# Supplementary Table S1 - Significant differentially abundant OTUs in the ileum OTU baseMean log2FoldChange lfcSE stat pvalue padj mean_control mean_disease Kingdom Phylum Class Order Family Genus Species TCGGGAATATTGCGCAATGGAGGAAACTCTGACGCAGTGACGCCGCGTGCAGGAAGAAGGTTTTCGGATTGTAAACTGCTTTAGACAGGGAAGAAAAAAGACAGTACCTGTAGAATAAGCTCCGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGGAGCAAGCGTTATCCGGATTTATTGGGTGTAAAGGGTGCGTAGACGGAGAGGCAAGTTAG 5.508822012 28.66456115 1.389341745 20.63175691 1.42E-94 7.94E-92 0.209469349 0 Bacteria Firmicutes Clostridia Clostridiales NA NA NA TGGGGAATATTGCACAATGGGCGAAAGCCTGATGCAGCAACGCCGCGTGAAGGAAGAAGGTCTTCGGATCGTAAACTTCTGTCCTTAGGGAAGATAATGACGGTACCTTTGGAGGAAGCCCCGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGGGGCAAGCGTTATCCGGAATTATTGGGCGTAAAGAGTGCGTAGGTGGTTACCTAAGCAGGG 2.218920752 19.41263645 1.145162586 16.95186053 1.86E-64 5.20E-62 0.034188878 0 Bacteria Firmicutes Clostridia Clostridiales Clostridiaceae NA NA TGAGGAATATTGGTCAATGGCCGAGAGGCTGAACCAGCCAAGTCGCGTGAGGGATGACGGCCCTACGGGTTGTAAACCTCTTTTGCCGGGGAGCAAGAACCGCCTCGCGCAGGCGGACTGAGAGTACCCGGAGAAAAAGCATCGGCTAACTCCGTGCCAGCAGCCGCGGTAATACGGAGGATGCGAGCGTTATCCGGATTCATTGGGTTTAAAGGGTGCG 2.392475282 27.25301811 1.676552515 16.25539186 2.05E-59 3.80E-57 0.192108057 0 Bacteria Bacteroidetes Bacteroidia Bacteroidales S24-7 NA NA TGGGGAATATTGCACAATGGGGGAAACCCTGATGCAGCGACGCCGCGTGAGTGAAGAAGTATTTCGGTATGTAAAGCTCTATCAGCAGGGAAGAAAACAATGACGGTACCTGACTAAGAAGCCCCGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGGGGCAAGCGTTATCCGGATTTACTGGGTGTAAAGGGAGCGTAGACGGCATGGCAAGTC 2.644881904 -22.5008621 1.41793949 -15.86870403 1.04E-56 1.46E-54 0 0.05638548 Bacteria Firmicutes Clostridia Clostridiales NA NA NA TGGGGAATATTGGGCAATGGGGGAAACCCTGACCCAGCAACGCCGCGTGAAGGAAGAAGGCCCTCGGGTTGTAAACTTCTTTTACCAGGGACGAAGGACGTGACGGTACCTGGAGAAAAAGCAACGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGTTGCAAGCGTTGTCCGGATTTACTGGGTGTAAAGGGCGTGTAGGCGGAGATGCAAGTT 6.352874406 -24.92884389 1.676389957 -14.87055192 5.12E-50 5.71E-48 0 0.201834994 Bacteria Firmicutes Clostridia Clostridiales Ruminococcaceae NA NA TGGGGAATATTGCACAATGGGGGAAACCCTGATGCAGCGACGCCGCGTGAGTGAAGAAGTATTTCGGTATGTAAAGCTCTATCAGCAGGGAAGAAAATGACGGTACCTGACTAAGAAGCCCCGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGGGGCAAGCGTTATCCGGATTTACTGGGTGTAAAGGGAGCGTAGACGGCAGGGCAAGTCTGA 8.525785898 27.67062163 2.063626349 13.40873635 5.37E-41 5.00E-39 0.214548847 0 Bacteria Firmicutes Clostridia Clostridiales NA NA NA TGGGGAATATTGCACAATGGAGGAAACTCTGATGCAGCGACGCCGCGTGAGCGAAGAAGTATCTCGGTATGTAAAGCTCTATCAGCAGGGAAGAAAAAAATGACGGTACCTGACTAAGAAGCCCCGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGGGGCAAGCGTTATCCGGATTTACTGGGTGTAAAGGGAGCGCAGGCGGAAGGCTAAGTC 3.084533918 25.6404636 1.941902294 13.20378666 8.34E-40 6.65E-38 0.017425078 0 Bacteria Firmicutes Clostridia Clostridiales Lachnospiraceae NA NA TCGGGAATATTGCGCAATGGAGGAAACTCTGACGCAGTGACGCCGCGTGCAGGAAGAAGGTTTTCGGATTGTAAACTGCTTTAGACAGGGAAGAAAAAGGACAGTACCTGTAGAATAAGCTCCGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGGAGCAAGCGTTATCCGGATTTATTGGGTGTAAAGGGTGCGTAGACGGAGTAGCAAGTTAG 2.047710888 -19.44119712 1.637371668 -11.87341732 1.63E-32 1.13E-30 0 0.005067563 Bacteria Firmicutes Clostridia Clostridiales NA NA NA TGGGGGATATTGCGCAATGGGGGAAACCCTGACGCAGCAATGCCGCGTGAAGGAAGAAGGTTTTCGGATTGTAAACTTCTTTTGTTAAGGACGAAAAAAAGACGGTACTTAACGAATAAGCTCCGGCTAACTATGTGCCAGCAGCCGCGGTAATACATAGGGAGCAAGCGTTATCCGGATTTACTGGGTGTAAAGGGTGCGTAGGCGGCCAATCAAGTCA 0.81709001 30.77404696 2.60252853 11.82467228 2.91E-32 1.80E-30 0.037629671 0 Bacteria Firmicutes Clostridia Clostridiales Ruminococcaceae Ruminococcus NA TAGGGAATATTGGGCAATGGGCGCAAGCCTGACCCAGCAACGCCGCGTGAGGGAAGAAGGTTTTCGGATTGTAAACCTCTGTCCTATGTGACGAAGGAAGTGACGGTAGCATAGGAGGAAGCCCCGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGGGGCGAGCGTTGTCCGGAATTACTGGGCGTAAAGGGTGCGTAGGCGGTTTGGTAAGTT 2.322595998 18.88307335 1.712566172 11.02618612 2.86E-28 1.59E-26 0.055294821 0 Bacteria Firmicutes Clostridia Clostridiales NA NA NA TCGGGAATATTGCGCAATGGAGGAAACTCTGACGCAGTGACGCCGCGTGCAGGAAGAAGGTTTTCGGATTGTAAACTGCTTTAGACAGGGAAGAAACAAGACAGTACCTGTAGAATAAGCTCCGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGGAGCAAGCGTTATCCGGATTTATTGGGTGTAAAGGGTGCGTAGACGGGAAAACAAGTTAG 3.659206689 25.23321269 2.337162613 10.79651563 3.58E-27 1.81E-25 0.086186235 0 Bacteria Firmicutes Clostridia Clostridiales NA NA NA TGGGGGATATTGCGCAATGGGGGAAACCCTGACGCAGCAATGCCGCGTGAAGGAAGAAGGTTTTCGGATTGTAAACTTCTTTTGTTAAGGACGAAAGAATGACGGTACTTAACGAATAAGCTCCGGCTAACTATGTGCCAGCAGCCGCGGTAATACATAGGGAGCAAGCGTTATCCGGATTTACTGGGTGTAAAGGGTGCGTAGGCGGCCAATCAAGTCA 0.810378424 30.81021311 2.863190712 10.76079668 5.27E-27 2.45E-25 0.043192277 0 Bacteria Firmicutes Clostridia Clostridiales Ruminococcaceae Ruminococcus NA TGGGGAATATTGCACAATGGGGGAAACCCTGATGCAGCAACGCCGCGTGAGTGATGACGGCCTTCGGGTTGTAAAGCTCTGTCTTTGGGGACGATAATGACGGTACCCAAGGAGGAAGCCACGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGTGGCAAGCGTTGTCCGGATTTACTGGGCGTAAAGGGAGCGTAGGCGGATTTTTAAGTGGGA 3.371125288 -18.71045232 1.90211774 -9.83664256 7.83E-23 3.36E-21 0.09393539 14.51168624 Bacteria Firmicutes Clostridia Clostridiales Clostridiaceae NA NA TGGGGAATATTGCACAATGGGGGAAACCCTGATGCAGCAACGCCGCGTGAGTGATGACGGTCTTCGGATTGTAAAGCTCTGTCTTTAGGGACGATAATGACGGTACCTAAGGAGGAAGCCACGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGTGGCAAGCGTTGTCCGGATTTACTGGGCGTAAAGGGAGCGTAGGTGGATATTTAAGTGGGA 80.55505941 -9.977655819 1.075842412 -9.274272615 1.79E-20 7.13E-19 2.619354704 439.6080356 Bacteria Firmicutes Clostridia Clostridiales Clostridiaceae Clostridium NA TGAGGAATATTGGTCAATGGGCGTAAGCCTGAACCAGCCAAGTAGCGTGAAGGATGAAGGCTCTCTGGGTCGTAAACTTCTTTTATAAAGGAATAAAGTGGTCTACGTGTAGACTTTTGTATGTACTTTATGAATAAGCATCGGCTAACTCCGTGCCAGCAGCCGCGGTAATACGGAGGATGCGAGCGTTATCCGGATTTATTGGGTTTAAAGGGAGCGT 21.05324947 -10.34557006 1.188231538 -8.706695394 3.13E-18 1.16E-16 0.487990407 2.432759172 Bacteria Bacteroidetes Bacteroidia Bacteroidales Bacteroidaceae Bacteroides NA TCGGGAATATTGCGCAATGGAGGAAACTCTGACGCAGTGACGCCGCGTGCAGGAAGAAGGTTTTCGGATTGTAAACTGCTTTAGACAGGGAAGAAACAAGACAGTACCTGTAGAATAAGCTCCGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGGAGCAAGCGTTATCCGGATTTATTGGGTGTAAAGGGTGCGTAGACGGGAAAGCAAGTTAG 0.523258731 52.48947982 6.18256779 8.489915776 2.07E-17 7.21E-16 0.003306807 0 Bacteria Firmicutes Clostridia Clostridiales NA NA NA TGGGGAATATTGCACAATGGGCGCAAGCCTGATGCAGCCATGCCGCGTGTATGAAGAAGGCCTTCGGGTTGTAAAGTACTTTCAGCGGGGAGGAAGGGAGTAAAGTTAATACCTTTGCTCATTGACGTTACCCGCAGAAGAAGCACCGGCTAACTCCGTGCCAGCAGCCGCGGTAATACGGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCG 402.4581366 -6.458186852 0.810312551 -7.969994847 1.59E-15 5.21E-14 44.46510071 1772.318697 Bacteria Proteobacteria Gammaproteobacteria Enterobacteriales Enterobacteriaceae NA NA TGGGGAATATTGCACAATGGGGGAAACCCTGATGCAGCAACGCCGCGTGAGTGATGACGGCCTTCGGGTTGTAAAGCTCTGTCTTCAGGGACGATAATGACGGTACCTGAGGAGGAAGCCACGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGTGGCGAGCGTTATCCGGATTTACTGGGCGTAAAGGATGCGTAGGTGGAATTTTAAGTGGGA 4.773164343 -16.2166312 2.060814662 -7.869039124 3.57E-15 1.11E-13 0.044791513 4.47776682 Bacteria Firmicutes Clostridia Clostridiales Clostridiaceae Clostridium NA TCGGGAATATTGCGCAATGGAGGAAACTCTGACGCAGTGACGCCGCGTATAGGAAGAAGGTTTTCGGATTGTAAACTATTGTCGTTAGGGAAGATAAAAGACTGTACCTAAGGAGGAAGCCCCGGCTAACTATGTGCCAGCAGCCGCGGTAATACATAGGGGGCAAGCGTTATCCGGAATTATTGGGTGTAAAGGGTGCGTAGACGGGAGAACAAGTTAG 2.738095428 14.70935518 2.056202599 7.153650708 8.45E-13 2.48E-11 0.025641658 0 Bacteria Firmicutes Clostridia Clostridiales NA NA NA TGGGGAATATTGCACAATGGGCGAAAGCCTGATGCAGCGACGCCGCGTGAGTGAAGAAGTATTTCGGTATGTAAAGCTCTATCAGCAGGGAAGAAAATGACGGTACCTGACTAAGAAGCCCCGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGGGGCAAGCGTTATCCGGATTTACTGGGTGTAAAGGGAGCGTAGACGGCGAAGCAAGTCTGA 3.094712981 -16.21810126 2.271228725 -7.140672836 9.29E-13 2.59E-11 0.031378254 0.654442197 Bacteria Firmicutes Clostridia Clostridiales Lachnospiraceae NA NA TGGGGAATATTGCACAATGGGGGAAACCCTGATGCAGCAACGCCGCGTGAGTGATGACGGTCTTCGGATTGTAAAGCTCTGTCTTTAGGGACGATAATGACGGTACCTAAGGAGGAAGCCACGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGTGGCAAGCGTTGTCCGGATTTACTGGGCGTAAAGGGAGCGTAGGCGGATTTTTAAGTGGGA 10.70703472 5.89067854 0.920554331 6.39905581 1.56E-10 4.15E-09 36.11851083 0.083308447 Bacteria Firmicutes Clostridia Clostridiales Clostridiaceae Clostridium NA TGGGGAATATTGCACAATGGGGGAAACCCTGATGCAGCAACGCCGCGTGAGTGATGACGGCCTTCGGGTTGTAAAACTCTGTCTTTGGGGACGATAATGACGGTACCCAAGGAGGAAGCCACGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGTGGCAAGCGTTGTCCGGATTTACTGGGCGTAAAGGGAGCGTAGGTGGATATTTAAGTGGGA 37.84375989 -8.38505028 1.327261729 -6.317555984 2.66E-10 6.74E-09 10.26316115 195.3046024 Bacteria Firmicutes Clostridia Clostridiales Clostridiaceae Clostridium NA TGGGGAATATTGGGCAATGGGCGAAAGCCTGACCCAGCAACGCCGCGTGAAGGAAGAAGGTCTTCGGATTGTAAACTTCTTTTATGAGGGACGAAAACAATGACGGTACCTCATGAATAAGCCACGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGTGGCAAGCGTTATCCGGATTTACTGGGTGTAAAGGGCGCGTAGGCGGGGATGCAAGTC 2.729768791 9.956006505 1.615314594 6.163509287 7.12E-10 1.73E-08 0.224844786 0.013380866 Bacteria Firmicutes Clostridia Clostridiales Ruminococcaceae NA NA TGGGGAATATTGCACAATGGGGGAAACCCTGATGCAGCAACGCCGCGTGAGTGATGAAGGTTTTCGGATCGTAAAGCTCTGTCTTTGGGGAAGATAATGACGGTACCCAAGGAGGAAGCCACGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGTGGCGAGCGTTATCCGGATTTACTGGGCGTAAAGGGAGCGTAGGCGGATGATTAAGTGGGA 89.44389022 -6.995838474 1.188481144 -5.886368926 3.95E-09 9.18E-08 48.82318718 398.6867453 Bacteria Firmicutes Clostridia Clostridiales Clostridiaceae NA NA TGGGGAATATTGCACAATGGGCGCAAGCCTGATGCAGCAACGCCGCGTGAGCGATGAAGGCCTTCGGGTCGTAAAGCTCTGTCCTCAAGGAAGATAATGACGGTACTTGAGGAGGAAGCCCCGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGGGGCTAGCGTTATCCGGATTTACTGGGCGTAAAGGGTGCGTAGGCGGTTTTTTAAGTCAGA 3.496838523 4.020999621 0.79861412 5.034971862 4.78E-07 1.07E-05 4.519199723 0.189100063 Bacteria Firmicutes Clostridia Clostridiales Clostridiaceae NA NA TGGGGAATATTGCACAATGGGCGAAAGCCTGATGCAGCAACGCCGCGTGAGCGATGAAGGCCTTCGGGTCGTAAAGCTCTGTCCTCAAGGAAGATAATGACGGTACTTGAGGAGGAAGCCCCGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGGGGCTAGCGTTATCCGGAATTACTGGGCGTAAAGGGTGCGTAGGCGGTCTTTCAAGCCAGA 215.6072725 -5.131366097 1.107596704 -4.632883141 3.61E-06 7.74E-05 34.984906 1183.903354 Bacteria Firmicutes Clostridia Clostridiales Peptostreptococcaceae NA NA TGGGGAATATTGCACAATGGGCGCAAGCCTGATGCAGCGACGCCGCGTGAAGGATGAAGGTCTTCGGATCGTAAACTTCTATCAGCAGGGAAGAATACCATGACGGTACCTGACTAAGAAGCCCCGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGGGGCAAGCGTTATCCGGAATTACTGGGTGTAAAGGGTGCGTAGGTGGCGATTTAAGTC 15.84743528 -5.231063177 1.137768999 -4.597649594 4.27E-06 8.83E-05 0.662573322 76.33722606 Bacteria Firmicutes Clostridia Clostridiales Lachnospiraceae Epulopiscium NA TGGGGAATATTGCACAATGGGCGAAAGCCTGATGCAGCGACGCCGCGTGAGCGAAGAAGTATTTCGGTATGTAAAGCTCTATCAGCAGGGAAGATAATGACGGTACCTGACTAAGAAGCACCGGCTAAATACGTGCCAGCAGCCGCGGTAATACGTATGGTGCAAGCGTTATCCGGATTTACTGGGTGTAAAGGGAGCGCAGGCGGTACGGCAAGTCTGA 12.19582874 5.266058568 1.167078076 4.51217333 6.42E-06 0.000127875 1.332688943 0.012853963 Bacteria Firmicutes Clostridia Clostridiales Lachnospiraceae NA NA TGAGGAATATTGGTCAATGGACGAGAGTCTGAACCAGCCAAGTAGCGTGAAGGATGACTGCCCTATGGGTTGTAAACTTCTTTTATATGGGAATAAAGTATTCCACGTGTGGGATTTTGTATGTACCATATGAATAAGGATCGGCTAACTCCGTGCCAGCAGCCGCGGTAATACGGAGGATCCGAGCGTTATCCGGATTTATTGGGTTTAAAGGGAGCGT 2.181960099 -5.179243705 1.181868307 -4.382251115 1.17E-05 0.000226008 0 1.228787273 Bacteria Bacteroidetes Bacteroidia Bacteroidales Bacteroidaceae Bacteroides NA TCGAGAATCATTCACAATGGGGGAAACCCTGATGGTGCGACGCCGCGTGGGGGAAGAAGGTCTTCGGATTGTAAACCCCTGTCATGCAGGAGCAAGACGCAAGTTTGATAGTACTGCAAGAGGAAGAGACGGCTAACTCTGTGCCAGCAGCCGCGGTAATACAGAGGTCTCAAGCGTTGTTCGGAATCACTGGGCGTAAAGGGTACGTAGGCTGCAGCAT 4.009210203 -15.91861966 3.643815671 -4.368667653 1.25E-05 0.000232513 0.063562555 0.064250339 Bacteria Verrucomicrobia Verrucomicrobiae Verrucomicrobiales Verrucomicrobiaceae Akkermansia NA TAGGGAATCTTCGGCAATGGGCGAAAGCCTGACCGAGCAACGCCGCGTGAATGATGAAGGCCTTCGGGTTGTAAAATTCTGTTATAAGGGAAGAACGACTTTAGTAGGAAATGGCTAGAGTGTGACGGTACCTTATGAGAAAGCCACGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGTGGCGAGCGTTATCCGGAATTATTGGGCGTAAAGAG 19.13550329 3.051352384 0.719001734 4.243873469 2.20E-05 0.00039545 31.18232853 6.621890416 Bacteria Firmicutes Bacilli Turicibacterales Turicibacteraceae Turicibacter NA TGGGGAATATTGCACAATGGGGGAAACCCTGATGCAGCAACGCCGCGTGAGTGATGAAGGTTTTCGGATCGTAAAGCTCTGTCTTCAGGGACGATAATGACGGTACCTGAGGAGGAAGCCACGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGTGGCGAGCGTTGTCCGGATTTACTGGGCGTAAAGGGAGCGTAGGCGGATTTTTAAGTGAGA 22.26796249 -5.856872578 1.38969505 -4.214502008 2.50E-05 0.000436513 1.285850992 50.29584489 Bacteria Firmicutes Clostridia Clostridiales Clostridiaceae NA NA GCGCGAAACCTCCGCAATGTGAGAAATCGCGACGGGGGGATCCCAAGTGCCATTCTTAACGGGATGGCTTTTCATTAGTGTAAAGAGCTTTTGGAATAAGAGCTGGGCAAGACCGGTGCCAGCCGCCGCGGTAACACCGGCAGCTCTAGTGGTAGCAGTTTTTATTGGGCCTAAAGCGTCCGTAGCCGGTTTAATAAGTCTCTGGTGAAATCTTGCAGCT 2.084201093 4.412499571 1.077101381 4.096642758 4.19E-05 0.000708804 0.69912447 0.016610233 Archaea Euryarchaeota Methanobacteria Methanobacteriales Methanobacteriaceae Methanobrevibacter NA TGGGGAATATTGCACAATGGGGGAAACCCTGATGCAGCGACGCCGCGTGAGCGAAGAAGTATTTCGGTATGTAAAGCTCTATCAGCAGGGAAGAAAATGACGGTACCTGACTAAGAAGCACCGGCTAAATACGTGCCAGCAGCCGCGGTAATACGTATGGTGCAAGCGTTATCCGGATTTACTGGGTGTAAAGGGAGCGTAGACGGTTGTGCAAGTCTGA 4.86721201 -4.31513699 1.057900452 -4.07896318 4.52E-05 0.000742419 0.140491817 0.1751672 Bacteria Firmicutes Clostridia Clostridiales Lachnospiraceae NA NA TCGAGAATCATTCACAATGGGGGCAACCCTGATGGTGCGACGCCGCGTGGGGGAAGAAGGTCTTCGGATTGTAAACCCCTGTCATGTGGGAGCAAGCAGCAATGTTGATAGTACCACAAGAGGAAGAGACGGCTAACTCTGTGCCAGCAGCCGCGGTAATACAGAGGTCTCAAGCGTTGTTCGGAATCACTGGGCGTAAAGAGTACGTAGGCTGTTTTCT 14.176602 -4.752184759 1.173573203 -4.049329645 5.14E-05 0.000818898 0.064104146 0.584415199 Bacteria Verrucomicrobia Verrucomicrobiae Verrucomicrobiales Verrucomicrobiaceae Akkermansia NA TGAGGAATATTGGTCAATGGACGAGAGTCTGAACCAGCCAAGTAGCGTGAAGGATGACTGCCCTATGGGTTGTAAACTTCTTTTATATGGGAATAAAGTGCAGTATGTATACTGTTTTGTATGTACCATACGAATAAGGATCGGCTAACTCCGTGCCAGCAGCCGCGGTAATACGGAGGATCCGAGCGTTATCCGGATTTATTGGGTTTAAAGGGAGCGT 5.103722668 -4.040908351 1.018021436 -3.969374523 7.21E-05 0.001116954 0 0.120062256 Bacteria Bacteroidetes Bacteroidia Bacteroidales Bacteroidaceae Bacteroides NA TGAGGAATATTGGTCAATGGGCGAGAGCCTGAACCAGCCAAGTCGCGTGAGGGAAGACGGTCCTATGGATTGTAAACCTCTTTTGTCGGGGAGCAAGAAGCGGTACGCGTACCGCAGCGAGAGTACCCGAAGAAAAAGCATCGGCTAACTCCGTGCCAGCAGCCGCGGTAATACGGAGGATGCGAGCGTTATCCGGATTTATTGGGTTTAAAGGGTGCGC 13.20807912 -3.893398105 0.985491887 -3.950715532 7.79E-05 0.001175086 0.07164066 0.050818717 Bacteria Bacteroidetes Bacteroidia Bacteroidales S24-7 NA NA TCGAGAATCATTCACAATGGGGGAAACCCTGATGGTGCGACGCCGCGTGGGGGAATGAAGGTCTTCGGATTGTAAACCCCTGTCATGTGGGAGCAAATTAAAAAGATAGTACCACAAGAGGAAGAGACGGCTAACTCTGTGCCAGCAGCCGCGGTAATACAGAGGTCTCAAGCGTTGTTCGGAATCACTGGGCGTAAAGCGTGCGTAGGCTGTTTCGTAA 23.46995383 -3.717758376 0.983002951 -3.782041929 0.000155547 0.002284087 2.966982055 1.870357779 Bacteria Verrucomicrobia Verrucomicrobiae Verrucomicrobiales Verrucomicrobiaceae Akkermansia muciniphila TGGGGAATATTGGGCAATGGGCGCAAGCCTGACCCAGCAACGCCGCGTGAAGGAAGAAGGCTTTCGGGTTGTAAACTTCTTTTGTCAGGGACGAGTAGAAGACGGTACCTGACGAATAAGCCACGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGTGGCAAGCGTTGTCCGGATTTACTGGGTGTAAAGGGCGTGTAGCCGGGAGGGCAAGTCA 6.033161914 -3.670905286 0.972946124 -3.77297899 0.00016131 0.002307972 0.08897713 0.231532585 Bacteria Firmicutes Clostridia Clostridiales Ruminococcaceae NA NA TGGGGAATATTGGGCAATGGGCGCAAGCCTGACCCAGCAACGCCGCGTGAAGGATGAAGGTTTTCGGATTGTAAACTTCTTTTGTCAGGGACGATAATGACGGTACCTGACGAATAAGCCCCGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGGGGCAAGCGTTATCCGGATTTACTGGGTGTAAAGGGCGTGTAGGCGGGATTGCAAGTCAGA 4.100810473 -4.847552485 1.303158523 -3.719848659 0.000199342 0.002754602 0.147219614 0.544771206 Bacteria Firmicutes Clostridia Clostridiales Ruminococcaceae NA NA TGGGGAATATTGCACAATGGGGGGAACCCTGATGCAGCAACGCCGCGTGAAGGAAGAAGTATTTCGGTATGTAAACTTCTATCGACAGGGAAGAAAGAAATGACGGTACCTGAATAAGAAGCACCGGCTAAATACGTGCCAGCAGCCGCGGTAATACGTATGGTGCAAGCGTTATCCGGATTTACTGGGTGTAAAGGGTGAGTAGGCGGTTATGCAAGTC 3.544157043 -7.295486446 1.963261673 -3.716003091 0.000202399 0.002754602 2.009896559 17.59398102 Bacteria Firmicutes Clostridia Clostridiales Lachnospiraceae NA NA TGAGGAATATTGGTCAATGGGCGAGAGCCTGAACCAGCCAAGTCGCGTGAGGGAAGACGGTCCTATGGATTGTAAACCTCTTTTGTCGGGGAGCAAGAAGCGGTACGTGTACCGCAGCGAGAGTACCCGAAGAAAAAGCATCGGCTAACTCCGTGCCAGCAGCCGCGGTAATACGGAGGATGCGAGCGTTATCCGGATTTATTGGGTTTAAAGGGTGCGC 1.861873305 -3.718485653 1.011701347 -3.675477613 0.000237405 0.00312276 0 0.023017706 Bacteria Bacteroidetes Bacteroidia Bacteroidales S24-7 NA NA TGAGGAATATTGGTCAATGGGCGCGAGCCTGAACCAGCCAAGTAGCGTGAAGGATGACGGCCCTATGGGTTGTAAACTTCTTTTATATGGGAATAAAGTTTGGTATGCATACCATTTTGTATGTACCATATGAATAAGGATCGGCTAACTCCGTGCCAGCAGCCGCGGTAATACGGAGGATCCGAGCGTTATCCGGATTTATTGGGTTTAAAGGGAGCGT 28.45710191 -2.650888627 0.721916042 -3.672017899 0.000240643 0.00312276 0.478878921 1.669138061 Bacteria Bacteroidetes Bacteroidia Bacteroidales Bacteroidaceae Bacteroides NA TGAGGAATATTGGTCAATGGGCGCGAGCCTGAACCAGCCAAGTAGCGTGAAGGATGACTGCCCTACGGGTTGTAAACTTCTTTTATAAAGGAATAAAGTGAGGCACGTGTGCCTTTTTGTATGTACTTTATGAATAAGGATCGGCTAACTCCGTGCCAGCAGCCGCGGTAATACGGAGGATCCGAGCGTTATCCGGATTTATTGGGTTTAAAGGGAGCGT 5.744001661 -5.906043652 1.617047192 -3.652363198 0.000259838 0.003295219 0.535330372 0.386543498 Bacteria Bacteroidetes Bacteroidia Bacteroidales Bacteroidaceae Bacteroides NA TGGGGAATATTGCACAATGGGGGGAACCCTGATGCAGCGACGCCGCGTGGAGGAAGAAGGTCTTCGGATTGTAAACTCCTGTTGTTAGGGACGATAATGACGGTACCTAACAAGGAAGCACCGGCTAACTACGTGCCAGCAGCCGCGGTAAAACGTAGGGTGCAAGCGTTGTCCGGAATTACTGGGTGTAAAGGGAGCGCAGGCGGGACTGCAAGTTGGA 1.781766783 -4.249487152 1.174602241 -3.617809506 0.000297107 0.003684126 0 0.102286469 Bacteria Firmicutes Clostridia Clostridiales Ruminococcaceae NA NA TGGGGGATATTGCACAATGGGGGAAACCCTGATGCAGCGACGCCGCGTGTAGGAAGACGGTCCTCTGGATTGTAAACTACTGTCTTCAGGGACGATAATGACGGTACCTGAGGAGGAAGCTCCGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGGAGCGAGCGTTGTCCGGAATTACTGGGTGTAAAGGGAGCGTAGGTGGGAGACTAAGTCCG 0.823528967 -4.132240162 1.144385001 -3.610882838 0.000305156 0.003701681 0 0.185995756 Bacteria Firmicutes Clostridia Clostridiales Ruminococcaceae NA NA TGGGGGATATTGCACAATGGGGGAAACCCTGATGCAGCAACGCCGCGTGTGGGAAGAAGGTTTTCGGATTGTAAACCACTGTTCTTGGTGAAGATAATGACGGTAACCAAGGAGAAAGCTCCGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGGAGCAAGCGTTGTCCGGATTTACTGGGTGTAAAGGGTGCGTAGGCGGCTAGGCAAGTCAGA 1.873899105 -3.571587158 1.012101987 -3.528880691 0.000417321 0.004877623 0.013155372 0.107817626 Bacteria Firmicutes Clostridia Clostridiales Ruminococcaceae Ruminococcus NA TTGGGAATATTGGACAATGGAGGAAACTCTGATCCAGTGACGCCGCGTGAAGGAAGAAGGTCTTCGGATTGTAAACTTATTTTGTCAGGGAAGAAAAAAATGACTGTACCTGAAGAAAAAGCACCGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGGTGCAAGCGTTATCCGGATTTACTGGGTGTAAAGGGCGAGTAGACGGCGTTGCAAGTC 4.944901214 -6.927066847 1.963759581 -3.527451585 0.00041958 0.004877623 0.038639141 0.08601193 Bacteria Firmicutes Clostridia Clostridiales NA NA NA TGGGGAATATTGGGCAATGGGCGCAAGCCTGACCCAGCAACGCCGCGTGAAGGAAGAAGGCTTTCGGGTTGTAAACTTCTTTTGTCAGGGACGAGAAGAAGACGGTACCTGACGAATAAGCCACGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGTGGCAAGCGTTGTCCGGATTTACTGGGTGTAAAGGGCGTGTAGCCGGGTCGGCAAGTCA 2.031640723 -3.599490831 1.022482601 -3.520344336 0.000430987 0.004907973 0.009405417 0.221569682 Bacteria Firmicutes Clostridia Clostridiales Ruminococcaceae NA NA TGGGGAATATTGCACAATGGGGGAAACCCTGATGCAGCAACGCCGCGTGAGTGAAGAAGTATTTCGGTATGTAAAGCTCTATCAGCAGGGAAGAAAATGACGGTACCTGACTAAGAAGCCCCGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGGGGCAAGCGTTATCCGGATTTACTGGGTGTAAAGGGAGCGTAGACGGTTTGGCAAGTCTGA 4.368470306 -4.973950339 1.420296853 -3.502049821 0.000461693 0.005152497 0.006410415 0.067353665 Bacteria Firmicutes Clostridia Clostridiales Lachnospiraceae NA NA TAGGGAATCTTCGGCAATGGGCGAAAGCCTGACCGAGCAACGCCGCGTGAATGAAGAAGGCCTTCGGGTTGTAAAATTCTGTTATAAGGGAAGAAAGGTGATAGGAGGAAATGACTATCAATTGACGGTACCTTATGAGAAAGCCACGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGTGGCAAGCGTTATCCGGAATTATTGGGCGTAAAGAG 7.061692655 2.941225378 0.851775384 3.453052803 0.00055428 0.006064481 17.56299142 1.903709232 Bacteria Firmicutes Bacilli Turicibacterales Turicibacteraceae Turicibacter NA TAGGGAATTTTCGGCAATGGGGGAAACCCTGACCGAGCAACGCCGCGTGAAGGAAGAAGGTTTTCGGATTGTAAACTTCTGTTATAAAGGAAGAACGGCGGCTACAGGAAATGGTAGCCGAGTGACGGTACTTTATTAGAAAGCCACGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGTGGCAAGCGTTATCCGGAATTATTGGGCGTAAAGAG 7.582013657 -3.925981901 1.155230016 -3.398441737 0.000677709 0.007272338 0.342417369 4.499069187 Bacteria Firmicutes Erysipelotrichi Erysipelotrichales Erysipelotrichaceae NA NA TGAGGAATATTGGTCAATGGGCGCAGGCCTGAACCAGCCAAGTAGCGTGAAGGATGACTGCCCTATGGGTTGTAAACTTCTTTTATATGGGAATAAAGTTTTCCACGTGTGGAATTTTGTATGTACCATATGAATAAGGATCGGCTAACTCCGTGCCAGCAGCCGCGGTAATACGGAGGATCCGAGCGTTATCCGGATTTATTGGGTTTAAAGGGAGCGT 37.06629315 -2.850745751 0.843144784 -3.381086861 0.000721997 0.007601404 0.404947398 3.541118954 Bacteria Bacteroidetes Bacteroidia Bacteroidales Bacteroidaceae Bacteroides ovatus TGGGGAATATTGCGCAATGGGCGAAAGCCTGACGCAGCGACGCCGCGTGAGGGATGAAGGTTCTCGGATCGTAAACCTCTGTCAGGGGGGAAGAAACCCCCTCGTGTGAATAATGCGAGGGCTTGACGGTACCCCCAAAGGAAGCACCGGCTAACTCCGTGCCAGCAGCCGCGGTAATACGGAGGGTGCAAGCGTTAATCGGAATCACTGGGCGTAAAGC 3.20991933 -2.875498899 0.854249693 -3.366110543 0.000762362 0.007877736 0.166325853 0.340049144 Bacteria Proteobacteria Deltaproteobacteria Desulfovibrionales Desulfovibrionaceae Bilophila NA TGGGGAATATTGCACAATGGGGGAAACCCTGATGCAGCGACGCCGCGTGGAGGAAGAAGGTCTTCGGATTGTAAACTCCTGTCGTGTAGGACGATAGTGACGGTACTACACAAGAAAGCCACGGCTAACTACGTGCCAGCAGCCGCGGTAAAACGTAGGTGGCAAGCGTTGTCCGGAATTACTGGGTGTAAAGGGAGCGCAGGCGGGCTTGCAAGTTGGA 5.856294997 -4.387065623 1.315943649 -3.333779243 0.000856746 0.00869208 0.128970894 0.157451185 Bacteria Firmicutes Clostridia Clostridiales Ruminococcaceae NA NA TGGGGAATATTGGGCAATGGGCGCAAGCCTGACCCAGCAACGCCGCGTGAAGGAAGAAGGCTTTCGGGTTGTAAACTTCTTTTGACAGGGACGAAACAAATGACGGTACCTGTAGAATAAGCTCCGGCTAAATACGTGCCAGCAGCCGCGGTAATACGTATGGAGCAAGCGTTATCCGGATTTACTGGGTGTAAAGGGCGCGTAGGCGGGACTTCAAGTC 2.213324714 -3.298181348 0.998688609 -3.302512233 0.000958229 0.009548068 0.008547219 0.10083614 Bacteria Firmicutes Clostridia Clostridiales Ruminococcaceae NA NA