RPS14;RPL7A;RPS16;RPS19;RPL36;AP2S1;AP1S1;RCC1;APOE;RAC1;RPS11;RPL18;RPL17;RPS13;AP2M1;RPL19;RANBP1;RPS8;RPS5;VTA1;RPS6;RPSA;AP2B1;RPL27A;PI4KA;CHMP4B;RPS21;PPIA;EIF3D;RAN
translation (GO:0006412),43/232,3.25E-16,5.53E-13,4.33e+9,1.54e+9,RPL4;RPL5;RPL3;RPL32;RPLP1;RPL36A;EPRS;RPL10A;RPL9;NARS;RPS14;RPL7A;RPS16;RPS19;LARS;RARS;RPL36;EIF4H;EIF4EBP2;IARS2;RPS11;RPL18;RPL17;RPS13;EIF4B;RPL19;EEFSEC;RPS8;RPS5;RPS6;MRPS2;SARS;RPSA;EEF2;TUFM;EEF1A1;EEF1G;AIMP2;PPA1;RPL27A;EEF1A2;RPS21;AARS
SRP-dependent cotranslational protein targeting to membrane (GO:0006614),26/89,2.94E-15,3.75E-12,6.82e+8,2.28e+8,RPL4;RPL5;RPL3;RPL32;RPLP1;ZFAND2B;RPL36A;SRP14;RPL10A;RPL9;RPL7A;RPS14;RPS16;RPS19;RPL36;RPS11;RPL18;RPL17;RPS13;RPL19;RPS8;RPS5;RPS6;RPSA;RPL27A;RPS21
protein targeting to ER (GO:0045047),27/97,3.27E-15,3.34E-12,6.50e+9,2.17e+9,RPL4;RPL5;RPL3;RPL32;RPLP1;RPL36A;SRP14;RPL10A;RPL9;RPS14;RPL7A;RPS16;RPS19;RPL36;RPS11;RPL18;RPL17;RPS13;RPL19;PMM1;RPS8;RPS5;RPS6;RPSA;RPL27A;CHMP4B;RPS21
mitochondrial ATP synthesis coupled electron transport (GO:0042775),25/85,8.43E-15,7.17E-12,6.86e+8,2.22e+9,NDUFB9;NDUFA13;NDUFB7;NDUFB10;UQCRB;COX4I1;NDUFB4;NDUFA10;UQCRFS1;NDUFV3;CYC1;NDUFV2;NDUFV1;NDUFA6;NDUFA4;SDHA;COX6C;COX6B1;NDUFS7;UQCRQ;NDUFS3;UQCRC1;CYCS;NDUFS1;UQCRC2
cotranslational protein targeting to membrane (GO:0006613),25/93,8.38E-14,6.11E-11,6.27e+9,1.89e+9,RPL4;RPL5;RPL3;RPL32;RPLP1;RPL36A;SRP14;RPL10A;RPL9;RPL7A;RPS14;RPS16;RPS19;RPL36;RPS11;RPL18;RPL17;RPS13;RPL19;RPS8;RPS5;RPS6;RPSA;RPL27A;RPS21
"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)",27/112,1.55E-13,9.88E-11,5.63e+9,1.66e+9,RPL4;RPL5;RPL3;RPL32;RPLP1;RPL36A;SMG9;RPL10A;RPL9;RPS14;RPL7A;RPS16;RPS19;PPP2R1A;RPL36;RPS11;RPL18;RPL17;RPS13;RPL19;RPS8;RPS5;RPS6;RPSA;RPL27A;RNPS1;RPS21
viral transcription (GO:0019083),26/113,1.40E-12,7.94E-10,5.37e+9,1.47e+9,RPL4;RPL5;RPL3;NUP107;RPL32;DHX9;RPLP1;RPL36A;RPL10A;RPL9;RPS14;RPL7A;RPS16;RPS19;RPL36;RPS11;RPL18;RPL17;RPS13;RPL19;RPS8;RPS5;RPS6;RPSA;RPL27A;RPS21
viral gene expression (GO:0019080),25/110,5.06E-12,2.58E-09,5.30e+9,1.38e+9,RPL4;RPL5;RPL3;NUP107;RPL32;RPLP1;RPL36A;RPL10A;RPL9;RPS14;RPL7A;RPS16;RPS19;RPL36;RPS11;RPL18;RPL17;RPS13;RPL19;RPS8;RPS5;RPS6;RPSA;RPL27A;RPS21
"RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)",37/236,7.69E-12,3.57E-09,3.66e+9,9.36e+9,DHX9;CSTF2;SRRT;PRCC;HNRNPR;YBX1;PRPF19;PRPF8;ELAVL1;CCAR1;SART3;SNRPD2;PABPN1;POLR2A;SNRPD1;PCBP1;SYMPK;RALY;SNRPD3;SRRM2;HSPA8;CPSF7;CPSF1;FUS;LSM5;SNW1;PHF5A;DDX39B;HNRNPUL1;HNRNPA2B1;SRSF3;RNPS1;HNRNPH2;SRSF4;SRSF5;SRSF6;SNRNP200
neutrophil degranulation (GO:0043312),56/479,9.32E-12,3.96E-09,2.73e+9,6.93e+9,GPI;PYGB;HSP90AB1;GDI2;HMGB1;SRP14;PSMD7;FTH1;RAC1;CTSD;KCMF1;ACTR2;HSP90AA1;AHSG;RHOG;MIF;RHOA;CKAP4;APRT;EEF1A1;ACLY;PKM;CSNK2B;ALDOC;CD47;ATP6V0C;PPIA;PAFAH1B2;KPNB1;CSTB;RAB5B;VCP;PSMD12;RAP1B;PSMB7;COMMD9;CAND1;PSMB1;MLEC;LTA4H;CCT8;ATP6V0A1;DYNC1H1;HSPA8;PTPRN2;TMEM30A;IDH1;EEF2;PRDX6;CPPED1;RAB10;PFKL;TOLLIP;RAB18;LAMTOR2;ACTR10
"mRNA splicing, via spliceosome (GO:0000398)",39/261,9.60E-12,3.77E-09,3.49e+9,8.85e+9,DHX9;CSTF2;SRRT;PRCC;HNRNPR;YBX1;PRPF19;PRPF8;ELAVL1;CCAR1;SART3;SNRPD2;PABPN1;POLR2A;SNRPD1;PCBP1;SYMPK;RALY;SNRPD3;DCPS;SRRM2;HSPA8;CPSF7;CPSF1;FUS;LSM5;SNW1;PHF5A;DDX39B;HNRNPUL1;HNRNPA2B1;STRAP;SRSF3;RNPS1;HNRNPH2;SRSF4;SRSF5;SRSF6;SNRNP200
neutrophil activation involved in immune response (GO:0002283),56/483,1.30E-11,4.73E-09,2.71e+8,6.78e+8,GPI;PYGB;HSP90AB1;GDI2;HMGB1;SRP14;PSMD7;FTH1;RAC1;CTSD;KCMF1;ACTR2;HSP90AA1;AHSG;RHOG;MIF;RHOA;CKAP4;APRT;EEF1A1;ACLY;PKM;CSNK2B;ALDOC;CD47;ATP6V0C;PPIA;PAFAH1B2;KPNB1;CSTB;RAB5B;VCP;PSMD12;RAP1B;PSMB7;COMMD9;CAND1;PSMB1;MLEC;LTA4H;CCT8;ATP6V0A1;DYNC1H1;HSPA8;PTPRN2;TMEM30A;IDH1;EEF2;PRDX6;CPPED1;RAB10;PFKL;TOLLIP;RAB18;LAMTOR2;ACTR10
neutrophil mediated immunity (GO:0002446),56/487,1.80E-11,6.12E-09,2.68e+9,6.64e+9,GPI;PYGB;HSP90AB1;GDI2;HMGB1;SRP14;PSMD7;FTH1;RAC1;CTSD;KCMF1;ACTR2;HSP90AA1;AHSG;RHOG;MIF;RHOA;CKAP4;APRT;EEF1A1;ACLY;PKM;CSNK2B;ALDOC;CD47;ATP6V0C;PPIA;PAFAH1B2;KPNB1;CSTB;RAB5B;VCP;PSMD12;RAP1B;PSMB7;COMMD9;CAND1;PSMB1;MLEC;LTA4H;CCT8;ATP6V0A1;DYNC1H1;HSPA8;PTPRN2;TMEM30A;IDH1;EEF2;PRDX6;CPPED1;RAB10;PFKL;TOLLIP;RAB18;LAMTOR2;ACTR10
mRNA processing (GO:0006397),40/283,3.06E-11,9.75E-09,3.30e+9,7.99e+9,DHX9;POLDIP3;CSTF2;SRRT;PRCC;HNRNPR;YBX1;PRPF19;PRPF8;ELAVL1;CCAR1;SART3;SNRPD2;PABPN1;POLR2A;SNRPD1;PCBP1;SYMPK;RALY;SNRPD3;SRRM2;HSPA8;CPSF7;CHTOP;CPSF1;FUS;LSM5;SNW1;PHF5A;SON;DDX39B;HNRNPUL1;HNRNPA2B1;SRSF3;RNPS1;HNRNPH2;SRSF4;SRSF5;SRSF6;SNRNP200
negative regulation of supramolecular fiber organization (GO:1902904),17/54,5.01E-11,1.51E-08,7.35e+9,1.74e+9,HSPA8;TWF2;TBCD;TWF1;CORO1A;TUBB4A;CAMSAP1;CAMSAP2;CAMSAP3;APC;STMN1;SHANK3;SHANK1;PFN2;KANK3;SNCA;CLASP2
nuclear-transcribed mRNA catabolic process (GO:0000956),30/174,6.72E-11,1.90E-08,4.02e+9,9.43e+8,RPL4;RPL5;RPL3;RPL32;RPLP1;RPL36A;SMG9;RPL10A;RPL9;RPS14;RPL7A;RPS16;RPS19;PPP2R1A;RPL36;RPS11;RPL18;RPL17;DCPS;RPS13;EIF4B;RPL19;RPS8;RPS5;RPS6;RPSA;LSM5;RPL27A;RNPS1;RPS21
peptide biosynthetic process (GO:0043043),30/174,6.72E-11,1.80E-08,4.02e+9,9.43e+8,RPL4;RPL5;RPL3;RPL32;RPLP1;RPL36A;RPL10A;RPL9;RPS14;RPL7A;RPS16;RPS19;RPL36;EIF4EBP2;DMD;RPS11;RPL18;RPL17;RPS13;RPL19;RPS8;RPS5;RPS6;SARS;MRPS2;RPSA;EEF1A1;RPL27A;EEF1A2;RPS21
gene expression (GO:0010467),48/411,3.04E-10,7.77E-08,2.73e+8,5.97e+9,RPL4;RPL5;RPL3;NUP107;RPL32;DHX9;POLDIP3;RPLP1;RPL36A;AKR1B1;RPL10A;RPL9;RPL7A;RPS14;RPS16;POLR2A;RPS19;PABPN1;RPL36;EIF4EBP2;SYMPK;RPL18;RPS11;RPL17;RPS13;RPL19;CHTOP;CPSF1;RPS8;RPS5;RPS6;SARS;MRPS2;RPSA;EEF1A1;PPP5C;DDX39B;HNRNPUL1;RPL27A;HNRNPA2B1;EEF1A2;SRSF3;SRSF4;RNPS1;SRSF5;SRSF6;RPS21;PTMA
neuron projection development (GO:0031175),27/167,2.61E-09,6.35E-07,3.77e+9,7.46e+9,NCKAP1;CTNND2;HMGB1;FRY;PPP1R9A;CAMSAP1;CAMSAP2;PPP1R9B;CDC42;MAP2;STMN1;APOE;MAP4;RAC1;NCDN;NEFH;SH3GL2;MINK1;RHOG;DCLK1;CTTN;RAB35;PLP1;PLXNB1;SHANK3;SHANK2;SHANK1
non-canonical Wnt signaling pathway (GO:0035567),23/127,4.20E-09,9.75E-07,4.23e+9,8.15e+9,PSMD12;CLTC;CAMK2A;AP2A1;AP2B1;RHOA;GNAO1;CDC42;PSMB7;PPP3CB;PSMD7;GNG2;PSMC6;AGO3;PSMD5;GNB1;PSMB1;AP2S1;CTNNB1;RAC1;CALM1;PLCB1;AP2M1
"mitochondrial electron transport, NADH to ubiquinone (GO:0006120)",14/46,4.23E-09,9.38E-07,7.10e+9,1.37e+9,NDUFB9;NDUFA13;NDUFB7;NDUFA6;NDUFB10;NDUFA4;NDUFB4;NDUFA10;NDUFS7;NDUFS3;NDUFS1;NDUFV3;NDUFV2;NDUFV1
cytoplasmic translation (GO:0002181),15/54,4.83E-09,1.03E-06,6.48e+9,1.24e+9,RPL4;RPL32;RPLP1;RPL36A;RPL10A;RPL9;EIF3M;RPL27A;RPL36;EIF4H;RPL18;RPL17;RPS21;EIF4B;RPL19
cellular protein metabolic process (GO:0044267),50/484,8.64E-09,1.76E-06,2.41e+9,4.48e+9,RPL4;RPL5;RPL3;RPL32;PRKCSH;RPLP1;RPL10A;RPL9;PCMT1;RPL7A;RPS14;RPS16;CDH2;RPS19;RPL36;SEPHS1;RPS11;RPS13;ATG3;AHSG;RPS8;RPS5;FBXO2;RPS6;SARS;MRPS2;RPSA;RABGGTB;CKAP4;EEF1A1;AFG3L2;VGF;EEF1A2;L2HGDH;STOML2;RPL36A;TXN;HSP90B1;EIF4EBP2;LTA4H;APOE;RPL18;RPL17;RPL19;SNCA;USP9X;RPL27A;ALB;CPE;RPS21
ribonucleoprotein complex assembly (GO:0022618),25/156,1.22E-08,2.38E-06,3.74e+9,6.82e+9,RPL5;RPL3;HSP90AB1;DHX9;PRPF19;RPS14;ATXN2;SART3;SNRPD2;RPS19;SNRPD1;EIF4H;SNRPD3;EIF4B;DYNC1H1;HSP90AA1;RPS5;CIRBP;RPSA;SNW1;DDX39B;STRAP;SRSF5;SRSF6;SNRNP200
inner mitochondrial membrane organization (GO:0007007),12/36,1.72E-08,3.25E-06,7.78e+8,1.39e+9,LETM1;ATP5B;AFG3L2;NDUFA13;SAMM50;TIMM29;OPA1;TIMM9;ATP5A1;ATP5O;ATP5F1;ATP5J2
dicarboxylic acid metabolic process (GO:0043648),15/59,1.82E-08,3.32E-06,5.93e+9,1.06e+9,ALDH1L1;FH;GOT1;MDH1;MDH2;IDH1;GOT2;IDH2;DLST;SDHA;ACLY;ALDH5A1;MTHFD1;SUCLG1;L2HGDH
cellular macromolecule biosynthetic process (GO:0034645),41/367,2.19E-08,3.85E-06,2.61e+9,4.60e+9,RPL4;RPL5;RPL3;RPL32;RPLP1;RPL36A;AKR1B1;RPL10A;RPL9;PTMS;RPS14;RPL7A;RPS16;RPS19;POLR2A;RPL36;EIF4EBP2;RPS11;RPL18;RPL17;RPS13;RPL19;EEFSEC;RBM14;RPS8;RPS5;RPS6;MRPS2;SARS;RPSA;NAP1L1;EEF2;TUFM;EEF1A1;EEF1G;PPP5C;RPL27A;EEF1A2;RNPS1;RPS21;PTMA
neuron projection morphogenesis (GO:0048812),25/163,3.00E-08,5.11E-06,3.58e+9,6.20e+9,NCKAP1;BRSK1;SPTBN4;CTNND2;CDC42;MAP2;MAP6;RAC1;NEFH;LINGO1;FARP1;MINK1;RHOG;BAIAP2;DCLK1;RAB10;AFG3L2;CTTN;MAP1A;MAP6D1;CTNNB1;PLXNB1;SHANK3;SHANK2;SHANK1
canonical glycolysis (GO:0061621),10/25,3.60E-08,5.93E-06,9.33e+9,1.60e+9,GPI;PFKL;TPI1;PKM;PGK1;ALDOC;ENO1;ENO2;PFKM;HK1
glycolytic process through glucose-6-phosphate (GO:0061620),10/25,3.60E-08,5.74E-06,9.33e+9,1.60e+9,GPI;PFKL;TPI1;PKM;PGK1;ALDOC;ENO1;ENO2;PFKM;HK1
glucose catabolic process to pyruvate (GO:0061718),10/25,3.60E-08,5.57E-06,9.33e+9,1.60e+9,GPI;PFKL;TPI1;PKM;PGK1;ALDOC;ENO1;ENO2;PFKM;HK1
pyruvate metabolic process (GO:0006090),13/46,4.10E-08,6.16E-06,6.60e+9,1.12e+9,SLC16A1;TPI1;PDHA1;PDHB;ENO2;HK1;LDHB;PFKL;PKM;PGK1;DLAT;PFKM;PCK2
mitochondrial transport (GO:0006839),22/135,6.65E-08,9.70E-06,3.80e+9,6.28e+9,SLC25A3;HSP90AA1;STOML2;HSPA4;TIMM9;ATP5A1;AIP;TOMM34;ATP5O;ATP5F1;MFF;GDAP1;ATP5J2;TIMM50;TIMM10B;ATP5B;SLC25A18;SAMM50;CYC1;SLC25A5;SLC25A4;SLC25A22
cellular respiration (GO:0045333),14/57,8.74E-08,1.24E-05,5.73e+9,9.32e+9,UQCRB;MDH2;ETFDH;MTFR1L;SDHA;SDHB;ALDH5A1;NDUFS7;NDUFS3;UQCRC1;CYCS;NDUFS1;UQCRC2;NDUFV2
positive regulation of cytoskeleton organization (GO:0051495),16/77,1.32E-07,1.82E-05,4.85e+9,7.68e+9,NRP1;NCKAP1;DYNC1H1;WDR1;NUMA1;PRKCE;RHOG;PDXP;BAIAP2;CDC42;HAX1;CTTN;CFL2;PTK2B;RAC1;PFN2
regulation of microtubule polymerization (GO:0031113),11/35,1.36E-07,1.83E-05,7.33e+9,1.16e+9,CAMSAP3;CLIP1;NUMA1;MAP2;STMN1;TBCD;RAC1;TUBB4A;CAMSAP1;CAMSAP2;SNCA
antigen processing and presentation of exogenous peptide antigen (GO:0002478),18/97,1.37E-07,1.80E-05,4.33e+9,6.84e+9,DCTN6;DYNC1I2;DYNC1H1;SEC23A;DCTN2;CLTC;AP2A1;AP2B1;ACTR1A;KIF3B;CAPZA2;AP2S1;AP1S1;CTSD;ACTR10;SH3GL2;AP2M1;DYNC1I1
antigen processing and presentation of exogenous peptide antigen via MHC class II (GO:0019886),18/97,1.37E-07,1.75E-05,4.33e+9,6.84e+9,DCTN6;DYNC1I2;DYNC1H1;SEC23A;DCTN2;CLTC;AP2A1;AP2B1;ACTR1A;KIF3B;CAPZA2;AP2S1;AP1S1;CTSD;ACTR10;SH3GL2;AP2M1;DYNC1I1
ncRNA processing (GO:0034470),29/227,1.51E-07,1.88E-05,2.98e+9,4.68e+9,RPL4;RPL5;RPL3;RPL32;RPLP1;SRRT;RPL36A;RPL10A;RPL9;RPS14;RPL7A;RPS16;RPS19;RPL36;RPS11;RPL18;RPL17;RPS13;RPL19;RPS8;RPS5;RPS6;SARS;RPSA;AGO3;RPL27A;HNRNPA2B1;RPS21;AARS
substantia nigra development (GO:0021762),12/43,1.60E-07,1.94E-05,6.51e+9,1.02e+9,YWHAE;CDC42;CNP;YWHAQ;HSPA5;NDUFS3;PLP1;NDRG2;ATP5F1;CALM1;RHOA;COX6B1
antigen processing and presentation of peptide antigen via MHC class II (GO:0002495),18/98,1.61E-07,1.92E-05,4.29e+8,6.70e+9,DCTN6;DYNC1I2;DYNC1H1;SEC23A;DCTN2;CLTC;AP2A1;AP2B1;ACTR1A;KIF3B;CAPZA2;AP2S1;AP1S1;CTSD;ACTR10;SH3GL2;AP2M1;DYNC1I1
cellular response to insulin stimulus (GO:0032869),19/110,2.03E-07,2.35E-05,4.03e+9,6.21e+9,ATP6V1A;ATP6V1G1;GSK3A;ATP6V1G2;GOT1;DENND4C;MYO5A;BAIAP2;RAB10;PKM;APC;ATP6V1B2;ATP6V0D1;ATP6V0C;ATP6V1C1;VAMP2;ATP6V1F;ATP6V0A1;PCK2
hexose biosynthetic process (GO:0019319),12/44,2.11E-07,2.39E-05,6.36e+9,9.78e+9,GPI;TPI1;GOT1;MDH1;MDH2;GOT2;PGK1;AKR1B1;ALDOC;ENO1;ENO2;PCK2
cellular amino acid catabolic process (GO:0009063),9/23,2.22E-07,2.46E-05,9.13e+9,1.40e+9,MCCC2;ALDH5A1;HIBADH;AUH;DBT;ABAT;ADO;BCAT1;HSD17B10
protein targeting to mitochondrion (GO:0006626),13/54,3.25E-07,3.53E-05,5.62e+9,8.39e+9,NDUFA13;HSP90AA1;TIMM29;HSPA4;TIMM9;AIP;TOMM34;MFF;GDAP1;TIMM50;TIMM10B;SAMM50;UQCRC2
regulation of macroautophagy (GO:0016241),19/116,4.77E-07,5.08E-05,3.82e+8,5.56e+8,ATP6V1A;GPSM1;ATP6V1G1;ATP6V1G2;EXOC8;RAB1B;VPS26A;VPS26B;MTOR;UCHL1;LARP1;ATP6V1B2;LAMTOR2;ATP6V0D1;ATP6V0C;ATP6V1C1;SNX5;PAFAH1B2;ATP6V0A1
ATP metabolic process (GO:0046034),13/56,5.12E-07,5.34E-05,5.42e+9,7.85e+9,HSPA8;UQCRB;ATP5A1;ATP1A2;NUDT5;ATP1B1;ATP5F1;ATP5O;ATP5J2;ATP5B;UQCRC1;NDUFS1;UQCRC2
dendrite morphogenesis (GO:0048813),10/32,5.41E-07,5.52E-05,7.29e+9,1.05e+9,CDC42;FARP1;MAP2;CTNND2;MINK1;MAP6;MAP6D1;SHANK3;SHANK2;SHANK1
phagosome maturation (GO:0090382),10/32,5.41E-07,5.41E-05,7.29e+9,1.05e+9,ATP6V1A;ATP6V1G1;ATP6V1G2;ATP6V1B2;ATP6V0D1;CORO1A;ATP6V0C;ATP6V1C1;ATP6V1F;ATP6V0A1
rRNA processing (GO:0006364),26/202,5.69E-07,5.59E-05,3.00e+9,4.32e+8,RPL4;RPL5;RPL3;RPL32;RPLP1;RPL36A;THUMPD1;RPL10A;RPL9;RPS14;RPL7A;RPS16;RPS19;RPL36;RPS11;RPL18;RPL17;RPS13;RPL19;WDR37;RPS8;RPS5;RPS6;RPSA;RPL27A;RPS21
"mitochondrial electron transport, ubiquinol to cytochrome c (GO:0006122)",7/14,6.82E-07,6.57E-05,1.17e+9,1.66e+9,UQCRB;UQCRQ;UQCRC1;UQCRFS1;CYCS;UQCRC2;CYC1
positive regulation of neuron projection development (GO:0010976),17/97,7.11E-07,6.72E-05,4.09e+8,5.79e+9,CAMK2B;NTRK2;NDRG4;UNC13A;SYT1;KIDINS220;CPNE6;TWF2;TWF1;RHOA;RIMS2;RIMS1;NPTN;PTK2B;PLXNB1;APOE;PLXNA4
gluconeogenesis (GO:0006094),11/41,8.14E-07,7.55E-05,6.26e+9,8.78e+9,GPI;TPI1;GOT1;MDH1;MDH2;GOT2;PGK1;ALDOC;ENO1;ENO2;PCK2
termination of RNA polymerase II transcription (GO:0006369),14/68,9.03E-07,8.23E-05,4.80e+9,6.69e+9,CPSF7;CHTOP;CPSF1;POLDIP3;CSTF2;DDX39B;PABPN1;SRSF3;SYMPK;SRSF4;RNPS1;SNRPD3;SRSF5;SRSF6
phagosome acidification (GO:0090383),9/27,1.09E-06,9.76E-05,7.78e+8,1.07e+9,ATP6V1A;ATP6V1G1;ATP6V1G2;ATP6V1B2;ATP6V0D1;ATP6V0C;ATP6V1C1;ATP6V1F;ATP6V0A1
negative regulation of microtubule polymerization or depolymerization (GO:0031111),9/27,1.09E-06,9.59E-05,7.78e+8,1.07e+9,CAMSAP3;APC;STMN1;TBCD;TUBB4A;CAMSAP1;CAMSAP2;SNCA;CLASP2
transmembrane receptor protein tyrosine kinase signaling pathway (GO:0007169),39/396,1.27E-06,0.0001096,2.30e+9,3.12e+9,CYFIP2;ATP6V1A;NCKAP1;NRP1;GSK3A;ARPC1A;AP2A1;FGF1;GIGYF2;ACTG1;CDC42;SIPA1L1;POLR2A;STMN1;AP2S1;PTK2B;RAC1;AP2M1;ATP6V1C1;ATP6V0A1;ATP6V1F;MAPK3;ACTR3;ACTR2;NTRK2;HSP90AA1;ATP6V1G1;ATP6V1G2;ARPC4;PTPN11;AP2B1;BAIAP2;GRIN2B;RHOA;APC;ATP6V1B2;PLCB1;ATP6V0D1;ATP6V0C
long-term synaptic potentiation (GO:0060291),8/21,1.36E-06,0.00011575,8.89e+9,1.20e+9,MPP2;NPTN;PTK2B;GRIN2B;SHANK3;VAMP2;SHANK2;SHANK1
RNA 3'-end processing (GO:0031123),13/61,1.46E-06,0.000122135,4.97e+9,6.68e+9,CPSF7;CHTOP;CPSF1;POLDIP3;CSTF2;DDX39B;PABPN1;SRSF3;SYMPK;SRSF4;RNPS1;SRSF5;SRSF6
hydrogen ion transmembrane transport (GO:1902600),9/28,1.55E-06,0.000127236,7.50e+9,1.00e+9,ATP5B;ATP6V1B2;ATP5O;ATP6V0D1;ATP6V0C;ATP6V1C1;SLC9A1;ATP6V1F;ATP5J2
rRNA metabolic process (GO:0016072),25/200,1.61E-06,0.000130762,2.92e+9,3.89e+9,TRIR;RPL4;RPL5;RPL3;RPL32;RPLP1;RPL36A;RPL10A;RPL9;RPS14;RPL7A;RPS16;RPS19;RPL36;RPS11;RPL18;RPL17;RPS13;RPL19;RPS8;RPS5;RPS6;RPSA;RPL27A;RPS21
ephrin receptor signaling pathway (GO:0048013),15/82,1.82E-06,0.000144805,4.27e+9,5.64e+8,ACTR3;ACTR2;ARPC1A;AP2A1;PTPN11;ARPC4;AP2B1;GRIN2B;RHOA;ACTG1;CDC42;SIPA1L1;AP2S1;RAC1;AP2M1
ferric iron transport (GO:0015682),10/36,1.82E-06,0.000143152,6.48e+9,8.57e+9,ATP6V1A;ATP6V1G1;ATP6V1G2;CLTC;ATP6V1B2;ATP6V0D1;ATP6V0C;ATP6V1C1;ATP6V1F;ATP6V0A1
transferrin transport (GO:0033572),10/36,1.82E-06,0.000140983,6.48e+9,8.57e+9,ATP6V1A;ATP6V1G1;ATP6V1G2;CLTC;ATP6V1B2;ATP6V0D1;ATP6V0C;ATP6V1C1;ATP6V1F;ATP6V0A1
negative regulation of protein polymerization (GO:0032272),8/22,2.06E-06,0.000156779,8.49e+9,1.11e+9,STMN1;TWF2;TBCD;TWF1;TUBB4A;KANK3;PFN2;SNCA
actin filament bundle assembly (GO:0051017),10/37,2.40E-06,0.000180354,6.31e+9,8.16e+9,DMTN;FSCN1;PDXP;BAIAP2;EZR;RHOA;ADD2;HSP90B1;PLS1;RHOB
positive regulation of supramolecular fiber organization (GO:1902905),15/84,2.49E-06,0.000184269,4.17e+9,5.38e+9,NCKAP1;GPX1;WDR1;NUMA1;PRKCE;RHOG;PDXP;BAIAP2;CLIP1;CTTN;CFL2;PTK2B;RAC1;APOE;PFN2
NADH dehydrogenase complex assembly (GO:0010257),13/64,2.59E-06,0.000189073,4.74e+9,6.10e+9,NDUFB9;NDUFA13;NDUFB7;NDUFA6;NDUFB10;NDUFB4;NDUFA10;NDUFS7;NDUFS3;NDUFS1;NDUFV3;NDUFV2;NDUFV1
mitochondrial respiratory chain complex I biogenesis (GO:0097031),13/64,2.59E-06,0.00018641,4.74e+9,6.10e+9,NDUFB9;NDUFA13;NDUFB7;NDUFA6;NDUFB10;NDUFB4;NDUFA10;NDUFS7;NDUFS3;NDUFS1;NDUFV3;NDUFV2;NDUFV1
mitochondrial respiratory chain complex I assembly (GO:0032981),13/64,2.59E-06,0.000183821,4.74e+9,6.10e+9,NDUFB9;NDUFA13;NDUFB7;NDUFA6;NDUFB10;NDUFB4;NDUFA10;NDUFS7;NDUFS3;NDUFS1;NDUFV3;NDUFV2;NDUFV1
mRNA 3'-end processing (GO:0031124),14/74,2.63E-06,0.000183932,4.42e+9,5.67e+9,CPSF7;CHTOP;AHCYL1;CPSF1;POLDIP3;CSTF2;DDX39B;PABPN1;SRSF3;SYMPK;SRSF4;RNPS1;SRSF5;SRSF6
mitochondrion organization (GO:0007005),22/167,2.82E-06,0.000194344,3.07e+8,3.93e+9,STOML2;TIMM9;IDH2;AIP;TOMM34;MTFR1L;MFF;SOD2;HSD17B10;GDAP1;TIMM50;PRDX3;TIMM10B;AFG3L2;ATP5B;SAMM50;OPA1;LONP1;CYCS;NDUFS1;SLC25A4;ATPAF1
cellular response to interleukin-12 (GO:0071349),11/46,2.82E-06,0.000192206,5.58e+9,7.13e+9,CDC42;RAP1B;PITPNA;TCP1;HNRNPA2B1;AIP;TALDO1;MIF;SOD2;PLCB1;PPIA
interleukin-12-mediated signaling pathway (GO:0035722),11/46,2.82E-06,0.000189677,5.58e+9,7.13e+9,CDC42;RAP1B;PITPNA;TCP1;HNRNPA2B1;AIP;TALDO1;MIF;SOD2;PLCB1;PPIA
vesicle-mediated transport (GO:0016192),39/410,2.97E-06,0.000196632,2.22e+9,2.83e+9,SNAP47;SPTBN4;NAPB;RAB5B;STX16;WIPF3;CLTC;CPNE6;AGAP2;VPS26A;AP2A1;VPS26B;FMN2;CDC42;ACTR1A;VPS53;MYO6;RAC1;ATP9A;SNX5;VTI1B;TBC1D10B;NSF;HSPA8;SYT1;STX8;VTA1;RHOG;MYO5A;SCRIB;SYP;HSPA2;ARFGAP2;RHOB;RAB10;RAB35;UBE2O;VAMP2;VAMP3
macromolecular complex assembly (GO:0065003),18/120,3.52E-06,0.000230135,3.50e+9,4.40e+9,DMTN;ST13;HMGA1;EPRS;CD2AP;ADD2;RIMS1;AFG3L2;APC;PPP2R1A;CSNK2B;CAPZA2;PTK2B;DMD;KPNA3;VAMP2;VAMP3;SHANK1
proton transport (GO:0015992),9/31,4.02E-06,0.000259577,6.78e+9,8.42e+8,ATP5B;ATP6V1B2;ATP5O;ATP6V0D1;ATP6V0C;ATP6V1C1;SLC9A1;ATP6V1F;ATP5J2
positive regulation of synaptic transmission (GO:0050806),13/67,4.45E-06,0.000283735,4.53e+8,5.58e+9,MPP2;SYT1;FMR1;CLSTN1;GRIN2B;RIMS2;RIMS1;NPTN;PTK2B;SHANK3;SHANK2;VAMP2;SHANK1
establishment of protein localization to mitochondrial membrane (GO:0090151),6/12,4.50E-06,0.00028362,1.17e+9,1.44e+9,HSP90AA1;NDUFA13;TIMM29;SAMM50;HSPA4;TIMM9
regulation of actin filament polymerization (GO:0030833),13/68,5.29E-06,0.000328965,4.46e+9,5.42e+8,NCKAP1;MTPN;PRKCE;RHOG;TWF2;TWF1;BAIAP2;HAX1;CTTN;PTK2B;RAC1;PFN2;KANK3
regulation of microtubule polymerization or depolymerization (GO:0031110),7/18,5.44E-06,0.00033446,9.08e+9,1.10e+9,CAMSAP3;MAP2;MAP1A;STMN1;CAMSAP1;CAMSAP2;CLASP2
RNA transport (GO:0050658),14/80,6.86E-06,0.000416521,4.08e+9,4.86e+9,RANBP1;CHTOP;RANBP3;POLDIP3;FMR1;ATXN2;DDX39B;TST;HNRNPA2B1;SRSF3;SRSF4;RNPS1;SRSF5;SRSF6
regulation of autophagy (GO:0010506),24/203,6.89E-06,0.000413396,2.76e+9,3.28e+9,ATP6V1A;ATP6V1G1;GSK3A;ATP6V1G2;EXOC8;USP10;VPS26A;VPS26B;HMGB1;MTOR;EEF1A1;UCHL1;HAX1;LARS;EEF1A2;ATP6V1B2;PIP4K2A;VDAC1;LAMTOR2;ATP6V0D1;ATP6V0C;ATP6V1C1;SNX5;ATP6V0A1
positive regulation of cellular protein metabolic process (GO:0032270),15/91,6.98E-06,0.000414062,3.85e+9,4.57e+9,CYFIP2;RPL5;HSP90AA1;POLDIP3;FMR1;CIRBP;LARP4;EEF2;ELAVL1;CLN6;MTOR;ASPH;VIM;EZR;EIF3D
intracellular pH reduction (GO:0051452),9/33,7.12E-06,0.000417436,6.36e+9,7.54e+9,ATP6V1A;ATP6V1G1;ATP6V1G2;ATP6V1B2;ATP6V0D1;ATP6V0C;ATP6V1C1;ATP6V1F;ATP6V0A1
regulation of protein localization to Cajal body (GO:1904869),5/8,7.18E-06,0.000416236,1.46e+9,1.73e+9,CCT3;TCP1;CCT8;CCT7;CCT5
positive regulation of protein localization to Cajal body (GO:1904871),5/8,7.18E-06,0.000411559,1.46e+9,1.73e+9,CCT3;TCP1;CCT8;CCT7;CCT5
regulation of supramolecular fiber organization (GO:1902903),8/26,8.63E-06,0.000489436,7.18e+8,8.37e+9,CAMSAP3;HSPA8;GPX1;MAP2;MAP1A;APOE;CAMSAP1;CAMSAP2
ATP synthesis coupled proton transport (GO:0015986),8/27,1.18E-05,0.000662129,6.91e+9,7.85e+9,ATP5B;STOML2;ATP5A1;CYC1;ATP5O;ATP5F1;ATP6V0A1;ATP5J2
cristae formation (GO:0042407),8/27,1.18E-05,0.000654932,6.91e+9,7.85e+9,LETM1;ATP5B;AFG3L2;SAMM50;ATP5A1;ATP5O;ATP5F1;ATP5J2
regulation of cytoskeleton organization (GO:0051493),15/95,1.20E-05,0.000657214,3.68e+9,4.18e+9,CLIC4;PHLDB1;DMTN;TWF2;BAIAP2;CORO1A;RHOA;MTOR;RHOB;CDC42;CAMSAP3;STMN1;FSCN1;PLXNB1;MAPK3
protein transport (GO:0015031),32/326,1.20E-05,0.000651612,2.29e+9,2.60e+9,ATP6V1A;NAPB;RAB5B;COPA;STX16;TIMM9;RAB1B;CLTC;VPS26A;AP2A1;VPS26B;HSP90B1;MYO6;APOE;ATP6V1C1;TBC1D10B;ATP6V0A1;ATP6V1F;NSF;ATP6V1G1;ATP6V1G2;PRKCB;STX8;AP3D1;RAB10;CTTN;RAB35;ATP6V1B2;RAB18;ATP6V0D1;ATP6V0C;VAMP2
positive regulation of dendritic spine development (GO:0060999),7/20,1.23E-05,0.000660179,8.17e+9,9.24e+9,CAMK2B;FMR1;CAPRIN1;APOE;SHANK3;SHANK2;SHANK1
ribosome biogenesis (GO:0042254),25/226,1.44E-05,0.000764805,2.58e+9,2.88e+7,RPL4;RPL5;RPL3;RPL32;RPLP1;RPL36A;RPL10A;RPL9;RPS14;RPL7A;RPS16;RPS19;RPL36;RPS11;RPL18;RPL17;RPS13;RPL19;RPS8;RPS5;RPS6;RPSA;RPL27A;RPS21;RAN
glucose metabolic process (GO:0006006),12/64,1.49E-05,0.000784998,4.38e+9,4.86e+9,GPI;TPI1;ALDH5A1;GOT1;MDH1;MDH2;GOT2;PGK1;ALDOC;ENO1;ENO2;PCK2
"Wnt signaling pathway, calcium modulating pathway (GO:0007223)",9/36,1.55E-05,0.000805831,5.83e+9,6.46e+9,GNAO1;PPP3CB;GNG2;AGO3;CAMK2A;GNB1;CTNNB1;PLCB1;CALM1
mitochondrial respiratory chain complex assembly (GO:0033108),15/97,1.55E-05,0.000799322,3.61e+9,4.00e+9,NDUFB9;NDUFA13;NDUFB7;NDUFA6;NDUFB10;UQCRB;NDUFB4;NDUFA10;SAMM50;NDUFS7;NDUFS3;NDUFS1;NDUFV3;NDUFV2;NDUFV1
regulation of actin cytoskeleton organization (GO:0032956),13/75,1.62E-05,0.000825491,4.05e+9,4.46e+9,DMTN;TWF2;TWF1;BAIAP2;CORO1A;RHOA;MTOR;RHOB;CDC42;ARHGDIB;FSCN1;PTK2B;PHPT1
mitochondrial ATP synthesis coupled proton transport (GO:0042776),7/21,1.78E-05,0.000897062,7.78e+8,8.51e+9,ATP5B;STOML2;ATP5A1;CYC1;ATP5F1;ATP5O;ATP5J2
regulation of axonogenesis (GO:0050770),11/55,1.78E-05,0.000891189,4.67e+9,5.10e+8,LINGO1;NTRK2;SIPA1L1;GDI1;CDH2;CTTN;PLXNB1;THY1;APOE;RHOA;PLXNA4
tRNA aminoacylation for protein translation (GO:0006418),10/46,1.98E-05,0.00098198,5.07e+8,5.49e+9,NARS;LRRC47;AIMP2;LARS;PPA1;RARS;SARS;IARS2;EPRS;AARS
"Wnt signaling pathway, planar cell polarity pathway (GO:0060071)",14/88,2.13E-05,0.001044549,3.71e+9,3.99e+9,PSMD12;CLTC;AP2A1;AP2B1;RHOA;CDC42;PSMB7;PSMD7;PSMC6;PSMD5;PSMB1;AP2S1;RAC1;AP2M1
positive regulation of telomerase RNA localization to Cajal body (GO:1904874),6/15,2.18E-05,0.001060753,9.33e+9,1.00e+9,CCT3;RUVBL2;TCP1;CCT8;CCT7;CCT5
insulin receptor signaling pathway (GO:0008286),12/67,2.42E-05,0.001165802,4.18e+9,4.44e+9,ATP6V1A;GSK3A;ATP6V1G1;ATP6V1G2;APC;ATP6V1B2;ATP6V0D1;BAIAP2;ATP6V0C;ATP6V1C1;ATP6V1F;ATP6V0A1
regulation of establishment of planar polarity (GO:0090175),14/89,2.43E-05,0.001157956,3.67e+9,3.90e+9,PSMD12;CLTC;AP2A1;AP2B1;RHOA;CDC42;PSMB7;PSMD7;PSMC6;PSMD5;PSMB1;AP2S1;RAC1;AP2M1
actin filament depolymerization (GO:0030042),5/10,3.01E-05,0.001420129,1.17e+9,1.21e+9,WDR1;CFL2;MICAL3;TWF2;TWF1
low-density lipoprotein particle receptor catabolic process (GO:0032802),5/10,3.01E-05,0.0014071,1.17e+9,1.21e+9,CLTC;AP2S1;AP2A1;AP2B1;AP2M1
purine ribonucleoside monophosphate biosynthetic process (GO:0009168),9/39,3.10E-05,0.001439806,5.39e+8,5.59e+9,ATP5B;ATIC;ATP5A1;GMPS;ATP5O;ATP5F1;PFAS;GART;ATP5J2
glycolytic process (GO:0006096),7/23,3.47E-05,0.001596342,7.10e+9,7.29e+9,PFKL;TPI1;PKM;PGK1;ENO2;PFKM;HK1
cell junction assembly (GO:0034329),11/59,3.56E-05,0.00162377,4.35e+9,4.46e+8,CDC42;CDH2;FSCN1;TBCD;CDH13;CTNNB1;PKP4;TLN2;TLN1;RHOA;ACTG1
regulation of dendritic spine development (GO:0060998),8/31,3.60E-05,0.001626941,6.02e+9,6.16e+9,CAMK2B;PTPRS;SIPA1L1;FMR1;APOE;SHANK3;SHANK2;SHANK1
tRNA aminoacylation (GO:0043039),9/40,3.85E-05,0.001725001,5.25e+9,5.34e+9,NARS;AIMP2;LARS;PPA1;RARS;SARS;IARS2;EPRS;AARS
"DNA-templated transcription, termination (GO:0006353)",15/106,4.54E-05,0.002015715,3.30e+9,3.30e+9,CPSF7;CHTOP;CPSF1;POLDIP3;CSTF2;DDX39B;PABPN1;POLR2A;SRSF3;SYMPK;SRSF4;RNPS1;SNRPD3;SRSF5;SRSF6
regulation of translation (GO:0006417),23/213,4.58E-05,0.002015626,2.52e+9,2.52e+9,CYFIP2;RPL5;MTPN;NUP107;DHX9;POLDIP3;FMR1;CIRBP;EPRS;LARP4;EEF2;ELAVL1;GIGYF2;MTOR;ATXN2;LARP1;POLR2A;CAPRIN1;EIF4H;VIM;EIF3D;EIF4B;RAN
negative regulation of cytoskeleton organization (GO:0051494),7/24,4.72E-05,0.00205932,6.81e+9,6.78e+9,TWF2;TWF1;CORO1A;SHANK3;SHANK1;PFN2;KANK3
ATP generation from ADP (GO:0006757),7/24,4.72E-05,0.002041869,6.81e+9,6.78e+9,PFKL;TPI1;PKM;PGK1;ENO2;PFKM;HK1
spliceosomal complex assembly (GO:0000245),9/41,4.75E-05,0.002037455,5.12e+8,5.10e+9,SART3;SNRPD2;DDX39B;SNRPD1;SNRPD3;SRSF5;PRPF19;SRSF6;SNRNP200
RNA export from nucleus (GO:0006405),16/119,4.85E-05,0.002063363,3.14e+9,3.12e+9,RANBP1;CHTOP;NUP107;RANBP3;CPSF1;POLDIP3;RPSA;DDX39B;HNRNPA2B1;SRSF3;SYMPK;SRSF4;RNPS1;SRSF5;SRSF6;RAN
positive regulation of cellular amide metabolic process (GO:0034250),11/61,4.92E-05,0.002076706,4.21e+9,4.17e+9,RPL5;GSK3A;POLDIP3;FMR1;CIRBP;VIM;LARP4;EEF2;ELAVL1;EIF3D;MTOR
actin cytoskeleton reorganization (GO:0031532),11/61,4.92E-05,0.002059684,4.21e+9,4.17e+9,NRP1;SIPA1L1;DMTN;CTTN;MINK1;RHOG;RAC1;FRY;EZR;CDC42BPA;RHOA
regulation of synaptic vesicle exocytosis (GO:2000300),6/17,5.01E-05,0.002079879,8.24e+9,8.15e+9,RIMS2;NAPB;RIMS1;STXBP1;FMR1;RAB3GAP1
2-oxoglutarate metabolic process (GO:0006103),6/17,5.01E-05,0.002063106,8.24e+9,8.15e+9,GOT1;IDH1;GOT2;IDH2;DLST;L2HGDH
positive regulation of actin filament polymerization (GO:0030838),10/51,5.12E-05,0.002089291,4.58e+9,4.52e+9,NCKAP1;CTTN;PRKCE;WIPF3;RHOG;PTK2B;ARPC4;RAC1;BAIAP2;PFN2
low-density lipoprotein receptor particle metabolic process (GO:0032799),5/11,5.32E-05,0.002152806,1.06e+9,1.04e+9,CLTC;AP2S1;AP2A1;AP2B1;AP2M1
Fc-gamma receptor signaling pathway involved in phagocytosis (GO:0038096),17/133,5.48E-05,0.002203626,2.98e+9,2.93e+9,CYFIP2;ACTR3;NCKAP1;ACTR2;HSP90AA1;HSP90AB1;PRKCE;WIPF3;ARPC1A;ARPC4;BAIAP2;ACTG1;IGHG3;NCKIPSD;CDC42;RAC1;MAPK3
establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197),8/33,5.88E-05,0.002342712,5.66e+9,5.51e+9,CDC42;CAMSAP3;WDR1;DLG3;SCRIB;LIN7C;LIN7B;RHOA
Fc-gamma receptor signaling pathway (GO:0038094),17/134,6.04E-05,0.002387396,2.96e+9,2.88e+7,CYFIP2;ACTR3;NCKAP1;ACTR2;HSP90AA1;HSP90AB1;PRKCE;WIPF3;ARPC1A;ARPC4;BAIAP2;ACTG1;IGHG3;NCKIPSD;CDC42;RAC1;MAPK3
regulation of lamellipodium assembly (GO:0010591),7/25,6.32E-05,0.00247938,6.53e+9,6.32e+9,CDC42;NCKAP1;DMTN;TWF2;FSCN1;TWF1;RAC1
cell morphogenesis involved in neuron differentiation (GO:0048667),14/97,6.48E-05,0.00252454,3.37e+9,3.25e+9,BRSK1;SPTBN4;LINGO1;FARP1;MINK1;TBCD;BAIAP2;RAB10;AFG3L2;MAP2;MAP1A;MAP6;MAP6D1;NEFH
Fc receptor mediated stimulatory signaling pathway (GO:0002431),17/135,6.63E-05,0.002564772,2.94e+9,2.83e+9,CYFIP2;ACTR3;NCKAP1;ACTR2;HSP90AA1;HSP90AB1;PRKCE;WIPF3;ARPC1A;ARPC4;BAIAP2;ACTG1;IGHG3;NCKIPSD;CDC42;RAC1;MAPK3
regulation of telomerase RNA localization to Cajal body (GO:1904872),6/18,7.25E-05,0.002780891,7.78e+8,7.42e+9,CCT3;RUVBL2;TCP1;CCT8;CCT7;CCT5
positive regulation of protein polymerization (GO:0032273),11/64,7.79E-05,0.002966986,4.01e+9,3.79e+9,NCKAP1;CLIP1;TPPP3;NUMA1;CTTN;PRKCE;RHOG;PTK2B;RAC1;BAIAP2;PFN2
membrane fusion (GO:0061025),10/54,8.53E-05,0.003225729,4.32e+9,4.05e+9,NSF;RIMS1;AFG3L2;NAPB;OPA1;MFF;GDAP1;VAMP2;VAMP3;VTI1B
microtubule cytoskeleton organization involved in mitosis (GO:1902850),9/44,8.57E-05,0.003214932,4.77e+8,4.47e+8,DYNC1H1;DCTN2;KIF3B;STMN1;RCC1;MAP4;KPNB1;RAN;CLASP2
regulation of focal adhesion assembly (GO:0051893),9/44,8.57E-05,0.003191466,4.77e+8,4.47e+8,CAMSAP3;NRP1;DMTN;THY1;RAC1;RHOA;SLC9A1;CORO1C;CLASP2
establishment of apical/basal cell polarity (GO:0035089),5/12,8.79E-05,0.003250712,9.72e+9,9.08e+9,CAMSAP3;CDC42;FSCN1;SCRIB;RHOA
actin filament bundle organization (GO:0061572),8/35,9.23E-05,0.003389421,5.33e+8,4.96e+9,DMTN;FSCN1;BAIAP2;EZR;RHOA;ADD2;PLS1;RHOB
positive regulation of excitatory postsynaptic potential (GO:2000463),6/19,0.000102102,0.003721621,7.37e+9,6.77e+9,RIMS2;RIMS1;PTK2B;SHANK3;SHANK2;SHANK1
"regulation of synaptic transmission, glutamatergic (GO:0051966)",9/45,0.00010307,0.003730259,4.67e+9,4.28e+9,ATAD1;UNC13A;CDH2;SYT1;PTK2B;ATP1A2;SHANK3;SHANK2;SHANK1
purine ribonucleotide metabolic process (GO:0009150),11/66,0.000104101,0.003741045,3.89e+9,3.57e+9,ACLY;HSPA8;HINT1;PODXL2;OPA1;NDUFS1;ATP1A2;BPNT1;ATP1B1;SULT4A1;RAN
positive regulation of translation (GO:0045727),12/78,0.000113916,0.004065132,3.59e+8,3.26e+9,RPL5;DHX9;POLDIP3;FMR1;HABP4;CIRBP;VIM;LARP4;EEF2;ELAVL1;EIF3D;MTOR
actin polymerization or depolymerization (GO:0008154),8/36,0.000114281,0.004049829,5.19e+9,4.71e+9,WDR1;COBLL1;CFL2;TWF2;MICAL3;TWF1;RAC1;CAP2
positive regulation of signaling (GO:0023056),8/36,0.000114281,0.004021899,5.19e+9,4.71e+9,RIMS2;NSF;RIMS1;SYT1;CLSTN1;SCRIB;SNCA;VAMP3
regulation of secretion by cell (GO:1903530),10/56,0.000117521,0.00410761,4.17e+9,3.77e+9,RIMS2;NSF;RAB10;RIMS1;SYT1;FMR1;CAMK2A;CPLX1;VAMP2;VAMP3
regulation of mRNA stability (GO:0043488),16/128,0.000117644,0.004083943,2.92e+9,2.64e+9,HSPA8;PSMD12;FMR1;CIRBP;ELAVL1;YWHAZ;GIGYF2;PSMB7;CARHSP1;PSMD7;LARP1;PSMC6;PSMD5;CSDC2;PSMB1;VIM
phosphate-containing compound metabolic process (GO:0006796),20/183,0.000119005,0.00410325,2.55e+9,2.30e+9,ISYNA1;EPHX2;PDXP;HDHD2;MTOR;PPP1CA;THTPA;PPM1A;PPP3CB;PFKL;TOLLIP;INPP5J;PGK1;PI4KA;PIP4K2A;ALDOC;CALM1;PLCB1;PFKM;MAPK3
cell-cell junction assembly (GO:0007043),12/79,0.000129161,0.00442356,3.54e+9,3.17e+9,GJA1;WDR1;CDH2;APC;FSCN1;CTNNA1;TBCD;CDH13;PKP4;TLN2;TLN1;RHOA
ion transport (GO:0006811),27/289,0.000130058,0.004424582,2.18e+9,1.95e+9,ATP6V1A;HCN4;SLC1A3;ATP2A2;ATP1A3;ATP1A2;SLC9A1;GJA1;ANXA6;SLC25A22;ATP6V1C1;ATP6V0A1;ATP6V1F;ATP6V1G1;ATP6V1G2;SLC12A5;ATP1B2;ATP2B1;ATP1B1;SLC25A18;ASPH;WNK1;ATP6V1B2;VDAC2;VDAC1;ATP6V0D1;ATP6V0C
tricarboxylic acid metabolic process (GO:0072350),5/13,0.000137816,0.004657463,8.98e+8,7.98e+9,ACLY;IDH3G;IDH1;IDH2;ACO2
positive regulation of lamellipodium assembly (GO:0010592),5/13,0.000137816,0.004626822,8.98e+8,7.98e+9,CDC42;NCKAP1;TWF2;FSCN1;RAC1
sodium ion export from cell (GO:0036376),5/13,0.000137816,0.004596582,8.98e+8,7.98e+9,ATP1A3;ATP1A2;ATP1B2;ATP1B1;SLC9A1
sodium ion export (GO:0071436),5/13,0.000137816,0.004566734,8.98e+8,7.98e+9,ATP1A3;ATP1A2;ATP1B2;ATP1B1;SLC9A1
cellular amino acid biosynthetic process (GO:0008652),7/28,0.000139042,0.004577615,5.83e+9,5.18e+9,OAT;GOT1;GOT2;BCAT1;GLUL;ASPA;GLS
aerobic respiration (GO:0009060),7/28,0.000139042,0.004548271,5.83e+9,5.18e+9,UQCRB;NDUFS7;MDH2;UQCRC1;MTFR1L;UQCRC2;SDHB
cell projection assembly (GO:0030031),6/20,0.000140593,0.004569725,7.00e+9,6.21e+8,CYFIP2;CDC42;NCKAP1;RHOG;RAC1;NEFH
neuron development (GO:0048666),17/144,0.00014861,0.004799713,2.76e+9,2.43e+9,NTRK2;FMR1;TBCD;HMGB1;FRY;PPP1R9A;CAMSAP1;PPP1R9B;MAP2;WNK1;STMN1;RAB35;PLP1;MAP4;NCDN;MAPRE2;SH3GL2
protein oligomerization (GO:0051259),22/217,0.000168154,0.005396785,2.37e+9,2.06e+9,MCCC2;MPP2;PRNP;CPSF7;STOML2;OAT;AHNAK;SYT1;ATPIF1;AKR1B1;MFF;SLC9A1;LETM1;GRHPR;PFKL;RPS19;OPA1;APC;LONP1;ANXA6;CHMP4B;PFKM
cellular response to hypoxia (GO:0071456),16/132,0.000169332,0.005400617,2.83e+9,2.46e+9,OPRD1;PSMD12;HP1BP3;FMN2;HIGD1A;MTOR;RBX1;NPEPPS;PSMB7;PSMD7;PSMC6;PSMD5;PSMB1;PGK1;UBQLN1;HYOU1
brain development (GO:0007420),15/119,0.000173145,0.005487946,2.94e+9,2.55e+9,NDRG4;SMG9;PTPN11;GRIN2B;CDH2;H2AFY2;PITPNM1;RAB18;PHGDH;CIC;SHANK3;SHANK2;PAFAH1B2;RAB3GAP1;SHANK1
protein alkylation (GO:0008213),7/29,0.000176552,0.005561396,5.63e+9,4.87e+9,EEF1A1;PCMT1;HSPA8;VCP;SNRPD3;EEF2;CALM1
cardiac muscle cell action potential (GO:0086001),7/29,0.000176552,0.005527277,5.63e+9,4.87e+9,HCN4;YWHAE;CACNA2D1;ATP1A2;DMD;ATP1B1;HCN2
protein localization to membrane (GO:0072657),18/160,0.000178014,0.005539048,2.63e+9,2.27e+8,SPTBN4;STXBP1;DENND4C;AP3D1;MYO5A;SCRIB;THY1;ATP1B1;LIN7C;LIN7B;RAB10;DLG3;HGS;CPE;EZR;AGRN;SHANK3;CLASP2
regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882),6/21,0.000189729,0.005867794,6.67e+9,5.71e+9,ATP2A2;ATP1A2;DMD;ATP1B1;CALM1;SLC9A1
positive regulation of lamellipodium organization (GO:1902745),6/21,0.000189729,0.005832445,6.67e+9,5.71e+9,CDC42;NCKAP1;TWF2;FSCN1;RAC1;CORO1C
branched-chain amino acid catabolic process (GO:0009083),6/21,0.000189729,0.005797521,6.67e+9,5.71e+9,MCCC2;HIBADH;AUH;DBT;BCAT1;HSD17B10
glutamate metabolic process (GO:0006536),6/21,0.000189729,0.005763011,6.67e+9,5.71e+9,OAT;ALDH5A1;GOT1;GOT2;GLUL;GLS
actin filament organization (GO:0007015),15/120,0.000190195,0.005742975,2.92e+9,2.50e+9,DMTN;RHOG;ARPC4;FRY;PPP1R9A;BAIAP2;RHOA;CD2AP;PPP1R9B;RHOB;CDC42;COBLL1;RAC1;PLS1;CAP2
regulation of heart contraction (GO:0008016),13/95,0.000202776,0.006086865,3.19e+9,2.72e+9,HCN4;GSK3A;AHCYL1;ATP2A2;ATP1A3;ATP1A2;ATP1B2;ATP2B1;ATP1B1;DES;ASPH;TH;CALM1
protein localization to endosome (GO:0036010),4/8,0.000204072,0.006089949,1.17e+9,9.91e+9,NRP1;TMEM30A;TOLLIP;RAB35
cell communication by electrical coupling involved in cardiac conduction (GO:0086064),5/14,0.000206832,0.00613643,8.33e+9,7.07e+9,GJA1;ATP1A3;ATP1A2;ATP1B2;ATP1B1
hydrogen peroxide catabolic process (GO:0042744),5/14,0.000206832,0.006100959,8.33e+9,7.07e+9,PRDX3;PRDX2;GPX1;PRDX1;PRDX6
ribonucleoside monophosphate biosynthetic process (GO:0009156),5/14,0.000206832,0.006065896,8.33e+9,7.07e+9,ATIC;RFK;GMPS;PFAS;GART
purine ribonucleoside monophosphate metabolic process (GO:0009167),8/39,0.000207368,0.006046838,4.79e+8,4.06e+9,HSPA8;ATIC;GMPS;ATP1A2;NDUFS1;ATP1B1;PFAS;GART
regulation of plasma membrane bounded cell projection assembly (GO:0120032),8/39,0.000207368,0.006012481,4.79e+8,4.06e+9,CDC42;ATG3;DMTN;FMR1;TWF2;FSCN1;TWF1;RAC1
monocarboxylic acid metabolic process (GO:0032787),14/108,0.000209684,0.006045304,3.03e+9,2.56e+8,MCCC2;ACOT7;PDHA1;SLC16A1;GOT2;PDHB;LDHB;GRHPR;SGPL1;ALDH5A1;FASN;PCCB;DLAT;PCK2
cellular response to organic cyclic compound (GO:0071407),16/135,0.000220113,0.006310311,2.77e+9,2.33e+9,HCN4;DMTN;AKR1B1;ATP1A3;PDXP;ATP1A2;HSP90B1;RAP1B;LARP1;GNG2;RUVBL2;GNB1;CTNNA1;CTNNB1;EZR;HCN2
regulation of actin cytoskeleton reorganization (GO:2000249),7/30,0.000221835,0.006324161,5.45e+9,4.58e+9,CDC42;NRP1;HAX1;ARHGDIB;PTK2B;BAIAP2;PHPT1
regulation of protein polymerization (GO:0032271),7/30,0.000221835,0.006289026,5.45e+9,4.58e+9,CAMSAP3;TPPP3;HAX1;MAP2;CAMSAP1;CAMSAP2;PFN2
axonogenesis (GO:0007409),22/223,0.000248172,0.006996803,2.30e+8,1.91e+9,CYFIP2;SPTBN4;NRP1;BRSK1;LINGO1;USP9X;PTPN11;BAIAP2;MLF2;RAB10;AFG3L2;PPP3CB;RPS6KA5;TUBB3;GPC1;MAP1A;TNR;PLXNB1;EZR;NEFH;SHANK3;MAPK3
cellular response to organonitrogen compound (GO:0071417),13/97,0.000250369,0.007019974,3.13e+9,2.59e+9,HCN4;DMTN;PDXP;MTOR;HSP90B1;RAP1B;LARP1;LARS;CTNNA1;CTNNB1;LAMTOR2;EZR;HCN2
branched-chain amino acid metabolic process (GO:0009081),6/22,0.000251472,0.007012371,6.36e+9,5.28e+8,MCCC2;HIBADH;AUH;DBT;BCAT1;HSD17B10
regulation of microtubule depolymerization (GO:0031114),6/22,0.000251472,0.00697426,6.36e+9,5.28e+8,CAMSAP3;APC;MAP1A;CAMSAP1;CAMSAP2;CLASP2
cellular response to peptide hormone stimulus (GO:0071375),14/110,0.000254758,0.007027185,2.97e+9,2.46e+9,GSK3A;GOT1;DENND4C;MYO5A;GNG12;ADCY8;RAB10;GNG3;PKM;GNG2;GNG5;GNB1;VAMP2;PCK2
dephosphorylation (GO:0016311),15/124,0.000273749,0.007510446,2.82e+9,2.32e+9,PTPRN2;PTPRS;PPP1R12A;EPHX2;PDXP;HDHD2;TIMM50;PPP1CA;THTPA;PPM1A;PPP5C;PPP3CB;PPP2R1A;SBF1;PHPT1
positive regulation of developmental growth (GO:0048639),9/51,0.000281198,0.007673538,4.12e+9,3.37e+7,RIMS2;RIMS1;UNC13A;SYT1;CPNE6;TWF2;PPIB;PLCB1;AGRN
mitotic spindle organization (GO:0007052),11/74,0.000296793,0.008056048,3.47e+9,2.82e+9,DYNC1H1;DCTN2;KIF3B;STMN1;RCC1;MAP4;RHOA;KPNB1;MAP9;RAN;CLASP2
cellular sodium ion homeostasis (GO:0006883),5/15,0.000299336,0.008082077,7.78e+8,6.31e+9,ATP1A3;ATP1A2;ATP1B2;ATP1B1;SLC9A1
transport along microtubule (GO:0010970),5/15,0.000299336,0.00803954,7.78e+8,6.31e+9,CDC42;CAMSAP3;HSPA8;DYNC1I2;DYNC1I1
regulation of cell size (GO:0008361),6/23,0.000327973,0.008762533,6.09e+9,4.88e+9,MTPN;LARS;AKT1S1;RAC1;RHOA;MTOR
positive regulation of establishment of protein localization to telomere (GO:1904851),4/9,0.000354869,0.00943174,1.04e+9,8.24e+9,TCP1;CCT8;CCT7;CCT5
potassium ion import across plasma membrane (GO:1990573),4/9,0.000354869,0.00938287,1.04e+9,8.24e+9,HCN4;ATP1A2;ATP1B1;HCN2
negative regulation of microtubule polymerization (GO:0031115),4/9,0.000354869,0.009334505,1.04e+9,8.24e+9,STMN1;TBCD;TUBB4A;SNCA
cytoskeletal anchoring at plasma membrane (GO:0007016),4/9,0.000354869,0.009286636,1.04e+9,8.24e+9,SPTBN4;TLN1;EZR;SHANK1
regulation of cell-substrate adhesion (GO:0010810),7/33,0.000416188,0.010835752,4.95e+9,3.85e+9,DMTN;MINK1;TBCD;THY1;RAC1;RHOA;CORO1C
cellular protein localization (GO:0034613),28/327,0.000417758,0.010821419,2.00e+9,1.55e+9,NAPB;RAB5B;COPA;STX16;RAB1B;CLTC;VPS26A;AP2A1;VPS26B;PRPF19;MYO6;DMD;TBC1D10B;NSF;STX8;AP3D1;WIPI2;SEPT3;RAB10;CTTN;HGS;CROCC;RAB35;RAB18;CTNNB1;CPE;LAMTOR2;EZR
dendritic spine morphogenesis (GO:0060997),5/16,0.0004201,0.01082713,7.29e+9,5.67e+9,CDC42;CTNND2;SHANK3;SHANK2;SHANK1
mitochondrial fusion (GO:0008053),5/16,0.0004201,0.010772722,7.29e+9,5.67e+9,AFG3L2;STOML2;OPA1;MFF;GDAP1
response to unfolded protein (GO:0006986),8/43,0.000420101,0.010718873,4.34e+9,3.38e+8,HSPA8;HSP90AA1;HSP90AB1;HSPA5;HSPA4;HYOU1;HSPA2;HSPE1
dendritic spine organization (GO:0097061),6/24,0.000421559,0.010702558,5.83e+9,4.53e+9,CDC42;PRNP;CTNND2;SHANK3;SHANK2;SHANK1
chaperone mediated protein folding requiring cofactor (GO:0051085),6/24,0.000421559,0.010649575,5.83e+9,4.53e+9,HSPA8;HSPA5;HSPA4;HYOU1;HSPA2;HSPE1
regulation of actin filament bundle assembly (GO:0032231),6/24,0.000421559,0.010597114,5.83e+9,4.53e+9,CDC42;RAC1;SHANK3;SLC9A1;SHANK1;PFN2
carboxylic acid biosynthetic process (GO:0046394),8/44,0.000494417,0.012367687,4.24e+9,3.23e+9,OAT;UGP2;GOT1;GOT2;ATPIF1;GLUL;ASPA;GLS
mRNA transport (GO:0051028),13/104,0.000499311,0.012429203,2.92e+9,2.22e+9,CHTOP;NUP107;CPSF1;POLDIP3;FMR1;DDX39B;HNRNPA2B1;SRSF3;SYMPK;SRSF4;RNPS1;SRSF5;SRSF6
positive regulation of telomere maintenance via telomere lengthening (GO:1904358),7/34,0.000504909,0.012507538,4.80e+9,3.65e+8,CCT3;TCP1;HNRNPA2B1;CCT8;CCT7;CCT5;MAPK3
plasma membrane bounded cell projection organization (GO:0120036),14/118,0.000527931,0.013014642,2.77e+9,2.09e+9,HMGB1;FRY;PPP1R9A;CAMSAP1;PPP1R9B;CTTN;MAP2;STMN1;RAB35;PLP1;MAP4;RAC1;NCDN;SH3GL2
lamellipodium organization (GO:0097581),6/25,0.000534737,0.013119052,5.60e+9,4.22e+9,ABLIM1;DMTN;ABLIM3;CTTN;CDH13;RAC1
modulation of excitatory postsynaptic potential (GO:0098815),6/25,0.000534737,0.013056281,5.60e+9,4.22e+9,RIMS2;RIMS1;PTK2B;SHANK3;SHANK2;SHANK1
protein depolymerization (GO:0051261),6/25,0.000534737,0.012994109,5.60e+9,4.22e+9,WDR1;CFL2;STMN1;TWF2;MICAL3;TWF1
mRNA export from nucleus (GO:0006406),13/105,0.000547967,0.013252494,2.89e+9,2.17e+9,CHTOP;NUP107;CPSF1;POLDIP3;DDX39B;PABPN1;HNRNPA2B1;SRSF3;SYMPK;SRSF4;RNPS1;SRSF5;SRSF6
nuclear export (GO:0051168),12/92,0.000550692,0.013255579,3.04e+9,2.28e+9,RANBP1;CHTOP;RANBP3;DDX39B;POLDIP3;SRSF3;NUTF2;SRSF4;RNPS1;SRSF5;SRSF6;RAN
positive regulation of receptor recycling (GO:0001921),4/10,0.000571412,0.013689742,9.33e+9,6.97e+9,NSF;SCRIB;SNCA;VAMP3
regulation of histone phosphorylation (GO:0033127),4/10,0.000571412,0.013625771,9.33e+9,6.97e+9,RPS6KA5;H2AFY;FMR1;MAPK3
regulation of establishment of protein localization to telomere (GO:0070203),4/10,0.000571412,0.013562395,9.33e+9,6.97e+9,TCP1;CCT8;CCT7;CCT5
polarized epithelial cell differentiation (GO:0030859),4/10,0.000571412,0.013499606,9.33e+9,6.97e+9,RAB10;CDC42;CAMSAP3;RHOA
endothelial tube morphogenesis (GO:0061154),4/10,0.000571412,0.013437396,9.33e+9,6.97e+9,CSNK2B;CTNNB1;RHOA;RHOB
L-glutamate transport (GO:0015813),4/10,0.000571412,0.013375757,9.33e+9,6.97e+9,SLC25A18;PRAF2;SLC1A3;SLC25A22
positive regulation of dendrite extension (GO:1903861),5/17,0.000574254,0.013380916,6.86e+8,5.12e+9,RIMS2;RIMS1;UNC13A;SYT1;CPNE6
virion assembly (GO:0019068),5/17,0.000574254,0.013320094,6.86e+8,5.12e+9,RAB1B;VTA1;CHMP4B;APOE;PPIA
regulation of lamellipodium organization (GO:1902743),5/17,0.000574254,0.013259822,6.86e+8,5.12e+9,CDC42;DMTN;TWF2;TWF1;RAC1
cellular monovalent inorganic cation homeostasis (GO:0030004),5/17,0.000574254,0.013200093,6.86e+8,5.12e+9,ATP1A3;ATP1A2;ATP1B2;ATP1B1;SLC9A1
regulation of neuron projection development (GO:0010975),14/119,0.000575236,0.013163353,2.75e+9,2.05e+9,CAMK2B;NTRK2;NDRG4;PTPRS;KIDINS220;TWF2;TWF1;CRMP1;CAMSAP2;SIPA1L1;CDH2;NPTN;PTK2B;APOE
nicotinamide nucleotide metabolic process (GO:0046496),8/45,0.000579033,0.013191084,4.15e+9,3.09e+9,PFKL;TPI1;PKM;PGK1;PDHB;ENO2;PFKM;HK1
positive regulation of ATPase activity (GO:0032781),7/35,0.000608056,0.013790716,4.67e+9,3.46e+9,DYNC1I2;CHTOP;DHX9;ATP1B2;ATP1B1;DYNC1I1;PFN2
carbohydrate catabolic process (GO:0016052),7/35,0.000608056,0.013729695,4.67e+9,3.46e+9,PFKL;TPI1;PKM;PGK1;ENO2;PFKM;HK1
regulated exocytosis (GO:0045055),16/148,0.000622524,0.013994458,2.52e+9,1.86e+9,WDR1;AHSG;STXBP1;PCDH7;TUBA4A;RIMS2;RIMS1;ISLR;PPP3CB;ALB;HABP4;PHACTR2;TLN1;CALM1;VAMP2;VTI1B
protein catabolic process (GO:0030163),11/81,0.000656208,0.014686961,3.17e+9,2.32e+9,PSMB7;HSPA8;HSP90AA1;VCP;FBXO2;PSMB1;APOE;PRPF19;CTSD;CLN6;MTOR
regulation of G2/M transition of mitotic cell cycle (GO:0010389),16/149,0.000670333,0.014937586,2.51e+8,1.83e+9,YWHAE;DYNC1I2;DYNC1H1;PSMD12;HSP90AA1;DCTN2;TUBB4A;TUBA4A;RBX1;PSMB7;ACTR1A;PSMD7;PSMC6;PPP2R1A;PSMD5;PSMB1
protein methylation (GO:0006479),8/46,0.000674972,0.014975582,4.06e+9,2.96e+8,EEF1A1;PCMT1;HSPA8;VCP;CARM1;SNRPD3;EEF2;CALM1
positive regulation of plasma membrane bounded cell projection assembly (GO:0120034),10/69,0.00067979,0.015017184,3.38e+9,2.47e+9,CDC42;NRP1;NCKAP1;APC;FMR1;CROCC;FSCN1;TWF2;RAC1;AGRN
modulation of chemical synaptic transmission (GO:0050804),11/82,0.000729085,0.016036736,3.13e+9,2.26e+9,RIMS2;RIMS1;UNC13A;CDH2;SYT1;FMR1;CLSTN1;CAMK2A;EIF4EBP2;ATP1A2;CPLX1
interleukin-1-mediated signaling pathway (GO:0070498),12/95,0.000738072,0.016164736,2.95e+9,2.13e+8,PSMB7;PSMD12;PSMD7;RPS6KA5;PSMC6;PSMD5;TOLLIP;PSMB1;UBE2V1;PLCB1;RBX1;MAPK3
ER to Golgi vesicle-mediated transport (GO:0006888),18/180,0.000748852,0.016330731,2.33e+9,1.68e+9,NSF;DCTN6;SPTBN4;TRAPPC3;DYNC1I2;DYNC1H1;COPA;SEC23A;DCTN2;RAB1B;ARFGAP2;ACTR1A;RAB35;CAPZA2;HYOU1;ACTR10;DYNC1I1;VTI1B
positive regulation of cell morphogenesis involved in differentiation (GO:0010770),9/58,0.000753415,0.01636033,3.62e+9,2.60e+9,CDC42;NRP1;NTRK2;DMTN;CAPRIN1;PLXNB1;RAC1;RHOA;PLXNA4
vascular endothelial growth factor receptor signaling pathway (GO:0048010),10/70,0.000763174,0.016502026,3.33e+9,2.39e+9,CYFIP2;CDC42;NRP1;NCKAP1;HSP90AA1;PTK2B;RAC1;BAIAP2;RHOA;ACTG1
negative regulation of RNA splicing (GO:0033119),5/18,0.000767246,0.016520074,6.48e+9,4.65e+9,RNPS1;SRSF4;SRSF6;PTBP2;RPS13
negative regulation of microtubule depolymerization (GO:0007026),5/18,0.000767246,0.016450662,6.48e+9,4.65e+9,CAMSAP3;APC;CAMSAP1;CAMSAP2;CLASP2
regulation of dendrite extension (GO:1903859),5/18,0.000767246,0.01638183,6.48e+9,4.65e+9,RIMS2;RIMS1;UNC13A;SYT1;CPNE6
nuclear import (GO:0051170),10/71,0.000854794,0.018175065,3.29e+9,2.32e+9,PDIA3;RANBP1;NUP107;RANBP3;SNRPD2;SNRPD1;NUTF2;SNRPD3;KPNB1;RAN
spliceosomal snRNP assembly (GO:0000387),7/37,0.00086418,0.018298379,4.42e+9,3.11e+9,SART3;SNRPD2;SNRPD1;STRAP;SNRPD3;PRPF19;PRPF8
import across plasma membrane (GO:0098739),4/11,0.00086756,0.018294047,8.49e+9,5.98e+9,HCN4;ATP1A2;ATP1B1;HCN2
regulation of long-term neuronal synaptic plasticity (GO:0048169),4/11,0.00086756,0.018218762,8.49e+9,5.98e+9,CAMK2B;NPTN;SYP;SHANK3
regulation of actin filament depolymerization (GO:0030834),4/11,0.00086756,0.018144095,8.49e+9,5.98e+9,MTPN;WDR1;CFL2;PDXP
calcium ion regulated exocytosis (GO:0017156),4/11,0.00086756,0.018070038,8.49e+9,5.98e+9,RIMS2;RIMS1;PPP3CB;VAMP2
"positive regulation of protein localization to chromosome, telomeric region (GO:1904816)",4/11,0.00086756,0.017996582,8.49e+9,5.98e+9,TCP1;CCT8;CCT7;CCT5
cytoplasmic microtubule organization (GO:0031122),8/48,0.000905206,0.018701492,3.89e+9,2.73e+9,ATAD1;CAMSAP3;DYNC1H1;NUMA1;EZR;CAMSAP1;KPNB1;CAMSAP2
protein dephosphorylation (GO:0006470),14/125,0.00094128,0.019368345,2.61e+9,1.82e+9,PTPRN2;PTPRS;PPP1R12A;PDXP;PTPN11;PPM1E;TIMM50;PPP1CA;PPM1A;PPP5C;PPP3CB;PPP2R1A;SBF1;PHPT1
regulation of stress fiber assembly (GO:0051492),9/60,0.000969188,0.019862517,3.50e+9,2.43e+9,CDC42;NRP1;STMN1;RAC1;PPM1E;RHOA;PFN2;SLC9A1;CLASP2
regulation of cellular component organization (GO:0051128),15/140,0.000997446,0.020359873,2.50e+9,1.73e+9,HSPA8;RAB5B;HSP90AA1;PTPN11;LARP4;CAMSAP1;MTOR;CAMSAP2;RAP1B;CAMSAP3;KIAA1109;AAK1;AP2S1;CDH13;LAMTOR2
cytoskeleton organization (GO:0007010),14/126,0.001018158,0.020699846,2.59e+9,1.79e+9,SPTBN4;DMTN;MICAL3;THY1;LARP4;CAMSAP1;NCKIPSD;CDC42;DES;PTK2B;APOE;TLN1;EZR;SHANK1
regulation of defense response to virus by virus (GO:0050690),6/28,0.001019377,0.020642385,5.00e+9,3.44e+9,AP2S1;AP1S1;AP2A1;RAC1;AP2B1;AP2M1
neuron projection extension (GO:1990138),6/28,0.001019377,0.020560795,5.00e+9,3.44e+9,NRP1;PPP3CB;USP9X;CTNNB1;PLXNB1;SH3GL2
establishment of protein localization to mitochondrion (GO:0072655),8/49,0.001041834,0.020931011,3.81e+9,2.62e+9,TIMM10B;TIMM9;AIP;TOMM34;MFF;GDAP1;HK1;TIMM50
positive regulation of macromolecule biosynthetic process (GO:0010557),15/142,0.001153433,0.023082222,2.47e+9,1.67e+9,RPL5;MTPN;DHX9;POLDIP3;FMR1;CIRBP;AKR1B1;LARP4;EEF2;ELAVL1;MTOR;NAMPT;VIM;EIF3D;RAB3GAP1
mRNA-containing ribonucleoprotein complex export from nucleus (GO:0071427),12/100,0.00116764,0.023275254,2.80e+9,1.89e+8,CHTOP;NUP107;DDX39B;CPSF1;POLDIP3;HNRNPA2B1;SRSF3;SYMPK;SRSF4;RNPS1;SRSF5;SRSF6
fatty acid beta-oxidation (GO:0006635),8/50,0.001194449,0.023717016,3.73e+9,2.51e+9,HADHB;HADHA;ECHS1;AUH;SCP2;ECI1;ETFDH;HSD17B4
acyl-CoA metabolic process (GO:0006637),7/39,0.001198569,0.023706578,4.19e+8,2.82e+9,ACOT7;SUCLA2;DBT;ACSL6;DLST;DBI;SUCLG1
clathrin-dependent endocytosis (GO:0072583),7/39,0.001198569,0.023615046,4.19e+8,2.82e+9,SYT1;CLTC;AP2S1;AP2A1;AP2B1;AP2M1;SNCA
regulation of actin filament-based process (GO:0032970),9/62,0.001232524,0.024190657,3.39e+9,2.27e+9,CDC42;DMTN;FSCN1;TWF2;BAIAP2;CORO1A;RHOA;MTOR;RHOB
establishment of protein localization to organelle (GO:0072594),9/62,0.001232524,0.024097973,3.39e+9,2.27e+9,PDIA3;RANBP1;NUP107;RANBP3;NUTF2;SCRIB;KPNB1;RAN;HK1
positive regulation of histone modification (GO:0031058),6/29,0.001239245,0.024136904,4.83e+9,3.23e+9,CHTOP;RPS6KA5;SART3;FMR1;RUVBL2;MAPK3
positive regulation of establishment of protein localization (GO:1904951),4/12,0.001257388,0.024397151,7.78e+8,5.20e+9,TCP1;CCT8;CCT7;CCT5
serine family amino acid biosynthetic process (GO:0009070),4/12,0.001257388,0.024304737,7.78e+8,5.20e+9,MTHFD1;PHGDH;SEPHS1;SEPHS2
cytoplasmic translational initiation (GO:0002183),4/12,0.001257388,0.024213021,7.78e+8,5.20e+9,EIF3M;EIF4H;EIF3D;EIF4B
purine nucleoside monophosphate biosynthetic process (GO:0009127),4/12,0.001257388,0.024121995,7.78e+8,5.20e+9,ATIC;GMPS;PFAS;GART
hydrogen peroxide metabolic process (GO:0042743),5/20,0.001292869,0.024709773,5.83e+9,3.88e+9,PRDX3;PRDX2;GPX1;PRDX1;PRDX6
negative regulation of protein depolymerization (GO:1901880),5/20,0.001292869,0.024617572,5.83e+9,3.88e+9,CAMSAP3;APC;CAMSAP1;CAMSAP2;CLASP2
cellular protein complex assembly (GO:0043623),15/144,0.001329469,0.02522038,2.43e+9,1.61e+9,HSP90AA1;NUP107;HSP90AB1;HSPA4;CLTC;TBCD;RBX1;SEPT3;CAND1;SAMM50;TCP1;LONP1;AP2S1;EIF4H;EIF4B
regulation of exocytosis (GO:0017157),8/51,0.001364357,0.025786343,3.66e+9,2.42e+9,RIMS2;NSF;RAB10;SYT1;CPLX1;VAMP2;SNCA;CLASP2
positive regulation of cell projection organization (GO:0031346),9/63,0.001384292,0.026066583,3.33e+9,2.19e+9,CAMK2B;NTRK2;NDRG4;KIDINS220;NPTN;TWF2;TWF1;PTK2B;APOE
astral microtubule organization (GO:0030953),3/6,0.001422643,0.026690255,1.17e+9,7.65e+9,NUMA1;EZR;KPNB1
acetyl-CoA biosynthetic process (GO:0006085),3/6,0.001422643,0.026592488,1.17e+9,7.65e+9,ACLY;PDHA1;PDHB
positive regulation of histone phosphorylation (GO:0033129),3/6,0.001422643,0.026495435,1.17e+9,7.65e+9,RPS6KA5;FMR1;MAPK3
morphogenesis of an endothelium (GO:0003159),3/6,0.001422643,0.026399088,1.17e+9,7.65e+9,CSNK2B;CTNNB1;RHOB
succinyl-CoA metabolic process (GO:0006104),3/6,0.001422643,0.026303439,1.17e+9,7.65e+9,SUCLA2;DLST;SUCLG1
Golgi vesicle transport (GO:0048193),23/271,0.001480005,0.027265213,1.98e+9,1.29e+9,NSF;DCTN6;SPTBN4;DYNC1I2;DYNC1H1;TRAPPC3;COPA;SEC23A;DCTN2;RAB1B;MYO5A;SCAMP3;ARFGAP2;ACTR1A;KIF3B;CAPZA2;RAB35;HYOU1;ACTR10;VAMP2;DYNC1I1;ATP9A;VTI1B
'de novo' posttranslational protein folding (GO:0051084),6/30,0.001493599,0.027416673,4.67e+9,3.04e+9,HSPA8;HSPA5;HSPA4;HYOU1;HSPA2;HSPE1
negative regulation of cell morphogenesis involved in differentiation (GO:0010771),6/30,0.001493599,0.027318405,4.67e+9,3.04e+9,LINGO1;DMTN;GDI1;THY1;RHOA;CORO1C
regulation of cell-matrix adhesion (GO:0001952),8/52,0.001552914,0.02830186,3.59e+8,2.32e+9,CAMSAP3;MINK1;CDH13;PTK2B;THY1;RHOA;SLC9A1;CORO1C
mitochondrial fission (GO:0000266),5/21,0.001637602,0.029739077,5.56e+9,3.56e+9,OPA1;MTFR1L;MFF;GDAP1;SLC25A46
"mitochondrial electron transport, cytochrome c to oxygen (GO:0006123)",5/21,0.001637602,0.029633619,5.56e+9,3.56e+9,NDUFA4;COX4I1;CYCS;COX6C;COX6B1
peptide metabolic process (GO:0006518),12/104,0.001644941,0.029661243,2.69e+9,1.73e+9,EEF1G;NPEPPS;HSPA8;HSP90AA1;GPX1;ALDH5A1;GDAP1L1;CPE;LNPEP;DMD;LTA4H;GDAP1
cellular potassium ion homeostasis (GO:0030007),4/13,0.001754978,0.031533984,7.18e+8,4.56e+8,ATP1A3;ATP1A2;ATP1B2;ATP1B1
dicarboxylic acid catabolic process (GO:0043649),4/13,0.001754978,0.031423339,7.18e+8,4.56e+8,GOT1;GOT2;GLUL;ASPA
regulation of neurotransmitter transport (GO:0051588),4/13,0.001754978,0.031313467,7.18e+8,4.56e+8,RIMS1;FMR1;CAMK2A;CPLX1
regulation of cellular response to heat (GO:1900034),10/78,0.001780875,0.031664822,2.99e+8,1.89e+9,YWHAE;CAMK2B;HSPA8;HSP90AA1;NUP107;HSP90AB1;AKT1S1;CAMK2A;MTOR;MAPK3
cellular response to unfolded protein (GO:0034620),5/22,0.002045288,0.036239951,5.30e+9,3.28e+8,HSPA8;HSPA5;HSPA4;HYOU1;HSPA2
endosomal transport (GO:0016197),20/229,0.00209314,0.0369595,2.04e+9,1.26e+9,STX16;STX8;VTA1;CLTC;SCRIB;VPS26A;AP2A1;VPS26B;DCLK1;RHOB;RAB10;HGS;VPS53;RAB35;CHMP4B;UBE2O;SNX5;TBC1D10B;VTI1B;VAMP3
negative regulation of calcium ion transmembrane transporter activity (GO:1901020),6/32,0.002119382,0.037293821,4.38e+9,2.69e+9,YWHAE;FMR1;UBQLN1;ATP1A2;GNB5;CALM1
cellular response to glucagon stimulus (GO:0071377),6/32,0.002119382,0.037165664,4.38e+9,2.69e+9,GNG3;GNG2;GNG5;GNB1;ADCY8;GNG12
ATP biosynthetic process (GO:0006754),6/32,0.002119382,0.037038384,4.38e+9,2.69e+9,ATP5B;ATP5A1;ATP5O;ATP5F1;ATP6V0A1;ATP5J2
purine ribonucleoside triphosphate metabolic process (GO:0009205),6/32,0.002119382,0.036911973,4.38e+9,2.69e+9,HSPA8;OPA1;ATP1A2;NDUFS1;ATP1B1;RAN
positive regulation of telomere maintenance via telomerase (GO:0032212),6/32,0.002119382,0.036786422,4.38e+9,2.69e+9,CCT3;TCP1;CCT8;CCT7;CCT5;MAPK3
positive regulation of dendrite development (GO:1900006),6/32,0.002119382,0.036661722,4.38e+9,2.69e+9,FMR1;CAPRIN1;APOE;SHANK3;SHANK2;SHANK1
regulation of cardiac conduction (GO:1903779),9/67,0.00214841,0.037038304,3.13e+9,1.93e+9,AHCYL1;ASPH;ATP2A2;ATP1A3;ATP1A2;ATP1B2;ATP2B1;ATP1B1;CALM1
intracellular protein transport (GO:0006886),27/347,0.002159496,0.037104063,1.82e+9,1.11e+9,OPRD1;NAPB;RAB5B;COPA;NUP107;STX16;RAB1B;CLTC;VPS26A;AP2A1;VPS26B;MYO6;TBC1D10B;PDIA3;NSF;RANBP1;RANBP3;STX8;AP3D1;NUTF2;CAMSAP3;RAB10;CTTN;RAB35;RAB18;KPNB1;RAN
regulation of multicellular organismal development (GO:2000026),7/43,0.00216496,0.037073118,3.80e+9,2.33e+9,PHLDB1;KIAA1109;GPX1;TRIP12;HMGB1;FGF1;CLASP2
protein transmembrane import into intracellular organelle (GO:0044743),7/43,0.00216496,0.036949127,3.80e+9,2.33e+9,NDUFA13;HSP90AA1;SAMM50;TIMM29;HSPA4;TIMM9;TIMM50
positive regulation of DNA biosynthetic process (GO:2000573),8/55,0.002244811,0.038184235,3.39e+9,2.07e+9,CCT3;HSP90AA1;HSP90AB1;TCP1;CCT8;CCT7;CCT5;MAPK3
muscle contraction (GO:0006936),14/137,0.002272384,0.038524838,2.38e+9,1.45e+9,GAMT;HCN4;DTNA;GNAO1;GJA1;MYL6;DES;ASPH;PABPN1;DMD;VIM;TLN1;CALM1;SNTA1
regulation of Golgi organization (GO:1903358),4/14,0.002374239,0.040118344,6.67e+9,4.03e+8,CAMSAP3;MAP2K1;CAMSAP2;MAPK3
negative regulation of T cell receptor signaling pathway (GO:0050860),4/14,0.002374239,0.039985941,6.67e+9,4.03e+8,PRNP;THY1;PHPT1;EZR
protein localization to basolateral plasma membrane (GO:1903361),3/7,0.002410413,0.040461638,1.00e+9,6.03e+8,RAB10;LIN7C;LIN7B
postsynaptic density assembly (GO:0097107),3/7,0.002410413,0.040328977,1.00e+9,6.03e+8,SHANK3;SHANK2;SHANK1
protein import into mitochondrial inner membrane (GO:0045039),3/7,0.002410413,0.040197183,1.00e+9,6.03e+8,NDUFA13;TIMM29;TIMM9
outer mitochondrial membrane organization (GO:0007008),3/7,0.002410413,0.040066248,1.00e+9,6.03e+8,HSP90AA1;SAMM50;HSPA4
response to increased oxygen levels (GO:0036296),3/7,0.002410413,0.039936163,1.00e+9,6.03e+8,ATP6V1A;ATP6V1G1;ATP6V0D1
malate metabolic process (GO:0006108),3/7,0.002410413,0.039806919,1.00e+9,6.03e+8,FH;MDH1;MDH2
regulation of dendritic spine maintenance (GO:1902950),3/7,0.002410413,0.03967851,1.00e+9,6.03e+8,PRNP;APOE;GRIN2B
regulation of vesicle-mediated transport (GO:0060627),14/138,0.002431886,0.039903256,2.37e+9,1.43e+9,NSF;NRP1;MAP2K1;RAB5B;SYT1;CPLX1;RIMS2;RAB10;AAK1;AP2S1;CDH13;VAMP2;TBC1D10B;MAPK3
adherens junction organization (GO:0034332),7/44,0.002481009,0.040578816,3.71e+9,2.23e+9,CADM3;CDH2;CADM2;CTNNA1;TBCD;CDH13;CTNNB1
lamellipodium assembly (GO:0030032),5/23,0.002522322,0.041122716,5.07e+8,3.04e+9,ABLIM1;DMTN;ABLIM3;CDH13;RAC1
negative regulation of axonogenesis (GO:0050771),5/23,0.002522322,0.040991752,5.07e+8,3.04e+9,LINGO1;PTPRS;GDI1;THY1;RHOA
regulation of monooxygenase activity (GO:0032768),5/23,0.002522322,0.040861619,5.07e+8,3.04e+9,HSP90AA1;SPR;CALM1;CYGB;SNCA
cellular response to catecholamine stimulus (GO:0071870),5/23,0.002522322,0.04073231,5.07e+8,3.04e+9,GNG2;GNB1;SLC9A1;MAPK3;SNCA
TOR signaling (GO:0031929),5/23,0.002522322,0.040603817,5.07e+8,3.04e+9,LARP1;RPS6;AKT1S1;EIF4EBP2;MTOR
organonitrogen compound catabolic process (GO:1901565),8/56,0.002522533,0.040479513,3.33e+9,1.99e+9,NPEPPS;SGPL1;TST;LNPEP;LTA4H;CTSD;CLN6;MTOR
protein import (GO:0017038),8/56,0.002522533,0.040352618,3.33e+9,1.99e+9,PDIA3;RANBP1;NUP107;RANBP3;NUTF2;APOE;KPNB1;RAN
"retrograde transport, endosome to Golgi (GO:0042147)",10/82,0.00259801,0.041430146,2.85e+9,1.69e+9,STX16;VPS53;CLTC;UBE2O;VPS26A;VPS26B;SNX5;TBC1D10B;VAMP3;VTI1B
apoptotic mitochondrial changes (GO:0008637),6/34,0.002924936,0.046498281,4.12e+9,2.40e+9,ATG3;CAMK2A;NDUFS1;MFF;SOD2;TIMM50
response to glucagon (GO:0033762),6/34,0.002924936,0.046353876,4.12e+9,2.40e+9,GNG3;GNG2;GNG5;GNB1;ADCY8;GNG12
positive regulation of hydrolase activity (GO:0051345),16/172,0.003015118,0.04763513,2.17e+9,1.26e+9,NDUFA13;VCP;CHTOP;ATP1B2;THY1;ATP1B1;RHOA;LARS;PKP4;PLXNB1;GNB5;CALM1;AGRN;RAB3GAP1;RGS7;PFN2
receptor catabolic process (GO:0032801),5/24,0.003075157,0.048433717,4.86e+9,2.81e+9,CLTC;AP2S1;AP2A1;AP2B1;AP2M1
regulation of neuronal synaptic plasticity (GO:0048168),5/24,0.003075157,0.04828469,4.86e+9,2.81e+9,CAMK2B;CAMK2A;SYP;APOE;RAB3GAP1
regulation of cell cycle G2/M phase transition (GO:1902749),10/84,0.003106393,0.04862553,2.78e+9,1.60e+9,YWHAE;DYNC1I2;DYNC1H1;ACTR1A;HSP90AA1;H2AFY;DCTN2;PPP2R1A;TUBB4A;TUBA4A
L-alpha-amino acid transmembrane transport (GO:1902475),4/15,0.003128752,0.04882575,6.22e+9,3.59e+9,SLC7A5;SLC25A18;SLC1A3;SLC25A22
regulation of cell-substrate junction assembly (GO:0090109),4/15,0.003128752,0.048676891,6.22e+9,3.59e+9,CAMSAP3;RHOA;SLC9A1;CORO1C
positive regulation of phosphoprotein phosphatase activity (GO:0032516),4/15,0.003128752,0.048528937,6.22e+9,3.59e+9,PPP1R12A;HSP90AB1;CALM1;MTOR
establishment of protein localization to endoplasmic reticulum (GO:0072599),4/15,0.003128752,0.04838188,6.22e+9,3.59e+9,RAB10;PMM1;SRP14;RAB3GAP1
post-Golgi vesicle-mediated transport (GO:0006892),8/58,0.003158099,0.048688161,3.22e+9,1.85e+9,RAB10;EXOC6B;AP3D1;MYO5A;AP2A1;SCAMP3;VAMP2;VTI1B
mitotic cell cycle phase transition (GO:0044772),19/221,0.003180756,0.048889759,2.01e+9,1.15e+8,YWHAE;DYNC1I2;RANBP1;DYNC1H1;HSP90AA1;RANBP3;PPP1R12A;DCTN2;CAMK2A;TUBB4A;TUBA4A;ACTR1A;PPP2R1A;PPME1;RCC1;CHMP4B;PLCB1;BCAT1;CLASP2
regulation of cation channel activity (GO:2001257),9/71,0.00321575,0.049279193,2.96e+9,1.70e+9,AHNAK;MINK1;PTK2B;DMD;CALM1;SHANK3;SHANK2;VAMP2;SHANK1
"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (GO:0000462)",6/35,0.003404292,0.05201228,4.00e+9,2.27e+9,RPS14;RPS16;RPS19;RPS8;RPSA;RPS21
regulation of mitochondrial membrane potential (GO:0051881),6/35,0.003404292,0.051857019,4.00e+9,2.27e+9,OPRD1;PRDX3;STOML2;VCP;ATPIF1;NDUFS1
regulation of phosphoprotein phosphatase activity (GO:0043666),6/35,0.003404292,0.051702683,4.00e+9,2.27e+9,PPP1R2;HSP90AB1;PPP1R12A;CALM1;MTOR;HSP90B1
regulation of cardiac muscle contraction (GO:0055117),6/35,0.003404292,0.051549262,4.00e+9,2.27e+9,HCN4;CHGA;ATP2A2;ATP1B1;CALM1;SLC9A1
cell morphogenesis (GO:0000902),8/59,0.003519247,0.053132299,3.16e+9,1.79e+9,CYFIP2;NCKAP1;CDH2;RHOG;CDH13;RAC1;FRY;CAP2
cell-cell junction organization (GO:0045216),9/72,0.003538678,0.053268071,2.92e+9,1.65e+9,CADM3;CDH2;CADM2;FSCN1;CTNNA1;CDH13;PKP4;TLN2;TLN1
transmembrane transport (GO:0055085),28/378,0.003634504,0.054549625,1.73e+9,9.71e+9,ATP6V1A;VCP;PSMD12;ATP2A2;ATP1A3;ATP1A2;ADD2;PSMB7;GJA1;PSMD7;PSMD5;PSMB1;ANXA6;ATP6V1C1;ATP6V0A1;ATP6V1F;ATP6V1G1;ATP6V1G2;DMTN;TMEM30A;ATP1B2;ATP2B1;ATP1B1;PSMC6;ASPH;ATP6V1B2;ATP6V0D1;ATP6V0C
cellular response to heat (GO:0034605),7/47,0.003644567,0.054540246,3.48e+9,1.95e+9,YWHAE;HSPA8;HSPA5;HSPA4;HYOU1;HSPA2;FGF1
positive regulation of filopodium assembly (GO:0051491),5/25,0.003710264,0.05536104,4.67e+9,2.61e+9,CDC42;NRP1;FMR1;FSCN1;AGRN
potassium ion homeostasis (GO:0055075),5/25,0.003710264,0.055199638,4.67e+9,2.61e+9,SLC12A5;ATP1A3;ATP1A2;ATP1B2;ATP1B1
TORC1 signaling (GO:0038202),3/8,0.003734224,0.055394607,8.75e+9,4.89e+9,LARP1;AKT1S1;MTOR
establishment of protein localization to chromatin (GO:0071169),3/8,0.003734224,0.055234043,8.75e+9,4.89e+9,H2AFY;H2AFY2;RUVBL2
alpha-amino acid biosynthetic process (GO:1901607),3/8,0.003734224,0.055074407,8.75e+9,4.89e+9,GAMT;MTHFD1;BCAT1
succinate metabolic process (GO:0006105),3/8,0.003734224,0.054915692,8.75e+9,4.89e+9,ALDH5A1;SUCLG1;SDHA
barbed-end actin filament capping (GO:0051016),3/8,0.003734224,0.054757888,8.75e+9,4.89e+9,TWF2;TWF1;ADD2
regulation of chaperone-mediated autophagy (GO:1904714),3/8,0.003734224,0.054600988,8.75e+9,4.89e+9,EEF1A1;EEF1A2;SNCA
excitatory synapse assembly (GO:1904861),3/8,0.003734224,0.054444986,8.75e+9,4.89e+9,SHANK3;SHANK2;SHANK1
cellular response to oxidative stress (GO:0034599),12/115,0.003831926,0.05571031,2.44e+9,1.36e+8,PRDX3;PRDX2;GPX1;PRDX1;TXNRD1;LONP1;CYCS;TXN;SOD2;PRDX6;SNCA;MAPK3
"regulation of mRNA splicing, via spliceosome (GO:0048024)",8/60,0.003911565,0.056706575,3.11e+9,1.73e+9,SON;SNW1;FMR1;SRSF3;SRSF4;RNPS1;SRSF6;PRDX6
regulation of filopodium assembly (GO:0051489),6/36,0.003939703,0.056952704,3.89e+9,2.15e+9,CDC42;NRP1;DMTN;FMR1;FSCN1;AGRN
positive regulation of macromolecule metabolic process (GO:0010604),22/276,0.003992867,0.05755819,1.86e+9,1.03e+9,ATAD1;NSF;RPL5;MTPN;NTRK2;MAP2K1;GSK3A;FMR1;EPHX2;PDCD5;AKR1B1;SCRIB;CTCF;MTOR;RIMS2;RIMS1;HGS;DDRGK1;EZR;VAMP3;SNCA;MAPK3
RNA processing (GO:0006396),17/193,0.003997628,0.057464498,2.06e+9,1.14e+8,DHX9;HNRNPR;LSM5;PRPF8;PPP1R9B;SON;SNRPD2;DDX39B;HNRNPUL1;PABPN1;PPP2R1A;SNRPD1;HNRNPA2B1;RNPS1;SRSF4;SNRPD3;SRSF5
peptidyl-threonine dephosphorylation (GO:0035970),4/16,0.004031639,0.057790601,5.83e+9,3.22e+9,PPM1A;PPP5C;PPM1E;PPP1CA
MAPK cascade (GO:0000165),22/278,0.004348758,0.062161662,1.85e+9,1.00e+8,YWHAE;CAMK2B;SPTBN4;MAP2K1;PSMD12;MINK1;CAMK2A;FGF1;GRIN2B;RBX1;PSMB7;PPP5C;PSMD7;PSMC6;PABPN1;PSMD5;PSMB1;LAMTOR2;CALM1;MARK3;SHANK3;MAPK3
sodium ion homeostasis (GO:0055078),5/26,0.004434095,0.06320443,4.49e+9,2.43e+9,ATP1A3;ATP1A2;ATP1B2;ATP1B1;SLC9A1
positive regulation of axonogenesis (GO:0050772),6/37,0.004534967,0.064462223,3.78e+8,2.04e+9,NTRK2;TUBB2B;TWF2;PLXNB1;PLXNA4;RHOA
positive regulation of stress fiber assembly (GO:0051496),6/37,0.004534967,0.064283162,3.78e+8,2.04e+9,CDC42;NRP1;RAC1;PPM1E;RHOA;PFN2
protein import into nucleus (GO:0006606),11/103,0.004621688,0.065330957,2.49e+9,1.34e+9,PDIA3;NCKIPSD;OPRD1;RANBP1;NUP107;RANBP3;CTNNB1;NUTF2;KPNA3;KPNB1;RAN
glutathione metabolic process (GO:0006749),7/49,0.004624003,0.065183119,3.33e+9,1.79e+9,EEF1G;GPX1;ALDH5A1;GSS;GDAP1L1;GDAP1;CNDP2
cytosolic transport (GO:0016482),12/118,0.004721439,0.066373285,2.37e+9,1.27e+9,STX16;STX8;VPS53;CLTC;UBE2O;VPS26A;AP2A1;VPS26B;SNX5;TBC1D10B;VTI1B;VAMP3
endocytosis (GO:0006897),21/263,0.004749183,0.066579895,1.86e+9,9.97e+9,HSP90AA1;AHSG;WIPF3;CLTC;RHOG;AP2A1;SYP;CORO1A;HSP90B1;CORO1C;CDC42;CTTN;MYO6;ALB;AP1S1;HYOU1;APOE;RAC1;SNX5;ATP9A;MAPK3
negative regulation of antigen receptor-mediated signaling pathway (GO:0050858),4/17,0.005095453,0.071238626,5.49e+9,2.90e+9,PRNP;THY1;PHPT1;EZR
positive regulation of cellular protein catabolic process (GO:1903364),4/17,0.005095453,0.071043985,5.49e+9,2.90e+9,HSP90AA1;ATPIF1;APOE;EZR
regulation of receptor recycling (GO:0001919),4/17,0.005095453,0.070850405,5.49e+9,2.90e+9,NSF;SCRIB;VAMP3;SNCA
chaperone-mediated protein complex assembly (GO:0051131),4/17,0.005095453,0.070657877,5.49e+9,2.90e+9,HSP90AA1;HSP90AB1;HSPA4;LONP1
membrane depolarization during cardiac muscle cell action potential (GO:0086012),4/17,0.005095453,0.070466392,5.49e+9,2.90e+9,HCN4;CACNA2D1;ATP1A2;HCN2
potassium ion import (GO:0010107),6/38,0.005193902,0.07163373,3.68e+9,1.94e+7,KCNJ10;SLC12A5;ATP1A3;ATP1A2;ATP1B2;ATP1B1
purine ribonucleoside triphosphate biosynthetic process (GO:0009206),5/27,0.005253043,0.072254121,4.32e+9,2.27e+9,ATP5B;ATP5A1;ATP5O;ATP5F1;ATP5J2
regulation of neurotransmitter secretion (GO:0046928),5/27,0.005253043,0.07205989,4.32e+9,2.27e+9,RIMS2;RIMS1;FMR1;CAMK2A;CPLX1
cellular response to topologically incorrect protein (GO:0035967),5/27,0.005253043,0.0718667,4.32e+9,2.27e+9,HSPA8;HSPA5;HSPA4;HYOU1;HSPA2
nucleoside phosphate biosynthetic process (GO:1901293),3/9,0.005423909,0.0740059,7.78e+8,4.06e+9,CMPK1;CMPK2;SUCLG1
cellular response to oxygen levels (GO:0071453),3/9,0.005423909,0.073808551,7.78e+8,4.06e+9,ATP6V1A;ATP6V1G1;ATP6V0D1
nucleoside triphosphate biosynthetic process (GO:0009142),3/9,0.005423909,0.073612252,7.78e+8,4.06e+9,CMPK1;CMPK2;SUCLG1
mitochondrial protein processing (GO:0034982),3/9,0.005423909,0.073416994,7.78e+8,4.06e+9,AFG3L2;STOML2;UQCRC2
postsynaptic density organization (GO:0097106),3/9,0.005423909,0.073222769,7.78e+8,4.06e+9,SHANK3;SHANK2;SHANK1
establishment of epithelial cell apical/basal polarity (GO:0045198),3/9,0.005423909,0.073029569,7.78e+8,4.06e+9,CDC42;CAMSAP3;RHOA
acidic amino acid transport (GO:0015800),3/9,0.005423909,0.072837386,7.78e+8,4.06e+9,PRAF2;SLC1A3;SLC25A22
regulation of protein catabolic process (GO:0042176),10/91,0.005537209,0.074163717,2.56e+9,1.33e+9,NSF;EEF1A1;GSK3A;NDUFA13;VCP;APC;HGS;EEF1A2;AGAP2;FMN2
response to endoplasmic reticulum stress (GO:0034976),11/106,0.005741472,0.076698253,2.42e+9,1.25e+9,PDIA3;VCP;HSPA5;AIFM1;DDRGK1;UBA5;UFC1;UBQLN1;ATP2A2;HYOU1;HSP90B1
negative regulation of neuron projection development (GO:0010977),7/51,0.005789706,0.077140659,3.20e+9,1.65e+9,LINGO1;PTPRS;GDI1;CRMP1;THY1;APOE;RHOA
coenzyme metabolic process (GO:0006732),7/51,0.005789706,0.076939771,3.20e+9,1.65e+9,THTPA;ACLY;ACOT7;FASN;DBT;ACSL6;DBI
regulation of mitotic cell cycle phase transition (GO:1901990),16/184,0.005807812,0.076979913,2.03e+9,1.04e+9,YWHAE;DYNC1I2;DYNC1H1;PSMD12;HSP90AA1;DCTN2;TUBB4A;TUBA4A;PPP1R9B;PSMB7;ACTR1A;PSMD7;PSMC6;PPP2R1A;PSMD5;PSMB1
cellular response to decreased oxygen levels (GO:0036294),8/64,0.005827642,0.077042636,2.92e+9,1.50e+9,OPRD1;NPEPPS;HP1BP3;PGK1;UBQLN1;HYOU1;FMN2;MTOR
positive regulation of cellular metabolic process (GO:0031325),10/92,0.00598056,0.078859946,2.54e+8,1.30e+9,NSF;ATAD1;ACLY;FMR1;RAB1B;FASN;SCRIB;APOE;VAMP3;SNCA
antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590),9/78,0.006044852,0.079502265,2.69e+9,1.38e+9,PDIA3;PSMB7;PSMD12;PSMD7;PSMC6;PSMD5;PSMB1;LNPEP;VAMP3
viral life cycle (GO:0019058),11/107,0.006158768,0.080792265,2.40e+9,1.22e+9,VCP;NUP107;HSP90AB1;VTA1;RAB1B;CHMP4B;APOE;KPNA3;PPIA;KPNB1;RAN
cellular response to ketone (GO:1901655),5/28,0.006173408,0.080776668,4.17e+9,2.12e+9,LARP1;GNG2;GNB1;DCPS;PCK2
cellular response to alcohol (GO:0097306),5/28,0.006173408,0.080570078,4.17e+9,2.12e+9,GNG2;LARP1;GNB1;CTNNA1;CTNNB1
regulation of mRNA processing (GO:0050684),5/28,0.006173408,0.080364542,4.17e+9,2.12e+9,AHCYL1;SON;PABPN1;DHX9;SRSF3
dopamine receptor signaling pathway (GO:0007212),5/28,0.006173408,0.080160053,4.17e+9,2.12e+9,GNAO1;GSK3A;GNG2;GNB1;GNB5
regulation of adherens junction organization (GO:1903391),4/18,0.006332088,0.082011789,5.19e+9,2.63e+9,CAMSAP3;RHOA;SLC9A1;CORO1C
organelle fusion (GO:0048284),4/18,0.006332088,0.081804164,5.19e+9,2.63e+9,AFG3L2;OPA1;MFF;GDAP1
regulation of spindle organization (GO:0090224),4/18,0.006332088,0.081597588,5.19e+9,2.63e+9,DYNC1H1;NUMA1;CLTC;MAP9
establishment or maintenance of apical/basal cell polarity (GO:0035088),4/18,0.006332088,0.081392053,5.19e+9,2.63e+9,CLIC4;DLG3;FSCN1;SCRIB
positive regulation of actin cytoskeleton reorganization (GO:2000251),4/18,0.006332088,0.08118755,5.19e+9,2.63e+9,CDC42;NRP1;HAX1;BAIAP2
glyceraldehyde-3-phosphate metabolic process (GO:0019682),4/18,0.006332088,0.080984073,5.19e+9,2.63e+9,TPI1;TALDO1;PGLS;PGD
"positive regulation of synaptic transmission, glutamatergic (GO:0051968)",4/18,0.006332088,0.080781612,5.19e+9,2.63e+9,PTK2B;SHANK3;SHANK2;SHANK1
ion transmembrane transport (GO:0034220),18/219,0.006395328,0.081384939,1.92e+9,9.69e+9,ATP6V1A;ATP6V1G1;ATP6V1G2;ATP2A2;ATP1A3;ATP1A2;ATP1B2;ATP2B1;ATP1B1;GJA1;ASPH;ANXA6;ATP6V1B2;ATP6V0D1;ATP6V0C;ATP6V1C1;ATP6V0A1;ATP6V1F
fatty acid catabolic process (GO:0009062),8/65,0.006402347,0.081271584,2.87e+9,1.45e+9,HADHB;HADHA;ECHS1;AUH;ABHD16A;ECI1;PCCB;HSD17B4
plasma membrane bounded cell projection morphogenesis (GO:0120039),7/52,0.006448765,0.081657682,3.14e+9,1.58e+9,NCKAP1;CTTN;MINK1;RHOG;PLXNB1;RAC1;DCLK1
regulation of cellular localization (GO:0060341),6/40,0.006718057,0.084857046,3.50e+9,1.75e+9,RIMS1;DYNC1H1;NUMA1;FMR1;CAMK2A;CPLX1
response to cAMP (GO:0051591),6/40,0.006718057,0.084647522,3.50e+9,1.75e+9,HCN4;RAP1B;DMTN;VGF;EZR;HCN2
regulation of protein dephosphorylation (GO:0035304),6/40,0.006718057,0.084439031,3.50e+9,1.75e+9,PPP1R2;PPP1R14B;PPP1R8;SYMPK;CALM1;HSP90B1
axon development (GO:0061564),10/94,0.006949844,0.087137729,2.48e+9,1.23e+9,RAB10;AFG3L2;SPTBN4;BRSK1;LINGO1;MAP1A;PLP1;BAIAP2;NEFH;CAMSAP2
platelet degranulation (GO:0002576),12/124,0.006992126,0.087452986,2.26e+9,1.12e+7,ISLR;WDR1;AHSG;STXBP1;PCDH7;ALB;HABP4;PHACTR2;TLN1;CALM1;TUBA4A;VTI1B
coenzyme biosynthetic process (GO:0009108),5/29,0.007201361,0.089849747,4.02e+9,1.99e+9,MOCS3;ACOT7;SPR;RFK;ATPIF1
inorganic cation transmembrane transport (GO:0098662),13/140,0.007202794,0.089648429,2.17e+9,1.07e+8,HCN4;SLC30A3;ATP2A2;ATP5O;ATP5J2;SLC9A1;ATP5B;ATP6V1B2;ATP6V0D1;ATP6V0C;ATP6V1C1;HCN2;ATP6V1F
protein complex assembly (GO:0006461),16/189,0.007465733,0.092694977,1.98e+9,9.68e+8,NSF;TRAPPC3;STOML2;SEC23A;AHNAK;ST13;RAB1B;AKR1B1;SLC9A1;AFG3L2;GRHPR;PFKL;OPA1;APC;CTNNB1;PFKM
cellular response to oxygen-containing compound (GO:1901701),21/274,0.007498948,0.092881381,1.79e+9,8.75e+9,HCN4;NDUFA13;DMTN;TWF2;PDXP;RHOA;MTOR;HSP90B1;PRDX3;RAP1B;SNW1;GNG2;PABPN1;LARS;RUVBL2;GNB1;PTK2B;LAMTOR2;EZR;HCN2;MAPK3
establishment of spindle localization (GO:0051293),3/10,0.007503558,0.092713454,7.00e+9,3.43e+9,DYNC1H1;MAP4;KPNB1
regulation of platelet-derived growth factor receptor signaling pathway (GO:0010640),3/10,0.007503558,0.092489508,7.00e+9,3.43e+9,NDRG4;HGS;SNCA
glutamine metabolic process (GO:0006541),3/10,0.007503558,0.092266642,7.00e+9,3.43e+9,ALDH5A1;GLUL;GLS
actin filament capping (GO:0051693),3/10,0.007503558,0.092044847,7.00e+9,3.43e+9,TWF2;TWF1;ADD2
maintenance of apical/basal cell polarity (GO:0035090),3/10,0.007503558,0.091824116,7.00e+9,3.43e+9,WDR1;LIN7C;LIN7B
dicarboxylic acid biosynthetic process (GO:0043650),3/10,0.007503558,0.091604441,7.00e+9,3.43e+9,GOT1;MTHFD1;GLS
maintenance of epithelial cell apical/basal polarity (GO:0045199),3/10,0.007503558,0.091385815,7.00e+9,3.43e+9,WDR1;LIN7C;LIN7B
"energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)",3/10,0.007503558,0.09116823,7.00e+9,3.43e+9,NDUFS7;ATP1A3;ATP1A2
aspartate family amino acid metabolic process (GO:0009066),3/10,0.007503558,0.090951678,7.00e+9,3.43e+9,GOT1;MTHFD1;GOT2
regulation of protein localization to plasma membrane (GO:1903076),8/67,0.007679401,0.092862524,2.79e+9,1.36e+9,STX8;PRKCE;CLTC;RHOG;AKR1B1;AP2M1;PLS1;VTI1B
positive regulation of binding (GO:0051099),9/81,0.00772377,0.093178241,2.59e+9,1.26e+9,GPSM1;DHX9;STMN1;EDF1;HMGB1;TXN;APOE;RAN;ADD2
Rac protein signal transduction (GO:0016601),4/19,0.007752703,0.093306702,4.91e+9,2.39e+9,NCKAP1;RHOG;CDH13;RAC1
excitatory postsynaptic potential (GO:0060079),4/19,0.007752703,0.093087157,4.91e+9,2.39e+9,MPP2;GSK3A;GRIN2B;RAB3GAP1
ribosomal small subunit assembly (GO:0000028),4/19,0.007752703,0.092868642,4.91e+9,2.39e+9,RPS14;RPS19;RPS5;RPSA
aspartate family amino acid catabolic process (GO:0009068),4/19,0.007752703,0.092651151,4.91e+9,2.39e+9,GOT1;GOT2;DLST;ASPA
protein homooligomerization (GO:0051260),16/190,0.007838906,0.093462475,1.97e+9,9.53e+9,PRNP;MPP2;SYT1;ATPIF1;MIF;MFF;SOD2;HSD17B10;CLYBL;GLS;LETM1;ALDH5A1;APC;LONP1;ANXA6;CHMP4B
G2/M transition of mitotic cell cycle (GO:0000086),12/126,0.007915214,0.0941523,2.22e+9,1.08e+9,YWHAE;DYNC1I2;DYNC1H1;ACTR1A;HSP90AA1;PPP1R12A;DCTN2;PPP2R1A;PPME1;PLCB1;TUBB4A;TUBA4A
cellular metal ion homeostasis (GO:0006875),10/96,0.008036502,0.095372724,2.43e+9,1.17e+9,LETM1;STOML2;EPHX2;ATP2A2;ATP1A3;ATP1A2;ATP1B2;ATP2B1;ATP1B1;SLC9A1
axon guidance (GO:0007411),14/158,0.008103622,0.095946133,2.07e+9,9.96e+9,CYFIP2;SPTBN4;NRP1;PTPN11;MLF2;RPS6KA5;TUBB3;GPC1;TNR;PLXNB1;EZR;SHANK3;PLXNA4;MAPK3
cellular response to cAMP (GO:0071320),5/30,0.008342917,0.098550702,3.89e+9,1.86e+9,HCN4;RAP1B;DMTN;EZR;HCN2
peptidyl-threonine phosphorylation (GO:0018107),8/68,0.008385458,0.098824459,2.75e+9,1.31e+9,CAMK2B;GSK3A;MAP2K1;WNK1;CSNK2B;CAMK2A;CAMKK1;DCLK1
cell cycle G2/M phase transition (GO:0044839),12/127,0.008411185,0.098899259,2.21e+9,1.05e+9,YWHAE;DYNC1I2;DYNC1H1;ACTR1A;HSP90AA1;PPP1R12A;DCTN2;PPP2R1A;PPME1;PLCB1;TUBB4A;TUBA4A
positive regulation of cellular biosynthetic process (GO:0031328),14/159,0.008547287,0.100268523,2.05e+9,9.79e+9,RPL5;HSP90AA1;HSP90AB1;DHX9;POLDIP3;FMR1;CIRBP;LARP4;EEF2;ELAVL1;MTOR;VIM;EIF3D;SNCA
mRNA metabolic process (GO:0016071),10/97,0.008626607,0.100966913,2.41e+9,1.14e+9,SON;CPSF1;AGO3;HNRNPA2B1;HNRNPR;SRSF4;SNRPD3;SRSF5;LSM5;PRPF8
regulation of RNA splicing (GO:0043484),7/55,0.008761498,0.102311035,2.97e+9,1.41e+9,SON;AHNAK;POLR2A;HABP4;SRSF3;RPS13;PTBP2
positive regulation of cysteine-type endopeptidase activity (GO:2001056),7/55,0.008761498,0.102077448,2.97e+9,1.41e+9,CYFIP2;NDUFA13;ASPH;PDCD5;CYCS;HMGB1;GRIN2B
negative regulation of cell cycle G2/M phase transition (GO:1902750),8/69,0.009139012,0.106233204,2.71e+8,1.27e+9,PSMB7;PSMD12;PSMD7;PSMC6;H2AFY;PSMD5;PSMB1;RBX1
positive regulation of neuron differentiation (GO:0045666),10/98,0.009249382,0.107271808,2.38e+9,1.12e+9,CAMK2B;NTRK2;NDRG4;KIDINS220;TWF2;NPTN;TWF1;PTK2B;APOE;RHOA
vacuolar acidification (GO:0007035),4/20,0.009367666,0.108397273,4.67e+9,2.18e+9,ATP6V0D1;ATP6V0C;CLN6;ATP6V0A1
negative regulation of actin filament bundle assembly (GO:0032232),4/20,0.009367666,0.10815203,4.67e+9,2.18e+9,STMN1;SHANK3;SHANK1;CLASP2
regulation of calcium ion transmembrane transport (GO:1903169),4/20,0.009367666,0.107907895,4.67e+9,2.18e+9,PRNP;CACNA2D1;PTK2B;ATP1A2
axon extension (GO:0048675),4/20,0.009367666,0.107664859,4.67e+9,2.18e+9,NRP1;PPP3CB;USP9X;PLXNB1
Arp2/3 complex-mediated actin nucleation (GO:0034314),4/20,0.009367666,0.107422916,4.67e+9,2.18e+9,ACTR3;ACTR2;ARPC1A;ARPC4
cytoskeleton-dependent cytokinesis (GO:0061640),8/70,0.009941921,0.113752522,2.67e+9,1.23e+9,SON;APC;STMN1;RAB35;CHMP4B;RHOA;SEPT3;RHOB
brain morphogenesis (GO:0048854),3/11,0.009992065,0.114070491,6.36e+9,2.93e+9,SHANK3;SHANK2;SHANK1
regulation of mitotic centrosome separation (GO:0046602),3/11,0.009992065,0.113815869,6.36e+9,2.93e+9,RANBP1;RANBP3;MAP9
relaxation of cardiac muscle (GO:0055119),3/11,0.009992065,0.113562382,6.36e+9,2.93e+9,CHGA;ATP1A2;ATP1B1
stress granule assembly (GO:0034063),3/11,0.009992065,0.113310021,6.36e+9,2.93e+9,DYNC1H1;ATXN2;CIRBP
positive regulation of actin filament depolymerization (GO:0030836),3/11,0.009992065,0.113058779,6.36e+9,2.93e+9,WDR1;CFL2;PDXP
regulation of synaptic vesicle cycle (GO:0098693),3/11,0.009992065,0.112808649,6.36e+9,2.93e+9,RIMS2;RIMS1;SNCA
cellular response to increased oxygen levels (GO:0036295),3/11,0.009992065,0.112559623,6.36e+9,2.93e+9,ATP6V1A;ATP6V1G1;ATP6V0D1
positive regulation of sodium ion transmembrane transporter activity (GO:2000651),3/11,0.009992065,0.112311695,6.36e+9,2.93e+9,DMD;ATP1B1;SLC9A1
oxidative phosphorylation (GO:0006119),3/11,0.009992065,0.112064856,6.36e+9,2.93e+9,UQCRB;UQCRC1;UQCRC2
hepatocyte growth factor receptor signaling pathway (GO:0048012),3/11,0.009992065,0.111819099,6.36e+9,2.93e+9,NRP1;STMN1;RAC1
positive regulation of actin filament bundle assembly (GO:0032233),6/44,0.010697128,0.119447366,3.18e+9,1.44e+9,CDC42;NRP1;RAC1;PPM1E;RHOA;PFN2
ribosomal small subunit biogenesis (GO:0042274),6/44,0.010697128,0.119186564,3.18e+9,1.44e+9,RPS14;RPS16;RPS19;RPS5;RPS6;RPSA
response to insulin (GO:0032868),8/71,0.01079604,0.120026562,2.63e+9,1.19e+9,RAB10;GSK3A;PKM;GOT1;DENND4C;MYO5A;VAMP2;PCK2
regulation of glutamate receptor signaling pathway (GO:1900449),5/32,0.010989925,0.121916499,3.65e+9,1.64e+9,MINK1;PTK2B;SHANK3;SHANK2;SHANK1
microtubule bundle formation (GO:0001578),5/32,0.010989925,0.121652038,3.65e+9,1.64e+9,CLIP1;TPPP3;NUMA1;NAV1;MAPRE2
oxoacid metabolic process (GO:0043436),5/32,0.010989925,0.121388722,3.65e+9,1.64e+9,PODXL2;PPA1;BPNT1;MIF;SULT4A1
regulation of peptidyl-serine phosphorylation (GO:0033135),9/86,0.011282741,0.124353843,2.44e+8,1.10e+9,OPRD1;SPTBN4;HAX1;DMTN;DMD;MIF;TXN;PFN2;SNCA
phospholipid transport (GO:0015914),7/58,0.011631075,0.127916755,2.82e+9,1.25e+9,TMEM30A;SCP2;PITPNM1;PITPNA;STARD10;APOE;ATP9A
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0031146),8/72,0.011703212,0.12843331,2.59e+9,1.15e+9,PSMB7;PSMD12;PSMD7;PSMC6;PSMD5;FBXO2;PSMB1;RBX1
central nervous system development (GO:0007417),17/217,0.01238731,0.135649016,1.83e+7,8.03e+9,NCKAP1;NDRG4;FMR1;SMG9;PTPN11;GRIN2B;DCLK1;ALDH5A1;H2AFY2;PITPNM1;CDH2;RAB18;PHGDH;CIC;PAFAH1B2;RAB3GAP1;SH3GL2
cellular response to interleukin-1 (GO:0071347),13/150,0.012482647,0.136400312,2.02e+9,8.87e+9,PSMD12;USP10;RBX1;PSMB7;PSMD7;RPS6KA5;PSMC6;PSMD5;TOLLIP;PSMB1;UBE2V1;PLCB1;MAPK3
positive regulation of cell-matrix adhesion (GO:0001954),5/33,0.012506367,0.136367501,3.54e+9,1.55e+9,NRP1;PTK2B;CDH13;THY1;RAC1
mRNA stabilization (GO:0048255),5/33,0.012506367,0.136076739,3.54e+9,1.55e+9,LARP1;DHX9;CIRBP;YBX1;ELAVL1
regulation of neurotransmitter receptor activity (GO:0099601),5/33,0.012506367,0.135787214,3.54e+9,1.55e+9,MINK1;PTK2B;SHANK3;SHANK2;SHANK1
mitotic cytokinesis (GO:0000281),7/59,0.012723054,0.137846586,2.77e+9,1.21e+9,SON;APC;STMN1;RAB35;CHMP4B;SEPT3;RHOB
ribose phosphate metabolic process (GO:0019693),3/12,0.012903633,0.139506862,5.83e+9,2.54e+9,TALDO1;PGLS;PGD
viral RNA genome replication (GO:0039694),3/12,0.012903633,0.139211921,5.83e+9,2.54e+9,CDC42;PCBP1;PI4KA
positive regulation of keratinocyte differentiation (GO:0045618),3/12,0.012903633,0.138918225,5.83e+9,2.54e+9,H2AFY;NUMA1;H2AFY2
eye photoreceptor cell development (GO:0042462),3/12,0.012903633,0.138625766,5.83e+9,2.54e+9,TH;THY1;MAPRE2
regulation of protein localization to cell periphery (GO:1904375),3/12,0.012903633,0.138334535,5.83e+9,2.54e+9,STX8;AKR1B1;VTI1B
spliceosomal tri-snRNP complex assembly (GO:0000244),3/12,0.012903633,0.138044526,5.83e+9,2.54e+9,SART3;PRPF19;PRPF8
positive regulation of protein depolymerization (GO:1901881),3/12,0.012903633,0.13775573,5.83e+9,2.54e+9,WDR1;CFL2;PDXP
regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter (GO:1901836),3/12,0.012903633,0.137468139,5.83e+9,2.54e+9,H2AFY;H2AFY2;MTOR
pentose-phosphate shunt (GO:0006098),3/12,0.012903633,0.137181747,5.83e+9,2.54e+9,TALDO1;PGLS;PGD
regulation of actomyosin structure organization (GO:0110020),3/12,0.012903633,0.136896546,5.83e+9,2.54e+9,CDC42;RAC1;SLC9A1
pre-mRNA cleavage required for polyadenylation (GO:0098789),3/12,0.012903633,0.136612529,5.83e+9,2.54e+9,CPSF7;CPSF1;CSTF2
cellular response to nerve growth factor stimulus (GO:1990090),4/22,0.013217896,0.139649945,4.24e+9,1.84e+9,NTRK2;KIDINS220;RAB35;SH3GL2
negative regulation of actin filament polymerization (GO:0030837),4/22,0.013217896,0.139361412,4.24e+9,1.84e+9,TWF2;TWF1;KANK3;PFN2
viral genome replication (GO:0019079),4/22,0.013217896,0.139074069,4.24e+9,1.84e+9,CDC42;VCP;PCBP1;PI4KA
positive regulation of RNA splicing (GO:0033120),4/22,0.013217896,0.138787909,4.24e+9,1.84e+9,SNW1;POLR2A;HABP4;PRDX6
regulation of cellular response to stress (GO:0080135),10/104,0.013735127,0.143922695,2.24e+9,9.62e+9,YWHAE;CAMK2B;HSPA8;HSP90AA1;NUP107;HSP90AB1;AKT1S1;CAMK2A;MTOR;MAPK3
protein stabilization (GO:0050821),13/152,0.013827544,0.144594177,2.00e+9,8.54e+9,CCT3;RPL5;HSP90AA1;HSP90AB1;ATP1B2;ATP1B1;TCP1;AAK1;CCT8;PPIB;CCT7;CCT5;PFN2
positive regulation of muscle cell differentiation (GO:0051149),5/34,0.014158341,0.147750542,3.43e+8,1.46e+8,CDC42;CDH2;CTNNA1;CTNNB1;PLCB1
regulation of axon extension (GO:0030516),5/34,0.014158341,0.14744901,3.43e+8,1.46e+8,PTPRS;CTTN;TWF2;APOE;PLXNA4
positive regulation of organelle assembly (GO:1902117),6/47,0.014610479,0.151847808,2.98e+9,1.26e+9,DYNC1H1;NUMA1;CROCC;FSCN1;PIP4K2A;RAB3GAP1
negative regulation of cellular amide metabolic process (GO:0034249),8/75,0.014761278,0.153103259,2.49e+9,1.05e+9,PRNP;LARP1;FMR1;CAPRIN1;APOE;EPRS;GIGYF2;SNCA
"antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:0002479)",8/75,0.014761278,0.152792704,2.49e+9,1.05e+9,PDIA3;PSMB7;PSMD12;PSMD7;PSMC6;PSMD5;PSMB1;VAMP3
purine ribonucleotide biosynthetic process (GO:0009152),8/75,0.014761278,0.152483407,2.49e+9,1.05e+9,ATP5B;ACOT7;ATP5A1;GMPS;ATP5F1;ADCY8;ATP5O;ATP5J2
protein tetramerization (GO:0051262),9/90,0.014916616,0.153776747,2.33e+9,9.81e+9,CPSF7;ALDH5A1;RPS19;ATPIF1;RCC1;SOD2;HSD17B10;GRIN2B;GLS
regulation of proteolysis involved in cellular protein catabolic process (GO:1903050),4/23,0.015469601,0.159155994,4.06e+9,1.69e+9,USP14;GPX1;ATPIF1;PTK2B
regulation of dendritic spine morphogenesis (GO:0061001),4/23,0.015469601,0.158835761,4.06e+9,1.69e+9,CAMK2B;SIPA1L1;CAPRIN1;SHANK3
positive regulation of ion transmembrane transporter activity (GO:0032414),4/23,0.015469601,0.158516814,4.06e+9,1.69e+9,WNK1;DMD;ATP1B2;ATP1B1
regulation of microtubule cytoskeleton organization (GO:0070507),4/23,0.015469601,0.158199145,4.06e+9,1.69e+9,CAMSAP3;PHLDB1;STMN1;CLASP2
regulation of ion homeostasis (GO:2000021),4/23,0.015469601,0.157882746,4.06e+9,1.69e+9,HCN4;SLC30A3;WNK1;AP3D1
regulation of mitotic spindle organization (GO:0060236),5/35,0.015950686,0.162467768,3.33e+9,1.38e+9,DYNC1H1;NUMA1;CLTC;CHMP4B;MAP9
positive regulation of telomerase activity (GO:0051973),5/35,0.015950686,0.162144127,3.33e+9,1.38e+9,HSP90AA1;HSP90AB1;TCP1;HNRNPA2B1;MAPK3
apical junction assembly (GO:0043297),5/35,0.015950686,0.161821773,3.33e+9,1.38e+9,WDR1;APC;CTNNA1;TBCD;RHOA
regulation of acyl-CoA biosynthetic process (GO:0050812),3/13,0.016248238,0.164513412,5.39e+8,2.22e+9,PDHA1;PDHB;DLAT
mitochondrial genome maintenance (GO:0000002),3/13,0.016248238,0.164187642,5.39e+8,2.22e+9,OPA1;LONP1;SLC25A4
regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510),3/13,0.016248238,0.163863161,5.39e+8,2.22e+9,PDHA1;PDHB;DLAT
cardiolipin metabolic process (GO:0032048),3/13,0.016248238,0.163539959,5.39e+8,2.22e+9,HADHB;HADHA;PDXP
membrane repolarization (GO:0086009),3/13,0.016248238,0.16321803,5.39e+8,2.22e+9,ATP1A2;ATP1B2;ATP1B1
semaphorin-plexin signaling pathway involved in neuron projection guidance (GO:1902285),3/13,0.016248238,0.162897366,5.39e+8,2.22e+9,NRP1;PLXNB1;PLXNA4
regulation of synaptic vesicle transport (GO:1902803),3/13,0.016248238,0.16257796,5.39e+8,2.22e+9,RIMS2;RIMS1;SNCA
"negative regulation of mRNA splicing, via spliceosome (GO:0048025)",3/13,0.016248238,0.162259803,5.39e+8,2.22e+9,RNPS1;SRSF4;SRSF6
mRNA cleavage involved in mRNA processing (GO:0098787),3/13,0.016248238,0.16194289,5.39e+8,2.22e+9,CPSF7;CPSF1;CSTF2
regulation of axon guidance (GO:1902667),3/13,0.016248238,0.161627211,5.39e+8,2.22e+9,NRP1;TUBB2B;PLXNA4
negative regulation of G2/M transition of mitotic cell cycle (GO:0010972),7/62,0.0164393,0.163209623,2.63e+9,1.08e+9,PSMB7;PSMD12;PSMD7;PSMC6;PSMD5;PSMB1;RBX1
regulation of primary metabolic process (GO:0080090),12/139,0.016447895,0.162977879,2.01e+9,8.28e+9,TIAM2;PSMB7;PSMD12;PSMD7;PSMC6;H2AFY;PSMD5;TXNRD1;CARM1;PSMB1;EDF1;APOE
regulation of small GTPase mediated signal transduction (GO:0051056),12/140,0.017314624,0.171233579,2.00e+9,8.11e+8,TIAM2;CDC42;ARHGAP32;TRIO;GDI1;ARHGDIB;GDI2;RHOG;RAC1;RHOA;CD2AP;RHOB
axonal transport (GO:0098930),5/36,0.017887945,0.176561284,3.24e+9,1.30e+9,AP3M2;KIF3B;OPA1;FMR1;AP3D1
regulation of nitric-oxide synthase activity (GO:0050999),5/36,0.017887945,0.176220432,3.24e+9,1.30e+9,HSP90AA1;SPR;APOE;CALM1;CYGB
negative regulation of protein localization to membrane (GO:1905476),4/24,0.017948495,0.176476241,3.89e+9,1.56e+8,DMTN;GDI1;CLTC;AP2M1
positive regulation of purine nucleotide biosynthetic process (GO:1900373),4/24,0.017948495,0.176136864,3.89e+9,1.56e+8,VCP;ENO1;APOE;CALM1
receptor clustering (GO:0043113),4/24,0.017948495,0.175798789,3.89e+9,1.56e+8,DLG3;SCRIB;THY1;AGRN
cellular modified amino acid biosynthetic process (GO:0042398),4/24,0.017948495,0.17546201,3.89e+9,1.56e+8,GAMT;GSS;ATPIF1;CNDP2
regulation of AMPA receptor activity (GO:2000311),4/24,0.017948495,0.175126518,3.89e+9,1.56e+8,MINK1;SHANK3;SHANK2;SHANK1
actin nucleation (GO:0045010),4/24,0.017948495,0.174792308,3.89e+9,1.56e+8,ACTR3;ACTR2;ARPC1A;ARPC4
regulation of transcription from RNA polymerase II promoter in response to hypoxia (GO:0061418),8/78,0.018361586,0.17847462,2.39e+8,9.57e+9,PSMB7;PSMD12;PSMD7;PSMC6;PSMD5;PSMB1;HIGD1A;RBX1
fatty acid oxidation (GO:0019395),6/50,0.019421686,0.188419895,2.80e+9,1.10e+9,HADHB;HADHA;ECHS1;AUH;ECI1;HSD17B4
regulation of fibroblast migration (GO:0010762),3/14,0.020032065,0.193972729,5.00e+9,1.96e+9,DMTN;PRKCE;CORO1C
negative regulation of focal adhesion assembly (GO:0051895),3/14,0.020032065,0.193605357,5.00e+9,1.96e+9,DMTN;CORO1C;CLASP2
response to ethanol (GO:0045471),3/14,0.020032065,0.193239373,5.00e+9,1.96e+9,TH;GOT2;GRIN2B
nucleoside triphosphate metabolic process (GO:0009141),3/14,0.020032065,0.19287477,5.00e+9,1.96e+9,CMPK1;CMPK2;SUCLG1
regulation of protein modification by small protein conjugation or removal (GO:1903320),3/14,0.020032065,0.192511541,5.00e+9,1.96e+9,HSP90AA1;HSP90AB1;UBQLN1
establishment of protein localization to chromosome (GO:0070199),3/14,0.020032065,0.192149677,5.00e+9,1.96e+9,H2AFY;H2AFY2;RUVBL2
lipid particle organization (GO:0034389),3/14,0.020032065,0.191789171,5.00e+9,1.96e+9,RAB18;PPIA;RAB3GAP1
positive regulation of protein localization to membrane (GO:1905477),9/95,0.020588776,0.196750045,2.21e+9,8.58e+9,YWHAE;PRNP;YWHAQ;PRKCE;PDCD5;RHOG;MFF;YWHAZ;PLS1
organophosphate ester transport (GO:0015748),4/25,0.020660544,0.197066835,3.73e+9,1.45e+9,SCP2;PITPNM1;PITPNA;STARD10
"protein import into nucleus, translocation (GO:0000060)",4/25,0.020660544,0.196699173,3.73e+9,1.45e+9,OPRD1;NUTF2;KPNB1;RAN
regulation of potassium ion transmembrane transporter activity (GO:1901016),4/25,0.020660544,0.19633288,3.73e+9,1.45e+9,YWHAE;ATP1B2;ATP1B1;VAMP2
L-amino acid transport (GO:0015807),4/25,0.020660544,0.195967949,3.73e+9,1.45e+9,SLC7A5;PRAF2;SLC1A3;SLC25A22
regulation of voltage-gated calcium channel activity (GO:1901385),4/25,0.020660544,0.195604372,3.73e+9,1.45e+9,AHNAK;FMR1;DMD;GNB5
inorganic cation import across plasma membrane (GO:0098659),4/25,0.020660544,0.195242142,3.73e+9,1.45e+9,HCN4;CACNA2D1;HCN2;SLC9A1
negative regulation of cell adhesion (GO:0007162),7/65,0.020864325,0.19680342,2.51e+9,9.73e+9,DMTN;ARHGDIB;TBCD;CDH13;PLXNB1;RHOA;PLXNA4
regulation of cellular amine metabolic process (GO:0033238),6/51,0.021239286,0.199970624,2.75e+9,1.06e+8,PSMB7;PSMD12;PSMD7;PSMC6;PSMD5;PSMB1
regulation of telomere maintenance via telomerase (GO:0032210),6/51,0.021239286,0.199602354,2.75e+9,1.06e+8,CCT3;TCP1;CCT8;CCT7;CCT5;MAPK3
regulation of cellular amino acid metabolic process (GO:0006521),6/51,0.021239286,0.199235438,2.75e+9,1.06e+8,PSMB7;PSMD12;PSMD7;PSMC6;PSMD5;PSMB1
ciliary basal body-plasma membrane docking (GO:0097711),9/96,0.021887289,0.20493731,2.19e+9,8.36e+9,YWHAE;DYNC1I2;DYNC1H1;ACTR1A;HSP90AA1;DCTN2;PPP2R1A;TUBB4A;TUBA4A
regulation of cellular amide metabolic process (GO:0034248),5/38,0.022213817,0.207613754,3.07e+8,1.17e+9,CYFIP2;EEF1A1;MTPN;ATXN2;EEF1A2
negative regulation of cell death (GO:0060548),8/81,0.022550303,0.210373299,2.30e+9,8.74e+9,CHGA;ALB;CHMP4B;CTNNB1;APOE;SRSF6;DCPS;SNCA
positive regulation of protein catabolic process (GO:0045732),8/81,0.022550303,0.209989406,2.30e+9,8.74e+9,NSF;GSK3A;NDUFA13;HSP90AA1;VCP;APC;APOE;EZR
positive regulation of cell-substrate adhesion (GO:0010811),6/52,0.023168488,0.215352992,2.69e+9,1.01e+9,CDC42;NRP1;DMTN;CDH13;PTK2B;RAC1
positive regulation of proteolysis (GO:0045862),6/52,0.023168488,0.214961441,2.69e+9,1.01e+9,CYFIP2;NDUFA13;ASPH;ATPIF1;APOE;CLN6
negative regulation of catalytic activity (GO:0043086),4/26,0.023610813,0.218667838,3.59e+8,1.34e+9,CAND1;PPP1R12A;ATPIF1;PHPT1
regulation of microtubule-based process (GO:0032886),4/26,0.023610813,0.2182717,3.59e+8,1.34e+9,CAMSAP3;PHLDB1;APC;CLASP2
regulation of histone acetylation (GO:0035065),4/26,0.023610813,0.217876996,3.59e+8,1.34e+9,RPS6KA5;RUVBL2;MAPK3;SNCA
regulation of T cell receptor signaling pathway (GO:0050856),4/26,0.023610813,0.217483716,3.59e+8,1.34e+9,PRNP;THY1;PHPT1;EZR
generation of neurons (GO:0048699),11/130,0.024050421,0.221133869,1.97e+9,7.36e+9,BRSK1;NRP1;MTPN;NTRK2;MAP2K1;TUBB2B;MYEF2;TUBB3;USP9X;CTNNB1;NAV1
organonitrogen compound biosynthetic process (GO:1901566),14/181,0.024092826,0.221125342,1.81e+9,6.73e+9,MOCS3;OAT;GOT1;GOT2;STARD10;NMRAL1;GLS;SGPL1;TH;CSNK2B;ESD;DMD;GLUL;ASPA
positive regulation of peptidyl-lysine acetylation (GO:2000758),3/15,0.024257902,0.222240711,4.67e+9,1.74e+9,RPS6KA5;RUVBL2;MAPK3
apoptotic DNA fragmentation (GO:0006309),3/15,0.024257902,0.22184243,4.67e+9,1.74e+9,H1F0;HMGB1;KPNB1
negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642),3/15,0.024257902,0.221445574,4.67e+9,1.74e+9,NDRG4;HGS;SNCA
sodium ion import (GO:0097369),3/15,0.024257902,0.221050136,4.67e+9,1.74e+9,HCN4;HCN2;SLC9A1
sodium ion import across plasma membrane (GO:0098719),3/15,0.024257902,0.220656107,4.67e+9,1.74e+9,HCN4;HCN2;SLC9A1
negative regulation of mRNA processing (GO:0050686),3/15,0.024257902,0.22026348,4.67e+9,1.74e+9,RNPS1;SRSF4;SRSF6
negative regulation of adherens junction organization (GO:1903392),3/15,0.024257902,0.219872249,4.67e+9,1.74e+9,DMTN;CORO1C;CLASP2
chemical synaptic transmission (GO:0007268),20/289,0.024473287,0.221431178,1.62e+9,5.99e+9,OPRD1;NAPB;UNC13A;DTNA;SLC12A5;CNP;SYT1;CPNE6;MINK1;CACNA1B;SLC1A3;SCRIB;GRIN2B;SYN2;CPLX1;TH;DLG3;PLP1;APOE;BSN
negative regulation of neuron death (GO:1901215),8/83,0.025691117,0.219969415,2.25e+9,8.24e+9,CHGA;NTRK2;AGAP2;CHMP4B;PTK2B;APOE;SOD2;SNCA
positive regulation of substrate adhesion-dependent cell spreading (GO:1900026),4/27,0.026803474,0.229109092,3.46e+9,1.25e+9,CDC42;NRP1;DMTN;RAC1
regulation of protein targeting to membrane (GO:0090313),4/27,0.026803474,0.228725966,3.46e+9,1.25e+9,PRNP;DMTN;GDI1;MFF
protein targeting to vacuole (GO:0006623),4/27,0.026803474,0.22834412,3.46e+9,1.25e+9,LARS;HGS;AP3D1;VTI1B
regulation of calcium ion transmembrane transporter activity (GO:1901019),4/27,0.026803474,0.227963546,3.46e+9,1.25e+9,YWHAE;AHNAK;DMD;CALM1
phosphorylation (GO:0016310),25/386,0.026959602,0.228909895,1.51e+9,5.46e+9,CAMK2B;BRSK1;GSK3A;UQCRB;CAMK2A;HK1;PPP3CB;RPS6KA5;PGK1;PTK2B;MAPK3;MAP2K1;PRKCB;PRKCE;MINK1;CDC42BPA;MTOR;DCLK1;WNK1;TOLLIP;UQCRC1;AAK1;SIK3;PI4KA;UQCRC2
neuron migration (GO:0001764),5/40,0.027165907,0.230278444,2.92e+9,1.05e+9,NRP1;NTRK2;TUBB2B;USP9X;NAV1
regulation of cholesterol biosynthetic process (GO:0045540),5/40,0.027165907,0.229896556,2.92e+9,1.05e+9,FASN;APOE;FGF1;KPNB1;RAN
regulation of ATPase activity (GO:0043462),5/40,0.027165907,0.229515933,2.92e+9,1.05e+9,CHTOP;ATPIF1;ATP1B2;ATP1B1;PFN2
protein targeting (GO:0006605),11/133,0.027873302,0.235103236,1.93e+9,6.91e+9,TIMM10B;ATG3;PMM1;TIMM9;AIP;TOMM34;AP3D1;SRP14;MFF;GDAP1;VTI1B
protein localization to cell periphery (GO:1990778),10/117,0.02877241,0.242286485,1.99e+9,7.08e+9,RAB10;SPTBN4;STXBP1;DENND4C;MYO5A;ATP1B1;EZR;LIN7C;LIN7B;CLASP2
glucose 6-phosphate metabolic process (GO:0051156),3/16,0.028925511,0.243174433,4.38e+9,1.55e+9,TALDO1;PGLS;PGD
G-protein coupled acetylcholine receptor signaling pathway (GO:0007213),3/16,0.028925511,0.242774475,4.38e+9,1.55e+9,GNB1;PLCB1;AGRN
protein localization to chromatin (GO:0071168),3/16,0.028925511,0.24237583,4.38e+9,1.55e+9,H2AFY;H2AFY2;RUVBL2
regulation of histone H3-K4 methylation (GO:0051569),3/16,0.028925511,0.241978493,4.38e+9,1.55e+9,SNW1;H2AFY;CTNNB1
regulation of cholesterol metabolic process (GO:0090181),5/41,0.029884665,0.249593199,2.85e+9,9.99e+9,EPHX2;FASN;APOE;KPNB1;RAN
negative regulation of cell projection organization (GO:0031345),5/41,0.029884665,0.249185367,2.85e+9,9.99e+9,PRNP;PTPRS;CRMP1;APOE;GRIN2B
regulation of substrate adhesion-dependent cell spreading (GO:1900024),5/41,0.029884665,0.248778865,2.85e+9,9.99e+9,CDC42;NRP1;DMTN;RAC1;CORO1C
positive regulation of cell division (GO:0051781),5/41,0.029884665,0.248373688,2.85e+9,9.99e+9,CDC42;PRKCE;PKP4;FGF1;RHOA
positive regulation of endothelial cell migration (GO:0010595),7/70,0.029968539,0.248665781,2.33e+9,8.19e+9,NRP1;ATP5B;ATP5A1;PTK2B;HMGB1;FGF1;RHOB
calcium-mediated signaling (GO:0019722),7/70,0.029968539,0.248262103,2.33e+9,8.19e+9,PRNP;DMTN;ATP2A2;PPP1R9A;ATP1B1;PPP1R9B;SLC9A1
organelle fission (GO:0048285),4/28,0.030241824,0.250119978,3.33e+9,1.17e+9,OPA1;MTFR1L;MFF;GDAP1
positive regulation of cell communication (GO:0010647),4/28,0.030241824,0.249715253,3.33e+9,1.17e+9,RIMS2;RIMS1;SYT1;CLSTN1
positive regulation of phosphate metabolic process (GO:0045937),4/28,0.030241824,0.249311836,3.33e+9,1.17e+9,NRP1;AKR1B1;MIF;SNCA
Ras protein signal transduction (GO:0007265),16/223,0.030980312,0.254987953,1.67e+9,5.82e+9,NCKAP1;RAB5B;GDI1;RAB1B;RHOG;RHOA;RHOB;RAP1B;CDC42;RAB10;RAB35;GNB1;RAB18;CDH13;RAC1;KPNB1
ribosome assembly (GO:0042255),6/56,0.03205041,0.263370757,2.50e+9,8.60e+9,RPL5;RPS14;RPL3;RPS19;RPS5;RPSA
protein modification by small protein removal (GO:0070646),18/261,0.032560559,0.26713269,1.61e+9,5.51e+9,USP14;VCP;PSMD12;USP9X;USP10;AKR1B1;RHOA;PSMB7;UCHL1;PSMD7;PSMC6;APC;PSMD5;HGS;DMWD;PSMB1;COPS8;OTUB1
positive regulation of protein localization to nucleus (GO:1900182),5/42,0.032768739,0.268409112,2.78e+9,9.50e+9,CCT3;TCP1;CCT8;CCT7;CCT5
regulation of striated muscle contraction (GO:0006942),4/29,0.033928303,0.263124819,3.22e+9,1.09e+9,HCN4;ATP1A2;DMD;CALM1
vacuolar transport (GO:0007034),4/29,0.033928303,0.262725541,3.22e+9,1.09e+9,VPS53;AP3D1;ATP6V0D1;VTI1B
regulation of embryonic development (GO:0045995),4/29,0.033928303,0.262327472,3.22e+9,1.09e+9,PHLDB1;TRIP12;PLCB1;CLASP2
regulation of chromosome segregation (GO:0051983),4/29,0.033928303,0.261930607,3.22e+9,1.09e+9,CDC42;DYNC1H1;NUMA1;APC
regulation of keratinocyte differentiation (GO:0045616),4/29,0.033928303,0.261534941,3.22e+9,1.09e+9,NUMA1;H2AFY;H2AFY2;SRSF6
semaphorin-plexin signaling pathway (GO:0071526),4/29,0.033928303,0.261140469,3.22e+9,1.09e+9,NRP1;PLXNB1;RAC1;PLXNA4
positive regulation of epidermal cell differentiation (GO:0045606),3/17,0.03403196,0.261543816,4.12e+9,1.39e+9,H2AFY;NUMA1;H2AFY2
RNA stabilization (GO:0043489),3/17,0.03403196,0.261150517,4.12e+9,1.39e+9,LARP1;CIRBP;ELAVL1
regulation of protein localization to membrane (GO:1905475),3/17,0.03403196,0.260758399,4.12e+9,1.39e+9,STX8;AKR1B1;VTI1B
positive regulation of calcium ion transmembrane transporter activity (GO:1901021),3/17,0.03403196,0.260367457,4.12e+9,1.39e+9,ATP1B1;CALM1;SLC9A1
long-term memory (GO:0007616),3/17,0.03403196,0.259977685,4.12e+9,1.39e+9,PRNP;APOE;SHANK1
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO:0010881),3/17,0.03403196,0.259589079,4.12e+9,1.39e+9,ATP1A2;DMD;CALM1
serine family amino acid metabolic process (GO:0009069),3/17,0.03403196,0.259201633,4.12e+9,1.39e+9,MTHFD1;SARS;SEPHS2
positive chemotaxis (GO:0050918),3/17,0.03403196,0.258815341,4.12e+9,1.39e+9,NRP1;SCRIB;CORO1A
regulation of early endosome to late endosome transport (GO:2000641),3/17,0.03403196,0.258430199,4.12e+9,1.39e+9,MAP2K1;EZR;MAPK3
positive regulation of focal adhesion assembly (GO:0051894),3/17,0.03403196,0.258046202,4.12e+9,1.39e+9,NRP1;THY1;RAC1
regulation of neuron death (GO:1901214),7/72,0.034258402,0.259377779,2.27e+9,7.65e+9,CHGA;PRNP;AKT1S1;CHMP4B;APOE;GRIN2B;SNCA
response to metal ion (GO:0010038),7/72,0.034258402,0.258993515,2.27e+9,7.65e+9,PPP5C;AHCYL1;SLC30A3;SNCB;CALM1;SNCA;PPP1CA
regulation of phosphatase activity (GO:0010921),7/72,0.034258402,0.258610389,2.27e+9,7.65e+9,CAMSAP3;PPP1R2;FARP1;PPP1R12A;DLG3;WNK1;HSP90B1
IRE1-mediated unfolded protein response (GO:0036498),6/57,0.034572993,0.260599682,2.46e+9,8.27e+9,GSK3A;HSPA5;HYOU1;HDGF;TLN1;ATP6V0D1
translational elongation (GO:0006414),9/105,0.036311484,0.273300149,2.00e+9,6.63e+9,EEF1A1;EEFSEC;EEF1G;MRPL40;EEF1A2;MRPS2;MRPL15;EEF2;TUFM
regulation of protein complex assembly (GO:0043254),7/73,0.036548585,0.27467957,2.24e+9,7.41e+9,CDC42;NAPB;HSPA8;HSP90AA1;VCP;STXBP1;PTPN11
regulation of neuron apoptotic process (GO:0043523),8/89,0.036912449,0.277006215,2.10e+9,6.92e+9,NTRK2;PRNP;AKT1S1;AGAP2;PTK2B;CTNNB1;APOE;SOD2
peptidyl-threonine modification (GO:0018210),8/89,0.036912449,0.276599451,2.10e+9,6.92e+9,CAMK2B;GSK3A;MAP2K1;WNK1;CSNK2B;CAMK2A;CAMKK1;DCLK1
positive regulation of GTPase activity (GO:0043547),14/192,0.037157826,0.278029893,1.70e+9,5.60e+9,RHOG;SCRIB;THY1;RANGAP1;CORO1C;SIPA1L1;LARS;PKP4;PLXNB1;GNB5;AGRN;RAB3GAP1;TBC1D10B;RGS7
integrin-mediated signaling pathway (GO:0007229),6/58,0.037220141,0.278088402,2.41e+9,7.94e+9,CDC42;NRP1;ZYX;PTK2B;CD47;THY1
negative regulation of cation channel activity (GO:2001258),4/30,0.037864522,0.282489262,3.11e+9,1.02e+9,FMR1;UBQLN1;GNB5;CALM1
aminoglycan metabolic process (GO:0006022),4/30,0.037864522,0.282076869,3.11e+9,1.02e+9,GPC1;CSPG5;AGRN;CLN6
positive regulation of cellular component organization (GO:0051130),9/106,0.03823848,0.284447468,1.98e+9,6.47e+9,CAMK2B;VCP;GPX1;CLSTN1;AKR1B1;APOE;SHANK3;LRRC4B;SNCA
RNA splicing (GO:0008380),9/106,0.03823848,0.284033425,1.98e+9,6.47e+9,SNRPD2;DDX39B;PPP2R1A;SNRPD1;SRSF4;RNPS1;SNRPD3;PRPF8;PPP1R9B
positive regulation of epithelial cell migration (GO:0010634),7/74,0.038937422,0.288804742,2.21e+9,7.17e+9,NRP1;PRKCE;PTK2B;FGF1;MTOR;RHOB;CLASP2
mitotic nuclear division (GO:0140014),7/74,0.038937422,0.288385577,2.21e+9,7.17e+9,KIF3B;CHMP4B;RHOA;KPNB1;MAP9;RAN;CLASP2
positive regulation of macroautophagy (GO:0016239),5/44,0.039041247,0.288735485,2.65e+9,8.60e+9,GPSM1;LARP1;PIP4K2A;RAB3GAP1;PAFAH1B2
positive regulation of transport (GO:0051050),5/44,0.039041247,0.288317633,2.65e+9,8.60e+9,DYNC1H1;NUMA1;FMR1;APOE;SNCA
regulation of amyloid-beta formation (GO:1902003),3/18,0.039571944,0.291814492,3.89e+9,1.26e+9,PRNP;GSK3A;APOE
establishment of epithelial cell polarity (GO:0090162),3/18,0.039571944,0.291393403,3.89e+9,1.26e+9,CDC42;CAMSAP3;RHOA
release of cytochrome c from mitochondria (GO:0001836),3/18,0.039571944,0.290973528,3.89e+9,1.26e+9,MFF;SOD2;TIMM50
regulation of canonical Wnt signaling pathway (GO:0060828),15/213,0.041208215,0.302569092,1.64e+9,5.24e+9,VCP;PSMD12;GSK3A;CTNND2;PPP1CA;RBX1;PSMB7;PSMD7;PSMC6;APC;PSMD5;WNK1;RUVBL2;PSMB1;APOE
anterograde axonal transport (GO:0008089),4/31,0.042051286,0.30831568,3.01e+9,9.54e+9,AP3M2;KIF3B;FMR1;AP3D1
negative regulation of blood vessel endothelial cell migration (GO:0043537),4/31,0.042051286,0.307873333,3.01e+9,9.54e+9,CSNK2B;HMGB1;APOE;RHOA
positive regulation of protein dephosphorylation (GO:0035307),4/31,0.042051286,0.307432254,3.01e+9,9.54e+9,HSP90AB1;SYMPK;CALM1;MTOR
response to reactive oxygen species (GO:0000302),6/60,0.042894131,0.313145566,2.33e+9,7.35e+9,PRDX3;GPX1;TXNRD1;APOE;SOD2;MAPK3
protein targeting to lysosome (GO:0006622),3/19,0.04553806,0.321856953,3.68e+9,1.14e+9,HSPA8;HGS;LARS
acetylcholine receptor signaling pathway (GO:0095500),3/19,0.04553806,0.321411784,3.68e+9,1.14e+9,GNB1;PLCB1;AGRN
vesicle transport along microtubule (GO:0047496),3/19,0.04553806,0.320967845,3.68e+9,1.14e+9,DYNC1H1;KIF3B;DYNC1I1
purine ribonucleoside bisphosphate metabolic process (GO:0034035),3/19,0.04553806,0.320525131,3.68e+9,1.14e+9,PODXL2;BPNT1;SULT4A1
fatty-acyl-CoA metabolic process (GO:0035337),3/19,0.04553806,0.320083636,3.68e+9,1.14e+9,ACLY;FASN;HSD17B4
nucleotide-sugar biosynthetic process (GO:0009226),3/19,0.04553806,0.319643356,3.68e+9,1.14e+9,UGP2;PMM1;UAP1L1
positive regulation of adherens junction organization (GO:1903393),3/19,0.04553806,0.319204286,3.68e+9,1.14e+9,NRP1;THY1;RAC1
protein heterotetramerization (GO:0051290),3/19,0.04553806,0.31876642,3.68e+9,1.14e+9,CPSF7;RCC1;GRIN2B
mitochondrial membrane organization (GO:0007006),3/19,0.04553806,0.318329753,3.68e+9,1.14e+9,OPA1;SLC25A4;TIMM50
negative regulation of cell junction assembly (GO:1901889),3/19,0.04553806,0.317894282,3.68e+9,1.14e+9,DMTN;CORO1C;CLASP2
positive regulation of heart contraction (GO:0045823),3/19,0.04553806,0.31746,3.68e+9,1.14e+9,CHGA;GSK3A;ATP2A2
NADP metabolic process (GO:0006739),3/19,0.04553806,0.317026903,3.68e+9,1.14e+9,TALDO1;PGLS;PGD
regulation of cellular ketone metabolic process (GO:0010565),6/61,0.045923515,0.319274789,2.30e+9,7.07e+9,PSMB7;PSMD12;PSMD7;PSMC6;PSMD5;PSMB1
regulation of transcription from RNA polymerase II promoter in response to stress (GO:0043618),8/93,0.045990553,0.319305837,2.01e+9,6.18e+9,PSMB7;PSMD12;PSMD7;PSMC6;PSMD5;PSMB1;HIGD1A;RBX1
protein complex disassembly (GO:0043241),5/46,0.045996716,0.318914729,2.54e+8,7.81e+9,VCP;APC;UBQLN1;CTNNB1;PPP1CA
vesicle organization (GO:0016050),10/127,0.046418433,0.321401988,1.84e+9,5.64e+9,SNAP47;SYT1;EXOC8;STX16;STX8;CORO1A;AP2M1;SNX5;VAMP2;VAMP3
mitochondrial transmembrane transport (GO:1990542),4/32,0.046488629,0.321451859,2.92e+9,8.95e+9,AFG3L2;NDUFA13;TIMM29;TIMM9
macroautophagy (GO:0016236),9/110,0.04663936,0.322057721,1.91e+9,5.85e+9,ATG3;VCP;HGS;VTA1;CSNK2B;UBQLN1;CHMP4B;VDAC1;WIPI2
water-soluble vitamin metabolic process (GO:0006767),7/77,0.046707635,0.322093327,2.12e+9,6.50e+9,THTPA;MCCC2;ALDH1L1;MTHFD1;RFK;FASN;PCCB
negative regulation of ubiquitin protein ligase activity (GO:1904667),7/77,0.046707635,0.321658653,2.12e+9,6.50e+9,RPL5;PSMB7;PSMD12;PSMD7;PSMC6;PSMD5;PSMB1
regulation of cytokinesis (GO:0032465),7/77,0.046707635,0.321225151,2.12e+9,6.50e+9,CDC42;PRKCE;PDXP;PKP4;CALM1;RHOA;MAP9
negative regulation of intrinsic apoptotic signaling pathway (GO:2001243),6/62,0.049082541,0.337103909,2.26e+9,6.81e+9,NDUFA13;OPA1;NDUFS3;HYOU1;ENO1;SOD2
cellular amide metabolic process (GO:0043603),6/62,0.049082541,0.336650812,2.26e+9,6.81e+9,MCCC2;SGPL1;PPP2R1A;FASN;PCCB;CPE
cellular protein catabolic process (GO:0044257),6/62,0.049082541,0.336198932,2.26e+9,6.81e+9,CLTC;LONP1;AP2S1;AP2A1;AP2B1;AP2M1
tRNA processing (GO:0008033),6/62,0.049082541,0.335748263,2.26e+9,6.81e+9,CPSF1;CSTF2;SARS;THUMPD1;HSD17B10;AARS